# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Condensation PF00668.15 OAI95157.1 - 4.4e-14 52.0 0.0 6e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain HhH-GPD PF00730.20 OAI95160.1 - 1.8e-14 53.9 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAI95160.1 - 0.023 14.3 0.3 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif PG_binding_2 PF08823.6 OAI95160.1 - 0.033 14.2 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain KRTAP PF11759.3 OAI95166.1 - 5 7.4 16.0 8.3 6.7 11.1 1.3 1 0 0 1 1 1 0 Keratin-associated matrix Ring_hydroxyl_B PF00866.13 OAI95169.1 - 2.6e-44 150.4 0.9 3e-44 150.2 0.6 1.0 1 0 0 1 1 1 1 Ring hydroxylating beta subunit Glyco_transf_21 PF13506.1 OAI95169.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Ring_hydroxyl_A PF00848.14 OAI95170.1 - 6.8e-05 22.6 0.0 7.8e-05 22.4 0.0 1.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) TPP_enzyme_N PF02776.13 OAI95174.1 - 8.5e-17 61.1 0.3 2.4e-12 46.6 0.2 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF3492 PF11997.3 OAI95176.1 - 5.8e-74 249.0 0.0 7.2e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) UBN2_2 PF14227.1 OAI95178.1 - 3.9e-07 29.6 0.2 6.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI95178.1 - 8.1e-05 22.3 13.2 0.012 15.5 0.5 2.7 3 0 0 3 3 3 2 Zinc knuckle UBN2 PF14223.1 OAI95178.1 - 0.00049 19.8 0.3 0.0008 19.1 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.1 OAI95178.1 - 0.0096 15.6 8.2 0.068 12.9 1.5 2.4 2 0 0 2 2 2 2 Zinc knuckle RVP PF00077.15 OAI95178.1 - 0.049 13.5 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.1 OAI95178.1 - 0.066 12.7 8.2 0.65 9.5 0.8 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI95178.1 - 0.49 10.1 9.3 1.1 8.9 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 OAI95178.1 - 4.8 6.9 11.2 9.5 5.9 1.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Peptidase_M17 PF00883.16 OAI95179.1 - 1.1e-45 155.9 0.0 1.2e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF2968 PF11180.3 OAI95179.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Polysacc_deac_1 PF01522.16 OAI95190.1 - 2.8e-05 23.7 0.0 6.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase CHZ PF09649.5 OAI95201.1 - 0.004 16.3 2.0 0.64 9.3 0.1 2.7 2 0 0 2 2 2 2 Histone chaperone domain CHZ SAICAR_synt PF01259.13 OAI95201.1 - 0.0079 15.3 4.5 0.39 9.7 0.2 2.1 2 0 0 2 2 2 2 SAICAR synthetase CDK2AP PF09806.4 OAI95201.1 - 3.2 7.9 30.3 1.7 8.8 6.8 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF4095 PF13338.1 OAI95205.1 - 1.2e-08 35.1 0.2 2.6e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4095) DUF4072 PF13284.1 OAI95205.1 - 0.44 10.7 5.3 32 4.8 0.4 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) DUF1302 PF06980.6 OAI95211.1 - 4.5e-43 147.6 1.5 5e-43 147.4 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) IclR PF01614.13 OAI95214.1 - 2.5e-10 40.1 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional regulator YhfH PF14149.1 OAI95227.1 - 0.077 12.7 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 YhfH-like protein FAM217 PF15344.1 OAI95232.1 - 0.23 10.9 9.1 0.33 10.4 6.3 1.2 1 0 0 1 1 1 0 FAM217 family FlxA PF14282.1 OAI95232.1 - 0.52 10.2 11.5 1.3 8.9 7.9 1.8 1 1 0 1 1 1 0 FlxA-like protein NAM-associated PF14303.1 OAI95232.1 - 0.83 9.9 9.8 1.4 9.2 6.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SOBP PF15279.1 OAI95232.1 - 8.2 6.7 9.2 10 6.4 6.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RRN3 PF05327.6 OAI95234.1 - 3.4e-25 88.1 0.0 3.8e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 GMC_oxred_N PF00732.14 OAI95238.1 - 4.6e-24 85.0 0.0 5.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF1215 PF06744.7 OAI95245.1 - 0.004 16.7 0.0 0.0098 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1215) Drf_FH1 PF06346.7 OAI95247.1 - 5e-15 55.3 98.8 1.7e-07 30.8 18.1 4.1 1 1 1 3 3 3 3 Formin Homology Region 1 MFS_1 PF07690.11 OAI95249.1 - 3.5e-20 72.0 39.5 3.5e-20 72.0 27.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 OAI95249.1 - 0.076 12.0 1.5 0.35 9.9 1.1 2.1 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Vps51 PF08700.6 OAI95253.1 - 8.9e-16 57.5 0.3 1.9e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 OAI95253.1 - 5.3e-07 29.5 1.2 6.4e-07 29.3 0.2 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Cation_efflux PF01545.16 OAI95255.1 - 2.1e-05 23.7 0.1 2.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family SUZ PF12752.2 OAI95255.1 - 0.3 11.6 5.6 0.67 10.5 3.9 1.5 1 0 0 1 1 1 0 SUZ domain DUF1329 PF07044.6 OAI95256.1 - 1e-57 195.7 0.1 1.1e-57 195.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1329) tRNA-synt_1 PF00133.17 OAI95261.1 - 1.2e-08 33.4 0.0 2.2e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) E1-E2_ATPase PF00122.15 OAI95263.1 - 3.4e-17 62.2 1.7 3.7e-17 62.1 0.1 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Peptidase_M50B PF13398.1 OAI95263.1 - 0.019 14.3 0.6 0.023 14.0 0.4 1.1 1 0 0 1 1 1 0 Peptidase M50B-like Conotoxin PF02950.12 OAI95275.1 - 0.007 17.1 0.1 0.0095 16.7 0.0 1.1 1 0 0 1 1 1 1 Conotoxin LEAP-2 PF07359.6 OAI95275.1 - 0.042 13.4 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) NVEALA PF14055.1 OAI95275.1 - 0.057 13.1 0.9 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 NVEALA protein IgaA PF07095.6 OAI95275.1 - 0.12 10.1 0.0 0.14 9.8 0.0 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Nodulin_late PF07127.6 OAI95275.1 - 0.18 11.9 2.7 0.72 10.0 0.3 2.2 2 0 0 2 2 2 0 Late nodulin protein Methyltransf_21 PF05050.7 OAI95291.1 - 1.4e-20 73.9 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 OAI95291.1 - 7.9e-08 32.8 0.0 1.5e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAI95291.1 - 3e-07 30.2 0.0 4.6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein V_cholerae_RfbT PF05575.6 OAI95291.1 - 5.8e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein Methyltransf_4 PF02390.12 OAI95291.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAI95291.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 OAI95291.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PIG-L PF02585.12 OAI95295.1 - 4.2e-07 30.5 0.1 7.5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF2384 PF09722.5 OAI95296.1 - 3e-05 23.7 0.0 8.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) DUF1192 PF06698.6 OAI95298.1 - 0.031 14.0 1.2 0.072 12.9 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pox_Ag35 PF03286.9 OAI95298.1 - 0.22 11.0 3.0 0.37 10.2 2.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Porin_4 PF13609.1 OAI95302.1 - 7.1e-19 68.4 2.8 8.3e-19 68.2 1.9 1.0 1 0 0 1 1 1 1 Gram-negative porin Porin_1 PF00267.16 OAI95302.1 - 1.4e-14 54.1 0.2 1.6e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Gram-negative porin Porin_O_P PF07396.6 OAI95302.1 - 0.0015 17.4 0.4 0.0017 17.3 0.3 1.0 1 0 0 1 1 1 1 Phosphate-selective porin O and P MutS_IV PF05190.13 OAI95316.1 - 4.8e-05 23.4 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 MutS family domain IV RGCC PF15151.1 OAI95317.1 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family HlyD PF00529.15 OAI95319.1 - 0.82 8.9 12.6 1.3 8.2 8.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein MULE PF10551.4 OAI95361.1 - 1.6e-19 69.8 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI95361.1 - 8.5e-09 34.4 0.1 1.7e-08 33.4 0.0 1.4 2 0 0 2 2 2 1 Transposase, Mutator family TEX19 PF15553.1 OAI95367.1 - 0.0071 16.2 1.8 0.01 15.6 1.2 1.2 1 0 0 1 1 1 1 Testis-expressed protein 19 DNA_pol_phi PF04931.8 OAI95367.1 - 1 7.0 2.6 1.2 6.7 1.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF605 PF04652.11 OAI95367.1 - 2.4 7.4 15.3 3 7.1 10.6 1.1 1 0 0 1 1 1 0 Vta1 like Drf_FH1 PF06346.7 OAI95375.1 - 8.4e-09 35.1 74.8 8.5e-09 35.1 17.9 4.0 1 1 0 2 2 2 1 Formin Homology Region 1 UBN2 PF14223.1 OAI95383.1 - 4.9e-05 23.1 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAI95383.1 - 0.0055 16.2 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3918 PF13056.1 OAI95386.1 - 0.012 14.9 0.9 0.016 14.4 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3918) TetR_N PF00440.18 OAI95392.1 - 4e-10 39.1 0.1 7.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family UBN2_2 PF14227.1 OAI95397.1 - 7.3e-07 28.7 0.1 1.2e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI95397.1 - 9.2e-05 22.1 7.9 0.015 15.2 0.5 2.6 2 0 0 2 2 2 2 Zinc knuckle UBN2 PF14223.1 OAI95397.1 - 0.00071 19.3 0.2 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.1 OAI95397.1 - 0.0066 15.9 7.9 0.28 10.7 0.5 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 OAI95397.1 - 0.017 14.8 8.2 0.058 13.1 1.1 2.4 2 0 0 2 2 2 0 Zinc knuckle RVP PF00077.15 OAI95397.1 - 0.13 12.1 0.1 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 OAI95397.1 - 0.37 10.4 7.4 1.4 8.6 1.0 2.5 2 0 0 2 2 2 0 Zinc knuckle Sulfatase PF00884.18 OAI95401.1 - 2.8e-28 99.0 0.0 3e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 OAI95401.1 - 0.048 12.9 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Retrotrans_gag PF03732.12 OAI95407.1 - 4.7e-11 42.6 0.6 9.1e-11 41.6 0.2 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI95407.1 - 0.0029 17.4 0.2 0.0048 16.7 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI95407.1 - 0.022 14.4 0.4 0.049 13.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Phage_integrase PF00589.17 OAI95422.1 - 1.6e-06 27.8 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family IF2_N PF04760.10 OAI95428.1 - 0.023 14.3 0.4 0.038 13.6 0.3 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Peptidase_S10 PF00450.17 OAI95432.1 - 7.2e-11 41.8 0.0 8.5e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Rad60-SLD PF11976.3 OAI95438.1 - 2.6e-12 46.2 0.0 6.1e-06 25.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like GAF PF01590.21 OAI95446.1 - 0.051 13.6 0.0 0.054 13.6 0.0 1.1 1 0 0 1 1 1 0 GAF domain gag-asp_proteas PF13975.1 OAI95449.1 - 3.3e-10 39.6 0.2 9.8e-10 38.1 0.1 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 OAI95449.1 - 6.9e-08 32.0 1.8 1.3e-07 31.1 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAI95449.1 - 3.9e-07 30.4 0.5 7.7e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI95449.1 - 0.0016 18.2 0.1 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI95449.1 - 0.006 16.1 0.0 0.02 14.4 0.0 1.9 2 1 0 2 2 2 1 Aspartyl protease Peptidase_A2B PF12384.3 OAI95449.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase zf-CCHC_2 PF13696.1 OAI95449.1 - 0.032 13.7 1.6 0.07 12.6 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 OAI95449.1 - 0.048 13.3 1.5 0.087 12.5 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 OAI95449.1 - 0.097 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 OAI95449.1 - 0.12 12.0 0.7 0.24 11.1 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Pil1 PF13805.1 OAI95462.1 - 1.3e-25 90.0 0.0 1.7e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 GAS PF13851.1 OAI95462.1 - 0.88 8.7 4.8 0.35 10.0 1.7 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HA2 PF04408.18 OAI95464.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAI95464.1 - 0.024 14.5 4.0 1.4 8.8 2.8 2.3 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Sigma70_r1_2 PF00140.15 OAI95468.1 - 0.0064 16.1 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 adh_short PF00106.20 OAI95472.1 - 2.4e-08 34.0 0.5 8.1e-07 29.1 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAI95472.1 - 1.2e-06 28.7 0.1 1.6e-06 28.2 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAI95472.1 - 4.7e-05 22.9 0.0 5.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAI95472.1 - 0.001 18.9 0.1 0.0019 18.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SPOR PF05036.8 OAI95472.1 - 0.069 13.3 0.0 2.5 8.3 0.0 2.3 2 1 0 2 2 2 0 Sporulation related domain LytR_C PF13399.1 OAI95472.1 - 0.097 13.0 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator RmlD_sub_bind PF04321.12 OAI95472.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain RVT_3 PF13456.1 OAI95480.1 - 0.035 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like MCPsignal PF00015.16 OAI95498.1 - 6.6e-29 100.9 9.3 6.6e-29 100.9 6.4 2.1 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain LacI PF00356.16 OAI95498.1 - 4.7e-05 22.9 0.2 0.00014 21.3 0.2 1.8 1 0 0 1 1 1 1 Bacterial regulatory proteins, lacI family DUF2791 PF10923.3 OAI95498.1 - 0.023 13.2 0.3 0.023 13.2 0.2 1.8 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) Cluap1 PF10234.4 OAI95498.1 - 0.71 9.0 9.9 0.12 11.5 0.2 2.5 2 1 0 2 2 2 0 Clusterin-associated protein-1 Baculo_PEP_C PF04513.7 OAI95498.1 - 2 8.2 13.0 0.21 11.4 1.1 3.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NDUFA12 PF05071.11 OAI95503.1 - 0.072 13.5 0.1 0.085 13.3 0.0 1.1 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 EF-hand_7 PF13499.1 OAI95512.1 - 2.3e-05 24.4 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAI95512.1 - 6.6e-05 21.9 0.1 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAI95512.1 - 0.00032 20.3 0.1 0.00061 19.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 OAI95512.1 - 0.0017 17.5 0.4 0.0036 16.5 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 OAI95512.1 - 0.095 12.3 0.3 0.69 9.5 0.1 2.3 2 1 1 3 3 3 0 EF-hand domain pair NmrA PF05368.8 OAI95513.1 - 6.9e-08 32.0 0.5 7.9e-08 31.8 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAI95513.1 - 1e-06 28.9 0.8 1.1e-06 28.7 0.6 1.0 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAI95513.1 - 8.4e-05 22.5 1.1 9.3e-05 22.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI95513.1 - 0.00021 21.0 0.6 0.00023 20.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 OAI95513.1 - 0.00056 20.0 0.3 0.00056 20.0 0.2 1.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 OAI95513.1 - 0.00075 19.4 0.2 0.00093 19.1 0.1 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 OAI95513.1 - 0.0008 18.4 0.0 0.00083 18.3 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAI95513.1 - 0.0015 17.9 0.1 0.006 16.0 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAI95513.1 - 0.0088 16.0 0.2 0.0097 15.8 0.1 1.1 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 OAI95513.1 - 0.0098 14.8 0.1 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 OAI95513.1 - 0.013 14.5 0.4 0.014 14.4 0.2 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 OAI95513.1 - 0.021 15.3 0.1 0.025 15.1 0.0 1.0 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Polysacc_synt_2 PF02719.10 OAI95513.1 - 0.056 12.3 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 OAI95513.1 - 0.099 11.3 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HxlR PF01638.12 OAI95514.1 - 4.2e-28 96.8 0.0 5.1e-28 96.5 0.0 1.1 1 0 0 1 1 1 1 HxlR-like helix-turn-helix HTH_20 PF12840.2 OAI95514.1 - 3.4e-05 23.5 0.8 0.00018 21.2 0.3 2.1 1 1 1 2 2 2 1 Helix-turn-helix domain MarR PF01047.17 OAI95514.1 - 0.0065 16.1 0.2 0.0096 15.6 0.1 1.3 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 OAI95514.1 - 0.01 15.5 0.7 0.022 14.4 0.5 1.7 1 1 0 1 1 1 0 MarR family HTH_12 PF08461.5 OAI95514.1 - 0.014 15.1 0.2 0.033 13.9 0.1 1.7 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Stn1_C PF12659.2 OAI95514.1 - 0.045 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH Rrf2 PF02082.15 OAI95514.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator PadR PF03551.9 OAI95514.1 - 0.081 12.7 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family TrmB PF01978.14 OAI95514.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB ACT PF01842.20 OAI95515.1 - 1.2e-06 27.9 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAI95515.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 OAI95515.1 - 0.072 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ACT domain Asp PF00026.18 OAI95525.1 - 1e-37 130.0 0.0 2.3e-37 128.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI95525.1 - 5.6e-05 23.1 0.8 0.00061 19.7 0.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal RVP PF00077.15 OAI95525.1 - 0.084 12.7 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF4505 PF14956.1 OAI95534.1 - 0.0096 15.5 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Dermcidin PF15291.1 OAI95559.1 - 0.38 10.9 3.4 13 6.0 1.6 2.1 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Retrotrans_gag PF03732.12 OAI95565.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein PAS_4 PF08448.5 OAI95567.1 - 5.8e-09 35.9 0.0 9.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 OAI95567.1 - 3.5e-08 33.3 2.5 2.4e-07 30.6 0.0 3.4 3 1 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 OAI95567.1 - 1.1e-05 25.1 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 OAI95567.1 - 0.00022 21.5 0.0 0.00066 20.0 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 OAI95567.1 - 0.00022 20.9 0.0 0.00083 19.1 0.0 2.0 1 0 0 1 1 1 1 PAS domain DUF615 PF04751.9 OAI95567.1 - 0.0019 17.8 1.5 0.71 9.5 0.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF615) PAS_7 PF12860.2 OAI95567.1 - 0.032 14.2 0.1 0.5 10.3 0.1 2.6 1 1 0 1 1 1 0 PAS fold PAS_10 PF13596.1 OAI95567.1 - 0.039 14.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 PAS domain ALIX_LYPXL_bnd PF13949.1 OAI95567.1 - 0.087 11.7 3.8 2.3 7.0 2.0 2.6 2 1 0 3 3 3 0 ALIX V-shaped domain binding to HIV HHH PF00633.18 OAI95574.1 - 0.053 13.2 0.1 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Het-C PF07217.6 OAI95581.1 - 1.2e-39 136.0 0.0 1.3e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RVT_2 PF07727.9 OAI95584.1 - 1.7e-38 132.0 0.0 2.2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HTH_8 PF02954.14 OAI95589.1 - 0.038 13.5 0.1 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family zf-Sec23_Sec24 PF04810.10 OAI95594.1 - 0.088 12.3 3.6 0.63 9.6 2.4 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger PIGA PF08288.7 OAI95607.1 - 1.7e-12 47.5 0.1 2.6e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.1 OAI95607.1 - 4e-07 29.9 0.0 5.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAI95607.1 - 0.00025 21.2 0.0 0.00035 20.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 OAI95607.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain TRAP_alpha PF03896.11 OAI95614.1 - 0.097 11.6 1.7 0.11 11.4 1.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 OAI95614.1 - 0.18 12.0 6.1 0.27 11.4 4.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAI95614.1 - 0.41 10.2 5.0 0.49 9.9 3.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2890 PF11081.3 OAI95614.1 - 0.53 10.3 6.0 0.039 14.0 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 OAI95614.1 - 0.85 9.1 5.4 1.2 8.6 3.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 OAI95614.1 - 1.2 8.7 6.1 1.5 8.4 4.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_C48 PF02902.14 OAI95617.1 - 0.0005 19.7 1.2 0.0012 18.5 0.8 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pec_lyase_C PF00544.14 OAI95619.1 - 4.6e-53 179.6 3.8 6.6e-53 179.1 2.7 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 OAI95619.1 - 4.1e-05 23.3 25.4 0.0035 17.0 16.1 2.7 1 1 0 1 1 1 1 Right handed beta helix region Med15 PF09606.5 OAI95624.1 - 3.5 5.7 80.2 4.8 5.2 55.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 OAI95624.1 - 3.5 6.7 32.2 4.8 6.3 22.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF940 PF06082.6 OAI95624.1 - 5.3 5.4 26.1 6.5 5.1 18.1 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) PLRV_ORF5 PF01690.12 OAI95624.1 - 6.9 5.6 26.3 9.6 5.2 18.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peptidase_C48 PF02902.14 OAI95627.1 - 0.088 12.4 1.6 1.8 8.1 0.8 2.1 1 1 1 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain Topo_Zn_Ribbon PF08272.6 OAI95627.1 - 0.21 10.9 6.0 2.9 7.3 0.5 2.3 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Nop14 PF04147.7 OAI95632.1 - 3.9e-63 213.6 6.7 3.9e-63 213.6 4.6 1.5 1 1 0 1 1 1 1 Nop14-like family Macoilin PF09726.4 OAI95632.1 - 1.9 6.6 10.7 0.15 10.3 3.6 1.7 1 1 0 2 2 2 0 Transmembrane protein MULE PF10551.4 OAI95633.1 - 8.9e-09 35.4 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI95633.1 - 0.0053 15.3 0.0 0.0079 14.7 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Aminotran_1_2 PF00155.16 OAI95635.1 - 1.1e-19 70.6 0.0 1.5e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GntR PF00392.16 OAI95635.1 - 5.7e-12 44.8 0.0 1.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_11 PF08279.7 OAI95635.1 - 0.013 15.0 0.0 0.045 13.3 0.0 2.0 1 0 0 1 1 1 0 HTH domain HTH_41 PF14502.1 OAI95635.1 - 0.015 14.8 0.2 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Aminotran_5 PF00266.14 OAI95635.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Methyltransf_26 PF13659.1 OAI95635.1 - 0.092 12.7 0.2 0.61 10.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain HTH_36 PF13730.1 OAI95635.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ORC6 PF05460.8 OAI95646.1 - 0.0077 15.3 2.6 0.0099 15.0 1.8 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF4280 PF14107.1 OAI95657.1 - 9.4e-33 112.7 0.1 1.1e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4280) Transthyretin PF00576.16 OAI95658.1 - 7.1e-36 122.5 0.0 8.2e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family MG1 PF11974.3 OAI95658.1 - 0.00055 20.4 0.0 0.00071 20.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain DUF4469 PF14734.1 OAI95658.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold A2M_N PF01835.14 OAI95658.1 - 0.016 15.4 0.1 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 MG2 domain Big_1 PF02369.11 OAI95658.1 - 0.021 14.7 0.1 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF824 PF05688.6 OAI95658.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) CarboxypepD_reg PF13620.1 OAI95658.1 - 0.073 13.1 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain CopC PF04234.7 OAI95658.1 - 0.14 12.7 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 CopC domain Cna_B PF05738.8 OAI95658.1 - 0.16 11.7 1.0 0.31 10.8 0.7 1.5 1 1 0 1 1 1 0 Cna protein B-type domain zf-C2H2 PF00096.21 OAI95671.1 - 0.00067 19.8 3.8 0.21 11.9 0.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI95671.1 - 0.065 13.5 5.6 2.7 8.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1768 PF08719.6 OAI95675.1 - 4.4e-16 59.0 0.1 5.2e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) rve PF00665.21 OAI95678.1 - 1.3e-20 73.7 0.0 3.4e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95678.1 - 0.055 12.9 0.1 0.6 9.6 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain OrfB_Zn_ribbon PF07282.6 OAI95688.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Rad60-SLD PF11976.3 OAI95690.1 - 1.8e-17 62.7 0.0 2.2e-05 24.0 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAI95690.1 - 0.0017 17.6 0.0 12 5.4 0.0 3.8 4 0 0 4 4 4 2 Ubiquitin family Asp_protease_2 PF13650.1 OAI95693.1 - 1.1e-10 41.8 0.1 1.6e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI95693.1 - 1e-06 28.4 0.0 3.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI95693.1 - 1.1e-05 25.2 0.1 2.1e-05 24.3 0.1 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI95693.1 - 1.7e-05 24.4 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 OAI95693.1 - 0.041 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Sugar_tr PF00083.19 OAI95694.1 - 1.1e-55 189.0 17.5 8.9e-55 186.0 12.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter YqhR PF11085.3 OAI95694.1 - 0.0021 17.6 0.6 0.0045 16.5 0.4 1.5 1 0 0 1 1 1 1 Conserved membrane protein YqhR Cutinase PF01083.17 OAI95695.1 - 8.1e-17 61.5 0.2 9.8e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAI95695.1 - 0.017 14.5 0.1 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.2 OAI95695.1 - 0.018 14.9 0.1 0.25 11.1 0.1 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI95695.1 - 0.02 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 OAI95695.1 - 0.03 14.5 0.1 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain VID27 PF08553.5 OAI95699.1 - 3e-68 230.8 8.8 3.9e-68 230.4 6.1 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein PDE6_gamma PF04868.7 OAI95699.1 - 3.7 7.4 5.2 0.43 10.4 0.2 1.9 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit DUF3275 PF11679.3 OAI95699.1 - 7.4 6.1 13.1 0.24 11.0 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) SprA-related PF12118.3 OAI95703.1 - 1.6e-07 30.9 65.9 5.2e-07 29.2 26.7 2.4 2 0 0 2 2 2 2 SprA-related family UPF0564 PF10595.4 OAI95703.1 - 2.9e-06 26.4 20.1 2.9e-06 26.4 13.9 2.2 2 0 0 2 2 1 1 Uncharacterised protein family UPF0564 Tim54 PF11711.3 OAI95703.1 - 0.00079 18.1 7.9 0.00079 18.1 5.5 2.1 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 OAI95703.1 - 0.0019 18.0 26.2 0.038 13.8 11.9 2.5 2 0 0 2 2 2 2 DDHD domain Herpes_UL87 PF03043.9 OAI95703.1 - 0.0025 16.2 11.1 0.0039 15.6 7.7 1.2 1 0 0 1 1 1 1 Herpesvirus UL87 family Spore_coat_CotO PF14153.1 OAI95703.1 - 0.012 15.1 51.2 0.017 14.5 22.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 OAI95703.1 - 0.034 11.8 30.8 0.036 11.8 13.8 2.0 2 0 0 2 2 2 0 Ycf1 Macoilin PF09726.4 OAI95703.1 - 0.11 10.7 27.7 0.093 11.0 10.1 2.1 2 0 0 2 2 2 0 Transmembrane protein DUF966 PF06136.8 OAI95703.1 - 0.12 11.7 27.3 0.41 10.0 11.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Bud13 PF09736.4 OAI95703.1 - 0.22 11.7 47.4 1.6 9.0 5.9 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF2052 PF09747.4 OAI95703.1 - 0.22 11.4 44.2 0.25 11.2 3.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4045 PF13254.1 OAI95703.1 - 0.25 10.6 32.0 0.65 9.2 15.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 OAI95703.1 - 0.28 10.8 41.5 1.5 8.3 19.4 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SAPS PF04499.10 OAI95703.1 - 0.48 8.9 29.0 0.34 9.4 12.6 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein FHIPEP PF00771.15 OAI95703.1 - 0.48 8.6 24.0 0.32 9.2 8.5 2.1 2 0 0 2 2 2 0 FHIPEP family GAGA_bind PF06217.7 OAI95703.1 - 0.5 10.2 34.2 2.4 8.0 16.9 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family CDC45 PF02724.9 OAI95703.1 - 0.76 7.7 35.1 1 7.3 2.4 2.0 2 0 0 2 2 2 0 CDC45-like protein AUX_IAA PF02309.11 OAI95703.1 - 1.4 8.6 31.7 4.2 7.0 1.4 2.3 2 0 0 2 2 2 0 AUX/IAA family MRP-S31 PF15433.1 OAI95703.1 - 1.5 8.1 42.2 0.22 10.8 2.9 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Otopetrin PF03189.8 OAI95703.1 - 2.6 6.9 14.8 0.58 9.0 3.8 2.1 2 0 0 2 2 2 0 Otopetrin FLO_LFY PF01698.11 OAI95703.1 - 2.8 6.6 37.6 2.6 6.7 2.7 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein TT_ORF1 PF02956.9 OAI95703.1 - 3.3 6.0 32.9 2.1 6.6 2.9 2.2 2 0 0 2 2 2 0 TT viral orf 1 BNR_3 PF13859.1 OAI95703.1 - 3.9 6.4 14.0 5.1 6.0 5.8 2.3 2 0 0 2 2 2 0 BNR repeat-like domain FAM60A PF15396.1 OAI95703.1 - 4.8 6.8 34.1 1.2 8.7 1.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RR_TM4-6 PF06459.7 OAI95703.1 - 7.2 6.4 39.1 1.5 8.6 2.6 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 OAI95703.1 - 9.6 5.5 47.1 4.8 6.5 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF972 PF06156.8 OAI95705.1 - 2.6 8.4 5.6 2.5 8.5 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIVA PF05103.8 OAI95711.1 - 0.22 11.5 1.7 0.26 11.3 1.1 1.1 1 0 0 1 1 1 0 DivIVA protein ERCC4 PF02732.10 OAI95715.1 - 3e-25 88.6 0.0 4.9e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.11 OAI95715.1 - 0.0088 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Acyl-CoA_dh_M PF02770.14 OAI95722.1 - 0.00021 20.7 0.9 0.0005 19.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 OAI95722.1 - 0.00068 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal 4HBT_3 PF13622.1 OAI95727.1 - 2.2e-19 70.2 2.7 3e-19 69.7 1.9 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PH_5 PF15405.1 OAI95732.1 - 0.041 13.8 0.2 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain PAT1 PF09770.4 OAI95732.1 - 0.15 10.2 21.8 0.21 9.8 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 OAI95732.1 - 9.9 5.9 9.8 15 5.3 6.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rieske PF00355.21 OAI95738.1 - 0.0084 15.6 0.8 3.4 7.3 0.0 2.6 3 0 0 3 3 3 2 Rieske [2Fe-2S] domain Pox_A11 PF05061.8 OAI95745.1 - 0.33 9.9 2.7 0.39 9.7 1.9 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein NUC129 PF08157.6 OAI95747.1 - 0.00031 20.5 0.1 0.00066 19.5 0.1 1.5 1 0 0 1 1 1 1 NUC129 domain RTC4 PF14474.1 OAI95747.1 - 0.00048 20.0 0.0 0.00096 19.0 0.0 1.5 1 1 0 1 1 1 1 RTC4-like domain E1-E2_ATPase PF00122.15 OAI95752.1 - 0.0044 16.0 0.2 0.037 13.0 0.1 2.1 1 1 0 1 1 1 1 E1-E2 ATPase DUF1418 PF07214.7 OAI95752.1 - 0.1 12.2 0.7 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) RVT_2 PF07727.9 OAI95759.1 - 2.2e-90 301.9 0.0 2.7e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sugar_tr PF00083.19 OAI95763.1 - 3.2e-08 32.5 1.6 4.1e-08 32.2 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAI95763.1 - 2e-05 23.4 0.3 2.2e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAI95763.1 - 0.018 13.2 0.4 0.021 13.0 0.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Troponin-I_N PF11636.3 OAI95764.1 - 7.7 6.3 11.4 23 4.8 7.9 1.9 1 1 0 1 1 1 0 Troponin I residues 1-32 Arylesterase PF01731.15 OAI95773.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Arylesterase Helicase_C PF00271.26 OAI95777.1 - 9.5e-15 54.2 0.0 1.8e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 OAI95777.1 - 6.5e-13 48.2 0.0 1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Dicer dimerisation domain dsrm PF00035.20 OAI95777.1 - 0.009 16.5 0.0 0.024 15.2 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif 2H-phosphodiest PF08975.5 OAI95777.1 - 0.079 12.7 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) Tyrosinase PF00264.15 OAI95784.1 - 1.3e-19 71.2 1.3 1.6e-19 71.0 0.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_hydro_88 PF07470.8 OAI95789.1 - 3.2e-11 42.8 0.5 3.7e-10 39.3 0.1 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 PMT_2 PF13231.1 OAI95796.1 - 1.2e-17 64.2 9.2 1.2e-17 64.2 6.4 1.5 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 OAI95796.1 - 2.2e-13 50.1 5.2 2.6e-13 49.9 3.6 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3231 PF11553.3 OAI95805.1 - 0.091 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) MerR_1 PF13411.1 OAI95807.1 - 4.8e-13 48.6 0.3 8.8e-13 47.8 0.0 1.5 2 0 0 2 2 2 1 MerR HTH family regulatory protein MerR PF00376.18 OAI95807.1 - 3.8e-09 35.9 1.3 3.8e-09 35.9 0.9 1.7 2 0 0 2 2 2 1 MerR family regulatory protein MerR-DNA-bind PF09278.6 OAI95807.1 - 7.9e-06 26.1 0.7 1e-05 25.8 0.5 1.2 1 0 0 1 1 1 1 MerR, DNA binding AcylCoA_DH_N PF12418.3 OAI95817.1 - 0.026 14.2 0.4 0.064 12.9 0.1 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase N terminal Toprim PF01751.17 OAI95818.1 - 0.03 14.2 0.0 0.037 14.0 0.0 1.1 1 0 0 1 1 1 0 Toprim domain Glyoxalase_2 PF12681.2 OAI95819.1 - 7.3e-09 36.1 0.0 9.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAI95819.1 - 0.0019 18.1 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SOG2 PF10428.4 OAI95822.1 - 0.0086 14.7 6.0 0.012 14.3 4.1 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein Band_3_cyto PF07565.8 OAI95822.1 - 0.022 14.2 0.2 0.034 13.6 0.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sporozoite_P67 PF05642.6 OAI95822.1 - 0.03 12.2 10.7 0.038 11.8 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRCC PF10253.4 OAI95822.1 - 0.054 14.1 2.0 0.07 13.8 1.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting rve PF00665.21 OAI95832.1 - 1.4e-16 60.6 0.0 2.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95832.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF3505 PF12013.3 OAI95834.1 - 3.1e-10 40.2 1.1 5.5e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-CHY PF05495.7 OAI95834.1 - 0.022 14.9 1.8 0.29 11.3 0.3 2.2 2 0 0 2 2 2 0 CHY zinc finger NAPRTase PF04095.11 OAI95846.1 - 4.3e-22 78.5 0.1 3.5e-12 46.1 0.0 2.0 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family RFX5_DNA_bdg PF14621.1 OAI95852.1 - 0.028 14.0 2.5 0.035 13.6 1.8 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain AT_hook PF02178.14 OAI95852.1 - 0.15 11.8 3.7 0.38 10.5 2.6 1.7 1 0 0 1 1 1 0 AT hook motif RVT_2 PF07727.9 OAI95857.1 - 2.1e-51 174.2 0.1 2.9e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI95857.1 - 2.2e-19 69.7 0.0 4.6e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAI95857.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.12 OAI95860.1 - 5e-11 42.5 0.6 1e-10 41.5 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI95860.1 - 0.0023 17.7 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI95860.1 - 0.025 14.2 0.2 0.054 13.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF2618 PF10940.3 OAI95861.1 - 0.025 14.3 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) O-antigen_lig PF13425.1 OAI95862.1 - 2.1e-15 56.9 8.6 2.1e-15 56.9 6.0 3.1 2 2 1 3 3 3 1 O-antigen ligase like membrane protein Wzy_C PF04932.10 OAI95862.1 - 5.2e-06 26.3 13.7 5.2e-06 26.3 9.5 3.2 3 1 0 3 3 3 1 O-Antigen ligase CDK2AP PF09806.4 OAI95865.1 - 0.048 13.8 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein LON PF02190.11 OAI95875.1 - 3.2e-19 69.4 0.0 4.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 OAI95875.1 - 4.8e-09 36.1 9.1 1.1e-08 34.8 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI95875.1 - 1.3e-08 34.4 10.3 3.2e-08 33.2 7.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAI95875.1 - 1.8e-07 30.6 5.4 3.2e-07 29.9 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI95875.1 - 1.2e-06 28.1 8.3 2.2e-06 27.2 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAI95875.1 - 2.7e-06 26.9 8.2 4.9e-06 26.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAI95875.1 - 4.5e-05 23.2 9.8 9.4e-05 22.2 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAI95875.1 - 0.00013 21.4 3.0 0.00032 20.2 2.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 OAI95875.1 - 0.0011 18.6 2.0 0.002 17.8 1.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 OAI95875.1 - 0.0028 17.1 5.3 0.0075 15.7 3.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 OAI95875.1 - 0.01 15.5 4.8 0.025 14.2 3.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger UPF0731 PF14982.1 OAI95875.1 - 0.023 14.5 6.0 0.46 10.4 0.9 2.8 2 0 0 2 2 2 0 UPF0731 family zf-P11 PF03854.9 OAI95875.1 - 0.048 13.1 7.8 0.095 12.1 5.4 1.5 1 0 0 1 1 1 0 P-11 zinc finger U-box PF04564.10 OAI95875.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-UDP PF14569.1 OAI95875.1 - 4.3 7.1 6.7 0.53 10.0 1.1 2.0 2 0 0 2 2 2 0 Zinc-binding RING-finger Autotransporter PF03797.14 OAI95882.1 - 2.8e-26 92.4 4.5 4.4e-26 91.8 3.1 1.3 1 0 0 1 1 1 1 Autotransporter beta-domain Nuc_N PF14448.1 OAI95892.1 - 0.15 11.5 0.0 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Nuclease N terminal RVT_2 PF07727.9 OAI95898.1 - 2.7e-40 137.8 0.0 3.5e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3533 PF12051.3 OAI95901.1 - 0.033 12.9 0.5 0.047 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DDE_1 PF03184.14 OAI95904.1 - 0.075 12.1 0.0 0.94 8.5 0.0 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease zf-C3HC4_4 PF15227.1 OAI95912.1 - 1.4e-06 28.0 3.4 2.7e-06 27.1 2.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 OAI95912.1 - 1.7e-05 24.7 4.4 3.2e-05 23.8 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI95912.1 - 6.7e-05 22.4 4.0 0.00013 21.5 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI95912.1 - 0.00024 20.8 2.6 0.00048 19.8 1.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAI95912.1 - 0.001 18.7 4.0 0.0018 17.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI95912.1 - 0.0026 17.4 3.6 0.0053 16.4 2.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAI95912.1 - 0.02 14.6 4.6 0.046 13.4 3.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 OAI95912.1 - 0.18 11.5 1.9 0.4 10.5 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF572 PF04502.8 OAI95912.1 - 2.2 7.4 6.9 3.6 6.7 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) LysR_substrate PF03466.15 OAI95915.1 - 3e-33 114.7 1.9 4.1e-33 114.2 1.3 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.22 OAI95915.1 - 2.6e-21 75.1 0.3 2.6e-21 75.1 0.2 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_20 PF12840.2 OAI95915.1 - 0.0027 17.4 0.9 0.014 15.1 0.1 2.5 2 0 0 2 2 2 1 Helix-turn-helix domain MarR_2 PF12802.2 OAI95915.1 - 0.036 13.7 0.4 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.1 OAI95915.1 - 0.092 12.1 0.1 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GNAT_acetyltr_2 PF13718.1 OAI95923.1 - 2e-63 213.3 0.0 3.1e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.1 OAI95923.1 - 4.5e-24 84.4 0.2 2.5e-23 82.0 0.1 2.1 1 1 0 1 1 1 1 Possible tRNA binding domain MutS_V PF00488.16 OAI95924.1 - 0.00018 20.9 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V DUF770 PF05591.7 OAI95935.1 - 6.9e-13 48.4 0.0 8.6e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF770) DUF876 PF05936.7 OAI95936.1 - 7.6e-37 126.7 0.0 8.4e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF876) DUF2749 PF10907.3 OAI95947.1 - 0.6 10.0 3.6 0.92 9.4 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) DUF1180 PF06679.7 OAI95947.1 - 5.7 6.7 5.6 6.5 6.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Alpha_GJ PF03229.8 OAI95947.1 - 5.9 7.2 15.6 7 7.0 10.8 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J MSP1_C PF07462.6 OAI95947.1 - 8.8 4.5 10.5 8.9 4.5 7.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Vicilin_N PF04702.7 OAI95952.1 - 0.039 13.5 3.1 0.05 13.2 2.2 1.2 1 0 0 1 1 1 0 Vicilin N terminal region Phospholip_A2_3 PF09056.6 OAI95952.1 - 0.18 12.0 0.8 0.22 11.7 0.5 1.1 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 DUF4140 PF13600.1 OAI95952.1 - 0.57 10.6 7.9 0.76 10.2 5.5 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FlaF PF07309.6 OAI95952.1 - 0.65 9.8 4.5 0.9 9.4 3.1 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF Dak2 PF02734.12 OAI95952.1 - 4.1 7.0 6.6 0.94 9.1 2.1 1.6 1 1 1 2 2 2 0 DAK2 domain DivIC PF04977.10 OAI95952.1 - 7.1 6.1 7.7 10 5.7 5.3 1.2 1 0 0 1 1 1 0 Septum formation initiator Prp19 PF08606.6 OAI95955.1 - 9.6e-30 102.1 1.1 1.8e-29 101.2 0.7 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like DUF3450 PF11932.3 OAI95955.1 - 0.0069 15.6 0.3 0.0069 15.6 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 OAI95955.1 - 0.083 12.6 4.1 0.27 10.9 0.3 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Pex19 PF04614.7 OAI95955.1 - 0.084 12.4 0.2 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Pex19 protein family HisKA_3 PF07730.8 OAI95955.1 - 0.2 12.0 1.8 0.3 11.4 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase Cep57_CLD_2 PF14197.1 OAI95955.1 - 1.4 8.9 4.9 0.36 10.7 0.8 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Abhydrolase_6 PF12697.2 OAI95968.1 - 4.7e-07 29.9 0.4 6.9e-07 29.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI95968.1 - 6.6e-05 22.6 0.2 0.00017 21.3 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAI95968.1 - 0.0066 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 OAI95968.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.5 OAI95968.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3089 PF11288.3 OAI95968.1 - 0.088 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) LCAT PF02450.10 OAI95968.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 OAI95968.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Phage_integrase PF00589.17 OAI95970.1 - 4.8e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family Trypan_PARP PF05887.6 OAI95970.1 - 0.89 9.3 4.6 2.1 8.1 3.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sec5 PF15469.1 OAI95975.1 - 7.3e-56 188.7 0.4 1.1e-54 184.9 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAI95975.1 - 0.0035 17.1 0.1 0.013 15.2 0.0 2.1 1 1 0 1 1 1 1 Vps51/Vps67 HTH_9 PF08221.6 OAI95978.1 - 1.7e-19 69.3 0.1 2.8e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain Pyridox_ox_2 PF12900.2 OAI95980.1 - 6.4e-37 126.5 0.0 8.7e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.24 OAI95984.1 - 1.7e-11 43.7 0.0 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAI95984.1 - 9.3e-05 21.9 0.1 0.00011 21.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3175 PF11373.3 OAI95984.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) zf-C2H2 PF00096.21 OAI95986.1 - 0.0019 18.4 8.3 0.41 11.0 1.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI95986.1 - 0.027 14.7 7.0 1.6 9.2 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAI95986.1 - 0.047 13.6 4.3 0.73 9.8 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAI95986.1 - 0.26 11.6 8.9 11 6.5 0.2 3.3 2 1 0 2 2 2 0 Zinc-finger double domain zf-Di19 PF05605.7 OAI95986.1 - 0.34 11.0 6.4 0.78 9.9 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 OAI95986.1 - 0.52 10.4 5.3 23 5.1 3.7 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 OAI95986.1 - 1.8 8.8 4.4 13 6.1 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Retrotrans_gag PF03732.12 OAI95991.1 - 0.00038 20.4 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein PRC PF05239.11 OAI95994.1 - 0.023 14.5 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 PRC-barrel domain FHA PF00498.21 OAI96008.1 - 3.6e-05 23.7 0.0 0.00087 19.3 0.0 2.3 2 0 0 2 2 2 1 FHA domain Asp_protease_2 PF13650.1 OAI96009.1 - 8.9e-05 22.9 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI96009.1 - 0.004 17.0 0.0 0.0099 15.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI96009.1 - 0.027 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pil1 PF13805.1 OAI96015.1 - 2.5e-09 36.7 0.0 2.5e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Eisosome component PIL1 DUF4140 PF13600.1 OAI96015.1 - 7.8 7.0 8.8 12 6.4 0.2 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) NTP_transf_2 PF01909.18 OAI96019.1 - 0.00058 20.1 0.0 0.00098 19.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PilP PF04351.8 OAI96019.1 - 0.022 14.6 0.6 0.055 13.3 0.4 1.6 1 0 0 1 1 1 0 Pilus assembly protein, PilP GFA PF04828.9 OAI96026.1 - 0.065 13.1 0.2 0.065 13.1 0.1 3.3 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_CBB3 PF13442.1 OAI96026.1 - 0.49 10.5 2.7 0.53 10.4 0.1 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III DUF2072 PF09845.4 OAI96026.1 - 0.84 9.5 3.5 10 6.0 0.2 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Cytochrome_C7 PF14522.1 OAI96026.1 - 1.8 8.2 7.2 1.4 8.5 0.5 2.6 2 0 0 2 2 2 0 Cytochrome c7 zf-CCHC PF00098.18 OAI96031.1 - 3.3e-09 36.2 7.3 0.00016 21.4 1.7 3.1 2 0 0 2 2 2 2 Zinc knuckle gag_pre-integrs PF13976.1 OAI96031.1 - 1e-07 31.4 0.0 2.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAI96031.1 - 0.053 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI96031.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAI96031.1 - 6.2 6.5 6.1 7.9 6.2 0.6 2.6 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.6 OAI96033.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAI96033.1 - 7.3e-05 23.1 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAI96033.1 - 0.00012 21.8 2.5 0.00023 20.9 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI96033.1 - 0.00036 20.1 0.5 0.00036 20.1 0.3 2.0 2 0 0 2 2 2 1 Zinc knuckle gag-asp_proteas PF13975.1 OAI96033.1 - 0.0014 18.3 0.0 0.0039 16.9 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI96033.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC_3 PF13917.1 OAI96033.1 - 0.01 15.5 0.4 0.01 15.5 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI96033.1 - 0.12 12.0 0.2 0.23 11.1 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 OAI96033.1 - 0.2 11.6 0.4 0.35 10.7 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CDV3 PF15359.1 OAI96033.1 - 1.9 8.5 6.6 1.8 8.6 3.1 2.0 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Sec2p PF06428.6 OAI96077.1 - 0.071 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Abhydrolase_6 PF12697.2 OAI96084.1 - 2.7e-05 24.1 0.4 5.9e-05 23.0 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI96084.1 - 0.00026 20.7 0.2 0.00056 19.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family BLVR PF06375.6 OAI96087.1 - 0.19 11.5 15.4 0.54 10.0 10.7 1.7 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pox_Ag35 PF03286.9 OAI96087.1 - 1.7 8.0 14.0 3.8 6.9 9.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 OAI96087.1 - 6.7 7.0 13.5 3.8 7.8 7.6 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Protocadherin PF08374.6 OAI96087.1 - 9 5.8 11.9 15 5.1 8.2 1.3 1 0 0 1 1 1 0 Protocadherin Phage_int_SAM_1 PF02899.12 OAI96089.1 - 0.041 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DNA_pol_viral_C PF00336.13 OAI96090.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Uds1 PF15456.1 OAI96093.1 - 0.00091 19.2 1.5 0.0012 18.8 1.0 1.1 1 0 0 1 1 1 1 Up-regulated During Septation GAS PF13851.1 OAI96093.1 - 0.0028 16.8 1.7 0.0032 16.6 1.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 OAI96093.1 - 0.0038 17.0 3.2 0.051 13.4 2.2 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 OAI96093.1 - 0.0062 16.4 2.0 0.0077 16.0 1.4 1.2 1 0 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.3 OAI96093.1 - 0.0065 16.2 4.3 0.12 12.2 0.6 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding TelA PF05816.6 OAI96093.1 - 0.0072 15.0 1.0 0.011 14.4 0.7 1.3 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) bZIP_1 PF00170.16 OAI96093.1 - 0.0074 16.2 2.0 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 bZIP transcription factor DivIVA PF05103.8 OAI96093.1 - 0.011 15.7 0.9 0.016 15.2 0.6 1.2 1 0 0 1 1 1 0 DivIVA protein ADIP PF11559.3 OAI96093.1 - 0.014 15.2 1.8 0.084 12.7 0.1 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 OAI96093.1 - 0.016 14.7 1.1 0.15 11.5 0.8 1.8 1 1 1 2 2 2 0 Intermediate filament protein SSFA2_C PF14723.1 OAI96093.1 - 0.017 14.8 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus Lebercilin PF15619.1 OAI96093.1 - 0.019 14.4 1.8 0.022 14.1 1.3 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WD40_alt PF14077.1 OAI96093.1 - 0.019 14.5 0.3 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif Med9 PF07544.8 OAI96093.1 - 0.021 14.5 0.9 0.036 13.7 0.6 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4315 PF14193.1 OAI96093.1 - 0.023 14.6 0.2 3.6 7.5 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4315) Flagellin_C PF00700.16 OAI96093.1 - 0.028 14.5 2.1 0.045 13.9 0.8 1.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region DNA_gyraseB PF00204.20 OAI96093.1 - 0.036 13.2 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 DNA gyrase B BLOC1_2 PF10046.4 OAI96093.1 - 0.045 13.8 0.7 0.15 12.2 0.5 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 OAI96093.1 - 0.066 13.5 3.5 2.7 8.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 OAI96093.1 - 0.11 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 OAI96093.1 - 0.11 11.9 0.3 2.9 7.4 0.0 2.2 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.7 OAI96093.1 - 0.11 12.7 0.7 1.2 9.4 0.5 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DMPK_coil PF08826.5 OAI96093.1 - 0.12 12.3 1.8 0.2 11.6 0.1 2.1 1 1 1 2 2 2 0 DMPK coiled coil domain like Reo_sigmaC PF04582.7 OAI96093.1 - 0.12 11.4 3.0 0.27 10.3 2.0 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 OAI96093.1 - 0.14 12.1 3.2 1.7 8.7 0.5 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil Mto2_bdg PF12808.2 OAI96093.1 - 0.84 9.7 4.9 0.36 10.9 0.7 2.0 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Peptidase_S10 PF00450.17 OAI96097.1 - 1.5e-07 30.9 0.0 1.7e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Uds1 PF15456.1 OAI96102.1 - 5.3e-05 23.2 1.7 6.3e-05 22.9 1.2 1.1 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 OAI96102.1 - 0.00012 21.7 0.2 0.00015 21.4 0.2 1.1 1 0 0 1 1 1 1 IncA protein MAD PF05557.8 OAI96102.1 - 0.0012 17.0 1.8 0.0015 16.7 1.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein GAS PF13851.1 OAI96102.1 - 0.0014 17.8 3.1 0.0016 17.6 2.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF2353 PF09789.4 OAI96102.1 - 0.0023 17.2 1.6 0.0028 16.9 1.1 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Tropomyosin_1 PF12718.2 OAI96102.1 - 0.0035 17.1 3.6 0.0043 16.8 2.5 1.1 1 0 0 1 1 1 1 Tropomyosin like WD40_alt PF14077.1 OAI96102.1 - 0.012 15.2 2.4 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2968 PF11180.3 OAI96102.1 - 0.019 14.3 0.2 0.081 12.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF972 PF06156.8 OAI96102.1 - 0.019 15.3 1.0 0.099 12.9 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 OAI96102.1 - 0.031 14.0 3.7 0.057 13.1 2.6 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DMPK_coil PF08826.5 OAI96102.1 - 0.038 13.8 0.8 0.038 13.8 0.6 2.2 1 1 0 2 2 2 0 DMPK coiled coil domain like Sirohm_synth_C PF14823.1 OAI96102.1 - 0.038 13.2 0.8 0.059 12.6 0.1 1.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DivIC PF04977.10 OAI96102.1 - 0.043 13.2 2.2 2.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.13 OAI96102.1 - 0.049 13.6 0.9 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4391 PF14335.1 OAI96102.1 - 0.05 12.9 0.6 0.057 12.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF641 PF04859.7 OAI96102.1 - 0.062 13.0 0.3 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Cob_adeno_trans PF01923.13 OAI96102.1 - 0.067 12.9 0.1 0.087 12.6 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase bZIP_1 PF00170.16 OAI96102.1 - 0.076 12.9 4.4 0.96 9.4 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 OAI96102.1 - 0.1 12.9 4.2 0.64 10.3 2.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ADIP PF11559.3 OAI96102.1 - 0.15 11.9 4.2 2.8 7.8 0.3 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 OAI96102.1 - 0.16 11.1 0.2 0.58 9.2 0.1 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 OAI96102.1 - 0.18 11.8 6.7 2.5 8.1 0.7 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil DivIVA PF05103.8 OAI96102.1 - 0.18 11.8 1.9 0.29 11.1 1.3 1.3 1 1 0 1 1 1 0 DivIVA protein Prefoldin_2 PF01920.15 OAI96102.1 - 0.18 11.5 1.6 1.3 8.7 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 OAI96102.1 - 0.2 11.1 6.1 0.73 9.2 0.4 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 Spectrin PF00435.16 OAI96102.1 - 0.22 11.8 2.0 10 6.4 0.1 2.1 1 1 1 2 2 2 0 Spectrin repeat CENP-F_leu_zip PF10473.4 OAI96102.1 - 0.24 11.2 4.4 1.6 8.6 0.3 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 OAI96102.1 - 0.3 10.9 11.0 1.2 8.9 1.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3373 PF11853.3 OAI96102.1 - 0.3 9.5 3.5 0.54 8.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 OAI96102.1 - 0.3 11.1 7.6 2.1 8.4 0.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.1 OAI96102.1 - 0.41 10.0 6.0 0.75 9.1 4.2 1.4 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_2 PF07716.10 OAI96102.1 - 0.84 9.4 4.9 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pox_A_type_inc PF04508.7 OAI96102.1 - 1.4 8.9 4.7 12 5.9 0.1 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4315 PF14193.1 OAI96102.1 - 1.5 8.7 6.6 7.6 6.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) RCC1 PF00415.13 OAI96114.1 - 0.16 12.2 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Apolipoprotein PF01442.13 OAI96118.1 - 0.15 11.5 3.6 1.6 8.2 2.5 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAI96118.1 - 7 7.1 29.8 13 6.2 5.7 4.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Peptidase_S64 PF08192.6 OAI96118.1 - 7.6 4.7 18.9 10 4.2 13.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Abhydrolase_6 PF12697.2 OAI96120.1 - 5.9e-09 36.1 2.0 7.7e-09 35.7 0.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI96120.1 - 0.11 12.2 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phage_integrase PF00589.17 OAI96126.1 - 0.004 16.8 0.0 0.0085 15.7 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family SWIM PF04434.12 OAI96129.1 - 2.7e-05 23.5 0.5 5.2e-05 22.6 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger AMP-binding PF00501.23 OAI96131.1 - 9e-22 77.0 0.3 2.3e-21 75.6 0.2 1.5 1 1 0 1 1 1 1 AMP-binding enzyme YqjK PF13997.1 OAI96131.1 - 0.059 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 YqjK-like protein Thr_synth_N PF14821.1 OAI96131.1 - 0.083 12.9 0.0 37 4.4 0.0 3.4 3 0 0 3 3 3 0 Threonine synthase N terminus WD40 PF00400.27 OAI96134.1 - 1e-10 41.0 0.1 1.8e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat TPR_11 PF13414.1 OAI96137.1 - 0.034 13.7 0.3 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat RasGAP_C PF03836.10 OAI96137.1 - 0.2 11.3 0.2 0.44 10.2 0.2 1.5 1 0 0 1 1 1 0 RasGAP C-terminus DUF2235 PF09994.4 OAI96146.1 - 5.7e-17 61.9 0.0 2.8e-09 36.7 0.0 3.1 2 1 0 3 3 3 3 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-trcl PF13451.1 OAI96149.1 - 2.1 8.0 4.9 4.5 6.9 0.3 2.3 2 0 0 2 2 2 0 Probable zinc-binding domain Pantoate_ligase PF02569.10 OAI96156.1 - 6.5e-104 346.6 0.0 7.3e-104 346.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase PALP PF00291.20 OAI96159.1 - 4e-49 167.5 1.5 9.4e-49 166.2 1.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.10 OAI96159.1 - 0.04 13.5 0.1 0.088 12.4 0.1 1.6 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein rve PF00665.21 OAI96164.1 - 4.9e-25 87.9 0.0 1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAI96164.1 - 6e-10 38.6 0.1 1.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAI96164.1 - 1.1e-08 34.5 0.0 2.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI96164.1 - 5.3e-06 26.0 9.5 0.0053 16.6 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle UBN2 PF14223.1 OAI96164.1 - 2.6e-05 23.9 0.1 6.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.1 OAI96164.1 - 0.0013 18.2 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_3 PF13358.1 OAI96164.1 - 0.011 15.5 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-CCHC_3 PF13917.1 OAI96164.1 - 0.054 13.2 9.9 0.087 12.5 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAI96164.1 - 0.42 10.1 9.8 1.7 8.1 1.1 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI96164.1 - 3.8 7.2 9.6 3.9 7.2 1.1 2.6 2 0 0 2 2 2 0 Zinc knuckle AAA_35 PF14516.1 OAI96166.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Pkinase PF00069.20 OAI96171.1 - 6.2e-06 25.5 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 OAI96171.1 - 6.6e-05 22.0 0.3 0.00028 20.0 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAI96171.1 - 0.007 16.1 0.5 0.016 14.9 0.4 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 OAI96171.1 - 0.027 13.5 0.0 0.079 12.0 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Med3 PF11593.3 OAI96177.1 - 0.96 8.6 14.5 1.3 8.2 10.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-CCHC PF00098.18 OAI96180.1 - 9.7e-06 25.2 1.2 1.5e-05 24.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAI96180.1 - 2.6e-05 24.2 0.2 0.00042 20.3 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC_6 PF15288.1 OAI96180.1 - 0.036 13.7 0.2 0.095 12.3 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 OAI96180.1 - 0.084 12.3 1.2 0.15 11.5 0.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 OAI96180.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 OAI96180.1 - 0.11 12.4 1.2 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RTC4 PF14474.1 OAI96184.1 - 2.2e-08 34.0 0.0 3.2e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain ProSAAS PF07259.7 OAI96184.1 - 0.091 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ProSAAS precursor DUF1146 PF06612.6 OAI96190.1 - 3.2 7.7 5.1 20 5.1 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1146) FliW PF02623.10 OAI96198.1 - 0.007 15.9 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 FliW protein Asp PF00026.18 OAI96200.1 - 3.8e-11 42.8 0.1 6.2e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF550 PF04447.7 OAI96204.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF550) RVT_1 PF00078.22 OAI96207.1 - 2e-22 79.6 0.2 4.3e-22 78.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAI96207.1 - 9.2e-09 35.3 0.0 1.6e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAI96207.1 - 0.00015 22.1 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI96207.1 - 0.03 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pkinase_Tyr PF07714.12 OAI96212.1 - 7.3e-06 25.2 0.0 9.4e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 OAI96212.1 - 7.4e-05 22.0 0.0 9.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain YrhC PF14143.1 OAI96216.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 YrhC-like protein Beta-Casp PF10996.3 OAI96223.1 - 5.9e-13 48.8 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Beta-Casp domain FHA PF00498.21 OAI96238.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 FHA domain TFIIA PF03153.8 OAI96239.1 - 1.4 8.7 8.8 3.1 7.5 6.1 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mhr1 PF12829.2 OAI96243.1 - 0.48 10.2 4.7 0.26 11.1 0.7 2.2 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination RNaseH_C PF09293.5 OAI96243.1 - 0.52 10.2 7.7 1.6 8.6 0.8 2.6 1 1 1 2 2 2 0 T4 RNase H, C terminal DUF1635 PF07795.6 OAI96243.1 - 1.1 8.5 14.1 2.2 7.6 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PIF1 PF05970.9 OAI96245.1 - 1.2e-21 77.1 0.0 2.2e-21 76.2 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase Isochorismatase PF00857.15 OAI96250.1 - 3.6e-22 79.1 0.0 4.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family RVT_3 PF13456.1 OAI96251.1 - 0.1 12.4 0.4 0.3 10.9 0.2 1.8 1 1 1 2 2 2 0 Reverse transcriptase-like HTH_22 PF13309.1 OAI96251.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 HTH domain FUSC PF04632.7 OAI96251.1 - 0.14 10.5 7.3 0.15 10.4 5.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aminotran_4 PF01063.14 OAI96252.1 - 8.4e-20 71.2 0.0 1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class IV zf-CCHC PF00098.18 OAI96255.1 - 5.5e-05 22.8 2.4 8.5e-05 22.3 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAI96255.1 - 0.00022 20.8 0.7 0.00046 19.7 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAI96255.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 OAI96255.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle TMEM237 PF15383.1 OAI96255.1 - 0.044 12.9 0.4 0.089 11.9 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 zf-CCHC_2 PF13696.1 OAI96255.1 - 0.049 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI96255.1 - 0.12 12.0 0.3 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 OAI96255.1 - 1.2 9.1 3.5 0.48 10.3 0.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Pkinase PF00069.20 OAI96264.1 - 2.2e-48 164.7 0.0 4.9e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96264.1 - 1.2e-29 103.1 0.0 2.1e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF812 PF05667.6 OAI96264.1 - 0.00036 19.1 14.9 0.00053 18.6 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IncA PF04156.9 OAI96264.1 - 0.00037 20.1 38.8 0.039 13.5 9.7 2.3 1 1 1 2 2 2 2 IncA protein Kdo PF06293.9 OAI96264.1 - 0.00037 19.6 0.0 0.00088 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAI96264.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF641 PF04859.7 OAI96264.1 - 0.0016 18.1 4.2 0.0016 18.1 2.9 2.5 1 1 2 3 3 3 1 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 OAI96264.1 - 0.003 16.1 16.0 0.004 15.6 11.1 1.1 1 0 0 1 1 1 1 AAA domain Sec8_exocyst PF04048.9 OAI96264.1 - 0.0033 17.0 21.1 0.1 12.2 2.4 4.2 1 1 3 4 4 4 3 Sec8 exocyst complex component specific domain Atg14 PF10186.4 OAI96264.1 - 0.0062 15.5 29.6 0.0091 14.9 8.5 2.2 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 OAI96264.1 - 0.012 15.4 11.5 0.021 14.6 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 OAI96264.1 - 0.045 13.5 31.7 0.13 12.1 10.