# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Retrotran_gag_2 PF14223.6 OAJ08057.1 - 5.9e-10 38.9 0.0 7.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ08061.1 - 2e-18 66.7 0.0 3.2e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08061.1 - 9.1e-10 38.3 0.1 1.5e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ08061.1 - 7.7e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.6 OAJ08061.1 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 OAJ08061.1 - 0.024 15.0 0.0 0.066 13.6 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain Prp19 PF08606.11 OAJ08076.1 - 7.2e-29 99.6 1.8 1.3e-28 98.7 1.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like TMF_TATA_bd PF12325.8 OAJ08076.1 - 0.011 15.9 1.2 0.066 13.4 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pex19 PF04614.12 OAJ08076.1 - 0.08 12.7 2.1 0.11 12.3 2.1 1.2 1 0 0 1 1 1 0 Pex19 protein family MukF_M PF17192.4 OAJ08076.1 - 0.08 12.7 1.0 0.17 11.6 0.5 1.6 1 1 0 2 2 2 0 MukF middle domain Cep57_CLD_2 PF14197.6 OAJ08076.1 - 0.56 10.3 5.6 0.2 11.7 1.9 2.1 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 OAJ08076.1 - 2.2 8.8 5.5 1.1 9.7 0.7 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Chromo PF00385.24 OAJ08082.1 - 2.7e-16 59.2 0.2 4.6e-16 58.5 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 OAJ08082.1 - 6e-08 32.9 0.0 1.6e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Drf_FH1 PF06346.12 OAJ08095.1 - 2.4e-06 27.4 56.9 0.0034 17.1 22.0 3.9 1 1 2 3 3 3 2 Formin Homology Region 1 Sugar_tr PF00083.24 OAJ08120.1 - 5.8e-18 65.0 0.3 6.8e-18 64.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Condensation PF00668.20 OAJ08127.1 - 1.2e-19 70.3 0.0 1.3e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 Condensation domain Retrotran_gag_2 PF14223.6 OAJ08133.1 - 1.3e-06 28.2 0.5 1.6e-06 27.9 0.5 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Zip PF02535.22 OAJ08138.1 - 4.2e-11 42.7 3.9 4.2e-11 42.7 3.9 2.6 2 1 0 2 2 2 1 ZIP Zinc transporter Helicase_C PF00271.31 OAJ08147.1 - 6.6e-10 39.3 0.0 3e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3877 PF12993.7 OAJ08147.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DEAD PF00270.29 OAJ08147.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Het-C PF07217.11 OAJ08153.1 - 3.3e-57 194.3 0.0 4.4e-57 193.9 0.0 1.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1572 PF07609.11 OAJ08153.1 - 0.074 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) GTA_TIM PF13547.6 OAJ08153.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 GTA TIM-barrel-like domain Phage_integrase PF00589.22 OAJ08164.1 - 0.0037 17.1 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MLVIN_C PF18697.1 OAJ08167.1 - 0.00039 20.4 0.0 0.00078 19.5 0.0 1.6 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain MCM_bind PF09739.9 OAJ08172.1 - 5.1e-48 163.9 0.0 5.5e-47 160.5 0.0 1.9 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor RT_RNaseH PF17917.1 OAJ08194.1 - 5.7e-13 49.1 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08194.1 - 2e-06 27.7 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PDZ_5 PF17817.1 OAJ08194.1 - 0.047 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF5497 PF17601.2 OAJ08198.1 - 5.7e-05 23.4 0.7 2.2 8.6 0.0 4.0 5 0 0 5 5 5 1 Family of unknown function (DUF5497) TPR_12 PF13424.6 OAJ08198.1 - 0.0017 18.6 13.5 1.8 8.9 0.4 5.1 2 2 2 4 4 4 4 Tetratricopeptide repeat MIT PF04212.18 OAJ08198.1 - 0.094 12.8 2.0 0.73 9.9 0.1 3.1 1 1 3 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OAJ08198.1 - 0.78 9.7 13.2 6.1 6.9 0.0 5.7 4 3 3 7 7 7 0 Tetratricopeptide repeat UPF0262 PF06793.12 OAJ08198.1 - 0.79 9.8 4.0 8.5 6.5 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0262) DUF4439 PF14530.6 OAJ08198.1 - 3.1 8.5 20.4 2.8 8.7 0.2 4.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4439) Neuraminidase PF18413.1 OAJ08202.1 - 0.036 13.7 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain Dicer_dimer PF03368.14 OAJ08227.1 - 0.00082 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain rve PF00665.26 OAJ08236.1 - 5e-18 65.4 0.0 8.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08236.1 - 4.7e-09 36.0 0.0 9.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ08236.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_1_2 PF13586.6 OAJ08236.1 - 0.003 17.9 0.0 0.013 15.9 0.0 2.0 2 0 0 2 2 2 1 Transposase DDE domain DDE_3 PF13358.6 OAJ08236.1 - 0.049 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Methyltransf_24 PF13578.6 OAJ08241.1 - 0.071 14.1 0.0 0.11 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RVT_2 PF07727.14 OAJ08242.1 - 2e-24 86.6 0.0 2.2e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ08263.1 - 0.00019 21.3 5.2 0.025 14.6 1.1 2.6 2 0 0 2 2 2 2 Zinc knuckle Anti-TRAP PF15777.5 OAJ08263.1 - 0.04 13.9 0.4 0.04 13.9 0.4 2.4 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Retrotran_gag_2 PF14223.6 OAJ08284.1 - 6.6e-18 64.7 0.2 9.6e-18 64.2 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ08284.1 - 2.2e-05 24.3 8.9 0.0042 17.1 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ08284.1 - 0.005 16.8 8.0 0.096 12.7 1.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ08284.1 - 0.044 13.6 2.0 0.044 13.6 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAJ08284.1 - 1.1 9.0 10.4 0.72 9.6 1.8 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 OAJ08284.1 - 3 7.6 10.7 5 6.9 1.9 2.5 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 OAJ08287.1 - 9.3e-15 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 OAJ08293.1 - 1e-07 32.1 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein Luciferase_N PF05295.11 OAJ08293.1 - 0.011 15.7 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain RVP_2 PF08284.11 OAJ08294.1 - 1.9e-11 43.9 0.1 3.1e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ08294.1 - 8.2e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ08294.1 - 1.1e-05 25.9 0.0 2.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OAJ08294.1 - 0.0011 19.3 0.0 0.006 16.9 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease PF09668.10 OAJ08294.1 - 0.005 16.6 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Rif1_N PF12231.8 OAJ08301.1 - 0.02 13.9 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Peptidase_S8 PF00082.22 OAJ08309.1 - 3.3e-14 52.9 2.1 5e-14 52.3 2.1 1.3 1 0 0 1 1 1 1 Subtilase family ocr PF08684.10 OAJ08309.1 - 0.065 13.7 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA mimic ocr RVT_2 PF07727.14 OAJ08313.1 - 3.5e-24 85.8 0.1 5e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08313.1 - 9.3e-18 64.5 0.0 2.4e-17 63.2 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 OAJ08313.1 - 9.9e-05 22.1 0.0 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.6 OAJ08313.1 - 0.043 13.6 0.1 0.094 12.5 0.0 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 OAJ08313.1 - 0.044 14.1 0.0 0.14 12.6 0.0 1.9 1 1 0 1 1 1 0 Transposase DDE domain Dam PF05869.11 OAJ08313.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) SIR2 PF02146.17 OAJ08325.1 - 5.2e-08 33.0 0.1 9e-08 32.2 0.1 1.4 2 0 0 2 2 2 1 Sir2 family Viral_helicase1 PF01443.18 OAJ08327.1 - 2.7e-07 30.6 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAJ08327.1 - 0.059 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAJ08327.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ08327.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ETX_MTX2 PF03318.13 OAJ08327.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 AAA_30 PF13604.6 OAJ08336.1 - 1.4e-08 34.7 0.4 1.5e-08 34.6 0.4 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 OAJ08336.1 - 3.2e-07 29.8 0.1 3.7e-07 29.6 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 OAJ08336.1 - 6.4e-06 26.6 0.3 7.3e-06 26.4 0.3 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ08336.1 - 0.00017 21.5 0.0 0.00022 21.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAJ08336.1 - 0.00091 18.4 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 OAJ08336.1 - 0.0012 18.4 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 OAJ08336.1 - 0.0017 18.6 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 OAJ08336.1 - 0.0035 16.8 0.1 0.0042 16.6 0.1 1.1 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.26 OAJ08336.1 - 0.0045 16.7 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.12 OAJ08336.1 - 0.0066 16.4 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 OAJ08336.1 - 0.0085 15.4 0.2 0.01 15.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ08336.1 - 0.0095 16.0 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 OAJ08336.1 - 0.016 14.9 0.5 0.38 10.5 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ08336.1 - 0.026 14.9 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAJ08336.1 - 0.03 13.9 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 OAJ08336.1 - 0.04 14.3 0.3 0.049 14.1 0.3 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAJ08336.1 - 0.049 13.5 0.1 0.069 13.1 0.1 1.2 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 OAJ08336.1 - 0.073 13.6 0.1 0.077 13.5 0.1 1.2 1 0 0 1 1 1 0 ABC transporter Phage_Capsid_P3 PF09018.11 OAJ08336.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 P3 major capsid protein cobW PF02492.19 OAJ08336.1 - 0.22 11.1 0.1 0.28 10.8 0.1 1.1 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 OAJ08336.1 - 0.3 11.0 0.0 0.38 10.6 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 OAJ08336.1 - 0.32 10.5 0.3 0.36 10.3 0.3 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RmuC PF02646.16 OAJ08357.1 - 0.0019 17.4 0.4 0.002 17.3 0.4 1.0 1 0 0 1 1 1 1 RmuC family BLOC1_2 PF10046.9 OAJ08357.1 - 0.0099 16.2 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2388 PF09498.10 OAJ08357.1 - 0.023 14.7 2.7 0.037 14.0 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2388) Wtap PF17098.5 OAJ08357.1 - 0.029 14.3 0.8 0.032 14.2 0.8 1.0 1 0 0 1 1 1 0 WTAP/Mum2p family DUF2514 PF10721.9 OAJ08357.1 - 0.041 13.9 6.2 0.042 13.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DivIC PF04977.15 OAJ08357.1 - 0.069 12.9 1.8 0.093 12.5 1.8 1.3 1 0 0 1 1 1 0 Septum formation initiator PNP_phzG_C PF10590.9 OAJ08372.1 - 0.054 13.6 0.4 0.09 12.9 0.4 1.3 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region zf-CCHC PF00098.23 OAJ08401.1 - 0.00061 19.7 1.5 0.001 19.0 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ08401.1 - 0.084 13.2 0.1 0.26 11.6 0.1 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein ubiquitin PF00240.23 OAJ08414.1 - 0.00023 20.8 0.0 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Lambda_tail_I PF06805.12 OAJ08418.1 - 0.03 14.7 0.2 0.068 13.5 0.0 1.6 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I Sugar_tr PF00083.24 OAJ08424.1 - 7.7e-90 301.9 11.2 2.4e-88 297.0 11.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ08424.1 - 1.2e-18 67.1 25.5 5.1e-18 65.1 24.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF441 PF04284.13 OAJ08424.1 - 0.0065 16.5 2.2 0.0065 16.5 2.2 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF441) MFS_5 PF05631.14 OAJ08424.1 - 0.0085 15.1 0.1 0.0085 15.1 0.1 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM PagL PF09411.10 OAJ08424.1 - 0.0086 16.2 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Lipid A 3-O-deacylase (PagL) DUF2530 PF10745.9 OAJ08424.1 - 0.86 9.9 9.5 0.22 11.8 3.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) Condensation PF00668.20 OAJ08427.1 - 1.5e-06 27.2 0.0 2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 OAJ08427.1 - 4.1e-05 23.8 0.0 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site PAP2_3 PF14378.6 OAJ08427.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily RVT_1 PF00078.27 OAJ08436.1 - 1.9e-05 24.3 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5349 PF17298.2 OAJ08436.1 - 1.4 8.6 6.5 1.7 8.4 6.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) RT_RNaseH_2 PF17919.1 OAJ08437.1 - 1.6e-17 63.3 0.1 2.5e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08437.1 - 0.00023 21.4 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Flavin_Reduct PF01613.18 OAJ08448.1 - 0.009 16.1 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain TMP_2 PF06791.13 OAJ08448.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein RNA_pol_Rpb2_6 PF00562.28 OAJ08456.1 - 1.1e-79 268.3 0.2 1.3e-79 268.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 OAJ08456.1 - 1e-29 102.8 0.1 2e-29 101.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 TLP1_add_C PF18313.1 OAJ08460.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Septin PF00735.18 OAJ08476.1 - 1.9e-65 221.0 0.0 2.2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ08476.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ08476.1 - 1.6e-05 24.9 0.1 2.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAJ08476.1 - 6.8e-05 23.0 0.2 0.14 12.3 0.1 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 OAJ08476.1 - 0.00029 20.2 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 OAJ08476.1 - 0.0008 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 OAJ08476.1 - 0.0015 18.1 0.1 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 OAJ08476.1 - 0.0017 17.9 0.7 0.0091 15.5 0.1 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAJ08476.1 - 0.0046 17.2 0.1 0.006 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAJ08476.1 - 0.006 17.1 0.1 0.0074 16.8 0.1 1.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 OAJ08476.1 - 0.0066 16.8 0.0 0.0091 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 OAJ08476.1 - 0.0076 16.0 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.22 OAJ08476.1 - 0.052 12.7 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 OAJ08476.1 - 0.063 12.3 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 OAJ08476.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PPV_E1_C PF00519.17 OAJ08476.1 - 0.079 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase IIGP PF05049.13 OAJ08476.1 - 0.086 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 OAJ08476.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 OAJ08476.1 - 0.12 11.2 0.1 0.23 10.2 0.0 1.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF815 PF05673.13 OAJ08476.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.7 OAJ08476.1 - 0.16 10.8 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AMP-binding PF00501.28 OAJ08485.1 - 1.1e-71 241.6 0.1 1.4e-71 241.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sporozoite_P67 PF05642.11 OAJ08490.1 - 0.043 11.9 0.2 0.035 12.2 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2310 PF10071.9 OAJ08505.1 - 0.037 13.3 0.7 0.079 12.2 0.1 1.7 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) SlyX PF04102.12 OAJ08521.1 - 0.0093 16.6 0.7 0.013 16.1 0.7 1.2 1 0 0 1 1 1 1 SlyX DUF3138 PF11336.8 OAJ08521.1 - 1.5 7.3 5.9 1.8 7.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Flg_bb_rod PF00460.20 OAJ08521.1 - 2.3 8.2 4.9 16 5.5 2.0 2.4 2 0 0 2 2 2 0 Flagella basal body rod protein Integrase_H2C2 PF17921.1 OAJ08522.1 - 5.3e-22 77.7 0.0 1.3e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ08522.1 - 7.8e-15 54.5 0.2 1.4e-14 53.7 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 OAJ08522.1 - 3.4e-13 49.8 0.0 6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08522.1 - 2.7e-07 30.7 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ08522.1 - 3.1e-05 24.2 0.6 6.2e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_Tyr PF07714.17 OAJ08526.1 - 1.3e-05 24.7 0.0 1.5e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAJ08526.1 - 0.00085 18.8 0.0 0.0011 18.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain SDA1 PF05285.12 OAJ08526.1 - 0.076 12.4 0.3 0.092 12.2 0.3 1.0 1 0 0 1 1 1 0 SDA1 AMP-binding PF00501.28 OAJ08531.1 - 3.3e-79 266.5 0.0 4.4e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme SIR2 PF02146.17 OAJ08536.1 - 3.4e-26 92.3 0.0 4.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family DUF4141 PF13605.6 OAJ08542.1 - 0.091 12.0 1.5 0.14 11.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Pkinase PF00069.25 OAJ08568.1 - 1.3e-30 106.6 0.0 4.4e-30 104.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08568.1 - 1.3e-17 63.9 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ08568.1 - 3.8e-05 23.7 6.8 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family TFIIA PF03153.13 OAJ08568.1 - 0.031 14.3 24.0 0.049 13.6 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 OAJ08568.1 - 0.11 11.1 18.9 0.16 10.6 18.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase_fungal PF17667.1 OAJ08568.1 - 0.15 10.8 3.3 0.58 8.9 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase DUF2927 PF11150.8 OAJ08568.1 - 0.18 11.9 8.0 0.31 11.1 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) DUF1682 PF07946.14 OAJ08568.1 - 0.58 9.3 10.3 0.76 8.9 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5427 PF10310.9 OAJ08577.1 - 0.61 9.0 3.6 0.71 8.8 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TIP49 PF06068.13 OAJ08580.1 - 4.5e-49 167.5 0.0 6.9e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ08580.1 - 3.1e-24 84.9 1.9 5.7e-24 84.0 1.9 1.5 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 OAJ08580.1 - 0.1 12.3 0.5 0.51 10.1 0.0 2.1 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ08580.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain FERM_f0 PF16511.5 OAJ08588.1 - 0.025 14.9 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM HTH_Tnp_Tc5 PF03221.16 OAJ08598.1 - 3.4e-07 30.2 0.0 5.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2545 PF10810.8 OAJ08602.1 - 0.007 16.5 0.5 0.022 14.9 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2545) RTC4 PF14474.6 OAJ08629.1 - 0.15 12.2 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 RTC4-like domain TPR_10 PF13374.6 OAJ08638.1 - 1e-28 98.3 32.8 2.7e-06 27.0 0.8 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08638.1 - 2.4e-21 75.8 33.7 1.5e-07 31.6 5.5 5.8 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08638.1 - 2e-14 52.5 13.7 0.054 13.6 0.2 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ08638.1 - 2.4e-14 52.2 10.7 0.14 12.5 0.1 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08638.1 - 1e-12 47.2 6.3 0.6 10.0 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ08638.1 - 2e-09 36.8 19.2 0.77 9.9 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ08638.1 - 8.5e-06 26.2 27.5 0.9 10.5 0.5 6.9 5 2 2 7 7 6 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ08638.1 - 1.6e-05 24.9 14.4 4.8 7.3 0.0 6.0 3 1 1 6 6 6 1 Anaphase-promoting complex subunit 5 Desmo_N PF06771.11 OAJ08638.1 - 2.9e-05 24.3 0.0 4.3 7.8 0.0 4.6 1 1 5 6 6 6 1 Viral Desmoplakin N-terminus SHNi-TPR PF10516.9 OAJ08638.1 - 0.00011 21.5 2.3 20 4.7 0.0 5.4 5 0 0 5 5 5 0 SHNi-TPR Mad3_BUB1_II PF08171.11 OAJ08638.1 - 0.00014 21.9 7.2 21 5.4 0.1 5.3 5 0 0 5 5 5 0 Mad3/BUB1 homology region 2 Pkinase_fungal PF17667.1 OAJ08638.1 - 0.0014 17.5 2.3 5.1 5.8 0.0 4.6 4 1 0 4 4 4 1 Fungal protein kinase DUF3856 PF12968.7 OAJ08638.1 - 0.0021 18.1 11.9 0.046 13.8 2.5 3.5 1 1 2 3 3 3 3 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 OAJ08638.1 - 0.0058 17.2 15.6 7.4 7.5 0.5 6.5 6 0 0 6 6 5 1 Tetratricopeptide repeat Cytochrom_B562 PF07361.11 OAJ08638.1 - 0.0075 16.9 3.3 69 4.2 0.0 4.9 5 0 0 5 5 5 0 Cytochrome b562 CBP_BcsQ PF06564.12 OAJ08638.1 - 0.019 14.4 13.6 11 5.4 0.2 5.0 3 2 2 5 5 5 0 Cellulose biosynthesis protein BcsQ Sipho_Gp157 PF05565.11 OAJ08638.1 - 0.06 13.4 12.7 0.37 10.8 0.3 4.4 2 1 3 5 5 4 0 Siphovirus Gp157 DUF4810 PF16068.5 OAJ08638.1 - 0.063 13.8 0.1 37 5.0 0.0 3.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4810) PPR PF01535.20 OAJ08638.1 - 0.33 11.3 13.1 40 4.8 0.0 5.7 6 0 0 6 6 5 0 PPR repeat TPR_16 PF13432.6 OAJ08638.1 - 1 10.1 21.7 13 6.6 0.8 5.8 3 1 2 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 OAJ08638.1 - 1.5 8.5 9.6 14 5.4 0.2 4.4 2 2 3 5 5 5 0 26S proteasome subunit RPN7 Nitr_red_bet_C PF14711.6 OAJ08638.1 - 2.7 7.8 6.0 1.1e+02 2.5 0.0 4.4 4 1 1 5 5 5 0 Respiratory nitrate reductase beta C-terminal Bradykinin PF06753.12 OAJ08638.1 - 3.9 7.3 17.5 11 5.8 0.2 5.7 6 0 0 6 6 6 0 Bradykinin DUF4726 PF15855.5 OAJ08638.1 - 6.4 7.1 12.8 93 3.3 0.2 4.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4726) Hydrolase PF00702.26 OAJ08642.1 - 1.3e-14 55.0 0.5 2.7e-14 54.0 0.5 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ08642.1 - 5e-05 23.2 0.3 8.6e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EB PF01683.18 OAJ08655.1 - 8 6.8 141.6 0.029 14.7 10.3 13.3 2 2 8 11 11 11 0 EB module Mating_C PF12737.7 OAJ08661.1 - 0.028 13.7 3.9 0.032 13.5 3.9 1.0 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RhoGEF67_u1 PF16615.5 OAJ08667.1 - 0.018 15.5 0.2 0.018 15.5 0.2 2.2 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 DUF935 PF06074.12 OAJ08667.1 - 0.11 11.2 0.7 0.13 11.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Mso1_C PF14477.6 OAJ08681.1 - 0.1 13.0 0.6 0.1 13.0 0.6 1.8 2 0 0 2 2 2 0 Membrane-polarising domain of Mso1 Retrotran_gag_2 PF14223.6 OAJ08698.1 - 7.8e-16 58.0 0.1 1e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 OAJ08698.1 - 0.061 13.1 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ08699.1 - 6e-05 22.9 9.5 0.013 15.6 1.1 2.5 2 0 0 2 2 2 2 Zinc knuckle gag_pre-integrs PF13976.6 OAJ08699.1 - 0.0056 16.5 0.6 0.026 14.4 0.0 2.4 3 0 0 3 3 3 1 GAG-pre-integrase domain zf-CCHC_3 PF13917.6 OAJ08699.1 - 0.0069 16.3 8.6 0.055 13.4 2.2 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ08699.1 - 0.85 9.5 12.0 0.15 11.9 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ08699.1 - 2.6 7.8 9.8 8.7 6.2 1.3 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAJ08699.1 - 5.8 6.7 10.3 6.5 6.6 1.7 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_6 PF15288.6 OAJ08699.1 - 6.3 6.7 12.1 9.2 6.2 2.0 2.5 2 0 0 2 2 2 0 Zinc knuckle 4HBT_3 PF13622.6 OAJ08705.1 - 6.2e-19 69.2 1.1 1.1e-18 68.5 1.1 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily M64_N PF16217.5 OAJ08705.1 - 0.0005 19.6 0.1 0.0011 18.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase M64 N-terminus SMN PF06003.12 OAJ08711.1 - 0.67 9.2 9.3 0.97 8.6 9.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-CCHC PF00098.23 OAJ08714.1 - 0.001 19.1 1.2 0.0015 18.5 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL1 PF05259.11 OAJ08714.1 - 0.0055 16.7 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Herpesvirus glycoprotein L Retrotrans_gag PF03732.17 OAJ08714.1 - 0.0068 16.7 0.0 0.022 15.0 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1192 PF06698.11 OAJ08714.1 - 0.015 15.3 0.9 0.046 13.8 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-CCHC_2 PF13696.6 OAJ08714.1 - 0.025 14.4 0.9 0.04 13.7 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 OAJ08714.1 - 0.03 14.7 0.7 0.081 13.3 0.7 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Pox_Ag35 PF03286.14 OAJ08714.1 - 2.4 7.9 9.2 0.75 9.6 3.0 2.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DDE_Tnp_4 PF13359.6 OAJ08728.1 - 1e-05 25.3 0.0 0.00073 19.2 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease Peptidase_S8 PF00082.22 OAJ08745.1 - 5.7e-33 114.4 0.0 2.5e-32 112.3 0.0 1.9 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ08745.1 - 1.1e-16 61.6 0.2 2.6e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 Fn3-like domain DUF11 PF01345.18 OAJ08745.1 - 0.00087 19.6 0.2 0.0041 17.4 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF11 fn3_6 PF17766.1 OAJ08745.1 - 0.0021 18.2 0.1 0.0062 16.7 0.1 1.9 1 1 0 1 1 1 1 Fibronectin type-III domain ASH PF15780.5 OAJ08745.1 - 0.0069 16.6 0.1 0.067 13.4 0.1 2.2 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin NPCBM_assoc PF10633.9 OAJ08745.1 - 0.04 14.2 0.9 11 6.4 0.0 3.1 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Motile_Sperm PF00635.26 OAJ08745.1 - 0.052 13.4 0.9 0.08 12.8 0.2 1.6 2 0 0 2 2 2 0 MSP (Major sperm protein) domain N_BRCA1_IG PF16158.5 OAJ08745.1 - 0.13 13.0 0.0 0.37 11.6 0.0 1.7 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene RPT PF13446.6 OAJ08745.1 - 0.19 11.7 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Big_2 PF02368.18 OAJ08745.1 - 0.27 11.2 2.9 0.42 10.5 0.4 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) RVT_2 PF07727.14 OAJ08767.1 - 8.2e-62 209.0 0.0 1.4e-61 208.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ08781.1 - 2.7e-31 107.9 0.0 5.6e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08781.1 - 6.8e-31 107.5 0.0 1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08781.1 - 1.6e-21 76.2 0.0 5.3e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08781.1 - 1.1e-11 44.7 0.0 2.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08781.1 - 2e-05 24.8 0.0 7.6e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08781.1 - 0.071 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger VbhA PF18495.1 OAJ08801.1 - 0.22 11.4 1.3 15 5.5 0.2 2.8 2 0 0 2 2 2 0 Antitoxin VbhA DUF3533 PF12051.8 OAJ08810.1 - 1.2e-72 244.9 22.1 1.5e-72 244.6 22.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) FlaC_arch PF05377.11 OAJ08815.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) HHH_3 PF12836.7 OAJ08815.1 - 0.055 13.7 0.1 0.99 9.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif LOH1CR12 PF10158.9 OAJ08815.1 - 0.066 13.2 0.5 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Tumour suppressor protein KIP1 PF07765.12 OAJ08815.1 - 0.13 12.4 0.9 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 KIP1-like protein DUF1664 PF07889.12 OAJ08815.1 - 0.13 12.3 0.8 0.2 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_60s PF00428.19 OAJ08815.1 - 1.7 9.2 10.2 1.9 9.1 5.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RCC1 PF00415.18 OAJ08826.1 - 7.8e-46 154.5 3.2 1.7e-07 31.8 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ08826.1 - 3e-28 97.0 30.9 5.6e-07 29.2 0.5 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF4767 PF15983.5 OAJ08826.1 - 0.39 11.0 1.4 0.68 10.2 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) FHA PF00498.26 OAJ08832.1 - 0.0051 17.1 0.1 0.0098 16.2 0.1 1.4 1 0 0 1 1 1 1 FHA domain DUF2618 PF10940.8 OAJ08839.1 - 0.031 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) TPR_10 PF13374.6 OAJ08855.1 - 5.6e-15 54.7 11.7 1.5e-06 27.9 0.5 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08855.1 - 9.3e-10 38.7 18.7 0.00042 20.5 4.2 5.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08855.1 - 0.00027 20.8 8.3 0.73 10.1 0.2 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08855.1 - 0.0018 18.0 2.0 3.4 7.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat PTN13_u3 PF16599.5 OAJ08855.1 - 0.017 15.2 5.0 0.036 14.1 5.0 1.4 1 0 0 1 1 1 0 Unstructured linker region on PTN13 protein between PDZ TPR_8 PF13181.6 OAJ08855.1 - 0.22 11.8 5.5 4.1 7.8 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ08855.1 - 2.6 8.8 11.2 1.5 9.5 0.5 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Yae1_N PF09811.9 OAJ08861.1 - 0.0085 15.8 0.8 0.014 15.1 0.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal zf-CCHC PF00098.23 OAJ08861.1 - 0.0091 16.0 2.2 0.02 15.0 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ08861.1 - 0.39 10.5 1.4 0.7 9.7 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle CLIP1_ZNF PF16641.5 OAJ08871.1 - 0.038 13.9 2.8 0.041 13.8 0.6 2.2 3 0 0 3 3 3 0 CLIP1 zinc knuckle XRN1_D1 PF18332.1 OAJ08871.1 - 0.13 12.0 0.3 0.21 11.3 0.3 1.2 1 0 0 1 1 1 0 Exoribonuclease Xrn1 D1 domain DUF5401 PF17380.2 OAJ08871.1 - 0.42 8.6 10.2 0.57 8.2 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4192 PF13830.6 OAJ08871.1 - 0.86 9.6 12.8 1.6 8.7 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) RhlB PF12300.8 OAJ08871.1 - 4.3 7.5 17.5 0.045 13.9 8.5 2.1 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Folliculin PF11704.8 OAJ08871.1 - 6.6 6.6 5.5 12 5.7 5.5 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Integrase_H2C2 PF17921.1 OAJ08879.1 - 4e-22 78.1 0.1 9.4e-22 76.9 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ08879.1 - 8.6e-22 77.4 0.6 1.5e-21 76.7 0.6 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08879.1 - 4.4e-15 55.9 0.0 8.2e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ08879.1 - 9.5e-06 25.6 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ08879.1 - 6.5e-05 23.1 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH_2 PF17919.1 OAJ08880.1 - 1.6e-17 63.3 0.1 2.5e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08880.1 - 0.00022 21.5 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Oxidored-like PF09791.9 OAJ08913.1 - 0.00024 20.7 0.2 0.00052 19.6 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ATPgrasp_N PF18130.1 OAJ08913.1 - 0.0082 16.7 0.1 0.013 16.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp N-terminal domain AHSP PF09236.10 OAJ08913.1 - 0.025 15.0 0.3 0.038 14.4 0.2 1.4 1 1 0 1 1 1 0 Alpha-haemoglobin stabilising protein DDE_Tnp_1_2 PF13586.6 OAJ08913.1 - 0.038 14.4 2.3 0.038 14.4 2.3 1.6 1 1 1 2 2 2 0 Transposase DDE domain TPR_10 PF13374.6 OAJ08920.1 - 9.4e-16 57.1 13.9 5.4e-07 29.3 0.5 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08920.1 - 8.3e-10 38.8 13.2 8.7e-08 32.3 3.7 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08920.1 - 0.0003 20.7 4.4 0.59 10.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ08920.1 - 0.00048 20.1 3.5 0.56 10.6 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ08920.1 - 0.00064 20.1 0.0 1.5 9.7 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat NUC130_3NT PF08158.12 OAJ08920.1 - 0.0017 18.6 0.2 14 6.1 0.0 3.6 3 1 0 3 3 3 1 NUC130/3NT domain TPR_7 PF13176.6 OAJ08920.1 - 0.0038 17.2 2.5 2.8 8.2 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAJ08920.1 - 0.014 14.2 0.0 16 4.1 0.0 3.0 3 0 0 3 3 3 0 Fungal protein kinase DUF3856 PF12968.7 OAJ08920.1 - 0.042 13.9 0.7 0.1 12.7 0.7 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) HI0933_like PF03486.14 OAJ08921.1 - 0.016 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Gly_rich PF12810.7 OAJ08921.1 - 2.7 7.8 23.4 46 3.8 23.4 2.0 1 1 0 1 1 1 0 Glycine rich protein Ribonuclease_3 PF00636.26 OAJ08933.1 - 1e-10 42.1 0.0 2.7e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ08933.1 - 1.7e-05 25.0 0.0 0.00021 21.4 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAJ08934.1 - 1.2e-06 29.0 0.0 2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain DDE_Tnp_4 PF13359.6 OAJ08935.1 - 5.2e-19 68.5 0.0 6.1e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.17 OAJ08941.1 - 0.0074 16.5 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein TPR_2 PF07719.17 OAJ08954.1 - 5.2e-05 23.0 0.0 2 8.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ08954.1 - 0.00036 20.8 1.8 0.91 9.9 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08954.1 - 0.00059 19.5 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ08954.1 - 0.00094 19.0 2.2 0.27 11.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ08954.1 - 0.004 17.8 0.3 11 6.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ08954.1 - 0.0075 17.0 5.9 0.1 13.5 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ08954.1 - 0.086 13.5 6.2 1.3 9.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CODH_A_N PF18537.1 OAJ08954.1 - 0.13 12.3 0.2 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain HTH_23 PF13384.6 OAJ08961.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Homeodomain-like domain CPSase_L_D3 PF02787.19 OAJ08961.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain RT_RNaseH PF17917.1 OAJ08966.1 - 2.7e-23 82.2 0.0 3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08966.1 - 2.3e-20 72.5 0.0 2.5e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08967.1 - 1.9e-13 50.3 0.1 5.2e-13 48.9 0.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08967.1 - 2.4e-13 50.3 0.0 5.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08967.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain BAR_3_WASP_bdg PF10456.9 OAJ08970.1 - 0.045 13.2 0.0 0.046 13.2 0.0 1.0 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Gelsolin PF00626.22 OAJ08984.1 - 1.3e-36 124.3 0.1 5.6e-14 51.8 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat BMP2K_C PF15282.6 OAJ08984.1 - 0.04 13.8 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus 60KD_IMP PF02096.20 OAJ08990.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein COX7B PF05392.11 OAJ08993.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Helitron_like_N PF14214.6 OAJ09002.1 - 1e-18 68.3 0.0 1.9e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AMP-binding PF00501.28 OAJ09013.1 - 6.8e-78 262.1 0.0 1e-77 261.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAJ09013.1 - 2.2e-42 145.3 0.0 3.2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Ribosomal_L28e PF01778.17 OAJ09025.1 - 4.9e-35 120.7 1.6 6.1e-35 120.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OAJ09025.1 - 4.2e-23 81.8 32.2 4.2e-23 81.8 32.2 3.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAJ09025.1 - 1.9e-07 30.8 27.2 2.6e-07 30.4 27.2 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 OAJ09025.1 - 0.0078 16.0 2.0 0.014 15.1 2.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Treacle PF03546.14 OAJ09025.1 - 0.0089 14.9 6.8 0.015 14.1 6.8 1.3 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle TFIIA PF03153.13 OAJ09025.1 - 0.0092 16.0 21.4 0.013 15.5 21.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OAJ09025.1 - 1.9 6.6 43.2 2.7 6.1 43.2 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 OAJ09025.1 - 3.8 6.2 13.5 5.2 5.7 13.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1664 PF07889.12 OAJ09026.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SKA1 PF07160.12 OAJ09026.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FlxA PF14282.6 OAJ09026.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 FlxA-like protein DUF948 PF06103.11 OAJ09026.1 - 0.22 11.8 0.0 0.75 10.1 0.0 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) UDPGT PF00201.18 OAJ09034.1 - 8e-12 44.7 0.1 1.1e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.13 OAJ09034.1 - 0.085 13.2 0.8 3.4 8.1 0.0 2.5 1 1 1 2 2 2 0 GHMP kinases C terminal NOA36 PF06524.12 OAJ09039.1 - 0.4 10.0 4.2 0.62 9.3 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 OAJ09039.1 - 0.75 9.3 4.3 1.1 8.8 4.3 1.2 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.6 OAJ09039.1 - 0.97 9.8 6.3 1.8 9.0 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAJ09039.1 - 5.6 4.9 5.8 7.5 4.5 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_3 PF07859.13 OAJ09043.1 - 9.5e-10 38.7 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pribosyltran_N PF13793.6 OAJ09043.1 - 4.2e-07 29.9 0.1 6.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Abhydrolase_6 PF12697.7 OAJ09043.1 - 0.0029 18.3 0.3 0.0055 17.3 0.2 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAJ09043.1 - 0.027 14.0 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family MapZ_EC1 PF18041.1 OAJ09044.1 - 0.0095 16.2 8.2 0.026 14.8 2.7 2.1 2 0 0 2 2 2 2 MapZ extracellular domain 1 Peroxin-13_N PF04088.13 OAJ09051.1 - 3.4e-42 144.2 0.0 4.6e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 OAJ09051.1 - 1.5e-12 46.9 0.0 3.3e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ09051.1 - 3.1e-12 46.0 0.0 5.3e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ09051.1 - 6.8e-10 38.7 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.22 OAJ09052.1 - 2.6e-16 59.2 0.0 4.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 OAJ09052.1 - 0.052 13.7 10.5 0.091 12.9 10.5 1.4 1 1 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 OAJ09052.1 - 0.33 9.4 3.8 0.43 9.1 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAJ09052.1 - 3 6.0 20.1 0.025 12.8 9.4 1.9 2 0 0 2 2 2 0 Nop14-like family HbrB PF08539.11 OAJ09057.1 - 8.2e-28 97.5 5.6 2.5e-27 96.0 0.0 3.8 2 1 0 2 2 2 1 HbrB-like RT_RNaseH PF17917.1 OAJ09062.1 - 2.7e-35 120.8 0.0 6e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09062.1 - 3.6e-31 107.1 0.0 8.6e-31 105.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09062.1 - 1.2e-29 103.5 0.1 2e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09062.1 - 4.4e-22 77.9 0.0 1.5e-21 76.2 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ09062.1 - 1.5e-13 50.4 0.1 2.9e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 OAJ09062.1 - 2.9e-12 46.8 0.0 6e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09062.1 - 1.2e-06 28.6 0.0 6.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger G-patch PF01585.23 OAJ09079.1 - 1e-06 28.5 0.3 2.7e-06 27.1 0.3 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 OAJ09079.1 - 0.0013 19.0 1.6 0.002 18.4 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ09079.1 - 0.043 14.2 0.4 0.078 13.4 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3449 PF11931.8 OAJ09079.1 - 0.55 10.0 9.4 0.041 13.7 1.9 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) Dor1 PF04124.12 OAJ09080.1 - 0.026 13.2 4.8 0.46 9.1 1.9 2.3 2 0 0 2 2 2 0 Dor1-like family DUF515 PF04415.12 OAJ09080.1 - 0.026 12.9 0.4 0.042 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Myb_DNA-bind_3 PF12776.7 OAJ09088.1 - 2e-14 54.3 0.0 2.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Nucleocap_ssRNA PF11128.8 OAJ09088.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Reprolysin_4 PF13583.6 OAJ09105.1 - 0.043 13.5 0.2 0.09 12.4 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sec3_C PF09763.9 OAJ09105.1 - 0.046 12.1 1.6 0.068 11.5 1.6 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 SesA PF17107.5 OAJ09105.1 - 0.13 12.4 2.4 0.49 10.6 1.0 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Nup54 PF13874.6 OAJ09105.1 - 0.4 10.8 2.5 0.3 11.2 0.8 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Med3 PF11593.8 OAJ09112.1 - 1.9 7.6 8.0 2.3 7.3 8.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GreA_GreB PF01272.19 OAJ09131.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term Robl_LC7 PF03259.17 OAJ09131.1 - 4.1 7.2 5.0 15 5.4 0.0 2.9 2 1 0 2 2 2 0 Roadblock/LC7 domain 2TM PF13239.6 OAJ09132.1 - 0.18 12.1 0.4 17 5.8 0.5 2.3 2 0 0 2 2 2 0 2TM domain RVT_1 PF00078.27 OAJ09140.1 - 7.2e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.14 OAJ09155.1 - 2e-10 40.3 0.0 3.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 PPV_E1_C PF00519.17 OAJ09155.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase CDC45 PF02724.14 OAJ09155.1 - 0.9 7.8 4.6 1.3 7.2 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.20 OAJ09163.1 - 0.00031 19.1 3.0 0.00034 18.9 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Selenoprotein_S PF06936.11 OAJ09163.1 - 0.11 12.3 0.8 0.15 11.9 0.8 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) ATP-synt_B PF00430.18 OAJ09163.1 - 1.1 9.3 7.3 1.4 9.0 7.3 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HSP70 PF00012.20 OAJ09164.1 - 3.1e-253 841.4 6.5 3.5e-253 841.2 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ09164.1 - 4.5e-16 58.6 0.3 1.1e-14 54.0 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAJ09164.1 - 0.004 17.5 1.8 2.1 8.8 0.0 3.3 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OAJ09164.1 - 0.012 14.9 0.2 0.026 13.8 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 OAJ09164.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 OAJ09164.1 - 0.027 14.0 0.1 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MIT PF04212.18 OAJ09167.1 - 1.5e-06 28.2 6.2 6.3 7.0 0.1 7.5 7 1 1 8 8 8 3 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 OAJ09167.1 - 9e-05 22.7 24.9 5.7 7.3 0.1 10.3 9 3 3 12 12 12 3 Tetratricopeptide repeat CheD PF03975.13 OAJ09167.1 - 0.00062 19.8 2.7 15 5.7 0.0 6.6 5 4 3 8 8 8 1 CheD chemotactic sensory transduction DUF4439 PF14530.6 OAJ09167.1 - 0.013 16.2 23.3 5.2 7.8 0.2 7.2 3 1 5 9 9 9 0 Domain of unknown function (DUF4439) DUF4332 PF14229.6 OAJ09167.1 - 0.035 14.3 16.1 0.92 9.8 0.2 7.3 6 2 2 8 8 8 0 Domain of unknown function (DUF4332) HflK_N PF12221.8 OAJ09167.1 - 0.042 13.9 11.2 12 6.0 0.0 6.8 8 0 0 8 8 8 0 Bacterial membrane protein N terminal PDDEXK_1 PF12705.7 OAJ09167.1 - 0.084 12.8 4.5 3.7 7.4 0.1 3.7 3 1 1 4 4 4 0 PD-(D/E)XK nuclease superfamily TPR_10 PF13374.6 OAJ09167.1 - 0.11 12.5 31.0 22 5.1 0.0 11.8 12 2 1 13 13 13 0 Tetratricopeptide repeat KASH_CCD PF14662.6 OAJ09171.1 - 0.0022 17.8 2.4 0.035 13.9 0.3 2.2 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH DUF2353 PF09789.9 OAJ09171.1 - 0.061 12.7 1.2 0.084 12.2 0.9 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 OAJ09171.1 - 0.083 11.8 4.1 1.6 7.6 0.8 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cdh1_DBD_1 PF18196.1 OAJ09171.1 - 0.09 13.1 0.2 0.18 12.1 0.2 1.4 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF641 PF04859.12 OAJ09171.1 - 0.092 13.1 2.3 10 6.4 0.2 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 OAJ09171.1 - 0.1 12.9 1.9 1.2 9.5 0.2 2.5 1 1 0 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 OAJ09171.1 - 0.1 12.7 4.7 2.7 8.0 0.8 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 OAJ09171.1 - 0.13 12.1 2.4 3.1 7.7 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator HrpB7 PF09486.10 OAJ09171.1 - 0.18 12.2 5.7 0.58 10.5 0.5 2.1 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMEM61 PF15105.6 OAJ09171.1 - 0.22 11.3 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 TMEM61 protein family SlyX PF04102.12 OAJ09171.1 - 1.2 9.8 4.1 2.7 8.7 0.7 2.5 1 1 2 3 3 3 0 SlyX WD40 PF00400.32 OAJ09182.1 - 0.023 15.5 0.4 16 6.6 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat HGTP_anticodon PF03129.20 OAJ09183.1 - 2.7e-09 37.1 0.0 3.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 OAJ09183.1 - 2.3e-05 24.0 0.0 2.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs WD40 PF00400.32 OAJ09184.1 - 6.9e-12 45.7 3.7 0.0061 17.4 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 OAJ09184.1 - 0.017 13.8 0.1 0.57 8.7 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PGC7_Stella PF15549.6 OAJ09189.1 - 0.038 14.0 0.4 0.09 12.8 0.4 1.6 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Med3 PF11593.8 OAJ09189.1 - 0.92 8.6 12.3 0.059 12.6 6.7 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RAP1 PF07218.11 OAJ09189.1 - 2.8 6.1 4.2 5.3 5.2 4.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHC PF01529.20 OAJ09193.1 - 2.5 8.2 15.4 5.8 7.0 0.8 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase PIN_12 PF16289.5 OAJ09198.1 - 4.9 7.6 8.9 5.8 7.4 8.9 1.1 1 0 0 1 1 1 0 PIN domain Asp_protease_2 PF13650.6 OAJ09202.1 - 0.011 16.3 0.0 0.027 15.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 OAJ09202.1 - 0.04 14.0 3.5 0.073 13.2 3.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.12 OAJ09202.1 - 0.081 13.0 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CCHC_3 PF13917.6 OAJ09202.1 - 0.63 10.1 5.4 0.063 13.3 0.8 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09202.1 - 0.81 9.6 2.5 1.3 8.9 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle MCR PF18509.1 OAJ09202.1 - 2.3 7.9 4.4 7.9 6.2 0.7 2.4 2 0 0 2 2 2 0 Magnetochrome domain MFS_1_like PF12832.7 OAJ09211.1 - 0.00015 20.7 0.7 0.0002 20.4 0.7 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 OAJ09211.1 - 0.00064 18.8 27.9 0.0012 17.9 28.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily AMP-binding PF00501.28 OAJ09220.1 - 6.6e-73 245.7 0.0 9.3e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAJ09220.1 - 1.5e-35 122.8 0.0 2.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 OAJ09220.1 - 9.8e-12 45.1 0.5 1e-09 38.6 0.0 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ09220.1 - 0.013 16.5 0.0 0.037 15.0 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Het-C PF07217.11 OAJ09224.1 - 1.3e-39 136.2 1.6 1.8e-39 135.7 1.6 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DDE_Tnp_4 PF13359.6 OAJ09234.1 - 6.3e-15 55.2 0.0 8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease F-box PF00646.33 OAJ09237.1 - 0.00095 19.0 0.1 0.0019 18.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain AAA_assoc_2 PF16193.5 OAJ09238.1 - 2.3e-05 24.6 0.0 3.8e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA C-terminal domain Rep_fac_C PF08542.11 OAJ09238.1 - 0.0069 16.8 0.0 0.018 15.5 0.0 1.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 OAJ09238.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Integrase_H2C2 PF17921.1 OAJ09242.1 - 1.8e-21 76.0 0.1 3.9e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09242.1 - 2.3e-14 53.6 0.0 4.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09242.1 - 6.1e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger AdoMet_MTase PF07757.13 OAJ09251.1 - 0.0013 19.1 0.0 0.002 18.4 0.0 1.2 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Asp_protease_2 PF13650.6 OAJ09256.1 - 2.3e-05 24.9 0.1 6.4e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ09256.1 - 0.00056 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 OAJ09256.1 - 0.018 15.6 0.0 0.066 13.8 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ09256.1 - 0.019 15.3 0.0 0.072 13.4 0.0 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ09257.1 - 0.0009 19.2 1.5 0.0009 19.2 1.5 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ09257.1 - 0.026 14.5 0.3 0.047 13.7 0.3 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ09257.1 - 0.028 14.1 1.1 0.057 13.1 1.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zinc_ribbon_2 PF13240.6 OAJ09257.1 - 0.076 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain RdRP_2 PF00978.21 OAJ09263.1 - 4.1e-13 49.0 0.0 5.7e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Viral_helicase1 PF01443.18 OAJ09263.1 - 0.031 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Serpin PF00079.20 OAJ09263.1 - 0.078 12.3 0.1 0.11 11.8 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) CRAL_TRIO PF00650.20 OAJ09283.1 - 3.2e-26 91.9 0.0 5.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ09283.1 - 9.2e-11 41.8 0.6 3.7e-10 39.8 0.4 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ09283.1 - 4.5e-05 23.6 0.0 7.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pkinase PF00069.25 OAJ09292.1 - 1.5e-34 119.6 0.0 1.7e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09292.1 - 2.5e-24 86.0 0.0 2.8e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ09292.1 - 5.6e-05 23.2 0.0 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ09292.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 RIO1 family rve PF00665.26 OAJ09298.1 - 1.4e-05 25.2 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ09298.1 - 1.6e-05 24.6 0.0 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Dam PF05869.11 OAJ09298.1 - 0.044 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) gag_pre-integrs PF13976.6 OAJ09299.1 - 6.2e-09 35.6 0.1 1.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ09299.1 - 0.0001 22.2 9.5 0.015 15.3 1.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ09299.1 - 0.056 13.4 9.2 0.06 13.3 1.7 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09299.1 - 1.2 9.0 12.0 0.19 11.6 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ09299.1 - 6.7 6.5 10.0 15 5.4 1.7 2.6 2 0 0 2 2 2 0 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ09300.1 - 9.1e-17 61.0 0.2 1.1e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-H2C2_2 PF13465.6 OAJ09320.1 - 1.7e-21 75.6 21.6 6.5e-08 32.7 0.1 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 OAJ09320.1 - 6.4e-21 73.6 23.5 3.9e-05 23.9 0.3 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ09320.1 - 3.5e-12 46.0 24.5 0.021 15.6 2.2 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ09320.1 - 0.00011 22.4 3.0 0.2 12.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 OAJ09320.1 - 0.0062 16.8 1.8 0.0062 16.8 1.8 3.0 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 OAJ09320.1 - 0.0077 16.6 11.8 2.3 8.7 0.3 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 OAJ09320.1 - 0.11 12.6 16.3 0.35 10.9 0.2 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger BolA PF01722.18 OAJ09320.1 - 0.2 12.0 3.7 0.68 10.2 0.8 2.6 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_11 PF16622.5 OAJ09320.1 - 0.62 9.9 17.1 0.071 12.9 2.0 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAJ09320.1 - 2.6 8.1 10.4 0.35 10.8 0.5 3.9 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Cortexin PF11057.8 OAJ09331.1 - 0.079 12.8 0.6 0.22 11.4 0.6 1.8 1 1 0 1 1 1 0 Cortexin of kidney p450 PF00067.22 OAJ09332.1 - 8.3e-65 219.3 0.0 1.9e-64 218.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.11 OAJ09351.1 - 4.3e-09 36.5 0.0 4.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 OAJ09351.1 - 0.02 13.7 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.32 OAJ09351.1 - 0.043 14.7 0.1 0.069 14.0 0.1 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat Antifungal_pept PF11410.8 OAJ09356.1 - 0.028 14.3 0.3 0.028 14.3 0.3 2.9 3 0 0 3 3 3 0 Antifungal peptide LEAP-2 PF07359.11 OAJ09356.1 - 0.32 10.9 1.9 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) CHAD PF05235.14 OAJ09360.1 - 1.5e-05 25.1 2.2 1.7e-05 24.9 2.2 1.2 1 0 0 1 1 1 1 CHAD domain PGA2 PF07543.12 OAJ09360.1 - 0.92 9.5 7.5 1.4 8.9 7.5 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2235 PF09994.9 OAJ09361.1 - 1.6e-65 221.3 0.0 2.4e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) adh_short PF00106.25 OAJ09366.1 - 1.8e-27 96.1 0.3 1.4e-25 89.9 0.3 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ09366.1 - 7.4e-18 65.0 0.1 4.5e-16 59.1 0.1 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ09366.1 - 9.5e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ09366.1 - 0.0012 18.8 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ09366.1 - 0.026 13.9 0.1 0.049 13.0 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) MBG PF17883.1 OAJ09366.1 - 0.047 14.3 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 MBG domain GDP_Man_Dehyd PF16363.5 OAJ09366.1 - 0.048 13.1 0.1 0.48 9.8 0.1 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 OAJ09376.1 - 2.1e-15 56.8 1.2 1.5e-10 40.9 0.0 3.0 2 1 1 3 3 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09376.1 - 1.7e-08 34.1 0.1 8.8e-06 25.2 0.0 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase TFIIA PF03153.13 OAJ09376.1 - 0.00076 19.6 37.2 0.00098 19.2 37.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 OAJ09376.1 - 0.12 10.6 35.0 0.14 10.4 35.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 OAJ09376.1 - 0.12 11.1 21.5 0.15 10.8 21.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.6 OAJ09376.1 - 0.13 11.9 25.7 0.21 11.2 25.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 OAJ09376.1 - 0.24 10.4 14.7 0.31 10.0 14.7 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 OAJ09376.1 - 1.8 8.0 25.9 2.5 7.6 25.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 OAJ09376.1 - 2.8 7.1 7.9 3.9 6.6 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 OAJ09376.1 - 3.1 6.4 22.3 4 6.0 22.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endostatin PF06482.11 OAJ09376.1 - 3.8 6.9 17.6 7.1 6.0 17.6 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 OAJ09376.1 - 7.1 5.5 18.9 11 4.8 18.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 OAJ09376.1 - 8.9 6.0 27.0 12 5.7 25.8 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 OAJ09383.1 - 2.1e-06 27.3 0.0 2.6e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09383.1 - 0.00089 18.6 0.0 0.35 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase zf-CCHC PF00098.23 OAJ09388.1 - 0.00037 20.4 9.8 0.11 12.6 1.4 2.3 2 0 0 2 2 2 2 Zinc knuckle Nefa_Nip30_N PF10187.9 OAJ09388.1 - 0.18 12.2 0.3 1.1 9.7 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 RVT_2 PF07727.14 OAJ09389.1 - 6e-61 206.2 0.0 8.5e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09389.1 - 1.1e-16 61.0 0.4 9.9e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09389.1 - 1.2e-08 34.7 1.7 4.2e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09389.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Propeptide_C1 PF08127.13 OAJ09389.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Peptidase family C1 propeptide RRP7 PF12923.7 OAJ09396.1 - 0.02 15.1 1.3 0.035 14.2 1.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TRAM_2 PF18693.1 OAJ09396.1 - 0.19 11.9 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 TRAM domain Pkinase PF00069.25 OAJ09406.1 - 6.8e-26 91.2 0.0 7.8e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09406.1 - 4.2e-14 52.5 0.0 5.1e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ09406.1 - 0.032 13.5 0.0 0.047 13.0 0.0 1.3 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OAJ09406.1 - 0.066 12.8 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family QRPTase_C PF01729.19 OAJ09413.1 - 6e-43 146.5 0.2 7.5e-43 146.2 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain LysR_substrate PF03466.20 OAJ09413.1 - 0.041 13.2 0.3 0.061 12.7 0.3 1.4 1 1 0 1 1 1 0 LysR substrate binding domain SPA PF08616.10 OAJ09414.1 - 0.0092 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis PIF1 PF05970.14 OAJ09422.1 - 4e-26 92.1 0.0 1.1e-24 87.3 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase SelB-wing_3 PF09107.11 OAJ09426.1 - 0.067 12.8 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Elongation factor SelB, winged helix LST1 PF05083.13 OAJ09426.1 - 0.1 12.9 0.5 0.17 12.2 0.5 1.3 1 0 0 1 1 1 0 LST-1 protein KfrA_N PF11740.8 OAJ09426.1 - 0.32 11.7 19.0 0.28 11.9 2.1 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term MULE PF10551.9 OAJ09443.1 - 6.2e-23 81.0 0.0 1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ09443.1 - 5.4e-09 35.4 0.0 8.8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Fis1_TPR_N PF14852.6 OAJ09443.1 - 0.052 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat Pkinase PF00069.25 OAJ09448.1 - 2.3e-26 92.7 0.0 3.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09448.1 - 4.6e-22 78.6 0.0 6.7e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase dsrm PF00035.26 OAJ09448.1 - 0.00022 21.9 0.2 0.00022 21.9 0.2 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif RNA_pol_Rpb2_6 PF00562.28 OAJ09449.1 - 0.029 13.4 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 UreE_C PF05194.12 OAJ09456.1 - 0.053 14.0 0.0 0.078 13.5 0.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Condensation PF00668.20 OAJ09466.1 - 1e-87 294.8 0.0 1.3e-46 159.2 0.0 2.1 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 OAJ09466.1 - 5.7e-73 245.9 0.0 8.3e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ09466.1 - 0.054 14.5 0.4 0.32 12.0 0.1 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain EAL PF00563.20 OAJ09466.1 - 0.097 12.2 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 EAL domain RVT_2 PF07727.14 OAJ09470.1 - 5.2e-61 206.4 0.0 7.2e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09470.1 - 1.3e-18 67.3 0.6 3.6e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ09470.1 - 1.1e-11 44.5 0.0 2.2e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ09470.1 - 1.1e-08 34.7 2.3 1e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ09470.1 - 4.7e-05 23.3 9.1 0.048 13.8 2.2 2.7 2 0 0 2 2 2 2 Zinc knuckle rve_3 PF13683.6 OAJ09470.1 - 0.00029 20.5 0.1 0.006 16.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain zf-C2H2_10 PF16588.5 OAJ09470.1 - 0.41 10.4 1.4 1.2 9.0 1.4 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger MCM_bind PF09739.9 OAJ09477.1 - 2.4e-05 23.0 0.0 2.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor ZapB PF06005.12 OAJ09487.1 - 0.023 15.1 9.0 0.059 13.8 9.0 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Chibby PF14645.6 OAJ09487.1 - 0.13 12.7 4.5 0.36 11.3 4.5 1.7 1 1 0 1 1 1 0 Chibby family bZIP_2 PF07716.15 OAJ09487.1 - 0.78 9.9 15.7 0.96 9.6 10.4 2.5 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 OAJ09487.1 - 0.86 9.4 9.3 2.2 8.1 9.3 1.6 1 0 0 1 1 1 0 Septum formation initiator Rootletin PF15035.6 OAJ09487.1 - 1 9.3 10.5 0.058 13.4 5.0 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion PikAIV_N PF18605.1 OAJ09487.1 - 8.6 6.0 13.1 0.64 9.7 2.6 3.1 1 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NRBF2 PF08961.10 OAJ09487.1 - 9.6 5.8 12.6 0.2 11.2 5.3 1.9 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Aldedh PF00171.22 OAJ09488.1 - 4.5e-29 101.3 0.7 8.9e-14 50.8 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family RVT_1 PF00078.27 OAJ09495.1 - 9.5e-24 84.1 0.0 2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09495.1 - 4.2e-19 68.4 0.0 4.6e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09495.1 - 8.7e-14 51.7 0.0 4.6e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09495.1 - 4.9e-13 49.0 0.0 9.3e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09495.1 - 2.2e-10 40.8 0.0 6.6e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09495.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RVT_2 PF07727.14 OAJ09498.1 - 1.8e-46 158.7 0.1 1.7e-36 126.1 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09498.1 - 1.1e-16 61.1 0.0 2.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ09498.1 - 8.8e-16 57.8 0.1 1.7e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ09498.1 - 1.3e-08 34.6 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09498.1 - 0.00019 21.1 0.0 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 OAJ09498.1 - 0.033 14.3 10.2 0.067 13.3 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF4537 PF15057.6 OAJ09498.1 - 0.1 12.6 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) zf-CCHC_3 PF13917.6 OAJ09498.1 - 8.1 6.5 12.0 0.83 9.7 1.1 2.7 3 0 0 3 3 3 0 Zinc knuckle WD40 PF00400.32 OAJ09503.1 - 7.7e-08 32.9 2.2 0.0011 19.7 0.0 4.4 4 1 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAJ09503.1 - 0.049 12.4 0.0 6 5.5 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like zf-RING_2 PF13639.6 OAJ09510.1 - 1.6e-10 41.2 2.1 2.3e-10 40.6 0.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAJ09510.1 - 3.2e-10 40.1 1.4 5.5e-10 39.4 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 OAJ09510.1 - 8.6e-07 28.7 0.2 8.6e-07 28.7 0.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ09510.1 - 3.2e-06 26.9 2.2 6.9e-06 25.8 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ09510.1 - 1.9e-05 24.5 1.4 4e-05 23.4 1.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ09510.1 - 6.2e-05 23.0 0.1 0.00016 21.7 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAJ09510.1 - 7e-05 22.6 0.7 7e-05 22.6 0.7 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ09510.1 - 8.1e-05 22.5 0.5 0.00023 21.1 0.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAJ09510.1 - 0.00014 21.5 5.2 0.00025 20.7 0.1 2.8 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OAJ09510.1 - 0.00074 19.1 0.9 0.0016 18.0 0.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ09510.1 - 0.0023 17.9 2.8 0.0024 17.8 0.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OAJ09510.1 - 0.063 13.5 2.9 0.95 9.7 2.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 OAJ09510.1 - 0.072 12.9 1.7 0.32 10.8 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RAP1 PF07218.11 OAJ09514.1 - 0.34 9.2 0.1 0.36 9.0 0.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TrkH PF02386.16 OAJ09515.1 - 3.8e-88 296.1 5.9 2e-85 287.2 1.9 2.1 2 0 0 2 2 2 2 Cation transport protein Sm_like PF16243.5 OAJ09518.1 - 0.044 13.9 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Sm_like domain TPR_2 PF07719.17 OAJ09531.1 - 5e-06 26.2 7.6 0.17 12.0 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ09531.1 - 2.5e-05 24.1 1.9 0.48 10.8 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ09531.1 - 0.00011 21.8 1.0 0.79 9.6 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ09531.1 - 0.00021 21.5 10.7 0.65 10.3 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ09531.1 - 0.00046 20.8 10.7 0.64 11.0 0.0 6.4 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ09531.1 - 0.013 16.1 0.0 11 7.0 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ09531.1 - 0.026 15.0 5.4 2.8 8.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ09531.1 - 0.029 14.2 6.6 19 5.3 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ09531.1 - 0.036 14.1 0.2 8.6 6.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ09531.1 - 0.072 12.8 1.6 18 5.1 0.1 3.9 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 OAJ09531.1 - 2.3 8.9 5.7 7.4 7.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PQ-loop PF04193.14 OAJ09566.1 - 2e-19 69.1 1.2 2e-19 69.1 1.2 1.5 2 0 0 2 2 2 1 PQ loop repeat RskA PF10099.9 OAJ09566.1 - 0.44 10.8 4.9 0.54 10.5 4.9 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ENTH PF01417.20 OAJ09568.1 - 3.4e-43 146.7 0.1 4.5e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAJ09568.1 - 0.0035 16.4 0.1 0.0051 15.8 0.1 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 OAJ09568.1 - 0.062 13.1 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 VHS domain Retrotrans_gag PF03732.17 OAJ09572.1 - 8.4e-11 42.0 0.2 1.7e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ09572.1 - 0.0026 17.8 0.8 0.0042 17.1 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAJ09572.1 - 0.004 17.0 0.0 0.009 15.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_6 PF15288.6 OAJ09572.1 - 0.085 12.7 0.6 0.18 11.6 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ09572.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peptidase_M17 PF00883.21 OAJ09589.1 - 1.1e-40 139.8 0.7 1.2e-40 139.7 0.7 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain AAA PF00004.29 OAJ09590.1 - 4.4e-07 30.4 0.0 7.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ09590.1 - 9.8e-06 26.1 0.2 4.2e-05 24.0 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OAJ09590.1 - 0.0027 17.7 0.1 0.024 14.6 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAJ09590.1 - 0.0094 15.7 0.2 0.016 15.0 0.2 1.6 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ09590.1 - 0.01 14.8 0.0 0.029 13.3 0.0 1.7 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 OAJ09590.1 - 0.03 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF853 PF05872.12 OAJ09590.1 - 0.044 12.4 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 OAJ09590.1 - 0.073 13.4 0.1 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ09590.1 - 0.073 12.8 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAJ09590.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OAJ09590.1 - 0.11 12.7 0.1 0.17 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ09590.1 - 0.13 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 OAJ09590.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_lid_9 PF17871.1 OAJ09591.1 - 2.1e-26 91.9 1.4 4e-26 90.9 0.7 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_2 PF07724.14 OAJ09591.1 - 3.6e-18 66.3 0.0 5.1e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAJ09591.1 - 0.00015 22.2 0.0 0.00068 20.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ09591.1 - 0.0017 18.1 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ09591.1 - 0.0028 17.7 0.0 0.017 15.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAJ09591.1 - 0.011 15.0 0.1 0.025 13.8 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_6 PF12774.7 OAJ09591.1 - 0.037 13.0 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Torsin PF06309.11 OAJ09591.1 - 0.041 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.12 OAJ09591.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 OAJ09591.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AIF_C PF14721.6 OAJ09591.1 - 0.41 11.0 1.4 1.5 9.2 1.4 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tmemb_cc2 PF10267.9 OAJ09594.1 - 0.026 13.7 7.2 0.028 13.6 7.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SYCE1 PF15233.6 OAJ09594.1 - 0.055 13.5 9.7 0.068 13.2 9.7 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 RRF PF01765.19 OAJ09594.1 - 0.091 12.7 3.3 0.085 12.8 2.2 1.5 1 1 0 1 1 1 0 Ribosome recycling factor Filament PF00038.21 OAJ09594.1 - 0.098 12.2 12.1 0.12 12.0 11.3 1.4 1 1 0 1 1 1 0 Intermediate filament protein Laminin_II PF06009.12 OAJ09594.1 - 0.1 12.6 8.3 0.13 12.3 8.3 1.1 1 0 0 1 1 1 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 OAJ09594.1 - 0.15 12.3 11.9 0.24 11.6 11.9 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 LPP20 PF02169.16 OAJ09594.1 - 0.54 10.6 3.5 0.9 9.9 3.5 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein OmpH PF03938.14 OAJ09594.1 - 0.8 10.0 14.3 1.1 9.6 14.3 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Spc34 PF08657.10 OAJ09594.1 - 0.81 9.4 6.8 1 9.1 6.8 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 Atg14 PF10186.9 OAJ09594.1 - 1 8.4 10.4 1.1 8.2 10.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 OAJ09594.1 - 1.6 7.9 6.7 1.7 7.8 6.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.13 OAJ09594.1 - 2.3 8.6 14.1 9 6.7 14.1 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.8 OAJ09594.1 - 2.3 5.6 15.5 2.6 5.4 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 OAJ09594.1 - 2.5 7.6 9.4 2.7 7.5 9.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 OAJ09594.1 - 2.6 8.6 6.2 6.8 7.2 6.2 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 Phage_Mu_Gam PF07352.12 OAJ09594.1 - 2.7 7.9 11.2 1.9 8.4 5.8 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein V-ATPase_G_2 PF16999.5 OAJ09594.1 - 2.9 8.4 22.0 25 5.3 22.0 2.2 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Ax_dynein_light PF10211.9 OAJ09594.1 - 4.9 7.1 13.2 8 6.4 5.3 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain RALF PF05498.11 OAJ09607.1 - 0.15 13.1 0.0 0.2 12.7 0.0 1.2 1 0 0 1 1 1 0 Rapid ALkalinization Factor (RALF) eIF3_subunit PF08597.10 OAJ09608.1 - 5.2e-48 164.1 28.1 5.9e-48 163.9 28.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDC45 PF02724.14 OAJ09608.1 - 0.075 11.3 14.4 0.11 10.7 14.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 OAJ09608.1 - 0.2 12.0 40.8 0.054 13.9 11.0 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp_protease_2 PF13650.6 OAJ09620.1 - 0.0018 18.9 0.0 0.0055 17.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09620.1 - 0.15 12.7 0.6 0.6 10.7 0.0 2.3 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 OAJ09622.1 - 2.9e-15 56.1 0.1 5.2e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09622.1 - 2.1e-14 53.3 0.0 5.4e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09622.1 - 4e-12 46.4 0.0 6.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ09622.1 - 2.9e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ09622.1 - 0.00086 19.6 0.0 0.0024 18.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ09622.1 - 0.039 14.2 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 H2C2 zinc finger Exc PF07825.11 OAJ09622.1 - 0.065 13.2 0.2 0.21 11.6 0.2 1.9 1 0 0 1 1 1 0 Excisionase-like protein CDC37_C PF08564.10 OAJ09627.1 - 1.5e-10 41.0 0.3 1.5e-10 41.0 0.3 1.1 1 0 0 1 1 1 1 Cdc37 C terminal domain UCH PF00443.29 OAJ09628.1 - 2.1e-13 50.4 0.2 2.3e-13 50.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.20 OAJ09628.1 - 0.011 16.1 1.3 0.021 15.1 0.6 1.8 2 0 0 2 2 2 0 Putative cell wall binding repeat SnoaL PF07366.12 OAJ09629.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase JmjC PF02373.22 OAJ09638.1 - 7.4e-17 61.8 4.2 1.9e-16 60.5 0.1 2.5 2 1 1 3 3 3 1 JmjC domain, hydroxylase TFIIA PF03153.13 OAJ09638.1 - 0.028 14.4 14.4 0.028 14.4 14.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 OAJ09638.1 - 0.11 12.5 1.7 0.19 11.8 1.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 OAJ09638.1 - 0.11 11.4 5.9 0.13 11.2 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RVT_1 PF00078.27 OAJ09650.1 - 8.2e-23 81.1 0.0 1.4e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09650.1 - 1.1e-20 73.5 0.1 2.5e-13 49.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09650.1 - 5.6e-15 55.5 0.0 1.1e-09 38.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09650.1 - 2.7e-13 49.8 0.0 5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09650.1 - 2.9e-11 43.6 0.0 7.3e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09650.1 - 0.011 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger HTH_Tnp_Tc5 PF03221.16 OAJ09657.1 - 1.1e-07 31.8 0.0 2.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 OAJ09657.1 - 1.6e-07 31.2 0.1 4.7e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease PXA PF02194.15 OAJ09657.1 - 0.17 11.8 4.3 0.4 10.6 4.2 1.7 1 1 0 1 1 1 0 PXA domain GREB1 PF15782.5 OAJ09657.1 - 6.8 3.7 9.5 8.8 3.3 9.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OAJ09657.1 - 7.5 4.7 18.4 12 4.1 18.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF659 PF04937.15 OAJ09663.1 - 0.0017 18.3 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DNA_pol_phi PF04931.13 OAJ09663.1 - 0.14 10.2 5.7 0.25 9.4 5.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi Retrotrans_gag PF03732.17 OAJ09683.1 - 8.1e-11 42.1 0.0 2.2e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ09683.1 - 8.1e-07 28.9 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Cupin_4 PF08007.12 OAJ09684.1 - 9.4e-05 22.0 0.1 0.00014 21.4 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 OAJ09684.1 - 0.075 13.5 0.2 0.19 12.2 0.0 1.7 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 OAJ09684.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin rve PF00665.26 OAJ09685.1 - 3.5e-16 59.4 0.0 5.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAJ09685.1 - 1e-07 31.7 0.2 2e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 OAJ09685.1 - 0.11 12.6 0.0 0.42 10.8 0.0 2.1 1 0 0 1 1 1 0 Integrase zinc binding domain DUF948 PF06103.11 OAJ09689.1 - 0.0044 17.3 1.1 0.053 13.8 0.2 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OAJ09689.1 - 0.0045 17.0 0.8 0.014 15.4 0.2 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 OAJ09689.1 - 0.57 10.3 7.5 2 8.5 7.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CorA PF01544.18 OAJ09689.1 - 0.84 8.9 8.7 0.26 10.6 2.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein H_lectin PF09458.10 OAJ09690.1 - 2.5e-10 40.4 0.1 2e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 H-type lectin domain DUF5344 PF17279.2 OAJ09702.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Corona_NS1 PF06145.11 OAJ09702.1 - 0.12 11.9 1.2 0.27 10.8 1.2 1.5 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 Spt5_N PF11942.8 OAJ09702.1 - 0.43 11.6 19.3 0.55 11.3 6.3 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Prefoldin_2 PF01920.20 OAJ09707.1 - 4.6e-17 61.9 7.7 5.8e-17 61.6 7.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 OAJ09707.1 - 0.026 14.7 0.8 0.026 14.7 0.8 2.0 2 0 0 2 2 2 0 Tropomyosin like FliD_C PF07195.12 OAJ09707.1 - 0.055 12.9 0.4 0.055 12.9 0.4 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Sec23_trunk PF04811.15 OAJ09707.1 - 0.071 12.7 0.9 0.12 11.9 0.9 1.3 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain DUF2408 PF10303.9 OAJ09707.1 - 0.072 13.7 2.6 0.093 13.3 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FTA4 PF13093.6 OAJ09707.1 - 0.16 11.9 6.9 0.63 9.9 6.8 2.0 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Coat_F PF07875.12 OAJ09707.1 - 0.4 10.9 2.3 8.1 6.8 0.3 2.7 2 1 1 3 3 3 0 Coat F domain Cep57_MT_bd PF06657.13 OAJ09707.1 - 7.9 7.0 9.1 10 6.7 3.9 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Pro_isomerase PF00160.21 OAJ09708.1 - 5.6e-48 163.2 0.0 1.6e-47 161.7 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAJ09708.1 - 8.5e-11 42.2 0.8 0.001 19.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09708.1 - 0.0025 18.1 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ09708.1 - 0.088 11.8 0.5 0.88 8.5 0.1 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nsp1_C PF05064.13 OAJ09717.1 - 0.047 13.5 6.4 1.4 8.7 1.3 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF724 PF05266.14 OAJ09717.1 - 0.12 12.1 8.9 0.15 11.8 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SOGA PF11365.8 OAJ09717.1 - 0.28 12.3 9.3 2.4 9.3 1.4 2.1 1 1 1 2 2 2 0 Protein SOGA Mucin_bdg PF03272.13 OAJ09717.1 - 0.74 9.9 5.7 5.2 7.1 0.3 2.2 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module Atg14 PF10186.9 OAJ09717.1 - 0.99 8.4 8.0 1.1 8.3 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CDI PF02234.19 OAJ09717.1 - 2.6 8.3 10.4 4.1 7.7 1.0 2.9 2 1 1 3 3 3 0 Cyclin-dependent kinase inhibitor Spc24 PF08286.11 OAJ09717.1 - 3.4 7.9 8.6 0.98 9.7 2.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2390 PF09523.10 OAJ09717.1 - 5.3 7.4 8.1 6.4 7.1 7.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2390) UPF0242 PF06785.11 OAJ09717.1 - 7.7 6.6 11.4 1.9 8.5 1.4 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus P66_CC PF16563.5 OAJ09718.1 - 0.08 12.6 0.8 0.18 11.5 0.8 1.6 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Lipase_3 PF01764.25 OAJ09723.1 - 9.7e-11 41.7 0.0 1.7e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ09723.1 - 0.0013 18.1 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ09723.1 - 0.014 16.0 0.1 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family RVT_1 PF00078.27 OAJ09733.1 - 2.9e-23 82.6 0.0 5e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09733.1 - 2.8e-14 53.0 0.4 5.4e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09733.1 - 6.3e-14 51.8 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09733.1 - 7.3e-11 42.3 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09733.1 - 0.0018 18.9 0.3 0.013 16.1 0.1 2.5 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ09733.1 - 0.0041 17.4 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ09733.1 - 0.012 16.2 0.1 0.053 14.1 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease C1q PF00386.21 OAJ09733.1 - 0.034 14.4 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 C1q domain Sox17_18_mid PF12067.8 OAJ09734.1 - 0.0011 19.0 0.2 0.0029 17.6 0.2 1.8 1 0 0 1 1 1 1 Sox 17/18 central domain bVLRF1 PF18826.1 OAJ09734.1 - 0.088 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor zf-B_box PF00643.24 OAJ09740.1 - 0.076 13.2 5.3 0.14 12.4 5.3 1.4 1 0 0 1 1 1 0 B-box zinc finger MRC1 PF09444.10 OAJ09745.1 - 7.4e-19 68.7 28.5 7.4e-19 68.7 28.5 7.4 7 1 1 8 8 8 1 MRC1-like domain RRM_1 PF00076.22 OAJ09746.1 - 9e-20 70.3 0.0 1.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 OAJ09746.1 - 7.1e-09 36.2 5.6 1.2e-08 35.5 5.6 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 OAJ09746.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 OAJ09746.1 - 0.17 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif tRNA_int_endo PF01974.17 OAJ09767.1 - 5.3e-18 64.9 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAJ09767.1 - 0.00052 19.6 0.4 0.0013 18.3 0.4 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain MitMem_reg PF13012.6 OAJ09768.1 - 3e-28 98.5 0.2 6.9e-28 97.3 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAJ09768.1 - 1.2e-14 54.3 0.0 2.4e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DAO PF01266.24 OAJ09769.1 - 1e-31 110.8 0.3 1.2e-31 110.6 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ09769.1 - 1.7e-06 27.5 0.1 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ09769.1 - 7.9e-06 26.3 0.2 0.027 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ09769.1 - 5e-05 23.4 0.3 9.4e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAJ09769.1 - 0.00087 18.2 1.6 0.19 10.5 0.2 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Mqo PF06039.15 OAJ09769.1 - 0.0016 17.1 0.0 1.2 7.6 0.0 2.0 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.6 OAJ09769.1 - 0.0032 16.7 0.0 0.066 12.3 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ09769.1 - 0.0042 17.1 0.2 0.045 13.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 OAJ09769.1 - 0.0053 16.1 0.4 0.56 9.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 OAJ09769.1 - 0.042 13.1 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 OAJ09769.1 - 0.051 12.4 0.2 0.15 10.8 0.1 1.7 2 0 0 2 2 2 0 MCRA family Sacchrp_dh_NADP PF03435.18 OAJ09769.1 - 0.073 13.3 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 OAJ09769.1 - 0.14 11.5 0.1 3 7.1 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase RVT_1 PF00078.27 OAJ09780.1 - 0.019 14.5 0.0 0.11 12.0 0.0 2.1 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ADH_zinc_N PF00107.26 OAJ09788.1 - 1.7e-16 60.4 0.6 2.6e-16 59.8 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ09788.1 - 2.2e-15 57.9 0.0 5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ09788.1 - 1e-06 28.6 0.2 8.6e-06 25.6 0.0 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain DAGK_cat PF00781.24 OAJ09788.1 - 0.014 15.0 0.2 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CMAS PF02353.20 OAJ09788.1 - 0.025 13.9 0.1 0.085 12.1 0.1 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase ELFV_dehydrog PF00208.21 OAJ09788.1 - 0.07 12.8 0.3 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SOG2 PF10428.9 OAJ09791.1 - 4.1 6.5 16.6 5.3 6.1 16.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NDC10_II PF16787.5 OAJ09794.1 - 3.1e-53 180.9 0.0 4.7e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ09794.1 - 1.2e-08 35.1 0.0 3.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sporozoite_P67 PF05642.11 OAJ09794.1 - 0.12 10.4 2.8 0.21 9.6 2.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_10 PF13374.6 OAJ09800.1 - 1e-26 91.9 49.9 0.00027 20.7 0.6 14.4 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ09800.1 - 6.1e-21 74.5 57.5 0.0013 19.0 0.1 12.6 6 4 5 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ09800.1 - 5.7e-14 51.0 24.8 0.22 11.7 0.2 13.0 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ09800.1 - 3.1e-11 42.6 7.3 16 5.5 0.0 11.4 12 1 1 13 13 13 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ09800.1 - 3.8e-06 27.0 22.3 0.015 15.4 0.2 6.7 4 1 1 7 7 7 4 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 OAJ09800.1 - 4.5e-06 26.6 9.8 0.37 10.9 0.0 6.9 6 2 1 8 8 8 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 OAJ09800.1 - 2.3e-05 24.3 14.2 0.98 9.8 0.0 9.3 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ09800.1 - 0.0025 18.3 11.0 28 5.7 0.0 8.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Phage-MuB_C PF09077.11 OAJ09800.1 - 0.1 12.5 0.3 21 5.1 0.1 3.7 4 0 0 4 4 4 0 Mu B transposition protein, C terminal TPR_7 PF13176.6 OAJ09800.1 - 0.33 11.1 29.4 3.9 7.7 0.2 9.6 11 0 0 11 11 11 0 Tetratricopeptide repeat rve PF00665.26 OAJ09808.1 - 6.3e-17 61.9 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ09808.1 - 9.3e-16 57.7 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ09808.1 - 6e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ09808.1 - 1.7e-05 24.7 9.1 0.029 14.4 2.2 2.7 2 0 0 2 2 2 2 Zinc knuckle rve_3 PF13683.6 OAJ09808.1 - 3.8e-05 23.4 0.1 0.004 16.9 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-C2H2_10 PF16588.5 OAJ09808.1 - 1.8 8.3 4.3 0.72 9.6 1.4 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger RVT_2 PF07727.14 OAJ09809.1 - 2.5e-61 207.4 0.0 3e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_32C PF08244.12 OAJ09820.1 - 3.1e-05 24.0 0.0 3.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal YAF2_RYBP PF17219.3 OAJ09820.1 - 1.7 8.3 3.5 26 4.5 0.0 2.7 3 0 0 3 3 3 0 Yaf2/RYBP C-terminal binding motif ABC_membrane PF00664.23 OAJ09829.1 - 8.6e-45 153.5 39.0 2.5e-29 102.8 12.1 3.8 3 1 1 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ09829.1 - 2.7e-41 141.3 0.0 1.1e-26 93.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ09829.1 - 1.4e-09 37.8 3.7 0.00024 20.6 0.1 4.4 3 2 1 5 5 5 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ09829.1 - 1.6e-05 25.2 0.2 2.2 8.5 0.1 3.8 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 OAJ09829.1 - 0.00012 22.7 0.6 0.25 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 OAJ09829.1 - 0.00081 19.8 0.2 1.7 9.1 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ09829.1 - 0.0035 17.7 0.7 0.12 12.8 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 OAJ09829.1 - 0.0065 16.3 0.2 6.6 6.4 0.0 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ09829.1 - 0.0077 15.9 1.5 5.3 6.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ09829.1 - 0.031 14.0 0.0 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAJ09829.1 - 0.034 14.1 0.8 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 OAJ09829.1 - 0.035 13.8 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ09829.1 - 0.04 14.1 1.0 10 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ09829.1 - 0.042 13.4 0.6 2.2 7.8 0.2 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OAJ09829.1 - 0.095 12.7 0.2 0.93 9.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OAJ09829.1 - 0.11 12.4 0.3 16 5.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 OAJ09829.1 - 0.13 11.2 0.2 0.27 10.2 0.2 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 OAJ09829.1 - 0.14 12.2 0.8 0.38 10.8 0.8 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 OAJ09829.1 - 0.15 12.5 0.1 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 OAJ09829.1 - 0.16 11.7 3.3 3.7 7.2 0.6 3.4 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 OAJ09829.1 - 0.31 10.9 1.8 8.1 6.3 0.3 2.9 2 0 0 2 2 2 0 NACHT domain Orthoreo_P10 PF07204.11 OAJ09829.1 - 0.36 10.8 1.8 3.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 AAA_18 PF13238.6 OAJ09829.1 - 1.2 9.7 3.1 20 5.7 0.0 3.3 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 OAJ09829.1 - 4.6 6.8 5.3 1.9 8.1 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RVT_1 PF00078.27 OAJ09843.1 - 7.7e-25 87.7 0.0 1.3e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09843.1 - 3.4e-15 55.9 0.0 6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09843.1 - 1.2e-14 54.2 0.0 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09843.1 - 9.5e-08 32.3 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09843.1 - 0.00062 19.9 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ09843.1 - 0.012 15.8 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase AMP-binding PF00501.28 OAJ09848.1 - 2e-137 458.3 2.2 4.8e-69 233.0 0.4 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 OAJ09848.1 - 6.3e-54 183.4 0.0 4.2e-41 141.1 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 OAJ09848.1 - 3.5e-09 36.9 0.0 1.4e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ09848.1 - 4.7e-06 27.5 0.0 1.5e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_tranf_2_3 PF13641.6 OAJ09848.1 - 0.072 13.0 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 Glycosyltransferase like family 2 IMPDH PF00478.25 OAJ09848.1 - 0.45 9.5 2.3 0.54 9.2 0.3 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF3678 PF12435.8 OAJ09848.1 - 2.5 7.6 5.1 0.47 9.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DnaJ PF00226.31 OAJ09856.1 - 2e-09 37.4 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain NdhM PF10664.9 OAJ09856.1 - 0.038 14.3 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M SPRR2 PF14820.6 OAJ09856.1 - 6.9 6.8 12.8 2.5 8.3 4.9 2.3 2 0 0 2 2 2 0 Small proline-rich 2 DnaJ PF00226.31 OAJ09857.1 - 3e-10 40.1 0.0 3e-10 40.1 0.0 3.1 3 1 2 5 5 5 1 DnaJ domain EPSP_synthase PF00275.20 OAJ09873.1 - 7.9e-111 370.7 0.0 1.3e-110 370.0 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAJ09873.1 - 4.7e-97 324.2 0.0 1.4e-96 322.7 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAJ09873.1 - 1.6e-39 136.5 0.0 3.3e-39 135.5 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAJ09873.1 - 2.8e-25 88.4 0.0 1.8e-24 85.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAJ09873.1 - 2.1e-20 73.4 0.0 5.1e-19 68.9 0.0 2.8 2 1 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 OAJ09873.1 - 1.1e-10 41.1 0.1 4.8e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAJ09873.1 - 4.6e-05 23.5 0.0 9.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 OAJ09873.1 - 6.9e-05 22.7 1.1 0.00029 20.6 1.1 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Asparaginase_C PF17763.1 OAJ09873.1 - 0.034 14.4 0.0 0.095 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain RVT_2 PF07727.14 OAJ09880.1 - 9.5e-61 205.5 0.0 1.2e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ09881.1 - 5.9e-05 22.7 0.1 7.6e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Utp14 PF04615.13 OAJ09894.1 - 3.3e-98 330.2 40.3 3.3e-98 330.2 40.3 2.3 1 1 1 2 2 2 1 Utp14 protein RhlB PF12300.8 OAJ09907.1 - 0.084 13.0 0.4 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Pex14_N PF04695.13 OAJ09907.1 - 0.76 10.4 6.9 0.081 13.6 0.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MetOD2 PF18548.1 OAJ09908.1 - 0.08 13.1 0.2 0.31 11.2 0.2 1.9 1 0 0 1 1 1 0 Metanogen output domain 2 MULE PF10551.9 OAJ09913.1 - 6.5e-07 29.7 0.0 2.7e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 OAJ09913.1 - 0.018 15.8 0.4 0.05 14.3 0.1 1.9 2 0 0 2 2 2 0 FAR1 DNA-binding domain SWIM PF04434.17 OAJ09914.1 - 0.091 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 SWIM zinc finger Annexin_like PF18411.1 OAJ09915.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Annexin-like domain KGG PF10685.9 OAJ09916.1 - 1.2e-08 34.9 9.6 8.3e-07 29.1 0.3 4.0 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif NOA36 PF06524.12 OAJ09916.1 - 1 8.6 5.8 1.2 8.4 5.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ09916.1 - 7.8 4.5 6.0 9 4.3 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi TIM21 PF08294.11 OAJ09925.1 - 0.42 10.5 2.4 0.25 11.2 0.5 1.7 2 0 0 2 2 2 0 TIM21 DUF202 PF02656.15 OAJ09925.1 - 3.3 8.2 6.1 3.1 8.3 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF89 PF01937.19 OAJ09930.1 - 1.1e-20 73.9 0.1 1.4e-20 73.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 rve PF00665.26 OAJ09934.1 - 2.2e-06 27.9 0.0 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ09934.1 - 5.6e-06 26.6 0.2 1.5e-05 25.2 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09934.1 - 0.0083 16.2 0.3 0.016 15.3 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain DUF2268 PF10026.9 OAJ09934.1 - 0.16 11.6 1.6 0.15 11.6 0.3 1.6 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) BUD22 PF09073.10 OAJ09938.1 - 0.00067 19.1 23.5 0.0012 18.3 23.5 1.4 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 OAJ09938.1 - 0.0078 14.5 18.1 0.01 14.1 18.1 1.2 1 0 0 1 1 1 1 Nop14-like family DARPP-32 PF05395.12 OAJ09938.1 - 0.0082 16.4 11.0 0.017 15.4 11.0 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 SDA1 PF05285.12 OAJ09938.1 - 0.014 14.8 18.7 0.021 14.3 18.7 1.3 1 0 0 1 1 1 0 SDA1 Myb_DNA-bind_6 PF13921.6 OAJ09938.1 - 0.11 12.7 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain CDC45 PF02724.14 OAJ09938.1 - 0.2 9.9 13.0 0.26 9.5 13.0 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 OAJ09938.1 - 0.37 9.3 36.2 0.66 8.5 36.2 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3138 PF11336.8 OAJ09938.1 - 0.48 9.0 1.4 0.69 8.5 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Zip PF02535.22 OAJ09938.1 - 2 7.6 4.0 2.6 7.2 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 OAJ09938.1 - 5.6 5.9 19.2 8.8 5.2 19.2 1.3 1 0 0 1 1 1 0 Paf1 Peptidase_M18 PF02127.15 OAJ09941.1 - 7.6e-160 532.4 0.0 8.8e-160 532.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OAJ09941.1 - 0.00068 18.7 0.0 0.095 11.7 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.23 OAJ09942.1 - 3.3e-17 62.8 0.6 5e-17 62.2 0.6 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4149 PF13664.6 OAJ09942.1 - 0.17 12.2 2.2 0.37 11.1 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Sec15 PF04091.12 OAJ09947.1 - 5.6e-83 278.9 0.0 2.1e-82 277.1 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 OAJ09947.1 - 1.6e-05 24.8 3.8 1.7e-05 24.8 0.1 3.0 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 OAJ09947.1 - 0.00093 19.2 0.1 0.0078 16.3 0.0 2.6 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 OAJ09947.1 - 0.0029 17.8 3.9 0.012 15.8 0.1 3.3 3 1 0 3 3 3 1 Golgi transport complex subunit 5 MnmE_helical PF12631.7 OAJ09947.1 - 0.0029 17.8 0.8 5 7.2 1.0 3.8 3 1 0 3 3 3 1 MnmE helical domain COG2 PF06148.11 OAJ09947.1 - 0.017 15.2 3.7 0.028 14.5 0.7 2.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 OAJ09947.1 - 0.081 12.7 1.3 0.19 11.5 0.1 2.3 3 0 0 3 3 3 0 Exocyst complex component Sec5 CENP-F_leu_zip PF10473.9 OAJ09947.1 - 0.12 12.4 2.3 0.54 10.3 0.0 3.2 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PALP PF00291.25 OAJ09948.1 - 2.8e-79 266.6 0.1 5.6e-79 265.6 0.1 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAJ09948.1 - 4.5e-22 77.6 0.1 4.3e-12 45.6 0.0 4.4 4 1 1 5 5 5 3 C-terminal regulatory domain of Threonine dehydratase RVT_1 PF00078.27 OAJ09958.1 - 1.8e-23 83.2 0.0 2.7e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09959.1 - 4.4e-21 74.8 0.0 1.1e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09959.1 - 2.1e-15 56.9 0.0 9.6e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09959.1 - 1.7e-14 53.7 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09959.1 - 1.3e-12 47.9 0.0 3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain ATG16 PF08614.11 OAJ09960.1 - 0.027 14.7 1.5 0.027 14.7 1.5 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) SSFA2_C PF14723.6 OAJ09964.1 - 1.3 8.9 4.3 1.9 8.4 4.3 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus PCI PF01399.27 OAJ09970.1 - 2.7e-06 27.8 0.0 4.9e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 PCI domain LRR_6 PF13516.6 OAJ09971.1 - 0.34 11.1 6.0 2.1e+02 2.4 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich repeat DUF1765 PF08578.10 OAJ09975.1 - 1.4e-27 96.7 1.3 2.5e-27 95.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) RVT_1 PF00078.27 OAJ09977.1 - 1.9e-10 40.7 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEC-1_N PF04625.13 OAJ09977.1 - 4.3 6.2 8.7 8 5.4 8.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M17 PF00883.21 OAJ09984.1 - 1.9e-111 372.3 0.2 2.5e-111 371.9 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OAJ09984.1 - 1.2e-07 31.6 0.1 2.5e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain NUC153 PF08159.12 OAJ09985.1 - 1.8e-10 40.4 0.3 3.2e-10 39.6 0.3 1.4 1 0 0 1 1 1 1 NUC153 domain CDC45 PF02724.14 OAJ09985.1 - 0.46 8.7 9.8 0.74 8.0 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ09985.1 - 0.62 8.2 20.7 0.89 7.7 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OAJ09985.1 - 3.3 7.6 11.7 5 7.0 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Apt1 PF10351.9 OAJ09985.1 - 6.3 5.5 10.8 11 4.7 10.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 OAJ09985.1 - 7.7 4.5 16.6 12 3.9 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apolipoprotein PF01442.18 OAJ10012.1 - 0.03 14.2 2.2 0.07 13.0 2.2 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Filament PF00038.21 OAJ10012.1 - 0.057 13.0 0.3 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Intermediate filament protein RVT_1 PF00078.27 OAJ10013.1 - 9e-23 80.9 0.0 2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10013.1 - 5.2e-20 71.3 0.0 1e-13 51.2 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10013.1 - 1.1e-15 57.4 0.3 2.1e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10013.1 - 4.2e-14 52.7 0.0 3.4e-08 33.7 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10013.1 - 6e-10 39.3 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10013.1 - 0.00016 21.8 0.1 0.00061 19.9 0.1 2.1 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 OAJ10013.1 - 0.0045 17.6 0.1 0.014 16.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10013.1 - 0.026 15.1 0.0 0.091 13.3 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Exc PF07825.11 OAJ10013.1 - 0.098 12.7 0.2 0.37 10.8 0.2 2.0 1 0 0 1 1 1 0 Excisionase-like protein TPR_1 PF00515.28 OAJ10020.1 - 9.2e-06 25.3 0.7 2.2 8.2 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10020.1 - 0.001 19.0 10.0 2.2 8.6 0.1 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ10020.1 - 0.0025 18.3 3.7 5.3 7.6 0.2 5.9 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ10020.1 - 0.0076 16.4 1.4 28 5.2 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ10020.1 - 0.05 13.5 1.8 13 5.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ10020.1 - 0.059 13.7 9.9 3.3 8.1 0.1 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF2585 PF10755.9 OAJ10020.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) TPR_14 PF13428.6 OAJ10020.1 - 0.31 12.0 10.1 17 6.6 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ10020.1 - 0.32 11.1 3.6 11 6.4 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat F-box PF00646.33 OAJ10021.1 - 1.8e-06 27.6 0.2 3.1e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ10021.1 - 0.00053 19.8 0.3 0.0011 18.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ10021.1 - 0.0006 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 F-box cNMP_binding PF00027.29 OAJ10033.1 - 1e-38 131.2 0.1 4.3e-19 68.4 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAJ10033.1 - 3.6e-13 48.9 0.3 6.6e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Glyco_hydro_30 PF02055.16 OAJ10034.1 - 3.3e-19 69.1 0.0 1.9e-18 66.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAJ10034.1 - 0.0078 15.5 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 59 VID27 PF08553.10 OAJ10039.1 - 2e-154 513.9 0.1 2.8e-154 513.5 0.1 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAJ10039.1 - 8.2e-35 120.2 0.1 8.2e-35 120.2 0.1 3.8 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 OAJ10039.1 - 1.7e-25 89.4 1.9 3.9e-25 88.3 1.9 1.6 1 0 0 1 1 1 1 VID27 PH-like domain A_deaminase PF00962.22 OAJ10039.1 - 0.12 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Nucleo_P87 PF07267.11 OAJ10039.1 - 3.2 6.5 6.3 6.8 5.4 6.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_Rpb2_6 PF00562.28 OAJ10040.1 - 6.5e-50 170.3 0.1 8.3e-48 163.4 0.7 2.0 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 EphA2_TM PF14575.6 OAJ10050.1 - 0.00066 20.5 0.0 0.054 14.4 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OAJ10050.1 - 0.011 16.0 0.3 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) CcmD PF04995.14 OAJ10050.1 - 0.017 15.2 6.2 3.6 7.7 3.5 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF347 PF03988.12 OAJ10050.1 - 0.045 13.9 1.0 3.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CD34_antigen PF06365.12 OAJ10050.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DPBB_1 PF03330.18 OAJ10055.1 - 6.6e-05 23.1 0.1 0.00015 21.9 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Menin PF05053.13 OAJ10055.1 - 0.0022 16.4 8.2 0.015 13.7 8.6 1.8 2 0 0 2 2 2 1 Menin SOG2 PF10428.9 OAJ10055.1 - 0.22 10.7 15.5 0.3 10.2 15.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 OAJ10055.1 - 1 8.1 14.1 1.3 7.8 14.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 OAJ10055.1 - 1.4 7.8 8.9 1.8 7.5 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Cupin_1 PF00190.22 OAJ10056.1 - 4.5e-07 29.6 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAJ10056.1 - 6.6e-05 22.6 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain SKG6 PF08693.10 OAJ10072.1 - 9.4e-10 37.7 1.5 9.4e-10 37.7 1.5 3.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAJ10072.1 - 0.00018 21.4 0.1 0.00056 19.8 0.1 1.8 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 OAJ10072.1 - 0.031 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DAG1 PF05454.11 OAJ10072.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RIFIN PF02009.16 OAJ10072.1 - 0.13 12.2 0.1 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Rifin EphA2_TM PF14575.6 OAJ10072.1 - 0.17 12.7 0.0 1.1 10.2 0.0 2.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4366 PF14283.6 OAJ10072.1 - 0.34 11.0 1.6 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF202 PF02656.15 OAJ10072.1 - 0.5 10.8 2.7 6.6 7.3 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Roughex PF06020.11 OAJ10072.1 - 1 8.4 7.7 0.24 10.5 3.2 1.9 2 0 0 2 2 2 0 Drosophila roughex protein SARAF PF06682.12 OAJ10072.1 - 1.1 8.9 13.1 0.015 15.0 4.1 2.5 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 OAJ10072.1 - 1.9 8.3 9.5 0.069 12.9 1.9 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Sedlin_N PF04628.13 OAJ10073.1 - 3.5e-19 69.2 0.0 8.9e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region ATG16 PF08614.11 OAJ10079.1 - 0.025 14.8 1.3 0.025 14.8 1.3 2.3 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) IL2 PF00715.17 OAJ10079.1 - 0.18 11.8 0.1 1.2 9.1 0.1 2.2 1 1 0 1 1 1 0 Interleukin 2 SKA1 PF07160.12 OAJ10079.1 - 0.72 9.7 2.2 1.1 9.0 1.2 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 RVT_1 PF00078.27 OAJ10080.1 - 1.4e-23 83.6 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10080.1 - 9.3e-21 73.7 0.0 1.1e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10080.1 - 1.5e-14 54.2 0.0 3.3e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10080.1 - 1.5e-14 53.8 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10080.1 - 6.6e-05 23.1 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10080.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Asp_protease_2 PF13650.6 OAJ10081.1 - 0.012 16.3 0.0 0.021 15.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Atx10homo_assoc PF09759.9 OAJ10088.1 - 2.6e-18 65.9 0.0 8.9e-18 64.1 0.0 2.0 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Med31 PF05669.12 OAJ10089.1 - 6.5e-28 96.6 0.0 7.9e-28 96.3 0.0 1.1 1 0 0 1 1 1 1 SOH1 CAP_N PF01213.19 OAJ10089.1 - 5.2 6.5 5.1 6.3 6.2 5.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MCM2_N PF12619.8 OAJ10090.1 - 0.2 11.9 6.2 0.51 10.6 6.2 1.6 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 TPR_12 PF13424.6 OAJ10101.1 - 1.3e-09 38.2 13.6 2.9e-06 27.5 5.2 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ10101.1 - 4.7e-09 35.8 12.7 1.8e-05 24.4 0.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10101.1 - 0.00034 20.5 7.1 0.056 13.6 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ10101.1 - 0.004 17.2 0.3 0.0085 16.2 0.3 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 OAJ10101.1 - 0.011 15.5 0.9 2.3 8.2 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ10101.1 - 0.016 15.4 1.2 0.94 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ10101.1 - 0.074 13.7 8.2 17 6.2 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2052 PF09747.9 OAJ10101.1 - 0.09 12.9 0.7 0.16 12.1 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TPR_4 PF07721.14 OAJ10101.1 - 0.18 12.5 12.0 1.4 9.7 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ10101.1 - 0.28 11.3 3.0 13 5.9 0.1 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Csm1_N PF18504.1 OAJ10101.1 - 2.4 8.5 5.1 1.8 9.0 2.4 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain TPR_14 PF13428.6 OAJ10101.1 - 6.3 7.9 13.6 6.3 7.9 0.4 4.5 2 1 2 4 4 3 0 Tetratricopeptide repeat Choline_transpo PF04515.12 OAJ10102.1 - 5.3e-53 180.3 5.8 7.6e-53 179.8 2.2 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter Pox_A12 PF04651.13 OAJ10102.1 - 0.26 11.3 1.1 0.45 10.6 1.1 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein LIP PF03583.14 OAJ10103.1 - 3.6e-40 138.1 0.0 4.2e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ10103.1 - 0.00051 19.6 0.1 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ10103.1 - 0.0062 15.8 0.1 0.91 8.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ10103.1 - 0.027 14.1 0.2 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold HTH_33 PF13592.6 OAJ10110.1 - 2e-06 27.3 0.1 3.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ10110.1 - 0.0004 20.9 0.4 0.0029 18.2 0.0 2.3 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 OAJ10110.1 - 0.0067 16.6 0.5 0.37 11.1 0.0 2.2 2 0 0 2 2 2 1 Transposase Arg_repressor PF01316.21 OAJ10110.1 - 0.0079 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain Serum_albumin PF00273.20 OAJ10110.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Serum albumin family DUF3410 PF11890.8 OAJ10110.1 - 0.12 12.1 1.6 0.19 11.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) HTH_11 PF08279.12 OAJ10110.1 - 0.24 11.4 1.9 0.62 10.1 0.1 2.4 3 0 0 3 3 3 0 HTH domain Ribosomal_L37e PF01907.19 OAJ10118.1 - 0.74 10.0 2.5 1.5 9.1 2.5 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e RVT_1 PF00078.27 OAJ10119.1 - 2.8e-20 72.8 0.0 4.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10119.1 - 5.6e-15 55.2 0.1 1.2e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ10119.1 - 1.6e-14 53.7 0.0 3.3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10119.1 - 5.2e-11 42.8 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ10119.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10120.1 - 5.9e-12 45.8 0.0 8.5e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10120.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribosomal_L15e PF00827.17 OAJ10126.1 - 1.5e-56 191.1 1.1 2.3e-56 190.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L5e PF17144.4 OAJ10126.1 - 4.4e-55 186.1 0.0 6.3e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAJ10126.1 - 1.9e-05 25.5 0.3 5.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region OrsD PF12013.8 OAJ10128.1 - 0.00097 19.6 0.2 0.002 18.6 0.2 1.5 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Pkinase PF00069.25 OAJ10135.1 - 2e-42 145.4 0.0 2.8e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10135.1 - 4.3e-18 65.5 0.0 6.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.6 OAJ10135.1 - 7.2e-09 35.8 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain Kinase-like PF14531.6 OAJ10135.1 - 6e-05 22.5 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ10135.1 - 0.0033 16.8 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ10135.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Dimer_Tnp_hAT PF05699.14 OAJ10136.1 - 3.8e-16 58.6 0.0 5.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-FokI_C PF09254.11 OAJ10136.1 - 0.0057 15.9 0.0 0.0093 15.2 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease FokI, C terminal DDE_Tnp_4 PF13359.6 OAJ10142.1 - 1.3e-15 57.4 0.0 1.9e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_3 PF12776.7 OAJ10149.1 - 1.9e-09 38.4 1.8 3.4e-09 37.5 1.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Sporozoite_P67 PF05642.11 OAJ10149.1 - 0.11 10.6 3.2 0.13 10.3 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 OAJ10149.1 - 0.5 8.6 4.3 0.49 8.6 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAJ10149.1 - 0.69 8.4 3.3 0.8 8.2 3.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Kri1_C PF12936.7 OAJ10161.1 - 3.4e-23 81.6 0.1 3.4e-23 81.6 0.1 5.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 OAJ10161.1 - 3.5e-20 72.5 15.4 3.5e-20 72.5 15.4 8.0 5 3 2 7 7 7 2 KRI1-like family NIF PF03031.18 OAJ10162.1 - 4.6e-50 169.4 0.0 2.9e-49 166.8 0.0 2.1 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase PAT1 PF09770.9 OAJ10162.1 - 1 7.6 12.4 1.2 7.3 12.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.7 OAJ10162.1 - 2.5 7.8 10.6 3.9 7.2 10.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit E_Pc_C PF06752.12 OAJ10162.1 - 3.1 7.8 11.9 6.7 6.8 11.9 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Homoserine_dh PF00742.19 OAJ10163.1 - 1.2e-46 158.8 0.0 1.8e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAJ10163.1 - 5e-17 62.6 0.1 9.3e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Ribosomal_L29 PF00831.23 OAJ10169.1 - 3.8e-19 68.4 3.4 3.8e-19 68.4 3.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein VirB8 PF04335.13 OAJ10169.1 - 0.028 14.3 0.3 0.03 14.2 0.3 1.1 1 0 0 1 1 1 0 VirB8 protein HTH_12 PF08461.10 OAJ10169.1 - 0.076 13.0 1.1 0.22 11.5 0.3 2.2 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain RRM_1 PF00076.22 OAJ10170.1 - 0.0035 17.1 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OAJ10171.1 - 1.3e-06 29.0 1.6 0.023 15.6 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PRP38_assoc PF12871.7 OAJ10171.1 - 1 10.0 10.2 1.8 9.2 1.3 3.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAD_binding_4 PF01565.23 OAJ10183.1 - 5.2e-19 68.4 0.6 1.4e-18 66.9 0.6 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ10183.1 - 0.0044 17.1 0.6 0.012 15.7 0.6 1.8 1 0 0 1 1 1 1 Berberine and berberine like Slx4 PF09494.10 OAJ10184.1 - 1.7e-09 37.4 0.1 1e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Slx4 endonuclease MFS_1 PF07690.16 OAJ10185.1 - 1.2e-27 96.7 25.0 1.2e-27 96.7 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ10185.1 - 7e-07 28.5 8.7 7e-07 28.5 8.7 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ10185.1 - 0.02 13.3 6.5 0.041 12.3 6.5 1.5 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Pil1 PF13805.6 OAJ10191.1 - 3.8e-50 170.9 0.1 6.4e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 DUF747 PF05346.11 OAJ10192.1 - 6.1e-112 374.2 1.2 1.2e-97 327.3 0.2 2.4 3 0 0 3 3 3 2 Eukaryotic membrane protein family GCOM2 PF15328.6 OAJ10196.1 - 7.5 6.9 7.1 12 6.2 7.1 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Dickkopf_N PF04706.12 OAJ10198.1 - 0.12 12.9 0.2 0.12 12.9 0.2 10.1 6 3 1 7 7 7 0 Dickkopf N-terminal cysteine-rich region SOG2 PF10428.9 OAJ10198.1 - 6.1 5.9 23.4 8.4 5.5 23.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RVT_1 PF00078.27 OAJ10209.1 - 6.2e-24 84.7 0.0 1.1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10209.1 - 7.8e-20 70.8 0.0 6.1e-13 48.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10209.1 - 2.8e-15 56.2 0.0 5.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10209.1 - 4.7e-13 49.3 0.0 3.1e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10209.1 - 2.4e-10 40.6 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10209.1 - 6.8e-05 23.4 0.1 0.00025 21.6 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10209.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ10209.1 - 0.15 12.3 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger TFIID_30kDa PF03540.13 OAJ10216.1 - 3.6e-08 33.2 0.0 9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 OAJ10216.1 - 9.2e-06 26.0 0.0 0.0044 17.4 0.0 2.6 3 0 0 3 3 3 2 CBS domain MIP PF00230.20 OAJ10217.1 - 1.2e-46 159.2 15.0 1.6e-46 158.9 15.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein STT3 PF02516.14 OAJ10217.1 - 0.31 9.9 12.3 0.19 10.6 8.9 2.0 1 1 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit DUF1289 PF06945.13 OAJ10231.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Methyltransf_16 PF10294.9 OAJ10232.1 - 2.1e-06 27.6 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAJ10232.1 - 0.0024 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAJ10232.1 - 0.0027 18.4 0.1 0.021 15.5 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ10232.1 - 0.051 14.2 0.1 0.19 12.4 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ10232.1 - 0.051 13.4 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Thioredoxin PF00085.20 OAJ10233.1 - 4.4e-60 200.1 0.2 3.9e-27 94.3 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 OAJ10233.1 - 1.4e-39 135.9 0.0 7.3e-34 117.3 0.1 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ10233.1 - 1.9e-12 47.3 0.1 0.02 15.2 0.0 4.5 4 1 0 4 4 4 3 Thioredoxin-like Calsequestrin PF01216.17 OAJ10233.1 - 2.4e-12 46.6 0.3 6.8e-12 45.1 0.1 1.7 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.6 OAJ10233.1 - 1.7e-11 44.5 1.1 0.044 14.2 0.1 4.7 4 1 0 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ10233.1 - 7.2e-07 29.2 0.7 0.01 15.7 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 OAJ10233.1 - 1.4e-06 28.3 0.0 0.0042 17.2 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 OAJ10233.1 - 0.00011 21.6 0.1 7.3 5.8 0.0 3.9 1 1 1 4 4 4 2 OST3 / OST6 family, transporter family Redoxin PF08534.10 OAJ10233.1 - 0.0003 20.5 1.2 6.1 6.6 0.0 3.6 3 0 0 3 3 3 2 Redoxin Glutaredoxin PF00462.24 OAJ10233.1 - 0.011 15.9 0.4 13 6.1 0.0 3.9 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_4 PF13462.6 OAJ10233.1 - 0.017 15.3 1.9 6.9 6.8 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin ERp29_N PF07912.13 OAJ10233.1 - 0.044 13.9 0.0 2 8.6 0.0 3.0 3 0 0 3 3 3 0 ERp29, N-terminal domain TraF PF13728.6 OAJ10233.1 - 0.21 11.3 5.1 4.3 7.1 0.0 3.7 4 1 1 5 5 4 0 F plasmid transfer operon protein Sua5_yciO_yrdC PF01300.18 OAJ10235.1 - 9.3e-39 132.8 0.1 3.9e-38 130.7 0.0 2.0 2 1 0 2 2 2 1 Telomere recombination GAS PF13851.6 OAJ10242.1 - 0.00047 19.6 9.6 0.00065 19.1 9.6 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4268 PF14088.6 OAJ10242.1 - 0.0021 18.0 0.6 0.0026 17.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4268) SHE3 PF17078.5 OAJ10242.1 - 0.0035 17.1 3.5 0.0048 16.6 3.5 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 OAJ10242.1 - 0.0065 15.4 12.2 0.0084 15.0 11.9 1.4 1 1 0 1 1 1 1 Spc7 kinetochore protein DivIC PF04977.15 OAJ10242.1 - 0.0078 16.0 11.9 0.28 11.0 5.4 2.3 1 1 0 2 2 2 2 Septum formation initiator TMF_TATA_bd PF12325.8 OAJ10242.1 - 0.015 15.5 14.8 0.16 12.2 1.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Med28 PF11594.8 OAJ10242.1 - 0.025 14.6 0.3 0.039 14.0 0.3 1.5 1 1 0 1 1 1 0 Mediator complex subunit 28 KxDL PF10241.9 OAJ10242.1 - 0.048 13.9 2.8 0.27 11.5 1.0 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein Mod_r PF07200.13 OAJ10242.1 - 0.064 13.4 9.9 2.5 8.2 5.5 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 OAJ10242.1 - 0.067 13.3 17.1 0.1 12.7 17.1 1.4 1 1 0 1 1 1 0 Tropomyosin like ZapB PF06005.12 OAJ10242.1 - 0.12 12.8 14.9 1.1 9.8 6.1 2.4 1 1 0 2 2 2 0 Cell division protein ZapB NPV_P10 PF05531.12 OAJ10242.1 - 0.13 12.7 0.4 4.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 OAJ10242.1 - 0.15 12.1 8.6 2.4 8.3 0.1 2.7 2 1 1 3 3 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 OAJ10242.1 - 0.21 11.6 13.4 0.3 11.1 1.7 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 OAJ10242.1 - 0.26 11.7 2.6 1.8 9.0 0.1 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 OAJ10242.1 - 0.34 11.6 8.2 1.3 9.6 3.2 2.1 1 1 0 2 2 2 0 Initiation control protein YabA DUF2968 PF11180.8 OAJ10242.1 - 0.49 10.0 13.5 0.36 10.5 9.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) CASP_C PF08172.12 OAJ10242.1 - 0.62 9.4 10.4 1.1 8.6 7.9 2.0 1 1 1 2 2 2 0 CASP C terminal DUF1640 PF07798.11 OAJ10242.1 - 0.67 10.0 11.3 3.1 7.8 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) GrpE PF01025.19 OAJ10242.1 - 0.9 9.2 13.3 2 8.1 5.7 2.1 2 0 0 2 2 2 0 GrpE HALZ PF02183.18 OAJ10242.1 - 1.6 9.0 5.3 4.7 7.5 0.5 2.6 3 0 0 3 3 2 0 Homeobox associated leucine zipper TarH PF02203.15 OAJ10242.1 - 1.7 8.6 10.5 1 9.3 8.7 1.5 1 1 1 2 2 2 0 Tar ligand binding domain homologue ADIP PF11559.8 OAJ10242.1 - 2.4 8.3 14.9 3.5 7.7 0.1 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 OAJ10242.1 - 3.5 8.1 14.4 2.4 8.6 7.7 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) rve PF00665.26 OAJ10251.1 - 5.6e-15 55.6 0.0 9.7e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ10253.1 - 4.1e-05 23.5 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10253.1 - 0.15 12.4 0.0 4.7 7.6 0.0 2.2 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF3224 PF11528.8 OAJ10253.1 - 0.23 11.3 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) RT_RNaseH_2 PF17919.1 OAJ10260.1 - 9.8e-30 102.5 0.0 2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10260.1 - 1.1e-25 89.9 0.0 3.2e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10260.1 - 2.5e-14 53.5 0.0 7.2e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10260.1 - 1.3e-09 38.0 0.1 2.4e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ10260.1 - 4.6e-05 23.1 0.3 0.0031 17.3 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain DUF2268 PF10026.9 OAJ10260.1 - 0.011 15.3 1.5 0.014 15.0 0.2 1.7 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Caskin-tail PF16632.5 OAJ10267.1 - 0.36 11.3 3.8 0.55 10.7 2.0 2.3 1 1 1 2 2 2 0 C-terminal region of Caskin Dicty_REP PF05086.12 OAJ10267.1 - 7.2 4.5 8.5 10 3.9 8.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ICMT PF04140.14 OAJ10269.1 - 1.8e-13 50.7 0.8 1.8e-13 50.7 0.8 2.1 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ10269.1 - 1.8e-08 34.7 2.1 1.1e-07 32.2 2.1 2.1 1 1 0 1 1 1 1 Phospholipid methyltransferase AP3D1 PF06375.11 OAJ10287.1 - 0.024 14.9 3.3 0.038 14.2 3.3 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SWIRM-assoc_2 PF16496.5 OAJ10287.1 - 0.1 11.5 7.0 0.15 10.9 7.0 1.3 1 1 0 1 1 1 0 SWIRM-associated domain at the N-terminal Peptidase_S8 PF00082.22 OAJ10295.1 - 6.3e-44 150.4 0.0 1.6e-43 149.1 0.0 1.6 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ10295.1 - 6.6e-12 46.1 1.7 6.6e-12 46.1 1.7 2.5 3 0 0 3 3 3 1 Fn3-like domain Inhibitor_I9 PF05922.16 OAJ10295.1 - 0.025 15.2 0.1 0.061 14.0 0.1 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 PA PF02225.22 OAJ10295.1 - 0.038 14.0 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 PA domain F-box-like PF12937.7 OAJ10312.1 - 0.035 14.0 1.2 9.8 6.2 0.1 3.0 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 OAJ10312.1 - 0.077 12.9 0.5 2 8.4 0.0 2.5 2 0 0 2 2 2 0 F-box domain Nop14 PF04147.12 OAJ10313.1 - 0.17 10.0 2.7 0.23 9.6 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family FMN_dh PF01070.18 OAJ10314.1 - 4e-118 394.4 0.0 4.9e-118 394.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAJ10314.1 - 2.6e-21 75.5 0.1 7.1e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAJ10314.1 - 1.8e-05 24.1 0.0 2.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ10314.1 - 0.0013 17.8 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Vps5 PF09325.10 OAJ10314.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Aldedh PF00171.22 OAJ10315.1 - 6.9e-116 387.5 0.8 8.5e-116 387.2 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5063 PF16702.5 OAJ10315.1 - 0.018 15.4 0.0 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) SEP PF08059.13 OAJ10330.1 - 1.4e-18 67.2 0.0 3e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OAJ10330.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAJ10330.1 - 1.1e-10 41.1 0.7 2.3e-10 40.1 0.7 1.5 1 0 0 1 1 1 1 UBA-like domain Pinin_SDK_N PF04697.13 OAJ10330.1 - 0.7 10.5 4.5 2.5 8.8 4.5 1.9 1 0 0 1 1 1 0 pinin/SDK conserved region Gpi16 PF04113.14 OAJ10331.1 - 7.9e-99 331.6 0.0 6.6e-49 166.8 0.0 3.8 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component Ubiq_cyt_C_chap PF03981.12 OAJ10332.1 - 2.1e-29 102.4 0.1 1.1e-26 93.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone SOG2 PF10428.9 OAJ10332.1 - 9.5 5.3 14.7 14 4.7 14.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Oxysterol_BP PF01237.18 OAJ10337.1 - 6.9e-65 219.3 0.0 1.3e-58 198.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein XPA_C PF05181.12 OAJ10338.1 - 3.2e-24 84.6 1.0 6.3e-24 83.7 1.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 OAJ10338.1 - 0.1 12.6 5.6 0.14 12.2 0.9 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 OAJ10338.1 - 0.74 9.5 2.7 0.59 9.8 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Prenyltransf PF01255.19 OAJ10339.1 - 1.5e-71 240.5 0.0 3.1e-71 239.5 0.0 1.4 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase XPA_C PF05181.12 OAJ10339.1 - 8.3e-24 83.3 0.8 1.7e-23 82.3 0.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus DEAD PF00270.29 OAJ10350.1 - 2e-18 66.8 0.0 7.9e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10350.1 - 0.0061 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop14 PF04147.12 OAJ10351.1 - 9.5e-269 894.3 5.4 1.6e-268 893.6 5.4 1.3 1 0 0 1 1 1 1 Nop14-like family ATP-synt_ab PF00006.25 OAJ10370.1 - 1.9e-67 227.1 0.0 2.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ10370.1 - 1.5e-13 51.1 0.3 2.5e-13 50.3 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OAJ10370.1 - 0.057 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DUF4604 PF15377.6 OAJ10371.1 - 4.2e-19 69.6 17.6 4.8e-19 69.4 17.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) U1snRNP70_N PF12220.8 OAJ10371.1 - 0.9 10.2 8.8 2.2 9.0 3.6 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MAJIN PF15077.6 OAJ10371.1 - 1.3 8.8 9.9 0.36 10.6 0.4 2.0 2 0 0 2 2 2 0 Membrane-anchored junction protein DUF572 PF04502.13 OAJ10371.1 - 1.3 8.6 11.8 1.6 8.2 11.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S49_N PF08496.10 OAJ10371.1 - 2.1 8.4 9.5 1.1 9.3 4.5 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-FCS PF06467.14 OAJ10372.1 - 0.17 11.9 3.7 0.33 10.9 3.7 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Retrotrans_gag PF03732.17 OAJ10379.1 - 0.002 18.4 1.3 0.029 14.7 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4349 PF14257.6 OAJ10379.1 - 0.004 16.6 0.8 0.0075 15.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DUF892 PF05974.12 OAJ10379.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) ABC_tran_CTD PF16326.5 OAJ10379.1 - 0.075 13.3 2.3 0.16 12.3 2.3 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain ArnB_C PF18677.1 OAJ10379.1 - 0.16 12.1 1.0 0.35 11.0 1.0 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Sec31 PF11549.8 OAJ10379.1 - 0.38 10.7 6.6 0.87 9.5 0.1 2.8 2 0 0 2 2 2 0 Protein transport protein SEC31 RVT_1 PF00078.27 OAJ10380.1 - 9.7e-23 80.8 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10380.1 - 1.4e-18 66.8 0.0 1.2e-12 47.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10380.1 - 2.2e-14 53.3 0.0 4.3e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10380.1 - 6.9e-14 52.0 0.0 1.2e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10380.1 - 8.6e-12 45.3 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10380.1 - 7.2e-05 23.4 0.0 0.00033 21.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10380.1 - 0.00089 19.8 0.0 0.0039 17.7 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RNA_pol_Rpb1_7 PF04990.12 OAJ10390.1 - 0.034 14.1 0.4 0.04 13.9 0.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 FAM76 PF16046.5 OAJ10390.1 - 0.14 11.5 2.5 0.14 11.5 2.5 1.0 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 OAJ10390.1 - 0.32 10.0 4.7 0.38 9.8 4.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 OAJ10395.1 - 0.0011 19.3 8.1 0.0015 18.9 7.1 1.8 1 1 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 OAJ10395.1 - 0.037 13.6 4.6 0.096 12.3 4.6 1.7 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator UPF0242 PF06785.11 OAJ10395.1 - 0.22 11.6 6.6 0.37 10.9 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4554 PF15091.6 OAJ10395.1 - 0.77 8.6 3.7 1.3 7.8 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) GAS PF13851.6 OAJ10395.1 - 1.6 8.0 11.9 2.7 7.3 11.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PikAIV_N PF18605.1 OAJ10395.1 - 3 7.5 15.6 0.24 11.0 3.7 3.7 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NinG PF05766.12 OAJ10395.1 - 5.8 6.8 9.4 32 4.4 5.4 2.4 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein CHAD PF05235.14 OAJ10403.1 - 0.067 13.2 13.1 0.016 15.2 5.4 2.1 2 0 0 2 2 2 0 CHAD domain LTXXQ PF07813.12 OAJ10403.1 - 4.3 8.1 11.4 0.9 10.3 2.6 3.1 3 1 0 3 3 3 0 LTXXQ motif family protein Pro-rich_19 PF15455.6 OAJ10404.1 - 0.042 13.0 1.0 0.048 12.8 1.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 CCDC85 PF10226.9 OAJ10404.1 - 0.097 12.3 0.7 0.17 11.5 0.6 1.6 1 1 0 1 1 1 0 CCDC85 family Tyrosinase PF00264.20 OAJ10420.1 - 5.4e-05 23.6 0.0 6.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase PH PF00169.29 OAJ10435.1 - 4.7e-10 39.9 0.1 8.9e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAJ10435.1 - 0.0072 16.7 0.3 0.018 15.4 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RA PF00788.23 OAJ10435.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF4746 PF15928.5 OAJ10436.1 - 0.071 12.5 0.7 0.13 11.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RT_RNaseH PF17917.1 OAJ10442.1 - 1e-28 99.6 0.0 2.5e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10442.1 - 2.3e-20 72.5 0.0 4.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10442.1 - 1.7e-17 63.7 0.3 3.1e-17 62.8 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10442.1 - 4.7e-17 61.8 0.1 1.1e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10442.1 - 5.6e-11 42.7 0.0 1.7e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 OAJ10442.1 - 6.4e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ10442.1 - 3.4e-06 27.5 0.0 7.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ10442.1 - 3.2e-05 24.0 0.0 8.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC PF00098.23 OAJ10442.1 - 4.8e-05 23.2 2.3 0.0001 22.2 2.3 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAJ10442.1 - 0.00011 22.7 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.6 OAJ10442.1 - 0.0061 16.4 1.6 0.013 15.4 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Chromo PF00385.24 OAJ10442.1 - 0.0072 16.2 0.2 0.022 14.6 0.2 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_6 PF15288.6 OAJ10442.1 - 0.016 15.0 0.8 0.016 15.0 0.8 2.2 2 0 0 2 2 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ10442.1 - 0.061 13.3 1.2 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle CLIP1_ZNF PF16641.5 OAJ10442.1 - 0.15 12.0 1.6 0.32 10.9 1.6 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle Herpes_DNAp_acc PF04929.12 OAJ10442.1 - 3.2 6.7 6.9 1.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Herpes DNA replication accessory factor RT_RNaseH PF17917.1 OAJ10448.1 - 1e-28 99.7 0.0 2.4e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10448.1 - 6.4e-20 71.1 0.0 1.3e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10448.1 - 7.2e-17 61.3 0.0 1.7e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ10448.1 - 2.4e-15 56.7 0.5 4.5e-15 55.8 0.5 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10448.1 - 1.9e-12 47.4 0.0 6.4e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10448.1 - 0.0047 17.1 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 OAJ10448.1 - 0.0062 16.4 0.2 0.019 14.8 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cadherin_4 PF17803.1 OAJ10449.1 - 0.12 13.0 3.7 0.28 11.9 3.7 1.6 1 0 0 1 1 1 0 Bacterial cadherin-like domain Asp_protease_2 PF13650.6 OAJ10450.1 - 4.6e-07 30.4 0.0 1.3e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10450.1 - 5.3e-07 30.1 0.0 3.4e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OAJ10450.1 - 2.9e-06 27.1 0.0 5.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ10450.1 - 5.1e-05 23.1 2.6 0.0001 22.2 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ10450.1 - 0.0024 18.1 0.0 0.0059 16.9 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 OAJ10450.1 - 0.024 14.4 2.6 0.05 13.4 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ10450.1 - 0.13 12.3 0.3 0.34 10.9 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Ion_trans PF00520.31 OAJ10458.1 - 4.9e-11 42.3 8.0 5.5e-10 38.9 8.0 2.1 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAJ10458.1 - 5.8e-06 25.2 15.5 2.7e-05 23.0 13.2 2.6 2 1 0 2 2 2 1 Polycystin cation channel Toxin_29 PF08116.11 OAJ10459.1 - 0.00041 20.3 1.6 0.00041 20.3 1.6 11.1 9 3 3 12 12 12 1 PhTx neurotoxin family Toxin_21 PF08091.11 OAJ10459.1 - 0.12 12.4 0.3 0.12 12.4 0.3 9.6 6 3 3 9 9 9 0 Spider insecticidal peptide EB PF01683.18 OAJ10459.1 - 7.3 7.0 127.8 1.9 8.8 5.8 11.4 2 2 8 10 10 10 0 EB module Septin PF00735.18 OAJ10460.1 - 1.2e-58 198.6 0.1 1.4e-58 198.4 0.1 1.0 1 0 0 1 1 1 1 Septin SAM_decarbox PF01536.16 OAJ10464.1 - 3.1e-119 398.1 0.0 7.4e-119 396.9 0.0 1.6 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase CagX PF03524.15 OAJ10465.1 - 2.2 7.9 6.0 5 6.8 6.0 1.5 1 0 0 1 1 1 0 Conjugal transfer protein IFT20 PF14931.6 OAJ10465.1 - 4.2 7.6 23.6 0.29 11.3 6.9 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 LIP PF03583.14 OAJ10466.1 - 4.4e-60 203.4 0.1 5.7e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ10466.1 - 0.22 10.9 0.0 12 5.2 0.0 2.3 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF829 PF05705.14 OAJ10466.1 - 0.23 11.3 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) XPA_C PF05181.12 OAJ10480.1 - 1.9e-24 85.4 0.4 2.7e-24 84.9 0.4 1.3 1 0 0 1 1 1 1 XPA protein C-terminus Mitofilin PF09731.9 OAJ10481.1 - 1.1e-75 255.7 42.5 8.2e-44 150.5 35.1 3.0 2 1 0 2 2 2 2 Mitochondrial inner membrane protein Herpes_IR6 PF06307.12 OAJ10481.1 - 0.0015 18.2 0.2 0.0033 17.0 0.2 1.5 1 0 0 1 1 1 1 Herpesvirus IR6 protein DUF842 PF05811.13 OAJ10481.1 - 0.14 11.8 11.5 2.5 7.8 3.7 3.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) EAP30 PF04157.16 OAJ10482.1 - 7e-58 195.7 0.0 8.3e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Glyco_hydro_79C PF16862.5 OAJ10492.1 - 4.7e-12 46.7 0.1 1.1e-11 45.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RVT_1 PF00078.27 OAJ10501.1 - 1.8e-09 37.5 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AMP-binding PF00501.28 OAJ10503.1 - 3.1e-63 213.9 0.0 5e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ10503.1 - 6.6e-20 71.9 0.5 1.6e-19 70.6 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Dioxygenase_C PF00775.21 OAJ10512.1 - 1.6e-06 27.7 0.2 7.3e-06 25.5 0.2 1.9 1 1 0 1 1 1 1 Dioxygenase Methyltransf_16 PF10294.9 OAJ10513.1 - 2.3e-41 141.4 0.0 3.9e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAJ10513.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ10513.1 - 0.18 12.5 0.1 0.41 11.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Chs7 PF12271.8 OAJ10514.1 - 2e-114 381.8 17.0 2.3e-114 381.6 17.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Fungal_trans PF04082.18 OAJ10525.1 - 1.1e-26 93.5 0.0 2.2e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAJ10525.1 - 6.2e-08 32.7 11.8 0.00028 21.2 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ10525.1 - 0.00067 20.3 10.7 0.0057 17.4 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ10525.1 - 0.033 14.8 5.1 1.4 9.6 0.4 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF1610 PF07754.11 OAJ10525.1 - 0.05 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-C2H2_8 PF15909.5 OAJ10525.1 - 0.087 13.1 0.5 0.24 11.7 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 OAJ10525.1 - 0.18 11.9 1.5 0.42 10.8 1.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 OAJ10525.1 - 6.3 7.4 8.8 0.67 10.5 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain WES_acyltransf PF03007.16 OAJ10526.1 - 5.6e-15 55.8 0.0 1.3e-14 54.7 0.0 1.7 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ10526.1 - 8.6e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Glyco_H_20C_C PF18088.1 OAJ10531.1 - 6.5e-35 120.8 0.0 5.3e-34 117.8 0.0 2.4 3 0 0 3 3 3 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 OAJ10531.1 - 2e-07 30.7 0.0 1.5e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Mersacidin PF16934.5 OAJ10531.1 - 0.095 12.5 0.2 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) MMS19_N PF14500.6 OAJ10532.1 - 6.4e-64 216.0 0.6 9.1e-54 182.8 0.0 3.2 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OAJ10532.1 - 8e-46 157.0 4.0 2.7e-45 155.2 0.0 3.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal TAF6_C PF07571.13 OAJ10532.1 - 0.0047 17.2 0.1 0.092 13.1 0.1 3.1 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain DUF3453 PF11935.8 OAJ10532.1 - 0.044 13.4 0.1 0.25 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) HEAT PF02985.22 OAJ10532.1 - 0.43 11.0 9.4 1.5 9.3 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat ATG16 PF08614.11 OAJ10539.1 - 0.00012 22.4 8.8 0.00018 21.8 8.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ExsD PF16806.5 OAJ10539.1 - 0.0061 16.5 1.0 0.0074 16.2 1.0 1.1 1 0 0 1 1 1 1 Antiactivator protein ExsD Filament PF00038.21 OAJ10539.1 - 0.012 15.2 6.3 0.015 14.9 6.3 1.1 1 0 0 1 1 1 0 Intermediate filament protein Sec2p PF06428.11 OAJ10539.1 - 0.021 14.8 6.9 0.34 10.9 1.1 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2959 PF11172.8 OAJ10539.1 - 0.025 14.7 4.2 0.03 14.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) FapA PF03961.13 OAJ10539.1 - 0.032 12.8 1.9 0.038 12.6 1.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FAM76 PF16046.5 OAJ10539.1 - 0.062 12.7 2.4 0.075 12.4 2.4 1.0 1 0 0 1 1 1 0 FAM76 protein EMP24_GP25L PF01105.24 OAJ10539.1 - 0.089 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3584 PF12128.8 OAJ10539.1 - 0.11 10.0 8.8 0.12 9.8 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DMPK_coil PF08826.10 OAJ10539.1 - 0.13 12.4 10.4 0.32 11.1 2.6 2.5 1 1 1 2 2 2 0 DMPK coiled coil domain like Golgin_A5 PF09787.9 OAJ10539.1 - 0.25 10.8 6.4 0.31 10.5 6.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 OAJ10539.1 - 0.52 9.5 2.8 0.65 9.2 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 OAJ10539.1 - 1 9.5 13.1 2.4 8.2 12.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 OAJ10539.1 - 3.1 7.1 8.6 3.9 6.8 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 OAJ10540.1 - 3.3e-06 27.5 12.1 4.4e-06 27.1 12.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ExsD PF16806.5 OAJ10540.1 - 0.0012 18.9 4.9 0.0014 18.6 4.9 1.1 1 0 0 1 1 1 1 Antiactivator protein ExsD AAA_11 PF13086.6 OAJ10540.1 - 0.0052 16.6 5.3 0.0065 16.3 5.3 1.0 1 0 0 1 1 1 1 AAA domain DUF745 PF05335.13 OAJ10540.1 - 0.0081 15.9 13.1 0.011 15.5 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Helo_like_N PF17111.5 OAJ10540.1 - 0.012 14.9 1.9 0.016 14.6 1.9 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins FAM76 PF16046.5 OAJ10540.1 - 0.014 14.7 4.8 0.017 14.5 4.8 1.0 1 0 0 1 1 1 0 FAM76 protein EMP24_GP25L PF01105.24 OAJ10540.1 - 0.016 15.2 2.5 0.02 14.8 2.5 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD FapA PF03961.13 OAJ10540.1 - 0.022 13.4 5.3 0.027 13.1 5.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 OAJ10540.1 - 0.057 13.6 2.3 0.078 13.2 2.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.9 OAJ10540.1 - 0.064 13.5 15.8 0.1 12.8 15.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DMPK_coil PF08826.10 OAJ10540.1 - 0.072 13.2 13.1 0.17 12.0 6.0 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF3584 PF12128.8 OAJ10540.1 - 0.13 9.7 14.0 0.15 9.6 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rx_N PF18052.1 OAJ10540.1 - 0.13 12.5 3.9 0.25 11.6 3.9 1.5 1 0 0 1 1 1 0 Rx N-terminal domain Fmp27_WPPW PF10359.9 OAJ10540.1 - 0.16 10.8 4.9 0.17 10.7 4.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.6 OAJ10540.1 - 0.28 11.2 10.9 0.22 11.5 9.5 1.5 1 1 0 1 1 1 0 FlxA-like protein FlaC_arch PF05377.11 OAJ10540.1 - 0.6 10.5 2.9 1.2 9.6 2.8 1.7 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 OAJ10540.1 - 0.78 8.9 4.9 1 8.6 4.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein Tho2 PF11262.8 OAJ10540.1 - 1.4 8.0 5.5 1.7 7.8 5.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Fzo_mitofusin PF04799.13 OAJ10540.1 - 5.7 6.5 9.4 7.1 6.2 2.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region TPR_21 PF09976.9 OAJ10544.1 - 0.044 13.5 4.5 0.097 12.4 4.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain CDT1_C PF16679.5 OAJ10544.1 - 0.069 13.6 2.5 0.18 12.2 2.5 1.8 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain HA2 PF04408.23 OAJ10545.1 - 2.7e-14 53.3 0.0 5.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ10545.1 - 2.9e-13 50.1 0.0 5.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ10545.1 - 2e-05 24.5 0.2 3.7e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 OAJ10545.1 - 0.00015 22.4 0.2 0.00015 22.4 0.2 4.3 5 0 0 5 5 5 1 Double-stranded RNA binding motif AAA_19 PF13245.6 OAJ10545.1 - 0.00081 19.7 0.1 0.00081 19.7 0.1 1.9 3 0 0 3 3 3 1 AAA domain F-box-like PF12937.7 OAJ10555.1 - 2.9e-08 33.5 0.2 7.1e-08 32.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ10555.1 - 2.1e-05 24.2 0.1 5.9e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain Fringe PF02434.16 OAJ10556.1 - 0.75 9.2 2.7 13 5.1 2.7 2.1 1 1 0 1 1 1 0 Fringe-like RT_RNaseH_2 PF17919.1 OAJ10566.1 - 1.3e-16 60.4 0.0 3.9e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10566.1 - 1.9e-13 50.3 0.2 5.3e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 OAJ10566.1 - 2.2e-05 24.6 0.0 9.8e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ10566.1 - 0.0012 19.0 0.0 0.0065 16.7 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Oxygenase-NA PF09859.9 OAJ10566.1 - 0.021 14.3 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA RVT_1 PF00078.27 OAJ10567.1 - 5.7e-07 29.3 0.0 8.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ10567.1 - 0.00011 22.8 0.1 0.00039 21.0 0.1 2.0 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10567.1 - 0.0085 16.6 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ10567.1 - 0.096 13.0 0.0 0.84 10.0 0.0 2.3 1 1 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OAJ10568.1 - 0.00089 19.5 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Mucin PF01456.17 OAJ10568.1 - 0.074 13.1 7.9 0.028 14.4 4.0 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RPA_interact_C PF14768.6 OAJ10576.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.7 1 1 0 1 1 1 0 Replication protein A interacting C-terminal peroxidase PF00141.23 OAJ10578.1 - 4.5e-48 163.9 0.0 8.1e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Mito_carr PF00153.27 OAJ10579.1 - 2.5e-24 85.0 5.4 2.6e-20 72.1 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein SPX PF03105.19 OAJ10579.1 - 0.48 10.3 8.5 0.86 9.5 8.5 1.4 1 0 0 1 1 1 0 SPX domain E1-E2_ATPase PF00122.20 OAJ10588.1 - 1.9e-49 167.7 0.0 3.6e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OAJ10588.1 - 1.6e-10 40.5 0.0 5.1e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ10588.1 - 0.0035 17.4 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) mRNA_cap_enzyme PF01331.19 OAJ10589.1 - 3e-50 170.8 0.1 4e-50 170.4 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAJ10589.1 - 7.9e-28 97.3 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAJ10589.1 - 3.2e-08 33.5 0.0 4.9e-05 23.1 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain PGM_PMM_I PF02878.16 OAJ10590.1 - 9.9e-38 129.0 0.0 1.5e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAJ10590.1 - 1.3e-27 96.2 0.0 3.3e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ10590.1 - 2.1e-13 50.8 0.0 4.2e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAJ10590.1 - 6.1e-06 26.3 0.0 2.1e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Dimer_Tnp_hAT PF05699.14 OAJ10598.1 - 7.1e-11 41.7 0.0 1.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RCC1 PF00415.18 OAJ10599.1 - 3.8e-18 65.9 0.1 4.4e-05 24.0 0.0 4.5 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ10599.1 - 7.2e-15 54.3 5.2 6.8e-07 28.9 0.2 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF4767 PF15983.5 OAJ10599.1 - 0.21 11.9 1.9 0.42 10.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) DEAD PF00270.29 OAJ10607.1 - 1.5e-10 41.1 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ10607.1 - 5.1e-09 36.5 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ10607.1 - 0.01 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GARP PF16731.5 OAJ10607.1 - 0.14 11.8 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma zf-C2H2 PF00096.26 OAJ10607.1 - 0.42 11.2 13.5 1.6 9.3 3.9 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DnaJ-X PF14308.6 OAJ10619.1 - 1.2e-62 211.1 0.0 1.2e-62 211.1 0.0 2.4 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ10619.1 - 3.4e-17 62.3 0.2 1.4e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Proteasome PF00227.26 OAJ10620.1 - 4.5e-51 173.0 0.9 6.6e-51 172.5 0.3 1.5 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.8 OAJ10620.1 - 1.3e-05 24.5 0.1 1.3e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal CclA_1 PF16942.5 OAJ10621.1 - 0.19 12.0 3.6 0.21 11.9 3.6 1.1 1 0 0 1 1 1 0 Putative cyclic bacteriocin IL32 PF15225.6 OAJ10621.1 - 0.84 10.0 3.7 0.94 9.9 0.8 1.9 1 1 1 2 2 2 0 Interleukin 32 MRP-L47 PF06984.13 OAJ10622.1 - 1.1e-14 54.3 0.7 2e-14 53.5 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 OAJ10622.1 - 0.0018 18.2 4.2 0.011 15.7 4.2 2.1 1 1 0 1 1 1 1 Ribosomal L29 protein DUF733 PF05306.11 OAJ10622.1 - 0.052 13.9 0.2 0.087 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF733) Tail_VII PF17091.5 OAJ10623.1 - 1.5 8.8 4.6 2.7 7.9 4.6 1.4 1 0 0 1 1 1 0 Inovirus G7P protein MULE PF10551.9 OAJ10632.1 - 3.6e-20 72.2 0.1 1.7e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ10632.1 - 3.5e-09 36.0 0.0 5.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 OAJ10632.1 - 2.7e-08 33.7 0.7 6.8e-07 29.2 0.5 2.6 2 0 0 2 2 2 1 MuDR family transposase CLIP1_ZNF PF16641.5 OAJ10632.1 - 0.066 13.1 1.8 1.2 9.1 1.1 2.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC PF00098.23 OAJ10632.1 - 0.82 9.9 4.7 0.36 11.0 1.5 2.1 2 0 0 2 2 2 0 Zinc knuckle F420_oxidored PF03807.17 OAJ10641.1 - 0.067 13.8 0.1 0.15 12.7 0.0 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DDE_1 PF03184.19 OAJ10643.1 - 1.5e-38 132.2 0.1 2.5e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ10643.1 - 4.5e-12 45.8 0.0 1.1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Amidohydro_1 PF01979.20 OAJ10649.1 - 3.2e-66 224.0 0.1 4.9e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OAJ10649.1 - 6.6e-58 194.3 0.5 2.1e-57 192.7 0.5 1.9 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OAJ10649.1 - 1.4e-42 144.0 0.6 2.9e-42 143.0 0.6 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 OAJ10649.1 - 2.3e-35 120.5 0.0 6.9e-35 119.0 0.0 1.8 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 OAJ10649.1 - 2.2e-08 34.0 0.2 1.1e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family Ribosomal_S11 PF00411.19 OAJ10650.1 - 4.4e-10 39.9 0.2 5.5e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S11 SPX PF03105.19 OAJ10650.1 - 0.07 13.0 5.0 0.08 12.8 5.0 1.3 1 0 0 1 1 1 0 SPX domain RNase_PH PF01138.21 OAJ10651.1 - 2.6e-16 60.3 0.0 4.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF3405 PF11885.8 OAJ10652.1 - 1.6e-80 271.2 7.8 6.4e-51 173.5 0.3 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3405) Pex14_N PF04695.13 OAJ10652.1 - 0.89 10.2 0.0 0.89 10.2 0.0 3.2 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TIM21 PF08294.11 OAJ10656.1 - 1.4e-13 51.0 0.1 5.8e-12 45.7 0.0 2.7 2 1 0 2 2 2 1 TIM21 APH PF01636.23 OAJ10657.1 - 1.3e-19 71.1 0.4 1.3e-19 71.1 0.4 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ10657.1 - 0.0098 15.5 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family ADH_zinc_N PF00107.26 OAJ10658.1 - 6e-28 97.4 0.1 9.7e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ10658.1 - 1.5e-13 51.9 0.0 2.7e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ10658.1 - 2.3e-07 30.7 0.0 1.6e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain SIR2 PF02146.17 OAJ10659.1 - 5e-30 104.7 0.0 1.9e-18 67.0 0.0 2.1 2 0 0 2 2 2 2 Sir2 family Hva1_TUDOR PF11160.8 OAJ10660.1 - 3.1e-18 65.7 1.7 3.7e-18 65.4 1.7 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain F-box-like PF12937.7 OAJ10666.1 - 2.6e-05 24.0 0.2 5.4e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ10666.1 - 0.011 15.6 0.5 0.03 14.2 0.5 1.7 1 0 0 1 1 1 0 F-box domain zf-RING_UBOX PF13445.6 OAJ10667.1 - 3.8e-06 26.8 0.2 3.8e-06 26.8 0.2 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ10667.1 - 1.2e-05 25.5 1.1 5.4e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAJ10667.1 - 7.9e-05 22.5 0.7 0.00031 20.6 0.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAJ10667.1 - 0.0004 20.1 1.3 0.00082 19.1 1.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAJ10667.1 - 0.016 15.0 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ10667.1 - 0.046 13.6 2.9 0.051 13.4 0.2 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OAJ10668.1 - 2.7e-34 116.6 28.7 2.4e-06 28.1 0.4 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ10668.1 - 4.2e-13 49.4 1.0 0.0042 17.3 0.0 6.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OAJ10668.1 - 1.1e-09 38.0 0.1 2.2e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OAJ10668.1 - 6.2e-08 31.7 8.0 0.35 9.5 0.0 5.7 4 1 2 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 OAJ10668.1 - 5e-07 29.3 0.1 0.00034 20.0 0.0 3.7 2 1 1 4 4 4 1 WD40-like domain Kelch_6 PF13964.6 OAJ10668.1 - 0.0001 22.5 1.5 0.87 10.0 0.1 5.1 5 0 0 5 5 5 1 Kelch motif F-box PF00646.33 OAJ10668.1 - 0.00039 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 OAJ10668.1 - 0.00065 19.4 6.7 0.21 11.1 0.1 4.0 3 1 1 4 4 4 2 PQQ-like domain PQQ_3 PF13570.6 OAJ10668.1 - 0.0024 18.3 9.0 5.7 7.6 0.0 6.4 5 1 2 7 7 7 2 PQQ-like domain DUF5046 PF16465.5 OAJ10668.1 - 0.0091 15.5 0.1 0.46 9.9 0.0 2.8 1 1 0 2 2 2 1 Domain of unknown function (DUF5046) PQQ PF01011.21 OAJ10668.1 - 0.67 10.0 5.1 93 3.2 0.0 5.4 7 0 0 7 7 7 0 PQQ enzyme repeat Det1 PF09737.9 OAJ10679.1 - 0.057 12.5 0.3 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Chorion_2 PF03964.15 OAJ10679.1 - 0.11 13.3 0.5 0.17 12.8 0.5 1.3 1 0 0 1 1 1 0 Chorion family 2 Dimer_Tnp_hAT PF05699.14 OAJ10680.1 - 5.1e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 3-alpha PF03475.14 OAJ10680.1 - 0.0095 15.8 0.1 0.024 14.5 0.1 1.7 1 0 0 1 1 1 1 3-alpha domain TcpS PF17456.2 OAJ10689.1 - 0.0078 16.3 0.0 0.009 16.1 0.0 1.0 1 0 0 1 1 1 1 Toxin-coregulated pilus protein S fn3_6 PF17766.1 OAJ10689.1 - 0.028 14.6 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Fibronectin type-III domain PNTB_4TM PF12769.7 OAJ10700.1 - 0.041 14.4 0.1 0.041 14.4 0.1 1.8 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch HIG_1_N PF04588.13 OAJ10700.1 - 0.34 11.2 0.1 0.34 11.2 0.1 2.1 2 1 0 2 2 2 0 Hypoxia induced protein conserved region Pkinase PF00069.25 OAJ10701.1 - 0.00082 18.8 0.0 0.00098 18.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10701.1 - 0.16 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase HTH_Tnp_1 PF01527.20 OAJ10702.1 - 0.015 15.6 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 Transposase Pkinase PF00069.25 OAJ10703.1 - 1.3e-69 234.5 0.0 1.6e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10703.1 - 4.3e-49 167.1 0.0 6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ10703.1 - 4.1e-06 25.8 0.3 7.7e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAJ10703.1 - 0.0014 18.0 0.0 0.005 16.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like TPR_19 PF14559.6 OAJ10710.1 - 0.012 16.1 0.3 0.54 10.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Esterase PF00756.20 OAJ10717.1 - 0.00048 19.8 0.1 0.00089 19.0 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Esterase PF00756.20 OAJ10718.1 - 0.0007 19.3 0.0 0.00088 19.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OAJ10718.1 - 0.025 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold MOSC_N PF03476.16 OAJ10719.1 - 1.5e-21 76.5 0.0 2.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ10719.1 - 1e-05 25.6 0.2 5.2e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 MOSC domain 7tm_7 PF08395.12 OAJ10720.1 - 0.047 12.9 0.5 0.076 12.2 0.5 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor CPP1-like PF11833.8 OAJ10720.1 - 0.27 10.9 0.7 0.57 9.8 0.7 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like OrsD PF12013.8 OAJ10725.1 - 0.015 15.7 0.1 0.037 14.5 0.1 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4545 PF15078.6 OAJ10725.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) Activator_LAG-3 PF11498.8 OAJ10730.1 - 0.0014 17.7 8.3 0.0014 17.7 8.3 3.4 4 0 0 4 4 4 1 Transcriptional activator LAG-3 Cauli_VI PF01693.16 OAJ10745.1 - 3.9e-05 23.9 0.0 7.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin She9_MDM33 PF05546.11 OAJ10746.1 - 1.2e-61 208.1 7.5 1.2e-61 208.1 7.5 1.7 1 1 0 1 1 1 1 She9 / Mdm33 family DUF3496 PF12001.8 OAJ10746.1 - 0.0051 17.2 4.5 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3496) DUF2207 PF09972.9 OAJ10746.1 - 0.026 13.3 0.0 0.037 12.8 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2730 PF10805.8 OAJ10746.1 - 0.12 12.5 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PIN_12 PF16289.5 OAJ10746.1 - 0.91 10.0 4.7 0.71 10.3 1.3 2.2 1 1 1 2 2 2 0 PIN domain AD PF09793.9 OAJ10746.1 - 2.5 8.3 6.6 9.3 6.5 0.7 3.0 1 1 0 2 2 2 0 Anticodon-binding domain V-ATPase_G_2 PF16999.5 OAJ10746.1 - 9.1 6.8 11.9 2.7 8.5 1.7 3.0 3 1 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit GDC-P PF02347.16 OAJ10748.1 - 8.8e-184 611.3 0.0 3.7e-173 576.3 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAJ10748.1 - 0.0099 15.2 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Fungal_trans PF04082.18 OAJ10760.1 - 4.3e-20 71.9 0.0 1.2e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ10760.1 - 5e-10 39.3 10.5 9.1e-10 38.5 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-3_zeta PF05091.12 OAJ10766.1 - 8.5e-182 605.7 0.0 3.4e-181 603.8 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BCAS2 PF05700.11 OAJ10767.1 - 3.6e-43 147.7 8.0 4.1e-43 147.5 8.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ZapB PF06005.12 OAJ10767.1 - 0.15 12.5 9.4 1.8 9.1 0.7 3.9 3 1 0 4 4 4 0 Cell division protein ZapB Cep57_MT_bd PF06657.13 OAJ10767.1 - 0.29 11.6 4.7 0.55 10.7 0.1 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Enkurin PF13864.6 OAJ10767.1 - 1.3 9.5 4.8 6.2 7.3 4.8 2.4 1 1 0 1 1 1 0 Calmodulin-binding DUF2373 PF10180.9 OAJ10775.1 - 5.8e-14 51.7 0.0 8.7e-10 38.3 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Macoilin PF09726.9 OAJ10775.1 - 4.5 5.7 17.4 7 5.1 17.4 1.3 1 0 0 1 1 1 0 Macoilin family Cwf_Cwc_15 PF04889.12 OAJ10775.1 - 6.3 6.4 28.6 0.019 14.7 16.2 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Pro_isomerase PF00160.21 OAJ10776.1 - 1.2e-13 51.6 0.1 2.7e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 OAJ10776.1 - 0.006 16.0 0.0 0.019 14.4 0.0 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 OAJ10776.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DarA_N PF18788.1 OAJ10786.1 - 0.034 14.2 1.0 0.61 10.2 0.1 2.8 3 0 0 3 3 3 0 Defence against restriction A N-terminal Arena_ncap_C PF17290.2 OAJ10787.1 - 0.068 12.5 1.5 0.11 11.9 1.5 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Pkinase PF00069.25 OAJ10794.1 - 3.8e-20 72.4 0.0 5.4e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10794.1 - 1.6e-11 44.0 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10794.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF1764 PF08576.10 OAJ10800.1 - 3.7e-21 75.9 23.8 2.4e-17 63.6 15.5 2.6 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF4775 PF16001.5 OAJ10800.1 - 0.011 15.1 19.3 0.014 14.9 19.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Dicty_REP PF05086.12 OAJ10800.1 - 1.6 6.6 11.7 2 6.3 11.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4551 PF15087.6 OAJ10800.1 - 1.8 7.3 12.1 2 7.2 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lin-8 PF03353.15 OAJ10800.1 - 2.5 7.6 10.7 3.3 7.2 10.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 OAJ10800.1 - 2.8 7.7 14.2 3.5 7.4 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 OAJ10800.1 - 3.5 6.3 10.0 3.9 6.1 10.0 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 OAJ10800.1 - 4.6 5.9 11.8 6 5.5 11.8 1.2 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 OAJ10800.1 - 6.2 5.9 15.6 7.6 5.6 15.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 OAJ10800.1 - 7.1 5.1 13.4 8 4.9 13.4 1.0 1 0 0 1 1 1 0 Macoilin family Cytochrom_C PF00034.21 OAJ10801.1 - 3.2e-08 34.6 0.0 3.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAJ10801.1 - 3.8e-07 30.3 1.2 3.8e-06 27.1 1.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAJ10801.1 - 0.0038 16.9 1.1 0.061 13.0 1.1 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.14 OAJ10801.1 - 0.097 13.3 0.0 0.1 13.2 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase EOS1 PF12326.8 OAJ10802.1 - 5.4e-45 153.4 4.0 3.3e-44 150.9 0.0 3.5 2 2 0 2 2 2 1 N-glycosylation protein eRF1_2 PF03464.15 OAJ10803.1 - 1.5e-43 148.3 0.0 2.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAJ10803.1 - 9.9e-37 125.9 0.0 2e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAJ10803.1 - 4.3e-19 68.8 0.0 7.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OAJ10803.1 - 1.4e-10 41.6 0.0 2.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OAJ10803.1 - 4.6e-09 36.7 0.0 7.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3440 PF11922.8 OAJ10803.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) MutS_V PF00488.21 OAJ10809.1 - 5e-44 150.6 0.0 1.2e-43 149.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ10809.1 - 1.5e-16 61.2 4.3 4.4e-16 59.7 0.3 2.9 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 OAJ10809.1 - 2e-06 28.0 0.0 5.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 OAJ10809.1 - 0.00094 19.5 4.9 0.41 10.9 0.5 4.1 3 1 0 3 3 3 1 MutS domain II AAA_22 PF13401.6 OAJ10809.1 - 0.11 12.8 0.0 0.45 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain PIG-P PF08510.12 OAJ10810.1 - 1.6e-24 86.2 0.5 1.9e-24 85.9 0.5 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 OAJ10810.1 - 0.016 15.5 1.8 0.027 14.8 1.8 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) RabGAP-TBC PF00566.18 OAJ10811.1 - 2e-30 106.1 8.6 1.1e-29 103.7 0.4 3.5 4 0 0 4 4 4 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAJ10811.1 - 0.0068 15.9 0.0 0.16 11.4 0.0 2.9 2 1 0 2 2 2 1 Rab-binding domain (RBD) Nucleo_P87 PF07267.11 OAJ10811.1 - 2.9 6.7 8.4 5.9 5.6 8.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3402 PF11882.8 OAJ10811.1 - 3.1 6.8 7.0 5.5 6.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Cep3 PF16846.5 OAJ10815.1 - 0.1 11.1 2.2 0.16 10.5 2.2 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B Asp-B-Hydro_N PF05279.11 OAJ10815.1 - 0.24 11.5 31.1 0.042 13.9 22.7 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Exonuc_VII_L PF02601.15 OAJ10815.1 - 3.8 7.0 17.0 7.3 6.1 17.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran PF00005.27 OAJ10830.1 - 0.0045 17.5 0.0 0.0069 16.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ10830.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DDE_3 PF13358.6 OAJ10831.1 - 2.7e-29 101.8 0.0 3.9e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ10831.1 - 9.5e-10 38.0 2.1 1.2e-08 34.5 0.2 2.9 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ10831.1 - 1.7e-06 28.5 0.1 0.00012 22.6 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ10831.1 - 2.8e-06 26.6 0.1 0.0064 15.5 0.0 2.2 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 OAJ10831.1 - 0.0022 18.2 0.4 0.0063 16.7 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 OAJ10831.1 - 0.098 12.5 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain MHC2-interact PF09307.10 OAJ10848.1 - 0.089 12.8 1.0 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting Coronavirus_5 PF05528.11 OAJ10855.1 - 0.29 11.1 1.4 47 4.1 0.1 2.9 2 1 1 3 3 3 0 Coronavirus gene 5 protein V_cholerae_RfbT PF05575.11 OAJ10856.1 - 0.03 13.6 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein Methyltransf_24 PF13578.6 OAJ10856.1 - 0.11 13.5 0.0 0.17 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Plus-3 PF03126.18 OAJ10864.1 - 4.8e-09 36.7 0.0 1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-CCHC_2 PF13696.6 OAJ10873.1 - 0.074 12.9 0.6 0.12 12.2 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 OAJ10875.1 - 1e-26 93.9 0.0 1.7e-26 93.2 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10875.1 - 1.9e-14 53.6 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ10875.1 - 0.00031 19.7 0.0 0.00039 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ10875.1 - 0.0026 17.1 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ10875.1 - 0.026 14.5 1.1 0.026 14.5 1.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family UreE_N PF02814.15 OAJ10875.1 - 0.27 10.9 1.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Dimer_Tnp_hAT PF05699.14 OAJ10882.1 - 2.6e-11 43.1 0.5 6.9e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TLD PF07534.16 OAJ10888.1 - 2.1e-24 86.3 0.0 4.7e-21 75.5 0.0 3.3 2 1 0 2 2 2 2 TLD UQ_con PF00179.26 OAJ10889.1 - 2.3e-20 72.7 0.0 4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SDA1 PF05285.12 OAJ10889.1 - 0.044 13.2 16.5 0.35 10.3 16.8 2.0 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 OAJ10889.1 - 0.31 9.3 10.3 0.47 8.7 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 OAJ10889.1 - 2 7.4 21.1 5.5 6.0 21.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 OAJ10889.1 - 2.6 6.2 15.9 4 5.5 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 OAJ10889.1 - 5.9 6.9 11.6 0.91 9.6 7.1 1.9 2 0 0 2 2 2 0 YL1 nuclear protein ADH_N PF08240.12 OAJ10898.1 - 0.05 13.5 1.3 0.079 12.8 1.3 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF4763 PF15960.5 OAJ10898.1 - 0.14 11.5 6.4 0.23 10.8 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Zn_clus PF00172.18 OAJ10898.1 - 0.27 11.4 8.7 0.42 10.8 8.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Rho_GDI PF02115.17 OAJ10903.1 - 2.8e-55 187.1 0.0 3.4e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Carn_acyltransf PF00755.20 OAJ10904.1 - 1.5e-196 654.6 0.0 1.7e-196 654.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Foie-gras_1 PF11817.8 OAJ10906.1 - 1.3e-09 38.0 0.0 2e-06 27.6 0.0 3.3 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.12 OAJ10906.1 - 6.7e-09 35.1 0.0 6.6e-05 21.9 0.1 2.4 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi FA_desaturase PF00487.24 OAJ10907.1 - 0.0091 15.9 1.6 2.9 7.6 1.0 2.2 2 0 0 2 2 2 2 Fatty acid desaturase DUF3099 PF11298.8 OAJ10907.1 - 0.0098 16.0 0.6 0.051 13.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3099) DUF1993 PF09351.10 OAJ10913.1 - 0.0052 16.9 1.8 0.011 15.8 1.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1993) Fib_alpha PF08702.10 OAJ10913.1 - 0.01 16.0 0.6 0.015 15.5 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Alpha-2-MRAP_C PF06401.11 OAJ10913.1 - 0.013 15.5 0.4 0.017 15.1 0.4 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Sugarporin_N PF11471.8 OAJ10913.1 - 0.014 15.3 3.0 0.023 14.7 0.0 2.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension PsbQ PF05757.11 OAJ10913.1 - 0.016 15.0 1.9 0.12 12.0 1.9 2.0 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Tup_N PF08581.10 OAJ10913.1 - 0.019 15.3 0.9 0.033 14.5 0.6 1.6 1 1 0 1 1 1 0 Tup N-terminal Exonuc_VII_L PF02601.15 OAJ10913.1 - 0.022 14.3 1.4 0.026 14.1 1.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 OAJ10913.1 - 0.026 14.8 1.7 0.065 13.5 1.5 1.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2968 PF11180.8 OAJ10913.1 - 0.038 13.6 3.8 0.063 12.9 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4472 PF14739.6 OAJ10913.1 - 0.04 14.7 1.8 0.07 13.9 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Cep57_MT_bd PF06657.13 OAJ10913.1 - 0.04 14.4 6.0 0.72 10.3 4.9 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 EzrA PF06160.12 OAJ10913.1 - 0.047 11.9 0.5 0.058 11.6 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CLZ PF16526.5 OAJ10913.1 - 0.051 13.9 4.4 0.091 13.1 1.9 2.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MetRS-N PF09635.10 OAJ10913.1 - 0.063 13.8 0.4 0.098 13.2 0.4 1.3 1 0 0 1 1 1 0 MetRS-N binding domain Tropomyosin PF00261.20 OAJ10913.1 - 0.097 12.0 5.2 1.8 7.9 3.6 2.5 2 1 0 2 2 2 0 Tropomyosin MscS_porin PF12795.7 OAJ10913.1 - 0.15 11.6 9.0 1.1 8.8 8.7 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CENP-H PF05837.12 OAJ10913.1 - 0.55 10.7 5.2 0.78 10.2 4.4 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) HeH PF12949.7 OAJ10914.1 - 0.12 12.1 0.1 0.32 10.7 0.1 1.8 1 0 0 1 1 1 0 HeH/LEM domain FHA PF00498.26 OAJ10915.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 FHA domain Cutinase PF01083.22 OAJ10924.1 - 3e-16 59.9 0.0 3.7e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAJ10924.1 - 0.0079 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 OAJ10925.1 - 5.3e-08 33.0 0.0 6.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase TPP_enzyme_N PF02776.18 OAJ10926.1 - 6.4e-18 64.9 0.0 8.1e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DEAD PF00270.29 OAJ10935.1 - 3e-32 111.8 0.1 9.7e-32 110.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ10935.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRXXH PF13933.6 OAJ10936.1 - 3.8e-68 229.7 0.0 5e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAJ10936.1 - 0.06 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase INTAP PF16617.5 OAJ10937.1 - 0.079 13.3 0.0 0.099 13.0 0.0 1.2 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region DUF3385 PF11865.8 OAJ10947.1 - 4.5e-51 173.0 0.1 3e-46 157.3 0.0 4.8 4 1 2 6 6 6 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OAJ10947.1 - 1.5e-19 70.2 16.1 0.00035 20.9 0.0 10.3 8 2 1 10 10 10 4 HEAT repeats HEAT PF02985.22 OAJ10947.1 - 9.6e-15 53.4 16.5 0.64 10.4 0.1 11.3 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.6 OAJ10947.1 - 6.2e-10 39.4 24.2 0.0014 19.1 0.1 11.5 10 2 1 12 12 12 3 HEAT-like repeat UME PF08064.13 OAJ10947.1 - 1.8e-05 24.5 0.0 1.5 8.8 0.0 5.4 3 2 3 6 6 6 2 UME (NUC010) domain Cnd1 PF12717.7 OAJ10947.1 - 9.2e-05 22.5 6.3 4.2 7.4 0.0 6.1 6 2 3 9 9 9 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 OAJ10947.1 - 0.00011 22.4 2.6 0.86 9.7 0.0 5.4 4 1 1 5 5 5 1 Parkin co-regulated protein DUF3535 PF12054.8 OAJ10947.1 - 0.0021 17.4 0.6 0.16 11.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) Adaptin_N PF01602.20 OAJ10947.1 - 0.0039 15.8 7.6 0.0081 14.8 0.5 4.4 5 1 0 5 5 5 1 Adaptin N terminal region VHS PF00790.19 OAJ10947.1 - 0.054 13.3 0.1 12 5.8 0.0 3.8 4 1 1 5 5 5 0 VHS domain FdhE PF04216.12 OAJ10947.1 - 0.55 10.1 3.5 3 7.6 0.1 3.5 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation Urb2 PF10441.9 OAJ10947.1 - 0.77 9.6 3.1 2.6 7.9 0.0 3.2 3 0 0 3 3 3 0 Urb2/Npa2 family Fip1 PF05182.13 OAJ10948.1 - 4.1e-19 67.8 0.7 6.8e-19 67.1 0.7 1.4 1 0 0 1 1 1 1 Fip1 motif Lipase_GDSL PF00657.22 OAJ10949.1 - 1.9e-07 31.3 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAJ10949.1 - 0.0001 22.8 0.3 0.00029 21.3 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Retrotrans_gag PF03732.17 OAJ10957.1 - 3.9e-10 39.9 0.4 9.8e-10 38.6 0.2 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ10957.1 - 0.02 15.0 0.5 0.032 14.3 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ10957.1 - 0.024 14.4 0.6 0.052 13.4 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 OAJ10957.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) RT_RNaseH PF17917.1 OAJ10958.1 - 2.7e-35 120.8 0.0 5.6e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10958.1 - 1.3e-31 108.6 0.0 3.4e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10958.1 - 9.5e-30 103.8 0.3 1.5e-29 103.1 0.3 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ10958.1 - 1.2e-09 38.0 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ10958.1 - 3.8e-07 30.6 0.0 7.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ10958.1 - 5.9e-07 30.0 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1796 PF08795.10 OAJ10958.1 - 0.0076 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Asp_protease PF09668.10 OAJ10958.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.20 OAJ10958.1 - 0.081 13.2 0.0 0.23 11.8 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease Helitron_like_N PF14214.6 OAJ10963.1 - 7.2e-21 75.3 0.1 2.1e-20 73.8 0.0 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ10963.1 - 1.5e-18 67.2 0.0 5e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 OAJ10963.1 - 1.2e-12 47.9 0.0 2.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ10963.1 - 2.1e-07 31.3 0.0 5.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ10963.1 - 0.069 13.5 0.3 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF842 PF05811.13 OAJ10964.1 - 0.00027 20.6 0.9 0.00049 19.8 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.18 OAJ10964.1 - 0.0038 17.1 1.1 0.025 14.5 0.7 1.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Tht1 PF04163.12 OAJ10964.1 - 0.01 14.7 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein DUF2884 PF11101.8 OAJ10964.1 - 0.049 13.1 1.1 0.075 12.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Utp12 PF04003.12 OAJ10964.1 - 0.065 13.5 0.1 3.9 7.8 0.0 2.8 1 1 1 2 2 2 0 Dip2/Utp12 Family UvrD_C_2 PF13538.6 OAJ10966.1 - 0.036 13.9 3.1 0.14 12.0 3.1 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PPI_Ypi1 PF07491.11 OAJ10967.1 - 0.19 11.6 0.2 0.51 10.2 0.2 1.7 1 0 0 1 1 1 0 Protein phosphatase inhibitor DPPIV_N PF00930.21 OAJ10977.1 - 1.8e-73 247.3 0.0 3.6e-72 243.1 0.0 2.4 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAJ10977.1 - 9.7e-43 146.1 0.5 1.5e-42 145.5 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAJ10977.1 - 0.00057 19.6 0.8 0.003 17.2 0.7 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAJ10977.1 - 0.031 12.9 0.0 0.14 10.8 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) GRP PF07172.11 OAJ10978.1 - 0.031 14.9 15.1 0.13 13.0 5.3 3.5 3 0 0 3 3 3 0 Glycine rich protein family PRK PF00485.18 OAJ10979.1 - 8.4e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OAJ10979.1 - 1.8e-05 25.3 0.0 8.3e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 OAJ10979.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 OAJ10979.1 - 0.19 12.1 0.2 11 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ10979.1 - 0.29 11.3 0.9 0.75 10.0 0.9 1.9 1 1 0 1 1 1 0 AAA domain Plant_tran PF04827.14 OAJ10986.1 - 0.0075 15.9 0.0 0.0092 15.6 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 OAJ10986.1 - 0.023 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease SOG2 PF10428.9 OAJ10993.1 - 0.00053 19.3 7.1 0.00069 18.9 7.1 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein SPX PF03105.19 OAJ10993.1 - 0.0056 16.7 1.4 0.0089 16.0 1.4 1.4 1 1 0 1 1 1 1 SPX domain Herpes_UL6 PF01763.16 OAJ10993.1 - 0.025 13.1 0.0 1.2 7.6 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL6 like zf-C2H2 PF00096.26 OAJ10994.1 - 1.2e-05 25.5 3.5 1.2e-05 25.5 3.5 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-BED PF02892.15 OAJ10994.1 - 8.4e-05 22.5 2.1 8.4e-05 22.5 2.1 2.6 3 0 0 3 3 3 1 BED zinc finger zf-C2H2_4 PF13894.6 OAJ10994.1 - 0.00033 21.2 2.2 0.00033 21.2 2.2 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger Zn_Tnp_IS1595 PF12760.7 OAJ10994.1 - 0.032 14.2 1.9 2 8.5 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-MYST PF17772.1 OAJ10994.1 - 0.032 13.8 0.3 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain zf-met PF12874.7 OAJ10994.1 - 0.062 13.7 0.6 0.21 12.0 0.6 2.0 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 OAJ10994.1 - 0.082 13.2 2.3 0.21 11.9 0.2 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 OAJ10994.1 - 0.15 11.8 8.9 0.04 13.7 3.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF629 PF04780.12 OAJ10994.1 - 0.27 9.7 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 OAJ10994.1 - 0.28 11.7 2.5 3.1 8.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Rubredoxin_2 PF18073.1 OAJ10994.1 - 1.4 8.7 6.7 4.6 7.1 1.9 2.7 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 OAJ10994.1 - 2 7.9 5.5 6.9 6.2 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 OAJ10994.1 - 2.6 7.9 6.2 0.86 9.4 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-RRN7 PF11781.8 OAJ10994.1 - 3.6 7.4 5.5 27 4.6 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn_ribbon_SprT PF17283.2 OAJ10994.1 - 4.8 7.2 7.9 3.2 7.7 1.3 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 OAJ10994.1 - 4.9 7.0 10.8 0.14 11.9 3.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RT_RNaseH PF17917.1 OAJ10995.1 - 1.1e-38 131.8 0.1 1.9e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10995.1 - 1.1e-36 124.8 0.0 2.2e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10995.1 - 1.6e-21 76.1 0.1 4.7e-21 74.7 0.1 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10995.1 - 8.1e-16 58.3 0.0 6.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ10995.1 - 7.4e-11 42.0 0.1 1.2e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 OAJ10995.1 - 7.9e-05 22.8 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Retrotrans_gag PF03732.17 OAJ10996.1 - 1.2e-11 44.7 0.0 1.4e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ10996.1 - 8.1e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) RVT_1 PF00078.27 OAJ10996.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NTP_transf_2 PF01909.23 OAJ11004.1 - 0.08 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain UPF0767 PF15990.5 OAJ11005.1 - 4.9 7.4 5.0 13 6.0 4.7 2.0 1 1 0 1 1 1 0 UPF0767 family DDE_Tnp_4 PF13359.6 OAJ11006.1 - 1.7e-16 60.3 0.0 3.6e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ11006.1 - 0.0094 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Herpes_U44 PF04533.13 OAJ11006.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpes virus U44 protein DUF3619 PF12279.8 OAJ11007.1 - 0.075 13.4 1.0 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) RT_RNaseH_2 PF17919.1 OAJ11025.1 - 6.2e-15 55.0 0.0 3.3e-14 52.7 0.0 2.2 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11025.1 - 2e-14 53.4 0.0 3.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11025.1 - 8.1e-12 45.4 0.0 2.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ11025.1 - 0.0073 16.6 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ11026.1 - 2.7e-07 30.3 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ11026.1 - 2e-05 25.1 0.1 4.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11026.1 - 0.00068 20.2 0.0 0.0026 18.3 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2849 PF11011.8 OAJ11026.1 - 0.0036 17.9 0.0 0.51 11.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2849) DUF2313 PF10076.9 OAJ11026.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) A_deaminase PF00962.22 OAJ11036.1 - 9.3e-120 399.9 0.1 1.3e-119 399.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPT PF03151.16 OAJ11037.1 - 8.8e-49 166.4 15.4 4.2e-48 164.2 12.9 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ11037.1 - 3e-11 43.7 26.1 6.3e-06 26.4 12.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAJ11037.1 - 0.0001 21.6 16.0 0.00033 20.0 16.0 1.7 1 1 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 OAJ11037.1 - 1.9 9.2 10.2 0.22 12.2 5.3 2.0 2 0 0 2 2 2 0 Small Multidrug Resistance protein PX PF00787.24 OAJ11038.1 - 1.1e-09 38.2 0.0 2.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 PX domain NOA36 PF06524.12 OAJ11038.1 - 7.8 5.7 5.2 1.5 8.0 0.3 2.0 2 0 0 2 2 2 0 NOA36 protein 4HBT PF03061.22 OAJ11039.1 - 7.4e-09 35.8 0.1 1.6e-08 34.8 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily Helicase_C PF00271.31 OAJ11040.1 - 8.1e-34 116.3 0.0 3e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ11040.1 - 2.1e-29 102.5 0.1 4.3e-29 101.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase CMS1 PF14617.6 OAJ11040.1 - 0.069 12.5 0.1 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Thioredoxin PF00085.20 OAJ11048.1 - 1.9e-17 63.1 0.0 2.2e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ11048.1 - 0.002 18.6 0.0 0.003 18.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ11048.1 - 0.0024 18.2 0.0 0.087 13.2 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 OAJ11048.1 - 0.0025 17.2 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 OAJ11048.1 - 0.06 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Crystall_2 PF09076.10 OAJ11048.1 - 0.098 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin FCH PF00611.23 OAJ11049.1 - 4.9e-15 55.6 3.1 5.1e-15 55.5 0.1 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 OAJ11049.1 - 7.6e-11 41.4 0.0 1.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ11049.1 - 2.4e-08 33.7 0.0 5.9e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 OAJ11049.1 - 1e-07 31.5 0.0 2.8e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SUIM_assoc PF16619.5 OAJ11049.1 - 0.01 15.9 2.2 0.01 15.9 2.2 9.4 10 0 0 10 10 10 0 Unstructured region C-term to UIM in Ataxin3 Abhydrolase_1 PF00561.20 OAJ11050.1 - 5.1e-13 49.3 0.1 4.6e-09 36.3 0.3 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ11050.1 - 8.7e-13 48.1 0.1 9.7e-12 44.7 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ11050.1 - 2.1e-11 44.8 0.6 3e-11 44.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 OAJ11050.1 - 7.6e-10 37.9 0.1 2e-05 23.4 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 OAJ11050.1 - 5.7e-09 35.8 0.0 2.2e-07 30.6 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAJ11050.1 - 7.4e-09 35.6 0.0 9.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAJ11050.1 - 1.8e-08 34.2 0.0 3.6e-07 29.9 0.1 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAJ11050.1 - 6.9e-06 26.1 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 OAJ11050.1 - 0.00061 18.4 0.1 0.65 8.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 OAJ11050.1 - 0.0018 18.0 0.1 0.024 14.3 0.1 2.2 1 1 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 OAJ11050.1 - 0.0027 16.6 0.0 0.0039 16.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF1100 PF06500.11 OAJ11050.1 - 0.0075 15.1 0.0 0.029 13.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 OAJ11050.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-C3HC4_3 PF13920.6 OAJ11051.1 - 0.11 12.4 8.2 0.2 11.5 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SPX PF03105.19 OAJ11051.1 - 2.4 8.0 16.5 0.16 11.8 2.7 2.4 2 0 0 2 2 2 0 SPX domain MMM1 PF10296.9 OAJ11067.1 - 0.11 11.6 0.0 0.27 10.2 0.0 1.4 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Sugar_tr PF00083.24 OAJ11068.1 - 1.8e-28 99.6 23.4 3.1e-23 82.4 17.9 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ11068.1 - 2.7e-13 49.6 37.1 1.3e-08 34.1 16.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 OAJ11068.1 - 0.013 14.1 16.4 0.21 10.2 13.2 2.6 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like Cation_efflux PF01545.21 OAJ11068.1 - 0.066 12.9 9.3 0.52 10.0 5.9 2.6 2 1 0 2 2 2 0 Cation efflux family TPR_2 PF07719.17 OAJ11069.1 - 1e-10 40.9 21.6 0.14 12.3 0.1 10.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ11069.1 - 2e-09 36.9 3.7 1.4 8.9 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ11069.1 - 8.7e-09 35.9 30.6 0.0015 19.2 1.2 8.7 9 1 0 9 9 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ11069.1 - 2.3e-07 31.0 22.0 0.0035 17.6 1.9 8.1 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ11069.1 - 3e-07 30.8 18.3 3.5e-05 24.2 2.1 6.9 7 2 3 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ11069.1 - 1.7e-06 28.3 12.5 1.7 9.5 0.1 9.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ11069.1 - 4.7e-06 26.3 12.5 1 9.5 0.2 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat BTAD PF03704.17 OAJ11069.1 - 7.6e-06 26.4 10.2 0.00064 20.2 0.6 3.6 3 1 0 3 3 2 2 Bacterial transcriptional activator domain TPR_8 PF13181.6 OAJ11069.1 - 4.2e-05 23.4 5.7 2.2 8.7 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ11069.1 - 0.00026 21.6 32.6 0.095 13.6 0.6 10.9 8 2 4 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ11069.1 - 0.003 17.8 0.3 3 8.4 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ11069.1 - 0.003 17.9 5.1 0.079 13.3 0.4 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ11069.1 - 0.0035 17.0 6.6 6.8 6.5 0.1 6.0 6 0 0 6 6 6 1 TPR repeat ANAPC3 PF12895.7 OAJ11069.1 - 0.0036 17.5 14.4 0.031 14.5 0.5 5.8 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ11069.1 - 0.0043 17.2 17.3 2.5 8.3 1.0 7.3 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ11069.1 - 0.0054 17.2 7.7 0.43 11.4 0.2 6.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ11069.1 - 0.0088 15.9 9.2 21 5.2 0.2 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat CDC50 PF03381.15 OAJ11076.1 - 1.8e-86 290.1 0.0 2.3e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF382 PF04037.13 OAJ11078.1 - 2.3e-54 183.0 0.1 4.6e-54 182.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 OAJ11078.1 - 2e-18 65.9 3.7 5.4e-18 64.6 3.7 1.8 1 0 0 1 1 1 1 PSP Nucleo_P87 PF07267.11 OAJ11078.1 - 2.1 7.1 13.0 1.6 7.5 4.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 OAJ11078.1 - 5.9 7.3 17.3 3.2 8.2 4.3 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPX PF03105.19 OAJ11087.1 - 0.073 13.0 15.1 0.24 11.2 14.5 2.0 1 1 1 2 2 2 0 SPX domain DUF2244 PF10003.9 OAJ11087.1 - 0.085 12.5 1.0 0.19 11.4 1.0 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) SWIRM-assoc_2 PF16496.5 OAJ11087.1 - 0.16 10.8 5.3 0.26 10.1 5.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal MutS_IV PF05190.18 OAJ11088.1 - 0.0034 17.7 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV DnaJ-X PF14308.6 OAJ11102.1 - 6.7e-49 166.2 0.8 6.7e-49 166.2 0.8 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ11102.1 - 8.6e-25 86.6 0.3 8.6e-25 86.6 0.3 2.3 3 0 0 3 3 3 1 DnaJ domain HA2 PF04408.23 OAJ11102.1 - 0.1 12.9 2.3 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) Tmemb_55A PF09788.9 OAJ11102.1 - 0.16 11.0 0.6 0.37 9.8 0.6 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A NOG1_N PF17835.1 OAJ11102.1 - 5.3 7.0 7.3 3.6 7.5 1.1 2.7 2 0 0 2 2 2 0 NOG1 N-terminal helical domain MFS_1 PF07690.16 OAJ11104.1 - 2.6e-38 131.8 51.5 2.6e-38 131.8 51.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ11104.1 - 1.2e-11 44.2 9.2 1.2e-11 44.2 9.2 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter NAD_binding_8 PF13450.6 OAJ11105.1 - 4.6e-14 52.4 0.0 1.7e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ11105.1 - 0.0029 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ11105.1 - 0.086 12.1 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ACTH_assoc PF16102.5 OAJ11105.1 - 0.13 13.1 0.6 5.9 7.9 0.0 3.2 2 0 0 2 2 2 0 ACTH-associated domain Lipase_3 PF01764.25 OAJ11111.1 - 8.6e-08 32.1 0.1 5.7e-07 29.5 0.1 2.2 2 0 0 2 2 2 1 Lipase (class 3) Nudix_N PF12535.8 OAJ11112.1 - 0.1 12.2 0.3 1.1e+02 2.5 0.0 3.5 4 0 0 4 4 4 0 Hydrolase of X-linked nucleoside diphosphate N terminal LrgB PF04172.16 OAJ11112.1 - 0.19 11.2 7.6 4.6 6.7 0.1 3.0 3 0 0 3 3 3 0 LrgB-like family Anti-TRAP PF15777.5 OAJ11112.1 - 0.68 9.9 2.6 80 3.3 0.1 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Lipase_3 PF01764.25 OAJ11113.1 - 2.7e-12 46.8 0.0 1.1e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) DUF2273 PF10031.9 OAJ11114.1 - 0.0013 18.7 2.7 0.0031 17.5 2.7 1.7 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) TrbC PF04956.13 OAJ11114.1 - 0.7 10.1 2.3 6 7.2 1.0 2.5 2 1 0 2 2 2 0 TrbC/VIRB2 family MtrF PF09472.10 OAJ11114.1 - 4.9 6.6 5.2 0.64 9.5 0.6 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ABC_ATPase PF09818.9 OAJ11122.1 - 3.2e-137 458.0 0.0 8.9e-137 456.5 0.0 1.6 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 OAJ11122.1 - 0.21 12.1 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 OAJ11122.1 - 0.29 10.3 0.4 2.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) KH_1 PF00013.29 OAJ11123.1 - 1.4e-34 117.7 1.5 1.1e-08 34.7 0.0 6.3 6 0 0 6 6 6 4 KH domain DUF4407 PF14362.6 OAJ11123.1 - 5.2 6.3 19.2 2.7 7.3 4.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PRP3 PF08572.10 OAJ11123.1 - 9.8 5.8 16.2 0.13 12.0 5.5 2.4 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Ribosomal_L32p PF01783.23 OAJ11124.1 - 2.9e-14 53.0 7.5 4.3e-14 52.5 6.6 1.8 2 0 0 2 2 2 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 OAJ11124.1 - 0.012 15.6 1.0 0.023 14.6 1.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Tape_meas_lam_C PF09718.10 OAJ11124.1 - 0.05 13.7 0.3 0.05 13.7 0.3 1.8 2 1 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) GcpE PF04551.14 OAJ11124.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 GcpE protein EF-hand_6 PF13405.6 OAJ11125.1 - 5e-07 29.1 0.4 0.015 15.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAJ11125.1 - 1.6e-06 28.5 0.6 5.2e-06 26.8 0.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAJ11125.1 - 4.2e-06 26.0 0.1 0.045 13.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OAJ11125.1 - 0.0014 18.0 0.6 1.1 8.9 0.1 2.6 2 0 0 2 2 2 2 EF hand OCRE PF17780.1 OAJ11125.1 - 0.045 13.8 0.4 0.1 12.6 0.4 1.6 1 0 0 1 1 1 0 OCRE domain DUF3040 PF11239.8 OAJ11125.1 - 0.28 11.5 2.1 16 5.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) SPARC_Ca_bdg PF10591.9 OAJ11125.1 - 4.9 7.5 10.7 4.2 7.7 0.2 4.0 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Nkap_C PF06047.11 OAJ11126.1 - 8.8e-45 151.0 5.3 8.8e-45 151.0 5.3 2.0 2 1 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Hfx_Cass5 PF18287.1 OAJ11132.1 - 0.02 15.1 0.0 6.5 7.0 0.0 2.2 1 1 1 2 2 2 0 Integron Cassette Protein Hfx_Cass5 Adhesin_P1_N PF18652.1 OAJ11132.1 - 0.12 12.4 0.7 0.89 9.6 0.2 2.0 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain SR-25 PF10500.9 OAJ11133.1 - 2.4 7.7 11.3 4 7.0 11.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ferritin_2 PF13668.6 OAJ11135.1 - 5.4e-09 36.4 0.0 8.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Asp PF00026.23 OAJ11136.1 - 6.3e-15 55.4 0.1 9.7e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF5507 PF17612.2 OAJ11136.1 - 0.2 11.4 0.2 7.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5507) Glyco_tran_28_C PF04101.16 OAJ11141.1 - 4.2e-21 75.6 0.0 5.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CheB_methylest PF01339.17 OAJ11141.1 - 0.00042 20.1 0.1 0.00059 19.6 0.1 1.1 1 0 0 1 1 1 1 CheB methylesterase DEAD PF00270.29 OAJ11141.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase ubiquitin PF00240.23 OAJ11142.1 - 8.8e-08 31.8 0.1 1.5e-07 31.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ11142.1 - 1e-05 25.9 0.1 7.4e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OAJ11142.1 - 0.00063 19.5 0.0 0.0007 19.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OAJ11142.1 - 0.061 13.4 0.0 0.33 11.0 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Ribosomal_S24e PF01282.19 OAJ11142.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e RAWUL PF16207.5 OAJ11142.1 - 0.14 12.8 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like FHA PF00498.26 OAJ11143.1 - 5.2e-16 58.7 0.0 1.4e-15 57.4 0.0 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ11143.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Macoilin PF09726.9 OAJ11143.1 - 0.58 8.6 0.0 0.58 8.6 0.0 3.6 3 1 0 3 3 3 0 Macoilin family Ribonucleas_3_3 PF14622.6 OAJ11144.1 - 1.3e-20 73.8 0.1 2.3e-20 73.0 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like SPX PF03105.19 OAJ11144.1 - 0.62 9.9 4.4 0.75 9.6 4.4 1.1 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 OAJ11144.1 - 5.6 6.5 11.7 9.9 5.7 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAI16-like PF10257.9 OAJ11145.1 - 6.1e-52 176.7 0.0 9.4e-51 172.8 0.0 2.2 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein PBP1_TM PF14812.6 OAJ11145.1 - 0.15 12.4 26.3 0.59 10.5 6.5 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 OAJ11145.1 - 0.21 11.4 13.7 0.15 11.9 1.9 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region RRN3 PF05327.11 OAJ11145.1 - 0.34 9.4 8.5 0.29 9.6 1.3 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 OAJ11145.1 - 0.39 10.5 5.5 0.55 10.0 0.5 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GCIP PF13324.6 OAJ11145.1 - 0.41 10.2 6.9 4.9 6.7 1.1 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PTPRCAP PF15713.5 OAJ11145.1 - 1 9.6 13.2 16 5.8 6.4 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 OAJ11145.1 - 1.3 8.6 9.1 0.24 11.0 1.0 2.5 2 0 0 2 2 2 0 PPP4R2 Cnd2 PF05786.14 OAJ11145.1 - 2.4 6.7 8.7 1.5 7.4 0.4 2.3 2 0 0 2 2 2 0 Condensin complex subunit 2 PI3K_1B_p101 PF10486.9 OAJ11145.1 - 3.8 5.2 3.9 6.6 4.4 3.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2457 PF10446.9 OAJ11145.1 - 5 6.2 31.0 0.31 10.1 11.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 OAJ11145.1 - 5.9 6.5 13.2 13 5.4 0.7 2.6 2 0 0 2 2 2 0 FAM176 family BUD22 PF09073.10 OAJ11145.1 - 8.9 5.5 20.0 0.014 14.7 2.1 3.2 3 0 0 3 3 3 0 BUD22 CFIA_Pcf11 PF11526.8 OAJ11145.1 - 9.7 6.8 7.1 2.3 8.7 1.7 2.9 2 0 0 2 2 1 0 Subunit of cleavage factor IA Pcf11 Brix PF04427.18 OAJ11155.1 - 2.2e-21 76.8 0.0 3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Trypan_PARP PF05887.11 OAJ11155.1 - 0.42 10.6 26.4 1.2 9.2 17.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BUD22 PF09073.10 OAJ11155.1 - 1.5 8.1 32.7 0.016 14.6 23.5 2.0 2 0 0 2 2 2 0 BUD22 RRN3 PF05327.11 OAJ11155.1 - 3.4 6.1 12.8 5.8 5.3 12.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PAXNEB PF05625.11 OAJ11156.1 - 3.4e-31 108.7 0.0 2.3e-28 99.4 0.0 2.7 2 1 0 2 2 2 2 PAXNEB protein polyprenyl_synt PF00348.17 OAJ11157.1 - 9.6e-62 208.3 0.0 3e-35 121.5 0.0 3.2 2 2 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OAJ11157.1 - 0.12 12.0 0.3 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 HEAT_PBS PF03130.16 OAJ11157.1 - 0.45 11.3 3.6 36 5.4 0.1 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Clat_adaptor_s PF01217.20 OAJ11158.1 - 2.3e-54 183.2 0.2 2.7e-54 183.0 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1g PF09334.11 OAJ11159.1 - 4.5e-154 512.9 0.1 5.5e-154 512.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 OAJ11159.1 - 7.4e-07 29.2 3.4 7.4e-07 29.2 3.4 2.2 1 1 1 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 OAJ11159.1 - 1.2e-06 27.1 1.7 0.00013 20.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Zn-ribbon_8 PF09723.10 OAJ11159.1 - 0.093 12.9 2.1 2.2 8.5 0.6 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 OAJ11159.1 - 0.35 10.9 5.4 0.63 10.1 4.4 1.8 1 1 1 2 2 2 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OAJ11159.1 - 4.3 6.9 5.5 26 4.4 0.1 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 OAJ11159.1 - 7 6.2 6.2 30 4.2 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain NmrA PF05368.13 OAJ11166.1 - 8.7e-14 51.6 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ11166.1 - 4.9e-09 36.3 0.0 7.3e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAJ11166.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 OAJ11167.1 - 1.2e-14 54.1 0.0 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ11167.1 - 1.8e-08 34.3 9.6 3.4e-08 33.5 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3091 PF11291.8 OAJ11168.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) DUF913 PF06025.12 OAJ11169.1 - 0.01 14.8 0.2 1.5 7.8 0.4 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MFS_1 PF07690.16 OAJ11170.1 - 5.6e-37 127.5 10.9 6e-37 127.4 10.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ11170.1 - 2.2e-10 40.0 2.2 4.5e-10 39.0 2.2 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ11170.1 - 0.00016 20.7 4.7 0.016 14.0 0.0 3.2 2 1 1 3 3 3 2 MFS_1 like family MFS_4 PF06779.14 OAJ11170.1 - 0.029 13.7 6.4 0.072 12.4 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAJ11170.1 - 0.064 11.7 0.3 0.1 11.0 0.3 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Transposase_21 PF02992.14 OAJ11181.1 - 2.2e-12 46.7 0.0 5.9e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.12 OAJ11181.1 - 0.023 14.2 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) Spc7 PF08317.11 OAJ11182.1 - 0.0014 17.6 11.9 0.0014 17.6 11.9 2.4 1 1 1 2 2 2 1 Spc7 kinetochore protein Med21 PF11221.8 OAJ11182.1 - 0.0074 16.6 3.4 0.0074 16.6 3.4 3.4 2 1 1 3 3 3 1 Subunit 21 of Mediator complex ATG16 PF08614.11 OAJ11182.1 - 0.011 15.9 11.6 0.011 15.9 11.6 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF2370 PF10176.9 OAJ11182.1 - 0.1 12.2 0.4 0.21 11.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MbeD_MobD PF04899.12 OAJ11182.1 - 0.18 12.0 4.9 0.27 11.4 3.0 2.4 2 1 0 2 2 2 0 MbeD/MobD like Cnn_1N PF07989.11 OAJ11182.1 - 0.21 11.7 26.2 0.81 9.9 9.2 4.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 GCN5L1 PF06320.13 OAJ11182.1 - 2.5 8.3 17.1 0.048 13.8 5.5 3.0 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) ZapB PF06005.12 OAJ11182.1 - 3.8 8.0 36.0 0.068 13.6 4.0 4.4 2 1 2 4 4 4 0 Cell division protein ZapB YabA PF06156.13 OAJ11182.1 - 7.1 7.3 19.6 8.9 7.0 1.6 3.8 1 1 2 3 3 3 0 Initiation control protein YabA DUF1722 PF08349.11 OAJ11182.1 - 8.3 6.7 7.6 6.4 7.1 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) DBD_Tnp_Hermes PF10683.9 OAJ11183.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain GREB1 PF15782.5 OAJ11184.1 - 9.5 3.2 11.9 13 2.8 11.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AGH PF17558.2 OAJ11185.1 - 0.00043 20.4 1.3 0.00043 20.4 1.3 2.1 1 1 1 2 2 2 1 Androgenic gland hormone Nop14 PF04147.12 OAJ11185.1 - 0.039 12.2 12.1 0.044 12.0 12.1 1.0 1 0 0 1 1 1 0 Nop14-like family Trypan_PARP PF05887.11 OAJ11185.1 - 0.044 13.8 2.2 0.057 13.4 2.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_pol_3_Rpc31 PF11705.8 OAJ11185.1 - 0.059 13.6 10.7 0.088 13.1 10.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 OAJ11185.1 - 0.12 12.3 2.3 0.17 11.8 2.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 OAJ11185.1 - 0.13 11.6 16.4 0.16 11.3 16.4 1.0 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 OAJ11185.1 - 0.84 8.5 3.0 1.1 8.2 3.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 OAJ11185.1 - 2.9 6.6 4.6 3.2 6.4 4.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 OAJ11185.1 - 4 6.8 19.7 4.9 6.5 19.7 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ11185.1 - 6.1 5.0 10.5 7.1 4.8 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 OAJ11185.1 - 8.4 5.5 7.7 11 5.1 7.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Dimer_Tnp_hAT PF05699.14 OAJ11186.1 - 1.9e-11 43.6 0.0 5.2e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RNA_pol_3_Rpc31 PF11705.8 OAJ11186.1 - 0.48 10.7 9.4 0.15 12.3 5.3 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 GEN1_C PF18380.1 OAJ11186.1 - 3.8 8.4 7.4 0.67 10.9 0.4 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Histone PF00125.24 OAJ11187.1 - 3e-45 153.8 3.7 3.3e-45 153.7 3.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ11187.1 - 3.8e-05 23.8 0.2 0.00012 22.1 0.1 1.7 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ11187.1 - 0.00014 22.1 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ11187.1 - 0.016 15.5 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cellulase PF00150.18 OAJ11193.1 - 8e-06 25.5 0.7 1.4e-05 24.7 0.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) YoeB_toxin PF06769.14 OAJ11193.1 - 0.087 12.9 0.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system NDC10_II PF16787.5 OAJ11194.1 - 3.2e-43 148.0 0.0 5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ11194.1 - 0.041 14.2 0.2 0.099 13.0 0.2 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes DUF1216 PF06746.11 OAJ11194.1 - 1.6 8.8 4.1 4 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) Ricin_B_lectin PF00652.22 OAJ11195.1 - 0.048 13.9 0.0 0.07 13.4 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF4746 PF15928.5 OAJ11196.1 - 0.03 13.7 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) Helitron_like_N PF14214.6 OAJ11201.1 - 7.2e-05 23.1 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-C2HC5 PF06221.13 OAJ11201.1 - 0.33 11.0 1.1 0.6 10.1 1.1 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SRP-alpha_N PF04086.13 OAJ11203.1 - 1.2 9.0 19.2 1.5 8.7 19.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4381 PF14316.6 OAJ11203.1 - 1.4 9.2 5.9 2.2 8.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMEM119 PF15724.5 OAJ11203.1 - 1.8 8.6 6.3 2.1 8.3 6.3 1.2 1 0 0 1 1 1 0 TMEM119 family PIF1 PF05970.14 OAJ11205.1 - 1.1e-52 179.4 0.0 1.8e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ11205.1 - 5.8e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ11205.1 - 0.00013 22.4 0.0 0.00053 20.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 OAJ11205.1 - 0.079 13.4 0.1 0.3 11.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ParD PF09386.10 OAJ11211.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Antitoxin ParD LcrR PF09621.10 OAJ11211.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Retrotrans_gag PF03732.17 OAJ11212.1 - 0.003 17.8 0.1 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Pex19 PF04614.12 OAJ11217.1 - 3.9e-58 197.1 1.3 1.5e-57 195.2 0.0 1.9 1 1 1 2 2 2 1 Pex19 protein family ORC6 PF05460.13 OAJ11217.1 - 0.04 13.2 0.2 0.055 12.7 0.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SLX9 PF15341.6 OAJ11217.1 - 0.23 11.8 2.3 1.9 8.9 0.9 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 CCDC53 PF10152.9 OAJ11217.1 - 2.7 8.4 6.0 0.66 10.4 2.0 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ALAD PF00490.21 OAJ11218.1 - 3.7e-121 404.2 0.0 4.4e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Cation_ATPase_C PF00689.21 OAJ11219.1 - 3.5e-48 163.7 5.7 1.3e-47 161.9 2.5 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ11219.1 - 8.4e-48 162.3 1.8 8.4e-48 162.3 1.8 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ11219.1 - 9.7e-26 91.4 1.0 5.3e-25 88.9 1.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ11219.1 - 2.1e-19 69.0 0.0 4.5e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ11219.1 - 6.3e-18 64.6 0.0 1.2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 OAJ11219.1 - 4.3e-07 30.5 0.0 9.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ11219.1 - 2.5e-06 27.4 0.7 4.2e-05 23.4 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TraL PF07178.11 OAJ11219.1 - 0.52 10.8 2.6 1.4 9.4 0.1 2.8 2 0 0 2 2 2 0 TraL protein MPC PF03650.13 OAJ11220.1 - 2e-35 121.3 0.1 2.6e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers GARS_N PF02844.15 OAJ11220.1 - 0.056 14.2 0.0 0.091 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain RNA_pol_3_Rpc31 PF11705.8 OAJ11221.1 - 4.2e-26 92.6 5.4 6.9e-26 91.9 5.4 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 ETF PF01012.21 OAJ11225.1 - 1.1e-40 139.5 9.3 1.7e-40 138.8 9.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAJ11225.1 - 9.7e-33 112.1 0.7 9.7e-33 112.1 0.7 2.4 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain Alginate_lyase PF05426.12 OAJ11227.1 - 4.5e-49 167.4 4.6 1.6e-47 162.4 1.4 2.3 2 0 0 2 2 2 2 Alginate lyase RVT_1 PF00078.27 OAJ11233.1 - 6.2e-23 81.5 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11233.1 - 2e-20 72.7 0.0 1.1e-12 47.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11233.1 - 1.3e-14 54.4 0.0 7.6e-10 39.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11233.1 - 9.5e-13 48.4 0.0 2.2e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ11233.1 - 2.2e-11 43.7 0.0 3.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ11233.1 - 0.0018 18.9 0.0 0.0075 16.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11233.1 - 0.14 12.7 0.0 0.52 10.9 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MitMem_reg PF13012.6 OAJ11240.1 - 0.13 12.7 0.3 0.51 10.8 0.2 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF4381 PF14316.6 OAJ11241.1 - 0.00031 21.0 0.2 0.00047 20.4 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4381) eIF2_C PF09173.11 OAJ11242.1 - 7.7e-37 125.4 0.5 2e-36 124.1 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAJ11242.1 - 9.2e-22 77.5 0.8 9.8e-21 74.2 0.8 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ11242.1 - 8.6e-12 45.3 1.7 1.1e-11 44.9 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OAJ11242.1 - 0.00044 20.2 0.3 0.0052 16.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OAJ11242.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAJ11242.1 - 0.026 14.5 0.9 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Asp_Glu_race PF01177.22 OAJ11243.1 - 7.1e-08 32.6 0.2 5.5e-07 29.7 0.2 2.0 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase RNase_P_pop3 PF08228.11 OAJ11244.1 - 0.0018 18.3 0.3 0.8 9.7 0.0 2.6 3 0 0 3 3 3 2 RNase P subunit Pop3 HBS1_N PF08938.10 OAJ11250.1 - 0.075 13.3 1.9 8.1 6.8 0.3 2.4 1 1 1 2 2 2 0 HBS1 N-terminus Mus7 PF09462.10 OAJ11250.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Mus7/MMS22 family Cofilin_ADF PF00241.20 OAJ11251.1 - 1.8e-39 134.3 0.2 2e-39 134.1 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LRR_6 PF13516.6 OAJ11252.1 - 2.8e-16 58.1 28.6 0.0019 18.1 0.1 10.2 10 0 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.6 OAJ11252.1 - 0.0028 17.4 17.6 3.4 7.5 0.0 6.4 3 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OAJ11252.1 - 0.06 13.8 26.1 2.4 8.7 0.6 7.2 4 3 4 9 9 9 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ11252.1 - 3.2 8.7 19.7 52 5.0 0.1 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat Isy1 PF06246.12 OAJ11252.1 - 5.4 6.5 13.4 0.0087 15.7 1.6 2.3 3 0 0 3 3 3 0 Isy1-like splicing family Tyrosinase PF00264.20 OAJ11253.1 - 1.6e-36 126.7 3.1 2.2e-36 126.2 3.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_48 PF02011.15 OAJ11254.1 - 0.61 8.6 1.8 0.72 8.3 1.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 SSFA2_C PF14723.6 OAJ11254.1 - 7.8 6.4 6.7 9.8 6.0 6.7 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF3287 PF11690.8 OAJ11262.1 - 0.00072 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3287) Dynactin PF12455.8 OAJ11264.1 - 1.5e-56 191.8 2.1 1.5e-56 191.8 2.1 4.5 4 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 OAJ11264.1 - 4.7e-21 74.6 0.8 9.4e-21 73.6 0.8 1.5 1 0 0 1 1 1 1 CAP-Gly domain Fez1 PF06818.15 OAJ11264.1 - 0.001 19.6 7.8 0.001 19.6 7.8 5.7 4 1 0 4 4 4 1 Fez1 HOOK PF05622.12 OAJ11264.1 - 1.7 6.7 84.3 0.0035 15.6 16.2 3.6 2 1 1 3 3 3 0 HOOK protein Pyr_redox_2 PF07992.14 OAJ11265.1 - 1.4e-07 31.0 0.0 3.4e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ11265.1 - 4.1e-05 23.0 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ11265.1 - 0.0011 18.2 0.0 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ11265.1 - 0.0021 18.0 1.9 0.042 13.8 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 OAJ11265.1 - 0.011 15.8 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 OAJ11265.1 - 0.011 14.9 0.4 0.019 14.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAJ11265.1 - 0.033 12.9 2.5 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 OAJ11265.1 - 0.042 13.3 0.3 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus PRC PF05239.16 OAJ11265.1 - 0.14 12.3 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 PRC-barrel domain FAD_oxidored PF12831.7 OAJ11265.1 - 0.17 11.2 1.3 0.23 10.8 1.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 OAJ11265.1 - 0.25 10.4 2.5 1.7 7.6 2.5 2.0 1 1 0 1 1 1 0 Glucose inhibited division protein A ASD2 PF08687.11 OAJ11286.1 - 0.025 14.2 6.4 0.029 13.9 6.4 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 TFIIA PF03153.13 OAJ11286.1 - 0.044 13.8 18.1 0.045 13.8 18.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 OAJ11286.1 - 0.05 13.7 5.1 0.053 13.7 5.1 1.1 1 0 0 1 1 1 0 DDHD domain API5 PF05918.11 OAJ11286.1 - 0.059 12.2 10.1 0.072 11.9 10.1 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RR_TM4-6 PF06459.12 OAJ11286.1 - 0.073 12.9 4.8 0.078 12.8 4.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 OAJ11286.1 - 0.087 13.5 16.6 0.11 13.2 16.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PP31 PF05311.11 OAJ11286.1 - 0.1 12.1 5.2 0.12 11.9 5.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Kei1 PF08552.11 OAJ11286.1 - 0.17 11.8 5.1 0.18 11.7 5.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Velvet PF11754.8 OAJ11286.1 - 0.18 11.7 10.9 0.21 11.5 10.9 1.1 1 0 0 1 1 1 0 Velvet factor Suf PF05843.14 OAJ11286.1 - 0.19 11.7 10.9 0.22 11.5 10.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Coilin_N PF15862.5 OAJ11286.1 - 0.46 10.3 9.9 0.57 10.0 9.9 1.1 1 0 0 1 1 1 0 Coilin N-terminus CLN3 PF02487.17 OAJ11286.1 - 0.53 9.3 4.3 0.57 9.2 4.3 1.1 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 OAJ11286.1 - 0.63 10.2 6.1 0.75 10.0 6.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Conotoxin PF02950.17 OAJ11286.1 - 0.77 10.8 12.0 0.57 11.2 10.3 1.6 1 1 1 2 2 2 0 Conotoxin DAG_kinase_N PF14513.6 OAJ11286.1 - 1 9.6 9.7 1.2 9.3 9.7 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus CCDC53 PF10152.9 OAJ11286.1 - 1.2 9.6 11.1 1.5 9.3 11.1 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Hydin_ADK PF17213.3 OAJ11286.1 - 1.3 9.3 10.2 1.5 9.0 10.2 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Spt20 PF12090.8 OAJ11286.1 - 1.4 8.4 22.9 1.9 8.0 22.9 1.2 1 0 0 1 1 1 0 Spt20 family RNA_pol_Rpc4 PF05132.14 OAJ11286.1 - 1.5 9.3 10.0 1.9 8.9 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 PAP1 PF08601.10 OAJ11286.1 - 1.6 8.4 14.7 1.9 8.2 14.7 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Roughex PF06020.11 OAJ11286.1 - 1.7 7.7 6.7 2.1 7.4 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spc7_N PF15402.6 OAJ11286.1 - 1.7 6.8 12.9 1.8 6.7 12.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PepSY_2 PF13670.6 OAJ11286.1 - 1.8 8.6 6.8 3 7.9 6.8 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Presenilin PF01080.17 OAJ11286.1 - 2 7.1 11.1 2.3 6.9 11.1 1.1 1 0 0 1 1 1 0 Presenilin DUF5521 PF17659.1 OAJ11286.1 - 2.1 6.1 10.6 2.5 5.9 10.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) Tim54 PF11711.8 OAJ11286.1 - 2.3 6.9 9.4 2.7 6.7 9.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Proton_antipo_C PF01010.19 OAJ11286.1 - 2.8 7.5 4.3 3.7 7.1 4.3 1.1 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Zip PF02535.22 OAJ11286.1 - 2.8 7.1 8.8 3.5 6.8 8.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM154 PF15102.6 OAJ11286.1 - 4.1 7.3 8.0 5.3 6.9 8.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.12 OAJ11286.1 - 4.8 5.0 13.0 5.2 4.9 13.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glycophorin_A PF01102.18 OAJ11286.1 - 5.7 7.2 8.6 8.2 6.7 8.6 1.3 1 0 0 1 1 1 0 Glycophorin A EIIBC-GUT_N PF03612.14 OAJ11286.1 - 6.3 6.5 8.0 7.8 6.2 8.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.6 OAJ11286.1 - 9.7 6.6 9.1 14 6.0 9.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SR-25 PF10500.9 OAJ11287.1 - 0.0026 17.4 7.6 0.0026 17.4 7.6 2.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein IQ PF00612.27 OAJ11287.1 - 0.003 17.2 0.5 0.0078 15.9 0.5 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cwf_Cwc_15 PF04889.12 OAJ11287.1 - 0.061 13.1 13.4 1.1 8.9 9.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF755 PF05501.11 OAJ11287.1 - 1.8 8.8 9.2 4.7 7.5 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MRI PF15325.6 OAJ11287.1 - 8.1 7.6 10.8 1.3 10.1 6.2 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection Ank_2 PF12796.7 OAJ11288.1 - 7.6e-09 36.0 0.4 0.043 14.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ11288.1 - 5e-08 33.1 2.4 0.1 12.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ11288.1 - 3.2e-06 27.1 0.5 0.33 11.6 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ11288.1 - 2.6e-05 24.7 0.1 0.79 10.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 OAJ11288.1 - 0.00099 18.9 0.0 0.0033 17.3 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain PEP-utilizers PF00391.23 OAJ11288.1 - 0.026 14.2 0.1 0.08 12.7 0.1 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Ank PF00023.30 OAJ11288.1 - 0.029 14.8 9.3 1.3 9.6 0.1 4.6 5 0 0 5 5 5 0 Ankyrin repeat Spc7 PF08317.11 OAJ11288.1 - 0.28 10.0 1.8 0.47 9.3 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Nop14 PF04147.12 OAJ11289.1 - 2.1 6.5 15.0 3.7 5.6 15.0 1.3 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.10 OAJ11289.1 - 2.4 8.9 12.2 14 6.4 10.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) 60KD_IMP PF02096.20 OAJ11290.1 - 0.055 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein Aldo_ket_red PF00248.21 OAJ11291.1 - 1.8e-40 139.0 0.0 2e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_2 PF04909.14 OAJ11291.1 - 0.045 13.5 0.0 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Amidohydrolase Asn_synthase PF00733.21 OAJ11298.1 - 3.3e-89 300.0 0.1 3.7e-55 188.0 0.0 2.7 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAJ11298.1 - 5.6e-38 129.6 0.0 9.1e-38 128.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAJ11298.1 - 1.6e-29 102.8 0.0 4.4e-29 101.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAJ11298.1 - 7e-05 22.4 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 OAJ11298.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 OAJ11298.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PQ-loop PF04193.14 OAJ11300.1 - 1.8e-35 120.5 6.5 1.1e-17 63.6 1.5 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OAJ11300.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4389 PF14333.6 OAJ11313.1 - 0.088 12.7 2.2 0.11 12.4 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) NDC10_II PF16787.5 OAJ11315.1 - 4.6e-45 154.1 0.0 7.2e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ11315.1 - 0.0012 19.1 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_23 PF13384.6 OAJ11315.1 - 0.04 13.7 2.5 0.12 12.2 0.0 3.2 3 1 1 4 4 4 0 Homeodomain-like domain HTH_28 PF13518.6 OAJ11315.1 - 0.06 13.5 1.0 0.65 10.2 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Dimer_Tnp_hAT PF05699.14 OAJ11316.1 - 4.5e-11 42.4 0.0 7.3e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PHD PF00628.29 OAJ11326.1 - 0.036 14.0 0.3 0.056 13.4 0.3 1.3 1 0 0 1 1 1 0 PHD-finger PKcGMP_CC PF16808.5 OAJ11326.1 - 0.046 13.6 0.4 0.091 12.6 0.4 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CRISPR_Cse2 PF09485.10 OAJ11326.1 - 0.065 13.8 0.1 0.15 12.6 0.1 1.5 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) FAA_hydrolase PF01557.18 OAJ11326.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Pkinase PF00069.25 OAJ11327.1 - 2.6e-46 158.1 0.0 3.7e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11327.1 - 2.9e-23 82.5 0.0 4.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ11327.1 - 4.1e-09 36.2 0.0 7.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Dimer_Tnp_hAT PF05699.14 OAJ11328.1 - 2.2e-17 62.6 1.4 5.1e-17 61.4 1.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ11328.1 - 0.00043 20.6 0.1 0.00089 19.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) NOA36 PF06524.12 OAJ11328.1 - 7.3 5.8 10.7 12 5.1 10.7 1.3 1 0 0 1 1 1 0 NOA36 protein CDO_I PF05995.12 OAJ11329.1 - 0.028 13.8 0.1 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Cysteine dioxygenase type I Vma12 PF11712.8 OAJ11329.1 - 1.1 9.3 3.5 2.5 8.2 2.6 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase UCH PF00443.29 OAJ11338.1 - 6.8e-41 140.5 0.0 1.1e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAJ11338.1 - 1.4e-14 54.5 0.0 3.8e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 OAJ11338.1 - 2.3e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Glutaredoxin PF00462.24 OAJ11339.1 - 1.3e-18 67.0 0.0 3.8e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAJ11339.1 - 2.6e-14 53.0 0.0 4.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ11339.1 - 0.001 19.5 0.0 0.0091 16.4 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ11339.1 - 0.0022 18.3 0.1 0.33 11.3 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.11 OAJ11339.1 - 0.0029 17.5 0.0 0.14 12.1 0.0 2.9 2 2 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF3246 PF11596.8 OAJ11339.1 - 0.029 13.8 1.1 0.044 13.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) GST_N_3 PF13417.6 OAJ11339.1 - 0.075 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HMG_box PF00505.19 OAJ11340.1 - 4.8e-10 39.7 2.8 9.8e-10 38.7 2.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 OAJ11340.1 - 0.0016 17.8 0.2 0.0028 17.0 0.2 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Keratin_B2 PF01500.17 OAJ11340.1 - 0.075 13.0 0.5 0.23 11.4 0.2 2.0 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein AAA_11 PF13086.6 OAJ11350.1 - 0.41 10.4 7.9 0.5 10.1 7.9 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OAJ11350.1 - 0.78 8.4 6.4 0.74 8.5 6.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ11350.1 - 2.1 8.1 15.1 2.4 7.9 15.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 OAJ11359.1 - 5.7e-50 170.1 0.0 8.3e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11359.1 - 6.4e-25 87.9 0.0 2e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ11359.1 - 2.6e-05 23.7 0.0 6.2e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Dimer_Tnp_hAT PF05699.14 OAJ11360.1 - 2.5e-20 72.1 0.1 4.2e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SPAR_C PF11881.8 OAJ11360.1 - 0.016 15.1 1.4 0.025 14.5 1.4 1.2 1 0 0 1 1 1 0 C-terminal domain of SPAR protein DUF3818 PF12825.7 OAJ11360.1 - 0.11 11.5 0.3 0.14 11.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF2457 PF10446.9 OAJ11361.1 - 0.00024 20.4 10.9 0.00024 20.4 10.9 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Mitofilin PF09731.9 OAJ11361.1 - 6.7 5.4 15.5 11 4.7 15.5 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Prp19 PF08606.11 OAJ11371.1 - 9.7e-30 102.4 1.8 2e-29 101.3 1.8 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 OAJ11371.1 - 6.4e-17 61.6 4.4 0.013 16.3 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11371.1 - 4e-14 52.7 0.0 0.035 14.4 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 OAJ11371.1 - 0.0082 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OAJ11371.1 - 0.0093 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 OAJ11371.1 - 0.016 14.6 0.1 0.068 12.5 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3450 PF11932.8 OAJ11371.1 - 0.033 13.5 0.9 0.076 12.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RibD_C PF01872.17 OAJ11372.1 - 3.9e-33 115.0 0.0 7.1e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Sec7 PF01369.20 OAJ11372.1 - 1.2e-31 109.9 0.0 1.7e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain MBF1 PF08523.10 OAJ11373.1 - 2.1e-18 66.5 1.1 4.5e-18 65.5 1.1 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAJ11373.1 - 1e-11 44.7 0.4 1.8e-11 43.9 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OAJ11373.1 - 0.00074 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OAJ11373.1 - 0.0021 18.0 0.2 0.0032 17.4 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Bac_small_YrzI PF09501.10 OAJ11374.1 - 0.37 11.0 0.4 0.65 10.2 0.4 1.3 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Serglycin PF04360.12 OAJ11374.1 - 1.8 8.5 8.5 32 4.4 0.0 2.4 2 0 0 2 2 2 0 Serglycin SNF5 PF04855.12 OAJ11375.1 - 3.9e-58 197.0 1.6 3e-55 187.6 1.6 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 FbpC_C_terminal PF17845.1 OAJ11375.1 - 0.084 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain DUF3224 PF11528.8 OAJ11382.1 - 0.081 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) RT_RNaseH PF17917.1 OAJ11389.1 - 1.1e-08 35.4 0.0 2.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ11389.1 - 0.0038 17.2 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Oxygenase-NA PF09859.9 OAJ11389.1 - 0.027 14.0 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA PAN_4 PF14295.6 OAJ11390.1 - 0.0026 17.6 0.9 0.0051 16.7 0.9 1.4 1 0 0 1 1 1 1 PAN domain GST_N_3 PF13417.6 OAJ11392.1 - 0.00018 21.8 0.0 0.00046 20.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ11392.1 - 0.001 19.0 0.0 0.0071 16.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ11392.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Q_salvage PF10343.9 OAJ11393.1 - 0.051 13.1 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Apolipoprotein PF01442.18 OAJ11394.1 - 0.0015 18.4 14.6 0.0023 17.8 14.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Presenilin PF01080.17 OAJ11394.1 - 0.025 13.4 5.2 0.029 13.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin ISG65-75 PF11727.8 OAJ11394.1 - 0.062 12.5 15.0 0.08 12.2 15.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein V_ATPase_I PF01496.19 OAJ11394.1 - 0.063 11.2 3.8 0.069 11.1 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Plasmodium_Vir PF05795.11 OAJ11394.1 - 0.094 12.1 4.6 0.11 11.9 4.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RRF PF01765.19 OAJ11394.1 - 0.15 12.0 13.3 0.9 9.5 14.4 1.7 2 0 0 2 2 2 0 Ribosome recycling factor DDHD PF02862.17 OAJ11394.1 - 0.17 12.1 2.7 0.21 11.7 2.7 1.3 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.8 OAJ11394.1 - 0.21 11.3 24.4 0.31 10.7 24.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Borrelia_P83 PF05262.11 OAJ11394.1 - 0.27 9.7 18.5 0.36 9.2 18.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3810 PF12725.7 OAJ11394.1 - 0.33 10.2 2.0 0.47 9.8 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Prominin PF05478.11 OAJ11394.1 - 0.36 8.7 5.1 0.44 8.4 5.1 1.0 1 0 0 1 1 1 0 Prominin SLC12 PF03522.15 OAJ11394.1 - 0.36 9.8 9.4 0.44 9.5 9.4 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hormone_1 PF00103.20 OAJ11394.1 - 0.37 10.5 8.4 0.8 9.4 8.4 1.4 1 1 0 1 1 1 0 Somatotropin hormone family GAGA_bind PF06217.12 OAJ11394.1 - 0.42 10.9 10.1 0.52 10.5 10.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family ApoO PF09769.9 OAJ11394.1 - 0.49 10.4 8.3 19 5.2 8.3 2.2 1 1 0 1 1 1 0 Apolipoprotein O SAGA-Tad1 PF12767.7 OAJ11394.1 - 0.58 9.9 7.9 0.72 9.5 7.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TMPIT PF07851.13 OAJ11394.1 - 0.6 9.3 7.3 0.77 8.9 7.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein HSP70 PF00012.20 OAJ11394.1 - 0.89 7.7 14.0 1.1 7.3 14.0 1.0 1 0 0 1 1 1 0 Hsp70 protein RR_TM4-6 PF06459.12 OAJ11394.1 - 1.1 9.0 15.3 1.4 8.6 15.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PA26 PF04636.13 OAJ11394.1 - 1.2 8.0 8.3 1.5 7.7 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ndc1_Nup PF09531.10 OAJ11394.1 - 1.3 7.7 3.9 1.3 7.7 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec62 PF03839.16 OAJ11394.1 - 1.7 8.1 7.2 2.4 7.6 7.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FPN1 PF06963.12 OAJ11394.1 - 3.1 6.3 4.9 5 5.6 4.9 1.4 1 1 0 1 1 1 0 Ferroportin1 (FPN1) CDPS PF16715.5 OAJ11394.1 - 3.4 7.3 9.6 18 4.9 10.0 1.7 1 1 0 1 1 1 0 Cyclodipeptide synthase Neur_chan_memb PF02932.16 OAJ11394.1 - 4.5 7.2 6.7 5.5 7.0 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4337 PF14235.6 OAJ11394.1 - 4.6 7.3 18.7 67 3.5 18.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Membralin PF09746.9 OAJ11394.1 - 5.6 5.9 4.9 6.6 5.7 4.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein XRN_M PF17846.1 OAJ11394.1 - 6 5.7 9.5 7.5 5.4 9.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Atg14 PF10186.9 OAJ11394.1 - 7.8 5.5 13.1 10 5.1 13.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GREB1 PF15782.5 OAJ11394.1 - 9.3 3.2 8.2 11 3.0 8.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PseudoU_synth_1 PF01416.20 OAJ11395.1 - 1.5e-12 47.9 0.0 2e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Zw10 PF06248.13 OAJ11396.1 - 0.00063 18.4 0.8 0.046 12.3 0.0 2.8 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Integrin_alpha2 PF08441.12 OAJ11396.1 - 0.1 11.4 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Integrin alpha Smr PF01713.21 OAJ11396.1 - 0.14 12.6 0.2 19 5.7 0.0 3.2 3 1 0 3 3 3 0 Smr domain Transposase_21 PF02992.14 OAJ11401.1 - 8.5e-16 57.8 0.8 2e-15 56.6 0.0 1.9 3 0 0 3 3 3 1 Transposase family tnp2 Dimer_Tnp_hAT PF05699.14 OAJ11403.1 - 2.3e-12 46.5 0.0 5.6e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4203 PF13886.6 OAJ11415.1 - 1.1e-45 155.8 23.7 1.3e-45 155.5 23.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Trp_oprn_chp PF09534.10 OAJ11415.1 - 0.12 12.2 1.6 0.35 10.7 0.3 2.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Met_10 PF02475.16 OAJ11415.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Pox_P4B PF03292.14 OAJ11415.1 - 0.49 8.6 2.2 0.72 8.0 2.2 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Siah-Interact_N PF09032.11 OAJ11415.1 - 0.74 10.2 9.9 5.1 7.5 0.1 3.4 2 1 0 3 3 3 0 Siah interacting protein, N terminal Pox_A14 PF05767.12 OAJ11415.1 - 0.81 9.9 2.7 2 8.6 2.7 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 CRT10 PF08728.10 OAJ11415.1 - 0.93 7.6 3.4 1.4 6.9 3.4 1.2 1 0 0 1 1 1 0 CRT10 Pkinase PF00069.25 OAJ11416.1 - 2.8e-67 226.9 0.0 3.6e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11416.1 - 1.8e-29 102.9 0.0 3e-29 102.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ11416.1 - 5.3e-05 22.7 0.7 9.8e-05 21.8 0.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ11416.1 - 0.00015 21.2 0.0 0.00029 20.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ11416.1 - 0.00018 20.6 0.5 0.00025 20.1 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ11416.1 - 0.0069 16.3 0.3 1.3 8.8 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ11416.1 - 0.033 13.8 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 RIO1 family AdoHcyase_NAD PF00670.21 OAJ11416.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain RNA_pol_Rpb2_6 PF00562.28 OAJ11417.1 - 6.5e-103 344.8 0.0 1.9e-100 336.7 0.0 2.6 2 1 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ11417.1 - 7.1e-36 123.6 0.0 1.3e-35 122.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAJ11417.1 - 6.5e-27 93.5 0.0 1.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OAJ11417.1 - 9.1e-24 83.2 0.0 1.9e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OAJ11417.1 - 1.3e-19 70.6 0.0 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ11417.1 - 1.2e-16 60.8 0.3 1.8e-14 53.9 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 IMS PF00817.20 OAJ11424.1 - 1.2e-29 103.2 0.0 2.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ11424.1 - 5.5e-06 27.1 0.0 2.3e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ11424.1 - 0.028 14.7 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif MMR_HSR1 PF01926.23 OAJ11425.1 - 1.1e-15 57.7 0.0 1.4e-14 54.1 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ11425.1 - 3.1e-06 26.8 0.0 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ11425.1 - 1.2e-05 25.3 0.2 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase BUD22 PF09073.10 OAJ11425.1 - 0.00034 20.1 17.6 0.00056 19.4 17.6 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.12 OAJ11425.1 - 0.00072 19.1 20.3 0.0012 18.4 20.3 1.3 1 0 0 1 1 1 1 SDA1 AIG1 PF04548.16 OAJ11425.1 - 0.0016 17.8 0.0 0.0055 16.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 OAJ11425.1 - 0.06 13.4 0.6 0.28 11.2 0.5 2.1 2 1 1 3 3 3 0 Dynamin family Mpp10 PF04006.12 OAJ11425.1 - 0.061 11.8 20.9 0.096 11.1 20.9 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 OAJ11425.1 - 0.2 9.9 24.1 0.29 9.4 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ11425.1 - 0.48 8.6 28.9 0.68 8.1 28.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 OAJ11425.1 - 1 8.7 22.3 1.9 7.8 22.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CNDH2_C PF16858.5 OAJ11425.1 - 1.9 8.3 13.1 3.2 7.5 13.1 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AAA PF00004.29 OAJ11426.1 - 1.3e-90 300.7 0.0 5.4e-46 156.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ11426.1 - 3.8e-22 77.8 2.0 1.5e-10 40.7 0.1 2.9 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 OAJ11426.1 - 6.2e-14 52.0 0.0 2.2e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ11426.1 - 1.7e-11 44.8 10.2 0.0017 18.8 0.0 5.5 3 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 OAJ11426.1 - 6e-11 42.8 1.1 0.012 15.9 0.1 5.2 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.14 OAJ11426.1 - 9.3e-11 41.9 0.2 0.00099 19.1 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAJ11426.1 - 1e-10 42.0 0.0 0.00046 20.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 OAJ11426.1 - 2.6e-09 36.8 0.0 4.1e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OAJ11426.1 - 1.4e-08 35.0 0.1 0.0072 16.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 OAJ11426.1 - 4.2e-07 29.6 2.1 0.02 14.3 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAJ11426.1 - 6.2e-07 29.5 0.0 0.042 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAJ11426.1 - 1e-06 29.1 0.0 0.078 13.4 0.0 2.4 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAJ11426.1 - 1.2e-06 28.4 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 OAJ11426.1 - 1.6e-06 28.1 1.0 0.037 14.0 0.1 3.8 3 1 1 4 4 4 2 NACHT domain AAA_28 PF13521.6 OAJ11426.1 - 2.3e-06 27.9 0.0 0.059 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 OAJ11426.1 - 5.6e-06 26.9 0.0 0.098 13.2 0.0 3.0 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 OAJ11426.1 - 9.9e-06 25.6 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAJ11426.1 - 1.3e-05 25.8 0.0 0.27 11.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 OAJ11426.1 - 2.8e-05 24.0 0.0 0.072 12.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAJ11426.1 - 3.7e-05 23.4 2.7 1.1 8.8 0.1 4.3 3 1 1 4 4 4 2 AAA domain Rad17 PF03215.15 OAJ11426.1 - 0.00011 22.2 0.0 0.33 10.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 OAJ11426.1 - 0.00015 21.2 0.1 1.7 7.9 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_17 PF13207.6 OAJ11426.1 - 0.0002 21.8 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 OAJ11426.1 - 0.0002 21.5 0.0 0.051 13.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activat PF00158.26 OAJ11426.1 - 0.00022 21.0 0.1 0.48 10.1 0.0 3.6 4 0 0 4 4 3 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 OAJ11426.1 - 0.00023 20.5 0.1 0.69 9.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 OAJ11426.1 - 0.00031 20.6 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAJ11426.1 - 0.00072 18.8 0.0 0.84 8.8 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain AAA_7 PF12775.7 OAJ11426.1 - 0.0016 18.0 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 OAJ11426.1 - 0.0025 16.9 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 OAJ11426.1 - 0.0025 17.9 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 OAJ11426.1 - 0.003 16.8 0.0 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 OAJ11426.1 - 0.0039 17.0 3.5 1.2 8.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 OAJ11426.1 - 0.0042 16.8 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 OAJ11426.1 - 0.0056 15.6 0.0 0.78 8.6 0.0 2.4 2 0 0 2 2 2 1 AFG1-like ATPase Vps4_C PF09336.10 OAJ11426.1 - 0.0089 16.0 0.0 5.1 7.2 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 OAJ11426.1 - 0.009 15.9 0.0 1.8 8.4 0.0 2.7 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea PhoH PF02562.16 OAJ11426.1 - 0.0093 15.4 0.3 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 OAJ11426.1 - 0.016 14.7 0.0 17 4.7 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein SKI PF01202.22 OAJ11426.1 - 0.02 15.0 0.0 6.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Lzipper-MIP1 PF14389.6 OAJ11426.1 - 0.032 14.5 0.5 0.13 12.5 0.2 2.2 2 0 0 2 2 1 0 Leucine-zipper of ternary complex factor MIP1 NTPase_1 PF03266.15 OAJ11426.1 - 0.07 13.0 0.1 8.1 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 OAJ11426.1 - 0.072 12.8 0.0 9.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 OAJ11426.1 - 0.11 12.8 1.2 13 6.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 OAJ11426.1 - 0.13 12.3 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Hydin_ADK PF17213.3 OAJ11426.1 - 0.64 10.3 8.8 3.8 7.8 0.0 3.3 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain DUF4741 PF15897.5 OAJ11427.1 - 0.053 13.3 2.5 0.12 12.2 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) RT_RNaseH PF17917.1 OAJ11434.1 - 1.2e-11 44.8 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11434.1 - 4.5e-08 33.3 0.0 3.5e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ11434.1 - 1.2e-06 28.5 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp PF00026.23 OAJ11444.1 - 4.8e-43 147.8 0.0 1.1e-42 146.6 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ11444.1 - 4.4e-07 30.3 0.3 0.0033 17.7 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Tissue_fac PF01108.17 OAJ11444.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Tissue factor Ras PF00071.22 OAJ11445.1 - 2.3e-48 163.9 0.0 2.8e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ11445.1 - 1.7e-22 79.9 0.0 2.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ11445.1 - 1.4e-05 24.7 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ11445.1 - 0.015 14.9 0.0 0.046 13.3 0.0 1.7 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 OAJ11446.1 - 6.2e-11 42.7 0.5 0.0043 17.9 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11446.1 - 0.075 13.3 0.0 63 4.0 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ATP-sulfurylase PF01747.17 OAJ11447.1 - 9.6e-88 293.2 0.1 1.5e-87 292.6 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAJ11447.1 - 1.7e-54 184.0 0.0 2.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAJ11447.1 - 3.8e-50 169.7 0.0 6.2e-50 169.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain SHR3_chaperone PF08229.11 OAJ11448.1 - 2.9e-39 134.0 0.0 4.5e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 DUF1772 PF08592.11 OAJ11448.1 - 0.054 13.8 0.5 0.31 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1771 PF08590.10 OAJ11449.1 - 3.3e-16 59.4 7.9 5.6e-16 58.7 7.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ11449.1 - 6.2e-10 39.3 0.3 1.2e-09 38.3 0.3 1.5 1 0 0 1 1 1 1 Smr domain Ta0938 PF11494.8 OAJ11449.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Ta0938 Pkinase PF00069.25 OAJ11456.1 - 1.6e-41 142.5 0.0 2.5e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11456.1 - 2.7e-18 66.2 0.0 4.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ11456.1 - 3.8e-06 26.4 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Dimer_Tnp_hAT PF05699.14 OAJ11457.1 - 1e-12 47.6 0.1 2.3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RNase_H2_suC PF08615.11 OAJ11457.1 - 1.5 9.0 4.9 19 5.4 2.4 2.8 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RCC1 PF00415.18 OAJ11467.1 - 6.8e-06 26.6 0.1 4.1e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat SOBP PF15279.6 OAJ11467.1 - 4 8.0 7.2 4.5 7.8 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Nup96 PF12110.8 OAJ11468.1 - 2.1e-88 296.2 0.0 2.9e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAJ11468.1 - 3.5e-50 170.0 0.0 5.8e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAJ11468.1 - 2.5e-28 98.7 337.3 4.9e-08 33.7 34.0 12.1 4 2 10 15 15 15 12 Nucleoporin FG repeat region Fe-ADH PF00465.19 OAJ11469.1 - 1.9e-93 313.2 0.0 2.5e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ11469.1 - 3.2e-11 43.4 0.0 3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 OAJ11469.1 - 0.087 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein NifU_N PF01592.16 OAJ11470.1 - 1.2e-54 183.9 0.1 1.9e-54 183.2 0.1 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain Proteasome PF00227.26 OAJ11471.1 - 3e-60 203.0 0.0 5e-60 202.3 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ11471.1 - 2e-09 36.9 0.0 7.6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SH3_9 PF14604.6 OAJ11472.1 - 0.00044 20.1 0.1 0.052 13.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAJ11472.1 - 0.0022 17.6 0.0 0.0051 16.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain NMT_C PF02799.15 OAJ11482.1 - 6.5e-73 244.7 0.0 1.3e-72 243.7 0.0 1.5 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAJ11482.1 - 7.4e-72 240.4 0.0 1.1e-71 239.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAJ11482.1 - 0.0063 16.6 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ11482.1 - 0.032 14.5 0.0 0.078 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NotI PF12183.8 OAJ11482.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease NotI Acetyltransf_10 PF13673.7 OAJ11482.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fib_alpha PF08702.10 OAJ11489.1 - 4.9e-05 23.5 3.7 7.2e-05 23.0 3.7 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 OAJ11489.1 - 7.4e-05 21.8 18.0 9.5e-05 21.4 18.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein UPF0242 PF06785.11 OAJ11489.1 - 0.00028 21.0 21.0 0.00036 20.7 13.7 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 OAJ11489.1 - 0.00058 20.3 16.4 0.00058 20.3 16.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 OAJ11489.1 - 0.0024 17.9 1.3 0.0024 17.9 1.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAJ11489.1 - 0.0035 16.6 8.4 0.0043 16.3 8.4 1.3 1 1 0 1 1 1 1 TMPIT-like protein ISG65-75 PF11727.8 OAJ11489.1 - 0.0066 15.7 9.7 0.0066 15.7 9.7 1.7 1 1 1 2 2 2 1 Invariant surface glycoprotein Bacillus_HBL PF05791.11 OAJ11489.1 - 0.009 15.9 2.9 0.013 15.3 2.9 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Filament PF00038.21 OAJ11489.1 - 0.011 15.3 20.9 0.046 13.3 10.4 2.6 1 1 2 3 3 3 0 Intermediate filament protein Atg14 PF10186.9 OAJ11489.1 - 0.012 14.7 14.4 0.018 14.2 14.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 OAJ11489.1 - 0.027 14.7 21.2 0.075 13.3 20.2 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 OAJ11489.1 - 0.028 12.0 15.5 0.033 11.7 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-K PF11802.8 OAJ11489.1 - 0.052 13.1 10.3 0.067 12.8 10.3 1.1 1 0 0 1 1 1 0 Centromere-associated protein K FapA PF03961.13 OAJ11489.1 - 0.06 11.9 8.3 0.068 11.8 8.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KxDL PF10241.9 OAJ11489.1 - 0.064 13.5 7.9 0.27 11.5 1.6 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein MscS_porin PF12795.7 OAJ11489.1 - 0.067 12.7 14.6 0.11 12.1 11.8 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain CREPT PF16566.5 OAJ11489.1 - 0.075 13.2 13.0 0.15 12.2 1.4 3.0 1 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour HAUS-augmin3 PF14932.6 OAJ11489.1 - 0.11 12.1 15.9 0.027 14.0 12.6 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Leu_zip PF15294.6 OAJ11489.1 - 0.12 11.9 15.0 0.12 11.9 13.7 1.6 1 1 1 2 2 2 0 Leucine zipper DUF3552 PF12072.8 OAJ11489.1 - 0.13 11.7 28.0 0.054 12.9 15.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATG16 PF08614.11 OAJ11489.1 - 0.17 12.1 26.5 0.043 14.0 8.0 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 OAJ11489.1 - 0.28 11.0 21.6 0.59 9.9 21.6 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 OAJ11489.1 - 0.29 11.2 26.3 0.72 9.9 9.8 2.9 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 OAJ11489.1 - 0.3 11.7 12.1 0.18 12.5 7.7 2.2 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 OAJ11489.1 - 0.31 11.1 24.1 0.099 12.7 19.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 OAJ11489.1 - 0.38 11.1 23.2 0.23 11.7 6.2 2.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 OAJ11489.1 - 0.39 10.0 19.8 0.92 8.8 17.7 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 OAJ11489.1 - 0.4 10.5 16.0 3.7 7.3 4.9 2.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4407 PF14362.6 OAJ11489.1 - 0.42 9.9 15.6 0.58 9.5 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 OAJ11489.1 - 0.42 10.4 29.6 0.11 12.3 24.9 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 OAJ11489.1 - 0.5 10.7 9.6 1.3 9.3 2.8 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF730 PF05325.11 OAJ11489.1 - 0.54 10.3 5.9 3.1 7.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Uds1 PF15456.6 OAJ11489.1 - 0.73 10.0 18.1 0.56 10.4 2.7 2.7 1 1 2 3 3 3 0 Up-regulated During Septation DUF1043 PF06295.12 OAJ11489.1 - 0.86 9.6 9.2 2.9 7.9 9.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Lebercilin PF15619.6 OAJ11489.1 - 0.96 9.1 23.5 0.04 13.6 15.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 OAJ11489.1 - 1.1 9.3 23.6 7.5 6.6 23.8 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 OAJ11489.1 - 1.5 9.1 18.4 0.82 9.9 4.9 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OAJ11489.1 - 1.8 8.4 17.4 1.6 8.6 5.2 2.6 1 1 2 3 3 3 0 Septum formation initiator AAA_13 PF13166.6 OAJ11489.1 - 1.8 7.1 14.9 3.1 6.3 14.8 1.4 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 OAJ11489.1 - 2.1 7.8 11.9 3.6 7.1 11.9 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 OAJ11489.1 - 2.2 9.0 12.8 1.1 9.9 3.8 2.8 1 1 2 3 3 3 0 SlyX CRR7 PF12095.8 OAJ11489.1 - 2.2 8.8 5.5 12 6.5 0.9 2.7 1 1 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF3450 PF11932.8 OAJ11489.1 - 2.2 7.5 15.5 0.66 9.2 8.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) PCRF PF03462.18 OAJ11489.1 - 2.4 8.0 16.0 0.84 9.5 4.7 2.0 1 1 1 2 2 2 0 PCRF domain CC2-LZ PF16516.5 OAJ11489.1 - 2.5 8.5 19.1 0.5 10.8 3.1 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Synaptobrevin PF00957.21 OAJ11489.1 - 2.7 7.8 4.4 1.3 8.9 0.4 2.1 2 1 0 2 2 2 0 Synaptobrevin GrpE PF01025.19 OAJ11489.1 - 3.7 7.2 19.1 4.8 6.8 6.4 2.4 1 1 1 2 2 2 0 GrpE DHR10 PF18595.1 OAJ11489.1 - 3.9 7.5 27.4 0.45 10.6 16.7 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Occludin_ELL PF07303.13 OAJ11489.1 - 4.4 8.1 9.8 3.6 8.4 6.4 2.2 1 1 1 2 2 2 0 Occludin homology domain HemX PF04375.14 OAJ11489.1 - 4.8 6.4 12.2 3.8 6.7 10.4 1.7 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase zf-C4H2 PF10146.9 OAJ11489.1 - 4.9 7.4 11.5 6 7.1 11.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF16 PF01519.16 OAJ11489.1 - 5 7.7 13.4 5.1 7.6 1.7 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5339 PF17274.2 OAJ11489.1 - 6 7.8 8.5 1.4 9.8 1.4 2.9 1 1 1 3 3 3 0 Family of unknown function (DUF5339) FlaC_arch PF05377.11 OAJ11489.1 - 6.3 7.3 8.4 8.2 6.9 4.0 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 OAJ11489.1 - 6.3 7.2 15.4 1.7 9.1 11.4 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) NYD-SP28_assoc PF14775.6 OAJ11489.1 - 6.5 6.9 12.5 0.23 11.6 1.8 3.3 3 1 1 4 4 3 0 Sperm tail C-terminal domain Ax_dynein_light PF10211.9 OAJ11489.1 - 7.4 6.5 20.8 1.2 9.1 10.5 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain eIF3_N PF09440.10 OAJ11489.1 - 8.1 6.9 9.6 4.5 7.7 5.0 2.2 1 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain YkyA PF10368.9 OAJ11489.1 - 9.6 5.8 20.1 11 5.7 18.9 1.8 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Dimer_Tnp_hAT PF05699.14 OAJ11490.1 - 4.8e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nucleoporin_FG PF13634.6 OAJ11497.1 - 6e-06 27.0 53.6 0.0078 17.0 52.6 2.8 1 1 0 1 1 1 1 Nucleoporin FG repeat region Abhydrolase_3 PF07859.13 OAJ11497.1 - 0.0039 17.1 0.4 0.0047 16.8 0.4 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Nup_retrotrp_bd PF10599.9 OAJ11497.1 - 3 8.6 20.0 0.69 10.6 5.1 2.2 1 1 1 2 2 2 0 Retro-transposon transporting motif eIF-3_zeta PF05091.12 OAJ11497.1 - 4.5 6.1 12.8 5.3 5.9 12.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apc15p PF05841.11 OAJ11497.1 - 5.7 7.7 18.3 0.48 11.2 9.2 2.1 2 0 0 2 2 2 0 Apc15p protein Ndc1_Nup PF09531.10 OAJ11497.1 - 7 5.2 19.8 8.2 5.0 19.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA_anti-codon PF01336.25 OAJ11498.1 - 0.0009 19.2 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Serglycin PF04360.12 OAJ11498.1 - 0.016 15.1 4.0 0.55 10.2 1.2 2.5 2 0 0 2 2 2 0 Serglycin RMI2 PF16100.5 OAJ11498.1 - 0.058 13.2 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 Cwf_Cwc_15 PF04889.12 OAJ11498.1 - 0.55 9.9 14.7 0.68 9.6 4.0 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CoA_binding_2 PF13380.6 OAJ11499.1 - 4.8e-32 110.9 0.1 5.5e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OAJ11499.1 - 0.00056 20.5 0.0 0.00084 20.0 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain La PF05383.17 OAJ11500.1 - 3.2e-17 62.3 0.0 5.5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 La domain PAP2 PF01569.21 OAJ11501.1 - 1.1e-27 96.4 3.4 1.1e-27 96.4 3.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 OAJ11501.1 - 0.013 15.2 9.1 0.016 14.9 7.1 2.2 1 1 1 2 2 2 0 PAP2 superfamily NAD_kinase PF01513.21 OAJ11502.1 - 2.7e-73 246.7 0.0 9.7e-72 241.6 0.0 2.7 1 1 0 1 1 1 1 ATP-NAD kinase DNA_pol_phi PF04931.13 OAJ11502.1 - 3.3 5.7 31.5 7.6 4.5 31.5 1.5 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ11502.1 - 8.5 4.4 31.3 0.0063 14.8 17.0 2.4 3 0 0 3 3 3 0 Nop14-like family XPG_I PF00867.18 OAJ11509.1 - 1.2e-06 28.8 0.0 8.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 XPG I-region RelB_transactiv PF16181.5 OAJ11509.1 - 0.0041 17.4 1.4 0.037 14.3 0.9 2.5 2 0 0 2 2 2 1 RelB transactivation domain 5_3_exonuc PF01367.20 OAJ11509.1 - 0.0087 16.6 0.1 0.041 14.5 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DDE_Tnp_1_2 PF13586.6 OAJ11509.1 - 0.12 12.8 0.6 0.37 11.2 0.6 1.8 1 0 0 1 1 1 0 Transposase DDE domain XPG_N PF00752.17 OAJ11509.1 - 0.18 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain SNF2_N PF00176.23 OAJ11510.1 - 1.5e-59 201.5 0.1 2.6e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ11510.1 - 1.2e-12 48.2 0.0 2.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 OAJ11510.1 - 2.6e-05 24.1 1.0 6.1e-05 22.9 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ11510.1 - 0.0005 19.9 1.0 0.0005 19.9 1.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ11510.1 - 0.00078 19.4 0.5 0.002 18.1 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ11510.1 - 0.0024 17.7 2.8 0.009 15.9 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ11510.1 - 0.0031 17.8 1.6 0.0084 16.4 1.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAJ11510.1 - 0.0036 17.1 0.9 0.0094 15.8 0.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAJ11510.1 - 0.059 13.2 9.8 0.018 14.8 5.1 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 OAJ11510.1 - 0.31 11.3 1.2 0.92 9.8 1.2 1.8 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ResIII PF04851.15 OAJ11510.1 - 4.8 7.1 11.5 0.47 10.4 0.0 3.5 3 2 0 3 3 3 0 Type III restriction enzyme, res subunit MFS_1 PF07690.16 OAJ11511.1 - 2.5e-37 128.6 39.4 1.2e-31 109.9 18.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2484 PF10658.9 OAJ11511.1 - 1.4 9.3 7.0 0.41 11.0 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) DUF2070 PF09843.9 OAJ11511.1 - 9.8 4.3 7.6 22 3.2 7.6 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mpp10 PF04006.12 OAJ11519.1 - 1.6e-105 353.9 62.7 1.7e-98 330.7 44.9 2.0 1 1 1 2 2 2 2 Mpp10 protein DENN PF02141.21 OAJ11520.1 - 4.5e-22 78.9 0.0 7.3e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Spc7 PF08317.11 OAJ11520.1 - 0.059 12.2 14.2 0.0063 15.4 9.4 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Branch PF02485.21 OAJ11520.1 - 0.17 11.4 0.2 2.5 7.5 0.2 2.2 2 0 0 2 2 2 0 Core-2/I-Branching enzyme APG6_N PF17675.1 OAJ11520.1 - 0.24 11.9 13.6 0.16 12.5 10.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4201 PF13870.6 OAJ11520.1 - 0.39 10.4 11.4 0.06 13.1 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AAA_13 PF13166.6 OAJ11520.1 - 0.69 8.5 9.0 0.35 9.5 2.8 2.1 2 0 0 2 2 2 0 AAA domain HMMR_N PF15905.5 OAJ11520.1 - 0.75 9.2 12.1 0.17 11.4 8.1 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF724 PF05266.14 OAJ11520.1 - 1.4 8.7 14.2 0.24 11.2 9.6 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) OmpH PF03938.14 OAJ11520.1 - 2.1 8.7 6.7 0.52 10.6 2.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 OAJ11520.1 - 2.4 7.2 15.7 2.9 6.9 0.2 2.8 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 OAJ11520.1 - 2.4 7.6 16.4 0.1 12.1 7.7 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 OAJ11520.1 - 3.1 7.1 17.0 0.82 9.0 11.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HSCB_C PF07743.13 OAJ11520.1 - 3.2 8.3 10.6 0.087 13.3 1.5 2.8 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Cluap1 PF10234.9 OAJ11520.1 - 4.3 6.6 13.4 0.35 10.2 6.4 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 CENP-F_leu_zip PF10473.9 OAJ11520.1 - 4.3 7.3 19.4 1.1 9.3 3.0 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 OAJ11520.1 - 5.5 7.0 6.3 15 5.6 0.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SOGA PF11365.8 OAJ11520.1 - 8.6 7.6 13.1 2.1 9.5 8.4 2.6 2 0 0 2 2 1 0 Protein SOGA Peptidase_C1_2 PF03051.15 OAJ11522.1 - 1.2e-115 386.8 0.0 1.8e-114 382.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAJ11522.1 - 5.8e-07 29.8 0.2 0.0013 18.9 0.3 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DUF4634 PF15465.6 OAJ11522.1 - 0.067 13.5 0.1 0.9 9.8 0.0 2.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4634) Gar1 PF04410.14 OAJ11528.1 - 4.2e-33 114.3 0.0 5.3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AA_permease PF00324.21 OAJ11529.1 - 1.2e-63 215.4 31.4 1.6e-63 215.0 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAJ11529.1 - 4.7e-13 49.0 24.6 2.9e-09 36.5 0.0 5.0 5 1 1 6 6 6 3 Solute carrier family 12 bZIP_1 PF00170.21 OAJ11538.1 - 0.0019 18.3 7.7 0.0049 16.9 7.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor COG4 PF08318.12 OAJ11538.1 - 0.0032 16.6 3.4 0.0065 15.6 3.4 1.5 1 0 0 1 1 1 1 COG4 transport protein TFIIA PF03153.13 OAJ11538.1 - 0.0041 17.2 35.4 0.0075 16.3 23.2 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 OAJ11538.1 - 0.0068 15.4 27.7 0.014 14.4 27.7 1.6 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF812 PF05667.11 OAJ11538.1 - 0.11 11.4 22.9 0.12 11.2 16.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TERB2 PF15101.6 OAJ11538.1 - 0.28 11.2 9.3 0.91 9.5 9.3 1.9 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex26 PF07163.12 OAJ11538.1 - 0.57 9.4 7.5 1.4 8.2 7.5 1.6 1 0 0 1 1 1 0 Pex26 protein Spt20 PF12090.8 OAJ11538.1 - 1.2 8.7 28.5 0.084 12.5 22.6 2.1 2 0 0 2 2 2 0 Spt20 family Rpp20 PF12328.8 OAJ11538.1 - 4.4 7.3 7.3 14 5.7 7.3 1.8 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P WD40 PF00400.32 OAJ11539.1 - 3.5e-35 119.4 13.2 9.8e-05 23.1 0.2 10.6 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11539.1 - 5.8e-14 52.2 0.5 0.00015 22.0 0.0 6.5 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ11539.1 - 0.00021 20.3 2.5 2.2 7.1 0.0 4.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ11539.1 - 0.00077 18.2 0.0 0.0022 16.7 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Frtz PF11768.8 OAJ11539.1 - 0.0016 16.8 0.0 0.0036 15.7 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz eIF2A PF08662.11 OAJ11539.1 - 0.0037 17.2 0.2 0.052 13.4 0.1 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 OAJ11539.1 - 0.0048 16.3 0.2 4.5 6.5 0.0 3.5 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Phage_sheath_1 PF04984.14 OAJ11539.1 - 0.026 14.4 0.1 0.085 12.7 0.1 1.9 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain WD40_like PF17005.5 OAJ11539.1 - 0.13 11.6 0.0 29 3.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 OAJ11539.1 - 0.14 12.7 22.1 0.38 11.3 0.0 6.6 7 1 0 7 7 7 0 PQQ-like domain Utp8 PF10395.9 OAJ11539.1 - 0.24 9.9 0.0 1.1 7.7 0.0 1.8 2 0 0 2 2 2 0 Utp8 family PQQ PF01011.21 OAJ11539.1 - 0.48 10.4 9.3 3 7.9 0.1 5.2 6 0 0 6 6 6 0 PQQ enzyme repeat Abhydrolase_6 PF12697.7 OAJ11540.1 - 3.2e-05 24.7 0.1 4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ11540.1 - 0.00077 19.2 0.1 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 OAJ11540.1 - 0.00079 19.3 0.1 0.0042 17.0 0.1 1.9 1 1 1 2 2 2 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 OAJ11540.1 - 0.0031 17.1 0.0 0.032 13.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 OAJ11540.1 - 0.0069 16.1 0.3 0.032 13.9 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ11540.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.11 OAJ11540.1 - 0.073 12.4 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 OAJ11540.1 - 0.19 10.9 0.1 0.24 10.5 0.1 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PBP1_TM PF14812.6 OAJ11541.1 - 0.0042 17.4 3.6 8.1 6.9 6.2 2.4 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop53 PF07767.11 OAJ11541.1 - 0.012 15.0 2.8 0.02 14.3 2.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DnaJ PF00226.31 OAJ11542.1 - 3.5e-19 68.7 0.1 6.2e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.20 OAJ11542.1 - 2.4e-08 34.1 0.0 4.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 DHH family adh_short PF00106.25 OAJ11543.1 - 7.8e-24 84.2 0.0 1.8e-23 83.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11543.1 - 1.2e-18 67.6 0.0 9.7e-18 64.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11543.1 - 3.6e-06 27.0 0.1 1.1e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.17 OAJ11543.1 - 0.00028 21.4 0.3 0.013 16.1 0.1 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 OAJ11543.1 - 0.0012 18.1 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ11543.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAJ11543.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 OAJ11543.1 - 0.11 11.5 0.2 0.15 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NmrA PF05368.13 OAJ11543.1 - 0.39 10.2 1.6 0.63 9.5 0.0 2.1 3 0 0 3 3 3 0 NmrA-like family RsfS PF02410.15 OAJ11550.1 - 0.007 16.8 0.1 0.017 15.5 0.1 1.8 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation HTH_23 PF13384.6 OAJ11550.1 - 0.031 14.1 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Ribosomal_L22 PF00237.19 OAJ11551.1 - 1.5e-24 86.2 0.7 1.5e-24 86.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SPT_ssu-like PF11779.8 OAJ11552.1 - 2.4e-05 23.8 0.3 3.6e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Jiraiya PF15038.6 OAJ11552.1 - 0.0095 15.4 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Jiraiya Neurensin PF14927.6 OAJ11552.1 - 0.06 13.1 0.1 0.085 12.6 0.1 1.4 1 1 0 1 1 1 0 Neurensin TALPID3 PF15324.6 OAJ11552.1 - 0.23 9.1 2.2 0.27 8.9 2.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Abhydrolase_1 PF00561.20 OAJ11554.1 - 1.1e-17 64.6 0.0 1.5e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ11554.1 - 1.4e-16 61.8 1.6 1.7e-16 61.5 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ11554.1 - 1.2e-09 37.8 0.0 4.2e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 OAJ11554.1 - 2e-06 27.8 0.2 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Ndr PF03096.14 OAJ11554.1 - 2.7e-06 26.3 0.0 1.3e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 OAJ11554.1 - 0.033 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAJ11554.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Aldo_ket_red PF00248.21 OAJ11555.1 - 9.9e-71 238.3 0.0 1.2e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.23 OAJ11556.1 - 5.3e-15 55.9 0.0 9.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ11556.1 - 6.9e-08 33.0 0.0 5.2e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ11556.1 - 0.025 14.4 0.0 0.06 13.2 0.0 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DUF3446 PF11928.8 OAJ11556.1 - 4.4 7.7 16.2 11 6.4 0.9 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Zn_clus PF00172.18 OAJ11557.1 - 3.3e-08 33.5 10.2 5.8e-08 32.7 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LapA_dom PF06305.11 OAJ11567.1 - 0.087 12.7 0.1 0.087 12.7 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 2OG-FeII_Oxy_3 PF13640.6 OAJ11568.1 - 2.6e-08 34.6 0.4 8.1e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAJ11568.1 - 0.074 13.7 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAP PF07174.11 OAJ11569.1 - 0.0021 17.6 4.7 0.0021 17.6 4.7 2.2 2 0 0 2 2 2 1 Fibronectin-attachment protein (FAP) S1FA PF04689.13 OAJ11571.1 - 0.0079 16.3 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 DNA binding protein S1FA GTP_EFTU PF00009.27 OAJ11580.1 - 1.8e-44 151.6 0.0 3.6e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ11580.1 - 1.3e-32 112.5 0.3 1.3e-31 109.2 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ11580.1 - 9.6e-09 35.5 1.7 1.2e-08 35.3 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ11580.1 - 0.0036 17.4 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hamartin PF04388.12 OAJ11580.1 - 1.1 7.8 13.9 1.6 7.3 13.9 1.2 1 0 0 1 1 1 0 Hamartin protein Mitofilin PF09731.9 OAJ11580.1 - 1.9 7.2 29.7 2.9 6.6 29.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RhoGAP PF00620.27 OAJ11581.1 - 1.3e-37 129.0 0.3 3e-37 127.8 0.1 1.7 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAJ11581.1 - 9e-23 80.3 35.3 7.6e-10 38.9 6.3 5.0 5 0 0 5 5 5 4 LIM domain DUF2722 PF10846.8 OAJ11581.1 - 0.018 14.0 0.0 0.018 14.0 0.0 5.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2722) PACT_coil_coil PF10495.9 OAJ11582.1 - 2.8e-14 53.5 0.6 2.8e-14 53.5 0.6 4.4 5 2 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Seryl_tRNA_N PF02403.22 OAJ11582.1 - 0.011 15.9 12.8 0.011 15.9 12.8 6.0 2 2 4 6 6 6 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 OAJ11582.1 - 0.051 13.8 45.0 0.3 11.3 0.2 7.2 7 0 0 7 7 7 0 Homeobox associated leucine zipper KLRAQ PF10205.9 OAJ11582.1 - 9.9 6.5 67.2 0.35 11.1 8.1 6.9 2 1 4 6 6 6 0 Predicted coiled-coil domain-containing protein RRM_1 PF00076.22 OAJ11583.1 - 1.6e-29 101.5 0.2 2.9e-12 46.2 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ11583.1 - 1.7e-05 24.8 0.0 0.0048 17.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 OAJ11583.1 - 0.0011 18.8 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_9 PF18444.1 OAJ11583.1 - 0.16 11.8 0.0 0.5 10.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif Mito_carr PF00153.27 OAJ11592.1 - 2.7e-35 120.2 0.1 3e-23 81.6 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF572 PF04502.13 OAJ11594.1 - 1.9e-82 277.6 0.7 2.2e-82 277.3 0.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 OAJ11594.1 - 0.31 11.1 2.6 8.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain adh_short PF00106.25 OAJ11595.1 - 1.5e-30 106.1 1.2 2.2e-30 105.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11595.1 - 1.8e-23 83.3 0.2 2.3e-23 83.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11595.1 - 2.4e-07 30.9 0.2 4e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ11595.1 - 2.3e-06 27.7 0.8 2.5e-06 27.5 0.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ11595.1 - 0.00091 18.8 0.1 0.0014 18.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ11595.1 - 0.0037 16.7 0.0 0.0093 15.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAJ11595.1 - 0.0068 16.0 1.0 0.0098 15.5 1.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 OAJ11595.1 - 0.1 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Mt_ATP-synt_B PF05405.14 OAJ11596.1 - 0.06 13.0 0.2 0.074 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GPAT_N PF14829.6 OAJ11596.1 - 0.11 12.5 0.4 0.14 12.1 0.4 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Cmc1 PF08583.10 OAJ11597.1 - 4.2e-14 52.3 1.9 5.1e-14 52.0 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NIP_1 PF08995.10 OAJ11597.1 - 0.081 13.3 0.3 0.1 13.0 0.3 1.1 1 0 0 1 1 1 0 Necrosis inducing protein-1 Fungal_trans PF04082.18 OAJ11598.1 - 9.4e-08 31.4 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ11598.1 - 2.7e-05 24.2 14.3 4.2e-05 23.6 14.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1348 PF07080.11 OAJ11605.1 - 6.1e-59 197.6 8.0 7e-59 197.4 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAJ11605.1 - 3e-05 24.6 0.1 4.2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 OAJ11606.1 - 4e-38 131.3 0.2 5.8e-38 130.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ11606.1 - 4.4e-32 111.1 0.0 5.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ11606.1 - 6e-06 26.3 0.0 9.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAJ11606.1 - 0.0034 16.7 0.0 0.0085 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OAJ11606.1 - 0.0096 16.3 0.3 0.026 15.0 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAJ11606.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ11606.1 - 0.033 14.2 0.1 0.066 13.3 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ11606.1 - 0.061 13.6 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NYN PF01936.18 OAJ11607.1 - 1.2e-22 81.0 0.0 2.8e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 NYN domain Pex14_N PF04695.13 OAJ11607.1 - 4.7 7.8 26.0 1.7 9.3 1.3 4.4 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HVSL PF09749.9 OAJ11608.1 - 1.1e-32 113.5 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein tRNA-synt_1 PF00133.22 OAJ11609.1 - 2.1e-44 151.8 0.0 5e-36 124.1 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAJ11609.1 - 1.8e-13 50.0 0.0 9.8e-08 31.1 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAJ11609.1 - 4.1e-11 43.1 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAJ11609.1 - 5.1e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 OAJ11609.1 - 0.04 13.4 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Cation_ATPase PF13246.6 OAJ11617.1 - 0.0054 16.8 0.0 0.0079 16.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Herpes_IR6 PF06307.12 OAJ11617.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus IR6 protein FAM196 PF15265.6 OAJ11618.1 - 0.005 16.4 12.5 0.0054 16.3 12.5 1.0 1 0 0 1 1 1 1 FAM196 family UPF0506 PF11703.8 OAJ11618.1 - 0.017 15.5 9.1 0.84 10.1 0.2 2.2 2 0 0 2 2 2 0 UPF0506 FGF-BP1 PF06473.12 OAJ11618.1 - 0.071 12.9 8.7 0.088 12.6 8.7 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) LEAP-2 PF07359.11 OAJ11618.1 - 0.22 11.4 6.1 0.51 10.2 0.8 2.2 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Apt1 PF10351.9 OAJ11618.1 - 4.8 5.9 11.1 4.6 6.0 11.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PIGA PF08288.12 OAJ11619.1 - 8.3e-41 138.5 0.1 1.7e-40 137.5 0.1 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAJ11619.1 - 6.5e-28 97.9 1.8 1.2e-27 97.0 1.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ11619.1 - 8.2e-24 84.1 0.0 1.3e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ11619.1 - 1.4e-21 77.3 0.0 2.9e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ11619.1 - 7.5e-13 49.2 0.3 1.9e-12 47.9 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAJ11619.1 - 4.5e-07 30.2 0.0 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OAJ11619.1 - 7.1e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like GFA PF04828.14 OAJ11621.1 - 4.5e-09 36.5 0.0 7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 OAJ11621.1 - 0.097 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Nudix N-terminal DDE_Tnp_4 PF13359.6 OAJ11631.1 - 3.9e-05 23.4 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ11631.1 - 0.041 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein DDE_3 PF13358.6 OAJ11633.1 - 7.6e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ11633.1 - 3.8e-06 27.4 0.4 4.2e-05 24.1 0.1 2.7 2 1 1 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ11633.1 - 5.7e-06 25.9 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAJ11633.1 - 9.4e-06 25.8 0.1 0.00062 20.0 0.0 2.4 2 0 0 2 2 2 1 Transposase Arg_repressor PF01316.21 OAJ11633.1 - 0.00022 20.9 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DUF2293 PF10056.9 OAJ11633.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) HTH_ABP1_N PF18107.1 OAJ11633.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain RSRP PF17069.5 OAJ11634.1 - 5.5 6.5 12.8 8.9 5.8 12.8 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Myb_DNA-bind_3 PF12776.7 OAJ11635.1 - 8.4e-18 65.2 0.1 1.7e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ11635.1 - 0.0091 16.4 0.4 0.026 14.9 0.4 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain NAM-associated PF14303.6 OAJ11635.1 - 0.037 14.7 11.0 1.1 9.9 1.7 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain TSC22 PF01166.18 OAJ11652.1 - 0.039 14.3 1.0 0.12 12.7 0.8 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family TRIQK PF15168.6 OAJ11652.1 - 1.2 9.1 5.5 0.48 10.4 1.1 2.3 2 1 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF3395 PF11875.8 OAJ11652.1 - 4 7.3 8.7 0.3 11.0 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) DivIC PF04977.15 OAJ11652.1 - 9.2 6.1 9.3 24 4.8 0.1 2.8 2 1 1 3 3 3 0 Septum formation initiator FAM196 PF15265.6 OAJ11654.1 - 0.022 14.3 0.7 0.027 14.0 0.7 1.1 1 0 0 1 1 1 0 FAM196 family TPR_MLP1_2 PF07926.12 OAJ11655.1 - 0.0025 17.9 5.3 0.0033 17.5 5.3 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PP2C_C PF07830.13 OAJ11655.1 - 0.03 14.8 0.3 0.037 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Cortex-I_coil PF09304.10 OAJ11655.1 - 0.078 13.2 3.6 0.089 13.0 3.6 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF2205 PF10224.9 OAJ11655.1 - 0.11 12.5 1.9 0.26 11.3 0.5 2.0 1 1 1 2 2 2 0 Short coiled-coil protein FLILHELTA PF10306.9 OAJ11663.1 - 2.4e-14 53.5 0.0 4.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 OAJ11663.1 - 0.007 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribonuclease_P PF00825.18 OAJ11664.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease P Mt_ATP-synt_B PF05405.14 OAJ11665.1 - 1.8e-47 161.0 5.9 2.2e-47 160.7 5.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.8 OAJ11665.1 - 0.0016 18.5 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Cauli_DNA-bind PF03310.13 OAJ11665.1 - 0.19 11.8 1.4 0.31 11.1 0.4 1.7 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein IBR PF01485.21 OAJ11666.1 - 1.5e-06 28.3 26.6 0.00013 22.2 5.1 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain COX5A PF02284.16 OAJ11667.1 - 3.5e-42 142.6 0.4 4.5e-42 142.3 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3523 PF12037.8 OAJ11667.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Coa1 PF08695.10 OAJ11668.1 - 5.9e-32 109.9 0.0 8.3e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RICTOR_N PF14664.6 OAJ11669.1 - 1.9e-67 227.9 0.0 1.8e-66 224.6 0.0 2.7 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 OAJ11669.1 - 2.7e-31 107.4 0.7 2.8e-28 97.7 0.5 4.5 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OAJ11669.1 - 9e-29 100.0 0.0 7e-28 97.2 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OAJ11669.1 - 8.5e-28 96.4 0.3 5.7e-26 90.5 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAJ11669.1 - 6.8e-07 29.3 1.3 6.8e-07 29.3 1.3 2.5 2 0 0 2 2 2 1 Hr1 repeat HEAT PF02985.22 OAJ11669.1 - 0.15 12.4 1.6 1 9.8 0.2 3.1 3 0 0 3 3 3 0 HEAT repeat Spt20 PF12090.8 OAJ11669.1 - 0.53 9.9 10.0 0.95 9.0 10.0 1.3 1 0 0 1 1 1 0 Spt20 family GET2 PF08690.10 OAJ11669.1 - 4.5 6.9 9.5 5.2 6.7 6.6 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 Suf PF05843.14 OAJ11669.1 - 4.7 7.1 8.0 8.9 6.2 8.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zn_clus PF00172.18 OAJ11677.1 - 0.0003 20.9 12.0 0.00049 20.2 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAJ11677.1 - 5.1 6.6 22.9 2.7 7.5 9.9 3.1 3 0 0 3 3 3 0 Spt20 family SNRNP27 PF08648.12 OAJ11678.1 - 5.8e-26 90.3 0.9 5.8e-26 90.3 0.9 1.8 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins DUF1708 PF08101.11 OAJ11679.1 - 4.9e-26 91.9 0.7 1.6e-23 83.6 0.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ11679.1 - 0.00027 20.8 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain HAMP_N3 PF18575.1 OAJ11679.1 - 0.036 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Pkinase PF00069.25 OAJ11680.1 - 1.1e-62 211.8 0.0 1.4e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11680.1 - 3.1e-34 118.4 0.0 4.5e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ11680.1 - 5.8e-07 28.6 0.0 9.3e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ11680.1 - 0.00022 20.6 0.0 0.00055 19.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ11680.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ11680.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEC-1_C PF04626.13 OAJ11680.1 - 0.25 11.8 3.5 1.3 9.4 3.5 2.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Seadorna_VP7 PF07387.11 OAJ11680.1 - 0.25 10.3 0.0 0.37 9.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ribonuclease_3 PF00636.26 OAJ11688.1 - 1.8e-14 54.2 0.0 4.4e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ11688.1 - 0.00092 19.4 0.1 0.016 15.4 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like DUF1840 PF08895.11 OAJ11688.1 - 0.06 13.7 0.6 2.1 8.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) COX6A PF02046.15 OAJ11689.1 - 7.2e-32 110.2 0.0 8.4e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Abhydrolase_1 PF00561.20 OAJ11690.1 - 1e-36 126.9 0.1 2.7e-19 69.8 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Git3 PF11710.8 OAJ11691.1 - 2.6e-08 33.9 9.5 6.5e-08 32.6 9.5 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAJ11691.1 - 2.3e-07 30.4 0.0 3.1e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAJ11691.1 - 0.071 13.2 0.1 0.071 13.2 0.1 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term YqzE PF14038.6 OAJ11691.1 - 0.079 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 YqzE-like protein RVT_2 PF07727.14 OAJ11702.1 - 0.0092 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc5 PF03221.16 OAJ11703.1 - 5.8e-08 32.7 0.1 1.5e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 OAJ11703.1 - 0.025 14.7 0.3 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_1 PF03184.19 OAJ11704.1 - 1.5e-21 76.9 0.2 1.7e-21 76.7 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.14 OAJ11707.1 - 4.4e-28 98.5 0.0 5e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 OAJ11707.1 - 0.075 12.7 0.0 0.092 12.4 0.0 1.3 1 1 0 1 1 1 0 Chlororespiratory reduction 6 gag_pre-integrs PF13976.6 OAJ11708.1 - 1.4e-06 28.0 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 OAJ11708.1 - 5.3e-05 23.4 0.0 0.00043 20.5 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain Glyco_hydro_45 PF02015.16 OAJ11716.1 - 3.8e-25 89.1 1.9 4.8e-25 88.7 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Lipase_3 PF01764.25 OAJ11718.1 - 2.9e-19 69.4 0.1 4.3e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ11718.1 - 5.2e-05 22.6 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ11718.1 - 0.0039 17.8 0.3 0.0076 16.9 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family RHH_8 PF17723.1 OAJ11718.1 - 0.19 11.9 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family PWI PF01480.17 OAJ11719.1 - 2.7e-26 91.7 0.0 4e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.25 OAJ11720.1 - 6.3e-63 212.6 0.0 8.8e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11720.1 - 2e-27 96.1 0.0 1e-26 93.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ11720.1 - 5.6e-06 27.0 0.4 5.3e-05 23.8 0.4 2.7 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 OAJ11720.1 - 0.0051 16.5 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAJ11720.1 - 0.023 14.0 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 OAJ11721.1 - 2.3e-11 43.9 14.6 1.1e-08 35.5 0.5 5.0 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.17 OAJ11721.1 - 0.0053 16.8 0.2 0.99 9.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat T3SSipB PF16535.5 OAJ11721.1 - 0.018 15.5 0.7 0.045 14.2 0.7 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF2587 PF10759.9 OAJ11721.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Iso_dh PF00180.20 OAJ11729.1 - 2.7e-77 260.3 0.0 3.8e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribonuclease_T2 PF00445.18 OAJ11730.1 - 3.6e-35 121.8 0.0 4.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1077 PF06417.12 OAJ11731.1 - 2e-47 160.1 1.1 2.5e-47 159.7 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF5589 PF17672.1 OAJ11731.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5589) PTH2 PF01981.16 OAJ11732.1 - 7.5e-08 32.7 0.0 1.2e-07 32.1 0.0 1.4 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Acyl-CoA_dh_N PF02771.16 OAJ11733.1 - 3e-28 98.7 0.0 5.6e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ11733.1 - 5.6e-24 85.0 0.0 1e-23 84.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ11733.1 - 1.3e-22 79.8 0.0 2.9e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ11733.1 - 0.00012 22.4 0.3 0.00012 22.4 0.3 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DNA_pol_phi PF04931.13 OAJ11734.1 - 0.00018 19.8 27.8 0.00029 19.1 27.2 1.6 2 0 0 2 2 2 1 DNA polymerase phi Astro_capsid_p PF12226.8 OAJ11734.1 - 0.23 10.6 18.4 0.42 9.7 18.4 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Mpp10 PF04006.12 OAJ11734.1 - 0.29 9.5 24.7 0.021 13.3 19.4 1.7 2 0 0 2 2 2 0 Mpp10 protein Nop14 PF04147.12 OAJ11734.1 - 0.36 9.0 33.9 0.0041 15.4 26.5 1.4 2 0 0 2 2 2 0 Nop14-like family DUF2890 PF11081.8 OAJ11734.1 - 4.1 7.5 10.0 7.4 6.7 9.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) IFT57 PF10498.9 OAJ11734.1 - 6.8 5.6 12.0 12 4.8 12.0 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RRN3 PF05327.11 OAJ11734.1 - 7.3 5.0 20.0 12 4.3 20.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAJ11734.1 - 9 6.1 22.9 0.82 9.5 17.3 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Acyl-CoA_dh_N PF02771.16 OAJ11735.1 - 2.6e-19 70.0 0.0 4.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain GFO_IDH_MocA PF01408.22 OAJ11737.1 - 1.5e-17 64.5 0.2 2.3e-17 63.9 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold COesterase PF00135.28 OAJ11738.1 - 9.5e-75 252.4 0.1 4.6e-66 223.7 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ11738.1 - 4e-06 26.8 0.0 1.8e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_Mycoplasma PF07672.13 OAJ11738.1 - 0.066 12.5 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter rve PF00665.26 OAJ11744.1 - 7.5e-14 51.9 0.0 1.2e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAJ11744.1 - 1.7e-08 34.3 0.1 3.3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 OAJ11744.1 - 0.0072 16.1 0.2 0.075 12.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Nup84_Nup100 PF04121.13 OAJ11755.1 - 1e-126 423.9 0.0 1.7e-126 423.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Aida_N PF08910.10 OAJ11755.1 - 0.081 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Aida N-terminus Clat_adaptor_s PF01217.20 OAJ11756.1 - 2.7e-19 69.5 0.0 4e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Dendrin PF15498.6 OAJ11756.1 - 0.096 11.4 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin ATG7_N PF16420.5 OAJ11757.1 - 4e-84 282.8 0.0 6.1e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAJ11757.1 - 1.1e-46 159.2 0.0 1.5e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAJ11757.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 OAJ11758.1 - 4.5e-17 62.2 0.0 1e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 ThiF family Ribosomal_L11_N PF03946.14 OAJ11759.1 - 2.5e-24 84.9 0.7 4.5e-24 84.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ11759.1 - 2.8e-21 75.8 0.4 4.3e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TFIIB PF00382.19 OAJ11760.1 - 9.3e-39 131.3 2.8 7.2e-22 77.2 0.9 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAJ11760.1 - 1.2e-12 47.2 1.8 2e-12 46.4 1.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 OAJ11760.1 - 0.011 15.8 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain RB_B PF01857.20 OAJ11760.1 - 0.023 14.8 0.1 0.054 13.5 0.1 1.6 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 OAJ11760.1 - 0.11 12.3 0.5 0.24 11.1 0.1 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain HARE-HTH PF05066.13 OAJ11760.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain UQ_con PF00179.26 OAJ11767.1 - 6.8e-43 145.7 0.0 7.6e-43 145.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ11767.1 - 0.0033 17.1 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ11767.1 - 0.13 12.6 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF3128 PF11326.8 OAJ11768.1 - 0.0012 19.1 0.7 0.0019 18.6 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 OAJ11768.1 - 0.0065 16.7 1.7 0.07 13.4 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 OAJ11768.1 - 0.011 15.7 2.2 0.016 15.2 2.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 OAJ11768.1 - 0.012 15.8 1.4 0.019 15.2 1.4 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4692 PF15763.5 OAJ11768.1 - 0.03 14.8 0.6 0.038 14.5 0.6 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Pet191_N PF10203.9 OAJ11768.1 - 0.032 14.5 0.8 0.051 13.9 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 OAJ11768.1 - 1.1 9.5 7.8 4.9 7.4 8.1 1.9 1 1 1 2 2 2 0 CHCH domain WD40 PF00400.32 OAJ11769.1 - 1e-38 130.6 18.3 2.2e-08 34.6 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 OAJ11769.1 - 3.9e-30 104.7 0.0 8.1e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 OAJ11769.1 - 2.7e-07 30.8 0.0 0.23 11.8 0.0 4.5 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAJ11769.1 - 0.0029 17.5 0.1 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 OAJ11769.1 - 0.21 10.5 0.0 24 3.8 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallophos PF00149.28 OAJ11772.1 - 1.8e-36 126.6 0.1 3.3e-36 125.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ11772.1 - 5.6e-17 61.9 0.0 1e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIIA PF03153.13 OAJ11772.1 - 0.1 12.6 16.8 0.14 12.2 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 OAJ11772.1 - 0.31 10.4 3.9 0.58 9.5 3.8 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF2973 PF11189.8 OAJ11772.1 - 0.42 10.8 2.1 1 9.5 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Spt20 PF12090.8 OAJ11772.1 - 8.4 5.9 18.6 17 4.9 18.6 1.5 1 0 0 1 1 1 0 Spt20 family HTH_24 PF13412.6 OAJ11773.1 - 0.069 12.7 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Pkinase PF00069.25 OAJ11774.1 - 5.6e-69 232.4 0.0 7.9e-69 231.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11774.1 - 6.6e-34 117.4 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 OAJ11774.1 - 0.0047 16.6 0.0 0.058 13.1 0.0 2.3 2 0 0 2 2 2 1 Fungal kinase associated-1 domain APH PF01636.23 OAJ11774.1 - 0.005 16.8 0.0 0.024 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ11774.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ11774.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OAJ11774.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 OAJ11774.1 - 0.03 13.9 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TFB6 PF17110.5 OAJ11785.1 - 0.51 10.1 3.8 0.9 9.3 3.8 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH COesterase PF00135.28 OAJ11786.1 - 5.2e-07 28.9 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ11786.1 - 0.00032 20.6 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ11786.1 - 0.0019 17.7 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ11786.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lactamase_B_2 PF12706.7 OAJ11787.1 - 2.2e-07 30.6 0.0 2e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ11787.1 - 4.6e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ11787.1 - 0.00017 21.7 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 OAJ11787.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Glyco_hydro_47 PF01532.20 OAJ11788.1 - 1.3e-150 502.3 0.0 1.6e-150 502.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PQ-loop PF04193.14 OAJ11789.1 - 8.4e-30 102.3 3.6 1.9e-16 59.5 0.7 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAJ11789.1 - 0.15 12.9 1.9 2.7 8.8 0.2 2.4 2 1 1 3 3 3 0 ER lumen protein retaining receptor Asp PF00026.23 OAJ11790.1 - 8e-114 380.3 0.2 1.1e-113 379.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ11790.1 - 3.8e-17 63.1 1.4 4.3e-15 56.4 1.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ11790.1 - 2.8e-05 24.0 0.0 0.00074 19.3 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ11790.1 - 0.00062 20.4 0.0 0.63 10.7 0.0 3.3 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11790.1 - 0.0061 17.1 0.0 2.9 8.5 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease BDHCT_assoc PF16204.5 OAJ11790.1 - 0.07 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein SurA_N_3 PF13624.6 OAJ11790.1 - 0.14 11.9 0.2 17 5.2 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain KASH PF10541.9 OAJ11794.1 - 1.7 9.0 6.4 3.4 8.0 1.3 3.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain HhH-GPD PF00730.25 OAJ11795.1 - 1.7e-09 38.1 0.0 3.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Rib_5-P_isom_A PF06026.14 OAJ11796.1 - 4.7e-60 202.1 0.0 7.8e-60 201.4 0.0 1.4 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OAJ11796.1 - 0.035 14.0 0.0 0.85 9.5 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Cellulase PF00150.18 OAJ11797.1 - 7e-13 48.6 0.1 2.3e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Yip1 PF04893.17 OAJ11797.1 - 0.069 12.9 0.4 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 Yip1 domain Nucleoporin_FG PF13634.6 OAJ11799.1 - 1.9e-08 35.0 154.6 0.31 11.9 34.1 6.9 1 1 3 4 4 4 2 Nucleoporin FG repeat region NupH_GANP PF16768.5 OAJ11799.1 - 1.4 8.5 144.9 0.21 11.3 9.0 5.6 1 1 5 6 6 6 0 Nucleoporin homology of Germinal-centre associated nuclear protein ANAPC1 PF12859.7 OAJ11800.1 - 1.7 9.2 7.6 5.1 7.7 7.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 FancD2 PF14631.6 OAJ11800.1 - 5.5 4.2 5.1 6.7 4.0 5.1 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 OAJ11800.1 - 7.5 6.3 8.5 9.7 5.9 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAJ11800.1 - 8.4 5.0 8.4 9.8 4.8 8.4 1.3 1 0 0 1 1 1 0 Presenilin DUF5572 PF17733.1 OAJ11806.1 - 9.6e-18 63.8 0.8 9.6e-18 63.8 0.8 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5572) DUF4381 PF14316.6 OAJ11806.1 - 0.05 13.9 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.32 OAJ11807.1 - 1.6e-23 82.5 12.9 5.3e-06 27.1 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ11807.1 - 5.7e-10 39.4 0.1 0.0075 16.5 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ11807.1 - 0.0013 17.7 0.4 0.28 10.1 0.1 3.1 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAJ11807.1 - 0.041 13.7 0.1 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAJ11807.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PD40 PF07676.12 OAJ11807.1 - 0.16 12.0 0.7 44 4.2 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WDCP PF15390.6 OAJ11807.1 - 0.2 10.0 0.7 0.28 9.5 0.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family LRR_4 PF12799.7 OAJ11808.1 - 2.8e-11 43.4 31.0 2.7 8.5 0.3 12.8 11 3 3 14 14 14 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ11808.1 - 1.1e-06 28.2 38.1 11 6.4 0.1 15.2 18 0 0 18 18 18 4 Leucine Rich repeat LRR_8 PF13855.6 OAJ11808.1 - 2.6e-06 27.1 45.2 3.2 7.6 0.1 14.3 14 6 3 17 17 17 7 Leucine rich repeat LRR_1 PF00560.33 OAJ11808.1 - 1.4e-05 24.9 19.9 50 5.0 0.0 13.9 18 0 0 18 18 18 0 Leucine Rich Repeat NifU PF01106.17 OAJ11808.1 - 3.3e-05 24.0 2.5 4.6 7.5 0.0 5.0 4 0 0 4 4 4 2 NifU-like domain VWA PF00092.28 OAJ11808.1 - 0.0033 17.7 0.0 0.024 14.9 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain ACT PF01842.25 OAJ11808.1 - 0.0073 16.1 0.0 68 3.4 0.0 4.5 3 0 0 3 3 3 0 ACT domain DUF257 PF03192.13 OAJ11808.1 - 0.068 13.0 0.0 27 4.5 0.0 3.0 3 0 0 3 3 3 0 Pyrococcus protein of unknown function, DUF257 VWA_2 PF13519.6 OAJ11808.1 - 0.16 12.6 1.5 0.6 10.8 0.0 3.0 4 0 0 4 4 4 0 von Willebrand factor type A domain EphA2_TM PF14575.6 OAJ11809.1 - 0.15 13.0 4.9 1.7 9.6 0.0 3.2 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Tetraspanin PF00335.20 OAJ11809.1 - 0.15 11.7 16.0 0.025 14.3 10.9 1.9 1 1 1 2 2 2 0 Tetraspanin family TMEM51 PF15345.6 OAJ11809.1 - 0.19 11.5 1.0 4 7.2 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Tri3 PF07428.11 OAJ11810.1 - 3e-06 26.4 0.0 1.9e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 DUF2934 PF11154.8 OAJ11810.1 - 0.11 12.2 0.2 0.27 10.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) AATase PF07247.12 OAJ11810.1 - 0.31 9.5 0.1 1.4 7.4 0.1 1.8 1 1 0 1 1 1 0 Alcohol acetyltransferase GTP_EFTU PF00009.27 OAJ11825.1 - 8e-51 172.3 0.0 1.3e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAJ11825.1 - 1.3e-37 128.2 0.2 2.4e-37 127.3 0.2 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAJ11825.1 - 6.6e-14 51.7 0.1 3.3e-13 49.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ11825.1 - 1.5e-06 28.5 0.2 2.9e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ11825.1 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 OAJ11825.1 - 0.00075 19.5 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OAJ11825.1 - 0.0041 16.6 0.0 0.0082 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 OAJ11825.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain PH PF00169.29 OAJ11835.1 - 3e-05 24.5 0.0 6.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAJ11835.1 - 0.017 15.5 0.0 0.054 13.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain 4HBT_3 PF13622.6 OAJ11836.1 - 8.5e-29 101.5 0.8 1.3e-28 100.9 0.8 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ11836.1 - 0.00057 19.7 0.0 0.00087 19.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA thioesterase HSP70 PF00012.20 OAJ11837.1 - 2.9e-262 871.2 11.9 3.4e-262 871.0 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ11837.1 - 1.9e-16 59.8 1.3 8.4e-14 51.1 0.3 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 OAJ11837.1 - 0.0028 17.4 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 OAJ11837.1 - 0.0036 17.7 7.3 0.38 11.2 0.2 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Seryl_tRNA_N PF02403.22 OAJ11837.1 - 0.035 14.3 8.5 0.11 12.7 8.1 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Transcrip_reg PF01709.20 OAJ11837.1 - 0.065 12.6 7.8 0.026 14.0 3.7 2.0 2 0 0 2 2 2 0 Transcriptional regulator 4HBT_3 PF13622.6 OAJ11838.1 - 7.8e-31 108.2 0.4 2.9e-30 106.3 0.4 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ11838.1 - 2.1e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA thioesterase PAF-AH_p_II PF03403.13 OAJ11839.1 - 3.2e-37 127.9 0.0 3.1e-20 72.0 0.0 3.1 2 2 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 OAJ11839.1 - 0.044 12.7 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 OAJ11839.1 - 0.073 12.3 0.2 2.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Sugar_tr PF00083.24 OAJ11840.1 - 3.4e-57 194.3 13.1 3.9e-57 194.1 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TrkA_TMD PF18613.1 OAJ11840.1 - 0.44 10.0 2.8 7.4 6.1 0.4 2.5 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain DUF3611 PF12263.8 OAJ11840.1 - 1.8 8.5 8.3 8.6 6.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) Integrase_H2C2 PF17921.1 OAJ11846.1 - 3.2e-15 56.0 0.0 5.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ11846.1 - 1.2e-14 54.2 0.0 5e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11846.1 - 8.4e-11 42.1 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ11846.1 - 9.6e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ11846.1 - 0.015 15.6 0.0 0.073 13.4 0.0 2.2 2 1 0 2 2 2 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ11846.1 - 0.035 14.3 0.8 0.092 13.0 0.0 2.1 3 0 0 3 3 3 0 H2C2 zinc finger Asp_protease_2 PF13650.6 OAJ11847.1 - 0.00032 21.3 0.0 0.00089 19.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11847.1 - 0.0041 17.6 0.0 0.0093 16.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Thioredoxin_8 PF13905.6 OAJ11848.1 - 6e-10 39.3 0.0 2.2e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OAJ11848.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ11848.1 - 0.043 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family BAG PF02179.16 OAJ11849.1 - 2.3e-15 56.8 0.0 6.9e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAJ11849.1 - 1.7e-08 34.1 0.0 3.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 OAJ11849.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Casc1_N PF15927.5 OAJ11849.1 - 1.8 8.2 4.6 2.5 7.8 2.6 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Retrotrans_gag PF03732.17 OAJ11850.1 - 0.026 14.8 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein GATase_2 PF00310.21 OAJ11851.1 - 1.5e-178 593.9 0.0 2e-178 593.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAJ11851.1 - 8.9e-156 518.6 0.0 1.9e-155 517.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAJ11851.1 - 7.4e-111 370.1 0.0 2.1e-110 368.6 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAJ11851.1 - 7.7e-87 289.8 2.6 1.4e-86 289.0 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAJ11851.1 - 2.9e-29 102.2 0.1 2.7e-28 99.1 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAJ11851.1 - 7.8e-22 77.2 0.1 2.2e-21 75.7 0.0 1.8 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAJ11851.1 - 5.8e-09 36.1 0.0 2.3e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAJ11851.1 - 1.8e-07 30.8 0.0 3.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAJ11851.1 - 3.7e-07 30.6 4.5 0.0001 22.7 0.4 4.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ11851.1 - 7.8e-06 25.4 3.0 0.0017 17.7 0.1 4.2 4 1 1 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ11851.1 - 1e-05 25.1 0.3 1e-05 25.1 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 OAJ11851.1 - 1.9e-05 24.4 1.5 0.0014 18.3 0.5 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ11851.1 - 4.9e-05 22.6 3.3 0.00044 19.5 0.3 3.1 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 OAJ11851.1 - 8.1e-05 21.5 0.2 8.1e-05 21.5 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ11851.1 - 0.00013 21.3 0.1 0.35 10.1 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ11851.1 - 0.00088 18.6 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAJ11851.1 - 0.0015 17.8 0.2 0.0015 17.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAJ11851.1 - 0.0039 16.3 0.7 0.025 13.7 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAJ11851.1 - 0.0045 16.1 0.2 0.73 8.8 0.1 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein FMN_dh PF01070.18 OAJ11851.1 - 0.0083 15.2 2.4 0.021 13.9 1.8 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ11851.1 - 0.011 15.2 0.1 0.053 12.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.24 OAJ11851.1 - 0.012 15.4 2.3 6.2 6.6 0.1 3.4 1 1 2 3 3 3 0 DJ-1/PfpI family NAD_binding_7 PF13241.6 OAJ11851.1 - 0.049 14.1 3.0 1.4 9.4 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 OAJ11851.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 OAJ11851.1 - 0.066 13.3 1.9 16 5.5 0.0 3.3 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATase_6 PF13522.6 OAJ11851.1 - 0.079 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain 3HCDH_N PF02737.18 OAJ11851.1 - 0.73 9.7 4.4 0.32 10.9 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spo7 PF03907.13 OAJ11859.1 - 1e-27 97.1 0.0 1.4e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Spo7-like protein FAD_binding_4 PF01565.23 OAJ11860.1 - 1.1e-24 86.8 1.6 2.2e-24 85.8 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ11860.1 - 3.2e-06 27.1 0.1 6.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1815 PF08844.10 OAJ11860.1 - 0.087 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) CFEM PF05730.11 OAJ11862.1 - 0.02 15.0 4.9 0.026 14.6 4.3 1.5 1 1 0 1 1 1 0 CFEM domain ATF7IP_BD PF16788.5 OAJ11862.1 - 0.063 13.4 2.9 0.099 12.7 2.9 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain SWIRM-assoc_2 PF16496.5 OAJ11862.1 - 0.081 11.8 3.5 0.1 11.4 3.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Tim54 PF11711.8 OAJ11862.1 - 0.18 10.5 2.2 0.24 10.1 2.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Chorion_2 PF03964.15 OAJ11862.1 - 4.9 8.0 10.0 4.8 8.1 8.1 1.8 1 1 1 2 2 2 0 Chorion family 2 TonB_N PF16031.5 OAJ11862.1 - 8.9 6.8 12.2 5.9 7.4 10.3 1.6 1 1 1 2 2 2 0 TonB polyproline region GPI-anchored PF10342.9 OAJ11863.1 - 6.1e-06 26.9 1.3 6.1e-06 26.9 1.3 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LIP PF03583.14 OAJ11864.1 - 0.0058 16.0 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase GTP_EFTU PF00009.27 OAJ11865.1 - 5.7e-44 150.0 0.0 9.9e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAJ11865.1 - 1e-31 110.0 5.4 1.9e-31 109.2 5.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAJ11865.1 - 3e-24 85.1 0.0 7.5e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ11865.1 - 3.3e-19 68.7 0.0 9e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 OAJ11865.1 - 6.2e-07 29.5 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAJ11865.1 - 6.5e-07 29.6 0.2 1.6e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 OAJ11865.1 - 0.00011 22.2 0.1 0.00026 21.0 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 OAJ11865.1 - 0.0026 17.4 0.0 0.0082 15.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAJ11865.1 - 0.024 14.8 0.0 0.11 12.7 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ11865.1 - 0.049 13.1 0.1 0.16 11.4 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAJ11865.1 - 0.14 11.7 0.4 2 7.9 0.4 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B DDE_Tnp_4 PF13359.6 OAJ11872.1 - 2e-21 76.3 0.0 2.6e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ11872.1 - 3.2e-05 23.7 0.0 7.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ11872.1 - 0.0038 16.8 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 OAJ11872.1 - 0.03 14.7 0.1 0.06 13.7 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain YL1 PF05764.13 OAJ11874.1 - 2.2e-06 28.0 0.9 3.2e-06 27.4 0.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein CENP-B_dimeris PF09026.10 OAJ11874.1 - 0.00031 21.1 7.9 0.00051 20.4 7.9 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF2457 PF10446.9 OAJ11874.1 - 0.002 17.4 5.6 0.002 17.4 5.6 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 OAJ11874.1 - 0.0046 15.3 3.5 0.0056 15.0 3.5 1.1 1 0 0 1 1 1 1 CDC45-like protein TIMELESS_C PF05029.13 OAJ11874.1 - 0.0048 16.1 5.4 0.0059 15.8 5.4 1.1 1 0 0 1 1 1 1 Timeless protein C terminal region Nop14 PF04147.12 OAJ11874.1 - 0.018 13.3 7.5 0.022 13.0 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ11874.1 - 0.049 13.1 11.0 0.065 12.7 11.0 1.1 1 0 0 1 1 1 0 SDA1 PTPRCAP PF15713.5 OAJ11874.1 - 0.14 12.5 10.3 0.22 11.8 10.3 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BSP_II PF05432.11 OAJ11874.1 - 0.16 11.7 9.5 0.23 11.1 9.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 OAJ11874.1 - 0.36 10.1 12.3 0.55 9.5 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 OAJ11874.1 - 0.62 8.5 2.5 0.68 8.4 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 OAJ11874.1 - 0.82 9.3 3.8 1.5 8.4 3.8 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 OAJ11874.1 - 1.1 9.3 5.9 1.7 8.6 5.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal GREB1 PF15782.5 OAJ11874.1 - 1.1 6.2 5.5 1.4 6.0 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PBP1_TM PF14812.6 OAJ11874.1 - 1.2 9.5 19.5 1.8 9.0 18.2 2.1 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 OAJ11874.1 - 1.5 8.6 7.2 2.2 8.1 7.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TLP-20 PF06088.11 OAJ11874.1 - 1.6 8.6 5.1 3.1 7.7 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ANAPC15 PF15243.6 OAJ11874.1 - 1.8 9.0 15.1 3.7 8.0 15.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CAF1A PF12253.8 OAJ11874.1 - 9.1 6.5 15.6 4.8 7.4 13.0 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A MULE PF10551.9 OAJ11875.1 - 0.036 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 MULE transposase domain Pes-10 PF07149.11 OAJ11875.1 - 0.56 9.2 4.2 0.88 8.6 4.2 1.2 1 0 0 1 1 1 0 Pes-10 zf-BED PF02892.15 OAJ11880.1 - 0.032 14.3 2.4 0.073 13.1 2.4 1.6 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.14 OAJ11881.1 - 6.9e-14 51.4 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 OAJ11882.1 - 5.6e-16 58.7 0.0 1.1e-15 57.8 0.0 1.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11882.1 - 0.00037 19.8 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.6 OAJ11882.1 - 0.042 14.0 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 RTC4-like domain RVT_1 PF00078.27 OAJ11883.1 - 9.2e-22 77.6 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11883.1 - 1.5e-19 69.8 0.0 1.6e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11883.1 - 5.1e-15 55.7 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ11883.1 - 2.2e-14 53.6 0.0 9.8e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11883.1 - 6.7e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ11883.1 - 0.00097 19.7 0.1 0.0038 17.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11883.1 - 0.038 14.5 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ11883.1 - 0.076 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PSK_trans_fac PF07704.11 OAJ11884.1 - 0.025 15.3 1.2 0.37 11.6 0.0 2.5 2 0 0 2 2 2 0 Rv0623-like transcription factor Retrotrans_gag PF03732.17 OAJ11884.1 - 0.063 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Sugar_tr PF00083.24 OAJ11890.1 - 1.1e-112 377.2 10.3 1.7e-112 376.6 10.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ11890.1 - 4.6e-23 81.7 39.2 5.1e-21 75.0 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 OAJ11890.1 - 0.063 12.0 0.0 0.29 9.8 0.0 1.9 2 0 0 2 2 2 0 Reduced folate carrier RT_RNaseH_2 PF17919.1 OAJ11891.1 - 3.6e-20 71.9 0.0 7e-12 45.3 0.0 3.4 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11891.1 - 8.2e-16 58.2 0.0 1.2e-10 41.6 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11891.1 - 1.7e-14 53.6 0.0 5.6e-14 52.0 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11891.1 - 6.6e-13 48.9 0.0 6e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ11891.1 - 6.8e-11 42.1 0.0 4.5e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ11891.1 - 8.8e-06 26.3 0.0 0.00031 21.3 0.0 2.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11891.1 - 0.00088 19.8 0.0 0.0074 16.8 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease bZIP_2 PF07716.15 OAJ11898.1 - 2e-09 37.4 13.0 2e-09 37.4 13.0 3.5 2 1 0 2 2 1 1 Basic region leucine zipper PAT1 PF09770.9 OAJ11898.1 - 0.00013 20.4 40.3 0.00021 19.8 40.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 OAJ11898.1 - 0.00028 20.1 9.8 0.00055 19.1 9.8 1.4 1 0 0 1 1 1 1 CLN3 protein Macoilin PF09726.9 OAJ11898.1 - 0.00037 19.2 22.6 0.0008 18.1 14.5 2.6 2 0 0 2 2 2 2 Macoilin family Zip PF02535.22 OAJ11898.1 - 0.024 13.9 9.4 0.049 12.8 9.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter YabA PF06156.13 OAJ11898.1 - 0.14 12.8 22.4 0.87 10.3 0.0 2.6 2 0 0 2 2 2 0 Initiation control protein YabA GREB1 PF15782.5 OAJ11898.1 - 2.4 5.2 28.4 3.5 4.6 28.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FHIPEP PF00771.20 OAJ11898.1 - 5.9 5.2 17.6 11 4.4 17.6 1.3 1 0 0 1 1 1 0 FHIPEP family Glyco_transf_41 PF13844.6 OAJ11898.1 - 8.1 4.8 15.0 12 4.2 15.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 CobT PF06213.12 OAJ11898.1 - 8.4 5.7 45.0 0.11 11.9 36.8 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SID-1_RNA_chan PF13965.6 OAJ11898.1 - 9.6 4.5 14.7 14 3.9 14.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NAT PF04768.13 OAJ11899.1 - 1.7e-27 96.2 0.0 3.4e-18 65.9 0.0 2.4 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase CdiA_C_tRNase PF18664.1 OAJ11899.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain MFS_1 PF07690.16 OAJ11900.1 - 1.1e-39 136.3 43.3 5.9e-39 134.0 43.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ11900.1 - 2.9e-15 55.7 12.5 4.7e-15 55.0 12.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ11900.1 - 3.1e-13 49.4 12.5 3.1e-13 49.4 12.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ11901.1 - 1.2e-17 63.9 30.6 1.2e-17 63.9 30.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAJ11901.1 - 1.5e-14 54.0 7.0 1.5e-14 54.0 7.0 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 ABC2_membrane_5 PF13346.6 OAJ11901.1 - 0.01 15.4 4.9 0.01 15.4 4.9 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein MFS_1_like PF12832.7 OAJ11901.1 - 0.27 10.0 13.1 0.016 14.1 6.6 2.1 1 1 0 2 2 2 0 MFS_1 like family Serglycin PF04360.12 OAJ11902.1 - 0.76 9.7 10.6 1.3 8.9 10.6 1.3 1 0 0 1 1 1 0 Serglycin CpXC PF14353.6 OAJ11904.1 - 0.0018 18.3 0.3 0.043 13.9 0.1 2.1 2 0 0 2 2 2 1 CpXC protein Zn_Tnp_IS1 PF03811.13 OAJ11904.1 - 0.023 14.4 0.3 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 InsA N-terminal domain DUF2387 PF09526.10 OAJ11904.1 - 0.051 13.7 2.1 2 8.6 0.1 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 OAJ11904.1 - 0.066 13.2 0.2 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 OAJ11904.1 - 0.066 13.1 0.4 10 6.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAJ11904.1 - 0.11 12.6 0.6 4.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Mu-like_Com PF10122.9 OAJ11904.1 - 0.17 11.4 1.9 1.9 8.0 0.1 2.7 3 0 0 3 3 3 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.6 OAJ11904.1 - 0.64 9.8 2.9 79 3.1 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain TFIIS_C PF01096.18 OAJ11904.1 - 2.5 8.0 5.8 17 5.3 0.1 3.4 3 1 1 4 4 4 0 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 OAJ11904.1 - 8 6.2 6.0 23 4.7 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SWIRM-assoc_2 PF16496.5 OAJ11911.1 - 6.5e-31 107.6 0.3 5.5e-26 91.4 0.5 3.2 2 1 0 2 2 2 2 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 OAJ11911.1 - 1.4e-30 105.5 0.0 3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 OAJ11911.1 - 1.5e-29 101.7 6.0 4.1e-29 100.4 6.0 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAJ11911.1 - 5.2e-09 36.1 0.1 1.1e-08 35.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ11911.1 - 1.2e-07 31.8 0.0 3.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OAJ11911.1 - 2.4e-07 30.4 1.0 4.2e-07 29.7 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_7 PF15963.5 OAJ11911.1 - 0.17 11.8 0.1 0.57 10.1 0.1 1.8 1 0 0 1 1 1 0 Myb DNA-binding like Pkinase PF00069.25 OAJ11912.1 - 7.2e-60 202.6 0.0 3.2e-59 200.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11912.1 - 4.1e-41 141.0 0.0 5.8e-40 137.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 OAJ11912.1 - 6.6e-39 133.8 0.0 6.2e-38 130.6 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.6 OAJ11912.1 - 0.0014 18.0 0.0 0.25 10.6 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAJ11912.1 - 0.0047 15.8 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ11912.1 - 0.041 13.2 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ODC_AZ PF02100.17 OAJ11915.1 - 2.9e-10 40.1 0.0 5.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme LEAP-2 PF07359.11 OAJ11917.1 - 0.065 13.1 0.1 0.065 13.1 0.1 8.0 6 1 2 8 8 8 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Catalase PF00199.19 OAJ11923.1 - 1.9e-141 471.6 3.1 2.4e-96 323.2 0.1 2.1 2 0 0 2 2 2 2 Catalase Catalase-rel PF06628.12 OAJ11923.1 - 4.1e-19 68.5 0.0 8.2e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF5053 PF16476.5 OAJ11923.1 - 0.063 12.9 0.4 30 4.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) Trp_syntA PF00290.20 OAJ11924.1 - 5.6e-81 271.2 0.1 1.1e-80 270.3 0.1 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 OAJ11924.1 - 1.2e-49 169.3 0.7 1.2e-49 169.3 0.7 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 OAJ11924.1 - 0.0025 17.3 0.1 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein PA PF02225.22 OAJ11924.1 - 0.033 14.2 4.5 0.21 11.7 0.1 2.6 2 0 0 2 2 2 0 PA domain DFP PF04127.15 OAJ11924.1 - 0.056 13.3 0.4 0.66 9.8 0.1 2.6 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein PTR2 PF00854.21 OAJ11925.1 - 1.7e-79 267.5 7.4 1.7e-79 267.5 7.4 1.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 OAJ11925.1 - 5.4e-07 28.9 34.3 2.8e-05 23.2 34.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily GST_C_6 PF17171.4 OAJ11926.1 - 3.8e-06 26.6 0.0 1.1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAJ11926.1 - 1.3e-05 25.5 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SUIM_assoc PF16619.5 OAJ11927.1 - 1.8 8.7 9.3 0.15 12.1 2.4 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Epimerase PF01370.21 OAJ11934.1 - 2.8e-16 59.7 0.0 7.4e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ11934.1 - 1.4e-13 50.5 0.0 3.2e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ11934.1 - 8.2e-11 41.5 0.1 3e-09 36.4 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAJ11934.1 - 9.7e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ11934.1 - 3.2e-06 26.8 0.1 1.1e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 OAJ11934.1 - 0.085 11.9 0.0 0.25 10.4 0.0 1.8 3 0 0 3 3 3 0 RmlD substrate binding domain DUF1490 PF07371.12 OAJ11934.1 - 0.14 12.3 0.4 18 5.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) KR PF08659.10 OAJ11934.1 - 0.15 11.9 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 KR domain Ank_4 PF13637.6 OAJ11935.1 - 2e-20 72.8 0.7 4.5e-12 46.2 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ11935.1 - 5.8e-17 62.1 0.1 6.8e-09 36.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ11935.1 - 2.8e-14 52.8 0.0 0.00017 21.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAJ11935.1 - 9.3e-14 51.3 0.4 1.1e-06 28.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ11935.1 - 4.8e-11 41.9 0.1 0.005 17.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 OAJ11935.1 - 1.4e-05 24.9 1.8 0.0001 22.1 0.2 2.6 2 1 0 2 2 2 1 KilA-N domain Ribosomal_60s PF00428.19 OAJ11935.1 - 1.1 9.8 16.1 0.59 10.7 10.9 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4407 PF14362.6 OAJ11935.1 - 9.6 5.5 11.2 2.6 7.3 6.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Y_phosphatase2 PF03162.13 OAJ11936.1 - 7.5e-22 77.7 0.0 3.4e-12 46.3 0.0 2.4 3 0 0 3 3 3 2 Tyrosine phosphatase family Myc_N PF01056.18 OAJ11936.1 - 0.03 14.2 0.9 0.037 13.9 0.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NUT PF12881.7 OAJ11936.1 - 0.17 10.3 0.9 0.2 10.1 0.9 1.2 1 0 0 1 1 1 0 NUT protein Nucleo_P87 PF07267.11 OAJ11936.1 - 0.27 10.1 0.8 0.26 10.1 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 OAJ11936.1 - 0.6 9.4 14.8 0.87 8.8 14.8 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 OAJ11936.1 - 0.81 9.7 7.1 1.3 9.0 7.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 OAJ11936.1 - 0.94 9.3 10.6 1.6 8.6 10.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.11 OAJ11936.1 - 1.6 8.2 9.1 2.2 7.8 9.1 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 OAJ11936.1 - 3.1 7.0 9.6 5 6.4 9.6 1.3 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.12 OAJ11936.1 - 4.2 6.2 9.5 5.8 5.7 9.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RNA_pol_3_Rpc31 PF11705.8 OAJ11936.1 - 6 7.1 17.4 12 6.1 17.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 OAJ11936.1 - 7.6 5.9 12.5 12 5.2 12.5 1.2 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 OAJ11936.1 - 9.6 5.9 9.9 20 4.8 9.9 1.4 1 0 0 1 1 1 0 FAM176 family Peptidase_S9 PF00326.21 OAJ11937.1 - 1.9e-06 27.5 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ11937.1 - 0.0021 17.4 0.1 0.0092 15.3 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 zf-C3HC4_3 PF13920.6 OAJ11939.1 - 9.8e-09 34.9 7.1 3.4e-08 33.2 7.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ11939.1 - 1.5e-05 24.7 3.8 2.6e-05 24.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ11939.1 - 0.00034 20.9 5.1 0.00071 19.9 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ11939.1 - 0.0011 18.9 3.5 0.0018 18.2 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ11939.1 - 0.0016 18.3 5.0 0.013 15.4 5.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAJ11939.1 - 0.0053 16.7 3.4 0.022 14.8 1.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ11939.1 - 0.11 12.4 5.9 0.055 13.3 2.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAJ11939.1 - 0.95 9.3 3.2 2.4 8.0 3.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain muHD PF10291.9 OAJ11940.1 - 1.1e-36 126.6 0.0 1.9e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 OAJ11940.1 - 1.1e-06 28.8 1.1 4.5e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain APG6_N PF17675.1 OAJ11940.1 - 0.0056 17.2 1.0 0.0056 17.2 1.0 2.3 2 0 0 2 2 2 1 Apg6 coiled-coil region PKcGMP_CC PF16808.5 OAJ11940.1 - 0.012 15.5 0.3 0.027 14.3 0.3 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Kre28 PF17097.5 OAJ11940.1 - 0.017 14.1 1.9 0.025 13.5 1.9 1.1 1 0 0 1 1 1 0 Spindle pole body component Exonuc_VII_L PF02601.15 OAJ11940.1 - 0.069 12.7 2.7 0.12 11.9 2.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.9 OAJ11940.1 - 0.12 11.3 1.6 0.2 10.6 1.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 HrpB7 PF09486.10 OAJ11940.1 - 0.21 12.0 10.0 0.049 14.0 4.3 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.9 OAJ11940.1 - 1.5 7.8 4.7 3.1 6.8 4.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SecE PF00584.20 OAJ11951.1 - 3.4e-15 55.7 0.0 4.1e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF2767 PF10965.8 OAJ11951.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Nop53 PF07767.11 OAJ11952.1 - 7.2 5.9 24.1 0.16 11.3 5.6 3.5 3 0 0 3 3 3 0 Nop53 (60S ribosomal biogenesis) PPR PF01535.20 OAJ11953.1 - 7.5e-09 35.2 0.0 0.28 11.5 0.0 4.5 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 OAJ11953.1 - 1e-05 25.6 0.0 1.3 9.2 0.0 4.1 4 0 0 4 4 4 3 PPR repeat family PPR_1 PF12854.7 OAJ11953.1 - 0.00065 19.3 1.0 0.042 13.5 0.2 2.6 2 0 0 2 2 2 2 PPR repeat Aminotran_1_2 PF00155.21 OAJ11954.1 - 1.3e-36 126.6 0.0 9.7e-36 123.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ11954.1 - 0.00087 17.9 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3153 PF11353.8 OAJ11954.1 - 0.012 15.2 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Pox_Ag35 PF03286.14 OAJ11955.1 - 0.23 11.2 1.0 0.45 10.3 0.2 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 OAJ11955.1 - 0.74 9.8 5.4 0.3 11.1 0.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Spt5_N PF11942.8 OAJ11955.1 - 1 10.4 6.7 0.22 12.5 1.1 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-CCHC_4 PF14392.6 OAJ11961.1 - 0.19 11.5 1.4 0.5 10.1 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle MULE PF10551.9 OAJ11962.1 - 9.5e-18 64.4 0.0 2.3e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ11962.1 - 4.1e-05 22.6 0.0 6.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Tim44 PF04280.15 OAJ11965.1 - 9.6e-20 71.2 0.1 1.9e-14 54.0 0.0 3.3 2 1 1 3 3 3 2 Tim44-like domain GRP PF07172.11 OAJ11965.1 - 0.93 10.2 10.2 0.039 14.6 3.3 2.2 2 0 0 2 2 2 0 Glycine rich protein family CIA30 PF08547.12 OAJ11966.1 - 1.3e-20 74.0 0.0 2.2e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 OAJ11966.1 - 0.073 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Ammonium_transp PF00909.21 OAJ11974.1 - 9.8e-105 350.5 31.1 1.2e-104 350.2 31.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.6 OAJ11974.1 - 0.53 10.9 6.6 0.7 10.5 4.7 2.3 2 0 0 2 2 2 0 Putative membrane protein G_glu_transpept PF01019.21 OAJ11975.1 - 1.6e-57 195.5 0.1 9.9e-43 146.7 0.0 2.0 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase ANAPC4 PF12896.7 OAJ11976.1 - 6e-22 78.2 0.2 1e-21 77.4 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF2285 PF10074.9 OAJ11976.1 - 0.089 13.5 1.8 0.18 12.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Mago_nashi PF02792.14 OAJ11977.1 - 6e-76 253.4 0.4 6.7e-76 253.2 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein ER_lumen_recept PF00810.18 OAJ11978.1 - 9.8e-50 169.2 2.9 1.6e-49 168.5 2.9 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAJ11978.1 - 0.00025 20.7 9.9 0.012 15.4 0.8 4.1 4 0 0 4 4 4 2 PQ loop repeat 40S_S4_C PF16121.5 OAJ11978.1 - 0.15 11.7 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus YCII PF03795.14 OAJ11979.1 - 0.006 17.0 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 YCII-related domain EcsC PF12787.7 OAJ11979.1 - 0.057 13.1 1.4 0.084 12.5 1.4 1.2 1 0 0 1 1 1 0 EcsC protein family LysM PF01476.20 OAJ11980.1 - 3.1e-12 46.3 0.0 3.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 LysM domain bZIP_1 PF00170.21 OAJ11981.1 - 9.3e-08 32.1 2.0 2.1e-07 31.0 2.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ11981.1 - 0.018 15.1 2.6 0.043 13.9 2.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Trehalase_Ca-bi PF07492.11 OAJ11991.1 - 0.21 11.3 0.8 0.42 10.4 0.8 1.5 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain RRM_1 PF00076.22 OAJ11992.1 - 3.2e-10 39.7 0.0 3.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ11992.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ11992.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PTPA PF03095.15 OAJ11993.1 - 3.8e-97 325.4 0.0 5.3e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Herpes_pp85 PF04637.12 OAJ11993.1 - 2.2 6.6 3.2 3.4 6.0 3.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Glyco_hydro_88 PF07470.13 OAJ11994.1 - 5.7e-11 42.1 1.3 2.1e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 SecY PF00344.20 OAJ11995.1 - 2.8e-74 250.1 8.1 3.4e-74 249.9 8.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAJ11995.1 - 9e-17 60.6 0.3 2.5e-16 59.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.11 OAJ11995.1 - 0.95 9.4 5.7 1.5 8.8 0.0 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Acyltransferase PF01553.21 OAJ12004.1 - 0.18 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Acyltransferase TatD_DNase PF01026.21 OAJ12005.1 - 4.6e-49 167.1 0.0 6.8e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase His_Phos_1 PF00300.22 OAJ12006.1 - 4.1e-19 69.0 6.1 7.5e-12 45.3 1.5 5.0 4 2 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) Molybdopterin PF00384.22 OAJ12007.1 - 4.8e-73 246.6 0.0 4.8e-37 127.9 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 OAJ12007.1 - 1.9e-18 66.3 0.0 6.8e-18 64.5 0.0 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 OAJ12007.1 - 3.1e-15 55.4 0.1 3.1e-15 55.4 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 OAJ12007.1 - 3.7e-14 53.1 0.0 1.3e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 OAJ12007.1 - 5.4e-08 32.7 1.8 5.7e-08 32.6 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 OAJ12007.1 - 0.022 14.5 0.1 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 OAJ12007.1 - 0.27 11.1 1.4 6.3 6.8 0.4 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain HSP70 PF00012.20 OAJ12008.1 - 8.6e-256 849.8 13.2 9.9e-256 849.6 13.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ12008.1 - 3.3e-19 68.9 0.9 4.4e-17 61.9 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.10 OAJ12008.1 - 0.0026 16.8 0.8 0.063 12.3 0.5 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 OAJ12008.1 - 0.012 16.1 1.0 18 5.8 0.0 3.4 3 0 0 3 3 3 0 Cell division protein FtsA FGGY_C PF02782.16 OAJ12008.1 - 0.015 15.0 0.0 0.062 13.0 0.0 2.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Spectrin PF00435.21 OAJ12008.1 - 0.046 14.2 3.7 4.4 7.9 0.4 2.8 2 0 0 2 2 2 0 Spectrin repeat Hydantoinase_A PF01968.18 OAJ12008.1 - 0.09 12.0 2.8 0.18 11.0 0.2 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase TRAF_BIRC3_bd PF16673.5 OAJ12008.1 - 3 7.7 5.2 5.3 6.9 0.2 3.3 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain GCFC PF07842.12 OAJ12009.1 - 7.3e-67 225.9 13.9 1.1e-66 225.3 13.9 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAJ12009.1 - 2e-07 30.8 0.2 2e-07 30.8 0.2 2.9 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 OAJ12009.1 - 0.00055 20.0 4.8 0.0045 17.1 0.2 3.8 3 1 1 4 4 4 1 G-patch domain RabGAP-TBC PF00566.18 OAJ12014.1 - 7.6e-46 156.5 0.0 1.1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Asp_protease PF09668.10 OAJ12015.1 - 4e-58 194.6 0.0 6e-58 194.0 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ12015.1 - 1.9e-20 73.2 0.0 4.8e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ12015.1 - 4.9e-09 36.7 0.0 1.2e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 OAJ12015.1 - 9e-08 31.8 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ12015.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain TFIIA PF03153.13 OAJ12015.1 - 0.0079 16.2 9.3 0.011 15.8 9.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RVP PF00077.20 OAJ12015.1 - 0.011 16.1 0.8 0.027 14.8 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Rad60-SLD PF11976.8 OAJ12015.1 - 0.013 15.3 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Spt20 PF12090.8 OAJ12015.1 - 0.029 14.0 10.8 0.051 13.2 10.8 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 OAJ12015.1 - 0.18 10.9 4.9 0.36 9.9 4.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein ANAPC_CDC26 PF10471.9 OAJ12015.1 - 0.64 10.9 17.1 0.062 14.1 9.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 SF3b10 PF07189.11 OAJ12017.1 - 0.065 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) 2OG-FeII_Oxy_3 PF13640.6 OAJ12017.1 - 0.079 13.9 0.0 0.17 12.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Oxysterol_BP PF01237.18 OAJ12018.1 - 2e-41 142.1 2.0 1.3e-24 86.8 2.6 3.8 2 1 0 2 2 2 2 Oxysterol-binding protein DUF3408 PF11888.8 OAJ12018.1 - 3.7 7.7 7.3 0.32 11.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) PEMT PF04191.13 OAJ12019.1 - 1.5e-34 118.6 6.2 1.5e-34 118.6 6.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF2157 PF09925.9 OAJ12019.1 - 0.22 11.3 3.3 1.5 8.6 0.0 2.9 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF3323 PF11796.8 OAJ12020.1 - 0.022 14.6 0.1 0.05 13.5 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) MFS_1 PF07690.16 OAJ12021.1 - 4.5e-43 147.5 21.0 2.6e-38 131.9 15.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ12021.1 - 4.6e-08 32.4 7.2 4.6e-08 32.4 7.2 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAJ12021.1 - 0.0019 16.6 0.0 0.075 11.3 0.0 2.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 OAJ12021.1 - 0.34 9.7 16.9 0.073 11.9 0.8 4.2 4 1 1 5 5 5 0 MFS_1 like family COesterase PF00135.28 OAJ12022.1 - 4.4e-62 210.6 1.0 1.1e-53 182.9 0.5 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ12022.1 - 3e-06 27.2 0.1 1.3e-05 25.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ12022.1 - 0.0075 16.9 1.7 0.021 15.4 1.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pro_isomerase PF00160.21 OAJ12031.1 - 1.6e-14 54.5 0.0 8.5e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2406 PF10295.9 OAJ12031.1 - 0.035 14.8 2.2 6.2 7.6 0.4 2.5 1 1 1 2 2 2 0 Uncharacterised protein (DUF2406) DUF1180 PF06679.12 OAJ12032.1 - 0.15 12.4 2.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Serglycin PF04360.12 OAJ12032.1 - 1.3 8.9 6.8 3.9 7.4 6.8 1.8 1 0 0 1 1 1 0 Serglycin EF-hand_7 PF13499.6 OAJ12034.1 - 2.7e-12 46.9 0.1 2.3e-07 31.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ12034.1 - 3.9e-12 45.0 0.2 3e-05 23.6 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OAJ12034.1 - 2.5e-11 42.3 0.0 1.3e-05 24.3 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAJ12034.1 - 8.3e-10 38.8 0.0 9.6e-06 25.8 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAJ12034.1 - 4.7e-05 23.1 0.4 0.0077 16.1 0.0 3.3 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ12034.1 - 0.00054 19.3 0.4 0.026 14.0 0.0 2.8 2 1 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 OAJ12034.1 - 0.025 15.5 0.0 0.037 14.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain EFhand_Ca_insen PF08726.10 OAJ12034.1 - 0.17 12.0 0.0 1 9.5 0.0 2.2 2 1 0 2 2 2 0 Ca2+ insensitive EF hand ExbD PF02472.16 OAJ12034.1 - 0.19 11.9 0.0 0.54 10.4 0.0 1.6 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR TFIID-18kDa PF02269.16 OAJ12035.1 - 1.2e-16 60.5 0.0 5.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit ThiF PF00899.21 OAJ12036.1 - 4.5e-35 121.2 0.0 1.2e-34 119.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family TrkA_N PF02254.18 OAJ12036.1 - 0.077 13.3 0.1 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain GTP_cyclohydro2 PF00925.20 OAJ12037.1 - 9.4e-60 200.9 0.0 2e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II Spt20 PF12090.8 OAJ12037.1 - 9.6 5.7 12.0 21 4.6 12.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF1295 PF06966.12 OAJ12038.1 - 2.4e-34 118.9 0.0 1.3e-33 116.4 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 OAJ12039.1 - 5.2e-15 55.2 9.5 1.9e-06 27.0 0.0 3.8 3 1 0 4 4 4 3 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ12039.1 - 2.2e-05 23.2 3.3 0.0001 21.0 0.2 2.9 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 OAJ12039.1 - 0.015 14.2 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 MFS_1 like family DUF4481 PF14800.6 OAJ12039.1 - 0.063 12.8 0.2 0.14 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) SPX PF03105.19 OAJ12053.1 - 6 6.7 19.6 7.7 6.3 19.6 1.1 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 OAJ12053.1 - 9.9 5.6 7.6 14 5.1 7.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NDC10_II PF16787.5 OAJ12054.1 - 3.9e-14 52.4 0.0 5.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 NifZ PF04319.13 OAJ12056.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 NifZ domain DAO PF01266.24 OAJ12062.1 - 3.9e-43 148.4 1.5 1.9e-42 146.2 1.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ12062.1 - 0.00017 21.8 0.1 0.0004 20.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ12062.1 - 0.068 12.4 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.15 OAJ12062.1 - 0.098 11.2 0.3 0.16 10.5 0.0 1.4 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 OAJ12062.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ12062.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 OAJ12062.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SnoaL_2 PF12680.7 OAJ12062.1 - 0.14 12.8 0.0 0.36 11.5 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain DUF737 PF05300.11 OAJ12064.1 - 0.0049 17.3 10.6 0.0049 17.3 10.6 6.7 6 2 0 6 6 6 1 Protein of unknown function (DUF737) Translin PF01997.16 OAJ12065.1 - 1.6e-46 158.9 0.2 3e-34 118.8 0.0 2.3 1 1 1 2 2 2 2 Translin family UPF0164 PF03687.13 OAJ12065.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0164) HisKA PF00512.25 OAJ12065.1 - 0.16 12.0 2.4 0.31 11.1 0.2 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Dicty_REP PF05086.12 OAJ12065.1 - 0.26 9.2 0.5 0.43 8.5 0.5 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RT_RNaseH PF17917.1 OAJ12073.1 - 4.4e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ12073.1 - 7.8e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ12074.1 - 1.2e-32 113.3 0.0 1.8e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TrmB PF01978.19 OAJ12074.1 - 0.0078 16.1 0.1 21 5.1 0.0 4.5 5 0 0 5 5 5 1 Sugar-specific transcriptional regulator TrmB ATG_C PF09333.11 OAJ12076.1 - 5e-30 103.7 0.3 2.2e-29 101.7 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 OAJ12076.1 - 7e-11 42.3 0.1 1.6e-05 25.0 0.0 2.8 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 OAJ12076.1 - 1.4e-06 28.1 0.0 7.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 OAJ12076.1 - 0.0013 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal eIF-1a PF01176.19 OAJ12077.1 - 2.2e-21 75.4 0.0 3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 tRNA-synt_2b PF00587.25 OAJ12079.1 - 5.4e-16 59.1 0.0 6.2e-14 52.4 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DPM3 PF08285.11 OAJ12080.1 - 3.8e-29 100.7 0.0 4.3e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DHR10 PF18595.1 OAJ12081.1 - 0.0053 16.8 0.2 0.01 15.9 0.2 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Fez1 PF06818.15 OAJ12081.1 - 0.023 15.1 0.1 0.038 14.4 0.1 1.3 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 OAJ12081.1 - 0.031 14.9 2.1 0.067 13.8 2.1 1.5 1 0 0 1 1 1 0 SlyX PC4 PF02229.16 OAJ12081.1 - 0.073 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) IL32 PF15225.6 OAJ12081.1 - 0.1 13.0 0.3 0.17 12.3 0.3 1.3 1 0 0 1 1 1 0 Interleukin 32 zf-CCHC PF00098.23 OAJ12082.1 - 7.2e-08 32.2 0.9 1.2e-07 31.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ12082.1 - 0.0089 15.7 2.9 0.016 14.9 2.9 1.3 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger gag-asp_proteas PF13975.6 OAJ12083.1 - 1.1e-08 35.5 0.0 1.7e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ12083.1 - 4.8e-07 30.3 0.1 7.4e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OAJ12083.1 - 0.00033 20.4 0.0 0.00046 20.0 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 OAJ12083.1 - 0.0063 16.1 0.0 0.0078 15.8 0.0 1.1 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.10 OAJ12083.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease PDT PF00800.18 OAJ12090.1 - 7.2e-40 136.7 0.3 1.9e-34 119.1 0.0 3.2 2 1 1 3 3 3 3 Prephenate dehydratase Pkinase PF00069.25 OAJ12091.1 - 2.1e-34 119.1 0.0 2e-10 40.5 0.0 4.3 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12091.1 - 1e-15 57.8 0.0 2.5e-08 33.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ12091.1 - 0.0045 16.9 0.1 0.0045 16.9 0.1 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family F-box PF00646.33 OAJ12091.1 - 0.081 12.8 1.6 0.23 11.4 1.6 1.7 1 0 0 1 1 1 0 F-box domain ubiquitin PF00240.23 OAJ12092.1 - 4.2e-33 112.9 0.5 5.6e-33 112.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OAJ12092.1 - 4.6e-29 100.1 9.0 7e-29 99.5 9.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OAJ12092.1 - 3.8e-15 55.5 0.5 5e-15 55.1 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ12092.1 - 0.00013 22.3 0.1 0.0005 20.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ12092.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ12092.1 - 0.016 15.3 0.1 0.027 14.6 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ12092.1 - 0.032 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 OAJ12092.1 - 0.042 14.4 0.1 0.069 13.7 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ12092.1 - 0.12 12.4 1.0 6.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_L18A PF01775.17 OAJ12093.1 - 4.3e-53 178.5 0.2 5.1e-53 178.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Stimulus_sens_1 PF13756.6 OAJ12093.1 - 0.11 13.0 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Stimulus-sensing domain Phage_integrase PF00589.22 OAJ12094.1 - 2.9e-05 23.9 0.0 3.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family RT_RNaseH_2 PF17919.1 OAJ12095.