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin_2 PF01920.15 OAI96264.1 - 0.15 11.8 18.4 1.2 8.8 0.9 3.4 2 1 1 3 3 3 0 Prefoldin subunit APH PF01636.18 OAI96264.1 - 0.2 11.3 0.0 0.2 11.3 0.0 3.2 2 1 1 3 3 2 0 Phosphotransferase enzyme family WEMBL PF05701.6 OAI96264.1 - 0.25 9.7 28.9 0.62 8.4 20.1 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light MHC_II_alpha PF00993.15 OAI96264.1 - 0.3 10.6 0.7 9.2 5.9 0.1 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain TPR_MLP1_2 PF07926.7 OAI96264.1 - 0.3 10.8 32.1 0.74 9.5 5.7 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.5 OAI96264.1 - 0.39 10.6 32.1 0.3 11.0 2.3 3.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) CCDC144C PF14915.1 OAI96264.1 - 0.43 9.4 28.5 0.63 8.9 19.7 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Spc7 PF08317.6 OAI96264.1 - 0.5 8.9 24.5 0.83 8.2 8.2 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3135 PF11333.3 OAI96264.1 - 0.54 10.4 6.7 4.2 7.5 1.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) E2R135 PF11570.3 OAI96264.1 - 0.55 10.3 9.7 0.22 11.5 4.4 2.2 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 ERM PF00769.14 OAI96264.1 - 0.59 9.6 29.7 13 5.2 19.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2951 PF11166.3 OAI96264.1 - 0.83 9.5 2.4 1.6 8.6 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) Fib_alpha PF08702.5 OAI96264.1 - 1.8 8.6 17.9 0.74 9.9 2.6 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 OAI96264.1 - 1.9 7.6 19.0 1.7 7.7 4.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 OAI96264.1 - 2 5.6 31.3 3.6 4.7 21.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF342 PF03961.8 OAI96264.1 - 3.4 5.9 14.8 1.7 6.9 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4201 PF13870.1 OAI96264.1 - 3.6 6.9 15.1 1.4 8.2 4.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) APG6 PF04111.7 OAI96264.1 - 4.9 6.1 28.2 1.3 7.9 11.9 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 RmuC PF02646.11 OAI96264.1 - 6.5 5.4 18.5 0.64 8.8 1.5 3.0 1 1 0 2 2 2 0 RmuC family TMF_DNA_bd PF12329.3 OAI96264.1 - 6.7 6.6 29.0 0.019 14.7 4.2 3.5 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 OAI96264.1 - 7.3 6.2 28.3 5.5 6.6 5.4 3.2 1 1 2 3 3 3 0 Mnd1 family Herpes_UL32 PF06070.6 OAI96272.1 - 2.1 6.7 14.7 2.9 6.2 10.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 KAR9 PF08580.5 OAI96272.1 - 6.1 4.9 10.5 6.3 4.9 7.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-CCHC_4 PF14392.1 OAI96275.1 - 2.7 7.7 4.5 12 5.7 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle NPR3 PF03666.8 OAI96279.1 - 3.1e-30 105.0 3.9 7e-29 100.6 2.5 2.5 2 1 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.18 OAI96285.1 - 0.042 12.5 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain DUF605 PF04652.11 OAI96285.1 - 1.7 7.9 10.9 1.9 7.8 7.5 1.1 1 0 0 1 1 1 0 Vta1 like Asp_protease_2 PF13650.1 OAI96288.1 - 1.8e-05 25.1 0.0 4.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI96288.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI96288.1 - 0.038 13.8 0.1 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Flavoprotein PF02441.14 OAI96292.1 - 0.006 16.2 0.3 0.0075 15.9 0.2 1.3 1 0 0 1 1 1 1 Flavoprotein DUF566 PF04484.7 OAI96292.1 - 0.86 9.0 6.5 0.97 8.8 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cupin_4 PF08007.7 OAI96293.1 - 1.9e-47 162.0 0.1 2.4e-47 161.7 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 OAI96293.1 - 1e-11 44.8 0.2 5e-10 39.3 0.1 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 OAI96293.1 - 0.032 13.7 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Retrotrans_gag PF03732.12 OAI96314.1 - 0.0054 16.7 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI96314.1 - 0.036 13.9 2.1 0.055 13.4 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle MdcG PF10620.4 OAI96319.1 - 0.011 15.2 0.3 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG eIF3_subunit PF08597.5 OAI96321.1 - 7.5e-44 150.1 27.3 8.9e-44 149.8 18.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.1 OAI96321.1 - 0.031 14.5 39.1 0.11 12.8 6.5 3.5 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Merozoite_SPAM PF07133.6 OAI96321.1 - 0.33 10.8 20.9 0.016 15.1 10.0 1.8 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) DUF2235 PF09994.4 OAI96323.1 - 1.4e-45 155.8 0.0 1.2e-27 96.9 0.0 3.3 2 1 1 3 3 3 3 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.20 OAI96323.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Lipase3_N PF03893.11 OAI96327.1 - 0.95 9.3 4.0 0.24 11.2 0.2 1.9 2 0 0 2 2 2 0 Lipase 3 N-terminal region WD40 PF00400.27 OAI96338.1 - 2.1e-82 268.3 25.4 2.2e-12 46.3 0.0 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 OAI96338.1 - 7.2e-06 25.9 0.1 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 OAI96338.1 - 0.00021 19.6 7.2 0.56 8.2 0.1 4.7 4 1 1 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 OAI96338.1 - 0.00029 20.6 0.0 0.0063 16.2 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 OAI96338.1 - 0.0018 17.5 1.8 0.2 11.0 0.1 3.0 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 OAI96338.1 - 0.0033 16.2 6.0 0.077 11.7 0.1 4.0 3 2 0 4 4 4 1 Nup133 N terminal like IKI3 PF04762.7 OAI96338.1 - 0.14 9.9 0.3 0.3 8.8 0.0 1.7 2 0 0 2 2 2 0 IKI3 family Nbas_N PF15492.1 OAI96338.1 - 0.14 11.2 2.1 5.4 6.0 0.0 3.0 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal FHA PF00498.21 OAI96344.1 - 0.00056 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Bac_luciferase PF00296.15 OAI96361.1 - 0.16 11.0 0.9 0.19 10.8 0.6 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase LysR_substrate PF03466.15 OAI96372.1 - 1.7e-28 99.1 0.1 1.9e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 LysR substrate binding domain LysR_substrate PF03466.15 OAI96373.1 - 8.8e-39 132.7 1.3 1.5e-38 132.0 0.9 1.3 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.22 OAI96373.1 - 7.4e-22 76.8 2.0 1.3e-21 76.0 1.4 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family HTH_8 PF02954.14 OAI96373.1 - 0.047 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family MarR_2 PF12802.2 OAI96373.1 - 0.072 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 MarR family HTH_5 PF01022.15 OAI96373.1 - 0.1 12.2 0.9 0.23 11.1 0.2 1.9 2 1 0 2 2 2 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 OAI96373.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.1 OAI96373.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain AMP-binding PF00501.23 OAI96379.1 - 1.1e-80 271.1 0.0 1.4e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 OAI96379.1 - 2.1e-19 69.4 0.0 2.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain HTH_38 PF13936.1 OAI96379.1 - 0.088 12.3 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Rhamnogal_lyase PF06045.6 OAI96379.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family Flo11 PF10182.4 OAI96379.1 - 0.11 12.0 0.1 17 4.9 0.0 2.8 3 0 0 3 3 3 0 Flo11 domain TetR_N PF00440.18 OAI96379.1 - 0.13 11.8 0.2 8.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family RVT_1 PF00078.22 OAI96395.1 - 3.4e-18 65.7 0.0 7.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma70_r1_2 PF00140.15 OAI96399.1 - 0.012 15.2 0.2 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 HpaP PF09483.5 OAI96399.1 - 0.61 10.0 11.6 0.81 9.6 8.1 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) CIA30 PF08547.7 OAI96423.1 - 1.5e-18 67.1 0.0 3.3e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) gag-asp_proteas PF13975.1 OAI96431.1 - 5.3e-09 35.7 0.3 1.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI96431.1 - 1.7e-06 28.4 0.0 1.1e-05 25.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 OAI96431.1 - 7.6e-05 22.6 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI96431.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI96431.1 - 0.0015 18.4 0.2 0.012 15.5 0.0 2.4 2 2 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 OAI96431.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Retrotrans_gag PF03732.12 OAI96432.1 - 0.055 13.5 1.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3138 PF11336.3 OAI96432.1 - 0.4 8.8 3.5 0.55 8.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Enoyl_reductase PF12241.3 OAI96435.1 - 0.094 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Bile_Hydr_Trans PF04775.9 OAI96435.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region TPR_MLP1_2 PF07926.7 OAI96444.1 - 0.0019 17.9 14.9 0.0023 17.6 5.9 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein OEP PF02321.13 OAI96444.1 - 0.018 14.6 8.1 0.022 14.3 5.6 1.3 1 0 0 1 1 1 0 Outer membrane efflux protein FliJ PF02050.11 OAI96444.1 - 0.033 14.2 12.4 0.055 13.5 6.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein GBP_C PF02841.9 OAI96444.1 - 0.035 13.3 11.9 0.052 12.7 8.3 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain WEMBL PF05701.6 OAI96444.1 - 0.039 12.4 16.3 0.14 10.6 2.8 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light APG6 PF04111.7 OAI96444.1 - 0.11 11.5 10.8 0.13 11.2 7.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Rootletin PF15035.1 OAI96444.1 - 0.12 12.3 13.0 0.17 11.8 9.0 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 OAI96444.1 - 0.14 11.7 12.2 0.39 10.2 8.5 1.6 1 1 0 1 1 1 0 IncA protein IFT57 PF10498.4 OAI96444.1 - 0.2 10.3 5.3 0.28 9.8 3.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Laminin_II PF06009.7 OAI96444.1 - 0.21 11.3 10.1 0.58 9.9 0.2 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF342 PF03961.8 OAI96444.1 - 0.28 9.5 3.4 0.3 9.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3826 PF12875.2 OAI96444.1 - 0.32 10.6 6.5 1.4 8.5 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) Spc7 PF08317.6 OAI96444.1 - 0.78 8.3 8.4 1 7.9 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.7 OAI96444.1 - 0.82 8.0 9.2 0.92 7.8 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBPIP PF07106.8 OAI96444.1 - 1.3 8.5 8.7 1.9 7.9 6.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2951 PF11166.3 OAI96444.1 - 1.4 8.7 4.3 3.1 7.7 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) LMBR1 PF04791.11 OAI96444.1 - 2.9 6.3 4.1 3.9 5.9 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CENP-F_leu_zip PF10473.4 OAI96444.1 - 2.9 7.7 14.2 16 5.3 9.9 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 OAI96444.1 - 3.2 7.7 15.6 0.69 9.8 4.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Peptidase_S64 PF08192.6 OAI96444.1 - 4.6 5.4 9.5 5.3 5.2 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 EMP24_GP25L PF01105.19 OAI96444.1 - 5.5 6.6 6.6 9.6 5.8 0.5 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF607 PF04678.8 OAI96444.1 - 6.8 6.5 7.7 1.5 8.7 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Atg14 PF10186.4 OAI96444.1 - 7.7 5.3 8.8 12 4.7 6.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 OAI96444.1 - 7.8 6.3 13.0 18 5.2 0.2 2.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SpoIIIAH PF12685.2 OAI96444.1 - 8.4 5.8 14.2 10 5.5 9.8 1.3 1 1 0 1 1 1 0 SpoIIIAH-like protein RICH PF05062.7 OAI96444.1 - 9.2 6.4 7.5 17 5.6 2.6 2.7 1 1 0 2 2 2 0 RICH domain HAUS-augmin3 PF14932.1 OAI96444.1 - 9.6 5.2 12.5 18 4.4 8.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Pkinase PF00069.20 OAI96450.1 - 1.4e-40 139.1 0.0 1.7e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96450.1 - 1.3e-16 60.5 0.0 2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI96450.1 - 2.4e-07 30.0 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAI96450.1 - 0.00043 19.3 0.0 0.00072 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BLVR PF06375.6 OAI96451.1 - 0.042 13.6 10.9 0.096 12.5 7.6 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Vfa1 PF08432.5 OAI96451.1 - 0.076 13.0 6.3 0.13 12.2 4.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 OAI96451.1 - 0.19 12.0 9.9 0.53 10.6 6.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3_subunit PF08597.5 OAI96451.1 - 0.49 9.9 12.8 0.97 8.9 8.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_C37 PF05416.7 OAI96451.1 - 1.2 7.3 3.7 1.8 6.7 2.5 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Pox_Ag35 PF03286.9 OAI96451.1 - 1.2 8.6 10.5 2.5 7.5 7.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein rve PF00665.21 OAI96457.1 - 1.8e-16 60.3 0.0 3.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAI96457.1 - 2.6e-05 23.7 0.9 4.8e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 OAI96462.1 - 3.7e-08 33.0 0.0 6.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI96462.1 - 2.5e-06 27.9 0.1 3.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI96462.1 - 4.2e-06 26.6 0.0 5.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI96462.1 - 0.00033 20.2 0.0 0.00038 20.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF4310 PF14187.1 OAI96462.1 - 0.013 14.9 0.1 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Peptidase_A2E PF12382.3 OAI96462.1 - 0.023 14.4 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon peptidase RCC1_2 PF13540.1 OAI96465.1 - 7.1e-10 38.2 4.3 2.9e-07 29.9 0.1 3.1 2 2 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 OAI96465.1 - 9e-10 38.6 0.2 0.00024 21.2 0.0 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat GluR_Homer-bdg PF10606.4 OAI96466.1 - 0.17 11.8 2.0 0.33 10.8 1.4 1.7 1 1 0 1 1 1 0 Homer-binding domain of metabotropic glutamate receptor NPFF PF15085.1 OAI96467.1 - 0.057 13.7 0.9 0.083 13.1 0.6 1.3 1 0 0 1 1 1 0 Neuropeptide FF TPR_21 PF09976.4 OAI96467.1 - 0.22 11.4 3.6 0.59 10.0 2.5 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF2673 PF10880.3 OAI96472.1 - 0.24 11.4 1.0 0.44 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) ALS2CR8 PF15299.1 OAI96487.1 - 0.24 10.9 2.8 5.7 6.4 0.1 2.3 2 0 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Colicin_D PF11429.3 OAI96494.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Colicin D DUF2946 PF11162.3 OAI96501.1 - 0.049 13.8 0.1 0.049 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) FHA PF00498.21 OAI96504.1 - 5.8e-05 23.1 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain SAG PF04092.8 OAI96504.1 - 1.1 9.7 6.9 4.4 7.7 0.0 2.7 2 1 1 3 3 3 0 SRS domain Dimer_Tnp_hAT PF05699.9 OAI96506.1 - 6.9e-23 80.0 0.2 2.5e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAI96506.1 - 1e-05 25.1 0.1 2.4e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger DUF2155 PF09923.4 OAI96506.1 - 0.022 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) DIOX_N PF14226.1 OAI96506.1 - 0.043 14.3 0.0 82 3.7 0.0 4.0 3 1 1 4 4 4 0 non-haem dioxygenase in morphine synthesis N-terminal rve PF00665.21 OAI96508.1 - 2.8e-05 24.2 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain BCLP PF12304.3 OAI96510.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-casein like protein Cg6151-P PF10233.4 OAI96511.1 - 0.059 13.3 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P CactinC_cactus PF09732.4 OAI96511.1 - 0.094 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein WD40 PF00400.27 OAI96516.1 - 1e-28 98.0 3.0 3.3e-07 29.9 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat eIF2A PF08662.6 OAI96516.1 - 1.1e-05 25.1 0.1 0.0059 16.3 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A rve PF00665.21 OAI96521.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ribosom_S12_S23 PF00164.20 OAI96526.1 - 1.3e-17 63.3 0.1 1.4e-17 63.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ADH_zinc_N PF00107.21 OAI96528.1 - 1.5e-16 60.0 0.4 2.7e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAI96528.1 - 1.2e-15 58.5 0.1 3.3e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAI96528.1 - 7.6e-08 32.0 0.0 3.6e-07 29.9 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAI96528.1 - 0.016 14.7 0.2 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAGK_cat PF00781.19 OAI96528.1 - 0.047 13.1 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain CMAS PF02353.15 OAI96528.1 - 0.055 12.5 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase AlaDh_PNT_C PF01262.16 OAI96528.1 - 0.058 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DDE_Tnp_4 PF13359.1 OAI96534.1 - 5e-19 68.4 0.0 8.8e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 OAI96534.1 - 0.00016 21.1 0.0 0.00052 19.5 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI96534.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.1 OAI96534.1 - 0.0047 16.5 0.4 0.03 13.9 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_36 PF13730.1 OAI96534.1 - 0.03 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain VHP PF02209.14 OAI96534.1 - 0.041 13.5 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain MarR PF01047.17 OAI96534.1 - 0.057 13.1 0.4 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 MarR family Plant_tran PF04827.9 OAI96534.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein Sigma70_r4 PF04545.11 OAI96534.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.1 OAI96534.1 - 0.11 11.6 0.7 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 OAI96534.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain Baculo_PEP_C PF04513.7 OAI96537.1 - 0.035 13.9 1.6 0.12 12.2 0.4 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.1 OAI96537.1 - 0.037 14.1 5.0 0.19 11.9 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Sigma54_CBD PF04963.8 OAI96537.1 - 0.079 12.3 0.5 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF601 PF04642.7 OAI96537.1 - 0.097 12.0 4.9 0.11 11.8 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DUF3383 PF11863.3 OAI96537.1 - 0.12 11.0 1.9 0.14 10.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) Succ_DH_flav_C PF02910.15 OAI96537.1 - 0.16 11.8 1.0 0.42 10.4 0.8 1.7 1 1 1 2 2 2 0 Fumarate reductase flavoprotein C-term Nnf1 PF03980.9 OAI96537.1 - 0.28 11.1 3.2 0.66 10.0 0.2 2.0 1 1 1 2 2 2 0 Nnf1 FliT PF05400.8 OAI96537.1 - 0.37 11.2 2.4 0.36 11.2 0.8 1.6 1 1 1 2 2 2 0 Flagellar protein FliT Transposase_21 PF02992.9 OAI96541.1 - 9e-23 80.5 0.0 1.4e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAI96541.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1586 PF07625.6 OAI96544.1 - 0.039 13.7 0.2 0.25 11.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) HCMV_UL139 PF12507.3 OAI96544.1 - 0.16 12.1 1.2 0.23 11.5 0.8 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein SR-25 PF10500.4 OAI96548.1 - 0.0078 15.7 8.8 0.0078 15.7 6.1 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Flocculin PF00624.13 OAI96548.1 - 0.78 9.6 9.1 0.17 11.7 2.1 2.2 2 0 0 2 2 2 0 Flocculin repeat Sec10 PF07393.6 OAI96548.1 - 1.4 6.9 4.8 2.1 6.4 3.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Myb_DNA-bind_3 PF12776.2 OAI96552.1 - 2.1e-12 47.5 0.5 3.4e-12 46.8 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAI96552.1 - 4.1e-05 23.6 2.0 0.00016 21.7 0.1 2.2 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Nop14 PF04147.7 OAI96552.1 - 0.0092 13.9 12.4 0.011 13.7 8.6 1.1 1 0 0 1 1 1 1 Nop14-like family Myb_DNA-binding PF00249.26 OAI96552.1 - 0.069 13.2 1.3 0.59 10.2 0.9 2.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain BUD22 PF09073.5 OAI96552.1 - 0.083 11.9 13.6 0.11 11.5 9.4 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 OAI96552.1 - 0.27 9.6 8.4 0.35 9.2 5.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF3827 PF12877.2 OAI96552.1 - 0.59 8.1 2.9 0.71 7.9 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sigma70_ner PF04546.8 OAI96552.1 - 0.93 9.0 6.5 1.5 8.4 4.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 OAI96552.1 - 4 6.4 15.2 5.9 5.9 10.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 OAI96552.1 - 4.6 6.4 10.5 6 6.0 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein RVT_1 PF00078.22 OAI96554.1 - 3e-22 79.0 0.0 4.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI96554.1 - 9.2e-18 64.8 0.0 1.9e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 RNase H Tim44 PF04280.10 OAI96559.1 - 1.3e-07 31.7 1.3 1e-06 28.7 0.0 2.6 2 0 0 2 2 2 1 Tim44-like domain Mito_fiss_reg PF05308.6 OAI96559.1 - 0.00037 19.9 4.8 0.00037 19.9 3.4 2.2 2 0 0 2 2 2 1 Mitochondrial fission regulator U79_P34 PF03064.11 OAI96559.1 - 0.0063 16.0 4.0 0.0063 16.0 2.8 2.0 2 0 0 2 2 2 1 HSV U79 / HCMV P34 API5 PF05918.6 OAI96559.1 - 0.91 7.9 6.0 1.7 7.0 4.2 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pex14_N PF04695.8 OAI96559.1 - 1.4 8.9 16.8 2.5 8.1 4.2 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2763 PF10961.3 OAI96559.1 - 3.4 8.1 6.5 9.8 6.6 4.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF3209 PF11483.3 OAI96559.1 - 8.1 6.8 9.2 7.6 6.8 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) RabGAP-TBC PF00566.13 OAI96576.1 - 7.1e-28 97.5 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Helicase_RecD PF05127.9 OAI96591.1 - 1.3e-28 99.8 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 OAI96591.1 - 0.0038 17.3 0.2 0.039 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain Ocular_alb PF02101.10 OAI96591.1 - 0.015 13.9 0.2 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Ocular albinism type 1 protein AAA_30 PF13604.1 OAI96591.1 - 0.11 12.0 0.1 9.5 5.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 OAI96594.1 - 0.00038 20.6 0.1 0.0012 19.0 0.1 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI96594.1 - 0.0077 16.4 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger FHA PF00498.21 OAI96605.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain Abhydrolase_6 PF12697.2 OAI96607.1 - 2.3e-12 47.2 0.5 3.4e-12 46.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI96607.1 - 4.1e-07 29.8 0.1 8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAI96607.1 - 0.0001 21.2 0.0 0.00024 20.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.16 OAI96607.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.6 OAI96607.1 - 0.042 12.9 0.0 0.084 11.9 0.0 1.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) UCR_UQCRX_QCR9 PF05365.7 OAI96608.1 - 0.16 11.6 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ketoacyl-synt_C PF02801.17 OAI96611.1 - 9.2e-16 57.7 0.4 9.6e-16 57.7 0.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Peptidase_M16 PF00675.15 OAI96614.1 - 3.3e-23 82.0 0.0 4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAI96614.1 - 5.7e-07 29.3 0.1 4.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Transaldolase PF00923.14 OAI96614.1 - 0.015 14.3 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Transaldolase HlyD_3 PF13437.1 OAI96615.1 - 9.4e-16 58.0 0.1 3.1e-12 46.7 0.0 3.2 3 1 0 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAI96615.1 - 1.7e-12 46.8 2.1 2.5e-05 23.8 0.1 3.3 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_2 PF12700.2 OAI96615.1 - 3.8e-06 26.2 0.0 0.0023 17.1 0.0 2.1 1 1 0 2 2 2 2 HlyD family secretion protein Biotin_lipoyl PF00364.17 OAI96615.1 - 6.9e-06 25.6 0.0 0.028 14.0 0.0 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD PF00529.15 OAI96615.1 - 0.036 13.3 32.5 0.4 9.9 0.0 2.8 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M23 PF01551.17 OAI96615.1 - 0.052 13.6 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M23 DUF4610 PF15384.1 OAI96615.1 - 0.072 12.6 0.7 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) Peptidase_S10 PF00450.17 OAI96620.1 - 6.1e-70 236.4 0.0 8.8e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAI96620.1 - 0.0032 17.3 0.0 0.0044 16.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0060 PF02694.10 OAI96621.1 - 0.0046 16.9 0.1 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family RVT_3 PF13456.1 OAI96621.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.17 OAI96622.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family GDA1_CD39 PF01150.12 OAI96625.1 - 1.3e-99 333.6 0.0 1.7e-99 333.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SR-25 PF10500.4 OAI96625.1 - 3.9 6.8 7.4 7.4 5.9 5.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cutinase PF01083.17 OAI96630.1 - 1.8e-16 60.3 0.8 2.4e-16 59.9 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAI96630.1 - 0.00011 21.7 0.2 0.00015 21.2 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 OAI96630.1 - 0.00048 19.8 0.3 0.00065 19.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI96630.1 - 0.0018 17.8 0.1 0.0026 17.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAI96630.1 - 0.0089 15.9 0.1 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 OAI96630.1 - 0.017 14.6 0.2 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase FSH1 PF03959.8 OAI96630.1 - 0.027 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 OAI96630.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Cutinase PF01083.17 OAI96631.1 - 6.5e-11 42.2 0.0 8.6e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 OAI96631.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_1 PF00078.22 OAI96644.1 - 3.9e-10 39.4 0.0 5.4e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ResIII PF04851.10 OAI96649.1 - 8e-06 25.7 0.0 8.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAI96649.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase N6_N4_Mtase PF01555.13 OAI96650.1 - 2.4e-12 46.8 0.0 3.1e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 DNA methylase Methyltransf_26 PF13659.1 OAI96650.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HTH_31 PF13560.1 OAI96651.1 - 4.1e-13 49.3 1.0 1e-12 48.0 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 OAI96651.1 - 1.4e-12 47.2 1.5 3.3e-12 46.0 1.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 OAI96651.1 - 2.5e-11 43.4 0.1 4.3e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 OAI96651.1 - 2.6e-05 23.9 0.9 4.4e-05 23.1 0.2 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_26 PF13443.1 OAI96651.1 - 0.00018 21.6 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain rve PF00665.21 OAI96653.1 - 1.9e-10 40.9 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain NUDIX_4 PF14815.1 OAI96692.1 - 6.9e-15 54.4 0.0 1.7e-14 53.1 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain EndIII_4Fe-2S PF10576.4 OAI96692.1 - 0.15 12.3 3.2 0.31 11.2 2.2 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III VID27 PF08553.5 OAI96699.1 - 1.1e-12 47.1 0.1 1.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF1966 PF09260.6 OAI96699.1 - 0.015 15.3 0.0 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Rrp15p PF07890.7 OAI96699.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Rrp15p Borrelia_P83 PF05262.6 OAI96702.1 - 0.12 10.6 5.2 0.12 10.6 3.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Seryl_tRNA_N PF02403.17 OAI96702.1 - 0.71 9.9 5.5 0.9 9.5 3.8 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_17 PF13431.1 OAI96713.1 - 5.5e-06 26.1 1.5 0.0087 16.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAI96713.1 - 2.2e-05 24.0 0.2 2.2e-05 24.0 0.1 3.8 3 1 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 OAI96713.1 - 0.00016 22.2 3.1 0.00016 22.2 2.1 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAI96713.1 - 0.0015 18.2 6.9 0.15 12.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 OAI96713.1 - 0.0027 17.7 1.5 0.017 15.2 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAI96713.1 - 0.0054 17.0 13.3 0.12 12.7 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAI96713.1 - 0.058 13.0 0.9 3.1 7.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAI96713.1 - 0.37 10.6 10.5 0.73 9.7 0.5 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAI96713.1 - 8.9 6.4 9.7 4.3 7.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAI96713.1 - 10 6.1 20.0 0.053 13.4 0.5 5.1 6 1 1 7 7 7 0 Tetratricopeptide repeat FHA PF00498.21 OAI96715.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sugarporin_N PF11471.3 OAI96715.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Pap_E4 PF02711.9 OAI96723.1 - 2.9 8.7 6.5 3.1 8.6 4.2 1.4 1 1 0 1 1 1 0 E4 protein FliJ PF02050.11 OAI96724.1 - 1.2 9.2 8.6 0.74 9.8 2.8 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein E2R135 PF11570.3 OAI96728.1 - 0.052 13.6 5.4 0.11 12.5 3.7 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Erp_C PF06780.6 OAI96728.1 - 0.053 13.3 4.3 0.086 12.6 2.6 1.6 1 1 0 1 1 1 0 Erp protein C-terminus Spc7 PF08317.6 OAI96728.1 - 0.069 11.8 4.3 0.1 11.2 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 OAI96728.1 - 0.17 10.8 5.1 0.37 9.6 3.6 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 OAI96728.1 - 0.45 9.5 2.4 0.64 9.0 1.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.3 OAI96728.1 - 0.64 9.8 9.3 0.13 12.0 4.1 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 OAI96728.1 - 2.2 8.0 11.3 4.7 6.9 4.8 2.6 2 1 1 3 3 3 0 Laminin Domain II RVT_1 PF00078.22 OAI96731.1 - 1.3e-31 109.6 0.0 1.9e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FHA PF00498.21 OAI96741.1 - 0.00057 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain RVT_1 PF00078.22 OAI96758.1 - 3.8e-24 85.2 0.0 6.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI96758.1 - 3.1e-10 39.7 0.0 5.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAI96758.1 - 0.00018 21.5 0.2 0.00038 20.4 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pribosyltran PF00156.22 OAI96760.1 - 0.067 12.9 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Ribosomal_60s PF00428.14 OAI96760.1 - 3.8 7.9 7.7 1.1 9.7 2.6 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein GATA PF00320.22 OAI96761.1 - 0.027 13.8 3.5 0.053 12.8 2.4 1.5 1 0 0 1 1 1 0 GATA zinc finger Zn_Tnp_IS1595 PF12760.2 OAI96761.1 - 0.23 11.3 1.5 0.37 10.6 1.1 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain FimP PF09766.4 OAI96761.1 - 0.26 10.3 1.5 0.32 10.0 1.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Cmc1 PF08583.5 OAI96764.1 - 9.9e-14 50.8 1.2 1.2e-13 50.5 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NIP_1 PF08995.5 OAI96764.1 - 0.068 13.3 0.3 0.086 13.0 0.2 1.1 1 0 0 1 1 1 0 Necrosis inducing protein-1 NDUF_B7 PF05676.8 OAI96764.1 - 0.11 11.9 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) OPT PF03169.10 OAI96771.1 - 1.6e-62 211.8 18.4 1.9e-62 211.6 12.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Helicase_C PF00271.26 OAI96773.1 - 1.4e-06 28.0 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.22 OAI96785.1 - 1.1e-11 44.4 0.0 2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) eIF3_subunit PF08597.5 OAI96789.1 - 0.075 12.5 0.9 0.11 12.0 0.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PRCC PF10253.4 OAI96789.1 - 0.69 10.5 12.0 1.8 9.2 8.3 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.8 OAI96789.1 - 4.1 7.2 10.0 5.1 6.8 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.24 OAI96794.1 - 2.8e-14 52.9 0.0 3.4e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI96794.1 - 1.3e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAI96794.1 - 0.042 12.6 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C PF00271.26 OAI96798.1 - 5.7e-09 35.7 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pterin_bind PF00809.17 OAI96800.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Pterin binding enzyme GDC-P PF02347.11 OAI96803.1 - 1.6e-15 56.7 0.0 2.1e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein DUF45 PF01863.12 OAI96808.1 - 1.5e-58 198.0 2.2 2e-58 197.5 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF45 ResIII PF04851.10 OAI96808.1 - 9.9e-19 67.8 0.1 2.9e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit WLM PF08325.5 OAI96808.1 - 1.1e-06 28.6 0.5 3.3e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 WLM domain SprT-like PF10263.4 OAI96808.1 - 9.6e-05 22.0 0.4 0.00025 20.7 0.2 1.6 1 0 0 1 1 1 1 SprT-like family SNF2_N PF00176.18 OAI96808.1 - 0.0059 15.4 0.2 0.029 13.1 0.0 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain RimK PF08443.6 OAI96808.1 - 0.028 13.8 0.0 0.078 12.4 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF87 PF01935.12 OAI96808.1 - 0.054 13.3 1.5 0.83 9.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF148 PF02520.12 OAI96808.1 - 0.87 9.3 5.3 1.9 8.2 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function DUF148 Nop14 PF04147.7 OAI96820.1 - 2.8 5.7 6.4 3.1 5.5 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 OAI96824.1 - 4.6e-28 98.0 0.0 8.7e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI96824.1 - 1.2e-13 51.5 0.0 2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI96824.1 - 0.00079 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Pkinase PF00069.20 OAI96826.1 - 0.00051 19.2 0.0 0.0019 17.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96826.1 - 0.00082 18.5 0.0 0.13 11.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase NTP_transf_2 PF01909.18 OAI96836.1 - 0.037 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain DEAD PF00270.24 OAI96845.1 - 0.00036 20.0 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF87 PF01935.12 OAI96845.1 - 0.084 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 zf-C2H2 PF00096.21 OAI96845.1 - 0.83 10.1 11.6 1.9 8.9 2.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Chromo PF00385.19 OAI96851.1 - 5e-05 22.8 1.3 0.00011 21.8 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chorion_2 PF03964.10 OAI96854.1 - 0.9 10.1 8.5 0.1 13.1 1.8 2.2 2 0 0 2 2 2 0 Chorion family 2 Pox_A_type_inc PF04508.7 OAI96854.1 - 2.5 8.1 6.1 0.8 9.6 0.5 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Rad60-SLD PF11976.3 OAI96861.1 - 2.3e-08 33.6 0.9 0.75 9.5 0.2 4.5 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like Clusterin PF01093.12 OAI96861.1 - 0.0093 14.8 0.3 0.016 14.0 0.2 1.2 1 0 0 1 1 1 1 Clusterin zf-CCHC PF00098.18 OAI96861.1 - 0.64 10.0 6.0 1.2 9.2 4.2 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAI96861.1 - 1 8.9 5.3 3.4 7.2 3.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Cmc1 PF08583.5 OAI96863.1 - 5.8e-10 38.7 0.1 6.3e-10 38.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NIP_1 PF08995.5 OAI96863.1 - 0.036 14.2 0.5 0.038 14.1 0.3 1.1 1 0 0 1 1 1 0 Necrosis inducing protein-1 CHCH PF06747.8 OAI96863.1 - 0.13 12.1 0.3 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 CHCH domain Vmethyltransf PF01660.12 OAI96873.1 - 2.6e-32 111.8 0.0 2.1e-31 108.8 0.0 2.0 2 0 0 2 2 2 1 Viral methyltransferase AAA_25 PF13481.1 OAI96873.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 OAI96873.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 OAI96873.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ETX_MTX2 PF03318.8 OAI96873.1 - 0.37 10.2 0.0 0.58 9.6 0.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Het-C PF07217.6 OAI96878.1 - 3.1e-74 250.2 0.2 2.9e-57 194.2 0.0 2.0 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.3 OAI96878.1 - 0.0021 18.1 0.4 0.0033 17.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Abhydrolase_5 PF12695.2 OAI96884.1 - 3.1e-05 23.7 0.0 0.00031 20.5 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI96884.1 - 0.00048 19.7 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 OAI96884.1 - 0.0021 17.5 0.1 0.0048 16.3 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 OAI96884.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family SpoVA PF03862.8 OAI96887.1 - 0.098 12.7 0.2 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 SpoVA protein Spo0M PF07070.6 OAI96887.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.0 1 0 0 1 1 1 0 SpoOM protein HRM PF02793.17 OAI96890.1 - 0.014 15.4 3.5 0.027 14.4 2.4 1.6 1 0 0 1 1 1 0 Hormone receptor domain TFIIE_alpha PF02002.12 OAI96891.1 - 2.8e-10 39.6 0.0 6.5e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit zf-C2H2_6 PF13912.1 OAI96891.1 - 0.16 11.8 0.1 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DBD_Tnp_Mut PF03108.10 OAI96900.1 - 8.6e-09 34.8 0.2 1.4e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 MuDR family transposase RVT_3 PF13456.1 OAI96905.1 - 0.019 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RVP_2 PF08284.6 OAI96906.1 - 0.0034 17.3 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI96906.1 - 0.017 14.9 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAI96906.1 - 0.038 14.0 0.5 0.13 12.3 0.1 2.2 1 1 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.18 OAI96906.1 - 0.15 12.0 1.1 0.31 11.0 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAI96910.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DAGK_prokar PF01219.14 OAI96912.1 - 0.024 14.2 2.5 0.04 13.5 1.8 1.3 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase E1-E2_ATPase PF00122.15 OAI96921.1 - 0.012 14.6 0.1 0.034 13.1 0.0 1.7 1 1 0 1 1 1 0 E1-E2 ATPase Peptidase_C39_2 PF13529.1 OAI96931.1 - 0.072 13.4 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Gly_transf_sug PF04488.10 OAI96934.1 - 2.6e-20 72.7 0.1 4.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 OAI96934.1 - 0.00063 18.3 0.9 0.069 11.6 0.2 2.9 3 0 0 3 3 3 3 TcdA/TcdB catalytic glycosyltransferase domain Uds1 PF15456.1 OAI96940.1 - 8.3e-05 22.5 2.0 0.0001 22.2 1.4 1.0 1 0 0 1 1 1 1 Up-regulated During Septation Tropomyosin_1 PF12718.2 OAI96940.1 - 0.0011 18.8 3.8 0.0014 18.5 2.7 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF2353 PF09789.4 OAI96940.1 - 0.0013 18.0 1.7 0.0016 17.7 1.2 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TMF_DNA_bd PF12329.3 OAI96940.1 - 0.0026 17.5 6.7 0.018 14.8 3.7 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 OAI96940.1 - 0.0035 16.9 0.3 0.0041 16.7 0.2 1.1 1 0 0 1 1 1 1 IncA protein TMF_TATA_bd PF12325.3 OAI96940.1 - 0.0082 15.8 2.8 0.014 15.1 1.9 1.3 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Cob_adeno_trans PF01923.13 OAI96940.1 - 0.011 15.4 0.4 0.016 14.9 0.3 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Sirohm_synth_C PF14823.1 OAI96940.1 - 0.011 14.9 0.5 0.019 14.2 0.1 1.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF904 PF06005.7 OAI96940.1 - 0.012 15.8 5.4 0.41 10.9 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) GAS PF13851.1 OAI96940.1 - 0.013 14.7 3.1 0.015 14.4 2.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding WD40_alt PF14077.1 OAI96940.1 - 0.014 15.0 2.3 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif ADIP PF11559.3 OAI96940.1 - 0.019 14.8 3.9 0.21 11.5 2.5 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 OAI96940.1 - 0.023 14.1 0.2 0.091 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.16 OAI96940.1 - 0.024 14.5 3.8 1.1 9.3 0.2 2.5 2 1 0 2 2 2 0 bZIP transcription factor Med9 PF07544.8 OAI96940.1 - 0.026 14.2 0.7 0.041 13.6 0.5 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TelA PF05816.6 OAI96940.1 - 0.026 13.2 0.6 0.04 12.6 0.4 1.3 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) ATG16 PF08614.6 OAI96940.1 - 0.03 14.1 3.5 0.18 11.6 2.4 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Filament PF00038.16 OAI96940.1 - 0.036 13.5 2.1 2.7 7.3 0.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein DivIC PF04977.10 OAI96940.1 - 0.04 13.4 1.2 1.4 8.4 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator Reo_sigmaC PF04582.7 OAI96940.1 - 0.04 13.0 0.9 0.069 12.3 0.3 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DivIVA PF05103.8 OAI96940.1 - 0.041 13.9 1.6 0.057 13.4 1.1 1.1 1 0 0 1 1 1 0 DivIVA protein TSC22 PF01166.13 OAI96940.1 - 0.043 13.7 0.3 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family BRE1 PF08647.6 OAI96940.1 - 0.044 13.7 3.3 0.079 12.9 0.4 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.4 OAI96940.1 - 0.06 13.4 0.6 0.12 12.4 0.4 1.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.7 OAI96940.1 - 0.066 13.0 1.2 0.31 10.8 0.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMPK_coil PF08826.5 OAI96940.1 - 0.068 13.0 2.9 0.085 12.7 0.2 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like Spc7 PF08317.6 OAI96940.1 - 0.073 11.7 0.4 0.096 11.3 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lebercilin PF15619.1 OAI96940.1 - 0.076 12.4 3.7 0.11 11.8 2.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease BBS2_C PF14782.1 OAI96940.1 - 0.097 11.2 0.7 0.095 11.2 0.5 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Cortex-I_coil PF09304.5 OAI96940.1 - 0.11 12.5 5.9 1.6 8.8 1.2 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil Flagellin_C PF00700.16 OAI96940.1 - 0.12 12.5 1.8 0.23 11.6 0.4 1.9 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region CENP-F_leu_zip PF10473.4 OAI96940.1 - 0.13 12.0 3.5 0.3 10.9 2.4 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 OAI96940.1 - 0.15 12.0 3.5 7.6 6.5 2.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 OAI96940.1 - 0.17 12.2 1.7 1.2 9.5 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 OAI96940.1 - 0.21 9.9 2.5 0.39 9.1 1.7 1.4 1 1 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 OAI96940.1 - 0.23 11.7 1.0 4.5 7.5 0.7 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Phage_lysis PF03245.8 OAI96940.1 - 0.23 11.4 2.8 0.43 10.5 1.9 1.5 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein DUF4315 PF14193.1 OAI96940.1 - 0.31 11.0 2.1 17 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Cep57_CLD_2 PF14197.1 OAI96940.1 - 0.59 10.1 5.7 2.2 8.3 1.2 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Mto2_bdg PF12808.2 OAI96940.1 - 6.6 6.9 8.3 2.1 8.5 1.1 2.3 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Atg31 PF09795.4 OAI96942.1 - 0.087 12.5 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 Autophagy-related protein 31 TPK_catalytic PF04263.11 OAI96943.1 - 1.5e-19 69.7 0.0 2.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 OAI96943.1 - 1.6e-09 37.3 0.0 2.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Cut8_N PF14482.1 OAI96959.1 - 0.0024 17.8 0.1 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Myc_N PF01056.13 OAI96959.1 - 0.0049 16.0 6.0 0.0054 15.9 4.2 1.0 1 0 0 1 1 1 1 Myc amino-terminal region CENP-B_dimeris PF09026.5 OAI96959.1 - 0.0057 16.8 6.9 0.0078 16.4 4.7 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DUF3402 PF11882.3 OAI96959.1 - 0.0069 15.4 1.6 0.007 15.4 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) CDC27 PF09507.5 OAI96959.1 - 0.0095 15.2 6.4 0.011 15.0 4.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF2890 PF11081.3 OAI96959.1 - 0.011 15.8 5.6 0.012 15.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) FAM176 PF14851.1 OAI96959.1 - 0.014 15.1 4.0 0.015 14.9 2.7 1.1 1 0 0 1 1 1 0 FAM176 family Mannosyl_trans3 PF11051.3 OAI96959.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.0 1 0 0 1 1 1 0 Mannosyltransferase putative Vfa1 PF08432.5 OAI96959.1 - 0.019 15.0 4.0 0.02 14.9 2.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Sigma70_ner PF04546.8 OAI96959.1 - 0.02 14.5 7.4 0.023 14.3 5.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BSP_II PF05432.6 OAI96959.1 - 0.027 13.7 16.0 0.035 13.4 11.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YqfQ PF14181.1 OAI96959.1 - 0.033 14.2 5.2 0.036 14.1 3.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Retinal PF15449.1 OAI96959.1 - 0.033 11.8 2.8 0.035 11.7 1.9 1.0 1 0 0 1 1 1 0 Retinal protein GOLD_2 PF13897.1 OAI96959.1 - 0.034 14.3 6.0 0.045 13.9 4.1 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking SDA1 PF05285.7 OAI96959.1 - 0.038 13.2 8.9 0.041 13.1 6.2 1.1 1 0 0 1 1 1 0 SDA1 TcdB_toxin_midN PF12256.3 OAI96959.1 - 0.038 13.4 0.5 0.049 13.0 0.3 1.1 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Suf PF05843.9 OAI96959.1 - 0.041 13.6 2.0 0.048 13.3 1.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Daxx PF03344.10 OAI96959.1 - 0.041 12.3 12.1 0.045 12.2 8.4 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 OAI96959.1 - 0.053 13.4 7.9 0.066 13.0 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 OAI96959.1 - 0.058 11.4 7.6 0.061 11.3 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF506 PF04720.7 OAI96959.1 - 0.074 12.6 1.6 0.082 12.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Sporozoite_P67 PF05642.6 OAI96959.1 - 0.089 10.6 3.0 0.097 10.5 2.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TEX19 PF15553.1 OAI96959.1 - 0.12 12.2 6.2 0.16 11.8 4.3 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 XAP5 PF04921.9 OAI96959.1 - 0.13 11.8 5.6 0.14 11.6 3.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator RRN3 PF05327.6 OAI96959.1 - 0.14 10.1 4.1 0.16 10.0 2.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Med17 PF10156.4 OAI96959.1 - 0.17 10.1 6.0 0.19 9.9 4.1 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Zip PF02535.17 OAI96959.1 - 0.17 10.8 1.2 0.21 10.5 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RNase_H2-Ydr279 PF09468.5 OAI96959.1 - 0.19 10.8 5.2 0.23 10.6 3.6 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RXT2_N PF08595.6 OAI96959.1 - 0.22 11.2 6.4 0.31 10.8 4.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_Rpc4 PF05132.9 OAI96959.1 - 0.24 11.3 6.5 0.33 10.9 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 NOA36 PF06524.7 OAI96959.1 - 0.27 10.4 7.7 0.32 10.1 5.4 1.1 1 0 0 1 1 1 0 NOA36 protein Tom37_C PF11801.3 OAI96959.1 - 0.28 11.0 3.0 0.3 10.9 2.1 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF912 PF06024.7 OAI96959.1 - 0.28 11.2 2.6 0.39 10.8 1.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cnd2 PF05786.9 OAI96959.1 - 0.29 9.6 9.5 0.33 9.4 6.6 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 PBP1_TM PF14812.1 OAI96959.1 - 0.36 11.1 12.8 0.54 10.6 8.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 OAI96959.1 - 0.36 8.6 14.1 0.43 8.4 9.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.1 OAI96959.1 - 0.42 8.2 14.2 0.43 8.2 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CobT PF06213.7 OAI96959.1 - 0.46 9.5 13.7 0.53 9.3 9.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HSP90 PF00183.13 OAI96959.1 - 0.51 8.6 10.1 0.6 8.4 7.0 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF2201_N PF13203.1 OAI96959.1 - 0.53 9.3 8.4 0.7 9.0 5.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Nucleoplasmin PF03066.10 OAI96959.1 - 0.58 9.6 19.1 0.75 9.2 13.3 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF3381 PF11861.3 OAI96959.1 - 0.77 9.2 13.9 0.95 8.9 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3464 PF11947.3 OAI96959.1 - 0.81 9.1 3.2 1.1 8.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4192 PF13830.1 OAI96959.1 - 0.85 9.2 4.1 0.98 8.9 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) DUF4637 PF15470.1 OAI96959.1 - 0.86 9.2 7.1 0.98 9.0 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Adeno_terminal PF02459.10 OAI96959.1 - 1.1 7.3 8.8 1.3 7.0 6.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Prog_receptor PF02161.10 OAI96959.1 - 1.2 7.9 5.3 1.2 7.8 3.7 1.0 1 0 0 1 1 1 0 Progesterone receptor Pox_Ag35 PF03286.9 OAI96959.1 - 1.2 8.6 10.7 1.5 8.2 7.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pox_RNA_Pol_19 PF05320.7 OAI96959.1 - 1.4 8.6 11.1 1.9 8.2 7.7 1.3 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DDHD PF02862.12 OAI96959.1 - 1.4 8.6 4.3 1.7 8.4 3.0 1.1 1 0 0 1 1 1 0 DDHD domain TRAP_alpha PF03896.11 OAI96959.1 - 1.8 7.4 9.5 2.2 7.2 6.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 OAI96959.1 - 2.2 6.9 15.8 2.8 6.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hid1 PF12722.2 OAI96959.1 - 3.2 5.3 5.3 3.8 5.0 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 OAI96959.1 - 3.5 6.9 14.2 4.4 6.6 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 OAI96959.1 - 3.7 5.8 15.8 4.4 5.5 11.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Paf1 PF03985.8 OAI96959.1 - 4.6 5.8 19.2 5.5 5.6 13.3 1.1 1 0 0 1 1 1 0 Paf1 DUF3306 PF11748.3 OAI96959.1 - 4.6 7.9 11.7 5.9 7.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) VID27 PF08553.5 OAI96959.1 - 4.9 5.2 12.3 5.5 5.0 8.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein NARP1 PF12569.3 OAI96959.1 - 5.7 5.5 9.2 6.8 5.3 6.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FimP PF09766.4 OAI96959.1 - 7.7 5.4 13.1 9.2 5.2 9.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Nucleo_P87 PF07267.6 OAI96959.1 - 7.7 5.0 8.5 9.1 4.8 5.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spore_coat_CotO PF14153.1 OAI96959.1 - 9.2 5.6 14.9 12 5.3 10.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO ERF PF04404.7 OAI96959.1 - 9.3 5.7 14.1 13 5.2 9.8 1.2 1 0 0 1 1 1 0 ERF superfamily RVT_1 PF00078.22 OAI96962.1 - 0.00044 19.6 0.0 0.011 15.0 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BESS PF02944.15 OAI96962.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 BESS motif DUF935 PF06074.7 OAI96967.1 - 0.0018 17.0 5.4 0.0021 16.8 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF935) EzrA PF06160.7 OAI96967.1 - 0.0039 15.4 7.4 0.0047 15.1 5.1 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA WEMBL PF05701.6 OAI96967.1 - 0.0041 15.6 12.4 0.0049 15.3 8.6 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF342 PF03961.8 OAI96967.1 - 0.0049 15.3 2.3 0.0057 15.1 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Sec2p PF06428.6 OAI96967.1 - 0.0062 16.3 12.0 0.22 11.4 2.6 2.2 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p IncA PF04156.9 OAI96967.1 - 0.015 14.8 9.7 0.021 14.4 6.7 1.2 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 OAI96967.1 - 0.018 14.4 9.6 0.17 11.2 1.9 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 YqhG PF11079.3 OAI96967.1 - 0.038 12.8 0.5 0.044 12.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function AATF-Che1 PF13339.1 OAI96967.1 - 0.056 13.5 4.4 0.067 13.3 3.0 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Mnd1 PF03962.10 OAI96967.1 - 0.062 12.9 9.9 0.099 12.3 6.9 1.3 1 0 0 1 1 1 0 Mnd1 family YlqD PF11068.3 OAI96967.1 - 0.078 13.0 12.6 0.11 12.5 8.5 1.3 1 1 0 1 1 1 0 YlqD protein LXG PF04740.7 OAI96967.1 - 0.089 12.5 3.3 0.11 12.2 2.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily HpaB_N PF11794.3 OAI96967.1 - 0.099 12.0 1.1 0.12 11.7 0.8 1.1 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal APG6 PF04111.7 OAI96967.1 - 0.1 11.6 11.0 0.13 11.2 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec8_exocyst PF04048.9 OAI96967.1 - 0.12 11.9 3.5 0.18 11.4 0.4 2.0 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain ERM PF00769.14 OAI96967.1 - 0.12 11.8 16.3 0.18 11.3 11.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IF-2B PF01008.12 OAI96967.1 - 0.12 11.2 3.6 0.15 11.0 2.5 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF3584 PF12128.3 OAI96967.1 - 0.2 8.9 12.9 0.25 8.6 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4094 PF13334.1 OAI96967.1 - 0.21 11.9 2.4 0.45 10.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) AAA_32 PF13654.1 OAI96967.1 - 0.45 9.1 9.8 0.57 8.7 6.8 1.0 1 0 0 1 1 1 0 AAA domain DUF3682 PF12446.3 OAI96967.1 - 0.48 10.7 5.8 0.7 10.1 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF745 PF05335.8 OAI96967.1 - 0.51 9.8 10.3 0.31 10.5 5.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Tho2 PF11262.3 OAI96967.1 - 0.56 9.2 3.1 0.68 8.9 2.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TPR_MLP1_2 PF07926.7 OAI96967.1 - 1 9.1 15.6 0.9 9.2 10.0 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 OAI96967.1 - 1.1 9.3 5.5 1.5 8.9 3.8 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 OAI96967.1 - 1.3 6.7 4.6 1.6 6.5 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.7 OAI96967.1 - 1.8 8.3 8.4 6.4 6.5 0.7 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3763 PF12592.3 OAI96967.1 - 2 8.1 8.8 2.9 7.6 0.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3763) RGS-like PF09128.6 OAI96967.1 - 2.9 7.3 8.6 7.3 6.0 1.6 2.1 1 1 1 2 2 2 0 Regulator of G protein signalling-like domain Rotamase PF00639.16 OAI96967.1 - 3 8.6 7.4 26 5.6 2.1 2.3 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF3391 PF11871.3 OAI96967.1 - 3.5 7.8 7.3 21 5.3 4.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Seryl_tRNA_N PF02403.17 OAI96967.1 - 4.2 7.4 9.4 8.7 6.4 0.9 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 OAI96967.1 - 4.3 6.9 11.1 3.7 7.2 1.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit Sin3_corepress PF08295.7 OAI96967.1 - 6 6.6 8.4 11 5.7 1.0 2.1 1 1 1 2 2 2 0 Sin3 family co-repressor DUF3450 PF11932.3 OAI96967.1 - 6.3 5.9 13.6 1.6e+02 1.3 9.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3307 PF11750.3 OAI96970.1 - 0.1 12.3 3.3 0.13 11.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) Brr6_like_C_C PF10104.4 OAI96975.1 - 6.9e-07 28.8 0.5 1e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF842 PF05811.8 OAI96975.1 - 0.24 10.8 4.9 0.97 8.8 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AAA PF00004.24 OAI96978.1 - 4.4e-33 114.3 0.0 6.5e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAI96978.1 - 4.4e-07 30.1 0.3 0.0024 18.0 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 OAI96978.1 - 1.8e-05 24.7 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 OAI96978.1 - 4.9e-05 22.8 0.4 0.038 13.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 OAI96978.1 - 5.5e-05 23.2 0.1 0.00046 20.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain KaiC PF06745.8 OAI96978.1 - 0.00033 19.8 0.1 0.033 13.3 0.1 2.2 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.1 OAI96978.1 - 0.00039 20.3 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAI96978.1 - 0.00098 18.8 0.3 0.0061 16.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 OAI96978.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 OAI96978.1 - 0.0015 18.2 0.1 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 OAI96978.1 - 0.0018 17.4 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAI96978.1 - 0.0028 18.4 0.0 0.0048 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAI96978.1 - 0.0038 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 OAI96978.1 - 0.0061 15.5 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 OAI96978.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAI96978.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 OAI96978.1 - 0.016 13.9 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 OAI96978.1 - 0.027 14.6 0.0 0.087 13.0 0.0 2.0 2 1 0 2 2 2 0 RNA helicase CPT PF07931.7 OAI96978.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.7 OAI96978.1 - 0.032 13.8 0.1 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 OAI96978.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAI96978.1 - 0.046 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 OAI96978.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 OAI96978.1 - 0.098 11.8 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 OAI96978.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 OAI96978.1 - 0.1 12.4 0.0 4.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase rve PF00665.21 OAI96980.1 - 3.5e-16 59.4 0.0 7.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI96980.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 OAI96992.1 - 5.6e-46 156.7 0.0 9.5e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI96992.1 - 8.4e-30 103.6 0.0 3.1e-29 101.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 OAI96992.1 - 0.0032 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 OAI96992.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 OAI96992.1 - 0.46 9.2 0.0 0.82 8.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4124 PF13511.1 OAI96994.1 - 2.4e-13 49.8 0.0 3.5e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) Glutaredoxin PF00462.19 OAI96994.1 - 4.3e-12 45.8 0.0 6.1e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 OAI96994.1 - 0.0014 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 OAI96994.1 - 0.0018 18.4 0.3 0.069 13.3 0.2 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.15 OAI96994.1 - 0.0029 17.2 0.1 0.0058 16.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 OAI96994.1 - 0.014 15.3 0.1 0.13 12.3 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like ArsC PF03960.10 OAI96994.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 ArsC family DUF836 PF05768.9 OAI96994.1 - 0.043 14.0 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) AhpC-TSA PF00578.16 OAI96994.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family DUF2826 PF11442.3 OAI96994.1 - 0.14 11.8 0.0 1.6 8.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2826) DUF1776 PF08643.5 OAI96997.1 - 0.00088 18.4 0.0 0.073 12.1 0.0 2.4 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) MIP-T3 PF10243.4 OAI96997.1 - 0.59 8.5 5.5 0.15 10.5 0.1 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Dimer_Tnp_hAT PF05699.9 OAI97000.1 - 1e-15 57.1 0.0 2.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ORC4_C PF14629.1 OAI97000.1 - 0.085 12.2 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus rve PF00665.21 OAI97004.1 - 4.4e-22 78.4 0.0 1.4e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAI97004.1 - 2.1e-05 24.0 0.1 4.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_2 PF13696.1 OAI97004.1 - 0.0087 15.5 2.0 0.02 14.3 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAI97004.1 - 0.0094 15.8 4.4 0.019 14.8 3.1 1.6 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.1 OAI97004.1 - 0.012 15.0 0.0 0.043 13.3 0.0 2.0 1 1 0 1 1 1 0 Integrase core domain DnaJ_CXXCXGXG PF00684.14 OAI97004.1 - 0.067 13.2 5.1 0.17 11.9 3.5 1.6 1 0 0 1 1 1 0 DnaJ central domain Dynamitin PF04912.9 OAI97004.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Dynamitin zf-CCHC_3 PF13917.1 OAI97004.1 - 0.13 12.0 2.4 0.3 10.8 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle RNA_GG_bind PF10258.4 OAI97004.1 - 0.21 11.3 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 PHAX RNA-binding domain Gemini_C4 PF01492.12 OAI97010.1 - 0.087 12.5 0.3 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Geminivirus C4 protein DEAD PF00270.24 OAI97015.1 - 1.4e-09 37.7 0.0 2.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI97015.1 - 3.1e-06 26.9 0.0 6.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.22 OAI97023.1 - 1.5e-17 63.6 0.0 2.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97023.1 - 1.4e-15 57.4 0.0 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97023.1 - 0.0013 19.1 0.2 0.0088 16.5 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI97023.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Helicase_C PF00271.26 OAI97026.1 - 9.9e-13 47.7 0.0 2.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI97026.1 - 5.7e-06 25.9 0.0 4.3e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF1931 PF09123.6 OAI97026.1 - 0.19 11.6 0.0 0.47 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) SIR2 PF02146.12 OAI97030.1 - 0.0088 15.7 0.1 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 Sir2 family zf-BED PF02892.10 OAI97033.1 - 3.2e-07 29.9 5.1 5.5e-07 29.2 3.5 1.4 1 0 0 1 1 1 1 BED zinc finger BIR PF00653.16 OAI97033.1 - 0.029 14.7 0.3 0.053 13.9 0.2 1.4 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain ubiquitin PF00240.18 OAI97035.1 - 7e-136 441.8 24.5 1.1e-33 114.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 OAI97035.1 - 1.2e-77 255.5 22.7 5.6e-19 67.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAI97035.1 - 5.2e-24 84.3 11.9 0.00016 21.8 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAI97035.1 - 4.3e-21 75.2 1.4 0.0019 17.9 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 OAI97035.1 - 6.6e-14 51.8 2.8 0.11 12.6 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAI97035.1 - 8.9e-14 51.3 3.5 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 OAI97035.1 - 1.4e-10 41.0 0.0 1.5 8.9 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 OAI97035.1 - 2.2e-06 27.0 0.7 1.3 8.0 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 OAI97035.1 - 4.5e-06 26.3 5.5 6.8 6.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain IGR PF09597.5 OAI97035.1 - 1.4e-05 24.9 0.3 24 4.9 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif Big_3_3 PF13750.1 OAI97035.1 - 2.4e-05 23.8 0.1 19 4.6 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 OAI97035.1 - 2.9e-05 23.8 6.9 7.8 6.5 0.1 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 OAI97035.1 - 0.0024 18.1 0.7 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain USP7_C2 PF14533.1 OAI97035.1 - 0.0035 16.8 5.2 23 4.3 0.0 3.8 1 1 1 4 4 4 0 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 OAI97035.1 - 0.0052 15.1 14.4 3.6 5.8 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 OAI97035.1 - 0.0095 16.0 5.7 56 3.9 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Sortase PF04203.8 OAI97035.1 - 0.02 14.4 2.5 37 3.9 0.0 3.9 2 1 1 4 4 4 0 Sortase family Tash_PEST PF07708.6 OAI97035.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif CTDII PF01556.13 OAI97035.1 - 0.049 13.5 17.0 6.4 6.7 0.3 4.5 1 1 3 4 4 4 0 DnaJ C terminal domain GABP-alpha PF11620.3 OAI97035.1 - 0.076 13.0 8.3 47 4.0 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 OAI97035.1 - 0.95 9.4 7.8 1.2e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 OAI97035.1 - 1.1 9.3 14.8 57 3.8 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain zf-C3HC4_3 PF13920.1 OAI97038.1 - 0.81 9.4 7.2 1.5 8.5 5.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) JmjC PF02373.17 OAI97045.1 - 3.7e-13 49.7 0.0 1e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF3135 PF11333.3 OAI97045.1 - 0.0012 18.9 0.4 0.003 17.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) Cupin_4 PF08007.7 OAI97045.1 - 0.0031 16.8 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein FYVE PF01363.16 OAI97045.1 - 0.013 15.4 2.9 0.013 15.4 2.0 1.9 2 0 0 2 2 2 0 FYVE zinc finger Cupin_2 PF07883.6 OAI97045.1 - 0.065 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Fer2 PF00111.22 OAI97048.1 - 2.3e-10 40.0 0.4 2.8e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ATP-grasp_4 PF13535.1 OAI97049.1 - 3.3e-35 121.4 0.1 4.8e-29 101.4 0.0 2.5 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAI97049.1 - 1.2e-12 47.2 0.0 9.8e-09 34.3 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 OAI97049.1 - 3.4e-06 27.0 0.0 7.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAI97049.1 - 0.066 12.5 0.0 0.9 8.8 0.0 2.3 2 1 0 2 2 2 0 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 OAI97049.1 - 0.16 11.2 0.0 4.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF1768 PF08719.6 OAI97053.1 - 1.7e-24 86.3 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.17 OAI97056.1 - 1.1e-08 34.6 0.1 3.7e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI97056.1 - 2.8e-07 30.4 0.0 5.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI97056.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF948 PF06103.6 OAI97056.1 - 0.036 13.9 4.7 0.42 10.4 0.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NIT PF08376.5 OAI97056.1 - 0.11 12.0 5.4 0.21 11.0 0.2 2.4 2 0 0 2 2 2 0 Nitrate and nitrite sensing DUF445 PF04286.7 OAI97056.1 - 0.21 11.0 4.2 0.2 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Apo-CIII PF05778.7 OAI97056.1 - 0.68 9.3 12.4 0.79 9.1 0.7 4.2 3 2 1 5 5 5 0 Apolipoprotein CIII (Apo-CIII) YtxH PF12732.2 OAI97056.1 - 3.1 8.2 24.2 23 5.4 0.1 4.0 2 1 0 2 2 2 0 YtxH-like protein DUF883 PF05957.8 OAI97056.1 - 4.6 7.7 15.7 1.2 9.5 5.6 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 OAI97056.1 - 8.5 6.4 18.6 0.58 10.2 5.7 3.0 3 1 0 3 3 3 0 DivIVA protein DUF3505 PF12013.3 OAI97058.1 - 4.5e-10 39.7 2.2 4.5e-10 39.7 1.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 OAI97058.1 - 0.051 13.8 4.4 0.085 13.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Cmc1 PF08583.5 OAI97066.1 - 3e-13 49.3 1.8 3.8e-13 49.0 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NIP_1 PF08995.5 OAI97066.1 - 0.067 13.3 0.3 0.086 13.0 0.2 1.1 1 0 0 1 1 1 0 Necrosis inducing protein-1 NDUF_B7 PF05676.8 OAI97066.1 - 0.11 11.9 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RGCC PF15151.1 OAI97067.1 - 0.21 12.0 1.7 0.36 11.2 1.2 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family Het-C PF07217.6 OAI97076.1 - 9e-51 172.7 0.0 1e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1572 PF07609.6 OAI97076.1 - 0.018 14.5 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) Sigma70_r1_2 PF00140.15 OAI97077.1 - 0.046 13.3 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Ribonuclease_3 PF00636.21 OAI97083.1 - 9e-25 87.3 0.0 7.1e-11 42.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAI97083.1 - 1.7e-11 44.1 0.1 0.00016 21.6 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like DUF4413 PF14372.1 OAI97087.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) MULE PF10551.4 OAI97090.1 - 5.6e-10 39.2 0.0 1.2e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain VEGF_C PF14554.1 OAI97090.1 - 0.011 15.4 1.2 0.026 14.3 0.8 1.5 1 0 0 1 1 1 0 VEGF heparin-binding domain Transposase_mut PF00872.13 OAI97090.1 - 0.024 13.1 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family FHA PF00498.21 OAI97105.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 FHA domain Abhydrolase_3 PF07859.8 OAI97114.1 - 0.003 17.1 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAI97114.1 - 0.0072 15.5 0.0 0.0074 15.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAI97114.1 - 0.027 14.2 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DNA_pol_viral_C PF00336.13 OAI97120.1 - 0.00079 18.7 0.1 0.026 13.7 0.0 2.5 2 1 0 2 2 2 2 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.17 OAI97121.1 - 2.2e-05 24.2 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF1491 PF07372.7 OAI97123.1 - 0.054 13.4 4.7 0.82 9.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1491) adh_short_C2 PF13561.1 OAI97130.1 - 3.9e-32 111.9 0.0 5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAI97130.1 - 6.3e-28 97.7 0.2 7.9e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI97130.1 - 3.4e-10 39.8 0.1 5e-10 39.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAI97130.1 - 0.00013 21.5 0.1 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAI97130.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TPR_7 PF13176.1 OAI97135.1 - 0.29 11.0 2.9 2.3 8.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Transposase_21 PF02992.9 OAI97139.1 - 4.4e-25 88.0 0.0 7.1e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAI97139.1 - 0.0011 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) rve PF00665.21 OAI97148.1 - 3.9e-15 56.0 0.0 9e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI97148.1 - 4.2e-08 32.7 0.0 6.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA_int_endo_N PF02778.9 OAI97153.1 - 0.0045 16.5 0.2 0.0045 16.5 0.2 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain MitMem_reg PF13012.1 OAI97154.1 - 1.6e-19 70.0 0.1 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAI97154.1 - 0.00089 18.9 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PBP1_TM PF14812.1 OAI97158.1 - 0.048 13.9 12.5 2.1 8.7 2.8 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TEX19 PF15553.1 OAI97158.1 - 7.5 6.4 7.9 20 4.9 5.5 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 YL1 PF05764.8 OAI97158.1 - 7.5 6.0 11.7 0.22 11.0 1.6 2.7 3 0 0 3 3 3 0 YL1 nuclear protein UPRTase PF14681.1 OAI97159.1 - 7.7e-79 263.6 0.0 8.9e-79 263.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAI97159.1 - 2.2e-05 24.1 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain OrfB_Zn_ribbon PF07282.6 OAI97163.1 - 8e-16 57.4 0.4 1.5e-15 56.6 0.3 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Bromodomain PF00439.20 OAI97163.1 - 4.1e-14 52.2 0.0 1.5e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Bromodomain HTH_OrfB_IS605 PF12323.3 OAI97163.1 - 4.4e-09 35.5 0.4 1.1e-08 34.2 0.3 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.14 OAI97163.1 - 3.1e-07 30.0 0.0 1.6e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Probable transposase SieB PF14163.1 OAI97163.1 - 0.048 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Superinfection exclusion protein B DZR PF12773.2 OAI97163.1 - 0.054 13.3 0.7 0.11 12.3 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 OAI97163.1 - 0.13 11.4 3.0 0.43 9.8 2.2 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 OAI97163.1 - 0.22 11.0 0.4 14 5.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FYDLN_acid PF09538.5 OAI97163.1 - 0.41 11.2 10.0 0.47 11.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PIF1 PF05970.9 OAI97167.1 - 2e-26 92.8 0.0 5.4e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAI97167.1 - 3.1e-07 30.1 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAI97167.1 - 5.8e-07 29.7 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAI97167.1 - 1.7e-05 22.8 0.1 0.065 10.9 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.1 OAI97167.1 - 0.00028 20.5 0.5 0.0009 18.9 0.2 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_11 PF13086.1 OAI97167.1 - 0.00046 19.8 0.5 0.02 14.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAI97167.1 - 0.0014 18.6 0.0 0.8 9.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.11 OAI97167.1 - 0.0032 16.7 0.1 0.0078 15.4 0.1 1.6 1 0 0 1 1 1 1 PhoH-like protein Mg_chelatase PF01078.16 OAI97167.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 OAI97167.1 - 0.019 14.4 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 OAI97167.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 OAI97167.1 - 0.027 13.9 1.3 3.6 7.0 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 OAI97167.1 - 0.027 14.4 0.5 0.11 12.5 0.2 2.1 2 1 0 2 2 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 OAI97167.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 OAI97167.1 - 0.05 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 OAI97167.1 - 0.051 12.5 0.0 0.095 11.6 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ENOD40 PF08247.6 OAI97167.1 - 0.14 11.9 0.4 0.26 11.1 0.3 1.5 1 0 0 1 1 1 0 ENOD40 protein AAA_32 PF13654.1 OAI97167.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAI97167.1 - 0.16 11.8 0.2 0.4 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAI97167.1 - 0.19 11.4 0.1 0.43 10.2 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase UvrD-helicase PF00580.16 OAI97167.1 - 0.32 10.2 2.1 0.41 9.8 0.3 2.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Daxx PF03344.10 OAI97167.1 - 2.5 6.4 5.0 2.6 6.4 2.7 1.5 2 0 0 2 2 2 0 Daxx Family Nucleoplasmin PF03066.10 OAI97167.1 - 2.7 7.4 6.6 1.5 8.2 2.7 1.9 2 0 0 2 2 2 0 Nucleoplasmin CobT PF06213.7 OAI97167.1 - 3.9 6.5 9.9 29 3.6 0.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Cyclin_N PF00134.18 OAI97174.1 - 6.6e-22 77.4 0.0 2.9e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAI97174.1 - 1.2e-08 34.9 0.0 2.5e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 Cyclin, C-terminal domain MFS_1 PF07690.11 OAI97176.1 - 2e-18 66.2 75.8 8.1e-17 60.9 31.8 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DDE_3 PF13358.1 OAI97184.1 - 8.3e-34 116.4 0.1 1.8e-33 115.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAI97184.1 - 1.1e-09 38.8 0.5 4.1e-09 37.0 0.1 2.2 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 OAI97184.1 - 3e-09 37.0 0.1 5.3e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Winged helix-turn helix DDE_1 PF03184.14 OAI97184.1 - 3.3e-07 29.6 0.0 5.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAI97184.1 - 2.7e-05 24.1 0.6 0.0008 19.4 0.0 2.6 3 0 0 3 3 3 1 Transposase Arg_repressor PF01316.16 OAI97184.1 - 0.00087 18.7 0.0 0.0027 17.2 0.0 1.8 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DDE_Tnp_ISAZ013 PF07592.6 OAI97184.1 - 0.0017 17.1 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain rve PF00665.21 OAI97184.1 - 0.0083 16.2 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain HTH_33 PF13592.1 OAI97184.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF4259 PF14078.1 OAI97184.1 - 0.14 12.6 0.5 0.27 11.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Exo_endo_phos_2 PF14529.1 OAI97189.1 - 0.00015 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Myb_DNA-bind_4 PF13837.1 OAI97193.1 - 0.015 15.3 0.2 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cyclin_N PF00134.18 OAI97199.1 - 2.7e-05 23.7 0.0 0.0021 17.6 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Caldesmon PF02029.10 OAI97201.1 - 0.0012 17.3 12.2 0.002 16.6 8.4 1.3 1 0 0 1 1 1 1 Caldesmon Cgr1 PF03879.9 OAI97201.1 - 0.018 15.2 19.8 0.018 15.2 13.7 1.9 2 0 0 2 2 2 0 Cgr1 family DUF3807 PF12720.2 OAI97201.1 - 0.56 10.3 15.3 0.066 13.3 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Endonuc_Holl PF10107.4 OAI97201.1 - 7.8 6.1 9.3 13 5.4 6.4 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase tRNA-synt_2 PF00152.15 OAI97202.1 - 2.7e-26 92.1 0.0 1.7e-24 86.2 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAI97202.1 - 2.3e-05 24.1 0.0 0.00022 21.0 0.0 2.2 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Tropomyosin PF00261.15 OAI97207.1 - 0.0013 17.9 2.4 0.0013 17.9 1.7 3.0 1 1 1 2 2 2 1 Tropomyosin Pox_A_type_inc PF04508.7 OAI97207.1 - 0.034 13.9 7.7 0.32 10.8 0.2 5.2 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat LPP PF04728.8 OAI97207.1 - 0.93 9.3 8.3 1.6 8.5 0.7 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.2 OAI97207.1 - 1.2 9.0 15.6 0.19 11.5 2.8 3.1 1 1 2 3 3 3 0 Tropomyosin like Fib_alpha PF08702.5 OAI97207.1 - 1.4 9.0 17.3 0.13 12.3 2.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 OAI97207.1 - 2.3 7.8 12.6 0.81 9.3 0.5 2.7 1 1 2 3 3 3 0 Mnd1 family Reo_sigmaC PF04582.7 OAI97207.1 - 2.9 6.9 10.0 0.36 9.9 1.4 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Spc7 PF08317.6 OAI97207.1 - 7.5 5.1 17.3 0.29 9.7 5.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Transposase_21 PF02992.9 OAI97209.1 - 1.5e-17 63.5 0.0 2.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Sigma_reg_C PF13791.1 OAI97209.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator C-terminal AKAP2_C PF15304.1 OAI97209.1 - 0.52 9.8 11.0 0.26 10.8 5.8 1.8 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Ferritin_2 PF13668.1 OAI97215.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain RFamide_26RFa PF11109.3 OAI97218.1 - 0.035 14.0 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 GTP_EFTU PF00009.22 OAI97221.1 - 1.5e-49 168.0 0.0 2.3e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 OAI97221.1 - 8.3e-35 118.9 0.1 1.5e-34 118.0 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 OAI97221.1 - 1.5e-15 56.7 0.1 4.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 OAI97221.1 - 1.4e-05 24.9 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAI97221.1 - 2.6e-05 24.2 0.3 5.2e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAI97221.1 - 0.00024 20.8 0.0 0.00059 19.6 0.0 1.7 1 1 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 OAI97221.1 - 0.003 18.0 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 OAI97221.1 - 0.0035 16.5 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MULE PF10551.4 OAI97225.1 - 2.2e-07 30.9 0.0 0.00084 19.4 0.0 2.6 1 1 1 2 2 2 2 MULE transposase domain Transposase_mut PF00872.13 OAI97225.1 - 0.0089 14.6 0.1 0.017 13.6 0.1 1.5 1 1 0 1 1 1 1 Transposase, Mutator family Het-C PF07217.6 OAI97235.1 - 2.5e-65 220.8 0.1 3e-65 220.6 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SSPI PF14098.1 OAI97235.1 - 0.042 13.7 1.5 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Small, acid-soluble spore protein I DUF1572 PF07609.6 OAI97235.1 - 0.045 13.3 0.1 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) ATP_bind_3 PF01171.15 OAI97242.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family bZIP_1 PF00170.16 OAI97245.1 - 0.0085 16.0 14.7 0.05 13.5 10.1 2.3 1 1 0 1 1 1 1 bZIP transcription factor API5 PF05918.6 OAI97245.1 - 0.05 12.1 3.5 0.088 11.2 2.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Sad1_UNC PF07738.8 OAI97249.1 - 2.7e-11 43.4 0.0 4e-05 23.4 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal DUF2244 PF10003.4 OAI97249.1 - 0.36 10.2 1.5 0.86 8.9 1.0 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF566 PF04484.7 OAI97249.1 - 1.3 8.5 14.3 2.3 7.6 9.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) P33MONOX PF15302.1 OAI97258.1 - 0.039 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 P33 mono-oxygenase eIF-4B PF06273.6 OAI97258.1 - 0.11 11.1 2.4 0.16 10.6 1.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Prenyltransf PF01255.14 OAI97276.1 - 7e-23 80.9 0.0 8.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rer1 PF03248.8 OAI97276.1 - 0.075 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Rer1 family Nop14 PF04147.7 OAI97283.1 - 0.84 7.4 17.4 1.1 7.0 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.22 OAI97288.1 - 1.2e-28 100.0 0.0 2.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI97288.1 - 0.00051 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase UCR_hinge PF02320.11 OAI97288.1 - 0.031 14.2 0.5 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Presenilin PF01080.12 OAI97288.1 - 5.5 5.7 3.7 8.9 5.0 2.5 1.3 1 0 0 1 1 1 0 Presenilin Vps51 PF08700.6 OAI97296.1 - 9.4e-16 57.4 0.4 2e-15 56.4 0.3 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 OAI97296.1 - 5.4e-07 29.5 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Host_attach PF10116.4 OAI97296.1 - 9.6 6.4 8.7 23 5.2 2.0 2.5 2 0 0 2 2 2 0 Protein required for attachment to host cells BAF1_ABF1 PF04684.8 OAI97296.1 - 9.7 4.9 20.5 8.3 5.1 8.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Exo_endo_phos PF03372.18 OAI97299.1 - 7e-05 22.8 3.9 7e-05 22.8 2.7 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DBD_Tnp_Mut PF03108.10 OAI97309.1 - 4.3e-07 29.4 0.0 7.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 MuDR family transposase NODP PF07684.7 OAI97309.1 - 0.27 10.8 2.5 2 8.0 0.2 2.4 2 0 0 2 2 2 0 NOTCH protein RVT_1 PF00078.22 OAI97317.1 - 1.5e-19 70.2 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97317.1 - 1.5e-12 47.6 0.0 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97317.1 - 0.00085 19.7 0.1 0.0042 17.5 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI97317.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 OAI97320.1 - 4.3e-67 225.9 0.0 8.6e-67 225.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97320.1 - 2.5e-50 170.9 0.0 4e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI97320.1 - 0.0048 15.8 0.0 0.01 14.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3337 PF11816.3 OAI97320.1 - 0.21 10.9 3.3 0.33 10.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Hamartin PF04388.7 OAI97320.1 - 2.3 6.8 7.5 3.1 6.3 5.2 1.2 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.4 OAI97320.1 - 9.1 4.3 21.2 9.5 4.3 14.0 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FHA PF00498.21 OAI97322.1 - 0.0012 18.8 0.1 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 FHA domain GCR1_C PF12550.3 OAI97325.1 - 0.0039 17.0 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HSF_DNA-bind PF00447.12 OAI97329.1 - 2.5e-20 72.5 0.7 9.1e-17 61.1 0.0 2.8 3 0 0 3 3 3 2 HSF-type DNA-binding RVT_1 PF00078.22 OAI97332.1 - 3.8e-07 29.6 0.2 6.8e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97333.1 - 1.3e-18 67.2 0.0 7.8e-17 61.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 OAI97333.1 - 0.00021 20.8 1.4 0.00061 19.4 0.2 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_L24e PF01246.15 OAI97342.1 - 9.1e-30 102.3 3.1 9.1e-30 102.3 2.1 1.9 2 1 1 3 3 3 1 Ribosomal protein L24e Flu_M1 PF00598.14 OAI97342.1 - 0.043 13.2 0.6 0.057 12.8 0.4 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) DUF2116 PF09889.4 OAI97342.1 - 3.9 7.3 10.6 4.2 7.2 0.5 2.8 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.27 OAI97343.1 - 9.6e-55 180.6 11.7 4.4e-11 42.2 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat PRP4 PF08799.6 OAI97343.1 - 2.7e-13 48.9 2.7 4.5e-13 48.2 1.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 OAI97343.1 - 4.9e-05 22.5 0.6 0.0082 15.2 0.0 3.4 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 OAI97343.1 - 0.012 13.7 0.4 1 7.4 0.0 2.9 3 1 0 4 4 4 0 Nucleoporin Nup120/160 FHA PF00498.21 OAI97349.1 - 7.1e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain RINT1_TIP1 PF04437.8 OAI97352.1 - 0.075 11.5 0.0 0.093 11.2 0.0 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family RVT_1 PF00078.22 OAI97354.1 - 1.1e-19 70.6 0.0 2.1e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97354.1 - 1.9e-14 53.8 0.1 4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97354.1 - 3.1e-07 30.7 0.1 9.3e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97354.1 - 0.00021 21.0 0.1 0.00076 19.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RuvB_C PF05491.8 OAI97354.1 - 0.041 13.5 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB C-terminus DDE_3 PF13358.1 OAI97354.1 - 0.046 13.4 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 DDE superfamily endonuclease RVP PF00077.15 OAI97354.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Transcrip_reg PF01709.15 OAI97363.1 - 5.8e-32 110.7 0.4 6.5e-32 110.5 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pantoate_ligase PF02569.10 OAI97364.1 - 8.5e-91 303.5 0.0 9.7e-91 303.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Thiolase_C PF02803.13 OAI97365.1 - 1e-51 173.5 0.3 1.6e-51 172.9 0.2 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 OAI97365.1 - 9.9e-34 116.5 0.2 1.4e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain RVT_1 PF00078.22 OAI97368.1 - 4.4e-11 42.5 0.3 8.1e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97368.1 - 2.3e-07 31.2 0.0 2e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97368.1 - 2.3e-07 30.5 0.0 5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAI97368.1 - 3.4e-07 30.2 0.0 7.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 OAI97368.1 - 0.00085 19.1 3.5 0.0017 18.1 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAI97368.1 - 0.0045 17.0 0.1 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Cyclin_N PF00134.18 OAI97371.1 - 0.0014 18.1 0.0 0.0081 15.7 0.0 2.0 2 1 1 3 3 3 1 Cyclin, N-terminal domain Pkinase PF00069.20 OAI97376.1 - 1.2e-27 96.6 0.0 1.2e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97376.1 - 1.7e-12 46.9 0.0 2.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAI97376.1 - 0.00056 19.7 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAI97376.1 - 0.077 11.9 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like MarC PF01914.12 OAI97387.1 - 0.004 16.2 1.2 0.004 16.2 0.9 1.4 2 0 0 2 2 2 1 MarC family integral membrane protein NrfD_2 PF14589.1 OAI97387.1 - 0.022 14.4 0.7 0.025 14.2 0.5 1.0 1 0 0 1 1 1 0 Polysulfide reductase tRNA-synt_1 PF00133.17 OAI97391.1 - 8.1e-08 30.7 0.0 8.3e-08 30.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) RVT_2 PF07727.9 OAI97405.1 - 1.1e-81 273.4 0.0 1.6e-81 272.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97405.1 - 3.6e-24 85.1 0.0 2.9e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAI97405.1 - 7.3e-11 41.6 0.0 1.7e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI97405.1 - 2.8e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI97405.1 - 1.7e-05 24.3 0.0 5.1e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI97405.1 - 3.5e-05 23.2 0.0 8.1e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 OAI97405.1 - 0.0016 18.3 5.7 0.004 17.0 4.0 1.8 1 0 0 1 1 1 1 Zinc knuckle UBN2_3 PF14244.1 OAI97405.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVP PF00077.15 OAI97405.1 - 0.061 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.1 OAI97405.1 - 0.16 11.4 2.7 0.36 10.3 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Nucleoporin_FG PF13634.1 OAI97409.1 - 0.083 13.1 2.2 0.14 12.4 1.5 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region RVT_1 PF00078.22 OAI97410.1 - 6.4e-32 110.6 0.0 1.2e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAM2 PF07145.10 OAI97410.1 - 0.88 9.2 8.8 0.045 13.2 1.1 2.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DUF3500 PF12006.3 OAI97411.1 - 0.17 10.8 0.2 0.33 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) MCLC PF05934.6 OAI97411.1 - 0.65 8.2 2.8 0.97 7.6 2.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) T3SS_LEE_assoc PF13327.1 OAI97413.1 - 0.012 15.1 0.1 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system subunit CFTR_R PF14396.1 OAI97413.1 - 0.13 11.5 0.5 0.22 10.8 0.3 1.3 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain HTH_23 PF13384.1 OAI97422.1 - 0.025 14.2 0.0 0.08 12.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 OAI97422.1 - 0.028 14.4 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_17 PF12728.2 OAI97422.1 - 0.05 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DEC-1_N PF04625.8 OAI97422.1 - 0.74 8.4 7.9 0.66 8.5 4.4 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Pkinase PF00069.20 OAI97429.1 - 9.9e-41 139.5 0.0 1.3e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI97429.1 - 2.9e-18 65.8 0.0 4.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAI97429.1 - 0.027 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 OAI97429.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RVT_2 PF07727.9 OAI97441.1 - 9.8e-71 237.5 0.0 1.4e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97441.1 - 2.7e-23 82.3 0.2 1.2e-22 80.2 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAI97441.1 - 5.7e-10 38.6 21.3 0.011 15.6 1.5 4.7 4 0 0 4 4 4 4 Zinc knuckle gag_pre-integrs PF13976.1 OAI97441.1 - 2.3e-08 33.5 1.2 1.7e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI97441.1 - 0.018 14.5 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain Pol_alpha_B_N PF08418.5 OAI97441.1 - 0.21 11.0 0.3 1.5 8.3 0.1 2.1 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Myb_DNA-bind_4 PF13837.1 OAI97443.1 - 0.0099 15.9 0.8 0.026 14.6 0.0 2.2 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Cytochrom_NNT PF03264.9 OAI97443.1 - 0.63 9.4 9.0 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region DDE_Tnp_4 PF13359.1 OAI97444.1 - 3.1e-25 88.6 0.0 4.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 OAI97444.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Phage_integrase PF00589.17 OAI97448.1 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Pentapeptide PF00805.17 OAI97448.1 - 0.14 11.4 0.1 0.3 10.3 0.1 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) YkyA PF10368.4 OAI97449.1 - 1.5 8.1 8.4 2.2 7.5 5.8 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Asp PF00026.18 OAI97461.1 - 8.4e-20 71.2 0.0 1.3e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VWA_2 PF13519.1 OAI97462.1 - 9.5e-08 32.3 0.2 1.2e-07 32.0 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain RVT_1 PF00078.22 OAI97469.1 - 2.8e-25 88.9 0.1 7.2e-25 87.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97469.1 - 9.8e-21 74.0 0.0 3.1e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 OAI97469.1 - 9.3e-06 25.3 0.0 3.6e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI97469.1 - 1.6e-05 25.3 0.0 4.4e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 OAI97469.1 - 0.079 12.9 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAI97470.1 - 1.9e-12 47.1 0.3 9.6e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein Herpes_BLRF2 PF05812.7 OAI97470.1 - 0.013 15.3 1.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF2205 PF10224.4 OAI97470.1 - 0.065 12.8 0.9 0.15 11.6 0.7 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) IP_trans PF02121.13 OAI97470.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein MAGE_N PF12440.3 OAI97470.1 - 0.79 10.0 5.2 4.8 7.5 0.3 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Metallophos_2 PF12850.2 OAI97472.1 - 0.085 12.6 0.0 0.27 11.0 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DAO PF01266.19 OAI97481.1 - 7.3e-48 163.2 0.4 1.2e-47 162.6 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase EF-hand_7 PF13499.1 OAI97481.1 - 1.8e-06 27.9 0.3 3.8e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.19 OAI97481.1 - 7.1e-06 25.1 6.6 9.5e-05 21.4 4.6 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 OAI97481.1 - 7.2e-06 25.3 0.6 2.1e-05 23.8 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAI97481.1 - 4.3e-05 23.4 0.3 0.0064 16.3 0.1 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAI97481.1 - 0.00019 20.4 0.1 0.00072 18.6 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAI97481.1 - 0.0012 18.5 0.4 0.0041 16.8 0.1 2.1 2 0 0 2 2 1 1 EF-hand domain FAD_binding_3 PF01494.14 OAI97481.1 - 0.0029 16.7 0.2 1.5 7.7 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain EF-hand_5 PF13202.1 OAI97481.1 - 0.0096 15.2 0.4 0.022 14.0 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 OAI97481.1 - 0.019 14.5 0.7 0.35 10.5 0.1 3.2 3 1 1 4 4 4 0 EF-hand domain pair 3HCDH_N PF02737.13 OAI97481.1 - 0.024 14.2 0.2 0.057 13.0 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 OAI97481.1 - 0.028 13.2 0.5 0.15 10.9 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 OAI97481.1 - 0.031 14.3 0.2 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI97481.1 - 0.13 12.6 0.7 0.35 11.3 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.4 OAI97481.1 - 0.21 11.6 0.0 0.48 10.4 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_8 PF13450.1 OAI97481.1 - 1.6 8.8 5.5 0.25 11.4 0.4 2.3 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain DNA_pol_viral_C PF00336.13 OAI97484.1 - 0.0079 15.4 0.1 0.019 14.2 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Spt5_N PF11942.3 OAI97497.1 - 0.057 14.0 5.2 0.057 14.0 3.6 3.1 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal LZ_Tnp_IS66 PF13007.2 OAI97497.1 - 0.88 10.2 3.9 0.39 11.4 0.8 1.7 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain BTV_NS2 PF04514.7 OAI97497.1 - 1 8.1 9.3 1.1 8.0 6.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.6 OAI97497.1 - 6.9 5.2 8.7 8 5.0 6.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Lectin_N PF03954.9 OAI97506.1 - 0.0016 17.8 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Bacillus_HBL PF05791.6 OAI97506.1 - 0.015 14.6 0.1 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF869 PF05911.6 OAI97506.1 - 0.091 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) CK2S PF15011.1 OAI97510.1 - 0.028 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF2281 PF10047.4 OAI97510.1 - 0.029 14.6 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) rve PF00665.21 OAI97511.1 - 1.7e-11 44.2 0.0 4.8e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI97511.1 - 7.5e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.26 OAI97515.1 - 4.3e-11 42.5 0.0 9.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI97515.1 - 1.9e-05 24.2 0.0 0.00012 21.6 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase CsoSCA PF08936.5 OAI97515.1 - 0.16 10.3 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DUF2969 PF11184.3 OAI97515.1 - 0.17 12.0 0.1 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) PAT1 PF09770.4 OAI97521.1 - 0.35 9.0 12.4 0.31 9.2 8.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 OAI97521.1 - 4.6 5.8 23.2 5.8 5.5 16.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3043 PF11241.3 OAI97521.1 - 6.4 6.3 6.5 29 4.1 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DDE_Tnp_4 PF13359.1 OAI97522.1 - 2.1e-26 92.3 0.0 2.7e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI97522.1 - 2e-09 37.1 0.0 2.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI97522.1 - 0.0013 18.2 0.1 0.0032 17.0 0.1 1.7 1 1 0 1 1 1 1 Transposase DDE domain DUF3322 PF11795.3 OAI97526.1 - 2.3 7.8 5.7 1.4 8.5 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) WD40 PF00400.27 OAI97533.1 - 3.3e-27 93.3 9.4 1.3e-07 31.1 0.1 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 OAI97533.1 - 5.5e-11 41.3 2.0 0.00083 17.6 0.1 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAI97533.1 - 0.0063 15.3 0.0 0.43 9.2 0.0 2.8 2 1 0 3 3 3 1 Nup133 N terminal like Cortex-I_coil PF09304.5 OAI97533.1 - 0.26 11.3 3.1 0.48 10.4 2.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF605 PF04652.11 OAI97539.1 - 0.72 9.1 12.5 0.86 8.9 8.7 1.0 1 0 0 1 1 1 0 Vta1 like Carb_anhydrase PF00194.16 OAI97542.1 - 0.12 11.3 0.4 0.41 9.5 0.3 1.8 1 1 0 1 1 1 0 Eukaryotic-type carbonic anhydrase RVT_2 PF07727.9 OAI97545.1 - 1.3e-87 292.8 0.0 1.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97545.1 - 2.3e-19 69.6 0.0 1.7e-18 66.8 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.1 OAI97545.1 - 5.9e-07 29.0 0.2 1.3e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 OAI97546.1 - 8.1e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97546.1 - 0.00021 21.0 5.9 0.00049 19.9 4.1 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 OAI97546.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_2 PF07727.9 OAI97549.1 - 4.7e-88 294.3 0.0 6.6e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97549.1 - 1.8e-19 69.9 0.0 6.6e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAI97549.1 - 0.00034 20.1 0.0 0.00072 19.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF1880 PF08976.6 OAI97550.1 - 0.0088 16.1 0.2 0.022 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1880) FHA PF00498.21 OAI97553.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain Ank_2 PF12796.2 OAI97557.1 - 1.2e-12 47.9 0.0 2.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAI97557.1 - 1.1e-11 44.9 0.3 4.5e-07 30.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAI97557.1 - 2.4e-08 33.3 0.1 1.7e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 OAI97557.1 - 7.8e-07 29.1 0.3 2.9e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAI97557.1 - 2.1e-06 27.3 0.0 0.00017 21.5 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Methyltransf_18 PF12847.2 OAI97557.1 - 0.00031 21.2 0.0 0.0013 19.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAI97557.1 - 0.0023 18.4 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAI97557.1 - 0.0041 17.9 0.0 0.051 14.3 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain TB2_DP1_HVA22 PF03134.14 OAI97558.1 - 1.7e-05 24.4 0.1 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GTP_EFTU PF00009.22 OAI97559.1 - 0.03 13.7 0.0 0.061 12.7 0.0 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain zf-CCHC_3 PF13917.1 OAI97559.1 - 0.034 13.8 0.1 0.086 12.5 0.1 1.7 2 0 0 2 2 2 0 Zinc knuckle Clp_N PF02861.15 OAI97560.1 - 0.069 13.0 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Clp amino terminal domain BAG PF02179.11 OAI97564.1 - 6.6e-13 48.5 0.4 4.3e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 OAI97564.1 - 5.3e-08 32.1 0.0 9.3e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TarH PF02203.10 OAI97564.1 - 0.16 11.8 1.4 0.32 10.8 1.0 1.6 1 0 0 1 1 1 0 Tar ligand binding domain homologue Thioredoxin_8 PF13905.1 OAI97565.1 - 1.7e-10 40.8 0.1 1e-09 38.3 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 OAI97565.1 - 0.0011 18.4 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAI97565.1 - 0.047 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Integrase_AP2 PF14657.1 OAI97567.1 - 0.17 11.6 3.1 0.43 10.4 2.2 1.7 1 1 0 1 1 1 0 AP2-like DNA-binding integrase domain G3P_antiterm PF04309.7 OAI97568.1 - 0.066 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Zot PF05707.7 OAI97569.1 - 1.1e-24 87.0 0.0 1.4e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AMP-binding PF00501.23 OAI97571.1 - 6.7e-168 558.3 0.1 4.8e-86 288.7 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 OAI97571.1 - 6.1e-37 127.0 0.0 9.3e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 OAI97571.1 - 7.8e-11 42.0 0.0 2.6e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAI97571.1 - 1.1e-06 29.4 0.5 0.0016 19.3 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Peptidase_S10 PF00450.17 OAI97575.1 - 1e-73 248.8 0.0 1.4e-73 248.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAI97575.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA PF00004.24 OAI97576.1 - 2.2e-41 141.1 0.0 3.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAI97576.1 - 1.4e-07 31.6 0.3 6.6e-05 23.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAI97576.1 - 4.3e-06 26.7 0.0 6.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAI97576.1 - 1.7e-05 23.9 0.0 3.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 OAI97576.1 - 5.1e-05 23.3 0.1 0.00057 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAI97576.1 - 0.0002 21.1 0.5 0.0019 17.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAI97576.1 - 0.0004 19.5 0.0 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAI97576.1 - 0.00071 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAI97576.1 - 0.0011 18.3 0.6 0.37 10.1 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.6 OAI97576.1 - 0.0016 18.0 0.1 0.0055 16.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 OAI97576.1 - 0.0018 17.4 0.1 0.092 11.8 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_17 PF13207.1 OAI97576.1 - 0.0026 18.5 0.4 0.0044 17.8 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAI97576.1 - 0.0033 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI97576.1 - 0.004 16.8 0.3 0.0078 15.9 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAI97576.1 - 0.0053 17.0 0.1 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAI97576.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 OAI97576.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 OAI97576.1 - 0.019 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 OAI97576.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAI97576.1 - 0.02 14.5 0.2 0.24 11.0 0.1 2.2 1 1 1 2 2 2 0 NACHT domain NB-ARC PF00931.17 OAI97576.1 - 0.022 13.6 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 OAI97576.1 - 0.024 13.8 0.2 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 OAI97576.1 - 0.036 14.2 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 OAI97576.1 - 0.04 12.8 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 OAI97576.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Histone PF00125.19 OAI97576.1 - 0.071 13.2 0.2 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 AAA_24 PF13479.1 OAI97576.1 - 0.079 12.5 0.3 0.17 11.4 0.1 1.6 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 OAI97576.1 - 0.11 11.9 0.2 0.86 9.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 OAI97576.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad60-SLD PF11976.3 OAI97578.1 - 0.038 13.6 0.4 26 4.6 0.0 4.3 5 0 0 5 5 5 0 Ubiquitin-2 like Rad60 SUMO-like PBP_sp32 PF07222.7 OAI97579.1 - 0.13 11.4 4.1 0.16 11.1 2.9 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 APG6 PF04111.7 OAI97579.1 - 0.75 8.7 5.8 0.78 8.7 4.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PDR_assoc PF08370.6 OAI97583.1 - 0.18 11.3 0.9 0.36 10.3 0.6 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated zf-C2H2_4 PF13894.1 OAI97583.1 - 3.2 8.2 6.0 0.46 10.9 1.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Retrotrans_gag PF03732.12 OAI97585.1 - 8.9e-16 57.7 2.4 1.9e-15 56.6 1.7 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI97585.1 - 0.037 13.9 3.0 0.057 13.3 2.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAI97586.1 - 1.3e-20 73.6 0.1 7.9e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97586.1 - 3.9e-15 56.0 0.0 1.3e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVP_2 PF08284.6 OAI97586.1 - 2.1e-08 34.1 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.19 OAI97586.1 - 4.1e-07 29.5 0.0 8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 OAI97586.1 - 0.0034 17.1 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI97586.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Ilar_coat PF01787.11 OAI97590.1 - 0.28 10.7 3.2 0.54 9.8 2.2 1.5 1 0 0 1 1 1 0 Ilarvirus coat protein PAT1 PF09770.4 OAI97596.1 - 1.4 7.0 22.2 1.6 6.8 15.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kisspeptin PF15152.1 OAI97596.1 - 1.6 9.4 4.2 15 6.3 0.1 2.6 1 1 1 2 2 2 0 Kisspeptin BAF1_ABF1 PF04684.8 OAI97596.1 - 2.6 6.8 8.2 3.2 6.5 5.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3028 PF11229.3 OAI97599.1 - 0.038 12.2 0.4 0.052 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) FHA PF00498.21 OAI97600.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 FHA domain EF1_GNE PF00736.14 OAI97604.1 - 1.3e-31 108.1 2.0 2.4e-31 107.2 1.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 OAI97604.1 - 4.3e-13 49.1 6.4 4.3e-13 49.1 4.5 2.8 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 OAI97604.1 - 6.5e-05 23.3 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAI97604.1 - 7.9e-05 22.4 0.3 0.0017 18.1 0.2 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 OAI97604.1 - 0.0092 15.7 2.8 0.014 15.1 1.9 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GST_C PF00043.20 OAI97604.1 - 0.017 15.0 0.0 0.075 13.0 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Exonuc_VII_S PF02609.11 OAI97604.1 - 0.27 11.0 1.6 13 5.6 0.1 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Stm1_N PF09598.5 OAI97604.1 - 0.49 11.1 9.3 0.32 11.7 0.5 2.5 2 0 0 2 2 2 0 Stm1 CLTH PF10607.4 OAI97605.1 - 1.1e-16 60.8 0.0 3.2e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Brr6_like_C_C PF10104.4 OAI97614.1 - 5.1e-08 32.5 0.5 6.6e-08 32.1 0.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF842 PF05811.8 OAI97614.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Dimer_Tnp_hAT PF05699.9 OAI97618.1 - 1.6e-07 30.8 0.0 5.4e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RecO_C PF02565.10 OAI97618.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Recombination protein O C terminal Het-C PF07217.6 OAI97626.1 - 6.2e-107 358.2 0.0 7.4e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.3 OAI97626.1 - 0.0083 16.1 0.4 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function VcgC/VcgE (DUF2780) Het-C PF07217.6 OAI97628.1 - 1.3e-31 109.4 1.0 1.4e-31 109.3 0.7 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF1572 PF07609.6 OAI97628.1 - 0.0037 16.8 0.1 0.0041 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1572) AdoMet_dc PF02675.10 OAI97628.1 - 0.029 14.2 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase DUF3387 PF11867.3 OAI97628.1 - 0.068 12.1 0.1 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) MFS_1 PF07690.11 OAI97630.1 - 1.4e-22 79.9 24.3 1.5e-22 79.8 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI97630.1 - 3.6e-08 32.4 12.0 4.7e-08 32.0 8.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DsbB PF02600.11 OAI97631.1 - 6e-25 87.8 16.8 7.6e-25 87.5 11.7 1.1 1 0 0 1 1 1 1 Disulfide bond formation protein DsbB TPPK_C PF12555.3 OAI97631.1 - 0.034 13.8 2.7 0.034 13.8 1.9 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal DUF360 PF04020.8 OAI97631.1 - 0.17 12.2 10.7 0.31 11.4 5.6 2.2 2 1 0 2 2 2 0 Membrane protein of unknown function Caveolin PF01146.12 OAI97631.1 - 0.7 9.4 3.1 1.1 8.7 2.2 1.3 1 0 0 1 1 1 0 Caveolin NfeD PF01957.13 OAI97631.1 - 2.1 8.4 5.5 1.1 9.3 2.1 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding ATP-grasp_4 PF13535.1 OAI97632.1 - 1.4e-38 132.4 0.0 4.7e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 OAI97632.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DUF1028 PF06267.7 OAI97632.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) ATPgrasp_Ter PF15632.1 OAI97632.1 - 0.091 11.4 0.0 0.15 10.7 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Aminotran_5 PF00266.14 OAI97633.1 - 1e-34 119.9 0.0 2e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAI97633.1 - 0.00018 20.5 0.0 0.0032 16.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 OAI97633.1 - 0.027 13.5 0.1 0.062 12.3 0.1 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family EamA PF00892.15 OAI97634.1 - 2.2e-21 76.2 40.3 1.5e-14 54.1 9.6 2.7 1 1 2 3 3 3 2 EamA-like transporter family TPT PF03151.11 OAI97634.1 - 9.5e-05 22.0 21.6 0.0087 15.7 2.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 OAI97634.1 - 0.0006 19.9 32.4 0.019 15.1 7.1 3.1 1 1 2 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 OAI97634.1 - 1.1 8.0 17.3 0.21 10.4 3.1 2.3 1 1 1 2 2 2 0 UAA transporter family Dimer_Tnp_hAT PF05699.9 OAI97636.1 - 2e-16 59.3 0.0 5.1e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cytochrom_B558a PF05038.8 OAI97640.1 - 0.22 11.1 0.1 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit rve PF00665.21 OAI97643.1 - 1.4e-20 73.5 0.0 4.7e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag-asp_proteas PF13975.1 OAI97643.1 - 4.1e-09 36.1 0.1 1.5e-08 34.3 0.1 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI97643.1 - 4.8e-08 33.4 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 OAI97643.1 - 0.00023 21.1 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease MIP-T3 PF10243.4 OAI97643.1 - 0.0024 16.4 6.7 0.0036 15.8 4.7 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RVP PF00077.15 OAI97643.1 - 0.0078 16.1 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 OAI97643.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GBP_PSP PF02425.10 OAI97643.1 - 0.049 13.1 0.9 0.84 9.2 0.0 2.4 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Asp_protease PF09668.5 OAI97643.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TFIIF_alpha PF05793.7 OAI97643.1 - 2.2 6.5 21.6 3.7 5.7 15.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Chromo PF00385.19 OAI97645.1 - 3.4e-08 33.0 4.6 7.1e-08 32.0 3.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAI97645.1 - 1.3e-07 31.2 0.0 2.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain Ribosomal_60s PF00428.14 OAI97645.1 - 0.75 10.2 12.2 2.3 8.6 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cyclin_N PF00134.18 OAI97646.1 - 1.3e-09 37.7 0.0 3.9e-09 36.1 0.0 1.9 1 1 1 2 2 2 1 Cyclin, N-terminal domain eIF3_subunit PF08597.5 OAI97649.1 - 9.3 5.7 16.4 24 4.3 11.4 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit RVT_3 PF13456.1 OAI97650.1 - 0.11 12.3 0.8 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase-like Phage_integrase PF00589.17 OAI97651.1 - 0.00086 19.0 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAI97651.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain CK2S PF15011.1 OAI97665.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate rve PF00665.21 OAI97678.1 - 1.3e-18 67.1 0.0 3.3e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI97678.1 - 1.1e-15 57.5 0.0 2.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAI97678.1 - 0.00023 20.6 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAI97678.1 - 0.0017 18.1 1.9 0.0017 18.1 1.3 2.2 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAI97678.1 - 0.23 11.1 1.7 0.71 9.5 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle Inositol_P PF00459.20 OAI97686.1 - 2.1e-59 201.0 0.0 2.5e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family PALP PF00291.20 OAI97687.1 - 5.2e-43 147.4 0.0 3.7e-41 141.3 0.0 2.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1049 PF06305.6 OAI97687.1 - 0.0041 16.5 0.8 0.027 13.9 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1049) ADH_zinc_N PF00107.21 OAI97687.1 - 0.057 12.9 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Tim17 PF02466.14 OAI97687.1 - 0.099 12.6 1.8 12 5.9 0.2 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family SH3_9 PF14604.1 OAI97689.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAI97689.1 - 6.6e-08 31.8 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAI97689.1 - 4.3e-06 26.1 0.0 7.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain NmrA PF05368.8 OAI97690.1 - 6.4e-18 64.8 0.0 7.6e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAI97690.1 - 1.3e-09 38.3 0.0 1.5e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAI97690.1 - 9.4e-09 34.7 0.0 1.1e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 OAI97690.1 - 7.4e-05 22.7 0.0 9.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 OAI97690.1 - 0.0008 19.5 0.0 0.00093 19.3 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 OAI97690.1 - 0.0017 18.2 0.0 0.0024 17.7 0.0 1.3 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAI97690.1 - 0.004 17.5 0.2 0.0074 16.6 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAI97690.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 OAI97690.1 - 0.019 15.2 0.0 0.024 14.8 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 OAI97690.1 - 0.024 13.8 0.0 0.041 13.0 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 OAI97690.1 - 0.025 14.8 0.1 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ApbA PF02558.11 OAI97690.1 - 0.028 13.8 0.0 0.033 13.6 0.0 1.2 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.14 OAI97690.1 - 0.038 12.6 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CPSase_L_chain PF00289.17 OAI97690.1 - 0.04 14.0 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain DUF2613 PF11021.3 OAI97690.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) FTCD_C PF04961.7 OAI97693.1 - 2 7.8 8.1 2.6 7.4 5.6 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase UBN2_2 PF14227.1 OAI97694.1 - 7.9e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI97694.1 - 1.4e-05 24.6 0.0 4.4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAI97694.1 - 1.4e-05 24.7 9.3 0.02 14.8 0.5 2.6 2 0 0 2 2 2 2 Zinc knuckle UBN2_3 PF14244.1 OAI97694.1 - 9.4e-05 22.0 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAI97694.1 - 0.0005 19.8 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.1 OAI97694.1 - 0.021 14.5 8.0 0.11 12.2 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAI97694.1 - 0.052 13.0 7.4 0.44 10.0 0.6 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAI97694.1 - 1 9.1 9.0 1.5 8.5 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.24 OAI97697.1 - 1.5e-41 141.7 0.4 3e-41 140.7 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI97697.1 - 1.6e-29 101.5 0.1 3.8e-29 100.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAI97697.1 - 0.0059 16.3 0.2 0.014 15.1 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF1253 PF06862.7 OAI97697.1 - 0.0075 14.7 0.0 0.027 12.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) SecA_DEAD PF07517.9 OAI97697.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain ResIII PF04851.10 OAI97697.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_23 PF13489.1 OAI97698.1 - 9.2e-13 48.2 0.0 2.6e-12 46.7 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI97698.1 - 4.1e-09 37.0 0.0 6.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAI97698.1 - 1.5e-06 28.5 0.0 7.7e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI97698.1 - 1.9e-06 28.2 0.0 3.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAI97698.1 - 1.9e-06 28.1 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAI97698.1 - 1.9e-05 24.2 0.0 5.6e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAI97698.1 - 0.00026 20.9 0.0 0.00095 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAI97698.1 - 0.0015 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 OAI97698.1 - 0.037 13.4 1.2 0.19 11.0 0.0 2.2 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW MTS PF05175.9 OAI97698.1 - 0.11 11.8 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain DUF3449 PF11931.3 OAI97699.1 - 1.2e-70 237.0 0.4 6.6e-70 234.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) zf-met PF12874.2 OAI97699.1 - 0.00039 20.5 4.1 0.0041 17.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAI97699.1 - 0.0017 18.4 8.9 0.0052 16.8 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 OAI97699.1 - 0.0033 17.5 0.8 2.5 8.2 0.1 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SF3a60_bindingd PF12108.3 OAI97699.1 - 0.072 12.6 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DUF2175 PF09943.4 OAI97699.1 - 8.4 6.5 7.8 6 6.9 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Phage_integrase PF00589.17 OAI97703.1 - 0.0034 17.0 0.0 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAI97704.1 - 0.0085 15.4 0.1 0.02 14.2 0.1 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.1 OAI97705.1 - 3.8 7.2 9.9 0.44 10.2 2.5 2.2 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 OAI97715.1 - 1.7e-05 24.3 0.0 2.1e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI97720.1 - 1.1e-16 60.8 0.0 3.2e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97720.1 - 1.6e-05 25.2 0.0 5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97720.1 - 0.0064 16.2 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 OAI97720.1 - 0.034 14.2 0.0 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain RVP PF00077.15 OAI97720.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAI97725.1 - 2e-16 59.9 0.0 3.3e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97726.1 - 7.4e-16 58.3 0.0 2.4e-15 56.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 OAI97727.1 - 0.088 12.8 0.3 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein Peroxidase_2 PF01328.12 OAI97732.1 - 2.7e-14 52.5 0.1 6.3e-14 51.3 0.1 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 Vac_Fusion PF02346.11 OAI97744.1 - 0.11 11.9 0.2 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Chordopoxvirus fusion protein CcmD PF04995.9 OAI97747.1 - 8.9 6.1 15.5 1.4 8.7 0.2 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Molydop_binding PF01568.16 OAI97752.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain UBN2 PF14223.1 OAI97756.1 - 4.7e-10 39.2 1.3 4.7e-10 39.2 0.9 1.5 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97756.1 - 3.5e-06 26.6 5.3 6.4e-06 25.8 3.7 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 OAI97756.1 - 0.015 14.8 0.2 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 OAI97756.1 - 0.047 13.3 2.9 0.15 11.7 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle API5 PF05918.6 OAI97756.1 - 0.058 11.8 0.5 0.086 11.3 0.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RVT_2 PF07727.9 OAI97757.1 - 3.3e-84 281.6 0.0 4.4e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAI97757.1 - 0.0087 15.4 0.0 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SART-1 PF03343.8 OAI97766.1 - 1.9e-105 353.5 58.6 2.2e-105 353.3 40.6 1.0 1 0 0 1 1 1 1 SART-1 family AMP-binding PF00501.23 OAI97767.1 - 4.8e-19 68.0 0.2 2.2e-17 62.5 0.1 2.1 2 0 0 2 2 2 2 AMP-binding enzyme RVT_1 PF00078.22 OAI97771.1 - 7.3e-17 61.4 0.0 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97771.1 - 5.5e-16 58.7 0.0 1.4e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97771.1 - 3.2e-06 27.5 0.0 3.9e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97771.1 - 0.0018 18.0 0.1 0.0055 16.5 0.1 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease FliD_N PF02465.13 OAI97771.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Reo_sigmaC PF04582.7 OAI97771.1 - 0.3 10.2 0.0 0.65 9.1 0.0 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cyclin_N PF00134.18 OAI97774.1 - 8.1e-16 57.7 0.0 1.2e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cep57_MT_bd PF06657.8 OAI97774.1 - 0.031 14.2 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 RVT_1 PF00078.22 OAI97779.1 - 1e-17 64.2 0.0 2.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97779.1 - 5.6e-14 52.2 0.0 1.4e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97779.1 - 0.0026 18.1 0.1 0.0078 16.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI97779.1 - 0.0042 16.9 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Transposase_21 PF02992.9 OAI97782.1 - 3e-13 49.3 0.0 4.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Transposase_21 PF02992.9 OAI97783.1 - 2.4e-07 30.0 0.0 5.5e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAI97783.1 - 0.00021 20.7 0.1 0.0004 19.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) OAD_gamma PF04277.8 OAI97786.1 - 0.58 10.5 3.6 0.57 10.5 0.4 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sporozoite_P67 PF05642.6 OAI97786.1 - 0.76 7.5 3.2 1 7.1 2.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.14 OAI97791.1 - 7e-57 193.0 0.0 9.4e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain MHCassoc_trimer PF08831.5 OAI97791.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Redoxin PF08534.5 OAI97791.1 - 0.15 11.6 0.0 24 4.4 0.0 2.8 2 1 1 3 3 3 0 Redoxin Abhydrolase_6 PF12697.2 OAI97792.1 - 1.3e-34 120.0 0.1 1.9e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI97792.1 - 7.9e-18 64.8 0.0 2e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAI97792.1 - 9.2e-14 51.4 0.0 5.6e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 OAI97792.1 - 0.011 14.2 0.0 0.019 13.4 0.0 1.5 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 OAI97792.1 - 0.017 14.9 0.0 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAI97792.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAI97792.1 - 0.053 13.1 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 OAI97792.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative esterase Amidohydro_1 PF01979.15 OAI97793.1 - 2e-17 63.8 0.0 2.5e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 OAI97793.1 - 1.9e-08 34.7 0.5 3.1e-08 34.0 0.4 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 OAI97793.1 - 6.1e-07 29.0 0.2 7.2e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family rve PF00665.21 OAI97798.1 - 8.5e-15 54.9 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI97798.1 - 1.5e-11 44.0 0.0 4.8e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97799.1 - 1.2e-06 28.9 0.0 2.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI97799.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI97799.1 - 0.08 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAI97802.1 - 7.6e-19 67.9 0.0 1.6e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97802.1 - 2.1e-14 53.6 0.0 4.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF1444 PF07285.6 OAI97802.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) HlyD PF00529.15 OAI97803.1 - 0.016 14.5 0.6 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Retrotrans_gag PF03732.12 OAI97803.1 - 0.069 13.2 0.2 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Antigen_Bd37 PF11641.3 OAI97803.1 - 0.17 11.1 0.1 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein FUSC PF04632.7 OAI97803.1 - 0.67 8.3 10.5 0.63 8.3 3.0 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family PMT PF02366.13 OAI97806.1 - 3.9e-76 255.6 15.0 7.5e-76 254.7 10.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAI97806.1 - 1.5e-11 44.1 4.1 3.5e-10 39.7 1.6 2.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 OAI97806.1 - 1.6e-06 28.1 10.4 1.6e-06 28.1 7.2 2.7 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase UBN2 PF14223.1 OAI97810.1 - 4.2e-06 26.5 0.0 2.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI97810.1 - 0.018 14.9 4.8 0.038 13.9 3.3 1.6 1 0 0 1 1 1 0 Zinc knuckle UBN2_2 PF14227.1 OAI97810.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 OAI97811.1 - 1e-86 289.9 0.0 1.4e-86 289.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97811.1 - 1.8e-21 76.4 0.5 1.1e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAI97811.1 - 4.4e-06 26.2 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAI97811.1 - 0.01 15.3 1.7 0.075 12.5 0.2 3.0 2 1 0 2 2 2 0 Integrase core domain RVT_1 PF00078.22 OAI97811.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NIT PF08376.5 OAI97811.1 - 0.62 9.5 3.6 0.45 9.9 0.5 2.1 2 0 0 2 2 2 0 Nitrate and nitrite sensing Helicase_C PF00271.26 OAI97815.1 - 1.6e-10 40.6 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2 PF00096.21 OAI97815.1 - 3.4e-05 23.9 5.8 0.16 12.3 1.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type DEAD PF00270.24 OAI97815.1 - 0.00012 21.6 0.0 0.00033 20.