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Actin PF00022.19 OAJ12096.1 - 6.1e-149 496.1 0.0 2.8e-148 493.9 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 OAJ12096.1 - 0.018 13.6 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.32 OAJ12106.1 - 1.5e-06 28.8 9.5 3.1 8.8 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 OAJ12106.1 - 0.00091 19.0 0.6 0.015 15.1 0.0 3.1 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Polysacc_deac_1 PF01522.21 OAJ12107.1 - 2.1e-14 53.5 0.0 5.8e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Nudix_N PF12535.8 OAJ12108.1 - 0.083 12.5 0.0 31 4.3 0.0 3.1 3 0 0 3 3 3 0 Hydrolase of X-linked nucleoside diphosphate N terminal LrgB PF04172.16 OAJ12108.1 - 0.32 10.5 8.3 17 4.9 0.1 3.8 4 0 0 4 4 4 0 LrgB-like family Ribophorin_I PF04597.14 OAJ12109.1 - 3.6e-113 379.1 0.3 3.6e-112 375.8 0.3 1.9 1 1 0 1 1 1 1 Ribophorin I MBOAT_2 PF13813.6 OAJ12110.1 - 3.4e-12 46.5 0.0 7.7e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family FMO-like PF00743.19 OAJ12111.1 - 3.1e-10 39.1 0.2 9.1e-08 31.0 0.2 3.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ12111.1 - 7.7e-09 35.2 0.0 0.002 17.4 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ12111.1 - 2.7e-08 33.9 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAJ12111.1 - 6e-08 32.8 0.2 0.0006 19.8 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ12111.1 - 1.7e-06 27.6 0.0 0.091 12.0 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ12111.1 - 2.1e-06 27.2 0.4 0.00028 20.1 0.1 3.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAJ12111.1 - 0.00018 21.3 0.3 0.0089 15.7 0.1 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 OAJ12111.1 - 0.034 13.2 0.1 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAJ12111.1 - 0.13 11.4 0.0 0.67 9.1 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 OAJ12111.1 - 0.19 11.8 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase EamA PF00892.20 OAJ12116.1 - 1.5e-20 73.8 37.6 1.3e-12 48.1 11.0 3.8 2 2 1 3 3 3 3 EamA-like transporter family PBP_N PF17093.5 OAJ12116.1 - 0.013 15.7 1.4 0.017 15.4 0.2 1.8 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus DUF3021 PF11457.8 OAJ12116.1 - 2.6 8.4 9.2 0.1 12.9 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) His_Phos_1 PF00300.22 OAJ12117.1 - 1.8e-08 34.3 0.0 3.7e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Acyl_transf_1 PF00698.21 OAJ12120.1 - 1.3e-09 38.0 3.1 1.5e-05 24.7 0.0 3.4 3 1 0 3 3 3 2 Acyl transferase domain Hexapep PF00132.24 OAJ12121.1 - 4.7e-12 45.1 2.6 9.4e-10 37.8 1.5 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ12121.1 - 8.5e-11 41.4 4.5 9.7e-10 38.0 2.5 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAJ12121.1 - 2e-10 40.7 0.0 5.5e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Maltose acetyltransferase DUF4115 PF13464.6 OAJ12121.1 - 0.022 14.9 0.1 0.058 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) RPAP1_N PF08621.10 OAJ12122.1 - 9.1e-09 35.0 0.6 1.8e-08 34.0 0.6 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 OAJ12122.1 - 0.00089 19.3 0.2 0.0032 17.5 0.2 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal Ribosomal_L4 PF00573.22 OAJ12122.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family Cytokin_check_N PF10407.9 OAJ12122.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus FAM76 PF16046.5 OAJ12122.1 - 4.9 6.4 8.2 0.092 12.1 0.6 1.9 3 0 0 3 3 3 0 FAM76 protein Hexapep PF00132.24 OAJ12123.1 - 2.4e-11 42.9 5.8 8.7e-10 37.9 2.8 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ12123.1 - 9.8e-11 41.2 6.1 4.4e-10 39.1 2.9 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAJ12123.1 - 5.7e-10 39.3 0.0 1.6e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase RT_RNaseH PF17917.1 OAJ12131.1 - 8.2e-11 42.1 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ12131.1 - 6.8e-05 22.8 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_3 PF12776.7 OAJ12134.1 - 5.9e-10 40.0 0.7 9.7e-10 39.3 0.7 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain CNDH2_C PF16858.5 OAJ12136.1 - 0.00062 19.7 5.0 0.00075 19.5 5.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 OAJ12136.1 - 0.0014 16.9 8.3 0.0015 16.9 8.3 1.0 1 0 0 1 1 1 1 Nop14-like family Nop25 PF09805.9 OAJ12136.1 - 0.0057 17.1 3.6 0.0075 16.7 3.6 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 OAJ12136.1 - 0.0072 15.7 11.9 0.0083 15.5 11.9 1.1 1 0 0 1 1 1 1 BUD22 DNA_pol_phi PF04931.13 OAJ12136.1 - 0.023 12.8 18.6 0.028 12.5 18.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 OAJ12136.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ12136.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF2722 PF10846.8 OAJ12136.1 - 0.25 10.2 10.0 0.31 9.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 OAJ12136.1 - 0.52 9.7 18.6 0.64 9.4 18.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ12136.1 - 1.4 7.1 12.9 1.6 6.9 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Drc1-Sld2 PF11719.8 OAJ12136.1 - 1.5 8.3 9.4 2.1 7.8 9.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein PPP4R2 PF09184.11 OAJ12136.1 - 3 7.4 14.7 3.7 7.0 14.7 1.2 1 0 0 1 1 1 0 PPP4R2 FYDLN_acid PF09538.10 OAJ12136.1 - 3.3 8.4 19.4 6.5 7.5 19.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pes-10 PF07149.11 OAJ12136.1 - 5.7 5.9 17.0 7.2 5.6 17.0 1.1 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 OAJ12136.1 - 6.4 5.8 27.0 8.7 5.4 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 OAJ12136.1 - 7.9 5.1 8.0 9.2 4.9 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rad60-SLD PF11976.8 OAJ12144.1 - 8.1e-13 48.0 0.9 1.7e-12 47.0 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ12144.1 - 2.4e-05 24.0 0.5 4.7e-05 23.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family SURF6 PF04935.12 OAJ12144.1 - 0.91 9.3 17.4 3.7 7.3 3.7 2.6 2 0 0 2 2 2 0 Surfeit locus protein 6 Peptidase_S8 PF00082.22 OAJ12145.1 - 2.5e-32 112.4 0.0 9.1e-32 110.5 0.0 1.9 2 1 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 OAJ12145.1 - 4.1e-18 66.2 0.2 1e-17 64.9 0.2 1.7 1 0 0 1 1 1 1 Fn3-like domain CBM_4_9 PF02018.17 OAJ12145.1 - 0.02 15.2 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain ASH PF15780.5 OAJ12145.1 - 0.14 12.4 0.0 5 7.4 0.0 3.2 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin COesterase PF00135.28 OAJ12146.1 - 1.2e-90 304.9 0.4 1.5e-90 304.6 0.4 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ12146.1 - 1.7e-07 31.3 0.4 0.0018 18.2 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold EcKinase PF02958.20 OAJ12147.1 - 1.1e-12 47.9 0.0 4.3e-08 32.8 0.0 2.4 3 0 0 3 3 3 2 Ecdysteroid kinase DUF1679 PF07914.11 OAJ12147.1 - 1e-08 34.5 0.0 2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 OAJ12147.1 - 7.5e-07 29.3 0.1 3.3e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Jnk-SapK_ap_N PF09744.9 OAJ12149.1 - 0.055 13.7 3.5 0.78 10.0 0.5 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HTH_Tnp_Tc5 PF03221.16 OAJ12157.1 - 7e-05 22.8 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.6 OAJ12157.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.6 OAJ12157.1 - 0.003 17.3 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.7 OAJ12157.1 - 0.004 17.0 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.22 OAJ12157.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_28 PF13518.6 OAJ12157.1 - 0.012 15.7 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 OAJ12157.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain ApoO PF09769.9 OAJ12157.1 - 0.035 14.1 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein O CENP-B_N PF04218.13 OAJ12157.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Pox_Ag35 PF03286.14 OAJ12157.1 - 0.85 9.4 10.8 1.5 8.6 10.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pho88 PF10032.9 OAJ12158.1 - 8.7e-63 210.9 0.0 9.6e-63 210.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4729 PF15866.5 OAJ12158.1 - 0.16 11.3 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) zf-CHCC PF10276.9 OAJ12159.1 - 1.2e-17 63.7 1.5 1.7e-17 63.1 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Hamartin PF04388.12 OAJ12159.1 - 6 5.4 7.8 6.7 5.2 7.8 1.0 1 0 0 1 1 1 0 Hamartin protein RVT_1 PF00078.27 OAJ12160.1 - 5.6e-24 84.9 0.0 7.4e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med21 PF11221.8 OAJ12162.1 - 4.9e-15 56.0 1.0 6.3e-15 55.7 1.0 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex LMP PF04778.12 OAJ12162.1 - 0.029 14.3 0.4 0.037 13.9 0.4 1.1 1 0 0 1 1 1 0 LMP repeated region Macoilin PF09726.9 OAJ12162.1 - 0.036 12.6 0.9 0.039 12.5 0.9 1.0 1 0 0 1 1 1 0 Macoilin family FUSC PF04632.12 OAJ12162.1 - 0.12 10.8 4.8 0.14 10.7 4.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spc7 PF08317.11 OAJ12162.1 - 0.84 8.5 6.3 0.98 8.2 6.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Snf7 PF03357.21 OAJ12163.1 - 1.8e-36 125.3 16.5 1.8e-36 125.3 16.5 1.6 2 0 0 2 2 2 1 Snf7 PspA_IM30 PF04012.12 OAJ12163.1 - 0.021 14.4 17.3 0.04 13.5 5.7 2.1 1 1 1 2 2 2 0 PspA/IM30 family GIT_CC PF16559.5 OAJ12163.1 - 0.095 12.6 3.4 4.8 7.1 0.1 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_MLP1_2 PF07926.12 OAJ12163.1 - 0.11 12.6 8.5 0.25 11.4 8.1 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YlqD PF11068.8 OAJ12163.1 - 1.1 9.7 12.1 3.4 8.1 10.8 2.0 1 1 1 2 2 2 0 YlqD protein ADK PF00406.22 OAJ12164.1 - 6.4e-46 156.2 0.0 7.9e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ12164.1 - 5e-34 117.6 0.0 7.1e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ12164.1 - 4.3e-11 43.5 0.0 5.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAJ12164.1 - 3.3e-07 30.2 0.2 0.009 15.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 OAJ12164.1 - 0.012 15.7 0.0 0.049 13.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 OAJ12164.1 - 0.069 13.0 0.4 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 OAJ12164.1 - 0.16 11.3 1.1 1 8.6 1.1 2.0 1 1 0 1 1 1 0 Zeta toxin CTK3 PF12243.8 OAJ12165.1 - 6e-22 77.9 0.2 1e-20 73.9 0.2 2.2 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAJ12165.1 - 2.1e-18 66.3 1.8 8.2e-11 41.9 0.3 3.2 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 C-terminus zf-C3HC4_3 PF13920.6 OAJ12166.1 - 8.1e-11 41.6 11.9 1.3e-10 41.0 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ12166.1 - 0.0014 18.5 11.5 0.0024 17.7 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Tub_N PF16322.5 OAJ12166.1 - 1.1 9.6 5.9 3.1 8.2 5.9 1.7 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 OAJ12166.1 - 7.6 5.8 14.7 14 4.9 14.7 1.3 1 0 0 1 1 1 0 BUD22 zf-RING_2 PF13639.6 OAJ12166.1 - 9.3 6.7 14.5 15 6.0 14.5 1.3 1 0 0 1 1 1 0 Ring finger domain Cep57_MT_bd PF06657.13 OAJ12175.1 - 0.043 14.3 0.5 0.076 13.5 0.4 1.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 OAJ12175.1 - 0.043 14.0 0.6 0.049 13.9 0.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DMPK_coil PF08826.10 OAJ12175.1 - 0.13 12.4 0.7 0.25 11.5 0.6 1.7 1 1 0 1 1 1 0 DMPK coiled coil domain like Mrx7 PF10906.8 OAJ12184.1 - 0.017 15.4 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 MIOREX complex component 7 PHD PF00628.29 OAJ12185.1 - 0.55 10.2 5.7 0.87 9.5 5.7 1.3 1 0 0 1 1 1 0 PHD-finger RRN3 PF05327.11 OAJ12186.1 - 2.6 6.5 4.1 3.6 6.0 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4712 PF15830.5 OAJ12197.1 - 0.37 10.4 3.5 0.69 9.5 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) Abhydrolase_3 PF07859.13 OAJ12198.1 - 2e-08 34.4 0.0 2.9e-08 33.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ12198.1 - 0.026 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase HMGL-like PF00682.19 OAJ12199.1 - 7.3e-81 271.6 0.5 1.2e-80 270.9 0.5 1.4 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 OAJ12199.1 - 0.021 15.4 0.6 0.043 14.3 0.6 1.5 1 0 0 1 1 1 0 FliG N-terminal domain cpYpsA PF12694.7 OAJ12199.1 - 0.046 13.5 0.1 4.3 7.1 0.0 2.9 3 0 0 3 3 3 0 Circularly permutated YpsA SLOG family ParD PF09386.10 OAJ12199.1 - 0.34 11.3 2.1 1.1 9.7 2.1 1.9 1 1 0 1 1 1 0 Antitoxin ParD DUF4965 PF16335.5 OAJ12200.1 - 6.2e-66 221.3 0.0 1.1e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAJ12200.1 - 3.7e-62 209.7 0.5 7.5e-62 208.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAJ12200.1 - 5.5e-48 163.7 1.8 1.3e-47 162.5 1.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ12200.1 - 2.5e-05 23.7 2.0 0.053 13.1 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ12200.1 - 0.00048 19.7 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Utp14 PF04615.13 OAJ12201.1 - 5.7e-11 41.8 3.7 5.7e-11 41.8 3.7 1.5 2 0 0 2 2 2 1 Utp14 protein HEPN_MAE_28990 PF18737.1 OAJ12201.1 - 0.056 13.4 0.3 0.076 12.9 0.3 1.1 1 0 0 1 1 1 0 MAE_28990/MAE_18760-like HEPN UPF0113_N PF17833.1 OAJ12202.1 - 3.5e-28 98.0 0.0 5.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAJ12202.1 - 6.5e-23 80.8 0.0 1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 OAJ12202.1 - 0.048 13.7 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Utp14 PF04615.13 OAJ12203.1 - 1.1e-73 249.1 13.1 1.2e-73 249.0 13.1 1.0 1 0 0 1 1 1 1 Utp14 protein PI3_PI4_kinase PF00454.27 OAJ12204.1 - 6.1e-34 118.0 0.0 1.3e-31 110.3 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAJ12204.1 - 2.4e-27 95.5 0.2 4.2e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Zn_clus PF00172.18 OAJ12213.1 - 0.0049 16.9 15.5 0.0072 16.4 15.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LTV PF04180.14 OAJ12214.1 - 2.7e-75 254.5 4.9 2.7e-75 254.5 4.9 2.2 1 1 1 2 2 2 1 Low temperature viability protein SUIM_assoc PF16619.5 OAJ12214.1 - 0.13 12.3 6.2 0.31 11.2 0.1 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PCM1_C PF15717.5 OAJ12214.1 - 4 6.0 14.3 0.12 11.1 5.9 2.2 2 0 0 2 2 2 0 Pericentriolar material 1 C terminus RabGAP-TBC PF00566.18 OAJ12215.1 - 1.6e-21 77.0 2.8 1.2e-17 64.3 1.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain CwfJ_C_2 PF04676.14 OAJ12216.1 - 5.1e-33 113.9 0.2 1.1e-32 112.9 0.2 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAJ12216.1 - 1.2e-27 96.2 0.1 1.7e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Sorting_nexin PF03700.13 OAJ12227.1 - 0.05 14.2 4.0 0.11 13.1 4.0 1.5 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain DUF2610 PF11020.8 OAJ12228.1 - 0.045 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) GATA PF00320.27 OAJ12229.1 - 0.00012 21.6 1.9 0.00022 20.7 1.9 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF5633 PF18656.1 OAJ12229.1 - 4.3 7.3 5.4 1.4 8.8 2.2 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5633) DUF3323 PF11796.8 OAJ12230.1 - 0.00025 21.0 9.7 0.0025 17.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function N-terminus (DUF3323) Pcc1 PF09341.10 OAJ12231.1 - 1.3e-18 66.9 1.0 1.6e-18 66.6 1.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 WD40 PF00400.32 OAJ12232.1 - 8.9e-58 190.9 11.1 3.8e-08 33.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 OAJ12232.1 - 6.2e-22 77.7 3.9 6.2e-22 77.7 3.9 2.0 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 OAJ12232.1 - 6.2e-21 74.5 0.0 1.5e-05 25.2 0.0 6.3 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAJ12232.1 - 2e-10 40.5 0.0 0.023 14.0 0.0 4.6 4 1 1 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 OAJ12232.1 - 4.8e-08 32.3 0.1 1 8.3 0.0 5.8 3 3 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ12232.1 - 3.3e-05 23.7 0.5 14 5.8 0.0 5.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat TFIIA PF03153.13 OAJ12232.1 - 0.00059 19.9 30.5 0.00059 19.9 30.5 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nup160 PF11715.8 OAJ12232.1 - 0.0099 14.6 0.6 4.9 5.7 0.1 3.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Spt20 PF12090.8 OAJ12232.1 - 4.8 6.7 36.3 0.45 10.1 26.6 2.4 2 0 0 2 2 2 0 Spt20 family RNA_pol_Rpb8 PF03870.15 OAJ12241.1 - 4.4e-45 153.3 0.0 6e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.17 OAJ12242.1 - 4.3e-52 176.7 0.0 2.4e-26 92.3 0.0 2.4 2 1 0 2 2 2 2 Polyprenyl synthetase zinc_ribbon_10 PF10058.9 OAJ12243.1 - 2e-15 56.2 0.0 3.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 OAJ12243.1 - 0.00071 19.0 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Mu-like prophage protein Com TFIIA PF03153.13 OAJ12243.1 - 0.072 13.1 10.7 0.13 12.2 10.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn-ribbon_8 PF09723.10 OAJ12243.1 - 0.28 11.3 1.1 0.62 10.2 1.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Spt20 PF12090.8 OAJ12243.1 - 1.3 8.5 9.5 2.1 7.9 9.5 1.2 1 0 0 1 1 1 0 Spt20 family Myb_DNA-binding PF00249.31 OAJ12244.1 - 1.5e-10 41.1 0.2 8.4e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ12244.1 - 0.14 12.1 4.3 0.43 10.5 0.0 3.2 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 OAJ12244.1 - 0.14 12.5 0.5 16 5.8 0.1 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1899 PF08953.11 OAJ12245.1 - 1.6e-31 108.0 0.6 3.5e-31 106.9 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAJ12245.1 - 6e-18 64.5 1.0 5.1e-16 58.3 0.3 2.7 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 OAJ12245.1 - 7.3e-09 36.1 7.7 0.31 12.0 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12245.1 - 0.027 14.8 0.0 39 4.6 0.0 3.9 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ12245.1 - 0.031 13.2 0.0 4.7 6.1 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 OAJ12245.1 - 0.065 12.3 0.2 0.17 10.9 0.0 1.7 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain PRCC PF10253.9 OAJ12245.1 - 0.17 12.7 1.9 0.26 12.0 1.9 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TMF_DNA_bd PF12329.8 OAJ12245.1 - 0.23 11.5 1.1 0.41 10.7 1.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PIF1 PF05970.14 OAJ12246.1 - 0.00052 19.3 0.0 0.00068 18.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase CCDC92 PF14916.6 OAJ12258.1 - 0.12 12.2 0.2 0.54 10.1 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function DUF5102 PF17104.5 OAJ12259.1 - 6.8e-42 144.5 0.1 6.8e-42 144.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) zf-rbx1 PF12678.7 OAJ12260.1 - 1.2e-09 38.3 1.4 8e-09 35.7 0.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ12260.1 - 2.1e-09 37.6 6.3 6.9e-09 35.9 2.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ12260.1 - 9e-07 28.6 3.6 9e-07 28.6 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ12260.1 - 8.3e-06 25.5 5.9 0.00089 19.0 0.6 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 OAJ12260.1 - 3e-05 24.0 0.2 7.6e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ12260.1 - 0.00011 21.9 4.0 0.00012 21.9 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ12260.1 - 0.00031 20.5 0.8 0.00031 20.5 0.8 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAJ12260.1 - 0.00089 18.8 3.7 0.0037 16.9 2.6 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OAJ12260.1 - 0.00096 19.0 4.5 0.0012 18.7 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ12260.1 - 0.0012 18.9 0.7 0.0012 18.9 0.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ12260.1 - 0.0013 18.6 1.0 0.0013 18.6 1.0 1.6 2 0 0 2 2 1 1 zinc-RING finger domain FANCL_C PF11793.8 OAJ12260.1 - 0.13 12.5 1.7 0.68 10.1 0.8 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain AsnC_trans_reg PF01037.21 OAJ12260.1 - 0.19 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain zf-RING-like PF08746.11 OAJ12260.1 - 2.2 8.7 4.4 5.4 7.4 4.4 1.7 1 0 0 1 1 1 0 RING-like domain FAP PF07174.11 OAJ12260.1 - 3.6 7.0 22.4 1.9 7.9 19.1 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) RINGv PF12906.7 OAJ12260.1 - 4.3 7.5 7.2 0.39 10.9 2.3 1.8 2 0 0 2 2 1 0 RING-variant domain Rep_fac-A_C PF08646.10 OAJ12261.1 - 4.3e-56 188.7 1.9 5e-55 185.3 1.0 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAJ12261.1 - 8e-35 118.7 0.1 1.8e-34 117.5 0.1 1.6 1 0 0 1 1 1 1 Replication protein A OB domain Rep-A_N PF04057.12 OAJ12261.1 - 3e-25 88.2 0.0 6.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAJ12261.1 - 4.9e-12 45.7 0.3 3.8e-10 39.6 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 OAJ12261.1 - 0.0013 19.0 0.2 0.026 14.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 OAJ12261.1 - 0.15 11.7 0.0 2.4 7.8 0.0 2.4 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 SIS PF01380.22 OAJ12262.1 - 2.3e-64 215.1 0.2 4e-36 123.7 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAJ12262.1 - 2.9e-15 56.6 0.0 6.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ12262.1 - 2.6e-11 43.5 0.0 5.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAJ12262.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TTRAP PF14203.6 OAJ12262.1 - 0.057 13.4 0.6 0.36 10.8 0.1 2.5 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein SIS_2 PF13580.6 OAJ12262.1 - 0.08 13.0 0.0 0.98 9.4 0.0 2.7 3 1 1 4 4 4 0 SIS domain YoeB_toxin PF06769.14 OAJ12262.1 - 0.19 11.8 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system Aldedh PF00171.22 OAJ12263.1 - 2.5e-143 478.0 0.0 2.8e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CRCB PF02537.15 OAJ12264.1 - 4.4e-26 91.0 14.3 3.9e-16 59.1 2.5 2.7 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) DAGK_cat PF00781.24 OAJ12266.1 - 3e-13 49.5 0.0 5.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Surp PF01805.20 OAJ12275.1 - 1.4e-10 41.0 0.3 3.4e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 OAJ12275.1 - 1.4e-05 24.8 0.0 0.18 11.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 OAJ12275.1 - 0.035 14.9 0.0 0.077 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. CTK3 PF12243.8 OAJ12275.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 GatB_N PF02934.15 OAJ12277.1 - 2.7e-84 282.8 0.0 1e-79 267.8 0.0 2.8 3 0 0 3 3 3 2 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAJ12277.1 - 3.3e-27 95.2 0.0 1.2e-14 54.4 0.0 2.4 2 0 0 2 2 2 2 GatB domain AAA_19 PF13245.6 OAJ12278.1 - 2.9e-15 56.9 0.0 7.5e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAJ12278.1 - 3.9e-14 52.9 0.4 9e-11 41.8 0.7 2.6 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OAJ12278.1 - 9.3e-12 45.0 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 OAJ12278.1 - 1.8e-09 37.6 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 OAJ12278.1 - 6.6e-09 35.5 0.1 5.4e-08 32.5 0.1 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OAJ12278.1 - 1.4e-06 28.3 0.0 0.44 10.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 OAJ12278.1 - 0.0031 17.8 0.0 2.8 8.2 0.0 3.3 2 1 1 3 3 3 1 AAA domain PhoH PF02562.16 OAJ12278.1 - 0.19 11.2 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Gti1_Pac2 PF09729.9 OAJ12278.1 - 7.4 6.6 7.0 27 4.8 2.2 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4529 PF15032.6 OAJ12279.1 - 0.053 12.6 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) PMSR PF01625.21 OAJ12280.1 - 2.9e-57 193.1 0.8 3.6e-57 192.8 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DIPSY PF11763.8 OAJ12280.1 - 0.046 13.9 0.2 0.079 13.1 0.2 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal SURF4 PF02077.15 OAJ12281.1 - 5e-94 314.8 3.7 5.7e-94 314.6 3.7 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 OAJ12281.1 - 0.022 14.8 0.2 0.058 13.4 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5562) DoxX PF07681.12 OAJ12281.1 - 7.9 7.1 21.9 0.61 10.7 0.6 3.6 3 2 1 4 4 4 0 DoxX Citrate_bind PF16114.5 OAJ12282.1 - 2e-89 297.8 0.3 4.2e-89 296.8 0.1 1.6 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 OAJ12282.1 - 1.7e-19 70.1 0.1 1.2e-16 60.7 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OAJ12282.1 - 2.5e-14 53.3 0.1 6.7e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 OAJ12282.1 - 1.7e-13 51.1 0.0 6.2e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.10 OAJ12282.1 - 1.1e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OAJ12282.1 - 1.7e-05 24.6 0.0 0.00015 21.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 OAJ12282.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain LSM PF01423.22 OAJ12294.1 - 4.2e-22 77.6 0.2 4.8e-22 77.4 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ12294.1 - 0.014 15.5 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain JAB PF01398.21 OAJ12295.1 - 2.6e-15 56.4 0.0 1.2e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ12295.1 - 5.9e-14 52.4 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function NolB PF17398.2 OAJ12295.1 - 0.015 15.7 1.9 0.015 15.7 1.9 2.3 2 0 0 2 2 2 0 Nodulation protein NolB MRI PF15325.6 OAJ12295.1 - 0.64 11.1 5.3 1.2 10.3 0.0 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection Palm_thioest PF02089.15 OAJ12296.1 - 1e-05 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 OAJ12296.1 - 0.00033 20.0 0.0 0.0025 17.1 0.0 2.0 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 OAJ12296.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 OAJ12296.1 - 0.0033 17.1 0.0 0.16 11.6 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ12296.1 - 0.0054 17.4 0.1 0.016 15.8 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ12296.1 - 0.0077 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAJ12296.1 - 0.055 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.11 OAJ12296.1 - 0.15 11.4 0.0 0.42 9.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) TFIIF_beta PF02270.15 OAJ12297.1 - 7.6e-21 74.0 0.1 1.3e-20 73.3 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 OAJ12297.1 - 7.3e-16 59.1 0.0 2.1e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus DDE_Tnp_IS66_C PF13817.6 OAJ12297.1 - 0.14 12.4 0.3 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 IS66 C-terminal element Ribosomal_L16 PF00252.18 OAJ12299.1 - 7.6e-40 136.0 0.6 9.7e-40 135.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PX PF00787.24 OAJ12300.1 - 2.6e-11 43.5 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 PX domain ATG16 PF08614.11 OAJ12300.1 - 0.0025 18.1 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) INCA1 PF15142.6 OAJ12301.1 - 0.087 12.8 7.1 0.8 9.7 1.6 2.5 1 1 1 2 2 2 0 INCA1 LapA_dom PF06305.11 OAJ12301.1 - 0.74 9.7 0.0 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Bap31 PF05529.12 OAJ12302.1 - 1.2e-44 151.5 10.2 1.6e-44 151.0 10.2 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAJ12302.1 - 9.6e-06 25.5 3.7 1.7e-05 24.7 3.7 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DHR10 PF18595.1 OAJ12302.1 - 0.59 10.2 8.2 0.11 12.6 3.9 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SUR7 PF06687.12 OAJ12303.1 - 1.5e-15 57.4 14.2 1.9e-15 57.1 14.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family NAD_binding_10 PF13460.6 OAJ12304.1 - 1.6e-05 24.9 0.0 0.00027 20.9 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding BON PF04972.17 OAJ12304.1 - 0.26 11.6 1.2 13 6.2 0.0 3.1 3 0 0 3 3 3 0 BON domain Pkinase PF00069.25 OAJ12313.1 - 9.1e-56 189.1 0.0 5.3e-52 176.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12313.1 - 1.1e-32 113.4 0.0 1.2e-29 103.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ12313.1 - 5.9e-06 25.8 0.0 8.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ12313.1 - 1.5e-05 24.0 4.2 3.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAJ12313.1 - 0.0037 16.6 0.3 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ12313.1 - 0.004 17.1 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S4e PF00900.20 OAJ12313.1 - 0.22 11.4 0.1 0.45 10.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal family S4e SET PF00856.28 OAJ12314.1 - 1e-05 26.0 0.1 0.0088 16.4 0.0 2.7 2 1 1 3 3 3 2 SET domain SAF PF08666.12 OAJ12314.1 - 0.16 12.6 0.0 4.9 7.9 0.0 2.3 2 0 0 2 2 2 0 SAF domain Ribosomal_S3Ae PF01015.18 OAJ12315.1 - 1.2e-88 296.0 0.3 1.4e-88 295.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 OAJ12315.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region TipAS PF07739.13 OAJ12315.1 - 0.16 12.5 0.1 0.67 10.5 0.0 2.0 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain VanZ PF04892.12 OAJ12316.1 - 1.2e-07 32.4 0.7 1.8e-07 31.9 0.7 1.3 1 0 0 1 1 1 1 VanZ like family HECT PF00632.25 OAJ12317.1 - 6.6e-96 321.4 0.0 8.8e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAJ12317.1 - 1.3e-34 118.0 12.3 1.1e-11 44.6 2.4 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.30 OAJ12317.1 - 8.8e-19 67.7 0.1 2.3e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain Complex1_LYR PF05347.15 OAJ12318.1 - 0.0043 17.1 0.3 0.0091 16.0 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ12318.1 - 0.063 14.0 0.4 0.098 13.4 0.4 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Tctex-1 PF03645.13 OAJ12319.1 - 1.5e-11 44.5 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF4687 PF15747.5 OAJ12320.1 - 0.013 16.0 4.7 0.019 15.4 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) UPF0506 PF11703.8 OAJ12320.1 - 5.2 7.5 14.3 5.7 7.4 3.7 2.9 3 0 0 3 3 3 0 UPF0506 ParA PF10609.9 OAJ12321.1 - 1.8e-82 276.5 0.0 2.6e-57 194.1 0.0 2.1 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ12321.1 - 4e-05 23.7 1.6 0.00049 20.1 1.7 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAJ12321.1 - 0.0003 20.4 0.2 0.00064 19.3 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 OAJ12321.1 - 0.00053 19.9 0.1 0.0039 17.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 OAJ12321.1 - 0.0017 17.6 2.0 0.0057 15.9 0.3 2.4 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_16 PF13191.6 OAJ12321.1 - 0.0096 16.3 0.1 0.027 14.9 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_26 PF13500.6 OAJ12321.1 - 0.016 15.0 0.2 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAJ12321.1 - 0.095 12.6 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase IBR PF01485.21 OAJ12322.1 - 3.8e-16 59.1 36.9 3.6e-10 39.9 2.7 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 OAJ12322.1 - 8.9e-13 48.6 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OAJ12322.1 - 2.2e-07 31.1 3.9 2.2e-07 31.1 3.9 5.3 4 1 1 5 5 5 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ12322.1 - 1e-05 25.4 4.9 1e-05 25.4 4.9 4.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ12322.1 - 9.3e-05 22.3 6.9 9.3e-05 22.3 6.9 4.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ12322.1 - 0.00015 21.5 6.3 0.00015 21.5 6.3 4.5 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ12322.1 - 0.0007 19.3 4.9 0.0007 19.3 4.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ12322.1 - 0.0014 18.4 2.8 0.0014 18.4 2.8 5.4 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) LysR_substrate PF03466.20 OAJ12322.1 - 0.25 10.7 2.6 0.3 10.4 0.4 2.0 2 0 0 2 2 2 0 LysR substrate binding domain Citrate_synt PF00285.21 OAJ12331.1 - 4.1e-121 404.4 0.0 5.2e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain UQ_con PF00179.26 OAJ12332.1 - 1.5e-37 128.4 0.0 1.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GST_N_3 PF13417.6 OAJ12333.1 - 4.1e-13 49.5 0.0 7.5e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ12333.1 - 6.6e-10 39.2 0.1 1.5e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ12333.1 - 1.7e-05 24.8 0.1 5.5e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAJ12333.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Kinesin PF00225.23 OAJ12334.1 - 2.1e-97 326.0 6.2 3.5e-53 180.7 0.0 3.4 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ12334.1 - 1.1e-22 80.6 0.0 8e-21 74.5 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding FAM184 PF15665.5 OAJ12334.1 - 0.0018 18.1 34.1 0.0018 18.1 34.1 13.2 4 2 6 11 11 11 3 Family with sequence similarity 184, A and B Macoilin PF09726.9 OAJ12334.1 - 0.0018 16.9 7.3 0.0018 16.9 7.3 7.1 2 1 3 5 5 5 1 Macoilin family Spc7 PF08317.11 OAJ12334.1 - 0.0021 17.0 12.4 0.0021 17.0 12.4 12.0 4 2 9 13 13 13 5 Spc7 kinetochore protein HRDC PF00570.23 OAJ12334.1 - 0.0065 16.4 0.1 0.049 13.6 0.1 2.7 1 0 0 1 1 1 1 HRDC domain DNA_Packaging_2 PF11123.8 OAJ12334.1 - 3.1 8.1 6.0 3.3 8.0 0.1 4.1 3 1 1 4 4 4 0 DNA packaging protein AAA PF00004.29 OAJ12334.1 - 8.8 6.8 6.6 3 8.3 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) NOG1_N PF17835.1 OAJ12336.1 - 8.3e-45 152.6 0.3 8.3e-45 152.6 0.3 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAJ12336.1 - 8.4e-28 96.1 3.0 2.4e-27 94.7 3.0 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAJ12336.1 - 2.9e-27 94.2 0.1 5.3e-27 93.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAJ12336.1 - 2.1e-19 69.7 0.0 5.9e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ12336.1 - 5.1e-09 35.9 0.0 9.3e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ12336.1 - 0.00011 22.4 0.0 0.51 10.4 0.0 3.1 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 OAJ12336.1 - 0.0062 16.5 0.1 0.32 10.9 0.0 3.1 2 2 1 3 3 3 1 RsgA GTPase Roc PF08477.13 OAJ12336.1 - 0.028 14.6 0.0 0.2 11.9 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OAJ12336.1 - 0.036 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 OAJ12336.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Myc_N PF01056.18 OAJ12336.1 - 0.28 11.0 5.7 0.49 10.2 5.7 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.11 OAJ12336.1 - 1.6 6.7 5.7 2.5 6.1 5.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phos_pyr_kin PF08543.12 OAJ12344.1 - 1.1e-40 139.5 0.1 1.3e-23 83.7 0.0 3.2 3 0 0 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAJ12344.1 - 3.3e-21 76.1 0.2 2.5e-20 73.2 0.2 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 OAJ12344.1 - 0.0029 17.0 0.3 0.29 10.5 0.0 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family eIF-3c_N PF05470.12 OAJ12345.1 - 2.7e-180 600.6 4.2 2.7e-180 600.6 4.2 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAJ12345.1 - 5.7e-10 39.6 0.0 1.8e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 PCI domain CABIT PF12736.7 OAJ12345.1 - 0.016 14.5 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Cell-cycle sustaining, positive selection, DUF2408 PF10303.9 OAJ12345.1 - 0.021 15.4 0.6 18 5.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DDE_1 PF03184.19 OAJ12346.1 - 2.6e-50 170.5 0.1 5e-50 169.6 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ12346.1 - 9.3e-08 32.0 1.0 2.2e-07 30.8 0.2 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 OAJ12346.1 - 7.5e-07 28.8 0.2 2.6e-06 27.1 0.2 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain NdhN PF11909.8 OAJ12346.1 - 0.026 14.2 0.1 0.073 12.8 0.1 1.7 2 0 0 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N HTH_33 PF13592.6 OAJ12346.1 - 0.026 14.2 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix SDA1 PF05285.12 OAJ12346.1 - 0.6 9.5 9.9 1.3 8.3 9.9 1.5 1 0 0 1 1 1 0 SDA1 Adaptin_N PF01602.20 OAJ12348.1 - 2.2e-144 481.9 5.4 2.5e-144 481.7 5.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAJ12348.1 - 2.3e-25 89.1 1.4 4.3e-25 88.2 1.4 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAJ12348.1 - 2.1e-06 27.9 7.3 5.2e-05 23.3 0.5 3.4 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ12348.1 - 0.00024 21.5 3.7 3.3 8.2 0.2 5.1 5 1 2 7 7 7 2 HEAT repeats RIX1 PF08167.12 OAJ12348.1 - 0.0045 16.8 0.9 0.11 12.3 0.0 3.1 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 OAJ12348.1 - 0.038 14.3 0.7 81 3.9 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat NPCBM_assoc PF10633.9 OAJ12348.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Kinetochor_Ybp2 PF08568.10 OAJ12348.1 - 0.07 11.6 0.0 6.5 5.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin Peptidase_M73 PF12389.8 OAJ12348.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Phos_pyr_kin PF08543.12 OAJ12349.1 - 3.6e-25 88.8 0.2 3.1e-16 59.5 0.0 2.6 2 1 1 3 3 3 2 Phosphomethylpyrimidine kinase HK PF02110.15 OAJ12349.1 - 0.00013 21.5 0.7 0.047 13.1 0.0 2.7 2 1 1 3 3 3 2 Hydroxyethylthiazole kinase family PfkB PF00294.24 OAJ12349.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 pfkB family carbohydrate kinase DUF287 PF03384.14 OAJ12359.1 - 0.059 13.8 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Drosophila protein of unknown function, DUF287 LRR_4 PF12799.7 OAJ12359.1 - 0.15 12.6 5.1 8.2 7.0 0.5 5.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAJ12359.1 - 0.16 11.9 0.2 0.45 10.5 0.2 1.8 1 0 0 1 1 1 0 F-box-like Asp PF00026.23 OAJ12360.1 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ12360.1 - 0.00069 19.9 0.0 0.0028 17.9 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BRO1 PF03097.18 OAJ12372.1 - 1.1e-20 73.8 0.0 1.1e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 BRO1-like domain AhpC-TSA PF00578.21 OAJ12373.1 - 1.8e-06 27.9 0.0 6.2e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 OAJ12373.1 - 6.7e-05 22.6 0.0 8.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin SDA1 PF05285.12 OAJ12374.1 - 0.62 9.4 34.8 0.019 14.4 27.7 2.0 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 OAJ12374.1 - 9.1 4.3 34.7 21 3.2 34.7 1.5 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 OAJ12375.1 - 0.092 12.3 7.6 0.015 14.9 3.2 1.8 1 1 1 2 2 2 0 PPP4R2 BUD22 PF09073.10 OAJ12375.1 - 2.4 7.4 13.0 0.35 10.2 0.7 2.1 2 0 0 2 2 2 0 BUD22 TRAP_alpha PF03896.16 OAJ12375.1 - 6.1 5.9 6.3 1.3 8.2 1.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Bax1-I PF01027.20 OAJ12379.1 - 3.7e-46 157.6 21.1 4.3e-46 157.4 21.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3464 PF11947.8 OAJ12379.1 - 0.66 9.7 6.3 0.2 11.4 2.3 2.1 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 Pox_I5 PF04713.12 OAJ12379.1 - 2.1 8.5 9.3 0.61 10.2 0.2 2.8 2 1 0 2 2 2 0 Poxvirus protein I5 Nop53 PF07767.11 OAJ12380.1 - 3.9e-35 122.0 20.5 1.6e-34 120.0 20.5 1.9 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CFEM PF05730.11 OAJ12392.1 - 2.3e-08 34.0 8.1 4.6e-08 33.0 8.1 1.5 1 0 0 1 1 1 1 CFEM domain DUF1180 PF06679.12 OAJ12392.1 - 0.47 10.9 6.8 0.12 12.8 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) YqeY PF09424.10 OAJ12393.1 - 2.7e-25 89.1 1.5 3.3e-25 88.8 1.5 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF3365 PF11845.8 OAJ12393.1 - 0.013 15.8 0.3 0.016 15.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) DUF2880 PF11082.8 OAJ12393.1 - 1.1 9.6 4.6 0.28 11.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2880) Fcf1 PF04900.12 OAJ12394.1 - 1.9e-36 124.4 1.4 2.6e-36 124.0 1.4 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAJ12394.1 - 3.9e-11 43.3 0.0 5.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Tannase PF07519.11 OAJ12395.1 - 2.8e-74 250.7 0.0 1.8e-64 218.4 0.0 2.3 2 1 0 2 2 2 2 Tannase and feruloyl esterase UreD PF01774.17 OAJ12396.1 - 1.5e-59 201.5 0.1 2.3e-59 200.9 0.1 1.3 1 0 0 1 1 1 1 UreD urease accessory protein Pet100 PF09803.9 OAJ12397.1 - 5.1e-25 87.8 0.0 6.7e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Pet100 Med1 PF10744.9 OAJ12397.1 - 0.018 14.1 0.2 0.022 13.8 0.2 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Hydrolase_6 PF13344.6 OAJ12398.1 - 1.4e-29 102.2 0.0 3.1e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ12398.1 - 4.5e-18 65.1 0.1 8e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAJ12398.1 - 1.2e-07 32.0 0.7 0.00017 21.7 0.1 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ12398.1 - 1.4e-07 32.0 0.0 5.5e-07 30.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OAJ12398.1 - 0.00094 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.10 OAJ12398.1 - 0.074 12.7 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase CLN3 PF02487.17 OAJ12399.1 - 3.1e-113 378.8 0.0 3.9e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 CLN3 protein DUF4611 PF15387.6 OAJ12399.1 - 5.1 7.4 8.6 18 5.6 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ATP-synt_D PF01813.17 OAJ12400.1 - 1.3e-72 243.7 4.1 1.9e-72 243.3 4.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Paf1 PF03985.13 OAJ12400.1 - 0.025 13.6 3.1 0.038 13.0 3.1 1.2 1 0 0 1 1 1 0 Paf1 DUF4366 PF14283.6 OAJ12400.1 - 0.069 13.2 0.7 0.15 12.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4746 PF15928.5 OAJ12400.1 - 0.67 9.3 4.8 1 8.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PTPRCAP PF15713.5 OAJ12400.1 - 3.8 7.8 11.9 3.3 8.0 8.7 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated WD40 PF00400.32 OAJ12401.1 - 2.9e-08 34.2 13.3 0.031 15.2 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12401.1 - 0.0062 16.8 0.0 3.6 8.0 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CFEM PF05730.11 OAJ12402.1 - 0.00064 19.8 4.7 0.00064 19.8 4.7 2.0 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.11 OAJ12403.1 - 8.9e-07 28.9 16.2 1.7e-06 28.0 16.2 1.5 1 1 0 1 1 1 1 CFEM domain TIL PF01826.17 OAJ12403.1 - 1.1 9.5 12.6 0.32 11.3 9.8 1.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain p450 PF00067.22 OAJ12412.1 - 9.1e-67 225.8 0.0 1.4e-66 225.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2680 PF10925.8 OAJ12412.1 - 0.038 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF4386 PF14329.6 OAJ12412.1 - 0.11 12.3 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) TNFR_16_TM PF18422.1 OAJ12412.1 - 1.7 8.7 3.1 3.7 7.6 3.1 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain GMC_oxred_N PF00732.19 OAJ12413.1 - 1.2e-59 202.2 0.0 1.6e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ12413.1 - 6.4e-28 98.1 0.0 1.4e-27 97.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAJ12413.1 - 4.3e-05 23.2 0.1 9.5e-05 22.1 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ12413.1 - 0.00013 22.2 0.0 0.00032 20.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAJ12413.1 - 0.00082 18.5 0.4 0.0012 17.9 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAJ12413.1 - 0.00091 18.4 1.4 0.0018 17.4 1.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ12413.1 - 0.0016 17.8 0.7 0.016 14.5 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ12413.1 - 0.0031 16.8 0.0 0.0081 15.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ12413.1 - 0.013 14.3 0.3 0.022 13.5 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAJ12413.1 - 0.12 11.6 0.2 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 Thi4 family HSP70 PF00012.20 OAJ12414.1 - 1.1e-48 165.9 9.5 1.7e-44 152.0 0.0 4.1 2 2 1 3 3 3 2 Hsp70 protein Prefoldin PF02996.17 OAJ12414.1 - 0.17 11.8 1.8 0.87 9.5 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit p450 PF00067.22 OAJ12415.1 - 4.7e-58 197.1 0.0 1.7e-57 195.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 WD40 PF00400.32 OAJ12415.1 - 2.7e-08 34.3 1.3 0.034 15.0 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12415.1 - 0.0047 17.2 0.0 4.9 7.5 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ12415.1 - 0.086 11.8 0.0 0.45 9.4 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 OAJ12417.1 - 3.5e-75 252.9 21.9 4e-75 252.8 21.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ12417.1 - 1.2 7.2 34.1 1.6 6.9 34.1 1.0 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 OAJ12417.1 - 1.7 8.1 16.0 2.5 7.6 16.0 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein DNA_pol_phi PF04931.13 OAJ12417.1 - 4.4 5.3 38.4 5.4 5.0 38.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 OAJ12417.1 - 6.7 6.6 27.0 8.6 6.2 27.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 OAJ12418.1 - 4.8e-58 195.7 0.5 5.9e-58 195.4 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like NmrA PF05368.13 OAJ12430.1 - 4.5e-25 88.6 0.0 5.7e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ12430.1 - 1.8e-14 54.1 0.0 3.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAJ12430.1 - 2e-06 28.1 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAJ12430.1 - 0.0072 16.4 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 OAJ12430.1 - 0.03 13.8 0.0 0.076 12.5 0.0 1.7 1 1 1 2 2 2 0 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 OAJ12430.1 - 0.04 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 OAJ12430.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAJ12430.1 - 0.077 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 OAJ12430.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HAMP PF00672.25 OAJ12435.1 - 3.6 8.0 5.6 2 8.9 0.4 3.3 4 0 0 4 4 4 0 HAMP domain SH3_9 PF14604.6 OAJ12436.1 - 4e-10 39.4 0.0 6.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ12436.1 - 6.1e-08 32.2 0.0 9.9e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ12436.1 - 2.8e-06 26.9 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain adh_short_C2 PF13561.6 OAJ12437.1 - 4.6e-52 176.9 0.1 5.9e-52 176.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ12437.1 - 6.2e-48 162.9 0.5 7.5e-48 162.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ12437.1 - 3.3e-09 36.9 0.2 5e-09 36.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ12437.1 - 0.0097 15.4 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family V_ATPase_I PF01496.19 OAJ12445.1 - 0 1030.0 0.0 0 1029.8 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 OAJ12445.1 - 0.033 14.1 0.3 0.1 12.6 0.3 1.7 2 0 0 2 2 2 0 Prefoldin subunit HAP1_N PF04849.13 OAJ12445.1 - 0.041 13.1 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Hrs_helical PF12210.8 OAJ12445.1 - 0.12 12.9 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SlyX PF04102.12 OAJ12445.1 - 0.17 12.5 0.9 13 6.5 0.3 3.1 3 0 0 3 3 3 0 SlyX GAS PF13851.6 OAJ12445.1 - 0.2 11.0 0.7 0.37 10.1 0.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FTA4 PF13093.6 OAJ12445.1 - 0.98 9.3 3.6 1.1 9.1 2.1 1.9 2 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 JAB PF01398.21 OAJ12446.1 - 1.6e-14 53.9 0.0 2.8e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OAJ12446.1 - 2.1e-07 30.7 0.4 4.6e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.11 OAJ12446.1 - 4e-05 23.8 0.0 7.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain UIM PF02809.20 OAJ12446.1 - 0.017 15.0 2.1 0.041 13.8 2.1 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif NRBF2_MIT PF17169.4 OAJ12446.1 - 0.035 14.3 0.4 0.088 13.0 0.4 1.6 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Gaa1 PF04114.14 OAJ12447.1 - 1.9e-58 198.7 0.0 2.3e-50 172.0 0.0 2.4 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component Helicase_C PF00271.31 OAJ12448.1 - 2.9e-23 82.3 0.0 4e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Steroid_dh PF02544.16 OAJ12449.1 - 1.5e-34 119.2 1.1 2.6e-34 118.4 1.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 OAJ12449.1 - 3e-07 30.1 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 OAJ12449.1 - 1.9e-06 27.6 0.6 3.9e-06 26.5 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAJ12449.1 - 0.0061 16.9 1.7 0.0096 16.3 0.4 1.9 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 OAJ12449.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.5 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2407 PF10302.9 OAJ12449.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DEAD PF00270.29 OAJ12450.1 - 2.4e-46 157.7 0.0 3.8e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ12450.1 - 2.6e-06 27.6 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.8 OAJ12450.1 - 0.0054 17.2 0.6 0.0054 17.2 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) MFAP1 PF06991.11 OAJ12450.1 - 0.019 14.8 2.9 0.036 13.9 2.9 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing CALM_bind PF16025.5 OAJ12450.1 - 0.15 12.6 2.3 0.42 11.1 2.3 1.7 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding CMS1 PF14617.6 OAJ12450.1 - 0.16 11.3 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit APH PF01636.23 OAJ12451.1 - 6.3e-39 134.3 0.0 9.6e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ12451.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 OAJ12451.1 - 0.003 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAJ12451.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 OAJ12452.1 - 7.1e-38 130.9 0.0 1.3e-37 130.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 OAJ12452.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 OAJ12452.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 OAJ12452.1 - 0.12 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) MINDY_DUB PF04424.13 OAJ12461.1 - 1.1e-22 80.3 0.0 7.1e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 MINDY deubiquitinase MFS_1 PF07690.16 OAJ12462.1 - 8.4e-45 153.2 51.0 8.4e-45 153.2 51.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ12462.1 - 6.9e-16 57.8 12.2 6.9e-16 57.8 12.2 2.5 2 1 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ12462.1 - 7.6e-14 51.4 4.0 7.6e-14 51.4 4.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAJ12462.1 - 0.0031 15.9 3.0 0.0031 15.9 3.0 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family TPR_1 PF00515.28 OAJ12463.1 - 6.9e-10 38.3 0.7 4.3e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12463.1 - 3.9e-08 32.8 0.4 0.00054 19.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ12463.1 - 0.0011 18.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ12463.1 - 0.0017 18.6 0.1 1.2 9.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12463.1 - 0.0063 17.2 0.4 0.56 11.2 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ12463.1 - 0.0067 16.7 0.2 0.22 11.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAJ12463.1 - 0.058 13.5 0.4 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 OAJ12463.1 - 0.077 13.2 1.0 0.54 10.5 0.2 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OAJ12463.1 - 0.083 12.6 0.1 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 OAJ12463.1 - 0.13 12.6 1.1 0.67 10.3 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltransf_33 PF10017.9 OAJ12464.1 - 2.4e-63 214.1 0.0 9.9e-52 176.0 0.0 2.2 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAJ12464.1 - 6.5e-18 65.2 3.3 7.3e-18 65.1 0.1 2.3 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAJ12464.1 - 3.3e-05 24.4 2.3 5.1e-05 23.8 0.9 2.1 2 0 0 2 2 2 1 DinB superfamily DUF2076 PF09849.9 OAJ12465.1 - 1.6e-06 28.3 22.2 3.2e-06 27.4 22.2 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAJ12465.1 - 1.2e-05 25.3 4.1 1.9e-05 24.6 4.1 1.3 1 0 0 1 1 1 1 CHCH domain RskA PF10099.9 OAJ12465.1 - 0.013 15.8 7.9 0.016 15.5 7.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CX9C PF16860.5 OAJ12465.1 - 0.015 15.3 1.0 0.028 14.4 1.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-CCHC_3 PF13917.6 OAJ12466.1 - 1.2e-08 34.7 2.1 1.2e-08 34.7 2.1 2.2 2 0 0 2 2 2 1 Zinc knuckle CDC14 PF08045.11 OAJ12466.1 - 6.6e-07 28.7 3.9 0.014 14.5 0.1 3.0 2 1 0 2 2 2 2 Cell division control protein 14, SIN component Aa_trans PF01490.18 OAJ12467.1 - 5.9e-82 275.6 33.4 7.2e-82 275.3 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PTPRCAP PF15713.5 OAJ12467.1 - 0.0002 21.6 1.3 0.0002 21.6 1.3 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated Ctr PF04145.15 OAJ12467.1 - 0.008 16.8 0.0 0.33 11.6 0.0 2.7 2 0 0 2 2 2 1 Ctr copper transporter family Sporozoite_P67 PF05642.11 OAJ12467.1 - 0.068 11.3 1.6 0.096 10.8 1.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PC_rep PF01851.22 OAJ12467.1 - 0.15 12.6 0.0 4.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Proteasome/cyclosome repeat CDC45 PF02724.14 OAJ12467.1 - 1.3 7.2 3.5 1.9 6.7 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ12467.1 - 2.5 7.3 6.2 3.8 6.8 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ12467.1 - 5.3 5.0 5.3 7.6 4.5 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ12467.1 - 7.1 4.7 5.4 9.3 4.3 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.7 OAJ12477.1 - 0.00042 20.2 2.2 0.00068 19.5 0.3 2.4 2 0 0 2 2 2 1 F-box-like BrnA_antitoxin PF14384.6 OAJ12477.1 - 0.087 13.3 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Sec1 PF00995.23 OAJ12478.1 - 7.7e-122 408.4 0.0 9.2e-122 408.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Ribosomal_L23 PF00276.20 OAJ12479.1 - 2.3e-06 27.9 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 AAA PF00004.29 OAJ12481.1 - 1.4e-59 200.2 0.0 5.9e-45 152.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ12481.1 - 2.3e-08 34.6 0.7 0.0086 16.5 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 OAJ12481.1 - 1.7e-07 30.9 1.2 0.027 14.3 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_18 PF13238.6 OAJ12481.1 - 1e-06 29.3 0.0 0.039 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OAJ12481.1 - 0.00013 22.0 0.0 0.037 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ12481.1 - 0.00018 21.3 0.0 0.0057 16.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAJ12481.1 - 0.00037 20.5 0.0 0.92 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ12481.1 - 0.0004 20.7 0.4 0.032 14.5 0.1 3.0 2 1 1 3 3 2 1 AAA domain TsaE PF02367.17 OAJ12481.1 - 0.0011 18.9 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAJ12481.1 - 0.0014 18.9 0.0 0.61 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ12481.1 - 0.0015 17.8 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 OAJ12481.1 - 0.0017 18.1 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 OAJ12481.1 - 0.0023 17.4 0.1 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 OAJ12481.1 - 0.0026 17.9 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ12481.1 - 0.0037 17.4 0.0 0.48 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ12481.1 - 0.0053 16.4 0.1 0.025 14.2 0.1 1.9 1 1 1 2 2 2 1 AAA domain CDC48_2 PF02933.17 OAJ12481.1 - 0.0057 16.4 0.1 0.23 11.3 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 OAJ12481.1 - 0.0062 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAJ12481.1 - 0.0068 16.5 0.0 0.02 15.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 OAJ12481.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 OAJ12481.1 - 0.012 14.8 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 OAJ12481.1 - 0.012 15.3 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Mg_chelatase PF01078.21 OAJ12481.1 - 0.015 14.7 0.4 0.06 12.7 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAJ12481.1 - 0.021 15.2 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 OAJ12481.1 - 0.027 14.0 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_17 PF13207.6 OAJ12481.1 - 0.047 14.1 0.0 18 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 OAJ12481.1 - 0.056 13.3 0.0 0.85 9.5 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ12481.1 - 0.064 13.2 0.3 4.4 7.2 0.1 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAJ12481.1 - 0.084 12.6 0.0 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ12481.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.22 OAJ12481.1 - 0.17 12.0 0.0 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 OAJ12481.1 - 0.22 10.7 0.0 6.7 5.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_29 PF13555.6 OAJ12481.1 - 0.24 11.2 0.8 21 5.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4692 PF15763.5 OAJ12481.1 - 3.3 8.2 5.2 12 6.3 5.2 1.9 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TAP42 PF04177.12 OAJ12482.1 - 1.6e-66 224.7 0.0 2.8e-66 223.8 0.0 1.4 1 1 0 1 1 1 1 TAP42-like family CAP_N PF01213.19 OAJ12482.1 - 0.76 9.2 5.9 0.25 10.8 2.3 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NAD_binding_10 PF13460.6 OAJ12483.1 - 1.3e-25 90.4 0.0 1.8e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ12483.1 - 0.00087 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAJ12483.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Phage_tail_APC PF16778.5 OAJ12483.1 - 0.013 15.3 0.2 8.4 6.3 0.2 2.9 2 1 1 3 3 3 0 Phage tail assembly chaperone protein NAD_binding_4 PF07993.12 OAJ12483.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Ldh_1_N PF00056.23 OAJ12484.1 - 5.6e-47 159.4 0.4 8e-47 158.9 0.4 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAJ12484.1 - 4.7e-45 153.5 0.0 7.6e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 OAJ12484.1 - 2.4e-06 26.8 0.0 4.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAJ12484.1 - 0.00087 19.2 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 OAJ12484.1 - 0.0049 16.2 0.3 0.079 12.3 0.3 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 OAJ12484.1 - 0.0056 16.2 0.2 0.37 10.3 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase Dimer_Tnp_hAT PF05699.14 OAJ12493.1 - 7.5e-08 32.1 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CENP-B_dimeris PF09026.10 OAJ12494.1 - 0.2 12.1 4.4 1.1 9.7 5.3 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DLIC PF05783.11 OAJ12505.1 - 2 7.2 6.8 2.3 6.9 6.8 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF1713 PF08213.11 OAJ12509.1 - 3e-10 39.8 25.0 4.4e-10 39.3 25.0 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Cation_efflux PF01545.21 OAJ12510.1 - 1.8e-47 161.7 13.7 1.8e-47 161.7 13.7 2.7 3 0 0 3 3 3 1 Cation efflux family CorA PF01544.18 OAJ12511.1 - 8.8e-09 35.1 1.9 1.6e-08 34.2 1.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 OAJ12511.1 - 0.33 8.8 0.9 0.6 7.9 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-U PF13097.6 OAJ12511.1 - 4.2 7.3 7.6 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit PAT1 PF09770.9 OAJ12511.1 - 5.7 5.1 7.0 8.1 4.6 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GDP_Man_Dehyd PF16363.5 OAJ12512.1 - 5.7e-43 147.6 0.0 7.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ12512.1 - 4.8e-41 140.8 0.0 5.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ12512.1 - 2.4e-12 46.4 0.0 5.5e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ12512.1 - 5e-07 29.1 0.3 7.8e-07 28.5 0.1 1.3 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAJ12512.1 - 4e-05 22.9 0.0 0.00034 19.9 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAJ12512.1 - 7.7e-05 22.0 0.0 0.0002 20.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OAJ12512.1 - 0.00014 21.8 0.2 0.00043 20.2 0.2 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ12512.1 - 0.00025 21.0 0.0 0.0015 18.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAJ12512.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase Ribonuc_L-PSP PF01042.21 OAJ12512.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP F-box PF00646.33 OAJ12521.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAJ12521.1 - 0.032 14.1 0.1 0.046 13.6 0.1 1.4 1 1 0 1 1 1 0 F-box Drf_FH1 PF06346.12 OAJ12535.1 - 0.015 15.0 8.4 0.015 15.0 8.4 1.8 2 0 0 2 2 2 0 Formin Homology Region 1 Ras PF00071.22 OAJ12537.1 - 2.4e-57 193.0 0.2 2.8e-57 192.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ12537.1 - 6e-20 71.7 0.0 9e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ12537.1 - 3.6e-08 33.1 0.0 4.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ12537.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ12537.1 - 0.00043 20.2 0.0 0.31 10.9 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ12537.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ12537.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B CbiA PF01656.23 OAJ12537.1 - 0.16 12.0 0.3 1.6 8.8 0.3 2.1 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AMP-binding PF00501.28 OAJ12539.1 - 1.5e-98 330.2 0.1 1.8e-98 330.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ12539.1 - 1.2e-25 90.3 1.6 1.7e-25 89.8 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 OAJ12539.1 - 6.7e-17 61.2 3.6 6.8e-17 61.1 0.3 2.6 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus NAD_binding_10 PF13460.6 OAJ12539.1 - 0.092 12.6 0.2 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 OAJ12540.1 - 1.4e-73 247.5 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12540.1 - 3.2e-29 102.0 0.0 3.9e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ12540.1 - 7.3e-08 32.1 0.0 9.7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ12540.1 - 3.4e-05 22.8 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ12540.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NtA PF03146.15 OAJ12540.1 - 0.042 13.7 0.1 0.12 12.2 0.1 1.7 2 0 0 2 2 2 0 Agrin NtA domain APH PF01636.23 OAJ12540.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CDC37_M PF08565.11 OAJ12542.1 - 1.2e-18 67.2 0.0 2.4e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAJ12542.1 - 5.8e-18 64.9 0.2 1.5e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 Cdc37 C terminal domain Med11 PF10280.9 OAJ12543.1 - 3.1e-11 43.9 0.7 5.3e-11 43.1 0.7 1.4 1 1 0 1 1 1 1 Mediator complex protein Med29 PF11568.8 OAJ12543.1 - 0.014 15.6 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 CwsA PF10814.8 OAJ12543.1 - 0.28 11.4 3.7 0.29 11.3 0.2 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA LSM14 PF12701.7 OAJ12544.1 - 8e-26 90.0 0.0 1.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAJ12544.1 - 9.2e-07 29.7 0.2 9.2e-07 29.7 0.2 2.7 2 2 0 2 2 2 1 FDF domain SM-ATX PF14438.6 OAJ12544.1 - 0.00017 21.6 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 OAJ12544.1 - 2.8 7.8 21.7 4.2 7.3 21.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC37_N PF03234.14 OAJ12545.1 - 2.3e-35 122.3 4.1 2.3e-35 122.3 4.1 2.6 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding Peptidase_S30 PF01577.16 OAJ12545.1 - 0.085 12.5 3.8 0.047 13.3 1.2 1.7 2 0 0 2 2 2 0 Potyvirus P1 protease DFRP_C PF16543.5 OAJ12545.1 - 0.14 12.7 0.3 0.14 12.7 0.3 2.6 2 1 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 APG6_N PF17675.1 OAJ12546.1 - 0.36 11.4 6.3 0.59 10.7 6.3 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GTA_holin_3TM PF11351.8 OAJ12558.1 - 0.62 10.6 3.7 0.9 10.1 3.7 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release RVT_2 PF07727.14 OAJ12559.1 - 8.4e-15 55.1 0.0 9.4e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_Tnp_Tc5 PF03221.16 OAJ12560.1 - 1.6e-05 24.8 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAJ12560.1 - 0.0016 18.1 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HhH-GPD PF00730.25 OAJ12560.1 - 0.024 15.1 0.0 3.9 8.0 0.0 2.3 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein KAR9 PF08580.10 OAJ12561.1 - 0.38 9.2 6.7 0.44 9.0 6.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIA PF03153.13 OAJ12562.1 - 0.012 15.6 1.4 0.013 15.5 1.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit U79_P34 PF03064.16 OAJ12562.1 - 0.016 14.6 3.1 0.023 14.1 3.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DNA_pol_phi PF04931.13 OAJ12562.1 - 0.12 10.5 9.8 0.15 10.2 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAJ12562.1 - 0.33 9.2 3.9 0.42 8.9 3.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ12562.1 - 0.35 10.5 3.2 0.64 9.7 3.2 1.4 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 OAJ12562.1 - 0.37 9.3 7.2 0.5 8.9 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 OAJ12562.1 - 0.58 9.2 13.4 0.8 8.8 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tom22 PF04281.13 OAJ12562.1 - 1.4 8.7 7.8 2.3 8.0 7.8 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NDC10_II PF16787.5 OAJ12563.1 - 8.2e-36 123.6 0.0 9.4e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 OrsD PF12013.8 OAJ12574.1 - 5.8e-12 46.1 0.2 1.3e-11 44.9 0.2 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D SpoIIIAC PF06686.11 OAJ12574.1 - 0.19 11.9 0.1 0.33 11.2 0.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family Dimer_Tnp_hAT PF05699.14 OAJ12576.1 - 7e-09 35.4 0.0 2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HhH-GPD PF00730.25 OAJ12582.1 - 1.9e-15 57.2 0.0 5e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 OAJ12582.1 - 1.2e-14 54.2 0.0 3.4e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 OAJ12582.1 - 0.00035 20.3 0.1 0.001 18.9 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif PG_binding_2 PF08823.11 OAJ12582.1 - 0.06 13.7 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WW PF00397.26 OAJ12583.1 - 3.4e-09 36.6 2.6 0.0017 18.4 0.2 3.0 3 0 0 3 3 3 2 WW domain FAD_binding_1 PF00667.20 OAJ12584.1 - 4e-29 101.8 0.0 6.2e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAJ12584.1 - 1e-27 97.1 0.0 2.5e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 OAJ12584.1 - 7e-11 42.7 0.0 1.7e-10 41.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAJ12584.1 - 0.043 14.0 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_3 PF12641.7 OAJ12584.1 - 0.056 13.1 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 Flavodoxin domain Formyl_trans_N PF00551.19 OAJ12585.1 - 2.3e-31 108.9 0.0 3.2e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAJ12585.1 - 5.6e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAJ12585.1 - 0.00015 21.7 0.2 0.00045 20.1 0.0 1.9 2 0 0 2 2 2 1 ACT domain MDM10 PF12519.8 OAJ12586.1 - 1e-84 285.1 0.0 1.1e-55 189.4 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 OAJ12586.1 - 0.00014 21.4 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic porin TIP120 PF08623.10 OAJ12587.1 - 5.6e-55 185.7 7.7 1.5e-53 181.0 0.2 4.3 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAJ12587.1 - 1.6e-15 57.2 28.1 0.13 12.7 0.1 9.8 6 3 3 10 10 10 6 HEAT repeats HEAT_EZ PF13513.6 OAJ12587.1 - 3.1e-12 46.7 32.9 0.74 10.4 0.2 12.9 10 2 3 13 13 13 5 HEAT-like repeat HEAT PF02985.22 OAJ12587.1 - 5.6e-12 44.8 22.5 2.1 8.8 0.0 12.9 14 1 2 16 16 12 3 HEAT repeat Adaptin_N PF01602.20 OAJ12587.1 - 3.4e-09 35.8 23.4 6.7e-05 21.6 0.9 6.2 2 2 3 5 5 5 3 Adaptin N terminal region Cnd1 PF12717.7 OAJ12587.1 - 3.4e-08 33.7 13.2 0.42 10.6 0.2 7.3 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 OAJ12587.1 - 2.5e-07 30.6 2.8 1.2 9.1 0.0 7.2 7 2 0 7 7 7 1 UME (NUC010) domain RTP1_C1 PF10363.9 OAJ12587.1 - 8.9e-06 25.9 10.7 0.98 9.6 0.0 8.6 8 2 1 9 9 9 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 OAJ12587.1 - 1.3e-05 24.9 0.1 1.6 8.2 0.0 5.1 6 0 0 6 6 5 2 Tti2 family Vac14_Fab1_bd PF12755.7 OAJ12587.1 - 5e-05 23.8 0.1 22 5.7 0.0 7.9 8 2 2 10 10 8 0 Vacuolar 14 Fab1-binding region DCB PF16213.5 OAJ12587.1 - 0.00024 20.8 2.5 4 7.1 0.0 5.0 4 1 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 MMS19_N PF14500.6 OAJ12587.1 - 0.00036 20.2 3.2 0.26 10.9 0.0 6.0 6 2 2 8 8 8 1 Dos2-interacting transcription regulator of RNA-Pol-II SIL1 PF16782.5 OAJ12587.1 - 0.00086 18.6 2.2 0.55 9.4 0.1 3.4 2 1 1 3 3 3 2 Nucleotide exchange factor SIL1 CLASP_N PF12348.8 OAJ12587.1 - 0.0011 18.5 4.7 0.54 9.8 0.1 5.5 5 1 1 6 6 6 1 CLASP N terminal DUF3361 PF11841.8 OAJ12587.1 - 0.0078 16.2 5.3 0.28 11.1 0.0 5.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3361) DUF5578 PF17741.1 OAJ12587.1 - 0.016 14.6 1.9 1.3 8.3 0.1 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5578) Ribosomal_S6 PF01250.17 OAJ12587.1 - 0.016 15.4 0.1 2.2 8.6 0.0 3.5 3 0 0 3 3 3 0 Ribosomal protein S6 Sigma70_ner PF04546.13 OAJ12587.1 - 0.018 14.9 7.5 0.18 11.6 2.1 2.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RIX1 PF08167.12 OAJ12587.1 - 0.02 14.7 0.1 0.02 14.7 0.1 6.7 7 3 0 7 7 6 0 rRNA processing/ribosome biogenesis BTV_NS2 PF04514.12 OAJ12587.1 - 0.031 13.1 2.3 0.053 12.3 2.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 U3snoRNP10 PF12397.8 OAJ12587.1 - 0.068 13.5 11.0 0.38 11.1 0.2 5.8 6 0 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 Cnd3 PF12719.7 OAJ12587.1 - 0.082 12.1 3.4 1.9 7.6 0.0 4.4 6 0 0 6 6 6 0 Nuclear condensing complex subunits, C-term domain RNA_pol_3_Rpc31 PF11705.8 OAJ12587.1 - 0.84 9.9 8.9 1.5 9.0 8.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 OAJ12587.1 - 4.2 5.8 11.1 2 6.9 7.9 2.2 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Septin PF00735.18 OAJ12588.1 - 1.3e-107 359.3 0.4 1.8e-107 358.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAJ12588.1 - 4.5e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ12588.1 - 0.00028 20.5 0.1 0.0093 15.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ12588.1 - 0.00085 19.4 3.8 0.11 12.5 0.1 3.1 2 1 1 3 3 3 1 Dynamin family AAA_22 PF13401.6 OAJ12588.1 - 0.0021 18.3 0.7 0.008 16.5 0.0 2.2 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ12588.1 - 0.0035 17.2 3.9 0.0092 15.9 0.6 2.9 3 1 0 3 3 2 1 RsgA GTPase AIG1 PF04548.16 OAJ12588.1 - 0.004 16.5 0.0 0.0075 15.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 OAJ12588.1 - 0.0042 16.5 0.2 0.0098 15.3 0.2 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_33 PF13671.6 OAJ12588.1 - 0.0062 16.7 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAJ12588.1 - 0.0076 16.5 1.1 0.1 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain IIGP PF05049.13 OAJ12588.1 - 0.0086 15.2 0.1 0.02 13.9 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_19 PF13245.6 OAJ12588.1 - 0.011 16.0 0.0 0.3 11.4 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ12588.1 - 0.011 16.1 0.9 0.028 14.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OAJ12588.1 - 0.022 15.2 0.0 0.068 13.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 OAJ12588.1 - 0.027 14.7 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ12588.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ12588.1 - 0.047 14.2 6.4 2.5 8.5 1.9 2.2 2 1 0 2 2 2 0 AAA domain Ras PF00071.22 OAJ12588.1 - 0.068 12.8 0.7 0.47 10.1 0.0 2.5 3 0 0 3 3 3 0 Ras family RNA_helicase PF00910.22 OAJ12588.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 OAJ12588.1 - 0.12 12.9 1.1 0.73 10.4 0.0 2.7 2 1 2 4 4 4 0 AAA domain Pox_A32 PF04665.12 OAJ12588.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 OAJ12588.1 - 0.14 11.9 0.4 1.5 8.6 0.4 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 OAJ12588.1 - 0.95 9.5 5.4 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAJ12589.1 - 4.4e-16 59.0 0.1 1.1e-13 51.3 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ12589.1 - 3.2e-07 30.0 0.2 7.6e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 OAJ12589.1 - 5.1e-05 22.9 0.0 0.0027 17.3 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ12589.1 - 7.1e-05 22.9 0.6 0.13 12.4 0.2 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 OAJ12589.1 - 0.00015 21.7 0.5 0.11 12.4 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase SRP-alpha_N PF04086.13 OAJ12589.1 - 0.0062 16.5 12.7 0.012 15.6 12.7 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Dysbindin PF04440.16 OAJ12589.1 - 0.087 13.0 1.0 18 5.5 0.0 3.0 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) Herpes_UL56 PF04534.12 OAJ12589.1 - 0.48 9.9 8.3 0.81 9.1 0.2 2.4 1 1 1 2 2 2 0 Herpesvirus UL56 protein ORC6 PF05460.13 OAJ12589.1 - 0.54 9.5 7.8 0.97 8.6 7.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NUDE_C PF04880.13 OAJ12589.1 - 0.73 10.3 8.5 2.6 8.5 8.5 1.9 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PHA_synth_III_E PF09712.10 OAJ12597.1 - 0.056 12.5 0.8 0.22 10.5 0.3 1.9 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) GP38 PF05268.11 OAJ12597.1 - 1 9.0 28.7 0.23 11.1 25.0 1.7 1 1 1 2 2 2 0 Phage tail fibre adhesin Gp38 PCNA_C PF02747.15 OAJ12599.1 - 3.3e-43 146.9 0.1 6.1e-23 81.4 0.2 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 OAJ12599.1 - 6.7e-41 139.0 2.1 1.4e-40 137.9 0.2 2.4 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.13 OAJ12599.1 - 0.0013 18.3 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 Rad9 LRS4 PF10422.9 OAJ12599.1 - 0.012 15.2 1.0 0.019 14.5 1.0 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF3246 PF11596.8 OAJ12599.1 - 0.035 13.5 0.4 0.057 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Myc_N PF01056.18 OAJ12599.1 - 0.25 11.2 2.0 0.35 10.7 2.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PAC1 PF16094.5 OAJ12599.1 - 8.9 5.4 5.5 13 4.8 5.5 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 HIG_1_N PF04588.13 OAJ12601.1 - 6e-17 61.6 0.2 8.5e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4786 PF16027.5 OAJ12601.1 - 0.11 13.1 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) Abhydrolase_6 PF12697.7 OAJ12602.1 - 2.7e-17 64.1 0.1 4.1e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ12602.1 - 4.6e-15 56.0 0.3 4.9e-12 46.1 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ12602.1 - 4.3e-13 49.1 0.2 7e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAJ12602.1 - 5.9e-07 29.4 0.2 2e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAJ12602.1 - 0.0048 17.0 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 OAJ12602.1 - 0.0078 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase PF07224.11 OAJ12602.1 - 0.031 13.3 0.1 0.045 12.8 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF676 PF05057.14 OAJ12602.1 - 0.044 13.3 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 OAJ12602.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.28 OAJ12602.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.15 OAJ12602.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ABC_membrane PF00664.23 OAJ12603.1 - 1.3e-12 48.0 3.1 2.6e-12 47.0 2.4 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region TMEM154 PF15102.6 OAJ12603.1 - 0.0012 18.8 0.1 0.0041 17.0 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family AAA_29 PF13555.6 OAJ12603.1 - 0.0012 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 OAJ12603.1 - 0.0024 18.0 0.1 0.011 15.8 0.1 2.0 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 OAJ12603.1 - 0.0043 17.6 0.1 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAJ12603.1 - 0.0055 17.2 0.0 0.0099 16.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_ATPase PF09818.9 OAJ12603.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SMC_N PF02463.19 OAJ12603.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain p450 PF00067.22 OAJ12614.1 - 6.3e-22 77.9 0.0 1.5e-21 76.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DEAD_assoc PF08494.11 OAJ12614.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 DEAD/H associated GDI PF00996.18 OAJ12615.1 - 1.5e-206 686.1 0.0 1.8e-206 685.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAJ12615.1 - 0.021 15.0 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_hydro_18 PF00704.28 OAJ12616.1 - 8.3e-59 199.8 0.0 1.1e-58 199.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 OAJ12616.1 - 0.071 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family p450 PF00067.22 OAJ12617.1 - 1.1e-21 77.2 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 OAJ12618.1 - 2.3e-51 174.5 0.0 5.7e-51 173.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ12618.1 - 2.8e-29 102.7 0.0 1.6e-24 87.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Pyrid_oxidase_2 PF13883.6 OAJ12620.1 - 1.1e-24 87.3 0.0 1.7e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Amidase PF01425.21 OAJ12621.1 - 3.7e-95 319.5 0.0 4.4e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Amidase QWRF PF04484.12 OAJ12622.1 - 0.12 12.1 3.0 0.16 11.7 3.0 1.3 1 0 0 1 1 1 0 QWRF family YL1 PF05764.13 OAJ12622.1 - 1.4 9.0 3.5 2.4 8.2 3.5 1.3 1 1 0 1 1 1 0 YL1 nuclear protein RP-C_C PF11800.8 OAJ12623.1 - 9.8 6.2 13.3 6.8 6.7 0.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region SKG6 PF08693.10 OAJ12627.1 - 0.052 13.0 0.1 0.052 13.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Syndecan PF01034.20 OAJ12627.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain DUF572 PF04502.13 OAJ12628.1 - 1.3e-63 215.7 0.4 1.4e-63 215.5 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DEC-1_N PF04625.13 OAJ12628.1 - 0.033 13.2 1.5 0.044 12.8 1.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF866 PF05907.13 OAJ12628.1 - 0.054 13.4 0.4 0.092 12.7 0.3 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Glyco_hydro_63 PF03200.16 OAJ12629.1 - 5.1e-09 35.4 4.0 2e-07 30.1 0.3 4.1 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Methyltransf_16 PF10294.9 OAJ12630.1 - 7.3e-10 38.8 0.1 0.00031 20.5 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Mucin PF01456.17 OAJ12630.1 - 0.12 12.3 3.8 7.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein gag_pre-integrs PF13976.6 OAJ12631.1 - 2e-06 27.6 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Ank_2 PF12796.7 OAJ12633.1 - 5.2e-11 43.0 0.0 7.6e-06 26.4 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ12633.1 - 6.3e-11 42.6 0.0 2.4e-06 28.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ12633.1 - 1.2e-08 35.1 0.1 0.28 11.6 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ12633.1 - 3.7e-07 29.9 0.0 0.064 13.8 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ12633.1 - 0.00054 20.3 0.0 1.6 9.3 0.1 3.5 3 1 0 3 3 3 1 Ankyrin repeat CobT PF06213.12 OAJ12633.1 - 0.25 10.7 9.4 0.39 10.1 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.6 OAJ12633.1 - 2 8.8 9.1 3.8 8.0 9.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ12633.1 - 2.1 7.6 13.2 3 7.1 13.2 1.1 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 OAJ12633.1 - 2.7 7.0 4.2 3.3 6.7 4.2 1.1 1 0 0 1 1 1 0 Pes-10 Pentapeptide PF00805.22 OAJ12634.1 - 2.5e-21 75.0 6.3 7.2e-08 31.9 0.2 6.0 5 1 0 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 OAJ12634.1 - 5.2e-13 49.0 0.0 0.00022 21.3 0.0 4.2 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Rhomboid PF01694.22 OAJ12641.1 - 5.2e-25 88.2 7.5 8.1e-25 87.6 7.5 1.3 1 0 0 1 1 1 1 Rhomboid family TBP PF00352.21 OAJ12642.1 - 1.5e-67 223.5 0.2 1.7e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAJ12642.1 - 1.1e-05 25.4 0.0 0.21 11.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAJ12642.1 - 0.068 13.0 0.2 0.63 9.9 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Na_Ca_ex PF01699.24 OAJ12643.1 - 2.8e-25 89.0 20.1 2.2e-13 50.4 9.8 2.8 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3446 PF11928.8 OAJ12643.1 - 0.16 12.3 0.2 0.16 12.3 0.2 3.7 5 0 0 5 5 5 0 Early growth response N-terminal domain GRA6 PF05084.13 OAJ12643.1 - 0.33 10.9 3.9 11 5.9 0.1 2.9 3 1 0 3 3 3 0 Granule antigen protein (GRA6) UBN_AB PF14075.6 OAJ12644.1 - 2.7e-30 105.7 0.0 2.7e-30 105.7 0.0 3.2 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 OAJ12644.1 - 1.6e-10 40.8 0.0 1.6e-10 40.8 0.0 3.0 2 1 0 2 2 2 1 HPC2 and ubinuclein domain DUF4207 PF13904.6 OAJ12644.1 - 0.0051 16.5 0.2 0.0051 16.5 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) Dickkopf_N PF04706.12 OAJ12645.1 - 7.9 7.0 11.1 20 5.8 7.1 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF711 PF05167.12 OAJ12646.1 - 0.031 13.2 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) NMO PF03060.15 OAJ12647.1 - 9e-46 156.8 1.1 3.6e-44 151.5 1.1 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAJ12647.1 - 5.8e-09 35.4 0.5 0.00074 18.6 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAJ12647.1 - 0.0023 17.0 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAJ12647.1 - 0.039 13.4 0.1 0.083 12.3 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein CENP-B_dimeris PF09026.10 OAJ12648.1 - 0.12 12.8 8.5 0.77 10.2 0.8 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ACOX PF01756.19 OAJ12649.1 - 1.5e-43 148.5 0.4 6.6e-43 146.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAJ12649.1 - 1.3e-22 80.7 0.3 2.9e-22 79.5 0.3 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAJ12649.1 - 5.7e-09 36.1 0.0 9.8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ12649.1 - 5.5e-05 23.4 0.3 0.0029 17.8 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aldo_ket_red PF00248.21 OAJ12650.1 - 8.7e-50 169.6 0.0 5.6e-49 166.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family SPRY PF00622.28 OAJ12656.1 - 1.4e-20 73.6 0.2 3e-20 72.5 0.2 1.6 1 0 0 1 1 1 1 SPRY domain BAR PF03114.18 OAJ12657.1 - 2.4e-39 135.4 1.6 3.4e-39 134.9 1.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 OAJ12657.1 - 3.7e-16 58.5 0.0 6.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ12657.1 - 5.2e-12 45.4 0.0 8.5e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ12657.1 - 4.9e-11 42.1 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.11 OAJ12657.1 - 0.014 14.8 0.3 0.019 14.4 0.3 1.3 1 0 0 1 1 1 0 FAM92 protein DUF3104 PF11302.8 OAJ12657.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Hormone_3 PF00159.18 OAJ12657.1 - 0.13 12.4 2.8 0.16 12.1 1.4 2.0 2 0 0 2 2 2 0 Pancreatic hormone peptide CBP_BcsO PF17037.5 OAJ12657.1 - 0.84 9.8 10.5 1.4 9.0 10.5 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO DNA_pol_B PF00136.21 OAJ12659.1 - 9.2e-116 387.3 0.0 1.3e-115 386.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OAJ12659.1 - 4.3e-55 186.3 0.1 7.4e-55 185.6 0.1 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAJ12659.1 - 2.1e-33 115.9 0.0 4.3e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAJ12659.1 - 4e-23 81.3 6.8 1.2e-22 79.7 6.8 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF155 PF02582.14 OAJ12659.1 - 0.16 12.1 0.4 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised ACR, YagE family COG1723 YL1 PF05764.13 OAJ12659.1 - 9.6 6.2 14.4 0.66 10.1 3.5 2.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF1769 PF08588.10 OAJ12660.1 - 2.7e-22 78.7 0.1 4.8e-22 77.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cys_Met_Meta_PP PF01053.20 OAJ12661.1 - 1.4e-24 86.3 0.0 6e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ12661.1 - 0.00085 18.6 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Tetraspanin PF00335.20 OAJ12662.1 - 1.9e-06 27.7 0.6 4.6e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 Tetraspanin family MARVEL PF01284.23 OAJ12662.1 - 0.0031 17.6 8.6 0.013 15.6 8.2 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF2207 PF09972.9 OAJ12662.1 - 0.079 11.7 1.7 0.21 10.3 1.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Trp_oprn_chp PF09534.10 OAJ12662.1 - 0.12 12.2 1.6 0.35 10.6 0.8 1.9 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rad51 PF08423.11 OAJ12674.1 - 2.6e-128 426.7 0.1 3e-128 426.4 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAJ12674.1 - 2.9e-11 43.3 0.0 4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OAJ12674.1 - 8.7e-10 38.5 0.1 1.2e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OAJ12674.1 - 7.8e-07 28.7 0.0 1.4e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OAJ12674.1 - 6.5e-06 26.7 0.2 1.7e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 OAJ12674.1 - 0.0028 17.0 0.1 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 OAJ12674.1 - 0.007 15.5 1.0 0.035 13.3 0.6 1.9 1 1 1 2 2 2 1 PAXNEB protein HHH PF00633.23 OAJ12674.1 - 0.036 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif ssDNA_TraI_N PF18272.1 OAJ12674.1 - 0.073 13.1 0.2 0.18 11.9 0.2 1.6 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain CAF1C_H4-bd PF12265.8 OAJ12675.1 - 3.5e-28 97.6 0.1 1e-27 96.2 0.1 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ12675.1 - 6.7e-26 90.0 9.5 3e-05 24.7 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12675.1 - 2.2e-06 27.9 1.2 0.015 15.6 0.1 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans PF04082.18 OAJ12676.1 - 9.1e-06 24.9 0.1 1.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ12676.1 - 0.00075 19.6 14.8 0.0013 18.8 14.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S7e PF01251.18 OAJ12677.1 - 1.8e-80 269.1 0.0 2e-80 268.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Thr_synth_N PF14821.6 OAJ12678.1 - 3e-26 91.4 0.0 1.4e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 OAJ12678.1 - 8.2e-19 68.1 0.3 6.9e-18 65.1 0.3 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CC2-LZ PF16516.5 OAJ12678.1 - 0.0046 17.3 0.2 0.0096 16.3 0.2 1.5 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Clat_adaptor_s PF01217.20 OAJ12679.1 - 8.8e-44 148.9 0.4 7.3e-34 116.7 0.3 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DUF1180 PF06679.12 OAJ12679.1 - 0.11 12.9 1.5 0.19 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Chorismate_bind PF00425.18 OAJ12680.1 - 3.6e-73 246.3 0.0 6.6e-73 245.4 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 OAJ12680.1 - 1.8e-26 93.1 0.0 1.9e-15 57.2 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAJ12680.1 - 8.8e-16 58.4 0.0 8.5e-15 55.2 0.0 2.5 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAJ12680.1 - 0.00045 20.0 0.2 0.08 12.7 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 zf-C3HC4_3 PF13920.6 OAJ12681.1 - 0.034 14.0 6.6 0.064 13.1 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dabb PF07876.12 OAJ12682.1 - 2e-21 76.4 0.2 2.3e-21 76.2 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Luteo_coat PF00894.18 OAJ12682.1 - 0.052 13.4 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Luteovirus coat protein PRMT5 PF05185.16 OAJ12691.1 - 6e-59 198.8 0.0 9.6e-59 198.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 OAJ12691.1 - 9e-59 198.8 0.0 1.5e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 OAJ12691.1 - 3.7e-50 170.2 0.0 5.5e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 OAJ12691.1 - 0.00016 22.3 0.0 0.00051 20.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ12691.1 - 0.00094 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ceramidase PF05875.12 OAJ12692.1 - 4.5e-71 239.4 4.5 5.1e-71 239.2 4.5 1.0 1 0 0 1 1 1 1 Ceramidase HMG_box PF00505.19 OAJ12693.1 - 2.3e-15 56.7 1.4 3.7e-15 56.1 0.3 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ12693.1 - 6.5e-12 45.9 0.2 1.5e-11 44.8 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain TFIIA PF03153.13 OAJ12693.1 - 0.015 15.3 17.3 0.026 14.6 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 OAJ12693.1 - 0.029 13.2 2.1 0.051 12.4 2.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2385 PF09539.10 OAJ12693.1 - 1.4 9.5 3.8 5.5 7.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) EPL1 PF10513.9 OAJ12693.1 - 5.3 7.4 9.7 27 5.1 5.1 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM76 PF16046.5 OAJ12693.1 - 6.1 6.1 11.7 0.58 9.5 6.5 1.8 2 0 0 2 2 2 0 FAM76 protein DASH_Dad4 PF08650.10 OAJ12694.1 - 7.3e-25 86.7 0.0 1.1e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 OAJ12694.1 - 0.015 15.4 0.2 0.02 15.1 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 AIM5 PF17050.5 OAJ12696.1 - 0.0004 21.1 7.8 0.0038 18.0 4.0 2.7 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF349 PF03993.12 OAJ12696.1 - 0.088 13.1 0.8 0.088 13.1 0.8 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF883 PF05957.13 OAJ12696.1 - 1.9 9.2 9.7 0.11 13.2 1.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2924 PF11149.8 OAJ12696.1 - 2.2 8.7 5.6 1.3 9.4 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Mito_carr PF00153.27 OAJ12697.1 - 7.8e-66 218.1 2.4 2e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTAD PF03704.17 OAJ12697.1 - 0.061 13.8 0.4 0.1 13.0 0.4 1.4 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Virul_fac_BrkB PF03631.15 OAJ12698.1 - 6.3e-05 22.7 3.9 0.00021 21.0 3.3 1.9 1 1 0 1 1 1 1 Virulence factor BrkB RTA1 PF04479.13 OAJ12698.1 - 0.0001 22.0 1.5 0.00027 20.6 1.5 1.7 1 1 0 1 1 1 1 RTA1 like protein DUF373 PF04123.13 OAJ12698.1 - 0.11 11.9 0.6 0.19 11.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) PMP22_Claudin PF00822.20 OAJ12698.1 - 0.19 11.6 0.8 0.55 10.1 0.2 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Cation_efflux PF01545.21 OAJ12699.1 - 2.6e-49 167.7 15.4 7.8e-49 166.1 15.4 1.7 1 1 0 1 1 1 1 Cation efflux family ADH_N PF08240.12 OAJ12700.1 - 6.7e-31 106.4 0.2 1.4e-30 105.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ12700.1 - 5.9e-25 87.8 0.1 9.4e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ12700.1 - 4.6e-07 29.5 0.0 7.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAJ12700.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 OAJ12700.1 - 0.0014 18.6 0.5 0.0034 17.3 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Sacchrp_dh_NADP PF03435.18 OAJ12700.1 - 0.0017 18.6 0.2 0.0033 17.7 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Methyltransf_25 PF13649.6 OAJ12700.1 - 0.0018 18.9 0.0 0.0045 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 OAJ12700.1 - 0.0018 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 OAJ12700.1 - 0.0047 18.0 0.0 0.008 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ssu72 PF04722.13 OAJ12701.1 - 1.3e-85 285.8 0.0 1.5e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LIP PF03583.14 OAJ12708.1 - 1.9e-48 165.3 0.1 2.8e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ12708.1 - 0.0038 16.5 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF591 PF04569.14 OAJ12708.1 - 0.085 12.9 0.1 21 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function DOCK_N PF16172.5 OAJ12710.1 - 3.1e-115 385.1 0.0 7.4e-115 383.9 0.0 1.7 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 OAJ12710.1 - 9.5e-71 239.0 3.1 5.1e-70 236.6 0.0 2.8 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 OAJ12710.1 - 1.1e-50 172.2 0.0 3.1e-50 170.7 0.0 1.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4690 PF15756.5 OAJ12711.1 - 0.66 10.6 9.1 0.12 13.0 3.0 3.0 2 1 0 3 3 3 0 Small Novel Rich in Cartilage Zip PF02535.22 OAJ12711.1 - 9.4 5.3 7.4 0.4 9.8 1.4 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter CK_II_beta PF01214.18 OAJ12712.1 - 1.5e-80 269.3 0.0 1.9e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FAD_binding_2 PF00890.24 OAJ12713.1 - 4.6e-82 276.3 0.5 7e-82 275.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAJ12713.1 - 6.2e-22 77.5 0.0 1.8e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 OAJ12713.1 - 1.5e-13 51.1 1.4 6.5e-13 49.0 1.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ12713.1 - 2.6e-10 40.4 0.9 2.3e-09 37.3 0.4 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ12713.1 - 1.1e-07 31.4 0.2 4.1e-07 29.5 0.1 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ12713.1 - 2.4e-07 30.5 0.3 2.4e-07 30.5 0.3 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 OAJ12713.1 - 1.4e-06 27.6 0.9 0.0033 16.6 0.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAJ12713.1 - 2.4e-06 27.0 0.0 0.0078 15.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ12713.1 - 2.4e-06 26.5 1.4 9.7e-05 21.2 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 OAJ12713.1 - 7.1e-06 25.5 0.5 1.5e-05 24.5 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAJ12713.1 - 0.00013 21.3 0.3 0.0034 16.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 OAJ12713.1 - 0.00018 21.0 0.4 0.0019 17.6 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAJ12713.1 - 0.00049 19.4 0.1 0.00049 19.4 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAJ12713.1 - 0.0016 19.0 0.4 0.013 16.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ12713.1 - 0.024 14.6 0.1 1 9.4 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAJ12713.1 - 0.044 14.2 0.1 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding GDI PF00996.18 OAJ12713.1 - 0.066 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.12 OAJ12713.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Aldo_ket_red PF00248.21 OAJ12720.1 - 8.1e-45 153.3 0.0 4.7e-43 147.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 OAJ12721.1 - 6.5e-34 117.2 0.0 1.1e-32 113.2 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ12721.1 - 2.3e-25 89.2 0.0 3.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ12721.1 - 1.1e-06 28.3 0.0 4.3e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAJ12721.1 - 0.00033 21.0 0.1 0.0011 19.2 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 OAJ12721.1 - 0.021 14.2 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MULE PF10551.9 OAJ12723.1 - 0.00015 22.1 0.0 0.00092 19.6 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain AhpC-TSA PF00578.21 OAJ12724.1 - 3.1e-19 69.1 0.0 4.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ12724.1 - 7.1e-14 51.8 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin Aa_trans PF01490.18 OAJ12725.1 - 1.6e-86 290.6 6.0 2e-86 290.3 6.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Lipase_3 PF01764.25 OAJ12726.1 - 6.3e-22 78.0 0.0 1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ12726.1 - 4.4e-05 22.9 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ12726.1 - 0.0032 18.1 0.1 0.0064 17.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RHH_8 PF17723.1 OAJ12726.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family E1-E2_ATPase PF00122.20 OAJ12733.1 - 3.2e-20 72.4 0.0 6.5e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ12733.1 - 1.4e-17 64.7 0.1 1.1e-10 42.1 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ12733.1 - 0.004 16.9 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ12733.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 OAJ12733.1 - 0.035 13.6 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase LAL_C2 PF18603.1 OAJ12733.1 - 1.5 9.0 5.6 0.23 11.6 0.5 2.4 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Dynamin_M PF01031.20 OAJ12734.1 - 3.9e-101 338.0 0.0 1.1e-100 336.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ12734.1 - 1.7e-55 187.6 0.1 4.6e-55 186.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAJ12734.1 - 6.9e-30 103.1 5.2 6.9e-30 103.1 5.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAJ12734.1 - 0.00018 21.5 0.2 0.00095 19.2 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ12734.1 - 0.086 13.2 0.0 0.48 10.8 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 OAJ12734.1 - 0.13 11.9 0.3 16 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Chorismate_bind PF00425.18 OAJ12735.1 - 1.6e-89 299.9 0.1 2e-89 299.5 0.1 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAJ12735.1 - 1.6e-24 86.7 0.0 1e-23 84.1 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.8 OAJ12736.1 - 2.2e-43 148.7 6.7 2.2e-43 148.7 6.7 2.1 1 1 1 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAJ12736.1 - 1e-34 118.3 1.5 1.8e-17 63.1 0.1 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAJ12736.1 - 0.17 11.5 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Erg28 PF03694.13 OAJ12737.1 - 1.4e-43 147.7 3.1 1.8e-43 147.4 3.1 1.1 1 0 0 1 1 1 1 Erg28 like protein DHHC PF01529.20 OAJ12738.1 - 1.4e-30 106.2 8.5 1.4e-30 106.2 8.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 OAJ12738.1 - 3.4 7.5 13.4 0.82 9.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) TMEM214 PF10151.9 OAJ12741.1 - 3.4 6.0 6.1 5.3 5.4 6.1 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MOR2-PAG1_N PF14222.6 OAJ12746.1 - 2.7e-106 356.7 0.0 4.9e-106 355.9 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAJ12746.1 - 8.5e-72 242.1 1.7 8.5e-72 242.1 1.7 3.1 3 1 1 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAJ12746.1 - 5.7e-21 74.0 0.5 6.5e-08 30.7 0.0 4.9 5 0 0 5 5 5 4 Cell morphogenesis central region Glyco_transf_22 PF03901.17 OAJ12747.1 - 3.3e-27 95.8 9.6 4.3e-27 95.4 9.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family adh_short_C2 PF13561.6 OAJ12748.1 - 2.2e-36 125.6 0.1 3.1e-36 125.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ12748.1 - 3.4e-30 104.9 0.0 4.7e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ12748.1 - 2.7e-06 27.4 0.1 4.2e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAJ12748.1 - 0.0019 17.6 0.3 0.0058 16.0 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OAJ12748.1 - 0.0045 17.4 0.1 0.0093 16.4 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAJ12748.1 - 0.02 14.8 0.6 0.038 13.9 0.7 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ12748.1 - 0.042 13.9 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ12748.1 - 0.048 13.9 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N PF00107.26 OAJ12748.1 - 0.082 12.9 0.4 0.24 11.4 0.2 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase RRM_1 PF00076.22 OAJ12748.1 - 0.1 12.4 0.2 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sof1 PF04158.14 OAJ12750.1 - 1.6e-27 95.5 13.4 2.5e-27 95.0 13.4 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAJ12750.1 - 2.1e-27 94.8 6.8 1.1e-05 26.0 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12750.1 - 2.3e-07 31.0 0.0 1.8 9.0 0.0 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ12750.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 OAJ12750.1 - 0.13 12.3 0.0 5.2 7.1 0.0 3.2 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Fungal_trans PF04082.18 OAJ12751.1 - 3.8e-25 88.4 0.0 1.6e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ12751.1 - 6.7e-08 32.5 6.6 1.2e-07 31.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 OAJ12762.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) TBCC PF07986.12 OAJ12764.1 - 3e-14 52.8 2.1 7.1e-14 51.6 1.8 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 OAJ12764.1 - 0.39 10.3 2.0 0.34 10.5 0.5 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal NLE PF08154.12 OAJ12765.1 - 2.2e-15 56.9 0.0 3.8e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 OAJ12765.1 - 9.6e-14 51.6 26.3 0.016 16.1 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12765.1 - 0.018 15.3 0.0 3.6 7.9 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PhoLip_ATPase_C PF16212.5 OAJ12766.1 - 6.5e-50 170.2 22.2 6.5e-50 170.2 22.2 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ12766.1 - 7.7e-18 63.9 3.2 2.2e-17 62.5 3.2 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ12766.1 - 1.9e-13 51.2 3.6 1.3e-10 41.9 3.6 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ12766.1 - 2.1e-11 43.7 7.3 2.9e-05 23.7 0.2 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ12766.1 - 1.9e-10 40.6 0.0 1.3e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ12766.1 - 0.0014 18.5 0.1 0.0035 17.1 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.25 OAJ12767.1 - 1e-13 51.6 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ12767.1 - 1.3e-10 41.6 0.1 1.8e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ12767.1 - 1.3e-09 38.0 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ12767.1 - 0.00039 21.1 0.0 0.00051 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ12767.1 - 0.004 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ12767.1 - 0.056 13.5 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UcrQ PF02939.16 OAJ12768.1 - 2.1e-26 91.6 3.8 2.8e-26 91.2 3.8 1.2 1 0 0 1 1 1 1 UcrQ family Torus PF16131.5 OAJ12769.1 - 1.1e-36 125.8 0.2 3.2e-36 124.3 0.2 1.8 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 OAJ12769.1 - 9.7e-09 34.9 0.0 2.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAJ12769.1 - 0.00018 21.5 0.5 0.0003 20.7 0.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAJ12769.1 - 0.00019 21.2 1.6 0.00035 20.4 1.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAJ12769.1 - 0.0032 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 OAJ12769.1 - 0.13 12.1 2.5 0.22 11.4 2.5 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ12769.1 - 1 9.9 2.7 1.7 9.3 2.7 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Prenyltrans PF00432.21 OAJ12770.1 - 1.9e-47 158.6 2.1 7e-11 41.7 0.0 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat PIP5K PF01504.18 OAJ12771.1 - 1.9e-99 332.3 0.1 9.6e-98 326.8 0.0 2.6 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Arm PF00514.23 OAJ12772.1 - 3.1e-73 239.8 28.0 8.4e-13 47.9 0.1 12.0 11 1 2 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ12772.1 - 3.9e-19 68.7 10.8 8.5e-05 23.0 0.1 7.6 5 2 2 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 OAJ12772.1 - 2.8e-18 66.1 6.7 0.0063 16.9 0.0 6.8 3 2 2 6 6 6 5 HEAT repeats HEAT PF02985.22 OAJ12772.1 - 9.7e-16 56.5 12.2 0.87 10.0 0.0 9.1 8 0 0 8 8 8 5 HEAT repeat Adaptin_N PF01602.20 OAJ12772.1 - 1.1e-10 40.8 11.7 1.3e-08 33.9 0.9 2.3 1 1 0 2 2 2 2 Adaptin N terminal region KAP PF05804.12 OAJ12772.1 - 5.3e-10 38.1 2.3 9e-10 37.3 2.3 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 OAJ12772.1 - 4.9e-09 35.9 9.1 0.0016 17.8 4.9 4.5 1 1 0 3 3 3 3 V-ATPase subunit H Arm_2 PF04826.13 OAJ12772.1 - 5.5e-09 35.9 10.1 1.8e-05 24.4 3.3 2.8 1 1 1 2 2 2 2 Armadillo-like Cnd1 PF12717.7 OAJ12772.1 - 2.7e-07 30.8 7.4 0.045 13.8 0.1 4.5 2 2 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAJ12772.1 - 3.2e-06 27.2 12.1 0.0018 18.2 0.2 4.2 3 1 1 5 5 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 OAJ12772.1 - 9e-05 22.0 8.4 0.39 10.1 1.1 4.2 2 1 2 4 4 4 2 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 OAJ12772.1 - 0.00013 22.1 4.2 8.3 6.6 0.0 5.0 2 1 3 5 5 5 1 V-ATPase subunit H IFRD PF05004.13 OAJ12772.1 - 0.0079 15.3 6.0 0.92 8.5 0.1 4.2 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 OAJ12772.1 - 0.019 15.6 10.0 1.1e+02 3.9 0.0 7.6 9 0 0 9 9 8 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ12772.1 - 0.032 14.8 0.1 6.7 7.4 0.0 3.4 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region YqfD PF06898.11 OAJ12772.1 - 0.036 12.9 0.0 0.082 11.7 0.0 1.5 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD RTP1_C1 PF10363.9 OAJ12772.1 - 0.049 13.8 2.1 16 5.7 0.0 4.0 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 OAJ12772.1 - 0.11 12.5 5.8 6.5 6.7 0.1 3.8 3 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.9 OAJ12772.1 - 0.24 11.5 4.4 0.93 9.6 0.1 3.6 3 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF1751 PF08551.10 OAJ12779.1 - 2.5e-25 88.9 7.7 4.6e-25 88.1 7.7 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OAJ12779.1 - 0.00046 20.2 9.6 0.0013 18.7 9.6 1.8 1 1 0 1 1 1 1 Rhomboid family THOC2_N PF16134.5 OAJ12779.1 - 0.33 9.5 2.0 0.47 9.0 2.0 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus MSP1_C PF07462.11 OAJ12779.1 - 0.92 8.1 3.7 1.3 7.6 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1752 PF08550.10 OAJ12780.1 - 3.7e-11 42.6 4.2 6.9e-11 41.8 4.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RdRP PF05183.12 OAJ12781.1 - 1.8e-166 555.2 0.0 2.3e-166 554.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase UTP15_C PF09384.10 OAJ12782.1 - 2e-35 121.6 0.0 4e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAJ12782.1 - 2.6e-22 78.7 0.7 3.8e-05 24.4 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAJ12782.1 - 0.0041 16.1 0.0 0.48 9.3 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MutL PF13941.6 OAJ12782.1 - 0.054 12.1 1.0 0.084 11.5 1.0 1.2 1 0 0 1 1 1 0 MutL protein Nup160 PF11715.8 OAJ12782.1 - 0.074 11.7 0.9 1.3 7.6 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Isochorismatase PF00857.20 OAJ12783.1 - 3.3e-05 24.1 0.0 9.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family LIDHydrolase PF10230.9 OAJ12784.1 - 3.4e-46 158.0 0.0 1.6e-45 155.8 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAJ12784.1 - 2.9e-05 24.8 1.1 5.4e-05 23.9 1.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ12784.1 - 0.00015 21.1 0.1 0.00036 19.9 0.1 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ12784.1 - 0.072 12.7 0.1 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ12784.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAJ12784.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ANTH PF07651.16 OAJ12786.1 - 6e-70 235.4 0.1 6e-70 235.4 0.1 2.7 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 OAJ12786.1 - 1.9e-56 190.6 10.9 1.9e-56 190.6 10.9 5.5 5 1 1 6 6 6 2 I/LWEQ domain ENTH PF01417.20 OAJ12786.1 - 3.5e-05 23.8 1.5 0.00045 20.3 0.0 3.5 3 1 0 3 3 3 1 ENTH domain Autophagy_N PF03986.13 OAJ12797.1 - 1.7e-42 144.6 0.0 3e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OAJ12797.1 - 1.6e-18 67.0 0.1 2.8e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OAJ12797.1 - 3.9e-11 42.2 0.4 6.9e-11 41.5 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal eIF3_subunit PF08597.10 OAJ12797.1 - 2.8 7.8 6.1 0.78 9.6 0.1 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit C2 PF00168.30 OAJ12798.1 - 2.2e-70 233.5 0.1 4.3e-20 71.9 0.0 4.5 4 0 0 4 4 4 4 C2 domain MMM1 PF10296.9 OAJ12798.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 CC2D2AN-C2 PF15625.6 OAJ12798.1 - 0.015 15.0 0.0 3.2 7.5 0.0 3.6 4 0 0 4 4 4 0 CC2D2A N-terminal C2 domain NT-C2 PF10358.9 OAJ12798.1 - 0.032 14.0 0.0 0.6 9.8 0.0 3.0 4 0 0 4 4 4 0 N-terminal C2 in EEIG1 and EHBP1 proteins RasGAP PF00616.19 OAJ12799.1 - 3.1e-47 161.0 0.3 3.1e-46 157.7 0.0 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ12799.1 - 8.1e-47 158.8 4.4 8.1e-47 158.8 4.4 2.4 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 OAJ12799.1 - 8.3e-24 81.1 26.2 0.0025 17.4 0.1 10.0 9 0 0 9 9 9 9 IQ calmodulin-binding motif CH PF00307.31 OAJ12799.1 - 1.3e-16 60.7 0.0 3.7e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain ATPase_2 PF01637.18 OAJ12800.1 - 6.7e-07 29.4 0.1 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OAJ12800.1 - 0.0004 20.8 2.9 0.00067 20.1 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ12800.1 - 0.0025 18.1 0.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ12800.1 - 0.0091 15.7 0.6 0.052 13.3 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 OAJ12800.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region UDG PF03167.19 OAJ12801.1 - 6e-18 65.3 0.2 2.2e-09 37.5 0.0 2.7 3 0 0 3 3 3 2 Uracil DNA glycosylase superfamily DUF3235 PF11574.8 OAJ12801.1 - 7 7.6 0.0 7 7.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) adh_short PF00106.25 OAJ12802.1 - 4.3e-19 68.7 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12802.1 - 1.6e-11 44.2 0.0 3.4e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF5436 PF17504.2 OAJ12802.1 - 0.027 14.8 0.2 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5436) Xan_ur_permease PF00860.20 OAJ12803.1 - 1.2e-25 90.1 29.2 5.5e-24 84.6 29.2 2.2 1 1 0 1 1 1 1 Permease family DUF2015 PF09435.10 OAJ12812.1 - 1.6e-25 89.1 0.0 2.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) VHS PF00790.19 OAJ12813.1 - 1e-32 112.9 0.1 2.1e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAJ12813.1 - 6.4e-15 54.5 0.1 1.1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ12813.1 - 9.5e-13 47.8 0.2 1.7e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ12813.1 - 3.1e-11 42.8 0.1 5.4e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAJ12813.1 - 4.1e-08 33.4 1.6 7e-08 32.7 0.4 2.0 2 0 0 2 2 2 1 GAT domain HEPN_AbiU2 PF18734.1 OAJ12813.1 - 0.0017 17.9 0.6 0.0029 17.1 0.6 1.4 1 0 0 1 1 1 1 AbiU2 Hrs_helical PF12210.8 OAJ12813.1 - 0.011 16.2 0.2 0.011 16.2 0.2 2.1 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.20 OAJ12813.1 - 5.7 7.1 10.5 0.033 14.1 1.8 2.0 2 0 0 2 2 2 0 Ubiquitin interaction motif HEAT_EZ PF13513.6 OAJ12814.1 - 2.3e-24 85.4 10.7 3.5e-06 27.4 0.0 9.9 9 1 1 10 10 10 5 HEAT-like repeat HEAT PF02985.22 OAJ12814.1 - 9e-21 72.2 8.8 5e-05 23.2 0.2 9.1 8 0 0 8 8 7 6 HEAT repeat HEAT_2 PF13646.6 OAJ12814.1 - 9e-18 64.5 14.9 0.0021 18.4 0.1 8.3 4 3 3 7 7 7 4 HEAT repeats UME PF08064.13 OAJ12814.1 - 4.7e-10 39.3 0.0 0.077 12.9 0.0 5.3 4 2 1 5 5 5 3 UME (NUC010) domain IBN_N PF03810.19 OAJ12814.1 - 3.4e-08 33.3 0.3 3.4e-08 33.3 0.3 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 OAJ12814.1 - 6.2e-08 32.9 0.2 0.0018 18.4 0.0 4.3 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAJ12814.1 - 4e-07 29.5 3.0 0.014 14.5 0.0 5.5 6 1 1 7 7 7 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 OAJ12814.1 - 9.3e-07 27.8 2.0 0.054 12.0 0.0 4.3 4 0 0 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OAJ12814.1 - 7.6e-06 26.4 0.0 0.61 10.7 0.0 5.6 4 2 4 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAJ12814.1 - 4.3e-05 23.2 0.0 8.9 5.8 0.0 5.2 4 2 1 6 6 6 1 CLASP N terminal CAS_CSE1 PF03378.15 OAJ12814.1 - 0.00017 20.3 1.8 0.095 11.2 0.0 4.3 5 0 0 5 5 5 1 CAS/CSE protein, C-terminus Cohesin_HEAT PF12765.7 OAJ12814.1 - 0.00038 20.7 0.2 0.94 9.8 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RTP1_C1 PF10363.9 OAJ12814.1 - 0.0035 17.5 0.4 14 5.9 0.1 4.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 OAJ12814.1 - 0.0064 16.4 2.5 81 3.1 0.0 6.3 7 1 0 8 8 8 0 Domain of unknown function (DUF3385) UNC45-central PF11701.8 OAJ12814.1 - 0.069 13.1 0.5 23 4.9 0.1 3.4 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Arm PF00514.23 OAJ12814.1 - 1.5 9.0 10.8 36 4.6 0.1 6.5 9 0 0 9 9 8 0 Armadillo/beta-catenin-like repeat dsDNA_bind PF01984.20 OAJ12815.1 - 1.3e-30 105.9 10.7 6.7e-30 103.6 10.7 1.9 1 1 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_60s PF00428.19 OAJ12815.1 - 0.6 10.7 5.6 1.6 9.4 0.0 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein Aha1_N PF09229.11 OAJ12816.1 - 1.9e-28 99.4 0.0 3e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAJ12816.1 - 6.9e-17 61.8 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein NUDE_C PF04880.13 OAJ12816.1 - 0.2 12.1 5.1 0.32 11.5 5.1 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region INO80_Ies4 PF08193.11 OAJ12816.1 - 0.33 10.9 9.7 0.51 10.3 9.7 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Rib_recp_KP_reg PF05104.12 OAJ12816.1 - 4.6 8.3 9.5 9.9 7.2 9.5 1.5 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region FSA_C PF10479.9 OAJ12816.1 - 6.3 4.8 9.5 8.9 4.3 9.5 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2237 PF09996.9 OAJ12817.1 - 3.7e-37 126.8 0.0 4.6e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PIG-S PF10510.9 OAJ12819.1 - 2e-108 363.4 0.0 3.4e-108 362.7 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Phage_TAC_4 PF08748.11 OAJ12819.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Myosin_head PF00063.21 OAJ12820.1 - 3.5e-262 871.5 0.3 5.3e-262 871.0 0.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 OAJ12820.1 - 1.8e-27 95.7 1.0 1.8e-27 95.7 1.0 3.1 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 OAJ12820.1 - 6.9e-07 28.5 31.0 0.56 10.1 0.4 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif Fib_alpha PF08702.10 OAJ12820.1 - 0.0048 17.1 5.6 0.0048 17.1 5.6 2.7 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family AAA_22 PF13401.6 OAJ12820.1 - 0.005 17.1 0.0 0.024 14.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain TolA_bind_tri PF16331.5 OAJ12820.1 - 0.011 15.8 2.7 0.011 15.8 2.7 3.3 2 0 0 2 2 2 0 TolA binding protein trimerisation FlxA PF14282.6 OAJ12820.1 - 0.019 14.9 10.7 0.3 11.1 2.8 2.9 2 0 0 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.7 OAJ12820.1 - 0.22 11.6 18.6 0.45 10.7 17.9 1.9 1 1 0 1 1 1 0 Tropomyosin like DivIC PF04977.15 OAJ12820.1 - 0.28 11.0 14.8 0.011 15.5 6.9 2.9 2 1 1 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 OAJ12820.1 - 0.31 11.5 2.3 2.3 8.7 2.3 2.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) AAA_16 PF13191.6 OAJ12820.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.0 2 1 2 4 4 4 0 AAA ATPase domain GAS PF13851.6 OAJ12820.1 - 1.4 8.2 22.1 3.4 7.0 22.1 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 OAJ12820.1 - 2.1 8.9 5.4 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter AAA_13 PF13166.6 OAJ12820.1 - 2.3 6.7 16.7 4.1 5.9 15.9 1.7 1 1 1 2 2 2 0 AAA domain Med9 PF07544.13 OAJ12820.1 - 2.7 8.1 15.1 1.1 9.4 2.5 3.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 OAJ12820.1 - 2.9 8.0 27.4 5.1 7.2 9.1 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 OAJ12820.1 - 5 7.5 10.3 1.2 9.4 2.5 3.2 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OrsD PF12013.8 OAJ12820.1 - 6.8 7.2 5.5 2.8 8.4 0.9 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ammonium_transp PF00909.21 OAJ12821.1 - 5.9e-106 354.5 25.7 6.8e-106 354.3 25.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TMEM252 PF15664.5 OAJ12830.1 - 0.17 11.6 0.2 0.35 10.6 0.1 1.6 1 1 0 1 1 1 0 Transmembrane protein 252 family Histone PF00125.24 OAJ12831.1 - 0.026 14.9 0.1 0.026 14.9 0.1 2.8 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Adeno_terminal PF02459.15 OAJ12831.1 - 0.21 9.9 2.7 0.42 8.9 2.7 1.5 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RVT_1 PF00078.27 OAJ12832.1 - 1.6e-23 83.4 0.0 2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CSN4_RPN5_eIF3a PF18420.1 OAJ12833.1 - 0.00058 20.0 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain DUF5315 PF17242.2 OAJ12833.1 - 0.013 15.3 0.2 0.032 14.1 0.2 1.6 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) BST2 PF16716.5 OAJ12833.1 - 0.034 14.7 0.4 0.068 13.8 0.3 1.6 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Exo_endo_phos_2 PF14529.6 OAJ12833.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1840 PF08895.11 OAJ12834.1 - 0.11 12.8 0.2 0.49 10.7 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Transposase_21 PF02992.14 OAJ12835.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 ARTD15_N PF18084.1 OAJ12837.1 - 0.13 12.6 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 ARTD15 N-terminal domain JmjC PF02373.22 OAJ12838.1 - 0.0025 18.2 0.1 0.0067 16.8 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase UPF0489 PF12640.7 OAJ12838.1 - 0.0049 17.1 0.0 0.0081 16.4 0.0 1.3 1 0 0 1 1 1 1 UPF0489 domain PI3Ka PF00613.20 OAJ12848.1 - 4.5e-52 176.2 0.0 6.5e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 OAJ12848.1 - 3.3e-33 114.6 0.0 5e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.27 OAJ12848.1 - 1.1e-28 100.8 0.0 2.3e-25 89.9 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase C2 PF00168.30 OAJ12848.1 - 0.003 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Tic110 PF16940.5 OAJ12848.1 - 1.9 6.9 4.3 3.1 6.2 4.3 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter Transketolase_N PF00456.21 OAJ12849.1 - 5.4e-15 55.2 2.6 3.9e-13 49.1 2.7 2.3 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 OAJ12849.1 - 3.1e-12 46.5 0.0 1.2e-11 44.6 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 OAJ12849.1 - 7.2e-05 22.5 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 OAJ12849.1 - 0.0075 16.6 0.1 0.029 14.7 0.1 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II TPP_enzyme_C PF02775.21 OAJ12849.1 - 0.13 12.1 0.0 0.45 10.3 0.0 1.9 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ACBP PF00887.19 OAJ12850.1 - 1.9e-23 82.5 0.0 3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Cwf_Cwc_15 PF04889.12 OAJ12850.1 - 0.012 15.4 13.8 0.017 14.9 13.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 OAJ12850.1 - 0.045 13.9 8.6 0.065 13.3 8.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC27 PF09507.10 OAJ12850.1 - 0.059 12.8 4.7 0.084 12.3 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 OAJ12850.1 - 0.084 12.2 17.3 0.12 11.7 17.3 1.1 1 0 0 1 1 1 0 NOA36 protein Retinal PF15449.6 OAJ12850.1 - 0.36 8.6 2.8 0.49 8.1 2.8 1.1 1 0 0 1 1 1 0 Retinal protein RRN3 PF05327.11 OAJ12850.1 - 0.43 9.1 5.4 0.56 8.7 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAJ12850.1 - 1.5 8.7 9.5 2.3 8.1 9.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.18 OAJ12850.1 - 1.8 8.4 4.4 2.7 7.8 4.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2722 PF10846.8 OAJ12850.1 - 1.9 7.3 5.1 3 6.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pes-10 PF07149.11 OAJ12850.1 - 2 7.4 6.2 3 6.8 6.2 1.2 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 OAJ12850.1 - 2.1 7.7 11.2 2.9 7.2 11.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ12850.1 - 2.2 7.6 11.7 3.1 7.0 11.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 OAJ12850.1 - 2.4 7.7 16.2 3.6 7.1 16.2 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.9 OAJ12850.1 - 3.1 6.9 22.1 4.7 6.2 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCIP PF13324.6 OAJ12850.1 - 3.1 7.3 6.8 7.3 6.1 7.0 1.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FAM176 PF14851.6 OAJ12850.1 - 3.5 7.3 7.8 7.3 6.2 7.8 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 OAJ12850.1 - 3.6 7.3 7.5 5.9 6.6 7.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 OAJ12850.1 - 3.8 5.6 12.6 5.1 5.2 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 OAJ12850.1 - 4.8 7.2 9.8 7.3 6.6 9.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 OAJ12850.1 - 7.5 7.0 17.3 2.7 8.4 14.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_1 PF03184.19 OAJ12851.1 - 6e-41 140.0 0.1 9.3e-41 139.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ12851.1 - 2.8e-11 43.3 0.0 6.7e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FAE1_CUT1_RppA PF08392.12 OAJ12851.1 - 0.2 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein SSF PF00474.17 OAJ12852.1 - 4.6e-22 78.4 27.8 7.9e-22 77.7 27.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family CDH-cyt PF16010.5 OAJ12854.1 - 6.5e-10 39.0 3.9 1.2e-09 38.2 3.9 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ12854.1 - 3e-09 37.1 8.5 5.2e-09 36.4 8.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ12854.1 - 0.0002 21.5 0.3 0.00056 20.1 0.2 1.7 2 0 0 2 2 2 1 DOMON domain Wzy_C_2 PF11846.8 OAJ12854.1 - 0.036 14.0 0.2 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF4079 PF13301.6 OAJ12854.1 - 0.47 10.6 11.6 8.1 6.6 10.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 OAJ12854.1 - 0.47 10.3 5.2 2.7 7.8 4.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF1768 PF08719.11 OAJ12865.1 - 5.4e-20 72.3 0.0 7.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Glyco_hydro_92 PF07971.12 OAJ12866.1 - 1e-103 347.7 0.0 1.5e-103 347.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ12866.1 - 6.6e-42 144.0 1.1 1.1e-41 143.3 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ABC_tran PF00005.27 OAJ12867.1 - 7.1e-08 33.1 0.1 1.2e-07 32.3 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 OAJ12867.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAJ12867.1 - 0.0012 18.5 0.2 0.0038 16.9 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ12867.1 - 0.004 17.6 0.1 0.0074 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAJ12867.1 - 0.004 17.1 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain DLIC PF05783.11 OAJ12867.1 - 0.0069 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 OAJ12867.1 - 0.0079 16.7 0.1 0.012 16.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ12867.1 - 0.011 16.3 0.0 0.023 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ12867.1 - 0.016 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ12867.1 - 0.02 15.1 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ12867.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 OAJ12867.1 - 0.045 12.6 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 OAJ12867.1 - 0.048 13.4 0.2 0.089 12.5 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ12867.1 - 0.058 13.1 0.1 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OAJ12867.1 - 0.06 13.1 0.1 0.083 12.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 OAJ12867.1 - 0.084 13.3 0.1 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 OAJ12867.1 - 0.087 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 OAJ12867.1 - 0.099 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ12867.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ12867.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein RecA PF00154.21 OAJ12867.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.4 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Gram_pos_anchor PF00746.21 OAJ12867.1 - 6.7 6.8 6.0 6.4 6.8 4.2 2.0 1 1 0 1 1 1 0 LPXTG cell wall anchor motif DUF1768 PF08719.11 OAJ12868.1 - 4.7e-23 82.2 0.0 1.4e-22 80.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 OAJ12869.1 - 2.4e-21 76.6 0.4 3.4e-21 76.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 OAJ12869.1 - 0.2 11.5 0.3 0.44 10.4 0.2 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 OAJ12870.1 - 2.8e-41 141.1 0.1 4.1e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12870.1 - 4.2e-22 78.9 0.0 6.1e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ12870.1 - 1.6e-05 24.9 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Sod_Fe_C PF02777.18 OAJ12871.1 - 5.7e-18 65.0 0.1 2.1e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ12871.1 - 0.0008 19.8 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FAM199X PF15814.5 OAJ12871.1 - 1.5 7.8 6.1 3.4 6.6 6.1 1.5 1 0 0 1 1 1 0 Protein family FAM199X TMEM70 PF06979.12 OAJ12872.1 - 0.00058 20.3 0.1 0.00091 19.7 0.1 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex BTB PF00651.31 OAJ12873.1 - 8.7e-06 25.9 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1768 PF08719.11 OAJ12874.1 - 1e-24 87.6 0.0 2e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) WW PF00397.26 OAJ12882.1 - 5.7e-08 32.7 7.2 5e-07 29.7 6.8 2.5 2 0 0 2 2 2 1 WW domain Hydrolase_2 PF07486.12 OAJ12882.1 - 0.11 13.3 0.4 0.26 12.2 0.4 1.8 1 0 0 1 1 1 0 Cell Wall Hydrolase QRPTase_N PF02749.16 OAJ12883.1 - 1.9e-18 66.3 0.1 4.8e-17 61.8 0.1 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Dus PF01207.17 OAJ12884.1 - 2e-61 207.8 0.0 1.4e-52 178.7 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TPR_1 PF00515.28 OAJ12884.1 - 5.1e-05 22.9 3.2 0.65 9.9 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ12884.1 - 0.0033 17.1 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 OAJ12884.1 - 0.04 14.0 2.5 1.4 9.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ12884.1 - 0.068 13.6 0.8 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ12884.1 - 0.36 11.1 4.3 25 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fringe PF02434.16 OAJ12885.1 - 1.3e-08 34.6 0.7 4.8e-08 32.8 0.6 1.9 1 1 0 1 1 1 1 Fringe-like PMT PF02366.18 OAJ12886.1 - 3.4e-75 252.8 12.7 5.9e-75 252.0 12.7 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ12886.1 - 5.7e-64 215.4 17.7 5.7e-64 215.4 17.7 2.1 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ12886.1 - 7.7e-37 126.9 0.0 2e-36 125.6 0.0 1.7 1 0 0 1 1 1 1 MIR domain NTP_transferase PF00483.23 OAJ12887.1 - 4.3e-43 147.7 0.0 7.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 OAJ12887.1 - 5.8e-06 26.3 0.1 1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Fes1 PF08609.10 OAJ12888.1 - 8.8e-17 61.8 5.3 9.4e-17 61.7 0.1 3.1 3 1 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 OAJ12888.1 - 2e-05 24.5 4.1 0.33 11.3 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat Adaptin_N PF01602.20 OAJ12888.1 - 0.0064 15.1 0.5 0.33 9.5 0.0 2.1 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ12888.1 - 0.026 15.1 3.1 6.5 7.4 0.1 3.9 4 0 0 4 4 4 0 HEAT-like repeat Thioredoxin PF00085.20 OAJ12889.1 - 7.8e-26 90.1 0.0 9.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ12889.1 - 3.4e-07 30.7 0.1 4e-06 27.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ12889.1 - 7.2e-06 26.3 0.0 1.9e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ12889.1 - 9.7e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 OAJ12889.1 - 1.3e-05 25.0 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 OAJ12889.1 - 9.4e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 OAJ12889.1 - 0.00029 20.3 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 OAJ12889.1 - 0.0003 20.5 0.1 0.00072 19.3 0.1 1.5 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 OAJ12889.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.11 OAJ12889.1 - 0.037 14.0 0.0 0.058 13.4 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-RING_2 PF13639.6 OAJ12890.1 - 2.8e-09 37.1 9.5 3.6e-07 30.4 1.0 3.7 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ12890.1 - 8.8e-06 25.6 0.4 0.013 15.6 0.3 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-rbx1 PF12678.7 OAJ12890.1 - 6.1e-05 23.2 9.2 0.00087 19.5 2.5 3.1 3 0 0 3 3 3 2 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ12890.1 - 0.00012 21.8 4.5 0.055 13.3 0.5 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ12890.1 - 0.00017 21.5 3.0 0.083 12.9 0.4 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ12890.1 - 0.0084 16.1 5.7 0.017 15.2 0.7 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ12890.1 - 0.032 14.0 6.4 6.6 6.6 0.3 3.5 3 0 0 3 3 3 0 RING-like zinc finger RINGv PF12906.7 OAJ12890.1 - 0.11 12.7 3.0 0.39 10.9 3.0 2.1 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 OAJ12890.1 - 0.18 11.7 11.0 1.1 9.2 0.1 3.3 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ12890.1 - 0.25 11.0 6.7 0.23 11.1 1.5 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAJ12890.1 - 0.34 10.8 10.4 0.43 10.5 1.8 3.6 3 1 0 3 3 3 0 PHD-finger TFIIA PF03153.13 OAJ12890.1 - 1.6 8.6 21.8 0.035 14.1 8.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-4CXXC_R1 PF10497.9 OAJ12890.1 - 1.7 8.9 4.2 9.2 6.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 OAJ12890.1 - 1.8 8.5 10.7 0.42 10.5 0.3 3.4 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 Serglycin PF04360.12 OAJ12891.1 - 0.0027 17.7 1.2 0.0053 16.7 1.2 1.4 1 0 0 1 1 1 1 Serglycin CAF1A PF12253.8 OAJ12891.1 - 0.019 15.1 4.4 0.037 14.2 1.5 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Cytochrom_B_C PF00032.17 OAJ12892.1 - 0.03 14.6 1.3 0.03 14.6 1.3 2.5 1 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD YfzA PF14118.6 OAJ12892.1 - 0.037 14.4 1.8 11 6.5 0.1 2.8 2 0 0 2 2 2 0 YfzA-like protein Pilin_N PF07790.11 OAJ12892.1 - 0.84 10.6 3.8 0.52 11.3 0.7 2.2 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Peptidase_M17 PF00883.21 OAJ12903.1 - 4.3e-10 39.4 0.2 5e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M28 PF04389.17 OAJ12904.1 - 0.027 14.1 0.0 0.062 13.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Ribonuclease_3 PF00636.26 OAJ12905.1 - 1.4e-37 128.5 0.0 4.5e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ12905.1 - 2.2e-23 82.8 3.9 1.3e-13 51.2 0.3 3.6 3 1 0 3 3 3 2 Ribonuclease-III-like Cep57_MT_bd PF06657.13 OAJ12906.1 - 0.0056 17.1 7.9 0.068 13.6 0.4 3.7 3 0 0 3 3 3 2 Centrosome microtubule-binding domain of Cep57 Transposase_21 PF02992.14 OAJ12909.1 - 9.4e-17 61.0 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Astro_capsid_p PF12226.8 OAJ12909.1 - 1.3 8.1 10.3 2.2 7.4 10.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RXT2_N PF08595.11 OAJ12909.1 - 3.5 7.6 7.5 8.3 6.4 7.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Histone PF00125.24 OAJ12910.1 - 3.2e-20 72.8 0.1 4e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 NPV_P10 PF05531.12 OAJ12912.1 - 0.072 13.6 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 OAJ12912.1 - 0.2 12.2 11.2 0.79 10.2 4.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region JHY PF15261.6 OAJ12913.1 - 0.012 16.3 0.1 0.012 16.3 0.1 2.5 2 1 0 2 2 2 0 Jhy protein PRKG1_interact PF15898.5 OAJ12913.1 - 0.44 11.5 16.0 0.071 14.0 5.0 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Prominin PF05478.11 OAJ12913.1 - 0.8 7.6 4.9 0.24 9.3 2.0 1.4 1 1 0 1 1 1 0 Prominin AAA_13 PF13166.6 OAJ12913.1 - 1.2 7.6 12.0 1.7 7.2 12.0 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 OAJ12913.1 - 3.6 7.6 9.6 0.7 9.9 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAJ12913.1 - 3.8 6.7 11.0 0.12 11.6 3.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein Sfi1 PF08457.10 OAJ12925.1 - 2.6e-23 82.4 89.0 1e-13 50.7 22.7 5.8 1 1 4 5 5 5 5 Sfi1 spindle body protein Ribosomal_60s PF00428.19 OAJ12925.1 - 0.56 10.8 6.1 0.14 12.7 0.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein HAP1_N PF04849.13 OAJ12926.1 - 0.44 9.7 25.0 1.1 8.4 23.8 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region HALZ PF02183.18 OAJ12926.1 - 0.98 9.7 6.8 5.6 7.3 0.2 4.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 OAJ12926.1 - 1.4 8.9 19.6 1.3 9.0 5.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFIIS_M PF07500.14 OAJ12927.1 - 1.1e-23 83.9 0.1 1.7e-23 83.2 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAJ12927.1 - 8.1e-10 38.4 6.6 1.3e-09 37.8 6.6 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 OAJ12927.1 - 1e-05 25.5 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD_4 PF16866.5 OAJ12927.1 - 0.39 10.9 4.2 0.77 9.9 4.2 1.4 1 0 0 1 1 1 0 PHD-finger PFK PF00365.20 OAJ12928.1 - 3.3e-182 604.1 0.0 3.2e-101 338.4 0.0 2.5 2 1 0 2 2 2 2 Phosphofructokinase Exo_endo_phos PF03372.23 OAJ12928.1 - 1.7e-11 44.1 0.0 1.6e-10 40.9 0.0 2.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transposase_mut PF00872.18 OAJ12928.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Zip PF02535.22 OAJ12929.1 - 5e-27 95.0 27.0 2e-20 73.3 1.5 4.1 3 1 1 4 4 4 3 ZIP Zinc transporter ATE_C PF04377.15 OAJ12929.1 - 0.044 14.4 0.0 0.24 12.0 0.0 2.0 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus Mg-por_mtran_C PF07109.11 OAJ12929.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus DUF4611 PF15387.6 OAJ12929.1 - 0.14 12.4 2.0 0.57 10.4 2.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HORMA PF02301.18 OAJ12941.1 - 5.8e-07 29.3 0.0 1.4e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 HORMA domain Vps54 PF07928.12 OAJ12942.1 - 1.6e-52 177.5 1.5 1.6e-52 177.5 1.5 2.7 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 OAJ12942.1 - 0.00011 21.6 1.5 0.00011 21.6 1.5 2.3 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex SCHIP-1 PF10148.9 OAJ12943.1 - 5.6 6.5 6.2 5 6.7 1.2 2.2 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 Pkinase PF00069.25 OAJ12944.1 - 2.7e-56 190.8 0.0 3.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12944.1 - 9e-29 100.5 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ12944.1 - 1.8e-05 24.2 0.0 4.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ12944.1 - 0.05 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ12944.1 - 0.09 12.7 0.1 7.1 6.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 OAJ12944.1 - 0.14 11.8 0.0 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 OAJ12944.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Hamartin PF04388.12 OAJ12944.1 - 1.8 7.1 10.9 2.1 6.9 10.9 1.1 1 0 0 1 1 1 0 Hamartin protein SNF2_N PF00176.23 OAJ12945.1 - 2.7e-56 190.8 0.1 4.1e-56 190.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ12945.1 - 1.5e-16 60.7 0.0 5.5e-16 58.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ12945.1 - 1.4e-08 34.9 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ12945.1 - 4.5e-07 29.3 1.9 4.7e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 OAJ12945.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RRF_GI PF12614.8 OAJ12945.1 - 0.17 12.1 2.7 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Ribosome recycling factor TrwB_AAD_bind PF10412.9 OAJ12945.1 - 0.64 8.9 4.9 0.21 10.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FAR1 PF03101.15 OAJ12946.1 - 0.0041 17.8 0.1 0.0058 17.3 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Wtap PF17098.5 OAJ12947.1 - 0.0077 16.2 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family GLTSCR1 PF15249.6 OAJ12947.1 - 0.12 12.8 0.5 0.23 11.9 0.5 1.4 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein MULE PF10551.9 OAJ12948.1 - 7.4e-09 35.9 0.3 7.1e-08 32.8 0.0 2.5 2 1 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ12948.1 - 4.4e-05 22.5 0.2 6.4e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF4663 PF15668.5 OAJ12949.1 - 3.2 6.7 7.5 5.4 6.0 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Pkinase PF00069.25 OAJ12956.1 - 2.7e-72 243.3 0.0 3.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12956.1 - 5.2e-41 140.6 0.0 7.5e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ12956.1 - 2.5e-08 33.1 0.1 4.7e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ12956.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ12956.1 - 1.3e-06 28.0 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ12956.1 - 0.00064 19.3 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 OAJ12956.1 - 0.0025 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 OAJ12956.1 - 0.26 11.4 0.9 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain Spt20 PF12090.8 OAJ12957.1 - 0.0014 18.3 12.7 0.0014 18.3 12.7 1.1 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 OAJ12957.1 - 0.18 11.8 12.6 0.17 11.8 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 OAJ12957.1 - 0.25 12.3 5.9 0.28 12.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 OAJ12957.1 - 0.5 9.2 13.0 0.46 9.3 13.0 1.1 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 OAJ12957.1 - 0.77 8.5 2.5 0.68 8.6 2.5 1.0 1 0 0 1 1 1 0 Presenilin Med3 PF11593.8 OAJ12957.1 - 3.9 6.6 15.3 4.2 6.5 15.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2722 PF10846.8 OAJ12957.1 - 7.6 5.3 17.8 9.3 5.1 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) V-SNARE_C PF12352.8 OAJ12958.1 - 5.7e-17 61.8 4.0 1.1e-16 60.8 4.0 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ12958.1 - 0.00032 20.6 0.1 0.00081 19.3 0.1 1.7 1 0 0 1 1 1 1 Sec20 BCDHK_Adom3 PF10436.9 OAJ12959.1 - 7.4e-39 133.2 0.0 1.1e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ12959.1 - 1.1e-09 38.8 0.0 1.2e-05 25.8 0.0 3.3 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ12959.1 - 7.1e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FdhE PF04216.12 OAJ12959.1 - 0.07 13.0 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation ABC_membrane PF00664.23 OAJ12960.1 - 2.3e-79 266.9 18.4 7.2e-43 147.2 3.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ12960.1 - 6.1e-49 166.1 0.0 8.2e-30 104.1 0.1 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ12960.1 - 2.3e-06 27.2 0.2 0.026 13.9 0.0 3.7 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ12960.1 - 3.9e-05 24.1 0.7 0.032 14.6 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ12960.1 - 0.00011 22.3 0.3 0.19 11.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ12960.1 - 0.0017 18.3 0.1 0.78 9.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OAJ12960.1 - 0.0042 17.2 0.3 0.6 10.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 OAJ12960.1 - 0.0047 17.0 3.6 0.25 11.4 0.1 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_29 PF13555.6 OAJ12960.1 - 0.012 15.4 0.7 7.8 6.3 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAJ12960.1 - 0.026 14.3 0.3 13 5.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAJ12960.1 - 0.061 13.0 0.6 13 5.4 0.2 2.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAJ12960.1 - 0.084 11.9 0.0 1.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zip PF02535.22 OAJ12961.1 - 6.3e-60 203.2 10.1 7.1e-60 203.0 10.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Usp PF00582.26 OAJ12962.1 - 4.1 7.9 4.9 35 4.9 0.1 3.4 3 1 1 4 4 4 0 Universal stress protein family zf-C2H2 PF00096.26 OAJ12963.1 - 3.1e-05 24.2 6.4 0.005 17.2 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ12963.1 - 0.00056 20.5 7.6 0.013 16.3 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ12963.1 - 0.02 14.9 5.2 1.6 8.8 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 OAJ12963.1 - 0.21 11.2 0.3 0.47 10.1 0.3 1.7 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 OAJ12963.1 - 0.38 11.3 4.7 2.6 8.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain YchF-GTPase_C PF06071.13 OAJ12964.1 - 1.6e-34 118.0 0.3 5.9e-34 116.1 0.1 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAJ12964.1 - 2.1e-17 63.2 0.0 4.4e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ12964.1 - 8.3e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B IFT81_CH PF18383.1 OAJ12964.1 - 0.13 12.5 0.7 0.24 11.7 0.7 1.3 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain Peptidase_S8 PF00082.22 OAJ12965.1 - 8.4e-38 130.3 2.8 1.4e-37 129.6 2.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OAJ12965.1 - 1.1e-25 89.5 0.2 2.2e-25 88.5 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAJ12965.1 - 0.0064 17.2 0.0 0.0064 17.2 0.0 2.5 1 1 1 2 2 2 1 Peptidase S8 pro-domain DUF1180 PF06679.12 OAJ12965.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1180) MHYT PF03707.16 OAJ12965.1 - 1.2 9.4 6.4 4.6 7.5 0.1 3.2 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat COX6B PF02297.17 OAJ12978.1 - 1.3e-13 51.0 11.9 5.2e-13 49.0 6.7 2.2 2 0 0 2 2 2 2 Cytochrome oxidase c subunit VIb zf-CHY PF05495.12 OAJ12979.1 - 2.7e-13 50.2 10.8 5.8e-13 49.1 10.8 1.5 1 1 0 1 1 1 1 CHY zinc finger TF_Zn_Ribbon PF08271.12 OAJ12979.1 - 0.058 12.9 2.8 0.17 11.4 1.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Cys_rich_KTR PF14205.6 OAJ12979.1 - 0.15 11.9 5.2 0.093 12.5 1.8 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR Elf1 PF05129.13 OAJ12979.1 - 0.53 10.4 7.8 0.072 13.1 3.8 1.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 OAJ12979.1 - 0.9 9.6 8.7 17 5.5 8.7 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 OAJ12979.1 - 4.9 7.2 11.5 33 4.5 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ACBP PF00887.19 OAJ12980.1 - 1.5e-29 102.0 0.2 1.9e-29 101.7 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein LPD3 PF18798.1 OAJ12980.1 - 0.079 13.2 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 3 KH_1 PF00013.29 OAJ12981.1 - 7e-47 157.1 9.5 7e-18 64.2 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ12981.1 - 2.1e-15 56.3 5.9 2.9e-05 23.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ12981.1 - 5.9e-06 26.1 1.5 0.94 9.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ12981.1 - 0.0088 16.1 7.9 0.39 10.8 0.2 3.6 3 1 0 3 3 3 2 NusA-like KH domain Sugar_tr PF00083.24 OAJ12982.1 - 3e-86 290.1 13.1 2e-71 241.2 3.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ12982.1 - 1.4e-22 80.2 14.5 1.4e-22 80.2 14.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3809 PF12723.7 OAJ12982.1 - 0.13 12.5 0.1 0.24 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) DUF2929 PF11151.8 OAJ12982.1 - 2.5 8.5 6.8 16 5.9 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Sugar_tr PF00083.24 OAJ12983.1 - 1.2e-102 344.2 17.1 1.5e-102 343.8 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ12983.1 - 1.1e-16 60.7 25.4 1.1e-16 60.7 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_pol_E_B PF04042.16 OAJ12985.1 - 2.8e-37 128.1 0.0 5.7e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAJ12985.1 - 6.6e-37 126.5 0.0 1.1e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF4746 PF15928.5 OAJ12985.1 - 0.4 10.1 2.1 1.5 8.2 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RXT2_N PF08595.11 OAJ12985.1 - 2.4 8.2 5.8 4 7.4 1.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal COX16 PF14138.6 OAJ12986.1 - 1.7e-27 95.8 0.1 4.3e-27 94.4 0.1 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.13 OAJ12986.1 - 4e-24 85.0 0.0 1.1e-23 83.6 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family ADH_N PF08240.12 OAJ12998.1 - 2.9e-26 91.5 2.2 7.2e-26 90.2 2.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ12998.1 - 1.2e-22 80.3 0.1 2e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAJ12998.1 - 0.0079 15.5 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PQQ PF01011.21 OAJ12998.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat DUF4451 PF14616.6 OAJ12999.1 - 3.7e-23 82.0 0.3 8.6e-23 80.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Zn_clus PF00172.18 OAJ13000.1 - 1.5e-06 28.2 10.6 1.5e-06 28.2 10.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DGF-1_C PF11040.8 OAJ13000.1 - 6.2 6.9 7.3 49 4.0 0.1 3.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Pkinase PF00069.25 OAJ13001.1 - 1.9e-62 211.0 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13001.1 - 2.4e-38 131.9 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ13001.1 - 2.5e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.13 OAJ13001.1 - 0.0065 16.5 8.3 0.0084 16.2 8.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 OAJ13001.1 - 0.13 11.0 0.0 0.35 9.6 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase DUF4790 PF16037.5 OAJ13001.1 - 0.22 12.0 4.8 8.8 6.9 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4790) Chitin_synth_1 PF01644.17 OAJ13002.1 - 6.4e-79 263.6 0.0 1.3e-78 262.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ13002.1 - 8.5e-27 92.9 0.0 1.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ13002.1 - 1.4e-23 83.3 3.5 7.8e-17 61.1 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ13002.1 - 5e-05 23.3 6.8 0.0002 21.4 6.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 LRR19-TM PF15176.6 OAJ13002.1 - 0.02 14.9 0.7 0.063 13.3 0.7 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2781 PF10914.8 OAJ13005.1 - 5e-34 117.8 7.2 5.7e-34 117.6 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) WD40 PF00400.32 OAJ13014.1 - 0.4 11.6 1.6 2.2e+02 3.0 0.0 4.9 6 0 0 6 6 6 0 WD domain, G-beta repeat SSB PF00436.25 OAJ13015.1 - 7.7e-15 54.8 0.0 9.2e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Pkinase PF00069.25 OAJ13017.1 - 2.7e-70 236.8 0.0 3.5e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13017.1 - 7.8e-39 133.5 0.0 1.2e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ13017.1 - 1.5e-05 24.5 0.1 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ13017.1 - 0.0003 20.4 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OAJ13017.1 - 0.00055 19.3 0.1 0.0084 15.5 0.0 2.6 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OAJ13017.1 - 0.0049 15.7 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAJ13017.1 - 0.01 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 OAJ13017.1 - 0.022 14.7 0.3 0.082 12.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family SMI1_KNR4 PF09346.10 OAJ13018.1 - 8.6e-22 78.0 0.0 1.6e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) TPR_1 PF00515.28 OAJ13019.1 - 4.8e-11 42.0 0.7 0.0049 16.6 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13019.1 - 5.1e-11 41.8 2.6 0.014 15.4 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ13019.1 - 1.1e-06 29.2 5.3 4.8e-05 23.9 0.9 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ13019.1 - 9.1e-05 22.1 0.4 0.95 9.2 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 OAJ13019.1 - 0.00065 19.8 0.8 0.0028 17.7 0.8 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANTAR PF03861.14 OAJ13019.1 - 0.0057 16.5 0.1 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 ANTAR domain TPR_8 PF13181.6 OAJ13019.1 - 0.035 14.3 0.0 3.5 8.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 OAJ13019.1 - 0.094 12.5 0.7 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Med19 PF10278.9 OAJ13019.1 - 0.25 11.2 12.8 0.14 12.1 0.8 2.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 TPR_14 PF13428.6 OAJ13019.1 - 3.7 8.6 7.7 1.9 9.6 0.4 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat FH2 PF02181.23 OAJ13020.1 - 4.3e-64 217.0 3.7 4.3e-64 217.0 3.7 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAJ13020.1 - 7.2e-44 149.6 0.0 7.2e-44 149.6 0.0 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAJ13020.1 - 1.7e-42 145.3 0.5 1.8e-41 141.9 0.1 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain G-gamma PF00631.22 OAJ13020.1 - 2.6 8.1 4.5 2 8.5 0.2 2.6 2 0 0 2 2 2 0 GGL domain Gly_transf_sug PF04488.15 OAJ13033.1 - 2.9e-07 31.0 0.0 7.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Helicase_C PF00271.31 OAJ13034.1 - 7.4e-17 61.7 0.0 2.1e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 OAJ13034.1 - 2e-15 56.7 0.0 4.6e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 OAJ13034.1 - 3.1e-09 36.9 0.0 7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ13034.1 - 5e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.26 OAJ13034.1 - 0.042 14.6 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif Asp PF00026.23 OAJ13035.1 - 1.5e-59 202.0 9.4 4.7e-59 200.4 9.4 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ13035.1 - 2.2e-09 37.8 3.8 4.9e-05 23.7 0.3 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ13035.1 - 9.4e-05 22.2 0.0 0.0012 18.6 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ13035.1 - 0.0025 18.4 4.2 0.016 15.9 0.4 2.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ13035.1 - 0.033 14.7 0.9 0.084 13.4 0.1 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease KH_1 PF00013.29 OAJ13036.1 - 1.2e-09 37.8 0.0 3.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 OAJ13036.1 - 0.04 14.1 0.1 0.097 12.8 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein RRF PF01765.19 OAJ13036.1 - 0.79 9.7 2.7 2 8.4 0.3 2.4 3 0 0 3 3 3 0 Ribosome recycling factor GRP PF07172.11 OAJ13036.1 - 2.2 9.0 18.0 1.2 9.8 13.8 2.3 2 0 0 2 2 2 0 Glycine rich protein family CPBP PF02517.16 OAJ13037.1 - 6.1e-17 61.8 4.9 2e-16 60.1 4.5 2.2 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease F-box-like PF12937.7 OAJ13037.1 - 0.00075 19.3 0.0 0.0041 17.0 0.0 2.2 1 1 0 1 1 1 1 F-box-like START PF01852.19 OAJ13038.1 - 0.0027 17.2 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 START domain TMA7 PF09072.10 OAJ13038.1 - 4 8.4 10.1 0.35 11.7 4.0 2.4 2 0 0 2 2 2 0 Translation machinery associated TMA7 p450 PF00067.22 OAJ13039.1 - 1.8e-43 149.0 0.0 1.3e-23 83.5 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 PCI PF01399.27 OAJ13040.1 - 0.00046 20.7 0.0 0.0012 19.3 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAJ13040.1 - 0.039 14.1 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.16 OAJ13040.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain PALP PF00291.25 OAJ13041.1 - 5.8e-47 160.5 0.1 9.1e-41 140.2 0.1 3.7 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 OAJ13041.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Inositol_P PF00459.25 OAJ13042.1 - 3.6e-60 203.8 0.0 4.3e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Tubulin_3 PF14881.6 OAJ13050.1 - 3.1e-28 98.7 14.6 4.3e-19 68.9 1.1 4.2 2 1 2 4 4 4 4 Tubulin domain Misat_Tub_SegII PF10644.9 OAJ13050.1 - 3.1e-27 95.2 0.0 1e-26 93.6 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Prok-JAB PF14464.6 OAJ13052.1 - 0.54 10.0 4.4 0.99 9.2 0.9 2.4 1 1 1 2 2 2 0 Prokaryotic homologs of the JAB domain Caskin-Pro-rich PF16907.5 OAJ13055.1 - 0.044 14.3 2.0 0.18 12.3 2.0 2.1 1 0 0 1 1 1 0 Proline rich region of Caskin proteins ING PF12998.7 OAJ13056.1 - 9e-11 42.3 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ13056.1 - 4.3e-05 23.3 8.4 7.5e-05 22.5 8.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-C4pol PF14260.6 OAJ13056.1 - 0.061 13.8 3.7 0.11 13.0 0.7 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta LRR_4 PF12799.7 OAJ13057.1 - 1.9e-23 82.1 26.8 9.9e-06 25.8 0.2 8.1 6 2 2 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ13057.1 - 5.9e-21 74.0 21.1 1.6e-08 34.2 2.7 5.4 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 OAJ13057.1 - 4.2e-07 29.6 8.6 0.02 14.4 0.2 4.1 3 1 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 OAJ13057.1 - 0.0015 18.8 25.3 14 6.7 0.3 9.4 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 OAJ13057.1 - 0.012 15.6 24.8 0.23 11.6 0.1 8.5 8 1 1 9 9 9 0 Leucine Rich repeat DnaJ PF00226.31 OAJ13058.1 - 9.3e-13 48.1 0.0 3.9e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 DnaJ domain zf-CSL PF05207.13 OAJ13058.1 - 1.1e-08 34.7 1.4 3.4e-08 33.1 0.2 2.4 2 1 0 2 2 2 1 CSL zinc finger NOA36 PF06524.12 OAJ13058.1 - 1.4 8.2 8.2 2.3 7.5 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein UPF0547 PF10571.9 OAJ13058.1 - 2.8 8.1 6.2 6.9 6.9 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RasGEF PF00617.19 OAJ13068.1 - 2.6e-40 138.5 0.0 6.5e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ13068.1 - 3.5e-17 62.6 0.0 9e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 OAJ13068.1 - 4.1e-14 52.0 0.1 8.7e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ13068.1 - 1.2e-13 50.6 0.1 3.1e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAJ13068.1 - 7.3e-13 47.9 0.0 1.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain RhoGAP PF00620.27 OAJ13068.1 - 0.13 12.1 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 RhoGAP domain Troponin-I_N PF11636.8 OAJ13068.1 - 7.1 6.7 9.7 0.7 9.9 2.6 3.1 3 0 0 3 3 3 0 Troponin I residues 1-32 PI3_PI4_kinase PF00454.27 OAJ13070.1 - 1.4e-09 38.1 0.0 1.8e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Complex1_LYR PF05347.15 OAJ13071.1 - 1.6e-06 28.1 0.5 2.9e-06 27.2 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ13071.1 - 0.0031 18.2 2.5 0.0041 17.8 2.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like TIMELESS PF04821.14 OAJ13072.1 - 1.1e-70 238.1 0.0 1.1e-70 238.1 0.0 2.3 2 0 0 2 2 2 1 Timeless protein PhoU PF01895.19 OAJ13072.1 - 0.11 12.9 1.6 1.3 9.5 0.0 3.6 4 0 0 4 4 4 0 PhoU domain Pkinase PF00069.25 OAJ13074.1 - 1.2e-21 77.3 0.0 2.4e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13074.1 - 5.2e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ13074.1 - 0.003 16.9 0.0 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ13074.1 - 0.0046 16.3 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ13074.1 - 0.0099 15.8 0.1 0.05 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF202 PF02656.15 OAJ13075.1 - 1.4e-18 67.1 0.1 1.4e-18 67.1 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) KH_1 PF00013.29 OAJ13076.1 - 2.4e-42 142.6 10.0 1.7e-16 59.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ13076.1 - 1.8e-09 37.3 9.5 0.0038 17.0 0.2 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ13076.1 - 5.9e-08 32.5 1.6 0.038 13.9 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ13076.1 - 0.0064 16.5 6.6 0.37 10.9 0.3 3.3 3 0 0 3 3 3 1 NusA-like KH domain dUTPase PF00692.19 OAJ13076.1 - 0.13 12.0 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 dUTPase Not3 PF04065.15 OAJ13087.1 - 3.5e-91 304.7 19.4 3.5e-91 304.7 19.4 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAJ13087.1 - 1.2e-46 158.1 11.5 3.5e-46 156.5 11.5 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAJ13087.1 - 0.0032 17.3 3.0 0.0076 16.1 3.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 OAJ13087.1 - 0.005 17.2 4.1 0.005 17.2 4.1 3.0 3 0 0 3 3 3 1 Syntaxin-like protein Exonuc_VII_S PF02609.16 OAJ13087.1 - 2 8.5 7.8 2.8 8.1 0.5 3.6 3 0 0 3 3 3 0 Exonuclease VII small subunit Ribosomal_L19 PF01245.20 OAJ13088.1 - 3e-15 56.1 0.1 5.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L19 Thioredoxin_10 PF17991.1 OAJ13091.1 - 0.041 14.4 0.1 7.8 7.0 0.0 3.0 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain ATP-synt_8 PF00895.20 OAJ13091.1 - 0.16 12.4 0.2 0.3 11.6 0.2 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 REF PF05755.12 OAJ13092.1 - 5.2 6.8 7.6 2.2 8.0 5.5 1.5 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Goodbye PF17109.5 OAJ13092.1 - 6.5 7.2 9.2 11 6.4 7.0 2.3 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain ABC2_membrane PF01061.24 OAJ13093.1 - 1.2e-32 113.1 17.4 1.9e-32 112.4 17.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ13093.1 - 1.8e-25 90.0 0.0 3e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ13093.1 - 1.2e-06 28.6 2.1 0.0047 16.8 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ13093.1 - 1.5e-05 25.4 0.2 3.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ13093.1 - 0.00036 20.8 0.3 0.0044 17.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAJ13093.1 - 0.00065 19.6 0.1 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 OAJ13093.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 OAJ13093.1 - 0.002 17.8 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ13093.1 - 0.0023 17.6 0.5 0.0086 15.8 0.3 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ13093.1 - 0.0035 17.9 0.0 0.0066 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DLIC PF05783.11 OAJ13093.1 - 0.0073 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) AAA PF00004.29 OAJ13093.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAJ13093.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ13093.1 - 0.024 15.1 0.5 0.047 14.2 0.5 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OAJ13093.1 - 0.039 14.2 0.0 0.3 11.3 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 OAJ13093.1 - 0.045 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ13093.1 - 0.046 13.5 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 OAJ13093.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 OAJ13093.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 OAJ13093.1 - 0.16 12.4 0.0 3.3 8.1 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.19 OAJ13093.1 - 0.17 11.3 0.0 0.68 9.3 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 OAJ13093.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ13093.1 - 0.2 11.4 1.1 0.41 10.3 1.1 1.6 1 1 0 1 1 1 0 AAA domain Cullin PF00888.22 OAJ13103.1 - 5.4e-194 646.3 0.0 7.1e-194 645.9 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ13103.1 - 1.9e-28 98.2 0.4 4.4e-28 97.1 0.4 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 OAJ13103.1 - 0.017 15.4 0.0 0.097 13.0 0.0 2.4 1 0 0 1 1 1 0 Penicillinase repressor TetR_C_29 PF17938.1 OAJ13103.1 - 0.11 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MIEAP PF16026.5 OAJ13103.1 - 1.5 9.0 3.6 3.8 7.7 0.1 2.7 3 0 0 3 3 3 0 Mitochondria-eating protein RhoGEF PF00621.20 OAJ13104.1 - 2.4e-17 63.7 0.0 4.8e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Spt20 PF12090.8 OAJ13104.1 - 0.25 10.9 13.4 0.42 10.2 13.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ13104.1 - 0.27 11.2 11.0 0.53 10.2 11.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Roughex PF06020.11 OAJ13104.1 - 0.44 9.6 2.2 0.67 9.0 2.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ndc1_Nup PF09531.10 OAJ13104.1 - 3.1 6.4 4.6 5.6 5.5 4.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HEAT PF02985.22 OAJ13105.1 - 3.6e-05 23.6 19.4 0.28 11.6 0.1 8.7 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 OAJ13105.1 - 0.00031 21.1 15.2 2.1 8.8 0.0 6.9 6 1 0 6 6 6 3 HEAT repeats Cnd1 PF12717.7 OAJ13105.1 - 0.0016 18.5 1.2 4.6 7.3 0.0 5.0 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OAJ13105.1 - 0.0019 18.2 1.9 0.019 15.0 0.2 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 OAJ13105.1 - 0.1 12.3 0.3 24 4.6 0.0 4.0 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cnd3 PF12719.7 OAJ13105.1 - 0.78 8.9 4.8 23 4.1 0.2 4.1 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain Kelch_4 PF13418.6 OAJ13106.1 - 3e-14 52.7 7.1 2.5e-06 27.4 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ13106.1 - 2.7e-11 43.4 7.0 0.028 14.7 0.4 5.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ13106.1 - 1.3e-10 41.2 4.9 0.02 15.2 0.2 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OAJ13106.1 - 9.1e-09 35.1 1.4 0.016 15.2 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 OAJ13106.1 - 3.1e-08 33.1 0.0 0.0038 16.8 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OAJ13106.1 - 0.024 14.6 0.6 2.1 8.5 0.1 4.0 3 1 0 3 3 3 0 Kelch motif DUF4690 PF15756.5 OAJ13106.1 - 0.071 13.7 2.2 1.6 9.4 0.6 3.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage TMEM51 PF15345.6 OAJ13107.1 - 0.00024 21.0 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 SIT PF15330.6 OAJ13107.1 - 0.0013 19.2 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT Shisa PF13908.6 OAJ13107.1 - 0.0049 17.1 0.0 0.0092 16.2 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 OAJ13107.1 - 0.01 16.7 0.0 0.019 15.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 OAJ13107.1 - 0.015 15.5 1.5 0.023 14.9 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) Tmemb_9 PF05434.11 OAJ13107.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 TMEM9 LRR19-TM PF15176.6 OAJ13107.1 - 0.024 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain LapA_dom PF06305.11 OAJ13107.1 - 0.03 14.2 0.8 0.051 13.4 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4834 PF16118.5 OAJ13107.1 - 0.064 14.2 0.2 0.12 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Amnionless PF14828.6 OAJ13107.1 - 0.14 11.0 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Amnionless Rax2 PF12768.7 OAJ13107.1 - 0.18 11.3 0.3 0.25 10.8 0.3 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SCIMP PF15050.6 OAJ13107.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.6 2 0 0 2 2 2 0 SCIMP protein DUF3094 PF11293.8 OAJ13107.1 - 0.23 11.2 1.4 0.45 10.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Mid2 PF04478.12 OAJ13107.1 - 0.31 10.9 2.5 0.5 10.2 2.2 1.4 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 OAJ13107.1 - 0.75 9.7 2.0 1.1 9.2 0.8 1.9 1 1 0 2 2 2 0 TMEM154 protein family CDP-OH_P_transf PF01066.21 OAJ13108.1 - 7.9e-16 58.6 0.1 7.9e-16 58.6 0.1 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase YjbE PF11106.8 OAJ13108.1 - 0.6 10.4 4.0 1.5 9.1 4.0 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Pkinase PF00069.25 OAJ13109.1 - 2.4e-46 158.3 0.0 3.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13109.1 - 2.4e-44 151.6 0.0 3.3e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OAJ13109.1 - 0.0013 18.6 6.0 0.0025 17.7 6.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 OAJ13109.1 - 0.0041 17.1 0.1 0.0084 16.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ13109.1 - 0.0045 15.8 2.3 0.009 14.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAJ13109.1 - 0.0069 15.8 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ13109.1 - 0.0097 14.9 0.0 0.0097 14.9 0.0 1.8 2 0 0 2 2 1 1 Haspin like kinase domain zf-HC5HC2H_2 PF13832.6 OAJ13109.1 - 0.11 12.7 4.0 0.21 11.7 4.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAJ13109.1 - 0.2 11.9 3.6 0.44 10.8 3.6 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 OAJ13109.1 - 1.6 8.7 6.9 3.1 7.7 6.9 1.4 1 0 0 1 1 1 0 PHD-finger Apt1 PF10351.9 OAJ13109.1 - 1.7 7.4 7.9 3.1 6.6 7.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_M22 PF00814.25 OAJ13119.1 - 4.4e-76 256.1 0.3 8.9e-53 179.7 0.1 2.0 2 0 0 2 2 2 2 Glycoprotease family DUF4035 PF13227.6 OAJ13120.1 - 0.036 13.8 0.4 5.2 6.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) SAM_PNT PF02198.16 OAJ13120.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain F-box PF00646.33 OAJ13121.1 - 3.3e-05 23.6 0.4 6e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ13121.1 - 0.00047 20.0 1.2 0.00091 19.1 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ13122.1 - 3.6e-06 26.7 0.8 3.6e-06 26.7 0.8 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ13122.1 - 0.089 12.7 1.4 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAJ13124.1 - 0.0007 19.4 0.3 0.0015 18.4 0.1 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ13124.1 - 0.079 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAJ13126.1 - 6.7e-08 32.2 0.1 1.1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ13126.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Memo PF01875.17 OAJ13127.1 - 3.1e-69 233.1 0.0 7.8e-69 231.8 0.0 1.6 1 1 0 1 1 1 1 Memo-like protein ECH_1 PF00378.20 OAJ13128.1 - 8.1e-15 54.8 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Formyl_trans_C PF02911.18 OAJ13128.1 - 0.018 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.19 OAJ13128.1 - 0.07 12.9 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Formyl transferase DnaJ_CXXCXGXG PF00684.19 OAJ13135.1 - 1.6e-05 25.2 3.5 0.0065 16.8 0.2 2.4 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 OAJ13135.1 - 8.3 6.5 7.4 17 5.4 0.4 3.6 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein FAD-oxidase_C PF02913.19 OAJ13137.1 - 1.2e-53 182.3 0.1 4e-53 180.6 0.1 1.7 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ13137.1 - 1.4e-25 89.6 0.0 4.2e-25 88.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Peptidase_C7 PF01830.18 OAJ13137.1 - 0.047 13.1 0.1 0.087 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase C7 family BBE PF08031.12 OAJ13137.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like PQ-loop PF04193.14 OAJ13138.1 - 2.5e-36 123.2 10.1 8.4e-18 63.9 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat Mg_trans_NIPA PF05653.14 OAJ13138.1 - 0.015 14.4 3.9 0.032 13.3 3.5 1.6 1 1 1 2 2 2 0 Magnesium transporter NIPA DUF2781 PF10914.8 OAJ13138.1 - 0.032 14.6 2.8 0.073 13.5 2.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) Form-deh_trans PF09163.11 OAJ13138.1 - 0.039 13.7 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane PrgH PF09480.10 OAJ13138.1 - 0.21 10.8 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Frag1 PF10277.9 OAJ13138.1 - 0.79 9.2 12.1 3.5 7.1 12.0 1.9 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Erf4 PF10256.9 OAJ13139.1 - 1.2e-31 109.2 0.0 1.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.19 OAJ13140.1 - 1.2e-32 111.6 0.2 2.6e-32 110.5 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAJ13140.1 - 3.3e-26 91.7 0.1 6.7e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OAJ13140.1 - 1e-05 25.5 0.1 4.1e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Restriction endonuclease SET PF00856.28 OAJ13141.1 - 2.1e-17 64.1 5.2 9e-17 62.0 0.0 3.3 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAJ13141.1 - 1.6e-13 51.2 6.7 1.6e-13 51.2 6.7 1.8 2 0 0 2 2 2 1 Pre-SET motif Rax2 PF12768.7 OAJ13142.1 - 7.4e-38 130.2 0.3 1.2e-35 122.9 0.0 3.5 4 0 0 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 OAJ13142.1 - 1.1e-14 53.8 0.0 2.2e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ13142.1 - 1.9e-11 43.7 0.0 3.6e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ13142.1 - 1.6e-06 27.7 0.0 3.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ13142.1 - 0.017 15.2 0.0 0.067 13.3 0.0 2.0 2 0 0 2 2 2 0 SH3 domain LapA_dom PF06305.11 OAJ13142.1 - 1.1 9.1 3.2 4.4 7.2 3.2 2.0 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FAD_binding_6 PF00970.24 OAJ13144.1 - 5e-33 113.4 0.0 8.1e-33 112.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ13144.1 - 1.5e-30 106.0 0.0 2.8e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAJ13144.1 - 7.4e-07 29.4 0.0 5.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Adap_comp_sub PF00928.21 OAJ13146.1 - 4.6e-86 288.4 0.0 6e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ13146.1 - 1.3e-05 25.2 0.6 2.5e-05 24.2 0.5 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OAJ13146.1 - 0.026 14.0 0.1 0.039 13.4 0.1 1.4 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain MAM PF00629.23 OAJ13146.1 - 0.093 12.6 0.9 0.24 11.3 0.0 2.1 3 0 0 3 3 3 0 MAM domain, meprin/A5/mu Pectate_lyase_3 PF12708.7 OAJ13156.1 - 1.8e-76 256.8 4.7 4.5e-62 209.7 1.1 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAJ13156.1 - 0.00028 20.5 0.6 0.8 9.4 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAJ13156.1 - 0.3 10.9 4.6 1.5 8.6 0.3 3.2 3 0 0 3 3 3 0 Right handed beta helix region PH PF00169.29 OAJ13157.1 - 2.9e-15 56.6 0.0 2.4e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 OAJ13157.1 - 2.4e-12 46.5 0.1 4.4e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ13157.1 - 1.9e-11 43.4 0.4 3.8e-11 42.4 0.4 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ13157.1 - 1.8e-07 30.7 0.0 3.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ13157.1 - 3.6e-07 30.2 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ13157.1 - 0.00018 21.9 0.1 0.00036 20.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3104 PF11302.8 OAJ13157.1 - 0.054 13.2 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) SAM_Ste50p PF09235.10 OAJ13157.1 - 0.11 12.7 0.1 0.36 11.1 0.1 1.8 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Hus1 PF04005.12 OAJ13158.1 - 8.7e-64 215.4 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein Tfb2 PF03849.14 OAJ13159.1 - 2e-135 451.3 0.0 2.4e-135 451.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAJ13159.1 - 2.6e-23 82.2 0.1 6.4e-23 81.0 0.1 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAJ13159.1 - 0.00056 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prp18 PF02840.15 OAJ13160.1 - 1.4e-60 203.5 0.0 2.1e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 OAJ13160.1 - 9.2e-12 44.3 5.3 2.2e-11 43.1 5.3 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Methyltransf_23 PF13489.6 OAJ13162.1 - 9.7e-20 71.1 0.0 1.9e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ13162.1 - 3.8e-18 65.9 0.0 7.8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ13162.1 - 3e-14 53.5 0.1 9.2e-14 51.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ13162.1 - 9.7e-14 51.9 0.0 2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ13162.1 - 8.6e-13 48.3 0.0 2.3e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ13162.1 - 3.1e-07 30.0 0.0 4.8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ13162.1 - 2.6e-05 23.3 0.0 0.00011 21.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 OAJ13162.1 - 5.4e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OAJ13162.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAJ13162.1 - 0.0031 17.2 0.0 0.035 13.7 0.0 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 OAJ13162.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAJ13162.1 - 0.052 13.1 0.0 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DREV PF05219.12 OAJ13162.1 - 0.097 11.8 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase TPMT PF05724.11 OAJ13162.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 OAJ13162.1 - 0.13 11.9 0.0 0.65 9.6 0.1 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW BIRC6 PF12356.8 OAJ13164.1 - 0.016 14.7 1.4 0.051 13.0 1.4 1.8 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Roughex PF06020.11 OAJ13164.1 - 0.4 9.7 7.2 1.3 8.1 7.2 1.8 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAJ13164.1 - 6.2 6.0 5.7 12 5.1 5.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1681 PF07933.14 OAJ13165.1 - 3.7e-50 169.5 0.0 4.4e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Suf PF05843.14 OAJ13166.1 - 0.0005 20.1 8.0 0.079 12.9 0.1 4.8 4 2 1 6 6 6 1 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAJ13166.1 - 0.0044 17.3 9.0 31 5.3 0.0 8.1 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ13166.1 - 0.0083 16.9 49.2 4.5 8.4 0.0 13.2 12 3 2 14 14 14 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAJ13166.1 - 0.3 11.1 7.7 0.54 10.3 0.2 5.1 7 1 0 8 8 8 0 Mad3/BUB1 homology region 1 GA-like PF17573.2 OAJ13166.1 - 0.32 11.0 4.2 0.88 9.5 4.2 1.8 1 0 0 1 1 1 0 GA-like domain TPR_2 PF07719.17 OAJ13166.1 - 0.33 11.2 17.7 5.8 7.3 0.2 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat FAM176 PF14851.6 OAJ13166.1 - 1.7 8.3 17.5 0.24 11.1 1.8 4.2 4 0 0 4 4 4 0 FAM176 family TPR_6 PF13174.6 OAJ13166.1 - 3.4 8.5 8.8 2e+02 2.9 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat GST_N PF02798.20 OAJ13177.1 - 7e-12 45.5 0.2 1.8e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ13177.1 - 1.7e-09 37.8 0.0 3.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ13177.1 - 2.6e-08 34.2 0.0 4.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ13177.1 - 2.9e-08 33.9 0.0 1.1e-07 32.0 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ13177.1 - 3.1e-06 27.1 0.0 6.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ13177.1 - 7.5e-05 22.9 0.0 0.00023 21.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ13177.1 - 0.049 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MOSC PF03473.17 OAJ13178.1 - 2.8e-21 75.9 0.0 6.4e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAJ13178.1 - 4.2e-09 36.3 0.1 1.1e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OAJ13178.1 - 4e-08 32.6 0.1 0.0023 17.0 0.0 3.5 4 1 0 4 4 4 2 Aminotransferase class-V Toxin_14 PF07829.11 OAJ13178.1 - 0.081 12.9 0.5 0.24 11.4 0.5 1.8 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein HSD3 PF15244.6 OAJ13178.1 - 0.22 11.0 0.5 0.38 10.2 0.5 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 RNase_P_p30 PF01876.16 OAJ13179.1 - 5.2e-39 133.9 0.0 1.9e-37 128.8 0.0 2.7 3 0 0 3 3 3 1 RNase P subunit p30 Trypan_PARP PF05887.11 OAJ13179.1 - 0.26 11.3 2.3 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CRAL_TRIO PF00650.20 OAJ13180.1 - 5.8e-21 74.9 0.0 7.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ13180.1 - 7.7e-07 29.2 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain INCENP_ARK-bind PF03941.15 OAJ13180.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.8 3 0 0 3 3 3 0 Inner centromere protein, ARK binding region UPF0242 PF06785.11 OAJ13181.1 - 0.015 15.4 0.3 0.015 15.4 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc42p PF11544.8 OAJ13181.1 - 0.02 14.9 0.4 0.02 14.9 0.4 1.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF1192 PF06698.11 OAJ13181.1 - 0.074 13.1 0.3 4.8 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) IFT20 PF14931.6 OAJ13181.1 - 0.08 13.1 2.5 0.16 12.2 2.5 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 G_glu_transpept PF01019.21 OAJ13182.1 - 7.2e-137 457.2 0.0 8.3e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2347 PF09804.9 OAJ13183.1 - 1.8e-33 116.4 0.0 2.2e-32 112.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 OAJ13183.1 - 0.001 19.5 0.4 0.02 15.4 0.0 2.5 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAJ13183.1 - 0.0011 17.7 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 Roughex PF06020.11 OAJ13183.1 - 0.46 9.5 3.0 1.1 8.2 3.0 1.6 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAJ13183.1 - 5.7 6.2 7.1 11 5.3 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ13183.1 - 9 5.9 9.3 13 5.4 4.5 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ATG22 PF11700.8 OAJ13184.1 - 2.5e-121 405.6 17.1 2.9e-121 405.4 17.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like SKN1 PF03935.15 OAJ13185.1 - 1.9e-178 594.0 1.0 2.2e-178 593.7 1.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Bac_rhodopsin PF01036.18 OAJ13186.1 - 1.4e-48 165.4 17.9 1.9e-48 165.0 17.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2754 PF10953.8 OAJ13186.1 - 1.3 9.3 6.1 4.8 7.5 6.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Acyltransferase PF01553.21 OAJ13187.1 - 3.1e-15 56.0 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase RPE65 PF03055.15 OAJ13188.1 - 1.5e-97 327.8 0.0 3.1e-97 326.7 0.0 1.5 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein WD40 PF00400.32 OAJ13196.1 - 9.5e-07 29.4 13.3 0.0074 17.1 0.2 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.22 OAJ13196.1 - 0.073 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain DHHA1 PF02272.19 OAJ13196.1 - 0.21 12.0 2.5 0.5 10.8 2.5 1.5 1 0 0 1 1 1 0 DHHA1 domain Zn_clus PF00172.18 OAJ13198.1 - 3.4e-06 27.1 5.8 5.3e-06 26.4 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.20 OAJ13199.1 - 2.5e-18 66.0 0.0 4.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Presenilin PF01080.17 OAJ13199.1 - 0.45 9.2 3.9 0.49 9.1 3.9 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 OAJ13199.1 - 0.56 9.0 6.1 0.56 9.0 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOBP PF15279.6 OAJ13199.1 - 1.3 9.5 10.4 1.6 9.3 10.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PI3K_1B_p101 PF10486.9 OAJ13199.1 - 2.4 5.8 6.8 2.8 5.6 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit EMP24_GP25L PF01105.24 OAJ13200.1 - 3.5e-43 147.7 0.0 4.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAJ13200.1 - 0.052 13.8 0.1 0.084 13.1 0.1 1.3 1 0 0 1 1 1 0 SdrD B-like domain Syndecan PF01034.20 OAJ13200.1 - 0.78 9.7 2.4 0.95 9.4 0.1 2.1 2 0 0 2 2 2 0 Syndecan domain SNARE PF05739.19 OAJ13201.1 - 0.00087 19.2 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 SNARE domain Spectrin PF00435.21 OAJ13201.1 - 0.045 14.2 0.4 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Spectrin repeat DUF3450 PF11932.8 OAJ13201.1 - 0.059 12.7 1.6 0.68 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YjcZ PF13990.6 OAJ13201.1 - 0.079 12.3 0.8 0.18 11.2 0.8 1.5 1 0 0 1 1 1 0 YjcZ-like protein SlyX PF04102.12 OAJ13201.1 - 0.9 10.2 6.8 1.7 9.3 1.3 3.6 3 2 1 4 4 4 0 SlyX SHR3_chaperone PF08229.11 OAJ13203.1 - 0.21 10.5 2.5 0.27 10.2 0.1 2.2 2 2 1 3 3 3 0 ER membrane protein SH3 Hemerythrin PF01814.23 OAJ13205.1 - 1.4e-10 41.9 5.7 1.8e-09 38.3 5.9 1.9 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Acetyltransf_1 PF00583.25 OAJ13214.1 - 3.1e-06 27.4 0.1 5.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ13214.1 - 0.003 18.0 0.1 0.0098 16.3 0.1 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Phage_holin_2_3 PF16080.5 OAJ13215.1 - 0.026 14.3 0.2 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF3262 PF11660.8 OAJ13215.1 - 0.082 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Thymidylat_synt PF00303.19 OAJ13216.1 - 6.2e-106 353.4 0.0 8.5e-106 353.0 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 OAJ13216.1 - 2.5e-36 125.2 0.7 4e-35 121.3 0.7 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) XRCC4 PF06632.12 OAJ13218.1 - 0.092 11.6 6.4 0.15 10.9 6.4 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Pkinase_Tyr PF07714.17 OAJ13219.1 - 1.8e-45 155.3 0.0 2.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAJ13219.1 - 3.4e-45 154.5 0.0 4.7e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OAJ13219.1 - 0.012 14.6 0.5 0.043 12.8 0.5 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ13219.1 - 0.027 13.2 0.3 0.068 11.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAJ13219.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Complex1_LYR PF05347.15 OAJ13220.1 - 0.00051 20.0 0.8 0.0028 17.7 0.8 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Rhodanese PF00581.20 OAJ13220.1 - 0.019 15.5 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_23 PF13489.6 OAJ13220.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain E1-E2_ATPase PF00122.20 OAJ13221.1 - 7.3e-41 139.7 3.8 1.1e-38 132.6 0.1 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 OAJ13221.1 - 1.1e-17 65.0 0.4 2.2e-17 64.1 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ13221.1 - 4.9e-11 42.1 0.0 1.2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ13221.1 - 0.0029 17.4 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ13221.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Ni_hydr_CYTB PF01292.20 OAJ13221.1 - 5.8 6.5 7.5 0.8 9.3 0.2 2.8 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 NUP PF06516.11 OAJ13222.1 - 1e-120 402.7 0.3 1.2e-120 402.5 0.3 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) zf-C3HC4 PF00097.25 OAJ13223.1 - 5.8e-08 32.5 1.4 5.8e-08 32.5 1.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ13223.1 - 4.6e-07 29.8 1.9 4.6e-07 29.8 1.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ13223.1 - 7.8e-07 28.8 6.0 1.1e-06 28.4 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ13223.1 - 8.4e-07 29.2 4.0 2.2e-06 27.9 1.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ13223.1 - 6.7e-06 25.9 4.3 4.5e-05 23.2 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ13223.1 - 7.5e-05 22.6 3.6 8.6e-05 22.4 1.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ13223.1 - 0.00051 20.1 3.9 0.00051 20.1 3.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ13223.1 - 0.024 14.5 6.2 0.29 11.0 2.6 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ13223.1 - 0.079 13.3 1.5 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Velvet PF11754.8 OAJ13235.1 - 2.6e-67 227.4 0.1 4.1e-43 148.1 0.1 2.2 2 0 0 2 2 2 2 Velvet factor DUF3040 PF11239.8 OAJ13236.1 - 0.081 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 OAJ13236.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Rootletin PF15035.6 OAJ13237.1 - 0.042 13.9 0.0 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Aminotran_5 PF00266.19 OAJ13238.1 - 1.1e-28 100.3 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V UAA PF08449.11 OAJ13239.1 - 7.1e-12 45.1 15.7 4e-06 26.3 0.9 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 OAJ13239.1 - 1.2e-05 25.4 27.3 3e-05 24.2 5.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family MccV PF17508.2 OAJ13239.1 - 0.2 12.2 1.5 0.51 10.9 1.2 1.8 1 1 0 1 1 1 0 Microcin V bacteriocin TPT PF03151.16 OAJ13239.1 - 0.63 9.3 18.9 1.1 8.5 0.4 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family PHO4 PF01384.20 OAJ13239.1 - 6.7 5.7 18.2 0.058 12.4 3.7 2.4 1 1 0 2 2 2 0 Phosphate transporter family DUF4097 PF13349.6 OAJ13241.1 - 7.9e-08 31.9 0.8 1.2e-07 31.4 0.8 1.3 1 0 0 1 1 1 1 Putative adhesin PBP_N PF17093.5 OAJ13241.1 - 0.018 15.3 1.0 0.018 15.3 1.0 2.0 2 1 0 2 2 2 0 Penicillin-binding protein N-terminus PUA PF01472.20 OAJ13241.1 - 0.05 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 PUA domain DUF4097 PF13349.6 OAJ13243.1 - 2.5e-05 23.7 0.3 4.3e-05 23.0 0.3 1.3 1 0 0 1 1 1 1 Putative adhesin PBP_N PF17093.5 OAJ13243.1 - 0.0095 16.2 1.2 0.017 15.4 1.2 1.5 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus PUA PF01472.20 OAJ13243.1 - 0.043 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 PUA domain Fungal_trans PF04082.18 OAJ13244.1 - 2e-14 53.3 0.0 3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ13244.1 - 2.8e-06 27.3 9.6 5e-06 26.5 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc80_HEC PF03801.13 OAJ13253.1 - 1.7e-33 115.4 0.0 3.2e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 OAJ13253.1 - 7.5e-12 45.2 2.5 7.5e-12 45.2 2.5 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF5595) DUF4407 PF14362.6 OAJ13253.1 - 0.34 10.2 28.7 0.39 10.0 9.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAJ13253.1 - 3.2 6.6 34.7 0.13 11.1 10.2 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CLP_protease PF00574.23 OAJ13253.1 - 7.7 6.4 7.3 0.94 9.3 0.7 2.5 2 1 1 3 3 3 0 Clp protease MtrG PF04210.13 OAJ13254.1 - 0.2 11.5 0.0 0.71 9.8 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G UBX PF00789.20 OAJ13255.1 - 5.7e-12 45.7 0.0 8.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain Exo_endo_phos PF03372.23 OAJ13256.1 - 3.5e-12 46.3 0.0 8.1e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hemerythrin PF01814.23 OAJ13258.1 - 0.00033 21.3 1.1 0.002 18.8 0.1 2.1 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain ERp29 PF07749.12 OAJ13258.1 - 0.048 14.6 0.0 0.1 13.5 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain ScdA_N PF04405.14 OAJ13258.1 - 0.2 11.3 0.0 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) XPG_N PF00752.17 OAJ13259.1 - 1.7e-25 89.4 0.0 3.7e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ13259.1 - 4.7e-24 84.5 0.1 1.3e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 OAJ13259.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAJ13259.1 - 0.0095 16.5 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold CN_hydrolase PF00795.22 OAJ13260.1 - 4.6e-53 180.2 0.0 5.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.22 OAJ13261.1 - 5.2e-33 112.7 0.0 8.2e-19 67.2 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAJ13261.1 - 1.4e-13 50.8 1.0 6.3e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain YfdX PF10938.8 OAJ13261.1 - 0.03 14.2 0.3 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 YfdX protein LSM PF01423.22 OAJ13262.1 - 9.7e-19 66.8 1.1 1.2e-18 66.5 1.1 1.1 1 0 0 1 1 1 1 LSM domain P2_N PF18628.1 OAJ13262.1 - 0.024 14.4 0.1 0.025 14.3 0.1 1.1 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain Gemin7 PF11095.8 OAJ13262.1 - 0.045 13.6 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Tail_tube PF10618.9 OAJ13262.1 - 0.052 13.4 0.7 0.13 12.1 0.6 1.7 1 1 1 2 2 2 0 Phage tail tube protein Hfq PF17209.3 OAJ13262.1 - 0.073 12.7 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Hfq protein DUF4826 PF16108.5 OAJ13262.1 - 0.17 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) SRP9-21 PF05486.12 OAJ13263.1 - 2.3e-10 40.7 0.6 3.4e-08 33.8 0.6 2.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF2673 PF10880.8 OAJ13273.1 - 0.088 12.9 0.2 0.13 12.4 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) DUF913 PF06025.12 OAJ13274.1 - 8.6e-93 311.2 0.1 8.6e-93 311.2 0.1 7.3 8 1 0 8 8 8 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OAJ13274.1 - 3.2e-89 299.9 1.8 3.2e-89 299.9 1.8 4.7 5 1 0 5 5 5 1 Domain of Unknown Function (DUF908) UBM PF14377.6 OAJ13274.1 - 9e-22 75.8 13.0 3.1e-11 42.3 0.6 3.9 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 OAJ13274.1 - 6.8e-09 35.5 0.2 1.8e-08 34.1 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain NCBP3 PF10309.9 OAJ13275.1 - 7.8e-12 44.9 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 DASH_Spc19 PF08287.11 OAJ13276.1 - 1.6e-25 89.9 2.7 1.6e-25 89.9 2.7 2.3 2 0 0 2 2 2 1 Spc19 Filament PF00038.21 OAJ13276.1 - 0.00056 19.6 1.9 0.0045 16.6 1.9 1.9 1 1 0 1 1 1 1 Intermediate filament protein GCN5L1 PF06320.13 OAJ13276.1 - 0.023 14.8 0.4 0.023 14.8 0.4 3.0 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) BLOC1_2 PF10046.9 OAJ13276.1 - 1.5 9.2 6.8 9.6 6.6 0.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 OAJ13276.1 - 1.7 9.3 4.5 21 5.8 1.1 2.8 2 1 0 2 2 2 0 Initiation control protein YabA TolA_bind_tri PF16331.5 OAJ13276.1 - 4.7 7.4 16.7 0.68 10.0 1.8 3.8 4 0 0 4 4 4 0 TolA binding protein trimerisation ZapB PF06005.12 OAJ13276.1 - 5.8 7.4 15.0 3.2 8.3 1.7 3.4 3 0 0 3 3 3 0 Cell division protein ZapB Tropomyosin_1 PF12718.7 OAJ13276.1 - 6.7 6.9 15.2 9.3 6.4 1.2 2.7 2 1 0 2 2 2 0 Tropomyosin like Oxysterol_BP PF01237.18 OAJ13277.1 - 7.2e-65 219.2 1.7 9.1e-56 189.3 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein FSH1 PF03959.13 OAJ13278.1 - 1.8e-54 184.7 0.0 2.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OAJ13278.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAJ13278.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 OAJ13278.1 - 0.18 11.6 0.1 2 8.2 0.1 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase IGPD PF00475.18 OAJ13279.1 - 3.1e-60 202.7 0.3 4.9e-60 202.0 0.3 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Nucleo_P87 PF07267.11 OAJ13280.1 - 3.6 6.3 18.4 8 5.2 18.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.19 OAJ13291.1 - 1.7e-25 89.4 13.1 2.3e-25 89.0 10.7 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 OAJ13291.1 - 5.6e-23 81.0 0.1 2.6e-22 78.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OAJ13291.1 - 2.5e-21 75.4 0.0 5.1e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P PLDc_2 PF13091.6 OAJ13292.1 - 7.5e-15 55.0 0.0 5.5e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAJ13292.1 - 1.2e-06 28.4 2.9 0.024 14.8 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif G-alpha PF00503.20 OAJ13293.1 - 1.3e-77 261.3 0.0 2.6e-58 197.9 0.0 2.7 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 OAJ13293.1 - 2.4e-09 36.9 0.0 2.5e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ13293.1 - 0.0094 16.3 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ13293.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ13293.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ13293.1 - 0.028 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 OAJ13293.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 OAJ13293.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 OAJ13293.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OAJ13293.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MIT PF04212.18 OAJ13294.1 - 9.3e-08 32.0 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF5008 PF16400.5 OAJ13294.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5008) NUFIP1 PF10453.9 OAJ13295.1 - 3e-10 39.8 0.5 1.3e-09 37.7 0.5 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) LAP1C PF05609.12 OAJ13295.1 - 0.5 9.4 11.8 0.69 8.9 11.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 OAJ13295.1 - 1.1 8.0 9.7 2.1 7.1 9.7 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 OAJ13295.1 - 1.8 6.8 13.9 2.9 6.1 13.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ13295.1 - 5.1 5.2 29.3 7.6 4.6 29.3 1.1 1 0 0 1 1 1 0 Nop14-like family Myosin_head PF00063.21 OAJ13296.1 - 1.4e-236 787.0 3.3 1.7e-236 786.7 3.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OAJ13296.1 - 3.4e-49 167.1 0.0 5.3e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 OAJ13296.1 - 4.1e-11 42.5 0.1 1.2e-10 41.1 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ13296.1 - 2.3e-10 39.9 0.2 4.8e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ13296.1 - 7.2e-07 28.8 0.1 2.7e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_4 PF06347.13 OAJ13296.1 - 0.00085 19.1 0.3 0.0029 17.4 0.3 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain SH3_3 PF08239.11 OAJ13296.1 - 0.0031 17.7 2.0 0.0074 16.5 2.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.6 OAJ13296.1 - 0.04 14.2 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 OAJ13296.1 - 0.07 12.7 0.4 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 OAJ13296.1 - 0.074 13.4 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OAJ13296.1 - 0.19 11.7 0.1 0.41 10.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain PQ-loop PF04193.14 OAJ13309.1 - 1.2e-14 53.8 0.4 1.2e-14 53.8 0.4 1.7 2 0 0 2 2 2 1 PQ loop repeat Herpes_US9 PF06072.11 OAJ13309.1 - 0.058 13.3 0.5 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2407_C PF13373.6 OAJ13312.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF724 PF05266.14 OAJ13313.1 - 0.13 12.1 3.6 0.67 9.8 3.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Aldo_ket_red PF00248.21 OAJ13314.1 - 6.2e-27 94.5 0.0 2.3e-26 92.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.25 OAJ13315.1 - 8.3e-24 84.1 0.1 2e-14 53.5 0.4 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ13315.1 - 1.6e-14 54.0 0.0 8.8e-13 48.4 0.0 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ13315.1 - 2e-06 27.4 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ13315.1 - 0.0021 18.0 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ13315.1 - 0.042 13.2 0.0 0.22 10.9 0.0 2.1 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) LapA_dom PF06305.11 OAJ13316.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF3377 PF11857.8 OAJ13316.1 - 0.25 11.3 0.0 0.65 10.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4834 PF16118.5 OAJ13316.1 - 8.2 7.5 10.2 1.3e+02 3.6 4.9 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Flavin_Reduct PF01613.18 OAJ13317.1 - 2.8e-22 79.4 0.0 3.9e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain ParE_toxin PF05016.15 OAJ13319.1 - 0.099 13.3 2.2 0.23 12.1 0.1 2.5 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Exonuc_VII_L PF02601.15 OAJ13319.1 - 2.2 7.8 7.8 3.7 7.0 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 OAJ13319.1 - 3.5 7.0 15.4 2.5 7.4 13.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) MCM_bind PF09739.9 OAJ13330.1 - 1.8e-08 33.4 1.5 2.1e-08 33.1 1.5 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor CHCH PF06747.13 OAJ13331.1 - 1e-05 25.5 5.4 1.5e-05 25.0 5.4 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 OAJ13331.1 - 2.9e-05 23.7 1.7 4.1e-05 23.2 1.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MTCP1 PF08991.10 OAJ13331.1 - 0.0005 20.2 2.1 0.00084 19.5 2.1 1.4 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COX6B PF02297.17 OAJ13331.1 - 0.024 14.8 2.3 0.034 14.4 2.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAJ13331.1 - 0.2 12.0 3.5 0.37 11.1 3.5 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 EamA PF00892.20 OAJ13332.1 - 1.6e-06 28.3 34.9 0.00057 20.1 5.7 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 OAJ13332.1 - 0.0038 17.0 2.7 0.0038 17.0 2.7 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) DUF1003 PF06210.11 OAJ13332.1 - 0.051 13.7 0.4 0.23 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Peptidase_C13 PF01650.18 OAJ13333.1 - 6.1e-44 150.5 0.3 8.1e-44 150.1 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family Ribosomal_L18_c PF14204.6 OAJ13333.1 - 0.16 12.9 0.1 0.42 11.6 0.1 1.6 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region FGAR-AT_linker PF18072.1 OAJ13335.1 - 0.16 12.5 0.0 5 7.7 0.0 3.1 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF1295 PF06966.12 OAJ13336.1 - 3.1e-42 144.7 0.9 5.4e-42 143.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAJ13336.1 - 0.00014 21.9 0.1 0.00014 21.9 0.1 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 OAJ13336.1 - 0.031 14.7 0.0 0.09 13.2 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ13336.1 - 0.067 13.6 1.6 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase FAD_binding_7 PF03441.14 OAJ13337.1 - 1.1e-73 247.1 0.9 1.7e-73 246.4 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ13337.1 - 1.4e-39 135.7 0.1 2.5e-39 134.9 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Glycophorin_A PF01102.18 OAJ13339.1 - 0.055 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Glycophorin A FAM53 PF15242.6 OAJ13339.1 - 2.2 8.1 6.5 3.3 7.4 6.5 1.2 1 0 0 1 1 1 0 Family of FAM53 His_Phos_2 PF00328.22 OAJ13340.1 - 1.2e-48 166.4 0.0 2.3e-48 165.5 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LRR_4 PF12799.7 OAJ13341.1 - 0.5 10.9 2.7 0.95 10.0 0.6 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-CCHC PF00098.23 OAJ13343.1 - 2.4e-09 36.8 21.3 0.0005 20.0 1.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ13343.1 - 0.00021 20.9 17.4 0.54 10.0 0.3 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ13343.1 - 0.39 10.6 14.2 0.64 9.9 0.1 4.1 4 0 0 4 4 4 0 Zinc knuckle Sporozoite_P67 PF05642.11 OAJ13344.1 - 0.079 11.0 2.5 0.11 10.5 2.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PPI_Ypi1 PF07491.11 OAJ13355.1 - 4e-26 90.6 0.6 4e-26 90.6 0.6 2.3 3 0 0 3 3 3 1 Protein phosphatase inhibitor Gp5_C PF06715.12 OAJ13355.1 - 0.13 12.5 2.3 0.62 10.3 0.9 2.3 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) DUF4695 PF15766.5 OAJ13355.1 - 0.19 12.0 6.0 0.081 13.2 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) CDC45 PF02724.14 OAJ13355.1 - 6.2 5.0 11.4 14 3.9 11.3 1.5 1 1 0 1 1 1 0 CDC45-like protein CitT PF12431.8 OAJ13356.1 - 0.19 12.1 2.3 11 6.5 0.5 3.5 3 0 0 3 3 3 0 Transcriptional regulator MCM_bind PF09739.9 OAJ13357.1 - 1.1e-62 212.4 0.2 1e-51 176.1 0.1 4.5 1 1 1 3 3 3 3 Mini-chromosome maintenance replisome factor Aminotran_5 PF00266.19 OAJ13359.1 - 6.7e-87 291.8 0.0 1e-86 291.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ13359.1 - 0.00011 21.6 0.3 0.00023 20.6 0.3 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAJ13359.1 - 0.09 11.3 0.1 0.22 10.0 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Gpr1_Fun34_YaaH PF01184.19 OAJ13360.1 - 1.7e-40 138.8 15.2 2.1e-40 138.5 15.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Histidinol_dh PF00815.20 OAJ13362.1 - 5e-160 533.0 0.2 1.1e-159 531.9 0.2 1.5 1 1 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAJ13362.1 - 5.8e-21 74.1 0.2 1.1e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAJ13362.1 - 2.8e-13 50.1 1.0 6e-13 49.0 1.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAJ13362.1 - 0.014 15.6 0.2 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Pkinase PF00069.25 OAJ13363.1 - 2.7e-50 171.2 0.0 4.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13363.1 - 1.2e-23 83.7 0.0 3.1e-23 82.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAJ13363.1 - 0.023 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 OAJ13363.1 - 0.033 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAJ13363.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SHQ1 PF04925.15 OAJ13364.1 - 3.9e-23 81.9 0.0 1.7e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein DUF4115 PF13464.6 OAJ13364.1 - 0.027 14.7 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) DASH_Hsk3 PF08227.11 OAJ13365.1 - 1.4e-06 28.6 3.8 2e-06 28.1 3.8 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like WD40 PF00400.32 OAJ13366.1 - 8e-26 89.8 12.2 6.8e-06 26.7 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 OAJ13366.1 - 1.4e-08 33.9 0.4 0.00057 18.6 0.0 4.7 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 OAJ13366.1 - 0.0003 21.0 0.7 1.8 8.9 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RVT_2 PF07727.14 OAJ13378.1 - 4.9e-31 108.2 0.0 6.5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_tran_CTD PF16326.5 OAJ13378.1 - 0.00087 19.5 3.9 0.0014 18.8 0.1 2.8 2 1 0 3 3 2 1 ABC transporter C-terminal domain V_ATPase_I PF01496.19 OAJ13378.1 - 0.021 12.8 2.0 0.022 12.7 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc29 PF17082.5 OAJ13378.1 - 0.025 14.5 10.6 0.3 10.9 2.0 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 Laminin_II PF06009.12 OAJ13378.1 - 0.054 13.5 3.3 0.1 12.6 3.3 1.5 1 1 0 1 1 1 0 Laminin Domain II DivIC PF04977.15 OAJ13378.1 - 0.055 13.2 10.2 0.53 10.1 0.7 3.6 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.11 OAJ13378.1 - 0.11 12.7 19.1 0.95 9.6 19.1 2.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Fzo_mitofusin PF04799.13 OAJ13378.1 - 0.2 11.2 6.2 0.036 13.6 2.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region Csm1_N PF18504.1 OAJ13378.1 - 0.23 11.9 0.3 0.23 11.9 0.3 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF1664 PF07889.12 OAJ13378.1 - 0.33 11.0 8.4 0.24 11.4 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 OAJ13378.1 - 0.45 9.9 17.9 1.3 8.4 5.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 OAJ13378.1 - 0.69 9.2 15.8 1.4 8.2 15.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 OAJ13378.1 - 0.8 10.0 8.1 0.15 12.3 1.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TolA_bind_tri PF16331.5 OAJ13378.1 - 1 9.5 13.5 6.4 6.9 2.7 3.1 1 1 1 2 2 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 OAJ13378.1 - 1.2 9.6 5.1 1.4 9.4 0.5 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.9 OAJ13378.1 - 1.7 8.9 19.9 0.95 9.7 6.7 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OAJ13378.1 - 1.7 8.7 10.5 3.1 7.9 10.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAJ13378.1 - 5.9 5.7 14.4 0.39 9.6 4.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4404 PF14357.6 OAJ13378.1 - 6.9 7.4 8.3 1.1 9.9 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DASH_Spc34 PF08657.10 OAJ13378.1 - 8.4 6.1 13.1 12 5.6 11.0 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 Dimer_Tnp_hAT PF05699.14 OAJ13380.1 - 1.2e-14 53.8 0.2 2.5e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ13380.1 - 0.0015 18.8 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) YL1 PF05764.13 OAJ13382.1 - 2.6 8.1 22.0 0.12 12.4 9.0 2.3 2 0 0 2 2 2 0 YL1 nuclear protein PIF1 PF05970.14 OAJ13385.1 - 5.8e-15 55.3 0.0 7.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 OAJ13385.1 - 6.9e-07 27.6 0.0 8.2e-07 27.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 OAJ13385.1 - 3.2e-05 23.7 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Hydrolase_4 PF12146.8 OAJ13394.1 - 7.7e-10 38.4 0.3 1.5e-09 37.5 0.3 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ13394.1 - 8.1e-09 35.5 0.7 5.8e-07 29.4 0.7 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ13394.1 - 1.1e-07 32.7 0.1 1.4e-07 32.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAJ13394.1 - 0.032 13.8 0.1 3.5 7.1 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family AMP-binding PF00501.28 OAJ13395.1 - 3e-79 266.6 0.0 3.6e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Orn_Arg_deC_N PF02784.16 OAJ13396.1 - 7.3e-26 91.0 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 OAJ13396.1 - 0.0064 16.7 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain ApbA_C PF08546.11 OAJ13398.1 - 1e-23 83.9 0.0 3.3e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ13398.1 - 7e-22 77.7 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.21 OAJ13398.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 OAJ13398.1 - 0.089 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 OAJ13398.1 - 0.14 11.7 0.3 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 OAJ13398.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Phos_pyr_kin PF08543.12 OAJ13401.1 - 1.6e-51 175.1 0.0 2e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase MCLC PF05934.11 OAJ13401.1 - 0.1 11.3 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Sugar_tr PF00083.24 OAJ13402.1 - 2.1e-22 79.6 7.8 2.9e-22 79.2 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ13402.1 - 9.3e-11 41.2 4.9 9.3e-11 41.2 4.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_11 PF08241.12 OAJ13403.1 - 7e-10 39.4 0.0 1.6e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ13403.1 - 3.8e-08 33.9 0.0 1.2e-07 32.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ13403.1 - 9.3e-08 32.1 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ13403.1 - 1.2e-07 32.3 0.0 7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ13403.1 - 0.00021 22.3 0.1 0.0051 17.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ13403.1 - 0.0038 17.0 0.0 0.033 14.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ13403.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 OAJ13403.1 - 0.032 13.9 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.16 OAJ13404.1 - 3.1e-31 108.6 9.7 3.1e-31 108.6 9.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ13404.1 - 2.9e-06 26.4 5.9 9.3e-06 24.8 6.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 OAJ13404.1 - 4.2e-06 26.3 5.2 2e-05 24.1 1.7 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 OAJ13404.1 - 0.00059 18.4 0.3 0.0011 17.5 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 OAJ13404.1 - 0.039 12.7 2.2 0.28 9.9 0.1 2.1 2 0 0 2 2 2 0 LacY proton/sugar symporter MFS_1_like PF12832.7 OAJ13404.1 - 0.5 9.2 4.6 0.14 11.0 0.1 2.0 2 0 0 2 2 2 0 MFS_1 like family Acyl-CoA_dh_1 PF00441.24 OAJ13405.1 - 1.7e-34 119.2 0.3 2.3e-34 118.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ13405.1 - 2.7e-17 62.7 0.1 4.5e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ13405.1 - 1.6e-12 48.1 0.0 6e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ13405.1 - 3.6e-12 46.7 0.1 5.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M48_N PF16491.5 OAJ13407.1 - 1.1e-58 198.2 3.9 1.9e-58 197.3 3.9 1.4 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAJ13407.1 - 4.3e-29 101.7 0.2 6.2e-22 78.3 0.1 3.1 2 1 0 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 OAJ13407.1 - 0.015 14.5 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4538 PF15061.6 OAJ13407.1 - 4.9 7.0 5.9 20 5.0 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4538) Peptidase_M43 PF05572.13 OAJ13408.1 - 3.3e-12 46.6 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 OAJ13408.1 - 5.7e-05 23.3 0.3 0.00027 21.1 0.2 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 OAJ13408.1 - 0.00091 19.7 0.0 0.0022 18.5 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ13408.1 - 0.049 13.5 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 OAJ13408.1 - 0.054 12.7 0.1 0.084 12.1 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Tyrosinase PF00264.20 OAJ13420.1 - 9.5e-40 137.2 0.0 1.3e-39 136.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase TPR_10 PF13374.6 OAJ13421.1 - 1.1e-10 41.0 30.6 0.016 15.0 0.2 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ13421.1 - 3.6e-08 33.6 34.4 0.16 12.3 0.7 7.9 6 2 1 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13421.1 - 6.7e-05 22.7 8.3 3.3 8.1 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13421.1 - 0.00041 20.3 10.5 8.4 6.9 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ13421.1 - 0.0021 18.1 16.5 0.069 13.2 1.7 5.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 OAJ13421.1 - 0.015 15.4 9.7 0.26 11.3 0.4 4.1 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 OAJ13421.1 - 0.089 12.6 4.0 27 4.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SMBP PF16785.5 OAJ13421.1 - 3.2 8.0 6.7 1.5 9.1 2.7 2.5 2 0 0 2 2 2 0 Small metal-binding protein Tyrosinase PF00264.20 OAJ13422.1 - 1.4e-30 107.3 0.0 3e-30 106.2 0.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ13423.1 - 9.4e-39 134.0 0.7 1.4e-38 133.5 0.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PTPlike_phytase PF14566.6 OAJ13424.1 - 7e-18 65.2 0.5 1.8e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Inositol hexakisphosphate UPF0139 PF03669.13 OAJ13433.1 - 0.0051 16.7 0.0 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Spike_torovirin PF17072.5 OAJ13433.1 - 0.011 12.9 0.0 0.013 12.6 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Prominin PF05478.11 OAJ13433.1 - 0.33 8.8 0.2 0.37 8.7 0.2 1.0 1 0 0 1 1 1 0 Prominin Hid1 PF12722.7 OAJ13434.1 - 6.1e-137 458.0 0.0 2.8e-116 389.6 0.0 2.9 2 1 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAJ13434.1 - 5.6e-68 229.9 0.0 8.2e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Apolipoprotein PF01442.18 OAJ13435.1 - 0.00019 21.3 3.2 0.00023 21.1 3.2 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.11 OAJ13435.1 - 0.0044 16.4 0.9 0.0052 16.2 0.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF5082 PF16888.5 OAJ13435.1 - 0.0065 16.7 1.3 0.011 16.0 1.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Phasin PF05597.11 OAJ13435.1 - 0.26 11.3 6.4 0.35 10.9 2.4 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MRFAP1 PF15155.6 OAJ13435.1 - 1.7 9.2 6.1 0.64 10.6 2.6 1.8 1 1 1 2 2 2 0 MORF4 family-associated protein1 DUF883 PF05957.13 OAJ13435.1 - 2.8 8.6 11.5 3.3 8.4 5.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phage_HK97_TLTM PF06120.11 OAJ13435.1 - 2.8 7.1 10.6 13 4.8 10.6 1.8 1 1 0 1 1 1 0 Tail length tape measure protein Mpv17_PMP22 PF04117.12 OAJ13436.1 - 1.1e-23 83.2 0.3 1.7e-23 82.6 0.3 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 OAJ13437.1 - 1e-07 32.0 10.9 1.7e-07 31.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-4CXXC_R1 PF10497.9 OAJ13439.1 - 6.7e-08 32.7 11.7 1.3e-07 31.8 11.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L44 PF00935.19 OAJ13439.1 - 0.23 11.9 1.0 0.83 10.2 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L44 FYVE_2 PF02318.16 OAJ13439.1 - 6.8 6.9 11.6 25 5.1 11.7 1.8 1 1 0 1 1 1 0 FYVE-type zinc finger C5-epim_C PF06662.13 OAJ13440.1 - 0.0047 16.4 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus DUF4173 PF13777.6 OAJ13440.1 - 2.9 7.3 11.2 2.1 7.7 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) Arm PF00514.23 OAJ13441.1 - 2.4 8.3 7.0 15 5.8 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat MFS_1 PF07690.16 OAJ13442.1 - 5.2e-43 147.3 20.4 1.1e-38 133.1 6.1 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ13442.1 - 2.5e-10 39.8 0.2 2.5e-10 39.8 0.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter UPF0242 PF06785.11 OAJ13442.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus OATP PF03137.20 OAJ13442.1 - 0.24 9.7 9.4 0.044 12.1 2.3 3.0 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2207 PF09972.9 OAJ13442.1 - 8.7 5.0 9.3 3 6.5 1.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cyclase PF04199.13 OAJ13450.1 - 1.8e-13 50.9 0.0 3.7e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Pneumo_att_G PF05539.11 OAJ13450.1 - 3.7 7.1 4.7 5.6 6.5 4.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G XRN_M PF17846.1 OAJ13451.1 - 1.7e-143 478.8 0.0 1.7e-106 356.9 0.0 2.3 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 OAJ13451.1 - 3.3e-100 334.5 0.0 7.2e-100 333.4 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 OAJ13451.1 - 0.00015 21.7 3.5 0.00034 20.5 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ13451.1 - 0.64 10.0 3.0 1.2 9.1 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle FAD_binding_4 PF01565.23 OAJ13452.1 - 7.8e-18 64.6 1.3 1.5e-17 63.6 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ13452.1 - 7.8e-05 22.7 0.7 0.00021 21.3 0.7 1.7 1 0 0 1 1 1 1 Berberine and berberine like PDR_CDR PF06422.12 OAJ13452.1 - 0.038 13.9 0.2 0.12 12.3 0.2 1.8 1 0 0 1 1 1 0 CDR ABC transporter AMP-binding PF00501.28 OAJ13453.1 - 1.4e-79 267.7 0.0 8.1e-79 265.2 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ13453.1 - 4.5e-08 33.9 0.0 1.4e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 OAJ13454.1 - 1e-37 129.5 0.2 1.4e-37 129.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ13454.1 - 2.4e-29 102.6 0.3 3.8e-29 101.9 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ13454.1 - 7e-10 39.1 0.6 2.4e-09 37.3 0.6 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 OAJ13454.1 - 0.011 16.4 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 OAJ13454.1 - 0.016 14.6 0.3 0.045 13.2 0.1 1.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAJ13454.1 - 0.042 13.0 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MmoB_DmpM PF02406.17 OAJ13454.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 MmoB/DmpM family CSN7a_helixI PF18392.1 OAJ13455.1 - 8.4e-07 28.8 0.4 1.3e-06 28.2 0.4 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 OAJ13455.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 PCI domain DUF3767 PF12597.8 OAJ13456.1 - 9.2e-28 96.0 0.2 1.1e-27 95.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DIL PF01843.19 OAJ13457.1 - 1.8e-26 92.4 1.1 3.8e-26 91.4 1.1 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 OAJ13457.1 - 1.8e-11 44.5 0.0 5.5e-10 39.7 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ13457.1 - 2.4e-11 43.9 0.1 2.6e-09 37.4 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ13457.1 - 3.4e-11 42.3 0.0 0.00027 21.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAJ13457.1 - 1.8e-07 31.3 0.0 5.7e-05 23.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ13457.1 - 5.7e-07 29.7 0.0 0.0041 17.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SPT16 PF08644.11 OAJ13457.1 - 0.086 13.0 1.3 0.17 12.1 1.3 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) SQHop_cyclase_N PF13249.6 OAJ13457.1 - 0.48 9.5 2.5 0.39 9.8 0.5 1.7 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain UPF0061 PF02696.14 OAJ13458.1 - 4.7e-88 296.0 0.0 1.1e-87 294.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Nop16 PF09420.10 OAJ13471.1 - 6.4e-52 176.6 1.0 7.3e-52 176.4 1.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Peptidase_S3 PF00944.19 OAJ13471.1 - 0.035 13.9 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Alphavirus core protein Msap1 PF17077.5 OAJ13471.1 - 0.12 11.6 0.7 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Mitotic spindle associated protein SHE1 Lin-8 PF03353.15 OAJ13472.1 - 9 5.8 12.9 11 5.5 7.8 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Mannosidase_ig PF17786.1 OAJ13473.1 - 3e-09 37.4 1.3 7.8e-08 32.8 0.3 2.7 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAJ13473.1 - 4.4e-09 36.0 0.0 1.4e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 OAJ13473.1 - 0.1 13.3 0.0 1.1 10.0 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolases family 2 Nop PF01798.18 OAJ13474.1 - 2.6e-81 272.5 0.2 2.6e-81 272.5 0.2 1.8 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ13474.1 - 2.5e-10 40.6 0.0 8.1e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Pkinase PF00069.25 OAJ13475.1 - 1.2e-59 201.9 0.0 9.5e-40 136.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13475.1 - 2.2e-26 92.7 0.0 1.7e-21 76.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAJ13475.1 - 1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAJ13475.1 - 1.4e-06 27.8 0.1 0.00076 18.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAJ13475.1 - 0.0011 18.9 0.0 0.01 15.8 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family OKR_DC_1_N PF03709.15 OAJ13475.1 - 0.0051 17.1 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Kdo PF06293.14 OAJ13475.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OAJ13475.1 - 0.049 12.7 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 OAJ13475.1 - 0.056 14.2 0.1 0.62 10.8 0.1 3.1 1 0 0 1 1 1 0 Protein kinase C terminal domain FTA2 PF13095.6 OAJ13475.1 - 0.071 12.7 0.2 1.6 8.3 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_4 PF08448.10 OAJ13475.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold zf-Sec23_Sec24 PF04810.15 OAJ13476.1 - 0.1 12.6 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Asp PF00026.23 OAJ13488.1 - 2.6e-24 86.2 0.0 3.5e-19 69.4 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ13488.1 - 0.0042 17.3 0.0 0.0097 16.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 OAJ13489.1 - 7.8e-53 179.9 4.9 1.5e-52 179.0 4.9 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ13489.1 - 7.4e-07 29.6 2.4 0.0059 16.9 0.0 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ13489.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Torus PF16131.5 OAJ13491.1 - 7.8e-07 29.8 0.0 3.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 OAJ13491.1 - 6.4e-06 26.0 3.1 1.8e-05 24.6 3.1 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 OAJ13491.1 - 9.5e-06 25.3 0.0 5.6e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ13491.1 - 0.00028 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif FYVE PF01363.21 OAJ13491.1 - 0.012 15.8 1.8 0.013 15.6 0.2 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_3 PF15663.5 OAJ13491.1 - 0.012 15.8 0.1 0.036 14.3 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 OAJ13491.1 - 0.036 14.0 1.2 0.036 14.0 1.2 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Limkain-b1 PF11608.8 OAJ13491.1 - 0.13 12.4 0.3 0.6 10.2 0.2 2.3 2 1 0 2 2 2 0 Limkain b1 zf-CCCH_2 PF14608.6 OAJ13491.1 - 2.7 8.6 5.6 0.91 10.1 2.3 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger MA3 PF02847.17 OAJ13492.1 - 4.1e-30 104.1 0.3 7.4e-30 103.2 0.3 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 OAJ13492.1 - 2.7e-10 40.3 0.1 6.4e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain FAM176 PF14851.6 OAJ13492.1 - 0.26 11.0 9.3 8.4 6.1 5.1 3.3 3 0 0 3 3 3 0 FAM176 family DNA_pol_phi PF04931.13 OAJ13492.1 - 5.9 4.9 17.2 1.3 7.1 11.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi Asp PF00026.23 OAJ13494.1 - 6e-46 157.3 0.0 1.2e-45 156.3 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ13494.1 - 4.5e-08 33.5 0.6 6.7e-05 23.2 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ13494.1 - 0.071 12.9 0.0 3.1 7.5 0.1 2.4 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Abhydrolase_1 PF00561.20 OAJ13495.1 - 1.4e-28 100.2 0.0 2.5e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ13495.1 - 1.1e-10 41.2 0.0 5.5e-08 32.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ13495.1 - 1.9e-10 41.8 1.9 1.9e-10 41.8 1.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAJ13495.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 OAJ13495.1 - 0.26 10.0 0.0 0.38 9.5 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Zn_clus PF00172.18 OAJ13496.1 - 9.9e-05 22.4 9.4 0.00017 21.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 OAJ13506.1 - 5.4e-41 140.9 15.9 5.4e-41 140.9 15.9 2.9 2 1 0 2 2 2 1 ZIP Zinc transporter Hydrolase_4 PF12146.8 OAJ13507.1 - 2.1e-13 50.1 0.0 8.9e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ13507.1 - 6.9e-13 48.8 0.0 1.1e-08 35.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ13507.1 - 1.1e-10 42.5 0.1 1.5e-10 42.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAJ13507.1 - 3.4e-10 39.8 0.0 7.6e-08 32.1 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 OAJ13507.1 - 3.9e-10 38.9 0.0 9.9e-06 24.4 0.0 2.9 2 1 0 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 OAJ13507.1 - 5.8e-10 39.2 0.0 8.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 OAJ13507.1 - 4.9e-08 32.8 0.0 4.8e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAJ13507.1 - 1.6e-05 25.0 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OAJ13507.1 - 0.00085 19.0 0.1 0.058 13.0 0.1 2.1 2 0 0 2 2 2 1 Putative esterase DUF1100 PF06500.11 OAJ13507.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) PAF-AH_p_II PF03403.13 OAJ13507.1 - 0.0058 15.2 0.0 1 7.8 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S28 PF05577.12 OAJ13507.1 - 0.02 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_3 PF07859.13 OAJ13507.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DEAD PF00270.29 OAJ13508.1 - 4.3e-40 137.4 0.1 1.2e-39 135.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ13508.1 - 6.6e-22 78.0 0.0 3.6e-21 75.6 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ13508.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAJ13508.1 - 0.0017 18.1 1.2 0.26 11.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain HRXXH PF13933.6 OAJ13509.1 - 6.8e-78 261.6 0.0 1e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family SMK-1 PF04802.15 OAJ13517.1 - 3.8e-77 258.4 1.9 8.4e-77 257.3 1.9 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Cys_Met_Meta_PP PF01053.20 OAJ13518.1 - 2.1e-130 434.7 0.0 3.7e-130 433.9 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OAJ13518.1 - 6.1e-06 25.0 0.0 8.7e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OAJ13518.1 - 0.0003 19.9 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ13518.1 - 0.036 13.2 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PUF PF00806.19 OAJ13520.1 - 1.5e-59 194.4 15.9 5e-08 32.2 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LOB PF03195.14 OAJ13520.1 - 0.04 14.5 0.2 6.5 7.4 0.0 3.4 2 1 1 4 4 4 0 Lateral organ boundaries (LOB) domain RA PF00788.23 OAJ13520.1 - 0.051 14.2 0.2 0.72 10.5 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Glyco_hydro_79C PF16862.5 OAJ13522.1 - 1.1e-15 58.4 1.0 3.3e-15 56.8 1.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF4336 PF14234.6 OAJ13523.1 - 2.5e-05 23.6 0.0 0.03 13.5 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Heme_oxygenase PF01126.20 OAJ13524.1 - 1.8e-09 37.7 0.0 1.5e-07 31.4 0.0 2.9 3 0 0 3 3 3 1 Heme oxygenase FAD-SLDH PF12318.8 OAJ13524.1 - 0.24 11.5 2.4 0.9 9.6 0.1 2.8 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase RGS12_usC PF16612.5 OAJ13524.1 - 2.3 8.7 11.6 0.11 13.0 2.5 2.5 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 Sybindin PF04099.12 OAJ13525.1 - 1.4e-07 31.6 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Sybindin-like family MerC PF03203.14 OAJ13526.1 - 8.7 6.8 8.2 36 4.8 3.7 3.4 2 1 0 3 3 3 0 MerC mercury resistance protein Cpn60_TCP1 PF00118.24 OAJ13535.1 - 2.7e-145 484.8 14.1 1.4e-92 310.9 5.4 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family RGS PF00615.19 OAJ13536.1 - 1.1e-11 45.0 0.0 1.1e-07 32.2 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Sdh_cyt PF01127.22 OAJ13537.1 - 1.2e-23 83.4 3.6 1.8e-23 82.8 3.6 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Phage_holin_2_4 PF16082.5 OAJ13537.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3450 PF11932.8 OAJ13537.1 - 0.12 11.7 0.4 0.16 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Methyltransf_23 PF13489.6 OAJ13538.1 - 0.00073 19.4 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Nop14 PF04147.12 OAJ13538.1 - 0.25 9.5 1.0 0.46 8.6 1.0 1.3 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ13538.1 - 5.6 6.2 9.3 11 5.3 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3808 PF10300.9 OAJ13539.1 - 1.4e-75 254.9 0.0 2.5e-75 254.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 OAJ13539.1 - 6.2e-31 107.3 0.0 1.1e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ13539.1 - 1.9e-12 47.2 0.8 6e-12 45.6 0.8 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ13539.1 - 4.8e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TelA PF05816.11 OAJ13539.1 - 0.067 12.2 0.2 0.17 10.9 0.2 1.6 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) TPR_8 PF13181.6 OAJ13539.1 - 0.24 11.7 2.8 0.47 10.8 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ13539.1 - 0.39 11.5 1.9 43 5.0 0.5 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ13539.1 - 0.46 10.4 7.2 1.2 9.1 1.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ13539.1 - 0.6 10.3 5.9 8.3 6.7 0.7 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13539.1 - 1.3 9.3 14.9 24 5.4 1.7 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ13539.1 - 2.7 8.4 5.5 4.3 7.7 2.3 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.23 OAJ13540.1 - 2.8e-13 49.9 0.1 5.8e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAJ13540.1 - 1.7e-05 24.8 0.6 7.9e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAJ13540.1 - 0.0001 22.1 0.0 0.006 16.4 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase AAA_18 PF13238.6 OAJ13541.1 - 1.3e-24 87.2 0.0 4.5e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ13541.1 - 0.0032 17.6 0.6 0.69 10.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ13541.1 - 0.037 14.3 2.1 0.04 14.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAJ13541.1 - 0.041 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OAJ13541.1 - 0.071 13.5 0.1 0.12 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 OAJ13541.1 - 0.078 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ADK PF00406.22 OAJ13541.1 - 0.083 13.0 0.1 12 6.0 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase FtsK_SpoIIIE PF01580.18 OAJ13541.1 - 0.11 11.8 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 OAJ13541.1 - 0.12 12.8 0.8 0.29 11.6 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ13541.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF383 PF04063.14 OAJ13542.1 - 4.1e-48 163.6 0.0 3.3e-47 160.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAJ13542.1 - 1.3e-17 63.3 2.4 3.2e-17 62.1 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF1771 PF08590.10 OAJ13542.1 - 0.12 12.7 4.7 0.31 11.5 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DUF883 PF05957.13 OAJ13542.1 - 1.1 9.9 8.1 0.57 10.8 4.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ku_C PF03730.14 OAJ13542.1 - 2.5 8.8 8.8 0.46 11.2 3.6 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm His_Phos_1 PF00300.22 OAJ13543.1 - 4.6e-18 65.6 0.0 7.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SVIP PF15811.5 OAJ13543.1 - 0.32 11.5 8.8 0.094 13.2 5.7 1.8 2 0 0 2 2 2 0 Small VCP/p97-interacting protein DUF4048 PF13257.6 OAJ13553.1 - 0.28 11.0 8.8 0.043 13.7 5.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) DUF3053 PF11254.8 OAJ13555.1 - 0.011 15.4 4.6 0.011 15.4 4.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3053) DUF3818 PF12825.7 OAJ13555.1 - 0.045 12.8 8.0 0.016 14.2 5.5 1.5 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) YTH PF04146.15 OAJ13557.1 - 1.3e-34 119.5 0.0 2.9e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 YT521-B-like domain HECT_2 PF09814.9 OAJ13558.1 - 6.9e-32 110.7 0.0 8e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SRP14 PF02290.15 OAJ13560.1 - 3.7e-14 52.8 0.5 8e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle 14kD protein AMP-binding PF00501.28 OAJ13562.1 - 0.11 11.1 0.0 0.23 10.0 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme Wzy_C PF04932.15 OAJ13562.1 - 0.32 10.6 0.0 0.32 10.6 0.0 2.5 2 1 0 2 2 2 0 O-Antigen ligase DUF962 PF06127.11 OAJ13562.1 - 2.3 8.3 4.8 6.1 7.0 0.1 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF962) Spb1_C PF07780.12 OAJ13563.1 - 7.5e-72 241.4 40.7 7.5e-72 241.4 40.7 4.1 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAJ13563.1 - 1.3e-55 188.3 0.1 5.4e-55 186.2 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAJ13563.1 - 1.5e-38 132.2 11.0 1.5e-38 132.2 11.0 5.8 6 0 0 6 6 6 2 Domain of unknown function (DUF3381) HSP70 PF00012.20 OAJ13575.1 - 0.0025 16.1 0.1 0.0061 14.8 0.1 1.6 2 0 0 2 2 2 1 Hsp70 protein ZZ PF00569.17 OAJ13576.1 - 7.1e-18 64.2 24.3 2.3e-09 36.9 6.2 3.3 3 0 0 3 3 3 2 Zinc finger, ZZ type zinc_ribbon_4 PF13717.6 OAJ13576.1 - 0.0044 16.9 1.3 0.0044 16.9 1.3 3.4 5 0 0 5 5 5 1 zinc-ribbon domain C1_2 PF03107.16 OAJ13576.1 - 7.7 6.9 25.2 0.44 10.9 3.1 3.1 4 0 0 4 4 4 0 C1 domain HSP70 PF00012.20 OAJ13578.1 - 0.00032 19.0 0.1 0.33 9.1 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein MLANA PF14991.6 OAJ13579.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A SKG6 PF08693.10 OAJ13579.1 - 0.015 14.7 1.1 0.034 13.6 1.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 OAJ13579.1 - 0.063 14.2 0.0 0.11 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 OAJ13583.1 - 0.0028 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Herpes_gE PF02480.16 OAJ13583.1 - 0.066 11.9 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 OAJ13583.1 - 0.15 13.0 0.0 0.32 11.9 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RhoGEF PF00621.20 OAJ13592.1 - 3.9e-29 102.2 0.0 5e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain FANCAA PF15146.6 OAJ13592.1 - 0.014 14.6 0.7 0.023 13.8 0.7 1.2 1 0 0 1 1 1 0 Fanconi anemia-associated 3-HAO PF06052.12 OAJ13593.1 - 3.7e-58 195.5 0.0 4.2e-58 195.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OAJ13593.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAJ13593.1 - 0.0079 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Cupin adh_short PF00106.25 OAJ13594.1 - 2.5e-21 76.0 0.4 2e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ13594.1 - 3.9e-11 43.0 0.0 1.1e-10 41.5 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ13594.1 - 2e-06 27.9 0.1 3e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ13594.1 - 0.0058 16.1 0.1 0.015 14.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ13594.1 - 0.01 15.3 0.6 0.064 12.7 0.2 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase GATA PF00320.27 OAJ13595.1 - 2.9e-11 42.8 12.1 9.4e-06 25.1 2.5 2.4 2 0 0 2 2 2 2 GATA zinc finger Spt20 PF12090.8 OAJ13595.1 - 0.00071 19.3 16.0 0.00071 19.3 16.0 3.1 3 0 0 3 3 3 2 Spt20 family Zn-ribbon_8 PF09723.10 OAJ13595.1 - 0.0028 17.8 0.4 3 8.0 0.0 2.5 2 0 0 2 2 2 2 Zinc ribbon domain XRCC4 PF06632.12 OAJ13595.1 - 0.057 12.3 3.2 0.12 11.3 3.2 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Vps36-NZF-N PF16988.5 OAJ13595.1 - 0.26 10.7 6.2 3.6 7.0 0.5 3.2 2 2 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FHIPEP PF00771.20 OAJ13595.1 - 2.1 6.7 3.3 3.4 6.0 3.3 1.2 1 0 0 1 1 1 0 FHIPEP family EPL1 PF10513.9 OAJ13595.1 - 4.4 7.7 19.7 0.092 13.1 1.7 3.2 3 0 0 3 3 3 0 Enhancer of polycomb-like GalP_UDP_transf PF01087.22 OAJ13596.1 - 1.2e-59 201.8 0.0 2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAJ13596.1 - 2.5e-43 147.7 0.0 9.4e-23 80.8 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 OAJ13596.1 - 0.018 13.8 0.3 3.8 6.2 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DcpS_C PF11969.8 OAJ13596.1 - 0.057 13.9 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ13596.1 - 0.099 13.4 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 HIT domain His_Phos_1 PF00300.22 OAJ13598.1 - 6.1e-39 133.7 0.0 7.2e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.18 OAJ13599.1 - 8.3e-56 188.7 1.1 1.4e-55 188.0 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ13599.1 - 1.3e-34 118.7 0.0 3.6e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 OAJ13599.1 - 0.0019 18.2 0.2 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 OAJ13599.1 - 0.0022 18.3 0.2 0.0057 16.9 0.2 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1188 PF06690.11 OAJ13599.1 - 0.0075 15.8 0.3 0.019 14.5 0.1 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 OAJ13599.1 - 0.016 14.8 0.5 0.05 13.2 0.5 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Esterase_phd PF10503.9 OAJ13599.1 - 0.026 14.0 0.9 0.042 13.3 0.9 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase NAD_binding_2 PF03446.15 OAJ13599.1 - 0.043 14.0 1.9 0.25 11.5 1.9 2.1 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rrf2 PF02082.20 OAJ13599.1 - 0.058 13.7 0.3 28 5.1 0.0 3.3 4 0 0 4 4 4 0 Transcriptional regulator Shikimate_DH PF01488.20 OAJ13599.1 - 0.068 13.2 1.4 0.53 10.3 0.2 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 OAJ13599.1 - 0.12 12.5 1.1 0.47 10.6 0.6 2.3 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4632 PF15451.6 OAJ13600.1 - 0.011 15.8 0.0 0.064 13.3 0.0 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) PH PF00169.29 OAJ13609.1 - 5.7e-08 33.2 0.1 0.011 16.2 0.1 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OAJ13609.1 - 3.6e-07 30.6 0.3 0.0045 17.4 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OAJ13609.1 - 0.13 12.7 0.3 5.5 7.5 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 OAJ13610.1 - 8.5e-38 130.2 31.0 1.8e-37 129.1 31.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ13610.1 - 4.3e-10 38.7 19.8 1.2e-09 37.1 19.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ13610.1 - 1.2e-05 24.4 19.9 1.2e-05 24.4 19.9 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ13611.1 - 5.2e-41 140.7 34.3 5.2e-41 140.7 34.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ13611.1 - 2.6e-15 55.9 14.7 3.6e-15 55.4 14.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM154 PF15102.6 OAJ13611.1 - 0.023 14.6 0.1 0.023 14.6 0.1 2.2 2 1 0 2 2 2 0 TMEM154 protein family TPR_12 PF13424.6 OAJ13613.1 - 3.5e-09 36.8 11.2 0.0005 20.3 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ13613.1 - 5.4e-06 26.1 9.2 0.18 11.7 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13613.1 - 0.00052 19.9 3.3 0.71 10.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13613.1 - 0.0023 18.0 0.6 0.19 12.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Baculo_gp41 PF04700.12 OAJ13613.1 - 0.042 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region TPR_4 PF07721.14 OAJ13613.1 - 0.065 13.9 6.4 2.3 9.1 0.2 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ13613.1 - 0.18 12.7 8.7 0.88 10.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ13613.1 - 0.2 11.7 1.3 5.1 7.4 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 OAJ13614.1 - 0.083 12.7 6.6 0.67 9.7 0.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OAJ13614.1 - 7.6 6.2 9.6 1.9 8.1 1.0 2.7 3 0 0 3 3 3 0 FAM176 family MTP18 PF10558.9 OAJ13615.1 - 3e-59 199.8 0.6 9.6e-59 198.2 0.6 1.8 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) CwsA PF10814.8 OAJ13615.1 - 0.57 10.4 7.8 0.36 11.0 1.3 2.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA AhpC-TSA PF00578.21 OAJ13616.1 - 1.9e-23 82.7 0.0 3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ13616.1 - 1.8e-08 34.2 0.0 3.4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin Histone PF00125.24 OAJ13628.1 - 1e-14 55.0 0.0 1.4e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAJ13628.1 - 3.3e-09 36.3 0.2 5.4e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAJ13628.1 - 5e-06 26.7 0.0 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAC3 PF10178.9 OAJ13629.1 - 0.029 14.5 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 Macoilin PF09726.9 OAJ13629.1 - 0.056 12.0 4.0 0.073 11.6 4.0 1.0 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 OAJ13629.1 - 0.31 10.3 14.3 0.46 9.8 14.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ13629.1 - 0.63 8.2 12.3 0.85 7.8 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 OAJ13629.1 - 1.9 7.5 15.7 3.2 6.8 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 OAJ13629.1 - 2.3 7.5 14.3 3.2 7.1 14.3 1.1 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 OAJ13629.1 - 3.3 7.0 5.6 1.5 8.2 3.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) GREB1 PF15782.5 OAJ13629.1 - 3.6 4.6 5.5 4.4 4.3 5.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TRAP_alpha PF03896.16 OAJ13629.1 - 5.1 6.2 8.0 7.6 5.7 8.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 OAJ13629.1 - 5.9 4.9 17.4 8.1 4.4 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Prefoldin_2 PF01920.20 OAJ13630.1 - 7.7e-21 74.1 1.6 1.1e-20 73.6 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mei5 PF10376.9 OAJ13630.1 - 0.014 15.3 1.5 0.017 15.0 1.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF4407 PF14362.6 OAJ13630.1 - 0.019 14.3 3.3 0.028 13.8 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MSA-2c PF12238.8 OAJ13630.1 - 0.035 14.1 0.2 0.061 13.3 0.1 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Prefoldin PF02996.17 OAJ13630.1 - 0.06 13.3 2.9 0.16 11.9 2.9 1.7 1 1 0 1 1 1 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 OAJ13630.1 - 0.89 9.6 9.5 1.5 8.9 5.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GTA_holin_3TM PF11351.8 OAJ13630.1 - 1.9 9.1 5.6 0.75 10.3 3.1 1.6 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release Spc7 PF08317.11 OAJ13630.1 - 3.1 6.6 8.1 13 4.6 3.7 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Tetraspanin PF00335.20 OAJ13631.1 - 6.2e-07 29.4 8.8 9.6e-07 28.7 8.8 1.3 1 0 0 1 1 1 1 Tetraspanin family FA_desaturase PF00487.24 OAJ13631.1 - 0.0035 17.2 0.7 0.0062 16.4 0.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Wzy_C PF04932.15 OAJ13631.1 - 9.3 5.9 10.3 5.3 6.6 0.7 2.3 1 1 1 2 2 2 0 O-Antigen ligase RSN1_7TM PF02714.15 OAJ13632.1 - 1.8e-57 194.8 21.3 2.9e-57 194.1 21.3 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAJ13632.1 - 3.3e-22 78.9 0.4 2e-21 76.4 0.0 2.6 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAJ13632.1 - 9.3e-21 74.8 0.1 4.4e-18 66.1 0.1 2.5 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter BSP_II PF05432.11 OAJ13632.1 - 9.8 5.8 8.2 0.89 9.2 2.6 2.0 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) EF-hand_4 PF12763.7 OAJ13633.1 - 1.2e-34 118.4 0.0 2.9e-15 56.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAJ13633.1 - 0.00015 22.2 0.0 0.21 12.1 0.0 3.6 3 1 1 4 4 3 2 EF-hand domain pair Macoilin PF09726.9 OAJ13633.1 - 0.0032 16.1 8.9 0.0045 15.6 8.9 1.1 1 0 0 1 1 1 1 Macoilin family DUF4366 PF14283.6 OAJ13633.1 - 0.22 11.6 1.4 11 6.1 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) SKA1 PF07160.12 OAJ13633.1 - 0.73 9.6 7.7 1.4 8.7 7.7 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FapA PF03961.13 OAJ13633.1 - 1.9 7.0 6.0 3 6.4 6.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Synaptobrevin PF00957.21 OAJ13633.1 - 2.1 8.2 4.3 3.9 7.3 4.3 1.3 1 0 0 1 1 1 0 Synaptobrevin PIEZO PF15917.5 OAJ13633.1 - 3 7.2 5.2 6.6 6.1 5.2 1.5 1 0 0 1 1 1 0 Piezo Cnn_1N PF07989.11 OAJ13633.1 - 3.2 8.0 9.6 4.4 7.5 8.6 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 OAJ13633.1 - 4.1 8.1 8.9 4.3 8.0 5.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA zf-C4H2 PF10146.9 OAJ13633.1 - 5.1 7.3 11.0 0.39 11.0 5.6 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein Golgin_A5 PF09787.9 OAJ13633.1 - 7.8 5.9 17.0 9 5.7 16.1 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 Nup54 PF13874.6 OAJ13633.1 - 8.5 6.5 11.6 28 4.8 11.6 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 HA2 PF04408.23 OAJ13634.1 - 1.3e-23 83.3 0.0 1.5e-22 79.9 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ13634.1 - 3.5e-13 49.7 0.0 7.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ13634.1 - 4.4e-11 43.1 0.3 6.2e-10 39.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ13634.1 - 3.8e-07 30.0 0.0 7.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ13634.1 - 0.0017 18.6 0.1 0.01 16.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 OAJ13634.1 - 0.006 17.1 4.9 0.043 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ13634.1 - 0.0088 16.4 0.2 0.049 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAJ13634.1 - 0.013 14.8 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 KaiC Pyr_redox_2 PF07992.14 OAJ13635.1 - 2e-31 109.3 0.1 2.6e-31 109.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ13635.1 - 2.7e-12 47.1 0.3 3.1e-10 40.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ13635.1 - 3.9e-12 46.0 0.0 7.9e-10 38.5 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ13635.1 - 2.7e-07 30.5 5.0 0.053 13.1 0.2 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ13635.1 - 1.6e-06 27.5 0.6 0.00024 20.4 0.1 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 OAJ13635.1 - 1.7e-05 23.9 0.1 0.00024 20.1 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase TrkA_N PF02254.18 OAJ13635.1 - 2.1e-05 24.7 0.4 0.34 11.2 0.0 3.0 3 1 0 3 3 2 2 TrkA-N domain NAD_binding_7 PF13241.6 OAJ13635.1 - 0.00027 21.4 0.1 0.12 12.8 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 OAJ13635.1 - 0.0041 16.4 0.3 1.9 7.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 OAJ13635.1 - 0.0085 16.1 0.8 13 5.8 0.1 3.9 2 2 2 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ13635.1 - 0.01 16.1 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ13635.1 - 0.011 15.0 0.2 0.052 12.8 0.1 1.9 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAJ13635.1 - 0.042 12.5 1.0 2.8 6.5 0.1 3.2 2 1 2 4 4 4 0 HI0933-like protein GFO_IDH_MocA PF01408.22 OAJ13635.1 - 0.097 13.5 0.4 5.7 7.8 0.0 3.1 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold GTP_cyclohydroI PF01227.22 OAJ13636.1 - 3e-75 251.6 0.4 7.1e-75 250.4 0.1 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.6 OAJ13636.1 - 0.002 18.2 0.0 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 OAJ13636.1 - 0.04 13.9 0.1 0.083 12.9 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Hamartin PF04388.12 OAJ13636.1 - 2.5 6.6 8.1 3.4 6.2 8.1 1.2 1 0 0 1 1 1 0 Hamartin protein BolA PF01722.18 OAJ13637.1 - 3e-12 46.7 0.0 8.2e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein GATase_6 PF13522.6 OAJ13638.1 - 3.1e-15 56.6 0.0 7.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ13638.1 - 7.6e-11 42.0 0.0 1.6e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAJ13638.1 - 2.3e-09 37.0 0.2 4e-09 36.2 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAJ13638.1 - 9e-06 24.8 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Abhydrolase_1 PF00561.20 OAJ13639.1 - 3.6e-18 66.1 0.8 1.5e-14 54.3 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ13639.1 - 4.9e-12 45.6 0.0 6.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ13639.1 - 9e-10 39.5 2.0 9e-10 39.5 2.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 OAJ13639.1 - 0.00027 20.7 0.0 0.00096 18.9 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 OAJ13639.1 - 0.005 15.6 0.0 0.0066 15.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 OAJ13639.1 - 0.062 13.1 0.0 1.4 8.7 0.0 2.1 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 OAJ13639.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family NDK PF00334.19 OAJ13640.1 - 5.3e-49 165.7 0.0 7.1e-49 165.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ADH_zinc_N_2 PF13602.6 OAJ13641.1 - 0.0065 17.5 0.0 0.027 15.5 0.0 2.0 1 1 0 2 2 2 1 Zinc-binding dehydrogenase TB2_DP1_HVA22 PF03134.19 OAJ13649.1 - 1.9e-20 72.6 7.6 2.1e-20 72.5 3.7 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family zf-C3HC4_2 PF13923.6 OAJ13650.1 - 2.3e-08 33.7 14.5 3.7e-08 33.1 14.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ13650.1 - 3.8e-07 29.9 9.6 5.7e-07 29.3 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ13650.1 - 6.5e-07 29.6 13.7 1.1e-06 28.9 13.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ13650.1 - 2.3e-05 24.2 13.4 3.9e-05 23.4 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ13650.1 - 0.00032 20.6 11.1 0.00056 19.8 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ13650.1 - 0.0023 17.8 10.7 0.0047 16.8 10.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ13650.1 - 0.0026 17.9 13.3 0.0047 17.0 13.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF3450 PF11932.8 OAJ13650.1 - 0.0044 16.3 1.0 0.0044 16.3 1.0 2.5 2 0 0 2 2 1 1 Protein of unknown function (DUF3450) XhlA PF10779.9 OAJ13650.1 - 0.0055 16.9 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Haemolysin XhlA ADIP PF11559.8 OAJ13650.1 - 0.0066 16.5 1.3 0.0066 16.5 1.3 3.0 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 OAJ13650.1 - 0.0068 16.7 2.0 0.0068 16.7 2.0 2.4 2 0 0 2 2 2 1 Csm1 N-terminal domain CLZ PF16526.5 OAJ13650.1 - 0.0068 16.7 0.7 0.016 15.6 0.7 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RasGAP_C PF03836.15 OAJ13650.1 - 0.0089 16.2 0.6 0.076 13.2 0.0 2.3 2 0 0 2 2 2 1 RasGAP C-terminus zf-RING_UBOX PF13445.6 OAJ13650.1 - 0.034 14.2 12.1 0.069 13.2 12.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Fib_alpha PF08702.10 OAJ13650.1 - 0.05 13.8 0.4 0.05 13.8 0.4 1.8 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family DUF4472 PF14739.6 OAJ13650.1 - 0.051 14.3 0.5 0.051 14.3 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) TSC22 PF01166.18 OAJ13650.1 - 0.078 13.3 0.4 0.18 12.1 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Baculo_IE-1 PF05290.11 OAJ13650.1 - 0.082 12.9 1.7 0.15 12.0 1.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ilar_coat PF01787.16 OAJ13650.1 - 0.097 12.5 0.3 0.097 12.5 0.3 2.5 2 0 0 2 2 2 0 Ilarvirus coat protein SlyX PF04102.12 OAJ13650.1 - 0.1 13.2 0.5 0.1 13.2 0.5 2.6 2 0 0 2 2 2 0 SlyX NPV_P10 PF05531.12 OAJ13650.1 - 0.14 12.7 0.1 0.14 12.7 0.1 1.7 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein zf-rbx1 PF12678.7 OAJ13650.1 - 0.27 11.5 13.1 0.98 9.8 13.1 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF812 PF05667.11 OAJ13650.1 - 0.33 9.8 15.8 0.088 11.7 7.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 OAJ13650.1 - 1.2 7.9 7.2 0.098 11.5 1.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 OAJ13650.1 - 2.3 6.0 5.8 0.23 9.3 0.6 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Taxilin PF09728.9 OAJ13650.1 - 3.5 6.7 13.6 0.023 13.9 2.7 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein zf-RING_4 PF14570.6 OAJ13650.1 - 4.3 7.2 9.6 8.3 6.3 9.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Spc24 PF08286.11 OAJ13650.1 - 6.8 7.0 6.1 0.54 10.5 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 WD40 PF00400.32 OAJ13651.1 - 1.1e-06 29.2 13.4 0.6 11.1 0.0 6.5 6 2 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 OAJ13651.1 - 0.0029 16.4 0.8 0.11 11.1 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 CHD5 PF04420.14 OAJ13653.1 - 3.4e-50 170.0 0.1 4.8e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 CHD5-like protein Snapin_Pallidin PF14712.6 OAJ13653.1 - 0.074 13.5 0.7 0.13 12.7 0.7 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Pro_isomerase PF00160.21 OAJ13655.1 - 1.9e-46 158.2 0.0 2.7e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAJ13655.1 - 2.5e-05 24.0 5.9 0.0084 16.2 0.8 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13655.1 - 0.00052 20.0 0.7 0.0021 18.1 0.7 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ13655.1 - 0.0006 19.5 3.2 0.012 15.4 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ZapD PF07072.11 OAJ13655.1 - 0.038 13.8 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Cell division protein TPR_6 PF13174.6 OAJ13655.1 - 0.13 12.9 3.1 2.3 9.1 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ13655.1 - 0.16 12.2 1.2 2 8.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat COG4 PF08318.12 OAJ13656.1 - 1.1e-68 231.8 0.0 1.2e-67 228.4 0.0 2.5 2 1 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 OAJ13656.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family UTP15_C PF09384.10 OAJ13656.1 - 0.15 11.7 0.4 0.55 9.9 0.2 2.0 2 0 0 2 2 2 0 UTP15 C terminal COG2 PF06148.11 OAJ13656.1 - 0.85 9.7 3.1 1.2 9.2 1.2 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PIRT PF15099.6 OAJ13657.1 - 0.00062 19.3 0.2 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-interacting protein family Herpes_UL25 PF01499.16 OAJ13657.1 - 0.09 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Vps8 PF12816.7 OAJ13658.1 - 0.057 12.9 0.0 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 DUF1421 PF07223.11 OAJ13658.1 - 0.39 10.6 3.9 12 5.8 0.1 3.4 3 0 0 3 3 3 0 UBA-like domain (DUF1421) NOA36 PF06524.12 OAJ13659.1 - 0.34 10.2 6.8 0.44 9.8 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 OAJ13659.1 - 0.38 10.6 9.3 0.49 10.2 9.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 OAJ13659.1 - 1.4 7.1 11.6 1.5 7.1 11.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 OAJ13659.1 - 2.6 7.2 5.5 3.8 6.7 5.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.17 OAJ13659.1 - 4.7 7.3 7.7 5.4 7.1 7.7 1.1 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.14 OAJ13659.1 - 9 6.0 17.0 21 4.8 17.0 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein zinc_ribbon_15 PF17032.5 OAJ13660.1 - 6.9e-06 26.7 0.4 6.9e-06 26.7 0.4 1.5 2 0 0 2 2 2 1 zinc-ribbon family FYVE_2 PF02318.16 OAJ13660.1 - 0.0071 16.5 4.4 0.34 11.1 0.1 2.1 1 1 1 2 2 2 2 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 OAJ13660.1 - 1.1 9.3 7.6 5.7 7.0 7.6 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Ras PF00071.22 OAJ13662.1 - 5.5e-65 217.9 0.8 6.5e-65 217.7 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ13662.1 - 5.1e-36 123.5 0.1 7.9e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ13662.1 - 1.1e-17 64.0 0.1 1.4e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ13662.1 - 6.8e-06 26.1 1.0 0.073 13.0 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ13662.1 - 1.4e-05 24.7 0.3 3.4e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ13662.1 - 2.4e-05 23.8 0.1 2.7e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ13662.1 - 5.2e-05 23.3 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ13662.1 - 6.1e-05 22.5 0.1 7.8e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAJ13662.1 - 0.0046 16.5 0.0 0.036 13.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OAJ13662.1 - 0.0088 16.4 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAJ13662.1 - 0.017 15.5 0.1 0.94 9.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAJ13662.1 - 0.041 13.6 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIRC PF00731.20 OAJ13662.1 - 0.049 13.2 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 AIR carboxylase AAA_5 PF07728.14 OAJ13662.1 - 0.051 13.6 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ13662.1 - 0.055 13.7 0.0 0.088 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ13662.1 - 0.065 12.7 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 OAJ13662.1 - 0.069 12.6 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein PduV-EutP PF10662.9 OAJ13662.1 - 0.092 12.5 0.0 1.6 8.5 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 OAJ13662.1 - 0.17 11.5 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MUG113 PF13455.6 OAJ13670.1 - 1.1e-11 45.2 0.0 2.6e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 OAJ13670.1 - 5.1e-10 39.8 0.0 1.9e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 T5orf172 domain PNK3P PF08645.11 OAJ13671.1 - 7e-38 129.9 1.2 1.2e-21 77.1 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAJ13671.1 - 6.4e-20 71.8 0.1 1.4e-08 35.0 0.2 3.3 2 1 1 3 3 3 2 AAA domain PGP_phosphatase PF09419.10 OAJ13671.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Aldo_ket_red PF00248.21 OAJ13672.1 - 3.6e-44 151.1 0.0 9.1e-34 117.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family CBFD_NFYB_HMF PF00808.23 OAJ13673.1 - 1.6e-15 57.1 0.3 3e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ13673.1 - 1.3e-12 48.2 0.4 2.3e-12 47.4 0.4 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 OAJ13673.1 - 0.75 9.5 5.4 0.11 12.3 0.9 1.8 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family BUD22 PF09073.10 OAJ13675.1 - 0.1 11.9 22.4 0.11 11.8 22.4 1.0 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 OAJ13675.1 - 1.3 8.4 16.9 1.5 8.1 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.12 OAJ13675.1 - 2.4 6.0 7.2 2.8 5.8 7.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_Ag35 PF03286.14 OAJ13675.1 - 2.5 7.9 20.0 0.75 9.6 13.0 2.0 1 1 1 2 2 2 0 Pox virus Ag35 surface protein DUF2722 PF10846.8 OAJ13675.1 - 3.5 6.4 10.1 3.9 6.3 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Myc_N PF01056.18 OAJ13675.1 - 4.1 7.2 17.2 0.44 10.4 10.7 1.9 1 1 1 2 2 2 0 Myc amino-terminal region NOA36 PF06524.12 OAJ13675.1 - 5.5 6.2 29.4 0.68 9.2 20.2 2.0 2 0 0 2 2 2 0 NOA36 protein Kelch_4 PF13418.6 OAJ13676.1 - 3.7e-29 100.5 15.7 3.4e-08 33.4 0.1 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ13676.1 - 2.8e-28 97.6 18.6 1.6e-08 34.6 0.3 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ13676.1 - 4.7e-24 83.9 8.2 3.2e-06 27.0 0.0 5.8 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 OAJ13676.1 - 3.3e-21 75.1 0.6 3.3e-21 75.1 0.6 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 OAJ13676.1 - 1.3e-20 72.9 13.1 3.1e-06 27.2 0.2 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAJ13676.1 - 4.6e-14 51.7 12.1 2e-06 27.3 0.1 5.9 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 OAJ13676.1 - 9.9e-10 38.0 3.7 0.0039 17.1 0.1 5.5 5 1 0 5 5 5 2 Kelch motif SET PF00856.28 OAJ13676.1 - 2.2 8.6 10.0 33 4.8 0.2 3.3 3 0 0 3 3 3 0 SET domain Condensation PF00668.20 OAJ13677.1 - 0.00042 19.1 0.0 0.0033 16.2 0.0 2.3 2 1 0 2 2 2 1 Condensation domain AMP-binding PF00501.28 OAJ13677.1 - 0.0066 15.1 0.2 0.011 14.3 0.2 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ABC_tran PF00005.27 OAJ13678.1 - 7.8e-45 152.8 0.0 9.1e-27 94.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ13678.1 - 5e-39 134.6 15.2 1.9e-20 73.7 5.6 3.5 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ13678.1 - 3.3e-11 43.0 0.5 0.00012 21.7 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ13678.1 - 1.8e-07 30.8 0.3 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ13678.1 - 7.2e-06 26.6 0.2 0.046 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ13678.1 - 1.1e-05 25.7 0.3 0.046 14.0 0.3 3.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ13678.1 - 6.5e-05 23.4 0.4 0.33 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ13678.1 - 0.0001 22.3 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAJ13678.1 - 0.00011 22.1 0.2 0.95 9.2 0.0 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ13678.1 - 0.00035 20.6 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 OAJ13678.1 - 0.00052 19.2 0.1 0.18 10.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 OAJ13678.1 - 0.00077 19.6 0.3 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 OAJ13678.1 - 0.0027 17.8 2.0 0.014 15.5 0.1 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain SbcCD_C PF13558.6 OAJ13678.1 - 0.003 17.8 0.5 0.46 10.8 0.1 3.9 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 OAJ13678.1 - 0.0035 16.7 0.4 0.077 12.3 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 OAJ13678.1 - 0.0099 14.7 0.7 0.035 12.9 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_30 PF13604.6 OAJ13678.1 - 0.023 14.4 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 OAJ13678.1 - 0.026 13.5 0.1 0.048 12.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 OAJ13678.1 - 0.028 14.1 0.1 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 OAJ13678.1 - 0.04 13.5 0.7 9.4 5.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAJ13678.1 - 0.086 13.0 0.0 24 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 OAJ13678.1 - 0.12 11.1 0.8 5.5 5.7 0.1 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Cytochrom_B_C PF00032.17 OAJ13679.1 - 0.35 11.2 5.0 1.6 9.1 0.3 3.0 3 0 0 3 3 3 0 Cytochrome b(C-terminal)/b6/petD Gpr1_Fun34_YaaH PF01184.19 OAJ13680.1 - 1e-27 97.1 16.4 1.4e-27 96.7 16.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SSP160 PF06933.11 OAJ13689.1 - 8.3 4.5 19.5 0.19 9.9 7.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Mito_carr PF00153.27 OAJ13690.1 - 4.7e-36 122.6 5.4 2.7e-13 49.6 0.1 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.18 OAJ13691.1 - 4.1e-14 52.2 0.7 8.9e-14 51.1 0.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ13691.1 - 7.7e-05 22.7 7.5 0.00014 21.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.12 OAJ13691.1 - 0.029 13.8 7.2 0.045 13.2 7.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ13691.1 - 0.034 12.5 8.7 0.046 12.0 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ13691.1 - 0.036 14.2 14.0 0.013 15.6 10.6 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Mpp10 PF04006.12 OAJ13691.1 - 0.056 11.9 6.4 0.082 11.3 6.4 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 OAJ13691.1 - 0.071 11.7 13.9 0.16 10.6 13.9 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IFT57 PF10498.9 OAJ13691.1 - 1.8 7.4 6.6 22 3.9 0.0 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 PGA2 PF07543.12 OAJ13691.1 - 1.9 8.5 7.0 5.2 7.1 7.0 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 RXT2_N PF08595.11 OAJ13691.1 - 3.1 7.8 6.2 7.2 6.6 6.2 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 OAJ13691.1 - 6.5 6.4 13.5 13 5.4 13.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDP-OH_P_transf PF01066.21 OAJ13692.1 - 2.6e-12 47.3 0.7 2.6e-12 47.3 0.7 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Flavodoxin_NdrI PF07972.11 OAJ13692.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like K_trans PF02705.16 OAJ13693.1 - 1.1e-153 512.7 7.7 1.3e-153 512.4 7.7 1.1 1 0 0 1 1 1 1 K+ potassium transporter DUF5526 PF17664.1 OAJ13693.1 - 0.013 15.1 2.5 2.2 7.8 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5526) Aldo_ket_red PF00248.21 OAJ13694.1 - 1.7e-49 168.6 0.0 1.9e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_1 PF00561.20 OAJ13696.1 - 0.0014 18.4 0.2 0.005 16.5 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold GRIM-19 PF06212.12 OAJ13697.1 - 5.1e-32 110.6 0.0 5.9e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein ATP-synt_C PF00137.21 OAJ13710.1 - 4.7e-28 97.3 33.6 8e-16 58.1 12.3 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Ras PF00071.22 OAJ13711.1 - 1.3e-45 154.9 0.0 1.6e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ13711.1 - 3.8e-15 56.2 0.0 5.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ13711.1 - 2.6e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ13711.1 - 3.8e-05 23.6 0.0 0.0078 16.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ13711.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAJ13711.1 - 0.033 14.6 0.0 0.043 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ13711.1 - 0.052 13.6 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 OAJ13711.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 OAJ13711.1 - 0.067 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 OAJ13711.1 - 0.15 12.1 0.1 0.47 10.5 0.0 1.7 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain NUDIX_2 PF13869.6 OAJ13712.1 - 5.7e-79 264.1 0.0 6.5e-79 263.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Mito_carr PF00153.27 OAJ13713.1 - 9.1e-64 211.4 1.4 1.9e-21 75.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1242 PF06842.12 OAJ13714.1 - 1.2e-18 66.6 1.4 1.6e-18 66.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.6 OAJ13714.1 - 0.23 11.8 0.4 0.35 11.3 0.4 1.3 1 0 0 1 1 1 0 Jag N-terminus UAA PF08449.11 OAJ13715.1 - 4.1e-76 256.1 4.2 3.5e-59 200.5 0.0 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 OAJ13715.1 - 0.00056 19.2 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 OAJ13715.1 - 0.01 14.9 0.1 0.01 14.9 0.1 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Exo_endo_phos PF03372.23 OAJ13716.1 - 6.8e-06 25.8 0.0 3e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4078 PF13300.6 OAJ13717.1 - 3e-16 59.5 1.0 3e-16 59.5 1.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) Brix PF04427.18 OAJ13718.1 - 6.2e-37 127.6 0.1 8.7e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Brix domain YL1 PF05764.13 OAJ13718.1 - 0.0016 18.6 20.6 0.012 15.7 9.4 2.3 2 0 0 2 2 2 2 YL1 nuclear protein BSP_II PF05432.11 OAJ13718.1 - 0.019 14.6 9.1 0.42 10.3 2.8 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CAC1F_C PF16885.5 OAJ13718.1 - 0.13 11.9 4.4 0.76 9.4 0.7 2.2 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term CDC45 PF02724.14 OAJ13718.1 - 0.82 7.9 17.2 0.22 9.8 7.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Sporozoite_P67 PF05642.11 OAJ13718.1 - 1.1 7.2 7.6 3.1 5.8 0.8 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 OAJ13718.1 - 1.2 9.0 17.6 1.6 8.5 7.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_Rpc4 PF05132.14 OAJ13718.1 - 1.6 9.2 8.0 0.43 11.0 0.5 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Merozoite_SPAM PF07133.11 OAJ13718.1 - 2.5 8.0 25.3 0.65 10.0 3.7 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF913 PF06025.12 OAJ13718.1 - 6 5.7 7.3 8.1 5.3 0.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Inhibitor_I9 PF05922.16 OAJ13719.1 - 1.1e-05 26.0 0.1 5.6e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 OAJ13719.1 - 0.054 13.3 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain COX7C PF02935.16 OAJ13720.1 - 1.9e-08 34.4 3.7 1.9e-08 34.4 3.7 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc DC_STAMP PF07782.13 OAJ13720.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 DC-STAMP-like protein Snf7 PF03357.21 OAJ13721.1 - 1.5e-32 112.6 12.0 2.3e-32 112.0 12.0 1.3 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.6 OAJ13721.1 - 0.1 12.5 2.3 0.37 10.7 2.3 1.9 1 0 0 1 1 1 0 TIP39 peptide Bac_GDH PF05088.12 OAJ13721.1 - 0.11 9.9 7.4 0.12 9.9 7.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DHFR_1 PF00186.19 OAJ13722.1 - 2.2e-24 86.0 0.0 8e-22 77.6 0.0 2.8 2 1 0 2 2 2 2 Dihydrofolate reductase Mre11_DNA_bind PF04152.14 OAJ13723.1 - 1.1e-41 142.9 3.3 1.1e-41 142.9 3.3 2.2 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAJ13723.1 - 3e-12 47.5 0.1 5.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ13723.1 - 7.5e-06 26.2 0.2 0.00015 22.0 0.2 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acyl-CoA_dh_1 PF00441.24 OAJ13724.1 - 5.6e-44 150.0 2.2 8.7e-44 149.4 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ13724.1 - 5.6e-35 120.4 0.0 1.1e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ13724.1 - 9.7e-27 93.0 0.0 1.8e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ13724.1 - 5.3e-17 62.3 0.4 8.2e-17 61.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 OAJ13725.1 - 1e-72 244.0 0.0 2.4e-72 242.9 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 OAJ13725.1 - 1.3e-35 121.8 0.0 2.4e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 OAJ13725.1 - 1.3e-26 93.3 0.5 6.5e-26 91.0 0.1 2.4 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 OAJ13725.1 - 7.5e-14 51.3 3.1 2.2e-13 49.8 3.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAJ13725.1 - 2.8e-07 30.3 0.0 1.4e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAJ13725.1 - 2.1e-06 27.5 0.3 6.4e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 OAJ13725.1 - 5.2e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ13725.1 - 0.0015 19.2 5.9 0.23 12.2 0.1 3.1 3 0 0 3 3 3 2 HlyD family secretion protein DUF2118 PF09891.9 OAJ13725.1 - 0.095 12.7 0.6 0.19 11.7 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.14 OAJ13725.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HlyD_D23 PF16576.5 OAJ13725.1 - 0.33 10.1 1.9 9.8 5.3 0.3 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion AMPK1_CBM PF16561.5 OAJ13726.1 - 1.4e-12 47.6 0.6 2.6e-12 46.8 0.6 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SseC PF04888.12 OAJ13726.1 - 0.0014 18.3 10.2 0.0014 18.3 10.2 3.7 3 1 0 3 3 3 1 Secretion system effector C (SseC) like family DUF4199 PF13858.6 OAJ13726.1 - 0.042 14.2 5.2 17 5.8 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Trep_Strep PF09605.10 OAJ13726.1 - 0.31 11.0 2.1 14 5.6 0.1 2.8 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1772 PF08592.11 OAJ13726.1 - 3.4 8.0 0.0 3.4 8.0 0.0 4.5 2 2 1 5 5 5 0 Domain of unknown function (DUF1772) Spc7 PF08317.11 OAJ13727.1 - 1.6e-19 70.0 3.9 3.1e-19 69.0 3.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 OAJ13727.1 - 3.2e-06 27.1 0.1 6.6e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 BSP_II PF05432.11 OAJ13727.1 - 0.017 14.8 16.2 0.13 11.9 6.5 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Wbp11 PF09429.10 OAJ13727.1 - 0.074 13.5 2.3 0.2 12.1 2.3 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 PTPRCAP PF15713.5 OAJ13727.1 - 0.54 10.5 22.7 0.49 10.7 5.3 3.1 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated FlgN PF05130.12 OAJ13727.1 - 1.1 9.8 6.0 2.5 8.6 6.0 1.6 1 1 0 1 1 1 0 FlgN protein DUF3584 PF12128.8 OAJ13727.1 - 1.1 6.7 12.7 1.6 6.1 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF148 PF02520.17 OAJ13727.1 - 1.3 9.2 4.5 0.91 9.7 1.1 2.2 1 1 0 2 2 2 0 Domain of unknown function DUF148 MPP6 PF10175.9 OAJ13727.1 - 2 8.9 12.0 1.3 9.5 0.7 2.9 3 0 0 3 3 3 0 M-phase phosphoprotein 6 DUF4407 PF14362.6 OAJ13727.1 - 3.3 7.0 6.0 5.7 6.2 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glyco_transf_90 PF05686.12 OAJ13739.1 - 4e-23 82.0 5.7 2.2e-20 72.9 4.4 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 DNA_pol_B_thumb PF14791.6 OAJ13740.1 - 2.6e-20 72.3 0.1 6.5e-20 71.1 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 OAJ13740.1 - 2.2e-19 69.8 0.0 5e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 OAJ13740.1 - 1.2e-07 31.5 0.0 4.7e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAJ13740.1 - 9e-06 26.0 0.1 2.5e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAJ13740.1 - 0.00029 21.2 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAJ13740.1 - 0.042 14.5 0.0 0.83 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Aconitase PF00330.20 OAJ13741.1 - 1.8e-148 495.4 0.0 2.5e-148 494.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ13741.1 - 1.7e-31 109.3 0.0 3.7e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.9 OAJ13741.1 - 0.0084 16.3 0.9 0.064 13.4 1.3 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 WIYLD PF10440.9 OAJ13741.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain OsmC PF02566.19 OAJ13741.1 - 0.13 12.7 1.5 2.3 8.7 0.1 3.0 3 0 0 3 3 3 0 OsmC-like protein GalKase_gal_bdg PF10509.9 OAJ13742.1 - 7.6e-21 73.4 0.1 1.6e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAJ13742.1 - 8.3e-14 51.6 4.7 1e-13 51.3 1.3 2.8 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ13742.1 - 1.7e-11 44.3 0.0 4.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GCIP PF13324.6 OAJ13743.1 - 4.8e-06 26.4 5.9 1.4e-05 24.8 0.6 2.9 2 1 1 3 3 3 2 Grap2 and cyclin-D-interacting Tim54 PF11711.8 OAJ13743.1 - 0.067 12.0 1.2 0.12 11.1 1.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Glyco_transf_90 PF05686.12 OAJ13744.1 - 2.2e-25 89.4 6.9 1.2e-22 80.4 6.3 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Lactamase_B_3 PF13483.6 OAJ13745.1 - 0.0094 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 OAJ13745.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ChaC PF04752.12 OAJ13746.1 - 1.7e-50 171.5 0.0 3.8e-50 170.4 0.0 1.6 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.31 OAJ13746.1 - 2.3e-26 91.7 1.2 5.4e-26 90.5 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAJ13746.1 - 9.5e-09 35.3 0.6 2.4e-08 34.1 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ13746.1 - 4.5e-06 26.9 0.5 8e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ13746.1 - 0.0024 18.2 0.1 0.0069 16.7 0.1 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 OAJ13746.1 - 0.7 10.5 1.7 0.87 10.2 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pyrophosphatase PF00719.19 OAJ13747.1 - 5.7e-60 201.7 0.2 7.2e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase peroxidase PF00141.23 OAJ13748.1 - 8.3e-48 163.1 0.0 1.2e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase GalKase_gal_bdg PF10509.9 OAJ13748.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.8 1 0 0 1 1 1 0 Galactokinase galactose-binding signature PPTA PF01239.22 OAJ13750.1 - 1.7e-42 141.9 17.5 5e-09 35.6 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DASH_Ask1 PF08655.10 OAJ13750.1 - 0.04 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 V-SNARE_C PF12352.8 OAJ13751.1 - 2.3e-17 63.0 7.3 4e-17 62.3 6.3 2.0 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OAJ13751.1 - 3.7e-15 56.1 2.0 3.7e-15 56.1 2.0 2.9 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus PNK3P PF08645.11 OAJ13751.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase GEMIN8 PF15348.6 OAJ13751.1 - 0.014 15.7 1.6 0.025 14.9 1.6 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Prominin PF05478.11 OAJ13751.1 - 0.029 12.4 0.1 0.029 12.4 0.1 1.8 2 0 0 2 2 2 0 Prominin Sec20 PF03908.13 OAJ13751.1 - 0.089 12.7 2.0 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Sec20 DUF4407 PF14362.6 OAJ13751.1 - 0.24 10.7 10.6 5.7 6.2 10.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Duo1 PF08651.10 OAJ13751.1 - 0.26 11.1 3.3 0.84 9.5 0.1 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 Malate_DH PF12434.8 OAJ13751.1 - 0.31 11.1 2.5 0.4 10.7 0.3 2.3 2 0 0 2 2 2 0 Malate dehydrogenase enzyme Fib_alpha PF08702.10 OAJ13751.1 - 0.41 10.8 4.7 1.9 8.7 1.5 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Sigma_reg_N PF13800.6 OAJ13751.1 - 0.82 10.0 3.4 1.4 9.2 3.4 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF3391 PF11871.8 OAJ13751.1 - 3.5 8.2 8.1 8.6 6.9 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) YqjK PF13997.6 OAJ13751.1 - 6.2 7.1 6.0 0.77 10.0 0.4 2.4 3 0 0 3 3 3 0 YqjK-like protein K_channel_TID PF07941.11 OAJ13752.1 - 0.027 14.9 0.3 0.027 14.9 0.3 3.7 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain UreE_C PF05194.12 OAJ13752.1 - 0.045 14.2 11.2 0.11 13.1 11.2 1.6 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain Ribosomal_S9 PF00380.19 OAJ13752.1 - 0.14 12.7 0.6 0.24 11.9 0.6 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Kei1 PF08552.11 OAJ13752.1 - 0.64 9.9 6.7 0.34 10.7 1.3 2.8 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Apt1 PF10351.9 OAJ13752.1 - 2.8 6.7 8.6 4.4 6.1 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2315 PF10231.9 OAJ13760.1 - 2.5e-19 69.6 0.6 2.4e-13 50.2 0.1 2.2 2 0 0 2 2 2 2 Apoptogenic protein 1 PX PF00787.24 OAJ13762.1 - 5.8e-21 74.6 0.0 1.3e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAJ13762.1 - 0.00016 21.3 2.1 0.042 13.4 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.11 OAJ13762.1 - 0.0068 15.9 0.6 0.012 15.1 0.6 1.3 1 0 0 1 1 1 1 FAM92 protein IKBKB_SDD PF18397.1 OAJ13762.1 - 0.036 13.4 0.2 0.07 12.4 0.2 1.4 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain Glyco_tranf_2_3 PF13641.6 OAJ13764.1 - 1.5e-29 103.5 0.0 2.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ13764.1 - 1.8e-09 37.7 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAJ13764.1 - 2.2e-09 37.0 0.1 2.1e-08 33.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OAJ13764.1 - 0.0011 18.9 4.1 0.0022 17.9 4.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Acyl-CoA_dh_1 PF00441.24 OAJ13768.1 - 9.6e-46 155.7 4.6 1.2e-45 155.3 4.6 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ13768.1 - 1.2e-23 83.1 0.0 2.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ13768.1 - 1.3e-21 77.2 2.4 1.7e-21 76.9 2.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Elong_Iki1 PF10483.9 OAJ13769.1 - 8.8e-15 55.0 0.0 1e-06 28.5 0.1 2.9 2 1 0 2 2 2 2 Elongator subunit Iki1 DUF1115 PF06544.12 OAJ13770.1 - 3.2e-06 27.3 0.0 4.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) HsbA PF12296.8 OAJ13771.1 - 5.1e-15 56.0 12.5 7e-15 55.5 12.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A NUDE_C PF04880.13 OAJ13771.1 - 0.26 11.7 1.5 0.42 11.1 1.5 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region RasGAP PF00616.19 OAJ13772.1 - 4e-17 62.6 0.0 2.5e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 OAJ13772.1 - 2.8e-07 30.7 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain AAA_2 PF07724.14 OAJ13773.1 - 3e-43 147.9 0.0 2.1e-39 135.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ13773.1 - 1.4e-28 98.8 0.7 1.4e-28 98.8 0.7 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAJ13773.1 - 1e-25 89.5 0.5 5.4e-25 87.3 0.0 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAJ13773.1 - 1.8e-18 67.2 0.0 3.1e-09 37.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ13773.1 - 1.3e-12 47.8 0.2 7.4e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ13773.1 - 6.7e-11 42.3 0.0 3.1e-06 27.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ13773.1 - 5.7e-10 39.8 3.3 0.00037 20.9 0.1 4.5 2 2 1 3 3 3 2 AAA ATPase domain TniB PF05621.11 OAJ13773.1 - 4.6e-06 26.2 0.3 0.0012 18.3 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 OAJ13773.1 - 2.2e-05 24.0 0.1 0.12 11.9 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 OAJ13773.1 - 5.1e-05 22.6 0.0 0.02 14.2 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 OAJ13773.1 - 6.2e-05 23.0 0.2 0.17 11.8 0.1 3.2 2 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAJ13773.1 - 8.1e-05 22.4 0.0 0.28 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAJ13773.1 - 0.00015 21.2 0.2 0.14 11.5 0.1 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAJ13773.1 - 0.0002 21.4 0.1 0.01 15.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 OAJ13773.1 - 0.00029 20.1 0.6 0.017 14.4 0.0 2.7 3 0 0 3 3 2 1 TIP49 P-loop domain AAA_22 PF13401.6 OAJ13773.1 - 0.0003 21.1 7.6 0.16 12.2 0.1 5.2 5 2 0 5 5 4 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ13773.1 - 0.00036 19.6 0.0 0.2 10.5 0.0 2.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 OAJ13773.1 - 0.00045 20.2 0.2 0.94 9.4 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 OAJ13773.1 - 0.00069 20.2 0.0 1.1 9.8 0.0 3.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 OAJ13773.1 - 0.0014 19.0 0.4 1.9 8.9 0.0 3.3 4 0 0 4 4 3 1 RNA helicase DUF853 PF05872.12 OAJ13773.1 - 0.0015 17.2 0.0 0.4 9.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) IstB_IS21 PF01695.17 OAJ13773.1 - 0.0017 18.1 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 OAJ13773.1 - 0.0025 18.2 0.2 2.2 8.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 OAJ13773.1 - 0.003 17.6 0.1 3.8 7.5 0.0 3.5 3 1 0 4 4 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 OAJ13773.1 - 0.0034 17.0 0.2 3 7.4 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_6 PF12774.7 OAJ13773.1 - 0.005 15.8 0.0 0.03 13.3 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 OAJ13773.1 - 0.0075 16.3 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CENP-F_leu_zip PF10473.9 OAJ13773.1 - 0.0096 16.0 10.2 0.023 14.7 10.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_24 PF13479.6 OAJ13773.1 - 0.011 15.5 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ13773.1 - 0.012 15.8 3.0 6.4 6.9 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA_3 PF07726.11 OAJ13773.1 - 0.013 15.4 0.0 0.29 11.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAJ13773.1 - 0.018 15.3 6.1 3.8 7.7 0.0 4.1 3 1 1 4 4 4 0 AAA domain DUF815 PF05673.13 OAJ13773.1 - 0.02 14.1 0.4 6.2 5.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) T3SS_needle_E PF08988.10 OAJ13773.1 - 0.023 14.8 0.9 0.42 10.8 0.4 3.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle RsgA_GTPase PF03193.16 OAJ13773.1 - 0.036 14.0 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Torsin PF06309.11 OAJ13773.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 1 0 Torsin PRK PF00485.18 OAJ13773.1 - 0.057 13.2 0.1 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UvrD-helicase PF00580.21 OAJ13773.1 - 0.23 11.0 0.1 0.23 11.0 0.1 3.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.17 OAJ13773.1 - 5 7.2 6.3 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain DUF1318 PF07027.12 OAJ13782.1 - 0.0064 16.9 0.2 0.0081 16.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1318) Rieske_2 PF13806.6 OAJ13791.1 - 0.051 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Sulf_transp PF04143.14 OAJ13793.1 - 0.00012 21.7 27.7 0.015 14.9 1.7 4.2 2 1 2 4 4 4 3 Sulphur transport Pkinase PF00069.25 OAJ13794.1 - 2e-67 227.4 0.0 3.3e-67 226.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13794.1 - 4.5e-50 170.3 0.0 7.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ13794.1 - 2.6e-05 23.2 2.2 0.00013 20.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ13794.1 - 0.031 13.2 0.0 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 OAJ13794.1 - 0.079 12.3 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like TFIIA PF03153.13 OAJ13794.1 - 0.14 12.1 16.5 0.22 11.5 16.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 OAJ13794.1 - 0.89 8.5 11.2 1.2 8.1 11.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SOG2 PF10428.9 OAJ13794.1 - 2.9 7.0 15.1 3.8 6.6 15.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Caleosin PF05042.13 OAJ13795.1 - 1e-63 214.3 0.1 1.3e-63 214.0 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein DUF3384 PF11864.8 OAJ13796.1 - 1e-60 206.1 0.0 1.4e-59 202.3 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OAJ13796.1 - 5.3e-43 146.7 0.0 9.7e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAJ13796.1 - 4.9e-32 111.4 4.8 3e-29 102.2 5.0 3.0 2 1 0 2 2 2 2 Tuberin Glycogen_syn PF05693.13 OAJ13797.1 - 0 1131.8 0.0 0 1131.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAJ13797.1 - 1.4e-07 31.3 0.0 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAJ13797.1 - 9.4e-07 28.8 0.0 3.2e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 OAJ13797.1 - 3e-06 27.7 0.0 0.0044 17.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ13797.1 - 0.00016 22.1 0.0 0.00036 21.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 OAJ13797.1 - 0.00027 21.0 0.4 0.00054 20.0 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DUF1978 PF09321.10 OAJ13797.1 - 2.5 7.4 5.0 1.1 8.6 1.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1978) PTPA PF03095.15 OAJ13808.1 - 5.6e-90 301.8 0.0 6.8e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein tRNA-synt_2b PF00587.25 OAJ13811.1 - 2.8e-32 112.2 0.0 5.1e-29 101.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ13811.1 - 3e-17 62.6 0.3 6.6e-17 61.5 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 OAJ13811.1 - 4.9e-13 48.9 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 OAJ13811.1 - 1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.13 OAJ13811.1 - 0.033 14.1 0.0 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF502) Acetyltransf_4 PF13420.7 OAJ13811.1 - 0.091 12.9 0.1 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HOIP-UBA PF16678.5 OAJ13811.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair SICA_alpha PF12887.7 OAJ13811.1 - 0.15 11.9 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 SICA extracellular alpha domain HAP1_N PF04849.13 OAJ13812.1 - 0.0088 15.3 0.2 0.0088 15.3 0.2 3.3 3 0 0 3 3 3 2 HAP1 N-terminal conserved region Abhydrolase_2 PF02230.16 OAJ13813.1 - 4.3e-05 23.4 0.0 6.6e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase RhoGEF PF00621.20 OAJ13814.1 - 2.8e-12 47.3 0.0 4.9e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain POTRA_TamA_1 PF17243.2 OAJ13815.1 - 0.036 14.1 0.2 12 6.1 0.0 3.1 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DUF4043 PF13252.6 OAJ13815.1 - 0.12 11.4 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) Abhydro_lipase PF04083.16 OAJ13815.1 - 0.16 11.5 0.0 0.78 9.4 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region zf-LYAR PF08790.11 OAJ13816.1 - 1.1e-11 44.4 1.3 1.1e-11 44.4 1.3 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Ferritin_2 PF13668.6 OAJ13817.1 - 5.7e-07 29.8 0.0 8e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Shisa PF13908.6 OAJ13818.1 - 0.22 11.7 3.3 6.7 6.9 0.1 3.3 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 OAJ13818.1 - 1.2 10.1 4.1 7.4 7.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4834 PF16118.5 OAJ13819.1 - 0.2 12.6 3.5 3.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 OAJ13831.1 - 1.2e-36 126.4 0.0 2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13831.1 - 1.1e-25 90.4 0.0 1.7e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ13831.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family B-block_TFIIIC PF04182.12 OAJ13832.1 - 2.5e-08 33.9 0.0 7.1e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 OAJ13832.1 - 0.044 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain PNGaseA PF12222.8 OAJ13833.1 - 9.1e-89 298.3 1.1 2.2e-88 297.0 1.1 1.6 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A EMC1_C PF07774.13 OAJ13834.1 - 1e-62 211.6 0.0 1.5e-62 211.0 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAJ13834.1 - 4.5e-09 36.2 9.2 0.00026 20.7 0.3 4.3 3 1 1 4 4 4 4 PQQ-like domain PQQ PF01011.21 OAJ13834.1 - 0.0067 16.3 5.6 30 4.8 0.0 5.2 5 1 0 5 5 5 3 PQQ enzyme repeat UIM PF02809.20 OAJ13835.1 - 0.0051 16.6 0.9 0.0051 16.6 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin interaction motif adh_short_C2 PF13561.6 OAJ13837.1 - 8.3e-39 133.5 0.4 1.2e-24 87.2 0.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ13837.1 - 8.8e-32 110.1 1.0 1.2e-31 109.7 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ13837.1 - 4.1e-17 62.7 0.2 7.5e-17 61.8 0.2 1.5 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAJ13837.1 - 0.00099 18.6 0.0 0.0016 17.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ13837.1 - 0.001 18.6 0.2 0.0019 17.7 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CoA_binding PF02629.19 OAJ13837.1 - 0.041 14.6 0.7 2.6 8.8 0.0 2.6 2 1 0 2 2 2 0 CoA binding domain 3HCDH_N PF02737.18 OAJ13837.1 - 0.062 13.2 1.4 0.18 11.7 1.4 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PS_Dcarbxylase PF02666.15 OAJ13838.1 - 1.9e-41 141.8 0.0 2.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF348 PF03990.14 OAJ13838.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain IML1 PF12257.8 OAJ13847.1 - 2.1e-112 374.9 0.0 3.1e-112 374.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 OAJ13847.1 - 9.9e-18 64.0 0.2 1.3e-16 60.4 0.1 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) rve_3 PF13683.6 OAJ13847.1 - 0.24 11.2 7.1 6 6.7 0.0 3.5 3 0 0 3 3 3 0 Integrase core domain HLH PF00010.26 OAJ13848.1 - 3.4e-16 58.9 0.1 7.9e-16 57.8 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pro-kuma_activ PF09286.11 OAJ13849.1 - 3.6e-21 76.0 0.1 6.3e-21 75.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ13849.1 - 1.8e-10 40.6 4.9 1.8e-10 40.6 4.9 1.9 1 1 1 2 2 2 1 Subtilase family Hydrolase_4 PF12146.8 OAJ13851.1 - 3e-05 23.4 0.0 0.007 15.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ13851.1 - 0.0003 21.5 2.3 0.0005 20.8 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TMEM40 PF15817.5 OAJ13851.1 - 0.0086 15.8 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Transmembrane protein 40 family Methyltransf_28 PF02636.17 OAJ13851.1 - 0.043 13.4 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lipase_3 PF01764.25 OAJ13851.1 - 0.095 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) RSN1_7TM PF02714.15 OAJ13852.1 - 9.3e-76 254.7 20.9 1.8e-75 253.8 20.9 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ13852.1 - 7e-40 137.1 0.2 1e-39 136.6 0.2 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ13852.1 - 1.3e-36 125.7 1.1 1.3e-36 125.7 1.1 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAJ13852.1 - 1.1e-07 31.9 0.0 3.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Anoctamin PF04547.12 OAJ13852.1 - 0.042 12.7 0.2 0.042 12.7 0.2 2.4 3 0 0 3 3 3 0 Calcium-activated chloride channel DUF2207 PF09972.9 OAJ13852.1 - 0.18 10.5 3.1 0.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF1365 PF07103.11 OAJ13853.1 - 1.8e-53 181.7 0.0 3e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) GST_N_3 PF13417.6 OAJ13854.1 - 0.00062 20.1 0.0 0.0025 18.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SgrR_N PF12793.7 OAJ13855.1 - 0.056 13.7 0.1 0.19 12.0 0.1 1.9 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term PAS_9 PF13426.7 OAJ13862.1 - 1.8e-24 86.0 0.0 7.7e-16 58.2 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OAJ13862.1 - 9.5e-15 54.6 0.0 2.2e-09 37.3 0.0 3.8 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 OAJ13862.1 - 1.3e-13 51.1 0.0 5.2e-08 33.1 0.0 4.4 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OAJ13862.1 - 2.1e-06 28.0 0.0 0.0017 18.5 0.0 4.5 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 OAJ13862.1 - 6.6e-06 26.0 0.0 0.0068 16.4 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 OAJ13862.1 - 0.003 17.7 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 PAS domain Lipase_3 PF01764.25 OAJ13863.1 - 4.3e-22 78.5 0.0 8.8e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Attacin_N PF03768.15 OAJ13863.1 - 9.8 6.4 7.4 0.38 10.9 0.7 2.2 2 0 0 2 2 2 0 Attacin, N-terminal region HEAT PF02985.22 OAJ13864.1 - 4.2e-21 73.2 36.7 0.88 10.0 0.1 20.3 23 0 0 23 23 21 5 HEAT repeat Lipase_3 PF01764.25 OAJ13864.1 - 2e-19 69.9 0.1 5.7e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Lipase (class 3) HEAT_EZ PF13513.6 OAJ13864.1 - 2.6e-16 59.7 47.2 7.8e-05 23.1 0.0 18.1 17 3 4 21 21 19 5 HEAT-like repeat HEAT_2 PF13646.6 OAJ13864.1 - 3.2e-13 49.9 64.8 0.0018 18.7 0.0 14.8 13 4 4 17 17 16 6 HEAT repeats CLASP_N PF12348.8 OAJ13864.1 - 4.5e-11 42.7 0.3 6.2e-06 25.9 0.1 4.8 5 0 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAJ13864.1 - 9.6e-09 35.7 0.0 0.089 13.4 0.0 6.3 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Ecm29 PF13001.7 OAJ13864.1 - 6.2e-06 25.2 1.2 0.43 9.2 0.0 4.3 3 1 0 3 3 3 2 Proteasome stabiliser Cnd3 PF12719.7 OAJ13864.1 - 0.00021 20.6 0.3 7.5 5.7 0.0 4.0 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.7 OAJ13864.1 - 0.00053 20.2 3.4 0.071 13.4 0.0 4.7 4 0 0 4 4 3 1 HEAT repeat associated with sister chromatid cohesion DRIM PF07539.12 OAJ13864.1 - 0.0021 16.4 7.1 0.0085 14.5 0.2 4.3 3 1 0 3 3 3 1 Down-regulated in metastasis DUF3437 PF11919.8 OAJ13864.1 - 0.0039 17.1 0.6 7.2 6.6 0.0 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) MMS19_C PF12460.8 OAJ13864.1 - 0.0062 15.7 6.6 8.4 5.4 0.0 6.9 8 0 0 8 8 8 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 OAJ13864.1 - 0.0096 16.1 4.7 7.8 6.7 0.0 6.3 6 1 1 7 7 6 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 OAJ13864.1 - 0.025 14.7 0.2 38 4.3 0.0 4.7 4 1 1 5 5 5 0 Parkin co-regulated protein FANCI_S2 PF14676.6 OAJ13864.1 - 0.36 11.1 1.7 72 3.6 0.2 4.2 3 1 0 3 3 3 0 FANCI solenoid 2 UNC45-central PF11701.8 OAJ13864.1 - 0.37 10.7 2.2 1.9e+02 1.9 0.2 4.5 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central VID27 PF08553.10 OAJ13866.1 - 2.8e-159 529.9 0.1 4.3e-159 529.3 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAJ13866.1 - 8.7e-39 133.1 0.0 8.7e-39 133.1 0.0 4.4 3 2 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 OAJ13866.1 - 1.5e-27 96.0 3.1 3.3e-27 94.9 3.1 1.6 1 0 0 1 1 1 1 VID27 PH-like domain MSP1_C PF07462.11 OAJ13866.1 - 0.42 9.3 5.4 0.66 8.6 5.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DNA_pol_E_B PF04042.16 OAJ13867.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B CKS PF01111.19 OAJ13868.1 - 8.9e-36 122.0 0.2 1.2e-35 121.6 0.2 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ATP-synt_10 PF05176.14 OAJ13869.1 - 1.2e-45 155.7 0.0 7e-30 104.1 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein Ndc1_Nup PF09531.10 OAJ13869.1 - 0.038 12.7 5.2 0.057 12.1 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RhoGAP PF00620.27 OAJ13882.1 - 1.5e-43 148.2 0.0 3.1e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 OAJ13882.1 - 8.5e-05 23.0 0.0 0.00063 20.2 0.0 2.3 1 1 0 1 1 1 1 PH domain PX PF00787.24 OAJ13882.1 - 0.00035 20.5 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 PX domain eIF-5a PF01287.20 OAJ13883.1 - 2.2e-29 101.3 0.8 3.1e-29 100.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 OAJ13883.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Pil1 PF13805.6 OAJ13883.1 - 0.029 13.9 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 RRM_1 PF00076.22 OAJ13884.1 - 2.2e-45 152.4 0.0 5.8e-18 64.5 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ13884.1 - 0.023 14.7 0.0 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 OAJ13884.1 - 0.042 13.9 0.0 20 5.3 0.0 3.7 3 0 0 3 3 3 0 RNA binding motif PHM7_cyt PF14703.6 OAJ13884.1 - 0.048 13.9 1.1 9.2 6.5 0.0 4.0 3 1 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter ABC2_membrane PF01061.24 OAJ13885.1 - 5.6e-64 215.4 50.7 2.6e-34 118.5 19.5 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ13885.1 - 2.6e-36 125.1 0.0 3.6e-17 63.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ13885.1 - 8.3e-21 73.7 0.0 8.3e-21 73.7 0.0 3.4 4 0 0 4 4 2 1 CDR ABC transporter ABC_trans_N PF14510.6 OAJ13885.1 - 2.2e-09 37.8 0.2 8.6e-09 35.9 0.2 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAJ13885.1 - 3.9e-07 30.6 4.8 0.0039 17.6 0.4 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAJ13885.1 - 3.4e-05 23.5 1.0 0.17 11.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 OAJ13885.1 - 0.00021 20.9 0.3 0.0063 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ13885.1 - 0.00037 20.4 0.1 0.022 14.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 OAJ13885.1 - 0.00045 20.1 0.1 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAJ13885.1 - 0.0029 17.9 0.3 2.2 8.5 0.5 3.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ13885.1 - 0.013 15.5 0.1 10 6.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 OAJ13885.1 - 0.026 15.1 0.0 0.24 12.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ13885.1 - 0.054 13.7 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 AAA domain DUF1088 PF06469.11 OAJ13885.1 - 0.069 12.8 0.8 0.13 11.9 0.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Ploopntkinase3 PF18751.1 OAJ13885.1 - 0.083 12.8 1.8 6.1 6.7 0.0 2.7 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_30 PF13604.6 OAJ13885.1 - 0.098 12.4 6.0 6.1 6.5 2.8 3.7 4 1 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 OAJ13885.1 - 0.14 12.5 0.0 38 4.7 0.1 2.8 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 OAJ13885.1 - 0.14 12.1 0.9 3.2 7.8 0.2 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ13885.1 - 0.21 11.7 2.4 4.1 7.6 0.6 2.9 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 OAJ13885.1 - 9.2 6.1 6.2 9.5 6.1 0.5 3.0 3 0 0 3 3 3 0 NACHT domain NMO PF03060.15 OAJ13886.1 - 5.1e-31 108.3 3.9 1.3e-26 93.8 3.9 3.6 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 OAJ13886.1 - 0.00035 19.7 0.2 0.00099 18.2 0.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAJ13886.1 - 0.049 12.6 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TFIIE-A_C PF11521.8 OAJ13886.1 - 2.1 8.7 4.3 3.3 8.1 0.8 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Clat_adaptor_s PF01217.20 OAJ13887.1 - 4e-09 36.6 0.0 5.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 OAJ13887.1 - 0.029 14.8 0.6 0.045 14.1 0.5 1.3 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4337 PF14235.6 OAJ13887.1 - 0.15 12.1 0.1 0.23 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NUDIX PF00293.28 OAJ13888.1 - 4.2e-06 26.8 0.0 8.6e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RabGAP-TBC PF00566.18 OAJ13889.1 - 1.5e-48 165.3 0.0 2.4e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 OAJ13889.1 - 3.3e-06 27.0 0.0 7.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain RSS_P20 PF11757.8 OAJ13889.1 - 0.078 13.4 0.0 4.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Pan3_PK PF18101.1 OAJ13890.1 - 2.9e-57 192.5 0.0 5.3e-57 191.6 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAJ13890.1 - 0.00027 20.4 0.0 0.0011 18.4 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13890.1 - 0.013 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase TFIIA PF03153.13 OAJ13890.1 - 0.19 11.7 32.2 0.36 10.8 32.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUA5 PF03481.13 OAJ13891.1 - 3.2e-28 98.9 0.0 1.3e-27 97.0 0.0 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Sua5_yciO_yrdC PF01300.18 OAJ13891.1 - 1e-25 90.3 0.0 2.3e-25 89.1 0.0 1.6 1 1 0 1 1 1 1 Telomere recombination LIM PF00412.22 OAJ13892.1 - 1.5e-20 73.1 14.9 9.7e-12 44.9 4.1 3.0 2 1 0 2 2 2 2 LIM domain DUF5319 PF17252.2 OAJ13892.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5319) zf_UBZ PF18439.1 OAJ13892.1 - 4.6 6.9 15.7 1.3 8.7 0.3 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 OAJ13892.1 - 4.8 7.6 10.5 2.4 8.6 0.8 3.4 2 2 0 2 2 2 0 Restriction alleviation protein Lar zf-ACC PF17848.1 OAJ13892.1 - 7.7 6.7 9.5 1.7 8.8 0.0 3.5 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain ATP-synt_D PF01813.17 OAJ13904.1 - 2.3e-72 243.0 3.0 3.4e-72 242.4 3.0 1.3 1 0 0 1 1 1 1 ATP synthase subunit D APG6_N PF17675.1 OAJ13904.1 - 0.41 11.2 5.6 0.91 10.1 5.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region XFP_N PF09364.10 OAJ13905.1 - 5.6e-125 416.9 0.3 4.4e-104 348.2 0.1 2.1 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 OAJ13905.1 - 8.2e-68 227.9 0.0 2.1e-67 226.5 0.0 1.6 1 1 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAJ13905.1 - 1.2e-60 204.2 0.0 1.9e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 OAJ13905.1 - 0.041 13.7 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GrlR PF16518.5 OAJ13905.1 - 0.19 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 T3SS negative regulator,GrlR PI3_PI4_kinase PF00454.27 OAJ13906.1 - 1.8e-51 175.3 0.0 2.9e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAJ13906.1 - 4.3e-29 101.8 0.0 1.4e-28 100.1 0.0 2.0 2 0 0 2 2 2 1 FAT domain UME PF08064.13 OAJ13906.1 - 4.7e-19 68.2 0.0 2e-18 66.2 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 OAJ13906.1 - 2.5e-08 33.6 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 FATC domain DUF3385 PF11865.8 OAJ13906.1 - 0.0054 16.6 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) 4HBT PF03061.22 OAJ13907.1 - 2.5e-16 59.8 0.6 4.8e-11 42.9 0.2 2.6 2 0 0 2 2 2 2 Thioesterase superfamily F-box-like PF12937.7 OAJ13908.1 - 0.085 12.8 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like DRMBL PF07522.14 OAJ13909.1 - 1.4e-26 92.9 0.0 2.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 OAJ13909.1 - 0.013 15.6 0.3 0.032 14.3 0.3 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Cys_rich_CPXG PF14255.6 OAJ13909.1 - 0.059 13.3 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG Lactamase_B_2 PF12706.7 OAJ13909.1 - 0.07 12.6 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Dcc1 PF09724.9 OAJ13909.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Phytase-like PF13449.6 OAJ13910.1 - 3.9e-35 122.2 0.5 5.4e-35 121.7 0.5 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase ArAE_2_N PF10337.9 OAJ13911.1 - 1.8e-64 218.5 0.1 6.6e-64 216.7 0.0 2.0 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 OAJ13911.1 - 1.4e-30 106.8 0.1 3.8e-30 105.4 0.1 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 OAJ13911.1 - 2.5e-08 34.1 20.2 2.5e-08 34.1 20.2 3.8 3 1 0 3 3 3 1 Fusaric acid resistance protein-like Ykof PF07615.11 OAJ13911.1 - 0.025 15.0 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 0 YKOF-related Family Pinin_SDK_N PF04697.13 OAJ13911.1 - 0.025 15.2 3.0 0.1 13.2 3.0 2.0 1 1 0 1 1 1 0 pinin/SDK conserved region DUF5408 PF17402.2 OAJ13911.1 - 0.29 11.0 1.2 0.95 9.4 1.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Fumble PF03630.14 OAJ13912.1 - 3e-125 417.8 0.0 4.4e-125 417.3 0.0 1.2 1 0 0 1 1 1 1 Fumble NUDIX PF00293.28 OAJ13918.1 - 2.1e-11 44.0 0.0 4.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DLIC PF05783.11 OAJ13918.1 - 0.44 9.3 0.7 0.8 8.5 0.7 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Ank_4 PF13637.6 OAJ13919.1 - 0.00017 22.1 0.2 0.00049 20.6 0.1 1.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ13919.1 - 0.00037 21.0 0.0 0.0011 19.5 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ13919.1 - 0.0018 18.6 0.1 0.064 13.7 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAJ13919.1 - 0.054 14.1 0.1 0.43 11.3 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat eIF-6 PF01912.18 OAJ13920.1 - 9.5e-79 263.4 0.3 1.1e-78 263.1 0.3 1.0 1 0 0 1 1 1 1 eIF-6 family SRP54_N PF02881.19 OAJ13921.1 - 0.12 12.6 0.2 1 9.6 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain GP67 PF17634.2 OAJ13921.1 - 7 7.1 12.8 1.5 9.3 0.2 2.7 2 0 0 2 2 2 0 Gene product 67 MRP-S33 PF08293.11 OAJ13922.1 - 1.2e-19 70.4 0.3 6.1e-19 68.0 0.3 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Pex14_N PF04695.13 OAJ13922.1 - 0.11 13.2 8.3 0.16 12.6 8.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim17 PF02466.19 OAJ13923.1 - 8.6e-09 35.8 1.7 8.6e-09 35.8 0.5 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family TRAPPC9-Trs120 PF08626.11 OAJ13924.1 - 5.6e-152 507.7 0.0 7e-150 500.7 0.0 2.8 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TraK PF06586.11 OAJ13924.1 - 0.19 11.4 1.5 1.2 8.7 0.8 2.4 2 0 0 2 2 2 0 TraK protein RCC1 PF00415.18 OAJ13925.1 - 2.7e-06 27.9 2.7 14 6.4 0.0 6.3 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ13925.1 - 0.00015 21.5 10.2 0.042 13.7 0.6 5.4 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 OAJ13925.1 - 0.03 14.2 0.3 0.067 13.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAJ13925.1 - 0.042 13.8 1.0 0.11 12.5 1.0 1.7 1 0 0 1 1 1 0 F-box-like His_Phos_2 PF00328.22 OAJ13926.1 - 1.2e-14 54.5 0.0 1.5e-13 50.9 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NepR PF18557.1 OAJ13926.1 - 1 9.1 3.4 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma factor NepR Catalase PF00199.19 OAJ13929.1 - 1e-158 528.4 0.0 1.3e-158 528.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ13929.1 - 1e-12 48.1 0.0 2.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Disaggr_repeat PF06848.11 OAJ13929.1 - 0.058 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat Pkinase PF00069.25 OAJ13930.1 - 5.7e-72 242.2 0.0 6.5e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13930.1 - 2e-32 112.5 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ13930.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ13930.1 - 0.00072 18.6 0.0 0.001 18.1 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ13930.1 - 0.0012 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ13930.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MTABC_N PF16185.5 OAJ13937.1 - 0.0022 17.5 3.6 0.0039 16.7 3.6 1.4 1 1 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region ABC2_membrane_2 PF12679.7 OAJ13937.1 - 0.78 9.0 8.7 2.1 7.5 8.1 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1179 PF06678.11 OAJ13938.1 - 0.019 14.9 0.4 0.083 12.9 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) ANAPC4_WD40 PF12894.7 OAJ13939.1 - 2.6e-10 40.5 0.0 0.0033 17.7 0.0 4.9 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ13939.1 - 8.3e-10 39.1 6.7 0.027 15.3 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ13939.1 - 5.3e-05 23.6 2.7 0.053 14.0 0.0 4.7 5 1 1 6 6 6 2 PQQ-like domain AdoHcyase PF05221.17 OAJ13940.1 - 7.9e-133 442.2 0.0 3.3e-74 249.7 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAJ13940.1 - 2.7e-83 277.9 2.0 4.1e-83 277.3 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ13940.1 - 1.5e-08 34.2 0.1 3.9e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAJ13940.1 - 0.00062 19.4 0.1 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAJ13940.1 - 0.0037 17.5 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 OAJ13940.1 - 0.092 13.2 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Urocanase PF01175.18 OAJ13940.1 - 0.11 12.2 0.1 0.61 9.7 0.1 2.0 2 0 0 2 2 2 0 Urocanase Rossmann-like domain ABC_membrane PF00664.23 OAJ13942.1 - 5e-41 141.2 17.9 5.3e-25 88.6 3.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ13942.1 - 6.5e-21 75.3 0.3 3.1e-20 73.1 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 OAJ13942.1 - 0.0093 16.4 2.0 0.026 14.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 OAJ13942.1 - 0.094 12.1 0.1 2.4 7.5 0.1 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.6 OAJ13942.1 - 0.12 12.4 0.7 14 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OAJ13942.1 - 7.3 7.0 12.5 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAJ13943.1 - 1.2e-31 110.0 0.0 2.8e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAJ13943.1 - 1.6e-12 47.6 0.2 2.1e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAJ13943.1 - 1.2e-06 28.1 0.6 0.00035 20.1 0.1 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OAJ13943.1 - 9.9e-05 22.5 1.3 0.00034 20.8 0.3 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAJ13943.1 - 0.00044 20.3 0.3 0.001 19.1 0.1 1.7 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAJ13943.1 - 0.00065 19.6 0.2 0.093 12.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ13943.1 - 0.001 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 OAJ13943.1 - 0.0028 16.8 0.0 0.0051 15.9 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 OAJ13943.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 OAJ13943.1 - 0.012 15.9 0.0 0.089 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAJ13943.1 - 0.019 14.9 0.0 0.064 13.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 OAJ13943.1 - 0.021 14.6 1.2 0.13 12.0 0.2 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ13943.1 - 0.022 14.1 0.0 0.057 12.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.6 OAJ13943.1 - 0.046 14.1 2.2 0.072 13.5 0.8 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OAJ13943.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ13943.1 - 0.073 13.6 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ13943.1 - 0.094 12.2 0.1 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 OAJ13943.1 - 0.12 11.3 0.2 0.22 10.4 0.2 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 OAJ13943.1 - 0.12 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 OAJ13943.1 - 0.2 11.3 0.1 0.38 10.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 OAJ13944.1 - 1.1e-09 37.9 0.0 3.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec5 PF15469.6 OAJ13945.1 - 3.6e-55 186.7 2.5 1.5e-54 184.7 0.0 2.8 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAJ13945.1 - 0.012 15.7 0.3 0.07 13.2 0.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 FGGY_C PF02782.16 OAJ13945.1 - 0.09 12.5 0.2 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain RINT1_TIP1 PF04437.13 OAJ13945.1 - 0.94 8.3 7.3 0.17 10.7 0.2 3.1 3 2 1 4 4 4 0 RINT-1 / TIP-1 family Exo84_C PF16528.5 OAJ13945.1 - 1.2 8.9 6.9 0.48 10.2 0.3 3.4 3 1 1 4 4 4 0 Exocyst component 84 C-terminal ADH_N PF08240.12 OAJ13946.1 - 2.1e-28 98.4 0.8 3.9e-28 97.5 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 OAJ13946.1 - 8.8e-07 28.7 3.2 8.8e-07 28.7 3.2 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 OAJ13946.1 - 1.6e-06 28.1 0.2 0.00015 21.8 0.2 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2OG-FeII_Oxy_3 PF13640.6 OAJ13947.1 - 5.5e-06 27.2 0.0 1.1e-05 26.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.11 OAJ13947.1 - 0.086 12.8 0.1 0.33 11.0 0.1 2.0 2 0 0 2 2 2 0 Excisionase-like protein Tubulin PF00091.25 OAJ13949.1 - 1.7e-62 211.1 0.0 2.5e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ13949.1 - 5.6e-36 123.5 0.0 8.2e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ13949.1 - 0.0001 22.6 0.0 0.00056 20.2 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ13949.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ13949.1 - 0.0036 16.5 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin like MIS13 PF08202.11 OAJ13959.1 - 1.5e-16 60.6 0.0 7e-14 51.8 0.0 3.2 2 1 0 2 2 2 2 Mis12-Mtw1 protein family DivIC PF04977.15 OAJ13959.1 - 0.085 12.6 1.6 0.12 12.1 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator DAO PF01266.24 OAJ13960.1 - 3 7.3 4.6 3.1 7.3 4.6 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Phage_holin_3_6 PF07332.11 OAJ13960.1 - 6 6.9 5.7 11 6.0 5.7 1.5 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Esterase PF00756.20 OAJ13961.1 - 3.3e-38 131.7 0.0 4.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OAJ13961.1 - 0.069 12.0 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme SoDot-IcmSS PF16848.5 OAJ13961.1 - 0.24 11.4 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative Gti1_Pac2 PF09729.9 OAJ13962.1 - 4.6e-27 95.3 4.9 3.4e-25 89.2 0.8 6.5 5 1 1 6 6 6 2 Gti1/Pac2 family Frataxin_Cyay PF01491.16 OAJ13963.1 - 8.4e-30 103.0 0.0 1.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain TFIID-18kDa PF02269.16 OAJ13964.1 - 7.4e-32 109.2 0.9 1.3e-30 105.2 0.7 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Proteasome PF00227.26 OAJ13965.1 - 3.2e-30 105.0 0.0 4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Sacchrp_dh_C PF16653.5 OAJ13967.1 - 3.4e-84 283.1 0.0 5.5e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 OAJ13967.1 - 1.1e-64 217.3 0.0 2.4e-64 216.2 0.0 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 OAJ13967.1 - 8.7e-24 84.2 1.2 1.9e-23 83.2 0.3 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 OAJ13967.1 - 1.6e-20 72.7 0.1 3.2e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain NAD_binding_10 PF13460.6 OAJ13967.1 - 0.00046 20.1 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAJ13967.1 - 0.00092 19.6 0.2 0.0041 17.6 0.1 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ13967.1 - 0.0022 18.6 0.0 0.021 15.5 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ13967.1 - 0.0056 17.4 0.2 0.21 12.4 0.1 3.1 2 1 0 2 2 2 1 Methyltransferase domain Shikimate_DH PF01488.20 OAJ13967.1 - 0.021 14.9 0.1 0.29 11.2 0.0 2.8 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAJ13967.1 - 0.042 14.3 0.4 3.4 8.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 OAJ13967.1 - 0.069 14.0 0.4 0.2 12.5 0.1 2.0 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold DnaJ PF00226.31 OAJ13968.1 - 1.9e-15 56.7 0.2 3.4e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Ferric_reduct PF01794.19 OAJ13969.1 - 1.4e-16 60.7 14.9 3.3e-16 59.5 14.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAJ13969.1 - 4.3e-15 55.7 0.0 5.5e-13 49.0 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ13969.1 - 2.4e-09 37.5 0.0 5.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ric8 PF10165.9 OAJ13970.1 - 1.1e-79 268.6 3.6 3.7e-79 266.9 3.6 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF2615 PF11027.8 OAJ13970.1 - 0.13 12.4 0.1 4.3 7.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Troponin PF00992.20 OAJ13970.1 - 5.8 7.2 11.2 14 6.0 11.2 1.6 1 0 0 1 1 1 0 Troponin zn-ribbon_14 PF16503.5 OAJ13983.1 - 1.5e-17 62.8 2.7 1.5e-17 62.8 2.7 3.4 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 OAJ13983.1 - 1.1e-15 57.9 0.0 1.7e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 OAJ13983.1 - 0.0082 15.7 1.7 0.0082 15.7 1.7 3.0 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.16 OAJ13983.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.12 OAJ13983.1 - 0.093 12.3 0.4 0.093 12.3 0.4 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.7 OAJ13983.1 - 0.17 11.9 8.0 6.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Double zinc ribbon RNHCP PF12647.7 OAJ13983.1 - 2.8 8.0 7.3 2.3 8.2 0.2 2.9 3 0 0 3 3 3 0 RNHCP domain MRP-S28 PF10213.9 OAJ13984.1 - 2.1e-25 89.6 0.0 7.7e-25 87.8 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein SR-25 PF10500.9 OAJ13984.1 - 0.53 9.9 13.0 0.88 9.1 13.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SSF PF00474.17 OAJ13986.1 - 1.3e-24 86.8 32.2 1.3e-24 86.8 32.2 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family Sterol_MT_C PF08498.10 OAJ13987.1 - 2.3e-29 101.5 0.7 2.5e-29 101.4 0.7 1.0 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal DUF5349 PF17298.2 OAJ13988.1 - 6.5 6.4 12.3 0.67 9.7 8.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5349) MULE PF10551.9 OAJ13989.1 - 1.4e-21 76.7 0.0 5.3e-21 74.8 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ13989.1 - 2.6e-07 29.8 0.0 4.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 OAJ13989.1 - 0.00047 20.1 2.2 0.00076 19.4 0.8 2.0 2 0 0 2 2 2 1 MuDR family transposase Ribosomal_S7e PF01251.18 OAJ13989.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e DDE_Tnp_IS66_C PF13817.6 OAJ13989.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 IS66 C-terminal element Het-C PF07217.11 OAJ13990.1 - 1.7e-46 158.9 0.1 1.9e-46 158.8 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C NAD_binding_1 PF00175.21 OAJ13992.1 - 5.1e-28 97.9 0.0 1e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAJ13992.1 - 7.2e-20 71.2 0.0 2.4e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAJ13992.1 - 9.6e-08 32.3 0.0 6e-05 23.2 0.0 2.8 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAJ13992.1 - 0.0072 16.5 0.0 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain zf-CCHC PF00098.23 OAJ14002.1 - 5.1e-18 64.2 22.2 1.2e-07 31.5 1.1 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ14002.1 - 0.013 15.2 12.0 0.091 12.5 1.1 3.1 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ14002.1 - 0.017 15.1 12.1 0.25 11.3 0.8 3.2 1 1 2 3 3 3 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ14002.1 - 0.1 12.4 1.1 0.1 12.4 1.1 3.1 4 0 0 4 4 4 0 Zinc knuckle HscB_4_cys PF18256.1 OAJ14002.1 - 0.94 9.3 6.5 2.2 8.2 0.7 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif zf-CCHC_5 PF14787.6 OAJ14002.1 - 1 9.1 12.6 2 8.2 0.8 3.8 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger VCBS PF13517.6 OAJ14003.1 - 5.3e-19 68.6 13.7 7.6e-06 26.4 0.5 5.8 4 2 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OAJ14003.1 - 1.5e-09 37.8 4.5 0.0039 17.3 0.0 5.8 5 1 0 5 5 5 3 FG-GAP repeat Pkinase PF00069.25 OAJ14004.1 - 2e-60 204.4 0.0 1e-34 120.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14004.1 - 1e-22 80.7 0.0 6.1e-20 71.6 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase DUF2461 PF09365.10 OAJ14005.1 - 3.4e-59 200.3 0.0 5.4e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) UCH PF00443.29 OAJ14006.1 - 6.6e-33 114.3 0.0 4.5e-29 101.7 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ14006.1 - 0.00078 19.1 0.0 3.7 7.1 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase FAM176 PF14851.6 OAJ14006.1 - 6.8 6.3 7.6 4 7.1 3.7 2.6 2 0 0 2 2 2 0 FAM176 family SET PF00856.28 OAJ14007.1 - 1.8e-18 67.5 1.7 9e-18 65.2 0.0 2.9 3 0 0 3 3 3 1 SET domain N-SET PF11764.8 OAJ14007.1 - 3.5e-11 43.5 1.4 2.7e-06 27.6 0.2 3.6 3 1 1 4 4 4 2 COMPASS (Complex proteins associated with Set1p) component N ProRS-C_1 PF09180.11 OAJ14008.1 - 3.7e-26 91.1 0.7 7.2e-26 90.2 0.7 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OAJ14008.1 - 1.5e-15 57.1 0.0 3e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ14008.1 - 1.8e-15 57.3 0.0 4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-ZPR1 PF03367.13 OAJ14008.1 - 0.25 11.2 0.8 12 5.7 0.0 2.6 3 0 0 3 3 3 0 ZPR1 zinc-finger domain ChAPs PF09295.10 OAJ14009.1 - 3.6e-151 503.7 0.0 5.3e-151 503.1 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 OAJ14009.1 - 0.00015 22.2 0.2 1.8 9.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14009.1 - 0.0063 16.5 1.5 1.1 9.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ14009.1 - 0.14 12.4 4.7 4.3 7.6 0.1 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AMP-binding PF00501.28 OAJ14010.1 - 2.9e-91 306.2 0.0 3.9e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ14010.1 - 2.1e-08 35.0 0.0 5.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RPN7 PF10602.9 OAJ14011.1 - 1.4e-40 138.9 0.0 3.4e-40 137.6 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ14011.1 - 1.7e-14 54.2 0.0 4.9e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 PCI domain DUF2505 PF10698.9 OAJ14011.1 - 0.15 12.1 0.2 0.4 10.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Pkinase PF00069.25 OAJ14020.1 - 5.8e-43 147.2 0.0 5.3e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14020.1 - 4e-24 85.3 0.0 5.2e-19 68.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14020.1 - 0.043 13.1 0.0 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like LSM PF01423.22 OAJ14021.1 - 8.3e-15 54.2 0.0 1.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ14021.1 - 0.00075 19.6 0.0 0.00088 19.4 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 OAJ14021.1 - 0.066 13.4 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain RT_RNaseH PF17917.1 OAJ14022.1 - 2.5e-36 124.2 0.1 4.8e-36 123.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ14022.1 - 8.6e-36 122.0 0.3 2.6e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ14022.1 - 5.4e-32 111.1 0.1 1.1e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ14022.1 - 2.4e-21 75.6 0.4 6.1e-21 74.3 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ14022.1 - 8.6e-17 61.4 0.0 3.7e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ14022.1 - 0.0012 19.0 0.0 0.0078 16.4 0.0 2.4 2 0 0 2 2 2 1 H2C2 zinc finger Retrotrans_gag PF03732.17 OAJ14023.1 - 5.4e-11 42.6 2.2 7.7e-11 42.1 0.0 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ14023.1 - 1.7e-08 34.3 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 OAJ14023.1 - 1.3e-05 25.7 0.0 3.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ14023.1 - 0.00015 22.3 0.0 0.00045 20.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OAJ14023.1 - 0.0012 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Utp14 PF04615.13 OAJ14024.1 - 0.059 11.9 0.2 0.086 11.4 0.2 1.2 1 0 0 1 1 1 0 Utp14 protein MTABC_N PF16185.5 OAJ14024.1 - 0.2 11.2 0.6 0.31 10.5 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region LptF_LptG PF03739.14 OAJ14024.1 - 0.42 9.4 3.6 0.85 8.4 3.6 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Chromo PF00385.24 OAJ14025.1 - 1.1e-09 38.1 0.0 1.6e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1640 PF07798.11 OAJ14027.1 - 0.068 13.2 0.4 0.13 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) GRP PF07172.11 OAJ14027.1 - 0.58 10.9 9.6 2.3 9.0 6.3 2.9 2 0 0 2 2 2 0 Glycine rich protein family DUF1690 PF07956.11 OAJ14027.1 - 2.4 8.6 8.7 1.2 9.6 5.1 2.1 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Peptidase_S10 PF00450.22 OAJ14028.1 - 1.2e-92 311.5 0.0 1.6e-92 311.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Arrestin_C PF02752.22 OAJ14029.1 - 1.1e-07 32.4 0.0 9.8e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ14029.1 - 0.0024 17.9 0.1 1.6 8.8 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain MAP65_ASE1 PF03999.12 OAJ14041.1 - 1.2e-43 149.8 0.0 2.2e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Tti2 PF10521.9 OAJ14042.1 - 3.1e-20 72.9 0.0 2.6e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 Tti2 family TAP_C PF03943.13 OAJ14043.1 - 4.4e-13 48.6 0.1 8.3e-13 47.8 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 OAJ14043.1 - 4.4e-06 26.3 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 OAJ14043.1 - 2.5e-05 24.5 2.2 0.0012 19.2 0.6 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ14043.1 - 0.067 13.0 1.6 0.78 9.6 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat NTF2 PF02136.20 OAJ14043.1 - 0.09 13.4 0.2 19 5.9 0.2 2.8 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Rubis-subs-bind PF09273.11 OAJ14045.1 - 2.5e-13 50.8 0.1 4.6e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OAJ14045.1 - 5.9e-11 43.0 0.0 1.4e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 SET domain CENP-B_dimeris PF09026.10 OAJ14045.1 - 0.025 15.0 5.7 0.076 13.4 5.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAJ14045.1 - 0.3 11.1 2.1 0.63 10.0 2.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 OAJ14045.1 - 0.38 10.0 6.5 0.64 9.3 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAJ14045.1 - 0.75 9.5 3.2 0.69 9.6 1.4 1.8 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 OAJ14045.1 - 2.9 8.3 9.9 44 4.5 6.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol3_delta2 PF13177.6 OAJ14046.1 - 9.9e-11 41.7 0.0 2.5e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAJ14046.1 - 9.1e-05 22.9 0.2 0.00029 21.3 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAJ14046.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ14046.1 - 0.018 15.3 0.1 0.076 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ14046.1 - 0.022 15.2 0.1 0.093 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_assoc_2 PF16193.5 OAJ14046.1 - 0.03 14.7 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF1254 PF06863.12 OAJ14046.1 - 0.043 13.9 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Rep_fac_C PF08542.11 OAJ14046.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain Rad17 PF03215.15 OAJ14046.1 - 0.045 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RuvB_N PF05496.12 OAJ14046.1 - 0.08 12.7 0.0 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Complex1_LYR PF05347.15 OAJ14047.1 - 0.00015 21.7 0.5 0.00034 20.6 0.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arm PF00514.23 OAJ14047.1 - 0.014 15.5 9.0 0.31 11.1 0.3 4.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Complex1_LYR_2 PF13233.6 OAJ14047.1 - 0.057 14.2 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like ATP-synt_ab PF00006.25 OAJ14048.1 - 5.7e-63 212.4 0.0 5.7e-63 212.4 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ14048.1 - 6.4e-24 84.3 3.0 9.8e-24 83.7 1.8 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 OAJ14048.1 - 0.0064 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAJ14048.1 - 0.007 15.6 0.7 0.017 14.3 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 OAJ14048.1 - 0.01 15.8 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 OAJ14048.1 - 0.023 14.1 0.2 0.04 13.3 0.2 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 OAJ14048.1 - 0.038 13.9 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OAJ14048.1 - 0.049 14.1 0.0 0.29 11.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ14048.1 - 0.053 13.9 1.6 0.11 12.8 0.1 2.3 2 2 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 OAJ14048.1 - 0.19 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 OAJ14048.1 - 0.73 10.2 4.4 0.34 11.2 0.2 2.4 3 0 0 3 3 3 0 AAA domain Arm PF00514.23 OAJ14049.1 - 0.00049 20.0 25.8 1.1 9.4 0.3 10.5 13 0 0 13 13 13 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAJ14049.1 - 0.00052 20.1 12.7 1e+02 3.6 0.0 8.6 8 0 0 8 8 8 0 HEAT repeat V-ATPase_H_N PF03224.14 OAJ14049.1 - 0.035 13.4 0.1 6.9 5.9 0.0 3.3 3 1 0 4 4 4 0 V-ATPase subunit H HEAT_2 PF13646.6 OAJ14049.1 - 3.2 8.2 15.3 4.6 7.7 0.1 6.7 7 3 1 8 8 8 0 HEAT repeats DUF4505 PF14956.6 OAJ14050.1 - 8.5e-30 103.8 0.0 2.6e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) EAF PF09816.9 OAJ14051.1 - 4.8e-14 52.6 0.0 1.6e-13 50.9 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription elongation factor Myc_N PF01056.18 OAJ14051.1 - 0.015 15.3 2.9 0.015 15.3 2.9 2.6 2 0 0 2 2 2 0 Myc amino-terminal region PPP4R2 PF09184.11 OAJ14051.1 - 0.022 14.4 1.0 0.022 14.4 1.0 2.5 2 0 0 2 2 2 0 PPP4R2 BUD22 PF09073.10 OAJ14051.1 - 0.036 13.4 36.7 0.2 10.9 21.0 2.2 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 OAJ14051.1 - 0.22 11.2 45.9 1.1 8.9 28.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 OAJ14051.1 - 0.63 9.4 29.8 0.091 12.1 0.8 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 OAJ14051.1 - 0.67 8.1 42.8 0.056 11.7 9.7 2.1 2 0 0 2 2 2 0 Nop14-like family BAF1_ABF1 PF04684.13 OAJ14051.1 - 0.94 8.5 21.9 0.33 10.0 10.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RNA_pol_3_Rpc31 PF11705.8 OAJ14051.1 - 1.8 8.8 37.1 3.3 7.9 10.5 2.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 OAJ14051.1 - 2.2 7.6 38.5 0.42 10.0 7.6 2.2 2 0 0 2 2 2 0 SDA1 CNDH2_C PF16858.5 OAJ14051.1 - 3.6 7.4 23.1 0.38 10.6 9.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RskA PF10099.9 OAJ14051.1 - 4.5 7.5 29.0 0.9 9.8 14.7 3.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA XRN_M PF17846.1 OAJ14051.1 - 7 5.5 15.4 0.22 10.4 7.9 1.9 2 0 0 2 2 2 0 Xrn1 helical domain SAM_2 PF07647.17 OAJ14060.1 - 2e-08 34.2 0.0 3.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ14060.1 - 1.6e-05 25.2 0.0 3.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 OAJ14060.1 - 0.059 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) IGR PF09597.10 OAJ14060.1 - 0.22 11.6 0.1 0.59 10.3 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Bromodomain PF00439.25 OAJ14061.1 - 3.3e-13 49.5 0.1 8.9e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain SMC_N PF02463.19 OAJ14062.1 - 7.4e-70 234.8 17.2 6.6e-69 231.7 17.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ14062.1 - 2.9e-24 85.6 0.0 8.2e-24 84.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 OAJ14062.1 - 5.4e-12 46.1 0.0 5.4e-12 46.1 0.0 4.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 OAJ14062.1 - 6.1e-12 46.0 8.4 2.3e-05 24.4 0.1 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ14062.1 - 2.7e-10 41.1 10.0 2.7e-10 41.1 10.0 7.6 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 OAJ14062.1 - 9.8e-05 22.0 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain XhlA PF10779.9 OAJ14062.1 - 0.0044 17.2 1.7 0.0044 17.2 1.7 9.4 10 1 2 12 12 12 1 Haemolysin XhlA ABC_tran PF00005.27 OAJ14062.1 - 1.1 9.8 0.0 1.1 9.8 0.0 6.4 4 2 1 5 5 5 0 ABC transporter DUF3573 PF12097.8 OAJ14062.1 - 9.2 5.0 5.9 14 4.3 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) PTCB-BRCT PF12738.7 OAJ14063.1 - 1.6e-28 98.4 4.0 1.1e-17 63.7 0.2 5.2 7 0 0 7 7 7 2 twin BRCT domain BRCT PF00533.26 OAJ14063.1 - 2.1e-24 85.7 0.0 1.2e-11 44.8 0.0 6.4 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAJ14063.1 - 1.5e-19 70.2 0.0 0.0015 18.9 0.0 7.1 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAJ14063.1 - 2e-13 50.1 0.2 1.2e-11 44.4 0.0 3.2 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OAJ14063.1 - 1.6e-07 31.5 0.8 1 9.7 0.0 5.8 5 1 0 5 5 5 2 DNA ligase 3 BRCT domain DUF4745 PF15923.5 OAJ14063.1 - 0.053 13.5 0.7 0.14 12.1 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) PI31_Prot_C PF08577.11 OAJ14063.1 - 0.37 12.0 3.3 0.41 11.9 0.1 2.8 2 0 0 2 2 2 0 PI31 proteasome regulator UPF0183 PF03676.14 OAJ14064.1 - 2e-29 103.1 0.9 1.4e-05 24.6 0.4 5.3 5 1 0 5 5 5 5 Uncharacterised protein family (UPF0183) Thiolase_N PF00108.23 OAJ14065.1 - 0.033 13.5 0.2 0.058 12.7 0.2 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain SCAMP PF04144.13 OAJ14066.1 - 9.8e-42 143.2 11.0 9.8e-31 107.4 2.7 2.1 2 0 0 2 2 2 2 SCAMP family SAE2 PF08573.10 OAJ14066.1 - 0.082 14.0 0.4 0.14 13.3 0.4 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3958 PF13125.6 OAJ14066.1 - 0.96 9.7 5.0 9.3 6.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HSF_DNA-bind PF00447.17 OAJ14067.1 - 2e-30 105.3 0.4 2e-30 105.3 0.4 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 OAJ14067.1 - 1.1e-24 86.7 0.1 2.4e-24 85.6 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain EPL1 PF10513.9 OAJ14067.1 - 0.4 11.0 4.9 0.99 9.8 4.9 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like NDT80_PhoG PF05224.12 OAJ14068.1 - 1.5e-12 48.1 0.5 7.4e-12 45.9 0.5 2.4 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Ank_3 PF13606.6 OAJ14069.1 - 4.6e-12 45.0 0.0 0.00055 20.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ14069.1 - 5.1e-12 46.1 0.0 7.1e-07 29.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ14069.1 - 3.5e-11 43.5 0.0 5.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ14069.1 - 3.9e-11 43.0 0.2 3.6e-07 30.3 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ14069.1 - 2.7e-08 33.9 0.0 0.0026 18.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat DUF2681 PF10883.8 OAJ14070.1 - 0.069 13.6 3.3 0.095 13.