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2_4 PF13894.1 OAI97815.1 - 0.0016 18.6 4.4 0.47 10.9 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Retrotrans_gag PF03732.12 OAI97820.1 - 0.019 15.0 0.1 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF4455 PF14643.1 OAI97820.1 - 0.19 10.3 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) adh_short_C2 PF13561.1 OAI97825.1 - 0.00041 20.1 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.22 OAI97828.1 - 2.8e-17 62.8 0.0 5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97828.1 - 0.00027 21.3 0.0 0.00076 19.9 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 OAI97828.1 - 0.0062 16.5 0.4 0.017 15.1 0.2 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein RVP PF00077.15 OAI97828.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease NT5C PF06941.7 OAI97828.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF70 PF01901.11 OAI97828.1 - 5.1 6.0 2.6 7.7 5.4 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 FA_hydroxylase PF04116.8 OAI97829.1 - 9.3e-05 22.8 2.7 0.00011 22.5 1.9 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Spt5_N PF11942.3 OAI97829.1 - 0.00026 21.5 8.0 0.00026 21.5 5.5 3.3 3 1 0 3 3 3 2 Spt5 transcription elongation factor, acidic N-terminal Zip PF02535.17 OAI97829.1 - 0.00068 18.7 0.8 0.00083 18.4 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ycf1 PF05758.7 OAI97829.1 - 0.049 11.3 0.9 0.054 11.2 0.6 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 OAI97829.1 - 1.3 7.8 10.3 1.8 7.2 7.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PGA2 PF07543.7 OAI97829.1 - 2.8 7.7 17.3 4.2 7.1 12.0 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Astro_capsid PF03115.9 OAI97829.1 - 9 4.4 8.0 10 4.2 5.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor PCEMA1 PF07418.6 OAI97832.1 - 0.0064 15.8 0.2 0.009 15.4 0.2 1.3 1 0 0 1 1 1 1 Acidic phosphoprotein precursor PCEMA1 DUF4581 PF15167.1 OAI97833.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) HSP70 PF00012.15 OAI97838.1 - 3.5e-07 28.5 0.0 4.8e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein DUF3987 PF13148.1 OAI97846.1 - 0.061 11.8 8.4 0.12 10.9 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2782 PF11191.3 OAI97846.1 - 0.4 10.6 8.5 0.05 13.5 1.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2782) DEAD PF00270.24 OAI97850.1 - 2.5e-14 53.1 0.0 4.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI97850.1 - 7.6e-06 25.7 0.1 5.7e-05 22.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1682 PF07946.9 OAI97850.1 - 0.37 9.5 9.3 0.72 8.6 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2452 PF10504.4 OAI97854.1 - 0.014 14.6 2.0 0.028 13.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) ETF_QO PF05187.8 OAI97854.1 - 0.1 12.5 0.6 0.24 11.4 0.4 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase DUF883 PF05957.8 OAI97854.1 - 3.1 8.2 19.7 6.1 7.3 7.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Phage_integrase PF00589.17 OAI97859.1 - 9.6e-07 28.6 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RNase_H PF00075.19 OAI97859.1 - 0.00049 20.4 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAI97859.1 - 0.029 14.1 0.1 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like RHD3 PF05879.7 OAI97863.1 - 8.7e-13 47.1 0.5 5.7e-12 44.4 0.2 1.8 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) RFX5_DNA_bdg PF14621.1 OAI97864.1 - 0.018 14.6 3.7 0.02 14.4 2.6 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain AT_hook PF02178.14 OAI97864.1 - 0.25 11.1 7.9 0.68 9.8 5.5 1.8 1 0 0 1 1 1 0 AT hook motif DUF4631 PF15450.1 OAI97865.1 - 0.0065 14.8 6.3 0.0083 14.4 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) GAS PF13851.1 OAI97865.1 - 0.022 13.9 7.8 0.036 13.2 5.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 OAI97865.1 - 0.4 11.0 8.9 0.87 9.9 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 OAI97865.1 - 1.2 9.2 4.9 2.1 8.4 3.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.6 OAI97865.1 - 3.5 6.7 9.4 6.1 5.9 0.2 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Oxysterol_BP PF01237.13 OAI97871.1 - 1e-81 274.1 0.0 1.3e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein XPA_C PF05181.7 OAI97872.1 - 2.1e-27 94.4 1.2 4.3e-27 93.4 0.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 OAI97872.1 - 0.05 13.2 4.9 0.052 13.2 0.6 2.3 2 0 0 2 2 2 0 XPA protein N-terminal PhnA_Zn_Ribbon PF08274.7 OAI97872.1 - 6.9 6.5 8.8 2.8 7.7 0.5 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prenyltransf PF01255.14 OAI97873.1 - 9.8e-27 93.5 0.0 1.1e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rad52_Rad22 PF04098.10 OAI97882.1 - 8.6e-12 45.0 0.3 2e-11 43.8 0.2 1.6 1 1 1 2 2 2 1 Rad52/22 family double-strand break repair protein TAXi_N PF14543.1 OAI97882.1 - 0.055 13.4 0.2 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal MFS_1 PF07690.11 OAI97883.1 - 5.2e-39 133.9 50.6 5.2e-39 133.9 35.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI97883.1 - 2.1e-11 43.0 9.3 2.1e-11 43.0 6.5 3.2 2 1 0 3 3 3 2 Sugar (and other) transporter MBOAT_2 PF13813.1 OAI97884.1 - 1.1e-12 47.8 5.7 4.8e-06 26.5 0.3 3.4 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family RVT_1 PF00078.22 OAI97885.1 - 3.1e-17 62.6 0.0 6.1e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97885.1 - 7.6e-10 38.9 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97885.1 - 0.0044 17.5 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI97885.1 - 0.044 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAI97885.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein MOSC_N PF03476.11 OAI97888.1 - 1.1e-16 60.6 0.0 2.2e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Retrotrans_gag PF03732.12 OAI97892.1 - 0.1 12.6 1.1 0.55 10.3 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVP PF00077.15 OAI97893.1 - 7.6e-05 22.5 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAI97893.1 - 0.0001 22.7 0.0 0.00034 21.0 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI97893.1 - 0.057 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease YjcZ PF13990.1 OAI97904.1 - 0.00078 18.6 0.9 0.00093 18.4 0.7 1.1 1 0 0 1 1 1 1 YjcZ-like protein NeA_P2 PF12312.3 OAI97904.1 - 0.085 12.0 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DUF601 PF04642.7 OAI97904.1 - 0.087 12.1 4.1 0.11 11.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DUF4164 PF13747.1 OAI97904.1 - 0.12 12.5 8.7 0.76 9.9 3.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Mnd1 PF03962.10 OAI97904.1 - 0.26 10.9 4.5 0.32 10.6 3.1 1.1 1 0 0 1 1 1 0 Mnd1 family Seryl_tRNA_N PF02403.17 OAI97904.1 - 0.57 10.2 10.8 0.08 12.9 2.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 OAI97904.1 - 2.2 7.6 4.3 3.8 6.9 0.0 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Ank PF00023.25 OAI97908.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 OAI97908.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Y_phosphatase2 PF03162.8 OAI97909.1 - 3.2e-22 78.6 0.0 1.4e-12 47.3 0.0 2.4 3 0 0 3 3 3 2 Tyrosine phosphatase family Ribosomal_60s PF00428.14 OAI97909.1 - 0.00017 21.9 1.5 0.00017 21.9 1.1 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein TFIIA PF03153.8 OAI97909.1 - 0.011 15.6 1.6 0.011 15.6 1.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 OAI97909.1 - 0.047 13.1 13.7 0.087 12.3 9.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 OAI97909.1 - 0.091 11.9 9.6 0.14 11.2 6.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 OAI97909.1 - 0.17 11.4 11.6 0.27 10.8 8.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleo_P87 PF07267.6 OAI97909.1 - 0.37 9.4 2.7 0.43 9.2 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.8 OAI97909.1 - 1.2 7.7 9.5 1.7 7.2 6.6 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 OAI97909.1 - 6.6 4.5 15.2 9.6 3.9 10.5 1.2 1 0 0 1 1 1 0 Nop14-like family Caerin_1 PF07440.7 OAI97910.1 - 1.6 8.6 3.9 3.6 7.5 2.7 1.5 1 0 0 1 1 1 0 Caerin 1 protein Aminotran_5 PF00266.14 OAI97915.1 - 3.3e-05 22.8 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V BPL_N PF09825.4 OAI97916.1 - 4.5e-80 269.1 0.0 6.5e-80 268.6 0.0 1.3 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 OAI97916.1 - 1.3e-13 51.0 0.0 2.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 OAI97916.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain GATase_3 PF07685.9 OAI97916.1 - 0.029 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain NTP_transf_2 PF01909.18 OAI97921.1 - 0.0053 17.0 0.0 0.0089 16.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain adh_short PF00106.20 OAI97921.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Helicase_C PF00271.26 OAI97925.1 - 0.0018 18.0 0.1 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CRISPR_Cse1 PF09481.5 OAI97926.1 - 1.4e-104 350.5 0.1 1.6e-104 350.3 0.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) KilA-N PF04383.8 OAI97927.1 - 6.6e-10 38.6 0.0 8e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain Cas_Cas5d PF09704.5 OAI97928.1 - 2.7e-43 148.1 0.2 3.7e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) Cas_CT1975 PF09344.5 OAI97929.1 - 1.1e-62 212.4 3.0 1.2e-62 212.3 2.1 1.0 1 0 0 1 1 1 1 CT1975-like protein CRISPR_Cse2 PF09485.5 OAI97930.1 - 4.2e-23 81.9 3.0 4.9e-23 81.7 2.1 1.0 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) RVT_1 PF00078.22 OAI97932.1 - 1.9e-19 69.8 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97932.1 - 0.0021 18.5 0.1 0.0061 17.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 OAI97932.1 - 0.17 12.0 0.0 0.52 10.4 0.0 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein rve PF00665.21 OAI97933.1 - 2.2e-15 56.7 0.0 4.7e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Golgin_A5 PF09787.4 OAI97939.1 - 9.9 4.5 7.3 12 4.2 5.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 RVT_1 PF00078.22 OAI97940.1 - 2.2e-17 63.1 0.0 4.2e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI97940.1 - 1.4e-12 47.7 0.0 3.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI97940.1 - 3.2e-05 24.3 0.3 0.00023 21.6 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI97940.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI97940.1 - 0.02 14.7 0.5 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF423 PF04241.10 OAI97947.1 - 0.016 15.0 0.9 0.045 13.6 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Peptidase_M1 PF01433.15 OAI97948.1 - 4e-38 131.5 0.0 4.9e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 FAD_binding_2 PF00890.19 OAI97952.1 - 1.6e-126 422.5 2.9 2.2e-126 422.1 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 OAI97952.1 - 4.2e-48 162.4 2.6 6.2e-48 161.8 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 OAI97952.1 - 1.2e-05 24.4 0.4 0.011 14.8 0.1 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 OAI97952.1 - 6.5e-05 21.9 1.0 0.038 12.8 1.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 OAI97952.1 - 8.6e-05 21.5 0.2 0.0044 15.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAI97952.1 - 0.00018 21.4 1.5 0.029 14.2 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAI97952.1 - 0.006 15.6 0.2 0.012 14.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 OAI97952.1 - 0.46 8.9 3.0 0.4 9.0 0.5 2.1 3 0 0 3 3 3 0 HI0933-like protein RVT_1 PF00078.22 OAI97955.1 - 4.9e-32 111.0 0.0 8e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI97955.1 - 6.7e-15 55.5 0.0 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAI97955.1 - 3.4e-10 39.5 0.0 7.5e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RRM_1 PF00076.17 OAI97960.1 - 1.5e-10 40.5 0.0 2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI97960.1 - 3.5e-05 23.6 0.0 4.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI97960.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCR1_C PF12550.3 OAI97965.1 - 0.0077 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MIS13 PF08202.6 OAI97965.1 - 0.035 13.1 0.2 0.053 12.5 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family RVT_1 PF00078.22 OAI97967.1 - 1.5e-05 24.5 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAI97967.1 - 0.0035 16.9 0.1 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase FHA PF00498.21 OAI97972.1 - 0.00016 21.7 0.1 0.00047 20.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain FHA PF00498.21 OAI97973.1 - 0.038 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 FHA domain DUF1942 PF09167.6 OAI97978.1 - 0.13 12.0 0.1 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) BUD22 PF09073.5 OAI97981.1 - 0.00018 20.6 9.2 0.00024 20.2 6.4 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 OAI97981.1 - 0.0054 14.7 9.4 0.007 14.3 6.5 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 OAI97981.1 - 0.06 12.6 9.6 0.077 12.2 6.6 1.2 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.8 OAI97981.1 - 0.086 12.0 2.7 0.14 11.3 1.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3375 PF11855.3 OAI97981.1 - 0.11 11.2 1.7 0.17 10.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Nop25 PF09805.4 OAI97981.1 - 0.13 12.3 5.0 0.2 11.7 3.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CDC45 PF02724.9 OAI97981.1 - 0.16 9.9 6.7 0.19 9.6 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 OAI97981.1 - 0.34 8.9 5.6 0.45 8.5 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.4 OAI97981.1 - 0.51 9.0 24.3 1.2 7.7 16.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 OAI97981.1 - 0.58 8.5 18.0 0.69 8.3 12.5 1.2 1 1 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 OAI97981.1 - 0.81 9.3 10.0 1.4 8.5 7.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.5 OAI97981.1 - 2.4 8.7 19.8 5.2 7.7 13.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DDE_Tnp_4 PF13359.1 OAI97982.1 - 8e-12 45.0 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF2362 PF10154.4 OAI97983.1 - 0.049 12.2 0.1 0.073 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) D123 PF07065.9 OAI97983.1 - 0.12 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 D123 FliX PF10768.4 OAI97983.1 - 1.7 8.8 10.2 0.29 11.3 1.3 2.2 2 0 0 2 2 2 0 Class II flagellar assembly regulator GCR1_C PF12550.3 OAI97984.1 - 2.3e-17 62.5 0.1 4.1e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PIGA PF08288.7 OAI97987.1 - 6.6e-42 141.8 0.1 1.2e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAI97987.1 - 7.7e-21 74.2 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAI97987.1 - 2.5e-17 63.1 1.0 6.6e-17 61.7 0.7 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAI97987.1 - 5.4e-14 52.6 0.3 1e-13 51.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAI97987.1 - 1.4e-08 34.9 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAI97987.1 - 4.3e-05 23.3 0.0 6.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like RVT_3 PF13456.1 OAI97988.1 - 0.007 16.1 0.3 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 OAI97989.1 - 1.1e-05 24.9 0.0 2.8e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RPEL PF02755.10 OAI97990.1 - 0.12 11.7 0.4 0.23 10.8 0.3 1.5 1 0 0 1 1 1 0 RPEL repeat zinc_ribbon_2 PF13240.1 OAI97990.1 - 0.41 10.2 7.9 0.36 10.3 0.2 3.5 3 0 0 3 3 3 0 zinc-ribbon domain RVT_1 PF00078.22 OAI97996.1 - 1.4e-19 70.2 0.0 3.2e-19 69.1 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI97996.1 - 6.3e-06 26.6 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.21 OAI97996.1 - 1.8e-05 24.8 0.0 6.4e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 OAI97996.1 - 0.0022 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI97996.1 - 0.027 14.3 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_3 PF13358.1 OAI97996.1 - 0.051 13.3 0.0 0.68 9.6 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease GCR1_C PF12550.3 OAI98001.1 - 3.1e-05 23.7 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_28 PF13518.1 OAI98001.1 - 0.34 10.9 2.5 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain WEMBL PF05701.6 OAI98005.1 - 0.0034 15.9 8.7 0.0042 15.6 6.0 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Perilipin PF03036.11 OAI98005.1 - 0.0039 16.0 3.8 0.0049 15.7 2.7 1.0 1 0 0 1 1 1 1 Perilipin family Filament PF00038.16 OAI98005.1 - 0.0054 16.2 6.2 0.0071 15.8 4.3 1.1 1 0 0 1 1 1 1 Intermediate filament protein ERM PF00769.14 OAI98005.1 - 0.076 12.5 8.4 0.11 12.0 5.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cob_adeno_trans PF01923.13 OAI98005.1 - 0.099 12.4 1.4 0.13 11.9 1.0 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Mnd1 PF03962.10 OAI98005.1 - 0.11 12.1 6.9 0.15 11.7 4.8 1.1 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 OAI98005.1 - 0.29 10.7 6.1 0.39 10.2 4.2 1.2 1 0 0 1 1 1 0 IncA protein Med4 PF10018.4 OAI98005.1 - 0.37 10.1 7.0 0.34 10.2 0.4 2.2 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF2959 PF11172.3 OAI98005.1 - 0.44 10.2 4.6 0.6 9.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) APG6 PF04111.7 OAI98005.1 - 2 7.3 7.2 2.7 6.9 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DMPK_coil PF08826.5 OAI98005.1 - 4.5 7.2 10.6 11 5.9 3.0 2.4 1 1 1 2 2 2 0 DMPK coiled coil domain like WEMBL PF05701.6 OAI98006.1 - 0.00087 17.8 10.0 0.001 17.6 6.9 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Bestrophin PF01062.16 OAI98006.1 - 0.013 14.5 1.7 0.048 12.6 0.2 1.8 1 1 1 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF342 PF03961.8 OAI98006.1 - 0.014 13.8 2.5 0.016 13.6 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CAF-1_p150 PF11600.3 OAI98006.1 - 0.014 14.7 7.5 0.016 14.5 5.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ERM PF00769.14 OAI98006.1 - 0.018 14.6 12.3 0.022 14.2 8.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 OAI98006.1 - 0.027 14.0 6.2 0.03 13.8 4.3 1.1 1 0 0 1 1 1 0 IncA protein Pinin_SDK_memA PF04696.8 OAI98006.1 - 0.03 13.9 8.3 0.045 13.3 5.8 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF1311 PF07007.7 OAI98006.1 - 0.052 13.6 6.8 0.075 13.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) EzrA PF06160.7 OAI98006.1 - 0.099 10.8 5.3 0.12 10.5 3.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA EMP24_GP25L PF01105.19 OAI98006.1 - 0.11 12.2 0.4 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Mnd1 PF03962.10 OAI98006.1 - 0.13 11.9 8.0 0.16 11.6 5.6 1.1 1 0 0 1 1 1 0 Mnd1 family Fib_alpha PF08702.5 OAI98006.1 - 0.15 12.1 0.8 0.21 11.7 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 OAI98006.1 - 0.4 8.4 3.4 0.47 8.2 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2959 PF11172.3 OAI98006.1 - 0.41 10.3 6.7 0.53 10.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) HAUS6_N PF14661.1 OAI98006.1 - 0.66 9.2 6.9 0.76 9.0 4.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 OAI98006.1 - 1.1 8.2 6.6 1.3 8.0 4.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2951 PF11166.3 OAI98006.1 - 1.1 9.1 7.0 1.7 8.5 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DUF2664 PF10867.3 OAI98006.1 - 1.5 9.5 6.3 7.1 7.3 1.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2664) Sipho_Gp157 PF05565.6 OAI98006.1 - 3.3 7.2 7.3 60 3.1 5.1 2.1 1 1 0 1 1 1 0 Siphovirus Gp157 YlqD PF11068.3 OAI98006.1 - 4.2 7.4 10.1 12 5.9 1.1 1.6 1 1 1 2 2 2 0 YlqD protein DMPK_coil PF08826.5 OAI98006.1 - 6.9 6.6 13.8 0.98 9.3 1.0 3.0 1 1 2 3 3 3 0 DMPK coiled coil domain like TPR_MLP1_2 PF07926.7 OAI98006.1 - 7.1 6.3 13.5 17 5.1 9.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein RF-1 PF00472.15 OAI98009.1 - 0.1 12.4 0.9 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 RF-1 domain DUF1729 PF08354.5 OAI98013.1 - 4.3e-30 103.2 0.2 1.3e-29 101.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Ins134_P3_kin PF05770.6 OAI98025.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase MFS_1 PF07690.11 OAI98026.1 - 1.6e-28 99.4 1.1 2.3e-28 98.9 0.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI98026.1 - 4.7e-10 38.6 2.1 6.5e-10 38.1 1.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 OAI98026.1 - 0.0016 16.9 0.6 0.0027 16.1 0.4 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein ATG22 PF11700.3 OAI98026.1 - 0.026 13.0 2.2 0.052 12.0 1.0 1.7 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 OAI98026.1 - 0.048 13.4 0.2 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family TIMELESS PF04821.9 OAI98026.1 - 0.059 12.6 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Timeless protein PIF1 PF05970.9 OAI98030.1 - 3e-25 88.9 0.0 2.6e-23 82.5 0.0 2.5 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAI98030.1 - 4.3e-09 36.2 0.0 2.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAI98030.1 - 1.8e-06 27.5 3.6 1.8e-05 24.4 0.7 2.9 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 OAI98030.1 - 7.4e-05 22.8 1.7 0.00028 20.9 0.0 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAI98030.1 - 0.00012 22.1 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAI98030.1 - 0.0048 16.3 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAI98030.1 - 0.011 15.3 0.0 0.011 15.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain T2SE PF00437.15 OAI98030.1 - 0.012 14.5 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 OAI98030.1 - 0.016 14.2 0.4 0.029 13.3 0.1 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAI98030.1 - 0.016 14.4 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 OAI98030.1 - 0.017 14.6 0.0 0.052 13.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.10 OAI98030.1 - 0.019 14.8 2.5 0.035 13.9 0.1 2.4 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NACHT PF05729.7 OAI98030.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_pol_3_Rpc31 PF11705.3 OAI98030.1 - 0.024 14.5 9.1 0.044 13.7 6.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 AAA_16 PF13191.1 OAI98030.1 - 0.037 14.0 0.1 0.037 14.0 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain Mpp10 PF04006.7 OAI98030.1 - 0.048 12.0 13.4 0.065 11.6 9.3 1.1 1 0 0 1 1 1 0 Mpp10 protein NTPase_1 PF03266.10 OAI98030.1 - 0.052 13.2 0.1 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA PF00004.24 OAI98030.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAI98030.1 - 0.1 12.9 5.6 4.1 7.6 2.1 2.2 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.9 OAI98030.1 - 0.11 10.5 6.8 0.15 10.0 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CobA_CobO_BtuR PF02572.10 OAI98030.1 - 0.13 11.8 1.8 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Nop14 PF04147.7 OAI98030.1 - 0.3 8.9 10.7 0.39 8.5 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 OAI98030.1 - 0.45 9.2 15.5 0.64 8.6 10.7 1.1 1 0 0 1 1 1 0 Paf1 RXT2_N PF08595.6 OAI98030.1 - 0.99 9.1 6.3 1.7 8.4 4.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 OAI98030.1 - 1.2 7.5 15.2 1.6 7.0 10.5 1.1 1 0 0 1 1 1 0 Daxx Family AvrE PF11725.3 OAI98030.1 - 1.3 5.9 3.2 1.7 5.5 2.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor Spore_coat_CotO PF14153.1 OAI98030.1 - 1.5 8.2 11.5 2.3 7.6 8.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO AAA_18 PF13238.1 OAI98030.1 - 1.6 9.0 5.5 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 OAI98030.1 - 1.9 7.7 6.1 0.54 9.5 0.4 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Herpes_Helicase PF02689.9 OAI98030.1 - 2 6.0 2.9 1.9 6.1 0.0 2.1 2 1 1 3 3 3 0 Helicase NOA36 PF06524.7 OAI98030.1 - 2.7 7.1 4.9 3.9 6.6 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3402 PF11882.3 OAI98030.1 - 2.8 6.9 6.6 3.8 6.4 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Pox_Ag35 PF03286.9 OAI98030.1 - 3.1 7.2 8.6 5.4 6.4 6.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF605 PF04652.11 OAI98030.1 - 7.2 5.8 13.7 9.7 5.4 9.5 1.1 1 0 0 1 1 1 0 Vta1 like BTV_NS2 PF04514.7 OAI98030.1 - 7.6 5.3 10.6 11 4.7 7.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RVT_1 PF00078.22 OAI98031.1 - 1.7e-28 99.4 0.0 3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lzipper-MIP1 PF14389.1 OAI98035.1 - 0.0066 16.5 0.4 0.011 15.8 0.3 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Rox3 PF08633.5 OAI98035.1 - 0.17 12.1 1.1 0.22 11.8 0.7 1.1 1 0 0 1 1 1 0 Rox3 mediator complex subunit Nha1_C PF08619.5 OAI98035.1 - 0.34 10.1 3.1 0.41 9.8 2.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus T2SM PF04612.7 OAI98035.1 - 0.55 10.0 6.7 0.87 9.3 4.7 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Shisa PF13908.1 OAI98035.1 - 2.8 8.0 5.3 3.6 7.7 3.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator APC_CDC26 PF10471.4 OAI98035.1 - 2.9 8.7 7.1 4.8 7.9 4.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF4463 PF14703.1 OAI98036.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) PLU-1 PF08429.6 OAI98036.1 - 0.09 11.6 0.0 0.23 10.3 0.0 1.6 1 1 0 1 1 1 0 PLU-1-like protein DUF747 PF05346.6 OAI98037.1 - 1.1e-110 369.8 0.0 2e-109 365.6 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic membrane protein family RVT_1 PF00078.22 OAI98039.1 - 8.8e-29 100.3 0.0 1.7e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BLVR PF06375.6 OAI98039.1 - 0.035 13.9 11.5 0.078 12.7 7.9 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Vfa1 PF08432.5 OAI98039.1 - 0.052 13.5 7.5 0.099 12.6 5.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP1_TM PF14812.1 OAI98039.1 - 0.11 12.8 8.3 0.3 11.4 5.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C37 PF05416.7 OAI98039.1 - 0.7 8.1 6.0 1.1 7.5 4.1 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Pox_Ag35 PF03286.9 OAI98039.1 - 1.3 8.4 14.3 2.6 7.4 9.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RVT_1 PF00078.22 OAI98045.1 - 8.6e-18 64.4 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98045.1 - 3.1e-16 59.5 0.0 8.4e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98045.1 - 5.4e-05 23.6 0.3 0.00022 21.6 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease DDE_3 PF13358.1 OAI98045.1 - 0.14 11.9 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease Ribosomal_L37e PF01907.14 OAI98045.1 - 0.36 10.6 1.3 1.1 9.1 0.9 1.7 1 0 0 1 1 1 0 Ribosomal protein L37e HA2 PF04408.18 OAI98047.1 - 1.2e-25 89.4 0.0 5.7e-25 87.3 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAI98047.1 - 3.1e-23 81.7 0.0 1e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAI98047.1 - 5.8e-13 48.5 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI98047.1 - 1.7e-08 34.1 0.1 4.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAI98047.1 - 2.9e-06 27.4 0.1 8.4e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAI98047.1 - 0.00086 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 OAI98047.1 - 0.0034 17.4 0.1 0.022 14.7 0.0 2.4 3 0 0 3 3 2 1 Sigma-54 interaction domain KaiC PF06745.8 OAI98047.1 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 KaiC SRP54 PF00448.17 OAI98047.1 - 0.0095 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 OAI98047.1 - 0.01 15.7 0.1 0.083 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 OAI98047.1 - 0.017 14.9 0.2 7.3 6.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit G-alpha PF00503.15 OAI98047.1 - 0.032 12.9 0.6 0.066 11.8 0.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 OAI98047.1 - 0.053 13.2 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 OAI98047.1 - 0.055 13.7 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 OAI98047.1 - 0.076 12.6 0.6 0.77 9.4 0.0 2.4 3 0 0 3 3 2 0 NACHT domain Sigma54_activat PF00158.21 OAI98047.1 - 0.086 12.3 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Myosin_head PF00063.16 OAI98047.1 - 0.088 10.8 0.0 0.14 10.1 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) TLP-20 PF06088.6 OAI98047.1 - 0.15 11.7 3.0 0.45 10.1 2.1 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Syntaxin PF00804.20 OAI98048.1 - 4e-12 46.1 2.7 4e-12 46.1 1.9 2.8 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 OAI98048.1 - 4.1e-07 29.5 15.1 1.6e-06 27.7 5.2 3.6 3 0 0 3 3 3 1 SNARE domain DUF4298 PF14131.1 OAI98048.1 - 0.13 12.1 5.1 2.3 8.1 0.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF1345 PF07077.6 OAI98048.1 - 0.14 11.6 0.2 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Shisa PF13908.1 OAI98048.1 - 0.15 12.2 0.1 0.15 12.2 0.1 3.6 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Toxin_52 PF15605.1 OAI98048.1 - 0.15 11.9 2.9 13 5.7 0.1 3.1 2 1 0 2 2 2 0 Putative toxin 52 Herpes_US9 PF06072.6 OAI98048.1 - 0.31 10.8 2.9 0.66 9.8 2.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 TPR_14 PF13428.1 OAI98048.1 - 7.3 7.5 7.2 3.1 8.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Rhamno_transf PF11316.3 OAI98051.1 - 0.072 12.2 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase RVT_1 PF00078.22 OAI98054.1 - 0.00088 18.6 0.0 0.0034 16.7 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MHYT PF03707.11 OAI98055.1 - 0.36 10.9 7.2 0.76 9.9 5.0 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DEAD PF00270.24 OAI98063.1 - 1.7e-11 43.8 0.0 3.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI98063.1 - 2e-08 33.9 0.0 6.1e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C2H2 PF00096.21 OAI98063.1 - 0.11 12.9 12.8 0.074 13.4 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI98063.1 - 5.8 7.4 14.9 1.5 9.3 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Malate_synthase PF01274.17 OAI98066.1 - 0.0036 15.3 0.0 0.0047 15.0 0.0 1.2 1 0 0 1 1 1 1 Malate synthase ALS2CR8 PF15299.1 OAI98066.1 - 0.081 12.5 1.1 0.13 11.7 0.0 1.9 2 1 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Malate_synthase PF01274.17 OAI98067.1 - 0.083 10.8 0.0 0.083 10.8 0.0 1.2 1 0 0 1 1 1 0 Malate synthase DUF1501 PF07394.7 OAI98070.1 - 0.001 17.9 1.4 0.001 17.9 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1501) SAM_decarbox PF01536.11 OAI98071.1 - 1.6e-80 270.2 0.0 2.4e-56 190.8 0.0 2.7 2 2 0 2 2 2 2 Adenosylmethionine decarboxylase ATE_N PF04376.8 OAI98071.1 - 0.013 15.2 0.0 0.042 13.6 0.0 1.9 1 1 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus Mito_fiss_reg PF05308.6 OAI98072.1 - 0.15 11.4 3.4 0.21 10.8 2.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator P30 PF07390.6 OAI98073.1 - 2 7.8 6.4 1 8.8 2.9 1.6 1 1 0 1 1 1 0 Mycoplasma P30 protein LIP PF03583.9 OAI98074.1 - 7.7e-62 209.1 0.1 1e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase DUF829 PF05705.9 OAI98074.1 - 0.075 12.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) rve PF00665.21 OAI98076.1 - 2.3e-12 47.1 0.0 9e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAI98076.1 - 6.8e-08 32.1 0.0 1.8e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 OAI98076.1 - 1.8e-05 24.2 0.0 4.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 OAI98076.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_3 PF13456.1 OAI98076.1 - 0.072 12.8 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like PerC PF06069.6 OAI98076.1 - 0.57 10.2 3.5 1.8 8.6 0.4 2.6 2 0 0 2 2 2 0 PerC transcriptional activator BRF1 PF07741.8 OAI98076.1 - 2.2 8.5 7.9 0.19 11.9 0.8 2.5 3 0 0 3 3 3 0 Brf1-like TBP-binding domain NmrA PF05368.8 OAI98077.1 - 4.7e-21 75.1 0.0 5.9e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAI98077.1 - 1.2e-10 41.7 0.1 4e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 OAI98077.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF2613 PF11021.3 OAI98077.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) DUF1079 PF06435.6 OAI98077.1 - 0.087 12.7 0.2 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) PS_Dcarbxylase PF02666.10 OAI98080.1 - 2.2e-75 252.3 0.0 7.8e-74 247.3 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.6 OAI98080.1 - 0.0014 18.1 0.0 0.0036 16.8 0.0 1.6 1 0 0 1 1 1 1 MNLL subunit AA_permease PF00324.16 OAI98081.1 - 5.2e-137 457.0 45.6 6.4e-137 456.7 31.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAI98081.1 - 1.2e-39 136.0 48.5 1.5e-39 135.7 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease Repressor_Mnt PF11423.3 OAI98081.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Regulatory protein Mnt DnaJ PF00226.26 OAI98082.1 - 2.2e-22 78.5 0.7 3.9e-22 77.7 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAI98082.1 - 2e-20 72.4 0.0 8.6e-19 67.2 0.0 2.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAI98082.1 - 1.7e-14 53.6 20.5 2.8e-14 52.9 14.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 OAI98082.1 - 0.017 14.8 12.7 0.51 10.0 0.6 2.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family RVT_1 PF00078.22 OAI98085.1 - 5.2e-17 61.9 0.0 9.6e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98085.1 - 3.5e-14 52.9 0.0 9.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98085.1 - 9.1e-05 22.8 0.4 0.00031 21.1 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98085.1 - 0.026 14.4 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAI98086.1 - 0.0086 16.1 0.1 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 OAI98087.1 - 0.0048 17.3 0.1 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98087.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Not3 PF04065.10 OAI98089.1 - 1.7e-95 318.7 20.5 1.7e-95 318.7 14.2 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 OAI98089.1 - 1.7e-46 157.4 11.1 6.3e-46 155.5 7.7 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 OAI98089.1 - 0.0017 17.8 2.1 0.0039 16.6 1.5 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Ribosomal_L19 PF01245.15 OAI98091.1 - 2.6e-22 78.7 0.2 4.2e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 BROMI PF14961.1 OAI98091.1 - 0.16 9.0 0.0 0.19 8.8 0.0 1.0 1 0 0 1 1 1 0 Broad-minded protein Nop14 PF04147.7 OAI98096.1 - 4.6e-71 239.9 0.0 5.2e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Nop14-like family DEAD PF00270.24 OAI98098.1 - 7.5e-16 58.0 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI98098.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 OAI98098.1 - 0.25 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Nop14 PF04147.7 OAI98099.1 - 5.4e-114 381.9 47.3 5.4e-114 381.9 32.8 1.3 1 1 0 1 1 1 1 Nop14-like family KilA-N PF04383.8 OAI98104.1 - 0.00023 20.7 0.1 0.00074 19.1 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain Dimer_Tnp_hAT PF05699.9 OAI98105.1 - 1.4e-25 88.7 0.2 1.4e-25 88.7 0.1 2.2 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAI98105.1 - 1.8e-08 33.9 4.0 3.4e-08 33.1 2.8 1.5 1 0 0 1 1 1 1 BED zinc finger DUF2357 PF09823.4 OAI98105.1 - 0.0089 15.1 0.1 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) Pex19 PF04614.7 OAI98110.1 - 0.066 12.8 2.2 0.12 11.9 1.5 1.4 1 0 0 1 1 1 0 Pex19 protein family zf-CCHC_4 PF14392.1 OAI98110.1 - 1.8 8.2 7.1 1.3 8.7 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 OAI98111.1 - 5.5e-32 110.8 0.0 9e-32 110.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI98111.1 - 1.1e-13 51.7 0.0 2.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAI98111.1 - 1.4e-10 40.7 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4400 PF14348.1 OAI98111.1 - 0.085 12.2 0.7 0.2 11.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) UBN2 PF14223.1 OAI98112.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Het-C PF07217.6 OAI98117.1 - 1.2e-161 538.9 0.0 1.8e-161 538.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF2780 PF11075.3 OAI98117.1 - 0.0045 17.0 1.1 0.023 14.7 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function VcgC/VcgE (DUF2780) DUF1572 PF07609.6 OAI98117.1 - 0.08 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) WD40 PF00400.27 OAI98133.1 - 2.2e-10 39.9 0.2 2.5e-06 27.1 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat VID27 PF08553.5 OAI98135.1 - 7.6e-232 771.9 6.3 1.1e-158 529.9 1.1 2.1 1 1 1 2 2 2 2 VID27 cytoplasmic protein Rad60-SLD PF11976.3 OAI98138.1 - 1.3e-05 24.8 0.2 0.021 14.5 0.0 3.3 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like rve PF00665.21 OAI98139.1 - 1.3e-14 54.3 0.0 6.9e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98139.1 - 2.7e-05 24.5 0.0 9.4e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98139.1 - 3.2e-05 23.6 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98139.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAI98139.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.5 OAI98139.1 - 0.22 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease DDE_Tnp_4 PF13359.1 OAI98144.1 - 2.3e-34 118.3 0.0 4e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI98144.1 - 5e-07 29.3 0.0 3.4e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI98144.1 - 7.3e-06 25.6 0.1 0.00011 21.8 0.1 2.2 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 OAI98144.1 - 9.6e-05 21.8 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 OAI98144.1 - 0.048 13.3 0.1 0.048 13.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Brr6_like_C_C PF10104.4 OAI98148.1 - 0.16 11.4 0.9 0.61 9.6 0.1 2.2 2 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain zf-C2H2_4 PF13894.1 OAI98148.1 - 0.22 11.9 2.1 0.63 10.5 1.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger IL15 PF02372.10 OAI98154.1 - 0.0039 16.9 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Interleukin 15 PMD PF10536.4 OAI98154.1 - 0.037 13.0 0.0 0.037 13.0 0.0 1.0 1 0 0 1 1 1 0 Plant mobile domain AAA_19 PF13245.1 OAI98155.1 - 2.1e-09 37.0 0.1 4e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAI98155.1 - 3.8e-08 33.1 0.1 5.2e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 OAI98155.1 - 4.1e-08 32.5 0.0 5.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase T2SE PF00437.15 OAI98155.1 - 5.9e-05 22.1 0.0 7.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 OAI98155.1 - 9.2e-05 21.8 0.2 0.00014 21.2 0.1 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 OAI98155.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAI98155.1 - 0.00091 19.2 0.0 0.0021 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 OAI98155.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 OAI98155.1 - 0.0018 18.4 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 OAI98155.1 - 0.0034 16.6 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.7 OAI98155.1 - 0.0046 16.6 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_32 PF13654.1 OAI98155.1 - 0.0058 15.3 0.0 0.0081 14.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAI98155.1 - 0.0062 15.5 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 OAI98155.1 - 0.0064 16.0 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAI98155.1 - 0.0099 15.7 0.0 0.052 13.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAI98155.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 OAI98155.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 OAI98155.1 - 0.019 13.6 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 OAI98155.1 - 0.019 15.7 0.0 0.032 15.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAI98155.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 OAI98155.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 OAI98155.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAI98155.1 - 0.034 14.4 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 OAI98155.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 OAI98155.1 - 0.066 13.7 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein ATP_bind_1 PF03029.12 OAI98155.1 - 0.074 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 OAI98155.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 IstB_IS21 PF01695.12 OAI98155.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 OAI98155.1 - 0.083 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 OAI98155.1 - 0.093 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAI98155.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase RNA12 PF10443.4 OAI98155.1 - 0.1 11.0 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DEAD PF00270.24 OAI98155.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Sigma54_activat PF00158.21 OAI98155.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.7 OAI98155.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein DEAD PF00270.24 OAI98161.1 - 2.6e-11 43.2 0.0 4.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 OAI98161.1 - 0.0029 17.8 9.7 0.11 12.8 3.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type AAA_10 PF12846.2 OAI98161.1 - 0.0055 16.1 0.3 2.3 7.5 0.0 3.0 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 OAI98161.1 - 0.18 11.6 0.2 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 DcuC PF03606.10 OAI98161.1 - 0.27 9.4 0.0 0.44 8.7 0.0 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier zf-C2H2_4 PF13894.1 OAI98161.1 - 3.3 8.2 10.1 4.9 7.7 1.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 OAI98164.1 - 2.4e-60 203.8 0.0 4e-59 199.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.3 OAI98164.1 - 1.6e-41 142.1 0.0 9.7e-38 129.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 OAI98164.1 - 5.6e-41 140.3 0.0 6.7e-40 136.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI98164.1 - 8.8e-05 21.5 0.0 0.03 13.2 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 OAI98164.1 - 0.057 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHAT PF12770.2 OAI98165.1 - 0.0022 17.1 0.1 0.0024 17.0 0.1 1.0 1 0 0 1 1 1 1 CHAT domain ODC_AZ PF02100.12 OAI98166.1 - 7.4e-16 57.6 0.0 1.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF218 PF02698.12 OAI98168.1 - 0.0097 15.4 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 DUF218 domain DUF1845 PF08900.6 OAI98170.1 - 0.022 14.0 0.3 0.037 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Retrotrans_gag PF03732.12 OAI98170.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 OAI98173.1 - 1.6e-17 63.6 0.0 2.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98173.1 - 3.2e-17 62.7 0.0 6.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98173.1 - 2.3e-05 24.8 0.0 0.00014 22.2 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98173.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98173.1 - 0.058 13.2 0.1 0.24 11.2 0.0 2.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SlyX PF04102.7 OAI98177.1 - 0.015 15.6 1.0 0.021 15.1 0.1 1.7 2 0 0 2 2 2 0 SlyX TMF_TATA_bd PF12325.3 OAI98177.1 - 0.057 13.1 0.1 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 OAI98177.1 - 0.089 12.5 0.8 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pil1 PF13805.1 OAI98180.1 - 0.033 13.3 0.5 0.036 13.2 0.4 1.0 1 0 0 1 1 1 0 Eisosome component PIL1 DUF2997 PF11211.3 OAI98185.1 - 0.32 10.4 2.0 0.68 9.3 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) FHA PF00498.21 OAI98189.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 FHA domain Exo5 PF09810.4 OAI98193.1 - 8.6e-50 169.7 0.3 1.1e-43 149.6 0.2 3.3 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease AAA_33 PF13671.1 OAI98194.1 - 1.1e-19 70.7 0.9 6.2e-19 68.2 0.6 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAI98194.1 - 9.8e-10 37.8 0.0 2e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin tRNA_lig_kinase PF08303.6 OAI98194.1 - 3.8e-07 30.1 0.1 5.8e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.5 OAI98194.1 - 1.3e-06 27.8 1.3 0.00041 19.6 1.0 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 OAI98194.1 - 0.00023 21.4 1.5 0.0091 16.3 1.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAI98194.1 - 0.00029 20.9 0.0 0.0007 19.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 OAI98194.1 - 0.0016 18.1 0.2 0.11 12.1 0.0 2.3 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 OAI98194.1 - 0.02 15.6 0.0 0.033 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 OAI98194.1 - 0.055 13.1 0.1 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 OAI98194.1 - 0.1 11.9 0.1 5.4 6.3 0.1 2.7 2 1 0 2 2 2 0 Thymidylate kinase G-alpha PF00503.15 OAI98194.1 - 0.18 10.4 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit SKI PF01202.17 OAI98194.1 - 0.19 11.6 0.2 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Lamp PF01299.12 OAI98195.1 - 0.052 12.7 6.9 0.061 12.4 4.8 1.1 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF605 PF04652.11 OAI98195.1 - 0.98 8.7 3.6 1.3 8.3 2.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF1517 PF07466.6 OAI98195.1 - 2 7.3 13.1 0.94 8.4 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) ERCC4 PF02732.10 OAI98196.1 - 8.8e-26 90.3 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 OAI98196.1 - 0.00031 20.8 0.0 0.0007 19.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain Helicase_C PF00271.26 OAI98199.1 - 5.6e-11 42.1 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI98199.1 - 7.1e-05 22.3 0.0 0.00023 20.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 OAI98199.1 - 0.025 14.9 8.4 0.38 11.1 1.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAI98199.1 - 0.79 10.2 10.2 3.7 8.1 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RVT_1 PF00078.22 OAI98202.1 - 8.8e-19 67.7 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98202.1 - 4.5e-15 55.8 0.0 9.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98202.1 - 0.0054 17.2 0.3 0.024 15.1 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF454 PF04304.8 OAI98202.1 - 0.038 14.0 2.2 0.04 13.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Peptidase_C48 PF02902.14 OAI98207.1 - 2.5e-13 50.1 0.0 7.9e-13 48.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cyclin_N PF00134.18 OAI98208.1 - 0.007 15.9 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain IBR PF01485.16 OAI98209.1 - 0.66 9.8 4.8 1.6 8.6 3.4 1.6 1 0 0 1 1 1 0 IBR domain PTPA PF03095.10 OAI98212.1 - 0.00015 21.0 0.1 0.00034 19.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein Anticodon_1 PF08264.8 OAI98213.1 - 1.2e-11 44.6 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.17 OAI98213.1 - 4e-11 41.6 0.0 6.8e-11 40.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAI98213.1 - 8.6e-10 37.8 0.0 1.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 OAI98213.1 - 2.3e-07 30.2 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.17 OAI98215.1 - 8.8e-07 27.3 0.0 4.8e-06 24.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Ycf1 PF05758.7 OAI98218.1 - 0.00053 17.8 0.9 0.00053 17.8 0.6 1.0 1 0 0 1 1 1 1 Ycf1 BAF1_ABF1 PF04684.8 OAI98218.1 - 0.0015 17.5 21.5 0.0019 17.1 14.9 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 OAI98218.1 - 0.0024 16.1 15.8 0.0024 16.1 10.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BRF1 PF07741.8 OAI98218.1 - 0.018 15.2 3.6 0.024 14.8 2.5 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spt20 PF12090.3 OAI98218.1 - 0.018 14.3 2.9 0.024 13.9 2.0 1.2 1 0 0 1 1 1 0 Spt20 family Dehydrin PF00257.14 OAI98218.1 - 0.037 14.3 10.2 0.052 13.8 7.1 1.2 1 0 0 1 1 1 0 Dehydrin FAM60A PF15396.1 OAI98218.1 - 0.055 13.2 2.5 0.061 13.0 1.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A MSP PF01716.13 OAI98218.1 - 0.058 12.4 1.8 0.19 10.7 1.3 1.7 1 1 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide DUF4045 PF13254.1 OAI98218.1 - 0.063 12.5 5.5 0.075 12.3 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2201_N PF13203.1 OAI98218.1 - 0.064 12.4 7.3 0.077 12.1 5.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain AP-5_subunit_s1 PF15001.1 OAI98218.1 - 0.066 13.1 5.5 0.13 12.1 3.8 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Pex16 PF08610.5 OAI98218.1 - 0.12 11.3 3.2 0.14 11.1 2.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FLO_LFY PF01698.11 OAI98218.1 - 0.14 10.9 6.4 0.21 10.4 4.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_C58 PF03543.9 OAI98218.1 - 0.14 11.6 9.4 0.18 11.2 6.5 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF4175 PF13779.1 OAI98218.1 - 0.14 9.8 19.9 0.17 9.5 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 OAI98218.1 - 0.15 11.7 7.3 0.2 11.3 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 OAI98218.1 - 0.2 10.9 3.9 0.23 10.7 2.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FimP PF09766.4 OAI98218.1 - 0.23 10.4 13.8 0.3 10.1 9.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Chordopox_A13L PF05961.6 OAI98218.1 - 0.28 11.1 3.5 0.53 10.2 2.4 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4407 PF14362.1 OAI98218.1 - 0.44 9.4 10.1 0.57 9.0 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G0-G1_switch_2 PF15103.1 OAI98218.1 - 0.72 10.1 5.1 1.3 9.3 3.5 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Hid1 PF12722.2 OAI98218.1 - 0.81 7.2 5.7 0.87 7.1 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 OAI98218.1 - 0.82 8.0 3.2 0.93 7.8 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3464 PF11947.3 OAI98218.1 - 0.87 9.0 3.0 1.1 8.6 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) UPF0560 PF10577.4 OAI98218.1 - 1.5 6.9 10.0 2 6.6 6.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SHR3_chaperone PF08229.6 OAI98218.1 - 2.4 7.0 7.9 4.2 6.2 5.4 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Serinc PF03348.10 OAI98218.1 - 2.5 6.7 7.0 3.2 6.3 4.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.14 OAI98218.1 - 3.2 6.3 9.4 3.8 6.1 6.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein E_Pc_C PF06752.7 OAI98218.1 - 3.5 7.0 18.1 4.3 6.7 12.6 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF912 PF06024.7 OAI98218.1 - 3.6 7.6 7.1 6.5 6.8 4.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Dicty_REP PF05086.7 OAI98218.1 - 4.1 5.0 6.6 4.6 4.8 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4557 PF15101.1 OAI98218.1 - 4.3 7.1 13.3 6.4 6.5 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 OAI98218.1 - 6.5 6.5 10.5 0.6 9.8 4.3 1.4 2 0 0 2 2 1 0 Peptidase family S49 N-terminal ERF PF04404.7 OAI98218.1 - 6.5 6.2 17.2 12 5.3 11.9 1.4 1 0 0 1 1 1 0 ERF superfamily Pex19 PF04614.7 OAI98221.1 - 0.068 12.7 2.5 0.17 11.4 1.7 1.6 1 0 0 1 1 1 0 Pex19 protein family zf-CCHC_4 PF14392.1 OAI98221.1 - 0.52 10.0 7.1 1.3 8.7 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF2420 PF10336.4 OAI98222.1 - 2.5e-09 36.7 0.0 4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) RCC1 PF00415.13 OAI98223.1 - 1.6e-14 53.8 5.8 0.0089 16.2 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 OAI98223.1 - 2.7e-10 40.1 0.7 8.8e-08 32.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) BTB PF00651.26 OAI98223.1 - 2.7e-09 36.9 0.0 0.00031 20.7 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 OAI98223.1 - 1.2e-07 32.0 0.2 0.00082 19.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAI98223.1 - 1e-05 25.7 0.2 5.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAI98223.1 - 4.2e-05 23.3 3.0 0.16 12.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat RCC1_2 PF13540.1 OAI98223.1 - 0.00043 19.8 13.8 0.0022 17.5 0.0 5.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 OAI98223.1 - 0.0017 18.0 1.1 0.016 15.0 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeat ANAPC15 PF15243.1 OAI98227.1 - 0.23 11.5 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 CENP-F_leu_zip PF10473.4 OAI98227.1 - 0.7 9.7 6.6 0.054 13.3 0.8 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF605 PF04652.11 OAI98228.1 - 0.23 10.8 12.8 0.25 10.7 8.9 1.2 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 OAI98228.1 - 4.5 5.4 10.1 4.8 5.3 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein RNA_pol_Rpc4 PF05132.9 OAI98229.1 - 0.12 12.3 0.1 0.37 10.7 0.1 1.9 1 1 0 1 1 1 0 RNA polymerase III RPC4 Ribosomal_60s PF00428.14 OAI98229.1 - 2.2 8.7 19.2 0.8 10.1 10.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Retrotrans_gag PF03732.12 OAI98236.1 - 0.0025 17.8 0.1 0.0078 16.2 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein GCR1_C PF12550.3 OAI98237.1 - 1.5e-09 37.5 0.1 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes RVT_1 PF00078.22 OAI98238.1 - 7.7e-18 64.6 0.0 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98238.1 - 5.1e-16 58.8 0.0 1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98238.1 - 0.0007 20.0 0.1 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98238.1 - 0.055 13.3 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98238.1 - 0.13 12.0 1.4 0.55 10.1 0.1 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Tyrosinase PF00264.15 OAI98240.1 - 5e-38 131.4 0.7 7.1e-38 130.9 0.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 OAI98241.1 - 8.4e-29 101.3 0.1 1.3e-28 100.7 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PCI PF01399.22 OAI98242.1 - 0.055 13.7 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 PCI domain Dimer_Tnp_hAT PF05699.9 OAI98246.1 - 2.1e-10 40.0 0.0 4.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Zn_Tnp_IS1 PF03811.8 OAI98247.1 - 0.12 11.9 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 InsA N-terminal domain FHA PF00498.21 OAI98251.1 - 1.1e-06 28.6 0.3 2.4e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 FHA domain DEAD PF00270.24 OAI98253.1 - 1.1e-41 142.0 1.9 3.3e-41 140.5 0.5 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI98253.1 - 9.1e-27 92.7 0.2 4.7e-26 90.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 OAI98253.1 - 0.00058 19.5 0.5 0.0012 18.5 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 OAI98253.1 - 0.00061 19.6 0.1 0.0012 18.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAI98253.1 - 0.0038 17.3 0.0 0.0089 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.20 OAI98253.1 - 0.042 12.9 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CMS1 PF14617.1 OAI98253.1 - 0.054 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 OAI98253.1 - 0.057 12.7 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 OAI98253.1 - 0.084 12.4 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 OAI98253.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Not1 PF04054.10 OAI98254.1 - 2e-110 369.2 0.0 5.4e-110 367.8 0.0 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 OAI98254.1 - 4.1e-55 185.4 3.5 9.6e-55 184.3 2.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) TPM PF04536.9 OAI98254.1 - 0.055 13.3 0.2 0.94 9.3 0.0 2.7 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase TPR_19 PF14559.1 OAI98258.1 - 0.0066 16.7 0.7 1.8 8.9 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat Neisseria_TspB PF05616.8 OAI98259.1 - 1.2 7.4 3.5 1.4 7.2 2.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein rve PF00665.21 OAI98262.1 - 6.3e-13 48.8 0.0 9.5e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 OAI98262.1 - 0.0005 19.6 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 OAI98262.1 - 0.0043 17.0 0.1 0.014 15.4 0.1 1.9 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAI98262.1 - 0.01 15.7 1.4 0.021 14.7 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAI98262.1 - 0.017 14.9 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAI98262.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_3 PF13456.1 OAI98262.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like RRM_6 PF14259.1 OAI98265.1 - 5.6e-12 45.4 0.0 9.3e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAI98265.1 - 2e-11 43.3 0.0 3.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI98265.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb1_5 PF04998.12 OAI98266.1 - 7.4e-88 294.3 0.5 1.7e-87 293.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAI98266.1 - 2.3e-60 203.2 0.0 5e-60 202.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAI98266.1 - 3.9e-35 120.9 0.0 8.2e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 OAI98266.1 - 6.3e-29 101.2 1.1 2.1e-23 83.1 0.0 4.2 5 0 0 5 5 5 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 OAI98266.1 - 1.5e-21 76.1 2.2 1.8e-21 75.8 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Daxx PF03344.10 OAI98266.1 - 5.6 5.3 23.5 0.93 7.8 10.7 2.1 2 0 0 2 2 2 0 Daxx Family Rad60-SLD PF11976.3 OAI98270.1 - 1.8e-05 24.3 0.0 0.11 12.1 0.0 3.8 2 1 1 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAI98270.1 - 0.089 12.1 0.1 28 4.1 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin family rve PF00665.21 OAI98271.1 - 2.6e-14 53.3 0.0 5.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 OAI98271.1 - 9.6e-07 28.5 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAI98271.1 - 1.3e-05 25.5 0.0 4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98271.1 - 2.9e-05 23.8 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI98271.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 OAI98271.1 - 0.002 17.9 1.7 0.0054 16.6 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.1 OAI98271.1 - 0.02 14.3 0.0 0.061 12.8 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Peptidase_A2E PF12382.3 OAI98271.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon peptidase DUF4310 PF14187.1 OAI98271.1 - 0.32 10.4 0.1 0.57 9.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Cpn10 PF00166.16 OAI98274.1 - 8.4e-25 86.5 0.0 9.6e-25 86.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit RRM_1 PF00076.17 OAI98275.1 - 6.4e-10 38.5 0.0 1.6e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI98275.1 - 6.8e-10 38.6 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI98275.1 - 3.3e-06 26.9 0.0 6e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Microtub_assoc PF07989.6 OAI98275.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Microtubule associated zf-AN1 PF01428.11 OAI98276.1 - 8.2e-17 60.7 35.0 6.6e-09 35.4 8.4 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger DEAD PF00270.24 OAI98277.1 - 1.2e-42 145.2 0.0 2.2e-42 144.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI98277.1 - 5.9e-21 74.1 0.0 1.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAI98277.1 - 1.3e-19 69.4 0.1 2.7e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Tombus_movement PF05318.7 OAI98277.1 - 0.47 11.1 5.5 0.73 10.4 2.5 2.5 2 0 0 2 2 2 0 Tombusvirus movement protein DZR PF12773.2 OAI98281.1 - 0.022 14.5 0.7 0.046 13.5 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Helicase_C PF00271.26 OAI98282.1 - 3.4e-11 42.8 0.0 7.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI98282.1 - 4.7e-11 42.4 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3505 PF12013.3 OAI98282.1 - 1.8e-07 31.3 0.3 9.5e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Helicase_C_4 PF13871.1 OAI98282.1 - 0.086 12.2 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Helicase_C-like DUF4413 PF14372.1 OAI98286.1 - 0.00024 21.0 0.1 0.00089 19.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) rve PF00665.21 OAI98287.1 - 1.1e-19 70.6 0.0 2.4e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98287.1 - 2.4e-16 59.7 0.0 4.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI98287.1 - 0.00011 22.5 0.0 0.00044 20.7 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98287.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Oxygenase-NA PF09859.4 OAI98287.1 - 0.027 13.8 0.1 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Retrotrans_gag PF03732.12 OAI98288.1 - 0.00012 22.0 0.0 0.00028 20.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein PilJ PF13675.1 OAI98288.1 - 0.024 14.9 1.3 7.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2205 PF10224.4 OAI98288.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Histone PF00125.19 OAI98289.1 - 7.9e-29 99.5 0.8 1.3e-28 98.8 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI98289.1 - 4e-05 23.7 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI98289.1 - 0.0052 16.8 0.1 0.038 14.0 0.1 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone T2SE PF00437.15 OAI98289.1 - 0.054 12.3 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Bromo_TP PF07524.8 OAI98289.1 - 0.11 12.1 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Asp_protease_2 PF13650.1 OAI98293.1 - 3.5e-07 30.6 0.0 8.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAI98293.1 - 7.7e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAI98293.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98293.1 - 0.0042 16.9 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAI98293.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Peptidase_A2E PF12382.3 OAI98293.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase DUF1499 PF07386.6 OAI98294.1 - 0.0096 16.0 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) Elf1 PF05129.8 OAI98294.