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CN_hydrolase PF00795.22 OAJ14072.1 - 2e-06 27.4 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DSHCT PF08148.12 OAJ14080.1 - 5.1e-52 175.8 0.8 1.6e-51 174.2 0.8 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 OAJ14080.1 - 2.5e-40 137.4 0.0 6.4e-40 136.1 0.0 1.8 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 OAJ14080.1 - 2e-25 90.3 2.8 2.9e-25 89.7 2.8 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 OAJ14080.1 - 1.8e-17 63.7 0.0 3.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ14080.1 - 1e-06 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ14080.1 - 2.5e-06 27.8 0.0 6e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ThiF PF00899.21 OAJ14083.1 - 3.8e-64 216.4 0.0 5.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAJ14083.1 - 3.5e-26 91.2 0.1 5.8e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAJ14083.1 - 0.002 18.2 0.1 0.0055 16.8 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 OAJ14083.1 - 0.05 13.5 0.8 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site UDPG_MGDP_dh_N PF03721.14 OAJ14083.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAJ14083.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAJ14083.1 - 0.2 12.3 0.1 0.38 11.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 OAJ14083.1 - 0.27 11.4 1.9 0.5 10.5 1.9 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein GAS PF13851.6 OAJ14084.1 - 0.044 13.1 7.7 0.051 12.9 1.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.6 OAJ14084.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.9 3 1 0 3 3 3 0 Nucleoporin complex subunit 54 DUF1515 PF07439.11 OAJ14084.1 - 0.19 11.8 4.7 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF812 PF05667.11 OAJ14084.1 - 0.43 9.4 8.3 1.7 7.5 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TMPIT PF07851.13 OAJ14084.1 - 0.93 8.7 3.6 1.1 8.4 0.3 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 OAJ14084.1 - 1 9.9 4.9 5.8 7.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Csm1_N PF18504.1 OAJ14084.1 - 1.7 9.0 10.0 0.89 9.9 0.6 2.9 2 0 0 2 2 2 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 OAJ14084.1 - 2.1 8.6 11.6 1.6 9.0 0.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 OAJ14084.1 - 6.4 6.8 11.4 18 5.4 0.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mod_r PF07200.13 OAJ14084.1 - 7.9 6.6 12.2 2.9 8.0 5.0 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HECT PF00632.25 OAJ14085.1 - 7.2e-91 304.9 0.0 1e-90 304.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SMC_ScpB PF04079.16 OAJ14085.1 - 0.039 13.6 0.1 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB Cyt-b5 PF00173.28 OAJ14086.1 - 3e-09 36.9 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3292 PF11696.8 OAJ14088.1 - 3.2e-10 39.0 11.0 3.5e-06 25.7 0.3 4.1 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAJ14088.1 - 0.011 15.5 0.8 0.025 14.3 0.2 1.8 1 1 1 2 2 2 0 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OAJ14088.1 - 0.17 11.9 5.5 0.35 10.8 2.4 2.2 2 0 0 2 2 2 0 Reticulon Spt5_N PF11942.8 OAJ14088.1 - 6.1 7.9 15.7 48 5.0 12.8 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Amino_oxidase PF01593.24 OAJ14089.1 - 5.9e-10 39.0 0.0 9.3e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ14089.1 - 9.5e-09 35.4 0.1 1.8e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ14089.1 - 0.003 16.8 0.1 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ14089.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 OAJ14089.1 - 0.04 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 OAJ14089.1 - 0.045 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ14089.1 - 0.046 12.4 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ14089.1 - 0.047 12.9 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ14089.1 - 0.048 12.7 0.3 0.072 12.2 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAJ14089.1 - 0.057 12.6 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 OAJ14089.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding Peroxidase_2 PF01328.17 OAJ14090.1 - 4.3e-45 154.5 0.0 6.5e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 PH_4 PF15404.6 OAJ14102.1 - 8e-28 97.5 0.0 2.4e-27 95.9 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ14102.1 - 0.0001 22.7 0.1 8.2 7.0 0.1 5.1 6 0 0 6 6 6 2 PH domain RTP1_C1 PF10363.9 OAJ14103.1 - 9.4e-32 109.5 2.0 2.5e-31 108.2 0.1 2.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 OAJ14103.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 OAJ14103.1 - 2.1 8.8 7.7 3.1 8.3 0.0 4.8 5 0 0 5 5 5 0 HEAT repeats TPR_17 PF13431.6 OAJ14104.1 - 0.00047 20.4 0.5 0.55 10.7 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC1 PF12859.7 OAJ14104.1 - 0.0026 18.3 0.5 0.0084 16.7 0.5 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 TPR_1 PF00515.28 OAJ14104.1 - 0.018 14.9 2.0 3 7.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ14104.1 - 0.02 15.1 0.2 15 6.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ14104.1 - 0.047 14.5 9.8 0.1 13.4 0.2 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ14104.1 - 0.062 13.5 0.7 0.29 11.4 0.4 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 OAJ14104.1 - 0.084 13.0 15.8 0.43 10.8 1.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14104.1 - 0.16 12.3 11.8 23 5.3 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ14104.1 - 10 6.2 7.6 1.7 8.6 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ricin_B_lectin PF00652.22 OAJ14105.1 - 0.16 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain ADH_zinc_N_2 PF13602.6 OAJ14106.1 - 2.7e-16 60.8 0.0 6e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ14106.1 - 6.4e-16 58.5 0.2 1e-15 57.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ14106.1 - 1.7e-06 27.9 0.0 1.1e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 OAJ14106.1 - 0.047 13.4 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sad1_UNC PF07738.13 OAJ14107.1 - 6.1e-22 78.0 0.0 1.3e-09 38.2 0.0 3.1 2 1 1 3 3 3 2 Sad1 / UNC-like C-terminal ATG16 PF08614.11 OAJ14107.1 - 0.014 15.6 3.2 0.014 15.6 3.2 5.4 3 2 1 5 5 5 0 Autophagy protein 16 (ATG16) Filament PF00038.21 OAJ14107.1 - 0.32 10.6 26.1 2.3 7.7 2.7 2.6 2 1 0 2 2 2 0 Intermediate filament protein FAM184 PF15665.5 OAJ14107.1 - 0.56 10.0 22.8 1.8 8.3 11.6 2.5 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B UPF0242 PF06785.11 OAJ14107.1 - 1.1 9.3 22.9 0.23 11.6 5.7 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF842 PF05811.13 OAJ14107.1 - 1.2 8.8 4.3 0.61 9.8 0.2 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Baculo_PEP_C PF04513.12 OAJ14107.1 - 1.5 8.8 6.3 7.1 6.7 0.1 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 OAJ14107.1 - 1.8 8.2 33.1 1.6 8.3 1.2 3.4 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF5082 PF16888.5 OAJ14107.1 - 2.9 8.2 16.6 0.48 10.7 6.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) AAA PF00004.29 OAJ14108.1 - 2.1e-14 54.1 0.0 2.3e-13 50.7 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ14108.1 - 2.1e-11 44.5 1.0 1.2e-07 32.3 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OAJ14108.1 - 1.3e-09 38.5 0.0 5.3e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 OAJ14108.1 - 1.2e-05 25.3 1.1 2.1e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 AAA lid domain AAA_19 PF13245.6 OAJ14108.1 - 0.0022 18.3 0.0 0.0063 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 OAJ14108.1 - 0.019 14.2 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 OAJ14108.1 - 0.044 13.7 0.0 0.2 11.5 0.0 2.1 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 OAJ14108.1 - 0.047 12.9 0.1 0.1 11.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 OAJ14108.1 - 0.05 13.8 0.0 0.25 11.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 OAJ14108.1 - 0.081 12.6 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 OAJ14108.1 - 0.086 12.6 6.1 0.25 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 OAJ14108.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAJ14108.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) BUD22 PF09073.10 OAJ14108.1 - 0.14 11.5 21.7 0.012 15.0 17.0 1.5 2 0 0 2 2 2 0 BUD22 RNA_helicase PF00910.22 OAJ14108.1 - 0.15 12.5 0.0 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 OAJ14108.1 - 0.19 11.6 0.0 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Peptidase_M16_C PF05193.21 OAJ14109.1 - 3.1e-39 134.9 0.0 5.8e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAJ14109.1 - 3.4e-39 134.2 0.0 7.2e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2607 PF10795.9 OAJ14109.1 - 0.023 14.8 0.8 0.056 13.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) PXA PF02194.15 OAJ14109.1 - 0.06 13.3 0.2 25 4.8 0.0 3.2 3 0 0 3 3 3 0 PXA domain GPAT_N PF14829.6 OAJ14109.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal ADH_N PF08240.12 OAJ14110.1 - 3.4e-25 88.0 0.8 6.2e-25 87.2 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ14110.1 - 3.3e-22 78.8 0.0 6.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ14110.1 - 4.8e-09 36.0 0.1 0.00097 18.7 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAJ14110.1 - 0.00021 22.4 0.0 0.0005 21.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 OAJ14110.1 - 0.0049 16.1 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAJ14110.1 - 0.0077 15.6 0.4 0.014 14.7 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OAJ14110.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 OAJ14110.1 - 0.035 12.8 0.2 0.047 12.4 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ14110.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ14110.1 - 0.36 11.4 1.8 0.55 10.8 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-oxoacid_dh PF00198.23 OAJ14111.1 - 4.9e-80 268.3 0.6 1.6e-79 266.7 0.0 1.8 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ14111.1 - 1.8e-18 66.1 1.2 3.7e-18 65.1 1.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ14111.1 - 0.00051 19.8 0.0 0.06 13.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 OAJ14111.1 - 0.0072 17.0 0.0 2.5 8.8 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 OAJ14111.1 - 0.022 14.6 0.3 0.044 13.7 0.3 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein LAP1C PF05609.12 OAJ14111.1 - 0.15 11.1 13.6 0.21 10.6 13.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 OAJ14111.1 - 0.46 9.0 29.3 0.64 8.5 29.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 OAJ14111.1 - 1.9 7.3 18.5 3 6.6 18.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAJ14111.1 - 9.2 4.7 15.8 13 4.2 15.8 1.2 1 0 0 1 1 1 0 Macoilin family SPT2 PF08243.11 OAJ14112.1 - 3.5e-13 50.0 32.9 3.5e-13 50.0 32.9 6.2 4 2 1 5 5 5 1 SPT2 chromatin protein DUF1770 PF08589.10 OAJ14113.1 - 6.7e-05 23.8 0.6 6.7e-05 23.8 0.6 2.3 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) UPRTase PF14681.6 OAJ14119.1 - 1.9e-63 213.7 0.0 2.2e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAJ14119.1 - 0.00019 21.0 0.1 0.00035 20.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Abhydrolase_5 PF12695.7 OAJ14120.1 - 0.024 14.4 0.1 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family EamA PF00892.20 OAJ14121.1 - 8.7e-08 32.4 4.0 8.7e-08 32.4 4.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 OAJ14121.1 - 0.00011 21.3 1.4 0.00017 20.7 0.1 1.9 2 0 0 2 2 2 1 Ceramide synthase regulator TPT PF03151.16 OAJ14121.1 - 1.9 7.8 7.6 3.5 6.9 1.3 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family cwf21 PF08312.12 OAJ14122.1 - 4.6e-16 58.7 5.4 4.6e-16 58.7 5.4 2.7 3 0 0 3 3 3 1 cwf21 domain PVL_ORF50 PF07768.11 OAJ14122.1 - 9.6 6.6 13.0 7.3 6.9 10.7 2.1 1 1 1 2 2 2 0 PVL ORF-50-like family AMP-binding PF00501.28 OAJ14123.1 - 3.9e-82 276.1 0.0 5.1e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ14123.1 - 2.6e-14 53.9 0.1 5.5e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4381 PF14316.6 OAJ14125.1 - 0.043 14.0 0.2 0.26 11.5 0.2 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1772 PF08592.11 OAJ14125.1 - 0.099 13.0 8.9 0.54 10.6 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Sec7_N PF12783.7 OAJ14125.1 - 0.11 12.4 2.0 2.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Plant_vir_prot PF01307.17 OAJ14125.1 - 0.23 11.7 1.3 0.72 10.1 0.0 2.5 2 1 1 3 3 3 0 Plant viral movement protein UPF0182 PF03699.13 OAJ14125.1 - 2.2 6.3 10.6 0.067 11.3 4.5 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) MerC PF03203.14 OAJ14125.1 - 3.1 8.3 9.1 0.74 10.3 3.1 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein DEAD PF00270.29 OAJ14126.1 - 5.5e-10 39.3 0.0 8.8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_7 PF12775.7 OAJ14126.1 - 0.0052 16.3 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ14126.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 OAJ14126.1 - 0.057 13.4 0.0 0.67 9.9 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ14126.1 - 0.084 13.1 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF1824 PF08854.10 OAJ14126.1 - 0.13 12.2 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) ABC_tran PF00005.27 OAJ14126.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Methyltransf_11 PF08241.12 OAJ14128.1 - 1.2e-05 25.9 0.2 0.00011 22.8 0.2 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ14128.1 - 0.00016 22.3 1.2 0.0029 18.3 0.5 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ14128.1 - 0.0039 17.0 0.0 0.0088 15.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF3663 PF12404.8 OAJ14128.1 - 0.053 13.6 0.9 0.24 11.4 0.2 2.2 2 0 0 2 2 2 0 Peptidase Methyltransf_12 PF08242.12 OAJ14128.1 - 0.19 12.5 0.1 0.53 11.1 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Wzy_C PF04932.15 OAJ14129.1 - 0.0013 18.4 0.8 1.7 8.3 1.0 2.3 2 0 0 2 2 2 2 O-Antigen ligase DUF4131 PF13567.6 OAJ14129.1 - 0.029 14.0 0.7 0.11 12.2 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) LSM PF01423.22 OAJ14141.1 - 5.4e-11 42.0 0.0 8.7e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 LSM domain ABC_tran PF00005.27 OAJ14142.1 - 1.7e-35 122.6 0.1 1.5e-17 64.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 OAJ14142.1 - 5.2e-14 51.8 5.4 1.3e-13 50.5 5.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OAJ14142.1 - 7.1e-10 38.7 5.0 0.0022 17.5 0.8 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ14142.1 - 1.4e-09 38.2 0.6 0.15 11.8 0.7 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 OAJ14142.1 - 2.5e-07 30.2 3.3 2.5e-07 30.2 3.3 2.4 3 0 0 3 3 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 OAJ14142.1 - 8.2e-06 25.8 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 OAJ14142.1 - 1.1e-05 25.4 2.1 0.11 12.2 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OAJ14142.1 - 1.4e-05 25.5 0.0 0.061 13.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_10 PF13237.6 OAJ14142.1 - 5.3e-05 23.2 8.8 0.00071 19.6 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 OAJ14142.1 - 5.5e-05 23.6 0.0 0.052 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Fer4_6 PF12837.7 OAJ14142.1 - 9.4e-05 22.3 2.5 9.4e-05 22.3 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 OAJ14142.1 - 0.0002 21.1 0.3 0.51 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ14142.1 - 0.00034 20.9 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAJ14142.1 - 0.00045 19.8 0.5 0.0059 16.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_7 PF12838.7 OAJ14142.1 - 0.00065 20.2 9.2 0.0014 19.2 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 OAJ14142.1 - 0.00095 19.1 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 OAJ14142.1 - 0.0014 18.6 0.9 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 OAJ14142.1 - 0.0017 18.1 0.1 0.89 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ14142.1 - 0.0018 18.7 0.3 0.56 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Fer4_9 PF13187.6 OAJ14142.1 - 0.0024 18.0 11.2 0.0051 16.9 11.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 OAJ14142.1 - 0.0031 17.6 13.6 0.0074 16.4 13.6 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.6 OAJ14142.1 - 0.0033 18.0 3.4 0.13 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 OAJ14142.1 - 0.0037 17.3 1.3 0.0037 17.3 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 OAJ14142.1 - 0.0038 17.4 0.3 2.1 8.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ14142.1 - 0.0058 16.6 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_16 PF13484.6 OAJ14142.1 - 0.0082 17.1 0.3 0.0082 17.1 0.3 2.9 2 1 1 3 3 2 1 4Fe-4S double cluster binding domain NB-ARC PF00931.22 OAJ14142.1 - 0.0095 15.1 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 OAJ14142.1 - 0.014 15.6 0.0 9.3 6.6 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 OAJ14142.1 - 0.016 14.8 2.6 0.84 9.2 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirE PF05272.11 OAJ14142.1 - 0.018 14.8 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 OAJ14142.1 - 0.035 14.6 0.7 0.035 14.6 0.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_28 PF13521.6 OAJ14142.1 - 0.037 14.3 2.0 5.6 7.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 OAJ14142.1 - 0.043 13.8 0.8 18 5.4 0.0 3.4 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 OAJ14142.1 - 0.046 13.4 1.4 1.6 8.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 OAJ14142.1 - 0.057 13.1 0.3 12 5.5 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase Septin PF00735.18 OAJ14142.1 - 0.11 11.8 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Septin TniB PF05621.11 OAJ14142.1 - 0.11 11.9 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 OAJ14142.1 - 0.12 13.0 0.1 11 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAJ14142.1 - 0.26 11.3 0.8 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAJ14142.1 - 0.63 10.1 2.5 33 4.6 0.2 3.0 3 1 0 3 3 2 0 50S ribosome-binding GTPase Fer4_4 PF12800.7 OAJ14142.1 - 2.6 8.8 14.6 0.42 11.2 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 OAJ14142.1 - 3.4 8.2 11.6 0.21 12.1 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Hep_59 PF07052.11 OAJ14143.1 - 1.2e-28 99.9 0.9 1.2e-28 99.9 0.9 2.9 3 2 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 RrnaAD PF00398.20 OAJ14144.1 - 5.7e-21 74.8 0.0 1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RNA_pol_Rpb1_5 PF04998.17 OAJ14145.1 - 7.5e-101 337.0 0.1 1.1e-100 336.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 OAJ14145.1 - 3.8e-90 302.4 0.0 5.7e-90 301.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAJ14145.1 - 5.9e-74 247.8 0.0 1.1e-73 247.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 OAJ14145.1 - 6e-59 199.1 0.1 1e-58 198.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 OAJ14145.1 - 5.8e-45 153.1 0.0 1.2e-44 152.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAJ14145.1 - 4.6e-44 149.7 0.8 8.7e-44 148.8 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAJ14145.1 - 3e-36 123.7 0.0 7.5e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAJ14145.1 - 2.1e-22 78.2 255.5 0.0093 16.3 7.4 17.5 9 2 8 20 20 20 18 RNA polymerase Rpb1 C-terminal repeat Evr1_Alr PF04777.13 OAJ14146.1 - 3.5e-28 98.0 0.1 4.7e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Sec39 PF08314.11 OAJ14146.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Secretory pathway protein Sec39 Sedlin_N PF04628.13 OAJ14147.1 - 3.5e-33 114.5 0.0 1.4e-29 102.8 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAJ14147.1 - 6.2e-06 26.2 0.0 8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family TraT PF05818.12 OAJ14147.1 - 0.95 9.1 3.3 1.3 8.7 3.3 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein FAM176 PF14851.6 OAJ14149.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.0 3 0 0 3 3 3 0 FAM176 family Glyco_transf_20 PF00982.21 OAJ14150.1 - 1.7e-186 620.6 0.0 2e-137 458.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 OAJ14150.1 - 0.0022 18.4 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAJ14150.1 - 0.049 13.2 0.1 1.7 8.2 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 RskA PF10099.9 OAJ14151.1 - 0.072 13.4 10.3 0.07 13.4 10.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DEC-1_N PF04625.13 OAJ14151.1 - 0.73 8.8 6.2 0.66 8.9 6.2 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RRM_1 PF00076.22 OAJ14152.1 - 3.5e-08 33.1 0.1 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ14152.1 - 0.0058 16.5 0.2 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF948 PF06103.11 OAJ14152.1 - 0.024 14.9 6.6 0.23 11.7 2.9 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SF3b10 PF07189.11 OAJ14152.1 - 0.14 12.3 0.9 0.52 10.5 0.3 2.0 2 0 0 2 2 2 0 Splicing factor 3B subunit 10 (SF3b10) Chlorosome_CsmC PF11098.8 OAJ14152.1 - 0.16 12.0 7.6 0.075 13.0 5.1 1.8 2 0 0 2 2 2 0 Chlorosome envelope protein C YtxH PF12732.7 OAJ14152.1 - 0.17 12.5 23.9 2.6 8.6 15.1 4.2 3 1 0 3 3 3 0 YtxH-like protein DivIVA PF05103.13 OAJ14152.1 - 0.39 10.8 12.2 0.16 12.1 4.9 2.9 2 0 0 2 2 2 0 DivIVA protein BLOC1_2 PF10046.9 OAJ14152.1 - 0.43 10.9 5.9 4.3 7.7 0.1 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoLp-III PF07464.11 OAJ14152.1 - 0.53 10.4 11.4 0.65 10.1 5.7 3.1 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAJ14152.1 - 3 8.5 14.6 0.9 10.2 7.2 3.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Phasin_2 PF09361.10 OAJ14152.1 - 5.2 7.4 13.5 1.1 9.6 6.6 3.1 3 1 0 3 3 3 0 Phasin protein Apo-CIII PF05778.12 OAJ14152.1 - 5.5 6.7 13.4 14 5.4 3.8 4.3 2 2 1 3 3 3 0 Apolipoprotein CIII (Apo-CIII) REF PF05755.12 OAJ14152.1 - 9.7 6.0 8.5 3.9 7.2 1.6 2.8 2 1 0 2 2 2 0 Rubber elongation factor protein (REF) PCI PF01399.27 OAJ14154.1 - 1.5e-20 73.6 0.0 4.6e-20 72.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAJ14154.1 - 2.1e-11 43.7 0.1 5e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5588 PF17826.1 OAJ14154.1 - 0.0048 15.8 0.5 0.0078 15.1 0.4 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5588) Ribosomal_60s PF00428.19 OAJ14154.1 - 0.065 13.8 10.3 0.071 13.7 3.6 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein TPR_20 PF14561.6 OAJ14154.1 - 0.1 12.9 3.4 0.8 10.1 2.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1748 PF08520.10 OAJ14160.1 - 1.4e-15 56.9 0.0 1.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) TRAPP PF04051.16 OAJ14161.1 - 2.8e-34 117.9 0.0 4.7e-34 117.2 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component ApbA PF02558.16 OAJ14162.1 - 5.6e-28 97.5 0.0 9.1e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAJ14162.1 - 8.2e-26 90.7 0.0 1.5e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.24 OAJ14162.1 - 0.18 11.3 1.4 0.24 11.0 1.4 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase ERO1 PF04137.15 OAJ14163.1 - 3.5e-122 408.0 0.0 2.2e-121 405.4 0.0 1.9 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ATP-grasp_2 PF08442.10 OAJ14164.1 - 1.6e-67 227.0 0.8 2.1e-67 226.6 0.2 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OAJ14164.1 - 1.2e-23 83.7 1.0 2.1e-23 82.8 1.0 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAJ14164.1 - 1.8e-11 43.9 0.5 3.9e-11 42.8 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 OAJ14164.1 - 0.00089 19.1 0.1 0.0024 17.7 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OAJ14164.1 - 0.077 12.5 0.1 0.2 11.1 0.1 1.7 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OAJ14164.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain ANAPC_CDC26 PF10471.9 OAJ14165.1 - 0.00073 20.3 14.8 0.00073 20.3 14.8 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 MHYT PF03707.16 OAJ14166.1 - 5.1e-20 71.4 17.3 2e-07 31.0 0.7 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Peptidase_A22B PF04258.13 OAJ14166.1 - 0.021 14.4 1.0 0.038 13.5 1.0 1.3 1 0 0 1 1 1 0 Signal peptide peptidase DUF2970 PF11174.8 OAJ14166.1 - 0.4 10.6 5.7 12 5.8 1.6 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) FeoB_associated PF12669.7 OAJ14166.1 - 9.8 6.7 7.3 86 3.7 0.0 3.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Fis1_TPR_C PF14853.6 OAJ14167.1 - 4.4e-24 84.3 0.3 6.8e-24 83.7 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAJ14167.1 - 2.4e-13 49.5 0.0 4.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAJ14167.1 - 0.0011 18.9 0.6 0.0032 17.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14167.1 - 0.15 12.7 0.6 0.78 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat COPI_C PF06957.11 OAJ14167.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ESCRT-II PF05871.12 OAJ14168.1 - 6.1e-50 169.1 0.0 6.8e-49 165.7 0.0 1.9 1 1 1 2 2 2 1 ESCRT-II complex subunit SelB-wing_2 PF09106.11 OAJ14168.1 - 0.044 14.0 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix FeoC PF09012.10 OAJ14168.1 - 0.2 11.8 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 FeoC like transcriptional regulator TrkH PF02386.16 OAJ14169.1 - 7.7e-104 347.9 6.9 2.4e-100 336.4 1.3 2.1 2 0 0 2 2 2 2 Cation transport protein Tmemb_9 PF05434.11 OAJ14169.1 - 0.25 11.2 0.7 0.55 10.1 0.1 1.8 2 0 0 2 2 2 0 TMEM9 DUF4834 PF16118.5 OAJ14169.1 - 3 8.9 4.7 3.1 8.8 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) UPF0016 PF01169.19 OAJ14170.1 - 4e-42 142.4 27.6 5.3e-21 74.7 7.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 OAJ14170.1 - 0.00099 18.9 6.1 0.004 16.9 0.4 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump Ion_trans PF00520.31 OAJ14170.1 - 0.0061 15.8 0.1 0.0061 15.8 0.1 1.5 2 0 0 2 2 2 1 Ion transport protein Bac_export_2 PF01312.19 OAJ14170.1 - 0.016 14.4 0.7 0.016 14.4 0.7 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family DUF308 PF03729.13 OAJ14170.1 - 0.083 13.2 13.6 0.15 12.4 1.4 3.3 2 2 1 3 3 3 0 Short repeat of unknown function (DUF308) CobD_Cbib PF03186.13 OAJ14170.1 - 0.17 11.1 3.9 0.1 11.8 0.6 2.0 2 0 0 2 2 2 0 CobD/Cbib protein Mito_carr PF00153.27 OAJ14171.1 - 6.5e-48 160.6 2.8 5.3e-15 55.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LCAT PF02450.15 OAJ14172.1 - 2.6e-89 300.1 0.0 7.6e-88 295.3 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase HLH PF00010.26 OAJ14173.1 - 8.1e-05 22.5 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4268 PF14088.6 OAJ14173.1 - 0.063 13.2 0.4 0.11 12.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) Thioredoxin_11 PF18078.1 OAJ14173.1 - 3.4 7.8 8.7 6.6 6.9 8.7 1.3 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain zf-C3HC4_3 PF13920.6 OAJ14174.1 - 0.00073 19.4 7.8 0.0012 18.7 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ14174.1 - 1 9.4 9.9 1.7 8.7 9.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ14174.1 - 1.6 8.7 10.5 2.7 7.9 10.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ14174.1 - 6 7.3 9.6 9.4 6.7 9.6 1.3 1 0 0 1 1 1 0 Ring finger domain PhzC-PhzF PF02567.16 OAJ14185.1 - 4.6e-37 128.0 0.0 5.5e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 OAJ14185.1 - 0.0009 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.18 OAJ14186.1 - 1.6e-10 40.5 0.0 3.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ14186.1 - 2.7e-08 33.8 8.3 4.4e-08 33.1 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPI_C PF06957.11 OAJ14186.1 - 0.82 8.4 4.5 1.4 7.6 4.5 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 OAJ14186.1 - 4.6 5.4 18.8 9.5 4.4 18.8 1.4 1 0 0 1 1 1 0 CDC45-like protein HsbA PF12296.8 OAJ14187.1 - 2.7e-20 73.0 14.8 2.7e-20 73.0 14.8 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 OAJ14187.1 - 0.036 14.1 8.3 0.07 13.2 8.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mannitol_dh PF01232.23 OAJ14187.1 - 0.041 14.1 1.1 0.053 13.7 1.1 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Glyco_tranf_2_5 PF13712.6 OAJ14187.1 - 0.25 11.0 3.4 2.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase like family Iso_dh PF00180.20 OAJ14188.1 - 1.3e-101 340.2 0.0 1.8e-101 339.8 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Bromodomain PF00439.25 OAJ14189.1 - 1.7e-28 98.5 0.5 1.2e-12 47.7 0.0 3.2 2 1 0 2 2 2 2 Bromodomain BET PF17035.5 OAJ14189.1 - 5.2e-19 68.2 0.2 9.4e-19 67.3 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation FlxA PF14282.6 OAJ14189.1 - 1.3 9.1 4.2 2.9 7.9 0.0 3.2 3 0 0 3 3 3 0 FlxA-like protein F-box-like PF12937.7 OAJ14190.1 - 1.4e-08 34.5 1.5 6.1e-08 32.4 1.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ14190.1 - 8.9e-06 25.5 0.8 1.6e-05 24.7 0.8 1.4 1 0 0 1 1 1 1 F-box domain ORC6 PF05460.13 OAJ14190.1 - 0.72 9.1 7.7 1.5 8.0 1.5 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) CoaE PF01121.20 OAJ14191.1 - 1.3e-57 194.4 0.0 2.1e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 OAJ14191.1 - 0.0033 18.0 0.0 0.031 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ14191.1 - 0.0045 17.1 0.3 0.027 14.6 0.0 2.5 2 2 0 2 2 2 1 AAA domain SKI PF01202.22 OAJ14191.1 - 0.0058 16.8 0.0 0.026 14.7 0.0 2.1 3 0 0 3 3 3 1 Shikimate kinase SRP68 PF16969.5 OAJ14192.1 - 6.4e-58 197.1 35.6 1.1e-46 160.0 15.1 3.7 2 1 1 3 3 3 2 RNA-binding signal recognition particle 68 Abhydro_lipase PF04083.16 OAJ14193.1 - 2e-13 49.7 0.0 3.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ14193.1 - 7.5e-07 29.0 0.3 1.2e-06 28.4 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ14193.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MAD PF05557.13 OAJ14194.1 - 0.0048 15.3 16.5 0.013 13.9 16.5 1.7 1 1 0 1 1 1 1 Mitotic checkpoint protein YscO-like PF16789.5 OAJ14194.1 - 0.17 11.9 17.2 0.069 13.2 10.1 2.7 2 1 1 3 3 3 0 YscO-like protein DUF21 PF01595.20 OAJ14206.1 - 1.6e-36 125.6 0.4 3.2e-36 124.7 0.4 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ14206.1 - 8.2e-09 35.8 0.1 0.014 15.8 0.0 3.5 3 0 0 3 3 3 2 CBS domain Fasciclin PF02469.22 OAJ14207.1 - 5.4e-15 55.7 0.1 1.2e-07 31.9 0.0 4.5 4 0 0 4 4 4 4 Fasciclin domain PIN_4 PF13638.6 OAJ14208.1 - 5.7e-20 71.9 2.9 1.4e-19 70.7 0.1 2.5 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 OAJ14208.1 - 1.6e-07 31.1 0.0 6.7e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 OAJ14208.1 - 0.0012 19.2 0.4 0.084 13.2 0.0 2.9 2 1 0 2 2 2 1 PIN like domain FlgT_N PF16548.5 OAJ14208.1 - 0.13 12.8 1.6 12 6.5 0.2 2.9 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain Tyrosinase PF00264.20 OAJ14209.1 - 1.4e-24 87.6 0.1 1.7e-24 87.3 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase tRNA-synt_2 PF00152.20 OAJ14210.1 - 3.5e-19 69.0 0.0 3.8e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Pantoate_transf PF02548.15 OAJ14213.1 - 1.4e-89 299.9 2.3 1.5e-85 286.7 0.7 2.3 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAJ14213.1 - 0.0014 18.1 1.6 0.0018 17.8 0.2 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase CASP_C PF08172.12 OAJ14215.1 - 1.4e-73 247.3 0.1 1.4e-73 247.3 0.1 3.9 2 1 0 2 2 2 1 CASP C terminal ZapB PF06005.12 OAJ14215.1 - 0.21 12.1 0.0 0.21 12.1 0.0 7.5 5 2 1 6 6 6 0 Cell division protein ZapB CC2D2AN-C2 PF15625.6 OAJ14215.1 - 0.78 9.5 4.7 0.32 10.7 1.4 2.0 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain Shugoshin_N PF07558.11 OAJ14215.1 - 1.2 9.1 5.6 16 5.5 0.4 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 OAJ14215.1 - 2.1 9.0 0.0 2.1 9.0 0.0 9.1 7 2 2 9 9 9 0 SlyX HALZ PF02183.18 OAJ14215.1 - 2.4 8.4 15.4 4 7.7 0.5 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper CPSase_sm_chain PF00988.22 OAJ14216.1 - 4.5e-43 146.1 0.0 7.4e-43 145.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OAJ14216.1 - 5.4e-36 124.1 0.0 1.1e-35 123.1 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAJ14216.1 - 3.4e-06 27.0 0.1 4.4e-05 23.4 0.3 2.3 2 1 0 2 2 2 1 Peptidase C26 Nop53 PF07767.11 OAJ14217.1 - 2.6e-16 60.1 3.3 3e-16 59.8 3.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SAGA-Tad1 PF12767.7 OAJ14230.1 - 5.9e-46 157.1 0.0 2.3e-45 155.2 0.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit 14-3-3 PF00244.20 OAJ14231.1 - 1.8e-108 361.2 4.1 2e-108 361.0 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 OAJ14231.1 - 0.35 11.4 2.6 0.62 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HisKA PF00512.25 OAJ14231.1 - 0.75 9.9 2.5 1.5 8.9 0.2 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Adaptin_N PF01602.20 OAJ14232.1 - 1.2e-123 413.5 6.5 1.4e-123 413.2 6.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAJ14232.1 - 3.4e-42 143.2 0.0 9.8e-42 141.7 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAJ14232.1 - 4e-16 59.3 0.0 1.7e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain Coatomer_g_Cpla PF16381.5 OAJ14232.1 - 0.028 14.5 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 OAJ14232.1 - 0.17 12.2 5.4 1.3 9.4 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat RasGEF_N_2 PF14663.6 OAJ14232.1 - 0.18 12.2 0.4 6.1 7.3 0.1 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_L5_C PF00673.21 OAJ14233.1 - 1.2e-15 57.4 0.0 1.8e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus DUF4573 PF15140.6 OAJ14233.1 - 0.19 11.5 0.1 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4573) Ribosomal_L5 PF00281.19 OAJ14233.1 - 0.21 11.9 0.1 2.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L5 Alg14 PF08660.11 OAJ14234.1 - 6.6e-47 159.7 0.0 2.1e-45 154.8 0.0 2.2 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4713 PF15831.5 OAJ14234.1 - 0.04 14.4 1.2 0.11 12.9 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) CwfJ_C_1 PF04677.15 OAJ14234.1 - 0.11 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 RPA43_OB PF17875.1 OAJ14235.1 - 2.1e-13 51.0 0.0 2.1e-13 51.0 0.0 3.9 3 2 1 4 4 4 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAJ14235.1 - 1.4e-06 28.6 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Atg14 PF10186.9 OAJ14236.1 - 1.3e-09 37.6 3.5 1.3e-09 37.6 3.5 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 OAJ14236.1 - 0.0062 16.6 4.5 0.0062 16.6 4.5 2.0 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein ALO PF04030.14 OAJ14236.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase PhoD PF09423.10 OAJ14237.1 - 4.1e-36 124.7 0.0 7.3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase AAA_22 PF13401.6 OAJ14238.1 - 4.3e-14 52.9 0.0 8.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAJ14238.1 - 2.1e-10 41.2 0.0 5.1e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OAJ14238.1 - 8.9e-07 28.5 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_lid_10 PF17872.1 OAJ14238.1 - 9.4e-05 22.5 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain NACHT PF05729.12 OAJ14238.1 - 0.00035 20.5 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 OAJ14238.1 - 0.00096 18.4 0.0 0.0041 16.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 OAJ14238.1 - 0.0027 18.1 0.3 0.042 14.2 0.3 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAJ14238.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ14238.1 - 0.065 13.6 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 OAJ14238.1 - 0.076 13.0 0.1 0.36 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Cdc6_C PF09079.11 OAJ14238.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain HORMA PF02301.18 OAJ14239.1 - 1.2e-28 100.1 0.0 1.4e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain NIF PF03031.18 OAJ14240.1 - 6.2e-40 136.5 0.0 9.4e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MBF1 PF08523.10 OAJ14242.1 - 0.26 11.8 1.9 4.8 7.7 1.9 2.3 1 1 0 1 1 1 0 Multiprotein bridging factor 1 K_channel_TID PF07941.11 OAJ14242.1 - 0.53 10.8 9.1 0.21 12.0 6.6 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF202 PF02656.15 OAJ14243.1 - 2.1e-05 24.9 4.0 7e-05 23.2 2.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Allene_ox_cyc PF06351.11 OAJ14243.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Med7 PF05983.11 OAJ14253.1 - 1.4e-37 129.7 1.2 2.1e-36 125.8 1.2 2.0 1 1 0 1 1 1 1 MED7 protein TBD PF12845.7 OAJ14253.1 - 0.056 13.3 0.1 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 TBD domain Nairo_nucleo PF02477.15 OAJ14253.1 - 0.27 10.0 0.3 0.38 9.5 0.3 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein XRN_N PF03159.18 OAJ14254.1 - 0.091 12.2 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus RNA_pol_Rpb6 PF01192.22 OAJ14255.1 - 6.4e-16 58.0 0.2 8.9e-16 57.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pkinase PF00069.25 OAJ14256.1 - 1.2e-47 162.5 0.0 1.1e-46 159.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14256.1 - 1.9e-25 89.6 0.0 3.6e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ14256.1 - 0.0082 16.1 0.1 0.029 14.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ14256.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAJ14256.1 - 0.025 13.6 0.1 0.049 12.6 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L12 PF00542.19 OAJ14257.1 - 6.6e-20 71.2 6.6 6.6e-20 71.2 6.6 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OAJ14257.1 - 1e-12 47.5 9.9 1e-12 47.5 9.9 3.7 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain SOG2 PF10428.9 OAJ14257.1 - 0.019 14.2 4.7 0.02 14.1 4.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF520 PF04461.13 OAJ14257.1 - 0.56 10.3 3.5 0.76 9.9 2.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF520) Ribosomal_S14 PF00253.21 OAJ14258.1 - 2.8e-21 75.0 0.2 4.9e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.11 OAJ14258.1 - 0.091 12.5 0.8 0.27 11.0 0.0 2.1 2 1 0 2 2 2 0 QLQ Tautomerase_3 PF14832.6 OAJ14262.1 - 6.9e-39 133.2 0.0 8e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme adh_short_C2 PF13561.6 OAJ14263.1 - 1.2e-60 205.0 2.3 1.5e-60 204.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ14263.1 - 3.5e-45 153.9 1.1 4.6e-45 153.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ14263.1 - 1.1e-11 45.0 0.2 1.7e-11 44.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ14263.1 - 0.005 16.3 0.1 0.019 14.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 OAJ14263.1 - 0.033 13.6 0.3 0.075 12.4 0.2 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ14263.1 - 0.047 14.3 0.2 0.1 13.2 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PATR PF12951.7 OAJ14263.1 - 0.13 12.4 0.9 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Passenger-associated-transport-repeat HATPase_c PF02518.26 OAJ14263.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RIBIOP_C PF04950.12 OAJ14265.1 - 2.9e-103 345.3 0.0 4.3e-103 344.8 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ14265.1 - 1e-21 76.8 0.0 3.7e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 AARP2CN (NUC121) domain PRCH PF03967.13 OAJ14265.1 - 0.22 11.8 2.0 40 4.4 0.0 3.2 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region HA2 PF04408.23 OAJ14266.1 - 3.8e-18 65.7 0.4 2.2e-17 63.3 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ14266.1 - 4.3e-15 56.0 0.1 1.3e-14 54.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAJ14266.1 - 1.1e-09 38.5 0.0 2.4e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OAJ14266.1 - 1.1e-05 25.8 0.5 4.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 OAJ14266.1 - 0.031 14.8 0.1 0.19 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 OAJ14266.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC IPK PF03770.16 OAJ14276.1 - 3.6e-52 177.1 0.0 6.1e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase RNA_pol_3_Rpc31 PF11705.8 OAJ14276.1 - 2.8 8.1 18.2 13 5.9 18.2 2.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NTP_transf_2 PF01909.23 OAJ14277.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF1419 PF07215.11 OAJ14279.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) RNA_pol_Rpb4 PF03874.16 OAJ14281.1 - 5.9e-16 58.9 0.0 3.1e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 SOR_SNZ PF01680.17 OAJ14283.1 - 1.7e-112 374.2 5.4 2.4e-112 373.7 5.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAJ14283.1 - 8.1e-07 28.6 8.5 3e-05 23.5 0.8 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAJ14283.1 - 0.00064 18.9 0.3 0.88 8.6 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 OAJ14283.1 - 0.0034 17.4 0.3 0.014 15.4 0.0 2.1 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAJ14283.1 - 0.047 13.1 5.2 0.53 9.6 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase DUF726 PF05277.12 OAJ14284.1 - 1.4e-119 399.1 3.6 1.9e-119 398.6 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) WD40 PF00400.32 OAJ14285.1 - 0.038 14.9 0.1 2.2 9.3 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DLH PF01738.18 OAJ14286.1 - 1.6e-19 70.4 0.0 1.9e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Sec61_beta PF03911.16 OAJ14296.1 - 4.7e-17 61.7 0.7 6e-17 61.4 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family DUF4219 PF13961.6 OAJ14297.1 - 5.2e-05 22.8 0.2 9.9e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UQ_con PF00179.26 OAJ14298.1 - 8.3e-50 168.1 0.0 9.9e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ14298.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B Ribosomal_60s PF00428.19 OAJ14298.1 - 0.061 13.9 2.1 0.086 13.4 2.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acetyltransf_1 PF00583.25 OAJ14299.1 - 5.8e-14 52.3 0.0 6.7e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ14299.1 - 3.4e-08 33.5 0.0 3.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ14299.1 - 1.5e-06 28.5 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ14299.1 - 0.00093 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ14299.1 - 0.0012 19.0 0.1 0.0017 18.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_1 PF00515.28 OAJ14300.1 - 7e-12 44.6 3.1 0.00049 19.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14300.1 - 2.1e-10 39.9 3.3 0.0014 18.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ14300.1 - 2.7e-06 27.5 2.1 4.2e-06 26.9 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAJ14300.1 - 2.7e-06 27.8 0.9 0.00063 20.2 0.6 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14300.1 - 0.00016 21.9 1.0 0.0011 19.3 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ14300.1 - 0.00094 19.8 1.1 0.055 14.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ14300.1 - 0.0035 18.0 4.8 3.5 8.7 0.0 3.4 1 1 3 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ14300.1 - 0.024 15.0 1.0 3.5 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14300.1 - 0.036 14.7 3.7 2.3 9.0 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ14300.1 - 0.051 13.3 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 OAJ14300.1 - 0.1 12.7 1.3 1.8 8.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_8 PF14716.6 OAJ14300.1 - 0.33 11.4 3.8 5.7 7.4 0.1 2.6 1 1 1 2 2 2 0 Helix-hairpin-helix domain ParA PF10609.9 OAJ14301.1 - 1e-67 228.2 0.0 3.4e-66 223.2 0.0 2.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ14301.1 - 3.3e-10 40.1 0.4 2.2e-08 34.2 0.4 2.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAJ14301.1 - 1.3e-06 28.4 0.3 6.7e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 OAJ14301.1 - 0.00021 21.2 0.2 0.039 13.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAJ14301.1 - 0.00097 18.8 0.1 0.0023 17.5 0.1 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OAJ14301.1 - 0.001 18.4 0.1 0.0062 15.9 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 OAJ14301.1 - 0.011 14.9 0.4 0.2 10.8 0.2 2.4 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.18 OAJ14301.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TFIIA PF03153.13 OAJ14302.1 - 0.0029 17.7 12.2 0.0088 16.1 12.6 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2205 PF10224.9 OAJ14303.1 - 1.8e-12 47.1 0.0 2.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 OAJ14303.1 - 0.0002 22.0 0.1 0.00024 21.7 0.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA Metallophos PF00149.28 OAJ14304.1 - 7.9e-36 124.5 0.1 1.2e-35 123.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ14304.1 - 0.075 13.5 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 OAJ14304.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Retrotran_gag_2 PF14223.6 OAJ14305.1 - 0.0039 16.9 0.2 0.0061 16.2 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ14305.1 - 0.051 13.9 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein UNC45-central PF11701.8 OAJ14305.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Cyclin_C_2 PF16899.5 OAJ14306.1 - 9.1e-12 45.3 0.7 6.9e-09 36.0 0.4 3.1 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 OAJ14306.1 - 1.5e-08 34.4 0.0 2.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ14306.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Retrotrans_gag PF03732.17 OAJ14307.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein ALS_ss_C PF10369.9 OAJ14309.1 - 9.9e-19 67.3 0.1 2.6e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAJ14309.1 - 5e-13 48.6 0.1 9.2e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OAJ14309.1 - 1.1e-07 31.6 0.1 3.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 ACT domain Zn_clus PF00172.18 OAJ14310.1 - 3.8e-05 23.7 9.6 6e-05 23.1 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GRP PF07172.11 OAJ14310.1 - 0.011 16.4 6.0 0.011 16.4 6.0 4.4 5 0 0 5 5 5 0 Glycine rich protein family Fer4 PF00037.27 OAJ14311.1 - 3e-14 52.1 16.4 2.1e-08 33.6 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAJ14311.1 - 7e-13 48.9 10.4 1.1e-12 48.3 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAJ14311.1 - 3.7e-10 40.6 8.7 2.9e-05 24.9 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAJ14311.1 - 2.2e-09 37.3 6.8 0.00017 21.6 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAJ14311.1 - 1.2e-08 34.9 21.6 3.9e-06 26.9 12.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAJ14311.1 - 1.5e-08 34.7 10.2 2.5e-08 33.9 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ14311.1 - 1.8e-08 34.7 3.1 0.00024 21.5 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 OAJ14311.1 - 6e-07 29.3 17.8 0.00048 20.1 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OAJ14311.1 - 2e-06 27.5 12.5 0.0033 17.4 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAJ14311.1 - 1.6e-05 25.0 11.8 0.00061 20.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAJ14311.1 - 0.00033 21.1 11.3 0.03 14.8 12.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 OAJ14311.1 - 0.0041 17.6 12.5 0.24 12.0 1.1 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAJ14311.1 - 0.019 15.2 5.1 1.4 9.2 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAJ14311.1 - 0.076 13.2 8.9 1.4 9.1 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAJ14311.1 - 0.3 12.1 16.3 0.42 11.7 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 OAJ14311.1 - 0.5 10.5 6.0 2.8 8.1 0.8 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 OAJ14311.1 - 0.54 11.1 11.6 2.5 9.0 1.5 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain EPF PF17181.4 OAJ14311.1 - 2.1 8.4 6.9 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins FYVE PF01363.21 OAJ14312.1 - 2.7e-18 65.9 0.1 5.3e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 OAJ14312.1 - 2.4e-09 36.8 2.2 2.4e-09 36.8 2.2 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Zn-C2H2_12 PF18112.1 OAJ14312.1 - 0.032 14.7 0.3 1 9.9 0.0 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Ribosomal_S27e PF01667.17 OAJ14312.1 - 1.5 8.6 5.0 4.1 7.2 4.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 FYVE_2 PF02318.16 OAJ14312.1 - 1.8 8.8 7.1 1.8 8.8 0.4 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger Prefoldin_2 PF01920.20 OAJ14313.1 - 2e-22 79.1 15.4 2.7e-22 78.7 15.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 OAJ14313.1 - 0.0033 17.9 10.4 0.073 13.5 1.9 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 OAJ14313.1 - 0.0039 16.6 1.4 0.0039 16.6 1.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 OAJ14313.1 - 0.014 15.9 18.2 0.091 13.3 6.7 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region GLYCAM-1 PF05242.11 OAJ14313.1 - 0.021 14.9 3.8 0.028 14.6 3.8 1.2 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) FPP PF05911.11 OAJ14313.1 - 0.024 12.8 11.7 0.031 12.5 11.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Vac_Fusion PF02346.16 OAJ14313.1 - 0.025 14.2 2.4 0.57 9.8 0.8 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Spc7 PF08317.11 OAJ14313.1 - 0.031 13.1 16.0 0.043 12.7 16.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 OAJ14313.1 - 0.049 13.8 13.0 0.56 10.5 2.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nas2_N PF18265.1 OAJ14313.1 - 0.083 12.8 4.1 0.49 10.4 0.1 3.0 2 2 0 2 2 2 0 Nas2 N_terminal domain Cep57_MT_bd PF06657.13 OAJ14313.1 - 0.11 13.0 11.3 0.64 10.5 4.0 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SlyX PF04102.12 OAJ14313.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.5 2 1 0 2 2 2 0 SlyX Fib_alpha PF08702.10 OAJ14313.1 - 0.14 12.3 14.0 1.6 8.9 14.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Macoilin PF09726.9 OAJ14313.1 - 0.16 10.5 14.5 0.21 10.1 14.5 1.1 1 0 0 1 1 1 0 Macoilin family BRE1 PF08647.11 OAJ14313.1 - 0.16 12.0 16.6 0.96 9.6 5.6 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AATF-Che1 PF13339.6 OAJ14313.1 - 0.24 12.1 8.0 0.41 11.3 7.9 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor kleA_kleC PF17383.2 OAJ14313.1 - 0.27 11.6 2.9 0.49 10.7 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A FliD_C PF07195.12 OAJ14313.1 - 0.28 10.6 11.1 1.7 8.0 11.1 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus UPF0242 PF06785.11 OAJ14313.1 - 0.32 11.1 17.2 0.5 10.4 17.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lzipper-MIP1 PF14389.6 OAJ14313.1 - 0.39 11.0 11.3 1.7 9.0 8.9 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Fucose_iso_N2 PF07882.12 OAJ14313.1 - 0.41 10.2 2.8 0.5 9.9 2.8 1.1 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Spc42p PF11544.8 OAJ14313.1 - 0.46 10.5 10.4 1.6 8.8 0.8 2.5 2 1 0 2 2 2 0 Spindle pole body component Spc42p Mto2_bdg PF12808.7 OAJ14313.1 - 0.5 10.7 11.0 2.8 8.3 0.2 3.4 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region KMP11 PF03037.16 OAJ14313.1 - 0.52 11.1 7.3 2.1 9.2 7.3 2.0 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1664 PF07889.12 OAJ14313.1 - 0.58 10.2 9.5 1.5 8.9 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2205 PF10224.9 OAJ14313.1 - 0.61 10.1 16.5 0.05 13.6 4.0 2.4 1 1 1 2 2 2 0 Short coiled-coil protein Seadorna_VP6 PF07407.11 OAJ14313.1 - 0.61 9.0 2.3 0.7 8.8 2.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein GAS PF13851.6 OAJ14313.1 - 0.63 9.4 20.3 5.6 6.3 20.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 OAJ14313.1 - 0.64 10.1 6.7 0.98 9.5 0.8 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 OAJ14313.1 - 0.66 10.7 8.7 2.4 8.9 2.3 2.2 1 1 1 2 2 2 0 Occludin homology domain HR1 PF02185.16 OAJ14313.1 - 0.71 10.0 11.5 1.3 9.2 1.2 2.5 2 1 0 2 2 2 0 Hr1 repeat Tmpp129 PF10272.9 OAJ14313.1 - 0.75 9.0 4.5 0.46 9.7 0.7 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Uso1_p115_C PF04871.13 OAJ14313.1 - 0.85 10.0 16.8 0.65 10.4 2.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region JIP_LZII PF16471.5 OAJ14313.1 - 0.86 9.8 9.9 0.17 12.1 0.9 2.6 2 2 0 2 2 2 0 JNK-interacting protein leucine zipper II Uds1 PF15456.6 OAJ14313.1 - 0.89 9.7 10.4 1.7 8.8 10.4 1.6 1 1 0 1 1 1 0 Up-regulated During Septation YabA PF06156.13 OAJ14313.1 - 0.9 10.2 12.2 1.1 9.9 4.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FlxA PF14282.6 OAJ14313.1 - 0.93 9.5 17.9 0.63 10.1 3.0 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF5082 PF16888.5 OAJ14313.1 - 1.1 9.6 12.1 4.2 7.7 12.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) PKcGMP_CC PF16808.5 OAJ14313.1 - 1.2 9.1 8.1 0.24 11.3 2.2 2.5 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlaC_arch PF05377.11 OAJ14313.1 - 1.3 9.4 10.0 6.5 7.2 2.6 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 OAJ14313.1 - 1.5 8.8 17.1 1.1 9.3 6.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 OAJ14313.1 - 1.5 9.1 14.8 2 8.7 7.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) V-ATPase_C PF03223.15 OAJ14313.1 - 1.7 8.0 8.9 3.8 6.8 8.9 1.6 1 1 0 1 1 1 0 V-ATPase subunit C CLZ PF16526.5 OAJ14313.1 - 2 8.8 11.0 5.6 7.4 0.6 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels End3 PF12761.7 OAJ14313.1 - 2.8 8.1 13.2 3.6 7.7 13.2 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Cob_adeno_trans PF01923.18 OAJ14313.1 - 3.5 7.8 5.9 19 5.4 5.9 1.9 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Prefoldin PF02996.17 OAJ14313.1 - 3.6 7.5 16.3 1.4 8.9 5.0 2.8 1 1 2 3 3 3 0 Prefoldin subunit ABC_tran_CTD PF16326.5 OAJ14313.1 - 3.8 7.8 16.4 8.6 6.7 4.4 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF724 PF05266.14 OAJ14313.1 - 3.9 7.3 15.4 1.3 8.8 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Peptidase_S46 PF10459.9 OAJ14313.1 - 4 6.0 10.0 4.8 5.7 10.0 1.0 1 0 0 1 1 1 0 Peptidase S46 DHR10 PF18595.1 OAJ14313.1 - 4 7.5 18.6 28 4.8 18.6 2.0 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Atg14 PF10186.9 OAJ14313.1 - 4.5 6.3 12.8 14 4.6 12.8 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 OAJ14313.1 - 5.1 7.4 16.7 2.5 8.4 5.2 2.2 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Allexi_40kDa PF05549.11 OAJ14313.1 - 7.1 6.1 6.7 4.5 6.7 2.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein MtrG PF04210.13 OAJ14313.1 - 7.1 6.6 8.4 12 5.8 1.2 3.1 2 2 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G HAUS6_N PF14661.6 OAJ14313.1 - 7.7 6.0 13.0 1.2 8.7 4.9 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus CENP-H PF05837.12 OAJ14313.1 - 7.9 6.9 14.0 7.9 6.9 12.2 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MCU PF04678.13 OAJ14313.1 - 9 6.4 9.5 34 4.5 7.9 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Ribosomal_L5_C PF00673.21 OAJ14314.1 - 2.5e-20 72.4 0.0 4.6e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAJ14314.1 - 2.7e-19 69.3 0.0 5e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 SAPS PF04499.15 OAJ14315.1 - 4.5 5.9 7.8 5.4 5.7 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Fer2 PF00111.27 OAJ14316.1 - 1.2e-11 44.4 0.2 2e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Metallophos PF00149.28 OAJ14328.1 - 3.4e-37 128.9 0.2 5.3e-37 128.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAJ14328.1 - 0.0042 16.7 0.0 0.0066 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 OAJ14328.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF155 PF02582.14 OAJ14329.1 - 1.1e-46 159.2 0.0 1.6e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helo_like_N PF17111.5 OAJ14329.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins BUD22 PF09073.10 OAJ14329.1 - 4.2 6.6 28.1 0.95 8.7 12.1 2.2 2 0 0 2 2 2 0 BUD22 Atg14 PF10186.9 OAJ14330.1 - 3.6e-10 39.4 17.8 1.5e-08 34.2 0.0 3.3 3 0 0 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 Cys_knot PF00007.22 OAJ14330.1 - 0.0033 17.7 0.4 0.0056 17.0 0.4 1.3 1 0 0 1 1 1 1 Cystine-knot domain MIP PF00230.20 OAJ14331.1 - 1e-41 143.1 13.6 1.3e-41 142.8 13.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Cgr1 PF03879.14 OAJ14332.1 - 2.5e-15 56.8 22.4 2.8e-15 56.6 22.4 1.0 1 0 0 1 1 1 1 Cgr1 family PEARLI-4 PF05278.12 OAJ14332.1 - 0.1 12.2 12.5 0.12 12.0 12.5 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pilt PF15453.6 OAJ14332.1 - 0.2 11.0 4.9 0.23 10.8 4.9 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions APG6_N PF17675.1 OAJ14332.1 - 0.57 10.7 10.5 0.67 10.5 10.5 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Fungal_trans PF04082.18 OAJ14334.1 - 1.5e-17 63.5 0.0 1.1e-16 60.7 0.0 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ14334.1 - 1.3e-08 34.8 10.1 2.8e-08 33.8 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-F_N PF10481.9 OAJ14334.1 - 0.012 15.2 0.8 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF1003 PF06210.11 OAJ14334.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF4692 PF15763.5 OAJ14334.1 - 0.49 10.8 4.0 1.7 9.1 4.0 1.9 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) AAA PF00004.29 OAJ14335.1 - 6.5e-41 139.9 0.0 1e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ14335.1 - 1.3e-10 41.1 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ14335.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ14335.1 - 1.2e-05 25.5 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ14335.1 - 2.9e-05 23.4 0.0 6.1e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ14335.1 - 3.9e-05 23.9 0.4 0.033 14.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 OAJ14335.1 - 0.0004 20.8 0.3 0.0089 16.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAJ14335.1 - 0.00097 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ14335.1 - 0.001 19.1 0.4 0.0074 16.3 0.3 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 OAJ14335.1 - 0.0011 18.6 1.5 0.0044 16.6 0.0 2.7 3 0 0 3 3 3 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 OAJ14335.1 - 0.0053 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ14335.1 - 0.0054 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAJ14335.1 - 0.0059 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAJ14335.1 - 0.0062 15.9 0.1 0.22 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.6 OAJ14335.1 - 0.015 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ14335.1 - 0.024 14.2 0.6 2.6 7.6 0.1 2.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ14335.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAJ14335.1 - 0.052 12.8 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OAJ14335.1 - 0.073 13.3 0.3 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ14335.1 - 0.088 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OAJ14335.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAJ14335.1 - 0.13 12.2 0.2 0.79 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 OAJ14335.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ14335.1 - 0.2 11.4 2.3 0.35 10.6 0.3 2.2 2 1 0 2 2 2 0 AAA domain PLU-1 PF08429.11 OAJ14336.1 - 2.5e-49 168.3 3.4 4.2e-49 167.6 3.4 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 OAJ14336.1 - 8.6e-43 145.4 0.3 2.2e-42 144.1 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 OAJ14336.1 - 5e-21 74.3 44.3 9.5e-13 47.8 2.8 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.21 OAJ14336.1 - 4.4e-17 62.5 0.0 8.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 OAJ14336.1 - 1.4e-14 54.2 0.6 1.4e-14 54.2 0.6 2.5 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 OAJ14336.1 - 6.4e-13 48.4 0.8 1.7e-12 47.0 0.8 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 OAJ14336.1 - 4 7.8 18.2 2.6 8.3 0.1 3.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain Peptidase_S10 PF00450.22 OAJ14337.1 - 4.2e-63 214.2 0.2 1.5e-45 156.4 0.3 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase E1_dh PF00676.20 OAJ14338.1 - 3.9e-84 282.1 0.0 5e-84 281.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ14338.1 - 0.14 11.3 0.0 0.39 9.9 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Gpr1_Fun34_YaaH PF01184.19 OAJ14339.1 - 3.7e-86 288.0 16.9 4.5e-86 287.7 16.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Arrestin_N PF00339.29 OAJ14347.1 - 3.5e-05 23.9 0.0 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 OAJ14348.1 - 7.6e-26 91.0 0.0 1.6e-09 37.6 0.0 4.4 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14348.1 - 1.2e-15 57.6 0.0 2e-13 50.2 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Cep57_MT_bd PF06657.13 OAJ14349.1 - 0.055 13.9 0.9 0.055 13.9 0.9 3.9 3 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 LOH1CR12 PF10158.9 OAJ14349.1 - 0.084 12.9 1.2 0.3 11.1 0.9 2.2 1 1 0 1 1 1 0 Tumour suppressor protein NPV_P10 PF05531.12 OAJ14349.1 - 9.6 6.8 11.2 5.2 7.6 0.5 4.2 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Tyrosinase PF00264.20 OAJ14352.1 - 0.0001 22.7 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Adaptin_N PF01602.20 OAJ14353.1 - 4.5e-09 35.4 0.0 5.4e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region TPR_12 PF13424.6 OAJ14354.1 - 0.011 16.0 4.8 3.3 8.1 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ14354.1 - 0.037 13.9 5.6 0.17 11.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 OAJ14354.1 - 0.068 13.4 0.6 0.21 11.9 0.3 2.2 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_8 PF13181.6 OAJ14354.1 - 0.069 13.4 1.4 11 6.6 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ14354.1 - 0.21 11.7 1.6 7.2 6.8 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 SARAF PF06682.12 OAJ14356.1 - 1.8e-63 215.2 10.2 3.5e-63 214.3 10.2 1.4 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis FAM209 PF15206.6 OAJ14356.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 FAM209 family TPR_10 PF13374.6 OAJ14359.1 - 2.2e-37 125.9 52.1 3.7e-05 23.4 0.1 12.7 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14359.1 - 4.3e-30 103.8 53.4 4.1e-06 27.0 0.5 11.0 5 3 6 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14359.1 - 1e-08 34.7 19.5 3 8.2 0.3 11.1 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ14359.1 - 4.3e-06 26.5 12.8 1.9 8.9 0.1 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ14359.1 - 5e-05 23.5 19.2 2.8 8.8 0.1 9.8 10 0 0 10 10 10 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAJ14359.1 - 0.00085 18.2 1.5 38 2.9 0.0 6.0 6 1 0 6 6 6 0 Fungal protein kinase DUF4754 PF15946.5 OAJ14359.1 - 0.0022 18.2 11.1 0.19 12.1 0.3 4.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4754) DUF3856 PF12968.7 OAJ14359.1 - 0.0039 17.3 19.8 0.1 12.7 0.6 5.4 2 2 4 7 7 7 2 Domain of Unknown Function (DUF3856) DUF668 PF05003.12 OAJ14359.1 - 0.0049 17.3 4.7 9.5 6.8 0.0 6.2 3 2 1 5 5 5 1 Protein of unknown function (DUF668) DOG1 PF14144.6 OAJ14359.1 - 0.032 14.5 5.5 15 5.9 0.0 5.4 3 2 4 7 7 7 0 Seed dormancy control DUF2518 PF10726.9 OAJ14359.1 - 0.056 13.1 1.4 12 5.5 0.0 3.2 3 0 0 3 3 3 0 Protein of function (DUF2518) Hydant_A_N PF05378.13 OAJ14359.1 - 0.074 12.7 0.2 45 3.7 0.0 3.8 2 2 2 4 4 4 0 Hydantoinase/oxoprolinase N-terminal region DUF5633 PF18656.1 OAJ14359.1 - 0.078 12.9 1.5 10 6.1 0.2 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5633) KIP1 PF07765.12 OAJ14359.1 - 5.4 7.2 8.1 38 4.5 0.0 5.5 7 0 0 7 7 7 0 KIP1-like protein TPR_10 PF13374.6 OAJ14360.1 - 8.5e-23 79.5 21.5 0.003 17.4 0.0 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14360.1 - 1.3e-18 67.0 31.7 6.4e-05 23.2 0.6 9.8 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14360.1 - 3.3e-06 26.8 10.2 5.3 7.4 0.1 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAJ14360.1 - 0.00023 21.1 1.8 0.055 13.4 0.1 4.1 4 0 0 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 OAJ14360.1 - 0.0015 19.2 21.3 15 6.7 0.1 9.8 10 2 2 12 12 12 1 Tetratricopeptide repeat Gcn1_N PF12074.8 OAJ14360.1 - 0.0072 15.7 0.4 2.5 7.3 0.5 2.2 2 0 0 2 2 2 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal AD PF09793.9 OAJ14360.1 - 0.0079 16.3 0.3 0.36 11.0 0.0 3.5 4 0 0 4 4 4 1 Anticodon-binding domain TPR_1 PF00515.28 OAJ14360.1 - 0.021 14.6 5.2 14 5.7 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat ThiD2 PF17792.1 OAJ14360.1 - 0.19 12.2 2.4 0.77 10.2 0.0 3.0 4 0 0 4 4 4 0 ThiD2 family TPR_7 PF13176.6 OAJ14360.1 - 0.22 11.7 9.6 59 4.0 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14360.1 - 1.9 9.3 13.6 20 6.1 0.0 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat Muskelin_N PF06588.11 OAJ14371.1 - 3e-43 148.0 0.0 7.8e-34 117.3 0.0 2.2 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_5 PF13854.6 OAJ14371.1 - 2e-12 46.8 1.8 0.0023 17.9 0.0 6.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OAJ14371.1 - 5.7e-10 39.2 17.1 4.7e-05 23.6 0.5 7.7 7 1 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ14371.1 - 6e-09 35.9 4.9 0.18 12.1 0.0 6.6 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OAJ14371.1 - 6.3e-07 28.9 11.6 0.00013 21.4 0.3 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 OAJ14371.1 - 0.00064 19.7 13.1 0.031 14.3 0.1 6.1 6 1 0 6 6 6 1 Galactose oxidase, central domain NOA36 PF06524.12 OAJ14371.1 - 8.2 5.6 5.3 14 4.9 5.3 1.3 1 0 0 1 1 1 0 NOA36 protein Ni_hydr_CYTB PF01292.20 OAJ14372.1 - 0.025 14.2 2.8 0.039 13.6 2.8 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4834 PF16118.5 OAJ14372.1 - 0.55 11.2 2.8 0.75 10.8 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4293 PF14126.6 OAJ14372.1 - 1.5 9.1 4.7 0.56 10.4 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) RNA12 PF10443.9 OAJ14373.1 - 2.3e-127 425.4 2.8 4.5e-127 424.5 2.8 1.5 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 OAJ14373.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Amino_oxidase PF01593.24 OAJ14374.1 - 3.6e-13 49.6 0.5 7.3e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ14374.1 - 5.1e-12 45.8 0.1 5.1e-12 45.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ14374.1 - 0.00017 21.3 0.8 0.00017 21.3 0.8 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ14374.1 - 0.0019 17.3 0.2 0.0019 17.3 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAJ14374.1 - 0.0056 16.7 0.3 0.19 11.7 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ14374.1 - 0.012 14.9 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 OAJ14375.1 - 1.2e-50 171.7 0.5 1.5e-50 171.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ14375.1 - 6.2e-35 120.9 0.1 7.9e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ14375.1 - 2.3e-15 57.0 0.1 2.9e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAJ14375.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 OAJ14375.1 - 0.0033 17.3 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ14375.1 - 0.0033 16.8 0.1 0.0071 15.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAJ14375.1 - 0.012 15.1 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ14375.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAJ14375.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DNA_binding_1 PF01035.20 OAJ14375.1 - 0.065 13.4 0.1 0.91 9.7 0.0 2.4 3 0 0 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain ATP_bind_3 PF01171.20 OAJ14376.1 - 2.5e-35 121.9 0.0 4.5e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.23 OAJ14376.1 - 3.7e-12 46.3 0.0 9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ14376.1 - 0.002 18.5 2.0 0.044 14.2 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ14376.1 - 0.0052 16.7 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAJ14376.1 - 0.015 15.8 0.1 0.042 14.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OAJ14376.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OAJ14376.1 - 0.064 13.5 0.1 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Gluconate_2-dh3 PF13618.6 OAJ14376.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 AAA_29 PF13555.6 OAJ14376.1 - 0.18 11.5 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sec23_trunk PF04811.15 OAJ14377.1 - 2.2e-76 256.6 0.0 3.2e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAJ14377.1 - 4.4e-31 107.5 0.0 7.9e-31 106.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAJ14377.1 - 6.6e-26 90.1 0.2 1.3e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAJ14377.1 - 7.3e-16 57.9 6.2 1.4e-15 57.1 6.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ14377.1 - 3.5e-13 49.3 0.0 7.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAJ14377.1 - 0.13 11.7 0.1 0.27 10.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RF-1 PF00472.20 OAJ14378.1 - 4.8e-18 65.2 0.5 6.5e-18 64.8 0.5 1.1 1 0 0 1 1 1 1 RF-1 domain tRNA_int_endo PF01974.17 OAJ14379.1 - 8e-18 64.3 0.0 1.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Polysacc_deac_1 PF01522.21 OAJ14380.1 - 0.019 14.9 0.3 0.1 12.5 0.3 2.3 1 1 0 1 1 1 0 Polysaccharide deacetylase Arylesterase PF01731.20 OAJ14382.1 - 0.0035 17.5 0.0 0.0066 16.6 0.0 1.4 1 0 0 1 1 1 1 Arylesterase BolA PF01722.18 OAJ14392.1 - 8e-31 106.1 0.3 9.8e-31 105.9 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein HATPase_c PF02518.26 OAJ14393.1 - 1.5e-18 67.3 0.3 4.8e-18 65.7 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ14393.1 - 1e-17 64.3 0.0 1.6e-10 41.1 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 OAJ14393.1 - 1.7e-16 60.0 0.1 4.2e-16 58.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Antibiotic_NAT PF02522.14 OAJ14393.1 - 0.13 12.1 1.9 0.33 10.7 1.9 1.6 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Opi1 PF08618.10 OAJ14394.1 - 1.4e-62 212.3 5.2 1.4e-62 212.3 5.2 3.8 3 2 2 5 5 5 1 Transcription factor Opi1 SbcCD_C PF13558.6 OAJ14394.1 - 9.6 6.5 5.8 2.6 8.3 0.3 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CNH PF00780.22 OAJ14395.1 - 1.2e-80 271.1 0.0 2.1e-80 270.3 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 OAJ14395.1 - 1.2e-44 151.7 0.0 3.1e-44 150.4 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAJ14395.1 - 2.4e-37 128.9 1.1 4.5e-37 128.1 1.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ14395.1 - 1.6e-13 50.5 0.0 3.7e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 OAJ14395.1 - 0.00089 19.1 0.2 0.0063 16.3 0.1 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 OAJ14395.1 - 0.18 11.6 0.4 5.4 6.9 0.0 2.5 2 0 0 2 2 2 0 PH domain IlvN PF07991.12 OAJ14396.1 - 1e-46 158.5 0.0 2.5e-46 157.3 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAJ14396.1 - 2e-39 135.1 0.0 3.2e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 OAJ14396.1 - 0.069 13.7 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.19 OAJ14396.1 - 0.099 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase BATS PF06968.13 OAJ14397.1 - 3.4e-19 68.8 1.2 8.5e-19 67.5 0.0 2.3 3 0 0 3 3 3 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAJ14397.1 - 1.4e-12 48.3 0.1 2.4e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Na_H_Exchanger PF00999.21 OAJ14398.1 - 3e-55 187.6 48.5 4.8e-55 186.9 48.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_4 PF02390.17 OAJ14399.1 - 4.2e-53 179.3 0.0 1.2e-39 135.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 OAJ14399.1 - 0.042 14.6 0.0 0.45 11.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ14399.1 - 0.089 13.5 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 OAJ14399.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PAP2 PF01569.21 OAJ14411.1 - 0.076 12.8 0.9 0.12 12.1 0.9 1.4 1 0 0 1 1 1 0 PAP2 superfamily SOBP PF15279.6 OAJ14411.1 - 0.16 12.5 4.2 0.2 12.2 4.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Retinal PF15449.6 OAJ14411.1 - 1.5 6.5 8.7 1.7 6.3 8.7 1.0 1 0 0 1 1 1 0 Retinal protein Sporozoite_P67 PF05642.11 OAJ14411.1 - 4.8 5.1 4.8 5.8 4.9 4.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF282 PF03380.14 OAJ14413.1 - 0.023 14.6 1.3 0.098 12.6 0.3 2.5 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Coiled-coil_56 PF09813.9 OAJ14414.1 - 0.0012 18.9 0.1 0.0027 17.7 0.0 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 Apolipoprotein PF01442.18 OAJ14414.1 - 0.032 14.1 1.0 0.043 13.7 1.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.6 OAJ14414.1 - 0.13 11.8 0.8 0.16 11.5 0.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Inv-AAD PF18785.1 OAJ14415.1 - 2e-25 89.1 0.1 3.4e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAJ14415.1 - 5.8e-12 45.4 0.5 9.6e-12 44.7 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAJ14415.1 - 1.3e-09 38.2 0.2 1.8e-09 37.8 0.2 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 OAJ14415.1 - 1.2e-05 25.4 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 SNAD4 PF18750.1 OAJ14415.1 - 5.2e-05 23.3 0.0 8.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 OAJ14415.1 - 0.00021 21.4 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 OAJ14415.1 - 0.0047 17.1 0.0 0.0063 16.6 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 OAJ14415.1 - 0.0062 16.6 0.1 0.0083 16.2 0.1 1.3 1 0 0 1 1 1 1 APOBEC2 ThiF PF00899.21 OAJ14416.1 - 2.5e-62 210.4 0.0 3.7e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OAJ14416.1 - 7e-08 33.0 0.0 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.6 OAJ14416.1 - 1.4e-05 25.5 0.1 2.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAJ14416.1 - 4e-05 23.7 0.1 0.00015 21.8 0.0 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAJ14416.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAJ14416.1 - 0.081 13.2 1.0 0.53 10.5 1.0 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 OAJ14416.1 - 0.11 12.1 0.4 0.17 11.4 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 OAJ14416.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GCV_H PF01597.19 OAJ14416.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein AAA_5 PF07728.14 OAJ14417.1 - 4.2e-114 376.6 0.0 3.5e-20 72.4 0.0 10.3 9 1 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAJ14417.1 - 2.6e-45 153.0 3.1 3.3e-16 59.4 0.0 4.6 3 0 0 3 3 3 3 Midasin AAA lid domain AAA_7 PF12775.7 OAJ14417.1 - 1.7e-27 96.1 1.8 1e-06 28.4 0.0 6.6 6 0 0 6 6 6 4 P-loop containing dynein motor region AAA PF00004.29 OAJ14417.1 - 4.7e-27 95.0 0.0 0.0056 17.1 0.0 7.8 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OAJ14417.1 - 1.4e-25 89.7 0.0 7.5e-08 32.3 0.0 7.6 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 OAJ14417.1 - 1.7e-22 79.5 0.0 8.4e-22 77.3 0.0 2.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_22 PF13401.6 OAJ14417.1 - 1.2e-21 77.4 1.7 0.0012 19.1 0.0 8.0 7 0 0 7 7 7 3 AAA domain AAA_16 PF13191.6 OAJ14417.1 - 2.2e-17 63.9 55.3 8.6e-05 23.0 0.3 12.2 11 4 0 11 11 8 6 AAA ATPase domain AAA_6 PF12774.7 OAJ14417.1 - 6.3e-17 61.5 0.2 0.013 14.5 0.1 7.1 7 0 0 7 7 6 3 Hydrolytic ATP binding site of dynein motor region ABC_tran PF00005.27 OAJ14417.1 - 7.1e-17 62.2 1.2 0.0066 17.0 0.0 7.1 7 0 0 7 7 5 3 ABC transporter Dynein_heavy PF03028.15 OAJ14417.1 - 8.3e-17 61.4 0.0 0.025 14.7 0.0 7.2 7 0 0 7 7 6 3 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 OAJ14417.1 - 3.2e-15 56.8 0.4 0.38 11.3 0.0 7.3 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 OAJ14417.1 - 4.8e-15 55.8 6.3 0.073 12.8 0.2 8.3 7 1 0 7 7 7 4 AAA domain Sigma54_activat PF00158.26 OAJ14417.1 - 1.4e-14 54.1 0.0 0.0064 16.2 0.0 5.8 6 0 0 6 6 6 3 Sigma-54 interaction domain TsaE PF02367.17 OAJ14417.1 - 3e-14 53.1 5.5 0.07 13.1 0.1 7.1 7 0 0 7 7 7 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ14417.1 - 2.5e-13 50.4 1.3 0.033 14.3 0.1 7.2 6 0 0 6 6 6 2 AAA domain NACHT PF05729.12 OAJ14417.1 - 5.4e-12 45.9 2.5 0.013 15.5 0.0 6.3 5 0 0 5 5 5 3 NACHT domain AAA_19 PF13245.6 OAJ14417.1 - 2.2e-11 44.3 8.8 0.15 12.4 0.0 6.9 6 1 0 6 6 5 2 AAA domain AAA_14 PF13173.6 OAJ14417.1 - 3.4e-11 43.3 0.0 0.042 13.9 0.0 6.7 8 0 0 8 8 5 2 AAA domain RNA_helicase PF00910.22 OAJ14417.1 - 7.5e-10 39.2 0.7 1.8 9.0 0.0 6.7 6 0 0 6 6 6 1 RNA helicase AAA_29 PF13555.6 OAJ14417.1 - 9e-10 38.1 0.6 0.57 10.0 0.0 5.9 6 0 0 6 6 5 1 P-loop containing region of AAA domain AAA_28 PF13521.6 OAJ14417.1 - 1.2e-09 38.7 7.9 2.2 8.5 0.1 7.1 6 0 0 6 6 6 1 AAA domain Zeta_toxin PF06414.12 OAJ14417.1 - 2.1e-09 37.0 1.4 0.17 11.2 0.0 6.7 6 0 0 6 6 6 1 Zeta toxin Mg_chelatase PF01078.21 OAJ14417.1 - 3e-09 36.6 4.9 0.24 10.8 0.1 7.6 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 OAJ14417.1 - 8.7e-09 35.5 4.5 0.078 12.9 0.0 5.6 6 0 0 6 6 5 2 RsgA GTPase T2SSE PF00437.20 OAJ14417.1 - 1e-08 34.6 9.1 0.12 11.4 0.0 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 OAJ14417.1 - 1.3e-08 35.1 0.6 0.41 10.7 0.0 6.3 6 0 0 6 6 6 2 Sigma-54 interaction domain DUF815 PF05673.13 OAJ14417.1 - 1.6e-08 34.0 1.3 0.33 10.1 0.0 5.6 5 0 0 5 5 5 1 Protein of unknown function (DUF815) Rad17 PF03215.15 OAJ14417.1 - 2e-07 31.1 0.7 0.17 11.8 0.0 5.8 6 0 0 6 6 5 1 Rad17 P-loop domain IstB_IS21 PF01695.17 OAJ14417.1 - 2.1e-07 30.9 2.6 0.43 10.3 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein TniB PF05621.11 OAJ14417.1 - 2.4e-07 30.4 0.0 0.57 9.6 0.0 5.5 6 0 0 6 6 5 1 Bacterial TniB protein Roc PF08477.13 OAJ14417.1 - 5.1e-07 29.9 2.2 3.5 7.9 0.0 6.0 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ14417.1 - 8.6e-07 28.9 0.5 2.4 7.8 0.0 6.1 6 0 0 6 6 6 1 AAA domain AAA_25 PF13481.6 OAJ14417.1 - 2.9e-06 27.0 17.5 1.8 8.1 0.1 7.3 7 0 0 7 7 6 2 AAA domain PduV-EutP PF10662.9 OAJ14417.1 - 5.2e-06 26.3 3.7 0.37 10.5 0.0 5.3 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 OAJ14417.1 - 6.1e-05 23.0 0.1 13 5.4 0.0 4.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system ATPase PF06745.13 OAJ14417.1 - 7.1e-05 22.3 1.2 8 5.7 0.0 4.9 5 0 0 5 5 5 0 KaiC RuvB_N PF05496.12 OAJ14417.1 - 9.9e-05 22.1 2.4 26 4.5 0.1 6.0 6 0 0 6 6 6 0 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 OAJ14417.1 - 0.00016 21.7 0.6 34 4.6 0.0 5.9 6 0 0 6 6 5 0 50S ribosome-binding GTPase ResIII PF04851.15 OAJ14417.1 - 0.00029 20.9 2.6 3.8 7.5 0.1 4.8 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 OAJ14417.1 - 0.0003 20.5 5.6 0.69 9.5 0.0 5.1 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain CPT PF07931.12 OAJ14417.1 - 0.00047 20.1 6.6 1.5 8.6 0.0 7.6 9 1 0 9 9 7 1 Chloramphenicol phosphotransferase-like protein AAA_8 PF12780.7 OAJ14417.1 - 0.00051 19.4 0.1 14 4.9 0.0 4.7 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 Viral_helicase1 PF01443.18 OAJ14417.1 - 0.00055 19.7 1.0 9.1 5.9 0.0 5.8 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 OAJ14417.1 - 0.001 18.1 1.0 2.6 7.0 0.0 3.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 OAJ14417.1 - 0.0022 17.6 10.0 6.1 6.4 0.1 5.6 6 1 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 OAJ14417.1 - 0.0042 16.9 1.9 12 5.6 0.1 4.5 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 OAJ14417.1 - 0.0053 16.7 0.0 12 5.7 0.0 4.5 5 0 0 5 5 4 0 ATPase domain predominantly from Archaea PhoH PF02562.16 OAJ14417.1 - 0.0065 15.9 3.9 2.9 7.3 0.1 4.0 4 0 0 4 4 4 0 PhoH-like protein TIP49 PF06068.13 OAJ14417.1 - 0.0072 15.6 6.1 2.8 7.1 0.0 4.5 5 0 0 5 5 5 1 TIP49 P-loop domain DnaB_C PF03796.15 OAJ14417.1 - 0.0091 15.4 4.6 2.4 7.4 0.2 4.7 5 0 0 5 5 5 1 DnaB-like helicase C terminal domain dNK PF01712.19 OAJ14417.1 - 0.017 15.0 2.3 25 4.7 0.0 4.4 5 0 0 5 5 4 0 Deoxynucleoside kinase SRPRB PF09439.10 OAJ14417.1 - 0.019 14.4 5.2 60 3.0 0.0 6.4 8 0 0 8 8 7 0 Signal recognition particle receptor beta subunit PSY3 PF16836.5 OAJ14417.1 - 0.023 14.2 0.2 0.098 12.2 0.2 2.1 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description MCM PF00493.23 OAJ14417.1 - 0.026 13.6 0.0 17 4.4 0.0 4.0 4 0 0 4 4 4 0 MCM P-loop domain NTPase_1 PF03266.15 OAJ14417.1 - 0.044 13.7 7.1 5.4 6.9 0.0 5.3 6 0 0 6 6 5 0 NTPase AAA_23 PF13476.6 OAJ14417.1 - 0.045 14.2 0.0 0.045 14.2 0.0 8.2 9 2 0 9 9 6 0 AAA domain AAA_15 PF13175.6 OAJ14417.1 - 0.056 13.1 1.8 28 4.3 0.0 4.3 5 0 0 5 5 3 0 AAA ATPase domain vWA-TerF-like PF10138.9 OAJ14417.1 - 0.057 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 vWA found in TerF C terminus Bac_DnaA PF00308.18 OAJ14417.1 - 0.063 13.1 0.1 10 5.9 0.0 3.2 3 0 0 3 3 2 0 Bacterial dnaA protein FtsK_SpoIIIE PF01580.18 OAJ14417.1 - 0.081 12.3 2.9 6 6.1 0.1 4.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family IPT PF01745.16 OAJ14417.1 - 0.12 11.8 1.5 16 4.8 0.0 3.9 4 0 0 4 4 4 0 Isopentenyl transferase Ploopntkinase3 PF18751.1 OAJ14417.1 - 0.12 12.3 0.7 59 3.5 0.0 4.1 5 0 0 5 5 3 0 P-loop Nucleotide Kinase3 MobB PF03205.14 OAJ14417.1 - 0.48 10.3 2.3 10 6.0 0.1 3.9 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B Ras PF00071.22 OAJ14418.1 - 3.5e-34 117.7 0.3 4.4e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ14418.1 - 2.1e-26 92.5 0.1 4.1e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ14418.1 - 8.9e-08 31.8 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ14418.1 - 4.1e-07 29.6 0.3 5.6e-07 29.1 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 OAJ14418.1 - 0.0022 16.9 0.5 0.17 10.7 0.0 2.4 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 OAJ14418.1 - 0.013 14.6 2.9 0.1 11.7 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit MID_MedPIWI PF18296.1 OAJ14418.1 - 0.029 14.2 0.4 0.051 13.4 0.4 1.4 1 0 0 1 1 1 0 MID domain of medPIWI MMR_HSR1 PF01926.23 OAJ14418.1 - 0.048 13.7 0.0 0.081 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ14418.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OAJ14418.1 - 0.088 12.2 0.0 2.2 7.7 0.0 2.4 2 1 0 2 2 2 0 Bacterial TniB protein Utp21 PF04192.12 OAJ14419.1 - 3.6e-51 173.9 0.0 6.3e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAJ14419.1 - 8.5e-16 58.0 0.0 0.0012 19.1 0.0 7.4 5 2 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ14419.1 - 6.4e-11 42.6 8.5 0.017 16.0 0.1 7.7 8 0 0 8 8 8 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAJ14419.1 - 0.006 16.6 0.0 0.25 11.4 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OAJ14419.1 - 0.076 12.0 0.1 4.6 6.1 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ14419.1 - 0.099 12.6 0.3 0.35 10.9 0.3 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Utp8 PF10395.9 OAJ14419.1 - 0.29 9.6 0.0 0.48 8.9 0.0 1.2 1 0 0 1 1 1 0 Utp8 family TFIIA PF03153.13 OAJ14419.1 - 4.5 7.2 6.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BolA PF01722.18 OAJ14420.1 - 5.4e-16 58.6 0.1 9.5e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 OAJ14421.1 - 7.1e-91 304.9 0.0 1e-90 304.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ14421.1 - 0.00047 21.1 0.0 0.0017 19.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain eIF3m_C_helix PF18005.1 OAJ14427.1 - 7.5e-08 31.9 1.1 7.5e-08 31.9 1.1 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 OAJ14427.1 - 0.0052 17.3 0.0 0.018 15.5 0.0 2.0 1 0 0 1 1 1 1 PCI domain ubiquitin PF00240.23 OAJ14428.1 - 2.9e-21 75.0 0.1 4.4e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAJ14428.1 - 1.3e-12 47.3 3.3 5.8e-08 32.5 0.4 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 OAJ14428.1 - 1.9e-12 46.7 12.6 3.7e-12 45.8 12.6 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 OAJ14428.1 - 4.1e-06 26.5 0.1 6.5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAJ14428.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 OAJ14428.1 - 0.028 14.3 0.0 0.4 10.5 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain ZapB PF06005.12 OAJ14428.1 - 0.084 13.3 0.7 31 5.1 0.5 3.0 3 0 0 3 3 3 0 Cell division protein ZapB MCM_N PF14551.6 OAJ14428.1 - 0.14 12.7 0.1 0.45 11.1 0.0 1.8 2 0 0 2 2 2 0 MCM N-terminal domain CSTF2_hinge PF14327.6 OAJ14428.1 - 0.24 11.9 5.0 3.4 8.2 5.3 2.3 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RuBisCO_large_N PF02788.16 OAJ14428.1 - 0.48 10.6 2.1 1 9.5 2.1 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain F-box PF00646.33 OAJ14429.1 - 5.1e-08 32.6 1.1 8.8e-08 31.8 1.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ14429.1 - 0.006 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 OAJ14430.1 - 4.6e-72 242.6 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14430.1 - 6.2e-31 107.6 0.0 9.5e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14430.1 - 5e-06 26.1 0.7 0.02 14.2 0.2 2.3 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 OAJ14430.1 - 0.0016 18.1 0.2 0.0026 17.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ14430.1 - 0.027 14.4 1.7 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ14430.1 - 0.043 12.8 0.1 0.062 12.2 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAJ14430.1 - 0.1 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SEEEED PF14797.6 OAJ14430.1 - 2.3 8.4 7.0 3.2 7.9 7.0 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex TPR_10 PF13374.6 OAJ14431.1 - 0.0001 22.0 10.1 0.35 10.8 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ14431.1 - 0.00049 20.5 9.8 0.36 11.6 0.5 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ14431.1 - 0.0068 15.8 3.5 1.7 7.9 0.3 3.1 2 2 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 OAJ14431.1 - 0.024 14.5 1.6 37 4.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 OAJ14431.1 - 0.081 12.3 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_8 PF13181.6 OAJ14431.1 - 0.083 13.2 3.1 59 4.3 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14431.1 - 0.2 11.9 11.1 22 5.5 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14431.1 - 0.3 11.4 9.5 13 6.2 0.6 5.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ14431.1 - 1.1 10.0 8.4 11 6.8 0.1 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 OAJ14432.1 - 0.034 14.0 0.2 0.088 12.7 0.2 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAJ14432.1 - 0.042 13.7 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like PS_Dcarbxylase PF02666.15 OAJ14433.1 - 2.5e-51 174.1 0.0 4.1e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAJ14433.1 - 8.1e-31 106.4 0.0 6.8e-17 61.7 0.0 4.1 3 1 0 3 3 3 3 C2 domain EF-hand_6 PF13405.6 OAJ14433.1 - 0.00081 19.1 0.2 0.0023 17.7 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain Tub_N PF16322.5 OAJ14433.1 - 0.0051 17.3 3.4 0.0051 17.3 3.4 3.0 3 0 0 3 3 3 1 Tubby N-terminal PPP4R2 PF09184.11 OAJ14433.1 - 0.16 11.5 10.5 0.34 10.4 10.5 1.5 1 0 0 1 1 1 0 PPP4R2 DUF4637 PF15470.6 OAJ14433.1 - 0.41 10.3 9.5 1.2 8.9 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Nop14 PF04147.12 OAJ14433.1 - 0.49 8.5 20.2 0.84 7.8 20.2 1.3 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 OAJ14433.1 - 2.1 7.7 17.1 4.3 6.6 17.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.11 OAJ14434.1 - 1.9e-05 24.7 13.3 1.9e-05 24.7 13.3 4.0 3 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) SNAPc_SNAP43 PF09808.9 OAJ14434.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 SPESP1 PF15754.5 OAJ14434.1 - 0.34 10.0 3.9 0.65 9.1 3.9 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 F-box PF00646.33 OAJ14435.1 - 4.3e-09 36.0 0.1 9.7e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ14435.1 - 0.00093 19.0 0.1 0.0018 18.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ14435.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 F-box MaoC_dehydratas PF01575.19 OAJ14436.1 - 0.077 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain PNP_UDP_1 PF01048.20 OAJ14437.1 - 3.2e-35 121.5 0.4 3.8e-35 121.2 0.4 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Tho1_MOS11_C PF18592.1 OAJ14438.1 - 2.5e-07 30.4 16.2 3.7e-05 23.4 1.5 3.0 2 2 0 2 2 2 2 Tho1/MOS11 C-terminal domain NAM-associated PF14303.6 OAJ14438.1 - 0.00018 22.2 0.4 0.0017 19.1 0.4 2.5 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Apt1 PF10351.9 OAJ14438.1 - 4.5 6.0 5.8 2 7.2 1.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Glyco_transf_4 PF13439.6 OAJ14439.1 - 0.11 12.5 0.3 0.17 11.9 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pkinase PF00069.25 OAJ14440.1 - 2e-58 197.8 0.0 1.5e-34 119.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14440.1 - 1.7e-33 116.0 0.0 2.7e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ14440.1 - 0.00013 22.0 0.1 0.00013 22.0 0.1 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ14440.1 - 0.0059 16.0 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4207 PF13904.6 OAJ14440.1 - 4 7.1 12.9 11 5.6 12.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CbiN PF02553.15 OAJ14441.1 - 0.22 11.5 1.9 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Cobalt transport protein component CbiN Ferric_reduct PF01794.19 OAJ14441.1 - 0.34 11.0 8.3 0.37 10.9 5.0 2.2 2 0 0 2 2 2 0 Ferric reductase like transmembrane component TraK PF06586.11 OAJ14442.1 - 0.0056 16.4 0.9 0.091 12.4 0.0 2.3 1 1 1 2 2 2 2 TraK protein FAT PF02259.23 OAJ14452.1 - 4.8e-80 269.4 0.3 6.8e-80 268.9 0.3 1.2 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ14452.1 - 2.7e-65 220.7 0.0 4e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 OAJ14452.1 - 1.8e-40 137.3 0.5 1.8e-40 137.3 0.5 2.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 OAJ14452.1 - 5e-10 39.0 0.3 1.6e-09 37.4 0.3 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 OAJ14452.1 - 0.082 13.4 0.2 26 5.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PEN-2 PF10251.9 OAJ14454.1 - 0.0054 17.1 0.8 0.012 16.0 0.8 1.5 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase zf-NOSIP PF15906.5 OAJ14456.1 - 1.3e-12 47.7 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 OAJ14456.1 - 7.7e-06 25.8 14.2 8.6e-05 22.4 3.1 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ14456.1 - 1.5e-05 24.9 15.6 0.00067 19.6 3.7 3.0 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ14456.1 - 2.7e-05 23.9 17.0 0.00063 19.5 5.5 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ14456.1 - 7.9e-05 22.9 17.4 0.011 16.0 4.7 3.0 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ14456.1 - 9.3e-05 22.2 18.8 0.0012 18.7 4.7 3.4 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 OAJ14456.1 - 0.00014 21.4 11.0 0.00081 18.8 2.4 3.2 2 1 1 3 3 3 2 Rtf2 RING-finger FYVE PF01363.21 OAJ14456.1 - 0.0018 18.3 4.7 0.0018 18.3 4.7 2.8 2 2 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.6 OAJ14456.1 - 0.012 15.7 19.2 0.012 15.7 4.5 4.0 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ14456.1 - 0.065 13.1 22.3 1.1 9.1 6.4 4.2 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAJ14456.1 - 0.066 13.1 19.3 0.081 12.8 5.4 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 OAJ14456.1 - 0.14 12.3 2.6 14 5.9 0.1 3.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 OAJ14456.1 - 2.6 7.6 13.7 0.59 9.6 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon domain Transformer PF06495.11 OAJ14456.1 - 5.3 7.1 7.8 10 6.1 7.8 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein ABC_membrane PF00664.23 OAJ14457.1 - 8e-83 278.2 22.0 3.5e-42 145.0 11.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ14457.1 - 1.3e-60 203.9 0.0 3.5e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ14457.1 - 3.5e-10 39.7 3.5 0.00066 19.2 0.1 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ14457.1 - 1.1e-06 29.1 4.7 0.00034 21.1 0.1 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ14457.1 - 1.3e-06 28.0 2.3 0.027 14.2 0.7 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ14457.1 - 1.5e-06 28.3 4.4 0.02 14.7 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 OAJ14457.1 - 2e-06 27.5 0.9 0.12 12.0 0.0 4.0 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ14457.1 - 1.7e-05 24.8 0.2 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 OAJ14457.1 - 5.2e-05 23.0 0.2 1.2 8.9 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.6 OAJ14457.1 - 0.00042 20.8 0.0 0.3 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ14457.1 - 0.0006 20.1 4.6 0.21 11.9 0.7 3.9 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 OAJ14457.1 - 0.001 18.4 0.2 0.11 11.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OAJ14457.1 - 0.0059 16.3 1.3 4.4 7.0 0.1 3.4 2 2 0 2 2 2 1 AAA domain ATPase PF06745.13 OAJ14457.1 - 0.0061 15.9 0.4 3.3 7.0 0.2 2.6 2 0 0 2 2 2 1 KaiC TniB PF05621.11 OAJ14457.1 - 0.0088 15.5 0.3 11 5.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 OAJ14457.1 - 0.0094 16.1 2.6 1.5 9.0 0.0 3.7 3 1 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 OAJ14457.1 - 0.0096 14.8 1.4 0.12 11.1 0.0 3.0 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 OAJ14457.1 - 0.013 15.5 0.6 5.2 7.1 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 OAJ14457.1 - 0.013 15.2 0.1 6.2 6.4 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 OAJ14457.1 - 0.016 14.8 0.0 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 OAJ14457.1 - 0.024 14.4 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 OAJ14457.1 - 0.024 14.9 3.1 0.38 11.0 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 OAJ14457.1 - 0.029 14.9 3.1 8.3 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ14457.1 - 0.032 14.6 0.2 2.3 8.6 0.1 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ14457.1 - 0.034 14.0 0.9 1.2 9.0 0.0 3.1 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 OAJ14457.1 - 0.038 13.2 0.1 0.89 8.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF3987 PF13148.6 OAJ14457.1 - 0.048 12.7 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 OAJ14457.1 - 0.052 13.6 0.7 1 9.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 OAJ14457.1 - 0.061 13.2 0.2 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 OAJ14457.1 - 0.064 13.0 0.1 0.84 9.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 OAJ14457.1 - 0.077 12.4 0.1 5.2 6.4 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 OAJ14457.1 - 0.1 11.8 0.4 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OAJ14457.1 - 0.11 12.3 0.8 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ14457.1 - 0.15 11.6 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 OAJ14457.1 - 0.15 12.1 5.4 0.99 9.4 0.2 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain COX4 PF02936.14 OAJ14457.1 - 0.18 11.8 1.1 33 4.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Dynactin_p62 PF05502.13 OAJ14458.1 - 9.6e-35 120.3 1.2 7.5e-22 77.7 0.2 3.0 3 0 0 3 3 3 3 Dynactin p62 family FAT PF02259.23 OAJ14459.1 - 3.7e-109 365.1 3.5 3.7e-109 365.1 3.5 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ14459.1 - 2.8e-64 217.3 0.1 5e-64 216.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 OAJ14459.1 - 1.6e-51 174.4 0.0 1.7e-45 154.9 0.0 4.4 3 1 1 4 4 4 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 OAJ14459.1 - 5.6e-27 94.1 0.1 5.6e-27 94.1 0.1 2.9 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 OAJ14459.1 - 6e-15 55.4 19.6 0.00096 19.5 0.3 10.7 8 3 3 11 11 10 3 HEAT repeats HEAT PF02985.22 OAJ14459.1 - 3.7e-09 36.1 25.9 0.39 11.1 0.0 12.1 13 0 0 13 13 11 4 HEAT repeat FATC PF02260.20 OAJ14459.1 - 1.6e-08 34.2 0.1 4.2e-08 32.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain UME PF08064.13 OAJ14459.1 - 2e-08 34.1 0.3 0.056 13.4 0.0 6.2 4 1 2 6 6 6 1 UME (NUC010) domain HEAT_EZ PF13513.6 OAJ14459.1 - 8.9e-07 29.3 35.0 0.18 12.3 0.2 11.1 12 2 1 13 13 11 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ14459.1 - 1.7e-05 25.3 0.0 12 6.6 0.0 6.5 5 2 2 7 7 7 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ14459.1 - 0.00011 22.3 0.2 0.86 9.6 0.0 4.5 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ14459.1 - 0.02 13.5 1.3 1.3 7.5 0.2 3.9 4 1 0 4 4 4 0 Adaptin N terminal region RTP1_C1 PF10363.9 OAJ14459.1 - 0.051 13.8 2.1 6.5 7.0 0.0 4.7 5 1 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 OAJ14459.1 - 0.058 12.9 2.1 0.66 9.5 0.0 3.1 3 0 0 3 3 3 0 Tti2 family TPR_19 PF14559.6 OAJ14459.1 - 0.062 13.8 6.6 13 6.4 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat IBN_N PF03810.19 OAJ14459.1 - 0.074 13.0 0.1 3 7.8 0.0 3.5 3 0 0 3 3 3 0 Importin-beta N-terminal domain VHS PF00790.19 OAJ14459.1 - 0.086 12.7 0.0 3.7 7.4 0.0 3.5 3 1 1 4 4 4 0 VHS domain DUF3535 PF12054.8 OAJ14459.1 - 0.091 12.0 0.1 11 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) TFIID-18kDa PF02269.16 OAJ14459.1 - 0.13 12.3 0.0 0.65 10.1 0.0 2.2 2 0 0 2 2 1 0 Transcription initiation factor IID, 18kD subunit RICTOR_N PF14664.6 OAJ14459.1 - 0.29 10.1 2.6 9.1 5.2 0.1 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term ANAPC3 PF12895.7 OAJ14459.1 - 1.1 9.5 8.3 63 3.9 0.3 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ACPS PF01648.20 OAJ14460.1 - 1.7e-07 31.4 0.1 3e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily zf-met2 PF12907.7 OAJ14462.1 - 6.5e-12 45.4 3.6 1e-11 44.7 3.6 1.4 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAJ14462.1 - 2.8e-08 34.5 13.3 4.8e-08 33.7 13.3 1.4 1 0 0 1 1 1 1 4F5 protein family zf-C2H2_4 PF13894.6 OAJ14462.1 - 0.015 16.1 0.4 0.053 14.4 0.4 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Eapp_C PF10238.9 OAJ14462.1 - 0.018 15.1 0.9 0.021 14.9 0.9 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein TPT PF03151.16 OAJ14463.1 - 3.3e-25 89.0 15.6 4e-25 88.8 15.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family IMS PF00817.20 OAJ14464.1 - 1.4e-35 122.5 0.0 3.1e-35 121.4 0.0 1.6 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ14464.1 - 1.8e-06 28.6 0.0 4.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ14464.1 - 0.039 14.3 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif zf_UBZ PF18439.1 OAJ14464.1 - 0.11 12.1 4.9 2.5 7.8 1.7 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Methyltransf_28 PF02636.17 OAJ14478.1 - 3.4e-65 220.3 0.0 5.1e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DARPP-32 PF05395.12 OAJ14478.1 - 0.082 13.1 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 SGS PF05002.15 OAJ14479.1 - 5.7e-29 100.1 1.3 1e-28 99.2 1.3 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OAJ14479.1 - 1.1e-13 52.0 0.0 1.7e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 CS domain Uds1 PF15456.6 OAJ14480.1 - 6.2e-23 81.4 3.6 6.2e-23 81.4 3.6 13.8 4 2 5 10 10 10 2 Up-regulated During Septation Collagen PF01391.18 OAJ14481.1 - 3.9e-24 84.2 178.3 2.3e-08 33.6 32.0 4.9 3 1 2 5 5 5 4 Collagen triple helix repeat (20 copies) Peptidase_S8 PF00082.22 OAJ14483.1 - 3.2e-39 135.0 4.3 4.6e-39 134.5 4.3 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ14483.1 - 1.7e-10 41.6 0.4 3.8e-10 40.5 0.4 1.6 1 0 0 1 1 1 1 Fn3-like domain Dcc1 PF09724.9 OAJ14484.1 - 7.1e-68 229.3 0.0 1.3e-67 228.5 0.0 1.4 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Pkinase PF00069.25 OAJ14487.1 - 3.9e-71 239.5 0.0 4.9e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14487.1 - 4.3e-31 108.1 0.0 5.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ14487.1 - 2e-13 50.8 0.9 2e-13 50.8 0.9 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAJ14487.1 - 8.6e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ14487.1 - 0.00055 19.3 0.0 0.002 17.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ14487.1 - 0.024 14.3 0.0 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAJ14487.1 - 0.03 13.7 0.1 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ14487.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SR-25 PF10500.9 OAJ14487.1 - 2.1 7.9 6.3 4 7.0 6.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phage_holin_3_6 PF07332.11 OAJ14489.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_S6 PF01250.17 OAJ14504.1 - 1.5e-23 82.9 0.0 1.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 UQ_con PF00179.26 OAJ14505.1 - 1.7e-17 63.4 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ14505.1 - 0.019 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain CLTH PF10607.9 OAJ14506.1 - 1.3e-16 60.8 0.0 4.2e-16 59.2 0.0 1.8 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4658 PF15555.6 OAJ14506.1 - 0.058 13.5 1.3 0.22 11.6 1.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) LisH PF08513.11 OAJ14506.1 - 0.16 12.0 0.2 0.42 10.7 0.2 1.6 1 0 0 1 1 1 0 LisH Macoilin PF09726.9 OAJ14506.1 - 0.21 10.1 15.4 0.34 9.4 15.4 1.3 1 0 0 1 1 1 0 Macoilin family ATF7IP_BD PF16788.5 OAJ14506.1 - 1.6 8.8 12.2 4.4 7.4 12.2 1.8 1 0 0 1 1 1 0 ATF-interacting protein binding domain DUF5542 PF17696.1 OAJ14506.1 - 3.6 7.8 7.0 46 4.2 4.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5542) FA_hydroxylase PF04116.13 OAJ14509.1 - 7.6e-20 71.6 17.1 7.6e-20 71.6 17.1 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily 2TM PF13239.6 OAJ14509.1 - 0.13 12.6 3.5 8 6.8 0.0 2.3 2 0 0 2 2 2 0 2TM domain CHORD PF04968.12 OAJ14510.1 - 3.9e-41 139.6 20.2 7.7e-22 77.8 7.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAJ14510.1 - 1.4e-08 35.6 0.0 2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OAJ14510.1 - 0.058 13.2 1.4 0.64 9.9 0.2 2.6 2 0 0 2 2 2 0 BTK motif Lipase_GDSL_2 PF13472.6 OAJ14511.1 - 2.3e-22 80.2 0.0 2.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAJ14511.1 - 6.3e-15 55.7 0.0 9.8e-15 55.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TEA PF01285.18 OAJ14512.1 - 2.2e-28 98.1 0.0 4.3e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain RPS31 PF17067.5 OAJ14512.1 - 4.8 7.4 8.9 0.51 10.5 0.5 3.3 2 0 0 2 2 2 0 Ribosomal protein S31e DUF2013 PF09431.10 OAJ14513.1 - 1.3e-54 184.1 1.4 2.2e-54 183.4 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) RRM_1 PF00076.22 OAJ14514.1 - 9.9e-35 118.2 0.1 9.8e-20 70.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAJ14514.1 - 5e-11 43.5 2.6 9.9e-10 39.4 2.6 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAJ14514.1 - 2.7e-06 27.2 0.0 0.032 14.1 0.0 2.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAJ14514.1 - 0.0005 19.7 0.0 0.35 10.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ14514.1 - 0.0014 18.7 0.0 0.0084 16.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ14514.1 - 0.012 15.6 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ANAPC4_WD40 PF12894.7 OAJ14515.1 - 3.1e-10 40.2 0.0 0.00044 20.5 0.0 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ14515.1 - 0.00024 21.8 6.1 0.027 15.3 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 OAJ14515.1 - 0.0004 20.2 0.1 0.44 10.5 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OAJ14515.1 - 0.0065 16.4 0.0 3.2 7.6 0.0 3.6 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A His_Phos_1 PF00300.22 OAJ14516.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Helicase_C PF00271.31 OAJ14517.1 - 6e-11 42.7 0.0 1.7e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ14517.1 - 2.3e-09 37.2 0.0 6.8e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4638 PF15472.6 OAJ14529.1 - 0.098 12.4 1.1 0.15 11.7 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) LIM PF00412.22 OAJ14530.1 - 1.2e-29 102.3 33.6 1.1e-13 51.2 6.2 5.7 6 0 0 6 6 6 4 LIM domain POB3_N PF17292.2 OAJ14531.1 - 5.3e-23 81.3 0.0 1.1e-20 73.9 0.0 2.5 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 OAJ14531.1 - 6.6e-21 74.5 0.1 1.8e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 OAJ14531.1 - 1e-19 70.2 0.1 4.7e-19 68.1 0.1 2.1 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) PMI_typeI PF01238.21 OAJ14532.1 - 1.2e-110 370.3 0.0 3e-110 368.9 0.0 1.6 1 1 0 1 1 1 1 Phosphomannose isomerase type I ILVD_EDD PF00920.21 OAJ14533.1 - 1.8e-199 663.7 0.1 2.1e-199 663.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family MPC PF03650.13 OAJ14534.1 - 1.5e-40 137.7 0.1 1.8e-40 137.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MARVEL PF01284.23 OAJ14535.1 - 3.2e-11 43.4 12.0 4.5e-11 43.0 12.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Hol_Tox PF16935.5 OAJ14535.1 - 0.29 11.2 2.9 2.4 8.3 0.7 2.4 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) Snf7 PF03357.21 OAJ14536.1 - 2.9e-30 105.1 18.0 2.9e-30 105.1 18.0 1.6 1 1 1 2 2 2 1 Snf7 DcpS_C PF11969.8 OAJ14537.1 - 1.5e-29 102.7 0.1 2.4e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 OAJ14537.1 - 1.4e-24 86.9 0.0 2.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 OAJ14537.1 - 0.045 14.5 0.2 0.12 13.2 0.2 1.6 1 0 0 1 1 1 0 HIT domain HD_4 PF13328.6 OAJ14537.1 - 0.076 12.7 0.1 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 HD domain IPK PF03770.16 OAJ14538.1 - 4.2e-38 131.2 0.0 9.9e-22 77.8 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase Sugar_tr PF00083.24 OAJ14539.1 - 1.3e-40 139.6 9.8 1.5e-40 139.4 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ14539.1 - 8.9e-16 57.7 14.5 1.1e-15 57.4 14.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_45 PF02015.16 OAJ14540.1 - 1.3e-50 172.3 3.9 1.9e-50 171.7 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.14 OAJ14540.1 - 0.0082 15.6 12.0 0.013 14.9 12.0 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.22 OAJ14540.1 - 0.039 13.2 3.4 0.049 12.9 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PDR_CDR PF06422.12 OAJ14540.1 - 0.081 12.8 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 CDR ABC transporter Glyco_hydro_45 PF02015.16 OAJ14541.1 - 1.5e-48 165.5 8.0 1.7e-48 165.3 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 FAA_hydrolase PF01557.18 OAJ14542.1 - 5.2e-56 189.7 0.0 5.9e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NMO PF03060.15 OAJ14543.1 - 1.6e-50 172.4 3.7 2.8e-50 171.6 3.7 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAJ14543.1 - 6.7e-08 31.9 4.9 1.7e-07 30.6 4.9 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAJ14543.1 - 7.3e-05 22.0 1.9 0.00014 21.0 1.9 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IF2_N PF04760.15 OAJ14543.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mito_carr PF00153.27 OAJ14544.1 - 1.2e-63 211.0 5.1 7.3e-24 83.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sorb PF02208.16 OAJ14544.1 - 0.3 11.0 1.4 0.55 10.1 1.4 1.4 1 0 0 1 1 1 0 Sorbin homologous domain Tim17 PF02466.19 OAJ14545.1 - 3.2e-09 37.2 7.9 4.7e-09 36.6 7.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Hpt PF01627.23 OAJ14546.1 - 3.8e-08 33.5 0.0 6.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Hpt domain SOG2 PF10428.9 OAJ14546.1 - 7.4 5.6 11.9 6.7 5.8 10.7 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Ribonuc_red_lgC PF02867.15 OAJ14547.1 - 6.8e-183 608.9 0.0 8.6e-183 608.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAJ14547.1 - 6.6e-24 83.7 0.0 1.8e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAJ14547.1 - 2e-18 66.7 0.3 4.7e-18 65.5 0.3 1.7 1 0 0 1 1 1 1 ATP cone domain Abhydrolase_3 PF07859.13 OAJ14560.1 - 4.2e-18 66.0 0.0 3.9e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ14560.1 - 1.4e-08 34.4 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 OAJ14560.1 - 1.9e-05 23.8 0.0 5.4e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 OAJ14560.1 - 2.3e-05 25.1 0.7 3.1e-05 24.7 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 OAJ14560.1 - 0.043 13.6 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 OAJ14560.1 - 0.047 13.0 0.1 7.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Secretory lipase Esterase PF00756.20 OAJ14560.1 - 0.075 12.7 0.1 3.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Putative esterase Esterase_phd PF10503.9 OAJ14560.1 - 0.11 11.9 0.3 16 4.9 0.1 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase TFIIA PF03153.13 OAJ14561.1 - 0.0019 18.3 13.4 0.0019 18.3 13.4 3.5 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OAJ14561.1 - 0.0067 15.8 12.5 0.014 14.8 12.5 1.5 1 0 0 1 1 1 1 BUD22 Linker_histone PF00538.19 OAJ14561.1 - 0.015 15.6 0.0 0.14 12.5 0.0 2.2 1 1 0 1 1 1 0 linker histone H1 and H5 family MAD PF05557.13 OAJ14562.1 - 0.036 12.4 0.0 0.046 12.1 0.0 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein TPR_2 PF07719.17 OAJ14564.1 - 2.6e-06 27.1 1.7 0.0007 19.5 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ14564.1 - 1.1e-05 25.1 1.8 0.0023 17.7 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ14564.1 - 0.0056 16.3 0.3 0.028 14.1 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 OAJ14564.1 - 0.0069 16.5 0.7 0.018 15.3 0.1 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4523 PF15023.6 OAJ14564.1 - 0.079 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Med3 PF11593.8 OAJ14564.1 - 0.089 12.0 2.3 0.11 11.7 2.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_14 PF13428.6 OAJ14564.1 - 0.1 13.5 1.6 0.34 11.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ14564.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OAJ14565.1 - 8.7e-25 86.7 0.1 7.1e-24 83.8 0.2 2.5 2 0 0 2 2 2 1 Thioredoxin Apolipoprotein PF01442.18 OAJ14565.1 - 9.1e-05 22.4 27.0 0.013 15.4 13.3 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Thioredoxin_2 PF13098.6 OAJ14565.1 - 0.00016 22.1 0.0 0.0009 19.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ14565.1 - 0.014 15.3 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 OAJ14565.1 - 0.015 15.5 0.0 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 OAJ14565.1 - 0.021 14.2 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ14565.1 - 0.03 14.6 0.0 0.17 12.3 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like Ish1 PF10281.9 OAJ14565.1 - 0.22 11.9 1.1 6.5 7.1 0.1 2.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein eIF2A PF08662.11 OAJ14566.1 - 1.7e-39 135.7 0.3 5.5e-35 121.0 0.0 4.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 OAJ14566.1 - 3.4e-06 26.8 0.1 8.1e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 OAJ14566.1 - 3.8e-06 27.1 0.3 51 4.3 0.0 7.2 6 2 1 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ14566.1 - 0.0085 16.9 3.1 4.1 8.4 0.0 5.4 5 1 1 6 6 6 1 WD domain, G-beta repeat GCV_T PF01571.21 OAJ14567.1 - 0.14 11.5 0.0 0.68 9.2 0.0 1.9 1 1 0 1 1 1 0 Aminomethyltransferase folate-binding domain Ribosomal_60s PF00428.19 OAJ14568.1 - 2.9e-27 95.1 11.2 3.4e-27 94.8 11.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Metallophos_3 PF14582.6 OAJ14568.1 - 0.14 11.5 0.4 0.17 11.2 0.4 1.3 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF3824 PF12868.7 OAJ14568.1 - 0.34 11.6 3.1 0.51 11.0 3.1 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Sec6 PF06046.13 OAJ14569.1 - 1.4e-144 482.6 0.0 2.3e-144 481.9 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 OAJ14569.1 - 0.0015 17.6 4.2 0.0027 16.7 1.5 2.2 2 0 0 2 2 2 1 Vps53-like, N-terminal Stanniocalcin PF03298.13 OAJ14569.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Stanniocalcin family Pkinase PF00069.25 OAJ14570.1 - 3.5e-73 246.2 0.0 4.7e-73 245.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14570.1 - 3.9e-42 144.3 0.0 5.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14570.1 - 6.4e-10 38.8 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ14570.1 - 0.057 12.3 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAJ14570.1 - 0.065 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OAJ14571.1 - 0.0018 17.7 0.0 0.05 12.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase W2 PF02020.18 OAJ14572.1 - 2e-11 43.9 7.9 2e-11 43.9 7.9 2.9 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAJ14572.1 - 2.1e-09 36.7 3.0 0.00043 19.9 1.4 3.9 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAJ14572.1 - 4.7e-05 23.1 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 OAJ14572.1 - 7.6e-05 22.4 5.7 0.015 15.1 0.6 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAJ14572.1 - 0.00076 18.5 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 OAJ14572.1 - 0.008 16.5 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain AhpC-TSA PF00578.21 OAJ14573.1 - 4.4e-32 110.6 0.0 5.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ14573.1 - 2e-13 50.3 0.0 2.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAJ14573.1 - 3.9e-11 42.6 0.2 7.7e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 OAJ14573.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme TPR_16 PF13432.6 OAJ14574.1 - 1.8e-07 31.7 0.6 0.11 13.2 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ14574.1 - 1.2e-06 28.9 5.1 0.0061 17.0 0.3 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14574.1 - 3.4e-05 23.6 1.5 0.0033 17.4 0.0 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ14574.1 - 0.00011 22.7 6.3 0.69 10.9 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14574.1 - 0.0009 19.7 4.0 0.011 16.3 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ14574.1 - 0.0093 15.8 0.4 0.087 12.7 0.3 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ14574.1 - 0.052 13.4 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 OAJ14574.1 - 0.058 13.1 0.2 3.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_12 PF13424.6 OAJ14574.1 - 0.079 13.3 3.1 0.25 11.6 0.0 3.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ14574.1 - 0.1 12.7 0.9 1.3 9.2 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ14574.1 - 2 9.3 0.0 2 9.3 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_S19 PF00203.21 OAJ14575.1 - 8.5e-32 108.9 0.2 1.1e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 OAJ14575.1 - 0.22 11.6 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH PUF PF00806.19 OAJ14582.1 - 3e-14 51.8 0.0 0.044 13.5 0.0 6.6 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat TPR_2 PF07719.17 OAJ14583.1 - 4e-28 95.2 14.2 0.00017 21.5 0.1 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ14583.1 - 9.4e-28 94.9 8.5 0.00012 21.7 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 OAJ14583.1 - 3.3e-21 75.2 1.3 9.1e-21 73.8 0.5 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_16 PF13432.6 OAJ14583.1 - 1.5e-18 67.2 16.9 1e-06 29.2 0.1 6.1 4 3 3 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ14583.1 - 2.1e-18 66.6 15.3 5.3e-05 23.7 0.7 6.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ14583.1 - 5.1e-17 61.1 11.3 0.055 14.3 0.0 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14583.1 - 4.6e-16 58.9 13.6 1.3e-06 28.6 0.2 5.7 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ14583.1 - 6.8e-15 54.0 14.6 0.037 14.2 0.2 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ14583.1 - 1.9e-11 44.0 10.1 0.0084 16.3 1.5 4.6 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ14583.1 - 2.5e-10 39.7 1.5 0.071 13.2 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ14583.1 - 2.7e-10 39.8 17.5 7.9e-07 28.7 0.1 6.0 6 1 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 OAJ14583.1 - 2.6e-09 37.1 4.2 0.013 15.6 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14583.1 - 3.6e-06 27.2 17.3 0.5 11.1 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ14583.1 - 6.2e-05 22.5 6.9 0.037 13.4 0.9 3.5 1 1 1 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 OAJ14583.1 - 0.00068 19.8 8.5 1.6 9.3 0.0 6.0 5 2 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAJ14583.1 - 0.011 15.8 5.9 2.1 8.4 1.2 3.8 3 2 0 3 3 3 0 Putative TPR-like repeat TPM_phosphatase PF04536.14 OAJ14583.1 - 0.024 14.8 1.8 11 6.2 0.1 3.5 3 0 0 3 3 3 0 TPM domain Fis1_TPR_C PF14853.6 OAJ14583.1 - 0.031 14.3 10.6 0.039 14.0 0.2 4.6 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 OAJ14583.1 - 0.033 14.3 11.5 0.83 9.8 0.3 4.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 OAJ14583.1 - 0.061 13.2 20.9 1.9 8.5 0.4 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ14583.1 - 0.062 13.4 3.2 0.77 9.8 0.4 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) RPT PF13446.6 OAJ14583.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 A repeated domain in UCH-protein GATase1_like PF07090.11 OAJ14583.1 - 0.074 12.5 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 1 0 Putative glutamine amidotransferase TPR_4 PF07721.14 OAJ14583.1 - 0.16 12.7 9.7 0.39 11.5 0.6 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat SMBP PF16785.5 OAJ14583.1 - 0.18 12.0 16.2 0.097 12.9 2.6 4.4 3 1 1 4 4 4 0 Small metal-binding protein DUF1840 PF08895.11 OAJ14583.1 - 0.2 12.0 8.3 0.079 13.3 1.6 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF1840) Bot1p PF12298.8 OAJ14584.1 - 2.1e-24 86.6 0.1 2.1e-24 86.6 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 OAJ14584.1 - 0.021 15.0 0.0 0.021 15.0 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 CPSase_L_D2 PF02786.17 OAJ14585.1 - 1.6e-53 181.4 0.0 2.5e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 OAJ14585.1 - 3.1e-43 148.1 0.1 6.7e-39 133.9 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_N PF00289.22 OAJ14585.1 - 3.1e-23 82.4 0.0 9.6e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ14585.1 - 8.6e-22 77.3 0.0 2e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ14585.1 - 1.5e-16 60.0 0.2 4.4e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ14585.1 - 3.1e-06 26.9 1.9 0.0046 16.7 0.8 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like ATPgrasp_ST PF14397.6 OAJ14585.1 - 0.00075 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 OAJ14585.1 - 0.0014 19.3 0.6 1.7 9.4 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein DUF2118 PF09891.9 OAJ14585.1 - 0.05 13.6 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 OAJ14585.1 - 0.058 13.3 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Diphthamide_syn PF01866.17 OAJ14587.1 - 7.7e-87 291.5 0.0 6.8e-50 170.2 0.0 3.0 1 1 1 2 2 2 2 Putative diphthamide synthesis protein Abhydrolase_6 PF12697.7 OAJ14588.1 - 0.0004 21.0 0.0 0.0008 20.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CbiK PF06180.11 OAJ14588.1 - 0.14 11.5 0.0 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) Arrestin_N PF00339.29 OAJ14589.1 - 0.00044 20.3 0.2 0.0034 17.5 0.1 2.1 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OAJ14589.1 - 0.002 17.4 0.0 0.0053 16.0 0.0 1.6 1 0 0 1 1 1 1 Rgp1 Glyco_hydro_cc PF11790.8 OAJ14590.1 - 2.6e-54 184.3 3.3 3.4e-54 183.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EI24 PF07264.11 OAJ14591.1 - 0.17 12.1 11.1 0.31 11.3 11.1 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) MRP_L53 PF10780.9 OAJ14592.1 - 0.14 12.3 0.1 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 CoA_binding_3 PF13727.6 OAJ14592.1 - 0.25 11.3 0.0 0.59 10.1 0.0 1.5 1 0 0 1 1 1 0 CoA-binding domain ABC_tran PF00005.27 OAJ14593.1 - 8.6e-45 152.6 0.0 1.3e-28 100.2 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ14593.1 - 2e-32 112.9 26.7 6.9e-25 88.2 10.8 3.0 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ14593.1 - 1.6e-11 44.1 1.1 0.00028 20.4 0.1 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ14593.1 - 5.2e-08 32.5 0.4 0.0029 17.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ14593.1 - 6.9e-08 33.2 0.1 0.0028 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 OAJ14593.1 - 7.8e-06 26.4 0.5 0.028 14.8 0.4 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ14593.1 - 2.9e-05 24.4 0.5 0.034 14.4 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAJ14593.1 - 0.00012 22.0 0.1 0.84 9.4 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OAJ14593.1 - 0.00046 19.3 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.23 OAJ14593.1 - 0.00052 20.1 0.1 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 OAJ14593.1 - 0.0006 19.6 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ14593.1 - 0.0013 18.8 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 OAJ14593.1 - 0.0015 18.3 0.1 0.02 14.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 OAJ14593.1 - 0.0034 17.5 0.0 0.0094 16.1 0.0 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 OAJ14593.1 - 0.0082 16.1 0.1 2.1 8.2 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 OAJ14593.1 - 0.011 15.2 0.6 0.11 11.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 OAJ14593.1 - 0.019 15.2 0.0 6.4 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ14593.1 - 0.042 13.4 0.5 4 7.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 OAJ14593.1 - 0.08 11.8 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_ATPase PF09818.9 OAJ14593.1 - 0.096 11.5 0.1 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Septin PF00735.18 OAJ14593.1 - 0.23 10.7 0.0 6.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 OAJ14593.1 - 0.24 11.8 0.7 4.9 7.6 0.0 3.1 2 1 0 2 2 2 0 RNA helicase TMEM154 PF15102.6 OAJ14593.1 - 0.49 10.3 0.0 0.49 10.3 0.0 3.3 3 0 0 3 3 2 0 TMEM154 protein family ABC_tran PF00005.27 OAJ14594.1 - 3.1e-37 128.1 0.1 1e-29 103.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ14594.1 - 1.2e-26 94.0 10.0 1.6e-26 93.6 10.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 OAJ14594.1 - 6.3e-08 32.3 0.7 8.4e-05 22.1 0.1 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ14594.1 - 0.00084 19.6 0.3 0.0037 17.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 OAJ14594.1 - 0.002 18.3 0.7 0.019 15.0 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 OAJ14594.1 - 0.0038 17.6 0.3 0.011 16.1 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAJ14594.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_30 PF13604.6 OAJ14594.1 - 0.012 15.3 0.4 0.067 12.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ14594.1 - 0.017 14.9 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ14594.1 - 0.021 15.3 0.5 0.063 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 OAJ14594.1 - 0.027 14.3 0.1 0.45 10.3 0.0 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OAJ14594.1 - 0.03 13.4 0.0 0.082 12.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 OAJ14594.1 - 0.045 12.7 0.1 0.088 11.7 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 OAJ14594.1 - 0.12 12.4 0.4 2.9 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAJ14594.1 - 0.16 11.6 0.3 9.9 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain EI24 PF07264.11 OAJ14594.1 - 8.1 6.7 13.9 0.92 9.7 9.1 1.7 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Ku PF02735.16 OAJ14606.1 - 2.1e-32 112.5 0.0 1.8e-28 99.7 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAJ14606.1 - 2.9e-14 53.4 0.1 5.2e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 OAJ14606.1 - 9e-07 28.5 0.1 2.2e-06 27.3 0.0 1.7 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.14 OAJ14606.1 - 1.5e-05 25.6 0.2 0.0055 17.4 0.0 3.0 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Nop53 PF07767.11 OAJ14606.1 - 0.0087 15.5 0.4 0.018 14.5 0.4 1.4 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) 4HB_MCP_1 PF12729.7 OAJ14606.1 - 0.019 14.5 0.1 0.045 13.3 0.1 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Spt5_N PF11942.8 OAJ14606.1 - 0.15 13.1 4.9 0.72 10.9 3.8 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Rxt3 PF08642.10 OAJ14607.1 - 1.1e-16 61.7 0.0 1.1e-16 61.7 0.0 5.2 4 2 1 5 5 5 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAJ14607.1 - 0.035 14.2 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 LCCL domain Leuk-A4-hydro_C PF09127.11 OAJ14608.1 - 6.1e-39 132.6 0.0 1e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 OAJ14608.1 - 2.6e-34 118.7 0.0 3.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ14608.1 - 3.9e-21 76.1 0.0 5.5e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ribonuclease_3 PF00636.26 OAJ14609.1 - 2.8e-36 124.3 0.1 3.8e-17 62.8 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 OAJ14609.1 - 1.1e-21 76.8 0.1 4.8e-21 74.7 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 OAJ14609.1 - 2.9e-18 66.3 0.0 3.6e-09 36.8 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 OAJ14609.1 - 2.8e-17 63.1 0.0 7.5e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ14609.1 - 1.7e-13 50.7 0.0 3.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ14609.1 - 5.3e-13 49.3 0.3 1.2e-12 48.2 0.3 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 OAJ14609.1 - 3.9e-05 22.5 0.6 6.7e-05 21.8 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 OAJ14609.1 - 4.7e-05 23.7 0.1 0.00017 21.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain dsrm PF00035.26 OAJ14609.1 - 0.0015 19.2 0.0 0.0039 17.9 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif PAZ PF02170.22 OAJ14609.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain SWI2_SNF2 PF18766.1 OAJ14609.1 - 0.0036 17.0 1.5 0.0043 16.7 0.3 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase IFT57 PF10498.9 OAJ14609.1 - 0.12 11.3 1.9 0.23 10.4 1.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ZapB PF06005.12 OAJ14609.1 - 1.1 9.7 3.5 3.3 8.2 3.5 1.8 1 0 0 1 1 1 0 Cell division protein ZapB bVLRF1 PF18826.1 OAJ14610.1 - 8.8e-43 145.7 0.0 1.5e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank PF00023.30 OAJ14610.1 - 0.068 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 OAJ14610.1 - 0.19 12.3 0.0 0.41 11.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NICE-1 PF15845.5 OAJ14610.1 - 0.29 11.9 7.3 0.11 13.3 2.9 2.7 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family CBFD_NFYB_HMF PF00808.23 OAJ14611.1 - 1.6e-13 50.7 0.4 2.9e-13 49.9 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ14611.1 - 0.018 15.4 1.6 0.018 15.4 1.6 2.9 2 2 1 3 3 3 0 Core histone H2A/H2B/H3/H4 PK PF00224.21 OAJ14613.1 - 2.2e-160 533.2 1.5 2.8e-160 532.9 1.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAJ14613.1 - 3.3e-37 127.3 0.0 9.1e-37 125.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAJ14613.1 - 0.00012 21.3 0.8 0.00047 19.4 0.9 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAJ14613.1 - 0.0063 15.6 0.4 0.059 12.4 0.0 2.2 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 OAJ14613.1 - 0.025 14.0 0.0 0.05 13.0 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.22 OAJ14614.1 - 5.3e-32 109.5 1.1 5.3e-20 71.0 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAJ14614.1 - 0.0021 17.8 0.1 1.7 8.4 0.0 2.3 2 1 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 OAJ14614.1 - 0.0066 16.5 0.1 3 8.0 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 OAJ14614.1 - 0.018 15.2 0.1 3 8.0 0.0 3.0 2 2 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 OAJ14614.1 - 0.019 15.2 0.1 0.1 12.9 0.1 2.1 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAJ14614.1 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THOC2_N PF16134.5 OAJ14615.1 - 1.9e-119 400.1 0.0 6e-119 398.5 0.0 1.7 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAJ14615.1 - 5.2e-72 242.6 3.3 8.1e-70 235.4 3.3 2.3 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAJ14615.1 - 3.8e-24 84.5 0.1 9e-24 83.3 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Cnd2 PF05786.14 OAJ14625.1 - 2e-164 549.3 1.7 8.8e-130 434.7 0.0 4.0 2 1 1 3 3 3 3 Condensin complex subunit 2 DUF4152 PF13680.6 OAJ14625.1 - 0.00014 21.4 0.1 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) ATP-synt_E PF05680.12 OAJ14626.1 - 2e-20 72.9 0.1 2.2e-20 72.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain LdpA_C PF12617.8 OAJ14626.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Complex1_30kDa PF00329.19 OAJ14627.1 - 2.2e-46 157.4 0.0 3e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Oxysterol_BP PF01237.18 OAJ14628.1 - 2e-115 385.6 0.0 2e-115 385.6 0.0 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 OAJ14628.1 - 9.4e-16 57.9 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ14628.1 - 1.6e-05 25.3 0.0 3.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PH domain FF PF01846.19 OAJ14629.1 - 3.2e-20 72.1 15.5 3.9e-06 26.9 0.3 6.0 5 2 0 5 5 5 4 FF domain RhoGAP-FF1 PF16512.5 OAJ14629.1 - 0.0015 19.2 2.5 0.19 12.4 0.1 3.8 3 0 0 3 3 3 1 p190-A and -B Rho GAPs FF domain DUF3752 PF12572.8 OAJ14630.1 - 5e-14 53.1 38.6 1.4e-12 48.4 16.8 4.0 2 1 2 4 4 4 2 Protein of unknown function (DUF3752) Pkinase PF00069.25 OAJ14632.1 - 1.1e-33 116.7 0.0 1.7e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14632.1 - 3.8e-20 72.3 0.0 5.8e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-bind_5 PF13873.6 OAJ14632.1 - 0.017 15.2 0.0 3.9 7.6 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Pkinase_fungal PF17667.1 OAJ14632.1 - 0.25 10.0 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase NAD_Gly3P_dh_C PF07479.14 OAJ14633.1 - 1.6e-46 158.1 0.1 3e-46 157.2 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OAJ14633.1 - 3e-46 157.2 0.0 7.2e-46 156.0 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OAJ14633.1 - 3.4e-05 24.3 0.8 0.00097 19.7 0.8 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OAJ14633.1 - 0.019 14.6 0.3 0.94 9.0 0.0 2.4 1 1 1 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Perilipin PF03036.16 OAJ14634.1 - 5e-06 25.8 0.9 0.01 14.9 0.0 2.6 1 1 1 2 2 2 2 Perilipin family Apolipoprotein PF01442.18 OAJ14634.1 - 0.0071 16.2 2.1 0.022 14.6 2.1 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OAJ14634.1 - 0.32 11.1 3.0 0.88 9.7 1.8 2.3 3 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAJ14634.1 - 0.61 10.7 3.6 1.2 9.7 1.1 2.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF1958 PF09211.10 OAJ14635.1 - 0.058 13.7 0.0 0.081 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) TFIIE_beta PF02186.15 OAJ14635.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TFIIE beta subunit core domain Glyco_hydro_47 PF01532.20 OAJ14636.1 - 1.6e-116 389.9 0.2 1.9e-116 389.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_H_Exchanger PF00999.21 OAJ14638.1 - 1.7e-65 221.3 21.2 2.1e-65 221.0 21.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAJ14638.1 - 0.22 11.7 2.0 0.41 10.8 0.8 2.1 2 0 0 2 2 2 0 YrhC-like protein Microvir_J PF04726.13 OAJ14639.1 - 0.002 18.0 1.4 0.0093 15.9 1.8 1.8 2 0 0 2 2 2 1 Microvirus J protein Mem_trans PF03547.18 OAJ14640.1 - 3.3e-39 134.4 2.0 2.1e-35 121.9 0.0 2.4 2 1 0 2 2 2 2 Membrane transport protein Insulin_TMD PF17870.1 OAJ14640.1 - 1.5 9.0 4.7 13 6.0 0.2 2.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TFIIE-A_C PF11521.8 OAJ14641.1 - 0.036 14.4 0.4 0.036 14.4 0.4 3.9 3 1 1 4 4 4 0 C-terminal general transcription factor TFIIE alpha SET PF00856.28 OAJ14641.1 - 0.69 10.3 4.1 2.2 8.7 4.1 2.1 1 1 0 1 1 1 0 SET domain DDRGK PF09756.9 OAJ14641.1 - 1.3 8.5 13.9 2.5 7.6 13.9 1.4 1 0 0 1 1 1 0 DDRGK domain Plasmodium_Vir PF05795.11 OAJ14641.1 - 2.9 7.2 5.4 18 4.6 1.8 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein HsbA PF12296.8 OAJ14653.1 - 1.8e-18 67.1 14.5 1.8e-18 67.1 14.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A HsbA PF12296.8 OAJ14654.1 - 6.6e-16 58.8 9.9 1.1e-15 58.2 9.9 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A AadA_C PF18280.1 OAJ14654.1 - 0.27 11.4 1.8 0.6 10.3 0.1 2.2 1 1 1 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain HsbA PF12296.8 OAJ14656.1 - 1.5e-19 70.6 15.6 1.5e-19 70.6 15.6 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A AD PF09793.9 OAJ14656.1 - 0.11 12.6 0.1 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Anticodon-binding domain HsbA PF12296.8 OAJ14657.1 - 3.2e-19 69.5 16.5 3.2e-19 69.5 16.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A RVT_N PF13655.6 OAJ14657.1 - 0.076 13.3 1.2 11 6.3 0.2 2.3 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase HsbA PF12296.8 OAJ14658.1 - 2.1e-19 70.1 14.3 2.1e-19 70.1 14.3 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Cupin_8 PF13621.6 OAJ14659.1 - 9e-28 97.7 0.0 4.8e-27 95.3 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAJ14659.1 - 1.2e-09 38.2 0.0 5.7e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OAJ14659.1 - 0.00037 20.9 0.0 0.0074 16.7 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF866 PF05907.13 OAJ14660.1 - 3e-46 157.1 0.4 3.4e-46 157.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.11 OAJ14660.1 - 0.0045 17.1 1.6 0.04 14.0 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) SelP_N PF04592.14 OAJ14661.1 - 9.1 5.6 14.9 27 4.1 14.9 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TPP_enzyme_N PF02776.18 OAJ14662.1 - 4.4e-54 182.7 0.0 4.4e-54 182.7 0.0 2.7 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAJ14662.1 - 2.7e-48 163.6 0.1 4.2e-47 159.8 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAJ14662.1 - 3.3e-42 143.5 0.5 1.1e-41 141.8 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 OAJ14662.1 - 0.017 14.9 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RhoGAP PF00620.27 OAJ14663.1 - 2.3e-06 27.5 0.0 2.6e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 RhoGAP domain FCH PF00611.23 OAJ14663.1 - 0.041 14.2 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain MFS_1 PF07690.16 OAJ14664.1 - 8.6e-50 169.6 29.8 9.3e-46 156.4 16.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ14664.1 - 5.5e-10 38.7 2.0 5.5e-10 38.7 2.0 3.2 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAJ14664.1 - 8.5e-07 27.6 0.4 3e-06 25.8 0.3 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family VIT1 PF01988.19 OAJ14664.1 - 0.047 13.6 6.9 3.1 7.6 0.1 2.7 2 2 0 2 2 2 0 VIT family Dexa_ind PF15198.6 OAJ14664.1 - 0.15 12.2 0.0 0.71 10.0 0.0 2.2 1 0 0 1 1 1 0 Dexamethasone-induced DUF21 PF01595.20 OAJ14664.1 - 8.6 6.0 14.7 0.32 10.7 0.2 3.1 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain LIP PF03583.14 OAJ14665.1 - 1.8e-47 162.0 0.0 2.5e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ14665.1 - 0.075 12.3 0.0 0.21 10.8 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ14665.1 - 0.097 12.3 0.1 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ14665.1 - 0.11 12.4 0.4 0.26 11.1 0.4 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Bacillus_PapR PF05968.11 OAJ14676.1 - 0.082 12.8 1.9 0.32 10.9 0.3 2.4 2 0 0 2 2 2 0 Bacillus PapR protein MRP-L27 PF09809.9 OAJ14677.1 - 2.1e-06 27.6 0.7 4.5e-05 23.3 0.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 ABC_tran PF00005.27 OAJ14678.1 - 1.6e-47 161.5 0.3 8.1e-23 81.4 0.0 2.9 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ14678.1 - 6.1e-21 74.2 2.9 6.1e-21 74.2 2.9 2.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 OAJ14678.1 - 1.7e-16 60.9 7.6 0.0011 18.9 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ14678.1 - 9.3e-09 35.0 2.0 0.32 10.4 0.1 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ14678.1 - 1.6e-08 34.1 0.7 0.0073 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ14678.1 - 2.6e-08 34.6 11.8 0.0035 17.9 0.0 4.0 4 1 0 4 4 3 2 AAA domain AAA_15 PF13175.6 OAJ14678.1 - 2.5e-07 30.7 2.7 0.02 14.6 0.0 4.5 2 2 1 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 OAJ14678.1 - 3.6e-07 30.7 0.1 0.024 15.0 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 OAJ14678.1 - 8.3e-07 29.4 0.0 0.061 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OAJ14678.1 - 1.1e-06 28.7 0.4 0.0093 16.0 0.1 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ14678.1 - 7.5e-06 26.3 0.4 0.078 13.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 OAJ14678.1 - 8e-06 25.9 0.8 0.044 13.7 0.1 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 OAJ14678.1 - 0.00019 21.2 0.5 0.18 11.5 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 OAJ14678.1 - 0.00023 20.9 0.2 1.7 8.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAJ14678.1 - 0.00026 21.5 1.0 0.68 10.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 OAJ14678.1 - 0.00032 20.6 0.3 0.23 11.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 OAJ14678.1 - 0.00042 20.5 0.0 1.5 8.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 OAJ14678.1 - 0.00074 20.0 0.3 0.51 10.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 OAJ14678.1 - 0.00076 18.5 0.0 0.21 10.5 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 OAJ14678.1 - 0.00091 18.5 0.0 1.1 8.4 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain AAA_5 PF07728.14 OAJ14678.1 - 0.0014 18.6 0.3 2 8.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 OAJ14678.1 - 0.0015 18.9 1.5 1.6 9.2 0.1 3.3 3 0 0 3 3 3 1 RNA helicase cobW PF02492.19 OAJ14678.1 - 0.0021 17.7 0.3 0.57 9.7 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 OAJ14678.1 - 0.0028 16.8 0.1 0.57 9.2 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein Roc PF08477.13 OAJ14678.1 - 0.0031 17.7 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 OAJ14678.1 - 0.0048 16.9 0.0 15 5.7 0.0 3.9 3 1 1 4 4 4 0 AAA domain MobB PF03205.14 OAJ14678.1 - 0.0052 16.7 3.4 4.3 7.2 0.0 3.7 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 OAJ14678.1 - 0.0064 15.9 0.0 0.48 9.7 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.15 OAJ14678.1 - 0.0079 16.1 1.3 7.6 6.4 0.1 3.5 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 OAJ14678.1 - 0.0087 15.7 0.0 0.87 9.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 OAJ14678.1 - 0.012 14.9 0.9 7.4 5.7 0.0 3.2 3 0 0 3 3 3 0 Septin FeoB_N PF02421.18 OAJ14678.1 - 0.012 15.1 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 OAJ14678.1 - 0.019 14.5 0.2 1.9 7.9 0.1 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region Dynamin_N PF00350.23 OAJ14678.1 - 0.022 14.9 9.7 1.7 8.7 0.0 4.2 3 2 1 4 4 3 0 Dynamin family SbcCD_C PF13558.6 OAJ14678.1 - 0.028 14.6 0.1 2.4 8.4 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 OAJ14678.1 - 0.037 13.8 0.2 3 7.5 0.0 3.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 OAJ14678.1 - 0.047 13.0 0.2 14 4.9 0.1 3.1 3 0 0 3 3 3 0 Zeta toxin GTP_EFTU PF00009.27 OAJ14678.1 - 0.065 12.8 0.0 10 5.6 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 OAJ14678.1 - 0.067 12.8 0.3 12 5.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain SRP54 PF00448.22 OAJ14678.1 - 0.091 12.4 2.3 2.9 7.5 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 OAJ14678.1 - 0.11 12.2 1.9 1.8 8.3 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 OAJ14678.1 - 0.12 12.2 0.5 23 4.7 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_27 PF13514.6 OAJ14678.1 - 0.13 11.8 1.3 12 5.5 0.0 2.9 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAJ14678.1 - 0.21 11.6 8.2 2 8.5 0.1 4.1 4 1 1 5 5 4 0 Helicase HerA, central domain TsaE PF02367.17 OAJ14678.1 - 0.31 11.1 3.1 10 6.1 0.1 3.7 3 1 1 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 OAJ14678.1 - 0.6 7.6 6.5 2.4 5.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 OAJ14678.1 - 6.5 5.3 12.2 2.7 6.5 0.1 3.5 3 2 0 3 3 3 0 AAA domain Response_reg PF00072.24 OAJ14679.1 - 2.8e-18 66.1 0.0 7.7e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ14679.1 - 3e-16 59.9 0.1 5.3e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ14679.1 - 1.6e-07 31.3 0.2 7.5e-07 29.1 0.2 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAJ14679.1 - 0.0012 19.4 0.0 0.0083 16.8 0.0 2.5 2 0 0 2 2 2 1 GAF domain APG9 PF04109.16 OAJ14680.1 - 1.7e-195 650.6 0.0 2e-195 650.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Bim_N PF06773.11 OAJ14680.1 - 0.3 10.8 3.2 1.4 8.7 3.2 2.2 1 0 0 1 1 1 0 Bim protein N-terminus DUF5383 PF17355.2 OAJ14680.1 - 0.33 11.3 1.8 0.53 10.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5383) PMM PF03332.13 OAJ14682.1 - 1e-101 339.3 0.3 1.2e-101 339.1 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OAJ14682.1 - 7.6e-05 22.6 0.0 0.0014 18.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 OAJ14682.1 - 0.012 15.7 0.1 0.038 14.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Sec7 PF01369.20 OAJ14683.1 - 7.4e-30 104.0 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ14683.1 - 8.8e-07 29.4 0.1 7.8e-06 26.4 0.1 2.3 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAJ14683.1 - 0.0054 17.1 0.3 0.0054 17.1 0.3 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Dehydrin PF00257.19 OAJ14683.1 - 0.035 14.7 0.2 0.035 14.7 0.2 4.2 5 0 0 5 5 5 0 Dehydrin Spt20 PF12090.8 OAJ14683.1 - 1.4 8.4 7.8 3.1 7.3 7.8 1.5 1 0 0 1 1 1 0 Spt20 family Mpp10 PF04006.12 OAJ14684.1 - 1.7 7.0 12.4 2 6.8 12.4 1.0 1 0 0 1 1 1 0 Mpp10 protein GSH_synth_ATP PF03917.17 OAJ14686.1 - 2.6e-112 375.3 0.0 3.2e-111 371.7 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAJ14686.1 - 6.2e-28 97.3 0.0 1.1e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ribosomal_S8e PF01201.22 OAJ14687.1 - 1.2e-46 158.3 2.5 1.6e-46 157.9 1.9 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e DUF1708 PF08101.11 OAJ14707.1 - 9.8e-09 34.9 0.1 1.1e-08 34.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ14707.1 - 0.00062 19.6 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain GET2 PF08690.10 OAJ14709.1 - 0.0068 16.1 1.2 0.0068 16.1 1.2 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.12 OAJ14709.1 - 0.061 13.1 5.4 0.069 12.9 5.4 1.1 1 0 0 1 1 1 0 Pex19 protein family zf-LITAF-like PF10601.9 OAJ14710.1 - 7.6 6.9 7.4 5 7.5 0.7 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain RNA_pol_Rpo13 PF12136.8 OAJ14711.1 - 0.17 11.8 5.7 0.24 11.3 1.3 2.9 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain TpcC PF12642.7 OAJ14711.1 - 0.2 11.4 0.5 0.43 10.3 0.5 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC START PF01852.19 OAJ14712.1 - 0.0002 20.9 0.0 0.00054 19.4 0.0 1.7 1 1 0 1 1 1 1 START domain Q_salvage PF10343.9 OAJ14713.1 - 6.7e-09 35.7 0.1 1.4e-05 24.9 0.0 2.5 3 0 0 3 3 3 2 Potential Queuosine, Q, salvage protein family Pyr_redox_2 PF07992.14 OAJ14714.1 - 2.6e-39 135.2 0.0 4.8e-25 88.4 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ14714.1 - 1.6e-12 47.8 0.0 9.8e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ14714.1 - 0.0019 18.4 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Lycopene_cycl PF05834.12 OAJ14714.1 - 0.0062 15.6 0.5 2.4 7.1 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ14714.1 - 0.019 15.2 0.0 18 5.7 0.0 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OAJ14714.1 - 0.019 15.4 0.0 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ14714.1 - 0.037 13.3 0.0 22 4.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ14714.1 - 0.064 12.3 0.0 6.5 5.7 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain Attacin_N PF03768.15 OAJ14714.1 - 0.079 13.1 1.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Attacin, N-terminal region K_oxygenase PF13434.6 OAJ14714.1 - 0.099 11.8 0.0 2.2 7.3 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) F-box-like PF12937.7 OAJ14715.1 - 0.00038 20.3 0.7 0.00083 19.2 0.7 1.6 1 0 0 1 1 1 1 F-box-like ACPS PF01648.20 OAJ14717.1 - 4.4e-10 39.7 0.0 1.6e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ribonuclease_3 PF00636.26 OAJ14718.1 - 2.1e-06 28.3 0.0 3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain P22_Cro PF14549.6 OAJ14718.1 - 0.14 12.1 0.0 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro GTP1_OBG PF01018.22 OAJ14728.1 - 5e-39 133.4 1.0 1.9e-28 99.0 1.7 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 OAJ14728.1 - 6.2e-18 65.0 0.0 6.2e-18 65.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ14728.1 - 0.00034 20.2 0.2 0.00099 18.7 0.2 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B STIMATE PF12400.8 OAJ14729.1 - 1e-39 136.0 5.9 1.4e-39 135.4 5.9 1.2 1 0 0 1 1 1 1 STIMATE family R3H PF01424.22 OAJ14730.1 - 4.9e-13 48.9 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 R3H domain DAP3 PF10236.9 OAJ14731.1 - 1.4e-38 132.9 0.0 3.6e-38 131.5 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAJ14731.1 - 1.7e-05 25.3 2.0 4.2e-05 24.0 1.5 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ14731.1 - 0.041 14.2 0.0 1.1 9.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAJ14731.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea CAP PF00188.26 OAJ14734.1 - 5.6e-22 78.9 3.6 1.1e-21 77.9 3.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MBOAT_2 PF13813.6 OAJ14735.1 - 7.3e-05 23.0 1.8 0.0043 17.3 0.4 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family MFS_1 PF07690.16 OAJ14736.1 - 2.4e-06 26.7 22.7 2.4e-06 26.7 22.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 OAJ14736.1 - 0.66 10.1 7.2 3.2 7.9 1.2 3.3 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB CAP PF00188.26 OAJ14737.1 - 5.2e-22 79.0 3.6 1e-21 78.0 3.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RXT2_N PF08595.11 OAJ14739.1 - 0.008 16.2 12.4 0.058 13.4 0.1 3.7 4 1 0 4 4 4 2 RXT2-like, N-terminal RasGEF_N_2 PF14663.6 OAJ14739.1 - 0.069 13.5 0.2 0.14 12.6 0.2 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain LapA_dom PF06305.11 OAJ14751.1 - 0.063 13.1 10.4 5.5 6.9 0.0 5.1 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain VEK-30 PF12107.8 OAJ14751.1 - 0.29 11.1 1.4 0.72 9.8 1.4 1.7 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway HemY_N PF07219.13 OAJ14751.1 - 1.8 8.8 7.2 3.8 7.8 0.0 4.1 4 1 1 5 5 5 0 HemY protein N-terminus DUF1204 PF06721.11 OAJ14753.1 - 0.06 12.8 5.5 0.12 11.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) BING4CT PF08149.11 OAJ14754.1 - 0.22 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain AAA_12 PF13087.6 OAJ14755.1 - 2.9e-34 118.4 0.0 4.5e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ14755.1 - 9e-32 110.9 0.2 1.9e-31 109.8 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ14755.1 - 3.1e-10 40.5 0.0 7.4e-09 36.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ14755.1 - 1.6e-08 34.5 0.1 0.00012 21.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OAJ14755.1 - 3.5e-06 26.5 0.0 2.3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 OAJ14755.1 - 0.00076 19.3 0.7 3 7.5 0.0 3.7 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAJ14755.1 - 0.004 17.5 0.5 0.04 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain UvrD_C PF13361.6 OAJ14755.1 - 0.0052 16.2 0.1 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 OAJ14755.1 - 0.0083 16.1 0.0 0.041 13.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SelB-wing_2 PF09106.11 OAJ14755.1 - 0.011 15.9 0.6 9.9 6.5 0.0 3.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix PhoH PF02562.16 OAJ14755.1 - 0.012 15.1 0.0 0.033 13.6 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 OAJ14755.1 - 0.035 14.5 0.1 0.87 10.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ14755.1 - 0.035 14.4 0.1 0.73 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 OAJ14755.1 - 0.036 13.9 0.0 0.22 11.4 0.0 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAJ14755.1 - 0.038 13.5 0.1 0.12 11.9 0.1 1.9 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_7 PF12775.7 OAJ14755.1 - 0.045 13.3 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAJ14755.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Helicase_RecD PF05127.14 OAJ14755.1 - 0.069 13.0 0.1 0.72 9.7 0.0 2.4 3 0 0 3 3 3 0 Helicase HARP PF07443.13 OAJ14755.1 - 0.1 12.3 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 HepA-related protein (HARP) EmrE PF13536.6 OAJ14755.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter zf-CCCH PF00642.24 OAJ14756.1 - 2.2e-06 27.4 3.0 2.2e-06 27.4 3.0 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ14756.1 - 0.0001 22.2 5.1 0.00017 21.5 5.1 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 OAJ14756.1 - 0.00047 20.5 5.9 0.00047 20.5 5.9 1.9 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 OAJ14756.1 - 0.0044 17.2 0.1 0.0075 16.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAJ14756.1 - 0.013 15.3 3.7 0.02 14.7 3.7 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger Peroxidase_2 PF01328.17 OAJ14757.1 - 1.8e-53 181.9 0.0 2.4e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 SepF PF04472.12 OAJ14757.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell division protein SepF LEAP-2 PF07359.11 OAJ14758.1 - 1.1 9.2 4.9 23 4.9 0.6 3.2 2 1 1 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) H_lectin PF09458.10 OAJ14759.1 - 5.3e-21 74.6 0.3 6.7e-09 35.8 0.1 3.3 3 0 0 3 3 3 2 H-type lectin domain DUF948 PF06103.11 OAJ14759.1 - 0.059 13.6 0.1 0.37 11.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 OAJ14759.1 - 3.9 6.7 6.9 2.1 7.6 1.1 2.7 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 OAJ14759.1 - 6.8 6.8 9.6 1.1e+02 2.8 9.6 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cation_efflux PF01545.21 OAJ14761.1 - 8.5e-27 94.2 8.5 1.1e-26 93.8 8.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ14761.1 - 0.00015 21.8 0.1 0.00035 20.6 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Med8 PF10232.9 OAJ14761.1 - 0.096 12.3 0.6 0.19 11.3 0.6 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1772 PF08592.11 OAJ14762.1 - 8.4e-15 55.3 2.9 8.4e-15 55.3 2.9 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) CDT1_C PF16679.5 OAJ14763.1 - 9.3e-15 54.8 2.5 2.4e-12 47.1 0.0 3.3 3 1 0 3 3 3 2 DNA replication factor Cdt1 C-terminal domain Med4 PF10018.9 OAJ14764.1 - 5.5e-16 58.8 8.5 5.5e-16 58.8 8.5 1.9 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Med11 PF10280.9 OAJ14764.1 - 0.00041 20.8 1.3 0.00041 20.8 1.3 2.6 2 1 0 2 2 2 1 Mediator complex protein SUIM_assoc PF16619.5 OAJ14764.1 - 0.027 14.5 1.8 0.027 14.5 1.8 3.7 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2967 PF11179.8 OAJ14764.1 - 2.6 6.0 12.1 0.22 9.6 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) IBN_N PF03810.19 OAJ14775.1 - 1.8e-06 27.8 0.0 1.1e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 OAJ14775.1 - 0.08 11.4 0.0 0.19 10.2 0.0 1.6 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus HEAT PF02985.22 OAJ14775.1 - 0.41 11.0 6.2 69 4.1 0.1 5.5 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 OAJ14775.1 - 0.94 10.1 10.4 4.8 7.8 0.1 5.8 6 0 0 6 6 6 0 HEAT-like repeat Ribosomal_L38e PF01781.18 OAJ14776.1 - 1.3e-33 114.9 0.5 1.6e-33 114.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family zf-C2H2_jaz PF12171.8 OAJ14777.1 - 6.1e-10 39.1 2.8 1e-09 38.4 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ14777.1 - 3.1e-05 24.2 1.7 5e-05 23.6 1.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ14777.1 - 0.00043 20.6 0.2 0.00061 20.1 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 OAJ14777.1 - 0.0063 16.8 0.3 0.0081 16.4 0.3 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) Orn_Arg_deC_N PF02784.16 OAJ14778.1 - 9.2e-73 244.6 0.0 1.4e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAJ14778.1 - 4e-15 55.8 0.0 7.3e-15 55.0 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 OAJ14778.1 - 0.073 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain SGT1 PF07093.11 OAJ14779.1 - 1.1e-24 86.9 0.0 1.1e-24 86.9 0.0 6.1 4 2 1 6 6 6 3 SGT1 protein ADK PF00406.22 OAJ14781.1 - 4.3e-43 147.0 0.0 5.4e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ14781.1 - 7.6e-22 78.2 0.0 1.6e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ14781.1 - 2e-13 50.1 0.0 4.6e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 OAJ14781.1 - 0.0082 16.3 0.0 0.017 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ14781.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAJ14781.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Flavin_Reduct PF01613.18 OAJ14782.1 - 1.3e-29 103.2 0.3 1.9e-29 102.7 0.3 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_S11 PF00411.19 OAJ14783.1 - 1.8e-43 147.4 0.9 2.8e-43 146.8 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 MBOAT PF03062.19 OAJ14784.1 - 7.9e-53 180.0 18.1 7.9e-53 180.0 18.1 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family HSP70 PF00012.20 OAJ14785.1 - 8.4e-65 219.1 3.0 7.8e-40 136.6 0.0 2.6 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 OAJ14785.1 - 0.00019 20.4 0.0 0.00095 18.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 OAJ14785.1 - 0.00096 17.9 0.0 0.36 9.4 0.0 2.2 2 0 0 2 2 2 2 Actin US30 PF17624.2 OAJ14785.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function Hydantoinase_A PF01968.18 OAJ14785.1 - 0.15 11.3 3.2 0.17 11.1 0.4 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Retrotran_gag_2 PF14223.6 OAJ14786.1 - 2.4e-08 33.7 0.1 3.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ14786.1 - 3.8e-06 26.4 0.4 8.6e-06 25.3 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) LMBR1 PF04791.16 OAJ14786.1 - 0.027 13.4 0.1 0.029 13.3 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec20 PF03908.13 OAJ14786.1 - 0.17 11.8 1.3 9.6 6.2 0.1 3.0 2 1 1 3 3 3 0 Sec20 DotU PF09850.9 OAJ14786.1 - 0.58 9.8 3.3 0.85 9.3 1.3 2.1 1 1 0 1 1 1 0 Type VI secretion system protein DotU Baculo_11_kDa PF06143.11 OAJ14786.1 - 5.2 6.7 5.5 7.5 6.2 4.6 1.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family TPR_10 PF13374.6 OAJ14787.1 - 1.9e-32 110.2 37.3 0.00021 21.0 0.1 12.4 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ14787.1 - 8.8e-32 109.2 52.3 1.5e-06 28.4 5.9 11.9 6 2 5 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ14787.1 - 6.4e-10 38.4 18.2 0.23 11.6 0.1 10.3 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ14787.1 - 0.00065 19.7 14.6 26 5.3 0.1 10.5 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ14787.1 - 0.0012 18.6 6.2 3.9 7.5 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat SeqA PF03925.13 OAJ14787.1 - 0.0016 18.4 1.3 6.6 6.7 0.0 5.3 6 1 0 6 6 5 1 SeqA protein C-terminal domain Vps4_C PF09336.10 OAJ14787.1 - 0.0018 18.2 0.0 23 5.1 0.0 5.9 7 0 0 7 7 7 0 Vps4 C terminal oligomerisation domain TPR_7 PF13176.6 OAJ14787.1 - 0.0098 15.9 13.6 1.3 9.2 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat Hydant_A_N PF05378.13 OAJ14787.1 - 0.074 12.8 0.1 18 5.0 0.0 4.2 2 1 2 4 4 4 0 Hydantoinase/oxoprolinase N-terminal region DUF3856 PF12968.7 OAJ14787.1 - 0.1 12.7 17.7 2.1 8.4 1.3 5.7 1 1 5 7 7 7 0 Domain of Unknown Function (DUF3856) ThiD2 PF17792.1 OAJ14787.1 - 1.3 9.5 16.9 12 6.3 0.2 7.3 6 2 3 10 10 10 0 ThiD2 family ParE_toxin PF05016.15 OAJ14787.1 - 2.1 9.0 5.9 46 4.7 0.5 4.7 2 2 1 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE TPR_4 PF07721.14 OAJ14787.1 - 2.2 9.1 33.1 29 5.7 0.2 10.4 12 1 0 12 12 10 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAJ14800.1 - 5.1e-25 88.1 70.9 3.3e-21 75.6 37.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ytp1 PF10355.9 OAJ14801.1 - 6.7e-50 169.8 22.3 2.2e-47 161.6 22.3 2.9 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ14801.1 - 1.2e-24 86.1 2.0 1.2e-24 86.1 2.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) BUD22 PF09073.10 OAJ14802.1 - 0.64 9.3 16.8 0.76 9.0 16.8 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAJ14802.1 - 1 8.7 13.9 1.3 8.4 13.9 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.6 OAJ14802.1 - 1.4 8.5 11.5 0.66 9.6 0.3 2.2 1 1 1 2 2 2 0 FAM176 family Nop14 PF04147.12 OAJ14802.1 - 4.6 5.3 13.3 6.1 4.9 13.3 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ14802.1 - 9.2 4.7 10.5 11 4.4 10.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HisG PF01634.18 OAJ14803.1 - 2e-41 141.6 0.0 5e-41 140.3 0.0 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAJ14803.1 - 1.2e-23 83.1 0.1 2.1e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain PMI_typeI PF01238.21 OAJ14804.1 - 2.3e-55 188.3 0.0 3.5e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 OAJ14804.1 - 0.09 12.5 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Cupin domain MFS_1 PF07690.16 OAJ14805.1 - 5.8e-28 97.8 33.7 1.8e-27 96.2 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAJ14805.1 - 0.00084 18.7 4.1 0.00084 18.7 4.1 2.6 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF5326 PF17260.2 OAJ14805.1 - 0.85 9.8 0.0 0.85 9.8 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5326) AAA PF00004.29 OAJ14808.1 - 2.5e-40 138.0 0.0 5e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ14808.1 - 1.3e-08 34.5 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ14808.1 - 6.4e-07 29.9 0.5 0.00014 22.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ14808.1 - 1.1e-06 28.7 0.1 1.2e-05 25.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ14808.1 - 2.1e-06 27.6 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ14808.1 - 2.7e-05 24.7 0.0 0.0006 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ14808.1 - 4e-05 23.9 0.4 0.0043 17.3 0.3 2.9 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ14808.1 - 0.00022 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ14808.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAJ14808.1 - 0.00064 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ14808.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 OAJ14808.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 OAJ14808.1 - 0.003 17.9 0.0 0.0076 16.6 0.0 1.8 1 1 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 OAJ14808.1 - 0.0033 16.8 0.1 0.01 15.2 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ14808.1 - 0.004 16.9 0.1 0.0067 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 OAJ14808.1 - 0.0042 16.5 0.0 0.96 8.8 0.0 2.3 1 1 0 2 2 2 1 Bacterial TniB protein AAA_28 PF13521.6 OAJ14808.1 - 0.0044 17.3 0.0 0.0081 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ14808.1 - 0.0049 16.4 0.2 0.021 14.4 0.2 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OAJ14808.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 OAJ14808.1 - 0.0081 16.0 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Bacterial dnaA protein DUF815 PF05673.13 OAJ14808.1 - 0.0093 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAJ14808.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 OAJ14808.1 - 0.014 15.0 0.3 0.084 12.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAJ14808.1 - 0.014 15.3 0.2 0.21 11.5 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 OAJ14808.1 - 0.019 14.3 0.0 0.15 11.4 0.0 2.1 1 1 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ14808.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 OAJ14808.1 - 0.029 14.4 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OAJ14808.1 - 0.048 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ14808.1 - 0.06 13.2 0.0 0.18 11.7 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) S1FA PF04689.13 OAJ14808.1 - 0.076 13.2 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA AAA_21 PF13304.6 OAJ14808.1 - 0.094 12.5 0.3 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PhoH PF02562.16 OAJ14808.1 - 0.1 12.0 0.2 0.24 10.8 0.1 1.4 1 1 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.21 OAJ14808.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase IPT PF01745.16 OAJ14808.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ABC_tran PF00005.27 OAJ14808.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 OAJ14808.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 OAJ14808.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Homeobox_KN PF05920.11 OAJ14809.1 - 1.9e-17 62.9 3.5 3.6e-17 62.0 3.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAJ14809.1 - 1e-05 25.2 0.9 2.5e-05 24.0 0.9 1.6 1 0 0 1 1 1 1 Homeodomain RhoGEF PF00621.20 OAJ14810.1 - 1.4e-38 133.0 0.0 3.2e-38 131.8 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OAJ14810.1 - 3.4e-10 39.9 0.0 0.00014 21.7 0.0 2.7 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 OAJ14810.1 - 0.0078 16.7 0.0 0.028 14.9 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 OAJ14810.1 - 0.035 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Pannexin_like PF12534.8 OAJ14810.1 - 0.29 10.2 4.3 0.35 9.9 0.0 2.3 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 BUD22 PF09073.10 OAJ14810.1 - 0.32 10.3 18.9 0.5 9.7 18.9 1.2 1 0 0 1 1 1 0 BUD22 SH3_1 PF00018.28 OAJ14811.1 - 3.2e-17 61.8 0.3 5.4e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ14811.1 - 2.5e-16 59.3 0.2 5.4e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 OAJ14811.1 - 2.7e-16 59.4 0.0 6.6e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 OAJ14811.1 - 4.6e-10 39.0 0.0 0.00014 21.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 OAJ14811.1 - 2.3e-05 24.1 0.1 6e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 OAJ14811.1 - 0.088 12.4 0.0 16 5.3 0.0 2.8 2 0 0 2 2 2 0 EF hand Rx_N PF18052.1 OAJ14811.1 - 0.46 10.8 4.7 1.4 9.2 4.7 1.8 1 0 0 1 1 1 0 Rx N-terminal domain NDK PF00334.19 OAJ14822.1 - 2.9e-53 179.5 0.0 3.6e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase F-box-like PF12937.7 OAJ14824.1 - 5.6e-05 22.9 0.2 0.00038 20.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like HEAT PF02985.22 OAJ14825.1 - 4.9e-06 26.3 2.3 10 6.7 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 OAJ14825.1 - 0.0015 18.6 0.0 0.0054 16.8 0.0 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 OAJ14825.1 - 0.002 17.5 0.0 0.0043 16.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.6 OAJ14825.1 - 0.68 10.5 2.8 1.3 9.7 0.3 2.8 3 0 0 3 3 3 0 HEAT-like repeat ThrE PF06738.12 OAJ14826.1 - 1.9e-50 171.5 24.5 4.1e-50 170.4 6.8 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ14826.1 - 1.9e-10 41.0 10.7 1.9e-10 41.0 10.7 2.6 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE ELYS PF13934.6 OAJ14827.1 - 0.15 12.0 0.4 2 8.3 0.1 2.0 2 0 0 2 2 2 0 Nuclear pore complex assembly DUF5401 PF17380.2 OAJ14828.1 - 0.25 9.4 7.5 0.35 8.9 7.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) eIF3_subunit PF08597.10 OAJ14828.1 - 0.65 9.9 11.5 1.2 9.0 11.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ish1 PF10281.9 OAJ14829.1 - 0.0086 16.4 3.7 9 6.7 0.1 3.7 3 0 0 3 3 3 2 Putative stress-responsive nuclear envelope protein Nop25 PF09805.9 OAJ14829.1 - 3.7 8.0 27.9 0.19 12.2 5.0 4.0 4 0 0 4 4 4 0 Nucleolar protein 12 (25kDa) Serinc PF03348.15 OAJ14830.1 - 8.9e-151 502.6 7.7 1.1e-150 502.4 7.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YqhR PF11085.8 OAJ14830.1 - 0.029 14.3 3.6 0.038 13.9 2.4 1.8 1 1 0 1 1 1 0 Conserved membrane protein YqhR GerA PF03323.13 OAJ14830.1 - 8.4 4.7 5.5 0.69 8.3 0.6 1.6 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Pyridoxal_deC PF00282.19 OAJ14842.1 - 4.1e-65 219.9 0.0 6.3e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ14842.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Phosphoesterase PF04185.14 OAJ14843.1 - 1.7e-26 93.2 2.5 1.5e-25 90.2 2.5 1.9 1 1 0 1 1 1 1 Phosphoesterase family Histone PF00125.24 OAJ14844.1 - 8.9e-23 81.1 0.2 1.2e-22 80.7 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ14844.1 - 4.8e-07 30.0 0.1 9.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAJ14844.1 - 0.00045 20.7 0.0 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 OAJ14844.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 OAJ14844.1 - 0.098 12.3 0.2 0.3 10.7 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain FSA_C PF10479.9 OAJ14845.1 - 0.18 9.9 19.3 0.22 9.6 19.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Shisa PF13908.6 OAJ14845.1 - 0.2 11.9 4.4 0.29 11.4 4.4 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF5349 PF17298.2 OAJ14845.1 - 9.7 5.8 11.8 13 5.4 11.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Pil1 PF13805.6 OAJ14847.1 - 1.7e-33 116.3 0.2 2.7e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 OAJ14847.1 - 0.012 16.1 0.3 0.025 15.1 0.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 OAJ14847.1 - 0.04 12.5 0.3 0.056 12.0 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PP1_bind PF15276.6 OAJ14847.1 - 0.06 13.7 1.0 0.22 11.9 1.0 2.0 1 0 0 1 1 1 0 Protein phosphatase 1 binding GrpE PF01025.19 OAJ14847.1 - 0.066 12.9 0.3 0.22 11.2 0.2 1.8 1 1 1 2 2 2 0 GrpE bZIP_1 PF00170.21 OAJ14847.1 - 0.16 12.1 1.0 0.3 11.2 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor UPF0242 PF06785.11 OAJ14847.1 - 0.18 11.9 0.3 0.33 11.0 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 OAJ14847.1 - 0.2 12.1 0.7 0.41 11.1 0.7 1.4 1 0 0 1 1 1 0 Snapin/Pallidin GTP-bdg_M PF16360.5 OAJ14847.1 - 0.28 11.8 1.7 0.49 11.0 0.1 2.2 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region GMP_synt_C PF00958.22 OAJ14848.1 - 3.2e-43 145.7 0.0 6.5e-43 144.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAJ14848.1 - 2.8e-37 128.4 0.0 4.4e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAJ14848.1 - 1e-10 41.1 0.1 1.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAJ14848.1 - 1.4e-09 38.1 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 OAJ14848.1 - 0.00066 18.6 0.2 0.0012 17.8 0.2 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 OAJ14848.1 - 0.0068 16.0 0.1 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 OAJ14848.1 - 0.0084 15.6 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 OAJ14848.1 - 0.053 13.3 0.3 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 OAJ14848.1 - 0.094 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase Trehalase PF01204.18 OAJ14849.1 - 4.1e-172 573.6 0.5 5.2e-172 573.2 0.5 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAJ14849.1 - 3.8e-16 58.5 0.1 6.1e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Histone_H2A_C PF16211.5 OAJ14850.1 - 1.7e-18 66.0 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ14850.1 - 9e-17 61.7 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ14850.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RA PF00788.23 OAJ14851.1 - 6.1e-11 42.8 0.0 1e-08 35.7 0.0 2.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 OAJ14851.1 - 1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ14851.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Cpn60_TCP1 PF00118.24 OAJ14852.1 - 1.2e-154 515.6 1.7 1.4e-154 515.4 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 OAJ14852.1 - 0.63 10.2 3.8 16 5.7 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ14853.1 - 3.4e-31 108.5 0.3 5.5e-31 107.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ14853.1 - 5.9e-17 61.7 0.3 1.2e-16 60.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 OAJ14853.1 - 3e-16 59.3 0.0 7e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 OAJ14853.1 - 1.8e-13 51.1 0.4 2.1e-12 47.7 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ14853.1 - 8.9e-07 29.2 0.4 1.6e-06 28.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GSHPx PF00255.19 OAJ14854.1 - 3.3e-32 110.3 0.2 4.1e-32 110.0 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 OAJ14854.1 - 6.7e-05 22.6 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ14854.1 - 0.00043 20.2 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family ING PF12998.7 OAJ14855.1 - 3.5e-13 50.0 0.8 9.9e-06 26.1 0.1 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ14855.1 - 1.7e-06 27.8 6.6 2.8e-06 27.1 6.6 1.4 1 0 0 1 1 1 1 PHD-finger AT_hook PF02178.19 OAJ14855.1 - 0.13 12.2 6.9 0.82 9.8 6.9 2.5 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 OAJ14865.1 - 4.3e-33 114.8 0.0 5.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14865.1 - 5.6e-18 65.2 0.0 9.2e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14865.1 - 2.4e-06 27.1 0.0 3.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 OAJ14865.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Med5 PF08689.10 OAJ14866.1 - 3.8e-23 81.3 0.0 4.2e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 Mediator complex subunit Med5 adh_short_C2 PF13561.6 OAJ14866.1 - 0.018 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 OAJ14867.1 - 8.9e-08 31.1 0.0 1.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.12 OAJ14868.1 - 2.7e-25 88.4 4.2 2.7e-25 88.4 4.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ14868.1 - 3.5e-12 46.4 0.0 6e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ14868.1 - 0.00068 19.0 0.1 0.0017 17.8 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAJ14868.1 - 0.0031 16.8 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAJ14868.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.19 OAJ14868.1 - 0.047 12.4 0.0 0.093 11.4 0.0 1.4 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF983 PF06170.12 OAJ14868.1 - 0.55 10.7 1.9 0.7 10.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF983) NUDE_C PF04880.13 OAJ14869.1 - 7.9e-14 52.5 8.1 7.9e-14 52.5 8.1 3.2 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 OAJ14869.1 - 0.00021 19.0 13.8 0.00029 18.5 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 OAJ14869.1 - 0.0014 18.7 21.7 0.002 18.2 2.8 3.3 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein ZapB PF06005.12 OAJ14869.1 - 0.0018 18.7 5.4 0.0018 18.7 5.4 3.7 2 1 1 3 3 2 1 Cell division protein ZapB Filament PF00038.21 OAJ14869.1 - 0.0032 17.1 5.9 0.0032 17.1 5.9 2.3 1 1 1 2 2 2 1 Intermediate filament protein DivIC PF04977.15 OAJ14869.1 - 0.016 14.9 13.1 0.25 11.1 0.5 3.6 2 1 1 3 3 3 0 Septum formation initiator DUF2353 PF09789.9 OAJ14869.1 - 0.021 14.2 18.9 0.023 14.1 9.5 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TolA_bind_tri PF16331.5 OAJ14869.1 - 0.024 14.7 0.2 0.024 14.7 0.2 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation PRKG1_interact PF15898.5 OAJ14869.1 - 0.03 15.2 10.4 0.03 15.2 10.4 2.7 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain FPP PF05911.11 OAJ14869.1 - 0.036 12.3 23.2 0.22 9.7 11.0 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Med9 PF07544.13 OAJ14869.1 - 0.064 13.4 7.8 0.15 12.1 2.7 3.3 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 DUF4686 PF15742.5 OAJ14869.1 - 0.067 12.3 14.7 0.11 11.6 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Phage_GP20 PF06810.11 OAJ14869.1 - 0.08 12.7 15.1 0.045 13.6 4.1 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 DUF4407 PF14362.6 OAJ14869.1 - 0.78 9.0 9.0 3.4 6.9 9.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 OAJ14869.1 - 0.81 10.3 17.9 2.9 8.5 1.7 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal HMMR_N PF15905.5 OAJ14869.1 - 0.88 9.0 21.3 3.1 7.2 21.6 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Prefoldin_2 PF01920.20 OAJ14869.1 - 1.3 9.0 21.2 1.4 8.9 1.8 4.0 2 1 1 3 3 3 0 Prefoldin subunit Golgin_A5 PF09787.9 OAJ14869.1 - 1.7 8.1 21.3 3.2 7.2 11.9 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Laminin_II PF06009.12 OAJ14869.1 - 2.1 8.4 15.5 1.8 8.6 3.4 3.5 2 1 2 4 4 4 0 Laminin Domain II DUF948 PF06103.11 OAJ14869.1 - 2.6 8.4 10.8 0.67 10.3 0.9 3.1 3 1 2 5 5 4 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 OAJ14869.1 - 3.3 8.2 14.6 9.3 6.7 0.8 4.6 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 OAJ14869.1 - 5 4.9 9.6 7.7 4.3 9.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rab5-bind PF09311.11 OAJ14869.1 - 5.4 6.3 18.2 13 5.0 18.2 1.6 1 1 0 1 1 1 0 Rabaptin-like protein Occludin_ELL PF07303.13 OAJ14869.1 - 6.7 7.5 12.3 14 6.4 2.9 3.1 2 1 1 3 3 3 0 Occludin homology domain HALZ PF02183.18 OAJ14869.1 - 6.8 7.0 9.0 0.35 11.1 2.2 2.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper TACC_C PF05010.14 OAJ14869.1 - 7 6.4 19.2 4 7.2 15.0 2.4 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 OAJ14869.1 - 7.7 5.3 20.7 0.69 8.7 11.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 OAJ14869.1 - 8.6 6.4 19.3 2.6 8.1 9.5 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Fungal_TACC PF12709.7 OAJ14869.1 - 8.7 6.9 12.9 10 6.7 0.9 3.6 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins UreF PF01730.16 OAJ14870.1 - 6.1e-19 68.9 0.1 1e-18 68.2 0.1 1.3 1 0 0 1 1 1 1 UreF Pro_CA PF00484.19 OAJ14871.1 - 3e-37 128.3 0.0 4.7e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF4702 PF15774.5 OAJ14871.1 - 0.0033 16.4 2.0 0.0049 15.9 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4702) Mucin PF01456.17 OAJ14871.1 - 0.34 10.9 10.7 0.56 10.2 10.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein XPG_N PF00752.17 OAJ14872.1 - 1.8e-34 118.2 0.0 3.4e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ14872.1 - 1.8e-31 108.4 0.0 4.5e-31 107.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OAJ14872.1 - 2.2e-07 31.4 0.0 6.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAJ14872.1 - 0.00087 19.8 0.0 0.0027 18.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Fe_dep_repr_C PF02742.15 OAJ14872.1 - 0.022 14.8 0.0 1.7 8.8 0.0 2.7 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain HHH PF00633.23 OAJ14872.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Transposase_20 PF02371.16 OAJ14872.1 - 0.14 12.4 0.7 0.53 10.6 0.0 2.3 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family Peptidase_M20 PF01546.28 OAJ14873.1 - 1.8e-25 89.9 0.0 3.5e-25 88.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ14873.1 - 3.1e-11 43.2 0.7 1.2e-10 41.3 0.7 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3953 PF13129.6 OAJ14873.1 - 0.12 12.2 0.6 0.23 11.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) Ebp2 PF05890.12 OAJ14874.1 - 4e-76 256.1 6.5 4e-76 256.1 6.5 1.9 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 TMEM154 PF15102.6 OAJ14875.1 - 0.054 13.4 0.5 0.15 11.9 0.5 1.8 1 0 0 1 1 1 0 TMEM154 protein family DUF4533 PF15047.6 OAJ14876.1 - 0.18 11.4 2.3 0.69 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) COesterase PF00135.28 OAJ14877.1 - 4.5e-95 319.5 0.0 5.2e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ14877.1 - 6.9e-09 35.9 0.7 3.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold FMN_dh PF01070.18 OAJ14878.1 - 3.9e-101 338.6 0.1 3.6e-91 305.8 0.1 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAJ14878.1 - 3.8e-05 23.0 0.2 6.1e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ14878.1 - 0.00019 20.6 2.0 0.00033 19.8 1.6 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAJ14878.1 - 0.0059 16.0 0.7 1.2 8.4 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG TMEM51 PF15345.6 OAJ14880.1 - 7.1 6.4 7.3 6.8 6.4 2.3 2.6 3 0 0 3 3 3 0 Transmembrane protein 51 Velvet PF11754.8 OAJ14890.1 - 1.6e-43 149.5 0.0 7.4e-31 108.0 0.1 5.5 3 3 1 4 4 4 2 Velvet factor Redoxin PF08534.10 OAJ14891.1 - 8.6e-31 106.6 0.0 1e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ14891.1 - 9.6e-07 28.8 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Cellulase PF00150.18 OAJ14892.1 - 9.1e-16 58.1 2.8 1.3e-15 57.5 2.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 OAJ14892.1 - 0.011 15.1 0.1 0.05 12.9 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase CRAL_TRIO PF00650.20 OAJ14893.1 - 1.2e-11 44.6 0.0 6.9e-11 42.1 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Peptidase_M43 PF05572.13 OAJ14894.1 - 2.6e-07 30.7 0.1 5.9e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Nop14 PF04147.12 OAJ14895.1 - 0.014 13.6 19.5 0.019 13.2 19.5 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ14895.1 - 3.6 5.8 18.8 5.1 5.3 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ14895.1 - 5.6 6.3 27.4 8 5.8 27.4 1.1 1 0 0 1 1 1 0 SDA1 Oxidored_FMN PF00724.20 OAJ14896.1 - 1.3e-54 185.8 0.0 3.1e-50 171.4 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.32 OAJ14897.1 - 4.7e-12 46.2 7.3 0.00024 21.8 0.0 7.3 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ14897.1 - 6.7e-08 32.7 0.0 0.21 11.9 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain ENTH PF01417.20 OAJ14898.1 - 2.2e-47 160.2 0.1 5.1e-47 159.0 0.1 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAJ14898.1 - 0.002 17.2 2.1 0.002 17.2 2.1 2.0 2 1 0 2 2 2 1 ANTH domain UIM PF02809.20 OAJ14898.1 - 0.014 15.2 11.1 0.24 11.4 0.6 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif DDHD PF02862.17 OAJ14898.1 - 8.8 6.4 16.7 4.8 7.3 4.8 2.3 2 0 0 2 2 2 0 DDHD domain LSM PF01423.22 OAJ14899.1 - 5.6e-20 70.8 0.1 6.3e-20 70.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ14899.1 - 4.2e-06 26.8 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ14899.1 - 0.00056 19.9 0.1 0.00062 19.8 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain MFS_1 PF07690.16 OAJ14900.1 - 1e-38 133.2 23.3 1e-38 133.2 23.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HLH PF00010.26 OAJ14901.1 - 2.1e-08 34.0 0.6 3.4e-08 33.3 0.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.9 OAJ14901.1 - 0.018 15.2 0.6 0.045 14.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2423) TFIIA PF03153.13 OAJ14901.1 - 0.15 12.0 22.5 0.034 14.2 0.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.12 OAJ14901.1 - 1.3 8.3 11.2 2.1 7.6 11.2 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ14901.1 - 1.4 8.5 7.0 0.61 9.8 3.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 OAJ14901.1 - 3.6 7.1 4.5 0.44 10.1 0.4 1.7 2 0 0 2 2 2 0 PPP4R2 Catalase PF00199.19 OAJ14902.1 - 3.7e-62 210.6 0.1 4.2e-62 210.5 0.1 1.0 1 0 0 1 1 1 1 Catalase Porin_3 PF01459.22 OAJ14903.1 - 2.7e-61 207.4 0.2 3.4e-61 207.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic porin PAP2 PF01569.21 OAJ14905.1 - 0.00098 18.9 1.8 0.0024 17.6 0.7 2.1 1 1 0 1 1 1 1 PAP2 superfamily UPF0542 PF15086.6 OAJ14905.1 - 0.0023 17.8 0.1 0.0039 17.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DUF4405 PF14358.6 OAJ14905.1 - 0.82 10.3 5.3 6.5 7.4 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4405) Myb_DNA-bind_3 PF12776.7 OAJ14914.1 - 0.0051 17.8 6.5 0.068 14.2 0.1 3.6 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain Fibrillarin_2 PF10113.9 OAJ14914.1 - 0.08 11.6 0.1 0.13 10.9 0.1 1.3 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Methyltransf_25 PF13649.6 OAJ14914.1 - 4.1 8.2 4.9 2.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain RskA PF10099.9 OAJ14914.1 - 7.9 6.7 49.6 0.89 9.8 2.1 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF3915 PF13054.6 OAJ14916.1 - 0.036 14.1 1.2 0.065 13.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Rft-1 PF04506.13 OAJ14917.1 - 1.6e-111 373.6 0.0 1.9e-111 373.4 0.0 1.0 1 0 0 1 1 1 1 Rft protein Pribosyltran_N PF13793.6 OAJ14918.1 - 1.7e-43 147.3 0.0 9.8e-43 144.8 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ14918.1 - 8.4e-34 117.2 1.6 5.5e-31 108.0 0.5 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ14918.1 - 1.2e-14 54.1 0.8 3.6e-13 49.3 0.5 2.9 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ14918.1 - 0.019 14.4 0.2 0.047 13.1 0.2 1.7 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OAJ14918.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase PGI PF00342.19 OAJ14919.1 - 4.4e-226 751.2 0.1 5e-226 751.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Inhibitor_Mig-6 PF11555.8 OAJ14919.1 - 0.023 14.8 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 RabGAP-TBC PF00566.18 OAJ14920.1 - 9.2e-36 123.5 0.1 1.4e-35 122.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Period_C PF12114.8 OAJ14920.1 - 2.1 7.9 5.8 3.3 7.3 5.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region OTCace_N PF02729.21 OAJ14921.1 - 5.1e-45 153.1 0.0 7.6e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 OAJ14921.1 - 3.2e-44 150.8 0.0 4.7e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF4616 PF15394.6 OAJ14922.1 - 0.12 11.3 4.4 0.21 10.5 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Exonuc_VII_L PF02601.15 OAJ14922.1 - 0.26 10.8 8.8 0.42 10.1 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAPS_reduct PF01507.19 OAJ14923.1 - 1.8e-34 119.3 0.0 2.6e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 OAJ14924.1 - 4.8e-39 134.3 0.0 3.5e-27 95.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14924.1 - 5.6e-22 78.3 0.0 8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ14924.1 - 5.5e-08 32.0 0.0 1.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Polysacc_synt_4 PF04669.13 OAJ14925.1 - 9.6e-19 67.7 4.4 3.8e-17 62.5 4.4 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis NDUF_B12 PF08122.12 OAJ14926.1 - 4.1e-16 58.8 0.2 6e-16 58.2 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family F1F0-ATPsyn_F PF10791.9 OAJ14927.1 - 5.2e-29 100.6 0.0 6.8e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Herpes_pp85 PF04637.12 OAJ14927.1 - 1.2 7.5 2.3 1.6 7.1 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2797 PF10977.8 OAJ14928.1 - 0.025 14.5 1.0 0.025 14.5 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2797) VPS28 PF03997.12 OAJ14929.1 - 1.4e-58 197.7 0.0 2.6e-58 196.8 0.0 1.4 1 1 0 1 1 1 1 VPS28 protein SLT PF01464.20 OAJ14930.1 - 0.00067 19.3 0.1 0.015 14.9 0.0 2.5 2 1 0 2 2 2 1 Transglycosylase SLT domain Hexapep PF00132.24 OAJ14931.1 - 5.3e-10 38.6 16.8 6.2e-06 25.7 1.1 5.4 4 2 1 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ14931.1 - 1.6e-05 24.5 12.1 0.26 11.1 0.0 4.8 5 1 0 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAJ14931.1 - 0.21 10.5 0.1 0.61 9.0 0.0 1.6 1 1 1 2 2 2 0 L-fucokinase RRM_1 PF00076.22 OAJ14932.1 - 1.1e-15 57.2 0.3 2e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ14932.1 - 0.00042 19.9 0.0 0.00085 18.9 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ14932.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 OAJ14932.1 - 0.03 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF5320 PF17253.2 OAJ14932.1 - 0.13 13.3 0.5 0.54 11.4 0.5 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5320) ELO PF01151.18 OAJ14944.1 - 1.2e-54 185.5 12.8 1.4e-54 185.2 12.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family PXA PF02194.15 OAJ14945.1 - 1e-12 48.4 0.0 2.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAJ14945.1 - 3.4e-11 43.7 0.0 1e-10 42.1 0.0 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.9 OAJ14945.1 - 0.16 12.0 2.1 0.31 11.1 2.1 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) MRP_L53 PF10780.9 OAJ14946.1 - 0.054 13.7 0.2 0.092 12.9 0.2 1.4 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Aconitase PF00330.20 OAJ14948.1 - 3.6e-111 372.4 0.0 3e-110 369.4 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ14948.1 - 3.8e-21 75.8 0.0 1e-20 74.4 0.0 1.7 1 1 1 2 2 2 1 Aconitase C-terminal domain DUF5473 PF17567.2 OAJ14948.1 - 0.05 13.9 0.0 5.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Zn_clus PF00172.18 OAJ14949.1 - 0.00071 19.7 15.4 0.0013 18.8 15.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 OAJ14951.1 - 9.6e-28 97.1 28.3 2.3e-25 89.3 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapD_MoxY_N PF16448.5 OAJ14951.1 - 0.091 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain Glyco_hydro_47 PF01532.20 OAJ14952.1 - 1.1e-146 489.4 0.0 1.3e-146 489.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 OAJ14952.1 - 0.24 10.9 0.7 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Claudin_2 PF13903.6 OAJ14953.1 - 4.7 6.9 8.7 8.1 6.1 0.6 3.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Methyltransf_11 PF08241.12 OAJ14954.1 - 5.8e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ14954.1 - 2.2e-08 34.1 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ14954.1 - 2.9e-08 34.4 0.0 5.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ14954.1 - 3.2e-06 27.7 0.0 8.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ14954.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 OAJ14954.1 - 0.09 12.5 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Lysine methyltransferase Shugoshin_C PF07557.11 OAJ14955.1 - 6.4e-20 70.6 25.3 1.6e-10 40.5 5.3 3.9 3 0 0 3 3 3 3 Shugoshin C terminus RNA_pol_3_Rpc31 PF11705.8 OAJ14955.1 - 0.0099 16.2 1.2 0.0099 16.2 1.2 4.1 3 1 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 Bystin PF05291.11 OAJ14956.1 - 3.5e-129 430.3 0.0 4.4e-129 429.9 0.0 1.1 1 0 0 1 1 1 1 Bystin PPP4R2 PF09184.11 OAJ14956.1 - 0.12 11.9 10.8 0.24 11.0 10.8 1.5 1 0 0 1 1 1 0 PPP4R2 Vac_ImportDeg PF09783.9 OAJ14957.1 - 1.7e-50 171.0 0.0 1.6e-46 158.1 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein BRCT_2 PF16589.5 OAJ14958.1 - 6.2e-05 23.3 0.0 0.00015 22.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF2924 PF11149.8 OAJ14958.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2924) RIO1 PF01163.22 OAJ14969.1 - 5e-64 215.4 0.4 5e-64 215.4 0.4 2.8 2 1 0 2 2 2 1 RIO1 family YL1 PF05764.13 OAJ14969.1 - 0.12 12.5 31.9 0.031 14.4 1.4 2.8 3 0 0 3 3 3 0 YL1 nuclear protein CAP PF00188.26 OAJ14970.1 - 1.2e-21 77.8 2.9 2.2e-21 77.0 2.9 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 OAJ14971.1 - 1.1e-21 78.0 2.3 1.7e-21 77.4 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family F-box-like PF12937.7 OAJ14974.1 - 0.037 13.9 0.2 0.13 12.2 0.2 1.9 1 0 0 1 1 1 0 F-box-like Peptidase_M23 PF01551.22 OAJ14976.1 - 7.3e-05 22.9 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 JmjC PF02373.22 OAJ14977.1 - 2.6e-27 95.5 0.0 4.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ14977.1 - 1.2e-08 34.8 0.2 4.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 jmjN domain Dimer_Tnp_hAT PF05699.14 OAJ14980.1 - 1.1e-11 44.3 0.0 2.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1764 PF08576.10 OAJ14980.1 - 0.018 15.9 0.2 0.018 15.9 0.2 4.6 5 1 1 6 6 6 0 Eukaryotic protein of unknown function (DUF1764) RhoGAP PF00620.27 OAJ14982.1 - 2e-45 154.4 0.0 7.9e-45 152.4 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 OAJ14982.1 - 3.7e-13 49.5 16.3 7.7e-08 32.5 2.3 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 OAJ14982.1 - 7.9e-07 28.9 7.2 7.9e-07 28.9 7.2 3.7 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) SUIM_assoc PF16619.5 OAJ14982.1 - 2e-05 24.5 0.0 0.00054 20.0 0.0 3.3 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 UQ_con PF00179.26 OAJ14983.1 - 4.1e-16 58.9 0.0 5.5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ14983.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Actin PF00022.19 OAJ14996.1 - 2.4e-89 299.8 0.0 4.8e-88 295.5 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OAJ14996.1 - 0.11 12.9 0.0 0.4 11.1 0.0 2.1 1 1 0 1 1 1 0 Cell division protein FtsA baeRF_family10 PF18854.1 OAJ14996.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 zf-RING_2 PF13639.6 OAJ14997.1 - 1.1e-07 32.0 12.2 1.8e-07 31.4 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ14997.1 - 0.0003 20.5 8.3 0.00058 19.5 8.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAJ14997.1 - 0.00035 20.5 11.4 0.00055 19.8 11.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ14997.1 - 0.0052 16.6 10.7 0.0085 15.9 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ14997.1 - 0.011 15.6 10.4 0.017 15.0 10.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 30K_MP_C_Ter PF11330.8 OAJ14997.1 - 0.097 12.0 0.2 0.21 10.9 0.2 1.5 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins zf-rbx1 PF12678.7 OAJ14997.1 - 0.27 11.6 9.2 0.71 10.2 9.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ14997.1 - 0.6 10.0 9.7 1.2 9.1 9.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pinin_SDK_memA PF04696.13 OAJ14997.1 - 1.6 8.8 13.5 1.4 9.0 5.0 2.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region zf-C3HC4 PF00097.25 OAJ14997.1 - 1.9 8.4 11.7 3 7.8 11.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 OAJ14997.1 - 2.2 8.4 8.7 4.2 7.5 8.7 1.5 1 0 0 1 1 1 0 Zinc-finger ANAPC10 PF03256.16 OAJ14998.1 - 1.6e-45 155.1 0.0 2.2e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) XRCC1_N PF01834.16 OAJ14998.1 - 0.049 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 XRCC1 N terminal domain WD40 PF00400.32 OAJ15000.1 - 9.7e-53 175.0 14.8 7.6e-10 39.2 0.3 8.5 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15000.1 - 1.1e-13 51.2 0.8 2.2e-05 24.6 0.1 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ15000.1 - 1.6e-10 40.3 10.0 0.01 14.5 0.0 5.8 3 1 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ15000.1 - 8.7e-05 21.4 1.0 1.3 7.6 0.1 4.1 2 2 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 OAJ15000.1 - 0.071 11.6 0.0 5.1 5.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 OAJ15000.1 - 0.11 12.4 0.0 9.3 6.1 0.1 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Chitin_synth_2 PF03142.15 OAJ15001.1 - 2.6e-238 791.9 0.4 2.6e-238 791.9 0.4 1.6 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 OAJ15001.1 - 2.6e-133 445.7 0.0 1.1e-117 394.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 OAJ15001.1 - 1.5e-15 56.8 0.6 7.4e-14 51.4 0.0 3.4 4 0 0 4 4 4 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAJ15001.1 - 3.8e-14 53.1 1.5 3.8e-14 53.1 1.5 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAJ15001.1 - 8.3e-11 42.2 0.0 1.2e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 OAJ15001.1 - 3.1e-10 40.1 0.3 4.6e-06 26.7 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 OAJ15001.1 - 0.00029 20.7 0.0 0.082 12.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAJ15001.1 - 0.02 14.4 0.0 0.57 9.6 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 21 DEAD PF00270.29 OAJ15001.1 - 0.044 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OAJ15001.1 - 0.1 12.9 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Enolase_C PF00113.22 OAJ15002.1 - 2.5e-140 466.9 0.1 3.3e-140 466.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAJ15002.1 - 6.2e-57 191.4 0.0 1e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAJ15002.1 - 8.6e-09 35.3 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAJ15002.1 - 0.0089 15.2 0.1 0.018 14.2 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PBP PF01161.20 OAJ15003.1 - 3.7e-16 59.6 0.6 8.6e-16 58.4 0.6 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ndc1_Nup PF09531.10 OAJ15003.1 - 3.2 6.3 6.1 4.7 5.8 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apolipoprotein PF01442.18 OAJ15004.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mod_r PF07200.13 OAJ15005.1 - 2.6e-20 73.0 1.6 5.1e-20 72.1 1.6 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FlgN PF05130.12 OAJ15005.1 - 0.004 17.7 1.8 0.004 17.7 1.8 2.1 1 1 1 2 2 2 1 FlgN protein Herpes_UL14 PF03580.14 OAJ15005.1 - 0.027 14.7 2.8 0.03 14.6 1.0 2.0 2 1 0 2 2 2 0 Herpesvirus UL14-like protein Glyco_H_20C_C PF18088.1 OAJ15005.1 - 0.074 12.9 0.9 0.12 12.2 0.6 1.4 1 1 0 1 1 1 0 Glycoside Hydrolase 20C C-terminal domain NYD-SP28_assoc PF14775.6 OAJ15005.1 - 0.6 10.3 2.8 0.33 11.1 0.3 1.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain F-box-like PF12937.7 OAJ15006.1 - 0.00029 20.7 0.7 0.00064 19.6 0.7 1.7 1 0 0 1 1 1 1 F-box-like ELP6 PF09807.9 OAJ15008.1 - 5.7e-10 39.0 0.0 9.1e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 AAA_25 PF13481.6 OAJ15008.1 - 0.00039 20.1 0.1 0.0006 19.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain Ser_hydrolase PF06821.13 OAJ15008.1 - 0.036 13.9 0.5 8.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Methyltransf_10 PF05971.12 OAJ15009.1 - 1.9e-54 185.0 0.0 7e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase Methyltransf_31 PF13847.6 OAJ15009.1 - 0.0018 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ15009.1 - 0.032 15.0 0.0 0.077 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Thaumatin PF00314.17 OAJ15024.1 - 3.9e-17 62.6 3.1 3.9e-17 62.6 3.1 1.6 1 1 1 2 2 2 2 Thaumatin family RT_RNaseH_2 PF17919.1 OAJ15026.1 - 3.5e-22 78.3 0.0 3.6e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ15026.1 - 6.3e-22 78.2 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ15026.1 - 5.2e-17 62.1 0.0 4.3e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ15026.1 - 5.9e-16 58.3 0.1 1.3e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ15026.1 - 1e-07 32.2 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ15026.1 - 5.4e-05 23.7 0.0 0.00022 21.8 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ15026.1 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 OAJ15026.1 - 0.015 15.8 0.0 0.037 14.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ15026.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DDE_Tnp_4 PF13359.6 OAJ15027.1 - 2.1e-14 53.5 0.1 4.7e-14 52.3 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ15027.1 - 0.028 14.0 0.7 0.45 10.1 0.7 2.1 1 1 0 1 1 1 0 Transposase DDE domain DUF1325 PF07039.11 OAJ15029.1 - 5.9e-29 100.8 0.0 9.5e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 OAJ15029.1 - 0.17 12.4 0.0 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Agenet domain PhyH PF05721.13 OAJ15030.1 - 2e-09 38.0 0.0 4.4e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UCH_1 PF13423.6 OAJ15031.1 - 5.6e-79 266.0 0.0 7.1e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAJ15031.1 - 7e-15 56.0 0.0 1.2e-14 55.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 OAJ15031.1 - 0.00026 21.7 0.7 0.017 16.0 0.0 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15031.1 - 0.0016 18.7 0.0 5.9 7.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PGM_PMM_I PF02878.16 OAJ15032.1 - 1.5e-38 131.6 0.2 2.4e-38 131.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OAJ15032.1 - 9.6e-23 80.8 0.1 6.6e-22 78.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAJ15032.1 - 5.1e-13 49.2 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OAJ15032.1 - 1.5e-07 31.5 0.2 1.2e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pyridox_oxase_2 PF12766.7 OAJ15033.1 - 2.2e-20 73.1 0.4 5.3e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase ERCC4 PF02732.15 OAJ15036.1 - 2.5e-20 73.3 0.0 5.4e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.16 OAJ15036.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain EMP24_GP25L PF01105.24 OAJ15037.1 - 4.6e-33 114.7 0.0 5.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CD24 PF14984.6 OAJ15037.1 - 0.011 16.0 1.8 0.011 16.0 1.8 2.1 2 0 0 2 2 2 0 CD24 protein Trimer_CC PF08954.11 OAJ15037.1 - 0.49 10.0 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Trimerisation motif VASt PF16016.5 OAJ15038.1 - 4.1e-36 124.7 0.3 1.2e-35 123.2 0.1 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAJ15038.1 - 5.9e-26 90.6 0.1 1.6e-25 89.2 0.0 1.7 2 0 0 2 2 2 1 GRAM domain DPBB_1 PF03330.18 OAJ15051.1 - 1.5e-08 34.8 0.2 3.7e-08 33.5 0.2 1.7 1 1 0 1 1 1 1 Lytic transglycolase MFS_1 PF07690.16 OAJ15052.1 - 4.7e-39 134.3 48.0 3.3e-26 92.1 17.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF2085 PF09858.9 OAJ15052.1 - 6.2 7.4 9.9 0.62 10.6 0.1 3.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) AMP-binding PF00501.28 OAJ15053.1 - 1.3e-48 165.7 0.0 1.9e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAJ15053.1 - 2e-13 50.0 0.5 2e-13 50.0 0.5 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAJ15053.1 - 0.0042 18.0 0.2 0.0098 16.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FTO_NTD PF12933.7 OAJ15053.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FTO catalytic domain FKBP_C PF00254.28 OAJ15056.1 - 1.2e-28 99.3 0.0 2.8e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OAJ15056.1 - 1.5e-07 31.9 0.0 1.5e-07 31.9 0.0 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain PBP1_TM PF14812.6 OAJ15056.1 - 0.013 15.8 7.5 0.013 15.8 7.5 4.1 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hamartin PF04388.12 OAJ15056.1 - 4.5 5.8 6.3 6.4 5.3 6.3 1.3 1 0 0 1 1 1 0 Hamartin protein Borrelia_P83 PF05262.11 OAJ15056.1 - 4.6 5.6 21.9 6.5 5.1 21.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein KH_1 PF00013.29 OAJ15057.1 - 5.7e-93 304.8 33.5 5.2e-13 48.6 0.0 15.8 16 1 0 16 16 16 11 KH domain KH_2 PF07650.17 OAJ15057.1 - 5.7e-11 42.1 25.0 0.16 11.8 0.1 8.8 9 0 0 9 9 9 6 KH domain KH_4 PF13083.6 OAJ15057.1 - 4.8e-06 26.4 18.7 0.69 9.8 0.1 8.7 6 1 2 8 8 8 2 KH domain SLS PF14611.6 OAJ15057.1 - 0.014 15.2 13.8 3.1 7.5 0.1 6.0 6 0 0 6 6 6 0 Mitochondrial inner-membrane-bound regulator Lipoprotein_17 PF04200.12 OAJ15057.1 - 0.052 13.9 0.7 0.23 11.8 0.7 2.1 1 0 0 1 1 1 0 Lipoprotein associated domain APG17 PF04108.12 OAJ15057.1 - 0.12 11.4 1.6 2.3 7.3 0.1 2.5 2 0 0 2 2 2 0 Autophagy protein Apg17 baeRF_family5 PF18846.1 OAJ15057.1 - 0.22 11.8 1.8 64 3.8 0.1 4.2 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 Acylphosphatase PF00708.18 OAJ15057.1 - 1.8 9.0 8.3 22 5.6 0.0 5.6 6 0 0 6 6 6 0 Acylphosphatase DUF4201 PF13870.6 OAJ15058.1 - 0.00049 19.9 2.6 0.00049 19.9 2.6 8.4 4 2 2 8 8 8 1 Domain of unknown function (DUF4201) zf-C6H2 PF15801.5 OAJ15059.1 - 0.16 12.3 2.6 12 6.3 0.4 2.3 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Sugar_tr PF00083.24 OAJ15060.1 - 7.3e-36 124.0 15.2 1.5e-35 123.0 15.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ15060.1 - 6.7e-28 97.6 34.7 1.1e-27 96.9 34.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ15060.1 - 0.14 10.5 8.0 0.093 11.1 1.6 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Tim17 PF02466.19 OAJ15061.1 - 5e-25 88.0 6.6 5e-25 88.0 6.6 1.7 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TetR_C_34 PF17929.1 OAJ15073.1 - 0.042 14.0 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP68 PF16969.5 OAJ15073.1 - 0.29 10.1 2.8 0.54 9.2 2.8 1.3 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 AA_permease PF00324.21 OAJ15074.1 - 5.2e-117 391.4 30.0 6.5e-117 391.0 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ15074.1 - 1.6e-33 116.2 32.1 2.1e-33 115.8 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 OAJ15075.1 - 3.6e-70 232.0 1.3 2e-24 85.3 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein X PF00739.19 OAJ15075.1 - 0.71 10.0 3.5 38 4.4 5.8 2.4 2 0 0 2 2 2 0 Trans-activation protein X Dus PF01207.17 OAJ15076.1 - 6.5e-45 153.5 0.0 1.6e-25 89.8 0.0 3.0 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) Pkinase PF00069.25 OAJ15077.1 - 1.9e-65 220.9 0.1 5.6e-60 202.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15077.1 - 5e-36 124.3 0.1 2.3e-33 115.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 OAJ15077.1 - 3.8e-17 61.8 0.4 6.6e-17 61.0 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OAJ15077.1 - 6.1e-05 22.5 0.1 0.0001 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ15077.1 - 0.0012 17.8 0.1 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ15077.1 - 0.0013 18.7 0.0 0.0051 16.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ15077.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribosomal_L14 PF00238.19 OAJ15078.1 - 6.2e-41 139.3 2.0 7.1e-41 139.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Retrotran_gag_2 PF14223.6 OAJ15079.1 - 5.3e-20 71.5 0.0 9.4e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ15079.1 - 3.1e-17 62.9 0.0 6.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ15079.1 - 8.4e-10 38.4 0.0 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ15079.1 - 3.5e-06 26.8 1.2 3.5e-06 26.8 1.2 2.1 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.6 OAJ15079.1 - 0.00015 21.5 0.0 0.00039 20.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_6 PF15288.6 OAJ15079.1 - 0.27 11.1 2.2 0.62 10.0 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ15079.1 - 2.2 8.0 6.1 1 9.1 3.4 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SET PF00856.28 OAJ15080.1 - 7.6e-09 36.2 0.0 7.6e-09 36.2 0.0 2.5 2 1 0 2 2 2 1 SET domain Vps55 PF04133.14 OAJ15081.1 - 2.6e-41 140.3 7.2 2.9e-41 140.1 7.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 zf-RING_4 PF14570.6 OAJ15082.1 - 2.6e-22 78.4 11.6 4.8e-22 77.5 11.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAJ15082.1 - 2.2e-07 30.6 8.9 4.4e-07 29.7 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15082.1 - 3.9e-06 26.6 9.0 0.0012 18.6 9.7 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAJ15082.1 - 0.001 19.4 11.8 0.0019 18.5 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.22 OAJ15082.1 - 0.0024 17.6 0.1 0.032 14.0 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.6 OAJ15082.1 - 0.0057 16.7 3.8 0.012 15.7 3.8 1.5 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 OAJ15082.1 - 0.075 12.9 11.5 0.16 11.9 11.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ15082.1 - 0.18 11.7 11.5 0.4 10.6 11.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ15082.1 - 0.49 10.5 8.4 0.62 10.1 6.6 2.0 1 1 1 2 2 2 0 RING-type zinc-finger Baculo_IE-1 PF05290.11 OAJ15082.1 - 0.64 10.0 10.2 0.22 11.5 6.4 1.9 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Redoxin PF08534.10 OAJ15083.1 - 1.3e-05 25.0 0.0 0.00018 21.2 0.0 2.0 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 OAJ15083.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OAJ15083.1 - 0.00029 20.9 0.0 0.00061 19.9 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme Aminotran_1_2 PF00155.21 OAJ15084.1 - 1.3e-39 136.4 0.0 2.6e-39 135.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ15084.1 - 9.8e-05 21.0 0.0 0.00021 19.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fasciclin PF02469.22 OAJ15085.1 - 5.9e-41 139.7 0.0 1.1e-09 38.6 0.0 7.1 6 2 0 6 6 6 5 Fasciclin domain DUF4381 PF14316.6 OAJ15085.1 - 0.43 10.8 2.6 1.4 9.1 2.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Sec16_C PF12931.7 OAJ15086.1 - 1.2e-94 317.3 0.0 1.7e-94 316.9 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAJ15086.1 - 5.4e-16 59.2 0.0 1.9e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PfkB PF00294.24 OAJ15098.1 - 1.4e-59 201.9 0.1 1.7e-59 201.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAJ15098.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Peptidase_M17 PF00883.21 OAJ15099.1 - 0.068 12.4 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain LXG PF04740.12 OAJ15099.1 - 0.16 11.7 5.7 0.67 9.6 1.7 3.3 3 1 0 3 3 3 0 LXG domain of WXG superfamily DUF948 PF06103.11 OAJ15099.1 - 0.34 11.2 4.1 17 5.7 0.5 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Snapin_Pallidin PF14712.6 OAJ15099.1 - 2 8.9 8.9 0.46 10.9 2.1 3.0 2 1 0 2 2 2 0 Snapin/Pallidin DUF16 PF01519.16 OAJ15099.1 - 3.9 8.0 9.1 1.1 9.8 2.8 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 MFS_1 PF07690.16 OAJ15100.1 - 1.9e-30 106.0 20.4 2.9e-30 105.4 20.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.6 OAJ15100.1 - 0.12 12.5 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein RT_RNaseH PF17917.1 OAJ15101.1 - 4.1e-13 49.5 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ15101.1 - 2.1e-09 37.6 0.0 4.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ15101.1 - 3.7e-06 26.9 0.0 8.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ15102.1 - 2.5e-18 66.4 0.0 3.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ15102.1 - 5.1e-07 29.7 0.0 9.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Helicase_C PF00271.31 OAJ15103.1 - 3.7e-08 33.7 0.0 3.4e-07 30.6 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ15103.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase LMWPc PF01451.21 OAJ15109.1 - 1.1e-36 126.4 0.0 1.2e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DDE_3 PF13358.6 OAJ15111.1 - 2e-15 56.8 0.0 7.1e-15 55.0 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 OAJ15111.1 - 5.9e-12 45.2 2.3 2e-10 40.2 0.0 2.8 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 OAJ15111.1 - 4e-09 36.0 1.6 2.2e-07 30.5 0.0 3.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 OAJ15111.1 - 1.5e-08 34.7 5.9 1.7e-08 34.5 3.3 2.3 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.6 OAJ15111.1 - 1e-07 31.8 2.8 8.4e-07 28.9 0.8 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.6 OAJ15111.1 - 3.8e-05 23.7 1.6 0.00058 19.9 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 OAJ15111.1 - 5.5e-05 23.7 4.9 5.5e-05 23.7 4.9 3.4 3 1 1 4 4 3 1 Homeodomain-like domain Sigma70_r4_2 PF08281.12 OAJ15111.1 - 0.00012 21.6 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 TnsD PF15978.5 OAJ15111.1 - 0.0016 17.5 2.1 0.0032 16.5 2.1 1.5 1 0 0 1 1 1 1 Tn7-like transposition protein D GerE PF00196.19 OAJ15111.1 - 0.0017 17.9 0.0 0.0054 16.2 0.0 1.9 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family Trp_repressor PF01371.19 OAJ15111.1 - 0.0035 17.4 1.1 0.037 14.2 0.0 2.5 2 0 0 2 2 2 1 Trp repressor protein DUF3320 PF11784.8 OAJ15111.1 - 0.0062 16.5 0.6 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3320) HTH_3 PF01381.22 OAJ15111.1 - 0.0074 16.3 0.1 0.063 13.3 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix HTH_24 PF13412.6 OAJ15111.1 - 0.0097 15.5 0.0 0.036 13.6 0.0 2.0 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 OAJ15111.1 - 0.02 14.4 1.3 0.085 12.4 0.0 2.4 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 OAJ15111.1 - 0.035 13.5 0.5 1.7 8.1 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 MarR PF01047.22 OAJ15111.1 - 0.062 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 OAJ15111.1 - 0.11 12.5 0.1 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain KfrA_N PF11740.8 OAJ15111.1 - 0.12 13.1 0.8 2 9.1 0.0 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_AsnC-type PF13404.6 OAJ15111.1 - 0.13 12.1 0.6 0.54 10.1 0.0 2.3 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain HTH_40 PF14493.6 OAJ15111.1 - 0.14 12.6 0.0 0.57 10.7 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Sgf11 PF08209.11 OAJ15112.1 - 4.6e-13 48.5 0.7 4.6e-13 48.5 0.7 2.1 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 OAJ15112.1 - 0.17 11.8 1.4 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type UPF0203 PF05254.12 OAJ15127.1 - 2.8e-16 59.5 0.0 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 OAJ15127.1 - 0.064 13.5 0.3 6.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SPX PF03105.19 OAJ15127.1 - 0.18 11.7 7.1 0.18 11.7 7.1 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OAJ15127.1 - 0.2 10.5 6.5 0.21 10.4 6.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAJ15127.1 - 3.4 6.1 7.7 3.8 5.9 7.7 1.0 1 0 0 1 1 1 0 Macoilin family Raftlin PF15250.6 OAJ15128.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Raftlin PCI PF01399.27 OAJ15129.1 - 1.2e-14 54.7 0.0 3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF5528 PF17666.1 OAJ15129.1 - 0.32 10.9 0.9 8.5 6.3 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5528) zf-Tim10_DDP PF02953.15 OAJ15130.1 - 8.2e-19 67.0 0.5 1.1e-18 66.6 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger BUD22 PF09073.10 OAJ15131.1 - 9.8e-58 196.5 48.5 2.5e-57 195.2 48.5 1.6 1 1 0 1 1 1 1 BUD22 MCU PF04678.13 OAJ15131.1 - 4.7 7.3 7.9 7.9 6.5 2.9 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DA1-like PF12315.8 OAJ15133.1 - 0.045 13.1 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein DA1 AdoMet_MTase PF07757.13 OAJ15134.1 - 3.9e-31 107.7 0.0 3.8e-14 53.0 0.1 2.6 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Pec_lyase_C PF00544.19 OAJ15134.1 - 1.2e-13 51.2 5.1 1.3e-12 47.7 5.1 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAJ15134.1 - 7.8e-05 22.6 3.5 0.00067 19.5 2.7 2.1 1 1 1 2 2 2 2 Right handed beta helix region Kelch_3 PF13415.6 OAJ15135.1 - 2.2e-31 107.5 17.0 1.6e-08 34.6 0.2 7.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ15135.1 - 6.9e-31 105.7 10.3 4.7e-06 26.5 0.4 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OAJ15135.1 - 4.6e-29 100.2 16.2 6.1e-07 29.4 0.1 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ15135.1 - 6.5e-25 86.5 18.4 2.4e-08 33.4 2.4 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 OAJ15135.1 - 1.4e-24 85.5 9.6 1.3e-07 31.6 0.7 6.7 5 1 1 6 6 6 4 Kelch motif Kelch_2 PF07646.15 OAJ15135.1 - 3.7e-17 61.5 16.6 0.0014 18.5 0.5 7.0 6 1 0 6 6 6 5 Kelch motif Tropomyosin_1 PF12718.7 OAJ15135.1 - 0.0088 16.2 1.1 0.0088 16.2 1.1 6.7 4 1 3 7 7 7 1 Tropomyosin like Vac_Fusion PF02346.16 OAJ15135.1 - 8.4 6.1 8.6 3.2 7.5 0.0 3.7 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 DUF4834 PF16118.5 OAJ15135.1 - 9.5 7.3 5.8 93 4.1 5.8 2.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SNARE PF05739.19 OAJ15136.1 - 6e-16 58.2 0.1 1.2e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ15136.1 - 1.8e-07 31.0 2.5 0.0016 18.1 0.7 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 OAJ15136.1 - 0.00078 18.6 0.1 0.003 16.8 0.0 2.1 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF148 PF02520.17 OAJ15136.1 - 0.0015 18.6 2.6 0.011 15.8 0.4 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF148 FlaC_arch PF05377.11 OAJ15136.1 - 0.031 14.7 1.0 0.1 13.0 0.9 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Use1 PF09753.9 OAJ15136.1 - 0.038 13.7 1.3 0.061 13.0 0.4 1.8 2 0 0 2 2 2 0 Membrane fusion protein Use1 DUF4685 PF15737.5 OAJ15136.1 - 0.042 14.3 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) Syntaxin-6_N PF09177.11 OAJ15136.1 - 0.051 14.1 0.3 5.9 7.5 0.0 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 OAJ15136.1 - 0.063 13.9 3.8 0.068 13.8 0.3 2.8 2 2 1 3 3 3 0 SlyX DUF948 PF06103.11 OAJ15136.1 - 0.12 12.6 0.6 0.99 9.7 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 OAJ15136.1 - 0.17 12.4 2.8 0.23 12.0 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 OAJ15136.1 - 0.3 11.1 6.0 6 6.9 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.9 OAJ15136.1 - 0.48 10.7 2.6 2 8.8 0.5 2.8 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 OAJ15136.1 - 0.79 10.0 4.7 3.4 8.0 0.1 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein MCPsignal PF00015.21 OAJ15136.1 - 3.6 7.4 8.8 0.52 10.1 1.8 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Topoisom_I_N PF02919.15 OAJ15137.1 - 4.3e-80 268.2 1.8 4.3e-80 268.2 1.8 3.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAJ15137.1 - 3.5e-68 229.3 0.1 3.5e-68 229.3 0.1 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAJ15137.1 - 1.3e-17 63.4 0.6 1.9e-14 53.3 0.1 2.9 2 0 0 2 2 2 2 C-terminal topoisomerase domain SANT_DAMP1_like PF16282.5 OAJ15137.1 - 0.11 12.7 1.1 0.86 9.8 0.1 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 DAO PF01266.24 OAJ15138.1 - 4.9e-50 171.1 0.5 8.1e-50 170.4 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAJ15138.1 - 3e-45 153.2 0.1 8.2e-45 151.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 OAJ15138.1 - 9.1e-07 29.2 0.4 2e-06 28.2 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 OAJ15138.1 - 5.9e-06 25.6 6.3 6.3e-05 22.2 6.3 2.2 1 1 0 1 1 1 1 FAD binding domain EF-hand_1 PF00036.32 OAJ15138.1 - 0.00025 20.4 0.1 0.001 18.5 0.1 2.1 2 0 0 2 2 2 1 EF hand FAD_oxidored PF12831.7 OAJ15138.1 - 0.00056 19.4 1.1 0.00056 19.4 1.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase EF-hand_6 PF13405.6 OAJ15138.1 - 0.0015 18.3 0.1 0.0046 16.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain Pyr_redox_2 PF07992.14 OAJ15138.1 - 0.0028 16.9 0.7 0.0092 15.2 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.6 OAJ15138.1 - 0.0088 15.5 0.6 0.02 14.4 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 OAJ15138.1 - 0.016 15.1 0.9 0.24 11.3 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair FAD_binding_3 PF01494.19 OAJ15138.1 - 0.018 14.3 1.5 0.29 10.3 1.5 2.3 1 1 0 1 1 1 0 FAD binding domain GIDA PF01134.22 OAJ15138.1 - 0.036 13.2 0.5 0.18 10.8 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAJ15138.1 - 0.084 12.1 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ15138.1 - 0.12 12.3 0.2 0.27 11.1 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 OAJ15138.1 - 0.25 10.0 1.4 0.55 8.9 1.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 OAJ15138.1 - 10 6.5 6.9 0.69 10.2 0.7 2.3 3 0 0 3 3 1 0 NAD(P)-binding Rossmann-like domain 4HBT_2 PF13279.6 OAJ15139.1 - 3e-07 31.0 0.0 3.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAJ15139.1 - 2.9e-05 24.3 0.0 4.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 OAJ15139.1 - 0.0024 17.2 0.1 0.0064 15.8 0.1 1.6 2 0 0 2 2 2 1 Acyl-ACP thioesterase ADH_N PF08240.12 OAJ15140.1 - 1.3e-24 86.2 2.4 2e-24 85.5 2.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ15140.1 - 3.2e-09 36.8 0.0 0.00028 20.9 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Shikimate_DH PF01488.20 OAJ15140.1 - 0.00047 20.2 0.0 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ADH_N_assoc PF13823.6 OAJ15140.1 - 0.001 18.9 1.2 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 OAJ15140.1 - 0.0048 16.3 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TMEM100 PF16311.5 OAJ15140.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 MMS1_N PF10433.9 OAJ15141.1 - 4.6e-144 480.7 0.0 7e-144 480.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAJ15141.1 - 1.1e-79 268.1 0.0 3.1e-79 266.6 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region TPR_12 PF13424.6 OAJ15143.1 - 5.9e-08 32.9 26.1 0.06 13.6 0.1 12.0 10 2 2 12 12 12 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ15143.1 - 0.0007 19.4 26.3 0.8 9.7 0.0 11.4 13 1 0 13 13 13 2 Tetratricopeptide repeat DUF4439 PF14530.6 OAJ15143.1 - 0.012 16.3 21.4 5.7 7.6 0.1 7.6 6 2 3 9 9 9 0 Domain of unknown function (DUF4439) Glyco_hydro_65m PF03632.15 OAJ15155.1 - 3.2e-43 148.0 0.5 3.5e-36 124.9 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 OAJ15155.1 - 5.1e-24 85.2 0.0 1.1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 OAJ15155.1 - 2.4e-05 24.1 0.0 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 OAJ15155.1 - 5.1e-05 23.4 0.3 0.00027 21.1 0.1 2.4 2 0 0 2 2 2 1 F5/8 type C domain DUF2152 PF10222.9 OAJ15155.1 - 0.0024 16.3 0.0 0.34 9.2 0.0 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2152) Gln-synt_N PF03951.19 OAJ15155.1 - 0.13 12.0 0.2 1.2 8.9 0.0 2.6 4 0 0 4 4 4 0 Glutamine synthetase, beta-Grasp domain DEAD PF00270.29 OAJ15156.1 - 1.1e-51 175.1 0.0 1.1e-50 171.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ15156.1 - 3.9e-31 107.7 0.0 5.9e-29 100.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ15156.1 - 1.8e-06 28.1 0.0 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ15156.1 - 0.0027 18.0 0.1 1.4 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 OAJ15156.1 - 0.0065 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain CIAPIN1 PF05093.13 OAJ15157.1 - 8.2e-32 109.7 2.0 2e-31 108.5 2.0 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAJ15157.1 - 3.9e-06 27.1 0.0 6.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus AP3D1 PF06375.11 OAJ15157.1 - 0.11 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 p450 PF00067.22 OAJ15158.1 - 1.3e-70 238.4 0.0 6e-54 183.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CsbD PF05532.12 OAJ15159.1 - 1.3e-19 69.8 16.1 2.1e-10 40.3 5.2 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 OAJ15159.1 - 0.0036 17.6 1.5 0.0049 17.2 0.9 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF1495 PF07381.11 OAJ15159.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) His_Phos_2 PF00328.22 OAJ15160.1 - 4.8e-30 105.2 0.0 6e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.25 OAJ15161.1 - 1.8e-13 50.4 0.1 2.5e-11 43.4 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15161.1 - 2.7e-08 33.7 0.1 5.6e-07 29.3 0.1 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAJ15161.1 - 0.0017 18.3 0.2 0.0024 17.8 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 OAJ15161.1 - 0.0044 17.0 0.2 0.0074 16.2 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAJ15161.1 - 0.0099 16.4 1.3 0.034 14.7 0.3 2.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 OAJ15161.1 - 0.029 14.4 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 OAJ15161.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAJ15161.1 - 0.27 11.3 0.4 1 9.4 0.3 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UCH PF00443.29 OAJ15162.1 - 1.8e-55 188.3 0.0 2.5e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ15162.1 - 3.2e-30 105.8 0.0 2.8e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SUIM_assoc PF16619.5 OAJ15162.1 - 0.0023 17.9 1.6 0.014 15.4 0.1 3.0 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Peptidase_C98 PF15499.6 OAJ15162.1 - 0.0032 17.0 0.6 0.44 10.0 1.2 2.5 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1631 PF07793.11 OAJ15162.1 - 6.3 5.1 7.7 0.37 9.1 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Cu_amine_oxid PF01179.20 OAJ15163.1 - 4.6e-154 513.3 0.0 5.6e-154 513.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAJ15163.1 - 1.9e-13 50.7 0.0 4.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAJ15163.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Polysacc_deac_1 PF01522.21 OAJ15164.1 - 1.2e-22 80.1 0.0 2.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Kei1 PF08552.11 OAJ15164.1 - 0.23 11.3 2.8 0.52 10.2 2.8 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MGC-24 PF05283.11 OAJ15164.1 - 2.6 8.5 9.9 6.9 7.1 9.9 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 OAJ15164.1 - 7.9 4.9 7.1 11 4.5 7.1 1.1 1 0 0 1 1 1 0 Macoilin family Rrp15p PF07890.12 OAJ15165.1 - 2.6e-28 99.0 0.0 2.6e-28 99.0 0.0 3.1 2 2 0 2 2 1 1 Rrp15p YL1 PF05764.13 OAJ15165.1 - 8.3e-06 26.1 16.4 8.3e-06 26.1 16.4 1.6 2 0 0 2 2 1 1 YL1 nuclear protein CDC45 PF02724.14 OAJ15165.1 - 0.0063 14.9 11.3 0.0097 14.3 11.3 1.3 1 0 0 1 1 1 1 CDC45-like protein TFIIF_alpha PF05793.12 OAJ15165.1 - 0.017 13.7 21.4 0.028 13.0 21.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PI3K_1B_p101 PF10486.9 OAJ15165.1 - 0.52 8.0 5.8 0.69 7.6 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 OAJ15165.1 - 0.6 8.1 35.5 1.1 7.3 35.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OAJ15165.1 - 1 8.6 30.5 0.051 12.9 23.0 2.0 2 0 0 2 2 2 0 BUD22 TFB6 PF17110.5 OAJ15165.1 - 1.1 9.0 8.0 2.7 7.7 6.9 2.1 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 OAJ15165.1 - 2.5 7.4 27.3 5.6 6.3 27.3 1.4 1 1 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 OAJ15165.1 - 4.9 6.6 15.6 0.79 9.2 11.4 1.7 2 0 0 2 2 2 0 DNA replication and checkpoint protein LAP1C PF05609.12 OAJ15165.1 - 5.7 5.9 9.0 7.9 5.4 9.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SURF2 PF05477.11 OAJ15165.1 - 8.2 6.0 9.3 24 4.5 9.3 1.8 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RR_TM4-6 PF06459.12 OAJ15165.1 - 8.7 6.1 9.5 9 6.0 5.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S8 PF00082.22 OAJ15166.1 - 1.5e-10 40.8 4.1 1.5e-10 40.8 4.1 1.8 1 1 0 2 2 2 1 Subtilase family Porin_3 PF01459.22 OAJ15168.1 - 1.2e-69 234.8 1.1 1.4e-69 234.6 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Linker_histone PF00538.19 OAJ15169.1 - 2.6e-18 66.1 0.1 2.6e-18 66.1 0.1 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family zf-C2H2_12 PF18658.1 OAJ15169.1 - 0.25 11.0 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type DAO PF01266.24 OAJ15170.1 - 1.7e-20 74.0 0.7 2.5e-11 43.7 0.0 3.4 2 2 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ15170.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ15170.1 - 0.0014 18.8 0.2 0.0036 17.5 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ15170.1 - 0.0026 17.1 0.1 0.0052 16.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 OAJ15170.1 - 0.007 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OAJ15170.1 - 0.018 14.3 0.0 0.083 12.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAJ15170.1 - 0.034 13.7 0.6 0.065 12.8 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 OAJ15170.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 OAJ15170.1 - 0.085 12.3 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 OAJ15170.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ15170.1 - 0.21 12.2 1.2 0.39 11.3 1.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DDE_Tnp_4 PF13359.6 OAJ15183.1 - 6.8e-18 64.8 0.0 1.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 OAJ15183.1 - 0.00095 18.8 0.4 0.0021 17.7 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease VHP PF02209.19 OAJ15183.1 - 0.044 13.9 0.2 0.083 13.0 0.2 1.4 1 0 0 1 1 1 0 Villin headpiece domain HTH_23 PF13384.6 OAJ15183.1 - 0.05 13.4 0.5 0.46 10.3 0.1 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r4 PF04545.16 OAJ15183.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_36 PF13730.6 OAJ15183.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 OAJ15183.1 - 0.064 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Plant_tran PF04827.14 OAJ15183.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Plant transposon protein HTH_11 PF08279.12 OAJ15183.1 - 0.16 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 HTH domain Tim44 PF04280.15 OAJ15185.1 - 0.0047 17.0 0.0 0.56 10.3 0.0 2.4 2 1 0 2 2 2 2 Tim44-like domain MMU163 PF17119.5 OAJ15185.1 - 0.067 12.4 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Pkinase PF00069.25 OAJ15186.1 - 1.3e-54 185.4 0.0 1.8e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15186.1 - 3.8e-19 69.0 0.0 7.5e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAJ15186.1 - 0.0067 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 OAJ15186.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 OAJ15186.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family CAP PF00188.26 OAJ15188.1 - 3.3e-22 79.7 1.8 1e-21 78.0 1.8 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PGK PF00162.19 OAJ15189.1 - 1.7e-150 501.2 2.9 1.9e-150 501.1 2.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 OAJ15189.1 - 0.0062 16.5 0.6 0.054 13.5 0.0 2.6 3 0 0 3 3 3 1 PA domain NTF2 PF02136.20 OAJ15190.1 - 1.4e-32 112.8 0.2 1.6e-32 112.6 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAJ15190.1 - 0.00094 19.6 0.0 0.0011 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) ABC2_membrane PF01061.24 OAJ15192.1 - 2.2e-38 131.8 19.8 2.2e-38 131.8 19.8 2.1 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ15192.1 - 4.4e-25 88.8 0.0 7.9e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ15192.1 - 1.8e-05 24.7 0.1 0.12 12.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAJ15192.1 - 1.9e-05 23.9 23.6 4.6e-05 22.7 23.6 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 OAJ15192.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ15192.1 - 0.037 13.8 0.9 0.064 13.0 0.1 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ15192.1 - 0.049 14.2 0.0 0.09 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ15192.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Peroxin-3 PF04882.12 OAJ15192.1 - 0.069 12.1 0.4 0.13 11.2 0.4 1.3 1 0 0 1 1 1 0 Peroxin-3 AAA_22 PF13401.6 OAJ15192.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ15192.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ15192.1 - 0.12 12.3 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OAJ15192.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 OAJ15192.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ15192.1 - 0.18 12.3 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ15192.1 - 0.2 11.2 0.2 0.48 10.0 0.2 1.6 2 0 0 2 2 2 0 AAA domain TFIID_30kDa PF03540.13 OAJ15193.1 - 1.6e-05 24.8 0.3 2.3e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 OAJ15193.1 - 0.0085 16.6 1.2 0.01 16.4 1.2 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 CAP PF00188.26 OAJ15194.1 - 3.1e-21 76.5 3.5 6e-21 75.6 3.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 OAJ15195.1 - 3.5e-21 76.4 2.7 8.2e-21 75.1 2.7 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF977 PF06163.11 OAJ15195.1 - 0.2 11.6 1.9 0.39 10.7 1.9 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) TPPK_C PF12555.8 OAJ15209.1 - 1.5 8.9 3.9 0.81 9.8 0.4 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF1708 PF08101.11 OAJ15210.1 - 5.2e-16 58.8 0.7 1.8e-11 43.9 0.0 3.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1708) Ndc1_Nup PF09531.10 OAJ15210.1 - 0.0048 15.7 1.9 0.0072 15.1 1.9 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RhoGAP PF00620.27 OAJ15210.1 - 0.064 13.1 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 RhoGAP domain Rab5ip PF07019.12 OAJ15212.1 - 4.3e-15 56.1 3.8 5.4e-15 55.7 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) zf-RING_2 PF13639.6 OAJ15213.1 - 5.3e-09 36.3 5.4 3e-07 30.6 0.3 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ15213.1 - 4.7e-06 26.3 5.9 6.8e-06 25.8 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ15213.1 - 1e-05 25.3 2.3 0.00027 20.7 0.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ15213.1 - 3.8e-05 23.9 0.3 3.8e-05 23.9 0.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OAJ15213.1 - 0.00031 20.3 1.1 0.00064 19.3 1.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAJ15213.1 - 0.00064 19.5 0.4 0.00064 19.5 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ15213.1 - 0.00076 19.4 2.4 0.0028 17.6 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ15213.1 - 0.0025 17.6 3.9 0.006 16.4 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ15213.1 - 0.0088 16.1 1.4 0.0088 16.1 1.4 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 OAJ15213.1 - 0.051 13.6 0.1 0.051 13.6 0.1 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 OAJ15213.1 - 0.065 13.6 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 OAJ15213.1 - 0.079 12.7 2.7 2 8.3 0.0 2.8 2 0 0 2 2 2 0 RING-like zinc finger TMEM132D_C PF15706.5 OAJ15213.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FANCL_C PF11793.8 OAJ15213.1 - 0.63 10.2 8.0 0.6 10.3 3.4 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 OAJ15213.1 - 2.4 8.3 6.2 0.33 11.1 1.3 2.0 2 0 0 2 2 2 0 RING-variant domain Rad50_zn_hook PF04423.14 OAJ15213.1 - 4.1 7.3 4.6 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 OAJ15213.1 - 7.8 6.8 8.4 1.2 9.4 0.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_1e PF01406.19 OAJ15214.1 - 4.2e-121 404.0 0.0 6.1e-72 242.5 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAJ15214.1 - 2.7e-06 26.4 0.8 0.0012 17.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ15214.1 - 0.00028 19.3 0.1 0.0036 15.6 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 OAJ15214.1 - 0.00046 20.6 2.1 0.001 19.5 0.0 2.7 3 0 0 3 3 3 1 DALR domain tRNA-synt_1c PF00749.21 OAJ15214.1 - 0.0013 17.7 0.2 0.25 10.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 OAJ15214.1 - 0.14 11.1 0.1 8.4 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF3991 PF13154.6 OAJ15214.1 - 0.16 12.3 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) PGAP1 PF07819.13 OAJ15215.1 - 3.8e-63 213.3 0.0 6e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 OAJ15215.1 - 0.022 14.3 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAJ15215.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Mito_carr PF00153.27 OAJ15216.1 - 3.7e-57 190.3 1.6 2.5e-17 62.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.23 OAJ15217.1 - 3.4e-74 249.7 0.0 8.3e-74 248.4 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAJ15217.1 - 1.3e-38 131.5 0.3 1.3e-38 131.5 0.3 3.2 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 OAJ15217.1 - 3.1e-31 108.4 6.0 3.1e-31 108.4 6.0 3.5 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 OAJ15217.1 - 7.2e-19 68.2 0.0 1.8e-17 63.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ15217.1 - 6.6e-11 42.5 0.1 5.4e-10 39.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ15217.1 - 1.9e-07 30.5 0.0 5.9e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 OAJ15217.1 - 8.5e-06 25.9 0.0 0.024 14.8 0.0 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 OAJ15217.1 - 2.6e-05 24.1 0.0 8.7e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HWE_HK PF07536.14 OAJ15217.1 - 0.0016 19.1 0.9 0.21 12.3 0.0 3.0 2 0 0 2 2 2 1 HWE histidine kinase AAA_14 PF13173.6 OAJ15217.1 - 0.015 15.3 1.9 0.026 14.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ15217.1 - 0.14 12.4 2.7 0.39 11.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain Aldedh PF00171.22 OAJ15218.1 - 3.4e-131 437.9 0.5 4.1e-131 437.7 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAJ15218.1 - 0.16 11.0 0.5 0.23 10.4 0.1 1.4 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Histone PF00125.24 OAJ15219.1 - 3.3e-44 150.4 1.2 7.2e-44 149.3 1.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ15219.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ15219.1 - 0.085 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein Prefoldin PF02996.17 OAJ15220.1 - 1.6e-28 99.0 0.0 2e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Cortex-I_coil PF09304.10 OAJ15220.1 - 0.023 14.9 2.4 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.11 OAJ15220.1 - 0.044 14.3 0.5 2.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal NADH_4Fe-4S PF10589.9 OAJ15220.1 - 0.094 12.8 0.4 9.7 6.3 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region CBFD_NFYB_HMF PF00808.23 OAJ15221.1 - 1.8e-20 73.0 0.0 3.3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ15221.1 - 0.00066 20.0 2.3 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ15221.1 - 0.037 14.2 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CNDH2_C PF16858.5 OAJ15221.1 - 0.063 13.1 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MCM PF00493.23 OAJ15222.1 - 4.5e-105 349.7 0.0 6.7e-105 349.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ15222.1 - 6.7e-34 116.4 0.0 1.3e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ15222.1 - 9.6e-29 99.6 1.0 2.5e-28 98.3 1.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ15222.1 - 1.7e-13 51.1 0.0 3.7e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ15222.1 - 1.8e-06 27.5 0.0 0.00047 19.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ15222.1 - 7.7e-06 26.0 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ15222.1 - 0.00011 22.0 0.0 0.0015 18.4 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ15222.1 - 0.032 14.0 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAJ15222.1 - 0.13 12.6 0.2 0.71 10.3 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Telomere_reg-2 PF10193.9 OAJ15223.1 - 1.5e-26 93.0 0.0 9.3e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein Ribosomal_L28e PF01778.17 OAJ15224.1 - 3.6e-19 69.6 0.0 4.1e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Citrate_ly_lig PF08218.11 OAJ15224.1 - 0.0074 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Citrate lyase ligase C-terminal domain BLM10_mid PF16507.5 OAJ15238.1 - 4.2e-119 398.6 0.0 6e-119 398.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAJ15238.1 - 7.5e-19 67.4 0.8 1e-16 60.6 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT_EZ PF13513.6 OAJ15238.1 - 0.0035 17.8 0.1 0.29 11.7 0.0 3.3 2 0 0 2 2 2 1 HEAT-like repeat zf_C2H2_6 PF18450.1 OAJ15238.1 - 0.055 13.2 0.4 0.14 11.9 0.4 1.6 1 0 0 1 1 1 0 Zinc Finger domain HEAT PF02985.22 OAJ15238.1 - 0.063 13.6 0.2 11 6.5 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OAJ15238.1 - 0.23 11.9 0.0 0.23 11.9 0.0 4.1 5 1 0 5 5 5 0 HEAT repeats DUF3316 PF11777.8 OAJ15239.1 - 2.5 8.1 5.2 3.4 7.7 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3316) TMEM154 PF15102.6 OAJ15239.1 - 9.8 6.1 7.7 16 5.4 7.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family p450 PF00067.22 OAJ15240.1 - 1.9e-45 155.5 0.0 2.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LPD13 PF18825.1 OAJ15240.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 RIFIN PF02009.16 OAJ15240.1 - 2.4 8.0 7.4 7.1 6.4 7.4 1.7 1 1 0 1 1 1 0 Rifin Vps16_C PF04840.12 OAJ15241.1 - 2.4e-69 233.8 1.7 1.6e-36 126.0 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.13 OAJ15241.1 - 4.1e-51 174.0 0.0 2.9e-20 72.4 0.0 4.2 4 0 0 4 4 4 3 Vps16, N-terminal region ANTH PF07651.16 OAJ15242.1 - 3.1e-48 164.2 0.3 5.3e-48 163.4 0.3 1.4 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAJ15242.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Vfa1 PF08432.10 OAJ15242.1 - 0.35 11.2 8.7 0.59 10.4 8.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.32 OAJ15243.1 - 7.9e-08 32.9 4.0 0.0057 17.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 OAJ15243.1 - 7.6e-06 25.7 0.1 1.8e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ15243.1 - 3.8e-05 23.5 0.1 8.7e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like HAD_2 PF13419.6 OAJ15243.1 - 0.00018 21.7 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ15243.1 - 0.0034 17.7 0.0 0.07 13.4 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 OAJ15243.1 - 0.0046 16.5 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) HSBP1 PF06825.12 OAJ15244.1 - 3.3e-14 52.5 0.4 4.5e-14 52.0 0.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Tmemb_cc2 PF10267.9 OAJ15244.1 - 0.14 11.3 0.0 0.16 11.1 0.0 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CDC50 PF03381.15 OAJ15245.1 - 6.7e-71 239.1 0.0 8.8e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PIP5K PF01504.18 OAJ15246.1 - 2.3e-38 132.0 0.0 5.4e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ACOX PF01756.19 OAJ15247.1 - 7.1e-33 113.7 0.0 1.7e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAJ15247.1 - 5.9e-19 68.8 0.0 2.6e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 OAJ15247.1 - 2.5e-08 34.3 0.0 1.4e-07 31.8 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ15247.1 - 1.5e-07 31.5 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ribosomal_L36 PF00444.18 OAJ15248.1 - 7.3e-21 74.1 8.1 1.5e-20 73.1 8.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 DUF3984 PF13136.6 OAJ15248.1 - 0.078 12.4 10.7 0.097 12.1 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Ribonuc_red_lgN PF00317.21 OAJ15248.1 - 0.12 12.4 0.2 1.6 8.8 0.0 2.1 1 1 1 2 2 2 0 Ribonucleotide reductase, all-alpha domain adh_short_C2 PF13561.6 OAJ15249.1 - 1.9e-56 191.3 1.2 2.6e-56 190.8 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ15249.1 - 8.4e-45 152.6 0.2 8.4e-45 152.6 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAJ15249.1 - 1.3e-11 44.7 1.5 4e-11 43.1 0.6 2.1 1 1 1 2 2 2 1 KR domain SbcD_C PF12320.8 OAJ15249.1 - 0.0076 16.5 0.4 0.033 14.5 0.2 1.9 1 1 1 2 2 2 1 Type 5 capsule protein repressor C-terminal domain JAKMIP_CC3 PF16034.5 OAJ15249.1 - 0.024 14.6 0.1 0.036 14.0 0.1 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain RNase_PH PF01138.21 OAJ15259.1 - 2e-06 28.4 0.0 4.3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ15259.1 - 8.6e-06 25.7 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Shadoo PF14999.6 OAJ15259.1 - 0.035 14.2 1.9 0.066 13.3 1.9 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DEC-1_N PF04625.13 OAJ15261.1 - 3.2 6.7 13.0 3.3 6.6 13.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Lipase_GDSL PF00657.22 OAJ15263.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAJ15263.1 - 0.032 14.6 0.8 0.19 12.1 0.7 2.0 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF3984 PF13136.6 OAJ15266.1 - 0.032 13.6 7.2 0.048 13.1 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) CDPS PF16715.5 OAJ15266.1 - 0.076 12.7 1.9 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Cyclodipeptide synthase DUF728 PF05304.12 OAJ15266.1 - 0.12 12.2 3.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Pinin_SDK_memA PF04696.13 OAJ15266.1 - 0.3 11.2 14.2 1.7 8.7 3.7 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region OmpH PF03938.14 OAJ15266.1 - 1 9.7 9.7 0.3 11.4 1.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Btz PF09405.10 OAJ15267.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 4.7 4 1 0 4 4 4 2 CASC3/Barentsz eIF4AIII binding DNA_pol_phi PF04931.13 OAJ15267.1 - 7.8 4.5 18.9 12 3.8 18.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pex2_Pex12 PF04757.14 OAJ15268.1 - 9.4e-29 100.6 5.0 1.3e-28 100.1 5.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OAJ15268.1 - 1.2e-09 38.4 8.1 1.7e-09 37.8 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ15268.1 - 1.9e-09 37.2 4.8 2.8e-09 36.7 4.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ15268.1 - 2.1e-08 34.0 6.0 3.1e-08 33.4 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ15268.1 - 6.1e-08 32.4 6.7 1.1e-07 31.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15268.1 - 1.2e-07 31.5 5.1 1.9e-07 30.8 5.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ15268.1 - 2.5e-07 30.9 5.3 4.3e-07 30.1 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAJ15268.1 - 4.4e-07 29.8 2.6 1.1e-06 28.6 2.2 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ15268.1 - 5.7e-07 29.3 6.1 8.9e-07 28.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ15268.1 - 0.00076 19.6 3.1 0.00076 19.6 3.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAJ15268.1 - 0.02 14.7 6.9 0.032 14.0 6.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 OAJ15268.1 - 0.022 14.5 3.4 0.044 13.5 1.7 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 OAJ15268.1 - 0.043 13.9 4.4 0.081 13.1 4.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 OAJ15268.1 - 0.046 13.8 2.5 0.082 13.0 2.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 OAJ15268.1 - 0.078 12.9 2.3 0.14 12.1 2.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 OAJ15268.1 - 0.11 12.8 3.9 0.22 11.8 3.9 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Baculo_IE-1 PF05290.11 OAJ15268.1 - 0.19 11.7 0.6 0.35 10.8 0.6 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 OAJ15271.1 - 8.5e-08 31.9 9.4 8.5e-08 31.9 9.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ15271.1 - 5.7e-07 29.3 3.5 1.8e-06 27.7 3.5 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 OAJ15271.1 - 9.5e-07 28.6 12.6 1.5e-06 28.0 9.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ15271.1 - 3e-06 27.1 15.0 4.8e-06 26.5 9.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAJ15271.1 - 6.1e-06 26.3 9.2 6.1e-06 26.3 9.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ15271.1 - 2.5e-05 24.1 14.1 3.6e-05 23.6 10.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ15271.1 - 4e-05 23.4 10.9 0.00045 20.0 8.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ15271.1 - 4.6e-05 23.4 4.5 0.00011 22.2 2.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAJ15271.1 - 0.00017 21.8 15.5 0.00028 21.1 9.9 2.3 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.27 OAJ15271.1 - 0.0022 17.7 0.4 0.11 12.3 0.0 2.8 2 0 0 2 2 2 1 SAP domain ISG65-75 PF11727.8 OAJ15271.1 - 0.0037 16.6 2.9 0.29 10.3 0.1 2.6 2 1 0 2 2 2 2 Invariant surface glycoprotein Prok-RING_4 PF14447.6 OAJ15271.1 - 0.0067 16.3 10.7 1.4 8.8 7.4 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-Nse PF11789.8 OAJ15271.1 - 0.01 15.6 4.7 0.01 15.6 4.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.6 OAJ15271.1 - 0.037 13.8 0.4 12 5.7 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-rbx1 PF12678.7 OAJ15271.1 - 0.097 13.0 8.3 0.092 13.0 5.4 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain U-box PF04564.15 OAJ15271.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 U-box domain MOR2-PAG1_mid PF14228.6 OAJ15271.1 - 0.14 9.7 1.5 0.21 9.2 1.5 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region zf-C2H2_4 PF13894.6 OAJ15271.1 - 0.38 11.7 0.1 0.38 11.7 0.1 4.0 3 1 1 4 4 2 0 C2H2-type zinc finger zf-RING_4 PF14570.6 OAJ15271.1 - 0.49 10.2 9.7 0.93 9.3 7.1 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OAJ15271.1 - 0.77 9.9 5.9 1.6 8.9 5.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF908 PF06012.12 OAJ15271.1 - 1.5 8.1 6.6 0.11 11.9 1.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) TRAF6_Z2 PF18048.1 OAJ15271.1 - 1.9 8.7 7.0 0.67 10.1 0.1 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-WRNIP1_ubi PF18279.1 OAJ15271.1 - 2.3 9.1 0.0 2.3 9.1 0.0 2.9 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FYVE PF01363.21 OAJ15271.1 - 2.3 8.4 10.0 16 5.7 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger Peptidase_M16 PF00675.20 OAJ15287.1 - 5e-16 59.0 0.5 1.6e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ15287.1 - 7.7e-07 29.3 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF5362 PF17319.2 OAJ15287.1 - 0.083 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PhoLip_ATPase_C PF16212.5 OAJ15288.1 - 1.6e-71 241.0 26.9 1.6e-71 241.0 26.9 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ15288.1 - 2.8e-19 68.6 3.7 2.8e-19 68.6 3.7 2.8 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ15288.1 - 6.3e-12 45.4 0.0 4.1e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ15288.1 - 2.9e-11 44.1 0.2 2.5e-05 24.7 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ15288.1 - 3.5e-05 23.4 0.0 3.5e-05 23.4 0.0 2.9 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ15288.1 - 0.00065 19.5 0.8 0.0089 15.8 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 OAJ15289.1 - 0.00086 20.1 0.7 0.64 11.0 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAJ15289.1 - 0.031 13.0 0.2 0.058 12.1 0.2 1.3 1 0 0 1 1 1 0 Nup133 N terminal like Acyltransferase PF01553.21 OAJ15290.1 - 1.6e-10 40.7 0.0 0.00016 21.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Sugar_tr PF00083.24 OAJ15291.1 - 4.3e-42 144.5 24.3 2e-24 86.3 5.3 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ15291.1 - 2.1e-16 59.8 34.3 2.2e-09 36.7 12.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ15291.1 - 3 6.0 8.9 2.5 6.3 1.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family tRNA_Me_trans PF03054.16 OAJ15292.1 - 9e-92 307.6 0.0 4.9e-80 269.0 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 OAJ15292.1 - 3.6e-05 23.0 0.0 0.0019 17.4 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 OAJ15292.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) VHS PF00790.19 OAJ15293.1 - 2.2e-20 72.9 0.0 4.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAJ15293.1 - 1.3e-05 25.4 2.4 6.2e-05 23.2 1.3 2.4 2 0 0 2 2 2 1 GAT domain DUF1682 PF07946.14 OAJ15293.1 - 1.3 8.1 18.5 3.1 6.9 18.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Tfb4 PF03850.14 OAJ15293.1 - 2.4 7.6 5.6 4.5 6.7 5.3 1.5 1 1 0 1 1 1 0 Transcription factor Tfb4 Pyr_redox_dim PF02852.22 OAJ15294.1 - 0.062 13.6 0.0 0.26 11.6 0.0 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Glyco_transf_20 PF00982.21 OAJ15295.1 - 5.2e-144 480.5 0.0 8.6e-144 479.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ15295.1 - 1.3e-21 76.8 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Myc_N PF01056.18 OAJ15297.1 - 0.017 15.0 0.8 0.017 15.0 0.8 1.6 2 0 0 2 2 2 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 OAJ15297.1 - 0.15 12.3 5.4 0.11 12.7 1.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 OAJ15297.1 - 0.68 10.4 7.1 1.3 9.4 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ15297.1 - 2.1 8.8 7.2 0.76 10.2 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 OAJ15297.1 - 2.2 7.9 8.9 0.051 13.3 1.0 2.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein TPR_1 PF00515.28 OAJ15298.1 - 5.5e-24 82.9 2.1 5.8e-09 35.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ15298.1 - 1.2e-17 63.2 5.2 1.9e-07 30.6 2.4 3.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 OAJ15298.1 - 7.9e-16 56.8 12.2 4e-07 29.6 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ15298.1 - 7.9e-12 44.7 0.2 2.1e-06 27.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ15298.1 - 1.2e-11 43.8 1.6 5e-05 23.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ15298.1 - 1.9e-10 40.7 7.2 0.00011 22.8 0.1 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ15298.1 - 2e-07 31.4 2.0 0.00017 22.1 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ15298.1 - 1.5e-06 27.8 1.0 0.0017 18.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ15298.1 - 2.1e-06 27.4 2.0 0.0012 18.7 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ15298.1 - 2.8e-06 27.9 4.2 0.00092 19.8 0.3 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15298.1 - 3.3e-05 24.1 1.4 3.3e-05 24.1 1.4 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ15298.1 - 0.00013 22.0 4.7 0.00028 21.0 0.2 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 OAJ15298.1 - 0.0051 16.7 8.3 0.0075 16.2 1.5 2.7 1 1 1 2 2 2 1 STI1 domain NARP1 PF12569.8 OAJ15298.1 - 0.021 13.7 0.7 0.15 10.9 0.4 1.9 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 RPN7 PF10602.9 OAJ15298.1 - 0.066 12.9 0.5 0.17 11.6 0.1 1.8 1 1 1 2 2 2 0 26S proteasome subunit RPN7 BTAD PF03704.17 OAJ15298.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.6 3 0 0 3 3 2 0 Bacterial transcriptional activator domain MIT PF04212.18 OAJ15298.1 - 0.57 10.3 5.2 34 4.6 1.4 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 OAJ15298.1 - 2.7 8.8 9.2 8.4 7.3 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Ras PF00071.22 OAJ15299.1 - 3.9e-57 192.4 0.1 4.8e-57 192.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ15299.1 - 5.5e-35 120.2 0.1 7.8e-35 119.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ15299.1 - 2.8e-16 59.5 0.0 2.6e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ15299.1 - 7.2e-07 28.8 0.0 9.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ15299.1 - 3.5e-05 23.4 0.0 4.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ15299.1 - 0.0002 21.4 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ15299.1 - 0.0028 18.1 0.5 0.0057 17.0 0.4 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ15299.1 - 0.019 14.9 0.1 7.9 6.4 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase Sporozoite_P67 PF05642.11 OAJ15299.1 - 3.1 5.8 11.0 0.31 9.1 2.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CRCB PF02537.15 OAJ15300.1 - 0.11 12.8 0.2 0.31 11.4 0.2 1.8 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) PBP1_TM PF14812.6 OAJ15311.1 - 3.3 8.2 15.1 0.2 12.1 4.0 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.16 OAJ15313.1 - 4.3e-33 114.7 11.4 4.3e-33 114.7 11.4 1.4 2 0 0 2 2 2 1 TLC domain LRR_8 PF13855.6 OAJ15314.1 - 2.7e-10 39.8 2.4 5.1e-10 39.0 2.4 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAJ15314.1 - 9.5e-09 35.4 6.7 2.8e-06 27.5 0.2 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ15314.1 - 0.0038 17.6 7.0 3 8.7 0.2 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat DAGAT PF03982.13 OAJ15315.1 - 2.6e-95 318.8 0.0 1e-50 172.3 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase CH PF00307.31 OAJ15318.1 - 7.3e-79 261.0 0.0 2.1e-20 72.9 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OAJ15318.1 - 2.8e-06 27.1 0.0 0.66 9.9 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 OAJ15318.1 - 1.1e-05 25.7 1.8 1.4e-05 25.5 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 OAJ15318.1 - 0.0045 16.8 0.1 2 8.5 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 OAJ15318.1 - 0.037 13.6 0.4 10 5.9 0.0 3.6 3 0 0 3 3 3 0 EF hand CH_2 PF06294.11 OAJ15318.1 - 0.06 13.5 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein NAD_binding_1 PF00175.21 OAJ15319.1 - 8.3e-07 29.6 0.0 0.00049 20.7 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAJ15319.1 - 5e-06 26.8 0.0 3e-05 24.3 0.0 2.3 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAJ15319.1 - 0.016 15.4 0.0 0.071 13.2 0.0 2.0 1 1 0 1 1 1 0 Ferric reductase NAD binding domain OAD_gamma PF04277.13 OAJ15320.1 - 0.32 11.6 0.5 0.66 10.6 0.5 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Urm1 PF09138.11 OAJ15321.1 - 7.2e-31 106.4 0.0 1.2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.22 OAJ15321.1 - 3.7e-30 105.1 1.4 3.1e-28 98.8 0.9 2.7 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 OAJ15322.1 - 7.4e-28 97.6 0.0 1.1e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15322.1 - 2.2e-13 50.1 0.0 6.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ15322.1 - 0.018 14.4 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CN_hydrolase PF00795.22 OAJ15323.1 - 7.5e-49 166.4 0.1 8.6e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GIT_SHD PF08518.11 OAJ15332.1 - 1.8e-24 85.1 8.0 1.4e-13 50.2 1.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 OAJ15332.1 - 0.0074 16.4 7.1 0.019 15.1 0.0 3.6 3 1 1 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term LMBR1 PF04791.16 OAJ15332.1 - 0.037 13.0 4.7 0.062 12.2 4.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CHASE7 PF17151.4 OAJ15332.1 - 0.041 13.5 6.1 0.047 13.3 4.7 1.8 2 0 0 2 2 2 0 Periplasmic sensor domain DUF2333 PF10095.9 OAJ15332.1 - 0.26 10.3 4.8 0.64 9.0 4.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) F-box PF00646.33 OAJ15333.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAJ15333.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like AT_hook PF02178.19 OAJ15333.1 - 3 8.0 16.5 1.8 8.7 7.9 3.5 2 0 0 2 2 2 0 AT hook motif FKBP_C PF00254.28 OAJ15334.1 - 2e-34 117.7 0.6 6.6e-34 116.1 0.0 2.0 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.18 OAJ15334.1 - 2.3e-10 40.7 19.6 2.8e-10 40.4 19.6 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 OAJ15334.1 - 1.2e-05 25.7 31.1 0.00082 19.9 5.1 3.3 1 1 2 3 3 3 2 YtxH-like protein DUF883 PF05957.13 OAJ15334.1 - 2.5e-05 24.8 23.4 0.024 15.2 2.6 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.11 OAJ15334.1 - 0.00067 19.8 26.9 0.0054 16.8 25.9 2.1 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Synuclein PF01387.17 OAJ15334.1 - 0.0017 18.6 18.8 0.0017 18.6 18.8 2.5 1 1 1 2 2 1 1 Synuclein ATG_C PF09333.11 OAJ15334.1 - 0.08 13.3 0.5 0.08 13.3 0.5 2.8 1 1 1 2 2 2 0 Autophagy-related protein C terminal domain Prominin PF05478.11 OAJ15334.1 - 0.086 10.8 4.7 0.1 10.5 4.7 1.1 1 0 0 1 1 1 0 Prominin Mitofilin PF09731.9 OAJ15334.1 - 0.14 11.0 24.3 0.17 10.7 24.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSP9_HSP12 PF04119.12 OAJ15334.1 - 0.15 12.4 15.8 1.1 9.6 0.9 4.2 1 1 3 4 4 4 0 Heat shock protein 9/12 HisKA_3 PF07730.13 OAJ15334.1 - 0.17 12.5 10.6 7.8 7.1 2.1 3.8 1 1 3 4 4 4 0 Histidine kinase DUF842 PF05811.13 OAJ15334.1 - 0.25 11.0 8.3 1 9.1 8.4 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Minor_capsid_3 PF12691.7 OAJ15334.1 - 0.29 11.5 1.5 6.4 7.2 0.4 2.3 1 1 1 2 2 2 0 Minor capsid protein from bacteriophage Borrelia_P83 PF05262.11 OAJ15334.1 - 0.55 8.7 27.1 0.75 8.2 27.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Phasin_2 PF09361.10 OAJ15334.1 - 0.72 10.2 22.6 0.31 11.3 14.1 2.4 1 1 1 2 2 2 0 Phasin protein Activator-TraM PF11657.8 OAJ15334.1 - 2.2 8.1 21.3 2.1 8.2 7.8 2.6 1 1 1 2 2 2 0 Transcriptional activator TraM DUF885 PF05960.11 OAJ15334.1 - 2.7 7.5 11.1 3.8 7.0 11.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) PIN_8 PF18476.1 OAJ15334.1 - 4.3 7.1 13.9 69 3.2 13.9 2.2 1 1 0 1 1 1 0 PIN like domain DUF1451 PF07295.11 OAJ15334.1 - 6.5 6.8 12.6 13 5.8 10.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain FAD_binding_4 PF01565.23 OAJ15335.1 - 1.5e-13 50.7 0.2 3.4e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.12 OAJ15335.1 - 0.00019 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_C2 PF00648.21 OAJ15336.1 - 4.2e-23 81.8 0.0 7.3e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAJ15336.1 - 4e-18 66.0 0.0 2.9e-09 37.3 0.0 3.4 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 OAJ15336.1 - 0.91 9.6 2.4 7.3 6.7 2.4 2.2 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Myb_Cef PF11831.8 OAJ15337.1 - 1.5e-56 191.7 0.2 1.5e-56 191.7 0.2 3.7 4 1 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAJ15337.1 - 3e-23 81.7 4.5 4.2e-11 42.9 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ15337.1 - 8.9e-20 70.7 6.9 4.6e-13 49.2 3.4 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain VAPB_antitox PF02697.14 OAJ15337.1 - 0.016 15.9 1.7 0.16 12.8 1.7 2.8 1 0 0 1 1 1 0 Putative antitoxin Rap1_C PF11626.8 OAJ15337.1 - 0.18 11.9 1.3 2.2 8.4 0.1 3.0 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain GDC-P PF02347.16 OAJ15339.1 - 0.089 11.6 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein MFS_1 PF07690.16 OAJ15340.1 - 4.6e-16 58.7 46.6 4.6e-16 58.7 46.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF5368 PF17336.2 OAJ15340.1 - 9.3 6.5 12.0 0.75 10.0 5.7 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5368) DRIM PF07539.12 OAJ15341.1 - 1e-158 529.5 5.7 1e-158 529.5 5.7 4.2 4 1 0 4 4 4 2 Down-regulated in metastasis Telomere_reg-2 PF10193.9 OAJ15341.1 - 0.007 16.8 0.3 1.2 9.6 0.1 4.1 3 0 0 3 3 3 1 Telomere length regulation protein DUF3361 PF11841.8 OAJ15341.1 - 0.009 16.0 0.8 0.009 16.0 0.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) DNA_pol_phi PF04931.13 OAJ15341.1 - 1.1 7.2 34.9 0.87 7.6 21.9 4.0 4 0 0 4 4 4 0 DNA polymerase phi G-alpha PF00503.20 OAJ15342.1 - 6.5e-113 377.5 0.1 1.2e-112 376.6 0.1 1.5 1 0 0 1 1 1 1 G-protein alpha subunit UvdE PF03851.14 OAJ15342.1 - 3.7e-91 305.2 0.0 5.7e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE Arf PF00025.21 OAJ15342.1 - 1e-13 51.1 0.2 5.5e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ15342.1 - 0.00092 18.6 0.1 0.59 9.5 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ15342.1 - 0.054 13.7 0.1 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DTHCT PF08070.11 OAJ15342.1 - 6.4 7.6 24.5 1.7 9.4 15.9 3.1 2 0 0 2 2 2 0 DTHCT (NUC029) region DIM1 PF02966.16 OAJ15343.1 - 1.5e-65 218.9 0.1 1.7e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAJ15343.1 - 0.00025 21.0 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 OAJ15343.1 - 0.061 13.3 0.1 0.069 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Thioredoxin_7 PF13899.6 OAJ15343.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like ADH_zinc_N_2 PF13602.6 OAJ15352.1 - 6.6e-19 69.3 0.0 1.6e-18 68.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ15352.1 - 8.9e-14 51.6 0.4 1.7e-13 50.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ15352.1 - 1e-10 41.5 0.5 1.4e-07 31.4 0.2 3.5 2 2 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ15352.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.2 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase Ribosomal_L14e PF01929.17 OAJ15353.1 - 1.5e-26 92.7 1.1 2.1e-26 92.2 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAJ15353.1 - 0.028 14.4 0.0 0.028 14.4 0.0 1.8 2 0 0 2 2 2 0 KOW motif HALZ PF02183.18 OAJ15356.1 - 2.8e-05 24.2 2.2 4.4e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 Homeobox associated leucine zipper YabA PF06156.13 OAJ15356.1 - 0.039 14.6 1.6 0.087 13.5 1.5 1.7 1 1 0 1 1 1 0 Initiation control protein YabA Macoilin PF09726.9 OAJ15356.1 - 0.21 10.1 5.9 0.23 10.0 5.9 1.0 1 0 0 1 1 1 0 Macoilin family NRBF2 PF08961.10 OAJ15356.1 - 1 8.9 10.2 0.051 13.2 1.1 2.4 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Retrotrans_gag PF03732.17 OAJ15357.1 - 0.35 11.2 2.0 3.1 8.1 0.1 2.6 3 0 0 3 3 3 0 Retrotransposon gag protein Med3 PF11593.8 OAJ15357.1 - 1.3 8.2 5.1 2.5 7.2 5.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L44 PF00935.19 OAJ15359.1 - 3.3e-35 120.4 12.8 4.9e-35 119.9 12.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 OAJ15359.1 - 0.045 14.1 0.4 0.088 13.1 0.4 1.4 1 0 0 1 1 1 0 Cathelicidin BSD PF03909.17 OAJ15360.1 - 1.1e-17 63.8 1.4 3.4e-14 52.6 0.1 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OAJ15360.1 - 7.2e-09 35.9 0.0 1.5e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Pinin_SDK_N PF04697.13 OAJ15360.1 - 0.26 11.9 10.0 0.18 12.4 4.8 2.9 2 0 0 2 2 2 0 pinin/SDK conserved region Laminin_I PF06008.14 OAJ15361.1 - 0.26 11.0 5.2 0.054 13.2 1.1 1.8 2 0 0 2 2 2 0 Laminin Domain I Brr6_like_C_C PF10104.9 OAJ15362.1 - 0.00065 19.5 0.8 0.0013 18.5 0.6 1.6 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain HALZ PF02183.18 OAJ15363.1 - 0.00011 22.4 0.4 0.00011 22.4 0.4 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper NRBF2 PF08961.10 OAJ15363.1 - 0.05 13.2 1.0 0.05 13.2 1.0 1.9 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2406 PF10295.9 OAJ15363.1 - 0.066 13.9 1.3 0.14 12.9 1.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein (DUF2406) DivIC PF04977.15 OAJ15363.1 - 7.6 6.4 6.6 5.5 6.8 3.9 2.0 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 OAJ15364.1 - 0.0035 17.5 0.1 0.0057 16.9 0.1 1.3 1 0 0 1 1 1 1 Homeobox associated leucine zipper NRBF2 PF08961.10 OAJ15364.1 - 0.058 13.0 0.2 0.091 12.4 0.2 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Rab3-GTPase_cat PF13890.6 OAJ15364.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit RT_RNaseH_2 PF17919.1 OAJ15365.1 - 2.7e-20 72.3 0.0 4.3e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ15365.1 - 9.3e-16 58.0 0.0 2.5e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ15365.1 - 7.6e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ15365.1 - 2.7e-10 40.5 0.1 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ15365.1 - 8.9e-05 23.1 0.0 0.00031 21.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ15365.1 - 0.0073 16.8 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_C48 PF02902.19 OAJ15366.1 - 0.024 14.5 0.0 6.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain HALZ PF02183.18 OAJ15368.1 - 3.6e-05 23.9 0.9 3.6e-05 23.9 0.9 2.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.5 OAJ15368.1 - 0.0062 17.1 6.9 0.0062 17.1 6.9 1.8 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 OAJ15368.1 - 0.0091 16.1 1.3 0.0091 16.1 1.3 3.0 2 1 1 3 3 3 1 bZIP transcription factor NRBF2 PF08961.10 OAJ15368.1 - 0.011 15.4 2.0 0.011 15.4 2.0 2.4 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator KfrA_N PF11740.8 OAJ15368.1 - 0.022 15.4 3.6 0.033 14.8 3.3 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Cortex-I_coil PF09304.10 OAJ15368.1 - 0.068 13.4 8.1 0.17 12.1 8.1 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil YabA PF06156.13 OAJ15368.1 - 0.095 13.4 9.3 0.031 14.9 4.3 2.5 2 1 0 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 OAJ15368.1 - 0.1 11.5 10.5 0.11 11.3 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) KASH_CCD PF14662.6 OAJ15368.1 - 0.15 11.9 9.7 0.021 14.6 5.6 1.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Macoilin PF09726.9 OAJ15368.1 - 0.16 10.5 10.7 0.17 10.4 10.7 1.0 1 0 0 1 1 1 0 Macoilin family TMF_TATA_bd PF12325.8 OAJ15368.1 - 0.19 11.9 8.9 0.022 15.0 4.5 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 OAJ15368.1 - 0.49 10.7 6.8 0.39 11.1 5.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 OAJ15368.1 - 0.61 10.2 7.6 0.89 9.6 7.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OAJ15368.1 - 0.93 10.0 10.1 1.4 9.5 10.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 OAJ15368.1 - 1.2 9.6 12.4 0.56 10.7 8.0 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DUF4337 PF14235.6 OAJ15368.1 - 6.6 6.8 9.0 0.46 10.6 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF5381 PF17353.2 OAJ15381.1 - 3.7 7.3 5.5 10 5.8 5.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Ank_2 PF12796.7 OAJ15382.1 - 2.2e-32 111.5 0.2 9.7e-11 42.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 OAJ15382.1 - 3e-25 90.0 4.8 6.8e-17 62.5 0.2 4.3 3 2 0 3 3 3 2 SPX domain Ank_4 PF13637.6 OAJ15382.1 - 7e-25 87.1 2.9 5.8e-09 36.3 0.1 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ15382.1 - 2.8e-24 84.9 9.8 1e-07 32.1 0.2 7.5 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 OAJ15382.1 - 9.4e-20 70.1 5.3 1.4e-05 25.3 0.0 7.2 6 1 1 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 OAJ15382.1 - 1.4e-19 68.1 3.6 0.0014 19.0 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat GDPD PF03009.17 OAJ15382.1 - 2.1e-14 53.9 0.0 4.2e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MCM2_N PF12619.8 OAJ15382.1 - 1.7 8.9 4.0 4 7.7 4.0 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Pro-kuma_activ PF09286.11 OAJ15383.1 - 6.8e-19 68.6 0.0 1.3e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ15383.1 - 3.5e-08 33.1 4.7 3.5e-08 33.1 4.7 2.0 2 0 0 2 2 2 1 Subtilase family WAC_Acf1_DNA_bd PF10537.9 OAJ15384.1 - 4.9e-33 113.7 0.0 1.5e-32 112.1 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAJ15384.1 - 2.7e-27 95.1 0.2 2.7e-27 95.1 0.2 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAJ15384.1 - 4.5e-13 49.3 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 OAJ15384.1 - 1.4e-05 24.5 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 OrfB_Zn_ribbon PF07282.11 OAJ15385.1 - 1.4e-11 44.1 0.2 2.5e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 OAJ15385.1 - 3.8e-11 42.3 1.5 8.5e-11 41.2 1.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 OAJ15385.1 - 0.0011 19.2 1.4 0.0015 18.8 0.2 1.9 2 0 0 2 2 2 1 Probable transposase Apolipoprotein PF01442.18 OAJ15385.1 - 1.7 8.5 4.0 1.3 8.8 0.9 2.3 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain tRNA-synt_1d PF00750.19 OAJ15386.1 - 2e-96 323.0 1.9 2.7e-96 322.6 1.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAJ15386.1 - 3.7e-20 72.3 0.0 1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain POT1 PF02765.17 OAJ15386.1 - 0.0031 17.4 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Pkinase PF00069.25 OAJ15387.1 - 1.1e-70 238.0 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15387.1 - 2e-30 106.0 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ15387.1 - 0.0003 20.2 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OAJ15387.1 - 0.018 14.0 0.0 0.14 11.1 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 OAJ15387.1 - 0.049 12.7 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAJ15387.1 - 0.077 12.9 0.0 0.26 11.2 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Piwi PF02171.17 OAJ15389.1 - 4.1e-11 42.7 0.0 7.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Piwi domain AIP3 PF03915.13 OAJ15389.1 - 0.00021 20.5 2.7 0.00027 20.2 2.7 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 V_ATPase_I PF01496.19 OAJ15389.1 - 0.011 13.7 3.6 0.014 13.3 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 OAJ15389.1 - 0.064 12.8 3.5 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Pilosulin PF17499.2 OAJ15389.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Ant venom peptides PilJ PF13675.6 OAJ15389.1 - 0.14 12.2 2.2 1.5 8.9 0.6 2.3 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CAF20 PF17052.5 OAJ15389.1 - 0.8 9.9 4.4 0.67 10.1 2.3 1.9 1 1 1 2 2 2 0 Cap associated factor zf-C2H2 PF00096.26 OAJ15391.1 - 6.5e-07 29.5 2.2 0.0023 18.3 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ15391.1 - 1.8e-06 28.3 3.0 0.0048 17.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAJ15391.1 - 0.00019 21.6 2.2 0.1 12.9 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAJ15391.1 - 0.00068 19.9 5.1 0.014 15.7 0.7 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding HypA PF01155.19 OAJ15391.1 - 0.025 14.6 0.3 0.04 13.9 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ima1_N PF09779.9 OAJ15391.1 - 0.028 15.3 0.2 0.04 14.8 0.2 1.4 1 1 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_2 PF12756.7 OAJ15391.1 - 0.088 13.2 0.8 1.5 9.2 1.0 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 OAJ15391.1 - 0.12 12.3 0.2 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 OAJ15391.1 - 1.1 9.2 3.1 19 5.2 0.5 2.3 1 1 1 2 2 2 0 Rad50 zinc hook motif PyrI_C PF02748.15 OAJ15391.1 - 1.3 8.9 3.7 3.1 7.8 0.3 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_60s PF00428.19 OAJ15392.1 - 2.1e-26 92.3 5.0 2.5e-26 92.1 5.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein THOC2_N PF16134.5 OAJ15392.1 - 0.18 10.4 0.0 0.21 10.2 0.0 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Cytomega_UL84 PF06284.11 OAJ15392.1 - 0.31 9.5 0.4 0.41 9.1 0.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CRM1_C PF08767.11 OAJ15393.1 - 1.3e-122 409.0 1.2 1.3e-122 409.0 1.2 2.6 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 OAJ15393.1 - 2.3e-40 138.1 3.9 2.2e-39 134.9 1.5 3.8 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAJ15393.1 - 1.6e-33 114.2 4.0 5.2e-33 112.5 4.0 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAJ15393.1 - 3.9e-29 100.5 1.1 3.9e-29 100.5 1.1 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAJ15393.1 - 8.4e-20 70.0 2.5 2.6e-19 68.4 2.5 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAJ15393.1 - 1.4e-14 53.7 0.4 6.1e-14 51.7 0.4 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2294 PF10057.9 OAJ15393.1 - 0.7 10.0 3.7 10 6.3 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) PC_rep PF01851.22 OAJ15394.1 - 3.3e-41 137.7 22.6 1.2e-09 38.1 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat RPN2_C PF18004.1 OAJ15394.1 - 6.3e-39 133.5 3.2 6.3e-39 133.5 3.2 2.5 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 OAJ15394.1 - 7e-21 74.4 5.0 2.8e-14 53.3 0.0 4.8 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OAJ15394.1 - 1.7e-05 24.7 1.0 1 9.8 0.1 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 OAJ15394.1 - 0.00018 21.9 7.3 2.8 8.5 0.1 6.2 6 1 1 7 7 7 3 HEAT-like repeat HEAT_PBS PF03130.16 OAJ15394.1 - 0.0082 16.7 1.7 1.3e+02 3.7 0.0 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_19 PF14559.6 OAJ15394.1 - 0.086 13.4 3.7 3.6 8.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.11 OAJ15395.1 - 0.026 14.6 2.2 0.026 14.6 2.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator YkuD PF03734.14 OAJ15395.1 - 0.092 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Glyco_tran_WecB PF03808.13 OAJ15395.1 - 0.15 12.0 0.3 0.23 11.4 0.3 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family PRIMA1 PF16101.5 OAJ15395.1 - 0.21 11.7 3.8 0.42 10.6 3.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SCA7 PF08313.12 OAJ15396.1 - 9.9e-27 92.6 0.5 2.6e-26 91.3 0.5 1.7 1 0 0 1 1 1 1 SCA7, zinc-binding domain SAICAR_synt PF01259.18 OAJ15397.1 - 1.2e-92 310.1 0.0 2.3e-92 309.1 0.0 1.5 2 0 0 2 2 2 1 SAICAR synthetase Pro-kuma_activ PF09286.11 OAJ15397.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain Glyco_trans_4_4 PF13579.6 OAJ15411.1 - 1.2e-12 48.5 6.2 4.7e-12 46.6 6.2 2.0 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 OAJ15411.1 - 2.5e-07 31.2 0.0 6.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ15411.1 - 7.6e-06 26.0 3.3 1.5e-05 25.1 3.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ15411.1 - 9.7e-06 25.2 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAJ15411.1 - 0.0028 18.0 0.0 0.006 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cyt-b5 PF00173.28 OAJ15412.1 - 1.3e-12 47.7 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM70 PF14967.6 OAJ15413.1 - 0.087 12.3 0.5 0.15 11.5 0.5 1.3 1 0 0 1 1 1 0 FAM70 protein Phage_holin_3_6 PF07332.11 OAJ15413.1 - 2.9 8.0 12.8 1.3 9.1 2.3 2.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ribosomal_L37e PF01907.19 OAJ15414.1 - 9e-27 93.0 12.3 1.9e-26 92.0 12.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 OAJ15414.1 - 0.0067 16.5 0.3 0.0076 16.3 0.3 1.1 1 0 0 1 1 1 1 SelR domain HypA PF01155.19 OAJ15414.1 - 0.062 13.3 0.8 0.082 12.9 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA STT3 PF02516.14 OAJ15415.1 - 2.9e-146 488.2 30.2 7.1e-141 470.5 27.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RhoGAP PF00620.27 OAJ15417.1 - 1.1e-36 126.0 0.0 2.5e-36 124.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain TRAUB PF08164.12 OAJ15417.1 - 0.025 15.1 0.1 0.076 13.5 0.1 1.9 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal BAR_3 PF16746.5 OAJ15417.1 - 2.2 7.9 7.1 0.49 10.1 3.6 1.6 2 0 0 2 2 2 0 BAR domain of APPL family Glucan_synthase PF02364.15 OAJ15418.1 - 0 1305.2 0.0 0 1304.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAJ15418.1 - 7.4e-41 139.5 0.1 1.9e-40 138.2 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Cep57_CLD_2 PF14197.6 OAJ15419.1 - 0.0038 17.3 8.8 0.0038 17.3 8.8 8.5 5 2 2 7 7 7 3 Centrosome localisation domain of PPC89 Alg6_Alg8 PF03155.15 OAJ15420.1 - 5.6e-118 395.0 2.5 3.3e-87 293.5 0.2 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Spc7 PF08317.11 OAJ15421.1 - 0.0032 16.4 19.3 0.0032 16.4 19.3 5.8 2 1 4 6 6 6 3 Spc7 kinetochore protein DUF4250 PF14056.6 OAJ15421.1 - 1.6 8.7 3.5 37 4.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Ribosomal_L7Ae PF01248.26 OAJ15422.1 - 1.7e-18 66.1 0.0 2e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EnY2 PF10163.9 OAJ15423.1 - 2.8e-13 50.0 0.0 4.4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 RmuC PF02646.16 OAJ15423.1 - 0.062 12.4 0.7 0.083 12.0 0.7 1.1 1 0 0 1 1 1 0 RmuC family FGAR-AT_N PF18076.1 OAJ15423.1 - 0.14 12.2 0.0 9.1 6.3 0.1 2.1 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal DASH_Duo1 PF08651.10 OAJ15424.1 - 3.8e-15 55.4 0.0 5.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF4407 PF14362.6 OAJ15424.1 - 0.053 12.9 6.3 0.081 12.3 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OAJ15424.1 - 6.7 7.2 12.6 15 6.2 12.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4355 PF14265.6 OAJ15424.1 - 8.4 6.7 9.5 2.4 8.4 6.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DEAD PF00270.29 OAJ15425.1 - 5.6e-40 137.0 0.0 1.5e-39 135.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ15425.1 - 6.7e-25 87.6 0.0 2.8e-24 85.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAJ15425.1 - 1.9e-17 63.3 1.1 6.7e-17 61.5 1.1 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 OAJ15425.1 - 0.00033 20.7 0.0 0.0013 18.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IL2 PF00715.17 OAJ15438.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin 2 S4 PF01479.25 OAJ15438.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 S4 domain DHHA2 PF02833.14 OAJ15440.1 - 6.3e-18 65.3 0.0 1.4e-17 64.3 0.0 1.5 1 1 0 1 1 1 1 DHHA2 domain PhoD PF09423.10 OAJ15441.1 - 0.00043 19.4 0.0 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Dehydrin PF00257.19 OAJ15441.1 - 0.042 14.4 0.1 0.097 13.2 0.1 1.6 1 0 0 1 1 1 0 Dehydrin MAGE PF01454.19 OAJ15442.1 - 1.8e-29 103.0 0.2 1.3e-27 96.9 0.0 3.3 3 1 0 3 3 3 1 MAGE family PBP1_TM PF14812.6 OAJ15442.1 - 0.017 15.5 15.2 0.017 15.5 15.2 4.2 2 1 2 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.11 OAJ15442.1 - 1.3 8.7 39.4 0.15 11.8 27.3 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DAGAT PF03982.13 OAJ15443.1 - 1.9 7.3 3.1 10 4.9 0.6 2.1 1 1 1 2 2 2 0 Diacylglycerol acyltransferase DUF1129 PF06570.11 OAJ15444.1 - 0.96 8.9 3.8 0.54 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Arm PF00514.23 OAJ15445.1 - 5.8e-94 305.6 13.0 1.4e-12 47.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAJ15445.1 - 1.9e-23 82.7 2.9 4.8e-23 81.4 2.9 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 OAJ15445.1 - 3e-21 75.5 4.4 6.8e-09 36.1 0.0 6.1 4 2 3 7 7 7 6 HEAT-like repeat Arm_3 PF16186.5 OAJ15445.1 - 7.6e-19 67.0 0.0 3e-18 65.1 0.0 2.1 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 OAJ15445.1 - 1e-17 64.3 0.2 3.7e-06 27.2 0.0 6.7 2 1 6 8 8 8 5 HEAT repeats HEAT PF02985.22 OAJ15445.1 - 9.3e-17 59.7 1.8 0.00034 20.6 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 OAJ15445.1 - 0.00014 21.5 0.0 0.71 9.3 0.0 3.8 2 1 2 4 4 4 1 Armadillo-like HEAT_PBS PF03130.16 OAJ15445.1 - 0.00029 21.2 2.2 0.062 14.0 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 OAJ15445.1 - 0.0013 17.3 0.0 0.01 14.5 0.0 2.2 2 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 OAJ15445.1 - 0.0028 17.7 0.2 0.66 10.1 0.0 3.9 3 2 1 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 OAJ15445.1 - 0.0036 17.5 2.9 2.7 8.3 0.1 4.2 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Vps35 PF03635.17 OAJ15445.1 - 0.072 11.6 0.0 0.18 10.2 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 BING4CT PF08149.11 OAJ15446.1 - 8.4e-38 128.0 0.0 1.7e-35 120.7 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 OAJ15446.1 - 0.00035 19.7 0.0 0.00053 19.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OAJ15446.1 - 0.00046 20.9 0.6 0.037 14.9 0.0 4.1 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15446.1 - 0.0064 16.8 0.0 4.4 7.7 0.0 4.3 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain HTH_24 PF13412.6 OAJ15446.1 - 0.031 13.8 0.1 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyclin_N PF00134.23 OAJ15448.1 - 1e-36 125.5 0.1 2.2e-36 124.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ15448.1 - 1.4e-10 41.3 0.2 1.4e-10 41.3 0.2 2.3 2 2 1 3 3 3 1 Cyclin, C-terminal domain DUF3246 PF11596.8 OAJ15448.1 - 2.3 7.6 12.3 0.11 11.9 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) ArAE_2 PF10334.9 OAJ15449.1 - 1e-45 156.4 0.3 2.6e-45 155.0 0.1 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 OAJ15449.1 - 3.7e-39 135.1 2.4 3.7e-39 135.1 2.4 2.9 2 2 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAJ15449.1 - 2.2e-12 47.2 12.9 2.2e-12 47.2 12.9 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like EpuA PF11772.8 OAJ15449.1 - 0.19 11.5 1.8 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta C2 PF00168.30 OAJ15450.1 - 6.7e-23 80.9 0.0 6.7e-16 58.5 0.0 2.7 3 0 0 3 3 3 2 C2 domain DUF3425 PF11905.8 OAJ15451.1 - 8.1e-08 32.3 0.1 3.5e-07 30.2 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAJ15451.1 - 2.9e-07 30.5 5.6 2.9e-07 30.5 5.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor MPS2 PF17060.5 OAJ15451.1 - 0.22 10.8 1.1 0.34 10.1 1.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 bZIP_2 PF07716.15 OAJ15451.1 - 5.4 7.2 11.3 0.28 11.3 2.9 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Rad51 PF08423.11 OAJ15465.1 - 0.081 12.2 0.0 8.7 5.5 0.0 2.6 3 0 0 3 3 3 0 Rad51 Shisa PF13908.6 OAJ15466.1 - 1.1 9.5 4.1 1.9 8.7 4.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pneumo_att_G PF05539.11 OAJ15466.1 - 5.1 6.6 14.4 7.5 6.0 14.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ABC_tran PF00005.27 OAJ15467.1 - 5.5e-16 59.3 0.1 5.9e-07 30.1 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 OAJ15467.1 - 2.2e-08 34.3 5.3 0.003 17.4 0.1 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAJ15467.1 - 1.3e-05 25.4 0.0 0.04 14.1 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAJ15467.1 - 0.0014 19.1 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ15467.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ15467.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAJ15467.1 - 0.018 14.6 0.5 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAJ15467.1 - 0.039 13.0 0.1 0.091 11.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein SMC_N PF02463.19 OAJ15467.1 - 0.075 12.5 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 OAJ15467.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 OAJ15467.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAJ15467.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OAJ15467.1 - 0.17 11.8 0.1 0.56 10.1 0.1 1.9 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 OAJ15467.1 - 0.18 11.4 0.1 0.31 10.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAJ15467.1 - 0.19 12.1 2.0 0.29 11.5 0.3 2.4 2 1 0 2 2 2 0 AAA ATPase domain AMPKBI PF04739.15 OAJ15468.1 - 7.7e-27 93.4 0.1 2.1e-26 92.0 0.1 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 OAJ15468.1 - 1.3e-26 92.6 0.0 2.4e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 OAJ15468.1 - 0.0078 16.8 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MF_alpha_N PF05436.11 OAJ15469.1 - 0.23 11.4 0.1 0.34 10.8 0.1 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus gerPA PF10676.9 OAJ15469.1 - 0.87 9.9 6.8 12 6.2 0.6 2.9 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF DUF2125 PF09898.9 OAJ15469.1 - 2 8.0 4.6 7.8 6.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) MFS_1 PF07690.16 OAJ15472.1 - 2.2e-32 112.4 25.2 2.2e-32 112.4 25.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2976 PF11190.8 OAJ15472.1 - 0.13 12.1 1.3 18 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Chitin_synth_1 PF01644.17 OAJ15473.1 - 2.1e-66 222.9 1.3 3.5e-66 222.2 1.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OAJ15473.1 - 1.1e-22 80.4 0.0 6.8e-19 67.9 0.0 2.6 2 1 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ15473.1 - 5.1e-21 74.4 0.0 1.3e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 OAJ15473.1 - 2.6e-07 30.8 0.5 2.6e-07 30.8 0.5 2.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chromo PF00385.24 OAJ15475.1 - 3.8e-06 26.7 0.3 7.2e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HDPD PF02924.14 OAJ15475.1 - 0.019 15.1 9.4 0.11 12.5 9.4 2.4 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D zf-C2H2 PF00096.26 OAJ15476.1 - 9.2e-07 29.0 20.1 7.5e-05 23.0 1.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ15476.1 - 1.8e-05 24.9 4.3 0.00024 21.4 2.1 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ15476.1 - 0.00086 19.9 1.2 0.00086 19.9 1.2 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ15476.1 - 0.0028 17.6 0.1 0.0076 16.2 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ15476.1 - 0.0033 17.7 0.3 0.011 16.1 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ15476.1 - 0.016 15.6 3.1 0.061 13.7 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAJ15476.1 - 0.03 15.0 12.0 0.093 13.4 0.4 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 OAJ15476.1 - 0.36 10.8 2.2 0.7 9.9 1.6 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Cwf_Cwc_15 PF04889.12 OAJ15476.1 - 6 6.5 13.3 0.25 11.0 5.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NAD_synthase PF02540.17 OAJ15488.1 - 1.6e-23 83.1 0.0 6.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.22 OAJ15488.1 - 6e-22 78.2 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.16 OAJ15489.1 - 2.2e-32 112.4 29.6 2.2e-32 112.4 29.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TMEM154 PF15102.6 OAJ15490.1 - 0.0078 16.1 0.0 0.0078 16.1 0.0 2.5 1 1 1 2 2 2 1 TMEM154 protein family CcmD PF04995.14 OAJ15490.1 - 0.18 11.9 0.6 0.3 11.2 0.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) WD40 PF00400.32 OAJ15491.1 - 1.8e-34 117.2 12.9 2.7e-07 31.1 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15491.1 - 8.1e-11 42.1 0.2 0.02 15.2 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ15491.1 - 0.0011 17.6 0.0 0.3 9.6 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain SGL PF08450.12 OAJ15491.1 - 0.021 14.4 0.1 0.2 11.2 0.0 2.4 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region FA_desaturase PF00487.24 OAJ15492.1 - 5.8e-14 52.5 27.1 8.8e-14 51.9 27.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 OAJ15492.1 - 8.2e-14 51.5 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LETM1 PF07766.13 OAJ15493.1 - 1.3e-101 339.4 1.9 1.3e-101 339.4 1.9 2.3 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 OAJ15493.1 - 6.3e-05 23.3 4.8 0.0023 18.3 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 OAJ15493.1 - 0.0016 18.2 1.0 4.1 7.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OAJ15493.1 - 0.0035 17.2 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAJ15493.1 - 0.021 14.3 0.9 4.1 7.2 0.0 3.6 4 0 0 4 4 4 0 EF hand IPP-2 PF04979.14 OAJ15493.1 - 9.8 6.9 22.6 3.9 8.2 4.9 2.7 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) Rot1 PF10681.9 OAJ15494.1 - 3.6e-55 186.7 1.5 4.4e-55 186.4 1.5 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF4965 PF16335.5 OAJ15495.1 - 5.3e-60 202.0 0.0 9e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAJ15495.1 - 1.2e-58 198.3 0.0 2.6e-58 197.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAJ15495.1 - 1.3e-48 165.8 0.2 2.4e-48 164.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ15495.1 - 5.3e-05 22.7 0.8 0.0069 15.9 0.8 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ15495.1 - 0.0091 15.5 1.8 0.012 15.1 0.0 1.9 2 0 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Transposase_24 PF03004.14 OAJ15495.1 - 0.06 13.4 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Cys_Met_Meta_PP PF01053.20 OAJ15496.1 - 2.6e-152 506.8 0.0 2.9e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 OAJ15496.1 - 6.3e-11 42.2 0.1 1.4e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OAJ15496.1 - 5.1e-10 39.1 0.1 7.9e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ15496.1 - 1.2e-09 37.6 0.1 2e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ15496.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 OAJ15496.1 - 0.00035 19.2 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SepSecS PF05889.13 OAJ15496.1 - 0.067 11.9 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 OAJ15496.1 - 0.075 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein HD_3 PF13023.6 OAJ15497.1 - 4.9e-41 140.4 0.1 8.5e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAJ15497.1 - 8.3e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OAJ15497.1 - 0.00037 20.7 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 HD domain Zn_clus PF00172.18 OAJ15498.1 - 7e-08 32.5 8.0 1.2e-07 31.8 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ15498.1 - 1.8e-05 23.9 0.0 6.6e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Macoilin PF09726.9 OAJ15498.1 - 0.15 10.5 4.8 0.29 9.6 4.8 1.4 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 OAJ15498.1 - 0.22 10.3 6.4 0.42 9.3 6.4 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 OAJ15498.1 - 0.5 9.1 6.8 0.84 8.4 6.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EPL1 PF10513.9 OAJ15498.1 - 1.4 9.3 10.6 0.32 11.4 6.7 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like RR_TM4-6 PF06459.12 OAJ15498.1 - 5.9 6.6 9.4 17 5.1 9.4 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAJ15498.1 - 6.5 5.4 13.3 14 4.3 13.3 1.4 1 0 0 1 1 1 0 Presenilin MMR1 PF08505.10 OAJ15498.1 - 7.9 6.7 14.3 22 5.2 14.3 1.7 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein WD40 PF00400.32 OAJ15499.1 - 3.2e-16 59.4 11.4 1.1e-05 26.1 0.2 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15499.1 - 2.7e-15 56.5 4.5 2.7e-05 24.4 0.2 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ15499.1 - 2.8e-06 26.5 0.3 4.4e-05 22.6 0.2 2.6 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAJ15499.1 - 0.00064 19.6 0.2 0.019 14.8 0.3 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAJ15499.1 - 0.014 13.4 0.7 0.23 9.4 0.5 2.1 2 0 0 2 2 2 0 IKI3 family RVT_2 PF07727.14 OAJ15515.1 - 4.8e-39 134.4 0.0 6.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ15515.1 - 0.05 13.4 6.2 0.063 13.1 3.1 2.7 3 1 0 3 3 3 0 Reverse transcriptase-like Ribosomal_S19 PF00203.21 OAJ15517.1 - 2.2e-26 91.6 0.0 2.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 SSF PF00474.17 OAJ15518.1 - 3.1e-12 46.1 16.8 3.1e-12 46.1 16.8 2.7 2 1 0 2 2 2 1 Sodium:solute symporter family Sod_Fe_N PF00081.22 OAJ15519.1 - 4.1e-32 110.5 5.1 6.7e-32 109.8 5.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 OAJ15519.1 - 5.5e-19 68.2 0.3 2.1e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain AsmA_1 PF13109.6 OAJ15519.1 - 0.0096 15.4 0.0 0.034 13.6 0.0 1.7 1 1 1 2 2 2 1 AsmA-like C-terminal region Pkinase PF00069.25 OAJ15520.1 - 1.9e-61 207.8 0.0 4.8e-61 206.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15520.1 - 3.6e-33 114.9 0.0 1.4e-26 93.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ15520.1 - 1.1e-05 24.9 0.0 0.0021 17.4 0.0 3.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OAJ15520.1 - 0.00097 19.1 1.4 0.0043 17.0 0.0 2.7 3 1 0 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ15520.1 - 0.0037 16.4 0.0 0.0066 15.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Palm_thioest PF02089.15 OAJ15521.1 - 9.1e-74 248.3 0.0 1.2e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAJ15521.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Endomucin PF07010.12 OAJ15522.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Endomucin RELT PF12606.8 OAJ15522.1 - 1.2 8.2 5.1 49 3.0 5.1 2.2 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 RNA_pol_A_bac PF01000.26 OAJ15523.1 - 3.3e-28 98.3 0.0 5.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ15523.1 - 3.3e-19 68.1 0.0 4.6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Transglut_N PF00868.20 OAJ15526.1 - 0.055 13.8 0.5 0.16 12.3 0.3 1.8 2 0 0 2 2 2 0 Transglutaminase family Seryl_tRNA_N PF02403.22 OAJ15527.1 - 0.0062 16.7 0.0 0.0075 16.5 0.0 1.1 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Dimer_Tnp_hAT PF05699.14 OAJ15528.1 - 5e-07 29.4 0.0 1.9e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4509 PF14970.6 OAJ15528.1 - 0.076 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) NTP_transf_2 PF01909.23 OAJ15529.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pkinase PF00069.25 OAJ15539.1 - 2.3e-26 92.8 0.0 2.8e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15539.1 - 2.4e-12 46.7 0.0 3.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ15539.1 - 1.8e-08 33.6 0.0 2.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Rhodanese PF00581.20 OAJ15540.1 - 5.6e-12 46.1 0.0 1.6e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain CENP-B_dimeris PF09026.10 OAJ15540.1 - 4 7.9 8.3 11 6.5 8.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_hydro_92 PF07971.12 OAJ15541.1 - 1.8e-98 330.5 0.0 2.4e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ15541.1 - 5.6e-42 144.3 0.6 8.7e-42 143.6 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain tRNA-synt_His PF13393.6 OAJ15543.1 - 1.8e-36 126.0 0.1 6.3e-32 111.1 0.0 2.3 3 0 0 3 3 3 2 Histidyl-tRNA synthetase WHEP-TRS PF00458.20 OAJ15543.1 - 1.6e-06 28.2 0.6 1.6e-06 28.2 0.6 2.7 3 0 0 3 3 3 1 WHEP-TRS domain tRNA-synt_2b PF00587.25 OAJ15543.1 - 0.00023 21.2 0.0 0.00075 19.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 OAJ15543.1 - 0.012 15.1 0.0 0.04 13.4 0.0 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OAJ15543.1 - 0.031 13.3 0.3 0.95 8.5 0.4 2.5 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) DUF2267 PF10025.9 OAJ15544.1 - 0.1 12.9 2.0 0.23 11.8 2.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Apt1 PF10351.9 OAJ15544.1 - 0.87 8.4 4.0 0.96 8.2 4.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 OAJ15544.1 - 3.3 7.7 11.8 1.6 8.7 9.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) MAPEG PF01124.18 OAJ15545.1 - 2.1e-24 85.9 0.8 2.5e-24 85.7 0.8 1.1 1 0 0 1 1 1 1 MAPEG family Hpre_diP_synt_I PF07456.11 OAJ15545.1 - 0.042 13.9 0.1 0.1 12.6 0.1 1.7 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I DUF4203 PF13886.6 OAJ15545.1 - 0.21 11.3 3.9 0.13 12.0 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) PEP-CTERM PF07589.11 OAJ15545.1 - 8.4 6.6 8.3 0.55 10.4 2.0 2.4 3 0 0 3 3 3 0 PEP-CTERM motif p450 PF00067.22 OAJ15546.1 - 2.4e-51 174.9 0.0 4.8e-51 173.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SPOC PF07744.13 OAJ15546.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 SPOC domain Methyltransf_16 PF10294.9 OAJ15547.1 - 3.9e-10 39.7 0.0 7.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Seipin PF06775.14 OAJ15548.1 - 5.1e-42 144.2 0.0 1.8e-41 142.5 0.0 1.9 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Cwf_Cwc_15 PF04889.12 OAJ15548.1 - 4.4 7.0 25.6 3.4 7.3 11.1 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 OAJ15549.1 - 3.5e-40 135.2 13.7 7.3e-08 33.0 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15549.1 - 0.00012 22.3 0.3 8.8 6.7 0.0 4.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ15549.1 - 0.0012 17.6 0.2 2.2 6.8 0.0 3.2 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 OAJ15549.1 - 0.058 13.9 0.6 1.6 9.3 0.1 3.3 4 0 0 4 4 4 0 PQQ-like domain HA2 PF04408.23 OAJ15550.1 - 2.6e-20 72.7 0.0 4.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ15550.1 - 3.4e-18 65.8 0.0 8.6e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ15550.1 - 4e-16 59.3 0.0 7.4e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ15550.1 - 7.7e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ15550.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAJ15550.1 - 0.0028 18.0 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ15550.1 - 0.0073 16.3 0.0 0.075 13.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain LAG1-DNAbind PF09271.11 OAJ15551.1 - 9.8e-23 81.5 0.0 1.2e-21 77.9 0.0 2.5 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 OAJ15551.1 - 7.6e-14 52.2 0.0 1.9e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain IF2_N PF04760.15 OAJ15552.1 - 0.079 12.8 0.3 0.14 12.0 0.3 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region UBA_2 PF08587.11 OAJ15552.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) FAD_binding_3 PF01494.19 OAJ15563.1 - 4.7e-27 95.1 0.0 7.5e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAJ15563.1 - 2e-05 23.6 0.1 0.017 14.0 0.1 2.3 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAJ15563.1 - 0.00043 19.6 0.2 0.27 10.4 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ15563.1 - 0.00079 18.6 0.3 0.037 13.1 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ15563.1 - 0.0033 17.6 0.2 0.0084 16.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ15563.1 - 0.042 14.4 0.3 0.081 13.5 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 OAJ15564.1 - 4.9e-58 197.0 0.0 8.9e-58 196.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 OAJ15566.1 - 1.5e-43 149.1 55.6 4.4e-35 121.2 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ15566.1 - 1.5e-20 73.2 23.1 2.4e-20 72.5 23.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ15566.1 - 1.2e-16 60.7 6.4 1.2e-16 60.7 6.4 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter MRAP PF15183.6 OAJ15566.1 - 0.12 12.3 0.2 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family FAD_binding_4 PF01565.23 OAJ15567.1 - 8.9e-27 93.5 0.1 1.8e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ15567.1 - 1.6e-08 34.5 0.1 5.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like p450 PF00067.22 OAJ15568.1 - 1.3e-38 133.0 0.0 1.6e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.6 OAJ15569.1 - 4.3e-12 46.3 0.0 2e-05 24.6 0.0 2.7 2 1 0 2 2 2 2 NAD(P)H-binding Ldt_C PF17969.1 OAJ15569.1 - 0.084 13.6 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 L,D-transpeptidase C-terminal domain DUF249 PF03158.13 OAJ15569.1 - 0.098 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Multigene family 530 protein Condensation PF00668.20 OAJ15570.1 - 5.1e-29 101.3 0.0 1.1e-28 100.1 0.0 1.5 2 0 0 2 2 2 1 Condensation domain Methyltransf_2 PF00891.18 OAJ15571.1 - 8e-19 67.8 0.0 2.2e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 OAJ15571.1 - 0.037 14.7 0.0 0.09 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3135 PF11333.8 OAJ15571.1 - 0.1 12.8 0.1 21 5.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) ketoacyl-synt PF00109.26 OAJ15572.1 - 2.1e-71 240.5 0.1 5e-71 239.3 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 OAJ15572.1 - 3.4e-67 226.9 0.0 5.5e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 OAJ15572.1 - 1.1e-64 218.9 0.0 1.7e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 OAJ15572.1 - 4.5e-56 190.3 0.0 7.7e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 OAJ15572.1 - 1.2e-53 181.7 1.3 3.6e-53 180.1 0.3 2.5 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 OAJ15572.1 - 1.5e-48 165.9 0.0 3.1e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAJ15572.1 - 2.6e-40 137.1 0.7 5.3e-39 132.9 0.0 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 OAJ15572.1 - 1.5e-34 119.3 0.0 4.9e-34 117.7 0.0 2.0 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 OAJ15572.1 - 6.2e-24 84.6 0.0 1.7e-23 83.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 OAJ15572.1 - 5.4e-17 61.9 0.0 4.1e-08 33.5 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 OAJ15572.1 - 3.8e-13 49.6 0.2 1.4e-12 47.7 0.2 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ15572.1 - 1.2e-08 36.0 0.0 7.7e-08 33.5 0.0 2.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 OAJ15572.1 - 2.1e-07 30.7 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ15572.1 - 1.7e-06 27.6 0.0 4.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 OAJ15572.1 - 2.4e-05 24.1 0.2 5.2e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AMP-binding_C PF13193.6 OAJ15572.1 - 0.00018 22.4 0.0 0.0013 19.7 0.0 2.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Hydrolase PF00702.26 OAJ15572.1 - 0.0061 16.9 0.0 0.042 14.1 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thiolase_N PF00108.23 OAJ15572.1 - 0.036 13.4 0.1 0.078 12.3 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain DMA PF03474.14 OAJ15572.1 - 0.061 12.9 0.0 0.33 10.6 0.0 2.3 1 0 0 1 1 1 0 DMRTA motif Thioesterase PF00975.20 OAJ15573.1 - 1.3e-17 64.7 0.0 2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 OAJ15573.1 - 0.00013 22.6 0.0 0.0002 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ15573.1 - 0.0034 16.7 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ15573.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SMYLE_N PF18615.1 OAJ15573.1 - 0.087 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Bunya_NS-S PF01104.17 OAJ15573.1 - 0.15 11.9 1.8 0.3 10.9 1.0 1.9 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s Asp PF00026.23 OAJ15574.1 - 1.6e-18 67.2 0.1 2.8e-18 66.4 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Sas10_Utp3 PF04000.15 OAJ15586.1 - 4e-06 27.4 0.1 4e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4604 PF15377.6 OAJ15586.1 - 0.0045 17.4 24.4 0.006 17.0 24.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF1631 PF07793.11 OAJ15587.1 - 3.6 5.9 6.0 5.1 5.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Cpn60_TCP1 PF00118.24 OAJ15588.1 - 2.4e-158 527.8 1.4 2.7e-158 527.6 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 OAJ15588.1 - 0.038 13.2 0.2 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 OAJ15589.1 - 3.4e-39 134.8 38.7 2.7e-38 131.8 38.1 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ15589.1 - 3.1e-11 42.8 21.4 8.8e-11 41.3 10.3 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAJ15589.1 - 0.00044 18.8 13.8 0.0054 15.2 10.5 2.7 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CD34_antigen PF06365.12 OAJ15590.1 - 0.2 11.2 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Exo_endo_phos PF03372.23 OAJ15591.1 - 0.00038 20.1 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3328 PF11807.8 OAJ15591.1 - 0.065 13.0 0.8 0.85 9.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) VHS PF00790.19 OAJ15593.1 - 9.3e-38 129.3 0.9 1.8e-37 128.3 0.0 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAJ15593.1 - 3.9e-16 59.0 8.7 7.1e-16 58.1 8.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OAJ15593.1 - 0.00011 22.4 2.1 0.00019 21.6 2.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.20 OAJ15593.1 - 0.0015 18.3 12.8 0.043 13.7 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF3602 PF12223.8 OAJ15593.1 - 0.4 11.3 4.6 0.21 12.2 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) zf-RING_5 PF14634.6 OAJ15593.1 - 0.88 9.6 11.0 1.4 8.9 11.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain adh_short PF00106.25 OAJ15594.1 - 1.4e-24 86.6 0.0 6.9e-15 55.0 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15594.1 - 5e-16 59.0 0.0 8.5e-14 51.7 0.0 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ15594.1 - 5.1e-07 29.4 0.0 2.7e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ15594.1 - 0.0011 19.0 0.0 0.33 10.8 0.1 3.0 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 OAJ15594.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAJ15594.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 OAJ15595.1 - 1.1e-26 93.5 0.0 4.9e-25 88.1 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15595.1 - 2.4e-15 56.7 0.0 4.9e-14 52.4 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ15595.1 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAJ15595.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 OAJ15595.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 KR domain MASE2 PF05230.11 OAJ15596.1 - 0.006 16.6 0.4 0.014 15.4 0.4 1.6 1 0 0 1 1 1 1 MASE2 domain DUF155 PF02582.14 OAJ15598.1 - 1.6e-49 168.4 0.0 2.8e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TT_ORF2 PF02957.15 OAJ15598.1 - 1.5 9.8 5.8 4.1 8.3 5.2 2.1 1 1 0 1 1 1 0 TT viral ORF2 Tmemb_14 PF03647.13 OAJ15599.1 - 1.5e-18 67.3 10.1 1.8e-18 67.1 10.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 OAJ15599.1 - 0.26 11.6 3.1 0.84 10.0 3.1 1.9 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 AMP-binding PF00501.28 OAJ15600.1 - 4.3e-48 163.9 0.0 7.6e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAJ15600.1 - 2.1e-11 44.0 0.4 4.8e-11 42.8 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 OAJ15600.1 - 2.4e-09 36.5 0.2 0.0014 18.2 0.0 5.6 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 OAJ15600.1 - 0.015 16.2 2.2 0.13 13.2 0.0 3.0 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain GH3 PF03321.13 OAJ15600.1 - 0.045 12.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DnaJ PF00226.31 OAJ15601.1 - 4.1e-23 81.3 0.2 6.8e-23 80.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 OAJ15601.1 - 1.7e-21 76.5 0.0 3.6e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) CCDC106 PF15794.5 OAJ15601.1 - 0.23 11.1 3.1 0.36 10.5 3.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PseudoU_synth_1 PF01416.20 OAJ15602.1 - 8e-24 84.2 0.1 5.5e-20 71.8 0.0 3.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase Caskin-Pro-rich PF16907.5 OAJ15602.1 - 0.085 13.4 2.6 0.43 11.1 2.6 2.2 1 0 0 1 1 1 0 Proline rich region of Caskin proteins CBF PF03914.17 OAJ15603.1 - 3.9e-22 79.1 0.7 3.9e-22 79.1 0.7 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DUF2052 PF09747.9 OAJ15603.1 - 2.9 8.0 9.3 0.42 10.7 3.5 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) adh_short PF00106.25 OAJ15604.1 - 7.7e-28 97.3 0.8 7.6e-26 90.8 0.8 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15604.1 - 3.3e-18 66.1 0.2 1.9e-16 60.4 0.2 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ15604.1 - 1.5e-07 31.1 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ15604.1 - 0.0011 18.9 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ15604.1 - 0.0075 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MBG PF17883.1 OAJ15604.1 - 0.035 14.7 0.0 0.08 13.5 0.0 1.6 1 0 0 1 1 1 0 MBG domain Mononeg_RNA_pol PF00946.19 OAJ15605.1 - 0.0074 14.0 1.1 0.0084 13.8 1.1 1.0 1 0 0 1 1 1 1 Mononegavirales RNA dependent RNA polymerase Cadherin_C_2 PF16492.5 OAJ15605.1 - 0.072 13.8 1.6 0.33 11.7 1.6 2.0 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal Alpha-amylase PF00128.24 OAJ15620.1 - 1.3e-96 324.1 0.0 1.8e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAJ15620.1 - 0.044 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF2838 PF10998.8 OAJ15621.1 - 3e-40 136.9 7.7 3e-40 136.9 7.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DUF454 PF04304.13 OAJ15621.1 - 0.17 11.9 4.0 1.3 9.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF454) DUF676 PF05057.14 OAJ15622.1 - 1e-31 110.2 0.0 1e-24 87.3 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) PAN_4 PF14295.6 OAJ15623.1 - 0.031 14.2 0.9 0.079 12.9 0.9 1.6 1 0 0 1 1 1 0 PAN domain Cellulase PF00150.18 OAJ15624.1 - 2.4e-11 43.6 7.1 3.8e-11 43.0 7.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L5e PF17144.4 OAJ15625.1 - 4.2e-76 254.5 0.0 5.6e-76 254.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAJ15625.1 - 1.7e-14 54.5 0.2 5e-14 53.0 0.2 1.8 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 OAJ15625.1 - 0.022 15.2 0.1 0.04 14.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L15e PF00827.17 OAJ15626.1 - 1e-86 289.6 6.1 1.2e-86 289.3 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF676 PF05057.14 OAJ15627.1 - 6.4e-30 104.3 0.0 1.6e-21 76.8 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAJ15627.1 - 0.00018 22.2 8.2 0.00023 21.9 0.5 2.8 1 1 2 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ15627.1 - 0.00094 19.0 0.1 0.0068 16.1 0.0 2.2 3 0 0 3 3 3 1 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ15627.1 - 0.074 12.3 0.3 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 F-box PF00646.33 OAJ15628.1 - 7e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain BCNT PF07572.12 OAJ15629.1 - 2.9e-15 56.1 2.8 1.2e-14 54.1 2.8 1.9 1 1 0 1 1 1 1 Bucentaur or craniofacial development Hamartin PF04388.12 OAJ15629.1 - 0.97 8.0 14.0 1.1 7.9 14.0 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 OAJ15629.1 - 4.5 6.0 8.5 6 5.6 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TANGO2 PF05742.12 OAJ15630.1 - 2.8e-49 168.5 0.0 3.5e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Alg6_Alg8 PF03155.15 OAJ15631.1 - 1.6e-152 508.9 10.8 6.5e-149 497.0 4.4 2.3 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family PGM_PMM_I PF02878.16 OAJ15632.1 - 1.6e-20 73.2 0.1 1.4e-10 41.0 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAJ15632.1 - 1.6e-09 37.8 0.1 4.2e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OAJ15632.1 - 1.7e-05 25.0 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ15632.1 - 0.15 12.7 0.2 2.4 8.8 0.2 3.0 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4210 PF13915.6 OAJ15633.1 - 7.9e-23 80.8 0.0 2e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAJ15633.1 - 6e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis adh_short PF00106.25 OAJ15633.1 - 8.1e-07 28.7 0.4 9.2e-05 22.0 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase TAF4 PF05236.14 OAJ15633.1 - 0.012 15.4 0.3 0.035 13.9 0.3 1.9 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family adh_short_C2 PF13561.6 OAJ15633.1 - 0.016 14.7 0.1 0.032 13.8 0.1 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase BHD_2 PF10404.9 OAJ15633.1 - 1.9 9.5 5.3 5.3 8.1 5.3 1.8 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Aldose_epim PF01263.20 OAJ15634.1 - 6.9e-30 104.4 0.1 8.6e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase SNF2_N PF00176.23 OAJ15635.1 - 4e-63 213.3 0.0 3.1e-61 207.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ15635.1 - 1.1e-20 74.0 0.4 8.8e-20 71.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAJ15635.1 - 7.3e-09 35.2 1.6 5.9e-07 28.9 0.0 3.0 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 OAJ15635.1 - 9.7e-09 35.4 0.0 7.7e-08 32.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RRN3 PF05327.11 OAJ15636.1 - 1.5 7.3 5.4 3 6.3 5.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 OAD_gamma PF04277.13 OAJ15649.1 - 0.083 13.5 0.1 0.62 10.7 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TFIIA PF03153.13 OAJ15649.1 - 4.8 7.1 28.2 0.99 9.3 7.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UbiA PF01040.18 OAJ15650.1 - 5.6e-51 173.3 26.4 1.1e-48 165.7 26.4 2.2 1 1 0 1 1 1 1 UbiA prenyltransferase family CRISPR_Cas6 PF10040.9 OAJ15650.1 - 0.057 14.1 0.0 0.18 12.4 0.0 2.0 1 1 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 Glucosamine_iso PF01182.20 OAJ15651.1 - 6.6e-75 251.8 0.0 8e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase tRNA-synt_2b PF00587.25 OAJ15652.1 - 5.2e-41 140.6 0.0 1e-40 139.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ15652.1 - 5.1e-14 52.2 2.5 7.9e-12 45.2 2.5 2.3 1 1 0 1 1 1 1 Anticodon binding domain RRM_1 PF00076.22 OAJ15653.1 - 8e-80 262.7 1.2 9.4e-19 67.0 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAJ15653.1 - 2.7e-26 91.5 0.2 6.6e-25 87.1 0.2 3.0 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAJ15653.1 - 2.5e-08 33.6 0.4 0.71 9.5 0.1 4.2 2 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ15653.1 - 0.00019 21.3 1.0 8.3 6.5 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ15653.1 - 0.00058 19.9 0.3 10 6.3 0.0 4.6 3 2 1 4 4 4 1 RNA recognition motif YflT PF11181.8 OAJ15653.1 - 0.021 15.3 0.5 2.7 8.6 0.2 2.7 2 0 0 2 2 2 0 Heat induced stress protein YflT Nefa_Nip30_N PF10187.9 OAJ15653.1 - 0.036 14.4 1.3 0.036 14.4 1.3 3.5 4 0 0 4 4 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 PGAP1 PF07819.13 OAJ15654.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Vps5 PF09325.10 OAJ15655.1 - 0.052 13.1 4.5 0.031 13.8 2.0 1.8 2 0 0 2 2 2 0 Vps5 C terminal like MFS_1 PF07690.16 OAJ15656.1 - 5.8e-09 35.3 13.8 0.00095 18.2 1.4 4.3 4 0 0 4 4 4 4 Major Facilitator Superfamily FAM176 PF14851.6 OAJ15656.1 - 3.1e-06 26.9 0.2 1.1 8.9 0.4 3.4 3 0 0 3 3 3 3 FAM176 family MFS_2 PF13347.6 OAJ15656.1 - 0.087 11.4 11.6 0.44 9.0 1.2 4.5 5 0 0 5 5 5 0 MFS/sugar transport protein Myc_N PF01056.18 OAJ15656.1 - 0.096 12.6 6.2 0.2 11.5 0.2 2.9 3 0 0 3 3 3 0 Myc amino-terminal region PBP1_TM PF14812.6 OAJ15656.1 - 0.12 12.7 3.5 3.8 7.9 0.1 3.9 4 0 0 4 4 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MscS_TM PF12794.7 OAJ15656.1 - 0.27 10.1 11.6 2.6 6.8 0.1 4.3 4 1 1 5 5 5 0 Mechanosensitive ion channel inner membrane domain 1 DUF4366 PF14283.6 OAJ15656.1 - 0.35 10.9 2.2 0.7 9.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2749 PF10907.8 OAJ15656.1 - 0.64 10.2 2.9 2 8.6 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF3169 PF11368.8 OAJ15656.1 - 1.7 8.1 4.9 3.7 7.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3169) Sugar_tr PF00083.24 OAJ15656.1 - 4 6.2 7.0 3 6.6 0.2 3.4 3 1 1 4 4 4 0 Sugar (and other) transporter PNISR PF15996.5 OAJ15656.1 - 7.6 6.8 10.7 0.93 9.7 0.1 3.0 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR GrpE PF01025.19 OAJ15657.1 - 7.3e-44 149.4 0.0 1e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 GrpE MukF_M PF17192.4 OAJ15657.1 - 0.1 12.4 1.1 1.6 8.5 0.5 2.2 1 1 1 2 2 2 0 MukF middle domain TB2_DP1_HVA22 PF03134.19 OAJ15658.1 - 3.9e-25 87.6 6.6 3.9e-25 87.6 6.6 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DNA_topoisoIV PF00521.20 OAJ15659.1 - 1.7e-130 435.8 0.4 5.7e-130 434.0 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAJ15659.1 - 1.1e-47 161.6 0.4 1.1e-47 161.6 0.4 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAJ15659.1 - 9.4e-29 100.1 1.0 2e-28 99.1 1.0 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAJ15659.1 - 5.3e-13 49.5 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAJ15659.1 - 4.7e-08 33.2 0.1 3e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 Toprim domain APH PF01636.23 OAJ15660.1 - 5.6e-05 23.2 0.0 2.1 8.2 0.0 3.0 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ15660.1 - 8.7e-05 22.0 0.0 0.032 13.6 0.0 3.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAJ15660.1 - 0.0045 16.4 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 OAJ15660.1 - 0.04 13.2 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 OAJ15660.1 - 0.046 13.3 0.0 9.6 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Sel1 PF08238.12 OAJ15661.1 - 1.2e-13 51.3 21.4 6.7e-06 26.6 0.9 4.5 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 OAJ15661.1 - 3.7 7.9 5.8 8.9 6.7 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ15661.1 - 5 7.1 5.3 10 6.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Rot1 PF10681.9 OAJ15675.1 - 1.8e-47 161.6 1.6 2.2e-47 161.3 1.6 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal ODV-E18 PF10717.9 OAJ15675.1 - 8.4 6.3 7.4 27 4.7 6.3 2.4 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 VMA21 PF09446.10 OAJ15676.1 - 3.7e-13 49.4 9.3 5.4e-13 48.8 9.3 1.3 1 0 0 1 1 1 1 VMA21-like domain Methyltransf_8 PF05148.15 OAJ15677.1 - 5e-53 180.2 0.0 3.4e-27 95.7 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_31 PF13847.6 OAJ15677.1 - 0.013 15.3 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ15677.1 - 0.028 15.1 0.0 5.6 7.8 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 OAJ15677.1 - 0.058 12.9 0.1 7.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Methyltransferase small domain DUF3140 PF11338.8 OAJ15678.1 - 2.7e-33 114.2 1.6 3.3e-33 114.0 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 OAJ15678.1 - 0.022 15.2 0.1 0.035 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) GCIP PF13324.6 OAJ15678.1 - 0.053 13.1 0.9 0.062 12.9 0.9 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Lipoprotein_Ltp PF07553.11 OAJ15678.1 - 0.062 13.6 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein DUF3673 PF12425.8 OAJ15678.1 - 0.15 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) NOA36 PF06524.12 OAJ15679.1 - 9 5.5 6.6 8.4 5.6 5.4 1.5 2 0 0 2 2 2 0 NOA36 protein GDI PF00996.18 OAJ15680.1 - 1.1e-31 109.9 0.0 2.8e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor GMC_oxred_N PF00732.19 OAJ15680.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Herpes_gE PF02480.16 OAJ15680.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E KH_6 PF15985.5 OAJ15681.1 - 1.8e-08 34.6 0.0 4.1e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 OAJ15681.1 - 2.6e-07 30.3 0.1 5.3e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Sec7 PF01369.20 OAJ15682.1 - 2.2e-71 239.3 0.1 5e-71 238.2 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ15682.1 - 1.9e-44 151.3 4.8 1.9e-44 151.3 4.8 3.2 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAJ15682.1 - 1.2e-26 92.3 0.9 2.4e-25 88.2 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAJ15682.1 - 9.2e-20 71.0 2.8 1.5e-18 67.1 0.0 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 RNA_pol_Rpc34 PF05158.12 OAJ15684.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit GIY-YIG PF01541.24 OAJ15684.1 - 0.042 14.1 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 GIY-YIG catalytic domain DUF2525 PF10733.9 OAJ15684.1 - 0.11 12.7 0.2 0.42 10.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) RFC1 PF08519.12 OAJ15686.1 - 8.3e-51 172.3 0.0 2e-50 171.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAJ15686.1 - 9.9e-11 41.9 0.0 3e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAJ15686.1 - 3.9e-10 40.3 0.1 3.2e-09 37.3 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ15686.1 - 1.3e-07 31.8 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAJ15686.1 - 0.0017 18.7 0.0 0.0072 16.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 OAJ15686.1 - 0.0035 17.1 0.1 0.052 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ15686.1 - 0.0045 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ15686.1 - 0.005 17.1 0.0 0.047 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ15686.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ15686.1 - 0.0067 17.0 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OAJ15686.1 - 0.013 15.3 0.2 0.056 13.2 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 OAJ15686.1 - 0.025 14.5 0.1 0.32 10.9 0.2 2.5 2 0 0 2 2 2 0 NTPase AAA_assoc_2 PF16193.5 OAJ15686.1 - 0.026 14.8 0.0 0.14 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 OAJ15686.1 - 0.059 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IPP-2 PF04979.14 OAJ15687.1 - 1.7e-18 67.7 3.9 1.8e-08 35.2 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) WW PF00397.26 OAJ15688.1 - 3.8e-09 36.5 2.0 6.5e-09 35.7 2.0 1.4 1 0 0 1 1 1 1 WW domain Rgp1 PF08737.10 OAJ15689.1 - 2.7e-82 277.2 0.0 6e-82 276.0 0.0 1.6 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 OAJ15689.1 - 1.1e-07 32.0 1.1 0.031 14.3 0.0 3.4 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 OAJ15689.1 - 0.032 13.8 0.1 5.8 6.4 0.1 2.3 2 0 0 2 2 2 0 SpoOM protein DPBB_1 PF03330.18 OAJ15690.1 - 0.001 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase LSM PF01423.22 OAJ15691.1 - 1.7e-16 59.6 0.2 2.4e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Abhydrolase_3 PF07859.13 OAJ15692.1 - 4.8e-18 65.8 0.1 1.8e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ15692.1 - 9.1e-10 37.9 0.0 5.9e-07 28.7 0.0 2.8 2 1 0 2 2 2 2 Steryl acetyl hydrolase Nucleo_P87 PF07267.11 OAJ15692.1 - 0.041 12.8 2.0 0.14 10.9 2.0 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spem1 PF15670.5 OAJ15692.1 - 9.5 5.7 7.6 4.1 6.9 3.3 2.5 3 0 0 3 3 3 0 Spermatid maturation protein 1 PCI PF01399.27 OAJ15693.1 - 2.2e-05 24.9 0.0 4.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain polyprenyl_synt PF00348.17 OAJ15694.1 - 1.3e-90 302.9 0.0 1.7e-90 302.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1279 PF06916.13 OAJ15706.1 - 0.16 12.6 0.0 0.43 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) EF1_GNE PF00736.19 OAJ15709.1 - 1.6e-33 114.7 1.2 2.8e-33 114.0 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAJ15709.1 - 4.4e-13 49.4 6.4 4.4e-13 49.4 6.4 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 OAJ15709.1 - 0.00023 21.3 0.1 0.00069 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ15709.1 - 0.00039 20.4 0.4 0.0056 16.7 0.4 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ15709.1 - 0.028 14.6 0.6 0.15 12.3 0.0 2.5 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF211 PF02680.14 OAJ15709.1 - 0.16 12.1 0.8 0.55 10.4 0.4 1.9 1 1 1 2 2 2 0 Uncharacterized ArCR, COG1888 DUF3246 PF11596.8 OAJ15709.1 - 0.18 11.2 0.8 0.26 10.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CLTH PF10607.9 OAJ15710.1 - 5.8e-17 61.9 0.0 1.5e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4248 PF14053.6 OAJ15710.1 - 0.12 12.4 0.5 0.32 11.0 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) LON_substr_bdg PF02190.16 OAJ15711.1 - 5.4e-18 65.6 0.0 9.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAJ15711.1 - 2.6e-17 62.3 21.1 1.6e-12 47.0 9.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ15711.1 - 1.4e-12 47.4 18.1 1e-06 28.7 2.2 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAJ15711.1 - 8.2e-12 45.1 21.0 7e-07 29.3 3.3 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAJ15711.1 - 9.4e-12 44.6 17.9 9.1e-08 31.8 5.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ15711.1 - 1.2e-10 41.5 20.3 1.6e-07 31.5 9.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 OAJ15711.1 - 3.8e-10 39.5 19.7 1.9e-05 24.5 8.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ15711.1 - 2.3e-09 37.0 19.4 1.7e-05 24.7 8.3 2.4 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ15711.1 - 2.9e-08 33.4 20.0 8.8e-07 28.7 6.8 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 OAJ15711.1 - 0.00043 20.1 11.5 0.028 14.3 2.3 2.5 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OAJ15711.1 - 0.0027 17.4 3.0 0.0027 17.4 3.0 3.0 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 OAJ15711.1 - 0.003 17.7 16.2 0.0047 17.0 4.2 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 OAJ15711.1 - 0.038 14.3 12.8 0.02 15.1 5.8 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain U-box PF04564.15 OAJ15711.1 - 0.12 12.6 0.0 0.41 10.8 0.0 1.9 2 0 0 2 2 2 0 U-box domain Kelch_6 PF13964.6 OAJ15712.1 - 3.7e-10 39.7 1.2 0.14 12.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 OAJ15712.1 - 5.9e-09 35.8 0.2 0.0088 16.0 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ15712.1 - 2.2e-07 30.7 0.0 0.0013 18.7 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 OAJ15712.1 - 2e-05 24.4 0.3 0.014 15.3 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 OAJ15712.1 - 2.4e-05 24.5 0.1 2.4e-05 24.5 0.1 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ15712.1 - 0.00033 20.2 0.0 3.6 7.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif DUF3712 PF12505.8 OAJ15713.1 - 3.1e-106 350.5 38.3 6.4e-24 84.6 1.6 7.6 7 0 0 7 7 7 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ15713.1 - 4.4e-07 30.4 17.2 0.0011 19.5 0.1 7.1 8 0 0 8 8 8 2 Late embryogenesis abundant protein Bactofilin PF04519.13 OAJ15713.1 - 0.23 11.8 1.2 23 5.4 0.5 3.5 3 0 0 3 3 3 0 Polymer-forming cytoskeletal Gpi1 PF05024.15 OAJ15714.1 - 2.3e-56 190.8 1.4 3.8e-56 190.2 1.4 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Aldo_ket_red PF00248.21 OAJ15715.1 - 3e-11 43.1 0.0 2.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family ELFV_dehydrog PF00208.21 OAJ15716.1 - 2.2e-51 174.9 0.0 3.4e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAJ15716.1 - 7.5e-19 66.9 0.0 2.8e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase adh_short PF00106.25 OAJ15718.1 - 3.6e-22 78.8 0.0 4.6e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ15718.1 - 3.2e-17 62.9 0.0 3.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ15718.1 - 1.4e-10 41.4 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ15718.1 - 7.8e-07 28.8 0.1 4.7e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAJ15718.1 - 9.2e-06 25.0 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 OAJ15718.1 - 0.00057 19.4 0.0 0.089 12.2 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 OAJ15718.1 - 0.006 16.7 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ15718.1 - 0.015 15.8 0.2 0.049 14.2 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAJ15718.1 - 0.022 14.7 0.4 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhzC-PhzF PF02567.16 OAJ15718.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DUF1776 PF08643.10 OAJ15718.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 OAJ15718.1 - 0.073 12.1 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPPC10 PF12584.8 OAJ15719.1 - 1.1e-19 70.7 0.0 2.4e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 WTF PF03303.13 OAJ15720.1 - 0.021 14.5 0.3 0.035 13.9 0.3 1.3 1 0 0 1 1 1 0 WTF protein NAC PF01849.18 OAJ15736.1 - 3.2e-21 75.1 0.2 5.2e-21 74.4 0.2 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_G PF04718.15 OAJ15737.1 - 1.7e-16 60.8 1.2 5.1e-16 59.3 0.0 2.1 1 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF1178 PF06676.11 OAJ15737.1 - 0.71 10.2 4.4 0.99 9.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Uso1_p115_C PF04871.13 OAJ15737.1 - 0.79 10.1 8.4 1.1 9.6 8.4 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Dsh_C PF12316.8 OAJ15737.1 - 2.3 8.6 15.4 3.1 8.2 15.