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cys_rich_CPXG PF14255.1 OAI98294.1 - 0.15 11.9 0.2 0.77 9.6 0.0 2.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG Saccharop_dh PF03435.13 OAI98296.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Rad60-SLD PF11976.3 OAI98297.1 - 9.6e-09 34.8 0.9 3.8e-05 23.2 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like rve PF00665.21 OAI98298.1 - 5.2e-16 58.8 0.0 1.2e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain JmjC PF02373.17 OAI98301.1 - 7.6e-14 51.9 0.0 2.4e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase FYVE PF01363.16 OAI98301.1 - 7.3 6.5 10.2 0.36 10.7 2.9 1.9 2 0 0 2 2 2 0 FYVE zinc finger DUF605 PF04652.11 OAI98303.1 - 3.2 7.0 16.9 4.1 6.7 11.7 1.2 1 0 0 1 1 1 0 Vta1 like ABC_tran PF00005.22 OAI98304.1 - 1.3e-07 32.0 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter UBN2_3 PF14244.1 OAI98304.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ANP PF00212.13 OAI98304.1 - 0.0053 16.8 1.6 0.019 15.0 1.1 2.0 1 0 0 1 1 1 1 Atrial natriuretic peptide RRP7 PF12923.2 OAI98304.1 - 0.025 14.6 0.8 0.061 13.3 0.6 1.6 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Exo_endo_phos_2 PF14529.1 OAI98304.1 - 0.041 13.4 0.0 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF4219 PF13961.1 OAI98304.1 - 0.078 12.4 0.8 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Pilus_CpaD PF09476.5 OAI98308.1 - 0.034 13.6 1.3 0.045 13.2 0.9 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) ACT PF01842.20 OAI98308.1 - 0.15 11.5 0.2 0.3 10.6 0.2 1.4 1 0 0 1 1 1 0 ACT domain PDEase_I_N PF08499.7 OAI98312.1 - 0.41 10.5 2.1 0.54 10.1 0.7 1.8 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal HEAT PF02985.17 OAI98317.1 - 2.4e-24 83.1 38.4 0.053 13.6 0.0 20.4 25 0 0 25 25 25 8 HEAT repeat HEAT_2 PF13646.1 OAI98317.1 - 5.7e-23 81.0 68.8 1.4e-07 31.7 0.0 17.1 11 5 6 17 17 17 6 HEAT repeats HEAT_EZ PF13513.1 OAI98317.1 - 1e-16 60.8 70.4 0.00028 21.2 0.0 21.1 17 3 4 23 23 23 9 HEAT-like repeat CLASP_N PF12348.3 OAI98317.1 - 4.3e-14 52.4 0.1 1.7e-07 30.8 0.0 5.5 5 0 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 OAI98317.1 - 2.7e-10 40.4 0.0 0.012 16.0 0.0 7.0 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 OAI98317.1 - 0.00041 20.2 6.9 0.15 12.0 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Ecm29 PF13001.2 OAI98317.1 - 0.0018 16.8 1.3 0.079 11.4 0.0 3.8 3 1 1 4 4 4 1 Proteasome stabiliser Cnd3 PF12719.2 OAI98317.1 - 0.011 14.6 2.0 18 4.1 0.0 4.4 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain ParcG PF10274.4 OAI98317.1 - 0.012 15.5 0.5 21 4.9 0.0 4.9 4 2 1 5 5 5 0 Parkin co-regulated protein UCH PF00443.24 OAI98319.1 - 1.1e-38 132.9 0.0 1.5e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAI98319.1 - 6.9e-13 48.6 0.0 2.6e-12 46.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 OAI98321.1 - 2.8e-51 173.1 0.3 3.2e-51 172.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI98321.1 - 4.4e-18 65.9 0.0 5.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAI98321.1 - 7.7e-16 57.8 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAI98321.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAI98321.1 - 0.0002 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAI98321.1 - 0.0015 18.0 0.3 0.011 15.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAI98321.1 - 0.0015 17.7 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3902 PF13042.1 OAI98321.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) PIF1 PF05970.9 OAI98324.1 - 2e-12 46.7 0.0 7.5e-11 41.5 0.0 2.4 2 1 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.1 OAI98324.1 - 0.00027 21.0 0.0 0.00098 19.2 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 OAI98324.1 - 0.074 10.7 0.0 0.1 10.3 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.1 OAI98324.1 - 0.084 12.4 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Herpes_DNAp_acc PF04929.7 OAI98329.1 - 0.094 11.6 1.9 0.36 9.7 1.5 1.8 2 0 0 2 2 2 0 Herpes DNA replication accessory factor SRP-alpha_N PF04086.8 OAI98329.1 - 1.2 8.4 5.2 1.9 7.7 3.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal F-box PF00646.28 OAI98330.1 - 5e-07 29.2 0.3 1.1e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAI98330.1 - 0.0054 16.4 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3703 PF12487.3 OAI98330.1 - 0.0085 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3703) DUF2992 PF11208.3 OAI98331.1 - 0.083 12.7 8.9 0.14 12.0 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2360 PF10152.4 OAI98331.1 - 0.099 12.9 1.1 0.13 12.5 0.8 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Senescence_reg PF04520.8 OAI98331.1 - 0.13 12.7 6.1 0.63 10.5 3.3 2.0 2 0 0 2 2 2 0 Senescence regulator Zip PF02535.17 OAI98331.1 - 1.9 7.4 6.1 2.3 7.1 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 OAI98332.1 - 3.2 7.5 7.1 4.2 7.1 5.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit polyprenyl_synt PF00348.12 OAI98336.1 - 6.2e-40 136.6 0.0 2.1e-19 69.3 0.0 4.1 4 0 0 4 4 4 4 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 OAI98336.1 - 0.082 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 MazG-like PF12643.2 OAI98336.1 - 0.18 11.7 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 MazG-like family HEAT_PBS PF03130.11 OAI98336.1 - 0.39 11.3 3.6 29 5.5 0.1 3.2 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat PAXNEB PF05625.6 OAI98337.1 - 7.1e-31 107.3 0.0 1.6e-27 96.2 0.0 3.1 2 1 0 2 2 2 2 PAXNEB protein Brix PF04427.13 OAI98338.1 - 1.7e-38 132.2 0.0 2.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain Clat_adaptor_s PF01217.15 OAI98340.1 - 3.7e-55 185.5 0.2 4.4e-55 185.3 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_1g PF09334.6 OAI98341.1 - 2.6e-147 490.5 0.0 3.2e-147 490.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAI98341.1 - 1.5e-07 29.8 0.4 0.0002 19.5 0.0 3.0 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.15 OAI98341.1 - 1.4e-05 24.6 2.8 1.4e-05 24.6 2.0 2.2 2 0 0 2 2 2 1 WHEP-TRS domain DZR PF12773.2 OAI98341.1 - 0.049 13.4 3.8 0.12 12.1 2.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF4637 PF15470.1 OAI98341.1 - 0.17 11.4 2.5 0.32 10.6 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TF_Zn_Ribbon PF08271.7 OAI98341.1 - 0.76 9.1 5.5 9.5 5.6 1.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2404 PF10296.4 OAI98345.1 - 0.042 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) FAM176 PF14851.1 OAI98345.1 - 0.32 10.6 1.9 0.42 10.2 0.1 1.9 2 0 0 2 2 2 0 FAM176 family DPBB_1 PF03330.13 OAI98346.1 - 0.023 14.6 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TIG PF01833.19 OAI98346.1 - 0.026 14.4 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 IPT/TIG domain Barwin PF00967.12 OAI98346.1 - 0.078 12.6 0.1 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Barwin family Sugar_tr PF00083.19 OAI98347.1 - 1.2e-14 53.7 4.0 1.4e-14 53.5 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAI98347.1 - 2.7e-11 42.8 8.9 2.9e-11 42.6 6.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 OAI98347.1 - 0.0022 17.3 0.8 0.0026 17.0 0.5 1.1 1 0 0 1 1 1 1 Nodulin-like ATG22 PF11700.3 OAI98347.1 - 0.0039 15.7 7.3 0.0045 15.5 5.1 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4401 PF14351.1 OAI98347.1 - 0.0047 15.9 3.0 0.0054 15.7 2.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) MFS_2 PF13347.1 OAI98347.1 - 0.01 14.3 4.4 0.19 10.1 0.0 2.0 2 0 0 2 2 2 2 MFS/sugar transport protein O-antigen_lig PF13425.1 OAI98347.1 - 1.7 8.6 8.9 0.63 10.0 0.1 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein TPR_11 PF13414.1 OAI98348.1 - 1.9e-15 56.2 15.6 1.1e-05 25.0 0.2 7.8 7 1 1 8 8 8 5 TPR repeat TPR_16 PF13432.1 OAI98348.1 - 9.2e-14 51.6 24.5 6.9e-05 23.4 0.9 8.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAI98348.1 - 7.6e-12 45.0 20.9 8.8e-06 25.5 1.8 7.9 4 3 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAI98348.1 - 1.1e-10 40.5 21.1 0.34 10.9 0.0 10.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAI98348.1 - 3e-09 36.0 4.0 1.2 8.8 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAI98348.1 - 4e-08 32.4 0.7 0.7 9.8 0.1 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAI98348.1 - 5.3e-08 32.8 25.2 0.12 13.0 0.1 11.9 8 3 3 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAI98348.1 - 7.2e-08 32.3 11.8 1 9.9 0.1 10.6 11 1 2 13 13 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAI98348.1 - 1.2e-07 30.9 8.7 2.4 8.1 0.1 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAI98348.1 - 5.8e-07 29.7 18.3 1.4e-05 25.2 1.4 6.9 7 1 1 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 OAI98348.1 - 4.7e-06 26.6 10.9 0.0019 18.3 0.4 5.6 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 OAI98348.1 - 0.00037 20.4 1.3 0.99 9.7 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.12 OAI98348.1 - 0.00063 20.0 14.3 0.0071 16.6 0.4 3.8 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_20 PF14561.1 OAI98348.1 - 0.0016 18.5 5.5 0.024 14.7 0.3 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAI98348.1 - 0.0022 17.8 18.5 0.58 10.0 0.2 7.2 4 2 5 9 9 9 2 Tetratricopeptide repeat PPR_3 PF13812.1 OAI98348.1 - 0.003 17.7 1.6 0.73 10.2 0.0 4.9 5 0 0 5 5 5 1 Pentatricopeptide repeat domain TPR_10 PF13374.1 OAI98348.1 - 0.013 15.3 11.0 5 7.2 0.3 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAI98348.1 - 0.022 15.1 9.6 0.58 10.7 0.1 6.3 6 0 0 6 6 4 0 Tetratricopeptide repeat YfhD PF14151.1 OAI98352.1 - 0.023 14.8 0.1 0.067 13.3 0.1 1.8 1 0 0 1 1 1 0 YfhD-like protein FUSC PF04632.7 OAI98352.1 - 0.79 8.0 3.2 0.39 9.1 0.5 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family rve PF00665.21 OAI98353.1 - 3.5e-10 40.0 0.0 7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98354.1 - 2.9e-05 24.4 0.0 6.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI98354.1 - 0.00043 20.0 0.0 0.0013 18.5 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAI98354.1 - 0.0032 17.3 0.0 0.007 16.2 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease MAGE_N PF12440.3 OAI98355.1 - 0.018 15.3 0.9 0.028 14.7 0.6 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Y1_Tnp PF01797.11 OAI98355.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Transposase IS200 like Retrotrans_gag PF03732.12 OAI98356.1 - 0.0092 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein PAT1 PF09770.4 OAI98356.1 - 0.58 8.3 9.8 0.81 7.8 6.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 OAI98356.1 - 4.6 7.0 13.7 0.45 10.3 6.4 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.22 OAI98357.1 - 4.5e-19 68.6 0.0 8.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI98357.1 - 4.2e-05 23.9 0.0 0.00013 22.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98357.1 - 0.00047 20.0 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98357.1 - 0.0058 16.4 0.1 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF3128 PF11326.3 OAI98360.1 - 0.00079 19.4 0.5 0.0013 18.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 OAI98360.1 - 0.0056 16.6 1.7 0.061 13.3 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 OAI98360.1 - 0.0076 16.2 0.8 0.011 15.7 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 OAI98360.1 - 0.011 15.4 2.0 0.016 14.9 1.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 OAI98360.1 - 0.013 15.4 1.6 0.021 14.7 1.1 1.4 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF2051 PF09738.4 OAI98360.1 - 0.29 10.3 4.0 0.38 9.9 2.8 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) CHCH PF06747.8 OAI98360.1 - 0.61 10.0 7.8 4.3 7.3 1.1 2.1 1 1 1 2 2 2 0 CHCH domain WD40 PF00400.27 OAI98361.1 - 4.5e-49 162.6 22.8 9.1e-11 41.2 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 OAI98361.1 - 5.7e-31 107.4 0.0 1.2e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 OAI98361.1 - 0.0034 17.0 0.1 0.09 12.5 0.0 2.6 2 0 0 2 2 2 1 LisH SLD3 PF08639.5 OAI98361.1 - 1.4 7.4 5.1 2 6.9 3.5 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF2051 PF09738.4 OAI98361.1 - 7 5.8 11.8 0.096 11.9 2.8 1.8 3 0 0 3 3 3 0 Double stranded RNA binding protein (DUF2051) Metallophos PF00149.23 OAI98364.1 - 6.3e-41 139.9 0.9 7e-41 139.8 0.1 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PAT1 PF09770.4 OAI98364.1 - 7.1 4.7 21.8 9.8 4.2 15.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UQ_con PF00179.21 OAI98366.1 - 6.9e-39 132.4 0.0 2.2e-34 117.8 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAI98366.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 OAI98366.1 - 0.056 13.3 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain COPI_C PF06957.6 OAI98370.1 - 7.9e-19 67.4 0.0 9e-19 67.2 0.0 1.0 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.9 OAI98371.1 - 2.3e-34 119.0 0.4 2.5e-19 69.4 0.1 2.1 1 1 1 2 2 2 2 Coatomer WD associated region COPI_C PF06957.6 OAI98371.1 - 0.41 9.1 11.6 0.75 8.2 1.9 3.2 3 1 1 4 4 4 0 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.9 OAI98372.1 - 2.1e-13 49.9 0.0 3.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region SMC_hinge PF06470.8 OAI98374.1 - 2e-20 72.9 0.0 6.2e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 OAI98374.1 - 0.014 14.6 14.8 0.052 12.7 2.2 3.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAI98374.1 - 0.027 12.9 58.0 0.014 13.9 17.3 4.2 3 1 1 4 4 4 0 AAA domain SMC_N PF02463.14 OAI98374.1 - 0.38 9.9 31.1 1.1 8.3 21.6 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SlyX PF04102.7 OAI98374.1 - 2 8.8 32.7 0.061 13.6 4.0 6.0 5 1 1 6 6 6 0 SlyX NPV_P10 PF05531.7 OAI98374.1 - 5.4 7.3 23.9 4.3 7.6 2.4 6.5 3 1 3 6 6 6 0 Nucleopolyhedrovirus P10 protein RRN3 PF05327.6 OAI98378.1 - 0.06 11.4 1.5 0.073 11.1 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4611 PF15387.1 OAI98378.1 - 2.3 8.4 10.7 0.65 10.1 4.7 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Hamartin PF04388.7 OAI98384.1 - 0.19 10.3 3.5 0.21 10.2 2.4 1.0 1 0 0 1 1 1 0 Hamartin protein PIF1 PF05970.9 OAI98385.1 - 2.6e-22 79.2 0.0 5.4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI98385.1 - 1.7e-11 44.1 2.8 1.1e-10 41.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain Helitron_like_N PF14214.1 OAI98385.1 - 1.7e-10 40.9 0.3 4.6e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAI98385.1 - 1.7e-06 27.6 4.2 1.1e-05 25.1 0.1 3.3 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activat PF00158.21 OAI98385.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAI98385.1 - 0.083 12.6 0.1 0.37 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1640 PF07798.6 OAI98386.1 - 0.0055 16.7 1.0 0.0083 16.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.13 OAI98386.1 - 0.0091 15.5 0.5 0.013 15.0 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mst1_SARAH PF11629.3 OAI98386.1 - 0.044 13.5 0.4 0.12 12.2 0.1 1.9 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 DUF221 PF02714.10 OAI98391.1 - 2.2e-41 141.7 5.3 3.7e-41 141.0 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 OAI98391.1 - 1.6e-16 60.5 0.0 3.9e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 OAI98391.1 - 4.8e-14 52.1 7.1 2.8e-10 39.9 0.0 3.2 3 1 1 4 4 4 2 Late exocytosis, associated with Golgi transport UPF0118 PF01594.11 OAI98391.1 - 0.0029 16.6 2.7 0.0029 16.6 1.9 2.3 2 1 1 3 3 3 1 Domain of unknown function DUF20 Sm_multidrug_ex PF06695.6 OAI98391.1 - 0.058 13.5 0.0 0.058 13.5 0.0 2.9 4 0 0 4 4 4 0 Putative small multi-drug export protein PP1_bind PF15276.1 OAI98392.1 - 0.86 9.6 3.0 0.47 10.5 0.3 1.9 2 0 0 2 2 2 0 Protein phosphatase 1 binding DUF4158 PF13700.1 OAI98395.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DUF3366 PF11846.3 OAI98402.1 - 0.055 13.3 0.2 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) MULE PF10551.4 OAI98407.1 - 1.6e-07 31.4 0.5 5.4e-07 29.6 0.1 2.1 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAI98407.1 - 0.049 13.1 0.3 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger Transposase_mut PF00872.13 OAI98407.1 - 0.13 10.7 1.8 3.4 6.1 1.3 2.4 1 1 0 1 1 1 0 Transposase, Mutator family Peptidase_C48 PF02902.14 OAI98408.1 - 4.4e-11 42.8 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Lir1 PF07207.6 OAI98408.1 - 0.073 13.2 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Light regulated protein Lir1 Helicase_C PF00271.26 OAI98409.1 - 5e-07 29.4 0.0 1.8e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 OAI98409.1 - 0.00012 22.2 0.6 0.00049 20.2 0.4 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) ResIII PF04851.10 OAI98409.1 - 0.0017 18.2 0.3 0.15 11.8 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAI98409.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Peptidase_C48 PF02902.14 OAI98414.1 - 1e-13 51.3 0.0 1e-13 51.3 0.0 2.8 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.4 OAI98414.1 - 3.5e-08 33.4 0.2 8.1e-07 29.1 0.1 2.7 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAI98414.1 - 0.0022 17.3 0.5 0.0048 16.3 0.4 1.5 1 0 0 1 1 1 1 SWIM zinc finger FlgN PF05130.7 OAI98417.1 - 0.048 13.9 10.2 2 8.6 4.5 2.1 1 1 1 2 2 2 0 FlgN protein Hrs_helical PF12210.3 OAI98417.1 - 4.4 7.6 8.3 9.6 6.5 2.8 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Brr6_like_C_C PF10104.4 OAI98421.1 - 0.0077 15.7 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF1644 PF07800.7 OAI98421.1 - 0.1 12.4 0.4 0.17 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) BAF PF02961.9 OAI98421.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Barrier to autointegration factor Pox_MCEL PF03291.11 OAI98422.1 - 6.1e-70 235.6 0.0 8.2e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 OAI98422.1 - 7.5e-08 32.2 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAI98422.1 - 8.6e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI98422.1 - 3e-07 30.9 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI98422.1 - 9e-07 29.2 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAI98422.1 - 2e-06 28.2 0.0 4.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAI98422.1 - 1.9e-05 24.9 0.0 3.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAI98422.1 - 0.0023 17.9 0.3 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAI98422.1 - 0.0052 15.7 0.0 0.02 13.8 0.0 1.7 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 OAI98422.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PTS_EIIC_2 PF13303.1 OAI98422.1 - 0.071 11.9 2.7 0.12 11.2 1.9 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Ubie_methyltran PF01209.13 OAI98422.1 - 0.11 11.5 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 OAI98422.1 - 0.35 10.2 0.1 0.59 9.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW LRR_4 PF12799.2 OAI98423.1 - 3.2e-34 115.9 29.8 1.2e-07 31.1 0.5 7.1 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAI98423.1 - 2.2e-24 84.9 27.1 4.3e-08 32.7 3.7 5.9 3 1 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 OAI98423.1 - 3.4e-18 62.8 22.6 0.089 12.8 0.0 10.5 10 2 0 10 10 10 8 Leucine Rich Repeat LRR_6 PF13516.1 OAI98423.1 - 5.7e-12 44.3 20.4 0.12 12.5 0.1 10.0 9 2 2 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 OAI98423.1 - 3.1e-11 41.5 22.3 0.39 11.1 0.0 10.5 11 0 0 11 11 11 2 Leucine rich repeat LRR_9 PF14580.1 OAI98423.1 - 6.1e-11 42.1 5.3 0.00011 21.8 0.2 3.7 1 1 2 3 3 3 3 Leucine-rich repeat DHquinase_II PF01220.14 OAI98424.1 - 2.9e-59 198.4 0.0 3.3e-59 198.2 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II PCNA_N PF00705.13 OAI98424.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain CwfJ_C_1 PF04677.10 OAI98427.1 - 1.1e-27 96.1 0.1 1.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAI98427.1 - 6.6e-22 77.8 0.2 1.4e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Zn_clus PF00172.13 OAI98429.1 - 0.0041 17.0 15.5 0.0059 16.4 10.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.1 OAI98431.1 - 1.3e-12 47.5 0.1 3.5e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAI98431.1 - 3.2e-06 26.4 0.1 0.012 14.7 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAI98431.1 - 0.00011 22.0 0.1 0.055 13.2 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAI98431.1 - 0.00019 21.5 0.1 0.002 18.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAI98431.1 - 0.00043 19.3 0.6 0.00043 19.3 0.4 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAI98431.1 - 0.0015 17.4 0.2 0.0015 17.4 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAI98431.1 - 0.052 13.9 0.2 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RNA12 PF10443.4 OAI98432.1 - 7.8e-126 420.0 0.9 2.3e-125 418.4 0.6 1.7 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 OAI98432.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase adh_short PF00106.20 OAI98434.1 - 8.4e-34 116.8 0.4 1.1e-33 116.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI98434.1 - 1.4e-15 57.4 0.1 1.8e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAI98434.1 - 1.7e-14 54.1 0.0 2.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI98434.1 - 0.00013 22.0 1.5 0.0018 18.2 1.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAI98434.1 - 0.0007 19.1 0.1 0.001 18.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 OAI98434.1 - 0.0008 19.1 0.4 0.0019 17.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 OAI98434.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 OAI98434.1 - 0.0015 18.2 0.1 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAI98434.1 - 0.0019 17.3 0.1 0.0041 16.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ChuX_HutX PF06228.8 OAI98434.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX E2F_TDP PF02319.15 OAI98434.1 - 0.037 13.5 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain THF_DHG_CYH_C PF02882.14 OAI98434.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_29 PF13555.1 OAI98434.1 - 0.12 11.9 0.1 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.8 OAI98434.1 - 0.12 11.5 0.4 0.53 9.4 0.0 2.1 3 0 0 3 3 3 0 NmrA-like family ATP_bind_3 PF01171.15 OAI98435.1 - 9.4e-34 116.4 0.0 1.7e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.18 OAI98435.1 - 6.1e-12 45.5 0.0 1.5e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Asn_synthase PF00733.16 OAI98435.1 - 0.00073 19.1 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Asparagine synthase DUF258 PF03193.11 OAI98435.1 - 0.0063 15.7 0.1 0.028 13.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 OAI98435.1 - 0.01 15.7 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAI98435.1 - 0.017 15.4 0.2 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.13 OAI98435.1 - 0.019 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 OAI98435.1 - 0.024 14.6 3.2 3.5 7.5 0.0 3.8 3 1 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 OAI98435.1 - 0.024 14.3 0.1 0.044 13.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 OAI98435.1 - 0.065 14.0 0.0 0.21 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAI98435.1 - 0.09 11.5 0.2 0.19 10.4 0.1 1.4 1 0 0 1 1 1 0 ArgK protein NAD_synthase PF02540.12 OAI98435.1 - 0.11 11.4 0.0 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 NAD synthase AAA_29 PF13555.1 OAI98435.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 OAI98435.1 - 0.24 10.6 0.0 0.44 9.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family RVT_1 PF00078.22 OAI98441.1 - 9.4e-16 57.8 0.0 1.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98441.1 - 1.3e-12 47.8 0.0 4e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98441.1 - 0.00011 22.6 0.0 0.00039 20.8 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98441.1 - 0.0034 17.2 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98441.1 - 0.013 15.2 0.0 0.047 13.5 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 OAI98442.1 - 7.5e-17 61.5 0.0 1.6e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PRCC PF10253.4 OAI98446.1 - 0.094 13.3 4.7 0.12 13.1 3.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MAR_sialic_bdg PF10564.4 OAI98446.1 - 0.15 11.8 12.3 0.17 11.6 1.7 2.5 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat SOG2 PF10428.4 OAI98446.1 - 7.6 5.0 15.7 8.6 4.8 10.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein AIP3 PF03915.8 OAI98447.1 - 0.052 12.4 2.0 0.064 12.1 1.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PAT1 PF09770.4 OAI98447.1 - 0.13 10.4 10.6 0.14 10.3 7.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Allexi_40kDa PF05549.6 OAI98447.1 - 0.26 10.5 1.9 0.33 10.2 1.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pterin_4a PF01329.14 OAI98449.1 - 0.61 9.8 3.5 0.73 9.6 0.2 2.0 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase DUF1183 PF06682.7 OAI98450.1 - 2.6 7.5 7.9 1.2 8.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) PhoD PF09423.5 OAI98451.1 - 8.2e-43 146.6 0.0 1.9e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase HAD_2 PF13419.1 OAI98454.1 - 6.5e-15 55.7 0.0 2.5e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAI98454.1 - 3.6e-12 47.1 0.0 1.4e-11 45.2 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAI98454.1 - 1.6e-07 30.8 0.0 4.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 OAI98454.1 - 0.0045 17.1 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Y_phosphatase2 PF03162.8 OAI98455.1 - 3.8e-30 104.4 0.0 4.2e-23 81.5 0.0 3.2 3 0 0 3 3 3 3 Tyrosine phosphatase family DUF1509 PF07420.6 OAI98456.1 - 0.00027 20.3 3.5 0.00029 20.2 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 OAI98456.1 - 0.0014 17.6 3.3 0.0014 17.6 2.3 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Pap_E4 PF02711.9 OAI98456.1 - 1.1 10.0 4.1 1.6 9.5 2.8 1.2 1 0 0 1 1 1 0 E4 protein GDPD PF03009.12 OAI98457.1 - 3e-30 105.5 0.4 8.1e-30 104.1 0.3 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 OAI98457.1 - 0.0038 17.3 1.5 0.0038 17.3 1.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CoA_trans PF01144.18 OAI98458.1 - 1.1e-104 348.3 0.1 1.5e-62 210.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Asp_Glu_race PF01177.17 OAI98461.1 - 8.2e-27 94.5 0.1 9.8e-27 94.2 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF1077 PF06417.7 OAI98461.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) GTP_EFTU PF00009.22 OAI98462.1 - 1.6e-37 128.7 0.0 2.8e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 OAI98462.1 - 3.3e-37 126.4 0.4 8.2e-37 125.1 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 OAI98462.1 - 4.5e-12 45.9 0.4 1.4e-11 44.3 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAI98462.1 - 0.035 14.0 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3890 PF13029.1 OAI98463.1 - 0.22 11.5 0.9 19 5.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3890) RNase_P_pop3 PF08228.6 OAI98464.1 - 0.0018 18.1 0.3 0.69 9.7 0.0 2.6 3 0 0 3 3 3 2 RNase P subunit Pop3 Dimer_Tnp_hAT PF05699.9 OAI98469.1 - 7e-13 48.0 0.0 2.6e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAI98469.1 - 0.0065 16.2 0.7 0.014 15.1 0.5 1.5 1 0 0 1 1 1 1 BED zinc finger Pkinase PF00069.20 OAI98470.1 - 7.8e-21 74.3 0.0 1.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98470.1 - 2.1e-11 43.3 0.0 7.7e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PIF1 PF05970.9 OAI98476.1 - 2.6e-23 82.5 0.0 4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI98476.1 - 4.7e-11 42.6 0.0 1.5e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAI98476.1 - 1.8e-09 37.5 0.0 4.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAI98476.1 - 9.4e-07 28.4 2.9 1.5e-06 27.8 0.3 2.6 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAI98476.1 - 0.019 14.9 0.0 0.099 12.6 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 OAI98476.1 - 0.05 13.7 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain M_domain PF12938.2 OAI98477.1 - 0.57 9.9 2.5 0.39 10.4 0.5 1.5 2 0 0 2 2 2 0 M domain of GW182 IncA PF04156.9 OAI98478.1 - 0.00013 21.6 4.9 0.00016 21.3 3.4 1.1 1 0 0 1 1 1 1 IncA protein DUF3584 PF12128.3 OAI98478.1 - 0.00015 19.3 2.2 0.00017 19.1 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) GrpE PF01025.14 OAI98478.1 - 0.00025 20.6 1.0 0.00033 20.2 0.7 1.2 1 0 0 1 1 1 1 GrpE HemX PF04375.9 OAI98478.1 - 0.00045 18.9 2.8 0.00066 18.3 1.9 1.3 1 0 0 1 1 1 1 HemX FANCI_S3 PF14677.1 OAI98478.1 - 0.0038 16.6 0.4 0.007 15.7 0.2 1.4 1 1 0 1 1 1 1 FANCI solenoid 3 CENP-F_leu_zip PF10473.4 OAI98478.1 - 0.0049 16.7 1.9 0.0062 16.3 0.9 1.4 2 0 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.7 OAI98478.1 - 0.0064 15.3 0.5 0.0075 15.1 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Dynamitin PF04912.9 OAI98478.1 - 0.0069 15.2 2.7 0.025 13.3 0.8 2.0 1 1 0 2 2 2 1 Dynamitin Apolipoprotein PF01442.13 OAI98478.1 - 0.0099 15.4 2.1 0.014 14.9 1.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2353 PF09789.4 OAI98478.1 - 0.012 14.8 1.6 0.015 14.5 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Exonuc_VII_L PF02601.10 OAI98478.1 - 0.019 14.1 0.7 0.023 13.9 0.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit IFT57 PF10498.4 OAI98478.1 - 0.028 13.1 0.5 0.092 11.4 0.3 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ApoLp-III PF07464.6 OAI98478.1 - 0.052 13.5 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Reo_sigmaC PF04582.7 OAI98478.1 - 0.058 12.5 2.2 3.2 6.8 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAI98478.1 - 0.062 11.7 0.1 0.064 11.7 0.0 1.0 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 OAI98478.1 - 0.067 12.9 0.2 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 Prefoldin subunit Baculo_PEP_C PF04513.7 OAI98478.1 - 0.075 12.8 3.1 0.69 9.7 2.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 OAI98478.1 - 0.088 12.7 5.3 0.11 12.3 3.1 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Syntaxin PF00804.20 OAI98478.1 - 0.11 12.6 1.2 0.17 12.0 0.8 1.4 1 0 0 1 1 1 0 Syntaxin Gp58 PF07902.6 OAI98478.1 - 0.12 10.5 1.7 0.14 10.2 1.2 1.1 1 0 0 1 1 1 0 gp58-like protein DivIC PF04977.10 OAI98478.1 - 0.14 11.6 0.7 0.41 10.1 0.5 1.7 1 1 0 1 1 1 0 Septum formation initiator TraC PF07820.7 OAI98478.1 - 0.14 12.3 2.0 0.16 12.1 0.0 2.1 3 0 0 3 3 2 0 TraC-like protein PEP-utilisers_N PF05524.8 OAI98478.1 - 0.18 11.6 2.3 0.41 10.4 1.6 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Fzo_mitofusin PF04799.8 OAI98478.1 - 0.18 11.1 2.6 0.39 10.0 1.5 1.7 1 1 1 2 2 2 0 fzo-like conserved region DUF3618 PF12277.3 OAI98478.1 - 0.33 11.0 2.5 0.82 9.7 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) 7tm_7 PF08395.7 OAI98478.1 - 0.89 8.5 2.4 1.2 8.0 1.6 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor CorA PF01544.13 OAI98478.1 - 1.1 8.1 4.3 1.4 7.8 2.6 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein rve PF00665.21 OAI98484.1 - 1.5e-11 44.4 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98485.1 - 2.9e-16 59.5 0.0 5.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI98485.1 - 0.00014 22.2 0.0 0.0004 20.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98485.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 OAI98487.1 - 3.2e-19 69.1 0.0 6.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98487.1 - 1.3e-11 44.6 0.0 2.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98487.1 - 0.00046 20.6 0.5 0.0014 19.0 0.1 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI98487.1 - 0.0013 18.6 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease CASP_C PF08172.7 OAI98487.1 - 0.31 10.0 2.8 0.62 9.0 2.0 1.5 1 0 0 1 1 1 0 CASP C terminal MamL-1 PF09596.5 OAI98491.1 - 0.0021 17.8 4.0 0.0076 16.0 2.8 2.0 1 0 0 1 1 1 1 MamL-1 domain DUF972 PF06156.8 OAI98491.1 - 0.93 9.8 22.6 2.6 8.4 0.0 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Shugoshin_N PF07558.6 OAI98491.1 - 2.5 7.8 8.1 0.078 12.7 0.5 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region AAA PF00004.24 OAI98492.1 - 3.7e-44 150.1 0.1 8.9e-44 148.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAI98492.1 - 1.1e-08 34.8 0.1 4e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 OAI98492.1 - 1.9e-07 31.1 0.1 5.2e-07 29.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 OAI98492.1 - 2.3e-06 27.6 0.0 1e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAI98492.1 - 2.9e-06 27.4 0.5 0.002 18.2 0.0 2.8 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 OAI98492.1 - 1.4e-05 24.1 0.0 2.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 OAI98492.1 - 0.00031 20.7 0.1 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 OAI98492.1 - 0.00053 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI98492.1 - 0.00054 19.6 0.1 0.0016 18.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 OAI98492.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 NTPase RuvB_N PF05496.7 OAI98492.1 - 0.0013 17.8 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAI98492.1 - 0.0019 18.9 0.0 0.0083 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 OAI98492.1 - 0.0024 16.6 0.0 0.0053 15.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 OAI98492.1 - 0.0025 17.7 0.0 0.0068 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 OAI98492.1 - 0.0027 17.3 0.1 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAI98492.1 - 0.0029 17.8 0.0 0.016 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAI98492.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 OAI98492.1 - 0.0042 16.2 0.1 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAI98492.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Arch_ATPase PF01637.13 OAI98492.1 - 0.005 16.5 0.6 0.12 12.0 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 OAI98492.1 - 0.0072 15.9 1.0 0.031 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 OAI98492.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAI98492.1 - 0.0094 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin UPF0079 PF02367.12 OAI98492.1 - 0.0097 15.5 0.0 0.026 14.1 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 OAI98492.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAI98492.1 - 0.019 14.5 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAI98492.1 - 0.029 13.7 4.3 0.044 13.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 OAI98492.1 - 0.037 14.3 0.9 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 OAI98492.1 - 0.054 12.3 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 OAI98492.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AFG1_ATPase PF03969.11 OAI98492.1 - 0.075 11.8 0.1 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 OAI98492.1 - 0.11 11.9 0.1 1.7 8.0 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain DAP3 PF10236.4 OAI98492.1 - 0.13 11.1 0.1 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.1 OAI98492.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.17 OAI98493.1 - 2.6e-55 183.9 0.0 1.2e-19 69.6 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI98493.1 - 1.9e-40 136.6 0.0 6.6e-13 48.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI98493.1 - 1.2e-28 98.6 0.0 6.1e-10 38.8 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAI98493.1 - 0.0039 16.9 0.0 8.3 6.2 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Sod_Fe_C PF02777.13 OAI98494.1 - 5.8e-36 122.5 0.1 1.1e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAI98494.1 - 2.1e-32 111.2 2.6 3.6e-32 110.4 1.8 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 OAI98494.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif z-alpha PF02295.12 OAI98494.1 - 0.12 12.1 0.1 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain ATP-synt_DE PF00401.15 OAI98494.1 - 0.29 11.0 3.1 0.74 9.7 0.4 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Herpes_BLLF1 PF05109.8 OAI98499.1 - 2.3 6.0 11.2 2.8 5.7 7.8 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) GTP_EFTU PF00009.22 OAI98506.1 - 4.8e-12 45.6 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Drf_FH1 PF06346.7 OAI98506.1 - 0.0015 18.0 22.4 0.0015 18.0 15.5 4.1 1 1 3 4 4 4 3 Formin Homology Region 1 GTP_EFTU_D3 PF03143.12 OAI98507.1 - 4e-10 39.7 0.0 6.4e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Topoisom_I_N PF02919.10 OAI98510.1 - 8.5e-80 267.0 2.2 8.5e-80 267.0 1.5 3.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 OAI98510.1 - 2e-57 194.0 4.0 2.3e-57 193.8 0.1 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 OAI98510.1 - 1.4e-17 63.1 0.2 2.5e-14 52.6 0.0 3.0 2 0 0 2 2 2 2 C-terminal topoisomerase domain SNARE PF05739.14 OAI98511.1 - 8.2e-17 60.6 1.1 2.8e-16 58.9 0.7 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 OAI98511.1 - 2.6e-14 53.2 4.5 9.5e-14 51.4 0.0 2.8 2 1 0 2 2 2 1 Syntaxin FlaC_arch PF05377.6 OAI98511.1 - 0.0056 16.5 0.9 0.017 14.9 0.2 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 OAI98511.1 - 0.016 15.5 0.9 1.3 9.4 0.0 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.7 OAI98511.1 - 0.047 14.0 1.0 0.26 11.6 0.3 2.6 2 1 0 2 2 2 0 SlyX Peripla_BP_2 PF01497.13 OAI98511.1 - 0.049 12.7 0.8 0.11 11.6 0.5 1.6 1 1 0 1 1 1 0 Periplasmic binding protein DUF148 PF02520.12 OAI98511.1 - 0.052 13.3 1.5 0.43 10.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Lge1 PF11488.3 OAI98511.1 - 0.18 12.0 0.4 11 6.2 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 DUF1664 PF07889.7 OAI98511.1 - 0.19 11.5 1.7 0.72 9.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 OAI98511.1 - 0.25 11.1 6.0 4.9 6.9 0.1 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 OAI98511.1 - 0.74 9.9 3.5 9.5 6.4 0.5 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.16 OAI98511.1 - 3.1 7.3 9.0 0.1 12.0 0.7 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Kelch_3 PF13415.1 OAI98512.1 - 2e-35 120.1 21.5 1.1e-09 38.1 0.1 7.7 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 OAI98512.1 - 2.9e-33 113.2 12.7 2.4e-08 33.7 0.3 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 OAI98512.1 - 1.4e-28 98.3 28.0 8.1e-09 35.1 0.1 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 OAI98512.1 - 2.9e-25 87.5 20.0 6.3e-09 35.2 2.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 OAI98512.1 - 3.1e-24 84.0 10.6 6e-07 29.3 0.6 6.7 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.10 OAI98512.1 - 3.1e-17 61.5 16.6 0.0012 18.5 0.4 7.0 6 1 0 6 6 6 5 Kelch motif Reo_sigmaC PF04582.7 OAI98512.1 - 0.17 11.0 28.0 0.23 10.6 5.1 3.8 2 1 2 4 4 4 0 Reovirus sigma C capsid protein RAG2 PF03089.9 OAI98512.1 - 0.28 9.8 1.6 25 3.4 0.0 3.6 4 1 1 5 5 5 0 Recombination activating protein 2 MSA-2c PF12238.3 OAI98514.1 - 0.0077 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c Ribophorin_II PF05817.9 OAI98514.1 - 0.019 13.1 0.0 0.026 12.7 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II FKBP_N PF01346.13 OAI98514.1 - 0.031 14.3 1.2 0.056 13.4 0.5 1.7 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase V_ATPase_I PF01496.14 OAI98514.1 - 0.042 11.7 0.5 0.052 11.4 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_Tnp_1 PF01527.15 OAI98515.1 - 0.015 15.2 0.1 0.06 13.3 0.0 2.0 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.1 OAI98515.1 - 0.029 14.0 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 OAI98515.1 - 0.045 13.7 0.2 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_17 PF12728.2 OAI98515.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Acetyltransf_6 PF13480.1 OAI98515.1 - 0.12 12.3 0.2 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SSP160 PF06933.6 OAI98515.1 - 2.6 5.9 9.4 3.7 5.3 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Leu_zip PF15294.1 OAI98516.1 - 0.05 12.7 2.3 0.074 12.1 1.6 1.3 1 1 0 1 1 1 0 Leucine zipper DUF2514 PF10721.4 OAI98516.1 - 0.22 11.1 6.5 0.27 10.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DivIVA PF05103.8 OAI98516.1 - 1.3 9.0 5.6 3.2 7.8 0.3 2.0 1 1 1 2 2 2 0 DivIVA protein PhyH PF05721.8 OAI98523.1 - 0.034 14.1 0.0 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) EMP24_GP25L PF01105.19 OAI98524.1 - 3.3e-31 108.4 0.2 4.1e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Jnk-SapK_ap_N PF09744.4 OAI98524.1 - 0.0052 16.7 1.0 0.0065 16.4 0.7 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 PhyH PF05721.8 OAI98526.1 - 1e-08 35.4 0.0 2.3e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HSP90 PF00183.13 OAI98527.1 - 1.4e-26 92.9 0.3 1.6e-26 92.7 0.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HBS1_N PF08938.5 OAI98527.1 - 0.0095 16.0 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 HBS1 N-terminus Cobl PF09469.5 OAI98527.1 - 0.021 14.8 0.2 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain DUF424 PF04242.8 OAI98527.1 - 0.13 12.3 0.1 0.16 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF424) SIR2 PF02146.12 OAI98528.1 - 2.5e-13 50.1 0.0 3.5e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF2458 PF10454.4 OAI98528.1 - 0.022 14.6 0.4 0.029 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF4449 PF14613.1 OAI98529.1 - 1.8e-10 41.0 0.0 3.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) GATA PF00320.22 OAI98529.1 - 0.00059 19.1 2.0 0.0012 18.1 1.4 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF3602 PF12223.3 OAI98529.1 - 0.071 13.4 11.5 0.3 11.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) DUF3505 PF12013.3 OAI98530.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Dimer_Tnp_hAT PF05699.9 OAI98534.1 - 3e-17 62.0 0.6 6.3e-17 60.9 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAI98535.1 - 1.5e-48 165.2 0.0 2e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98535.1 - 8.5e-28 97.1 0.0 1.2e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI98535.1 - 3.8e-10 39.2 0.0 2.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAI98535.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ROKNT PF08067.6 OAI98535.1 - 0.63 9.9 2.6 1.5 8.7 1.8 1.6 1 0 0 1 1 1 0 ROKNT (NUC014) domain RVT_1 PF00078.22 OAI98536.1 - 5.9e-19 68.2 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98536.1 - 4.3e-15 55.8 0.0 9.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98536.1 - 0.012 16.0 0.2 0.1 13.1 0.0 2.6 3 0 0 3 3 3 0 Aspartyl protease DUF3275 PF11679.3 OAI98537.1 - 0.22 11.0 10.8 0.052 13.1 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) GAS PF13851.1 OAI98541.1 - 0.00015 21.0 9.8 0.00021 20.5 6.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 OAI98541.1 - 0.0093 15.7 12.8 0.013 15.2 8.9 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 OAI98541.1 - 0.025 14.3 21.2 0.081 12.7 14.7 1.7 1 1 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 OAI98541.1 - 0.026 13.7 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4200 PF13863.1 OAI98541.1 - 0.051 13.5 16.2 0.038 13.9 7.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) SPT16 PF08644.6 OAI98541.1 - 0.068 13.0 3.2 0.058 13.2 1.6 1.5 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) CENP-F_leu_zip PF10473.4 OAI98541.1 - 0.071 12.9 16.5 0.19 11.6 2.2 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 OAI98541.1 - 0.076 13.2 0.4 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.10 OAI98541.1 - 0.16 11.5 12.0 0.18 11.2 3.5 2.4 1 1 2 3 3 3 0 Septum formation initiator DUF904 PF06005.7 OAI98541.1 - 0.22 11.8 12.9 0.32 11.2 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Fib_alpha PF08702.5 OAI98541.1 - 0.28 11.3 5.6 1.1 9.3 2.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 OAI98541.1 - 0.51 9.2 10.6 0.64 8.9 7.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 OAI98541.1 - 0.86 7.8 14.0 1.1 7.5 9.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 OAI98541.1 - 1 9.7 10.9 2.6 8.4 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Adeno_PIX PF03955.9 OAI98541.1 - 1.1 9.8 5.9 5.6 7.5 0.7 2.4 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) TMF_TATA_bd PF12325.3 OAI98541.1 - 1.3 8.7 17.3 3.7 7.3 5.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2968 PF11180.3 OAI98541.1 - 1.3 8.3 15.3 1.3 8.3 7.7 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) CENP-Q PF13094.1 OAI98541.1 - 4.7 7.2 15.8 20 5.1 11.0 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Jnk-SapK_ap_N PF09744.4 OAI98541.1 - 5 7.1 11.7 4.4 7.2 7.1 1.5 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 OAI98541.1 - 6.7 6.2 16.7 49 3.4 11.6 1.9 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 OAI98541.1 - 7.1 5.5 12.9 9.6 5.1 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.2 OAI98541.1 - 7.2 6.7 7.9 4.9 7.3 1.3 2.7 2 1 0 2 2 2 0 Central kinetochore-associated FUSC PF04632.7 OAI98541.1 - 7.6 4.8 6.6 9.2 4.5 4.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family eIF3_N PF09440.5 OAI98541.1 - 9.2 6.4 8.9 9.1 6.4 0.4 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Spt5_N PF11942.3 OAI98545.1 - 0.61 10.7 14.1 0.094 13.3 4.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Host_attach PF10116.4 OAI98545.1 - 9.9 6.3 16.9 0.13 12.4 1.1 3.1 3 0 0 3 3 3 0 Protein required for attachment to host cells F-box-like PF12937.2 OAI98546.1 - 0.00074 19.1 0.7 0.0021 17.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like PQ-loop PF04193.9 OAI98547.1 - 2.5e-09 36.5 6.0 2.5e-09 36.5 4.2 2.0 2 0 0 2 2 2 1 PQ loop repeat DUF1345 PF07077.6 OAI98547.1 - 0.052 13.0 0.4 0.077 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) YrhC PF14143.1 OAI98547.1 - 0.41 10.6 3.4 0.31 11.0 0.3 2.0 2 0 0 2 2 2 0 YrhC-like protein WD40 PF00400.27 OAI98548.1 - 1.5e-55 183.1 25.1 1.1e-10 40.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 OAI98548.1 - 2.5e-13 50.1 0.5 8.2e-07 28.9 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAI98548.1 - 0.015 13.6 0.0 0.031 12.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 OAI98548.1 - 0.073 11.8 0.0 0.16 10.7 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region KfrA_N PF11740.3 OAI98549.1 - 0.63 10.4 7.8 0.22 11.9 3.2 1.8 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Aminotran_3 PF00202.16 OAI98550.1 - 9.5e-85 284.4 0.0 1.2e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NDK PF00334.14 OAI98551.1 - 0.0002 21.1 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase LRR_6 PF13516.1 OAI98555.1 - 1.4e-12 46.2 28.1 0.32 11.1 0.0 10.6 11 0 0 11 11 11 5 Leucine Rich repeat LRR_4 PF12799.2 OAI98555.1 - 1.3e-05 24.7 23.4 0.00034 20.1 0.3 6.6 3 2 3 8 8 8 3 Leucine Rich repeats (2 copies) GAT PF03127.9 OAI98555.1 - 1.8e-05 24.5 0.0 0.00018 21.4 0.0 2.6 1 1 0 1 1 1 1 GAT domain LRR_1 PF00560.28 OAI98555.1 - 0.00032 20.3 17.5 15 6.0 0.1 8.7 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 OAI98555.1 - 0.0054 16.4 19.4 2.3 8.0 0.3 5.7 3 1 4 7 7 7 3 Leucine rich repeat Cofilin_ADF PF00241.15 OAI98556.1 - 4.5e-41 139.6 0.2 5.1e-41 139.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 OAI98556.1 - 0.053 13.5 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain Gly_rich PF12810.2 OAI98557.1 - 0.00059 19.4 37.7 0.0022 17.6 26.0 1.8 1 1 0 1 1 1 1 Glycine rich protein TPR_12 PF13424.1 OAI98558.1 - 1.5e-31 108.1 21.9 1e-05 25.3 0.7 8.0 6 2 2 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 OAI98558.1 - 4e-21 74.2 16.8 0.014 15.3 0.4 11.1 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAI98558.1 - 7.1e-11 41.1 3.9 6.2 7.0 0.3 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI98558.1 - 4.9e-08 32.5 12.0 0.11 12.1 0.1 5.7 6 0 0 6 6 5 3 TPR repeat TPR_14 PF13428.1 OAI98558.1 - 1.6e-07 31.2 12.4 7.2 7.5 0.0 10.3 9 3 3 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAI98558.1 - 6.9e-07 28.6 0.1 2.8 7.7 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TcdB_N PF12918.2 OAI98558.1 - 0.00027 20.9 0.9 12 6.1 0.0 5.0 3 1 1 4 4 4 0 TcdB toxin N-terminal helical domain TPR_8 PF13181.1 OAI98558.1 - 0.00033 20.2 4.1 13 5.8 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI98558.1 - 0.0011 19.5 19.2 7.2 7.4 0.9 7.4 6 3 3 9 9 7 1 Tetratricopeptide repeat DUF3856 PF12968.2 OAI98558.1 - 0.0014 18.4 10.7 0.71 9.6 0.5 4.8 3 2 3 6 6 6 2 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 OAI98558.1 - 0.0017 18.1 2.8 6.2 6.7 0.0 4.6 5 1 0 5 5 4 1 Anaphase-promoting complex subunit 5 PPR_3 PF13812.1 OAI98558.1 - 0.0058 16.8 1.4 6.2 7.3 0.0 5.2 5 0 0 5 5 4 1 Pentatricopeptide repeat domain T2SG PF08334.6 OAI98558.1 - 0.034 13.8 1.2 24 4.7 0.0 4.4 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein G TPR_7 PF13176.1 OAI98558.1 - 3.6 7.6 9.0 1.5e+02 2.5 0.0 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Occludin_ELL PF07303.8 OAI98558.1 - 3.9 8.2 5.6 2.1e+02 2.7 0.2 4.3 2 1 4 6 6 5 0 Occludin homology domain TPR_19 PF14559.1 OAI98558.1 - 9.1 6.7 17.0 1.6 9.1 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat UDPG_MGDP_dh_N PF03721.9 OAI98561.1 - 1.4e-48 164.7 0.0 5e-48 162.9 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 OAI98561.1 - 9e-26 89.9 0.0 1.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 OAI98561.1 - 9e-23 80.4 0.0 2.5e-22 79.0 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.10 OAI98561.1 - 7.4e-05 22.6 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 OAI98561.1 - 0.0044 17.0 1.2 0.074 13.0 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 OAI98561.1 - 0.0097 15.6 0.0 0.038 13.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_31 PF13847.1 OAI98561.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ANT PF03374.9 OAI98561.1 - 0.073 13.1 0.0 7.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain Pyr_redox PF00070.22 OAI98561.1 - 0.082 13.3 0.4 1 9.8 0.0 3.0 4 1 1 5 5 5 0 Pyridine nucleotide-disulphide oxidoreductase DUF2624 PF11116.3 OAI98561.1 - 0.089 13.3 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Bac_transf PF02397.11 OAI98562.1 - 1.9e-31 108.6 0.0 2.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial sugar transferase Epimerase PF01370.16 OAI98562.1 - 3.2e-18 66.0 0.0 4.6e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAI98562.1 - 5e-11 41.8 0.0 7e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAI98562.1 - 5.2e-10 38.6 0.0 7.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 OAI98562.1 - 1.1e-06 27.7 0.0 1.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 OAI98562.1 - 9.1e-05 21.4 0.0 0.0015 17.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAI98562.1 - 0.00033 20.7 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding GST_N_3 PF13417.1 OAI98566.1 - 4.7e-15 55.5 0.0 1.1e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 OAI98566.1 - 4.9e-12 45.8 0.0 8.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAI98566.1 - 4.9e-11 42.4 0.0 9.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAI98566.1 - 0.023 15.1 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NIR_SIR PF01077.17 OAI98568.1 - 9e-46 155.0 0.0 2e-37 127.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 OAI98568.1 - 9.6e-29 98.8 0.0 3.8e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 OAI98568.1 - 1e-25 90.4 0.0 2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 OAI98568.1 - 9.7e-10 38.3 0.1 4.2e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg YwhD PF08741.5 OAI98568.1 - 0.18 11.2 0.1 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 YwhD family NDUF_B7 PF05676.8 OAI98569.1 - 3.2e-27 93.7 1.2 4.7e-27 93.1 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 OAI98569.1 - 0.0013 18.4 2.2 0.002 17.8 1.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Mak16 PF04874.9 OAI98573.1 - 0.005 16.9 1.8 0.0073 16.3 1.3 1.2 1 0 0 1 1 1 1 Mak16 protein C-terminal region RNA_pol_3_Rpc31 PF11705.3 OAI98573.1 - 0.48 10.3 21.5 0.6 10.0 14.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GCR1_C PF12550.3 OAI98574.1 - 3.7e-19 68.3 2.1 7.2e-19 67.4 1.5 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAI98574.1 - 0.18 12.0 4.9 3.4 7.8 0.0 4.1 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain Transposase_21 PF02992.9 OAI98576.1 - 3.3e-18 65.6 0.0 5.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Brr6_like_C_C PF10104.4 OAI98580.1 - 0.0033 16.9 0.6 0.0046 16.4 0.4 1.4 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DpnD-PcfM PF14207.1 OAI98582.1 - 0.0066 16.1 0.4 0.013 15.2 0.3 1.5 1 0 0 1 1 1 1 DpnD/PcfM-like protein DUF4475 PF14753.1 OAI98582.1 - 0.016 14.7 1.9 0.025 14.1 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) PyrI_C PF02748.10 OAI98582.1 - 0.15 11.4 0.9 0.33 10.4 0.6 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS1595 PF12760.2 OAI98582.1 - 1.8 8.4 5.3 3.1 7.6 3.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain SSP160 PF06933.6 OAI98587.1 - 0.74 7.7 15.5 1 7.2 10.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 OAI98587.1 - 3 7.0 12.9 4.5 6.4 8.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 OAI98588.1 - 0.63 9.8 13.0 0.77 9.5 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 OAI98588.1 - 2.4 7.8 9.4 3.4 7.3 6.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) vMSA PF00695.14 OAI98588.1 - 2.8 7.0 16.3 4.7 6.3 11.3 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Macoilin PF09726.4 OAI98588.1 - 8.7 4.4 12.2 11 4.1 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Chitin_synth_2 PF03142.10 OAI98589.1 - 9.9e-244 809.6 0.0 1.3e-243 809.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 OAI98589.1 - 9.8e-108 361.0 0.0 1.8e-107 360.1 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAI98589.1 - 8.8e-17 61.4 4.2 8.8e-17 61.4 2.9 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAI98589.1 - 9e-17 61.6 0.0 6.2e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAI98589.1 - 3.6e-15 55.5 0.1 6.7e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 OAI98589.1 - 4.2e-13 48.8 0.0 3.6e-11 42.6 0.1 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAI98589.1 - 1.9e-09 37.4 0.0 9.6e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAI98589.1 - 6.5e-07 28.7 0.0 1.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Peptidase_S64 PF08192.6 OAI98593.1 - 0.46 8.7 8.0 0.56 8.4 5.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 EspB PF05802.6 OAI98593.1 - 0.48 9.3 28.8 0.67 8.8 20.0 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Med3 PF11593.3 OAI98593.1 - 1.1 8.4 17.6 1.3 8.1 12.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2884 PF11101.3 OAI98593.1 - 1.5 8.1 7.7 0.11 11.8 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) PIF1 PF05970.9 OAI98598.1 - 1.1e-27 96.9 0.0 4.5e-26 91.6 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAI98598.1 - 2.1e-11 43.8 0.7 4.3e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAI98598.1 - 4e-07 29.6 0.3 1.3e-06 28.0 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAI98598.1 - 2.8e-05 24.2 0.0 9.1e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 OAI98598.1 - 0.00021 21.3 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.1 OAI98598.1 - 0.00038 20.1 0.0 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAI98598.1 - 0.0028 17.6 0.4 0.013 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 OAI98598.1 - 0.003 17.1 0.2 0.68 9.4 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RXT2_N PF08595.6 OAI98598.1 - 0.0059 16.4 1.0 0.011 15.5 0.7 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal NTPase_1 PF03266.10 OAI98598.1 - 0.0062 16.2 0.3 0.12 12.1 0.1 2.3 2 0 0 2 2 2 1 NTPase T2SE PF00437.15 OAI98598.1 - 0.01 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 OAI98598.1 - 0.012 15.3 0.0 0.13 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 OAI98598.1 - 0.038 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 OAI98598.1 - 0.063 11.0 0.1 0.11 10.2 0.0 1.3 1 0 0 1 1 1 0 Helicase PhoH PF02562.11 OAI98598.1 - 0.11 11.6 0.1 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.14 OAI98598.1 - 0.12 11.8 0.1 0.82 9.0 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nucleoplasmin PF03066.10 OAI98598.1 - 0.17 11.3 6.2 0.39 10.2 4.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin RNA_helicase PF00910.17 OAI98598.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase FAM176 PF14851.1 OAI98598.1 - 0.4 10.3 6.4 0.71 9.5 1.2 2.3 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 OAI98598.1 - 2.6 8.4 10.5 0.85 9.9 4.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Antimicrobial10 PF08105.6 OAI98601.1 - 6.3 6.4 8.4 3.8 7.2 0.3 2.8 3 0 0 3 3 3 0 Metchnikowin family PCI PF01399.22 OAI98607.1 - 5.2e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 1 0 1 1 1 1 PCI domain JSRP PF15312.1 OAI98607.1 - 0.57 10.1 2.7 3.2 7.7 0.1 2.9 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein LRR_6 PF13516.1 OAI98608.1 - 0.014 15.3 4.9 79 3.8 0.1 6.4 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 OAI98608.1 - 0.23 11.1 7.7 30 4.3 0.1 6.1 7 2 1 8 8 8 0 Leucine Rich repeats (2 copies) DUF2545 PF10810.3 OAI98609.1 - 0.061 13.7 0.6 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) UDPGT PF00201.13 OAI98612.1 - 8.5e-13 47.6 0.1 1.2e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 OAI98612.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 OAI98612.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 OAI98613.1 - 3.7e-15 55.4 0.1 6.5e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 OAI98613.1 - 0.027 13.6 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 1 MFS_3 PF05977.8 OAI98613.1 - 0.042 11.9 0.0 0.075 11.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Yos1 PF08571.5 OAI98614.1 - 6.1e-27 93.5 5.0 9e-27 92.9 3.5 1.3 1 1 0 1 1 1 1 Yos1-like DUF1212 PF06738.7 OAI98616.1 - 1.5e-39 135.4 1.1 1.5e-39 135.4 0.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAI98616.1 - 3.2e-16 59.4 6.0 3.2e-16 59.4 4.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) EB1 PF03271.12 OAI98617.1 - 5.6e-16 58.3 0.2 9.9e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 OAI98617.1 - 5.2e-07 29.6 0.1 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain GCR1_C PF12550.3 OAI98622.1 - 3.9e-20 71.4 2.7 4.2e-20 71.4 0.6 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Apolipoprotein PF01442.13 OAI98622.1 - 0.0032 17.0 1.7 0.0059 16.1 1.2 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ALS2CR8 PF15299.1 OAI98622.1 - 0.018 14.6 0.6 0.035 13.6 0.4 1.4 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Acyl-CoA_dh_C PF12806.2 OAI98622.1 - 0.11 12.3 3.3 0.37 10.6 0.2 2.8 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Plant_tran PF04827.9 OAI98624.1 - 0.0016 17.9 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.1 OAI98624.1 - 0.0025 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Lipase_bact_N PF12262.3 OAI98627.1 - 0.039 13.1 0.5 0.059 12.5 0.4 1.2 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal CMD PF02627.15 OAI98627.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family PIF1 PF05970.9 OAI98629.1 - 4.6e-21 75.1 0.0 7.8e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI98629.1 - 2.5e-10 40.2 0.2 2.4e-09 37.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 OAI98629.1 - 1.8e-08 33.9 1.7 1.2e-07 31.3 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAI98629.1 - 0.0029 17.6 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 OAI98629.1 - 0.01 15.4 0.5 0.7 9.4 0.0 2.7 2 1 0 3 3 3 0 AAA domain Helicase_RecD PF05127.9 OAI98629.1 - 0.026 14.1 0.3 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 Helicase Torsin PF06309.6 OAI98629.1 - 0.034 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_5 PF07728.9 OAI98629.1 - 0.039 13.6 0.4 0.13 11.9 0.3 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 OAI98629.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.24 OAI98629.1 - 0.058 12.8 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 OAI98629.1 - 0.092 12.8 0.1 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain MbeD_MobD PF04899.7 OAI98636.1 - 0.07 13.0 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 MbeD/MobD like Retrotrans_gag PF03732.12 OAI98636.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAI98637.1 - 1.4e-18 67.0 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98637.1 - 1.8e-13 50.6 0.0 3.7e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98637.1 - 0.001 19.5 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98637.