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF5427 PF10310.9 OAJ15737.1 - 3 6.7 8.7 3.8 6.4 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Pkinase PF00069.25 OAJ15738.1 - 2.4e-64 217.3 0.0 2.9e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15738.1 - 1.7e-31 109.4 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ15738.1 - 8.5e-06 24.9 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ15738.1 - 0.00054 20.0 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ15738.1 - 0.0014 18.1 0.0 0.0035 16.7 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ15738.1 - 0.0065 15.8 0.0 0.095 12.0 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ15738.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAJ15738.1 - 0.028 14.0 0.1 0.063 12.9 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_15 PF00723.21 OAJ15739.1 - 5.7e-82 275.9 0.3 7.8e-82 275.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Col_cuticle_N PF01484.17 OAJ15739.1 - 0.42 10.7 2.4 10 6.3 2.2 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain WD40 PF00400.32 OAJ15740.1 - 1.2e-42 143.0 24.3 5.7e-05 23.8 0.1 12.1 12 1 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15740.1 - 2.1e-21 76.0 0.2 0.0013 19.0 0.0 8.3 5 3 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 OAJ15740.1 - 5.6e-18 65.2 0.8 1.3e-17 64.0 0.8 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 OAJ15740.1 - 2.9e-06 26.3 0.3 1.6 7.3 0.0 4.2 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAJ15740.1 - 0.00027 20.0 0.0 2.6 6.9 0.0 4.7 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 OAJ15740.1 - 0.00095 18.5 0.0 0.022 14.0 0.0 2.9 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 OAJ15740.1 - 0.022 14.1 0.2 0.29 10.4 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal ELYS-bb PF16687.5 OAJ15740.1 - 0.095 11.3 0.0 0.31 9.6 0.0 1.9 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin CS PF04969.16 OAJ15741.1 - 4.1e-07 30.9 0.0 8.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 CS domain Pkinase PF00069.25 OAJ15742.1 - 2.6e-62 210.6 0.0 2.5e-61 207.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15742.1 - 2.4e-34 118.8 0.0 6.1e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAJ15742.1 - 4.7e-24 84.3 18.3 4.2e-15 55.6 7.1 3.9 5 0 0 5 5 5 2 Hr1 repeat C1_1 PF00130.22 OAJ15742.1 - 8.9e-20 70.3 24.4 8.7e-11 41.5 10.8 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAJ15742.1 - 6.7e-08 33.1 2.1 2.1e-07 31.6 2.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 OAJ15742.1 - 0.00042 20.6 0.1 0.00088 19.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 OAJ15742.1 - 0.00075 18.9 0.0 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ15742.1 - 0.019 14.6 0.2 1.5 8.4 0.1 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 OAJ15742.1 - 0.33 11.3 17.8 0.51 10.7 3.7 2.4 2 0 0 2 2 2 0 C1 domain FYVE_2 PF02318.16 OAJ15742.1 - 3.8 7.8 15.5 17 5.6 6.3 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger IKI3 PF04762.12 OAJ15743.1 - 0.3 9.0 0.7 0.3 9.0 0.7 1.0 1 0 0 1 1 1 0 IKI3 family Pox_polyA_pol PF03296.13 OAJ15744.1 - 0.087 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain TMEM237 PF15383.6 OAJ15745.1 - 0.00015 21.0 0.0 0.0004 19.6 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 237 Sugarporin_N PF11471.8 OAJ15745.1 - 0.088 12.8 1.7 0.25 11.3 1.7 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SRP-alpha_N PF04086.13 OAJ15745.1 - 7.4 6.4 11.4 16 5.3 11.4 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal WD40 PF00400.32 OAJ15746.1 - 6.3e-52 172.4 22.2 2.1e-09 37.8 0.5 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15746.1 - 3.3e-18 65.8 0.4 4.9e-05 23.6 0.0 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ15746.1 - 5.7e-09 35.2 5.1 0.75 8.4 0.0 5.9 3 1 3 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 OAJ15746.1 - 2.1e-08 34.3 0.0 0.001 19.0 0.0 3.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 OAJ15746.1 - 1.4e-07 30.8 3.1 0.0048 15.9 0.0 4.7 2 1 3 5 5 5 3 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAJ15746.1 - 6.3e-06 25.4 0.4 0.47 9.4 0.0 4.8 2 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ15746.1 - 4.9e-05 22.8 0.1 0.00079 18.8 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Frtz PF11768.8 OAJ15746.1 - 0.0038 15.6 0.1 0.018 13.4 0.0 2.1 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Motile_Sperm PF00635.26 OAJ15747.1 - 9.6e-26 89.8 0.1 2e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 OAJ15747.1 - 0.00078 19.6 0.2 0.0032 17.6 0.2 2.1 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 OAJ15747.1 - 0.0026 18.0 0.2 0.0054 17.0 0.2 1.4 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase fn3_6 PF17766.1 OAJ15747.1 - 0.029 14.5 0.1 0.067 13.4 0.1 1.6 1 0 0 1 1 1 0 Fibronectin type-III domain DUF5001 PF16392.5 OAJ15747.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Ig-like domain Tcp11 PF05794.13 OAJ15748.1 - 4.4e-93 312.8 0.0 1.2e-91 308.1 0.0 2.6 1 1 0 1 1 1 1 T-complex protein 11 Acatn PF13000.7 OAJ15749.1 - 1.6e-158 528.7 18.4 3e-79 267.0 12.7 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 TPR_2 PF07719.17 OAJ15765.1 - 0.00012 21.9 1.3 1.1 9.5 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15765.1 - 0.0081 16.4 3.0 1.5 9.1 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TIP49 PF06068.13 OAJ15766.1 - 1.3e-58 199.0 0.0 1.5e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain MFS_1 PF07690.16 OAJ15767.1 - 4.4e-36 124.5 74.9 1.4e-31 109.7 44.2 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 OAJ15767.1 - 0.085 12.6 0.0 0.085 12.6 0.0 2.4 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term zf-CCCH_3 PF15663.5 OAJ15768.1 - 0.36 11.1 4.8 6.5 7.0 4.7 2.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAJ15768.1 - 0.38 10.6 16.0 0.43 10.4 5.9 3.0 2 2 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ15768.1 - 0.62 10.2 11.2 1.2 9.3 0.3 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-C3H1 PF10650.9 OAJ15768.1 - 0.94 9.3 6.6 1.1 9.0 1.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH PF00642.24 OAJ15768.1 - 1.2 9.1 13.0 4.6 7.3 1.0 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAJ15768.1 - 1.9 9.1 11.0 1.6 9.3 3.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_L31e PF01198.19 OAJ15769.1 - 1.1e-36 124.9 1.6 1.8e-36 124.2 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e DUF3535 PF12054.8 OAJ15770.1 - 9.3e-103 344.8 0.0 3.4e-101 339.6 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAJ15770.1 - 3.4e-60 203.6 0.0 5.7e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ15770.1 - 2.4e-16 60.0 0.0 5.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAJ15770.1 - 2.6e-11 42.8 29.4 0.12 12.7 0.2 11.1 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ15770.1 - 0.043 14.4 0.0 0.64 10.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 OAJ15770.1 - 0.37 11.3 27.4 3.2 8.3 0.0 11.0 12 1 1 13 13 13 0 HEAT-like repeat HEAT_2 PF13646.6 OAJ15770.1 - 0.5 10.8 25.4 3.7 8.0 0.2 9.2 9 2 0 9 9 9 0 HEAT repeats CDP-OH_P_transf PF01066.21 OAJ15771.1 - 1.4e-12 48.2 0.2 3.4e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase RNA_POL_M_15KD PF02150.16 OAJ15772.1 - 1.1e-13 50.8 3.7 1.1e-13 50.8 3.7 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 OAJ15772.1 - 4e-10 39.4 13.8 7.5e-10 38.5 4.1 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 OAJ15772.1 - 0.0029 17.7 8.0 1.2 9.3 0.1 3.9 4 0 0 4 4 4 2 Zinc ribbon domain GFA PF04828.14 OAJ15772.1 - 0.0046 17.3 7.7 0.011 16.0 0.1 2.7 1 1 2 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.6 OAJ15772.1 - 0.17 12.6 3.3 1.6 9.4 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 CpXC PF14353.6 OAJ15772.1 - 0.8 9.8 7.2 21 5.2 0.2 2.7 1 1 1 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 OAJ15772.1 - 0.83 9.7 11.6 6.8 6.8 4.3 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF3268 PF11672.8 OAJ15772.1 - 0.84 10.0 6.7 4 7.8 1.7 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain TF_Zn_Ribbon PF08271.12 OAJ15772.1 - 0.91 9.1 12.0 0.31 10.6 3.3 3.4 3 1 1 4 4 4 0 TFIIB zinc-binding Rpr2 PF04032.16 OAJ15772.1 - 8.4 6.8 11.1 1.6e+02 2.7 11.2 2.9 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-HIT PF04438.16 OAJ15773.1 - 1.6e-09 37.5 10.0 2.3e-09 36.9 10.0 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 OAJ15773.1 - 0.28 11.4 8.1 0.26 11.5 6.8 1.5 2 0 0 2 2 2 0 B-box zinc finger zf-MYND PF01753.18 OAJ15773.1 - 4.6 7.4 10.7 8.1 6.6 10.7 1.4 1 0 0 1 1 1 0 MYND finger CM_2 PF01817.21 OAJ15774.1 - 0.0044 17.3 0.0 0.2 12.1 0.0 2.4 2 1 0 2 2 2 2 Chorismate mutase type II Tetraspanin PF00335.20 OAJ15775.1 - 6.4e-05 22.8 3.6 6.4e-05 22.8 3.6 1.6 1 1 1 2 2 2 1 Tetraspanin family Wzy_C PF04932.15 OAJ15775.1 - 0.0087 15.7 0.0 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 O-Antigen ligase Tetraspanin PF00335.20 OAJ15776.1 - 1e-05 25.4 2.2 1e-05 25.4 2.2 2.0 1 1 1 2 2 2 1 Tetraspanin family DUF2569 PF10754.9 OAJ15776.1 - 0.16 12.4 5.6 0.26 11.7 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) COX14 PF14880.6 OAJ15776.1 - 0.61 10.0 3.0 9.8 6.1 0.0 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly SLATT_1 PF18181.1 OAJ15776.1 - 4.2 7.3 5.6 3.2 7.7 1.9 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 TIP49 PF06068.13 OAJ15777.1 - 3.5e-150 500.1 0.0 4.7e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ15777.1 - 7.4e-24 83.7 1.2 4e-23 81.3 1.5 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ15777.1 - 5.1e-12 46.4 0.1 4.8e-09 36.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ15777.1 - 1.1e-11 44.7 1.5 1.7e-08 34.3 0.1 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ15777.1 - 7.4e-07 29.7 0.1 2.3e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OAJ15777.1 - 1.9e-06 27.4 0.3 3.8e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OAJ15777.1 - 2.5e-06 27.8 0.1 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ15777.1 - 1.3e-05 25.3 0.2 0.0046 17.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ15777.1 - 2.5e-05 23.8 0.6 0.0009 18.7 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ15777.1 - 2.7e-05 24.5 0.3 0.00022 21.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAJ15777.1 - 7.7e-05 22.5 0.0 0.094 12.4 0.1 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 OAJ15777.1 - 0.00078 19.1 0.2 0.0032 17.1 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 OAJ15777.1 - 0.00097 19.6 0.1 0.0023 18.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 OAJ15777.1 - 0.0013 17.9 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 OAJ15777.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 OAJ15777.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OAJ15777.1 - 0.0052 17.3 0.0 0.0052 17.3 0.0 2.3 3 0 0 3 3 1 1 AAA domain AAA_7 PF12775.7 OAJ15777.1 - 0.0065 16.0 0.1 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 OAJ15777.1 - 0.01 15.6 0.3 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAJ15777.1 - 0.011 15.8 0.3 0.027 14.5 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ15777.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAJ15777.1 - 0.013 14.7 0.2 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OAJ15777.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAJ15777.1 - 0.021 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 OAJ15777.1 - 0.023 14.7 0.1 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 OAJ15777.1 - 0.026 15.0 0.1 0.039 14.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAJ15777.1 - 0.028 14.5 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 OAJ15777.1 - 0.034 13.6 0.1 0.084 12.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAJ15777.1 - 0.038 14.2 0.1 0.095 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAJ15777.1 - 0.048 13.8 0.1 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_32 PF13654.6 OAJ15777.1 - 0.062 12.1 0.3 0.13 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 OAJ15777.1 - 0.065 13.1 0.4 0.23 11.4 0.1 2.2 2 1 0 2 2 1 0 NTPase RNA_helicase PF00910.22 OAJ15777.1 - 0.074 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAJ15777.1 - 0.14 11.9 0.2 3.3 7.5 0.0 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain Tetraspanin PF00335.20 OAJ15778.1 - 0.00031 20.5 5.6 0.01 15.6 6.9 2.1 1 1 1 2 2 2 1 Tetraspanin family DUF2569 PF10754.9 OAJ15778.1 - 0.0044 17.5 2.9 0.055 13.9 1.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) Wzy_C_2 PF11846.8 OAJ15778.1 - 0.027 14.4 1.4 0.053 13.4 0.0 2.1 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Wzy_C PF04932.15 OAJ15778.1 - 0.17 11.5 0.1 0.17 11.5 0.1 1.9 3 0 0 3 3 3 0 O-Antigen ligase PalH PF08733.10 OAJ15778.1 - 0.43 9.5 3.5 0.49 9.3 1.1 1.8 1 1 1 2 2 2 0 PalH/RIM21 Tetraspanin PF00335.20 OAJ15779.1 - 0.04 13.6 1.4 0.13 11.9 1.4 1.9 1 1 0 1 1 1 0 Tetraspanin family Pkinase PF00069.25 OAJ15780.1 - 8e-48 163.1 0.0 1.5e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15780.1 - 2.5e-18 66.3 0.0 5.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-C_C PF11699.8 OAJ15792.1 - 8e-28 96.5 0.5 1.3e-27 95.8 0.5 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OAJ15792.1 - 0.00023 20.8 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 OAJ15792.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain 60KD_IMP PF02096.20 OAJ15793.1 - 8.9e-09 35.5 0.6 1.6e-07 31.4 0.6 2.5 1 1 0 1 1 1 1 60Kd inner membrane protein Polysacc_deac_1 PF01522.21 OAJ15794.1 - 1.2e-28 99.5 0.0 2.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 2OG-FeII_Oxy_2 PF13532.6 OAJ15795.1 - 1.9e-24 87.0 0.2 3.5e-24 86.1 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 OAJ15796.1 - 1.4e-63 215.2 0.0 2.2e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 OAJ15798.1 - 6e-42 144.2 22.1 3.5e-25 89.2 8.7 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ15798.1 - 1.6e-22 80.5 0.1 5.7e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.6 OAJ15798.1 - 2.9e-06 27.9 0.8 0.0045 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OAJ15798.1 - 0.00046 19.7 0.6 4.3 6.7 0.1 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ15798.1 - 0.00048 19.8 0.7 0.98 9.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ15798.1 - 0.00098 19.4 0.8 0.92 9.8 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAJ15798.1 - 0.006 16.2 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 OAJ15798.1 - 0.01 15.9 0.5 0.76 9.9 0.5 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ15798.1 - 0.017 15.0 0.2 4.7 7.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 OAJ15798.1 - 0.092 11.7 0.4 0.17 10.8 0.4 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 OAJ15798.1 - 0.099 12.8 0.2 7.1 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAJ15798.1 - 0.11 12.6 0.9 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 OAJ15798.1 - 0.11 11.8 1.0 28 3.9 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.6 OAJ15798.1 - 0.24 11.8 9.3 0.43 11.0 0.2 3.8 3 1 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.15 OAJ15798.1 - 0.53 10.2 1.7 0.68 9.8 0.3 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_7 PF12775.7 OAJ15798.1 - 0.87 9.1 4.1 0.76 9.3 0.3 2.4 3 0 0 3 3 3 0 P-loop containing dynein motor region TAF8_C PF10406.9 OAJ15800.1 - 0.52 10.9 11.6 1.2 9.7 11.6 1.7 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term HEAT_2 PF13646.6 OAJ15801.1 - 1.6e-20 73.2 16.1 3e-12 46.8 0.3 5.0 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 OAJ15801.1 - 1.5e-12 46.6 2.5 0.17 12.2 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 OAJ15801.1 - 3.8e-10 39.5 8.1 0.0028 18.2 0.0 7.3 8 0 0 8 8 8 2 PBS lyase HEAT-like repeat Arm PF00514.23 OAJ15801.1 - 0.0071 16.3 0.0 3.6 7.8 0.0 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat CDC45 PF02724.14 OAJ15802.1 - 0.64 8.2 3.0 0.66 8.2 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ15802.1 - 3.1 5.8 7.0 3.9 5.4 7.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi HEXIM PF15313.6 OAJ15802.1 - 3.3 7.9 7.0 1 9.5 3.4 2.0 1 1 1 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Glyco_transf_28 PF03033.20 OAJ15803.1 - 6.7e-25 87.8 0.0 1.2e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ15803.1 - 7.7e-05 22.6 0.0 0.26 11.2 0.0 2.8 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 OAJ15803.1 - 0.00065 20.2 0.0 0.0019 18.7 0.0 1.8 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 OAJ15803.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PHD PF00628.29 OAJ15804.1 - 1.7e-13 50.2 20.4 1e-08 34.9 8.8 2.8 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 OAJ15804.1 - 2.7 7.6 5.3 0.73 9.4 2.1 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 OAJ15804.1 - 4.3 7.0 9.3 16 5.2 0.5 2.8 2 0 0 2 2 2 0 PHD-finger XRCC4 PF06632.12 OAJ15804.1 - 8.3 5.2 5.9 3.2 6.5 0.1 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Peptidase_M41 PF01434.18 OAJ15805.1 - 3.9e-62 209.5 0.9 4.9e-62 209.2 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 OAJ15805.1 - 8.7e-42 142.7 0.0 2.2e-41 141.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ15805.1 - 1.2e-12 47.4 0.2 2.9e-12 46.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAJ15805.1 - 2.2e-11 44.0 1.6 2.4e-11 44.0 0.0 1.9 2 0 0 2 2 1 1 FtsH Extracellular AAA_22 PF13401.6 OAJ15805.1 - 0.0023 18.2 0.1 0.5 10.6 0.1 2.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAJ15805.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAJ15805.1 - 0.011 16.1 0.2 0.22 11.9 0.2 2.6 1 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 OAJ15805.1 - 0.017 15.2 0.1 0.1 12.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ15805.1 - 0.024 14.4 0.0 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 OAJ15805.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 OAJ15805.1 - 0.093 12.8 0.0 0.44 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rgp1 PF08737.10 OAJ15805.1 - 0.35 10.0 5.2 0.65 9.1 5.2 1.3 1 0 0 1 1 1 0 Rgp1 Macoilin PF09726.9 OAJ15805.1 - 9.5 4.6 10.2 16 3.9 10.2 1.2 1 0 0 1 1 1 0 Macoilin family PI3_PI4_kinase PF00454.27 OAJ15819.1 - 1.5e-32 113.4 0.0 2.9e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OAJ15819.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Spt20 PF12090.8 OAJ15819.1 - 5.4 6.6 12.0 11 5.6 0.6 2.4 2 0 0 2 2 2 0 Spt20 family DUF3712 PF12505.8 OAJ15820.1 - 3.8e-112 369.6 35.2 1.8e-24 86.4 0.2 9.5 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ15820.1 - 0.00011 22.7 21.0 0.13 12.8 0.1 8.7 10 0 0 10 10 10 3 Late embryogenesis abundant protein LON_substr_bdg PF02190.16 OAJ15821.1 - 4.5e-06 26.7 0.0 4.8e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain CAP PF00188.26 OAJ15822.1 - 1.1e-19 71.5 0.6 2.5e-19 70.3 0.6 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Tyrosinase PF00264.20 OAJ15822.1 - 0.035 14.4 3.8 0.051 13.9 3.8 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF908 PF06012.12 OAJ15822.1 - 0.92 8.9 9.0 1.2 8.5 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TFIIA PF03153.13 OAJ15822.1 - 8.6 6.2 6.0 11 5.9 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAS20 PF02064.15 OAJ15824.1 - 9.9e-27 93.6 0.2 3.5e-26 91.8 0.2 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor Formyl_trans_N PF00551.19 OAJ15825.1 - 9.7e-35 119.9 0.0 1.5e-33 116.1 0.0 2.3 1 1 0 1 1 1 1 Formyl transferase Thioredoxin PF00085.20 OAJ15826.1 - 8.3e-29 99.6 0.0 1.2e-21 76.6 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 OAJ15826.1 - 6e-07 29.1 0.0 2.4e-05 23.9 0.1 2.6 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 OAJ15826.1 - 2.5e-05 24.3 0.0 0.0073 16.5 0.1 3.1 2 2 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ15826.1 - 5.7e-05 23.5 0.5 0.00031 21.2 0.2 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ15826.1 - 0.00049 20.0 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ15826.1 - 0.016 15.5 0.0 0.064 13.6 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like Cupin_8 PF13621.6 OAJ15827.1 - 3.1e-54 184.4 0.0 4e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 OAJ15827.1 - 0.00038 20.1 0.0 0.62 9.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain JmjC PF02373.22 OAJ15827.1 - 0.0011 19.4 0.0 0.037 14.4 0.0 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase Proteasome PF00227.26 OAJ15828.1 - 7.7e-55 185.3 0.1 9.5e-55 185.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ15828.1 - 9.9e-14 50.7 0.1 1.9e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DS PF01916.17 OAJ15829.1 - 5.1e-132 439.5 0.0 5.9e-132 439.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RNase_H2_suC PF08615.11 OAJ15830.1 - 4.7e-08 33.3 0.3 4.7e-08 33.3 0.3 4.8 2 2 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) ETC_C1_NDUFA4 PF04800.12 OAJ15831.1 - 1.9e-34 117.8 0.2 2.8e-34 117.2 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region AAA_lid_2 PF17863.1 OAJ15831.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA lid domain TRIC PF05197.13 OAJ15832.1 - 9.6e-06 25.3 1.5 6.3e-05 22.6 0.1 2.7 1 1 1 2 2 2 1 TRIC channel UPF0126 PF03458.13 OAJ15832.1 - 0.00076 19.3 4.2 0.36 10.8 0.7 2.8 2 0 0 2 2 2 2 UPF0126 domain COPIIcoated_ERV PF07970.12 OAJ15833.1 - 5.4e-78 261.8 0.0 7.7e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ15833.1 - 1.2e-26 92.8 0.1 4.4e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RWD PF05773.22 OAJ15834.1 - 4.3e-19 68.9 0.2 8e-19 68.0 0.2 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 OAJ15834.1 - 1.3e-05 25.6 12.1 6e-05 23.5 11.9 2.4 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 AAR2 PF05282.11 OAJ15834.1 - 0.73 9.2 3.7 0.69 9.3 2.6 1.4 1 1 1 2 2 2 0 AAR2 protein PNP_phzG_C PF10590.9 OAJ15835.1 - 3e-20 72.0 3.2 5.6e-20 71.1 3.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAJ15835.1 - 1.7e-17 63.3 0.0 1.4e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Alpha-amylase PF00128.24 OAJ15835.1 - 0.058 12.9 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, catalytic domain FAD-oxidase_C PF02913.19 OAJ15852.1 - 9e-62 208.9 0.0 1.3e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ15852.1 - 4.5e-35 120.4 0.7 8.1e-35 119.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.14 OAJ15852.1 - 0.073 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Ilar_coat PF01787.16 OAJ15852.1 - 0.084 12.7 0.9 1 9.1 0.0 2.7 2 1 1 3 3 3 0 Ilarvirus coat protein CHCH PF06747.13 OAJ15853.1 - 0.00012 22.1 5.1 0.00012 22.1 5.1 2.4 2 1 0 2 2 2 2 CHCH domain CX9C PF16860.5 OAJ15853.1 - 0.00018 21.5 10.5 0.0036 17.3 3.6 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ15853.1 - 0.079 13.3 8.5 1.6 9.1 3.7 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 OAJ15853.1 - 7.2 7.1 10.7 2.2 8.7 4.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Cmc1 PF08583.10 OAJ15853.1 - 9.9 6.3 11.3 9.4 6.3 0.4 2.9 1 1 3 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like MFS_1 PF07690.16 OAJ15854.1 - 1e-38 133.2 31.4 2.3e-37 128.7 26.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 OAJ15854.1 - 0.01 15.6 1.5 0.4 10.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF697) STIL_N PF15253.6 OAJ15854.1 - 2 7.3 3.3 4.9 6.0 3.3 1.5 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus MCM PF00493.23 OAJ15855.1 - 1e-101 338.8 0.2 1.9e-101 337.9 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ15855.1 - 1e-37 128.8 1.1 1.9e-37 127.9 1.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAJ15855.1 - 3.7e-27 94.7 6.6 8.4e-27 93.5 6.6 1.7 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAJ15855.1 - 2.3e-26 92.0 2.4 1.2e-25 89.8 0.5 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ15855.1 - 8.9e-21 74.4 1.7 1.4e-20 73.8 0.5 2.1 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ15855.1 - 3.1e-07 30.0 0.0 2.5e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ15855.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ15855.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Succ_DH_flav_C PF02910.20 OAJ15855.1 - 0.026 14.5 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term AAA_5 PF07728.14 OAJ15855.1 - 0.035 14.1 0.0 0.084 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.14 OAJ15855.1 - 0.048 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain LigB PF02900.18 OAJ15856.1 - 1.9e-17 63.3 0.0 1.2e-11 44.3 0.1 2.2 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.12 OAJ15856.1 - 0.052 13.6 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease Band_7 PF01145.25 OAJ15857.1 - 2.8e-24 86.1 4.5 6.2e-24 85.0 4.5 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAJ15857.1 - 0.00033 19.8 1.4 0.00043 19.5 1.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial SRF-TF PF00319.18 OAJ15857.1 - 0.038 13.5 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Vma12 PF11712.8 OAJ15858.1 - 1.9e-30 105.7 0.3 3e-30 105.1 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.9 OAJ15858.1 - 4.9e-11 42.4 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain PA_decarbox PF05870.11 OAJ15858.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Oxidored_q2 PF00420.24 OAJ15858.1 - 1.6 8.4 4.1 46 3.7 0.8 2.9 2 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pkinase PF00069.25 OAJ15860.1 - 5.4e-40 137.4 0.1 4.3e-21 75.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15860.1 - 1.7e-11 43.9 0.4 2.1e-08 33.8 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Roughex PF06020.11 OAJ15860.1 - 3.4 6.7 9.7 6.2 5.8 9.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein ArfGap PF01412.18 OAJ15861.1 - 3.5e-32 110.9 0.1 8.3e-32 109.7 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf p450 PF00067.22 OAJ15862.1 - 4.3e-73 246.6 0.0 1.8e-45 155.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3605 PF12239.8 OAJ15863.1 - 8.8e-23 81.3 0.1 8.6e-18 65.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) SUZ PF12752.7 OAJ15863.1 - 0.13 13.1 6.4 0.65 10.8 5.5 2.6 2 1 0 2 2 2 0 SUZ domain DUF4512 PF14975.6 OAJ15863.1 - 0.23 12.3 0.9 0.55 11.1 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SR-25 PF10500.9 OAJ15863.1 - 8.5 5.9 12.9 16 5.0 12.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aminotran_5 PF00266.19 OAJ15864.1 - 1e-19 70.7 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ15864.1 - 1.1e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GGACT PF06094.12 OAJ15865.1 - 1.1e-11 45.4 0.0 1.8e-11 44.7 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Lon_C PF05362.13 OAJ15866.1 - 1.1e-64 217.8 0.1 2.3e-64 216.7 0.1 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 OAJ15866.1 - 6e-23 81.7 0.0 1.3e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ15866.1 - 5.2e-10 39.5 0.0 1e-08 35.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAJ15866.1 - 4e-08 33.1 0.0 8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON_substr_bdg PF02190.16 OAJ15866.1 - 1.1e-06 28.7 0.0 4.5e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_16 PF13191.6 OAJ15866.1 - 3.5e-06 27.5 0.5 2.3e-05 24.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ15866.1 - 0.00014 22.2 0.1 0.011 16.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ15866.1 - 0.00076 19.6 0.0 0.0036 17.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAJ15866.1 - 0.0055 16.5 0.1 0.022 14.5 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAJ15866.1 - 0.0084 16.3 0.1 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAJ15866.1 - 0.021 14.2 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAJ15866.1 - 0.022 15.3 0.0 0.061 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ15866.1 - 0.027 14.2 0.0 0.076 12.7 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein TniB PF05621.11 OAJ15866.1 - 0.028 13.8 0.1 5 6.5 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein AAA_PrkA PF08298.11 OAJ15866.1 - 0.029 13.3 0.0 0.59 9.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain RNA_helicase PF00910.22 OAJ15866.1 - 0.036 14.5 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 OAJ15866.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAJ15866.1 - 0.061 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ15866.1 - 0.072 13.0 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAJ15866.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain GREB1 PF15782.5 OAJ15866.1 - 0.2 8.8 0.0 0.3 8.2 0.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_23 PF13476.6 OAJ15866.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.7 2 2 1 3 3 3 0 AAA domain NUDIX PF00293.28 OAJ15867.1 - 2.6e-10 40.5 0.0 5.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF2456 PF10445.9 OAJ15868.1 - 3.1e-18 65.6 3.5 3.1e-18 65.6 3.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) Sporozoite_P67 PF05642.11 OAJ15869.1 - 4.3 5.3 11.8 9.6 4.2 11.8 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Collagen PF01391.18 OAJ15879.1 - 1.1e-13 50.7 130.4 1.7e-07 30.9 39.5 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 OAJ15880.1 - 1.4e-18 66.4 72.6 2.4e-08 33.6 28.2 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) ArsA_ATPase PF02374.15 OAJ15881.1 - 1e-108 363.1 0.0 1.2e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAJ15881.1 - 7.9e-12 45.4 0.2 2.1e-11 44.0 0.1 1.7 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OAJ15881.1 - 1.4e-10 41.3 0.0 2.5e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OAJ15881.1 - 2.4e-05 23.9 0.5 0.00044 19.8 0.1 2.3 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 OAJ15881.1 - 3e-05 23.6 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OAJ15881.1 - 6e-05 22.6 0.0 0.00015 21.3 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OAJ15881.1 - 0.00064 19.4 0.4 0.0053 16.4 0.2 2.2 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 OAJ15881.1 - 0.0063 17.0 0.0 0.052 14.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ15881.1 - 0.0066 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 OAJ15881.1 - 0.0083 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 OAJ15881.1 - 0.052 13.3 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ15881.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.14 OAJ15881.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Alba PF01918.21 OAJ15884.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Alba Glyco_tranf_2_3 PF13641.6 OAJ15885.1 - 2e-18 67.1 0.0 3.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ15885.1 - 3.1e-16 59.9 6.9 3.1e-16 59.9 6.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ15885.1 - 5.1e-06 26.1 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ15885.1 - 3.9e-05 23.5 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Wzy_C_2 PF11846.8 OAJ15885.1 - 0.19 11.7 3.4 2.7 7.9 0.2 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal Claudin_2 PF13903.6 OAJ15885.1 - 0.72 9.6 8.9 0.047 13.4 2.2 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2178 PF09946.9 OAJ15886.1 - 0.049 13.8 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) Holin_BhlA PF10960.8 OAJ15886.1 - 0.063 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 BhlA holin family PSI PF01437.25 OAJ15887.1 - 2.6 8.7 20.7 0.73 10.4 6.7 2.6 2 0 0 2 2 2 0 Plexin repeat RRM_1 PF00076.22 OAJ15888.1 - 8.1e-57 189.0 0.0 2.2e-18 65.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ15888.1 - 2.5e-06 27.5 0.0 0.57 10.3 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif RRM_5 PF13893.6 OAJ15888.1 - 0.0055 16.3 0.0 0.56 9.8 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3344 PF11824.8 OAJ15888.1 - 0.0092 15.6 0.3 0.045 13.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3344) ATP-grasp_2 PF08442.10 OAJ15888.1 - 0.014 15.0 0.0 2.7 7.5 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain DUF3343 PF11823.8 OAJ15888.1 - 0.028 13.9 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Macoilin PF09726.9 OAJ15888.1 - 1.2 7.6 16.7 1.6 7.2 16.7 1.1 1 0 0 1 1 1 0 Macoilin family CD99L2 PF12301.8 OAJ15888.1 - 8.9 6.6 10.8 16 5.7 10.3 1.7 1 1 0 1 1 1 0 CD99 antigen like protein 2 Glyco_hydro_30 PF02055.16 OAJ15889.1 - 8.6e-17 61.1 1.4 6e-16 58.4 1.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAJ15889.1 - 3.6e-05 23.2 0.1 6.7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 DUF2937 PF11157.8 OAJ15890.1 - 0.0033 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) PRKCSH PF07915.13 OAJ15891.1 - 1.8e-11 44.9 0.0 6.7e-09 36.6 0.0 2.8 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein DUF3684 PF12449.8 OAJ15891.1 - 0.1 10.3 0.5 0.16 9.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) HlyIII PF03006.20 OAJ15908.1 - 8.7e-57 192.4 21.4 2.3e-56 191.0 21.4 1.7 1 1 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.15 OAJ15908.1 - 0.18 12.1 3.0 0.16 12.3 0.6 2.2 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Pkinase PF00069.25 OAJ15909.1 - 4.5e-22 78.7 0.0 7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15909.1 - 1.2e-10 41.1 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBP1_TM PF14812.6 OAJ15910.1 - 0.012 16.0 22.4 0.023 15.1 3.3 3.5 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dicty_REP PF05086.12 OAJ15910.1 - 0.1 10.6 4.5 0.15 10.0 4.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PGM_PMM_IV PF00408.20 OAJ15910.1 - 0.11 12.7 0.1 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain SNF2_N PF00176.23 OAJ15911.1 - 8e-58 195.8 0.4 7.3e-57 192.7 0.4 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 OAJ15911.1 - 6.5e-11 41.9 5.1 1.2e-10 41.0 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAJ15911.1 - 2.1e-10 41.0 0.0 1.2e-09 38.5 0.0 2.4 3 1 0 3 3 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OAJ15911.1 - 9e-09 35.1 5.7 1.6e-08 34.2 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ15911.1 - 2e-07 30.9 8.1 4.4e-07 29.8 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ15911.1 - 2.4e-07 31.0 5.5 4.3e-07 30.2 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ15911.1 - 2e-06 27.8 7.8 3.8e-06 27.0 7.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAJ15911.1 - 4e-06 26.6 2.7 7.3e-06 25.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15911.1 - 0.00019 21.2 4.2 0.00034 20.4 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ15911.1 - 0.00037 20.4 3.2 0.00071 19.5 3.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ15911.1 - 0.00042 20.5 3.2 0.0014 18.9 3.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAJ15911.1 - 0.1 12.5 3.1 0.24 11.3 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OAJ15911.1 - 0.41 10.4 7.0 0.78 9.5 7.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OAJ15911.1 - 0.43 10.7 2.1 0.96 9.6 2.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Dimer_Tnp_hAT PF05699.14 OAJ15912.1 - 2.5e-16 59.2 0.0 4.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF2457 PF10446.9 OAJ15912.1 - 0.16 11.1 13.1 0.28 10.3 13.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MSA-2c PF12238.8 OAJ15912.1 - 0.48 10.4 6.9 1.1 9.3 6.9 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c CCDC53 PF10152.9 OAJ15912.1 - 0.65 10.4 3.8 3.3 8.1 0.8 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SDA1 PF05285.12 OAJ15912.1 - 3.6 6.9 7.7 5.2 6.4 7.7 1.2 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.6 OAJ15912.1 - 9.5 6.7 9.3 28 5.2 9.3 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SMC_N PF02463.19 OAJ15914.1 - 3.3e-69 232.7 1.5 4.7e-69 232.2 1.5 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ15914.1 - 1.2e-28 99.7 0.1 4.2e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ15914.1 - 1.3e-18 68.2 10.3 1.3e-18 68.2 10.3 6.8 2 2 3 6 6 6 1 AAA domain AAA_15 PF13175.6 OAJ15914.1 - 5.6e-18 65.8 28.4 5.7e-15 55.9 4.8 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 OAJ15914.1 - 3e-12 47.0 13.7 2.3e-06 27.6 2.1 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ15914.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ15914.1 - 0.21 10.9 0.0 0.21 10.9 0.0 3.5 3 1 0 3 3 3 0 FtsK/SpoIIIE family Cation_ATPase_N PF00690.26 OAJ15914.1 - 7.7 6.3 5.8 2 8.1 0.6 2.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Glyco_trans_1_2 PF13524.6 OAJ15914.1 - 7.8 7.0 7.6 1.4 9.4 2.0 2.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 FGGY_C PF02782.16 OAJ15916.1 - 2.4e-45 154.7 0.1 3.8e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAJ15916.1 - 1e-22 80.9 0.0 6.3e-22 78.3 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAJ15916.1 - 2.9e-05 23.7 0.2 8.1e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 OAJ15916.1 - 0.0016 18.4 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 Hexokinase ROK PF00480.20 OAJ15916.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ROK family Carbpep_Y_N PF05388.11 OAJ15916.1 - 0.13 12.8 0.3 4.6 7.8 0.2 2.6 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Tam41_Mmp37 PF09139.11 OAJ15917.1 - 6.2e-105 351.2 0.0 7.9e-105 350.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Seryl_tRNA_N PF02403.22 OAJ15929.1 - 0.0044 17.2 4.6 0.0065 16.7 4.6 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.6 OAJ15929.1 - 0.025 15.0 2.4 0.037 14.5 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) PI3K_P85_iSH2 PF16454.5 OAJ15929.1 - 0.051 13.2 1.1 0.074 12.6 1.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ZapB PF06005.12 OAJ15929.1 - 1.1 9.7 6.3 5.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF5320 PF17253.2 OAJ15929.1 - 1.5 9.9 4.5 69 4.6 4.4 2.2 1 1 0 1 1 1 0 Family of unknown function (DUF5320) DivIC PF04977.15 OAJ15929.1 - 1.6 8.6 8.8 7.5 6.4 0.8 2.3 1 1 0 2 2 2 0 Septum formation initiator Ribosomal_L24e PF01246.20 OAJ15930.1 - 2.3e-31 107.8 5.9 2.3e-31 107.8 5.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Defensin_5 PF18251.1 OAJ15930.1 - 0.028 14.5 0.3 0.06 13.4 0.3 1.4 1 0 0 1 1 1 0 Fungal defensin Copsin Flu_M1 PF00598.19 OAJ15930.1 - 0.049 13.1 0.2 0.077 12.5 0.2 1.4 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Terminase_3C PF17288.2 OAJ15930.1 - 0.065 13.6 1.0 0.083 13.3 1.0 1.3 1 0 0 1 1 1 0 Terminase RNAseH like domain HAGH_C PF16123.5 OAJ15930.1 - 0.071 13.6 0.8 0.071 13.6 0.8 2.1 1 1 0 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus NDC10_II PF16787.5 OAJ15931.1 - 1.3e-40 139.4 0.0 1.8e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ15931.1 - 0.0017 18.6 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_23 PF13384.6 OAJ15931.1 - 0.13 12.1 0.4 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 OAJ15931.1 - 0.3 11.2 2.1 0.92 9.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain SURF6 PF04935.12 OAJ15934.1 - 2.1e-33 115.8 46.6 2.1e-33 115.8 46.6 3.5 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 OAJ15934.1 - 2.6e-14 53.5 3.5 2.6e-14 53.5 3.5 5.4 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 WD40 PF00400.32 OAJ15935.1 - 4.5e-58 191.9 27.7 8.5e-09 35.9 0.0 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15935.1 - 1.2e-16 60.8 1.9 0.00099 19.4 0.0 5.1 3 2 2 5 5 4 3 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 OAJ15935.1 - 0.0002 20.9 0.2 0.32 10.7 0.1 3.2 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature eIF2A PF08662.11 OAJ15935.1 - 0.00021 21.2 0.0 0.0075 16.2 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 OAJ15935.1 - 0.00029 21.3 0.0 0.0007 20.1 0.0 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 OAJ15935.1 - 0.00058 18.9 0.0 0.14 11.1 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAJ15935.1 - 0.0018 17.1 1.1 1.8 7.3 0.1 4.0 4 1 1 5 5 5 1 Nup133 N terminal like Nup160 PF11715.8 OAJ15935.1 - 0.0025 16.5 3.8 4 6.0 0.0 4.5 3 2 1 5 5 5 1 Nucleoporin Nup120/160 IBB PF01749.20 OAJ15935.1 - 0.0037 17.7 2.2 0.011 16.1 2.2 1.8 1 0 0 1 1 1 1 Importin beta binding domain MqsA_antitoxin PF15731.5 OAJ15935.1 - 0.013 15.6 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA IKI3 PF04762.12 OAJ15935.1 - 0.028 12.4 0.3 0.082 10.9 0.1 1.8 2 0 0 2 2 2 0 IKI3 family Nbas_N PF15492.6 OAJ15935.1 - 0.068 12.5 1.9 3.4 6.9 0.0 3.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Sin_N PF04801.13 OAJ15935.1 - 9.7 5.3 9.2 1.7 7.8 4.3 2.1 3 0 0 3 3 3 0 Sin-like protein conserved region Tropomyosin_1 PF12718.7 OAJ15936.1 - 0.00015 21.9 12.0 0.00015 21.9 12.0 16.6 1 1 16 18 18 18 4 Tropomyosin like Ceramidase_alk PF04734.13 OAJ15937.1 - 6.4e-174 579.3 0.0 9.6e-173 575.4 0.0 2.4 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAJ15937.1 - 9.6e-37 126.4 0.1 1.6e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF4179 PF13786.6 OAJ15938.1 - 0.0094 16.4 0.5 5.1 7.6 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4179) BAF1_ABF1 PF04684.13 OAJ15938.1 - 0.28 10.2 15.4 0.0083 15.2 2.8 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PMT PF02366.18 OAJ15940.1 - 1.7e-79 266.9 14.1 3.2e-79 266.0 14.1 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ15940.1 - 8.1e-61 205.1 0.3 8.1e-61 205.1 0.3 3.0 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ15940.1 - 1.2e-12 48.1 1.2 2.3e-12 47.2 0.7 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 OAJ15940.1 - 8.1e-06 26.1 9.8 8.1e-06 26.1 9.8 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 OAJ15941.1 - 3e-39 132.3 13.6 2.7e-07 31.1 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15941.1 - 7.2e-16 58.3 0.3 2.9e-05 24.3 0.0 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OAJ15941.1 - 1.2e-13 50.3 3.5 2.3e-13 49.5 3.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 OAJ15941.1 - 1.7e-05 23.9 0.0 0.26 10.2 0.0 3.6 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 OAJ15941.1 - 3.3e-05 23.4 0.1 0.0067 15.8 0.0 3.3 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 OAJ15941.1 - 9.5e-05 21.9 0.0 0.03 13.7 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 OAJ15941.1 - 0.0077 14.9 0.3 0.48 9.0 0.0 3.2 4 0 0 4 4 4 1 Nucleoporin Nup120/160 UPF0029 PF01205.19 OAJ15953.1 - 3.3e-27 94.9 3.5 1.2e-26 93.1 0.0 3.4 3 1 0 3 3 3 1 Uncharacterized protein family UPF0029 PH PF00169.29 OAJ15953.1 - 1.7e-05 25.3 0.0 3.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PH domain RWD PF05773.22 OAJ15953.1 - 0.0027 18.0 0.1 0.014 15.6 0.1 2.1 1 1 0 1 1 1 1 RWD domain eIF3_subunit PF08597.10 OAJ15953.1 - 6.5 6.6 12.6 1.4 8.7 7.2 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Cadherin_C_2 PF16492.5 OAJ15954.1 - 1.8 9.4 3.8 8.2 7.3 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Shisa PF13908.6 OAJ15954.1 - 9 6.5 5.9 50 4.1 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DEAD PF00270.29 OAJ15955.1 - 2.4e-38 131.7 0.1 4.7e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ15955.1 - 2.8e-27 95.3 0.0 2.2e-25 89.1 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ15955.1 - 9e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ15955.1 - 0.029 13.7 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-RING_UBOX PF13445.6 OAJ15956.1 - 1.2e-07 31.6 2.8 1.2e-07 31.6 2.8 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ15956.1 - 3.7e-06 26.7 3.9 3.7e-06 26.7 3.9 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ15956.1 - 2.1e-05 24.3 4.8 2.1e-05 24.3 4.8 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ15956.1 - 5.6e-05 23.0 6.5 5.6e-05 23.0 6.5 2.7 2 2 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ15956.1 - 0.00036 20.6 5.1 0.00036 20.6 5.1 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 OAJ15956.1 - 0.0071 16.2 7.4 0.0071 16.2 7.4 3.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ15956.1 - 0.44 10.4 19.7 0.027 14.3 4.5 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAJ15956.1 - 0.57 10.6 23.4 0.07 13.5 12.8 3.2 2 1 0 2 2 2 0 Ring finger domain CTU2 PF10288.9 OAJ15956.1 - 1.9 8.8 9.1 1.8 8.8 0.8 3.5 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 Ribosomal_S26e PF01283.19 OAJ15958.1 - 4.8e-54 181.4 8.5 5.8e-54 181.1 8.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 OAJ15958.1 - 0.0051 17.4 1.6 0.0094 16.5 1.6 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAJ15958.1 - 0.0076 17.2 1.2 0.015 16.2 1.2 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OAJ15958.1 - 0.13 12.5 2.7 0.35 11.1 2.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.27 OAJ15958.1 - 0.76 9.7 4.8 0.25 11.2 1.1 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DPBB_1 PF03330.18 OAJ15959.1 - 9.2e-06 25.9 0.1 2.8e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ15959.1 - 6.6e-05 22.7 1.5 0.097 12.5 0.1 2.5 2 1 0 2 2 2 2 Barwin family ETF_QO PF05187.13 OAJ15960.1 - 6.5e-41 138.7 0.3 1.1e-40 138.0 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 OAJ15960.1 - 7.5e-08 31.9 0.2 7.7e-05 21.9 0.2 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ15960.1 - 9.6e-07 28.7 1.0 0.0014 18.3 0.3 2.6 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ15960.1 - 3.3e-06 27.2 0.0 1.2e-05 25.5 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ15960.1 - 0.00011 21.1 0.2 0.00017 20.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAJ15960.1 - 0.00011 21.5 0.1 0.00024 20.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ15960.1 - 0.00012 21.4 0.5 0.00024 20.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ15960.1 - 0.00022 20.6 0.0 0.0088 15.3 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAJ15960.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 OAJ15960.1 - 0.0045 17.6 1.1 0.01 16.4 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 OAJ15960.1 - 0.0071 16.9 0.2 0.58 10.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ15960.1 - 0.014 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ15960.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ15960.1 - 0.02 14.0 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_21 PF14697.6 OAJ15960.1 - 0.053 13.6 1.1 0.12 12.6 1.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 OAJ15960.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fer4_2 PF12797.7 OAJ15960.1 - 0.082 13.0 0.4 0.082 13.0 0.4 1.7 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 OAJ15960.1 - 1.8 8.8 4.2 0.84 9.8 0.7 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DUF1689 PF07954.11 OAJ15962.1 - 0.022 15.2 0.2 3 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Cys_Met_Meta_PP PF01053.20 OAJ15964.1 - 2.7e-53 180.9 0.0 1.3e-47 162.2 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ15964.1 - 0.034 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ15964.1 - 0.034 13.1 0.1 0.062 12.2 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class-V Hexokinase_2 PF03727.16 OAJ15966.1 - 1.1e-79 267.3 0.0 1.6e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAJ15966.1 - 5.6e-67 225.5 0.0 9.2e-67 224.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Ctr PF04145.15 OAJ15967.1 - 0.13 12.9 1.6 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 Ctr copper transporter family Epiglycanin_C PF14654.6 OAJ15967.1 - 0.18 11.9 2.6 0.14 12.3 0.5 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Methyltransf_16 PF10294.9 OAJ15968.1 - 1.1e-08 35.0 0.0 5.7e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAJ15968.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) EF1G PF00647.19 OAJ15977.1 - 1.1e-45 154.1 0.1 1.6e-45 153.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain LSM PF01423.22 OAJ15978.1 - 4.9e-22 77.4 0.1 5.6e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ15978.1 - 0.0019 18.3 0.0 0.0023 18.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain IGPS PF00218.21 OAJ15979.1 - 3.9e-83 278.5 0.0 2e-82 276.2 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 OAJ15979.1 - 8.4e-42 143.1 0.0 1.5e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 OAJ15979.1 - 6.4e-34 117.4 0.0 3.2e-29 102.1 0.0 2.4 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 OAJ15979.1 - 2.9e-06 27.2 0.2 8.1e-06 25.7 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 IMPDH PF00478.25 OAJ15979.1 - 1.2 8.1 6.7 1.5 7.7 0.1 3.4 4 0 0 4 4 4 0 IMP dehydrogenase / GMP reductase domain DUF89 PF01937.19 OAJ15980.1 - 4.7e-112 374.4 0.1 5.4e-112 374.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Vps23_core PF09454.10 OAJ15980.1 - 0.16 11.9 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Vps23 core domain PWI PF01480.17 OAJ15981.1 - 8.3e-09 35.6 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 OAJ15981.1 - 4e-07 29.8 2.5 7.8e-07 28.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ15981.1 - 0.00029 20.8 6.3 0.00053 19.9 6.3 1.5 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 OAJ15981.1 - 0.0007 19.6 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 OAJ15981.1 - 0.00086 19.1 0.1 0.0025 17.6 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 OAJ15981.1 - 0.0057 16.4 0.3 0.012 15.3 0.3 1.6 1 0 0 1 1 1 1 Calcipressin zf-CCCH_4 PF18044.1 OAJ15981.1 - 0.043 13.6 3.0 0.071 12.9 3.0 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Torus PF16131.5 OAJ15981.1 - 0.044 14.5 0.3 0.12 13.0 0.3 1.7 1 0 0 1 1 1 0 Torus domain RRM_3 PF08777.11 OAJ15981.1 - 0.052 13.6 2.4 0.14 12.3 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif zf-CCCH_2 PF14608.6 OAJ15981.1 - 0.88 10.1 2.7 1.6 9.3 2.7 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ASF1_hist_chap PF04729.13 OAJ15982.1 - 4.5e-61 205.3 0.6 1.2e-60 203.9 0.6 1.6 1 1 0 1 1 1 1 ASF1 like histone chaperone OrfB_Zn_ribbon PF07282.11 OAJ15983.1 - 9.1e-14 51.1 0.1 1.5e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 OAJ15983.1 - 0.00021 21.5 0.0 0.00038 20.7 0.0 1.4 1 0 0 1 1 1 1 Probable transposase Response_reg PF00072.24 OAJ15984.1 - 6.5e-22 77.8 0.1 5.5e-16 58.7 0.1 2.9 3 0 0 3 3 3 2 Response regulator receiver domain LrgB PF04172.16 OAJ15986.1 - 2.7e-35 121.9 10.0 2.7e-35 121.9 10.0 1.8 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 OAJ15986.1 - 0.011 15.7 0.7 0.011 15.7 0.7 4.0 3 1 1 4 4 4 0 LrgA family Nuc_sug_transp PF04142.15 OAJ15987.1 - 1.6e-06 27.5 0.1 2.4e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 OAJ15987.1 - 2.7e-05 24.3 2.5 2.7e-05 24.3 2.5 3.0 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 OAJ15987.1 - 3.3e-05 23.4 4.3 0.00012 21.5 0.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 OAJ15987.1 - 0.0031 16.8 4.0 0.26 10.5 4.0 2.3 1 1 0 1 1 1 1 UAA transporter family YihI PF04220.12 OAJ15987.1 - 0.15 11.8 0.6 0.25 11.1 0.6 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) MFS_2 PF13347.6 OAJ15988.1 - 2.6e-09 36.2 1.2 2.6e-09 36.2 1.2 2.8 3 1 0 3 3 3 1 MFS/sugar transport protein DUF1980 PF09323.10 OAJ15988.1 - 0.021 14.8 0.0 0.18 11.7 0.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) SelR PF01641.18 OAJ15989.1 - 2.1e-51 173.0 0.1 2.8e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 OAJ15989.1 - 0.091 12.9 3.1 0.1 12.7 0.4 2.4 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RTA1 PF04479.13 OAJ15990.1 - 1.7e-40 138.9 7.8 1.7e-40 138.9 7.8 1.7 1 1 1 2 2 2 1 RTA1 like protein DHHC PF01529.20 OAJ15990.1 - 5.4 7.1 11.3 4.7 7.3 3.3 2.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase EF1G PF00647.19 OAJ15991.1 - 1.2e-27 96.1 0.0 1.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OAJ15991.1 - 7.8e-15 55.0 0.5 5.2e-14 52.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ15991.1 - 1.9e-10 40.8 0.0 5.4e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ15991.1 - 2.6e-08 33.8 0.0 5.1e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ15991.1 - 1.1e-07 31.9 0.1 4e-07 30.2 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ15991.1 - 3.1e-07 30.7 0.0 6.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ15991.1 - 6.3e-05 23.2 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAJ15991.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 OAJ15991.1 - 3.5 8.3 7.1 6.9 7.3 7.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.19 OAJ15991.1 - 5.7 7.6 10.7 11 6.7 10.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein EF1G PF00647.19 OAJ15992.1 - 1.4e-47 160.2 0.2 2.5e-47 159.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 OAJ15992.1 - 2.4e-13 50.1 0.0 6.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAJ15992.1 - 1.4e-12 47.7 0.2 8.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ15992.1 - 7.4e-09 35.7 0.1 2.1e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ15992.1 - 2.8e-08 33.7 0.0 5.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ15992.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAJ15992.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ15992.1 - 0.08 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EF-hand_1 PF00036.32 OAJ15993.1 - 2.9e-25 85.9 13.1 3.3e-08 32.5 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ15993.1 - 1.2e-18 65.4 8.5 0.00023 20.9 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OAJ15993.1 - 5.5e-18 65.2 9.0 3.3e-13 49.9 2.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ15993.1 - 1.1e-15 56.3 14.1 4.6e-06 25.9 1.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OAJ15993.1 - 2.7e-10 39.9 14.4 0.004 17.0 1.8 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 OAJ15993.1 - 5.6e-05 23.0 5.8 0.0052 16.7 0.8 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ15993.1 - 0.0025 18.1 0.1 0.24 11.8 0.2 2.7 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ15993.1 - 0.0035 17.7 0.1 0.016 15.5 0.1 2.0 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.6 OAJ15993.1 - 0.052 14.2 0.5 10 6.8 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HSCB_C PF07743.13 OAJ15994.1 - 6.8e-17 61.7 1.6 6.8e-17 61.7 1.6 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAJ15994.1 - 3.5e-08 33.5 0.0 7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RNA_pol_Rpc34 PF05158.12 OAJ15994.1 - 0.038 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit CCDC-167 PF15188.6 OAJ15994.1 - 0.062 13.6 0.7 0.13 12.6 0.7 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 cwf21 PF08312.12 OAJ15994.1 - 0.38 10.9 8.3 0.27 11.4 4.4 2.3 2 0 0 2 2 2 0 cwf21 domain SLT_L PF14718.6 OAJ15994.1 - 5.3 7.2 7.0 35 4.6 0.5 3.3 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain EF_assoc_2 PF08356.12 OAJ16010.1 - 4.1e-25 87.6 0.0 4.1e-24 84.4 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 OAJ16010.1 - 1.2e-21 76.1 2.5 3.1e-21 74.8 1.0 2.4 2 1 0 2 2 2 1 EF hand associated Ras PF00071.22 OAJ16010.1 - 1.2e-15 57.5 0.0 0.0011 18.6 0.0 4.9 4 1 0 4 4 4 3 Ras family Roc PF08477.13 OAJ16010.1 - 6.6e-07 29.6 0.0 0.02 15.1 0.0 4.4 4 1 0 4 4 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ16010.1 - 7.2e-07 29.3 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 OAJ16010.1 - 1.1e-06 29.0 3.2 0.024 15.1 0.1 2.7 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAJ16010.1 - 1.6e-05 24.1 2.1 0.056 13.0 0.1 2.7 2 0 0 2 2 2 2 EF hand RsgA_GTPase PF03193.16 OAJ16010.1 - 2.6e-05 24.2 0.2 0.0064 16.4 0.0 3.6 4 0 0 4 4 4 1 RsgA GTPase AAA_22 PF13401.6 OAJ16010.1 - 2.7e-05 24.5 0.1 0.28 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain EF-hand_6 PF13405.6 OAJ16010.1 - 3.2e-05 23.5 4.3 0.013 15.4 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 OAJ16010.1 - 5.8e-05 23.5 0.1 0.12 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 OAJ16010.1 - 0.00012 22.5 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 OAJ16010.1 - 0.00098 19.1 0.2 0.97 9.3 0.0 2.4 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 OAJ16010.1 - 0.0016 18.5 0.8 1.1 9.3 0.0 2.7 3 0 0 3 3 2 1 Dynamin family AIG1 PF04548.16 OAJ16010.1 - 0.0039 16.5 0.1 0.007 15.7 0.1 1.3 1 0 0 1 1 1 1 AIG1 family AAA_29 PF13555.6 OAJ16010.1 - 0.0062 16.3 4.3 0.12 12.1 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 OAJ16010.1 - 0.011 15.5 0.0 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 OAJ16010.1 - 0.014 14.8 2.7 0.042 13.4 0.1 2.4 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.6 OAJ16010.1 - 0.033 14.7 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 OAJ16010.1 - 0.034 14.6 0.0 3.9 7.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 OAJ16010.1 - 0.04 14.2 0.1 6 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ16010.1 - 0.048 13.4 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ16010.1 - 0.078 12.5 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ16010.1 - 0.082 13.3 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 OAJ16010.1 - 0.093 12.5 0.1 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.18 OAJ16010.1 - 0.099 11.9 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Septin cobW PF02492.19 OAJ16010.1 - 0.17 11.5 0.0 11 5.6 0.0 2.8 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAJ16010.1 - 0.19 11.9 3.2 4 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 OAJ16010.1 - 0.25 11.8 0.3 22 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAJ16010.1 - 0.28 11.1 0.0 1.3 8.9 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea EF-hand_10 PF14788.6 OAJ16010.1 - 0.39 10.6 1.4 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 EF hand Cyclin PF08613.11 OAJ16011.1 - 1.4e-06 28.7 0.0 6.1e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Cyclin Prefoldin_2 PF01920.20 OAJ16012.1 - 3.8e-22 78.3 1.9 4.5e-22 78.0 1.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 OAJ16012.1 - 5.1e-05 23.0 3.4 0.021 14.6 0.1 2.2 1 1 1 2 2 2 2 Septum formation initiator ADIP PF11559.8 OAJ16012.1 - 0.0022 18.1 1.4 0.56 10.3 0.0 2.2 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding SesA PF17107.5 OAJ16012.1 - 0.0087 16.2 2.1 0.73 10.0 0.3 2.2 1 1 1 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases Yuri_gagarin PF15934.5 OAJ16012.1 - 0.021 14.7 3.8 0.025 14.4 3.8 1.1 1 0 0 1 1 1 0 Yuri gagarin PI3K_P85_iSH2 PF16454.5 OAJ16012.1 - 0.022 14.4 2.8 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4164 PF13747.6 OAJ16012.1 - 0.024 14.9 6.9 0.28 11.5 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Spc24 PF08286.11 OAJ16012.1 - 0.11 12.8 4.8 4.4 7.6 1.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1664 PF07889.12 OAJ16012.1 - 0.2 11.7 1.9 1.7 8.7 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 OAJ16012.1 - 0.21 11.7 5.4 4.8 7.3 0.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Ras PF00071.22 OAJ16013.1 - 6.3e-62 208.0 0.1 7.4e-62 207.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ16013.1 - 1.1e-33 116.0 0.0 1.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ16013.1 - 2.4e-12 46.7 0.0 3.3e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ16013.1 - 6e-06 26.3 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ16013.1 - 0.00017 21.2 0.1 0.00087 18.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ16013.1 - 0.0021 18.0 0.1 0.19 11.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ16013.1 - 0.0036 17.6 0.1 0.053 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ16013.1 - 0.004 17.6 0.1 0.0065 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OAJ16013.1 - 0.0061 16.0 0.0 0.011 15.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ16013.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAJ16013.1 - 0.026 14.3 0.0 0.084 12.6 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 OAJ16013.1 - 0.039 14.2 0.2 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAJ16013.1 - 0.043 14.3 0.1 0.094 13.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 OAJ16013.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ16013.1 - 0.067 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAJ16013.1 - 0.069 12.5 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 OAJ16013.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 OAJ16013.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 OAJ16013.1 - 0.088 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TACC_C PF05010.14 OAJ16014.1 - 4 7.2 9.5 6.4 6.5 9.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Zn_clus PF00172.18 OAJ16015.1 - 9.2e-07 28.9 3.7 1.7e-06 28.0 3.7 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ16015.1 - 0.00083 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain AHJR-like PF18743.1 OAJ16015.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 REase_AHJR-like CoA_binding PF02629.19 OAJ16016.1 - 2.5e-29 101.8 3.3 5.8e-29 100.6 0.2 2.5 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAJ16016.1 - 9.1e-20 71.0 0.5 1.5e-19 70.3 0.5 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAJ16016.1 - 1.7e-09 37.6 0.0 4.1e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 OAJ16016.1 - 3.6e-05 24.2 0.0 0.00028 21.3 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 OAJ16016.1 - 0.053 14.3 0.0 0.19 12.5 0.0 1.9 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Lipase_3 PF01764.25 OAJ16019.1 - 6.5e-12 45.5 0.0 6.5e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) PsaL PF02605.15 OAJ16019.1 - 0.0028 17.3 0.1 0.0081 15.8 0.0 1.8 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI Mito_carr PF00153.27 OAJ16021.1 - 2.2e-48 162.1 6.2 5.9e-16 58.2 0.0 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein Macoilin PF09726.9 OAJ16021.1 - 0.52 8.8 4.0 0.64 8.5 4.0 1.1 1 0 0 1 1 1 0 Macoilin family Adeno_PV PF03910.13 OAJ16021.1 - 9.2 4.9 10.0 15 4.2 10.0 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF3844 PF12955.7 OAJ16022.1 - 3.4e-26 91.4 0.1 5.8e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Internalin_N PF12354.8 OAJ16022.1 - 3.5 7.8 5.0 2.2 8.4 0.8 2.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal DPBB_1 PF03330.18 OAJ16023.1 - 5.4e-06 26.6 0.0 9.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ16023.1 - 0.0013 18.6 0.2 0.0022 17.8 0.2 1.3 1 0 0 1 1 1 1 Barwin family Tom6 PF17112.5 OAJ16024.1 - 0.093 12.2 0.6 0.17 11.4 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom6, fungal Syntaxin-6_N PF09177.11 OAJ16025.1 - 2.5e-17 63.2 2.2 2.7e-16 59.9 0.0 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF4407 PF14362.6 OAJ16025.1 - 5.2e-05 22.8 0.1 9.5e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) FliJ PF02050.16 OAJ16025.1 - 0.0002 21.6 6.0 0.012 15.9 2.5 2.5 2 1 1 3 3 3 1 Flagellar FliJ protein Use1 PF09753.9 OAJ16025.1 - 0.00027 20.7 0.1 0.00074 19.3 0.1 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 HisKA_3 PF07730.13 OAJ16025.1 - 0.0027 18.2 5.4 0.17 12.4 0.2 2.5 2 0 0 2 2 2 2 Histidine kinase DUF1664 PF07889.12 OAJ16025.1 - 0.0091 16.0 1.5 1.9 8.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF5082 PF16888.5 OAJ16025.1 - 0.013 15.8 1.5 1 9.7 0.3 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 OAJ16025.1 - 0.016 14.6 2.1 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2046 PF09755.9 OAJ16025.1 - 0.032 13.5 2.4 2.9 7.0 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) TPR_MLP1_2 PF07926.12 OAJ16025.1 - 0.035 14.1 5.7 1 9.4 3.3 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 OAJ16025.1 - 0.036 13.9 8.8 0.31 10.9 0.4 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAJ16025.1 - 0.039 14.6 5.2 0.069 13.8 0.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GARP PF16731.5 OAJ16025.1 - 0.071 12.8 2.7 0.13 12.0 0.3 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma UPF0242 PF06785.11 OAJ16025.1 - 0.076 13.1 3.1 0.087 12.9 1.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ApoLp-III PF07464.11 OAJ16025.1 - 0.082 13.0 0.2 4.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2959 PF11172.8 OAJ16025.1 - 0.097 12.8 1.0 2.2 8.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF848 PF05852.11 OAJ16025.1 - 0.11 12.6 3.2 2.3 8.3 1.7 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3584 PF12128.8 OAJ16025.1 - 0.12 9.9 2.4 0.33 8.4 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) LPP PF04728.13 OAJ16025.1 - 0.13 12.7 2.5 2.1 8.8 0.1 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper AIP3 PF03915.13 OAJ16025.1 - 0.14 11.2 1.5 0.74 8.8 0.2 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 CENP-H PF05837.12 OAJ16025.1 - 0.17 12.3 2.5 12 6.4 0.0 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Golgin_A5 PF09787.9 OAJ16025.1 - 0.19 11.2 4.6 4 6.8 0.0 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 OAJ16025.1 - 0.23 11.9 3.4 16 5.9 0.0 3.5 3 2 1 4 4 2 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 OAJ16025.1 - 0.4 11.1 4.7 0.83 10.1 1.7 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF745 PF05335.13 OAJ16025.1 - 0.41 10.4 4.5 16 5.1 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HXXSHH PF07586.11 OAJ16025.1 - 0.49 9.9 4.9 0.25 10.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) SNARE PF05739.19 OAJ16025.1 - 0.49 10.4 18.3 0.17 11.9 9.4 3.5 3 1 0 3 3 3 0 SNARE domain DUF4164 PF13747.6 OAJ16025.1 - 0.78 10.1 5.4 3.3 8.0 0.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) Spc7 PF08317.11 OAJ16025.1 - 0.98 8.2 4.1 5.9 5.7 2.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 OAJ16025.1 - 1.6 9.3 9.0 2.8 8.4 4.3 2.8 3 1 0 3 3 2 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 OAJ16025.1 - 1.6 8.7 5.1 14 5.7 1.2 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cue1_U7BR PF18499.1 OAJ16026.1 - 0.0016 18.4 1.0 0.0031 17.5 1.0 1.4 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 G2BR PF18442.1 OAJ16026.1 - 0.0047 16.5 4.8 0.0088 15.7 4.8 1.4 1 0 0 1 1 1 1 E3 gp78 Ube2g2-binding region (G2BR) G10 PF01125.17 OAJ16027.1 - 1.1e-66 223.1 5.4 1.2e-66 222.9 5.4 1.0 1 0 0 1 1 1 1 G10 protein PhoLip_ATPase_C PF16212.5 OAJ16035.1 - 3e-74 249.9 22.0 6.5e-74 248.8 22.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ16035.1 - 2.3e-26 91.3 2.9 5.2e-26 90.1 2.9 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ16035.1 - 2.2e-12 46.9 0.0 9.9e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ16035.1 - 8.2e-12 45.9 1.4 5e-07 30.2 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ16035.1 - 1.8e-05 24.4 0.0 0.00018 21.1 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ16035.1 - 0.0034 17.2 0.1 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 OAJ16035.1 - 0.14 12.4 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III psi subunit EBP PF05241.12 OAJ16036.1 - 0.056 12.9 8.1 0.27 10.7 8.1 2.0 1 1 0 1 1 1 0 Emopamil binding protein Ribosomal_L37ae PF01780.19 OAJ16037.1 - 3.8e-40 135.8 8.5 4.3e-40 135.7 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAJ16037.1 - 0.0013 18.8 0.9 0.0018 18.4 0.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OAJ16037.1 - 0.0047 16.9 2.2 0.0076 16.2 2.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 OAJ16037.1 - 0.0078 16.2 4.6 0.25 11.4 0.4 2.2 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.6 OAJ16037.1 - 0.039 14.4 5.1 0.26 11.8 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain VPS13_mid_rpt PF16910.5 OAJ16038.1 - 1.8e-94 315.6 10.9 9.8e-93 309.9 2.8 4.9 4 0 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 OAJ16038.1 - 4.8e-84 282.0 0.0 6.2e-80 268.4 0.0 4.0 4 0 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OAJ16038.1 - 1.4e-82 277.0 5.8 9.4e-80 267.8 0.5 3.6 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAJ16038.1 - 1.1e-75 253.3 3.5 6.2e-70 234.6 0.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAJ16038.1 - 2.2e-40 137.4 0.1 1.7e-39 134.5 0.0 2.7 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAJ16038.1 - 9.4e-10 38.7 0.4 3.1e-08 33.8 0.0 3.3 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain BTB PF00651.31 OAJ16039.1 - 0.0075 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain RNB PF00773.19 OAJ16040.1 - 2.7e-93 312.9 0.0 3.6e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 OAJ16040.1 - 2.4e-25 89.0 0.0 4.7e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAJ16040.1 - 6.7e-20 70.9 0.1 1.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 OAJ16040.1 - 1.2e-17 63.6 0.0 2.7e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 OAJ16040.1 - 6.1e-08 33.0 0.0 2.2e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 PIN domain CSD2 PF17876.1 OAJ16040.1 - 4e-07 30.1 0.0 0.00018 21.6 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain GCH_III PF05165.12 OAJ16041.1 - 0.25 10.6 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase III Nup192 PF11894.8 OAJ16042.1 - 9.2e-221 735.8 1.6 1.3e-220 735.4 1.6 1.2 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DNA_pol_phi PF04931.13 OAJ16042.1 - 0.13 10.4 0.2 0.41 8.7 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase phi Sec8_exocyst PF04048.14 OAJ16043.1 - 2.8e-34 118.0 0.2 7.1e-34 116.7 0.2 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 OAJ16043.1 - 0.0011 19.1 0.2 0.0087 16.2 0.1 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 OAJ16043.1 - 0.0011 18.3 0.3 0.0028 17.0 0.3 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex NAD_binding_10 PF13460.6 OAJ16043.1 - 0.0062 16.4 1.1 0.47 10.3 0.1 3.3 3 0 0 3 3 3 1 NAD(P)H-binding Zw10 PF06248.13 OAJ16043.1 - 0.022 13.3 0.2 0.037 12.6 0.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 NolV PF06635.12 OAJ16043.1 - 0.071 12.5 0.4 0.14 11.5 0.4 1.4 1 0 0 1 1 1 0 Nodulation protein NolV eIF2A PF08662.11 OAJ16044.1 - 2.6e-82 275.4 0.1 4.3e-80 268.2 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAJ16044.1 - 8.6e-05 23.2 0.3 0.69 10.9 0.2 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat IATP PF04568.12 OAJ16044.1 - 0.25 11.8 1.4 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Proteasome_A_N PF10584.9 OAJ16044.1 - 0.44 10.3 4.0 15 5.4 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 OAJ16044.1 - 7.2 7.1 6.0 2.4 8.6 0.6 2.7 1 1 2 3 3 3 0 Carnitine deficiency-associated protein 3 Pkinase PF00069.25 OAJ16045.1 - 2.6e-63 213.9 0.0 3.1e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16045.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ16045.1 - 3.9e-07 30.2 0.1 2.6e-05 24.3 0.3 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ16045.1 - 0.0073 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAJ16045.1 - 0.018 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 OAJ16045.1 - 0.019 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OAJ16045.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PAP2_3 PF14378.6 OAJ16047.1 - 4.4e-22 78.7 16.1 4.4e-22 78.7 16.1 2.4 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 OAJ16047.1 - 3e-08 33.5 6.6 3e-08 33.5 6.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 OAJ16047.1 - 7.7 7.1 14.2 0.14 12.7 5.9 2.5 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF2236 PF09995.9 OAJ16061.1 - 1.6e-34 120.1 0.1 3.6e-34 119.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) FA_desaturase PF00487.24 OAJ16061.1 - 0.092 12.6 1.2 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Fatty acid desaturase SBF PF01758.16 OAJ16062.1 - 2.7e-42 144.7 14.8 2.7e-42 144.7 14.8 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Ank_3 PF13606.6 OAJ16063.1 - 0.17 12.6 0.1 0.93 10.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_UBOX PF13445.6 OAJ16064.1 - 1.7e-06 27.9 0.9 4.3e-06 26.6 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ16064.1 - 9.9e-06 25.3 0.6 9.9e-06 25.3 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ16064.1 - 7.2e-05 22.6 6.4 0.00028 20.7 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ16064.1 - 8e-05 22.4 2.0 8e-05 22.4 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ16064.1 - 0.00076 19.3 1.4 0.00076 19.3 1.4 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 OAJ16064.1 - 0.0013 18.7 3.2 0.006 16.5 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 OAJ16064.1 - 0.0032 17.8 8.3 0.0041 17.4 3.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ16064.1 - 0.0076 16.4 3.1 0.0076 16.4 3.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ16064.1 - 0.014 15.2 7.0 0.026 14.4 1.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Alpha_GJ PF03229.13 OAJ16064.1 - 1.2 9.7 6.9 1.5 9.4 0.2 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Rhodanese PF00581.20 OAJ16065.1 - 1.5e-05 25.5 0.0 2.9e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain DDE_Tnp_4 PF13359.6 OAJ16066.1 - 9.3e-07 28.6 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease VitK2_biosynth PF02621.14 OAJ16067.1 - 5.1e-61 206.5 0.0 5.9e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis NMT1_2 PF13379.6 OAJ16067.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 NMT1-like family Phosphonate-bd PF12974.7 OAJ16067.1 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein RRN3 PF05327.11 OAJ16068.1 - 3.8e-142 474.7 0.0 2.9e-105 352.9 0.0 3.6 2 2 1 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAJ16068.1 - 0.81 7.8 11.0 1.6 6.8 11.0 1.4 1 0 0 1 1 1 0 Nop14-like family PP1c_bdg PF10488.9 OAJ16068.1 - 1.9 7.9 11.8 4.4 6.7 11.8 1.5 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Maf PF02545.14 OAJ16069.1 - 2.5e-46 157.6 0.0 2.9e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein UDPGT PF00201.18 OAJ16070.1 - 2.6e-12 46.3 0.0 4.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GATA PF00320.27 OAJ16071.1 - 0.16 11.6 6.7 0.13 11.8 1.8 2.7 2 0 0 2 2 2 0 GATA zinc finger ERM PF00769.19 OAJ16071.1 - 1.3 8.8 23.5 0.024 14.4 16.4 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2570 PF10828.8 OAJ16071.1 - 1.3 8.9 4.8 3.2 7.6 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CENP-H PF05837.12 OAJ16071.1 - 3 8.3 9.5 6.8 7.1 9.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ABC_tran PF00005.27 OAJ16072.1 - 1e-47 162.1 0.0 2.6e-27 96.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ16072.1 - 3.9e-46 157.9 20.1 1.3e-24 87.4 12.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.6 OAJ16072.1 - 6.7e-14 52.9 2.2 2e-08 35.0 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 OAJ16072.1 - 2.1e-13 50.8 0.6 1.9e-05 24.6 0.1 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ16072.1 - 8.2e-11 41.8 7.6 1e-05 25.1 0.1 4.4 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ16072.1 - 2.9e-09 36.5 0.1 0.0026 17.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ16072.1 - 1e-07 32.5 3.1 0.016 15.6 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 OAJ16072.1 - 2e-07 31.1 1.2 8.4e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ16072.1 - 3.3e-07 30.4 0.1 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ16072.1 - 2.4e-06 27.6 0.3 0.0082 16.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 OAJ16072.1 - 2.5e-06 26.8 0.0 0.02 13.9 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ16072.1 - 2e-05 24.9 1.3 0.35 11.1 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 OAJ16072.1 - 7.5e-05 23.2 0.1 0.58 10.6 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAJ16072.1 - 0.00026 20.6 1.0 1.1 8.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain Adeno_IVa2 PF02456.15 OAJ16072.1 - 0.0005 19.0 0.0 0.79 8.4 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein DUF87 PF01935.17 OAJ16072.1 - 0.0006 20.0 1.1 0.0021 18.2 0.1 2.4 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 OAJ16072.1 - 0.00096 18.5 0.0 0.42 9.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 OAJ16072.1 - 0.0016 18.5 3.2 0.47 10.5 1.2 3.0 2 1 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 OAJ16072.1 - 0.0017 18.5 0.5 1.4 9.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 OAJ16072.1 - 0.0018 17.9 0.1 0.0057 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OAJ16072.1 - 0.0041 17.5 0.7 0.86 10.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase ABC_ATPase PF09818.9 OAJ16072.1 - 0.0042 15.9 3.6 0.92 8.2 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_28 PF13521.6 OAJ16072.1 - 0.0077 16.5 0.3 4.3 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAJ16072.1 - 0.0093 15.7 0.2 8.7 6.0 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein NACHT PF05729.12 OAJ16072.1 - 0.012 15.6 1.8 3 7.8 0.0 2.9 3 0 0 3 3 2 0 NACHT domain ATPase_2 PF01637.18 OAJ16072.1 - 0.014 15.3 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OAJ16072.1 - 0.015 14.8 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 OAJ16072.1 - 0.016 15.4 2.5 8 6.7 0.1 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 OAJ16072.1 - 0.016 15.0 0.0 15 5.2 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 OAJ16072.1 - 0.019 14.2 0.2 9.2 5.4 0.0 2.9 4 0 0 4 4 3 0 NB-ARC domain AAA_18 PF13238.6 OAJ16072.1 - 0.022 15.3 1.8 8.9 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ16072.1 - 0.028 13.8 0.1 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 OAJ16072.1 - 0.053 12.7 0.0 3.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAJ16072.1 - 0.058 13.1 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 OAJ16072.1 - 0.064 13.2 1.6 9.5 6.1 0.0 2.7 3 0 0 3 3 2 0 NTPase cobW PF02492.19 OAJ16072.1 - 0.088 12.4 1.7 7.3 6.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 OAJ16072.1 - 0.1 12.5 0.4 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 OAJ16072.1 - 0.18 11.8 0.0 5.9 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 OAJ16072.1 - 0.21 10.9 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Septin CFEM PF05730.11 OAJ16073.1 - 0.33 11.1 5.7 0.6 10.3 5.2 1.8 1 1 0 1 1 1 0 CFEM domain FAM199X PF15814.5 OAJ16073.1 - 2 7.4 8.6 2.4 7.1 8.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X Questin_oxidase PF14027.6 OAJ16074.1 - 1.4e-75 254.9 3.0 1.8e-75 254.6 3.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Metallophos PF00149.28 OAJ16075.1 - 2e-09 38.2 0.2 3.7e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HOOK PF05622.12 OAJ16076.1 - 0.0013 17.0 2.5 0.0013 17.0 2.5 1.9 2 0 0 2 2 2 1 HOOK protein TMF_DNA_bd PF12329.8 OAJ16076.1 - 0.0032 17.4 1.2 0.0032 17.4 1.2 3.0 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding CCDC144C PF14915.6 OAJ16076.1 - 0.036 13.2 0.3 0.036 13.2 0.3 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region APG6_N PF17675.1 OAJ16076.1 - 0.04 14.4 16.9 0.42 11.1 1.3 3.1 3 0 0 3 3 3 0 Apg6 coiled-coil region ATG16 PF08614.11 OAJ16076.1 - 0.052 13.8 20.7 0.05 13.8 10.9 2.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Latarcin PF10279.9 OAJ16076.1 - 0.078 13.4 7.2 0.61 10.5 0.1 2.8 2 1 0 2 2 2 0 Latarcin precursor DUF4483 PF14825.6 OAJ16076.1 - 0.12 12.1 0.2 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) AKNA PF12443.8 OAJ16076.1 - 0.19 12.4 3.4 0.43 11.3 0.5 3.1 3 0 0 3 3 3 0 AT-hook-containing transcription factor FH2 PF02181.23 OAJ16076.1 - 0.2 10.7 1.7 0.36 9.9 0.5 1.9 2 0 0 2 2 2 0 Formin Homology 2 Domain Rootletin PF15035.6 OAJ16076.1 - 0.5 10.4 14.5 0.83 9.6 2.4 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Cnn_1N PF07989.11 OAJ16076.1 - 0.72 10.1 4.3 5.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 OAJ16076.1 - 0.98 9.7 11.6 8.4 6.7 0.8 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 OAJ16076.1 - 1 9.6 15.1 1.6 9.0 0.4 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Sec2p PF06428.11 OAJ16076.1 - 1.1 9.3 8.7 1.7 8.7 0.1 2.9 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 OAJ16076.1 - 1.1 9.9 4.4 55 4.5 0.2 3.1 3 0 0 3 3 3 0 Initiation control protein YabA Leu_zip PF15294.6 OAJ16076.1 - 1.9 7.9 5.2 3.6 7.0 0.2 2.4 3 0 0 3 3 3 0 Leucine zipper DUF4763 PF15960.5 OAJ16076.1 - 2.3 7.4 10.0 1 8.6 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) GAS PF13851.6 OAJ16076.1 - 2.6 7.4 16.7 8.6 5.6 1.2 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tektin PF03148.14 OAJ16076.1 - 2.6 6.7 15.0 0.086 11.6 1.0 3.0 3 0 0 3 3 3 0 Tektin family Prefoldin_2 PF01920.20 OAJ16076.1 - 2.7 8.0 8.3 37 4.3 0.4 3.2 3 0 0 3 3 3 0 Prefoldin subunit HAUS-augmin3 PF14932.6 OAJ16076.1 - 2.8 7.5 9.5 2.8 7.5 0.2 3.0 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Ax_dynein_light PF10211.9 OAJ16076.1 - 3.9 7.4 11.3 1.2 9.1 1.6 3.0 3 0 0 3 3 3 0 Axonemal dynein light chain ZapB PF06005.12 OAJ16076.1 - 6.6 7.3 20.2 0.31 11.5 3.0 3.0 3 0 0 3 3 3 0 Cell division protein ZapB KLRAQ PF10205.9 OAJ16076.1 - 8 6.8 8.2 1.5 9.1 0.0 2.7 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 OAJ16076.1 - 9 5.1 16.7 3.9 6.3 0.3 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein LXG PF04740.12 OAJ16076.1 - 9.7 5.8 7.7 1.1 8.9 0.3 2.6 3 0 0 3 3 3 0 LXG domain of WXG superfamily Peptidase_M22 PF00814.25 OAJ16088.1 - 6.2e-66 222.9 0.2 8.6e-66 222.4 0.2 1.2 1 0 0 1 1 1 1 Glycoprotease family Amidinotransf PF02274.17 OAJ16089.1 - 1.8e-12 47.1 0.0 1.4e-10 40.8 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase PQ-loop PF04193.14 OAJ16090.1 - 4e-14 52.1 4.2 1.7e-12 46.9 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 OAJ16090.1 - 0.052 14.4 0.6 0.15 12.9 0.6 1.8 1 1 0 1 1 1 0 ER lumen protein retaining receptor Alpha_GJ PF03229.13 OAJ16090.1 - 0.65 10.6 5.3 1.7 9.2 0.9 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J ThrE PF06738.12 OAJ16090.1 - 0.82 9.0 4.3 0.15 11.4 0.7 1.6 2 0 0 2 2 2 0 Putative threonine/serine exporter zf-RING_5 PF14634.6 OAJ16091.1 - 0.0024 17.8 0.4 0.0044 16.9 0.0 1.6 2 0 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 OAJ16091.1 - 0.084 12.2 0.4 0.17 11.2 0.3 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_UBOX PF13445.6 OAJ16091.1 - 0.38 10.8 0.1 0.38 10.8 0.1 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ16091.1 - 0.42 11.0 0.1 0.42 11.0 0.1 1.7 2 0 0 2 2 2 0 Ring finger domain MRG PF05712.13 OAJ16092.1 - 1.7e-58 197.2 0.0 2.4e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAJ16092.1 - 1.7e-10 40.6 0.0 4.5e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain TFIIA PF03153.13 OAJ16093.1 - 0.92 9.4 13.9 36 4.2 13.9 2.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zds_C PF08632.10 OAJ16094.1 - 1e-26 92.4 1.1 2.1e-26 91.4 1.1 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CD24 PF14984.6 OAJ16094.1 - 0.11 12.8 0.1 0.11 12.8 0.1 4.4 4 0 0 4 4 4 0 CD24 protein Adaptin_N PF01602.20 OAJ16095.1 - 8.4e-104 348.0 0.0 1.1e-103 347.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAJ16095.1 - 4.5e-51 173.0 0.0 8.1e-51 172.1 0.0 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAJ16095.1 - 2.1e-30 105.2 0.0 6.1e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAJ16095.1 - 2.2e-19 69.6 0.9 7.7e-10 39.0 0.0 5.2 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 OAJ16095.1 - 3.7e-06 27.1 3.5 0.37 10.8 0.1 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ16095.1 - 0.00021 21.2 1.7 4.7 7.7 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 OAJ16095.1 - 0.45 11.3 6.9 27 5.8 0.1 5.2 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat WD40 PF00400.32 OAJ16096.1 - 7e-25 86.8 15.4 3.5e-05 24.5 0.0 7.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16096.1 - 4.1e-09 36.6 3.2 0.0085 16.4 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ16096.1 - 0.00053 19.0 0.1 2.6 6.9 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein MMtag PF10159.9 OAJ16098.1 - 1.1e-30 105.7 2.7 1.1e-30 105.7 2.7 3.1 2 1 1 3 3 3 1 Multiple myeloma tumor-associated DUF874 PF05917.11 OAJ16098.1 - 0.18 10.8 8.3 0.3 10.1 8.3 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) APG6_N PF17675.1 OAJ16098.1 - 0.3 11.6 17.8 2.8 8.5 12.3 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4042 PF13251.6 OAJ16099.1 - 7.7e-10 38.8 1.2 7.7e-10 38.8 1.2 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OAJ16099.1 - 4.7e-06 26.9 18.6 0.0056 17.0 0.6 5.8 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 OAJ16099.1 - 0.014 15.6 24.4 1.4 9.4 0.2 8.4 8 0 0 8 8 8 0 HEAT repeat SAM_DrpA PF18255.1 OAJ16099.1 - 0.21 11.9 0.0 0.84 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA processing protein A sterile alpha motif domain Cyto_heme_lyase PF01265.17 OAJ16100.1 - 1.1e-69 235.2 27.3 4.9e-55 187.2 11.8 3.6 1 1 2 3 3 3 2 Cytochrome c/c1 heme lyase DUF1640 PF07798.11 OAJ16101.1 - 2.8e-60 203.3 3.2 3.6e-60 203.0 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ParBc_2 PF08857.11 OAJ16101.1 - 0.094 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative ParB-like nuclease HALZ PF02183.18 OAJ16101.1 - 0.13 12.5 2.9 0.6 10.4 2.9 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper DotU PF09850.9 OAJ16101.1 - 0.17 11.5 1.6 2.2 8.0 0.0 2.7 2 2 0 2 2 2 0 Type VI secretion system protein DotU ADIP PF11559.8 OAJ16101.1 - 0.23 11.6 3.8 1.1 9.3 3.7 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 OAJ16101.1 - 0.86 9.9 4.2 6.7 7.0 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) Glyco_hydro_16 PF00722.21 OAJ16102.1 - 4.7e-05 22.9 0.0 8.7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Nucleopor_Nup85 PF07575.13 OAJ16104.1 - 2.3e-75 254.3 0.0 5.8e-42 144.0 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin Katanin_con80 PF13925.6 OAJ16104.1 - 0.066 13.3 0.1 12 5.9 0.1 2.5 2 0 0 2 2 2 0 con80 domain of Katanin PGA2 PF07543.12 OAJ16104.1 - 2.1 8.3 11.2 9.7 6.2 0.4 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 dCMP_cyt_deam_1 PF00383.23 OAJ16113.1 - 1.8e-25 88.8 1.9 2e-25 88.6 0.7 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ16113.1 - 1.6e-09 37.7 0.0 2.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 OAJ16113.1 - 0.0023 18.5 0.0 0.0058 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain APOBEC4_like PF18774.1 OAJ16113.1 - 0.055 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase SNAD4 PF18750.1 OAJ16113.1 - 0.057 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DNA_ligase_A_M PF01068.21 OAJ16114.1 - 1e-17 64.4 0.1 7.3e-07 29.0 0.0 3.7 2 2 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ16114.1 - 7.7e-07 29.6 0.1 1.1e-05 25.9 0.0 2.8 3 0 0 3 3 3 1 DNA ligase N terminus HGTP_anticodon PF03129.20 OAJ16116.1 - 7.2e-21 74.2 0.0 2.2e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ16116.1 - 6.7e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) BrnA_antitoxin PF14384.6 OAJ16116.1 - 0.017 15.6 0.5 0.057 13.9 0.5 1.9 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Chromo PF00385.24 OAJ16117.1 - 2.3e-15 56.2 3.5 4.4e-15 55.3 3.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OAJ16117.1 - 6.2e-13 48.6 0.0 3e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain DTHCT PF08070.11 OAJ16117.1 - 1.1 10.0 33.2 0.83 10.4 10.9 3.6 3 0 0 3 3 3 0 DTHCT (NUC029) region zf-C2H2 PF00096.26 OAJ16118.1 - 2.5e-20 71.7 21.9 0.00011 22.5 2.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ16118.1 - 2.6e-18 65.5 14.0 0.00017 21.9 0.7 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ16118.1 - 2.9e-11 43.2 20.2 0.0054 17.5 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ16118.1 - 0.00024 21.7 8.1 0.59 10.8 0.1 4.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-TRAF PF02176.18 OAJ16118.1 - 0.025 15.2 4.5 0.053 14.2 0.7 2.5 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 OAJ16118.1 - 0.033 14.5 7.3 4.6 7.7 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 OAJ16118.1 - 0.15 12.2 1.1 11 6.1 0.4 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 OAJ16118.1 - 0.16 12.0 13.0 0.66 10.0 0.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 OAJ16118.1 - 0.27 11.7 10.1 6.1 7.4 0.4 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Astro_capsid_p PF12226.8 OAJ16118.1 - 7.4 5.6 7.2 15 4.6 7.2 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PCMT PF01135.19 OAJ16119.1 - 3.4e-63 213.2 0.0 3e-62 210.1 0.0 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAJ16119.1 - 0.091 12.6 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16119.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PIG-H PF10181.9 OAJ16121.1 - 1e-06 28.5 0.1 2.8e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Mito_carr PF00153.27 OAJ16122.1 - 5.1e-49 164.1 4.8 1.7e-18 66.3 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ16122.1 - 0.0055 15.9 5.2 0.57 9.3 0.1 3.2 2 1 0 3 3 3 2 Gammaproteobacterial serine protease SpoVAB PF13782.6 OAJ16122.1 - 0.057 13.7 0.1 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Stage V sporulation protein AB PfkB PF00294.24 OAJ16124.1 - 4.7e-05 22.8 0.1 0.00094 18.6 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase TPMT PF05724.11 OAJ16125.1 - 2.3e-33 115.7 0.1 2.9e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAJ16125.1 - 1.2e-10 42.0 0.0 1.7e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16125.1 - 3.3e-09 36.7 0.0 6.1e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16125.1 - 3.3e-09 37.3 0.0 5.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16125.1 - 2.8e-06 28.0 0.0 4.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16125.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ16125.1 - 0.052 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OAJ16125.1 - 0.078 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OAJ16125.1 - 0.093 12.1 0.1 0.26 10.7 0.0 1.7 1 1 1 2 2 2 0 Tellurite resistance protein TehB Rep_fac_C PF08542.11 OAJ16126.1 - 9.5e-18 64.4 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAJ16126.1 - 2.3e-17 63.7 0.0 7.9e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ16126.1 - 2.9e-15 56.4 0.0 3.1e-11 43.3 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OAJ16126.1 - 1.8e-09 37.8 0.0 4.3e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 OAJ16126.1 - 9.7e-06 25.5 0.2 0.00057 19.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ16126.1 - 2.7e-05 24.0 0.1 8.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ16126.1 - 3.2e-05 24.0 0.0 0.0002 21.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAJ16126.1 - 3.3e-05 23.2 0.0 4.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 OAJ16126.1 - 5.7e-05 22.9 0.0 0.00027 20.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ16126.1 - 7.1e-05 23.2 0.0 0.00016 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 OAJ16126.1 - 0.00018 21.8 0.1 0.00056 20.2 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 OAJ16126.1 - 0.00022 21.5 0.2 0.084 13.2 0.2 3.1 2 2 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAJ16126.1 - 0.00038 20.3 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ16126.1 - 0.00044 20.3 0.0 0.0017 18.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OAJ16126.1 - 0.00048 19.9 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OAJ16126.1 - 0.00051 19.9 0.0 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_7 PF12775.7 OAJ16126.1 - 0.002 17.6 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 OAJ16126.1 - 0.0055 16.1 0.1 0.12 11.8 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein ResIII PF04851.15 OAJ16126.1 - 0.0068 16.4 0.0 0.22 11.5 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAJ16126.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 OAJ16126.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAJ16126.1 - 0.026 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 OAJ16126.1 - 0.029 14.1 0.1 0.32 10.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 OAJ16126.1 - 0.049 13.4 0.0 0.16 11.7 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 OAJ16126.1 - 0.058 13.9 0.0 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 OAJ16126.1 - 0.079 12.5 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAJ16126.1 - 0.13 11.6 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 OAJ16126.1 - 0.15 11.0 0.1 2.9 6.7 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_28 PF13521.6 OAJ16126.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Enkurin PF13864.6 OAJ16127.1 - 0.21 12.1 0.3 0.36 11.3 0.3 1.3 1 0 0 1 1 1 0 Calmodulin-binding DIM PF08194.12 OAJ16128.1 - 0.61 10.3 2.3 1.3 9.3 2.3 1.6 1 0 0 1 1 1 0 DIM protein F-box PF00646.33 OAJ16131.1 - 0.00016 21.5 0.2 0.00027 20.7 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ16131.1 - 0.0005 19.9 0.2 0.0013 18.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 OAJ16131.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain TRAM_LAG1_CLN8 PF03798.16 OAJ16132.1 - 2.2e-35 122.2 24.1 2.2e-35 122.2 24.1 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAJ16132.1 - 1e-18 66.7 0.1 3e-18 65.2 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein adh_short_C2 PF13561.6 OAJ16147.1 - 4.7e-58 196.5 0.1 4.7e-58 196.5 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ16147.1 - 6e-43 146.6 0.2 9.6e-43 145.9 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ16147.1 - 4.2e-13 49.6 0.1 4.2e-13 49.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 OAJ16147.1 - 0.00016 21.2 0.1 0.00039 20.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAJ16147.1 - 0.03 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 OAJ16148.1 - 3e-13 50.2 0.0 6.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Stealth_CR2 PF11380.8 OAJ16149.1 - 2.2e-14 53.6 0.0 2.5e-09 37.3 0.0 3.9 4 0 0 4 4 4 2 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 OAJ16149.1 - 1.5e-06 28.0 0.1 9.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 OAJ16149.1 - 3.3e-05 23.7 0.2 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OAJ16149.1 - 0.0021 17.7 0.1 0.0045 16.7 0.1 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 RRM_1 PF00076.22 OAJ16150.1 - 1.4e-18 66.5 0.0 2.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ16150.1 - 0.0094 15.5 0.0 2.5 7.7 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1687 PF07955.11 OAJ16151.1 - 2.2e-11 44.3 1.8 9.8e-09 35.8 0.1 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1687) LON_substr_bdg PF02190.16 OAJ16151.1 - 0.067 13.0 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain DEC-1_N PF04625.13 OAJ16151.1 - 2.2 7.2 6.2 2.7 6.9 6.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NIF3 PF01784.18 OAJ16152.1 - 3.2e-56 190.7 0.0 4e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Pkinase PF00069.25 OAJ16153.1 - 2e-31 109.3 0.0 3.2e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16153.1 - 8.8e-16 58.0 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ16153.1 - 8e-05 22.7 0.1 0.00047 20.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ16153.1 - 0.0047 16.3 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ16153.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAJ16153.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ras PF00071.22 OAJ16154.1 - 3.4e-58 195.8 0.0 4e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ16154.1 - 3.1e-35 121.0 0.0 4.1e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ16154.1 - 2.8e-12 46.4 0.0 3.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ16154.1 - 2.8e-05 24.2 0.0 3.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ16154.1 - 0.00011 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ16154.1 - 0.00022 20.8 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ16154.1 - 0.00045 20.2 0.2 0.4 10.6 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 OAJ16154.1 - 0.013 15.9 0.2 0.024 15.0 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain Mon2_C PF16206.5 OAJ16156.1 - 0.24 9.5 0.0 0.36 8.9 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein Pribosyl_synth PF14572.6 OAJ16157.1 - 0.019 15.0 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Pkinase PF00069.25 OAJ16159.1 - 2.1e-09 37.1 0.0 5.8e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16159.1 - 0.0074 15.6 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ16160.1 - 9.8e-10 38.2 0.0 2.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16160.1 - 9.7e-06 25.0 0.0 7.5e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase CUE PF02845.16 OAJ16161.1 - 0.028 14.1 0.1 17 5.3 0.0 3.8 3 1 1 4 4 4 0 CUE domain PBP1_TM PF14812.6 OAJ16161.1 - 0.061 13.7 4.5 7.3 7.0 1.7 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OAJ16161.1 - 7.1 6.3 8.4 3.2 7.4 0.5 3.1 3 0 0 3 3 3 0 FAM176 family Nodulin PF02451.15 OAJ16162.1 - 0.0055 16.2 1.6 0.013 15.0 0.5 2.2 2 0 0 2 2 2 1 Nodulin TPR_12 PF13424.6 OAJ16163.1 - 4.8e-10 39.6 23.9 0.019 15.3 0.4 7.8 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16163.1 - 1e-09 37.8 16.1 0.026 14.6 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ16163.1 - 2e-07 30.7 7.5 4.3 7.8 0.1 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ16163.1 - 3.1e-06 26.7 9.6 0.49 10.3 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ16163.1 - 6e-05 23.5 15.3 0.12 12.9 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ16163.1 - 6.7e-05 23.4 19.0 6.4 7.9 0.0 7.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ16163.1 - 0.00044 20.1 15.3 4.9 7.4 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ16163.1 - 0.00067 19.4 23.0 0.3 11.0 0.3 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat PPR PF01535.20 OAJ16163.1 - 0.068 13.4 2.6 5.7 7.4 0.0 4.1 5 0 0 5 5 5 0 PPR repeat Zn_clus PF00172.18 OAJ16177.1 - 3.7e-05 23.7 8.3 6.6e-05 23.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.9 OAJ16177.1 - 3.3 6.1 6.6 5.9 5.3 6.6 1.3 1 0 0 1 1 1 0 Macoilin family VIR_N PF15912.5 OAJ16177.1 - 3.8 7.0 7.5 7.3 6.1 7.5 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal TFIIA PF03153.13 OAJ16177.1 - 5.9 6.8 13.3 6.4 6.7 10.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit KCH PF16944.5 OAJ16178.1 - 1.8e-81 273.6 17.0 2.4e-81 273.2 17.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel PITH PF06201.13 OAJ16180.1 - 4e-30 105.0 0.0 6.7e-28 97.8 0.0 2.2 1 1 0 1 1 1 1 PITH domain Drf_GBD PF06371.13 OAJ16182.1 - 9.2e-13 48.2 0.1 3.3e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Rcd1 PF04078.13 OAJ16182.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like DUF4471 PF14740.6 OAJ16182.1 - 0.19 10.9 0.1 0.27 10.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) TFIIA PF03153.13 OAJ16182.1 - 0.67 9.9 10.1 0.91 9.5 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 OAJ16183.1 - 3.5e-11 43.7 0.0 1.7e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3978 PF13123.6 OAJ16183.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) Mito_carr PF00153.27 OAJ16185.1 - 0.063 13.2 0.3 4.1 7.4 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial carrier protein ATP-synt_DE_N PF02823.16 OAJ16186.1 - 5.9e-17 61.3 0.0 8.5e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DBR1 PF05011.13 OAJ16187.1 - 3e-23 82.8 0.0 4.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain DnaJ_C PF01556.18 OAJ16189.1 - 4e-41 140.5 0.4 5.3e-41 140.2 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ16189.1 - 1e-20 73.6 0.3 1.8e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ16189.1 - 5.5e-16 58.7 20.9 8.9e-16 58.0 20.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAJ16189.1 - 1.1e-05 25.3 9.1 0.0039 17.1 0.7 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAJ16189.1 - 0.14 12.2 12.4 1.1 9.3 1.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 OAJ16189.1 - 0.21 11.2 7.9 3.3 7.3 2.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 PS_Dcarbxylase PF02666.15 OAJ16190.1 - 2.9e-73 245.7 0.0 9.5e-55 185.3 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 OAJ16190.1 - 0.00024 20.7 0.0 0.00055 19.6 0.0 1.5 1 0 0 1 1 1 1 MNLL subunit AA_permease PF00324.21 OAJ16191.1 - 5.9e-141 470.3 45.1 7.1e-141 470.1 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ16191.1 - 1.3e-39 136.3 47.7 1.6e-39 136.0 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3093 PF11292.8 OAJ16191.1 - 8.9 6.6 9.1 0.89 9.8 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3093) HMG_box PF00505.19 OAJ16192.1 - 4.7e-10 39.7 2.8 5.4e-07 29.9 1.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ16192.1 - 0.085 13.5 2.2 0.23 12.1 2.2 1.8 1 1 0 1 1 1 0 HMG-box domain RAI1 PF08652.11 OAJ16204.1 - 2.6e-19 69.2 0.0 5.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Asp PF00026.23 OAJ16205.1 - 5.8e-57 193.5 0.0 8.4e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease adh_short PF00106.25 OAJ16205.1 - 1.3e-42 145.5 0.1 2.1e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ16205.1 - 2.8e-28 99.1 0.0 5.7e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ16205.1 - 1.9e-12 47.5 0.4 1.8e-11 44.3 0.4 2.3 1 1 0 1 1 1 1 KR domain TAXi_N PF14543.6 OAJ16205.1 - 1.5e-10 41.6 0.5 6.5e-08 33.0 0.5 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Epimerase PF01370.21 OAJ16205.1 - 2.5e-05 23.8 0.0 0.00029 20.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Asp_protease_2 PF13650.6 OAJ16205.1 - 0.0028 18.2 0.6 0.54 10.9 0.0 3.5 2 1 1 3 3 3 1 Aspartyl protease 3Beta_HSD PF01073.19 OAJ16205.1 - 0.0057 15.7 0.1 0.0084 15.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family gag-asp_proteas PF13975.6 OAJ16205.1 - 0.019 15.5 0.2 0.93 10.1 0.0 2.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease GDP_Man_Dehyd PF16363.5 OAJ16205.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAJ16205.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding TPR_1 PF00515.28 OAJ16206.1 - 1.3e-10 40.6 4.1 6.6e-07 28.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16206.1 - 1.6e-06 27.8 6.1 0.00083 19.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ16206.1 - 5.8e-05 23.2 0.8 0.09 13.2 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ16206.1 - 0.00028 20.5 0.7 0.23 11.1 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 OAJ16206.1 - 0.0012 19.4 0.9 1.3 10.0 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ16206.1 - 0.012 15.8 4.2 0.065 13.5 0.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ16206.1 - 0.012 15.9 2.1 0.24 11.7 0.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ16206.1 - 0.025 15.2 0.5 0.05 14.2 0.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CvfB_WH PF17783.1 OAJ16206.1 - 0.13 12.0 0.2 2.8 7.8 0.1 2.2 2 0 0 2 2 2 0 CvfB-like winged helix domain DLH PF01738.18 OAJ16207.1 - 1.3e-12 47.8 0.3 1.5e-12 47.5 0.3 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Adeno_E3_CR2 PF02439.15 OAJ16208.1 - 0.022 14.5 0.5 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PMP1_2 PF08114.11 OAJ16208.1 - 0.038 13.7 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Mucin PF01456.17 OAJ16208.1 - 0.074 13.1 36.9 0.19 11.7 36.9 1.9 1 0 0 1 1 1 0 Mucin-like glycoprotein Podoplanin PF05808.11 OAJ16208.1 - 0.13 12.3 18.7 0.61 10.2 18.7 2.0 1 1 0 1 1 1 0 Podoplanin Glycophorin_A PF01102.18 OAJ16208.1 - 2.6 8.3 0.0 2.6 8.3 0.0 2.8 3 0 0 3 3 3 0 Glycophorin A Dynamin_M PF01031.20 OAJ16209.1 - 7.2e-109 363.4 0.0 1.9e-108 362.0 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ16209.1 - 2.4e-55 187.1 0.0 5.2e-55 186.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAJ16209.1 - 3.1e-29 101.0 0.3 2.1e-28 98.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAJ16209.1 - 0.00068 19.7 0.5 0.0077 16.3 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase TipAS PF07739.13 OAJ16209.1 - 0.089 13.3 0.1 0.52 10.9 0.0 2.3 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Plus-3 PF03126.18 OAJ16210.1 - 7.8e-12 45.7 0.0 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain NAD_binding_6 PF08030.12 OAJ16210.1 - 0.2 11.8 0.8 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain CLASP_N PF12348.8 OAJ16211.1 - 2.1e-18 66.7 0.0 3.8e-05 23.4 0.0 5.2 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 OAJ16211.1 - 6.2e-13 47.8 20.7 0.00092 19.3 0.1 10.6 12 0 0 12 12 12 3 HEAT repeat Cnd1 PF12717.7 OAJ16211.1 - 5.3e-10 39.6 7.4 0.025 14.6 0.0 7.3 8 0 0 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ16211.1 - 7.6e-10 39.1 6.9 0.078 13.4 0.0 8.2 7 2 2 9 9 9 3 HEAT repeats TAN PF11640.8 OAJ16211.1 - 8.8e-06 25.9 0.1 1.4 9.0 0.1 4.9 4 0 0 4 4 4 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 OAJ16211.1 - 4.9e-05 23.7 6.4 3.5 8.2 0.0 7.0 6 0 0 6 6 6 2 HEAT-like repeat Cohesin_HEAT PF12765.7 OAJ16211.1 - 0.001 19.3 0.3 2.1 8.7 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion Proteasom_PSMB PF10508.9 OAJ16211.1 - 0.0017 17.0 0.0 5.4 5.4 0.0 3.6 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.7 OAJ16211.1 - 0.013 16.1 0.0 52 4.5 0.0 5.2 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region DCB PF16213.5 OAJ16211.1 - 1.7 8.3 5.7 2.9 7.5 0.0 4.0 5 1 1 6 6 6 0 Dimerisation and cyclophilin-binding domain of Mon2 Cpn60_TCP1 PF00118.24 OAJ16212.1 - 3.5e-159 530.6 2.9 1.1e-157 525.6 2.9 2.0 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GTP_EFTU PF00009.27 OAJ16214.1 - 9.6e-65 217.8 0.4 1.4e-64 217.2 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ16214.1 - 2.3e-32 111.3 0.0 5.7e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ16214.1 - 1.1e-21 76.7 0.0 2.4e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ16214.1 - 3.6e-13 49.4 0.0 9.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ16214.1 - 1.8e-12 47.5 0.0 5.6e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ16214.1 - 0.00093 19.3 0.1 0.002 18.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ada_Zn_binding PF02805.16 OAJ16215.1 - 3.4e-20 71.8 8.6 7e-20 70.8 8.6 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAJ16215.1 - 0.0083 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family ADIP PF11559.8 OAJ16216.1 - 2.8e-21 76.2 4.5 2.8e-21 76.2 4.5 2.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding MatP_C PF17414.2 OAJ16216.1 - 0.23 11.7 1.7 2.3 8.5 0.4 2.8 1 1 1 2 2 2 0 MatP C-terminal ribbon-helix-helix domain TMCO5 PF14992.6 OAJ16216.1 - 0.5 9.9 4.2 1.1 8.8 1.0 2.2 2 0 0 2 2 2 0 TMCO5 family Noelin-1 PF12308.8 OAJ16216.1 - 1.1 9.3 3.8 1.8 8.6 0.2 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein HAUS-augmin3 PF14932.6 OAJ16216.1 - 2.2 7.8 7.4 3 7.3 3.7 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 OAJ16216.1 - 2.3 7.0 11.4 3.4 6.4 6.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2570 PF10828.8 OAJ16216.1 - 5 7.0 8.2 1.6 8.6 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) TSC22 PF01166.18 OAJ16216.1 - 5.9 7.3 7.8 1.5 9.2 0.5 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF1664 PF07889.12 OAJ16216.1 - 6 6.9 7.5 3.5 7.7 2.5 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAJ16216.1 - 6.8 7.2 18.2 4.3 7.9 7.3 3.1 3 1 0 3 3 3 0 Apg6 coiled-coil region Clathrin PF00637.20 OAJ16229.1 - 5.6e-15 55.5 0.1 3e-06 27.2 0.0 3.4 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.8 OAJ16229.1 - 5.4e-11 42.5 0.5 1.3e-10 41.3 0.5 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAJ16229.1 - 7.4e-10 38.7 7.8 1.7e-09 37.5 7.8 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 OAJ16229.1 - 0.0046 16.8 7.0 0.0079 16.0 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ16229.1 - 0.036 14.4 6.3 0.064 13.6 6.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAJ16229.1 - 0.14 12.1 6.4 0.25 11.3 6.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ16229.1 - 1.3 9.1 5.5 2.8 8.0 5.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OAJ16229.1 - 8 6.8 6.5 15 6.0 6.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain ALG3 PF05208.13 OAJ16230.1 - 1.2e-131 439.5 9.5 1.4e-131 439.2 9.5 1.1 1 0 0 1 1 1 1 ALG3 protein PBP PF01161.20 OAJ16231.1 - 6.8e-09 36.1 0.0 1.4e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Nop25 PF09805.9 OAJ16232.1 - 1.9e-16 60.7 20.8 1.9e-16 60.7 20.8 3.6 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) GRP PF07172.11 OAJ16232.1 - 0.0071 17.0 14.2 0.0071 17.0 14.2 2.2 2 0 0 2 2 2 1 Glycine rich protein family MAT1 PF06391.13 OAJ16233.1 - 5.8e-44 150.4 8.1 7.7e-44 150.0 8.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAJ16233.1 - 4.5e-17 61.7 7.6 7.1e-17 61.0 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ16233.1 - 0.0001 22.1 7.9 0.00049 19.9 3.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ16233.1 - 0.00013 21.7 8.3 0.00069 19.4 8.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ16233.1 - 0.00062 20.1 6.0 0.0012 19.2 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ16233.1 - 0.00088 19.1 11.0 0.0075 16.1 11.8 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ16233.1 - 0.0028 17.6 9.4 0.01 15.8 9.7 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAJ16233.1 - 0.0069 16.1 7.7 0.059 13.2 3.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 OAJ16233.1 - 0.085 13.0 5.0 1.4 9.1 1.6 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 OAJ16233.1 - 0.23 11.5 7.4 0.44 10.6 7.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 OAJ16233.1 - 0.79 9.4 6.0 1 9.1 5.3 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAJ16233.1 - 1.7 8.5 12.5 9.8 6.1 12.8 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Zn-ribbon_8 PF09723.10 OAJ16233.1 - 6.7 6.9 9.4 57 3.9 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_UBOX PF13445.6 OAJ16233.1 - 10 6.3 8.8 19 5.4 8.8 1.4 1 0 0 1 1 1 0 RING-type zinc-finger NAD_binding_2 PF03446.15 OAJ16235.1 - 9.2e-23 81.1 0.1 1.4e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ16235.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAJ16235.1 - 6.2e-06 26.3 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAJ16235.1 - 1.5e-05 25.5 0.2 0.0024 18.4 0.0 3.0 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent UvrC_HhH_N PF08459.11 OAJ16235.1 - 0.029 14.3 0.0 0.029 14.3 0.0 1.3 1 1 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal NAD_binding_10 PF13460.6 OAJ16235.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 OAJ16235.1 - 0.13 12.2 0.9 1.2 8.9 0.9 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.18 OAJ16236.1 - 0.03 14.4 6.8 0.083 13.0 6.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 OAJ16237.1 - 1.5e-48 165.2 8.3 2.1e-48 164.7 8.3 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3449 PF11931.8 OAJ16238.1 - 5.3e-72 241.5 0.7 2.1e-71 239.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAJ16238.1 - 1.4e-23 83.2 0.2 4.8e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 OAJ16238.1 - 0.00035 20.9 4.6 0.0072 16.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAJ16238.1 - 0.003 17.8 8.3 0.0038 17.5 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAJ16238.1 - 0.005 17.2 0.7 3.9 7.9 0.2 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SF3a60_bindingd PF12108.8 OAJ16238.1 - 0.015 15.2 0.2 0.036 14.0 0.2 1.6 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain zf-DBF PF07535.12 OAJ16238.1 - 0.051 13.7 3.7 2.7 8.2 0.1 2.7 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 OAJ16238.1 - 0.71 10.9 3.3 41 5.4 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.9 OAJ16238.1 - 5.5 7.3 5.9 6.3 7.2 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Methyltransf_23 PF13489.6 OAJ16239.1 - 1.5e-10 41.1 0.0 3.1e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ16239.1 - 4.1e-08 33.8 0.0 1.1e-07 32.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16239.1 - 1.3e-06 29.0 0.0 6.2e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16239.1 - 2.5e-06 28.1 0.0 4.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16239.1 - 0.00027 20.7 0.0 0.00071 19.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ16239.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 OAJ16239.1 - 0.087 12.4 1.3 0.43 10.1 0.1 2.2 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW MTS PF05175.14 OAJ16239.1 - 0.14 11.7 0.0 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Acetate_kinase PF00871.17 OAJ16240.1 - 6.1e-60 203.0 0.0 7.9e-43 146.6 0.0 3.1 3 0 0 3 3 3 3 Acetokinase family Arrestin_C PF02752.22 OAJ16241.1 - 0.011 16.2 0.0 0.39 11.2 0.0 2.7 2 1 1 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Spem1 PF15670.5 OAJ16241.1 - 0.065 12.8 0.8 0.11 12.0 0.8 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 JmjC PF02373.22 OAJ16242.1 - 3.2e-12 46.9 0.0 1.1e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAJ16242.1 - 2.4e-08 34.0 0.0 8.9e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Cupin-like domain F-box-like PF12937.7 OAJ16242.1 - 0.0082 16.0 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 OAJ16242.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein 2-oxoacid_dh PF00198.23 OAJ16243.1 - 1.4e-55 188.3 0.0 2.1e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ16243.1 - 1.8e-19 69.3 0.2 4.2e-19 68.2 0.2 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ16243.1 - 7.8e-14 51.7 0.2 2e-13 50.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ16243.1 - 0.11 12.3 0.1 0.45 10.4 0.1 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like PYNP_C PF07831.13 OAJ16243.1 - 0.12 12.1 0.0 14 5.4 0.0 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.7 OAJ16243.1 - 0.19 10.4 0.0 0.37 9.5 0.0 1.4 1 1 0 1 1 1 0 HlyD family secretion protein Glycos_transf_3 PF00591.21 OAJ16244.1 - 4.9e-66 222.9 0.0 2.1e-62 211.0 0.0 2.3 1 1 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAJ16244.1 - 0.0018 18.1 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF1682 PF07946.14 OAJ16244.1 - 0.035 13.3 5.5 0.051 12.8 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4228 PF14009.6 OAJ16244.1 - 0.041 14.3 3.6 0.08 13.3 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) SASP PF00269.20 OAJ16244.1 - 0.14 12.2 1.5 0.29 11.2 1.5 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type HIT PF01230.23 OAJ16245.1 - 5e-25 88.1 0.0 6.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ16245.1 - 7.7e-07 29.6 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding UPF0370 PF13980.6 OAJ16246.1 - 1 9.5 3.3 0.63 10.1 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) SK_channel PF03530.14 OAJ16246.1 - 2.7 8.0 6.3 3 7.9 0.9 2.4 1 1 1 2 2 2 0 Calcium-activated SK potassium channel Cnd2 PF05786.14 OAJ16247.1 - 0.014 14.1 0.1 0.014 14.1 0.1 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 CENP-B_dimeris PF09026.10 OAJ16247.1 - 0.057 13.8 7.6 0.094 13.1 7.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 OAJ16247.1 - 0.1 12.2 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 OAJ16247.1 - 6.1 6.1 10.4 8.6 5.6 10.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 OAJ16247.1 - 6.3 5.8 10.7 8.3 5.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CTP_synth_N PF06418.14 OAJ16248.1 - 1.1e-119 398.7 0.0 1.4e-119 398.3 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAJ16248.1 - 2.4e-48 164.4 0.0 7.1e-38 130.3 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 OAJ16248.1 - 0.085 12.9 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Drc1-Sld2 PF11719.8 OAJ16250.1 - 2.5e-06 27.3 34.1 2.5e-06 27.3 34.1 2.9 1 1 1 2 2 2 1 DNA replication and checkpoint protein FAD_binding_3 PF01494.19 OAJ16251.1 - 3.1e-22 79.3 0.3 5.6e-12 45.6 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ16251.1 - 6e-08 32.7 0.1 5.3e-07 29.5 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 OAJ16251.1 - 2.3e-05 23.6 0.0 0.096 11.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 OAJ16251.1 - 2.7e-05 24.3 0.0 7.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ16251.1 - 8.3e-05 23.1 0.0 0.0045 17.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ16251.1 - 0.00052 19.2 0.1 0.001 18.3 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAJ16251.1 - 0.00061 19.1 0.1 0.0082 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ16251.1 - 0.00065 18.5 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 OAJ16251.1 - 0.00083 19.0 0.0 0.00083 19.0 0.0 2.1 2 0 0 2 2 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ16251.1 - 0.0025 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OAJ16251.1 - 0.0069 15.3 0.0 0.77 8.5 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OAJ16251.1 - 0.01 14.9 0.6 0.019 14.0 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 OAJ16251.1 - 0.027 13.8 0.2 0.048 13.0 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAJ16251.1 - 0.034 13.5 0.1 0.29 10.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAJ16251.1 - 0.079 12.5 0.4 0.37 10.4 0.2 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAJ16251.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 OAJ16251.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 OAJ16251.1 - 0.25 10.7 1.6 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 ThiF family NIF PF03031.18 OAJ16263.1 - 6.6e-54 181.9 0.1 9.1e-54 181.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sigma70_ner PF04546.13 OAJ16263.1 - 0.035 14.0 2.3 0.079 12.8 2.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region HAD PF12710.7 OAJ16263.1 - 0.094 13.1 0.1 0.6 10.5 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Thiolase_N PF00108.23 OAJ16264.1 - 6.4e-66 222.4 0.2 1.4e-65 221.3 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ16264.1 - 3.9e-44 149.2 0.1 9.3e-44 148.0 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ16264.1 - 8.7e-06 25.5 1.9 3.9e-05 23.4 0.2 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ16264.1 - 0.035 14.0 0.2 5 7.1 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 OAJ16264.1 - 0.059 13.5 0.1 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HTH_8 PF02954.19 OAJ16264.1 - 0.06 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Abhydrolase_2 PF02230.16 OAJ16265.1 - 6.3e-58 196.1 0.0 8.4e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAJ16265.1 - 5e-07 30.5 0.0 5.7e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ16265.1 - 2.1e-06 27.2 0.1 0.0089 15.3 0.0 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ16265.1 - 0.00013 21.8 0.0 0.00047 19.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAJ16265.1 - 0.0034 16.9 0.0 0.013 15.0 0.0 2.0 1 1 1 2 2 2 1 Esterase PHB depolymerase Cutinase PF01083.22 OAJ16265.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.21 OAJ16265.1 - 0.059 12.8 0.0 0.62 9.5 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 OAJ16265.1 - 0.077 12.6 0.0 0.4 10.3 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 OAJ16265.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) zf-HIT PF04438.16 OAJ16268.1 - 9.8e-08 31.7 9.7 1.5e-07 31.1 9.7 1.2 1 0 0 1 1 1 1 HIT zinc finger LANC_like PF05147.13 OAJ16269.1 - 0.26 9.8 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Trypan_PARP PF05887.11 OAJ16269.1 - 3.1 7.8 8.9 1.7 8.7 6.8 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BCIP PF13862.6 OAJ16270.1 - 5.6e-34 117.7 0.0 1e-33 116.9 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF4129 PF13559.6 OAJ16270.1 - 0.049 13.9 0.3 19 5.6 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) TLP-20 PF06088.11 OAJ16270.1 - 0.072 13.0 1.8 6.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ORC6 PF05460.13 OAJ16270.1 - 0.099 11.9 3.7 0.44 9.8 0.8 2.1 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TFIIF_alpha PF05793.12 OAJ16270.1 - 1.4 7.4 11.2 1.1 7.8 0.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spt5_N PF11942.8 OAJ16270.1 - 1.7 9.6 9.3 1.6 9.8 2.5 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF2428 PF10350.9 OAJ16271.1 - 8.6e-49 166.2 0.1 1.7e-48 165.2 0.1 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) DUF3807 PF12720.7 OAJ16272.1 - 0.31 11.3 18.2 0.026 14.8 9.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) TMEM214 PF10151.9 OAJ16272.1 - 2.9 6.2 8.2 4.2 5.7 8.2 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Plasmodium_Vir PF05795.11 OAJ16272.1 - 6.3 6.1 9.0 0.14 11.6 1.6 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein tRNA-synt_2 PF00152.20 OAJ16273.1 - 4.4e-65 219.8 0.0 1.2e-64 218.4 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ16273.1 - 8e-05 22.6 0.0 0.00053 19.9 0.0 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain ORC2 PF04084.14 OAJ16274.1 - 1.5e-37 129.2 0.0 1.1e-32 113.3 0.0 2.6 2 1 0 2 2 2 2 Origin recognition complex subunit 2 PBP1_TM PF14812.6 OAJ16274.1 - 0.0073 16.7 0.6 0.0073 16.7 0.6 6.4 6 1 1 7 7 7 2 Transmembrane domain of transglycosylase PBP1 at N-terminal SQS_PSY PF00494.19 OAJ16275.1 - 1.2e-45 156.1 0.4 1.4e-45 155.9 0.4 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase dCMP_cyt_deam_1 PF00383.23 OAJ16276.1 - 4e-13 49.1 0.2 7.1e-13 48.3 0.2 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAJ16276.1 - 7.5e-11 42.4 2.4 7.1e-10 39.2 0.2 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAJ16276.1 - 1.1e-05 25.1 2.0 0.021 14.4 2.1 2.1 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Herpes_capsid PF06112.11 OAJ16277.1 - 0.35 10.9 3.1 0.52 10.4 3.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Aldose_epim PF01263.20 OAJ16278.1 - 1.5e-55 188.6 0.1 2e-55 188.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase LANC_like PF05147.13 OAJ16279.1 - 0.26 9.8 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Trypan_PARP PF05887.11 OAJ16279.1 - 4.2 7.3 7.6 2.3 8.2 5.5 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Glyco_hydro_16 PF00722.21 OAJ16281.1 - 6.3e-07 29.0 0.1 1.1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Solute_trans_a PF03619.16 OAJ16282.1 - 3.5e-87 292.3 23.8 4.5e-87 291.9 23.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 OAJ16282.1 - 0.83 9.9 8.8 0.025 14.8 1.4 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.13 OAJ16283.1 - 1.2e-33 116.8 0.0 1.5e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ16283.1 - 2.2e-05 24.0 0.0 0.056 12.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ16283.1 - 5.7e-05 23.0 0.0 9.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 OAJ16283.1 - 0.00045 19.9 0.0 0.0007 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 OAJ16283.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAJ16283.1 - 0.0038 17.2 0.0 0.0081 16.1 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 OAJ16283.1 - 0.0047 17.6 0.3 0.0047 17.6 0.3 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peroxidase_2 PF01328.17 OAJ16284.1 - 8.7e-43 147.0 0.0 1.3e-42 146.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 SRP19 PF01922.17 OAJ16293.1 - 1.5e-23 83.5 0.1 2.8e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 SRP19 protein MDH PF02315.16 OAJ16293.1 - 0.11 12.5 2.7 0.56 10.3 0.2 2.3 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Tmemb_9 PF05434.11 OAJ16294.1 - 0.053 13.4 0.7 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 TMEM9 SID-1_RNA_chan PF13965.6 OAJ16294.1 - 0.072 11.5 0.0 0.097 11.1 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Rax2 PF12768.7 OAJ16294.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ribosom_S12_S23 PF00164.25 OAJ16295.1 - 5.4e-33 113.0 0.1 7.2e-33 112.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 tRNA-synt_1b PF00579.25 OAJ16296.1 - 3.3e-60 203.9 0.0 1.5e-59 201.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAJ16296.1 - 5.3e-05 23.0 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Inhibitor_I66 PF16850.5 OAJ16297.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I66 RRF PF01765.19 OAJ16299.1 - 0.00028 20.9 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DUF1866 PF08952.11 OAJ16299.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) Ribosomal_S17e PF00833.18 OAJ16300.1 - 3.8e-59 198.0 0.0 4.6e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 OAJ16301.1 - 2.4e-21 76.0 0.0 4.1e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 zf-CCHC PF00098.23 OAJ16302.1 - 4.2e-21 74.0 24.7 2.6e-08 33.6 2.6 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ16302.1 - 1.5e-06 27.8 16.5 0.019 14.7 1.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ16302.1 - 3e-05 23.9 8.9 0.072 13.1 1.4 3.1 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ16302.1 - 0.00036 20.3 23.6 0.00099 18.9 1.2 3.6 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ16302.1 - 0.056 13.2 0.8 0.056 13.2 0.8 3.2 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Mu-like_Com PF10122.9 OAJ16302.1 - 1.6 8.2 10.1 7.1 6.2 0.3 3.3 2 1 1 3 3 3 0 Mu-like prophage protein Com UDPGT PF00201.18 OAJ16304.1 - 6.5e-12 45.0 0.1 1e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FLYWCH_u PF16662.5 OAJ16305.1 - 0.039 14.0 0.2 0.049 13.7 0.2 1.2 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 Exo70 PF03081.15 OAJ16306.1 - 2.7e-51 174.8 0.0 1.1e-50 172.8 0.0 1.9 1 1 0 1 1 1 1 Exo70 exocyst complex subunit Vps52 PF04129.12 OAJ16306.1 - 0.0013 17.5 0.4 0.003 16.4 0.1 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family Baculo_PEP_C PF04513.12 OAJ16306.1 - 0.011 15.8 0.4 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 OAJ16306.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family COG5 PF10392.9 OAJ16306.1 - 0.059 13.6 0.7 6.7 6.9 0.3 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1419 PF07215.11 OAJ16306.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) FmiP_Thoc5 PF09766.9 OAJ16306.1 - 0.21 10.8 0.1 0.33 10.2 0.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 PDR_CDR PF06422.12 OAJ16308.1 - 0.064 13.2 0.1 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 CDR ABC transporter Sec10 PF07393.11 OAJ16309.1 - 5.7e-79 266.4 0.0 2e-76 257.9 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 OAJ16309.1 - 0.44 10.5 3.2 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 F-box-like Zn_clus PF00172.18 OAJ16310.1 - 1.9e-07 31.1 9.8 3.7e-07 30.2 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_A_exo1 PF01612.20 OAJ16311.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Telomerase_RBD PF12009.8 OAJ16312.1 - 1.5e-41 141.7 0.1 4e-41 140.3 0.1 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OAJ16312.1 - 1.3e-08 34.6 0.0 1.8e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_A_exo1 PF01612.20 OAJ16313.1 - 9.4e-15 54.7 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DNApol_Exo PF18136.1 OAJ16313.1 - 0.021 14.0 0.3 0.035 13.2 0.0 1.5 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain DNA_pol_A_exo1 PF01612.20 OAJ16314.1 - 8.9e-16 58.1 0.0 1.7e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DNApol_Exo PF18136.1 OAJ16314.1 - 0.094 11.8 0.4 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 DNA mitochondrial polymerase exonuclease domain RNB PF00773.19 OAJ16330.1 - 3.7e-54 184.3 0.0 7.2e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain ABC2_membrane PF01061.24 OAJ16331.1 - 2.1e-73 246.2 50.3 8.1e-37 126.7 24.2 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ16331.1 - 3.8e-35 121.4 0.0 2.4e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ16331.1 - 1.5e-18 66.5 7.4 1.7e-16 59.9 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAJ16331.1 - 2.5e-10 40.8 0.0 7.1e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal SMC_N PF02463.19 OAJ16331.1 - 2.3e-05 23.9 0.0 0.0022 17.5 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ16331.1 - 2.9e-05 23.7 0.3 0.016 14.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ16331.1 - 3.6e-05 23.7 0.0 0.015 15.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAJ16331.1 - 6.9e-05 22.8 0.1 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAJ16331.1 - 0.0006 20.2 0.1 0.042 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAJ16331.1 - 0.00083 19.5 0.4 0.68 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 OAJ16331.1 - 0.0013 19.0 0.4 0.52 10.6 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.6 OAJ16331.1 - 0.0013 19.2 0.0 0.05 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ16331.1 - 0.0019 17.8 0.1 0.0084 15.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAJ16331.1 - 0.0025 17.4 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OAJ16331.1 - 0.0087 15.8 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ16331.1 - 0.041 14.0 0.5 3.8 7.6 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAJ16331.1 - 0.046 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ16331.1 - 0.053 14.0 0.0 0.42 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAJ16331.1 - 0.14 12.1 0.4 5.2 7.0 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 OAJ16331.1 - 0.16 12.4 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1440 PF07274.12 OAJ16331.1 - 1.2 9.5 7.0 0.31 11.4 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Gtr1_RagA PF04670.12 OAJ16332.1 - 1.9e-32 112.5 0.0 2.3e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ16332.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ16332.1 - 0.003 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAJ16332.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OAJ16332.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAJ16332.1 - 0.034 13.6 0.0 0.14 11.6 0.0 2.0 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.6 OAJ16332.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 OAJ16333.1 - 1.5e-12 47.1 0.1 1.5e-05 24.7 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAJ16333.1 - 0.037 13.8 0.0 0.19 11.5 0.0 2.3 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain CNDH2_C PF16858.5 OAJ16333.1 - 0.15 11.9 30.5 0.022 14.6 16.7 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Thioredoxin PF00085.20 OAJ16334.1 - 4.9e-18 65.0 0.0 6.6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ16334.1 - 0.0023 18.4 0.0 0.0032 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OAJ16334.1 - 0.036 14.2 0.0 0.059 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 OAJ16334.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Choline_kinase PF01633.20 OAJ16335.1 - 2e-34 119.0 0.0 6.8e-22 78.1 0.0 3.3 3 1 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 OAJ16335.1 - 0.016 15.1 0.1 0.95 9.3 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1b PF00579.25 OAJ16336.1 - 6.4e-71 239.1 0.0 8.4e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF1771 PF08590.10 OAJ16337.1 - 2.3e-21 75.9 6.9 2.3e-21 75.9 6.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ16337.1 - 2.5e-13 50.2 1.2 6.1e-13 48.9 0.3 2.2 2 0 0 2 2 2 1 Smr domain RRF PF01765.19 OAJ16337.1 - 0.032 14.2 0.3 0.061 13.3 0.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Ribosomal_L30_N PF08079.12 OAJ16337.1 - 0.44 10.8 0.2 0.44 10.8 0.2 2.3 3 0 0 3 3 3 0 Ribosomal L30 N-terminal domain Alk_phosphatase PF00245.20 OAJ16339.1 - 1.3e-88 297.8 0.1 1.8e-88 297.3 0.1 1.2 1 0 0 1 1 1 1 Alkaline phosphatase RCC1 PF00415.18 OAJ16340.1 - 5.3e-14 52.6 21.1 0.012 16.3 0.3 8.4 7 3 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ16340.1 - 6.2e-07 29.1 23.4 0.15 11.9 0.1 7.8 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat AAA PF00004.29 OAJ16341.1 - 1.6e-41 141.8 0.0 3.5e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ16341.1 - 6.9e-07 29.0 0.1 1.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAJ16341.1 - 2.8e-05 24.1 0.0 0.00011 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ16341.1 - 9e-05 22.9 0.6 0.0024 18.3 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ16341.1 - 0.00011 22.4 0.0 0.0057 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ16341.1 - 0.00026 21.2 0.0 0.00097 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ16341.1 - 0.0008 18.6 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAJ16341.1 - 0.0036 17.1 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 OAJ16341.1 - 0.014 14.9 0.0 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAJ16341.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ16341.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ16341.1 - 0.033 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAJ16341.1 - 0.043 13.5 0.1 0.18 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAJ16341.1 - 0.046 13.1 0.1 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 OAJ16341.1 - 0.052 13.4 0.0 7.2 6.4 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAJ16341.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 OAJ16341.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OAJ16341.1 - 0.072 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAJ16341.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 OAJ16341.1 - 0.099 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 OAJ16341.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 OAJ16341.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SQS_PSY PF00494.19 OAJ16342.1 - 1.2e-32 113.4 0.0 3.2e-32 112.1 0.0 1.7 1 1 0 1 1 1 1 Squalene/phytoene synthase LAT PF15234.6 OAJ16343.1 - 0.027 14.2 2.0 0.057 13.1 2.0 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4383 PF14325.6 OAJ16343.1 - 4.5 7.6 9.4 1.7 8.9 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) Glutaredoxin PF00462.24 OAJ16344.1 - 3.3e-19 68.9 0.0 4.4e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OAJ16344.1 - 0.00037 20.9 0.0 0.00069 20.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 OAJ16344.1 - 0.00096 19.5 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 OAJ16344.1 - 0.019 15.3 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_7 PF13899.6 OAJ16344.1 - 0.039 14.1 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 OAJ16344.1 - 0.089 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 OAJ16344.1 - 0.09 12.9 0.3 5.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Ribosomal_L32e PF01655.18 OAJ16345.1 - 3.4e-46 156.1 1.5 3.9e-46 155.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_L13 PF00572.18 OAJ16346.1 - 4.1e-11 43.2 0.6 4.7e-09 36.6 0.1 2.8 2 1 0 2 2 2 1 Ribosomal protein L13 TMEM189_B_dmain PF10520.9 OAJ16346.1 - 0.16 12.1 0.2 0.24 11.5 0.2 1.2 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain p450 PF00067.22 OAJ16347.1 - 4.2e-68 230.2 0.0 5.5e-53 180.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Spt20 PF12090.8 OAJ16360.1 - 6.9e-33 114.2 0.0 6.9e-33 114.2 0.0 7.2 5 3 0 5 5 5 2 Spt20 family PPP4R2 PF09184.11 OAJ16360.1 - 3.6 7.1 19.0 12 5.4 19.0 1.9 1 0 0 1 1 1 0 PPP4R2 Myb_DNA-binding PF00249.31 OAJ16361.1 - 1.4e-15 57.2 0.0 5.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ16361.1 - 4.8e-12 45.9 0.0 4e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.10 OAJ16361.1 - 0.0016 18.5 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 2 Ribosome biogenesis protein Nop16 SLIDE PF09111.10 OAJ16361.1 - 0.16 12.0 0.0 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 SLIDE Mis12 PF05859.12 OAJ16362.1 - 9.7e-25 87.2 0.2 1.9e-24 86.3 0.2 1.5 1 1 0 1 1 1 1 Mis12 protein Abhydrolase_3 PF07859.13 OAJ16363.1 - 3e-07 30.5 0.0 5.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ16363.1 - 2.4e-06 28.3 1.6 3.1e-06 28.0 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 OAJ16363.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 OAJ16363.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Peptidase_S10 PF00450.22 OAJ16364.1 - 1.4e-94 317.9 0.0 1.8e-94 317.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase 4HBT_2 PF13279.6 OAJ16365.1 - 0.00078 19.9 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Mtc PF03820.17 OAJ16365.1 - 0.18 10.8 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Tricarboxylate carrier Phage_Coat_B PF05356.11 OAJ16366.1 - 0.11 12.5 1.1 0.94 9.4 1.7 2.1 2 0 0 2 2 2 0 Phage Coat protein B TIM PF00121.18 OAJ16368.1 - 5.7e-92 307.5 0.2 6.5e-92 307.3 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OAJ16368.1 - 0.0082 15.6 0.2 0.15 11.5 0.0 2.1 1 1 1 2 2 2 1 CutC family DUF5403 PF17395.2 OAJ16368.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5403) Cyclin_N PF00134.23 OAJ16369.1 - 2.5e-09 37.0 0.0 5.6e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 Cyclin, N-terminal domain DUF4726 PF15855.5 OAJ16369.1 - 0.039 14.2 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) Exo84_C PF16528.5 OAJ16371.1 - 3.3e-53 180.6 0.3 5.5e-53 179.8 0.3 1.4 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAJ16371.1 - 7.4e-15 54.8 0.4 7.4e-15 54.8 0.4 1.9 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 OAJ16371.1 - 3.1e-06 27.3 0.1 7.3e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 TetR_C_33 PF13305.6 OAJ16371.1 - 0.09 13.5 0.1 0.29 11.9 0.1 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CDK2AP PF09806.9 OAJ16371.1 - 0.2 11.7 3.8 0.24 11.4 2.1 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Pex14_N PF04695.13 OAJ16371.1 - 5.4 7.7 14.0 4.7 7.8 6.2 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5327 PF17261.2 OAJ16371.1 - 9.7 7.0 11.7 31 5.4 7.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5327) CRAL_TRIO PF00650.20 OAJ16372.1 - 4e-29 101.4 0.0 5.5e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ16372.1 - 2.2e-05 24.6 0.0 3.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_S10 PF00450.22 OAJ16374.1 - 5.5e-72 243.5 0.0 1.1e-71 242.5 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase AAA PF00004.29 OAJ16375.1 - 3.8e-34 118.0 0.1 2.3e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ16375.1 - 7.9e-09 35.4 0.1 1.7e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain DUF815 PF05673.13 OAJ16375.1 - 1.9e-06 27.2 0.0 4.3e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAJ16375.1 - 0.00085 19.3 0.3 0.016 15.2 0.1 2.7 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ16375.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ16375.1 - 0.0016 18.9 0.2 0.0071 16.7 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_OB_N PF17758.1 OAJ16375.1 - 0.0016 18.1 0.7 0.014 15.0 0.0 2.8 3 0 0 3 3 3 1 Proteasomal ATPase OB N-terminal domain AAA_22 PF13401.6 OAJ16375.1 - 0.0026 18.0 0.4 0.016 15.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAJ16375.1 - 0.0064 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 OAJ16375.1 - 0.0065 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 OAJ16375.1 - 0.015 14.6 0.0 0.19 11.1 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 OAJ16375.1 - 0.019 15.5 0.0 0.047 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAJ16375.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ16375.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAJ16375.1 - 0.027 13.7 0.2 0.082 12.1 0.1 1.8 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_28 PF13521.6 OAJ16375.1 - 0.065 13.5 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 OAJ16375.1 - 0.089 12.5 0.2 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAJ16375.1 - 0.089 12.0 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 OAJ16375.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAJ16375.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 OAJ16375.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 OAJ16375.1 - 0.23 11.0 0.6 2.3 7.8 0.1 2.7 2 1 0 3 3 3 0 AAA domain AAA PF00004.29 OAJ16376.1 - 2.3e-13 50.7 0.0 6.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ16376.1 - 2.2e-05 24.3 0.0 4.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 OAJ16376.1 - 3.6e-05 23.8 0.1 0.0071 16.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_2 PF07724.14 OAJ16376.1 - 0.00066 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAJ16376.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 OAJ16376.1 - 0.0028 17.9 0.1 0.012 15.9 0.1 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 OAJ16376.1 - 0.0045 17.4 0.0 0.0045 17.4 0.0 2.7 2 2 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ16376.1 - 0.018 15.3 0.0 0.058 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ16376.1 - 0.034 14.3 1.3 0.2 11.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 OAJ16376.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 OAJ16376.1 - 0.048 13.9 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAJ16376.1 - 0.058 13.9 0.0 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAJ16376.1 - 0.083 13.4 0.1 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 OAJ16376.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ16376.1 - 0.15 11.4 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.22 OAJ16376.1 - 0.16 11.1 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ANAPC_CDC26 PF10471.9 OAJ16376.1 - 0.69 10.8 4.4 1.2 10.0 0.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Exo_endo_phos PF03372.23 OAJ16377.1 - 1.6e-15 57.3 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0492 PF15744.5 OAJ16377.1 - 0.035 13.3 8.6 0.045 13.0 8.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 NDK PF00334.19 OAJ16378.1 - 2.2e-29 102.2 0.0 2.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tcf25 PF04910.14 OAJ16379.1 - 9.3e-88 294.6 0.0 1.2e-87 294.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TetR_C_28 PF17937.1 OAJ16379.1 - 0.0055 17.1 1.3 5.2 7.6 0.2 3.2 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Med3 PF11593.8 OAJ16379.1 - 3.2 6.8 11.9 0.037 13.2 3.4 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal LZ_Tnp_IS66 PF13007.7 OAJ16379.1 - 7.4 7.4 8.7 46 4.9 7.3 3.2 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain 6PF2K PF01591.18 OAJ16380.1 - 3.4e-69 232.6 0.0 4.8e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ16380.1 - 3.6e-33 114.9 0.0 6.9e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ16380.1 - 4.3e-07 30.2 0.0 7.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ16380.1 - 0.017 15.6 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 OAJ16380.1 - 0.19 11.0 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain EI24 PF07264.11 OAJ16381.1 - 1.1e-20 74.7 16.1 1.6e-20 74.1 16.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 2OG-FeII_Oxy PF03171.20 OAJ16392.1 - 5.7e-22 78.1 0.0 9.7e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAJ16392.1 - 1.7e-20 73.9 0.0 3.2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PAC4 PF16093.5 OAJ16393.1 - 1.1e-08 35.2 1.7 3.6e-08 33.5 0.2 2.4 2 1 0 2 2 2 1 Proteasome assembly chaperone 4 zf-H2C2_2 PF13465.6 OAJ16394.1 - 1.7e-08 34.5 0.3 1.7e-08 34.5 0.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 OAJ16394.1 - 2.6e-05 24.8 10.7 0.13 12.9 1.2 3.6 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAJ16394.1 - 0.00023 21.4 0.8 0.00023 21.4 0.8 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAJ16394.1 - 0.0084 16.1 0.2 0.0084 16.1 0.2 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 OAJ16394.1 - 0.059 14.2 0.2 0.059 14.2 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger MRP-L46 PF11788.8 OAJ16395.1 - 1e-17 65.0 0.4 1e-17 65.0 0.4 2.9 3 1 0 3 3 3 1 39S mitochondrial ribosomal protein L46 Prenyltrans PF00432.21 OAJ16396.1 - 4.2e-28 96.8 11.8 1.6e-07 30.9 0.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAJ16396.1 - 0.0009 18.4 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain Stonin2_N PF12016.8 OAJ16396.1 - 0.0045 16.5 1.6 0.011 15.3 1.6 1.5 1 0 0 1 1 1 1 Stonin 2 AKAP2_C PF15304.6 OAJ16396.1 - 0.6 9.3 4.6 0.79 9.0 0.2 2.3 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Cullin PF00888.22 OAJ16397.1 - 0.034 12.8 0.0 0.14 10.8 0.0 1.9 1 1 0 1 1 1 0 Cullin family TAF4 PF05236.14 OAJ16397.1 - 0.2 11.4 0.4 0.31 10.8 0.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ABC_tran PF00005.27 OAJ16398.1 - 7.6e-44 149.6 0.0 1.8e-21 77.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ16398.1 - 4e-24 84.5 2.1 4e-24 84.5 2.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ16398.1 - 7.6e-14 52.2 1.9 0.0024 17.7 0.2 4.6 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ16398.1 - 8.7e-13 48.2 0.1 1.2e-05 24.9 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ16398.1 - 1.4e-06 28.0 0.1 0.012 15.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ16398.1 - 4.7e-06 26.7 0.2 0.021 14.9 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ16398.1 - 5.1e-06 26.8 0.0 0.033 14.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAJ16398.1 - 2.3e-05 24.6 1.2 0.0092 16.1 0.0 3.5 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_33 PF13671.6 OAJ16398.1 - 5.6e-05 23.3 0.1 0.87 9.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 OAJ16398.1 - 0.00022 21.2 0.4 0.19 11.6 0.0 2.8 3 0 0 3 3 2 2 NACHT domain RsgA_GTPase PF03193.16 OAJ16398.1 - 0.00025 21.0 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 OAJ16398.1 - 0.00045 20.0 1.3 0.32 10.7 0.0 3.6 3 1 0 4 4 4 1 AAA ATPase domain AAA_24 PF13479.6 OAJ16398.1 - 0.00083 19.1 0.0 0.44 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ16398.1 - 0.00088 19.6 1.7 1.1 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 OAJ16398.1 - 0.0019 18.6 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAJ16398.1 - 0.0048 16.9 0.2 2.7 8.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 OAJ16398.1 - 0.0081 15.2 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OAJ16398.1 - 0.0095 16.5 8.6 0.23 11.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 OAJ16398.1 - 0.016 15.8 0.1 0.68 10.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 OAJ16398.1 - 0.019 15.4 5.3 1.2 9.4 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain T2SSE PF00437.20 OAJ16398.1 - 0.031 13.3 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAJ16398.1 - 0.047 13.0 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 OAJ16398.1 - 0.053 13.0 0.0 8.9 5.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 OAJ16398.1 - 0.066 12.7 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 OAJ16398.1 - 0.067 12.9 4.9 0.63 9.7 0.3 3.7 4 1 0 4 4 4 0 AAA domain ATPase_2 PF01637.18 OAJ16398.1 - 0.1 12.5 0.2 8.1 6.3 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_10 PF12846.7 OAJ16398.1 - 0.1 11.5 0.1 0.95 8.3 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.23 OAJ16398.1 - 0.41 10.7 5.1 0.91 9.6 0.0 3.0 4 0 0 4 4 2 0 Dynamin family DUF1746 PF08508.10 OAJ16399.1 - 1.3e-15 57.7 1.4 2.6e-15 56.8 1.4 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) SYF2 PF08231.12 OAJ16400.1 - 1.8e-45 155.2 4.3 1.8e-45 155.2 4.3 2.3 3 0 0 3 3 3 1 SYF2 splicing factor COQ7 PF03232.13 OAJ16401.1 - 1e-66 223.9 1.0 2.2e-66 222.9 1.0 1.5 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 OAJ16401.1 - 0.035 14.5 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Rubrerythrin Ferritin PF00210.24 OAJ16401.1 - 0.06 13.3 0.5 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Ferritin-like domain ACC_central PF08326.12 OAJ16402.1 - 4.2e-198 660.0 0.0 5.8e-198 659.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAJ16402.1 - 3.1e-166 553.9 0.0 4e-166 553.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAJ16402.1 - 4.9e-53 179.8 0.0 8.6e-53 179.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAJ16402.1 - 2.2e-28 99.0 0.1 6.5e-28 97.5 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ16402.1 - 1.5e-21 76.5 0.0 3.6e-20 72.1 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ16402.1 - 3.7e-15 55.5 0.1 7.6e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ16402.1 - 9e-07 28.6 0.0 2.6e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 OAJ16402.1 - 0.0062 16.5 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 OAJ16402.1 - 0.0083 16.2 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAJ16402.1 - 0.039 13.5 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Response_reg PF00072.24 OAJ16404.1 - 6.4e-07 29.5 0.0 4.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Symplekin_C PF12295.8 OAJ16405.1 - 4.4e-55 186.7 0.1 1.1e-54 185.4 0.1 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 OAJ16405.1 - 2.5e-35 122.2 0.3 4.5e-35 121.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT PF02985.22 OAJ16405.1 - 0.38 11.1 3.0 2.6 8.6 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OAJ16405.1 - 0.69 10.3 8.8 1.1 9.6 0.1 4.3 5 0 0 5 5 5 0 HEAT repeats DUF455 PF04305.14 OAJ16406.1 - 1.4e-91 306.4 0.0 1.9e-91 306.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 OAJ16406.1 - 7.3e-08 32.2 0.3 7.3e-08 32.2 0.3 2.5 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OAJ16406.1 - 0.00076 19.4 0.0 0.0074 16.2 0.0 2.2 1 1 1 2 2 2 1 Rieske-like [2Fe-2S] domain Amidase PF01425.21 OAJ16407.1 - 9.5e-93 311.6 0.0 2.8e-92 310.0 0.0 1.8 2 1 0 2 2 2 1 Amidase MFS_1 PF07690.16 OAJ16418.1 - 1.2e-31 109.9 12.4 2e-31 109.2 12.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.18 OAJ16419.1 - 5.4e-44 150.7 0.1 7.8e-44 150.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein eIF3g PF12353.8 OAJ16420.1 - 1.5e-41 141.7 1.0 2.9e-41 140.8 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAJ16420.1 - 2.5e-18 65.6 0.0 4.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 OAJ16421.1 - 1.1e-05 26.1 0.0 0.00011 22.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase II-binding domain. DUF4054 PF13262.6 OAJ16421.1 - 0.063 13.3 0.2 0.063 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF5326 PF17260.2 OAJ16422.1 - 0.041 14.0 0.5 0.08 13.1 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5326) DUF2235 PF09994.9 OAJ16423.1 - 4.8e-66 223.1 0.0 6.5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) GHMP_kinases_N PF00288.26 OAJ16424.1 - 4e-12 46.2 6.9 4e-12 46.2 6.9 2.9 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ16424.1 - 0.00014 22.1 0.1 0.00037 20.8 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal MOR2-PAG1_C PF14225.6 OAJ16424.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Cell morphogenesis C-terminal BPL_LplA_LipB PF03099.19 OAJ16425.1 - 3e-05 23.9 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GCP_C_terminal PF04130.13 OAJ16426.1 - 1.7e-22 80.3 0.2 6.8e-13 48.7 0.0 3.0 2 1 0 2 2 2 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ16426.1 - 4.9e-17 62.5 0.0 1.6e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal UNC-93 PF05978.16 OAJ16427.1 - 8.1e-05 22.4 4.7 8.1e-05 22.4 4.7 2.8 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAJ16427.1 - 0.0012 17.8 32.9 0.0031 16.5 32.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ComJ PF11033.8 OAJ16427.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) Tim17 PF02466.19 OAJ16428.1 - 2.5e-19 69.7 7.2 3.7e-19 69.1 7.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2235 PF09994.9 OAJ16429.1 - 1.9e-71 240.8 0.0 2.4e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) LIP PF03583.14 OAJ16430.1 - 4.4e-16 59.0 0.0 5.4e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ16430.1 - 0.0086 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2183 PF09949.9 OAJ16430.1 - 0.032 14.5 0.0 0.075 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) CUE PF02845.16 OAJ16431.1 - 3e-12 46.0 0.1 5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 CUE domain LIP PF03583.14 OAJ16433.1 - 1.2e-30 106.8 0.2 1.6e-30 106.4 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Svf1_C PF17187.4 OAJ16434.1 - 9.6e-46 155.6 0.0 1.9e-45 154.7 0.0 1.5 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 OAJ16434.1 - 8.1e-41 139.8 0.0 1.1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain SPRY PF00622.28 OAJ16435.1 - 5.6e-05 23.2 0.0 0.026 14.6 0.0 2.9 2 0 0 2 2 2 2 SPRY domain DUF2235 PF09994.9 OAJ16436.1 - 1.9e-73 247.4 0.0 2.5e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) PAPS_reduct PF01507.19 OAJ16437.1 - 2.7e-18 66.6 0.0 5.7e-08 33.0 0.0 3.2 3 0 0 3 3 3 3 Phosphoadenosine phosphosulfate reductase family Lactamase_B_2 PF12706.7 OAJ16449.1 - 8.9e-21 74.3 0.0 5.2e-15 55.5 0.0 3.3 3 0 0 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ16449.1 - 1.1e-05 25.4 0.0 3.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L34e PF01199.18 OAJ16450.1 - 1e-43 147.6 4.0 1.3e-43 147.2 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 OAJ16450.1 - 0.0048 16.9 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c DUF2199 PF09965.9 OAJ16450.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) FhuF_C PF11575.8 OAJ16450.1 - 0.17 11.9 3.2 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain GAPT PF11770.8 OAJ16451.1 - 0.0061 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) TMEM154 PF15102.6 OAJ16451.1 - 2.4 8.1 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 TMEM154 protein family DUF1848 PF08902.11 OAJ16453.1 - 0.21 11.3 2.2 0.25 11.0 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) DUF1640 PF07798.11 OAJ16454.1 - 4.1e-49 167.0 2.7 6e-49 166.4 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OmpH PF03938.14 OAJ16454.1 - 0.07 13.5 2.0 0.16 12.3 2.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Endonuc_Holl PF10107.9 OAJ16454.1 - 0.18 11.7 0.9 0.33 10.8 0.9 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Rubis-subs-bind PF09273.11 OAJ16454.1 - 0.66 10.7 6.0 12 6.7 0.2 2.7 1 1 1 2 2 2 0 Rubisco LSMT substrate-binding TFIIF_alpha PF05793.12 OAJ16456.1 - 0.06 11.9 0.1 0.06 11.9 0.1 5.8 3 2 1 4 4 4 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DRY_EERY PF09750.9 OAJ16456.1 - 0.11 12.8 6.0 0.28 11.5 3.0 2.7 2 0 0 2 2 2 0 Alternative splicing regulator IF3_N PF05198.16 OAJ16457.1 - 0.0065 16.7 0.1 0.091 13.1 0.1 2.4 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Macoilin PF09726.9 OAJ16457.1 - 0.14 10.7 4.6 0.23 10.0 4.6 1.3 1 0 0 1 1 1 0 Macoilin family Gastrin PF00918.17 OAJ16457.1 - 3.9 8.5 5.6 9.2 7.3 0.2 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Glyco_hydro_85 PF03644.13 OAJ16458.1 - 5.5e-75 252.6 0.0 8.1e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 PrpF PF04303.13 OAJ16459.1 - 2.3e-51 174.9 0.0 3.2e-37 128.4 0.0 2.2 2 0 0 2 2 2 2 PrpF protein SAT PF16073.5 OAJ16459.1 - 0.014 15.1 0.8 0.024 14.4 0.2 1.7 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Ribosomal_L2_C PF03947.18 OAJ16460.1 - 2.8e-50 169.8 3.2 1.3e-49 167.6 3.2 2.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAJ16460.1 - 7e-24 83.6 0.1 1.5e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Senescence PF06911.12 OAJ16461.1 - 1.7e-31 110.0 3.7 3.2e-31 109.1 3.7 1.5 1 0 0 1 1 1 1 Senescence-associated protein DAGK_cat PF00781.24 OAJ16462.1 - 1.1e-19 70.3 0.1 2.7e-19 69.0 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain CAP PF00188.26 OAJ16463.1 - 9.3e-21 75.0 3.5 9.3e-21 75.0 3.5 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family NIPSNAP PF07978.13 OAJ16465.1 - 1.5e-37 127.9 1.7 6.5e-30 103.4 0.2 2.4 2 0 0 2 2 2 2 NIPSNAP rhaM PF05336.13 OAJ16465.1 - 0.2 11.7 1.5 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 L-rhamnose mutarotase DUF2417 PF10329.9 OAJ16466.1 - 3.8e-12 46.1 0.0 8e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Region of unknown function (DUF2417) DUF3951 PF13131.6 OAJ16466.1 - 0.2 11.9 3.9 1.9 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) GCD14 PF08704.10 OAJ16467.1 - 4.6e-73 245.9 5.8 6.5e-37 127.5 1.1 4.1 3 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OAJ16467.1 - 0.0017 18.2 0.0 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Gastrin PF00918.17 OAJ16467.1 - 0.22 12.5 2.6 0.59 11.1 2.6 1.7 1 0 0 1 1 1 0 Gastrin/cholecystokinin family CCDC106 PF15794.5 OAJ16467.1 - 1.1 9.0 5.3 2.2 7.9 5.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ribosomal_S24e PF01282.19 OAJ16468.1 - 5.9e-33 112.7 0.1 1.1e-32 111.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Mito_carr PF00153.27 OAJ16469.1 - 6.6e-42 141.4 7.8 5.8e-16 58.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec39 PF08314.11 OAJ16470.1 - 0.026 13.0 0.3 0.041 12.3 0.3 1.3 1 0 0 1 1 1 0 Secretory pathway protein Sec39 KIP1 PF07765.12 OAJ16470.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 KIP1-like protein Colipase-like PF15083.6 OAJ16481.1 - 0.0028 17.7 2.3 0.0028 17.7 2.3 5.7 4 3 1 5 5 5 2 Colipase-like DUF1744 PF08490.12 OAJ16482.1 - 0.092 11.3 0.2 0.16 10.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) FSA_C PF10479.9 OAJ16482.1 - 7.2 4.6 6.6 9.8 4.2 6.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GWT1 PF06423.12 OAJ16483.1 - 4.9e-34 117.6 0.0 5.4e-32 111.0 0.0 3.5 4 1 0 4 4 4 1 GWT1 DUF4818 PF16089.5 OAJ16483.1 - 0.019 15.4 0.8 0.059 13.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) Presenilin PF01080.17 OAJ16483.1 - 0.06 12.1 0.7 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Presenilin SPX PF03105.19 OAJ16483.1 - 8.9 6.1 16.4 1.6e+02 2.0 16.6 2.3 1 1 0 1 1 1 0 SPX domain PolyA_pol PF01743.20 OAJ16484.1 - 1.2e-23 83.9 0.0 2.3e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAJ16484.1 - 0.00047 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A GRDP-like PF07173.12 OAJ16485.1 - 1.2e-14 55.2 4.8 3.8e-13 50.3 0.1 3.9 3 1 1 4 4 4 2 Glycine-rich domain-containing protein-like Sec7 PF01369.20 OAJ16486.1 - 6.1e-66 221.6 0.0 1e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ16486.1 - 2.9e-11 43.5 0.1 1.6e-07 31.4 0.0 3.7 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5067 PF16729.5 OAJ16486.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) Nop PF01798.18 OAJ16487.1 - 8.2e-71 238.1 0.0 1.5e-70 237.3 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAJ16487.1 - 2.4e-38 131.7 7.9 2.4e-38 131.7 7.9 1.9 2 0 0 2 2 2 1 Prp31 C terminal domain NOA36 PF06524.12 OAJ16487.1 - 1.2 8.4 18.9 2.2 7.5 18.9 1.4 1 0 0 1 1 1 0 NOA36 protein RAP1 PF07218.11 OAJ16488.1 - 2.9 6.1 5.3 3.7 5.7 5.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 OAJ16488.1 - 5.4 5.0 4.5 6.9 4.6 4.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein COesterase PF00135.28 OAJ16489.1 - 1e-89 301.8 0.0 1.3e-89 301.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ16489.1 - 1.3e-10 41.5 1.0 8.9e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ16489.1 - 0.13 11.7 1.1 0.22 11.0 1.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSA_C PF10479.9 OAJ16490.1 - 9.5 4.2 10.1 13 3.7 10.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cpn60_TCP1 PF00118.24 OAJ16491.1 - 3.3e-145 484.5 7.1 3.8e-145 484.3 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAJ16491.1 - 0.061 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glycogen_syn PF05693.13 OAJ16491.1 - 0.14 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase BLM10_mid PF16507.5 OAJ16492.1 - 3.8e-157 524.1 0.0 2.7e-156 521.3 0.0 2.3 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAJ16492.1 - 1.4e-25 89.0 0.4 4.7e-24 84.1 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 OAJ16492.1 - 0.0029 17.9 0.1 0.0077 16.5 0.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 OAJ16492.1 - 0.0074 16.5 0.3 0.59 10.5 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 OAJ16492.1 - 0.0092 16.3 0.1 0.087 13.2 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats AAA_29 PF13555.6 OAJ16492.1 - 0.1 12.3 0.8 0.29 10.9 0.8 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SLX9 PF15341.6 OAJ16494.1 - 1.5e-18 67.4 5.8 3.2e-18 66.4 5.8 1.5 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 GRDP-like PF07173.12 OAJ16495.1 - 5.6e-16 59.5 2.3 7.5e-13 49.3 0.1 3.6 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like UPF0506 PF11703.8 OAJ16496.1 - 1.7 9.1 13.6 13 6.3 12.3 2.3 1 1 1 2 2 2 0 UPF0506 Dickkopf_N PF04706.12 OAJ16496.1 - 3.5 8.2 11.6 10 6.7 11.7 1.8 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Asparaginase PF00710.20 OAJ16511.1 - 5.3e-58 195.7 0.0 1.1e-51 175.1 0.0 2.5 2 0 0 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAJ16511.1 - 6.9e-31 106.8 0.0 2e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 OAJ16511.1 - 8.9e-12 45.3 0.2 1.3e-09 38.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ16511.1 - 2.7e-11 43.5 0.3 2.2e-07 31.0 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ16511.1 - 1.6e-09 38.2 0.0 3.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ16511.1 - 2.2e-06 27.9 1.1 0.0077 16.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 OAJ16511.1 - 5.9e-06 26.2 0.3 0.055 14.0 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Hydantoinase_A PF01968.18 OAJ16513.1 - 9.3e-97 323.8 0.4 1.9e-95 319.5 0.2 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAJ16513.1 - 3e-60 203.0 0.3 7.2e-58 195.2 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region GPI PF06560.11 OAJ16513.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MARVEL PF01284.23 OAJ16514.1 - 2.1e-05 24.6 9.3 2.1e-05 24.6 9.3 1.4 1 1 0 1 1 1 1 Membrane-associating domain Mannosyl_trans4 PF15971.5 OAJ16514.1 - 1.6 8.5 8.0 14 5.5 0.3 3.0 3 0 0 3 3 3 0 DolP-mannose mannosyltransferase TspO_MBR PF03073.15 OAJ16515.1 - 2.3e-40 137.8 12.5 2.7e-40 137.5 12.5 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF2776 PF10951.8 OAJ16515.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) PDH PF02153.17 OAJ16516.1 - 9.4e-15 54.3 0.0 1.9e-14 53.3 0.0 1.5 2 0 0 2 2 2 1 Prephenate dehydrogenase F420_oxidored PF03807.17 OAJ16516.1 - 2.7e-07 31.1 0.0 6.7e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 OAJ16516.1 - 4.3e-05 23.6 0.0 7.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAJ16516.1 - 5.1e-05 23.5 0.0 9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ16516.1 - 0.00048 19.5 0.0 0.00083 18.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAJ16516.1 - 0.0042 16.5 0.0 0.0073 15.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 OAJ16516.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ16516.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 OAJ16518.1 - 2.9e-19 69.6 0.0 1.5e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 OAJ16518.1 - 0.00057 20.3 0.0 0.072 13.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FtsJ PF01728.19 OAJ16519.1 - 1.1e-41 142.9 0.0 1.4e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase HSP9_HSP12 PF04119.12 OAJ16520.1 - 6.5e-19 68.1 4.2 6.5e-19 68.1 4.2 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF1744 PF08490.12 OAJ16521.1 - 6.4e-133 443.2 0.0 9.7e-133 442.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAJ16521.1 - 9.6e-77 258.4 0.0 1.6e-76 257.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAJ16521.1 - 4.3e-12 45.5 0.6 1.8e-10 40.1 0.7 3.2 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAJ16521.1 - 6.5e-09 35.8 0.1 2.3e-08 34.0 0.1 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAJ16521.1 - 1.1e-05 25.5 0.0 4.3e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily LPD14 PF18827.1 OAJ16521.1 - 0.12 12.6 0.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 14 IDO PF01231.18 OAJ16522.1 - 1.4e-36 126.3 0.0 1.9e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Ribonuclease_T2 PF00445.18 OAJ16523.1 - 5.2e-32 111.6 0.0 8.9e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Cyt-b5 PF00173.28 OAJ16524.1 - 1.2e-20 73.4 0.1 2.8e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 OAJ16524.1 - 4.8e-15 56.1 13.7 4.8e-15 56.1 13.7 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-C4_ClpX PF06689.13 OAJ16524.1 - 0.22 11.4 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 ClpX C4-type zinc finger SHMT PF00464.19 OAJ16526.1 - 7.5e-167 554.9 0.0 8.9e-167 554.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OAJ16526.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ16526.1 - 0.095 11.8 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TMEM135_C_rich PF15982.5 OAJ16527.1 - 0.00013 22.5 0.0 0.00031 21.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 IF-2B PF01008.17 OAJ16528.1 - 5.4e-35 121.0 0.2 7.3e-32 110.7 0.0 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family PPP4R2 PF09184.11 OAJ16528.1 - 0.13 11.8 11.4 0.26 10.8 11.4 1.5 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 OAJ16528.1 - 0.39 10.0 13.4 0.69 9.2 13.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ16528.1 - 0.54 8.4 16.4 0.066 11.4 12.4 1.4 2 0 0 2 2 2 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 OAJ16528.1 - 1 9.6 22.2 1.7 8.8 22.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 OAJ16528.1 - 3.5 7.0 18.4 5.5 6.3 18.4 1.2 1 0 0 1 1 1 0 SDA1 Amidase PF01425.21 OAJ16529.1 - 4.6e-57 194.0 1.2 8.8e-55 186.5 0.9 2.1 2 0 0 2 2 2 2 Amidase SecE PF00584.20 OAJ16529.1 - 1.1 9.2 2.9 2.5 8.1 2.9 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF3446 PF11928.8 OAJ16543.1 - 0.51 10.7 10.5 15 6.0 1.6 3.4 2 1 1 3 3 3 0 Early growth response N-terminal domain Podoplanin PF05808.11 OAJ16543.1 - 2.3 8.3 9.4 2 8.5 7.7 1.7 1 1 1 2 2 2 0 Podoplanin Iso_dh PF00180.20 OAJ16544.1 - 2.7e-90 303.1 0.0 5.6e-90 302.0 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Synaptobrevin PF00957.21 OAJ16545.1 - 1.4e-26 92.1 0.1 2.1e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAJ16545.1 - 4.2e-18 65.2 0.0 6.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2476 PF10630.9 OAJ16545.1 - 0.021 14.9 0.3 0.04 14.1 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2476) Arg_decarb_HB PF17810.1 OAJ16548.1 - 0.00058 20.1 0.1 0.00088 19.5 0.1 1.4 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Hamartin PF04388.12 OAJ16549.1 - 0.025 13.3 13.3 0.026 13.2 13.3 1.0 1 0 0 1 1 1 0 Hamartin protein Phage_fiber_2 PF03406.13 OAJ16549.1 - 0.037 13.6 4.2 0.037 13.6 4.2 2.3 2 0 0 2 2 2 0 Phage tail fibre repeat CDC27 PF09507.10 OAJ16549.1 - 0.56 9.5 19.6 0.67 9.3 19.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med3 PF11593.8 OAJ16549.1 - 1.3 8.1 20.7 1.7 7.8 20.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SOG2 PF10428.9 OAJ16549.1 - 3 6.9 21.9 3.6 6.7 21.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 OAJ16549.1 - 3.2 6.3 9.5 3.7 6.1 9.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.12 OAJ16549.1 - 3.3 6.2 16.2 4.4 5.8 16.2 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GREB1 PF15782.5 OAJ16549.1 - 8.5 3.3 12.5 10 3.1 12.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Epiglycanin_TR PF05647.11 OAJ16549.1 - 8.7 6.3 29.7 3.1 7.8 2.1 2.4 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like Gtr1_RagA PF04670.12 OAJ16550.1 - 7.8e-84 280.6 0.0 1.1e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ16550.1 - 1.4e-07 31.7 0.0 3.7e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ16550.1 - 1.3e-06 28.5 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAJ16550.1 - 9.7e-06 25.3 0.1 2.3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Ras family Arf PF00025.21 OAJ16550.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ16550.1 - 0.0011 18.3 1.4 0.48 9.5 0.0 3.0 2 1 1 3 3 3 2 G-protein alpha subunit PduV-EutP PF10662.9 OAJ16550.1 - 0.0094 15.7 0.5 0.041 13.6 0.2 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OAJ16550.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Mucin PF01456.17 OAJ16552.1 - 7.8e-06 25.9 13.0 1e-05 25.5 13.0 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.11 OAJ16552.1 - 0.26 11.8 12.2 0.42 11.1 12.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 OAJ16552.1 - 0.45 8.6 5.0 0.56 8.3 5.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 OAJ16552.1 - 1.1 7.4 16.2 1.6 6.9 16.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Chitin_synth_2 PF03142.15 OAJ16553.1 - 4.3e-246 817.6 0.0 5.6e-246 817.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAJ16553.1 - 2.1e-92 310.5 0.0 6.8e-92 308.8 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.6 OAJ16553.1 - 9.2e-14 51.9 0.0 4.7e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 OAJ16553.1 - 2e-13 50.0 0.0 4.2e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 OAJ16553.1 - 4.6e-13 49.1 0.1 4.3e-11 42.8 0.0 2.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 OAJ16553.1 - 6.6e-13 49.0 3.8 6.6e-13 49.0 3.8 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAJ16553.1 - 4.2e-09 36.4 0.0 5.5e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAJ16553.1 - 1.5e-05 24.6 0.0 3.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Membralin PF09746.9 OAJ16554.1 - 0.37 9.8 2.8 0.52 9.3 2.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF1387 PF07139.11 OAJ16554.1 - 2.2 8.0 14.4 3 7.5 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SOG2 PF10428.9 OAJ16554.1 - 3.4 6.8 24.2 4.2 6.5 24.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SWI-SNF_Ssr4 PF08549.10 OAJ16554.1 - 5.9 5.4 14.1 7.8 5.0 14.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Suf PF05843.14 OAJ16554.1 - 6.1 6.7 15.6 8.5 6.3 15.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF936 PF06075.12 OAJ16554.1 - 8.4 5.2 20.2 13 4.6 20.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) WD40 PF00400.32 OAJ16555.1 - 3.6e-36 122.6 17.8 2.5e-07 31.3 0.3 7.9 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16555.1 - 1.8e-12 47.4 0.0 9.9e-05 22.6 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ16555.1 - 0.00017 20.3 0.0 0.00073 18.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OAJ16555.1 - 0.001 18.1 0.2 0.065 12.2 0.0 3.1 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ16555.1 - 0.0051 16.2 0.0 0.41 9.9 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 OAJ16555.1 - 0.021 13.1 0.0 0.077 11.3 0.0 1.9 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 OAJ16555.1 - 0.062 13.3 0.0 0.98 9.5 0.0 2.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SH3_1 PF00018.28 OAJ16556.1 - 2e-14 52.9 0.2 4.2e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OAJ16556.1 - 4e-13 49.8 0.0 7.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 OAJ16556.1 - 7.7e-11 41.7 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ16556.1 - 1.8e-08 34.4 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ16556.1 - 2.9e-07 30.8 0.1 6.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 OAJ16556.1 - 3.9e-07 29.7 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_Ste50p PF09235.10 OAJ16556.1 - 0.00033 20.8 0.1 0.00066 19.9 0.1 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Peptidase_S15 PF02129.18 OAJ16557.1 - 2.1e-06 27.5 0.1 8.2e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAJ16557.1 - 5.6e-06 26.2 0.1 0.001 18.8 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ16557.1 - 0.00014 21.2 0.0 0.0045 16.3 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 NmrA PF05368.13 OAJ16558.1 - 2.8e-13 50.0 0.0 3.8e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ16558.1 - 1.2e-11 44.8 0.0 4.1e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ16558.1 - 0.0041 16.6 0.1 0.04 13.4 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAJ16558.1 - 0.063 13.7 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TbpB_A PF17484.2 OAJ16558.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.4 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B 3Beta_HSD PF01073.19 OAJ16558.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CCHC PF00098.23 OAJ16559.1 - 1.5e-10 40.7 41.6 5.2e-07 29.5 1.2 5.3 5 0 0 5 5 5 4 Zinc knuckle DDHD PF02862.17 OAJ16572.1 - 2e-26 93.5 0.0 2e-26 93.5 0.0 3.4 3 1 0 3 3 3 1 DDHD domain WWE PF02825.20 OAJ16572.1 - 0.14 12.7 0.9 6.8 7.4 0.2 2.6 2 0 0 2 2 2 0 WWE domain DUF1776 PF08643.10 OAJ16574.1 - 0.023 14.1 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Sad1_UNC PF07738.13 OAJ16575.1 - 8.5e-12 45.2 0.0 4e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal SPX PF03105.19 OAJ16575.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 SPX domain DUF2244 PF10003.9 OAJ16575.1 - 0.11 12.2 1.2 0.23 11.1 1.2 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF1776 PF08643.10 OAJ16576.1 - 0.00066 19.1 0.0 0.02 14.3 0.0 2.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) DUF4732 PF15876.5 OAJ16576.1 - 0.15 12.2 0.0 0.57 10.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4732) adh_short PF00106.25 OAJ16576.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase SelP_N PF04592.14 OAJ16580.1 - 0.2 11.0 10.9 0.3 10.5 10.1 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Abhydrolase_6 PF12697.7 OAJ16581.1 - 7.4e-06 26.7 3.1 7.4e-06 26.7 3.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ16581.1 - 0.0051 16.1 0.0 0.0099 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAJ16581.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 OAJ16581.1 - 0.02 14.6 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ16581.1 - 0.047 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAJ16581.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ16582.1 - 1.4e-05 25.8 5.5 1.4e-05 25.8 5.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ16582.1 - 0.0098 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 OAJ16582.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAJ16583.1 - 0.011 16.3 0.1 0.019 15.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ16583.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAJ16583.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 OAJ16583.1 - 0.097 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3402 PF11882.8 OAJ16584.1 - 6.6e-120 401.3 0.0 2.1e-115 386.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 OAJ16584.1 - 1.5e-61 208.1 0.0 3.6e-61 206.9 0.0 1.6 1 1 0 1 1 1 1 N1221-like protein DnaJ PF00226.31 OAJ16585.1 - 3.7e-17 62.2 0.2 6.7e-17 61.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3325 PF11804.8 OAJ16585.1 - 0.058 13.6 0.9 0.058 13.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Cyt-b5 PF00173.28 OAJ16597.1 - 8.6e-25 86.7 0.0 1.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4908 PF16252.5 OAJ16597.1 - 0.044 13.3 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4908) Y_phosphatase2 PF03162.13 OAJ16598.1 - 1.4e-56 190.6 0.0 2.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ16598.1 - 7.4e-07 29.4 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ16598.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ16598.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4050 PF13259.6 OAJ16598.1 - 0.23 11.7 5.6 1.3 9.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Chromo_shadow PF01393.19 OAJ16599.1 - 2.7e-14 53.0 0.1 1.2e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 OAJ16599.1 - 1.1e-07 31.6 3.9 2.4e-07 30.5 3.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4594 PF15266.6 OAJ16599.1 - 0.02 15.2 7.3 0.038 14.4 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4594) SWIRM-assoc_2 PF16496.5 OAJ16599.1 - 0.14 11.0 3.5 0.18 10.6 3.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CWC25 PF12542.8 OAJ16599.1 - 0.15 13.0 3.5 0.075 13.9 1.1 1.8 2 0 0 2 2 2 0 Pre-mRNA splicing factor RhoGEF PF00621.20 OAJ16600.1 - 1.7e-18 67.5 0.2 2.9e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Ribosomal_60s PF00428.19 OAJ16600.1 - 0.00074 20.0 3.0 0.00074 20.0 3.0 4.4 4 0 0 4 4 4 1 60s Acidic ribosomal protein Macoilin PF09726.9 OAJ16600.1 - 9 4.7 10.4 0.18 10.3 3.0 2.0 2 0 0 2 2 2 0 Macoilin family Ribosomal_L7Ae PF01248.26 OAJ16601.1 - 1.5e-21 76.0 0.2 2.2e-21 75.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ16601.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 ATPase_2 PF01637.18 OAJ16601.1 - 0.075 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SIP1 PF04938.12 OAJ16602.1 - 4.2e-23 82.2 0.3 2e-22 80.0 0.1 1.9 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) WRNPLPNID PF15017.6 OAJ16602.1 - 2.5 9.0 7.6 9.4 7.2 0.2 3.1 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Sox_N PF12444.8 OAJ16602.1 - 3.3 8.9 8.3 0.42 11.8 1.0 2.8 3 0 0 3 3 3 0 Sox developmental protein N terminal Glyco_hydro_35 PF01301.19 OAJ16603.1 - 2.3e-76 257.4 0.0 4.4e-76 256.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAJ16603.1 - 4.3e-40 136.8 0.1 1.1e-26 93.6 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAJ16603.1 - 2e-26 92.9 0.0 3.7e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAJ16603.1 - 4.6e-07 29.3 0.0 1.2e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 OAJ16603.1 - 0.006 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_1 PF00515.28 OAJ16604.1 - 6.6e-17 60.5 10.7 2.8e-06 26.9 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16604.1 - 2.7e-16 58.3 23.3 0.00046 20.1 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ16604.1 - 4.4e-10 40.0 6.4 3.2e-05 24.5 0.2 8.3 6 1 5 11 11 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ16604.1 - 4.7e-10 39.8 26.3 5.7e-06 26.7 0.9 8.1 7 1 3 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ16604.1 - 9.2e-10 38.0 8.0 0.05 13.8 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ16604.1 - 9.8e-10 38.0 1.3 0.013 15.2 0.0 5.8 4 2 4 8 8 8 2 TPR repeat TPR_14 PF13428.6 OAJ16604.1 - 9.5e-09 35.4 41.7 0.011 16.5 0.7 10.7 7 1 4 11 11 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ16604.1 - 1.5e-08 34.5 0.2 1.1 9.8 0.1 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ16604.1 - 1.3e-07 31.1 9.2 0.0083 16.1 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ16604.1 - 2.5e-06 27.7 22.7 0.00021 21.5 0.2 6.4 4 2 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ16604.1 - 3.1e-06 27.3 4.5 1.8 8.9 0.1 5.1 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ16604.1 - 0.0022 18.1 1.9 0.0022 18.1 1.9 4.3 4 1 2 6 6 4 1 Tetratricopeptide repeat Nop14 PF04147.12 OAJ16604.1 - 0.069 11.4 24.5 0.1 10.8 24.5 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_10 PF13374.6 OAJ16604.1 - 0.075 12.9 11.2 0.13 12.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat YL1 PF05764.13 OAJ16604.1 - 0.077 13.1 21.6 0.17 12.0 21.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 OAJ16604.1 - 0.11 12.0 24.9 0.2 11.0 24.9 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ16604.1 - 0.15 10.3 16.5 0.28 9.4 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_20 PF14561.6 OAJ16604.1 - 1.8 9.0 5.6 0.78 10.1 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 OAJ16604.1 - 6.2 5.3 20.3 13 4.2 20.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 OAJ16604.1 - 9.6 4.2 38.0 15 3.5 38.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 OAJ16605.1 - 3.6e-11 43.4 1.0 6e-05 23.7 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16605.1 - 1.9e-05 24.9 0.0 0.051 13.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Wzy_C PF04932.15 OAJ16605.1 - 0.26 10.9 1.7 0.47 10.1 1.7 1.4 1 0 0 1 1 1 0 O-Antigen ligase adh_short PF00106.25 OAJ16606.1 - 3.6e-42 144.0 0.0 5.1e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ16606.1 - 4.8e-22 78.7 0.0 6.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ16606.1 - 1.7e-09 37.9 0.0 2.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ16606.1 - 0.0012 18.3 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAJ16606.1 - 0.0026 17.0 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 OAJ16606.1 - 0.028 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAJ16606.1 - 0.078 13.2 0.1 0.5 10.6 0.0 2.0 1 1 1 2 2 2 0 TrkA-N domain ApbA PF02558.16 OAJ16606.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.6 OAJ16606.1 - 0.11 12.3 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H-binding NAD_Gly3P_dh_N PF01210.23 OAJ16606.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OAJ16606.1 - 0.14 12.7 0.0 0.51 11.0 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_1 PF00561.20 OAJ16607.1 - 2.7e-14 53.5 0.0 1.1e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ16607.1 - 6.7e-14 51.9 0.0 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Cellulase PF00150.18 OAJ16608.1 - 1.1e-15 57.9 0.8 1.6e-15 57.3 0.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_transf_22 PF03901.17 OAJ16609.1 - 1e-82 278.6 12.8 5.6e-65 220.2 6.2 2.2 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 OAJ16609.1 - 0.016 15.4 8.3 0.044 14.0 8.3 1.8 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase PTPRCAP PF15713.5 OAJ16610.1 - 2.6 8.3 15.1 13 6.0 6.3 3.8 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated fn3_2 PF16893.5 OAJ16611.1 - 2.1e-37 127.2 1.9 3.4e-37 126.5 0.1 2.0 2 0 0 2 2 2 1 Fibronectin type III domain CHS5_N PF16892.5 OAJ16611.1 - 1.3e-25 89.1 0.1 2.5e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 OAJ16611.1 - 5.2e-06 26.8 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 OAJ16611.1 - 2.6e-05 24.4 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.7 OAJ16611.1 - 6.1e-05 22.9 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.21 OAJ16611.1 - 0.0028 17.9 0.3 0.011 16.1 0.3 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 OAJ16611.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NPR1_like_C PF12313.8 OAJ16611.1 - 0.05 13.1 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal PIG-U PF06728.13 OAJ16612.1 - 9.9e-89 298.0 5.2 1.2e-88 297.8 5.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U MtrD PF04207.12 OAJ16612.1 - 0.065 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D DEAD PF00270.29 OAJ16613.1 - 1.2e-30 106.6 0.0 2.1e-29 102.5 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ16613.1 - 6.6e-16 58.6 0.0 1.5e-14 54.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ16613.1 - 0.15 12.1 0.0 3.1 7.8 0.0 2.5 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ16613.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Myosin_head PF00063.21 OAJ16615.1 - 2.1e-265 882.2 0.0 8.9e-265 880.1 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 OAJ16615.1 - 1e-06 28.4 2.0 2.3e-06 27.4 2.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 OAJ16615.1 - 5e-05 21.4 142.9 7.4e-05 20.8 129.7 2.2 1 1 1 2 2 2 2 Myosin tail AAA_22 PF13401.6 OAJ16615.1 - 0.16 12.3 0.0 0.16 12.3 0.0 4.4 4 1 1 5 5 5 0 AAA domain IQ PF00612.27 OAJ16615.1 - 0.32 10.9 2.8 0.43 10.5 0.5 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.25 OAJ16627.1 - 8.7e-62 208.9 0.0 1.2e-60 205.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16627.1 - 2.3e-26 92.6 0.0 1.9e-25 89.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ16627.1 - 0.00036 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ16627.1 - 0.0033 16.4 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ16627.1 - 0.096 12.6 2.1 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family NIR_SIR PF01077.22 OAJ16629.1 - 6.2e-46 155.8 0.0 8.8e-39 132.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAJ16629.1 - 1.4e-28 98.5 0.0 3.7e-15 55.5 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAJ16629.1 - 1.1e-25 90.5 0.0 2.3e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAJ16629.1 - 2.8e-09 37.1 0.1 9.3e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg JUPITER PF17054.5 OAJ16629.1 - 1.1 8.7 3.8 20 4.5 1.3 2.4 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter GST_N PF02798.20 OAJ16630.1 - 3.2e-16 59.4 0.0 1.9e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ16630.1 - 6.9e-16 58.4 0.0 1.2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ16630.1 - 3.3e-10 40.1 0.0 6.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OAJ16630.1 - 0.00018 22.2 0.0 0.00034 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OAJ16630.1 - 0.025 14.9 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 OAJ16630.1 - 0.056 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ16630.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NDUF_B7 PF05676.13 OAJ16631.1 - 1.7e-29 101.3 2.1 2e-29 101.1 2.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 OAJ16631.1 - 0.00014 21.8 1.7 0.00019 21.3 1.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MIF4G_like PF09088.11 OAJ16632.1 - 9.2e-66 221.2 0.1 8.1e-65 218.2 0.0 2.5 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 OAJ16632.1 - 3.3e-60 203.8 0.0 7.9e-60 202.6 0.0 1.7 1 0 0 1 1 1 1 MIF4G like Spt4 PF06093.13 OAJ16633.1 - 8.9e-29 99.4 0.1 1e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Skp1 PF01466.19 OAJ16634.1 - 1e-26 92.8 0.6 1.8e-26 92.0 0.6 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAJ16634.1 - 3.8e-10 39.8 0.0 1.1e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 OAJ16634.1 - 0.031 14.5 0.3 7.9 6.8 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain LUD_dom PF02589.15 OAJ16634.1 - 0.089 12.5 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 LUD domain PI-PLC-X PF00388.19 OAJ16636.1 - 1.1e-49 167.8 0.0 1.9e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ16636.1 - 3.2e-38 130.6 0.0 7.5e-38 129.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_8 PF13833.6 OAJ16636.1 - 3.1e-05 23.7 0.2 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair C2 PF00168.30 OAJ16636.1 - 0.0013 19.0 0.0 0.93 9.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain PH_12 PF16457.5 OAJ16636.1 - 0.0014 19.1 0.2 0.0092 16.5 0.1 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain EF-hand_7 PF13499.6 OAJ16636.1 - 0.011 16.1 0.7 0.12 12.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair FmiP_Thoc5 PF09766.9 OAJ16637.1 - 9.4e-27 94.2 13.3 1.2e-26 93.9 13.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 V_ATPase_I PF01496.19 OAJ16637.1 - 0.28 9.1 5.1 0.32 8.9 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 OAJ16637.1 - 4 6.2 5.3 5 5.9 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1729 PF08354.10 OAJ16638.1 - 2.2e-156 520.2 0.0 3.7e-156 519.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 OAJ16638.1 - 1.7e-69 233.6 0.4 3.1e-69 232.7 0.4 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAJ16638.1 - 1.1e-68 230.7 0.0 2.5e-68 229.5 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 OAJ16638.1 - 8.3e-66 222.7 0.2 9.2e-65 219.2 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 OAJ16638.1 - 9e-41 139.1 0.0 1.9e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 OAJ16638.1 - 1.6e-29 103.3 0.0 3.1e-28 99.1 0.0 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 OAJ16638.1 - 5.6e-27 93.7 0.0 1.5e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 OAJ16638.1 - 3.3e-22 79.3 1.5 7.3e-22 78.2 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAJ16638.1 - 8.7e-17 61.2 0.3 1.7e-15 57.1 0.5 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 OAJ16638.1 - 1.2e-15 57.7 0.0 3.8e-15 56.0 0.0 2.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 OAJ16638.1 - 8.7e-09 35.1 0.1 7.8e-06 25.5 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydrat_N PF13452.6 OAJ16638.1 - 2.3e-07 31.0 0.0 1.5e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short_C2 PF13561.6 OAJ16638.1 - 3.3e-07 30.1 0.0 2e-06 27.5 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ16638.1 - 0.00026 21.0 0.2 0.01 15.8 0.0 2.7 2 0 0 2 2 2 1 KR domain Thiolase_N PF00108.23 OAJ16638.1 - 0.027 13.8 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ribosomal_L35p PF01632.19 OAJ16639.1 - 7.4e-13 48.8 3.1 1.4e-12 47.9 3.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 Tropomyosin_1 PF12718.7 OAJ16640.1 - 6.4e-47 159.3 27.2 7.5e-47 159.1 27.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAJ16640.1 - 1.1e-11 44.6 27.3 9.9e-06 25.1 8.3 2.8 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 OAJ16640.1 - 0.00017 21.7 27.3 0.061 13.4 7.5 3.7 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 OAJ16640.1 - 0.0018 18.7 23.4 0.004 17.6 2.6 3.7 2 2 2 4 4 4 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase DHR10 PF18595.1 OAJ16640.1 - 0.0021 18.1 27.4 0.061 13.4 10.0 2.5 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain DUF3450 PF11932.8 OAJ16640.1 - 0.0045 16.3 20.2 0.015 14.7 9.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Spc7 PF08317.11 OAJ16640.1 - 0.0046 15.9 25.4 0.14 11.1 11.8 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF5082 PF16888.5 OAJ16640.1 - 0.0097 16.2 15.5 0.1 12.9 7.3 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF5082) HrpB7 PF09486.10 OAJ16640.1 - 0.014 15.7 20.3 0.036 14.4 4.6 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.8 OAJ16640.1 - 0.016 15.2 25.3 0.55 10.3 7.6 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding GIT_CC PF16559.5 OAJ16640.1 - 0.016 15.1 3.1 0.07 13.0 0.7 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF641 PF04859.12 OAJ16640.1 - 0.017 15.4 3.3 0.017 15.4 3.3 2.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) ERM PF00769.19 OAJ16640.1 - 0.021 14.7 29.9 0.47 10.2 15.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Lebercilin PF15619.6 OAJ16640.1 - 0.021 14.5 26.2 0.45 10.2 11.8 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 OAJ16640.1 - 0.023 14.0 22.5 3.1 7.1 22.5 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 OAJ16640.1 - 0.027 15.0 31.7 0.13 12.8 15.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 OAJ16640.1 - 0.028 14.5 20.9 0.048 13.7 6.4 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase FliD_C PF07195.12 OAJ16640.1 - 0.029 13.8 10.9 0.23 10.9 1.5 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus HisKA_3 PF07730.13 OAJ16640.1 - 0.03 14.8 10.4 1.1 9.8 2.3 3.9 1 1 2 3 3 3 0 Histidine kinase DUF724 PF05266.14 OAJ16640.1 - 0.038 13.8 22.9 0.22 11.4 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Csm1_N PF18504.1 OAJ16640.1 - 0.04 14.2 3.5 0.04 14.2 3.5 3.8 1 1 3 4 4 4 0 Csm1 N-terminal domain ADIP PF11559.8 OAJ16640.1 - 0.053 13.6 24.1 1.2 9.2 5.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 OAJ16640.1 - 0.078 13.0 29.9 2 8.5 7.6 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 OAJ16640.1 - 0.088 13.2 11.5 2.6 8.5 0.2 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 OAJ16640.1 - 0.1 12.6 11.2 0.34 11.0 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 OAJ16640.1 - 0.11 12.1 22.3 0.12 11.9 11.0 2.0 1 1 1 2 2 2 0 Intermediate filament protein Dynamitin PF04912.14 OAJ16640.1 - 0.11 11.8 18.7 0.46 9.7 18.7 2.1 1 1 0 1 1 1 0 Dynamitin EzrA PF06160.12 OAJ16640.1 - 0.13 10.4 19.3 0.02 13.1 8.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GTP-bdg_M PF16360.5 OAJ16640.1 - 0.15 12.7 9.9 0.12 13.0 3.5 3.0 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region Gp58 PF07902.11 OAJ16640.1 - 0.19 10.0 4.9 0.2 9.9 4.9 1.0 1 0 0 1 1 1 0 gp58-like protein Jnk-SapK_ap_N PF09744.9 OAJ16640.1 - 0.23 11.7 27.9 0.41 10.9 9.0 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 OAJ16640.1 - 0.23 11.9 22.7 0.16 12.4 19.6 1.8 1 1 1 2 2 2 0 Fez1 DUF4200 PF13863.6 OAJ16640.1 - 0.29 11.6 25.4 0.48 10.8 5.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 OAJ16640.1 - 0.31 8.5 23.9 0.42 8.1 23.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.12 OAJ16640.1 - 0.35 11.5 14.1 0.29 11.8 1.9 3.3 1 1 2 3 3 3 0 SlyX Striatin PF08232.12 OAJ16640.1 - 0.38 11.3 18.3 20 5.7 18.3 2.1 1 1 0 1 1 1 0 Striatin family CHDCT2 PF08074.11 OAJ16640.1 - 0.39 10.9 9.4 0.083 13.1 3.6 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF4407 PF14362.6 OAJ16640.1 - 0.5 9.7 20.4 2.3 7.5 20.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF919 PF06034.11 OAJ16640.1 - 0.5 10.2 8.1 3 7.8 0.4 2.9 2 2 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) FlxA PF14282.6 OAJ16640.1 - 0.52 10.3 10.5 1.3 9.0 2.1 2.5 1 1 2 3 3 3 0 FlxA-like protein Cep57_CLD PF14073.6 OAJ16640.1 - 0.53 10.3 22.3 0.89 9.6 7.7 2.5 1 1 0 2 2 2 0 Centrosome localisation domain of Cep57 DASH_Hsk3 PF08227.11 OAJ16640.1 - 0.54 10.7 3.1 11 6.4 0.3 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF3435 PF11917.8 OAJ16640.1 - 0.58 9.0 10.2 0.71 8.7 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) V_ATPase_I PF01496.19 OAJ16640.1 - 0.6 8.0 11.8 0.76 7.6 11.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family T3SSipB PF16535.5 OAJ16640.1 - 0.63 10.5 18.7 0.96 9.9 11.9 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB XhlA PF10779.9 OAJ16640.1 - 0.64 10.3 21.4 0.3 11.3 4.1 4.0 1 1 4 5 5 5 0 Haemolysin XhlA DUF4927 PF16279.5 OAJ16640.1 - 0.67 11.0 10.2 0.18 12.8 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4927) NBP1 PF08537.10 OAJ16640.1 - 0.71 9.2 14.4 0.71 9.2 3.0 2.3 1 1 1 2 2 2 0 Fungal Nap binding protein NBP1 Laminin_II PF06009.12 OAJ16640.1 - 0.78 9.7 12.7 4.4 7.3 4.5 2.8 1 1 2 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.20 OAJ16640.1 - 0.88 9.6 21.7 2 8.4 2.0 3.6 1 1 1 3 3 3 0 Prefoldin subunit WXG100 PF06013.12 OAJ16640.1 - 0.9 9.8 8.9 5.1 7.4 3.6 3.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sugarporin_N PF11471.8 OAJ16640.1 - 1.1 9.2 16.9 0.52 10.3 0.7 3.5 3 1 0 3 3 3 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.11 OAJ16640.1 - 1.1 9.4 27.3 4.3 7.5 12.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 OAJ16640.1 - 1.4 7.7 21.2 13 4.5 21.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF16 PF01519.16 OAJ16640.1 - 1.5 9.4 11.3 1.8 9.1 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 OEP PF02321.18 OAJ16640.1 - 1.5 8.6 13.6 0.87 9.4 5.5 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein Fib_alpha PF08702.10 OAJ16640.1 - 1.8 8.8 11.5 2.9 8.1 3.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 OAJ16640.1 - 2.1 7.4 19.6 0.065 12.3 5.0 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 OAJ16640.1 - 2.3 7.5 14.8 1.3 8.4 10.4 2.0 1 1 0 1 1 1 0 FAM76 protein HemX PF04375.14 OAJ16640.1 - 2.6 7.3 16.6 1 8.5 3.8 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4094 PF13334.6 OAJ16640.1 - 2.7 8.5 13.2 0.32 11.4 1.8 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) HHV-5_US34A PF17087.5 OAJ16640.1 - 2.9 8.1 4.3 1.6 9.0 1.2 2.1 2 0 0 2 2 2 0 Herpesvirus US34A protein family HAUS-augmin3 PF14932.6 OAJ16640.1 - 3.3 7.2 21.5 0.73 9.4 14.0 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4795 PF16043.5 OAJ16640.1 - 3.3 7.3 19.2 0.82 9.2 7.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Sec2p PF06428.11 OAJ16640.1 - 3.6 7.6 20.9 5.4 7.1 2.6 3.3 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p MRPL52 PF18699.1 OAJ16640.1 - 3.9 7.7 12.9 3.9 7.7 0.4 3.2 1 1 2 3 3 3 0 Mitoribosomal protein mL52 Swi5 PF07061.11 OAJ16640.1 - 5.4 7.2 21.0 0.78 9.9 1.1 4.0 1 1 3 4 4 4 0 Swi5 DUF5320 PF17253.2 OAJ16640.1 - 5.7 8.1 13.4 3.6 8.7 0.6 3.0 2 1 1 3 3 2 0 Family of unknown function (DUF5320) CSN5_C PF18323.1 OAJ16640.1 - 6.1 7.8 13.2 3.1 8.8 1.5 2.8 1 1 2 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain LPP PF04728.13 OAJ16640.1 - 6.3 7.3 12.6 1.9 8.9 0.4 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 OAJ16640.1 - 7 6.7 24.7 1.1 9.3 10.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Lectin_N PF03954.14 OAJ16640.1 - 7.6 6.3 11.3 47 3.7 0.7 2.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4472 PF14739.6 OAJ16640.1 - 7.6 7.3 20.3 3.3 8.5 7.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Prominin PF05478.11 OAJ16640.1 - 7.6 4.3 7.0 8.8 4.1 7.0 1.0 1 0 0 1 1 1 0 Prominin DUF5446 PF17522.2 OAJ16640.1 - 9.1 6.5 13.5 4.1 7.7 1.7 3.2 1 1 3 4 4 4 0 Family of unknown function (DUF5446) TMF_TATA_bd PF12325.8 OAJ16640.1 - 9.2 6.5 21.4 2.6 8.3 10.3 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding LETM1 PF07766.13 OAJ16641.1 - 1.4e-18 67.2 0.1 4.2e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 LETM1-like protein PRIMA1 PF16101.5 OAJ16641.1 - 2.4 8.2 10.9 1.2 9.2 7.9 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 GST_C_2 PF13410.6 OAJ16643.1 - 5.3e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ16643.1 - 2.8e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ16643.1 - 3.8e-07 30.4 0.0 8.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ16643.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RTP1_C1 PF10363.9 OAJ16644.1 - 0.049 13.8 0.0 0.42 10.8 0.0 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HsbA PF12296.8 OAJ16645.1 - 9e-14 51.9 8.4 1.3e-13 51.4 8.4 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.13 OAJ16645.1 - 0.0016 18.4 0.6 0.0024 17.8 0.5 1.4 1 1 0 1 1 1 1 Chemotaxis phosphatase, CheZ Deltameth_res PF16020.5 OAJ16645.1 - 0.11 12.4 0.1 0.84 9.6 0.1 2.2 2 0 0 2 2 2 0 Deltamethrin resistance DUF5344 PF17279.2 OAJ16645.1 - 0.2 12.2 4.7 2.1 9.0 1.3 3.0 2 1 1 3 3 3 0 Family of unknown function (DUF5344) FIVAR PF07554.13 OAJ16645.1 - 9.4 7.1 13.0 4 8.3 2.2 3.2 2 1 1 3 3 3 0 FIVAR domain Ribosomal_L21p PF00829.21 OAJ16661.1 - 3.7e-18 65.7 1.9 3.4e-13 49.7 2.7 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein DUF1754 PF08555.10 OAJ16662.1 - 4.8e-14 52.9 6.9 4.8e-14 52.9 6.9 1.9 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF5427 PF10310.9 OAJ16662.1 - 0.41 9.5 11.5 0.46 9.4 11.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM199X PF15814.5 OAJ16662.1 - 0.44 9.5 14.1 0.51 9.4 14.1 1.0 1 0 0 1 1 1 0 Protein family FAM199X CCDC106 PF15794.5 OAJ16662.1 - 1.6 8.4 14.8 2.4 7.8 14.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MCM3AP_GANP PF16769.5 OAJ16662.1 - 2 6.6 6.6 2.3 6.3 6.6 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP NPR3 PF03666.13 OAJ16662.1 - 2.6 6.7 11.4 3 6.6 11.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pannexin_like PF12534.8 OAJ16662.1 - 3 6.9 8.8 3.7 6.5 8.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Apt1 PF10351.9 OAJ16662.1 - 5.5 5.7 14.6 6.6 5.5 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SID-1_RNA_chan PF13965.6 OAJ16662.1 - 6.9 5.0 4.8 7.9 4.8 4.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CTNNB1_binding PF08347.11 OAJ16662.1 - 7.6 6.7 13.1 13 6.0 13.1 1.4 1 1 0 1 1 1 0 N-terminal CTNNB1 binding DUF3337 PF11816.8 OAJ16663.1 - 8.3e-33 113.7 0.0 1.4e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAJ16663.1 - 1.1e-21 76.7 21.9 1.2e-05 25.9 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16663.1 - 3.1e-05 24.2 0.0 0.015 15.6 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ16663.1 - 0.0068 15.4 0.0 0.34 9.8 0.0 2.4 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BSP_II PF05432.11 OAJ16663.1 - 0.0094 15.7 2.5 0.02 14.6 2.5 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoside_tran PF01733.18 OAJ16664.1 - 1.2e-21 77.5 6.2 6e-19 68.6 7.5 3.8 2 1 0 2 2 2 1 Nucleoside transporter E1-E2_ATPase PF00122.20 OAJ16664.1 - 0.73 9.3 3.5 0.88 9.1 0.1 2.7 3 0 0 3 3 3 0 E1-E2 ATPase OPT PF03169.15 OAJ16665.1 - 9.3e-131 437.4 0.0 1.4e-130 436.8 0.0 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.7 OAJ16666.1 - 0.00087 19.1 0.1 0.0029 17.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.8 OAJ16666.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) NDUF_B4 PF07225.12 OAJ16667.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Cytochrom_B559 PF00283.19 OAJ16667.1 - 0.095 12.2 0.6 0.14 11.6 0.6 1.2 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Clathrin PF00637.20 OAJ16668.1 - 9.3e-28 96.9 0.1 1.8e-27 96.0 0.1 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-rbx1 PF12678.7 OAJ16668.1 - 0.019 15.2 0.3 0.019 15.2 0.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAJ16668.1 - 0.028 14.2 0.3 0.061 13.1 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 OAJ16668.1 - 0.08 13.8 0.1 0.26 12.2 0.1 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 OAJ16668.1 - 0.86 10.0 3.0 2.8 8.3 0.3 2.6 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 OAJ16668.1 - 1.9 8.6 3.8 0.86 9.7 0.4 2.1 2 0 0 2 2 2 0 RING-type zinc-finger TTL PF03133.15 OAJ16669.1 - 5.4e-43 147.2 0.0 3.5e-30 105.1 0.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family Topoisom_bac PF01131.20 OAJ16670.1 - 8.6e-99 331.3 0.0 1e-98 331.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OAJ16670.1 - 7.3e-19 67.9 0.0 1.4e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Glyco_hydro_63 PF03200.16 OAJ16671.1 - 4e-162 540.4 0.0 3.4e-161 537.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAJ16671.1 - 1.1e-68 231.8 0.3 8.5e-67 225.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAJ16671.1 - 9.5e-06 24.7 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 OAJ16671.1 - 0.096 11.9 0.1 0.4 9.9 0.0 2.1 2 1 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain IHABP4_N PF16174.5 OAJ16672.1 - 0.11 13.1 1.7 0.31 11.7 1.7 1.6 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal TFIIA PF03153.13 OAJ16672.1 - 7.1 6.5 8.8 9.4 6.1 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 OAJ16673.1 - 4.4e-90 302.4 0.0 5.6e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 OAJ16673.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone HLH PF00010.26 OAJ16674.1 - 5.2e-07 29.5 0.0 1.6e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Calc_CGRP_IAPP PF00214.19 OAJ16674.1 - 0.075 13.4 1.1 0.21 12.0 1.1 1.7 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family GREB1 PF15782.5 OAJ16674.1 - 7.7 3.5 10.0 12 2.8 10.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer F-box_4 PF15966.5 OAJ16675.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box MSP1_C PF07462.11 OAJ16676.1 - 0.18 10.5 1.8 0.41 9.3 1.8 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Sec23_trunk PF04811.15 OAJ16677.1 - 1.7e-57 194.8 0.0 5.5e-51 173.5 0.0 2.2 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAJ16677.1 - 1.3e-20 73.1 0.0 2.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAJ16677.1 - 2e-19 70.1 0.0 5.3e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAJ16677.1 - 1.1e-14 54.2 6.3 2.1e-14 53.3 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ16677.1 - 0.00011 22.0 0.2 0.00059 19.7 0.0 2.3 3 0 0 3 3 3 1 Gelsolin repeat LSM PF01423.22 OAJ16678.1 - 1.2e-13 50.6 0.1 1.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DNA_pol_phi PF04931.13 OAJ16679.1 - 0.014 13.5 0.4 0.02 13.0 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TssC PF17541.2 OAJ16679.1 - 0.044 12.6 0.6 0.063 12.1 0.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Spc7 PF08317.11 OAJ16679.1 - 0.46 9.3 4.0 0.78 8.6 4.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AA_kinase PF00696.28 OAJ16694.1 - 3.5e-40 138.1 0.5 4.2e-40 137.9 0.5 1.1 1 0 0 1 1 1 1 Amino acid kinase family Dynamin_N PF00350.23 OAJ16695.1 - 1.2e-41 142.6 0.0 2.4e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAJ16695.1 - 4.8e-05 22.7 0.0 0.00015 21.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 OAJ16695.1 - 0.00013 22.0 0.0 0.00049 20.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 OAJ16695.1 - 0.048 13.4 0.1 0.091 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAJ16695.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Vps52 PF04129.12 OAJ16696.1 - 1.5e-40 139.4 0.0 7.7e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 OAJ16696.1 - 2.2e-05 23.1 0.0 3.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Imm70 PF15601.6 OAJ16696.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 70 FAM176 PF14851.6 OAJ16696.1 - 0.47 10.1 2.7 0.91 9.2 2.7 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 OAJ16696.1 - 2.9 5.9 9.4 4.5 5.3 9.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ16696.1 - 2.9 7.2 8.8 4.3 6.6 8.8 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 OAJ16698.1 - 0.067 11.3 2.6 0.094 10.8 2.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 OAJ16698.1 - 0.73 9.5 5.0 1.1 8.9 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 OAJ16698.1 - 2.4 6.7 4.1 2.7 6.6 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.11 OAJ16699.1 - 3 7.2 4.6 3.2 7.1 4.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein WD40 PF00400.32 OAJ16701.1 - 1.3e-07 32.1 4.0 0.031 15.2 0.0 6.0 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16701.1 - 5.9e-07 29.7 0.0 0.0077 16.5 0.0 5.6 6 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Exonuc_VIII PF06630.11 OAJ16701.1 - 0.031 14.1 0.2 0.081 12.8 0.1 1.7 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Ge1_WD40 PF16529.5 OAJ16701.1 - 0.097 11.6 0.1 4.5 6.1 0.0 3.3 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4663 PF15668.5 OAJ16701.1 - 0.25 10.3 1.3 0.99 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4663) Pyr_redox_2 PF07992.14 OAJ16702.1 - 1.8e-49 168.6 0.0 2.3e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ16702.1 - 1.5e-09 38.3 0.0 1.2e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ16702.1 - 0.0067 15.7 0.1 3.1 7.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ16702.1 - 0.31 10.6 2.1 23 4.4 0.0 3.3 2 1 0 3 3 3 0 FAD dependent oxidoreductase Plasmodium_Vir PF05795.11 OAJ16704.1 - 3 7.2 4.6 3.2 7.1 4.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Sporozoite_P67 PF05642.11 OAJ16705.1 - 0.06 11.4 2.3 0.083 11.0 2.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 OAJ16705.1 - 0.75 9.5 5.0 1.2 8.9 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 OAJ16705.1 - 2.5 6.7 4.1 2.9 6.5 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP_bind_1 PF03029.17 OAJ16707.1 - 1e-82 277.6 0.0 1.5e-80 270.4 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ16707.1 - 0.00049 20.0 0.0 0.072 12.9 0.0 2.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_30 PF13604.6 OAJ16707.1 - 0.0067 16.2 0.0 0.052 13.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ16707.1 - 0.01 16.1 0.9 0.098 12.9 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_31 PF13614.6 OAJ16707.1 - 0.011 15.7 0.0 0.2 11.5 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ16707.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain T2SSE PF00437.20 OAJ16707.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 OAJ16707.1 - 0.017 15.7 0.0 0.038 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAJ16707.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 OAJ16707.1 - 0.026 14.9 0.1 1.3 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ16707.1 - 0.032 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ16707.1 - 0.038 13.3 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 KaiC CbiA PF01656.23 OAJ16707.1 - 0.041 14.0 0.0 0.053 13.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 OAJ16707.1 - 0.052 13.1 0.1 1.2 8.6 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA PF00004.29 OAJ16707.1 - 0.067 13.6 0.0 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAJ16707.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 OAJ16707.1 - 0.11 12.9 0.4 0.39 11.1 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAJ16707.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 OAJ16707.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 OAJ16707.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 OAJ16707.1 - 0.18 11.9 0.0 1.4 9.1 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OAJ16707.1 - 0.18 11.7 0.0 1.1 9.2 0.0 2.2 1 1 0 1 1 1 0 NTPase CAF1A PF12253.8 OAJ16708.1 - 3.5e-22 78.3 8.9 3.5e-22 78.3 8.9 4.2 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Hamartin PF04388.12 OAJ16708.1 - 0.61 8.7 39.3 0.99 8.0 39.3 1.3 1 0 0 1 1 1 0 Hamartin protein AIM5 PF17050.5 OAJ16709.1 - 0.041 14.7 0.0 0.33 11.8 0.0 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria 5 SnoaL_2 PF12680.7 OAJ16710.1 - 0.0012 19.5 0.2 0.017 15.7 0.0 2.5 2 1 1 3 3 3 1 SnoaL-like domain PPR_2 PF13041.6 OAJ16711.1 - 3.8e-14 52.6 0.0 0.0022 18.1 0.0 6.0 5 2 1 6 6 6 4 PPR repeat family PPR_1 PF12854.7 OAJ16711.1 - 2.5e-06 27.1 10.5 0.0013 18.4 0.0 5.3 7 0 0 7 7 7 2 PPR repeat PPR PF01535.20 OAJ16711.1 - 5.2e-06 26.3 13.1 0.069 13.4 0.0 6.4 7 1 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 OAJ16711.1 - 8.4e-06 25.8 0.0 1.8 8.7 0.0 3.7 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OAJ16711.1 - 0.00015 21.2 0.1 0.12 11.7 0.0 3.2 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAJ16711.1 - 0.18 12.7 8.5 43 5.3 0.5 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DAO PF01266.24 OAJ16712.1 - 1.8e-55 189.0 1.6 2.1e-55 188.7 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ16712.1 - 3.7e-05 23.1 0.1 0.011 15.0 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ16712.1 - 0.00011 22.4 0.5 0.00025 21.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ16712.1 - 0.00015 21.1 0.3 0.00059 19.1 0.4 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAJ16712.1 - 0.00032 19.9 0.3 0.00041 19.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAJ16712.1 - 0.0019 17.1 0.7 0.021 13.7 0.8 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 OAJ16712.1 - 0.021 13.9 0.2 1.6 7.7 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAJ16712.1 - 0.033 13.4 0.3 0.056 12.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain MCRA PF06100.11 OAJ16712.1 - 0.085 11.6 0.3 0.11 11.2 0.3 1.1 1 0 0 1 1 1 0 MCRA family HI0933_like PF03486.14 OAJ16712.1 - 0.089 11.5 0.6 3.3 6.3 0.9 2.1 2 0 0 2 2 2 0 HI0933-like protein GAS2 PF02187.17 OAJ16713.1 - 5.4e-12 45.6 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Phage_lysozyme PF00959.19 OAJ16713.1 - 0.028 14.9 0.2 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Phage lysozyme POTRA_1 PF08478.10 OAJ16713.1 - 0.072 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, FtsQ-type NdhN PF11909.8 OAJ16713.1 - 0.096 12.4 0.0 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 NADH-quinone oxidoreductase cyanobacterial subunit N zf-MYND PF01753.18 OAJ16714.1 - 1.7e-10 40.8 11.1 1.7e-10 40.8 11.1 2.9 2 1 0 2 2 2 1 MYND finger SET PF00856.28 OAJ16714.1 - 0.00031 21.2 0.0 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-Mss51 PF13824.6 OAJ16714.1 - 0.26 11.4 10.7 0.26 11.4 3.4 3.2 3 1 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_12 PF11331.8 OAJ16714.1 - 5.3 6.9 7.0 0.69 9.8 1.6 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2 PF00096.26 OAJ16715.1 - 4e-06 27.0 2.8 0.03 14.8 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ16715.1 - 0.0014 19.3 1.7 1.6 9.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger RNA_pol_3_Rpc31 PF11705.8 OAJ16715.1 - 0.002 18.4 13.7 0.002 18.4 13.7 2.9 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 OAJ16715.1 - 0.11 10.8 10.5 0.0093 14.3 5.2 1.8 2 0 0 2 2 2 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 OAJ16715.1 - 0.75 9.5 21.5 0.69 9.6 13.9 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ16715.1 - 3.1 5.9 15.9 0.12 10.6 10.2 1.4 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 OAJ16715.1 - 8.3 5.7 16.4 0.96 8.8 11.5 1.8 2 0 0 2 2 2 0 SDA1 Romo1 PF10247.9 OAJ16716.1 - 3.4e-21 75.4 14.2 4.6e-21 75.0 14.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Sugar_tr PF00083.24 OAJ16716.1 - 0.26 10.1 3.3 0.32 9.8 0.3 1.9 1 1 1 2 2 2 0 Sugar (and other) transporter SMYLE_N PF18615.1 OAJ16716.1 - 0.3 10.6 3.0 0.38 10.3 3.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Gly-zipper_OmpA PF13436.6 OAJ16716.1 - 0.45 10.4 6.2 0.77 9.6 1.6 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Latrophilin PF02354.16 OAJ16716.1 - 0.71 8.9 6.3 0.96 8.4 6.3 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region CCDC53 PF10152.9 OAJ16716.1 - 6.6 7.1 10.7 9.2 6.7 10.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RrnaAD PF00398.20 OAJ16728.1 - 4.9e-59 199.6 0.0 6.7e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAJ16728.1 - 1.6e-07 32.0 0.0 2.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ16728.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 OAJ16728.1 - 3.2e-05 24.5 0.0 6.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ16728.1 - 7.2e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAJ16728.1 - 0.00058 19.4 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 OAJ16728.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 OAJ16728.1 - 0.0013 19.4 0.0 0.0025 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16728.1 - 0.0032 17.3 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16728.1 - 0.0082 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAJ16728.1 - 0.009 15.7 0.0 0.049 13.3 0.0 1.9 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 OAJ16728.1 - 0.049 12.9 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 OAJ16728.1 - 0.053 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 OAJ16728.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 OAJ16728.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 RasGEF PF00617.19 OAJ16729.1 - 5.9e-41 140.6 0.0 1.4e-40 139.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ16729.1 - 6.7e-10 39.1 0.3 1.3e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif S4 PF01479.25 OAJ16730.1 - 4.9e-11 42.2 1.3 4.9e-11 42.2 1.3 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 OAJ16730.1 - 2.1e-06 28.5 0.3 5.1e-06 27.3 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Med26_C PF15693.5 OAJ16731.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Atg14 PF10186.9 OAJ16732.1 - 2.7 7.0 10.3 2.2 7.3 4.7 2.7 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3074 PF11274.8 OAJ16733.1 - 7.7e-42 143.4 0.0 1.1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF5615 PF18480.1 OAJ16733.1 - 0.14 11.9 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5615) UCH PF00443.29 OAJ16734.1 - 1.9e-46 158.7 0.0 2.3e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ16734.1 - 1.2e-10 41.5 3.0 4.5e-09 36.3 3.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAJ16734.1 - 5.2e-09 35.7 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ16734.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ16734.1 - 0.15 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Adaptin_N PF01602.20 OAJ16735.1 - 2.5e-136 455.3 7.3 3.3e-136 454.9 7.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ16735.1 - 1.3e-62 210.6 4.0 1.5e-59 200.7 0.5 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ16735.1 - 7.9e-19 67.8 1.8 2.6e-06 27.7 0.0 6.2 3 1 4 8 8 8 5 HEAT repeats HEAT PF02985.22 OAJ16735.1 - 1.4e-12 46.7 4.0 0.0012 18.9 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 OAJ16735.1 - 1.7e-07 31.6 1.0 0.33 11.5 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Cnd3 PF12719.7 OAJ16735.1 - 1.1e-05 24.9 0.6 0.0032 16.7 0.0 3.0 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OAJ16735.1 - 0.00024 21.2 1.9 0.76 10.0 0.0 4.5 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAJ16735.1 - 0.0014 18.3 0.1 2 7.9 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal Sec7_N PF12783.7 OAJ16735.1 - 0.098 12.6 1.4 0.25 11.2 0.5 2.1 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aminoglyc_resit PF10706.9 OAJ16735.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-C2H2 PF00096.26 OAJ16736.1 - 0.00029 21.1 13.2 0.26 11.8 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ16736.1 - 0.0013 19.1 11.3 0.002 18.5 1.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain FOXP-CC PF16159.5 OAJ16736.1 - 0.053 14.2 1.1 0.12 13.0 0.1 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAJ16736.1 - 0.11 13.4 11.7 12 7.1 8.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger BIR PF00653.21 OAJ16736.1 - 1.5 9.5 6.0 2.7 8.7 3.5 2.3 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain CUE PF02845.16 OAJ16737.1 - 2.4e-08 33.5 0.0 3.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OAJ16737.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Noc2 PF03715.13 OAJ16738.1 - 1.2e-107 359.6 1.5 1.6e-107 359.2 0.3 1.8 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 OAJ16738.1 - 0.014 13.7 33.3 0.18 10.0 0.1 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 OAJ16738.1 - 0.095 12.0 29.5 0.17 11.2 29.5 1.3 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 OAJ16739.1 - 2.4e-10 40.1 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OAJ16739.1 - 1.1e-07 32.4 0.0 1.9 9.5 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box PF00646.33 OAJ16739.1 - 6.9e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ16739.1 - 0.00089 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box UIM PF02809.20 OAJ16739.1 - 0.0014 18.4 9.4 0.17 11.9 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Anillin_N PF16018.5 OAJ16740.1 - 0.088 13.4 1.0 0.65 10.6 0.2 2.9 2 0 0 2 2 2 0 Anillin N-terminus DUF676 PF05057.14 OAJ16741.1 - 0.0099 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OAJ16741.1 - 0.094 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase adh_short PF00106.25 OAJ16742.1 - 3e-38 131.2 0.1 3.6e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ16742.1 - 5.1e-31 108.0 0.0 6.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ16742.1 - 1.5e-06 28.3 0.2 2.3e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAJ16742.1 - 0.00023 21.1 0.2 0.00039 20.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ16742.1 - 0.037 14.7 0.0 0.079 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 OAJ16742.1 - 0.05 13.9 0.2 0.095 13.0 0.1 1.5 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.21 OAJ16742.1 - 0.086 12.1 0.3 0.21 10.8 0.4 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L21e PF01157.18 OAJ16743.1 - 1e-45 153.7 4.4 1.3e-45 153.4 2.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e SURF1 PF02104.15 OAJ16756.1 - 1.5e-38 132.8 0.0 2.6e-38 132.0 0.0 1.4 2 0 0 2 2 2 1 SURF1 family PWWP PF00855.17 OAJ16757.1 - 1.2e-05 25.7 0.5 2.9e-05 24.4 0.5 1.7 1 0 0 1 1 1 1 PWWP domain dUTPase PF00692.19 OAJ16758.1 - 7.2e-45 151.8 0.0 9.8e-45 151.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase Ctr PF04145.15 OAJ16759.1 - 1.2e-36 126.6 0.3 1.8e-36 126.0 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family PE_PPE_C PF12484.8 OAJ16759.1 - 0.11 13.4 0.1 0.27 12.2 0.1 1.6 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal HHV-5_US34A PF17087.5 OAJ16759.1 - 0.12 12.6 0.4 0.12 12.6 0.4 2.2 2 0 0 2 2 2 0 Herpesvirus US34A protein family zf-rbx1 PF12678.7 OAJ16760.1 - 5.6e-13 49.0 2.8 9.8e-13 48.2 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ16760.1 - 6.5e-10 39.2 8.1 1.8e-09 37.7 8.1 1.8 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 OAJ16760.1 - 1.1e-06 28.5 0.9 2.3e-06 27.6 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ16760.1 - 1.2e-06 28.3 3.1 2.5e-06 27.2 3.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ16760.1 - 4.9e-06 26.5 3.1 8.7e-06 25.7 3.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ16760.1 - 9.9e-06 25.3 5.4 9.9e-06 25.3 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ16760.1 - 9.3e-05 22.3 2.5 0.00017 21.5 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ16760.1 - 0.00023 20.9 2.8 0.00044 20.1 2.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAJ16760.1 - 0.00099 18.7 1.9 0.0019 17.8 1.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 OAJ16760.1 - 0.0012 18.7 7.3 0.01 15.7 7.5 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ16760.1 - 0.0026 17.5 2.1 0.0026 17.5 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAJ16760.1 - 0.007 16.5 3.2 0.012 15.8 2.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAJ16760.1 - 0.047 13.9 0.4 0.11 12.7 0.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 OAJ16760.1 - 0.43 10.9 3.9 0.76 10.1 3.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 OAJ16760.1 - 3.4 7.5 4.1 2.4 8.0 2.1 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain NUDIX PF00293.28 OAJ16761.1 - 3.8e-19 69.0 0.2 1.5e-18 67.1 0.2 1.8 1 1 0 1 1 1 1 NUDIX domain Snf7 PF03357.21 OAJ16762.1 - 1.2e-44 152.0 12.9 1.2e-44 152.0 12.9 2.0 2 0 0 2 2 2 1 Snf7 Misat_Tub_SegII PF10644.9 OAJ16762.1 - 0.011 16.0 0.4 0.028 14.7 0.4 1.6 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ribosomal_60s PF00428.19 OAJ16762.1 - 0.17 12.5 8.4 0.13 12.8 3.6 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein TraC PF07820.12 OAJ16762.1 - 0.48 10.8 6.8 4.7 7.6 2.2 2.7 2 0 0 2 2 2 0 TraC-like protein Sin3_corepress PF08295.12 OAJ16762.1 - 0.58 10.3 3.9 0.46 10.6 0.3 2.6 3 1 0 3 3 3 0 Sin3 family co-repressor DUF3138 PF11336.8 OAJ16762.1 - 1.6 7.2 8.7 1.3 7.6 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Dynamitin PF04912.14 OAJ16763.1 - 2.9e-58 198.1 0.0 3.6e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Dynamitin WD40 PF00400.32 OAJ16764.1 - 8.3e-37 124.6 14.7 1.8e-06 28.6 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16764.1 - 8.2e-19 67.7 0.0 0.0028 17.9 0.0 5.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAJ16764.1 - 1.6e-05 24.6 0.1 3.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 OAJ16764.1 - 0.0037 16.0 2.3 0.1 11.2 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAJ16764.1 - 0.0065 15.5 0.0 0.59 9.0 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_S7 PF00177.21 OAJ16765.1 - 2.5e-36 124.6 1.4 3.2e-36 124.2 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e RRS1 PF04939.12 OAJ16766.1 - 1.2e-51 174.8 1.3 1.7e-51 174.3 1.3 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Rad54_N PF08658.10 OAJ16766.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.2 2 0 0 2 2 2 0 Rad54 N terminal K_channel_TID PF07941.11 OAJ16766.1 - 0.4 11.2 9.1 0.88 10.1 9.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Peptidase_S24 PF00717.23 OAJ16767.1 - 8.3e-09 35.3 0.0 1.5e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Aminotran_1_2 PF00155.21 OAJ16768.1 - 5.5e-70 236.4 0.0 7e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ16768.1 - 2.1e-06 26.6 0.0 9.2e-06 24.4 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAJ16768.1 - 1.5e-05 24.2 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ16768.1 - 0.0051 16.1 0.1 0.008 15.5 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAJ16768.1 - 0.01 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 OAJ16768.1 - 0.089 13.3 3.6 0.53 10.8 3.6 2.2 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence Aminotran_1_2 PF00155.21 OAJ16769.1 - 8.5e-90 301.5 0.0 9.7e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Complex1_51K PF01512.17 OAJ16770.1 - 3.4e-48 163.4 0.0 5.8e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAJ16770.1 - 2e-31 107.9 0.2 4e-31 106.9 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAJ16770.1 - 5.6e-07 29.3 0.0 1.5e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 SLBB domain LIAS_N PF16881.5 OAJ16771.1 - 6.1e-15 55.6 0.2 2.4e-14 53.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAJ16771.1 - 1.7e-13 51.3 0.1 2.8e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily GLTSCR1 PF15249.6 OAJ16772.1 - 1.3e-11 44.8 0.3 3.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Conserved region of unknown function on GLTSCR protein Abhydrolase_5 PF12695.7 OAJ16773.1 - 0.1 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family CAP_N PF01213.19 OAJ16776.1 - 3.8e-96 322.3 28.7 3.8e-96 322.3 28.7 4.0 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAJ16776.1 - 1.2e-54 184.1 2.6 1.6e-54 183.8 2.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAJ16776.1 - 0.025 14.3 3.8 0.05 13.3 3.8 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C UCH PF00443.29 OAJ16777.1 - 7.8e-42 143.5 0.0 3.7e-41 141.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ16777.1 - 5.3e-21 74.7 9.2 2.9e-18 65.9 1.5 3.4 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OAJ16777.1 - 6.4e-21 73.9 0.9 2.8e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 OAJ16777.1 - 1.7e-20 72.6 8.8 1e-19 70.1 3.5 3.3 2 1 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 OAJ16777.1 - 4.8e-18 65.8 2.1 2.7e-16 60.1 0.1 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C14 PF00656.22 OAJ16778.1 - 1.6e-60 205.1 0.0 2e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RasGEF PF00617.19 OAJ16793.1 - 2.4e-40 138.6 0.0 3.9e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ16793.1 - 1.8e-06 28.1 0.2 4.7e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAJ16793.1 - 0.0034 17.0 0.0 0.0064 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras family Nop14 PF04147.12 OAJ16793.1 - 1.8 6.7 4.2 4.1 5.5 4.2 1.5 1 0 0 1 1 1 0 Nop14-like family UDPGT PF00201.18 OAJ16794.1 - 6.9e-12 44.9 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Aminotran_1_2 PF00155.21 OAJ16795.1 - 6.2e-33 114.4 0.0 1.2e-32 113.5 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Helicase_C PF00271.31 OAJ16796.1 - 5.9e-22 78.1 0.0 7.6e-21 74.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ16796.1 - 3.7e-21 75.9 0.0 8.8e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ16796.1 - 1.5e-14 54.2 0.0 2.9e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAJ16796.1 - 0.00033 20.4 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase RCC1 PF00415.18 OAJ16797.1 - 3.7e-20 72.3 4.3 2e-05 25.1 0.0 6.8 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ16797.1 - 9.8e-14 50.7 19.1 0.00015 21.4 0.0 6.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 OAJ16797.1 - 0.059 13.6 0.6 0.34 11.2 0.1 2.5 3 0 0 3 3 3 0 Putative heavy-metal chelation zf-AN1 PF01428.16 OAJ16798.1 - 2.1e-16 59.8 17.5 5.9e-11 42.4 5.0 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 OAJ16798.1 - 9.7e-05 22.6 10.4 0.032 14.6 2.4 3.2 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 OAJ16798.1 - 0.0026 18.0 11.2 0.0054 16.9 0.7 2.6 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain DUF753 PF05444.12 OAJ16798.1 - 0.11 12.5 5.7 3.5 7.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF753) C1_4 PF07975.12 OAJ16798.1 - 0.34 11.2 7.3 4.1 7.7 0.1 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain zf-CRD PF17979.1 OAJ16798.1 - 0.59 10.2 5.6 0.45 10.6 0.9 2.1 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Hydrophobin PF01185.18 OAJ16799.1 - 0.03 14.9 7.4 0.37 11.5 6.1 2.0 1 1 1 2 2 2 0 Fungal hydrophobin EB1 PF03271.17 OAJ16800.1 - 7.3e-17 61.3 0.5 1.2e-16 60.6 0.5 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 OAJ16800.1 - 0.00028 21.0 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain ThrE PF06738.12 OAJ16801.1 - 1.3e-55 188.4 4.7 1.3e-55 188.4 4.7 2.4 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ16801.1 - 7.1e-08 32.7 4.3 7.1e-08 32.7 4.3 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Yos1 PF08571.10 OAJ16803.1 - 2.7e-29 101.2 1.7 5.9e-29 100.2 1.7 1.5 1 1 0 1 1 1 1 Yos1-like UDPGT PF00201.18 OAJ16804.1 - 2.4e-12 46.4 0.1 2.9e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 OAJ16804.1 - 0.1 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CCT_2 PF09425.10 OAJ16804.1 - 0.24 11.3 0.7 0.49 10.3 0.7 1.5 1 0 0 1 1 1 0 Divergent CCT motif UDPGT PF00201.18 OAJ16805.1 - 1.8e-13 50.1 0.0 2.8e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase BIR PF00653.21 OAJ16806.1 - 3.9e-30 104.3 1.6 7.7e-22 77.7 1.1 2.9 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain EssA PF10661.9 OAJ16806.1 - 0.032 14.1 0.4 0.032 14.1 0.4 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA CMD PF02627.20 OAJ16808.1 - 0.021 14.9 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family DUF4913 PF16259.5 OAJ16809.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) Conotoxin_I2 PF17557.2 OAJ16810.1 - 0.0083 16.2 1.7 0.26 11.4 0.2 2.2 2 0 0 2 2 2 2 I2-superfamily conotoxins Med9 PF07544.13 OAJ16813.1 - 0.054 13.6 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 EamA PF00892.20 OAJ16813.1 - 0.23 11.6 7.5 0.13 12.5 0.7 2.2 2 0 0 2 2 2 0 EamA-like transporter family TPR_12 PF13424.6 OAJ16814.1 - 7e-13 48.7 13.7 3e-05 24.2 1.9 6.7 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ16814.1 - 1.6e-11 43.7 16.4 5.7e-05 22.9 0.9 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ16814.1 - 2.9e-07 30.1 7.3 1.1 9.5 0.2 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ16814.1 - 0.00026 21.0 3.2 16 6.0 0.1 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ16814.1 - 0.00064 19.8 4.5 1.2 9.2 0.2 4.2 3 2 1 4 4 4 3 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 OAJ16814.1 - 0.00099 18.8 1.9 15 5.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ16814.1 - 0.074 13.7 0.3 19 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_23 PF13476.6 OAJ16814.1 - 0.12 12.9 3.2 1.6 9.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain SHNi-TPR PF10516.9 OAJ16814.1 - 0.14 11.6 5.2 1.4 8.4 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR DUF2615 PF11027.8 OAJ16815.1 - 0.17 12.0 0.1 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.6 OAJ16815.1 - 0.63 9.7 4.6 6.1 6.5 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) EamA PF00892.20 OAJ16815.1 - 0.72 10.0 9.7 0.066 13.4 3.0 2.0 1 1 1 2 2 2 0 EamA-like transporter family FtsX PF02687.21 OAJ16815.1 - 4 8.0 8.3 4.5 7.8 0.6 2.3 2 0 0 2 2 2 0 FtsX-like permease family ABC2_membrane_2 PF12679.7 OAJ16815.1 - 5.5 6.2 7.5 20 4.3 0.1 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein UMP1 PF05348.11 OAJ16816.1 - 9.2e-30 103.3 1.1 1.2e-29 103.0 1.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Sulfotransfer_4 PF17784.1 OAJ16829.1 - 1.3e-46 159.2 0.0 1.8e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 OAJ16829.1 - 6.3e-05 23.5 0.2 0.002 18.6 0.0 2.3 1 1 1 2 2 2 1 Sulfotransferase family Enolase_like_N PF18374.1 OAJ16829.1 - 0.11 11.9 2.3 3 7.3 0.1 2.9 3 0 0 3 3 3 0 Enolase N-terminal domain-like Arylsulfotran_2 PF14269.6 OAJ16830.1 - 3.4e-38 131.7 0.0 5.2e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAJ16830.1 - 9e-11 41.3 0.0 1.7e-10 40.4 0.0 1.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PALP PF00291.25 OAJ16831.1 - 7e-50 170.1 4.5 4.9e-49 167.3 4.2 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 OAJ16831.1 - 0.047 13.5 0.2 0.13 12.1 0.2 1.7 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PA PF02225.22 OAJ16831.1 - 0.17 12.0 2.1 1.2 9.3 0.8 2.4 1 1 1 2 2 2 0 PA domain Abhydrolase_6 PF12697.7 OAJ16831.1 - 1.5 9.4 5.2 2.5 8.7 5.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family OPT PF03169.15 OAJ16832.1 - 1.1e-176 589.1 55.8 1.3e-176 588.9 55.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RabGAP-TBC PF00566.18 OAJ16833.1 - 4.3e-17 62.5 0.0 7.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PARP PF00644.20 OAJ16834.1 - 5.1e-06 26.2 0.5 2.6e-05 23.9 0.5 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pol_alpha_B_N PF08418.10 OAJ16835.1 - 2.9e-38 132.2 0.0 8.4e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 OAJ16835.1 - 8.4e-29 100.4 0.5 1.3e-28 99.8 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CW_binding_2 PF04122.12 OAJ16836.1 - 0.92 10.2 4.3 13 6.5 0.6 3.7 1 1 1 2 2 2 0 Putative cell wall binding repeat 2 bZIP_1 PF00170.21 OAJ16838.1 - 1.6e-05 24.9 3.1 3.7e-05 23.7 3.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ16838.1 - 0.0038 17.3 3.4 0.0038 17.3 3.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper UPF0242 PF06785.11 OAJ16838.1 - 0.58 10.2 5.0 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rho_Binding PF08912.11 OAJ16838.1 - 0.82 10.5 4.2 12 6.8 0.1 2.6 2 0 0 2 2 2 0 Rho Binding Spc24 PF08286.11 OAJ16838.1 - 0.9 9.8 5.8 0.42 10.9 1.0 2.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 YabA PF06156.13 OAJ16838.1 - 1.6 9.4 3.6 3.3 8.4 0.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA LRR_4 PF12799.7 OAJ16840.1 - 6.4e-29 99.5 26.1 1.1e-06 28.9 0.3 6.8 2 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ16840.1 - 9.8e-25 86.1 26.8 5.1e-08 32.6 5.0 6.1 3 1 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 OAJ16840.1 - 2.7e-17 62.8 5.8 6.3e-08 32.3 0.4 4.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 OAJ16840.1 - 1.5e-09 37.1 11.7 0.5 10.6 0.1 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 OAJ16840.1 - 5.2e-07 29.3 24.7 5.2 8.0 0.1 9.6 10 0 0 10 10 10 2 Leucine Rich Repeat Brr6_like_C_C PF10104.9 OAJ16841.1 - 0.0055 16.5 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain BUD22 PF09073.10 OAJ16842.1 - 0.04 13.3 5.9 0.053 12.9 5.9 1.1 1 0 0 1 1 1 0 BUD22 Cytochrome_B PF00033.19 OAJ16842.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b/b6/petB Nop14 PF04147.12 OAJ16842.1 - 1.7 6.8 6.4 1.9 6.6 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 OAJ16842.1 - 5.9 5.9 5.5 8.4 5.4 5.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pox_MCEL PF03291.16 OAJ16843.1 - 5.8e-72 242.6 0.0 8.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OAJ16843.1 - 5.7e-11 43.0 0.0 1.2e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16843.1 - 4e-08 33.3 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16843.1 - 4.8e-08 32.9 0.0 7.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16843.1 - 8.9e-07 29.6 0.0 1.9e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16843.1 - 2.6e-05 24.8 0.0 5.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAJ16843.1 - 0.0065 15.7 0.0 0.024 13.8 0.0 1.7 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 OAJ16843.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PTS_EIIC_2 PF13303.6 OAJ16843.1 - 0.44 9.5 4.7 0.74 8.8 4.7 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FHA PF00498.26 OAJ16844.1 - 1.1e-15 57.7 0.0 2.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ16844.1 - 0.0014 18.9 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LRR_6 PF13516.6 OAJ16845.1 - 1.3e-08 34.2 10.6 2.9 8.2 0.2 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_8 PF13855.6 OAJ16845.1 - 1.1e-05 25.1 12.2 0.034 13.9 1.0 6.3 5 2 1 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 OAJ16845.1 - 1.5e-05 25.3 11.7 1.9 9.0 0.0 6.7 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ16845.1 - 0.0019 18.5 3.1 21 6.2 0.0 5.8 7 1 1 8 8 5 0 Leucine Rich Repeat DUF2052 PF09747.9 OAJ16845.1 - 0.37 10.9 11.8 0.57 10.3 11.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RXT2_N PF08595.11 OAJ16845.1 - 0.78 9.8 4.9 1.2 9.1 4.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OAJ16845.1 - 0.88 9.2 5.6 1.5 8.5 5.6 1.3 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 OAJ16845.1 - 0.91 8.5 9.5 1.2 8.0 9.5 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 OAJ16845.1 - 1.2 7.1 13.6 1.8 6.6 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ16845.1 - 1.7 6.8 11.6 2.2 6.4 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 OAJ16845.1 - 3.6 7.8 14.9 5.7 7.1 14.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 OAJ16845.1 - 3.9 7.2 8.4 7.6 6.3 8.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2457 PF10446.9 OAJ16845.1 - 4.3 6.4 16.8 5.6 6.0 16.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4746 PF15928.5 OAJ16845.1 - 5.6 6.3 11.0 8 5.8 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DHquinase_II PF01220.19 OAJ16846.1 - 3.4e-60 201.7 0.0 4e-60 201.5 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II CS PF04969.16 OAJ16847.1 - 0.00011 23.2 0.2 0.00021 22.3 0.1 1.6 2 0 0 2 2 2 1 CS domain Tub_N PF16322.5 OAJ16847.1 - 0.067 13.6 0.1 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 Tubby N-terminal Forkhead_N PF08430.12 OAJ16847.1 - 0.44 11.2 15.1 0.7 10.5 15.1 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region WD40 PF00400.32 OAJ16848.1 - 5.3e-24 84.0 13.3 3.1e-05 24.7 0.8 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2415 PF10313.9 OAJ16848.1 - 0.0016 18.4 0.2 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Ank_2 PF12796.7 OAJ16849.1 - 3.7e-15 56.3 0.4 6.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ16849.1 - 1.2e-12 48.0 2.7 1.6e-05 25.3 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ16849.1 - 1.7e-09 37.1 0.6 0.0054 17.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAJ16849.1 - 2.1e-09 37.4 6.4 0.00079 19.8 0.3 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OAJ16849.1 - 2.3e-09 37.4 2.8 2.4e-05 24.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) UQ_con PF00179.26 OAJ16850.1 - 4.7e-39 133.2 0.0 6.3e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ16850.1 - 0.074 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Cutinase PF01083.22 OAJ16865.1 - 7.6e-21 74.9 0.0 9e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.12 OAJ16865.1 - 0.0083 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase PE-PPE PF08237.11 OAJ16865.1 - 0.014 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain WD40 PF00400.32 OAJ16866.1 - 0.042 14.7 0.0 0.12 13.3 0.0 1.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DDE_1 PF03184.19 OAJ16867.1 - 2e-19 69.9 0.0 8.3e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ16867.1 - 1.9e-05 24.6 1.8 2.9e-05 24.0 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DUF4604 PF15377.6 OAJ16867.1 - 0.5 10.8 11.7 0.8 10.1 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SPARC_Ca_bdg PF10591.9 OAJ16867.1 - 1.1 9.6 0.0 1.1 9.6 0.0 3.2 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Peptidase_M24 PF00557.24 OAJ16868.1 - 1e-47 162.6 0.0 1.2e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP_sub_h PF10775.9 OAJ16869.1 - 3.2e-23 81.5 1.1 5.3e-23 80.8 1.1 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h HTH_13 PF11972.8 OAJ16869.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Got1 PF04178.12 OAJ16870.1 - 1.6e-26 92.9 11.2 2.4e-26 92.4 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 OAJ16870.1 - 0.071 11.4 4.8 0.075 11.3 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4199 PF13858.6 OAJ16870.1 - 0.24 11.8 0.0 0.24 11.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) CAF1 PF04857.20 OAJ16873.1 - 9.4e-22 77.6 0.0 5.9e-11 42.1 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease VWA_2 PF13519.6 OAJ16874.1 - 3.4e-26 92.0 0.0 1.1e-25 90.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ16874.1 - 1.7e-10 41.5 0.1 2.8e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAJ16874.1 - 9.4e-08 32.1 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 OAJ16874.1 - 0.0017 18.2 9.4 0.0039 17.0 1.8 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif Med13_C PF06333.12 OAJ16874.1 - 0.14 11.4 3.5 0.2 10.9 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain FSA_C PF10479.9 OAJ16874.1 - 0.74 7.9 2.9 1 7.4 2.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Alpha_GJ PF03229.13 OAJ16874.1 - 5.5 7.6 11.8 9.6 6.8 11.8 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Cwf_Cwc_15 PF04889.12 OAJ16874.1 - 8.2 6.1 11.6 2.2 8.0 8.5 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein STE3 PF02076.15 OAJ16875.1 - 2e-66 224.2 2.9 2.5e-66 223.9 2.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor Epiglycanin_C PF14654.6 OAJ16875.1 - 0.032 14.3 0.8 0.1 12.7 0.2 2.0 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region IATP PF04568.12 OAJ16876.1 - 2.3e-12 47.2 0.1 2.8e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP RNA_pol_L_2 PF13656.6 OAJ16877.1 - 3.3e-27 94.1 0.0 4.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ16877.1 - 9.2e-08 31.4 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ANAPC1 PF12859.7 OAJ16878.1 - 1.3e-11 45.1 4.1 1.4e-10 41.9 4.1 2.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 OAJ16878.1 - 1.8 9.2 8.8 14 6.4 0.0 5.0 5 0 0 5 5 5 0 Proteasome/cyclosome repeat ANAPC5 PF12862.7 OAJ16879.1 - 5.7e-15 55.2 1.7 2.8e-14 52.9 1.3 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 OAJ16879.1 - 0.2 12.0 6.1 0.43 10.9 0.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HMGL-like PF00682.19 OAJ16880.1 - 6.7e-46 157.0 0.2 6.7e-45 153.7 0.2 2.3 1 1 0 1 1 1 1 HMGL-like WD40 PF00400.32 OAJ16881.1 - 1.1e-17 64.0 13.6 0.0013 19.5 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16881.1 - 1.5e-08 34.8 0.0 0.67 10.3 0.0 5.8 3 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ16881.1 - 6.1e-06 25.4 0.3 3.4e-05 23.0 0.2 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PAP_assoc PF03828.19 OAJ16882.1 - 2.1e-15 56.7 0.1 4e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ16882.1 - 7e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ16882.1 - 0.00064 19.8 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Glycoprotein PF03409.15 OAJ16884.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein ApoO PF09769.9 OAJ16885.1 - 2.4e-28 98.7 0.8 3.7e-28 98.1 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O Apolipoprotein PF01442.18 OAJ16885.1 - 0.0027 17.6 3.9 0.024 14.5 0.3 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OAJ16885.1 - 0.023 14.8 0.5 0.87 9.7 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.11 OAJ16885.1 - 0.91 9.5 5.3 13 5.9 0.1 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RTA1 PF04479.13 OAJ16886.1 - 1e-46 159.2 7.8 3.3e-36 124.9 1.0 2.6 2 1 1 3 3 3 2 RTA1 like protein NAM-associated PF14303.6 OAJ16886.1 - 3 8.5 7.9 3.1 8.5 1.5 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Baculo_PEP_C PF04513.12 OAJ16899.1 - 0.00019 21.5 10.1 0.0094 16.0 0.3 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus PIN_2 PF10130.9 OAJ16899.1 - 0.0089 16.3 1.1 0.5 10.6 0.1 2.5 2 0 0 2 2 2 1 PIN domain TraC PF07820.12 OAJ16899.1 - 0.064 13.6 0.9 3.7 8.0 0.1 2.8 2 0 0 2 2 2 0 TraC-like protein YkyA PF10368.9 OAJ16899.1 - 0.13 11.9 6.5 0.061 13.0 0.7 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF713 PF05218.14 OAJ16899.1 - 0.14 11.9 0.6 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Phage_int_SAM_6 PF18644.1 OAJ16899.1 - 0.16 12.0 0.5 0.75 9.8 0.0 2.3 2 1 1 3 3 3 0 Phage integrase SAM-like domain APG6_N PF17675.1 OAJ16899.1 - 0.18 12.3 7.1 0.27 11.8 0.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 OAJ16899.1 - 0.21 11.8 7.9 0.063 13.5 1.5 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain UBN_AB PF14075.6 OAJ16899.1 - 0.25 11.1 5.5 2.6 7.7 0.6 2.3 2 0 0 2 2 2 0 Ubinuclein conserved middle domain HAUS-augmin3 PF14932.6 OAJ16899.1 - 0.27 10.8 9.3 0.26 10.8 3.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.6 OAJ16899.1 - 0.3 9.7 5.3 2.8 6.5 0.6 2.1 2 0 0 2 2 2 0 AAA domain Occludin_ELL PF07303.13 OAJ16899.1 - 0.4 11.4 4.4 2.2 9.0 0.5 2.4 2 0 0 2 2 2 0 Occludin homology domain TMPIT PF07851.13 OAJ16899.1 - 0.5 9.6 4.0 8.1 5.6 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 OAJ16899.1 - 1.6 8.5 8.7 3.3 7.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 OAJ16899.1 - 3 7.9 7.6 3.4 7.7 0.3 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Arf PF00025.21 OAJ16900.1 - 1.2e-36 125.8 0.0 6.4e-25 87.6 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OAJ16900.1 - 2.3e-13 50.4 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ16900.1 - 1.3e-12 47.6 0.0 6.2e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 OAJ16900.1 - 8.3e-08 31.9 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ16900.1 - 1.3e-05 25.2 0.0 1.8e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ16900.1 - 2e-05 24.1 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ16900.1 - 3e-05 23.4 0.5 9.4e-05 21.7 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 OAJ16900.1 - 0.0088 16.1 0.6 0.019 15.0 0.5 1.5 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.6 OAJ16900.1 - 0.08 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Toprim_4 PF13662.6 OAJ16900.1 - 0.12 12.8 0.0 0.65 10.5 0.0 2.0 1 1 1 2 2 2 0 Toprim domain IBN_N PF03810.19 OAJ16901.1 - 5.3e-06 26.3 0.1 0.00017 21.4 0.1 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAJ16901.1 - 0.059 13.4 0.1 0.72 9.9 0.0 2.8 2 1 0 2 2 2 0 Exportin 1-like protein Importin_rep_4 PF18808.1 OAJ16901.1 - 0.11 12.8 0.2 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Importin repeat DUF3147 PF11345.8 OAJ16903.1 - 0.094 13.1 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3147) Peptidase_S8 PF00082.22 OAJ16904.1 - 9.7e-38 130.1 0.0 3.4e-37 128.3 0.0 1.9 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ16904.1 - 2.3e-15 57.3 2.2 2.7e-15 57.0 0.3 2.2 2 0 0 2 2 2 1 Fn3-like domain ASH PF15780.5 OAJ16904.1 - 0.00078 19.6 0.4 0.02 15.1 0.6 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF11 PF01345.18 OAJ16904.1 - 0.011 16.0 0.5 0.011 16.0 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF11 Motile_Sperm PF00635.26 OAJ16904.1 - 0.029 14.2 0.3 0.096 12.5 0.3 1.8 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Big_2 PF02368.18 OAJ16904.1 - 0.053 13.4 1.3 0.3 11.0 0.5 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Lipase_3 PF01764.25 OAJ16905.1 - 1.3e-14 54.2 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) MT-A70 PF05063.14 OAJ16906.1 - 1.2e-49 168.5 0.0 1.1e-33 116.6 0.0 2.3 2 0 0 2 2 2 2 MT-A70 DPBB_1 PF03330.18 OAJ16907.1 - 0.046 14.0 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Lytic transglycolase Collagen_mid PF15984.5 OAJ16908.1 - 0.08 12.7 0.7 0.13 12.0 0.7 1.3 1 0 0 1 1 1 0 Bacterial collagen, middle region DUF4677 PF15726.5 OAJ16908.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4677) Peptidase_S8 PF00082.22 OAJ16909.1 - 4.8e-23 81.9 0.1 9.7e-23 80.9 0.1 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ16910.1 - 1.1e-16 61.5 1.0 1.1e-16 61.5 1.0 1.8 2 0 0 2 2 2 1 Fn3-like domain fn3_6 PF17766.1 OAJ16910.1 - 0.00016 21.8 0.3 0.0006 19.9 0.3 2.1 1 1 0 1 1 1 1 Fibronectin type-III domain ASH PF15780.5 OAJ16910.1 - 0.0004 20.5 0.4 0.11 12.7 0.2 2.4 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF11 PF01345.18 OAJ16910.1 - 0.0021 18.3 1.1 0.0021 18.3 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF11 Peptidase_S8 PF00082.22 OAJ16910.1 - 0.0038 16.5 0.2 0.0086 15.4 0.2 1.6 1 0 0 1 1 1 1 Subtilase family DUF916 PF06030.12 OAJ16910.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) N_BRCA1_IG PF16158.5 OAJ16910.1 - 0.084 13.6 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene Motile_Sperm PF00635.26 OAJ16910.1 - 0.12 12.3 0.3 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 MSP (Major sperm protein) domain FAD_binding_4 PF01565.23 OAJ16912.1 - 7.1e-20 71.2 3.5 1.4e-19 70.2 3.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ16912.1 - 0.00032 20.7 0.0 0.00084 19.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Bac_rhamnosid_N PF08531.10 OAJ16912.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Barwin PF00967.17 OAJ16913.1 - 0.026 14.4 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 OAJ16913.1 - 0.072 13.4 0.7 0.35 11.2 0.7 2.1 1 1 1 2 2 2 0 Lytic transglycolase BspA_v PF18220.1 OAJ16914.1 - 0.11 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Adhesin BspA variable domain Alph_Pro_TM PF09608.10 OAJ16914.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) APG6_N PF17675.1 OAJ16916.1 - 0.068 13.7 0.0 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region HNF-1_N PF04814.13 OAJ16916.1 - 0.072 13.7 3.8 0.098 13.3 3.8 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF746 PF05344.11 OAJ16916.1 - 0.1 12.4 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Macoilin PF09726.9 OAJ16916.1 - 1.1 7.8 5.0 1.3 7.5 5.0 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 OAJ16916.1 - 4.5 6.0 6.3 5.3 5.8 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 OAJ16916.1 - 5.9 6.7 7.4 7.8 6.3 7.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sugar_tr PF00083.24 OAJ16917.1 - 3.3e-42 144.9 20.4 3.6e-41 141.5 20.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ16917.1 - 8.7e-15 54.5 37.6 6.3e-09 35.2 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ16917.1 - 2.4e-08 33.0 20.7 7.7e-07 28.0 7.8 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein MMM1 PF10296.9 OAJ16917.1 - 0.00034 19.8 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ATG22 PF11700.8 OAJ16917.1 - 0.00063 18.5 13.9 0.023 13.4 8.1 2.8 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like BT1 PF03092.16 OAJ16917.1 - 0.0011 17.3 3.2 0.28 9.3 0.0 2.8 3 0 0 3 3 3 2 BT1 family DPBB_1 PF03330.18 OAJ16918.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Lytic transglycolase TIG PF01833.24 OAJ16918.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 IPT/TIG domain Barwin PF00967.17 OAJ16919.1 - 0.034 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Barwin family DnaJ PF00226.31 OAJ16930.1 - 1.2e-20 73.3 0.3 2.4e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 OAJ16930.1 - 0.0019 18.3 2.9 0.0036 17.4 2.9 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide DUF4813 PF16072.5 OAJ16930.1 - 0.066 12.9 0.3 0.089 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Gly-zipper_Omp PF13488.6 OAJ16930.1 - 0.24 11.4 7.8 0.55 10.3 7.8 1.5 1 0 0 1 1 1 0 Glycine zipper S-methyl_trans PF02574.16 OAJ16931.1 - 1.1e-53 182.8 0.0 1.3e-53 182.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Aldedh PF00171.22 OAJ16932.1 - 1.3e-131 439.4 0.0 1.5e-131 439.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MARVEL PF01284.23 OAJ16933.1 - 3.8e-05 23.7 7.8 7.1e-05 22.9 7.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain MgtE PF01769.16 OAJ16933.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.1 2 1 0 2 2 2 0 Divalent cation transporter Uteroglobin PF01099.17 OAJ16933.1 - 0.12 12.7 0.3 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 Uteroglobin family Zip PF02535.22 OAJ16933.1 - 0.13 11.4 0.5 0.2 10.9 0.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SLATT_5 PF18160.1 OAJ16933.1 - 0.24 10.7 0.2 0.47 9.7 0.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 EI24 PF07264.11 OAJ16933.1 - 3.2 8.0 11.2 0.3 11.3 5.2 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF805 PF05656.14 OAJ16933.1 - 3.4 8.1 4.7 7.4 7.0 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) zf-C2H2_11 PF16622.5 OAJ16935.1 - 0.0048 16.6 0.7 0.013 15.3 0.7 1.7 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 OAJ16935.1 - 0.017 15.6 9.1 0.02 15.3 0.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zinc_ribbon_2 PF13240.6 OAJ16935.1 - 0.098 12.4 0.3 0.37 10.6 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain GAGA PF09237.11 OAJ16935.1 - 0.1 12.4 1.1 0.77 9.6 0.4 2.5 2 0 0 2 2 2 0 GAGA factor zf-C2H2_4 PF13894.6 OAJ16935.1 - 0.42 11.6 8.1 0.98 10.4 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 OAJ16935.1 - 5.3 7.4 6.3 2.4 8.5 0.3 3.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Dmrt1 PF12374.8 OAJ16935.1 - 6 7.4 10.3 0.75 10.3 4.3 2.5 1 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Vps39_1 PF10366.9 OAJ16936.1 - 7.4e-29 100.2 1.7 1e-28 99.7 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAJ16936.1 - 1.3e-21 77.1 0.9 3.2e-21 75.8 0.3 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAJ16936.1 - 2.1e-13 50.5 0.0 6.6e-05 22.6 0.0 3.4 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.20 OAJ16936.1 - 4e-07 30.0 6.2 0.00011 22.1 0.5 2.8 3 0 0 3 3 3 2 Region in Clathrin and VPS CTP_transf_1 PF01148.20 OAJ16937.1 - 1.3e-67 228.4 18.0 4.3e-63 213.6 13.6 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family Complex1_LYR_2 PF13233.6 OAJ16938.1 - 8.3e-18 64.9 0.3 1.3e-17 64.3 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ16938.1 - 3.4e-09 36.6 0.2 7.4e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arf PF00025.21 OAJ16939.1 - 3.5e-77 257.8 0.0 4e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ16939.1 - 2.1e-15 57.0 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ16939.1 - 7.2e-13 48.5 0.0 7.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OAJ16939.1 - 4.7e-12 45.7 0.8 1.8e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ16939.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ16939.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ16939.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ16939.1 - 0.0011 18.4 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF4185 PF13810.6 OAJ16939.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) RNase_PH PF01138.21 OAJ16940.1 - 5.3e-24 85.2 0.0 9.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 A_deamin PF02137.18 OAJ16941.1 - 2.8e-40 138.8 0.0 4.2e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Methyltransf_31 PF13847.6 OAJ16942.1 - 2.9e-20 72.6 0.0 3.7e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ16942.1 - 8.1e-18 64.9 0.0 1.3e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ16942.1 - 1.1e-15 58.1 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16942.1 - 1.6e-15 57.6 0.0 2.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ16942.1 - 3.1e-11 43.4 0.0 4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ16942.1 - 2.3e-08 33.7 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAJ16942.1 - 3.4e-08 33.5 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAJ16942.1 - 1.4e-05 24.7 0.0 5.1e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OAJ16942.1 - 4.4e-05 22.9 0.0 7.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 OAJ16942.1 - 5.8e-05 22.7 0.0 0.015 14.8 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain UPF0020 PF01170.18 OAJ16942.1 - 0.00027 20.7 0.0 0.00061 19.5 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.6 OAJ16942.1 - 0.00064 19.7 0.0 0.00089 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 OAJ16942.1 - 0.0025 16.9 0.0 0.0075 15.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 OAJ16942.1 - 0.0048 16.0 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_9 PF08003.11 OAJ16942.1 - 0.0093 14.9 0.0 0.018 14.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.10 OAJ16942.1 - 0.0099 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 OAJ16942.1 - 0.021 14.3 0.0 0.052 13.0 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 OAJ16942.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 OAJ16942.1 - 0.034 14.3 0.0 0.059 13.5 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 OAJ16942.1 - 0.044 13.1 0.0 0.32 10.3 0.0 2.0 1 1 0 1 1 1 0 O-methyltransferase domain N6_Mtase PF02384.16 OAJ16942.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase MetW PF07021.12 OAJ16942.1 - 0.14 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 OAJ16942.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PSK PF06404.12 OAJ16943.1 - 0.041 14.9 0.6 0.067 14.2 0.6 1.3 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DUF3112 PF11309.8 OAJ16944.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) HCMV_UL139 PF12507.8 OAJ16944.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein SOG2 PF10428.9 OAJ16944.1 - 0.13 11.5 5.8 0.16 11.1 5.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Asp PF00026.23 OAJ16945.1 - 4.3e-29 101.9 0.0 6.6e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ16945.1 - 0.0038 17.5 1.4 0.1 12.9 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ16945.1 - 0.023 15.3 0.0 2.5 8.8 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease TMEM154 PF15102.6 OAJ16945.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Nitrate_red_gam PF02665.14 OAJ16945.1 - 0.056 13.0 0.3 0.087 12.3 0.3 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit CD34_antigen PF06365.12 OAJ16945.1 - 0.26 10.8 0.1 0.42 10.2 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family LapA_dom PF06305.11 OAJ16945.1 - 0.6 10.0 1.7 1.3 8.9 1.7 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ras PF00071.22 OAJ16946.1 - 3.8e-58 195.6 0.0 4.4e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ16946.1 - 8.9e-23 80.8 0.0 1.2e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ16946.1 - 1.2e-06 28.1 0.0 2.2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ16946.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ16946.1 - 0.0045 16.4 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ16946.1 - 0.075 12.4 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region adh_short_C2 PF13561.6 OAJ16947.1 - 8.9e-42 143.2 0.0 1.3e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ16947.1 - 4.6e-41 140.4 0.0 8.6e-41 139.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ16947.1 - 2.2e-08 34.2 0.0 3.3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2828 PF11443.8 OAJ16948.1 - 1.9e-203 677.1 0.0 2.2e-203 676.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) MMM1 PF10296.9 OAJ16950.1 - 2.2e-69 234.1 0.0 8.6e-48 163.1 0.0 2.2 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 HEAT PF02985.22 OAJ16951.1 - 1.1e-34 115.5 21.1 0.01 16.0 0.0 14.2 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 OAJ16951.1 - 7.6e-33 112.8 10.5 1.4e-11 44.6 0.0 7.1 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 OAJ16951.1 - 7.6e-12 45.5 17.8 0.3 11.6 0.1 8.2 7 1 1 8 8 8 5 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ16951.1 - 3.3e-10 40.4 0.5 0.092 13.3 0.1 6.7 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ16951.1 - 3.1e-07 30.6 9.2 0.016 15.3 0.1 5.2 4 2 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ16951.1 - 0.00018 20.2 7.2 0.0097 14.5 0.5 4.4 4 1 0 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.8 OAJ16951.1 - 0.00092 18.8 0.9 0.033 13.8 0.1 3.7 1 1 3 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 OAJ16951.1 - 0.01 16.0 3.4 9.6 6.4 0.1 4.1 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 M11L PF11099.8 OAJ16951.1 - 0.028 14.7 0.4 2.1 8.6 0.1 2.9 2 1 0 2 2 2 0 Apoptosis regulator M11L like DNA_pol_B PF00136.21 OAJ16952.1 - 2.2e-98 330.0 0.0 2.8e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ16952.1 - 4.4e-27 95.1 0.0 2e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ16952.1 - 1.3e-11 44.8 5.8 2.7e-11 43.8 5.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta ThiF PF00899.21 OAJ16962.1 - 9.7e-26 90.6 0.0 1.4e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family WD40 PF00400.32 OAJ16963.1 - 3.5e-13 49.8 15.1 0.00016 22.4 0.2 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat GP67 PF17634.2 OAJ16963.1 - 0.0029 18.0 4.8 0.0029 18.0 4.8 5.0 3 1 2 5 5 5 1 Gene product 67 Es2 PF09751.9 OAJ16964.1 - 4.4e-72 244.2 20.1 4.6e-71 240.8 20.1 2.0 1 1 0 1 1 1 1 Nuclear protein Es2 TMEM239 PF15841.5 OAJ16965.1 - 0.13 12.2 1.2 0.94 9.4 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 239 family DUF2157 PF09925.9 OAJ16965.1 - 5.1 6.9 8.7 1.2 9.0 1.9 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF3792 PF12670.7 OAJ16965.1 - 6.1 7.0 14.4 7.8 6.7 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) KilA-N PF04383.13 OAJ16966.1 - 0.0011 18.8 0.0 1.3 8.9 0.0 2.4 1 1 1 2 2 2 2 KilA-N domain PAP_central PF04928.17 OAJ16967.1 - 6.1e-99 330.0 0.0 8e-99 329.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAJ16967.1 - 5.4e-50 169.3 0.0 1e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAJ16967.1 - 3.1e-11 43.4 0.0 9.1e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ16967.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ATP13 PF12921.7 OAJ16967.1 - 0.1 12.4 0.2 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase expression Mcp5_PH PF12814.7 OAJ16968.1 - 1.4e-42 144.7 0.0 2.7e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Amidinotransf PF02274.17 OAJ16968.1 - 0.0013 17.9 1.1 0.0013 17.9 1.1 2.2 2 0 0 2 2 2 1 Amidinotransferase PH PF00169.29 OAJ16968.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 PH domain Thiolase_N PF00108.23 OAJ16969.1 - 1.6e-79 266.9 1.6 2.1e-79 266.5 1.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ16969.1 - 2.6e-48 162.7 0.3 6.8e-48 161.4 0.3 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ16969.1 - 4.6e-05 23.1 2.8 9.1e-05 22.2 1.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain S1 PF00575.23 OAJ16970.1 - 5.8e-35 119.5 18.8 2.9e-08 33.9 0.3 9.9 10 1 0 10 10 10 7 S1 RNA binding domain Suf PF05843.14 OAJ16970.1 - 8.6e-11 42.3 5.1 4e-05 23.8 0.0 3.1 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OAJ16970.1 - 1.3e-06 28.8 0.0 1.1 9.8 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 OAJ16970.1 - 6.2e-06 25.6 3.5 6.6e-05 22.2 1.2 2.6 1 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 OAJ16970.1 - 2.3e-05 25.0 0.7 0.0061 17.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ16970.1 - 3.7e-05 24.2 2.1 15 6.7 0.0 6.3 3 1 3 6 6 6 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 OAJ16970.1 - 0.00012 21.9 4.7 2.2 8.3 0.0 6.3 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain TPR_15 PF13429.6 OAJ16970.1 - 0.00089 18.6 1.5 0.0044 16.3 1.3 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF2110 PF09883.9 OAJ16970.1 - 0.0045 16.6 2.0 2.5 7.6 0.0 4.4 4 1 1 5 5 5 1 Uncharacterized protein conserved in archaea (DUF2110) DUF719 PF05334.13 OAJ16970.1 - 0.03 14.5 0.0 0.03 14.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF719) TPR_6 PF13174.6 OAJ16970.1 - 0.13 12.9 4.1 2.5 8.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SAPS PF04499.15 OAJ16970.1 - 5.9 5.6 20.1 1.3 7.7 1.4 2.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein 7TM_GPCR_Sru PF10322.9 OAJ16971.1 - 0.11 11.7 3.2 0.087 12.1 0.4 2.1 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF4149 PF13664.6 OAJ16971.1 - 0.7 10.2 8.8 4.6 7.6 1.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Methyltransf_11 PF08241.12 OAJ16972.1 - 9.4e-20 71.1 0.0 2.1e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ16972.1 - 6e-19 68.6 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ16972.1 - 2.2e-14 53.5 0.0 3.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ16972.1 - 5.4e-11 43.1 0.0 9.3e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ16972.1 - 4.9e-10 39.1 0.0 7.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAJ16972.1 - 1.2e-09 38.2 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAJ16972.1 - 0.0016 17.9 0.0 0.0067 15.9 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase TPMT PF05724.11 OAJ16972.1 - 0.0019 17.9 0.0 0.0059 16.3 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.16 OAJ16972.1 - 0.0022 16.6 0.0 0.0029 16.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 OAJ16972.1 - 0.0026 17.3 0.0 0.0056 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 OAJ16972.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 OAJ16972.1 - 0.027 13.9 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 OAJ16972.1 - 0.044 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase tRNA_U5-meth_tr PF05958.11 OAJ16972.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 OAJ16972.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain QRPTase_C PF01729.19 OAJ16973.1 - 4.1e-44 150.3 0.3 5.6e-44 149.9 0.3 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAJ16973.1 - 5e-18 64.9 0.0 2.4e-17 62.7 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Lung_7-TM_R PF06814.13 OAJ16974.1 - 6.7e-51 173.3 17.8 1.1e-50 172.6 17.8 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF3671 PF12420.8 OAJ16974.1 - 0.17 12.0 2.8 0.55 10.3 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function PepSY_TM PF03929.16 OAJ16974.1 - 0.81 9.3 13.2 2.2 7.9 12.1 2.2 1 1 0 1 1 1 0 PepSY-associated TM region YlaC PF10777.9 OAJ16974.1 - 5.7 6.8 8.5 9 6.1 3.8 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC ASFV_L11L PF05293.11 OAJ16974.1 - 6.1 7.3 7.7 1.6 9.1 0.6 2.6 2 0 0 2 2 2 0 African swine fever virus (ASFV) L11L protein CN_hydrolase PF00795.22 OAJ16975.1 - 3.8e-21 75.6 0.0 4.1e-07 29.6 0.0 3.0 3 0 0 3 3 3 3 Carbon-nitrogen hydrolase DUF2408 PF10303.9 OAJ16977.1 - 0.016 15.8 1.5 0.016 15.8 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 OAJ16977.1 - 0.034 14.2 1.4 0.072 13.1 0.9 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus P35 PF02331.15 OAJ16977.1 - 0.043 13.2 0.9 0.065 12.6 0.9 1.4 1 1 0 1 1 1 0 Apoptosis preventing protein PSD4 PF07631.11 OAJ16977.1 - 0.12 12.9 2.9 9.3 6.8 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) ApoLp-III PF07464.11 OAJ16977.1 - 0.16 12.1 6.4 0.11 12.6 4.8 1.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) MOZART1 PF12554.8 OAJ16977.1 - 0.17 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF948 PF06103.11 OAJ16977.1 - 2.3 8.6 5.3 13 6.2 5.3 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FTHFS PF01268.19 OAJ16978.1 - 2.3e-257 854.7 0.1 6.4e-257 853.2 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAJ16978.1 - 3e-62 208.7 0.4 3e-62 208.7 0.4 2.7 4 0 0 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAJ16978.1 - 3.3e-32 111.2 0.0 8.6e-32 109.8 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain NUDIX PF00293.28 OAJ16979.1 - 2.3e-15 56.8 0.1 3.8e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 NUDIX domain KH_8 PF17903.1 OAJ16990.1 - 6.1e-32 109.6 0.0 1.2e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAJ16990.1 - 4.6e-05 23.2 0.2 0.00013 21.7 0.0 1.8 2 0 0 2 2 2 1 KH domain COesterase PF00135.28 OAJ16991.1 - 2.8e-60 204.6 0.7 2.9e-48 165.0 0.8 3.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ16991.1 - 0.00044 20.2 0.0 0.0027 17.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L17 PF01196.19 OAJ16992.1 - 3.9e-27 95.0 0.0 1.5e-26 93.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 SH3_16 PF18348.1 OAJ16992.1 - 0.094 12.5 0.2 0.29 11.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain MDMPI_C PF07398.11 OAJ16992.1 - 7.4 7.5 12.3 0.11 13.4 0.7 3.6 3 1 1 4 4 4 0 MDMPI C-terminal domain PP-binding PF00550.25 OAJ16993.1 - 2e-15 56.9 0.1 2.8e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAJ16993.1 - 5.4e-07 29.8 0.1 7.9e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier FlaC_arch PF05377.11 OAJ16993.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1493 PF07377.12 OAJ16993.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DUF1459 PF07312.11 OAJ16993.1 - 0.5 10.6 5.1 0.83 9.9 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) RhoGEF PF00621.20 OAJ16994.1 - 3.6e-40 138.1 0.0 5.5e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 OAJ16994.1 - 2.6e-08 33.5 0.1 0.0021 17.8 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ16994.1 - 3.2e-07 30.5 0.2 3.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ16994.1 - 0.036 14.1 0.6 3.5 7.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 OAJ16994.1 - 0.053 14.1 0.4 28 5.8 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat NB-ARC PF00931.22 OAJ16995.1 - 0.00024 20.4 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 OAJ16995.1 - 0.00096 19.3 0.3 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ16995.1 - 0.0067 17.0 0.0 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAJ16995.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 OAJ16995.1 - 0.044 14.2 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ16995.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAJ16995.1 - 0.074 12.4 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 OAJ16995.1 - 0.1 12.3 0.0 0.59 9.8 0.0 2.0 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 OAJ16995.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TRAM_LAG1_CLN8 PF03798.16 OAJ16996.1 - 8.1e-41 139.9 21.0 1.1e-40 139.5 21.0 1.2 1 0 0 1 1 1 1 TLC domain DUF4834 PF16118.5 OAJ16996.1 - 0.033 15.1 0.2 3 8.8 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) US10 PF17617.2 OAJ16996.1 - 0.092 12.8 1.0 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 Viral unique short region 10 TRAM1 PF08390.11 OAJ16996.1 - 0.33 10.6 2.1 0.5 10.1 0.1 2.3 2 0 0 2 2 2 0 TRAM1-like protein F_actin_cap_B PF01115.17 OAJ16997.1 - 4.2e-79 265.5 0.0 4.9e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF829 PF05705.14 OAJ16997.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Actin PF00022.19 OAJ16998.1 - 4.8e-112 374.6 0.0 3.9e-111 371.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ16998.1 - 0.092 11.5 0.0 0.85 8.4 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Scm3 PF10384.9 OAJ16999.1 - 2.3e-06 27.2 2.4 4e-06 26.5 0.8 2.3 2 0 0 2 2 2 1 Centromere protein Scm3 Band_7 PF01145.25 OAJ17000.1 - 4.3e-21 75.7 0.7 4.3e-21 75.7 0.7 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family GATase_4 PF13230.6 OAJ17001.1 - 4.5e-17 61.8 0.0 2.3e-16 59.5 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAJ17001.1 - 2.8e-09 37.3 0.0 6.7e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain dCMP_cyt_deam_1 PF00383.23 OAJ17002.1 - 9.3e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ17002.1 - 0.00029 20.6 0.0 0.00076 19.2 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase 2OG-FeII_Oxy_2 PF13532.6 OAJ17004.1 - 9.9e-25 87.9 0.0 1.4e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily An_peroxidase PF03098.15 OAJ17005.1 - 3e-31 108.6 0.1 2.1e-21 76.1 0.1 4.6 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAJ17005.1 - 4.4e-13 48.8 0.0 4.9e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 RINGv PF12906.7 OAJ17006.1 - 7.9e-15 54.7 11.3 1.6e-14 53.7 11.3 1.6 1 0 0 1 1 1 1 RING-variant domain DUF2256 PF10013.9 OAJ17006.1 - 0.063 13.4 0.2 0.063 13.4 0.2 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-RING_2 PF13639.6 OAJ17006.1 - 0.31 11.4 11.2 0.58 10.5 11.2 1.5 1 0 0 1 1 1 0 Ring finger domain Lebercilin PF15619.6 OAJ17006.1 - 0.51 10.0 13.1 0.84 9.3 13.1 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Rootletin PF15035.6 OAJ17006.1 - 1 9.3 12.1 1.8 8.5 12.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion FANCL_C PF11793.8 OAJ17006.1 - 2 8.6 6.7 5 7.4 6.7 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain DivIC PF04977.15 OAJ17006.1 - 7 6.5 10.5 11 5.9 0.3 3.5 3 0 0 3 3 3 0 Septum formation initiator Bax1-I PF01027.20 OAJ17008.1 - 2.8e-33 115.5 6.1 5.2e-33 114.6 6.1 1.5 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cript PF10235.9 OAJ17009.1 - 5.5e-27 94.2 6.6 5.5e-27 94.2 6.6 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 OAJ17009.1 - 0.015 15.7 7.7 0.015 15.7 7.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) C6_DPF PF10170.9 OAJ17009.1 - 0.13 12.6 10.0 2.2 8.7 10.0 2.3 1 1 0 1 1 1 0 Cysteine-rich domain zinc_ribbon_2 PF13240.6 OAJ17009.1 - 0.38 10.5 11.5 0.29 10.9 2.5 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Ccdc124 PF06244.12 OAJ17010.1 - 5.2e-24 85.2 27.8 1.2e-22 80.8 27.8 2.5 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HTH_WhiA PF02650.14 OAJ17010.1 - 0.11 12.9 5.6 7.2 7.0 0.0 2.7 2 1 0 2 2 2 0 WhiA C-terminal HTH domain RNase_T PF00929.24 OAJ17022.1 - 2.5e-16 60.7 0.0 3.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAJ17022.1 - 0.0026 17.5 0.0 0.011 15.5 0.0 2.0 2 1 0 2 2 2 1 3'-5' exonuclease Coq4 PF05019.13 OAJ17023.1 - 1.8e-83 279.3 0.0 2.3e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ATP-synt_ab PF00006.25 OAJ17024.1 - 1.2e-106 355.1 0.0 2e-106 354.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OAJ17024.1 - 5.8e-44 148.8 0.1 1e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OAJ17024.1 - 3.5e-14 53.1 3.1 1e-13 51.6 3.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATG16 PF08614.11 OAJ17025.1 - 3.9e-45 154.6 25.0 4.5e-45 154.3 25.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 OAJ17025.1 - 0.02 15.1 6.4 0.02 15.1 6.4 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3325 PF11804.8 OAJ17025.1 - 0.029 14.5 0.6 0.051 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) FGGY_C PF02782.16 OAJ17025.1 - 0.1 12.3 1.6 0.11 12.2 0.4 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF2388 PF09498.10 OAJ17025.1 - 0.15 12.0 4.2 7.3 6.6 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2388) FlaC_arch PF05377.11 OAJ17025.1 - 0.21 12.0 5.3 5.9 7.4 0.6 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 OAJ17025.1 - 0.3 9.0 2.7 0.42 8.5 2.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlgN PF05130.12 OAJ17025.1 - 0.41 11.2 16.6 0.27 11.7 7.4 2.4 1 1 1 2 2 2 0 FlgN protein AAA_27 PF13514.6 OAJ17025.1 - 0.52 9.9 6.2 1.3 8.6 0.6 2.5 1 1 1 2 2 2 0 AAA domain SHE3 PF17078.5 OAJ17025.1 - 0.75 9.5 15.4 0.093 12.4 11.3 1.5 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Atg14 PF10186.9 OAJ17025.1 - 1.2 8.1 16.1 0.052 12.6 10.1 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YtxH PF12732.7 OAJ17025.1 - 1.3 9.6 6.1 1.9e+02 2.7 6.1 2.9 1 1 0 1 1 1 0 YtxH-like protein SOGA PF11365.8 OAJ17025.1 - 1.3 10.2 14.0 5.9 8.1 0.2 3.1 2 1 2 4 4 4 0 Protein SOGA OmpH PF03938.14 OAJ17025.1 - 1.4 9.2 18.0 0.16 12.3 7.0 2.9 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) YabA PF06156.13 OAJ17025.1 - 1.5 9.5 18.3 2.4 8.9 2.6 3.1 2 1 1 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 OAJ17025.1 - 2.3 8.8 25.0 4.1e+03 -1.8 25.0 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 OAJ17025.1 - 5.7 5.4 5.7 7.4 5.1 5.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A FAM76 PF16046.5 OAJ17025.1 - 9.9 5.4 9.5 35 3.6 9.5 1.9 1 1 0 1 1 1 0 FAM76 protein Aldedh PF00171.22 OAJ17026.1 - 2.6e-24 85.6 0.0 2.9e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PET117 PF15786.5 OAJ17027.1 - 2.1e-19 69.6 0.2 5e-19 68.3 0.2 1.6 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HHV-1_VABD PF16852.5 OAJ17027.1 - 0.083 12.9 0.9 0.083 12.9 0.9 1.7 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain dCMP_cyt_deam_1 PF00383.23 OAJ17028.1 - 1.1e-05 25.2 6.1 0.2 11.5 4.7 3.6 3 1 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region Aldedh PF00171.22 OAJ17030.1 - 1.6e-126 422.6 0.5 1.8e-126 422.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 OAJ17031.1 - 1.9e-30 104.5 0.0 2.9e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 OAJ17031.1 - 0.00031 20.7 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_3 PF08777.11 OAJ17031.1 - 0.00061 19.8 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif NAP PF00956.18 OAJ17033.1 - 1.3e-19 70.5 7.6 5.9e-18 65.0 5.4 2.8 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 OAJ17033.1 - 0.0039 17.4 2.4 0.0039 17.4 2.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) TFIIF_beta_N PF17683.1 OAJ17033.1 - 0.089 13.5 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus Voldacs PF03517.13 OAJ17033.1 - 0.24 11.5 4.1 0.44 10.7 4.1 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling EPO_TPO PF00758.18 OAJ17034.1 - 2.9 7.9 5.4 2.3 8.2 2.5 2.1 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin HAD_2 PF13419.6 OAJ17035.1 - 3.4e-10 40.3 0.0 7.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ17035.1 - 5e-08 33.5 0.0 1.8e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ17035.1 - 0.0051 16.8 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Glyco_hydro_18 PF00704.28 OAJ17036.1 - 2.8e-54 185.0 0.1 3.3e-54 184.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SAM_2 PF07647.17 OAJ17037.1 - 4.8e-13 49.0 0.2 2.2e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 OAJ17037.1 - 5.3e-12 45.2 0.3 1.8e-06 27.5 0.1 3.3 3 0 0 3 3 3 2 SH3 domain SAM_1 PF00536.30 OAJ17037.1 - 6.9e-12 45.6 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 OAJ17037.1 - 7.9e-11 42.5 0.0 1.8e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.6 OAJ17037.1 - 3.2e-05 23.7 5.6 0.006 16.4 0.2 3.2 4 0 0 4 4 4 2 Variant SH3 domain SCO1-SenC PF02630.14 OAJ17038.1 - 8e-42 142.3 0.0 1.5e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAJ17038.1 - 0.016 15.1 0.0 0.059 13.3 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family Ras PF00071.22 OAJ17039.1 - 3.6e-57 192.5 0.1 4.2e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17039.1 - 6.1e-32 110.4 0.0 9.4e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17039.1 - 4.4e-14 52.3 0.0 5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ17039.1 - 6.5e-08 32.7 0.0 1.2e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ17039.1 - 1.3e-06 28.1 0.1 4.4e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ17039.1 - 5.5e-06 25.9 0.1 7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAJ17039.1 - 4.5e-05 23.4 0.2 0.0042 17.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 OAJ17039.1 - 0.00041 20.2 0.5 0.016 15.0 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAJ17039.1 - 0.0013 18.5 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAJ17039.1 - 0.0049 16.2 0.2 0.076 12.3 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 OAJ17039.1 - 0.0063 16.1 0.0 0.024 14.2 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAJ17039.1 - 0.0084 16.5 0.1 0.019 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ17039.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ17039.1 - 0.016 15.0 0.0 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OAJ17039.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAJ17039.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAJ17039.1 - 0.036 14.1 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OAJ17039.1 - 0.051 13.5 0.3 0.099 12.5 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 OAJ17039.1 - 0.056 13.7 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 OAJ17039.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OAJ17039.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 OAJ17039.1 - 0.15 11.2 0.2 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TMEM223 PF14640.6 OAJ17040.1 - 0.00082 19.6 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 2 Transmembrane protein 223 HECT_2 PF09814.9 OAJ17040.1 - 0.048 12.5 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding OHCU_decarbox PF09349.10 OAJ17041.1 - 5.7e-23 82.1 0.0 1.2e-22 81.1 0.0 1.5 1 0 0 1 1 1 1 OHCU decarboxylase MutS_V PF00488.21 OAJ17042.1 - 6.7e-52 176.3 0.0 1.1e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ17042.1 - 1.8e-29 103.3 7.3 1.8e-29 103.3 7.3 2.6 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAJ17042.1 - 0.00058 20.2 0.4 0.00058 20.2 0.4 2.6 2 1 0 2 2 2 1 MutS family domain IV AAA_29 PF13555.6 OAJ17042.1 - 0.037 13.8 0.9 0.099 12.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAJ17042.1 - 0.18 11.4 3.7 0.24 10.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OAJ17042.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain TFIIE_beta PF02186.15 OAJ17043.1 - 7.6e-08 32.5 0.0 8.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 OAJ17044.1 - 2.4e-09 36.7 0.1 3.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 Beta-APP PF03494.13 OAJ17045.1 - 0.062 13.1 0.6 1 9.3 0.6 2.4 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) GATA PF00320.27 OAJ17046.1 - 5.9e-14 51.4 7.3 1.3e-13 50.2 7.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAJ17046.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold Auxin_canalis PF05703.11 OAJ17046.1 - 0.0059 16.6 2.5 0.0059 16.6 2.5 4.8 4 1 0 4 4 4 2 Auxin canalisation FAM76 PF16046.5 OAJ17046.1 - 0.029 13.7 1.3 0.065 12.6 1.3 1.5 1 0 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 OAJ17047.1 - 1.2e-08 35.0 5.6 1.9e-06 27.9 2.6 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAJ17047.1 - 4.4e-07 29.9 4.2 1e-06 28.7 4.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper RAC_head PF16717.5 OAJ17047.1 - 0.0045 17.9 2.6 0.011 16.7 2.6 1.6 1 0 0 1 1 1 1 Ribosome-associated complex head domain PI3K_1B_p101 PF10486.9 OAJ17047.1 - 0.092 10.5 9.3 0.19 9.5 9.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CDC45 PF02724.14 OAJ17047.1 - 0.5 8.6 8.8 1.1 7.5 8.8 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ17047.1 - 9.7 5.4 9.8 16 4.7 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein Beta_elim_lyase PF01212.21 OAJ17048.1 - 3.9e-60 203.6 0.0 5.1e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 OAJ17048.1 - 0.0018 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 OAJ17048.1 - 0.049 12.8 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II Kinesin PF00225.23 OAJ17062.1 - 5.1e-93 311.6 0.0 7.5e-93 311.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ17062.1 - 1.4e-21 77.0 0.0 3.3e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 OAJ17062.1 - 0.38 10.6 6.0 4.3 7.3 0.5 3.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlgN PF05130.12 OAJ17062.1 - 2.4 8.7 5.7 25 5.3 0.8 2.5 2 0 0 2 2 2 0 FlgN protein Uso1_p115_C PF04871.13 OAJ17062.1 - 7.1 7.0 12.6 0.57 10.6 6.4 2.3 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ApoLp-III PF07464.11 OAJ17063.1 - 0.0068 16.5 1.0 0.0068 16.5 1.0 7.4 4 1 3 8 8 8 3 Apolipophorin-III precursor (apoLp-III) HECT PF00632.25 OAJ17064.1 - 3.7e-72 243.4 0.0 5.3e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Crust_neuro_H PF03858.13 OAJ17064.1 - 0.042 14.7 0.1 0.21 12.4 0.1 2.3 1 0 0 1 1 1 0 Crustacean neurohormone H Arm PF00514.23 OAJ17064.1 - 0.56 10.3 5.0 8.2 6.6 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Fungal_trans PF04082.18 OAJ17065.1 - 7.8e-10 38.2 0.0 1.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17065.1 - 1e-06 28.7 9.5 1.7e-06 28.1 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ17066.1 - 1.5e-10 40.6 0.5 2.5e-10 39.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17066.1 - 2.6e-07 30.6 11.2 4.5e-07 29.9 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Forkhead_N PF08430.12 OAJ17066.1 - 0.15 12.7 12.7 0.37 11.4 12.7 1.6 1 0 0 1 1 1 0 Forkhead N-terminal region DER1 PF04511.15 OAJ17067.1 - 7.7e-06 26.0 5.1 1.6e-05 24.9 2.2 2.0 2 0 0 2 2 2 1 Der1-like family Rhomboid PF01694.22 OAJ17067.1 - 8.9e-06 25.8 1.9 1.5e-05 25.0 1.9 1.5 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAJ17067.1 - 2.1e-05 25.0 1.1 3.9e-05 24.2 1.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) FoP_duplication PF13865.6 OAJ17068.1 - 1.8 9.2 8.5 3.9 8.1 8.5 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF3328 PF11807.8 OAJ17069.1 - 0.046 13.5 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) rRNA_proc-arch PF13234.6 OAJ17070.1 - 3.3e-72 243.7 0.2 5.7e-72 242.9 0.2 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 OAJ17070.1 - 1.2e-50 171.3 1.9 1.2e-50 171.3 1.9 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 OAJ17070.1 - 1.8e-19 70.2 0.0 6.1e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ17070.1 - 8.8e-07 29.2 0.0 6.1e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ17070.1 - 0.0036 17.3 0.0 0.0094 16.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 OAJ17070.1 - 0.056 12.8 0.3 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 OAJ17070.1 - 0.072 13.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 OAJ17070.1 - 0.11 12.4 0.4 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Transket_pyr PF02779.24 OAJ17071.1 - 7.4e-37 126.7 0.0 1.2e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ17071.1 - 2.6e-26 91.9 0.0 9.4e-26 90.1 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_L10 PF00466.20 OAJ17071.1 - 0.0033 17.5 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S49_N PF08496.10 OAJ17073.1 - 0.78 9.8 3.5 1.1 9.3 3.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.25 OAJ17074.1 - 1.6e-57 194.8 0.0 5.4e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17074.1 - 3.2e-19 69.2 0.0 7.4e-16 58.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SDA1 PF05285.12 OAJ17074.1 - 0.00024 20.7 9.4 0.00036 20.1 9.4 1.3 1 0 0 1 1 1 1 SDA1 Kdo PF06293.14 OAJ17074.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ17074.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CDC45 PF02724.14 OAJ17074.1 - 0.24 9.7 10.1 0.5 8.6 10.1 1.5 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 OAJ17074.1 - 0.26 11.2 5.0 0.26 11.2 0.2 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PI3K_1B_p101 PF10486.9 OAJ17074.1 - 0.41 8.4 6.5 0.67 7.7 6.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 OAJ17074.1 - 0.6 9.4 15.9 1.2 8.4 15.9 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIF_alpha PF05793.12 OAJ17074.1 - 0.72 8.4 16.0 1.1 7.7 16.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GREB1 PF15782.5 OAJ17074.1 - 8 3.4 8.3 12 2.9 8.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BUD22 PF09073.10 OAJ17074.1 - 8.6 5.6 28.4 16 4.7 24.5 2.3 2 0 0 2 2 2 0 BUD22 PH_12 PF16457.5 OAJ17075.1 - 7.2e-32 110.7 0.0 1.4e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 OAJ17075.1 - 2e-26 93.1 0.0 3.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 OAJ17075.1 - 4.4e-23 81.9 0.0 1.6e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.16 OAJ17075.1 - 0.0061 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain V-ATPase_H_N PF03224.14 OAJ17075.1 - 0.024 14.0 0.0 0.054 12.8 0.0 1.5 2 0 0 2 2 2 0 V-ATPase subunit H PHF5 PF03660.14 OAJ17076.1 - 5.8e-46 155.0 8.2 6.2e-46 154.9 8.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAJ17076.1 - 0.025 12.5 4.6 0.025 12.5 4.6 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_2 PF03107.16 OAJ17076.1 - 0.064 13.6 1.7 0.064 13.6 1.7 2.7 2 1 0 2 2 2 0 C1 domain DZR PF12773.7 OAJ17076.1 - 1.7 8.7 14.9 1 9.4 1.6 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.18 OAJ17095.1 - 2.6e-11 42.6 12.1 1.2e-06 27.7 1.0 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others NST1 PF13945.6 OAJ17096.1 - 3.1e-48 164.4 0.0 3.1e-48 164.4 0.0 8.1 6 2 1 7 7 7 2 Salt tolerance down-regulator LTV PF04180.14 OAJ17096.1 - 0.00016 21.6 1.8 0.00016 21.6 1.8 6.3 4 1 1 5 5 5 1 Low temperature viability protein GTP_EFTU PF00009.27 OAJ17097.1 - 1e-26 93.7 0.4 1.7e-20 73.4 2.3 3.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAJ17097.1 - 4.9e-22 78.0 0.1 9.7e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAJ17097.1 - 5e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAJ17097.1 - 0.042 14.2 0.6 4.7 7.7 0.0 3.0 2 0 0 2 2 2 0 Elongation factor Tu domain 2 SRPRB PF09439.10 OAJ17097.1 - 0.048 13.1 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Nsp1_C PF05064.13 OAJ17099.1 - 1.9e-21 76.0 0.0 8.6e-21 73.9 0.0 1.9 2 0 0 2 2 2 1 Nsp1-like C-terminal region Baculo_PEP_C PF04513.12 OAJ17099.1 - 1.2 9.2 3.6 19 5.3 0.7 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HLH PF00010.26 OAJ17100.1 - 4.3e-13 49.0 0.0 9.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sec1 PF00995.23 OAJ17101.1 - 5.2e-128 428.8 0.0 6.6e-128 428.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family YxiJ PF14176.6 OAJ17101.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 YxiJ-like protein zf-primase PF09329.11 OAJ17102.1 - 3.5e-12 45.9 1.9 6.5e-12 45.1 1.9 1.5 1 0 0 1 1 1 1 Primase zinc finger PHD PF00628.29 OAJ17106.1 - 3.9e-05 23.4 11.8 3.9e-05 23.4 11.8 2.3 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 OAJ17106.1 - 2.5 8.4 11.9 2.5 8.4 5.6 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain RhoGEF PF00621.20 OAJ17107.1 - 1e-34 120.4 0.3 1.5e-34 119.8 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 OAJ17107.1 - 6.5e-31 107.1 0.0 1.2e-30 106.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OAJ17107.1 - 5.8e-21 74.5 0.0 2.4e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.24 OAJ17107.1 - 7.8e-10 38.6 0.1 1.4e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 OAJ17107.1 - 0.00073 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Glyco_hydro_25 PF01183.20 OAJ17108.1 - 1.5e-47 162.0 4.6 1.8e-47 161.8 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RNA_pol PF00940.19 OAJ17109.1 - 1.3e-170 567.8 0.0 1.7e-170 567.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAJ17109.1 - 4.2e-83 279.5 0.0 4.2e-83 279.5 0.0 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal GST_C PF00043.25 OAJ17110.1 - 6.2e-13 48.8 0.5 1e-12 48.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 OAJ17110.1 - 1.5e-10 41.2 0.3 5.7e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ17110.1 - 4.7e-09 36.1 0.0 7.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ17110.1 - 7.2e-09 35.7 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ17110.1 - 0.00027 21.3 0.0 0.00064 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAJ17110.1 - 0.00078 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ISAV_HA PF06215.11 OAJ17110.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin Ribosomal_60s PF00428.19 OAJ17110.1 - 0.36 11.4 8.0 0.9 10.2 8.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 OAJ17110.1 - 2.7 8.7 6.0 5.3 7.7 6.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CPDase PF07823.11 OAJ17111.1 - 4.4e-21 75.5 0.0 8e-21 74.6 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAJ17111.1 - 1.2e-07 31.7 0.1 1.7e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily HemN_C PF06969.16 OAJ17111.1 - 0.036 14.1 0.3 0.19 11.8 0.3 2.1 1 1 0 1 1 1 0 HemN C-terminal domain LigT_PEase PF02834.16 OAJ17111.1 - 0.088 13.0 0.3 0.44 10.8 0.1 2.2 2 1 0 2 2 2 0 LigT like Phosphoesterase DUF2250 PF10007.9 OAJ17111.1 - 0.11 12.6 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) CTP_transf_like PF01467.26 OAJ17128.1 - 2.6e-22 79.5 0.0 4.6e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like CDC45 PF02724.14 OAJ17128.1 - 0.32 9.2 14.0 0.45 8.7 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAJ17128.1 - 0.87 8.1 5.7 1.2 7.6 5.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAJ17128.1 - 1.9 6.6 16.0 3.2 5.8 16.0 1.3 1 0 0 1 1 1 0 Nop14-like family CNOT11 PF10155.9 OAJ17129.1 - 0.0029 17.8 0.0 12 6.0 0.0 3.3 3 0 0 3 3 3 3 CCR4-NOT transcription complex subunit 11 RRM_1 PF00076.22 OAJ17130.1 - 9.3e-32 108.7 0.1 1.8e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ17130.1 - 3.5e-12 46.3 0.1 5.5e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ17130.1 - 0.00065 19.7 0.1 0.87 9.6 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Mpt_N PF09176.11 OAJ17130.1 - 0.013 15.6 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal RRM_3 PF08777.11 OAJ17130.1 - 0.029 14.4 0.0 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Tyrosinase PF00264.20 OAJ17131.1 - 9.8e-46 156.8 4.4 1.5e-45 156.2 4.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase PPO1_DWL PF12142.8 OAJ17131.1 - 0.029 14.1 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain DiS_P_DiS PF06750.13 OAJ17131.1 - 0.094 12.9 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PASTA PF03793.19 OAJ17131.1 - 0.15 11.9 0.3 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 PASTA domain Mito_carr PF00153.27 OAJ17133.1 - 7.5e-58 192.5 2.6 1.1e-20 73.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAJ17134.1 - 8.4e-50 168.5 0.0 1.3e-49 168.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17134.1 - 6.6e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17134.1 - 2e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ17134.1 - 0.044 13.3 0.0 0.096 12.2 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAJ17134.1 - 0.077 13.4 0.2 0.23 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OAJ17134.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit UPF0020 PF01170.18 OAJ17135.1 - 2.5e-09 37.1 0.0 9.2e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OAJ17135.1 - 5.6e-05 23.0 0.0 0.00067 19.4 0.0 2.5 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 OAJ17135.1 - 0.0045 16.3 0.0 0.018 14.3 0.0 1.8 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 OAJ17135.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF3506 PF12014.8 OAJ17136.1 - 5.4e-11 42.7 0.0 2.9e-10 40.3 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 OAJ17136.1 - 2.1e-07 30.7 0.1 5e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ17136.1 - 5.1e-05 23.0 0.1 0.00014 21.6 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAJ17136.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 F-box Peptidase_M76 PF09768.9 OAJ17137.1 - 3e-50 170.3 0.0 4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAJ17137.1 - 0.043 13.7 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 SprT-like family Aldo_ket_red PF00248.21 OAJ17138.1 - 3.8e-72 243.0 0.0 4.3e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 OAJ17139.1 - 1.3e-09 38.0 0.0 1.4e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ17139.1 - 0.00011 22.2 0.0 0.00012 22.0 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding APG5 PF04106.12 OAJ17140.1 - 1.9e-63 214.1 0.0 2.5e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1168 PF06658.12 OAJ17140.1 - 8.9 6.1 6.0 8.6 6.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) COPIIcoated_ERV PF07970.12 OAJ17141.1 - 1.7e-37 129.4 0.3 2.6e-37 128.8 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ17141.1 - 1.2e-24 86.5 0.0 2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Fungal_trans PF04082.18 OAJ17142.1 - 2.1e-13 49.9 0.6 4.5e-13 48.8 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17142.1 - 1.5e-07 31.4 10.2 2.3e-07 30.8 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ17142.1 - 0.002 18.2 11.9 0.002 18.2 11.9 5.0 2 2 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 OAJ17142.1 - 7.7 6.7 37.9 6.2 7.0 0.3 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 ALO PF04030.14 OAJ17144.1 - 7.8e-61 206.2 0.1 5.1e-51 174.0 0.1 2.4 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAJ17144.1 - 2.6e-19 69.3 0.0 4.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S17 PF00366.20 OAJ17145.1 - 1.6e-20 72.9 0.2 3e-20 72.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 VCX_VCY PF15231.6 OAJ17145.1 - 0.071 13.8 8.2 0.13 13.0 8.2 1.4 1 0 0 1 1 1 0 Variable charge X/Y family UBA_4 PF14555.6 OAJ17146.1 - 5.9e-10 38.8 0.1 1.5e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain HBM PF16591.5 OAJ17146.1 - 0.063 12.7 0.2 0.46 9.9 0.2 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain UIM PF02809.20 OAJ17146.1 - 0.24 11.4 9.4 3.6 7.7 0.8 3.1 2 0 0 2 2 2 0 Ubiquitin interaction motif SR-25 PF10500.9 OAJ17161.1 - 4.3 6.9 9.9 6.5 6.3 9.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Polysacc_deac_1 PF01522.21 OAJ17162.1 - 5.5e-19 68.3 0.0 1.2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SR-25 PF10500.9 OAJ17162.1 - 2.8 7.5 7.3 4.1 6.9 7.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.8 OAJ17162.1 - 7.2 5.6 7.6 11 5.0 7.6 1.2 1 0 0 1 1 1 0 SprA-related family FA_hydroxylase PF04116.13 OAJ17163.1 - 2.8e-21 76.2 2.2 2.8e-21 76.2 2.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NUSAP PF16006.5 OAJ17164.1 - 0.0089 15.8 2.8 0.0093 15.8 2.8 1.2 1 0 0 1 1 1 1 Nucleolar and spindle-associated protein Ras PF00071.22 OAJ17165.1 - 1e-53 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17165.1 - 4e-19 69.0 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17165.1 - 1.9e-06 27.4 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ17165.1 - 0.14 11.7 0.1 1.2 8.6 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain OPT PF03169.15 OAJ17166.1 - 1.8e-93 314.3 42.8 2e-93 314.1 42.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 OAJ17167.1 - 6.6e-62 209.3 0.0 8.4e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17167.1 - 2.8e-43 148.1 0.0 3.8e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ17167.1 - 3.1e-06 26.7 0.0 7e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ17167.1 - 9e-06 24.7 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ17167.1 - 2.4e-05 24.4 0.2 0.075 13.0 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ17167.1 - 0.053 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 OAJ17168.1 - 5.2e-05 22.6 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ17168.1 - 0.00016 21.2 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain F-box-like PF12937.7 OAJ17170.1 - 2.4e-05 24.2 0.1 8.8e-05 22.3 0.1 2.1 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OAJ17171.1 - 3.4e-11 43.5 2.5 0.15 13.0 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17171.1 - 1.3e-07 31.8 0.0 0.00014 22.0 0.0 2.9 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TolA_bind_tri PF16331.5 OAJ17171.1 - 0.048 13.7 1.1 0.092 12.8 1.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Nup160 PF11715.8 OAJ17171.1 - 0.17 10.5 0.1 0.38 9.3 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 THUMP PF02926.17 OAJ17172.1 - 1.9e-14 54.0 0.1 4.5e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 THUMP domain Thioesterase PF00975.20 OAJ17173.1 - 1.1e-15 58.4 0.0 1.9e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 OAJ17173.1 - 0.00019 21.2 0.0 0.0004 20.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17173.1 - 0.00044 20.9 0.1 0.0013 19.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ17173.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 OAJ17175.1 - 2e-82 277.0 0.0 3.2e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 OAJ17175.1 - 1.7e-67 227.7 1.0 1.3e-66 224.8 0.1 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 OAJ17175.1 - 1.1e-63 215.5 0.0 1.8e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.21 OAJ17175.1 - 9.8e-59 199.4 0.0 2.7e-58 198.0 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 OAJ17175.1 - 1.8e-54 184.4 4.4 2.3e-54 184.1 0.2 3.5 4 1 0 4 4 4 1 KR domain NAD_binding_4 PF07993.12 OAJ17175.1 - 3.9e-33 114.7 0.0 1.4e-32 112.9 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 OAJ17175.1 - 8.1e-32 109.7 0.1 2e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 OAJ17175.1 - 1.7e-22 79.5 1.7 3.2e-12 46.6 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 OAJ17175.1 - 2.4e-18 66.6 0.0 7.2e-17 61.9 0.0 3.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 OAJ17175.1 - 3.9e-08 32.9 0.2 7.3e-08 32.0 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.25 OAJ17175.1 - 3.8e-07 29.8 0.0 3.8e-07 29.8 0.0 3.3 4 0 0 4 4 4 1 short chain dehydrogenase AMP-binding_C PF13193.6 OAJ17175.1 - 0.0012 19.8 0.1 0.01 16.8 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OAJ17175.1 - 0.033 13.2 0.0 0.17 10.9 0.0 2.2 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family SAT PF16073.5 OAJ17175.1 - 0.063 13.0 0.1 0.91 9.2 0.1 2.4 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Epimerase PF01370.21 OAJ17175.1 - 0.15 11.5 0.1 1.1 8.6 0.0 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 OAJ17177.1 - 1.6e-42 145.7 52.6 1.6e-42 145.7 52.6 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ17177.1 - 3.9e-21 75.1 14.6 3.9e-21 75.1 14.6 1.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ17177.1 - 2.4e-08 33.3 15.8 2.4e-08 33.3 15.8 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAJ17177.1 - 0.0046 15.3 1.2 0.0046 15.3 1.2 3.1 4 0 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpb1_5 PF04998.17 OAJ17189.1 - 4.2e-87 292.0 0.0 9e-87 290.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ17189.1 - 3.4e-64 216.1 0.1 6.6e-64 215.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ17189.1 - 1.5e-34 119.2 0.0 3.1e-34 118.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAJ17189.1 - 4.5e-30 105.1 0.2 1e-23 84.2 0.0 4.3 5 1 0 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAJ17189.1 - 1.9e-21 76.0 2.2 2.6e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 BUD22 PF09073.10 OAJ17189.1 - 0.074 12.4 33.0 0.2 11.0 23.2 2.2 2 0 0 2 2 2 0 BUD22 DUF2205 PF10224.9 OAJ17189.1 - 0.098 12.7 0.1 0.77 9.8 0.0 2.4 2 0 0 2 2 2 0 Short coiled-coil protein Ist1 PF03398.14 OAJ17189.1 - 0.1 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Il13Ra_Ig PF18001.1 OAJ17189.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain CCDC106 PF15794.5 OAJ17189.1 - 0.28 10.8 21.8 0.09 12.5 5.5 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 DUF913 PF06025.12 OAJ17189.1 - 1.1 8.1 7.3 5.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Raptor_N PF14538.6 OAJ17192.1 - 1.6e-51 174.1 0.0 3.7e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OAJ17192.1 - 4.8e-06 27.2 7.7 1.2 10.2 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 OAJ17192.1 - 0.0075 16.4 5.7 0.53 10.7 0.0 5.4 6 0 0 6 6 6 1 HEAT repeat DUF1508 PF07411.12 OAJ17192.1 - 0.089 12.7 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Spt20 PF12090.8 OAJ17192.1 - 0.14 11.7 12.4 0.29 10.7 12.4 1.4 1 0 0 1 1 1 0 Spt20 family PGA2 PF07543.12 OAJ17192.1 - 0.15 12.0 2.2 0.31 11.0 2.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Slu7 PF11708.8 OAJ17192.1 - 0.96 9.1 5.2 1.6 8.4 5.2 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Acetyltransf_1 PF00583.25 OAJ17193.1 - 7.1e-13 48.8 0.0 9.1e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ17193.1 - 4.9e-08 33.3 0.0 7.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ17193.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ17193.1 - 0.00033 20.6 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAJ17193.1 - 0.0011 19.0 0.0 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 OAJ17193.1 - 0.0026 18.5 0.0 0.0033 18.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ17193.1 - 0.0044 17.1 0.0 0.022 14.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAJ17193.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PNRC PF15365.6 OAJ17194.1 - 1.1e-08 34.7 2.0 1.1e-08 34.7 2.0 4.1 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif CobT PF06213.12 OAJ17194.1 - 8.7 5.6 17.0 16 4.8 17.0 1.6 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT PCI PF01399.27 OAJ17195.1 - 1.3e-16 60.9 0.2 3.7e-16 59.5 0.2 1.7 1 0 0 1 1 1 1 PCI domain FmiP_Thoc5 PF09766.9 OAJ17195.1 - 0.0021 17.4 0.4 0.0033 16.8 0.4 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 TPR_14 PF13428.6 OAJ17195.1 - 0.037 14.8 0.5 25 6.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3116 PF11313.8 OAJ17195.1 - 0.043 13.7 5.7 0.31 10.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3116) FeoC PF09012.10 OAJ17195.1 - 0.079 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_2 PF07719.17 OAJ17195.1 - 0.85 9.9 5.4 16 6.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 OAJ17196.1 - 2.8e-10 40.3 0.1 7.7e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ17196.1 - 0.0026 18.1 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal JmjC PF02373.22 OAJ17197.1 - 5.8e-09 36.4 0.0 9.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase CLASP_N PF12348.8 OAJ17198.1 - 1.7e-64 217.5 1.7 2.7e-52 177.6 0.1 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 OAJ17198.1 - 4.6e-05 23.3 7.2 0.23 11.8 0.1 5.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 OAJ17198.1 - 0.038 14.0 0.1 2.7 8.0 0.0 3.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAJ17198.1 - 0.047 13.6 0.0 0.25 11.3 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 OAJ17198.1 - 0.42 11.0 18.0 6.4 7.2 0.4 5.7 5 1 1 6 6 6 0 HEAT repeats DUF775 PF05603.12 OAJ17199.1 - 1.9e-43 148.3 0.0 2.2e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Gln-synt_C PF00120.24 OAJ17200.1 - 1.4e-15 57.1 0.0 2.7e-12 46.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAJ17200.1 - 1.4e-12 47.1 0.0 2.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RRM_1 PF00076.22 OAJ17201.1 - 4.7e-11 42.3 0.0 8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1712 PF08217.11 OAJ17202.1 - 0.1 11.1 0.0 0.18 10.2 0.0 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Mob1_phocein PF03637.17 OAJ17203.1 - 4.3e-21 75.7 0.0 6.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.10 OAJ17203.1 - 0.014 15.8 0.1 0.014 15.8 0.1 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Mgm101p PF06420.12 OAJ17204.1 - 2.5e-82 274.4 0.0 3.2e-82 274.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 SPC25 PF06703.11 OAJ17205.1 - 7.3e-33 113.6 0.0 8.7e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short_C2 PF13561.6 OAJ17207.1 - 2.4e-50 171.3 0.0 4.3e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Rit1_C PF17184.4 OAJ17207.1 - 7.7e-49 166.6 0.0 2.9e-48 164.7 0.0 1.8 2 0 0 2 2 2 1 Rit1 N-terminal domain adh_short PF00106.25 OAJ17207.1 - 1.5e-41 142.1 0.0 2.2e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Init_tRNA_PT PF04179.12 OAJ17207.1 - 2e-14 53.8 0.0 8.6e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain KR PF08659.10 OAJ17207.1 - 3.5e-12 46.6 0.1 6.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OAJ17207.1 - 0.012 15.0 0.1 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sde2_N_Ubi PF13019.6 OAJ17208.1 - 3.4e-41 140.8 1.7 3.5e-41 140.8 0.1 1.8 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain FAM176 PF14851.6 OAJ17208.1 - 0.21 11.3 2.5 0.36 10.5 2.5 1.5 1 0 0 1 1 1 0 FAM176 family SH3_9 PF14604.6 OAJ17209.1 - 2.4e-28 97.7 4.6 1.9e-13 50.1 0.1 2.6 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 OAJ17209.1 - 1.1e-25 89.0 4.5 4.1e-12 45.5 0.1 2.9 3 0 0 3 3 3 2 SH3 domain Cofilin_ADF PF00241.20 OAJ17209.1 - 7.1e-20 71.0 0.0 1.3e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 OAJ17209.1 - 2.5e-16 59.1 0.0 1.2e-06 28.1 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain Amidase PF01425.21 OAJ17223.1 - 1.6e-80 271.3 0.0 1e-64 219.2 0.3 2.1 2 0 0 2 2 2 2 Amidase Minor_tail_Z PF06763.11 OAJ17223.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) AAA PF00004.29 OAJ17224.1 - 9.9e-44 149.0 0.0 1.8e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ17224.1 - 3.8e-10 39.4 0.1 8.1e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ17224.1 - 2.5e-08 34.2 0.0 5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OAJ17224.1 - 1.3e-07 31.4 0.5 2.9e-07 30.3 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ17224.1 - 2.9e-06 27.3 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ17224.1 - 7.4e-06 26.5 0.1 8.4e-05 23.0 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ17224.1 - 1.1e-05 25.8 0.2 0.0061 16.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ17224.1 - 5.7e-05 22.9 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ17224.1 - 0.001 19.6 0.1 0.022 15.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 OAJ17224.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAJ17224.1 - 0.0014 18.8 0.1 0.0035 17.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 OAJ17224.1 - 0.0027 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 OAJ17224.1 - 0.0045 16.5 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.11 OAJ17224.1 - 0.0055 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAJ17224.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ17224.1 - 0.01 15.5 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ17224.1 - 0.011 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.7 OAJ17224.1 - 0.013 15.1 1.9 0.021 14.4 1.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TsaE PF02367.17 OAJ17224.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAJ17224.1 - 0.019 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 OAJ17224.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 OAJ17224.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ17224.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region APG6_N PF17675.1 OAJ17224.1 - 0.034 14.7 0.1 0.06 13.9 0.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_14 PF13173.6 OAJ17224.1 - 0.037 14.0 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ17224.1 - 0.046 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 OAJ17224.1 - 0.052 13.8 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_25 PF13481.6 OAJ17224.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAJ17224.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 OAJ17224.1 - 0.083 12.7 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RILP PF11461.8 OAJ17224.1 - 0.094 13.0 1.2 0.2 11.9 1.2 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 OAJ17224.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 OAJ17224.1 - 0.17 12.3 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAJ17225.1 - 6.5e-19 68.6 0.0 1.1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ17225.1 - 3.2e-13 49.8 0.0 5.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ17225.1 - 8.1e-12 45.5 0.0 2.2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 OAJ17225.1 - 0.00026 21.4 0.0 0.00095 19.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAJ17225.1 - 0.00057 19.8 3.6 0.29 10.9 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ17225.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAJ17225.1 - 0.0027 16.8 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 OAJ17225.1 - 0.0049 16.6 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 OAJ17225.1 - 0.0052 17.1 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ17225.1 - 0.0069 16.7 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAJ17225.1 - 0.013 16.0 0.4 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ17225.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 OAJ17225.1 - 0.048 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) XhlA PF10779.9 OAJ17225.1 - 0.27 11.5 5.0 0.6 10.4 5.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF3395 PF11875.8 OAJ17225.1 - 1.4 8.8 6.3 3.7 7.4 6.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Pex24p PF06398.11 OAJ17226.1 - 8.5e-31 107.2 0.9 2.2e-29 102.6 0.1 2.2 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Fer2 PF00111.27 OAJ17229.1 - 1e-10 41.4 0.5 1.5e-10 40.8 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CDCA PF18484.1 OAJ17229.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat Abhydrolase_1 PF00561.20 OAJ17230.1 - 4.3e-23 82.3 0.1 5.3e-20 72.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ17230.1 - 8.2e-12 45.2 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DEAD PF00270.29 OAJ17231.1 - 2.9e-19 69.5 0.0 5.7e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ17231.1 - 1.1e-15 58.0 0.1 1.3e-12 48.0 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAJ17231.1 - 8.5e-10 39.2 0.1 2.3e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 OAJ17231.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SgrR_N PF12793.7 OAJ17231.1 - 0.032 14.4 0.1 0.087 13.0 0.1 1.7 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term HisKA PF00512.25 OAJ17231.1 - 4.7 7.3 5.5 4.8 7.3 1.7 2.8 3 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Metallophos PF00149.28 OAJ17232.1 - 2.1e-18 67.6 0.0 5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 OAJ17232.1 - 1.8e-13 51.1 0.0 4.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 OAJ17232.1 - 5.6e-13 49.3 0.3 1.2e-12 48.2 0.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 OAJ17232.1 - 0.00016 21.9 1.1 0.00033 21.0 1.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain PhoD_N PF16655.5 OAJ17232.1 - 0.0024 18.4 0.0 0.0047 17.4 0.0 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain MULE PF10551.9 OAJ17233.1 - 2.6e-07 30.9 0.0 8.1e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ17233.1 - 0.0082 16.8 0.8 0.018 15.7 0.8 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain SPX PF03105.19 OAJ17234.1 - 2.6e-35 123.1 6.8 1.3e-25 91.2 0.2 2.4 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 OAJ17234.1 - 2.3e-32 112.4 58.7 8e-29 100.8 28.8 2.3 2 1 1 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 OAJ17234.1 - 2e-31 109.6 36.2 2.8e-31 109.1 36.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF997 PF06196.12 OAJ17234.1 - 0.5 10.4 8.6 2.9 8.0 0.2 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF997) KGG PF10685.9 OAJ17235.1 - 4e-19 68.2 1.8 3.3e-09 36.7 0.1 2.6 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Aa_trans PF01490.18 OAJ17236.1 - 8.1e-56 189.5 8.1 4.8e-55 186.9 8.1 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ17236.1 - 0.0027 16.8 5.8 0.0027 16.8 5.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family BUD22 PF09073.10 OAJ17236.1 - 0.031 13.6 16.3 0.055 12.8 16.3 1.4 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 OAJ17236.1 - 0.47 10.5 16.0 0.96 9.5 16.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 OAJ17236.1 - 1.3 7.1 13.6 1.9 6.6 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ17236.1 - 2.5 7.4 15.3 4.1 6.7 15.3 1.2 1 0 0 1 1 1 0 SDA1 SNase PF00565.17 OAJ17237.1 - 5.3e-44 149.1 1.9 1.2e-16 61.2 0.0 7.1 6 1 0 6 6 6 4 Staphylococcal nuclease homologue TUDOR PF00567.24 OAJ17237.1 - 5.1e-23 81.4 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 OAJ17237.1 - 4.4e-07 30.3 0.0 4.6e-05 23.8 0.0 3.0 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 OAJ17237.1 - 0.0056 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) SMN PF06003.12 OAJ17237.1 - 0.052 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) WD40 PF00400.32 OAJ17238.1 - 1.5e-38 130.1 21.0 3.3e-09 37.2 0.3 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17238.1 - 1.3e-16 60.7 0.0 3.8e-05 23.9 0.0 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ17238.1 - 0.00073 18.6 0.2 2.6 6.9 0.0 4.1 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 OAJ17238.1 - 0.001 18.7 0.2 11 5.8 0.0 3.8 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PD40 PF07676.12 OAJ17238.1 - 0.0031 17.4 0.3 1.2 9.1 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat NHL PF01436.21 OAJ17238.1 - 0.012 15.6 0.0 3.6 7.8 0.0 3.0 2 0 0 2 2 2 0 NHL repeat eIF2A PF08662.11 OAJ17238.1 - 0.23 11.3 0.0 19 5.1 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Fcf1 PF04900.12 OAJ17239.1 - 1.5e-16 60.6 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Fcf1 mRNA_triPase PF02940.15 OAJ17240.1 - 1.5e-48 165.4 0.0 1.8e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain N2227 PF07942.12 OAJ17241.1 - 3.2e-88 295.5 0.0 4.7e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein PSII_Pbs27 PF13326.6 OAJ17241.1 - 0.0091 16.3 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 Photosystem II Pbs27 DUF3043 PF11241.8 OAJ17241.1 - 3.7 7.5 10.4 0.68 9.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) CPSF_A PF03178.15 OAJ17242.1 - 3.1e-71 240.3 0.1 4.9e-71 239.7 0.1 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ17242.1 - 4.7e-07 28.8 0.0 1e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoporin_N PF08801.11 OAJ17242.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like PseudoU_synth_2 PF00849.22 OAJ17257.1 - 1.4e-26 93.5 0.1 2.2e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Y_phosphatase2 PF03162.13 OAJ17258.1 - 1.1e-50 171.4 0.0 1.3e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ17258.1 - 0.00047 20.2 0.0 0.0018 18.3 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ17258.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MIF4G PF02854.19 OAJ17259.1 - 7.1e-55 185.9 2.5 2.4e-54 184.2 2.5 1.9 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAJ17259.1 - 2.5e-13 50.0 0.0 7.3e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 OAJ17259.1 - 0.0051 16.8 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 MA3 domain Adaptin_binding PF10199.9 OAJ17259.1 - 0.17 12.5 0.0 0.17 12.5 0.0 6.1 4 2 1 5 5 5 0 Alpha and gamma adaptin binding protein p34 Cpn60_TCP1 PF00118.24 OAJ17261.1 - 4.4e-148 494.0 2.4 5e-148 493.8 2.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 OAJ17261.1 - 0.025 14.1 0.2 0.25 10.9 0.1 2.5 3 0 0 3 3 3 0 Propionate catabolism activator Nitro_FeMo-Co PF02579.17 OAJ17261.1 - 0.085 13.2 0.2 0.46 10.8 0.0 2.3 2 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor LRR_9 PF14580.6 OAJ17262.1 - 1.1e-60 204.1 0.0 1.5e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAJ17262.1 - 4.4e-12 46.0 14.1 4.8e-07 30.0 1.3 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ17262.1 - 1.2e-10 40.9 10.9 2e-06 27.4 2.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 OAJ17262.1 - 0.059 13.4 0.2 36 4.8 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat Adaptin_N PF01602.20 OAJ17263.1 - 6.4e-101 338.5 0.0 2e-100 336.9 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ17263.1 - 3.9e-08 33.5 0.0 5.7e-06 26.5 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ17263.1 - 4.5e-05 23.7 13.8 0.0039 17.6 0.1 5.1 4 1 0 4 4 4 2 HEAT repeats Arm PF00514.23 OAJ17263.1 - 0.027 14.5 0.6 25 5.1 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAJ17263.1 - 0.031 14.5 6.5 30 5.2 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat Cnd3 PF12719.7 OAJ17263.1 - 0.13 11.4 0.2 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain PWWP PF00855.17 OAJ17264.1 - 6.2e-21 74.6 0.2 6.2e-21 74.6 0.2 2.6 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 OAJ17264.1 - 3.3e-08 33.4 0.3 3.3e-08 33.4 0.3 2.4 3 0 0 3 3 3 1 TFIIS helical bundle-like domain Codanin-1_C PF15296.6 OAJ17264.1 - 9 6.4 8.9 11 6.1 3.8 2.6 1 1 1 2 2 2 0 Codanin-1 C-terminus Ras PF00071.22 OAJ17265.1 - 1.2e-51 174.6 0.1 1.6e-51 174.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17265.1 - 1.2e-28 99.7 0.0 2.2e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17265.1 - 2.1e-10 40.4 0.0 5.3e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ17265.1 - 1.4e-05 25.2 0.1 3.4e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ17265.1 - 0.0034 17.0 0.0 0.0093 15.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ17265.1 - 0.0037 16.7 0.0 0.0089 15.5 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OAJ17265.1 - 0.031 14.3 0.3 0.11 12.5 0.0 1.9 2 1 0 2 2 2 0 Dynamin family Vps26 PF03643.15 OAJ17267.1 - 3.2e-130 433.1 3.7 3.7e-130 432.9 3.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 OAJ17267.1 - 0.035 14.2 2.6 0.34 11.0 0.1 3.1 3 1 1 4 4 4 0 Arrestin (or S-antigen), N-terminal domain Septin PF00735.18 OAJ17268.1 - 1.4e-122 408.4 0.2 2.6e-122 407.5 0.2 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ17268.1 - 4.8e-08 33.1 0.1 1.5e-07 31.5 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ17268.1 - 6.7e-06 26.1 3.9 4.1e-05 23.6 0.1 2.8 3 1 0 3 3 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ17268.1 - 2.9e-05 23.7 3.2 0.00055 19.5 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 OAJ17268.1 - 0.00034 20.2 0.3 0.004 16.8 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 OAJ17268.1 - 0.002 18.4 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ17268.1 - 0.0021 18.5 0.1 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 OAJ17268.1 - 0.0024 17.2 1.4 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 OAJ17268.1 - 0.004 17.7 7.1 0.79 10.2 7.1 2.6 1 1 0 1 1 1 1 ABC transporter baeRF_family3 PF18845.1 OAJ17268.1 - 0.007 16.6 2.8 0.015 15.6 2.8 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 Dynamin_N PF00350.23 OAJ17268.1 - 0.0071 16.4 6.4 0.082 13.0 0.0 3.4 2 2 1 3 3 3 1 Dynamin family Roc PF08477.13 OAJ17268.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ17268.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAJ17268.1 - 0.036 14.5 0.1 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAJ17268.1 - 0.047 12.9 1.3 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OAJ17268.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 OAJ17268.1 - 0.073 12.8 0.1 3 7.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OAJ17268.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 OAJ17268.1 - 0.32 11.0 2.2 2.4 8.1 0.0 3.0 3 1 2 5 5 5 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 OAJ17268.1 - 0.63 10.5 11.1 63 4.0 11.1 2.2 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 OAJ17268.1 - 0.8 9.2 7.1 1.3 8.5 7.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 OAJ17268.1 - 5.7 7.1 9.5 0.48 10.5 0.6 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 OAJ17268.1 - 6.8 6.4 6.8 24 4.6 0.0 3.4 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.16 OAJ17269.1 - 9e-46 156.4 47.5 3.1e-45 154.6 47.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TFIIA PF03153.13 OAJ17270.1 - 2.1e-49 169.6 11.3 4.5e-29 102.7 8.5 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit TRP PF06011.12 OAJ17271.1 - 1.3e-67 228.5 11.1 1.9e-67 227.9 11.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAJ17271.1 - 8.9e-29 100.6 0.1 1.3e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 ML-like domain FRG2 PF15315.6 OAJ17271.1 - 0.028 14.6 0.2 0.053 13.7 0.2 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Abhydrolase_3 PF07859.13 OAJ17272.1 - 5.7e-30 104.7 0.0 7.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 OAJ17272.1 - 0.015 14.8 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 OAJ17272.1 - 0.055 12.3 0.2 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Say1_Mug180 PF10340.9 OAJ17272.1 - 0.31 9.8 0.0 0.43 9.4 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Ribosomal_L27 PF01016.19 OAJ17273.1 - 6.7e-35 119.0 0.6 1.3e-34 118.0 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein WD40 PF00400.32 OAJ17274.1 - 2.1e-53 177.1 23.7 1.7e-06 28.6 0.3 11.8 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 OAJ17274.1 - 4.2e-41 140.2 0.0 1.3e-40 138.6 0.0 1.8 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OAJ17274.1 - 3.8e-11 43.1 0.0 0.041 14.2 0.0 7.8 7 1 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ17274.1 - 1.9e-08 33.4 0.3 0.035 12.8 0.0 5.0 4 1 0 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ17274.1 - 0.00014 20.7 1.1 0.088 11.5 0.0 3.8 2 1 2 4 4 4 1 Nup133 N terminal like Ge1_WD40 PF16529.5 OAJ17274.1 - 0.037 13.0 0.0 0.62 9.0 0.0 3.0 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 OAJ17275.1 - 8.1e-05 23.3 2.8 0.7 10.9 0.1 3.9 4 1 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.11 OAJ17275.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Aldedh PF00171.22 OAJ17276.1 - 2.2e-126 422.1 0.0 2.9e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAJ17276.1 - 0.066 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Metallophos PF00149.28 OAJ17277.1 - 1.6e-34 120.2 0.3 2e-34 119.9 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ17277.1 - 0.32 11.5 2.1 0.67 10.4 2.1 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ribosomal_S2 PF00318.20 OAJ17278.1 - 7.8e-52 175.6 0.0 1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.20 OAJ17279.1 - 3.3e-231 768.7 7.5 4.1e-231 768.4 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ17279.1 - 2.3e-19 69.4 0.7 1.6e-18 66.6 0.7 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAJ17279.1 - 0.00067 19.4 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OAJ17279.1 - 0.0043 16.1 0.2 0.042 12.8 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 OAJ17279.1 - 0.01 15.1 0.4 0.024 13.9 0.4 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 OAJ17279.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein Tyrosinase PF00264.20 OAJ17292.1 - 5.6e-24 85.7 8.9 7.4e-12 46.0 0.1 2.3 1 1 1 2 2 2 2 Common central domain of tyrosinase LRR_6 PF13516.6 OAJ17294.1 - 9.6e-06 25.3 2.0 0.023 14.7 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 OAJ17294.1 - 0.043 14.3 0.2 0.079 13.4 0.2 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ17294.1 - 0.091 13.4 0.0 2.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 OAJ17295.1 - 0.0028 17.6 0.4 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeat Cytotoxic PF09000.10 OAJ17295.1 - 0.084 13.2 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Cytotoxic Serglycin PF04360.12 OAJ17295.1 - 8.6 6.3 6.9 29 4.6 6.9 1.9 1 1 0 1 1 1 0 Serglycin Homeodomain PF00046.29 OAJ17296.1 - 7.8e-19 67.3 4.0 2e-18 65.9 4.0 1.8 1 0 0 1 1 1 1 Homeodomain zf-C3HC4 PF00097.25 OAJ17297.1 - 5.8e-08 32.5 1.8 5.8e-08 32.5 1.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ17297.1 - 1.4e-06 28.1 2.2 4e-05 23.4 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ17297.1 - 3.6e-06 26.9 4.2 6.9e-06 26.0 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ17297.1 - 3.4e-05 23.6 2.5 3.4e-05 23.6 2.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ17297.1 - 9e-05 22.7 1.7 9e-05 22.7 1.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ17297.1 - 0.00028 21.0 1.7 0.00056 20.0 1.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ17297.1 - 0.00064 19.6 2.0 0.00064 19.6 2.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ17297.1 - 0.0015 18.3 4.6 0.0038 17.1 2.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1644 PF07800.12 OAJ17297.1 - 0.44 10.6 3.6 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Cation_efflux PF01545.21 OAJ17298.1 - 0.00052 19.8 0.1 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 Cation efflux family Sde2_N_Ubi PF13019.6 OAJ17298.1 - 0.65 9.8 4.1 2.7 7.8 4.1 2.0 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Phage_integrase PF00589.22 OAJ17299.1 - 0.029 14.2 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family Peptidase_M16 PF00675.20 OAJ17301.1 - 4.7e-52 175.9 2.1 1.3e-51 174.6 0.8 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ17301.1 - 9.3e-42 143.1 0.0 3.4e-38 131.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 OAJ17301.1 - 0.083 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Fe-S_biosyn PF01521.20 OAJ17302.1 - 6.6e-11 42.4 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATP-synt_C PF00137.21 OAJ17303.1 - 1e-33 115.4 36.7 8.8e-22 77.2 15.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 OAJ17303.1 - 6.4 6.6 7.2 5.1 6.9 5.8 1.6 1 1 0 1 1 1 0 Inclusion membrane protein D DNA_pol_delta_4 PF04081.13 OAJ17304.1 - 6.6e-27 94.4 0.1 9.4e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 PTPlike_phytase PF14566.6 OAJ17305.1 - 2.8e-124 410.9 0.5 7.5e-50 169.1 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 OAJ17305.1 - 0.00042 20.2 0.0 1.8 8.4 0.0 3.8 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ17305.1 - 0.0029 17.2 0.4 14 5.2 0.1 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 OAJ17305.1 - 0.15 11.7 0.0 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF2025 PF09634.10 OAJ17306.1 - 0.035 14.1 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) BCS1_N PF08740.11 OAJ17307.1 - 1.7e-50 171.6 0.0 2.5e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAJ17307.1 - 4.6e-17 62.7 0.0 2.6e-16 60.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ17307.1 - 0.00018 20.7 0.0 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OAJ17307.1 - 0.001 19.5 1.4 0.011 16.1 0.8 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 OAJ17307.1 - 0.0014 18.3 0.0 0.13 11.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAJ17307.1 - 0.0052 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 OAJ17307.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 OAJ17307.1 - 0.026 14.4 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OAJ17307.1 - 0.037 14.0 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAJ17307.1 - 0.043 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OAJ17307.1 - 0.081 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAJ17307.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain E1_dh PF00676.20 OAJ17308.1 - 1.8e-60 204.4 0.0 3e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 OAJ17308.1 - 3.9e-60 202.6 0.0 5.8e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OAJ17308.1 - 6.3e-52 175.3 0.0 1.1e-51 174.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAJ17308.1 - 2.7e-16 58.9 0.1 6.2e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus EBP PF05241.12 OAJ17309.1 - 1.5e-60 203.7 10.1 1.7e-60 203.5 10.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein HR_lesion PF05514.11 OAJ17309.1 - 0.00098 19.3 1.1 0.48 10.6 0.1 2.5 2 0 0 2 2 2 2 HR-like lesion-inducing NAD_binding_8 PF13450.6 OAJ17309.1 - 0.012 15.8 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TMEM208_SND2 PF05620.11 OAJ17309.1 - 0.26 11.1 8.1 0.63 9.8 1.0 2.5 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Nas2_N PF18265.1 OAJ17310.1 - 6.6e-27 93.2 0.6 8.7e-27 92.9 0.6 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAJ17310.1 - 4.4e-09 36.0 0.1 8.3e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAJ17310.1 - 2.2e-05 24.7 0.0 5.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAJ17310.1 - 0.00094 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAJ17310.1 - 0.015 15.7 0.0 0.042 14.2 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain PAP_PilO PF06864.12 OAJ17311.1 - 0.026 13.4 0.0 0.03 13.2 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) IPTL-CTERM PF18203.1 OAJ17311.1 - 0.29 11.1 5.2 0.49 10.4 0.4 2.8 2 0 0 2 2 2 0 IPTL-CTERM motif Mito_carr PF00153.27 OAJ17312.1 - 7.3e-43 144.4 9.7 6.3e-17 61.3 0.8 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad4 PF03835.15 OAJ17313.1 - 4.8e-26 91.2 0.0 4.8e-26 91.2 0.0 1.8 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAJ17313.1 - 3.7e-25 88.1 0.2 8.3e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAJ17313.1 - 3.7e-19 68.3 0.1 7.1e-19 67.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 OAJ17313.1 - 7e-09 36.1 0.0 6.7e-08 33.0 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily BHD_2 PF10404.9 OAJ17313.1 - 1.6e-05 25.7 0.8 1.6e-05 25.7 0.8 3.6 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Cnd3 PF12719.7 OAJ17314.1 - 1.9e-75 253.8 0.0 3e-74 249.9 0.0 2.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 OAJ17314.1 - 0.00073 19.9 11.5 0.01 16.2 0.2 5.6 5 2 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 OAJ17314.1 - 0.0052 16.8 3.3 2 8.5 0.1 4.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ17314.1 - 0.0092 16.2 6.9 43 4.7 0.1 6.4 7 0 0 7 7 7 0 HEAT repeat RTP1_C1 PF10363.9 OAJ17314.1 - 0.57 10.4 2.6 1.5 9.0 0.1 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Gly_transf_sug PF04488.15 OAJ17328.1 - 3.2e-21 75.8 0.1 5.9e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAJ17328.1 - 0.04 13.2 0.4 0.6 9.3 0.3 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Ribosomal_L12_N PF16320.5 OAJ17329.1 - 0.74 9.6 5.8 0.13 11.9 0.4 2.7 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Exonuc_VII_L PF02601.15 OAJ17329.1 - 2.5 7.6 15.1 6.3 6.3 15.1 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pkinase PF00069.25 OAJ17330.1 - 7.1e-73 245.2 0.0 1.1e-72 244.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17330.1 - 2.6e-33 115.4 0.0 4.5e-33 114.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ17330.1 - 8e-05 22.1 2.7 2.7 7.2 0.1 3.2 2 1 1 3 3 3 3 Kinase-like APH PF01636.23 OAJ17330.1 - 0.0014 18.6 0.1 0.55 10.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ17330.1 - 0.0027 16.6 0.0 0.0094 14.8 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAJ17330.1 - 0.13 11.8 1.7 0.51 9.9 1.7 1.8 1 1 0 1 1 1 0 RIO1 family Ran_BP1 PF00638.18 OAJ17331.1 - 2.3e-51 173.1 1.9 3.7e-51 172.5 1.9 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OAJ17331.1 - 3.5e-06 26.9 1.0 2.1e-05 24.4 1.0 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 OAJ17331.1 - 0.00046 19.9 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) VID27_PH PF17747.1 OAJ17331.1 - 0.0073 16.6 0.1 0.01 16.1 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain DUF4358 PF14270.6 OAJ17331.1 - 0.1 12.9 0.4 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) MIP PF00230.20 OAJ17332.1 - 2e-05 24.4 7.8 3.5e-05 23.6 7.8 1.3 1 0 0 1 1 1 1 Major intrinsic protein CTU2 PF10288.9 OAJ17333.1 - 4 7.7 7.8 8.9 6.6 0.1 3.4 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 DNA_pol_phi PF04931.13 OAJ17333.1 - 8.2 4.4 5.5 14 3.6 5.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Hist_deacetyl PF00850.19 OAJ17334.1 - 5.4e-84 282.3 0.0 7.4e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAJ17334.1 - 6.8e-10 38.5 0.0 0.00025 20.2 0.0 3.4 4 0 0 4 4 4 2 Arb2 domain Glyco_trans_2_3 PF13632.6 OAJ17335.1 - 1.3e-19 70.9 5.7 1.3e-19 70.9 5.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAJ17335.1 - 4.2e-19 69.4 0.0 5.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ17335.1 - 9.6e-10 38.2 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ17335.1 - 4.9e-07 29.7 0.0 8.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 TMEM52 PF14979.6 OAJ17335.1 - 0.14 12.0 0.1 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Transmembrane 52 MRP-L20 PF12824.7 OAJ17336.1 - 1.7e-18 67.3 0.3 3.1e-18 66.5 0.3 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 APG12 PF04110.13 OAJ17337.1 - 6.9e-32 109.7 0.0 8.6e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OAJ17337.1 - 0.0047 17.1 0.0 0.0055 16.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like FliP PF00813.20 OAJ17337.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 FliP family RINT1_TIP1 PF04437.13 OAJ17339.1 - 8e-63 213.0 0.0 1.2e-61 209.2 0.0 2.8 1 1 0 1 1 1 1 RINT-1 / TIP-1 family Pex14_N PF04695.13 OAJ17340.1 - 0.085 13.5 1.0 0.085 13.5 1.0 3.0 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.9 OAJ17340.1 - 1 9.0 13.6 1.7 8.2 13.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_11 PF08241.12 OAJ17341.1 - 4e-09 37.0 0.0 6.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ17341.1 - 2.2e-08 34.7 0.1 4.1e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ17341.1 - 0.00011 22.1 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ17341.1 - 0.00018 22.2 0.0 0.0006 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ17341.1 - 0.0036 17.1 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 OAJ17342.1 - 3.7e-27 95.6 0.0 4.9e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ17342.1 - 1.2e-07 31.5 0.0 0.00056 19.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ17342.1 - 0.00028 20.8 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OAJ17342.1 - 0.014 15.4 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 OAJ17342.1 - 0.015 15.9 0.2 0.024 15.3 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Syntaxin-18_N PF10496.9 OAJ17343.1 - 1.5e-08 34.8 0.1 1.5e-08 34.8 0.1 2.9 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAJ17343.1 - 0.056 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 SNARE domain Speriolin_N PF15058.6 OAJ17343.1 - 0.85 9.7 7.6 0.18 11.9 3.6 2.0 1 1 1 2 2 2 0 Speriolin N terminus K_channel_TID PF07941.11 OAJ17343.1 - 7 7.2 17.8 0.13 12.8 7.4 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain G-patch PF01585.23 OAJ17344.1 - 0.0098 15.8 0.7 0.05 13.5 0.5 2.3 2 0 0 2 2 2 1 G-patch domain SHS2_Rpb7-N PF03876.17 OAJ17345.1 - 8.7e-14 51.6 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ17345.1 - 1.2e-13 51.2 0.1 1.7e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OAJ17345.1 - 0.08 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 AFG1_ATPase PF03969.16 OAJ17346.1 - 1e-51 176.0 0.0 7.2e-38 130.4 0.0 3.9 3 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 OAJ17346.1 - 2.6e-08 34.4 0.0 2.6e-08 34.4 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ17346.1 - 0.00017 21.6 0.0 0.044 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ17346.1 - 0.0002 21.6 0.0 0.013 15.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 OAJ17346.1 - 0.0013 19.2 0.0 0.028 14.8 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAJ17346.1 - 0.0035 17.7 0.0 1.7 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 OAJ17346.1 - 0.006 16.3 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 OAJ17346.1 - 0.0079 15.6 0.0 0.024 14.0 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ17346.1 - 0.12 12.1 0.0 1.1 9.0 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAJ17346.1 - 0.16 11.5 1.8 2.6 7.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain BCDHK_Adom3 PF10436.9 OAJ17347.1 - 4e-40 137.3 0.0 6.1e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ17347.1 - 1.1e-09 38.7 0.0 2.5e-05 24.7 0.0 2.7 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DAO PF01266.24 OAJ17361.1 - 2.3e-35 122.8 0.1 8.7e-35 120.9 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ17361.1 - 1.4e-05 25.2 0.3 6e-05 23.2 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAJ17361.1 - 0.058 12.5 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Sacchrp_dh_NADP PF03435.18 OAJ17361.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Coatomer_WDAD PF04053.14 OAJ17363.1 - 1.4e-135 452.8 0.0 2.2e-135 452.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAJ17363.1 - 2.8e-97 326.0 0.0 3.6e-97 325.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAJ17363.1 - 1.4e-41 139.7 13.9 1.8e-08 34.9 0.4 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17363.1 - 1.6e-12 47.6 0.2 0.0011 19.3 0.0 6.4 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OAJ17363.1 - 0.0085 16.0 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_2 PF07719.17 OAJ17363.1 - 0.11 12.6 0.1 13 6.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.8 OAJ17363.1 - 0.15 10.7 4.8 1.5 7.4 0.0 3.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 OAJ17363.1 - 2.4 9.2 11.4 1.4e+02 3.7 0.3 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Catalase PF00199.19 OAJ17364.1 - 8.7e-170 564.9 0.1 1.2e-169 564.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ17364.1 - 1.6e-15 57.0 0.0 4.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Crl PF07417.12 OAJ17364.1 - 0.68 10.0 2.8 0.5 10.4 0.2 2.0 2 0 0 2 2 2 0 Sigma factor-binding transcriptional regulator Crl M20_dimer PF07687.14 OAJ17365.1 - 9.1e-09 35.2 0.1 1.8e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAJ17365.1 - 1.1e-06 28.5 0.1 2e-06 27.7 0.2 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 EHN PF06441.12 OAJ17367.1 - 5.5e-25 87.8 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ17367.1 - 1.8e-09 37.6 0.1 3.7e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TFIID-31kDa PF02291.15 OAJ17368.1 - 1.7e-45 154.0 0.0 2.1e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAJ17368.1 - 0.0029 17.6 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated MAD PF05557.13 OAJ17369.1 - 4.8e-37 127.7 55.0 1.5e-33 116.1 10.3 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein HALZ PF02183.18 OAJ17369.1 - 0.00012 22.2 23.4 0.055 13.7 0.3 5.7 6 0 0 6 6 6 3 Homeobox associated leucine zipper VQ PF05678.14 OAJ17369.1 - 0.075 12.5 0.5 0.15 11.6 0.5 1.5 1 0 0 1 1 1 0 VQ motif KIAA1430 PF13879.6 OAJ17369.1 - 0.15 12.8 0.2 0.15 12.8 0.2 3.0 3 1 0 3 3 3 0 KIAA1430 homologue Adhesin_P1_N PF18652.1 OAJ17369.1 - 1.1 9.3 8.9 5.6 7.1 1.4 3.6 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain APC_N_CC PF16689.5 OAJ17369.1 - 3.7 7.7 7.1 1.9 8.6 0.6 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain GMC_oxred_N PF00732.19 OAJ17370.1 - 3.9e-63 213.6 0.0 5.2e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ17370.1 - 5e-27 95.2 0.0 1e-26 94.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ17370.1 - 1.2e-06 27.9 0.0 3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ17370.1 - 1.3e-05 25.3 2.5 2.4e-05 24.5 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAJ17370.1 - 1.7e-05 24.1 0.0 3.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAJ17370.1 - 3.6e-05 23.5 1.2 8.4e-05 22.3 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ17370.1 - 0.00019 20.7 1.1 0.00023 20.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ17370.1 - 0.007 15.6 0.1 0.014 14.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAJ17370.1 - 0.043 12.7 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 OAJ17370.1 - 0.054 12.2 0.6 0.2 10.3 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 OAJ17370.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ17370.1 - 0.32 11.3 1.3 1.9 8.7 0.2 2.6 3 0 0 3 3 3 0 TrkA-N domain SF1-HH PF16275.5 OAJ17371.1 - 8e-39 132.5 1.0 1.3e-38 131.8 1.0 1.3 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 OAJ17371.1 - 3.9e-10 39.3 14.5 6.9e-05 22.7 2.3 2.8 3 0 0 3 3 3 2 Zinc knuckle DUF1897 PF09005.10 OAJ17371.1 - 8.4e-09 34.8 14.2 0.0001 21.7 1.4 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) zf-CCHC_3 PF13917.6 OAJ17371.1 - 4.9e-07 29.6 10.6 0.00015 21.7 3.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 OAJ17371.1 - 7e-07 29.0 0.2 1.3e-06 28.1 0.2 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_2 PF13696.6 OAJ17371.1 - 0.3 10.9 14.9 0.45 10.4 5.1 2.5 2 0 0 2 2 2 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.6 OAJ17371.1 - 6.8 7.6 6.9 14 6.6 6.9 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon adh_short PF00106.25 OAJ17372.1 - 7.4e-40 136.5 0.2 1.1e-39 135.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ17372.1 - 1.2e-38 132.9 0.4 3e-38 131.7 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ17372.1 - 3.5e-08 33.6 0.8 1.3e-07 31.7 0.8 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ17372.1 - 0.00066 19.2 0.9 0.0022 17.5 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ17372.1 - 0.0012 18.3 0.4 0.0079 15.6 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 OAJ17372.1 - 0.032 13.6 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 OAJ17372.1 - 0.079 13.0 0.1 0.23 11.5 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Robl_LC7 PF03259.17 OAJ17373.1 - 8.1e-07 28.7 0.0 1.3e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Roadblock/LC7 domain UPF0449 PF15136.6 OAJ17373.1 - 0.062 13.8 0.5 0.13 12.8 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Herpes_capsid PF06112.11 OAJ17374.1 - 4.9 7.2 8.4 5.8 7.0 8.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF515 PF04415.12 OAJ17375.1 - 0.55 8.6 3.6 0.63 8.4 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Methyltransf_2 PF00891.18 OAJ17378.1 - 6.1e-21 74.7 0.0 1.1e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 OAJ17378.1 - 0.017 15.0 0.5 5.4 7.0 0.1 2.8 2 0 0 2 2 2 0 MarR family RPA_C PF08784.11 OAJ17378.1 - 0.021 15.4 0.1 0.08 13.6 0.0 2.0 2 0 0 2 2 2 0 Replication protein A C terminal Methyltransf_12 PF08242.12 OAJ17378.1 - 0.026 15.3 0.0 0.073 13.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M43 PF05572.13 OAJ17379.1 - 4e-08 33.3 0.1 8.2e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ17379.1 - 0.023 15.2 0.0 0.085 13.4 0.0 2.1 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ17379.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12 Mo25 PF08569.11 OAJ17381.1 - 6e-130 433.4 0.0 1.4e-129 432.1 0.0 1.6 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 OAJ17381.1 - 0.025 14.9 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats Spore_GerQ PF09671.10 OAJ17381.1 - 0.034 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) DDE_Tnp_4 PF13359.6 OAJ17397.1 - 9.9e-17 61.0 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Fe-ADH PF00465.19 OAJ17398.1 - 3.1e-68 230.3 0.0 4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ17398.1 - 1.3e-15 57.8 0.2 1e-08 35.2 0.0 2.3 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OAJ17398.1 - 0.024 13.8 0.0 0.37 9.9 0.0 2.2 2 0 0 2 2 2 0 3-dehydroquinate synthase PFK PF00365.20 OAJ17398.1 - 0.037 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase TPR_9 PF13371.6 OAJ17398.1 - 0.11 12.7 0.1 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Cauli_VI PF01693.16 OAJ17399.1 - 2.3e-16 59.8 1.1 3.9e-16 59.1 1.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RRF PF01765.19 OAJ17400.1 - 2e-32 112.4 0.1 3e-32 111.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Tho2 PF11262.8 OAJ17400.1 - 3.8 6.6 6.0 5.7 6.0 6.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pentapeptide_2 PF01469.18 OAJ17401.1 - 0.074 13.0 1.0 0.18 11.7 1.0 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Cauli_VI PF01693.16 OAJ17402.1 - 1.6e-14 53.9 1.5 2.8e-14 53.1 1.5 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF4805 PF16063.5 OAJ17403.1 - 0.21 10.9 3.2 0.95 8.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Myb_DNA-bind_6 PF13921.6 OAJ17404.1 - 0.0092 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 OAJ17404.1 - 0.092 12.8 0.4 1.9 8.6 0.3 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3138 PF11336.8 OAJ17404.1 - 0.14 10.8 2.0 0.21 10.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SDA1 PF05285.12 OAJ17404.1 - 0.28 10.5 4.1 0.36 10.2 4.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ17404.1 - 0.67 8.1 5.6 0.95 7.6 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family RNase_H PF00075.24 OAJ17406.1 - 8.4e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 OAJ17406.1 - 2.3e-19 69.4 0.3 3.7e-19 68.8 0.3 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyco_hydro_8 PF01270.17 OAJ17407.1 - 5.4e-15 55.1 0.1 1.1e-14 54.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.15 OAJ17407.1 - 0.098 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease THOC7 PF05615.13 OAJ17408.1 - 8.7e-22 77.8 3.2 8.7e-22 77.8 3.2 2.8 2 1 1 3 3 3 1 Tho complex subunit 7 IFT20 PF14931.6 OAJ17408.1 - 0.003 17.7 2.4 0.054 13.7 0.2 2.6 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 Occludin_ELL PF07303.13 OAJ17408.1 - 0.024 15.4 1.2 0.074 13.8 1.2 1.9 1 0 0 1 1 1 0 Occludin homology domain FAM76 PF16046.5 OAJ17408.1 - 0.032 13.6 0.3 0.032 13.6 0.3 2.8 3 0 0 3 3 3 0 FAM76 protein DUF641 PF04859.12 OAJ17408.1 - 0.098 13.0 0.1 0.098 13.0 0.1 2.5 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 OAJ17408.1 - 0.2 11.5 2.7 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_TATA_bd PF12325.8 OAJ17408.1 - 0.46 10.7 4.8 0.46 10.7 2.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ribosomal_L29 PF00831.23 OAJ17408.1 - 5.9 6.9 7.1 6.5 6.8 0.6 3.1 3 0 0 3 3 3 0 Ribosomal L29 protein SUIM_assoc PF16619.5 OAJ17409.1 - 0.0051 16.8 20.0 0.051 13.6 2.0 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 SPX PF03105.19 OAJ17409.1 - 0.39 10.6 20.9 0.074 13.0 17.0 1.7 2 0 0 2 2 2 0 SPX domain Spt20 PF12090.8 OAJ17409.1 - 0.57 9.8 13.8 2.3 7.8 3.2 2.2 2 0 0 2 2 2 0 Spt20 family HicB_lk_antitox PF15919.5 OAJ17410.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Nbs1_C PF08599.10 OAJ17410.1 - 0.36 11.0 3.4 0.29 11.3 0.3 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 MPP6 PF10175.9 OAJ17411.1 - 0.0073 16.8 14.5 0.098 13.2 6.0 2.9 1 1 1 2 2 2 2 M-phase phosphoprotein 6 FYDLN_acid PF09538.10 OAJ17411.1 - 0.13 13.0 5.5 0.33 11.6 5.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PGA2 PF07543.12 OAJ17411.1 - 1.2 9.1 7.2 0.17 11.8 1.0 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 OAJ17411.1 - 1.9 6.5 7.1 2.3 6.2 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SPT16 PF08644.11 OAJ17412.1 - 1.3e-52 178.0 0.3 3.4e-52 176.6 0.0 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAJ17412.1 - 9.9e-44 149.0 0.4 2.8e-43 147.5 0.4 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAJ17412.1 - 6.4e-26 91.3 0.0 1.2e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAJ17412.1 - 2.4e-15 56.7 0.1 6.8e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Atg8 PF02991.16 OAJ17413.1 - 4.3e-52 174.7 0.2 5e-52 174.4 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAJ17413.1 - 6.3e-07 29.7 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HEAT PF02985.22 OAJ17414.1 - 6.8e-12 44.6 16.9 0.0075 16.4 0.0 9.3 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 OAJ17414.1 - 6.1e-06 26.5 17.0 0.0024 18.2 0.2 5.9 4 2 2 6 6 6 4 HEAT repeats Cnd1 PF12717.7 OAJ17414.1 - 9.3e-05 22.5 5.3 0.0013 18.8 0.1 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ17414.1 - 0.075 11.6 6.0 0.59 8.6 0.1 2.5 3 0 0 3 3 3 0 Adaptin N terminal region Pribosyltran PF00156.27 OAJ17415.1 - 0.0007 19.1 0.1 0.0044 16.5 0.1 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Mt_ATP-synt_D PF05873.12 OAJ17416.1 - 1.4e-14 54.3 0.6 1.8e-14 53.9 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Cauli_AT PF03233.13 OAJ17416.1 - 0.019 14.9 0.8 0.03 14.3 0.8 1.4 1 0 0 1 1 1 0 Aphid transmission protein Peptidase_M17_N PF02789.17 OAJ17416.1 - 0.031 14.2 1.6 0.041 13.7 0.1 1.8 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain RPW8 PF05659.11 OAJ17416.1 - 0.034 13.8 2.5 0.3 10.8 0.9 2.6 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 OAJ17416.1 - 0.04 13.2 3.2 0.05 12.9 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1366 PF07104.11 OAJ17416.1 - 0.054 13.2 3.6 0.11 12.2 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1366) Prominin PF05478.11 OAJ17416.1 - 0.13 10.2 0.2 0.15 10.0 0.2 1.0 1 0 0 1 1 1 0 Prominin DUF2408 PF10303.9 OAJ17416.1 - 0.19 12.3 3.6 0.81 10.2 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) MbeB_N PF04837.12 OAJ17416.1 - 1.8 8.9 6.5 0.2 12.0 0.9 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region APG6_N PF17675.1 OAJ17416.1 - 2.4 8.7 7.3 6.7 7.3 7.3 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region NAPRTase PF04095.16 OAJ17417.1 - 1.6e-46 158.9 0.1 1.1e-20 74.3 0.0 3.3 3 0 0 3 3 3 3 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAJ17417.1 - 5.3e-32 110.8 0.1 8e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4219 PF13961.6 OAJ17418.1 - 0.0044 16.6 0.0 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 OAJ17418.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cys_Met_Meta_PP PF01053.20 OAJ17419.1 - 8.8e-119 396.4 0.0 1.3e-118 395.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 OAJ17419.1 - 5.4e-13 49.0 4.2 1.6e-12 47.4 4.2 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ17419.1 - 8.2e-06 26.1 1.2 4.1e-05 23.9 0.0 2.7 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAJ17419.1 - 0.00075 19.0 0.1 0.0017 17.9 0.1 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature UQ_con PF00179.26 OAJ17432.1 - 2.4e-43 147.2 0.0 2.7e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA PF00004.29 OAJ17434.1 - 2.3e-14 54.0 0.0 4.6e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ17434.1 - 9.3e-12 45.0 0.0 1.8e-10 40.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OAJ17434.1 - 4.8e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 OAJ17434.1 - 6.9e-06 26.4 0.0 2.1e-05 24.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.15 OAJ17434.1 - 5.4e-05 23.2 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_19 PF13245.6 OAJ17434.1 - 0.00013 22.3 0.0 0.00086 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 OAJ17434.1 - 0.00019 21.3 0.0 0.00055 19.7 0.0 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_28 PF13521.6 OAJ17434.1 - 0.00041 20.6 0.2 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ17434.1 - 0.00043 20.1 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 OAJ17434.1 - 0.00049 20.4 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 OAJ17434.1 - 0.00056 20.3 0.1 0.0099 16.3 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 OAJ17434.1 - 0.00064 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OAJ17434.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ17434.1 - 0.0021 17.8 0.0 0.0062 16.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAJ17434.1 - 0.0051 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ17434.1 - 0.0097 15.3 0.0 0.045 13.1 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI MCM PF00493.23 OAJ17434.1 - 0.018 14.1 0.1 2.1 7.4 0.0 2.9 3 0 0 3 3 3 0 MCM P-loop domain AAA_7 PF12775.7 OAJ17434.1 - 0.021 14.4 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 OAJ17434.1 - 0.042 13.9 0.0 1.7 8.6 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OAJ17434.1 - 0.07 13.1 0.5 0.65 10.0 0.5 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAJ17434.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) p450 PF00067.22 OAJ17436.1 - 1e-53 182.7 0.0 1.3e-53 182.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RabGAP-TBC PF00566.18 OAJ17437.1 - 3.3e-50 170.7 0.0 5.5e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Metal_resist PF13801.6 OAJ17437.1 - 2.2 8.5 13.6 0.16 12.1 3.9 3.0 3 0 0 3 3 3 0 Heavy-metal resistance PfkB PF00294.24 OAJ17438.1 - 3e-34 118.7 0.4 3.9e-34 118.3 0.4 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HECT PF00632.25 OAJ17439.1 - 1.6e-97 326.7 0.0 2.1e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UQ_con PF00179.26 OAJ17440.1 - 9.4e-23 80.4 0.0 1.1e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme p450 PF00067.22 OAJ17441.1 - 2.3e-54 184.9 0.0 2.9e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GldM_N PF12081.8 OAJ17441.1 - 0.22 11.6 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 GldM N-terminal domain p450 PF00067.22 OAJ17442.1 - 6.6e-53 180.1 0.0 8.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Smg4_UPF3 PF03467.15 OAJ17443.1 - 3.8e-54 183.3 0.9 3.8e-54 183.3 0.9 4.6 3 2 0 3 3 3 1 Smg-4/UPF3 family LIAS_N PF16881.5 OAJ17443.1 - 0.046 14.1 0.3 0.046 14.1 0.3 3.4 3 1 1 4 4 4 0 N-terminal domain of lipoyl synthase of Radical_SAM family RRM_2 PF04059.12 OAJ17443.1 - 0.096 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 p450 PF00067.22 OAJ17444.1 - 3.4e-54 184.3 0.0 4.5e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAJ17445.1 - 2.3e-49 168.4 0.0 3.1e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 OAJ17446.1 - 1.8e-45 152.8 6.3 6.5e-16 58.0 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.19 OAJ17447.1 - 4e-40 137.1 0.0 9.4e-30 103.3 0.1 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ17447.1 - 2.2e-24 85.6 0.0 3.1e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF3961 PF13106.6 OAJ17447.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Tudor_3 PF18115.1 OAJ17448.1 - 0.00019 21.2 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR PF00567.24 OAJ17448.1 - 0.00065 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Tudor domain LBR_tudor PF09465.10 OAJ17448.1 - 0.0035 17.1 0.1 0.0059 16.4 0.1 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain SMN PF06003.12 OAJ17448.1 - 0.008 15.5 0.0 0.008 15.5 0.0 2.0 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) Agenet PF05641.12 OAJ17448.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Agenet domain Tudor_2 PF18104.1 OAJ17448.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Rotamase_2 PF13145.6 OAJ17448.1 - 5.2 7.9 12.1 0.21 12.4 1.3 2.5 2 1 0 2 2 2 0 PPIC-type PPIASE domain Sugar_tr PF00083.24 OAJ17449.1 - 2.4e-49 168.4 12.1 3.1e-49 168.1 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ17449.1 - 1.8e-24 86.4 20.3 6.5e-15 54.9 7.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ17449.1 - 0.0003 19.2 2.3 0.0029 16.0 0.0 2.8 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF1168 PF06658.12 OAJ17450.1 - 4.9e-38 130.0 14.6 8.8e-38 129.2 14.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF966 PF06136.13 OAJ17450.1 - 0.18 11.5 7.5 0.23 11.2 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 OAJ17450.1 - 5 5.8 4.9 5.3 5.7 4.9 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S24 PF00717.23 OAJ17451.1 - 2.7e-06 27.2 0.0 6.5e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 OAJ17451.1 - 0.026 14.3 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Trypsin_2 PF13365.6 OAJ17452.1 - 1.7e-07 32.3 1.3 0.0053 17.7 1.2 2.7 1 1 1 2 2 2 2 Trypsin-like peptidase domain DUF2532 PF10811.8 OAJ17452.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) USP7_ICP0_bdg PF12436.8 OAJ17453.1 - 1.3e-83 280.0 0.1 3.4e-82 275.4 0.0 2.6 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAJ17453.1 - 7.1e-65 218.6 4.7 5.1e-64 215.8 2.1 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAJ17453.1 - 3.5e-50 170.9 1.0 2.5e-49 168.1 0.6 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ17453.1 - 6.3e-23 81.9 0.0 2.1e-22 80.2 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAJ17453.1 - 1.9e-08 34.5 0.0 1.1e-07 32.0 0.0 2.3 2 1 1 3 3 3 1 MATH domain DUF1688 PF07958.11 OAJ17467.1 - 3.1e-155 517.1 0.0 2e-154 514.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) NDUFA12 PF05071.16 OAJ17468.1 - 7.7e-30 103.6 0.1 1.1e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTH2 PF01981.16 OAJ17469.1 - 5.6e-45 152.4 0.7 7.7e-45 152.0 0.7 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_11 PF13414.6 OAJ17469.1 - 0.022 14.4 0.3 0.048 13.3 0.3 1.5 1 0 0 1 1 1 0 TPR repeat Nuc_deoxyrib_tr PF05014.15 OAJ17469.1 - 0.1 12.6 0.4 0.28 11.2 0.1 1.8 1 1 1 2 2 2 0 Nucleoside 2-deoxyribosyltransferase Lectin_leg-like PF03388.13 OAJ17470.1 - 4.6e-59 199.6 0.0 6.1e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 OAJ17470.1 - 0.02 14.4 0.0 0.78 9.2 0.0 2.3 1 1 0 1 1 1 0 Legume lectin domain DFRP_C PF16543.5 OAJ17471.1 - 7.9e-28 96.8 0.3 7.9e-28 96.8 0.3 3.7 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_3 PF15663.5 OAJ17471.1 - 0.00036 20.7 0.6 0.038 14.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 OAJ17471.1 - 0.049 14.3 8.0 11 6.7 4.4 3.8 3 1 0 3 3 3 0 Torus domain Ribosomal_L5 PF00281.19 OAJ17471.1 - 0.5 10.7 5.4 9.8 6.6 1.3 2.6 2 0 0 2 2 2 0 Ribosomal protein L5 zf-CCCH_2 PF14608.6 OAJ17471.1 - 3.6 8.2 11.2 8.3 7.0 1.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Transket_pyr PF02779.24 OAJ17472.1 - 4.7e-48 163.2 0.0 9.2e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ17472.1 - 4.5e-40 136.4 0.2 1.3e-39 134.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Nup160 PF11715.8 OAJ17473.1 - 2e-15 56.5 0.0 1.8e-10 40.1 0.0 3.2 3 1 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC3 PF12895.7 OAJ17473.1 - 0.0028 17.9 0.1 0.016 15.4 0.1 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAJ17473.1 - 0.013 16.0 6.0 0.45 11.3 0.6 5.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ17473.1 - 0.11 13.1 13.0 0.25 11.9 2.7 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RPA_C PF08784.11 OAJ17475.1 - 4.9e-10 40.0 1.2 9.5e-10 39.1 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAJ17475.1 - 3.4e-09 36.6 0.1 5.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OAJ17475.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 BOF PF04076.13 OAJ17475.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein HTH_20 PF12840.7 OAJ17475.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain KTI12 PF08433.10 OAJ17476.1 - 6e-56 189.9 0.0 1e-55 189.1 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAJ17476.1 - 2.9e-10 40.5 0.0 5.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ17476.1 - 0.0004 20.9 0.0 0.00093 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain LCCL PF03815.19 OAJ17478.1 - 8.7e-15 54.6 0.0 1.7e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Profilin PF00235.19 OAJ17479.1 - 4.4e-48 162.7 0.1 4.9e-48 162.6 0.1 1.0 1 0 0 1 1 1 1 Profilin ComX PF05952.12 OAJ17479.1 - 0.14 12.1 0.1 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacillus competence pheromone ComX MOZART1 PF12554.8 OAJ17480.1 - 4.8e-16 58.3 0.1 5.7e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UPF0181 PF03701.14 OAJ17480.1 - 0.031 13.9 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Cas_Csa5 PF09702.10 OAJ17480.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) 4F5 PF04419.14 OAJ17481.1 - 2.9e-09 37.6 10.2 2.9e-09 37.6 10.2 2.2 2 0 0 2 2 2 1 4F5 protein family Chs7 PF12271.8 OAJ17482.1 - 7.6e-50 169.9 9.0 9.4e-50 169.6 9.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2852 PF11014.8 OAJ17482.1 - 1.5 9.0 5.5 1.8 8.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) XPG_I PF00867.18 OAJ17483.1 - 1.8e-15 57.1 0.0 1.3e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAJ17483.1 - 2.8e-06 27.7 0.0 9e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 OAJ17483.1 - 0.0086 17.0 1.0 0.0086 17.0 1.0 5.7 4 4 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain Syja_N PF02383.18 OAJ17484.1 - 1.7e-76 257.6 0.0 2.7e-76 256.9 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAJ17484.1 - 5e-29 100.4 0.0 2.6e-28 98.0 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase Ribul_P_3_epim PF00834.19 OAJ17485.1 - 6.1e-66 221.6 0.0 7.2e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OAJ17485.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.10 OAJ17485.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Hydrolase_4 PF12146.8 OAJ17486.1 - 1.3e-09 37.7 0.1 7.1e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAJ17486.1 - 3.5e-07 30.3 0.6 9.1e-07 28.9 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 OAJ17486.1 - 7e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17486.1 - 8.9e-07 29.7 2.3 1.8e-06 28.7 2.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 OAJ17486.1 - 0.0087 15.6 0.0 0.036 13.5 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 OAJ17486.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain DUF1308 PF07000.11 OAJ17487.1 - 5.6e-06 26.4 0.0 0.0016 18.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) DUF5614 PF18474.1 OAJ17487.1 - 0.0091 15.3 0.0 4.5 6.5 0.0 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5614) Pribosyltran_N PF13793.6 OAJ17488.1 - 8.2e-43 145.0 0.2 3.2e-42 143.1 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ17488.1 - 1e-39 136.5 2.7 3.2e-32 112.0 0.2 2.9 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ17488.1 - 5e-17 61.9 0.9 3.8e-14 52.5 0.6 3.0 3 0 0 3 3 3 2 Phosphoribosyl transferase domain Peptidase_S10 PF00450.22 OAJ17489.1 - 8.2e-112 374.7 0.8 1.1e-111 374.2 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Apolipoprotein PF01442.18 OAJ17489.1 - 0.05 13.5 0.7 0.08 12.8 0.7 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAJ17489.1 - 0.066 13.2 0.8 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ChW PF07538.11 OAJ17489.1 - 0.25 11.3 1.4 0.51 10.3 1.4 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W DUF883 PF05957.13 OAJ17489.1 - 0.36 11.4 1.6 0.84 10.3 1.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FA_hydroxylase PF04116.13 OAJ17490.1 - 3.9e-19 69.3 6.0 3.9e-19 69.3 6.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NmrA PF05368.13 OAJ17491.1 - 4.4e-37 127.9 0.2 5.2e-37 127.6 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ17491.1 - 4.7e-17 62.5 0.1 7.3e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAJ17491.1 - 0.0019 17.3 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ17491.1 - 0.03 14.2 0.1 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 KR domain Cys_Met_Meta_PP PF01053.20 OAJ17491.1 - 0.04 12.4 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GDP_Man_Dehyd PF16363.5 OAJ17491.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Pex2_Pex12 PF04757.14 OAJ17503.1 - 9.2e-43 146.4 0.4 1.1e-42 146.1 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAJ17503.1 - 1.5e-06 27.9 0.5 2.2e-06 27.4 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ17503.1 - 0.0092 15.8 0.4 0.015 15.1 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ17503.1 - 0.043 14.1 0.4 0.064 13.6 0.4 1.3 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 OAJ17503.1 - 0.15 12.0 1.0 1 9.3 1.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAJ17503.1 - 0.16 11.9 0.4 0.24 11.3 0.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ17503.1 - 0.34 11.0 1.9 0.59 10.2 1.9 1.4 1 0 0 1 1 1 0 RING-type zinc-finger FdhE PF04216.12 OAJ17503.1 - 0.35 10.7 0.8 0.58 10.0 0.8 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4_4 PF15227.6 OAJ17503.1 - 1.2 9.3 3.0 2.1 8.6 3.0 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LCM PF04072.14 OAJ17504.1 - 1.8e-14 54.1 0.0 5.3e-13 49.3 0.0 2.4 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase Yip1 PF04893.17 OAJ17505.1 - 2e-09 37.4 11.5 4e-09 36.4 11.5 1.5 1 0 0 1 1 1 1 Yip1 domain DUF2070 PF09843.9 OAJ17505.1 - 2 6.6 8.1 2.7 6.2 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Keratin_2_head PF16208.5 OAJ17505.1 - 2.1 8.5 25.3 3.5 7.8 25.3 1.3 1 0 0 1 1 1 0 Keratin type II head DUF1691 PF07950.11 OAJ17506.1 - 1.5e-05 25.6 0.6 1.5e-05 25.6 0.6 3.6 2 2 2 4 4 4 1 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 OAJ17506.1 - 0.00043 20.3 3.1 0.00097 19.2 0.1 2.6 2 1 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4405 PF14358.6 OAJ17506.1 - 0.02 15.4 1.7 0.56 10.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) CwsA PF10814.8 OAJ17506.1 - 0.11 12.6 2.3 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Mito_carr PF00153.27 OAJ17507.1 - 3.9e-53 177.4 7.9 9.8e-19 67.1 0.1 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2423 PF10338.9 OAJ17508.1 - 8.9e-10 38.6 3.6 1.7e-09 37.7 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) UBA PF00627.31 OAJ17509.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Kinesin PF00225.23 OAJ17510.1 - 5.3e-71 239.3 0.0 2.9e-43 148.1 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ17510.1 - 1.6e-09 37.9 0.0 1.6e-05 24.9 0.0 3.3 3 0 0 3 3 3 2 Microtubule binding SUIM_assoc PF16619.5 OAJ17511.1 - 0.0013 18.8 0.4 11 6.2 5.0 3.2 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 Kinesin PF00225.23 OAJ17512.1 - 2.2e-102 342.4 0.0 9.9e-102 340.3 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ17512.1 - 1.6e-24 86.6 0.0 7.7e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Ribosomal_S30AE PF02482.19 OAJ17512.1 - 0.13 13.0 2.1 0.68 10.8 0.0 2.8 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF5098 PF17023.5 OAJ17512.1 - 0.23 10.4 0.9 0.74 8.7 0.0 2.1 2 1 0 3 3 3 0 Domain of unknown function (DUF5098) P4Ha_N PF08336.11 OAJ17512.1 - 0.6 10.1 6.0 3.2 7.8 0.9 3.2 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region KxDL PF10241.9 OAJ17512.1 - 4.7 7.6 6.4 31 4.9 0.2 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein Glyco_hydro_32N PF00251.20 OAJ17513.1 - 1.4e-20 74.1 0.0 2.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ17513.1 - 1.5e-14 54.3 0.0 2.8e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal COesterase PF00135.28 OAJ17514.1 - 5e-87 292.9 0.0 2.1e-86 290.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ17514.1 - 1e-05 25.5 0.0 3.5e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold NTP_transf_9 PF04248.12 OAJ17515.1 - 1.4e-30 105.0 0.5 1.2e-29 102.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF427) CAP_N PF01213.19 OAJ17516.1 - 0.06 12.8 0.4 0.06 12.8 0.4 3.5 3 1 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DAO PF01266.24 OAJ17517.1 - 3.8e-35 122.1 0.1 4.9e-35 121.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ17517.1 - 4.7e-05 23.4 0.1 0.00033 20.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ17517.1 - 0.0013 18.9 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.24 OAJ17517.1 - 0.045 14.2 0.3 0.49 10.8 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CagY_I PF14585.6 OAJ17517.1 - 0.25 11.5 2.9 8.2 6.6 0.0 3.2 3 0 0 3 3 3 0 CagY type 1 repeat Coatomer_E PF04733.14 OAJ17518.1 - 5.7e-45 153.9 7.0 7.2e-45 153.6 7.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_17 PF13431.6 OAJ17518.1 - 0.018 15.4 0.9 2.3 8.8 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Protoglobin PF11563.8 OAJ17518.1 - 0.057 13.3 0.4 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Protoglobin TPR_14 PF13428.6 OAJ17518.1 - 2.4 9.2 19.8 38 5.5 0.3 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17518.1 - 2.5 8.4 16.3 4.3 7.7 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat RunxI PF08504.11 OAJ17519.1 - 0.52 11.0 3.9 4.3 8.1 3.8 2.2 1 1 0 1 1 1 0 Runx inhibition domain DUF4743 PF15916.5 OAJ17520.1 - 3.3e-12 46.4 0.0 1.1e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAJ17520.1 - 9.3e-12 45.1 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pox_RNA_pol PF03293.14 OAJ17520.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Hira PF07569.11 OAJ17521.1 - 6e-33 114.4 0.0 2.1e-31 109.4 0.0 2.5 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 OAJ17521.1 - 2.6e-24 85.0 19.7 6.2e-06 26.9 0.2 7.8 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17521.1 - 7.6e-10 39.0 1.2 0.33 11.3 0.0 5.9 5 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAJ17521.1 - 7.5e-08 32.0 2.8 1.3e-07 31.2 1.2 2.3 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 OAJ17521.1 - 0.081 12.9 2.2 13 5.8 0.2 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat UCR_TM PF02921.14 OAJ17522.1 - 4.1e-12 46.4 3.1 1.9e-11 44.2 3.1 2.1 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 OAJ17522.1 - 8.4e-11 41.7 0.0 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain tRNA-synt_1 PF00133.22 OAJ17524.1 - 2.3e-151 505.0 0.0 3.4e-151 504.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ17524.1 - 5.3e-24 84.9 0.0 1e-23 84.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ17524.1 - 1.3e-18 67.0 0.2 1.4e-09 37.2 0.0 4.5 4 0 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ17524.1 - 0.00082 18.9 0.0 0.0024 17.4 0.0 1.7 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ17524.1 - 0.076 12.3 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 OAJ17524.1 - 0.14 12.0 8.1 0.8 9.6 8.5 2.1 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS Mpv17_PMP22 PF04117.12 OAJ17525.1 - 4.9e-24 84.3 4.4 1.1e-23 83.2 4.4 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sars6 PF12133.8 OAJ17525.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus PH PF00169.29 OAJ17526.1 - 8.5e-39 132.3 3.1 1.8e-20 73.4 0.3 3.2 3 0 0 3 3 3 3 PH domain PH_3 PF14593.6 OAJ17526.1 - 1.8e-16 60.1 0.9 1.3e-07 31.6 0.3 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 OAJ17526.1 - 7e-13 48.9 11.6 8.6e-06 26.1 6.4 4.1 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 OAJ17526.1 - 1.3e-11 44.6 4.8 7e-07 29.4 0.9 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 OAJ17526.1 - 6.1e-08 33.1 2.8 0.00033 21.0 0.7 4.1 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.7 OAJ17526.1 - 0.049 13.7 4.8 5.6 7.1 0.5 3.3 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Myosin_TH1 PF06017.13 OAJ17526.1 - 0.11 12.2 0.0 15 5.2 0.0 3.1 4 0 0 4 4 4 0 Unconventional myosin tail, actin- and lipid-binding PH_2 PF08458.10 OAJ17526.1 - 0.19 12.1 0.4 13 6.2 0.0 2.6 3 0 0 3 3 3 0 Plant pleckstrin homology-like region PH_4 PF15404.6 OAJ17526.1 - 0.88 9.3 8.1 0.99 9.2 0.1 3.4 4 0 0 4 4 4 0 Pleckstrin homology domain Got1 PF04178.12 OAJ17527.1 - 5.6e-18 65.4 15.4 7e-18 65.1 15.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Thioredoxin PF00085.20 OAJ17528.1 - 7.7e-30 102.9 0.0 9e-30 102.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ17528.1 - 1.6e-07 31.7 0.2 5.6e-07 30.0 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ17528.1 - 7e-05 22.7 0.0 8.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ17528.1 - 9.9e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 OAJ17528.1 - 0.0001 22.6 0.0 0.00016 21.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAJ17528.1 - 0.00014 21.3 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OAJ17528.1 - 0.00029 21.0 0.0 0.00047 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 OAJ17528.1 - 0.00054 19.9 0.0 0.00058 19.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OAJ17528.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 OAJ17528.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 OAJ17528.1 - 0.15 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain JmjC PF02373.22 OAJ17529.1 - 5e-18 65.6 0.0 2.9e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAJ17529.1 - 1.4e-17 64.2 0.0 2.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain CoA_transf_3 PF02515.17 OAJ17543.1 - 1.1e-126 422.9 0.0 1.3e-126 422.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Abhydrolase_1 PF00561.20 OAJ17544.1 - 9.6e-08 32.0 0.0 5.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ17544.1 - 0.052 12.8 0.0 9.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 OAJ17545.1 - 1.1e-08 35.1 12.9 0.001 19.4 2.1 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ17545.1 - 3.9e-08 33.4 15.1 6.4e-05 23.2 4.0 4.3 3 0 0 3 3 3 3 Zinc-finger double domain Myb_DNA-binding PF00249.31 OAJ17548.1 - 7.9e-17 61.2 0.2 2e-06 27.9 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ17548.1 - 9.8e-14 51.4 0.0 0.00023 21.3 0.0 3.6 3 1 1 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ17548.1 - 0.003 17.7 0.2 2 8.6 0.1 3.2 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 OAJ17548.1 - 0.081 12.8 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Lactonase PF10282.9 OAJ17550.1 - 7.1e-17 61.7 0.0 1.6e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller RT_RNaseH PF17917.1 OAJ17551.1 - 3.6e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ17551.1 - 8.5e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Synaptobrevin PF00957.21 OAJ17552.1 - 2.1e-32 110.8 1.6 2.3e-32 110.6 1.6 1.0 1 0 0 1 1 1 1 Synaptobrevin Rhamno_transf PF11316.8 OAJ17552.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase DUF948 PF06103.11 OAJ17552.1 - 0.31 11.3 6.1 0.72 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prenylcys_lyase PF07156.14 OAJ17553.1 - 2.9e-65 220.7 0.0 2.2e-63 214.6 0.0 2.7 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OAJ17553.1 - 1.3e-11 44.6 0.0 4.2e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ17553.1 - 1.2e-06 28.3 0.1 3.5e-06 26.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ17553.1 - 1.5e-05 25.0 0.1 0.00035 20.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAJ17553.1 - 2.7e-05 23.7 0.0 5.4e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAJ17553.1 - 0.00016 21.0 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ17553.1 - 0.0013 17.9 2.2 0.0024 17.0 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAJ17553.1 - 0.0023 17.2 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAJ17553.1 - 0.005 16.2 0.2 0.0074 15.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAJ17553.1 - 0.0056 15.6 0.1 0.0083 15.0 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 OAJ17553.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAJ17553.1 - 0.015 14.4 0.8 0.26 10.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A TAFII28 PF04719.14 OAJ17553.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Pyr_redox PF00070.27 OAJ17553.1 - 0.051 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAJ17553.1 - 0.073 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 OAJ17553.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) E1_DerP2_DerF2 PF02221.15 OAJ17554.1 - 5.3e-28 98.1 0.0 6.7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 ML domain MOZ_SAS PF01853.18 OAJ17555.1 - 3e-56 189.9 0.1 6.8e-56 188.7 0.1 1.5 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 OAJ17555.1 - 4.2e-13 48.7 6.5 2.5e-07 30.2 0.5 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 OAJ17555.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EF-hand_7 PF13499.6 OAJ17556.1 - 4.1e-25 88.0 5.3 2.4e-15 56.7 1.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 OAJ17556.1 - 4.8e-25 85.2 8.1 2.5e-08 32.9 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 OAJ17556.1 - 2.2e-21 73.9 4.0 1.5e-06 27.7 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ17556.1 - 2e-12 46.8 5.3 0.00034 20.4 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ17556.1 - 1.1e-10 40.5 11.6 0.00013 21.3 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 OAJ17556.1 - 8.9e-10 38.5 6.4 0.00092 19.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ17556.1 - 5.4e-06 26.6 0.9 0.00032 21.0 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ17556.1 - 0.026 14.9 2.8 1.5 9.1 0.2 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OAJ17556.1 - 1.1 9.2 4.3 19 5.1 0.1 3.2 2 1 1 3 3 3 0 Caleosin related protein Use1 PF09753.9 OAJ17557.1 - 1.4e-08 34.8 0.0 1.6e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 YTH PF04146.15 OAJ17558.1 - 1.7e-51 174.5 1.1 1.7e-51 174.5 1.1 3.6 3 3 0 3 3 3 1 YT521-B-like domain RRM_1 PF00076.22 OAJ17558.1 - 0.0013 18.5 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Galactosyl_T PF01762.21 OAJ17559.1 - 1.6e-09 37.9 0.4 8.9e-05 22.4 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase DUF726 PF05277.12 OAJ17560.1 - 1.9e-40 138.9 10.2 3.6e-31 108.4 4.2 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF726) Ser_hydrolase PF06821.13 OAJ17560.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Peptidase_S37 PF05576.11 OAJ17560.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 LIDHydrolase PF10230.9 OAJ17560.1 - 0.21 11.1 0.0 0.47 10.0 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAJ17560.1 - 0.23 12.0 0.1 0.23 12.0 0.1 2.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family CarS-like PF01864.17 OAJ17560.1 - 5.9 6.8 8.3 34 4.4 0.1 2.5 2 0 0 2 2 2 0 CDP-archaeol synthase zf-C2H2 PF00096.26 OAJ17561.1 - 1e-07 32.0 9.2 0.00077 19.8 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ17561.1 - 0.002 18.5 3.6 0.002 18.5 3.6 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ17561.1 - 0.0087 16.8 14.6 0.11 13.5 1.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger Methyltransf_PK PF05891.12 OAJ17562.1 - 3.5e-49 167.3 0.0 1.1e-15 57.8 0.0 4.2 4 0 0 4 4 4 4 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OAJ17562.1 - 0.00051 20.7 0.1 1.3 9.8 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ17562.1 - 0.00087 20.0 0.0 1 10.1 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ17562.1 - 0.002 18.0 0.0 0.0094 15.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MRVI1 PF05781.12 OAJ17562.1 - 0.033 12.9 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 MRVI1 protein Methyltransf_11 PF08241.12 OAJ17562.1 - 0.068 13.8 0.0 21 5.8 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.14 OAJ17562.1 - 1.3 7.2 3.2 1.1 7.5 0.3 1.9 2 0 0 2 2 2 0 CDC45-like protein rve PF00665.26 OAJ17568.1 - 0.014 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Sec66 PF09802.9 OAJ17586.1 - 4.3e-54 182.8 0.1 5.8e-54 182.4 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 B56 PF01603.20 OAJ17587.1 - 6.7e-192 638.0 2.5 7.9e-192 637.8 2.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sld5 PF05916.11 OAJ17588.1 - 0.00033 21.1 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein DMA PF03474.14 OAJ17588.1 - 0.041 13.5 0.3 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 DMRTA motif Peptidase_M24_C PF16188.5 OAJ17588.1 - 0.063 13.3 0.1 0.91 9.6 0.0 2.4 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 DMRL_synthase PF00885.19 OAJ17589.1 - 3.7e-51 172.7 0.0 4.9e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.10 OAJ17589.1 - 0.00059 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding F-box-like PF12937.7 OAJ17590.1 - 2.1e-07 30.7 1.1 1.2e-06 28.3 0.7 2.4 2 0 0 2 2 2 1 F-box-like Mga PF05043.13 OAJ17590.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Mga helix-turn-helix domain F-box PF00646.33 OAJ17590.1 - 6.3 6.8 5.3 6.4 6.8 2.1 2.6 2 1 0 2 2 2 0 F-box domain Urb2 PF10441.9 OAJ17591.1 - 2.7e-40 138.5 2.2 5.5e-40 137.5 0.0 2.8 3 1 1 4 4 4 1 Urb2/Npa2 family HEAT PF02985.22 OAJ17591.1 - 0.079 13.3 0.3 3.5 8.1 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat DnaJ PF00226.31 OAJ17594.1 - 1.5e-15 57.1 1.0 3.2e-15 56.0 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Transcrip_reg PF01709.20 OAJ17595.1 - 3.2e-61 206.8 0.0 2.1e-60 204.2 0.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator Spore_III_AB PF09548.10 OAJ17595.1 - 0.023 14.8 0.1 0.064 13.4 0.1 1.8 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HTH_31 PF13560.6 OAJ17595.1 - 0.044 14.1 0.2 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TIP41 PF04176.13 OAJ17596.1 - 1.4e-47 161.4 0.0 4.9e-45 153.1 0.0 3.4 2 1 0 2 2 2 2 TIP41-like family Hat1_N PF10394.9 OAJ17598.1 - 5.1e-41 140.6 0.0 1.4e-40 139.2 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus DUF1330 PF07045.11 OAJ17598.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1330) Acetyltransf_10 PF13673.7 OAJ17598.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ17598.1 - 0.011 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1279 PF06916.13 OAJ17599.1 - 2.1e-17 63.5 0.0 1.1e-16 61.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_S8 PF00082.22 OAJ17600.1 - 1.5e-45 155.7 0.0 2.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ17600.1 - 3.8e-07 30.8 0.0 6.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Fn3-like domain MFS_1 PF07690.16 OAJ17601.1 - 1.5e-17 63.6 47.8 1.5e-17 63.6 47.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ17601.1 - 0.0078 14.6 0.0 0.0078 14.6 0.0 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATP1G1_PLM_MAT8 PF02038.16 OAJ17601.1 - 5.8 6.4 8.5 0.77 9.2 0.9 3.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family ECH_2 PF16113.5 OAJ17602.1 - 8.2e-78 262.2 0.0 2.3e-74 250.9 0.0 3.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAJ17602.1 - 6.1e-19 68.3 0.0 3e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 OAJ17603.1 - 2.9e-40 138.3 0.0 4.4e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17603.1 - 3.4e-21 75.7 0.0 5.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ17603.1 - 1.4e-06 27.9 0.0 0.0003 20.2 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAJ17603.1 - 0.053 13.4 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PRELI PF04707.14 OAJ17604.1 - 1.7e-18 66.9 0.2 2.7e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 PRELI-like family SelP_N PF04592.14 OAJ17605.1 - 1.6 8.1 11.4 3.4 7.0 11.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CMAS PF02353.20 OAJ17606.1 - 3.6e-33 115.0 0.3 1.6e-32 112.9 0.3 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ17606.1 - 7.8e-13 49.0 0.0 1.8e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ17606.1 - 7e-12 45.8 0.0 1.8e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ17606.1 - 6.1e-08 32.6 0.0 2.2e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ17606.1 - 2.8e-06 27.3 0.0 6.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ17606.1 - 1.2e-05 25.9 0.0 3.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ17606.1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAJ17606.1 - 0.013 14.9 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.14 OAJ17606.1 - 0.014 14.9 0.0 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 OAJ17606.1 - 0.042 13.1 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DOT1 PF08123.13 OAJ17606.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 SWIB PF02201.18 OAJ17607.1 - 1.1e-21 76.5 0.1 4.4e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain UPF0160 PF03690.13 OAJ17608.1 - 1.6e-131 438.7 0.0 2.3e-131 438.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.10 OAJ17608.1 - 2e-08 34.6 0.0 3.3e-07 30.6 0.0 2.4 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAJ17608.1 - 1.6e-06 28.3 0.0 7.8e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Ydr279p protein triple barrel domain DUF4841 PF16129.5 OAJ17608.1 - 0.0074 16.5 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4841) WD40 PF00400.32 OAJ17609.1 - 1.4e-32 111.2 16.8 2.5e-05 24.9 0.0 10.6 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 OAJ17609.1 - 7.5e-18 64.8 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAJ17609.1 - 7.3e-13 48.6 0.0 0.65 10.3 0.0 8.1 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ17609.1 - 0.00018 20.3 0.1 0.6 8.7 0.0 4.1 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAJ17609.1 - 0.0013 17.8 1.3 25 3.7 0.1 4.9 3 3 3 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 OAJ17609.1 - 0.0014 18.5 0.4 0.02 14.7 0.0 2.8 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.16 OAJ17609.1 - 0.0023 16.5 0.1 1.3 7.5 0.0 3.5 3 1 0 3 3 3 2 Cytochrome D1 heme domain DUF1513 PF07433.11 OAJ17609.1 - 0.021 13.9 0.1 0.81 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) PQQ PF01011.21 OAJ17609.1 - 0.12 12.4 2.6 2.6 8.1 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat PD40 PF07676.12 OAJ17609.1 - 0.28 11.2 3.1 32 4.6 0.0 5.0 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat COX14 PF14880.6 OAJ17611.1 - 0.0043 16.9 0.2 0.0063 16.3 0.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly zf-U1 PF06220.12 OAJ17612.1 - 7.6e-15 54.4 3.7 1.1e-14 53.9 3.7 1.2 1 0 0 1 1 1 1 U1 zinc finger Forkhead PF00250.18 OAJ17626.1 - 4.3e-11 42.9 0.1 8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain DUF974 PF06159.13 OAJ17628.1 - 2.6e-44 151.9 0.0 4.5e-38 131.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF974) Med26 PF08711.11 OAJ17629.1 - 9.9e-10 38.3 0.1 4.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain SDA1 PF05285.12 OAJ17630.1 - 0.45 9.9 3.9 0.62 9.4 3.9 1.2 1 0 0 1 1 1 0 SDA1 TauD PF02668.16 OAJ17631.1 - 2.6e-42 145.5 0.1 4.2e-42 144.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2462 PF09495.10 OAJ17633.1 - 3e-17 63.1 11.2 3e-17 63.1 11.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) DUF2868 PF11067.8 OAJ17633.1 - 0.39 10.2 2.9 0.44 10.0 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) AMP-binding PF00501.28 OAJ17634.1 - 5.3e-80 269.1 0.0 1.1e-79 268.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ17634.1 - 0.049 14.6 0.1 0.11 13.4 0.1 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF2722 PF10846.8 OAJ17635.1 - 1.2e-06 27.7 13.8 1.5e-05 24.2 6.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Integrase_H2C2 PF17921.1 OAJ17635.1 - 1.9e-05 24.7 0.1 1.9e-05 24.7 0.1 2.0 2 0 0 2 2 1 1 Integrase zinc binding domain DDHD PF02862.17 OAJ17635.1 - 0.00042 20.5 2.4 0.0071 16.5 0.4 2.2 2 0 0 2 2 2 1 DDHD domain SUIM_assoc PF16619.5 OAJ17635.1 - 0.0012 18.8 0.1 0.0012 18.8 0.1 3.7 2 2 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 EPL1 PF10513.9 OAJ17635.1 - 0.09 13.2 12.1 0.72 10.2 6.6 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM193_C PF15914.5 OAJ17635.1 - 0.23 11.3 0.4 0.46 10.3 0.4 1.4 1 0 0 1 1 1 0 FAM193 family C-terminal DUF3371 PF11851.8 OAJ17635.1 - 0.25 12.5 20.8 0.55 11.3 10.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Spt20 PF12090.8 OAJ17635.1 - 0.36 10.4 42.6 0.49 10.0 27.7 2.2 2 0 0 2 2 2 0 Spt20 family Utp21 PF04192.12 OAJ17635.1 - 0.72 9.3 11.6 3.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain E_Pc_C PF06752.12 OAJ17635.1 - 0.76 9.8 46.3 0.17 12.0 4.9 2.9 2 1 0 2 2 2 0 Enhancer of Polycomb C-terminus TFIIA PF03153.13 OAJ17635.1 - 0.9 9.5 41.7 0.99 9.3 25.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 OAJ17635.1 - 1.2 9.5 9.1 0.31 11.4 4.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.16 OAJ17635.1 - 1.8 8.6 11.9 9 6.3 6.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BORG_CEP PF14957.6 OAJ17635.1 - 2.5 9.3 11.7 0.97 10.6 2.9 3.1 3 0 0 3 3 3 0 Cdc42 effector CagX PF03524.15 OAJ17635.1 - 2.9 7.6 9.2 7.3 6.3 4.1 2.9 3 0 0 3 3 3 0 Conjugal transfer protein LIM_bind PF01803.16 OAJ17635.1 - 4.9 6.6 15.1 0.18 11.3 7.2 2.1 2 0 0 2 2 2 0 LIM-domain binding protein CPSF100_C PF13299.6 OAJ17635.1 - 6.2 7.0 10.6 7 6.8 5.9 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PAT1 PF09770.9 OAJ17635.1 - 7.7 4.6 25.3 0.14 10.4 13.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 OAJ17635.1 - 9.3 4.9 13.9 0.69 8.6 6.6 2.0 2 0 0 2 2 2 0 Presenilin DUF3391 PF11871.8 OAJ17635.1 - 9.7 6.7 12.6 9 6.8 5.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) adh_short_C2 PF13561.6 OAJ17636.1 - 6.2e-46 156.9 0.0 7e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ17636.1 - 3.2e-36 124.6 0.0 3.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ17636.1 - 1.7e-09 37.9 0.1 2.1e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAJ17636.1 - 0.0021 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAJ17636.1 - 0.15 11.5 0.0 0.74 9.2 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Striatin PF08232.12 OAJ17637.1 - 5e-47 160.4 2.5 5e-47 160.4 2.5 5.2 3 2 0 3 3 3 1 Striatin family WD40 PF00400.32 OAJ17637.1 - 2e-26 91.7 11.0 1.8e-05 25.4 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17637.1 - 1.1e-05 25.6 0.0 0.045 14.0 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NAC PF01849.18 OAJ17638.1 - 5.1e-21 74.4 0.0 1.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 NAC domain Med15 PF09606.10 OAJ17638.1 - 0.0033 16.2 4.0 0.0035 16.1 4.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_16 PF10294.9 OAJ17639.1 - 5.7e-21 75.0 0.0 5.7e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase R3H PF01424.22 OAJ17640.1 - 6.7e-11 42.0 0.2 1.6e-10 40.8 0.2 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAJ17640.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF4 PF05236.14 OAJ17640.1 - 0.23 11.2 0.1 0.23 11.2 0.1 3.2 3 0 0 3 3 3 0 Transcription initiation factor TFIID component TAF4 family OPT PF03169.15 OAJ17641.1 - 1.3e-164 549.2 54.5 1.6e-164 549.0 54.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pro_isomerase PF00160.21 OAJ17642.1 - 1e-15 58.3 0.0 1.4e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD eIF-5_eIF-2B PF01873.17 OAJ17643.1 - 3.4e-39 133.3 0.0 7.7e-39 132.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 OAJ17643.1 - 3e-17 62.5 0.4 8.4e-17 61.1 0.1 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Apt1 PF10351.9 OAJ17645.1 - 0.071 12.0 3.4 0.06 12.2 3.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SpoIIIAH PF12685.7 OAJ17645.1 - 0.28 11.0 2.5 0.4 10.5 2.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Ndc1_Nup PF09531.10 OAJ17645.1 - 1.4 7.5 4.7 1.3 7.6 4.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_5_C PF18564.1 OAJ17647.1 - 2.1e-20 73.1 0.0 4.5e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ17647.1 - 4.7e-09 36.1 0.0 1.2e-05 24.9 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) DUF2897 PF11446.8 OAJ17647.1 - 7.2 6.6 6.2 0.76 9.7 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) CDO_I PF05995.12 OAJ17648.1 - 0.00033 20.0 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAJ17648.1 - 0.0011 18.5 2.4 0.016 14.7 2.4 2.2 1 1 0 1 1 1 1 PCO_ADO DUF772 PF05598.11 OAJ17648.1 - 0.089 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Transposase domain (DUF772) rve PF00665.26 OAJ17660.1 - 0.00053 20.2 0.3 0.0015 18.7 0.1 1.9 2 1 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 OAJ17660.1 - 0.022 14.6 0.2 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain RRM_Rrp7 PF17799.1 OAJ17660.1 - 0.098 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain HTH_Tnp_4 PF13613.6 OAJ17660.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease PHD PF00628.29 OAJ17661.1 - 4.5e-05 23.2 8.0 9.2e-05 22.3 8.0 1.5 1 0 0 1 1 1 1 PHD-finger XAF1_C PF18608.1 OAJ17661.1 - 0.27 10.8 2.4 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain WD40 PF00400.32 OAJ17662.1 - 3.8 8.5 15.9 3.8 8.5 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Aconitase PF00330.20 OAJ17663.1 - 3.7e-160 533.9 0.1 4.6e-160 533.6 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ17663.1 - 9.8e-43 145.6 0.0 2e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CsbD PF05532.12 OAJ17663.1 - 0.14 12.1 2.2 0.29 11.1 2.2 1.6 1 0 0 1 1 1 0 CsbD-like Peptidase_C48 PF02902.19 OAJ17664.1 - 7e-08 32.6 0.4 4.5e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DEAD PF00270.29 OAJ17665.1 - 6.3e-37 127.0 0.0 1.2e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ17665.1 - 7.9e-19 68.1 0.0 2.1e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ17665.1 - 3e-14 53.0 0.0 5.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ17665.1 - 1.3e-06 28.6 0.0 2.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SR-25 PF10500.9 OAJ17665.1 - 0.00094 18.9 14.4 0.00094 18.9 14.4 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4692 PF15763.5 OAJ17665.1 - 0.022 15.2 6.9 0.049 14.1 6.9 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SBF_like PF13593.6 OAJ17665.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 OAJ17665.1 - 0.05 13.9 0.7 0.38 11.0 0.7 2.4 1 1 0 1 1 1 0 AAA domain CSRNP_N PF16019.5 OAJ17665.1 - 0.78 9.6 6.7 1.5 8.7 6.7 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CCDC106 PF15794.5 OAJ17665.1 - 3.1 7.5 14.2 6.4 6.4 14.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BAR_3 PF16746.5 OAJ17666.1 - 0.0026 17.5 0.1 0.51 10.0 0.1 2.4 2 0 0 2 2 2 2 BAR domain of APPL family SesA PF17107.5 OAJ17666.1 - 0.026 14.7 3.8 0.03 14.5 0.2 2.6 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases zf-TRAF PF02176.18 OAJ17667.1 - 0.64 10.8 4.6 0.77 10.5 1.6 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger Retrotran_gag_2 PF14223.6 OAJ17669.1 - 5.7e-19 68.2 0.2 7.3e-19 67.8 0.2 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NDC10_II PF16787.5 OAJ17670.1 - 3.6e-20 72.3 0.0 4.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ17670.1 - 1.4e-07 31.7 0.1 2.5e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Dimer_Tnp_hAT PF05699.14 OAJ17671.1 - 2.3e-08 33.7 0.0 9.5e-08 31.7 0.0 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RTC_insert PF05189.13 OAJ17671.1 - 0.05 14.1 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4413 PF14372.6 OAJ17671.1 - 0.15 12.4 0.1 0.47 10.8 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) NDC10_II PF16787.5 OAJ17672.1 - 9.9e-15 54.4 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RT_RNaseH PF17917.1 OAJ17673.1 - 7.8e-35 119.3 0.0 1.4e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ17673.1 - 3e-27 94.6 0.0 5.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ17673.1 - 1.1e-21 77.4 0.1 2.6e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ17673.1 - 5e-18 64.9 0.4 1.1e-17 63.8 0.4 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ17673.1 - 9e-11 42.0 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ17673.1 - 0.00021 21.4 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger CBFD_NFYB_HMF PF00808.23 OAJ17674.1 - 1.3e-06 28.6 0.5 4.4e-06 26.9 0.2 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAJ17674.1 - 0.00048 19.6 22.8 0.00054 19.4 22.8 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 OAJ17674.1 - 0.0012 18.9 14.5 0.0013 18.8 14.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 OAJ17674.1 - 0.011 15.1 21.9 0.014 14.8 21.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S49_N PF08496.10 OAJ17674.1 - 0.015 15.3 4.4 0.015 15.3 4.4 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Histone PF00125.24 OAJ17674.1 - 0.15 12.4 0.1 0.15 12.4 0.1 2.6 2 1 0 2 2 1 0 Core histone H2A/H2B/H3/H4 SDA1 PF05285.12 OAJ17674.1 - 0.35 10.2 33.2 0.45 9.9 33.2 1.1 1 0 0 1 1 1 0 SDA1 MDM1 PF15501.6 OAJ17674.1 - 0.61 9.2 16.8 0.74 8.9 16.8 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 BAF1_ABF1 PF04684.13 OAJ17674.1 - 1.7 7.6 12.9 2.3 7.2 12.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Sec62 PF03839.16 OAJ17674.1 - 2.8 7.4 9.3 4.9 6.6 9.3 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 eIF-3c_N PF05470.12 OAJ17674.1 - 3.2 6.0 12.9 4.3 5.5 12.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spore_coat_CotO PF14153.6 OAJ17674.1 - 3.9 7.4 20.2 5.6 6.8 20.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ctr PF04145.15 OAJ17675.1 - 9e-17 62.1 0.2 7.2e-16 59.1 0.2 2.0 1 1 0 1 1 1 1 Ctr copper transporter family GRAB PF10375.9 OAJ17676.1 - 7.3e-06 25.7 1.3 7.3e-06 25.7 1.3 2.8 3 0 0 3 3 3 1 GRIP-related Arf-binding domain Macoilin PF09726.9 OAJ17676.1 - 0.0031 16.2 8.6 0.0031 16.2 8.6 3.7 3 1 1 4 4 4 1 Macoilin family DUF4407 PF14362.6 OAJ17676.1 - 0.052 12.9 41.1 0.76 9.1 27.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 OAJ17676.1 - 0.22 11.3 16.0 0.51 10.1 0.1 4.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF1319 PF07028.11 OAJ17676.1 - 0.3 11.3 3.3 0.53 10.5 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) DivIC PF04977.15 OAJ17676.1 - 1.3 8.9 32.8 0.43 10.4 1.3 5.5 2 1 3 5 5 5 0 Septum formation initiator NPV_P10 PF05531.12 OAJ17676.1 - 3.1 8.3 9.6 7.1 7.2 0.9 3.6 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein BBP1_C PF15272.6 OAJ17676.1 - 5.8 6.7 24.2 0.11 12.3 15.8 2.2 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal GOLGA2L5 PF15070.6 OAJ17676.1 - 9.1 4.8 36.0 2.7 6.5 11.8 2.1 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 RRM_1 PF00076.22 OAJ17677.1 - 6.1e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 OAJ17677.1 - 2e-05 24.4 0.2 4.1e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain SPATIAL PF15256.6 OAJ17677.1 - 0.1 12.9 0.3 0.29 11.4 0.3 1.8 1 0 0 1 1 1 0 SPATIAL MEIOC PF15189.6 OAJ17677.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC INCENP_ARK-bind PF03941.15 OAJ17678.1 - 2.5e-07 30.5 0.7 2.5e-07 30.5 0.7 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region DNA_primase_S PF01896.19 OAJ17679.1 - 1e-53 182.0 0.0 2.7e-53 180.6 0.0 1.7 1 1 0 1 1 1 1 DNA primase small subunit Phage_portal PF04860.12 OAJ17679.1 - 0.19 10.9 0.0 0.44 9.7 0.0 1.5 1 0 0 1 1 1 0 Phage portal protein RRM_1 PF00076.22 OAJ17681.1 - 4.9e-25 87.1 0.0 6e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S19e PF01090.19 OAJ17697.1 - 1.2e-53 180.5 0.0 1.4e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SDA1 PF05285.12 OAJ17697.1 - 0.0074 15.7 5.3 0.0086 15.5 5.3 1.1 1 0 0 1 1 1 1 SDA1 RNA_pol_3_Rpc31 PF11705.8 OAJ17697.1 - 0.022 15.0 9.0 0.026 14.8 9.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 OAJ17697.1 - 0.037 13.8 10.0 0.048 13.4 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 OAJ17697.1 - 0.09 12.8 4.0 0.11 12.6 4.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 OAJ17697.1 - 0.57 8.4 5.2 0.6 8.3 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ17697.1 - 3.3 5.8 9.4 3.7 5.6 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 OAJ17697.1 - 9.8 6.6 17.4 19 5.7 17.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFCD_C PF12612.8 OAJ17698.1 - 3.7e-35 121.5 0.0 3.9e-34 118.1 0.0 2.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal FeoB_C PF07664.12 OAJ17698.1 - 0.18 11.5 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Adaptin_N PF01602.20 OAJ17699.1 - 0.0031 16.1 0.7 0.24 9.9 0.1 3.2 3 1 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.22 OAJ17699.1 - 0.0084 16.3 0.1 0.0084 16.3 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 OAJ17699.1 - 0.012 14.8 5.0 0.014 14.5 0.0 2.9 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 OAJ17699.1 - 0.013 15.7 0.1 2.3 8.4 0.0 2.9 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OAJ17699.1 - 0.017 15.2 0.1 0.76 9.8 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAJ17699.1 - 0.029 15.0 0.0 0.26 11.9 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 OAJ17699.1 - 0.037 13.8 0.0 0.18 11.6 0.0 2.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 OAJ17699.1 - 0.049 14.2 0.0 0.049 14.2 0.0 5.6 4 1 1 5 5 5 0 HEAT-like repeat B56 PF01603.20 OAJ17699.1 - 0.2 10.6 0.1 1 8.3 0.0 2.1 3 0 0 3 3 3 0 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT_2 PF13646.6 OAJ17699.1 - 1.5 9.2 11.8 1.3 9.5 0.0 4.9 4 2 1 5 5 5 0 HEAT repeats Nefa_Nip30_N PF10187.9 OAJ17700.1 - 3.8e-27 94.7 10.9 6.3e-27 94.0 10.9 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TPX2 PF06886.11 OAJ17700.1 - 8.2 6.7 17.7 0.91 9.8 5.7 3.2 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) Ribosomal_L27A PF00828.19 OAJ17701.1 - 9.3e-23 81.3 0.1 1.3e-22 80.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GPP34 PF05719.11 OAJ17702.1 - 1.6e-64 217.7 0.0 2.2e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M24 PF00557.24 OAJ17703.1 - 9.5e-13 48.3 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S7 PF00177.21 OAJ17705.1 - 1.6e-29 102.5 0.0 2.3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAF PF11250.8 OAJ17705.1 - 0.54 10.5 2.5 19 5.6 0.2 2.5 2 0 0 2 2 2 0 Fantastic Four meristem regulator HLH PF00010.26 OAJ17706.1 - 6.4e-15 54.8 0.3 1e-14 54.2 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5134 PF17197.4 OAJ17706.1 - 0.0068 16.3 2.7 0.092 12.6 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5134) SelP_N PF04592.14 OAJ17706.1 - 3.8 6.8 7.7 7.3 5.9 7.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HTH_9 PF08221.11 OAJ17707.1 - 4.4e-21 74.7 0.7 1.9e-07 31.1 0.0 4.5 4 0 0 4 4 4 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 OAJ17707.1 - 7.3e-10 39.0 0.0 1.7e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 OAJ17707.1 - 4.1e-06 26.6 0.0 0.00059 19.7 0.0 2.7 3 0 0 3 3 3 2 TFIIE alpha subunit SMC_N PF02463.19 OAJ17708.1 - 3.7e-61 206.4 0.0 1.6e-60 204.3 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ17708.1 - 3.7e-28 98.2 2.0 2.3e-27 95.6 0.1 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAJ17708.1 - 7.9e-17 62.0 3.0 6.2e-08 32.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ17708.1 - 1.1e-08 35.2 9.3 1.1e-08 35.2 9.3 4.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 OAJ17708.1 - 2.4e-08 33.6 0.2 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ17708.1 - 0.00011 22.8 36.0 0.00011 22.8 36.0 7.1 3 2 2 5 5 5 1 AAA domain SbcCD_C PF13558.6 OAJ17708.1 - 0.00064 19.9 0.7 0.006 16.8 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.11 OAJ17708.1 - 0.007 16.6 7.7 0.007 16.6 7.7 7.7 6 1 2 8 8 8 3 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 OAJ17708.1 - 0.076 13.5 0.0 0.076 13.5 0.0 6.3 4 3 0 4 4 4 0 ABC transporter GTP_EFTU PF00009.27 OAJ17709.1 - 1.3e-43 148.8 0.0 2.1e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ17709.1 - 1.4e-12 47.9 0.0 4.3e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 OAJ17709.1 - 2.9e-10 40.3 0.8 9.5e-10 38.6 0.8 1.9 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 OAJ17709.1 - 2.7e-08 33.9 0.0 1.1e-06 28.7 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAJ17709.1 - 4e-06 27.1 0.2 1e-05 25.8 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 OAJ17709.1 - 0.0045 16.4 0.0 2.2 7.7 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 OAJ17709.1 - 0.1 12.5 1.6 0.16 11.9 0.4 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 cobW PF02492.19 OAJ17709.1 - 0.16 11.6 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cdh1_DBD_1 PF18196.1 OAJ17709.1 - 0.59 10.5 3.5 0.41 11.0 0.2 2.3 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Rhodanese PF00581.20 OAJ17710.1 - 3.4e-15 56.5 0.0 7.4e-08 32.9 0.0 3.3 2 2 0 2 2 2 2 Rhodanese-like domain ThiC-associated PF13667.6 OAJ17710.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 ThiC-associated domain RNA_pol_Rbc25 PF08292.12 OAJ17711.1 - 1.8e-28 99.4 0.0 8e-24 84.3 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAJ17711.1 - 1.4e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ17711.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain DUF3510 PF12022.8 OAJ17713.1 - 3e-11 43.8 0.0 1.2e-10 41.9 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 OAJ17713.1 - 2e-07 31.1 4.2 0.00035 20.7 0.0 3.0 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OAJ17713.1 - 0.2 11.9 1.6 39 4.6 0.2 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Hemerythrin PF01814.23 OAJ17713.1 - 8.7 7.0 7.6 1.6 9.4 0.6 3.3 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain Pkinase PF00069.25 OAJ17714.1 - 1.4e-27 96.7 0.0 8.7e-22 77.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17714.1 - 1.3e-11 44.3 0.0 2.8e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_14 PF13428.6 OAJ17714.1 - 0.1 13.4 2.3 2.4 9.2 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AIRC PF00731.20 OAJ17715.1 - 3.8e-57 192.0 0.8 9.2e-57 190.8 0.8 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 OAJ17715.1 - 1.9e-50 170.8 0.1 7.6e-27 94.0 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain PurK_C PF17769.1 OAJ17715.1 - 7.1e-17 60.8 0.0 1.6e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 OAJ17715.1 - 0.0029 17.0 0.0 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAJ17715.1 - 0.0053 16.7 0.2 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpR_N PF06506.11 OAJ17715.1 - 0.0064 16.1 1.7 0.047 13.3 0.0 2.9 4 0 0 4 4 4 1 Propionate catabolism activator Dala_Dala_lig_C PF07478.13 OAJ17715.1 - 0.035 13.6 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus SesA PF17107.5 OAJ17715.1 - 0.072 13.3 0.3 0.2 11.9 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Peptidase_M35 PF02102.15 OAJ17715.1 - 0.073 11.9 3.1 0.14 11.0 3.1 1.4 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Ribosomal_S2 PF00318.20 OAJ17716.1 - 2.7e-29 102.0 0.2 4e-16 58.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAJ17716.1 - 1.5e-09 39.1 3.1 2.7e-09 38.2 3.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Hepar_II_III PF07940.13 OAJ17717.1 - 6e-06 26.1 0.1 1.2e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein MIP PF00230.20 OAJ17718.1 - 1.3e-47 162.4 4.6 1.9e-47 161.9 4.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.6 OAJ17718.1 - 0.12 12.6 2.3 0.29 11.4 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) GDWWSH PF15667.5 OAJ17718.1 - 0.5 9.7 2.7 0.95 8.8 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH Ribosomal_S19e PF01090.19 OAJ17719.1 - 0.15 11.7 0.2 2.1 8.1 0.2 2.6 3 0 0 3 3 3 0 Ribosomal protein S19e Porphobil_deam PF01379.20 OAJ17720.1 - 2.2e-68 229.8 0.0 8.7e-68 227.8 0.0 1.9 1 1 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAJ17720.1 - 4.7e-15 55.7 0.0 3.8e-09 36.8 0.1 2.5 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain ECH_1 PF00378.20 OAJ17721.1 - 2.2e-81 272.9 0.4 2.8e-81 272.5 0.4 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ17721.1 - 3e-34 119.0 0.9 9.4e-33 114.1 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAJ17721.1 - 0.00066 19.7 0.3 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 Avl9 PF09794.9 OAJ17722.1 - 3e-128 427.7 0.0 3.8e-128 427.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 OAJ17722.1 - 7.7e-08 32.3 0.0 0.0034 17.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 OAJ17722.1 - 3e-07 30.4 0.0 0.00043 20.2 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 OAJ17722.1 - 5.1e-05 23.8 0.1 0.00017 22.1 0.1 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF829 PF05705.14 OAJ17723.1 - 7e-27 94.9 0.1 5.8e-17 62.4 0.0 3.4 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) GST_C_2 PF13410.6 OAJ17740.1 - 1.9e-16 59.8 0.0 3.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ17740.1 - 4.1e-13 49.4 0.0 8.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ17740.1 - 2.3e-07 30.9 0.0 4.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ17740.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pmp3 PF01679.17 OAJ17741.1 - 4.3e-13 49.2 4.0 6.8e-13 48.6 4.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4485 PF14846.6 OAJ17741.1 - 0.27 11.3 2.3 0.19 11.8 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Nop10p PF04135.12 OAJ17741.1 - 0.29 11.2 2.7 6.5 6.9 0.2 2.5 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family SKN1 PF03935.15 OAJ17742.1 - 1.6e-176 587.6 1.1 1.9e-176 587.4 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MutS_V PF00488.21 OAJ17743.1 - 5.6e-65 218.9 0.4 1.4e-64 217.6 0.1 1.8 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 OAJ17743.1 - 2.3e-34 118.0 0.0 7.4e-34 116.4 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 OAJ17743.1 - 5.9e-33 114.7 2.5 1e-32 113.9 0.5 2.3 2 0 0 2 2 2 1 MutS domain III zf-C2H2_3 PF13878.6 OAJ17743.1 - 7.6e-14 51.3 2.8 1.5e-13 50.3 2.8 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_13 PF13880.6 OAJ17743.1 - 3.5e-13 49.3 0.0 8.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_II PF05188.17 OAJ17743.1 - 4.1e-11 43.3 0.1 1.2e-10 41.8 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ17743.1 - 2e-07 31.2 2.2 8.2e-07 29.3 1.2 2.3 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 OAJ17743.1 - 0.0088 15.8 1.1 0.028 14.2 0.3 2.2 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 OAJ17743.1 - 0.021 15.0 0.0 0.076 13.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3040 PF11239.8 OAJ17744.1 - 0.022 15.0 5.8 0.42 10.9 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) RhoGEF PF00621.20 OAJ17745.1 - 8.9e-24 84.7 0.3 8.9e-24 84.7 0.3 1.6 2 0 0 2 2 2 1 RhoGEF domain Plavaka PF18759.1 OAJ17745.1 - 0.18 11.0 0.0 0.64 9.2 0.0 1.7 2 0 0 2 2 2 0 Plavaka transposase COG5 PF10392.9 OAJ17746.1 - 4.3e-12 46.3 0.5 4.3e-12 46.3 0.5 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 SUIM_assoc PF16619.5 OAJ17746.1 - 0.012 15.6 0.1 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CENP-F_leu_zip PF10473.9 OAJ17746.1 - 0.15 12.1 2.2 2.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Transthyretin PF00576.21 OAJ17747.1 - 1.4e-34 119.1 0.0 5.8e-34 117.1 0.0 1.7 1 1 0 1 1 1 1 HIUase/Transthyretin family Fe-S_biosyn PF01521.20 OAJ17748.1 - 7.4e-15 55.1 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L7Ae PF01248.26 OAJ17749.1 - 1.3e-21 76.2 0.1 2.5e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ17749.1 - 0.0052 16.9 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 SAGA-Tad1 PF12767.7 OAJ17749.1 - 0.073 12.8 3.5 0.083 12.6 3.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4050 PF13259.6 OAJ17749.1 - 2 8.7 13.3 4.9 7.4 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) Ndc1_Nup PF09531.10 OAJ17749.1 - 2 7.0 4.7 2.4 6.8 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CRT10 PF08728.10 OAJ17749.1 - 4.3 5.4 8.1 5.4 5.0 8.1 1.0 1 0 0 1 1 1 0 CRT10 Macoilin PF09726.9 OAJ17749.1 - 4.7 5.6 10.4 5.2 5.5 10.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF3446 PF11928.8 OAJ17750.1 - 0.25 11.7 0.7 34 4.8 0.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain adh_short PF00106.25 OAJ17751.1 - 1.9e-29 102.5 0.1 2.6e-29 102.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ17751.1 - 1e-15 58.0 0.1 1.5e-15 57.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ17751.1 - 1.4e-05 25.1 0.9 4.7e-05 23.4 0.9 1.7 1 1 0 1 1 1 1 KR domain Sec23_trunk PF04811.15 OAJ17753.1 - 1.4e-71 241.0 0.0 2.1e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAJ17753.1 - 3.6e-23 81.3 0.7 7.6e-23 80.3 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAJ17753.1 - 4.3e-16 58.7 8.1 9.4e-16 57.6 8.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 OAJ17753.1 - 1.8e-15 57.5 0.0 5.1e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 OAJ17753.1 - 1.2e-09 37.9 0.0 2.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 OAJ17753.1 - 2.1e-07 30.9 0.8 5.1e-07 29.7 0.8 1.7 1 0 0 1 1 1 1 WW domain Vps36-NZF-N PF16988.5 OAJ17753.1 - 0.013 14.9 2.5 0.026 13.9 2.5 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ATG11 PF10377.9 OAJ17754.1 - 2.1e-29 102.2 0.0 6e-29 100.7 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 11 Fib_alpha PF08702.10 OAJ17754.1 - 2.8 8.1 22.0 0.22 11.7 1.4 5.3 5 1 0 6 6 6 0 Fibrinogen alpha/beta chain family Filament PF00038.21 OAJ17754.1 - 6.1 6.3 53.4 0.36 10.4 39.7 3.2 2 1 1 3 3 3 0 Intermediate filament protein DNA_repr_REX1B PF14966.6 OAJ17755.1 - 0.00023 21.7 3.2 0.53 11.0 0.1 4.0 3 1 0 3 3 3 1 DNA repair REX1-B ARA70 PF12489.8 OAJ17755.1 - 0.0095 16.1 0.2 0.015 15.5 0.2 1.3 1 0 0 1 1 1 1 Nuclear coactivator GLYCAM-1 PF05242.11 OAJ17755.1 - 0.098 12.8 5.4 0.12 12.5 1.9 2.1 1 1 1 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Fungal_trans PF04082.18 OAJ17756.1 - 1.3e-21 76.8 0.0 2.4e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17756.1 - 3.1e-09 36.8 2.8 6e-09 35.9 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.28 OAJ17757.1 - 7e-09 35.7 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sec63 PF02889.16 OAJ17758.1 - 9.8e-32 110.1 0.0 1.5e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAJ17758.1 - 2.6e-26 92.4 0.0 5.7e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ17758.1 - 6.2e-13 49.1 0.0 1.3e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ17758.1 - 1.4e-08 35.0 0.0 4.4e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 OAJ17758.1 - 0.00047 20.5 0.4 0.0016 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ17758.1 - 0.0043 16.8 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 OAJ17758.1 - 0.014 14.9 0.3 0.043 13.3 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 OAJ17758.1 - 0.048 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAJ17758.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 OAJ17758.1 - 0.13 12.5 0.1 0.85 9.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 OAJ17759.1 - 4.4e-21 75.1 12.5 4e-10 39.9 4.6 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ17759.1 - 9.4e-15 55.0 15.4 7.9e-09 36.0 0.8 2.7 3 0 0 3 3 3 2 HMG-box domain DUF3429 PF11911.8 OAJ17760.1 - 1.3e-40 139.0 14.4 1.9e-40 138.4 14.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Tubulin PF00091.25 OAJ17760.1 - 2.7 8.1 4.9 0.23 11.6 0.2 1.5 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain CCB2_CCB4 PF11152.8 OAJ17770.1 - 0.054 12.8 3.3 0.06 12.7 3.3 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 CytochromB561_N PF09786.9 OAJ17770.1 - 2.9 6.8 7.1 3 6.7 7.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal CRM1_repeat_3 PF18787.1 OAJ17770.1 - 3.2 7.9 9.1 18 5.5 0.2 3.1 1 1 2 3 3 3 0 CRM1 / Exportin repeat 3 HCO3_cotransp PF00955.21 OAJ17772.1 - 3.8e-55 187.7 15.0 5.9e-27 94.7 7.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family GCP_N_terminal PF17681.1 OAJ17773.1 - 4.8e-60 203.8 0.0 1.3e-27 97.3 0.0 3.6 3 0 0 3 3 3 3 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ17773.1 - 1.3e-42 146.4 5.6 2.4e-42 145.5 5.6 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal YL1 PF05764.13 OAJ17773.1 - 6.2e-06 26.5 11.2 6.2e-06 26.5 11.2 2.4 3 0 0 3 3 3 1 YL1 nuclear protein Nop53 PF07767.11 OAJ17773.1 - 0.0013 18.2 9.9 0.0013 18.2 9.9 2.5 3 0 0 3 3 3 1 Nop53 (60S ribosomal biogenesis) Apt1 PF10351.9 OAJ17773.1 - 0.0074 15.2 0.5 0.015 14.2 0.5 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain SDA1 PF05285.12 OAJ17773.1 - 0.008 15.6 13.0 0.021 14.3 13.0 1.6 1 0 0 1 1 1 1 SDA1 Rrn6 PF10214.9 OAJ17773.1 - 0.13 10.7 3.6 0.22 9.9 3.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 OAJ17773.1 - 0.2 9.9 20.9 0.38 9.0 20.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 OAJ17773.1 - 0.21 10.6 10.5 0.39 9.7 10.5 1.3 1 0 0 1 1 1 0 Pes-10 GCIP PF13324.6 OAJ17773.1 - 0.59 9.7 4.0 1.3 8.5 4.0 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 OAJ17773.1 - 1.3 7.2 17.7 2.5 6.2 17.7 1.4 1 0 0 1 1 1 0 Nop14-like family DUF4484 PF14831.6 OAJ17773.1 - 6.5 6.7 12.0 3.2 7.8 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Nucleoporin_FG2 PF15967.5 OAJ17774.1 - 8.4e-05 21.3 0.1 8.4e-05 21.3 0.1 1.4 1 1 1 2 2 2 1 Nucleoporin FG repeated region HrpB2 PF09487.10 OAJ17774.1 - 0.016 15.6 0.7 0.036 14.5 0.2 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) LemA PF04011.12 OAJ17774.1 - 0.051 13.4 0.6 0.14 12.0 0.0 2.0 2 1 0 2 2 2 0 LemA family VHS PF00790.19 OAJ17775.1 - 4.7e-40 136.7 0.0 1.2e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAJ17775.1 - 1.1e-18 67.2 1.9 1.3e-18 67.1 0.3 2.0 2 0 0 2 2 2 1 GAT domain Rubrerythrin PF02915.17 OAJ17775.1 - 0.074 13.4 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 Rubrerythrin FCD PF07729.12 OAJ17775.1 - 0.087 13.3 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 FCD domain IU_nuc_hydro PF01156.19 OAJ17776.1 - 1.7e-81 274.1 0.0 2.1e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SRF-TF PF00319.18 OAJ17776.1 - 0.17 11.4 0.1 0.34 10.4 0.1 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) WGG PF10273.9 OAJ17777.1 - 2.6e-20 72.8 0.0 5e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 OAJ17777.1 - 0.31 11.2 3.4 0.74 10.0 3.4 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CDC45 PF02724.14 OAJ17777.1 - 2.4 6.4 6.9 2.7 6.2 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein ELFV_dehydrog PF00208.21 OAJ17778.1 - 2.4e-73 246.8 1.2 3e-73 246.6 1.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 OAJ17778.1 - 9e-46 155.0 0.1 2.9e-45 153.3 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.25 OAJ17779.1 - 1.8e-49 168.5 0.0 1.8e-49 168.5 0.0 3.6 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17779.1 - 9.2e-22 77.6 0.0 9.2e-22 77.6 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase Exonuc_VII_L PF02601.15 OAJ17779.1 - 9 5.8 45.9 0.16 11.5 17.6 2.7 3 0 0 3 3 3 0 Exonuclease VII, large subunit Ofd1_CTDD PF10637.9 OAJ17780.1 - 7.4e-83 277.8 0.0 2e-78 263.3 0.0 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAJ17780.1 - 1.4e-32 112.2 0.0 3.2e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAJ17780.1 - 2.8e-15 57.0 0.0 9.1e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SKN1 PF03935.15 OAJ17781.1 - 1.6e-47 162.1 0.0 2e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ17782.1 - 2.8e-151 504.4 17.5 1.2e-85 287.9 17.1 2.9 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) GAPT PF11770.8 OAJ17783.1 - 0.25 11.2 0.2 0.41 10.5 0.2 1.2 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) D123 PF07065.14 OAJ17784.1 - 1.8e-76 257.3 0.0 4.7e-76 255.9 0.0 1.8 1 1 0 1 1 1 1 D123 CENP-B_dimeris PF09026.10 OAJ17784.1 - 0.35 11.3 24.1 3.7 8.0 13.1 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SDA1 PF05285.12 OAJ17784.1 - 0.54 9.6 9.4 0.059 12.8 3.0 2.1 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.13 OAJ17784.1 - 3.7 7.4 7.9 0.78 9.6 1.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region CDC45 PF02724.14 OAJ17784.1 - 7 4.8 5.7 13 3.9 5.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.13 OAJ17784.1 - 7.2 5.0 10.0 0.06 11.9 2.2 1.4 2 0 0 2 2 2 0 Utp14 protein Pkinase PF00069.25 OAJ17785.1 - 4.1e-62 209.9 0.0 5.3e-60 203.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17785.1 - 2.8e-22 79.3 0.0 2.1e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ17785.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ17785.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ17785.1 - 0.026 14.1 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 OAJ17785.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 OAJ17785.1 - 0.092 11.6 0.4 0.2 10.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.14 OAJ17785.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM199X PF15814.5 OAJ17785.1 - 0.32 10.0 5.0 0.51 9.3 5.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X Aconitase PF00330.20 OAJ17786.1 - 1.2e-149 499.3 0.0 2e-149 498.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ17786.1 - 7e-43 146.1 0.0 1.2e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain RRM_1 PF00076.22 OAJ17787.1 - 9.9e-23 79.8 0.0 1.3e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ17787.1 - 0.029 14.5 0.0 0.047 13.8 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif Glyoxal_oxid_N PF07250.11 OAJ17788.1 - 8.2e-20 71.0 1.2 1.5e-12 47.3 0.0 4.5 3 1 0 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 OAJ17788.1 - 9.3e-20 70.7 0.1 1.7e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKG6 PF08693.10 OAJ17788.1 - 0.24 10.8 1.3 0.49 9.8 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FXMRP1_C_core PF12235.8 OAJ17789.1 - 2.4 8.8 9.2 2.7 8.6 2.4 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal KRTAP PF11759.8 OAJ17790.1 - 1.8 9.1 24.4 1.7e+04 -3.6 24.4 2.6 1 1 0 1 1 1 0 Keratin-associated matrix SKN1 PF03935.15 OAJ17792.1 - 3.4e-47 161.0 3.4 4.2e-47 160.7 3.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF11 PF01345.18 OAJ17793.1 - 0.49 10.7 17.3 0.2 12.0 14.5 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF11 SCP2 PF02036.17 OAJ17794.1 - 2.2e-17 63.4 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ17794.1 - 0.026 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Mpp10 PF04006.12 OAJ17811.1 - 0.17 10.3 17.9 0.24 9.8 17.9 1.1 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 OAJ17811.1 - 2.3 6.2 28.5 6.6 4.7 28.9 1.6 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.12 OAJ17811.1 - 4.7 5.3 27.2 7.7 4.6 27.2 1.2 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 OAJ17811.1 - 7.1 5.5 19.4 11 4.9 19.4 1.2 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OAJ17811.1 - 7.2 4.8 18.5 13 4.0 18.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ17811.1 - 9.7 5.5 26.6 16 4.8 26.6 1.2 1 0 0 1 1 1 0 SDA1 TPR_2 PF07719.17 OAJ17812.1 - 0.00043 20.2 5.7 0.035 14.2 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ17812.1 - 0.00089 19.0 0.8 0.014 15.2 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17812.1 - 0.0032 17.6 6.2 0.009 16.2 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ17812.1 - 0.016 15.2 1.4 2.8 8.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ17812.1 - 0.045 13.8 0.9 6 7.0 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_16 PF13432.6 OAJ17812.1 - 0.91 10.2 11.1 6.4 7.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ17812.1 - 2.9 8.2 19.5 3.8 7.9 0.4 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat DHQ_synthase PF01761.20 OAJ17813.1 - 1.8e-46 158.5 0.0 2.2e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAJ17813.1 - 6.5e-12 45.7 0.0 9.2e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase ELF PF03317.13 OAJ17813.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 ELF protein AMP-binding PF00501.28 OAJ17815.1 - 1.1e-25 90.2 0.0 2.1e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ17815.1 - 1.2e-22 80.4 0.0 2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 OAJ17815.1 - 1.7e-08 34.7 0.2 4.2e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ17815.1 - 2e-07 30.7 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ17815.1 - 0.0034 17.3 0.0 0.02 14.8 0.0 2.2 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 OAJ17815.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.21 OAJ17816.1 - 2.2e-64 217.5 0.0 2.8e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RNB PF00773.19 OAJ17817.1 - 5.8e-98 328.2 0.0 8.9e-98 327.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 OAJ17817.1 - 1.2e-22 80.0 0.2 3.2e-22 78.6 0.2 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 OAJ17817.1 - 1.3e-21 76.4 0.0 2.8e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OAJ17817.1 - 0.0008 19.2 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain A_deaminase PF00962.22 OAJ17817.1 - 0.021 14.1 0.2 0.038 13.3 0.2 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Neur_chan_memb PF02932.16 OAJ17817.1 - 5.3 7.0 4.8 1 9.4 0.4 2.1 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region APH PF01636.23 OAJ17818.1 - 9.9e-18 64.9 0.2 2.3e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family SLT PF01464.20 OAJ17819.1 - 0.00024 20.7 0.0 0.0096 15.6 0.0 2.4 1 1 0 1 1 1 1 Transglycosylase SLT domain PGG PF13962.6 OAJ17820.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function IGR PF09597.10 OAJ17821.1 - 5.9e-09 35.9 2.4 1e-08 35.2 0.1 2.4 3 0 0 3 3 3 1 IGR protein motif FAT PF02259.23 OAJ17822.1 - 2.5e-65 221.0 2.0 7.1e-65 219.5 2.0 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ17822.1 - 8.1e-29 101.2 0.0 5.4e-28 98.5 0.0 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAJ17822.1 - 0.036 13.9 0.2 0.079 12.8 0.2 1.6 1 0 0 1 1 1 0 FATC domain Methyltransf_3 PF01596.17 OAJ17824.1 - 2.6e-47 160.7 0.0 4e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAJ17824.1 - 5.1e-12 46.8 0.0 1.2e-11 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ17824.1 - 0.005 16.5 0.0 0.0081 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 OAJ17824.1 - 0.014 16.1 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 OAJ17824.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_hydro_cc PF11790.8 OAJ17825.1 - 1.9e-53 181.5 2.1 2.2e-53 181.3 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Sporozoite_P67 PF05642.11 OAJ17840.1 - 0.0043 15.2 3.9 0.005 15.0 3.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen PBP1_TM PF14812.6 OAJ17840.1 - 0.02 15.2 5.4 0.022 15.1 3.4 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SDA1 PF05285.12 OAJ17840.1 - 0.025 14.0 4.2 0.026 14.0 4.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ17840.1 - 0.027 12.8 3.1 0.026 12.9 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 OAJ17840.1 - 0.052 13.3 4.8 0.069 12.9 4.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 OAJ17840.1 - 0.055 11.7 5.4 0.055 11.7 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family UPF0181 PF03701.14 OAJ17840.1 - 0.1 12.3 0.9 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) PI3K_1B_p101 PF10486.9 OAJ17840.1 - 0.25 9.1 1.4 0.25 9.1 1.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sigma70_ner PF04546.13 OAJ17840.1 - 0.37 10.7 9.6 0.52 10.2 9.6 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region eIF-3c_N PF05470.12 OAJ17840.1 - 0.38 9.0 1.2 0.34 9.2 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-B_dimeris PF09026.10 OAJ17840.1 - 0.72 10.3 14.3 1.1 9.7 14.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 OAJ17840.1 - 0.75 8.7 9.6 0.81 8.6 9.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein TFIIF_alpha PF05793.12 OAJ17840.1 - 0.91 8.0 8.5 1.1 7.8 8.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4746 PF15928.5 OAJ17840.1 - 0.99 8.8 5.9 1.2 8.6 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FAM176 PF14851.6 OAJ17840.1 - 1.1 8.9 7.6 1.8 8.2 7.6 1.4 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.11 OAJ17840.1 - 1.2 7.7 2.6 1.1 7.7 2.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 OAJ17840.1 - 1.8 8.3 10.4 2.7 7.7 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.9 OAJ17840.1 - 3 6.9 12.8 3.9 6.5 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop53 PF07767.11 OAJ17840.1 - 7.4 5.8 10.8 8.8 5.6 10.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CobT PF06213.12 OAJ17840.1 - 8.9 5.6 11.8 11 5.3 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 OAJ17840.1 - 9.1 4.2 15.9 12 3.9 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apolipoprotein PF01442.18 OAJ17841.1 - 0.0017 18.3 10.9 0.0026 17.7 10.4 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain REF PF05755.12 OAJ17841.1 - 0.005 16.7 8.4 0.0071 16.2 8.4 1.2 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) Meiotic_rec114 PF03525.14 OAJ17841.1 - 1 8.3 6.5 1.3 7.9 6.5 1.1 1 0 0 1 1 1 0 Meiotic recombination protein rec114 SOAR PF16533.5 OAJ17841.1 - 1.3 9.1 6.0 0.54 10.3 1.7 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region DUF883 PF05957.13 OAJ17841.1 - 3.3 8.4 15.1 1.1 9.9 6.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.15 OAJ17842.1 - 0.21 11.4 0.7 0.45 10.3 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator RabGAP-TBC PF00566.18 OAJ17843.1 - 5.6e-49 166.7 0.0 7.7e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 OAJ17843.1 - 0.0065 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ17843.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain ORC6 PF05460.13 OAJ17843.1 - 4.2 6.5 18.8 0.91 8.7 3.3 2.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_1 PF00561.20 OAJ17846.1 - 5e-14 52.6 0.0 6.8e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17846.1 - 0.0063 17.1 0.1 0.019 15.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF5572 PF17733.1 OAJ17848.1 - 0.0096 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Nuclease_act PF08133.11 OAJ17849.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Anticodon nuclease activator family SET PF00856.28 OAJ17850.1 - 3.9e-19 69.7 0.3 3.9e-19 69.7 0.3 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.11 OAJ17850.1 - 8e-18 64.4 7.9 3.3e-17 62.4 7.9 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 OAJ17850.1 - 2.2e-12 46.8 4.4 2.2e-12 46.8 4.4 2.2 2 0 0 2 2 2 1 AWS domain Macoilin PF09726.9 OAJ17850.1 - 4.9 5.6 16.8 9 4.7 16.8 1.3 1 0 0 1 1 1 0 Macoilin family Corona_nucleoca PF00937.18 OAJ17850.1 - 5.9 5.8 22.3 3.2 6.7 2.8 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein PNISR PF15996.5 OAJ17850.1 - 9.6 6.4 24.9 8 6.7 0.6 2.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Autophagy_act_C PF03987.15 OAJ17851.1 - 5.6e-17 62.1 0.1 1.6e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ctr PF04145.15 OAJ17852.1 - 0.08 13.6 1.6 6 7.5 0.0 3.4 3 1 0 3 3 3 0 Ctr copper transporter family HemY_N PF07219.13 OAJ17852.1 - 0.15 12.3 0.2 0.15 12.3 0.2 4.4 4 1 1 5 5 5 0 HemY protein N-terminus DNA_pol_phi PF04931.13 OAJ17853.1 - 1.4e-141 473.1 27.9 4.9e-140 468.1 27.9 2.2 1 1 0 1 1 1 1 DNA polymerase phi Spt20 PF12090.8 OAJ17853.1 - 0.0049 16.5 0.0 0.0049 16.5 0.0 2.5 2 0 0 2 2 2 1 Spt20 family Peptidase_C50 PF03568.17 OAJ17853.1 - 0.023 13.8 0.0 0.073 12.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C50 RRN3 PF05327.11 OAJ17853.1 - 0.43 9.1 21.8 0.068 11.7 17.3 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Na_trans_assoc PF06512.13 OAJ17853.1 - 3.7 7.8 20.2 0.022 15.0 4.9 3.4 1 1 1 2 2 2 0 Sodium ion transport-associated ABC1 PF03109.16 OAJ17854.1 - 2.2e-24 85.9 0.0 3.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.9 OAJ17854.1 - 0.063 13.0 4.4 0.2 11.4 4.4 2.0 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Abhydrolase_4 PF08386.10 OAJ17856.1 - 6.3e-15 55.2 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein RRM_1 PF00076.22 OAJ17857.1 - 7.1e-13 48.2 0.0 1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ17857.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif OPA3 PF07047.12 OAJ17858.1 - 2.1e-42 143.8 4.0 2.1e-42 143.8 4.0 1.9 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Histone_HNS PF00816.21 OAJ17858.1 - 0.57 11.0 10.0 0.8 10.6 2.2 2.8 3 0 0 3 3 3 0 H-NS histone family DDRGK PF09756.9 OAJ17858.1 - 5.9 6.4 11.0 11 5.6 11.0 1.3 1 0 0 1 1 1 0 DDRGK domain Pyr_redox_2 PF07992.14 OAJ17859.1 - 2.8e-66 223.7 8.1 2.8e-66 223.7 8.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ17859.1 - 2.4e-41 140.5 0.1 5.6e-41 139.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ17859.1 - 9.8e-21 74.1 8.5 1.3e-17 64.1 1.9 3.5 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ17859.1 - 1.4e-11 44.2 6.1 1.8e-08 34.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ17859.1 - 2.1e-11 43.9 0.3 2.1e-11 43.9 0.3 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 OAJ17859.1 - 1.1e-09 37.8 9.9 3.6e-09 36.2 2.7 2.8 2 2 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAJ17859.1 - 1.1e-08 35.1 3.8 5.7e-05 23.3 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ17859.1 - 3.4e-07 29.7 2.2 3.4e-07 29.7 2.2 3.6 3 1 2 5 5 5 1 FAD binding domain K_oxygenase PF13434.6 OAJ17859.1 - 1e-06 28.2 0.8 0.061 12.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 OAJ17859.1 - 1.7e-06 27.0 13.1 0.00013 20.8 1.1 4.0 4 0 0 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ17859.1 - 7.7e-06 25.3 4.5 0.012 14.9 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAJ17859.1 - 0.00018 20.9 0.1 0.00018 20.9 0.1 2.6 2 1 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 OAJ17859.1 - 0.00038 19.8 11.8 0.012 14.9 1.2 3.5 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 OAJ17859.1 - 0.011 15.4 17.2 0.11 12.1 0.5 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.19 OAJ17859.1 - 0.025 13.9 0.2 0.08 12.3 0.2 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 OAJ17859.1 - 0.094 11.7 4.9 0.15 11.1 0.1 2.9 3 1 0 3 3 3 0 Lycopene cyclase protein DUF1176 PF06674.11 OAJ17862.1 - 0.1 12.0 3.6 0.17 11.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Abhydrolase_3 PF07859.13 OAJ17877.1 - 1.8e-31 109.7 0.3 5.1e-22 78.8 0.0 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_31 PF13847.6 OAJ17879.1 - 2.1e-09 37.4 0.0 3.7e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ17879.1 - 1.5e-06 28.8 0.0 4.3e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 OAJ17879.1 - 2.4e-05 23.8 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MTS PF05175.14 OAJ17879.1 - 6.2e-05 22.6 1.2 0.01 15.4 0.0 3.2 2 1 0 3 3 3 1 Methyltransferase small domain FtsJ PF01728.19 OAJ17879.1 - 0.00042 20.5 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 OAJ17879.1 - 0.0096 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAJ17879.1 - 0.011 15.6 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ17879.1 - 0.011 16.3 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ17879.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 OAJ17879.1 - 0.055 13.1 0.2 1.7 8.3 0.1 3.0 1 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.12 OAJ17879.1 - 0.097 12.0 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 RNA methyltransferase Methyltransf_12 PF08242.12 OAJ17879.1 - 0.12 13.2 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3818 PF12825.7 OAJ17880.1 - 4.9e-127 423.6 0.0 7.5e-127 423.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ17880.1 - 5.6e-40 136.3 1.3 1e-39 135.5 1.3 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAJ17880.1 - 2.2e-08 34.0 0.0 1.1e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 PX domain Taeniidae_ag PF05596.11 OAJ17880.1 - 0.71 9.9 3.3 7.6 6.6 0.2 3.3 3 0 0 3 3 3 0 Taeniidae antigen Mannosyl_trans2 PF04188.13 OAJ17882.1 - 2.2e-55 188.7 13.1 2.7e-55 188.5 13.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) GSAP-16 PF14959.6 OAJ17882.1 - 0.085 12.7 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Tau95 PF09734.9 OAJ17883.1 - 5.2e-27 95.4 0.1 9.8e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OAJ17883.1 - 1.8e-15 57.3 0.0 5.9e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 Tau95 Triple barrel domain Suc_Fer-like PF06999.12 OAJ17884.1 - 1e-44 152.8 0.0 1.8e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Rhomboid PF01694.22 OAJ17885.1 - 1.4e-27 96.6 13.4 1.4e-27 96.6 13.4 1.9 3 0 0 3 3 3 1 Rhomboid family zf-C2H2_2 PF12756.7 OAJ17886.1 - 3.7e-38 129.9 3.4 3.7e-29 101.0 0.0 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAJ17886.1 - 1.3e-08 34.9 12.5 1.6e-06 28.2 4.0 3.5 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ17886.1 - 1.1e-07 32.0 6.6 2.9e-07 30.6 2.7 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAJ17886.1 - 0.00013 22.5 11.6 0.17 12.8 0.2 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ17886.1 - 0.0024 18.2 17.7 0.3 11.6 0.7 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 OAJ17886.1 - 0.042 14.5 0.7 0.45 11.2 0.5 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats AKAP95 PF04988.12 OAJ17886.1 - 0.063 13.5 0.7 0.14 12.3 0.7 1.6 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.6 OAJ17886.1 - 0.082 12.9 11.6 0.1 12.6 1.1 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 OAJ17886.1 - 0.15 12.6 1.7 3 8.4 0.1 3.2 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger SR-25 PF10500.9 OAJ17886.1 - 0.36 10.4 9.5 0.78 9.3 9.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-BED PF02892.15 OAJ17886.1 - 0.4 10.7 4.3 1.1 9.3 0.5 2.7 2 0 0 2 2 2 0 BED zinc finger zf-DBF PF07535.12 OAJ17886.1 - 0.42 10.8 2.2 0.94 9.6 0.2 2.4 2 0 0 2 2 2 0 DBF zinc finger HNH_5 PF14279.6 OAJ17886.1 - 0.58 10.0 3.2 4.4 7.2 0.1 3.5 4 0 0 4 4 4 0 HNH endonuclease zf_C2H2_ZHX PF18387.1 OAJ17886.1 - 2 8.1 10.3 3.1 7.5 0.1 3.9 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Myb_DNA-binding PF00249.31 OAJ17887.1 - 3.6e-11 43.1 0.0 9.7e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OAJ17887.1 - 2.6e-09 37.3 0.1 6.7e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 OAJ17887.1 - 3.6e-08 33.1 5.5 5.9e-08 32.4 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OAJ17887.1 - 1.9e-06 28.0 0.0 5.8e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain DSS1_SEM1 PF05160.13 OAJ17888.1 - 7.5e-18 64.3 14.9 5.4e-17 61.6 14.9 2.1 1 1 0 1 1 1 1 DSS1/SEM1 family KH_1 PF00013.29 OAJ17889.1 - 1.6e-10 40.7 0.1 2e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 OAJ17889.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 NusA-like KH domain PP2C PF00481.21 OAJ17890.1 - 4e-47 161.0 0.1 7.1e-47 160.2 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAJ17890.1 - 4e-41 138.6 55.9 8.7e-09 35.0 2.7 9.7 4 2 7 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 OAJ17890.1 - 1.4e-35 120.7 68.3 3.4e-06 27.3 0.3 12.5 4 2 8 15 15 15 14 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAJ17890.1 - 1e-24 87.1 0.0 1.9e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 OAJ17890.1 - 0.00037 20.6 37.6 3.2 8.6 0.0 13.8 13 2 0 13 13 13 2 Leucine Rich Repeat LRR_9 PF14580.6 OAJ17890.1 - 0.0066 16.0 18.2 0.013 15.1 1.7 4.3 2 1 3 5 5 5 2 Leucine-rich repeat RA PF00788.23 OAJ17890.1 - 0.024 15.2 0.0 0.049 14.3 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Pkinase PF00069.25 OAJ17891.1 - 8.7e-51 172.8 0.0 8.7e-51 172.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17891.1 - 5.9e-20 71.6 0.0 1.5e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ17891.1 - 0.0043 17.0 0.1 0.0043 17.0 0.1 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ17891.1 - 0.056 13.0 0.1 0.056 13.0 0.1 2.5 3 0 0 3 3 3 0 RIO1 family eIF3_subunit PF08597.10 OAJ17891.1 - 1.2 9.0 27.2 1.4 8.8 3.6 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF737 PF05300.11 OAJ17891.1 - 1.4 9.2 30.5 1.4 9.2 9.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Neur_chan_memb PF02932.16 OAJ17891.1 - 5.3 7.0 25.1 3.6 7.6 7.8 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.13 OAJ17891.1 - 8.2 5.4 34.9 0.089 11.8 6.8 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor tRNA-synt_2 PF00152.20 OAJ17893.1 - 1.3e-70 237.9 0.1 1.8e-70 237.5 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAJ17893.1 - 8.1e-18 64.5 0.1 1.4e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA-synt_2d PF01409.20 OAJ17893.1 - 0.0002 20.9 1.2 0.5 9.8 0.4 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 OAJ17893.1 - 0.00071 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ERM PF00769.19 OAJ17893.1 - 0.0088 15.9 2.0 0.3 10.9 0.1 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family DUF3774 PF12609.8 OAJ17893.1 - 0.074 14.1 0.8 0.36 11.9 0.2 2.5 2 0 0 2 2 2 0 Wound-induced protein Cwf_Cwc_15 PF04889.12 OAJ17893.1 - 0.075 12.8 0.1 0.075 12.8 0.1 3.4 5 0 0 5 5 5 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_3 PF07859.13 OAJ17894.1 - 1.3e-41 142.8 0.2 4.2e-41 141.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 OAJ17894.1 - 1e-06 27.9 0.0 3.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 OAJ17894.1 - 0.0044 15.9 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Lactamase_B_2 PF12706.7 OAJ17894.1 - 0.049 13.1 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Peptidase_S9 PF00326.21 OAJ17894.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.12 OAJ17894.1 - 0.16 10.6 0.0 6.2 5.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 OAJ17895.1 - 9.2e-87 292.0 0.0 1.1e-86 291.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ17895.1 - 2.8e-05 24.1 0.0 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Mg_trans_NIPA PF05653.14 OAJ17896.1 - 6.3e-94 314.4 25.8 8.6e-94 314.0 25.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ17896.1 - 0.0077 16.4 13.9 0.0077 16.4 13.9 3.2 2 2 0 2 2 2 1 EamA-like transporter family RVT_1 PF00078.27 OAJ17912.1 - 3.8e-23 82.2 0.0 7.7e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ17912.1 - 2.6e-21 75.5 0.0 2e-12 47.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ17912.1 - 8e-17 61.4 0.0 1.5e-11 44.5 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ17912.1 - 1e-13 51.2 0.0 2.2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ17912.1 - 4.8e-12 46.1 0.0 1.6e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ17912.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RecQ_Zn_bind PF16124.5 OAJ17916.1 - 1.3e-07 32.2 0.6 2.9e-07 31.1 0.6 1.6 1 0 0 1 1 1 1 RecQ zinc-binding CDC45 PF02724.14 OAJ17916.1 - 0.053 11.8 2.9 0.058 11.7 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Retrotrans_gag PF03732.17 OAJ17917.1 - 0.034 14.4 0.1 0.36 11.1 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein Dynamitin PF04912.14 OAJ17917.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynamitin DDE_Tnp_4 PF13359.6 OAJ17918.1 - 4.7e-20 71.8 0.0 6.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ17918.1 - 1.6e-08 34.4 0.0 7.9e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1_2 PF13586.6 OAJ17918.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 OAJ17918.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Transposase DDE domain Periviscerokin PF08259.11 OAJ17918.1 - 0.21 11.9 0.7 5.3 7.7 0.4 2.5 2 0 0 2 2 2 0 Periviscerokinin family FadA PF09403.10 OAJ17919.1 - 0.09 13.3 0.1 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Adhesion protein FadA DEAD PF00270.29 OAJ17920.1 - 1.3e-13 51.1 0.2 1.5e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Mito_fiss_reg PF05308.11 OAJ17920.1 - 0.019 15.1 3.2 0.027 14.6 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ResIII PF04851.15 OAJ17920.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 OAJ17920.1 - 0.14 10.9 0.0 0.28 9.9 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Chitin_bind_1 PF00187.19 OAJ17921.1 - 5.4 7.6 19.4 0.51 10.9 7.4 2.8 3 1 0 3 3 3 0 Chitin recognition protein HTH_23 PF13384.6 OAJ17922.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_3 PF12776.7 OAJ17923.1 - 9.4e-10 39.4 0.7 1.9e-09 38.4 0.7 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ17923.1 - 2.1e-05 24.8 0.7 5.9e-05 23.4 0.2 2.0 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain LIN37 PF15306.6 OAJ17923.1 - 0.65 10.2 4.7 0.87 9.8 1.2 2.5 2 1 0 2 2 2 0 LIN37 NOA36 PF06524.12 OAJ17923.1 - 3.8 6.7 9.4 6.5 6.0 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ17923.1 - 8.1 4.6 12.7 15 3.7 12.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Pur_ac_phosph_N PF16656.5 OAJ17924.1 - 4.9e-13 49.5 0.5 6.1e-13 49.2 0.5 1.2 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 OAJ17924.1 - 0.001 19.6 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 OAJ17924.1 - 0.025 14.9 1.5 0.053 13.9 1.5 1.6 1 1 0 1 1 1 0 Fibronectin type III domain Plant_tran PF04827.14 OAJ17926.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein Abhydrolase_4 PF08386.10 OAJ17928.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Dimer_Tnp_hAT PF05699.14 OAJ17930.1 - 2.2e-10 40.2 0.0 5.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1518 PF07469.12 OAJ17931.1 - 0.075 13.4 5.6 2.8 8.4 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Mitofilin PF09731.9 OAJ17933.1 - 0.37 9.6 8.7 0.41 9.4 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Roughex PF06020.11 OAJ17933.1 - 0.57 9.2 6.7 0.67 9.0 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF3292 PF11696.8 OAJ17933.1 - 3.7 5.8 9.1 4.6 5.5 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TFIIA PF03153.13 OAJ17933.1 - 6.5 6.6 17.5 7.3 6.5 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 4HBT PF03061.22 OAJ17952.1 - 2.2e-09 37.5 0.1 3.9e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAJ17952.1 - 0.0021 18.2 0.0 0.0071 16.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4442) GATA PF00320.27 OAJ17954.1 - 9.3e-14 50.7 2.9 1.8e-13 49.8 2.9 1.5 1 0 0 1 1 1 1 GATA zinc finger Spt20 PF12090.8 OAJ17954.1 - 0.35 10.5 5.4 0.67 9.5 5.4 1.4 1 0 0 1 1 1 0 Spt20 family RhoGAP PF00620.27 OAJ17955.1 - 2.1e-35 121.8 0.0 3.1e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain PalH PF08733.10 OAJ17956.1 - 0.051 12.6 9.1 0.11 11.5 9.1 1.5 1 1 0 1 1 1 0 PalH/RIM21 Zip PF02535.22 OAJ17957.1 - 0.028 13.7 0.5 0.028 13.7 0.5 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Ald_Xan_dh_C2 PF02738.18 OAJ17959.1 - 1.6e-185 617.7 0.0 2.5e-185 617.1 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OAJ17959.1 - 6.8e-30 103.7 0.0 1.6e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 OAJ17959.1 - 1.8e-24 86.4 0.3 1.8e-23 83.1 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OAJ17959.1 - 2.3e-24 85.2 0.1 5e-24 84.1 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OAJ17959.1 - 2.1e-21 76.0 1.4 5.4e-21 74.7 0.0 2.6 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OAJ17959.1 - 3e-06 27.1 0.1 3.6e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPR_1 PF00515.28 OAJ17960.1 - 0.0018 18.0 7.7 34 4.5 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17960.1 - 0.073 13.2 15.3 12 6.3 0.1 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ17960.1 - 0.35 11.4 4.8 29 5.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17960.1 - 1.3 9.4 6.5 30 5.2 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Vps8 PF12816.7 OAJ17961.1 - 1.9e-60 203.8 0.0 3.9e-60 202.8 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 ANAPC4_WD40 PF12894.7 OAJ17961.1 - 0.038 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OAJ17961.1 - 0.057 13.3 0.2 13 5.7 0.1 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS Kin17_mid PF10357.9 OAJ17962.1 - 1.2e-46 157.7 0.1 2.2e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein TPR_1 PF00515.28 OAJ17963.1 - 0.00024 20.8 2.9 2 8.4 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17963.1 - 0.00086 19.2 13.4 1.3 9.3 0.1 6.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ17963.1 - 0.0011 19.2 16.3 0.0017 18.6 0.3 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17963.1 - 0.0018 18.4 0.3 0.6 10.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ17963.1 - 0.0019 18.7 0.3 5.5 7.9 0.1 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ17963.1 - 0.021 14.9 2.3 0.32 11.1 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 OAJ17963.1 - 0.025 14.6 0.1 19 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ17963.1 - 0.17 12.4 13.0 0.72 10.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OAJ17963.1 - 0.2 11.7 2.9 0.39 10.8 0.1 2.9 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 OAJ17963.1 - 0.28 12.1 16.5 23 6.1 0.0 6.9 5 2 3 8 8 8 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 OAJ17964.1 - 1e-19 71.0 0.0 1.8e-12 47.4 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Fungal_trans PF04082.18 OAJ17966.1 - 4.5e-13 48.8 0.1 8.2e-12 44.7 0.1 2.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ17966.1 - 1.9e-05 24.7 9.4 3.5e-05 23.8 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD-helicase PF00580.21 OAJ17967.1 - 3.9e-65 220.4 0.2 7.3e-65 219.5 0.2 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OAJ17967.1 - 2.4e-58 198.2 0.0 3.6e-28 98.9 0.0 3.0 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAJ17967.1 - 1.2e-30 106.7 0.0 2.8e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ17967.1 - 3.9e-11 42.6 0.0 1.2e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OAJ17967.1 - 4.1e-06 26.7 0.1 0.14 11.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OAJ17967.1 - 0.011 15.6 0.6 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Helicase AAA_12 PF13087.6 OAJ17967.1 - 0.045 13.4 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain WLM PF08325.10 OAJ17968.1 - 5.6e-49 166.8 1.0 4.6e-48 163.8 0.0 2.5 3 0 0 3 3 3 1 WLM domain zf-RanBP PF00641.18 OAJ17968.1 - 3e-06 26.4 2.2 4.7e-06 25.8 2.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 OAJ17968.1 - 0.096 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 LAG1-DNAbind PF09271.11 OAJ17969.1 - 1.5e-27 97.1 5.2 1.8e-27 96.8 0.0 2.8 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 OAJ17969.1 - 1e-06 29.1 0.0 2.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain Glyco_transf_90 PF05686.12 OAJ17970.1 - 3.4e-21 75.6 2.3 1e-14 54.3 0.6 3.0 3 0 0 3 3 3 3 Glycosyl transferase family 90 EMP24_GP25L PF01105.24 OAJ17982.1 - 5e-39 134.1 0.3 6.8e-39 133.7 0.3 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD JmjC PF02373.22 OAJ17983.1 - 7.9e-39 132.6 0.1 1.5e-38 131.7 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ17983.1 - 3.7e-16 58.8 0.3 8.6e-16 57.6 0.3 1.7 1 0 0 1 1 1 1 jmjN domain WD40 PF00400.32 OAJ17984.1 - 1.8e-44 148.8 21.8 6.3e-08 33.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ17984.1 - 4.1e-11 43.0 0.1 0.023 15.0 0.0 4.8 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ17984.1 - 9.2e-07 27.9 4.3 0.096 11.3 0.2 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAJ17984.1 - 0.024 13.6 0.1 29 3.5 0.0 3.6 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ17984.1 - 0.032 14.2 3.3 22 5.1 0.0 4.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 OAJ17984.1 - 0.085 11.4 0.1 2.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 OAJ17984.1 - 0.19 11.0 0.0 23 4.2 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain GMC_oxred_N PF00732.19 OAJ17985.1 - 6.4e-39 134.1 0.0 9.4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ17985.1 - 4.8e-22 79.0 0.7 8.9e-20 71.7 1.0 3.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ17985.1 - 1.1e-08 34.7 0.4 2.6e-06 26.8 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ17985.1 - 9e-06 25.5 0.4 0.002 17.8 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ17985.1 - 1.3e-05 24.6 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ17985.1 - 4.7e-05 23.5 0.2 0.00012 22.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ17985.1 - 0.00059 19.1 0.1 0.0014 17.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ17985.1 - 0.0078 15.0 0.5 0.015 14.1 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 OAJ17985.1 - 0.0089 15.4 1.8 0.013 14.9 1.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ17985.1 - 0.029 13.6 0.2 0.054 12.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAJ17985.1 - 0.04 13.0 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAJ17985.1 - 0.063 12.3 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAJ17985.1 - 0.069 12.8 0.7 0.13 12.0 0.7 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAJ17985.1 - 0.085 12.1 0.1 0.19 10.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAJ17985.1 - 0.29 10.7 0.5 0.51 9.9 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF155 PF02582.14 OAJ17987.1 - 3.9e-33 115.0 1.3 7.3e-32 110.9 1.3 2.7 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3309 PF11752.8 OAJ17987.1 - 0.21 11.7 1.0 20 5.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) Macoilin PF09726.9 OAJ17987.1 - 0.47 9.0 7.0 0.022 13.3 0.8 1.9 2 0 0 2 2 2 0 Macoilin family GREB1 PF15782.5 OAJ17987.1 - 1.4 5.9 8.5 2.1 5.4 4.9 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer PPR_2 PF13041.6 OAJ17988.1 - 3.5e-34 116.8 0.4 6.9e-08 32.6 0.0 9.5 9 1 1 10 10 10 4 PPR repeat family PPR PF01535.20 OAJ17988.1 - 4.6e-21 73.5 0.8 0.0039 17.3 0.1 10.3 11 2 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 OAJ17988.1 - 1.3e-20 73.2 0.0 1e-06 28.7 0.0 8.5 8 1 3 11 11 11 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAJ17988.1 - 7.4e-11 41.6 4.9 0.0019 17.9 0.0 8.0 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 OAJ17988.1 - 8.1e-10 38.4 0.3 1.3e-06 27.9 0.0 3.4 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 OAJ17988.1 - 0.00036 20.3 0.1 2.9 8.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ17988.1 - 0.056 14.3 22.7 3 8.9 0.2 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17988.1 - 0.078 13.1 0.1 35 4.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 OAJ17989.1 - 6.9e-35 119.0 0.0 7.2e-12 45.3 0.0 8.0 8 1 2 10 10 10 6 PPR repeat family PPR_3 PF13812.6 OAJ17989.1 - 2.6e-24 85.1 0.0 2.1e-12 46.9 0.0 5.8 4 2 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 OAJ17989.1 - 6.7e-24 82.4 6.4 4.6e-05 23.4 0.0 10.8 12 2 0 12 12 12 3 PPR repeat PPR_1 PF12854.7 OAJ17989.1 - 1.2e-17 63.3 3.7 3.9e-07 29.7 0.0 6.7 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 OAJ17989.1 - 1.8e-16 60.1 0.0 2.4e-13 50.0 0.0 3.8 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP Rad60-SLD PF11976.8 OAJ17990.1 - 1.1e-22 79.6 0.2 1.3e-22 79.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ17990.1 - 2.1e-12 46.6 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_1b PF00579.25 OAJ17991.1 - 2.7e-59 200.9 0.0 8.5e-59 199.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) SpoIIE PF07228.12 OAJ17993.1 - 1.7e-07 31.3 0.0 0.052 13.5 0.0 3.4 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 OAJ17993.1 - 6e-05 22.8 0.1 0.00064 19.4 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 OAJ17993.1 - 0.00072 19.3 8.2 0.012 15.2 0.2 3.6 2 1 1 3 3 3 2 Protein phosphatase 2C SUIM_assoc PF16619.5 OAJ17993.1 - 5.9 7.0 11.3 23 5.1 4.0 3.9 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_2 PF00891.18 OAJ17994.1 - 4.9e-25 88.1 0.0 3.1e-20 72.4 0.0 2.7 3 0 0 3 3 3 2 O-methyltransferase domain Rrf2 PF02082.20 OAJ17994.1 - 0.11 12.9 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator TPR_1 PF00515.28 OAJ17995.1 - 1.3e-28 97.6 24.7 1.9e-06 27.4 1.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17995.1 - 2.4e-27 92.8 30.6 2.1e-05 24.3 0.0 11.2 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ17995.1 - 8.3e-21 74.4 24.6 1.8e-07 31.7 0.0 6.7 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ17995.1 - 2.8e-20 70.7 21.6 1.5e-05 24.8 0.0 9.3 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ17995.1 - 7.4e-20 69.8 13.3 5.3e-05 23.3 0.1 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ17995.1 - 6.2e-17 61.7 24.3 7.6e-05 22.9 0.0 8.5 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ17995.1 - 1.4e-13 50.3 28.3 0.00034 20.2 0.1 8.1 5 1 4 9 9 9 6 TPR repeat TPR_14 PF13428.6 OAJ17995.1 - 1.5e-11 44.1 22.8 0.0069 17.1 0.0 9.7 4 3 7 11 11 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ17995.1 - 3.8e-10 39.9 13.6 0.00061 20.0 0.4 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ17995.1 - 2.4e-09 37.2 11.8 0.0031 17.6 0.1 6.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ17995.1 - 1.1e-08 35.4 34.0 0.00026 21.4 1.2 6.9 6 2 3 9 9 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ17995.1 - 3.2e-07 29.9 19.2 0.36 11.0 0.1 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ17995.1 - 0.0052 16.6 19.7 7.2 6.6 0.0 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ17995.1 - 0.028 14.7 11.5 6.6 7.1 0.5 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OAJ17995.1 - 0.032 14.3 0.2 0.57 10.3 0.1 2.9 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 OAJ17995.1 - 0.062 14.0 0.0 0.062 14.0 0.0 7.6 10 0 0 10 10 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ17995.1 - 0.12 12.5 11.6 0.15 12.2 0.1 4.9 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 OAJ17995.1 - 0.95 10.3 7.3 17 6.4 0.1 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAJ17995.1 - 1.8 8.7 6.4 15 5.7 0.0 4.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat eIF3_N PF09440.10 OAJ17996.1 - 3.5e-41 140.8 3.5 4.6e-41 140.4 1.5 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAJ17996.1 - 6.6e-10 39.4 0.1 1.3e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OAJ17996.1 - 0.033 14.4 0.2 1.4 9.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ17996.1 - 5.2 7.4 6.4 4.5 7.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RhoGEF PF00621.20 OAJ17997.1 - 1.4e-29 103.7 0.2 2.1e-29 103.0 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.22 OAJ17998.1 - 2.5e-08 33.6 0.0 3.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_1 PF00534.20 OAJ17999.1 - 2.7e-18 66.1 0.0 2.3e-13 50.0 0.0 3.2 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ17999.1 - 2.6e-09 37.3 0.2 1.4e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAJ17999.1 - 4.1e-05 24.0 3.8 6.9e-05 23.3 0.0 2.9 3 1 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ17999.1 - 0.003 18.0 0.1 0.003 18.0 0.1 3.6 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 OAJ17999.1 - 0.0097 16.0 0.0 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus ADH_N_2 PF16884.5 OAJ18000.1 - 9e-35 118.8 0.0 1.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAJ18000.1 - 1.8e-18 66.7 0.1 3e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ18000.1 - 2.4e-08 35.1 0.0 8.5e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAJ18000.1 - 0.0084 15.6 0.2 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAJ18000.1 - 0.031 13.7 0.0 0.37 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PhnA PF03831.14 OAJ18000.1 - 0.067 13.1 0.3 19 5.2 0.0 3.3 4 0 0 4 4 4 0 PhnA domain Methyltransf_2 PF00891.18 OAJ18001.1 - 2.4e-23 82.6 0.0 1.9e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Rrf2 PF02082.20 OAJ18001.1 - 0.0033 17.7 0.0 0.096 13.0 0.0 2.5 2 0 0 2 2 2 1 Transcriptional regulator DSBA PF01323.20 OAJ18001.1 - 0.0038 17.0 0.1 0.24 11.1 0.1 2.5 2 1 0 2 2 2 1 DSBA-like thioredoxin domain HTH_IclR PF09339.10 OAJ18001.1 - 0.05 13.4 0.1 0.52 10.2 0.0 2.6 3 0 0 3 3 3 0 IclR helix-turn-helix domain RPA_C PF08784.11 OAJ18001.1 - 0.07 13.8 0.0 0.17 12.6 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal RPAP1_N PF08621.10 OAJ18002.1 - 0.12 12.1 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal Hexapep PF00132.24 OAJ18003.1 - 2.2e-10 39.9 6.2 1.3e-08 34.2 4.9 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ18003.1 - 2.3e-10 40.0 5.8 5.2e-10 38.9 4.4 2.1 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAJ18003.1 - 1.1e-09 38.4 0.0 3e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Maltose acetyltransferase Bin3 PF06859.12 OAJ18005.1 - 1.3e-16 61.1 0.0 1.7e-13 51.1 0.0 2.7 2 1 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 OAJ18005.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ18005.1 - 0.00035 21.2 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ18005.1 - 0.026 15.2 0.0 0.065 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DAGK_cat PF00781.24 OAJ18005.1 - 0.038 13.6 0.1 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PCMT PF01135.19 OAJ18005.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 OAJ18005.1 - 0.087 12.8 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ18005.1 - 0.14 13.0 0.0 0.65 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 OAJ18005.1 - 0.16 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Cyclin_N PF00134.23 OAJ18018.1 - 2.7e-42 143.5 0.2 1.5e-41 141.1 0.2 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ18018.1 - 7.6e-29 100.2 0.0 2.2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gemini_AL3 PF01407.17 OAJ18018.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Geminivirus AL3 protein Peptidase_S64 PF08192.11 OAJ18018.1 - 9.7 4.5 10.1 12 4.2 10.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 NuA4 PF09340.10 OAJ18019.1 - 6.4e-21 74.0 0.0 2.9e-20 71.9 0.0 2.1 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HA2 PF04408.23 OAJ18020.1 - 1.2e-23 83.4 0.1 3.9e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ18020.1 - 6.7e-21 74.4 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ18020.1 - 2.4e-13 50.4 0.0 5.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ18020.1 - 0.00013 22.3 0.1 0.00031 21.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAJ18020.1 - 0.00027 20.1 0.0 0.0007 18.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 OAJ18020.1 - 0.0008 19.2 0.3 0.0024 17.7 0.3 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ18020.1 - 0.0024 17.6 0.0 0.0024 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ18020.1 - 0.0072 16.7 0.1 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAJ18020.1 - 0.032 14.8 0.2 0.43 11.1 0.1 2.4 1 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 OAJ18020.1 - 0.098 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DAD PF02109.16 OAJ18021.1 - 9.7e-45 151.4 3.1 1.3e-44 150.9 3.1 1.2 1 0 0 1 1 1 1 DAD family Mucin PF01456.17 OAJ18021.1 - 0.011 15.8 14.2 0.017 15.1 14.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MDFI PF15316.6 OAJ18021.1 - 0.11 12.6 0.4 0.13 12.4 0.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor NUDE_C PF04880.13 OAJ18021.1 - 3.6 8.0 14.4 5.1 7.5 14.4 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region TadE PF07811.12 OAJ18021.1 - 4 7.8 7.0 1.1 9.6 0.4 2.8 3 0 0 3 3 3 0 TadE-like protein ATP19 PF11022.8 OAJ18022.1 - 7.3e-20 71.1 0.1 8.8e-20 70.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Cyt-b5 PF00173.28 OAJ18023.1 - 1.1e-18 67.1 0.0 1.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3530 PF12048.8 OAJ18023.1 - 5 6.4 11.5 6.2 6.1 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Peptidase_M28 PF04389.17 OAJ18024.1 - 5.4e-25 88.3 0.0 1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAJ18024.1 - 0.012 15.4 0.0 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 DPM2 PF07297.12 OAJ18025.1 - 2.4e-28 98.3 0.3 2.7e-28 98.1 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAJ18025.1 - 4.9e-05 23.2 0.1 5.5e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 PIG-P FecCD PF01032.18 OAJ18025.1 - 0.013 14.6 0.4 0.018 14.0 0.4 1.3 1 1 0 1 1 1 0 FecCD transport family ApbA PF02558.16 OAJ18025.1 - 0.053 13.2 0.1 0.075 12.7 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1206 PF06724.11 OAJ18025.1 - 1 9.5 7.4 3.4 7.8 0.8 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Bac_surface_Ag PF01103.23 OAJ18026.1 - 2.3e-32 112.8 1.3 4.3e-32 111.9 1.3 1.4 1 1 0 1 1 1 1 Surface antigen Pex24p PF06398.11 OAJ18027.1 - 8.9e-06 24.9 0.3 1.4e-05 24.3 0.3 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin PRCC PF10253.9 OAJ18028.1 - 4.5e-13 50.5 6.1 4.5e-13 50.5 6.1 2.2 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF5629 PF18629.1 OAJ18028.1 - 0.12 12.9 1.5 0.79 10.3 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5629) Paf1 PF03985.13 OAJ18030.1 - 1.6e-43 149.3 44.5 3.7e-23 82.2 0.0 5.3 3 2 1 5 5 5 4 Paf1 JAB PF01398.21 OAJ18031.1 - 2.5e-28 98.4 0.2 3.9e-28 97.8 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAJ18031.1 - 9.8e-16 58.5 4.6 4.2e-14 53.2 4.6 2.6 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAJ18031.1 - 6.8e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 OAJ18031.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) EVC2_like PF12297.8 OAJ18031.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein NUDIX PF00293.28 OAJ18032.1 - 0.49 10.4 5.5 0.68 10.0 4.3 1.8 1 1 1 2 2 2 0 NUDIX domain CRIM PF16978.5 OAJ18033.1 - 1e-30 106.7 0.0 2.3e-27 95.9 0.0 2.7 3 0 0 3 3 3 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAJ18033.1 - 5.8e-20 71.6 0.0 9.4e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Kei1 PF08552.11 OAJ18034.1 - 8.9e-52 175.7 0.2 1.1e-51 175.4 0.2 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Abhydrolase_6 PF12697.7 OAJ18035.1 - 3.4e-22 80.1 0.1 5.7e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ18035.1 - 9.9e-09 34.8 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ18035.1 - 6.1e-07 29.4 0.0 4.5e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF900 PF05990.12 OAJ18035.1 - 0.058 12.9 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 OAJ18035.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) SF3b10 PF07189.11 OAJ18036.1 - 1.7e-31 108.1 0.0 2e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) UQ_con PF00179.26 OAJ18038.1 - 5.8e-15 55.2 0.0 8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TrkA_TMD PF18613.1 OAJ18038.1 - 0.19 11.2 1.2 0.47 9.9 1.2 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain MFS_1 PF07690.16 OAJ18039.1 - 1.5e-18 66.9 13.8 1.5e-18 66.9 13.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.9 OAJ18039.1 - 0.29 10.8 1.3 0.63 9.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MFS_1_like PF12832.7 OAJ18039.1 - 0.46 9.3 21.3 2 7.1 4.9 2.8 2 1 0 2 2 2 0 MFS_1 like family DTHCT PF08070.11 OAJ18040.1 - 0.17 12.7 9.9 0.053 14.2 6.6 1.8 2 0 0 2 2 2 0 DTHCT (NUC029) region SWIRM-assoc_2 PF16496.5 OAJ18040.1 - 0.71 8.7 4.5 1.8 7.3 4.3 1.6 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal DJ-1_PfpI PF01965.24 OAJ18041.1 - 5.6e-39 133.6 0.0 6.5e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 OAJ18041.1 - 7.7e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases MtmB PF05369.12 OAJ18041.1 - 0.038 12.8 0.1 0.047 12.5 0.1 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB His_biosynth PF00977.21 OAJ18043.1 - 4.3e-41 140.9 0.1 2.8e-38 131.7 0.1 2.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 OAJ18043.1 - 8.7e-17 61.5 0.0 1.5e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 OAJ18043.1 - 2.8e-08 33.8 0.0 1.5e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAJ18043.1 - 3.2e-08 33.4 0.0 7.3e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 OAJ18043.1 - 0.12 12.1 0.4 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 Peptidase_S51 PF03575.17 OAJ18043.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 MFS_1 PF07690.16 OAJ18044.1 - 3.9e-17 62.2 14.4 5.7e-17 61.7 14.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 OAJ18044.1 - 0.00093 18.6 4.3 0.0013 18.1 4.3 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAJ18044.1 - 0.026 13.4 7.6 0.036 12.9 7.6 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ18044.1 - 0.13 11.1 6.2 0.2 10.5 6.2 1.2 1 0 0 1 1 1 0 MFS_1 like family Asp PF00026.23 OAJ18045.1 - 3.8e-61 207.2 0.5 4.8e-61 206.9 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ18045.1 - 3.9e-13 50.0 7.5 2.3e-12 47.5 4.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal OTOS PF15182.6 OAJ18045.1 - 0.045 13.7 1.8 0.11 12.5 0.5 2.2 2 0 0 2 2 2 0 Otospiralin AMP-binding PF00501.28 OAJ18046.1 - 3.6e-71 240.0 0.0 4.9e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ18046.1 - 7.4e-65 218.7 0.0 1.1e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 OAJ18046.1 - 1.4e-12 47.1 0.1 3.4e-10 39.2 0.0 3.4 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.25 OAJ18046.1 - 2.6e-11 43.7 0.0 6.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ18046.1 - 3.1e-06 26.8 0.0 6.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 OAJ18046.1 - 0.00016 22.6 0.0 0.00092 20.1 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OAJ18046.1 - 0.0002 20.4 0.0 0.011 14.7 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CENP-B_dimeris PF09026.10 OAJ18046.1 - 0.037 14.4 1.2 0.079 13.4 1.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EF-hand_7 PF13499.6 OAJ18048.1 - 1.6e-27 95.8 10.8 7.9e-15 55.1 3.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAJ18048.1 - 1e-26 90.4 15.5 2e-08 33.2 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ18048.1 - 5.2e-23 79.0 9.8 3.4e-07 29.6 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ18048.1 - 3.6e-15 55.6 13.1 2.6e-08 33.6 1.7 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ18048.1 - 8.8e-12 44.0 10.9 7.8e-05 22.0 1.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OAJ18048.1 - 2.1e-09 37.5 0.6 0.0021 18.3 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ18048.1 - 4.3e-06 26.6 2.5 0.019 14.9 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OAJ18048.1 - 9e-05 22.5 1.1 0.075 13.0 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein SurA_N_2 PF13623.6 OAJ18048.1 - 0.052 13.4 1.4 0.84 9.5 0.3 2.2 2 0 0 2 2 2 0 SurA N-terminal domain PhetRS_B1 PF18262.1 OAJ18048.1 - 0.078 13.2 1.3 0.18 12.0 1.3 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_14 PF17959.1 OAJ18048.1 - 0.082 13.3 1.7 1.3 9.4 0.4 2.2 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ18048.1 - 0.1 12.9 1.1 7.6 6.9 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1636 PF07845.11 OAJ18048.1 - 0.18 12.2 0.0 3.2 8.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) PTPlike_phytase PF14566.6 OAJ18049.1 - 0.0004 20.5 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 OAJ18049.1 - 0.001 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAJ18049.1 - 0.003 17.6 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ18049.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NIF PF03031.18 OAJ18065.1 - 1.7e-06 27.9 0.0 0.021 14.6 0.0 3.1 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase RNase_H2_suC PF08615.11 OAJ18065.1 - 0.039 14.1 0.0 0.24 11.6 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RVT_1 PF00078.27 OAJ18067.1 - 4.4e-25 88.5 0.0 7.5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ18067.1 - 1e-15 57.5 0.1 2e-15 56.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ18067.1 - 1.2e-13 50.9 0.0 4.6e-12 45.8 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ18067.1 - 6.4e-06 26.4 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ18067.1 - 0.00029 21.1 0.0 0.0089 16.3 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase dUTPase PF00692.19 OAJ18067.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 dUTPase Glyco_hydro_88 PF07470.13 OAJ18068.1 - 1.9e-11 43.6 0.3 1.3e-10 40.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Npa1 PF11707.8 OAJ18071.1 - 2.1e-75 254.2 0.0 7.1e-46 157.1 0.0 3.0 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAJ18071.1 - 1.1e-44 152.5 1.2 1.1e-44 152.5 1.2 2.0 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Pox_Ag35 PF03286.14 OAJ18071.1 - 0.53 10.0 2.6 1.4 8.7 2.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2520 PF10728.9 OAJ18071.1 - 9.3 6.0 10.0 6.4 6.6 0.2 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF2520) Lactonase PF10282.9 OAJ18073.1 - 6.7e-65 219.6 0.1 7.6e-65 219.4 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RRM_1 PF00076.22 OAJ18074.1 - 7.5e-38 128.2 0.0 7e-17 61.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.12 OAJ18074.1 - 0.0083 15.9 29.6 0.0083 15.9 29.6 2.3 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 OAJ18074.1 - 0.013 13.6 11.0 0.034 12.3 11.0 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CNDH2_C PF16858.5 OAJ18074.1 - 0.036 13.9 15.8 0.043 13.7 11.7 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Afi1 PF07792.12 OAJ18074.1 - 1.7 9.1 13.1 6.2 7.3 13.1 2.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFIIA PF03153.13 OAJ18074.1 - 2.7 7.9 21.9 6.2 6.7 21.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 OAJ18074.1 - 2.9 7.0 7.6 0.81 8.8 4.4 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter NOA36 PF06524.12 OAJ18074.1 - 3.3 7.0 30.1 6.7 5.9 30.1 1.5 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 OAJ18074.1 - 6.8 5.6 9.4 14 4.5 9.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Complex1_49kDa PF00346.19 OAJ18075.1 - 1.2e-121 405.0 0.0 1.5e-121 404.7 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 OAJ18075.1 - 0.0024 16.9 0.0 0.0039 16.1 0.0 1.4 1 1 0 1 1 1 1 Nickel-dependent hydrogenase GNAT_acetyltr_2 PF13718.6 OAJ18077.1 - 8.5e-75 251.0 0.0 1.4e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 OAJ18077.1 - 8.9e-51 172.2 0.0 1.4e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 OAJ18077.1 - 2.1e-50 171.6 0.0 2.4e-48 164.9 0.0 2.2 1 1 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 OAJ18077.1 - 2.3e-28 97.9 0.0 5.8e-28 96.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Endonuclease_NS PF01223.23 OAJ18078.1 - 2.7e-52 177.8 0.0 1.5e-50 172.2 0.0 2.1 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease CAP PF00188.26 OAJ18080.1 - 7.7e-18 65.5 0.2 7.7e-18 65.5 0.2 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Otopetrin PF03189.13 OAJ18080.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 OAJ18080.1 - 0.29 10.3 10.7 0.46 9.7 10.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4666 PF15697.5 OAJ18080.1 - 0.52 11.0 4.7 40 5.0 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) RR_TM4-6 PF06459.12 OAJ18080.1 - 0.99 9.2 5.8 1.9 8.3 5.8 1.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAJ18080.1 - 2.3 6.9 4.4 3.7 6.2 4.4 1.3 1 0 0 1 1 1 0 Presenilin Ctr PF04145.15 OAJ18080.1 - 2.9 8.5 4.2 57 4.3 2.9 2.1 2 0 0 2 2 2 0 Ctr copper transporter family TF_Zn_Ribbon PF08271.12 OAJ18081.1 - 0.017 14.7 1.3 0.037 13.5 1.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding NOT2_3_5 PF04153.18 OAJ18082.1 - 1.8e-33 115.4 2.4 2.9e-33 114.7 2.4 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family UBA2_C PF16195.5 OAJ18082.1 - 0.037 14.7 1.4 0.082 13.6 1.4 1.6 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus API5 PF05918.11 OAJ18082.1 - 1.6 7.4 7.1 2 7.2 7.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_M50 PF02163.22 OAJ18083.1 - 2e-08 33.8 3.4 0.0029 16.9 0.1 3.0 1 1 1 2 2 2 2 Peptidase family M50 BRO1 PF03097.18 OAJ18084.1 - 1e-108 363.6 0.0 2e-108 362.7 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ18084.1 - 5.1e-48 163.9 15.8 7.4e-48 163.3 15.8 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2673 PF10880.8 OAJ18084.1 - 0.13 12.4 0.0 0.53 10.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) Kinesin_assoc PF16183.5 OAJ18084.1 - 1.7 8.7 7.2 0.93 9.6 4.4 2.0 2 0 0 2 2 2 0 Kinesin-associated zf-C2H2 PF00096.26 OAJ18085.1 - 0.00047 20.5 0.0 0.0017 18.7 0.0 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 OAJ18085.1 - 0.028 14.2 0.6 0.073 12.9 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 OAJ18085.1 - 0.033 15.0 0.0 0.11 13.4 0.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Na_Ca_ex PF01699.24 OAJ18086.1 - 1.3e-43 148.5 45.8 6.4e-26 91.1 15.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein MLANA PF14991.6 OAJ18086.1 - 0.11 12.8 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein melan-A AveC_like PF17198.4 OAJ18086.1 - 0.39 10.1 5.8 0.1 12.0 1.9 1.9 2 0 0 2 2 2 0 Spirocyclase AveC-like Lactonase PF10282.9 OAJ18087.1 - 3.2e-67 227.2 0.0 3.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller P4Ha_N PF08336.11 OAJ18101.1 - 0.0068 16.4 1.3 0.01 15.8 1.3 1.2 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3016 PF11454.8 OAJ18103.1 - 0.08 12.7 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) F-box-like PF12937.7 OAJ18104.1 - 1.2e-09 37.9 3.8 0.0007 19.4 0.0 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 OAJ18104.1 - 0.01 15.7 5.7 0.9 9.5 0.0 4.1 4 0 0 4 4 4 0 F-box domain F-box PF00646.33 OAJ18106.1 - 0.0092 15.8 0.2 0.057 13.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain Lipase_GDSL PF00657.22 OAJ18107.1 - 4.5e-07 30.0 0.0 5.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAJ18107.1 - 0.0011 19.4 1.7 0.0031 17.9 0.9 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Jacalin PF01419.17 OAJ18108.1 - 1.4e-06 28.3 1.2 0.0028 17.6 0.1 2.9 2 1 0 2 2 2 2 Jacalin-like lectin domain Jacalin PF01419.17 OAJ18109.1 - 0.00014 21.8 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 Jacalin-like lectin domain COG2 PF06148.11 OAJ18109.1 - 0.16 12.1 2.6 20 5.3 0.0 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NUDE_C PF04880.13 OAJ18111.1 - 0.094 13.2 1.7 0.095 13.2 1.7 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PAN_1 PF00024.26 OAJ18112.1 - 0.00043 20.2 0.4 0.0015 18.4 0.4 1.9 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 OAJ18112.1 - 0.00063 19.6 0.8 0.0014 18.5 0.8 1.5 1 0 0 1 1 1 1 PAN domain SKICH PF17751.1 OAJ18112.1 - 0.019 15.5 0.0 0.7 10.5 0.0 2.5 2 0 0 2 2 2 0 SKICH domain DUF2644 PF10841.8 OAJ18113.1 - 0.049 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) Imm71 PF15602.6 OAJ18114.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 71 F-box PF00646.33 OAJ18116.1 - 3e-06 27.0 0.2 6.6e-06 25.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ18116.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 OAJ18116.1 - 0.006 16.5 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 OAJ18117.1 - 4.6e-07 29.5 0.3 1.6 9.0 0.0 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18117.1 - 1.1e-06 28.8 5.9 0.037 14.3 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18117.1 - 0.00013 21.6 0.0 0.52 10.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18117.1 - 0.0056 17.3 11.8 4.5 8.0 0.2 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18117.1 - 0.08 13.2 0.0 9.5 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 OAJ18119.1 - 0.024 14.5 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 OAJ18122.1 - 0.072 13.0 0.2 0.32 10.9 0.2 2.1 1 0 0 1 1 1 0 F-box domain H_lectin PF09458.10 OAJ18123.1 - 1.8e-11 44.0 0.0 9.3e-07 29.0 0.0 3.2 3 0 0 3 3 3 2 H-type lectin domain Cupin_1 PF00190.22 OAJ18125.1 - 3.3e-30 104.7 0.1 3.9e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAJ18125.1 - 2.4e-20 72.0 0.5 1.9e-15 56.3 0.0 2.5 3 0 0 3 3 3 2 Cupin domain AraC_binding PF02311.19 OAJ18125.1 - 3.6e-07 30.2 0.3 0.00078 19.4 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAJ18125.1 - 6.1e-05 22.6 0.0 0.0053 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 OAJ18125.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PemK_toxin PF02452.17 OAJ18125.1 - 0.026 14.9 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Cupin_7 PF12973.7 OAJ18125.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 ChrR Cupin-like domain Ectoine_synth PF06339.12 OAJ18125.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Ectoine synthase DAHP_synth_1 PF00793.20 OAJ18141.1 - 5.9e-101 336.9 0.0 7.6e-101 336.6 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DUF1522 PF07482.11 OAJ18141.1 - 0.049 13.9 0.5 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) Acetyltransf_8 PF13523.6 OAJ18142.1 - 2.2e-37 128.0 1.4 3.2e-37 127.4 1.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rcd1 PF04078.13 OAJ18143.1 - 4.2e-122 406.4 1.0 5.4e-122 406.1 1.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like DNase_NucA_NucB PF14040.6 OAJ18144.1 - 0.00014 22.2 1.0 0.00014 22.2 1.0 3.2 2 2 1 3 3 3 1 Deoxyribonuclease NucA/NucB RskA PF10099.9 OAJ18144.1 - 6.4 7.0 12.4 14 5.9 12.4 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA F-box-like PF12937.7 OAJ18145.1 - 7.8e-05 22.5 0.1 0.00024 20.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ18145.1 - 0.11 12.4 0.1 2 8.4 0.0 2.5 2 0 0 2 2 2 0 F-box domain RMF PF04957.12 OAJ18145.1 - 0.51 10.6 3.8 3.4 8.0 0.4 2.4 1 1 1 2 2 2 0 Ribosome modulation factor RMI1_N PF08585.12 OAJ18146.1 - 3.1e-40 138.3 0.0 3.9e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein DUF1180 PF06679.12 OAJ18146.1 - 0.023 15.1 0.7 0.039 14.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1917 PF08939.10 OAJ18147.1 - 2.5e-14 53.8 0.4 2.5e-14 53.8 0.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Mog1 PF04603.12 OAJ18148.1 - 5.9e-40 136.8 0.0 7e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein IMPDH PF00478.25 OAJ18149.1 - 8.4e-133 442.6 0.0 1e-131 439.1 0.0 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAJ18149.1 - 1.5e-17 63.8 0.1 4.3e-09 36.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 OAJ18149.1 - 9.5e-11 41.7 4.2 6.9e-08 32.2 2.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAJ18149.1 - 1.8e-10 40.4 1.4 3.5e-10 39.5 0.5 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAJ18149.1 - 1.6e-07 31.1 3.3 5.7e-06 26.0 0.7 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAJ18149.1 - 0.00041 19.7 2.3 0.00041 19.7 2.3 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 OAJ18149.1 - 0.00047 19.4 0.2 0.0015 17.8 0.2 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.19 OAJ18149.1 - 0.0094 15.4 0.5 0.047 13.1 0.0 2.2 2 0 0 2 2 2 1 KDPG and KHG aldolase G3P_antiterm PF04309.12 OAJ18149.1 - 0.012 15.0 0.8 0.51 9.7 0.2 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 OAJ18149.1 - 0.038 13.2 0.1 0.67 9.1 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase YpsA PF06908.11 OAJ18149.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Dus PF01207.17 OAJ18149.1 - 0.078 12.1 1.7 0.51 9.4 0.1 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PK PF00224.21 OAJ18149.1 - 0.092 11.6 0.0 0.2 10.5 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF561 PF04481.12 OAJ18149.1 - 0.15 11.2 1.2 0.72 9.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) SPC12 PF06645.13 OAJ18151.1 - 4.9e-26 90.6 0.2 5.8e-26 90.4 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MutS_V PF00488.21 OAJ18152.1 - 1.8e-80 269.4 0.1 2.9e-80 268.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ18152.1 - 5.3e-36 124.6 0.4 5.3e-36 124.6 0.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAJ18152.1 - 6.9e-19 68.0 0.7 2.4e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 OAJ18152.1 - 1.3e-15 57.6 0.0 3.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ18152.1 - 1.6e-15 57.6 0.0 5.6e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 MutS domain II NAT PF04768.13 OAJ18153.1 - 1.3e-45 155.1 0.0 2.2e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 OAJ18153.1 - 3.7e-30 105.3 0.6 1.4e-29 103.4 0.0 2.3 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 OAJ18153.1 - 1.9e-24 86.4 0.0 4.5e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 OAJ18153.1 - 1.6e-10 41.4 0.0 4.1e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 OAJ18153.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.13 OAJ18153.1 - 0.45 10.5 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Pam16 CorA PF01544.18 OAJ18155.1 - 2.8e-20 72.8 0.7 6e-07 29.1 0.3 3.4 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Thioredoxin PF00085.20 OAJ18156.1 - 1.9e-25 88.8 0.0 7.1e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OAJ18156.1 - 2.5e-08 33.6 0.0 3.7e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ18156.1 - 0.00074 19.8 0.0 0.01 16.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ18156.1 - 0.0022 18.4 0.0 0.0061 17.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ18156.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 OAJ18156.1 - 0.057 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family GHMP_kinases_N PF00288.26 OAJ18156.1 - 0.086 13.1 0.8 0.19 12.0 0.8 1.8 1 1 0 1 1 1 0 GHMP kinases N terminal domain MS_channel PF00924.18 OAJ18157.1 - 5.2e-05 22.9 0.0 6.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Phage_endo_I PF05367.11 OAJ18157.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phage endonuclease I ING PF12998.7 OAJ18158.1 - 9.9e-09 35.7 0.0 3.6e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ18158.1 - 0.00012 21.8 7.2 0.00019 21.2 7.2 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ18158.1 - 0.019 14.5 1.7 0.034 13.7 1.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.8 OAJ18158.1 - 0.074 13.4 0.5 0.14 12.5 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-HC5HC2H PF13771.6 OAJ18158.1 - 0.22 11.8 2.8 0.46 10.8 2.8 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain SDA1 PF05285.12 OAJ18159.1 - 5.3e-05 22.8 19.5 9.3e-05 22.0 19.5 1.4 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OAJ18159.1 - 0.00053 19.5 19.2 0.00097 18.6 19.2 1.5 1 0 0 1 1 1 1 BUD22 Sec20 PF03908.13 OAJ18160.1 - 2.9e-21 75.2 1.7 9.3e-21 73.6 1.7 1.9 1 0 0 1 1 1 1 Sec20 CCDC-167 PF15188.6 OAJ18160.1 - 0.71 10.3 3.8 4.9 7.6 1.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SDA1 PF05285.12 OAJ18161.1 - 1.7e-05 24.5 11.8 1.7e-05 24.5 11.8 3.0 3 1 0 3 3 3 1 SDA1 bZIP_1 PF00170.21 OAJ18161.1 - 5e-05 23.3 22.2 0.0032 17.5 13.1 2.5 2 0 0 2 2 2 2 bZIP transcription factor Syntaxin PF00804.25 OAJ18161.1 - 0.0051 16.5 0.4 0.011 15.4 0.4 1.5 1 0 0 1 1 1 1 Syntaxin ZapB PF06005.12 OAJ18161.1 - 0.0065 16.9 1.3 0.0065 16.9 1.3 2.5 3 0 0 3 3 3 1 Cell division protein ZapB YabA PF06156.13 OAJ18161.1 - 0.028 15.0 0.3 0.089 13.4 0.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA UPF0242 PF06785.11 OAJ18161.1 - 0.03 14.4 0.0 0.03 14.4 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus eIF-3c_N PF05470.12 OAJ18161.1 - 0.08 11.2 4.6 0.1 10.9 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus bZIP_2 PF07716.15 OAJ18161.1 - 0.43 10.7 29.9 0.13 12.4 14.7 3.3 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_Maf PF03131.17 OAJ18161.1 - 8.4 7.0 16.6 21 5.7 1.8 2.8 2 0 0 2 2 2 0 bZIP Maf transcription factor MS_channel PF00924.18 OAJ18162.1 - 8.7e-15 54.8 0.3 2.1e-14 53.6 0.3 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAJ18162.1 - 3.8e-05 22.9 0.1 8.6e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ18162.1 - 0.00011 21.8 0.0 0.00031 20.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAJ18162.1 - 0.00022 21.6 0.1 0.00049 20.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAJ18162.1 - 0.05 13.1 0.2 0.12 11.9 0.2 1.5 1 0 0 1 1 1 0 EF hand MS_channel PF00924.18 OAJ18163.1 - 2.4e-08 33.8 6.1 3.8e-08 33.1 6.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAJ18163.1 - 0.0022 17.4 0.0 0.0062 16.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ18163.1 - 0.003 17.3 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 OAJ18163.1 - 0.042 13.3 0.1 0.095 12.2 0.1 1.6 1 0 0 1 1 1 0 EF hand ADH_N PF08240.12 OAJ18164.1 - 9.8e-10 38.3 0.7 1.3e-08 34.7 0.7 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ18164.1 - 1.9e-09 37.6 0.0 4.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ18164.1 - 3.4e-06 28.1 0.0 8.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Coatomer_WDAD PF04053.14 OAJ18164.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Zn_clus PF00172.18 OAJ18165.1 - 1.5e-07 31.4 5.4 2.5e-07 30.7 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ18165.1 - 5.5e-06 25.6 0.1 1.1e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Siva PF05458.12 OAJ18165.1 - 0.073 12.7 1.2 0.17 11.5 1.2 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Tub_N PF16322.5 OAJ18165.1 - 3.6 7.9 5.4 0.58 10.5 0.3 2.1 2 1 0 2 2 2 0 Tubby N-terminal Ribonuc_2-5A PF06479.12 OAJ18182.1 - 5.8e-40 136.4 0.0 9e-40 135.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 OAJ18182.1 - 1.7e-38 132.5 0.0 3.7e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18182.1 - 1.3e-19 70.5 0.0 6.9e-16 58.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ18182.1 - 0.0002 20.3 0.0 0.00065 18.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAJ18182.1 - 0.0002 20.8 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 OAJ18182.1 - 0.0043 16.7 0.4 0.36 10.4 0.0 3.1 4 0 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 OAJ18182.1 - 0.0048 16.8 0.1 0.058 13.3 0.1 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat FUSC_2 PF13515.6 OAJ18183.1 - 6.3e-17 61.9 16.9 6.3e-17 61.9 16.9 3.0 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 OAJ18183.1 - 4.1e-13 49.2 11.9 8e-08 31.7 0.1 4.0 4 0 0 4 4 4 3 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 OAJ18183.1 - 2.1e-09 36.5 9.5 2.1e-09 36.5 9.5 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 OAJ18183.1 - 1.3e-06 27.6 8.1 1.3e-06 27.6 8.1 3.0 3 1 0 3 3 3 1 Aluminium activated malate transporter ArAE_2 PF10334.9 OAJ18183.1 - 0.0004 20.3 1.2 0.0004 20.3 1.2 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 OAJ18183.1 - 0.00041 20.5 6.1 0.0011 19.1 6.1 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 MbeB_N PF04837.12 OAJ18183.1 - 0.44 10.9 2.1 1 9.7 0.2 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region WD40 PF00400.32 OAJ18184.1 - 9.5e-05 23.1 13.2 0.28 12.1 0.2 5.9 6 1 0 6 6 6 2 WD domain, G-beta repeat PQQ_2 PF13360.6 OAJ18184.1 - 0.0013 18.4 0.1 0.02 14.5 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 OAJ18184.1 - 0.0021 18.5 4.4 2.6 8.6 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain BUD22 PF09073.10 OAJ18184.1 - 0.17 11.2 29.1 0.23 10.8 27.2 1.9 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 OAJ18184.1 - 1.1 7.4 23.9 1.6 6.8 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ18184.1 - 1.2 8.4 24.3 3 7.2 24.3 1.5 1 0 0 1 1 1 0 SDA1 BHD_2 PF10404.9 OAJ18184.1 - 1.7 9.7 4.3 3 8.9 1.8 2.7 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF3368 PF11848.8 OAJ18186.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) EF_TS PF00889.19 OAJ18187.1 - 1.9e-13 50.5 0.0 7.8e-12 45.3 0.0 3.0 3 2 0 3 3 3 1 Elongation factor TS NAD_binding_4 PF07993.12 OAJ18188.1 - 5.3e-23 81.5 0.0 9.6e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAJ18188.1 - 3.9e-16 58.7 0.0 1.4e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 OAJ18188.1 - 5.4e-16 58.8 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ18188.1 - 5.7e-06 26.0 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 OAJ18188.1 - 0.0002 21.4 0.1 0.0007 19.5 0.1 1.9 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 OAJ18188.1 - 0.00097 18.2 0.0 0.002 17.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Gcd10p PF04189.13 OAJ18188.1 - 0.051 12.7 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family Polysacc_synt_2 PF02719.15 OAJ18188.1 - 0.092 11.9 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DTHCT PF08070.11 OAJ18190.1 - 0.016 16.0 2.1 0.016 16.0 2.1 4.2 3 2 1 4 4 4 0 DTHCT (NUC029) region Peptidase_M28 PF04389.17 OAJ18191.1 - 3.3e-37 128.1 0.0 5e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SMC_N PF02463.19 OAJ18192.1 - 1.9e-22 79.8 0.0 3.8e-22 78.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ18192.1 - 5e-20 72.9 0.0 5e-20 72.9 0.0 5.3 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 OAJ18192.1 - 2.2e-09 37.5 0.0 2.2e-09 37.5 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAJ18192.1 - 2e-05 24.6 2.3 0.00017 21.5 0.0 3.1 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ18192.1 - 2.5e-05 23.9 0.0 0.00017 21.3 0.0 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 OAJ18192.1 - 0.039 14.4 1.9 1.1 9.7 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 OAJ18192.1 - 0.09 13.3 0.0 0.09 13.3 0.0 5.2 3 2 0 3 3 3 0 ABC transporter CLP1_P PF16575.5 OAJ18193.1 - 1e-25 90.6 0.0 1.3e-21 77.2 0.0 3.0 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OAJ18193.1 - 3.3e-23 82.3 0.0 5.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OAJ18193.1 - 1.2e-17 63.9 0.0 2.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor MMR_HSR1 PF01926.23 OAJ18193.1 - 0.047 13.8 0.1 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAJ18193.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pro_CA PF00484.19 OAJ18193.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase Dynamin_N PF00350.23 OAJ18193.1 - 0.15 12.1 0.2 0.35 10.9 0.2 1.6 2 0 0 2 2 2 0 Dynamin family SurE PF01975.17 OAJ18194.1 - 2.7e-41 141.5 0.0 1.8e-40 138.8 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE PAM2 PF07145.15 OAJ18195.1 - 0.12 12.1 0.6 27 4.7 0.1 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region LisH PF08513.11 OAJ18196.1 - 0.0004 20.2 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 OAJ18197.1 - 8.4e-61 206.0 0.0 1.1e-60 205.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAJ18197.1 - 4.9e-35 121.3 0.2 2.8e-34 118.8 0.2 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal CitMHS PF03600.16 OAJ18198.1 - 2.2e-14 53.3 5.5 2.2e-14 53.3 5.5 1.8 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 OAJ18198.1 - 7.8e-11 41.9 17.6 5.7e-06 25.9 6.7 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF4449 PF14613.6 OAJ18199.1 - 0.0043 17.2 0.3 0.0043 17.2 0.3 5.0 3 2 0 3 3 3 1 Protein of unknown function (DUF4449) ATP13 PF12921.7 OAJ18199.1 - 0.0067 16.3 0.1 0.53 10.2 0.0 2.7 1 1 1 2 2 2 2 Mitochondrial ATPase expression AAA_6 PF12774.7 OAJ18199.1 - 0.01 14.9 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Mad3_BUB1_I PF08311.12 OAJ18199.1 - 0.012 15.6 0.3 4.4 7.3 0.1 2.6 1 1 0 2 2 2 0 Mad3/BUB1 homology region 1 Ribosomal_60s PF00428.19 OAJ18199.1 - 0.036 14.6 3.1 0.043 14.4 0.1 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PilO PF04350.13 OAJ18199.1 - 0.27 11.4 5.6 1.4 9.1 0.9 2.8 2 0 0 2 2 2 0 Pilus assembly protein, PilO SseC PF04888.12 OAJ18199.1 - 3.4 7.2 7.3 8.4 5.9 0.1 3.5 3 1 0 3 3 3 0 Secretion system effector C (SseC) like family DUF445 PF04286.12 OAJ18199.1 - 5 6.8 20.8 1.1 9.1 11.5 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF445) Coatomer_WDAD PF04053.14 OAJ18200.1 - 1.3e-145 485.9 0.0 3.3e-145 484.6 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 OAJ18200.1 - 1.1e-36 124.1 9.0 4.5e-07 30.5 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18200.1 - 5.8e-10 39.3 0.1 0.065 13.5 0.0 7.2 5 1 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ18200.1 - 0.003 16.3 1.6 1.4 7.5 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 OAJ18200.1 - 0.074 12.4 0.0 25 4.1 0.0 3.1 2 1 1 3 3 3 0 WD40-like domain DAO PF01266.24 OAJ18217.1 - 1.6e-23 83.9 2.1 5.1e-23 82.2 2.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase LigB PF02900.18 OAJ18217.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.24 OAJ18218.1 - 1.6e-78 264.6 20.8 2e-78 264.3 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ18218.1 - 6.6e-13 48.3 30.7 6.6e-13 48.3 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sin3a_C PF16879.5 OAJ18219.1 - 9.3e-75 252.0 0.0 9.3e-75 252.0 0.0 2.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 OAJ18219.1 - 6.9e-41 138.3 1.9 9.3e-41 137.9 0.2 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 OAJ18219.1 - 2.2e-39 133.4 19.2 3.1e-18 65.6 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Fructosamin_kin PF03881.14 OAJ18220.1 - 4.7e-60 203.2 0.0 5.3e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAJ18220.1 - 3.2e-09 37.1 0.0 4.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1b PF00579.25 OAJ18221.1 - 2.2e-21 76.5 0.0 4.8e-21 75.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-H2C2_2 PF13465.6 OAJ18223.1 - 2.2e-20 72.1 34.5 7.5e-06 26.2 0.7 7.4 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.26 OAJ18223.1 - 9e-16 57.4 52.1 0.00026 21.3 0.2 8.9 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ18223.1 - 5e-08 33.1 50.2 0.02 15.7 0.2 9.4 8 0 0 8 8 8 5 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ18223.1 - 0.00023 21.7 21.4 0.019 15.6 0.2 6.5 3 1 3 6 6 6 2 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 OAJ18223.1 - 0.12 12.2 0.0 0.12 12.2 0.0 7.3 8 0 0 8 8 8 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OAJ18223.1 - 0.15 12.1 0.1 0.15 12.1 0.1 5.0 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAJ18223.1 - 0.23 11.6 6.4 15 5.7 0.7 3.3 1 1 1 3 3 3 0 Aberrant zinc-finger zinc_ribbon_9 PF14369.6 OAJ18223.1 - 0.36 11.1 8.0 0.34 11.2 0.3 4.1 3 0 0 3 3 3 0 zinc-ribbon ABC1 PF03109.16 OAJ18224.1 - 4.1e-25 88.3 0.1 6.8e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family zf-4CXXC_R1 PF10497.9 OAJ18225.1 - 0.007 16.6 0.5 0.0085 16.3 0.5 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FOXP-CC PF16159.5 OAJ18226.1 - 0.011 16.4 0.1 0.024 15.3 0.1 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAJ18226.1 - 0.029 14.8 0.4 0.062 13.8 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Metallophos PF00149.28 OAJ18229.1 - 1.5e-39 136.6 0.0 2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ18229.1 - 4e-21 75.2 0.4 8.9e-21 74.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Bromodomain PF00439.25 OAJ18230.1 - 6.2e-21 74.3 0.0 1.1e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain TLP-20 PF06088.11 OAJ18230.1 - 6.6 6.6 6.8 1.1 9.1 1.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CDC45 PF02724.14 OAJ18230.1 - 7.9 4.6 8.0 0.18 10.0 0.8 1.7 2 0 0 2 2 2 0 CDC45-like protein Mcl1_mid PF12341.8 OAJ18231.1 - 2.7e-72 243.6 0.0 4.7e-71 239.6 0.0 2.3 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OAJ18231.1 - 9.6e-13 48.4 2.7 0.0021 18.8 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18231.1 - 4.7e-07 30.0 0.1 0.021 15.1 0.0 4.4 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 OAJ18231.1 - 0.12 12.3 0.1 0.48 10.3 0.0 2.0 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.6 OAJ18231.1 - 0.13 12.3 0.0 0.5 10.4 0.0 1.9 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Ferrochelatase PF00762.19 OAJ18232.1 - 2.6e-108 361.9 0.0 3.1e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 OAJ18232.1 - 0.00082 19.7 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 2 CbiX Piwi PF02171.17 OAJ18233.1 - 5.4e-78 262.3 0.0 8e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 OAJ18233.1 - 1.5e-15 56.6 0.0 3.8e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 OAJ18233.1 - 8.6e-15 55.6 0.0 2.1e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 OAJ18233.1 - 1.1e-10 41.6 0.1 3.2e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAJ18233.1 - 1.3e-10 41.4 0.0 2.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 OAJ18233.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain LSM PF01423.22 OAJ18234.1 - 5.1e-17 61.3 0.1 6.3e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF5497 PF17601.2 OAJ18234.1 - 0.031 14.6 0.0 0.04 14.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5497) SWIB PF02201.18 OAJ18235.1 - 2.4e-28 97.8 0.0 3.9e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAJ18235.1 - 9.1e-07 28.7 2.2 5.1e-06 26.3 0.7 2.6 3 0 0 3 3 3 1 DEK C terminal domain BC10 PF06726.12 OAJ18236.1 - 1.4e-11 44.5 10.4 2.4e-11 43.7 10.4 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Snapin_Pallidin PF14712.6 OAJ18236.1 - 0.14 12.6 1.5 0.25 11.8 1.5 1.4 1 0 0 1 1 1 0 Snapin/Pallidin DUF3138 PF11336.8 OAJ18236.1 - 0.19 10.3 4.8 0.59 8.7 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Malic_M PF03949.15 OAJ18237.1 - 2.7e-92 308.7 0.0 3.6e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAJ18237.1 - 2.1e-63 213.4 0.0 3.1e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF1631 PF07793.11 OAJ18252.1 - 0.35 9.2 4.6 0.035 12.5 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) SHE3 PF17078.5 OAJ18254.1 - 1.8e-07 31.1 3.3 1.8e-07 31.1 3.3 1.6 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 EzrA PF06160.12 OAJ18254.1 - 0.0041 15.4 3.0 0.51 8.4 0.0 2.2 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Filament PF00038.21 OAJ18254.1 - 0.022 14.4 22.3 0.62 9.6 5.3 3.1 2 1 1 3 3 3 0 Intermediate filament protein COG5 PF10392.9 OAJ18254.1 - 0.14 12.4 3.4 7 6.8 1.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.12 OAJ18254.1 - 0.14 12.1 5.0 0.15 12.1 3.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_CLD_2 PF14197.6 OAJ18254.1 - 0.16 12.1 16.7 0.02 14.9 6.8 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 SpoVAE PF14097.6 OAJ18254.1 - 0.17 11.6 0.7 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 Stage V sporulation protein AE1 DUF1664 PF07889.12 OAJ18254.1 - 0.3 11.1 3.6 1.6 8.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 OAJ18254.1 - 0.56 10.2 14.0 0.89 9.6 1.7 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 OAJ18254.1 - 0.58 8.3 8.9 0.039 12.1 2.4 2.0 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4407 PF14362.6 OAJ18254.1 - 0.79 9.0 17.0 0.021 14.2 4.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Muted PF14942.6 OAJ18254.1 - 1.1 9.6 4.2 0.57 10.5 0.5 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein MscS_porin PF12795.7 OAJ18254.1 - 1.8 8.1 25.2 0.023 14.2 10.9 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Golgin_A5 PF09787.9 OAJ18254.1 - 1.8 8.0 20.0 1 8.7 7.0 3.0 2 1 1 3 3 3 0 Golgin subfamily A member 5 THOC7 PF05615.13 OAJ18254.1 - 1.8 8.8 13.8 0.072 13.4 1.0 3.4 2 1 2 4 4 4 0 Tho complex subunit 7 Spc7 PF08317.11 OAJ18254.1 - 2.1 7.2 17.3 0.086 11.7 3.1 3.0 2 1 0 3 3 3 0 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 OAJ18254.1 - 3.2 8.3 12.2 2.2 8.8 0.9 3.9 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.11 OAJ18254.1 - 3.5 7.4 4.9 2.9 7.7 2.1 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.8 OAJ18254.1 - 4.7 7.3 15.3 0.047 13.8 4.9 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ERM PF00769.19 OAJ18254.1 - 5.1 6.8 25.1 13 5.5 23.1 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4201 PF13870.6 OAJ18254.1 - 7.6 6.2 10.6 0.32 10.7 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) CorA PF01544.18 OAJ18254.1 - 9.1 5.5 6.8 3.2 7.0 2.5 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 OAJ18254.1 - 9.7 6.1 7.1 6.4 6.7 0.3 2.9 2 1 1 3 3 3 0 Prefoldin subunit TAF8_C PF10406.9 OAJ18255.1 - 3.8e-08 33.8 10.6 3.5e-06 27.5 10.6 2.9 1 1 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term DUF3439 PF11921.8 OAJ18255.1 - 0.85 9.6 4.9 2.2 8.3 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) COPR5 PF15340.6 OAJ18256.1 - 0.13 12.9 0.3 0.65 10.6 0.0 2.2 2 0 0 2 2 2 0 Cooperator of PRMT5 family K_oxygenase PF13434.6 OAJ18257.1 - 2.6e-07 30.1 0.0 0.00096 18.4 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAJ18257.1 - 0.0023 17.2 0.8 1.4 8.1 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ18257.1 - 0.014 15.4 0.3 0.15 12.0 0.0 2.9 3 1 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAJ18257.1 - 0.15 11.1 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Nop53 PF07767.11 OAJ18257.1 - 4.1 6.7 14.3 0.51 9.7 6.7 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MSA-2c PF12238.8 OAJ18257.1 - 7.6 6.5 6.4 10 6.0 2.3 2.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c WD40 PF00400.32 OAJ18258.1 - 0.0017 19.2 0.1 0.26 12.2 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18258.1 - 0.0024 18.1 0.0 0.68 10.3 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HLH PF00010.26 OAJ18259.1 - 2.3e-13 49.9 0.0 1.4e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Synaptobrevin PF00957.21 OAJ18260.1 - 9.3e-15 54.2 0.9 1.5e-14 53.5 0.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAJ18260.1 - 4.9e-12 45.7 0.1 1.3e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Syntaxin-6_N PF09177.11 OAJ18260.1 - 0.025 15.1 0.2 0.044 14.3 0.2 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Ion_trans PF00520.31 OAJ18261.1 - 2.4e-132 439.6 84.9 6.7e-41 140.1 10.0 5.1 5 0 0 5 5 5 5 Ion transport protein UB2H PF14814.6 OAJ18261.1 - 0.13 12.3 0.0 0.49 10.4 0.0 2.0 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain IBR PF01485.21 OAJ18262.1 - 1.7e-20 73.0 49.2 4.8e-12 45.9 7.2 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAJ18262.1 - 0.00013 21.7 6.7 0.00013 21.7 6.7 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ18262.1 - 0.0049 16.9 2.8 0.0049 16.9 2.8 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ18262.1 - 0.01 16.1 5.8 0.01 16.1 5.8 4.0 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ18262.1 - 0.011 15.5 4.2 0.011 15.5 4.2 4.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.11 OAJ18262.1 - 7 6.6 9.2 13 5.8 0.6 2.8 2 1 0 2 2 2 0 Baculovirus U-box/Ring-like domain Cofilin_ADF PF00241.20 OAJ18263.1 - 5.8e-20 71.3 0.0 6.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GUCT PF08152.12 OAJ18263.1 - 0.093 13.0 0.1 0.26 11.6 0.1 1.8 1 1 0 1 1 1 0 GUCT (NUC152) domain TraX PF05857.11 OAJ18263.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 TraX protein MFS_1 PF07690.16 OAJ18264.1 - 2.4e-09 36.6 40.8 5.5e-08 32.1 34.5 3.4 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.25 OAJ18265.1 - 3.8e-22 78.7 0.0 1.4e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ18265.1 - 1.2e-17 64.3 0.0 1.9e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ18265.1 - 9e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAJ18265.1 - 0.0055 16.2 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ18265.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAJ18265.1 - 0.035 14.0 0.1 0.051 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ18265.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIB PF00382.19 OAJ18265.1 - 0.054 13.6 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 Transcription factor TFIIB repeat RabGAP-TBC PF00566.18 OAJ18266.1 - 9.1e-16 58.2 0.0 1.4e-05 24.8 0.0 3.9 3 1 0 3 3 3 3 Rab-GTPase-TBC domain AAA_lid_8 PF17868.1 OAJ18266.1 - 0.21 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain TetR_C_11 PF16859.5 OAJ18268.1 - 0.06 13.7 2.5 14 6.1 0.6 3.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF4449 PF14613.6 OAJ18268.1 - 1.6 8.8 8.2 0.2 11.8 1.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4449) zf_ZIC PF18366.1 OAJ18269.1 - 0.044 13.9 0.3 0.14 12.3 0.3 1.8 1 0 0 1 1 1 0 Zic proteins zinc finger domain zf_Hakai PF18408.1 OAJ18269.1 - 0.24 11.2 4.2 0.39 10.5 0.5 2.5 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain BROMI PF14961.6 OAJ18270.1 - 0.43 7.9 2.4 0.47 7.8 2.4 1.0 1 0 0 1 1 1 0 Broad-minded protein FAD_binding_3 PF01494.19 OAJ18271.1 - 5.4e-19 68.7 0.0 1.3e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ18271.1 - 3.9e-06 26.3 0.1 0.003 16.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAJ18271.1 - 0.00027 20.6 0.1 0.00047 19.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 OAJ18271.1 - 0.00058 20.0 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ18271.1 - 0.0007 20.1 0.2 0.0036 17.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ18271.1 - 0.0058 16.2 0.1 0.41 10.2 0.3 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 OAJ18271.1 - 0.008 15.3 0.0 0.04 13.0 0.0 2.0 2 1 1 3 3 3 1 Squalene epoxidase Methyltransf_25 PF13649.6 OAJ18273.1 - 1e-06 29.3 0.0 1.9e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ18273.1 - 2.7e-06 28.0 0.0 4.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ18273.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ18273.1 - 2.4e-05 24.9 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ18273.1 - 0.00013 21.9 0.0 0.00059 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain SH3BGR PF04908.15 OAJ18274.1 - 3.5e-14 52.8 0.0 6.8e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Ysc84 PF04366.12 OAJ18275.1 - 3.5e-40 136.7 0.0 3.5e-40 136.7 0.0 2.4 3 0 0 3 3 3 1 Las17-binding protein actin regulator VGCC_beta4Aa_N PF12052.8 OAJ18275.1 - 0.1 12.7 3.1 6 7.1 0.1 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF2721 PF11026.8 OAJ18295.1 - 0.65 9.9 2.7 1.1 9.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Velvet PF11754.8 OAJ18296.1 - 1e-33 117.3 1.1 7.1e-20 72.0 0.1 3.4 2 2 1 3 3 3 2 Velvet factor Flavoprotein PF02441.19 OAJ18298.1 - 6.8e-49 165.6 0.0 8.2e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Pkinase PF00069.25 OAJ18300.1 - 2.7e-39 135.2 0.0 3e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18300.1 - 3.4e-28 98.6 0.0 3.9e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ18300.1 - 1.8e-07 30.3 0.0 2.2e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ18300.1 - 0.00027 20.4 0.0 0.00044 19.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like UCH PF00443.29 OAJ18302.1 - 1.1e-31 110.3 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ18302.1 - 1.9e-06 27.7 0.0 2.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.20 OAJ18302.1 - 0.14 12.5 0.9 0.36 11.2 0.9 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat Velvet PF11754.8 OAJ18303.1 - 2e-28 100.0 0.1 3.2e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Velvet factor Exc PF07825.11 OAJ18303.1 - 0.11 12.5 0.2 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Excisionase-like protein MitMem_reg PF13012.6 OAJ18305.1 - 7.9e-35 119.7 0.2 1.4e-34 118.9 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAJ18305.1 - 1.5e-29 102.4 0.0 2.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3824 PF12868.7 OAJ18305.1 - 3.3 8.4 6.7 5.1 7.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AAA_33 PF13671.6 OAJ18307.1 - 5.3e-17 62.3 0.9 1.9e-14 54.0 0.9 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ18307.1 - 1.5e-08 34.2 0.0 4.7e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.10 OAJ18307.1 - 2.7e-06 27.0 1.5 0.00034 20.2 0.2 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 tRNA_lig_kinase PF08303.11 OAJ18307.1 - 6e-06 26.4 0.1 9.2e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 OAJ18307.1 - 0.00039 21.0 1.0 0.0099 16.4 1.0 2.2 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 OAJ18307.1 - 0.002 18.0 0.2 0.15 11.9 0.0 2.2 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 OAJ18307.1 - 0.015 15.7 1.3 0.94 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OAJ18307.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit APS_kinase PF01583.20 OAJ18307.1 - 0.022 14.6 0.1 0.055 13.4 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 OAJ18307.1 - 0.032 14.5 0.1 0.079 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 OAJ18307.1 - 0.08 13.1 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase 6PF2K PF01591.18 OAJ18307.1 - 0.12 11.7 0.1 1.2 8.4 0.2 2.3 2 1 0 2 2 2 0 6-phosphofructo-2-kinase Thymidylate_kin PF02223.17 OAJ18307.1 - 0.22 11.2 0.1 11 5.6 0.1 2.7 2 1 0 2 2 2 0 Thymidylate kinase Exo5 PF09810.9 OAJ18308.1 - 8.8e-37 127.4 11.3 1.3e-25 90.7 4.1 4.1 3 1 0 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease Aldo_ket_red PF00248.21 OAJ18309.1 - 6e-30 104.5 0.0 1.7e-29 103.0 0.0 1.7 2 0 0 2 2 2 1 Aldo/keto reductase family Far-17a_AIG1 PF04750.14 OAJ18310.1 - 7.6e-33 113.5 1.5 9.3e-33 113.3 1.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Syntaxin PF00804.25 OAJ18311.1 - 1.9e-26 93.0 13.1 1.9e-26 93.0 13.1 2.0 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 OAJ18311.1 - 0.00012 22.0 2.0 0.00012 22.0 2.0 3.3 4 0 0 4 4 4 1 SNARE domain Syntaxin_2 PF14523.6 OAJ18311.1 - 0.00068 20.0 7.3 0.00068 20.0 7.3 2.5 3 1 0 3 3 3 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 OAJ18311.1 - 0.15 12.7 11.1 0.93 10.1 2.0 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_14 PF13428.6 OAJ18311.1 - 0.19 12.7 1.7 2 9.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4231 PF14015.6 OAJ18311.1 - 0.2 12.2 0.1 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Muted PF14942.6 OAJ18311.1 - 1.2 9.4 18.0 0.043 14.1 5.8 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein TetR_C_11 PF16859.5 OAJ18311.1 - 6.3 7.1 7.4 0.68 10.3 1.7 2.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SLATT_6 PF18169.1 OAJ18311.1 - 8.9 5.9 7.2 2.4 7.7 1.2 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 HA2 PF04408.23 OAJ18312.1 - 1.2e-21 77.1 1.8 2.5e-21 76.0 0.0 2.6 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ18312.1 - 4.8e-15 55.7 0.0 1.3e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ18312.1 - 2.7e-13 50.2 0.0 6.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ18312.1 - 1.1e-08 35.1 0.1 2.2e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ18312.1 - 2.3e-06 27.9 0.1 5.4e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ18312.1 - 0.0012 18.6 1.2 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ18312.1 - 0.0016 18.8 0.1 0.0035 17.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAJ18312.1 - 0.0053 15.9 0.0 0.0099 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 OAJ18312.1 - 0.011 15.4 0.1 0.026 14.1 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OAJ18312.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 OAJ18312.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 OAJ18312.1 - 0.027 13.7 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 OAJ18312.1 - 0.034 14.3 0.1 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 OAJ18312.1 - 0.035 14.2 0.2 0.28 11.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ18312.1 - 0.039 14.3 0.1 0.16 12.4 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 OAJ18312.1 - 0.056 14.0 0.0 0.35 11.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 OAJ18312.1 - 0.1 12.8 2.6 0.14 12.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAJ18312.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 OAJ18312.1 - 0.11 11.9 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 OAJ18312.1 - 0.16 11.8 0.1 1 9.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain TLP-20 PF06088.11 OAJ18312.1 - 0.33 10.8 2.1 1 9.2 2.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ERCC4 PF02732.15 OAJ18313.1 - 2.2e-21 76.7 0.0 3.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 OAJ18313.1 - 0.027 14.8 0.0 0.08 13.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain UIM PF02809.20 OAJ18313.1 - 0.12 12.3 0.3 0.48 10.4 0.3 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif TPR_11 PF13414.6 OAJ18314.1 - 1e-17 63.5 1.4 0.00026 20.6 0.0 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.28 OAJ18314.1 - 7.9e-17 60.3 1.3 5.3e-05 22.9 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18314.1 - 1.2e-16 59.3 1.9 0.00012 22.0 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18314.1 - 4.6e-14 52.8 1.8 1.7e-08 34.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ18314.1 - 1.3e-11 44.9 0.2 5.5e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18314.1 - 2.2e-11 43.0 1.4 0.009 16.2 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18314.1 - 7.4e-10 38.8 2.8 0.62 11.0 0.0 5.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18314.1 - 4.8e-09 36.4 4.8 0.0084 16.4 1.3 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ18314.1 - 7.7e-09 35.6 0.3 0.00057 20.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ18314.1 - 1.2e-08 34.8 0.7 0.18 12.2 0.0 4.5 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 OAJ18314.1 - 0.00011 21.9 0.7 0.15 11.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 OAJ18314.1 - 0.00051 20.1 0.0 0.067 13.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ18314.1 - 0.0013 18.9 0.3 0.01 16.0 0.0 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ18314.1 - 0.015 15.3 1.5 3.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat T7SS_ESX_EspC PF10824.8 OAJ18314.1 - 0.024 15.1 0.9 0.071 13.6 0.9 1.9 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm TPR_10 PF13374.6 OAJ18314.1 - 0.026 14.4 0.9 15 5.6 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HSCB_C PF07743.13 OAJ18314.1 - 0.26 11.8 4.1 0.23 12.0 1.2 2.1 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain RTC4 PF14474.6 OAJ18315.1 - 2.6e-10 40.5 0.0 6.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Pkinase PF00069.25 OAJ18317.1 - 2.7e-62 210.5 0.0 5.2e-62 209.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18317.1 - 3.6e-31 108.4 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ18317.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ18317.1 - 0.072 13.0 0.1 0.47 10.3 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3402 PF11882.8 OAJ18317.1 - 0.27 10.3 2.3 0.41 9.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Inositol_P PF00459.25 OAJ18319.1 - 2.9e-51 174.6 0.2 9.4e-50 169.6 0.2 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Mg_trans_NIPA PF05653.14 OAJ18339.1 - 6.6e-64 215.8 0.0 3.3e-59 200.4 0.0 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OAJ18339.1 - 0.00025 21.2 0.5 0.00025 21.2 0.5 2.9 3 0 0 3 3 3 1 EamA-like transporter family Ndc1_Nup PF09531.10 OAJ18339.1 - 4.1 6.0 7.2 10 4.7 7.2 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup 7TMR-DISM_7TM PF07695.11 OAJ18339.1 - 8.3 6.2 11.5 0.14 12.1 4.3 1.7 2 0 0 2 2 2 0 7TM diverse intracellular signalling HMG_box PF00505.19 OAJ18340.1 - 4.6e-21 75.0 0.9 4.6e-21 75.0 0.9 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ18340.1 - 7.1e-13 48.9 0.6 7.1e-13 48.9 0.6 1.7 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 OAJ18340.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAJ18340.1 - 0.39 11.3 3.8 0.15 12.7 1.2 1.6 2 0 0 2 2 2 0 YABBY protein DSPc PF00782.20 OAJ18342.1 - 6e-18 64.9 0.0 5.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ18342.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LEAP-2 PF07359.11 OAJ18343.1 - 0.011 15.5 0.3 0.011 15.5 0.3 6.7 7 2 2 9 9 9 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Pex14_N PF04695.13 OAJ18344.1 - 1.2e-28 100.8 0.1 1.2e-28 100.8 0.1 3.5 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NPV_P10 PF05531.12 OAJ18344.1 - 0.00073 20.0 6.1 0.034 14.6 0.7 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 OAJ18344.1 - 0.0012 18.1 0.5 0.002 17.3 0.5 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 OAJ18344.1 - 0.0022 17.5 5.2 0.0033 17.0 5.2 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Laminin_II PF06009.12 OAJ18344.1 - 0.0039 17.2 4.0 0.0039 17.2 4.0 2.1 1 1 0 1 1 1 1 Laminin Domain II DUF885 PF05960.11 OAJ18344.1 - 0.0042 16.8 1.5 0.006 16.3 1.5 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Spc7 PF08317.11 OAJ18344.1 - 0.0046 15.9 10.6 0.0069 15.3 10.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 OAJ18344.1 - 0.0067 16.9 3.9 0.011 16.2 3.9 1.3 1 0 0 1 1 1 1 Fez1 DUF5314 PF17241.2 OAJ18344.1 - 0.0073 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5314) zf-C4H2 PF10146.9 OAJ18344.1 - 0.0079 16.5 0.3 0.0079 16.5 0.3 1.8 2 0 0 2 2 1 1 Zinc finger-containing protein PI3K_P85_iSH2 PF16454.5 OAJ18344.1 - 0.011 15.3 5.0 0.017 14.7 5.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4795 PF16043.5 OAJ18344.1 - 0.013 15.1 5.9 0.021 14.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF948 PF06103.11 OAJ18344.1 - 0.019 15.2 5.1 1.1 9.5 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 OAJ18344.1 - 0.023 14.7 1.2 0.071 13.1 1.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BshC PF10079.9 OAJ18344.1 - 0.027 13.3 3.7 0.036 12.8 3.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4835 PF16119.5 OAJ18344.1 - 0.028 13.6 1.1 0.043 12.9 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Syntaxin PF00804.25 OAJ18344.1 - 0.028 14.1 4.5 0.054 13.2 4.5 1.4 1 0 0 1 1 1 0 Syntaxin RRP36 PF06102.12 OAJ18344.1 - 0.031 14.2 7.5 0.054 13.4 7.5 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 IFT57 PF10498.9 OAJ18344.1 - 0.031 13.2 6.2 0.025 13.6 4.1 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 PilJ PF13675.6 OAJ18344.1 - 0.033 14.2 5.1 0.071 13.1 2.6 2.6 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2968 PF11180.8 OAJ18344.1 - 0.033 13.8 12.1 0.064 12.9 12.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DLP_helical PF18709.1 OAJ18344.1 - 0.039 13.2 4.7 0.057 12.6 4.7 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain DUF3584 PF12128.8 OAJ18344.1 - 0.045 11.3 9.7 0.059 10.9 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 OAJ18344.1 - 0.063 11.2 1.4 0.085 10.8 1.4 1.1 1 0 0 1 1 1 0 Prominin CALCOCO1 PF07888.11 OAJ18344.1 - 0.064 12.1 9.7 0.09 11.6 9.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1759 PF03564.15 OAJ18344.1 - 0.07 13.1 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) FapA PF03961.13 OAJ18344.1 - 0.072 11.7 2.2 0.11 11.1 2.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2431 PF10354.9 OAJ18344.1 - 0.081 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Osmo_CC PF08946.10 OAJ18344.1 - 0.12 12.6 7.3 2.1 8.7 1.9 2.6 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Mt_ATP-synt_D PF05873.12 OAJ18344.1 - 0.13 12.1 4.3 1.1 9.1 4.3 2.0 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4201 PF13870.6 OAJ18344.1 - 0.17 11.6 7.2 0.25 11.0 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_13 PF13166.6 OAJ18344.1 - 0.23 10.1 4.6 0.31 9.6 4.6 1.1 1 0 0 1 1 1 0 AAA domain Allexi_40kDa PF05549.11 OAJ18344.1 - 0.23 10.9 2.4 2.2 7.8 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Lipoprotein_20 PF13942.6 OAJ18344.1 - 0.24 11.3 3.2 0.39 10.6 3.2 1.3 1 0 0 1 1 1 0 YfhG lipoprotein LpxB PF02684.15 OAJ18344.1 - 0.32 9.8 0.9 0.45 9.3 0.9 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase HisKA_3 PF07730.13 OAJ18344.1 - 0.33 11.5 6.0 0.57 10.7 3.6 2.3 1 1 1 2 2 2 0 Histidine kinase EzrA PF06160.12 OAJ18344.1 - 0.4 8.8 8.0 2.7 6.0 8.3 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMPIT PF07851.13 OAJ18344.1 - 0.56 9.4 5.1 0.95 8.6 4.1 1.6 1 1 1 2 2 2 0 TMPIT-like protein Cluap1 PF10234.9 OAJ18344.1 - 0.6 9.5 6.8 1.1 8.6 6.8 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.8 OAJ18344.1 - 0.7 10.0 10.0 0.17 12.0 6.1 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TipAS PF07739.13 OAJ18344.1 - 0.74 10.4 7.2 0.51 10.9 3.3 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain Fib_alpha PF08702.10 OAJ18344.1 - 0.75 10.0 4.4 2.2 8.5 2.7 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CHIP_TPR_N PF18391.1 OAJ18344.1 - 0.91 10.3 6.8 4.7 8.0 6.8 2.1 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain APG6_N PF17675.1 OAJ18344.1 - 0.93 10.0 17.7 0.54 10.8 9.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 OAJ18344.1 - 1.1 9.4 9.1 3.3 7.8 0.7 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.11 OAJ18344.1 - 1.3 9.1 7.4 2.3 8.3 3.6 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HlyD_2 PF12700.7 OAJ18344.1 - 1.4 7.6 3.4 2.4 6.8 3.1 1.4 1 1 0 1 1 1 0 HlyD family secretion protein DUF1664 PF07889.12 OAJ18344.1 - 1.5 8.9 11.9 0.33 11.0 1.1 3.0 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OAJ18344.1 - 1.6 8.8 13.1 32 4.6 13.1 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 OAJ18344.1 - 1.8 8.9 11.2 5.4 7.4 2.9 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 OAJ18344.1 - 1.9 8.9 7.7 1.5 9.2 2.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 OAJ18344.1 - 2.3 8.5 14.3 3.4 8.0 9.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CdvA PF18822.1 OAJ18344.1 - 2.6 7.9 9.8 1.3 8.9 5.3 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Spectrin PF00435.21 OAJ18344.1 - 2.7 8.5 8.6 0.86 10.1 3.2 2.3 1 1 1 2 2 2 0 Spectrin repeat ISG65-75 PF11727.8 OAJ18344.1 - 2.7 7.2 6.6 4.4 6.5 6.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Occludin_ELL PF07303.13 OAJ18344.1 - 2.8 8.7 5.4 16 6.3 5.4 2.0 1 1 0 1 1 1 0 Occludin homology domain FTA4 PF13093.6 OAJ18344.1 - 3.5 7.5 8.9 11 5.8 9.0 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BST2 PF16716.5 OAJ18344.1 - 4 8.1 10.9 6.2 7.5 5.3 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF2203 PF09969.9 OAJ18344.1 - 4.5 8.0 6.7 12 6.7 6.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 OAJ18344.1 - 5.2 7.7 12.5 33 5.2 12.5 2.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 OAJ18344.1 - 6.3 7.3 11.0 5 7.6 1.8 2.4 1 1 1 2 2 2 0 Cell division protein ZapB YabA PF06156.13 OAJ18344.1 - 7.4 7.3 6.3 23 5.7 2.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 OAJ18344.1 - 7.7 7.1 7.3 1.4e+02 3.1 7.3 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 OAJ18344.1 - 9.8 6.2 10.9 28 4.8 11.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus 60KD_IMP PF02096.20 OAJ18345.1 - 2.9e-27 95.6 0.5 3.9e-27 95.2 0.5 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein EURL PF06937.11 OAJ18345.1 - 0.00066 19.2 0.5 0.0011 18.5 0.5 1.2 1 0 0 1 1 1 1 EURL protein ATG_C PF09333.11 OAJ18345.1 - 0.64 10.4 4.2 1.1 9.7 1.9 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain GAT PF03127.14 OAJ18345.1 - 1.3 9.4 2.7 25 5.3 0.1 2.4 2 0 0 2 2 2 0 GAT domain ApoLp-III PF07464.11 OAJ18345.1 - 1.5 8.9 11.2 0.18 11.9 5.4 2.0 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAJ18345.1 - 2.9 8.5 7.0 0.78 10.4 2.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3128 PF11326.8 OAJ18346.1 - 1e-18 67.5 2.2 1.8e-18 66.7 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pkinase PF00069.25 OAJ18347.1 - 4.9e-67 226.1 0.0 1e-66 225.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18347.1 - 2.5e-35 122.0 0.0 6.3e-35 120.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAJ18347.1 - 2e-10 40.3 0.1 3.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OAJ18347.1 - 1.3e-07 31.3 0.1 3.9e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAJ18347.1 - 0.0018 17.3 0.4 0.0034 16.4 0.4 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ18347.1 - 0.03 14.2 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ18347.1 - 0.04 13.5 1.2 0.096 12.3 0.1 2.0 2 0 0 2 2 2 0 RIO1 family PRCH PF03967.13 OAJ18347.1 - 0.43 10.8 7.3 3.2 8.0 0.7 3.9 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region Mus7 PF09462.10 OAJ18348.1 - 4e-101 339.8 0.0 5.7e-101 339.3 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.6 OAJ18348.1 - 0.002 16.6 0.0 0.0037 15.8 0.0 1.3 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal MID_MedPIWI PF18296.1 OAJ18348.1 - 7.2 6.3 8.2 11 5.8 1.0 2.9 2 1 0 2 2 2 0 MID domain of medPIWI UQ_con PF00179.26 OAJ18349.1 - 7.8e-46 155.2 0.0 8.9e-46 155.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ18349.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.26 OAJ18350.1 - 3.2e-31 107.9 0.0 4.9e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HEAT PF02985.22 OAJ18351.1 - 2.7e-23 80.0 7.9 0.00034 20.6 0.0 10.2 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.6 OAJ18351.1 - 8.7e-16 58.1 14.5 1e-09 38.7 0.0 7.7 9 0 0 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 OAJ18351.1 - 4.8e-12 46.1 6.7 0.0013 19.1 0.0 6.2 2 2 4 6 6 6 5 HEAT repeats IBN_N PF03810.19 OAJ18351.1 - 1.1e-10 41.3 1.7 4.3e-07 29.8 0.2 3.7 3 0 0 3 3 3 2 Importin-beta N-terminal domain Arm PF00514.23 OAJ18351.1 - 0.0009 19.2 10.2 0.015 15.3 0.1 5.5 6 1 0 6 6 6 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 OAJ18351.1 - 0.001 19.6 0.3 1.2 9.8 0.1 4.6 4 1 2 6 6 5 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 OAJ18351.1 - 0.001 18.2 2.4 0.0053 15.9 1.4 2.6 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 OAJ18351.1 - 0.0013 18.5 1.0 3.4 7.4 0.0 3.6 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Xpo1 PF08389.12 OAJ18351.1 - 0.0089 16.1 1.2 1.6 8.7 0.0 3.3 2 1 1 3 3 3 1 Exportin 1-like protein Cnd3 PF12719.7 OAJ18351.1 - 0.045 13.0 1.4 2 7.5 0.7 3.4 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 OAJ18351.1 - 0.22 11.4 0.9 23 4.8 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) OTU PF02338.19 OAJ18352.1 - 4.8e-13 49.7 0.0 8.1e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAJ18352.1 - 0.0024 17.3 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Gp_dh_C PF02800.20 OAJ18353.1 - 4e-69 231.2 0.0 5.4e-69 230.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAJ18353.1 - 5e-27 94.2 0.0 1.1e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RINGv PF12906.7 OAJ18354.1 - 5.8e-06 26.3 8.1 1.6e-05 24.9 2.7 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_4 PF14570.6 OAJ18354.1 - 0.066 13.0 2.3 0.14 12.0 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAJ18354.1 - 0.11 12.1 1.4 0.26 10.9 1.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAJ18354.1 - 0.2 11.8 1.5 0.48 10.6 1.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 OAJ18354.1 - 0.8 10.1 9.3 0.083 13.2 4.3 1.8 2 0 0 2 2 2 0 Ring finger domain VHS PF00790.19 OAJ18355.1 - 3.4e-20 72.3 0.2 5.2e-20 71.7 0.2 1.3 1 0 0 1 1 1 1 VHS domain Vps35 PF03635.17 OAJ18356.1 - 0 1023.3 0.0 0 1022.7 0.0 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.22 OAJ18356.1 - 2.2e-20 72.2 0.0 4.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ18356.1 - 0.0062 16.1 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_12 PF13087.6 OAJ18357.1 - 2.7e-46 157.7 0.0 4.8e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ18357.1 - 1.2e-39 136.7 0.0 7.7e-39 134.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ18357.1 - 5.1e-14 52.8 0.1 4.4e-13 49.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ18357.1 - 3.5e-10 39.9 2.4 6.3e-08 32.6 1.0 2.9 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 OAJ18357.1 - 0.00043 19.9 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OAJ18357.1 - 0.00062 19.6 0.3 4.6 6.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAJ18357.1 - 0.019 14.4 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.14 OAJ18357.1 - 0.023 14.7 0.1 0.97 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 OAJ18357.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 OAJ18357.1 - 0.043 14.2 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain Hist_deacetyl PF00850.19 OAJ18371.1 - 1.5e-83 280.8 0.0 2.1e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ATP-synt_F PF01990.17 OAJ18372.1 - 2.2e-28 98.4 0.0 2.5e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF5427 PF10310.9 OAJ18373.1 - 1.6e-37 129.6 1.5 2.4e-36 125.7 0.4 2.8 2 1 0 2 2 2 1 Family of unknown function (DUF5427) MSA-2c PF12238.8 OAJ18373.1 - 4.8 7.1 21.1 0.15 12.1 3.8 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c CBS PF00571.28 OAJ18375.1 - 1.6e-28 98.9 8.5 5.1e-07 30.1 0.3 5.1 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 OAJ18375.1 - 1.3e-06 28.2 0.0 1.2e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 PB1 domain GP40 PF11025.8 OAJ18375.1 - 0.024 14.4 0.3 0.024 14.4 0.3 2.5 2 1 1 3 3 3 0 Glycoprotein GP40 of Cryptosporidium NYN PF01936.18 OAJ18375.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 NYN domain Spt5_N PF11942.8 OAJ18375.1 - 5.4 8.1 10.2 33 5.5 7.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_88 PF07470.13 OAJ18376.1 - 1.5e-16 60.4 0.2 3.4e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 WXG100 PF06013.12 OAJ18376.1 - 0.13 12.5 0.2 0.37 11.0 0.2 1.8 1 0 0 1 1 1 0 Proteins of 100 residues with WXG EphA2_TM PF14575.6 OAJ18376.1 - 0.24 12.3 0.2 0.63 10.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 5TM-5TMR_LYT PF07694.12 OAJ18376.1 - 0.32 10.5 1.8 0.6 9.6 1.8 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ATP12 PF07542.11 OAJ18377.1 - 5.5e-38 130.0 0.0 7.9e-38 129.4 0.0 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein PspC PF04024.12 OAJ18377.1 - 0.2 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 PspC domain SANT_DAMP1_like PF16282.5 OAJ18378.1 - 1.2e-29 102.3 4.6 1.9e-29 101.7 4.6 1.3 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Complex1_LYR PF05347.15 OAJ18379.1 - 2.2e-10 40.4 4.8 3.6e-10 39.7 4.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ18379.1 - 3.2e-05 24.6 0.3 4.4e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like FHA PF00498.26 OAJ18380.1 - 5e-14 52.4 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 OAJ18380.1 - 5.1e-11 42.1 12.4 8.3e-11 41.4 12.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAJ18380.1 - 2.8e-07 30.8 13.7 4.2e-07 30.2 13.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ18380.1 - 0.0021 17.9 14.3 0.0034 17.2 14.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ18380.1 - 0.0035 17.6 9.7 0.0068 16.7 9.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ18380.1 - 0.007 16.4 5.6 0.012 15.7 5.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ18380.1 - 0.013 15.3 13.2 0.021 14.7 13.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ18380.1 - 0.09 12.8 12.3 0.15 12.0 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 OAJ18380.1 - 1.1 8.9 9.0 1.9 8.2 9.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ18380.1 - 1.4 9.0 12.9 2.6 8.2 12.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 OAJ18380.1 - 1.8 8.5 8.8 3.3 7.7 8.8 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 OAJ18380.1 - 5.9 6.8 11.9 11 6.0 11.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_6 PF12774.7 OAJ18381.1 - 6.2e-130 432.9 0.0 3.1e-129 430.6 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OAJ18381.1 - 5.3e-116 388.0 4.2 5.3e-116 388.0 4.2 3.6 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OAJ18381.1 - 4.1e-109 365.8 22.1 4.6e-109 365.6 13.4 2.9 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 OAJ18381.1 - 1.9e-42 144.8 0.0 3.5e-36 124.4 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 OAJ18381.1 - 2e-40 138.8 0.0 6.9e-40 137.0 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 OAJ18381.1 - 1.2e-27 96.6 0.0 4.3e-13 49.4 0.0 6.0 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OAJ18381.1 - 6.4e-15 55.4 0.0 2.1e-14 53.7 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OAJ18381.1 - 2.9e-14 53.5 0.1 0.0055 17.0 0.0 5.8 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 OAJ18381.1 - 1.7e-13 51.1 0.0 0.0068 16.8 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ18381.1 - 2e-10 41.3 0.6 0.073 13.5 0.2 6.7 5 1 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.6 OAJ18381.1 - 1.4e-09 38.2 0.0 0.12 12.6 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAJ18381.1 - 1.7e-07 31.8 0.0 1.5 9.4 0.0 5.0 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 OAJ18381.1 - 4.9e-07 29.1 0.0 0.0051 15.9 0.0 3.5 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.6 OAJ18381.1 - 4.8e-06 27.0 2.8 0.28 11.5 0.0 5.5 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.6 OAJ18381.1 - 1.8e-05 24.5 0.9 4.3 7.0 0.0 4.8 4 1 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OAJ18381.1 - 3.9e-05 23.1 2.9 0.59 9.5 0.0 4.1 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ18381.1 - 0.00022 21.0 0.7 0.71 9.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_lid_1 PF17857.1 OAJ18381.1 - 0.00069 19.8 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 OAJ18381.1 - 0.0033 17.1 0.1 9.2 6.1 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ18381.1 - 0.0037 17.2 0.1 23 4.8 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain ABC_tran PF00005.27 OAJ18381.1 - 0.0042 17.6 0.2 62 4.1 0.0 4.7 4 0 0 4 4 3 0 ABC transporter AAA_24 PF13479.6 OAJ18381.1 - 0.0061 16.3 1.0 20 4.8 0.0 5.1 5 0 0 5 5 5 0 AAA domain AAA_11 PF13086.6 OAJ18381.1 - 0.011 15.6 0.7 1.2 8.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 OAJ18381.1 - 0.014 15.0 0.0 0.54 9.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAJ18381.1 - 0.017 15.5 0.1 18 5.7 0.0 4.4 4 0 0 4 4 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 OAJ18381.1 - 0.018 14.4 0.0 18 4.6 0.0 3.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family RuvB_N PF05496.12 OAJ18381.1 - 0.06 13.1 0.1 4.6 7.0 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain HNH_4 PF13395.6 OAJ18381.1 - 0.12 12.3 0.0 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 HNH endonuclease DUF3087 PF11286.8 OAJ18381.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) NPV_P10 PF05531.12 OAJ18381.1 - 2.8 8.5 11.0 2.5 8.6 0.0 5.7 6 1 0 6 6 4 0 Nucleopolyhedrovirus P10 protein zf-rbx1 PF12678.7 OAJ18382.1 - 2e-25 88.8 12.4 3.2e-25 88.2 12.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ18382.1 - 1.5e-17 63.4 11.9 2e-17 63.0 11.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAJ18382.1 - 1e-06 29.0 16.6 9.3e-05 22.7 16.6 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ18382.1 - 1.5e-05 24.7 3.0 1.5e-05 24.7 3.0 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ18382.1 - 0.00037 20.3 10.8 0.0041 17.0 10.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ18382.1 - 0.01 15.7 10.0 0.1 12.5 3.6 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cathelicidins PF00666.17 OAJ18382.1 - 0.071 13.4 0.4 0.13 12.6 0.4 1.6 1 1 0 1 1 1 0 Cathelicidin Zn_ribbon_17 PF17120.5 OAJ18382.1 - 0.18 11.5 14.6 0.064 12.9 4.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAJ18382.1 - 2.8 8.2 16.3 0.19 11.9 9.2 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 OAJ18382.1 - 3.2 7.9 11.8 0.83 9.7 7.7 2.2 2 1 0 2 2 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 OAJ18382.1 - 3.5 7.5 20.5 52 3.7 17.3 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 OAJ18382.1 - 5.2 7.1 12.2 27 4.8 12.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain adh_short PF00106.25 OAJ18384.1 - 1.3e-05 24.7 0.0 0.064 12.7 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase MFS_1 PF07690.16 OAJ18385.1 - 1.8e-17 63.3 45.8 2e-17 63.2 38.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Amidohydro_1 PF01979.20 OAJ18386.1 - 6.9e-06 25.6 0.1 4.2e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 OAJ18386.1 - 6.9e-05 22.8 0.1 0.00015 21.7 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase bZIP_1 PF00170.21 OAJ18387.1 - 3.7e-05 23.7 9.7 0.00013 22.0 9.7 1.9 1 0 0 1 1 1 1 bZIP transcription factor Kinesin_assoc PF16183.5 OAJ18387.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 3.5 3 1 0 3 3 3 1 Kinesin-associated Ino80_Iec3 PF14612.6 OAJ18387.1 - 0.015 16.0 0.5 0.015 16.0 0.5 2.8 2 1 1 3 3 3 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF1749 PF08538.10 OAJ18388.1 - 0.0062 15.7 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 OAJ18388.1 - 0.012 16.3 1.2 0.012 16.3 1.2 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ18388.1 - 0.039 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 OAJ18388.1 - 0.088 12.1 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Sec1 PF00995.23 OAJ18389.1 - 5.4e-114 382.5 0.0 8.4e-114 381.9 0.0 1.3 1 1 0 1 1 1 1 Sec1 family ubiquitin PF00240.23 OAJ18390.1 - 2.4e-167 543.0 29.0 5.8e-33 112.5 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 OAJ18390.1 - 8e-78 256.3 30.2 4.4e-15 55.3 0.8 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ18390.1 - 1.8e-27 95.6 16.0 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ18390.1 - 3.2e-19 68.6 7.4 0.041 13.8 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ18390.1 - 4.9e-17 62.0 5.6 0.18 11.9 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 OAJ18390.1 - 6.5e-17 61.7 12.9 0.066 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 OAJ18390.1 - 3.6e-16 59.6 3.5 0.37 11.4 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ18390.1 - 9.7e-12 45.0 1.8 1.5 8.6 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 OAJ18390.1 - 1.3e-08 34.4 1.8 1.9 7.7 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 OAJ18390.1 - 2.1e-07 31.2 0.0 40 4.7 0.0 5.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 OAJ18390.1 - 2.4e-07 30.7 33.2 23 5.1 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF3861 PF12977.7 OAJ18390.1 - 3.2e-07 30.4 5.6 16 5.8 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 OAJ18390.1 - 5.6e-07 30.2 1.3 48 4.8 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain Big_3_3 PF13750.6 OAJ18390.1 - 8.3e-06 25.5 0.2 43 3.7 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 OAJ18390.1 - 1.3e-05 24.7 0.1 27 4.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 OAJ18390.1 - 2.4e-05 24.4 8.5 9.2 6.4 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase NEAT PF05031.12 OAJ18390.1 - 4.9e-05 23.9 5.9 0.98 10.1 0.3 3.5 1 1 3 4 4 4 4 Iron Transport-associated domain ACT_5 PF13710.6 OAJ18390.1 - 5.8e-05 22.8 8.2 26 4.8 0.0 5.3 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 OAJ18390.1 - 0.00024 21.6 0.2 1.7e+02 2.9 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 OAJ18390.1 - 0.00046 20.3 0.0 1.2e+02 2.9 0.0 5.5 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 OAJ18390.1 - 0.0008 19.9 2.6 1.6e+02 3.0 0.0 5.1 5 0 0 5 5 5 0 ACT domain YcgR_2 PF12945.7 OAJ18390.1 - 0.0051 16.9 10.0 61 3.9 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR Phage-tail_1 PF09097.10 OAJ18390.1 - 0.039 13.7 2.1 1.8e+02 1.8 0.0 4.6 5 0 0 5 5 5 0 Baseplate structural protein, domain 1 Tash_PEST PF07708.11 OAJ18390.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif ProRS-C_2 PF09181.10 OAJ18390.1 - 0.2 11.8 9.2 1.5e+02 2.6 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 OAJ18390.1 - 0.24 11.2 9.4 1.4e+02 2.4 0.0 6.2 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain FlgD_ig PF13860.6 OAJ18390.1 - 2.6 8.0 13.8 1.2e+02 2.6 0.1 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 OAJ18390.1 - 3.1 8.3 14.3 1.8e+04 -6.9 14.3 4.9 1 1 0 1 1 0 0 Phage tail sheath protein beta-sandwich domain eIF_4EBP PF05456.11 OAJ18391.1 - 1.6e-11 44.2 1.7 4.3e-11 42.8 1.7 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ubiquitin PF00240.23 OAJ18392.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ18392.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ18392.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ18392.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ18392.1 - 9.1e-12 45.2 2.6 0.028 14.8 0.1 3.1 1 1 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ18392.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ18392.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ18392.1 - 1.5e-07 31.4 0.3 0.61 9.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAJ18392.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAJ18392.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAJ18392.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAJ18392.1 - 0.00032 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAJ18392.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 OAJ18392.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 OAJ18392.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 OAJ18392.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 OAJ18392.1 - 0.0045 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 OAJ18392.1 - 0.0087 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 OAJ18392.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 OAJ18392.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 OAJ18392.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAJ18392.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 OAJ18392.1 - 0.06 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 OAJ18392.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 OAJ18392.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 OAJ18392.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAJ18392.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 OAJ18392.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 OAJ18392.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 OAJ18392.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAJ18392.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Epimerase PF01370.21 OAJ18405.1 - 0.00014 21.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAJ18405.1 - 0.0015 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OAJ18405.1 - 0.0095 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ18405.1 - 0.19 11.1 0.1 5.6 6.3 0.0 2.6 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase ECH_1 PF00378.20 OAJ18407.1 - 8.1e-20 71.2 0.0 1.8e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ18407.1 - 1.3e-06 28.2 0.0 3.1e-06 26.9 0.0 1.6 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Rhodanese PF00581.20 OAJ18409.1 - 1.1e-06 29.1 0.0 1.6e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Glutaredoxin PF00462.24 OAJ18410.1 - 1.1e-18 67.2 0.0 1.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 OAJ18410.1 - 0.00023 21.6 0.0 0.00045 20.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 OAJ18410.1 - 0.00044 20.6 0.0 0.00053 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 OAJ18410.1 - 0.0032 17.3 0.0 0.1 12.3 0.0 2.0 1 1 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 OAJ18410.1 - 0.0038 17.4 0.3 3.5 7.8 0.3 2.1 1 1 0 2 2 2 2 Thioredoxin GST_N_3 PF13417.6 OAJ18410.1 - 0.0054 17.1 0.0 0.0073 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 OAJ18410.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin domain GST_N_2 PF13409.6 OAJ18410.1 - 0.03 14.6 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain S6OS1 PF15676.5 OAJ18411.1 - 0.14 10.7 0.2 0.21 10.0 0.2 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family FAM70 PF14967.6 OAJ18411.1 - 0.82 9.1 2.6 0.79 9.1 0.9 1.8 1 1 0 1 1 1 0 FAM70 protein WD40 PF00400.32 OAJ18412.1 - 1.6e-25 88.8 0.3 3.5e-06 27.7 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18412.1 - 2.1e-10 40.7 0.1 0.00036 20.8 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ18412.1 - 0.0012 17.6 1.1 0.0016 17.2 0.2 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 OAJ18412.1 - 0.041 13.2 0.0 1.1 8.6 0.0 2.8 3 1 0 3 3 3 0 WD40-like domain Gmad1 PF10647.9 OAJ18412.1 - 0.053 13.3 1.5 0.51 10.1 0.3 2.2 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 OAJ18412.1 - 0.21 10.6 0.3 3.4 6.6 0.1 2.6 2 1 1 3 3 3 0 Coatomer WD associated region Myb_DNA-binding PF00249.31 OAJ18413.1 - 3.1e-34 116.9 6.4 2.6e-13 49.9 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ18413.1 - 7.9e-26 90.1 0.2 5.6e-11 42.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ18413.1 - 0.046 13.6 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Myb DNA-binding like Rap1_C PF11626.8 OAJ18413.1 - 0.056 13.5 3.7 4.9 7.3 0.1 3.2 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 OAJ18413.1 - 0.44 11.0 1.9 44 4.5 0.0 3.2 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Caudo_TAP PF02413.17 OAJ18415.1 - 0.11 12.6 3.3 0.15 12.2 3.3 1.1 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK DUF3439 PF11921.8 OAJ18415.1 - 1.8 8.5 9.9 3 7.8 9.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TFIIA PF03153.13 OAJ18415.1 - 1.8 8.4 20.3 2.1 8.2 20.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 OAJ18415.1 - 2.5 7.6 9.0 3.1 7.3 9.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Dicty_REP PF05086.12 OAJ18415.1 - 3.7 5.4 11.7 4.3 5.2 11.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.10 OAJ18415.1 - 8.6 4.9 17.5 11 4.6 17.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_cc PF11790.8 OAJ18416.1 - 3.2e-39 134.9 0.0 4.4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Zip PF02535.22 OAJ18416.1 - 0.00015 21.1 5.6 0.00015 21.1 5.6 2.1 2 0 0 2 2 2 1 ZIP Zinc transporter Pro-rich PF15240.6 OAJ18416.1 - 0.018 15.3 1.8 0.018 15.3 1.8 1.7 2 0 0 2 2 2 0 Proline-rich Neur_chan_memb PF02932.16 OAJ18416.1 - 0.16 12.0 2.0 0.4 10.7 2.0 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OAJ18416.1 - 1.7 7.3 8.0 0.076 11.8 0.8 1.9 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 OAJ18416.1 - 8.7 7.4 7.2 2.3 9.2 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Promethin PF16015.5 OAJ18417.1 - 0.062 13.2 4.0 2.1 8.3 0.1 3.5 3 0 0 3 3 3 0 Promethin DPBB_1 PF03330.18 OAJ18419.1 - 1.1e-09 38.5 0.1 1.8e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Bd3614-deam PF14439.6 OAJ18420.1 - 0.036 14.1 0.3 0.087 12.9 0.3 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase Terpene_synth PF01397.21 OAJ18420.1 - 0.067 12.9 0.1 0.57 9.8 0.0 2.3 1 1 1 2 2 2 0 Terpene synthase, N-terminal domain Metallophos_2 PF12850.7 OAJ18422.1 - 8.7e-18 65.1 0.1 1.5e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OAJ18422.1 - 0.00091 19.8 0.8 0.13 12.7 0.2 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase SUZ PF12752.7 OAJ18423.1 - 2.1e-12 47.6 1.4 2.1e-12 47.6 1.4 2.8 2 1 0 2 2 2 1 SUZ domain Acetyltransf_1 PF00583.25 OAJ18424.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MRPL52 PF18699.1 OAJ18426.1 - 0.6 10.3 3.0 1.4 9.1 3.0 1.6 1 0 0 1 1 1 0 Mitoribosomal protein mL52 NOA36 PF06524.12 OAJ18426.1 - 0.61 9.4 1.9 1.1 8.5 1.9 1.3 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 OAJ18426.1 - 1.7 9.7 12.2 5.6 8.0 12.2 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PLA2_B PF01735.18 OAJ18427.1 - 6.4e-11 41.3 0.0 1.9e-05 23.3 1.1 2.4 2 0 0 2 2 2 2 Lysophospholipase catalytic domain HhH-GPD PF00730.25 OAJ18428.1 - 1.4e-09 38.4 0.0 2.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ18428.1 - 0.039 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 OAJ18428.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.8 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ndc1_Nup PF09531.10 OAJ18428.1 - 1.1 7.9 2.4 1.7 7.2 2.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_16 PF10294.9 OAJ18429.1 - 2.2e-07 30.8 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 OAJ18429.1 - 0.011 16.5 0.0 0.21 12.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ18429.1 - 0.012 15.4 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ18429.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.31 OAJ18431.1 - 0.00015 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OAJ18431.1 - 0.00019 21.5 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 Apt1 PF10351.9 OAJ18445.1 - 2 7.2 3.9 2.3 7.0 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Wzz PF02706.15 OAJ18446.1 - 0.11 12.8 0.2 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Chain length determinant protein FAM176 PF14851.6 OAJ18446.1 - 0.47 10.1 2.1 11 5.6 0.9 2.3 2 0 0 2 2 2 0 FAM176 family TFIIE-A_C PF11521.8 OAJ18446.1 - 4.3 7.7 10.1 15 6.0 1.0 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Peptidase_M16_M PF16187.5 OAJ18447.1 - 8.3e-88 294.3 0.0 1.9e-87 293.1 0.0 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OAJ18447.1 - 2.9e-41 140.9 0.3 1.6e-40 138.5 0.0 2.5 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ18447.1 - 1.9e-37 129.1 0.1 2.7e-21 76.4 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain DUF4265 PF14085.6 OAJ18447.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) MbeB_N PF04837.12 OAJ18447.1 - 8.4 6.8 6.6 0.39 11.1 0.4 2.0 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Exo_endo_phos PF03372.23 OAJ18448.1 - 2.1e-21 76.5 0.1 2.1e-21 76.5 0.1 3.2 3 2 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 OAJ18448.1 - 1e-12 47.6 15.9 4.8e-07 29.4 1.7 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAJ18448.1 - 5.2e-10 39.4 2.1 0.00069 20.0 0.1 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) CENP-B_dimeris PF09026.10 OAJ18448.1 - 0.001 19.4 6.5 0.0026 18.1 6.5 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Pam16 PF03656.13 OAJ18449.1 - 2.6e-13 50.1 5.3 3.9e-06 26.9 1.8 3.2 1 1 0 2 2 2 2 Pam16 SR-25 PF10500.9 OAJ18449.1 - 8.2 6.0 11.9 4.1 7.0 6.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 OAJ18450.1 - 1.8e-39 135.7 0.0 7.8e-24 84.5 0.0 3.7 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18450.1 - 2.3e-15 56.6 0.0 9.8e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAJ18450.1 - 0.03 14.3 0.5 0.42 10.5 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Nop14 PF04147.12 OAJ18450.1 - 6.3 4.9 13.9 11 4.1 13.9 1.3 1 0 0 1 1 1 0 Nop14-like family Steroid_dh PF02544.16 OAJ18451.1 - 1e-21 77.5 1.5 1.8e-07 31.3 0.4 3.8 4 0 0 4 4 4 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAJ18451.1 - 0.0045 16.5 0.5 0.019 14.5 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) AICARFT_IMPCHas PF01808.18 OAJ18452.1 - 2.1e-84 283.5 0.1 2.9e-84 283.0 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAJ18452.1 - 2.4e-21 75.7 0.0 4.5e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain CBM_25 PF03423.13 OAJ18452.1 - 0.084 13.1 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) SET PF00856.28 OAJ18453.1 - 0.0077 16.6 0.0 0.085 13.2 0.0 2.4 1 1 1 2 2 2 1 SET domain HATPase_c PF02518.26 OAJ18454.1 - 9.2e-29 100.2 0.1 2.1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ18454.1 - 8.7e-25 87.1 0.0 5.2e-24 84.6 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ18454.1 - 4.2e-20 71.6 0.1 1.4e-19 69.9 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 OAJ18454.1 - 1.1e-17 64.3 0.8 3.1e-07 30.6 0.0 5.2 5 0 0 5 5 5 4 PAS fold PAS_3 PF08447.12 OAJ18454.1 - 1.3e-17 63.8 1.1 3.3e-17 62.6 0.4 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OAJ18454.1 - 1.1e-11 44.7 0.0 0.014 15.4 0.0 5.1 5 0 0 5 5 5 3 PAS fold PAS_9 PF13426.7 OAJ18454.1 - 1.5e-08 34.8 0.0 1.6e-06 28.3 0.0 3.9 4 1 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.6 OAJ18454.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 OAJ18454.1 - 0.011 15.7 0.0 14 5.8 0.0 4.1 4 0 0 4 4 4 0 PAS domain AAA_31 PF13614.6 OAJ18454.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.6 OAJ18455.1 - 7.6e-56 188.9 14.8 9.5e-56 188.6 14.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like HATPase_c PF02518.26 OAJ18456.1 - 3.6e-30 104.7 0.0 4.4e-29 101.2 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ18456.1 - 3.6e-24 85.1 0.2 8.3e-24 83.9 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAJ18456.1 - 2.5e-23 82.4 6.9 9.8e-13 48.3 0.2 6.5 5 1 0 5 5 5 3 PAS fold HisKA PF00512.25 OAJ18456.1 - 1.4e-19 69.9 0.1 3.9e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAJ18456.1 - 1e-13 51.4 0.7 1e-13 51.4 0.7 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OAJ18456.1 - 6.8e-13 48.6 0.5 0.0026 17.7 0.0 5.4 6 0 0 6 6 6 3 PAS fold PAS_9 PF13426.7 OAJ18456.1 - 1e-09 38.6 0.0 2.8e-07 30.7 0.0 3.8 4 1 0 4 4 4 1 PAS domain PAS_8 PF13188.7 OAJ18456.1 - 0.00027 20.9 0.0 40 4.4 0.0 4.5 4 0 0 4 4 4 0 PAS domain HATPase_c_3 PF13589.6 OAJ18456.1 - 0.0087 15.9 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCM2_N PF12619.8 OAJ18456.1 - 0.027 14.8 0.2 0.06 13.6 0.2 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 AMP-binding PF00501.28 OAJ18457.1 - 4.8e-211 700.8 0.0 1.5e-73 247.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 OAJ18457.1 - 4.5e-121 404.7 0.0 2.8e-33 115.3 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 OAJ18457.1 - 8.3e-37 125.4 2.4 3.6e-08 33.6 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ18457.1 - 1.7e-05 25.7 0.2 2.5 9.2 0.0 4.7 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 OAJ18457.1 - 0.00084 19.2 0.2 10 5.8 0.0 4.4 4 0 0 4 4 4 1 Wax ester synthase-like Acyl-CoA acyltransferase domain P16-Arc PF04699.14 OAJ18458.1 - 6.9e-51 172.6 0.0 7.7e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UTP25 PF06862.12 OAJ18459.1 - 1.5e-142 475.7 0.0 2.1e-142 475.3 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Paz_1 PF18349.1 OAJ18459.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 PAZ domain TPR_2 PF07719.17 OAJ18460.1 - 1e-08 34.6 2.1 0.082 13.1 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ18460.1 - 2.8e-08 33.4 8.4 0.062 13.2 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18460.1 - 1.6e-06 28.3 14.4 0.034 14.5 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18460.1 - 0.009 16.2 0.0 0.24 11.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18460.1 - 0.012 16.3 18.3 1.1 10.3 0.0 8.2 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ18460.1 - 0.016 15.7 9.6 0.58 10.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18460.1 - 0.033 14.8 10.2 6.1 7.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ18460.1 - 0.052 13.6 0.8 1.6 9.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18460.1 - 0.082 12.8 0.7 4.2 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.18 OAJ18461.1 - 1.4e-33 116.3 31.3 1.6e-33 116.0 31.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FUSC_2 PF13515.6 OAJ18473.1 - 3.8e-24 85.2 7.5 3.8e-24 85.2 7.5 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAJ18473.1 - 1.4e-11 44.0 5.3 2.2e-09 36.7 1.2 2.6 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 OAJ18473.1 - 3e-10 39.3 1.2 3e-10 39.3 1.2 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 OAJ18473.1 - 2.1e-08 34.3 0.2 1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 OAJ18473.1 - 0.0062 15.6 3.4 1.2 8.1 2.2 2.4 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS DUF21 PF01595.20 OAJ18473.1 - 0.36 10.5 2.2 1.3 8.7 2.2 1.9 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain ArAE_1 PF06081.11 OAJ18473.1 - 6.4 6.9 13.3 0.029 14.5 2.9 2.5 2 2 0 2 2 2 0 Aromatic acid exporter family member 1 Linker_histone PF00538.19 OAJ18474.1 - 4.6e-21 75.0 0.3 7.8e-21 74.2 0.3 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family AHH PF14412.6 OAJ18474.1 - 0.031 14.3 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Bromodomain PF00439.25 OAJ18475.1 - 8.4e-26 89.9 0.2 1.7e-25 88.9 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OAJ18475.1 - 1.2e-07 31.9 0.1 3.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ18475.1 - 6.3e-06 26.1 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ18475.1 - 0.00035 20.9 0.1 0.00067 20.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltrn_RNA_3 PF02598.17 OAJ18476.1 - 3.7e-98 328.6 0.0 4.5e-98 328.3 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SPATA3 PF15662.5 OAJ18476.1 - 0.51 11.0 5.1 1.1 9.8 5.1 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DUF4611 PF15387.6 OAJ18476.1 - 1 9.6 7.2 3.6 7.9 7.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Trypan_PARP PF05887.11 OAJ18476.1 - 1.3 9.0 15.0 0.14 12.2 10.4 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.6 OAJ18476.1 - 1.7 9.1 5.8 4.5 7.7 5.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.18 OAJ18477.1 - 1.6e-05 24.9 3.9 4.8e-05 23.4 3.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSC PF09402.10 OAJ18478.1 - 3.8e-22 79.2 0.0 2.5e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain NGP1NT PF08153.12 OAJ18479.1 - 1.8e-46 157.5 0.0 1.8e-46 157.5 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAJ18479.1 - 5e-16 58.8 0.0 2.7e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ18479.1 - 0.00033 20.2 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 OAJ18479.1 - 0.00038 19.9 0.1 0.045 13.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ18479.1 - 0.001 19.0 0.0 0.0029 17.5 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 OAJ18479.1 - 0.82 9.7 0.0 0.82 9.7 0.0 4.1 4 1 1 5 5 5 0 Dynamin family Cwf_Cwc_15 PF04889.12 OAJ18479.1 - 7.1 6.3 38.6 4.9 6.8 16.3 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DCP1 PF06058.13 OAJ18480.1 - 8.3e-24 83.8 0.0 1.3e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Mlh1_C PF16413.5 OAJ18481.1 - 1.5e-68 231.1 0.0 3.5e-68 229.9 0.0 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAJ18481.1 - 7.4e-31 106.3 0.0 1.5e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ18481.1 - 3.1e-12 46.5 0.0 1.5e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ18481.1 - 4.3e-08 33.7 0.0 4.8e-07 30.3 0.0 2.3 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RRP7 PF12923.7 OAJ18482.1 - 0.021 14.9 1.2 0.047 13.8 1.2 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain ICMT PF04140.14 OAJ18483.1 - 8.6e-27 93.4 0.0 1.7e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ18483.1 - 4.9e-11 43.0 1.0 4.9e-11 43.0 1.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAJ18483.1 - 0.00015 21.3 0.1 0.00021 20.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 OAJ18483.1 - 0.0077 15.8 0.2 0.0077 15.8 0.2 1.9 2 0 0 2 2 2 1 NnrU protein ERG4_ERG24 PF01222.17 OAJ18483.1 - 0.022 13.5 0.4 0.036 12.8 0.2 1.4 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Lyase_8 PF02278.18 OAJ18484.1 - 0.11 11.9 0.1 7.9 5.9 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide lyase family 8, super-sandwich domain QueF_N PF14819.6 OAJ18485.1 - 4e-08 33.6 0.9 0.66 10.3 0.0 4.4 2 1 1 4 4 4 4 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term LepB_GAP_C PF18227.1 OAJ18485.1 - 8.1e-07 29.5 0.0 0.8 10.3 0.0 4.2 1 1 4 5 5 5 4 LepB GAP domain C-terminal subdomain Raf1_N PF18578.1 OAJ18485.1 - 0.011 16.2 12.5 69 4.0 0.0 6.9 1 1 7 8 8 8 0 Rubisco accumulation factor 1 alpha helical domain DUF4894 PF16235.5 OAJ18485.1 - 0.019 15.3 1.4 4.8 7.6 0.1 3.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4894) CAP_GLY PF01302.25 OAJ18485.1 - 0.038 14.0 0.1 0.23 11.5 0.0 1.9 1 1 0 2 2 2 0 CAP-Gly domain Na_H_Exchanger PF00999.21 OAJ18486.1 - 3.1e-56 190.8 11.7 4e-56 190.4 11.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAJ18486.1 - 0.0078 16.3 3.1 0.042 13.9 0.0 3.0 3 0 0 3 3 3 1 YrhC-like protein 7tm_3 PF00003.22 OAJ18486.1 - 2.1 8.0 7.9 0.41 10.4 2.6 2.2 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DHquinase_I PF01487.15 OAJ18487.1 - 5.4e-35 121.7 0.0 2.6e-34 119.5 0.0 2.0 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OAJ18487.1 - 1.1e-22 80.9 0.0 1.8e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAJ18487.1 - 0.078 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ18487.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 OAJ18488.1 - 9.2e-17 60.8 0.0 2.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ18488.1 - 4.1e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GFO_IDH_MocA PF01408.22 OAJ18489.1 - 1.9e-16 60.9 0.0 3.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ18489.1 - 1.1e-11 44.7 0.0 2.4e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CRAL_TRIO_2 PF13716.6 OAJ18490.1 - 1.2e-29 103.2 0.0 2.1e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 OAJ18490.1 - 3.2e-25 88.7 0.0 5.3e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.27 OAJ18491.1 - 2.6e-54 181.1 0.6 8.3e-21 73.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Clat_adaptor_s PF01217.20 OAJ18492.1 - 5.7e-53 178.7 1.9 6.7e-53 178.4 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PIN_4 PF13638.6 OAJ18493.1 - 1.1e-05 25.8 0.0 4.2e-05 23.9 0.0 2.1 2 1 0 2 2 2 1 PIN domain Mif2_N PF15624.6 OAJ18493.1 - 0.11 13.2 0.3 0.11 13.2 0.3 2.4 3 0 0 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal FAD_binding_7 PF03441.14 OAJ18495.1 - 1.6e-50 171.4 0.3 2.4e-50 170.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ18495.1 - 5.3e-20 72.1 0.0 1.3e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 DNA photolyase 7TMR-DISMED2 PF07696.11 OAJ18495.1 - 0.069 13.2 0.3 0.36 10.9 0.1 2.1 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 EMP70 PF02990.16 OAJ18496.1 - 2.6e-181 603.8 0.7 3.3e-181 603.5 0.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Guanylate_kin PF00625.21 OAJ18497.1 - 7e-56 188.8 0.0 8.5e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OAJ18497.1 - 2.5e-07 31.2 0.2 5.9e-07 30.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ18497.1 - 5.4e-07 30.0 0.0 1.4e-06 28.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ18497.1 - 5.4e-05 23.2 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 OAJ18497.1 - 9.1e-05 22.7 0.0 0.00028 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ18497.1 - 9.2e-05 23.0 0.0 0.00028 21.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 OAJ18497.1 - 0.0001 22.8 0.0 0.00012 22.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 OAJ18497.1 - 0.00042 20.4 0.0 0.00075 19.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 OAJ18497.1 - 0.001 18.8 0.0 0.017 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ18497.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 OAJ18497.1 - 0.0059 16.6 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OAJ18497.1 - 0.0075 16.2 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 1 1 NACHT domain RNA_helicase PF00910.22 OAJ18497.1 - 0.0081 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 OAJ18497.1 - 0.0088 16.3 0.1 0.027 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 OAJ18497.1 - 0.009 16.0 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 OAJ18497.1 - 0.0095 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 OAJ18497.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAJ18497.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.14 OAJ18497.1 - 0.022 14.8 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 OAJ18497.1 - 0.022 14.5 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ18497.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Septin PF00735.18 OAJ18497.1 - 0.047 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA PF00004.29 OAJ18497.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 OAJ18497.1 - 0.079 12.7 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 OAJ18497.1 - 0.086 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAJ18497.1 - 0.1 13.0 0.0 0.27 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ18497.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PTS_IIB PF02302.17 OAJ18497.1 - 0.14 12.8 0.0 0.64 10.8 0.0 2.1 2 0 0 2 2 1 0 PTS system, Lactose/Cellobiose specific IIB subunit PTE PF02126.18 OAJ18497.1 - 0.19 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family cobW PF02492.19 OAJ18497.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PNP_UDP_1 PF01048.20 OAJ18498.1 - 3.4e-31 108.3 4.7 2.9e-30 105.3 4.7 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily F-box PF00646.33 OAJ18514.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ18514.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 OAJ18514.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 F-box F-box PF00646.33 OAJ18516.1 - 0.028 14.3 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 F-box domain PIGA PF08288.12 OAJ18518.1 - 9.1e-41 138.4 0.0 1.8e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAJ18518.1 - 7e-28 97.7 1.5 1.2e-27 96.9 1.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ18518.1 - 2.3e-23 82.6 0.0 3.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ18518.1 - 8.2e-21 74.8 0.0 1.7e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ18518.1 - 2.9e-13 50.6 0.3 6.9e-13 49.3 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAJ18518.1 - 1.3e-05 25.2 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAJ18518.1 - 0.00015 22.1 0.0 0.00038 20.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 PIGA PF08288.12 OAJ18522.1 - 1.3e-40 137.9 0.0 2.9e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAJ18522.1 - 4.7e-25 88.5 1.3 9.6e-25 87.5 1.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ18522.1 - 2.4e-23 82.5 0.0 4e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ18522.1 - 4e-21 75.9 0.0 8e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ18522.1 - 3.8e-11 43.7 0.3 3.8e-11 43.7 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAJ18522.1 - 4.9e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 OAJ18522.1 - 2.2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF3579 PF12112.8 OAJ18526.1 - 0.12 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) Tyrosinase PF00264.20 OAJ18529.1 - 1.6e-35 123.4 4.8 2.4e-35 122.8 4.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase G2BR PF18442.1 OAJ18530.1 - 0.33 10.6 5.3 0.87 9.3 5.3 1.7 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) HEAT_EZ PF13513.6 OAJ18542.1 - 4.3e-22 78.2 21.6 5.9e-13 49.0 0.0 9.3 9 2 2 11 11 10 3 HEAT-like repeat HEAT PF02985.22 OAJ18542.1 - 1.6e-16 59.0 15.6 0.0016 18.5 0.0 9.4 11 0 0 11 11 10 4 HEAT repeat HEAT_2 PF13646.6 OAJ18542.1 - 1.2e-14 54.5 2.3 0.00057 20.2 0.0 7.2 5 3 2 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 OAJ18542.1 - 2e-10 41.1 0.0 0.0007 20.1 0.1 4.5 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 OAJ18542.1 - 4e-08 32.8 10.9 0.00047 19.4 0.1 4.8 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 OAJ18542.1 - 1.2e-06 28.7 0.0 0.018 15.1 0.0 4.5 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 OAJ18542.1 - 1.8e-05 24.6 0.0 7.2e-05 22.6 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OAJ18542.1 - 0.00016 21.8 0.1 0.00098 19.3 0.0 2.5 3 0 0 3 3 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 OAJ18542.1 - 0.00019 21.3 0.0 0.71 9.8 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3437) Arm PF00514.23 OAJ18542.1 - 0.001 19.1 3.2 0.87 9.7 0.0 4.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 OAJ18542.1 - 0.0059 16.5 0.1 5.6 6.8 0.0 4.6 4 2 2 6 6 5 1 Domain of unknown function (DUF3385) Ecm29 PF13001.7 OAJ18542.1 - 0.0073 15.0 0.0 0.77 8.4 0.0 3.3 2 1 1 3 3 3 1 Proteasome stabiliser DRIM PF07539.12 OAJ18542.1 - 0.011 14.1 1.0 0.18 10.1 0.1 3.1 4 1 0 4 4 4 0 Down-regulated in metastasis Cnd3 PF12719.7 OAJ18542.1 - 0.028 13.6 0.4 0.54 9.4 0.1 3.0 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 OAJ18542.1 - 0.041 12.4 0.6 0.13 10.8 0.2 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Xpo1 PF08389.12 OAJ18542.1 - 0.085 12.9 0.1 6 6.9 0.0 3.3 2 1 0 2 2 2 0 Exportin 1-like protein TRM PF02005.16 OAJ18543.1 - 4.3e-115 384.9 0.0 2.7e-86 290.1 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Mito_carr PF00153.27 OAJ18544.1 - 2.6e-17 62.5 1.5 1.7e-05 24.6 0.0 5.5 5 0 0 5 5 5 5 Mitochondrial carrier protein Med19 PF10278.9 OAJ18544.1 - 0.008 16.1 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Pkinase PF00069.25 OAJ18545.1 - 2.1e-65 220.7 0.0 2.5e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18545.1 - 5.1e-32 111.2 0.0 6.2e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ18545.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FAD_binding_2 PF00890.24 OAJ18545.1 - 0.019 14.0 0.5 0.5 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pilus_CpaD PF09476.10 OAJ18545.1 - 0.021 14.6 0.8 0.032 14.0 0.8 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Kdo PF06293.14 OAJ18545.1 - 0.051 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1c PF00749.21 OAJ18546.1 - 7.8e-108 360.1 0.0 1.3e-107 359.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAJ18546.1 - 2.5e-36 125.2 0.1 3.9e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 OAJ18546.1 - 0.0063 16.7 0.0 0.064 13.5 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ18546.1 - 0.0096 16.1 0.0 0.038 14.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ18546.1 - 0.017 15.2 0.2 0.043 13.8 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.13 OAJ18546.1 - 0.036 14.1 0.4 0.11 12.6 0.4 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family tRNA-synt_1e PF01406.19 OAJ18546.1 - 0.15 11.4 0.0 0.36 10.1 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CS PF04969.16 OAJ18547.1 - 1.2e-08 35.9 0.0 8.9e-08 33.0 0.0 2.5 3 1 0 3 3 3 1 CS domain Isochorismatase PF00857.20 OAJ18548.1 - 1.2e-22 81.0 0.3 6.2e-15 55.8 0.0 2.7 2 1 0 2 2 2 2 Isochorismatase family zf-ZPR1 PF03367.13 OAJ18549.1 - 4.7e-104 345.0 0.0 8.9e-52 175.1 0.0 2.6 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 OAJ18549.1 - 0.0058 16.6 2.4 0.4 10.7 0.3 2.5 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 OAJ18549.1 - 0.069 13.3 3.4 2.2 8.4 0.1 3.0 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 OAJ18549.1 - 0.18 11.8 2.6 12 6.0 0.1 2.6 2 1 0 2 2 2 0 zinc-ribbons DZR PF12773.7 OAJ18549.1 - 0.33 11.0 7.5 2.6 8.1 0.2 3.3 2 1 1 3 3 3 0 Double zinc ribbon DUF2688 PF10892.8 OAJ18549.1 - 2.5 7.6 5.7 0.4 10.2 0.1 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2688) K_channel_TID PF07941.11 OAJ18549.1 - 2.9 8.4 7.8 5.1 7.6 4.8 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-C2HC5 PF06221.13 OAJ18549.1 - 3.1 7.8 6.3 8.1 6.5 0.1 3.5 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type DnaJ_CXXCXGXG PF00684.19 OAJ18549.1 - 3.4 8.1 8.6 44 4.5 0.1 3.1 2 1 0 2 2 2 0 DnaJ central domain IclR PF01614.18 OAJ18550.1 - 1.5e-07 31.3 3.8 0.02 14.7 0.2 3.6 3 0 0 3 3 3 2 Bacterial transcriptional regulator DUF2857 PF11198.8 OAJ18550.1 - 2.4e-07 30.7 0.0 0.0027 17.5 0.0 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF2857) XkdW PF09636.10 OAJ18550.1 - 0.0011 19.0 7.9 2 8.5 0.1 3.8 4 0 0 4 4 4 1 XkdW protein APG6_N PF17675.1 OAJ18550.1 - 0.0015 19.1 18.7 1.1 9.8 0.5 4.2 2 1 0 4 4 4 2 Apg6 coiled-coil region EF-G-binding_N PF07299.11 OAJ18550.1 - 0.0028 18.2 27.0 0.33 11.5 0.4 6.2 4 3 3 7 7 7 3 Elongation factor G-binding protein, N-terminal DUF5333 PF17267.2 OAJ18550.1 - 0.0051 17.0 0.2 1.6 8.9 0.1 3.7 4 0 0 4 4 4 1 Family of unknown function (DUF5333) HTH_AsnC-type PF13404.6 OAJ18550.1 - 0.016 15.0 2.6 21 5.0 0.0 4.7 5 0 0 5 5 4 0 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 OAJ18550.1 - 0.018 14.6 1.7 20 4.8 0.1 4.5 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding DUF4164 PF13747.6 OAJ18550.1 - 0.022 15.0 22.2 0.45 10.8 1.9 5.1 4 2 1 5 5 5 0 Domain of unknown function (DUF4164) SNF2_assoc PF08455.10 OAJ18550.1 - 0.034 13.2 3.2 4.1 6.3 0.1 3.3 1 1 1 3 3 3 0 Bacterial SNF2 helicase associated DUF327 PF03885.13 OAJ18550.1 - 0.04 13.9 2.5 7.6 6.5 0.3 2.9 3 1 0 3 3 2 0 Protein of unknown function (DUF327) UBA_6 PF18039.1 OAJ18550.1 - 0.042 13.8 0.8 0.93 9.5 0.1 3.6 3 0 0 3 3 2 0 UBA-like domain DUF2312 PF10073.9 OAJ18550.1 - 0.11 12.1 4.5 8.6 6.1 0.0 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Baculo_PEP_C PF04513.12 OAJ18550.1 - 0.12 12.4 15.8 2.8 8.0 0.4 4.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAT PF03127.14 OAJ18550.1 - 0.13 12.6 4.7 3.5 8.0 0.2 3.4 4 0 0 4 4 3 0 GAT domain DUF1615 PF07759.12 OAJ18550.1 - 0.21 10.8 9.6 4.2 6.5 0.1 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF1615) T7SS_ESX_EspC PF10824.8 OAJ18550.1 - 0.26 11.8 18.9 3.9 8.0 0.1 4.7 4 1 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm DUF4559 PF15112.6 OAJ18550.1 - 0.3 10.7 3.8 1.1 8.9 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4559) PTRF_SDPR PF15237.6 OAJ18550.1 - 0.33 10.5 4.1 4.7 6.8 0.0 3.5 4 0 0 4 4 4 0 PTRF/SDPR family SinI PF08671.10 OAJ18550.1 - 0.38 10.6 11.7 4.1 7.3 0.2 4.0 4 0 0 4 4 4 0 Anti-repressor SinI MqsA_antitoxin PF15731.5 OAJ18550.1 - 0.47 10.6 4.6 13 5.9 0.2 3.5 4 0 0 4 4 4 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Spectrin PF00435.21 OAJ18550.1 - 0.51 10.9 15.4 3.1 8.3 0.7 4.4 4 0 0 4 4 4 0 Spectrin repeat Pox_A6 PF04924.12 OAJ18550.1 - 0.62 8.9 3.5 6.9 5.5 0.0 3.0 3 0 0 3 3 3 0 Poxvirus A6 protein YkyA PF10368.9 OAJ18550.1 - 0.65 9.7 8.8 6.4 6.4 0.3 3.6 3 1 0 3 3 3 0 Putative cell-wall binding lipoprotein LeuA_dimer PF08502.10 OAJ18550.1 - 1 9.3 9.4 24 4.8 0.0 4.4 5 0 0 5 5 4 0 LeuA allosteric (dimerisation) domain OmpH PF03938.14 OAJ18550.1 - 1.1 9.6 30.0 0.25 11.7 4.6 4.4 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4854 PF16146.5 OAJ18550.1 - 1.2 9.5 4.6 21 5.5 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4854) COG6 PF06419.11 OAJ18550.1 - 1.4 7.0 9.5 0.64 8.2 0.4 3.0 2 1 2 4 4 4 0 Conserved oligomeric complex COG6 DUF2203 PF09969.9 OAJ18550.1 - 1.7 9.4 16.8 2.1 9.1 0.6 4.0 3 1 2 5 5 5 0 Uncharacterized conserved protein (DUF2203) YicC_N PF03755.13 OAJ18550.1 - 2.7 8.5 12.5 0.78 10.2 0.3 3.9 1 1 1 3 3 3 0 YicC-like family, N-terminal region SlyX PF04102.12 OAJ18550.1 - 5.3 7.7 5.8 4.5 8.0 0.1 3.5 4 1 0 4 4 3 0 SlyX Bestrophin PF01062.21 OAJ18551.1 - 3.8e-17 62.6 0.1 3.4e-09 36.5 0.0 2.2 1 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TSCPD PF12637.7 OAJ18551.1 - 0.025 14.8 0.2 0.095 13.0 0.1 1.9 2 0 0 2 2 2 0 TSCPD domain LPG_synthase_TM PF03706.13 OAJ18551.1 - 0.35 10.4 10.1 0.049 13.2 3.3 2.0 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Cyclin_N PF00134.23 OAJ18552.1 - 7.8e-38 129.1 1.3 7e-37 126.0 1.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ18552.1 - 1.5e-25 89.6 0.3 3.5e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain WRNPLPNID PF15017.6 OAJ18553.1 - 0.002 19.0 3.7 0.0039 18.0 3.7 1.5 1 0 0 1 1 1 1 Putative WW-binding domain and destruction box LapA_dom PF06305.11 OAJ18553.1 - 0.0062 16.3 0.4 0.012 15.5 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 OAJ18554.1 - 1.3e-26 93.2 0.0 4.1e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ18554.1 - 5.3e-16 58.9 0.0 1e-15 58.0 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ18554.1 - 6e-09 36.1 0.2 1.5e-08 34.8 0.2 1.6 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAJ18554.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OAJ18554.1 - 0.013 15.4 0.0 0.21 11.5 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding YjeF_N PF03853.15 OAJ18554.1 - 0.016 15.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 OAJ18554.1 - 0.02 14.8 0.2 0.031 14.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Alanine_zipper PF11839.8 OAJ18554.1 - 2.2 8.7 6.0 0.31 11.4 1.7 1.7 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein GTP_EFTU PF00009.27 OAJ18555.1 - 7.4e-57 192.0 0.1 1.4e-56 191.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ18555.1 - 1.1e-36 125.3 0.1 3.7e-36 123.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 OAJ18555.1 - 2.2e-29 101.3 0.0 4.9e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAJ18555.1 - 1.1e-22 79.9 0.2 2.9e-22 78.5 0.2 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ18555.1 - 4.6e-12 46.1 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ18555.1 - 1.4e-06 28.1 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ribosomal_S10 PF00338.22 OAJ18556.1 - 8.6e-22 77.2 0.0 1.8e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pex14_N PF04695.13 OAJ18556.1 - 0.078 13.6 9.5 0.033 14.8 2.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Helicase_C PF00271.31 OAJ18557.1 - 1.2e-05 25.6 0.0 1.2e-05 25.6 0.0 2.5 2 1 0 2 2 1 1 Helicase conserved C-terminal domain Caldesmon PF02029.15 OAJ18557.1 - 0.00092 18.1 23.3 0.0014 17.5 23.3 1.2 1 0 0 1 1 1 1 Caldesmon Presenilin PF01080.17 OAJ18557.1 - 0.0043 15.9 37.3 0.0091 14.8 37.3 1.4 1 0 0 1 1 1 1 Presenilin DUF572 PF04502.13 OAJ18557.1 - 0.022 14.4 21.2 0.039 13.6 21.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 OAJ18557.1 - 0.044 10.9 30.9 0.065 10.4 30.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 OAJ18557.1 - 0.12 12.2 31.1 0.22 11.3 31.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.18 OAJ18557.1 - 0.2 10.0 0.1 0.28 9.5 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein SLC12 PF03522.15 OAJ18557.1 - 0.64 9.0 41.6 1.1 8.2 41.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 BAF1_ABF1 PF04684.13 OAJ18557.1 - 0.67 8.9 29.9 1.5 7.8 29.9 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FapA PF03961.13 OAJ18557.1 - 3.4 6.2 22.7 2.8 6.4 20.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Hamartin PF04388.12 OAJ18557.1 - 3.5 6.2 47.5 6.1 5.4 47.5 1.3 1 0 0 1 1 1 0 Hamartin protein Baculo_PEP_C PF04513.12 OAJ18558.1 - 0.0029 17.7 4.7 0.023 14.7 0.1 3.1 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus FeoC PF09012.10 OAJ18558.1 - 0.054 13.6 0.0 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator HOASN PF14515.6 OAJ18558.1 - 2.4 8.6 6.6 20 5.6 0.1 3.0 2 1 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices CBF PF03914.17 OAJ18559.1 - 5.2e-43 147.0 0.0 5.2e-43 147.0 0.0 2.9 3 1 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 OAJ18559.1 - 0.0035 17.4 0.1 0.0083 16.2 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 PI-PLC-X PF00388.19 OAJ18560.1 - 6.1e-46 155.6 0.0 9.5e-46 155.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ18560.1 - 8.5e-37 126.0 0.0 2.4e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAJ18560.1 - 0.0061 16.8 0.0 0.022 15.1 0.0 1.9 1 1 0 1 1 1 1 C2 domain Asp2 PF16929.5 OAJ18561.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter FSA_C PF10479.9 OAJ18561.1 - 1.7 6.7 12.4 3.2 5.8 12.4 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus F-box-like PF12937.7 OAJ18562.1 - 1.6e-06 27.9 0.8 3.3e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ18562.1 - 0.0046 16.8 0.4 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 F-box domain Nucleo_P87 PF07267.11 OAJ18562.1 - 0.14 10.9 2.0 0.24 10.2 2.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PI3K_1B_p101 PF10486.9 OAJ18562.1 - 0.17 9.6 4.7 0.25 9.1 4.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_Ag35 PF03286.14 OAJ18562.1 - 2.2 8.0 11.0 0.052 13.3 1.9 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OAJ18562.1 - 4.6 6.9 12.4 0.09 12.4 3.1 2.5 2 0 0 2 2 2 0 FAM176 family Amino_oxidase PF01593.24 OAJ18563.1 - 1.9e-14 53.9 0.0 4.1e-12 46.1 0.0 3.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ18563.1 - 2.2e-11 43.8 0.2 4.5e-11 42.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ18563.1 - 1.5e-08 34.3 0.5 2.9e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ18563.1 - 2e-07 30.9 0.0 2.9e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ18563.1 - 0.00033 19.9 1.7 0.0005 19.3 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ18563.1 - 0.00098 19.6 2.6 0.0033 18.0 1.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAJ18563.1 - 0.0019 17.1 0.9 0.85 8.4 0.6 2.2 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 OAJ18563.1 - 0.002 16.9 0.2 0.0029 16.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 OAJ18563.1 - 0.0043 16.3 1.0 0.0077 15.5 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 OAJ18563.1 - 0.0055 16.0 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAJ18563.1 - 0.036 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ18563.1 - 0.043 12.9 0.2 0.081 12.0 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 OAJ18563.1 - 0.045 14.0 0.2 0.086 13.1 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 OAJ18563.1 - 0.048 13.0 0.2 0.048 13.0 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 OAJ18563.1 - 0.073 12.7 1.0 0.16 11.6 1.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAJ18563.1 - 0.087 12.8 0.1 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 OAJ18563.1 - 0.13 12.3 0.9 0.49 10.4 0.3 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAJ18563.1 - 0.14 12.6 0.2 0.86 10.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 OAJ18563.1 - 0.45 9.5 2.9 0.3 10.1 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Avl9 PF09794.9 OAJ18580.1 - 0.027 13.2 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Transport protein Avl9 RAP1 PF07218.11 OAJ18580.1 - 9 4.4 8.3 12 4.0 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) T2SSC PF11356.8 OAJ18580.1 - 9 6.2 6.5 0.49 10.3 0.8 1.8 2 0 0 2 2 2 0 Type II secretion system protein C PPR_2 PF13041.6 OAJ18581.1 - 7.4e-05 22.9 0.0 0.065 13.4 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family TFIIA PF03153.13 OAJ18581.1 - 6.8 6.6 12.5 13 5.6 12.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ18582.1 - 0.026 14.1 1.1 1.3 8.6 0.9 2.1 2 0 0 2 2 2 0 Spt20 family Pkinase PF00069.25 OAJ18584.1 - 1e-20 74.3 0.0 1.8e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18584.1 - 2e-13 50.3 0.0 7.9e-13 48.3 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 OAJ18584.1 - 0.38 11.2 1.7 5.7 7.5 0.1 3.4 4 0 0 4 4 4 0 HEAT repeat Peptidase_S9 PF00326.21 OAJ18585.1 - 2.8e-31 108.7 0.0 1.1e-30 106.7 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAJ18585.1 - 0.00038 20.1 0.0 0.0027 17.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 OAJ18585.1 - 0.00051 19.8 0.7 0.018 14.7 0.4 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ18585.1 - 0.00091 18.6 0.2 0.057 12.7 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 OAJ18585.1 - 0.0063 15.2 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAJ18585.1 - 0.009 16.6 2.5 0.036 14.7 2.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ18585.1 - 0.013 15.3 0.1 0.091 12.6 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 OAJ18585.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 OAJ18585.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) ZZ PF00569.17 OAJ18586.1 - 2.3e-22 78.5 62.8 6.9e-09 35.4 4.9 5.5 5 0 0 5 5 5 4 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 OAJ18586.1 - 3.7e-21 75.8 0.0 2.8e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 OAJ18586.1 - 5.6e-06 26.6 46.2 2.8e-05 24.4 4.4 5.0 4 0 0 4 4 4 4 C1 domain Aldedh PF00171.22 OAJ18587.1 - 1.9e-11 43.1 0.1 4.4e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family CRR7 PF12095.8 OAJ18587.1 - 0.11 13.0 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1771 PF08590.10 OAJ18587.1 - 0.85 10.0 4.0 0.73 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) HsbA PF12296.8 OAJ18588.1 - 1e-14 55.0 7.5 1e-14 55.0 7.5 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Cyclin_N PF00134.23 OAJ18590.1 - 2.4e-13 49.9 0.0 4.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ18590.1 - 3.1e-09 37.4 0.1 8.3e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin Acyltransferase PF01553.21 OAJ18591.1 - 2.2e-20 72.7 0.0 5.4e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Isochorismatase PF00857.20 OAJ18592.1 - 2.9e-30 105.7 0.0 3.6e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3546 PF12066.8 OAJ18593.1 - 1.7e-17 63.6 0.9 4.2e-17 62.3 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OAJ18593.1 - 2.4e-06 28.1 0.0 2.4e-06 28.1 0.0 2.7 2 0 0 2 2 2 1 Arsenite-resistance protein 2 ADH_N PF08240.12 OAJ18594.1 - 2.7e-26 91.6 4.1 4.8e-26 90.8 4.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ18594.1 - 2.8e-16 59.7 0.1 4.7e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ18594.1 - 0.005 17.9 0.0 0.0076 17.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ18594.1 - 0.028 13.8 0.1 0.045 13.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAJ18594.1 - 0.1 11.9 0.2 0.18 11.1 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MS_channel PF00924.18 OAJ18595.1 - 8.1e-24 84.3 1.0 1.4e-23 83.5 1.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3336 PF11815.8 OAJ18596.1 - 1.1e-46 158.0 1.0 2e-46 157.2 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAJ18596.1 - 6.6e-17 62.4 3.0 7.6e-17 62.2 0.1 2.7 3 1 0 3 3 3 1 Patatin-like phospholipase Nop PF01798.18 OAJ18597.1 - 7.1e-83 277.6 0.0 7.1e-83 277.6 0.0 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ18597.1 - 1.4e-18 67.0 0.1 6.4e-18 64.9 0.1 2.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain SDA1 PF05285.12 OAJ18597.1 - 0.033 13.6 34.4 0.036 13.5 32.3 1.8 2 0 0 2 2 2 0 SDA1 YL1 PF05764.13 OAJ18597.1 - 0.93 9.6 35.5 1.4 8.9 35.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SGT1 PF07093.11 OAJ18597.1 - 2 6.7 18.0 2.8 6.3 18.0 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 OAJ18597.1 - 7.5 4.7 35.0 11 4.2 35.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 OAJ18597.1 - 8.8 6.3 10.6 13 5.7 10.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-3 PF04882.12 OAJ18598.1 - 2e-115 386.5 15.5 3.1e-84 283.6 7.0 2.1 1 1 1 2 2 2 2 Peroxin-3 Fmp27_WPPW PF10359.9 OAJ18598.1 - 0.015 14.1 1.4 0.24 10.2 0.2 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Bap31_Bap29_C PF18035.1 OAJ18598.1 - 0.47 10.5 1.7 11 6.1 0.4 3.1 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fringe PF02434.16 OAJ18599.1 - 3.6e-08 33.2 0.0 5.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Phospholip_A2_1 PF00068.19 OAJ18599.1 - 0.035 14.6 1.3 0.061 13.8 1.3 1.3 1 0 0 1 1 1 0 Phospholipase A2 Galactosyl_T PF01762.21 OAJ18599.1 - 0.059 13.2 0.0 0.18 11.6 0.0 1.6 1 1 1 2 2 2 0 Galactosyltransferase Whi5 PF08528.11 OAJ18600.1 - 6.1e-09 35.3 0.0 9.8e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Whi5 like FAD_binding_3 PF01494.19 OAJ18601.1 - 1.1e-16 61.1 5.4 6.3e-08 32.2 0.3 3.3 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 OAJ18601.1 - 0.0011 18.6 1.3 0.0032 17.1 0.1 2.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase SE PF08491.10 OAJ18601.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 OAJ18601.1 - 0.022 15.0 0.2 0.072 13.3 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ18601.1 - 0.024 15.2 0.1 1.2 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ18601.1 - 0.051 12.6 10.3 0.3 10.1 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein PGP_phosphatase PF09419.10 OAJ18602.1 - 1.8e-38 131.8 0.0 1.8e-33 115.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 OAJ18602.1 - 0.066 13.3 0.1 0.3 11.2 0.1 2.1 2 1 0 2 2 2 0 HAD-hyrolase-like PNISR PF15996.5 OAJ18603.1 - 0.016 15.5 10.5 0.022 15.1 10.5 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Nop53 PF07767.11 OAJ18603.1 - 0.11 11.9 13.0 0.14 11.5 13.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2058 PF09831.9 OAJ18603.1 - 0.33 11.1 11.3 0.41 10.8 11.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RR_TM4-6 PF06459.12 OAJ18603.1 - 0.41 10.4 6.0 0.53 10.1 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rrn6 PF10214.9 OAJ18603.1 - 0.46 8.9 12.5 0.47 8.9 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Miga PF10265.9 OAJ18603.1 - 0.9 8.4 4.5 0.94 8.4 4.5 1.0 1 0 0 1 1 1 0 Mitoguardin Connexin PF00029.19 OAJ18603.1 - 0.92 9.2 2.9 1.2 8.8 2.9 1.2 1 0 0 1 1 1 0 Connexin DUF2828 PF11443.8 OAJ18603.1 - 1.7 6.6 6.7 2.2 6.3 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF3_subunit PF08597.10 OAJ18603.1 - 1.9 8.3 14.9 2.6 7.9 14.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 OAJ18603.1 - 2.7 6.7 7.1 2.9 6.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin STAG PF08514.11 OAJ18603.1 - 3.6 7.5 9.6 24 4.9 9.6 2.0 1 1 0 1 1 1 0 STAG domain Conotoxin PF02950.17 OAJ18603.1 - 8.4 7.5 6.1 4.7 8.3 0.5 2.3 1 1 1 2 2 2 0 Conotoxin PepSY_TM PF03929.16 OAJ18603.1 - 9.3 5.8 6.2 19 4.8 6.2 1.5 1 1 0 1 1 1 0 PepSY-associated TM region SSP160 PF06933.11 OAJ18605.1 - 0.6 8.2 8.8 0.56 8.3 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CNH PF00780.22 OAJ18619.1 - 6.2e-35 121.1 0.0 1.2e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAJ18619.1 - 3.6e-21 76.2 1.0 6.1e-21 75.5 1.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ18619.1 - 0.0023 18.0 0.0 0.0073 16.4 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1768 PF08719.11 OAJ18620.1 - 8.7e-23 81.3 0.6 7.3e-22 78.3 0.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ18620.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.6 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 Abhydrolase_6 PF12697.7 OAJ18620.1 - 0.034 14.7 0.9 0.093 13.3 0.0 2.0 2 1 1 3 3 3 0 Alpha/beta hydrolase family PARP PF00644.20 OAJ18621.1 - 1.5e-06 28.0 0.0 0.00035 20.2 0.0 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 OAJ18622.1 - 4.2e-16 59.6 0.1 6e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UCH PF00443.29 OAJ18624.1 - 9e-39 133.5 0.0 1.4e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ18624.1 - 2.4e-07 30.6 0.1 0.01 15.5 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF5082 PF16888.5 OAJ18624.1 - 0.0086 16.3 2.0 0.023 15.0 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Herpes_BLRF2 PF05812.12 OAJ18624.1 - 0.052 13.7 0.8 0.29 11.3 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DNApol_Exo PF18136.1 OAJ18625.1 - 9.4e-80 267.7 0.0 5.3e-69 232.5 0.0 3.4 2 1 0 2 2 2 2 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAJ18625.1 - 1.9e-46 158.8 0.0 7.4e-46 156.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family A Glyco_hydro_3_C PF01915.22 OAJ18626.1 - 4.1e-50 170.6 0.1 7.9e-50 169.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAJ18626.1 - 1.1e-39 136.7 0.0 1.8e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAJ18626.1 - 1.4e-19 69.9 0.0 2.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain GST_N_3 PF13417.6 OAJ18627.1 - 1.7e-10 41.2 0.1 2.7e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAJ18627.1 - 1.3e-08 35.0 0.2 2.3e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ18627.1 - 1.5e-08 34.8 0.0 2.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ18627.1 - 7e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ18627.1 - 1.7e-06 28.1 0.0 3.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ18627.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAJ18627.1 - 1.9e-06 28.4 0.0 5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAJ18627.1 - 0.033 14.4 0.0 0.056 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Glutaredoxin2_C PF04399.13 OAJ18627.1 - 0.062 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Zn_clus PF00172.18 OAJ18628.1 - 0.03 14.4 4.0 0.049 13.8 4.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain P34-Arc PF04045.14 OAJ18629.1 - 1e-109 365.9 0.0 1.2e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Thy1 PF02511.15 OAJ18629.1 - 0.043 13.6 0.3 0.91 9.3 0.1 2.2 2 0 0 2 2 2 0 Thymidylate synthase complementing protein XRN_M PF17846.1 OAJ18630.1 - 1.7e-105 353.5 0.7 5.1e-105 352.0 0.7 1.6 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OAJ18630.1 - 5.8e-91 304.2 0.0 1.2e-90 303.2 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 OAJ18630.1 - 3.7e-70 235.6 0.0 7.4e-70 234.6 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 OAJ18630.1 - 1.5e-22 79.6 0.0 3.9e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 OAJ18630.1 - 6e-19 67.9 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain DBR1 PF05011.13 OAJ18630.1 - 0.034 14.6 0.0 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain PPR PF01535.20 OAJ18631.1 - 0.039 14.2 0.0 0.23 11.8 0.0 2.4 2 0 0 2 2 2 0 PPR repeat TPR_7 PF13176.6 OAJ18631.1 - 0.056 13.5 0.3 0.64 10.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Dfp1_Him1_M PF08630.10 OAJ18633.1 - 5.6e-33 113.9 0.0 1.4e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAJ18633.1 - 2.4e-19 69.2 1.3 4.6e-19 68.3 1.3 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 OAJ18633.1 - 0.0032 17.4 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.7 OAJ18633.1 - 0.028 14.8 0.3 0.06 13.7 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) BRCT PF00533.26 OAJ18633.1 - 0.039 14.3 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SSF PF00474.17 OAJ18634.1 - 1.1e-19 70.7 20.8 1.9e-19 69.9 20.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family S-AdoMet_synt_C PF02773.16 OAJ18635.1 - 7.9e-66 220.3 0.2 1.7e-65 219.1 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAJ18635.1 - 4.4e-47 159.3 0.0 8.4e-47 158.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAJ18635.1 - 7.9e-45 151.6 0.2 1.6e-44 150.6 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OAJ18635.1 - 0.033 13.0 0.1 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Hira PF07569.11 OAJ18645.1 - 0.38 10.4 2.5 0.39 10.4 1.0 1.7 1 1 0 2 2 2 0 TUP1-like enhancer of split C166 PF17615.2 OAJ18646.1 - 0.0015 18.7 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function TPR_12 PF13424.6 OAJ18647.1 - 9.5 6.6 27.4 1.8 8.9 0.8 7.1 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18648.1 - 4e-06 27.0 15.2 0.46 10.8 0.2 6.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18648.1 - 0.8 10.7 19.5 38 5.5 0.1 7.7 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18648.1 - 2.3 8.5 20.8 25 5.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18651.1 - 0.0033 17.7 15.6 34 4.8 0.1 6.9 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18651.1 - 0.068 13.3 10.7 34 4.9 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18651.1 - 0.13 12.2 8.7 18 5.4 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18652.1 - 0.0053 17.0 10.5 2 8.7 0.1 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18652.1 - 0.011 15.8 7.1 13 6.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18652.1 - 0.047 13.9 1.4 22 5.6 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat DPM3 PF08285.11 OAJ18653.1 - 3.3 8.0 4.5 0.8 9.9 0.3 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TPR_2 PF07719.17 OAJ18654.1 - 0.058 13.5 2.2 90 3.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18654.1 - 0.1 12.8 0.6 29 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ18654.1 - 0.35 10.8 6.0 4.8 7.2 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18654.1 - 1.8 9.6 8.8 12 7.0 0.1 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 OAJ18655.1 - 5.7e-49 166.1 1.0 5.7e-49 166.1 1.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ18655.1 - 6.4e-46 156.4 5.3 6.9e-45 153.0 3.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ18655.1 - 4.1e-21 76.2 0.1 2.6e-07 31.1 0.3 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ18655.1 - 4.1e-18 64.8 0.0 9.4e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ18655.1 - 4.9e-16 58.6 0.0 9.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ18655.1 - 1.5e-05 24.9 1.2 0.00042 20.2 1.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ18655.1 - 0.0039 17.6 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2148 PF09918.9 OAJ18655.1 - 2.1 8.4 6.5 20 5.3 1.3 2.9 2 0 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) adh_short_C2 PF13561.6 OAJ18656.1 - 7.3e-53 179.5 3.9 1.9e-42 145.4 2.2 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ18656.1 - 4.6e-46 156.8 2.0 5.8e-46 156.4 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ18656.1 - 2.4e-14 53.7 2.2 1.2e-13 51.4 2.2 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 OAJ18656.1 - 0.0027 17.6 0.6 0.0047 16.8 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ18656.1 - 0.011 16.4 0.2 0.023 15.4 0.2 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 OAJ18656.1 - 0.018 14.4 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ18656.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 OAJ18656.1 - 0.065 13.2 2.9 0.54 10.2 2.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Inhibitor_I78 PF11720.8 OAJ18656.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I78 family GDA1_CD39 PF01150.17 OAJ18657.1 - 1.4e-74 251.3 0.0 3.4e-58 197.3 0.0 3.0 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OAJ18657.1 - 0.011 15.2 0.0 0.61 9.5 0.0 2.1 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Vta1 PF04652.16 OAJ18658.1 - 5e-51 172.5 0.2 5e-51 172.5 0.2 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAJ18658.1 - 5.8e-14 51.5 1.0 5.8e-14 51.5 1.0 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain TPR_12 PF13424.6 OAJ18663.1 - 0.0088 16.3 7.9 11 6.3 0.1 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat MEDS PF14417.6 OAJ18663.1 - 0.066 13.0 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TPR_10 PF13374.6 OAJ18663.1 - 0.29 11.1 9.7 0.66 9.9 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18664.1 - 5.1e-05 23.5 2.3 0.0067 16.7 0.3 4.7 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18664.1 - 8.4e-05 22.4 1.8 0.77 10.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18664.1 - 9e-05 22.1 0.2 0.33 10.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18664.1 - 0.0007 19.6 0.2 4.7 7.7 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ18664.1 - 0.11 12.6 1.0 17 5.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ18664.1 - 0.13 12.3 0.6 1.4e+02 2.9 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18664.1 - 0.25 12.3 3.6 1.3e+02 3.8 0.0 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat SF3b1 PF08920.10 OAJ18665.1 - 4.7e-25 88.4 6.9 5e-25 88.3 3.6 3.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 OAJ18665.1 - 4.3e-13 49.5 9.9 0.0046 17.4 0.0 7.7 6 2 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 OAJ18665.1 - 4e-10 40.0 11.5 0.00088 19.6 0.2 8.1 4 2 5 9 9 9 2 HEAT repeats DUF3385 PF11865.8 OAJ18665.1 - 2e-07 31.1 1.6 0.0058 16.6 0.1 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) NUC173 PF08161.12 OAJ18665.1 - 7.9e-06 25.7 0.9 0.44 10.2 0.0 4.3 4 1 1 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 OAJ18665.1 - 1.9e-05 23.4 2.0 0.00054 18.7 0.1 2.9 2 1 1 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 OAJ18665.1 - 2.4e-05 24.8 0.4 1.6 9.4 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ18665.1 - 4.5e-05 23.6 1.1 17 5.4 0.0 5.6 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAJ18665.1 - 8.4e-05 22.2 0.6 0.28 10.7 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal HEAT PF02985.22 OAJ18665.1 - 0.00014 21.8 12.5 2.7 8.5 0.1 8.4 10 0 0 10 10 9 1 HEAT repeat Dopey_N PF04118.14 OAJ18665.1 - 0.00091 18.4 1.0 0.025 13.7 0.0 3.1 3 0 0 3 3 3 1 Dopey, N-terminal MMS19_C PF12460.8 OAJ18665.1 - 0.0048 16.1 0.0 1.7 7.6 0.0 3.6 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal LIDHydrolase PF10230.9 OAJ18665.1 - 0.011 15.3 0.1 0.042 13.4 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase UME PF08064.13 OAJ18665.1 - 0.044 13.7 0.0 4 7.4 0.0 4.0 4 0 0 4 4 4 0 UME (NUC010) domain MOZ_SAS PF01853.18 OAJ18666.1 - 5.4e-79 264.0 0.0 8.4e-79 263.4 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ18666.1 - 3.2e-23 81.1 2.8 5.6e-23 80.3 2.8 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAJ18666.1 - 1e-18 66.9 0.1 3.3e-18 65.3 0.1 1.9 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAJ18666.1 - 0.0032 17.9 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNA_pol_3_Rpc31 PF11705.8 OAJ18666.1 - 0.01 16.1 2.1 0.01 16.1 2.1 3.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Acetyltransf_1 PF00583.25 OAJ18666.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Imm5 PF14423.6 OAJ18666.1 - 0.36 11.0 9.5 0.021 15.1 3.5 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 F-protein PF00469.20 OAJ18666.1 - 0.4 10.2 4.0 1.1 8.8 4.0 1.7 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ORC6 PF05460.13 OAJ18666.1 - 0.46 9.7 11.6 1 8.6 11.6 1.6 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM60A PF15396.6 OAJ18666.1 - 1.2 9.2 7.8 3.2 7.7 7.8 1.8 1 0 0 1 1 1 0 Protein Family FAM60A Hamartin PF04388.12 OAJ18666.1 - 1.4 7.5 10.5 1.9 7.1 10.5 1.3 1 0 0 1 1 1 0 Hamartin protein Rtf2 PF04641.12 OAJ18666.1 - 8.9 5.6 13.0 42 3.4 13.0 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4551 PF15087.6 OAJ18666.1 - 9 5.0 9.2 15 4.2 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Phosphoesterase PF04185.14 OAJ18667.1 - 6.9e-82 275.5 0.0 9.4e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family RicinB_lectin_2 PF14200.6 OAJ18667.1 - 0.025 15.3 5.6 1.4 9.7 0.0 3.3 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Cu-oxidase_2 PF07731.14 OAJ18668.1 - 2.7e-34 117.9 7.0 2.4e-33 114.8 2.1 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ18668.1 - 1.9e-30 106.1 0.0 1.3e-29 103.4 0.0 2.3 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAJ18668.1 - 9.6e-28 96.6 3.5 2.3e-18 66.3 0.1 3.5 4 0 0 4 4 4 2 Multicopper oxidase FUN14 PF04930.15 OAJ18669.1 - 5.1e-20 71.7 1.3 1.6e-19 70.1 0.8 1.9 2 0 0 2 2 2 1 FUN14 family TMEM141 PF15110.6 OAJ18669.1 - 0.022 15.3 0.8 0.099 13.2 0.2 2.1 2 0 0 2 2 2 0 TMEM141 protein family p450 PF00067.22 OAJ18670.1 - 8.6e-72 242.3 0.0 1.1e-71 242.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C12 PF01088.21 OAJ18686.1 - 2.4e-58 197.4 0.0 2.8e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MCM PF00493.23 OAJ18687.1 - 3e-97 324.1 0.1 4.3e-97 323.6 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ18687.1 - 1e-32 112.7 0.0 1.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ18687.1 - 1.1e-23 83.4 0.5 2.7e-23 82.2 0.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ18687.1 - 1.3e-15 57.8 0.0 3.6e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ18687.1 - 1.3e-07 31.3 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ18687.1 - 0.0029 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PBP1_TM PF14812.6 OAJ18687.1 - 0.0043 17.4 6.9 0.012 16.0 5.5 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma54_activat PF00158.26 OAJ18687.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ18687.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CENP-B_dimeris PF09026.10 OAJ18687.1 - 0.13 12.7 8.4 0.078 13.4 3.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 OAJ18687.1 - 3.8 6.6 8.5 0.64 9.1 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) SPX PF03105.19 OAJ18688.1 - 0.016 15.2 0.9 0.024 14.5 0.9 1.2 1 0 0 1 1 1 0 SPX domain DUF4692 PF15763.5 OAJ18688.1 - 0.14 12.6 0.9 0.32 11.4 0.9 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sds3 PF08598.11 OAJ18689.1 - 3.4e-08 33.7 6.2 3.4e-08 33.7 6.2 2.3 2 0 0 2 2 2 1 Sds3-like Baculo_PP31 PF05311.11 OAJ18689.1 - 0.033 13.7 0.4 0.033 13.7 0.4 2.4 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SMYLE_N PF18615.1 OAJ18689.1 - 2.3 7.7 12.5 4.4 6.8 12.5 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF1387 PF07139.11 OAJ18689.1 - 4.9 6.8 21.1 13 5.5 21.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PX PF00787.24 OAJ18690.1 - 2.4e-25 88.7 0.1 4.5e-25 87.8 0.1 1.5 1 0 0 1 1 1 1 PX domain Sec63 PF02889.16 OAJ18691.1 - 8.9e-18 64.4 0.0 6.7e-17 61.5 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 OAJ18691.1 - 1.4e-15 57.1 0.3 3.1e-15 56.0 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Utp12 PF04003.12 OAJ18692.1 - 1.9e-18 66.7 2.4 3.5e-18 65.9 2.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family SAP130_C PF16014.5 OAJ18692.1 - 0.28 10.3 5.5 1 8.4 0.1 2.2 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus DUF202 PF02656.15 OAJ18693.1 - 6.8e-08 32.8 5.6 6.8e-08 32.8 5.6 3.0 2 2 0 2 2 2 1 Domain of unknown function (DUF202) EVE PF01878.18 OAJ18694.1 - 1.3e-36 125.7 0.3 4.7e-36 124.0 0.0 2.0 2 1 0 2 2 2 1 EVE domain Lactamase_B_2 PF12706.7 OAJ18694.1 - 0.054 13.0 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.25 OAJ18695.1 - 1.5e-65 221.2 0.0 2.4e-65 220.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18695.1 - 7.2e-38 130.3 0.0 1.4e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ18695.1 - 0.0024 16.7 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ18695.1 - 0.048 13.0 0.0 0.093 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 OAJ18695.1 - 0.1 12.2 0.1 0.31 10.6 0.0 1.7 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 OAJ18695.1 - 0.11 12.5 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ18695.1 - 0.15 11.1 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Methyltransf_28 PF02636.17 OAJ18695.1 - 0.18 11.4 0.0 4.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lipase_3 PF01764.25 OAJ18696.1 - 6.9e-13 48.7 0.0 2.9e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) BUD22 PF09073.10 OAJ18696.1 - 0.029 13.7 18.1 0.067 12.5 18.1 1.5 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ18696.1 - 0.1 10.8 14.1 0.15 10.3 14.1 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 OAJ18696.1 - 2.6 6.7 7.9 6.2 5.5 7.9 1.6 1 0 0 1 1 1 0 Presenilin Pex24p PF06398.11 OAJ18697.1 - 3.4e-33 115.1 0.0 1.1e-26 93.8 0.0 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin PTP_tm PF18861.1 OAJ18699.1 - 0.03 14.3 0.4 0.053 13.5 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Mid2 PF04478.12 OAJ18699.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Pro_isomerase PF00160.21 OAJ18700.1 - 2.6e-50 170.8 0.0 2.9e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HAD_2 PF13419.6 OAJ18701.1 - 5.6e-10 39.6 0.0 1.1e-08 35.4 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ18701.1 - 2.8e-07 30.5 0.0 6.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Aminotran_1_2 PF00155.21 OAJ18703.1 - 4.8e-54 183.9 0.0 1.1e-53 182.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ18703.1 - 0.085 12.1 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase RNA_pol_Rpb1_1 PF04997.12 OAJ18704.1 - 6e-88 295.2 0.1 9.3e-88 294.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 OAJ18704.1 - 9.3e-82 274.4 0.2 2e-81 273.4 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ18704.1 - 1.3e-68 230.5 0.0 2.2e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ18704.1 - 2.8e-38 131.3 0.0 6.8e-38 130.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAJ18704.1 - 1.3e-27 95.8 0.0 3.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Get5_C PF18514.1 OAJ18704.1 - 0.093 12.5 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Get5 C-terminal domain zf-ribbon_3 PF13248.6 OAJ18704.1 - 0.62 9.5 3.7 6.2 6.4 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 OAJ18704.1 - 1 10.1 3.2 2.7 8.8 3.2 1.7 1 0 0 1 1 1 0 zinc-ribbon family TT_ORF2 PF02957.15 OAJ18705.1 - 0.34 11.8 6.1 13 6.8 1.1 2.9 2 0 0 2 2 2 0 TT viral ORF2 DUF3510 PF12022.8 OAJ18705.1 - 1.1 9.6 3.3 0.74 10.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Arm PF00514.23 OAJ18705.1 - 9.1 6.5 7.5 67 3.7 0.4 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 OAJ18706.1 - 7.9e-72 237.3 7.2 1.5e-23 82.5 0.0 4.4 4 1 0 4 4 4 4 Mitochondrial carrier protein GAD-like PF08887.11 OAJ18706.1 - 0.013 15.2 0.2 4.2 7.2 0.1 2.4 2 0 0 2 2 2 0 GAD-like domain Serine_protease PF18405.1 OAJ18706.1 - 0.016 14.3 0.3 0.19 10.9 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease LSM PF01423.22 OAJ18707.1 - 2.1e-14 53.0 0.0 2.7e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ18707.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Hfq protein ERG4_ERG24 PF01222.17 OAJ18708.1 - 2.6e-122 408.7 20.6 3.1e-122 408.4 20.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_S26 PF10502.9 OAJ18709.1 - 5.4e-08 32.7 0.0 9.9e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAJ18709.1 - 6.8e-05 22.8 0.0 0.00031 20.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Nipped-B_C PF12830.7 OAJ18710.1 - 1.6e-48 165.2 0.8 1.2e-47 162.3 0.7 2.7 3 1 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 OAJ18710.1 - 1.5e-09 38.0 1.2 2.5e-08 34.1 0.1 3.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 OAJ18710.1 - 5.6e-06 26.7 14.0 0.95 9.9 1.2 5.7 6 0 0 6 6 6 4 HEAT repeats Cnd1 PF12717.7 OAJ18710.1 - 0.00064 19.8 0.3 0.0028 17.7 0.2 2.2 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAJ18710.1 - 0.3 11.6 1.5 2.6 8.7 0.6 3.3 2 1 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.20 OAJ18710.1 - 0.32 9.5 9.5 7 5.1 5.3 3.6 2 1 0 2 2 2 0 Adaptin N terminal region PRP3 PF08572.10 OAJ18711.1 - 1e-66 224.9 9.1 1.9e-66 224.0 9.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAJ18711.1 - 4.6e-34 117.6 0.6 8.6e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Pannexin_like PF12534.8 OAJ18711.1 - 2 7.5 3.3 3.3 6.7 3.3 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Cut8 PF08559.10 OAJ18712.1 - 1.5e-12 47.6 0.0 4.8e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein AAA PF00004.29 OAJ18713.1 - 1.3e-40 138.9 0.0 2.4e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAJ18713.1 - 7.7e-28 96.3 0.3 3.4e-27 94.2 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAJ18713.1 - 7.2e-22 77.2 8.6 7.2e-22 77.2 8.6 1.7 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAJ18713.1 - 2.4e-08 33.6 0.0 4.8e-07 29.5 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OAJ18713.1 - 2.4e-05 24.8 0.1 0.0024 18.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 OAJ18713.1 - 0.00012 21.4 0.4 0.00025 20.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 OAJ18713.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ18713.1 - 0.0002 21.3 0.0 0.00064 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ18713.1 - 0.00027 20.7 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAJ18713.1 - 0.00037 20.8 0.1 0.04 14.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ18713.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAJ18713.1 - 0.0009 19.6 0.0 0.025 14.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAJ18713.1 - 0.0021 18.1 0.1 0.0076 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAJ18713.1 - 0.0033 16.6 0.0 0.0069 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 OAJ18713.1 - 0.0042 17.2 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 OAJ18713.1 - 0.012 16.0 0.1 0.041 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAJ18713.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAJ18713.1 - 0.014 15.0 0.1 0.75 9.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 OAJ18713.1 - 0.03 14.9 0.3 0.076 13.6 0.0 2.0 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 OAJ18713.1 - 0.04 13.2 0.0 4.9 6.4 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.6 OAJ18713.1 - 0.041 13.6 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAJ18713.1 - 0.073 12.8 0.0 0.47 10.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 OAJ18713.1 - 0.085 11.7 0.0 0.89 8.4 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase NACHT PF05729.12 OAJ18713.1 - 0.15 11.9 0.1 0.83 9.6 0.0 2.1 2 1 1 3 3 2 0 NACHT domain AAA_7 PF12775.7 OAJ18713.1 - 0.17 11.4 0.0 0.41 10.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 OAJ18713.1 - 0.22 10.9 1.2 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 OAJ18713.1 - 0.25 11.2 1.6 3.4 7.5 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PEMT PF04191.13 OAJ18714.1 - 3.3e-22 78.9 0.9 9.6e-22 77.4 0.9 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Tetraspanin PF00335.20 OAJ18714.1 - 0.16 11.7 1.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family Titin_Z PF09042.11 OAJ18714.1 - 2.9 7.9 6.5 5.4 7.1 6.5 1.3 1 0 0 1 1 1 0 Titin Z PH_10 PF15411.6 OAJ18733.1 - 1e-21 77.5 0.0 1.8e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.6 OAJ18733.1 - 1.9e-07 31.1 0.0 2e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ18733.1 - 1.2e-06 28.8 0.0 0.0059 16.9 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain PP2C PF00481.21 OAJ18734.1 - 3.2e-82 276.0 0.5 6.2e-82 275.1 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.25 OAJ18735.1 - 2.5e-38 131.9 0.0 4.4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18735.1 - 4.9e-09 35.9 0.0 7.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.10 OAJ18735.1 - 1.9e-05 23.4 0.0 0.063 11.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.23 OAJ18735.1 - 2.3e-05 24.5 0.0 7.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ18735.1 - 0.0033 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OAJ18735.1 - 0.014 14.7 0.0 0.17 11.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 OAJ18736.1 - 1.2e-33 116.3 0.0 3.7e-33 114.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ18736.1 - 5.4e-18 65.4 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ18736.1 - 1.4e-16 60.5 1.1 2.9e-16 59.4 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ18736.1 - 4.9e-08 33.2 0.0 9.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ18736.1 - 0.058 13.7 2.5 0.96 9.7 0.8 3.1 2 1 0 2 2 2 0 AAA domain QWRF PF04484.12 OAJ18736.1 - 6.5 6.4 13.2 24 4.5 13.2 1.9 1 0 0 1 1 1 0 QWRF family Sugar_tr PF00083.24 OAJ18737.1 - 2.5e-103 346.4 17.3 2.9e-103 346.2 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ18737.1 - 2.9e-26 92.3 23.8 4.3e-25 88.4 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FA_hydroxylase PF04116.13 OAJ18738.1 - 5.2e-23 81.9 20.3 5.2e-23 81.9 20.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.19 OAJ18738.1 - 0.26 11.9 3.5 0.44 11.2 3.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein LOR PF04525.12 OAJ18739.1 - 2.5e-27 95.7 0.0 3.2e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related SNF2_N PF00176.23 OAJ18740.1 - 4.8e-57 193.3 0.0 7.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ18740.1 - 9.3e-15 54.9 0.0 2.1e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ18740.1 - 2.1e-10 40.9 0.0 4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ18740.1 - 4.8e-07 29.7 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAJ18740.1 - 1.1e-06 28.0 0.0 2.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 OAJ18740.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 OAJ18740.1 - 0.013 14.4 0.0 0.079 11.8 0.0 2.1 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 AAA_22 PF13401.6 OAJ18740.1 - 0.2 11.9 0.6 2.2 8.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain Cwf_Cwc_15 PF04889.12 OAJ18740.1 - 1.1 8.9 4.4 2.5 7.7 4.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_8 PF13181.6 OAJ18741.1 - 4.5e-27 92.0 10.6 3.3e-05 23.8 0.1 8.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18741.1 - 2.9e-26 90.2 12.9 1.1e-05 25.0 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18741.1 - 3.2e-22 76.8 21.4 0.0017 18.3 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC8 PF04049.13 OAJ18741.1 - 1.1e-17 64.3 0.8 6.5e-17 61.9 0.8 2.2 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 OAJ18741.1 - 1.5e-16 59.7 18.9 0.00024 21.6 0.2 8.9 6 3 4 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ18741.1 - 1.4e-12 47.0 1.2 0.0077 16.5 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ18741.1 - 1.2e-10 41.4 8.5 0.0049 17.1 0.6 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 OAJ18741.1 - 1.7e-10 40.4 3.7 0.00047 19.8 0.0 4.3 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.6 OAJ18741.1 - 4.4e-09 36.7 10.4 0.0092 16.5 0.1 6.6 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ18741.1 - 3.1e-08 33.8 18.3 0.0016 18.7 2.3 7.4 5 1 4 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ18741.1 - 1.1e-06 28.6 7.0 0.0072 16.4 0.1 5.1 2 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18741.1 - 1.3e-06 29.0 19.9 0.0022 18.6 0.1 6.8 4 1 5 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ18741.1 - 1.4e-06 27.9 17.1 0.0067 16.4 0.1 6.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ18741.1 - 2.7e-06 26.8 4.0 0.014 14.7 0.1 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ18741.1 - 0.00017 22.0 15.7 17 6.3 0.0 8.7 9 1 1 10 10 8 0 Tetratricopeptide repeat ChAPs PF09295.10 OAJ18741.1 - 0.002 17.2 0.0 0.13 11.2 0.0 2.6 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 OAJ18741.1 - 0.0072 15.8 0.0 0.38 10.1 0.0 3.0 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 OAJ18741.1 - 0.048 13.5 13.7 0.53 10.2 0.2 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Inhibitor_Mig-6 PF11555.8 OAJ18741.1 - 0.087 12.9 0.4 0.2 11.8 0.4 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 PspB PF06667.12 OAJ18741.1 - 1.3 9.1 3.0 6.4 6.9 0.1 3.0 3 0 0 3 3 3 0 Phage shock protein B UQ_con PF00179.26 OAJ18742.1 - 2e-41 140.9 0.0 2.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ18742.1 - 0.018 15.3 0.3 0.024 14.9 0.3 1.3 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 OAJ18742.1 - 0.035 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 OAJ18742.1 - 0.037 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B SDA1 PF05285.12 OAJ18743.1 - 1.7e-80 271.1 41.2 1.7e-80 271.1 41.2 3.1 3 1 0 3 3 3 2 SDA1 NUC130_3NT PF08158.12 OAJ18743.1 - 1.2e-15 57.6 0.3 2.4e-15 56.6 0.3 1.6 1 0 0 1 1 1 1 NUC130/3NT domain Spt20 PF12090.8 OAJ18744.1 - 0.0022 17.6 38.4 0.0034 17.0 38.4 1.2 1 0 0 1 1 1 1 Spt20 family Endostatin PF06482.11 OAJ18744.1 - 0.0062 16.0 9.1 0.009 15.5 9.1 1.3 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin TFIIA PF03153.13 OAJ18744.1 - 0.017 15.1 36.4 0.024 14.6 36.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Otopetrin PF03189.13 OAJ18744.1 - 0.019 13.8 2.9 0.02 13.7 2.9 1.1 1 0 0 1 1 1 0 Otopetrin CCDC53 PF10152.9 OAJ18744.1 - 0.022 15.2 10.6 0.036 14.5 10.6 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex eIF-3_zeta PF05091.12 OAJ18744.1 - 0.031 13.3 19.5 0.043 12.8 19.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 OAJ18744.1 - 0.045 13.0 11.8 0.059 12.6 11.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.9 OAJ18744.1 - 0.055 11.7 23.3 0.068 11.5 23.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PepSY_TM PF03929.16 OAJ18744.1 - 0.093 12.4 3.2 0.14 11.8 3.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM region SRP-alpha_N PF04086.13 OAJ18744.1 - 0.097 12.6 14.1 0.16 11.9 14.1 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 OAJ18744.1 - 0.48 8.9 13.8 0.6 8.6 13.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF4106 PF13388.6 OAJ18744.1 - 0.62 9.2 24.0 0.48 9.6 22.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) SOG2 PF10428.9 OAJ18744.1 - 0.78 8.9 15.8 1 8.5 15.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.13 OAJ18744.1 - 0.85 10.3 25.0 1.4 9.5 25.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 OAJ18744.1 - 0.86 9.6 17.1 1.4 9.0 17.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4770 PF15994.5 OAJ18744.1 - 0.93 9.7 12.3 1.5 9.0 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Ndc1_Nup PF09531.10 OAJ18744.1 - 1.4 7.5 12.1 1.9 7.1 12.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Velvet PF11754.8 OAJ18744.1 - 1.5 8.7 16.6 2.4 8.0 16.6 1.2 1 0 0 1 1 1 0 Velvet factor TMEM51 PF15345.6 OAJ18744.1 - 1.7 8.5 11.0 2.5 7.9 11.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Presenilin PF01080.17 OAJ18744.1 - 2.2 7.0 21.1 3 6.5 21.1 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 OAJ18744.1 - 3.4 7.7 14.3 5.3 7.0 14.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SLC12 PF03522.15 OAJ18744.1 - 3.9 6.4 18.1 6 5.8 18.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Serinc PF03348.15 OAJ18744.1 - 4.6 6.1 4.6 7 5.5 4.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) GREB1 PF15782.5 OAJ18744.1 - 5.9 3.9 18.0 7.6 3.5 18.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AF-4 PF05110.13 OAJ18744.1 - 5.9 4.9 25.0 7.5 4.5 25.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Hid1 PF12722.7 OAJ18744.1 - 9.5 4.2 20.0 13 3.8 20.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EMC3_TMCO1 PF01956.16 OAJ18744.1 - 9.8 5.9 7.5 14 5.3 7.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pinin_SDK_memA PF04696.13 OAJ18745.1 - 4.7e-11 42.9 6.5 4.7e-11 42.9 6.5 3.0 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region TPR_MLP1_2 PF07926.12 OAJ18745.1 - 0.31 11.1 13.5 0.061 13.4 3.7 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 OAJ18745.1 - 2 8.6 15.2 0.42 10.8 6.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fmp27_WPPW PF10359.9 OAJ18745.1 - 7.2 5.3 9.0 2.1 7.1 1.9 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA PF00004.29 OAJ18746.1 - 1.4e-96 320.0 0.0 3e-47 160.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ18746.1 - 5e-25 87.1 8.8 2e-12 46.7 0.4 3.0 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 OAJ18746.1 - 2.8e-21 75.5 0.2 9.9e-21 73.7 0.1 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OAJ18746.1 - 1.9e-14 53.7 0.1 2e-05 24.4 0.0 3.7 3 2 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAJ18746.1 - 1.9e-13 50.9 0.0 4.2e-07 30.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ18746.1 - 4.1e-12 46.4 0.0 6.6e-06 26.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 OAJ18746.1 - 2.1e-11 44.0 0.3 2.7e-05 24.2 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 OAJ18746.1 - 1.6e-10 40.6 0.0 3.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 OAJ18746.1 - 4.1e-10 40.3 0.6 0.0016 18.9 0.0 4.5 3 2 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 OAJ18746.1 - 2.6e-09 36.8 0.1 0.0019 17.5 0.0 2.6 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OAJ18746.1 - 6.6e-09 36.2 0.1 0.021 15.1 0.0 4.0 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAJ18746.1 - 4.7e-08 32.7 0.4 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ18746.1 - 3.8e-07 30.0 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 OAJ18746.1 - 5.2e-07 29.6 0.4 4.7e-06 26.5 0.1 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 OAJ18746.1 - 5.8e-07 30.1 0.0 0.011 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OAJ18746.1 - 1.1e-06 28.7 0.0 0.022 14.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 OAJ18746.1 - 1.3e-06 28.7 0.0 0.016 15.5 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 OAJ18746.1 - 1.7e-06 27.6 0.1 0.016 14.8 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 OAJ18746.1 - 4.8e-06 26.1 0.3 0.95 8.8 0.0 3.5 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 OAJ18746.1 - 6.5e-06 25.4 0.2 0.0064 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OAJ18746.1 - 8.5e-06 26.1 0.0 0.084 13.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 OAJ18746.1 - 1.3e-05 24.5 0.0 0.003 16.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAJ18746.1 - 1.7e-05 24.5 3.3 0.22 11.1 0.1 4.3 3 2 1 4 4 4 1 AAA domain Sigma54_activat PF00158.26 OAJ18746.1 - 1.8e-05 24.5 0.0 0.36 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 OAJ18746.1 - 2.5e-05 24.8 0.0 0.13 12.7 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 OAJ18746.1 - 3.3e-05 23.7 0.1 0.19 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.18 OAJ18746.1 - 5.4e-05 23.1 0.0 0.36 10.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.16 OAJ18746.1 - 0.0001 21.9 0.2 0.4 10.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 OAJ18746.1 - 0.00011 22.6 0.1 0.91 10.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain ResIII PF04851.15 OAJ18746.1 - 0.00016 21.7 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 OAJ18746.1 - 0.00017 21.6 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 OAJ18746.1 - 0.00022 21.1 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 OAJ18746.1 - 0.00032 20.6 0.1 1.2 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 OAJ18746.1 - 0.00057 19.8 0.3 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 OAJ18746.1 - 0.00072 19.4 0.0 0.15 11.7 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OAJ18746.1 - 0.0011 18.3 0.0 1.3 8.2 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 OAJ18746.1 - 0.0015 18.3 0.7 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 OAJ18746.1 - 0.0021 18.2 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAJ18746.1 - 0.0022 18.0 0.1 3.1 7.7 0.0 3.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OAJ18746.1 - 0.0023 18.3 2.0 2.3 8.6 0.0 3.8 4 1 1 5 5 3 1 AAA domain NB-ARC PF00931.22 OAJ18746.1 - 0.0062 15.8 0.0 0.6 9.3 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain DUF2075 PF09848.9 OAJ18746.1 - 0.007 15.7 2.5 1.2 8.3 0.0 2.8 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 OAJ18746.1 - 0.018 15.0 0.4 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 NTPase UFD1 PF03152.14 OAJ18746.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 IPT PF01745.16 OAJ18746.1 - 0.025 14.0 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase T2SSE PF00437.20 OAJ18746.1 - 0.03 13.4 0.0 0.85 8.6 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 OAJ18746.1 - 0.03 14.0 0.3 4.7 6.9 0.0 3.0 3 0 0 3 3 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 OAJ18746.1 - 0.04 12.8 0.0 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase KAP_NTPase PF07693.14 OAJ18746.1 - 0.06 12.6 0.0 0.65 9.2 0.0 2.4 2 1 0 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 OAJ18746.1 - 0.23 10.4 0.1 8.5 5.2 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region IBN_N PF03810.19 OAJ18747.1 - 6.7e-13 48.4 0.0 9.3e-12 44.7 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 OAJ18747.1 - 7.5e-08 31.6 0.0 1.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.6 OAJ18747.1 - 3.5e-05 24.1 6.2 0.058 13.8 0.1 4.3 4 0 0 4 4 4 2 HEAT repeats Xpo1 PF08389.12 OAJ18747.1 - 7e-05 22.9 0.0 0.003 17.6 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 OAJ18747.1 - 0.00059 19.9 0.1 0.21 11.9 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ18747.1 - 0.003 18.1 0.0 0.35 11.5 0.0 3.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 OAJ18747.1 - 0.0052 15.9 0.4 0.12 11.5 0.4 2.8 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HTH_psq PF05225.16 OAJ18747.1 - 0.017 14.8 0.4 0.043 13.6 0.4 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain XPC-binding PF09280.11 OAJ18747.1 - 0.044 13.5 0.4 0.21 11.4 0.1 2.4 2 0 0 2 2 2 0 XPC-binding domain HEAT_EZ PF13513.6 OAJ18747.1 - 1 10.0 5.6 1.3 9.6 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat Scs3p PF10261.9 OAJ18748.1 - 8.9e-49 166.2 0.0 1.9e-48 165.2 0.0 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YsaB PF13983.6 OAJ18748.1 - 0.23 11.8 0.0 1.4 9.2 0.0 2.0 1 1 0 1 1 1 0 YsaB-like lipoprotein RRM_1 PF00076.22 OAJ18749.1 - 2.2e-34 117.1 0.0 7.6e-17 60.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 OAJ18749.1 - 0.0077 16.3 0.3 0.0077 16.3 0.3 2.3 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit RSN1_7TM PF02714.15 OAJ18751.1 - 4.7e-31 108.1 19.7 6.5e-31 107.7 19.7 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ18751.1 - 6.1e-16 59.2 0.1 2.5e-10 40.9 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ18751.1 - 3.6e-13 49.5 3.2 3.6e-13 49.5 3.2 3.5 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport AOX PF01786.17 OAJ18752.1 - 9.8e-91 303.1 0.1 1.2e-90 302.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF938 PF06080.12 OAJ18753.1 - 4.5e-31 108.2 0.0 7.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 OAJ18753.1 - 0.042 14.6 0.3 0.42 11.4 0.3 2.4 1 1 0 1 1 1 0 Methyltransferase domain TFIIS_M PF07500.14 OAJ18768.1 - 6.9e-24 84.5 0.6 6.9e-24 84.5 0.6 2.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAJ18768.1 - 3.6e-18 65.1 7.2 5.7e-18 64.5 7.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAJ18768.1 - 5.7e-13 48.7 0.9 1.4e-12 47.4 0.9 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 OAJ18768.1 - 0.33 10.9 2.1 0.76 9.8 2.1 1.5 1 0 0 1 1 1 0 DNL zinc finger AMP-binding PF00501.28 OAJ18769.1 - 1.7e-80 270.7 0.0 2.2e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ18769.1 - 5.2e-13 49.8 0.0 1.5e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSase_L_D2 PF02786.17 OAJ18769.1 - 0.17 11.4 0.0 3.1 7.2 0.0 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Cpn10 PF00166.21 OAJ18770.1 - 2.4e-26 91.6 0.0 2.7e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 OAJ18771.1 - 5.7e-85 285.8 8.1 1e-84 284.9 8.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DEAD PF00270.29 OAJ18772.1 - 7.2e-45 152.9 0.0 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ18772.1 - 2.3e-24 85.9 0.0 1.7e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ18772.1 - 8.1e-18 64.4 0.1 1.5e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OAJ18772.1 - 0.00019 20.7 0.0 0.00033 19.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OAJ18772.1 - 0.0043 17.1 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tombus_movement PF05318.12 OAJ18772.1 - 0.39 11.6 5.2 0.71 10.7 3.3 2.6 2 0 0 2 2 2 0 Tombusvirus movement protein RRM_1 PF00076.22 OAJ18773.1 - 5e-10 39.1 0.1 1.2e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ18773.1 - 0.0077 15.8 0.0 0.0088 15.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PLA2_B PF01735.18 OAJ18774.1 - 3.8e-13 48.7 0.0 2.2e-06 26.4 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain DUF2742 PF10888.8 OAJ18774.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) Bromodomain PF00439.25 OAJ18775.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Pkinase PF00069.25 OAJ18777.1 - 2.7e-72 243.3 0.0 3.5e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18777.1 - 6.8e-36 123.9 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAJ18777.1 - 1e-18 67.9 0.0 1.2e-16 61.2 0.0 2.9 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 OAJ18777.1 - 2.1e-06 27.2 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 OAJ18777.1 - 0.00021 21.4 0.1 0.00046 20.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 OAJ18777.1 - 0.011 15.3 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OAJ18777.1 - 0.13 11.2 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Syja_N PF02383.18 OAJ18778.1 - 6.9e-78 262.2 0.0 1e-77 261.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain FHA PF00498.26 OAJ18780.1 - 3.9e-08 33.5 0.1 1.3e-07 31.8 0.1 1.9 1 1 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.9 OAJ18781.1 - 9.2e-56 188.8 0.0 3.3e-55 187.0 0.0 2.0 2 1 0 2 2 2 1 Gti1/Pac2 family Na_Ca_ex PF01699.24 OAJ18782.1 - 5e-38 130.4 28.3 2e-20 73.3 10.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein BTB_2 PF02214.22 OAJ18783.1 - 0.1 13.0 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain TFIIE-A_C PF11521.8 OAJ18783.1 - 0.59 10.5 4.7 7.1 7.0 0.1 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha CENP-B_dimeris PF09026.10 OAJ18783.1 - 1.9 8.9 7.1 6.7 7.2 3.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 OAJ18783.1 - 3.5 5.6 5.1 0.2 9.7 0.1 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen AMP-binding PF00501.28 OAJ18784.1 - 5.4e-83 278.9 0.0 6.6e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme CPSase_L_D2 PF02786.17 OAJ18784.1 - 0.048 13.2 0.1 0.71 9.3 0.0 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain FA_hydroxylase PF04116.13 OAJ18785.1 - 4.6e-20 72.3 14.2 8.9e-20 71.4 10.4 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Pil1 PF13805.6 OAJ18786.1 - 8.8e-14 51.6 1.0 2e-13 50.5 1.0 1.6 1 0 0 1 1 1 1 Eisosome component PIL1 AMP-binding PF00501.28 OAJ18787.1 - 4.7e-80 269.2 0.0 5.9e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ18787.1 - 2.3e-10 41.3 0.0 8e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_6 PF13458.6 OAJ18787.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein zf-AN1 PF01428.16 OAJ18788.1 - 2.9e-16 59.3 34.6 6.1e-08 32.7 12.5 2.6 2 0 0 2 2 2 2 AN1-like Zinc finger SOG2 PF10428.9 OAJ18788.1 - 1.9 7.6 8.2 0.73 9.0 3.0 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein DUF2087 PF09860.9 OAJ18789.1 - 0.05 13.8 0.4 0.089 13.0 0.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Sdh5 PF03937.16 OAJ18806.1 - 2.8e-24 84.9 0.5 1.2e-23 82.8 0.3 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DUF1674 PF07896.12 OAJ18806.1 - 0.0024 18.3 0.4 0.0095 16.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Drf_FH1 PF06346.12 OAJ18807.1 - 0.0011 18.7 21.3 0.0011 18.7 21.3 3.4 2 2 1 4 4 4 2 Formin Homology Region 1 DUF3759 PF12585.8 OAJ18808.1 - 0.01 15.8 1.0 0.014 15.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) dCMP_cyt_deam_1 PF00383.23 OAJ18809.1 - 1.6e-21 76.1 0.0 2.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ18809.1 - 1.3e-18 67.0 0.0 1e-09 38.3 0.0 2.0 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 OAJ18809.1 - 3.7e-07 30.3 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 OAJ18809.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 SMC_Nse1 PF07574.13 OAJ18810.1 - 1.3e-24 87.2 4.0 2.3e-23 83.1 0.1 2.6 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex Myc_N PF01056.18 OAJ18810.1 - 3.4e-05 23.9 5.5 4.9e-05 23.4 5.