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease APG9 PF04109.11 OAI98642.1 - 1e-150 501.7 0.0 1.3e-150 501.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 ABC_tran PF00005.22 OAI98643.1 - 1.3e-47 161.5 0.3 6.7e-23 81.4 0.0 2.9 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 OAI98643.1 - 3.6e-21 76.4 1.6 5.4e-05 23.2 0.0 4.2 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 OAI98643.1 - 3.1e-20 71.7 3.1 3.1e-20 71.7 2.1 2.3 3 0 0 3 3 1 1 ABC transporter AAA_23 PF13476.1 OAI98643.1 - 6.8e-10 39.6 6.6 0.0023 18.2 0.5 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAI98643.1 - 3.7e-09 35.9 0.4 0.003 17.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 OAI98643.1 - 8.7e-09 34.9 1.9 0.29 10.3 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAI98643.1 - 2.1e-08 34.3 0.0 0.0035 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 OAI98643.1 - 2.5e-07 31.5 0.7 0.017 15.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAI98643.1 - 5.7e-07 29.7 0.3 0.0088 16.1 0.0 3.4 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.1 OAI98643.1 - 8.4e-07 29.0 0.0 0.041 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAI98643.1 - 1.6e-06 27.4 7.8 0.02 13.9 0.0 4.8 4 2 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 OAI98643.1 - 2e-06 28.3 0.0 0.11 12.9 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_18 PF13238.1 OAI98643.1 - 2.5e-06 27.8 0.5 0.038 14.2 0.0 3.2 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 OAI98643.1 - 4e-06 26.7 0.0 0.025 14.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 OAI98643.1 - 9.5e-06 24.8 0.0 0.018 14.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 OAI98643.1 - 7.8e-05 22.3 0.3 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.1 OAI98643.1 - 0.00012 21.9 0.1 0.13 12.2 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 OAI98643.1 - 0.00013 21.8 1.8 1.3 8.8 0.0 4.0 4 1 1 5 5 5 2 Dynamin family MobB PF03205.9 OAI98643.1 - 0.00017 21.3 3.8 0.67 9.6 0.0 3.7 3 1 1 4 4 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAI98643.1 - 0.00019 21.3 0.0 0.57 10.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 OAI98643.1 - 0.00023 20.6 0.4 0.081 12.3 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 OAI98643.1 - 0.00031 19.7 0.1 0.25 10.2 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA PF00004.24 OAI98643.1 - 0.00063 19.9 0.3 0.38 10.9 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 OAI98643.1 - 0.00064 18.5 0.0 0.22 10.2 0.0 2.7 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 OAI98643.1 - 0.00066 19.1 0.1 1 8.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 OAI98643.1 - 0.00098 18.6 0.1 1.1 8.7 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_14 PF13173.1 OAI98643.1 - 0.00098 19.0 0.0 6 6.7 0.0 4.0 3 1 1 4 4 4 0 AAA domain AAA_5 PF07728.9 OAI98643.1 - 0.0011 18.6 0.4 1.5 8.5 0.1 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 OAI98643.1 - 0.0013 18.9 1.5 1.3 9.2 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.1 OAI98643.1 - 0.0016 18.0 1.0 0.38 10.2 0.1 3.1 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.17 OAI98643.1 - 0.002 17.0 0.0 0.86 8.4 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Arch_ATPase PF01637.13 OAI98643.1 - 0.0028 17.3 1.5 0.29 10.7 0.0 3.3 3 1 0 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 OAI98643.1 - 0.0032 16.9 0.2 3.1 7.1 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain Septin PF00735.13 OAI98643.1 - 0.0036 16.3 1.0 6.4 5.7 0.0 3.3 3 0 0 3 3 3 0 Septin ATP-synt_ab PF00006.20 OAI98643.1 - 0.0067 15.9 0.0 1.2 8.6 0.0 2.7 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FeoB_N PF02421.13 OAI98643.1 - 0.011 15.0 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.10 OAI98643.1 - 0.014 15.1 2.5 5.8 6.5 0.1 3.5 4 0 0 4 4 3 0 NTPase Sigma54_activ_2 PF14532.1 OAI98643.1 - 0.016 15.2 0.0 0.86 9.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.4 OAI98643.1 - 0.018 14.5 0.7 0.73 9.3 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 OAI98643.1 - 0.045 13.1 0.0 9 5.6 0.0 2.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF87 PF01935.12 OAI98643.1 - 0.23 11.2 8.6 1.5 8.5 0.1 4.0 4 1 1 5 5 4 0 Domain of unknown function DUF87 AAA_13 PF13166.1 OAI98643.1 - 1.3 7.3 10.2 3.3 6.0 0.0 3.6 4 1 0 4 4 4 0 AAA domain MRP-L27 PF09809.4 OAI98644.1 - 2e-06 27.3 0.7 4.1e-05 23.1 0.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cation_ATPase_C PF00689.16 OAI98648.1 - 1.5e-07 31.1 1.2 1.6e-07 31.0 0.8 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Asp PF00026.18 OAI98649.1 - 6.4e-17 61.7 1.6 8.4e-17 61.3 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.1 OAI98649.1 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 OAI98649.1 - 0.023 14.6 0.7 0.054 13.4 0.1 2.0 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAI98649.1 - 0.072 13.5 0.2 0.82 10.2 0.0 2.4 1 1 2 3 3 3 0 Aspartyl protease Rrn6 PF10214.4 OAI98650.1 - 3.2 5.7 10.7 4 5.4 7.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SR-25 PF10500.4 OAI98650.1 - 7.6 5.9 29.7 13 5.1 20.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 OAI98650.1 - 8.2 4.7 15.5 8.9 4.6 10.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cation_ATPase_N PF00690.21 OAI98651.1 - 1.6e-09 37.0 0.0 2.5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAI98652.1 - 9.3e-06 25.5 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit JmjC PF02373.17 OAI98659.1 - 2.7e-12 46.9 0.0 7.1e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF4400 PF14348.1 OAI98659.1 - 0.063 12.6 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) FYVE PF01363.16 OAI98659.1 - 1.3 8.9 6.6 0.34 10.8 1.7 2.1 2 0 0 2 2 2 0 FYVE zinc finger Zn_Tnp_IS91 PF14319.1 OAI98659.1 - 1.8 8.0 7.9 3.5 7.1 2.9 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Helicase_C PF00271.26 OAI98660.1 - 1e-11 44.5 0.0 2.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAI98660.1 - 3.4e-09 36.4 0.0 7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase His_Phos_2 PF00328.17 OAI98663.1 - 2.4e-30 106.0 0.0 3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CsbD PF05532.7 OAI98664.1 - 4.4e-15 55.0 8.6 1.2e-10 40.8 3.6 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 OAI98664.1 - 0.0024 17.9 0.7 0.0064 16.5 0.2 1.8 1 1 1 2 2 2 1 Heat shock protein 9/12 DUF1495 PF07381.6 OAI98664.1 - 0.052 13.2 0.1 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) LPP20 PF02169.11 OAI98664.1 - 1.2 9.2 4.2 6.2 6.9 2.9 1.8 1 1 0 1 1 1 0 LPP20 lipoprotein zf-FCS PF06467.9 OAI98665.1 - 0.011 15.3 3.1 0.022 14.4 2.1 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TnpB_IS66 PF05717.8 OAI98665.1 - 0.076 12.4 0.0 1.8 8.0 0.0 2.6 3 0 0 3 3 3 0 IS66 Orf2 like protein ATP-synt_ab PF00006.20 OAI98667.1 - 3e-62 209.9 0.0 4.1e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAI98667.1 - 1.4e-16 60.9 0.0 3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAI98667.1 - 3.3e-12 46.4 0.3 5.9e-12 45.6 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAI98667.1 - 0.00099 18.9 0.2 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 OAI98667.1 - 0.047 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) DUF4604 PF15377.1 OAI98668.1 - 5.6e-19 68.8 15.2 7.3e-19 68.5 10.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF1675 PF07897.6 OAI98668.1 - 0.24 11.2 13.1 0.3 10.9 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S49_N PF08496.5 OAI98668.1 - 0.89 9.3 9.7 0.74 9.5 3.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.3 OAI98668.1 - 1.1 9.6 7.9 3.8 7.8 2.9 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal rve PF00665.21 OAI98671.1 - 0.0078 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain FUSC PF04632.7 OAI98671.1 - 0.2 10.0 0.7 0.24 9.7 0.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family RVT_1 PF00078.22 OAI98673.1 - 1.3e-18 67.1 0.0 2.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98673.1 - 5.4e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98674.1 - 1.5e-19 70.2 0.0 2.9e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.24 OAI98680.1 - 2.6e-40 138.2 0.1 4.1e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAI98680.1 - 6.7e-15 55.2 0.2 1.2e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Dynamitin PF04912.9 OAI98683.1 - 2.2e-05 23.4 2.0 0.00026 19.9 0.4 2.0 2 0 0 2 2 2 1 Dynamitin ADIP PF11559.3 OAI98683.1 - 0.00041 20.2 1.6 0.0023 17.8 1.0 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding GrpE PF01025.14 OAI98683.1 - 0.00085 18.9 0.4 0.0011 18.4 0.3 1.2 1 0 0 1 1 1 1 GrpE APG17 PF04108.7 OAI98683.1 - 0.0017 17.2 0.5 0.0021 16.9 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 Tmemb_cc2 PF10267.4 OAI98683.1 - 0.0054 15.3 0.4 0.0069 15.0 0.2 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein DUF3584 PF12128.3 OAI98683.1 - 0.0054 14.1 1.1 0.0061 13.9 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HemX PF04375.9 OAI98683.1 - 0.0069 15.0 1.8 0.009 14.6 1.3 1.2 1 0 0 1 1 1 1 HemX Reo_sigmaC PF04582.7 OAI98683.1 - 0.0099 15.0 4.4 1 8.4 0.1 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 OAI98683.1 - 0.01 14.3 0.1 0.01 14.3 0.0 1.0 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 OAI98683.1 - 0.015 15.0 1.6 0.13 12.0 0.7 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 OAI98683.1 - 0.021 14.3 2.6 0.029 13.9 1.8 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 OAI98683.1 - 0.023 14.4 2.1 0.074 12.8 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2353 PF09789.4 OAI98683.1 - 0.025 13.8 1.7 0.031 13.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.1 OAI98683.1 - 0.029 13.5 0.1 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3618 PF12277.3 OAI98683.1 - 0.046 13.7 2.1 0.098 12.7 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF1002 PF06207.6 OAI98683.1 - 0.056 12.7 0.2 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Borrelia_lipo_1 PF05714.6 OAI98683.1 - 0.061 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein LXG PF04740.7 OAI98683.1 - 0.082 12.6 1.6 0.11 12.2 1.1 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Exonuc_VII_L PF02601.10 OAI98683.1 - 0.088 11.9 1.4 0.11 11.6 1.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gp58 PF07902.6 OAI98683.1 - 0.099 10.8 1.1 0.11 10.6 0.7 1.2 1 0 0 1 1 1 0 gp58-like protein DUF148 PF02520.12 OAI98683.1 - 0.1 12.3 0.3 0.48 10.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF148 CHDCT2 PF08074.6 OAI98683.1 - 0.13 12.0 0.8 0.18 11.5 0.6 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain PEP-utilisers_N PF05524.8 OAI98683.1 - 0.23 11.2 1.4 0.53 10.1 1.0 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal CorA PF01544.13 OAI98683.1 - 0.26 10.2 3.7 0.34 9.8 2.3 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein PIF1 PF05970.9 OAI98686.1 - 6.8e-23 81.1 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI98686.1 - 1.8e-11 43.9 0.0 5.9e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAI98686.1 - 1.2e-09 38.2 0.0 2.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAI98686.1 - 2.7e-07 30.2 1.3 1.5e-06 27.8 0.1 2.8 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAI98686.1 - 0.022 14.7 0.0 0.1 12.6 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 OAI98686.1 - 0.074 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RFX5_DNA_bdg PF14621.1 OAI98687.1 - 0.0012 18.4 2.8 0.0014 18.3 1.9 1.1 1 0 0 1 1 1 1 RFX5 DNA-binding domain AT_hook PF02178.14 OAI98687.1 - 0.056 13.1 3.4 0.16 11.7 2.4 1.8 1 0 0 1 1 1 0 AT hook motif RHD3 PF05879.7 OAI98689.1 - 1.7e-29 102.3 0.5 2.2e-29 102.0 0.4 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) RVT_1 PF00078.22 OAI98694.1 - 2.5e-16 59.6 0.0 4.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI98694.1 - 5.2e-12 45.9 0.0 1.5e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98694.1 - 0.00035 21.0 0.1 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI98694.1 - 0.039 13.8 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI98694.1 - 0.053 13.3 0.1 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HNH PF01844.18 OAI98694.1 - 0.37 10.7 0.5 1.1 9.2 0.3 1.8 1 0 0 1 1 1 0 HNH endonuclease NDUF_B7 PF05676.8 OAI98695.1 - 0.15 11.4 0.4 0.45 9.9 0.1 1.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MULE PF10551.4 OAI98701.1 - 1.1e-18 67.1 0.0 2.4e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAI98701.1 - 9.1e-11 41.1 0.1 9.1e-11 41.1 0.1 1.8 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.13 OAI98701.1 - 2.8e-07 29.4 0.0 5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family TPK_catalytic PF04263.11 OAI98701.1 - 0.085 12.4 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain zf-BED PF02892.10 OAI98702.1 - 0.09 12.5 0.3 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger AAA_19 PF13245.1 OAI98703.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 OAI98703.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UPF0079 PF02367.12 OAI98703.1 - 0.0034 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 OAI98703.1 - 0.0048 16.4 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 OAI98703.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase T2SE PF00437.15 OAI98703.1 - 0.07 12.0 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 OAI98703.1 - 0.093 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 OAI98703.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Nup96 PF12110.3 OAI98707.1 - 6.6e-79 265.0 0.0 9.1e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 OAI98707.1 - 1.8e-40 138.0 0.0 3.3e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 OAI98707.1 - 1.1e-32 112.6 385.0 1.3e-07 31.8 27.0 12.2 4 2 8 12 12 12 9 Nucleoporin FG repeat region Daxx PF03344.10 OAI98707.1 - 1.7 7.0 7.5 2.5 6.4 5.2 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 OAI98707.1 - 7.5 4.3 12.2 11 3.7 8.5 1.1 1 0 0 1 1 1 0 Nop14-like family RCC1 PF00415.13 OAI98708.1 - 4.2e-32 110.1 1.6 4.8e-05 23.4 0.0 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAI98708.1 - 1.7e-26 91.1 20.3 3.9e-07 29.4 0.3 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Fe-ADH PF00465.14 OAI98709.1 - 4.2e-92 308.6 0.0 5.3e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAI98709.1 - 9.1e-13 48.0 0.0 5.2e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase SH3_9 PF14604.1 OAI98710.1 - 0.00039 19.9 0.0 0.018 14.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 OAI98710.1 - 0.0016 17.8 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Proteasome PF00227.21 OAI98711.1 - 1.3e-59 200.7 0.0 2e-59 200.0 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 OAI98711.1 - 2.8e-10 39.2 0.2 7.7e-10 37.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature NifU_N PF01592.11 OAI98712.1 - 1.6e-52 176.7 0.1 2.4e-52 176.1 0.1 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain RVT_2 PF07727.9 OAI98717.1 - 4.9e-68 228.7 0.0 6.2e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pkinase PF00069.20 OAI98720.1 - 9.9e-12 44.5 0.0 2.8e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98720.1 - 4.8e-08 32.3 0.0 0.0071 15.4 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 OAI98720.1 - 3.5e-05 22.9 0.1 8.9e-05 21.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAI98720.1 - 0.043 13.5 1.1 0.095 12.4 0.8 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Apolipoprotein PF01442.13 OAI98722.1 - 0.013 15.0 5.0 0.023 14.2 3.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 OAI98722.1 - 0.018 14.2 3.6 0.021 14.0 2.5 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 OAI98722.1 - 0.041 12.1 4.1 0.043 12.1 2.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Syntaxin_2 PF14523.1 OAI98722.1 - 0.044 13.8 2.9 0.041 13.9 1.2 1.6 2 0 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.7 OAI98722.1 - 0.074 12.8 3.0 0.11 12.2 0.4 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF883 PF05957.8 OAI98722.1 - 0.45 10.9 5.4 1.8 8.9 1.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DASH_Dad2 PF08654.5 OAI98722.1 - 0.99 9.4 7.5 0.8 9.7 1.1 2.6 1 1 1 3 3 3 0 DASH complex subunit Dad2 OmpH PF03938.9 OAI98722.1 - 3 7.7 7.4 8 6.3 3.6 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mito_carr PF00153.22 OAI98723.1 - 1.5e-60 200.8 2.9 1.5e-22 79.0 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1370 PF07114.6 OAI98723.1 - 0.06 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) Voltage_CLC PF00654.15 OAI98724.1 - 1.6e-90 303.6 31.0 3.1e-90 302.7 21.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 OAI98724.1 - 0.00039 20.1 0.0 0.00093 18.9 0.0 1.6 1 0 0 1 1 1 1 CBS domain CENP-Q PF13094.1 OAI98728.1 - 0.00038 20.5 1.6 0.23 11.4 0.7 2.3 1 1 1 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 OAI98728.1 - 0.0078 16.0 2.6 0.016 15.0 1.9 1.5 1 1 0 1 1 1 1 Tropomyosin like DUF2968 PF11180.3 OAI98728.1 - 0.0094 15.3 5.2 0.0094 15.3 3.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 OAI98728.1 - 0.011 14.9 1.2 0.013 14.6 0.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 OAI98728.1 - 0.017 15.2 0.9 0.025 14.6 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BBP1_C PF15272.1 OAI98728.1 - 0.022 14.3 2.4 0.018 14.6 0.9 1.4 2 0 0 2 2 1 0 Spindle pole body component BBP1, C-terminal DUF1993 PF09351.5 OAI98728.1 - 0.025 14.5 2.4 0.043 13.7 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DivIVA PF05103.8 OAI98728.1 - 0.029 14.4 4.8 0.075 13.0 3.3 1.7 1 1 0 1 1 1 0 DivIVA protein Tropomyosin PF00261.15 OAI98728.1 - 0.036 13.1 6.6 0.25 10.3 2.5 2.4 2 1 0 2 2 2 0 Tropomyosin Filament PF00038.16 OAI98728.1 - 0.063 12.7 5.9 0.074 12.5 3.1 1.7 2 0 0 2 2 2 0 Intermediate filament protein Fmp27_WPPW PF10359.4 OAI98728.1 - 0.064 11.6 2.8 0.077 11.3 2.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.7 OAI98728.1 - 0.065 13.0 0.6 0.11 12.2 0.4 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 OAI98728.1 - 0.066 12.5 9.1 0.3 10.3 6.2 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Mnd1 PF03962.10 OAI98728.1 - 0.11 12.1 2.3 0.18 11.4 1.6 1.3 1 0 0 1 1 1 0 Mnd1 family TMF_DNA_bd PF12329.3 OAI98728.1 - 0.16 11.8 5.5 0.81 9.5 0.9 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ax_dynein_light PF10211.4 OAI98728.1 - 0.17 11.7 3.1 0.24 11.2 2.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain Cep57_MT_bd PF06657.8 OAI98728.1 - 0.86 9.5 6.1 3.5 7.6 3.3 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Phage_lysis PF03245.8 OAI98728.1 - 1 9.3 10.1 0.47 10.4 4.1 2.3 1 1 2 3 3 3 0 Bacteriophage Rz lysis protein DUF4140 PF13600.1 OAI98728.1 - 3.8 8.0 7.9 3.2 8.2 0.2 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) NTP_transf_2 PF01909.18 OAI98729.1 - 0.0026 18.0 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Dimer_Tnp_hAT PF05699.9 OAI98730.1 - 2.1e-14 52.8 0.0 4.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Daxx PF03344.10 OAI98730.1 - 0.0025 16.3 22.1 0.0025 16.3 15.3 2.3 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 OAI98730.1 - 0.35 8.7 36.1 0.0054 14.7 15.9 2.7 3 0 0 3 3 3 0 Nop14-like family Herpes_TAF50 PF03326.8 OAI98730.1 - 1.7 7.4 6.9 5.2 5.9 3.3 2.4 3 0 0 3 3 3 0 Herpesvirus transcription activation factor (transactivator) Pkinase PF00069.20 OAI98733.1 - 5.2e-47 160.1 0.0 7.1e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98733.1 - 3e-22 78.9 0.0 6.3e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI98733.1 - 1.2e-10 40.7 0.0 2.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAI98733.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDCD2_C PF04194.8 OAI98735.1 - 1.8 8.1 3.6 0.48 10.0 0.2 1.6 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain BH3 PF15285.1 OAI98736.1 - 0.042 13.3 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Dimer_Tnp_hAT PF05699.9 OAI98739.1 - 2e-15 56.1 0.1 5.7e-15 54.7 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.21 OAI98744.1 - 1.8e-11 44.1 0.0 4.9e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAI98747.1 - 0.019 15.4 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.15 OAI98747.1 - 0.024 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease SDA1 PF05285.7 OAI98751.1 - 0.045 13.0 10.5 0.055 12.7 7.3 1.0 1 0 0 1 1 1 0 SDA1 DDE_1 PF03184.14 OAI98755.1 - 2.3e-24 85.7 0.0 3.9e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAI98755.1 - 7.9e-05 22.4 0.8 0.00015 21.5 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease PV_NSP1 PF12433.3 OAI98755.1 - 0.034 14.2 0.2 0.46 10.5 0.0 2.7 3 0 0 3 3 3 0 Parvovirus non-structural protein 1 IMD PF08397.6 OAI98755.1 - 0.048 12.9 9.3 0.077 12.2 6.5 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain RNase_H2-Ydr279 PF09468.5 OAI98755.1 - 3.2 6.8 8.9 4.8 6.2 6.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 OAI98755.1 - 3.8 7.2 7.1 5.7 6.6 4.9 1.3 1 0 0 1 1 1 0 DDHD domain Lipase_3 PF01764.20 OAI98759.1 - 9.6e-11 41.4 0.0 5.6e-10 38.9 0.0 2.0 1 1 1 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAI98759.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1034 PF06280.7 OAI98760.1 - 3.9e-11 43.3 3.7 5.2e-11 42.9 0.3 2.2 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Big_2 PF02368.13 OAI98760.1 - 0.0051 16.6 0.3 0.0051 16.6 0.2 2.6 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 2) Motile_Sperm PF00635.21 OAI98760.1 - 0.0063 16.1 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD_N PF00345.15 OAI98760.1 - 0.046 13.4 0.1 0.093 12.5 0.1 1.4 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Fn3-like PF14310.1 OAI98760.1 - 0.062 13.2 0.2 2.7 7.9 0.0 2.9 2 1 1 3 3 3 0 Fibronectin type III-like domain NPCBM_assoc PF10633.4 OAI98760.1 - 9 6.4 8.7 9.8 6.3 1.8 3.3 3 2 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FAD_binding_4 PF01565.18 OAI98761.1 - 1.7e-19 69.6 3.1 3.3e-19 68.7 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAI98761.1 - 0.00023 20.9 0.3 0.00063 19.6 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like MRP-S22 PF10245.4 OAI98761.1 - 0.22 10.8 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 DUF1554 PF07588.6 OAI98762.1 - 0.16 11.4 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) DPBB_1 PF03330.13 OAI98763.1 - 0.0088 16.0 0.2 0.022 14.7 0.1 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel CGGC PF08821.6 OAI98763.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 CGGC domain Peptidase_S8 PF00082.17 OAI98764.1 - 4.7e-36 124.3 2.2 7.2e-36 123.7 1.5 1.3 1 0 0 1 1 1 1 Subtilase family RPT PF13446.1 OAI98764.1 - 0.12 11.7 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 A repeated domain in UCH-protein DNA_pol_viral_C PF00336.13 OAI98768.1 - 0.033 13.4 0.8 0.056 12.6 0.1 1.6 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain rve PF00665.21 OAI98769.1 - 1.5e-18 67.0 0.0 3.6e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI98769.1 - 2.4e-15 56.4 0.0 5.4e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAI98769.1 - 0.00018 20.9 0.0 0.0016 17.8 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAI98769.1 - 0.0019 18.0 1.9 0.0019 18.0 1.3 2.0 2 0 0 2 2 2 1 Zinc knuckle Nitro_FeMo-Co PF02579.12 OAI98769.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor zf-CCHC_4 PF14392.1 OAI98769.1 - 0.26 10.9 1.7 0.77 9.4 1.2 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF2268 PF10026.4 OAI98769.1 - 0.66 9.3 2.3 0.86 8.9 0.3 2.0 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) Phage_integrase PF00589.17 OAI98770.1 - 1.7e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family 6PGD PF00393.14 OAI98772.1 - 1.4e-82 277.1 0.0 2e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 OAI98772.1 - 4.1e-31 108.0 0.0 8.3e-31 107.0 0.0 1.5 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAI98772.1 - 0.017 15.5 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 OAI98772.1 - 0.037 14.1 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.7 OAI98772.1 - 0.087 12.1 0.0 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Ub-Mut7C PF14451.1 OAI98772.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 Mut7-C ubiquitin UBN2_2 PF14227.1 OAI98774.1 - 2.2e-12 46.5 0.0 3.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAI98774.1 - 2.5e-11 43.0 0.0 4.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAI98774.1 - 2.9e-08 33.5 0.0 4.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAI98774.1 - 2e-06 27.4 3.8 4.3e-06 26.3 2.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAI98774.1 - 0.056 13.1 3.5 0.46 10.1 1.4 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.1 OAI98774.1 - 1.3 8.7 5.9 2.8 7.6 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_S8 PF00082.17 OAI98778.1 - 3.3e-37 128.1 4.4 5.2e-37 127.5 3.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAI98778.1 - 2.4e-13 50.4 0.3 7.9e-13 48.7 0.2 2.0 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Motile_Sperm PF00635.21 OAI98778.1 - 0.019 14.5 0.4 0.079 12.6 0.1 2.1 2 0 0 2 2 2 0 MSP (Major sperm protein) domain PapD_N PF00345.15 OAI98778.1 - 0.11 12.2 0.2 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Baculo_PEP_C PF04513.7 OAI98779.1 - 0.00011 22.0 8.9 0.0072 16.1 0.2 3.2 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 OAI98779.1 - 0.022 14.7 1.1 0.022 14.7 0.8 2.6 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PIN_2 PF10130.4 OAI98779.1 - 0.041 13.9 1.1 0.93 9.5 0.1 2.5 2 1 0 2 2 2 0 PIN domain Taxilin PF09728.4 OAI98779.1 - 0.28 10.2 5.3 2.1 7.3 0.5 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Myosin_tail_1 PF01576.14 OAI98779.1 - 0.42 8.2 7.6 0.59 7.7 1.1 2.1 2 0 0 2 2 2 0 Myosin tail AAA_13 PF13166.1 OAI98779.1 - 0.63 8.4 7.1 1 7.7 3.3 1.9 1 1 1 2 2 2 0 AAA domain PilJ PF13675.1 OAI98779.1 - 1.4 9.2 6.3 2.9 8.2 1.5 2.6 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nup54 PF13874.1 OAI98779.1 - 2.9 7.5 7.8 37 3.9 0.0 3.2 2 1 2 4 4 4 0 Nucleoporin complex subunit 54 Mnd1 PF03962.10 OAI98779.1 - 3.3 7.3 7.7 2.9 7.5 0.5 2.2 2 0 0 2 2 2 0 Mnd1 family ATP-synt_B PF00430.13 OAI98779.1 - 7.9 6.2 11.1 0.071 12.9 0.4 2.5 2 2 1 3 3 3 0 ATP synthase B/B' CF(0) MT-A70 PF05063.9 OAI98780.1 - 1.2e-48 164.9 0.0 1.1e-32 112.9 0.0 2.3 2 0 0 2 2 2 2 MT-A70 Methyltransf_26 PF13659.1 OAI98780.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MGC-24 PF05283.6 OAI98780.1 - 1.2 8.8 4.4 0.28 10.9 0.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) SET PF00856.23 OAI98781.1 - 4e-21 76.0 0.0 1.9e-20 73.8 0.0 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 OAI98781.1 - 2.7e-06 27.5 2.4 2.7e-06 27.5 1.7 2.0 2 0 0 2 2 2 1 Pre-SET motif DUF2431 PF10354.4 OAI98783.1 - 6.6e-32 110.7 0.0 1.1e-28 100.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) RXT2_N PF08595.6 OAI98783.1 - 0.023 14.4 0.2 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TRAP_alpha PF03896.11 OAI98783.1 - 0.075 12.0 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit S-antigen PF05756.6 OAI98783.1 - 0.17 11.8 2.4 0.35 10.8 1.7 1.4 1 0 0 1 1 1 0 S-antigen protein PBP1_TM PF14812.1 OAI98783.1 - 3.2 8.1 15.1 0.047 14.0 3.9 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 OAI98783.1 - 5.4 7.3 8.7 12 6.2 6.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DPBB_1 PF03330.13 OAI98784.1 - 2.4e-08 33.8 0.1 3.5e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAI98784.1 - 0.0066 16.1 1.0 0.011 15.3 0.7 1.6 1 1 0 1 1 1 1 Barwin family zf-RING_3 PF14369.1 OAI98784.1 - 0.034 14.1 0.5 0.066 13.2 0.4 1.4 1 0 0 1 1 1 0 zinc-finger DIM PF08194.7 OAI98784.1 - 0.047 13.6 0.3 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 DIM protein PPR_2 PF13041.1 OAI98785.1 - 9.7e-14 51.0 0.4 0.0026 17.7 0.0 5.1 6 0 0 6 6 6 3 PPR repeat family PPR_3 PF13812.1 OAI98785.1 - 2.4e-06 27.3 6.1 1.5 9.3 0.0 6.7 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 OAI98785.1 - 0.0042 16.9 5.6 3.9 7.6 0.1 5.1 6 0 0 6 6 6 1 PPR repeat AA_synth PF06684.6 OAI98785.1 - 0.018 14.4 0.1 0.033 13.5 0.1 1.4 1 0 0 1 1 1 0 Amino acid synthesis DUF755 PF05501.6 OAI98785.1 - 2 8.4 14.5 0.2 11.7 2.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Pex16 PF08610.5 OAI98786.1 - 1.2e-76 257.9 0.0 2.5e-59 200.9 0.0 3.2 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) Pro_dh PF01619.13 OAI98787.1 - 1.7e-34 119.2 0.0 1e-16 60.8 0.0 3.7 2 1 1 3 3 3 3 Proline dehydrogenase Cutinase PF01083.17 OAI98797.1 - 1.2e-24 87.0 0.1 1.5e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAI98797.1 - 0.0068 15.8 0.1 0.0093 15.4 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 OAI98797.1 - 0.017 15.3 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.7 OAI98797.1 - 0.049 13.1 0.1 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Cutinase PF01083.17 OAI98798.1 - 4.6e-24 85.1 0.1 5.5e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.8 OAI98798.1 - 0.0018 17.7 0.1 0.0038 16.6 0.0 1.5 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 OAI98798.1 - 0.032 13.9 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI98798.1 - 0.066 12.7 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 OAI98799.1 - 1.3e-29 103.2 0.0 1.5e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 OAI98799.1 - 1.3e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_1 PF00561.15 OAI98799.1 - 0.00014 21.5 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 OAI98799.1 - 0.01 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 OAI98799.1 - 0.019 14.7 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 OAI98799.1 - 0.026 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) FSH1 PF03959.8 OAI98799.1 - 0.03 13.7 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 OAI98799.1 - 0.032 14.4 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 OAI98799.1 - 0.05 12.9 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.9 OAI98799.1 - 0.091 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF726 PF05277.7 OAI98799.1 - 0.095 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Cutinase PF01083.17 OAI98802.1 - 3e-12 46.6 0.0 3.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 OAI98802.1 - 0.051 13.3 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPP_enzyme_N PF02776.13 OAI98803.1 - 1e-34 119.5 0.1 1.4e-34 119.0 0.1 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAI98803.1 - 2.5e-26 92.0 0.0 9.6e-26 90.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cutinase PF01083.17 OAI98805.1 - 7.3e-22 77.9 0.0 9.1e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.8 OAI98805.1 - 0.0053 16.2 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 OAI98805.1 - 0.058 13.1 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_C23 PF05379.6 OAI98809.1 - 0.19 11.7 1.0 7.3 6.6 0.1 2.7 2 0 0 2 2 2 0 Carlavirus endopeptidase Phage_integrase PF00589.17 OAI98810.1 - 4.7e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Phage integrase family Brr6_like_C_C PF10104.4 OAI98811.1 - 3.8e-35 120.3 0.0 5.3e-35 119.8 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.10 OAI98811.1 - 9.7 6.2 7.3 4.2 7.4 0.0 2.9 3 1 0 3 3 3 0 Ctr copper transporter family RVT_3 PF13456.1 OAI98812.1 - 0.0037 17.0 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like TRP PF06011.7 OAI98815.1 - 1e-75 254.9 12.6 1.7e-75 254.3 8.8 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 OAI98815.1 - 2.1e-29 102.3 0.1 3e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 OAI98815.1 - 0.063 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 ML domain Septin PF00735.13 OAI98816.1 - 2.8e-124 413.6 0.2 2.8e-124 413.6 0.1 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAI98816.1 - 4.9e-07 29.7 0.0 1.3e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAI98816.1 - 2.4e-06 26.8 0.0 6e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAI98816.1 - 2e-05 24.1 0.7 0.00051 19.5 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAI98816.1 - 0.00029 20.2 0.3 0.0032 16.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 OAI98816.1 - 0.00041 19.8 0.0 0.00065 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 OAI98816.1 - 0.0012 19.2 0.3 0.021 15.3 0.0 2.8 3 1 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 OAI98816.1 - 0.0016 18.6 0.0 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.11 OAI98816.1 - 0.002 17.2 1.4 0.0039 16.3 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Arch_ATPase PF01637.13 OAI98816.1 - 0.0033 17.1 1.7 1.5 8.4 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase ABC_tran PF00005.22 OAI98816.1 - 0.0033 17.7 7.1 0.65 10.2 4.9 2.6 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 OAI98816.1 - 0.0036 17.1 6.1 0.061 13.1 0.0 3.3 2 2 1 3 3 3 1 Dynamin family AAA_16 PF13191.1 OAI98816.1 - 0.004 17.1 0.3 0.022 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 OAI98816.1 - 0.0081 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 OAI98816.1 - 0.03 14.5 0.1 0.36 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 OAI98816.1 - 0.03 14.0 0.1 0.1 12.2 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 OAI98816.1 - 0.031 13.8 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAI98816.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 OAI98816.1 - 0.061 12.8 0.1 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 OAI98816.1 - 0.11 11.9 2.2 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 OAI98816.1 - 0.19 10.8 7.2 0.4 9.8 5.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_5 PF07728.9 OAI98816.1 - 0.19 11.4 1.7 1.5 8.5 0.0 2.9 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) YlqD PF11068.3 OAI98816.1 - 0.37 10.8 8.7 1.1 9.3 6.0 1.8 1 0 0 1 1 1 0 YlqD protein DUF87 PF01935.12 OAI98816.1 - 0.39 10.4 5.3 2 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 OAI98816.1 - 1.3 7.7 3.3 11 4.6 0.0 2.4 2 0 0 2 2 2 0 ArgK protein IncA PF04156.9 OAI98816.1 - 2 8.0 8.2 3.6 7.1 5.7 1.4 1 0 0 1 1 1 0 IncA protein ATP_bind_1 PF03029.12 OAI98816.1 - 2.2 7.7 4.6 19 4.6 0.0 3.1 4 1 0 4 4 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.6 OAI98816.1 - 4 7.3 5.8 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Ras PF00071.17 OAI98817.1 - 1.1e-51 174.4 0.1 1.6e-51 173.9 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI98817.1 - 2.2e-15 57.1 0.0 4.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAI98817.1 - 1e-10 41.1 0.0 2.4e-10 39.9 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAI98817.1 - 2.2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAI98817.1 - 0.00019 20.9 0.1 0.00064 19.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAI98817.1 - 0.003 16.8 0.0 0.0067 15.6 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 OAI98817.1 - 0.0084 15.9 0.1 0.018 14.8 0.1 2.0 1 1 0 1 1 1 1 Dynamin family SLX9 PF15341.1 OAI98817.1 - 0.092 13.1 0.5 0.092 13.1 0.4 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 PWWP PF00855.12 OAI98818.1 - 3.8e-15 55.8 0.3 3.8e-15 55.8 0.2 2.6 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.6 OAI98818.1 - 1e-06 28.1 1.1 1.8e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Toxin_40 PF15520.1 OAI98818.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 40 SOBP PF15279.1 OAI98818.1 - 8.5 6.6 11.0 12 6.2 7.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Vps26 PF03643.10 OAI98819.1 - 2.7e-130 433.1 3.7 3e-130 432.9 2.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 OAI98819.1 - 0.0035 17.1 1.5 0.17 11.6 0.1 3.3 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Shisa PF13908.1 OAI98820.1 - 0.065 13.4 0.2 0.065 13.4 0.2 2.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 OAI98821.1 - 1.8e-45 155.2 47.1 5.8e-45 153.5 32.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TFIIA PF03153.8 OAI98822.1 - 1.7e-46 159.8 11.1 1.9e-27 97.1 3.8 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 OAI98822.1 - 0.47 8.6 2.8 0.51 8.5 2.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_32N PF00251.15 OAI98826.1 - 5.5e-41 140.9 0.6 8e-38 130.5 0.4 3.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAI98826.1 - 2.4e-12 47.0 0.0 5.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal TYA PF01021.14 OAI98826.1 - 0.046 13.9 0.5 0.046 13.9 0.4 1.9 2 0 0 2 2 2 0 TYA transposon protein Pkinase PF00069.20 OAI98827.1 - 8e-75 251.3 0.1 1.5e-74 250.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98827.1 - 8.1e-53 179.1 1.3 9.7e-53 178.8 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 OAI98827.1 - 4.6e-22 78.1 0.8 3.8e-20 72.0 0.0 3.0 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 OAI98827.1 - 3.1e-09 36.9 1.3 6.8e-09 35.8 0.9 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 OAI98827.1 - 8.9e-07 28.1 0.0 1.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 OAI98827.1 - 0.00063 19.9 0.7 0.13 12.4 0.1 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain APH PF01636.18 OAI98827.1 - 0.00068 19.4 3.1 0.011 15.4 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1777 PF08648.7 OAI98827.1 - 0.0039 16.9 13.8 0.01 15.5 9.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) SAPS PF04499.10 OAI98827.1 - 1.3 7.5 4.4 2.4 6.7 3.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMgT PF10270.4 OAI98828.1 - 4.2e-19 68.9 0.0 4.7e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter ALIX_LYPXL_bnd PF13949.1 OAI98829.1 - 0.36 9.7 1.9 0.43 9.4 0.6 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Sugar_tr PF00083.19 OAI98830.1 - 7.3e-66 222.5 13.6 8.7e-66 222.3 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAI98830.1 - 3.9e-14 52.1 19.9 3.9e-14 52.1 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2721 PF11026.3 OAI98830.1 - 0.13 11.9 5.1 0.87 9.2 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) ESSS PF10183.4 OAI98830.1 - 0.14 12.5 0.1 0.57 10.6 0.0 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Leader_Erm PF08253.6 OAI98830.1 - 0.16 11.4 0.2 0.35 10.3 0.1 1.5 1 0 0 1 1 1 0 Erm Leader peptide DASH_Spc34 PF08657.5 OAI98831.1 - 0.42 10.2 4.7 0.6 9.7 3.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF4632 PF15451.1 OAI98832.1 - 0.061 13.2 0.1 0.061 13.2 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) BSP_II PF05432.6 OAI98837.1 - 0.014 14.7 4.4 0.023 13.9 3.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-BED PF02892.10 OAI98838.1 - 0.0085 15.8 0.8 0.02 14.6 0.5 1.6 1 0 0 1 1 1 1 BED zinc finger Pkinase PF00069.20 OAI98839.1 - 7.5e-27 94.1 0.0 1.5e-26 93.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98839.1 - 7e-13 48.2 0.0 8.8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAI98839.1 - 0.00032 20.5 0.2 0.00066 19.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAI98839.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dimer_Tnp_hAT PF05699.9 OAI98840.1 - 8.4e-17 60.5 0.2 1.2e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-FokI_C PF09254.6 OAI98840.1 - 0.13 11.3 0.2 0.16 11.0 0.1 1.3 1 1 0 1 1 1 0 Restriction endonuclease FokI, C terminal Pkinase PF00069.20 OAI98841.1 - 1.9e-45 155.0 0.0 3e-45 154.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98841.1 - 2.9e-22 78.9 0.0 4.3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI98841.1 - 4.6e-07 29.0 0.0 1.3e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAI98841.1 - 7.2e-05 22.6 1.1 0.016 14.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAI98841.1 - 0.0024 16.9 0.1 0.0039 16.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 OAI98841.1 - 0.0059 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 OAI98841.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 OAI98841.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Astacin PF01400.19 OAI98845.1 - 7.4e-05 22.2 2.8 0.32 10.3 2.2 3.0 2 1 0 2 2 2 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 OAI98845.1 - 0.022 14.4 5.4 0.035 13.8 1.6 2.6 2 1 0 2 2 2 0 Matrixin TPR_12 PF13424.1 OAI98847.1 - 1.6e-05 24.7 19.8 0.034 14.0 0.1 5.8 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAI98847.1 - 0.00065 19.2 0.2 0.6 9.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAI98847.1 - 0.0051 16.5 1.4 18 5.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 OAI98847.1 - 0.038 13.7 0.2 1 9.1 0.0 2.8 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_2 PF07719.12 OAI98847.1 - 1.4 8.9 19.3 0.93 9.5 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Zn_clus PF00172.13 OAI98852.1 - 8.2e-05 22.4 9.4 0.00014 21.6 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3 PF10243.4 OAI98852.1 - 0.00015 20.3 17.5 0.00015 20.3 12.1 1.9 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 Abhydrolase_6 PF12697.2 OAI98853.1 - 7.2e-24 84.9 0.7 7.2e-24 84.9 0.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI98853.1 - 5e-23 81.8 0.0 1e-22 80.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAI98853.1 - 3.8e-13 49.4 0.4 5.5e-12 45.6 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 OAI98853.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.7 OAI98853.1 - 0.21 10.1 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Asp PF00026.18 OAI98854.1 - 2.9e-24 85.8 0.0 6.6e-19 68.2 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI98854.1 - 0.00028 20.8 0.1 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.18 OAI98855.1 - 6.1e-53 180.1 4.6 1.2e-52 179.2 3.2 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI98855.1 - 9.3e-07 28.9 0.4 1.8e-05 24.7 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAI98855.1 - 0.0095 15.4 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 OAI98856.1 - 4e-46 157.7 0.0 6.7e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAI98856.1 - 3.9e-05 23.6 1.8 0.00017 21.5 0.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAI98856.1 - 0.16 11.4 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal TPR_12 PF13424.1 OAI98859.1 - 1.5e-06 28.0 4.9 1.5e-05 24.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAI98859.1 - 0.00011 21.8 2.6 0.45 10.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAI98859.1 - 0.00011 21.6 0.2 0.3 10.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI98859.1 - 0.00016 21.2 1.7 0.0039 16.8 0.1 3.4 4 0 0 4 4 4 1 TPR repeat TPR_9 PF13371.1 OAI98859.1 - 0.0069 16.2 0.5 1.6 8.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAI98859.1 - 0.032 13.9 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAI98860.1 - 0.064 13.1 17.6 0.34 10.8 0.1 7.0 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAI98860.1 - 8.8 6.0 20.3 1 9.0 1.5 6.5 6 2 1 8 8 8 0 TPR repeat MIT PF04212.13 OAI98862.1 - 0.011 15.5 7.0 0.058 13.2 0.8 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 OAI98862.1 - 0.1 12.5 11.5 1.1 9.2 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAI98864.1 - 8.5e-06 25.6 19.4 0.19 11.7 0.1 6.7 6 1 0 6 6 6 5 Tetratricopeptide repeat HEAT_2 PF13646.1 OAI98865.1 - 1.5e-05 25.1 0.6 0.087 13.1 0.0 3.4 2 1 0 3 3 3 2 HEAT repeats NUC173 PF08161.7 OAI98865.1 - 0.00026 20.3 0.1 0.57 9.4 0.0 3.2 2 1 1 3 3 3 1 NUC173 domain HEAT_EZ PF13513.1 OAI98865.1 - 0.00088 19.6 0.0 0.036 14.5 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 OAI98865.1 - 0.0021 18.0 1.2 17 5.8 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 OAI98865.1 - 0.028 14.7 0.0 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 OAI98865.1 - 0.097 12.5 0.1 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 OAI98872.1 - 4.3e-28 98.1 0.0 1.2e-27 96.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98872.1 - 8.6e-15 54.4 0.0 1.1e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 OAI98872.1 - 0.0052 16.3 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 OAI98872.1 - 0.0076 16.0 1.2 0.012 15.3 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAI98872.1 - 0.064 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_Tnp_4 PF13359.1 OAI98873.1 - 3.7e-10 39.6 0.0 5.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HhH-GPD PF00730.20 OAI98878.1 - 1.6e-13 50.9 0.1 2.5e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PG_binding_2 PF08823.6 OAI98878.1 - 0.013 15.5 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WW PF00397.21 OAI98879.1 - 1.3e-08 34.5 4.0 0.0019 18.0 0.0 3.2 3 0 0 3 3 3 2 WW domain Formyl_trans_N PF00551.14 OAI98880.1 - 4.9e-30 104.4 0.0 6.5e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 OAI98880.1 - 3.1e-08 32.9 0.0 6.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 OAI98880.1 - 8.5e-05 22.1 0.1 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 ACT domain Sulfolobus_pRN PF05584.6 OAI98880.1 - 0.28 11.1 1.4 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 Sulfolobus plasmid regulatory protein DUF3722 PF12519.3 OAI98881.1 - 7.2e-83 277.7 0.0 2.8e-82 275.8 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 OAI98881.1 - 0.00027 20.3 0.1 0.0015 17.9 0.0 2.2 3 0 0 3 3 3 1 Eukaryotic porin FAD_binding_1 PF00667.15 OAI98882.1 - 1.1e-29 103.4 0.0 1.7e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAI98882.1 - 4.1e-27 94.9 0.0 1.4e-26 93.2 0.0 1.9 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 OAI98882.1 - 3.1e-11 43.8 0.0 8.7e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 OAI98882.1 - 0.0038 16.6 0.0 0.14 11.5 0.0 2.6 3 0 0 3 3 3 1 Flavodoxin domain Flavodoxin_5 PF12724.2 OAI98882.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain TIP120 PF08623.5 OAI98883.1 - 4.1e-50 169.6 0.2 4.1e-50 169.6 0.1 3.9 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 OAI98883.1 - 3.2e-23 81.8 27.8 0.0046 17.2 0.1 9.4 7 4 2 9 9 8 8 HEAT repeats HEAT PF02985.17 OAI98883.1 - 1.5e-13 49.5 22.0 0.64 10.2 0.1 12.5 14 0 0 14 14 12 4 HEAT repeat Adaptin_N PF01602.15 OAI98883.1 - 1.7e-08 33.2 21.7 6.6e-05 21.4 0.1 6.3 1 1 5 6 6 6 3 Adaptin N terminal region HEAT_EZ PF13513.1 OAI98883.1 - 2.9e-07 30.7 49.9 0.74 10.3 0.0 14.1 10 4 7 17 17 17 4 HEAT-like repeat UME PF08064.8 OAI98883.1 - 5.2e-06 26.3 2.3 2.1 8.3 0.0 6.0 5 1 2 7 7 6 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 OAI98883.1 - 3.9e-05 23.9 0.2 23 5.4 0.0 7.9 8 2 2 10 10 9 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 OAI98883.1 - 0.0013 18.6 1.1 1.5 8.7 0.0 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) Pex16 PF08610.5 OAI98883.1 - 0.0074 15.3 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) RIX1 PF08167.7 OAI98883.1 - 0.011 15.3 5.4 0.95 9.1 0.0 5.4 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 OAI98883.1 - 0.024 14.4 11.1 7.2 6.4 0.1 6.6 5 3 2 7 7 7 0 non-SMC mitotic condensation complex subunit 1 RPAP1_C PF08620.5 OAI98883.1 - 0.031 14.1 0.4 8.6 6.2 0.1 3.7 4 0 0 4 4 3 0 RPAP1-like, C-terminal RRN3 PF05327.6 OAI98883.1 - 0.84 7.6 4.7 0.72 7.8 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 OAI98883.1 - 7.3 6.1 14.3 2.4 7.7 3.3 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region Septin PF00735.13 OAI98884.1 - 6.8e-107 356.6 0.6 8.4e-107 356.3 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 OAI98884.1 - 8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAI98884.1 - 0.00014 21.7 3.8 0.025 14.3 0.0 2.9 2 1 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 OAI98884.1 - 0.00052 20.1 0.0 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAI98884.1 - 0.00061 19.0 0.3 0.0023 17.1 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 OAI98884.1 - 0.00078 18.9 0.1 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 OAI98884.1 - 0.001 19.0 1.0 0.031 14.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 OAI98884.1 - 0.001 19.5 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 OAI98884.1 - 0.0015 18.0 0.2 0.0033 16.9 0.1 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 OAI98884.1 - 0.0025 18.6 0.5 0.0025 18.6 0.3 2.6 1 1 1 2 2 2 1 AAA domain AIG1 PF04548.11 OAI98884.1 - 0.0033 16.5 0.0 0.0062 15.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_33 PF13671.1 OAI98884.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAI98884.1 - 0.0063 16.2 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 OAI98884.1 - 0.0074 15.1 0.1 0.018 13.8 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 OAI98884.1 - 0.021 15.1 0.2 0.057 13.7 0.0 1.9 2 1 0 2 2 2 0 ABC transporter Gasdermin PF04598.7 OAI98884.1 - 0.03 13.0 0.9 0.039 12.7 0.6 1.1 1 0 0 1 1 1 0 Gasdermin family Ras PF00071.17 OAI98884.1 - 0.059 12.7 0.7 0.4 10.0 0.0 2.4 3 0 0 3 3 3 0 Ras family cobW PF02492.14 OAI98884.1 - 0.062 12.7 0.0 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 OAI98884.1 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 OAI98884.1 - 0.086 12.3 0.3 1.1 8.7 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 OAI98884.1 - 0.1 12.1 0.2 0.33 10.4 0.0 1.9 3 0 0 3 3 1 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 OAI98884.1 - 0.1 12.3 0.2 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 OAI98884.1 - 0.11 12.0 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAI98884.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAI98884.1 - 0.15 12.3 4.0 0.14 12.4 0.3 2.7 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.12 OAI98884.1 - 0.63 9.8 5.5 0.66 9.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Atg14 PF10186.4 OAI98884.1 - 1.3 7.8 6.3 1.9 7.3 4.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HEAT PF02985.17 OAI98888.1 - 0.0031 17.4 0.2 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 HEAT repeat PIF1 PF05970.9 OAI98891.1 - 1.3e-29 103.3 0.0 5.7e-26 91.3 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAI98891.1 - 3.2e-10 39.9 0.0 1.3e-09 37.9 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 OAI98891.1 - 9.2e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAI98891.1 - 8.1e-06 24.9 0.0 1.5e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 OAI98891.1 - 3.3e-05 23.5 0.1 8.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAI98891.1 - 0.00011 22.2 0.3 0.00046 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 OAI98891.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAI98891.1 - 0.00043 21.0 0.1 0.0013 19.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAI98891.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 OAI98891.1 - 0.00088 18.9 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 OAI98891.1 - 0.0017 18.2 0.0 0.0049 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAI98891.1 - 0.0022 17.7 0.1 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAI98891.1 - 0.0024 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 OAI98891.1 - 0.003 17.7 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAI98891.1 - 0.0042 16.6 0.1 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAI98891.1 - 0.0065 16.0 0.1 0.05 13.1 0.1 2.4 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 OAI98891.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 OAI98891.1 - 0.0091 16.0 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.10 OAI98891.1 - 0.015 14.0 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 OAI98891.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 OAI98891.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 OAI98891.1 - 0.018 14.5 0.1 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 OAI98891.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.4 OAI98891.1 - 0.027 13.4 0.1 0.073 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 OAI98891.1 - 0.042 13.5 0.1 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.6 OAI98891.1 - 0.055 12.1 0.1 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain cobW PF02492.14 OAI98891.1 - 0.056 12.8 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 OAI98891.1 - 0.084 12.0 0.1 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAI98891.1 - 0.093 11.8 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UvrD-helicase PF00580.16 OAI98891.1 - 0.098 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SRPRB PF09439.5 OAI98891.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 OAI98891.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 OAI98891.1 - 0.12 11.3 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Miro PF08477.8 OAI98891.1 - 0.13 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 OAI98891.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain GCR1_C PF12550.3 OAI98900.1 - 1e-05 25.2 0.4 2.4e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.15 OAI98900.1 - 0.057 13.3 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.1 OAI98900.1 - 0.17 11.8 0.6 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain FHA PF00498.21 OAI98901.1 - 2.6e-08 33.8 0.1 7.6e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 FHA domain PIF1 PF05970.9 OAI98906.1 - 8.7e-21 74.2 0.0 1.6e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI98906.1 - 1.9e-12 47.2 2.5 1.2e-11 44.5 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAI98906.1 - 1e-07 31.6 1.6 2.1e-07 30.5 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain Helitron_like_N PF14214.1 OAI98906.1 - 1.1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAI98906.1 - 0.0054 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 OAI98906.1 - 0.022 14.3 0.1 0.17 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 OAI98906.1 - 0.029 14.2 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 Torsin HTH_28 PF13518.1 OAI98910.1 - 0.07 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Baculo_PEP_C PF04513.7 OAI98911.1 - 0.028 14.2 1.2 0.2 11.4 0.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2959 PF11172.3 OAI98911.1 - 0.066 12.9 0.1 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) Mod_r PF07200.8 OAI98911.1 - 0.068 13.0 0.4 0.12 12.2 0.3 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Dynamin_M PF01031.15 OAI98911.1 - 0.13 10.9 0.4 0.78 8.4 0.3 1.8 1 1 1 2 2 2 0 Dynamin central region Lectin_N PF03954.9 OAI98911.1 - 0.22 10.8 3.7 0.16 11.4 0.7 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain AT_hook PF02178.14 OAI98912.1 - 0.71 9.7 8.0 2.4 8.1 5.5 2.0 1 0 0 1 1 1 0 AT hook motif DUF605 PF04652.11 OAI98914.1 - 0.1 11.9 17.4 0.1 11.9 12.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF1875 PF08961.5 OAI98914.1 - 7.7 5.7 11.5 2.8 7.1 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) OB_RNB PF08206.6 OAI98918.1 - 0.085 12.3 0.3 0.14 11.6 0.2 1.5 1 1 0 1 1 1 0 Ribonuclease B OB domain Transposase_21 PF02992.9 OAI98919.1 - 9.6e-22 77.1 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAI98919.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Histone PF00125.19 OAI98921.1 - 7.7e-28 96.4 0.9 1.2e-27 95.8 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI98921.1 - 8.5e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI98921.1 - 0.014 15.4 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Defensin_beta PF00711.14 OAI98922.1 - 0.24 11.3 2.3 0.32 10.9 0.3 2.1 2 0 0 2 2 2 0 Beta defensin NAD_binding_8 PF13450.1 OAI98924.1 - 3.3e-13 49.4 0.0 1.2e-12 47.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAI98924.1 - 0.00069 18.6 0.1 0.0026 16.7 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAI98924.1 - 0.067 12.2 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DUF3584 PF12128.3 OAI98925.1 - 0.0029 15.0 16.1 0.0078 13.6 4.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) IncA PF04156.9 OAI98925.1 - 0.0053 16.3 18.6 1.1 8.8 4.3 3.2 2 1 1 3 3 3 3 IncA protein FlxA PF14282.1 OAI98925.1 - 0.033 14.1 0.7 0.033 14.1 0.5 4.1 3 2 1 4 4 3 0 FlxA-like protein Mod_r PF07200.8 OAI98925.1 - 0.074 12.9 17.1 0.27 11.1 0.5 3.7 3 1 1 4 4 4 0 Modifier of rudimentary (Mod(r)) protein RNA_pol_Rpb4 PF03874.11 OAI98925.1 - 0.12 12.3 0.7 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 TBPIP PF07106.8 OAI98925.1 - 0.12 11.8 8.5 1.3 8.5 0.3 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TSC22 PF01166.13 OAI98925.1 - 0.15 12.0 8.0 0.58 10.1 0.2 3.8 3 1 2 5 5 5 0 TSC-22/dip/bun family DUF310 PF03750.8 OAI98925.1 - 0.17 12.0 3.8 0.32 11.1 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF310) Rootletin PF15035.1 OAI98925.1 - 0.2 11.6 19.7 0.2 11.5 1.2 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 OAI98925.1 - 0.28 11.0 16.3 0.58 10.0 1.6 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 OAI98925.1 - 0.29 11.5 10.2 5.1 7.4 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 OAI98925.1 - 0.32 11.4 1.9 0.86 10.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.4 OAI98925.1 - 0.62 10.2 7.5 1.6 8.8 0.4 3.3 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Striatin PF08232.7 OAI98925.1 - 0.88 9.8 15.6 0.45 10.8 0.9 3.8 2 1 1 3 3 3 0 Striatin family Macoilin PF09726.4 OAI98925.1 - 1.6 6.9 7.6 1.8 6.7 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein Mnd1 PF03962.10 OAI98925.1 - 1.8 8.2 14.3 0.13 11.9 0.6 3.1 2 1 1 3 3 3 0 Mnd1 family FliJ PF02050.11 OAI98925.1 - 1.8 8.6 10.6 0.12 12.4 0.3 3.1 2 2 1 3 3 3 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 OAI98925.1 - 3.7 7.3 16.5 13 5.5 1.1 4.4 3 1 0 3 3 3 0 Prefoldin subunit SlyX PF04102.7 OAI98925.1 - 4.5 7.7 13.3 3.7 7.9 1.1 4.2 3 1 1 4 4 4 0 SlyX ADIP PF11559.3 OAI98925.1 - 7.3 6.4 20.6 3.9 7.3 0.9 3.4 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 OAI98925.1 - 8.2 5.2 14.5 0.57 9.0 0.2 2.7 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ERM PF00769.14 OAI98925.1 - 8.3 5.8 18.7 0.17 11.4 1.6 3.1 3 0 0 3 3 3 0 Ezrin/radixin/moesin family PIF1 PF05970.9 OAI98929.1 - 4.7e-27 94.8 0.0 3.6e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 OAI98929.1 - 2e-09 37.2 0.0 1.5e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAI98929.1 - 3.3e-05 23.5 0.7 0.019 14.6 0.2 3.3 3 0 0 3 3 3 1 Part of AAA domain UvrD_C_2 PF13538.1 OAI98929.1 - 0.00084 19.4 0.1 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 OAI98929.1 - 0.0061 14.3 0.0 0.0096 13.7 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_11 PF13086.1 OAI98929.1 - 0.047 13.2 0.2 1.6 8.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 OAI98929.1 - 0.094 12.8 0.0 1 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain JmjC PF02373.17 OAI98930.1 - 0.00031 20.9 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Peptidase_C48 PF02902.14 OAI98931.1 - 2e-17 63.5 0.0 5.3e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3963 PF13124.1 OAI98931.1 - 0.3 10.9 1.1 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) zf-C2H2 PF00096.21 OAI98932.1 - 0.00032 20.8 4.9 0.31 11.4 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 OAI98932.1 - 0.0017 18.1 2.3 1.2 9.0 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAI98932.1 - 0.23 11.8 4.4 10 6.6 0.8 3.2 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 OAI98932.1 - 0.27 11.3 2.9 3.9 7.6 1.8 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 OAI98932.1 - 0.29 11.5 6.5 3.6 8.1 1.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2248 PF10005.4 OAI98933.1 - 0.095 11.6 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) GRAM PF02893.15 OAI98938.1 - 3.2e-19 68.2 0.0 2.1e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Toxin_29 PF08116.6 OAI98939.1 - 0.00039 20.1 1.6 0.00039 20.1 1.1 12.8 11 4 3 14 14 14 2 PhTx neurotoxin family Toxin_21 PF08091.6 OAI98939.1 - 0.11 12.1 0.2 0.11 12.1 0.1 12.0 7 4 4 11 11 11 0 Spider insecticidal peptide Thaumatin PF00314.12 OAI98940.1 - 1.1e-18 67.4 4.4 2.6e-18 66.2 3.0 1.6 1 1 0 1 1 1 1 Thaumatin family DUF4601 PF15373.1 OAI98941.1 - 0.081 11.7 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) PKD_channel PF08016.7 OAI98942.1 - 3.2e-06 25.8 14.6 1.3e-05 23.8 8.5 2.6 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 OAI98942.1 - 3.6e-06 26.3 8.0 0.00018 20.7 5.5 2.4 1 1 0 1 1 1 1 Ion transport protein DUF4601 PF15373.1 OAI98943.1 - 0.081 11.7 0.1 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) EMP24_GP25L PF01105.19 OAI98944.1 - 2e-21 76.5 0.1 2.8e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Lipase_3 PF01764.20 OAI98948.1 - 2.6e-07 30.3 0.0 2.3e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) RNase_H PF00075.19 OAI98949.1 - 1.3e-05 25.5 0.0 2.