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region zf-RING-like PF08746.11 OAJ18810.1 - 5.7e-05 23.3 5.7 9.5e-05 22.6 5.7 1.4 1 0 0 1 1 1 1 RING-like domain Pox_Ag35 PF03286.14 OAJ18810.1 - 0.052 13.3 10.2 0.1 12.4 10.2 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rubredoxin_2 PF18073.1 OAJ18810.1 - 0.073 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain Nucleo_P87 PF07267.11 OAJ18810.1 - 0.086 11.7 1.8 0.11 11.4 1.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-HC5HC2H PF13771.6 OAJ18810.1 - 0.41 10.9 3.0 0.97 9.7 3.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CDC27 PF09507.10 OAJ18810.1 - 0.55 9.6 16.6 0.78 9.1 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 OAJ18810.1 - 0.7 8.6 2.7 0.73 8.6 2.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PBP1_TM PF14812.6 OAJ18810.1 - 0.93 9.9 21.3 0.062 13.7 10.0 2.8 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RR_TM4-6 PF06459.12 OAJ18810.1 - 1.1 9.0 11.9 1.7 8.4 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.6 OAJ18810.1 - 2 8.0 7.7 3.7 7.1 7.7 1.8 1 1 0 1 1 1 0 Putative metallopeptidase domain ORC6 PF05460.13 OAJ18810.1 - 2 7.6 9.0 3 7.0 9.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PAC1 PF16094.5 OAJ18810.1 - 2.4 7.3 6.8 4.4 6.4 6.8 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 SURF2 PF05477.11 OAJ18810.1 - 3.1 7.4 12.8 4.6 6.9 12.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 OAJ18810.1 - 3.4 5.7 8.0 4.5 5.2 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ18810.1 - 3.5 6.9 16.7 6.8 5.9 16.7 1.5 1 1 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 OAJ18810.1 - 3.7 6.9 9.6 5.5 6.3 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Hid1 PF12722.7 OAJ18810.1 - 5.7 4.9 7.9 7.6 4.5 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FANCL_C PF11793.8 OAJ18810.1 - 5.8 7.2 6.0 25 5.2 5.4 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain WD40 PF00400.32 OAJ18811.1 - 1.3e-24 85.9 12.2 0.0002 22.1 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18811.1 - 0.0022 18.2 0.0 10 6.5 0.0 4.7 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 OAJ18812.1 - 3.6e-35 120.7 0.0 5.7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor Abhydrolase_1 PF00561.20 OAJ18813.1 - 8.5e-25 87.9 0.1 4.8e-21 75.6 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ18813.1 - 7.3e-11 42.1 0.0 1.5e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAJ18813.1 - 0.052 12.8 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pterin_4a PF01329.19 OAJ18814.1 - 6.1e-25 87.2 0.1 8e-25 86.8 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase UPF0086 PF01868.16 OAJ18815.1 - 1.5e-16 60.1 0.0 4.4e-16 58.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function UPF0086 Cyclin PF08613.11 OAJ18816.1 - 1.2e-06 29.0 0.0 3.6e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Cyclin GIY-YIG PF01541.24 OAJ18817.1 - 6.1e-10 39.2 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain E7 PF00527.18 OAJ18817.1 - 3.6 7.8 5.3 0.39 11.0 0.3 2.0 2 0 0 2 2 2 0 E7 protein, Early protein 4HBT_3 PF13622.6 OAJ18818.1 - 7e-31 108.4 0.9 9.7e-31 107.9 0.9 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ18818.1 - 1.9e-06 27.8 0.0 6.7e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase 4HBT PF03061.22 OAJ18818.1 - 0.0038 17.5 0.1 0.22 11.9 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily SLD5_C PF16922.5 OAJ18819.1 - 7.9e-14 51.6 0.0 1.6e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAJ18819.1 - 7.7e-06 26.3 0.1 1.3e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein TFIIF_alpha PF05793.12 OAJ18819.1 - 1.1 7.8 2.3 1.4 7.4 2.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1604 PF07713.13 OAJ18821.1 - 1.9e-36 123.7 4.2 1.9e-36 123.7 4.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAJ18821.1 - 0.00019 21.2 1.1 0.00048 20.0 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ18821.1 - 0.0065 16.5 0.0 0.0065 16.5 0.0 2.7 3 0 0 3 3 3 1 G-patch domain GPI-anchored PF10342.9 OAJ18822.1 - 1.2e-06 29.1 0.0 5.9e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PP2C PF00481.21 OAJ18824.1 - 6.4e-33 114.5 0.0 1.8e-30 106.4 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C DDE_Tnp_4 PF13359.6 OAJ18826.1 - 2.8e-34 118.1 0.0 4.6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ18826.1 - 4.3e-08 33.0 0.0 7.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ18826.1 - 1.1e-07 31.7 0.0 1.2e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Plant transposon protein HTH_Tnp_4 PF13613.6 OAJ18826.1 - 0.0002 21.0 0.1 0.00046 19.9 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.6 OAJ18826.1 - 0.0027 17.8 0.0 0.033 14.3 0.0 2.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 OAJ18826.1 - 0.013 15.3 0.2 0.16 11.8 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 OAJ18826.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 VHP PF02209.19 OAJ18826.1 - 0.18 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Villin headpiece domain HTH_36 PF13730.6 OAJ18826.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain XAP5 PF04921.14 OAJ18828.1 - 1.4e-88 297.0 7.1 1.4e-88 297.0 7.1 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator Ndc1_Nup PF09531.10 OAJ18828.1 - 7.8 5.1 6.2 9.5 4.8 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mannosyl_trans3 PF11051.8 OAJ18829.1 - 4.3e-07 29.6 0.0 5.3e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Mannosyltransferase putative Methyltr_RsmB-F PF01189.17 OAJ18830.1 - 1.1e-71 240.6 0.0 1.6e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAJ18830.1 - 4.7e-09 36.6 0.0 9.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAJ18830.1 - 0.0012 19.0 0.0 0.0079 16.3 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 OAJ18830.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 OAJ18830.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAJ18830.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ18830.1 - 0.042 14.5 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 OAJ18830.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) ASFV_J13L PF05568.11 OAJ18830.1 - 5.6 6.7 17.0 13 5.5 17.0 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein Radical_SAM_C PF16199.5 OAJ18831.1 - 2e-31 107.8 0.0 4.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAJ18831.1 - 2.9e-18 66.8 0.4 2.4e-17 63.8 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAJ18831.1 - 1.1e-07 32.1 0.1 2.5e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ18831.1 - 7.5e-06 25.9 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ18831.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein zf-SNAP50_C PF12251.8 OAJ18832.1 - 2.7e-08 33.7 0.0 6.8e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal SKN1 PF03935.15 OAJ18850.1 - 9.3e-178 591.7 1.4 1.2e-177 591.4 1.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4112 PF13430.6 OAJ18851.1 - 3.2e-31 107.7 0.1 4.3e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) BAR_2 PF10455.9 OAJ18852.1 - 2.1e-43 148.5 0.0 3.8e-43 147.7 0.0 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAJ18852.1 - 1.9e-11 44.1 1.7 1.1e-08 35.0 0.4 2.1 2 0 0 2 2 2 2 BAR domain Seryl_tRNA_N PF02403.22 OAJ18852.1 - 2.2 8.5 7.9 2.8 8.2 0.0 3.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.12 OAJ18852.1 - 3.4 7.8 9.8 0.2 11.8 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) HSCB_C PF07743.13 OAJ18852.1 - 5.2 7.6 6.3 52 4.4 2.9 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain UBX PF00789.20 OAJ18853.1 - 3.9e-09 36.6 0.0 1.5e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 OAJ18853.1 - 1.5e-05 24.8 0.1 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain XPA_N PF01286.18 OAJ18853.1 - 0.087 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 XPA protein N-terminal zf-C2H2 PF00096.26 OAJ18853.1 - 0.097 13.2 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 OAJ18853.1 - 0.11 12.8 0.5 0.11 12.8 0.5 1.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 OAJ18853.1 - 0.2 11.6 0.4 0.52 10.3 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Hamartin PF04388.12 OAJ18853.1 - 2.5 6.6 9.3 3.1 6.3 9.3 1.0 1 0 0 1 1 1 0 Hamartin protein Rtf2 PF04641.12 OAJ18853.1 - 3.4 6.9 21.3 5.3 6.3 21.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.12 OAJ18853.1 - 8 6.2 20.1 12 5.7 20.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.27 OAJ18854.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 OAJ18855.1 - 0.009 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family adh_short PF00106.25 OAJ18856.1 - 8.6e-31 106.9 0.0 9.1e-24 84.0 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ18856.1 - 2.6e-26 92.6 0.0 8.4e-22 77.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ18856.1 - 7.9e-05 22.6 2.8 0.0041 17.0 2.8 2.8 1 1 0 1 1 1 1 KR domain RskA PF10099.9 OAJ18857.1 - 0.00045 20.6 16.9 0.00045 20.6 16.9 1.7 2 0 0 2 2 2 1 Anti-sigma-K factor rskA MEDS PF14417.6 OAJ18857.1 - 0.045 13.6 0.3 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF2868 PF11067.8 OAJ18857.1 - 0.073 12.6 8.5 1.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) E1-E2_ATPase PF00122.20 OAJ18858.1 - 2.3e-35 121.8 6.7 4e-29 101.4 0.0 4.0 4 1 1 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ18858.1 - 8.5e-27 94.0 4.7 8.5e-27 94.0 4.7 3.2 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ18858.1 - 8.7e-21 75.2 0.0 3.7e-19 69.9 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ18858.1 - 2.3e-19 69.2 0.0 4.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ18858.1 - 1.7e-14 53.3 0.0 1.7e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ18858.1 - 1.5e-06 28.1 0.3 1.6e-05 24.8 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP19 PF01922.17 OAJ18858.1 - 0.036 15.0 0.0 0.22 12.5 0.0 2.3 2 0 0 2 2 2 0 SRP19 protein Tyr_Deacylase PF02580.16 OAJ18859.1 - 9e-53 178.7 0.0 1.1e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DnaJ PF00226.31 OAJ18860.1 - 5.9e-17 61.6 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Rav1p_C PF12234.8 OAJ18861.1 - 8.8e-100 335.0 0.0 1.7e-99 334.0 0.0 1.4 1 0 0 1 1 1 1 RAVE protein 1 C terminal Pro_CA PF00484.19 OAJ18862.1 - 1.6e-11 44.7 0.0 2.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Lipase_3 PF01764.25 OAJ18864.1 - 1.4e-23 83.3 0.0 2.2e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ18864.1 - 0.0041 17.7 2.8 0.008 16.8 0.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.11 OAJ18864.1 - 0.012 15.2 0.1 0.042 13.4 0.0 1.9 2 0 0 2 2 2 0 PE-PPE domain Hydrolase_4 PF12146.8 OAJ18864.1 - 0.014 14.6 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 OAJ18864.1 - 0.16 11.5 0.2 1.3 8.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2756 PF10956.8 OAJ18864.1 - 0.18 12.3 0.2 0.36 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Metallophos PF00149.28 OAJ18865.1 - 3.8e-13 50.4 0.4 5.6e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Oxidored_FMN PF00724.20 OAJ18866.1 - 3.6e-48 164.6 0.0 5.1e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_N PF08240.12 OAJ18867.1 - 4e-21 74.9 1.8 8.7e-21 73.9 1.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ18867.1 - 4.9e-14 52.4 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ18867.1 - 3.4e-05 23.3 0.1 7e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ18867.1 - 0.00076 19.5 0.0 0.0025 17.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAJ18867.1 - 0.0013 18.0 0.3 0.0027 17.0 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAJ18867.1 - 0.003 17.5 0.1 0.0052 16.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAJ18867.1 - 0.0077 16.4 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 OAJ18867.1 - 0.057 14.2 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold XdhC_C PF13478.6 OAJ18867.1 - 0.064 13.8 0.0 0.35 11.4 0.0 2.1 2 1 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 OAJ18867.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 OAJ18867.1 - 0.34 10.2 1.4 0.58 9.5 1.4 1.3 1 0 0 1 1 1 0 ThiF family MoCF_biosynth PF00994.24 OAJ18869.1 - 1.1e-51 174.3 0.7 6.5e-26 90.7 0.1 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAJ18869.1 - 1.4e-30 106.2 1.9 2.9e-30 105.1 1.9 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 OAJ18869.1 - 2.6e-15 56.4 0.1 7.3e-15 54.9 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DUF2034 PF10356.9 OAJ18870.1 - 1.5e-09 37.5 0.3 4.6e-07 29.5 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAJ18870.1 - 0.0013 18.8 0.0 0.0037 17.3 0.0 1.9 1 1 1 2 2 2 1 Restriction endonuclease SRP54 PF00448.22 OAJ18871.1 - 2e-45 154.9 0.0 2.4e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 OAJ18871.1 - 3.3e-45 155.2 0.0 6.1e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 OAJ18871.1 - 6.2e-07 29.5 0.0 2.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAJ18871.1 - 0.0007 18.6 0.1 0.15 11.1 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 OAJ18871.1 - 0.0075 16.3 0.0 0.046 13.8 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF4653 PF15546.6 OAJ18871.1 - 0.067 12.8 2.9 0.054 13.1 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Fer4_NifH PF00142.18 OAJ18871.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 OAJ18871.1 - 0.076 13.4 3.0 0.54 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 OAJ18871.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAJ18871.1 - 0.12 12.3 0.0 0.67 9.8 0.0 2.2 1 1 0 1 1 1 0 NTPase Iso_dh PF00180.20 OAJ18872.1 - 6.4e-115 384.0 0.0 7.3e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.12 OAJ18872.1 - 0.058 13.2 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 YebG protein SKI PF01202.22 OAJ18873.1 - 3.6e-08 33.7 0.8 2.3e-05 24.6 0.0 3.3 1 1 2 3 3 3 1 Shikimate kinase AAA_18 PF13238.6 OAJ18873.1 - 4.5e-07 30.5 1.0 7.3e-05 23.3 0.9 3.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ18873.1 - 3e-05 24.2 0.1 0.00085 19.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 OAJ18873.1 - 0.0042 17.3 1.2 0.012 15.8 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAJ18873.1 - 0.0045 17.0 0.1 0.39 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ18873.1 - 0.0045 17.4 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 OAJ18873.1 - 0.014 15.3 0.4 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 OAJ18873.1 - 0.018 14.9 0.6 0.85 9.5 0.0 2.3 1 1 0 2 2 2 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 OAJ18873.1 - 0.034 14.0 0.1 0.064 13.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Cytidylate_kin2 PF13189.6 OAJ18873.1 - 0.04 14.1 0.1 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_22 PF13401.6 OAJ18873.1 - 0.047 14.0 0.0 0.11 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 OAJ18873.1 - 0.048 13.4 2.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 0 Cytidylate kinase Hydin_ADK PF17213.3 OAJ18873.1 - 0.15 12.3 1.8 17 5.6 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_25 PF13481.6 OAJ18873.1 - 0.18 11.4 2.8 0.25 10.9 1.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ18873.1 - 0.2 11.4 0.7 0.39 10.5 0.7 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC45 PF02724.14 OAJ18873.1 - 0.23 9.7 5.4 0.28 9.4 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 OAJ18873.1 - 0.25 11.8 3.5 0.74 10.3 3.5 1.9 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 OAJ18873.1 - 0.6 10.5 5.5 6.5 7.2 0.0 3.4 3 1 1 4 4 4 0 AAA domain CGI-121 PF08617.10 OAJ18874.1 - 2.9e-35 121.8 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Peptidase_S28 PF05577.12 OAJ18875.1 - 2.9e-38 131.8 0.9 8.9e-34 117.0 0.0 2.8 2 1 0 3 3 3 2 Serine carboxypeptidase S28 Rnk_N PF14760.6 OAJ18875.1 - 0.12 12.9 0.4 0.38 11.3 0.4 1.8 1 0 0 1 1 1 0 Rnk N-terminus Dak1 PF02733.17 OAJ18876.1 - 3.4e-84 282.4 0.0 4.5e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAJ18876.1 - 3.9e-35 121.3 5.0 9.2e-35 120.1 5.0 1.6 1 1 0 1 1 1 1 DAK2 domain GPI-anchored PF10342.9 OAJ18877.1 - 1.3e-09 38.7 1.3 1.5e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_5_C PF18564.1 OAJ18878.1 - 0.09 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain SKN1 PF03935.15 OAJ18879.1 - 1.6e-179 597.5 1.4 2.1e-179 597.1 1.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OAJ18879.1 - 0.0036 16.8 0.2 0.54 9.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 MOSC PF03473.17 OAJ18897.1 - 0.0088 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 MOSC domain DcpS_C PF11969.8 OAJ18898.1 - 2e-20 73.4 0.1 4.5e-20 72.2 0.1 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ18898.1 - 2.2e-09 37.9 1.3 6.3e-09 36.5 1.3 1.7 1 1 0 1 1 1 1 HIT domain DUF2623 PF11115.8 OAJ18898.1 - 0.0035 17.4 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2623) CwfJ_C_1 PF04677.15 OAJ18898.1 - 0.041 13.7 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 DHHC PF01529.20 OAJ18899.1 - 1.4e-33 115.9 4.2 3e-33 114.8 4.2 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase SR-25 PF10500.9 OAJ18899.1 - 0.007 16.0 18.9 0.016 14.9 18.9 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OAJ18899.1 - 0.71 8.4 4.5 1.1 7.7 4.5 1.3 1 0 0 1 1 1 0 Macoilin family Chorion_2 PF03964.15 OAJ18899.1 - 1.5 9.7 14.8 7.3 7.5 8.6 2.8 2 0 0 2 2 2 0 Chorion family 2 DUF755 PF05501.11 OAJ18899.1 - 5.5 7.3 18.7 15 5.9 18.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) MOSC_N PF03476.16 OAJ18900.1 - 9e-18 64.3 0.0 1.9e-17 63.3 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ18900.1 - 4.9e-07 29.8 0.1 1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 MOSC domain DUF4247 PF14042.6 OAJ18900.1 - 0.097 13.4 0.4 1.1e+02 3.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4247) zinc_ribbon_9 PF14369.6 OAJ18901.1 - 6.8e-08 32.6 0.5 1.3e-07 31.7 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon HypA PF01155.19 OAJ18901.1 - 0.0034 17.4 0.1 0.0045 17.0 0.1 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 OAJ18901.1 - 0.0058 16.0 0.7 2.9 7.4 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain Zn-ribbon_8 PF09723.10 OAJ18901.1 - 0.0086 16.2 0.5 0.016 15.3 0.5 1.5 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 OAJ18901.1 - 0.088 12.8 0.8 0.2 11.7 0.8 1.6 1 1 0 1 1 1 0 Double zinc ribbon CDH-cyt PF16010.5 OAJ18902.1 - 3.3e-11 43.2 1.8 1.1e-10 41.5 2.3 1.6 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ18902.1 - 5.5e-09 36.3 8.9 1.1e-08 35.4 8.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ18902.1 - 2.2e-05 24.6 0.1 4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 OAJ18902.1 - 2.7 7.8 9.1 1.3 8.9 5.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) ABC_tran PF00005.27 OAJ18903.1 - 2e-51 174.1 0.0 2.3e-26 93.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ18903.1 - 1.4e-47 162.6 10.3 9.5e-27 94.3 0.9 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ18903.1 - 6.1e-12 45.4 0.3 9.8e-05 21.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ18903.1 - 1.2e-06 28.6 0.1 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 OAJ18903.1 - 7.1e-06 25.7 0.2 0.077 12.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ18903.1 - 2.9e-05 24.1 0.0 0.22 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ18903.1 - 0.00012 22.1 0.8 0.31 11.1 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 OAJ18903.1 - 0.00016 22.0 0.1 1 9.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 OAJ18903.1 - 0.00027 21.5 0.0 0.037 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ18903.1 - 0.00041 20.0 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 OAJ18903.1 - 0.00053 20.2 0.3 0.26 11.3 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 OAJ18903.1 - 0.00063 20.2 3.5 1.1 9.6 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain Zeta_toxin PF06414.12 OAJ18903.1 - 0.00068 19.0 0.2 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 OAJ18903.1 - 0.002 18.0 0.4 1.6 8.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 OAJ18903.1 - 0.0021 17.3 0.2 1.3 8.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 OAJ18903.1 - 0.0072 16.1 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 OAJ18903.1 - 0.0083 15.7 0.2 3 7.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 OAJ18903.1 - 0.011 15.1 0.1 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 OAJ18903.1 - 0.012 14.7 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 OAJ18903.1 - 0.013 15.7 0.2 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 OAJ18903.1 - 0.017 14.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 OAJ18903.1 - 0.032 14.8 0.0 1.9 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ18903.1 - 0.072 13.2 1.7 7.5 6.7 0.2 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ18903.1 - 0.072 13.5 0.1 9.9 6.6 0.0 3.0 3 0 0 3 3 2 0 RNA helicase BCA_ABC_TP_C PF12399.8 OAJ18903.1 - 0.081 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter TsaE PF02367.17 OAJ18903.1 - 0.1 12.6 0.0 34 4.4 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma_M_inh PF17453.2 OAJ18903.1 - 2.1 8.8 6.3 23 5.5 0.1 3.3 3 0 0 3 3 2 0 Sigma-M inhibitor WD40 PF00400.32 OAJ18904.1 - 9.7e-20 70.5 3.0 0.00036 21.3 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18904.1 - 3.2e-09 37.0 0.0 3.7e-05 23.9 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ18904.1 - 5.1e-06 26.5 0.0 0.0037 17.2 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAJ18904.1 - 0.057 12.7 0.0 0.45 9.8 0.0 2.3 3 0 0 3 3 3 0 WD40-like domain MetallophosC PF16370.5 OAJ18904.1 - 0.071 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Ge1_WD40 PF16529.5 OAJ18904.1 - 0.11 11.4 0.0 17 4.2 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tannase PF07519.11 OAJ18906.1 - 8.6e-62 209.6 0.1 2.6e-61 208.0 0.1 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase FSA_C PF10479.9 OAJ18906.1 - 0.73 7.9 7.5 1.1 7.3 7.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 OAJ18906.1 - 4.4 5.4 13.1 6.7 4.8 13.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.22 OAJ18907.1 - 4.6e-36 123.9 0.0 5.2e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ18907.1 - 4e-09 36.7 0.0 6.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAJ18907.1 - 0.0059 16.2 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OAJ18907.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.18 OAJ18907.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Mob1_phocein PF03637.17 OAJ18908.1 - 7.8e-77 257.0 0.1 9.2e-77 256.8 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Tannase PF07519.11 OAJ18909.1 - 3.3e-61 207.6 0.1 1.3e-60 205.7 0.1 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase RRM_1 PF00076.22 OAJ18910.1 - 4.4e-28 96.9 0.8 2.5e-08 33.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ18910.1 - 0.00017 21.4 0.0 9.9 6.1 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif DUF4523 PF15023.6 OAJ18910.1 - 0.0013 18.6 0.0 5.7 6.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 OAJ18910.1 - 0.019 15.1 0.0 2.5 8.3 0.0 3.3 4 0 0 4 4 4 0 RNA recognition motif RRM_3 PF08777.11 OAJ18910.1 - 0.03 14.4 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Pyridoxal_deC PF00282.19 OAJ18911.1 - 1.7e-73 247.6 0.0 2.1e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAJ18911.1 - 0.004 16.5 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L13 PF00572.18 OAJ18912.1 - 5e-54 181.9 0.8 6.4e-54 181.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Sipho_Gp37 PF14594.6 OAJ18912.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein SNARE_assoc PF09335.11 OAJ18914.1 - 1.5e-14 54.5 7.6 3.8e-13 50.0 5.0 2.9 2 1 0 2 2 2 2 SNARE associated Golgi protein HemY_N PF07219.13 OAJ18914.1 - 1.1 9.5 4.4 15 5.8 0.1 3.7 3 0 0 3 3 3 0 HemY protein N-terminus DUF5437 PF17505.2 OAJ18916.1 - 0.052 13.6 4.5 0.28 11.2 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5437) Toxin_29 PF08116.11 OAJ18917.1 - 0.31 11.1 0.0 0.31 11.1 0.0 5.8 5 1 1 6 6 6 0 PhTx neurotoxin family UPF0506 PF11703.8 OAJ18917.1 - 2.3 8.6 43.6 4.1 7.8 9.2 4.6 2 2 2 4 4 4 0 UPF0506 EB PF01683.18 OAJ18917.1 - 8.7 6.7 50.0 5.1 7.5 7.0 6.1 2 2 4 6 6 6 0 EB module Adeno_E3_CR2 PF02439.15 OAJ18918.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SH3_9 PF14604.6 OAJ18919.1 - 2e-22 78.8 1.4 3.9e-14 52.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAJ18919.1 - 5.8e-21 73.8 0.0 6.1e-10 38.6 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OAJ18919.1 - 5.7e-15 54.7 0.1 1.3e-08 34.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 OAJ18919.1 - 8.1e-14 51.7 0.0 4.8e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 OAJ18919.1 - 5.8e-12 45.3 4.3 1.1e-11 44.4 4.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 OAJ18919.1 - 0.0011 19.2 0.9 0.0026 18.0 0.2 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain RhoGEF PF00621.20 OAJ18919.1 - 0.0015 18.8 0.8 0.0036 17.6 0.8 1.7 1 1 0 1 1 1 1 RhoGEF domain Prominin PF05478.11 OAJ18919.1 - 0.11 10.4 1.7 0.14 10.1 0.5 1.6 1 1 0 1 1 1 0 Prominin CENP-Q PF13094.6 OAJ18919.1 - 1.4 9.1 16.6 3.6 7.8 0.1 3.5 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit CDH-cyt PF16010.5 OAJ18920.1 - 3.3e-10 39.9 1.1 6.9e-10 38.9 1.1 1.5 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ18920.1 - 8.7e-10 38.9 6.6 1.4e-09 38.2 6.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ18920.1 - 0.00036 20.7 0.1 0.00062 20.0 0.1 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 OAJ18920.1 - 0.015 15.0 3.5 0.015 15.0 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 OAJ18920.1 - 1.7 8.8 7.3 3.5 7.8 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Tub_N PF16322.5 OAJ18921.1 - 0.0077 16.7 5.5 0.0077 16.7 5.5 4.5 4 1 1 5 5 5 1 Tubby N-terminal PBP1_TM PF14812.6 OAJ18921.1 - 0.32 11.4 8.8 1.2 9.6 8.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 OAJ18921.1 - 2 8.4 9.5 0.37 10.8 5.3 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 OAJ18921.1 - 7 5.9 10.2 17 4.6 10.2 1.6 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 OAJ18933.1 - 2.4e-10 40.5 0.0 2.4e-10 40.5 0.0 2.6 3 0 0 3 3 3 1 PPP4R2 TFIIA PF03153.13 OAJ18933.1 - 1.9 8.4 29.1 0.038 14.0 5.7 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L2_C PF03947.18 OAJ18934.1 - 1.2e-45 154.8 2.6 2.3e-45 153.9 2.6 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAJ18934.1 - 1.2e-14 54.0 0.1 2.7e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Pal1 PF08316.11 OAJ18936.1 - 1.5e-14 55.0 3.5 1.5e-14 54.9 1.2 2.2 1 1 1 2 2 2 1 Pal1 cell morphology protein Imm_superinfect PF14373.6 OAJ18937.1 - 0.081 12.9 1.8 8.2 6.4 0.1 2.8 2 1 0 2 2 2 0 Superinfection immunity protein ATG_C PF09333.11 OAJ18938.1 - 0.025 14.9 10.2 0.7 10.3 0.2 5.5 3 2 3 6 6 6 0 Autophagy-related protein C terminal domain Fzo_mitofusin PF04799.13 OAJ18938.1 - 0.069 12.7 5.4 0.28 10.7 0.2 3.1 2 2 1 3 3 3 0 fzo-like conserved region BST2 PF16716.5 OAJ18938.1 - 0.089 13.4 0.0 0.089 13.4 0.0 5.3 3 2 3 6 6 6 0 Bone marrow stromal antigen 2 V-SNARE_C PF12352.8 OAJ18938.1 - 0.096 13.0 9.7 0.16 12.3 1.7 4.0 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus DUF2681 PF10883.8 OAJ18938.1 - 0.44 11.0 7.7 0.49 10.8 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) COG2 PF06148.11 OAJ18938.1 - 1 9.5 13.4 0.57 10.3 1.8 4.4 2 2 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cep57_MT_bd PF06657.13 OAJ18938.1 - 1 9.8 7.8 1.6 9.2 0.1 3.8 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 V_ATPase_I PF01496.19 OAJ18938.1 - 2.6 5.9 11.5 2.3 6.0 7.1 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 OAJ18938.1 - 3.5 7.7 16.8 4.3 7.4 0.3 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 OAJ18938.1 - 5 7.3 30.1 3 8.0 0.1 4.6 3 2 1 4 4 4 0 BRE1 E3 ubiquitin ligase Med9 PF07544.13 OAJ18938.1 - 9.8 6.4 10.6 10 6.3 1.0 3.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UPRTase PF14681.6 OAJ18942.1 - 5.4e-79 264.4 0.0 6.3e-79 264.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAJ18942.1 - 0.00011 21.7 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MSP1_C PF07462.11 OAJ18943.1 - 4.3 5.9 8.4 7.3 5.2 8.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus EXS PF03124.14 OAJ18944.1 - 1.2e-73 248.4 11.8 1.6e-62 211.7 9.2 2.2 2 0 0 2 2 2 2 EXS family Frag1 PF10277.9 OAJ18945.1 - 8.8e-38 130.0 17.7 1e-37 129.8 17.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Virul_fac_BrkB PF03631.15 OAJ18945.1 - 6.7e-05 22.6 6.9 9.6e-05 22.1 6.9 1.2 1 0 0 1 1 1 1 Virulence factor BrkB DUF4271 PF14093.6 OAJ18945.1 - 0.0012 18.8 2.4 0.0012 18.8 2.4 2.6 2 1 1 3 3 3 1 Domain of unknown function (DUF4271) DUF2663 PF10864.8 OAJ18945.1 - 0.25 11.8 5.8 1.4 9.3 0.9 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF2663) DUF1980 PF09323.10 OAJ18945.1 - 0.59 10.0 5.8 3.6 7.5 5.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) RelB_transactiv PF16181.5 OAJ18947.1 - 0.081 13.2 2.1 0.18 12.1 0.2 1.9 2 0 0 2 2 2 0 RelB transactivation domain PINIT PF14324.6 OAJ18949.1 - 1.2e-25 90.6 0.4 1.8e-25 90.0 0.4 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAJ18949.1 - 5.3e-22 77.3 3.0 9e-22 76.6 3.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAJ18949.1 - 1.1e-08 34.7 0.8 2.1e-08 33.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OAJ18949.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_2 PF13923.6 OAJ18949.1 - 0.42 10.5 2.9 0.81 9.6 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ18949.1 - 1.6 9.1 3.6 2.9 8.3 3.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF996 PF06195.13 OAJ18950.1 - 0.029 14.6 0.1 0.029 14.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Vma12 PF11712.8 OAJ18950.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.6 2 2 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Vps36_ESCRT-II PF11605.8 OAJ18951.1 - 9e-20 70.7 0.0 1.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 OAJ18951.1 - 3.2e-19 69.2 0.2 1.7e-10 40.6 0.0 2.3 1 1 1 2 2 2 2 EAP30/Vps36 family zf-RanBP PF00641.18 OAJ18951.1 - 0.0098 15.2 13.6 0.16 11.3 2.2 2.8 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others Rubredoxin PF00301.20 OAJ18951.1 - 0.028 14.4 1.4 0.092 12.8 0.0 2.4 3 0 0 3 3 3 0 Rubredoxin DZR PF12773.7 OAJ18951.1 - 0.084 12.9 6.1 0.41 10.7 0.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 OAJ18951.1 - 0.81 9.8 7.4 1.3 9.1 0.1 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 OAJ18951.1 - 1 8.8 10.4 0.19 11.2 3.7 2.8 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CS PF04969.16 OAJ18953.1 - 1.3e-18 67.7 0.3 2.4e-18 66.9 0.3 1.4 1 0 0 1 1 1 1 CS domain EMP24_GP25L PF01105.24 OAJ18953.1 - 1.1 9.1 4.2 1.4 8.8 0.9 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD CLU PF13236.6 OAJ18954.1 - 6.2e-69 232.2 0.0 2.9e-68 230.0 0.0 2.0 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAJ18954.1 - 2.9e-44 151.2 0.0 8.6e-44 149.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAJ18954.1 - 2.3e-20 72.6 8.5 1.3e-09 38.2 0.8 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ18954.1 - 9e-11 41.3 6.4 0.00068 19.4 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat CLU_N PF15044.6 OAJ18954.1 - 1.6e-05 25.2 0.0 0.00029 21.1 0.0 2.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OAJ18954.1 - 0.031 14.1 0.1 0.59 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18954.1 - 0.15 12.2 0.6 20 5.6 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18954.1 - 0.2 12.6 2.6 3.7 8.6 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat BRE1 PF08647.11 OAJ18955.1 - 0.065 13.3 4.3 0.2 11.8 4.3 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 OAJ18955.1 - 0.2 11.5 4.0 0.34 10.7 2.4 2.0 2 0 0 2 2 2 0 Septum formation initiator FlgN PF05130.12 OAJ18955.1 - 1.4 9.4 9.4 0.9 10.0 7.2 1.7 2 0 0 2 2 2 0 FlgN protein SNARE PF05739.19 OAJ18955.1 - 1.5 8.8 4.0 0.62 10.1 1.0 1.9 2 0 0 2 2 2 0 SNARE domain YscO-like PF16789.5 OAJ18955.1 - 2 8.4 9.9 0.082 12.9 3.5 1.9 2 0 0 2 2 2 0 YscO-like protein DUF4407 PF14362.6 OAJ18955.1 - 8.2 5.7 10.0 62 2.8 8.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DASH_Dad1 PF08649.10 OAJ18956.1 - 9.2e-23 80.2 0.6 1.2e-22 79.9 0.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 Apolipoprotein PF01442.18 OAJ18957.1 - 0.11 12.3 0.6 0.16 11.8 0.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CRC_subunit PF08624.10 OAJ18961.1 - 2e-39 135.1 0.0 3.1e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SMYLE_N PF18615.1 OAJ18971.1 - 2.2 7.7 7.9 2.6 7.5 7.9 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PARM PF17061.5 OAJ18971.1 - 2.5 8.2 17.7 3 7.9 17.7 1.1 1 0 0 1 1 1 0 PARM Cu_amine_oxid PF01179.20 OAJ18972.1 - 1.8e-126 422.4 0.1 2.5e-126 421.9 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 OAJ18972.1 - 1.3e-28 98.5 1.0 2.9e-28 97.4 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 OAJ18972.1 - 1.2e-07 31.8 0.0 2.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HSF_DNA-bind PF00447.17 OAJ18973.1 - 6.2e-20 71.6 0.1 1.9e-18 66.9 0.0 2.8 2 1 0 2 2 2 1 HSF-type DNA-binding SDA1 PF05285.12 OAJ18973.1 - 0.0032 17.0 0.3 0.0032 17.0 0.3 1.7 2 0 0 2 2 2 1 SDA1 Pro_isomerase PF00160.21 OAJ18974.1 - 1.3e-47 162.0 0.2 1.5e-47 161.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_G2 PF11962.8 OAJ18974.1 - 0.19 11.1 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain SAP30_Sin3_bdg PF13867.6 OAJ18975.1 - 1.9e-06 28.1 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 RskA PF10099.9 OAJ18975.1 - 0.06 13.7 15.5 0.31 11.3 2.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4179 PF13786.6 OAJ18975.1 - 0.72 10.4 4.5 17 6.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Sas10 PF09368.10 OAJ18977.1 - 1e-25 90.0 4.1 1e-25 90.0 4.1 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAJ18977.1 - 4.4e-07 30.4 1.6 1.4e-06 28.9 0.0 2.6 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fcf2 PF08698.11 OAJ18978.1 - 1.6e-18 66.8 0.0 2.5e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Tom22 PF04281.13 OAJ18981.1 - 1.4e-36 125.3 1.0 4.3e-35 120.5 1.0 2.0 1 1 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.6 OAJ18981.1 - 0.015 15.4 1.5 0.025 14.7 1.5 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective FAM176 PF14851.6 OAJ18981.1 - 0.37 10.4 1.8 1.5 8.5 1.6 2.0 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 OAJ18981.1 - 1.2 7.1 6.0 1.5 6.9 6.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi Phage_holin_2_4 PF16082.5 OAJ18981.1 - 3.1 7.6 5.1 2.2 8.1 0.2 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like NOA36 PF06524.12 OAJ18981.1 - 4.4 6.6 10.1 5.6 6.2 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAJ18981.1 - 7.1 4.7 6.3 7.9 4.5 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family SET PF00856.28 OAJ18982.1 - 2e-14 54.3 3.4 2.7e-14 53.9 0.0 3.0 3 1 0 3 3 3 1 SET domain AWS PF17907.1 OAJ18982.1 - 2.2e-10 40.4 6.8 4.2e-10 39.5 6.8 1.4 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 OAJ18983.1 - 1.2e-05 25.1 19.0 2e-05 24.4 19.0 1.4 1 0 0 1 1 1 1 PHD-finger UNC-79 PF14776.6 OAJ18983.1 - 0.48 9.1 2.6 0.79 8.4 2.6 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ribosomal_L6e PF01159.19 OAJ18984.1 - 3.7e-34 117.6 0.2 3.7e-34 117.6 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 OAJ18984.1 - 0.00089 19.5 0.3 0.00089 19.5 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Nup35_RRM PF05172.13 OAJ18985.1 - 2.9e-06 27.2 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ18985.1 - 0.00051 20.0 0.0 0.00092 19.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 OAJ18986.1 - 3.9e-68 229.7 0.0 5e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ18986.1 - 8.1e-30 104.0 0.0 1.3e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ18986.1 - 0.002 18.1 4.0 0.058 13.3 0.1 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ18986.1 - 0.05 12.5 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Choline_transpo PF04515.12 OAJ18988.1 - 1.7e-78 264.1 24.9 1.7e-78 264.1 24.9 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF1072 PF06380.11 OAJ18988.1 - 0.093 12.6 2.5 0.6 10.0 2.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) MFS_1 PF07690.16 OAJ18989.1 - 3.4e-24 85.5 34.7 6.3e-16 58.2 12.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ18989.1 - 7.2e-15 54.8 2.0 7.2e-15 54.8 2.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter NUP214 PF16755.5 OAJ18990.1 - 0.00031 20.1 0.0 0.0066 15.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 SEN1_N PF12726.7 OAJ18991.1 - 1.3e-75 255.1 5.9 8.4e-75 252.5 5.9 2.2 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAJ18991.1 - 2.7e-67 227.3 3.1 2.7e-67 227.3 3.1 2.8 3 1 0 3 3 2 1 AAA domain AAA_12 PF13087.6 OAJ18991.1 - 2e-60 203.9 0.0 3.9e-58 196.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ18991.1 - 1.2e-10 41.9 3.0 7.9e-10 39.2 1.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ18991.1 - 5.2e-10 39.4 1.1 3.3e-06 27.0 0.1 3.1 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAJ18991.1 - 5.9e-05 22.9 0.0 1.6 8.4 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAJ18991.1 - 0.0011 18.5 7.9 0.0061 16.1 7.9 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Med9 PF07544.13 OAJ18991.1 - 0.0011 19.0 3.8 0.0036 17.4 3.8 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 ResIII PF04851.15 OAJ18991.1 - 0.006 16.6 0.1 0.035 14.1 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flagellin_N PF00669.20 OAJ18991.1 - 0.024 14.8 0.5 0.024 14.8 0.5 3.6 4 0 0 4 4 2 0 Bacterial flagellin N-terminal helical region FapA PF03961.13 OAJ18991.1 - 0.031 12.9 2.0 0.05 12.2 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS6_N PF14661.6 OAJ18991.1 - 0.18 11.4 5.8 0.76 9.3 5.8 2.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_22 PF13401.6 OAJ18991.1 - 0.19 12.0 0.5 1.8 8.9 0.5 2.8 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 OAJ18991.1 - 0.27 9.1 1.1 0.47 8.3 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 OAJ18991.1 - 0.78 9.6 4.9 2.6 7.9 4.9 2.0 1 0 0 1 1 1 0 PCRF domain AAA PF00004.29 OAJ18991.1 - 2.5 8.5 7.0 8.2 6.9 3.9 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Yippee-Mis18 PF03226.14 OAJ18992.1 - 2.9e-14 53.2 0.0 5.3e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ASD2 PF08687.11 OAJ18992.1 - 0.36 10.3 0.4 1 8.9 0.0 1.7 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 IHABP4_N PF16174.5 OAJ18992.1 - 2.6 8.6 9.3 0.11 13.1 0.5 2.9 3 0 0 3 3 3 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4611 PF15387.6 OAJ18992.1 - 3.7 7.8 8.3 3.5 7.9 2.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LSM PF01423.22 OAJ18994.1 - 1.1e-17 63.4 0.0 1.8e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain Ldh_1_C PF02866.18 OAJ18995.1 - 6.9e-46 156.2 0.0 1.6e-45 155.1 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAJ18995.1 - 3.5e-44 150.3 0.1 5.2e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAJ18995.1 - 0.0012 17.9 0.0 0.0025 16.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAJ18995.1 - 0.016 15.6 0.2 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAJ18995.1 - 0.034 13.5 0.7 0.48 9.7 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RRM_1 PF00076.22 OAJ18996.1 - 1.2e-07 31.5 0.1 0.024 14.4 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 OAJ18996.1 - 0.0061 16.4 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain ANAPC15 PF15243.6 OAJ18996.1 - 0.59 10.6 0.0 0.59 10.6 0.0 6.2 3 2 1 4 4 4 0 Anaphase-promoting complex subunit 15 RtcB PF01139.17 OAJ18999.1 - 4.1e-62 210.7 0.0 5.5e-58 197.1 0.0 3.0 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB ADH_zinc_N_2 PF13602.6 OAJ19019.1 - 1.2e-08 36.1 0.0 3.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ19019.1 - 7.5e-05 22.6 0.2 0.00014 21.7 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ19019.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SAP PF02037.27 OAJ19020.1 - 3.8e-10 39.3 0.7 6.1e-10 38.6 0.7 1.3 1 0 0 1 1 1 1 SAP domain GET2 PF08690.10 OAJ19021.1 - 1.5e-12 47.8 0.0 3.3e-07 30.3 0.0 2.7 2 1 0 2 2 2 2 GET complex subunit GET2 TPT PF03151.16 OAJ19022.1 - 1.2e-23 83.9 15.4 1.6e-23 83.5 15.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ19022.1 - 1e-09 38.7 24.6 6.1e-05 23.2 8.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OAJ19022.1 - 0.0022 17.3 17.5 0.0051 16.1 16.6 1.8 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 OAJ19022.1 - 0.33 10.1 20.8 0.3 10.2 16.9 2.4 1 1 0 2 2 2 0 UAA transporter family Thiolase_N PF00108.23 OAJ19024.1 - 4.4e-92 308.1 2.6 7e-92 307.4 2.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ19024.1 - 3.3e-43 146.3 1.7 5.9e-42 142.2 0.9 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ19024.1 - 3.5e-07 30.1 3.1 1.6e-05 24.6 1.1 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ19024.1 - 2.8 7.9 9.6 2.9 7.8 0.2 3.7 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UDPG_MGDP_dh_N PF03721.14 OAJ19025.1 - 8.4e-62 208.1 0.0 1.4e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAJ19025.1 - 1.9e-34 118.2 0.1 4.1e-33 113.9 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAJ19025.1 - 1.3e-32 111.8 0.0 2.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 OAJ19025.1 - 0.0096 16.5 0.1 9.6 6.9 0.1 3.1 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OAJ19025.1 - 0.037 14.0 0.1 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 OAJ19025.1 - 0.15 12.2 0.1 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1264 PF06884.11 OAJ19026.1 - 2.6e-46 157.4 0.0 4.6e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) KRTDAP PF15200.6 OAJ19028.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Keratinocyte differentiation-associated SAC3_GANP PF03399.16 OAJ19029.1 - 7.8e-86 288.1 0.0 1.2e-85 287.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family BRCT PF00533.26 OAJ19030.1 - 4e-23 81.6 0.0 2e-07 31.3 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ19030.1 - 6.4e-21 74.1 1.8 2.8e-08 33.6 0.0 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 OAJ19030.1 - 1.3e-08 35.1 0.0 1.3 9.5 0.0 5.4 5 0 0 5 5 5 3 BRCT domain, a BRCA1 C-terminus domain TIP39 PF14980.6 OAJ19030.1 - 0.08 12.8 0.3 0.24 11.3 0.3 1.8 1 0 0 1 1 1 0 TIP39 peptide LIG3_BRCT PF16759.5 OAJ19030.1 - 0.083 13.2 0.7 15 5.9 0.0 3.3 3 1 0 3 3 3 0 DNA ligase 3 BRCT domain Methyltransf_16 PF10294.9 OAJ19031.1 - 1.1e-14 54.5 0.0 2.2e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAJ19031.1 - 0.03 13.7 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.25 OAJ19032.1 - 2.4e-18 66.3 0.1 5.9e-09 35.7 0.1 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19032.1 - 1.3e-12 47.8 0.0 1.6e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ19032.1 - 2e-05 24.6 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 KR domain ArsA_ATPase PF02374.15 OAJ19032.1 - 0.016 14.4 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase NAD_binding_10 PF13460.6 OAJ19032.1 - 0.046 13.6 0.4 0.63 9.9 0.1 2.2 1 1 1 2 2 2 0 NAD(P)H-binding ubiquitin PF00240.23 OAJ19032.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family SNARE_assoc PF09335.11 OAJ19033.1 - 1.5e-18 67.4 6.6 3.7e-18 66.1 6.6 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein DctQ PF04290.12 OAJ19033.1 - 0.18 11.8 8.5 0.79 9.6 0.4 2.7 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF4022 PF13214.6 OAJ19033.1 - 3.9 7.8 7.9 0.35 11.2 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) tRNA-synt_2 PF00152.20 OAJ19034.1 - 1.4e-84 283.9 0.0 4.5e-43 147.5 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ19034.1 - 4.9e-08 32.8 0.0 9.4e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AF-4 PF05110.13 OAJ19034.1 - 2.6 6.0 6.2 3.9 5.4 6.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SRPRB PF09439.10 OAJ19035.1 - 6.1e-07 29.0 0.0 2e-06 27.3 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 OAJ19035.1 - 0.00034 20.9 0.0 0.00066 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 OAJ19035.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 OAJ19035.1 - 0.014 15.2 0.0 0.92 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ19035.1 - 0.04 14.3 0.3 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 OAJ19035.1 - 0.043 13.8 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAJ19035.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAJ19035.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 OAJ19035.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Abhydrolase_6 PF12697.7 OAJ19036.1 - 0.00011 22.9 2.4 0.00011 22.9 2.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OAJ19036.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 OAJ19036.1 - 0.023 14.2 0.0 0.098 12.2 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAJ19036.1 - 0.094 12.4 0.5 0.44 10.2 0.5 1.9 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.25 OAJ19036.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) DUF4079 PF13301.6 OAJ19036.1 - 0.18 11.9 0.2 1.4 9.1 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Hydrolase_4 PF12146.8 OAJ19036.1 - 0.3 10.3 2.3 0.27 10.4 0.2 1.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 RCC1 PF00415.18 OAJ19037.1 - 4.1e-20 72.2 12.3 1.6e-06 28.6 0.2 8.0 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ19037.1 - 1.7e-10 40.4 19.1 5e-08 32.5 1.0 6.3 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat HAGH_C PF16123.5 OAJ19038.1 - 1.3e-18 67.3 0.0 2.5e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAJ19038.1 - 2.3e-09 37.6 2.8 4.8e-07 30.0 2.8 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAJ19038.1 - 0.041 13.4 0.1 0.068 12.7 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Cellulase PF00150.18 OAJ19039.1 - 1.5e-15 57.4 0.9 7.7e-15 55.1 0.9 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NDUFA12 PF05071.16 OAJ19041.1 - 6.4e-11 42.9 0.4 1.3e-10 42.0 0.4 1.5 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3678 PF12435.8 OAJ19042.1 - 0.078 12.4 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) UBX PF00789.20 OAJ19043.1 - 6.8e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 OAJ19043.1 - 0.0014 18.8 0.0 0.0034 17.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like DUF3080 PF11279.8 OAJ19043.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) U79_P34 PF03064.16 OAJ19043.1 - 0.43 9.9 7.5 0.75 9.1 7.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GBP_C PF02841.14 OAJ19043.1 - 0.63 9.4 6.5 1 8.7 6.5 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MFS_1 PF07690.16 OAJ19044.1 - 2.3e-36 125.4 34.3 2.3e-36 125.4 34.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ19044.1 - 2.4e-12 46.5 4.6 2.4e-12 46.5 4.6 2.8 2 1 1 4 4 4 1 Sugar (and other) transporter MFS_4 PF06779.14 OAJ19044.1 - 1.6e-07 31.0 1.5 1.6e-07 31.0 1.5 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 OAJ19044.1 - 0.0002 19.8 1.0 0.0053 15.1 2.5 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MMPL PF03176.15 OAJ19044.1 - 0.04 12.8 6.7 0.16 10.9 2.0 2.8 2 0 0 2 2 2 0 MMPL family SIS PF01380.22 OAJ19045.1 - 8.8e-15 54.7 0.0 9.6e-14 51.4 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 OAJ19045.1 - 0.00017 21.7 0.0 0.0092 16.0 0.0 2.3 1 1 1 2 2 2 2 SIS domain Glyco_hydro_38N PF01074.22 OAJ19046.1 - 9.2e-74 248.4 2.0 1.6e-73 247.6 2.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAJ19046.1 - 1.8e-47 162.2 0.0 5.6e-47 160.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAJ19046.1 - 1.3e-25 89.4 0.0 3.2e-25 88.1 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAJ19046.1 - 7.3e-08 32.4 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 OAJ19046.1 - 0.0014 17.9 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 SET PF00856.28 OAJ19047.1 - 3.1e-06 27.7 0.0 1.1e-05 25.9 0.0 1.9 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 OAJ19047.1 - 0.019 15.6 0.1 0.1 13.3 0.1 2.0 1 1 0 1 1 1 0 Rubisco LSMT substrate-binding F-box PF00646.33 OAJ19048.1 - 1.2e-07 31.4 3.3 9.8e-07 28.5 0.7 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ19048.1 - 1.5e-05 24.8 2.4 1.5e-05 24.8 2.4 2.6 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 OAJ19048.1 - 0.17 11.8 0.2 1 9.2 0.1 2.3 2 0 0 2 2 2 0 F-box Cellulase PF00150.18 OAJ19065.1 - 3.5e-11 43.1 1.9 5.4e-11 42.4 1.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AT_hook PF02178.19 OAJ19068.1 - 0.35 10.9 10.4 5.5 7.2 0.1 3.2 2 0 0 2 2 2 0 AT hook motif PI3K_1B_p101 PF10486.9 OAJ19068.1 - 6.1 4.5 9.2 10 3.8 9.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit AAA PF00004.29 OAJ19069.1 - 4.8e-43 146.7 0.0 7.8e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ19069.1 - 5.7e-12 45.2 0.7 2.4e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAJ19069.1 - 1.4e-10 41.0 0.1 3.3e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ19069.1 - 2.9e-07 30.6 0.1 3.9e-06 26.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ19069.1 - 4.2e-07 30.5 0.0 0.00023 21.6 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ19069.1 - 1.3e-06 28.6 0.0 8.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAJ19069.1 - 9.8e-06 25.4 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ19069.1 - 9.7e-05 22.7 0.2 0.0051 17.1 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 OAJ19069.1 - 0.00047 20.7 0.0 0.0033 18.0 0.0 2.3 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAJ19069.1 - 0.00088 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ19069.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ19069.1 - 0.0038 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ19069.1 - 0.0045 16.2 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ19069.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 OAJ19069.1 - 0.0068 16.1 0.0 0.032 13.9 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ19069.1 - 0.0075 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ19069.1 - 0.0083 15.9 0.1 0.04 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAJ19069.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 OAJ19069.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ19069.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ19069.1 - 0.014 15.7 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 OAJ19069.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 OAJ19069.1 - 0.032 13.9 0.3 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ19069.1 - 0.034 14.4 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ19069.1 - 0.045 13.1 0.1 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ19069.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ19069.1 - 0.068 12.7 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 OAJ19069.1 - 0.1 12.3 0.1 5.4 6.7 0.0 2.8 2 1 0 3 3 3 0 Thymidylate kinase NACHT PF05729.12 OAJ19069.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain CPT PF07931.12 OAJ19069.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 OAJ19069.1 - 1.4 9.4 4.0 12 6.4 0.2 2.5 2 1 0 2 2 2 0 AAA domain Clathrin PF00637.20 OAJ19070.1 - 4.2e-178 584.3 32.5 1.3e-33 115.9 0.1 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 OAJ19070.1 - 6.4e-33 111.5 2.9 6.5e-06 26.2 0.0 6.5 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 OAJ19070.1 - 7.6e-32 109.0 0.1 1.1e-30 105.4 0.1 3.0 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 OAJ19070.1 - 7.1e-09 34.9 0.5 2.1e-08 33.4 0.5 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 OAJ19070.1 - 0.00017 20.8 9.9 0.22 10.6 0.1 4.8 5 0 0 5 5 5 3 Coatomer WD associated region Rbsn PF11464.8 OAJ19070.1 - 0.016 14.9 0.7 0.62 9.8 0.0 3.4 3 0 0 3 3 3 0 Rabenosyn Rab binding domain TPR_7 PF13176.6 OAJ19070.1 - 0.022 14.7 8.6 49 4.3 0.1 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 OAJ19070.1 - 0.064 13.5 7.4 17 5.7 0.0 6.4 6 1 1 7 7 7 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 OAJ19070.1 - 0.13 12.4 16.8 9.2 6.7 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19070.1 - 2.5 8.9 3.9 97 3.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19070.1 - 3 7.8 16.5 12 5.9 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19070.1 - 8.7 7.5 24.4 42 5.3 0.2 9.9 10 2 2 12 12 11 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 OAJ19071.1 - 1.5e-27 96.9 0.3 7e-27 94.7 0.1 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SUR7 PF06687.12 OAJ19072.1 - 2.1e-22 79.8 2.0 2.8e-22 79.4 2.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.9 OAJ19072.1 - 0.085 11.6 0.7 0.11 11.2 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ost5 PF05251.12 OAJ19072.1 - 0.2 11.9 12.6 0.24 11.7 10.0 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF4131 PF13567.6 OAJ19072.1 - 4.3 7.0 8.2 9.8 5.8 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DnaJ_C PF01556.18 OAJ19073.1 - 6.6e-36 123.6 0.0 9.4e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ19073.1 - 1.5e-21 76.3 3.7 2.4e-21 75.6 3.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ19073.1 - 1.1e-09 38.5 18.7 2.7e-09 37.2 18.7 1.7 1 0 0 1 1 1 1 DnaJ central domain Cutinase PF01083.22 OAJ19075.1 - 2.5e-21 76.4 0.0 3.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.22 OAJ19076.1 - 4.4e-25 88.7 0.0 5.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ19076.1 - 9.4e-06 25.3 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 OAJ19076.1 - 0.0016 18.2 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 OAJ19076.1 - 0.0063 16.2 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 OAJ19076.1 - 0.0076 16.4 0.0 0.0089 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 OAJ19076.1 - 0.064 12.8 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 OAJ19076.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.11 OAJ19076.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF726 PF05277.12 OAJ19076.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF3089 PF11288.8 OAJ19076.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF900 PF05990.12 OAJ19076.1 - 0.23 10.9 0.0 1.1 8.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 OAJ19077.1 - 7.4e-25 87.9 0.1 8.9e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ19077.1 - 4.9e-05 23.0 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.12 OAJ19077.1 - 0.0014 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase FSH1 PF03959.13 OAJ19077.1 - 0.027 14.1 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF818 PF05677.12 OAJ19077.1 - 0.043 12.8 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 OAJ19077.1 - 0.059 12.6 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ19077.1 - 0.084 12.5 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 OAJ19077.1 - 0.087 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Cutinase PF01083.22 OAJ19078.1 - 8.1e-26 91.1 0.8 1e-25 90.8 0.8 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ19078.1 - 0.00051 19.7 0.1 0.00075 19.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.20 OAJ19078.1 - 0.0047 16.6 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 OAJ19078.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 OAJ19078.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Acetyltransf_1 PF00583.25 OAJ19079.1 - 1.8e-10 41.0 0.0 2.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ19079.1 - 4.4e-05 23.4 0.0 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ19079.1 - 0.00024 21.5 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ19079.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein MIS13 PF08202.11 OAJ19079.1 - 0.084 12.1 0.9 0.15 11.3 0.1 1.7 2 0 0 2 2 2 0 Mis12-Mtw1 protein family adh_short PF00106.25 OAJ19080.1 - 5.2e-23 81.5 3.0 3e-20 72.5 0.2 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19080.1 - 2.8e-20 72.9 1.7 3.1e-16 59.7 0.3 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ19080.1 - 5.1e-07 29.8 0.1 8.1e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Ribosomal_S27e PF01667.17 OAJ19081.1 - 2.4e-29 100.8 2.6 3.7e-29 100.2 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ19081.1 - 0.098 12.4 1.8 0.18 11.5 1.8 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ19081.1 - 0.23 11.3 4.6 0.59 10.0 0.3 2.5 1 1 2 3 3 3 0 Probable zinc-ribbon domain Ribosomal_S27e PF01667.17 OAJ19082.1 - 3.7e-29 100.2 2.6 3.7e-29 100.2 2.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ19082.1 - 0.13 12.0 2.2 0.24 11.1 2.2 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ19082.1 - 0.37 10.6 5.4 0.58 10.0 0.3 2.5 1 1 2 3 3 3 0 Probable zinc-ribbon domain AA_permease_2 PF13520.6 OAJ19083.1 - 4.6e-82 276.1 39.7 5.4e-82 275.9 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ19083.1 - 6.8e-19 67.8 35.3 1.4e-18 66.7 35.4 1.4 1 1 0 1 1 1 1 Amino acid permease DUF4131 PF13567.6 OAJ19083.1 - 4.6 6.9 20.6 2.1 8.0 1.5 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_L19e PF01280.20 OAJ19084.1 - 3.7e-60 202.2 10.7 3.7e-60 202.2 10.7 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 OAJ19084.1 - 0.022 14.5 1.5 0.029 14.1 0.2 2.0 2 0 0 2 2 2 0 S4 domain Ribonuc_L-PSP PF01042.21 OAJ19085.1 - 4.1e-40 136.6 0.0 5.3e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Zn_clus PF00172.18 OAJ19086.1 - 2.2e-08 34.1 27.2 6.5e-06 26.2 8.5 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain E7 PF00527.18 OAJ19086.1 - 4.6 7.5 14.1 0.044 14.0 1.8 3.1 3 0 0 3 3 3 0 E7 protein, Early protein CRA_rpt PF07046.11 OAJ19092.1 - 0.025 14.8 0.3 0.045 13.9 0.3 1.3 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TrbC PF04956.13 OAJ19092.1 - 9.9 6.5 11.2 5.5 7.3 0.3 4.2 4 0 0 4 4 4 0 TrbC/VIRB2 family SH3_1 PF00018.28 OAJ19093.1 - 3.6e-13 48.9 0.1 5.5e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ19093.1 - 6.9e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ19093.1 - 1.7e-07 30.8 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ19093.1 - 0.00075 19.5 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF962 PF06127.11 OAJ19093.1 - 0.0059 16.7 0.4 0.013 15.6 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SH3_3 PF08239.11 OAJ19093.1 - 0.032 14.5 0.3 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain SusE PF14292.6 OAJ19093.1 - 0.05 13.8 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 SusE outer membrane protein DUF4750 PF15938.5 OAJ19094.1 - 0.0031 17.1 1.0 0.0062 16.2 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) CRA_rpt PF07046.11 OAJ19094.1 - 0.015 15.5 1.3 0.03 14.5 1.3 1.5 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat TPR_12 PF13424.6 OAJ19095.1 - 2.1e-07 31.1 11.4 0.003 17.8 0.1 6.9 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19095.1 - 3.2e-07 29.9 8.5 0.047 13.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19095.1 - 5.3e-07 29.3 8.1 0.02 14.7 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19095.1 - 0.0013 19.4 3.9 3.4 8.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19095.1 - 0.0014 18.7 0.2 0.085 13.1 0.0 3.9 3 0 0 3 3 2 1 Tetratricopeptide repeat CDC45 PF02724.14 OAJ19095.1 - 0.014 13.7 0.5 0.024 12.9 0.5 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 OAJ19095.1 - 0.015 15.1 4.5 1.3 9.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19095.1 - 0.019 14.9 1.0 0.54 10.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19095.1 - 0.058 13.9 12.0 0.17 12.4 0.1 5.5 7 1 0 7 7 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ19095.1 - 0.19 11.8 4.9 40 4.4 0.0 5.5 6 1 0 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 OAJ19095.1 - 0.25 12.3 18.7 0.77 10.7 0.1 7.1 6 1 1 7 7 6 0 Tetratricopeptide repeat COPI_C PF06957.11 OAJ19095.1 - 1.3 7.7 5.0 1 8.1 3.4 1.6 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Gal4_dimer PF03902.13 OAJ19095.1 - 4.4 7.6 6.1 0.66 10.2 0.4 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain Phosducin PF02114.16 OAJ19096.1 - 0.86 8.5 4.4 7.8 5.4 5.2 2.0 2 0 0 2 2 2 0 Phosducin DUF2347 PF09804.9 OAJ19096.1 - 2.4 7.7 9.1 6.4 6.3 9.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DEAD PF00270.29 OAJ19097.1 - 1.3e-43 148.8 0.4 1.9e-43 148.3 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ19097.1 - 1.1e-27 96.6 0.6 7.9e-27 93.8 0.3 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ19097.1 - 0.00039 20.5 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ19097.1 - 0.0005 19.5 0.1 0.00097 18.5 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 OAJ19097.1 - 0.092 13.1 0.5 0.17 12.2 0.5 1.4 1 0 0 1 1 1 0 AAA domain Orbi_VP7 PF00897.17 OAJ19097.1 - 0.17 10.8 0.4 14 4.5 0.3 2.1 2 0 0 2 2 2 0 Orbivirus inner capsid protein VP7 DNA_ligase_A_M PF01068.21 OAJ19098.1 - 2.7e-38 131.7 0.0 3.3e-25 88.9 0.0 3.9 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ19098.1 - 4.5e-30 105.2 0.0 8.1e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAJ19098.1 - 1.8e-17 63.8 0.3 9.3e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region CDK2AP PF09806.9 OAJ19098.1 - 3.9 7.5 9.2 0.33 11.0 4.3 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Polysacc_deac_1 PF01522.21 OAJ19099.1 - 4.7e-21 75.0 0.2 1.3e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase SurE PF01975.17 OAJ19100.1 - 6.5e-38 130.5 0.0 9.5e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Sec10 PF07393.11 OAJ19101.1 - 1.2e-239 797.5 0.0 1.6e-239 797.1 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF812 PF05667.11 OAJ19101.1 - 0.00033 19.7 2.7 0.3 9.9 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF812) Spc7 PF08317.11 OAJ19101.1 - 0.0039 16.1 0.2 0.0083 15.0 0.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 OAJ19101.1 - 0.039 14.0 0.1 0.093 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Filament PF00038.21 OAJ19101.1 - 0.23 11.0 1.2 0.41 10.2 1.2 1.4 1 0 0 1 1 1 0 Intermediate filament protein Xpo1 PF08389.12 OAJ19102.1 - 1.2e-25 90.4 0.2 1.5e-24 86.8 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OAJ19102.1 - 1.9e-06 27.7 0.1 6.4e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OAJ19102.1 - 0.0053 16.9 0.0 0.037 14.2 0.0 2.4 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OAJ19102.1 - 0.011 16.0 0.3 0.23 11.8 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat RasGEF_N_2 PF14663.6 OAJ19102.1 - 0.015 15.7 0.2 0.86 10.0 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FerA PF08165.11 OAJ19102.1 - 0.051 13.5 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 FerA (NUC095) domain TetR_C_22 PF17928.1 OAJ19102.1 - 0.15 12.4 0.9 6.3 7.2 0.0 3.5 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HEAT_EZ PF13513.6 OAJ19102.1 - 0.85 10.2 9.1 4.1 8.0 0.0 5.7 5 1 0 5 5 5 0 HEAT-like repeat Indigoidine_A PF04227.12 OAJ19103.1 - 1.3e-111 372.6 1.7 2.1e-111 371.9 1.7 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAJ19103.1 - 2.1e-18 66.7 0.0 5.4e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ARGLU PF15346.6 OAJ19103.1 - 0.058 13.3 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Trm112p PF03966.16 OAJ19104.1 - 1.5e-18 67.1 0.1 1.9e-18 66.8 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-RING_7 PF02591.15 OAJ19104.1 - 0.059 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain DUF2433 PF10360.9 OAJ19105.1 - 6.2e-45 152.3 0.1 9.6e-45 151.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 OAJ19105.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GTP_EFTU PF00009.27 OAJ19107.1 - 5.2e-33 114.2 0.0 3.1e-32 111.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAJ19107.1 - 3.7e-17 62.4 0.0 1.2e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAJ19107.1 - 1.4e-10 41.5 15.9 7.6e-10 39.0 0.2 4.0 4 1 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ19107.1 - 1.8e-06 28.0 0.1 9.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ19107.1 - 0.00021 21.5 0.0 0.00062 20.0 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 OAJ19107.1 - 0.0014 18.5 0.2 0.0046 16.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ras PF00071.22 OAJ19107.1 - 0.078 12.6 0.1 0.44 10.1 0.0 2.4 1 1 1 2 2 2 0 Ras family Abhydrolase_3 PF07859.13 OAJ19108.1 - 8e-30 104.3 0.0 1.1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ19108.1 - 0.0022 16.9 0.0 0.0043 16.0 0.0 1.4 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAJ19108.1 - 0.0088 15.5 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family GYF PF02213.16 OAJ19109.1 - 1.1e-18 66.6 1.4 2.1e-18 65.7 1.4 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAJ19109.1 - 2.1e-05 24.2 0.1 6.1e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 GYF domain 2 TAF4 PF05236.14 OAJ19109.1 - 5.5 6.6 6.5 6.4 6.4 0.0 3.0 2 1 1 3 3 3 0 Transcription initiation factor TFIID component TAF4 family Polysacc_deac_1 PF01522.21 OAJ19110.1 - 7.4e-23 80.8 0.0 7.8e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase PAP1 PF08601.10 OAJ19110.1 - 0.2 11.4 4.5 0.3 10.8 4.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Secretin_N PF03958.17 OAJ19110.1 - 1.1 9.7 3.8 2.6 8.5 3.8 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain SpoIIIAH PF12685.7 OAJ19110.1 - 2.5 7.9 5.6 4 7.2 5.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein TPR_12 PF13424.6 OAJ19111.1 - 1.8e-09 37.7 15.0 0.022 15.0 0.2 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19111.1 - 4.4e-05 23.3 11.0 0.33 11.2 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19111.1 - 0.00023 20.9 22.1 0.021 14.7 0.2 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19111.1 - 0.00088 19.1 9.1 0.75 10.0 0.1 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19111.1 - 0.0041 17.2 5.4 24 5.5 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19111.1 - 0.02 14.7 0.6 8.9 6.3 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19111.1 - 0.049 14.3 2.7 0.44 11.2 0.3 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19111.1 - 0.15 12.6 19.8 0.83 10.2 0.1 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19111.1 - 0.41 11.6 23.3 0.5 11.3 0.1 8.0 9 1 1 10 10 10 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ19111.1 - 1 10.2 16.6 0.2 12.4 1.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat CLP1_P PF16575.5 OAJ19112.1 - 2.2e-26 92.8 0.0 3e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OAJ19112.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ19112.1 - 0.039 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoLip_ATPase_C PF16212.5 OAJ19113.1 - 7.8e-73 245.3 31.8 7.8e-73 245.3 31.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ19113.1 - 1.2e-21 76.2 0.6 1.2e-21 76.2 0.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ19113.1 - 8.2e-13 49.1 1.3 2.2e-05 24.9 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ19113.1 - 4.4e-12 45.9 0.0 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAJ19113.1 - 9.2e-06 25.3 0.0 9.2e-06 25.3 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ19113.1 - 0.0029 17.4 0.1 0.008 15.9 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spt5_N PF11942.8 OAJ19113.1 - 0.28 12.2 7.7 2.6 9.1 3.7 3.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal WD40 PF00400.32 OAJ19114.1 - 9.6e-23 80.0 14.2 8e-10 39.2 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19114.1 - 6e-08 32.9 0.5 0.075 13.3 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ19114.1 - 0.0035 16.4 0.0 0.048 12.6 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ19114.1 - 0.017 13.8 0.1 3.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Lactamase_B PF00753.27 OAJ19130.1 - 6.7e-09 36.0 2.3 0.00049 20.2 0.1 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 OAJ19130.1 - 9.3e-07 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 OAJ19130.1 - 0.0089 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HORMA PF02301.18 OAJ19131.1 - 1.2e-35 123.1 0.0 2.6e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 OAJ19131.1 - 9.2e-08 31.9 5.9 1.6e-07 31.1 5.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ19131.1 - 0.002 17.7 3.5 0.0034 16.9 3.5 1.3 1 0 0 1 1 1 1 PHD-finger Malate_synthase PF01274.22 OAJ19132.1 - 9.2e-204 677.6 0.0 1.1e-203 677.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase BRAP2 PF07576.12 OAJ19133.1 - 2.5e-27 95.0 0.1 6e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAJ19133.1 - 4.4e-18 65.4 3.5 1.2e-17 64.0 3.5 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAJ19133.1 - 2.3e-08 34.2 10.3 2.3e-08 34.2 10.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAJ19133.1 - 4.4e-06 26.9 6.4 4.4e-06 26.9 6.4 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ19133.1 - 3.3e-05 23.7 9.4 3.3e-05 23.7 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ19133.1 - 3.4e-05 23.8 4.5 0.00013 21.9 4.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ19133.1 - 0.00012 21.8 10.4 0.00012 21.8 10.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ19133.1 - 0.00024 20.8 4.1 0.00024 20.8 4.1 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 OAJ19133.1 - 0.00064 19.7 4.2 0.0016 18.5 4.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 OAJ19133.1 - 0.00069 19.5 8.2 0.00069 19.5 8.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ19133.1 - 0.011 15.6 7.6 0.011 15.6 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAJ19133.1 - 0.047 13.5 7.0 0.1 12.4 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Filament PF00038.21 OAJ19133.1 - 0.077 12.6 16.9 0.13 11.8 16.9 1.3 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 OAJ19133.1 - 0.16 12.4 13.3 0.37 11.2 13.3 1.6 1 0 0 1 1 1 0 Fez1 zf-C3HC4_4 PF15227.6 OAJ19133.1 - 1.1 9.4 5.8 4.5 7.5 5.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4407 PF14362.6 OAJ19133.1 - 2.2 7.5 16.7 69 2.6 15.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 OAJ19133.1 - 2.3 8.0 15.4 5.6 6.8 4.0 3.4 3 1 0 3 3 3 0 Septum formation initiator YabA PF06156.13 OAJ19133.1 - 2.3 8.9 8.7 9.1 7.0 0.5 2.6 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 OAJ19133.1 - 2.5 8.6 4.3 3.1 8.2 0.3 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 OAJ19133.1 - 5.5 5.8 15.4 12 4.7 15.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 OAJ19133.1 - 6.5 6.8 9.5 5.3 7.1 1.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SAPS PF04499.15 OAJ19134.1 - 3.4e-145 484.6 0.0 9.5e-145 483.1 0.0 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein PQ-loop PF04193.14 OAJ19136.1 - 5.8e-18 64.4 20.8 5.2e-12 45.4 0.2 3.3 4 0 0 4 4 4 2 PQ loop repeat BSP_II PF05432.11 OAJ19136.1 - 0.02 14.6 0.6 0.028 14.1 0.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 OAJ19136.1 - 0.042 13.5 2.0 0.66 9.6 1.6 2.3 2 0 0 2 2 2 0 FAM176 family DUF3328 PF11807.8 OAJ19136.1 - 0.061 13.1 0.5 3.2 7.5 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Bindin PF02084.15 OAJ19136.1 - 0.14 12.5 1.8 0.24 11.6 1.8 1.3 1 0 0 1 1 1 0 Bindin DUF2207 PF09972.9 OAJ19136.1 - 1.7 7.4 8.0 1.3 7.6 0.0 3.1 2 2 0 2 2 2 0 Predicted membrane protein (DUF2207) DNA_pol_phi PF04931.13 OAJ19136.1 - 2.1 6.3 5.4 3.2 5.8 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi MtN3_slv PF03083.16 OAJ19136.1 - 4.1 7.5 11.7 8.4 6.5 0.3 3.2 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4637 PF15470.6 OAJ19136.1 - 4.4 7.0 6.5 7.4 6.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) F-box-like PF12937.7 OAJ19137.1 - 0.00032 20.5 1.7 0.0007 19.4 0.4 2.2 2 0 0 2 2 2 1 F-box-like VTC PF09359.10 OAJ19138.1 - 9.3e-98 327.0 0.1 4e-97 324.9 0.0 2.0 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 OAJ19138.1 - 1e-17 65.2 20.5 1.2e-06 28.8 0.5 4.4 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 OAJ19138.1 - 4e-14 52.8 0.9 1.2e-13 51.3 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ribosomal_60s PF00428.19 OAJ19138.1 - 1.5 9.4 7.8 0.87 10.2 0.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Annexin PF00191.20 OAJ19139.1 - 1.9e-51 172.0 0.4 2.7e-13 49.8 0.0 4.1 4 0 0 4 4 4 4 Annexin RVT_1 PF00078.27 OAJ19140.1 - 5e-24 85.1 0.0 8.8e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ19140.1 - 1.2e-20 73.4 0.0 3.7e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ19140.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ19140.1 - 1.5e-14 54.1 0.0 2.3e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ19140.1 - 2.4e-10 40.6 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ19140.1 - 0.00043 20.9 2.0 0.013 16.2 0.0 3.6 4 0 0 4 4 4 1 Aspartyl protease Herpes_ORF11 PF04797.13 OAJ19140.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Aminotran_3 PF00202.21 OAJ19141.1 - 1.6e-91 307.0 0.0 2.5e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III NDK PF00334.19 OAJ19142.1 - 0.00093 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF148 PF02520.17 OAJ19143.1 - 0.47 10.6 5.2 0.072 13.2 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 Pes-10 PF07149.11 OAJ19143.1 - 2.8 6.9 6.0 3.5 6.6 6.0 1.1 1 0 0 1 1 1 0 Pes-10 Aminotran_1_2 PF00155.21 OAJ19145.1 - 6.4e-15 55.2 0.0 7.9e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAJ19145.1 - 2.3e-05 23.4 0.0 3.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pkinase PF00069.25 OAJ19146.1 - 3.5e-64 216.7 0.0 1.1e-32 113.5 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19146.1 - 7.8e-29 100.7 0.0 6.5e-14 51.8 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 OAJ19146.1 - 1.2e-18 67.6 10.0 2e-18 66.9 0.0 3.7 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs RWD PF05773.22 OAJ19146.1 - 1.5e-18 67.1 0.0 4.7e-18 65.6 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 OAJ19146.1 - 2.4e-13 50.0 1.4 1.4e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 OAJ19146.1 - 9.7e-05 22.4 0.0 9.7e-05 22.4 0.0 3.8 5 1 0 5 5 5 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAJ19146.1 - 0.0014 18.3 0.0 1.8 8.2 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OAJ19146.1 - 0.0029 17.0 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ19146.1 - 0.0043 15.9 3.1 0.015 14.1 0.1 2.4 2 1 0 2 2 2 1 Fungal protein kinase UQ_con PF00179.26 OAJ19146.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme NOA36 PF06524.12 OAJ19146.1 - 2.1 7.6 8.1 4.2 6.6 8.1 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 OAJ19146.1 - 8 5.7 16.0 7.9 5.7 9.2 2.4 2 0 0 2 2 2 0 BUD22 Methyltransf_16 PF10294.9 OAJ19147.1 - 1.8e-16 60.4 0.0 7.9e-15 55.0 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ19147.1 - 0.056 14.1 0.0 0.18 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ19147.1 - 0.06 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DPBB_1 PF03330.18 OAJ19148.1 - 0.0015 18.8 0.1 0.0039 17.4 0.1 1.8 1 0 0 1 1 1 1 Lytic transglycolase TAF4 PF05236.14 OAJ19150.1 - 1.2e-29 103.9 30.1 3e-22 79.7 12.4 3.6 1 1 1 2 2 2 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 OAJ19150.1 - 0.75 9.5 0.0 0.75 9.5 0.0 2.3 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4609 PF15382.6 OAJ19150.1 - 5.6 6.9 7.7 0.2 11.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4609) Y_phosphatase PF00102.27 OAJ19151.1 - 4.2e-31 108.3 0.0 3.6e-15 56.2 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ19151.1 - 3e-06 27.1 0.0 1.4e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain GPI PF06560.11 OAJ19151.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FA_hydroxylase PF04116.13 OAJ19152.1 - 3e-22 79.4 15.7 3e-22 79.4 15.7 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 OAJ19153.1 - 1.6e-22 79.3 1.0 1.7e-07 31.8 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAJ19153.1 - 0.0017 17.0 0.0 0.031 12.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Zn_clus PF00172.18 OAJ19154.1 - 7.2e-10 38.8 8.9 1.2e-09 38.1 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vma12 PF11712.8 OAJ19154.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PP2C PF00481.21 OAJ19174.1 - 7e-28 97.9 0.0 2.3e-26 93.0 0.0 2.7 2 0 0 2 2 2 1 Protein phosphatase 2C SUIM_assoc PF16619.5 OAJ19174.1 - 0.023 14.8 28.5 0.12 12.5 0.3 4.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF4136 PF13590.6 OAJ19174.1 - 0.057 14.0 1.9 0.11 13.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) AAA PF00004.29 OAJ19175.1 - 2.1e-22 80.0 0.0 3.7e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ19175.1 - 0.00081 19.8 3.2 0.0087 16.5 1.7 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 OAJ19175.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ19175.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain MukB PF04310.12 OAJ19175.1 - 0.091 12.5 0.2 8.4 6.1 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_7 PF12775.7 OAJ19175.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region LRR_4 PF12799.7 OAJ19177.1 - 2.3e-08 34.2 2.2 0.47 10.9 0.1 5.8 3 2 3 7 7 7 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ19177.1 - 2.1e-07 30.4 14.1 13 6.2 0.1 10.1 11 0 0 11 11 11 3 Leucine Rich repeat F-box-like PF12937.7 OAJ19177.1 - 6.7e-06 25.9 5.6 7.6e-06 25.7 2.6 2.5 2 0 0 2 2 2 1 F-box-like DUF4407 PF14362.6 OAJ19177.1 - 0.1 11.9 4.3 1.4 8.2 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 OAJ19177.1 - 0.5 10.8 8.9 3 8.3 3.0 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CRAL_TRIO PF00650.20 OAJ19178.1 - 5.6e-35 120.4 0.0 8.8e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ19178.1 - 7e-11 42.1 1.1 1.3e-10 41.3 0.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain ABC_membrane PF00664.23 OAJ19179.1 - 2.9e-72 243.6 24.3 1.8e-37 129.5 9.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ19179.1 - 1.3e-58 197.4 0.0 1.2e-28 100.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ19179.1 - 5.2e-16 58.8 1.6 4.4e-08 32.8 0.5 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ19179.1 - 2.8e-09 37.1 0.0 0.0016 18.4 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 OAJ19179.1 - 1.6e-07 30.9 1.7 0.002 17.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ19179.1 - 4.4e-06 27.0 0.6 0.03 14.6 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 OAJ19179.1 - 1e-05 25.4 0.3 0.072 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 OAJ19179.1 - 2.3e-05 24.8 4.3 0.09 13.1 0.0 4.2 4 1 0 4 4 4 2 AAA ATPase domain AAA_7 PF12775.7 OAJ19179.1 - 0.00036 20.1 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ19179.1 - 0.00056 20.1 0.2 0.06 13.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 OAJ19179.1 - 0.001 18.0 0.2 0.49 9.1 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAJ19179.1 - 0.001 18.7 0.5 0.3 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 OAJ19179.1 - 0.0015 18.4 0.0 0.63 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAJ19179.1 - 0.0018 18.7 0.6 0.31 11.5 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAJ19179.1 - 0.0021 18.6 0.1 1.2 9.7 0.1 3.4 4 0 0 4 4 3 1 AAA domain T2SSE PF00437.20 OAJ19179.1 - 0.0022 17.1 0.0 0.039 13.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 OAJ19179.1 - 0.0028 18.2 0.3 0.24 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ19179.1 - 0.0062 16.6 0.2 6.8 6.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 OAJ19179.1 - 0.016 15.3 0.8 0.33 11.0 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 OAJ19179.1 - 0.024 14.9 4.3 2 8.7 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 OAJ19179.1 - 0.03 14.0 0.0 3 7.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAJ19179.1 - 0.061 12.6 0.2 1.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 OAJ19179.1 - 0.07 13.5 0.1 2.6 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 OAJ19179.1 - 0.091 12.8 0.6 16 5.5 0.1 2.8 3 0 0 3 3 2 0 Dynamin family AAA_5 PF07728.14 OAJ19179.1 - 0.14 12.2 0.1 5.2 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 OAJ19179.1 - 0.16 11.3 0.7 5 6.4 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3987 PF13148.6 OAJ19179.1 - 1.8 7.5 6.0 4.7 6.1 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) GST_C_3 PF14497.6 OAJ19180.1 - 3.4e-26 91.3 0.0 7.2e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ19180.1 - 2.9e-05 24.2 0.0 6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ19180.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADH_u_ox_C PF12853.7 OAJ19180.1 - 0.068 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit YL1 PF05764.13 OAJ19181.1 - 0.0041 17.3 0.4 0.0041 17.3 0.4 2.4 3 0 0 3 3 3 1 YL1 nuclear protein PHINT_rpt PF14882.6 OAJ19181.1 - 0.14 12.5 0.2 0.41 11.0 0.2 1.8 1 0 0 1 1 1 0 Phage-integrase repeat unit CDC45 PF02724.14 OAJ19181.1 - 0.57 8.4 8.4 0.012 14.0 1.1 1.8 2 0 0 2 2 2 0 CDC45-like protein zf-RING_2 PF13639.6 OAJ19183.1 - 4e-12 46.3 4.3 8.8e-12 45.2 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ19183.1 - 1e-10 41.2 1.7 1e-10 41.2 1.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ19183.1 - 1.6e-06 27.8 3.6 3.2e-06 26.9 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 OAJ19183.1 - 1.3e-05 25.2 0.0 0.00019 21.4 0.0 2.7 2 0 0 2 2 2 1 PA domain zf-RING_5 PF14634.6 OAJ19183.1 - 3e-05 23.9 2.0 5.4e-05 23.1 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ19183.1 - 4.3e-05 23.3 1.6 8.6e-05 22.3 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ19183.1 - 0.00045 20.2 0.2 0.00045 20.2 0.2 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAJ19183.1 - 0.00073 19.8 4.7 0.0026 18.0 4.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAJ19183.1 - 0.0017 18.2 5.7 0.0037 17.1 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ19183.1 - 0.037 14.1 1.9 0.073 13.1 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 OAJ19183.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zinc_ribbon_16 PF17034.5 OAJ19183.1 - 0.17 12.1 1.1 0.36 11.1 1.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 OAJ19183.1 - 0.37 10.7 5.5 0.96 9.4 5.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MWFE PF15879.5 OAJ19184.1 - 7.6e-25 86.8 0.8 9.6e-25 86.5 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RhoGEF PF00621.20 OAJ19185.1 - 1.2e-12 48.4 0.0 7.7e-09 36.0 0.0 2.7 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.29 OAJ19185.1 - 0.062 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 PH domain RRM_1 PF00076.22 OAJ19189.1 - 1.4e-05 24.8 0.0 0.022 14.6 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.10 OAJ19189.1 - 0.00086 19.6 7.3 0.00086 19.6 7.3 1.9 2 0 0 2 2 2 1 Centromere protein B dimerisation domain DUF3537 PF12056.8 OAJ19189.1 - 0.024 13.5 0.5 0.042 12.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FAM60A PF15396.6 OAJ19189.1 - 1.6 8.7 9.1 0.35 10.9 0.9 2.3 2 0 0 2 2 2 0 Protein Family FAM60A ABC_trans_N PF14510.6 OAJ19189.1 - 4.4 8.0 6.2 1.3 9.6 1.4 2.4 2 0 0 2 2 2 0 ABC-transporter N-terminal Myc_N PF01056.18 OAJ19189.1 - 5 6.9 9.9 0.99 9.2 6.1 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Complex1_LYR PF05347.15 OAJ19190.1 - 9.6e-08 32.0 7.9 1e-07 31.9 5.9 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Ras PF00071.22 OAJ19191.1 - 1.2e-27 96.6 0.0 2.2e-26 92.4 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OAJ19191.1 - 5.4e-26 91.2 0.0 8.3e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ19191.1 - 6.5e-05 22.5 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ19191.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ19191.1 - 0.0084 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase UPF0052 PF01933.18 OAJ19192.1 - 1.4e-40 139.4 0.0 4e-40 137.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Aldedh PF00171.22 OAJ19194.1 - 1.2e-158 528.5 0.3 1.3e-158 528.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 OAJ19195.1 - 3.9e-67 226.4 0.0 4.7e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19195.1 - 1.4e-33 116.3 0.0 4.7e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ19195.1 - 0.00091 18.6 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ19195.1 - 0.0051 16.2 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ19195.1 - 0.0051 15.8 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain NDUF_B4 PF07225.12 OAJ19195.1 - 0.08 12.8 0.1 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) APH PF01636.23 OAJ19195.1 - 0.088 12.7 0.2 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ19195.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 OAJ19195.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Ank_4 PF13637.6 OAJ19196.1 - 3e-10 40.4 0.2 3.4e-06 27.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ19196.1 - 1e-08 35.7 0.0 2.4e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ19196.1 - 2.1e-06 27.9 0.0 5.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ19196.1 - 9.2e-06 25.6 0.0 7e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 OAJ19196.1 - 3.9e-05 23.9 0.0 9.5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Methyltransf_25 PF13649.6 OAJ19196.1 - 0.00041 21.0 0.0 0.00093 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ19196.1 - 0.0042 18.1 0.0 0.066 14.2 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ19196.1 - 0.0044 17.6 0.0 0.0087 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TB2_DP1_HVA22 PF03134.19 OAJ19197.1 - 1.2e-06 28.3 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pkinase PF00069.25 OAJ19211.1 - 2.5e-74 250.0 0.0 3.1e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19211.1 - 1.9e-35 122.4 0.0 2.9e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ19211.1 - 0.0035 16.7 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ19211.1 - 0.0077 15.2 0.0 0.3 10.0 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain PEX11 PF05648.14 OAJ19213.1 - 1.4e-14 54.1 0.0 1.2e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) KilA-N PF04383.13 OAJ19214.1 - 0.00022 21.0 0.1 0.00075 19.3 0.1 1.9 1 1 0 1 1 1 1 KilA-N domain HSP20 PF00011.21 OAJ19215.1 - 2.8e-17 62.7 0.3 6.7e-10 39.0 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAJ19215.1 - 1.5e-05 24.4 0.0 7.5e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF1326 PF07040.11 OAJ19215.1 - 0.12 12.4 1.4 0.18 11.8 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Vert_HS_TF PF06546.11 OAJ19215.1 - 0.79 9.3 4.1 4.7 6.8 0.1 2.1 1 1 0 2 2 2 0 Vertebrate heat shock transcription factor L51_S25_CI-B8 PF05047.16 OAJ19216.1 - 4.1e-10 39.4 0.1 6.4e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ufd2P_core PF10408.9 OAJ19218.1 - 1.6e-201 671.2 0.0 1.9e-201 670.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAJ19218.1 - 2.5e-26 91.7 0.3 6.6e-26 90.3 0.3 1.8 1 0 0 1 1 1 1 U-box domain AP1AR PF15745.5 OAJ19218.1 - 0.27 10.8 0.0 0.27 10.8 0.0 2.3 3 0 0 3 3 3 0 AP-1 complex-associated regulatory protein Abhydrolase_1 PF00561.20 OAJ19220.1 - 8.5e-20 71.5 0.3 5.7e-07 29.4 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ19220.1 - 1.6e-14 55.0 1.3 3e-14 54.2 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ19220.1 - 0.00069 19.0 0.1 0.0014 18.0 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 SKN1 PF03935.15 OAJ19221.1 - 5.2e-170 566.1 0.0 8.1e-170 565.5 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Ribophorin_II PF05817.14 OAJ19222.1 - 8.2e-10 37.9 2.3 6.6e-09 34.9 0.5 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II RIC1 PF07064.13 OAJ19223.1 - 1.1e-91 306.7 0.0 1.6e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OAJ19223.1 - 0.011 16.0 0.1 0.65 10.3 0.1 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Amidohydro_2 PF04909.14 OAJ19224.1 - 1.6e-05 24.8 0.0 0.0002 21.2 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase Pkinase PF00069.25 OAJ19226.1 - 3.3e-61 207.0 2.3 1.4e-60 205.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19226.1 - 4.5e-26 91.7 1.1 5.2e-20 71.8 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ19226.1 - 1e-07 31.3 0.0 1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 OAJ19226.1 - 0.0045 16.4 0.0 0.016 14.6 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ19226.1 - 0.052 12.3 0.0 0.052 12.3 0.0 2.2 2 1 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 OAJ19226.1 - 0.1 11.9 0.0 0.1 11.9 0.0 3.0 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 OAJ19226.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ19226.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 OAJ19226.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RHH_4 PF13467.6 OAJ19227.1 - 0.02 14.8 0.8 0.036 13.9 0.8 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain ETC_C1_NDUFA5 PF04716.14 OAJ19228.1 - 9.5e-23 79.8 0.1 1.3e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region zf-C2H2 PF00096.26 OAJ19229.1 - 0.00051 20.3 15.1 0.017 15.5 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ19229.1 - 0.013 16.3 14.3 0.4 11.6 3.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ19229.1 - 1 9.4 3.2 1.1 9.4 1.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Rad51 PF08423.11 OAJ19230.1 - 4.9e-14 52.2 0.1 9.7e-12 44.7 0.0 2.8 3 0 0 3 3 3 1 Rad51 RecA PF00154.21 OAJ19230.1 - 1.8e-05 24.3 0.1 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAJ19230.1 - 0.0001 22.0 0.2 0.00031 20.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 OAJ19230.1 - 0.00014 21.3 0.1 0.00035 20.0 0.1 1.6 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 OAJ19230.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 OAJ19230.1 - 0.1 11.7 0.8 0.61 9.2 0.2 2.2 2 0 0 2 2 2 0 PAXNEB protein DEAD PF00270.29 OAJ19231.1 - 1.4e-45 155.2 0.0 3.6e-45 153.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ19231.1 - 1.4e-31 109.1 0.0 2.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAJ19231.1 - 0.0042 15.9 0.0 0.0068 15.2 0.0 1.3 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAJ19231.1 - 0.056 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Glyoxalase PF00903.25 OAJ19232.1 - 4.9e-05 23.5 0.0 0.00052 20.2 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAJ19232.1 - 0.048 13.6 0.0 5.7 6.9 0.0 2.9 4 0 0 4 4 4 0 Glyoxalase-like domain eIF3_subunit PF08597.10 OAJ19232.1 - 4.7 7.1 10.3 0.17 11.8 2.8 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Acyl-CoA_dh_1 PF00441.24 OAJ19234.1 - 2.1e-28 99.4 1.9 3.3e-28 98.8 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ19234.1 - 2.8e-18 65.9 0.0 6.8e-18 64.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ19234.1 - 1.5e-12 47.9 2.5 1.5e-12 47.9 2.5 2.0 1 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ19234.1 - 2.3e-10 41.1 0.0 4.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 OAJ19234.1 - 0.044 13.4 0.0 0.69 9.5 0.0 2.3 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.17 OAJ19235.1 - 5e-83 277.8 0.1 8.6e-83 277.0 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAJ19235.1 - 5.8e-71 238.3 0.0 1.1e-70 237.4 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAJ19235.1 - 6.1e-40 136.2 0.0 1.6e-39 134.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ19235.1 - 4.6e-31 107.1 0.0 1.4e-30 105.5 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAJ19235.1 - 2.3e-28 99.5 0.0 4.7e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAJ19235.1 - 1.5e-15 56.8 0.8 3.1e-15 55.8 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ19235.1 - 1.1e-12 47.6 0.2 7.1e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 OAJ19235.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ19235.1 - 1e-07 31.7 0.1 3e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ19235.1 - 7e-06 26.7 0.3 0.12 13.1 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 OAJ19235.1 - 2.7e-05 24.3 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 OAJ19235.1 - 3.8e-05 23.0 0.1 0.0073 15.5 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 OAJ19235.1 - 0.00092 18.9 0.0 0.0032 17.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 OAJ19235.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAJ19235.1 - 0.0063 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 OAJ19235.1 - 0.012 15.1 0.3 0.023 14.1 0.3 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 OAJ19235.1 - 0.073 12.3 0.0 0.19 10.9 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 OAJ19235.1 - 0.11 12.4 1.5 1.4 8.8 0.3 3.0 2 1 1 3 3 3 0 Glycine cleavage H-protein PNPase PF03726.14 OAJ19235.1 - 1 9.9 3.0 1.5 9.3 0.2 2.6 3 0 0 3 3 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain SAE2 PF08573.10 OAJ19236.1 - 4.3e-12 47.1 1.0 4.3e-12 47.1 1.0 3.5 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SATase_N PF06426.14 OAJ19236.1 - 0.019 15.3 1.5 1.2 9.6 0.2 2.7 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal cobW PF02492.19 OAJ19238.1 - 7.8e-32 110.3 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAJ19238.1 - 0.0019 17.3 2.2 0.012 14.6 2.2 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ19238.1 - 0.018 15.6 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAJ19238.1 - 0.027 14.6 0.0 0.23 11.6 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ19238.1 - 0.04 14.3 0.0 0.055 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CbtA PF09490.10 OAJ19238.1 - 0.044 13.6 0.3 0.066 13.0 0.3 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) ABC_tran PF00005.27 OAJ19238.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 OAJ19238.1 - 0.12 11.5 0.0 0.18 10.8 0.0 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 OAJ19238.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SelP_N PF04592.14 OAJ19238.1 - 0.2 11.0 13.4 0.3 10.5 13.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ten1_2 PF15490.6 OAJ19239.1 - 3.4e-06 26.8 0.0 1.3e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit RNA_Me_trans PF04252.13 OAJ19241.1 - 4.9e-64 215.6 0.0 5.9e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase TPP_enzyme_M PF00205.22 OAJ19242.1 - 1.5e-23 83.0 0.0 3.6e-22 78.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAJ19242.1 - 2.6e-15 56.5 0.0 8.9e-15 54.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 OAJ19242.1 - 5e-11 42.5 0.1 9.4e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain CO_dh PF02552.16 OAJ19242.1 - 0.18 11.6 0.0 0.59 9.9 0.0 1.8 3 0 0 3 3 3 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit POP1 PF06978.11 OAJ19255.1 - 8.4e-25 88.0 19.1 8.4e-25 88.0 19.1 3.2 2 2 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAJ19255.1 - 1.9e-16 60.2 0.0 1.9e-16 60.2 0.0 2.6 2 0 0 2 2 2 1 POPLD (NUC188) domain YL1 PF05764.13 OAJ19255.1 - 0.0016 18.6 5.0 0.0016 18.6 5.0 3.0 3 0 0 3 3 3 1 YL1 nuclear protein TFIIF_alpha PF05793.12 OAJ19255.1 - 0.18 10.4 17.3 0.36 9.4 17.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 OAJ19255.1 - 0.22 10.8 18.4 0.56 9.5 18.4 1.6 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ19255.1 - 0.28 9.3 11.8 0.41 8.8 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ferlin_C PF16165.5 OAJ19255.1 - 1.1 9.2 4.3 27 4.7 0.0 2.4 2 0 0 2 2 2 0 Ferlin C-terminus Spt5_N PF11942.8 OAJ19255.1 - 1.3 10.0 16.0 6.7 7.8 16.0 2.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 OAJ19255.1 - 5.5 5.2 14.2 8.9 4.5 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 OAJ19256.1 - 1.8e-07 30.7 13.8 0.32 10.9 0.0 8.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19256.1 - 6.8e-07 28.9 20.5 0.24 11.6 0.0 8.9 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ19256.1 - 2.9e-05 24.1 0.2 53 4.5 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19256.1 - 0.0061 16.8 1.2 0.028 14.7 0.4 7.6 8 1 2 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19256.1 - 0.015 15.5 15.0 24 5.5 0.4 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ19256.1 - 0.13 12.4 4.0 0.39 10.8 0.5 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 OAJ19256.1 - 0.18 11.5 7.5 5.4 6.8 0.0 6.0 8 0 0 8 8 8 0 TPR repeat TPR_19 PF14559.6 OAJ19256.1 - 6.7 7.3 40.2 1 9.9 0.0 9.5 8 2 2 10 10 10 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.22 OAJ19257.1 - 0.73 10.1 6.7 1.3 9.3 6.7 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3439 PF11921.8 OAJ19257.1 - 7.3 6.6 10.7 15 5.6 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Synapsin_N PF10581.9 OAJ19258.1 - 1.1e-19 70.0 6.4 80 3.3 0.0 18.4 7 5 13 20 20 20 0 Synapsin N-terminal MgtE_N PF03448.17 OAJ19258.1 - 1.2e-19 70.8 0.0 0.016 15.8 0.0 4.9 1 1 3 5 5 5 5 MgtE intracellular N domain F-box PF00646.33 OAJ19258.1 - 2.4e-05 24.1 0.9 1e+02 2.9 0.0 7.8 5 3 1 8 8 8 0 F-box domain DUF3432 PF11914.8 OAJ19258.1 - 0.036 14.3 1.0 0.036 14.3 1.0 6.4 1 1 6 8 8 8 0 Domain of unknown function (DUF3432) SOG2 PF10428.9 OAJ19258.1 - 1.4 8.0 17.4 2.3 7.3 17.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein V-ATPase_H_C PF11698.8 OAJ19259.1 - 3.4e-07 30.4 0.0 6.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 OAJ19259.1 - 0.077 13.3 1.1 0.17 12.2 0.2 2.1 1 1 1 2 2 2 0 HEAT repeat Aminotran_3 PF00202.21 OAJ19260.1 - 2.3e-110 369.0 0.0 2.8e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAJ19260.1 - 0.00017 20.9 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Neisseria_PilC PF05567.11 OAJ19260.1 - 0.023 13.7 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain efThoc1 PF11957.8 OAJ19261.1 - 1e-61 209.1 4.9 1.7e-56 192.0 0.0 4.1 2 1 0 2 2 2 2 THO complex subunit 1 transcription elongation factor DUF5039 PF16442.5 OAJ19261.1 - 0.053 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) NADH-u_ox-rdase PF10785.9 OAJ19262.1 - 3.1e-32 111.1 0.1 4.6e-32 110.5 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 OAJ19262.1 - 2.6e-11 43.3 0.0 4.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ubiquitin PF00240.23 OAJ19263.1 - 9.1e-33 111.8 1.5 9.8e-33 111.7 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAJ19263.1 - 8e-27 93.1 1.2 8e-27 93.1 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAJ19263.1 - 4.9e-15 55.1 0.5 8.7e-15 54.3 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ19263.1 - 4e-05 24.0 0.3 0.00093 19.6 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ19263.1 - 0.00095 19.3 0.4 0.0019 18.3 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 OAJ19263.1 - 0.014 15.6 0.3 0.026 14.8 0.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_5 PF18037.1 OAJ19263.1 - 0.014 15.7 0.6 0.026 14.9 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 OAJ19263.1 - 0.024 15.2 0.9 0.035 14.7 0.9 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 OAJ19263.1 - 0.05 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RRM_1 PF00076.22 OAJ19264.1 - 1.3e-15 57.0 0.1 2.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ19264.1 - 0.0016 18.4 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif ABC2_membrane_4 PF12730.7 OAJ19266.1 - 3.4 7.6 9.3 0.42 10.5 4.8 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Smr PF01713.21 OAJ19268.1 - 1.1e-07 32.1 0.0 6.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Smr domain ANAPC9 PF12856.7 OAJ19268.1 - 0.18 12.0 2.0 0.52 10.5 2.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 CsbD PF05532.12 OAJ19269.1 - 0.015 15.2 2.1 0.029 14.3 2.1 1.5 1 0 0 1 1 1 0 CsbD-like Fer4_15 PF13459.6 OAJ19269.1 - 0.08 13.7 0.3 0.11 13.2 0.3 1.3 1 1 0 1 1 1 0 4Fe-4S single cluster domain Arginosuc_synth PF00764.19 OAJ19270.1 - 8.8e-157 522.4 0.0 1e-156 522.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAJ19270.1 - 8.9e-05 22.1 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAJ19270.1 - 0.027 13.3 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase LolA PF03548.15 OAJ19270.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA zf-C2H2_4 PF13894.6 OAJ19271.1 - 7.7e-06 26.3 8.6 0.43 11.5 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ19271.1 - 4.5e-05 24.0 0.1 0.0045 17.6 0.0 2.5 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 OAJ19271.1 - 5.5e-05 23.4 5.9 0.3 11.2 0.0 3.0 2 1 1 3 3 3 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAJ19271.1 - 0.00066 20.0 10.5 1.3 9.7 1.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type NUDE_C PF04880.13 OAJ19271.1 - 0.27 11.7 1.9 0.49 10.9 1.9 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ribonuc_P_40 PF08584.11 OAJ19272.1 - 4.6e-42 144.2 0.0 1.2e-25 90.4 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit PPP4R2 PF09184.11 OAJ19272.1 - 0.55 9.8 10.7 0.9 9.1 10.7 1.2 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 OAJ19272.1 - 1.4 8.7 5.8 34 4.1 0.0 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 OAJ19272.1 - 1.4 7.0 12.7 2.1 6.4 12.7 1.2 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 OAJ19272.1 - 1.6 8.0 12.2 2.9 7.2 12.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 OAJ19272.1 - 5.5 5.1 15.1 8.7 4.5 15.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ19272.1 - 7.1 6.3 7.9 14 5.3 7.9 1.5 1 0 0 1 1 1 0 FAM176 family UQ_con PF00179.26 OAJ19273.1 - 5.2e-15 55.3 0.0 7.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ19273.1 - 0.0047 17.2 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain Abhydrolase_3 PF07859.13 OAJ19274.1 - 3.5e-23 82.6 0.1 4.4e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 OAJ19274.1 - 0.00042 20.3 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 Cutinase DLH PF01738.18 OAJ19274.1 - 0.00053 19.6 0.0 0.019 14.5 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAJ19274.1 - 0.029 13.8 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family zf-C2H2 PF00096.26 OAJ19275.1 - 0.00076 19.8 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ19275.1 - 0.011 16.5 0.0 0.03 15.1 0.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_13 PF18508.1 OAJ19275.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc finger domain BTP PF05232.12 OAJ19275.1 - 9.6 6.4 7.8 1 9.5 3.4 1.6 2 0 0 2 2 2 0 Chlorhexidine efflux transporter Oxidored_FMN PF00724.20 OAJ19276.1 - 3.2e-42 145.0 0.0 2.2e-33 116.0 0.0 3.1 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 OAJ19276.1 - 0.0099 15.0 0.1 0.23 10.5 0.1 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) UQ_con PF00179.26 OAJ19277.1 - 8.8e-54 181.0 0.0 9.8e-54 180.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ19277.1 - 0.0077 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ19277.1 - 0.063 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAJ19277.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain CwfJ_C_1 PF04677.15 OAJ19278.1 - 2.3e-22 79.1 0.0 5e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 OAJ19278.1 - 2.8e-13 49.4 9.4 8.9e-09 35.0 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 OAJ19278.1 - 8.5e-08 33.0 0.1 8.5e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 OAJ19278.1 - 0.079 13.1 0.7 0.22 11.6 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle SNARE_assoc PF09335.11 OAJ19279.1 - 2.1e-22 79.9 0.7 2e-21 76.7 1.1 2.5 2 1 0 2 2 2 1 SNARE associated Golgi protein AhpC-TSA_2 PF13911.6 OAJ19280.1 - 8.1e-13 48.5 0.0 5.5e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ19280.1 - 6e-08 32.5 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ19280.1 - 1.8e-07 31.1 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family NMD3 PF04981.13 OAJ19281.1 - 6.7e-81 271.3 0.5 8.7e-81 271.0 0.5 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAJ19281.1 - 0.031 14.3 8.4 0.28 11.2 5.2 2.9 1 1 1 2 2 2 0 Double zinc ribbon TT_ORF2 PF02957.15 OAJ19281.1 - 3.7 8.5 4.7 15 6.5 0.0 2.5 2 0 0 2 2 2 0 TT viral ORF2 HypA PF01155.19 OAJ19281.1 - 4.6 7.3 5.2 17 5.5 2.1 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Trypan_PARP PF05887.11 OAJ19283.1 - 7.8 6.5 8.2 0.92 9.5 2.8 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Trypan_PARP PF05887.11 OAJ19284.1 - 0.0052 16.8 10.2 0.0052 16.8 10.2 3.1 2 1 1 3 3 3 1 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 OAJ19306.1 - 4.4e-58 197.2 2.8 2.5e-27 95.7 0.4 4.0 2 2 0 3 3 3 3 Cytochrome P450 DUF973 PF06157.11 OAJ19306.1 - 0.092 11.8 1.5 0.16 11.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Ribosomal_L34 PF00468.17 OAJ19308.1 - 3.1e-19 68.6 9.6 5.3e-19 67.9 9.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 GDA1_CD39 PF01150.17 OAJ19311.1 - 6.8e-104 347.9 0.0 9.2e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF1439 PF07273.12 OAJ19311.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) CBX7_C PF17218.3 OAJ19311.1 - 2.6 7.8 4.4 5.7 6.7 4.4 1.5 1 0 0 1 1 1 0 CBX family C-terminal motif Histone PF00125.24 OAJ19312.1 - 2e-50 170.5 2.3 2.3e-50 170.4 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ19312.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ19312.1 - 0.00013 22.1 0.6 0.00019 21.5 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAJ19312.1 - 0.0004 21.0 1.4 0.00048 20.7 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 OAJ19312.1 - 0.029 14.6 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WD40 PF00400.32 OAJ19313.1 - 5.3e-25 87.2 1.8 1.7e-06 28.6 0.0 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19313.1 - 2.6e-17 62.9 1.3 9.5e-06 25.8 0.1 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ19313.1 - 2.8e-05 24.1 0.0 0.00016 21.7 0.0 2.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SNF2_N PF00176.23 OAJ19314.1 - 2.1e-41 141.8 0.0 3.7e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ19314.1 - 1.6e-16 60.6 0.0 9.1e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ19314.1 - 5e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ19314.1 - 0.00014 21.2 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase EIF_2_alpha PF07541.12 OAJ19315.1 - 1.6e-35 121.7 0.0 2.9e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAJ19315.1 - 9.6e-14 51.5 0.2 2e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 OAJ19315.1 - 0.0041 16.5 0.3 0.0056 16.0 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family AP_endonuc_2 PF01261.24 OAJ19315.1 - 0.045 13.2 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1115 PF06544.12 OAJ19317.1 - 0.0014 18.7 0.0 0.027 14.6 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Globin PF00042.22 OAJ19317.1 - 0.19 12.3 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Globin NicO PF03824.16 OAJ19318.1 - 8.7e-28 97.5 13.2 1.2e-11 44.5 0.0 5.4 4 2 1 5 5 5 4 High-affinity nickel-transport protein TRP PF06011.12 OAJ19318.1 - 0.029 13.1 2.3 0.058 12.1 2.3 1.6 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Plavaka PF18759.1 OAJ19318.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Plavaka transposase DUF3309 PF11752.8 OAJ19318.1 - 1.5 8.9 9.5 0.7 10.0 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) OPT PF03169.15 OAJ19319.1 - 7.7e-189 629.3 53.5 8.9e-189 629.1 53.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CHCH PF06747.13 OAJ19320.1 - 3e-05 24.0 0.8 4.2e-05 23.6 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 OAJ19320.1 - 0.00016 21.7 0.6 0.00019 21.4 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 OAJ19320.1 - 0.1 13.0 0.7 0.35 11.3 0.5 1.8 1 1 1 2 2 2 0 GCK domain Septin PF00735.18 OAJ19321.1 - 5.9e-115 383.4 0.7 7.9e-115 383.0 0.7 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ19321.1 - 3e-09 37.0 0.1 7.5e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ19321.1 - 1.2e-08 35.0 0.3 4.6e-07 29.9 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ19321.1 - 4.6e-07 29.6 3.4 6e-05 22.7 0.1 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 OAJ19321.1 - 3.5e-05 24.0 0.2 8.1e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ19321.1 - 5.1e-05 22.9 0.6 0.00017 21.2 0.6 1.9 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 OAJ19321.1 - 0.00045 20.7 0.9 0.00069 20.0 0.1 1.9 2 1 0 2 2 1 1 AAA ATPase domain AIG1 PF04548.16 OAJ19321.1 - 0.00047 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 OAJ19321.1 - 0.00056 20.2 1.4 0.0014 18.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAJ19321.1 - 0.0012 19.3 0.2 0.0041 17.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 OAJ19321.1 - 0.0032 17.2 1.7 0.05 13.4 0.2 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAJ19321.1 - 0.0068 15.8 0.1 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAJ19321.1 - 0.014 15.0 0.1 0.043 13.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.6 OAJ19321.1 - 0.014 15.0 0.1 0.032 13.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 OAJ19321.1 - 0.016 14.8 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 OAJ19321.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 OAJ19321.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 OAJ19321.1 - 0.025 14.4 1.2 2.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 OAJ19321.1 - 0.028 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 OAJ19321.1 - 0.034 14.2 5.0 0.59 10.2 0.2 2.8 2 1 1 3 3 3 0 Dynamin family Mg_chelatase PF01078.21 OAJ19321.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAJ19321.1 - 0.059 13.4 0.6 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ19321.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pox_A32 PF04665.12 OAJ19321.1 - 0.061 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 OAJ19321.1 - 0.078 12.6 1.7 0.46 10.1 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OAJ19321.1 - 0.094 13.1 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 OAJ19321.1 - 0.094 11.8 1.7 0.33 10.0 0.1 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein FOXP-CC PF16159.5 OAJ19321.1 - 0.11 13.2 0.5 0.4 11.3 0.5 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA_24 PF13479.6 OAJ19321.1 - 0.11 12.2 6.5 0.11 12.2 0.8 2.6 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 OAJ19321.1 - 0.14 11.1 0.3 1.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TFIIS_C PF01096.18 OAJ19322.1 - 6e-19 67.6 3.9 6e-19 67.6 3.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAJ19322.1 - 2.1e-06 27.5 0.5 2.1e-06 27.5 0.5 2.6 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 OAJ19322.1 - 6.8e-05 22.8 8.2 0.001 19.0 1.5 2.5 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 OAJ19322.1 - 0.0024 17.8 5.3 1.2 9.1 0.1 3.4 3 1 0 3 3 3 2 PhnA Zinc-Ribbon Desulfoferrod_N PF06397.12 OAJ19322.1 - 0.0067 16.0 1.6 0.047 13.3 0.2 2.3 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain zf-DNA_Pol PF08996.10 OAJ19322.1 - 0.024 14.4 1.5 0.024 14.4 1.5 1.8 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger PknG_rubred PF16919.5 OAJ19322.1 - 0.042 14.0 1.3 0.064 13.4 0.2 1.8 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain TF_Zn_Ribbon PF08271.12 OAJ19322.1 - 0.044 13.3 5.2 0.2 11.2 1.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 OAJ19322.1 - 0.049 13.5 0.7 0.049 13.5 0.7 3.2 3 0 0 3 3 3 0 Nudix N-terminal Zn_ribbon_SprT PF17283.2 OAJ19322.1 - 0.055 13.4 3.8 0.59 10.1 0.2 2.9 3 0 0 3 3 3 0 SprT-like zinc ribbon domain RNHCP PF12647.7 OAJ19322.1 - 0.057 13.4 5.8 0.62 10.1 0.1 2.4 2 1 0 2 2 2 0 RNHCP domain Auto_anti-p27 PF06677.12 OAJ19322.1 - 0.069 13.3 3.8 2 8.6 1.5 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.19 OAJ19322.1 - 0.079 13.0 3.5 6 6.9 3.5 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 OAJ19322.1 - 0.091 12.8 7.4 0.27 11.3 0.4 2.3 2 1 0 2 2 2 0 zinc-ribbons zf-FPG_IleRS PF06827.14 OAJ19322.1 - 0.1 12.5 1.8 0.1 12.5 1.8 2.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS tRNA-synt_1b PF00579.25 OAJ19322.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) zf-ribbon_3 PF13248.6 OAJ19322.1 - 0.16 11.4 6.5 5.8 6.5 0.2 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OAJ19322.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.5 2 1 1 3 3 3 0 Double zinc ribbon Rubredoxin PF00301.20 OAJ19322.1 - 0.24 11.5 6.3 2.8 8.0 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin zinc_ribbon_4 PF13717.6 OAJ19322.1 - 0.73 9.8 11.7 1.3 9.0 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 OAJ19322.1 - 4.2 7.6 9.9 7.1 6.9 0.5 2.8 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_10 PF10058.9 OAJ19322.1 - 4.8 7.0 7.2 1.4 8.7 1.2 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein APG6_N PF17675.1 OAJ19323.1 - 0.14 12.7 14.2 0.36 11.4 14.2 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 OAJ19323.1 - 2.4 8.4 7.9 13 6.1 8.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.19 OAJ19323.1 - 4.3 5.1 7.2 7.4 4.3 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MULE PF10551.9 OAJ19324.1 - 5.3e-21 74.9 0.0 1.2e-19 70.5 0.0 2.6 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 OAJ19324.1 - 8.5e-08 31.5 0.1 1.1e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 OAJ19324.1 - 0.00022 20.8 6.0 0.00089 18.9 1.2 2.6 2 0 0 2 2 2 1 SWIM zinc finger LpxB PF02684.15 OAJ19324.1 - 0.03 13.2 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase zf-CCHC PF00098.23 OAJ19324.1 - 0.093 12.8 1.5 0.22 11.7 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF1768 PF08719.11 OAJ19325.1 - 3.7e-19 69.5 0.0 6.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Calcipressin PF04847.12 OAJ19326.1 - 4.4e-24 85.3 0.0 2.2e-22 79.7 0.0 2.4 1 1 0 1 1 1 1 Calcipressin Voldacs PF03517.13 OAJ19326.1 - 6.6e-23 81.4 0.0 6.6e-23 81.4 0.0 2.1 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling DHHC PF01529.20 OAJ19327.1 - 1.2e-34 119.3 5.8 1.2e-34 119.3 5.8 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase CDC73_N PF16050.5 OAJ19327.1 - 0.41 9.9 1.2 0.67 9.2 1.2 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal Brr6_like_C_C PF10104.9 OAJ19328.1 - 4.1e-37 126.9 0.1 6.2e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain SelK_SelG PF10961.8 OAJ19328.1 - 0.098 13.3 2.7 0.37 11.4 2.7 2.0 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Glyco_hydro_92 PF07971.12 OAJ19330.1 - 7.5e-100 335.0 0.0 1e-99 334.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ19330.1 - 4.8e-27 95.4 0.4 1.4e-26 93.9 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain LtrA PF06772.11 OAJ19331.1 - 4.1e-32 111.8 32.7 9.6e-17 61.2 23.6 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Pkinase_Tyr PF07714.17 OAJ19332.1 - 8.5e-06 25.2 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ19332.1 - 0.00015 21.2 0.0 0.00072 19.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Skp1_POZ PF03931.15 OAJ19333.1 - 0.00022 21.3 0.0 0.0013 18.8 0.0 1.9 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Pkinase PF00069.25 OAJ19334.1 - 1.6e-54 185.0 0.0 2.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19334.1 - 3.8e-41 141.1 0.0 5.4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ19334.1 - 7.4e-06 25.0 1.1 8.7e-06 24.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ19334.1 - 0.02 14.8 1.3 0.09 12.7 0.8 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ19334.1 - 0.14 11.4 0.0 0.55 9.5 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAJ19334.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GCS PF03074.16 OAJ19335.1 - 4.5e-159 529.7 0.0 4.4e-158 526.4 0.0 2.0 1 1 0 1 1 1 1 Glutamate-cysteine ligase TFIIE_alpha PF02002.17 OAJ19337.1 - 1.3e-09 37.9 0.0 2.7e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit OSTMP1 PF09777.9 OAJ19337.1 - 0.087 12.2 0.3 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor ADK_lid PF05191.14 OAJ19337.1 - 0.092 12.7 1.9 0.23 11.5 1.9 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 OAJ19337.1 - 0.36 10.4 3.2 0.81 9.3 3.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding RIO1 PF01163.22 OAJ19338.1 - 9.5e-38 129.7 0.1 1.5e-25 89.9 0.0 2.6 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 OAJ19338.1 - 1.4e-29 102.2 0.0 2.9e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OAJ19338.1 - 1.3e-07 31.8 1.3 0.00011 22.3 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family BUD22 PF09073.10 OAJ19338.1 - 0.00081 18.8 31.0 0.00081 18.8 31.0 1.7 2 0 0 2 2 2 1 BUD22 Kdo PF06293.14 OAJ19338.1 - 0.0069 15.8 0.1 0.065 12.6 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_3_Rpc31 PF11705.8 OAJ19338.1 - 0.01 16.1 18.6 0.01 16.1 18.6 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 OAJ19338.1 - 3.3 7.8 34.5 6.1 6.9 12.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PROCN PF08083.11 OAJ19357.1 - 9e-225 745.9 6.9 1.5e-224 745.2 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAJ19357.1 - 9.5e-126 418.0 0.5 1.6e-125 417.3 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAJ19357.1 - 2.4e-83 277.8 1.0 3.1e-58 196.2 0.2 2.7 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAJ19357.1 - 2.1e-82 274.5 2.9 2.1e-82 274.5 2.9 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAJ19357.1 - 1.6e-65 219.2 0.0 3.5e-65 218.1 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OAJ19357.1 - 1.2e-44 150.6 0.1 2.7e-44 149.4 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OAJ19357.1 - 1.4e-40 138.0 0.0 2.9e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end_hint PF05203.16 OAJ19357.1 - 1.5e-10 41.4 0.4 4.2e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Hom_end-associated Hint Hom_end PF05204.14 OAJ19357.1 - 0.0028 17.8 0.0 0.0063 16.7 0.0 1.6 1 0 0 1 1 1 1 Homing endonuclease Peroxidase_2 PF01328.17 OAJ19358.1 - 3.4e-52 177.7 0.0 4.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 G_glu_transpept PF01019.21 OAJ19359.1 - 1.5e-143 479.3 0.2 2.4e-122 409.3 0.0 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Acid_PPase PF12689.7 OAJ19360.1 - 5.3e-54 182.6 0.0 6.2e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 OAJ19360.1 - 0.036 14.2 0.0 2.9 7.9 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ19360.1 - 0.17 12.1 0.0 0.88 9.8 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_4 PF07721.14 OAJ19360.1 - 0.74 10.6 2.3 16 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ PF00226.31 OAJ19361.1 - 3.9e-22 78.1 0.5 5.9e-22 77.6 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Hist_deacetyl PF00850.19 OAJ19362.1 - 2.5e-86 289.9 0.0 5.9e-86 288.7 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.9 OAJ19362.1 - 6.1e-30 104.2 0.1 1.7e-11 43.7 0.0 3.1 3 0 0 3 3 3 3 Arb2 domain HMG_box PF00505.19 OAJ19363.1 - 4.1e-09 36.7 0.9 8e-05 23.0 0.4 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box PF00505.19 OAJ19364.1 - 1.4e-08 35.0 0.3 0.00013 22.4 0.1 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box 6PF2K PF01591.18 OAJ19365.1 - 1.5e-63 214.1 0.2 2.7e-63 213.3 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ19365.1 - 5.1e-22 78.5 0.5 4.3e-20 72.2 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ19365.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ19365.1 - 0.0037 16.8 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 RGS PF00615.19 OAJ19367.1 - 1.4e-35 122.1 2.2 1.9e-25 89.4 0.6 3.7 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.21 OAJ19367.1 - 4e-13 49.2 0.0 1.9e-06 27.9 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) EF_assoc_1 PF08355.12 OAJ19368.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 EF hand associated BSP_II PF05432.11 OAJ19368.1 - 0.0003 20.6 2.6 0.00056 19.7 2.6 1.6 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) EF_assoc_2 PF08356.12 OAJ19368.1 - 0.053 13.5 0.1 0.091 12.8 0.1 1.3 1 0 0 1 1 1 0 EF hand associated Apt1 PF10351.9 OAJ19368.1 - 0.087 11.7 4.6 0.098 11.5 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 OAJ19368.1 - 0.24 9.1 0.8 0.28 8.9 0.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rrn6 PF10214.9 OAJ19368.1 - 1.6 7.1 8.8 2.1 6.7 8.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LRR_4 PF12799.7 OAJ19370.1 - 3.7e-09 36.7 20.2 2.3e-05 24.6 1.2 5.4 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ19370.1 - 7.6e-09 35.2 7.9 7.6e-09 35.2 7.9 4.0 7 0 0 7 7 7 1 Leucine rich repeat LRR_9 PF14580.6 OAJ19370.1 - 0.00012 21.7 0.8 0.1 12.1 0.6 3.0 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAJ19370.1 - 0.65 10.2 0.0 0.65 10.2 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich repeat HIT PF01230.23 OAJ19371.1 - 6e-22 78.2 0.2 1e-21 77.5 0.1 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 OAJ19371.1 - 2.4e-11 44.1 0.0 3.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ19371.1 - 6.3e-07 29.3 0.0 8.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.16 OAJ19372.1 - 2e-36 125.7 28.0 2e-36 125.7 28.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ19372.1 - 1e-07 31.2 21.5 3.7e-07 29.4 21.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ19372.1 - 6.7 5.5 18.8 0.024 13.5 0.7 2.7 2 1 0 3 3 3 0 MFS_1 like family DUF3808 PF10300.9 OAJ19373.1 - 1.1e-79 268.4 0.0 3.1e-79 266.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 OAJ19373.1 - 6.1e-06 26.0 0.9 0.056 13.6 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19373.1 - 4.4e-05 23.4 0.4 0.099 12.9 0.1 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19373.1 - 0.0016 19.0 0.2 3.1 8.6 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19373.1 - 0.018 15.3 3.8 4.6 7.6 0.2 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19373.1 - 0.023 14.5 1.2 1.5 8.8 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3580 PF12117.8 OAJ19373.1 - 0.069 13.4 1.0 1 9.6 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3580) TPR_16 PF13432.6 OAJ19373.1 - 0.14 12.8 0.1 6 7.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19373.1 - 0.54 10.4 1.8 16 5.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 OAJ19374.1 - 3e-28 98.9 0.0 5.6e-13 48.9 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain FHA PF00498.26 OAJ19374.1 - 1.1e-10 41.6 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.17 OAJ19374.1 - 3.5e-09 36.3 0.0 2.3e-06 27.1 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 OAJ19374.1 - 0.0021 18.3 0.0 0.0075 16.6 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 OAJ19374.1 - 0.11 12.7 0.0 0.56 10.5 0.0 2.0 2 0 0 2 2 2 0 FHA domain Kinase-like PF14531.6 OAJ19374.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FHA PF00498.26 OAJ19375.1 - 0.0001 22.6 0.0 0.00024 21.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain SVIP PF15811.5 OAJ19375.1 - 0.1 13.0 0.2 0.3 11.6 0.2 1.8 1 0 0 1 1 1 0 Small VCP/p97-interacting protein BSP_II PF05432.11 OAJ19376.1 - 8.4 6.0 17.3 0.21 11.2 1.5 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ECH_1 PF00378.20 OAJ19377.1 - 2.8e-39 134.9 6.2 4.6e-20 72.0 0.6 4.0 2 2 2 4 4 4 4 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ19377.1 - 8.7e-21 74.8 3.3 6.3e-20 71.9 0.7 2.8 2 2 0 2 2 2 1 Enoyl-CoA hydratase/isomerase LSM PF01423.22 OAJ19378.1 - 2.6e-16 59.1 0.1 3.1e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OAJ19378.1 - 0.048 13.8 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF2370 PF10176.9 OAJ19379.1 - 5.8e-71 238.7 0.0 1.8e-70 237.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF3611 PF12263.8 OAJ19379.1 - 0.059 13.3 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF202 PF02656.15 OAJ19379.1 - 6.9 7.2 7.8 0.46 10.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Actin PF00022.19 OAJ19380.1 - 6.4e-27 94.2 0.0 7.4e-17 61.0 0.0 3.8 3 1 0 3 3 3 2 Actin HK PF02110.15 OAJ19381.1 - 1e-62 211.7 1.8 8e-59 199.0 1.9 2.5 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAJ19381.1 - 5.2e-44 149.7 0.3 2.2e-43 147.7 0.2 2.0 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 OAJ19381.1 - 2.6e-07 30.3 0.4 4.6e-07 29.5 0.4 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mito_carr PF00153.27 OAJ19382.1 - 2.8e-59 197.1 3.9 2.2e-20 72.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_6 PF15985.5 OAJ19383.1 - 6.1e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 OAJ19383.1 - 2.8e-06 27.1 1.9 3.2e-05 23.8 0.6 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain DPBB_1 PF03330.18 OAJ19385.1 - 4.6e-10 39.6 0.4 1.2e-09 38.3 0.4 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ19385.1 - 0.00079 19.3 0.3 0.0015 18.4 0.3 1.4 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 OAJ19385.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Cerato-platanin SDA1 PF05285.12 OAJ19385.1 - 0.33 10.3 8.7 0.41 10.0 8.7 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ19385.1 - 1.3 7.2 12.5 1.5 6.9 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 OAJ19385.1 - 3.7 7.0 11.6 5 6.6 11.6 1.2 1 0 0 1 1 1 0 PPP4R2 Prenyltrans PF00432.21 OAJ19402.1 - 1.9e-36 123.5 9.2 3.8e-12 45.7 0.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat LUC7 PF03194.15 OAJ19403.1 - 1.1e-70 238.2 3.6 1.7e-70 237.6 3.6 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Proteasome PF00227.26 OAJ19404.1 - 4.9e-48 163.1 0.1 6.2e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.9 OAJ19404.1 - 0.0075 16.4 0.2 0.67 10.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2188) Phos_pyr_kin PF08543.12 OAJ19405.1 - 3.7e-09 36.3 0.0 7.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAJ19405.1 - 1.6e-05 24.3 0.2 4.7e-05 22.8 0.0 1.8 2 1 1 3 3 3 1 pfkB family carbohydrate kinase Sterol-sensing PF12349.8 OAJ19406.1 - 2.4e-42 144.3 12.1 4.7e-42 143.4 12.1 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ19406.1 - 1.2e-12 46.8 3.4 1.8e-12 46.2 3.4 1.1 1 0 0 1 1 1 1 Patched family 6PGD PF00393.19 OAJ19407.1 - 4.7e-127 423.3 0.0 5.8e-127 423.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAJ19407.1 - 1.7e-51 174.5 0.0 2.5e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ19407.1 - 0.024 14.9 0.0 0.12 12.7 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 OAJ19407.1 - 0.036 14.7 0.1 0.067 13.8 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CoatB PF10389.9 OAJ19407.1 - 0.13 12.1 1.4 0.61 10.0 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B RQC PF09382.10 OAJ19409.1 - 1.3e-22 79.7 0.1 6.7e-22 77.4 0.0 2.1 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.31 OAJ19409.1 - 9.5e-19 67.8 0.0 2e-17 63.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ19409.1 - 1.8e-18 66.9 0.0 3.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 OAJ19409.1 - 2.1e-17 63.6 3.4 5.8e-17 62.2 3.4 1.8 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 OAJ19409.1 - 1.7e-11 44.0 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.8 OAJ19409.1 - 0.041 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase Nup188 PF10487.9 OAJ19410.1 - 3.1e-22 78.4 0.2 2.1e-10 39.2 0.1 2.5 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 MFS_1 PF07690.16 OAJ19411.1 - 1.7e-28 99.6 27.7 1.7e-28 99.6 27.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ19411.1 - 3.8e-22 78.8 16.4 7.4e-18 64.6 4.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ19411.1 - 0.00085 18.3 5.4 0.0012 17.8 0.4 2.6 2 1 0 3 3 3 1 MFS_1 like family OTU PF02338.19 OAJ19412.1 - 5.7e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Zn_ribbon_recom PF13408.6 OAJ19412.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_2 PF12756.7 OAJ19412.1 - 0.2 12.0 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) COesterase PF00135.28 OAJ19413.1 - 1.5e-73 248.4 0.0 1.9e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ19413.1 - 9.8e-07 28.8 1.8 7e-05 22.8 0.4 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Invasin_D3 PF09134.10 OAJ19413.1 - 0.019 15.3 1.0 0.062 13.6 1.0 1.9 1 0 0 1 1 1 0 Invasin, domain 3 Vps53_N PF04100.12 OAJ19415.1 - 3.3e-84 283.1 0.4 5.5e-84 282.3 0.4 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 OAJ19415.1 - 0.00043 20.2 0.0 0.0079 16.1 0.0 2.3 1 1 1 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 OAJ19415.1 - 0.015 14.6 4.8 0.029 13.7 4.8 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex RecG_N PF17190.4 OAJ19415.1 - 0.1 13.3 0.8 0.37 11.6 0.8 2.0 1 0 0 1 1 1 0 RecG N-terminal helical domain Sec5 PF15469.6 OAJ19415.1 - 0.2 11.4 1.6 0.47 10.2 1.6 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 Fib_alpha PF08702.10 OAJ19415.1 - 4.1 7.6 4.7 9.4 6.4 3.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 OAJ19417.1 - 0.083 11.8 17.2 0.078 11.8 15.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAJ19417.1 - 0.6 10.2 13.1 0.31 11.1 10.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus VIR_N PF15912.5 OAJ19417.1 - 6.2 6.3 13.7 1.2 8.7 0.8 3.2 1 1 1 2 2 2 0 Virilizer, N-terminal TFIIA PF03153.13 OAJ19418.1 - 0.00052 20.1 9.1 0.00052 20.1 9.1 1.9 1 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 OAJ19418.1 - 0.064 13.7 5.3 0.17 12.4 5.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1754 PF08555.10 OAJ19418.1 - 3.1 8.7 10.4 1.5 9.7 3.9 2.8 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) RPN2_C PF18004.1 OAJ19418.1 - 5.2 7.0 7.3 1.4 8.8 2.4 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cpn60_TCP1 PF00118.24 OAJ19419.1 - 7.5e-149 496.5 12.5 8.9e-149 496.2 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 OAJ19419.1 - 0.00042 19.9 0.1 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination SNF2_N PF00176.23 OAJ19420.1 - 1.2e-68 231.4 0.1 2.4e-68 230.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ19420.1 - 4.6e-21 75.2 0.3 1.1e-19 70.8 0.0 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 OAJ19420.1 - 1.4e-20 73.4 10.9 1.4e-20 73.4 10.9 3.0 2 0 0 2 2 2 1 HSA Bromodomain PF00439.25 OAJ19420.1 - 1.9e-16 59.9 0.2 4.5e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 OAJ19420.1 - 2.2e-12 47.4 1.5 2.2e-12 47.4 1.5 3.4 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 OAJ19420.1 - 3e-11 42.9 4.4 7.1e-11 41.7 4.4 1.7 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 OAJ19420.1 - 1.2e-09 38.5 0.0 2.3e-08 34.2 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 OAJ19420.1 - 0.00039 20.2 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF3755 PF12579.8 OAJ19420.1 - 0.15 11.7 1.2 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) AA_kinase PF00696.28 OAJ19421.1 - 1e-35 123.5 0.0 1.3e-29 103.5 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.25 OAJ19421.1 - 8.3e-08 31.9 0.2 0.015 15.0 0.0 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OAJ19421.1 - 3.7e-06 26.6 1.5 7.8e-06 25.6 0.2 2.2 2 0 0 2 2 2 1 ACT domain Thiamine_BP PF01910.17 OAJ19422.1 - 9e-21 73.6 0.0 1.7e-20 72.7 0.0 1.4 2 0 0 2 2 2 1 Thiamine-binding protein Ykof PF07615.11 OAJ19422.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family DUF4965 PF16335.5 OAJ19423.1 - 7.4e-67 224.3 0.1 1.3e-66 223.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAJ19423.1 - 1.1e-64 217.9 0.5 2e-64 217.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAJ19423.1 - 2.7e-48 164.7 1.1 5.4e-48 163.7 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ19423.1 - 3.8e-05 23.2 1.9 0.046 13.3 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ19423.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Ribosomal_S9 PF00380.19 OAJ19424.1 - 9.5e-44 148.8 0.3 2.5e-43 147.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 His_Phos_2 PF00328.22 OAJ19425.1 - 4.5e-73 246.8 0.1 6.2e-73 246.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAJ19425.1 - 7.7e-35 118.9 0.1 1.7e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAJ19425.1 - 9.5e-06 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF190 PF02641.15 OAJ19425.1 - 0.14 12.5 0.0 34 4.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized ACR, COG1993 FLYWCH_u PF16662.5 OAJ19426.1 - 0.011 15.8 0.9 0.019 15.0 0.9 1.3 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 Myc_N PF01056.18 OAJ19426.1 - 0.061 13.2 3.8 0.062 13.2 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Hist_deacetyl PF00850.19 OAJ19427.1 - 1.1e-81 274.6 0.0 1.5e-81 274.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ArgJ PF01960.18 OAJ19428.1 - 4e-130 433.9 0.1 6e-130 433.3 0.1 1.2 1 0 0 1 1 1 1 ArgJ family Abhydrolase_1 PF00561.20 OAJ19429.1 - 3.6e-38 131.7 0.0 4.2e-37 128.2 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAJ19429.1 - 0.0003 20.5 0.1 0.0005 19.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 OAJ19429.1 - 0.16 11.2 0.1 2.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GMC_oxred_N PF00732.19 OAJ19443.1 - 3.4e-50 171.1 0.0 4.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ19443.1 - 1.5e-35 122.9 0.0 2.4e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ19443.1 - 1.6e-05 24.2 0.0 0.00011 21.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ19443.1 - 3.1e-05 23.4 0.3 0.006 15.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ19443.1 - 0.00015 20.9 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAJ19443.1 - 0.00018 21.2 0.1 0.0018 17.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ19443.1 - 0.00028 21.0 0.1 0.00074 19.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ19443.1 - 0.0034 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ19443.1 - 0.007 15.6 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPR_17 PF13431.6 OAJ19444.1 - 3.2e-07 30.3 0.5 0.0088 16.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19444.1 - 8.7e-07 29.5 27.1 0.0028 18.3 1.6 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19444.1 - 2e-06 27.5 2.3 0.091 13.0 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19444.1 - 3.2e-06 26.8 10.5 0.13 12.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19444.1 - 2.2e-05 24.6 2.7 0.0033 17.6 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAJ19444.1 - 0.0013 18.5 0.5 2.3 8.2 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19444.1 - 0.011 16.5 33.0 0.038 14.8 1.4 8.6 6 2 3 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19444.1 - 0.059 13.9 0.2 0.059 13.9 0.2 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 OAJ19444.1 - 0.2 10.7 4.2 1.4 7.8 0.3 2.5 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 OAJ19444.1 - 1.7 8.9 23.1 1.9 8.7 2.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RNase_PH PF01138.21 OAJ19445.1 - 4.2e-28 98.5 0.0 6.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_P_Rpp14 PF01900.19 OAJ19446.1 - 1.5e-26 92.6 0.0 2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family NT-C2 PF10358.9 OAJ19447.1 - 8.7e-10 38.5 3.1 0.00049 19.8 0.0 4.4 4 0 0 4 4 4 4 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L6 PF00347.23 OAJ19448.1 - 1.4e-17 64.1 0.0 2.7e-10 40.8 0.0 3.8 4 0 0 4 4 4 3 Ribosomal protein L6 Ribosomal_60s PF00428.19 OAJ19448.1 - 0.4 11.3 4.7 0.96 10.1 4.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Arf PF00025.21 OAJ19449.1 - 2.4e-68 229.0 0.0 2.8e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ19449.1 - 2.1e-12 46.9 1.5 7.2e-07 28.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAJ19449.1 - 9.6e-12 45.2 0.1 1.9e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ19449.1 - 9.3e-10 38.2 0.0 1.2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ19449.1 - 2.5e-07 30.3 0.0 3.2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAJ19449.1 - 9.4e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAJ19449.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAJ19449.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OAJ19449.1 - 0.064 12.8 0.0 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 OAJ19449.1 - 0.21 11.3 0.1 0.27 10.9 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Ribosomal_L28 PF00830.19 OAJ19450.1 - 2.8e-20 72.3 0.5 5.2e-20 71.4 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L28 family COQ7 PF03232.13 OAJ19450.1 - 0.0013 18.6 0.1 0.89 9.3 0.0 2.1 1 1 1 2 2 2 2 Ubiquinone biosynthesis protein COQ7 CsgG PF03783.14 OAJ19450.1 - 0.052 12.8 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Brix PF04427.18 OAJ19451.1 - 6.2e-31 108.0 0.1 8.2e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 OAJ19451.1 - 0.016 14.9 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) DUF4128 PF13554.6 OAJ19451.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function DUF1690 PF07956.11 OAJ19452.1 - 1.7e-25 90.1 11.4 1.7e-25 90.1 11.4 2.1 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) Tcp11 PF05794.13 OAJ19452.1 - 0.0042 16.3 5.9 0.0061 15.7 5.9 1.3 1 0 0 1 1 1 1 T-complex protein 11 Rootletin PF15035.6 OAJ19452.1 - 0.47 10.5 11.6 4.6 7.2 11.5 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF883 PF05957.13 OAJ19452.1 - 0.75 10.4 19.7 1.3 9.7 2.3 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Peptidase_S64 PF08192.11 OAJ19452.1 - 1.3 7.4 15.4 1.5 7.2 15.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 Erp_C PF06780.11 OAJ19452.1 - 1.5 8.9 10.7 2.5 8.1 4.8 2.2 2 0 0 2 2 2 0 Erp protein C-terminus Allexi_40kDa PF05549.11 OAJ19452.1 - 2.3 7.7 6.3 12 5.3 1.0 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Occludin_ELL PF07303.13 OAJ19452.1 - 2.8 8.7 7.3 0.72 10.6 0.5 2.8 2 1 1 3 3 3 0 Occludin homology domain YabA PF06156.13 OAJ19452.1 - 6 7.6 7.1 83 3.9 4.5 3.0 2 1 0 2 2 2 0 Initiation control protein YabA SPA PF08616.10 OAJ19453.1 - 1e-35 122.1 0.0 2.2e-35 121.1 0.0 1.6 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 OAJ19453.1 - 9.9e-25 87.6 0.0 2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAJ19453.1 - 4.7e-09 35.4 0.0 0.00029 19.7 0.0 3.5 2 2 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 OAJ19453.1 - 0.0089 15.6 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) FTR1 PF03239.14 OAJ19454.1 - 6.4e-55 186.5 8.1 2.3e-35 122.2 4.4 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.16 OAJ19454.1 - 0.066 12.1 0.7 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Cu-oxidase_2 PF07731.14 OAJ19455.1 - 9.2e-38 129.1 8.1 9.9e-37 125.7 3.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAJ19455.1 - 5.1e-37 127.4 0.2 1.5e-31 109.6 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAJ19455.1 - 9.5e-27 93.4 8.1 2.9e-26 91.8 2.3 3.5 4 0 0 4 4 4 1 Multicopper oxidase Per1 PF04080.13 OAJ19456.1 - 2.3e-92 309.3 0.0 3.5e-92 308.8 0.0 1.3 1 0 0 1 1 1 1 Per1-like family Meleagrin PF08189.11 OAJ19456.1 - 0.44 10.3 1.9 0.98 9.2 1.9 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family BRE1 PF08647.11 OAJ19457.1 - 3.9e-20 71.7 12.6 3.9e-20 71.7 12.6 7.4 5 3 2 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 OAJ19457.1 - 2e-06 27.5 9.7 4.1e-06 26.5 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ19457.1 - 3.7e-06 26.7 13.6 6.5e-06 25.9 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ19457.1 - 1.7e-05 24.7 12.4 4.1e-05 23.4 12.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ19457.1 - 1.9e-05 24.6 6.5 3.6e-05 23.7 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ19457.1 - 2.5e-05 24.0 11.4 4.3e-05 23.3 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ19457.1 - 5.7e-05 22.9 2.8 0.00012 21.9 2.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 OAJ19457.1 - 0.00054 20.2 10.6 0.00091 19.5 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain Fez1 PF06818.15 OAJ19457.1 - 0.0021 18.6 18.1 0.0021 18.6 18.1 5.2 4 1 1 5 5 4 2 Fez1 zf-rbx1 PF12678.7 OAJ19457.1 - 0.0052 17.0 6.7 0.012 15.9 6.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ19457.1 - 0.0073 16.1 8.5 0.014 15.3 8.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ19457.1 - 0.018 15.2 8.2 0.033 14.3 8.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.6 OAJ19457.1 - 0.019 14.3 2.3 0.05 13.0 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1272 PF06906.11 OAJ19457.1 - 0.088 12.9 4.5 0.23 11.6 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 OAJ19457.1 - 0.8 9.6 4.6 2.1 8.2 4.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 OAJ19457.1 - 1.1 9.3 3.8 2.1 8.5 3.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FlaC_arch PF05377.11 OAJ19457.1 - 3.3 8.2 21.4 11 6.5 0.4 7.0 6 3 3 9 9 8 0 Flagella accessory protein C (FlaC) DZR PF12773.7 OAJ19457.1 - 3.6 7.7 9.9 1.3 9.1 6.8 1.9 2 0 0 2 2 2 0 Double zinc ribbon Nsp1_C PF05064.13 OAJ19457.1 - 8.4 6.2 21.7 3.6 7.4 4.3 5.1 2 2 3 5 5 5 0 Nsp1-like C-terminal region TP_methylase PF00590.20 OAJ19458.1 - 2.3e-15 57.1 0.7 5.4e-15 55.9 0.1 1.9 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Cellulase PF00150.18 OAJ19459.1 - 3.7e-12 46.3 0.2 5.5e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.22 OAJ19460.1 - 3.2e-32 112.0 9.2 7.1e-32 110.9 9.2 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAJ19460.1 - 1e-11 45.3 0.2 2.2e-11 44.3 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 MIG-14_Wnt-bd PF06664.12 OAJ19461.1 - 0.00078 18.8 8.1 0.01 15.1 3.0 2.3 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion Cyt_bd_oxida_II PF02322.15 OAJ19461.1 - 0.0051 16.2 7.2 0.0051 16.2 7.2 2.1 1 1 1 2 2 2 1 Cytochrome bd terminal oxidase subunit II DUF3180 PF11377.8 OAJ19461.1 - 0.58 10.3 7.6 0.07 13.3 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) DUF202 PF02656.15 OAJ19461.1 - 0.76 10.3 12.9 5.8 7.4 2.7 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF202) NnrS PF05940.12 OAJ19461.1 - 1.4 8.2 13.1 5.4 6.3 0.3 2.1 1 1 0 2 2 2 0 NnrS protein Abhydrolase_9_N PF15420.6 OAJ19461.1 - 2.6 8.0 9.5 12 5.8 6.1 2.5 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4064 PF13273.6 OAJ19461.1 - 2.9 8.2 11.1 2.3 8.5 1.7 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) CHRD PF07452.12 OAJ19462.1 - 3e-30 105.5 2.1 4.2e-14 53.5 0.2 2.3 2 0 0 2 2 2 2 CHRD domain WD40_like PF17005.5 OAJ19462.1 - 0.21 10.9 0.0 11 5.3 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Aminotran_1_2 PF00155.21 OAJ19463.1 - 2.8e-43 148.5 0.0 3.4e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ19463.1 - 1.5e-05 24.2 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ19463.1 - 3.9e-05 22.4 0.0 5.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Vps51 PF08700.11 OAJ19465.1 - 1e-20 73.6 0.0 1.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 OAJ19465.1 - 0.00018 20.3 0.1 0.00023 20.0 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 OAJ19465.1 - 0.0023 18.1 0.1 0.0034 17.6 0.1 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 SKA2 PF16740.5 OAJ19465.1 - 0.0048 16.7 0.1 0.0081 15.9 0.0 1.4 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Vps52 PF04129.12 OAJ19465.1 - 0.04 12.7 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family NPC1_N PF16414.5 OAJ19466.1 - 2.9e-65 220.3 14.5 6e-65 219.2 6.4 2.9 2 1 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAJ19466.1 - 5.4e-62 210.0 4.8 1.7e-37 129.0 0.2 3.1 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 OAJ19466.1 - 3.8e-45 153.5 8.3 4.1e-23 81.9 0.2 3.1 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OAJ19466.1 - 0.0027 15.4 3.9 0.004 14.9 3.9 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 OAJ19466.1 - 0.041 13.8 0.4 0.096 12.5 0.4 1.5 1 0 0 1 1 1 0 Folate receptor family F-box PF00646.33 OAJ19467.1 - 3.6e-06 26.7 0.4 6.4e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ19467.1 - 0.00064 19.6 0.7 0.001 18.9 0.7 1.3 1 0 0 1 1 1 1 F-box-like DUF1472 PF07339.12 OAJ19467.1 - 0.1 13.1 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1472) Asp_protease_2 PF13650.6 OAJ19469.1 - 0.00037 21.1 0.1 0.0016 19.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease Peptidase_C50 PF03568.17 OAJ19470.1 - 4.5e-113 378.4 0.0 6.3e-113 377.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_8 PF13181.6 OAJ19470.1 - 0.00038 20.4 0.1 0.2 12.0 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19470.1 - 0.0034 17.3 0.2 9.1 6.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19470.1 - 0.0043 17.0 2.9 8.6 6.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19470.1 - 0.0065 16.2 0.0 4.8 7.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19470.1 - 0.37 11.1 14.5 1.7 9.0 1.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19470.1 - 0.98 10.0 5.3 1 9.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 OAJ19471.1 - 2.3e-48 164.1 2.2 5.4e-48 162.9 2.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ19471.1 - 2e-29 103.4 1.1 3.5e-23 83.0 0.1 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAJ19471.1 - 8.9e-21 74.1 0.0 9.2e-13 48.4 0.0 3.0 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.7 OAJ19471.1 - 0.0039 17.6 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ19471.1 - 0.0069 16.2 1.5 0.064 13.0 1.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RsgA_GTPase PF03193.16 OAJ19471.1 - 0.14 12.1 0.0 0.41 10.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase DUF4006 PF13179.6 OAJ19471.1 - 0.15 11.9 2.0 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF4006) RSN1_7TM PF02714.15 OAJ19490.1 - 1.4e-68 231.2 24.9 2.5e-68 230.3 24.9 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ19490.1 - 9.7e-37 126.9 0.0 1.6e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ19490.1 - 1.3e-36 125.8 0.9 1.3e-36 125.8 0.9 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Asp PF00026.23 OAJ19493.1 - 1.8e-18 67.1 0.0 3.1e-18 66.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ19493.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal Rad21_Rec8_N PF04825.13 OAJ19495.1 - 4.6e-25 87.9 0.0 9.9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ19495.1 - 1.4e-09 37.1 0.0 3.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SUIM_assoc PF16619.5 OAJ19495.1 - 0.018 15.1 0.5 0.061 13.4 0.5 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3391 PF11871.8 OAJ19495.1 - 7.5 7.1 7.3 1.9 9.0 3.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF2236 PF09995.9 OAJ19496.1 - 8.6e-16 58.8 0.8 1.7e-15 57.9 0.8 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AbiEii PF08843.11 OAJ19497.1 - 0.062 13.3 0.0 5.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Fe_hyd_lg_C PF02906.14 OAJ19498.1 - 1.1e-54 185.7 0.0 4.3e-54 183.8 0.0 2.0 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain S4 PF01479.25 OAJ19499.1 - 6.7e-12 44.9 0.0 1.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OAJ19499.1 - 1.2e-09 38.9 0.2 1.8e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Creatinase_N_2 PF16189.5 OAJ19500.1 - 9.7e-45 152.6 0.0 4.4e-44 150.4 0.0 2.0 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAJ19500.1 - 6e-42 143.7 0.0 8.3e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OAJ19500.1 - 3.4e-20 71.9 0.0 2.4e-18 65.9 0.0 2.8 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OAJ19500.1 - 7.6e-17 62.2 0.0 3.6e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAJ19501.1 - 1.4e-51 175.2 0.0 2.1e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAJ19501.1 - 4.4e-39 133.0 0.0 8.9e-39 132.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 OAJ19501.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) MFS_1 PF07690.16 OAJ19502.1 - 1.1e-38 133.2 41.4 1.4e-35 122.9 42.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 OAJ19502.1 - 0.98 9.2 4.7 3.8 7.3 3.7 2.4 2 0 0 2 2 2 0 Fatty acid desaturase Xan_ur_permease PF00860.20 OAJ19503.1 - 6.9e-49 166.6 32.1 2.3e-47 161.5 32.1 2.1 1 1 0 1 1 1 1 Permease family HIG_1_N PF04588.13 OAJ19504.1 - 1.2e-05 25.4 0.6 2.4e-05 24.4 0.6 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TctA PF01970.16 OAJ19504.1 - 0.033 12.9 0.2 0.054 12.2 0.2 1.3 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family ENOD93 PF03386.14 OAJ19504.1 - 0.048 13.5 1.0 0.14 12.0 0.2 2.1 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein AA_permease_2 PF13520.6 OAJ19505.1 - 9.1e-53 179.6 54.9 1.1e-52 179.4 54.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ19505.1 - 2e-06 26.7 51.9 8e-06 24.7 52.0 1.9 1 1 0 1 1 1 1 Amino acid permease TraQ PF09679.10 OAJ19505.1 - 0.0087 16.0 0.0 0.045 13.7 0.0 2.3 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) RNA_pol_A_bac PF01000.26 OAJ19506.1 - 1e-26 93.5 0.0 2.6e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ19506.1 - 1e-22 79.3 0.0 1.3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 OAJ19506.1 - 0.017 14.8 0.2 0.07 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF22 ERCC3_RAD25_C PF16203.5 OAJ19507.1 - 3.4e-123 409.7 0.0 5.8e-123 408.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAJ19507.1 - 2.2e-35 121.5 0.0 5.3e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ19507.1 - 3.5e-17 62.9 0.0 5.7e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ19507.1 - 3e-10 40.4 0.1 7.6e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAJ19507.1 - 3.3e-08 32.6 0.0 4.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 OAJ19507.1 - 0.00012 21.9 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cyclin_N PF00134.23 OAJ19508.1 - 1.9e-11 43.8 0.3 4e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ19508.1 - 0.00034 20.6 0.4 0.00082 19.4 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 OAJ19508.1 - 0.0028 18.0 0.5 0.0087 16.4 0.5 1.9 1 1 0 1 1 1 1 Cyclin C-terminal domain SOG2 PF10428.9 OAJ19508.1 - 3.2 6.8 12.5 4.3 6.4 12.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3341 PF11821.8 OAJ19509.1 - 0.0049 16.5 0.9 2.6 7.7 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3341) DUF4636 PF15468.6 OAJ19509.1 - 0.038 13.7 0.2 0.12 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) DUF4713 PF15831.5 OAJ19509.1 - 0.077 13.5 3.2 0.45 11.0 3.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) TcpE PF12648.7 OAJ19509.1 - 2.6 8.6 7.6 3.2 8.3 0.7 2.7 2 0 0 2 2 2 0 TcpE family Amastin PF07344.11 OAJ19509.1 - 6.2 6.6 7.1 1.7 8.5 1.3 2.7 3 0 0 3 3 3 0 Amastin surface glycoprotein Retrotran_gag_2 PF14223.6 OAJ19512.1 - 2.2e-06 27.4 0.1 5.5e-05 22.9 0.2 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ19512.1 - 5.1e-05 23.5 0.4 0.023 15.0 0.1 2.5 2 0 0 2 2 2 2 Retrotransposon gag protein DUF4817 PF16087.5 OAJ19512.1 - 0.056 13.2 0.9 0.87 9.4 0.2 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) SEP PF08059.13 OAJ19512.1 - 0.079 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 SEP domain Asp PF00026.23 OAJ19514.1 - 6.7e-19 68.4 0.0 1e-18 67.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AAA_5 PF07728.14 OAJ19515.1 - 3.5e-59 198.8 0.0 1.2e-25 90.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ19515.1 - 0.0083 16.5 0.6 0.43 11.0 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ19515.1 - 0.09 13.0 0.0 0.36 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain HI0933_like PF03486.14 OAJ19515.1 - 0.14 10.8 2.1 0.25 10.0 2.1 1.3 1 0 0 1 1 1 0 HI0933-like protein SNAP PF14938.6 OAJ19533.1 - 1.1e-93 313.8 13.8 1.2e-93 313.6 13.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 OAJ19533.1 - 0.0021 18.1 3.6 0.91 9.7 0.1 3.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19533.1 - 0.0074 16.9 2.5 0.0074 16.9 2.5 5.1 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19533.1 - 0.0098 16.5 18.2 2.6 8.8 0.2 6.6 4 2 0 5 5 5 2 Tetratricopeptide repeat Spatacsin_C PF14649.6 OAJ19533.1 - 0.017 14.2 4.2 0.27 10.3 1.3 2.2 1 1 1 2 2 2 0 Spatacsin C-terminus DUF4170 PF13773.6 OAJ19533.1 - 0.092 12.9 1.1 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) TPR_7 PF13176.6 OAJ19533.1 - 0.096 12.8 9.0 4.5 7.5 0.1 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 OAJ19533.1 - 0.12 12.9 1.1 0.38 11.3 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) PerC PF06069.11 OAJ19533.1 - 0.14 12.5 1.5 6.2 7.1 0.2 2.7 2 1 0 2 2 2 0 PerC transcriptional activator TPR_2 PF07719.17 OAJ19533.1 - 0.51 10.6 18.6 6.8 7.1 0.1 6.9 3 3 5 8 8 8 0 Tetratricopeptide repeat Bud13 PF09736.9 OAJ19534.1 - 1.2e-47 162.0 6.6 1.2e-47 162.0 6.6 2.4 2 1 0 2 2 2 2 Pre-mRNA-splicing factor of RES complex DUF3350 PF11830.8 OAJ19534.1 - 0.23 11.8 5.2 2.6 8.4 2.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) RRM_1 PF00076.22 OAJ19535.1 - 8.9e-45 150.4 0.0 3.8e-22 77.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ19535.1 - 4.2e-09 36.1 0.0 0.00017 21.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ19535.1 - 1e-07 32.0 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAJ19535.1 - 0.00013 22.0 0.0 0.091 12.8 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 OAJ19535.1 - 0.025 14.4 0.0 8.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAJ19535.1 - 0.043 13.8 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GFA PF04828.14 OAJ19536.1 - 9.2e-08 32.3 0.6 0.00019 21.7 0.1 3.0 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme TMCCDC2 PF15844.5 OAJ19536.1 - 0.22 11.5 1.2 0.34 10.8 1.2 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DUF2316 PF10078.9 OAJ19538.1 - 0.066 13.5 0.0 0.23 11.7 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HMG_box PF00505.19 OAJ19539.1 - 2.5e-05 24.6 0.3 2.5e-05 24.6 0.3 4.9 4 1 0 4 4 4 2 HMG (high mobility group) box FmdA_AmdA PF03069.15 OAJ19540.1 - 0.036 12.9 1.4 0.07 12.0 1.4 1.6 1 1 0 1 1 1 0 Acetamidase/Formamidase family CCDC92 PF14916.6 OAJ19540.1 - 0.16 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function OPT PF03169.15 OAJ19541.1 - 1.1e-145 486.8 32.9 1.2e-145 486.6 32.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Thioredoxin PF00085.20 OAJ19542.1 - 1.4e-37 127.8 0.0 4.8e-25 87.5 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 OAJ19542.1 - 1.6e-13 51.0 0.0 0.0019 18.1 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAJ19542.1 - 1.2e-05 25.3 0.1 0.00035 20.6 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 OAJ19542.1 - 0.00014 22.3 0.1 0.023 15.2 0.1 3.4 3 1 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ19542.1 - 0.00096 19.1 0.1 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ19542.1 - 0.0055 17.0 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OAJ19542.1 - 0.014 15.1 0.1 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 Redoxin GARS_C PF02843.16 OAJ19542.1 - 0.032 14.5 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain TraF PF13728.6 OAJ19542.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 OAJ19542.1 - 0.13 12.1 0.1 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin Spt5_N PF11942.8 OAJ19543.1 - 9.5e-20 71.4 11.3 9.5e-20 71.4 11.3 3.1 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 OAJ19543.1 - 1.2e-17 63.5 0.0 2.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OAJ19543.1 - 5.8e-11 41.9 15.6 8.2e-06 25.6 0.4 5.2 6 0 0 6 6 6 3 KOW motif CTD PF12815.7 OAJ19543.1 - 0.39 11.3 53.5 0.086 13.4 8.3 4.8 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Utp14 PF04615.13 OAJ19543.1 - 1.4 7.4 22.4 2 6.9 22.4 1.1 1 0 0 1 1 1 0 Utp14 protein YL1 PF05764.13 OAJ19543.1 - 1.9 8.5 21.5 3.2 7.8 21.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.9 OAJ19543.1 - 4.8 6.2 32.9 9.8 5.2 32.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ank_2 PF12796.7 OAJ19544.1 - 7.6e-52 173.8 0.0 4.3e-19 68.9 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ19544.1 - 6.3e-36 122.0 1.0 4.3e-12 46.0 0.0 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ19544.1 - 7.1e-32 109.4 2.0 4.9e-11 42.9 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ19544.1 - 2.3e-23 79.7 1.3 2.4e-05 24.4 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 OAJ19544.1 - 6.7e-21 73.8 0.0 0.00068 20.0 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 OAJ19544.1 - 4.1e-18 65.3 8.7 4.1e-18 65.3 8.7 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 OAJ19544.1 - 3.5e-08 33.6 3.3 3.5e-08 33.6 3.3 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OAJ19544.1 - 6e-05 22.7 4.6 0.00016 21.4 4.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ19544.1 - 0.00037 20.3 2.7 0.00037 20.3 2.7 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ19544.1 - 0.01 16.1 2.5 0.01 16.1 2.5 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAJ19544.1 - 0.013 15.5 3.3 0.013 15.5 3.3 2.7 3 0 0 3 3 1 0 RING-type zinc-finger CMS1 PF14617.6 OAJ19544.1 - 0.091 12.1 0.0 0.7 9.2 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FYVE_2 PF02318.16 OAJ19544.1 - 0.24 11.6 7.0 0.1 12.8 2.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger FANCL_C PF11793.8 OAJ19544.1 - 2.5 8.3 6.0 1.2 9.4 2.7 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain BUD22 PF09073.10 OAJ19545.1 - 0.0024 17.3 10.1 0.0024 17.3 10.1 2.5 3 0 0 3 3 3 1 BUD22 SAPS PF04499.15 OAJ19545.1 - 0.0047 15.8 4.5 0.0047 15.8 4.5 1.5 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein HeLo PF14479.6 OAJ19545.1 - 0.3 10.9 8.1 0.08 12.8 4.5 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation Nop14 PF04147.12 OAJ19545.1 - 0.69 8.1 20.4 1 7.5 20.4 1.2 1 0 0 1 1 1 0 Nop14-like family Membralin PF09746.9 OAJ19545.1 - 1.2 8.1 4.9 2.2 7.2 4.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein SDA1 PF05285.12 OAJ19545.1 - 4.1 6.8 22.6 6.7 6.0 22.6 1.3 1 0 0 1 1 1 0 SDA1 XPG_I_2 PF12813.7 OAJ19546.1 - 1.7e-07 30.9 0.0 0.00011 21.8 0.0 3.2 2 1 0 2 2 2 2 XPG domain containing XPG_N PF00752.17 OAJ19546.1 - 4.2e-05 24.0 0.0 8.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ19546.1 - 0.017 15.5 1.1 0.049 14.0 0.0 2.2 2 0 0 2 2 2 0 XPG I-region YL1 PF05764.13 OAJ19546.1 - 0.23 11.6 14.4 0.11 12.5 5.3 2.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF4611 PF15387.6 OAJ19546.1 - 3.8 7.8 12.8 5.7 7.2 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 OAJ19546.1 - 4.3 5.3 14.7 7.5 4.5 14.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi DPBB_1 PF03330.18 OAJ19547.1 - 9.7e-05 22.6 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ19547.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Barwin family DUF3775 PF12616.8 OAJ19549.1 - 0.054 13.5 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) FAD_binding_4 PF01565.23 OAJ19550.1 - 3.3e-25 88.4 4.0 3.3e-25 88.4 4.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ19550.1 - 4.5e-09 36.3 0.2 8.7e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like GCP_C_terminal PF04130.13 OAJ19551.1 - 2.7e-42 145.3 0.0 4.8e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ19551.1 - 3.5e-10 40.0 0.0 1.1e-08 35.1 0.0 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal AIP3 PF03915.13 OAJ19552.1 - 1.9e-125 419.2 0.3 2.7e-125 418.7 0.3 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1640 PF07798.11 OAJ19552.1 - 0.013 15.6 0.2 0.047 13.7 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) IFT57 PF10498.9 OAJ19552.1 - 0.043 12.8 0.4 0.085 11.8 0.0 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Lectin_N PF03954.14 OAJ19552.1 - 0.092 12.5 0.8 0.84 9.4 0.0 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CHDCT2 PF08074.11 OAJ19552.1 - 0.17 12.0 0.9 0.97 9.6 0.1 2.5 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Halo_GVPC PF05465.13 OAJ19552.1 - 0.49 10.7 2.8 0.85 9.9 0.3 2.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Tma16 PF11176.8 OAJ19553.1 - 3.5e-38 130.8 0.1 4.3e-38 130.5 0.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 FdsD PF11390.8 OAJ19553.1 - 0.09 13.1 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD DUF5436 PF17504.2 OAJ19553.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) EB PF01683.18 OAJ19554.1 - 0.016 15.5 7.2 0.016 15.5 7.2 10.4 4 3 3 8 8 8 0 EB module 4HBT_3 PF13622.6 OAJ19555.1 - 2.7e-34 119.5 0.7 8.9e-34 117.8 0.7 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ19555.1 - 0.00065 19.5 0.1 0.0015 18.4 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase 4HBT PF03061.22 OAJ19555.1 - 0.065 13.6 0.1 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily DUF5136 PF17199.4 OAJ19557.1 - 0.11 12.2 0.8 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5136) SAS4 PF15460.6 OAJ19558.1 - 0.018 15.1 0.1 0.048 13.7 0.1 1.7 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 NUC153 PF08159.12 OAJ19561.1 - 9.1e-11 41.4 7.7 1.4e-09 37.6 0.0 3.7 3 0 0 3 3 3 1 NUC153 domain TMEM51 PF15345.6 OAJ19561.1 - 0.0015 18.4 2.3 0.0015 18.4 2.3 3.1 4 0 0 4 4 4 1 Transmembrane protein 51 DUF2457 PF10446.9 OAJ19561.1 - 0.0018 17.5 24.2 0.0018 17.5 24.2 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF2457) BUD22 PF09073.10 OAJ19561.1 - 0.0037 16.7 28.1 0.0037 16.7 28.1 4.4 3 2 0 4 4 4 1 BUD22 Brix PF04427.18 OAJ19581.1 - 1.1e-38 133.4 0.0 1.3e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Acyltransferase PF01553.21 OAJ19582.1 - 1.6e-22 79.6 0.0 2.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAJ19582.1 - 7.7e-07 29.1 1.5 1.1e-06 28.6 0.1 1.9 2 0 0 2 2 2 1 Acyltransferase C-terminus NAR2 PF16974.5 OAJ19583.1 - 0.0029 17.0 0.2 0.0051 16.2 0.2 1.4 1 0 0 1 1 1 1 High-affinity nitrate transporter accessory TcfC PF16967.5 OAJ19583.1 - 0.038 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 E-set like domain Alph_Pro_TM PF09608.10 OAJ19583.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NOA36 PF06524.12 OAJ19583.1 - 0.68 9.2 5.2 0.58 9.4 2.5 1.9 2 0 0 2 2 2 0 NOA36 protein DUF3439 PF11921.8 OAJ19583.1 - 0.71 9.8 11.1 0.14 12.1 6.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CAP PF00188.26 OAJ19584.1 - 1e-06 29.6 0.0 1.5e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SE PF08491.10 OAJ19585.1 - 3.3e-80 269.1 0.0 5.6e-36 124.0 0.0 3.3 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.24 OAJ19585.1 - 1.7e-10 41.0 0.4 1.2e-07 31.7 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ19585.1 - 5.7e-10 39.0 0.2 6e-06 25.7 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ19585.1 - 2.7e-05 24.3 0.9 8.9e-05 22.7 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAJ19585.1 - 0.00024 20.3 0.4 0.0011 18.1 0.3 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 OAJ19585.1 - 0.0005 19.3 1.0 0.0019 17.4 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 OAJ19585.1 - 0.00097 18.6 0.1 0.0014 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 OAJ19585.1 - 0.0016 18.1 0.1 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 OAJ19585.1 - 0.0021 17.3 0.0 0.0049 16.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ19585.1 - 0.0029 17.5 0.1 0.0048 16.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ19585.1 - 0.0032 16.8 0.0 0.013 14.7 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 OAJ19585.1 - 0.0059 17.1 0.0 0.031 14.8 0.1 2.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 OAJ19585.1 - 0.007 16.2 0.5 0.023 14.6 0.1 2.0 2 0 0 2 2 1 1 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAJ19585.1 - 0.024 14.9 0.1 0.041 14.2 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 OAJ19585.1 - 0.032 13.1 1.0 0.22 10.3 0.2 2.1 1 1 1 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 OAJ19585.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 OAJ19585.1 - 0.12 11.0 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 OAJ19585.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Lycopene_cycl PF05834.12 OAJ19585.1 - 0.31 10.0 1.3 0.41 9.7 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Peptidase_M16_C PF05193.21 OAJ19586.1 - 7.6e-22 78.2 0.0 2.4e-16 60.3 0.0 3.3 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAJ19586.1 - 1.2e-07 31.8 0.0 5.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Oxysterol_BP PF01237.18 OAJ19586.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein MBOAT_2 PF13813.6 OAJ19587.1 - 3.5e-09 36.8 3.2 6.5e-07 29.5 3.2 2.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family DUF969 PF06149.12 OAJ19588.1 - 0.18 11.2 1.4 0.29 10.5 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF969) DUF3591 PF12157.8 OAJ19589.1 - 8e-172 571.8 0.2 1e-171 571.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 OAJ19589.1 - 1.6e-05 24.6 4.2 5.1e-05 23.0 4.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ19589.1 - 0.034 14.2 1.6 0.06 13.5 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle TPR_2 PF07719.17 OAJ19590.1 - 1.6e-31 105.8 13.3 9.1e-05 22.3 0.1 9.9 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19590.1 - 5.9e-22 77.7 7.3 1.1e-08 35.2 0.7 5.7 4 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAJ19590.1 - 1.4e-21 75.3 7.4 0.0061 16.3 0.0 8.9 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19590.1 - 2.8e-15 56.4 16.4 3.9e-07 30.3 0.2 7.6 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19590.1 - 4.1e-15 56.1 18.8 0.00015 22.3 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19590.1 - 3.8e-14 51.6 0.7 0.39 11.0 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ19590.1 - 1.3e-10 40.9 0.2 1.4 9.5 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19590.1 - 2.1e-10 41.0 19.0 0.17 12.4 0.5 7.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19590.1 - 1.4e-09 37.9 28.3 0.29 12.1 0.6 9.4 5 1 5 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19590.1 - 4.7e-09 35.8 6.1 0.2 11.4 0.0 8.4 8 2 2 10 10 10 2 TPR repeat TPR_7 PF13176.6 OAJ19590.1 - 1.5e-06 27.8 11.9 0.16 12.0 0.0 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19590.1 - 6.7e-06 25.8 11.2 0.22 11.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19590.1 - 7.3e-05 23.1 17.1 3.4 8.5 0.0 7.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ19590.1 - 9.8e-05 22.4 12.5 0.22 11.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ19590.1 - 0.012 15.0 0.5 0.012 15.0 0.5 4.0 3 1 2 5 5 5 0 MalT-like TPR region BTAD PF03704.17 OAJ19590.1 - 0.017 15.5 3.1 0.6 10.5 0.3 3.4 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 OAJ19590.1 - 2.7 8.4 10.9 36 4.8 0.2 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 OAJ19591.1 - 9.9e-28 96.3 0.2 1.3e-27 95.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Gcd10p PF04189.13 OAJ19592.1 - 2.2e-63 214.1 0.0 4.8e-63 213.1 0.0 1.5 2 0 0 2 2 2 1 Gcd10p family Tir_receptor_C PF07489.11 OAJ19592.1 - 0.0035 17.4 0.2 0.0088 16.0 0.1 1.6 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus FGGY_N PF00370.21 OAJ19593.1 - 5.5e-74 248.8 0.2 8.3e-74 248.2 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OAJ19593.1 - 1.6e-67 227.1 3.4 3.9e-67 225.8 1.9 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Cupin_8 PF13621.6 OAJ19594.1 - 4.5e-39 134.7 5.2 5.4e-20 72.2 0.0 4.7 4 1 0 4 4 4 2 Cupin-like domain Acyl-thio_N PF12590.8 OAJ19594.1 - 0.033 14.8 2.0 0.13 12.8 0.0 3.1 3 1 0 3 3 3 0 Acyl-ATP thioesterase Aminotran_3 PF00202.21 OAJ19596.1 - 2.3e-34 118.7 0.0 1.2e-16 60.4 0.0 3.3 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 OAJ19596.1 - 1.6e-09 37.9 0.0 6.2e-09 36.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.16 OAJ19597.1 - 1.5e-10 40.5 17.1 2.8e-10 39.7 17.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 OAJ19598.1 - 2.5e-33 114.8 0.7 4.8e-33 113.9 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ19598.1 - 4.2e-16 60.2 0.0 7e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ19598.1 - 2.1e-05 24.4 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAJ19598.1 - 0.0027 17.1 0.5 0.0045 16.3 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAJ19598.1 - 0.042 13.3 0.3 0.084 12.3 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase HupF_HypC PF01455.18 OAJ19598.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 HupF/HypC family Ribosomal_L4 PF00573.22 OAJ19602.1 - 4e-61 206.1 0.0 5.8e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.6 OAJ19602.1 - 0.18 11.9 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Kinesin PF00225.23 OAJ19604.1 - 8.2e-105 350.4 0.0 2.1e-104 349.1 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ19604.1 - 9.1e-27 93.8 0.0 2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 OAJ19604.1 - 9.6 5.4 64.8 0.052 12.9 3.6 4.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4407) LapA_dom PF06305.11 OAJ19605.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Dicty_REP PF05086.12 OAJ19605.1 - 1.5 6.7 6.4 2.1 6.2 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRO1 PF03097.18 OAJ19606.1 - 5.8e-105 351.3 0.1 1.5e-104 350.0 0.1 1.7 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ19606.1 - 1.2e-65 221.8 12.3 2.5e-65 220.7 12.3 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CAP_N PF01213.19 OAJ19606.1 - 0.0071 15.9 1.9 0.019 14.5 1.9 1.7 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF1043 PF06295.12 OAJ19606.1 - 3 7.9 6.7 18 5.4 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) HAUS6_N PF14661.6 OAJ19606.1 - 8 6.0 8.4 3.6 7.1 5.5 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SUI1 PF01253.22 OAJ19607.1 - 1.8e-13 50.8 0.0 4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pol_alpha_B_N PF08418.10 OAJ19607.1 - 0.045 13.7 1.7 0.07 13.1 1.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal GA PF01468.17 OAJ19607.1 - 0.11 12.7 6.5 0.12 12.7 2.6 2.7 3 0 0 3 3 3 0 GA module Clr2_transil PF16761.5 OAJ19608.1 - 2e-09 38.1 0.7 4.3e-09 37.1 0.7 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAJ19608.1 - 8e-07 29.9 0.0 1.5e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 PI-PLC-C1 PF16670.5 OAJ19609.1 - 0.016 14.3 0.3 1.7 7.7 0.0 2.6 2 1 1 3 3 3 0 Phosphoinositide phospholipase C, Ca2+-dependent MFS_1 PF07690.16 OAJ19610.1 - 6.6e-35 120.7 27.6 6.6e-35 120.7 27.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.27 OAJ19611.1 - 2.1e-46 157.8 0.0 1.3e-24 87.2 0.0 3.4 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 OAJ19611.1 - 9.9e-16 58.4 0.3 0.0042 16.9 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ19611.1 - 4.3e-10 39.4 0.1 0.034 13.6 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ19611.1 - 4.6e-08 33.8 2.8 0.00071 20.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain Chromo PF00385.24 OAJ19611.1 - 9.2e-07 28.7 0.1 1.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 OAJ19611.1 - 2.5e-06 27.1 0.1 0.1 12.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ19611.1 - 1.6e-05 24.9 0.0 0.011 15.9 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ19611.1 - 1.9e-05 25.1 4.9 0.022 15.1 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 OAJ19611.1 - 2.9e-05 24.4 0.1 1 9.6 0.0 3.8 3 0 0 3 3 3 2 AAA domain HEAT_EZ PF13513.6 OAJ19611.1 - 3.5e-05 24.2 4.4 22 5.7 0.0 6.1 5 1 1 6 6 5 0 HEAT-like repeat HEAT_2 PF13646.6 OAJ19611.1 - 0.00047 20.5 8.0 4.6 7.7 0.4 5.3 3 2 0 4 4 4 1 HEAT repeats AAA_28 PF13521.6 OAJ19611.1 - 0.0016 18.7 0.2 1.1 9.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ19611.1 - 0.0018 18.2 0.2 0.08 12.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 OAJ19611.1 - 0.0024 16.9 0.4 0.34 9.9 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 OAJ19611.1 - 0.0035 17.1 0.1 0.81 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OAJ19611.1 - 0.0042 17.0 0.1 8.2 6.3 0.0 3.4 3 0 0 3 3 3 0 NACHT domain Cnd1 PF12717.7 OAJ19611.1 - 0.008 16.2 0.6 0.68 10.0 0.1 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_24 PF13479.6 OAJ19611.1 - 0.0083 15.9 0.1 4.5 7.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OAJ19611.1 - 0.009 15.8 0.4 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAJ19611.1 - 0.011 15.9 0.0 0.34 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.8 OAJ19611.1 - 0.013 15.0 0.2 0.82 9.2 0.1 2.6 1 1 1 2 2 2 0 CLASP N terminal DUF87 PF01935.17 OAJ19611.1 - 0.02 15.0 0.1 10 6.1 0.0 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_27 PF13514.6 OAJ19611.1 - 0.031 13.9 0.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dopey_N PF04118.14 OAJ19611.1 - 0.04 13.0 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Dopey, N-terminal Zeta_toxin PF06414.12 OAJ19611.1 - 0.042 13.1 0.2 8.8 5.5 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin ALF PF03752.13 OAJ19611.1 - 0.06 13.3 1.5 0.67 10.0 0.1 2.9 2 0 0 2 2 2 0 Short repeats of unknown function AAA_18 PF13238.6 OAJ19611.1 - 0.079 13.5 0.0 11 6.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ19611.1 - 0.088 12.4 0.1 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OAJ19611.1 - 0.098 13.1 0.0 5.5 7.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase HEAT PF02985.22 OAJ19611.1 - 0.26 11.6 7.4 34 5.1 0.0 5.6 6 0 0 6 6 5 0 HEAT repeat NAD_binding_8 PF13450.6 OAJ19634.1 - 0.0011 19.1 0.1 0.0076 16.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ19634.1 - 0.013 14.8 0.2 0.035 13.3 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ19634.1 - 0.1 12.2 0.2 0.41 10.2 0.1 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ19634.1 - 0.14 12.1 0.1 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ19635.1 - 1.9e-16 60.2 0.0 8.6e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ19635.1 - 6.1e-14 52.0 0.6 3.6e-13 49.4 0.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAJ19635.1 - 3.1e-13 49.0 0.1 6.4e-11 41.4 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAJ19635.1 - 2.4e-08 34.1 0.0 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 OAJ19635.1 - 4.1e-08 32.8 0.4 0.00012 21.4 0.0 3.5 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAJ19635.1 - 3.7e-07 30.1 3.5 9.5e-05 22.1 0.2 3.7 3 2 1 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ19635.1 - 1.1e-06 28.0 0.1 0.009 15.1 0.0 3.7 4 0 0 4 4 4 2 Lycopene cyclase protein Thi4 PF01946.17 OAJ19635.1 - 2.1e-06 27.2 0.2 2.4e-05 23.7 0.0 2.3 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 OAJ19635.1 - 3.6e-05 23.8 0.5 0.4 10.7 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAJ19635.1 - 7.5e-05 22.0 0.1 0.00061 19.0 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ19635.1 - 0.00023 21.7 0.0 0.78 10.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAJ19635.1 - 0.00031 19.4 0.1 0.39 9.2 0.1 2.3 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.22 OAJ19635.1 - 0.0074 15.4 1.1 0.38 9.8 0.2 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAJ19635.1 - 0.0086 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 OAJ19635.1 - 0.031 14.4 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 OAJ19635.1 - 0.033 12.9 0.2 0.34 9.6 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.14 OAJ19635.1 - 0.061 12.2 0.6 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 OAJ19635.1 - 0.17 11.1 0.0 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ADH_zinc_N PF00107.26 OAJ19636.1 - 4.5e-09 36.4 0.0 9.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ19636.1 - 0.0082 16.0 0.0 0.068 13.1 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MBOAT_2 PF13813.6 OAJ19637.1 - 2.4e-13 50.1 0.1 1.9e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Rad52_Rad22 PF04098.15 OAJ19637.1 - 2.2e-08 34.2 0.1 3.9e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TENA_THI-4 PF03070.16 OAJ19638.1 - 3.4e-12 46.6 0.0 5.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family SRP-alpha_N PF04086.13 OAJ19639.1 - 1.8 8.4 8.6 2.2 8.1 8.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal WLM PF08325.10 OAJ19639.1 - 4.1 7.4 6.5 1.6 8.7 4.0 1.5 1 1 1 2 2 2 0 WLM domain PIN_4 PF13638.6 OAJ19640.1 - 1.4e-21 77.1 0.0 4.5e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 PIN domain Apolipoprotein PF01442.18 OAJ19641.1 - 0.029 14.3 7.0 0.07 13.0 7.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DBINO PF13892.6 OAJ19641.1 - 0.25 11.7 9.1 0.53 10.6 9.1 1.5 1 0 0 1 1 1 0 DNA-binding domain Arf PF00025.21 OAJ19642.1 - 1.4e-79 265.6 0.1 1.6e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ19642.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ19642.1 - 4.5e-14 52.3 0.0 5.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAJ19642.1 - 2e-13 50.2 0.8 1.7e-09 37.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAJ19642.1 - 3.7e-13 49.4 0.0 4.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAJ19642.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ19642.1 - 3.3e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ19642.1 - 0.0067 15.8 0.5 0.017 14.4 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Nbl1_Borealin_N PF10444.9 OAJ19644.1 - 3.9e-12 45.6 0.4 6.4e-12 44.9 0.4 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Peptidase_S49_N PF08496.10 OAJ19644.1 - 2.5 8.1 7.6 0.79 9.8 4.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.25 OAJ19645.1 - 0.018 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Yip1 PF04893.17 OAJ19646.1 - 0.37 10.5 4.8 0.14 11.8 0.5 2.1 2 0 0 2 2 2 0 Yip1 domain GTP_CH_N PF12471.8 OAJ19647.1 - 1.9e-87 292.0 0.0 2.9e-87 291.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAJ19647.1 - 7.2e-16 58.2 0.0 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II ABC2_membrane PF01061.24 OAJ19648.1 - 6.7e-80 267.4 54.9 3.4e-41 141.0 24.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ19648.1 - 1.8e-39 135.4 0.0 3.7e-19 69.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ19648.1 - 5.3e-20 71.1 8.7 1.6e-17 63.1 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 OAJ19648.1 - 3.3e-11 43.7 0.4 7.5e-11 42.5 0.4 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal SMC_N PF02463.19 OAJ19648.1 - 1.1e-06 28.3 0.0 9.8e-05 21.9 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ19648.1 - 2.8e-05 24.1 0.0 0.14 11.9 0.0 2.8 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ19648.1 - 4e-05 23.3 0.6 0.021 14.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 OAJ19648.1 - 0.00014 22.1 0.8 0.11 12.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ19648.1 - 0.00035 20.5 0.1 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAJ19648.1 - 0.00036 21.0 0.1 0.073 13.5 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 OAJ19648.1 - 0.0019 17.8 0.2 0.013 15.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ19648.1 - 0.0026 18.0 0.1 0.76 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ19648.1 - 0.0035 17.9 5.6 0.035 14.7 0.0 3.4 3 1 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.23 OAJ19648.1 - 0.0064 16.6 0.2 5.3 7.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAJ19648.1 - 0.0086 15.8 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAJ19648.1 - 0.012 15.2 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OAJ19648.1 - 0.013 15.2 0.1 4.7 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ19648.1 - 0.025 15.0 0.0 18 5.8 0.0 3.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ19648.1 - 0.053 13.4 0.6 4.1 7.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Cas_Csy1 PF09611.10 OAJ19648.1 - 0.062 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) AAA_28 PF13521.6 OAJ19648.1 - 0.073 13.3 0.0 0.25 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 OAJ19648.1 - 0.08 12.2 0.2 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 OAJ19648.1 - 0.084 13.3 0.1 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 OAJ19648.1 - 1.8 7.6 57.5 0.01 15.0 19.9 2.9 3 1 0 3 3 2 0 ABC-2 family transporter protein DUF1440 PF07274.12 OAJ19648.1 - 3.9 7.8 5.6 20 5.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) DPBB_1 PF03330.18 OAJ19649.1 - 6.3e-06 26.4 0.2 1.9e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 Lytic transglycolase Mucin PF01456.17 OAJ19649.1 - 0.0019 18.2 13.1 0.0019 18.2 13.1 2.1 2 0 0 2 2 2 1 Mucin-like glycoprotein Sporozoite_P67 PF05642.11 OAJ19649.1 - 0.013 13.6 11.0 0.054 11.6 10.9 1.8 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Barwin PF00967.17 OAJ19649.1 - 0.015 15.1 0.4 0.035 14.0 0.4 1.6 1 0 0 1 1 1 0 Barwin family SOG2 PF10428.9 OAJ19649.1 - 0.14 11.3 12.4 0.016 14.4 8.2 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein TonB_N PF16031.5 OAJ19649.1 - 0.17 12.4 23.7 0.35 11.4 23.7 1.4 1 0 0 1 1 1 0 TonB polyproline region CPSF100_C PF13299.6 OAJ19649.1 - 0.33 11.1 4.7 0.56 10.4 4.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 OAJ19649.1 - 0.68 9.7 8.3 0.95 9.2 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 OAJ19649.1 - 0.77 9.6 10.7 1.2 8.9 10.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SLC12 PF03522.15 OAJ19649.1 - 1 8.3 6.7 1.2 8.1 6.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Apt1 PF10351.9 OAJ19649.1 - 1.7 7.4 12.6 2.3 7.0 12.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glypican PF01153.19 OAJ19649.1 - 3.6 6.3 6.8 5.2 5.8 6.8 1.2 1 0 0 1 1 1 0 Glypican CDC45 PF02724.14 OAJ19649.1 - 4.8 5.3 8.4 6.4 4.9 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 OAJ19649.1 - 8.1 4.9 11.8 12 4.4 11.8 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 OAJ19649.1 - 9.4 4.4 9.7 15 3.7 9.7 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S10 PF00450.22 OAJ19650.1 - 1.5e-98 331.0 0.0 1.8e-98 330.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 OAJ19651.1 - 3.6e-28 98.6 5.2 6e-22 78.1 0.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ19651.1 - 2.2e-24 86.0 59.3 1.1e-16 60.7 10.4 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF485 PF04341.12 OAJ19651.1 - 0.019 14.9 0.5 7.9 6.5 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 YL1 PF05764.13 OAJ19653.1 - 0.0016 18.6 31.7 0.0024 18.1 31.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 OAJ19653.1 - 0.0083 15.6 31.2 0.011 15.2 31.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 OAJ19653.1 - 0.016 13.5 34.6 0.02 13.1 34.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.7 OAJ19653.1 - 0.066 11.3 6.5 0.075 11.2 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.12 OAJ19653.1 - 0.18 10.3 34.1 0.39 9.3 34.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 OAJ19653.1 - 0.28 9.3 38.3 0.37 8.9 38.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi SLC12 PF03522.15 OAJ19653.1 - 0.31 10.0 11.5 0.4 9.7 11.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 OAJ19653.1 - 0.72 8.6 15.6 0.95 8.2 15.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 OAJ19653.1 - 1.4 7.2 31.4 1.9 6.7 31.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 OAJ19653.1 - 2.2 7.6 33.0 3.3 7.0 33.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GREB1 PF15782.5 OAJ19653.1 - 7.2 3.6 8.5 7.9 3.5 8.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Aa_trans PF01490.18 OAJ19654.1 - 0.13 10.9 0.7 0.22 10.2 0.7 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein PPP4R2 PF09184.11 OAJ19654.1 - 0.17 11.4 0.1 0.28 10.7 0.1 1.2 1 0 0 1 1 1 0 PPP4R2 CENP-B_dimeris PF09026.10 OAJ19654.1 - 1.2 9.5 11.4 0.18 12.2 6.6 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3262 PF11660.8 OAJ19654.1 - 1.8 9.0 5.8 1.7 9.0 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) NOA36 PF06524.12 OAJ19654.1 - 3.5 6.8 5.8 6.3 6.0 5.8 1.3 1 0 0 1 1 1 0 NOA36 protein Hydrolase_like PF13242.6 OAJ19655.1 - 3.4e-22 78.3 0.1 6.1e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAJ19655.1 - 1.5e-16 60.3 0.0 3.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SRF-TF PF00319.18 OAJ19656.1 - 5e-17 61.1 0.1 8e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.8 OAJ19656.1 - 2.4 7.5 10.1 1.1 8.7 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3246) Zn_Tnp_IS1595 PF12760.7 OAJ19658.1 - 0.0045 16.9 0.5 0.014 15.3 0.4 1.8 1 1 1 2 2 2 1 Transposase zinc-ribbon domain Pyr_redox_2 PF07992.14 OAJ19659.1 - 2e-23 83.1 0.2 5e-13 48.9 0.0 4.2 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ19659.1 - 1.1e-11 45.1 1.2 3e-08 34.1 1.4 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 OAJ19659.1 - 0.0087 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ19659.1 - 0.036 13.5 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 OAJ19659.1 - 0.13 11.0 0.1 0.74 8.5 0.0 1.9 2 0 0 2 2 2 0 Serine carboxypeptidase S28 DUF2920 PF11144.8 OAJ19659.1 - 0.29 10.3 0.0 0.44 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF202 PF02656.15 OAJ19660.1 - 0.19 12.2 10.5 12 6.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF3712 PF12505.8 OAJ19661.1 - 1.8e-23 83.1 0.0 6.2e-11 42.6 0.0 4.6 3 1 0 3 3 3 3 Protein of unknown function (DUF3712) Ribosomal_S15 PF00312.22 OAJ19662.1 - 3.2e-23 81.7 0.3 3.2e-23 81.7 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_L3 PF00297.22 OAJ19663.1 - 3.5e-19 69.0 1.2 3e-18 65.9 1.0 2.3 1 1 2 3 3 3 1 Ribosomal protein L3 DUF3149 PF11346.8 OAJ19664.1 - 5.6 6.7 6.0 3.3 7.4 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3149) ABC_tran PF00005.27 OAJ19681.1 - 2.2e-43 148.1 0.1 7.3e-24 84.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 OAJ19681.1 - 2.1e-39 135.8 17.5 9.1e-22 78.0 5.7 4.0 5 0 0 5 5 5 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ19681.1 - 2.6e-09 36.9 0.0 0.00024 20.6 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ19681.1 - 7.3e-06 26.3 0.2 0.023 15.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ19681.1 - 0.00016 21.3 0.3 0.4 10.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 OAJ19681.1 - 0.00063 18.9 0.2 0.29 10.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ19681.1 - 0.0012 18.5 0.6 0.14 11.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase PF06745.13 OAJ19681.1 - 0.0086 15.4 0.2 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 KaiC DEAD PF00270.29 OAJ19681.1 - 0.052 13.3 0.4 16 5.2 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 OAJ19681.1 - 0.066 12.1 0.1 7.7 5.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 OAJ19681.1 - 0.067 12.9 0.0 0.5 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ19681.1 - 0.083 12.5 0.9 0.45 10.1 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 OAJ19681.1 - 0.089 12.2 0.2 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein SieB PF14163.6 OAJ19681.1 - 0.12 11.9 1.3 0.36 10.3 1.3 1.8 1 0 0 1 1 1 0 Super-infection exclusion protein B AAA_7 PF12775.7 OAJ19681.1 - 0.15 11.6 0.0 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAJ19681.1 - 0.18 11.5 1.8 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 OAJ19681.1 - 1.3 9.5 10.5 1.9 9.0 0.1 3.2 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAJ19681.1 - 2.4 8.2 5.4 0.25 11.4 0.1 2.0 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_16 PF13191.6 OAJ19681.1 - 3.1 8.1 15.7 0.33 11.3 2.7 4.1 4 1 0 4 4 3 0 AAA ATPase domain CDC45 PF02724.14 OAJ19681.1 - 3.5 5.8 6.5 6 5.0 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GYF PF02213.16 OAJ19682.1 - 0.002 17.7 0.0 0.0061 16.2 0.0 1.7 1 0 0 1 1 1 1 GYF domain Mur_ligase_M PF08245.12 OAJ19683.1 - 0.00021 21.3 2.1 0.0075 16.3 2.1 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 OAJ19683.1 - 0.03 14.6 0.0 0.18 12.1 0.0 2.3 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain UCH_C PF18031.1 OAJ19683.1 - 0.25 11.3 0.3 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases FtsJ PF01728.19 OAJ19684.1 - 8.9e-53 179.0 0.0 3.4e-42 144.5 0.0 2.0 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OAJ19684.1 - 0.00065 20.4 0.0 0.0018 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OAJ19684.1 - 0.0081 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_24 PF13578.6 OAJ19684.1 - 0.026 15.5 0.0 0.16 13.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ19684.1 - 0.029 14.2 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ19684.1 - 0.043 13.2 0.0 0.22 10.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family WD40 PF00400.32 OAJ19685.1 - 2.2e-37 126.4 15.1 3.3e-07 30.9 0.4 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19685.1 - 6.5e-10 39.2 1.1 0.3 11.4 0.0 6.5 2 1 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ19685.1 - 2e-05 23.5 1.2 0.23 10.1 0.1 3.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 OAJ19685.1 - 0.0019 17.2 0.7 0.36 9.7 0.0 3.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 OAJ19685.1 - 0.0043 16.7 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain PQQ_3 PF13570.6 OAJ19685.1 - 1.2 9.7 5.0 28 5.4 0.0 4.3 5 1 0 5 5 5 0 PQQ-like domain Ribosomal_L3 PF00297.22 OAJ19686.1 - 1.1e-182 607.1 7.8 1.2e-182 606.9 7.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DnaJ PF00226.31 OAJ19687.1 - 1.2e-18 67.0 0.1 2.3e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1682 PF07946.14 OAJ19687.1 - 0.056 12.6 6.3 0.072 12.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Macoilin PF09726.9 OAJ19687.1 - 1.3 7.5 5.3 1.8 7.0 5.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF202 PF02656.15 OAJ19688.1 - 7.5e-14 51.9 5.3 7.5e-14 51.9 5.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX2_TM PF02790.15 OAJ19688.1 - 0.0038 17.4 0.7 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane domain DUF5337 PF17272.2 OAJ19688.1 - 1.3 8.9 6.6 1.9 8.4 5.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF2615 PF11027.8 OAJ19688.1 - 3.1 8.0 4.1 1.6 8.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) RhoGEF PF00621.20 OAJ19689.1 - 4.7e-31 108.4 0.0 7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 OAJ19689.1 - 7e-18 64.5 9.6 1.4e-17 63.6 9.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OAJ19689.1 - 7.1e-05 23.3 0.0 0.0011 19.4 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 OAJ19689.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain zf-RING_2 PF13639.6 OAJ19689.1 - 0.16 12.4 5.5 0.36 11.2 5.5 1.6 1 0 0 1 1 1 0 Ring finger domain Glt_symporter PF03616.14 OAJ19689.1 - 0.3 9.7 1.1 0.47 9.1 1.1 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter FYVE_2 PF02318.16 OAJ19689.1 - 0.9 9.8 6.1 1.9 8.7 6.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger TPR_2 PF07719.17 OAJ19690.1 - 6e-29 97.8 55.6 6.5e-05 22.8 0.7 17.3 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19690.1 - 1.5e-28 97.4 26.1 4.1e-05 23.2 0.3 13.5 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19690.1 - 2.4e-23 80.3 16.6 0.022 14.9 0.2 14.0 14 1 0 14 14 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19690.1 - 4.7e-20 71.0 10.2 0.00016 21.3 0.0 9.0 9 1 1 10 10 9 6 TPR repeat TPR_14 PF13428.6 OAJ19690.1 - 2.3e-18 65.3 68.7 0.00041 20.9 0.1 17.7 15 2 3 18 18 17 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ19690.1 - 3.3e-14 52.2 20.0 0.057 13.8 0.0 12.8 13 1 0 13 13 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19690.1 - 8.2e-12 45.6 97.0 3.3e-05 24.4 1.6 16.4 14 3 1 16 16 16 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19690.1 - 5.6e-10 38.5 28.8 0.17 12.0 0.0 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19690.1 - 7.7e-10 38.9 65.5 1.1e-07 32.0 0.9 12.8 13 2 1 14 14 14 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19690.1 - 3.8e-09 36.6 38.1 0.041 14.5 0.1 13.2 16 0 0 16 16 13 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19690.1 - 4e-06 26.5 14.9 0.0082 16.0 0.1 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ19690.1 - 0.00012 22.1 40.0 1.5 9.0 0.4 11.7 12 1 1 13 13 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19690.1 - 0.00016 22.1 49.9 0.019 15.5 0.4 11.4 9 3 4 13 13 12 5 Tetratricopeptide repeat BTAD PF03704.17 OAJ19690.1 - 0.0028 18.1 1.2 0.0028 18.1 1.2 7.0 7 1 0 7 7 6 2 Bacterial transcriptional activator domain TPR_22 PF18833.1 OAJ19690.1 - 0.016 15.3 0.1 0.067 13.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat FAT PF02259.23 OAJ19690.1 - 0.15 11.3 7.6 2.3 7.4 2.1 4.0 4 1 1 5 5 5 0 FAT domain BIV_Env PF05858.12 OAJ19690.1 - 0.15 10.3 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) ChAPs PF09295.10 OAJ19690.1 - 1.3 8.0 4.9 6.1 5.7 0.0 3.2 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 OAJ19690.1 - 2.9 8.2 26.3 0.34 11.2 0.7 7.0 6 2 1 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 OAJ19690.1 - 8.1 6.5 11.7 1.7 8.7 0.3 4.9 5 0 0 5 5 5 0 Domain of Unknown Function (DUF3856) Zn_clus PF00172.18 OAJ19691.1 - 1.9e-05 24.7 8.0 0.0002 21.4 8.0 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ19691.1 - 0.69 9.8 20.1 2.2 8.2 1.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4632 PF15451.6 OAJ19691.1 - 0.81 9.8 5.6 2 8.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) SUIM_assoc PF16619.5 OAJ19691.1 - 4.5 7.4 9.9 38 4.5 5.4 3.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Chitin_synth_2 PF03142.15 OAJ19692.1 - 4.2e-237 787.9 0.0 5.9e-237 787.4 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ19692.1 - 3e-11 43.6 9.3 3e-11 43.6 9.3 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAJ19692.1 - 3e-11 43.7 0.5 1.7e-10 41.2 0.3 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ19692.1 - 0.0034 16.9 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF3149 PF11346.8 OAJ19692.1 - 0.041 13.5 3.4 0.13 11.9 3.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) AAR2 PF05282.11 OAJ19693.1 - 5.2e-49 167.5 0.2 6.3e-49 167.3 0.2 1.0 1 0 0 1 1 1 1 AAR2 protein zf-RING_2 PF13639.6 OAJ19694.1 - 3.3e-07 30.5 8.1 6e-07 29.7 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAJ19694.1 - 0.00072 19.8 5.6 0.0016 18.7 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ19694.1 - 0.0015 18.6 1.5 0.0031 17.5 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAJ19694.1 - 0.0055 16.9 3.7 0.013 15.6 3.7 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OAJ19694.1 - 0.014 15.3 8.4 0.024 14.5 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAJ19694.1 - 0.021 14.9 6.1 0.05 13.7 6.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 OAJ19694.1 - 0.035 14.0 7.6 0.075 12.9 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 OAJ19694.1 - 0.052 13.5 2.9 0.26 11.3 3.5 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TIMELESS_C PF05029.13 OAJ19694.1 - 0.27 10.3 2.7 0.48 9.5 2.7 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region Virul_fac_BrkB PF03631.15 OAJ19694.1 - 0.33 10.5 2.3 2.6 7.6 0.2 3.1 2 0 0 2 2 2 0 Virulence factor BrkB C1_1 PF00130.22 OAJ19694.1 - 0.42 10.5 3.4 0.86 9.5 3.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 OAJ19694.1 - 0.88 9.9 5.1 1.8 9.0 5.1 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAJ19694.1 - 1 9.0 3.7 2 8.1 3.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CobT PF06213.12 OAJ19694.1 - 2.3 7.6 5.6 3.9 6.8 3.1 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT PHD PF00628.29 OAJ19694.1 - 2.4 8.1 5.2 4.3 7.3 5.2 1.4 1 0 0 1 1 1 0 PHD-finger HEAT_PBS PF03130.16 OAJ19694.1 - 2.4 9.1 5.0 53 4.9 0.3 4.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat K-cyclin_vir_C PF09080.10 OAJ19694.1 - 8.7 6.8 7.4 13 6.3 0.0 3.8 4 0 0 4 4 4 0 K cyclin, C terminal BTB PF00651.31 OAJ19696.1 - 2.6e-06 27.6 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Pex14_N PF04695.13 OAJ19696.1 - 0.0037 17.9 7.1 0.0037 17.9 7.1 3.4 2 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.9 OAJ19696.1 - 0.016 15.3 16.5 0.016 15.3 16.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) BRF1 PF07741.13 OAJ19696.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.8 2 1 0 2 2 1 0 Brf1-like TBP-binding domain TFIIA PF03153.13 OAJ19696.1 - 0.14 12.1 24.5 0.13 12.2 17.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 OAJ19696.1 - 0.56 10.2 4.6 2 8.3 0.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Hydin_ADK PF17213.3 OAJ19696.1 - 0.94 9.7 9.9 0.69 10.2 0.9 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain eIF-3_zeta PF05091.12 OAJ19696.1 - 0.96 8.4 5.8 2.1 7.2 5.8 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.15 OAJ19696.1 - 1.1 8.0 4.5 14 4.4 1.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 OAJ19696.1 - 1.2 9.2 4.3 2.2 8.3 0.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 OAJ19696.1 - 1.8 7.3 13.0 1.4 7.6 2.8 2.1 2 0 0 2 2 2 0 Presenilin DUF2367 PF10164.9 OAJ19696.1 - 2.3 8.8 4.6 8.2 7.0 4.6 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Suf PF05843.14 OAJ19696.1 - 5.7 6.8 18.2 6.3 6.7 12.8 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Plasmodium_Vir PF05795.11 OAJ19696.1 - 6 6.2 6.9 2.6 7.3 0.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Peroxin-3 PF04882.12 OAJ19696.1 - 8 5.3 11.4 3.9 6.4 0.8 2.1 2 0 0 2 2 2 0 Peroxin-3 DUF3381 PF11861.8 OAJ19696.1 - 8.6 6.1 11.2 3.3 7.5 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Polyketide_cyc PF03364.20 OAJ19697.1 - 3.2e-25 88.8 0.1 6.8e-25 87.8 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAJ19697.1 - 0.00022 21.5 0.1 0.011 16.0 0.1 2.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cullin PF00888.22 OAJ19699.1 - 2.6e-138 462.4 0.0 6.4e-138 461.1 0.0 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ19699.1 - 1.6e-20 72.9 0.5 5.7e-20 71.1 0.5 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 OAJ19699.1 - 0.067 13.7 0.5 0.23 12.0 0.5 2.0 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal COX15-CtaA PF02628.15 OAJ19700.1 - 2.9e-88 296.1 3.6 4.5e-87 292.1 3.6 2.5 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein Anophelin PF10731.9 OAJ19700.1 - 0.3 11.0 1.1 0.91 9.4 1.1 1.8 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Cactin_mid PF10312.9 OAJ19701.1 - 8.3e-64 215.0 1.3 8.3e-64 215.0 1.3 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAJ19701.1 - 7.9e-57 190.6 6.8 1.3e-56 189.9 6.8 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein TRAPP PF04051.16 OAJ19702.1 - 6.9e-40 136.1 0.0 8.3e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Tyr-DNA_phospho PF06087.12 OAJ19703.1 - 1.3e-37 129.8 0.0 3.2e-26 92.2 0.0 2.7 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase CX9C PF16860.5 OAJ19704.1 - 1.8e-14 53.4 3.5 1.5e-10 40.9 0.9 2.4 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 OAJ19704.1 - 0.00027 21.2 2.3 0.021 15.2 0.2 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 OAJ19704.1 - 0.00075 19.5 7.0 0.045 13.8 0.7 3.0 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 OAJ19704.1 - 0.003 17.6 4.9 1.4 9.1 0.3 3.5 3 1 0 3 3 3 2 CHCH domain UPF0203 PF05254.12 OAJ19704.1 - 0.041 14.1 2.8 13 6.1 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) GCK PF07802.11 OAJ19704.1 - 0.047 14.1 0.9 4.1 7.9 0.2 2.2 2 0 0 2 2 2 0 GCK domain UCR_hinge PF02320.16 OAJ19704.1 - 0.19 11.9 7.7 5.9 7.2 0.2 3.4 1 1 2 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.13 OAJ19704.1 - 0.24 11.1 8.4 0.56 10.0 0.7 3.0 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Rotamase_2 PF13145.6 OAJ19705.1 - 0.0017 19.2 0.1 0.0034 18.2 0.1 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Fungal_trans PF04082.18 OAJ19706.1 - 2.6e-05 23.4 0.1 6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ19706.1 - 0.0071 16.4 6.7 0.33 11.1 0.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DSPc PF00782.20 OAJ19707.1 - 3.9e-06 26.7 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ19707.1 - 0.063 12.8 5.6 0.11 12.1 0.0 2.5 3 0 0 3 3 3 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAJ19707.1 - 0.17 12.0 1.7 0.94 9.6 0.0 2.6 3 0 0 3 3 3 0 Inositol hexakisphosphate Red1 PF07964.11 OAJ19707.1 - 0.67 8.1 5.3 1 7.5 5.3 1.2 1 0 0 1 1 1 0 Rec10 / Red1 ParA PF10609.9 OAJ19708.1 - 1.7e-80 270.0 0.0 1.6e-42 145.7 0.0 3.2 3 0 0 3 3 3 3 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ19708.1 - 1.3e-05 25.2 0.3 0.00097 19.2 0.2 2.8 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OAJ19708.1 - 0.0011 18.2 0.5 0.0021 17.3 0.5 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 OAJ19708.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 OAJ19708.1 - 0.027 14.3 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FXR_C1 PF16096.5 OAJ19708.1 - 0.028 14.6 0.7 0.028 14.6 0.7 1.7 2 0 0 2 2 1 0 Fragile X-related 1 protein C-terminal region 2 Fer4_NifH PF00142.18 OAJ19708.1 - 0.04 13.4 0.0 6 6.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 OAJ19708.1 - 0.046 12.9 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_31 PF13614.6 OAJ19708.1 - 0.058 13.3 1.0 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAJ19708.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 OAJ19708.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ19708.1 - 0.11 12.8 0.0 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Rsm22 PF09243.10 OAJ19708.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CENP-B_dimeris PF09026.10 OAJ19708.1 - 1.3 9.5 7.3 76 3.8 9.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MIP PF00230.20 OAJ19709.1 - 2.2e-46 158.4 6.2 3.1e-46 157.9 6.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Endosulfine PF04667.17 OAJ19723.1 - 1.4e-23 82.8 0.1 2.9e-23 81.8 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region ERG4_ERG24 PF01222.17 OAJ19724.1 - 4.5e-143 477.1 4.4 5.1e-143 476.9 4.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAJ19724.1 - 8.5e-05 22.2 0.1 8.5e-05 22.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAJ19724.1 - 0.00053 20.4 0.1 0.003 17.9 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 OAJ19724.1 - 0.003 17.9 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Myb_DNA-bind_4 PF13837.6 OAJ19725.1 - 0.0031 17.9 3.1 0.0047 17.3 0.3 2.9 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Ribosomal_S17e PF00833.18 OAJ19725.1 - 2.6 8.0 7.1 1.6 8.6 1.1 2.6 2 0 0 2 2 2 0 Ribosomal S17 Hid1 PF12722.7 OAJ19726.1 - 2.2 6.3 15.4 2.8 6.0 15.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TauD PF02668.16 OAJ19727.1 - 1.3e-48 166.1 3.0 1.7e-48 165.8 3.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SH3_1 PF00018.28 OAJ19728.1 - 9.8e-39 130.7 7.3 5.3e-16 58.0 0.2 4.6 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAJ19728.1 - 1.8e-37 126.9 10.2 5.6e-14 51.7 0.3 4.1 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 OAJ19728.1 - 1.3e-28 98.6 0.0 2.5e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 OAJ19728.1 - 6.2e-23 80.3 0.0 4.4e-09 35.9 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 OAJ19728.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 OAJ19728.1 - 0.00089 19.3 0.0 0.05 13.7 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 OAJ19728.1 - 0.002 18.4 2.4 0.075 13.3 0.1 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain Coilin_N PF15862.5 OAJ19728.1 - 4.1 7.2 26.9 0.078 12.8 0.3 3.7 3 0 0 3 3 3 0 Coilin N-terminus MFS_1 PF07690.16 OAJ19729.1 - 2.3e-27 95.9 26.0 2.3e-27 95.9 26.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Presenilin PF01080.17 OAJ19729.1 - 0.35 9.6 3.5 4.9 5.8 0.0 3.3 3 0 0 3 3 3 0 Presenilin DUF3899 PF13038.6 OAJ19729.1 - 0.88 10.1 5.0 2.3 8.8 1.7 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Zn_clus PF00172.18 OAJ19730.1 - 4e-07 30.0 9.1 6.9e-07 29.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ19730.1 - 0.0013 17.9 0.4 0.015 14.3 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain SANT_DAMP1_like PF16282.5 OAJ19731.1 - 0.19 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 WD40 PF00400.32 OAJ19732.1 - 2.8e-17 62.8 4.5 3.5e-07 30.8 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.25 OAJ19732.1 - 1.3e-13 51.0 0.0 9.9e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19732.1 - 4.1e-08 32.8 0.0 9.6e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 OAJ19732.1 - 1.2e-06 28.3 11.2 0.055 13.8 0.8 6.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OAJ19732.1 - 0.0019 18.5 3.6 1.6 9.2 0.2 4.0 4 2 0 4 4 4 2 HEAT repeats Cohesin_HEAT PF12765.7 OAJ19732.1 - 0.011 16.0 1.0 0.036 14.4 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 OAJ19732.1 - 0.072 13.1 0.2 11 6.0 0.1 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ABC_membrane PF00664.23 OAJ19734.1 - 9.1e-38 130.5 7.1 1.2e-37 130.1 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ19734.1 - 3.7e-33 114.9 0.0 9.7e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAJ19734.1 - 0.0024 17.3 0.5 0.55 9.6 0.0 2.6 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ19734.1 - 0.0041 17.0 0.1 0.1 12.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAJ19734.1 - 0.01 16.3 0.0 0.098 13.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAJ19734.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ19734.1 - 0.019 15.3 0.1 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ19734.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OAJ19734.1 - 0.053 13.8 0.2 0.26 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAJ19734.1 - 0.057 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 OAJ19734.1 - 0.07 12.8 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 OAJ19735.1 - 1.7e-59 201.4 0.0 1.1e-58 198.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19735.1 - 1.3e-27 96.7 0.0 4.2e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ19735.1 - 0.00036 20.0 0.1 0.6 9.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_C PF00433.24 OAJ19735.1 - 0.014 16.1 0.1 0.057 14.1 0.1 2.1 1 0 0 1 1 1 0 Protein kinase C terminal domain TGT_C1 PF14809.6 OAJ19735.1 - 0.026 14.8 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation Myc-LZ PF02344.15 OAJ19735.1 - 0.036 14.2 3.8 3.7 7.7 0.8 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain Kdo PF06293.14 OAJ19735.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ19735.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ19735.1 - 0.17 11.8 3.7 0.61 10.0 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Hamartin PF04388.12 OAJ19735.1 - 1.6 7.3 6.8 6.1 5.4 5.3 2.2 2 0 0 2 2 2 0 Hamartin protein TMEM154 PF15102.6 OAJ19736.1 - 0.75 9.7 0.0 0.75 9.7 0.0 3.5 4 0 0 4 4 4 0 TMEM154 protein family FAM176 PF14851.6 OAJ19737.1 - 0.95 9.1 3.5 2.3 7.9 3.5 1.6 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.18 OAJ19737.1 - 5.2 6.9 14.1 0.068 13.1 4.4 2.4 1 1 2 3 3 3 0 Myc amino-terminal region UPF0047 PF01894.17 OAJ19738.1 - 2.5e-38 130.8 0.0 3.2e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 YkuD_2 PF13645.6 OAJ19738.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain UL42 PF17638.2 OAJ19738.1 - 8.2 6.4 9.3 48 3.9 9.2 2.2 2 0 0 2 2 2 0 HCMV UL42 Yippee-Mis18 PF03226.14 OAJ19739.1 - 3.7e-14 52.8 0.2 4.1e-14 52.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAJ19739.1 - 0.036 14.3 0.4 0.057 13.7 0.4 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I Spindle_Spc25 PF08234.12 OAJ19740.1 - 1.7e-15 57.0 0.0 3.4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Macoilin PF09726.9 OAJ19740.1 - 0.015 13.9 4.9 0.017 13.7 4.9 1.1 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 OAJ19740.1 - 0.14 12.6 14.0 0.28 11.6 14.0 1.4 1 0 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 OAJ19740.1 - 0.26 9.2 2.6 0.32 8.9 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 OAJ19740.1 - 0.4 10.0 17.1 0.6 9.4 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OAJ19740.1 - 0.85 8.1 4.9 1.2 7.7 4.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 OAJ19740.1 - 1 8.2 14.8 2.9 6.7 14.8 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 OAJ19740.1 - 2.1 8.4 11.9 0.29 11.2 5.7 2.7 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 OAJ19740.1 - 3.8 7.7 9.8 4.4 7.5 0.4 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Mito_carr PF00153.27 OAJ19741.1 - 9.1e-43 144.1 0.2 1.2e-14 53.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ORMDL PF04061.14 OAJ19745.1 - 7.9e-53 177.9 3.4 9.9e-53 177.6 3.4 1.1 1 0 0 1 1 1 1 ORMDL family Carn_acyltransf PF00755.20 OAJ19746.1 - 1.2e-162 542.6 0.0 1.4e-162 542.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RskA PF10099.9 OAJ19747.1 - 0.066 13.5 30.2 0.042 14.1 8.1 3.1 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF4148 PF13663.6 OAJ19747.1 - 0.1 12.8 22.8 0.65 10.2 0.5 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Mito_fiss_reg PF05308.11 OAJ19747.1 - 0.82 9.7 4.5 0.15 12.1 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator SelP_N PF04592.14 OAJ19747.1 - 0.83 9.0 6.6 1.6 8.1 6.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region VIR_N PF15912.5 OAJ19747.1 - 2.6 7.6 6.5 4.2 6.9 6.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal TPR_12 PF13424.6 OAJ19763.1 - 1.2e-06 28.7 22.8 0.032 14.5 0.2 6.9 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19763.1 - 0.0016 18.4 16.5 4 7.8 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19763.1 - 0.0032 18.0 22.3 2.2 8.9 0.0 7.0 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19763.1 - 0.0038 17.8 17.3 13 6.5 0.1 6.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19763.1 - 0.0047 17.6 22.2 5.6 8.0 0.0 7.6 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19763.1 - 0.023 14.5 1.4 14 5.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ19763.1 - 0.027 14.5 2.0 0.53 10.4 0.1 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 OAJ19763.1 - 0.046 13.6 21.6 0.31 11.0 0.5 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19763.1 - 0.37 10.5 8.3 33 4.3 0.0 5.0 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 OAJ19763.1 - 0.66 10.5 10.6 50 4.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAJ19763.1 - 0.68 10.4 2.4 18 5.8 0.1 2.9 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Metallophos PF00149.28 OAJ19768.1 - 1.1e-10 42.3 0.1 4.1e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ19768.1 - 3.6e-05 24.0 0.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.23 OAJ19769.1 - 3.7e-56 190.8 0.0 4.7e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OAJ19769.1 - 0.00037 19.2 0.0 0.00047 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OAJ19769.1 - 0.004 16.8 0.0 0.0096 15.5 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAJ19769.1 - 0.0055 17.4 0.6 0.5 11.1 0.6 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 OAJ19769.1 - 0.021 15.1 0.0 0.059 13.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) Metalloenzyme PF01676.18 OAJ19769.1 - 0.024 14.0 0.0 0.62 9.4 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF1501 PF07394.12 OAJ19769.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MFS_1 PF07690.16 OAJ19770.1 - 5.1e-30 104.6 74.2 8.7e-25 87.4 44.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ19770.1 - 0.00014 20.9 32.8 0.00042 19.3 11.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.25 OAJ19772.1 - 1.4e-16 60.6 0.2 3.2e-07 30.0 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19772.1 - 1.9e-08 34.2 0.6 3.4e-05 23.5 0.0 2.5 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ19772.1 - 8.7e-06 25.8 0.1 2.9e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 OAJ19772.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family fn3_5 PF06280.12 OAJ19773.1 - 4.5e-09 37.0 0.0 8.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain Peptidase_S8 PF00082.22 OAJ19773.1 - 2.9e-05 23.5 0.2 5e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Subtilase family ASH PF15780.5 OAJ19773.1 - 0.0059 16.8 0.3 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF11 PF01345.18 OAJ19773.1 - 0.0071 16.6 0.8 0.024 15.0 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF11 Peptidase_S8 PF00082.22 OAJ19774.1 - 9.1e-19 67.8 0.2 1e-18 67.6 0.2 1.1 1 0 0 1 1 1 1 Subtilase family MHC_II_alpha PF00993.20 OAJ19774.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Peptidase_S8 PF00082.22 OAJ19775.1 - 3.8e-37 128.1 1.2 6.1e-37 127.5 1.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ19775.1 - 5.7e-08 33.5 0.0 1.3e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain TPR_19 PF14559.6 OAJ19776.1 - 0.047 14.2 1.7 22 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19776.1 - 0.056 13.5 0.5 44 4.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19776.1 - 0.13 13.2 9.7 61 4.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ19776.1 - 0.18 11.7 4.1 5.4 7.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peroxin-3 PF04882.12 OAJ19776.1 - 8.3 5.3 8.0 12 4.7 8.0 1.2 1 0 0 1 1 1 0 Peroxin-3 SNO PF01174.19 OAJ19778.1 - 4.6e-50 170.1 0.0 2.4e-39 135.2 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAJ19778.1 - 1.2e-08 34.7 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OAJ19778.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 OAJ19778.1 - 0.046 13.5 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family ABC_membrane_2 PF06472.15 OAJ19779.1 - 9e-94 313.8 5.1 1.3e-93 313.4 5.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ19779.1 - 4.3e-17 62.9 0.0 8.9e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 OAJ19779.1 - 0.002 17.9 0.1 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ19779.1 - 0.0048 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 OAJ19779.1 - 0.018 15.4 0.0 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 OAJ19779.1 - 0.024 15.1 0.1 0.05 14.0 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OAJ19779.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ19779.1 - 0.028 14.2 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ19779.1 - 0.037 14.5 0.3 0.093 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 OAJ19779.1 - 0.039 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAJ19779.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ19779.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 OAJ19779.1 - 0.23 8.9 0.0 0.45 8.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Stealth_CR2 PF11380.8 OAJ19780.1 - 9.8e-31 106.1 0.1 2.9e-30 104.6 0.1 1.8 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OAJ19780.1 - 2.9e-10 39.9 0.3 7.9e-10 38.5 0.3 1.8 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OAJ19780.1 - 1.6e-06 27.7 0.1 4.1e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 CMAS PF02353.20 OAJ19781.1 - 7.4e-62 209.1 0.0 2.3e-51 174.7 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ19781.1 - 6.8e-11 42.7 0.0 1.6e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ19781.1 - 1.6e-09 38.3 0.0 3.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ19781.1 - 1.7e-07 31.1 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ19781.1 - 4.4e-06 26.6 0.0 6.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ19781.1 - 0.00038 21.1 0.0 0.00089 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OAJ19781.1 - 0.0059 16.4 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein DUF938 PF06080.12 OAJ19781.1 - 0.012 15.4 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) PCMT PF01135.19 OAJ19781.1 - 0.061 13.1 0.0 0.39 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OAJ19781.1 - 0.12 12.1 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase TPR_2 PF07719.17 OAJ19782.1 - 0.00062 19.7 7.7 36 4.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19782.1 - 0.0028 18.1 12.8 0.19 12.2 0.0 5.6 7 1 1 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19782.1 - 0.0062 16.7 0.1 0.0062 16.7 0.1 4.5 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAJ19782.1 - 0.024 14.9 21.5 13 6.1 0.1 7.2 5 2 3 9 9 9 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ19782.1 - 0.049 13.7 1.6 4.7 7.3 0.0 4.3 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 OAJ19782.1 - 0.68 10.9 0.0 0.68 10.9 0.0 6.1 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ19782.1 - 9.7 6.2 6.0 37 4.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat APH PF01636.23 OAJ19784.1 - 0.0017 18.4 0.1 0.0035 17.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Presenilin PF01080.17 OAJ19787.1 - 1.5 7.5 33.7 1.7 7.3 33.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 OAJ19787.1 - 6.1 7.0 36.9 0.3 11.2 11.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Proteasome PF00227.26 OAJ19789.1 - 4.2e-44 150.3 0.0 5.8e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ19789.1 - 1e-08 34.7 0.4 1e-08 34.7 0.4 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Lipocalin_4 PF13648.6 OAJ19813.1 - 0.51 11.4 5.5 0.77 10.8 5.5 1.3 1 0 0 1 1 1 0 Lipocalin-like domain Methyltransf_12 PF08242.12 OAJ19814.1 - 2e-08 34.9 0.0 5.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ19814.1 - 2.1e-08 34.2 0.0 5e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ19814.1 - 6.9e-06 26.7 0.0 1.7e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ19814.1 - 3.9e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OAJ19814.1 - 0.013 16.2 0.0 0.028 15.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Med12 PF09497.10 OAJ19814.1 - 0.092 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 DUF2462 PF09495.10 OAJ19814.1 - 0.28 11.9 1.7 0.38 11.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Suf PF05843.14 OAJ19815.1 - 4.2e-82 276.5 0.6 1.2e-79 268.4 0.0 4.1 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAJ19815.1 - 8.8e-12 44.8 1.3 0.025 15.4 0.1 8.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19815.1 - 4.3e-07 30.3 0.0 0.43 11.1 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19815.1 - 0.027 14.7 0.0 0.35 11.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SDH_alpha PF03313.15 OAJ19816.1 - 9.7e-101 336.8 0.3 1.3e-100 336.4 0.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 OAJ19816.1 - 4.7e-55 186.2 0.0 1.2e-54 184.9 0.0 1.7 1 0 0 1 1 1 1 Serine dehydratase beta chain RRM_1 PF00076.22 OAJ19817.1 - 1.9e-13 50.0 0.0 2.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAJ19817.1 - 7.4e-07 29.6 1.2 7.4e-07 29.6 1.2 2.8 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 OAJ19817.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ19817.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif Mg_trans_NIPA PF05653.14 OAJ19818.1 - 4.3e-99 331.3 14.8 5.3e-99 331.1 14.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ19818.1 - 0.0015 18.7 4.2 0.0015 18.7 4.2 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF5336 PF17270.2 OAJ19818.1 - 2 8.0 6.3 10 5.7 0.2 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5336) PIRT PF15099.6 OAJ19818.1 - 4.5 6.9 6.2 8.2 6.0 2.7 2.8 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family LMF1 PF06762.14 OAJ19818.1 - 7.1 5.6 6.6 11 5.0 6.6 1.3 1 0 0 1 1 1 0 Lipase maturation factor WD40 PF00400.32 OAJ19819.1 - 7.3e-15 55.1 7.3 0.014 16.2 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19819.1 - 1.6e-10 41.2 0.0 3.6e-05 24.0 0.0 4.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAJ19819.1 - 0.00092 19.1 0.4 0.023 14.6 0.1 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 OAJ19819.1 - 0.11 11.4 0.0 20 4.0 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AKAP95 PF04988.12 OAJ19820.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Tom22 PF04281.13 OAJ19820.1 - 7.9 6.3 9.2 1.1 9.1 4.3 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 zf-C2H2 PF00096.26 OAJ19821.1 - 1.8e-09 37.5 8.8 0.00045 20.5 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ19821.1 - 8.4e-09 35.5 8.2 0.00093 19.8 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ19821.1 - 1.1e-05 25.7 0.8 1.1e-05 25.7 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 OAJ19821.1 - 0.00018 21.7 1.7 0.11 12.8 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 OAJ19821.1 - 0.0046 16.7 5.3 1.7 8.5 2.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 OAJ19821.1 - 0.018 15.1 5.2 1.4 9.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAJ19821.1 - 0.032 14.6 4.2 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Mucin PF01456.17 OAJ19822.1 - 6.8 6.7 23.2 7.9 6.5 22.9 1.3 1 1 0 1 1 1 0 Mucin-like glycoprotein Atg29_N PF18388.1 OAJ19823.1 - 0.073 12.9 0.2 14 5.6 0.3 2.3 2 0 0 2 2 2 0 Atg29 N-terminal domain V_ATPase_I PF01496.19 OAJ19824.1 - 3.3 5.5 5.2 4.1 5.2 5.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Rpn3_C PF08375.11 OAJ19825.1 - 4.6e-24 84.6 0.2 4.6e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAJ19825.1 - 3.8e-18 65.9 0.2 1e-17 64.6 0.2 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAJ19825.1 - 0.0094 16.0 2.2 0.11 12.6 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 OAJ19825.1 - 0.077 13.0 1.0 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TPR_16 PF13432.6 OAJ19825.1 - 0.2 12.3 6.7 0.98 10.1 0.5 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 OAJ19827.1 - 2.6e-50 171.3 0.0 1.9e-29 102.9 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19827.1 - 3.1e-21 75.8 0.6 1.6e-13 50.5 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ19827.1 - 2.3e-06 27.2 0.0 0.0044 16.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OAJ19827.1 - 0.0038 16.2 0.0 0.0057 15.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ19827.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ19827.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ19827.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF533 PF04391.12 OAJ19828.1 - 0.28 10.8 2.8 0.55 9.8 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) COesterase PF00135.28 OAJ19829.1 - 1.2e-61 209.2 0.0 2.9e-61 207.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ19829.1 - 1.4e-13 51.2 0.2 2.2e-12 47.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ19829.1 - 0.0064 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 OAJ19829.1 - 0.024 14.3 0.2 0.087 12.5 0.2 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 OAJ19829.1 - 0.17 12.5 2.9 0.21 12.2 0.1 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase family Peptidase_A22B PF04258.13 OAJ19831.1 - 1.3e-77 261.2 4.8 1.8e-77 260.7 4.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAJ19831.1 - 1.5e-07 31.2 1.3 3.7e-07 29.9 1.3 1.6 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CENP-B_dimeris PF09026.10 OAJ19831.1 - 7.6e-05 23.0 1.0 0.018 15.4 0.0 2.4 2 0 0 2 2 2 2 Centromere protein B dimerisation domain FAM176 PF14851.6 OAJ19831.1 - 0.002 17.8 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 FAM176 family Chol_subst-bind PF09129.11 OAJ19831.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding DcpS_C PF11969.8 OAJ19832.1 - 6.9e-10 39.4 0.3 0.0017 18.8 0.1 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ19832.1 - 7.5e-06 26.6 0.2 0.055 14.2 0.0 2.5 2 0 0 2 2 2 2 HIT domain zf-C2HE PF16278.5 OAJ19832.1 - 0.00016 22.1 0.0 0.00039 20.8 0.0 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L11_N PF03946.14 OAJ19833.1 - 2.9e-24 84.7 0.1 4.7e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ19833.1 - 1.9e-16 60.3 0.1 3.4e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.8 OAJ19833.1 - 0.036 14.3 1.9 0.06 13.6 1.9 1.3 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M URO-D PF01208.17 OAJ19834.1 - 2.5e-134 447.8 0.0 2.9e-134 447.6 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) zf-C2H2_11 PF16622.5 OAJ19835.1 - 0.00076 19.2 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 OAJ19835.1 - 0.096 13.2 0.0 0.096 13.2 0.0 3.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ19835.1 - 3.6 8.7 14.1 3 8.9 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger tRNA-synt_2b PF00587.25 OAJ19836.1 - 5e-36 124.3 0.0 8.1e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAJ19836.1 - 1.1e-17 64.2 3.6 1.1e-17 64.2 3.6 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 OAJ19836.1 - 0.076 13.0 5.0 0.16 12.0 5.0 1.5 1 0 0 1 1 1 0 FlxA-like protein TMPIT PF07851.13 OAJ19836.1 - 0.21 10.8 1.2 0.35 10.1 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cep57_MT_bd PF06657.13 OAJ19837.1 - 1.1e-10 41.8 1.6 1.1e-10 41.8 1.6 3.7 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 CTU2 PF10288.9 OAJ19837.1 - 0.12 12.7 1.4 0.88 9.8 1.4 2.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Pkinase PF00069.25 OAJ19838.1 - 2.2e-65 220.6 0.0 3.1e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19838.1 - 2.2e-42 145.2 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_2 PF07647.17 OAJ19838.1 - 1.7e-12 47.3 0.0 3.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ19838.1 - 3.3e-12 46.7 0.0 6.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 OAJ19838.1 - 3.4e-11 43.3 0.0 1.2e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 OAJ19838.1 - 5.8e-07 29.1 0.0 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_4 PF18017.1 OAJ19838.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 OAJ19838.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PPP4R2 PF09184.11 OAJ19838.1 - 0.39 10.3 9.3 1.5 8.3 9.3 2.0 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAJ19838.1 - 5.9 6.1 11.5 14 4.9 11.5 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAJ19838.1 - 8.3 4.5 8.8 13 3.8 8.8 1.2 1 0 0 1 1 1 0 Nop14-like family E1-E2_ATPase PF00122.20 OAJ19840.1 - 8.2e-39 133.0 2.0 8.2e-39 133.0 2.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ19840.1 - 2.2e-35 122.0 4.4 2.2e-35 122.0 4.4 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ19840.1 - 2.3e-18 67.2 0.2 1.4e-08 35.3 0.1 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ19840.1 - 3.3e-15 55.9 0.0 6.2e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ19840.1 - 1.3e-14 53.6 0.0 3.1e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 OAJ19840.1 - 0.036 13.9 0.0 0.036 13.9 0.0 3.1 4 0 0 4 4 4 0 Predicted membrane protein (DUF2157) UCH PF00443.29 OAJ19863.1 - 2.5e-28 99.3 0.0 6.2e-28 98.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ19863.1 - 4.8e-12 46.0 0.1 8.3e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAJ19863.1 - 0.0046 16.6 0.0 0.018 14.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 OAJ19863.1 - 0.12 12.2 0.4 0.22 11.3 0.4 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger MutS_V PF00488.21 OAJ19864.1 - 1.6e-59 201.2 0.0 7.3e-59 199.0 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ19864.1 - 3.3e-35 122.0 1.1 6.6e-35 121.1 1.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ19864.1 - 4e-24 85.0 0.0 1.2e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAJ19864.1 - 3.2e-10 40.4 0.0 7.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ19864.1 - 2.9e-08 34.0 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV SWIRM-assoc_2 PF16496.5 OAJ19864.1 - 2.9 6.7 5.0 1.4 7.7 0.9 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal zf_CCCH_4 PF18345.1 OAJ19865.1 - 1.5e-05 24.9 2.0 2.7e-05 24.1 2.0 1.5 1 0 0 1 1 1 1 Zinc finger domain Sin_N PF04801.13 OAJ19865.1 - 3.3e-05 23.3 4.4 3.3e-05 23.3 4.4 3.3 2 1 0 3 3 3 1 Sin-like protein conserved region zf-CCCH PF00642.24 OAJ19865.1 - 0.00014 21.7 1.4 0.00026 20.8 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAJ19865.1 - 0.0033 17.2 1.5 0.0054 16.5 1.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ19865.1 - 0.14 12.6 0.6 0.28 11.7 0.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Mito_carr PF00153.27 OAJ19866.1 - 4.5e-49 164.3 8.7 2.8e-17 62.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SLT PF01464.20 OAJ19867.1 - 0.0019 17.8 0.1 0.16 11.6 0.0 2.8 3 0 0 3 3 3 2 Transglycosylase SLT domain GCV_T PF01571.21 OAJ19868.1 - 2.3e-87 292.6 0.0 2.8e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAJ19868.1 - 5.9e-21 74.2 0.1 1.3e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 OAJ19868.1 - 0.0002 21.5 0.0 0.00044 20.4 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Thymidylate_kin PF02223.17 OAJ19869.1 - 5.4e-45 153.3 0.0 6.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 OAJ19869.1 - 5.5e-05 23.5 0.0 7.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ19869.1 - 0.0023 17.4 0.0 0.0043 16.5 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAJ19869.1 - 0.0033 17.6 0.1 0.038 14.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain PRK PF00485.18 OAJ19869.1 - 0.093 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family L51_S25_CI-B8 PF05047.16 OAJ19870.1 - 2.9e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SurE PF01975.17 OAJ19871.1 - 5.5e-34 117.7 0.1 5.5e-34 117.7 0.1 2.2 2 1 1 3 3 3 1 Survival protein SurE ABC2_membrane PF01061.24 OAJ19872.1 - 5.1e-39 133.9 18.5 7.4e-39 133.3 18.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ19872.1 - 8.6e-18 65.2 0.0 1.4e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 OAJ19872.1 - 5.1e-07 29.5 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OAJ19872.1 - 4.3e-05 23.1 0.0 7.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ19872.1 - 0.00091 19.1 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAJ19872.1 - 0.004 17.1 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAJ19872.1 - 0.0041 16.8 0.2 0.0087 15.8 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ19872.1 - 0.013 15.8 0.9 0.035 14.5 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OAJ19872.1 - 0.035 14.6 0.0 0.084 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ19872.1 - 0.05 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L27_C PF18471.1 OAJ19872.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Ribosomal L27 protein C-terminal domain AAA_23 PF13476.6 OAJ19872.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ19872.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ19872.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 OAJ19872.1 - 0.43 9.6 15.5 0.7 8.9 15.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 OAJ19874.1 - 2.2e-42 144.8 22.9 2.2e-42 144.8 22.9 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ19874.1 - 1.4e-40 139.0 0.0 1.9e-19 70.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAJ19874.1 - 2.8e-19 68.8 3.1 7.6e-19 67.4 0.0 2.4 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 OAJ19874.1 - 9.8e-12 45.3 0.2 2.4e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 OAJ19874.1 - 2.3e-06 27.8 1.1 0.077 13.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 OAJ19874.1 - 1.3e-05 24.8 0.6 0.012 15.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 OAJ19874.1 - 4.2e-05 22.8 16.2 4.2e-05 22.8 16.2 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 OAJ19874.1 - 0.00011 22.6 0.0 0.059 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ19874.1 - 0.0002 21.3 0.1 0.0056 16.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAJ19874.1 - 0.00027 20.6 0.1 0.0056 16.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ19874.1 - 0.00046 20.5 0.0 0.46 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ19874.1 - 0.00085 19.9 4.6 0.028 14.9 0.0 3.6 3 1 0 4 4 3 1 AAA domain AAA_30 PF13604.6 OAJ19874.1 - 0.0025 17.6 0.2 0.67 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAJ19874.1 - 0.0029 17.2 0.0 0.22 11.1 0.0 2.5 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 OAJ19874.1 - 0.0032 17.6 0.3 4.8 7.3 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OAJ19874.1 - 0.012 14.9 0.2 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 OAJ19874.1 - 0.013 14.9 0.0 5.8 6.3 0.0 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 OAJ19874.1 - 0.014 15.3 0.2 2.3 8.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 OAJ19874.1 - 0.027 14.3 0.0 0.077 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 OAJ19874.1 - 0.041 14.1 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ19874.1 - 0.043 14.2 0.0 10 6.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OAJ19874.1 - 0.07 13.6 0.1 22 5.5 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 OAJ19874.1 - 0.081 13.4 0.9 0.33 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 OAJ19874.1 - 0.15 11.3 0.1 2.7 7.3 0.0 2.4 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain Ploopntkinase3 PF18751.1 OAJ19874.1 - 0.17 11.8 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 OAJ19874.1 - 0.2 11.0 0.2 7.1 5.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 OAJ19874.1 - 0.84 10.1 4.5 0.92 9.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC2_membrane_2 PF12679.7 OAJ19874.1 - 2.5 7.3 10.5 5.4 6.2 10.5 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein DnaJ PF00226.31 OAJ19875.1 - 6e-21 74.3 1.2 2.3e-20 72.5 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 OAJ19875.1 - 1.1e-16 59.9 6.9 0.0008 19.1 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19875.1 - 1.9e-15 55.6 17.8 0.017 15.2 1.0 7.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ19875.1 - 2.1e-14 53.4 17.0 1.1e-05 25.4 0.7 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ19875.1 - 9.8e-14 50.7 1.9 0.0041 17.4 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ19875.1 - 2.9e-13 50.1 19.5 0.00055 20.4 0.2 5.7 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19875.1 - 1.6e-12 47.9 25.4 5.6e-05 23.7 0.7 5.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ19875.1 - 6.6e-11 42.1 25.1 0.021 15.6 3.6 6.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19875.1 - 1e-08 34.7 13.2 0.73 10.2 0.0 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19875.1 - 4.5e-06 26.2 11.9 0.0014 18.3 0.2 5.2 4 2 2 6 6 5 3 TPR repeat ANAPC3 PF12895.7 OAJ19875.1 - 7.2e-05 22.9 6.8 0.023 14.9 0.3 4.2 4 1 1 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ19875.1 - 0.00055 19.8 5.6 3.3 7.9 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 OAJ19875.1 - 0.0035 16.1 0.4 0.0035 16.1 0.4 3.3 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat TPR_20 PF14561.6 OAJ19875.1 - 0.0036 17.6 15.8 0.076 13.4 0.4 5.0 3 1 3 6 6 5 2 Tetratricopeptide repeat BTAD PF03704.17 OAJ19875.1 - 0.033 14.6 0.9 0.033 14.6 0.9 4.2 3 2 0 3 3 3 0 Bacterial transcriptional activator domain IF-2B PF01008.17 OAJ19875.1 - 0.035 13.3 0.6 0.066 12.4 0.6 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF3037 PF11236.8 OAJ19875.1 - 0.057 13.8 0.5 4.1 7.9 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Fis1_TPR_C PF14853.6 OAJ19875.1 - 0.11 12.5 5.7 0.46 10.6 0.1 4.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OAJ19875.1 - 0.12 12.6 15.2 2.7 8.4 0.4 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat APP_E2 PF12925.7 OAJ19875.1 - 0.37 10.5 5.9 9.8 5.8 2.0 2.9 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein AalphaY_MDB PF04611.12 OAJ19875.1 - 0.96 9.5 3.6 9.7 6.2 0.0 3.4 3 1 1 4 4 4 0 Mating type protein A alpha Y mating type dependent binding region Alkyl_sulf_dimr PF14863.6 OAJ19875.1 - 5.2 7.5 6.6 35 4.8 0.7 3.4 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 OAJ19875.1 - 8.5 7.3 18.6 18 6.2 0.0 7.2 8 1 0 8 8 7 0 Tetratricopeptide repeat Abhydro_lipase PF04083.16 OAJ19876.1 - 9.4e-15 53.9 0.0 2.1e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ19876.1 - 2.9e-07 30.4 0.1 7e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ19876.1 - 0.0019 17.5 0.0 0.0045 16.3 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PHP PF02811.19 OAJ19877.1 - 3.9e-08 33.8 0.1 1.8e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 PHP domain PIP5K PF01504.18 OAJ19878.1 - 1.1e-43 149.5 0.3 3.1e-33 115.2 0.0 3.3 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAJ19878.1 - 1.5e-27 96.4 0.3 2.4e-27 95.7 0.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAJ19878.1 - 2.4e-15 56.4 8.5 2.4e-15 56.4 8.5 1.8 2 0 0 2 2 2 1 FYVE zinc finger TFIIA PF03153.13 OAJ19878.1 - 0.0019 18.2 12.1 0.0019 18.2 12.1 4.2 4 1 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ19878.1 - 1.2 8.7 20.4 1 8.9 17.1 2.2 2 0 0 2 2 2 0 Spt20 family DUF3425 PF11905.8 OAJ19880.1 - 3.1e-09 36.9 1.2 1.9e-08 34.3 1.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAJ19880.1 - 8.5e-09 35.4 4.2 4.9e-08 33.0 4.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor TFIIA PF03153.13 OAJ19880.1 - 5.9e-05 23.2 14.0 5.9e-05 23.2 14.0 3.1 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 OAJ19880.1 - 2 8.8 17.4 0.41 11.0 3.6 3.5 3 0 0 3 3 3 0 Enhancer of polycomb-like FAM176 PF14851.6 OAJ19880.1 - 6.1 6.5 12.8 1.6 8.4 1.7 2.6 2 0 0 2 2 2 0 FAM176 family bZIP_1 PF00170.21 OAJ19881.1 - 3.9e-09 36.5 19.3 1.3e-07 31.6 6.8 3.0 2 1 1 3 3 3 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 OAJ19881.1 - 1.5e-06 28.1 4.8 1.5e-06 28.1 4.8 2.9 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.15 OAJ19881.1 - 0.0043 17.1 15.6 0.019 15.0 5.4 3.5 2 1 1 3 3 3 2 Basic region leucine zipper Fez1 PF06818.15 OAJ19881.1 - 0.0093 16.4 7.5 0.016 15.7 7.5 1.3 1 0 0 1 1 1 1 Fez1 HALZ PF02183.18 OAJ19881.1 - 0.012 15.8 0.5 0.025 14.8 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper HAUS-augmin3 PF14932.6 OAJ19881.1 - 0.71 9.4 7.6 1.1 8.7 7.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ZapB PF06005.12 OAJ19881.1 - 0.84 10.1 7.2 1 9.8 6.3 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DUF4472 PF14739.6 OAJ19881.1 - 1.2 9.9 8.6 2.5 8.9 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 OAJ19881.1 - 2.2 8.4 6.1 0.63 10.1 2.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 OAJ19881.1 - 4 6.2 10.2 6.3 5.6 10.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 OAJ19881.1 - 6.9 5.7 9.3 14 4.6 9.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Na_H_Exchanger PF00999.21 OAJ19882.1 - 9.1e-23 80.7 34.6 4.1e-15 55.5 6.5 4.0 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 OAJ19882.1 - 0.033 14.1 0.3 0.033 14.1 0.3 2.9 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system LIP PF03583.14 OAJ19883.1 - 9.1e-49 166.3 0.1 1.2e-48 165.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ19883.1 - 0.0019 17.7 0.3 0.1 12.1 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ19883.1 - 0.096 11.9 0.0 8 5.6 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SNF2_N PF00176.23 OAJ19884.1 - 4.3e-64 216.4 2.0 8.3e-64 215.5 2.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OAJ19884.1 - 6.6e-51 172.2 19.9 6.6e-51 172.2 19.9 3.5 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 OAJ19884.1 - 1.9e-16 60.4 0.0 4.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ19884.1 - 1.9e-06 28.0 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 OAJ19884.1 - 0.091 12.4 0.7 0.18 11.4 0.7 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain HDA2-3 PF11496.8 OAJ19884.1 - 0.14 11.3 0.0 0.14 11.3 0.0 2.6 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Paramyx_P_V_C PF03210.13 OAJ19884.1 - 6.8 6.4 6.5 1.5 8.6 1.5 2.4 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal MARVEL PF01284.23 OAJ19885.1 - 0.00028 20.9 20.2 0.00044 20.3 20.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain FAM209 PF15206.6 OAJ19885.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 FAM209 family COX4 PF02936.14 OAJ19886.1 - 9.9e-35 119.6 0.0 1.4e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV B12D PF06522.11 OAJ19886.1 - 0.11 12.3 0.5 0.31 10.9 0.5 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Peptidase_M20 PF01546.28 OAJ19887.1 - 2.1e-31 109.3 0.0 2.6e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ19887.1 - 2.3e-13 50.0 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain HAUS2 PF15003.6 OAJ19887.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 RhoGAP PF00620.27 OAJ19907.1 - 7.8e-46 155.7 0.0 1.4e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OAJ19907.1 - 4.4e-17 62.1 0.9 1.4e-16 60.5 0.2 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Apolipoprotein PF01442.18 OAJ19907.1 - 0.38 10.6 9.2 0.29 11.0 3.6 2.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain BBP1_C PF15272.6 OAJ19907.1 - 1.6 8.5 7.9 0.1 12.4 2.3 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DEAD PF00270.29 OAJ19908.1 - 4.2e-33 114.6 0.1 7.1e-33 113.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ19908.1 - 1.9e-29 102.2 0.0 4.3e-29 101.1 0.0 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.14 OAJ19908.1 - 6.6e-07 28.0 13.1 1.2e-06 27.2 13.1 1.3 1 0 0 1 1 1 1 CDC45-like protein Coilin_N PF15862.5 OAJ19908.1 - 0.00032 20.5 0.3 0.00032 20.5 0.3 2.8 2 1 1 3 3 3 1 Coilin N-terminus ResIII PF04851.15 OAJ19908.1 - 0.00033 20.7 1.7 0.00084 19.4 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Macoilin PF09726.9 OAJ19908.1 - 0.014 14.0 4.7 0.019 13.5 4.7 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 OAJ19908.1 - 0.025 13.4 10.6 0.05 12.5 10.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 OAJ19908.1 - 1.8 7.3 18.7 3 6.5 18.7 1.3 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 OAJ19908.1 - 1.8 6.7 39.9 2.9 6.0 39.9 1.2 1 0 0 1 1 1 0 Nop14-like family RPN6_N PF18055.1 OAJ19909.1 - 6.7e-42 142.5 3.3 6.1e-41 139.5 1.6 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAJ19909.1 - 1.7e-20 73.5 0.0 1e-19 70.9 0.0 2.3 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 OAJ19909.1 - 1.6e-13 50.1 0.7 3.8e-13 48.9 0.7 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Alkyl_sulf_dimr PF14863.6 OAJ19909.1 - 0.0015 18.9 1.0 0.035 14.6 0.4 3.0 3 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_16 PF13432.6 OAJ19909.1 - 0.0018 18.8 7.9 3.3 8.4 1.2 4.1 3 2 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ19909.1 - 0.01 16.0 0.6 2.1 8.6 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ19909.1 - 0.012 16.4 6.9 3.9 8.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ19909.1 - 0.027 15.1 5.8 15 6.5 0.1 5.3 4 2 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 OAJ19909.1 - 0.031 14.3 1.4 1.1 9.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ICAT PF06384.11 OAJ19909.1 - 0.12 12.6 0.4 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT TPR_19 PF14559.6 OAJ19909.1 - 0.15 12.6 11.3 0.084 13.4 1.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19909.1 - 0.66 10.2 7.7 53 4.3 0.2 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OAJ19910.1 - 2.2e-51 174.0 1.7 3.1e-51 173.5 1.7 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ19910.1 - 1.6e-14 54.3 0.0 4.4e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OAJ19910.1 - 0.048 13.6 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Pribosyltran PF00156.27 OAJ19911.1 - 5.6e-16 58.5 0.0 7.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ19911.1 - 0.0055 16.2 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase E1_dh PF00676.20 OAJ19913.1 - 8.3e-115 382.8 0.4 1e-114 382.5 0.4 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ19913.1 - 3.5e-05 23.2 0.1 7.9e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAJ19913.1 - 0.00055 19.8 4.7 0.001 18.9 1.9 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Piwi PF02171.17 OAJ19914.1 - 2.1e-70 237.4 0.0 3.2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAJ19914.1 - 1e-14 55.3 0.0 3.8e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAJ19914.1 - 3.7e-11 42.5 0.7 3.7e-11 42.5 0.7 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 OAJ19914.1 - 5.9e-08 32.6 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 OAJ19914.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute Mannosyl_trans PF05007.13 OAJ19915.1 - 3.6e-53 181.1 17.9 8.7e-33 114.3 12.3 3.5 2 1 1 3 3 3 3 Mannosyltransferase (PIG-M) WD40 PF00400.32 OAJ19916.1 - 1e-19 70.5 8.9 0.00047 20.9 0.0 6.4 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19916.1 - 1.7e-06 28.2 0.2 2 8.7 0.0 5.4 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 OAJ19916.1 - 0.0009 19.1 0.2 0.0015 18.4 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.12 OAJ19916.1 - 0.0033 17.3 0.7 58 3.8 0.0 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 OAJ19916.1 - 0.0036 17.2 0.1 0.59 10.0 0.0 3.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 OAJ19916.1 - 0.0045 16.6 0.0 2.3 7.8 0.0 2.7 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region DNA_pol_A_exo1 PF01612.20 OAJ19917.1 - 3.1e-37 128.0 0.1 4.5e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAJ19917.1 - 4.4e-19 69.0 0.2 2.4e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAJ19917.1 - 5e-10 39.2 0.1 9.8e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 HRDC domain RNase_HII PF01351.18 OAJ19918.1 - 1.2e-42 146.0 0.0 2.6e-37 128.6 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease HII Ras PF00071.22 OAJ19921.1 - 6.5e-54 181.9 0.0 7.5e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ19921.1 - 3e-21 75.9 0.0 4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ19921.1 - 5.4e-06 26.0 0.0 8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ19921.1 - 0.0025 17.4 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NAD_binding_2 PF03446.15 OAJ19923.1 - 1.2e-29 103.5 0.0 2.4e-29 102.5 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ19923.1 - 6.4e-29 100.7 0.0 1.1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Tubulin_2 PF13809.6 OAJ19923.1 - 0.084 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Tubulin like F420_oxidored PF03807.17 OAJ19923.1 - 0.096 13.3 0.0 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DCX PF03607.17 OAJ19923.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Doublecortin CDP-OH_P_transf PF01066.21 OAJ19924.1 - 6.7e-14 52.4 1.3 1e-13 51.8 0.3 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4718 PF15842.5 OAJ19924.1 - 0.16 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) EST1_DNA_bind PF10373.9 OAJ19925.1 - 1.3e-29 103.6 0.0 4.3e-22 78.9 0.0 3.2 2 1 1 3 3 3 3 Est1 DNA/RNA binding domain EST1 PF10374.9 OAJ19925.1 - 5.3e-16 59.5 0.3 2.5e-15 57.3 0.0 2.4 3 0 0 3 3 3 1 Telomerase activating protein Est1 Translin PF01997.16 OAJ19926.1 - 6.4e-43 147.1 0.1 7.9e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.9 OAJ19926.1 - 0.037 14.3 0.1 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spidroin_N PF16763.5 OAJ19926.1 - 0.091 12.8 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Mad3_BUB1_I PF08311.12 OAJ19927.1 - 4.9e-38 129.9 0.9 7.9e-38 129.2 0.9 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OAJ19927.1 - 8.7e-07 28.6 0.0 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain ICL PF00463.21 OAJ19928.1 - 3.3e-265 880.5 1.5 3.8e-265 880.3 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAJ19928.1 - 3.4e-09 36.5 0.0 6.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAJ19928.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Rhomboid_N PF12122.8 OAJ19928.1 - 0.11 12.7 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Ribo_biogen_C PF04034.13 OAJ19929.1 - 4.2e-48 162.3 0.0 5.8e-48 161.8 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAJ19929.1 - 7.1e-14 51.3 0.1 1.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SURF2 PF05477.11 OAJ19929.1 - 1.4 8.5 11.4 3.6 7.2 5.7 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) PDEase_II PF02112.15 OAJ19930.1 - 1.6e-39 135.9 0.0 6.7e-20 71.5 0.0 3.6 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 OAJ19930.1 - 0.06 12.8 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain LIM PF00412.22 OAJ19931.1 - 9.7e-16 57.8 8.8 0.00061 20.0 0.0 5.5 5 0 0 5 5 5 4 LIM domain CxC4 PF18717.1 OAJ19931.1 - 0.12 12.2 0.3 0.45 10.4 0.3 2.0 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases Phage_P2_GpE PF06528.12 OAJ19932.1 - 0.28 10.8 1.0 0.38 10.4 0.1 1.6 2 0 0 2 2 2 0 Phage P2 GpE CPSase_L_D2 PF02786.17 OAJ19948.1 - 7.5e-116 385.0 0.1 1.2e-83 279.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OAJ19948.1 - 6.2e-48 161.8 0.0 1.3e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAJ19948.1 - 3e-46 157.1 0.0 6.1e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 OAJ19948.1 - 7.1e-43 146.6 0.0 4.9e-42 143.9 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OAJ19948.1 - 4.6e-39 133.5 0.0 1e-38 132.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAJ19948.1 - 9.7e-32 110.2 0.0 2e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 OAJ19948.1 - 5.6e-18 65.2 0.1 4.5e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ19948.1 - 7e-16 58.3 0.0 1.4e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 OAJ19948.1 - 6.1e-11 42.4 0.0 2.3e-10 40.5 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 OAJ19948.1 - 1.2e-10 41.3 0.1 3e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 OAJ19948.1 - 3.5e-05 23.7 0.1 0.0025 17.6 0.0 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 OAJ19948.1 - 5.7e-05 23.2 0.0 0.32 11.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 OAJ19948.1 - 0.0076 16.0 0.0 0.13 12.1 0.0 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 OAJ19948.1 - 0.098 12.9 0.0 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 TrkA-N domain Glyoxalase_3 PF13468.6 OAJ19949.1 - 1.7e-22 80.4 1.6 4.4e-14 53.0 0.7 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain Longin PF13774.6 OAJ19950.1 - 2.1e-22 79.0 0.0 3.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAJ19950.1 - 1.5e-13 50.3 0.1 3.9e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Cu-oxidase_3 PF07732.15 OAJ19951.1 - 1.3e-30 105.8 9.1 2.7e-29 101.6 0.2 4.1 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ19951.1 - 1.2e-17 64.5 0.0 2.1e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ19951.1 - 1.7e-15 57.0 8.7 1.2e-11 44.5 3.6 3.5 2 2 0 2 2 2 2 Multicopper oxidase DNA_ligase_A_M PF01068.21 OAJ19952.1 - 1.7e-59 200.9 0.0 4e-59 199.7 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ19952.1 - 1.3e-46 159.1 0.0 3e-46 157.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAJ19952.1 - 1.2e-24 86.8 0.0 3.8e-24 85.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OAJ19952.1 - 0.00032 21.1 0.0 0.00099 19.4 0.0 1.9 2 1 0 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 OAJ19952.1 - 0.015 15.3 0.2 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain AAA_2 PF07724.14 OAJ19953.1 - 3.7e-31 108.5 0.0 3e-23 82.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAJ19953.1 - 2.6e-12 47.3 0.0 7.2e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAJ19953.1 - 3.1e-10 40.0 0.0 8.5e-10 38.6 0.0 1.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.6 OAJ19953.1 - 1.6e-05 25.2 0.2 0.00014 22.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAJ19953.1 - 0.00072 19.6 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM PF00493.23 OAJ19953.1 - 0.0016 17.6 0.0 0.0068 15.5 0.0 2.0 3 0 0 3 3 3 1 MCM P-loop domain AAA_16 PF13191.6 OAJ19953.1 - 0.0038 17.6 0.0 0.017 15.5 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OAJ19953.1 - 0.019 15.5 0.0 0.078 13.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 OAJ19953.1 - 0.02 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 OAJ19953.1 - 0.021 14.2 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ19953.1 - 0.022 14.9 1.0 0.042 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ19953.1 - 0.022 14.7 0.0 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 OAJ19953.1 - 0.024 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ19953.1 - 0.046 13.1 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TsaE PF02367.17 OAJ19953.1 - 0.058 13.4 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 OAJ19953.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 OAJ19953.1 - 0.078 13.0 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ19953.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Macoilin PF09726.9 OAJ19953.1 - 1.1 7.8 9.3 2.2 6.7 9.3 1.5 1 0 0 1 1 1 0 Macoilin family ABC_tran PF00005.27 OAJ19954.1 - 3.1e-15 56.9 0.0 1.1e-14 55.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ19954.1 - 2.2e-09 37.6 1.1 0.0021 17.9 0.1 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ19954.1 - 0.0015 18.2 0.0 0.0053 16.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ19954.1 - 0.047 14.1 0.1 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 OAJ19954.1 - 0.05 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ19954.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 OAJ19954.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ19954.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAJ19954.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 OAJ19955.1 - 4.6e-69 232.2 3.6 6.6e-67 225.2 3.6 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ19955.1 - 4e-19 69.0 0.7 1.7e-18 67.0 0.2 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ19955.1 - 9.3e-15 55.7 18.0 9.3e-15 55.7 18.0 7.1 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OAJ19955.1 - 1.8e-09 37.8 16.9 3.7e-05 23.7 0.3 4.1 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ19955.1 - 4e-05 23.3 0.0 0.00014 21.5 0.0 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 OAJ19955.1 - 0.0011 17.9 18.2 0.0011 17.9 18.2 7.3 2 2 5 7 7 7 2 Spc7 kinetochore protein FliJ PF02050.16 OAJ19955.1 - 0.0057 16.9 12.3 0.0057 16.9 12.3 8.5 4 2 3 8 8 8 1 Flagellar FliJ protein ABC_tran PF00005.27 OAJ19955.1 - 0.41 11.2 0.0 0.41 11.2 0.0 6.5 3 2 1 4 4 4 0 ABC transporter IGR PF09597.10 OAJ19955.1 - 0.42 10.8 1.9 0.6 10.3 0.2 2.3 2 0 0 2 2 2 0 IGR protein motif Rbsn PF11464.8 OAJ19955.1 - 9.4 6.1 19.8 5.1 6.9 0.4 5.4 4 0 0 4 4 4 0 Rabenosyn Rab binding domain SRP54 PF00448.22 OAJ19956.1 - 1.8e-74 249.6 0.1 1.8e-74 249.6 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAJ19956.1 - 2e-28 98.9 0.1 2e-28 98.9 0.1 3.8 3 1 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 OAJ19956.1 - 2.5e-16 59.7 2.2 5.4e-16 58.6 2.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 OAJ19956.1 - 9.8e-05 22.0 0.8 0.0016 18.0 0.8 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAJ19956.1 - 0.0017 18.6 0.0 0.0042 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ19956.1 - 0.0084 16.5 0.0 0.0084 16.5 0.0 3.2 4 0 0 4 4 3 1 AAA domain APS_kinase PF01583.20 OAJ19956.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 OAJ19956.1 - 0.032 14.5 0.0 0.097 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ19956.1 - 0.047 14.1 1.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OAJ19956.1 - 0.064 13.0 0.2 0.064 13.0 0.2 2.8 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAJ19956.1 - 0.099 12.7 0.2 0.44 10.6 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 OAJ19956.1 - 0.17 11.9 0.8 2.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Lipase_chap PF03280.14 OAJ19956.1 - 9.7 6.1 10.2 1.7 8.5 0.3 2.7 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein GMC_oxred_N PF00732.19 OAJ19957.1 - 3.2e-38 131.8 0.0 5.5e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ19957.1 - 2.4e-20 73.5 1.6 8.4e-20 71.8 0.7 2.3 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ19957.1 - 1.1e-08 34.6 0.7 1.9e-05 23.9 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ19957.1 - 4.2e-05 23.7 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ19957.1 - 6.4e-05 22.4 0.3 0.00011 21.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ19957.1 - 0.00021 21.0 0.5 0.0074 15.9 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ19957.1 - 0.0012 18.2 0.3 0.0036 16.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ19957.1 - 0.012 15.0 1.3 0.017 14.5 1.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ19957.1 - 0.02 13.6 0.2 0.031 13.0 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAJ19957.1 - 0.027 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ19957.1 - 0.048 12.7 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAJ19957.1 - 0.052 13.2 0.4 0.092 12.4 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAJ19957.1 - 0.15 11.3 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ19957.1 - 0.19 10.8 0.1 0.27 10.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC2_membrane PF01061.24 OAJ19958.1 - 6.6e-68 228.3 55.6 1.3e-39 135.8 18.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ19958.1 - 4.9e-35 121.0 0.0 1.4e-17 64.5 0.0 3.2 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAJ19958.1 - 2.4e-31 107.5 1.2 2.8e-28 97.6 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 OAJ19958.1 - 2.1e-11 44.3 0.1 6.1e-11 42.8 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 OAJ19958.1 - 6.8e-06 26.1 0.0 4.9e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAJ19958.1 - 9.2e-06 26.1 1.3 0.00026 21.4 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 OAJ19958.1 - 0.0014 18.3 0.1 0.0059 16.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ19958.1 - 0.0017 18.6 0.2 0.11 12.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OAJ19958.1 - 0.0098 15.8 0.0 0.099 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 OAJ19958.1 - 0.016 15.2 0.2 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 OAJ19958.1 - 0.02 15.0 0.4 0.23 11.5 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 OAJ19958.1 - 0.036 13.9 0.1 4.3 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ19958.1 - 0.053 13.3 0.3 0.46 10.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ19958.1 - 0.08 13.5 0.0 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAJ19958.1 - 0.13 12.0 1.0 0.58 9.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ19958.1 - 0.2 11.2 1.6 0.47 10.0 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OAJ19958.1 - 0.21 11.3 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 OAJ19959.1 - 0.0041 17.2 43.8 0.013 15.5 20.9 3.5 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Macoilin PF09726.9 OAJ19959.1 - 0.27 9.8 23.3 0.067 11.7 14.2 2.4 2 0 0 2 2 2 0 Macoilin family PKcGMP_CC PF16808.5 OAJ19959.1 - 0.62 10.0 0.0 0.62 10.0 0.0 4.1 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_S21e PF01249.18 OAJ19960.1 - 3.6e-35 119.9 0.0 4e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FliMN_C PF01052.20 OAJ19960.1 - 0.044 13.8 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term Tubulin PF00091.25 OAJ19961.1 - 1.2e-71 241.0 0.0 3.3e-71 239.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ19961.1 - 3e-42 143.8 0.3 4.6e-42 143.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ19961.1 - 8.7e-07 29.3 0.0 2.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ19961.1 - 0.00032 20.4 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ19961.1 - 0.001 18.4 0.0 0.0073 15.5 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Lactonase PF10282.9 OAJ19961.1 - 0.11 11.7 0.0 1.7 7.8 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Pirin PF02678.16 OAJ19962.1 - 1.1e-28 99.3 0.4 2e-28 98.5 0.4 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 OAJ19962.1 - 3.3e-09 36.3 1.2 8.2e-08 31.9 0.2 2.6 2 0 0 2 2 2 1 Cupin domain Sybindin PF04099.12 OAJ19963.1 - 6.8e-40 136.3 0.0 7.4e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAJ19963.1 - 1.3e-07 31.8 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NRDD PF13597.6 OAJ19963.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DPBB_1 PF03330.18 OAJ19964.1 - 1.8e-06 28.1 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ19964.1 - 0.0025 17.7 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Barwin family Raftlin PF15250.6 OAJ19964.1 - 3 6.5 6.3 0.73 8.5 2.7 1.7 2 0 0 2 2 2 0 Raftlin Kinesin PF00225.23 OAJ19965.1 - 1e-109 366.5 0.0 1e-109 366.5 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ19965.1 - 1.2e-26 93.4 0.0 5.5e-26 91.3 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 OAJ19965.1 - 0.00012 22.4 15.9 0.00012 22.4 15.9 4.8 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Sox_N PF12444.8 OAJ19965.1 - 0.032 15.4 2.6 0.29 12.3 0.0 3.7 3 0 0 3 3 3 0 Sox developmental protein N terminal DarT PF14487.6 OAJ19965.1 - 0.27 11.1 3.6 1.1 9.1 0.9 2.5 2 0 0 2 2 2 0 ssDNA thymidine ADP-ribosyltransferase, DarT HOOK PF05622.12 OAJ19965.1 - 10 4.2 82.2 0.16 10.1 24.4 3.2 1 1 1 2 2 2 0 HOOK protein TIG PF01833.24 OAJ19966.1 - 2.6e-13 49.8 0.8 1.7e-11 44.0 1.4 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 OAJ19966.1 - 9.5e-11 42.0 0.9 2.3e-10 40.8 0.9 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ19966.1 - 1.2e-09 38.2 0.3 4e-09 36.6 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ19966.1 - 2.6e-08 33.5 0.4 0.0022 18.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 OAJ19966.1 - 4.4e-08 33.6 0.0 8.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ19966.1 - 4.5e-07 30.0 1.6 0.02 15.3 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat HSA PF07529.13 OAJ19967.1 - 1.3e-10 41.4 3.3 1.3e-10 41.4 3.3 4.6 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 OAJ19967.1 - 1.7e-09 37.8 0.0 4.4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ19967.1 - 2.2e-05 24.5 0.0 4.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ19967.1 - 0.00052 20.2 0.2 0.0015 18.7 0.2 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 FAD_binding_7 PF03441.14 OAJ19968.1 - 2.4e-54 183.9 0.5 3.8e-54 183.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ19968.1 - 3.9e-19 69.2 0.0 6.9e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Prefoldin PF02996.17 OAJ19969.1 - 7e-27 93.7 0.1 8.9e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAJ19969.1 - 0.0043 17.0 0.1 0.32 11.0 0.1 2.2 2 0 0 2 2 2 2 Prefoldin subunit DUF1192 PF06698.11 OAJ19969.1 - 0.1 12.7 0.8 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 OAJ19969.1 - 0.12 12.4 0.1 5.2 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GATA PF00320.27 OAJ19970.1 - 8.2e-27 92.5 21.2 4.1e-14 51.9 4.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 OAJ19970.1 - 6.3e-10 38.7 0.6 1.4e-09 37.6 0.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 OAJ19970.1 - 0.0013 18.2 7.2 0.039 13.5 1.5 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Inj_translocase PF16928.5 OAJ19970.1 - 0.075 12.5 0.1 0.075 12.5 0.1 3.3 4 0 0 4 4 4 0 DNA/protein translocase of phage P22 injectosome Zn-ribbon_8 PF09723.10 OAJ19970.1 - 0.2 11.8 7.1 0.54 10.4 0.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OAJ19970.1 - 0.27 11.2 7.8 4.8 7.2 0.7 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 OAJ19970.1 - 0.45 10.6 8.6 14 5.8 8.8 2.7 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 OAJ19970.1 - 0.97 9.6 11.4 0.49 10.6 0.6 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-piccolo PF05715.13 OAJ19970.1 - 1.5 9.0 11.4 2.5 8.3 1.3 3.4 2 1 1 3 3 3 0 Piccolo Zn-finger eIF-5_eIF-2B PF01873.17 OAJ19970.1 - 4.5 7.2 9.6 2.2 8.2 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 CFEM PF05730.11 OAJ19971.1 - 1.3e-08 34.8 11.9 2.3e-08 34.0 11.9 1.4 1 0 0 1 1 1 1 CFEM domain Lysine_decarbox PF03641.14 OAJ19972.1 - 4.4e-32 111.0 0.0 5.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAJ19972.1 - 2.3e-10 40.3 1.1 7.3e-10 38.7 1.1 1.9 1 1 0 1 1 1 1 SLOG cluster4 family HMG-CoA_red PF00368.18 OAJ19973.1 - 8.3e-141 469.2 8.1 1.3e-140 468.6 8.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 OAJ19973.1 - 1.8e-20 73.3 0.7 2.4e-09 37.2 0.2 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ19973.1 - 7.2e-06 24.4 2.1 0.0044 15.2 0.0 2.2 2 0 0 2 2 2 2 Patched family HPIH PF13323.6 OAJ19973.1 - 0.056 13.3 3.2 0.24 11.3 3.1 2.2 1 1 0 1 1 1 0 N-terminal domain with HPIH motif ubiquitin PF00240.23 OAJ19974.1 - 6.7e-34 115.5 0.7 9.4e-34 115.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ19974.1 - 4.7e-16 58.4 0.8 7.2e-16 57.8 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 OAJ19974.1 - 8.4e-10 38.7 5.3 1.4e-09 38.0 5.3 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 OAJ19974.1 - 3.2e-05 24.3 0.2 0.00012 22.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ19974.1 - 0.0044 17.1 0.4 0.021 14.9 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ19974.1 - 0.0062 16.5 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ19974.1 - 0.0072 16.7 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OAJ19974.1 - 0.022 15.3 0.0 0.025 15.1 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ19974.1 - 0.023 14.8 1.1 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ19974.1 - 0.12 12.2 0.8 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Pet191_N PF10203.9 OAJ19975.1 - 4.3e-24 84.6 3.5 5e-24 84.4 3.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CCT PF06203.14 OAJ19975.1 - 0.07 13.2 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 CCT motif G-patch_2 PF12656.7 OAJ19994.1 - 3.2e-22 78.4 1.1 9.1e-22 76.9 1.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 OAJ19994.1 - 5.7e-06 26.1 3.7 1.1e-05 25.2 3.7 1.5 1 0 0 1 1 1 1 G-patch domain Raftlin PF15250.6 OAJ19994.1 - 0.046 12.5 3.6 0.061 12.1 3.6 1.1 1 0 0 1 1 1 0 Raftlin Med13_C PF06333.12 OAJ19995.1 - 1e-19 71.0 4.6 1e-19 71.0 4.6 4.2 3 1 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 OAJ19995.1 - 1.1 9.0 5.7 13 5.4 0.0 3.8 3 1 1 4 4 4 0 MID domain of medPIWI zf-RING_UBOX PF13445.6 OAJ19996.1 - 2.6e-08 33.8 1.5 2.6e-08 33.8 1.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ19996.1 - 1.5e-07 31.1 3.3 1.9e-06 27.6 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ19996.1 - 3.4e-07 30.0 1.3 3.4e-07 30.0 1.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ19996.1 - 2.6e-06 27.1 1.3 2.6e-06 27.1 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ19996.1 - 2.8e-06 27.6 4.8 5.8e-06 26.5 0.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ19996.1 - 9.5e-05 22.5 2.0 9.5e-05 22.5 2.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ19996.1 - 9.9e-05 22.1 4.4 0.0011 18.8 2.0 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1644 PF07800.12 OAJ19996.1 - 0.00012 22.2 0.7 0.09 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 OAJ19996.1 - 0.00019 21.3 1.5 0.00019 21.3 1.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 OAJ19996.1 - 0.33 10.7 2.5 0.67 9.8 2.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_clus PF00172.18 OAJ19997.1 - 2.9e-07 30.5 10.7 4.5e-07 29.9 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3684 PF12449.8 OAJ19998.1 - 1.6e-293 976.6 0.0 1.3e-275 917.4 0.0 4.0 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) WLM PF08325.10 OAJ19998.1 - 0.97 9.5 3.0 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 WLM domain Redoxin PF08534.10 OAJ19999.1 - 5.8e-27 94.2 0.0 6.6e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ19999.1 - 1.8e-09 37.5 0.0 2.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Lyase_1 PF00206.20 OAJ20001.1 - 3.7e-22 79.1 0.0 5.8e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAJ20001.1 - 1.5e-17 63.8 0.0 3.6e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus PX PF00787.24 OAJ20002.1 - 6.9e-17 61.5 0.1 1.6e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 OAJ20002.1 - 6e-07 29.2 0.2 1.3e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DivIC PF04977.15 OAJ20002.1 - 1.6 8.6 6.5 3.6 7.4 6.5 1.5 1 0 0 1 1 1 0 Septum formation initiator SUIM_assoc PF16619.5 OAJ20002.1 - 2.1 8.4 18.0 0.14 12.3 9.7 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF2235 PF09994.9 OAJ20003.1 - 5.1e-83 278.8 0.0 7.8e-83 278.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 OAJ20003.1 - 0.029 14.3 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sugar_tr PF00083.24 OAJ20005.1 - 0.00047 19.1 0.3 0.00059 18.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 OAJ20006.1 - 1.3e-74 251.8 16.4 1.4e-74 251.6 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20006.1 - 0.038 12.9 35.1 0.38 9.6 22.7 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily DHHA2 PF02833.14 OAJ20007.1 - 8.6e-19 68.1 0.1 3.4e-18 66.2 0.1 1.9 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 OAJ20007.1 - 7.4e-11 42.2 0.0 4.2e-09 36.6 0.0 2.3 1 1 1 2 2 2 1 DHH family DUF3328 PF11807.8 OAJ20007.1 - 0.06 13.1 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) An_peroxidase PF03098.15 OAJ20008.1 - 7.6e-39 133.7 0.1 5e-24 84.8 0.1 4.0 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAJ20008.1 - 7.7e-12 44.7 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MKT1_C PF12246.8 OAJ20009.1 - 5.1e-73 245.3 0.0 1.7e-72 243.6 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 OAJ20009.1 - 2.3e-22 79.2 0.0 5.6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 OAJ20009.1 - 8.9e-06 26.1 0.0 2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PB1 PF00564.24 OAJ20010.1 - 0.00011 22.1 0.0 0.00011 22.1 0.0 2.0 3 0 0 3 3 3 1 PB1 domain Methyltransf_15 PF09445.10 OAJ20011.1 - 7.7e-34 116.7 0.0 2.5e-26 92.2 0.0 2.3 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAJ20011.1 - 3.3e-08 33.5 0.0 2e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OAJ20011.1 - 7.9e-07 29.7 0.1 7e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ20011.1 - 7.7e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ20011.1 - 8.5e-05 22.3 0.0 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 RrnaAD PF00398.20 OAJ20011.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0020 PF01170.18 OAJ20011.1 - 0.002 17.9 0.1 0.0096 15.6 0.0 2.1 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 OAJ20011.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 OAJ20011.1 - 0.0064 17.1 0.1 0.023 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TRM PF02005.16 OAJ20011.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 OAJ20011.1 - 0.041 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase BUD22 PF09073.10 OAJ20011.1 - 0.65 9.3 41.4 2.3 7.5 0.5 2.1 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 OAJ20012.1 - 1.9e-23 83.2 0.0 2.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20012.1 - 5e-12 45.7 0.0 7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ20012.1 - 3.5e-08 32.7 1.1 4.3e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF3915 PF13054.6 OAJ20012.1 - 0.61 10.1 5.6 1.4 9.0 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM76 PF16046.5 OAJ20012.1 - 1.6 8.1 5.0 2.5 7.4 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein Rrn6 PF10214.9 OAJ20012.1 - 1.9 6.9 5.9 3.1 6.2 5.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DHO_dh PF01180.21 OAJ20014.1 - 3.8e-91 305.3 0.0 2.6e-90 302.6 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase C1ORF64 PF15547.6 OAJ20014.1 - 2.5 8.6 46.5 0.88 10.0 2.6 6.6 1 1 6 7 7 7 0 Steroid receptor-associated and regulated protein Zn_clus PF00172.18 OAJ20015.1 - 2.7e-07 30.6 11.2 2.7e-07 30.6 11.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 OAJ20016.1 - 4.5e-46 156.7 0.4 5.9e-43 146.6 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAJ20016.1 - 4.1e-14 51.9 0.1 7.8e-14 51.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribophorin_II PF05817.14 OAJ20016.1 - 0.015 13.8 0.1 0.018 13.7 0.1 1.4 1 1 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Sugar_tr PF00083.24 OAJ20017.1 - 6.6e-33 114.2 20.7 4e-32 111.7 20.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20017.1 - 2.8e-29 102.2 39.6 6.5e-29 100.9 38.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1516 PF07457.11 OAJ20017.1 - 0.72 10.1 6.6 6.5 7.0 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) DDE_1 PF03184.19 OAJ20018.1 - 1.5e-47 161.5 0.1 3.1e-47 160.5 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ20018.1 - 1.6e-11 44.1 1.5 3.8e-11 42.8 0.6 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 OAJ20018.1 - 2.8e-05 23.7 0.2 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DDE_3 PF13358.6 OAJ20018.1 - 0.00066 19.5 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ20018.1 - 0.056 14.1 0.2 0.056 14.1 0.2 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HA2 PF04408.23 OAJ20035.1 - 5.7e-15 55.5 0.6 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ20035.1 - 1.4e-08 35.0 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ20035.1 - 7.8e-08 32.6 0.0 6.5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ20035.1 - 0.0035 17.6 0.9 0.3 11.4 0.5 3.3 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 OAJ20035.1 - 0.0039 16.3 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.29 OAJ20035.1 - 0.024 14.4 0.1 2 8.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 OAJ20035.1 - 0.077 13.0 0.1 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 OAJ20035.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Hexokinase_1 PF00349.21 OAJ20037.1 - 3.9e-70 235.8 0.0 5.5e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 OAJ20037.1 - 3e-69 233.1 0.0 3.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase zf-C2H2 PF00096.26 OAJ20038.1 - 2.4e-19 68.6 70.2 0.044 14.2 4.9 10.5 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ20038.1 - 1.9e-12 46.9 64.5 0.02 15.7 0.3 10.6 10 0 0 10 10 10 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ20038.1 - 0.00028 21.1 19.9 2.4 8.6 0.0 6.9 7 0 0 7 7 7 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAJ20038.1 - 0.00068 20.2 28.5 0.75 10.5 1.1 7.0 6 1 1 7 7 7 3 FOXP coiled-coil domain TFIIA PF03153.13 OAJ20038.1 - 0.0047 17.0 2.0 0.0047 17.0 2.0 3.1 2 1 0 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 OAJ20038.1 - 0.012 16.1 0.0 0.012 16.1 0.0 11.9 13 0 0 13 13 13 0 Zinc-finger double domain zf_ZIC PF18366.1 OAJ20038.1 - 0.013 15.6 10.8 0.65 10.2 0.0 5.3 6 0 0 6 6 6 0 Zic proteins zinc finger domain Zn-C2H2_12 PF18112.1 OAJ20038.1 - 0.014 15.8 0.0 21 5.7 0.0 3.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_8 PF15909.5 OAJ20038.1 - 0.015 15.6 18.8 2.1 8.7 1.6 5.6 3 2 1 5 5 5 0 C2H2-type zinc ribbon RNA_pol_3_Rpc31 PF11705.8 OAJ20038.1 - 0.021 15.1 0.5 0.021 15.1 0.5 4.5 4 0 0 4 4 4 0 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2_aberr PF17017.5 OAJ20038.1 - 0.076 13.2 4.6 18 5.4 0.1 5.2 5 1 1 6 6 6 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 OAJ20038.1 - 3.6 7.7 26.8 0.76 9.8 0.2 7.1 8 0 0 8 8 7 0 C2H2-type zinc finger E1-E2_ATPase PF00122.20 OAJ20040.1 - 1.1e-11 44.6 0.4 7.3e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_N PF00690.26 OAJ20040.1 - 9e-11 41.3 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Peptidase_M50B PF13398.6 OAJ20040.1 - 0.0032 17.1 0.8 0.0044 16.7 0.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Trp_oprn_chp PF09534.10 OAJ20040.1 - 0.021 14.6 1.0 0.03 14.1 1.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF5421 PF17458.2 OAJ20040.1 - 0.064 12.6 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Chitin_synth_1 PF01644.17 OAJ20041.1 - 3.4e-70 235.2 0.0 6.4e-70 234.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ20041.1 - 1.8e-27 95.1 0.0 3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ20041.1 - 3.7e-24 85.2 1.7 7.3e-17 61.2 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ20041.1 - 1.2e-08 35.1 6.3 2.9e-08 33.9 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 SK_channel PF03530.14 OAJ20041.1 - 0.45 10.5 2.2 1.1 9.3 2.2 1.5 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Ysc84 PF04366.12 OAJ20042.1 - 2.9e-42 143.5 1.5 3e-41 140.2 0.2 2.1 2 0 0 2 2 2 2 Las17-binding protein actin regulator BBE PF08031.12 OAJ20043.1 - 2.3e-12 46.8 0.5 4.1e-12 46.0 0.5 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAJ20043.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Mago-bind PF09282.10 OAJ20044.1 - 6.4e-14 51.5 2.4 6.4e-14 51.5 2.4 2.0 2 0 0 2 2 2 1 Mago binding SOG2 PF10428.9 OAJ20044.1 - 2 7.5 10.4 2.3 7.3 10.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DNA_pol_phi PF04931.13 OAJ20044.1 - 2.4 6.2 6.9 3 5.8 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Apt1 PF10351.9 OAJ20044.1 - 3.9 6.2 5.6 4.2 6.1 5.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF3_subunit PF08597.10 OAJ20044.1 - 8.8 6.2 19.6 38 4.1 19.6 2.0 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit ABC1 PF03109.16 OAJ20045.1 - 1e-17 64.4 0.1 1.2e-07 31.9 0.0 2.7 3 0 0 3 3 3 2 ABC1 family FA_desaturase PF00487.24 OAJ20046.1 - 5.6e-27 95.2 14.2 2.9e-15 56.8 2.4 2.5 2 0 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 OAJ20046.1 - 1.9e-07 31.1 0.0 4.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2_aberr PF17017.5 OAJ20047.1 - 7.5e-05 22.9 5.0 0.071 13.2 0.2 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAJ20047.1 - 0.23 12.0 8.5 5 7.8 1.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_ZIC PF18366.1 OAJ20047.1 - 0.5 10.5 1.9 1 9.5 0.2 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 OAJ20047.1 - 8.2 7.6 13.3 5.3 8.2 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CMAS PF02353.20 OAJ20048.1 - 1.2e-61 208.4 0.1 1.5e-61 208.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ20048.1 - 2.2e-13 50.7 0.0 5.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ20048.1 - 9e-12 45.1 0.0 1.7e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ20048.1 - 2.3e-11 44.2 0.0 1.5e-10 41.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ20048.1 - 7.5e-06 26.6 0.0 1.5e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ20048.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAJ20048.1 - 4e-05 23.2 0.0 9.8e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.19 OAJ20048.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAJ20048.1 - 0.0029 17.7 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAJ20048.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 OAJ20048.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TMEM65 PF10507.9 OAJ20048.1 - 0.19 11.7 0.0 5.8 6.9 0.0 2.7 3 0 0 3 3 3 0 Transmembrane protein 65 Ribosomal_S4e PF00900.20 OAJ20050.1 - 1.7e-36 123.9 0.2 3.7e-36 122.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAJ20050.1 - 3.9e-24 84.0 0.8 8.8e-24 82.9 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAJ20050.1 - 9.1e-20 70.5 5.3 1.8e-19 69.5 5.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 OAJ20050.1 - 6.9e-05 22.7 1.3 0.0002 21.2 1.3 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 OAJ20050.1 - 0.00043 19.9 0.2 0.00092 18.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Sipho_tail PF05709.11 OAJ20050.1 - 0.13 11.6 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage tail protein Thiolase_N PF00108.23 OAJ20051.1 - 3.5e-15 56.1 1.9 3.2e-13 49.7 0.0 2.9 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ20051.1 - 7.4e-12 45.0 0.9 4.6e-11 42.4 0.2 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain Ketoacyl-synt_C PF02801.22 OAJ20051.1 - 0.0043 17.1 0.3 0.049 13.7 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 OAJ20051.1 - 0.015 14.9 4.5 1.2 8.6 1.6 2.5 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ20051.1 - 0.017 14.9 1.6 0.28 11.1 0.5 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III YadA_anchor PF03895.15 OAJ20051.1 - 7.2 6.8 9.4 1.1 9.4 0.4 3.1 3 0 0 3 3 3 0 YadA-like membrane anchor domain DUF1741 PF08427.10 OAJ20052.1 - 7.9e-05 22.4 0.3 0.41 10.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1741) MCM PF00493.23 OAJ20053.1 - 2.6e-101 337.4 0.0 3.8e-101 336.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ20053.1 - 2.8e-29 101.5 0.1 4.7e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ20053.1 - 1.4e-19 70.2 0.9 3.6e-19 69.0 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ20053.1 - 1.7e-14 54.2 0.0 4.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ20053.1 - 1.7e-07 31.3 0.0 2.1e-05 24.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ20053.1 - 7e-07 28.8 0.0 5e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 OAJ20053.1 - 0.0048 17.5 0.4 0.016 15.8 0.4 2.0 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 OAJ20053.1 - 0.023 14.6 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 OAJ20053.1 - 0.032 14.1 0.9 0.098 12.5 0.9 1.8 1 0 0 1 1 1 0 AAA lid domain adh_short PF00106.25 OAJ20054.1 - 4.8e-08 32.7 0.1 9.2e-08 31.8 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAJ20054.1 - 9.5e-05 22.4 0.1 0.00016 21.6 0.1 1.4 1 0 0 1 1 1 1 KR domain DAO PF01266.24 OAJ20054.1 - 0.011 15.4 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase TAF PF02969.17 OAJ20055.1 - 1.9e-23 82.4 0.1 4.3e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OAJ20055.1 - 1.6e-14 54.0 0.0 5.1e-14 52.4 0.0 1.8 1 1 1 2 2 2 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 OAJ20055.1 - 4.6e-05 23.8 0.6 0.00011 22.6 0.6 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAJ20055.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 OAJ20056.1 - 8e-15 54.4 0.0 3e-06 26.9 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ20056.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF3295 PF11702.8 OAJ20057.1 - 1.3e-11 44.6 1.9 1.3e-11 44.6 1.9 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF3295) Xpo1 PF08389.12 OAJ20058.1 - 6.6e-16 58.7 0.0 1.1e-13 51.5 0.0 3.1 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 OAJ20058.1 - 0.00062 20.1 0.6 0.0093 16.3 0.1 3.2 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 OAJ20058.1 - 0.019 15.2 0.2 1.1 9.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Pro_isomerase PF00160.21 OAJ20059.1 - 2.5e-47 161.1 0.3 3.2e-47 160.7 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EPL1 PF10513.9 OAJ20060.1 - 2.5e-18 67.0 0.1 2.5e-18 67.0 0.1 5.4 5 1 0 5 5 5 1 Enhancer of polycomb-like Phosphodiest PF01663.22 OAJ20082.1 - 3.4e-05 23.6 0.0 6.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DDOST_48kD PF03345.14 OAJ20083.1 - 3e-102 342.6 0.0 5.8e-102 341.6 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta adh_short_C2 PF13561.6 OAJ20084.1 - 5.2e-56 189.8 0.0 6.9e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ20084.1 - 2.4e-39 134.8 0.1 3e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ20084.1 - 1.6e-07 31.5 0.0 2.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 KR domain GTP_EFTU PF00009.27 OAJ20085.1 - 4.3e-57 192.8 0.6 7e-57 192.1 0.6 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ20085.1 - 6.5e-29 100.5 0.0 1.3e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ20085.1 - 2.2e-17 63.2 2.9 2.2e-17 63.2 2.9 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ20085.1 - 1.9e-05 24.7 0.1 3.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ20085.1 - 0.0022 17.9 0.2 0.007 16.3 0.1 1.7 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 OAJ20085.1 - 0.0051 16.4 1.0 0.0069 16.0 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAJ20085.1 - 0.034 13.9 0.9 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tim54 PF11711.8 OAJ20086.1 - 6.8e-40 137.0 0.0 1.3e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Zn_clus PF00172.18 OAJ20087.1 - 5.6e-08 32.8 10.4 1e-07 32.0 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ20087.1 - 0.0024 16.9 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SUIM_assoc PF16619.5 OAJ20087.1 - 0.015 15.4 1.0 0.015 15.4 1.0 6.8 6 1 1 7 7 7 0 Unstructured region C-term to UIM in Ataxin3 TPR_10 PF13374.6 OAJ20087.1 - 1.6 8.7 3.9 15 5.6 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apolipoprotein PF01442.18 OAJ20088.1 - 0.19 11.6 7.3 0.39 10.6 7.3 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain 4HBT PF03061.22 OAJ20089.1 - 0.0002 21.6 0.2 0.31 11.4 0.0 2.9 2 1 0 2 2 2 2 Thioesterase superfamily DUF1501 PF07394.12 OAJ20089.1 - 0.011 14.9 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Dimer_Tnp_hAT PF05699.14 OAJ20092.1 - 2.5e-09 36.8 0.0 4.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Hydantoinase_B PF02538.14 OAJ20093.1 - 4.3e-210 698.5 0.1 5.3e-210 698.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Pacs-1 PF10254.9 OAJ20094.1 - 0.045 12.7 1.1 0.062 12.3 1.1 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein COPI_C PF06957.11 OAJ20096.1 - 0.1 11.4 12.1 0.043 12.6 3.0 3.6 4 0 0 4 4 4 0 Coatomer (COPI) alpha subunit C-terminus Trypan_PARP PF05887.11 OAJ20097.1 - 0.0011 19.0 21.5 0.0011 19.0 21.5 2.7 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) Cellulase PF00150.18 OAJ20098.1 - 7.8e-16 58.3 0.1 7.8e-15 55.0 0.1 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PG_binding_3 PF09374.10 OAJ20098.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Mid1 PF12929.7 OAJ20100.1 - 7.6e-54 183.5 0.0 1.2e-53 182.9 0.0 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAJ20100.1 - 0.017 15.7 2.2 0.049 14.3 0.2 2.3 2 0 0 2 2 2 0 Fz domain LSM PF01423.22 OAJ20103.1 - 3e-22 78.1 0.1 3.7e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ20103.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Membr_traf_MHD PF10540.9 OAJ20104.1 - 2.3e-13 50.6 0.2 1.2e-06 28.7 0.5 2.6 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAJ20104.1 - 1.7e-07 31.4 0.0 4.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain CCDC24 PF15669.5 OAJ20104.1 - 0.081 12.8 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF810 PF05664.11 OAJ20104.1 - 0.18 10.3 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Pkinase PF00069.25 OAJ20105.1 - 1.4e-73 247.6 0.1 2.3e-73 246.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20105.1 - 3.8e-52 177.2 1.2 4.1e-52 177.0 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAJ20105.1 - 1.6e-22 79.6 0.0 3.5e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 OAJ20105.1 - 7.1e-11 42.6 0.8 1.3e-10 41.7 0.8 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 OAJ20105.1 - 1.5e-05 24.5 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ20105.1 - 5.9e-05 22.0 7.6 0.00028 19.8 7.6 1.9 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ20105.1 - 0.00072 18.6 0.3 0.0015 17.5 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 OAJ20105.1 - 0.0011 19.0 2.5 0.034 14.1 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family PH_11 PF15413.6 OAJ20105.1 - 0.14 12.6 6.9 0.2 12.1 1.2 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain BAF1_ABF1 PF04684.13 OAJ20105.1 - 0.15 11.1 4.6 0.2 10.7 4.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3915 PF13054.6 OAJ20105.1 - 1.1 9.3 7.9 2.2 8.3 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Glyco_hydro_32N PF00251.20 OAJ20106.1 - 1.5e-38 133.1 0.5 1.2e-26 94.0 0.1 3.5 2 2 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ20106.1 - 6.2e-22 78.3 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Ig_mannosidase PF17753.1 OAJ20107.1 - 1.7e-12 46.9 0.0 7.6e-12 44.8 0.0 2.2 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 OAJ20107.1 - 3.3e-10 40.6 0.2 7.2e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 OAJ20107.1 - 7.4e-09 36.1 1.0 3.2e-08 34.1 0.2 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain CTNNB1_binding PF08347.11 OAJ20108.1 - 0.0045 17.2 0.8 0.016 15.4 0.1 2.0 2 0 0 2 2 2 1 N-terminal CTNNB1 binding MMgT PF10270.9 OAJ20109.1 - 1.5e-12 47.7 0.0 2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Defensin_propep PF00879.18 OAJ20109.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Defensin propeptide NUP50 PF08911.11 OAJ20110.1 - 7.3e-06 26.6 1.3 7.3e-06 26.6 1.3 6.6 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) DUF4632 PF15451.6 OAJ20110.1 - 0.081 13.0 0.1 0.081 13.0 0.1 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4632) Cwf_Cwc_15 PF04889.12 OAJ20110.1 - 0.87 9.3 14.4 1.9 8.1 14.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4483 PF14825.6 OAJ20110.1 - 1.6 8.5 5.2 21 4.9 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4483) Sugar_tr PF00083.24 OAJ20111.1 - 7.6e-68 229.4 12.0 9.3e-68 229.1 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20111.1 - 2.7e-14 52.9 19.5 2.7e-14 52.9 19.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MnhB PF04039.13 OAJ20112.1 - 0.016 15.5 0.8 0.029 14.7 0.8 1.4 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter TraT PF05818.12 OAJ20112.1 - 7.7 6.1 6.6 15 5.2 6.6 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein FKBP_C PF00254.28 OAJ20126.1 - 9.5e-31 106.0 0.0 1.1e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase HAD PF12710.7 OAJ20127.1 - 0.00027 21.4 0.1 0.082 13.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 OAJ20128.1 - 1.8e-12 48.2 0.1 2.9e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adeno_E1B_55K_N PF04623.12 OAJ20128.1 - 0.11 13.2 4.0 0.29 11.9 4.0 1.7 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus AAA_2 PF07724.14 OAJ20129.1 - 2.7e-47 161.1 0.0 1.5e-43 148.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ20129.1 - 1.6e-32 111.5 7.2 3.9e-31 107.1 1.9 4.2 4 0 0 4 4 3 1 AAA lid domain ClpB_D2-small PF10431.9 OAJ20129.1 - 1.6e-23 82.6 0.2 6.3e-23 80.6 0.2 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAJ20129.1 - 1.5e-22 80.4 0.0 3.1e-13 50.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ20129.1 - 1.1e-12 48.1 0.0 8.3e-06 25.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ20129.1 - 4.5e-12 46.7 9.8 1.5e-07 31.9 0.3 4.9 4 1 0 4 4 4 2 AAA ATPase domain Clp_N PF02861.20 OAJ20129.1 - 2.2e-11 43.7 3.4 9.4e-06 25.7 0.6 3.9 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 OAJ20129.1 - 1.6e-09 38.1 1.5 0.0032 17.7 0.1 4.9 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OAJ20129.1 - 2e-07 30.9 0.1 0.047 13.4 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein TniB PF05621.11 OAJ20129.1 - 2.1e-06 27.3 0.1 0.0095 15.4 0.1 3.3 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OAJ20129.1 - 2.2e-06 27.3 0.0 0.075 12.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 OAJ20129.1 - 2.3e-06 27.4 0.0 0.0028 17.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 OAJ20129.1 - 9.2e-06 26.2 0.1 0.08 13.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 OAJ20129.1 - 1.6e-05 25.1 0.0 0.033 14.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 OAJ20129.1 - 2.5e-05 24.3 4.4 0.23 11.4 0.0 3.9 3 1 0 4 4 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 OAJ20129.1 - 9e-05 22.8 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 OAJ20129.1 - 0.00013 21.3 0.0 0.51 9.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAJ20129.1 - 0.00016 21.5 0.1 0.52 10.0 0.0 4.0 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 OAJ20129.1 - 0.00026 20.9 0.0 0.055 13.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 OAJ20129.1 - 0.00028 20.8 0.0 0.68 9.8 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase Roc PF08477.13 OAJ20129.1 - 0.00028 21.1 0.0 1.2 9.4 0.0 2.9 3 0 0 3 3 2 2 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 OAJ20129.1 - 0.0003 20.1 0.9 0.4 9.8 0.0 3.3 2 1 1 3 3 3 1 TIP49 P-loop domain TsaE PF02367.17 OAJ20129.1 - 0.00033 20.6 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 OAJ20129.1 - 0.00051 19.8 0.0 0.66 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 OAJ20129.1 - 0.00062 20.1 0.3 4.1 7.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 OAJ20129.1 - 0.00065 20.1 0.1 0.35 11.2 0.0 4.0 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OAJ20129.1 - 0.0008 18.8 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 OAJ20129.1 - 0.0031 17.4 0.0 2.1 8.2 0.0 2.9 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 OAJ20129.1 - 0.0039 16.5 0.0 0.92 8.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OAJ20129.1 - 0.0057 16.4 0.0 1.8 8.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 OAJ20129.1 - 0.0073 16.0 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 OAJ20129.1 - 0.0077 15.9 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_23 PF13476.6 OAJ20129.1 - 0.0083 16.6 12.9 0.091 13.3 0.0 4.1 2 2 0 2 2 1 1 AAA domain ABC_tran PF00005.27 OAJ20129.1 - 0.0084 16.6 0.5 1.9 9.0 0.0 3.3 4 0 0 4 4 2 1 ABC transporter AAA_14 PF13173.6 OAJ20129.1 - 0.0098 15.9 0.0 3.7 7.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 OAJ20129.1 - 0.012 15.5 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 OAJ20129.1 - 0.018 14.8 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 OAJ20129.1 - 0.048 13.5 0.0 18 5.2 0.0 3.7 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Cob_adeno_trans PF01923.18 OAJ20129.1 - 0.057 13.5 0.9 0.19 11.8 0.9 2.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_8 PF12780.7 OAJ20129.1 - 0.076 12.3 0.1 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 ResIII PF04851.15 OAJ20129.1 - 0.11 12.5 0.0 94 2.9 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ADIP PF11559.8 OAJ20129.1 - 0.23 11.5 6.3 0.87 9.7 6.3 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 OAJ20129.1 - 1.4 8.2 12.3 0.6 9.4 9.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CorA PF01544.18 OAJ20129.1 - 1.6 7.9 5.4 3.8 6.7 5.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PV-1 PF06637.11 OAJ20129.1 - 1.9 7.3 8.7 3.2 6.5 8.7 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4337 PF14235.6 OAJ20129.1 - 3.3 7.8 5.4 9.5 6.3 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.22 OAJ20129.1 - 3.9 7.8 16.4 16 5.8 10.8 4.0 3 1 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 OAJ20129.1 - 5.7 7.2 12.0 1.1 9.5 6.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SNARE_assoc PF09335.11 OAJ20130.1 - 7.5e-13 49.0 5.1 1.7e-12 47.9 5.1 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 OAJ20130.1 - 1.1 9.3 6.7 4.2 7.5 2.4 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III TFIIA PF03153.13 OAJ20130.1 - 1.3 8.9 26.1 0.41 10.6 5.1 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OAJ20130.1 - 1.4 7.0 10.0 2.1 6.4 10.0 1.2 1 0 0 1 1 1 0 Nop14-like family Aft1_HRA PF11786.8 OAJ20131.1 - 1e-24 86.6 14.1 1e-24 86.6 14.1 3.2 2 0 0 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.21 OAJ20131.1 - 3.8e-11 42.9 3.9 6.3e-11 42.2 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ20131.1 - 2.5e-06 27.5 6.6 8.1e-06 25.8 6.6 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Colipase PF01114.18 OAJ20132.1 - 0.046 13.4 0.6 0.046 13.4 0.6 9.3 9 1 1 10 10 10 0 Colipase, N-terminal domain TFB6 PF17110.5 OAJ20133.1 - 0.00067 19.5 3.9 0.1 12.3 0.0 3.6 3 1 0 3 3 3 2 Subunit 11 of the general transcription factor TFIIH TFIIF_alpha PF05793.12 OAJ20133.1 - 0.26 9.8 15.2 0.38 9.3 15.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.32 OAJ20134.1 - 3.1e-11 43.6 11.6 2e-06 28.4 2.2 5.8 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ20134.1 - 1.3e-08 35.0 0.1 0.023 15.0 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ20134.1 - 5.2e-05 23.2 0.0 0.009 15.9 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 OAJ20134.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 OAJ20134.1 - 0.038 12.5 0.0 1.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain TFIIIC_delta PF12657.7 OAJ20134.1 - 0.039 13.9 0.4 11 6.0 0.1 2.7 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term PQQ_3 PF13570.6 OAJ20134.1 - 0.041 14.4 0.8 0.51 10.9 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain Whi5 PF08528.11 OAJ20135.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like U3_assoc_6 PF08640.11 OAJ20136.1 - 8.7e-12 44.9 0.6 2.1e-10 40.5 0.5 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF1768 PF08719.11 OAJ20138.1 - 9.1e-26 91.0 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ20138.1 - 0.00025 20.9 0.0 0.00056 19.7 0.0 1.5 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 HEM4 PF02602.15 OAJ20139.1 - 1.8e-17 63.5 0.5 8.1e-09 35.2 0.1 4.5 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD Mob_synth_C PF06463.13 OAJ20140.1 - 3.6e-33 114.2 0.0 3.4e-32 111.1 0.0 2.1 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAJ20140.1 - 9.6e-30 104.2 0.0 1.5e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAJ20140.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAJ20140.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain MoaC PF01967.21 OAJ20141.1 - 2e-43 147.8 1.8 8.7e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 MoaC family Ras PF00071.22 OAJ20142.1 - 7.1e-65 217.5 0.0 8.3e-65 217.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ20142.1 - 6.1e-34 116.8 0.1 9.5e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ20142.1 - 2.7e-13 49.7 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ20142.1 - 6.1e-05 22.6 0.1 0.00015 21.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ20142.1 - 0.00023 20.6 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ20142.1 - 0.00029 20.9 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ20142.1 - 0.00042 20.3 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OAJ20142.1 - 0.031 13.7 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAJ20142.1 - 0.032 14.6 0.0 0.056 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAJ20142.1 - 0.049 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 OAJ20142.1 - 0.051 12.7 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain NACHT PF05729.12 OAJ20142.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 OAJ20142.1 - 0.068 12.7 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 OAJ20142.1 - 0.088 13.2 0.0 0.96 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAJ20142.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin SH3_1 PF00018.28 OAJ20143.1 - 4e-24 84.0 0.0 6e-11 41.8 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ20143.1 - 1.2e-13 50.7 0.0 7.9e-07 28.8 0.0 3.0 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 OAJ20143.1 - 2.1e-13 49.8 0.0 1.2e-08 34.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 OAJ20143.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 OAJ20143.1 - 0.0001 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 PB1 domain zf-CSL PF05207.13 OAJ20144.1 - 5.2e-22 77.3 0.8 8e-22 76.7 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 OAJ20144.1 - 0.00058 19.9 0.5 0.00098 19.2 0.5 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 OAJ20144.1 - 0.0064 16.4 1.0 0.011 15.7 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.6 OAJ20144.1 - 0.037 13.8 0.5 0.066 13.0 0.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_7 PF02591.15 OAJ20144.1 - 0.048 13.9 0.3 0.11 12.7 0.1 1.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain Sad1_UNC PF07738.13 OAJ20146.1 - 1.4e-19 70.5 0.0 3.7e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF2849 PF11011.8 OAJ20146.1 - 9.5 7.0 13.2 14 6.4 3.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Syja_N PF02383.18 OAJ20147.1 - 4.3e-87 292.4 0.0 5.4e-87 292.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain GCV_H PF01597.19 OAJ20148.1 - 2.7e-41 140.3 0.4 3.2e-41 140.0 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OAJ20148.1 - 0.0002 21.2 1.5 0.00044 20.0 0.4 2.1 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.6 OAJ20148.1 - 0.0014 18.5 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 OAJ20148.1 - 0.1 11.8 0.3 12 5.1 0.0 2.2 1 1 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion tRNA_m1G_MT PF01746.21 OAJ20149.1 - 4.9e-17 62.3 0.1 1.6e-13 50.8 0.1 3.2 2 1 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase CNDH2_C PF16858.5 OAJ20149.1 - 3.1 7.6 12.9 2.9 7.7 4.5 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Rtf2 PF04641.12 OAJ20150.1 - 4.1e-58 196.8 4.5 2.6e-57 194.2 0.1 2.8 1 1 1 2 2 2 1 Rtf2 RING-finger Gag_p12 PF01141.18 OAJ20150.1 - 0.067 13.5 0.1 0.067 13.5 0.1 2.9 3 0 0 3 3 3 0 Gag polyprotein, inner coat protein p12 zf-Nse PF11789.8 OAJ20150.1 - 0.081 12.8 0.1 1.1 9.1 0.0 2.4 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 OAJ20150.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Mcm10 PF09332.11 OAJ20150.1 - 0.59 9.5 10.4 0.8 9.1 10.4 1.2 1 0 0 1 1 1 0 Mcm10 replication factor DUF4407 PF14362.6 OAJ20150.1 - 1.2 8.4 13.1 2.2 7.6 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5327 PF17261.2 OAJ20150.1 - 6.8 7.5 8.3 22 5.9 4.2 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Hydrolase_4 PF12146.8 OAJ20152.1 - 1.6e-15 57.1 0.0 6.3e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ20152.1 - 2.1e-13 50.6 0.4 7.6e-08 32.3 0.3 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAJ20152.1 - 2.4e-07 29.7 0.0 0.0063 15.2 0.0 3.1 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAJ20152.1 - 1.7e-05 25.5 0.1 1.7e-05 25.5 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 OAJ20152.1 - 0.0036 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OAJ20152.1 - 0.0089 15.6 0.0 0.054 13.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 OAJ20152.1 - 0.0097 15.8 0.1 0.11 12.3 0.0 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OAJ20152.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ub-Mut7C PF14451.6 OAJ20152.1 - 0.13 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin Abhydrolase_5 PF12695.7 OAJ20152.1 - 0.2 11.4 0.0 0.99 9.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family zf-Tim10_DDP PF02953.15 OAJ20154.1 - 1e-19 69.9 5.3 1.3e-19 69.6 4.2 1.8 1 1 1 2 2 2 1 Tim10/DDP family zinc finger Solute_trans_a PF03619.16 OAJ20174.1 - 5e-75 252.4 13.3 6.2e-75 252.1 13.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Nramp PF01566.18 OAJ20174.1 - 0.037 13.0 0.2 0.069 12.1 0.2 1.3 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein PepSY_TM PF03929.16 OAJ20174.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.4 2 1 0 2 2 2 0 PepSY-associated TM region DNA_pol_phi PF04931.13 OAJ20174.1 - 0.19 9.8 0.1 0.27 9.3 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mon1 PF03164.14 OAJ20175.1 - 2.7e-77 260.5 0.0 2.3e-51 175.1 0.0 2.8 2 1 0 2 2 2 2 Trafficking protein Mon1 DUF3292 PF11696.8 OAJ20176.1 - 8.5e-202 672.0 0.0 1.3e-120 403.8 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) DDHD PF02862.17 OAJ20176.1 - 0.28 11.3 2.1 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 DDHD domain SRP72 PF08492.12 OAJ20176.1 - 1.4 9.4 10.4 1.2 9.6 2.4 2.6 2 0 0 2 2 2 0 SRP72 RNA-binding domain Formyl_trans_N PF00551.19 OAJ20177.1 - 2.8e-13 50.0 0.0 4.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 OAJ20177.1 - 8.4e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DSBA PF01323.20 OAJ20178.1 - 2.5e-27 95.9 0.0 3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Dopey_N PF04118.14 OAJ20179.1 - 4.3e-106 354.5 0.0 1.1e-105 353.1 0.0 1.7 2 0 0 2 2 2 1 Dopey, N-terminal DUF1658 PF07871.11 OAJ20179.1 - 0.073 13.0 0.4 0.24 11.4 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) UCR_hinge PF02320.16 OAJ20180.1 - 3.8e-11 43.0 7.0 6.8e-11 42.2 7.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.13 OAJ20180.1 - 0.37 10.7 5.8 0.46 10.3 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Mpp10 PF04006.12 OAJ20180.1 - 0.53 8.7 10.7 0.67 8.3 10.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Rhabdo_ncap PF00945.18 OAJ20180.1 - 0.72 8.7 1.8 0.88 8.4 1.8 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DNA_pol_phi PF04931.13 OAJ20180.1 - 2.6 6.0 6.7 3 5.8 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 OAJ20180.1 - 3.4 7.0 11.1 3.5 6.9 11.1 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.12 OAJ20180.1 - 3.6 6.9 12.0 4.6 6.6 12.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OAJ20180.1 - 5.6 5.1 6.2 5.5 5.1 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 OAJ20181.1 - 2.1e-21 75.5 0.0 1e-10 41.3 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gag_p12 PF01141.18 OAJ20181.1 - 0.092 13.1 9.5 0.027 14.8 4.1 3.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 RRM_7 PF16367.5 OAJ20181.1 - 0.13 12.4 0.0 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif DUF1752 PF08550.10 OAJ20182.1 - 5.2e-11 42.2 4.2 1.1e-10 41.1 4.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Mak16 PF04874.14 OAJ20182.1 - 0.038 14.6 0.7 0.083 13.5 0.7 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Ima1_N PF09779.9 OAJ20183.1 - 6e-26 91.9 1.4 8.8e-25 88.1 0.2 2.5 2 0 0 2 2 2 1 Ima1 N-terminal domain DKCLD PF08068.12 OAJ20184.1 - 3e-33 113.7 0.3 2.3e-32 110.8 0.5 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 OAJ20184.1 - 1.2e-23 84.1 0.2 1.8e-20 73.8 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ20184.1 - 2.8e-21 75.4 0.3 4.9e-21 74.6 0.3 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAJ20184.1 - 1.2e-19 70.0 0.7 2.4e-19 69.1 0.7 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAJ20184.1 - 0.0064 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_polI_A34 PF08208.11 OAJ20184.1 - 0.72 9.9 25.7 1.3 9.0 25.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N PF04086.13 OAJ20184.1 - 1.4 8.8 18.8 1.9 8.4 18.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal HLH PF00010.26 OAJ20185.1 - 0.015 15.2 0.2 0.027 14.4 0.2 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 OAJ20185.1 - 0.24 11.5 0.1 0.24 11.5 0.1 4.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Acetyltransf_6 PF13480.7 OAJ20185.1 - 1.9 8.6 4.0 3.7 7.7 4.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MTS PF05175.14 OAJ20186.1 - 4.2e-07 29.7 0.0 4.6e-05 23.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ20186.1 - 0.066 13.9 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ20186.1 - 0.13 13.3 0.0 0.33 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_4 PF12146.8 OAJ20189.1 - 1.7e-40 138.8 0.1 1.8e-20 73.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ20189.1 - 2.7e-11 43.6 0.2 4e-09 36.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ20189.1 - 3.7e-09 37.5 3.9 6.7e-09 36.7 3.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Asp2 PF16929.5 OAJ20189.1 - 0.0066 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Accessory Sec system GspB-transporter Peptidase_S15 PF02129.18 OAJ20189.1 - 0.027 14.1 0.2 1.6 8.2 0.1 2.6 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAJ20189.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase NIF PF03031.18 OAJ20190.1 - 3.7e-20 72.3 0.0 1.9e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase BRCT PF00533.26 OAJ20190.1 - 3.8e-06 27.2 0.0 6.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ20190.1 - 3.6e-05 23.6 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BUD22 PF09073.10 OAJ20190.1 - 0.0033 16.8 0.2 0.0033 16.8 0.2 4.1 2 2 1 3 3 3 1 BUD22 tRNA-synt_2 PF00152.20 OAJ20191.1 - 6.5e-77 258.7 0.2 8.5e-77 258.3 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ20191.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ20191.1 - 0.053 13.0 0.4 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SNF2_N PF00176.23 OAJ20192.1 - 8.4e-70 235.2 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 OAJ20192.1 - 2.3e-19 69.1 0.0 4.4e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 OAJ20192.1 - 1.1e-16 61.1 0.0 2.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20192.1 - 6.9e-07 29.4 0.0 4.2e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 OAJ20192.1 - 0.00038 20.3 11.8 0.00071 19.4 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ20192.1 - 0.0029 17.4 15.3 0.0056 16.5 15.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ20192.1 - 0.0076 16.6 14.8 0.014 15.7 14.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ20192.1 - 0.045 13.7 14.7 0.084 12.9 14.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.15 OAJ20192.1 - 0.19 11.3 0.1 0.98 9.0 0.1 2.0 1 1 0 1 1 1 0 DEAD_2 zf-C3HC4_2 PF13923.6 OAJ20192.1 - 0.93 9.4 14.8 2 8.3 14.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L22e PF01776.17 OAJ20193.1 - 5.7e-45 152.2 0.1 6.4e-45 152.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Acetyltransf_1 PF00583.25 OAJ20194.1 - 1.3e-06 28.6 0.0 0.0014 18.9 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ20194.1 - 3.6e-05 24.1 0.0 7.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ20194.1 - 0.00018 21.4 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ20194.1 - 0.014 15.5 0.0 0.065 13.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAJ20194.1 - 0.69 9.6 3.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PAP2 PF01569.21 OAJ20195.1 - 2.2e-11 43.7 4.1 3.3e-10 39.9 4.1 2.3 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OAJ20195.1 - 0.037 14.1 3.6 0.15 12.2 0.1 2.8 2 2 1 3 3 3 0 Divergent PAP2 family DUF2517 PF10725.9 OAJ20195.1 - 0.079 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) AMP-binding PF00501.28 OAJ20196.1 - 1.3e-70 238.1 0.0 1.8e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAJ20196.1 - 0.0063 16.8 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 OAJ20196.1 - 0.046 13.5 9.7 22 5.0 0.1 5.8 7 1 0 7 7 7 0 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ20196.1 - 0.34 10.7 1.4 4.7 7.1 0.1 3.4 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Ank_2 PF12796.7 OAJ20197.1 - 3.2e-06 27.6 0.0 5.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 OAJ20197.1 - 9.2e-06 25.9 19.0 1.5e-05 25.2 6.6 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_5 PF13857.6 OAJ20197.1 - 1e-05 25.7 0.0 2.2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH_4 PF18044.1 OAJ20197.1 - 3.5e-05 23.5 14.4 0.001 18.8 3.5 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_3 PF13606.6 OAJ20197.1 - 3.8e-05 23.7 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH PF00642.24 OAJ20197.1 - 0.00017 21.4 12.0 0.0072 16.2 2.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.30 OAJ20197.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 OAJ20197.1 - 0.003 18.1 0.0 0.0059 17.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Torus PF16131.5 OAJ20197.1 - 0.0055 17.4 6.8 0.01 16.6 0.0 3.0 3 0 0 3 3 2 1 Torus domain zf_CCCH_4 PF18345.1 OAJ20197.1 - 0.022 14.8 1.5 0.022 14.8 1.5 2.6 3 0 0 3 3 2 0 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ20197.1 - 0.11 12.7 0.9 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family RRP7 PF12923.7 OAJ20197.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain LTV PF04180.14 OAJ20198.1 - 0.0086 15.8 3.8 0.59 9.8 1.6 2.4 2 0 0 2 2 2 2 Low temperature viability protein Nup88 PF10168.9 OAJ20198.1 - 0.014 13.2 2.0 0.022 12.6 2.0 1.2 1 0 0 1 1 1 0 Nuclear pore component Spc7 PF08317.11 OAJ20198.1 - 0.022 13.6 3.4 0.048 12.5 3.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 OAJ20198.1 - 0.18 12.1 5.1 0.14 12.5 1.8 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4455 PF14643.6 OAJ20198.1 - 1.5 7.4 6.9 0.22 10.1 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) CcdA PF07362.12 OAJ20198.1 - 1.8 9.0 6.0 26 5.3 0.1 3.6 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA cNMP_binding PF00027.29 OAJ20213.1 - 1.4e-26 92.4 0.1 4.5e-14 52.3 0.0 5.6 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 OAJ20213.1 - 1e-17 65.0 4.7 4.7e-11 43.3 2.6 3.1 2 0 0 2 2 2 2 Patatin-like phospholipase SH3_16 PF18348.1 OAJ20213.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Ytp1 PF10355.9 OAJ20214.1 - 2.2e-96 322.3 3.5 3.5e-96 321.7 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ20214.1 - 2.1e-14 53.2 6.0 3e-14 52.7 0.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Cyclin_N PF00134.23 OAJ20215.1 - 0.011 15.4 0.1 0.011 15.4 0.1 2.7 4 0 0 4 4 4 0 Cyclin, N-terminal domain TFIIA PF03153.13 OAJ20215.1 - 1.6 8.7 10.2 5 7.0 10.2 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR2 PF06218.11 OAJ20216.1 - 5.3e-95 318.8 0.1 6.1e-43 147.2 0.5 5.2 3 2 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.13 OAJ20216.1 - 0.0025 16.7 1.8 0.65 8.7 0.0 2.6 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 RFX_DNA_binding PF02257.15 OAJ20217.1 - 1.6e-21 76.7 0.4 3.2e-21 75.7 0.4 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain CDC45 PF02724.14 OAJ20217.1 - 0.1 10.9 3.4 0.16 10.3 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ20217.1 - 0.4 8.8 7.4 0.63 8.2 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ20217.1 - 0.47 9.8 8.1 0.94 8.8 8.1 1.5 1 0 0 1 1 1 0 SDA1 YL1 PF05764.13 OAJ20217.1 - 1.6 8.8 7.4 3.6 7.6 7.4 1.5 1 0 0 1 1 1 0 YL1 nuclear protein FYDLN_acid PF09538.10 OAJ20217.1 - 2.3 9.0 14.4 0.15 12.8 8.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) BTB PF00651.31 OAJ20218.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain AlaDh_PNT_N PF05222.15 OAJ20219.1 - 1e-27 97.1 0.0 1.6e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain ThiC-associated PF13667.6 OAJ20219.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 ThiC-associated domain ABC_membrane PF00664.23 OAJ20220.1 - 1.1e-50 172.8 1.4 1.5e-50 172.4 1.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ20220.1 - 3.6e-31 108.5 0.0 1.5e-30 106.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAJ20220.1 - 0.00038 20.9 0.1 0.0018 18.7 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 OAJ20220.1 - 0.0022 17.5 0.0 0.062 12.7 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ20220.1 - 0.0047 16.8 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OAJ20220.1 - 0.013 15.8 0.0 0.068 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ20220.1 - 0.015 15.3 0.1 0.79 9.7 0.0 3.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 OAJ20220.1 - 0.027 14.3 0.1 7.9 6.2 0.0 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 OAJ20220.1 - 0.047 14.1 0.1 1.1 9.6 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 OAJ20220.1 - 0.051 12.4 0.0 0.098 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DsrD PF08679.11 OAJ20220.1 - 0.07 13.4 0.1 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Zeta_toxin PF06414.12 OAJ20220.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 OAJ20220.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ20220.1 - 0.087 12.9 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 OAJ20220.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_M28 PF04389.17 OAJ20221.1 - 4.3e-35 121.2 0.0 9.6e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 HMG_box PF00505.19 OAJ20222.1 - 7.5e-12 45.5 0.4 1.7e-11 44.3 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ20222.1 - 3.6e-09 37.1 0.2 8.8e-09 35.8 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain DSPc PF00782.20 OAJ20223.1 - 6.5e-16 58.4 0.3 6.6e-14 51.9 0.7 2.6 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain WD40 PF00400.32 OAJ20224.1 - 6.1e-08 33.2 10.9 0.012 16.5 0.5 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_12 PF13424.6 OAJ20225.1 - 0.0039 17.4 0.8 0.093 13.0 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ20225.1 - 0.005 16.9 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ20225.1 - 0.032 14.1 0.2 0.94 9.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ20225.1 - 0.089 12.9 0.0 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Myotub-related PF06602.14 OAJ20226.1 - 5.7e-140 466.2 0.0 9.7e-140 465.5 0.0 1.4 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain adh_short PF00106.25 OAJ20228.1 - 8e-17 61.3 0.6 9.8e-16 57.8 0.7 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ20228.1 - 4.9e-08 32.8 1.1 0.0011 18.5 0.1 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ20228.1 - 6.1e-06 26.3 2.6 8.2e-05 22.6 0.3 2.2 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 OAJ20228.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNA_polI_A34 PF08208.11 OAJ20229.1 - 4.6e-14 53.0 15.7 6.3e-14 52.6 15.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 OAJ20229.1 - 1.8 8.3 8.1 2.5 7.9 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RabGAP-TBC PF00566.18 OAJ20230.1 - 9e-44 149.7 0.2 1.2e-43 149.3 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 OAJ20231.1 - 1.6e-06 28.0 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 OAJ20231.1 - 0.0017 18.4 1.0 0.0028 17.7 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 OAJ20231.1 - 0.004 17.3 2.1 0.01 16.0 2.1 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 HAP1_N PF04849.13 OAJ20231.1 - 0.011 14.9 2.0 0.016 14.4 2.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region SOGA PF11365.8 OAJ20231.1 - 0.016 16.3 0.7 0.049 14.8 0.4 1.9 1 1 1 2 2 2 0 Protein SOGA DUF3450 PF11932.8 OAJ20231.1 - 0.021 14.1 0.5 0.03 13.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc29 PF17082.5 OAJ20231.1 - 0.035 13.9 0.1 0.048 13.5 0.1 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 APG6_N PF17675.1 OAJ20231.1 - 0.042 14.4 3.5 0.07 13.7 3.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region VGPC1_C PF16799.5 OAJ20231.1 - 0.1 12.6 0.8 0.2 11.6 0.1 1.8 1 1 1 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DivIC PF04977.15 OAJ20231.1 - 1 9.1 5.5 8.4 6.3 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator DUF3759 PF12585.8 OAJ20232.1 - 2.5e-40 136.4 9.2 2.8e-40 136.3 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) zf-RRN7 PF11781.8 OAJ20233.1 - 0.014 15.1 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 OAJ20233.1 - 0.028 14.7 0.1 0.071 13.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase FAM72 PF14976.6 OAJ20234.1 - 1.4e-20 73.9 0.6 3e-20 72.8 0.6 1.5 1 0 0 1 1 1 1 FAM72 protein Hom_end_hint PF05203.16 OAJ20234.1 - 2.4 8.0 7.7 3.8 7.4 7.7 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint XRN_M PF17846.1 OAJ20234.1 - 7.3 5.4 8.2 11 4.9 8.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain RRM_1 PF00076.22 OAJ20235.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ20235.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif DUF4614 PF15391.6 OAJ20235.1 - 3.2 7.7 17.6 4.2 7.3 8.