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNase H DnaJ-X PF14308.1 OAI98950.1 - 3.6e-46 157.0 0.6 8.7e-46 155.7 0.4 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 OAI98950.1 - 4.2e-26 90.4 1.1 1.2e-25 88.9 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2273 PF10031.4 OAI98951.1 - 0.0048 16.4 2.7 0.0095 15.5 1.9 1.4 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) DUF3357 PF11837.3 OAI98951.1 - 0.25 11.1 3.9 13 5.6 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3357) Pkinase PF00069.20 OAI98956.1 - 2.8e-12 46.3 0.0 3.2e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98956.1 - 6.9e-10 38.4 0.0 8.1e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Tme5_EGF_like PF09064.5 OAI98957.1 - 0.13 11.9 2.3 0.3 10.7 1.6 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like MULE PF10551.4 OAI98958.1 - 5e-15 55.4 0.0 3.8e-14 52.6 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAI98958.1 - 6.9e-10 38.0 0.2 2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.1 OAI98958.1 - 4.2e-05 23.5 0.2 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 1 DDE domain SWIM PF04434.12 OAI98958.1 - 8.7e-05 21.9 0.3 0.00019 20.8 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger SURF6 PF04935.7 OAI98963.1 - 1.5e-33 115.9 37.5 1.5e-33 115.9 26.0 3.6 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 OAI98963.1 - 3.6e-10 39.7 11.2 3.6e-10 39.7 7.8 5.7 3 2 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 DUF2457 PF10446.4 OAI98963.1 - 0.0038 16.0 31.3 0.0038 16.0 21.7 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Ceramidase_alk PF04734.8 OAI98964.1 - 2.4e-207 689.9 0.0 1.2e-205 684.3 0.0 2.3 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Myosin_tail_1 PF01576.14 OAI98965.1 - 1.2e-15 56.4 318.5 0.0011 16.7 39.9 11.2 1 1 8 10 10 10 8 Myosin tail Tropomyosin PF00261.15 OAI98965.1 - 3.8e-05 22.8 29.1 3.8e-05 22.8 20.1 11.8 1 1 10 11 11 11 4 Tropomyosin Tropomyosin_1 PF12718.2 OAI98965.1 - 7.9e-05 22.5 13.6 7.9e-05 22.5 9.4 15.5 1 1 14 15 15 15 3 Tropomyosin like IncA PF04156.9 OAI98965.1 - 0.00019 21.1 285.0 0.0025 17.4 16.6 15.6 1 1 14 15 15 15 6 IncA protein CENP-F_leu_zip PF10473.4 OAI98965.1 - 0.0003 20.6 15.8 0.0003 20.6 10.9 15.7 1 1 13 15 15 15 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 OAI98965.1 - 0.0017 17.0 18.8 0.0017 17.0 13.0 14.5 1 1 15 17 17 17 5 Spc7 kinetochore protein Reo_sigmaC PF04582.7 OAI98965.1 - 0.0027 16.9 17.3 0.0027 16.9 12.0 11.0 1 1 9 13 13 13 5 Reovirus sigma C capsid protein EcsC PF12787.2 OAI98967.1 - 0.092 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 EcsC protein family NUDIX PF00293.23 OAI98968.1 - 1e-06 28.4 0.1 1.7e-05 24.4 0.0 2.4 2 1 0 2 2 2 1 NUDIX domain Piwi PF02171.12 OAI98972.1 - 1.6e-77 260.4 0.0 2.4e-77 259.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAI98972.1 - 1.4e-15 56.7 0.0 2.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 OAI98972.1 - 1.1e-14 53.4 0.0 2.7e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Pkinase PF00069.20 OAI98974.1 - 9.5e-44 149.4 0.0 1.5e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI98974.1 - 6.4e-20 71.3 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF848 PF05852.6 OAI98974.1 - 0.004 17.0 0.2 0.0077 16.0 0.1 1.4 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) DUF4618 PF15397.1 OAI98974.1 - 0.033 13.5 0.6 0.054 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) FUSC PF04632.7 OAI98974.1 - 0.2 10.0 0.9 0.29 9.5 0.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin_2 PF01920.15 OAI98974.1 - 0.33 10.7 2.5 0.69 9.7 1.8 1.4 1 0 0 1 1 1 0 Prefoldin subunit Ferrochelatase PF00762.14 OAI98975.1 - 7.2e-105 350.4 0.0 8.7e-105 350.1 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 OAI98975.1 - 0.0088 16.1 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 2 CbiX WD40 PF00400.27 OAI98976.1 - 5.9e-19 67.1 4.5 1.2e-07 31.3 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 OAI98976.1 - 0.0085 16.0 1.0 0.0085 16.0 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 OAI98976.1 - 0.075 12.7 0.0 16 5.1 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 OAI98976.1 - 0.12 12.1 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Bromodomain PF00439.20 OAI98977.1 - 1.1e-20 73.3 0.0 2.1e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain EF-hand_7 PF13499.1 OAI98980.1 - 3.4e-07 30.3 0.3 6.5e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAI98980.1 - 7e-05 21.8 0.1 0.00027 20.0 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAI98980.1 - 0.00033 20.2 0.3 0.0015 18.2 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAI98980.1 - 0.0041 16.3 0.4 0.0083 15.4 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 OAI98980.1 - 0.04 13.5 2.0 0.13 11.8 0.1 2.5 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.4 OAI98980.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region 4HBT_2 PF13279.1 OAI98981.1 - 6.4e-07 29.8 0.0 8.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 OAI98981.1 - 5.2e-06 26.4 0.0 9e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 OAI98981.1 - 0.0064 15.4 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase ADH_N PF08240.7 OAI98982.1 - 4.4e-25 87.5 2.2 7.1e-25 86.8 1.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAI98982.1 - 1.6e-08 34.1 0.0 0.00097 18.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAI98982.1 - 0.00093 19.3 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_N_assoc PF13823.1 OAI98982.1 - 0.0049 16.5 2.4 0.0053 16.3 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 OAI98982.1 - 0.0051 15.9 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAI98982.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IL32 PF15225.1 OAI98983.1 - 0.17 11.8 0.6 0.26 11.2 0.4 1.3 1 0 0 1 1 1 0 Interleukin 32 MRP-L47 PF06984.8 OAI98984.1 - 8e-15 54.5 0.7 1.7e-14 53.5 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF1221 PF06760.6 OAI98984.1 - 0.022 14.0 0.2 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Ribosomal_L29 PF00831.18 OAI98984.1 - 0.045 13.4 2.6 0.1 12.3 0.7 2.2 1 1 1 2 2 2 0 Ribosomal L29 protein Flagellin_C PF00700.16 OAI98984.1 - 0.068 13.3 1.7 0.39 10.8 0.2 2.1 1 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region CPSF_A PF03178.10 OAI98985.1 - 5.5e-80 268.8 0.0 2e-79 267.0 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 OAI98985.1 - 2.7e-68 230.3 0.0 3.9e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Proteasome PF00227.21 OAI98986.1 - 4.2e-51 172.9 0.7 7.8e-51 172.0 0.2 1.6 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.3 OAI98986.1 - 3.7e-06 26.0 0.2 8.9e-06 24.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DnaJ-X PF14308.1 OAI98987.1 - 6.2e-58 195.4 6.4 6.8e-58 195.3 0.0 2.5 3 0 0 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.26 OAI98987.1 - 7.9e-19 67.1 0.1 7.9e-19 67.1 0.0 2.5 4 0 0 4 4 4 1 DnaJ domain HAD_2 PF13419.1 OAI98990.1 - 7.5e-10 39.3 0.0 3.6e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ICMT PF04140.9 OAI98991.1 - 1.4e-13 50.8 2.6 2.2e-13 50.1 0.5 2.2 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAI98991.1 - 3.1e-08 33.6 3.1 2.1e-07 31.0 2.1 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase Nitroreductase PF00881.19 OAI98994.1 - 3.7e-11 43.1 0.0 4.5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YodL PF14191.1 OAI98994.1 - 0.059 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 YodL-like zf-MYND PF01753.13 OAI98995.1 - 2.3e-07 30.5 14.5 5.7e-07 29.3 10.0 1.7 1 0 0 1 1 1 1 MYND finger Glyco_hydro_17 PF00332.13 OAI98996.1 - 8.5e-09 34.8 0.4 7.9e-05 21.8 0.2 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 17 Exo_endo_phos_2 PF14529.1 OAI98999.1 - 2.4e-10 40.0 0.0 4.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAI98999.1 - 3e-07 30.6 0.1 4.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FHA PF00498.21 OAI99003.1 - 0.0014 18.6 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain DDE_1 PF03184.14 OAI99004.1 - 2.5e-35 121.6 0.3 6.4e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAI99004.1 - 5.5e-09 35.9 1.0 8.9e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease AAA_11 PF13086.1 OAI99004.1 - 0.056 13.0 3.4 0.11 12.0 2.3 1.5 1 0 0 1 1 1 0 AAA domain PV_NSP1 PF12433.3 OAI99004.1 - 0.19 11.7 0.3 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein 1 Ycf1 PF05758.7 OAI99004.1 - 0.47 8.1 7.5 0.65 7.6 5.2 1.1 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 OAI99004.1 - 1.4 8.7 7.7 3.6 7.4 5.4 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 OAI99004.1 - 2.7 7.1 8.7 5.9 5.9 6.1 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LMBR1 PF04791.11 OAI99004.1 - 3.4 6.1 4.0 4.9 5.6 2.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AvrRpt-cleavage PF05627.6 OAI99005.1 - 0.0019 17.1 0.1 0.004 16.1 0.1 1.4 1 0 0 1 1 1 1 Cleavage site for pathogenic type III effector avirulence factor Avr rve PF00665.21 OAI99006.1 - 1e-11 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Retrotrans_gag PF03732.12 OAI99008.1 - 0.0081 16.2 0.1 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein HSBP1 PF06825.7 OAI99008.1 - 0.1 12.1 1.2 0.18 11.3 0.8 1.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Asp_protease_2 PF13650.1 OAI99009.1 - 0.00017 22.0 0.0 0.0004 20.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAI99009.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 OAI99009.1 - 0.016 15.0 0.0 0.041 13.8 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI99009.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Thioredoxin PF00085.15 OAI99012.1 - 5.9e-25 86.9 0.1 5.1e-24 83.9 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin Apolipoprotein PF01442.13 OAI99012.1 - 2.5e-05 23.8 10.7 0.017 14.6 3.8 3.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Thioredoxin_2 PF13098.1 OAI99012.1 - 3.4e-05 24.0 3.4 6.7e-05 23.0 0.0 3.1 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAI99012.1 - 0.00023 21.1 0.0 0.00072 19.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 OAI99012.1 - 0.0042 16.7 0.1 0.0095 15.6 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 OAI99012.1 - 0.014 15.3 1.1 0.031 14.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_6 PF13848.1 OAI99012.1 - 0.08 12.7 0.0 0.94 9.2 0.0 2.5 1 1 1 2 2 2 0 Thioredoxin-like domain Ish1 PF10281.4 OAI99012.1 - 0.32 11.1 2.5 4.7 7.3 0.1 3.6 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein TPR_11 PF13414.1 OAI99014.1 - 3.8e-13 48.8 2.8 1.5e-07 30.9 0.5 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAI99014.1 - 2.9e-06 26.7 1.7 0.00075 19.2 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAI99014.1 - 1e-05 24.8 1.8 0.0021 17.5 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAI99014.1 - 0.015 15.0 0.1 0.068 12.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAI99014.1 - 0.039 13.8 0.2 0.039 13.8 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAI99014.1 - 0.057 13.3 0.1 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAI99014.1 - 0.079 13.6 2.8 0.48 11.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAI99014.1 - 9.2 7.0 10.4 0.9 10.3 0.1 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAI99015.1 - 4.2e-08 33.4 3.8 0.0029 17.8 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAI99015.1 - 9.8e-07 28.8 6.5 0.18 12.5 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAI99015.1 - 9.4e-06 25.7 2.5 0.0021 18.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI99015.1 - 1.3e-05 24.7 0.9 0.032 13.8 0.0 3.3 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 OAI99015.1 - 1.7e-05 24.3 0.6 0.0031 17.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAI99015.1 - 2.2e-05 25.0 5.3 0.013 16.1 0.0 4.0 3 2 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 OAI99015.1 - 5.2e-05 23.2 0.0 0.094 12.8 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 OAI99015.1 - 0.00011 22.1 0.8 0.012 15.5 0.0 3.0 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 OAI99015.1 - 0.0024 17.8 0.6 0.21 11.5 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAI99015.1 - 0.0043 16.7 0.2 1.5 8.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 OAI99015.1 - 0.0089 15.9 1.5 0.052 13.5 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ELYS PF13934.1 OAI99015.1 - 0.013 15.2 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Nuclear pore complex assembly TPR_1 PF00515.23 OAI99015.1 - 0.044 13.4 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAI99015.1 - 1.2 9.7 0.0 1.2 9.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 OAI99016.1 - 7.9e-28 96.7 12.2 9.3e-28 96.4 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 OAI99016.1 - 0.1 10.7 0.6 0.11 10.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sigma70_r1_1 PF03979.9 OAI99016.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Ribosomal_S19 PF00203.16 OAI99017.1 - 7.3e-32 108.8 0.2 1e-31 108.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 W2 PF02020.13 OAI99018.1 - 4.7e-10 39.2 0.0 4.7e-10 39.2 0.0 3.9 4 0 0 4 4 4 2 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 OAI99018.1 - 2.4e-09 36.2 1.8 0.00094 18.5 0.1 4.0 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAI99018.1 - 0.0013 18.1 5.0 0.65 9.6 0.6 3.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 OAI99018.1 - 0.012 15.6 0.1 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 OAI99018.1 - 0.15 10.5 0.1 0.25 9.8 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase GCV_T PF01571.16 OAI99019.1 - 6.2e-16 58.3 0.0 1.1e-14 54.3 0.0 2.1 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAI99019.1 - 0.00033 20.6 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain eIF2A PF08662.6 OAI99020.1 - 1.1e-41 142.6 0.7 4.4e-37 127.6 0.0 4.4 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 OAI99020.1 - 6.2e-06 25.7 0.1 1.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI99020.1 - 1.1e-05 25.2 0.1 3.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI99020.1 - 6.7e-05 22.6 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAI99020.1 - 0.0015 18.3 7.1 0.93 9.4 0.0 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DsbC_N PF10411.4 OAI99020.1 - 0.11 11.7 0.0 0.4 9.9 0.0 1.9 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus Sec6 PF06046.8 OAI99021.1 - 6.8e-141 470.1 0.0 9.5e-141 469.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 OAI99021.1 - 0.0013 17.5 2.0 0.0057 15.4 0.4 2.4 3 0 0 3 3 3 1 Vps53-like, N-terminal AMP-binding PF00501.23 OAI99025.1 - 1.6e-71 240.9 0.0 2.7e-48 164.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAI99025.1 - 7.6e-08 33.2 0.0 2.9e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.13 OAI99026.1 - 5.8e-43 146.9 0.0 8e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase AMP-binding PF00501.23 OAI99027.1 - 1.6e-71 240.9 0.0 2.7e-48 164.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 OAI99027.1 - 7.6e-08 33.2 0.0 2.9e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain tRNA-synt_2c PF01411.14 OAI99028.1 - 4.3e-211 701.9 0.0 6.6e-211 701.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 OAI99028.1 - 7.8e-17 60.8 0.2 1.9e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain cobW PF02492.14 OAI99029.1 - 2.9e-49 166.9 4.8 6.1e-36 123.5 0.3 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 OAI99029.1 - 1e-17 63.6 0.3 1e-12 47.5 0.0 2.7 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 OAI99029.1 - 0.0099 13.9 1.4 0.015 13.3 1.0 1.2 1 0 0 1 1 1 1 CDC45-like protein AAA_22 PF13401.1 OAI99029.1 - 0.023 14.8 1.9 0.15 12.2 0.2 2.7 1 1 1 2 2 2 0 AAA domain Paf1 PF03985.8 OAI99029.1 - 0.032 12.9 1.5 0.068 11.8 1.1 1.4 1 0 0 1 1 1 0 Paf1 AAA_29 PF13555.1 OAI99029.1 - 0.05 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nop14 PF04147.7 OAI99029.1 - 0.052 11.4 3.8 0.081 10.8 2.6 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_10 PF12846.2 OAI99029.1 - 0.058 12.8 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 OAI99029.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 OAI99029.1 - 0.25 10.1 1.1 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 OAI99029.1 - 0.31 11.3 2.9 0.64 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain RNA_pol_N PF01194.12 OAI99030.1 - 3.5e-28 97.3 0.3 4.2e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Pkinase PF00069.20 OAI99031.1 - 5.5e-55 186.3 0.0 6.8e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99031.1 - 9.2e-38 129.7 0.0 1.2e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99031.1 - 2.9e-07 29.7 0.0 8.4e-07 28.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAI99031.1 - 0.013 15.2 0.0 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family UDPGP PF01704.13 OAI99032.1 - 5.6e-43 147.0 0.0 7.8e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SET PF00856.23 OAI99035.1 - 1.8e-08 34.8 0.0 1.8e-08 34.8 0.0 3.2 3 1 0 3 3 3 1 SET domain TFIIA PF03153.8 OAI99035.1 - 0.0012 18.8 11.2 0.0012 18.8 7.7 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF1777 PF08648.7 OAI99036.1 - 1.6e-20 73.5 60.3 2.3e-15 56.7 41.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) Extensin_2 PF04554.8 OAI99036.1 - 4.7 7.1 14.1 71 3.3 0.0 2.5 2 1 0 2 2 2 0 Extensin-like region Pkinase PF00069.20 OAI99037.1 - 9e-61 205.2 0.0 1.1e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99037.1 - 6.4e-35 120.4 0.0 9.3e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99037.1 - 3.3e-06 26.2 0.0 6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAI99037.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAI99037.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAI99037.1 - 0.22 10.3 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DEC-1_C PF04626.8 OAI99037.1 - 0.34 11.0 3.8 1.5 9.0 2.6 2.1 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Zn_clus PF00172.13 OAI99038.1 - 0.00021 21.1 12.0 0.0004 20.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1708 PF08101.6 OAI99039.1 - 3.1e-23 82.2 1.7 2.3e-16 59.6 0.2 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAI99039.1 - 0.00019 21.0 0.0 0.001 18.7 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain Herpes_LMP1 PF05297.6 OAI99039.1 - 0.68 8.8 5.1 1.7 7.5 3.6 1.6 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Histone PF00125.19 OAI99043.1 - 1.2e-11 44.5 0.1 1.5e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAI99043.1 - 4e-05 23.5 0.0 5.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAI99043.1 - 0.00033 20.0 0.0 0.00038 19.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TAF PF02969.12 OAI99043.1 - 0.00042 20.2 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 OAI99043.1 - 0.0014 18.7 0.1 0.0019 18.3 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 OAI99043.1 - 0.0046 16.6 0.0 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 OAI99043.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF4095 PF13338.1 OAI99043.1 - 0.014 15.5 0.3 0.019 15.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) Pkinase PF00069.20 OAI99044.1 - 3.6e-44 150.8 0.0 6.8e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99044.1 - 9.2e-26 90.4 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cation_ATPase_N PF00690.21 OAI99044.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Kinase-like PF14531.1 OAI99044.1 - 0.0076 15.2 0.0 0.019 13.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAI99044.1 - 0.041 13.5 1.6 0.063 13.0 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tropomyosin PF00261.15 OAI99044.1 - 0.085 11.9 32.3 1.7 7.6 22.6 2.6 1 1 0 1 1 1 0 Tropomyosin APG6 PF04111.7 OAI99044.1 - 2 7.4 16.2 3.1 6.7 11.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Uds1 PF15456.1 OAI99044.1 - 4.7 7.2 23.1 0.9 9.5 9.7 2.5 1 1 2 3 3 3 0 Up-regulated During Septation PIF1 PF05970.9 OAI99046.1 - 6e-23 81.3 0.0 1.9e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAI99046.1 - 1.7e-11 44.1 0.1 7.6e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI99046.1 - 5.8e-08 32.3 0.1 3e-07 30.1 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAI99046.1 - 3e-07 30.3 0.2 9e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAI99046.1 - 0.0024 17.8 3.1 0.0093 15.9 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain Torsin PF06309.6 OAI99046.1 - 0.012 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Torsin UvrD_C_2 PF13538.1 OAI99046.1 - 0.08 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAI99046.1 - 0.13 12.3 0.0 0.47 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1318 PF07027.7 OAI99046.1 - 0.37 11.0 1.7 0.54 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Dimer_Tnp_hAT PF05699.9 OAI99047.1 - 1.8e-09 37.1 0.0 5.2e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAI99047.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger DUF4413 PF14372.1 OAI99047.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) APC_CDC26 PF10471.4 OAI99048.1 - 0.041 14.6 1.3 0.062 14.0 0.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF3824 PF12868.2 OAI99048.1 - 0.051 14.5 0.6 0.059 14.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) XRCC4 PF06632.7 OAI99048.1 - 0.057 12.2 1.0 0.065 12.0 0.7 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF755 PF05501.6 OAI99048.1 - 1.7 8.6 11.1 2.5 8.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Chorismate_bind PF00425.13 OAI99053.1 - 4.6e-88 294.8 0.1 5.9e-88 294.5 0.1 1.1 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 OAI99053.1 - 5.2e-25 88.0 0.0 3.1e-24 85.5 0.0 2.3 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Erg28 PF03694.8 OAI99055.1 - 1.5e-41 140.8 2.0 1.8e-41 140.5 1.4 1.1 1 0 0 1 1 1 1 Erg28 like protein S1FA PF04689.8 OAI99055.1 - 0.16 11.8 0.1 2.5 8.0 0.1 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA PRP21_like_P PF12230.3 OAI99056.1 - 1.5e-55 188.2 1.6 1.5e-55 188.2 1.1 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 OAI99056.1 - 5.8e-33 112.3 0.4 4e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 Surp module DUF1743 PF08489.6 OAI99057.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) zf-DHHC PF01529.15 OAI99058.1 - 8.9e-33 113.1 1.5 8.9e-33 113.1 1.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase FA_desaturase PF00487.19 OAI99058.1 - 3 7.1 7.2 0.74 9.2 0.1 2.3 2 1 0 2 2 2 0 Fatty acid desaturase Hydrolase PF00702.21 OAI99059.1 - 5.5e-23 82.5 0.0 6.8e-22 78.9 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAI99059.1 - 4.7e-20 71.6 0.0 9.5e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAI99059.1 - 1e-18 68.1 0.0 2.2e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAI99059.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAI99059.1 - 0.0024 17.5 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 OAI99059.1 - 0.022 14.0 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Dynamin_M PF01031.15 OAI99060.1 - 7.9e-104 346.5 0.0 1.6e-103 345.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAI99060.1 - 1.9e-55 187.2 0.1 6.1e-55 185.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 OAI99060.1 - 5.7e-29 99.8 5.3 5.7e-29 99.8 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAI99060.1 - 0.0024 17.8 0.6 0.016 15.1 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAI99060.1 - 0.068 13.6 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein DUF3825 PF12873.2 OAI99061.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) GCS PF03074.11 OAI99067.1 - 2.7e-150 500.5 0.0 1.1e-123 412.9 0.0 2.7 1 1 1 2 2 2 2 Glutamate-cysteine ligase RIO1 PF01163.17 OAI99068.1 - 8.5e-38 129.5 0.1 1e-25 90.2 0.0 2.5 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 OAI99068.1 - 1.6e-29 101.8 0.0 3.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 OAI99068.1 - 4.4e-07 29.8 1.3 0.00032 20.5 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 OAI99068.1 - 0.026 13.5 0.0 0.19 10.8 0.0 2.1 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_5 PF12695.2 OAI99069.1 - 1.1e-10 41.4 0.4 3.3e-10 39.9 0.3 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAI99069.1 - 1.5e-07 30.8 0.0 3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAI99069.1 - 5.7e-05 23.1 4.2 0.00073 19.4 2.9 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAI99069.1 - 0.12 11.2 0.1 1.9 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DUF3546 PF12066.3 OAI99070.1 - 0.06 13.3 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) zf-C3HC4_3 PF13920.1 OAI99072.1 - 4.3e-10 39.1 4.2 6.5e-10 38.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAI99072.1 - 1.2e-05 25.2 5.1 2.2e-05 24.3 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI99072.1 - 1.3e-05 24.7 3.8 2.2e-05 24.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99072.1 - 3.2e-05 23.6 5.2 5.6e-05 22.8 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAI99072.1 - 0.00064 19.3 3.7 0.0011 18.6 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAI99072.1 - 1 9.0 3.3 2.5 7.7 2.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain muHD PF10291.4 OAI99073.1 - 1.3e-38 132.6 0.0 2.1e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 OAI99073.1 - 8.7e-09 35.4 0.3 4.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Adap_comp_sub PF00928.16 OAI99073.1 - 1.3e-05 24.4 0.0 3e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family IFT57 PF10498.4 OAI99073.1 - 0.12 11.1 2.4 0.18 10.4 1.7 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 IncA PF04156.9 OAI99073.1 - 7.3 6.1 8.9 1.7 8.2 2.6 2.1 2 0 0 2 2 2 0 IncA protein Epimerase PF01370.16 OAI99074.1 - 6.3e-19 68.3 0.0 9.7e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAI99074.1 - 4.7e-13 48.4 0.0 1e-12 47.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAI99074.1 - 1.1e-11 44.1 0.1 1.7e-10 40.2 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 OAI99074.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding TcpF PF06340.6 OAI99074.1 - 0.0029 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F RmlD_sub_bind PF04321.12 OAI99074.1 - 0.0042 16.0 0.0 0.017 14.0 0.0 2.0 3 0 0 3 3 3 1 RmlD substrate binding domain KR PF08659.5 OAI99074.1 - 0.073 12.7 0.1 0.38 10.4 0.0 2.1 2 1 0 2 2 2 0 KR domain adh_short PF00106.20 OAI99074.1 - 0.085 12.7 0.6 0.6 10.0 0.1 2.4 2 1 0 2 2 2 0 short chain dehydrogenase Ank_2 PF12796.2 OAI99075.1 - 1.6e-21 76.4 0.1 5.9e-10 39.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAI99075.1 - 2.8e-21 75.4 0.8 3.5e-12 46.4 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAI99075.1 - 6.9e-18 64.2 0.6 2.1e-08 34.1 0.0 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 OAI99075.1 - 8.9e-18 63.1 0.0 3.1e-07 29.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAI99075.1 - 4.5e-16 57.3 0.5 0.00015 21.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat KilA-N PF04383.8 OAI99075.1 - 3.1e-06 26.7 0.2 4e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain DUF3123 PF11321.3 OAI99075.1 - 0.021 15.0 3.2 0.049 13.9 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) BTB PF00651.26 OAI99075.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ATG16 PF08614.6 OAI99077.1 - 0.00053 19.8 8.6 0.00068 19.5 6.0 1.4 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) BSD PF03909.12 OAI99077.1 - 0.06 13.0 0.4 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 BSD domain Med4 PF10018.4 OAI99077.1 - 0.1 12.0 7.7 0.12 11.7 4.0 2.1 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PFEMP PF03011.10 OAI99077.1 - 0.15 12.3 7.4 0.025 14.9 2.8 1.5 2 0 0 2 2 2 0 PFEMP DBL domain DUF4480 PF13715.1 OAI99079.1 - 0.078 13.0 0.0 9 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4480) DUF1365 PF07103.6 OAI99082.1 - 6.6e-22 77.7 0.0 1.2e-20 73.6 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1365) GST_N_3 PF13417.1 OAI99083.1 - 0.00011 22.3 0.0 0.00048 20.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAI99083.1 - 0.021 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3608 PF12257.3 OAI99084.1 - 2.6e-66 223.4 0.0 1.4e-44 152.1 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF3608) DEP PF00610.16 OAI99084.1 - 2.5e-18 65.5 0.4 2.7e-17 62.2 0.1 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Abhydrolase_6 PF12697.2 OAI99085.1 - 2.3e-07 30.9 0.8 3.2e-07 30.4 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99085.1 - 8.7e-07 28.7 0.1 2.3e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAI99085.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 OAI99085.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF221 PF02714.10 OAI99086.1 - 2.7e-99 332.1 17.9 4.4e-99 331.4 12.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAI99086.1 - 5e-37 126.8 1.1 5e-37 126.8 0.8 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAI99086.1 - 7.5e-20 71.2 2.4 1.2e-19 70.6 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 OAI99086.1 - 2e-10 40.3 0.0 5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein Rsbr_N PF08678.5 OAI99086.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Rsbr N terminal HLH PF00010.21 OAI99087.1 - 2.2e-16 59.2 0.1 5.5e-16 58.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.14 OAI99087.1 - 0.01 16.1 3.6 0.01 16.1 2.5 6.1 7 1 1 8 8 8 0 60s Acidic ribosomal protein NOA36 PF06524.7 OAI99087.1 - 8.9 5.4 5.8 18 4.4 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2244 PF10003.4 OAI99090.1 - 0.4 10.0 3.3 0.46 9.8 1.1 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) HNH_2 PF13391.1 OAI99091.1 - 1.5e-07 31.0 0.0 6e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 HNH endonuclease DUF1776 PF08643.5 OAI99092.1 - 0.0023 17.1 0.0 0.083 12.0 0.0 2.3 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) DUF3246 PF11596.3 OAI99092.1 - 0.0026 17.1 0.3 0.0026 17.1 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3246) DUF1776 PF08643.5 OAI99095.1 - 0.0046 16.1 0.0 0.22 10.6 0.0 2.3 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) YjcZ PF13990.1 OAI99099.1 - 0.04 13.0 0.1 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 YjcZ-like protein DUF961 PF06125.6 OAI99101.1 - 0.11 12.7 0.4 0.15 12.2 0.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF961) PIF1 PF05970.9 OAI99105.1 - 3.9e-21 75.4 0.1 9.8e-21 74.0 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAI99105.1 - 9.1e-12 44.9 0.1 3.4e-11 43.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI99105.1 - 6e-07 29.1 0.2 1.7e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAI99105.1 - 6.8e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAI99105.1 - 0.0002 21.4 0.4 0.0017 18.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.9 OAI99105.1 - 0.0044 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 OAI99105.1 - 0.026 14.6 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAI99105.1 - 0.036 14.2 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAI99105.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_11 PF13086.1 OAI99105.1 - 0.19 11.2 0.2 29 4.1 0.0 2.7 1 1 1 2 2 2 0 AAA domain Bunya_RdRp PF04196.7 OAI99105.1 - 0.79 7.6 0.1 1.2 7.1 0.1 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase AT_hook PF02178.14 OAI99107.1 - 1.2 9.0 8.0 2.8 7.9 5.5 1.7 1 0 0 1 1 1 0 AT hook motif Histone PF00125.19 OAI99108.1 - 1e-11 44.7 0.1 1.3e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAI99108.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 OAI99108.1 - 2.4e-05 24.1 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 OAI99108.1 - 0.00043 20.3 0.0 0.00049 20.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAI99108.1 - 0.00059 19.1 0.0 0.00066 19.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 OAI99108.1 - 0.01 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 OAI99108.1 - 0.03 14.0 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated DUF4095 PF13338.1 OAI99108.1 - 0.036 14.2 0.2 0.054 13.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) F-box PF00646.28 OAI99110.1 - 0.068 12.8 0.1 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 F-box domain DDE_1 PF03184.14 OAI99111.1 - 2.3e-56 190.3 0.0 4.7e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI99111.1 - 7.1e-10 38.5 1.2 7.1e-10 38.5 0.8 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 OAI99111.1 - 4.9e-05 23.1 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAI99111.1 - 0.019 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Transposase HTH_32 PF13565.1 OAI99111.1 - 0.022 15.5 1.3 0.077 13.7 0.0 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Arg_repressor PF01316.16 OAI99111.1 - 0.049 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Phage_int_SAM_1 PF02899.12 OAI99112.1 - 0.045 13.9 0.2 0.083 13.0 0.0 1.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF883 PF05957.8 OAI99113.1 - 0.077 13.3 0.6 0.15 12.5 0.3 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.9 OAI99113.1 - 0.081 12.5 1.0 0.1 12.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4208 PF13907.1 OAI99113.1 - 0.15 12.2 1.0 0.23 11.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DUF1664 PF07889.7 OAI99113.1 - 0.16 11.8 1.1 0.23 11.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_integrase PF00589.17 OAI99117.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Tom37_C PF11801.3 OAI99118.1 - 2.4 8.0 4.5 4.2 7.2 3.2 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain RRM_1 PF00076.17 OAI99119.1 - 6.4e-11 41.7 0.0 9e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI99119.1 - 8.1e-10 38.5 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI99119.1 - 2.5e-05 24.0 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 OAI99123.1 - 3.3e-14 52.1 12.6 1e-07 31.5 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat CRAL_TRIO PF00650.15 OAI99124.1 - 6.6e-12 45.1 0.0 4.7e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Peptidase_M43 PF05572.8 OAI99125.1 - 1.8e-09 37.3 0.0 4.8e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A SDA1 PF05285.7 OAI99127.1 - 0.0086 15.4 22.6 0.012 14.9 15.7 1.1 1 0 0 1 1 1 1 SDA1 DUF2457 PF10446.4 OAI99127.1 - 0.031 13.0 36.5 0.065 11.9 25.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 OAI99127.1 - 0.28 9.6 26.4 0.46 8.9 18.3 1.3 1 0 0 1 1 1 0 Daxx Family Oxidored_FMN PF00724.15 OAI99128.1 - 3.6e-56 190.6 0.0 8.5e-53 179.5 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 OAI99129.1 - 5.4e-39 133.8 23.3 5.4e-39 133.8 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily HLH PF00010.21 OAI99130.1 - 2.2e-08 33.6 0.6 4.1e-08 32.7 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.8 OAI99130.1 - 0.0027 17.6 1.4 0.0027 17.6 1.0 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2423 PF10338.4 OAI99130.1 - 0.0099 15.8 0.3 0.027 14.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Nucleoplasmin PF03066.10 OAI99130.1 - 1.6 8.2 8.2 0.051 13.0 1.1 1.9 3 0 0 3 3 3 0 Nucleoplasmin DUF2457 PF10446.4 OAI99130.1 - 6.4 5.3 13.6 0.079 11.6 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Catalase PF00199.14 OAI99131.1 - 5.9e-175 581.5 1.9 7e-175 581.2 1.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAI99131.1 - 2.6e-19 68.8 0.0 7e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Tyrosinase PF00264.15 OAI99136.1 - 6.3e-11 42.8 0.5 6.4e-11 42.8 0.3 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase Macoilin PF09726.4 OAI99138.1 - 5.2 5.2 12.5 6 5.0 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Gemini_C4 PF01492.12 OAI99139.1 - 0.18 11.5 0.5 0.44 10.3 0.4 1.6 1 0 0 1 1 1 0 Geminivirus C4 protein TPR_12 PF13424.1 OAI99140.1 - 2e-07 30.8 6.4 0.00011 22.0 0.2 4.1 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAI99140.1 - 7.5e-05 22.5 7.0 0.019 14.8 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAI99140.1 - 0.02 14.7 0.1 34 4.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 OAI99144.1 - 4.5e-59 200.2 3.1 2.1e-27 95.7 0.2 4.0 2 2 1 3 3 3 3 Cytochrome P450 Ribosomal_L34 PF00468.12 OAI99145.1 - 1.3e-17 63.2 9.5 2.1e-17 62.4 6.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Rrn6 PF10214.4 OAI99145.1 - 0.073 11.1 8.3 0.083 10.9 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HRM PF02793.17 OAI99146.1 - 0.003 17.5 1.0 0.0056 16.6 0.7 1.5 1 0 0 1 1 1 1 Hormone receptor domain Histone PF00125.19 OAI99147.1 - 2.4e-30 104.4 0.4 3.7e-30 103.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI99147.1 - 4e-05 23.7 0.0 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI99147.1 - 0.028 14.4 0.1 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAI99147.1 - 0.055 12.7 0.8 0.085 12.0 0.6 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 OAI99147.1 - 0.087 12.5 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 OAI99148.1 - 4.6e-38 127.7 1.6 7.9e-09 35.0 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 OAI99148.1 - 4.9e-06 26.3 0.1 2.9e-05 23.8 0.1 2.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SNF2_N PF00176.18 OAI99149.1 - 1e-46 159.1 0.0 2e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAI99149.1 - 3.2e-11 42.9 0.0 7.6e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAI99149.1 - 0.00036 20.4 0.0 0.0045 16.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit EIF_2_alpha PF07541.7 OAI99150.1 - 3e-38 130.0 0.3 7.9e-38 128.6 0.2 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 OAI99150.1 - 2e-12 47.0 0.1 4.3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain AP_endonuc_2 PF01261.19 OAI99150.1 - 0.029 13.6 0.1 0.044 13.0 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EXOSC1 PF10447.4 OAI99150.1 - 0.042 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 GATA PF00320.22 OAI99156.1 - 0.0013 18.0 0.1 0.0013 18.0 0.0 2.1 2 0 0 2 2 2 1 GATA zinc finger JmjC PF02373.17 OAI99159.1 - 0.0031 17.7 0.1 0.0086 16.3 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Ferrochelatase PF00762.14 OAI99164.1 - 0.076 11.9 1.2 0.12 11.2 0.8 1.3 1 0 0 1 1 1 0 Ferrochelatase RAP1 PF07218.6 OAI99164.1 - 0.29 9.1 3.4 0.37 8.8 2.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S26e PF01283.14 OAI99164.1 - 0.7 10.1 4.5 18 5.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S26e TFIIA PF03153.8 OAI99164.1 - 2.2 8.0 9.4 3 7.6 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aldose_epim PF01263.15 OAI99167.1 - 3.9e-56 190.3 0.1 5.2e-56 189.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase NIF PF03031.13 OAI99169.1 - 2.4e-50 170.2 0.1 3.4e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_60s PF00428.14 OAI99169.1 - 0.0034 17.7 15.5 0.0034 17.7 10.7 6.4 3 1 0 3 3 3 1 60s Acidic ribosomal protein HAD_2 PF13419.1 OAI99169.1 - 0.14 12.4 0.1 1 9.5 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase BCIP PF13862.1 OAI99170.1 - 3.8e-32 111.3 0.0 6e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Spt5_N PF11942.3 OAI99170.1 - 0.024 15.2 8.2 1.2 9.7 1.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4129 PF13559.1 OAI99170.1 - 0.094 12.7 0.9 12 5.9 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) PBP1_TM PF14812.1 OAI99170.1 - 0.16 12.2 10.4 2.3 8.5 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 OAI99170.1 - 0.16 11.6 2.2 7.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFIIF_alpha PF05793.7 OAI99170.1 - 2.4 6.4 10.7 3.4 5.9 0.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Thiolase_N PF00108.18 OAI99171.1 - 1.5e-67 227.3 0.1 9.1e-67 224.8 0.1 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAI99171.1 - 3.2e-44 149.2 0.1 7.9e-44 148.0 0.1 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAI99171.1 - 2.1e-05 24.1 2.7 3e-05 23.6 0.1 2.5 2 1 2 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAI99171.1 - 0.014 15.0 0.2 0.95 9.1 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 OAI99171.1 - 0.053 13.5 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2428 PF10350.4 OAI99172.1 - 2.1e-44 151.4 0.0 5e-44 150.2 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) SQS_PSY PF00494.14 OAI99173.1 - 2.1e-43 148.5 1.3 2.6e-43 148.2 0.9 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase ORC2 PF04084.9 OAI99174.1 - 4.9e-37 127.4 0.0 2e-31 109.0 0.0 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 2 BSP_II PF05432.6 OAI99174.1 - 0.00038 19.8 2.9 0.00038 19.8 2.0 4.3 4 0 0 4 4 4 2 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 OAI99174.1 - 0.012 15.9 0.5 0.012 15.9 0.3 5.7 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 OAI99174.1 - 1.8 6.4 2.2 5.6 4.8 0.1 2.2 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 OAI99174.1 - 7.2 6.1 23.0 0.52 9.8 0.1 3.9 4 0 0 4 4 4 0 Nucleoplasmin Abhydrolase_2 PF02230.11 OAI99175.1 - 9.8e-60 201.6 0.0 1.3e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAI99175.1 - 1.5e-12 47.4 0.0 2.5e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI99175.1 - 8.1e-10 38.9 0.0 2e-09 37.6 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAI99175.1 - 0.0028 16.9 0.0 0.0089 15.2 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Cutinase PF01083.17 OAI99175.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.15 OAI99175.1 - 0.036 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAI99175.1 - 0.051 12.7 0.0 0.56 9.3 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 OAI99175.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 OAI99175.1 - 0.16 11.4 0.0 0.84 9.0 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) dCMP_cyt_deam_1 PF00383.17 OAI99176.1 - 1.7e-13 50.1 0.4 3e-13 49.2 0.3 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 OAI99176.1 - 2.1e-11 43.8 0.8 4.5e-10 39.5 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 OAI99176.1 - 1.1e-05 24.8 2.3 0.021 14.2 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases PIF1 PF05970.9 OAI99180.1 - 7.2e-21 74.5 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI99180.1 - 1.6e-13 50.7 0.7 3.9e-13 49.4 0.5 1.6 1 0 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAI99180.1 - 3.8e-07 30.0 0.0 1.4e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAI99180.1 - 1.3e-06 28.1 0.0 4.9e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAI99180.1 - 0.00076 19.5 0.1 0.004 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAI99180.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAI99180.1 - 0.019 14.8 0.0 0.096 12.5 0.0 2.1 2 0 0 2 2 2 0 Torsin UvrD_C_2 PF13538.1 OAI99180.1 - 0.094 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 OAI99180.1 - 0.12 12.0 0.3 0.77 9.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SF-assemblin PF06705.6 OAI99181.1 - 0.026 13.6 1.7 0.034 13.3 1.2 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Apolipoprotein PF01442.13 OAI99181.1 - 0.034 13.6 4.5 0.046 13.2 3.1 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FdhE PF04216.7 OAI99181.1 - 0.047 13.4 3.3 0.058 13.0 2.3 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation MULE PF10551.4 OAI99187.1 - 2.9e-09 36.9 0.0 6.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAI99187.1 - 0.0088 14.6 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIRM PF04433.12 OAI99189.1 - 1.1e-33 115.1 0.0 2.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 OAI99189.1 - 2.7e-08 33.1 0.8 4.6e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAI99189.1 - 2.7e-07 30.5 0.0 7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAI99189.1 - 9.8e-06 25.5 0.1 2.1e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2450 PF10475.4 OAI99189.1 - 0.5 9.2 0.9 0.89 8.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Glyco_hydro_45 PF02015.11 OAI99192.1 - 0.063 13.3 0.2 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Toxin_56 PF15534.1 OAI99193.1 - 0.086 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 56 zf-BED PF02892.10 OAI99193.1 - 0.15 11.8 2.7 0.36 10.6 1.9 1.6 1 1 0 1 1 1 0 BED zinc finger Pex2_Pex12 PF04757.9 OAI99195.1 - 6.7e-28 97.6 6.6 1.1e-27 96.9 4.5 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 OAI99195.1 - 3.1e-10 39.7 7.9 4.8e-10 39.0 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAI99195.1 - 2.7e-09 36.6 5.7 4e-09 36.0 4.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAI99195.1 - 3.8e-09 36.0 4.9 5.7e-09 35.5 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAI99195.1 - 2.4e-08 33.8 7.1 3.7e-08 33.2 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI99195.1 - 4.7e-07 29.3 6.1 7.4e-07 28.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAI99195.1 - 2.8e-06 26.9 1.6 5.1e-06 26.0 0.2 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAI99195.1 - 8.9e-06 25.7 3.8 1.5e-05 24.9 2.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 OAI99195.1 - 0.00064 19.5 2.9 0.00064 19.5 2.0 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 OAI99195.1 - 0.011 15.2 6.9 0.018 14.5 4.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 OAI99195.1 - 0.015 15.0 2.7 0.028 14.1 1.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 OAI99195.1 - 0.037 13.8 2.5 0.065 13.0 1.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 OAI99195.1 - 0.11 12.1 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) PAT1 PF09770.4 OAI99195.1 - 0.17 10.0 2.6 0.23 9.6 1.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IBR PF01485.16 OAI99195.1 - 0.21 11.4 3.8 0.46 10.3 2.7 1.6 1 0 0 1 1 1 0 IBR domain Prok-RING_4 PF14447.1 OAI99195.1 - 0.38 10.3 2.9 0.77 9.3 2.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF572 PF04502.8 OAI99195.1 - 0.66 9.1 5.8 1.1 8.4 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rtf2 PF04641.7 OAI99195.1 - 0.75 8.9 10.8 0.42 9.7 0.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF1049 PF06305.6 OAI99195.1 - 8.2 5.9 7.5 6.4 6.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Btz PF09405.5 OAI99196.1 - 0.00098 19.1 0.1 0.00098 19.1 0.1 4.6 4 1 0 4 4 4 2 CASC3/Barentsz eIF4AIII binding SDA1 PF05285.7 OAI99196.1 - 2.6 7.2 24.8 4.7 6.3 17.2 1.3 1 0 0 1 1 1 0 SDA1 zf-C3HC4 PF00097.20 OAI99197.1 - 7.1e-08 31.9 9.4 7.1e-08 31.9 6.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAI99197.1 - 1.8e-06 27.6 9.1 1.8e-06 27.6 6.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 OAI99197.1 - 1.9e-06 27.5 5.2 2e-06 27.5 2.4 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 OAI99197.1 - 5e-06 26.4 12.9 1.4e-05 25.0 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99197.1 - 6.1e-06 25.9 15.5 1.1e-05 25.0 7.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAI99197.1 - 1.9e-05 24.2 13.9 2.2e-05 24.1 6.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAI99197.1 - 2.4e-05 23.9 11.2 0.00019 21.0 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAI99197.1 - 3.8e-05 23.4 4.5 9e-05 22.2 1.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAI99197.1 - 0.00049 19.7 4.0 0.00049 19.7 2.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger SAP PF02037.22 OAI99197.1 - 0.0024 17.3 0.4 0.17 11.4 0.0 2.8 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 OAI99197.1 - 0.0052 16.2 5.1 0.0052 16.2 3.5 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C2HC_2 PF13913.1 OAI99197.1 - 0.0084 15.7 0.1 0.023 14.3 0.1 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-rbx1 PF12678.2 OAI99197.1 - 0.018 15.1 6.6 0.057 13.5 2.9 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger U-box PF04564.10 OAI99197.1 - 0.098 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 U-box domain zf-MIZ PF02891.15 OAI99197.1 - 0.32 10.5 11.0 1.8 8.1 5.8 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.16 OAI99197.1 - 0.44 10.4 8.5 13 5.8 0.0 2.7 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 OAI99197.1 - 1 9.2 6.3 1.9 8.3 2.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 OAI99197.1 - 1.3 8.6 10.9 2.7 7.6 5.8 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tropomyosin_1 PF12718.2 OAI99200.1 - 8.8e-44 148.8 27.6 1.1e-43 148.5 19.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 OAI99200.1 - 3.2e-12 46.0 27.3 4.8e-06 25.8 5.3 2.5 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 OAI99200.1 - 0.00012 21.9 25.7 0.11 12.3 0.9 3.8 1 1 3 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 OAI99200.1 - 0.0019 16.0 13.6 0.0019 16.0 9.4 2.0 1 1 1 2 2 2 1 Myosin tail Filament PF00038.16 OAI99200.1 - 0.0023 17.4 20.7 0.061 12.7 7.2 2.0 1 1 1 2 2 2 2 Intermediate filament protein DUF3450 PF11932.3 OAI99200.1 - 0.0024 17.2 15.9 0.032 13.5 5.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 OAI99200.1 - 0.0051 16.5 22.9 0.07 12.9 5.4 3.0 2 2 0 2 2 2 2 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 OAI99200.1 - 0.02 14.6 1.9 0.02 14.6 1.3 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ERM PF00769.14 OAI99200.1 - 0.041 13.4 26.5 0.31 10.5 11.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 OAI99200.1 - 0.045 12.2 11.5 0.06 11.8 8.0 1.2 1 0 0 1 1 1 0 AAA domain Striatin PF08232.7 OAI99200.1 - 0.048 13.9 18.6 0.18 12.1 3.4 2.2 1 1 1 2 2 2 0 Striatin family RasGAP_C PF03836.10 OAI99200.1 - 0.054 13.1 9.2 0.077 12.6 6.4 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Pox_A_type_inc PF04508.7 OAI99200.1 - 0.068 12.9 3.2 4.6 7.2 0.3 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FliD_C PF07195.7 OAI99200.1 - 0.072 12.3 11.2 0.63 9.2 0.3 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus HisKA_3 PF07730.8 OAI99200.1 - 0.1 12.9 11.9 1.3 9.4 1.7 4.0 1 1 2 3 3 3 0 Histidine kinase LRS4 PF10422.4 OAI99200.1 - 0.11 11.7 9.7 0.16 11.3 6.7 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 IncA PF04156.9 OAI99200.1 - 0.15 11.5 21.3 0.11 12.1 8.9 2.0 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 OAI99200.1 - 0.16 9.3 21.9 0.25 8.6 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Hsk3 PF08227.6 OAI99200.1 - 0.17 12.0 2.6 4.5 7.5 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Cep57_CLD PF14073.1 OAI99200.1 - 0.17 11.6 17.8 0.23 11.2 2.6 2.4 1 1 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF919 PF06034.6 OAI99200.1 - 0.24 11.0 6.1 3.4 7.3 0.3 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) V_ATPase_I PF01496.14 OAI99200.1 - 0.39 8.5 11.3 0.47 8.2 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uds1 PF15456.1 OAI99200.1 - 0.39 10.6 21.6 2.1 8.3 6.3 2.3 1 1 1 2 2 2 0 Up-regulated During Septation ATG16 PF08614.6 OAI99200.1 - 0.46 10.2 20.9 0.053 13.3 4.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 OAI99200.1 - 0.47 9.4 25.1 2.1 7.3 9.8 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 OAI99200.1 - 0.49 10.5 10.8 0.19 11.9 0.5 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 OAI99200.1 - 0.5 10.3 24.2 0.75 9.7 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 OAI99200.1 - 0.53 10.0 24.0 2.2 8.0 14.2 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein THOC7 PF05615.8 OAI99200.1 - 0.59 10.3 17.6 15 5.8 10.9 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 ADIP PF11559.3 OAI99200.1 - 0.68 9.8 22.5 5.8 6.7 3.6 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 OAI99200.1 - 0.72 8.9 2.6 2.4 7.2 1.4 1.7 1 1 0 1 1 1 0 Reovirus sigma C capsid protein SlyX PF04102.7 OAI99200.1 - 0.96 9.8 11.4 1.2 9.5 1.2 3.0 1 1 2 3 3 3 0 SlyX Laminin_II PF06009.7 OAI99200.1 - 1 9.1 10.7 4.7 6.9 2.5 2.5 1 1 1 2 2 2 0 Laminin Domain II FliJ PF02050.11 OAI99200.1 - 1 9.4 20.7 2.5 8.1 2.3 3.0 1 1 1 2 2 2 0 Flagellar FliJ protein Prefoldin_2 PF01920.15 OAI99200.1 - 1.2 8.9 20.8 1.4 8.7 1.5 3.5 1 1 3 4 4 4 0 Prefoldin subunit DUF3435 PF11917.3 OAI99200.1 - 1.2 7.7 10.3 1.6 7.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FlxA PF14282.1 OAI99200.1 - 1.3 9.0 10.3 8.6 6.3 7.0 2.4 1 1 0 1 1 1 0 FlxA-like protein GAS PF13851.1 OAI99200.1 - 1.3 8.1 20.5 36 3.4 14.2 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 OAI99200.1 - 1.5 8.9 9.6 7.5 6.6 0.4 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 OAI99200.1 - 1.5 8.8 7.7 2.9 7.9 1.4 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF4407 PF14362.1 OAI99200.1 - 1.8 7.4 18.4 5.4 5.8 12.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.13 OAI99200.1 - 2.2 7.8 13.3 1.1 8.8 3.7 2.3 1 1 0 2 2 2 0 Outer membrane efflux protein Spc7 PF08317.6 OAI99200.1 - 2.2 6.8 19.6 1.7 7.2 3.3 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.8 OAI99200.1 - 2.3 7.7 17.0 1.9 8.0 2.1 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HR1 PF02185.11 OAI99200.1 - 3.1 7.6 17.5 13 5.5 5.0 3.8 1 1 2 3 3 3 0 Hr1 repeat DUF4140 PF13600.1 OAI99200.1 - 4.1 7.9 20.1 1.8 9.0 2.5 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF812 PF05667.6 OAI99200.1 - 4.5 5.6 18.0 5.8 5.3 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Occludin_ELL PF07303.8 OAI99200.1 - 5.2 7.8 13.4 4.2 8.1 0.5 3.4 1 1 3 4 4 4 0 Occludin homology domain Osmo_CC PF08946.5 OAI99200.1 - 5.3 7.1 9.3 13 5.9 0.1 3.5 2 2 1 3 3 3 0 Osmosensory transporter coiled coil DUF972 PF06156.8 OAI99200.1 - 6.7 7.1 17.0 8.2 6.8 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Kinetocho_Slk19 PF12709.2 OAI99200.1 - 7.2 6.7 17.5 6.6 6.8 1.1 3.5 2 2 1 3 3 3 0 Central kinetochore-associated DUF1664 PF07889.7 OAI99200.1 - 9 6.1 9.3 18 5.1 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LETM1 PF07766.8 OAI99201.1 - 4.2e-17 62.0 0.1 1.9e-07 30.4 0.1 2.2 1 1 0 2 2 2 2 LETM1-like protein Acyl_transf_1 PF00698.16 OAI99203.1 - 8.7e-61 205.9 0.0 1.9e-58 198.3 0.0 3.5 3 1 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 OAI99203.1 - 4.1e-31 106.5 0.3 1e-30 105.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 OAI99203.1 - 1.4e-28 98.6 0.0 4.4e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain adh_short_C2 PF13561.1 OAI99203.1 - 2.8e-11 43.6 0.0 1.1e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAI99203.1 - 1.3e-08 34.9 1.3 1.3e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAI99203.1 - 3.6e-05 23.5 1.0 0.0013 18.4 0.0 2.7 2 1 0 2 2 2 1 KR domain GST_C_2 PF13410.1 OAI99206.1 - 8.2e-09 35.2 0.1 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAI99206.1 - 2.4e-08 34.0 0.0 5.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAI99206.1 - 3.1e-05 23.8 0.0 5.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAI99206.1 - 0.00084 19.7 0.0 0.0015 18.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAI99206.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 OAI99208.1 - 2.6e-60 203.7 0.0 2e-58 197.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99208.1 - 6.5e-27 94.2 0.0 7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99208.1 - 1.3e-05 24.3 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAI99208.1 - 0.063 12.9 2.5 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family PsbQ PF05757.6 OAI99208.1 - 1 8.7 6.4 2 7.7 4.4 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ABC_membrane PF00664.18 OAI99209.1 - 1.6e-41 142.5 41.8 8.5e-29 100.8 10.0 4.1 4 1 1 5 5 5 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAI99209.1 - 7.8e-29 100.7 0.0 3e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 OAI99209.1 - 2.7e-05 24.5 0.4 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAI99209.1 - 0.001 18.4 0.1 0.47 9.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 OAI99209.1 - 0.0027 17.8 0.1 4.8 7.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAI99209.1 - 0.0033 16.9 1.0 1 8.9 0.4 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 OAI99209.1 - 0.0038 16.4 2.8 3.5 6.8 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 OAI99209.1 - 0.0048 17.0 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 OAI99209.1 - 0.012 15.1 0.2 3.4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain Miro PF08477.8 OAI99209.1 - 0.013 16.0 0.7 4.1 7.9 0.2 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 OAI99209.1 - 0.032 14.0 0.1 15 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAI99209.1 - 0.051 13.5 3.5 0.42 10.5 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 OAI99209.1 - 0.062 13.5 2.3 16 5.7 0.4 3.5 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 OAI99209.1 - 0.08 11.8 0.1 9.1 5.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 OAI99209.1 - 0.096 12.3 1.0 1.4 8.6 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAI99209.1 - 0.12 11.5 0.3 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAI99209.1 - 0.16 12.8 0.5 0.91 10.3 0.3 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAI99209.1 - 0.17 12.0 0.1 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 OAI99209.1 - 0.18 11.6 1.2 0.45 10.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 NACHT PF05729.7 OAI99209.1 - 0.43 10.2 2.8 6 6.5 0.3 2.6 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 OAI99209.1 - 0.96 8.8 4.3 5.9 6.3 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family cobW PF02492.14 OAI99209.1 - 3.1 7.2 4.5 1.4 8.2 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cation_efflux PF01545.16 OAI99212.1 - 4.5e-76 255.6 5.2 3.1e-75 252.8 3.6 1.9 1 1 0 1 1 1 1 Cation efflux family DUF883 PF05957.8 OAI99213.1 - 0.053 13.9 1.8 0.053 13.9 1.2 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_E PF05680.7 OAI99213.1 - 0.14 12.1 3.1 4.7 7.2 0.3 2.2 2 0 0 2 2 2 0 ATP synthase E chain DUF349 PF03993.7 OAI99213.1 - 6.8 6.9 14.8 0.12 12.5 0.7 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Ssu72 PF04722.8 OAI99214.1 - 3.3e-82 274.5 0.0 3.8e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 OAI99214.1 - 0.019 15.2 0.1 0.043 14.1 0.0 1.6 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase Virul_fac_BrkB PF03631.10 OAI99215.1 - 1.6e-06 27.6 2.5 3.9e-06 26.4 1.7 1.6 1 1 0 1 1 1 1 Virulence factor BrkB Dispanin PF04505.7 OAI99215.1 - 0.56 9.7 6.5 13 5.4 0.1 3.8 3 0 0 3 3 3 0 Interferon-induced transmembrane protein ADH_N PF08240.7 OAI99216.1 - 1.2e-31 108.6 0.2 2.2e-31 107.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAI99216.1 - 4e-27 94.3 0.2 6.1e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 OAI99216.1 - 0.00029 20.4 0.4 0.00075 19.1 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 OAI99216.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 OAI99216.1 - 0.0024 17.8 0.1 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 OAI99216.1 - 0.02 13.8 0.2 0.028 13.4 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Methyltransf_11 PF08241.7 OAI99216.1 - 0.03 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAI99216.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAI99216.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ceramidase PF05875.7 OAI99217.1 - 2e-65 220.5 5.0 2.3e-65 220.3 3.4 1.0 1 0 0 1 1 1 1 Ceramidase Mito_carr PF00153.22 OAI99218.1 - 1e-67 223.8 3.9 3.5e-22 77.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BTAD PF03704.12 OAI99218.1 - 0.11 12.7 0.4 0.18 12.1 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DASH_Dad4 PF08650.5 OAI99219.1 - 6.8e-19 67.5 0.0 9e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 OAI99219.1 - 0.0096 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 PRMT5 PF05185.11 OAI99220.1 - 4e-147 490.7 0.0 5e-147 490.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 OAI99220.1 - 0.0042 17.1 0.0 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain HMG_box PF00505.14 OAI99222.1 - 1.8e-15 56.9 1.7 2.4e-15 56.5 0.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAI99222.1 - 2e-11 44.0 0.3 4.4e-11 43.0 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain Gly-zipper_OmpA PF13436.1 OAI99222.1 - 6.7 6.4 22.5 4 7.1 3.3 3.6 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DAP3 PF10236.4 OAI99229.1 - 6.3e-40 137.0 0.0 1e-39 136.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 OAI99229.1 - 1.9e-05 24.7 1.4 4e-05 23.6 1.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 OAI99229.1 - 0.16 11.6 0.0 1.2 8.7 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase GTP1_OBG PF01018.17 OAI99230.1 - 1.9e-37 128.3 1.0 9.6e-27 93.5 0.9 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 OAI99230.1 - 2.7e-17 62.7 0.0 6.2e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAI99230.1 - 0.00035 19.8 0.1 0.00078 18.7 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAI99230.1 - 0.0095 15.3 0.0 2.