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SDA1 PF05285.12 OAJ20235.1 - 5.4 6.3 23.3 12 5.2 23.3 1.6 1 0 0 1 1 1 0 SDA1 Sec63 PF02889.16 OAJ20236.1 - 2.7e-67 226.6 0.0 5.7e-67 225.6 0.0 1.5 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 OAJ20236.1 - 4.8e-40 137.2 0.5 1.2e-25 90.3 0.0 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 OAJ20236.1 - 9.2e-14 51.8 0.0 6e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ20236.1 - 2.5e-06 27.8 0.0 0.003 17.9 0.0 4.4 3 2 0 3 3 3 1 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 OAJ20236.1 - 0.0011 19.2 0.2 0.0067 16.6 0.0 2.4 2 1 1 3 3 3 1 N-terminal helicase PWI domain AAA_22 PF13401.6 OAJ20236.1 - 0.0013 19.0 0.2 0.081 13.2 0.2 3.4 3 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 OAJ20236.1 - 0.011 14.8 0.1 0.81 8.7 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ20236.1 - 0.017 15.5 0.3 5.2 7.4 0.0 3.3 2 0 0 2 2 2 0 AAA ATPase domain UCH PF00443.29 OAJ20237.1 - 5.9e-42 143.9 0.0 2.1e-41 142.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ20237.1 - 7.5e-20 71.7 0.0 2.7e-11 43.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ20237.1 - 6e-07 29.7 3.4 6e-07 29.7 3.4 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.6 OAJ20237.1 - 1.2 9.5 12.8 1.5 9.2 7.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ20237.1 - 1.6 7.9 16.2 6 6.1 6.6 3.5 4 0 0 4 4 4 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ20237.1 - 2.4 7.8 7.1 0.71 9.6 2.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M43 PF05572.13 OAJ20238.1 - 2.4e-20 73.0 0.5 4e-20 72.3 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ20238.1 - 3.7e-07 30.7 0.1 2.5e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ20238.1 - 6.8e-05 23.1 4.0 0.00011 22.4 4.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAJ20238.1 - 0.0065 16.3 0.0 0.0082 16.0 0.0 1.3 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 OAJ20238.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Transglut_i_TM PF14400.6 OAJ20238.1 - 0.1 12.7 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices GTP_EFTU PF00009.27 OAJ20239.1 - 5.4e-55 186.0 0.0 9.2e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAJ20239.1 - 2.9e-14 52.9 0.0 6.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ20239.1 - 2.4e-08 33.9 0.0 5.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ20239.1 - 0.00085 19.7 0.0 0.0037 17.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAJ20239.1 - 0.017 14.9 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAJ20239.1 - 0.024 14.7 0.0 0.069 13.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase CPSase_L_D2 PF02786.17 OAJ20256.1 - 1.1e-105 351.8 0.0 3.3e-82 275.1 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAJ20256.1 - 1.7e-40 138.2 0.1 4.9e-40 136.7 0.1 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAJ20256.1 - 6.5e-16 58.4 0.0 4.8e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAJ20256.1 - 7.5e-13 48.5 0.1 1.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 OAJ20256.1 - 1.8e-10 40.6 0.0 0.00029 20.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAJ20256.1 - 2.8e-06 27.5 0.0 0.00068 19.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 OAJ20256.1 - 7.9e-06 25.5 0.3 0.017 14.6 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 OAJ20256.1 - 0.00059 19.5 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.22 OAJ20256.1 - 0.027 14.6 0.0 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain GARS_A PF01071.19 OAJ20256.1 - 0.03 14.1 0.1 6.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_M17_N PF02789.17 OAJ20256.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain ATP-grasp_2 PF08442.10 OAJ20256.1 - 0.15 11.6 0.0 7.3 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain MT-A70 PF05063.14 OAJ20257.1 - 4.6e-08 33.2 0.1 0.00019 21.4 0.3 3.5 3 1 0 3 3 3 2 MT-A70 DUF2205 PF10224.9 OAJ20258.1 - 4.9e-12 45.7 0.0 6e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 OAJ20258.1 - 0.00063 20.3 0.1 0.00078 20.1 0.1 1.1 1 0 0 1 1 1 1 Initiation control protein YabA TACC_C PF05010.14 OAJ20258.1 - 0.015 15.1 0.2 0.018 14.9 0.2 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal V-ATPase_G PF03179.15 OAJ20259.1 - 1.8e-33 115.2 17.1 2.1e-33 115.0 17.1 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit TFA2_Winged_2 PF18121.1 OAJ20259.1 - 0.11 12.2 1.0 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 ATP-synt_B PF00430.18 OAJ20259.1 - 0.37 10.9 20.1 3.3 7.8 20.1 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Halogen_Hydrol PF10112.9 OAJ20259.1 - 0.59 10.1 7.3 1.1 9.3 7.1 1.6 1 1 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3552 PF12072.8 OAJ20259.1 - 1.4 8.3 19.7 2.7 7.4 19.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) OmpH PF03938.14 OAJ20259.1 - 1.5 9.2 18.1 2 8.7 18.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZYG-11_interact PF05884.12 OAJ20259.1 - 1.6 8.1 4.0 1.6 8.1 4.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DDHD PF02862.17 OAJ20259.1 - 2.5 8.2 7.5 2.8 8.1 7.5 1.0 1 0 0 1 1 1 0 DDHD domain TMPIT PF07851.13 OAJ20259.1 - 2.5 7.2 8.0 2.8 7.1 8.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 OAJ20259.1 - 3.2 8.0 14.5 5.5 7.3 12.8 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lectin_N PF03954.14 OAJ20259.1 - 3.2 7.5 6.7 2.3 8.0 4.8 1.6 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4407 PF14362.6 OAJ20259.1 - 7.7 5.8 15.3 9.6 5.5 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Proteasome PF00227.26 OAJ20260.1 - 3.5e-51 173.4 0.0 4.5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ20260.1 - 3.2e-11 42.7 0.1 5.5e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SNF5 PF04855.12 OAJ20262.1 - 2.2e-60 204.4 2.0 2.2e-60 204.4 2.0 2.7 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAJ20262.1 - 0.011 15.3 0.9 0.027 14.1 0.9 1.7 1 0 0 1 1 1 0 GATA zinc finger Mito_carr PF00153.27 OAJ20263.1 - 4.4e-62 206.0 4.9 1.5e-20 72.9 0.3 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF681 PF05080.12 OAJ20263.1 - 0.12 13.1 0.8 0.32 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF681) Methyltransf_23 PF13489.6 OAJ20264.1 - 6.3e-16 58.7 0.0 7.6e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ20264.1 - 2.5e-09 37.7 0.0 4.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ20264.1 - 4.1e-09 37.1 0.0 6.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ20264.1 - 2.4e-05 24.2 0.0 5.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ20264.1 - 8.7e-05 23.2 0.0 0.00016 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAJ20264.1 - 0.00037 19.5 0.0 0.00048 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Aerolysin PF01117.20 OAJ20264.1 - 0.049 12.8 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Aerolysin toxin PCMT PF01135.19 OAJ20264.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Chitin_synth_1 PF01644.17 OAJ20266.1 - 2e-35 122.2 0.0 1.8e-31 109.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.15 OAJ20266.1 - 3.6e-10 39.1 0.0 4.8e-06 25.5 0.0 2.4 1 1 1 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ20266.1 - 9e-09 35.2 0.0 9e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase N-terminal RNA_pol_I_A49 PF06870.12 OAJ20267.1 - 2.5e-82 276.8 0.1 6.2e-82 275.5 0.0 1.6 2 0 0 2 2 2 1 A49-like RNA polymerase I associated factor DUF937 PF06078.11 OAJ20267.1 - 0.031 14.9 0.0 0.099 13.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) PPR_2 PF13041.6 OAJ20268.1 - 2e-26 91.9 0.0 2.9e-07 30.6 0.0 8.9 9 0 0 9 9 9 4 PPR repeat family PPR PF01535.20 OAJ20268.1 - 1.9e-18 65.3 5.9 0.008 16.4 0.0 9.5 10 0 0 10 10 10 4 PPR repeat PPR_1 PF12854.7 OAJ20268.1 - 2.6e-11 43.0 0.1 0.27 11.0 0.0 7.7 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 OAJ20268.1 - 4.8e-10 39.4 0.0 0.12 12.5 0.0 6.0 5 1 1 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 OAJ20268.1 - 0.001 18.5 0.6 0.028 13.8 0.0 3.4 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP MNE1 PF13762.6 OAJ20268.1 - 0.025 14.5 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component TPR_19 PF14559.6 OAJ20268.1 - 0.052 14.0 3.5 0.98 10.0 0.0 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ20268.1 - 3.5 8.7 19.0 0.48 11.4 0.1 7.8 10 0 0 10 10 10 0 Tetratricopeptide repeat DLIC PF05783.11 OAJ20269.1 - 1.3e-45 156.1 7.0 7.1e-27 94.4 0.0 6.9 6 1 1 7 7 7 5 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 OAJ20269.1 - 7.9e-05 23.1 0.5 0.00081 19.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 OAJ20269.1 - 0.00017 20.7 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_28 PF13521.6 OAJ20269.1 - 0.014 15.6 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAJ20269.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 OAJ20269.1 - 0.092 13.2 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 OAJ20269.1 - 0.13 11.8 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cyanate_lyase PF02560.14 OAJ20270.1 - 1e-34 118.2 0.0 1.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 OAJ20270.1 - 9.2e-05 22.7 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OAJ20270.1 - 0.029 14.4 0.1 0.11 12.5 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix HTH_26 PF13443.6 OAJ20270.1 - 0.14 12.6 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain KorB PF08535.10 OAJ20270.1 - 0.19 11.8 0.0 0.42 10.7 0.1 1.6 2 0 0 2 2 2 0 KorB domain DnaJ PF00226.31 OAJ20271.1 - 5.2e-20 71.3 0.2 6.1e-19 67.9 0.2 2.7 1 1 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 OAJ20272.1 - 5.7e-127 424.3 19.5 6.5e-127 424.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20272.1 - 1.8e-20 73.2 36.3 7.3e-18 64.6 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1 PF00133.22 OAJ20273.1 - 1.3e-215 717.3 0.0 2.7e-214 712.9 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ20273.1 - 1.1e-37 129.4 0.4 2.2e-37 128.3 0.4 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ20273.1 - 3.1e-17 62.4 0.8 1e-08 34.3 0.2 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ20273.1 - 7.2e-10 38.7 0.6 4.4e-06 26.3 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ20273.1 - 0.0002 20.8 0.0 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 OAJ20273.1 - 0.00044 20.5 2.9 0.00044 20.5 2.9 2.8 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.19 OAJ20273.1 - 0.15 10.9 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (R) Phage_holin_6_1 PF09682.10 OAJ20273.1 - 7.3 7.1 6.7 23 5.5 6.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Abhydrolase_6 PF12697.7 OAJ20274.1 - 1.5e-12 48.6 0.0 2.4e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ20274.1 - 1.4e-07 31.4 0.1 4e-07 29.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ20274.1 - 1.9e-07 30.6 0.0 6.6e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 WD40 PF00400.32 OAJ20275.1 - 9.9e-15 54.7 0.8 4.3e-07 30.5 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ20275.1 - 0.00021 21.5 0.0 0.56 10.5 0.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAJ20275.1 - 0.059 13.9 0.0 0.4 11.2 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain GTP_EFTU PF00009.27 OAJ20276.1 - 8.4e-54 182.1 0.0 1.3e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ20276.1 - 1.3e-40 138.2 0.0 3e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ20276.1 - 3.8e-14 52.8 2.7 4.3e-14 52.7 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ20276.1 - 0.00039 20.5 0.1 0.0095 16.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.16 OAJ20276.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 OAJ20276.1 - 0.071 13.0 0.8 0.27 11.2 0.8 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 AAA_29 PF13555.6 OAJ20276.1 - 0.075 12.8 0.0 14 5.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain MULE PF10551.9 OAJ20277.1 - 5.5e-28 97.2 0.1 1.1e-27 96.3 0.1 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ20277.1 - 0.00021 20.3 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family zf-CCHC_6 PF15288.6 OAJ20277.1 - 0.0025 17.6 0.6 0.0058 16.4 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle FAR1 PF03101.15 OAJ20277.1 - 0.0091 16.7 1.4 0.0091 16.7 1.4 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain DNA_pol_B PF00136.21 OAJ20278.1 - 2.5e-150 501.2 0.4 3.8e-150 500.6 0.2 1.4 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ20278.1 - 6.7e-77 258.9 0.0 4.8e-76 256.1 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ20278.1 - 2.9e-17 62.9 7.8 6.5e-17 61.8 7.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAJ20278.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 OAJ20278.1 - 0.013 14.4 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 OAJ20278.1 - 0.045 13.7 0.1 0.2 11.6 0.1 2.2 1 1 0 1 1 1 0 RNase_H superfamily Amino_oxidase PF01593.24 OAJ20279.1 - 5.5e-62 210.5 0.4 6.3e-62 210.3 0.4 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ20279.1 - 4.7e-11 42.8 0.6 1.1e-10 41.6 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ20279.1 - 1.6e-06 27.1 2.0 0.0038 16.0 0.8 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAJ20279.1 - 4.7e-06 26.4 3.1 1.6e-05 24.7 3.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ20279.1 - 2.1e-05 23.8 1.6 3.9e-05 22.9 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAJ20279.1 - 0.0002 21.8 0.2 0.0023 18.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ20279.1 - 0.00081 18.7 0.5 0.0041 16.4 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ20279.1 - 0.0014 17.9 0.8 0.0022 17.3 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ20279.1 - 0.0022 17.3 0.3 0.18 11.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ20279.1 - 0.005 16.8 2.3 1.5 8.8 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAJ20279.1 - 0.005 16.2 0.7 0.008 15.6 0.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ20279.1 - 0.0066 15.5 0.3 2.4 7.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 OAJ20279.1 - 0.032 13.5 0.5 0.059 12.6 0.5 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAJ20279.1 - 0.29 10.2 1.0 1.1 8.2 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A E3_binding PF02817.17 OAJ20280.1 - 3.9e-07 30.3 1.2 4.5e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 e3 binding domain FH2 PF02181.23 OAJ20281.1 - 3.3e-84 283.1 0.0 4.5e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain HAD_2 PF13419.6 OAJ20282.1 - 2e-16 60.6 0.0 3.2e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ20282.1 - 6.4e-10 39.7 0.0 1e-08 35.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ20282.1 - 0.00068 20.1 0.0 0.0018 18.7 0.0 1.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAJ20282.1 - 0.13 12.4 0.0 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase OppC_N PF12911.7 OAJ20284.1 - 0.048 13.6 0.2 0.09 12.8 0.2 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF3328 PF11807.8 OAJ20284.1 - 1.1 8.9 4.7 6.7 6.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Peptidase_C65 PF10275.9 OAJ20286.1 - 1.7e-61 207.8 0.0 2.3e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 OAJ20286.1 - 0.0028 18.2 0.0 0.046 14.2 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Rdx PF10262.9 OAJ20302.1 - 1.4e-22 79.7 0.0 4.8e-22 77.9 0.0 1.9 1 1 0 1 1 1 1 Rdx family FF PF01846.19 OAJ20303.1 - 3.3e-23 81.6 2.7 6.9e-10 38.9 0.0 5.1 5 1 0 5 5 5 2 FF domain WW PF00397.26 OAJ20303.1 - 1.6e-13 50.5 11.1 1.8e-06 28.0 1.8 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 OAJ20303.1 - 0.014 16.0 0.3 0.014 16.0 0.3 3.0 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Vezatin PF12632.7 OAJ20304.1 - 7.6e-11 41.9 0.0 3.3e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes AAA PF00004.29 OAJ20305.1 - 1.2e-48 164.8 0.0 3.3e-43 147.3 0.0 3.9 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAJ20305.1 - 3.2e-20 72.3 0.0 7.7e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAJ20305.1 - 3.8e-15 55.4 0.5 3.9e-08 33.0 0.0 2.8 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 OAJ20305.1 - 7.7e-09 36.2 9.1 0.0011 19.4 1.8 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 OAJ20305.1 - 2e-06 28.1 0.1 0.57 10.5 0.1 4.5 4 1 1 5 5 5 2 AAA domain AAA_18 PF13238.6 OAJ20305.1 - 9.5e-06 26.2 0.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAJ20305.1 - 2.5e-05 24.0 2.1 1.1 8.8 0.0 4.4 3 1 0 4 4 4 1 AAA domain AAA_33 PF13671.6 OAJ20305.1 - 4.7e-05 23.6 0.0 0.049 13.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 OAJ20305.1 - 0.0001 22.3 0.4 0.6 10.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ20305.1 - 0.00021 21.1 0.0 0.0035 17.1 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 OAJ20305.1 - 0.00031 20.7 0.0 0.53 10.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAJ20305.1 - 0.00085 19.3 3.3 3.1 7.7 0.1 4.5 5 0 0 5 5 4 1 NACHT domain TIP49 PF06068.13 OAJ20305.1 - 0.0011 18.2 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OAJ20305.1 - 0.0013 18.1 0.2 0.96 8.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAJ20305.1 - 0.0017 18.8 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 OAJ20305.1 - 0.0025 18.1 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 OAJ20305.1 - 0.0062 17.0 0.2 0.49 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 OAJ20305.1 - 0.0063 16.3 0.2 2.3 7.9 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAJ20305.1 - 0.0096 16.1 0.0 0.068 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 OAJ20305.1 - 0.0097 15.2 0.9 4.2 6.6 0.4 2.4 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 OAJ20305.1 - 0.012 15.4 0.0 0.064 13.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OAJ20305.1 - 0.012 14.9 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 OAJ20305.1 - 0.018 15.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 OAJ20305.1 - 0.02 14.8 0.2 0.9 9.4 0.1 2.9 2 1 1 3 3 3 0 Adenylylsulphate kinase AAA_19 PF13245.6 OAJ20305.1 - 0.072 13.4 0.0 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ20305.1 - 0.073 12.8 0.3 0.57 10.0 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAJ20305.1 - 0.083 12.6 0.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 OAJ20305.1 - 0.09 12.1 0.2 12 5.1 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 OAJ20305.1 - 0.11 12.0 0.0 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ20305.1 - 0.12 12.1 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAJ20305.1 - 0.14 12.2 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 OAJ20305.1 - 0.17 12.0 0.2 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.22 OAJ20305.1 - 0.25 10.5 0.1 4.2 6.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin2 PF13189.6 OAJ20305.1 - 0.5 10.5 1.5 1.2 9.3 0.0 2.3 3 0 0 3 3 2 0 Cytidylate kinase-like family Cwf_Cwc_15 PF04889.12 OAJ20305.1 - 1.6 8.4 14.3 0.29 10.8 2.9 3.0 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein MT-A70 PF05063.14 OAJ20307.1 - 1.9e-36 125.6 0.4 7.1e-25 87.9 0.3 3.8 2 1 0 2 2 2 2 MT-A70 Sugar_tr PF00083.24 OAJ20308.1 - 9.7e-106 354.3 14.7 1.2e-105 354.0 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20308.1 - 4.8e-27 94.8 24.5 4.8e-27 94.8 24.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 OAJ20308.1 - 0.14 10.5 3.3 0.11 10.8 0.4 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 OAJ20308.1 - 7.6 6.9 6.4 0.93 9.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) RRP36 PF06102.12 OAJ20309.1 - 3e-34 118.4 12.9 3e-34 118.4 12.9 3.2 3 1 0 3 3 3 2 rRNA biogenesis protein RRP36 FlxA PF14282.6 OAJ20309.1 - 0.022 14.8 1.0 0.022 14.8 1.0 3.0 2 1 0 2 2 2 0 FlxA-like protein Med3 PF11593.8 OAJ20311.1 - 0.064 12.4 4.1 0.12 11.5 4.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RR_TM4-6 PF06459.12 OAJ20311.1 - 6.8 6.4 8.2 35 4.1 4.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4187 PF13821.6 OAJ20312.1 - 6.4e-17 61.1 5.1 1.5e-16 59.9 5.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3008 PF11450.8 OAJ20312.1 - 0.018 15.2 4.2 0.051 13.7 4.2 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) G-patch PF01585.23 OAJ20312.1 - 0.022 14.6 0.1 0.055 13.4 0.1 1.6 1 0 0 1 1 1 0 G-patch domain Got1 PF04178.12 OAJ20313.1 - 1.8e-28 99.2 19.0 2.4e-28 98.8 19.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family OAD_gamma PF04277.13 OAJ20313.1 - 5.8 7.6 8.3 2.3 8.9 0.3 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Hydrolase_4 PF12146.8 OAJ20314.1 - 1.8e-26 92.9 0.1 3.8e-26 91.8 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ20314.1 - 1.8e-08 34.3 1.2 3.3e-08 33.5 1.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ20314.1 - 3.8e-08 34.2 0.2 6.4e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 OAJ20314.1 - 0.011 15.3 0.0 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.20 OAJ20314.1 - 0.19 11.4 0.1 0.53 9.9 0.1 1.7 2 0 0 2 2 2 0 Putative esterase NUC173 PF08161.12 OAJ20316.1 - 2.5e-47 161.2 0.4 4.2e-45 153.9 0.0 3.3 3 0 0 3 3 3 1 NUC173 domain MMS19_C PF12460.8 OAJ20316.1 - 4.6e-05 22.7 19.4 0.0017 17.6 4.0 3.3 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal DUF4692 PF15763.5 OAJ20316.1 - 2.3 8.7 4.8 2.4 8.6 1.3 2.5 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Bax1-I PF01027.20 OAJ20316.1 - 3.8 7.3 5.3 9.8 5.9 5.3 1.6 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 CDC73_C PF05179.14 OAJ20317.1 - 5.3e-46 156.2 0.0 1.5e-45 154.7 0.0 1.8 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 OAJ20317.1 - 1.5e-05 24.5 0.0 2.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal F-box-like PF12937.7 OAJ20319.1 - 8.9e-05 22.3 0.1 0.00026 20.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAJ20319.1 - 0.00038 20.3 1.2 2.3 8.5 0.0 4.8 4 0 0 4 4 4 2 Leucine Rich repeat ORC_WH_C PF18137.1 OAJ20320.1 - 4.3e-25 88.4 0.1 4.3e-25 88.4 0.1 4.1 2 2 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 OAJ20320.1 - 1.2e-15 57.4 9.1 8.6e-13 48.1 0.2 4.7 4 1 1 5 5 5 3 Origin recognition complex (ORC) subunit 3 N-terminus Aldo_ket_red PF00248.21 OAJ20321.1 - 2.5e-78 263.3 0.0 2.8e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NDC10_II PF16787.5 OAJ20322.1 - 8.3e-39 133.5 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ20322.1 - 0.087 13.2 0.3 0.24 11.8 0.3 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Abhydrolase_3 PF07859.13 OAJ20323.1 - 7.6e-39 133.8 0.2 2.5e-31 109.2 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ20323.1 - 1.2e-09 37.6 0.0 3.5e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase Transketolase_C PF02780.20 OAJ20323.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain COesterase PF00135.28 OAJ20323.1 - 0.0072 15.2 0.1 0.031 13.1 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Ribonuc_red_sm PF00268.21 OAJ20324.1 - 3.2e-120 400.8 0.9 3.9e-120 400.5 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DPBB_1 PF03330.18 OAJ20325.1 - 0.00043 20.5 0.1 0.0014 18.9 0.0 1.9 2 0 0 2 2 2 1 Lytic transglycolase PRCC PF10253.9 OAJ20325.1 - 0.2 12.4 11.8 0.35 11.6 11.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SH3_9 PF14604.6 OAJ20326.1 - 7.6e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ20326.1 - 9.6e-05 21.9 0.1 0.0049 16.5 0.1 2.4 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ20326.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain G_path_suppress PF15991.5 OAJ20347.1 - 1.4 9.0 4.4 0.38 10.8 1.4 1.5 2 0 0 2 2 2 0 G-protein pathway suppressor RVT_1 PF00078.27 OAJ20348.1 - 2.5e-18 66.4 0.0 3.9e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ20348.1 - 5.7e-14 52.0 0.5 1.2e-13 51.0 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ20348.1 - 5.2e-06 26.7 0.1 1e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3585 PF12130.8 OAJ20348.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain rve PF00665.26 OAJ20349.1 - 1.5e-11 44.5 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3699 PF12480.8 OAJ20349.1 - 0.038 14.2 0.2 10 6.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3699) TFIIA PF03153.13 OAJ20351.1 - 4.1 7.3 5.8 5.2 7.0 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hist_deacetyl PF00850.19 OAJ20352.1 - 2.6e-81 273.5 0.1 4e-81 272.9 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Phage_integrase PF00589.22 OAJ20353.1 - 3.7e-06 26.8 0.0 5.8e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phosphoesterase PF04185.14 OAJ20354.1 - 5.5e-25 88.3 2.8 2e-24 86.4 2.8 1.8 1 1 0 1 1 1 1 Phosphoesterase family DDHD PF02862.17 OAJ20355.1 - 0.0088 16.2 0.2 3.6 7.7 0.0 2.3 2 0 0 2 2 2 2 DDHD domain CENP-B_dimeris PF09026.10 OAJ20356.1 - 1.6 9.1 10.7 5.1 7.6 10.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Hamartin PF04388.12 OAJ20356.1 - 6.4 5.3 7.4 8.8 4.9 7.4 1.2 1 0 0 1 1 1 0 Hamartin protein Cu-oxidase_3 PF07732.15 OAJ20357.1 - 3.4e-38 130.3 9.1 6.9e-37 126.1 3.0 3.9 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ20357.1 - 1.4e-33 115.5 10.0 1.3e-31 109.2 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ20357.1 - 1.6e-29 103.1 0.2 8.4e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase N_BRCA1_IG PF16158.5 OAJ20357.1 - 0.0012 19.5 0.0 0.0052 17.5 0.1 2.0 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene FlgD_ig PF13860.6 OAJ20357.1 - 0.069 13.0 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 FlgD Ig-like domain ETRAMP PF09716.10 OAJ20357.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 OAJ20358.1 - 1.2e-07 31.4 0.0 3.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20358.1 - 0.00064 19.1 0.0 0.051 12.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ20362.1 - 1.4e-06 27.8 0.0 9.8e-06 25.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20362.1 - 0.00048 19.5 0.0 0.17 11.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Vac14_Fig4_bd PF11916.8 OAJ20363.1 - 2.6e-75 252.0 6.4 2.6e-75 252.0 6.4 2.2 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAJ20363.1 - 1.4e-45 153.8 0.0 1.9e-40 137.4 0.0 4.1 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAJ20363.1 - 4.1e-15 54.6 1.1 0.00072 19.6 0.0 7.5 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 OAJ20363.1 - 1.5e-07 31.6 1.1 0.0033 17.5 0.4 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAJ20363.1 - 2e-06 28.2 6.2 0.072 13.6 0.0 6.9 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAJ20363.1 - 1.7e-05 25.1 11.7 2.3 8.7 0.1 6.3 5 1 1 6 6 6 2 HEAT repeats ParcG PF10274.9 OAJ20363.1 - 0.0001 22.5 0.5 0.092 12.9 0.1 3.1 4 0 0 4 4 4 2 Parkin co-regulated protein CLASP_N PF12348.8 OAJ20363.1 - 0.0012 18.5 0.5 13 5.3 0.0 4.2 3 1 1 4 4 4 2 CLASP N terminal DUF3385 PF11865.8 OAJ20363.1 - 0.016 15.1 0.1 1.2 9.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Dopey_N PF04118.14 OAJ20363.1 - 0.031 13.4 0.1 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Dopey, N-terminal Tti2 PF10521.9 OAJ20363.1 - 0.031 13.8 1.2 15 5.1 0.0 3.9 4 1 1 5 5 5 0 Tti2 family Arm PF00514.23 OAJ20363.1 - 6 7.1 7.4 13 6.0 0.0 5.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat SAP18 PF06487.12 OAJ20364.1 - 1.4e-14 54.5 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) UCH PF00443.29 OAJ20366.1 - 5.1e-47 160.5 0.0 6.6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ20366.1 - 3.4e-21 76.2 0.0 1e-19 71.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Clathrin_lg_ch PF01086.17 OAJ20367.1 - 2.3e-38 132.6 17.7 3.3e-37 128.7 17.7 2.3 1 1 0 1 1 1 1 Clathrin light chain Chromo PF00385.24 OAJ20368.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BUD22 PF09073.10 OAJ20369.1 - 0.013 14.9 9.8 0.018 14.4 9.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ20369.1 - 0.053 11.7 8.3 0.066 11.4 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ20369.1 - 0.19 9.8 16.3 0.26 9.3 16.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAJ20369.1 - 0.36 9.1 5.1 0.39 8.9 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein FYDLN_acid PF09538.10 OAJ20369.1 - 0.52 11.0 15.3 1.1 10.0 15.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SDA1 PF05285.12 OAJ20369.1 - 1 8.7 14.7 1.4 8.3 14.7 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OAJ20369.1 - 2.9 7.4 11.9 5.6 6.5 11.9 1.4 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 OAJ20369.1 - 3.6 7.4 7.0 5.1 6.9 7.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DDE_1 PF03184.19 OAJ20371.1 - 2.1e-19 69.9 0.4 4.1e-19 68.9 0.1 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ20371.1 - 1.2e-07 31.6 0.0 3.6e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ20371.1 - 0.0044 16.8 0.5 0.014 15.1 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease PRP1_N PF06424.12 OAJ20371.1 - 6.6 7.1 10.6 0.15 12.5 3.3 1.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PRELI PF04707.14 OAJ20373.1 - 2.2e-31 108.8 0.0 6.2e-24 84.6 0.1 2.0 2 0 0 2 2 2 2 PRELI-like family HA2 PF04408.23 OAJ20374.1 - 4.3e-24 84.9 0.2 8.4e-24 83.9 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ20374.1 - 7.6e-18 64.7 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ20374.1 - 2.4e-09 37.5 0.0 5.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ20374.1 - 5.7e-07 29.9 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ20374.1 - 6.7e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 OAJ20374.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ20374.1 - 0.015 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ20374.1 - 0.016 14.8 0.1 0.058 13.0 0.1 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 OAJ20374.1 - 0.017 15.5 0.2 0.048 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAJ20374.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ20374.1 - 0.039 13.9 0.0 7 6.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 OAJ20374.1 - 0.051 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 OAJ20374.1 - 0.061 12.7 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 OAJ20374.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OAJ20374.1 - 0.18 11.6 0.0 0.54 10.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHY PF05495.12 OAJ20376.1 - 0.04 14.4 4.5 0.1 13.1 0.1 2.3 1 1 1 2 2 2 0 CHY zinc finger Lar_restr_allev PF14354.6 OAJ20376.1 - 0.4 11.1 7.7 0.92 9.9 7.7 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar MARVEL PF01284.23 OAJ20378.1 - 2.6 8.1 11.7 0.12 12.4 0.9 3.4 3 2 0 3 3 3 0 Membrane-associating domain F-box PF00646.33 OAJ20379.1 - 2.6e-08 33.6 1.4 9e-08 31.8 1.2 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 OAJ20379.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAJ20379.1 - 0.05 13.5 0.5 0.15 12.0 0.3 1.9 2 0 0 2 2 2 0 F-box-like H_lectin PF09458.10 OAJ20380.1 - 6.9e-14 51.8 0.0 1.6e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 H-type lectin domain SnoaL_2 PF12680.7 OAJ20381.1 - 9.1e-09 35.9 0.0 1.1e-08 35.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAJ20381.1 - 7.3e-07 29.0 0.0 8.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PAT1 PF09770.9 OAJ20398.1 - 1.9e-105 354.0 67.4 1.4e-69 235.4 2.3 4.5 3 2 1 4 4 4 3 Topoisomerase II-associated protein PAT1 DUF572 PF04502.13 OAJ20398.1 - 0.12 12.0 9.6 1.7 8.2 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pyr_redox_2 PF07992.14 OAJ20399.1 - 5.1e-39 134.3 1.3 1e-37 130.0 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ20399.1 - 2.2e-18 66.3 0.0 4.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ20399.1 - 3e-15 56.5 8.5 6.9e-14 52.2 0.4 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ20399.1 - 8.9e-15 54.5 0.0 5.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 OAJ20399.1 - 1.9e-13 50.5 5.2 3.5e-10 40.1 5.2 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 OAJ20399.1 - 2.8e-11 43.2 0.3 1.5e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAJ20399.1 - 1.4e-10 40.9 0.0 2.7e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain NAD_binding_9 PF13454.6 OAJ20399.1 - 3.4e-05 23.9 2.3 0.32 11.0 0.1 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding Rubredoxin_C PF18267.1 OAJ20399.1 - 0.00016 21.5 0.0 0.17 11.8 0.0 2.9 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain DAO PF01266.24 OAJ20399.1 - 0.0059 16.2 6.2 0.072 12.7 0.2 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase TrkA_N PF02254.18 OAJ20399.1 - 0.0085 16.3 2.4 2.7 8.3 0.1 3.5 3 0 0 3 3 3 1 TrkA-N domain GIDA PF01134.22 OAJ20399.1 - 0.011 14.8 0.1 3.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 OAJ20399.1 - 0.016 15.4 0.2 0.056 13.7 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAJ20399.1 - 0.031 13.5 1.6 3.4 6.8 0.0 3.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ20399.1 - 0.073 12.1 1.8 1.5 7.8 0.1 2.7 2 1 2 4 4 4 0 FAD binding domain K_oxygenase PF13434.6 OAJ20399.1 - 0.12 11.5 0.1 6 5.9 0.1 2.8 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF2583 PF10762.9 OAJ20400.1 - 0.036 14.5 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Ribosomal_S6e PF01092.19 OAJ20401.1 - 3.5e-51 172.4 0.8 4.7e-51 172.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 OAJ20402.1 - 8.1e-31 105.9 0.4 1.3e-30 105.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAJ20402.1 - 1.7e-13 50.6 0.2 2.6e-13 50.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAJ20402.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain Lipase_3 PF01764.25 OAJ20403.1 - 9e-12 45.1 0.0 1.7e-09 37.7 0.0 2.7 3 0 0 3 3 3 2 Lipase (class 3) YjeF_N PF03853.15 OAJ20404.1 - 3e-34 118.4 0.0 4.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus HA1 PF18239.1 OAJ20404.1 - 0.085 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Hemagglutinin I PHY PF00360.20 OAJ20405.1 - 1.8e-26 92.6 0.0 4.2e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 OAJ20405.1 - 1.1e-17 64.6 0.3 1.1e-17 64.6 0.3 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ20405.1 - 5.3e-15 55.6 0.1 3e-14 53.1 0.1 2.2 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 OAJ20405.1 - 2.8e-12 47.4 0.0 8.4e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 OAJ20405.1 - 3.2e-11 43.1 0.8 8.6e-11 41.7 0.8 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 OAJ20405.1 - 6.1e-10 39.7 0.0 1.6e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 OAJ20405.1 - 0.075 12.9 1.6 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 OAJ20405.1 - 0.26 11.2 16.0 0.48 10.4 16.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serglycin PF04360.12 OAJ20405.1 - 2.2 8.2 8.8 0.26 11.2 0.8 2.6 2 0 0 2 2 2 0 Serglycin FAD_binding_8 PF08022.12 OAJ20406.1 - 4.7e-18 65.3 0.0 8.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ20406.1 - 1.6e-13 51.1 0.0 4.5e-12 46.3 0.0 2.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ20406.1 - 6.5e-12 45.7 7.7 1.4e-11 44.6 7.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component WD40 PF00400.32 OAJ20407.1 - 2e-39 132.8 28.0 1.6e-08 35.0 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ20407.1 - 2.2e-15 56.7 2.0 0.00041 20.6 0.1 6.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ20407.1 - 9.9e-13 48.4 0.6 4.9e-07 29.8 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAJ20407.1 - 0.00012 21.2 2.2 0.036 13.0 0.2 3.5 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ20407.1 - 0.0004 19.8 0.0 0.22 10.8 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 OAJ20407.1 - 0.031 12.8 0.0 0.076 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 OAJ20407.1 - 0.041 12.9 0.0 0.086 11.9 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region ADH_zinc_N PF00107.26 OAJ20408.1 - 1.1e-07 31.9 0.0 2.7e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ20408.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ20408.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAJ20408.1 - 0.0075 17.3 0.0 0.015 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAJ20409.1 - 9.1e-35 119.9 0.7 3.8e-34 117.9 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ20409.1 - 6.5e-28 97.9 0.3 9.3e-28 97.4 0.1 1.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ20409.1 - 6.2e-09 36.0 0.1 1e-08 35.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Enoyl_reductase PF12241.8 OAJ20409.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region STAG PF08514.11 OAJ20410.1 - 1.5e-32 111.9 0.3 4.6e-32 110.3 0.3 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 OAJ20410.1 - 0.076 13.3 1.0 10 6.7 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat HEPN-like_int PF18867.1 OAJ20410.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 HEPN-like integron domain Acyl-CoA_dh_2 PF08028.11 OAJ20411.1 - 2.1e-08 34.5 0.0 3.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ20411.1 - 8.9e-06 26.4 0.1 1.8e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ20411.1 - 0.0054 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ20411.1 - 0.022 15.0 0.7 0.065 13.4 0.0 2.2 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ELYS PF13934.6 OAJ20412.1 - 3.5e-07 30.4 0.0 1.3e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore complex assembly tRNA_bind PF01588.20 OAJ20413.1 - 9.3e-27 93.0 0.0 1.6e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 OAJ20413.1 - 0.0023 18.1 0.9 0.0041 17.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ20413.1 - 0.058 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MID_MedPIWI PF18296.1 OAJ20413.1 - 0.49 10.2 1.9 0.8 9.5 1.9 1.4 1 0 0 1 1 1 0 MID domain of medPIWI SRP-alpha_N PF04086.13 OAJ20413.1 - 1.7 8.5 8.2 3.2 7.6 8.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_1e PF01406.19 OAJ20414.1 - 0.8 9.0 2.6 1.2 8.5 2.6 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain ABC_tran PF00005.27 OAJ20415.1 - 1.4e-36 126.0 3.5 5.9e-20 72.2 0.0 4.3 4 1 0 4 4 3 2 ABC transporter SMC_N PF02463.19 OAJ20415.1 - 1.1e-07 31.5 0.5 0.25 10.8 0.1 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ20415.1 - 4.3e-07 30.0 4.5 0.012 15.4 0.1 4.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OAJ20415.1 - 3.7e-06 26.9 3.7 3.7e-06 26.9 3.7 2.5 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 OAJ20415.1 - 3.5e-05 23.4 0.2 0.068 12.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ20415.1 - 0.0005 20.1 0.4 0.32 11.1 0.1 3.4 4 0 0 4 4 4 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ20415.1 - 0.0005 20.0 0.4 0.029 14.3 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase SbcCD_C PF13558.6 OAJ20415.1 - 0.0027 17.9 0.0 0.16 12.3 0.0 3.2 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAJ20415.1 - 0.0036 17.8 9.4 0.56 10.7 0.1 3.5 4 0 0 4 4 3 2 AAA domain MeaB PF03308.16 OAJ20415.1 - 0.019 14.0 0.4 0.11 11.5 0.2 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 OAJ20415.1 - 0.02 15.2 0.0 5.5 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 OAJ20415.1 - 0.042 14.3 0.1 3.1 8.2 0.0 3.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 OAJ20415.1 - 0.051 13.5 0.1 0.9 9.4 0.0 2.9 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 OAJ20415.1 - 0.068 13.1 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 OAJ20415.1 - 0.11 12.1 0.0 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ20415.1 - 1.3 9.4 5.0 0.73 10.2 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain Aa_trans PF01490.18 OAJ20416.1 - 4.7e-06 25.6 0.6 0.0021 16.9 0.7 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein UPF1_Zn_bind PF09416.10 OAJ20417.1 - 2.5e-71 238.6 7.2 2.5e-71 238.6 7.2 1.6 2 0 0 2 2 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OAJ20417.1 - 9e-59 198.4 0.0 2.3e-58 197.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAJ20417.1 - 1.9e-50 172.1 3.1 3.5e-29 102.4 0.5 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OAJ20417.1 - 4e-33 113.5 0.0 8.5e-33 112.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OAJ20417.1 - 7.1e-13 48.7 0.0 3.2e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ20417.1 - 2.3e-10 41.0 0.1 7.5e-10 39.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 OAJ20417.1 - 2.5e-05 24.4 0.0 5.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAJ20417.1 - 3.8e-05 23.5 1.7 0.29 10.8 0.0 3.7 3 1 2 5 5 5 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 OAJ20417.1 - 6.4e-05 22.4 0.3 0.0032 16.8 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OAJ20417.1 - 0.00024 21.0 0.1 0.001 19.0 0.1 2.1 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 OAJ20417.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 OAJ20417.1 - 0.022 13.9 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 OAJ20417.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ20417.1 - 0.068 12.5 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_10 PF12846.7 OAJ20417.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TIP49 PF06068.13 OAJ20417.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 OAJ20417.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.29 OAJ20417.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribonuclease PF00545.20 OAJ20418.1 - 4.2e-07 30.6 0.8 5.4e-07 30.3 0.8 1.2 1 0 0 1 1 1 1 ribonuclease FAD_binding_8 PF08022.12 OAJ20419.1 - 8.3e-19 67.7 0.0 1.8e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ20419.1 - 8.6e-16 58.4 0.0 9e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ20419.1 - 6.3e-11 42.5 6.3 1.5e-10 41.3 6.3 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component HAD_2 PF13419.6 OAJ20421.1 - 4e-14 53.1 0.0 2.7e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ20421.1 - 1.2e-08 35.5 0.1 2.5e-06 28.0 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ20421.1 - 0.0087 16.5 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ20421.1 - 0.064 13.3 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAJ20421.1 - 0.2 11.8 0.0 14 5.8 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 OAJ20422.1 - 9.8e-27 94.1 0.4 2.5e-26 92.8 0.1 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 OAJ20422.1 - 4.7e-25 88.3 12.7 6.7e-25 87.7 12.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 OAJ20422.1 - 9.7e-07 28.9 0.1 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ20422.1 - 7e-05 22.5 0.5 0.00069 19.3 0.5 2.4 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ20422.1 - 0.00014 22.3 0.1 0.00028 21.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ20422.1 - 0.00049 20.0 1.0 0.0013 18.7 0.5 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ20422.1 - 0.0021 18.3 0.4 0.011 16.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAJ20422.1 - 0.011 16.2 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAJ20422.1 - 0.044 12.8 0.4 0.12 11.4 0.4 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 OAJ20422.1 - 0.057 13.3 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAJ20422.1 - 0.098 12.4 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC2_membrane PF01061.24 OAJ20424.1 - 3.9e-26 91.8 8.3 6.5e-26 91.0 8.3 1.4 1 0 0 1 1 1 1 ABC-2 type transporter FAD_binding_8 PF08022.12 OAJ20425.1 - 5.2e-17 61.9 0.0 9.3e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ20425.1 - 5.1e-14 52.7 0.0 7.3e-11 42.4 0.0 2.5 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ20425.1 - 1.1e-13 51.4 12.0 1.1e-13 51.4 9.9 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component Retrotrans_gag PF03732.17 OAJ20446.1 - 0.0087 16.3 0.2 0.022 15.0 0.0 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein RT_RNaseH_2 PF17919.1 OAJ20447.1 - 1.9e-15 56.7 0.0 8.4e-14 51.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ20447.1 - 5.8e-14 51.9 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ20447.1 - 1.3e-10 41.5 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ20447.1 - 0.00025 21.3 0.0 0.017 15.4 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ20447.1 - 0.0057 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Ribosomal_L18 PF17135.4 OAJ20449.1 - 1.1e-90 302.1 2.4 1.3e-90 301.9 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAJ20449.1 - 0.00028 21.5 0.0 0.00066 20.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adap_comp_sub PF00928.21 OAJ20450.1 - 1.2e-92 310.0 0.0 2.2e-92 309.2 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ20450.1 - 8e-08 32.3 0.1 1.4e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 OAJ20450.1 - 0.05 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF883 PF05957.13 OAJ20451.1 - 0.046 14.3 3.9 0.074 13.7 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.6 OAJ20451.1 - 1.8 8.2 3.8 2.6 7.7 1.0 2.5 2 0 0 2 2 2 0 FAM176 family SUR7 PF06687.12 OAJ20452.1 - 3.5e-17 62.8 7.6 5.1e-17 62.2 7.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 OAJ20452.1 - 1.9e-11 44.1 1.1 1.9e-11 44.1 1.1 2.2 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction V_ATPase_I PF01496.19 OAJ20452.1 - 0.016 13.2 0.1 0.03 12.2 0.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2254 PF10011.9 OAJ20452.1 - 0.077 11.8 3.7 0.07 11.9 1.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF2070 PF09843.9 OAJ20452.1 - 0.12 10.7 10.7 0.22 9.8 10.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SPC25 PF06703.11 OAJ20452.1 - 0.21 11.4 0.8 0.35 10.6 0.8 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SLATT_3 PF18184.1 OAJ20452.1 - 2.6 8.2 6.1 5.1 7.2 6.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 RRM_1 PF00076.22 OAJ20453.1 - 1.2e-13 50.6 0.0 1.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nse4_C PF08743.10 OAJ20454.1 - 3.9e-29 100.7 0.1 1.2e-28 99.1 0.1 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAJ20454.1 - 1e-09 38.4 0.6 2.3e-09 37.2 0.6 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1351 PF07083.11 OAJ20454.1 - 0.0094 15.7 0.8 0.0094 15.7 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1351) Cation_efflux PF01545.21 OAJ20455.1 - 7e-20 71.6 7.0 8.7e-20 71.3 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ20455.1 - 8.7e-09 35.4 0.4 1.4e-08 34.8 0.4 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter TctB PF07331.11 OAJ20455.1 - 1.3 9.3 7.9 1.3 9.3 3.3 2.3 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ECH_1 PF00378.20 OAJ20456.1 - 5.7e-38 130.7 0.1 2.1e-37 128.8 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ20456.1 - 1.1e-19 71.1 0.2 3e-18 66.4 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF334 PF03904.13 OAJ20456.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Snf7 PF03357.21 OAJ20457.1 - 1.3e-45 155.1 12.6 1.5e-45 154.9 12.6 1.0 1 0 0 1 1 1 1 Snf7 NuA4 PF09340.10 OAJ20457.1 - 0.02 14.8 1.3 0.27 11.1 0.2 2.7 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DMPK_coil PF08826.10 OAJ20457.1 - 0.047 13.8 0.3 0.047 13.8 0.3 3.4 4 0 0 4 4 4 0 DMPK coiled coil domain like UDPG_MGDP_dh_N PF03721.14 OAJ20457.1 - 0.13 11.8 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Uso1_p115_C PF04871.13 OAJ20457.1 - 0.17 12.3 13.4 0.39 11.1 8.7 2.7 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 OAJ20457.1 - 0.47 8.3 6.6 0.62 7.9 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.9 OAJ20457.1 - 1.1 9.5 9.9 1.4e+02 2.7 9.9 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein Prefoldin_2 PF01920.20 OAJ20457.1 - 2 8.4 16.8 8.6 6.4 0.1 3.6 2 1 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 OAJ20457.1 - 2.1 8.8 6.3 23 5.5 0.0 3.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF848 PF05852.11 OAJ20457.1 - 2.3 8.3 9.2 1.2 9.2 6.1 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FapA PF03961.13 OAJ20457.1 - 4.7 5.7 8.3 1.6 7.3 3.4 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A ADH_N PF08240.12 OAJ20459.1 - 2e-28 98.4 1.0 2e-28 98.4 1.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ20459.1 - 7.3e-24 84.2 0.1 1.3e-23 83.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ20459.1 - 0.00044 19.8 0.1 0.00071 19.1 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 OAJ20459.1 - 0.0015 19.6 0.2 0.0032 18.5 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAJ20459.1 - 0.0083 15.6 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 OAJ20459.1 - 0.042 13.3 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3794 PF12673.7 OAJ20459.1 - 0.15 12.3 0.0 0.62 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3794) DNA_binding_1 PF01035.20 OAJ20460.1 - 1.3e-22 79.7 0.2 1.9e-22 79.2 0.2 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 OAJ20460.1 - 0.058 13.3 0.0 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Actin PF00022.19 OAJ20463.1 - 9e-24 83.8 0.0 2e-19 69.5 0.0 3.3 4 0 0 4 4 4 3 Actin Asn_synthase PF00733.21 OAJ20464.1 - 5e-17 62.6 2.4 1.1e-08 35.2 1.1 3.2 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAJ20464.1 - 1.6e-10 40.9 0.0 3.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAJ20464.1 - 3.5e-09 37.0 0.0 7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAJ20464.1 - 0.028 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein NAD_synthase PF02540.17 OAJ20464.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 OAJ20464.1 - 0.19 11.2 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF413 PF04219.12 OAJ20466.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF GATA PF00320.27 OAJ20467.1 - 6.3e-05 22.5 5.2 0.00019 21.0 4.2 2.1 1 1 1 2 2 2 1 GATA zinc finger ADK_lid PF05191.14 OAJ20467.1 - 0.22 11.5 1.9 0.44 10.6 1.9 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid Glyco_hydro_92 PF07971.12 OAJ20468.1 - 1.3e-105 354.0 0.0 1.8e-105 353.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ20468.1 - 3.1e-41 141.8 0.4 4.8e-41 141.2 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain tRNA-synt_1c PF00749.21 OAJ20469.1 - 3.8e-73 246.1 0.0 5.2e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain UAA PF08449.11 OAJ20470.1 - 6.9e-39 133.8 10.6 1.1e-37 130.0 10.4 2.2 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.20 OAJ20470.1 - 1.5e-05 25.2 5.7 1.5e-05 25.2 5.7 4.4 3 2 1 4 4 4 1 EamA-like transporter family TMEM234 PF10639.9 OAJ20470.1 - 0.004 17.2 2.5 1.4 9.0 0.1 2.5 2 0 0 2 2 2 2 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 OAJ20470.1 - 0.0061 15.8 6.0 0.29 10.3 0.1 2.5 3 0 0 3 3 3 2 Nucleotide-sugar transporter CRT-like PF08627.10 OAJ20470.1 - 0.016 14.2 4.4 0.55 9.1 0.2 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 OAJ20470.1 - 0.021 14.2 9.5 0.24 10.7 1.8 2.7 3 1 0 3 3 3 0 Triose-phosphate Transporter family ESSS PF10183.9 OAJ20471.1 - 4.3e-08 33.3 0.1 5.9e-08 32.9 0.1 1.3 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3667 PF12412.8 OAJ20471.1 - 0.0027 17.2 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3667) DUF3432 PF11914.8 OAJ20471.1 - 0.015 15.5 6.0 0.035 14.4 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Suc_Fer-like PF06999.12 OAJ20471.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Sucrase/ferredoxin-like MDM31_MDM32 PF08118.11 OAJ20473.1 - 1.2e-178 595.1 0.0 3.4e-178 593.6 0.0 1.7 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins EthD PF07110.11 OAJ20474.1 - 0.0016 19.6 0.5 0.67 11.1 0.2 2.4 2 0 0 2 2 2 2 EthD domain UDPGP PF01704.18 OAJ20475.1 - 2.2e-201 668.9 0.1 2.5e-201 668.7 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MFS_1 PF07690.16 OAJ20476.1 - 4.1e-28 98.3 25.0 5.3e-28 97.9 25.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ20476.1 - 0.0048 15.8 7.8 0.0072 15.2 7.8 1.2 1 0 0 1 1 1 1 MFS_1 like family SNF2_N PF00176.23 OAJ20478.1 - 1.8e-56 191.4 21.3 2.4e-36 125.2 0.3 3.8 2 1 1 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ20478.1 - 4.2e-15 56.0 0.0 1.5e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 OAJ20479.1 - 8.3e-52 175.1 0.0 9.4e-39 132.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 OAJ20479.1 - 1.7e-09 37.3 0.3 8.7e-08 31.8 0.0 3.0 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 OAJ20479.1 - 1e-08 34.8 0.1 2.4e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ20479.1 - 1e-07 32.3 0.1 2.4e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ20479.1 - 1.1e-07 32.4 0.0 0.0093 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 OAJ20479.1 - 3.5e-07 30.1 0.2 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ20479.1 - 4.5e-07 30.2 0.0 0.00014 22.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ20479.1 - 8.7e-07 28.5 0.1 0.03 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OAJ20479.1 - 5.5e-06 26.6 0.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ20479.1 - 6.8e-06 26.1 0.0 0.0026 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ20479.1 - 7.7e-06 26.5 0.0 0.026 15.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 OAJ20479.1 - 1.4e-05 24.6 0.3 0.0076 15.6 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ20479.1 - 7.2e-05 22.6 0.0 0.062 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ20479.1 - 0.00011 22.2 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 OAJ20479.1 - 0.00013 22.0 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 OAJ20479.1 - 0.00013 21.1 0.0 0.08 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 OAJ20479.1 - 0.00014 22.2 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 OAJ20479.1 - 0.00027 21.2 0.0 0.69 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ20479.1 - 0.0003 20.6 0.2 0.048 13.4 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 OAJ20479.1 - 0.0019 17.6 0.5 0.015 14.7 0.1 2.2 2 0 0 2 2 2 1 KaiC KTI12 PF08433.10 OAJ20479.1 - 0.0022 17.5 0.1 0.79 9.1 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 OAJ20479.1 - 0.0022 17.7 0.0 0.95 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 OAJ20479.1 - 0.0023 18.4 0.4 0.046 14.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 OAJ20479.1 - 0.0032 17.0 2.0 0.032 13.7 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 OAJ20479.1 - 0.004 16.8 0.2 2.8 7.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 OAJ20479.1 - 0.0044 16.9 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 OAJ20479.1 - 0.0053 16.9 0.0 0.026 14.7 0.0 2.2 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 OAJ20479.1 - 0.0074 16.2 1.6 2.6 7.9 0.0 3.2 4 0 0 4 4 3 1 NACHT domain CPT PF07931.12 OAJ20479.1 - 0.01 15.7 0.1 0.096 12.5 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 OAJ20479.1 - 0.015 15.1 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAJ20479.1 - 0.018 14.9 0.3 28 4.5 0.0 3.4 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 OAJ20479.1 - 0.022 14.5 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ20479.1 - 0.022 14.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Hydin_ADK PF17213.3 OAJ20479.1 - 0.042 14.1 0.4 0.49 10.7 0.2 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 OAJ20479.1 - 0.063 12.3 0.1 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 OAJ20479.1 - 0.067 12.6 0.5 1.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 OAJ20479.1 - 0.079 13.4 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ20479.1 - 0.086 12.0 0.2 9 5.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 OAJ20479.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ20479.1 - 0.3 11.4 2.4 1.4 9.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain Myb_DNA-binding PF00249.31 OAJ20480.1 - 4.6e-11 42.7 0.7 1.1e-10 41.5 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ20480.1 - 3.1e-07 30.6 0.6 7.2e-07 29.4 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ20480.1 - 0.046 13.6 0.3 0.085 12.8 0.3 1.4 1 0 0 1 1 1 0 Myb DNA-binding like JAKMIP_CC3 PF16034.5 OAJ20480.1 - 0.22 11.4 6.9 0.43 10.5 3.6 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain SOCS PF12610.8 OAJ20480.1 - 2.3 8.7 6.9 0.43 11.0 0.6 3.1 2 0 0 2 2 2 0 Suppressor of cytokine signalling Dynactin_p22 PF07426.11 OAJ20481.1 - 2.6e-10 40.4 0.1 1.1e-07 31.8 0.0 2.9 2 1 0 2 2 2 2 Dynactin subunit p22 Pox_A_type_inc PF04508.12 OAJ20481.1 - 0.0049 16.6 3.6 0.88 9.5 0.2 2.4 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Lebercilin PF15619.6 OAJ20481.1 - 0.086 12.5 0.6 0.18 11.4 0.6 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease RVT_1 PF00078.27 OAJ20482.1 - 5.3e-23 81.7 0.0 8.8e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ20482.1 - 3.4e-06 27.6 1.0 3.4e-05 24.4 0.1 2.7 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ20482.1 - 0.013 16.0 0.1 0.054 14.1 0.0 2.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ20482.1 - 0.2 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease tRNA-synt_2d PF01409.20 OAJ20483.1 - 7.8e-44 150.0 0.1 1.8e-25 89.9 0.1 2.8 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAJ20483.1 - 8.4e-24 83.8 0.0 2.1e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain FeS_assembly_P PF01883.19 OAJ20495.1 - 1.1e-11 44.7 0.0 2.2e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein AAA PF00004.29 OAJ20496.1 - 5.2e-31 107.8 0.0 1.2e-30 106.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ20496.1 - 2.5e-07 31.0 0.7 1.2e-06 28.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAJ20496.1 - 1e-06 29.3 0.0 2.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OAJ20496.1 - 5.6e-06 26.6 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ20496.1 - 1.9e-05 24.9 0.1 8.7e-05 22.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 OAJ20496.1 - 2.4e-05 24.9 0.0 5.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAJ20496.1 - 2.8e-05 24.1 0.1 0.015 15.2 0.1 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAJ20496.1 - 4.5e-05 23.1 0.1 0.19 11.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain NACHT PF05729.12 OAJ20496.1 - 0.00029 20.8 0.2 0.0028 17.6 0.2 2.3 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 OAJ20496.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ20496.1 - 0.0007 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ20496.1 - 0.0029 17.4 0.1 0.0086 15.8 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 OAJ20496.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 OAJ20496.1 - 0.0035 17.1 0.1 0.0085 15.8 0.1 1.8 1 1 0 1 1 1 1 Cytidylate kinase RNA_helicase PF00910.22 OAJ20496.1 - 0.0036 17.7 0.0 0.0081 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 OAJ20496.1 - 0.0036 17.3 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAJ20496.1 - 0.0037 17.3 0.1 0.0079 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAJ20496.1 - 0.0039 17.0 2.6 0.0042 16.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 OAJ20496.1 - 0.0042 16.6 0.0 0.47 9.9 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_28 PF13521.6 OAJ20496.1 - 0.0053 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ20496.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OAJ20496.1 - 0.0072 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OAJ20496.1 - 0.0084 15.3 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAJ20496.1 - 0.016 14.4 0.0 1.1 8.5 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 OAJ20496.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 OAJ20496.1 - 0.029 14.9 0.1 0.077 13.5 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.21 OAJ20496.1 - 0.031 13.6 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ20496.1 - 0.034 14.5 0.4 0.2 12.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 OAJ20496.1 - 0.04 13.4 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 OAJ20496.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAJ20496.1 - 0.065 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 OAJ20496.1 - 0.082 12.1 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 OAJ20496.1 - 0.088 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 OAJ20496.1 - 0.1 13.1 0.1 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 OAJ20496.1 - 0.11 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_3 PF07726.11 OAJ20496.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 OAJ20496.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2407_C PF13373.6 OAJ20497.1 - 5.2e-12 46.1 3.6 1.9e-11 44.3 1.6 2.7 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAJ20497.1 - 2.1e-11 44.3 2.6 2.2e-10 41.0 0.8 2.7 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAJ20497.1 - 0.004 16.9 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 OAJ20498.1 - 9.8e-18 63.8 0.0 1.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ20498.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ20498.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 RL domain FBPase PF00316.20 OAJ20499.1 - 4.9e-74 247.9 0.4 6.2e-74 247.6 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OAJ20499.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family eRF1_1 PF03463.15 OAJ20501.1 - 2.2e-50 170.0 0.0 3.2e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 OAJ20501.1 - 6.6e-23 81.4 0.0 1.2e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 OAJ20501.1 - 3.7e-20 72.6 0.0 5.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_anti-codon PF01336.25 OAJ20501.1 - 0.11 12.5 0.1 0.47 10.5 0.0 2.1 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain BSP_II PF05432.11 OAJ20502.1 - 1.3 8.6 36.1 1.7 8.3 36.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SURF2 PF05477.11 OAJ20502.1 - 6.6 6.4 20.1 8.2 6.0 20.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) IF4E PF01652.18 OAJ20503.1 - 6.9e-46 155.9 0.0 1e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E BRF1 PF07741.13 OAJ20503.1 - 0.14 12.5 7.8 3.4 8.1 0.1 2.7 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Spt20 PF12090.8 OAJ20503.1 - 0.23 11.0 9.8 0.37 10.4 9.8 1.3 1 0 0 1 1 1 0 Spt20 family MPM1 PF17234.2 OAJ20503.1 - 0.28 11.4 6.1 0.64 10.3 6.1 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Apolipoprotein PF01442.18 OAJ20504.1 - 7.6e-05 22.7 0.4 0.00013 21.9 0.4 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Collagen_mid PF15984.5 OAJ20504.1 - 0.00089 19.1 0.9 0.0023 17.7 0.9 1.8 1 1 0 1 1 1 1 Bacterial collagen, middle region Baculo_PEP_C PF04513.12 OAJ20504.1 - 0.0028 17.7 7.5 0.24 11.4 1.5 2.9 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 OAJ20504.1 - 0.036 14.1 1.2 0.085 13.0 0.5 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) KxDL PF10241.9 OAJ20504.1 - 0.049 13.9 0.2 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein RRF PF01765.19 OAJ20504.1 - 0.052 13.5 0.2 0.088 12.8 0.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Serine_rich PF08824.10 OAJ20504.1 - 0.069 13.2 0.2 0.31 11.0 0.2 2.0 1 1 0 1 1 1 0 Serine rich protein interaction domain CagS PF16707.5 OAJ20504.1 - 0.089 12.8 0.2 0.58 10.1 0.1 1.9 1 1 1 2 2 2 0 Cag pathogenicity island protein S of Helicobacter pylori Tape_meas_lam_C PF09718.10 OAJ20504.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) AIP3 PF03915.13 OAJ20504.1 - 0.14 11.2 1.3 0.18 10.9 1.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 ATP-cone PF03477.16 OAJ20504.1 - 0.66 10.6 2.7 33 5.2 2.2 3.1 2 1 0 2 2 2 0 ATP cone domain DEAD PF00270.29 OAJ20506.1 - 6.1e-34 117.3 0.2 8.4e-33 113.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20506.1 - 3.7e-28 98.1 0.1 6.8e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ20506.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain CDC27 PF09507.10 OAJ20507.1 - 9.3e-28 97.8 69.7 1.7e-18 67.2 0.0 4.0 2 1 1 3 3 3 3 DNA polymerase subunit Cdc27 Myc_N PF01056.18 OAJ20507.1 - 0.05 13.5 22.2 0.087 12.7 22.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region F-protein PF00469.20 OAJ20507.1 - 3 7.4 13.2 6 6.4 13.2 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef AFG1_ATPase PF03969.16 OAJ20508.1 - 1.2e-85 287.6 0.0 1.3e-82 277.6 0.0 2.7 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAJ20508.1 - 2.8e-06 27.8 0.0 7.2e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ20508.1 - 0.00066 20.0 0.0 0.0045 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ20508.1 - 0.011 16.1 0.1 0.13 12.7 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LIME1 PF15332.6 OAJ20508.1 - 0.018 14.6 0.0 0.079 12.5 0.0 1.9 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 UvrD-helicase PF00580.21 OAJ20508.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Antimicrobial19 PF08225.11 OAJ20508.1 - 0.16 11.6 0.4 0.37 10.5 0.4 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DEAD PF00270.29 OAJ20509.1 - 9.1e-45 152.6 0.0 2.6e-44 151.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20509.1 - 7.1e-27 93.9 0.0 5.4e-26 91.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20509.1 - 0.00016 21.7 0.0 0.00049 20.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2285 PF10074.9 OAJ20509.1 - 0.027 15.1 2.6 0.34 11.6 0.9 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) Rrp44_CSD1 PF17216.3 OAJ20509.1 - 0.057 13.1 0.2 0.16 11.7 0.2 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain CMS1 PF14617.6 OAJ20509.1 - 0.063 12.6 0.9 0.15 11.4 0.0 2.1 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC PF00098.23 OAJ20509.1 - 0.73 10.0 2.6 1.3 9.2 2.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Mcm10 PF09332.11 OAJ20509.1 - 5.2 6.4 8.6 8.1 5.8 8.6 1.2 1 0 0 1 1 1 0 Mcm10 replication factor AD PF09793.9 OAJ20510.1 - 1.1e-18 67.1 0.0 1.8e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain SUI1 PF01253.22 OAJ20511.1 - 4.5e-22 78.4 0.0 1.1e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAJ20511.1 - 3.3e-11 43.7 0.3 7.2e-08 33.0 0.0 3.2 3 0 0 3 3 3 2 Pre-PUA-like domain BAF1_ABF1 PF04684.13 OAJ20511.1 - 0.0053 15.9 2.2 0.0081 15.3 2.2 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Peptidase_C37 PF05416.12 OAJ20511.1 - 0.67 8.4 4.2 1.2 7.5 4.2 1.4 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Glyco_hydro_cc PF11790.8 OAJ20512.1 - 5.2e-47 160.4 4.0 6e-47 160.2 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GATase PF00117.28 OAJ20513.1 - 6.1e-08 32.7 0.0 1.3e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAJ20513.1 - 0.08 12.7 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase C26 Chromate_transp PF02417.15 OAJ20514.1 - 2.7e-58 196.5 30.3 1.6e-33 116.1 11.0 2.5 3 0 0 3 3 3 2 Chromate transporter Sugar_tr PF00083.24 OAJ20515.1 - 6.5e-29 101.1 22.5 2.8e-18 66.0 10.5 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20515.1 - 1.1e-14 54.2 46.7 3.2e-08 32.9 26.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RNase_T PF00929.24 OAJ20516.1 - 1e-20 74.9 0.2 2.2e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Exonuclease DUF4363 PF14276.6 OAJ20516.1 - 0.19 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Na_Ala_symp PF01235.17 OAJ20516.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family PUL PF08324.11 OAJ20517.1 - 3.8e-43 147.7 0.7 5.3e-43 147.2 0.7 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 OAJ20517.1 - 1.4e-42 144.5 0.0 2.9e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 OAJ20517.1 - 4.5e-28 96.9 13.7 2.3e-05 25.1 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAJ20517.1 - 0.0072 16.4 0.0 3.2 7.8 0.0 3.6 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Asp PF00026.23 OAJ20518.1 - 4.6e-55 187.3 1.6 1.7e-54 185.4 1.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ20518.1 - 1.8e-11 44.6 1.0 9.6e-06 25.9 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ20518.1 - 1.7e-06 27.9 0.0 4.6e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ20518.1 - 0.0006 20.4 0.5 0.54 10.9 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ20518.1 - 0.06 13.9 0.0 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MucBP_2 PF17965.1 OAJ20519.1 - 0.076 13.6 0.3 0.19 12.4 0.3 1.6 1 0 0 1 1 1 0 Mucin binding domain Peptidase_M26_N PF05342.14 OAJ20520.1 - 0.093 12.1 0.0 0.46 9.9 0.0 1.8 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region ThiF PF00899.21 OAJ20521.1 - 8.6e-104 346.2 0.0 4.4e-70 235.8 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAJ20521.1 - 1.8e-92 309.8 0.1 3.2e-92 309.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OAJ20521.1 - 1.1e-34 118.4 0.4 2.7e-34 117.2 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OAJ20521.1 - 2.1e-31 108.4 0.0 4.7e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OAJ20521.1 - 1.3e-25 89.3 0.1 3.1e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Sugar_tr PF00083.24 OAJ20522.1 - 3.4e-29 102.0 15.3 1.1e-16 60.7 9.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ20522.1 - 2e-11 43.4 44.9 4.3e-10 39.1 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 OAJ20523.1 - 2.1e-42 145.4 2.5 2.7e-42 145.0 2.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAJ20523.1 - 6.1e-17 61.4 0.0 1.4e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAJ20523.1 - 1.2e-12 48.2 9.1 2.2e-11 44.1 0.5 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ20523.1 - 3.3e-08 33.4 0.0 1.3e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 OAJ20523.1 - 0.0037 17.8 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 OAJ20523.1 - 0.011 14.9 0.2 4.3 6.4 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1344 PF07076.11 OAJ20523.1 - 0.089 12.7 0.1 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) Amino_oxidase PF01593.24 OAJ20523.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 OAJ20523.1 - 0.11 12.5 0.4 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAJ20523.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.9 3 0 0 3 3 3 0 HI0933-like protein KAR9 PF08580.10 OAJ20524.1 - 3.7e-12 45.6 20.4 3.7e-12 45.6 20.4 5.2 2 1 0 3 3 3 1 Yeast cortical protein KAR9 GAS2 PF02187.17 OAJ20524.1 - 0.012 15.7 0.3 0.031 14.4 0.3 1.6 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain VIT1 PF01988.19 OAJ20525.1 - 2.5e-59 200.8 3.3 3e-59 200.5 3.3 1.1 1 0 0 1 1 1 1 VIT family Peptidase_M20 PF01546.28 OAJ20526.1 - 7.2e-22 78.1 6.1 1.5e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 OAJ20526.1 - 1e-15 57.8 13.3 3.4e-05 24.5 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat M20_dimer PF07687.14 OAJ20526.1 - 6.7e-09 35.6 2.5 8.5e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 OAJ20526.1 - 1.9e-05 24.8 0.3 0.12 12.7 0.1 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 OAJ20526.1 - 0.00035 19.5 0.4 0.0082 14.9 0.2 2.6 2 1 0 2 2 2 1 Nup133 N terminal like RNA_pol_Rpc34 PF05158.12 OAJ20527.1 - 1.2e-76 258.3 9.8 2.2e-69 234.4 0.5 3.3 2 1 1 3 3 3 3 RNA polymerase Rpc34 subunit TrmB PF01978.19 OAJ20527.1 - 0.081 12.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Cation_efflux PF01545.21 OAJ20528.1 - 7.2e-40 136.8 7.0 6.2e-39 133.8 7.0 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ20528.1 - 4.5e-09 36.3 0.8 1.3e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter LEA_2 PF03168.13 OAJ20529.1 - 0.062 13.8 0.0 0.18 12.3 0.0 1.8 1 1 1 2 2 2 0 Late embryogenesis abundant protein Neurensin PF14927.6 OAJ20529.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Neurensin Glyco_hydro_5_C PF18564.1 OAJ20530.1 - 6.7e-11 42.6 0.0 4.5e-09 36.7 0.0 2.8 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ20530.1 - 3.4e-08 33.3 0.0 9.8e-07 28.5 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Acyltransferase PF01553.21 OAJ20531.1 - 5.1e-17 61.7 0.1 8.8e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase FA_desaturase PF00487.24 OAJ20531.1 - 0.091 12.6 5.5 0.18 11.6 5.5 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Sas10_Utp3 PF04000.15 OAJ20547.1 - 2.1e-13 50.7 0.1 5.6e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CENP-B_dimeris PF09026.10 OAJ20547.1 - 0.29 11.6 12.4 0.48 10.8 9.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRN3 PF05327.11 OAJ20547.1 - 0.44 9.0 1.7 0.66 8.4 1.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 OAJ20547.1 - 1.2 6.8 2.9 2 6.1 2.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 OAJ20547.1 - 1.4 6.9 13.9 2 6.4 13.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 OAJ20547.1 - 2.3 8.5 14.9 0.36 11.1 5.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) SRAP PF02586.14 OAJ20548.1 - 2.8e-56 190.5 0.0 4.1e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Totivirus_coat PF05518.11 OAJ20548.1 - 9.7 4.1 7.0 14 3.6 7.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein Amastin PF07344.11 OAJ20549.1 - 0.8 9.5 13.6 0.029 14.2 6.8 1.9 2 1 0 2 2 2 0 Amastin surface glycoprotein LNS2 PF08235.13 OAJ20550.1 - 2e-96 321.8 0.0 1.1e-75 254.0 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAJ20550.1 - 1.9e-30 104.8 0.1 6.2e-29 100.0 0.1 2.4 1 1 0 1 1 1 1 lipin, N-terminal conserved region WRNPLPNID PF15017.6 OAJ20550.1 - 0.029 15.3 0.1 0.029 15.3 0.1 2.8 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Acid_phosphat_B PF03767.14 OAJ20550.1 - 0.037 13.6 0.1 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) zf-H2C2 PF09337.10 OAJ20550.1 - 0.17 12.1 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 H2C2 zinc finger Transferase PF02458.15 OAJ20551.1 - 5.3e-06 25.3 0.0 1.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Transferase family MFS_1 PF07690.16 OAJ20552.1 - 2.1e-16 59.8 38.9 2.1e-16 59.8 38.9 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5367 PF17329.2 OAJ20552.1 - 0.00082 19.4 2.7 0.00082 19.4 2.7 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5367) Sugar_tr PF00083.24 OAJ20552.1 - 0.97 8.2 30.4 0.0075 15.2 13.6 2.8 2 1 0 2 2 2 0 Sugar (and other) transporter ADH_zinc_N_2 PF13602.6 OAJ20553.1 - 3.2e-22 80.0 0.0 1.1e-21 78.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ20553.1 - 1.8e-14 53.9 0.0 5e-14 52.4 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ20553.1 - 1.2e-05 25.1 0.0 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RTBV_P12 PF06361.11 OAJ20553.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein ADH_N_2 PF16884.5 OAJ20553.1 - 0.042 13.8 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase CTP_transf_like PF01467.26 OAJ20554.1 - 1e-25 90.6 0.0 1.7e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Lipase_3 PF01764.25 OAJ20556.1 - 0.0091 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ20556.1 - 0.0092 15.3 0.0 0.025 13.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ20556.1 - 0.16 12.6 2.8 0.097 13.3 0.2 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 OAJ20557.1 - 0.017 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ20557.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAJ20557.1 - 0.14 11.9 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein DUF915 PF06028.11 OAJ20557.1 - 0.15 11.4 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 OAJ20557.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pirin PF02678.16 OAJ20558.1 - 5.9e-28 97.0 0.1 1.2e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OAJ20558.1 - 1.7e-23 82.9 0.0 6.6e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAJ20558.1 - 0.0073 16.0 1.4 0.034 13.9 0.9 2.2 2 0 0 2 2 2 1 Cupin domain Pro_isomerase PF00160.21 OAJ20559.1 - 4.7e-27 95.2 0.0 7.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAJ20559.1 - 4.8e-15 55.1 0.0 8.2e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATA PF00320.27 OAJ20561.1 - 1.7e-13 49.9 3.7 3.1e-13 49.1 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAJ20561.1 - 6.5e-10 39.0 0.0 6.5e-10 39.0 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.12 OAJ20561.1 - 3e-07 30.6 0.0 3.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAJ20561.1 - 0.00096 19.4 1.2 0.0059 16.8 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAJ20561.1 - 0.0016 18.7 2.0 0.0023 18.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain MecA PF05389.12 OAJ20561.1 - 0.02 14.6 11.6 0.16 11.6 2.5 2.7 3 0 0 3 3 3 0 Negative regulator of genetic competence (MecA) TF_Zn_Ribbon PF08271.12 OAJ20561.1 - 0.038 13.5 0.7 0.13 11.8 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding HNOBA PF07701.14 OAJ20561.1 - 0.081 12.3 10.8 0.48 9.8 0.2 2.3 2 0 0 2 2 2 0 Heme NO binding associated ArfGap PF01412.18 OAJ20561.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.3 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf KfrA_N PF11740.8 OAJ20561.1 - 0.87 10.3 34.6 1.9 9.2 11.2 2.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Connexin PF00029.19 OAJ20561.1 - 2.2 8.0 17.1 0.47 10.2 2.9 2.4 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 OAJ20561.1 - 2.2 8.0 29.6 0.3 10.9 5.9 3.4 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 ABC2_membrane_2 PF12679.7 OAJ20561.1 - 2.9 7.1 6.3 9.3 5.4 0.9 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein CNDH2_C PF16858.5 OAJ20561.1 - 8.6 6.1 26.9 0.46 10.3 6.0 2.8 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mtr2 PF10429.9 OAJ20562.1 - 0.01 15.7 0.0 0.13 12.2 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.20 OAJ20562.1 - 0.056 14.0 0.0 0.66 10.6 0.0 2.5 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain PCI PF01399.27 OAJ20563.1 - 6.4e-10 39.5 0.2 2.4e-09 37.6 0.2 2.1 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.13 OAJ20563.1 - 0.16 11.6 7.0 0.99 9.1 0.0 3.9 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF882) DnaJ PF00226.31 OAJ20564.1 - 4.2e-18 65.2 0.1 7.1e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain TMEM154 PF15102.6 OAJ20565.1 - 0.00025 21.0 0.0 0.00025 21.0 0.0 2.5 1 1 1 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 OAJ20565.1 - 0.011 14.6 0.1 0.015 14.1 0.1 1.2 1 0 0 1 1 1 0 Amnionless Gly-zipper_Omp PF13488.6 OAJ20565.1 - 0.025 14.6 2.4 0.025 14.6 2.4 4.8 5 0 0 5 5 5 0 Glycine zipper RIFIN PF02009.16 OAJ20565.1 - 0.068 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Rifin Syndecan PF01034.20 OAJ20565.1 - 0.092 12.7 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 OAJ20565.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Stevor PF17410.2 OAJ20565.1 - 0.72 9.3 1.6 1.3 8.5 1.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Beta-APP PF03494.13 OAJ20565.1 - 1.7 8.5 4.7 3.9 7.4 4.7 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Metallophos PF00149.28 OAJ20566.1 - 1.3e-28 100.9 0.0 2.9e-27 96.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OAJ20566.1 - 5.4e-19 68.3 0.0 8.5e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 PPP5 TPR repeat region FA_desaturase PF00487.24 OAJ20567.1 - 1.2e-22 81.0 26.4 1.4e-21 77.5 26.4 2.1 1 1 0 1 1 1 1 Fatty acid desaturase HSF_DNA-bind PF00447.17 OAJ20568.1 - 2.5e-31 108.2 0.1 2.5e-31 108.2 0.1 2.3 3 0 0 3 3 3 1 HSF-type DNA-binding Peptidase_M24 PF00557.24 OAJ20570.1 - 7.7e-45 153.1 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 OAJ20570.1 - 8.2e-07 29.7 0.0 1.7e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Methyltr_RsmB-F PF01189.17 OAJ20571.1 - 2.5e-17 63.2 0.0 5.9e-08 32.6 0.0 3.4 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F HWE_HK PF07536.14 OAJ20571.1 - 0.2 12.4 1.5 0.33 11.7 0.1 2.1 2 0 0 2 2 2 0 HWE histidine kinase DUF4710 PF15828.5 OAJ20571.1 - 5.2 7.3 9.3 90 3.3 7.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF1752 PF08550.10 OAJ20572.1 - 3.2e-11 42.8 4.7 7.4e-11 41.7 4.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 OAJ20573.1 - 2.3e-36 125.5 14.3 3.4e-36 124.9 14.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ20573.1 - 1.3e-08 34.2 1.8 1.3e-08 34.2 1.8 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ20573.1 - 0.00088 17.8 1.8 0.0017 16.9 1.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 OAJ20573.1 - 0.045 14.0 0.3 0.23 11.7 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) MFS_3 PF05977.13 OAJ20573.1 - 0.19 10.1 5.7 0.051 12.0 1.2 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Glyco_hydro_18 PF00704.28 OAJ20574.1 - 1.6e-81 274.5 0.3 1.8e-81 274.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MAPEG PF01124.18 OAJ20575.1 - 9.7e-26 90.2 2.2 1.1e-25 90.0 2.2 1.0 1 0 0 1 1 1 1 MAPEG family DUF202 PF02656.15 OAJ20576.1 - 2.7e-21 75.8 0.4 2.7e-21 75.8 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2583 PF10762.9 OAJ20576.1 - 0.11 12.9 0.9 0.26 11.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) DUF572 PF04502.13 OAJ20577.1 - 3.2 7.3 33.7 7.3 6.1 33.7 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Na_H_Exchanger PF00999.21 OAJ20578.1 - 2.2e-40 138.6 23.9 2.8e-40 138.3 23.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_3_3 PF16083.5 OAJ20578.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.2 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III LsmAD PF06741.13 OAJ20579.1 - 2e-25 89.1 0.6 2e-25 89.1 0.6 1.8 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 OAJ20579.1 - 1.9e-12 47.1 0.0 3.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain L31 PF09784.9 OAJ20580.1 - 1.5e-42 144.2 0.7 1.6e-42 144.0 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 SLBP_RNA_bind PF15247.6 OAJ20580.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.6 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Glyco_trans_2_3 PF13632.6 OAJ20599.1 - 3.7e-08 33.5 0.2 3.7e-08 33.5 0.2 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulase PF00150.18 OAJ20600.1 - 1.1e-28 100.5 0.1 1.4e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Aminotran_5 PF00266.19 OAJ20601.1 - 4.3e-33 114.8 0.2 1.1e-25 90.4 0.1 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ20601.1 - 2.3e-05 23.1 0.0 8.3e-05 21.3 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme UbiA PF01040.18 OAJ20602.1 - 7e-48 163.1 23.6 1.9e-46 158.4 19.1 2.1 2 0 0 2 2 2 2 UbiA prenyltransferase family Ysc84 PF04366.12 OAJ20603.1 - 3.8e-37 126.9 0.6 8.6e-37 125.8 0.6 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_9 PF14604.6 OAJ20603.1 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ20603.1 - 2.8e-12 46.0 0.0 4.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ20603.1 - 1.2e-09 37.7 0.0 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AA_permease_2 PF13520.6 OAJ20604.1 - 6.5e-53 180.1 34.5 1.3e-52 179.1 34.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ20604.1 - 7.8e-13 47.8 27.6 7.8e-13 47.8 27.6 1.7 2 0 0 2 2 2 1 Amino acid permease Pterin_bind PF00809.22 OAJ20605.1 - 3.9e-56 190.5 4.1 4.8e-50 170.5 0.6 3.0 2 1 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 OAJ20605.1 - 1.2e-28 99.9 0.0 2.4e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 OAJ20605.1 - 9.1e-24 84.2 0.0 2.5e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase Tfb5 PF06331.12 OAJ20606.1 - 1.2e-25 89.3 0.1 1.3e-25 89.2 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 HTH_53 PF18606.1 OAJ20606.1 - 0.062 13.0 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain RRM_1 PF00076.22 OAJ20607.1 - 4.1e-06 26.5 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N2227 PF07942.12 OAJ20607.1 - 1.2 8.2 3.8 0.78 8.9 0.0 2.0 2 0 0 2 2 2 0 N2227-like protein BTB PF00651.31 OAJ20608.1 - 6.8e-15 55.3 0.2 5.3e-10 39.5 0.0 3.6 3 0 0 3 3 3 2 BTB/POZ domain CAP_GLY PF01302.25 OAJ20608.1 - 3e-07 30.3 0.6 1.4e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 CAP-Gly domain 6PGD PF00393.19 OAJ20608.1 - 2 7.7 6.9 15 4.9 5.7 2.4 2 0 0 2 2 2 0 6-phosphogluconate dehydrogenase, C-terminal domain Pkinase PF00069.25 OAJ20609.1 - 1.2e-75 254.3 0.0 1.6e-75 253.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20609.1 - 9.7e-42 143.0 0.0 1.8e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OAJ20609.1 - 6.1e-20 71.2 0.0 5.7e-09 36.0 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 OAJ20609.1 - 2.6e-08 33.5 0.0 6e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ20609.1 - 0.0019 17.1 0.0 0.0039 16.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ20609.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ20609.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SF3A2 PF16835.5 OAJ20610.1 - 6.3e-29 100.2 0.0 1e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAJ20610.1 - 1.5e-06 28.4 0.7 3.1e-06 27.4 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Glyco_transf_20 PF00982.21 OAJ20611.1 - 1.3e-140 469.3 0.0 9.3e-130 433.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ20611.1 - 4.2e-74 248.6 0.0 7e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAJ20611.1 - 8.4e-05 22.4 0.0 0.016 15.0 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAJ20611.1 - 0.0014 18.2 0.6 0.0072 15.9 0.0 2.2 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase ATP_transf PF09830.9 OAJ20612.1 - 1.9e-14 53.5 0.0 3.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 OAJ20612.1 - 0.04 14.6 0.0 0.24 12.1 0.1 2.3 2 1 0 2 2 2 0 HIT domain Pyr_redox_2 PF07992.14 OAJ20613.1 - 0.00016 21.0 0.0 0.00091 18.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Aminotran_3 PF00202.21 OAJ20614.1 - 8.7e-88 294.7 0.0 1.6e-87 293.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III SUZ PF12752.7 OAJ20615.1 - 1.5e-09 38.5 21.8 1.5e-09 38.5 21.8 9.1 11 3 0 11 11 11 1 SUZ domain R3H PF01424.22 OAJ20615.1 - 3.7e-07 30.0 0.0 6.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 R3H domain Adaptin_N PF01602.20 OAJ20616.1 - 1.7e-99 333.8 10.7 2.8e-99 333.0 10.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OAJ20616.1 - 2e-61 205.6 0.0 6e-61 204.1 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OAJ20616.1 - 2.4e-59 199.2 0.2 6.1e-59 197.9 0.2 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 OAJ20616.1 - 3.3e-12 46.7 10.8 7.9e-09 35.8 0.1 4.2 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ20616.1 - 6.7e-10 39.2 6.7 0.011 16.1 0.0 5.7 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OAJ20616.1 - 4.7e-07 29.5 0.1 0.037 14.3 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 OAJ20616.1 - 0.00063 19.9 0.3 0.012 15.8 0.0 3.0 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform ParcG PF10274.9 OAJ20616.1 - 0.016 15.3 0.7 0.84 9.7 0.0 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein HEAT_EZ PF13513.6 OAJ20616.1 - 0.032 14.7 0.7 6.6 7.4 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF5071 PF16804.5 OAJ20616.1 - 0.064 13.5 1.0 7.9 6.8 0.0 4.2 2 1 1 4 4 4 0 Domain of unknown function (DUF5071) Arm PF00514.23 OAJ20616.1 - 0.092 12.8 0.3 1.7e+02 2.4 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DAO PF01266.24 OAJ20617.1 - 6e-54 184.0 2.7 6.9e-54 183.8 2.7 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ20617.1 - 1.8e-06 28.4 0.1 0.12 13.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ20617.1 - 7.4e-06 25.4 0.1 0.057 12.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ20617.1 - 0.00017 21.8 0.3 0.00043 20.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 OAJ20617.1 - 0.0032 16.4 0.5 1 8.1 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Mqo PF06039.15 OAJ20617.1 - 0.0034 16.0 0.0 0.43 9.1 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 OAJ20617.1 - 0.0091 15.3 0.2 0.88 8.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 OAJ20617.1 - 0.019 14.2 0.1 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 OAJ20617.1 - 0.031 13.6 0.1 0.83 9.0 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 OAJ20617.1 - 0.039 13.9 0.6 0.36 10.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAJ20617.1 - 0.043 13.1 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 OAJ20617.1 - 0.044 12.9 0.1 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) MCRA PF06100.11 OAJ20617.1 - 0.096 11.5 0.6 0.43 9.3 0.5 1.8 2 0 0 2 2 2 0 MCRA family Biotin_lipoyl_2 PF13533.6 OAJ20617.1 - 0.14 12.0 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like UCH PF00443.29 OAJ20619.1 - 2e-39 135.6 0.0 3.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ20619.1 - 6.2e-05 22.7 0.0 0.0073 15.9 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Sel1 PF08238.12 OAJ20620.1 - 8.8e-40 134.3 26.2 3.3e-06 27.6 0.2 8.3 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 OAJ20620.1 - 0.9 10.3 5.5 4 8.3 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Velvet PF11754.8 OAJ20621.1 - 4.7e-11 43.1 0.0 4.7e-11 43.1 0.0 3.7 2 2 1 3 3 3 2 Velvet factor zf-UBR PF02207.20 OAJ20622.1 - 6.9e-12 45.4 10.1 6.9e-12 45.4 10.1 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 OAJ20622.1 - 0.00044 20.1 3.9 0.00044 20.1 3.9 3.8 4 0 0 4 4 4 1 PHD-finger TP6A_N PF04406.14 OAJ20623.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SF3A2 PF16835.5 OAJ20626.1 - 7e-29 100.1 0.0 1.2e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAJ20626.1 - 1.5e-06 28.3 0.7 3.2e-06 27.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Peptidase_S9 PF00326.21 OAJ20627.1 - 6.3e-50 169.6 0.1 9.8e-50 169.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAJ20627.1 - 0.0011 18.5 0.1 0.002 17.6 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase PD40 PF07676.12 OAJ20627.1 - 0.0016 18.3 1.0 0.0083 16.0 0.1 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Esterase PF00756.20 OAJ20627.1 - 0.0032 17.1 0.8 0.0074 16.0 0.8 1.5 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 OAJ20627.1 - 0.014 14.3 0.3 0.03 13.2 0.3 1.4 1 0 0 1 1 1 0 Carboxylesterase family AXE1 PF05448.12 OAJ20627.1 - 0.034 12.8 2.0 2.9 6.5 2.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OAJ20627.1 - 0.069 12.8 1.2 1.7 8.3 0.4 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Arylesterase PF01731.20 OAJ20628.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Arylesterase Dabb PF07876.12 OAJ20629.1 - 1e-15 58.1 0.1 1.2e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Clathrin_H_link PF13838.6 OAJ20646.1 - 0.095 12.6 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Clathrin-H-link Ribosomal_L37e PF01907.19 OAJ20646.1 - 1 9.6 9.0 2 8.7 9.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e PolC_DP2 PF03833.13 OAJ20646.1 - 3.7 5.3 4.2 4.8 4.9 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DSPn PF14671.6 OAJ20647.1 - 4.6e-33 114.7 0.0 6.1e-32 111.0 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAJ20647.1 - 2.9e-13 49.8 0.0 5.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ20647.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PV-1 PF06637.11 OAJ20647.1 - 0.019 13.8 1.6 0.029 13.2 1.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PTPlike_phytase PF14566.6 OAJ20647.1 - 0.033 14.3 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF5320 PF17253.2 OAJ20647.1 - 0.04 15.0 0.2 0.42 11.7 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) COG2 PF06148.11 OAJ20647.1 - 0.15 12.2 1.4 0.28 11.3 1.4 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 OAJ20647.1 - 0.19 11.1 3.1 0.32 10.3 3.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2968 PF11180.8 OAJ20647.1 - 3.4 7.3 8.7 1.4 8.5 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DUF4692 PF15763.5 OAJ20647.1 - 8.1 6.9 11.3 29 5.1 11.3 1.9 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) SHNi-TPR PF10516.9 OAJ20648.1 - 4.8e-06 25.9 1.7 3e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 OAJ20648.1 - 0.004 17.2 4.8 0.13 12.4 1.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ20648.1 - 0.0078 16.5 4.2 5.5 7.4 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ20648.1 - 0.017 14.9 1.6 1.6 8.6 0.7 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ20648.1 - 0.21 11.8 2.2 4.5 7.5 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ20648.1 - 0.3 11.0 2.0 8.5 6.4 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3464 PF11947.8 OAJ20648.1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.4 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 DNA_pol_phi PF04931.13 OAJ20648.1 - 0.87 7.6 12.4 0.94 7.5 1.4 2.3 2 0 0 2 2 2 0 DNA polymerase phi HGTP_anticodon2 PF12745.7 OAJ20648.1 - 1.2 8.5 6.1 6 6.3 0.4 2.4 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs AATF-Che1 PF13339.6 OAJ20648.1 - 1.9 9.2 10.8 2.5 8.8 0.8 3.6 3 2 0 3 3 3 0 Apoptosis antagonizing transcription factor Tubulin PF00091.25 OAJ20649.1 - 1.6e-68 230.8 0.0 2.2e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ20649.1 - 6.5e-41 139.4 0.0 1.2e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ20649.1 - 0.00087 19.6 0.0 0.0023 18.2 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ20649.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain Abhydrolase_1 PF00561.20 OAJ20650.1 - 4.4e-21 75.7 0.0 1.3e-20 74.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ20650.1 - 5.5e-17 63.1 0.0 6.8e-16 59.5 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ20650.1 - 6e-15 55.2 0.0 4.3e-13 49.1 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAJ20650.1 - 4.3e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 OAJ20650.1 - 8.6e-05 22.6 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAJ20650.1 - 0.00016 21.6 0.0 0.00051 20.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 OAJ20650.1 - 0.00039 20.1 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 OAJ20650.1 - 0.00087 18.9 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 OAJ20650.1 - 0.0011 17.8 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.16 OAJ20650.1 - 0.0025 17.7 0.0 1.2 8.9 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF915 PF06028.11 OAJ20650.1 - 0.0066 15.8 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 OAJ20650.1 - 0.072 13.2 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.25 OAJ20650.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.11 OAJ20650.1 - 0.096 11.7 0.0 0.61 9.0 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.21 OAJ20650.1 - 0.1 12.0 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 OAJ20650.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 OAJ20650.1 - 0.11 11.3 0.0 0.36 9.7 0.0 1.8 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF676 PF05057.14 OAJ20650.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 OAJ20650.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C3HC4_3 PF13920.6 OAJ20651.1 - 2.8e-07 30.3 7.3 2.8e-07 30.3 7.3 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF971 PF06155.12 OAJ20651.1 - 0.29 11.8 0.0 0.29 11.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF971) zf-C2H2 PF00096.26 OAJ20651.1 - 1.8 9.2 26.1 0.15 12.5 0.6 5.2 6 0 0 6 6 6 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 OAJ20651.1 - 3.6 7.5 10.0 1.5 8.8 6.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 JmjC PF02373.22 OAJ20652.1 - 5.3e-40 136.4 0.1 1e-39 135.5 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ20652.1 - 3.9e-12 45.9 0.1 8.7e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 OAJ20652.1 - 6.2e-10 39.2 2.8 3.6e-08 33.5 1.7 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAJ20652.1 - 6.8e-10 39.1 3.4 2.2e-09 37.5 1.5 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD PF00628.29 OAJ20652.1 - 4.4 7.3 5.5 13 5.8 5.5 1.8 1 0 0 1 1 1 0 PHD-finger IDO PF01231.18 OAJ20653.1 - 1.1e-122 410.0 0.0 3e-122 408.5 0.0 1.7 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase PAXX PF15384.6 OAJ20653.1 - 0.18 11.5 1.3 18 5.0 0.0 3.2 2 1 1 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DEAD PF00270.29 OAJ20654.1 - 6.4e-43 146.5 0.7 1.1e-42 145.8 0.7 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20654.1 - 8.2e-32 109.9 0.1 8.1e-31 106.7 0.0 2.5 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20654.1 - 4.3e-06 26.8 0.0 7.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ20654.1 - 0.00011 22.5 0.3 0.0021 18.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ20654.1 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 OAJ20654.1 - 0.046 13.0 0.1 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 OAJ20654.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 OAJ20654.1 - 0.067 12.5 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.21 OAJ20654.1 - 0.069 12.7 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 OAJ20654.1 - 0.12 12.6 0.2 0.36 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain fragilysinNterm PF16376.5 OAJ20654.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of fragilysin Not1 PF04054.15 OAJ20655.1 - 4e-120 401.1 0.0 1.1e-119 399.7 0.0 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAJ20655.1 - 2.2e-96 321.6 0.2 3.9e-95 317.5 0.4 2.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAJ20655.1 - 4.7e-58 195.3 3.6 1.1e-57 194.1 3.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAJ20655.1 - 8e-54 181.7 0.0 1.8e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAJ20655.1 - 1.7e-46 158.0 2.8 5.5e-46 156.4 2.8 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Usp PF00582.26 OAJ20656.1 - 2.3e-20 73.5 1.1 1.1e-19 71.4 0.1 2.6 2 0 0 2 2 2 1 Universal stress protein family Sld5 PF05916.11 OAJ20657.1 - 2.3e-21 76.3 0.1 3.3e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein R3H PF01424.22 OAJ20659.1 - 9.8e-14 51.1 0.1 2.1e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 R3H domain HELP PF03451.14 OAJ20659.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 HELP motif Nsp1 PF11501.8 OAJ20659.1 - 0.18 11.9 0.0 17 5.5 0.0 2.4 1 1 1 2 2 2 0 Non structural protein Nsp1 RhoGAP PF00620.27 OAJ20660.1 - 9e-38 129.5 0.0 2.1e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 OAJ20660.1 - 8.2e-16 58.7 0.0 7.5e-13 49.1 0.0 2.7 2 1 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 OAJ20660.1 - 1.5e-09 38.0 0.0 3.9e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.6 OAJ20660.1 - 8.5e-05 22.9 0.0 0.00025 21.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ20660.1 - 0.00049 20.6 0.0 0.063 13.8 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 OAJ20660.1 - 0.088 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DER1 PF04511.15 OAJ20661.1 - 5.5e-46 156.9 2.5 6.6e-46 156.7 2.5 1.1 1 0 0 1 1 1 1 Der1-like family CitMHS PF03600.16 OAJ20661.1 - 0.019 14.2 0.4 0.023 13.9 0.4 1.2 1 0 0 1 1 1 0 Citrate transporter Trypan_PARP PF05887.11 OAJ20663.1 - 0.00037 20.5 95.5 0.00053 20.0 43.9 3.8 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) Gp-FAR-1 PF05823.12 OAJ20663.1 - 0.013 15.9 0.3 3.6 7.9 0.0 3.2 3 0 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF2603 PF10788.9 OAJ20663.1 - 0.17 11.9 0.1 83 3.2 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2603) Pyridox_ox_2 PF12900.7 OAJ20664.1 - 1.3e-36 125.7 0.0 1.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNA_pol_3_Rpc31 PF11705.8 OAJ20665.1 - 0.014 15.6 7.4 0.017 15.4 7.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ20665.1 - 0.14 10.3 7.6 0.16 10.2 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ20665.1 - 0.19 11.1 5.3 0.22 10.9 5.3 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OAJ20665.1 - 0.36 10.4 5.7 0.46 10.0 5.7 1.2 1 0 0 1 1 1 0 PPP4R2 DUF4698 PF15769.5 OAJ20665.1 - 1.8 7.5 3.8 0.89 8.5 2.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4698) Astro_capsid_p PF12226.8 OAJ20665.1 - 2.7 7.1 9.7 3.6 6.6 9.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SEEEED PF14797.6 OAJ20665.1 - 8 6.6 21.4 8.9 6.5 14.1 2.2 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Spt20 PF12090.8 OAJ20666.1 - 0.62 9.6 11.3 1.3 8.6 11.3 1.5 1 0 0 1 1 1 0 Spt20 family DRMBL PF07522.14 OAJ20667.1 - 0.09 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Rhomboid_N PF12122.8 OAJ20667.1 - 0.13 12.5 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease CARD PF00619.21 OAJ20667.1 - 0.22 11.6 0.7 0.48 10.5 0.7 1.5 1 0 0 1 1 1 0 Caspase recruitment domain SDP_N PF12278.8 OAJ20667.1 - 7.6 6.7 8.8 0.16 12.1 1.0 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal Ribosomal_L7Ae PF01248.26 OAJ20668.1 - 6.1e-26 90.0 0.1 7.8e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAJ20668.1 - 0.0009 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OAJ20668.1 - 0.004 17.2 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Paf67 PF10255.9 OAJ20669.1 - 2.6e-167 556.9 0.0 4e-167 556.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAJ20669.1 - 0.0007 19.5 0.4 0.0063 16.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ20669.1 - 0.0072 16.1 0.0 0.067 13.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HOOK PF05622.12 OAJ20670.1 - 2e-52 178.3 58.8 2e-52 178.3 58.8 3.5 1 1 2 3 3 3 2 HOOK protein BLOC1_2 PF10046.9 OAJ20670.1 - 0.0011 19.2 10.0 0.0011 19.2 10.0 6.2 4 2 1 6 6 6 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_N PF15905.5 OAJ20670.1 - 0.0045 16.5 6.0 0.0045 16.5 6.0 6.2 2 2 4 6 6 6 3 Hyaluronan mediated motility receptor N-terminal Laminin_II PF06009.12 OAJ20670.1 - 0.0046 17.0 13.2 0.0046 17.0 13.2 6.2 4 1 2 7 7 7 3 Laminin Domain II Filament PF00038.21 OAJ20670.1 - 0.44 10.1 83.8 0.046 13.3 12.6 4.7 2 2 2 4 4 4 0 Intermediate filament protein DUF743 PF05332.11 OAJ20670.1 - 1.7 8.7 14.3 0.091 12.8 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF743) Cellulase PF00150.18 OAJ20671.1 - 3.4e-14 52.9 7.0 1.1e-13 51.2 7.0 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 OAJ20672.1 - 1.6e-07 31.3 9.5 3.4e-07 30.3 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-SNARE_C PF12352.8 OAJ20673.1 - 9.1e-14 51.5 0.6 1.9e-13 50.5 0.3 1.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ20673.1 - 1.8e-06 27.7 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Docking PF08990.11 OAJ20674.1 - 0.27 10.9 3.9 0.67 9.6 3.9 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking ERM PF00769.19 OAJ20674.1 - 0.3 10.9 10.3 0.032 14.1 6.0 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family zf-CCHC PF00098.23 OAJ20691.1 - 0.00012 21.9 0.8 0.00021 21.2 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF5473 PF17567.2 OAJ20691.1 - 0.16 12.3 2.4 1.9 8.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5473) Pkinase PF00069.25 OAJ20692.1 - 4.2e-47 160.7 0.0 6.4e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ20692.1 - 8.3e-25 87.5 0.0 1.5e-24 86.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ20692.1 - 8.6e-06 25.3 0.0 2.5e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OAJ20692.1 - 0.013 14.5 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CLPTM1 PF05602.12 OAJ20693.1 - 7.7e-100 334.9 0.0 9.2e-97 324.8 0.0 2.7 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OAJ20693.1 - 5.5e-11 42.1 1.0 2e-08 33.9 0.4 2.5 2 0 0 2 2 2 2 PQ loop repeat Carboxyl_trans PF01039.22 OAJ20694.1 - 7.1e-133 443.8 0.0 8.7e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 OAJ20694.1 - 0.011 15.0 1.4 0.028 13.7 0.1 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ACCA PF03255.14 OAJ20694.1 - 0.021 14.7 0.0 4.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MdcE PF06833.11 OAJ20694.1 - 0.029 13.9 0.3 0.49 9.8 0.1 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) RVT_1 PF00078.27 OAJ20695.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2235 PF09994.9 OAJ20697.1 - 8.6e-70 235.3 0.0 1.6e-69 234.4 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.16 OAJ20698.1 - 2.1e-26 93.3 0.0 3.1e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.18 OAJ20700.1 - 1.4e-06 28.3 9.7 2.5e-06 27.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LBP_BPI_CETP PF01273.25 OAJ20702.1 - 0.31 10.6 7.2 0.47 10.0 7.2 1.4 1 1 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain DUF1943 PF09172.11 OAJ20702.1 - 2.2 7.4 7.4 2.4 7.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Peptidase_A21 PF03566.13 OAJ20702.1 - 3.5 5.8 15.2 3.8 5.7 15.2 1.0 1 0 0 1 1 1 0 Peptidase family A21 PBD PF00786.28 OAJ20705.1 - 0.00053 20.3 0.0 0.0017 18.7 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Nitroreductase PF00881.24 OAJ20709.1 - 2.1e-10 40.9 0.0 2.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DNA_pol3_tau_5 PF12170.8 OAJ20709.1 - 0.11 12.5 0.5 0.18 11.8 0.5 1.3 1 0 0 1 1 1 0 DNA polymerase III tau subunit V interacting with alpha zf-MYND PF01753.18 OAJ20710.1 - 2.3e-07 30.8 14.2 7.1e-07 29.2 14.2 1.9 1 0 0 1 1 1 1 MYND finger DUF702 PF05142.12 OAJ20711.1 - 0.26 11.8 6.5 2 8.9 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) NAD_binding_8 PF13450.6 OAJ20712.1 - 3.5e-08 33.6 0.0 9.3e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ20712.1 - 0.033 13.4 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ20712.1 - 0.05 13.2 0.7 0.076 12.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ20712.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 OAJ20712.1 - 0.11 13.0 0.2 46 4.7 0.0 3.0 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ20712.1 - 0.19 10.8 0.5 0.35 9.9 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Terpene_synth_C PF03936.16 OAJ20712.1 - 0.52 9.6 5.9 0.044 13.1 1.2 1.5 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Mito_carr PF00153.27 OAJ20713.1 - 5.4e-65 215.4 2.9 2.9e-21 75.2 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PDCD2_C PF04194.13 OAJ20715.1 - 1.2e-31 110.1 6.5 2.4e-31 109.1 1.8 3.1 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain BSP_II PF05432.11 OAJ20715.1 - 1.7 8.3 13.6 0.74 9.4 5.2 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 OAJ20715.1 - 1.9 8.1 30.5 1.3 8.6 13.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glutaredoxin PF00462.24 OAJ20716.1 - 4.8e-18 65.1 0.0 9.1e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Met_10 PF02475.16 OAJ20717.1 - 4.6e-52 176.7 0.0 1.2e-41 142.7 0.0 2.5 2 1 0 2 2 2 2 Met-10+ like-protein p450 PF00067.22 OAJ20718.1 - 3.9e-55 187.4 0.0 4.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HsbA PF12296.8 OAJ20720.1 - 7.3e-06 26.4 2.7 1.8e-05 25.1 2.7 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A TatD_DNase PF01026.21 OAJ20722.1 - 1.7e-19 70.2 0.3 4.4e-19 68.9 0.3 1.6 1 1 0 1 1 1 1 TatD related DNase TruB_N PF01509.18 OAJ20723.1 - 9e-36 123.5 0.0 2.1e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ20723.1 - 8.4e-06 25.9 0.2 1.6e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 OAJ20723.1 - 0.13 12.3 0.0 0.69 10.0 0.1 2.1 2 0 0 2 2 2 0 DKCLD (NUC011) domain Glyco_hydro_17 PF00332.18 OAJ20724.1 - 7.7e-09 35.6 0.3 7.8e-05 22.4 0.2 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF2528 PF10800.8 OAJ20725.1 - 0.11 13.1 0.9 3.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) DUF5516 PF17637.2 OAJ20727.1 - 0.13 12.1 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5516) DUF4089 PF13318.6 OAJ20727.1 - 0.63 10.5 4.2 20 5.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4089) zf-HIT PF04438.16 OAJ20728.1 - 5.3e-08 32.6 10.7 8e-08 32.0 10.7 1.3 1 0 0 1 1 1 1 HIT zinc finger DCP2 PF05026.13 OAJ20729.1 - 1.7e-23 82.8 0.0 3.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAJ20729.1 - 3.3e-16 59.5 0.0 6.3e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF2012 PF09430.10 OAJ20730.1 - 1.8e-21 76.5 0.0 3.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) 2_5_RNA_ligase2 PF13563.6 OAJ20731.1 - 1.3e-17 64.1 2.0 1.1e-16 61.0 0.4 2.4 2 1 0 2 2 2 1 2'-5' RNA ligase superfamily Cnd1 PF12717.7 OAJ20732.1 - 8.2e-53 178.8 5.4 7.6e-47 159.4 0.1 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 OAJ20732.1 - 7.5e-40 136.5 0.0 7.5e-40 136.5 0.0 3.8 5 0 0 5 5 3 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 OAJ20732.1 - 4.5e-07 28.8 2.3 0.022 13.4 0.1 4.5 4 2 1 5 5 5 2 Adaptin N terminal region HEAT PF02985.22 OAJ20732.1 - 5.7e-07 29.3 0.9 0.81 10.1 0.0 6.1 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 OAJ20732.1 - 2.5e-06 27.8 1.0 0.25 11.7 0.0 4.5 6 0 0 6 6 5 2 HEAT repeats RTP1_C1 PF10363.9 OAJ20732.1 - 0.0001 22.5 0.4 0.44 10.7 0.1 4.1 2 2 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 OAJ20732.1 - 0.00023 20.5 6.0 0.00023 20.4 0.5 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain CDC45 PF02724.14 OAJ20732.1 - 0.029 12.7 15.1 0.064 11.5 15.1 1.5 1 0 0 1 1 1 0 CDC45-like protein HEAT_EZ PF13513.6 OAJ20732.1 - 0.073 13.6 7.0 1.8 9.1 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat PqqD PF05402.12 OAJ20732.1 - 0.44 10.9 2.1 23 5.4 0.0 4.6 7 0 0 7 7 7 0 Coenzyme PQQ synthesis protein D (PqqD) SBF2 PF12335.8 OAJ20732.1 - 0.66 9.5 4.4 1.3 8.6 4.4 1.6 1 0 0 1 1 1 0 Myotubularin protein ORC5_C PF14630.6 OAJ20733.1 - 5.6e-52 177.0 0.1 1.2e-51 175.9 0.1 1.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAJ20733.1 - 0.0018 18.7 0.2 0.014 15.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Thioesterase PF00975.20 OAJ20735.1 - 5.2e-09 36.6 0.0 8.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Iwr1 PF08574.10 OAJ20736.1 - 0.0015 19.5 17.8 0.0015 19.5 17.8 4.0 3 1 0 3 3 3 1 Transcription factor Iwr1 PIF1 PF05970.14 OAJ20753.1 - 3.7e-60 204.0 1.0 1.1e-57 195.9 1.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ20753.1 - 1e-20 74.3 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ20753.1 - 2.5e-11 44.1 0.1 5.3e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ20753.1 - 6.1e-05 22.6 0.3 0.00029 20.4 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 OAJ20753.1 - 8.5e-05 22.8 0.2 0.00032 21.0 0.2 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ20753.1 - 0.00062 19.6 0.2 0.68 9.6 0.2 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAJ20753.1 - 0.00073 19.3 0.3 0.0063 16.3 0.2 2.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 OAJ20753.1 - 0.0032 16.6 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 OAJ20753.1 - 0.005 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 OAJ20753.1 - 0.012 14.9 0.0 0.031 13.5 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAJ20753.1 - 0.012 16.0 0.1 0.034 14.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 OAJ20753.1 - 0.013 14.5 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 OAJ20753.1 - 0.016 15.0 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 OAJ20753.1 - 0.021 14.3 0.0 0.055 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OAJ20753.1 - 0.028 14.1 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 OAJ20753.1 - 0.031 14.2 0.2 0.14 12.0 0.2 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SH3_13 PF18335.1 OAJ20753.1 - 0.032 14.1 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 OAJ20753.1 - 0.034 14.1 0.1 0.085 12.8 0.1 1.8 1 1 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 OAJ20753.1 - 0.037 13.2 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Herpes_Helicase PF02689.14 OAJ20753.1 - 0.057 11.3 0.3 0.48 8.3 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_14 PF13173.6 OAJ20753.1 - 0.089 12.8 0.0 0.54 10.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain HTH_17 PF12728.7 OAJ20753.1 - 0.097 12.9 0.1 16 5.7 0.0 2.8 3 0 0 3 3 2 0 Helix-turn-helix domain RsgA_GTPase PF03193.16 OAJ20753.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OAJ20753.1 - 0.11 12.5 0.2 0.9 9.5 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 OAJ20753.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RHH_1 PF01402.21 OAJ20753.1 - 0.47 10.5 1.7 3 7.9 0.2 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family DUF2420 PF10336.9 OAJ20754.1 - 8e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) E1-E2_ATPase PF00122.20 OAJ20755.1 - 1.7e-26 92.8 0.0 4.9e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 OAJ20755.1 - 1e-25 90.2 0.0 1.9e-24 86.1 0.0 2.4 1 1 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 OAJ20755.1 - 6.8e-17 62.5 0.1 1.1e-06 29.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OAJ20755.1 - 1.2e-05 25.1 9.2 3e-05 23.8 9.2 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAJ20755.1 - 8e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ20755.1 - 0.007 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus NAD_kinase PF01513.21 OAJ20756.1 - 6.7e-53 179.8 0.0 8.7e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MFAP1 PF06991.11 OAJ20757.1 - 2e-63 214.2 22.7 2e-63 214.2 22.7 3.0 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 OAJ20757.1 - 0.13 12.4 0.7 0.36 11.0 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle AMP-binding PF00501.28 OAJ20758.1 - 2.7e-68 230.5 0.0 3.3e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ20758.1 - 0.0005 21.0 0.1 0.0013 19.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.9 OAJ20758.1 - 0.067 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 RCC1 PF00415.18 OAJ20759.1 - 2.8e-14 53.4 4.8 0.025 15.2 0.0 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAJ20759.1 - 1.3e-10 41.5 0.0 5.8e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank_5 PF13857.6 OAJ20759.1 - 1.5e-09 37.9 0.1 3.4e-07 30.4 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ20759.1 - 1.9e-07 31.5 0.3 0.00018 22.0 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ20759.1 - 6.8e-06 26.6 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ20759.1 - 6.9e-06 26.0 1.0 0.14 12.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat RCC1_2 PF13540.6 OAJ20759.1 - 0.00085 19.1 19.0 0.0017 18.1 0.0 5.7 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.30 OAJ20759.1 - 0.0073 16.7 4.0 0.64 10.6 0.2 3.5 3 0 0 3 3 3 1 Ankyrin repeat THF_DHG_CYH PF00763.23 OAJ20760.1 - 3.2e-24 85.4 0.1 8.9e-24 84.0 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAJ20760.1 - 2.5e-13 49.6 0.2 6.2e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IMPa_N_2 PF18650.1 OAJ20760.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Sortilin-Vps10 PF15902.5 OAJ20762.1 - 2.2e-137 458.5 0.0 2.8e-137 458.2 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAJ20762.1 - 7.6e-41 140.3 1.5 7.6e-41 140.3 1.5 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal CHB_HEX_C PF03174.13 OAJ20762.1 - 2.8e-05 24.0 1.2 2.4 8.2 0.0 3.6 3 0 0 3 3 3 3 Chitobiase/beta-hexosaminidase C-terminal domain BNR PF02012.20 OAJ20762.1 - 0.0011 18.6 23.1 1.4 9.2 1.7 6.8 6 0 0 6 6 6 4 BNR/Asp-box repeat F5_F8_type_C PF00754.25 OAJ20762.1 - 0.02 15.0 4.4 16 5.7 0.0 5.4 5 1 1 6 6 6 0 F5/8 type C domain IKI3 PF04762.12 OAJ20763.1 - 4.8e-232 772.8 0.0 7.8e-232 772.1 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.8 OAJ20763.1 - 5.1e-05 23.4 4.4 0.00067 19.8 0.5 3.1 2 0 0 2 2 2 1 Selenocysteine synthase N terminal TPR_2 PF07719.17 OAJ20763.1 - 0.03 14.4 1.5 0.29 11.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 OAJ20763.1 - 0.044 13.7 0.5 0.28 11.0 0.1 2.6 2 1 1 3 3 3 0 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OAJ20763.1 - 0.085 13.2 0.1 16 5.9 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AATF-Che1 PF13339.6 OAJ20763.1 - 0.13 12.9 4.8 0.34 11.6 4.8 1.7 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor MFS_1 PF07690.16 OAJ20764.1 - 1.3e-32 113.1 41.8 6.1e-31 107.6 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PIEZO PF15917.5 OAJ20764.1 - 0.075 12.5 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Piezo LapA_dom PF06305.11 OAJ20764.1 - 0.3 10.9 4.1 0.94 9.3 0.2 3.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Pmp3 PF01679.17 OAJ20767.1 - 3e-22 78.6 9.5 4.1e-22 78.1 9.5 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator WD40_4 PF16300.5 OAJ20768.1 - 6.6e-20 70.7 8.4 1.7e-14 53.4 0.0 3.3 3 0 0 3 3 3 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 OAJ20768.1 - 0.00086 19.6 0.3 2.2 8.7 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ20768.1 - 0.045 14.6 0.1 2.6 9.1 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat MBOAT PF03062.19 OAJ20769.1 - 7.1e-38 130.8 14.0 7.1e-38 130.8 14.0 2.8 2 2 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Sec10 PF07393.11 OAJ20770.1 - 0.056 11.9 0.2 0.068 11.6 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Sigma70_ner PF04546.13 OAJ20770.1 - 0.19 11.6 0.1 0.25 11.2 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FA_desaturase PF00487.24 OAJ20773.1 - 8.4e-23 81.5 19.2 1.3e-22 80.9 16.6 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 OAJ20773.1 - 4.5e-17 61.3 0.1 7.8e-17 60.5 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) WD40 PF00400.32 OAJ20774.1 - 5.7e-12 46.0 3.4 0.18 12.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat RRM_1 PF00076.22 OAJ20775.1 - 4.5e-19 68.0 0.0 8.2e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ20775.1 - 1.3e-07 31.6 0.0 2.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 OAJ20775.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ20775.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.14 OAJ20775.1 - 0.88 7.8 13.7 1.2 7.4 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAJ20775.1 - 1.3 7.7 3.5 1.7 7.3 3.5 1.2 1 0 0 1 1 1 0 Presenilin Mpv17_PMP22 PF04117.12 OAJ20776.1 - 1.8e-05 24.9 1.7 7e-05 23.0 1.5 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 OAJ20776.1 - 0.011 16.0 1.2 5.2 7.4 0.1 3.2 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain GPI-anchored PF10342.9 OAJ20777.1 - 0.035 14.9 0.0 0.07 13.9 0.0 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tim17 PF02466.19 OAJ20778.1 - 6.4e-36 123.1 5.3 8e-36 122.8 5.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.12 OAJ20778.1 - 6.1 6.9 7.0 8.3 6.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF543) CoA_transf_3 PF02515.17 OAJ20779.1 - 1.1e-58 199.1 0.0 1.9e-58 198.3 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III Sec1 PF00995.23 OAJ20780.1 - 2.9e-88 297.5 0.0 4.8e-88 296.8 0.0 1.3 1 1 0 1 1 1 1 Sec1 family PTPLA PF04387.14 OAJ20781.1 - 1.4e-51 174.5 7.5 2.6e-51 173.6 7.5 1.5 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L27A PF00828.19 OAJ20782.1 - 6.8e-35 120.5 0.0 9.4e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A BCDHK_Adom3 PF10436.9 OAJ20783.1 - 4.9e-63 211.8 0.0 6.8e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ20783.1 - 2.5e-13 50.5 0.0 4.3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ20783.1 - 8.1e-05 22.5 0.0 0.00017 21.4 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutS_III PF05192.18 OAJ20783.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 MutS domain III PT PF04886.12 OAJ20784.1 - 0.0096 15.4 7.5 0.0096 15.4 7.5 2.7 2 0 0 2 2 2 1 PT repeat Bestrophin PF01062.21 OAJ20785.1 - 1.1e-33 116.9 0.2 1.6e-33 116.4 0.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Collagen_mid PF15984.5 OAJ20786.1 - 0.0047 16.7 1.3 0.0047 16.7 1.3 2.8 1 1 2 3 3 3 1 Bacterial collagen, middle region PNTB_4TM PF12769.7 OAJ20786.1 - 0.2 12.1 3.6 0.25 11.8 1.7 2.1 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch UCH PF00443.29 OAJ20787.1 - 3.4e-63 213.5 0.0 5e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ20787.1 - 3.4e-18 66.3 0.0 5.8e-15 55.7 0.0 2.3 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 OAJ20787.1 - 1.4e-09 38.1 1.0 2.9e-09 37.1 1.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 OAJ20787.1 - 0.0082 16.7 0.0 0.09 13.3 0.0 2.5 1 1 0 1 1 1 1 Rhodanese-like domain DUF104 PF01954.16 OAJ20787.1 - 0.055 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 Yip1 PF04893.17 OAJ20788.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain TssO PF17561.2 OAJ20788.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO ATP_Ca_trans_C PF12424.8 OAJ20788.1 - 0.17 12.4 0.3 0.43 11.1 0.3 1.6 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal PKcGMP_CC PF16808.5 OAJ20805.1 - 9.2e-06 25.4 2.8 9.2e-06 25.4 2.8 2.1 2 1 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 OAJ20805.1 - 0.00048 20.4 13.7 0.00062 20.1 13.7 1.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Sec66 PF09802.9 OAJ20805.1 - 0.0055 16.3 1.8 0.0078 15.8 1.8 1.2 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 AAA_13 PF13166.6 OAJ20805.1 - 0.036 12.7 4.4 0.05 12.3 4.4 1.1 1 0 0 1 1 1 0 AAA domain BSD PF03909.17 OAJ20805.1 - 0.1 12.6 0.4 0.33 11.0 0.2 2.0 1 1 0 2 2 2 0 BSD domain Spc7 PF08317.11 OAJ20805.1 - 0.24 10.2 10.3 0.32 9.8 10.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 OAJ20805.1 - 0.27 11.1 8.6 0.42 10.4 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HIP1_clath_bdg PF16515.5 OAJ20805.1 - 0.32 11.6 15.5 0.057 14.0 12.0 1.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 OAJ20805.1 - 1.3 9.4 10.5 2.7 8.4 10.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IHO1 PF15771.5 OAJ20805.1 - 1.3 7.7 11.1 1.3 7.8 6.4 2.0 1 1 1 2 2 2 0 Interactor of HORMAD1 protein 1 TMPIT PF07851.13 OAJ20805.1 - 2.2 7.4 4.5 2.9 7.0 4.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 OAJ20805.1 - 6.4 6.0 10.5 14 4.9 10.5 1.6 1 1 0 1 1 1 0 FAM76 protein Dimer_Tnp_hAT PF05699.14 OAJ20807.1 - 1.5e-11 43.9 0.1 3.3e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ20807.1 - 0.1 12.9 1.2 0.14 12.5 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4413) zf-CCCH PF00642.24 OAJ20808.1 - 1.8e-07 30.9 25.8 2.2e-05 24.3 2.3 4.4 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ20808.1 - 0.0067 16.4 24.5 0.047 13.8 2.0 4.5 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 OAJ20808.1 - 0.2 12.4 24.2 0.19 12.5 3.1 3.8 1 1 2 3 3 3 0 Torus domain Chalcone_2 PF16035.5 OAJ20809.1 - 1.5e-36 126.1 1.0 5.1e-34 117.8 1.0 3.0 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAJ20809.1 - 0.00038 20.6 0.1 0.0013 18.9 0.2 1.8 1 1 1 2 2 2 1 Chalcone isomerase-like stn_TNFRSF12A PF12191.8 OAJ20809.1 - 0.11 12.8 0.3 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DEAD PF00270.29 OAJ20810.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase BAR PF03114.18 OAJ20811.1 - 8.8e-50 169.6 1.6 1.1e-49 169.2 1.6 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 OAJ20811.1 - 6.9e-06 25.8 1.1 8.9e-06 25.4 1.1 1.1 1 0 0 1 1 1 1 Arfaptin-like domain Cellulase PF00150.18 OAJ20812.1 - 4e-09 36.3 0.8 1e-08 35.0 0.8 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zip PF02535.22 OAJ20812.1 - 1.3 8.2 11.4 1.9 7.6 11.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SOG2 PF10428.9 OAJ20812.1 - 1.6 7.9 10.5 2.2 7.4 10.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SIR2 PF02146.17 OAJ20813.1 - 1.9e-23 83.3 0.0 1.8e-20 73.6 0.0 2.1 2 0 0 2 2 2 2 Sir2 family RabGAP-TBC PF00566.18 OAJ20814.1 - 2.5e-26 92.7 0.0 6.6e-26 91.3 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4246 PF14033.6 OAJ20815.1 - 3.4e-125 418.7 2.1 4e-125 418.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.9 OAJ20815.1 - 0.0015 18.4 0.0 0.0041 16.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_5 PF13759.6 OAJ20815.1 - 0.0073 16.7 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 OAJ20815.1 - 0.011 16.7 0.0 0.03 15.2 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAJ20816.1 - 1.4e-37 129.4 22.7 2.1e-36 125.6 24.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 OAJ20816.1 - 0.0026 17.1 3.4 0.0026 17.1 3.4 2.5 2 1 0 2 2 2 1 Putative threonine/serine exporter LapA_dom PF06305.11 OAJ20816.1 - 0.46 10.3 0.0 0.46 10.3 0.0 3.7 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain ANAPC15 PF15243.6 OAJ20816.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 15 ABC_membrane PF00664.23 OAJ20817.1 - 5.7e-61 206.6 22.1 7.2e-36 124.2 8.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ20817.1 - 2.1e-50 170.8 2.6 1.8e-26 93.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 OAJ20817.1 - 1.4e-06 28.4 0.3 0.071 13.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ20817.1 - 2e-05 24.2 0.2 0.17 11.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ20817.1 - 3e-05 24.6 7.0 0.32 11.5 0.0 4.2 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.19 OAJ20817.1 - 0.00013 21.5 2.1 2.1 7.7 0.1 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ20817.1 - 0.00035 21.0 1.6 0.024 15.0 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 OAJ20817.1 - 0.00087 19.4 4.5 0.34 10.9 0.0 3.5 3 0 0 3 3 3 2 Dynamin family AAA_21 PF13304.6 OAJ20817.1 - 0.0016 18.3 2.7 0.21 11.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 OAJ20817.1 - 0.002 18.1 2.4 0.55 10.1 0.1 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 OAJ20817.1 - 0.0094 15.7 0.4 1 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 OAJ20817.1 - 0.018 14.6 1.0 0.7 9.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 OAJ20817.1 - 0.028 13.7 1.4 0.59 9.4 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 OAJ20817.1 - 0.031 14.8 0.2 8.8 6.9 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAJ20817.1 - 0.09 12.5 4.7 7.3 6.2 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain NCA2 PF08637.10 OAJ20818.1 - 5.6e-76 255.5 0.0 1.3e-75 254.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Thioredoxin_13 PF18401.1 OAJ20818.1 - 0.35 10.8 2.1 0.87 9.5 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like domain Nrap_D4 PF17405.2 OAJ20819.1 - 2.6e-53 180.5 0.0 4.7e-53 179.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 OAJ20819.1 - 9.2e-43 145.9 0.0 1.5e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 OAJ20819.1 - 7.1e-39 133.4 0.0 1.3e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 OAJ20819.1 - 5.6e-38 130.1 0.1 3.1e-37 127.7 0.0 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 OAJ20819.1 - 1.4e-33 116.0 0.0 2.8e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 OAJ20819.1 - 2.2e-27 95.9 0.0 4.8e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 SDA1 PF05285.12 OAJ20819.1 - 0.17 11.2 23.0 0.29 10.5 23.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ20819.1 - 0.4 10.0 27.5 0.6 9.4 27.5 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ20819.1 - 0.51 8.5 19.6 0.74 8.0 19.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 OAJ20819.1 - 3 6.9 27.6 5.2 6.1 27.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cnd2 PF05786.14 OAJ20819.1 - 9 4.8 16.9 14 4.2 16.9 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF1749 PF08538.10 OAJ20820.1 - 9.5e-47 159.5 0.0 1.9e-44 151.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) GTP-bdg_M PF16360.5 OAJ20820.1 - 0.065 13.8 0.0 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region DEAD PF00270.29 OAJ20821.1 - 1.3e-20 73.9 0.0 1.9e-17 63.6 0.0 3.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20821.1 - 9.1e-05 22.8 0.3 0.00062 20.1 0.3 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20821.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Phage_holin_3_6 PF07332.11 OAJ20823.1 - 0.098 12.7 0.0 0.098 12.7 0.0 2.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III COX2_TM PF02790.15 OAJ20823.1 - 0.13 12.4 3.0 0.31 11.2 0.2 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4013 PF13197.6 OAJ20823.1 - 0.75 9.6 17.7 0.74 9.6 1.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) DUF2393 PF09624.10 OAJ20823.1 - 0.94 9.5 4.5 4.1 7.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) ABC2_membrane_2 PF12679.7 OAJ20823.1 - 4.4 6.5 12.9 5.6 6.2 1.0 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein NPR3 PF03666.13 OAJ20824.1 - 6.3e-82 275.8 0.0 2.8e-48 164.9 0.0 2.6 2 1 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 OAJ20824.1 - 1.9e-05 23.6 0.0 0.49 9.1 0.0 3.7 4 0 0 4 4 4 2 Nitrogen permease regulator 2 DUF3022 PF11226.8 OAJ20824.1 - 0.33 11.4 3.6 2.6 8.5 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) Peptidase_M24 PF00557.24 OAJ20827.1 - 2.5e-39 135.2 0.0 3.4e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 OAJ20827.1 - 0.016 15.4 4.3 0.024 14.7 4.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAJ20827.1 - 0.58 8.4 4.8 0.82 7.9 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ20827.1 - 5.4 6.3 7.4 9.4 5.5 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 OAJ20827.1 - 5.4 6.6 6.6 1.4 8.5 2.9 1.8 3 0 0 3 3 3 0 Surfeit locus protein 2 (SURF2) DUF3245 PF11595.8 OAJ20827.1 - 5.5 7.5 13.6 0.93 10.0 9.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Rotamase PF00639.21 OAJ20828.1 - 8e-19 68.4 0.0 1.7e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAJ20828.1 - 4e-17 62.8 0.0 8.7e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAJ20828.1 - 6.3e-08 32.6 0.6 3.6e-07 30.1 0.2 2.1 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 OAJ20828.1 - 0.083 13.7 0.0 0.16 12.8 0.0 1.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain Yae1_N PF09811.9 OAJ20829.1 - 1.8e-10 40.3 2.0 1.8e-10 40.3 2.0 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal zf-UBR PF02207.20 OAJ20830.1 - 1.1e-15 57.5 14.8 1.1e-15 57.5 14.8 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAJ20830.1 - 1.1e-07 31.5 0.1 4.1e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 OAJ20830.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL ANAPC4_WD40 PF12894.7 OAJ20831.1 - 2.5e-05 24.5 0.0 13 6.1 0.0 4.7 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ20831.1 - 0.00094 20.0 0.2 7.9 7.5 0.0 5.6 7 0 0 7 7 7 1 WD domain, G-beta repeat CPSF100_C PF13299.6 OAJ20831.1 - 0.0056 16.9 2.0 0.0056 16.9 2.0 1.9 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal CDC27 PF09507.10 OAJ20831.1 - 0.04 13.3 10.7 0.058 12.8 10.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 OAJ20831.1 - 0.14 11.5 15.7 0.21 11.0 15.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ20831.1 - 0.75 9.1 18.4 1.2 8.3 18.4 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OAJ20831.1 - 4.9 5.3 13.8 1.4 7.1 11.2 1.3 1 1 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 OAJ20831.1 - 9.1 5.9 9.5 17 5.0 9.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SNARE PF05739.19 OAJ20832.1 - 5.4e-10 39.1 0.1 1.1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ20832.1 - 1.6e-05 24.7 12.3 2e-05 24.4 9.7 2.3 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 OAJ20832.1 - 0.00089 19.6 6.3 0.022 15.1 0.7 2.3 2 0 0 2 2 2 2 Syntaxin-like protein DNA_repr_REX1B PF14966.6 OAJ20832.1 - 0.045 14.4 0.9 0.6 10.8 0.1 2.7 2 0 0 2 2 2 0 DNA repair REX1-B DASH_Dad1 PF08649.10 OAJ20832.1 - 0.16 12.2 0.3 31 4.8 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF1043 PF06295.12 OAJ20832.1 - 0.66 10.0 3.6 9.9 6.2 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) TMPIT PF07851.13 OAJ20832.1 - 0.92 8.7 3.7 1.8 7.7 0.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein Lebercilin PF15619.6 OAJ20832.1 - 1.2 8.7 10.0 0.29 10.8 0.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MIP-T3_C PF17749.1 OAJ20832.1 - 2.5 8.0 7.6 0.31 11.0 2.7 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF2203 PF09969.9 OAJ20832.1 - 4.5 8.0 6.1 5.4 7.7 1.2 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Diphthamide_syn PF01866.17 OAJ20833.1 - 2.5e-74 250.5 0.0 3.2e-39 135.2 0.0 3.1 2 1 0 2 2 2 2 Putative diphthamide synthesis protein PAP_assoc PF03828.19 OAJ20834.1 - 1.3e-14 54.2 0.0 3.1e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ20834.1 - 1.3e-09 38.2 0.0 3.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DEAD PF00270.29 OAJ20835.1 - 1.2e-49 168.4 0.0 3.1e-49 167.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20835.1 - 3.5e-27 94.9 0.0 2.5e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ20835.1 - 0.0057 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 OAJ20858.1 - 2.8e-28 97.5 0.2 1.9e-16 59.6 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ20858.1 - 0.00024 21.1 0.0 0.00024 21.1 0.0 2.6 3 0 0 3 3 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ20858.1 - 0.0025 17.8 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ20858.1 - 0.034 14.3 0.1 1.4 9.1 0.1 2.8 2 0 0 2 2 2 0 RNA recognition motif Pex14_N PF04695.13 OAJ20858.1 - 0.047 14.3 42.0 0.27 11.9 23.9 3.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LMBR1 PF04791.16 OAJ20858.1 - 0.075 11.9 5.3 0.1 11.5 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RRM_occluded PF16842.5 OAJ20858.1 - 0.15 11.9 0.0 0.63 9.9 0.0 2.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif EOS1 PF12326.8 OAJ20858.1 - 0.38 10.7 2.9 0.91 9.4 2.9 1.7 1 0 0 1 1 1 0 N-glycosylation protein PAT1 PF09770.9 OAJ20858.1 - 3.2 5.9 47.6 0.45 8.7 28.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2828 PF11443.8 OAJ20858.1 - 7.9 4.4 15.5 14 3.6 15.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Membralin PF09746.9 OAJ20858.1 - 9.2 5.2 11.1 17 4.3 11.1 1.3 1 0 0 1 1 1 0 Tumour-associated protein Rhodanese PF00581.20 OAJ20861.1 - 1.8e-13 50.9 0.0 2.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.26 OAJ20862.1 - 0.00045 20.5 11.2 0.024 15.1 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ20862.1 - 0.00069 19.9 9.6 0.0027 18.1 1.3 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 OAJ20862.1 - 0.034 14.4 0.6 0.36 11.2 0.6 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon Aim19 PF10315.9 OAJ20864.1 - 7.7e-19 68.1 7.6 3.2e-17 62.9 7.6 2.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Snf7 PF03357.21 OAJ20865.1 - 1.6e-11 44.1 13.3 2e-11 43.8 13.3 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 OAJ20865.1 - 0.0025 17.8 3.0 0.0039 17.1 3.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 OAJ20865.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase SYCE1 PF15233.6 OAJ20865.1 - 0.22 11.6 6.8 0.039 14.0 2.3 2.0 1 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Proteasome PF00227.26 OAJ20866.1 - 5.4e-39 133.7 0.1 6.1e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_S13 PF00416.22 OAJ20867.1 - 6e-21 75.2 0.0 4.9e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 OAJ20867.1 - 0.002 17.0 0.0 0.0026 16.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) CX9C PF16860.5 OAJ20868.1 - 0.00017 21.5 2.0 0.31 11.1 0.3 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAJ20868.1 - 0.031 14.3 0.6 0.15 12.1 1.0 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 OAJ20868.1 - 0.063 13.5 0.4 0.15 12.3 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Abhydrolase_3 PF07859.13 OAJ20870.1 - 6.6e-14 52.3 0.0 1.4e-09 38.1 0.1 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ20870.1 - 3.3e-07 30.0 0.1 5.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OAJ20870.1 - 0.00065 18.7 0.0 0.00094 18.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family CSN8_PSD8_EIF3K PF10075.9 OAJ20871.1 - 7.7e-31 107.0 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAJ20871.1 - 8.3e-08 32.0 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family PPR_2 PF13041.6 OAJ20872.1 - 1.6e-10 41.0 0.0 1.7e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 OAJ20872.1 - 0.0005 20.1 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 OAJ20872.1 - 0.071 13.4 0.2 0.7 10.3 0.0 2.8 3 0 0 3 3 3 0 PPR repeat RRM_1 PF00076.22 OAJ20873.1 - 2.3e-55 184.3 0.0 1.4e-19 69.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ20873.1 - 3.1e-08 33.2 0.0 0.03 13.9 0.0 4.0 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ20873.1 - 2.1e-05 24.3 0.0 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ20873.1 - 9.4e-05 22.5 0.0 0.12 12.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ20873.1 - 0.0002 21.3 0.1 1.6 8.8 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 OAJ20873.1 - 0.052 13.6 0.0 12 6.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) SET_assoc PF11767.8 OAJ20873.1 - 0.26 11.0 0.0 9.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated AAA PF00004.29 OAJ20874.1 - 4.8e-44 150.0 0.1 1.1e-43 148.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ20874.1 - 3.5e-09 36.5 0.6 1.7e-08 34.3 0.0 2.4 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ20874.1 - 3e-08 33.8 0.1 1e-07 32.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ20874.1 - 1.3e-07 32.2 0.9 4.2e-05 24.0 0.0 3.2 3 1 1 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ20874.1 - 2.1e-07 31.2 0.1 6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 OAJ20874.1 - 2.7e-06 27.1 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 OAJ20874.1 - 1.5e-05 24.3 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ20874.1 - 6.2e-05 23.3 0.6 0.013 15.8 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ20874.1 - 0.00032 20.5 0.0 0.00081 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ20874.1 - 0.00073 20.1 0.0 0.0041 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ20874.1 - 0.00081 19.7 0.1 0.0024 18.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 OAJ20874.1 - 0.00088 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 OAJ20874.1 - 0.0011 18.9 0.1 0.0027 17.7 0.0 1.7 2 0 0 2 2 1 1 NTPase TIP49 PF06068.13 OAJ20874.1 - 0.0022 17.2 0.0 0.0055 16.0 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ20874.1 - 0.0028 17.7 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ20874.1 - 0.0047 17.1 0.0 0.015 15.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAJ20874.1 - 0.0051 16.3 0.1 0.029 13.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ20874.1 - 0.0056 17.0 0.0 0.015 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 OAJ20874.1 - 0.0058 16.0 0.1 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ20874.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ20874.1 - 0.015 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ20874.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 OAJ20874.1 - 0.019 14.9 0.1 0.092 12.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 OAJ20874.1 - 0.024 14.1 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 OAJ20874.1 - 0.026 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 OAJ20874.1 - 0.037 13.7 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain ATPase_2 PF01637.18 OAJ20874.1 - 0.04 13.8 0.7 0.5 10.2 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 OAJ20874.1 - 0.055 14.0 0.6 0.53 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 OAJ20874.1 - 0.057 13.2 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAJ20874.1 - 0.065 12.3 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ20874.1 - 0.076 12.6 0.5 0.37 10.3 0.1 1.8 1 1 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 OAJ20874.1 - 0.079 11.8 0.1 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 OAJ20874.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_29 PF13555.6 OAJ20874.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAJ20874.1 - 0.17 11.6 0.2 1.8 8.3 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 OAJ20874.1 - 0.17 12.2 0.1 0.5 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain GIT_CC PF16559.5 OAJ20876.1 - 0.44 10.4 18.5 0.092 12.6 0.7 4.6 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 OAJ20876.1 - 8.1 7.2 23.8 2 9.1 0.0 4.7 4 1 1 5 5 5 0 Initiation control protein YabA Tcp11 PF05794.13 OAJ20878.1 - 5.1e-08 32.4 3.1 3.4e-06 26.4 0.0 2.4 1 1 0 2 2 2 2 T-complex protein 11 Sod_Fe_C PF02777.18 OAJ20879.1 - 2.7e-34 117.4 0.1 5.4e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ20879.1 - 3.1e-32 110.9 2.6 5.3e-32 110.1 2.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 OAJ20879.1 - 0.12 12.5 0.1 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_hydro_cc PF11790.8 OAJ20880.1 - 7.3e-52 176.3 1.4 1e-51 175.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Dus PF01207.17 OAJ20881.1 - 1.2e-48 165.8 0.0 8.3e-33 113.8 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 OAJ20881.1 - 5.2e-06 26.2 4.0 0.0067 16.3 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAJ20881.1 - 9.8e-06 25.3 7.7 0.00014 21.6 2.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ20881.1 - 2.6e-05 24.1 10.0 0.0011 19.0 3.2 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 OAJ20881.1 - 3.2e-05 24.6 0.5 0.0047 17.6 0.3 2.5 2 0 0 2 2 2 1 Torus domain Lustrin_cystein PF14625.6 OAJ20881.1 - 0.069 13.5 0.3 23 5.4 0.0 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.6 OAJ20881.1 - 7.3 7.2 6.9 0.86 10.2 2.3 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Epimerase PF01370.21 OAJ20882.1 - 0.00024 20.6 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ20882.1 - 0.0069 16.3 0.3 0.033 14.1 0.0 2.3 3 0 0 3 3 3 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAJ20882.1 - 0.048 12.7 0.0 0.095 11.7 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ20882.1 - 0.064 12.3 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain EXS PF03124.14 OAJ20884.1 - 1.7e-83 280.7 30.8 2.5e-83 280.1 30.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OAJ20884.1 - 1e-45 157.4 17.2 1e-45 157.4 17.2 2.0 2 1 0 2 2 2 1 SPX domain DUF1993 PF09351.10 OAJ20884.1 - 0.082 13.0 2.7 8.4 6.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) He_PIG PF05345.12 OAJ20885.1 - 3.6e-11 43.1 20.0 4.2e-07 30.0 0.1 4.6 4 0 0 4 4 4 3 Putative Ig domain SEEK1 PF15357.6 OAJ20886.1 - 0.11 12.6 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 GTP_EFTU PF00009.27 OAJ20887.1 - 1.1e-49 168.6 0.0 1.9e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAJ20887.1 - 6.8e-21 74.1 0.5 6.5e-10 39.0 0.0 2.8 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.24 OAJ20887.1 - 1.2e-16 60.4 0.3 2.5e-08 33.9 0.0 2.4 1 1 1 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ20887.1 - 2.4e-08 34.2 0.0 5.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ20887.1 - 0.00033 20.5 0.1 0.0006 19.6 0.1 1.3 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 OAJ20887.1 - 0.026 14.3 0.0 0.93 9.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor G, domain IV AvrPtoB_bdg PF16847.5 OAJ20887.1 - 0.077 13.5 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MRP-S25 PF13741.6 OAJ20888.1 - 1.2e-50 172.2 0.4 2.5e-50 171.2 0.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAJ20888.1 - 6.6e-07 29.6 0.3 0.0013 18.9 0.0 2.5 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 Lipase_chap PF03280.14 OAJ20888.1 - 0.19 11.7 6.7 0.021 14.8 2.4 1.6 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein GN3L_Grn1 PF08701.11 OAJ20889.1 - 1.6e-20 72.9 19.6 1.6e-20 72.9 19.6 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase BUD22 PF09073.10 OAJ20889.1 - 0.08 12.3 26.9 0.1 12.0 26.9 1.2 1 0 0 1 1 1 0 BUD22 Mit_KHE1 PF10173.9 OAJ20889.1 - 3.8 7.5 8.2 4.2 7.4 7.3 1.4 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related GLE1 PF07817.13 OAJ20890.1 - 1e-71 241.1 0.1 1.6e-71 240.5 0.1 1.3 1 0 0 1 1 1 1 GLE1-like protein eIF3_subunit PF08597.10 OAJ20890.1 - 8.3e-06 25.9 17.1 8.3e-06 25.9 17.1 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit DUF4746 PF15928.5 OAJ20890.1 - 0.16 11.4 13.6 0.29 10.5 13.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 OAJ20890.1 - 0.25 11.5 4.4 0.85 9.7 4.4 2.0 1 0 0 1 1 1 0 DDHD domain DUF4407 PF14362.6 OAJ20890.1 - 0.26 10.6 12.6 0.61 9.4 12.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 OAJ20890.1 - 0.55 10.0 15.2 1.7 8.4 15.2 1.9 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 OAJ20890.1 - 0.97 9.5 17.4 2.5 8.2 17.4 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Spore_coat_CotO PF14153.6 OAJ20890.1 - 1.6 8.6 15.4 3.2 7.6 15.4 1.5 1 0 0 1 1 1 0 Spore coat protein CotO PA26 PF04636.13 OAJ20890.1 - 2.2 7.1 5.1 3.7 6.4 5.1 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) U79_P34 PF03064.16 OAJ20890.1 - 5.3 6.3 14.8 11 5.3 14.8 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 OAJ20890.1 - 8.6 5.0 13.7 18 3.9 13.7 1.4 1 0 0 1 1 1 0 Presenilin OGG_N PF07934.12 OAJ20891.1 - 1.4e-22 80.0 0.0 6e-21 74.8 0.0 2.2 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 OAJ20891.1 - 2.4e-11 44.0 0.0 7.8e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ20891.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif NmrA PF05368.13 OAJ20892.1 - 2.5e-10 40.3 0.1 0.00018 21.1 0.0 3.2 3 0 0 3 3 3 3 NmrA-like family NAD_binding_10 PF13460.6 OAJ20892.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF1416 PF07210.12 OAJ20892.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Cullin_binding PF03556.15 OAJ20894.1 - 1.2e-31 109.7 0.1 2.4e-31 108.7 0.1 1.5 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 OAJ20894.1 - 2.7e-09 36.7 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Herpes_UL21 PF03252.13 OAJ20894.1 - 0.071 11.8 0.3 0.11 11.3 0.1 1.3 2 0 0 2 2 2 0 Herpesvirus UL21 zf-CCHC PF00098.23 OAJ20895.1 - 3.9e-33 112.0 44.4 5.9e-07 29.3 0.3 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ20895.1 - 4.9e-08 32.6 35.5 0.013 15.3 0.4 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ20895.1 - 2.4e-06 27.2 40.1 0.0036 17.1 0.1 6.3 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ20895.1 - 2.1e-05 24.4 33.9 0.16 12.0 0.4 6.1 2 2 4 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ20895.1 - 0.00013 21.6 33.9 0.0043 16.7 1.0 6.0 5 1 1 6 6 6 4 GAG-polyprotein viral zinc-finger Ntox16 PF15523.6 OAJ20895.1 - 2.3 8.5 13.8 20 5.5 0.5 4.4 3 1 2 5 5 5 0 Novel toxin 16 Abhydrolase_6 PF12697.7 OAJ20896.1 - 1e-05 26.3 3.6 1e-05 26.3 3.6 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 OAJ20896.1 - 0.18 10.3 0.0 0.25 9.8 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II HAD_2 PF13419.6 OAJ20913.1 - 5.8e-17 62.3 0.0 1.9e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ20913.1 - 1.5e-14 54.8 0.6 5.7e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ20913.1 - 3.5e-05 23.8 0.0 7.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAJ20913.1 - 0.028 14.8 0.1 0.59 10.5 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Y_phosphatase2 PF03162.13 OAJ20914.1 - 4.4e-30 104.4 0.0 5.1e-23 81.5 0.0 3.2 3 0 0 3 3 3 3 Tyrosine phosphatase family SseC PF04888.12 OAJ20914.1 - 0.52 9.8 5.0 0.79 9.3 5.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SPT6_acidic PF14632.6 OAJ20915.1 - 0.02 15.5 1.7 0.61 10.7 0.1 2.8 2 1 0 2 2 2 0 Acidic N-terminal SPT6 DDHD PF02862.17 OAJ20917.1 - 5.2e-26 92.2 5.0 5.2e-24 85.7 0.0 3.3 3 1 0 3 3 3 2 DDHD domain PAS_9 PF13426.7 OAJ20918.1 - 1.1e-18 67.4 0.0 7.3e-18 64.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 OAJ20918.1 - 5.4e-08 32.8 0.0 1.7e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAJ20918.1 - 1.7e-05 25.1 0.0 0.00027 21.2 0.0 2.5 2 1 0 2 2 2 1 PAS fold RGS PF00615.19 OAJ20918.1 - 3.9e-05 23.9 0.0 7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_3 PF08447.12 OAJ20918.1 - 5.3e-05 23.4 0.0 0.00049 20.3 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OAJ20918.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 PAS domain adh_short_C2 PF13561.6 OAJ20919.1 - 3.3e-47 161.0 1.1 4.5e-47 160.6 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ20919.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ20919.1 - 1.2e-08 35.0 0.1 2e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Chitin_synth_2 PF03142.15 OAJ20922.1 - 3.2e-282 936.8 0.1 3.9e-282 936.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 OAJ20922.1 - 8.3e-13 48.8 0.1 2e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ20922.1 - 2.5e-11 43.8 1.0 7.2e-11 42.4 1.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ20922.1 - 0.00082 18.9 0.1 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ20922.1 - 0.014 15.2 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 PAS_9 PF13426.7 OAJ20923.1 - 5.1e-18 65.2 0.0 1.3e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAJ20923.1 - 9.1e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold RGS PF00615.19 OAJ20923.1 - 3.9e-06 27.1 0.0 6.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.10 OAJ20923.1 - 1.4e-05 25.3 0.0 0.0003 21.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 OAJ20923.1 - 0.00019 21.6 0.0 0.00063 20.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 OAJ20923.1 - 0.087 12.9 0.0 0.31 11.1 0.0 2.0 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 OAJ20924.1 - 2.4e-18 66.3 0.0 7.4e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAJ20924.1 - 3.3e-08 33.5 0.0 1.8e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 PAS fold RGS PF00615.19 OAJ20924.1 - 5.2e-07 30.0 0.1 1.5e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS_3 PF08447.12 OAJ20924.1 - 3.3e-05 24.1 0.0 0.00049 20.3 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAJ20924.1 - 5.1e-05 23.5 0.0 0.00028 21.1 0.0 2.2 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 OAJ20924.1 - 0.081 13.0 0.0 0.3 11.1 0.0 2.0 1 0 0 1 1 1 0 PAS domain Stevor PF17410.2 OAJ20925.1 - 0.038 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame GDPD PF03009.17 OAJ20926.1 - 1.4e-29 103.6 0.6 5.1e-29 101.8 0.6 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 OAJ20926.1 - 3.7e-05 24.0 1.9 0.00011 22.5 1.9 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Rho_RNA_bind PF07497.12 OAJ20926.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Rho termination factor, RNA-binding domain DUF3533 PF12051.8 OAJ20927.1 - 1.4e-72 244.8 14.3 1.6e-72 244.6 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) XFP PF03894.15 OAJ20927.1 - 0.029 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase WD40 PF00400.32 OAJ20929.1 - 4.7e-33 112.7 9.2 1.1e-06 29.3 0.9 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 OAJ20929.1 - 1.9e-10 40.4 0.1 6.5e-10 38.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ20929.1 - 0.00018 21.3 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 OAJ20929.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box WD40_like PF17005.5 OAJ20929.1 - 0.0088 15.4 0.0 0.16 11.2 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Abhydrolase_9_N PF15420.6 OAJ20930.1 - 0.022 14.8 5.1 1.5 8.7 0.3 3.2 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF373 PF04123.13 OAJ20930.1 - 4.5 6.6 6.9 21 4.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF373) Ferrochelatase PF00762.19 OAJ20931.1 - 0.062 12.4 0.4 0.64 9.0 0.1 2.2 2 0 0 2 2 2 0 Ferrochelatase REV1_C PF16727.5 OAJ20931.1 - 0.13 12.6 0.1 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain HR1 PF02185.16 OAJ20931.1 - 2.9 8.1 11.0 1.2 9.3 0.1 3.6 3 0 0 3 3 3 0 Hr1 repeat adh_short PF00106.25 OAJ20932.1 - 4.1e-86 287.4 16.0 6e-43 146.6 3.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ20932.1 - 2.1e-70 236.9 16.5 3.9e-35 121.5 5.0 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAJ20932.1 - 1.6e-30 105.2 0.0 3.4e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAJ20932.1 - 1e-28 100.5 9.0 1.4e-14 54.5 1.4 2.4 2 0 0 2 2 2 2 KR domain MULE PF10551.9 OAJ20932.1 - 4.9e-19 68.5 0.4 2.7e-18 66.1 0.4 2.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ20932.1 - 1e-05 24.6 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family THF_DHG_CYH_C PF02882.19 OAJ20932.1 - 0.0001 21.7 0.3 0.066 12.5 0.1 2.8 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 OAJ20932.1 - 0.00054 19.4 4.5 0.19 11.1 0.1 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MaoC_dehydrat_N PF13452.6 OAJ20932.1 - 0.0011 19.1 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 OAJ20932.1 - 0.0093 15.9 11.4 0.086 12.7 1.7 2.7 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 OAJ20932.1 - 0.51 10.2 2.6 0.41 10.5 0.2 2.1 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF543 PF04418.12 OAJ20932.1 - 2.3 8.3 6.5 8.1 6.5 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) FAM25 PF15825.5 OAJ20932.1 - 3.8 7.9 6.6 1.5 9.2 1.6 2.7 2 0 0 2 2 2 0 FAM25 family PglL_A PF15864.5 OAJ20932.1 - 4.6 7.1 8.2 15 5.4 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase ADH_zinc_N PF00107.26 OAJ20932.1 - 7 6.6 7.1 7 6.6 1.5 2.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase PLDc_2 PF13091.6 OAJ20933.1 - 3.1e-17 62.7 0.0 1.8e-11 44.0 0.0 3.1 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 OAJ20933.1 - 0.054 13.7 0.2 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase D Active site motif MMR_HSR1_Xtn PF16897.5 OAJ20934.1 - 1.7e-39 134.1 0.1 4e-39 132.9 0.2 1.6 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAJ20934.1 - 1.1e-23 83.0 0.0 2.1e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAJ20934.1 - 9.7e-21 74.0 0.1 2.2e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ20934.1 - 1e-09 38.1 0.2 3.2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ20934.1 - 0.001 19.2 0.1 0.31 11.1 0.0 2.6 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 OAJ20934.1 - 0.024 13.6 0.9 0.052 12.5 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OAJ20934.1 - 0.07 12.7 0.7 18 4.8 0.1 3.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 OAJ20934.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 OAJ20934.1 - 0.22 11.4 0.9 6 6.7 0.0 2.8 2 1 1 3 3 3 0 RsgA GTPase Spo12 PF05032.12 OAJ20937.1 - 8.8e-14 51.1 4.6 2.2e-13 49.8 4.6 1.7 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.7 OAJ20937.1 - 0.0022 18.6 0.0 0.0033 18.1 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAJ20937.1 - 0.18 11.6 0.0 0.46 10.3 0.0 1.6 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase WD40 PF00400.32 OAJ20938.1 - 6.6e-19 67.9 2.4 4e-05 24.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ20938.1 - 0.0026 18.0 0.0 1.8 8.9 0.0 4.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAJ20938.1 - 0.016 15.1 0.9 0.073 13.0 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFIIB PF00382.19 OAJ20939.1 - 8.8e-27 93.0 0.1 5.2e-18 64.9 0.1 3.0 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAJ20939.1 - 1.2e-25 89.8 4.3 1.2e-25 89.8 4.3 4.6 5 2 0 5 5 5 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OAJ20939.1 - 1.6e-07 30.7 1.0 3.3e-07 29.7 1.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OAJ20939.1 - 3.2e-05 23.7 0.1 0.37 10.5 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Ribosomal_S27e PF01667.17 OAJ20939.1 - 0.14 11.9 0.7 0.25 11.1 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.13 OAJ20939.1 - 0.64 9.7 4.2 1.3 8.7 4.2 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Sds3 PF08598.11 OAJ20940.1 - 5.7e-28 98.4 1.8 5.7e-28 98.4 1.8 2.3 2 1 0 2 2 2 1 Sds3-like Pes-10 PF07149.11 OAJ20940.1 - 1.9 7.5 10.5 0.61 9.1 7.6 1.7 2 0 0 2 2 2 0 Pes-10 CoA_trans PF01144.23 OAJ20941.1 - 1.8e-102 341.4 0.1 3.2e-62 209.8 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 OAJ20941.1 - 0.18 10.1 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter ubiquitin PF00240.23 OAJ20942.1 - 8.6e-25 86.3 0.1 9.5e-25 86.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ20942.1 - 1.2e-13 50.7 0.0 1.3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ20942.1 - 0.0004 20.8 0.0 0.00048 20.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ20942.1 - 0.0038 17.1 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HATPase_c PF02518.26 OAJ20942.1 - 0.016 15.7 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_31 PF13847.6 OAJ20943.1 - 1.4e-14 54.2 0.0 1.9e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ20943.1 - 8.7e-08 32.8 0.0 1.6e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ20943.1 - 5.8e-07 30.1 0.0 1.8e-06 28.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ20943.1 - 3.5e-05 23.7 0.0 4.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAJ20943.1 - 4.6e-05 23.5 0.0 6.2e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ20943.1 - 0.0006 20.4 0.0 0.0022 18.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 OAJ20943.1 - 0.051 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Las1 PF04031.13 OAJ20944.1 - 4.9e-43 146.9 0.4 5.9e-43 146.6 0.4 1.1 1 0 0 1 1 1 1 Las1-like Cpn60_TCP1 PF00118.24 OAJ20945.1 - 2.2e-158 527.9 1.1 2.6e-158 527.7 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acyl-CoA_dh_1 PF00441.24 OAJ20966.1 - 8.4e-49 165.6 5.6 8.4e-49 165.6 5.6 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ20966.1 - 1.2e-27 96.0 0.5 2.6e-27 94.9 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ20966.1 - 2.4e-25 89.4 0.3 2.4e-25 89.4 0.3 2.5 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ20966.1 - 2.9e-19 69.7 6.0 2.9e-19 69.7 6.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAJ20966.1 - 0.00026 20.8 0.1 0.00099 18.9 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal GATA PF00320.27 OAJ20967.1 - 1.1e-14 53.7 7.8 2.5e-14 52.6 7.8 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAJ20967.1 - 0.0084 15.6 1.6 0.016 14.8 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Auto_anti-p27 PF06677.12 OAJ20967.1 - 0.18 12.0 0.4 0.29 11.3 0.4 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 OAJ20967.1 - 0.27 10.7 1.8 4.3 6.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Cupin_5 PF06172.11 OAJ20968.1 - 2.1e-31 109.0 0.0 9.5e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) Ribosomal_L6 PF00347.23 OAJ20969.1 - 4.7e-24 84.9 2.6 4.9e-12 46.3 0.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 CTD_bind PF04818.13 OAJ20970.1 - 0.039 14.8 0.0 0.11 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 OAJ20970.1 - 0.093 13.2 2.8 0.16 12.4 0.5 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 OAJ20970.1 - 3.1 7.5 12.1 6.2 6.5 6.6 3.0 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-CRD PF17979.1 OAJ20972.1 - 2.2e-07 31.1 0.0 1.5e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions Serglycin PF04360.12 OAJ20972.1 - 0.24 11.4 6.6 1.6 8.7 2.1 2.4 2 0 0 2 2 2 0 Serglycin SKN1 PF03935.15 OAJ20973.1 - 2e-156 521.3 0.3 2.7e-156 520.9 0.3 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DASH_Ask1 PF08655.10 OAJ20974.1 - 5.5e-28 96.7 0.0 8.2e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Asp PF00026.23 OAJ20975.1 - 3e-30 105.7 0.1 1.6e-20 73.8 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TFIIA PF03153.13 OAJ20975.1 - 0.0024 17.9 3.6 0.0034 17.5 3.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ20975.1 - 0.016 14.8 9.2 0.024 14.2 9.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 OAJ20975.1 - 0.017 14.1 4.9 0.026 13.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNase_NucA_NucB PF14040.6 OAJ20976.1 - 1.8e-25 89.6 1.9 2.5e-25 89.1 1.9 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Snf7 PF03357.21 OAJ20977.1 - 1.5e-20 73.5 2.5 2.2e-20 73.0 2.5 1.2 1 0 0 1 1 1 1 Snf7 Upf2 PF04050.14 OAJ20977.1 - 0.026 15.3 0.2 0.067 13.9 0.2 1.6 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Baculo_PEP_C PF04513.12 OAJ20977.1 - 2.7 8.0 5.0 3.4 7.7 0.2 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phosphodiest PF01663.22 OAJ20978.1 - 7.9e-60 203.3 0.0 9.3e-58 196.5 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAJ20978.1 - 0.09 12.1 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DEAD PF00270.29 OAJ20979.1 - 3.5e-32 111.6 0.1 1.5e-31 109.5 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ20979.1 - 3.9e-25 88.4 0.0 1.3e-24 86.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIA PF03153.13 OAJ20979.1 - 0.61 10.0 24.9 1.6 8.7 24.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KdpC PF02669.15 OAJ20979.1 - 8.4 6.2 7.4 1.5 8.6 3.3 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain CAP_GLY PF01302.25 OAJ20980.1 - 1.7e-14 53.6 0.2 2.9e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain KASH_CCD PF14662.6 OAJ20980.1 - 0.0003 20.7 12.1 0.0003 20.7 12.1 5.6 4 2 1 5 5 5 2 Coiled-coil region of CCDC155 or KASH zf-CCHC_4 PF14392.6 OAJ20980.1 - 0.033 13.9 4.6 0.18 11.6 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 OAJ20980.1 - 4 7.7 6.4 4.5 7.5 2.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn_clus PF00172.18 OAJ20981.1 - 1.2e-08 34.9 7.7 1.9e-08 34.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L36e PF01158.18 OAJ20982.1 - 1.3e-38 131.1 6.1 1.6e-38 130.8 6.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L1 PF00687.21 OAJ20983.1 - 5.6e-47 160.1 0.0 1e-46 159.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Exonuc_VII_L PF02601.15 OAJ20983.1 - 0.1 12.1 1.7 0.19 11.3 1.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cwf_Cwc_15 PF04889.12 OAJ20983.1 - 0.15 11.8 15.6 0.28 10.9 15.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1168 PF06658.12 OAJ20983.1 - 0.56 10.0 14.7 1.6 8.6 14.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) RNA_pol_3_Rpc31 PF11705.8 OAJ20983.1 - 1 9.6 19.7 1.9 8.7 19.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 OAJ20983.1 - 2.8 6.4 5.7 3.8 5.9 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4337 PF14235.6 OAJ20983.1 - 3.7 7.6 5.2 6.9 6.8 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) NOA36 PF06524.12 OAJ20983.1 - 6.2 6.1 16.8 8.4 5.6 16.8 1.2 1 0 0 1 1 1 0 NOA36 protein Rad17 PF03215.15 OAJ20984.1 - 1.3e-17 64.4 0.0 3e-15 56.6 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 OAJ20984.1 - 0.00028 21.3 0.6 0.0017 18.8 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ20984.1 - 0.0024 18.1 0.0 0.0077 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 OAJ20984.1 - 0.019 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 OAJ20984.1 - 0.033 14.7 0.0 0.069 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 OAJ20984.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ20984.1 - 0.066 13.8 0.0 0.23 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ20984.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Parvo_coat PF00740.18 OAJ20984.1 - 8.1 5.0 7.2 0.31 9.6 1.1 1.6 2 0 0 2 2 2 0 Parvovirus coat protein VP2 TFIID_20kDa PF03847.13 OAJ20987.1 - 5.1e-32 110.2 0.7 7.7e-32 109.6 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OAJ20987.1 - 0.0065 16.7 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ20987.1 - 0.0087 16.1 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 OAJ20987.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.2 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Occludin_ELL PF07303.13 OAJ20987.1 - 0.24 12.1 0.0 0.24 12.1 0.0 2.2 3 0 0 3 3 3 0 Occludin homology domain ORC4_C PF14629.6 OAJ20989.1 - 5.3e-27 94.6 0.0 9.6e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAJ20989.1 - 0.00036 20.9 0.2 0.0021 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 OAJ20989.1 - 0.083 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Thioredoxin PF00085.20 OAJ20992.1 - 6.5e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3417 PF11897.8 OAJ20992.1 - 0.13 12.7 0.3 0.22 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) PLDc PF00614.22 OAJ20993.1 - 4.6e-16 58.3 0.2 6e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAJ20993.1 - 4.1e-12 46.1 0.0 9.9e-07 28.7 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAJ20993.1 - 8.8e-09 35.3 0.0 2.4e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.29 OAJ20993.1 - 0.051 14.1 0.1 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF4297 PF14130.6 OAJ20993.1 - 0.2 11.8 1.3 0.38 10.9 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) DUF4149 PF13664.6 OAJ20994.1 - 1.6e-20 73.3 3.3 1.6e-20 73.3 3.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) FRG1 PF06229.12 OAJ20996.1 - 1.9e-20 73.4 1.2 3.5e-08 33.4 0.0 3.2 2 1 1 3 3 3 3 FRG1-like domain Fascin PF06268.13 OAJ20996.1 - 4.6e-06 26.8 0.0 0.077 13.2 0.0 2.4 2 0 0 2 2 2 2 Fascin domain CAP_GLY PF01302.25 OAJ20997.1 - 7.9e-19 67.4 0.1 1.7e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 OAJ20997.1 - 0.0038 17.6 7.2 0.68 10.4 0.6 4.7 3 2 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ20997.1 - 0.0073 16.1 6.1 0.86 9.4 0.4 4.8 3 2 0 4 4 4 1 Leucine rich repeat LRR_6 PF13516.6 OAJ20997.1 - 0.13 12.4 0.4 3.2 8.0 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PUF PF00806.19 OAJ20998.1 - 4.9e-17 60.6 0.4 3.2e-07 29.7 0.0 5.9 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat SLT_2 PF13406.6 OAJ20998.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain SNARE_assoc PF09335.11 OAJ20999.1 - 3.3e-13 50.2 1.9 5.9e-13 49.4 1.9 1.4 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF676 PF05057.14 OAJ21000.1 - 0.00037 20.1 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OAJ21000.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAJ21000.1 - 0.026 14.2 1.6 0.22 11.1 1.6 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ21000.1 - 0.033 14.8 0.1 0.082 13.5 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ21000.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein Alk_phosphatase PF00245.20 OAJ21001.1 - 0.0038 16.2 0.0 0.0079 15.2 0.0 1.5 2 0 0 2 2 2 1 Alkaline phosphatase PLDc_N PF13396.6 OAJ21001.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal UEV PF05743.13 OAJ21022.1 - 1.4e-38 131.5 0.1 2.1e-38 130.9 0.1 1.3 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 OAJ21022.1 - 0.0037 16.9 0.1 0.0065 16.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TMEM208_SND2 PF05620.11 OAJ21023.1 - 5.1e-40 137.0 1.3 8.4e-40 136.3 1.3 1.3 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ribosomal_S28e PF01200.18 OAJ21024.1 - 2.2e-31 107.6 0.6 2.5e-31 107.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Pec_lyase_C PF00544.19 OAJ21024.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Pectate lyase Glyco_transf_22 PF03901.17 OAJ21025.1 - 7.9e-68 229.6 10.7 9.5e-66 222.7 10.7 2.6 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family nlz1 PF12402.8 OAJ21025.1 - 0.048 14.1 1.3 7.8 7.0 0.0 3.1 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 LapA_dom PF06305.11 OAJ21025.1 - 1.7 8.5 4.3 5.8 6.8 0.4 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Rep_fac_C PF08542.11 OAJ21026.1 - 2.4e-25 88.7 0.0 4.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAJ21026.1 - 2.2e-12 47.6 0.0 4.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ21026.1 - 2.5e-12 46.9 0.0 2.2e-10 40.6 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OAJ21026.1 - 3e-07 31.0 0.1 2.1e-05 24.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 OAJ21026.1 - 2.4e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ21026.1 - 1.1e-05 25.4 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ21026.1 - 2.1e-05 24.8 0.1 0.051 13.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_assoc_2 PF16193.5 OAJ21026.1 - 0.00013 22.2 0.1 0.16 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA C-terminal domain Rad17 PF03215.15 OAJ21026.1 - 0.00015 21.8 0.0 0.00037 20.5 0.0 1.6 1 1 1 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 OAJ21026.1 - 0.00023 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MeaB PF03308.16 OAJ21026.1 - 0.00026 20.1 0.0 0.0005 19.1 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 OAJ21026.1 - 0.0017 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OAJ21026.1 - 0.0038 17.0 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 OAJ21026.1 - 0.0065 16.4 0.0 0.064 13.2 0.0 2.2 1 1 1 2 2 2 1 NTPase AAA_24 PF13479.6 OAJ21026.1 - 0.0069 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ21026.1 - 0.011 15.1 0.0 0.092 12.1 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MipZ PF09140.11 OAJ21026.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ TniB PF05621.11 OAJ21026.1 - 0.025 14.0 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 OAJ21026.1 - 0.026 13.7 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRP54 PF00448.22 OAJ21026.1 - 0.028 14.1 0.1 0.085 12.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 OAJ21026.1 - 0.029 14.7 0.1 0.08 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 OAJ21026.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 OAJ21026.1 - 0.037 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 OAJ21026.1 - 0.043 13.6 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 OAJ21026.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF5119 PF17145.4 OAJ21026.1 - 0.089 12.7 0.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) AAA_11 PF13086.6 OAJ21026.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 OAJ21026.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 OAJ21026.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family SNF2_N PF00176.23 OAJ21027.1 - 5.2e-49 166.8 0.0 5.2e-49 166.8 0.0 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ21027.1 - 8.6e-20 71.1 0.0 3.4e-19 69.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 OAJ21027.1 - 2.2e-09 37.1 4.3 0.0004 20.2 0.1 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 OAJ21027.1 - 6.9e-07 29.1 4.4 0.019 14.8 0.1 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAJ21027.1 - 0.0034 17.0 0.2 0.0034 17.0 0.2 5.3 3 1 1 5 5 5 2 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 OAJ21027.1 - 0.41 10.8 3.9 4.2 7.5 0.1 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger PX PF00787.24 OAJ21028.1 - 2.5e-19 69.3 0.0 4.7e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 PX domain ApbA_C PF08546.11 OAJ21030.1 - 2.5e-18 66.5 0.0 3e-16 59.8 0.0 2.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ21030.1 - 1e-16 61.0 0.9 2.1e-12 46.9 0.0 2.7 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 OAJ21030.1 - 0.028 15.0 0.0 4.1 8.0 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SSFA2_C PF14723.6 OAJ21030.1 - 0.11 12.4 0.4 0.23 11.3 0.4 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Gag_p15 PF08723.10 OAJ21030.1 - 0.15 12.3 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 Gag protein p15 Sin_N PF04801.13 OAJ21031.1 - 5e-20 72.1 0.0 2.2e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region Peptidase_S9_N PF02897.15 OAJ21032.1 - 1.4e-79 267.8 0.3 1.7e-79 267.5 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OAJ21032.1 - 1.2e-46 158.9 0.5 5e-46 156.9 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 OAJ21032.1 - 0.0087 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Adap_comp_sub PF00928.21 OAJ21033.1 - 3.9e-36 124.8 0.0 3.1e-35 121.8 0.0 2.2 1 1 0 1 1 1 1 Adaptor complexes medium subunit family RNase_PH PF01138.21 OAJ21034.1 - 1.4e-06 28.9 0.1 3.1e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ21034.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Peptidase_M20 PF01546.28 OAJ21034.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 TOM13 PF08219.11 OAJ21035.1 - 1.2e-09 38.0 1.8 2e-09 37.3 1.8 1.6 1 1 0 1 1 1 1 Outer membrane protein TOM13 PTPRCAP PF15713.5 OAJ21035.1 - 0.001 19.4 1.5 0.0015 18.9 1.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated LAT PF15234.6 OAJ21035.1 - 0.0051 16.6 1.0 0.0076 16.0 1.0 1.2 1 0 0 1 1 1 1 Linker for activation of T-cells NOA36 PF06524.12 OAJ21035.1 - 0.018 14.4 6.5 0.023 14.0 6.5 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 OAJ21035.1 - 0.02 15.3 12.3 0.034 14.5 12.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ21035.1 - 0.022 15.1 7.2 0.046 14.1 7.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 OAJ21035.1 - 0.029 14.1 7.7 0.036 13.8 7.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ21035.1 - 0.029 14.6 8.2 0.038 14.3 8.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 OAJ21035.1 - 0.12 12.2 1.9 0.16 11.7 1.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 OAJ21035.1 - 0.2 11.3 3.3 0.38 10.4 3.3 1.5 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 OAJ21035.1 - 0.32 9.2 5.2 0.38 8.9 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_YtfJ PF09579.10 OAJ21035.1 - 0.6 10.3 1.9 1.2 9.4 1.9 1.4 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) Astro_capsid_p PF12226.8 OAJ21035.1 - 0.73 8.9 5.6 0.94 8.6 5.6 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 OAJ21035.1 - 1.5 6.9 9.0 1.8 6.6 9.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi zf-Tim10_DDP PF02953.15 OAJ21036.1 - 2.4e-20 71.9 0.9 2.8e-20 71.7 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L7Ae PF01248.26 OAJ21037.1 - 2.7e-27 94.3 1.6 3.3e-27 94.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1353 PF07087.11 OAJ21037.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Cytochrom_B561 PF03188.16 OAJ21038.1 - 1e-10 41.9 11.7 1.7e-10 41.2 11.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 OAJ21038.1 - 0.25 11.5 19.1 0.2 11.8 16.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Claudin_3 PF06653.11 OAJ21038.1 - 0.34 10.8 5.3 2 8.4 5.3 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF202 PF02656.15 OAJ21038.1 - 0.69 10.4 13.9 1.3 9.5 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) 2OG-FeII_Oxy PF03171.20 OAJ21039.1 - 1.1e-11 45.1 0.1 7.5e-11 42.4 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAJ21039.1 - 9.1e-11 42.5 0.1 2e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RasGEF PF00617.19 OAJ21040.1 - 6e-57 192.7 0.3 1.2e-56 191.7 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ21040.1 - 8.5e-28 96.7 0.2 8.5e-28 96.7 0.2 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 OAJ21040.1 - 3.3e-13 49.0 0.1 8.7e-13 47.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ21040.1 - 6.7e-13 48.3 0.1 1.6e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ21040.1 - 2.1e-11 43.3 0.0 4.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 OAJ21040.1 - 8.8e-05 22.5 2.0 0.081 13.0 0.1 2.6 2 0 0 2 2 2 2 WW domain PQQ PF01011.21 OAJ21040.1 - 0.0073 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 PQQ enzyme repeat WD40 PF00400.32 OAJ21041.1 - 1.8e-14 53.9 0.1 0.008 17.0 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21041.1 - 2.5e-08 34.1 0.0 0.017 15.4 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 OAJ21041.1 - 0.1 11.2 0.0 9.8 4.7 0.0 2.6 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S13 PF00416.22 OAJ21042.1 - 2.5e-46 157.2 0.8 2.8e-46 157.1 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 OAJ21042.1 - 0.038 14.4 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) FbpA PF05833.11 OAJ21042.1 - 0.075 11.8 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) NAD_binding_7 PF13241.6 OAJ21043.1 - 3.1e-27 95.0 0.0 5.1e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ21043.1 - 1.1e-23 82.6 0.2 1.6e-23 82.1 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAJ21043.1 - 8.6e-13 47.5 0.9 2.3e-12 46.1 0.2 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Proteasome PF00227.26 OAJ21044.1 - 1.7e-32 112.4 0.0 2.1e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Bromodomain PF00439.25 OAJ21045.1 - 2.5e-17 62.7 0.1 6.3e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.20 OAJ21045.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 OAJ21045.1 - 0.00028 21.2 1.1 0.29 11.5 0.1 3.3 3 0 0 3 3 3 2 HEAT repeats Peptidase_M1_N PF17900.1 OAJ21045.1 - 0.056 13.6 1.0 0.59 10.3 0.0 2.6 3 0 0 3 3 3 0 Peptidase M1 N-terminal domain Glyco_hydro_31 PF01055.26 OAJ21046.1 - 4.5e-131 438.1 1.3 6e-131 437.6 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAJ21046.1 - 1.1e-22 80.1 0.2 2.4e-21 75.8 0.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAJ21046.1 - 9.2e-05 22.6 0.0 0.00061 20.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) TPR_1 PF00515.28 OAJ21047.1 - 1.8e-46 154.1 22.8 0.00011 21.9 0.2 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 OAJ21047.1 - 8.4e-35 118.5 18.5 2.2e-19 69.1 1.6 3.7 4 0 0 4 4 3 2 STI1 domain TPR_2 PF07719.17 OAJ21047.1 - 2.2e-34 114.8 21.8 0.0021 18.0 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21047.1 - 1.6e-22 77.8 21.0 0.00051 20.0 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ21047.1 - 1.5e-21 75.8 21.8 6.4e-05 22.6 0.3 8.6 7 2 1 8 8 8 6 TPR repeat TPR_12 PF13424.6 OAJ21047.1 - 9.1e-19 67.5 19.9 1.2e-09 38.3 1.1 6.8 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ21047.1 - 6.2e-17 60.9 12.7 0.2 12.6 0.0 9.6 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21047.1 - 7e-15 55.4 21.6 1.6e-05 25.5 0.6 7.6 3 3 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ21047.1 - 1.5e-11 43.8 3.0 0.077 13.4 0.1 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21047.1 - 2.3e-09 37.6 17.0 0.0017 18.8 0.2 6.7 4 3 3 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ21047.1 - 1.4e-07 31.6 5.8 0.02 15.0 0.3 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ21047.1 - 1.7e-06 27.6 9.5 0.012 15.6 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ21047.1 - 3e-06 26.9 17.1 2.3 8.2 0.1 8.7 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ21047.1 - 8.9e-05 22.9 13.4 7.5 7.4 0.0 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat DUF3808 PF10300.9 OAJ21047.1 - 0.0057 15.5 0.8 0.027 13.2 0.0 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3808) SR-25 PF10500.9 OAJ21047.1 - 0.022 14.4 5.9 0.052 13.1 5.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.8 OAJ21047.1 - 0.058 12.3 0.3 0.058 12.3 0.3 4.2 2 1 1 4 4 3 0 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 OAJ21047.1 - 0.31 11.3 15.2 0.071 13.3 1.8 4.1 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1826 PF08856.11 OAJ21047.1 - 5.3 6.9 6.0 0.6 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1826) XPC-binding PF09280.11 OAJ21047.1 - 8.4 6.2 7.8 1.7 8.4 1.3 3.1 3 0 0 3 3 3 0 XPC-binding domain RNase_PH PF01138.21 OAJ21048.1 - 1.3e-19 71.0 0.0 2.6e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ21048.1 - 1.2e-05 25.2 0.0 4.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF3889 PF13028.6 OAJ21048.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Shadoo PF14999.6 OAJ21048.1 - 0.041 14.0 3.1 0.058 13.5 2.4 1.5 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3168 PF11367.8 OAJ21048.1 - 0.12 12.6 2.6 12 6.1 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3168) Hexapep PF00132.24 OAJ21049.1 - 1.7e-07 30.7 12.9 0.018 14.8 1.0 4.0 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ21049.1 - 2.1e-05 24.1 9.7 0.0024 17.6 2.9 3.4 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Ku PF02735.16 OAJ21050.1 - 1.1e-28 100.4 0.1 8.4e-28 97.5 0.0 2.6 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 OAJ21050.1 - 2.9e-17 62.9 1.0 8.4e-17 61.4 0.0 2.4 3 0 0 3 3 3 1 Ku C terminal domain like DUF600 PF04634.12 OAJ21050.1 - 0.038 14.0 0.1 0.074 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 gpW PF02831.15 OAJ21050.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 gpW DNA_pol_phi PF04931.13 OAJ21050.1 - 6.7 4.7 13.2 11 4.0 13.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi COX5B PF01215.19 OAJ21051.1 - 3.9e-46 155.9 0.0 4.8e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 OAJ21051.1 - 0.00061 19.8 0.2 0.00093 19.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_3 PF13878.6 OAJ21051.1 - 0.0062 16.3 1.5 0.0099 15.7 1.5 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zinc_ribbon_4 PF13717.6 OAJ21051.1 - 0.19 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MIF4G PF02854.19 OAJ21052.1 - 8.7e-16 58.2 0.0 1.5e-14 54.2 0.0 2.3 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OAJ21052.1 - 1.6e-11 44.1 0.0 4.2e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 MA3 domain ECH_1 PF00378.20 OAJ21053.1 - 9.2e-17 61.2 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ21053.1 - 2.7e-05 23.8 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MTHFR PF02219.17 OAJ21054.1 - 4.1e-95 318.4 0.0 4.9e-84 282.1 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase TcA_TcB_BD PF18276.1 OAJ21054.1 - 0.084 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Mito_carr PF00153.27 OAJ21055.1 - 4.7e-63 209.2 2.9 5.5e-24 83.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_ATPase PF13246.6 OAJ21055.1 - 0.2 11.8 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) WD40 PF00400.32 OAJ21056.1 - 2.5e-18 66.1 7.6 0.00036 21.3 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21056.1 - 0.0011 19.3 0.1 32 4.9 0.0 4.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 OAJ21057.1 - 7.1e-63 208.6 4.2 3.9e-21 74.8 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF5331 PF17265.2 OAJ21057.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Phage_holin_2_4 PF16082.5 OAJ21057.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ribosomal_S17_N PF16205.5 OAJ21058.1 - 3.8e-30 104.1 0.1 8.2e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAJ21058.1 - 6.8e-27 93.4 0.3 6.8e-27 93.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Mito_carr PF00153.27 OAJ21059.1 - 1.5e-32 111.3 7.9 8.9e-14 51.2 0.1 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 OAJ21060.1 - 1.1e-15 57.2 0.0 1.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ21060.1 - 3e-06 26.9 0.0 3.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MoaE PF02391.17 OAJ21061.1 - 1.9e-35 121.5 0.0 2.7e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 MoaE protein CAP_N PF01213.19 OAJ21061.1 - 0.19 11.2 1.1 0.26 10.8 1.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 OAJ21061.1 - 3.4 8.1 9.1 1.6 9.2 4.3 2.5 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein QCR10 PF09796.9 OAJ21062.1 - 1e-14 54.3 0.9 1.5e-14 53.8 0.9 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 OAJ21062.1 - 0.077 13.0 0.3 0.16 12.0 0.3 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF1295 PF06966.12 OAJ21063.1 - 2.8e-43 148.2 0.0 7.2e-43 146.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAJ21063.1 - 0.029 14.8 0.0 0.1 13.0 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 OAJ21063.1 - 0.032 14.2 0.0 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Acyl-CoA_dh_N PF02771.16 OAJ21063.1 - 0.038 14.6 0.1 0.087 13.5 0.1 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Chorismate_synt PF01264.21 OAJ21064.1 - 8.7e-138 458.5 0.1 1e-137 458.3 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase EMP24_GP25L PF01105.24 OAJ21086.1 - 1.7e-50 171.5 0.0 2.1e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAJ21086.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Ras PF00071.22 OAJ21087.1 - 9.2e-51 171.7 0.1 1.1e-50 171.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ21087.1 - 9.8e-31 106.5 0.0 1.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ21087.1 - 1.2e-11 44.3 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ21087.1 - 0.00023 20.6 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ21087.1 - 0.00031 20.0 0.1 0.068 12.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ21087.1 - 0.0041 17.2 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAJ21087.1 - 0.019 15.3 0.4 0.67 10.4 0.4 2.2 1 1 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 OAJ21087.1 - 0.051 13.1 0.6 0.21 11.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 OAJ21087.1 - 0.06 12.8 0.1 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 OAJ21087.1 - 0.063 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ21087.1 - 0.093 12.2 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAJ21087.1 - 0.094 12.6 0.1 12 5.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 OAJ21087.1 - 0.1 11.8 0.3 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 Septin TsaE PF02367.17 OAJ21087.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 OAJ21087.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Nic96 PF04097.14 OAJ21088.1 - 7.1e-169 563.2 0.0 9e-169 562.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Voltage_CLC PF00654.20 OAJ21089.1 - 1.7e-90 303.8 29.7 3.1e-90 303.0 29.7 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OAJ21089.1 - 7.5e-12 45.5 0.0 5.7e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain bZIP_1 PF00170.21 OAJ21090.1 - 0.00012 22.1 13.6 0.00025 21.1 12.7 2.0 1 1 1 2 2 2 1 bZIP transcription factor TPPK_C PF12555.8 OAJ21090.1 - 0.62 10.2 4.7 0.57 10.3 0.2 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal HNOBA PF07701.14 OAJ21090.1 - 1.1 8.7 7.4 1.3 8.4 0.3 2.3 2 0 0 2 2 2 0 Heme NO binding associated RAB3GAP2_N PF14655.6 OAJ21090.1 - 2 7.6 7.4 3.3 6.9 7.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SLATT_1 PF18181.1 OAJ21090.1 - 6.6 6.7 17.2 1.7 8.6 1.4 3.0 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 OrsD PF12013.8 OAJ21091.1 - 1.2e-06 29.0 0.5 0.00016 22.1 0.1 2.5 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D Aminotran_1_2 PF00155.21 OAJ21092.1 - 4.2e-35 121.6 0.0 5.2e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ21092.1 - 0.053 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ21093.1 - 7.2e-34 117.5 0.0 8.4e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ21093.1 - 0.03 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pyr_redox_2 PF07992.14 OAJ21094.1 - 2.1e-43 148.7 0.9 5e-41 140.9 0.5 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ21094.1 - 3.1e-19 69.0 0.0 6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ21094.1 - 9.9e-17 61.3 6.5 1.9e-13 50.8 0.7 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 OAJ21094.1 - 3.2e-16 59.4 5.8 2.6e-10 40.5 5.7 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.6 OAJ21094.1 - 7e-15 54.8 0.0 2.6e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAJ21094.1 - 8.1e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 OAJ21094.1 - 3.8e-11 42.8 0.1 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.6 OAJ21094.1 - 1.5e-05 25.0 5.8 0.41 10.6 0.0 3.9 3 1 1 4 4 4 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ21094.1 - 1.6e-05 24.3 0.1 1.2 8.3 0.0 4.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 OAJ21094.1 - 0.00012 21.9 0.2 0.16 12.0 0.0 2.9 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain DAO PF01266.24 OAJ21094.1 - 0.0012 18.5 5.4 0.34 10.4 0.1 4.2 3 1 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ21094.1 - 0.0016 17.7 0.1 0.54 9.3 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAJ21094.1 - 0.0066 15.6 4.9 0.49 9.4 0.2 3.0 1 1 1 2 2 2 2 FAD binding domain TrkA_N PF02254.18 OAJ21094.1 - 0.016 15.4 1.9 1.8 8.8 0.3 2.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_8 PF13450.6 OAJ21094.1 - 1.9 8.7 3.6 1.3 9.3 0.1 2.5 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAJ21094.1 - 2.4 7.2 4.9 14 4.6 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A PAC2 PF09754.9 OAJ21095.1 - 2.2e-24 86.7 0.1 3e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 PAC2 family zf-HC5HC2H_2 PF13832.6 OAJ21097.1 - 6e-19 68.2 1.2 6e-19 68.2 1.2 4.2 4 1 1 5 5 5 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAJ21097.1 - 2e-15 56.8 1.0 2e-15 56.8 1.0 4.3 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 OAJ21097.1 - 4.2e-12 45.8 25.2 4.4e-09 36.1 6.9 5.1 7 0 0 7 7 7 3 PHD-finger BAH PF01426.18 OAJ21097.1 - 2.4e-08 33.8 0.1 8.2e-08 32.1 0.0 1.9 3 0 0 3 3 3 1 BAH domain GATA PF00320.27 OAJ21097.1 - 1.2e-05 24.8 3.0 1.2e-05 24.8 3.0 4.1 5 0 0 5 5 5 1 GATA zinc finger PHD_2 PF13831.6 OAJ21097.1 - 0.00037 20.0 5.6 0.00037 20.0 5.6 5.4 5 0 0 5 5 5 2 PHD-finger Myb_DNA-bind_7 PF15963.5 OAJ21097.1 - 0.0033 17.3 0.2 0.01 15.7 0.2 1.8 1 0 0 1 1 1 1 Myb DNA-binding like ELM2 PF01448.24 OAJ21097.1 - 0.042 14.6 0.9 0.12 13.2 0.1 2.2 2 0 0 2 2 2 0 ELM2 domain DUF498 PF04430.14 OAJ21098.1 - 1.1e-25 89.8 0.0 3.1e-25 88.4 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Cyclin PF08613.11 OAJ21099.1 - 6.3e-10 39.7 0.0 2.6e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ21099.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain ANAPC4_WD40 PF12894.7 OAJ21100.1 - 7.6e-07 29.3 0.0 0.025 14.9 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ21100.1 - 2.5e-05 25.0 1.4 0.026 15.4 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat bZIP_1 PF00170.21 OAJ21101.1 - 4.9e-05 23.3 8.8 0.00012 22.1 8.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ21101.1 - 0.00086 19.3 7.4 0.0019 18.2 7.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 OAJ21101.1 - 0.38 11.3 8.9 0.86 10.2 8.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor RasGAP PF00616.19 OAJ21102.1 - 9.5e-20 71.2 0.0 1.2e-12 48.0 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 OAJ21102.1 - 5.4e-09 36.3 0.0 3.6e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 OAJ21102.1 - 0.00036 20.5 0.2 0.0057 16.5 0.0 3.0 3 0 0 3 3 3 1 Cell morphogenesis C-terminal CHCH PF06747.13 OAJ21103.1 - 1.3e-06 28.3 5.4 2.1e-06 27.7 5.4 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAJ21103.1 - 0.0061 16.5 2.3 0.0093 16.0 2.3 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ21103.1 - 0.034 14.4 5.1 0.28 11.5 5.1 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 OAJ21103.1 - 0.081 13.2 0.9 0.13 12.5 0.9 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.13 OAJ21103.1 - 0.18 12.1 4.8 0.83 10.1 0.7 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 OAJ21103.1 - 0.23 11.7 2.5 3 8.2 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) SR-25 PF10500.9 OAJ21103.1 - 0.27 10.8 3.7 0.29 10.7 3.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cmc1 PF08583.10 OAJ21103.1 - 0.46 10.5 5.6 1.1 9.3 5.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Thioredoxin PF00085.20 OAJ21106.1 - 2.9e-20 72.2 0.0 3.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ21106.1 - 4.6e-06 27.0 0.1 1.6e-05 25.3 0.0 1.9 2 1 0 2 2 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ21106.1 - 2.2e-05 24.4 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAJ21106.1 - 0.00057 20.2 0.0 0.034 14.5 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like KaiB PF07689.12 OAJ21106.1 - 0.0014 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_7 PF13899.6 OAJ21106.1 - 0.0065 16.6 0.1 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 OAJ21106.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin DUF953 PF06110.11 OAJ21106.1 - 0.016 14.8 0.1 0.059 13.0 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 OAJ21106.1 - 0.017 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 OAJ21106.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 OAJ21106.1 - 0.031 14.2 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DIM1 PF02966.16 OAJ21106.1 - 0.041 13.7 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF836 PF05768.14 OAJ21106.1 - 0.052 14.0 0.0 0.079 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Aminotran_4 PF01063.19 OAJ21107.1 - 1.4e-24 87.2 0.0 3.3e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV tRNA_U5-meth_tr PF05958.11 OAJ21108.1 - 2.5e-17 62.9 0.0 4.1e-16 58.9 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 OAJ21108.1 - 2.6e-06 27.3 0.8 5.7e-06 26.2 0.8 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.10 OAJ21108.1 - 1.6e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OAJ21108.1 - 2.1e-05 25.1 0.0 0.0001 23.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21108.1 - 4e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ21108.1 - 0.00044 19.8 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 OAJ21108.1 - 0.0012 19.4 0.0 0.0031 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ21108.1 - 0.017 14.5 0.2 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 OAJ21108.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF5334 PF17268.2 OAJ21108.1 - 0.043 14.1 0.4 0.14 12.5 0.4 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5334) Met_10 PF02475.16 OAJ21108.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein SpoIIIAH PF12685.7 OAJ21108.1 - 2.5 7.9 6.9 6.6 6.5 6.9 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein Oxidored_molyb PF00174.19 OAJ21109.1 - 1.5e-50 171.2 0.0 2.6e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAJ21109.1 - 2.8e-43 147.3 0.3 5.5e-43 146.3 0.3 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 OAJ21109.1 - 8.1e-26 90.3 0.0 1.7e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ21109.1 - 5e-22 78.6 0.0 1.6e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAJ21109.1 - 1.8e-19 69.7 0.0 3.6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAJ21109.1 - 0.0014 18.7 0.1 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF1073 PF06381.11 OAJ21109.1 - 0.006 15.4 0.0 0.017 14.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1073) Polbeta PF18765.1 OAJ21109.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase MFS_1 PF07690.16 OAJ21110.1 - 9.9e-30 103.6 27.5 1.7e-29 102.9 27.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.21 OAJ21111.1 - 1.1e-62 211.5 0.0 2.5e-62 210.3 0.0 1.7 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ21111.1 - 2.1e-33 116.2 6.8 7.2e-33 114.4 6.8 1.9 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ21111.1 - 3.7e-18 65.8 0.0 8.3e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ21111.1 - 2.3e-09 37.6 0.0 1.6e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 OAJ21111.1 - 0.0011 18.6 0.0 0.0035 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ21111.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ21111.1 - 1.7 9.1 0.0 1.7 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain Oxysterol_BP PF01237.18 OAJ21112.1 - 6.8e-85 285.1 1.4 9.5e-83 278.1 1.4 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein TPR_1 PF00515.28 OAJ21114.1 - 6e-54 177.8 19.1 4.1e-07 29.5 0.0 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ21114.1 - 1.5e-49 162.2 16.1 5.3e-06 26.1 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21114.1 - 1.2e-36 121.8 10.4 9.7e-05 22.3 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ21114.1 - 1.3e-28 97.3 14.3 0.00082 19.6 0.1 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ21114.1 - 1.8e-28 97.9 24.1 7e-07 28.8 0.1 9.4 4 2 5 9 9 9 6 TPR repeat TPR_14 PF13428.6 OAJ21114.1 - 1.1e-24 85.0 19.6 0.0021 18.7 0.0 9.6 4 2 6 10 10 9 8 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21114.1 - 2.9e-24 85.3 14.6 1e-05 26.0 0.1 7.0 4 2 4 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ21114.1 - 1.3e-23 81.3 6.6 0.0084 16.1 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21114.1 - 3.5e-23 82.0 20.3 2.8e-06 27.8 0.0 7.8 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ21114.1 - 3.5e-23 81.7 10.4 0.0001 22.5 0.1 6.9 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ21114.1 - 2.1e-15 56.6 10.4 0.0019 18.3 0.3 7.5 2 1 8 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ21114.1 - 1e-14 54.5 5.6 2.3e-07 30.9 0.3 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAJ21114.1 - 2.6e-14 52.8 21.2 0.011 16.3 0.0 9.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ21114.1 - 3.8e-06 26.5 0.2 0.0057 16.1 0.2 2.7 2 0 0 2 2 2 2 MalT-like TPR region TPR_15 PF13429.6 OAJ21114.1 - 8.4e-06 25.2 9.0 0.065 12.4 0.4 5.3 1 1 4 5 5 5 3 Tetratricopeptide repeat DUF4919 PF16266.5 OAJ21114.1 - 6.9e-05 22.9 0.3 0.011 15.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_10 PF13374.6 OAJ21114.1 - 0.0008 19.2 18.3 0.45 10.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ21114.1 - 0.084 13.2 0.0 0.084 13.2 0.0 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat ChAPs PF09295.10 OAJ21114.1 - 0.098 11.6 1.2 6.6 5.6 0.2 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.12 OAJ21114.1 - 2.7 8.1 12.4 6.3 6.9 0.6 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 OAJ21114.1 - 3.7 8.0 16.3 1.4 9.3 1.6 4.2 3 2 1 4 4 3 0 Bacterial transcriptional activator domain SKN1 PF03935.15 OAJ21115.1 - 1.7e-184 613.9 2.6 2.1e-184 613.6 2.6 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3824 PF12868.7 OAJ21133.1 - 0.00029 21.5 1.9 0.00035 21.3 1.9 1.1 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) EP400_N PF15790.5 OAJ21133.1 - 0.028 13.3 0.7 0.03 13.2 0.7 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal LtrA PF06772.11 OAJ21134.1 - 7.6e-37 127.3 21.3 1e-36 126.9 21.3 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) NPL4 PF05021.15 OAJ21135.1 - 7.3e-90 301.4 0.0 8.6e-88 294.6 0.0 3.1 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.15 OAJ21135.1 - 1.7e-66 222.9 0.1 2.6e-66 222.2 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAJ21135.1 - 0.00012 22.5 0.0 0.00031 21.2 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 OAJ21135.1 - 0.0018 17.6 1.3 0.0018 17.6 1.3 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others UIM PF02809.20 OAJ21135.1 - 0.0034 17.2 0.6 0.016 15.1 0.6 2.3 1 0 0 1 1 1 1 Ubiquitin interaction motif DZR PF12773.7 OAJ21135.1 - 1.9 8.6 5.1 0.53 10.3 0.2 2.5 3 0 0 3 3 3 0 Double zinc ribbon MMR_HSR1 PF01926.23 OAJ21136.1 - 1.9e-12 47.3 0.0 8e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ21136.1 - 0.0005 19.6 0.1 0.001 18.6 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ21136.1 - 0.0011 19.1 0.1 0.0035 17.4 0.1 1.9 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 OAJ21136.1 - 0.017 15.0 0.0 0.18 11.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 OAJ21136.1 - 0.22 10.8 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family WD40 PF00400.32 OAJ21137.1 - 4.1e-41 138.2 18.2 7.7e-07 29.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21137.1 - 8.4e-14 51.6 0.1 0.00096 19.4 0.1 4.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAJ21137.1 - 0.022 14.1 0.0 0.1 11.9 0.0 2.1 1 1 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 OAJ21137.1 - 0.15 11.0 1.0 40 3.0 0.0 3.5 2 1 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein adh_short PF00106.25 OAJ21138.1 - 6.6e-26 91.0 0.0 8.9e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ21138.1 - 7e-17 61.8 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ21138.1 - 0.0037 17.2 1.6 0.042 13.8 1.6 2.2 1 1 0 1 1 1 1 KR domain CAF1C_H4-bd PF12265.8 OAJ21139.1 - 2.7e-17 62.8 0.3 8.7e-17 61.1 0.0 2.1 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ21139.1 - 7.9e-13 48.7 4.4 2.8e-05 24.8 0.1 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21139.1 - 0.0026 18.0 0.2 0.11 12.8 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 OAJ21139.1 - 0.25 9.9 28.6 0.11 11.0 19.9 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GARS_A PF01071.19 OAJ21140.1 - 6.6e-69 231.6 0.0 9.8e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 OAJ21140.1 - 5.1e-29 100.9 0.0 1.7e-28 99.2 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 OAJ21140.1 - 7.9e-28 97.6 0.0 1.6e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 OAJ21140.1 - 4e-27 94.3 0.2 1e-26 93.0 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OAJ21140.1 - 1.1e-12 48.4 1.7 3.3e-12 46.9 1.7 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain BRCA2 PF00634.18 OAJ21140.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 BRCA2 repeat Pkr1 PF08636.10 OAJ21143.1 - 4.3e-25 87.6 2.1 5.1e-25 87.4 2.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2784 PF10861.8 OAJ21143.1 - 0.78 9.8 4.3 3.1 7.8 2.5 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF2784) Ribosomal_L1 PF00687.21 OAJ21145.1 - 7.7e-23 81.3 0.0 1.4e-21 77.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family TP_methylase PF00590.20 OAJ21145.1 - 0.005 16.8 1.5 0.012 15.6 0.3 2.1 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Haspin_kinase PF12330.8 OAJ21146.1 - 1.9e-50 171.8 0.0 9.3e-50 169.6 0.0 2.0 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 OAJ21146.1 - 0.013 15.4 0.1 0.037 13.9 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5343 PF17278.2 OAJ21146.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) NOA36 PF06524.12 OAJ21146.1 - 1.1 8.5 5.7 2.6 7.3 5.7 1.5 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpb2_6 PF00562.28 OAJ21147.1 - 6e-122 407.5 0.2 5e-118 394.6 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ21147.1 - 1e-61 208.0 0.0 1.6e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ21147.1 - 5.2e-47 159.9 0.0 9.8e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ21147.1 - 6.9e-32 109.7 0.3 2.3e-31 108.0 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAJ21147.1 - 1.2e-25 89.4 0.1 3e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OAJ21147.1 - 2.2e-23 82.3 0.0 6.1e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OAJ21147.1 - 3e-19 69.3 0.0 7.4e-19 68.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.8 OAJ21148.1 - 3.1e-25 89.0 0.8 3.1e-25 89.0 0.8 3.7 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAJ21148.1 - 4.5e-14 52.3 12.2 4.5e-14 52.3 12.2 4.4 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR NARP1 PF12569.8 OAJ21149.1 - 2.6e-153 511.7 8.8 2.6e-153 511.7 8.8 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OAJ21149.1 - 6.3e-15 54.0 14.4 1.9e-05 24.4 0.0 9.3 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ21149.1 - 1.4e-10 40.5 4.3 4.1e-05 23.2 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21149.1 - 1.1e-09 38.6 35.7 0.0035 17.8 0.0 9.7 8 2 2 10 10 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ21149.1 - 1.6e-09 37.8 30.5 0.28 12.1 0.0 10.2 9 2 1 10 10 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ21149.1 - 1.6e-09 37.1 9.5 0.0019 18.1 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ21149.1 - 8.2e-08 32.3 10.2 0.00087 19.4 0.2 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21149.1 - 1.2e-06 28.2 4.2 0.39 11.1 0.1 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ21149.1 - 2e-06 27.7 0.3 4.1 8.0 0.0 7.4 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ21149.1 - 0.0012 19.1 19.4 0.024 14.9 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ21149.1 - 0.0032 17.1 2.2 2.1 8.1 0.0 4.7 5 0 0 5 5 5 1 TPR repeat Ins_allergen_rp PF06757.13 OAJ21149.1 - 0.042 13.8 1.7 0.2 11.6 0.0 2.8 3 1 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification TPR_6 PF13174.6 OAJ21149.1 - 0.096 13.4 19.9 0.27 12.0 0.1 8.6 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21149.1 - 0.1 13.2 0.1 0.1 13.2 0.1 10.2 10 1 1 11 11 9 0 Tetratricopeptide repeat DDE_Tnp_ISL3 PF01610.17 OAJ21149.1 - 0.43 10.2 3.8 0.53 10.0 1.5 2.4 2 0 0 2 2 2 0 Transposase TPR_10 PF13374.6 OAJ21149.1 - 0.8 9.7 10.1 11 6.0 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TAF4 PF05236.14 OAJ21149.1 - 7.5 6.2 15.2 0.074 12.8 7.2 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family AMP-binding PF00501.28 OAJ21150.1 - 1.2e-95 320.7 0.0 1.4e-95 320.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ21150.1 - 3.9e-10 40.6 0.3 1e-09 39.2 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MMM1 PF10296.9 OAJ21151.1 - 0.00029 20.0 0.0 0.00099 18.3 0.0 1.8 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Pkinase PF00069.25 OAJ21152.1 - 2.1e-27 96.2 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21152.1 - 5e-16 58.8 0.0 7.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ21152.1 - 1.2e-09 37.5 1.5 1.7e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ21152.1 - 0.0003 20.8 1.1 0.0082 16.1 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ21152.1 - 0.041 12.9 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAJ21152.1 - 0.045 13.1 0.5 0.14 11.5 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 4HBT_2 PF13279.6 OAJ21153.1 - 2e-09 38.0 0.0 2.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily zf-CCCH PF00642.24 OAJ21154.1 - 2.2e-23 81.6 33.1 1e-06 28.5 0.3 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ21154.1 - 8.4e-21 73.3 34.7 3.6e-06 26.8 3.0 5.5 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAJ21154.1 - 1.1e-11 45.4 24.1 0.00017 22.3 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAJ21154.1 - 2.8e-06 27.0 0.8 2.8e-06 27.0 0.8 5.2 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCHC PF00098.23 OAJ21154.1 - 3.1e-06 27.0 0.9 3.1e-06 27.0 0.9 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_3 PF15663.5 OAJ21154.1 - 0.0001 22.5 12.1 0.0032 17.7 0.1 3.6 1 1 3 4 4 4 2 Zinc-finger containing family zf-CCHC_3 PF13917.6 OAJ21154.1 - 0.098 12.6 4.2 0.16 11.9 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCCH_2 PF14608.6 OAJ21154.1 - 3.3 8.3 45.4 0.078 13.5 1.9 5.8 6 0 0 6 6 6 0 RNA-binding, Nab2-type zinc finger SLS PF14611.6 OAJ21155.1 - 0.0077 16.1 0.2 0.79 9.5 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial inner-membrane-bound regulator DUF4058 PF13267.6 OAJ21155.1 - 0.051 13.0 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Glyco_hydro_3 PF00933.21 OAJ21156.1 - 9.2e-69 232.2 3.3 1.8e-68 231.3 1.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAJ21156.1 - 0.2 11.6 3.5 0.28 11.1 0.1 2.7 3 1 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain Pkinase PF00069.25 OAJ21158.1 - 1.8e-64 217.7 0.0 2.5e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21158.1 - 1.7e-28 99.6 0.0 2.4e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ21158.1 - 4.2e-15 56.2 2.2 6.8e-15 55.5 0.6 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 OAJ21158.1 - 2.2e-08 34.3 0.2 0.00014 22.1 0.1 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 OAJ21158.1 - 3.5e-08 33.1 0.0 7.8e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 OAJ21158.1 - 0.004 16.1 0.1 0.0075 15.3 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 OAJ21158.1 - 0.0087 15.7 0.1 0.78 9.3 0.1 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAJ21158.1 - 0.04 13.8 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CtnDOT_TraJ PF07863.11 OAJ21159.1 - 0.0088 16.7 3.4 0.0088 16.7 3.4 3.5 4 0 0 4 4 4 1 Homologues of TraJ from Bacteroides conjugative transposon zf-C2H2_4 PF13894.6 OAJ21159.1 - 0.075 13.9 1.1 0.2 12.6 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Ish1 PF10281.9 OAJ21160.1 - 1.7e-60 201.0 26.6 4e-13 49.4 0.3 6.7 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 OAJ21160.1 - 0.00028 20.6 0.0 1.3 8.8 0.0 4.3 4 0 0 4 4 4 1 SAP domain Apolipoprotein PF01442.18 OAJ21160.1 - 0.0081 16.0 12.0 0.1 12.4 1.4 3.4 2 2 1 3 3 3 3 Apolipoprotein A1/A4/E domain LEM PF03020.15 OAJ21160.1 - 0.017 14.6 0.0 57 3.4 0.0 4.4 5 0 0 5 5 5 0 LEM domain DEP PF00610.21 OAJ21160.1 - 0.14 12.3 0.5 11 6.2 0.1 3.8 5 0 0 5 5 5 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RRM_1 PF00076.22 OAJ21161.1 - 9.6e-19 67.0 0.1 3.3e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ21161.1 - 3.3e-10 39.6 0.0 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ21161.1 - 0.013 15.4 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Mpp10 PF04006.12 OAJ21161.1 - 0.23 9.9 7.5 0.32 9.4 7.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Homeobox_KN PF05920.11 OAJ21162.1 - 1.3e-07 31.4 0.0 6.2e-07 29.2 0.0 2.3 1 1 0 1 1 1 1 Homeobox KN domain PBP1_TM PF14812.6 OAJ21162.1 - 0.13 12.7 1.6 0.29 11.5 1.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Homeodomain PF00046.29 OAJ21163.1 - 5.2e-15 55.0 1.0 1.2e-14 53.9 1.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAJ21163.1 - 0.00012 21.9 0.6 0.00026 20.8 0.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain Sigma70_ner PF04546.13 OAJ21163.1 - 1.3 8.8 9.0 0.033 14.1 2.0 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Pescadillo_N PF06732.11 OAJ21164.1 - 5.5e-120 400.0 0.0 1.1e-119 399.0 0.0 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAJ21164.1 - 1.9e-07 31.4 0.0 5.1e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ21164.1 - 5.2e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ21164.1 - 0.017 15.4 0.0 0.065 13.5 0.0 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Ribosomal_S13_N PF08069.12 OAJ21165.1 - 0.061 13.4 0.4 14 5.8 0.4 2.6 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain MMR_HSR1_Xtn PF16897.5 OAJ21166.1 - 1.2e-41 141.0 0.1 2.5e-41 140.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 OAJ21166.1 - 1.2e-20 73.7 0.0 3.3e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 OAJ21166.1 - 1.8e-20 72.7 0.1 3.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 OAJ21166.1 - 1.1e-10 41.3 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ21166.1 - 0.00073 19.6 0.2 0.029 14.4 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 OAJ21166.1 - 0.003 17.9 0.9 0.13 12.6 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 OAJ21166.1 - 0.053 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain DUF1002 PF06207.11 OAJ21166.1 - 0.06 12.9 0.6 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Ipi1_N PF12333.8 OAJ21167.1 - 4.1e-15 56.2 0.0 6.4e-13 49.2 0.0 3.6 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation PBP1_TM PF14812.6 OAJ21167.1 - 0.0045 17.3 1.6 0.011 16.1 1.6 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ21167.1 - 0.011 16.2 1.0 0.02 15.3 1.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 OAJ21167.1 - 2.6 7.6 4.6 3.1 7.3 2.4 2.2 2 1 1 3 3 3 0 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 OAJ21167.1 - 5.8 4.9 8.2 9.5 4.2 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sec3_C PF09763.9 OAJ21168.1 - 4.1e-85 286.6 0.0 6.1e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAJ21168.1 - 3.2e-18 65.6 0.0 5.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAJ21168.1 - 0.0023 16.8 0.3 0.0034 16.2 0.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Acetyltransf_1 PF00583.25 OAJ21169.1 - 4.9e-15 55.8 0.0 8.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ21169.1 - 3.4e-10 39.9 0.0 5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ21169.1 - 9.3e-10 38.8 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ21169.1 - 7.3e-09 35.5 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OAJ21169.1 - 9e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ21169.1 - 2.9e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ21169.1 - 3.4e-06 27.8 0.0 6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAJ21169.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAJ21169.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CtaG_Cox11 PF04442.14 OAJ21170.1 - 8.3e-56 188.2 0.0 1.2e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 UPF0121 PF03661.13 OAJ21193.1 - 1.1e-38 133.0 7.1 1.4e-38 132.7 7.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DeoC PF01791.9 OAJ21194.1 - 2.8e-11 43.5 1.1 5.5e-11 42.5 1.1 1.4 1 1 0 1 1 1 1 DeoC/LacD family aldolase ADP_ribosyl_GH PF03747.14 OAJ21194.1 - 0.00078 19.3 3.7 0.0013 18.6 3.7 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase MqsR_toxin PF15723.5 OAJ21194.1 - 0.16 12.4 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Zip PF02535.22 OAJ21195.1 - 1.3e-11 44.4 0.1 1.5e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter PMT PF02366.18 OAJ21197.1 - 3e-73 246.4 18.3 4.9e-73 245.7 18.3 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ21197.1 - 2.1e-52 177.6 6.9 5.7e-52 176.2 6.9 1.8 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ21197.1 - 8.2e-26 91.0 0.1 1.4e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 MIR domain Septin PF00735.18 OAJ21198.1 - 1.2e-16 60.8 0.0 1.8e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Septin Zip PF02535.22 OAJ21198.1 - 0.00057 19.2 3.6 0.0038 16.5 3.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 OAJ21200.1 - 2.6e-13 49.9 2.6 2.8e-13 49.8 2.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter FliC PF12445.8 OAJ21201.1 - 0.011 16.0 1.0 0.019 15.3 1.0 1.4 1 0 0 1 1 1 0 Flagellin protein Fungal_trans PF04082.18 OAJ21203.1 - 3.3e-28 98.4 0.0 5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ21203.1 - 4e-09 36.4 6.3 7.2e-09 35.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fibrillarin PF01269.17 OAJ21204.1 - 3.1e-104 347.0 0.0 3.9e-104 346.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAJ21204.1 - 3.2e-05 23.7 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 OAJ21204.1 - 0.004 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 OAJ21204.1 - 0.004 17.3 0.0 0.0051 16.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 OAJ21204.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Period_C PF12114.8 OAJ21205.1 - 0.073 12.7 6.3 0.13 11.8 6.3 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.9 OAJ21205.1 - 0.21 10.1 3.2 0.25 9.8 3.2 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 OAJ21205.1 - 0.6 9.7 15.7 1.3 8.6 15.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 OAJ21205.1 - 1.2 8.9 6.1 2.5 7.9 5.8 1.6 2 0 0 2 2 2 0 SPX domain Pex14_N PF04695.13 OAJ21205.1 - 1.6 9.3 10.8 0.12 13.0 2.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AF-4 PF05110.13 OAJ21205.1 - 9.3 4.2 18.2 14 3.5 18.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sulfate_transp PF00916.20 OAJ21206.1 - 5.5e-112 374.3 16.9 7.2e-112 373.9 16.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAJ21206.1 - 2.3e-10 40.1 0.0 4.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAJ21206.1 - 0.029 14.8 20.5 0.045 14.2 4.2 3.3 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Ribosomal_L35Ae PF01247.18 OAJ21207.1 - 1.1e-39 134.5 0.2 1.2e-39 134.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAJ21207.1 - 0.029 14.6 0.1 2.6 8.3 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain IPPT PF01715.17 OAJ21208.1 - 1e-52 179.2 0.4 2.1e-51 175.0 0.4 2.2 1 1 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 OAJ21208.1 - 0.0074 16.6 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAJ21208.1 - 0.043 13.6 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein IPT PF01745.16 OAJ21208.1 - 0.05 13.0 0.5 0.24 10.7 0.5 2.0 1 1 0 1 1 1 0 Isopentenyl transferase PhoH PF02562.16 OAJ21208.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 OAJ21208.1 - 0.072 13.5 0.5 0.25 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 OAJ21208.1 - 0.087 13.4 0.1 0.087 13.4 0.1 3.3 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 OAJ21208.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 OAJ21208.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.5 4 1 0 4 4 4 0 AAA domain Aminotran_5 PF00266.19 OAJ21209.1 - 6.4e-34 117.5 0.0 1.4e-33 116.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V hDGE_amylase PF14701.6 OAJ21210.1 - 2.4e-164 547.6 0.0 3.3e-164 547.2 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAJ21210.1 - 1.5e-110 369.8 0.0 2e-110 369.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OAJ21210.1 - 3.2e-83 279.3 0.0 5.1e-83 278.6 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAJ21210.1 - 3.1e-18 65.7 0.0 6.4e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAJ21210.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF423 PF04241.15 OAJ21211.1 - 1.8e-25 88.9 1.4 3e-25 88.3 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2627 PF11118.8 OAJ21211.1 - 0.24 12.0 1.0 2.2 8.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) NmrA PF05368.13 OAJ21212.1 - 8.1e-16 58.3 0.0 1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ21212.1 - 5.8e-09 36.1 0.0 8.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 OAJ21212.1 - 0.01 16.4 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAJ21212.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 OAJ21212.1 - 0.16 12.2 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.18 OAJ21213.1 - 1.1e-22 80.3 0.0 4e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ21213.1 - 2.6e-09 37.1 6.8 4e-09 36.4 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_28 PF03033.20 OAJ21214.1 - 2.4e-32 111.9 0.0 5.6e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ21214.1 - 2.6e-09 37.0 0.0 0.0029 17.5 0.0 3.6 4 0 0 4 4 4 3 GRAM domain UDPGT PF00201.18 OAJ21214.1 - 0.003 16.4 0.0 0.0084 14.9 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_17 PF18012.1 OAJ21214.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 PH domain PH PF00169.29 OAJ21214.1 - 0.072 13.6 0.0 0.3 11.6 0.0 2.1 2 1 0 2 2 2 0 PH domain Abhydrolase_4 PF08386.10 OAJ21216.1 - 4.8e-15 55.5 0.0 1.5e-14 53.9 0.0 1.8 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 OAJ21216.1 - 3.7e-14 53.0 0.0 5.5e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ21216.1 - 0.13 11.6 0.0 12 5.1 0.0 3.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PAP2 PF01569.21 OAJ21217.1 - 1.1e-16 60.8 4.7 1.1e-16 60.8 4.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily Statherin PF03875.13 OAJ21217.1 - 0.0096 16.0 4.1 0.0096 16.0 4.1 2.8 2 0 0 2 2 2 1 Statherin Romo1 PF10247.9 OAJ21217.1 - 0.056 13.8 0.2 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RecT PF03837.14 OAJ21217.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 RecT family dsrm PF00035.26 OAJ21218.1 - 3.7e-07 30.8 0.0 6.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 OAJ21218.1 - 2.8e-06 27.5 0.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAJ21218.1 - 0.00071 20.2 0.0 0.0016 19.0 0.0 1.6 2 0 0 2 2 2 1 Ribonuclease III domain PBP_N PF17093.5 OAJ21218.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus WD40 PF00400.32 OAJ21219.1 - 4.3e-42 141.3 10.1 3.1e-10 40.5 0.5 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21219.1 - 4.4e-13 49.3 1.1 5.8e-05 23.3 0.1 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ21219.1 - 0.00011 21.1 2.6 1.2 7.7 0.0 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 OAJ21219.1 - 0.00086 18.3 0.0 0.0027 16.7 0.0 1.8 1 1 1 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 OAJ21219.1 - 0.22 10.5 0.0 0.51 9.3 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region SNF2_N PF00176.23 OAJ21220.1 - 7.8e-64 215.6 0.2 1.3e-63 214.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ21220.1 - 4.4e-19 68.9 0.0 2.3e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21220.1 - 2.8e-10 40.5 0.0 7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAJ21220.1 - 0.00029 21.1 8.3 0.00029 21.1 8.3 2.2 2 0 0 2 2 2 1 HSA HDA2-3 PF11496.8 OAJ21220.1 - 0.062 12.4 0.2 6.1 5.9 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DIOX_N PF14226.6 OAJ21221.1 - 3.9e-18 66.3 0.0 6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAJ21221.1 - 2.6e-15 56.7 0.0 4.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily C2 PF00168.30 OAJ21222.1 - 5.9e-25 87.5 0.0 4.9e-16 58.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain HSP70 PF00012.20 OAJ21223.1 - 1.3e-157 525.6 0.1 1.9e-157 525.1 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ21223.1 - 9e-10 37.9 0.1 2e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAJ21223.1 - 0.04 13.6 0.4 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1769 PF08588.10 OAJ21224.1 - 1.4e-15 57.2 0.3 2.6e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Bmt2 PF11968.8 OAJ21225.1 - 2.2e-42 145.4 0.0 3.6e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 CENP-B_dimeris PF09026.10 OAJ21225.1 - 4 7.9 5.7 8.1 6.9 0.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Hexapep PF00132.24 OAJ21226.1 - 8.3e-07 28.5 1.8 0.0059 16.3 1.0 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 OAJ21226.1 - 0.039 12.9 0.1 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 L-fucokinase NTP_transferase PF00483.23 OAJ21226.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase DUF4954 PF16314.5 OAJ21226.1 - 0.25 9.4 0.0 0.36 8.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Methyltransf_25 PF13649.6 OAJ21227.1 - 3.7e-11 43.6 0.0 7.7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21227.1 - 1.2e-10 41.4 0.1 2e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ21227.1 - 1.7e-10 40.8 0.1 2.7e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAJ21227.1 - 9.5e-09 35.3 0.0 3.2e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ21227.1 - 6.9e-08 33.0 0.0 1.6e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ21227.1 - 1.3e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ21227.1 - 2.9e-05 23.2 0.0 4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 OAJ21227.1 - 5.3e-05 23.9 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ21227.1 - 0.00015 21.4 0.3 0.00028 20.5 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 OAJ21227.1 - 0.0013 18.9 0.2 0.0028 17.8 0.2 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 OAJ21227.1 - 0.0021 18.0 0.1 0.0035 17.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ21227.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OAJ21227.1 - 0.0057 16.4 0.1 0.0085 15.9 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAJ21227.1 - 0.022 14.1 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 OAJ21227.1 - 0.026 14.0 0.3 0.079 12.4 0.3 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 OAJ21227.1 - 0.056 13.0 0.1 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAJ21227.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ21227.1 - 0.1 13.6 0.0 0.36 11.9 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Ferric_reduct PF01794.19 OAJ21228.1 - 5.9e-17 62.0 9.2 5.9e-17 62.0 9.2 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ21228.1 - 4.8e-10 39.8 0.0 7.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ21228.1 - 2.1e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 OAJ21229.1 - 4.4e-19 68.8 7.7 4.4e-19 68.8 7.7 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ21229.1 - 3.5e-08 33.7 0.0 5.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ21229.1 - 3.3e-07 30.4 0.0 6.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain zf-RING_2 PF13639.6 OAJ21231.1 - 2.5e-05 24.5 6.0 4.8e-05 23.6 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ21231.1 - 0.00016 21.4 3.6 0.00038 20.2 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ21231.1 - 0.0052 16.6 5.2 0.0094 15.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ21231.1 - 0.58 10.0 5.6 1.2 8.9 5.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 OAJ21231.1 - 4.4 7.2 6.6 23 5.0 6.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ21231.1 - 5.2 7.1 6.0 12 6.0 6.0 1.6 1 1 0 1 1 1 0 zinc-RING finger domain ZZ PF00569.17 OAJ21249.1 - 4.3e-09 36.1 62.5 2.1e-05 24.2 1.9 6.5 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 OAJ21249.1 - 8.8e-05 22.4 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 OAJ21252.1 - 1.3e-43 146.1 22.6 3.1e-06 27.8 0.1 9.7 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 OAJ21252.1 - 2.3e-11 43.4 0.1 5e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ21252.1 - 1.5e-09 37.4 0.2 3.4e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAJ21252.1 - 2.4e-07 29.8 11.6 0.086 11.5 0.1 6.6 3 2 3 7 7 7 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAJ21252.1 - 0.00092 19.1 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 F-box RNA_lig_T4_1 PF09511.10 OAJ21253.1 - 2.2e-82 276.2 0.0 4.3e-82 275.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 OAJ21253.1 - 1.5e-27 96.7 0.0 3e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 OAJ21253.1 - 7.4e-24 84.7 0.0 1.4e-14 54.5 0.0 2.6 2 1 0 2 2 2 2 tRNA ligase kinase domain 2_5_RNA_ligase2 PF13563.6 OAJ21253.1 - 0.057 13.3 0.1 1.1 9.2 0.1 2.6 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily KTI12 PF08433.10 OAJ21253.1 - 0.13 11.7 0.3 2.1 7.7 0.3 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Neisseria_TspB PF05616.13 OAJ21253.1 - 1.3 7.4 4.4 1.9 6.9 4.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trp_DMAT PF11991.8 OAJ21254.1 - 3e-66 224.3 0.0 6.9e-66 223.1 0.0 1.5 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Acetyltransf_17 PF17668.1 OAJ21254.1 - 0.00043 21.1 0.2 0.0019 19.0 0.1 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF4632 PF15451.6 OAJ21254.1 - 0.11 12.6 0.1 0.38 10.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase PF00069.25 OAJ21255.1 - 1.1e-69 234.7 0.0 1.8e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21255.1 - 7e-49 166.4 0.0 1.2e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ21255.1 - 7e-05 22.3 0.0 0.00046 19.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ21255.1 - 0.0045 15.8 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RTTN_N PF14726.6 OAJ21255.1 - 0.012 16.3 1.1 0.067 14.0 0.2 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning SpoOE-like PF09388.10 OAJ21255.1 - 0.033 14.1 0.4 0.24 11.4 0.2 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein 2-oxoacid_dh PF00198.23 OAJ21256.1 - 5.7e-78 261.6 0.1 7.6e-78 261.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ21256.1 - 5.6e-22 77.4 1.7 1.3e-21 76.2 1.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ21256.1 - 4.5e-16 58.9 0.1 1.4e-15 57.3 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ21256.1 - 0.0021 17.9 1.2 0.13 12.1 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like DNA_alkylation PF08713.11 OAJ21256.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme YqfD PF06898.11 OAJ21256.1 - 0.3 9.9 1.1 0.53 9.1 1.1 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD RNA_pol_Rpc4 PF05132.14 OAJ21256.1 - 0.31 11.4 5.3 0.075 13.5 1.1 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 SspB PF04386.13 OAJ21256.1 - 0.49 10.3 4.9 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Stringent starvation protein B MTHFR PF02219.17 OAJ21257.1 - 1.4e-110 369.2 0.0 1.8e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Nuf2 PF03800.14 OAJ21258.1 - 2.7e-33 115.0 0.1 9.7e-33 113.2 0.0 2.0 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 OAJ21258.1 - 2.4e-19 69.5 16.9 2.4e-19 69.5 16.9 3.8 2 2 2 4 4 4 1 Designed helical repeat protein 10 domain Imm3 PF14425.6 OAJ21258.1 - 0.82 9.7 7.6 0.75 9.9 0.3 3.4 2 1 1 3 3 3 0 Immunity protein Imm3 HU-CCDC81_bac_2 PF18175.1 OAJ21259.1 - 0.2 11.6 0.0 0.7 9.8 0.0 2.0 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 WD40 PF00400.32 OAJ21260.1 - 1.2e-11 44.9 8.9 7.1e-05 23.5 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21260.1 - 7.4e-05 23.0 0.0 0.0066 16.7 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SIR2 PF02146.17 OAJ21261.1 - 7.1e-55 185.7 0.0 5.6e-54 182.7 0.0 2.1 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.13 OAJ21261.1 - 3.7e-07 30.1 0.3 7.5e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 OAJ21261.1 - 0.19 11.4 0.2 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L26 PF16906.5 OAJ21263.1 - 2.8e-37 127.1 3.9 3.4e-37 126.8 3.9 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAJ21263.1 - 1.4e-08 34.4 1.9 3.2e-08 33.3 1.9 1.6 1 0 0 1 1 1 1 KOW motif eRF1_1 PF03463.15 OAJ21263.1 - 0.12 12.4 1.2 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 eRF1 domain 1 Arf PF00025.21 OAJ21264.1 - 1.3e-65 220.1 0.0 1.5e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ21264.1 - 3.9e-10 39.4 0.0 1.4e-06 27.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ21264.1 - 1.2e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OAJ21264.1 - 2.1e-08 33.9 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ21264.1 - 7.2e-08 32.7 0.0 1.8e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ21264.1 - 6.7e-07 29.4 0.0 9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ21264.1 - 1.7e-05 24.3 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ21264.1 - 0.029 13.9 0.0 0.64 9.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OAJ21264.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 OAJ21264.1 - 0.092 12.3 0.0 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HMGL-like PF00682.19 OAJ21265.1 - 1.4e-72 244.4 0.0 1.9e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OAJ21265.1 - 8.5e-18 64.5 0.1 5.7e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Ribosomal_S7 PF00177.21 OAJ21265.1 - 0.051 13.2 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e Myco_19_kDa PF05481.12 OAJ21265.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Sterol_MT_C PF08498.10 OAJ21267.1 - 6.8e-28 96.8 0.8 1.1e-27 96.1 0.8 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 OAJ21267.1 - 4.3e-18 65.7 0.0 8e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21267.1 - 3.5e-17 62.6 0.0 5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ21267.1 - 8.1e-17 61.7 0.0 2e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ21267.1 - 7.5e-15 55.2 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ21267.1 - 5.1e-13 48.9 0.0 7.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 OAJ21267.1 - 3.1e-12 47.1 0.1 1.2e-11 45.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 OAJ21267.1 - 3.2e-05 23.8 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 OAJ21267.1 - 5.9e-05 22.7 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 OAJ21267.1 - 0.00012 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 OAJ21267.1 - 0.00033 21.6 0.0 0.001 20.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 OAJ21267.1 - 0.00079 18.7 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.13 OAJ21267.1 - 0.001 18.5 0.0 0.0035 16.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.17 OAJ21267.1 - 0.002 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_2 PF00891.18 OAJ21267.1 - 0.0038 16.5 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 OAJ21267.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.18 OAJ21267.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 OAJ21267.1 - 0.0063 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAJ21267.1 - 0.0084 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAJ21267.1 - 0.017 15.1 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HRM PF02793.22 OAJ21267.1 - 0.021 15.1 0.4 0.049 13.9 0.4 1.6 1 0 0 1 1 1 0 Hormone receptor domain HAMP_N3 PF18575.1 OAJ21267.1 - 0.17 11.5 0.2 0.34 10.5 0.2 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 Totivirus_coat PF05518.11 OAJ21268.1 - 7.9 4.4 10.4 10 4.0 10.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein GST_N PF02798.20 OAJ21269.1 - 5.8e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ21269.1 - 1.2e-11 44.8 0.0 2.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ21269.1 - 2.9e-11 43.4 0.0 5.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ21269.1 - 6.7e-10 39.1 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ21269.1 - 1.6e-08 34.6 0.1 2.6e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ21269.1 - 1.9e-07 31.0 0.0 3.6e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.8 OAJ21269.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3120) His_biosynth PF00977.21 OAJ21270.1 - 5.2e-33 114.4 0.0 6.6e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein START PF01852.19 OAJ21270.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 START domain Mito_carr PF00153.27 OAJ21271.1 - 3.4e-65 216.0 1.6 1.2e-21 76.4 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1318 PF07027.12 OAJ21271.1 - 0.2 12.1 0.2 0.4 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) zf-C2HC5 PF06221.13 OAJ21272.1 - 2.5e-08 33.8 8.2 4.1e-08 33.1 8.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Mito_fiss_reg PF05308.11 OAJ21272.1 - 5.2 7.1 12.5 0.65 10.0 4.0 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator MFS_1 PF07690.16 OAJ21273.1 - 3e-30 105.4 9.0 3e-30 105.4 9.0 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ21273.1 - 4.8e-11 42.2 0.1 4.8e-11 42.2 0.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter Serglycin PF04360.12 OAJ21273.1 - 0.98 9.4 6.6 2.6 8.0 6.6 1.7 1 0 0 1 1 1 0 Serglycin MutL_C PF08676.11 OAJ21274.1 - 1.9e-22 79.6 0.4 1.3e-21 76.9 0.2 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAJ21274.1 - 6.3e-16 58.1 0.0 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ21274.1 - 1.6e-11 44.2 0.0 6e-11 42.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ21274.1 - 6e-08 33.2 0.1 2.1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C97 PF05903.14 OAJ21275.1 - 1.5e-38 132.0 0.0 2.9e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain SRR1 PF07985.12 OAJ21275.1 - 7.8e-11 41.9 0.2 1.5e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 SRR1 TAP_C PF03943.13 OAJ21275.1 - 0.14 11.8 0.1 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 TAP C-terminal domain MGC-24 PF05283.11 OAJ21276.1 - 1.1 9.7 4.4 1.4 9.3 4.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Peptidase_M1_N PF17900.1 OAJ21277.1 - 3.2e-11 43.8 0.0 5.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 OAJ21277.1 - 0.045 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain LRR_4 PF12799.7 OAJ21278.1 - 0.00035 20.9 4.4 3.7 8.1 0.0 5.2 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ21278.1 - 0.0028 18.0 2.9 21 6.2 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 OAJ21278.1 - 0.004 17.1 4.3 1.6 9.0 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.6 OAJ21278.1 - 0.029 14.2 0.6 11 5.9 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 OAJ21278.1 - 0.061 13.2 1.8 0.23 11.4 1.8 2.0 1 1 0 1 1 1 0 F-box-like CSRNP_N PF16019.5 OAJ21278.1 - 0.37 10.7 1.5 6.7 6.6 0.5 2.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Astro_capsid_p PF12226.8 OAJ21278.1 - 3.6 6.6 8.8 1.4 8.0 0.3 2.2 2 0 0 2 2 2 0 Turkey astrovirus capsid protein Polysacc_deac_1 PF01522.21 OAJ21279.1 - 8.1e-25 87.1 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAJ21279.1 - 3.7e-05 23.1 0.0 0.00016 21.0 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAJ21279.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF930 PF06059.12 OAJ21279.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) XRN_M PF17846.1 OAJ21300.1 - 2.9 6.7 5.0 5 6.0 5.0 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Aldedh PF00171.22 OAJ21302.1 - 3.2e-105 352.3 0.0 3.8e-105 352.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ERCC4 PF02732.15 OAJ21304.1 - 1.4e-15 57.8 0.0 1.9e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.16 OAJ21304.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 OAJ21304.1 - 0.057 13.2 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HhH-GPD PF00730.25 OAJ21306.1 - 5.4e-17 62.2 0.0 9.7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ21306.1 - 3.5e-08 32.9 0.0 1.7e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAJ21306.1 - 0.042 14.5 0.1 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain Roughex PF06020.11 OAJ21306.1 - 0.18 10.9 3.9 0.36 9.9 3.9 1.5 1 0 0 1 1 1 0 Drosophila roughex protein EndIII_4Fe-2S PF10576.9 OAJ21306.1 - 0.25 11.7 1.6 0.56 10.6 1.6 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III cwf18 PF08315.12 OAJ21306.1 - 0.66 10.6 4.9 0.26 11.9 1.2 2.2 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor TAFII55_N PF04658.13 OAJ21307.1 - 6.6e-51 172.2 0.3 5.3e-50 169.3 0.0 2.5 2 0 0 2 2 2 1 TAFII55 protein conserved region Atg14 PF10186.9 OAJ21307.1 - 1.9 7.5 11.3 3 6.8 11.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NIF PF03031.18 OAJ21308.1 - 2.7e-23 82.4 0.0 4.9e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OAJ21308.1 - 0.027 14.2 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Barttin PF15462.6 OAJ21308.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) BRCA-2_OB1 PF09103.10 OAJ21309.1 - 2.8e-33 114.5 0.0 5.4e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 OAJ21309.1 - 2.3e-08 33.9 0.5 3.9e-08 33.2 0.5 1.3 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 OAJ21309.1 - 0.00011 21.8 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 BRCA2 repeat 2-Hacid_dh_C PF02826.19 OAJ21310.1 - 5.2e-53 179.0 0.0 9.9e-53 178.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ21310.1 - 1.6e-35 121.7 0.0 2.2e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAJ21310.1 - 0.00046 20.4 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase YopX PF09643.10 OAJ21310.1 - 0.089 12.9 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 YopX protein AdoHcyase_NAD PF00670.21 OAJ21310.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mito_carr PF00153.27 OAJ21311.1 - 7.5e-53 176.4 4.4 6.3e-21 74.1 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TMEM126 PF07114.11 OAJ21311.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 126 DUF2955 PF11168.8 OAJ21311.1 - 0.13 12.1 0.6 0.33 10.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) Apolipoprotein PF01442.18 OAJ21313.1 - 0.0076 16.1 4.7 0.013 15.4 4.7 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 OAJ21313.1 - 0.039 14.0 2.5 0.057 13.4 0.5 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF883 PF05957.13 OAJ21313.1 - 0.3 11.7 6.4 5.5 7.7 1.9 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Voltage_CLC PF00654.20 OAJ21314.1 - 4.4e-89 299.2 31.3 7.9e-89 298.4 31.3 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OAJ21314.1 - 0.16 12.4 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 CBS domain Acyltransferase PF01553.21 OAJ21315.1 - 4.3e-35 120.3 0.0 6.5e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Lactamase_B_6 PF16661.5 OAJ21316.1 - 1.3e-42 145.4 0.0 6.9e-24 84.4 0.0 3.3 3 0 0 3 3 3 3 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAJ21316.1 - 8.9e-34 117.1 0.0 8.9e-34 117.1 0.0 2.9 5 0 0 5 5 5 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAJ21316.1 - 7.4e-14 52.0 0.0 2.6e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 OAJ21316.1 - 0.16 11.9 0.0 0.49 10.4 0.0 1.8 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Lyase_1 PF00206.20 OAJ21317.1 - 1.9e-116 388.9 0.0 3.2e-116 388.1 0.0 1.4 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAJ21317.1 - 1.3e-19 70.4 0.0 3.8e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Lipase_3 PF01764.25 OAJ21318.1 - 1.5e-06 28.2 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 OAJ21318.1 - 0.082 12.5 0.1 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Forkhead PF00250.18 OAJ21321.1 - 1.5e-23 82.9 0.0 2.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Peptidase_S8 PF00082.22 OAJ21323.1 - 2.4e-36 125.6 0.0 4.7e-36 124.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family RPT PF13446.6 OAJ21324.1 - 0.01 15.7 0.0 78 3.3 0.0 4.7 5 0 0 5 5 5 0 A repeated domain in UCH-protein DPBB_1 PF03330.18 OAJ21325.1 - 0.0091 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase DUF4148 PF13663.6 OAJ21325.1 - 0.16 12.2 0.8 0.24 11.6 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Cas_Cas2CT1978 PF09707.10 OAJ21326.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) tRNA-synt_2d PF01409.20 OAJ21327.1 - 1.7e-86 289.7 0.0 2.3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAJ21327.1 - 4.7e-14 52.4 1.4 8.5e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 OAJ21327.1 - 5.5e-08 32.5 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OAJ21327.1 - 6.1e-05 22.2 0.4 0.0019 17.3 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAJ21327.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 OAJ21327.1 - 0.047 13.7 0.6 0.14 12.2 0.6 1.9 1 1 0 1 1 1 0 PheRS DNA binding domain 2 Glyco_hydro_43 PF04616.14 OAJ21328.1 - 1e-35 123.5 0.4 1.2e-35 123.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AP2 PF00847.20 OAJ21328.1 - 0.12 12.6 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 AP2 domain TSP9 PF11493.8 OAJ21328.1 - 1.2 9.9 3.4 19 6.0 1.6 2.4 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Ferritin_2 PF13668.6 OAJ21329.1 - 8.9e-43 145.7 4.1 1.3e-42 145.2 4.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Methyltransf_28 PF02636.17 OAJ21330.1 - 3.2e-36 125.3 0.0 8.1e-36 124.0 0.0 1.6 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.10 OAJ21330.1 - 3e-28 98.9 8.8 1.2e-09 37.9 0.0 6.1 5 1 0 5 5 5 3 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 OAJ21330.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ferritin_2 PF13668.6 OAJ21332.1 - 1.5e-42 145.1 4.1 2.2e-42 144.5 4.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain UPF0029 PF01205.19 OAJ21333.1 - 7.3e-20 71.3 0.0 2.5e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 PaaX PF07848.12 OAJ21333.1 - 0.087 13.1 0.6 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 PaaX-like protein CTP_transf_like PF01467.26 OAJ21334.1 - 1.1e-08 35.4 0.0 1.2e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 OAJ21334.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase DUF4449 PF14613.6 OAJ21335.1 - 1.7e-33 116.0 0.1 1.7e-33 116.0 0.1 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF4449) AAA_15 PF13175.6 OAJ21335.1 - 6.1 6.4 10.9 4.4 6.9 8.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain Con-6 PF10346.9 OAJ21336.1 - 1.5e-08 34.5 0.1 2.9e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 GPI-anchored PF10342.9 OAJ21337.1 - 5.3e-09 36.7 1.1 5.3e-09 36.7 1.1 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Apt1 PF10351.9 OAJ21337.1 - 0.53 9.1 3.6 0.69 8.7 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.11 OAJ21337.1 - 0.59 8.3 22.2 1 7.5 22.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SOG2 PF10428.9 OAJ21337.1 - 2.4 7.3 12.7 2.7 7.1 12.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Rib_recp_KP_reg PF05104.12 OAJ21337.1 - 4.3 8.3 8.6 6.7 7.7 8.6 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Sporozoite_P67 PF05642.11 OAJ21337.1 - 6.3 4.8 14.4 7.3 4.5 14.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PEX11 PF05648.14 OAJ21338.1 - 1.2e-62 211.3 2.5 1.3e-62 211.2 2.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4864 PF16156.5 OAJ21338.1 - 0.061 14.0 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) Polysacc_deac_1 PF01522.21 OAJ21357.1 - 4.6e-17 62.1 0.0 9.3e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Anemone_cytotox PF06369.12 OAJ21357.1 - 0.075 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Sea anemone cytotoxic protein UPF0180 PF03698.13 OAJ21357.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Glyco_hydro_57 PF03065.15 OAJ21357.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Cation_ATPase_C PF00689.21 OAJ21358.1 - 8.8e-44 149.4 2.7 8.8e-44 149.4 2.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ21358.1 - 9.9e-38 129.5 0.1 9.9e-38 129.5 0.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ21358.1 - 3.9e-21 74.9 0.1 8.4e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ21358.1 - 6.6e-17 62.5 5.1 2.7e-16 60.5 5.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ21358.1 - 1.2e-09 37.7 0.1 5.7e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ21358.1 - 0.00014 21.7 0.3 0.023 14.4 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP1_TM PF14812.6 OAJ21358.1 - 0.093 13.1 1.7 3.1 8.2 2.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hydrolase_4 PF12146.8 OAJ21359.1 - 8.4e-07 28.5 0.2 3.8e-06 26.3 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 OAJ21359.1 - 0.00014 21.0 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 OAJ21359.1 - 0.0081 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 OAJ21359.1 - 0.0086 15.7 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.11 OAJ21359.1 - 0.073 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Glycos_transf_1 PF00534.20 OAJ21360.1 - 7.1e-28 97.3 0.0 3.2e-27 95.1 0.0 2.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ21360.1 - 2.7e-24 86.1 0.0 7.5e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ21360.1 - 8.2e-24 84.5 0.0 1.5e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ21360.1 - 4.8e-14 53.1 0.0 1.5e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAJ21360.1 - 0.0055 17.1 0.7 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_17 PF04724.13 OAJ21361.1 - 4.1e-116 387.8 0.0 5.5e-116 387.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 F-box-like PF12937.7 OAJ21363.1 - 1.3e-11 44.2 1.5 1.7e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ21363.1 - 5.3e-06 26.2 1.6 9.3e-06 25.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain PPTA PF01239.22 OAJ21363.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat PQQ_2 PF13360.6 OAJ21363.1 - 0.095 12.3 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain NOC3p PF07540.11 OAJ21364.1 - 1.4e-26 92.8 1.3 7.6e-21 74.4 0.0 3.0 3 0 0 3 3 3 2 Nucleolar complex-associated protein CBF PF03914.17 OAJ21364.1 - 1.8e-12 47.6 0.0 1.8e-12 47.6 0.0 3.4 2 1 0 2 2 2 1 CBF/Mak21 family GREB1 PF15782.5 OAJ21364.1 - 8.4 3.4 9.2 13 2.8 9.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer IF4E PF01652.18 OAJ21365.1 - 2.4e-46 157.4 0.0 4.3e-46 156.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E ATP_synt_H PF05493.13 OAJ21366.1 - 5.6e-21 74.8 5.2 6.4e-21 74.6 5.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Pilin_N PF07790.11 OAJ21366.1 - 0.1 13.5 0.4 0.14 13.1 0.4 1.2 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal DUF4131 PF13567.6 OAJ21366.1 - 0.73 9.5 2.7 0.78 9.4 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OppC_N PF12911.7 OAJ21366.1 - 5.9 6.9 8.6 6.2 6.9 3.0 2.2 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C RL10P_insert PF17777.1 OAJ21367.1 - 5.9e-22 77.4 0.1 1.1e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAJ21367.1 - 5.6e-15 55.3 0.0 9e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 sCache_3_2 PF17203.4 OAJ21367.1 - 0.14 12.3 0.1 0.66 10.1 0.0 1.9 2 0 0 2 2 2 0 Single cache domain 3 NOA36 PF06524.12 OAJ21367.1 - 0.25 10.7 10.1 0.34 10.2 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ21367.1 - 0.27 9.3 12.2 0.41 8.7 12.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 OAJ21367.1 - 0.32 10.1 4.6 0.46 9.6 4.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CENP-B_dimeris PF09026.10 OAJ21367.1 - 0.86 10.0 14.9 1.7 9.1 14.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ21367.1 - 0.87 10.0 10.7 2 8.9 10.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L1 PF00687.21 OAJ21368.1 - 8e-46 156.3 1.1 9.2e-46 156.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 OAJ21368.1 - 1.4 9.0 5.9 0.6 10.2 1.7 2.0 1 1 0 2 2 2 0 Protein of unknown function MBOAT PF03062.19 OAJ21369.1 - 4.5e-48 164.4 0.6 3e-47 161.7 0.6 2.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_T PF00929.24 OAJ21370.1 - 1.4e-08 35.5 0.0 1.7e-06 28.7 0.0 2.8 3 0 0 3 3 3 2 Exonuclease JAB PF01398.21 OAJ21371.1 - 6.7e-06 26.1 0.0 5.7e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF883 PF05957.13 OAJ21371.1 - 0.16 12.6 4.9 0.79 10.4 0.6 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Complex1_LYR_2 PF13233.6 OAJ21372.1 - 9.8e-08 32.6 0.2 1.2e-07 32.3 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ21372.1 - 1.2e-05 25.2 0.6 2.3e-05 24.4 0.6 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) UPF0020 PF01170.18 OAJ21373.1 - 9.7e-16 58.0 0.0 1e-14 54.7 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 OAJ21373.1 - 0.00083 18.9 0.0 0.1 12.0 0.0 2.4 1 1 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 OAJ21373.1 - 0.0013 19.3 0.0 0.0041 17.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ21373.1 - 0.029 15.1 0.0 0.092 13.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21373.1 - 0.12 12.2 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 OAJ21373.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain N2227 PF07942.12 OAJ21373.1 - 0.14 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein N6_Mtase PF02384.16 OAJ21373.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase TP_methylase PF00590.20 OAJ21375.1 - 2.8e-36 125.5 0.2 6.7e-36 124.2 0.2 1.7 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 OAJ21375.1 - 3.1e-11 42.5 0.4 6.8e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 OAJ21375.1 - 2.2e-09 37.7 0.0 1.3e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ21375.1 - 7.5e-08 31.9 0.0 4.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal VIR_N PF15912.5 OAJ21375.1 - 0.092 12.3 10.9 2.2 7.8 5.3 2.4 2 0 0 2 2 2 0 Virilizer, N-terminal Adaptin_binding PF10199.9 OAJ21376.1 - 0.0071 16.9 3.7 0.0071 16.9 3.7 3.2 2 2 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DprA_WH PF17782.1 OAJ21376.1 - 0.18 11.9 4.8 0.16 12.1 1.0 2.8 2 1 1 3 3 3 0 DprA winged helix domain PikAIV_N PF18605.1 OAJ21376.1 - 8.6 6.0 8.1 0.21 11.2 0.5 2.2 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain NUMOD3 PF07460.11 OAJ21377.1 - 0.066 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) RNA_pol_L_2 PF13656.6 OAJ21378.1 - 7.8e-28 96.1 0.0 1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ21378.1 - 9.5e-08 31.4 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.6 OAJ21378.1 - 0.0076 14.3 0.0 0.0085 14.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase ox_reductase_C PF08635.10 OAJ21379.1 - 2.3e-77 257.5 0.1 3.6e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OAJ21379.1 - 2.5e-18 67.0 0.0 6.9e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ21379.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DASH_Spc34 PF08657.10 OAJ21380.1 - 0.0024 17.7 0.5 0.061 13.1 0.5 2.3 1 1 0 1 1 1 1 DASH complex subunit Spc34 PhyH PF05721.13 OAJ21380.1 - 0.1 12.8 0.3 0.26 11.5 0.1 1.7 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) APS_kinase PF01583.20 OAJ21381.1 - 1.3e-69 233.1 0.0 1.6e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAJ21381.1 - 1.2e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ21381.1 - 0.00052 20.6 0.0 0.00069 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ21381.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 OAJ21381.1 - 0.0045 16.7 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ21381.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 OAJ21381.1 - 0.042 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Zeta_toxin PF06414.12 OAJ21381.1 - 0.072 12.4 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 OAJ21381.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family PRK PF00485.18 OAJ21381.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family 6PF2K PF01591.18 OAJ21381.1 - 0.24 10.7 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Polysacc_deac_1 PF01522.21 OAJ21382.1 - 6.3e-23 81.0 0.0 1.1e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 OAJ21382.1 - 0.00042 19.9 3.7 0.095 12.2 0.0 2.3 2 0 0 2 2 2 2 Virulence protein nec1 Polysacc_deac_1 PF01522.21 OAJ21383.1 - 7.8e-25 87.2 0.0 1.8e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 OAJ21383.1 - 0.14 10.2 11.2 0.17 9.9 11.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CTU2 PF10288.9 OAJ21384.1 - 2.6e-18 66.3 0.3 2.6e-18 66.3 0.3 2.1 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Lar_restr_allev PF14354.6 OAJ21384.1 - 0.42 11.0 1.7 0.45 10.9 0.1 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar MIP PF00230.20 OAJ21385.1 - 5.1e-39 134.3 12.1 6.8e-39 133.9 12.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PTPS_related PF10131.9 OAJ21385.1 - 0.015 13.7 0.2 0.015 13.7 0.2 1.5 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Calici_coat_C PF08435.11 OAJ21385.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DASH_Dam1 PF08653.10 OAJ21386.1 - 1.6e-19 69.4 0.3 2.6e-19 68.8 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Histidinol_dh PF00815.20 OAJ21386.1 - 0.08 11.9 0.6 0.39 9.7 0.1 1.9 2 0 0 2 2 2 0 Histidinol dehydrogenase Sen15 PF09631.10 OAJ21387.1 - 1.2e-11 44.8 0.0 4.2e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein CBFD_NFYB_HMF PF00808.23 OAJ21388.1 - 1.8e-15 56.9 0.0 3.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 OAJ21388.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Nup88 PF10168.9 OAJ21388.1 - 0.034 12.0 0.9 0.17 9.6 0.7 1.8 2 0 0 2 2 2 0 Nuclear pore component zf-CCCH PF00642.24 OAJ21389.1 - 3.9e-13 48.9 15.3 1.4e-06 28.1 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ21389.1 - 0.00067 19.6 9.3 0.0018 18.3 1.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ21389.1 - 0.0022 18.2 3.5 0.0069 16.6 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 OAJ21389.1 - 0.19 12.4 0.3 0.19 12.4 0.3 2.4 2 1 0 2 2 2 0 Torus domain Proteasome PF00227.26 OAJ21390.1 - 5.9e-59 198.7 0.1 7.7e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ21390.1 - 1.3e-14 53.5 0.3 3.1e-14 52.3 0.3 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DsrH PF04077.12 OAJ21390.1 - 0.14 12.3 0.3 0.3 11.2 0.1 1.6 2 0 0 2 2 2 0 DsrH like protein Nitrate_red_gam PF02665.14 OAJ21390.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Shadoo PF14999.6 OAJ21391.1 - 0.28 11.3 10.6 0.078 13.1 1.0 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective F-box-like PF12937.7 OAJ21392.1 - 6e-13 48.5 1.8 1.5e-12 47.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ21392.1 - 9.5e-08 31.7 0.2 5.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 F-box domain PQQ PF01011.21 OAJ21392.1 - 3.4e-05 23.6 0.1 0.35 10.9 0.0 2.8 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 OAJ21392.1 - 0.0017 18.0 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain NAD_binding_10 PF13460.6 OAJ21393.1 - 0.0017 18.3 0.7 0.015 15.2 0.1 2.6 2 1 0 2 2 2 1 NAD(P)H-binding Mito_carr PF00153.27 OAJ21394.1 - 2.3e-10 40.2 0.3 2e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Spc24 PF08286.11 OAJ21396.1 - 1.5e-08 34.8 0.1 1.2e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 ATG16 PF08614.11 OAJ21396.1 - 0.015 15.6 5.9 0.015 15.6 5.9 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 OAJ21396.1 - 0.023 15.0 10.7 1.2 9.4 3.7 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain CENP-H PF05837.12 OAJ21396.1 - 0.038 14.4 4.3 0.07 13.5 4.3 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Peptidase_S46 PF10459.9 OAJ21396.1 - 0.061 12.0 1.2 0.075 11.7 1.2 1.1 1 0 0 1 1 1 0 Peptidase S46 EzrA PF06160.12 OAJ21396.1 - 0.073 11.2 2.2 0.091 10.9 2.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FapA PF03961.13 OAJ21396.1 - 0.13 10.9 0.6 0.17 10.4 0.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A KELK PF15796.5 OAJ21396.1 - 0.27 11.7 9.4 1.7 9.1 4.0 2.5 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase zf-C4pol PF14260.6 OAJ21396.1 - 0.35 11.3 2.1 6.5 7.3 0.1 2.3 1 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta TMF_DNA_bd PF12329.8 OAJ21396.1 - 0.47 10.5 6.9 0.69 9.9 2.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 OAJ21396.1 - 0.5 10.5 11.2 2.4 8.3 11.2 2.0 1 1 0 1 1 1 0 Tropomyosin like Snapin_Pallidin PF14712.6 OAJ21396.1 - 0.52 10.8 2.7 3.6 8.1 0.2 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Med9 PF07544.13 OAJ21396.1 - 0.72 10.0 7.6 13 5.9 0.4 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ACCA PF03255.14 OAJ21396.1 - 1.4 8.8 5.5 1.7 8.5 0.3 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit XhlA PF10779.9 OAJ21396.1 - 5.8 7.2 5.7 28 5.0 0.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA ThuA PF06283.11 OAJ21398.1 - 1.7e-55 188.5 0.6 5e-45 154.3 0.2 2.1 2 0 0 2 2 2 2 Trehalose utilisation DUF4983 PF16356.5 OAJ21398.1 - 0.13 13.1 0.2 1.1 10.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4983) Serglycin PF04360.12 OAJ21398.1 - 4.2 7.3 7.2 8.1 6.4 7.2 1.4 1 0 0 1 1 1 0 Serglycin Methyltransf_16 PF10294.9 OAJ21399.1 - 2.4e-14 53.4 0.0 8.2e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase DEAD PF00270.29 OAJ21400.1 - 7.1e-26 91.0 0.0 1.6e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAJ21400.1 - 7.9e-20 71.4 1.3 2.5e-19 69.8 1.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAJ21400.1 - 1.6e-13 51.0 0.2 3e-12 46.9 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21400.1 - 1.8e-06 28.1 0.0 4.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 OAJ21400.1 - 6.6e-06 26.5 0.0 1.5e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 DNA replication factor CDT1 like Peptidase_M19 PF01244.21 OAJ21419.1 - 5.8e-97 324.7 0.0 6.7e-97 324.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 OAJ21419.1 - 0.018 14.9 0.0 0.032 14.0 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase Myb_DNA-binding PF00249.31 OAJ21420.1 - 6.9e-16 58.2 4.7 2e-09 37.5 1.2 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ21420.1 - 8.1e-12 45.2 1.5 1.4e-06 28.4 0.1 3.7 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ21420.1 - 0.063 13.7 0.3 0.063 13.7 0.3 3.4 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain SET PF00856.28 OAJ21421.1 - 4.4e-18 66.2 0.0 2e-17 64.1 0.0 2.1 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAJ21421.1 - 1.5e-12 48.1 7.0 1.5e-12 48.1 7.0 2.2 2 0 0 2 2 2 1 Pre-SET motif PsaN PF05479.11 OAJ21421.1 - 0.14 12.3 3.1 0.17 12.1 0.3 2.1 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) YL1 PF05764.13 OAJ21422.1 - 2e-41 142.7 24.9 3.5e-41 142.0 24.9 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 OAJ21422.1 - 5.7e-10 38.8 0.0 9.5e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1682 PF07946.14 OAJ21423.1 - 1.1e-62 212.1 0.0 1.3e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Xan_ur_permease PF00860.20 OAJ21423.1 - 0.058 12.1 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Permease family TIMELESS PF04821.14 OAJ21423.1 - 0.76 9.0 3.9 1.1 8.5 3.9 1.1 1 0 0 1 1 1 0 Timeless protein Nucleoporin_C PF03177.14 OAJ21424.1 - 8.1e-78 262.6 6.9 1.2e-77 262.1 6.9 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAJ21424.1 - 2.4e-16 59.5 0.0 3.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like UvrD_C PF13361.6 OAJ21424.1 - 0.14 11.6 0.8 0.29 10.5 0.2 1.9 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DIE2_ALG10 PF04922.12 OAJ21425.1 - 2.5e-121 405.7 7.7 7.6e-94 315.2 7.3 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family ADH_zinc_N PF00107.26 OAJ21426.1 - 2.3e-17 63.2 0.7 4.2e-17 62.3 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ21426.1 - 7.5e-09 36.7 0.0 1.6e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ21426.1 - 0.027 14.4 0.0 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ21426.1 - 0.096 12.6 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase DUF3835 PF12927.7 OAJ21427.1 - 3.8e-06 27.7 9.6 0.00016 22.5 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) Histone_HNS PF00816.21 OAJ21427.1 - 0.41 11.5 3.5 0.58 11.0 0.6 2.7 2 0 0 2 2 2 0 H-NS histone family ACR_tran PF00873.19 OAJ21428.1 - 0.07 10.8 2.6 0.075 10.7 2.6 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family CAMSAP_CC1 PF17095.5 OAJ21428.1 - 0.088 12.7 2.4 0.27 11.1 1.5 2.3 1 1 1 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF2130 PF09903.9 OAJ21428.1 - 0.092 12.0 1.1 0.13 11.5 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) MF_alpha_N PF05436.11 OAJ21428.1 - 0.14 12.0 1.8 1.2 9.0 1.8 2.1 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus ALMT PF11744.8 OAJ21428.1 - 1 8.1 6.7 1.2 7.8 6.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 OAJ21428.1 - 5.5 6.9 20.6 7.1 6.5 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RasGAP PF00616.19 OAJ21430.1 - 4e-59 199.8 0.0 7.7e-59 198.9 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ21430.1 - 4.2e-39 133.8 0.1 4.2e-39 133.8 0.1 2.0 3 0 0 3 3 3 1 RasGAP C-terminus YabA PF06156.13 OAJ21430.1 - 0.13 12.9 0.5 45 4.8 0.2 3.1 2 0 0 2 2 2 0 Initiation control protein YabA PCRF PF03462.18 OAJ21432.1 - 9.1e-49 166.0 0.0 9.1e-49 166.0 0.0 2.1 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAJ21432.1 - 9.4e-37 125.5 2.1 9.4e-37 125.5 2.1 1.8 2 0 0 2 2 2 1 RF-1 domain DEAD PF00270.29 OAJ21433.1 - 8.2e-30 103.9 0.0 6e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ21433.1 - 1.1e-21 77.2 0.0 3.1e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21433.1 - 0.029 14.4 0.0 0.12 12.3 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Cmc1 PF08583.10 OAJ21434.1 - 3e-16 59.2 1.1 4.2e-16 58.7 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 OAJ21434.1 - 0.56 10.4 3.5 2 8.6 3.5 1.9 1 1 0 1 1 1 0 CHCH domain Tfb4 PF03850.14 OAJ21435.1 - 1.3e-53 182.3 4.9 2.2e-28 99.5 0.0 3.8 1 1 1 2 2 2 2 Transcription factor Tfb4 XRCC4 PF06632.12 OAJ21435.1 - 0.046 12.6 0.2 0.073 11.9 0.2 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Myb_DNA-bind_7 PF15963.5 OAJ21436.1 - 7e-26 89.9 0.1 7e-26 89.9 0.1 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OAJ21436.1 - 1.2e-08 35.0 0.1 3.2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ21436.1 - 0.026 14.8 0.2 0.056 13.7 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aa_trans PF01490.18 OAJ21437.1 - 1e-72 245.1 21.3 1.4e-72 244.7 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ21437.1 - 0.0002 20.5 19.0 0.00056 19.1 19.0 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family ParD_antitoxin PF03693.14 OAJ21438.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Acyl-CoA_dh_2 PF08028.11 OAJ21438.1 - 0.019 15.2 1.1 6 7.1 0.1 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Yippee-Mis18 PF03226.14 OAJ21439.1 - 3e-14 53.1 0.1 3.9e-14 52.7 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PI31_Prot_N PF11566.8 OAJ21440.1 - 2.4e-50 170.5 0.0 3.2e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAJ21440.1 - 2.6e-14 54.2 16.4 2.6e-14 54.2 16.4 3.2 3 0 0 3 3 3 1 PI31 proteasome regulator F-box-like PF12937.7 OAJ21441.1 - 0.00018 21.3 0.2 0.00075 19.4 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ21441.1 - 0.053 13.4 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAJ21441.1 - 0.054 13.4 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 F-box RRM_1 PF00076.22 OAJ21442.1 - 3.9e-19 68.3 0.0 6.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 OAJ21444.1 - 4.2e-30 104.9 31.9 5.2e-30 104.5 30.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Halogen_Hydrol PF10112.9 OAJ21444.1 - 3.7 7.5 0.0 3.7 7.5 0.0 3.6 4 1 1 5 5 5 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ferric_reduct PF01794.19 OAJ21446.1 - 6.4e-17 61.8 10.1 6.4e-17 61.8 10.1 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ21446.1 - 2.3e-13 50.6 0.0 3.4e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ21446.1 - 1.8e-05 24.8 0.1 0.0061 16.6 0.1 3.1 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ21446.1 - 0.02 15.5 0.0 1.9 9.2 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAJ21446.1 - 0.037 14.6 8.6 2.4 8.8 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DJ-1_PfpI PF01965.24 OAJ21447.1 - 2.8e-13 50.0 0.0 5.9e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAJ21447.1 - 4.5e-07 29.8 0.0 4.1e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like Toprim_Crpt PF13342.6 OAJ21447.1 - 0.07 13.1 0.3 0.33 11.0 0.0 2.2 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase GATase_3 PF07685.14 OAJ21447.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Ank_4 PF13637.6 OAJ21448.1 - 2.3e-15 56.7 1.4 2.7e-12 47.0 0.3 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ21448.1 - 2.6e-15 56.8 1.0 9.8e-12 45.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ21448.1 - 2.3e-10 39.8 0.1 7.2e-05 22.9 0.1 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ21448.1 - 1.8e-09 37.6 0.4 9.5e-06 25.8 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 OAJ21448.1 - 1.6e-08 34.6 2.1 0.00029 21.0 0.3 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Nramp PF01566.18 OAJ21449.1 - 5.7e-87 292.0 25.9 3.1e-48 164.6 10.9 2.8 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein LRR_8 PF13855.6 OAJ21450.1 - 1.7e-13 50.1 15.4 5.1e-09 35.8 6.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ21450.1 - 4.3e-13 49.2 8.9 1.9e-05 24.9 2.7 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ21450.1 - 0.44 10.7 13.5 9.4 6.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OAJ21450.1 - 1.9 9.3 13.5 24 6.0 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat EHN PF06441.12 OAJ21451.1 - 2.9e-20 72.6 0.5 6.8e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ21451.1 - 1.6e-13 50.9 0.1 3.1e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 OAJ21453.1 - 1.1e-20 73.9 33.2 4.4e-17 62.0 12.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ21453.1 - 7.1e-07 28.4 0.0 0.036 12.9 2.1 3.4 2 1 1 3 3 3 3 MFS_1 like family MFS_3 PF05977.13 OAJ21453.1 - 0.11 10.9 5.6 0.2 10.0 0.0 2.6 3 0 0 3 3 3 0 Transmembrane secretion effector ATG22 PF11700.8 OAJ21453.1 - 1.4 7.5 15.3 0.029 13.0 3.1 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like DUF3270 PF11674.8 OAJ21453.1 - 2.9 8.1 0.0 2.9 8.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3270) Mg_trans_NIPA PF05653.14 OAJ21454.1 - 6.1e-25 87.9 9.9 1e-13 51.1 3.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA PUNUT PF16913.5 OAJ21454.1 - 0.35 10.0 7.2 1.2 8.3 2.3 2.4 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Neurensin PF14927.6 OAJ21454.1 - 0.37 10.5 3.1 16 5.2 0.4 2.6 2 0 0 2 2 2 0 Neurensin EamA PF00892.20 OAJ21454.1 - 0.44 10.7 25.0 0.069 13.3 7.4 2.9 2 0 0 2 2 2 0 EamA-like transporter family DUF872 PF05915.12 OAJ21454.1 - 0.55 10.4 1.9 11 6.2 0.2 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Pkinase PF00069.25 OAJ21455.1 - 8.2e-48 163.1 0.0 2e-46 158.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21455.1 - 1.8e-17 63.5 0.0 5.4e-16 58.6 0.0 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ21455.1 - 0.00036 19.4 0.0 0.00075 18.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ21455.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ21455.1 - 0.0045 16.9 0.6 0.016 15.1 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ21455.1 - 0.0066 15.8 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kelch_4 PF13418.6 OAJ21456.1 - 6.9e-34 115.6 12.5 2.5e-05 24.2 0.4 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ21456.1 - 8.6e-30 102.1 5.6 1.3e-05 24.7 0.1 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OAJ21456.1 - 4.1e-27 93.7 9.1 5.8e-06 26.2 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAJ21456.1 - 1.1e-24 86.2 11.4 5.9e-07 29.6 0.2 7.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ21456.1 - 3.4e-23 80.7 8.9 6.7e-05 22.7 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 OAJ21456.1 - 3.4e-22 77.9 7.5 8.7e-05 22.7 0.1 6.2 5 1 1 6 6 6 5 Kelch motif Mitoc_mL59 PF18126.1 OAJ21457.1 - 6.9e-28 97.5 9.3 1.9e-27 96.1 9.3 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 WD40 PF00400.32 OAJ21458.1 - 2.2e-06 28.3 12.0 0.016 16.1 0.2 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21458.1 - 2.1e-05 24.7 0.0 0.0032 17.7 0.0 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rpr2 PF04032.16 OAJ21459.1 - 0.037 14.3 0.2 0.1 12.9 0.1 1.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain BRD4_CDT PF17105.5 OAJ21459.1 - 0.38 10.4 2.1 0.83 9.3 2.1 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Neisseria_TspB PF05616.13 OAJ21459.1 - 4.8 5.6 15.1 7.5 4.9 15.1 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF5602 PF18197.1 OAJ21459.1 - 5 7.7 0.0 5 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5602) Adaptin_N PF01602.20 OAJ21460.1 - 1.1e-53 182.7 0.0 4.8e-31 107.9 0.0 3.1 3 0 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 OAJ21460.1 - 1.8e-08 34.6 0.0 1.1e-05 25.5 0.0 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ21460.1 - 4.2e-05 23.5 3.0 0.93 9.9 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 OAJ21460.1 - 0.00048 20.5 3.3 0.00048 20.5 3.3 6.3 5 1 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 OAJ21460.1 - 0.016 15.7 1.0 0.016 15.7 1.0 7.0 7 1 1 8 8 8 0 HEAT-like repeat DUF2052 PF09747.9 OAJ21460.1 - 0.026 14.7 0.2 0.026 14.7 0.2 4.2 4 0 0 4 4 4 0 Coiled-coil domain containing protein (DUF2052) CTNNBL PF08216.11 OAJ21461.1 - 9.9e-34 115.6 0.1 3.6e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 OAJ21461.1 - 0.031 14.3 1.6 1.6 8.9 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OAJ21461.1 - 0.06 13.7 2.4 0.85 10.1 0.1 3.7 3 0 0 3 3 3 0 HEAT repeats Arm_3 PF16186.5 OAJ21461.1 - 0.068 12.7 0.0 0.29 10.7 0.0 2.1 1 0 0 1 1 1 0 Atypical Arm repeat Pox_E10 PF04805.12 OAJ21461.1 - 0.074 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region HEAT PF02985.22 OAJ21461.1 - 0.19 12.0 0.6 13 6.4 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat AT_hook PF02178.19 OAJ21462.1 - 0.0023 17.6 19.5 0.12 12.3 4.4 2.8 2 0 0 2 2 2 2 AT hook motif DUF448 PF04296.13 OAJ21462.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF448) RFX5_DNA_bdg PF14621.6 OAJ21462.1 - 1.6 8.4 17.1 0.036 13.8 4.6 2.9 1 1 2 3 3 3 0 RFX5 DNA-binding domain Helicase_C_2 PF13307.6 OAJ21483.1 - 5e-53 179.8 0.0 1.3e-52 178.4 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAJ21483.1 - 5.3e-44 149.9 0.0 1.7e-43 148.3 0.0 1.8 1 1 0 1 1 1 1 DEAD_2 PhoH PF02562.16 OAJ21483.1 - 0.0035 16.8 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 OAJ21483.1 - 0.0057 16.7 0.1 4.4 7.3 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ21483.1 - 0.011 16.0 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 OAJ21483.1 - 0.013 15.3 0.0 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mis14 PF08641.12 OAJ21483.1 - 1 9.7 6.5 0.2 12.0 1.4 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like SNF2_N PF00176.23 OAJ21484.1 - 1.4e-58 198.3 0.0 1.4e-57 195.0 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ21484.1 - 2e-15 57.1 0.0 8.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ21484.1 - 2.4e-08 34.0 0.0 4.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ21484.1 - 1.2e-07 31.9 0.0 3.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 OAJ21484.1 - 5e-07 29.5 3.4 5e-07 29.5 3.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ21484.1 - 6.7e-06 25.9 3.9 6.7e-06 25.9 3.9 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ21484.1 - 1.6e-05 24.9 4.9 1.6e-05 24.9 4.9 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 OAJ21484.1 - 2.4e-05 24.3 1.2 2.4e-05 24.3 1.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ21484.1 - 3.4e-05 23.6 5.6 3.4e-05 23.6 5.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ21484.1 - 7.1e-05 22.6 4.8 7.1e-05 22.6 4.8 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ21484.1 - 0.00014 22.1 5.7 0.00014 22.1 5.7 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAJ21484.1 - 0.00067 19.6 5.5 0.00067 19.6 5.5 2.4 2 1 0 2 2 1 1 zinc-RING finger domain HTH_3 PF01381.22 OAJ21484.1 - 0.0094 16.0 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix CRISPR_Cse2 PF09485.10 OAJ21484.1 - 0.068 13.7 2.9 0.31 11.6 2.9 2.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) zf-RING_6 PF14835.6 OAJ21484.1 - 0.071 13.0 3.3 0.15 12.0 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 OAJ21484.1 - 0.2 11.5 1.3 0.49 10.2 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RVT_1 PF00078.27 OAJ21486.1 - 6e-09 35.7 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TB2_DP1_HVA22 PF03134.19 OAJ21487.1 - 4.4e-29 100.2 5.3 4.4e-29 100.2 5.3 1.4 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bindin PF02084.15 OAJ21489.1 - 5.3 7.2 9.0 0.89 9.8 3.3 2.0 1 1 1 2 2 2 0 Bindin FMN_red PF03358.15 OAJ21492.1 - 2.1e-08 34.1 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 OAJ21492.1 - 0.08 13.1 0.1 0.18 12.0 0.1 1.7 1 1 0 1 1 1 0 Flavodoxin RRM_1 PF00076.22 OAJ21493.1 - 1.6e-24 85.5 0.0 9.5e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 OAJ21493.1 - 2e-18 64.9 0.0 0.00021 20.8 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat TFIIA PF03153.13 OAJ21493.1 - 0.00085 19.4 25.5 0.00085 19.4 25.5 6.1 5 1 0 5 5 4 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ21493.1 - 0.001 18.7 30.5 0.001 18.7 30.5 6.6 6 1 0 6 6 5 2 Spt20 family RRM_occluded PF16842.5 OAJ21493.1 - 0.0017 18.1 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 OAJ21493.1 - 0.04 13.4 0.0 0.04 13.4 0.0 3.4 4 0 0 4 4 3 0 RNA-recognition motif MecA PF05389.12 OAJ21493.1 - 0.065 12.9 4.0 0.18 11.4 4.0 1.7 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) XRN_M PF17846.1 OAJ21493.1 - 0.094 11.7 0.8 0.19 10.7 0.8 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Tim54 PF11711.8 OAJ21493.1 - 0.73 8.6 9.5 2.2 7.0 9.5 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rxt3 PF08642.10 OAJ21493.1 - 1 10.1 3.6 5.1 7.9 3.6 2.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 SpoIIP PF07454.11 OAJ21493.1 - 1.6 8.2 10.3 4.3 6.7 10.3 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PRC2_HTH_1 PF18118.1 OAJ21493.1 - 3.2 8.6 8.3 19 6.1 8.3 2.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DUF4770 PF15994.5 OAJ21493.1 - 3.3 7.9 12.8 26 5.0 12.8 2.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Het-C PF07217.11 OAJ21493.1 - 6.2 5.2 5.8 10 4.5 5.8 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C tRNA-synt_1g PF09334.11 OAJ21494.1 - 4.6e-80 269.3 0.8 1.7e-74 250.9 0.5 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ21494.1 - 2.5e-14 52.4 0.2 3.9e-07 28.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAJ21494.1 - 1.1e-07 31.5 0.1 0.0039 16.6 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MT0933_antitox PF14013.6 OAJ21494.1 - 0.06 13.7 1.3 5 7.5 0.0 2.5 2 0 0 2 2 2 0 MT0933-like antitoxin protein HLH PF00010.26 OAJ21495.1 - 1.7e-06 27.9 0.0 4.7e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain FYDLN_acid PF09538.10 OAJ21495.1 - 0.13 12.9 18.1 0.85 10.3 2.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.11 OAJ21495.1 - 0.15 12.1 10.6 2 8.5 1.4 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal SDA1 PF05285.12 OAJ21495.1 - 0.22 10.9 21.9 0.8 9.1 7.1 2.2 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.13 OAJ21495.1 - 0.32 10.9 12.3 0.51 10.2 2.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 OAJ21495.1 - 0.4 8.8 21.3 1.1 7.4 7.3 2.1 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 OAJ21495.1 - 0.88 8.8 29.7 0.51 9.6 9.6 2.3 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ21495.1 - 0.97 7.5 24.0 0.74 7.9 7.6 2.1 2 0 0 2 2 2 0 DNA polymerase phi YL1 PF05764.13 OAJ21495.1 - 1.2 9.1 24.9 3 7.9 6.6 2.5 2 0 0 2 2 2 0 YL1 nuclear protein BCDHK_Adom3 PF10436.9 OAJ21496.1 - 0.02 14.7 1.5 0.031 14.1 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase FH2 PF02181.23 OAJ21496.1 - 0.2 10.7 11.9 0.27 10.3 11.9 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain CDPS PF16715.5 OAJ21496.1 - 2.9 7.5 9.9 0.65 9.6 5.0 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase DUF1129 PF06570.11 OAJ21496.1 - 4.4 6.7 6.4 3.3 7.2 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) SOG2 PF10428.9 OAJ21496.1 - 5.8 6.0 17.2 8.1 5.5 17.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LMBR1 PF04791.16 OAJ21496.1 - 9 5.1 6.6 11 4.8 6.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Uricase PF01014.18 OAJ21497.1 - 1.1e-60 203.7 0.0 6.5e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Uricase Arrestin_C PF02752.22 OAJ21498.1 - 1.3e-10 41.8 0.0 4.3e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain PAM2 PF07145.15 OAJ21498.1 - 0.021 14.5 0.4 0.06 13.0 0.4 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Arrestin_N PF00339.29 OAJ21498.1 - 0.11 12.5 0.1 30 4.6 0.0 3.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_L22 PF00237.19 OAJ21499.1 - 1.9e-36 124.4 0.1 2.5e-36 124.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L23eN PF03939.13 OAJ21500.1 - 4.6e-23 81.2 10.9 8.6e-23 80.3 10.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAJ21500.1 - 8.4e-11 42.1 0.2 8.4e-11 42.1 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 OAJ21500.1 - 0.0033 17.7 0.7 0.0047 17.2 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) Cyt-b5 PF00173.28 OAJ21501.1 - 1.5e-09 37.9 0.0 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DHBP_synthase PF00926.19 OAJ21502.1 - 6.9e-76 254.1 0.0 8.4e-76 253.8 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Septin PF00735.18 OAJ21507.1 - 4.1e-43 147.7 0.0 2.9e-15 56.3 0.0 4.7 4 0 0 4 4 4 4 Septin Nop25 PF09805.9 OAJ21507.1 - 0.0092 16.5 31.1 0.0092 16.5 31.1 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) MMR_HSR1 PF01926.23 OAJ21507.1 - 0.11 12.6 0.0 0.78 9.8 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Spem1 PF15670.5 OAJ21507.1 - 7.3 6.1 6.5 1.9 8.0 2.4 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 zf-RING_2 PF13639.6 OAJ21508.1 - 1.8e-12 47.4 7.1 2.8e-12 46.8 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAJ21508.1 - 2.7e-09 37.2 3.2 5.4e-09 36.2 3.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAJ21508.1 - 2.8e-09 36.5 2.4 5.1e-09 35.7 2.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 OAJ21508.1 - 6.3e-08 32.4 4.0 9.9e-08 31.7 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ21508.1 - 1.9e-07 30.8 4.4 3.1e-07 30.1 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ21508.1 - 5.5e-07 29.4 2.5 8.4e-07 28.9 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ21508.1 - 8.3e-06 25.8 1.0 1.5e-05 24.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 OAJ21508.1 - 6e-05 22.8 3.2 0.0001 22.1 3.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAJ21508.1 - 9.5e-05 22.2 3.1 0.00015 21.5 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAJ21508.1 - 0.017 14.9 4.9 0.03 14.1 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAJ21508.1 - 0.018 15.1 3.8 0.035 14.1 3.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 OAJ21508.1 - 0.16 11.8 4.9 0.28 11.1 4.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 OAJ21508.1 - 0.2 12.0 4.2 0.35 11.2 4.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 OAJ21508.1 - 0.27 11.3 0.8 0.48 10.5 0.8 1.3 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 OAJ21508.1 - 0.31 10.7 3.7 0.58 9.8 3.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 OAJ21508.1 - 0.98 9.7 3.4 2 8.7 3.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 OAJ21508.1 - 0.99 9.6 8.0 1.7 8.8 8.0 1.4 1 0 0 1 1 1 0 RING-variant domain Peptidase_C48 PF02902.19 OAJ21509.1 - 3.3e-12 46.7 0.0 6.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OAJ21509.1 - 6e-12 45.8 0.3 2.5e-07 31.0 0.2 2.8 1 1 1 2 2 2 2 MULE transposase domain Glyoxal_oxid_N PF07250.11 OAJ21509.1 - 0.071 12.3 0.2 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus SWIM PF04434.17 OAJ21509.1 - 0.38 10.5 2.9 0.23 11.2 0.6 1.8 2 0 0 2 2 2 0 SWIM zinc finger MCM PF00493.23 OAJ21510.1 - 1.3e-99 331.9 0.0 1.8e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ21510.1 - 8.1e-38 129.1 0.0 1.4e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAJ21510.1 - 1.5e-32 113.0 33.8 2e-32 112.6 30.9 2.7 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAJ21510.1 - 6.7e-26 90.5 0.3 2.5e-25 88.7 0.3 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ21510.1 - 7.1e-13 49.0 0.0 1.9e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ21510.1 - 1.5e-08 34.3 0.0 6.9e-07 28.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ21510.1 - 6.7e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ21510.1 - 0.00045 20.1 0.0 0.0068 16.3 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_gyraseB_C PF00986.21 OAJ21510.1 - 0.02 15.1 0.3 2.5 8.3 0.0 2.7 3 0 0 3 3 2 0 DNA gyrase B subunit, carboxyl terminus Zn_ribbon_2 PF12674.7 OAJ21510.1 - 0.05 14.3 0.2 0.12 13.0 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA_lid_2 PF17863.1 OAJ21510.1 - 0.057 13.3 2.7 0.078 12.8 0.1 2.6 2 0 0 2 2 2 0 AAA lid domain Sigma54_activat PF00158.26 OAJ21510.1 - 0.059 13.1 0.0 0.38 10.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Osteopontin PF00865.18 OAJ21511.1 - 0.2 11.1 13.2 0.36 10.3 13.2 1.3 1 0 0 1 1 1 0 Osteopontin PPP4R2 PF09184.11 OAJ21511.1 - 0.59 9.7 4.9 1 8.9 4.9 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAJ21511.1 - 3.5 6.9 14.0 6 6.1 14.0 1.3 1 0 0 1 1 1 0 NOA36 protein zf-MYND PF01753.18 OAJ21513.1 - 0.00044 20.3 1.4 0.0015 18.6 1.4 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 OAJ21513.1 - 0.0076 17.4 4.9 0.0076 17.4 4.9 7.3 1 1 3 6 6 6 1 ECL1/2/3 zinc binding proteins DUF2116 PF09889.9 OAJ21513.1 - 0.34 10.9 1.5 0.74 9.8 1.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pkinase PF00069.25 OAJ21514.1 - 3.7e-42 144.5 0.0 3.1e-40 138.2 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21514.1 - 1.2e-22 80.4 0.0 3.1e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ21514.1 - 0.0008 18.8 0.3 0.0018 17.7 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MdcG PF10620.9 OAJ21515.1 - 0.052 13.3 0.4 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG SUIM_assoc PF16619.5 OAJ21516.1 - 2.6 8.2 16.4 0.48 10.5 5.0 4.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FMO-like PF00743.19 OAJ21540.1 - 8.7e-32 110.2 0.0 2.4e-18 65.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ21540.1 - 3.4e-09 36.4 0.4 7.8e-06 25.4 0.0 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ21540.1 - 1.9e-07 30.6 0.0 4.5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ21540.1 - 2.8e-07 30.7 0.0 1.6e-05 25.0 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ21540.1 - 8.2e-05 21.9 0.1 0.0079 15.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAJ21540.1 - 0.00014 21.3 0.0 0.025 13.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ21540.1 - 0.00041 20.5 0.0 0.00094 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ21540.1 - 0.0047 16.6 0.1 0.091 12.3 0.0 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase Malic_M PF03949.15 OAJ21540.1 - 0.042 13.1 0.0 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Thi4 PF01946.17 OAJ21540.1 - 0.11 11.7 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.16 OAJ21541.1 - 6.4e-14 51.6 11.0 6.4e-14 51.6 11.0 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ21541.1 - 0.00075 18.5 1.9 0.0035 16.3 0.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Asparaginase PF00710.20 OAJ21542.1 - 2.6e-34 118.5 0.0 3.8e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAJ21542.1 - 7.5e-14 51.9 0.0 3.2e-13 49.9 0.0 2.1 2 2 1 3 3 3 1 Glutaminase/Asparaginase C-terminal domain FMO-like PF00743.19 OAJ21543.1 - 4.5e-32 111.2 0.0 4.9e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ21543.1 - 7.9e-12 45.0 0.0 3.3e-07 29.9 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ21543.1 - 2e-09 37.1 0.0 4.8e-08 32.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ21543.1 - 7.3e-08 31.9 0.1 9e-06 25.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ21543.1 - 1.3e-06 28.5 0.3 0.065 13.2 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ21543.1 - 0.0002 21.5 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ21543.1 - 0.00078 19.1 0.1 0.014 15.0 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ21543.1 - 0.022 14.0 0.0 0.16 11.2 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAJ21543.1 - 0.066 13.8 0.1 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.15 OAJ21543.1 - 0.12 11.7 0.0 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Eno-Rase_NADH_b PF12242.8 OAJ21543.1 - 0.19 11.5 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_2 PF00890.24 OAJ21543.1 - 1.4 7.9 3.1 4.1 6.4 3.1 1.8 1 1 1 2 2 2 0 FAD binding domain DUF2188 PF09954.9 OAJ21544.1 - 1.7 8.9 3.8 1.4 9.1 1.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) LOR PF04525.12 OAJ21545.1 - 4e-18 65.7 0.0 4.9e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related OPT PF03169.15 OAJ21546.1 - 3.6e-174 580.8 54.4 4.2e-174 580.6 54.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AMP-binding PF00501.28 OAJ21549.1 - 6.8e-249 825.5 0.0 6.6e-85 285.2 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 OAJ21549.1 - 4.1e-167 556.5 0.0 1.6e-43 149.1 0.0 6.1 5 1 0 5 5 5 5 Condensation domain PP-binding PF00550.25 OAJ21549.1 - 2.8e-31 107.7 3.2 4.3e-10 39.8 0.1 4.2 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ21549.1 - 3.6e-24 85.6 0.0 5.8e-06 27.2 0.0 3.9 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain DUF1776 PF08643.10 OAJ21549.1 - 0.031 13.7 0.1 5.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Fungal family of unknown function (DUF1776) DUF3037 PF11236.8 OAJ21549.1 - 0.083 13.3 5.9 0.59 10.6 0.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Asparaginase PF00710.20 OAJ21549.1 - 0.26 10.8 2.2 18 4.8 0.0 2.9 3 0 0 3 3 3 0 Asparaginase, N-terminal Methyltransf_11 PF08241.12 OAJ21550.1 - 1.7e-10 41.4 0.0 8e-10 39.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ21550.1 - 3.2e-10 40.6 0.0 1.2e-08 35.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ21550.1 - 6.1e-06 26.9 0.0 0.00019 22.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ21550.1 - 0.0019 18.1 0.0 0.0086 15.9 0.0 1.8 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21550.1 - 0.1 12.4 0.0 1.1 9.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 OAJ21551.1 - 0.0091 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ21551.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAJ21551.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ21552.1 - 2.3e-07 30.9 0.0 5.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ21552.1 - 0.0084 15.7 2.0 0.023 14.3 1.6 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FMO-like PF00743.19 OAJ21552.1 - 0.0084 14.6 0.3 0.043 12.2 0.3 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ21552.1 - 0.048 12.9 0.6 6.1 6.0 0.6 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ21552.1 - 0.085 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 OAJ21552.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 OAJ21552.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 OAJ21552.1 - 0.2 10.9 0.2 1.4 8.1 0.2 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SLAC1 PF03595.17 OAJ21554.1 - 3.1e-63 214.0 46.2 4.9e-63 213.4 46.2 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel AIRC PF00731.20 OAJ21554.1 - 0.15 11.6 1.5 0.38 10.3 1.5 1.6 1 0 0 1 1 1 0 AIR carboxylase GMC_oxred_N PF00732.19 OAJ21555.1 - 5.2e-52 177.1 0.0 8.8e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ21555.1 - 1.2e-35 123.2 0.6 2.4e-35 122.1 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ21555.1 - 0.00065 18.9 1.0 0.12 11.5 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 OAJ21555.1 - 0.00086 18.5 0.2 0.00086 18.5 0.2 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAJ21555.1 - 0.00096 18.5 0.1 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ21555.1 - 0.002 18.3 0.6 0.007 16.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ21555.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 OAJ21555.1 - 0.031 13.9 1.1 0.24 10.9 0.9 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 OAJ21555.1 - 0.15 12.3 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain G6PD_C PF02781.16 OAJ21556.1 - 5.3e-107 357.3 0.0 7e-107 356.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAJ21556.1 - 1.5e-59 201.6 0.1 2.9e-59 200.6 0.1 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Allantoicase PF03561.15 OAJ21557.1 - 2.7e-84 280.4 0.0 1.9e-41 141.4 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 OAJ21557.1 - 7e-53 179.2 0.0 1e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase Ecl1 PF12855.7 OAJ21558.1 - 6.2e-05 24.2 0.4 6.2e-05 24.2 0.4 12.6 5 4 6 12 12 12 1 ECL1/2/3 zinc binding proteins adh_short PF00106.25 OAJ21559.1 - 6.8e-16 58.3 0.2 8.5e-06 25.4 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ21559.1 - 1.9e-08 34.1 0.3 0.0002 21.0 0.0 2.6 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ21559.1 - 3.9e-06 26.9 0.3 2.2e-05 24.5 0.1 2.2 2 1 0 2 2 2 1 KR domain CRAL_TRIO PF00650.20 OAJ21560.1 - 6.6e-35 120.2 0.0 1.2e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ21560.1 - 6.9e-09 35.8 0.3 1.5e-08 34.7 0.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.20 OAJ21560.1 - 2.1e-07 31.5 0.1 1.8e-06 28.4 0.2 2.5 2 0 0 2 2 2 1 ThiS family Aa_trans PF01490.18 OAJ21561.1 - 5.7e-45 153.7 31.7 6.9e-45 153.5 31.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MutL_C PF08676.11 OAJ21562.1 - 4.6e-06 26.5 0.0 2.6e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 MutL C terminal dimerisation domain Ribosomal_L32e PF01655.18 OAJ21562.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L32 WBP-1 PF11669.8 OAJ21563.1 - 0.2 12.3 0.0 0.2 12.3 0.0 2.1 3 0 0 3 3 3 0 WW domain-binding protein 1 HemY_N PF07219.13 OAJ21563.1 - 0.51 10.6 6.8 8.5 6.6 2.7 3.5 3 0 0 3 3 3 0 HemY protein N-terminus SLATT_5 PF18160.1 OAJ21563.1 - 1.3 8.3 3.2 28 4.0 0.8 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TMEM208_SND2 PF05620.11 OAJ21563.1 - 1.7 8.4 4.2 0.68 9.7 0.1 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF4381 PF14316.6 OAJ21563.1 - 8.1 6.7 10.9 5.4 7.3 1.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2985 PF11204.8 OAJ21564.1 - 1e-25 89.7 1.5 1.8e-25 88.9 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.6 OAJ21564.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative sensor UCMA PF17085.5 OAJ21564.1 - 0.096 12.7 1.3 0.44 10.5 1.3 2.1 1 0 0 1 1 1 0 Unique cartilage matrix associated protein TEX19 PF15553.6 OAJ21564.1 - 0.12 12.3 0.4 0.53 10.2 0.2 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 Glyco_hydro_16 PF00722.21 OAJ21565.1 - 1.4e-34 119.1 1.4 2.8e-34 118.1 1.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 OAJ21565.1 - 0.054 14.0 16.9 0.12 12.9 16.9 1.5 1 0 0 1 1 1 0 Chitin recognition protein Somatomedin_B PF01033.17 OAJ21565.1 - 1.8 9.0 9.9 2.9 8.3 2.6 2.3 2 0 0 2 2 2 0 Somatomedin B domain Meth_synt_2 PF01717.18 OAJ21566.1 - 2.6e-148 493.6 0.1 5.9e-142 472.7 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAJ21566.1 - 8.8e-117 390.1 0.0 6.4e-110 367.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.9 OAJ21566.1 - 0.015 15.0 0.2 0.039 13.7 0.2 1.8 1 0 0 1 1 1 0 Short C-terminal domain UQ_con PF00179.26 OAJ21567.1 - 2.7e-41 140.5 0.0 3.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAJ21567.1 - 9.5e-22 76.6 0.1 1.4e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 OAJ21567.1 - 0.00016 21.6 0.0 0.00026 20.8 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain DUF1421 PF07223.11 OAJ21567.1 - 0.005 16.7 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain (DUF1421) UBA PF00627.31 OAJ21567.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Prok-E2_B PF14461.6 OAJ21567.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DNA_ligase_OB_2 PF14743.6 OAJ21568.1 - 5.6e-27 93.6 0.3 1.1e-26 92.6 0.3 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 OAJ21568.1 - 1.5e-10 41.0 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 OAJ21568.1 - 0.00015 22.1 0.0 0.00074 19.9 0.0 2.0 1 1 0 1 1 1 1 RNA ligase SWIM PF04434.17 OAJ21568.1 - 0.095 12.4 0.6 0.22 11.3 0.6 1.6 1 0 0 1 1 1 0 SWIM zinc finger Transp_cyt_pur PF02133.15 OAJ21570.1 - 1.2e-127 426.4 43.1 3.4e-121 405.1 33.5 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin FHA PF00498.26 OAJ21571.1 - 1.8e-14 53.8 0.0 3.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ21571.1 - 0.0048 17.2 0.0 0.16 12.3 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ABC_tran PF00005.27 OAJ21573.1 - 9.2e-46 155.8 0.0 3.2e-28 99.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 OAJ21573.1 - 6.6e-39 134.2 26.2 2.8e-22 79.7 16.5 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ21573.1 - 4.5e-12 45.9 0.3 8e-06 25.5 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ21573.1 - 3.9e-07 29.7 0.3 0.023 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ21573.1 - 6.7e-06 26.1 0.5 2.5 7.8 0.0 4.2 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 OAJ21573.1 - 1.3e-05 24.2 1.1 0.047 12.5 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 OAJ21573.1 - 0.00025 21.3 0.7 0.069 13.4 0.2 3.5 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ21573.1 - 0.00036 20.0 0.2 0.02 14.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 OAJ21573.1 - 0.00038 20.5 0.3 1.2 9.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 OAJ21573.1 - 0.00063 20.3 0.0 1.9 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 OAJ21573.1 - 0.00064 19.8 0.7 0.087 12.9 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 OAJ21573.1 - 0.0012 19.3 2.3 0.078 13.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 OAJ21573.1 - 0.011 15.3 2.4 0.21 11.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 OAJ21573.1 - 0.021 14.7 1.6 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 OAJ21573.1 - 0.03 14.5 0.0 7.9 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAJ21573.1 - 0.047 13.4 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 OAJ21573.1 - 0.071 13.1 0.2 1.6 8.8 0.3 2.7 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ21573.1 - 0.071 13.7 0.0 0.64 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAJ21573.1 - 0.1 12.7 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 OAJ21573.1 - 0.11 11.5 0.7 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 OAJ21573.1 - 0.14 11.8 1.6 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAJ21573.1 - 0.21 11.2 3.4 24 4.4 0.0 3.5 3 1 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 OAJ21573.1 - 0.37 11.1 6.1 5.5 7.3 0.3 4.1 4 2 0 4 4 3 0 Putative exonuclease SbcCD, C subunit DUF4083 PF13314.6 OAJ21573.1 - 5.3 7.1 9.5 0.52 10.3 3.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DHHC PF01529.20 OAJ21588.1 - 9e-31 106.8 13.2 1.7e-30 105.8 13.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAJ21588.1 - 2.8e-26 91.9 0.4 1.3e-14 54.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ21588.1 - 1.2e-21 74.4 4.9 5.8e-05 23.2 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 OAJ21588.1 - 1.5e-21 76.4 6.9 5e-08 33.3 0.2 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ21588.1 - 8.2e-20 70.6 4.2 9.4e-05 22.6 0.1 5.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAJ21588.1 - 4.7e-18 64.7 15.7 4.4e-05 23.7 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat DUF2304 PF10066.9 OAJ21588.1 - 0.4 10.9 1.9 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pet127 PF08634.10 OAJ21589.1 - 5.2e-101 337.7 0.0 7.6e-101 337.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF89 PF01937.19 OAJ21591.1 - 5.5e-106 354.5 0.0 8.1e-106 353.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 NAD_binding_4 PF07993.12 OAJ21592.1 - 8.4e-24 84.1 0.0 1.6e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ21592.1 - 3.1e-16 59.6 0.0 5.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAJ21592.1 - 5.7e-15 54.8 0.0 1.2e-14 53.8 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 OAJ21592.1 - 0.0025 17.7 0.0 0.009 15.9 0.0 1.9 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 OAJ21592.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding_C PF13193.6 OAJ21592.1 - 0.15 13.0 0.0 0.52 11.3 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PNP_UDP_1 PF01048.20 OAJ21594.1 - 8.9e-26 90.6 0.0 1.2e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_16 PF10294.9 OAJ21595.1 - 1.5e-14 54.1 0.0 3.9e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ21595.1 - 0.18 12.5 0.4 46 4.8 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain SPO22 PF08631.10 OAJ21596.1 - 1.2e-08 34.8 1.5 1.2e-08 34.8 1.5 4.2 4 2 1 5 5 5 1 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 OAJ21596.1 - 8.3 7.0 10.2 3.7 8.1 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21596.1 - 10 6.9 8.4 7 7.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 OAJ21597.1 - 2.7e-53 179.8 1.6 3.2e-53 179.6 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e KH_1 PF00013.29 OAJ21598.1 - 0.005 16.6 0.2 0.011 15.5 0.2 1.6 1 0 0 1 1 1 1 KH domain RAP1 PF07218.11 OAJ21598.1 - 0.011 14.0 1.7 0.014 13.7 1.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DTHCT PF08070.11 OAJ21598.1 - 5.8 7.7 8.9 33 5.3 8.9 2.3 1 1 0 1 1 1 0 DTHCT (NUC029) region DEAD PF00270.29 OAJ21599.1 - 4.8e-43 146.9 0.0 1.4e-42 145.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ21599.1 - 4.1e-30 104.4 0.0 1.2e-27 96.5 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Tub_N PF16322.5 OAJ21599.1 - 4.2 7.7 28.7 4.1 7.8 27.3 1.6 2 0 0 2 2 2 0 Tubby N-terminal HGTP_anticodon2 PF12745.7 OAJ21599.1 - 7.5 6.0 22.0 13 5.2 22.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Pro_isomerase PF00160.21 OAJ21600.1 - 8.3e-37 126.9 0.0 2.4e-36 125.4 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 OAJ21600.1 - 0.0045 17.4 0.1 0.0045 17.4 0.1 4.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) DNA_primase_lrg PF04104.14 OAJ21601.1 - 1.7e-81 273.5 0.0 2.5e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PSP1 PF04468.12 OAJ21602.1 - 2e-30 104.9 0.3 3.4e-30 104.2 0.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Aminotran_5 PF00266.19 OAJ21603.1 - 2.2e-05 23.6 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SART-1 PF03343.13 OAJ21604.1 - 2.4e-138 462.5 64.5 3.1e-138 462.1 64.5 1.0 1 0 0 1 1 1 1 SART-1 family MFS_1 PF07690.16 OAJ21605.1 - 4.5e-42 144.2 29.1 4.5e-42 144.2 29.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ21605.1 - 2.6e-09 36.5 11.6 2.6e-09 36.5 11.6 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter Utp14 PF04615.13 OAJ21605.1 - 0.023 13.3 5.2 0.03 12.9 5.2 1.0 1 0 0 1 1 1 0 Utp14 protein GTP_EFTU PF00009.27 OAJ21606.1 - 2.7e-19 69.5 0.0 5.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ21606.1 - 3.4e-10 40.2 0.6 6.5e-09 36.1 0.5 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ21606.1 - 0.0014 18.7 0.0 0.0051 16.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 OAJ21606.1 - 0.034 13.9 0.1 10 5.9 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CBS PF00571.28 OAJ21607.1 - 3.3e-15 56.3 7.0 0.0003 21.2 0.4 5.7 6 0 0 6 6 6 4 CBS domain Actin PF00022.19 OAJ21608.1 - 8.8e-59 199.1 0.0 1.1e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Actin DUF4677 PF15726.5 OAJ21608.1 - 0.14 12.3 0.3 0.29 11.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) CCDC71L PF15374.6 OAJ21608.1 - 1.3 8.2 7.8 2.4 7.3 7.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF737 PF05300.11 OAJ21608.1 - 4 7.7 15.2 2.9 8.2 13.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF737) Cornichon PF03311.14 OAJ21609.1 - 6.3e-53 178.3 13.2 7.2e-53 178.1 13.2 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2189 PF09955.9 OAJ21609.1 - 0.64 10.3 7.7 1.9 8.7 0.2 2.4 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Rer1 PF03248.13 OAJ21611.1 - 1.5e-75 252.7 0.0 1.9e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 OAJ21611.1 - 1.3 8.6 7.8 0.056 13.1 1.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF4131 PF13567.6 OAJ21611.1 - 2 8.0 6.6 9.6 5.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Nop52 PF05997.12 OAJ21612.1 - 8.6e-64 215.3 0.0 1.2e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 ABATE PF07336.11 OAJ21612.1 - 0.015 16.0 14.5 0.053 14.2 3.5 3.5 3 0 0 3 3 3 0 Putative stress-induced transcription regulator RRN3 PF05327.11 OAJ21612.1 - 2 6.9 3.7 3.3 6.1 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ21612.1 - 2.5 6.1 6.6 3.8 5.5 6.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi SBDS_C PF09377.10 OAJ21613.1 - 3.7e-37 126.9 0.4 6.5e-37 126.1 0.4 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OAJ21613.1 - 2.1e-33 114.3 1.0 3.1e-33 113.7 0.5 1.6 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CFAP91 PF14738.6 OAJ21613.1 - 0.046 13.8 0.4 0.09 12.8 0.4 1.5 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 Csm1 PF12539.8 OAJ21615.1 - 3.3e-09 37.3 0.1 2.9e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 LPP PF04728.13 OAJ21615.1 - 0.14 12.5 6.6 7.9 7.0 2.0 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper YlqD PF11068.8 OAJ21615.1 - 0.22 11.9 13.3 2.1 8.7 5.4 2.3 2 0 0 2 2 2 0 YlqD protein HAUS-augmin3 PF14932.6 OAJ21615.1 - 0.66 9.5 23.8 0.11 12.0 9.8 2.2 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 TSC22 PF01166.18 OAJ21615.1 - 0.81 10.1 10.8 5.1 7.5 0.7 3.5 2 1 0 3 3 3 0 TSC-22/dip/bun family OmpH PF03938.14 OAJ21615.1 - 1.4 9.3 20.3 0.4 11.0 2.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 OAJ21615.1 - 2.4 7.5 24.6 0.76 9.2 16.1 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 TRAF_BIRC3_bd PF16673.5 OAJ21615.1 - 3.4 7.5 13.8 2.3 8.1 3.8 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Jnk-SapK_ap_N PF09744.9 OAJ21615.1 - 4 7.6 24.4 0.84 9.9 3.4 2.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 OAJ21615.1 - 5.2 7.1 18.0 0.94 9.5 0.9 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 OAJ21615.1 - 7.7 5.3 27.4 0.43 9.4 13.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 OAJ21615.1 - 7.8 6.7 19.8 1.7 8.8 7.8 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 TCTP PF00838.17 OAJ21616.1 - 2.9e-52 177.4 0.2 3.2e-52 177.2 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FAD_binding_2 PF00890.24 OAJ21617.1 - 5e-126 421.1 3.1 8e-126 420.5 3.1 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAJ21617.1 - 5e-44 149.4 5.3 5.4e-44 149.3 1.9 2.2 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term NAD_binding_4 PF07993.12 OAJ21617.1 - 1.6e-23 83.2 0.0 2.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 OAJ21617.1 - 1.6e-19 69.8 0.3 3.6e-18 65.4 0.3 2.7 2 1 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 OAJ21617.1 - 7.6e-13 48.5 0.0 1.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thi4 PF01946.17 OAJ21617.1 - 0.00081 18.7 0.3 0.12 11.5 0.1 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAJ21617.1 - 0.00091 18.4 1.1 0.14 11.2 2.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A 3Beta_HSD PF01073.19 OAJ21617.1 - 0.003 16.6 0.0 0.0078 15.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_3 PF01494.19 OAJ21617.1 - 0.012 14.9 0.2 0.026 13.8 0.2 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 OAJ21617.1 - 0.029 13.6 0.3 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 OAJ21617.1 - 0.041 13.8 0.0 0.21 11.5 0.0 2.2 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 OAJ21617.1 - 0.2 10.7 0.1 0.63 9.1 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Amb_V_allergen PF03913.13 OAJ21620.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Amb V Allergen HMG_box PF00505.19 OAJ21621.1 - 8.9e-18 64.5 12.2 5e-10 39.7 2.2 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ21621.1 - 2.6e-14 53.5 10.2 7.4e-08 32.9 2.4 2.9 2 0 0 2 2 2 2 HMG-box domain Imm58 PF15581.6 OAJ21621.1 - 0.039 14.1 4.3 0.28 11.3 0.0 2.7 3 0 0 3 3 3 0 Immunity protein 58 Spc7_N PF15402.6 OAJ21621.1 - 0.35 9.1 18.9 0.32 9.2 17.8 1.4 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Mucin PF01456.17 OAJ21621.1 - 1.8 8.5 28.6 0.32 11.0 24.3 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein Sulfate_transp PF00916.20 OAJ21622.1 - 1e-37 129.8 15.5 1.5e-37 129.3 15.5 1.1 1 0 0 1 1 1 1 Sulfate permease family Sulfate_transp PF00916.20 OAJ21623.1 - 5.7e-14 51.7 1.1 8.9e-14 51.0 1.1 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 OAJ21623.1 - 2.1e-11 43.7 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAJ21623.1 - 8e-11 41.6 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 OAJ21623.1 - 0.023 15.0 0.1 0.054 13.8 0.1 1.7 1 0 0 1 1 1 0 STAS domain DUF4395 PF14340.6 OAJ21623.1 - 3.8 7.9 10.8 0.96 9.8 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) vATP-synt_E PF01991.18 OAJ21625.1 - 9.1e-60 201.5 14.9 1.1e-59 201.3 14.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit P21-Arc PF04062.14 OAJ21626.1 - 1.1e-78 263.2 0.0 1.3e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pyr_redox_2 PF07992.14 OAJ21627.1 - 3.3e-40 138.1 0.0 4.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ21627.1 - 9.1e-13 48.6 0.2 2.6e-08 34.3 0.1 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 OAJ21627.1 - 1.8e-08 33.7 2.3 4.5e-05 23.0 0.5 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ21627.1 - 7.3e-08 31.4 2.5 5.5e-05 22.4 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAJ21627.1 - 3.6e-07 30.5 9.5 1.8e-05 25.1 3.1 2.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ21627.1 - 0.00032 20.1 1.5 0.00055 19.3 0.6 1.9 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 OAJ21627.1 - 0.0039 16.5 3.1 0.26 10.5 2.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Caleosin PF05042.13 OAJ21627.1 - 0.098 12.6 0.2 1 9.3 0.1 2.3 1 1 1 2 2 2 0 Caleosin related protein Hydrolase_3 PF08282.12 OAJ21627.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NAD_binding_7 PF13241.6 OAJ21627.1 - 0.11 13.0 1.7 2.4 8.6 0.0 2.7 3 0 0 3 3 2 0 Putative NAD(P)-binding EF-hand_8 PF13833.6 OAJ21627.1 - 0.14 12.0 1.6 0.93 9.4 0.4 2.3 2 0 0 2 2 2 0 EF-hand domain pair Peptidase_M15_3 PF08291.11 OAJ21627.1 - 0.19 11.8 0.0 0.51 10.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase M15 Fe_hyd_lg_C PF02906.14 OAJ21627.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Helicase_C PF00271.31 OAJ21628.1 - 0.0038 17.6 0.1 0.0079 16.5 0.1 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.31 OAJ21629.1 - 2.9e-33 113.8 0.7 4.2e-17 62.1 0.8 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ21629.1 - 8.6e-24 83.6 0.0 2.2e-15 56.7 0.1 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ21629.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 OAJ21629.1 - 0.12 12.4 0.0 0.58 10.2 0.0 4.8 4 1 1 5 5 5 0 SLIDE Spore_III_AB PF09548.10 OAJ21629.1 - 0.21 11.7 0.0 0.21 11.7 0.0 3.3 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) BPL_N PF09825.9 OAJ21630.1 - 3.4e-95 319.3 0.0 4.3e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAJ21630.1 - 2.7e-18 66.1 0.0 4.7e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 OAJ21630.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_C PF02237.17 OAJ21630.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain ERG2_Sigma1R PF04622.12 OAJ21647.1 - 6.9e-87 290.2 0.0 9.2e-87 289.8 0.0 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein TFIIS_C PF01096.18 OAJ21647.1 - 3.9e-08 33.0 0.2 3.9e-08 33.0 0.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 OAJ21647.1 - 0.0012 18.7 0.8 0.0023 17.8 0.8 1.4 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 OAJ21647.1 - 0.0069 16.3 0.2 0.013 15.3 0.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Replicase PF03090.17 OAJ21647.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Replicase family DUF1451 PF07295.11 OAJ21647.1 - 0.21 11.6 0.2 0.42 10.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain RRM_1 PF00076.22 OAJ21648.1 - 1.1e-34 118.1 0.0 3.9e-13 49.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ21648.1 - 0.0041 16.7 0.0 0.075 12.6 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DOT1 PF08123.13 OAJ21649.1 - 2.8e-65 219.7 0.0 3.8e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pantoate_ligase PF02569.15 OAJ21650.1 - 1.1e-87 293.7 0.0 1.6e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase nec1 PF10379.9 OAJ21650.1 - 0.26 10.7 0.7 5.1 6.5 0.1 2.4 2 1 1 3 3 3 0 Virulence protein nec1 Voldacs PF03517.13 OAJ21651.1 - 0.52 10.4 6.2 0.55 10.3 4.0 2.0 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Aminotran_3 PF00202.21 OAJ21652.1 - 4e-123 411.1 0.0 5e-123 410.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAJ21652.1 - 0.018 14.4 0.0 0.064 12.5 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ21652.1 - 0.048 12.8 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Macro PF01661.21 OAJ21653.1 - 1.1e-41 141.6 0.1 1.5e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Macro domain BcrAD_BadFG PF01869.20 OAJ21654.1 - 8.3e-07 28.8 0.0 7.9e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Alph_Pro_TM PF09608.10 OAJ21656.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF3498 PF12004.8 OAJ21656.1 - 0.21 10.7 3.1 0.25 10.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Amino_oxidase PF01593.24 OAJ21658.1 - 1.5e-58 199.2 0.1 2.3e-58 198.6 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ21658.1 - 4.7e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ21658.1 - 3.4e-09 36.7 0.6 9e-08 32.1 0.6 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ21658.1 - 2.3e-05 23.8 0.1 0.012 14.9 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ21658.1 - 0.0056 17.2 0.6 5 7.7 0.1 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ21658.1 - 0.013 14.6 0.6 0.031 13.4 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 OAJ21658.1 - 0.013 15.5 0.0 0.1 12.6 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 OAJ21658.1 - 0.015 14.6 0.0 0.091 12.0 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ21658.1 - 0.033 13.4 0.4 0.073 12.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Aminotran_MocR PF12897.7 OAJ21658.1 - 0.099 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Thi4 PF01946.17 OAJ21658.1 - 0.2 10.8 0.3 0.97 8.6 0.3 2.0 1 1 0 1 1 1 0 Thi4 family GIDA PF01134.22 OAJ21658.1 - 0.28 10.2 0.0 0.48 9.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 OAJ21660.1 - 7.2e-32 110.7 36.9 1.1e-31 110.0 36.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAJ21660.1 - 1.6 6.9 15.8 0.033 12.5 2.6 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.20 OAJ21661.1 - 4.2e-20 72.5 0.6 2e-19 70.3 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ21661.1 - 1.7e-14 54.1 0.1 5.7e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Utp11 PF03998.13 OAJ21662.1 - 2.4e-54 184.9 10.4 2.9e-54 184.6 10.4 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 OAJ21662.1 - 0.14 11.5 0.7 0.24 10.7 0.4 1.4 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 ABC1 PF03109.16 OAJ21663.1 - 7.6e-21 74.5 0.0 2.7e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 ABC1 family IF-2B PF01008.17 OAJ21665.1 - 1.8e-61 207.8 0.0 2.3e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Period_C PF12114.8 OAJ21665.1 - 6 6.4 6.3 26 4.3 2.1 2.3 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Sugar_tr PF00083.24 OAJ21666.1 - 5.2e-69 233.3 16.9 6.1e-67 226.4 12.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ21666.1 - 8e-16 57.9 17.7 8e-16 57.9 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SCP2 PF02036.17 OAJ21667.1 - 1.9e-26 92.5 1.4 2.2e-26 92.3 1.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ21667.1 - 0.00022 21.5 0.4 0.00028 21.2 0.4 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Albumin_I_a PF16720.5 OAJ21667.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Albumin I chain a DSPc PF00782.20 OAJ21668.1 - 6.4e-27 94.0 0.0 2.8e-20 72.5 0.0 3.3 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ21668.1 - 0.0028 17.3 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Asp PF00026.23 OAJ21669.1 - 7.6e-39 134.0 0.0 3.6e-38 131.7 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21669.1 - 1.3e-14 54.9 0.8 5.8e-14 52.7 0.3 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ21669.1 - 0.085 13.5 0.1 11 6.7 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease OMPdecase PF00215.24 OAJ21671.1 - 3.2e-73 246.0 0.1 4.1e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2508 PF10704.9 OAJ21671.1 - 0.11 12.7 1.0 0.53 10.5 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) Elf1 PF05129.13 OAJ21672.1 - 1.1e-25 89.4 0.6 1.3e-25 89.2 0.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like FdhE PF04216.12 OAJ21672.1 - 0.082 12.8 0.7 0.11 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-Sec23_Sec24 PF04810.15 OAJ21672.1 - 0.28 11.3 3.6 0.71 10.0 3.6 1.7 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger VPS9 PF02204.18 OAJ21673.1 - 4.2e-31 107.3 0.1 7.3e-31 106.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAJ21673.1 - 1.1e-11 44.8 0.0 3.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) SNARE PF05739.19 OAJ21673.1 - 0.0046 16.9 0.2 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 SNARE domain Thg1 PF04446.12 OAJ21674.1 - 1.3e-48 164.1 0.0 2.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAJ21674.1 - 9.4e-42 142.0 1.0 2.3e-41 140.8 1.0 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain CPSF73-100_C PF11718.8 OAJ21675.1 - 1.3e-55 188.3 1.8 2.3e-55 187.5 0.3 2.1 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAJ21675.1 - 1.4e-29 102.6 0.0 2.9e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OAJ21675.1 - 8.1e-20 71.1 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OAJ21675.1 - 1.4e-18 67.6 6.2 1.3e-17 64.4 0.2 3.0 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OAJ21675.1 - 5.4e-16 58.3 0.2 1.1e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OAJ21675.1 - 1.5e-07 31.1 2.4 3.6e-07 29.9 0.3 2.5 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ21675.1 - 2e-07 31.0 0.1 7.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Ost5 PF05251.12 OAJ21676.1 - 2e-17 63.2 6.4 2.6e-17 62.8 6.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 ArfGap PF01412.18 OAJ21677.1 - 6.5e-40 135.9 0.2 6.5e-40 135.9 0.2 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AIF_C PF14721.6 OAJ21677.1 - 0.0013 19.1 3.2 0.0013 19.1 3.2 2.2 2 1 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Med24_N PF11277.8 OAJ21677.1 - 0.034 12.2 2.2 0.053 11.6 2.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF4407 PF14362.6 OAJ21677.1 - 0.16 11.3 8.6 0.29 10.4 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GATA PF00320.27 OAJ21677.1 - 0.64 9.7 2.7 1.1 8.9 2.7 1.4 1 0 0 1 1 1 0 GATA zinc finger EPL1 PF10513.9 OAJ21677.1 - 1.1 9.6 17.5 0.27 11.6 8.7 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like SpoIIIAH PF12685.7 OAJ21677.1 - 3.3 7.5 18.1 9.3 6.0 18.1 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF572 PF04502.13 OAJ21677.1 - 6.7 6.2 17.6 0.35 10.4 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) EMC3_TMCO1 PF01956.16 OAJ21677.1 - 8.2 6.1 11.3 14 5.4 11.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Phage_GPO PF05929.11 OAJ21677.1 - 8.8 5.9 14.7 18 4.8 14.7 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NUDIX PF00293.28 OAJ21678.1 - 3.1e-06 27.3 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 OAJ21679.1 - 5.4e-06 26.0 0.0 4.8e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OAJ21679.1 - 0.00013 22.0 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ21679.1 - 0.00034 19.8 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 OAJ21679.1 - 0.01 15.2 1.9 0.018 14.4 1.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ21679.1 - 0.055 12.3 6.2 0.12 11.1 0.0 2.9 3 0 0 3 3 3 0 Fungal protein kinase TAL_FSA PF00923.19 OAJ21684.1 - 8.8e-98 327.2 0.4 1e-97 327.0 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Aminotran_1_2 PF00155.21 OAJ21685.1 - 4e-78 263.1 0.0 4.6e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Acetyltransf_1 PF00583.25 OAJ21686.1 - 2.9e-10 40.4 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ21686.1 - 5.9e-07 29.5 0.0 9.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ21686.1 - 1.5e-06 28.6 0.1 2.9e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ21686.1 - 0.00065 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ21686.1 - 0.014 15.5 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pre-PUA PF17832.1 OAJ21687.1 - 2.3e-24 85.9 0.0 3.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAJ21687.1 - 3e-15 55.9 0.0 4.8e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 PUA domain Cul7 PF11515.8 OAJ21687.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.7 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 ABC_membrane_2 PF06472.15 OAJ21688.1 - 1.9e-95 319.3 4.1 2.5e-95 318.9 4.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ21688.1 - 5.7e-20 72.2 0.0 2.3e-19 70.3 0.0 2.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 OAJ21688.1 - 0.00014 21.7 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ21688.1 - 0.0027 18.2 0.2 0.016 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 OAJ21688.1 - 0.016 14.7 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OAJ21688.1 - 0.043 13.7 0.3 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain DUF815 PF05673.13 OAJ21688.1 - 0.074 12.2 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 OAJ21688.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MgtE PF01769.16 OAJ21689.1 - 8.1e-33 113.4 32.1 3.9e-20 72.5 4.0 4.3 4 1 0 4 4 4 2 Divalent cation transporter PGA2 PF07543.12 OAJ21689.1 - 3.8 7.5 5.5 7.3 6.6 5.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 COG6 PF06419.11 OAJ21709.1 - 4.5e-121 405.1 0.0 1.9e-119 399.7 0.0 2.3 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4201 PF13870.6 OAJ21709.1 - 0.043 13.5 0.9 0.072 12.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3347 PF11827.8 OAJ21709.1 - 0.077 13.2 0.3 0.16 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Sec34 PF04136.15 OAJ21709.1 - 0.1 12.5 0.3 0.37 10.7 0.3 1.9 1 0 0 1 1 1 0 Sec34-like family Carb_kinase PF01256.17 OAJ21710.1 - 1.8e-54 184.8 0.0 2.3e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAJ21710.1 - 0.005 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.6 OAJ21710.1 - 0.02 14.6 1.0 0.14 11.9 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4516) RNA_pol_I_TF PF04090.12 OAJ21711.1 - 0.00039 20.0 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF92 PF01940.16 OAJ21712.1 - 7.3e-71 238.3 6.8 9e-71 238.0 6.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Sec62 PF03839.16 OAJ21714.1 - 1e-49 169.0 2.7 1.8e-49 168.2 2.7 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.9 OAJ21714.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.19 OAJ21715.1 - 1.4e-51 175.7 0.0 1.8e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ21715.1 - 5e-31 108.2 0.1 8.2e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ21715.1 - 2.7e-05 24.3 0.1 6.5e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ21715.1 - 0.00026 20.2 0.1 0.0013 17.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ21715.1 - 0.00039 19.6 0.0 0.009 15.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 OAJ21715.1 - 0.00065 19.4 0.1 0.0016 18.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ21715.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 OAJ21715.1 - 0.0022 16.6 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox_3 PF13738.6 OAJ21715.1 - 0.0029 16.9 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ21715.1 - 0.0075 15.4 0.0 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 OAJ21715.1 - 0.021 13.6 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 OAJ21715.1 - 0.055 12.7 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 OAJ21715.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAJ21715.1 - 0.071 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 OAJ21715.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 OAJ21715.1 - 0.15 12.6 0.1 0.29 11.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 OAJ21716.1 - 2.1e-38 132.3 0.0 5.3e-38 130.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TF_AP-2 PF03299.14 OAJ21716.1 - 0.01 15.9 0.1 0.18 11.8 0.0 2.7 3 0 0 3 3 3 1 Transcription factor AP-2 UCR_14kD PF02271.16 OAJ21717.1 - 4.2e-38 129.3 0.5 4.9e-38 129.1 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Amino_oxidase PF01593.24 OAJ21718.1 - 2.4e-23 83.2 0.4 2.6e-22 79.7 0.4 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ21718.1 - 2.8e-07 30.7 0.0 8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ21718.1 - 7.1e-06 25.8 0.3 2.3e-05 24.2 0.1 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ21718.1 - 0.00015 21.8 0.0 0.031 14.3 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 OAJ21718.1 - 0.0082 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 OAJ21718.1 - 0.028 13.7 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ21718.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ21718.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DBB PF14545.6 OAJ21718.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, Pyr_redox PF00070.27 OAJ21718.1 - 0.18 12.4 0.1 11 6.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DivIC PF04977.15 OAJ21719.1 - 0.01 15.6 2.4 0.01 15.6 2.4 2.4 2 1 1 3 3 3 0 Septum formation initiator DUF4252 PF14060.6 OAJ21719.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) DUF4407 PF14362.6 OAJ21719.1 - 0.12 11.7 12.2 0.18 11.2 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltr_RsmB-F PF01189.17 OAJ21720.1 - 9e-31 107.1 0.0 1.5e-21 77.0 0.0 3.4 3 0 0 3 3 3 3 16S rRNA methyltransferase RsmB/F ATP-synt_ab PF00006.25 OAJ21721.1 - 8.6e-72 241.2 0.0 1.4e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAJ21721.1 - 1.5e-42 144.9 0.1 2.6e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAJ21721.1 - 2.7e-17 63.0 2.2 6.7e-17 61.8 2.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ICE2 PF08426.10 OAJ21722.1 - 2.4e-52 178.4 0.0 2.3e-26 92.8 0.0 3.3 2 2 0 2 2 2 2 ICE2 ADK PF00406.22 OAJ21723.1 - 4.9e-56 189.0 0.1 5.9e-56 188.8 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ21723.1 - 3e-19 69.8 0.2 7.9e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ21723.1 - 2e-16 59.6 0.0 6.3e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAJ21723.1 - 0.00074 20.1 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ21723.1 - 0.0053 16.9 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ21723.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 OAJ21723.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ21723.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Tim17 PF02466.19 OAJ21724.1 - 0.00016 22.0 0.1 1.4 9.4 0.1 3.1 3 0 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 OAJ21724.1 - 0.025 15.2 0.1 0.082 13.5 0.1 1.9 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 UQ_con PF00179.26 OAJ21725.1 - 2.1e-46 157.1 0.0 2.4e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ21725.1 - 1.3e-05 24.9 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ21725.1 - 0.0098 16.2 0.9 0.017 15.4 0.9 1.7 1 1 0 1 1 1 1 RWD domain Melibiase_2_C PF17450.2 OAJ21727.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Succ_DH_flav_C PF02910.20 OAJ21727.1 - 0.085 12.8 0.3 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term Glyco_hyd_101C PF17451.2 OAJ21727.1 - 0.091 13.1 1.3 0.28 11.5 0.5 2.0 1 1 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Leo1 PF04004.13 OAJ21728.1 - 5.8e-41 140.1 0.4 2.4e-40 138.1 0.0 2.3 2 0 0 2 2 2 1 Leo1-like protein Abhydrolase_1 PF00561.20 OAJ21729.1 - 5.9e-18 65.4 0.1 1.5e-13 51.0 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ21729.1 - 9.9e-13 49.2 0.0 1.4e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ21729.1 - 1.2e-09 37.8 0.1 1e-08 34.7 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ21729.1 - 7.7e-05 22.5 0.6 0.00054 19.7 0.5 2.2 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 OAJ21729.1 - 0.0043 16.6 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAJ21729.1 - 0.011 15.2 0.1 0.93 8.9 0.0 2.4 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 OAJ21729.1 - 0.012 15.5 0.2 0.34 10.7 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 OAJ21729.1 - 0.026 14.1 0.0 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF4407 PF14362.6 OAJ21729.1 - 0.19 11.0 3.5 0.3 10.4 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIP PF00230.20 OAJ21730.1 - 2.6e-38 132.0 15.5 3.5e-38 131.6 15.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein adh_short PF00106.25 OAJ21731.1 - 1.1e-46 158.7 1.0 1.6e-46 158.2 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ21731.1 - 6.8e-30 104.3 1.0 9.5e-30 103.9 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ21731.1 - 8.2e-06 25.9 1.2 3.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 OAJ21731.1 - 1.6e-05 24.9 0.1 2.9e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ21731.1 - 6.8e-05 22.4 0.1 0.00014 21.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SUI1 PF01253.22 OAJ21733.1 - 2.3e-30 104.9 0.4 3.2e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 TauD PF02668.16 OAJ21734.1 - 4.5e-31 108.6 0.4 4.5e-31 108.6 0.4 2.2 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAJ21734.1 - 2e-14 54.0 0.8 4.1e-13 49.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF971) Glyco_hydro_cc PF11790.8 OAJ21735.1 - 3.5e-48 164.3 0.7 4.5e-48 163.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FAD_binding_7 PF03441.14 OAJ21736.1 - 4.1e-59 199.5 0.0 6.1e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ21736.1 - 8.8e-16 58.3 0.0 1.6e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Peptidase_C37 PF05416.12 OAJ21736.1 - 2.5 6.5 5.8 4.1 5.8 5.8 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-C2H2 PF00096.26 OAJ21737.1 - 2.3e-11 43.5 13.7 0.00066 20.0 0.0 4.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ21737.1 - 8.5e-09 35.5 15.9 0.0011 19.7 0.0 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ21737.1 - 1.2e-08 35.0 2.0 0.00014 22.1 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAJ21737.1 - 0.0045 16.9 4.0 0.12 12.4 0.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAJ21737.1 - 0.031 14.2 0.9 0.031 14.2 0.9 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 OAJ21737.1 - 1 9.7 0.0 1 9.7 0.0 4.6 4 2 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 OAJ21737.1 - 1.4 9.1 3.1 8.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYDLN_acid PF09538.10 OAJ21737.1 - 2.7 8.7 4.7 4.1 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cytochrom_B562 PF07361.11 OAJ21738.1 - 0.15 12.7 0.1 0.31 11.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome b562 Dickkopf_N PF04706.12 OAJ21740.1 - 0.13 12.8 35.4 0.083 13.4 7.6 4.1 3 1 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region EB PF01683.18 OAJ21740.1 - 0.27 11.5 28.8 0.072 13.4 1.8 3.9 2 1 1 3 3 3 0 EB module DUF5319 PF17252.2 OAJ21741.1 - 0.049 13.9 0.2 0.08 13.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5319) Pkinase PF00069.25 OAJ21743.1 - 4e-72 242.7 0.0 5.1e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21743.1 - 5.8e-35 120.8 0.0 8.2e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ21743.1 - 0.037 13.4 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAJ21743.1 - 0.074 12.0 0.0 0.45 9.4 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain BP28CT PF08146.12 OAJ21744.1 - 9.7e-36 123.0 4.5 1.4e-35 122.4 0.6 3.1 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 OAJ21744.1 - 1.9e-05 25.0 0.3 1.9e-05 25.0 0.3 4.6 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 IFRD PF05004.13 OAJ21744.1 - 0.014 14.6 14.9 0.045 12.9 1.7 4.3 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 OAJ21744.1 - 0.016 15.7 15.6 3.1 8.4 0.1 8.7 8 1 1 9 9 9 0 HEAT-like repeat UME PF08064.13 OAJ21744.1 - 0.022 14.7 1.5 68 3.5 0.0 5.0 4 0 0 4 4 4 0 UME (NUC010) domain DUF3385 PF11865.8 OAJ21744.1 - 0.06 13.2 6.6 1.9 8.3 0.1 4.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Attacin_N PF03768.15 OAJ21744.1 - 0.15 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 Attacin, N-terminal region TAN PF11640.8 OAJ21744.1 - 0.29 11.3 5.8 13 5.9 0.2 5.6 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair Fanconi_A_N PF15865.5 OAJ21744.1 - 0.55 9.6 9.0 0.027 13.9 0.4 3.3 4 0 0 4 4 4 0 Fanconi anaemia group A protein N terminus Lipocalin_2 PF08212.12 OAJ21745.1 - 3.1e-10 40.2 0.0 4.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain SH3_9 PF14604.6 OAJ21746.1 - 6.8e-09 35.4 0.0 1.5e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ21746.1 - 1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain TMEM51 PF15345.6 OAJ21746.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Syndecan PF01034.20 OAJ21746.1 - 0.13 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 OAJ21746.1 - 0.16 12.0 1.2 0.29 11.1 1.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J HAD_2 PF13419.6 OAJ21747.1 - 2e-11 44.3 0.0 4.4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ21747.1 - 8.3e-09 36.0 0.0 1e-07 32.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ21747.1 - 0.017 15.5 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TRAUB PF08164.12 OAJ21748.1 - 6.6e-23 81.0 0.5 6.4e-22 77.9 0.0 3.0 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OAJ21748.1 - 4.2e-10 40.5 3.9 4.2e-10 40.5 3.9 3.1 2 2 1 3 3 3 1 Apoptosis antagonizing transcription factor DUF2890 PF11081.8 OAJ21748.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) Lipocalin_2 PF08212.12 OAJ21749.1 - 6.2e-17 61.9 0.0 8e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain NPV_P10 PF05531.12 OAJ21750.1 - 0.33 11.4 7.7 1.4 9.4 0.0 4.0 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fasciclin PF02469.22 OAJ21751.1 - 3.3e-13 50.0 0.0 1.1e-09 38.6 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain FSA_C PF10479.9 OAJ21768.1 - 0.63 8.1 10.9 0.76 7.8 10.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MGC-24 PF05283.11 OAJ21768.1 - 1 9.8 12.3 1.8 9.0 12.3 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 OAJ21768.1 - 4.4 7.5 20.6 7.7 6.7 20.6 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Cytochrom_C1 PF02167.15 OAJ21769.1 - 1.3e-100 335.6 0.0 1.6e-100 335.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAJ21769.1 - 0.0023 18.2 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAJ21769.1 - 0.062 14.5 0.1 0.32 12.2 0.1 2.2 2 1 0 2 2 2 0 Cytochrome c DUF4148 PF13663.6 OAJ21770.1 - 0.052 13.7 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Pkinase PF00069.25 OAJ21771.1 - 5.5e-72 242.3 0.0 6.8e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21771.1 - 7.4e-46 156.5 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAJ21771.1 - 1.4e-22 79.8 0.1 3.1e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OAJ21771.1 - 6.9e-06 25.1 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ21771.1 - 0.00026 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 OAJ21771.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 OAJ21771.1 - 0.046 13.6 0.2 0.79 9.6 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ21771.1 - 0.066 12.6 1.9 1.7 7.9 0.3 2.2 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ21771.1 - 0.38 9.6 0.9 0.99 8.3 0.9 1.6 1 1 0 1 1 1 0 Haspin like kinase domain PIG-X PF08320.12 OAJ21772.1 - 9.6e-21 74.7 0.0 1.6e-10 41.2 0.0 3.0 2 1 0 2 2 2 2 PIG-X / PBN1 DarA_N PF18788.1 OAJ21772.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Defence against restriction A N-terminal Hist_deacetyl PF00850.19 OAJ21773.1 - 8.1e-39 133.9 0.0 2.5e-38 132.3 0.0 1.8 1 1 0 1 1 1 1 Histone deacetylase domain Cauli_VI PF01693.16 OAJ21774.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ank_2 PF12796.7 OAJ21775.1 - 4.5e-35 120.1 0.0 6.1e-17 62.0 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ21775.1 - 1.5e-31 108.3 0.0 5.7e-12 45.9 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ21775.1 - 1.4e-27 92.7 0.0 7.9e-06 25.8 0.0 6.2 6 1 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 OAJ21775.1 - 6.9e-27 92.7 0.0 3.9e-06 27.1 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 OAJ21775.1 - 1e-26 92.6 0.1 2.5e-10 40.4 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) AAA PF00004.29 OAJ21776.1 - 6e-18 65.5 0.0 1.5e-17 64.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ21776.1 - 1.7e-10 41.2 0.7 1e-09 38.6 0.7 2.1 1 1 0 1 1 1 1 BCS1 N terminal AAA_11 PF13086.6 OAJ21776.1 - 0.044 13.6 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ21776.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_6 PF12774.7 OAJ21776.1 - 0.22 10.4 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 OAJ21776.1 - 0.33 11.3 4.0 0.46 10.9 0.0 3.0 2 2 0 2 2 2 0 AAA ATPase domain Transket_pyr PF02779.24 OAJ21778.1 - 1.9e-61 206.8 0.0 3.7e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAJ21778.1 - 7.1e-47 159.8 0.0 1.1e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAJ21778.1 - 3.8e-35 120.8 0.0 5.8e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal CAP_GLY PF01302.25 OAJ21779.1 - 4.5e-26 90.6 1.1 7.4e-26 90.0 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAJ21779.1 - 1.1e-11 45.1 0.0 3.9e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Reprolysin_5 PF13688.6 OAJ21781.1 - 2.8e-44 151.6 5.5 2.8e-44 151.6 5.5 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAJ21781.1 - 2.3e-40 138.6 2.3 2.3e-40 138.6 2.3 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAJ21781.1 - 3.1e-40 138.0 1.2 6.4e-40 137.0 1.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAJ21781.1 - 1.2e-14 54.8 24.4 1.2e-14 54.8 24.4 4.4 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAJ21781.1 - 9.3e-11 42.3 0.0 2.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OAJ21781.1 - 3.2e-09 37.0 3.3 4.1e-07 30.1 3.3 2.9 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 OAJ21781.1 - 6.4e-06 26.4 0.1 1.5e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 OAJ21781.1 - 0.0075 16.8 10.3 0.0075 16.8 10.3 3.9 1 1 1 2 2 2 1 ADAM cysteine-rich domain FAF PF11250.8 OAJ21782.1 - 0.047 14.0 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Fantastic Four meristem regulator DUF3825 PF12873.7 OAJ21783.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Thiolase_N PF00108.23 OAJ21785.1 - 1e-78 264.3 6.5 1e-78 264.3 6.5 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ21785.1 - 1.8e-43 147.1 0.6 4.3e-43 145.9 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ21785.1 - 0.0044 16.6 3.6 0.013 15.1 0.2 2.9 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 OAJ21785.1 - 0.062 13.5 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF903 PF06004.12 OAJ21785.1 - 0.099 12.5 0.2 0.22 11.4 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Ran_BP1 PF00638.18 OAJ21786.1 - 8.6e-15 55.1 0.6 1.4e-07 31.8 0.0 2.6 3 0 0 3 3 3 2 RanBP1 domain Histone PF00125.24 OAJ21787.1 - 1.1e-49 168.1 3.9 1.3e-49 167.9 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ21787.1 - 9e-05 22.8 0.1 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OAJ21787.1 - 9.8e-05 23.0 0.8 0.0001 22.9 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OAJ21787.1 - 0.00035 20.7 0.2 0.00035 20.7 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ21787.1 - 0.002 18.4 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HisKA PF00512.25 OAJ21787.1 - 0.035 14.1 0.3 0.064 13.3 0.3 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain CENP-T_C PF15511.6 OAJ21788.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ21788.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ21788.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAJ21788.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ21788.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ21788.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Brix PF04427.18 OAJ21790.1 - 6.6e-34 117.7 0.0 9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.12 OAJ21790.1 - 0.28 9.3 31.7 0.4 8.8 31.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ21790.1 - 0.59 9.4 25.6 1.1 8.5 25.6 1.4 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 OAJ21790.1 - 0.87 9.4 10.4 1.5 8.7 10.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CobT PF06213.12 OAJ21790.1 - 1.2 8.4 23.3 2 7.7 23.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Usp PF00582.26 OAJ21790.1 - 1.9 9.0 0.0 1.9 9.0 0.0 2.6 3 0 0 3 3 3 0 Universal stress protein family Paf1 PF03985.13 OAJ21790.1 - 3 6.8 15.6 4.8 6.1 15.6 1.2 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 OAJ21790.1 - 4.9 6.5 34.6 0.081 12.3 27.2 1.8 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.13 OAJ21790.1 - 5.1 5.1 37.1 7.4 4.5 37.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Med22 PF06179.12 OAJ21791.1 - 3.5e-14 52.9 0.0 5.7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex AAA PF00004.29 OAJ21792.1 - 8.9e-20 71.5 0.1 1.7e-09 38.2 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ21792.1 - 2.2e-11 44.1 2.5 2e-10 41.0 2.5 2.2 1 1 0 1 1 1 1 BCS1 N terminal AAA_11 PF13086.6 OAJ21792.1 - 0.0036 17.1 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ21792.1 - 0.033 13.9 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ21792.1 - 0.053 13.9 4.7 0.062 13.7 0.4 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 OAJ21792.1 - 0.071 13.4 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain STE3 PF02076.15 OAJ21792.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Pheromone A receptor MFS_1 PF07690.16 OAJ21794.1 - 4e-38 131.2 33.7 4e-38 131.2 33.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ21794.1 - 4.5e-11 42.3 2.6 4.5e-11 42.3 2.6 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter WD40 PF00400.32 OAJ21795.1 - 2.6e-17 62.9 4.0 0.0073 17.1 0.1 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 OAJ21795.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Sporozoite_P67 PF05642.11 OAJ21795.1 - 1.6 6.7 9.4 5.9 4.8 0.0 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ssl1 PF04056.14 OAJ21796.1 - 1.2e-68 230.7 0.0 2.4e-68 229.8 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 OAJ21796.1 - 3.8e-16 59.1 2.9 3.8e-16 59.1 2.9 3.3 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 OAJ21796.1 - 8.8e-12 45.6 0.0 2.3e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain IBR PF01485.21 OAJ21796.1 - 0.0027 17.9 1.2 0.0027 17.9 1.2 3.1 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain VWA PF00092.28 OAJ21796.1 - 0.019 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-C4H2 PF10146.9 OAJ21796.1 - 0.098 13.0 6.6 13 6.1 0.0 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein CRA PF06589.11 OAJ21796.1 - 0.16 12.1 0.7 0.37 10.9 0.7 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zinc_ribbon_15 PF17032.5 OAJ21796.1 - 0.17 12.6 13.3 0.54 11.1 6.4 3.2 1 1 1 2 2 2 0 zinc-ribbon family Tfb4 PF03850.14 OAJ21796.1 - 0.46 9.9 7.0 4.1 6.8 6.2 2.5 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.7 OAJ21796.1 - 8.6 6.5 25.8 3 7.9 9.3 3.3 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 OAJ21797.1 - 8.8e-44 149.8 0.0 1.6e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21797.1 - 1.1e-17 64.2 0.0 1.7e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF294_C PF10335.9 OAJ21797.1 - 0.00016 21.5 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain RIO1 PF01163.22 OAJ21797.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ21797.1 - 0.0079 16.1 0.7 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ21797.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Adeno_PV PF03910.13 OAJ21797.1 - 0.6 8.8 8.9 0.96 8.1 8.9 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DAHP_synth_1 PF00793.20 OAJ21798.1 - 3.2e-98 328.0 0.0 4e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family RT_RNaseH_2 PF17919.1 OAJ21799.1 - 2.1e-30 104.7 0.0 5.7e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ21799.1 - 1.6e-27 95.9 0.0 4.1e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ21799.1 - 1.4e-21 77.1 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ21799.1 - 4.4e-14 52.7 0.0 1.4e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ21799.1 - 9e-09 35.3 0.2 1.9e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ21799.1 - 0.0011 18.7 0.0 0.0055 16.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Carn_acyltransf PF00755.20 OAJ21800.1 - 6.1e-192 639.4 0.0 7e-192 639.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YueH PF14166.6 OAJ21800.1 - 0.16 11.9 0.3 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 YueH-like protein B12D PF06522.11 OAJ21801.1 - 3.6e-18 65.1 0.0 3.9e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Mito_carr PF00153.27 OAJ21802.1 - 1e-29 102.3 5.0 4.3e-15 55.4 0.2 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Polysacc_deac_1 PF01522.21 OAJ21804.1 - 8.3e-27 93.5 0.0 1.4e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Aminotran_1_2 PF00155.21 OAJ21806.1 - 1.6e-41 142.7 0.0 2.9e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II P5CR_dimer PF14748.6 OAJ21807.1 - 5.5e-38 129.4 3.3 1.8e-37 127.7 3.3 1.9 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAJ21807.1 - 3.5e-13 50.0 0.0 1.1e-08 35.5 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent TrmK PF04816.12 OAJ21807.1 - 0.18 11.4 0.1 4.8 6.7 0.1 2.2 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Dynein_light PF01221.18 OAJ21808.1 - 8e-34 115.8 0.1 9.5e-34 115.6 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 BRF1 PF07741.13 OAJ21809.1 - 3.8 7.9 7.2 13 6.2 7.2 1.9 1 1 0 1 1 1 0 Brf1-like TBP-binding domain DEAD PF00270.29 OAJ21810.1 - 2.3e-49 167.6 0.0 3.8e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ21810.1 - 2e-26 92.5 0.1 6.7e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ21810.1 - 5.1e-19 68.3 0.0 1.4e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ21810.1 - 6.7e-08 32.7 0.0 2.7e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ21810.1 - 5.2e-05 22.6 0.0 0.00015 21.1 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase BUD22 PF09073.10 OAJ21810.1 - 0.064 12.6 53.7 0.019 14.3 14.3 3.2 3 0 0 3 3 3 0 BUD22 vWA-TerF-like PF10138.9 OAJ21811.1 - 3.3e-05 24.1 0.0 5.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 OAJ21811.1 - 0.011 16.0 0.0 0.035 14.4 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain NCE101 PF11654.8 OAJ21811.1 - 0.083 12.6 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Non-classical export protein 1 Ribosomal_S8 PF00410.19 OAJ21837.1 - 2e-12 47.2 0.0 2.9e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Asp PF00026.23 OAJ21838.1 - 2.5e-69 234.1 0.3 3.8e-69 233.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21838.1 - 5.7e-11 43.0 0.2 1.5e-08 35.1 0.2 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal URO-D PF01208.17 OAJ21839.1 - 0.14 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Hfq PF17209.3 OAJ21839.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Lum_binding PF00677.17 OAJ21840.1 - 3.7e-37 126.2 0.1 1e-18 67.1 0.2 2.3 2 0 0 2 2 2 2 Lumazine binding domain DUF410 PF04190.13 OAJ21841.1 - 7.8e-61 206.1 0.0 9.8e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Sld5 PF05916.11 OAJ21842.1 - 2.7e-06 27.8 0.0 3.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein PRP1_N PF06424.12 OAJ21843.1 - 8.4e-48 162.5 4.4 8.4e-48 162.5 4.4 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAJ21843.1 - 6.3e-28 95.1 25.6 0.0095 16.7 0.1 13.9 6 5 8 14 14 14 11 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ21843.1 - 6e-22 77.9 3.0 0.0054 17.2 0.0 7.9 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ21843.1 - 3.5e-09 37.2 13.0 0.009 16.6 1.1 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ21843.1 - 1.2e-06 28.2 0.8 63 4.0 0.0 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ21843.1 - 1.3e-06 28.4 2.3 0.12 12.5 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ21843.1 - 0.00022 21.4 0.3 2.9 8.5 0.0 6.1 9 0 0 9 9 8 1 Tetratricopeptide repeat FAT PF02259.23 OAJ21843.1 - 0.0012 18.1 13.3 0.056 12.7 1.4 4.2 2 1 1 3 3 3 2 FAT domain Suf PF05843.14 OAJ21843.1 - 0.016 15.3 0.4 2 8.3 0.0 4.2 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 OAJ21843.1 - 0.85 8.5 8.7 1.5 7.6 0.1 4.4 4 1 3 7 7 7 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 OAJ21843.1 - 3 8.7 12.3 11 6.9 0.0 6.9 7 1 0 7 7 6 0 Tetratricopeptide repeat zf-DNL PF05180.12 OAJ21844.1 - 1.4e-29 101.8 0.1 2.3e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger LRR_6 PF13516.6 OAJ21845.1 - 5.6e-05 22.9 4.8 1.9 8.7 0.1 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 OAJ21845.1 - 0.0027 18.1 1.5 1.7 9.1 0.0 4.6 4 2 0 4 4 4 1 Leucine Rich repeats (2 copies) SRP-alpha_N PF04086.13 OAJ21845.1 - 6.5 6.6 11.0 14 5.5 11.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal p450 PF00067.22 OAJ21846.1 - 4.1e-56 190.6 0.0 5.3e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAPA-1 PF04795.12 OAJ21847.1 - 2.6e-16 60.2 6.1 1.9e-08 35.0 2.9 4.6 4 3 0 4 4 4 2 PAPA-1-like conserved region Ribosomal_L30_N PF08079.12 OAJ21848.1 - 1.3e-28 99.0 16.4 1.3e-28 99.0 16.4 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAJ21848.1 - 5.5e-17 61.4 0.6 1.6e-16 59.9 0.6 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.11 OAJ21848.1 - 0.054 13.8 0.6 0.099 13.0 0.6 1.3 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus COesterase PF00135.28 OAJ21849.1 - 2.6e-89 300.4 0.2 4.3e-89 299.7 0.2 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ21849.1 - 7.7e-06 25.9 0.3 0.019 14.8 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF3419 PF11899.8 OAJ21850.1 - 1.8e-145 485.0 0.2 2.4e-145 484.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 OAJ21850.1 - 4.3e-09 37.0 0.0 7.7e-08 32.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21850.1 - 4.1e-08 33.2 0.0 4.9e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ21850.1 - 1.4e-07 32.0 0.0 1.5e-05 25.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ21850.1 - 5.9e-07 29.5 0.0 3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ21850.1 - 2.3e-06 27.1 0.0 0.00035 20.0 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAJ21850.1 - 2.8e-06 28.0 0.0 8.5e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 OAJ21850.1 - 0.021 14.3 0.0 0.053 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 OAJ21850.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Mtc PF03820.17 OAJ21852.1 - 1.1e-104 349.9 0.0 1.2e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ribosomal_L13e PF01294.18 OAJ21853.1 - 1.9e-69 233.1 7.5 2.4e-69 232.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Acetyltransf_1 PF00583.25 OAJ21854.1 - 7.8e-07 29.3 0.1 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ21854.1 - 3e-06 27.6 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ21854.1 - 2.2e-05 24.4 0.2 0.014 15.3 0.2 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ21854.1 - 0.00017 21.5 0.2 0.44 10.5 0.1 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_15 PF17013.5 OAJ21854.1 - 0.037 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_9 PF13527.7 OAJ21854.1 - 0.071 13.2 0.0 0.73 9.9 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 OAJ21854.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribonuclease PF00545.20 OAJ21855.1 - 2.5e-09 37.7 0.3 3.6e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 ribonuclease Epimerase PF01370.21 OAJ21857.1 - 4.4e-16 59.1 0.1 1.3e-15 57.6 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ21857.1 - 4.9e-14 52.0 0.0 2e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ21857.1 - 2.9e-10 39.8 0.0 2.1e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAJ21857.1 - 3.1e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ21857.1 - 8.6e-07 28.7 0.2 2.7e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAJ21857.1 - 9.8e-07 28.6 0.3 3.1e-06 26.9 0.3 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAJ21857.1 - 8.3e-06 25.1 0.0 1.8e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAJ21857.1 - 0.00026 20.5 0.4 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 OAJ21857.1 - 0.0017 17.5 0.1 0.0043 16.2 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OAJ21857.1 - 0.0026 17.7 0.3 0.13 12.2 0.3 2.4 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 OAJ21857.1 - 0.13 12.7 0.0 3 8.3 0.0 2.5 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain UFD1 PF03152.14 OAJ21858.1 - 2.7e-67 225.6 0.0 3.5e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 OAJ21858.1 - 0.14 12.4 0.0 5.2 7.3 0.0 2.7 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 OAJ21858.1 - 0.56 10.0 2.4 0.86 9.4 0.0 2.4 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 Complex1_LYR_2 PF13233.6 OAJ21859.1 - 1.1e-14 54.9 0.0 3.4e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_S21 PF01165.20 OAJ21860.1 - 7.1e-11 41.7 7.2 7.1e-11 41.7 7.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S21 3Beta_HSD PF01073.19 OAJ21861.1 - 1.9e-16 59.9 0.0 2.6e-15 56.2 0.0 2.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ21861.1 - 1.9e-12 47.2 0.3 7.7e-12 45.2 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ21861.1 - 4.8e-11 42.9 0.1 7.9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAJ21861.1 - 1.5e-09 37.4 0.2 6.9e-08 32.0 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ21861.1 - 1.9e-07 30.8 0.0 4.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAJ21861.1 - 2.1e-07 30.6 1.1 0.00043 19.8 0.2 2.7 2 1 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 OAJ21861.1 - 4.7e-07 29.6 0.1 6.7e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAJ21861.1 - 6.5e-05 22.2 0.1 0.00011 21.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 OAJ21861.1 - 0.0033 17.4 0.2 0.028 14.3 0.2 2.1 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 OAJ21861.1 - 0.0086 16.3 0.1 0.018 15.3 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAJ21861.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ham1p_like PF01725.16 OAJ21862.1 - 5.1e-59 199.3 0.0 5.8e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family NOB1_Zn_bind PF08772.11 OAJ21863.1 - 6.4e-30 103.1 1.3 1.2e-29 102.2 1.3 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAJ21863.1 - 6.1e-25 87.5 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease Nudix_N_2 PF14803.6 OAJ21863.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.11 OAJ21863.1 - 2.3 7.9 5.1 1.3 8.8 0.4 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain SRP40_C PF05022.12 OAJ21864.1 - 1.8e-29 102.4 3.4 7.5e-29 100.4 3.4 2.2 1 0 0 1 1 1 1 SRP40, C-terminal domain Ribosomal_L16 PF00252.18 OAJ21865.1 - 4.9e-42 143.1 0.0 6.1e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e UDPGT PF00201.18 OAJ21866.1 - 1.3e-08 34.2 0.0 3e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_4 PF13439.6 OAJ21866.1 - 0.013 15.5 1.5 0.045 13.7 0.5 2.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.6 OAJ21866.1 - 0.094 12.7 0.0 11 6.1 0.0 2.6 1 1 0 2 2 2 0 Glycosyl transferase 4-like Put_Phosphatase PF06888.12 OAJ21867.1 - 3.9e-50 170.4 0.0 4.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 OAJ21867.1 - 3.1e-06 27.7 0.1 6.6e-06 26.7 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ21867.1 - 0.084 13.1 0.0 2.7 8.2 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 OAJ21869.1 - 6.3e-45 153.9 0.0 5.6e-44 150.8 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OAJ21869.1 - 0.004 15.9 0.0 0.0088 14.8 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OAJ21869.1 - 0.034 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ21869.1 - 0.08 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme LSM PF01423.22 OAJ21870.1 - 5.4e-14 51.6 0.1 6.9e-14 51.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ21870.1 - 0.0061 16.7 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ21870.1 - 0.076 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain FAD_binding_1 PF00667.20 OAJ21873.1 - 3.9e-55 186.8 0.0 5.5e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 OAJ21873.1 - 2.6e-07 31.3 0.0 4.1e-06 27.4 0.0 2.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 OAJ21873.1 - 1.2e-06 28.7 0.0 3.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 OAJ21873.1 - 0.021 15.1 0.0 0.097 13.0 0.0 2.1 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II 3HCDH_N PF02737.18 OAJ21874.1 - 4.5e-41 140.7 0.2 2.2e-40 138.4 0.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ21874.1 - 5.8e-36 123.0 0.1 5e-35 120.0 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Proteasome PF00227.26 OAJ21875.1 - 1.1e-58 197.8 0.1 1.4e-58 197.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ21875.1 - 9.1e-07 28.4 6.7 1.5e-05 24.6 0.1 2.6 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature FtsZ_C PF12327.8 OAJ21875.1 - 0.068 13.5 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain AP_endonuc_2 PF01261.24 OAJ21876.1 - 3.6e-16 59.3 0.1 8.5e-07 28.6 0.0 3.0 2 1 0 2 2 2 2 Xylose isomerase-like TIM barrel Glycos_transf_2 PF00535.26 OAJ21877.1 - 3.7e-21 75.7 0.0 1.4e-19 70.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 HTH_OrfB_IS605 PF12323.8 OAJ21877.1 - 1.1e-08 34.4 0.5 2.2e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Glyco_tranf_2_3 PF13641.6 OAJ21877.1 - 1.5e-06 28.2 0.8 0.00061 19.8 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Secretin_N_2 PF07655.13 OAJ21877.1 - 0.087 13.4 1.3 4.2 8.0 1.2 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Mss4 PF04421.13 OAJ21878.1 - 3.3e-10 40.0 0.3 0.001 19.1 0.0 2.5 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.25 OAJ21878.1 - 0.00013 22.2 0.0 0.00043 20.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ21878.1 - 0.067 13.1 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ21878.1 - 0.086 13.3 0.1 0.46 11.0 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ21878.1 - 0.096 12.7 0.1 20 5.2 0.1 2.6 2 0 0 2 2 2 0 FR47-like protein Pyrid_oxidase_2 PF13883.6 OAJ21878.1 - 0.33 10.9 1.6 0.7 9.8 1.6 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Iso_dh PF00180.20 OAJ21879.1 - 3.1e-70 237.0 0.0 3.8e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_M3 PF01432.20 OAJ21880.1 - 2.4e-130 435.8 0.0 3e-130 435.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OAJ21880.1 - 0.067 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Effector protein Bacteriocin_IIc PF10439.9 OAJ21882.1 - 0.26 11.4 9.4 0.39 10.9 2.8 2.8 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide EF-hand_1 PF00036.32 OAJ21883.1 - 2.4e-18 64.2 0.1 6.9e-06 25.3 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 OAJ21883.1 - 6.2e-16 56.9 0.2 1.3e-05 24.8 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 OAJ21883.1 - 3e-14 51.7 0.1 0.0015 18.0 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 OAJ21883.1 - 3.7e-13 49.7 0.0 7.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 OAJ21883.1 - 3.5e-07 29.9 0.5 0.00067 19.4 0.0 2.8 2 2 1 3 3 3 3 EF-hand domain pair Ras PF00071.22 OAJ21884.1 - 5.6e-54 182.1 0.0 6.5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ21884.1 - 2.2e-21 76.3 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ21884.1 - 2.5e-07 30.3 0.0 4.4e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 OAJ21884.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 OAJ21884.1 - 0.14 11.9 0.0 3.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAJ21884.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SHR3_chaperone PF08229.11 OAJ21885.1 - 7.3e-37 126.2 0.0 1e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Seryl_tRNA_N PF02403.22 OAJ21885.1 - 0.42 10.9 3.5 0.53 10.5 3.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SecG PF03840.14 OAJ21885.1 - 5.5 7.1 7.5 0.32 11.1 0.6 2.3 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Mito_carr PF00153.27 OAJ21886.1 - 1.1e-53 179.2 5.7 3e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PUMA PF15826.5 OAJ21886.1 - 0.31 11.2 0.9 0.5 10.5 0.9 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Rad21_Rec8_N PF04825.13 OAJ21887.1 - 3.4e-39 133.4 0.0 6.3e-39 132.6 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ21887.1 - 1.8e-15 55.9 0.0 4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein FliG_C PF01706.16 OAJ21887.1 - 0.031 14.5 0.1 0.066 13.4 0.1 1.5 1 0 0 1 1 1 0 FliG C-terminal domain A_deaminase PF00962.22 OAJ21888.1 - 8.5e-26 91.0 0.0 2.3e-25 89.6 0.0 1.8 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 OAJ21888.1 - 4.3e-05 23.7 0.0 8.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal FTA4 PF13093.6 OAJ21888.1 - 0.078 12.9 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 F-box-like PF12937.7 OAJ21889.1 - 0.29 11.1 2.5 0.44 10.5 0.1 2.6 3 0 0 3 3 3 0 F-box-like GDP_Man_Dehyd PF16363.5 OAJ21890.1 - 7.1e-47 160.4 0.0 1.7e-41 142.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ21890.1 - 1.2e-44 152.6 0.0 2e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ21890.1 - 4e-09 35.9 0.0 6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ21890.1 - 4.5e-08 32.6 0.0 0.00033 19.9 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ21890.1 - 4.8e-08 32.4 0.1 1.1e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAJ21890.1 - 1.5e-05 24.3 0.1 0.044 12.9 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein vATP-synt_AC39 PF01992.16 OAJ21891.1 - 2.8e-107 359.1 0.0 3.1e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SQS_PSY PF00494.19 OAJ21909.1 - 3e-47 161.3 6.5 1.9e-46 158.7 6.5 2.2 1 1 0 1 1 1 1 Squalene/phytoene synthase Ras PF00071.22 OAJ21911.1 - 2.1e-56 190.0 0.3 2.7e-56 189.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ21911.1 - 1.4e-33 115.6 0.1 2e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ21911.1 - 1.1e-13 51.0 0.2 1.3e-13 50.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ21911.1 - 1.1e-05 25.1 0.2 2.8e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ21911.1 - 0.00028 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ21911.1 - 0.00081 19.5 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase HAMP PF00672.25 OAJ21912.1 - 6.6e-37 125.7 17.6 2.4e-07 31.0 0.2 9.1 8 2 1 9 9 9 6 HAMP domain HATPase_c PF02518.26 OAJ21912.1 - 3.5e-27 95.1 0.0 1.7e-26 92.9 0.0 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ21912.1 - 1.4e-25 89.7 1.2 1.6e-24 86.3 0.5 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ21912.1 - 2.5e-16 59.4 0.5 2.7e-15 56.2 0.3 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain TMF_TATA_bd PF12325.8 OAJ21912.1 - 0.045 14.0 2.6 9.5 6.5 0.0 4.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3829 PF12889.7 OAJ21912.1 - 0.65 9.4 3.8 13 5.2 0.0 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF3829) DUF3150 PF11348.8 OAJ21912.1 - 1.4 8.1 6.2 1.3 8.2 0.2 3.8 3 1 1 5 5 5 0 Protein of unknown function (DUF3150) Rab5-bind PF09311.11 OAJ21912.1 - 2.7 7.3 13.7 2 7.8 0.2 4.6 2 2 2 4 4 4 0 Rabaptin-like protein SpoIIID PF12116.8 OAJ21912.1 - 4.4 7.5 4.8 31 4.7 0.0 4.3 6 0 0 6 6 6 0 Stage III sporulation protein D Adaptin_N PF01602.20 OAJ21913.1 - 2.5e-128 428.9 3.7 3e-128 428.6 3.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ21913.1 - 1.3e-61 207.4 2.5 2.7e-59 199.8 0.5 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ21913.1 - 2.7e-15 56.5 7.7 4.1e-07 30.3 0.2 4.8 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.22 OAJ21913.1 - 1.2e-08 34.4 7.1 0.0075 16.4 0.0 5.3 7 0 0 7 7 4 2 HEAT repeat Cnd3 PF12719.7 OAJ21913.1 - 2.6e-07 30.1 0.1 0.00032 20.0 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OAJ21913.1 - 4.2e-06 26.6 3.3 0.0057 16.7 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ21913.1 - 0.00026 21.4 5.5 3.2 8.3 0.1 5.9 7 0 0 7 7 7 1 HEAT-like repeat Arm_2 PF04826.13 OAJ21913.1 - 0.0006 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like RTP1_C1 PF10363.9 OAJ21913.1 - 0.0024 18.0 1.6 0.73 10.0 0.1 3.3 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 OAJ21913.1 - 0.057 13.8 0.2 0.55 10.6 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 OAJ21913.1 - 0.2 11.2 2.7 22 4.5 0.0 3.4 3 1 0 3 3 3 0 CLASP N terminal DUF4202 PF13875.6 OAJ21914.1 - 1.2e-55 188.3 0.1 2.4e-55 187.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.12 OAJ21914.1 - 1.1e-15 58.2 0.0 2.7e-13 50.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ21914.1 - 4.5e-14 52.6 0.0 2.2e-13 50.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ21914.1 - 2.9e-11 43.9 0.0 1.1e-09 38.8 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ21914.1 - 8.2e-09 36.0 0.0 5.8e-07 30.1 0.0 3.2 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21914.1 - 2.6e-07 30.6 0.0 3.1e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ21914.1 - 0.0081 17.2 0.1 0.056 14.5 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAJ21914.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 OAJ21914.1 - 0.05 12.8 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Lipase_GDSL_2 PF13472.6 OAJ21915.1 - 0.18 12.2 0.4 0.36 11.2 0.4 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 OAJ21916.1 - 4.2e-17 62.1 45.6 4.2e-17 62.1 45.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CRAL_TRIO PF00650.20 OAJ21917.1 - 4.6e-30 104.4 0.1 7.1e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ21917.1 - 1.5e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ21917.1 - 2.8e-07 30.6 0.0 6.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NOA36 PF06524.12 OAJ21917.1 - 3.6 6.8 4.5 6.8 5.9 4.5 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 OAJ21917.1 - 3.6 5.7 4.2 4.9 5.2 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family ATP_bind_1 PF03029.17 OAJ21919.1 - 4.8e-75 252.4 0.0 5.9e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ21919.1 - 5.4e-05 23.1 0.0 0.00016 21.6 0.0 1.8 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 OAJ21919.1 - 0.0033 17.5 0.0 0.0056 16.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 OAJ21919.1 - 0.0036 16.3 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 OAJ21919.1 - 0.0076 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_30 PF13604.6 OAJ21919.1 - 0.024 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAJ21919.1 - 0.031 14.8 0.1 0.57 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ21919.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 OAJ21919.1 - 0.062 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ21919.1 - 0.063 13.4 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 OAJ21919.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CLZ PF16526.5 OAJ21919.1 - 0.12 12.7 0.1 4.5 7.7 0.0 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Bromodomain PF00439.25 OAJ21920.1 - 1.8e-20 72.8 0.2 3.5e-20 71.9 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAJ21920.1 - 8.8e-07 28.9 0.2 3.6e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.8 OAJ21921.1 - 1.1e-09 38.1 0.1 1.4e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Mito_carr PF00153.27 OAJ21922.1 - 1e-55 185.6 1.6 6.4e-19 67.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_20 PF00728.22 OAJ21923.1 - 6.8e-83 279.0 0.0 8.6e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAJ21923.1 - 2.6e-15 57.3 0.0 4.2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAJ21923.1 - 0.00067 20.4 0.1 0.0089 16.8 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 FAM104 PF15434.6 OAJ21924.1 - 0.69 10.5 0.0 0.69 10.5 0.0 3.9 3 1 0 4 4 4 0 Family 104 Mito_carr PF00153.27 OAJ21925.1 - 2.8e-64 213.1 0.5 1.6e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.22 OAJ21926.1 - 8.2e-10 38.9 10.6 0.00016 21.7 0.8 2.6 2 0 0 2 2 2 2 Rhomboid family TruB_C_2 PF16198.5 OAJ21926.1 - 0.036 14.2 0.0 4.5 7.5 0.0 2.9 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain SR-25 PF10500.9 OAJ21926.1 - 2.3 7.8 7.4 4.6 6.8 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Efg1 PF10153.9 OAJ21927.1 - 3.2e-19 69.4 3.3 3.2e-19 69.4 3.3 2.3 2 0 0 2 2 2 1 rRNA-processing protein Efg1 cwf18 PF08315.12 OAJ21928.1 - 1.3e-28 100.3 9.3 1.8e-28 99.8 9.3 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RRM_1 PF00076.22 OAJ21929.1 - 2.2e-33 113.9 0.0 3.2e-17 62.1 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ21929.1 - 0.00018 21.5 0.0 0.002 18.2 0.0 2.3 2 1 1 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 OAJ21929.1 - 0.0015 18.1 0.0 0.86 9.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAJ21929.1 - 0.038 14.2 0.0 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 OAJ21929.1 - 0.06 13.0 0.2 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain AA_permease_2 PF13520.6 OAJ21930.1 - 1.1e-76 258.4 36.9 1.4e-76 258.0 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease Metallopep PF12044.8 OAJ21931.1 - 1.7e-88 297.1 0.0 8.9e-71 238.7 0.0 3.0 2 1 0 2 2 2 2 Putative peptidase family Jacalin PF01419.17 OAJ21931.1 - 2e-24 86.0 0.0 0.0036 17.2 0.0 6.7 6 0 0 6 6 6 6 Jacalin-like lectin domain Peptidase_M66 PF10462.9 OAJ21931.1 - 0.0036 16.3 0.3 0.0088 15.0 0.2 1.6 2 0 0 2 2 2 1 Peptidase M66 UPF0270 PF06794.12 OAJ21931.1 - 0.15 12.1 0.3 3.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Methyltransf_11 PF08241.12 OAJ21932.1 - 3.9e-11 43.5 0.0 9.1e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ21932.1 - 1.7e-09 38.2 0.0 4.5e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ21932.1 - 4.2e-07 30.6 0.0 8.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ21932.1 - 7.4e-05 22.6 0.0 0.00026 20.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ21932.1 - 9.3e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAJ21932.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ21932.1 - 0.0088 15.6 0.0 0.061 12.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase small domain Ank_2 PF12796.7 OAJ21933.1 - 3.4e-13 50.0 0.7 2.5e-11 44.0 0.3 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ21933.1 - 6e-12 45.8 1.6 3.9e-09 36.9 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ21933.1 - 4.1e-11 42.1 0.2 0.00012 22.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ21933.1 - 1.4e-09 38.0 0.8 2.2e-05 24.6 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ21933.1 - 3.8e-08 33.4 0.4 0.00012 22.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Rtf2 PF04641.12 OAJ21933.1 - 0.07 12.5 3.8 0.41 10.0 4.5 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger Borrelia_P83 PF05262.11 OAJ21933.1 - 0.083 11.4 5.2 0.092 11.2 5.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4337 PF14235.6 OAJ21933.1 - 8 6.5 8.0 17 5.5 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) tRNA-synt_2b PF00587.25 OAJ21934.1 - 2.5e-29 102.5 0.0 5.1e-29 101.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ21934.1 - 0.00056 20.0 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Kinesin PF00225.23 OAJ21935.1 - 3.8e-109 364.6 0.0 6.7e-109 363.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 OAJ21935.1 - 6.3e-42 143.8 0.7 8.3e-33 114.0 0.6 2.9 2 0 0 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 OAJ21935.1 - 1.1e-33 117.1 0.0 2.7e-33 115.8 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 OAJ21935.1 - 2.8e-25 89.0 0.0 6.3e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 OAJ21935.1 - 8.8e-16 58.3 0.1 2.8e-15 56.7 0.1 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 OAJ21935.1 - 2e-09 37.7 0.1 6.1e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 OAJ21935.1 - 6.5e-06 26.4 0.0 2.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 OAJ21935.1 - 0.096 13.1 0.3 0.33 11.4 0.3 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain LSM PF01423.22 OAJ21936.1 - 6.2e-16 57.9 0.0 1.8e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 LSM domain DUF3510 PF12022.8 OAJ21936.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) GRP PF07172.11 OAJ21936.1 - 2.1 9.1 27.6 3.1 8.6 27.6 1.2 1 0 0 1 1 1 0 Glycine rich protein family ATP-synt PF00231.19 OAJ21937.1 - 4.7e-74 249.6 2.4 5.3e-74 249.4 2.4 1.0 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.10 OAJ21937.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_transf_8 PF01501.20 OAJ21938.1 - 4.3e-19 69.1 0.0 2.5e-16 60.0 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAJ21938.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Nodulin_late PF07127.11 OAJ21939.1 - 3 8.2 6.0 1.6 9.1 0.2 2.5 3 0 0 3 3 3 0 Late nodulin protein Pyrid_ox_like PF16242.5 OAJ21940.1 - 9.6e-30 103.1 0.3 1.4e-29 102.6 0.3 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAJ21940.1 - 2.6e-11 43.6 0.0 3.5e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Dppa2_A PF14049.6 OAJ21940.1 - 0.0045 17.1 0.1 0.012 15.7 0.1 1.7 2 0 0 2 2 2 1 Dppa2/4 conserved region in higher vertebrates DUF374 PF04028.13 OAJ21940.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) eIF-5_eIF-2B PF01873.17 OAJ21941.1 - 2.5e-40 137.0 0.2 4e-40 136.3 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OAJ21941.1 - 0.00021 20.7 0.2 0.00039 19.9 0.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 OAJ21941.1 - 0.5 10.7 0.2 0.5 10.7 0.2 2.8 2 1 1 3 3 3 0 Archaeal TRASH domain PITH PF06201.13 OAJ21942.1 - 2.9e-35 121.7 0.0 3.5e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Mito_carr PF00153.27 OAJ21943.1 - 2.7e-30 104.1 3.4 2.1e-15 56.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_10 PF13374.6 OAJ21944.1 - 7.5e-67 219.6 115.7 1.7e-06 27.7 2.8 21.4 22 0 0 22 22 22 18 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ21944.1 - 4.7e-42 142.2 111.6 2.1e-05 24.7 7.0 19.2 11 8 5 17 17 17 14 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ21944.1 - 9.2e-20 69.1 55.1 0.065 13.4 0.3 18.3 19 0 0 19 19 19 8 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ21944.1 - 2.3e-10 40.7 39.1 0.0014 18.7 0.6 8.0 5 3 2 8 8 8 5 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 OAJ21944.1 - 1.1e-08 34.5 27.5 0.15 11.9 0.2 14.0 16 0 0 16 16 16 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ21944.1 - 3.4e-07 30.0 46.2 1.3 9.4 0.1 15.1 18 0 0 18 18 14 3 Tetratricopeptide repeat DUF4936 PF16290.5 OAJ21944.1 - 0.012 16.3 10.6 0.35 11.6 0.0 6.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4936) Rapsyn_N PF10579.9 OAJ21944.1 - 0.013 15.5 0.1 37 4.5 0.0 5.6 6 0 0 6 6 5 0 Rapsyn N-terminal myristoylation and linker region Pkinase_fungal PF17667.1 OAJ21944.1 - 0.013 14.3 14.7 2.8 6.6 0.4 7.9 7 3 0 8 8 8 0 Fungal protein kinase Hydant_A_N PF05378.13 OAJ21944.1 - 0.032 13.9 3.1 4.5 6.9 0.1 4.7 5 1 2 7 7 7 0 Hydantoinase/oxoprolinase N-terminal region Prefoldin_2 PF01920.20 OAJ21944.1 - 0.035 14.0 14.0 2.1 8.3 0.0 6.4 7 1 0 7 7 7 0 Prefoldin subunit TPR_4 PF07721.14 OAJ21944.1 - 0.072 13.8 31.5 1.5 9.6 0.5 11.6 10 0 0 10 10 10 0 Tetratricopeptide repeat Desmo_N PF06771.11 OAJ21944.1 - 0.15 12.4 0.1 66 4.0 0.0 4.3 3 1 1 4 4 3 0 Viral Desmoplakin N-terminus Syntaxin-6_N PF09177.11 OAJ21944.1 - 1.4 9.5 9.3 6.6 7.4 0.1 5.3 5 1 0 5 5 5 0 Syntaxin 6, N-terminal ANAPC5 PF12862.7 OAJ21944.1 - 3 8.0 31.3 21 5.3 0.0 11.6 7 4 6 13 13 13 0 Anaphase-promoting complex subunit 5 PSD2 PF07624.11 OAJ21944.1 - 4.2 7.2 17.4 1.3 8.8 0.1 6.9 6 2 1 8 8 8 0 Protein of unknown function (DUF1585) SQHop_cyclase_N PF13249.6 OAJ21945.1 - 2.6e-46 158.0 0.1 5e-38 130.9 0.0 4.2 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 OAJ21945.1 - 1.4e-45 155.8 3.4 3.1e-44 151.4 0.5 2.6 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 OAJ21945.1 - 4.4e-29 99.9 10.6 3.7e-08 32.9 0.0 6.7 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAJ21945.1 - 1.6e-06 27.4 1.5 0.016 14.2 0.1 3.8 1 1 2 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 OAJ21945.1 - 0.0044 16.4 0.8 2.7 7.2 0.0 4.0 3 1 1 5 5 5 1 Pectic acid lyase WD40 PF00400.32 OAJ21946.1 - 2e-29 101.2 16.9 4.5e-06 27.3 0.7 9.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ21946.1 - 3.3e-09 36.9 0.8 0.0036 17.6 0.0 5.7 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ21946.1 - 0.0015 17.5 0.0 0.44 9.5 0.0 3.7 5 0 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PA_decarbox PF05870.11 OAJ21947.1 - 4.7e-23 81.5 0.9 5.3e-23 81.4 0.9 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF_C PF17409.2 OAJ21947.1 - 1e-08 34.8 1.0 1.4e-08 34.4 0.9 1.3 1 1 0 1 1 1 1 MoaF C-terminal domain MoaF PF10703.9 OAJ21947.1 - 2.7e-05 24.0 0.1 4.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 MoaF N-terminal domain Orn_DAP_Arg_deC PF00278.22 OAJ21947.1 - 0.03 14.5 0.0 0.036 14.3 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 2-Hacid_dh_C PF02826.19 OAJ21948.1 - 2.6e-35 121.4 0.0 1.1e-33 116.1 0.0 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ21948.1 - 0.00075 19.2 0.0 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 OAJ21948.1 - 0.00093 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 OAJ21948.1 - 0.074 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Proteasome PF00227.26 OAJ21949.1 - 4.7e-33 114.3 0.0 7.3e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit CK2S PF15011.6 OAJ21950.1 - 0.082 12.8 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Casein Kinase 2 substrate tRNA-synt_1 PF00133.22 OAJ21951.1 - 9.9e-223 740.7 0.0 1.2e-222 740.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ21951.1 - 9.1e-22 77.7 0.0 1.8e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ21951.1 - 1.8e-12 46.7 1.7 0.00027 19.8 0.3 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAJ21951.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Phosducin PF02114.16 OAJ21952.1 - 1.9e-18 66.4 0.8 2.9e-08 33.0 0.0 3.2 3 0 0 3 3 3 3 Phosducin zf-C2H2_jaz PF12171.8 OAJ21953.1 - 2.6e-07 30.8 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ21953.1 - 4.5e-05 23.7 0.2 7.2e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 OAJ21953.1 - 0.0003 20.8 0.4 0.00055 20.0 0.1 1.6 2 0 0 2 2 2 1 DBF zinc finger zf-C2H2_4 PF13894.6 OAJ21953.1 - 0.061 14.2 0.1 0.12 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger PsbP PF01789.16 OAJ21953.1 - 0.089 12.9 0.4 0.19 11.8 0.3 1.5 1 1 0 1 1 1 0 PsbP UNC-79 PF14776.6 OAJ21953.1 - 0.22 10.2 0.7 0.3 9.8 0.7 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ku_C PF03730.14 OAJ21953.1 - 2.6 8.8 11.6 1.8 9.3 1.5 2.4 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm PIG-L PF02585.17 OAJ21954.1 - 3.2e-24 86.0 0.0 4.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CENP-B_dimeris PF09026.10 OAJ21956.1 - 0.16 12.3 2.8 0.3 11.5 2.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ21956.1 - 0.9 8.8 3.8 1.4 8.2 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein NPR3 PF03666.13 OAJ21956.1 - 1.6 7.5 4.1 2.2 7.0 4.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PBP1_TM PF14812.6 OAJ21956.1 - 5 7.6 5.9 14 6.1 5.9 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Anoctamin PF04547.12 OAJ21970.1 - 5.7e-97 325.4 0.0 7e-97 325.1 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel LapA_dom PF06305.11 OAJ21970.1 - 4.7 7.1 8.5 0.39 10.6 1.1 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain FPN1 PF06963.12 OAJ21971.1 - 1.9e-118 395.8 2.5 7.1e-102 341.2 1.2 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Kinesin PF00225.23 OAJ21972.1 - 8.9e-93 310.8 0.1 2.3e-92 309.5 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ21972.1 - 1.6e-48 164.4 0.0 3.6e-48 163.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Macoilin PF09726.9 OAJ21972.1 - 0.0018 16.9 11.8 0.0018 16.9 11.8 1.6 2 0 0 2 2 2 1 Macoilin family HET-S PF17108.5 OAJ21972.1 - 0.16 11.8 2.0 0.34 10.7 0.3 2.5 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic CENP-K PF11802.8 OAJ21972.1 - 0.26 10.8 15.7 0.3 10.6 14.0 1.8 2 0 0 2 2 2 0 Centromere-associated protein K AAA_13 PF13166.6 OAJ21972.1 - 1.3 7.5 14.5 2.7 6.6 14.5 1.4 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 OAJ21972.1 - 6.7 6.0 14.2 15 4.9 14.2 1.5 1 0 0 1 1 1 0 FAM76 protein GST_C_6 PF17171.4 OAJ21974.1 - 0.00017 21.3 0.0 0.025 14.4 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain p47_phox_C PF08944.11 OAJ21974.1 - 1 8.8 8.6 0.28 10.6 1.5 2.4 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain YEATS PF03366.16 OAJ21975.1 - 1.8e-38 130.4 0.0 2.9e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 YEATS family DUF2570 PF10828.8 OAJ21975.1 - 0.75 9.6 3.2 1.4 8.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) SAC3_GANP PF03399.16 OAJ21976.1 - 5.9e-25 88.2 6.3 6.2e-23 81.6 6.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAJ21976.1 - 0.00071 19.6 0.2 0.0019 18.2 0.2 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TPR_MalT PF17874.1 OAJ21976.1 - 0.14 11.5 1.4 0.14 11.5 0.1 1.5 2 0 0 2 2 2 0 MalT-like TPR region DUF2721 PF11026.8 OAJ21977.1 - 0.017 15.0 0.5 0.042 13.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) HBS1_N PF08938.10 OAJ21977.1 - 0.94 9.8 6.2 0.77 10.1 3.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus Actin PF00022.19 OAJ21979.1 - 2.2e-18 66.1 0.0 2.9e-10 39.3 0.0 3.5 3 1 0 3 3 3 3 Actin Actin_micro PF17003.5 OAJ21979.1 - 1.6e-10 40.8 0.0 8.3e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 Putative actin-like family Med9 PF07544.13 OAJ21980.1 - 0.036 14.1 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 OEP PF02321.18 OAJ21980.1 - 0.044 13.6 0.4 0.044 13.6 0.4 2.1 1 1 1 2 2 2 0 Outer membrane efflux protein Metal_resist PF13801.6 OAJ21980.1 - 0.046 13.9 7.4 0.11 12.7 2.2 2.4 2 0 0 2 2 2 0 Heavy-metal resistance PRP38 PF03371.15 OAJ21981.1 - 7.5e-59 198.5 0.2 9.2e-59 198.2 0.2 1.1 1 0 0 1 1 1 1 PRP38 family FMO-like PF00743.19 OAJ21982.1 - 2.1e-19 69.4 0.0 1.2e-13 50.4 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ21982.1 - 8.1e-10 38.4 0.0 4.9e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ21982.1 - 1.3e-07 31.2 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ21982.1 - 4.2e-05 23.3 0.2 0.0016 18.1 0.0 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ21982.1 - 7.3e-05 22.1 0.0 0.0091 15.2 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ21982.1 - 0.00059 19.9 3.0 0.0016 18.5 0.3 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ21982.1 - 0.0014 18.8 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAJ21982.1 - 0.04 14.0 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 OAJ21982.1 - 0.16 12.4 0.1 3.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Prothymosin PF03247.14 OAJ21982.1 - 0.83 10.1 18.8 0.14 12.6 11.7 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family RNA_pol_3_Rpc31 PF11705.8 OAJ21982.1 - 2.9 8.1 10.0 0.57 10.4 5.7 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_Rpc4 PF05132.14 OAJ21983.1 - 5.2e-25 88.6 0.0 5.2e-25 88.6 0.0 3.7 4 0 0 4 4 4 1 RNA polymerase III RPC4 Leo1 PF04004.13 OAJ21983.1 - 0.0096 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 Leo1-like protein ABC_membrane PF00664.23 OAJ21984.1 - 2.3e-35 122.6 2.9 2.3e-35 122.6 2.9 2.2 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ21984.1 - 4.1e-33 114.8 0.0 9.4e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAJ21984.1 - 1.7e-05 24.4 0.2 0.00047 19.7 0.2 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ21984.1 - 9.4e-05 22.9 0.2 0.00032 21.1 0.2 1.9 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ21984.1 - 0.0017 18.3 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 OAJ21984.1 - 0.0022 17.7 1.4 0.2 11.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ21984.1 - 0.0023 18.2 0.0 0.01 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 OAJ21984.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ21984.1 - 0.023 14.4 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SelK_SelG PF10961.8 OAJ21984.1 - 0.08 13.6 0.3 0.4 11.3 0.0 2.4 1 1 1 2 2 2 0 Selenoprotein SelK_SelG AAA_29 PF13555.6 OAJ21984.1 - 0.1 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 OAJ21984.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Piezo_RRas_bdg PF12166.8 OAJ21984.1 - 0.26 10.5 2.2 1.7 7.8 0.1 2.6 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain HpcH_HpaI PF03328.14 OAJ21985.1 - 1e-37 129.4 0.2 2.7e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAJ21985.1 - 9.2e-09 34.9 0.0 0.00027 20.2 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Apt1 PF10351.9 OAJ21985.1 - 0.34 9.7 10.3 0.45 9.3 8.9 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain ABM PF03992.16 OAJ21987.1 - 0.0013 18.8 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Asp PF00026.23 OAJ21988.1 - 6.3e-49 167.1 0.5 2.4e-48 165.2 0.5 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21988.1 - 2.1e-07 31.3 3.4 0.00074 19.8 2.4 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 OAJ21988.1 - 0.0061 17.1 0.8 0.56 10.8 0.1 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAJ21988.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.23 OAJ21989.1 - 7e-51 173.5 4.9 3.2e-50 171.3 4.9 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ21989.1 - 4.2e-07 30.4 3.9 0.0094 16.2 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ21989.1 - 0.0043 16.8 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAJ21989.1 - 0.0092 16.5 0.6 0.17 12.5 0.2 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ21989.1 - 0.015 16.0 1.6 0.42 11.3 0.7 2.5 2 0 0 2 2 2 0 Aspartyl protease Cyclin PF08613.11 OAJ21991.1 - 1.1e-34 120.2 14.7 4.9e-23 82.3 0.0 3.7 3 1 0 3 3 3 2 Cyclin Neur_chan_memb PF02932.16 OAJ21991.1 - 2.1 8.4 9.5 3.5 7.6 5.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 OAJ21991.1 - 3.6 5.4 6.0 5.4 4.8 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 OAJ21991.1 - 4.4 6.4 6.5 7.5 5.6 6.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TFIIA PF03153.13 OAJ21991.1 - 6.2 6.7 40.2 3 7.7 33.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PKD_channel PF08016.12 OAJ21992.1 - 0.037 12.7 0.1 0.037 12.7 0.1 2.5 2 1 0 2 2 2 0 Polycystin cation channel NOA36 PF06524.12 OAJ21992.1 - 2 7.7 11.9 3.3 7.0 11.9 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ21992.1 - 3.7 7.2 11.4 6.3 6.5 11.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FOXP-CC PF16159.5 OAJ21993.1 - 0.018 15.6 0.3 0.034 14.8 0.3 1.4 1 0 0 1 1 1 0 FOXP coiled-coil domain G-gamma PF00631.22 OAJ21994.1 - 2.4e-21 75.5 0.0 2.7e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain AAA PF00004.29 OAJ21995.1 - 5.1e-40 137.0 0.0 1.3e-39 135.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ21995.1 - 1.9e-19 69.3 0.0 4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ21995.1 - 8.6e-10 38.3 0.0 2.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ21995.1 - 8e-05 23.1 0.2 0.02 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ21995.1 - 0.00074 19.5 1.0 0.0066 16.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ21995.1 - 0.00099 19.4 0.3 0.07 13.4 0.3 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ21995.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OAJ21995.1 - 0.0015 18.4 0.3 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAJ21995.1 - 0.0022 18.2 2.6 0.0076 16.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 OAJ21995.1 - 0.0038 16.7 0.0 0.033 13.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 OAJ21995.1 - 0.012 15.1 0.1 0.052 12.9 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ21995.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ21995.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAJ21995.1 - 0.069 12.9 0.1 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 OAJ21995.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CENP-H PF05837.12 OAJ21995.1 - 0.15 12.5 2.2 0.38 11.2 2.2 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2183 PF09949.9 OAJ21996.1 - 1.6e-24 86.1 0.0 3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 OAJ21996.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Pyridoxal_deC PF00282.19 OAJ21998.1 - 1.3e-90 303.8 0.0 5.4e-61 206.4 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAJ21998.1 - 0.063 12.6 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase PI3_PI4_kinase PF00454.27 OAJ21999.1 - 1.1e-50 172.9 0.0 1.7e-50 172.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAJ21999.1 - 5.1e-32 111.1 1.4 1.8e-31 109.3 1.4 2.1 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAJ21999.1 - 2.8e-09 36.6 0.0 6.8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain CENP-Q PF13094.6 OAJ21999.1 - 0.42 10.8 4.3 1.8 8.7 3.6 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HEAT_2 PF13646.6 OAJ21999.1 - 0.96 9.9 4.9 1.4 9.4 0.1 4.0 3 0 0 3 3 3 0 HEAT repeats Aminotran_1_2 PF00155.21 OAJ22000.1 - 2.5e-32 112.5 0.0 3e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2408 PF10303.9 OAJ22001.1 - 1.9e-51 174.2 1.4 2.2e-36 125.4 0.0 4.7 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) CDC45 PF02724.14 OAJ22001.1 - 0.018 13.4 2.7 0.034 12.4 2.7 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 OAJ22001.1 - 3.2 8.0 12.2 0.55 10.4 7.7 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ22001.1 - 4.2 5.5 10.9 9.1 4.3 10.9 1.5 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 OAJ22001.1 - 4.5 7.7 9.8 8.7 6.8 9.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Y_phosphatase PF00102.27 OAJ22002.1 - 1.5e-52 178.5 0.6 1e-44 152.9 0.0 3.1 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAJ22002.1 - 0.0078 16.7 0.0 0.075 13.6 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 OAJ22002.1 - 0.027 14.5 0.0 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.20 OAJ22002.1 - 0.033 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PLDc_2 PF13091.6 OAJ22003.1 - 1.5e-15 57.3 0.0 3.8e-07 30.1 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAJ22003.1 - 7.8e-15 54.4 1.4 1e-07 31.8 0.4 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Pyridoxal_deC PF00282.19 OAJ22005.1 - 2.6e-96 322.6 0.0 1.8e-64 217.8 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 OAJ22005.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II IF-2B PF01008.17 OAJ22006.1 - 2.9e-67 226.8 0.0 4.4e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIIA PF03153.13 OAJ22006.1 - 0.27 11.2 33.6 0.4 10.6 33.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 OAJ22006.1 - 0.42 10.5 16.2 0.66 9.9 16.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Lin-8 PF03353.15 OAJ22006.1 - 1.6 8.2 10.4 2.5 7.6 10.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 OAJ22006.1 - 4.2 5.5 25.0 5.6 5.1 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.19 OAJ22006.1 - 4.9 7.0 18.1 7 6.4 18.1 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 OAJ22006.1 - 6.7 5.4 17.1 9.9 4.8 17.1 1.2 1 0 0 1 1 1 0 Presenilin DUF3188 PF11384.8 OAJ22007.1 - 0.018 14.7 2.2 0.04 13.6 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF4381 PF14316.6 OAJ22007.1 - 0.028 14.7 1.9 0.032 14.5 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) PgaD PF13994.6 OAJ22007.1 - 0.081 13.0 0.2 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein CcmH PF03918.14 OAJ22007.1 - 0.13 11.5 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Phage_holin_5_2 PF16079.5 OAJ22007.1 - 0.17 12.3 0.1 0.34 11.3 0.1 1.4 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Arv1 PF04161.13 OAJ22008.1 - 3.8e-23 82.7 4.6 7.4e-20 72.0 0.4 2.3 2 0 0 2 2 2 2 Arv1-like family SMC_N PF02463.19 OAJ22009.1 - 4.7e-25 88.3 3.5 1.3e-24 86.9 3.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OAJ22009.1 - 2.3e-10 40.8 15.6 2.3e-10 40.8 15.6 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 OAJ22009.1 - 9.8e-06 26.2 45.4 9.8e-06 26.2 45.4 6.2 3 2 1 4 4 3 1 AAA domain DUF3958 PF13125.6 OAJ22009.1 - 0.00055 20.1 0.8 0.00055 20.1 0.8 7.0 5 2 1 6 6 5 1 Protein of unknown function (DUF3958) AAA_29 PF13555.6 OAJ22009.1 - 0.0029 17.3 0.1 0.0067 16.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 OAJ22009.1 - 0.0041 17.1 9.4 0.0041 17.1 9.4 6.9 4 2 3 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcCD_C PF13558.6 OAJ22009.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 OAJ22009.1 - 0.012 15.4 16.7 0.043 13.6 0.4 4.2 3 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system APG6_N PF17675.1 OAJ22009.1 - 0.013 16.0 14.6 0.013 16.0 14.6 7.4 4 2 3 7 7 7 0 Apg6 coiled-coil region EzrA PF06160.12 OAJ22009.1 - 3.9 5.6 73.4 0.13 10.4 11.4 4.8 2 2 2 4 4 4 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 OAJ22009.1 - 8.8 6.4 50.6 3 7.9 1.7 7.4 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) Rpr2 PF04032.16 OAJ22010.1 - 3.3e-12 46.5 0.3 6.4e-12 45.6 0.3 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pet100 PF09803.9 OAJ22010.1 - 0.52 10.9 2.0 0.86 10.2 2.0 1.3 1 0 0 1 1 1 0 Pet100 V-ATPase_H_N PF03224.14 OAJ22011.1 - 6.5e-84 281.9 0.0 1.4e-83 280.8 0.0 1.6 1 1 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAJ22011.1 - 3.9e-31 107.6 0.0 1.4e-30 105.8 0.0 2.1 1 0 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 OAJ22011.1 - 0.038 14.2 0.0 2.9 8.4 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat DUF1180 PF06679.12 OAJ22011.1 - 8.6 6.7 7.8 5.6 7.3 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) OrsD PF12013.8 OAJ22012.1 - 4e-20 72.4 1.9 1.6e-10 41.4 0.3 4.6 3 1 0 4 4 4 2 Orsellinic acid/F9775 biosynthesis cluster protein D HLH PF00010.26 OAJ22013.1 - 6.7e-05 22.8 0.0 0.00021 21.2 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fungal_trans PF04082.18 OAJ22030.1 - 4.3e-06 25.9 0.0 8.6e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Proteasome PF00227.26 OAJ22031.1 - 3.3e-38 131.1 0.0 3.7e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane PF00664.23 OAJ22033.1 - 5.9e-114 380.4 24.7 2.1e-60 204.7 12.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ22033.1 - 5.7e-68 227.7 2.7 4e-33 114.8 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 OAJ22033.1 - 2.4e-16 59.9 6.0 5e-07 29.4 1.2 4.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAJ22033.1 - 2.5e-12 46.3 0.3 0.0004 19.3 0.1 4.3 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAJ22033.1 - 5.5e-08 32.4 0.4 0.0028 17.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ22033.1 - 7.9e-08 32.7 0.2 0.06 13.6 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 OAJ22033.1 - 7.4e-07 29.3 0.1 0.14 12.0 0.0 3.5 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ22033.1 - 1.1e-06 28.6 0.3 0.059 13.1 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 OAJ22033.1 - 2e-06 28.3 0.8 0.021 15.2 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAJ22033.1 - 3.6e-06 27.6 6.0 0.31 11.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 OAJ22033.1 - 1.1e-05 25.4 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 OAJ22033.1 - 2.3e-05 24.1 0.0 0.041 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 OAJ22033.1 - 9.2e-05 22.2 0.4 0.44 10.2 0.2 3.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAJ22033.1 - 0.00013 21.4 0.0 0.11 11.7 0.0 3.0 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 OAJ22033.1 - 0.00015 22.2 0.2 0.73 10.3 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OAJ22033.1 - 0.00018 21.7 3.5 1.1 9.6 0.8 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAJ22033.1 - 0.00052 20.0 0.1 3.7 7.5 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 OAJ22033.1 - 0.00082 18.6 0.0 0.77 8.8 0.0 2.5 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 OAJ22033.1 - 0.0023 18.5 0.0 3.8 8.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAJ22033.1 - 0.0038 17.2 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain PRK PF00485.18 OAJ22033.1 - 0.0045 16.8 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 OAJ22033.1 - 0.0087 16.2 3.1 2.5 8.2 0.0 3.7 4 0 0 4 4 4 1 Helicase HerA, central domain RNA_helicase PF00910.22 OAJ22033.1 - 0.014 15.8 0.0 6.9 7.1 0.0 3.7 4 0 0 4 4 3 0 RNA helicase NB-ARC PF00931.22 OAJ22033.1 - 0.02 14.1 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 OAJ22033.1 - 0.024 14.2 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 OAJ22033.1 - 0.024 14.9 3.3 9 6.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 OAJ22033.1 - 0.037 13.8 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 OAJ22033.1 - 0.04 13.8 0.1 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 OAJ22033.1 - 0.065 13.4 2.8 2.7 8.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 OAJ22033.1 - 0.091 12.4 0.1 8.6 5.9 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 OAJ22033.1 - 0.13 12.7 0.0 26 5.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 OAJ22033.1 - 0.15 12.2 0.2 16 5.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 OAJ22033.1 - 0.17 11.8 0.3 27 4.6 0.1 2.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 OAJ22033.1 - 0.28 10.9 3.2 5.7 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain IER PF05760.12 OAJ22033.1 - 0.3 11.3 11.1 0.69 10.2 11.1 1.5 1 0 0 1 1 1 0 Immediate early response protein (IER) Macoilin PF09726.9 OAJ22033.1 - 1.1 7.8 5.2 1.9 6.9 5.2 1.4 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 OAJ22033.1 - 1.4 8.8 25.9 3.2 7.6 25.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.31 OAJ22034.1 - 5.2e-16 59.0 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAJ22034.1 - 5.2e-13 49.2 0.7 1.6e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OAJ22034.1 - 1.5e-08 34.6 0.0 3.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ22034.1 - 6.6e-06 26.4 0.1 1.8e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 OAJ22034.1 - 0.0007 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.15 OAJ22034.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 OAJ22034.1 - 0.048 13.0 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAJ22034.1 - 0.049 14.0 2.9 0.093 13.1 0.3 2.8 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_S8 PF00082.22 OAJ22035.1 - 8.3e-58 196.0 2.8 1.3e-57 195.4 2.8 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 OAJ22035.1 - 5.9e-40 136.8 0.0 9e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II ETF PF01012.21 OAJ22036.1 - 8e-42 143.2 3.0 1.2e-41 142.6 3.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain BOP1NT PF08145.12 OAJ22037.1 - 4.5e-106 354.5 1.5 6.3e-106 354.0 1.5 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAJ22037.1 - 5.4e-21 74.5 0.0 3.6e-06 27.6 0.0 6.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ22037.1 - 0.00032 20.9 0.0 2.5 8.5 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2457 PF10446.9 OAJ22037.1 - 0.061 12.5 21.3 0.12 11.5 21.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TEX19 PF15553.6 OAJ22037.1 - 1.7 8.6 5.6 28 4.7 0.0 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 BUD22 PF09073.10 OAJ22037.1 - 4.3 6.6 19.0 6.9 5.9 19.0 1.3 1 0 0 1 1 1 0 BUD22 Actin PF00022.19 OAJ22038.1 - 2.2e-108 362.5 0.0 3.2e-108 362.0 0.0 1.2 1 0 0 1 1 1 1 Actin Maf1 PF09174.10 OAJ22039.1 - 8.7e-29 100.9 3.1 3.6e-18 66.3 0.0 3.7 4 0 0 4 4 4 3 Maf1 regulator SDA1 PF05285.12 OAJ22040.1 - 6.1e-05 22.6 11.6 6.1e-05 22.6 11.6 5.1 4 1 0 4 4 4 2 SDA1 Sad1_UNC PF07738.13 OAJ22041.1 - 9.4e-12 45.1 0.0 1.1e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF4632 PF15451.6 OAJ22041.1 - 0.062 13.4 1.1 0.32 11.1 1.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Glyco_hydro_16 PF00722.21 OAJ22042.1 - 3.1e-15 56.1 0.1 5e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Peptidase_S48 PF03574.15 OAJ22042.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S48 FGGY_C PF02782.16 OAJ22045.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain IMS PF00817.20 OAJ22046.1 - 2.9e-38 131.2 0.0 5.5e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ22046.1 - 5e-10 40.1 0.0 1.8e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 OAJ22046.1 - 3.3e-09 37.0 2.6 6.5e-09 36.1 2.6 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain DUF1805 PF08827.11 OAJ22046.1 - 0.12 12.7 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) UBM PF14377.6 OAJ22046.1 - 0.44 10.1 4.2 8.2 6.0 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin binding region Ribosomal_L37 PF08561.10 OAJ22047.1 - 6.7e-28 97.6 4.0 4.3e-27 95.0 4.0 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 Pkinase PF00069.25 OAJ22050.1 - 3e-18 66.1 0.0 2.4e-15 56.6 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22050.1 - 6.8e-05 22.3 0.1 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAJ22050.1 - 0.0056 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_tranf_2_3 PF13641.6 OAJ22051.1 - 8.2e-13 48.8 0.4 4.5e-10 39.8 0.4 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 OAJ22051.1 - 4.1e-11 42.2 9.5 2.3e-09 36.4 8.4 3.3 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.6 OAJ22051.1 - 4.4e-11 42.6 0.1 8.5e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OAJ22051.1 - 3.8e-10 40.0 6.4 3.8e-10 40.0 6.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAJ22051.1 - 0.01 15.7 0.1 0.27 11.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2703 PF10865.8 OAJ22052.1 - 0.098 12.8 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) AAA_11 PF13086.6 OAJ22053.1 - 3.5e-55 187.6 0.0 3.5e-55 187.6 0.0 4.5 4 1 0 4 4 4 1 AAA domain AAA_12 PF13087.6 OAJ22053.1 - 9e-50 169.1 0.0 2.1e-49 167.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ22053.1 - 5.5e-09 36.0 0.6 3.8e-05 23.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 OAJ22053.1 - 7e-06 26.4 0.0 0.00059 20.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ22053.1 - 0.00014 21.5 0.0 0.027 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAJ22053.1 - 0.00026 20.8 0.0 0.6 9.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAJ22053.1 - 0.00059 19.5 0.1 0.9 9.0 0.0 2.6 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 OAJ22053.1 - 0.0013 18.5 0.4 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 OAJ22053.1 - 0.0033 17.7 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ22053.1 - 0.0068 16.8 0.6 0.032 14.7 0.3 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ22053.1 - 0.011 16.1 0.0 0.046 14.1 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 OAJ22053.1 - 0.094 13.2 18.1 0.27 11.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain Mak10 PF04112.13 OAJ22054.1 - 2.1e-47 160.8 0.0 4e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Chitin_synth_1 PF01644.17 OAJ22057.1 - 7.8e-80 266.6 0.0 1.1e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ22057.1 - 5.6e-29 99.9 0.1 1.1e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ22057.1 - 1.2e-23 83.5 8.7 1.9e-22 79.6 0.2 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ22057.1 - 2e-07 31.2 0.5 2e-07 31.2 0.5 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 DUF1195 PF06708.11 OAJ22057.1 - 0.039 13.7 0.2 0.096 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Ion_trans_2 PF07885.16 OAJ22058.1 - 1.2e-31 108.5 31.2 8.4e-16 57.7 9.8 2.7 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 OAJ22058.1 - 9.2e-05 21.8 16.1 0.0054 16.0 3.8 2.5 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 OAJ22058.1 - 0.015 15.2 7.6 0.16 11.8 0.4 2.6 2 1 0 2 2 2 0 Ligand-gated ion channel DUF4834 PF16118.5 OAJ22058.1 - 1.9 9.5 0.0 1.9 9.5 0.0 5.4 5 1 0 5 5 5 0 Domain of unknown function (DUF4834) CoA_binding_3 PF13727.6 OAJ22058.1 - 2.6 8.0 6.5 0.57 10.2 0.4 2.4 2 0 0 2 2 2 0 CoA-binding domain Pkinase PF00069.25 OAJ22059.1 - 7.4e-38 130.4 0.0 4e-26 92.0 0.0 4.5 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22059.1 - 1.7e-21 76.7 0.0 2.8e-18 66.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ22059.1 - 0.00078 19.4 0.1 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ22059.1 - 0.046 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 OAJ22059.1 - 0.14 11.4 0.1 4.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Dynamin_N PF00350.23 OAJ22060.1 - 7.7e-17 61.9 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAJ22060.1 - 1.4e-11 44.4 0.0 5e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ22060.1 - 1.2e-08 34.7 0.1 1.1e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ22060.1 - 0.00024 21.0 0.9 0.42 10.5 0.2 2.8 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 OAJ22060.1 - 0.00089 18.9 0.2 0.13 11.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 OAJ22060.1 - 0.0013 17.9 0.3 0.045 12.8 0.0 2.8 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 OAJ22060.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAJ22060.1 - 0.024 14.8 0.2 1.4 9.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ22060.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ22060.1 - 0.059 13.8 2.0 0.4 11.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 OAJ22060.1 - 0.14 11.6 0.9 7.7 5.9 0.0 2.9 2 1 1 3 3 3 0 ADP-ribosylation factor family Ribosomal_L30 PF00327.20 OAJ22061.1 - 1.5e-09 37.5 0.1 2.2e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SWIM PF04434.17 OAJ22062.1 - 5.9e-05 22.6 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger Aconitase_B_N PF11791.8 OAJ22062.1 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain COX16 PF14138.6 OAJ22062.1 - 0.12 12.9 0.1 4.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Isy1 PF06246.12 OAJ22064.1 - 6.2e-81 271.7 8.6 2.6e-78 263.1 3.8 2.0 1 1 1 2 2 2 2 Isy1-like splicing family Torus PF16131.5 OAJ22065.1 - 1.4e-05 25.8 1.7 0.00051 20.7 0.0 2.7 2 0 0 2 2 2 1 Torus domain zf-C3HC4 PF00097.25 OAJ22065.1 - 1.8e-05 24.5 3.4 4.9e-05 23.1 0.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ22065.1 - 0.00029 20.8 0.6 0.00076 19.4 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ22065.1 - 0.00039 20.7 0.9 0.00039 20.7 0.9 3.3 3 1 0 3 3 3 1 Ring finger domain zf-CCCH_4 PF18044.1 OAJ22065.1 - 0.00043 20.0 13.1 0.042 13.7 0.7 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ22065.1 - 0.00099 19.1 6.1 0.00099 19.1 6.1 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-C3HC4_2 PF13923.6 OAJ22065.1 - 0.0018 18.1 0.8 0.0018 18.1 0.8 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 OAJ22065.1 - 0.0053 17.2 13.3 0.59 10.7 0.5 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3HC4_3 PF13920.6 OAJ22065.1 - 0.026 14.4 0.7 0.026 14.4 0.7 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 OAJ22065.1 - 0.026 14.4 0.7 0.026 14.4 0.7 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 PF12678.7 OAJ22065.1 - 0.076 13.3 2.9 0.68 10.3 0.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 OAJ22065.1 - 0.095 12.7 3.3 0.32 11.0 1.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ22065.1 - 0.54 10.2 4.7 7 6.6 1.3 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ22065.1 - 0.62 10.3 5.6 0.12 12.5 1.5 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TMF_DNA_bd PF12329.8 OAJ22066.1 - 3.8e-06 26.8 9.7 5.7e-06 26.2 9.7 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Angiomotin_C PF12240.8 OAJ22066.1 - 2.5e-05 24.0 7.5 0.00013 21.6 7.5 1.8 1 1 0 1 1 1 1 Angiomotin C terminal Jnk-SapK_ap_N PF09744.9 OAJ22066.1 - 0.0002 21.6 7.1 0.0003 21.1 7.1 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Atg14 PF10186.9 OAJ22066.1 - 0.00057 19.1 6.6 0.00066 18.9 6.6 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 OAJ22066.1 - 0.00086 19.2 8.8 0.00094 19.1 8.8 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family ATG16 PF08614.11 OAJ22066.1 - 0.0014 18.8 10.7 0.0018 18.5 10.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IFT57 PF10498.9 OAJ22066.1 - 0.0022 17.1 4.4 0.0026 16.8 4.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fmp27_WPPW PF10359.9 OAJ22066.1 - 0.0024 16.8 2.6 0.0027 16.6 2.6 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain PKcGMP_CC PF16808.5 OAJ22066.1 - 0.0027 17.5 3.7 0.0027 17.5 3.7 2.8 3 1 0 3 3 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_CTD PF16326.5 OAJ22066.1 - 0.0031 17.7 8.1 0.0031 17.7 8.1 2.1 1 1 1 2 2 2 1 ABC transporter C-terminal domain DUF3450 PF11932.8 OAJ22066.1 - 0.005 16.2 4.2 0.0059 15.9 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ADIP PF11559.8 OAJ22066.1 - 0.0078 16.3 7.0 0.0095 16.0 7.0 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 OAJ22066.1 - 0.0092 16.1 8.9 0.012 15.7 8.9 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF641 PF04859.12 OAJ22066.1 - 0.011 16.1 4.6 0.014 15.8 4.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 OAJ22066.1 - 0.012 14.5 8.3 0.015 14.2 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.6 OAJ22066.1 - 0.014 15.1 7.9 0.017 14.8 7.9 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 OAJ22066.1 - 0.019 15.5 0.5 0.024 15.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 OAJ22066.1 - 0.022 14.7 4.0 0.022 14.7 4.0 2.0 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 OAJ22066.1 - 0.024 14.0 2.9 0.033 13.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 OAJ22066.1 - 0.033 12.8 5.0 0.036 12.7 5.0 1.0 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 OAJ22066.1 - 0.039 14.5 11.1 0.051 14.1 11.1 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Phlebovirus_NSM PF07246.11 OAJ22066.1 - 0.042 13.2 2.9 0.05 13.0 2.9 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF724 PF05266.14 OAJ22066.1 - 0.065 13.1 4.7 0.084 12.7 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 OAJ22066.1 - 0.08 12.3 1.1 0.093 12.1 1.1 1.1 1 0 0 1 1 1 0 FAM76 protein VPS38 PF17649.1 OAJ22066.1 - 0.093 11.6 0.7 0.11 11.3 0.7 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 V_ATPase_I PF01496.19 OAJ22066.1 - 0.094 10.6 1.2 0.1 10.5 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 OAJ22066.1 - 0.1 12.6 9.1 0.14 12.1 9.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRI3BP PF14965.6 OAJ22066.1 - 0.11 12.0 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Baculo_PEP_C PF04513.12 OAJ22066.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 OAJ22066.1 - 0.13 12.7 7.3 0.16 12.4 6.9 1.3 1 1 0 1 1 1 0 Fez1 4HB_MCP_1 PF12729.7 OAJ22066.1 - 0.14 11.7 3.7 0.18 11.3 3.7 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Med4 PF10018.9 OAJ22066.1 - 0.14 11.8 6.5 0.094 12.4 1.2 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sigma_1_2 PF03084.14 OAJ22066.1 - 0.16 11.2 0.1 0.19 11.0 0.1 1.0 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family PRKG1_interact PF15898.5 OAJ22066.1 - 0.31 12.0 8.8 1.2 10.1 9.0 1.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain PEARLI-4 PF05278.12 OAJ22066.1 - 0.32 10.6 6.7 0.39 10.3 6.7 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) SlyX PF04102.12 OAJ22066.1 - 0.36 11.5 8.1 0.082 13.5 2.1 2.2 1 1 1 2 2 2 0 SlyX TMPIT PF07851.13 OAJ22066.1 - 0.38 9.9 2.0 0.44 9.7 2.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.6 OAJ22066.1 - 0.85 9.8 9.4 1.2 9.4 9.4 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DivIC PF04977.15 OAJ22066.1 - 1.5 8.6 9.4 7 6.5 9.4 2.1 1 1 0 1 1 1 0 Septum formation initiator CorA PF01544.18 OAJ22066.1 - 2.9 7.1 4.8 3.4 6.9 4.8 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein OmpH PF03938.14 OAJ22066.1 - 3.6 7.9 9.5 8.5 6.7 9.6 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4315 PF14193.6 OAJ22066.1 - 5.7 7.0 13.5 0.081 12.9 4.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Peptidase_S8 PF00082.22 OAJ22085.1 - 8.2e-43 146.8 3.1 1.3e-42 146.1 3.1 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ22085.1 - 4.3e-15 56.4 0.1 9.2e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAJ22085.1 - 2.8e-05 24.1 0.0 7.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 PA domain TRAP_beta PF05753.14 OAJ22085.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) UQ_con PF00179.26 OAJ22086.1 - 2.1e-46 157.1 0.0 2.3e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ22086.1 - 0.00022 20.9 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAJ22086.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAJ22086.1 - 0.091 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Actin PF00022.19 OAJ22087.1 - 3e-127 424.6 0.0 1.5e-126 422.3 0.0 1.8 1 1 0 1 1 1 1 Actin Sec63 PF02889.16 OAJ22088.1 - 6.8e-152 503.9 0.0 1.3e-83 280.1 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAJ22088.1 - 3.5e-42 144.1 0.0 2.2e-24 86.2 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAJ22088.1 - 1e-36 125.4 0.1 3.1e-36 123.9 0.1 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 OAJ22088.1 - 1.6e-19 70.5 0.0 3.3e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ22088.1 - 8.5e-12 45.4 0.0 1.3e-07 32.0 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ22088.1 - 4.1e-06 26.7 0.1 0.0072 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ22088.1 - 0.00018 21.8 0.1 0.09 13.1 0.1 3.4 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 OAJ22088.1 - 0.071 12.5 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PHD PF00628.29 OAJ22089.1 - 8.4e-07 28.8 14.0 1.5e-06 28.0 14.0 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 OAJ22089.1 - 0.016 15.6 0.0 0.016 15.6 0.0 4.4 3 2 0 3 3 3 0 SET domain PHD_2 PF13831.6 OAJ22089.1 - 0.12 12.0 4.6 0.21 11.2 4.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 OAJ22089.1 - 0.38 10.8 3.7 0.75 9.9 3.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Cnd1 PF12717.7 OAJ22090.1 - 1.1e-05 25.5 0.3 0.0025 17.9 0.0 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ22090.1 - 0.00037 20.8 0.4 0.035 14.5 0.1 4.8 3 1 3 6 6 6 2 HEAT repeats HEAT PF02985.22 OAJ22090.1 - 0.0015 18.6 7.0 0.73 10.3 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat UQ_con PF00179.26 OAJ22091.1 - 3.2e-22 78.7 0.0 6.3e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 OAJ22091.1 - 0.005 17.0 4.7 0.015 15.5 4.7 1.8 1 1 0 1 1 1 1 IBR domain, a half RING-finger domain Cid2 PF09774.9 OAJ22091.1 - 3.6 8.0 8.0 0.95 9.9 4.0 2.1 2 0 0 2 2 2 0 Caffeine-induced death protein 2 WD40 PF00400.32 OAJ22092.1 - 2.7e-09 37.5 10.3 0.019 15.8 1.0 5.5 4 1 1 5 5 5 3 WD domain, G-beta repeat Mis14 PF08641.12 OAJ22093.1 - 2.6e-10 40.7 7.1 4.1e-10 40.1 7.1 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Syntaxin-6_N PF09177.11 OAJ22093.1 - 0.11 13.1 5.2 0.13 12.8 1.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4570 PF15134.6 OAJ22093.1 - 0.13 12.3 7.9 0.04 13.9 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF2937 PF11157.8 OAJ22093.1 - 0.19 11.4 3.2 0.35 10.6 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF349 PF03993.12 OAJ22093.1 - 2.4 8.5 8.4 9.9 6.5 8.1 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Spc24 PF08286.11 OAJ22093.1 - 5.9 7.2 8.2 1.7e+02 2.5 7.4 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 RNA_pol_Rpb2_1 PF04563.15 OAJ22094.1 - 3.1e-61 206.4 0.2 4.3e-61 206.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ22094.1 - 2.1e-34 118.8 0.2 6.5e-34 117.2 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 OAJ22094.1 - 1.9e-25 88.9 0.3 4.4e-25 87.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAJ22094.1 - 1.1e-20 73.5 0.0 2.7e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAJ22094.1 - 4.3e-09 36.8 2.2 4.3e-09 36.8 2.2 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Aldo_ket_red PF00248.21 OAJ22094.1 - 0.025 13.8 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family RNA_pol_Rpb2_6 PF00562.28 OAJ22094.1 - 0.15 11.1 0.4 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 6 Histone_H2A_C PF16211.5 OAJ22095.1 - 1.7e-18 66.1 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ22095.1 - 1.2e-16 61.2 0.0 1.8e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ22095.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ22096.1 - 1.5e-22 80.4 0.1 1.9e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ22096.1 - 4.8e-07 30.0 0.1 9.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAJ22096.1 - 0.00045 20.7 0.0 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 OAJ22096.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein RP-C PF03428.13 OAJ22096.1 - 0.098 12.3 0.2 0.3 10.7 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Ribosomal_L24e PF01246.20 OAJ22097.1 - 6.1e-31 106.5 0.6 6.1e-31 106.5 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e GlcNAc PF11397.8 OAJ22097.1 - 0.088 12.2 2.4 0.12 11.8 2.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) GLTP PF08718.11 OAJ22098.1 - 4.6e-49 166.5 0.0 1e-48 165.4 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PTS_2-RNA PF01885.16 OAJ22099.1 - 1.1e-52 178.7 0.0 4.1e-52 176.9 0.0 1.7 2 0 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CLTH PF10607.9 OAJ22100.1 - 1e-26 93.6 0.0 1.5e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAJ22100.1 - 7.8e-11 41.5 0.5 1.5e-10 40.6 0.1 1.7 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.19 OAJ22100.1 - 0.00011 22.7 3.9 0.00011 22.7 3.9 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein DWNN PF08783.11 OAJ22101.1 - 8.2e-32 109.3 0.0 1.4e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAJ22101.1 - 1.7e-09 37.3 7.0 3e-09 36.5 7.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ22101.1 - 4.7e-06 26.4 1.7 9.6e-06 25.4 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ22101.1 - 0.0033 17.4 0.1 0.0093 15.9 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 OAJ22101.1 - 0.0065 16.3 9.4 0.0065 16.3 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 OAJ22101.1 - 0.032 13.9 0.5 0.09 12.5 0.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_2 PF13639.6 OAJ22101.1 - 0.55 10.6 11.2 1.2 9.6 11.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ22101.1 - 0.67 10.2 12.4 1.5 9.0 12.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAJ22101.1 - 1.6 8.7 19.7 0.039 13.8 12.9 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ22101.1 - 2.6 8.2 9.4 5.2 7.2 9.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ22101.1 - 2.7 7.9 13.5 5 7.1 13.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) gp12-short_mid PF09089.10 OAJ22102.1 - 0.044 13.9 0.3 0.044 13.9 0.3 3.1 2 1 1 3 3 3 0 Phage short tail fibre protein gp12, middle domain CN_hydrolase PF00795.22 OAJ22104.1 - 1.1e-10 41.3 0.0 8.9e-08 31.8 0.0 3.1 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase Oxysterol_BP PF01237.18 OAJ22105.1 - 2.8e-45 154.8 11.1 2e-28 99.3 0.2 4.1 2 1 1 3 3 3 2 Oxysterol-binding protein FYDLN_acid PF09538.10 OAJ22105.1 - 10 6.9 10.1 0.34 11.6 1.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) NUDIX PF00293.28 OAJ22106.1 - 6.5e-13 48.9 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAJ22106.1 - 1.6e-10 41.5 2.7 8.4e-10 39.2 2.7 2.3 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-C2H2 PF00096.26 OAJ22107.1 - 4.2e-10 39.5 10.3 4.1e-05 23.8 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ22107.1 - 6.7e-05 23.1 2.1 6.7e-05 23.1 2.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ22107.1 - 0.00031 21.3 9.0 0.16 12.8 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ22107.1 - 0.0076 16.9 3.0 1.5 9.5 0.1 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain NOA36 PF06524.12 OAJ22107.1 - 0.087 12.1 0.6 0.14 11.5 0.6 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_12 PF13424.6 OAJ22108.1 - 1.2e-05 25.5 10.2 0.0096 16.2 0.2 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ22108.1 - 0.00028 20.7 0.1 2 8.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ22108.1 - 0.0017 18.3 13.3 0.096 12.9 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ22108.1 - 0.015 15.1 5.1 2.8 7.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 OAJ22108.1 - 0.75 9.9 3.3 2 8.6 0.3 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pyr_redox_2 PF07992.14 OAJ22109.1 - 4.3e-67 226.4 0.2 6.1e-67 225.9 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ22109.1 - 9.9e-35 119.1 0.9 2.2e-34 118.0 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ22109.1 - 2.9e-20 72.6 5.7 2.9e-18 66.2 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ22109.1 - 1.7e-13 50.5 0.1 2.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ22109.1 - 9.9e-07 27.8 0.8 0.036 12.8 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 OAJ22109.1 - 1.7e-05 24.1 0.1 0.00012 21.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OAJ22109.1 - 0.00039 19.9 0.4 0.00079 18.9 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ22109.1 - 0.013 15.8 1.2 0.041 14.1 1.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 OAJ22109.1 - 0.016 15.2 0.0 7.2 6.6 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 OAJ22109.1 - 0.037 13.9 3.2 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAJ22109.1 - 0.074 12.1 2.6 0.89 8.6 2.1 2.3 2 0 0 2 2 2 0 FAD binding domain XdhC_C PF13478.6 OAJ22109.1 - 0.13 12.8 0.0 30 5.1 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 OAJ22109.1 - 0.18 12.3 0.1 14 6.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding ERM PF00769.19 OAJ22110.1 - 8.3e-05 22.5 20.8 8.3e-05 22.5 20.8 2.4 2 0 0 2 2 2 1 Ezrin/radixin/moesin family SDA1 PF05285.12 OAJ22110.1 - 0.0011 18.5 34.2 0.0011 18.5 34.2 2.8 3 0 0 3 3 3 1 SDA1 DUF1664 PF07889.12 OAJ22110.1 - 0.018 15.1 1.3 0.018 15.1 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 OAJ22110.1 - 1.1 8.6 21.7 0.7 9.2 11.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 OAJ22110.1 - 3.9 7.7 8.5 6.7 6.9 7.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Myc_N PF01056.18 OAJ22111.1 - 0.35 10.7 16.0 0.07 13.0 2.0 3.3 3 0 0 3 3 3 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 OAJ22111.1 - 2.2 8.7 13.6 3.8 7.9 1.9 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Lipase_3 PF01764.25 OAJ22112.1 - 1.2e-14 54.4 0.0 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ22112.1 - 0.0013 19.4 1.8 0.041 14.5 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ22112.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ22112.1 - 0.033 13.4 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CDC45 PF02724.14 OAJ22112.1 - 3.1 6.0 5.1 4.1 5.6 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3395 PF11875.8 OAJ22113.1 - 2.5e-39 134.7 0.0 4.3e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 OAJ22113.1 - 3.6e-20 71.9 0.8 3.6e-20 71.9 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain NTP_transf_2 PF01909.23 OAJ22114.1 - 4.9e-07 30.0 0.0 9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ22114.1 - 0.029 14.5 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase WH1 PF00568.23 OAJ22117.1 - 1e-13 51.2 0.0 3.1e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 WH1 domain PBD PF00786.28 OAJ22117.1 - 3.8e-09 36.8 0.0 6.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 OAJ22117.1 - 8.5e-06 25.4 0.2 2.2e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 WH2 motif Trypan_PARP PF05887.11 OAJ22118.1 - 0.02 14.8 4.4 0.029 14.3 4.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.13 OAJ22118.1 - 3.1 8.5 9.4 4.5 7.9 9.4 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lactamase_B_2 PF12706.7 OAJ22121.1 - 8.4e-12 45.0 0.0 1.7e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ22121.1 - 3.6e-09 36.2 0.0 1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ22121.1 - 0.045 13.7 0.1 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Ada3 PF10198.9 OAJ22123.1 - 5.6e-26 91.3 0.0 4.1e-25 88.4 0.0 2.2 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Pmp3 PF01679.17 OAJ22124.1 - 1.4e-17 63.6 9.2 2.1e-17 63.0 9.2 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TruD PF01142.18 OAJ22125.1 - 2.8e-53 181.3 0.0 5e-42 144.2 0.0 5.0 4 1 1 5 5 5 4 tRNA pseudouridine synthase D (TruD) RRM_1 PF00076.22 OAJ22126.1 - 9.2e-13 47.8 0.0 1.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAJ22126.1 - 9.2e-08 32.5 1.0 9.2e-08 32.5 1.0 3.1 3 0 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 CENP-U PF13097.6 OAJ22126.1 - 0.0096 15.9 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit RRM_occluded PF16842.5 OAJ22126.1 - 0.021 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amidohydro_1 PF01979.20 OAJ22127.1 - 1.7e-57 195.3 0.0 2.1e-54 185.1 0.0 2.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 OAJ22127.1 - 8.7e-08 32.1 0.1 0.011 15.3 0.1 3.1 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAJ22127.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 OAJ22128.1 - 9.4e-67 225.1 0.0 1.3e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22128.1 - 3.8e-52 177.1 0.0 6e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 OAJ22128.1 - 6.8e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain C1_1 PF00130.22 OAJ22128.1 - 0.00018 21.3 10.2 0.0003 20.6 10.2 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 OAJ22128.1 - 0.0027 17.3 7.5 0.0056 16.3 7.5 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Kinase-like PF14531.6 OAJ22128.1 - 0.0047 16.3 0.1 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like CDC24 PF06395.11 OAJ22128.1 - 0.03 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 CDC24 Calponin RIO1 PF01163.22 OAJ22128.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 OAJ22128.1 - 0.17 10.9 0.1 0.27 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zinc_ribbon_2 PF13240.6 OAJ22128.1 - 0.37 10.6 2.5 0.71 9.7 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PHD PF00628.29 OAJ22128.1 - 1.6 8.7 10.2 3 7.8 10.2 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_C97 PF05903.14 OAJ22129.1 - 1.4e-16 60.6 0.0 2.8e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain DUF4796 PF16044.5 OAJ22129.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Gar1 PF04410.14 OAJ22130.1 - 5.3e-28 97.7 0.7 1e-15 57.9 0.0 3.4 3 0 0 3 3 3 3 Gar1/Naf1 RNA binding region EXOSC1 PF10447.9 OAJ22131.1 - 1.6e-25 89.8 0.1 3.3e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 BetaGal_dom4_5 PF13364.6 OAJ22149.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain ComZ PF10815.8 OAJ22149.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 ComZ VWA_2 PF13519.6 OAJ22150.1 - 4e-05 24.2 0.0 8.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ22150.1 - 0.0002 21.6 0.0 0.00047 20.4 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Usp PF00582.26 OAJ22151.1 - 2e-13 51.1 2.8 3.8e-13 50.1 0.7 2.4 2 1 0 2 2 2 1 Universal stress protein family Gram_pos_anchor PF00746.21 OAJ22152.1 - 8.8 6.4 6.7 5.4 7.1 4.3 2.0 1 1 1 2 2 2 0 LPXTG cell wall anchor motif Pkinase PF00069.25 OAJ22153.1 - 2.5e-71 240.1 0.0 3.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22153.1 - 4.8e-30 104.7 0.0 1.9e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22153.1 - 6.1e-07 29.0 2.6 0.0015 17.9 0.2 3.0 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 OAJ22153.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ22153.1 - 0.073 11.8 0.0 0.073 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase ARID PF01388.21 OAJ22154.1 - 4.3e-17 62.6 0.0 4.3e-17 62.6 0.0 3.8 2 1 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 OAJ22154.1 - 1.2e-16 61.0 5.8 1.2e-16 61.0 5.8 7.3 7 1 1 8 8 8 1 Mediator complex subunit 15 CDK2AP PF09806.9 OAJ22154.1 - 0.0022 18.1 4.3 0.0022 18.1 4.3 9.1 4 3 3 7 7 7 1 Cyclin-dependent kinase 2-associated protein WD40 PF00400.32 OAJ22155.1 - 1.5e-13 50.9 15.2 0.0013 19.5 0.2 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ22155.1 - 1e-08 35.3 0.1 0.0015 18.8 0.0 3.7 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 OAJ22155.1 - 0.0026 16.6 0.3 0.082 11.6 0.5 2.4 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PRKCSH-like PF12999.7 OAJ22158.1 - 8.6e-43 146.1 5.2 8.6e-43 146.1 5.2 2.3 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 OAJ22158.1 - 4.1e-28 98.0 0.1 9e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAJ22158.1 - 1.4e-09 38.8 2.3 2.8e-09 37.8 2.3 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Effector_1 PF04518.12 OAJ22158.1 - 0.0018 17.4 0.5 0.0018 17.4 0.5 1.4 2 0 0 2 2 2 1 Effector from type III secretion system DUF3584 PF12128.8 OAJ22158.1 - 0.0021 15.7 1.8 0.0021 15.7 1.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 OAJ22158.1 - 0.0084 15.0 0.2 0.013 14.4 0.2 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2968 PF11180.8 OAJ22158.1 - 0.01 15.5 5.1 0.035 13.8 3.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.21 OAJ22158.1 - 0.043 13.9 5.2 1.9 8.6 0.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.18 OAJ22158.1 - 0.043 14.0 3.2 0.097 12.9 3.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper YscO PF07321.12 OAJ22158.1 - 0.061 13.3 10.1 0.029 14.3 6.2 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Mt_ATP-synt_B PF05405.14 OAJ22158.1 - 0.57 9.8 3.5 0.25 10.9 1.0 1.7 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Halogen_Hydrol PF10112.9 OAJ22158.1 - 0.89 9.5 5.8 11 6.0 0.2 3.1 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YabA PF06156.13 OAJ22158.1 - 1.2 9.8 3.5 19 5.9 0.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 OAJ22158.1 - 4.6 7.6 9.8 63 3.9 5.7 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF4407 PF14362.6 OAJ22158.1 - 5.3 6.3 8.0 1.6 8.0 3.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 OAJ22159.1 - 1.1e-44 152.7 0.0 1.1e-31 110.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22159.1 - 3.2e-20 72.5 0.0 2.3e-19 69.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ22159.1 - 0.00028 20.9 1.2 0.0003 20.8 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ22159.1 - 0.0006 19.2 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ22159.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ22159.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ22159.1 - 0.047 12.5 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Diphthami_syn_2 PF01902.17 OAJ22160.1 - 1.2e-36 126.3 0.0 9.7e-35 120.0 0.0 2.3 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAJ22160.1 - 5.8e-21 74.7 0.0 2.7e-13 50.0 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 OAJ22160.1 - 0.0091 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase LSM PF01423.22 OAJ22161.1 - 2.4e-18 65.6 0.4 3.5e-18 65.1 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ22161.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Hfq protein DEAD PF00270.29 OAJ22163.1 - 5.2e-41 140.3 0.0 9.8e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22163.1 - 2.6e-24 85.7 0.0 7.6e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ22163.1 - 0.029 14.4 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MtlR PF05068.12 OAJ22163.1 - 0.11 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Mannitol repressor MFS_1 PF07690.16 OAJ22165.1 - 4e-20 72.1 38.3 2.9e-13 49.5 22.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAJ22165.1 - 6.5e-11 42.2 15.0 8e-11 41.9 6.0 2.3 2 0 0 2 2 2 2 Nodulin-like zf-CCHH PF10283.9 OAJ22165.1 - 0.064 13.3 1.5 0.12 12.4 1.5 1.4 1 0 0 1 1 1 0 PBZ domain Lustrin_cystein PF14625.6 OAJ22165.1 - 1.4 9.4 3.2 2.7 8.5 3.2 1.4 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain GMC_oxred_N PF00732.19 OAJ22166.1 - 8.7e-49 166.5 0.1 1.6e-48 165.6 0.1 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ22166.1 - 4.8e-32 111.5 0.0 8.6e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ22166.1 - 4.9e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ22166.1 - 6e-06 25.6 0.0 0.00046 19.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ22166.1 - 7.5e-05 21.9 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 OAJ22166.1 - 0.0047 16.6 2.0 0.0048 16.5 0.1 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ22166.1 - 0.0066 15.7 0.1 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ22166.1 - 0.027 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAJ22166.1 - 0.027 13.7 0.0 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ22166.1 - 0.03 14.6 0.1 0.067 13.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 OAJ22166.1 - 0.066 13.2 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 OAJ22166.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAJ22166.1 - 0.12 11.6 0.1 0.24 10.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family GCP_N_terminal PF17681.1 OAJ22167.1 - 4.6e-88 295.8 0.0 8.4e-87 291.6 0.0 2.7 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ22167.1 - 1.3e-77 261.4 0.9 3.9e-77 259.8 0.3 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF1748 PF08520.10 OAJ22168.1 - 1.7e-26 91.9 0.0 1.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Ras PF00071.22 OAJ22169.1 - 1.6e-47 161.1 0.0 2.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ22169.1 - 1.8e-17 63.7 0.0 2.6e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ22169.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ22169.1 - 8.3e-05 22.6 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ22169.1 - 0.0013 18.8 0.1 0.0025 17.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ22169.1 - 0.0018 17.8 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 OAJ22169.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OAJ22169.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 AIG1 family DnaJ_C PF01556.18 OAJ22170.1 - 1.2e-28 100.0 0.1 1.8e-28 99.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ22170.1 - 8e-21 73.9 5.5 1.4e-20 73.1 5.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ22170.1 - 1.2e-14 54.4 16.9 2e-14 53.7 16.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAJ22170.1 - 0.0019 18.1 6.8 0.19 11.7 0.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAJ22170.1 - 0.0048 16.9 7.9 0.52 10.3 2.8 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 OAJ22170.1 - 1.6 8.3 7.8 0.55 9.9 0.6 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 OAJ22170.1 - 1.9 8.7 7.7 0.34 11.1 0.8 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 OAJ22170.1 - 7.2 6.7 9.5 17 5.5 9.5 1.7 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 OAJ22170.1 - 8.7 6.8 6.8 5.5 7.4 3.8 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Acyl_transf_3 PF01757.22 OAJ22172.1 - 0.0012 18.0 34.2 0.0015 17.7 34.2 1.1 1 0 0 1 1 1 1 Acyltransferase family Apt1 PF10351.9 OAJ22173.1 - 1.2e-118 397.0 0.9 1.2e-118 397.0 0.9 3.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 OAJ22173.1 - 9.7e-61 206.1 0.0 3.7e-60 204.2 0.0 1.9 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 OAJ22173.1 - 7.2e-44 149.6 0.0 1.6e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAJ22173.1 - 1e-39 136.0 0.1 2.3e-39 134.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 OAJ22173.1 - 3.8e-24 85.4 0.0 9.5e-23 80.9 0.0 3.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apis_Csd PF11671.8 OAJ22173.1 - 0.51 10.3 4.8 1.5 8.9 4.8 1.8 1 0 0 1 1 1 0 Complementary sex determiner protein Acyl_transf_3 PF01757.22 OAJ22174.1 - 5.5e-15 55.3 44.8 1.8e-14 53.6 44.8 1.9 1 1 0 1 1 1 1 Acyltransferase family Presenilin PF01080.17 OAJ22174.1 - 0.13 11.0 1.5 0.29 9.9 1.5 1.5 1 0 0 1 1 1 0 Presenilin Abhydrolase_3 PF07859.13 OAJ22175.1 - 1.1e-21 77.7 0.6 1.4e-21 77.3 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 OAJ22175.1 - 0.024 14.2 0.0 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 OAJ22175.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PH_14 PF17787.1 OAJ22176.1 - 1.4 8.8 6.4 46 3.9 0.0 4.6 3 1 3 6 6 6 0 PH domain Glycoprotein_G PF00802.19 OAJ22176.1 - 2 7.7 21.2 3.8 6.8 21.2 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G MerR_2 PF13591.6 OAJ22176.1 - 8.1 6.4 11.0 5.6 6.9 0.4 3.5 2 1 1 3 3 3 0 MerR HTH family regulatory protein 4HBT PF03061.22 OAJ22177.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAJ22177.1 - 0.0047 17.2 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily S4 PF01479.25 OAJ22178.1 - 1.7e-13 50.0 0.0 3.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OAJ22178.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 S4 domain DUF5362 PF17319.2 OAJ22179.1 - 0.016 15.0 0.3 0.026 14.3 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5362) PIRT PF15099.6 OAJ22181.1 - 0.00013 21.5 1.2 0.00021 20.9 1.2 1.3 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family RIFIN PF02009.16 OAJ22181.1 - 0.0037 17.2 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 1 Rifin DUF2755 PF10954.8 OAJ22181.1 - 0.018 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) GT87 PF09594.10 OAJ22181.1 - 0.027 14.2 2.4 0.13 12.0 1.2 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 87 DAG1 PF05454.11 OAJ22181.1 - 0.045 13.1 0.8 0.11 11.9 0.0 1.9 2 1 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2567 PF10821.8 OAJ22181.1 - 0.062 13.4 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) CcmD PF04995.14 OAJ22181.1 - 0.18 11.9 1.4 0.34 11.0 1.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) C2 PF00168.30 OAJ22182.1 - 3.2e-13 49.9 0.0 9.7e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain Ras PF00071.22 OAJ22184.1 - 4.4e-45 153.2 0.0 1.5e-42 144.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAJ22184.1 - 1.2e-31 109.4 0.1 2e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ22184.1 - 1.7e-11 43.9 0.0 2.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ22184.1 - 0.00018 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ22184.1 - 0.00025 21.1 0.0 0.00048 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ22184.1 - 0.026 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAJ22184.1 - 0.14 11.7 0.1 0.83 9.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_luciferase PF00296.20 OAJ22185.1 - 4.4e-60 203.8 1.2 5.9e-60 203.3 1.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Yae1_N PF09811.9 OAJ22186.1 - 8.6e-07 28.6 8.5 2.1e-06 27.3 8.5 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 OAJ22186.1 - 0.0028 17.4 0.2 0.29 11.0 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med17 PF10156.9 OAJ22209.1 - 0.057 12.1 0.0 0.074 11.7 0.0 1.0 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Ndc1_Nup PF09531.10 OAJ22210.1 - 4.8e-21 75.1 33.1 8.7e-10 37.9 11.8 3.9 3 2 1 4 4 4 3 Nucleoporin protein Ndc1-Nup Na_Ca_ex PF01699.24 OAJ22213.1 - 3.6e-17 62.7 29.3 7.7e-11 42.2 15.8 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 OAJ22213.1 - 3.1e-15 56.6 5.1 3.1e-15 56.6 5.1 3.8 3 0 0 3 3 3 1 Inner membrane component domain Rtf2 PF04641.12 OAJ22213.1 - 1.2 8.5 8.4 2.8 7.2 8.4 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger DEAD PF00270.29 OAJ22214.1 - 3.2e-48 163.8 0.0 2e-47 161.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22214.1 - 1e-29 103.1 0.0 2.5e-28 98.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Ctf8 PF09696.10 OAJ22215.1 - 7.5e-14 52.3 2.5 5.6e-05 23.5 0.0 3.4 2 2 1 3 3 3 3 Ctf8 Rotavirus_VP1 PF12289.8 OAJ22220.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain Tetraspanin PF00335.20 OAJ22220.1 - 0.45 10.2 0.1 0.45 10.2 0.1 1.6 2 1 0 2 2 2 0 Tetraspanin family Exostosin PF03016.15 OAJ22222.1 - 0.15 11.3 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Exostosin family FMO-like PF00743.19 OAJ22224.1 - 9.8e-23 80.4 0.0 2.5e-22 79.0 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ22224.1 - 5.2e-13 48.9 0.4 9.5e-11 41.5 0.3 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ22224.1 - 6.6e-12 45.3 1.3 9.1e-09 34.9 1.4 2.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ22224.1 - 1.4e-09 37.6 2.3 1.9e-07 30.5 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ22224.1 - 1e-08 35.2 1.0 6.5e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ22224.1 - 8.1e-06 26.3 3.3 0.017 15.7 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 OAJ22224.1 - 1.2e-05 24.8 0.9 0.047 13.0 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAJ22224.1 - 1.7e-05 23.8 0.1 0.015 14.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAJ22224.1 - 2.9e-05 23.8 8.3 0.0003 20.5 1.7 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ22224.1 - 0.00027 21.0 4.7 0.014 15.4 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 OAJ22224.1 - 0.0003 20.1 2.9 0.012 14.9 0.5 2.6 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.24 OAJ22224.1 - 0.00093 18.6 0.2 0.22 10.7 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAJ22224.1 - 0.0021 17.5 0.1 0.085 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAJ22224.1 - 0.0043 17.5 0.0 0.58 10.6 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 OAJ22224.1 - 0.0067 16.3 0.4 0.013 15.4 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAJ22224.1 - 0.0094 15.1 0.6 0.0094 15.1 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 OAJ22224.1 - 0.014 15.5 0.2 2.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAJ22224.1 - 0.016 14.3 3.4 1.4 7.9 0.5 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAJ22224.1 - 0.095 11.7 0.2 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 OAJ22224.1 - 0.44 9.7 1.4 3.2 6.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain LRR_8 PF13855.6 OAJ22225.1 - 7.4e-17 60.9 16.5 4e-10 39.3 7.5 4.6 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 OAJ22225.1 - 1.4e-13 50.8 16.9 1.4e-05 25.3 2.4 5.9 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) Torus PF16131.5 OAJ22225.1 - 5.1e-09 36.8 5.2 5.6e-05 23.8 0.6 3.2 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 OAJ22225.1 - 4.5e-07 29.6 6.4 0.00091 19.1 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAJ22225.1 - 1.7e-06 27.7 8.0 0.0001 22.0 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ22225.1 - 0.0001 22.2 16.9 0.011 15.8 3.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ22225.1 - 0.0003 21.0 0.5 0.00064 19.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger containing family LRR_6 PF13516.6 OAJ22225.1 - 0.0011 18.8 14.9 11 6.3 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.33 OAJ22225.1 - 0.016 15.7 10.9 66 4.7 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich Repeat NUP214 PF16755.5 OAJ22225.1 - 0.016 14.5 0.1 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 MFS_1 PF07690.16 OAJ22226.1 - 1.4e-41 142.6 36.8 1.4e-41 142.6 36.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ22226.1 - 2.5e-05 22.9 3.1 4.2e-05 22.2 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PhrC_PhrF PF11131.8 OAJ22227.1 - 0.13 11.9 0.3 0.39 10.3 0.3 1.8 1 0 0 1 1 1 0 Rap-phr extracellular signalling Abhydrolase_3 PF07859.13 OAJ22228.1 - 2.1e-48 165.0 0.1 3.4e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ22228.1 - 3.9e-13 49.0 0.0 8.1e-13 48.0 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase PBP1_TM PF14812.6 OAJ22228.1 - 0.16 12.3 2.6 0.48 10.8 2.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ22228.1 - 0.72 10.3 6.4 2 8.8 6.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ22228.1 - 2.4 7.4 5.3 5.2 6.3 5.3 1.5 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ22228.1 - 9.1 4.2 6.3 14 3.6 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi CSN8_PSD8_EIF3K PF10075.9 OAJ22229.1 - 6.3e-27 94.3 0.0 1.2e-26 93.4 0.0 1.5 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family PP2C PF00481.21 OAJ22230.1 - 4.4e-67 226.4 0.2 1.5e-51 175.5 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C E3_UbLigase_RBR PF18091.1 OAJ22230.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 E3 Ubiquitin Ligase RBR C-terminal domain Forkhead PF00250.18 OAJ22231.1 - 7.1e-24 83.9 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain eIF_4EBP PF05456.11 OAJ22231.1 - 0.014 15.3 0.7 0.014 15.3 0.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) EPL1 PF10513.9 OAJ22231.1 - 0.97 9.8 9.1 0.37 11.1 3.5 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like TFIIA PF03153.13 OAJ22231.1 - 1.2 9.0 34.9 0.033 14.2 17.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 OAJ22231.1 - 2 7.4 10.7 0.084 11.9 2.5 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 OAJ22231.1 - 5.9 6.0 15.5 1.3 8.2 4.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DASH_Dad3 PF08656.10 OAJ22232.1 - 4.7e-18 65.0 0.2 6e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DinB_2 PF12867.7 OAJ22233.1 - 0.031 14.8 0.1 0.048 14.2 0.1 1.4 1 0 0 1 1 1 0 DinB superfamily MDMPI_N PF11716.8 OAJ22233.1 - 0.067 13.9 0.0 0.12 13.1 0.0 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain AAA_9 PF12781.7 OAJ22234.1 - 1.8e-74 249.6 4.4 6.1e-74 247.9 0.1 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 OAJ22234.1 - 4.4e-45 154.2 3.8 9.1e-45 153.2 3.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 OAJ22234.1 - 6.3e-41 140.6 0.9 9e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OAJ22234.1 - 1.6e-37 128.8 0.0 4.1e-37 127.5 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OAJ22234.1 - 6.1e-29 100.5 0.0 7.7e-28 97.0 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OAJ22234.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DUF948 PF06103.11 OAJ22234.1 - 0.3 11.4 6.4 17 5.8 0.6 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAJ22234.1 - 0.81 8.5 33.3 0.012 14.5 12.1 3.6 4 0 0 4 4 4 0 Spc7 kinetochore protein LOH1CR12 PF10158.9 OAJ22234.1 - 3.2 7.8 6.2 1.1 9.2 0.4 3.0 3 0 0 3 3 3 0 Tumour suppressor protein ERM PF00769.19 OAJ22234.1 - 7 6.4 29.0 0.76 9.5 12.9 3.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Sugar_tr PF00083.24 OAJ22235.1 - 3.9e-66 223.8 14.5 3.3e-39 135.0 1.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ22235.1 - 1.4e-19 70.2 34.9 2.6e-15 56.2 11.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1641 PF07849.11 OAJ22235.1 - 0.11 12.4 0.7 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) zf-CCCH PF00642.24 OAJ22236.1 - 1.7e-17 62.8 14.9 1.2e-10 41.0 2.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ22236.1 - 5.7e-07 29.4 14.3 3.6e-06 26.9 3.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ22236.1 - 0.00079 19.2 1.2 0.00079 19.2 1.2 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger SUIM_assoc PF16619.5 OAJ22236.1 - 0.0099 15.9 8.4 1.5 8.9 3.4 3.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_2 PF14608.6 OAJ22236.1 - 0.16 12.5 0.2 0.16 12.5 0.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Uso1_p115_head PF04869.14 OAJ22237.1 - 2.9e-43 148.2 0.0 1e-38 133.3 0.0 3.7 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAJ22237.1 - 5.4e-10 39.7 39.8 5.4e-10 39.7 39.8 3.6 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 OAJ22237.1 - 0.0048 16.9 2.3 0.078 13.0 0.0 3.3 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain ATG16 PF08614.11 OAJ22237.1 - 1.5 9.0 43.1 0.035 14.3 32.3 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.19 OAJ22237.1 - 2 8.2 40.3 4.4 7.0 40.3 1.7 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.6 OAJ22237.1 - 2 7.7 29.5 1 8.7 3.9 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 OAJ22237.1 - 2.4 7.8 24.4 0.22 11.2 8.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF812 PF05667.11 OAJ22237.1 - 3.3 6.5 23.2 5.4 5.8 23.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4094 PF13334.6 OAJ22237.1 - 4.7 7.7 10.5 1.9 8.9 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF966 PF06136.13 OAJ22237.1 - 4.8 6.8 19.6 8.9 5.9 19.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) EMG1 PF03587.14 OAJ22238.1 - 6.8e-77 257.5 0.0 8.4e-77 257.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3498 PF12004.8 OAJ22238.1 - 0.51 9.5 0.0 0.51 9.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) RabGAP-TBC PF00566.18 OAJ22240.1 - 7.5e-51 172.8 0.0 9.7e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Acetyltransf_10 PF13673.7 OAJ22241.1 - 5.1e-07 29.7 0.0 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 OAJ22241.1 - 0.00025 21.7 0.0 0.0013 19.4 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ22241.1 - 0.0012 19.2 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ22241.1 - 0.0078 16.4 0.0 0.041 14.1 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family BAR PF03114.18 OAJ22242.1 - 8.2e-12 45.3 1.8 1.3e-11 44.6 1.8 1.3 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 OAJ22242.1 - 0.0021 17.8 0.4 0.0035 17.1 0.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family BAR_2 PF10455.9 OAJ22242.1 - 0.0022 17.2 0.2 0.0037 16.4 0.2 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4349 PF14257.6 OAJ22242.1 - 0.025 14.0 2.2 0.053 13.0 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3053 PF11254.8 OAJ22242.1 - 0.18 11.4 0.6 0.31 10.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Med10 PF09748.9 OAJ22243.1 - 1.1e-17 64.1 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex ASH PF15780.5 OAJ22245.1 - 1.5e-15 57.1 0.1 7.6e-05 22.8 0.2 6.3 6 1 0 6 6 6 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 OAJ22245.1 - 2.1e-06 27.9 2.7 0.053 13.8 0.2 4.9 5 1 1 6 6 6 2 Transmembrane protein 131-like PapD-like PF14874.6 OAJ22245.1 - 1.7e-05 24.9 0.1 0.039 14.1 0.2 4.3 4 0 0 4 4 4 1 Flagellar-associated PapD-like FixG_C PF11614.8 OAJ22245.1 - 0.0039 17.4 1.8 1.3 9.3 0.2 4.4 5 0 0 5 5 5 1 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF1573 PF07610.11 OAJ22245.1 - 0.0084 16.1 0.3 0.32 11.1 0.0 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) DUF1090 PF06476.12 OAJ22245.1 - 0.25 11.5 2.6 0.74 10.0 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) NUDIX PF00293.28 OAJ22247.1 - 2.3e-25 89.1 0.0 3.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AA_permease PF00324.21 OAJ22248.1 - 7.1e-122 407.4 36.6 8.9e-122 407.1 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ22248.1 - 3.2e-35 121.8 41.2 3.7e-35 121.6 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 OAJ22248.1 - 4 8.2 11.4 1.4 9.7 0.1 3.9 3 0 0 3 3 3 0 PrgI family protein CSTF2_hinge PF14327.6 OAJ22249.1 - 1.3e-29 102.5 5.0 1.3e-29 102.5 5.0 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAJ22249.1 - 3.8e-22 77.9 0.0 5.6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAJ22249.1 - 8.1e-17 60.5 3.1 8.1e-17 60.5 3.1 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OAJ22249.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif CPSF_A PF03178.15 OAJ22250.1 - 1.8e-47 162.2 0.0 2.8e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ22250.1 - 5.6e-25 87.9 0.0 1.3e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Zn_clus PF00172.18 OAJ22251.1 - 1.6e-06 28.1 9.3 2.8e-06 27.3 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_synthFbeta PF17759.1 OAJ22252.1 - 1.6e-44 151.9 0.0 4.4e-44 150.5 0.0 1.7 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAJ22252.1 - 4.1e-29 100.6 0.0 1.3e-27 95.8 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAJ22252.1 - 2.2e-27 95.8 0.0 4.2e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAJ22252.1 - 1.3e-20 73.4 0.0 8.3e-18 64.4 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain HTH_33 PF13592.6 OAJ22252.1 - 0.21 11.3 0.0 0.59 9.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix Slu7 PF11708.8 OAJ22253.1 - 1.4e-103 346.4 22.0 1.4e-103 346.4 22.0 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor SR-25 PF10500.9 OAJ22253.1 - 0.0001 22.0 30.3 0.0001 22.0 30.3 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Nop53 PF07767.11 OAJ22253.1 - 0.67 9.3 37.9 0.54 9.6 13.8 2.3 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Elongin_A PF06881.11 OAJ22254.1 - 7.9e-26 90.6 0.4 1.1e-25 90.2 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Thioredoxin_4 PF13462.6 OAJ22255.1 - 3.4e-06 27.3 0.0 0.00022 21.4 0.0 2.5 1 1 0 1 1 1 1 Thioredoxin LysM PF01476.20 OAJ22279.1 - 0.0004 20.4 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 LysM domain WD40 PF00400.32 OAJ22280.1 - 2.7e-16 59.6 19.2 3.1e-07 31.0 0.7 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ22280.1 - 6.1e-07 29.7 0.2 0.87 9.9 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Bundlin PF05307.11 OAJ22280.1 - 0.32 10.9 1.8 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Bundlin Methyltransf_23 PF13489.6 OAJ22281.1 - 8.5e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ22281.1 - 4e-06 27.4 0.2 2.4e-05 24.9 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22281.1 - 1.9e-05 24.5 0.1 4.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ22281.1 - 9.2e-05 22.3 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OAJ22281.1 - 0.027 15.2 0.1 0.076 13.8 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ22281.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 OAJ22281.1 - 0.037 14.0 0.2 0.099 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22281.1 - 0.043 14.5 0.2 0.14 12.8 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ22281.1 - 0.054 14.5 0.0 0.14 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 OAJ22281.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 OAJ22281.1 - 0.17 11.4 0.1 0.52 9.8 0.1 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PAS PF00989.25 OAJ22282.1 - 0.00028 20.9 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 OAJ22282.1 - 0.00046 20.2 10.9 0.00046 20.2 10.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SBDS PF01172.18 OAJ22283.1 - 5.6e-15 55.2 0.1 7.3e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ABA_GPCR PF12430.8 OAJ22284.1 - 2.2e-34 118.8 6.7 5.5e-34 117.5 6.7 1.7 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAJ22284.1 - 7.8e-14 51.5 0.9 7.8e-14 51.5 0.9 2.0 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal Synaptonemal_3 PF15191.6 OAJ22284.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 FAD_binding_1 PF00667.20 OAJ22285.1 - 3.6e-55 186.9 0.0 5.5e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAJ22285.1 - 7.1e-33 113.8 0.1 1.4e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAJ22285.1 - 3.5e-20 72.7 0.0 1.7e-19 70.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1275 PF06912.11 OAJ22286.1 - 9.8e-30 103.9 12.3 1.3e-29 103.6 12.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4212 PF13937.6 OAJ22286.1 - 1.6 9.1 5.3 3.6 8.0 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF5379 PF17350.2 OAJ22286.1 - 2.1 8.7 8.9 0.075 13.3 2.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5379) Pro_isomerase PF00160.21 OAJ22287.1 - 3.2e-47 160.7 0.3 5.7e-47 159.9 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4366 PF14283.6 OAJ22287.1 - 0.0076 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF4958 PF16319.5 OAJ22287.1 - 0.052 11.5 0.0 0.071 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4958) MmgE_PrpD PF03972.14 OAJ22291.1 - 1e-144 482.4 0.6 1.3e-144 482.1 0.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nup54 PF13874.6 OAJ22292.1 - 1.1e-24 87.1 1.2 3.4e-23 82.3 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 OAJ22292.1 - 0.0029 18.4 77.8 33 5.4 57.1 4.7 3 1 0 3 3 3 1 Nucleoporin FG repeat region Nup54_C PF18437.1 OAJ22292.1 - 0.0083 16.0 0.2 0.0083 16.0 0.2 2.2 2 1 0 2 2 2 1 Nup54 C-terminal interacting domain TFIIA PF03153.13 OAJ22292.1 - 2.5 8.0 10.8 4.2 7.3 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ22292.1 - 3.7 7.1 8.9 6 6.4 8.9 1.3 1 0 0 1 1 1 0 Spt20 family Cyclin_N PF00134.23 OAJ22293.1 - 5.1e-09 35.9 0.0 1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ22293.1 - 0.00023 21.6 0.0 0.00023 21.6 0.0 3.0 3 0 0 3 3 3 1 Cyclin DUF3138 PF11336.8 OAJ22293.1 - 5.4 5.5 8.4 9 4.8 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SET PF00856.28 OAJ22294.1 - 1.1e-16 61.7 0.0 1.7e-15 57.8 0.0 2.4 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OAJ22294.1 - 6.8e-06 26.7 4.4 9.7e-06 26.2 2.3 2.1 2 0 0 2 2 2 1 Pre-SET motif SAF PF08666.12 OAJ22294.1 - 0.0033 18.0 0.0 0.048 14.3 0.0 2.3 2 0 0 2 2 2 1 SAF domain Methyltransf_23 PF13489.6 OAJ22295.1 - 1.5e-17 64.0 0.2 2.1e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22295.1 - 7e-15 55.4 0.1 6.5e-14 52.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ22295.1 - 4.2e-14 53.0 0.3 1.2e-12 48.3 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22295.1 - 6.9e-14 51.9 0.0 9.4e-13 48.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ22295.1 - 1.3e-13 51.5 0.0 1.3e-12 48.3 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAJ22295.1 - 3e-05 23.6 0.1 0.0049 16.4 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ22295.1 - 4.1e-05 23.0 0.1 0.0002 20.8 0.1 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 OAJ22295.1 - 0.0054 16.4 0.1 0.059 13.0 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) TPMT PF05724.11 OAJ22295.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FAM110_C PF14160.6 OAJ22295.1 - 0.077 14.1 0.0 0.28 12.3 0.0 1.9 1 1 1 2 2 2 0 Centrosome-associated C terminus DREV PF05219.12 OAJ22295.1 - 0.091 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase SelP_N PF04592.14 OAJ22295.1 - 0.33 10.3 19.6 0.65 9.4 19.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CoA_transf_3 PF02515.17 OAJ22296.1 - 8e-63 212.8 0.0 1.4e-62 212.0 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III TPR_1 PF00515.28 OAJ22297.1 - 7.5e-21 73.0 0.5 9.4e-07 28.4 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ22297.1 - 1.5e-20 71.6 8.8 1.9e-05 24.4 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ22297.1 - 2.7e-13 49.0 3.1 0.012 15.7 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22297.1 - 1.3e-12 47.4 8.8 0.0029 18.3 0.1 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ22297.1 - 4.3e-11 42.3 7.9 0.0049 16.5 0.1 4.8 3 1 2 5 5 4 3 TPR repeat TPR_19 PF14559.6 OAJ22297.1 - 3.8e-10 40.1 4.0 0.0062 17.0 0.2 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ22297.1 - 2.9e-08 33.6 2.6 0.00044 20.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22297.1 - 4.1e-08 33.4 8.1 0.0053 17.0 2.9 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ22297.1 - 7.9e-08 32.8 14.2 0.00024 21.7 0.2 4.5 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ22297.1 - 0.00049 19.9 7.9 0.95 9.6 0.0 4.6 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ22297.1 - 0.0022 18.1 4.3 0.031 14.4 0.2 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 OAJ22297.1 - 0.0037 17.7 10.4 0.29 11.6 1.1 4.0 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 OAJ22297.1 - 0.0044 17.3 7.6 0.6 10.5 0.1 4.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ22297.1 - 0.0062 17.1 12.5 12 6.8 0.0 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ22297.1 - 0.014 15.6 2.8 0.037 14.2 0.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 OAJ22297.1 - 0.064 13.3 0.8 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_glycop PF00913.19 OAJ22297.1 - 0.085 12.1 1.0 0.15 11.3 1.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) TPR_15 PF13429.6 OAJ22297.1 - 0.094 11.9 3.6 3 7.0 1.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 OAJ22297.1 - 0.18 11.2 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.6 OAJ22297.1 - 0.25 11.3 12.7 1.2 9.2 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAJ22297.1 - 0.46 10.4 4.5 7.5 6.4 0.0 3.1 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ATG13 PF10033.9 OAJ22298.1 - 1e-37 130.2 0.0 1.5e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Pex26 PF07163.12 OAJ22298.1 - 0.24 10.7 0.2 0.41 9.9 0.2 1.3 1 0 0 1 1 1 0 Pex26 protein Nuc_sug_transp PF04142.15 OAJ22299.1 - 5.3e-66 222.9 4.2 2.8e-48 164.7 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 OAJ22299.1 - 0.0022 18.1 2.6 0.0022 18.1 2.6 3.6 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 OAJ22299.1 - 0.86 8.9 5.5 0.13 11.6 0.3 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family OSCP PF00213.18 OAJ22300.1 - 4.9e-39 134.2 0.6 5.9e-39 134.0 0.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PALP PF00291.25 OAJ22301.1 - 1.7e-66 224.6 0.2 1.7e-66 224.6 0.2 1.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme zf-CCCH_2 PF14608.6 OAJ22302.1 - 5.8e-12 45.6 36.9 0.0012 19.2 1.4 5.3 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 OAJ22302.1 - 0.013 15.2 2.4 0.013 15.2 2.4 3.2 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_4 PF18044.1 OAJ22302.1 - 5.9 6.8 17.5 16 5.5 0.0 5.4 5 0 0 5 5 5 0 CCCH-type zinc finger SNF2_N PF00176.23 OAJ22303.1 - 1.1e-62 211.8 0.5 1.7e-62 211.2 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ22303.1 - 2.6e-19 69.6 0.0 6.3e-19 68.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 OAJ22303.1 - 2.1e-17 63.3 1.9 2.1e-17 63.3 1.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 OAJ22303.1 - 2.3e-13 49.8 1.3 1.4e-08 34.5 0.4 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OAJ22303.1 - 2e-11 44.2 0.1 9.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 OAJ22303.1 - 1.4e-05 25.7 0.3 8.4e-05 23.2 0.3 2.4 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 OAJ22303.1 - 0.00058 20.2 0.1 0.00058 20.2 0.1 4.2 4 0 0 4 4 4 1 Chromodomain helicase DNA-binding domain 1 SWI2_SNF2 PF18766.1 OAJ22303.1 - 0.017 14.8 0.0 0.11 12.2 0.0 2.3 1 1 0 1 1 1 0 SWI2/SNF2 ATPase SLIDE PF09111.10 OAJ22303.1 - 0.017 15.1 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 SLIDE TRAPP PF04051.16 OAJ22304.1 - 4.4e-35 120.6 0.0 5.8e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GCSF PF16647.5 OAJ22304.1 - 0.0028 17.5 0.2 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 Granulocyte colony-stimulating factor MetallophosN PF16371.5 OAJ22304.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase S36_mt PF10937.8 OAJ22305.1 - 6.4e-09 37.4 7.4 3.4e-08 35.1 7.4 1.8 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Polysacc_deac_2 PF04748.13 OAJ22306.1 - 0.098 11.8 0.1 0.098 11.8 0.1 2.3 3 0 0 3 3 3 0 Divergent polysaccharide deacetylase Myco_arth_vir_N PF09610.10 OAJ22307.1 - 0.092 12.8 0.6 0.15 12.2 0.6 1.3 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Adenylsucc_synt PF00709.21 OAJ22308.1 - 4.2e-174 579.4 0.0 4.8e-174 579.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase SIKE PF05769.11 OAJ22309.1 - 7.7e-05 22.7 11.4 0.00045 20.2 5.4 2.6 2 0 0 2 2 2 2 SIKE family Nop14 PF04147.12 OAJ22309.1 - 0.005 15.1 41.3 0.015 13.6 41.3 1.7 1 0 0 1 1 1 1 Nop14-like family Cadherin_tail PF15974.5 OAJ22309.1 - 0.22 11.8 3.7 0.48 10.8 3.7 1.5 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region VIR_N PF15912.5 OAJ22309.1 - 2.1 7.9 22.2 0.35 10.4 18.4 1.6 2 0 0 2 2 2 0 Virilizer, N-terminal Myco_arth_vir_N PF09610.10 OAJ22310.1 - 0.1 12.7 0.6 0.15 12.2 0.6 1.2 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) AAA PF00004.29 OAJ22311.1 - 0.0011 19.4 0.1 0.01 16.2 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 OAJ22311.1 - 0.029 14.4 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 OAJ22311.1 - 0.035 14.5 0.1 0.21 12.0 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OAJ22311.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 OAJ22311.1 - 0.22 11.4 0.0 0.94 9.4 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain RIBIOP_C PF04950.12 OAJ22313.1 - 1e-85 287.7 1.0 1.5e-85 287.2 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ22313.1 - 9e-31 105.8 0.0 2.5e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 OAJ22313.1 - 4.4e-06 27.2 0.0 1.7e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ22313.1 - 6.9e-05 23.1 0.0 0.00026 21.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ22313.1 - 0.00017 21.8 2.0 0.00062 19.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 OAJ22313.1 - 0.00025 20.6 0.0 0.012 15.1 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OAJ22313.1 - 0.0038 17.0 0.1 0.011 15.5 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 OAJ22313.1 - 0.0046 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ22313.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 OAJ22313.1 - 0.015 15.4 0.1 0.06 13.4 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAJ22313.1 - 0.026 14.8 0.0 0.089 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ22313.1 - 0.03 13.9 0.0 0.096 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ22313.1 - 0.035 14.6 2.7 0.05 14.1 0.0 2.6 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.22 OAJ22313.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 OAJ22313.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAJ22313.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 OAJ22313.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Roc PF08477.13 OAJ22313.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAJ22313.1 - 0.14 12.1 0.5 0.73 9.7 0.0 2.3 3 0 0 3 3 2 0 RsgA GTPase cobW PF02492.19 OAJ22313.1 - 0.18 11.4 0.1 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 OAJ22313.1 - 0.29 11.7 0.1 0.29 11.7 0.1 2.4 2 0 0 2 2 1 0 AAA domain OsmC PF02566.19 OAJ22314.1 - 1.2e-17 64.2 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein DUF4211 PF13926.6 OAJ22315.1 - 1.3e-05 25.3 0.1 4.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) RRM_1 PF00076.22 OAJ22316.1 - 3.2e-16 58.9 0.0 4.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ22316.1 - 5.1e-05 23.3 0.0 7.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif GPI2 PF06432.11 OAJ22317.1 - 3.3e-73 246.6 4.4 9.3e-62 209.0 1.0 2.0 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase SLATT_fungal PF18142.1 OAJ22317.1 - 0.0065 16.5 1.8 0.016 15.2 0.3 2.3 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain TPR_10 PF13374.6 OAJ22318.1 - 2.2e-58 192.7 64.4 3.4e-06 26.8 0.3 15.6 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22318.1 - 7.2e-40 135.1 80.7 1.1e-07 32.1 2.6 14.0 7 4 7 14 14 13 12 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ22318.1 - 5e-17 60.6 44.1 0.27 11.4 0.2 15.4 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ22318.1 - 3.6e-12 45.5 39.2 0.3 11.4 0.1 13.9 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ22318.1 - 1.2e-09 37.5 22.7 0.87 9.5 0.0 12.6 14 0 0 14 14 14 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ22318.1 - 7.5e-08 32.6 33.0 0.2 11.7 0.6 6.6 2 2 2 6 6 6 5 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 OAJ22318.1 - 9.5e-08 31.6 50.2 0.31 11.2 0.2 13.5 15 0 0 15 15 13 5 Tetratricopeptide repeat TcdB_N PF12918.7 OAJ22318.1 - 2.9e-07 30.7 0.0 25 5.2 0.0 7.8 7 1 1 8 8 8 0 TcdB toxin N-terminal helical domain Pkinase_fungal PF17667.1 OAJ22318.1 - 5.3e-06 25.5 14.1 4.4 6.0 0.3 8.6 9 1 0 9 9 9 1 Fungal protein kinase NUC130_3NT PF08158.12 OAJ22318.1 - 0.00017 21.8 1.8 68 3.9 0.0 6.8 6 0 0 6 6 6 0 NUC130/3NT domain Desmo_N PF06771.11 OAJ22318.1 - 0.00098 19.4 0.0 4.8 7.6 0.0 5.7 3 1 1 5 5 5 1 Viral Desmoplakin N-terminus TPR_4 PF07721.14 OAJ22318.1 - 0.0025 18.3 36.0 10 7.1 2.1 12.6 14 0 0 14 14 13 0 Tetratricopeptide repeat PPR PF01535.20 OAJ22318.1 - 0.19 12.0 22.1 83 3.8 0.1 11.1 12 0 0 12 12 12 0 PPR repeat FG-GAP_2 PF14312.6 OAJ22318.1 - 0.21 11.9 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 FG-GAP repeat SHNi-TPR PF10516.9 OAJ22318.1 - 0.56 9.7 10.0 6.4 6.3 0.1 6.0 8 0 0 8 8 7 0 SHNi-TPR TPR_6 PF13174.6 OAJ22318.1 - 1 10.1 16.7 1.6e+02 3.3 0.0 10.1 12 1 0 12 12 10 0 Tetratricopeptide repeat PhoU_div PF01865.16 OAJ22318.1 - 1.9 7.7 6.0 15 4.8 0.2 3.7 5 0 0 5 5 5 0 Protein of unknown function DUF47 DUF5113 PF17140.4 OAJ22318.1 - 2.7 7.8 18.4 16 5.2 0.0 7.4 5 3 5 10 10 9 0 Domain of unknown function (DUF5113) Mad3_BUB1_II PF08171.11 OAJ22318.1 - 5 7.4 13.4 90 3.3 0.0 7.1 9 0 0 9 9 8 0 Mad3/BUB1 homology region 2 Trypan_glycop PF00913.19 OAJ22318.1 - 5.6 6.1 6.3 6.8 5.9 0.1 3.0 3 0 0 3 3 3 0 Trypanosome variant surface glycoprotein (A-type) MCCD1 PF15707.5 OAJ22319.1 - 0.095 13.2 1.5 0.34 11.4 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial coiled-coil domain protein 1 TylF PF05711.11 OAJ22319.1 - 0.18 11.0 0.0 0.24 10.7 0.0 1.1 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) PEPCK_ATP PF01293.20 OAJ22320.1 - 4.1e-215 714.8 0.0 4.9e-215 714.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 OAJ22320.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OAJ22320.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.17 OAJ22321.1 - 2.7e-28 98.4 0.4 3.9e-28 97.9 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding NOA36 PF06524.12 OAJ22321.1 - 9 5.5 6.0 15 4.8 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein MARVEL PF01284.23 OAJ22322.1 - 0.11 12.5 15.4 0.44 10.6 14.9 2.1 1 1 0 1 1 1 0 Membrane-associating domain HMG_box PF00505.19 OAJ22323.1 - 1.3e-12 47.9 2.6 4.3e-09 36.6 0.7 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ22323.1 - 6e-05 23.6 1.1 6e-05 23.6 1.1 2.4 2 1 0 2 2 2 1 HMG-box domain TFIIIC_delta PF12657.7 OAJ22324.1 - 7.9e-16 58.5 0.3 2.2e-15 57.1 0.2 1.9 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PI3_PI4_kinase PF00454.27 OAJ22325.1 - 1.4e-35 123.3 0.0 2.5e-35 122.5 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RNA_capsid PF03035.14 OAJ22325.1 - 3 7.8 7.3 0.23 11.5 2.0 1.8 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein K_oxygenase PF13434.6 OAJ22326.1 - 5.3e-90 302.0 0.0 1e-89 301.1 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ22326.1 - 2.8e-06 27.4 0.0 7.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ22326.1 - 0.039 13.2 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ22326.1 - 0.085 12.1 0.1 6.8 5.8 0.0 3.0 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase ABC_membrane PF00664.23 OAJ22327.1 - 2.3e-97 326.0 24.2 1.7e-49 168.9 3.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ22327.1 - 4.4e-62 208.6 0.0 2.9e-31 108.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ22327.1 - 3.7e-12 46.1 3.0 0.00013 21.5 0.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OAJ22327.1 - 1.6e-07 31.7 0.1 0.0034 17.5 0.0 3.3 4 0 0 4 4 3 2 Helicase HerA, central domain AAA_16 PF13191.6 OAJ22327.1 - 1.5e-06 28.7 2.4 0.066 13.6 0.1 4.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 OAJ22327.1 - 3.4e-06 26.7 0.1 0.094 12.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ22327.1 - 8.1e-06 26.2 0.1 2.8 8.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 OAJ22327.1 - 1e-05 24.9 0.0 0.2 10.9 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin PRK PF00485.18 OAJ22327.1 - 0.00057 19.7 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OAJ22327.1 - 0.0014 19.2 0.2 1.1 9.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain ABC_ATPase PF09818.9 OAJ22327.1 - 0.0018 17.1 0.2 0.72 8.6 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAJ22327.1 - 0.0022 17.9 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OAJ22327.1 - 0.0035 17.5 0.8 8.1 6.6 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ22327.1 - 0.0045 16.7 0.0 1.1 8.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 OAJ22327.1 - 0.0048 16.1 0.0 3.1 6.9 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 OAJ22327.1 - 0.0093 16.2 3.1 3.8 7.8 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.18 OAJ22327.1 - 0.012 15.0 0.0 0.61 9.4 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family APS_kinase PF01583.20 OAJ22327.1 - 0.013 15.4 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 OAJ22327.1 - 0.039 13.7 0.0 13 5.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain MeaB PF03308.16 OAJ22327.1 - 0.097 11.6 0.0 4 6.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 OAJ22327.1 - 0.4 11.1 3.1 35 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain Alpha-amylase_C PF02806.18 OAJ22328.1 - 2.1e-28 98.6 0.0 6.1e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OAJ22328.1 - 8.3e-15 55.2 0.0 2.5e-10 40.4 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OAJ22328.1 - 1.3e-13 51.1 0.0 4e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL6 PF14871.6 OAJ22328.1 - 0.027 14.6 0.1 0.079 13.1 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 F-box-like PF12937.7 OAJ22329.1 - 3.1e-05 23.8 0.1 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ22329.1 - 0.00031 20.5 0.0 0.003 17.4 0.0 2.2 2 0 0 2 2 2 1 F-box domain Dus PF01207.17 OAJ22330.1 - 6.7e-48 163.4 0.0 1e-47 162.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) 4HBT_3 PF13622.6 OAJ22331.1 - 4.5e-57 194.2 0.1 2e-55 188.8 0.1 2.1 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ22331.1 - 1.2e-21 76.9 0.0 4.9e-18 65.2 0.0 2.6 2 1 0 2 2 2 2 Acyl-CoA thioesterase W2 PF02020.18 OAJ22332.1 - 5.1e-18 65.0 0.0 5.1e-18 65.0 0.0 2.6 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon GidB PF02527.15 OAJ22332.1 - 0.1 11.9 0.1 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G ArfGap PF01412.18 OAJ22333.1 - 4.7e-16 58.9 0.1 3.6e-15 56.1 0.1 2.0 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zf-Nse PF11789.8 OAJ22335.1 - 3.4e-13 49.2 0.1 6.8e-13 48.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3246 PF11596.8 OAJ22335.1 - 0.0012 18.3 1.3 0.0012 18.3 1.3 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3246) U-box PF04564.15 OAJ22335.1 - 0.0024 18.0 0.1 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain DUF5065 PF16723.5 OAJ22335.1 - 0.0098 16.0 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5065) zf-C3HC4_4 PF15227.6 OAJ22335.1 - 0.083 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAJ22335.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pex16 PF08610.10 OAJ22336.1 - 1.8e-110 369.2 0.0 3.8e-110 368.1 0.0 1.5 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) KfrA_N PF11740.8 OAJ22336.1 - 0.13 12.9 1.2 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Pro_dh PF01619.18 OAJ22337.1 - 2.7e-53 181.4 0.0 1.3e-24 87.3 0.0 3.1 3 0 0 3 3 3 3 Proline dehydrogenase zf-C2H2 PF00096.26 OAJ22338.1 - 5.1e-10 39.3 11.8 0.013 15.9 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ22338.1 - 1.1e-08 35.2 9.4 0.016 16.0 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ22338.1 - 1.1e-07 31.9 13.5 0.0019 18.5 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAJ22338.1 - 1e-05 25.4 3.2 0.0015 18.5 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ22338.1 - 0.0099 16.1 5.6 0.28 11.5 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding SUIM_assoc PF16619.5 OAJ22338.1 - 0.056 13.5 8.8 0.35 11.0 8.8 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-met PF12874.7 OAJ22338.1 - 0.058 13.8 11.8 0.099 13.1 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OAJ22338.1 - 0.11 12.8 4.7 0.39 11.0 3.5 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2HC PF01530.18 OAJ22338.1 - 1.8 8.8 7.6 17 5.7 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2HC type Spt20 PF12090.8 OAJ22338.1 - 4.5 6.8 12.5 12 5.5 12.5 1.6 1 0 0 1 1 1 0 Spt20 family S-antigen PF05756.11 OAJ22339.1 - 8.4 6.8 7.6 27 5.2 4.7 2.5 2 0 0 2 2 2 0 S-antigen protein DUF2431 PF10354.9 OAJ22341.1 - 1.6e-41 142.4 0.0 2.5e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.6 OAJ22341.1 - 0.0029 17.9 0.6 0.0029 17.9 0.6 2.8 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 OAJ22341.1 - 0.004 17.2 2.9 0.016 15.2 0.1 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal FAM176 PF14851.6 OAJ22341.1 - 0.96 9.1 3.4 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 OAJ22341.1 - 7 5.3 5.1 11 4.6 3.5 1.8 2 0 0 2 2 2 0 Presenilin DPBB_1 PF03330.18 OAJ22342.1 - 8.1e-08 32.4 0.1 1.1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ22342.1 - 0.055 13.3 1.6 0.11 12.4 1.6 1.6 1 1 0 1 1 1 0 Barwin family zinc_ribbon_9 PF14369.6 OAJ22342.1 - 0.068 13.4 0.5 0.12 12.6 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon PPR_2 PF13041.6 OAJ22343.1 - 8.1e-14 51.6 0.9 0.0035 17.5 0.0 5.4 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.6 OAJ22343.1 - 5e-08 32.9 0.0 0.012 15.6 0.0 4.3 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 OAJ22343.1 - 3.7e-05 23.2 1.6 0.88 8.9 0.0 4.4 4 1 1 5 5 5 2 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 OAJ22343.1 - 0.0028 17.5 0.0 3.7 7.4 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial ATPase expression PPR PF01535.20 OAJ22343.1 - 0.0043 17.2 4.6 7.9 7.0 0.1 5.2 6 0 0 6 6 6 1 PPR repeat Death PF00531.22 OAJ22343.1 - 0.11 12.7 0.3 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Death domain AA_synth PF06684.11 OAJ22343.1 - 0.11 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 Amino acid synthesis PPR_1 PF12854.7 OAJ22343.1 - 0.14 11.9 0.6 40 4.0 0.1 4.0 4 0 0 4 4 4 0 PPR repeat Shisa PF13908.6 OAJ22343.1 - 7.6 6.7 5.7 1.2 9.3 0.3 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RTC PF01137.21 OAJ22344.1 - 1.2e-49 168.5 0.0 1.5e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OAJ22344.1 - 3e-33 114.4 0.0 5.2e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain FAM176 PF14851.6 OAJ22344.1 - 0.19 11.4 1.1 0.29 10.8 1.1 1.2 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.12 OAJ22344.1 - 1.9 8.2 6.7 2.7 7.7 6.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 OAJ22344.1 - 4.3 7.8 7.3 7.8 6.9 7.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ22344.1 - 4.3 6.6 6.8 6.1 6.1 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Na_H_Exchanger PF00999.21 OAJ22345.1 - 3.6e-66 223.5 32.8 4.6e-66 223.2 32.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SpoVAB PF13782.6 OAJ22345.1 - 0.16 12.2 0.2 0.16 12.2 0.2 3.3 4 0 0 4 4 4 0 Stage V sporulation protein AB Spt5_N PF11942.8 OAJ22345.1 - 8.7 7.4 6.9 6.5 7.8 5.0 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal UDPGP PF01704.18 OAJ22367.1 - 2.3e-25 89.1 0.0 2.5e-15 56.0 0.0 2.2 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase tRNA-synt_2c PF01411.19 OAJ22368.1 - 3.4e-213 709.2 0.0 5.3e-213 708.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAJ22368.1 - 3.4e-17 62.3 0.2 8.1e-17 61.1 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAJ22368.1 - 0.031 14.7 7.1 0.28 11.6 7.1 2.5 1 1 0 1 1 1 0 DHHA1 domain GramPos_pilinD1 PF16555.5 OAJ22368.1 - 1.6 8.9 8.2 0.12 12.5 1.1 2.2 2 0 0 2 2 2 0 Gram-positive pilin subunit D1, N-terminal domain cobW PF02492.19 OAJ22369.1 - 2e-50 170.8 4.5 1.3e-47 161.7 4.5 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAJ22369.1 - 1.1e-17 63.7 0.3 1.5e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAJ22369.1 - 0.011 15.7 0.2 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 OAJ22369.1 - 0.049 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 OAJ22369.1 - 0.086 12.4 0.7 3.3 7.2 0.2 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAJ22369.1 - 0.089 13.1 1.6 2.3 8.5 1.6 2.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 OAJ22369.1 - 0.095 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1_Xtn PF16897.5 OAJ22369.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Cdh1_DBD_1 PF18196.1 OAJ22369.1 - 0.19 12.1 1.1 19 5.6 0.1 3.0 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 YL1 PF05764.13 OAJ22369.1 - 1.6 8.8 6.2 3.6 7.6 6.2 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 OAJ22369.1 - 3.5 5.7 7.1 5.9 5.0 7.1 1.2 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_2 PF00152.20 OAJ22370.1 - 5.4e-74 249.1 0.0 6.8e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ22370.1 - 1.7e-11 43.9 0.0 5.5e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ22370.1 - 8.7e-08 31.9 0.0 0.00017 21.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ribosomal_60s PF00428.19 OAJ22370.1 - 6.8 7.3 18.4 7.6 7.2 0.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein ERCC4 PF02732.15 OAJ22371.1 - 0.017 15.3 0.1 0.17 12.1 0.0 2.4 2 1 0 2 2 2 0 ERCC4 domain SOBP PF15279.6 OAJ22371.1 - 0.66 10.5 4.4 1.4 9.5 4.4 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.11 OAJ22371.1 - 4.1 5.8 10.8 7.4 4.9 10.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 TraF PF13728.6 OAJ22371.1 - 8.9 6.1 9.4 18 5.1 9.4 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein RAP1 PF07218.11 OAJ22371.1 - 9.9 4.3 8.5 15 3.7 8.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Actin PF00022.19 OAJ22372.1 - 1.3e-46 159.0 0.0 1.7e-45 155.4 0.0 2.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ22372.1 - 0.012 14.5 0.0 0.039 12.8 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Pkinase PF00069.25 OAJ22373.1 - 9.3e-59 198.9 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22373.1 - 4.5e-38 131.0 0.0 5.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22373.1 - 1.5e-05 24.5 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ22373.1 - 0.0071 15.3 0.0 0.014 14.4 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ22373.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAJ22373.1 - 0.018 15.0 0.0 0.17 11.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RNA_pol_N PF01194.17 OAJ22374.1 - 1.3e-28 99.1 0.3 1.7e-28 98.7 0.3 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit PhoD PF09423.10 OAJ22375.1 - 2.4e-104 349.2 3.4 2.9e-104 348.8 3.4 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAJ22375.1 - 1.4e-26 92.8 0.4 3e-26 91.8 0.4 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAJ22375.1 - 3.3e-08 34.0 3.9 3.3e-08 34.0 3.9 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HNH_2 PF13391.6 OAJ22375.1 - 0.17 12.0 0.0 0.46 10.7 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease START PF01852.19 OAJ22376.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 START domain zf-4CXXC_R1 PF10497.9 OAJ22377.1 - 0.028 14.6 2.5 0.1 12.9 2.5 1.9 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 E1-E2_ATPase PF00122.20 OAJ22378.1 - 9.6e-37 126.3 18.6 6.5e-29 100.7 2.2 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ22378.1 - 5.9e-31 107.6 1.3 5.9e-31 107.6 1.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ22378.1 - 1.2e-18 68.2 0.0 4.3e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ22378.1 - 1.3e-14 53.6 0.2 3.3e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ22378.1 - 1.1e-11 44.6 0.0 3.1e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ22378.1 - 0.044 13.5 0.4 1.7 8.4 0.1 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase SpoU_methylase PF00588.19 OAJ22379.1 - 0.0067 16.6 0.0 0.0083 16.3 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family TFR_dimer PF04253.15 OAJ22381.1 - 3.1e-19 69.3 0.0 1.1e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ22381.1 - 7.7e-16 58.4 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ22381.1 - 1.7e-11 43.9 0.1 3.9e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 OAJ22381.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 GATase_5 PF13507.6 OAJ22382.1 - 1.1e-97 326.2 0.0 1.6e-97 325.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAJ22382.1 - 9.8e-42 142.7 2.3 9.2e-29 100.6 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAJ22382.1 - 7e-31 106.6 0.0 1.6e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAJ22382.1 - 2.8e-21 75.8 0.0 7.1e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain TPK_catalytic PF04263.16 OAJ22383.1 - 2.8e-27 95.2 0.0 4e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAJ22383.1 - 3.4e-10 39.5 0.0 5.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CENP-I PF07778.11 OAJ22383.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Mis6 Ferric_reduct PF01794.19 OAJ22384.1 - 3.5e-25 88.5 15.0 2e-24 86.1 13.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ22384.1 - 8.7e-19 68.2 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ22384.1 - 9.3e-11 41.8 0.1 3.5e-10 39.9 0.0 2.0 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ22384.1 - 0.00097 19.8 0.0 0.0099 16.5 0.0 2.2 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Phosducin PF02114.16 OAJ22387.1 - 3e-09 36.2 0.2 3.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Phosducin Cwf_Cwc_15 PF04889.12 OAJ22387.1 - 0.011 15.5 7.3 0.011 15.5 7.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GOLD_2 PF13897.6 OAJ22387.1 - 1.2 9.6 5.7 0.15 12.6 1.4 1.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TPR_2 PF07719.17 OAJ22388.1 - 0.00044 20.2 4.0 0.092 12.9 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 OAJ22388.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OAJ22388.1 - 0.0032 17.2 0.3 0.022 14.6 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat CybS PF05328.12 OAJ22389.1 - 1.1e-40 138.4 0.0 1.8e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ACOX PF01756.19 OAJ22390.1 - 1.6e-43 148.3 0.0 2.7e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAJ22390.1 - 6.2e-19 68.0 0.0 1.2e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OAJ22390.1 - 5.1e-11 43.2 0.0 1.7e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 OAJ22390.1 - 1.8e-09 38.0 2.3 3.8e-09 36.9 0.9 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain APG6_N PF17675.1 OAJ22390.1 - 0.071 13.6 0.6 0.071 13.6 0.6 2.1 3 0 0 3 3 3 0 Apg6 coiled-coil region RRT14 PF17075.5 OAJ22390.1 - 0.072 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 Endonuclease_5 PF04493.14 OAJ22391.1 - 4e-52 176.8 0.0 7.8e-52 175.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 OAJ22391.1 - 0.093 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Ion_trans PF00520.31 OAJ22392.1 - 0.0004 19.7 0.1 0.00065 19.0 0.1 1.3 1 1 0 1 1 1 1 Ion transport protein Ribosomal_L27e PF01777.18 OAJ22394.1 - 9.4e-38 128.5 1.3 1.4e-37 127.9 1.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAJ22394.1 - 0.00033 20.5 0.8 0.00064 19.6 0.8 1.5 1 0 0 1 1 1 1 KOW motif DHHC PF01529.20 OAJ22395.1 - 2.6e-30 105.3 0.0 2.6e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt20 PF12090.8 OAJ22395.1 - 0.0012 18.6 7.9 0.0017 18.0 7.9 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 OAJ22395.1 - 0.0018 17.3 5.0 0.0025 16.9 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SARAF PF06682.12 OAJ22395.1 - 0.015 15.0 0.7 0.015 15.0 0.7 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 OAJ22395.1 - 0.02 14.9 6.8 0.031 14.3 6.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 OAJ22395.1 - 7.9 7.5 8.2 11 7.1 5.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 OAJ22395.1 - 8.3 5.4 7.4 16 4.5 7.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein TFR_dimer PF04253.15 OAJ22396.1 - 1.8e-23 82.9 0.0 3.4e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ22396.1 - 1.5e-16 60.7 0.1 2.8e-16 59.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ22396.1 - 8.3e-12 45.0 0.3 2.2e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 PA domain SKIP_SNW PF02731.15 OAJ22397.1 - 1.6e-69 232.7 0.6 1.6e-69 232.7 0.6 1.9 2 0 0 2 2 2 1 SKIP/SNW domain Hydrolase_4 PF12146.8 OAJ22398.1 - 5.9e-43 146.8 0.0 9.9e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_transf_8 PF01501.20 OAJ22398.1 - 3.9e-10 39.7 0.0 8.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.7 OAJ22398.1 - 9.1e-10 39.5 0.1 2.9e-09 37.9 0.0 1.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ22398.1 - 3.7e-08 33.3 0.2 7.3e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Mannosyl_trans3 PF11051.8 OAJ22398.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Esterase PF00756.20 OAJ22398.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 OAJ22398.1 - 0.0035 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 OAJ22398.1 - 0.0041 16.6 0.0 0.34 10.4 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 OAJ22398.1 - 0.047 13.5 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.13 OAJ22398.1 - 0.074 12.9 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAJ22398.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein BCA_ABC_TP_C PF12399.8 OAJ22398.1 - 0.12 12.3 1.1 2.9 7.9 0.2 3.0 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter LCAT PF02450.15 OAJ22398.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Rep_fac-A_3 PF08661.11 OAJ22399.1 - 2.3e-27 95.4 0.0 2.6e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 MFS_1 PF07690.16 OAJ22400.1 - 6e-23 81.3 44.8 4.2e-13 49.0 30.3 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 OAJ22400.1 - 0.054 11.8 6.8 2 6.6 4.4 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Aminotran_4 PF01063.19 OAJ22401.1 - 1.7e-05 24.8 0.0 0.00027 20.9 0.0 2.4 1 1 0 1 1 1 1 Amino-transferase class IV Hamartin PF04388.12 OAJ22401.1 - 3.7e-05 22.6 20.4 0.00058 18.7 0.0 3.7 2 1 0 2 2 2 1 Hamartin protein Phlebovirus_NSM PF07246.11 OAJ22401.1 - 3.5 6.9 8.2 2.4 7.5 4.9 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Csm1_N PF18504.1 OAJ22401.1 - 9.4 6.7 16.7 2.8 8.3 0.0 4.7 2 1 2 5 5 5 0 Csm1 N-terminal domain Adaptin_binding PF10199.9 OAJ22401.1 - 10 6.8 27.4 0.32 11.6 12.0 3.5 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 EF-hand_6 PF13405.6 OAJ22402.1 - 6.2e-10 38.2 2.1 8.4e-05 22.2 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ22402.1 - 4.7e-08 32.0 5.7 0.00048 19.5 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OAJ22402.1 - 2e-07 31.4 5.3 2.8e-06 27.7 1.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ22402.1 - 0.0043 16.5 2.5 0.091 12.3 0.4 2.7 2 0 0 2 2 2 1 EF hand PRTP PF01366.18 OAJ22402.1 - 0.18 9.8 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein EF-hand_8 PF13833.6 OAJ22402.1 - 0.3 11.0 3.3 8.7 6.3 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair ATE_C PF04377.15 OAJ22403.1 - 1.2e-45 155.4 0.1 1.8e-45 154.9 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 OAJ22403.1 - 3.2e-25 88.3 0.7 7.2e-25 87.2 0.7 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus tRNA-synt_2 PF00152.20 OAJ22404.1 - 1.4e-85 287.1 0.1 2.4e-85 286.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ22404.1 - 8.5e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rad9_Rad53_bind PF08605.10 OAJ22404.1 - 0.024 14.8 0.2 0.042 14.0 0.2 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Mito_carr PF00153.27 OAJ22405.1 - 4.6e-60 199.6 10.6 1.3e-22 79.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAJ22405.1 - 6.7e-05 22.2 0.2 0.0005 19.4 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OAJ22405.1 - 0.00012 21.7 0.1 0.00066 19.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OAJ22405.1 - 0.0006 19.2 0.5 0.0023 17.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAJ22405.1 - 0.0081 16.6 0.1 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair Tubulin PF00091.25 OAJ22406.1 - 3.8e-65 219.8 0.0 5.4e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ22406.1 - 1e-45 154.9 0.0 1.6e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAJ22406.1 - 0.00035 20.3 0.0 0.0007 19.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ22406.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Flavokinase PF01687.17 OAJ22407.1 - 3.3e-30 104.6 0.0 4e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Abhydrolase_1 PF00561.20 OAJ22408.1 - 5e-14 52.6 0.0 4.3e-13 49.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ22408.1 - 3e-11 43.1 0.1 9.1e-11 41.5 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ22408.1 - 6.3e-10 40.0 0.0 1.5e-09 38.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 OAJ22408.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase STE2 PF02116.15 OAJ22408.1 - 0.0094 15.3 7.5 0.017 14.5 7.5 1.3 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Thioesterase PF00975.20 OAJ22408.1 - 0.026 14.6 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 OAJ22408.1 - 0.2 11.4 0.3 1.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cid2 PF09774.9 OAJ22409.1 - 3.3e-24 86.1 3.2 1.2e-23 84.3 3.2 1.9 1 1 0 1 1 1 1 Caffeine-induced death protein 2 UBA2_C PF16195.5 OAJ22409.1 - 2.1 9.1 11.3 0.079 13.7 5.2 1.8 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Metallophos PF00149.28 OAJ22411.1 - 0.0005 20.6 1.1 0.0005 20.6 1.1 2.6 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase YL1 PF05764.13 OAJ22411.1 - 0.0042 17.2 1.3 0.0066 16.6 1.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein PGA2 PF07543.12 OAJ22411.1 - 0.015 15.3 3.8 0.037 14.0 3.8 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 SPT6_acidic PF14632.6 OAJ22411.1 - 0.019 15.5 9.0 0.066 13.8 9.0 1.9 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PBP1_TM PF14812.6 OAJ22411.1 - 1 9.8 8.7 4 7.9 8.7 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAJ22411.1 - 2.2 6.5 5.4 3.3 5.9 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Response_reg PF00072.24 OAJ22412.1 - 4e-24 85.0 0.1 7.7e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ22412.1 - 1e-16 61.4 0.0 1.9e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ22412.1 - 4.4e-09 36.3 0.3 4.4e-09 36.3 0.3 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain 3HCDH_RFF PF18321.1 OAJ22412.1 - 0.057 13.9 0.1 0.62 10.5 0.0 2.9 3 0 0 3 3 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Forkhead PF00250.18 OAJ22413.1 - 1.5e-29 102.0 0.0 2.6e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain ALG11_N PF15924.5 OAJ22414.1 - 1e-83 280.5 0.0 1.4e-83 280.0 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAJ22414.1 - 6e-16 58.5 0.0 1.6e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ22414.1 - 1.1e-07 32.3 0.0 1.1e-06 29.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ22414.1 - 0.0065 16.5 0.2 0.015 15.3 0.2 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 OAJ22414.1 - 0.079 13.4 0.0 0.28 11.6 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferases group 1 Peptidase_M28 PF04389.17 OAJ22415.1 - 2.6e-17 63.2 0.0 4.9e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ22415.1 - 3.6e-13 49.4 0.0 9.4e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.15 OAJ22415.1 - 3.8e-13 49.6 0.0 7.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Nucleos_tra2_C PF07662.13 OAJ22416.1 - 2.8e-68 229.8 1.4 2.8e-68 229.8 1.4 1.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAJ22416.1 - 4.3e-17 62.5 7.5 4.3e-17 62.5 7.5 3.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus RFX_DNA_binding PF02257.15 OAJ22418.1 - 0.11 13.2 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Erythro-docking PF09277.11 OAJ22419.1 - 0.08 12.9 0.0 6 6.8 0.0 2.7 2 0 0 2 2 2 0 Erythronolide synthase, docking TIP49 PF06068.13 OAJ22420.1 - 1.5e-156 521.0 0.0 2.8e-156 520.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ22420.1 - 2.4e-20 72.4 0.1 6.6e-20 71.0 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ22420.1 - 1.7e-10 41.4 0.1 4e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ22420.1 - 2.6e-09 37.0 0.1 1.4e-05 24.8 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ22420.1 - 1.4e-07 31.8 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ22420.1 - 4.7e-05 23.4 0.2 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ22420.1 - 0.00031 21.1 0.0 0.0027 18.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OAJ22420.1 - 0.00033 20.9 0.1 0.00072 19.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ22420.1 - 0.00089 19.6 3.1 0.065 13.6 3.1 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ22420.1 - 0.0038 16.7 0.1 0.27 10.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 OAJ22420.1 - 0.0091 15.6 3.3 0.011 15.4 0.3 2.4 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 OAJ22420.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAJ22420.1 - 0.017 14.8 0.1 2.8 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ22420.1 - 0.018 15.0 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 OAJ22420.1 - 0.031 14.0 0.1 0.09 12.5 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAJ22420.1 - 0.04 13.4 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OAJ22420.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 OAJ22420.1 - 0.074 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 OAJ22420.1 - 0.075 12.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 OAJ22420.1 - 0.13 11.6 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Glyco_transf_24 PF18404.1 OAJ22421.1 - 3.6e-143 475.8 1.3 5e-143 475.3 1.3 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAJ22421.1 - 1.4e-48 166.1 0.0 9.4e-48 163.4 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 OAJ22421.1 - 4.5e-35 121.2 0.1 4.2e-34 118.1 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAJ22421.1 - 4.8e-35 120.0 0.0 9e-35 119.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 OAJ22421.1 - 8.1e-32 110.9 0.0 2.5e-28 99.4 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAJ22421.1 - 1.6e-26 92.8 0.0 5e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OAJ22421.1 - 6.9e-05 22.5 0.2 0.00015 21.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 8 AMP-binding PF00501.28 OAJ22422.1 - 5.3e-72 242.7 0.0 3.2e-49 167.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ22422.1 - 5.6e-08 33.7 0.1 7.7e-07 30.0 0.0 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.18 OAJ22423.1 - 2.4e-43 148.3 0.0 3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase F-box-like PF12937.7 OAJ22424.1 - 0.00043 20.1 0.1 0.00097 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like WES_acyltransf PF03007.16 OAJ22425.1 - 1.7e-17 64.1 0.3 3e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ22425.1 - 1.2e-08 35.1 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Herpes_BLLF1 PF05109.13 OAJ22425.1 - 9.1 4.1 10.6 13 3.6 10.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Cyto_heme_lyase PF01265.17 OAJ22426.1 - 2e-41 142.5 5.2 3.2e-39 135.3 0.3 2.4 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase PX PF00787.24 OAJ22427.1 - 7e-22 77.5 0.6 1.9e-21 76.1 0.6 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAJ22427.1 - 3.6e-05 23.4 4.4 0.18 11.4 0.1 3.6 4 0 0 4 4 4 2 Vps5 C terminal like ANAPC2 PF08672.11 OAJ22427.1 - 0.033 14.7 0.9 5.6 7.6 0.1 3.3 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 ATP11 PF06644.11 OAJ22429.1 - 2.3e-72 244.1 0.1 4.2e-72 243.2 0.0 1.4 1 1 1 2 2 2 1 ATP11 protein Lipase_GDSL_2 PF13472.6 OAJ22429.1 - 0.26 11.7 0.3 0.75 10.2 0.1 1.7 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family kleA_kleC PF17383.2 OAJ22429.1 - 1.2 9.5 3.5 0.86 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Peptidase_M14 PF00246.24 OAJ22430.1 - 6.2e-60 203.4 0.0 4.8e-59 200.5 0.0 2.2 1 1 0 1 1 1 1 Zinc carboxypeptidase EIF4E-T PF10477.9 OAJ22430.1 - 7.1 5.3 11.2 9.9 4.8 11.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Sel1 PF08238.12 OAJ22431.1 - 5.4e-16 58.7 28.6 0.00012 22.7 0.1 8.3 9 0 0 9 9 9 4 Sel1 repeat TPR_12 PF13424.6 OAJ22431.1 - 0.023 15.0 0.0 20 5.5 0.1 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ22431.1 - 0.087 13.5 6.8 13 6.7 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3316 PF11777.8 OAJ22431.1 - 0.11 12.6 0.2 0.23 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) TPR_1 PF00515.28 OAJ22431.1 - 0.18 11.7 0.8 10 6.2 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3328 PF11807.8 OAJ22431.1 - 0.49 10.1 2.2 0.74 9.5 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) TPR_2 PF07719.17 OAJ22431.1 - 0.74 10.1 0.0 0.74 10.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RFX_DNA_binding PF02257.15 OAJ22432.1 - 6e-18 65.3 0.0 9.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain POT1PC PF16686.5 OAJ22433.1 - 1.3e-16 60.9 0.1 1.1e-15 57.8 0.1 2.2 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAJ22433.1 - 1.8e-10 40.8 0.0 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 zinc_ribbon_2 PF13240.6 OAJ22433.1 - 0.00065 19.3 2.8 0.0013 18.4 2.8 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 OAJ22433.1 - 0.0047 16.9 0.2 0.01 15.8 0.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 OAJ22433.1 - 0.0056 16.0 4.2 0.012 15.0 4.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain REPA_OB_2 PF16900.5 OAJ22433.1 - 0.08 12.9 0.0 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Replication protein A OB domain 2OG-FeII_Oxy_2 PF13532.6 OAJ22434.1 - 9.1e-15 55.4 0.0 2.6e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 OAJ22434.1 - 0.027 15.0 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TPR_1 PF00515.28 OAJ22435.1 - 6.4e-19 66.9 0.0 4.8e-05 23.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ22435.1 - 6.8e-15 53.9 0.6 0.00076 19.4 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ22435.1 - 3.6e-14 52.2 0.2 0.007 16.0 0.0 4.9 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 OAJ22435.1 - 1.4e-11 43.6 0.1 0.0034 17.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22435.1 - 2.1e-10 40.5 10.5 0.05 14.4 0.0 6.7 5 2 2 7 7 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ22435.1 - 1e-09 38.1 0.5 0.011 16.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ22435.1 - 3.4e-09 36.1 0.0 0.057 13.5 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ22435.1 - 4.8e-07 30.2 1.8 0.1 13.1 0.0 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22435.1 - 7.7e-07 29.3 0.7 0.00065 19.9 0.0 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ22435.1 - 3.7e-05 24.3 15.2 0.072 13.7 0.5 6.0 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ22435.1 - 0.0004 20.5 6.4 0.66 10.2 0.0 4.2 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ22435.1 - 0.019 14.8 3.1 0.14 12.1 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ22435.1 - 0.02 15.2 8.4 0.19 12.1 0.4 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Coprogen_oxidas PF01218.18 OAJ22455.1 - 2.4e-125 417.2 0.0 5e-125 416.1 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase TRAPPC-Trs85 PF12739.7 OAJ22456.1 - 4e-106 355.4 0.1 5.3e-106 355.0 0.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 OAJ22456.1 - 0.00039 17.9 0.0 0.00064 17.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit HHH PF00633.23 OAJ22457.1 - 0.0014 18.4 0.4 0.009 15.8 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 OAJ22457.1 - 0.038 14.6 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Raftlin PF15250.6 OAJ22457.1 - 2.4 6.8 9.1 3.9 6.1 9.1 1.2 1 0 0 1 1 1 0 Raftlin CAML PF14963.6 OAJ22457.1 - 3 7.9 7.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand TMF_TATA_bd PF12325.8 OAJ22458.1 - 0.00047 20.4 0.3 0.00063 20.0 0.3 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 OAJ22458.1 - 0.0022 18.4 1.5 0.02 15.3 0.2 2.0 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.11 OAJ22458.1 - 0.0025 18.1 3.0 0.003 17.8 3.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 OAJ22458.1 - 0.0032 16.8 3.5 0.0038 16.6 3.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cob_adeno_trans PF01923.18 OAJ22458.1 - 0.0052 16.9 0.1 0.006 16.7 0.1 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DHR10 PF18595.1 OAJ22458.1 - 0.006 16.6 5.5 0.0083 16.2 5.5 1.2 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain AAA_lid_9 PF17871.1 OAJ22458.1 - 0.0089 15.9 1.5 0.023 14.6 0.1 1.9 1 1 1 2 2 2 1 AAA lid domain Tropomyosin_1 PF12718.7 OAJ22458.1 - 0.0094 16.1 3.9 0.011 15.8 3.9 1.1 1 0 0 1 1 1 1 Tropomyosin like TACC_C PF05010.14 OAJ22458.1 - 0.023 14.5 1.1 0.49 10.1 1.5 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal bZIP_1 PF00170.21 OAJ22458.1 - 0.024 14.7 4.5 0.36 10.9 0.3 2.4 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 OAJ22458.1 - 0.038 14.4 3.6 1.1 9.7 3.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB ADIP PF11559.8 OAJ22458.1 - 0.043 13.9 4.5 0.47 10.5 0.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.13 OAJ22458.1 - 0.045 13.8 0.7 0.059 13.5 0.7 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BRE1 PF08647.11 OAJ22458.1 - 0.049 13.7 4.7 1 9.5 4.7 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Uds1 PF15456.6 OAJ22458.1 - 0.068 13.3 2.8 0.21 11.8 2.8 1.7 1 1 0 1 1 1 0 Up-regulated During Septation Bcr-Abl_Oligo PF09036.10 OAJ22458.1 - 0.12 12.4 0.1 2.8 8.0 0.2 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF4032 PF13224.6 OAJ22458.1 - 0.12 12.2 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4032) Spc7 PF08317.11 OAJ22458.1 - 0.13 11.1 2.0 0.18 10.7 2.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 OAJ22458.1 - 0.15 12.1 4.2 1.3 9.1 0.4 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Plk4_PB2 PF18409.1 OAJ22458.1 - 0.19 12.4 0.4 0.35 11.6 0.4 1.5 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 DMPK_coil PF08826.10 OAJ22458.1 - 0.23 11.6 4.5 0.15 12.2 0.9 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like BST2 PF16716.5 OAJ22458.1 - 0.24 12.0 4.9 2 9.1 0.5 2.1 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 OAJ22458.1 - 0.28 11.0 2.3 7 6.5 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.8 OAJ22458.1 - 0.51 10.4 8.2 1.3 9.1 0.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Csm1_N PF18504.1 OAJ22458.1 - 0.56 10.6 4.4 2.3 8.6 0.7 2.3 1 1 2 3 3 3 0 Csm1 N-terminal domain Nepo_coat_C PF03688.14 OAJ22459.1 - 0.058 13.3 0.1 0.3 10.9 0.0 1.9 1 1 1 2 2 2 0 Nepovirus coat protein, C-terminal domain RPEL PF02755.15 OAJ22460.1 - 8.6e-16 57.1 12.3 5.9e-06 25.8 2.4 3.8 3 1 0 3 3 3 3 RPEL repeat p450 PF00067.22 OAJ22461.1 - 3.3e-51 174.5 0.1 1e-49 169.6 0.1 2.9 1 1 0 1 1 1 1 Cytochrome P450 PPTA PF01239.22 OAJ22462.1 - 3.7e-40 134.5 3.9 3e-09 36.3 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 OAJ22462.1 - 0.0018 18.5 0.4 3.1 8.4 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22462.1 - 0.012 16.4 0.8 1.4 9.9 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad9 PF04139.13 OAJ22464.1 - 4e-33 114.9 0.0 9.2e-33 113.7 0.0 1.5 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.11 OAJ22464.1 - 5e-17 61.6 0.0 8.9e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 OAJ22464.1 - 0.0061 16.5 0.1 0.04 13.9 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin ICL PF00463.21 OAJ22465.1 - 3.1e-191 636.4 0.0 3.6e-191 636.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAJ22465.1 - 1.4e-09 37.8 0.0 3.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAJ22465.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain PSA_CBD PF18341.1 OAJ22465.1 - 0.085 12.9 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Trp_oprn_chp PF09534.10 OAJ22466.1 - 0.0028 17.5 1.6 0.0039 17.0 0.2 1.9 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MARVEL PF01284.23 OAJ22466.1 - 0.078 13.0 2.6 0.22 11.5 0.5 2.1 1 1 1 2 2 2 0 Membrane-associating domain WW PF00397.26 OAJ22467.1 - 1.9e-05 24.6 3.3 4.5e-05 23.5 3.3 1.7 1 0 0 1 1 1 1 WW domain RR_TM4-6 PF06459.12 OAJ22467.1 - 0.027 14.3 10.7 0.038 13.8 10.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 OAJ22467.1 - 0.16 11.7 2.8 0.22 11.3 2.8 1.1 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 OAJ22467.1 - 0.32 10.4 18.8 0.43 10.0 18.8 1.1 1 0 0 1 1 1 0 SDA1 Afi1 PF07792.12 OAJ22467.1 - 0.48 10.9 6.6 0.72 10.3 6.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Hid1 PF12722.7 OAJ22467.1 - 1.2 7.2 5.4 1.5 6.9 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIP PF07454.11 OAJ22467.1 - 1.4 8.3 7.2 2 7.8 7.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CENP-N PF05238.13 OAJ22467.1 - 1.7 7.9 5.8 2.3 7.4 5.8 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4407 PF14362.6 OAJ22467.1 - 2.4 7.4 7.6 3.3 7.0 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 OAJ22467.1 - 2.8 6.1 17.9 3.6 5.7 17.9 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 OAJ22467.1 - 4.7 6.5 24.0 6.9 6.0 24.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 OAJ22467.1 - 6.9 5.6 5.6 9.1 5.2 5.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 OAJ22467.1 - 8.7 5.2 9.0 11 4.9 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DNA_pol_E_B PF04042.16 OAJ22468.1 - 3.7e-47 160.4 0.2 5.1e-47 160.0 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FleQ PF06490.11 OAJ22468.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ DEAD_2 PF06733.15 OAJ22469.1 - 2.2e-49 167.4 0.1 1.5e-43 148.5 0.0 2.5 3 0 0 3 3 3 2 DEAD_2 Helicase_C_2 PF13307.6 OAJ22469.1 - 1.9e-44 151.8 0.0 3.9e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 OAJ22469.1 - 1.6e-41 142.1 0.8 6.1e-38 130.4 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 OAJ22469.1 - 0.00041 20.4 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ22469.1 - 0.027 14.2 0.0 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ22469.1 - 0.045 14.0 0.1 8.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Hom_end_hint PF05203.16 OAJ22471.1 - 0.02 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint PLA2_B PF01735.18 OAJ22472.1 - 3e-137 458.0 2.7 3.6e-137 457.7 2.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 OAJ22472.1 - 4.2e-05 23.8 0.3 0.00017 21.9 0.1 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase Metallophos PF00149.28 OAJ22473.1 - 2.1e-36 126.3 0.5 3e-36 125.8 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ22473.1 - 0.0015 18.9 0.1 0.003 18.0 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ22473.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Lyase_1 PF00206.20 OAJ22474.1 - 4.7e-93 312.0 0.0 7.2e-93 311.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAJ22474.1 - 2.4e-25 89.0 0.1 5.9e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal M20_dimer PF07687.14 OAJ22475.1 - 3.6e-09 36.5 0.1 7.5e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAJ22475.1 - 2.7e-05 24.0 0.3 5.1e-05 23.1 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4813 PF16072.5 OAJ22476.1 - 0.44 10.2 13.6 0.45 10.1 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RraA-like PF03737.15 OAJ22477.1 - 2.1e-35 122.1 0.0 3.3e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA DnaJ_C PF01556.18 OAJ22477.1 - 2.9e-31 108.6 0.0 5.3e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ22477.1 - 9e-24 83.4 0.4 1.5e-23 82.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ22477.1 - 2e-13 50.5 18.3 3.4e-13 49.7 18.3 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAJ22477.1 - 0.61 10.1 15.7 0.48 10.4 4.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein F-box-like PF12937.7 OAJ22478.1 - 6.8e-10 38.7 0.1 6.8e-10 38.7 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ22478.1 - 9.7e-06 25.3 2.9 1.8e-05 24.5 0.2 2.5 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.6 OAJ22478.1 - 0.0006 19.5 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OAJ22478.1 - 0.041 13.8 0.0 3.3 7.8 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat Phytase PF02333.15 OAJ22478.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Phytase ELO PF01151.18 OAJ22479.1 - 3.1e-54 184.2 3.1 3.9e-54 183.8 3.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LPD24 PF18839.1 OAJ22479.1 - 0.42 10.9 2.1 0.66 10.3 0.9 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 NatB_MDM20 PF09797.9 OAJ22480.1 - 3e-60 204.2 0.7 4.9e-60 203.5 0.1 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Med11 PF10280.9 OAJ22480.1 - 0.0088 16.5 0.7 0.083 13.4 0.0 2.6 2 0 0 2 2 2 1 Mediator complex protein TPR_16 PF13432.6 OAJ22480.1 - 0.022 15.4 1.6 0.022 15.4 1.6 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 OAJ22480.1 - 0.035 14.1 1.1 15 5.6 0.1 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Talin_middle PF09141.10 OAJ22480.1 - 0.054 13.5 5.1 0.097 12.7 2.1 2.7 2 0 0 2 2 2 0 Talin, middle domain TPR_19 PF14559.6 OAJ22480.1 - 1 9.9 17.7 13 6.4 0.8 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MoCF_biosynth PF00994.24 OAJ22481.1 - 6.3e-34 116.7 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Erp_C PF06780.11 OAJ22481.1 - 0.12 12.4 0.2 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus MaoC_dehydratas PF01575.19 OAJ22482.1 - 1.9e-25 88.8 0.0 5e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAJ22482.1 - 0.008 16.3 0.0 0.23 11.6 0.0 2.6 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Antimicrobial_5 PF08026.11 OAJ22482.1 - 1.4 9.1 6.3 0.34 11.0 1.8 2.3 2 0 0 2 2 2 0 Bee antimicrobial peptide CH PF00307.31 OAJ22483.1 - 4.7e-46 155.5 0.1 6.1e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAJ22483.1 - 2.2e-18 66.1 0.0 6.8e-18 64.5 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAJ22483.1 - 5.1e-11 42.3 0.1 4.5e-07 29.6 0.1 2.8 2 0 0 2 2 2 2 CAMSAP CH domain FAM76 PF16046.5 OAJ22483.1 - 0.029 13.7 0.3 0.043 13.2 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein EF-hand_6 PF13405.6 OAJ22483.1 - 0.044 13.7 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain Spc7 PF08317.11 OAJ22483.1 - 0.058 12.3 3.8 0.069 12.0 3.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OAJ22483.1 - 0.064 13.3 1.8 0.14 12.1 1.8 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspA_IM30 PF04012.12 OAJ22483.1 - 0.067 12.8 3.9 0.13 11.8 3.9 1.5 1 0 0 1 1 1 0 PspA/IM30 family Noelin-1 PF12308.8 OAJ22483.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein Spectrin PF00435.21 OAJ22483.1 - 0.13 12.7 3.6 0.33 11.4 0.4 2.9 2 1 0 2 2 2 0 Spectrin repeat HIP1_clath_bdg PF16515.5 OAJ22483.1 - 0.46 11.1 4.5 0.25 12.0 1.9 1.9 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 OAJ22483.1 - 0.68 10.0 5.0 0.27 11.3 1.0 2.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CAS_CSE1 PF03378.15 OAJ22484.1 - 1.1e-127 426.2 0.0 2.2e-127 425.3 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAJ22484.1 - 7.2e-121 403.5 0.0 1.2e-120 402.7 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAJ22484.1 - 1.5e-11 44.1 0.2 2e-08 34.0 0.2 4.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain NTP_transf_3 PF12804.7 OAJ22484.1 - 0.038 14.4 0.2 0.13 12.6 0.2 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain Xpo1 PF08389.12 OAJ22484.1 - 0.041 13.9 0.0 0.2 11.7 0.0 2.3 1 0 0 1 1 1 0 Exportin 1-like protein HEAT PF02985.22 OAJ22484.1 - 0.045 14.0 1.9 19 5.9 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat DUF1840 PF08895.11 OAJ22484.1 - 0.056 13.8 0.1 0.48 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Mit_ribos_Mrp51 PF11709.8 OAJ22485.1 - 0.0056 16.3 0.3 1.3 8.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein subunit zf-Mss51 PF13824.6 OAJ22486.1 - 5.9e-22 77.5 2.1 1.5e-21 76.2 2.1 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.18 OAJ22487.1 - 2.6e-160 533.3 13.5 3.3e-160 532.9 13.5 1.1 1 0 0 1 1 1 1 Calreticulin family DUF883 PF05957.13 OAJ22487.1 - 1.5 9.4 5.0 0.3 11.7 1.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TRAM_LAG1_CLN8 PF03798.16 OAJ22488.1 - 0.00093 19.0 12.5 0.0018 18.0 12.5 1.4 1 0 0 1 1 1 1 TLC domain DUF1282 PF06930.12 OAJ22488.1 - 0.13 12.0 6.0 0.24 11.2 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) GILT PF03227.16 OAJ22489.1 - 1.9e-14 53.8 0.1 3.5e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Aldedh PF00171.22 OAJ22491.1 - 3.5e-71 240.1 0.0 4.2e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 OAJ22492.1 - 4.5e-11 43.1 12.8 0.077 13.9 0.0 6.7 5 2 0 5 5 5 4 WD domain, G-beta repeat Senescence_reg PF04520.13 OAJ22492.1 - 0.07 14.0 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Senescence regulator HCNGP PF07818.13 OAJ22493.1 - 3e-19 69.5 0.0 6.2e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 HCNGP-like protein Paramyxo_ncap PF00973.19 OAJ22493.1 - 7.9 5.3 6.7 11 4.8 6.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glycos_transf_2 PF00535.26 OAJ22494.1 - 2.6e-32 112.0 0.0 3.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAJ22494.1 - 3.9e-13 49.8 0.0 5.7e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAJ22494.1 - 0.0002 20.9 0.0 0.00026 20.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ22494.1 - 0.0044 16.5 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 OAJ22494.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Sacchrp_dh_NADP PF03435.18 OAJ22495.1 - 2e-15 57.2 0.0 3.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAJ22495.1 - 5.9e-06 25.9 0.0 9.6e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ22495.1 - 1.9e-05 24.7 0.1 3.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ22495.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ22495.1 - 0.00059 18.9 0.0 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 OAJ22495.1 - 0.00084 19.0 0.1 0.0012 18.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 OAJ22495.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 OAJ22495.1 - 0.02 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 OAJ22495.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 OAJ22495.1 - 0.075 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 OAJ22495.1 - 0.14 11.3 0.2 1.2 8.2 0.1 2.3 2 1 0 2 2 2 0 Male sterility protein Vfa1 PF08432.10 OAJ22496.1 - 6.8e-33 114.5 0.0 9.3e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SseC PF04888.12 OAJ22496.1 - 0.078 12.6 5.6 0.11 12.1 5.6 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PV-1 PF06637.11 OAJ22496.1 - 0.08 11.8 3.0 0.14 11.0 3.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Activator-TraM PF11657.8 OAJ22496.1 - 0.52 10.1 4.5 0.89 9.4 4.5 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM MAPEG PF01124.18 OAJ22497.1 - 3.2e-13 49.7 5.7 4.1e-13 49.4 5.7 1.2 1 0 0 1 1 1 1 MAPEG family Solute_trans_a PF03619.16 OAJ22498.1 - 8e-80 268.2 13.2 9.9e-80 267.9 13.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha p450 PF00067.22 OAJ22499.1 - 2.6e-53 181.4 0.0 2.8e-52 178.0 0.0 2.4 1 1 0 1 1 1 1 Cytochrome P450 UPF0542 PF15086.6 OAJ22499.1 - 0.75 9.8 2.4 18 5.4 1.7 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 HAD PF12710.7 OAJ22500.1 - 1.4e-20 74.5 0.0 1.8e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 OAJ22500.1 - 3.8e-06 26.6 0.0 4.5e-05 23.1 0.0 2.1 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 OAJ22500.1 - 8.2e-05 22.1 0.4 0.00064 19.2 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 OAJ22500.1 - 8.8e-05 22.9 0.9 0.0022 18.3 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 OAJ22501.1 - 3.2e-44 150.8 0.8 2.3e-22 80.0 0.0 4.8 4 2 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 OAJ22501.1 - 4.1e-20 72.8 0.1 0.00048 20.0 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ22501.1 - 1.8e-15 57.0 1.5 0.0088 15.5 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ22501.1 - 3.7e-09 36.2 0.5 0.0031 17.2 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain CLASP_N PF12348.8 OAJ22501.1 - 5.7e-07 29.3 0.1 0.0058 16.2 0.0 2.5 1 1 1 2 2 2 2 CLASP N terminal AAA_23 PF13476.6 OAJ22501.1 - 4.9e-06 27.2 6.4 0.014 15.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OAJ22501.1 - 6.7e-06 26.4 0.0 0.69 10.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 OAJ22501.1 - 2.8e-05 24.1 0.0 0.048 13.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ22501.1 - 5.2e-05 23.3 0.0 0.34 11.0 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 OAJ22501.1 - 9.2e-05 22.3 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 OAJ22501.1 - 0.00011 22.4 0.8 0.037 14.1 0.2 3.1 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_18 PF13238.6 OAJ22501.1 - 0.00011 22.7 0.0 0.2 12.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OAJ22501.1 - 0.00029 20.8 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain G-alpha PF00503.20 OAJ22501.1 - 0.00045 19.5 0.0 0.41 9.7 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit HEAT_EZ PF13513.6 OAJ22501.1 - 0.00046 20.6 0.7 30 5.2 0.0 5.7 4 2 2 6 6 6 0 HEAT-like repeat HEAT PF02985.22 OAJ22501.1 - 0.00049 20.1 0.0 11 6.5 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat RNA_helicase PF00910.22 OAJ22501.1 - 0.00073 19.9 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 OAJ22501.1 - 0.00076 19.2 0.6 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 OAJ22501.1 - 0.00079 19.4 0.4 2.1 8.2 0.0 3.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OAJ22501.1 - 0.00096 19.6 0.1 0.79 10.1 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 OAJ22501.1 - 0.0012 19.2 0.0 0.63 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ22501.1 - 0.0013 18.9 0.0 2.5 8.3 0.0 3.1 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 OAJ22501.1 - 0.0014 19.0 0.2 0.22 11.9 0.0 4.2 4 1 2 6 6 5 1 HEAT repeats NB-ARC PF00931.22 OAJ22501.1 - 0.0015 17.8 0.0 0.86 8.7 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_13 PF13166.6 OAJ22501.1 - 0.0017 17.1 0.1 1.8 7.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain Chromo PF00385.24 OAJ22501.1 - 0.0023 17.8 0.1 0.0063 16.4 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 OAJ22501.1 - 0.0025 18.2 0.0 7.5 7.0 0.0 4.6 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) 4HB PF17947.1 OAJ22501.1 - 0.0031 17.5 0.0 0.015 15.4 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain SbcCD_C PF13558.6 OAJ22501.1 - 0.005 17.0 0.0 0.57 10.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 OAJ22501.1 - 0.0053 15.8 1.4 0.38 9.7 0.0 3.1 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OAJ22501.1 - 0.006 16.3 0.0 0.54 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 OAJ22501.1 - 0.022 15.0 0.0 6.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3584 PF12128.8 OAJ22501.1 - 0.024 12.2 4.4 0.48 7.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) TsaE PF02367.17 OAJ22501.1 - 0.039 14.0 0.2 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 OAJ22501.1 - 0.045 13.1 0.4 7.6 5.8 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 OAJ22501.1 - 0.051 13.6 1.9 11 6.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 OAJ22501.1 - 0.051 13.3 0.3 4.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 OAJ22501.1 - 0.071 12.7 0.3 14 5.3 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 OAJ22501.1 - 0.079 12.1 0.4 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAJ22501.1 - 0.079 12.9 0.0 10 6.0 0.1 2.8 3 0 0 3 3 2 0 NTPase AAA_25 PF13481.6 OAJ22501.1 - 0.095 12.3 0.0 4.2 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 OAJ22501.1 - 0.12 11.9 0.2 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L12_N PF16320.5 OAJ22502.1 - 0.97 9.2 7.7 24 4.7 0.0 4.0 4 0 0 4 4 4 0 Ribosomal protein L7/L12 dimerisation domain XPG_N PF00752.17 OAJ22503.1 - 1e-31 109.4 0.0 2e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ22503.1 - 3.3e-27 94.7 0.0 8.9e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAJ22503.1 - 0.00032 20.2 0.2 0.00087 18.8 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing HHH_5 PF14520.6 OAJ22503.1 - 0.15 12.7 0.8 0.6 10.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain NDUF_B8 PF05821.11 OAJ22504.1 - 1.1e-10 41.6 0.3 3.6e-10 40.0 0.3 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pkinase PF00069.25 OAJ22505.1 - 8.9e-64 215.4 1.6 9.6e-64 215.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22505.1 - 2e-42 145.3 0.0 4e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22505.1 - 2.8e-06 26.9 0.1 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ22505.1 - 0.054 12.3 0.0 0.054 12.3 0.0 2.7 3 0 0 3 3 3 0 Fungal protein kinase EPL1 PF10513.9 OAJ22505.1 - 0.086 13.2 15.0 2.5 8.4 5.7 3.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Spore_YhcN_YlaJ PF09580.10 OAJ22505.1 - 0.26 11.4 7.6 0.23 11.6 1.3 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Presenilin PF01080.17 OAJ22505.1 - 6.1 5.5 16.7 0.69 8.6 5.6 2.8 2 0 0 2 2 2 0 Presenilin CNH PF00780.22 OAJ22506.1 - 1.2e-08 34.9 0.0 4.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 OAJ22506.1 - 6.1e-06 26.6 0.2 6.1e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 TPR_14 PF13428.6 OAJ22506.1 - 0.95 10.5 4.4 71 4.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat HAT PF02184.16 OAJ22507.1 - 2.6e-17 62.5 52.5 2.9e-09 36.7 0.6 13.6 15 0 0 15 15 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OAJ22507.1 - 2.9e-14 52.5 33.2 0.0018 18.9 0.1 12.2 4 2 9 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ22507.1 - 3.2e-10 40.4 0.5 0.033 14.7 0.0 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 OAJ22507.1 - 2.1e-08 34.5 12.3 0.0017 18.4 0.1 5.1 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 OAJ22507.1 - 8.3e-05 22.4 8.4 27 5.2 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ22507.1 - 0.00042 20.3 3.2 3.4 8.1 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.11 OAJ22507.1 - 0.0039 16.3 2.2 0.38 9.9 0.2 2.8 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway TPR_17 PF13431.6 OAJ22507.1 - 0.021 15.2 0.1 2.2 8.9 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OAJ22507.1 - 0.05 13.7 11.3 0.28 11.3 0.6 4.8 3 2 2 5 5 5 0 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.12 OAJ22507.1 - 0.056 13.4 15.5 5.5 7.0 0.1 6.9 5 4 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 OAJ22507.1 - 0.056 13.3 2.0 2e+02 2.0 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 OAJ22507.1 - 2.5 8.5 17.1 3.3 8.2 7.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ22507.1 - 3 8.3 17.9 1.3 9.4 0.7 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ22507.1 - 8.9 5.5 11.8 1.2 8.4 3.2 2.2 2 0 0 2 2 2 0 NOA36 protein Copper-fist PF00649.18 OAJ22508.1 - 4.8e-14 51.6 1.0 4.8e-14 51.6 1.0 2.2 2 0 0 2 2 2 1 Copper fist DNA binding domain Vps5 PF09325.10 OAJ22509.1 - 9.7e-60 202.0 2.8 9.7e-60 202.0 2.8 2.6 2 1 0 2 2 2 1 Vps5 C terminal like RmlD_sub_bind PF04321.17 OAJ22509.1 - 3.3e-49 167.5 0.0 7.6e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain PX PF00787.24 OAJ22509.1 - 6.7e-22 77.6 0.0 3.1e-21 75.5 0.0 2.1 2 0 0 2 2 2 1 PX domain Epimerase PF01370.21 OAJ22509.1 - 1.8e-20 73.4 0.0 5.5e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ22509.1 - 4e-08 33.0 0.0 4e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAJ22509.1 - 2.1e-06 27.1 0.1 5.9e-05 22.3 0.0 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAJ22509.1 - 8.3e-06 25.2 0.0 0.00019 20.7 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein Peptidase_S10 PF00450.22 OAJ22510.1 - 1e-67 229.4 0.1 1.3e-67 229.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NAD_binding_5 PF07994.12 OAJ22511.1 - 1.8e-143 477.8 0.0 2.5e-143 477.3 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAJ22511.1 - 2.2e-42 143.7 0.2 6.3e-42 142.2 0.1 1.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase zf-U1 PF06220.12 OAJ22512.1 - 6.8e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 U1 zinc finger SelP_N PF04592.14 OAJ22512.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BTB PF00651.31 OAJ22513.1 - 6.2e-12 45.7 0.1 3.5e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain MATH PF00917.26 OAJ22513.1 - 0.15 12.2 0.0 0.66 10.2 0.0 2.0 2 0 0 2 2 2 0 MATH domain CP12 PF02672.15 OAJ22513.1 - 1.3 9.9 5.1 0.3 11.9 0.5 2.3 2 0 0 2 2 2 0 CP12 domain 2OG-FeII_Oxy_3 PF13640.6 OAJ22514.1 - 5.8e-08 33.5 0.0 1.1e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SLM4 PF16818.5 OAJ22515.1 - 0.12 12.3 0.2 0.42 10.6 0.2 1.9 1 0 0 1 1 1 0 Protein SLM4 PALP PF00291.25 OAJ22516.1 - 8.7e-62 209.2 0.4 1.7e-40 139.3 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme RIX1 PF08167.12 OAJ22537.1 - 1.5e-07 31.3 5.3 3.8e-07 30.1 0.3 2.8 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis Med14 PF08638.11 OAJ22538.1 - 3.6e-45 153.8 0.0 5.6e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 HMG_CoA_synt_N PF01154.17 OAJ22539.1 - 2.4e-83 278.3 0.3 5.1e-83 277.2 0.3 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 OAJ22539.1 - 2.2e-82 276.9 0.0 3e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal CBP4 PF07960.11 OAJ22540.1 - 8.4e-15 54.8 0.0 1e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 OAJ22540.1 - 0.018 15.0 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Kelch_4 PF13418.6 OAJ22541.1 - 5.7e-26 90.3 7.5 2.4e-10 40.2 0.0 6.1 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ22541.1 - 4e-18 65.2 6.9 7.6e-06 26.1 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ22541.1 - 1.1e-12 47.3 1.8 3.2e-05 23.4 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 OAJ22541.1 - 3.2e-12 46.3 3.3 0.002 18.4 0.2 5.5 4 1 1 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OAJ22541.1 - 6.9e-11 41.9 1.1 0.015 15.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAJ22541.1 - 0.0028 17.6 3.4 2.8 8.1 0.0 3.9 4 0 0 4 4 4 2 Kelch motif G-alpha PF00503.20 OAJ22542.1 - 9e-102 340.8 0.1 1e-101 340.7 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ22542.1 - 4.4e-12 45.8 0.2 1.7e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 OAJ22542.1 - 0.0087 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 OAJ22542.1 - 0.015 15.5 0.1 2 8.6 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ22542.1 - 0.018 15.1 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ22542.1 - 0.034 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 OAJ22542.1 - 0.051 13.4 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 OAJ22542.1 - 0.057 12.8 0.1 6.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MCM PF00493.23 OAJ22542.1 - 0.06 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 OAJ22542.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad1 PF02144.16 OAJ22543.1 - 3.6e-67 226.3 0.0 4.8e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CsbD PF05532.12 OAJ22544.1 - 4.1e-07 29.8 19.1 5.8e-05 22.9 5.7 3.0 1 1 1 2 2 2 2 CsbD-like ARPC4 PF05856.12 OAJ22545.1 - 8.1e-80 266.3 4.7 9e-80 266.1 4.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Med12 PF09497.10 OAJ22546.1 - 3e-25 88.3 0.0 8.6e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 MCM PF00493.23 OAJ22547.1 - 7.3e-97 322.9 0.0 1e-96 322.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ22547.1 - 5.9e-39 132.8 0.8 1.1e-38 132.0 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ22547.1 - 9.7e-27 93.2 1.5 9.7e-27 93.2 1.5 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ22547.1 - 1.1e-16 61.3 0.0 3.3e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ22547.1 - 3.5e-08 33.6 0.0 1.1e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ22547.1 - 6.2e-07 29.0 0.0 0.00017 21.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ22547.1 - 0.00012 21.9 0.0 0.0022 17.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ22547.1 - 0.005 17.2 0.4 0.028 14.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 OAJ22547.1 - 0.012 15.3 1.2 0.59 9.8 0.0 3.4 4 0 0 4 4 4 0 Sigma-54 interaction domain HSP90 PF00183.18 OAJ22548.1 - 1.9e-224 746.3 17.7 2.6e-224 745.9 17.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAJ22548.1 - 6.1e-15 55.7 0.0 1.3e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ22548.1 - 1e-09 38.3 0.1 1e-09 38.3 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 OAJ22548.1 - 0.064 13.2 0.1 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN DUF45 PF01863.17 OAJ22548.1 - 2.3 8.2 11.2 3.7 7.5 5.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 G-patch PF01585.23 OAJ22549.1 - 7e-14 51.5 1.7 1.6e-13 50.3 1.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 OAJ22549.1 - 0.00013 22.0 0.4 0.00013 22.0 0.4 3.6 3 1 0 3 3 3 1 G-patch domain TFIIF_alpha PF05793.12 OAJ22549.1 - 0.0009 18.0 33.3 0.0013 17.4 33.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 OAJ22549.1 - 0.053 12.1 13.5 0.06 11.9 13.5 1.3 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 OAJ22549.1 - 0.1 11.6 17.7 0.14 11.2 17.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 OAJ22549.1 - 0.28 9.5 29.3 0.57 8.4 29.3 1.5 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OAJ22549.1 - 0.65 8.8 20.3 0.88 8.4 20.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOBP PF15279.6 OAJ22549.1 - 1.4 9.5 23.2 2.2 8.8 23.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Red1 PF07964.11 OAJ22549.1 - 2.1 6.5 23.3 2.6 6.2 23.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Nop14 PF04147.12 OAJ22549.1 - 3 5.9 32.6 4 5.5 32.6 1.1 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 OAJ22549.1 - 4.2 4.4 16.5 4.9 4.2 16.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 OAJ22549.1 - 8.9 5.0 24.1 14 4.3 24.1 1.3 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 OAJ22549.1 - 9 4.9 17.1 13 4.4 17.1 1.2 1 0 0 1 1 1 0 Raftlin APG6 PF04111.12 OAJ22550.1 - 2.7e-65 219.7 0.0 4.9e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAJ22550.1 - 7.6e-25 88.0 19.7 8.2e-25 87.9 18.4 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region SOG2 PF10428.9 OAJ22550.1 - 0.011 15.0 6.0 0.016 14.4 6.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-C4H2 PF10146.9 OAJ22550.1 - 0.33 11.2 7.9 0.62 10.3 7.9 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_23 PF13476.6 OAJ22550.1 - 0.58 10.6 2.3 1 9.8 2.3 1.3 1 0 0 1 1 1 0 AAA domain JIP_LZII PF16471.5 OAJ22550.1 - 0.65 10.2 11.3 0.54 10.5 8.6 2.3 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II SOGA PF11365.8 OAJ22550.1 - 0.66 11.1 13.5 1.2 10.3 7.6 3.2 2 1 1 3 3 3 0 Protein SOGA YabA PF06156.13 OAJ22550.1 - 1.5 9.5 4.6 1.3 9.7 2.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Lyase_aromatic PF00221.19 OAJ22551.1 - 2.8e-150 501.0 7.6 3.9e-150 500.6 7.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase MAM33 PF02330.16 OAJ22552.1 - 7.2e-61 205.8 0.1 8.8e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Glyco_transf_41 PF13844.6 OAJ22553.1 - 1.3e-101 340.4 2.0 1.4e-47 162.2 0.0 4.2 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 OAJ22553.1 - 2.8e-19 68.1 0.1 6.8e-05 22.5 0.1 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ22553.1 - 3.3e-17 61.5 1.5 5.3e-05 23.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ22553.1 - 1.9e-16 59.4 7.0 8e-06 25.4 0.1 5.5 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.17 OAJ22553.1 - 5e-15 54.3 0.1 0.0031 17.5 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ22553.1 - 8.7e-12 44.3 0.0 0.0005 20.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ22553.1 - 5.9e-10 39.1 1.2 0.1 13.5 0.0 5.8 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ22553.1 - 9.1e-10 38.1 12.2 0.0014 18.4 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ22553.1 - 2.3e-08 34.2 0.0 0.53 10.6 0.0 4.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ22553.1 - 1.2e-07 32.1 0.0 0.13 12.8 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ22553.1 - 2.3e-06 27.2 0.1 0.078 13.0 0.0 4.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ22553.1 - 0.014 15.5 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PH PF00169.29 OAJ22554.1 - 0.00027 21.4 0.0 0.0021 18.5 0.0 2.3 1 1 0 1 1 1 1 PH domain FAM104 PF15434.6 OAJ22555.1 - 1.5 9.4 7.9 1.3 9.6 4.3 2.9 2 0 0 2 2 2 0 Family 104 RCC1 PF00415.18 OAJ22556.1 - 2.3e-39 133.8 2.5 5.7e-09 36.5 0.0 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ22556.1 - 3e-23 81.0 9.3 3.8e-06 26.5 0.0 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 OAJ22556.1 - 7e-11 41.9 9.8 7e-11 41.9 9.8 1.6 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 OAJ22556.1 - 0.019 14.9 4.4 0.13 12.1 1.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADK_lid PF05191.14 OAJ22556.1 - 0.02 14.9 1.2 0.051 13.6 1.2 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid PHD_2 PF13831.6 OAJ22556.1 - 0.2 11.3 4.3 0.057 13.0 0.7 2.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 OAJ22556.1 - 1.1 9.2 9.5 0.33 10.9 5.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 OAJ22556.1 - 4.8 7.4 10.5 18 5.5 10.5 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_4 PF16866.5 OAJ22556.1 - 6.1 7.0 9.9 16 5.7 9.9 1.7 1 0 0 1 1 1 0 PHD-finger DUF2834 PF11196.8 OAJ22557.1 - 0.35 11.2 8.4 4.5 7.7 1.6 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) YIF1 PF03878.15 OAJ22558.1 - 4.3e-90 301.4 0.0 5.6e-90 301.0 0.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAJ22558.1 - 0.095 12.4 14.5 0.013 15.2 7.4 2.3 1 1 0 2 2 2 0 Yip1 domain Ribosomal_L11_N PF03946.14 OAJ22558.1 - 5.7 6.8 9.0 0.2 11.5 1.2 2.4 2 1 1 3 3 3 0 Ribosomal protein L11, N-terminal domain SUV3_C PF12513.8 OAJ22559.1 - 7.3e-16 57.8 0.5 1.6e-15 56.8 0.5 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OAJ22559.1 - 3e-11 43.6 0.0 7.7e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDC45 PF02724.14 OAJ22559.1 - 0.92 7.7 7.6 1.6 6.9 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAJ22559.1 - 1.2 7.6 8.4 2.1 6.8 8.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNase_PH PF01138.21 OAJ22560.1 - 1.6e-33 116.0 0.1 2.3e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ22560.1 - 0.0024 17.9 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PPP4R2 PF09184.11 OAJ22561.1 - 2.6 7.5 6.9 3.7 7.0 6.9 1.2 1 0 0 1 1 1 0 PPP4R2 Mito_carr PF00153.27 OAJ22562.1 - 4.6e-09 36.1 0.1 0.016 15.1 0.0 3.7 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.19 OAJ22562.1 - 0.05 14.2 1.6 0.11 13.1 1.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Arrestin_C PF02752.22 OAJ22563.1 - 2e-14 54.2 0.0 1.1e-13 51.8 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ22563.1 - 4.3e-06 26.8 0.0 0.00058 19.9 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain TAFII28 PF04719.14 OAJ22564.1 - 1.8e-27 95.2 0.1 2.9e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF4770 PF15994.5 OAJ22564.1 - 0.041 14.1 1.6 0.069 13.4 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SRP_SPB PF02978.19 OAJ22564.1 - 0.12 13.0 0.8 0.24 12.1 0.8 1.5 1 0 0 1 1 1 0 Signal peptide binding domain CBFD_NFYB_HMF PF00808.23 OAJ22564.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SIR4_SID PF16991.5 OAJ22564.1 - 0.17 11.9 1.0 0.26 11.3 1.0 1.2 1 0 0 1 1 1 0 Sir4 SID domain CPSF100_C PF13299.6 OAJ22564.1 - 0.39 10.9 2.8 0.58 10.3 2.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GBP_C PF02841.14 OAJ22564.1 - 0.4 10.0 6.3 0.57 9.5 6.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3292 PF11696.8 OAJ22564.1 - 0.49 8.7 2.6 0.73 8.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CDC45 PF02724.14 OAJ22564.1 - 1.1 7.4 5.1 1.4 7.1 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3682 PF12446.8 OAJ22564.1 - 2.8 8.4 24.2 0.027 15.0 11.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Transferase PF02458.15 OAJ22566.1 - 1.7e-09 36.9 0.0 1e-07 31.0 0.0 2.8 2 1 0 2 2 2 2 Transferase family Transferase PF02458.15 OAJ22567.1 - 3.2e-09 36.0 0.0 6.9e-07 28.3 0.0 2.2 1 1 0 1 1 1 1 Transferase family CMD PF02627.20 OAJ22568.1 - 0.064 13.3 1.2 0.19 11.8 1.2 1.7 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family NAM-associated PF14303.6 OAJ22568.1 - 0.066 13.9 0.0 0.066 13.9 0.0 3.6 3 1 0 3 3 3 0 No apical meristem-associated C-terminal domain Na_Ca_ex PF01699.24 OAJ22569.1 - 1.1e-40 139.1 39.3 4.6e-21 75.4 12.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RNA_pol_Rpb4 PF03874.16 OAJ22570.1 - 8.9e-12 45.4 0.5 1.6e-11 44.6 0.5 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 AKAP2_C PF15304.6 OAJ22570.1 - 0.062 12.6 1.0 0.08 12.2 1.0 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus adh_short PF00106.25 OAJ22571.1 - 8.7e-20 71.0 0.0 4.9e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ22571.1 - 6.4e-12 45.5 0.0 1.2e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ22571.1 - 1.8e-07 31.3 0.1 3.3e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ22571.1 - 0.22 10.6 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Homeodomain PF00046.29 OAJ22572.1 - 7.8e-19 67.3 1.6 1.3e-18 66.6 1.6 1.4 1 0 0 1 1 1 1 Homeodomain tRNA-synt_1c PF00749.21 OAJ22573.1 - 5.5e-105 350.7 0.9 6.1e-105 350.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 OAJ22573.1 - 7.8e-37 126.8 0.0 1.8e-36 125.6 0.0 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 OAJ22573.1 - 5.8e-28 97.9 0.0 1.7e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 OAJ22573.1 - 2.9e-07 31.3 7.3 2.9e-07 31.3 7.3 2.8 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 zf-ANAPC11 PF12861.7 OAJ22575.1 - 1.5e-31 108.3 9.4 1.9e-31 108.0 9.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAJ22575.1 - 1.3e-19 70.2 14.2 1.9e-19 69.7 14.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ22575.1 - 2.2e-06 27.9 15.3 2e-05 24.8 15.3 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ22575.1 - 2.3e-05 24.2 11.8 8.9e-05 22.3 11.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ22575.1 - 0.0087 15.9 17.6 0.009 15.8 13.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 OAJ22575.1 - 0.29 11.3 9.0 0.1 12.7 6.7 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_11 PF17123.5 OAJ22575.1 - 0.63 9.8 13.5 8.7 6.2 13.5 2.3 1 1 0 1 1 1 0 RING-like zinc finger Ribosomal_S5 PF00333.20 OAJ22576.1 - 1.5e-29 101.7 0.5 3.7e-29 100.5 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ22576.1 - 9.9e-23 79.4 0.1 1.6e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAJ22576.1 - 4.3 8.0 9.7 9.2 6.9 9.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosom_S12_S23 PF00164.25 OAJ22577.1 - 8.6e-19 67.2 0.3 1.4e-18 66.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 OAJ22578.1 - 2.7e-26 91.4 0.1 1.3e-25 89.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S12/S23 PhoLip_ATPase_C PF16212.5 OAJ22578.1 - 9.6e-17 61.6 13.1 5.3e-15 55.8 2.1 2.1 2 0 0 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal YTV PF07639.11 OAJ22578.1 - 0.053 13.6 1.0 0.091 12.9 1.0 1.3 1 0 0 1 1 1 0 YTV Hydrolase_3 PF08282.12 OAJ22578.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3328 PF11807.8 OAJ22579.1 - 0.45 10.3 1.1 0.98 9.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) CHCH PF06747.13 OAJ22580.1 - 1.2e-07 31.7 4.1 2e-07 30.9 4.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 OAJ22580.1 - 0.026 14.9 5.3 0.043 14.2 5.3 1.4 1 0 0 1 1 1 0 GCK domain NAP PF00956.18 OAJ22582.1 - 8.3e-96 320.3 4.4 1.3e-95 319.6 4.4 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Apolipoprotein PF01442.18 OAJ22582.1 - 0.0079 16.1 0.8 0.023 14.6 0.8 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Cwf_Cwc_15 PF04889.12 OAJ22582.1 - 0.22 11.2 15.7 1.7 8.3 8.5 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MDD_C PF18376.1 OAJ22583.1 - 1.7e-69 233.4 0.0 2.1e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAJ22583.1 - 3.5e-06 27.2 2.9 8.1e-06 26.0 1.8 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain SPC22 PF04573.12 OAJ22584.1 - 1.1e-52 177.9 0.3 1.3e-52 177.8 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Glyco_transf_21 PF13506.6 OAJ22585.1 - 8.8e-24 83.9 0.3 9.3e-10 38.2 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAJ22585.1 - 8.1e-14 52.1 0.2 4e-12 46.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ22585.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Toprim_C_rpt PF13368.6 OAJ22585.1 - 0.19 11.8 0.1 1.1 9.3 0.3 2.1 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat Peptidase_C54 PF03416.19 OAJ22586.1 - 7.2e-100 333.9 0.0 1.2e-99 333.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 Sugar_tr PF00083.24 OAJ22587.1 - 2.1e-44 152.2 10.8 3.4e-44 151.5 10.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ22587.1 - 2.5e-25 89.2 23.6 3.1e-12 46.1 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3099 PF11298.8 OAJ22587.1 - 0.86 9.8 3.4 0.73 10.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) OATP PF03137.20 OAJ22587.1 - 6 5.0 7.7 0.87 7.8 0.1 2.9 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family PRA1 PF03208.19 OAJ22588.1 - 2.5e-33 114.7 0.1 3.1e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein YrhK PF14145.6 OAJ22588.1 - 5.9 6.8 10.4 0.29 11.0 1.4 2.4 2 1 0 2 2 2 0 YrhK-like protein IMS PF00817.20 OAJ22589.1 - 3.8e-45 153.5 0.2 6.4e-45 152.8 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ22589.1 - 3.3e-14 53.6 0.7 9.3e-14 52.1 0.4 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ22589.1 - 8.3e-06 25.8 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Gly-rich_Ago1 PF12764.7 OAJ22589.1 - 0.00066 20.4 6.7 0.00066 20.4 6.7 2.3 2 0 0 2 2 2 1 Glycine-rich region of argonaut UPF0172 PF03665.13 OAJ22590.1 - 2.1e-41 142.1 0.0 2.5e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) HSF_DNA-bind PF00447.17 OAJ22591.1 - 1.5e-30 105.6 0.7 2.7e-30 104.8 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2938 PF11158.8 OAJ22592.1 - 0.013 15.0 0.6 0.25 10.8 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2938) SRF-TF PF00319.18 OAJ22593.1 - 2.3e-21 75.0 0.0 4.3e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AhpC-TSA_2 PF13911.6 OAJ22594.1 - 4.9e-15 55.6 0.0 7.1e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ22594.1 - 0.018 14.8 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 Redoxin AhpC-TSA PF00578.21 OAJ22594.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Pyridoxal_deC PF00282.19 OAJ22595.1 - 7.6e-21 74.2 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ22595.1 - 1.9e-10 40.2 0.0 3.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAJ22595.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family UPF0220 PF05255.11 OAJ22596.1 - 4.2e-51 172.8 0.0 4.8e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) BRCT_2 PF16589.5 OAJ22597.1 - 3.3e-09 37.0 0.0 5.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ22597.1 - 2.4e-08 34.2 0.2 1.9e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ22597.1 - 6.9e-06 26.3 0.1 1.4e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 OAJ22597.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 OAJ22597.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Endonuc_Holl PF10107.9 OAJ22597.1 - 0.12 12.2 1.4 0.16 11.8 0.4 1.7 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase G-alpha PF00503.20 OAJ22598.1 - 3.8e-123 411.1 1.2 4.4e-123 410.9 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ22598.1 - 8.3e-17 61.2 0.7 1e-11 44.6 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ22598.1 - 2.1e-05 24.0 0.2 0.0044 16.4 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ22598.1 - 0.00061 20.0 0.1 1.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 OAJ22598.1 - 0.0033 17.2 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger MCM PF00493.23 OAJ22598.1 - 0.0078 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MMR_HSR1 PF01926.23 OAJ22598.1 - 0.022 14.8 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ22598.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.4 2 1 1 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ22598.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sacchrp_dh_NADP PF03435.18 OAJ22599.1 - 1e-06 29.0 0.0 7.9e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF1449 PF07290.11 OAJ22599.1 - 0.038 13.6 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DEAD PF00270.29 OAJ22600.1 - 1.9e-48 164.5 0.0 3.2e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ22600.1 - 2.6e-31 108.2 0.0 9.1e-31 106.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ22600.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ22600.1 - 0.12 11.7 0.6 0.2 11.0 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Arm PF00514.23 OAJ22601.1 - 1.3e-79 260.0 9.3 3.7e-11 42.7 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ22601.1 - 1.5e-22 79.7 6.2 6.6e-08 32.9 0.0 5.7 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 OAJ22601.1 - 5.3e-19 67.5 0.3 1.3e-18 66.3 0.3 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 OAJ22601.1 - 5.7e-16 58.7 6.7 2.3e-06 27.9 0.3 5.4 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 OAJ22601.1 - 7.4e-16 56.9 5.8 0.00039 20.4 0.0 7.2 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.20 OAJ22601.1 - 2.8e-14 53.3 0.9 5.5e-14 52.4 0.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.6 OAJ22601.1 - 1.6e-06 28.2 0.8 0.038 14.2 0.0 3.6 2 1 1 3 3 3 3 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 OAJ22601.1 - 0.002 18.7 0.1 3.6 8.5 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 OAJ22601.1 - 0.18 10.3 0.0 0.59 8.6 0.0 2.0 1 1 0 1 1 1 0 Adaptin N terminal region DUF2418 PF10332.9 OAJ22620.1 - 8.3e-22 77.5 0.7 8.3e-22 77.5 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) PPP4R2 PF09184.11 OAJ22620.1 - 0.00048 19.8 6.4 0.00075 19.2 6.4 1.3 1 0 0 1 1 1 1 PPP4R2 SDA1 PF05285.12 OAJ22620.1 - 0.23 10.8 19.2 0.34 10.3 19.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ22620.1 - 1.3 7.2 23.2 1.8 6.7 23.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ22620.1 - 1.4 8.2 16.8 2.5 7.3 16.8 1.4 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 OAJ22620.1 - 1.9 8.2 10.2 3.5 7.4 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 OAJ22620.1 - 2 7.1 4.4 3.3 6.4 4.4 1.5 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 OAJ22620.1 - 2.1 8.1 14.9 1.7 8.4 13.2 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RNA_pol_Rpc4 PF05132.14 OAJ22620.1 - 3 8.3 6.7 15 6.0 3.7 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 OAJ22620.1 - 4.6 5.2 29.9 6.6 4.7 29.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 OAJ22620.1 - 8.9 6.3 36.5 15 5.6 36.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ERAP1_C PF11838.8 OAJ22621.1 - 1.1e-68 232.2 0.0 1.8e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ22621.1 - 7.4e-65 218.6 0.0 1.1e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ22621.1 - 7.7e-16 58.8 0.7 2.3e-11 44.2 0.1 2.8 2 1 1 3 3 3 2 Peptidase M1 N-terminal domain MIF4G PF02854.19 OAJ22622.1 - 4.2e-52 176.9 0.4 3.7e-31 108.4 0.0 3.7 3 1 1 4 4 4 3 MIF4G domain Upf2 PF04050.14 OAJ22622.1 - 3.6e-23 82.8 6.0 6.3e-23 82.0 1.8 3.0 1 1 1 2 2 2 1 Up-frameshift suppressor 2 CDC45 PF02724.14 OAJ22622.1 - 0.00011 20.7 7.5 0.00023 19.6 7.5 1.5 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 OAJ22622.1 - 0.0079 16.3 15.7 0.0079 16.3 15.7 2.5 3 1 1 4 4 2 1 YL1 nuclear protein Nop14 PF04147.12 OAJ22622.1 - 0.012 13.8 24.0 0.03 12.6 24.0 1.6 1 0 0 1 1 1 0 Nop14-like family Dor1 PF04124.12 OAJ22622.1 - 0.039 12.6 1.3 0.092 11.4 1.3 1.6 1 0 0 1 1 1 0 Dor1-like family Presenilin PF01080.17 OAJ22622.1 - 0.25 10.1 1.4 0.46 9.2 1.4 1.3 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 OAJ22622.1 - 0.5 8.4 5.2 1.2 7.1 5.2 1.7 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Myc_N PF01056.18 OAJ22622.1 - 0.56 10.0 8.7 1.5 8.6 8.7 1.7 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 OAJ22622.1 - 1.1 7.3 36.0 2.7 6.0 36.0 1.6 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 OAJ22622.1 - 2.3 8.2 29.2 5.9 6.8 29.2 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BUD22 PF09073.10 OAJ22622.1 - 3.8 6.8 26.5 0.02 14.2 15.7 2.2 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 OAJ22622.1 - 4 6.8 30.2 0.039 13.4 22.0 1.7 2 0 0 2 2 2 0 SDA1 Pes-10 PF07149.11 OAJ22622.1 - 8.4 5.3 21.0 3.2 6.7 18.0 1.8 2 0 0 2 2 2 0 Pes-10 SAPS PF04499.15 OAJ22622.1 - 9.3 4.9 8.6 21 3.7 8.6 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zn_clus PF00172.18 OAJ22623.1 - 1.1e-05 25.4 7.2 1.8e-05 24.7 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Menin PF05053.13 OAJ22623.1 - 0.15 10.4 6.3 0.23 9.8 6.3 1.2 1 0 0 1 1 1 0 Menin PHD PF00628.29 OAJ22625.1 - 1.7e-06 27.8 7.4 4.2e-06 26.5 7.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 OAJ22625.1 - 0.52 10.6 4.1 0.84 9.9 1.3 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C2H2_4 PF13894.6 OAJ22625.1 - 8.6 7.5 6.1 11 7.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger rve PF00665.26 OAJ22626.1 - 0.0002 21.5 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DNA_gyraseB_C PF00986.21 OAJ22626.1 - 0.042 14.0 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Cwf_Cwc_15 PF04889.12 OAJ22627.1 - 0.01 15.6 10.8 0.01 15.6 10.8 2.5 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein rRNA_processing PF08524.11 OAJ22627.1 - 0.091 12.8 41.1 35 4.4 17.7 4.4 2 1 1 3 3 3 0 rRNA processing DNA_pol_phi PF04931.13 OAJ22627.1 - 0.51 8.4 21.2 0.7 7.9 21.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Rhodopsin_N PF10413.9 OAJ22628.1 - 0.18 11.7 0.2 0.38 10.6 0.2 1.5 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin Pep3_Vps18 PF05131.14 OAJ22630.1 - 1.3e-47 161.4 0.0 3.2e-47 160.1 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAJ22630.1 - 8.8e-07 28.9 8.5 4.4e-06 26.6 0.7 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 OAJ22630.1 - 0.00021 20.8 0.7 0.00072 19.1 0.7 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OAJ22630.1 - 0.0068 16.4 2.2 0.0068 16.4 2.2 1.9 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 OAJ22630.1 - 0.012 15.6 1.0 0.028 14.4 1.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 OAJ22630.1 - 0.027 14.8 1.3 0.027 14.8 1.3 2.1 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ22630.1 - 0.028 14.3 2.1 0.077 12.8 2.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RPN1_RPN2_N PF17781.1 OAJ22630.1 - 0.032 13.6 0.2 0.083 12.3 0.2 1.7 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Vps39_2 PF10367.9 OAJ22630.1 - 0.058 13.9 0.4 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 OAJ22630.1 - 0.15 12.4 1.8 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Terminase_5 PF06056.12 OAJ22630.1 - 0.16 11.9 0.4 0.45 10.4 0.4 1.8 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-rbx1 PF12678.7 OAJ22630.1 - 0.49 10.7 1.8 1.8 8.9 0.9 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Complex1_LYR PF05347.15 OAJ22631.1 - 0.043 13.9 0.7 0.14 12.3 0.7 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ22631.1 - 0.57 11.0 0.1 0.57 11.0 0.1 2.3 2 1 0 2 2 2 0 Complex1_LYR-like ABATE PF07336.11 OAJ22631.1 - 1 10.1 7.2 1.4 9.6 0.5 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator GMC_oxred_N PF00732.19 OAJ22632.1 - 5.8e-38 130.9 0.1 9.1e-37 127.0 0.1 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ22632.1 - 8e-29 101.0 0.0 1.3e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase S10_plectin PF03501.15 OAJ22633.1 - 1e-39 134.5 0.1 1.4e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Y_phosphatase2 PF03162.13 OAJ22634.1 - 5.6e-45 152.9 0.0 8.3e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.14 OAJ22634.1 - 2.6e-35 122.0 4.0 4.1e-35 121.4 4.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.6 OAJ22634.1 - 4.6e-06 26.8 0.0 8.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 OAJ22634.1 - 0.22 11.3 0.0 1 9.2 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Kinesin PF00225.23 OAJ22635.1 - 3e-110 368.3 0.0 4.5e-110 367.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ22635.1 - 6.2e-24 84.6 0.0 1.4e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Atg14 PF10186.9 OAJ22635.1 - 0.079 12.0 1.0 0.13 11.4 1.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GPS2_interact PF15784.5 OAJ22635.1 - 0.1 13.0 0.4 0.25 11.8 0.4 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FAM76 PF16046.5 OAJ22635.1 - 0.19 11.1 0.6 0.32 10.3 0.6 1.3 1 0 0 1 1 1 0 FAM76 protein Ribosomal_L29e PF01779.17 OAJ22636.1 - 8.1e-24 83.7 10.0 8.1e-24 83.7 10.0 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Trp_Tyr_perm PF03222.13 OAJ22636.1 - 0.18 10.8 0.1 0.23 10.5 0.1 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family DnaJ PF00226.31 OAJ22637.1 - 6e-16 58.3 1.2 1.2e-15 57.3 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain JAB PF01398.21 OAJ22638.1 - 1.6e-32 111.9 0.1 3.2e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ22638.1 - 2.3e-15 57.0 0.4 4.2e-15 56.1 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAJ22638.1 - 3.7e-06 26.7 0.0 6.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HXXSHH PF07586.11 OAJ22638.1 - 0.01 15.5 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF5624 PF18538.1 OAJ22638.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Acetyltransf_1 PF00583.25 OAJ22639.1 - 1.5e-15 57.5 0.0 1.8e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ22639.1 - 1.9e-05 25.0 0.0 2.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ22639.1 - 0.0022 18.7 0.0 0.0028 18.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ22639.1 - 0.025 14.5 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ22639.1 - 0.036 14.0 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DUF3602 PF12223.8 OAJ22640.1 - 1.4e-12 48.0 20.4 2e-08 34.7 4.8 3.9 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) PIG-F PF06699.11 OAJ22641.1 - 8e-11 42.4 0.7 8e-11 42.4 0.7 2.3 3 0 0 3 3 3 1 GPI biosynthesis protein family Pig-F Gaa1 PF04114.14 OAJ22641.1 - 1.9e-07 30.5 14.3 6.1e-07 28.8 2.6 2.3 1 1 0 2 2 2 2 Gaa1-like, GPI transamidase component VirB3 PF05101.13 OAJ22641.1 - 1.6 9.1 5.3 0.47 10.7 0.2 2.8 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein HABP4_PAI-RBP1 PF04774.15 OAJ22642.1 - 2.2e-12 47.8 3.3 2.2e-12 47.8 3.3 2.3 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family Cyclin_N PF00134.23 OAJ22643.1 - 1.3e-09 37.9 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain P2 PF07194.11 OAJ22643.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF2457 PF10446.9 OAJ22643.1 - 7.7 5.5 12.4 0.75 8.9 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) VRR_NUC PF08774.11 OAJ22644.1 - 2.7e-20 72.4 0.0 1.1e-19 70.5 0.0 2.1 1 0 0 1 1 1 1 VRR-NUC domain MOZ_SAS PF01853.18 OAJ22645.1 - 2e-75 252.4 0.1 2.8e-75 251.9 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ22645.1 - 7.4e-20 70.3 1.6 1.8e-19 69.1 1.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 OAJ22645.1 - 0.35 10.9 1.2 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger NUDIX PF00293.28 OAJ22646.1 - 4e-09 36.6 0.1 1.1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain VanY PF02557.17 OAJ22646.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase OPT PF03169.15 OAJ22647.1 - 1.9e-186 621.4 57.4 2.1e-186 621.2 57.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.19 OAJ22647.1 - 2.4 8.0 6.5 3.7 7.4 0.6 3.3 3 1 0 3 3 3 0 VIT family OPT PF03169.15 OAJ22648.1 - 1.1e-186 622.2 59.4 1.2e-186 622.0 59.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LHC PF00556.20 OAJ22648.1 - 0.016 15.4 8.4 4 7.7 1.5 5.0 3 0 0 3 3 3 0 Antenna complex alpha/beta subunit Pkinase PF00069.25 OAJ22649.1 - 1.8e-64 217.7 0.0 2.3e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22649.1 - 2e-33 115.7 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22649.1 - 5.7e-09 35.7 0.0 8.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ22649.1 - 0.00034 20.6 0.2 0.00082 19.4 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ22649.1 - 0.0009 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ22649.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ22649.1 - 0.0016 17.8 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ22649.1 - 0.065 12.8 0.2 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SOG2 PF10428.9 OAJ22650.1 - 4.7e-88 296.6 0.0 4.7e-88 296.6 0.0 5.1 3 2 1 4 4 4 1 RAM signalling pathway protein LRR_8 PF13855.6 OAJ22650.1 - 1.5e-13 50.3 0.3 2.3e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ22650.1 - 1.6e-09 37.9 0.1 9.8e-05 22.7 0.0 3.1 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Perilipin PF03036.16 OAJ22650.1 - 0.016 14.2 0.6 0.47 9.4 0.0 2.4 2 0 0 2 2 2 0 Perilipin family LRR_1 PF00560.33 OAJ22650.1 - 0.087 13.4 0.8 96 4.2 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat Cadherin_2 PF08266.12 OAJ22652.1 - 0.0041 16.9 1.8 2.6 7.9 0.1 4.0 3 0 0 3 3 3 1 Cadherin-like Granulin PF00396.18 OAJ22652.1 - 1.2 9.5 4.9 5.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Granulin Lon_C PF05362.13 OAJ22653.1 - 4e-66 222.5 0.2 9e-66 221.3 0.2 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAJ22653.1 - 6.3e-31 107.9 0.0 1.4e-30 106.7 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAJ22653.1 - 1.9e-21 76.8 0.0 7e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 OAJ22653.1 - 1.3e-06 28.3 0.0 3.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 OAJ22653.1 - 6.3e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 OAJ22653.1 - 1.8e-05 24.9 0.0 8.3e-05 22.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 OAJ22653.1 - 2.8e-05 23.2 0.0 6.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 OAJ22653.1 - 0.00068 19.9 0.3 0.065 13.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ22653.1 - 0.00095 19.6 0.0 0.0044 17.4 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 OAJ22653.1 - 0.0011 18.7 0.0 0.0036 17.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ22653.1 - 0.0033 18.0 0.7 0.0098 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ22653.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ22653.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAJ22653.1 - 0.061 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAJ22653.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ22653.1 - 0.078 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 OAJ22653.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 OAJ22653.1 - 0.1 13.1 0.7 0.37 11.3 0.1 2.3 2 0 0 2 2 1 0 ABC transporter Macoilin PF09726.9 OAJ22653.1 - 0.43 9.1 35.1 0.65 8.5 4.1 3.2 3 0 0 3 3 3 0 Macoilin family Apt1 PF10351.9 OAJ22653.1 - 3.7 6.3 33.3 0.24 10.2 3.6 3.2 3 0 0 3 3 3 0 Golgi-body localisation protein domain Nnf1 PF03980.14 OAJ22654.1 - 1.1e-05 25.8 7.2 1.1e-05 25.8 7.2 2.9 3 1 0 3 3 2 1 Nnf1 2_5_RNA_ligase2 PF13563.6 OAJ22654.1 - 0.021 14.7 2.7 0.27 11.1 1.6 2.7 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily Golgin_A5 PF09787.9 OAJ22654.1 - 0.47 9.9 22.9 0.032 13.7 10.7 2.2 2 1 0 2 2 2 0 Golgin subfamily A member 5 OTCace_N PF02729.21 OAJ22654.1 - 0.86 9.6 4.8 0.32 11.0 0.9 2.2 2 2 1 3 3 3 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Herpes_UL6 PF01763.16 OAJ22654.1 - 0.88 8.0 8.8 0.018 13.6 2.1 1.5 2 0 0 2 2 2 0 Herpesvirus UL6 like FANCI_S1-cap PF14674.6 OAJ22654.1 - 1.2 9.3 5.7 0.3 11.2 1.0 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap UPF0242 PF06785.11 OAJ22654.1 - 1.3 9.1 18.0 1.9 8.6 3.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 OAJ22654.1 - 2.7 8.9 22.2 0.67 10.9 4.3 3.0 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4094 PF13334.6 OAJ22654.1 - 2.8 8.4 8.5 0.35 11.3 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) TPR_MLP1_2 PF07926.12 OAJ22654.1 - 6.1 6.9 25.5 3 7.9 6.4 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 OAJ22654.1 - 9.3 7.0 12.6 10 6.9 2.3 2.9 3 0 0 3 3 3 0 Initiation control protein YabA CHAD PF05235.14 OAJ22655.1 - 0.18 11.8 1.7 9.7 6.1 0.2 3.1 3 0 0 3 3 3 0 CHAD domain SNase PF00565.17 OAJ22656.1 - 3e-22 79.1 1.1 3.8e-20 72.4 1.2 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue SNF2_N PF00176.23 OAJ22657.1 - 3.2e-53 180.7 0.0 5e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAJ22657.1 - 2.5e-39 135.3 0.0 5.6e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 OAJ22657.1 - 1.3e-13 51.3 0.0 3.6e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ22657.1 - 1.2e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ22657.1 - 0.0002 21.2 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAJ22657.1 - 0.00062 19.0 0.0 0.006 15.8 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 OAJ22657.1 - 0.053 13.8 0.1 19 5.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain AMMECR1 PF01871.17 OAJ22658.1 - 1.4e-46 158.1 0.0 1.8e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Ribosomal_S3_C PF00189.20 OAJ22659.1 - 7.4e-25 87.3 0.1 3.1e-24 85.3 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAJ22659.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_S9 PF00380.19 OAJ22660.1 - 9.7e-31 106.8 0.4 1.1e-30 106.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 SPX PF03105.19 OAJ22661.1 - 7.8e-69 233.4 14.8 2.1e-47 162.9 1.0 2.3 1 1 0 2 2 2 2 SPX domain zf-C3HC4_3 PF13920.6 OAJ22661.1 - 7.7e-08 32.1 7.7 7.7e-08 32.1 7.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ22661.1 - 3.6e-07 29.9 7.5 6.3e-07 29.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ22661.1 - 2.1e-06 27.8 6.8 4.1e-06 26.9 6.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ22661.1 - 4.6e-06 26.9 10.4 9.8e-06 25.8 10.4 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAJ22661.1 - 8.9e-06 25.5 8.0 1.6e-05 24.7 8.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ22661.1 - 4.8e-05 23.2 7.5 0.0001 22.1 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ22661.1 - 9.5e-05 22.2 9.0 0.00017 21.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ22661.1 - 0.00059 19.8 5.3 0.0015 18.5 5.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger RNA_pol_3_Rpc31 PF11705.8 OAJ22661.1 - 0.0024 18.1 2.2 0.0024 18.1 2.2 3.0 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 zf-RING_4 PF14570.6 OAJ22661.1 - 0.0048 16.7 2.5 0.0096 15.7 2.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 OAJ22661.1 - 0.046 14.0 6.1 0.099 13.0 6.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAJ22661.1 - 0.12 12.3 3.4 0.34 10.8 3.3 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OAJ22661.1 - 1 9.5 5.3 1.9 8.7 5.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 tRNA_int_end_N2 PF12928.7 OAJ22662.1 - 1.2e-12 47.8 0.0 3.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAJ22662.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain ERAP1_C PF11838.8 OAJ22663.1 - 8.1e-74 249.0 0.5 1.3e-73 248.3 0.5 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ22663.1 - 4.1e-68 229.2 0.0 6.1e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ22663.1 - 6.4e-45 153.6 1.5 3.7e-41 141.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Cupin_2 PF07883.11 OAJ22664.1 - 1.6e-07 30.9 0.1 3e-06 26.9 0.1 2.2 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAJ22664.1 - 9e-05 22.1 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.12 OAJ22664.1 - 0.0012 18.4 0.1 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_6 PF12852.7 OAJ22664.1 - 0.0032 17.2 0.1 0.014 15.2 0.1 2.0 1 1 0 1 1 1 1 Cupin Cupin_8 PF13621.6 OAJ22664.1 - 0.0034 17.1 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 OAJ22664.1 - 0.0056 16.6 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain Tht1 PF04163.12 OAJ22666.1 - 0.00012 21.0 2.3 0.00052 18.9 0.0 2.0 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein ImpA_N PF06812.12 OAJ22666.1 - 0.59 10.2 4.3 0.57 10.3 1.4 2.3 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system IL32 PF15225.6 OAJ22666.1 - 1 9.8 5.0 13 6.2 0.2 3.2 2 1 0 2 2 2 0 Interleukin 32 Rad10 PF03834.14 OAJ22667.1 - 6.4e-49 164.7 0.1 1e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAJ22667.1 - 1e-07 32.4 0.0 4.2e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Trypan_PARP PF05887.11 OAJ22667.1 - 1.8e-05 24.8 5.6 3.4e-05 23.8 5.6 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HHH_2 PF12826.7 OAJ22667.1 - 0.00047 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EF1_GNE PF00736.19 OAJ22667.1 - 0.087 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain Ribosomal_60s PF00428.19 OAJ22667.1 - 0.24 12.0 1.5 1.9 9.1 1.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Adeno_E1A PF02703.14 OAJ22667.1 - 0.3 10.6 7.4 0.48 10.0 7.4 1.2 1 0 0 1 1 1 0 Early E1A protein Med6 PF04934.14 OAJ22668.1 - 4.5e-40 136.5 0.0 6.3e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component RNA_pol_3_Rpc31 PF11705.8 OAJ22668.1 - 0.0053 17.0 2.7 0.25 11.6 1.7 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 OAJ22668.1 - 0.058 13.8 2.9 0.11 12.9 2.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.13 OAJ22668.1 - 0.06 13.2 1.8 0.091 12.6 1.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 OAJ22668.1 - 0.14 11.8 0.3 0.22 11.2 0.3 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 OAJ22668.1 - 5 5.1 5.9 6.4 4.7 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 OAJ22668.1 - 5.7 7.4 12.9 12 6.3 12.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CBM_21 PF03370.13 OAJ22669.1 - 4.6e-29 100.9 0.0 8.1e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAJ22669.1 - 9.7e-07 29.3 0.1 3.5e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) 2Fe-2S_thioredx PF01257.19 OAJ22670.1 - 8.3e-59 197.6 0.0 1.1e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Oxidored_q6 PF01058.22 OAJ22671.1 - 1.8e-22 79.6 0.1 3.2e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit SLS PF14611.6 OAJ22671.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator NUDE_C PF04880.13 OAJ22671.1 - 0.22 12.0 4.6 0.43 11.0 4.6 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Dickkopf_N PF04706.12 OAJ22672.1 - 0.0026 18.2 18.0 0.14 12.7 10.8 3.6 3 0 0 3 3 3 2 Dickkopf N-terminal cysteine-rich region UCR_Fe-S_N PF10399.9 OAJ22672.1 - 9.9 5.6 9.6 28 4.2 9.6 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal zf-CCCH PF00642.24 OAJ22673.1 - 2.7e-09 36.7 2.7 5.2e-09 35.8 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 OAJ22673.1 - 7.4e-08 32.1 6.1 1.3e-07 31.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ22673.1 - 3.2e-06 27.1 9.7 6.2e-06 26.1 9.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ22673.1 - 4.4e-06 26.6 9.8 7.4e-06 25.8 9.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 OAJ22673.1 - 1.6e-05 24.8 4.4 3.2e-05 23.8 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 OAJ22673.1 - 1.8e-05 24.4 9.3 3.5e-05 23.6 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ22673.1 - 2.8e-05 24.2 8.5 6e-05 23.1 8.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ22673.1 - 4.5e-05 23.7 8.0 8.5e-05 22.8 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ22673.1 - 4.5e-05 23.2 10.0 8.2e-05 22.4 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 OAJ22673.1 - 0.00032 20.8 3.2 0.00032 20.8 3.2 1.9 2 1 0 2 2 2 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 OAJ22673.1 - 0.0016 18.2 2.9 0.0032 17.2 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-Nse PF11789.8 OAJ22673.1 - 0.0098 15.7 3.8 0.017 14.9 3.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 OAJ22673.1 - 0.059 13.2 6.4 0.11 12.4 6.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_2 PF03107.16 OAJ22673.1 - 0.71 10.2 5.8 3 8.2 1.4 2.5 1 1 1 2 2 2 0 C1 domain zf-rbx1 PF12678.7 OAJ22673.1 - 1.1 9.6 5.9 3.6 7.9 5.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain DER1 PF04511.15 OAJ22674.1 - 6.8e-29 101.2 0.5 8.6e-29 100.8 0.5 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OAJ22674.1 - 3.1 7.8 5.9 2 8.4 3.9 1.7 2 0 0 2 2 2 0 Rhomboid family F_bP_aldolase PF01116.20 OAJ22675.1 - 3.6e-95 318.6 0.0 4.1e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ribosomal_S25 PF03297.15 OAJ22676.1 - 1.6e-37 127.7 2.5 2.4e-37 127.2 2.5 1.2 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 OAJ22676.1 - 0.027 14.0 0.2 0.047 13.2 0.2 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 OAJ22676.1 - 0.056 13.4 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 MarR family Nup88 PF10168.9 OAJ22677.1 - 1.3e-13 49.8 0.5 5.8e-05 21.1 0.0 4.2 4 1 1 5 5 5 3 Nuclear pore component MIF4G_like_2 PF09090.11 OAJ22677.1 - 0.2 11.1 0.2 0.46 9.9 0.2 1.5 1 0 0 1 1 1 0 MIF4G like Rx_N PF18052.1 OAJ22677.1 - 0.89 9.9 8.1 0.16 12.3 0.4 3.0 4 0 0 4 4 4 0 Rx N-terminal domain SlyX PF04102.12 OAJ22677.1 - 1.4 9.6 10.4 4.7 7.9 0.4 3.7 3 0 0 3 3 3 0 SlyX DUF4407 PF14362.6 OAJ22677.1 - 7.8 5.8 9.1 2.2 7.6 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3818 PF12825.7 OAJ22678.1 - 3.1e-49 167.8 0.0 4.5e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ22678.1 - 4.6e-24 84.9 0.0 1e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 PX-associated V-ATPase_C PF03223.15 OAJ22679.1 - 1.9e-128 429.0 6.8 2.1e-128 428.9 6.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C YscK PF06578.12 OAJ22679.1 - 0.0032 17.0 0.9 0.0044 16.6 0.1 1.6 2 0 0 2 2 2 1 YOP proteins translocation protein K (YscK) Aldedh PF00171.22 OAJ22680.1 - 9.4e-153 509.0 0.0 1.3e-152 508.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 OAJ22680.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Thx PF17070.5 OAJ22680.1 - 0.0016 18.5 0.5 0.0016 18.5 0.5 1.7 2 0 0 2 2 2 1 30S ribosomal protein Thx AA_permease PF00324.21 OAJ22681.1 - 1.3e-107 360.3 37.8 4.9e-105 351.9 37.8 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ22681.1 - 6.7e-31 107.5 37.6 4.2e-30 104.9 37.6 1.9 1 1 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 OAJ22681.1 - 0.071 12.8 0.3 24 4.7 0.0 3.3 3 0 0 3 3 3 0 Non-classical export protein 1 GCIP PF13324.6 OAJ22683.1 - 0.14 11.8 5.9 0.16 11.5 3.3 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MPM1 PF17234.2 OAJ22683.1 - 0.84 9.9 5.7 0.46 10.7 0.4 2.5 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 TRP PF06011.12 OAJ22684.1 - 1.2e-26 93.4 17.0 3.2e-21 75.6 7.2 2.6 3 0 0 3 3 3 2 Transient receptor potential (TRP) ion channel PBP1_TM PF14812.6 OAJ22684.1 - 0.34 11.3 1.6 0.95 9.9 1.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ22684.1 - 1.1 8.5 2.3 1.7 7.9 2.3 1.1 1 0 0 1 1 1 0 NOA36 protein Lig_chan PF00060.26 OAJ22684.1 - 1.9 8.3 4.0 1 9.2 0.0 2.5 3 0 0 3 3 3 0 Ligand-gated ion channel RVT_1 PF00078.27 OAJ22685.1 - 4.8e-24 85.1 0.0 9e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ22685.1 - 9.6e-21 73.7 0.0 2e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ22685.1 - 8.7e-16 58.1 0.0 1.5e-10 41.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ22685.1 - 1.5e-13 51.0 0.0 3.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ22685.1 - 4.2e-13 49.2 0.0 9.7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 OAJ22685.1 - 0.0041 17.7 0.5 0.018 15.7 0.2 2.3 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ22685.1 - 0.025 14.8 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger PGM1_C PF18105.1 OAJ22685.1 - 0.053 13.1 0.3 0.71 9.4 0.2 2.5 2 0 0 2 2 2 0 PGM1 C-terminal domain gag-asp_proteas PF13975.6 OAJ22685.1 - 0.069 13.7 0.0 0.3 11.7 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease FAD_binding_3 PF01494.19 OAJ22687.1 - 3.8e-56 190.8 1.8 4.8e-55 187.2 1.8 2.4 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAJ22687.1 - 1.4e-17 64.2 0.0 2.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAJ22687.1 - 8.7e-05 22.7 0.0 0.00028 21.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ22687.1 - 0.00028 20.6 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ22687.1 - 0.00095 18.5 0.0 0.0027 17.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ22687.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 OAJ22687.1 - 0.0021 17.2 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAJ22687.1 - 0.0047 16.2 0.1 0.01 15.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ22687.1 - 0.0048 16.2 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 OAJ22687.1 - 0.0051 15.7 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 OAJ22687.1 - 0.0054 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ22687.1 - 0.0056 15.8 0.2 0.014 14.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 OAJ22687.1 - 0.061 13.0 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 OAJ22687.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 OAJ22687.1 - 0.22 11.8 0.0 0.65 10.3 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.24 OAJ22702.1 - 2.2e-83 280.7 0.0 2.6e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ22702.1 - 6.7e-08 32.7 0.1 2.2e-07 31.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ22702.1 - 1.7e-07 31.2 2.2 9.3e-07 28.7 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ22702.1 - 4.5e-05 23.9 0.1 0.0029 18.1 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ22702.1 - 4.6e-05 22.8 0.7 0.00031 20.1 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ22702.1 - 0.00025 19.9 0.7 0.0012 17.7 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 OAJ22702.1 - 0.00046 19.6 0.1 0.0012 18.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 OAJ22702.1 - 0.0024 17.1 0.1 0.012 14.8 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 OAJ22702.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAJ22702.1 - 0.011 15.1 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 OAJ22702.1 - 0.018 14.1 0.4 0.035 13.2 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ22702.1 - 0.023 13.8 0.1 0.023 13.8 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAJ22702.1 - 0.088 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ22702.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S5 PF00333.20 OAJ22703.1 - 1.5e-17 63.3 3.2 2.5e-17 62.6 3.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ22703.1 - 2.2e-17 62.3 0.7 7e-17 60.6 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain SPX PF03105.19 OAJ22703.1 - 0.01 15.8 1.0 0.01 15.8 1.0 1.1 1 0 0 1 1 1 0 SPX domain CBP_BcsO PF17037.5 OAJ22703.1 - 0.21 11.7 15.0 0.15 12.2 13.4 1.5 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Apt1 PF10351.9 OAJ22703.1 - 0.55 9.0 5.8 0.67 8.7 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 OAJ22703.1 - 3.8 7.5 13.7 7.8 6.5 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4692 PF15763.5 OAJ22703.1 - 9 6.7 11.7 14 6.1 11.7 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Pro_isomerase PF00160.21 OAJ22704.1 - 2.7e-41 141.5 0.2 2e-40 138.7 0.2 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L14 PF00238.19 OAJ22705.1 - 1.3e-35 122.1 0.1 1.5e-35 121.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e HTH_36 PF13730.6 OAJ22706.1 - 0.17 11.9 3.6 2.2 8.3 0.6 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain SCP2 PF02036.17 OAJ22707.1 - 3.8e-09 37.0 0.0 7.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ22707.1 - 0.048 13.9 0.0 0.069 13.4 0.0 1.2 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal FDF PF09532.10 OAJ22708.1 - 3.3e-08 34.3 3.5 6.5e-08 33.4 0.0 3.0 3 0 0 3 3 3 1 FDF domain LSM14 PF12701.7 OAJ22708.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain Zn_clus PF00172.18 OAJ22709.1 - 1.8e-06 27.9 11.5 3.8e-06 26.9 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCIP PF13324.6 OAJ22709.1 - 0.25 10.9 2.3 0.4 10.2 2.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Macoilin PF09726.9 OAJ22709.1 - 0.71 8.4 10.9 1.3 7.5 10.9 1.3 1 0 0 1 1 1 0 Macoilin family Rsa3 PF14615.6 OAJ22710.1 - 7e-07 28.7 0.0 1.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Ribosome-assembly protein 3 DUF3246 PF11596.8 OAJ22711.1 - 0.52 9.7 7.9 0.68 9.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) gag_pre-integrs PF13976.6 OAJ22712.1 - 2.8e-08 33.5 0.1 6e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain Nt_Gln_amidase PF09764.9 OAJ22713.1 - 1.1e-33 116.4 0.3 3.5e-25 88.7 0.0 4.4 3 1 0 3 3 3 2 N-terminal glutamine amidase GRASP55_65 PF04495.14 OAJ22714.1 - 4.6e-59 198.7 0.0 4.8e-49 166.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAJ22714.1 - 0.00011 21.9 0.3 0.49 10.3 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Myc_N PF01056.18 OAJ22714.1 - 0.055 13.4 0.8 0.093 12.6 0.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PDZ_2 PF13180.6 OAJ22714.1 - 0.08 13.3 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Epimerase PF01370.21 OAJ22715.1 - 3.7e-12 46.2 0.0 7.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ22715.1 - 4.5e-12 46.2 0.0 1.4e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 OAJ22715.1 - 5.8e-11 42.4 0.0 7.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAJ22715.1 - 1.9e-09 37.0 0.0 4.3e-09 35.8 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ22715.1 - 8.9e-09 34.8 0.0 1.4e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 OAJ22715.1 - 1.8e-06 27.6 0.0 5.5e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 OAJ22715.1 - 1.4e-05 24.4 0.1 0.029 13.6 0.1 2.8 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 OAJ22715.1 - 0.00057 19.4 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ22715.1 - 0.0063 16.1 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ22715.1 - 0.007 16.3 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAJ22715.1 - 0.018 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Arginase PF00491.21 OAJ22716.1 - 5.6e-73 245.9 0.0 6.5e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family PrmA PF06325.13 OAJ22717.1 - 7.6e-10 38.7 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAJ22717.1 - 3.9e-07 30.7 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22717.1 - 4.9e-05 23.9 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ22717.1 - 8.2e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22717.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ22717.1 - 0.0023 17.5 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAJ22717.1 - 0.0075 17.0 0.9 0.022 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ22717.1 - 0.031 15.3 0.0 0.11 13.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ22717.1 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_9 PF08003.11 OAJ22717.1 - 0.056 12.4 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PRMT5 PF05185.16 OAJ22717.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Granulin PF00396.18 OAJ22718.1 - 0.53 10.7 42.8 4.6 7.7 5.5 4.3 1 1 1 2 2 2 0 Granulin Pkinase PF00069.25 OAJ22719.1 - 6e-54 183.2 0.0 4.7e-51 173.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22719.1 - 2e-25 89.5 0.0 3.5e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22719.1 - 6.8e-07 28.9 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ22719.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ22719.1 - 0.042 12.9 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAJ22719.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma54_activ_2 PF14532.6 OAJ22720.1 - 0.047 13.8 0.2 0.65 10.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1664 PF07889.12 OAJ22720.1 - 4.1 7.5 9.7 6.3 6.9 3.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glyco_hydro_9 PF00759.19 OAJ22721.1 - 1.7e-95 320.9 10.5 2e-95 320.7 10.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 COX6B PF02297.17 OAJ22722.1 - 2.4e-23 82.2 0.3 3e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb PQ-loop PF04193.14 OAJ22723.1 - 5.5e-24 83.7 0.8 8.6e-14 51.1 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 OAJ22723.1 - 0.57 10.2 3.7 0.62 10.1 0.8 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Zn_clus PF00172.18 OAJ22724.1 - 0.00096 19.2 11.0 0.0017 18.4 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glycos_transf_4 PF00953.21 OAJ22725.1 - 2.2e-31 109.0 6.0 2.2e-31 109.0 6.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF4133 PF13571.6 OAJ22725.1 - 0.42 11.0 0.1 0.42 11.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) Mob1_phocein PF03637.17 OAJ22726.1 - 5.1e-59 199.1 0.8 6.1e-59 198.8 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family GPI-anchored PF10342.9 OAJ22727.1 - 9.3e-12 45.5 1.6 2.1e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FSA_C PF10479.9 OAJ22727.1 - 0.37 8.9 6.4 0.43 8.7 6.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus VP4_helical PF17478.2 OAJ22727.1 - 0.45 9.9 1.5 0.62 9.4 1.5 1.2 1 0 0 1 1 1 0 Rotavirus VP4 helical domain DUF952 PF06108.12 OAJ22728.1 - 5.2e-12 45.6 0.0 6.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Herpes_UL32 PF06070.11 OAJ22729.1 - 3.2 5.4 7.5 4.1 5.0 7.5 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Rrn6 PF10214.9 OAJ22729.1 - 7.3 5.0 14.5 9.7 4.5 14.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S10 PF00450.22 OAJ22730.1 - 1.8e-87 294.5 0.0 4.1e-76 257.1 0.0 2.3 2 1 0 2 2 2 2 Serine carboxypeptidase CAP59_mtransfer PF11735.8 OAJ22731.1 - 1.7e-69 234.2 0.0 2.4e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Cnd2 PF05786.14 OAJ22731.1 - 0.067 11.8 2.0 0.093 11.4 2.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 PBP1_TM PF14812.6 OAJ22731.1 - 6.1 7.3 10.3 17 5.9 10.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 OAJ22733.1 - 4.8e-26 91.7 0.0 3e-25 89.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22733.1 - 5.2e-09 35.8 0.0 2.6e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CK_II_beta PF01214.18 OAJ22734.1 - 7.1e-77 257.3 0.0 1.5e-76 256.3 0.0 1.5 2 0 0 2 2 2 1 Casein kinase II regulatory subunit TMEM51 PF15345.6 OAJ22734.1 - 0.097 12.5 0.3 0.097 12.5 0.3 2.5 2 1 0 2 2 2 0 Transmembrane protein 51 TFIIA PF03153.13 OAJ22734.1 - 1.1 9.1 23.6 0.18 11.8 18.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 OAJ22734.1 - 2.4 7.4 15.6 4 6.7 15.6 1.3 1 0 0 1 1 1 0 BUD22 COX17 PF05051.13 OAJ22735.1 - 2.2e-20 72.8 4.9 2.9e-20 72.3 4.9 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 OAJ22735.1 - 0.059 13.6 1.2 0.081 13.2 1.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3807 PF12720.7 OAJ22736.1 - 1.1 9.5 36.2 0.23 11.7 11.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) ELL PF10390.9 OAJ22736.1 - 5.8 6.3 19.7 1.9 7.9 5.5 2.1 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL DHHC PF01529.20 OAJ22737.1 - 5.6e-39 133.3 2.9 5.6e-39 133.3 2.9 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pox_A14 PF05767.12 OAJ22737.1 - 0.12 12.6 0.5 0.32 11.2 0.5 1.7 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 AAA_23 PF13476.6 OAJ22738.1 - 2.2e-19 70.8 47.0 2.2e-19 70.8 47.0 8.0 1 1 3 4 4 2 1 AAA domain AAA_21 PF13304.6 OAJ22738.1 - 4.3e-13 49.7 0.3 1.1e-05 25.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ22738.1 - 2.3e-09 37.0 0.1 2.3e-09 37.0 0.1 2.9 3 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 OAJ22738.1 - 4.2e-08 33.3 54.6 0.00016 21.5 22.4 5.0 1 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 OAJ22738.1 - 9.8e-06 25.7 0.0 5.4e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OAJ22738.1 - 4.9e-05 23.0 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6_N PF17675.1 OAJ22738.1 - 0.0017 18.9 8.2 0.0017 18.9 8.2 8.9 2 2 6 8 8 7 1 Apg6 coiled-coil region ABC_tran PF00005.27 OAJ22738.1 - 0.002 18.6 0.3 0.002 18.6 0.3 6.6 2 2 1 4 4 3 1 ABC transporter TMF_TATA_bd PF12325.8 OAJ22738.1 - 0.0086 16.3 12.3 0.0086 16.3 12.3 9.8 4 3 4 9 9 8 1 TATA element modulatory factor 1 TATA binding Roc PF08477.13 OAJ22738.1 - 0.027 14.7 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Flavi_capsid PF01003.19 OAJ22738.1 - 0.028 14.2 0.1 0.11 12.3 0.1 2.0 1 0 0 1 1 1 0 Flavivirus capsid protein C AAA_22 PF13401.6 OAJ22738.1 - 0.086 13.1 0.5 1 9.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ22738.1 - 0.42 11.0 0.0 0.42 11.0 0.0 4.9 4 2 0 5 5 4 0 AAA ATPase domain CBFB_NFYA PF02045.15 OAJ22739.1 - 6e-18 65.2 20.8 1.4e-11 44.8 3.9 2.9 3 0 0 3 3 3 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B TFIIA PF03153.13 OAJ22739.1 - 0.8 9.6 33.9 0.056 13.4 19.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_S10 PF00450.22 OAJ22740.1 - 6e-101 338.9 0.0 7.6e-101 338.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase NADHdh_A3 PF14987.6 OAJ22742.1 - 0.13 12.6 0.0 0.16 12.3 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 UPF0014 PF03649.13 OAJ22742.1 - 0.2 10.9 0.1 0.23 10.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) RRM_1 PF00076.22 OAJ22743.1 - 7e-34 115.5 0.0 9.4e-14 51.0 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ22743.1 - 0.0012 19.0 0.0 1.3 9.2 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ22743.1 - 0.0017 18.3 0.0 2.4 8.2 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 OAJ22743.1 - 0.01 15.8 0.0 0.042 13.8 0.0 2.2 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAJ22743.1 - 0.034 13.7 0.0 0.37 10.4 0.0 2.7 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 OAJ22743.1 - 0.038 14.0 0.0 0.2 11.7 0.0 2.2 1 0 0 1 1 1 0 RNA binding domain Ribosomal_S16 PF00886.19 OAJ22744.1 - 8.5e-25 86.6 0.2 2.4e-24 85.2 0.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S16 NADH_B2 PF14813.6 OAJ22745.1 - 0.00017 21.3 0.4 0.00022 21.0 0.4 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Mit_KHE1 PF10173.9 OAJ22746.1 - 2.6e-54 184.2 0.1 3.7e-54 183.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Herpes_pp85 PF04637.12 OAJ22746.1 - 5 5.4 7.1 7.1 4.9 7.1 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) VWA PF00092.28 OAJ22747.1 - 7.7e-10 39.3 0.0 2.4e-09 37.7 0.0 1.8 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAJ22747.1 - 7.2e-09 36.3 0.0 1.7e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.8 OAJ22747.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.18 OAJ22747.1 - 0.037 13.7 0.0 1.5 8.4 0.0 2.2 1 1 1 2 2 2 0 Integrin beta chain VWA domain TssR PF17643.1 OAJ22747.1 - 0.13 10.2 0.0 0.18 9.7 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssR ATP_bind_1 PF03029.17 OAJ22748.1 - 2.2e-69 233.9 0.1 3.4e-64 216.9 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 OAJ22748.1 - 0.00014 21.9 0.0 0.00095 19.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 OAJ22748.1 - 0.00053 19.7 1.9 0.0037 16.9 1.3 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAJ22748.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAJ22748.1 - 0.0049 16.6 0.1 0.0097 15.7 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 OAJ22748.1 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 OAJ22748.1 - 0.0076 16.2 0.1 0.062 13.2 0.1 2.1 2 0 0 2 2 2 1 NTPase RsgA_GTPase PF03193.16 OAJ22748.1 - 0.0081 16.1 0.1 1.5 8.7 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase MeaB PF03308.16 OAJ22748.1 - 0.011 14.8 0.7 0.66 8.9 0.5 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 OAJ22748.1 - 0.012 15.3 0.7 0.15 11.7 0.7 2.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ22748.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 OAJ22748.1 - 0.014 15.9 0.1 0.014 15.9 0.1 2.2 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 OAJ22748.1 - 0.016 15.6 2.1 0.017 15.5 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 OAJ22748.1 - 0.017 15.6 0.1 0.017 15.6 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 OAJ22748.1 - 0.018 15.3 0.1 0.018 15.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ22748.1 - 0.022 15.0 0.2 0.063 13.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAJ22748.1 - 0.024 14.2 0.5 0.071 12.7 0.5 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAJ22748.1 - 0.057 13.0 0.1 14 5.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 OAJ22748.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAJ22748.1 - 0.092 12.5 4.7 0.23 11.2 4.7 1.6 1 0 0 1 1 1 0 AAA domain CobU PF02283.16 OAJ22748.1 - 0.14 11.7 1.1 0.38 10.3 1.1 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase FtsK_SpoIIIE PF01580.18 OAJ22748.1 - 0.15 11.4 0.7 0.51 9.6 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRPRB PF09439.10 OAJ22748.1 - 0.2 11.1 0.0 0.9 8.9 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 OAJ22748.1 - 0.37 10.5 1.3 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase DUF87 PF01935.17 OAJ22748.1 - 0.4 10.7 2.9 0.7 9.9 1.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Histone_H2A_C PF16211.5 OAJ22749.1 - 5.7e-14 51.6 0.3 8.8e-14 51.0 0.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ22749.1 - 3e-12 47.0 0.0 5.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ22749.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4504 PF14953.6 OAJ22750.1 - 3.8e-10 39.6 0.0 1.2e-07 31.4 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) Thiolase_N PF00108.23 OAJ22751.1 - 7.8e-66 222.1 0.1 1e-65 221.7 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ22751.1 - 2.4e-40 137.0 0.3 4.5e-40 136.1 0.3 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 OAJ22751.1 - 0.0012 18.7 0.7 0.093 12.6 0.0 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 OAJ22751.1 - 0.012 15.2 2.2 0.11 12.1 1.1 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 OAJ22751.1 - 0.019 15.1 0.1 0.05 13.8 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal UPF0167 PF03691.14 OAJ22752.1 - 0.022 14.5 0.2 7.5 6.3 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0167) RVT_2 PF07727.14 OAJ22758.1 - 1.9e-19 70.3 0.0 2.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAJ22758.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ22758.1 - 0.23 11.3 0.9 0.52 10.1 0.9 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like RVT_2 PF07727.14 OAJ22759.1 - 2.1e-34 119.3 0.0 2.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ResB PF05140.14 OAJ22759.1 - 0.23 10.1 1.8 0.36 9.5 1.8 1.2 1 0 0 1 1 1 0 ResB-like family LsmAD PF06741.13 OAJ22759.1 - 0.85 10.2 4.1 2.2 8.9 4.1 1.6 1 0 0 1 1 1 0 LsmAD domain BAF1_ABF1 PF04684.13 OAJ22759.1 - 0.95 8.4 4.9 1.4 7.9 4.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SKA2 PF16740.5 OAJ22759.1 - 1.3 8.9 6.3 2.1 8.2 6.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 FlgN PF05130.12 OAJ22760.1 - 0.0069 16.9 1.4 0.012 16.1 1.4 1.4 1 0 0 1 1 1 1 FlgN protein Macoilin PF09726.9 OAJ22760.1 - 0.037 12.6 1.6 0.061 11.9 1.7 1.4 1 1 0 1 1 1 0 Macoilin family FAM76 PF16046.5 OAJ22760.1 - 0.039 13.3 0.3 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 FAM76 protein Peptidase_C7 PF01830.18 OAJ22760.1 - 0.058 12.8 0.1 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase C7 family She9_MDM33 PF05546.11 OAJ22760.1 - 0.076 12.8 1.0 0.13 12.0 1.0 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family TMF_TATA_bd PF12325.8 OAJ22760.1 - 0.12 12.6 2.7 0.18 12.0 2.1 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 OAJ22760.1 - 0.16 10.8 5.2 0.23 10.3 5.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tho2 PF11262.8 OAJ22760.1 - 0.27 10.4 1.7 0.41 9.8 1.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 GPS2_interact PF15784.5 OAJ22760.1 - 0.5 10.8 5.9 0.19 12.2 3.0 1.8 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Abhydrolase_1 PF00561.20 OAJ22762.1 - 1.7e-08 34.5 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ22762.1 - 2.4e-08 34.8 0.4 4e-08 34.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ22762.1 - 2.8e-05 23.5 0.0 6.4e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cullin PF00888.22 OAJ22763.1 - 5e-177 590.3 3.2 7.3e-177 589.7 3.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ22763.1 - 4.8e-27 93.8 1.6 1e-26 92.7 1.6 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_IclR PF09339.10 OAJ22763.1 - 0.014 15.1 0.3 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_20 PF12840.7 OAJ22763.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Penicillinase_R PF03965.16 OAJ22763.1 - 0.091 13.1 2.4 14 6.0 0.1 3.9 4 0 0 4 4 4 0 Penicillinase repressor MarR_2 PF12802.7 OAJ22763.1 - 0.14 12.1 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 MarR family DUF4404 PF14357.6 OAJ22763.1 - 0.18 12.5 1.2 9.2 7.0 0.2 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ubie_methyltran PF01209.18 OAJ22764.1 - 6.1e-71 238.5 0.0 3.9e-68 229.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAJ22764.1 - 5.6e-12 46.2 0.0 3.6e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ22764.1 - 2.6e-11 44.0 0.0 4e-09 37.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ22764.1 - 8.3e-11 42.5 0.0 1.5e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ22764.1 - 2.2e-06 27.6 0.0 1.3e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ22764.1 - 2.1e-05 24.4 0.0 5e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAJ22764.1 - 0.019 14.8 0.0 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Glyco_transf_90 PF05686.12 OAJ22764.1 - 0.12 11.2 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Fasciclin PF02469.22 OAJ22765.1 - 6e-29 100.9 8.4 2.4e-21 76.3 2.6 2.3 2 0 0 2 2 2 2 Fasciclin domain DnaJ PF00226.31 OAJ22766.1 - 1.2e-09 38.2 0.1 5e-08 33.0 0.0 3.1 3 0 0 3 3 3 1 DnaJ domain DUF2368 PF10166.9 OAJ22768.1 - 3.7 7.2 5.9 8.3 6.0 5.9 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Metallophos PF00149.28 OAJ22769.1 - 1.1e-37 130.6 0.3 1.5e-37 130.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ22769.1 - 0.058 13.8 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ22769.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain HA2 PF04408.23 OAJ22770.1 - 8.5e-21 74.3 2.1 2e-20 73.1 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ22770.1 - 1.9e-18 66.6 0.0 5.3e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ22770.1 - 2.7e-15 56.6 0.0 6.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ22770.1 - 1.4e-07 31.5 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ22770.1 - 0.00013 21.7 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ22770.1 - 0.00045 20.5 0.0 0.002 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ22770.1 - 0.00093 19.6 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAJ22770.1 - 0.005 16.5 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PWI PF01480.17 OAJ22770.1 - 0.0061 16.8 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 PWI domain T2SSE PF00437.20 OAJ22770.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ22770.1 - 0.037 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 OAJ22770.1 - 0.083 12.9 1.4 3.1 7.8 0.1 3.5 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 OAJ22770.1 - 0.14 12.2 0.2 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAJ22770.1 - 0.39 11.2 2.5 0.53 10.8 0.0 2.5 3 0 0 3 3 3 0 ABC transporter TPR_MLP1_2 PF07926.12 OAJ22772.1 - 2.9e-26 92.0 18.8 2.9e-26 92.0 18.8 19.2 8 4 10 18 18 18 6 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAJ22772.1 - 0.0032 17.6 16.8 0.0032 17.6 16.8 18.8 9 4 10 19 19 19 4 Afadin- and alpha -actinin-Binding COG2 PF06148.11 OAJ22772.1 - 0.021 14.9 0.4 0.021 14.9 0.4 16.7 10 5 8 20 20 20 0 COG (conserved oligomeric Golgi) complex component, COG2 F-actin_cap_A PF01267.17 OAJ22774.1 - 1.9e-70 237.3 0.0 2.4e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Hid1 PF12722.7 OAJ22774.1 - 0.73 7.9 1.9 1.1 7.3 1.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_C48 PF02902.19 OAJ22775.1 - 3.6e-25 89.1 0.0 1.9e-14 54.0 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain TPR_2 PF07719.17 OAJ22775.1 - 3.4e-05 23.6 2.2 1.7 8.9 0.8 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat Ras PF00071.22 OAJ22776.1 - 9.2e-51 171.7 0.3 1.1e-50 171.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ22776.1 - 7.2e-31 106.9 0.1 9.4e-31 106.5 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ22776.1 - 9.7e-16 57.7 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ22776.1 - 3.7e-05 23.8 0.0 0.00015 21.8 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ22776.1 - 0.00042 19.7 0.0 0.00052 19.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAJ22776.1 - 0.0018 17.7 0.1 0.0024 17.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAJ22776.1 - 0.0073 15.9 0.4 0.029 13.9 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OAJ22776.1 - 0.085 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 OAJ22776.1 - 0.14 11.9 0.1 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UCH PF00443.29 OAJ22777.1 - 1.3e-36 126.5 0.0 2.2e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ22777.1 - 1.4e-06 28.1 0.0 0.00019 21.1 0.0 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HapK PF11639.8 OAJ22779.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.5 1 0 0 1 1 1 0 REDY-like protein HapK CM_2 PF01817.21 OAJ22780.1 - 0.0018 18.6 0.1 0.3 11.5 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II CBFD_NFYB_HMF PF00808.23 OAJ22781.1 - 4.1e-14 52.6 0.0 7.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ22781.1 - 0.0043 17.4 0.9 0.0076 16.6 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 OAJ22781.1 - 0.1 12.7 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Serglycin PF04360.12 OAJ22781.1 - 0.14 12.1 6.0 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Serglycin PBP1_TM PF14812.6 OAJ22781.1 - 0.31 11.5 13.2 0.15 12.5 1.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ22781.1 - 6.5 7.2 13.9 10 6.6 8.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain 5-FTHF_cyc-lig PF01812.20 OAJ22782.1 - 2.2e-30 105.9 0.1 9e-29 100.6 0.1 2.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2967 PF11179.8 OAJ22782.1 - 1.5 6.8 8.3 1.8 6.5 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) FAD_binding_4 PF01565.23 OAJ22784.1 - 5.3e-21 74.8 2.5 5.3e-21 74.8 2.5 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ22784.1 - 0.0068 16.5 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like CMS1 PF14617.6 OAJ22785.1 - 3.9e-16 59.1 12.6 2.2e-13 50.1 0.0 4.4 2 2 1 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.16 OAJ22809.1 - 6e-35 120.8 34.4 4.5e-33 114.6 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ22809.1 - 3e-13 49.4 14.2 9.2e-13 47.9 13.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ22809.1 - 1.4e-05 23.7 5.4 4.5e-05 22.1 3.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cytomega_TRL10 PF06084.11 OAJ22809.1 - 0.27 11.3 0.9 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein UL42 PF17638.2 OAJ22809.1 - 0.38 10.7 2.5 0.45 10.5 0.1 2.4 3 0 0 3 3 3 0 HCMV UL42 DUF2040 PF09745.9 OAJ22810.1 - 5.8e-32 110.3 17.0 5.8e-32 110.3 17.0 2.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Lyase_aromatic PF00221.19 OAJ22811.1 - 1.9e-120 402.7 3.9 3.4e-120 401.8 3.9 1.4 1 1 0 1 1 1 1 Aromatic amino acid lyase Nitroreductase PF00881.24 OAJ22811.1 - 0.084 12.9 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Nitroreductase family Transp_cyt_pur PF02133.15 OAJ22812.1 - 9.2e-17 60.9 28.5 1.3e-16 60.5 28.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HAT_KAT11 PF08214.11 OAJ22813.1 - 6e-27 94.8 0.4 1.1e-14 54.5 0.0 4.2 3 2 0 3 3 3 2 Histone acetylation protein zf-PARP PF00645.18 OAJ22813.1 - 6.6e-22 78.2 0.0 1.6e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BUD22 PF09073.10 OAJ22813.1 - 0.48 9.7 36.1 1.1 8.5 36.1 1.5 1 0 0 1 1 1 0 BUD22 Sec2p PF06428.11 OAJ22814.1 - 2.4e-17 62.7 9.4 2.4e-17 62.7 9.4 1.8 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF21 PF01595.20 OAJ22815.1 - 3e-38 131.3 0.6 6.9e-38 130.1 0.2 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ22815.1 - 0.019 15.4 0.4 1.9 9.0 0.0 3.4 3 0 0 3 3 3 0 CBS domain RHD3 PF05879.12 OAJ22816.1 - 5e-247 821.8 0.0 6.2e-247 821.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OAJ22816.1 - 2.4e-05 24.4 0.0 6.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ22816.1 - 5.3e-05 23.3 0.2 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GBP PF02263.19 OAJ22816.1 - 5.5e-05 22.6 0.2 0.0001 21.7 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 OAJ22816.1 - 0.017 15.3 1.4 0.026 14.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ22816.1 - 0.16 12.3 2.6 1.3 9.4 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_M13_N PF05649.13 OAJ22817.1 - 3e-84 283.9 0.0 3.9e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAJ22817.1 - 1.6e-57 194.4 0.0 2.8e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF3381 PF11861.8 OAJ22817.1 - 0.12 12.2 0.5 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PikAIV_N PF18605.1 OAJ22817.1 - 0.18 11.4 0.3 0.35 10.5 0.3 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain AAA PF00004.29 OAJ22818.1 - 4.6e-84 279.5 0.0 1.9e-41 141.6 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ22818.1 - 2.3e-25 88.1 4.3 2.9e-12 46.2 0.7 2.9 3 0 0 3 3 2 2 AAA+ lid domain AAA_5 PF07728.14 OAJ22818.1 - 2.8e-15 56.5 0.0 3.8e-06 26.9 0.0 4.6 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ22818.1 - 2.4e-13 50.1 0.0 4.7e-06 26.4 0.0 3.1 4 0 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ22818.1 - 3.5e-13 50.3 2.2 6e-07 30.0 0.3 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ22818.1 - 3.7e-09 37.0 0.5 0.0016 18.7 0.1 4.3 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 OAJ22818.1 - 1e-07 31.5 0.0 0.00054 19.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 OAJ22818.1 - 5.5e-07 29.4 1.9 0.065 12.8 0.1 4.0 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 OAJ22818.1 - 1.4e-06 28.5 0.0 0.013 15.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAJ22818.1 - 3.1e-06 27.4 0.0 0.15 12.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAJ22818.1 - 4.5e-06 26.7 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ22818.1 - 7.3e-06 25.8 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OAJ22818.1 - 9.9e-06 25.6 0.1 0.063 13.2 0.0 3.5 2 1 1 3 3 3 1 Rad17 P-loop domain Mg_chelatase PF01078.21 OAJ22818.1 - 1.2e-05 24.8 0.3 0.095 12.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAJ22818.1 - 3.3e-05 24.4 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ22818.1 - 3.6e-05 24.1 0.0 0.39 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 OAJ22818.1 - 0.00014 22.1 0.0 0.18 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAJ22818.1 - 0.00019 21.0 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ22818.1 - 0.00019 21.2 0.0 0.01 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ22818.1 - 0.00092 18.5 0.0 0.058 12.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 OAJ22818.1 - 0.0019 18.2 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAJ22818.1 - 0.003 17.5 0.1 3.4 7.6 0.0 3.2 2 1 0 2 2 2 1 NACHT domain AAA_3 PF07726.11 OAJ22818.1 - 0.0037 17.1 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAJ22818.1 - 0.0046 16.3 0.0 2 7.7 0.0 2.8 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 OAJ22818.1 - 0.0047 17.4 0.6 0.87 10.1 0.0 3.8 5 0 0 5 5 3 1 ABC transporter AAA_17 PF13207.6 OAJ22818.1 - 0.0052 17.2 0.0 4.1 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 OAJ22818.1 - 0.0086 16.2 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 OAJ22818.1 - 0.013 15.2 0.0 7.5 6.2 0.0 3.5 2 1 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OAJ22818.1 - 0.016 15.1 0.4 1.3 8.9 0.0 3.5 2 2 1 4 4 4 0 NTPase AAA_11 PF13086.6 OAJ22818.1 - 0.021 14.7 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ22818.1 - 0.026 14.0 0.1 0.78 9.1 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 OAJ22818.1 - 0.027 13.6 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 OAJ22818.1 - 0.044 13.5 0.0 0.66 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAJ22818.1 - 0.063 13.6 0.8 0.98 9.8 0.2 2.8 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAJ22818.1 - 0.15 11.8 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TFIIA_gamma_N PF02268.16 OAJ22819.1 - 1.9e-24 85.4 0.1 2.6e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 OAJ22819.1 - 1.6e-19 69.8 0.2 2.2e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit NCBP3 PF10309.9 OAJ22820.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OAJ22820.1 - 0.0072 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain SOG2 PF10428.9 OAJ22820.1 - 2 7.5 7.5 2.1 7.5 7.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_zinc_N PF00107.26 OAJ22821.1 - 2.8e-25 88.8 0.3 8e-25 87.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ22821.1 - 1e-15 58.9 0.0 2.7e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ22821.1 - 2.8e-08 33.6 0.0 1.1e-06 28.5 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ22821.1 - 0.00024 21.0 0.2 0.0012 18.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase PA PF02225.22 OAJ22821.1 - 0.13 12.3 1.5 0.66 10.0 0.6 2.4 2 1 0 2 2 2 0 PA domain Mito_carr PF00153.27 OAJ22822.1 - 1.8e-45 152.8 4.9 3.6e-16 58.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 OAJ22824.1 - 3.6e-56 190.5 0.0 4.6e-34 118.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22824.1 - 2.8e-23 82.6 0.1 1.5e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ22824.1 - 0.024 13.6 0.1 0.039 12.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ22824.1 - 0.041 13.8 0.4 0.041 13.8 0.4 3.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_C PF00433.24 OAJ22824.1 - 0.061 14.0 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain HEAT_PBS PF03130.16 OAJ22824.1 - 0.063 14.0 0.0 0.23 12.2 0.0 2.0 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat Kinase-like PF14531.6 OAJ22824.1 - 0.066 12.5 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.6 OAJ22825.1 - 9.2e-61 205.9 40.1 1.2e-60 205.6 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ22825.1 - 3.2e-27 95.3 35.1 4.4e-27 94.8 35.1 1.2 1 0 0 1 1 1 1 Amino acid permease HlyIII PF03006.20 OAJ22826.1 - 2.3e-48 164.8 21.5 3e-48 164.5 21.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related PGG PF13962.6 OAJ22826.1 - 0.19 11.6 3.4 0.55 10.1 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function ADH_N PF08240.12 OAJ22827.1 - 7.8e-09 35.4 0.0 2.5e-07 30.6 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ22827.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase PUF PF00806.19 OAJ22828.1 - 7.7e-59 192.2 2.6 3e-08 32.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF4049 PF13258.6 OAJ22828.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) Fer2_3 PF13085.6 OAJ22829.1 - 2.3e-32 111.3 0.0 3.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAJ22829.1 - 5.2e-09 36.5 6.1 5.2e-09 36.5 6.1 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ22829.1 - 4.9e-07 30.1 7.3 4.9e-07 30.1 7.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAJ22829.1 - 8.5e-07 29.0 3.6 8.5e-07 29.0 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAJ22829.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OAJ22829.1 - 0.018 15.6 6.5 0.018 15.6 6.5 2.6 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OAJ22829.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAJ22829.1 - 2.3 8.4 14.6 0.4 10.9 8.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Tetraspanin PF00335.20 OAJ22830.1 - 7.3e-14 52.0 4.7 1e-13 51.5 4.7 1.1 1 0 0 1 1 1 1 Tetraspanin family YL1_C PF08265.11 OAJ22831.1 - 7.4e-13 48.0 0.5 1.2e-12 47.3 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain M_domain PF12938.7 OAJ22831.1 - 0.11 12.2 1.7 0.16 11.8 1.7 1.1 1 0 0 1 1 1 0 M domain of GW182 RRM_1 PF00076.22 OAJ22832.1 - 2e-10 40.3 0.0 5.6e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 OAJ22832.1 - 0.0066 17.0 4.8 0.011 16.3 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) Ins_P5_2-kin PF06090.12 OAJ22833.1 - 2.3e-65 221.3 0.0 2.9e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.26 OAJ22833.1 - 1.1e-11 44.4 7.3 2.3e-05 24.6 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ22833.1 - 8.6e-06 26.2 6.3 0.031 15.1 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ22833.1 - 0.014 15.8 0.6 0.014 15.8 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 OAJ22833.1 - 0.044 13.5 1.8 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF3268 PF11672.8 OAJ22833.1 - 0.17 12.2 0.6 0.35 11.2 0.6 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_6 PF13912.6 OAJ22833.1 - 2.4 8.2 4.6 7.6 6.7 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAJ22833.1 - 4.7 7.7 10.5 0.39 11.2 1.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 OAJ22833.1 - 7.5 7.0 6.9 6.9 7.1 1.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PhyH PF05721.13 OAJ22835.1 - 1.7e-43 149.3 0.0 2.8e-43 148.6 0.0 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 OAJ22835.1 - 0.019 15.3 0.0 0.22 12.0 0.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase RRP7 PF12923.7 OAJ22836.1 - 2.8e-22 79.1 0.3 2.8e-22 79.1 0.3 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAJ22836.1 - 5.5e-15 55.5 0.1 4.5e-14 52.6 0.1 2.1 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 OAJ22836.1 - 0.0035 17.1 0.0 0.0094 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 OAJ22836.1 - 0.089 11.1 0.7 0.13 10.5 0.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L4 PF00573.22 OAJ22839.1 - 5.9e-40 137.0 0.3 1.2e-39 136.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAJ22839.1 - 5.2e-28 96.9 0.3 2.8e-27 94.6 0.2 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain WD40 PF00400.32 OAJ22841.1 - 7.2e-09 36.2 0.7 0.014 16.2 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat BUD22 PF09073.10 OAJ22841.1 - 0.027 13.8 2.6 0.043 13.2 2.6 1.3 1 0 0 1 1 1 0 BUD22 ANAPC4_WD40 PF12894.7 OAJ22841.1 - 0.2 12.0 0.0 55 4.2 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain REV PF00424.18 OAJ22841.1 - 1.5 8.9 4.0 17 5.5 0.2 2.9 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RPN1_RPN2_N PF17781.1 OAJ22842.1 - 2.2e-113 378.8 0.0 4.9e-113 377.6 0.0 1.6 1 1 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAJ22842.1 - 1.8e-28 98.3 0.5 4.2e-28 97.2 0.1 1.9 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAJ22842.1 - 8.8e-17 60.6 25.7 0.001 19.4 0.0 9.2 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 OAJ22842.1 - 0.0019 18.6 1.2 1.1 9.7 0.1 4.2 3 0 0 3 3 3 1 HEAT repeats Pyr_redox_2 PF07992.14 OAJ22843.1 - 9.5e-51 172.8 0.1 1.1e-50 172.5 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ22843.1 - 8.2e-18 64.7 0.1 6.2e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ22843.1 - 5e-17 62.1 0.2 3.3e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ22843.1 - 4.4e-06 26.3 0.0 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ22843.1 - 1.1e-05 24.8 0.3 0.00013 21.3 0.0 2.4 2 1 1 3 3 3 1 Thi4 family GIDA PF01134.22 OAJ22843.1 - 0.00014 21.1 1.5 0.0062 15.7 0.1 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ22843.1 - 0.00017 21.0 0.1 0.023 13.9 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 OAJ22843.1 - 0.00023 20.4 1.3 0.0059 15.7 0.5 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ22843.1 - 0.00072 19.7 0.4 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OAJ22843.1 - 0.0027 18.1 0.1 0.11 13.0 0.0 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 OAJ22843.1 - 0.0048 15.8 0.1 0.061 12.2 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.24 OAJ22843.1 - 0.0066 16.1 0.8 0.027 14.1 0.6 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ22843.1 - 0.0081 14.9 0.1 0.032 13.0 0.1 2.0 1 1 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 OAJ22843.1 - 0.013 14.6 0.0 0.39 9.8 0.0 2.7 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 OAJ22843.1 - 0.028 14.5 0.0 9.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Nfu_N PF08712.11 OAJ22844.1 - 7.2e-33 112.5 0.0 2.6e-32 110.7 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAJ22844.1 - 2.1e-24 85.5 0.1 4.1e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain zf-Tim10_DDP PF02953.15 OAJ22845.1 - 1.8e-21 75.5 2.3 2.2e-21 75.3 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.6 OAJ22845.1 - 0.016 14.9 0.6 0.02 14.6 0.6 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 Herpes_UL42 PF02282.16 OAJ22845.1 - 0.034 14.0 0.2 0.047 13.6 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) DUF842 PF05811.13 OAJ22845.1 - 0.05 13.3 4.0 1.5 8.5 0.9 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3398 PF11878.8 OAJ22845.1 - 0.093 13.2 0.3 0.13 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Aminotran_1_2 PF00155.21 OAJ22846.1 - 2.5e-56 191.4 0.0 3.2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cyt-b5 PF00173.28 OAJ22847.1 - 4.6e-23 81.2 0.3 5.1e-23 81.0 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 OAJ22847.1 - 0.1 12.7 0.0 0.35 11.0 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H La PF05383.17 OAJ22848.1 - 8.5e-15 54.6 0.1 3.1e-14 52.8 0.1 1.9 1 1 0 1 1 1 1 La domain RRM_1 PF00076.22 OAJ22848.1 - 3.2e-05 23.7 0.0 9.3e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ22848.1 - 0.024 14.7 0.1 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif HTH_32 PF13565.6 OAJ22848.1 - 0.21 12.2 2.6 0.23 12.1 0.0 2.4 3 0 0 3 3 3 0 Homeodomain-like domain Semialdhyde_dhC PF02774.18 OAJ22849.1 - 1.7e-42 145.5 0.0 3.5e-42 144.6 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAJ22849.1 - 6.8e-29 100.8 0.0 1.5e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAJ22849.1 - 0.01 15.9 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 OAJ22849.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GATA PF00320.27 OAJ22850.1 - 8.1e-17 60.5 5.1 1.6e-16 59.6 5.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAJ22850.1 - 1.2e-13 50.6 1.2 2.3e-13 49.7 1.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SNARE PF05739.19 OAJ22852.1 - 9.1e-11 41.6 0.1 2.4e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 OAJ22852.1 - 1e-10 41.8 1.9 1e-10 41.8 1.9 2.5 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 OAJ22852.1 - 0.00052 19.7 9.4 0.00058 19.6 1.3 2.3 2 0 0 2 2 2 2 Syntaxin Caskin1-CID PF16600.5 OAJ22852.1 - 0.055 14.0 3.5 0.15 12.7 3.5 1.7 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DUF2730 PF10805.8 OAJ22852.1 - 0.1 12.7 0.6 0.46 10.6 0.1 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) Arrestin_C PF02752.22 OAJ22853.1 - 0.00013 22.5 0.0 0.00039 20.9 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ22853.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF1154 PF06631.11 OAJ22854.1 - 0.0044 17.0 0.0 0.024 14.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) DnaJ PF00226.31 OAJ22855.1 - 2.3e-18 66.1 0.1 6.3e-18 64.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 OAJ22855.1 - 1.3e-13 51.7 5.6 1.3e-13 51.7 5.6 3.2 3 0 0 3 3 3 1 Ribosome-associated complex head domain AAA_23 PF13476.6 OAJ22855.1 - 1.3 9.5 11.6 0.22 12.0 7.2 2.0 3 0 0 3 3 3 0 AAA domain Hid1 PF12722.7 OAJ22855.1 - 3.7 5.5 4.9 5.3 5.0 4.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U1snRNP70_N PF12220.8 OAJ22855.1 - 4.2 8.1 17.8 2.7 8.7 0.2 4.1 4 0 0 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Presenilin PF01080.17 OAJ22855.1 - 4.2 6.0 7.2 7 5.3 7.2 1.3 1 0 0 1 1 1 0 Presenilin Wbp11 PF09429.10 OAJ22856.1 - 10 6.6 9.1 22 5.5 3.8 2.9 2 1 1 3 3 3 0 WW domain binding protein 11 Rad52_Rad22 PF04098.15 OAJ22857.1 - 1.2e-55 187.6 0.0 1.9e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 OAJ22857.1 - 6 6.7 12.6 12 5.8 12.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TBCA PF02970.16 OAJ22858.1 - 2.4e-27 95.1 4.9 2.4e-27 95.1 4.9 1.6 1 1 1 2 2 2 1 Tubulin binding cofactor A Phage_Gp23 PF10669.9 OAJ22858.1 - 0.1 12.9 5.4 0.1 12.9 5.0 1.3 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cytochrom_C_2 PF01322.20 OAJ22858.1 - 0.13 13.2 5.2 0.31 11.9 5.2 1.6 1 1 0 1 1 1 0 Cytochrome C' Atg14 PF10186.9 OAJ22858.1 - 8 5.5 9.4 8.6 5.3 9.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLTH PF10607.9 OAJ22859.1 - 4e-12 46.3 0.0 9.7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAJ22859.1 - 2.3e-08 33.9 0.2 5e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ22859.1 - 5.9e-05 22.9 0.6 0.00012 21.9 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ22859.1 - 0.00077 19.6 0.4 0.0017 18.4 0.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAJ22859.1 - 0.0016 18.3 0.6 0.0035 17.2 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ22859.1 - 0.0021 17.9 0.8 0.0043 16.9 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ22859.1 - 0.0023 17.7 1.4 0.0045 16.8 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ22859.1 - 0.0049 17.2 1.3 0.011 16.0 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain COG6 PF06419.11 OAJ22859.1 - 0.0093 14.2 0.7 0.013 13.7 0.7 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Prok-RING_4 PF14447.6 OAJ22859.1 - 0.0098 15.7 1.7 0.02 14.7 1.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 LisH PF08513.11 OAJ22859.1 - 0.026 14.5 0.0 0.092 12.7 0.0 2.0 2 0 0 2 2 2 0 LisH LMP PF04778.12 OAJ22859.1 - 0.4 10.6 2.5 2.5 8.0 1.1 2.2 2 0 0 2 2 2 0 LMP repeated region DUF1664 PF07889.12 OAJ22859.1 - 0.49 10.4 2.0 26 4.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SH2_2 PF14633.6 OAJ22862.1 - 3.1e-75 252.3 0.0 3.1e-75 252.3 0.0 2.3 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 OAJ22862.1 - 9.1e-23 80.6 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OAJ22862.1 - 5.1e-20 71.8 0.0 1.9e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OAJ22862.1 - 6.7e-17 61.9 28.4 6.7e-17 61.9 28.4 6.5 5 1 2 7 7 7 2 Acidic N-terminal SPT6 HTH_44 PF14641.6 OAJ22862.1 - 4.5e-10 40.0 0.0 1.3e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 OAJ22862.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 OAJ22862.1 - 0.0032 17.7 0.1 0.0074 16.5 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif CTD PF12815.7 OAJ22862.1 - 0.017 15.7 7.5 2.2 8.9 7.5 2.5 1 1 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 MA3 PF02847.17 OAJ22862.1 - 0.17 11.9 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 MA3 domain HHH_9 PF17674.1 OAJ22862.1 - 2.5 9.1 5.2 0.62 11.0 0.3 2.8 2 1 0 2 2 2 0 HHH domain CDC45 PF02724.14 OAJ22863.1 - 2.1e-204 680.5 0.0 5.1e-204 679.2 0.0 1.6 1 1 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 OAJ22863.1 - 0.046 13.1 35.4 0.28 10.5 29.7 2.1 2 0 0 2 2 2 0 BUD22 DUF4604 PF15377.6 OAJ22863.1 - 0.53 10.7 32.0 0.81 10.1 22.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) PNISR PF15996.5 OAJ22863.1 - 0.82 9.9 22.9 12 6.1 0.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Apt1 PF10351.9 OAJ22863.1 - 1.5 7.6 8.9 3 6.6 8.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain PH_9 PF15410.6 OAJ22865.1 - 3.1e-28 98.5 0.0 9e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 OAJ22865.1 - 4.1e-28 98.3 0.2 9.4e-28 97.1 0.2 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ22865.1 - 0.0084 16.6 0.0 0.029 14.9 0.0 1.8 1 1 0 1 1 1 1 PH domain DUF2340 PF10209.9 OAJ22866.1 - 6.9e-49 165.3 0.0 8.9e-49 164.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) GATA PF00320.27 OAJ22867.1 - 5.7e-13 48.2 5.7 1e-12 47.4 5.7 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF543 PF04418.12 OAJ22868.1 - 3.2e-29 100.7 0.3 7.3e-29 99.6 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4536 PF15055.6 OAJ22868.1 - 0.00027 21.1 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF883 PF05957.13 OAJ22868.1 - 0.64 10.7 2.7 26 5.5 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Putative_PNPOx PF01243.20 OAJ22869.1 - 2.6e-05 24.3 0.0 0.11 12.7 0.0 3.3 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 OAJ22869.1 - 0.2 11.7 0.0 0.71 10.0 0.0 1.8 1 1 0 1 1 1 0 Ferric reductase NAD binding domain KAP_NTPase PF07693.14 OAJ22871.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 OAJ22871.1 - 0.0018 18.7 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAJ22871.1 - 0.0038 17.2 0.1 0.0076 16.2 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OAJ22871.1 - 0.0099 16.4 0.0 0.028 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 OAJ22871.1 - 0.01 14.9 0.1 0.017 14.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 OAJ22871.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAJ22871.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ22871.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 OAJ22871.1 - 0.021 15.4 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 OAJ22871.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Arnt_C PF18583.1 OAJ22871.1 - 0.029 14.0 0.1 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Aminoarabinose transferase C-terminal domain NTPase_1 PF03266.15 OAJ22871.1 - 0.047 13.6 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 OAJ22871.1 - 0.057 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ22871.1 - 0.057 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ22871.1 - 0.099 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase Adeno_IVa2 PF02456.15 OAJ22871.1 - 0.1 11.3 0.2 0.16 10.7 0.2 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA PF00004.29 OAJ22871.1 - 0.17 12.3 0.1 0.7 10.3 0.0 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-rbx1 PF12678.7 OAJ22872.1 - 4.6e-06 26.8 2.5 1.1e-05 25.6 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ22872.1 - 4.6e-06 26.9 3.7 4.6e-06 26.9 3.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ22872.1 - 0.0001 22.1 2.2 0.0001 22.1 2.2 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ22872.1 - 0.0077 16.1 2.0 0.0077 16.1 2.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ22872.1 - 0.0098 15.7 1.8 0.0098 15.7 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ22872.1 - 0.01 15.4 5.3 0.023 14.3 5.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 OAJ22872.1 - 0.017 14.9 2.6 0.042 13.7 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ22872.1 - 0.043 13.8 5.9 0.042 13.8 1.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ22872.1 - 0.4 10.8 4.9 0.1 12.7 1.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ22872.1 - 1.1 9.0 5.7 0.62 9.9 0.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 OAJ22872.1 - 2.2 8.3 7.5 4.5 7.4 5.7 2.4 1 1 0 1 1 1 0 RING-type zinc-finger 3Beta_HSD PF01073.19 OAJ22873.1 - 1.7e-60 204.4 0.0 3e-56 190.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ22873.1 - 4.4e-25 88.5 0.0 6.7e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ22873.1 - 8.9e-12 45.0 0.0 5.7e-09 35.8 0.0 3.1 2 2 1 3 3 3 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAJ22873.1 - 7.1e-09 35.8 0.0 4.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAJ22873.1 - 2.1e-07 30.3 0.0 3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAJ22873.1 - 3.9e-07 29.5 0.2 7.6e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 OAJ22873.1 - 0.00052 20.0 0.0 0.0034 17.3 0.0 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ22873.1 - 0.0023 17.1 0.0 0.0098 15.0 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 OAJ22873.1 - 0.0081 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Cofilin_ADF PF00241.20 OAJ22874.1 - 3.6e-19 68.7 0.0 2.2e-08 34.0 0.0 2.7 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Pribosyltran PF00156.27 OAJ22875.1 - 4.9e-17 61.9 0.3 6.8e-17 61.4 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NABP PF07990.12 OAJ22875.1 - 0.0066 16.0 0.1 0.0092 15.6 0.1 1.2 1 0 0 1 1 1 1 Nucleic acid binding protein NABP PRTase_2 PF15609.6 OAJ22875.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase OTU PF02338.19 OAJ22876.1 - 1.6e-25 90.1 0.0 2.7e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAJ22876.1 - 0.066 12.7 0.0 11 5.3 0.0 2.3 2 1 0 2 2 2 0 Peptidase C65 Otubain DUF3618 PF12277.8 OAJ22876.1 - 1.9 8.8 10.5 2.9 8.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) OST3_OST6 PF04756.13 OAJ22877.1 - 5.3e-82 275.5 0.0 7.2e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OAJ22877.1 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin EpsG PF14897.6 OAJ22877.1 - 0.081 12.2 3.5 0.11 11.7 3.5 1.2 1 0 0 1 1 1 0 EpsG family Cyclin PF08613.11 OAJ22878.1 - 2.3e-29 102.9 0.2 4e-29 102.1 0.2 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ22878.1 - 0.00022 21.0 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DCB PF16213.5 OAJ22879.1 - 6.1e-42 143.3 10.3 2.5e-41 141.3 10.3 2.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OAJ22879.1 - 1.9e-40 138.3 7.7 3.3e-40 137.6 0.0 3.8 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAJ22879.1 - 9.8e-27 93.5 7.6 2.5e-16 59.0 3.3 3.7 4 0 0 4 4 4 3 C-terminal region of Mon2 protein RTP1_C1 PF10363.9 OAJ22879.1 - 0.00068 19.8 0.2 1.2 9.3 0.0 3.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1981 PF09324.10 OAJ22879.1 - 0.003 17.4 0.2 0.057 13.3 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) SIL1 PF16782.5 OAJ22879.1 - 0.13 11.5 0.9 0.48 9.6 0.4 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 MFS_1 PF07690.16 OAJ22880.1 - 1.2e-27 96.8 28.1 1.2e-27 96.8 28.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily COX6C PF02937.15 OAJ22880.1 - 0.095 12.8 1.0 0.86 9.8 0.0 2.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc DUF2678 PF10856.8 OAJ22880.1 - 0.87 9.5 4.3 8.4 6.4 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Oleosin PF01277.17 OAJ22880.1 - 1.8 8.4 7.5 38 4.1 0.0 2.8 2 1 0 2 2 2 0 Oleosin DUF4064 PF13273.6 OAJ22880.1 - 3.7 7.9 16.6 1.5 9.1 0.2 4.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Helicase_C PF00271.31 OAJ22881.1 - 1.1e-20 74.1 0.0 1.7e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3246 PF11596.8 OAJ22881.1 - 0.015 14.8 3.6 0.029 13.8 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PPP4R2 PF09184.11 OAJ22881.1 - 0.4 10.2 9.8 0.28 10.7 5.1 2.3 3 0 0 3 3 3 0 PPP4R2 CPSF100_C PF13299.6 OAJ22881.1 - 1.4 9.1 6.3 0.086 13.0 0.5 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 OAJ22881.1 - 5 5.1 7.5 7.3 4.6 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi 4HBT PF03061.22 OAJ22882.1 - 1.9e-10 40.9 0.0 3.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.19 OAJ22882.1 - 0.0042 16.6 0.3 0.01 15.4 0.1 1.7 2 0 0 2 2 2 1 MaoC like domain DUF3659 PF12396.8 OAJ22882.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) DnaJ_C PF01556.18 OAJ22883.1 - 4.5e-29 101.5 0.0 7e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ22883.1 - 3.2e-26 91.2 1.6 4.9e-26 90.6 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OAJ22883.1 - 0.027 14.4 0.4 0.064 13.2 0.1 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein PHD PF00628.29 OAJ22884.1 - 4e-10 39.4 8.1 7.9e-10 38.5 8.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 OAJ22884.1 - 0.00028 20.8 0.1 0.00028 20.8 0.1 2.3 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain UPF0184 PF03670.13 OAJ22884.1 - 0.038 14.4 0.8 0.038 14.4 0.8 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) PHD_2 PF13831.6 OAJ22884.1 - 0.22 11.1 2.5 0.41 10.3 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 OAJ22885.1 - 1.2e-31 109.2 5.2 1.2e-31 109.2 5.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAJ22885.1 - 8.2e-24 84.8 0.5 8.2e-24 84.8 0.5 4.3 4 1 0 4 4 4 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAJ22885.1 - 2.9e-23 81.9 4.1 2.9e-23 81.9 4.1 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 OAJ22885.1 - 1.2e-21 76.5 0.4 2.7e-21 75.4 0.4 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 OAJ22885.1 - 4.2e-13 48.6 1.9 4.2e-13 48.6 1.9 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 OAJ22885.1 - 1.8e-09 37.4 8.8 1.8e-09 37.4 8.8 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 OAJ22885.1 - 1.7e-07 31.6 0.0 5.6e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 PWWP domain Serglycin PF04360.12 OAJ22885.1 - 0.012 15.5 1.3 0.03 14.3 1.3 1.6 1 0 0 1 1 1 0 Serglycin Nop14 PF04147.12 OAJ22885.1 - 0.11 10.7 25.7 0.24 9.6 25.7 1.5 1 0 0 1 1 1 0 Nop14-like family C1_2 PF03107.16 OAJ22885.1 - 2.2 8.7 18.9 8.1 6.9 3.3 2.8 2 0 0 2 2 2 0 C1 domain AAA PF00004.29 OAJ22886.1 - 1.2e-46 158.4 0.0 1.2e-41 142.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ22886.1 - 5.9e-09 35.6 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ22886.1 - 2e-07 31.5 0.1 6.8e-05 23.3 0.0 3.8 4 0 0 4 4 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ22886.1 - 2.6e-05 24.4 0.0 7.6e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ22886.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ22886.1 - 0.00028 21.0 0.0 0.5 10.5 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 OAJ22886.1 - 0.00091 18.7 0.3 0.25 10.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ22886.1 - 0.0028 17.6 0.0 0.011 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ22886.1 - 0.007 16.6 0.1 0.11 12.7 0.1 2.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAJ22886.1 - 0.0095 15.7 0.7 1 9.0 0.0 3.2 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.6 OAJ22886.1 - 0.016 15.8 0.7 0.044 14.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 OAJ22886.1 - 0.026 14.1 0.5 0.24 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Bromodomain PF00439.25 OAJ22886.1 - 0.03 14.4 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 Bromodomain ABC_tran PF00005.27 OAJ22886.1 - 0.056 13.9 0.4 0.31 11.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 OAJ22886.1 - 0.064 13.4 0.0 0.064 13.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 OAJ22886.1 - 0.072 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 OAJ22886.1 - 0.085 12.9 0.3 0.2 11.6 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 OAJ22886.1 - 0.092 12.3 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 OAJ22886.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 OAJ22886.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 OAJ22886.1 - 0.13 12.2 0.0 0.89 9.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 OAJ22886.1 - 0.15 12.2 0.1 0.66 10.1 0.0 2.1 3 0 0 3 3 2 0 Torsin RuvB_N PF05496.12 OAJ22886.1 - 0.19 11.5 0.0 0.48 10.2 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 OAJ22886.1 - 0.33 10.7 0.0 0.33 10.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain HLH PF00010.26 OAJ22887.1 - 6e-13 48.5 10.8 7.1e-09 35.5 0.0 3.4 2 1 1 4 4 4 2 Helix-loop-helix DNA-binding domain Med3 PF11593.8 OAJ22887.1 - 0.0019 17.4 11.1 0.0019 17.4 11.1 5.3 5 1 0 6 6 6 1 Mediator complex subunit 3 fungal ThiF PF00899.21 OAJ22888.1 - 5.5e-73 245.3 0.3 1.5e-72 243.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBA_e1_thiolCys PF10585.9 OAJ22888.1 - 3.2e-12 46.9 0.3 5.3e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 OAJ22888.1 - 6.5e-05 23.5 0.2 0.00033 21.2 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 OAJ22888.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ22888.1 - 0.013 15.7 0.0 0.056 13.7 0.0 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAJ22888.1 - 0.029 14.8 0.0 0.094 13.2 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ArfGap PF01412.18 OAJ22889.1 - 1.5e-31 108.9 0.5 2.7e-31 108.0 0.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OAJ22889.1 - 5.1e-09 36.6 0.0 8.7e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 PH domain FAD_binding_4 PF01565.23 OAJ22890.1 - 5.2e-17 61.9 1.5 9.2e-17 61.1 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ22890.1 - 1.4e-08 34.7 0.2 3.2e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like RR_TM4-6 PF06459.12 OAJ22891.1 - 5.1 6.8 5.7 17 5.1 4.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Red1 PF07964.11 OAJ22891.1 - 9.4 4.3 8.5 12 3.9 8.5 1.1 1 0 0 1 1 1 0 Rec10 / Red1 WD40 PF00400.32 OAJ22892.1 - 8e-09 36.0 6.6 0.096 13.6 0.1 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat EF-hand_1 PF00036.32 OAJ22893.1 - 2.3e-42 139.4 13.1 1.4e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAJ22893.1 - 5.4e-36 122.9 3.4 2.2e-18 66.4 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ22893.1 - 6.8e-32 106.7 7.2 1.2e-09 37.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ22893.1 - 2e-31 107.6 11.8 1.4e-14 53.7 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAJ22893.1 - 4.3e-27 92.4 9.4 9.2e-07 28.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAJ22893.1 - 2.1e-16 60.0 0.2 1.9e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ22893.1 - 8.7e-10 38.5 1.2 3.1e-05 23.9 0.2 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAJ22893.1 - 8.5e-09 35.7 0.0 0.00082 19.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAJ22893.1 - 2.7e-06 27.3 1.7 0.038 14.0 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OAJ22893.1 - 9.5e-06 26.4 0.0 0.0046 17.8 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 OAJ22893.1 - 3.6e-05 23.8 0.5 0.00045 20.3 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 OAJ22893.1 - 0.00012 22.2 5.7 0.05 13.8 2.7 3.1 1 1 1 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 OAJ22893.1 - 0.0011 18.9 1.3 0.58 10.1 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein DUF1103 PF06513.11 OAJ22893.1 - 0.0015 18.2 2.4 0.0018 18.0 2.4 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.16 OAJ22893.1 - 0.0025 18.0 0.1 0.33 11.2 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAJ22893.1 - 0.0037 17.7 0.0 0.97 9.9 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 OAJ22893.1 - 0.0039 17.1 0.2 1.1 9.2 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 OAJ22893.1 - 0.0068 16.7 0.3 3.5 8.0 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 OAJ22893.1 - 0.0078 16.3 0.4 0.11 12.7 0.1 2.2 1 1 0 2 2 2 1 Transcription factor MotA, activation domain DUF5580 PF17743.1 OAJ22893.1 - 0.011 14.4 0.0 0.011 14.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 OAJ22893.1 - 0.02 14.9 0.5 17 5.5 0.0 3.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 dCache_2 PF08269.11 OAJ22893.1 - 0.027 13.7 0.1 1.3 8.1 0.1 2.3 1 1 0 2 2 2 0 Cache domain SurA_N_2 PF13623.6 OAJ22893.1 - 0.033 14.1 0.7 1.1 9.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 OAJ22893.1 - 0.043 13.5 0.2 0.079 12.6 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain EF-hand_14 PF17959.1 OAJ22893.1 - 0.049 14.0 0.2 14 6.1 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 OAJ22893.1 - 0.058 13.6 0.0 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) RuvA_C PF07499.13 OAJ22893.1 - 0.13 12.8 0.1 15 6.2 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain RloB PF13707.6 OAJ22893.1 - 0.15 12.2 0.9 1.1 9.4 0.9 2.1 1 1 0 1 1 1 0 RloB-like protein Sel1 PF08238.12 OAJ22894.1 - 3.2e-40 135.7 22.3 4.4e-07 30.4 0.4 8.5 8 0 0 8 8 8 7 Sel1 repeat NTF2 PF02136.20 OAJ22896.1 - 4.8e-31 107.8 0.0 7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 OAJ22896.1 - 0.00012 21.4 0.0 0.0002 20.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RRM_1 PF00076.22 OAJ22896.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ22896.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_walkeri-ASM164505v1/GCA_001645055.1_ASM164505v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_walkeri-ASM164505v1/GCA_001645055.1_ASM164505v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_walkeri-ASM164505v1/GCA_001645055.1_ASM164505v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_walkeri-ASM164505v1/GCA_001645055.1_ASM164505v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:15:52 2019 # [ok]