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 OAI99230.1 - 0.058 12.1 0.8 1 8.0 0.1 2.3 2 0 0 2 2 2 0 ArgK protein Gtr1_RagA PF04670.7 OAI99230.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Oxidored-like PF09791.4 OAI99230.1 - 0.15 11.4 0.5 0.46 9.9 0.4 1.9 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal ABC_tran PF00005.22 OAI99230.1 - 0.17 12.1 0.9 0.41 10.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF3661 PF12400.3 OAI99231.1 - 3.2e-39 133.9 5.6 4.5e-39 133.5 3.9 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein PsbI PF02532.9 OAI99231.1 - 0.62 9.7 3.3 2 8.1 2.3 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MBOAT_2 PF13813.1 OAI99232.1 - 2.9e-05 24.0 1.7 0.0065 16.5 0.2 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family CAP PF00188.21 OAI99233.1 - 3.5e-22 79.2 2.4 5.6e-22 78.5 1.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family R3H PF01424.17 OAI99235.1 - 2.2e-13 49.6 0.1 8.7e-13 47.7 0.0 2.1 2 0 0 2 2 2 1 R3H domain Acyltransferase PF01553.16 OAI99240.1 - 5.7e-20 71.0 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase ELL PF10390.4 OAI99240.1 - 0.22 10.7 3.6 0.4 9.8 2.5 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Peroxin-3 PF04882.7 OAI99241.1 - 2.5e-93 313.1 0.0 1.5e-92 310.6 0.0 2.1 1 1 0 1 1 1 1 Peroxin-3 Fringe PF02434.11 OAI99242.1 - 5.7e-08 32.2 0.0 9.4e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Phospholip_A2_1 PF00068.14 OAI99242.1 - 0.0097 16.1 1.3 0.016 15.3 0.9 1.3 1 0 0 1 1 1 1 Phospholipase A2 Galactosyl_T PF01762.16 OAI99242.1 - 0.094 12.3 0.0 0.31 10.6 0.0 1.7 1 1 1 2 2 2 0 Galactosyltransferase FAD_binding_3 PF01494.14 OAI99243.1 - 1e-16 60.9 6.4 7.7e-08 31.7 0.2 3.3 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 OAI99243.1 - 0.0051 16.8 0.3 0.021 14.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAI99243.1 - 0.017 15.5 0.3 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAI99243.1 - 0.019 13.8 6.2 0.42 9.4 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein SE PF08491.5 OAI99243.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Whi5 PF08528.6 OAI99244.1 - 5.1e-09 35.4 0.0 8.1e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Whi5 like SOBP PF15279.1 OAI99244.1 - 0.13 12.6 41.0 0.014 15.7 12.9 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein Atrophin-1 PF03154.10 OAI99245.1 - 0.0044 15.2 9.7 0.0059 14.8 6.7 1.2 1 0 0 1 1 1 1 Atrophin-1 family VIT1 PF01988.14 OAI99245.1 - 0.02 14.3 0.5 0.022 14.2 0.4 1.2 1 0 0 1 1 1 0 VIT family DUF2217 PF10265.4 OAI99245.1 - 0.083 11.6 6.0 0.096 11.4 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2956 PF11169.3 OAI99245.1 - 0.19 11.7 9.0 0.84 9.6 6.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF4355 PF14265.1 OAI99245.1 - 0.23 11.4 13.8 0.33 10.9 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) HemX PF04375.9 OAI99245.1 - 0.3 9.6 9.6 0.4 9.2 6.7 1.1 1 0 0 1 1 1 0 HemX DUF2058 PF09831.4 OAI99245.1 - 1.1 9.1 11.3 1.4 8.7 7.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DNA_pol_viral_N PF00242.12 OAI99245.1 - 1.3 7.9 9.6 1.5 7.7 6.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SLD3 PF08639.5 OAI99245.1 - 1.4 7.4 9.8 1.7 7.1 6.8 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 OmpH PF03938.9 OAI99245.1 - 2 8.3 13.1 2.8 7.8 9.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 OAI99245.1 - 2.1 6.8 4.2 2.5 6.6 2.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.8 OAI99245.1 - 2.7 6.4 5.0 2.7 6.4 3.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gastrin PF00918.12 OAI99245.1 - 3.7 8.4 11.9 1 10.1 5.8 1.7 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Peptidase_S64 PF08192.6 OAI99245.1 - 3.8 5.7 6.1 4.6 5.4 4.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 SpoVR PF04293.8 OAI99245.1 - 4 5.6 7.6 5.2 5.3 5.3 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF1675 PF07897.6 OAI99245.1 - 4.8 6.9 11.1 6.8 6.4 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4407 PF14362.1 OAI99245.1 - 6.2 5.6 8.7 8.3 5.2 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGP_phosphatase PF09419.5 OAI99246.1 - 1.5e-39 135.0 0.0 1.4e-34 118.9 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 OAI99246.1 - 0.12 12.0 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 HAD-hyrolase-like SSP160 PF06933.6 OAI99247.1 - 0.46 8.4 6.3 0.42 8.5 4.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_MLP1_2 PF07926.7 OAI99252.1 - 5.4e-05 22.9 12.8 6.7e-05 22.6 8.9 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GAS PF13851.1 OAI99252.1 - 0.00062 19.0 10.0 0.00082 18.6 6.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 OAI99252.1 - 0.0044 16.5 14.3 0.016 14.6 9.7 1.8 1 1 0 1 1 1 1 Intermediate filament protein Gp58 PF07902.6 OAI99252.1 - 0.008 14.4 1.2 0.0093 14.2 0.8 1.1 1 0 0 1 1 1 1 gp58-like protein SCP-1 PF05483.7 OAI99252.1 - 0.011 13.5 8.2 0.013 13.2 5.7 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) bZIP_1 PF00170.16 OAI99252.1 - 0.023 14.6 10.0 0.044 13.7 0.1 2.9 2 1 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 OAI99252.1 - 0.027 14.3 15.7 0.077 12.8 2.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 OAI99252.1 - 0.031 14.5 0.8 1.5 9.1 0.0 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Gasdermin PF04598.7 OAI99252.1 - 0.031 13.0 1.4 0.042 12.5 1.0 1.1 1 0 0 1 1 1 0 Gasdermin family IFT57 PF10498.4 OAI99252.1 - 0.043 12.5 7.5 0.064 11.9 5.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 ADIP PF11559.3 OAI99252.1 - 0.062 13.1 13.0 0.72 9.7 0.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.1 OAI99252.1 - 0.076 12.3 5.4 0.095 12.0 3.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2968 PF11180.3 OAI99252.1 - 0.079 12.3 15.5 0.048 13.0 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 OAI99252.1 - 0.1 11.7 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DivIC PF04977.10 OAI99252.1 - 0.11 11.9 13.5 1.5 8.3 0.4 2.7 1 1 2 3 3 3 0 Septum formation initiator Tropomyosin_1 PF12718.2 OAI99252.1 - 0.12 12.2 21.0 0.48 10.2 14.0 2.0 1 1 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 OAI99252.1 - 0.13 12.6 10.4 0.44 10.9 3.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 OAI99252.1 - 0.15 12.2 2.8 0.33 11.0 1.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 OAI99252.1 - 0.16 11.9 16.9 0.13 12.2 7.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 OAI99252.1 - 0.29 10.8 16.3 2.2 8.0 5.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 OAI99252.1 - 0.36 9.2 8.0 0.46 8.8 5.5 1.1 1 0 0 1 1 1 0 AAA domain DUF904 PF06005.7 OAI99252.1 - 0.37 11.1 14.0 1.1 9.6 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 OAI99252.1 - 0.56 9.7 15.2 13 5.2 10.6 2.0 1 1 0 1 1 1 0 IncA protein DUF1640 PF07798.6 OAI99252.1 - 1.5 8.7 8.5 3.2 7.7 5.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Kinetocho_Slk19 PF12709.2 OAI99252.1 - 1.8 8.6 7.2 2 8.5 0.7 2.6 1 1 0 2 2 2 0 Central kinetochore-associated DUF4407 PF14362.1 OAI99252.1 - 2 7.3 12.8 2.5 7.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 OAI99252.1 - 2.1 8.1 8.4 4.1 7.1 0.9 3.1 2 2 1 3 3 3 0 Homeobox associated leucine zipper Z1 PF10593.4 OAI99252.1 - 3.2 6.8 7.4 2.4 7.2 0.1 2.0 1 1 1 2 2 2 0 Z1 domain Jnk-SapK_ap_N PF09744.4 OAI99252.1 - 4.7 7.1 11.3 6.8 6.6 7.6 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.6 OAI99252.1 - 5.6 5.5 13.3 4.8 5.7 0.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GrpE PF01025.14 OAI99252.1 - 8 5.9 16.7 6.7 6.2 4.7 2.1 1 1 0 2 2 2 0 GrpE DUF2570 PF10828.3 OAI99252.1 - 8.9 5.9 11.5 2.7 7.6 5.9 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2570) Mnd1 PF03962.10 OAI99252.1 - 9 5.9 14.1 1.9e+02 1.6 9.7 2.2 1 1 0 1 1 1 0 Mnd1 family FUSC PF04632.7 OAI99252.1 - 9.6 4.4 9.0 10 4.3 6.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIF1 PF05970.9 OAI99255.1 - 1.6e-20 73.4 0.0 3.4e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI99255.1 - 1.3e-11 44.4 0.0 5e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI99255.1 - 1.3e-06 28.0 1.8 2.2e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Helitron_like_N PF14214.1 OAI99255.1 - 1.5e-06 28.0 0.0 4.4e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAI99255.1 - 0.0063 16.5 0.0 0.028 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAI99255.1 - 0.036 14.2 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAI99255.1 - 0.16 12.1 0.0 0.52 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 OAI99255.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Bunya_RdRp PF04196.7 OAI99255.1 - 0.59 8.0 0.0 0.87 7.5 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase DUF3288 PF11691.3 OAI99256.1 - 0.019 14.6 0.4 0.034 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) ATP-synt_B PF00430.13 OAI99256.1 - 0.046 13.5 1.1 0.074 12.8 0.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Pacs-1 PF10254.4 OAI99256.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein AMOP PF03782.12 OAI99259.1 - 0.11 12.4 0.7 0.16 11.9 0.5 1.3 1 1 0 1 1 1 0 AMOP domain rve PF00665.21 OAI99263.1 - 1.1e-15 57.7 0.0 3.1e-15 56.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain rve PF00665.21 OAI99268.1 - 1.3e-13 51.1 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI99269.1 - 4.8e-17 62.0 0.0 8.9e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAI99269.1 - 0.00017 22.0 0.0 0.00045 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI99269.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI99269.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Ycf1 PF05758.7 OAI99274.1 - 2.8 5.5 6.7 3.8 5.1 4.7 1.2 1 0 0 1 1 1 0 Ycf1 tRNA-synt_2d PF01409.15 OAI99275.1 - 7.3e-87 290.6 0.0 1e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAI99275.1 - 4e-06 26.5 0.0 8.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 OAI99275.1 - 4.2e-05 22.4 1.0 0.0012 17.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) Cas_Cas2CT1978 PF09707.5 OAI99276.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2613 PF11021.3 OAI99277.1 - 0.064 12.9 1.7 0.17 11.5 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Fork_head PF00250.13 OAI99278.1 - 6.9e-22 77.2 0.0 1.4e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Fork head domain gerPA PF10676.4 OAI99278.1 - 7.9 6.3 8.2 0.21 11.4 0.6 2.3 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF RAP1 PF07218.6 OAI99278.1 - 9.6 4.1 4.7 22 2.9 3.3 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Asp PF00026.18 OAI99280.1 - 1.5e-08 34.2 0.0 2.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease GCV_T_C PF08669.6 OAI99281.1 - 0.006 16.5 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain RPT PF13446.1 OAI99282.1 - 0.35 10.3 3.0 1.6e+02 1.7 0.0 4.6 5 0 0 5 5 5 0 A repeated domain in UCH-protein Uricase PF01014.13 OAI99287.1 - 1.8e-55 186.7 0.0 1.1e-34 119.4 0.0 3.0 3 0 0 3 3 3 3 Uricase Arrestin_C PF02752.17 OAI99288.1 - 3.2e-14 53.2 0.0 9.6e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain HLH PF00010.21 OAI99289.1 - 3.4e-06 26.6 0.6 8.9e-06 25.3 0.4 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sigma70_ner PF04546.8 OAI99289.1 - 0.079 12.5 14.2 0.097 12.2 1.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 OAI99289.1 - 0.48 8.2 22.0 0.86 7.4 5.9 2.1 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.7 OAI99289.1 - 2.2 6.5 17.0 0.33 9.2 3.3 2.1 2 0 0 2 2 2 0 Mpp10 protein Nucleoplasmin PF03066.10 OAI99289.1 - 3.1 7.2 28.2 3.3 7.2 9.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin BCDHK_Adom3 PF10436.4 OAI99290.1 - 0.022 14.2 1.0 0.034 13.6 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Orbi_VP5 PF00901.12 OAI99290.1 - 0.2 9.8 14.2 0.27 9.3 9.9 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1129 PF06570.6 OAI99290.1 - 7 5.9 6.5 4.4 6.5 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Neur_chan_memb PF02932.11 OAI99290.1 - 7.1 6.4 11.5 12 5.6 8.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP11 PF06644.6 OAI99290.1 - 7.4 5.9 17.2 12 5.2 11.9 1.4 1 0 0 1 1 1 0 ATP11 protein DUF2317 PF10079.4 OAI99290.1 - 7.5 5.0 15.3 9.7 4.6 10.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) tRNA-synt_1g PF09334.6 OAI99291.1 - 3.6e-95 318.9 1.5 7.8e-92 307.9 1.0 3.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAI99291.1 - 1.5e-15 56.2 0.1 3.2e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 OAI99291.1 - 1.4e-07 31.0 0.1 0.0021 17.2 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MT0933_antitox PF14013.1 OAI99291.1 - 0.054 13.6 1.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 MT0933-like antitoxin protein RRM_1 PF00076.17 OAI99292.1 - 5.6e-24 83.5 0.0 1.8e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 OAI99292.1 - 1.7e-18 64.9 0.0 0.00018 20.8 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 OAI99292.1 - 3e-18 65.5 0.0 3.1e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI99292.1 - 1.8e-15 56.5 0.0 8.5e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 OAI99292.1 - 0.06 11.0 5.6 0.09 10.4 3.9 1.1 1 0 0 1 1 1 0 Ycf1 Nab6_mRNP_bdg PF10567.4 OAI99292.1 - 0.079 11.9 0.0 0.079 11.9 0.0 2.3 2 0 0 2 2 1 0 RNA-recognition motif zf-DHHC PF01529.15 OAI99292.1 - 0.18 11.2 0.2 0.43 9.9 0.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tim54 PF11711.3 OAI99292.1 - 0.46 9.0 10.0 1.2 7.6 7.0 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRTP PF01366.13 OAI99292.1 - 1.2 6.9 8.4 2.3 6.1 5.8 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein HTH_21 PF13276.1 OAI99292.1 - 1.8 8.6 2.6 0.85 9.6 0.0 1.7 2 0 0 2 2 1 0 HTH-like domain LMBR1 PF04791.11 OAI99292.1 - 3.5 6.1 1.6 6.1 5.3 1.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AUX_IAA PF02309.11 OAI99292.1 - 6.7 6.3 17.9 11 5.6 9.0 3.0 2 0 0 2 2 2 0 AUX/IAA family Baculo_PP31 PF05311.6 OAI99292.1 - 8 5.6 15.8 21 4.2 10.9 1.7 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RVT_1 PF00078.22 OAI99296.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Patatin PF01734.17 OAI99297.1 - 9.2e-05 22.4 0.8 0.00022 21.2 0.5 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Tyrosinase PF00264.15 OAI99298.1 - 7.4e-35 121.1 2.8 1.1e-34 120.5 1.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase PIRT PF15099.1 OAI99299.1 - 1.1 8.4 6.1 0.22 10.7 0.3 2.0 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family AATF-Che1 PF13339.1 OAI99299.1 - 2.2 8.4 5.7 0.63 10.1 1.3 1.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Calc_CGRP_IAPP PF00214.14 OAI99299.1 - 3.3 7.7 9.2 0.69 9.9 0.5 2.2 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family Phage_integrase PF00589.17 OAI99301.1 - 0.0071 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Adaptin_N PF01602.15 OAI99302.1 - 0.00014 20.3 0.0 0.00018 20.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region BUD22 PF09073.5 OAI99302.1 - 0.0021 17.2 0.7 0.0025 16.9 0.5 1.0 1 0 0 1 1 1 1 BUD22 eIF3_subunit PF08597.5 OAI99302.1 - 0.026 14.1 0.3 0.035 13.6 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tyrosinase PF00264.15 OAI99303.1 - 1.4e-32 113.6 1.1 3.4e-32 112.4 0.8 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Flavin_Reduct PF01613.13 OAI99304.1 - 7.3e-25 87.6 0.0 1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF1034 PF06280.7 OAI99307.1 - 8e-08 32.6 1.0 9.6e-08 32.4 0.7 1.1 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) RicinB_lectin_2 PF14200.1 OAI99307.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF1110 PF06533.7 OAI99312.1 - 0.0089 15.8 0.4 0.017 14.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1110) CDC45 PF02724.9 OAI99312.1 - 0.058 11.4 0.3 0.056 11.4 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S64 PF08192.6 OAI99312.1 - 0.28 9.4 1.5 0.37 9.0 1.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 SelP_N PF04592.9 OAI99312.1 - 7.7 5.8 12.0 12 5.2 8.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DPBB_1 PF03330.13 OAI99315.1 - 0.0043 17.0 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Abhydrolase_5 PF12695.2 OAI99316.1 - 8.2e-06 25.6 0.8 2.3e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI99316.1 - 0.00037 20.4 0.2 0.0014 18.6 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAI99316.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3402 PF11882.3 OAI99317.1 - 6.2e-133 443.7 0.0 3.1e-130 434.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.8 OAI99317.1 - 5.1e-42 143.7 0.0 2.5e-38 131.5 0.0 2.3 2 0 0 2 2 2 2 N1221-like protein Abhydrolase_6 PF12697.2 OAI99318.1 - 9.8e-06 25.6 0.5 2.2e-05 24.4 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99318.1 - 0.00058 19.6 0.4 0.0014 18.3 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAI99318.1 - 0.066 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LCAT PF02450.10 OAI99318.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Trypan_PARP PF05887.6 OAI99319.1 - 5.9 6.6 22.5 11 5.7 0.1 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DPBB_1 PF03330.13 OAI99320.1 - 0.00061 19.7 0.2 0.0013 18.7 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAI99320.1 - 0.0015 18.2 0.2 0.0023 17.5 0.1 1.3 1 0 0 1 1 1 1 Barwin family DUF3918 PF13056.1 OAI99320.1 - 0.11 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Cyclin_N PF00134.18 OAI99326.1 - 9.1e-22 76.9 0.2 7.3e-20 70.8 0.0 2.7 2 1 1 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAI99326.1 - 7.2e-16 58.1 0.0 1.6e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DZF PF07528.9 OAI99326.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 DZF domain Oxygenase-NA PF09859.4 OAI99326.1 - 0.048 12.9 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA HOOK PF05622.7 OAI99328.1 - 0.00081 17.3 0.8 0.001 17.0 0.6 1.0 1 0 0 1 1 1 1 HOOK protein Apolipoprotein PF01442.13 OAI99328.1 - 0.0011 18.5 0.8 0.0016 18.0 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 OAI99328.1 - 0.023 14.5 3.9 0.43 10.3 0.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 OAI99328.1 - 0.03 13.4 0.5 0.04 13.0 0.3 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF4164 PF13747.1 OAI99328.1 - 0.03 14.4 0.7 0.03 14.4 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HsbA PF12296.3 OAI99328.1 - 0.11 12.3 2.1 6.3 6.6 0.1 2.2 1 1 1 2 2 2 0 Hydrophobic surface binding protein A PIF1 PF05970.9 OAI99329.1 - 2.1e-20 73.0 0.0 7.7e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAI99329.1 - 7.6e-11 41.9 0.0 9.7e-10 38.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAI99329.1 - 2.2e-08 34.0 0.0 4.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAI99329.1 - 1.4e-07 31.1 0.1 1.4e-07 31.1 0.1 3.3 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAI99329.1 - 0.0037 17.2 0.2 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAI99329.1 - 0.028 14.5 0.0 0.074 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAI99329.1 - 0.042 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain UvrD_C_2 PF13538.1 OAI99329.1 - 0.12 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pkinase PF00069.20 OAI99337.1 - 3.1e-59 200.2 0.0 7.8e-33 113.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99337.1 - 1.6e-19 69.9 0.0 3e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 OAI99337.1 - 0.0063 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAI99337.1 - 0.15 11.7 5.5 0.1 12.3 0.2 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family Nop14 PF04147.7 OAI99337.1 - 0.78 7.5 19.6 1.3 6.8 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 OAI99337.1 - 0.87 8.1 2.7 1.2 7.6 1.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 OAI99337.1 - 1 7.1 14.5 1.9 6.2 10.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIF_alpha PF05793.7 OAI99337.1 - 3 6.1 16.5 4.5 5.5 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FLO_LFY PF01698.11 OAI99337.1 - 7.1 5.3 8.9 15 4.3 6.2 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein GCR1_C PF12550.3 OAI99338.1 - 6.3e-21 74.0 0.1 1.3e-20 73.0 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_int_SAM_1 PF02899.12 OAI99338.1 - 0.048 13.8 2.1 0.14 12.3 0.1 2.8 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Ribosomal_L22 PF00237.14 OAI99339.1 - 6.1e-33 112.9 0.1 9.4e-33 112.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L23eN PF03939.8 OAI99340.1 - 8.5e-21 73.7 12.2 1.5e-20 72.9 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 OAI99340.1 - 2.5e-12 46.5 0.1 5e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 MCM PF00493.18 OAI99341.1 - 1.7e-138 460.9 0.0 2.3e-138 460.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 OAI99341.1 - 1.1e-32 113.2 33.4 1.1e-32 113.2 23.2 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 OAI99341.1 - 8.2e-19 68.2 0.1 2.5e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAI99341.1 - 1.3e-08 34.2 0.0 6.3e-07 28.7 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAI99341.1 - 6.7e-06 25.8 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAI99341.1 - 0.00064 19.3 0.0 0.0093 15.5 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_gyraseB_C PF00986.16 OAI99341.1 - 0.021 14.5 0.2 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus Sigma54_activat PF00158.21 OAI99341.1 - 0.042 13.3 0.0 0.29 10.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 OAI99341.1 - 0.16 12.3 0.2 0.38 11.1 0.2 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain DHBP_synthase PF00926.14 OAI99342.1 - 6e-70 234.4 0.0 7.2e-70 234.1 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Cyt-b5 PF00173.23 OAI99343.1 - 2e-10 40.2 0.0 2.6e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Septin PF00735.13 OAI99344.1 - 2.8e-41 141.3 5.1 2.2e-15 56.4 0.0 4.9 5 0 0 5 5 5 4 Septin TFIIF_alpha PF05793.7 OAI99344.1 - 0.0011 17.3 2.9 0.0011 17.3 2.0 2.2 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIA PF03153.8 OAI99344.1 - 0.0062 16.4 17.0 0.0062 16.4 11.8 3.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 OAI99344.1 - 0.029 13.8 0.0 12 5.2 0.0 3.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AvrE PF11725.3 OAI99344.1 - 0.031 11.3 10.9 0.044 10.8 7.5 1.1 1 0 0 1 1 1 0 Pathogenicity factor zf-RING_2 PF13639.1 OAI99345.1 - 2.8e-14 52.6 6.4 4.4e-14 52.0 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAI99345.1 - 3.5e-10 39.8 1.6 6.2e-10 39.0 1.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAI99345.1 - 4.7e-08 32.9 4.5 7.3e-08 32.3 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI99345.1 - 6.9e-08 32.0 3.6 1.1e-07 31.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI99345.1 - 3.5e-07 29.8 2.4 5.3e-07 29.2 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAI99345.1 - 4.3e-07 29.4 2.6 6.9e-07 28.8 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAI99345.1 - 6.5e-06 25.8 1.0 1.2e-05 25.0 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 OAI99345.1 - 0.004 16.7 4.2 0.0067 15.9 2.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 OAI99345.1 - 0.0078 16.1 2.1 0.014 15.3 1.4 1.3 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.2 OAI99345.1 - 0.038 14.0 7.0 0.063 13.3 4.9 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 OAI99345.1 - 0.16 11.6 4.7 0.27 10.9 3.2 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 OAI99345.1 - 1.7 8.6 3.3 3.4 7.6 2.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 OAI99345.1 - 2.4 8.0 3.3 9.9 6.1 2.5 1.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 OAI99345.1 - 3.5 7.4 4.4 0.95 9.2 0.8 1.6 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 Na_Ca_ex PF01699.19 OAI99348.1 - 6.5e-43 145.6 31.4 6.4e-22 77.6 6.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ceramidase PF05875.7 OAI99348.1 - 0.029 13.5 2.8 0.28 10.2 0.0 2.6 2 1 0 2 2 2 0 Ceramidase DUF3317 PF11779.3 OAI99348.1 - 4.6 6.7 8.7 1.7 8.1 0.2 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DUF3742 PF12553.3 OAI99348.1 - 7.2 7.1 7.1 31 5.1 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3742) MAPEG PF01124.13 OAI99350.1 - 2.7e-25 88.4 1.8 3.2e-25 88.2 1.3 1.0 1 0 0 1 1 1 1 MAPEG family NTF2 PF02136.15 OAI99352.1 - 1.7e-30 105.8 0.1 2.4e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 OAI99352.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RNA_pol_Rpb4 PF03874.11 OAI99353.1 - 2.5e-14 53.2 0.4 3.6e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 AKAP2_C PF15304.1 OAI99353.1 - 0.15 11.6 1.2 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DapB_C PF05173.9 OAI99354.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus adh_short PF00106.20 OAI99355.1 - 4.1e-15 56.1 0.4 8.8e-15 55.0 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI99355.1 - 4.9e-08 32.8 0.2 1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAI99355.1 - 0.00013 21.7 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 OAI99355.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mito_carr PF00153.22 OAI99356.1 - 1.7e-10 40.4 0.2 0.0026 17.4 0.0 3.7 3 0 0 3 3 3 2 Mitochondrial carrier protein HTH_OrfB_IS605 PF12323.3 OAI99359.1 - 3.6e-09 35.7 0.6 8e-09 34.6 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1778 PF08681.6 OAI99359.1 - 0.046 13.5 1.1 0.19 11.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1778) Malate_DH PF12434.3 OAI99359.1 - 0.091 12.4 0.7 0.25 11.0 0.5 1.7 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Mucin PF01456.12 OAI99360.1 - 0.53 10.0 19.3 0.66 9.7 13.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.22 OAI99361.1 - 4.8e-15 55.4 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99361.1 - 7.1e-14 51.9 0.1 1.3e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99361.1 - 0.0002 21.8 0.0 0.00075 19.9 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99361.1 - 0.069 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Sporozoite_P67 PF05642.6 OAI99362.1 - 6.8e-05 20.9 0.2 8e-05 20.7 0.1 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Drf_FH1 PF06346.7 OAI99362.1 - 0.0078 15.7 6.7 0.0078 15.7 4.7 1.8 2 0 0 2 2 2 1 Formin Homology Region 1 DUF2406 PF10295.4 OAI99364.1 - 0.11 12.9 1.2 0.25 11.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) V-SNARE_C PF12352.3 OAI99367.1 - 0.055 13.5 2.1 0.23 11.5 0.3 2.6 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus HR1 PF02185.11 OAI99367.1 - 0.077 12.7 0.3 0.077 12.7 0.2 2.5 3 0 0 3 3 3 0 Hr1 repeat MT PF12777.2 OAI99367.1 - 0.16 10.7 5.1 0.31 9.7 0.6 2.3 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor Tropomyosin PF00261.15 OAI99367.1 - 0.31 10.0 10.8 0.1 11.6 4.0 2.2 2 0 0 2 2 2 0 Tropomyosin DUF3708 PF12501.3 OAI99367.1 - 1.8 8.3 11.2 5 6.9 0.3 2.4 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter NPV_P10 PF05531.7 OAI99367.1 - 2.7 8.2 5.6 4.7 7.5 0.8 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 OAI99367.1 - 2.9 6.2 8.0 0.62 8.4 2.9 1.6 1 1 1 2 2 2 0 AAA domain COPIIcoated_ERV PF07970.7 OAI99372.1 - 8.7e-64 215.1 1.6 5.8e-34 117.6 0.2 2.3 2 1 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAI99372.1 - 1.5e-31 108.2 0.3 3.6e-31 106.9 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RWD PF05773.17 OAI99375.1 - 6.6e-19 67.8 0.2 1.1e-18 67.1 0.1 1.4 1 0 0 1 1 1 1 RWD domain GMC_oxred_C PF05199.8 OAI99375.1 - 0.081 13.2 0.2 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase MULE PF10551.4 OAI99376.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAI99376.1 - 7.9e-06 26.3 0.5 7.9e-06 26.3 0.3 3.1 4 0 0 4 4 4 1 FAR1 DNA-binding domain AFT PF08731.6 OAI99376.1 - 0.0023 18.1 0.2 0.0023 18.1 0.1 1.9 2 0 0 2 2 2 1 Transcription factor AFT PNPOx_C PF10590.4 OAI99377.1 - 6.3e-20 70.3 3.4 1.2e-19 69.5 2.3 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 OAI99377.1 - 1.5e-17 63.4 0.0 8.4e-16 57.7 0.0 2.3 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Alpha-amylase PF00128.19 OAI99377.1 - 0.061 12.7 0.4 0.21 10.9 0.3 1.7 1 1 1 2 2 2 0 Alpha amylase, catalytic domain RNase_H2_suC PF08615.6 OAI99378.1 - 3.9e-14 52.6 19.6 2.1e-12 47.0 0.1 4.7 3 2 0 3 3 3 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CAP PF00188.21 OAI99379.1 - 4.1e-21 75.7 0.2 4.1e-21 75.7 0.1 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TFIIA PF03153.8 OAI99379.1 - 0.041 13.7 10.0 0.054 13.3 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Formyl_trans_N PF00551.14 OAI99380.1 - 6.7e-34 117.0 0.0 1.2e-32 112.8 0.0 2.4 1 1 0 1 1 1 1 Formyl transferase MAS20 PF02064.10 OAI99381.1 - 2.7e-14 53.1 0.1 3.3e-13 49.5 0.1 2.2 1 1 0 1 1 1 1 MAS20 protein import receptor Macoilin PF09726.4 OAI99381.1 - 2.9 6.0 14.3 5.6 5.1 9.9 1.5 1 0 0 1 1 1 0 Transmembrane protein Thioredoxin PF00085.15 OAI99382.1 - 4.9e-29 100.0 0.0 2.9e-22 78.2 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.1 OAI99382.1 - 2.3e-06 27.5 0.0 0.00081 19.3 0.1 3.2 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAI99382.1 - 6e-06 26.4 2.2 5.5e-05 23.3 0.3 3.1 2 2 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAI99382.1 - 0.00018 21.1 0.1 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 OAI99382.1 - 0.0034 17.4 0.2 0.046 13.8 0.1 2.4 1 1 1 2 2 2 1 Thioredoxin-like DDE_Tnp_4 PF13359.1 OAI99386.1 - 1.4e-32 112.4 0.0 2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAI99386.1 - 5.8e-09 35.6 0.0 6.4e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAI99386.1 - 0.00012 21.6 0.0 0.0013 18.2 0.0 2.1 1 1 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 OAI99387.1 - 0.066 13.8 0.2 0.087 13.4 0.1 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MIP-T3 PF10243.4 OAI99388.1 - 0.079 11.4 39.1 0.11 10.9 27.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 OAI99388.1 - 2.9 6.0 22.5 3.9 5.5 15.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NTP_transf_2 PF01909.18 OAI99389.1 - 0.0025 18.1 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Xan_ur_permease PF00860.15 OAI99394.1 - 2.3e-26 92.2 28.1 2.6e-13 49.2 5.6 2.2 2 0 0 2 2 2 2 Permease family Sulfate_transp PF00916.15 OAI99394.1 - 0.00065 18.8 5.3 0.0011 18.0 3.0 1.9 1 1 0 1 1 1 1 Sulfate transporter family PK PF00224.16 OAI99395.1 - 3.2e-159 529.1 1.3 4e-159 528.8 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 OAI99395.1 - 3.5e-32 110.3 0.0 1.2e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 OAI99395.1 - 6e-05 22.0 2.5 0.00013 20.9 0.9 2.3 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 OAI99395.1 - 0.00026 19.9 0.1 0.0047 15.8 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.13 OAI99395.1 - 0.022 13.9 0.0 0.045 12.9 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Peptidase_U32 PF01136.14 OAI99395.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family U32 Zn_clus PF00172.13 OAI99396.1 - 1.8e-05 24.5 6.2 3.1e-05 23.7 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.4 OAI99396.1 - 0.048 13.4 0.7 0.094 12.5 0.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Rxt3 PF08642.5 OAI99397.1 - 1.1e-14 54.6 14.1 7.4e-11 42.3 0.0 4.1 3 1 0 3 3 3 2 Histone deacetylation protein Rxt3 LCCL PF03815.14 OAI99397.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 LCCL domain Tho2 PF11262.3 OAI99398.1 - 8.1e-60 202.3 1.2 4.3e-59 199.9 0.8 1.9 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 OAI99398.1 - 8.1e-22 76.8 0.0 1.8e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RRM_1 PF00076.17 OAI99399.1 - 5.6e-32 109.1 1.1 5e-20 70.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAI99399.1 - 1e-24 86.2 0.1 2.4e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAI99399.1 - 3.4e-08 33.2 0.0 1.2e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAI99399.1 - 0.0053 16.4 0.0 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 API5 PF05918.6 OAI99399.1 - 0.015 13.7 11.0 0.021 13.3 7.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2205 PF10224.4 OAI99403.1 - 2.3e-15 55.9 0.0 2.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 OAI99403.1 - 0.0021 18.3 0.1 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Cast PF10174.4 OAI99403.1 - 0.045 11.8 0.1 0.049 11.6 0.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone OmpH PF03938.9 OAI99404.1 - 6.6e-05 22.8 8.8 0.00014 21.8 3.2 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF1071 PF06378.6 OAI99404.1 - 0.038 13.1 3.4 0.095 11.8 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Proteasome PF00227.21 OAI99405.1 - 5.6e-51 172.5 0.0 7.3e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAI99405.1 - 1.2e-11 43.7 0.1 2e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Mito_carr PF00153.22 OAI99406.1 - 6.9e-65 214.8 1.1 4.4e-21 74.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein CPSase_L_D2 PF02786.12 OAI99407.1 - 4.2e-105 349.6 0.0 6e-82 274.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 OAI99407.1 - 2.9e-41 140.0 0.1 6.3e-41 139.0 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 OAI99407.1 - 4e-35 121.2 0.1 3e-17 62.9 0.1 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 OAI99407.1 - 7.4e-34 116.1 0.0 1e-15 57.7 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 OAI99407.1 - 1.2e-23 83.4 0.0 5.7e-08 31.8 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAI99407.1 - 5.3e-16 58.4 0.0 1.2e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAI99407.1 - 1.6e-11 44.0 0.0 0.00018 20.9 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 OAI99407.1 - 8.6e-08 31.8 0.0 0.00025 20.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAI99407.1 - 6.4e-07 29.3 0.0 0.00016 21.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MT-A70 PF05063.9 OAI99407.1 - 6.9e-07 28.9 0.1 0.0015 18.1 0.2 3.5 2 1 0 2 2 2 1 MT-A70 ATP-grasp_5 PF13549.1 OAI99407.1 - 4.4e-05 22.7 0.1 0.044 12.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 OAI99407.1 - 0.0029 17.5 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 1 1 MGS-like domain GARS_A PF01071.14 OAI99407.1 - 0.047 13.2 0.1 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain V-ATPase_G PF03179.10 OAI99408.1 - 3.8e-33 113.9 17.1 4.4e-33 113.7 11.8 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 OAI99408.1 - 0.011 15.4 12.0 0.011 15.4 8.3 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) CagA PF03507.8 OAI99408.1 - 0.071 12.9 2.6 0.13 12.1 1.8 1.6 1 1 0 1 1 1 0 CagA exotoxin SpoIID PF08486.5 OAI99408.1 - 0.074 13.3 1.9 0.12 12.6 1.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein DUF2115 PF09888.4 OAI99408.1 - 0.23 11.5 2.8 0.28 11.2 2.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF2317 PF10079.4 OAI99408.1 - 0.41 9.2 13.1 0.49 8.9 9.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) ADPrib_exo_Tox PF03496.9 OAI99408.1 - 0.44 9.7 4.9 1.1 8.3 0.1 2.1 1 1 1 2 2 2 0 ADP-ribosyltransferase exoenzyme DUF3402 PF11882.3 OAI99408.1 - 0.46 9.4 6.7 0.47 9.4 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) PTPlike_phytase PF14566.1 OAI99408.1 - 0.55 10.2 3.5 0.64 10.0 2.4 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4375 PF14300.1 OAI99408.1 - 0.59 10.1 6.4 3.1 7.7 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4375) DUF1104 PF06518.6 OAI99408.1 - 0.65 10.1 11.1 1.2 9.3 7.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1104) Plasmid_killer PF05015.8 OAI99408.1 - 0.8 9.8 3.7 1.2 9.3 1.3 1.9 1 1 2 3 3 3 0 Plasmid maintenance system killer protein Seryl_tRNA_N PF02403.17 OAI99408.1 - 0.89 9.5 14.2 2.4 8.2 9.2 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HrpE PF06188.7 OAI99408.1 - 1.3 8.7 10.4 1.6 8.4 7.2 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_F6 PF05511.6 OAI99408.1 - 1.3 8.9 6.4 2.7 7.9 1.5 2.2 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF4407 PF14362.1 OAI99408.1 - 1.4 7.8 14.1 1.5 7.6 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.3 OAI99408.1 - 1.6 7.8 20.6 3.5 6.8 14.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) TMPIT PF07851.8 OAI99408.1 - 2.4 7.1 6.1 2.7 6.9 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein SprA-related PF12118.3 OAI99408.1 - 2.7 7.2 15.4 2.9 7.1 10.7 1.0 1 0 0 1 1 1 0 SprA-related family AIF-MLS PF14962.1 OAI99408.1 - 4.6 6.8 8.3 6 6.4 5.6 1.4 1 1 0 1 1 1 0 Mitochondria Localisation Sequence DDHD PF02862.12 OAI99408.1 - 6.7 6.4 8.1 7.3 6.3 5.6 1.0 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.5 OAI99408.1 - 9.9 6.1 14.1 11 6.0 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_B PF00136.16 OAI99409.1 - 4.4e-149 497.2 0.4 7.2e-149 496.5 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAI99409.1 - 1.2e-78 264.2 0.0 3.9e-78 262.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAI99409.1 - 3.1e-22 78.3 7.2 6.8e-22 77.2 5.0 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 OAI99409.1 - 0.0027 17.2 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAI99409.1 - 0.0056 16.5 0.4 0.023 14.5 0.1 2.3 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 OAI99409.1 - 0.039 12.6 1.9 0.06 11.9 0.0 2.1 3 0 0 3 3 3 0 DNA polymerase type B, organellar and viral zf-RING-like PF08746.6 OAI99409.1 - 0.28 11.2 5.7 0.06 13.3 0.7 2.4 2 0 0 2 2 2 0 RING-like domain HypA PF01155.14 OAI99409.1 - 4.1 7.1 7.3 14 5.3 0.7 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 OAI99409.1 - 9.4 6.1 10.2 0.24 11.2 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Peptidase_C65 PF10275.4 OAI99410.1 - 2.8e-59 200.4 0.0 3.5e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 OAI99410.1 - 9e-05 23.0 0.0 0.00079 20.0 0.0 2.1 1 1 0 1 1 1 1 OTU-like cysteine protease Ric8 PF10165.4 OAI99410.1 - 0.079 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn E3_binding PF02817.12 OAI99412.1 - 7.3e-10 38.3 0.1 1.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Amino_oxidase PF01593.19 OAI99413.1 - 3.6e-53 181.2 0.3 4.8e-53 180.8 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAI99413.1 - 1.3e-11 44.3 0.6 2.9e-11 43.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAI99413.1 - 5.6e-08 32.0 1.0 3.6e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 OAI99413.1 - 6.7e-07 28.1 2.4 0.0029 16.1 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 OAI99413.1 - 1.9e-05 23.7 1.7 3.3e-05 22.9 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 OAI99413.1 - 3.8e-05 23.9 0.2 0.00032 21.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI99413.1 - 5.5e-05 23.3 0.5 0.1 12.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAI99413.1 - 0.00053 19.1 0.9 0.00088 18.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 OAI99413.1 - 0.00066 19.4 0.7 1.1 8.9 0.1 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 OAI99413.1 - 0.0033 16.3 0.2 1.5 7.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAI99413.1 - 0.0034 17.2 0.3 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI99413.1 - 0.0097 15.0 0.4 0.017 14.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 OAI99413.1 - 0.093 11.7 1.1 0.16 11.0 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAI99413.1 - 0.28 9.9 1.3 0.93 8.2 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A RRN7 PF11781.3 OAI99414.1 - 0.16 11.4 3.4 0.41 10.1 2.3 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 FYVE_2 PF02318.11 OAI99414.1 - 0.89 9.4 4.4 1.4 8.8 3.1 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger FYDLN_acid PF09538.5 OAI99414.1 - 2.6 8.6 11.2 1.3 9.6 5.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Rep_fac-A_C PF08646.5 OAI99414.1 - 8.7 6.0 8.2 14 5.3 5.7 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain PIF1 PF05970.9 OAI99415.1 - 6.5e-13 48.3 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 OAI99415.1 - 7.1e-09 35.2 0.2 1.8e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAI99415.1 - 1.2e-08 34.7 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAI99415.1 - 1.3e-05 25.3 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 OAI99415.1 - 6.9e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 OAI99415.1 - 0.00013 21.8 0.0 0.00056 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAI99415.1 - 0.00026 18.8 0.2 0.0064 14.2 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.1 OAI99415.1 - 0.00063 19.3 0.0 0.0036 16.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 OAI99415.1 - 0.00074 19.5 0.1 0.0029 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 OAI99415.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.6 1 1 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.13 OAI99415.1 - 0.0013 18.3 0.1 0.24 10.8 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 OAI99415.1 - 0.005 16.2 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAI99415.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 OAI99415.1 - 0.0078 15.9 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 OAI99415.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 OAI99415.1 - 0.012 14.8 0.2 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 OAI99415.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit cobW PF02492.14 OAI99415.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 OAI99415.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 OAI99415.1 - 0.035 13.8 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 OAI99415.1 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 OAI99415.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 1 0 NTPase UPF0079 PF02367.12 OAI99415.1 - 0.046 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 OAI99415.1 - 0.05 13.1 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 OAI99415.1 - 0.061 11.9 0.0 0.091 11.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 OAI99415.1 - 0.062 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_32 PF13654.1 OAI99415.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAI99415.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAI99415.1 - 0.11 12.0 0.0 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA12 PF10443.4 OAI99415.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DEAD PF00270.24 OAI99415.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_17 PF13207.1 OAI99415.1 - 0.14 12.9 0.0 0.36 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAI99415.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAI99415.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain JmjC PF02373.17 OAI99416.1 - 5.1e-06 26.6 0.0 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-RING_4 PF14570.1 OAI99416.1 - 1.7 8.3 8.8 0.089 12.3 2.3 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 OAI99416.1 - 1.7 8.3 5.6 0.41 10.3 0.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 DEAD PF00270.24 OAI99417.1 - 4.4e-12 45.8 0.1 1.3e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI99417.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF87 PF01935.12 OAI99417.1 - 0.19 11.5 0.3 0.43 10.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 zf-C2H2 PF00096.21 OAI99417.1 - 0.49 10.8 13.9 0.48 10.8 2.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 OAI99417.1 - 1.2 9.5 5.8 6.5 7.2 1.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 OAI99417.1 - 2.6 8.2 7.4 7.9 6.7 2.6 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding JmjC PF02373.17 OAI99419.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase C1_1 PF00130.17 OAI99419.1 - 0.021 14.5 4.5 0.05 13.3 3.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UDP PF14569.1 OAI99419.1 - 0.29 10.9 6.2 4.8 6.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-CCCH PF00642.19 OAI99426.1 - 1.7e-05 24.3 27.4 7.9e-05 22.2 1.9 4.5 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BAR PF03114.13 OAI99427.1 - 1.4e-49 168.6 1.4 1.7e-49 168.4 1.0 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 OAI99427.1 - 5.7e-06 25.8 1.1 7.3e-06 25.4 0.7 1.1 1 0 0 1 1 1 1 Arfaptin-like domain AAA_13 PF13166.1 OAI99427.1 - 0.027 12.9 0.6 0.042 12.3 0.4 1.3 1 1 0 1 1 1 0 AAA domain Cellulase PF00150.13 OAI99428.1 - 7.1e-09 35.2 0.7 7.1e-09 35.2 0.5 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Chalcone PF02431.10 OAI99429.1 - 5.5e-41 140.1 0.0 8.5e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase AKAP2_C PF15304.1 OAI99429.1 - 0.053 13.1 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Med31 PF05669.7 OAI99430.1 - 3.1e-27 94.3 0.0 3.5e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 SOH1 SIR2 PF02146.12 OAI99431.1 - 4.2e-25 88.4 0.1 5.6e-19 68.5 0.0 3.6 3 1 0 3 3 3 2 Sir2 family Tad PF13400.1 OAI99432.1 - 2.8 8.0 6.9 0.24 11.4 0.7 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Atx10homo_assoc PF09759.4 OAI99433.1 - 3.9e-18 65.0 0.0 1.6e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Retrotrans_gag PF03732.12 OAI99437.1 - 0.0022 18.0 1.0 0.024 14.7 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein DUF4407 PF14362.1 OAI99437.1 - 0.058 12.3 0.3 0.097 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-B_dimeris PF09026.5 OAI99440.1 - 0.3 11.3 11.2 0.41 10.9 1.6 3.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ACOX PF01756.14 OAI99441.1 - 4.8e-38 130.4 0.3 1.4e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAI99441.1 - 4.7e-23 81.8 0.3 1e-22 80.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 OAI99441.1 - 4.9e-10 38.7 0.2 1.3e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 OAI99441.1 - 0.00017 21.7 0.5 0.0075 16.3 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RVT_1 PF00078.22 OAI99442.1 - 1.6e-16 60.3 0.0 3.1e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99442.1 - 8.3e-16 58.1 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99442.1 - 0.00025 21.4 0.0 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAI99442.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAI99442.1 - 0.016 14.9 0.3 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.8 OAI99442.1 - 0.4 9.0 0.0 0.66 8.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein NMO PF03060.10 OAI99443.1 - 6.4e-52 176.7 0.6 5.8e-51 173.5 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 OAI99443.1 - 2.3e-07 30.0 0.9 0.0079 15.1 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 OAI99443.1 - 0.0013 17.6 0.1 0.0023 16.8 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAI99443.1 - 0.022 14.0 0.1 0.046 12.9 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF1902 PF08972.6 OAI99443.1 - 0.11 12.1 0.3 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) ATP_bind_3 PF01171.15 OAI99444.1 - 1e-05 25.1 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PP-loop family RsbRD_N PF14361.1 OAI99444.1 - 0.089 13.2 0.3 0.49 10.8 0.0 2.2 1 1 1 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF2267 PF10025.4 OAI99444.1 - 0.79 9.7 3.4 0.93 9.5 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2267) Asn_synthase PF00733.16 OAI99446.1 - 0.0026 17.2 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.15 OAI99446.1 - 0.0037 16.7 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 2 PP-loop family DUF4449 PF14613.1 OAI99449.1 - 2.1e-25 89.5 0.1 2.1e-25 89.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Con-6 PF10346.4 OAI99450.1 - 8.5e-09 34.6 0.2 1.7e-08 33.7 0.1 1.6 1 1 0 1 1 1 1 Conidiation protein 6 Glyco_hydro_43 PF04616.9 OAI99451.1 - 1.1e-35 123.0 0.4 1.3e-35 122.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 NAD_binding_10 PF13460.1 OAI99452.1 - 0.0011 18.9 0.0 0.012 15.6 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding UPF0029 PF01205.14 OAI99454.1 - 1.1e-16 60.5 0.0 2.8e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PaaX PF07848.7 OAI99454.1 - 0.034 14.1 0.5 0.83 9.6 0.0 2.7 2 0 0 2 2 2 0 PaaX-like protein CTP_transf_2 PF01467.21 OAI99455.1 - 5.6e-09 36.2 0.0 6.9e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 OAI99455.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase CAP_N PF01213.14 OAI99456.1 - 4.8e-81 272.4 0.2 1.8e-79 267.2 0.1 2.2 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 OAI99456.1 - 2.2e-53 179.8 2.6 2.9e-53 179.4 1.8 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Amidase_5 PF05382.8 OAI99456.1 - 0.0081 15.7 0.2 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase TBCC PF07986.7 OAI99456.1 - 0.025 13.9 3.7 0.049 13.0 2.6 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor C Mito_fiss_reg PF05308.6 OAI99456.1 - 0.12 11.7 5.6 0.47 9.7 0.5 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Abhydrolase_6 PF12697.2 OAI99457.1 - 0.024 14.5 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99457.1 - 0.028 14.1 0.1 0.1 12.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family WD40 PF00400.27 OAI99458.1 - 2.4e-11 43.0 5.3 5.2e-06 26.1 0.0 3.7 4 1 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAI99458.1 - 0.0044 15.8 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like Oxysterol_BP PF01237.13 OAI99463.1 - 4.5e-58 196.4 2.2 2.1e-45 154.7 0.0 3.0 3 0 0 3 3 3 3 Oxysterol-binding protein Sigma70_ner PF04546.8 OAI99464.1 - 0.16 11.5 13.2 0.34 10.5 3.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 OAI99464.1 - 2.7 7.5 9.8 9.5 5.7 2.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin NUDIX PF00293.23 OAI99465.1 - 7.4e-15 54.7 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 OAI99465.1 - 7.5e-11 42.2 2.7 8.9e-10 38.7 1.9 2.6 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Pyr_redox_2 PF07992.9 OAI99466.1 - 6.6e-41 140.4 0.2 1.1e-40 139.7 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 OAI99466.1 - 1.7e-35 121.3 0.7 4.3e-35 120.0 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 OAI99466.1 - 1.7e-20 73.2 6.3 1.4e-18 67.0 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI99466.1 - 1.1e-14 55.0 0.0 1.3e-08 35.1 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAI99466.1 - 3.5e-07 29.0 0.8 0.026 12.9 0.0 3.1 3 0 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.2 OAI99466.1 - 6.4e-05 22.2 0.0 0.00018 20.7 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 OAI99466.1 - 0.0001 21.3 0.0 0.00035 19.5 0.0 1.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 OAI99466.1 - 0.016 14.9 3.1 0.092 12.3 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 OAI99466.1 - 0.016 15.2 2.4 0.054 13.5 1.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAI99466.1 - 0.029 14.1 0.0 3.9 7.2 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAI99466.1 - 0.03 13.1 2.8 0.53 9.0 1.5 2.4 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 OAI99466.1 - 0.033 13.3 0.4 0.069 12.2 0.3 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 OAI99466.1 - 0.054 13.7 0.1 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 OAI99466.1 - 0.23 10.3 7.2 0.98 8.2 0.2 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase Lipase_3 PF01764.20 OAI99467.1 - 3.5e-14 52.6 0.0 5.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 OAI99467.1 - 0.0063 16.1 0.1 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 OAI99467.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) U79_P34 PF03064.11 OAI99467.1 - 0.27 10.7 9.7 1.5 8.2 6.8 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 ATPase_gene1 PF09527.5 OAI99468.1 - 0.93 9.3 4.7 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF1664 PF07889.7 OAI99469.1 - 0.29 10.9 5.3 0.32 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 OAI99469.1 - 0.44 10.6 7.6 1.1 9.3 5.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 OAI99469.1 - 0.52 10.2 1.7 11 6.0 0.2 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) GAS PF13851.1 OAI99469.1 - 7 5.7 21.8 8.8 5.4 9.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3382 PF11862.3 OAI99473.1 - 0.055 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Nop14 PF04147.7 OAI99474.1 - 0.0016 16.4 14.5 0.002 16.1 10.1 1.1 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 OAI99474.1 - 0.013 14.0 15.4 0.015 13.8 10.7 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAI99474.1 - 0.014 14.7 14.8 0.018 14.3 10.3 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAI99474.1 - 0.18 9.8 12.5 0.22 9.5 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 OAI99474.1 - 0.36 10.2 8.5 0.45 9.9 5.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO COPI_C PF06957.6 OAI99474.1 - 0.78 8.1 6.1 0.98 7.8 4.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus eIF-3c_N PF05470.7 OAI99474.1 - 4.8 5.1 9.7 5.5 4.9 6.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ank_2 PF12796.2 OAI99475.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) rve PF00665.21 OAI99476.1 - 1e-15 57.9 0.0 2.9e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAI99476.1 - 1.1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SBF PF01758.11 OAI99478.1 - 2.5e-39 134.6 15.6 2.5e-39 134.6 10.8 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family Asp_protease_2 PF13650.1 OAI99479.1 - 1.2e-08 35.3 0.0 3e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99479.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 OAI99479.1 - 0.0045 16.5 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAI99479.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 OAI99479.1 - 0.23 11.3 0.1 0.9 9.4 0.0 2.0 3 0 0 3 3 3 0 Retroviral aspartyl protease DUF3128 PF11326.3 OAI99482.1 - 6.2e-20 71.1 2.8 6.7e-20 71.0 1.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) DnaJ PF00226.26 OAI99483.1 - 0.11 12.2 0.0 27 4.6 0.0 2.7 3 0 0 3 3 3 0 DnaJ domain UQ_con PF00179.21 OAI99484.1 - 1.3e-31 108.8 0.0 2.1e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HMG_box PF00505.14 OAI99485.1 - 3.3e-10 40.0 3.0 3.7e-07 30.3 0.8 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box DUF659 PF04937.10 OAI99486.1 - 0.00038 19.9 0.0 0.001 18.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 OAI99486.1 - 0.064 12.8 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pex14_N PF04695.8 OAI99487.1 - 5.2e-30 104.2 0.0 5.2e-30 104.2 0.0 3.9 2 1 0 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 OAI99487.1 - 1.2e-06 28.2 3.0 2.4e-06 27.2 2.1 1.4 1 0 0 1 1 1 1 IncA protein ERM PF00769.14 OAI99487.1 - 0.00022 20.8 0.7 0.00033 20.2 0.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family NPV_P10 PF05531.7 OAI99487.1 - 0.00055 20.1 6.1 0.028 14.6 0.5 2.9 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein MAD PF05557.8 OAI99487.1 - 0.00089 17.4 3.0 0.0013 16.9 2.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Laminin_II PF06009.7 OAI99487.1 - 0.0026 17.5 3.8 0.0026 17.5 2.6 2.2 1 1 0 1 1 1 1 Laminin Domain II IFT57 PF10498.4 OAI99487.1 - 0.003 16.3 2.9 0.0052 15.5 2.0 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 zf-C4H2 PF10146.4 OAI99487.1 - 0.0031 17.5 0.2 0.0031 17.5 0.1 1.8 2 0 0 2 2 2 1 Zinc finger-containing protein Atg14 PF10186.4 OAI99487.1 - 0.0045 15.9 1.0 0.0069 15.3 0.7 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EzrA PF06160.7 OAI99487.1 - 0.0047 15.1 3.0 0.0071 14.5 2.1 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA PilJ PF13675.1 OAI99487.1 - 0.0049 17.1 6.8 0.014 15.7 2.4 2.8 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term AAA_13 PF13166.1 OAI99487.1 - 0.006 15.1 2.6 0.0083 14.6 1.8 1.1 1 0 0 1 1 1 1 AAA domain TBPIP PF07106.8 OAI99487.1 - 0.0093 15.5 4.9 0.011 15.2 1.3 2.0 1 1 1 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 OAI99487.1 - 0.01 13.2 9.5 0.014 12.8 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF1395 PF07160.7 OAI99487.1 - 0.018 14.5 1.4 0.028 13.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Baculo_PEP_C PF04513.7 OAI99487.1 - 0.02 14.7 1.2 0.065 13.0 0.8 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sipho_Gp157 PF05565.6 OAI99487.1 - 0.028 13.9 4.2 0.045 13.3 2.9 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 PV-1 PF06637.6 OAI99487.1 - 0.032 12.8 1.0 0.042 12.4 0.7 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1759 PF03564.10 OAI99487.1 - 0.04 13.7 0.5 0.074 12.8 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) DUF4407 PF14362.1 OAI99487.1 - 0.046 12.6 3.0 0.076 11.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2968 PF11180.3 OAI99487.1 - 0.047 13.0 13.2 0.13 11.5 9.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 OAI99487.1 - 0.055 12.4 9.7 0.081 11.9 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CR6_interact PF10147.4 OAI99487.1 - 0.089 12.0 4.5 0.13 11.5 3.1 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF342 PF03961.8 OAI99487.1 - 0.11 10.8 3.2 0.18 10.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HisKA_3 PF07730.8 OAI99487.1 - 0.2 12.0 5.5 0.11 12.8 0.6 2.4 2 0 0 2 2 2 0 Histidine kinase RmuC PF02646.11 OAI99487.1 - 0.21 10.3 4.6 0.11 11.3 1.5 1.6 1 1 1 2 2 2 0 RmuC family Allexi_40kDa PF05549.6 OAI99487.1 - 0.22 10.7 2.6 2 7.6 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein FlgN PF05130.7 OAI99487.1 - 0.24 11.6 11.5 0.4 10.9 8.0 1.3 1 0 0 1 1 1 0 FlgN protein DUF948 PF06103.6 OAI99487.1 - 0.26 11.1 3.0 3.6 7.5 0.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 OAI99487.1 - 0.26 9.8 6.9 0.48 9.0 4.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 OAI99487.1 - 0.32 10.9 12.7 0.068 13.1 6.4 1.6 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 OAI99487.1 - 0.35 9.8 1.8 0.55 9.2 1.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2317 PF10079.4 OAI99487.1 - 0.36 9.3 5.0 0.51 8.8 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) HALZ PF02183.13 OAI99487.1 - 0.55 9.9 8.2 0.92 9.2 0.1 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper Fib_alpha PF08702.5 OAI99487.1 - 0.67 10.0 4.1 1.8 8.6 2.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.3 OAI99487.1 - 0.69 9.8 9.9 0.14 12.0 3.9 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 OAI99487.1 - 0.8 10.4 6.1 4.1 8.1 2.3 2.3 1 1 1 2 2 2 0 Occludin homology domain BLOC1_2 PF10046.4 OAI99487.1 - 0.82 9.8 6.8 1.2 9.3 1.3 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin PF00804.20 OAI99487.1 - 1.1 9.5 7.6 5.8 7.1 5.3 2.1 1 1 0 1 1 1 0 Syntaxin DUF1664 PF07889.7 OAI99487.1 - 1.1 9.0 8.7 2.2 8.1 3.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2408 PF10303.4 OAI99487.1 - 1.9 8.5 6.1 1.1 9.3 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) V_ATPase_I PF01496.14 OAI99487.1 - 2.5 5.8 4.5 3.6 5.3 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 OAI99487.1 - 2.5 7.9 7.7 3.4 7.5 2.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spectrin PF00435.16 OAI99487.1 - 2.5 8.4 8.5 0.93 9.8 2.3 2.3 1 1 1 2 2 2 0 Spectrin repeat Med9 PF07544.8 OAI99487.1 - 2.8 7.7 8.7 6.7 6.5 0.2 2.8 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF972 PF06156.8 OAI99487.1 - 3.5 8.0 7.3 5 7.5 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V-SNARE PF05008.10 OAI99487.1 - 4.6 7.4 11.0 3.9 7.7 5.6 2.2 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Mnd1 PF03962.10 OAI99487.1 - 5.1 6.7 10.3 13 5.4 7.2 1.6 1 1 0 1 1 1 0 Mnd1 family HEAT PF02985.17 OAI99488.1 - 5.5e-24 82.0 6.5 0.00015 21.5 0.0 10.4 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 OAI99488.1 - 1e-17 63.9 7.4 1.9e-07 31.3 0.0 8.5 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 OAI99488.1 - 2.9e-16 59.5 14.0 7.6e-07 29.3 0.0 6.9 4 1 7 11 11 11 7 HEAT repeats IBN_N PF03810.14 OAI99488.1 - 7.5e-13 48.1 2.9 2.3e-10 40.2 0.2 3.6 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 OAI99488.1 - 0.00023 20.8 10.0 0.061 13.1 0.1 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 OAI99488.1 - 0.00071 19.2 0.2 4.8 6.7 0.0 4.0 3 1 1 4 4 4 1 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.2 OAI99488.1 - 0.00098 19.4 0.3 0.87 10.0 0.1 4.8 4 1 2 6 6 6 2 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 OAI99488.1 - 0.0018 18.1 2.7 1.6 8.6 0.0 3.6 3 1 0 4 4 4 2 Exportin 1-like protein MMS19_N PF14500.1 OAI99488.1 - 0.035 13.3 0.1 0.28 10.3 0.2 2.1 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HMG_box PF00505.14 OAI99489.1 - 2e-09 37.5 0.8 6.2e-05 23.1 0.3 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box Augurin PF15187.1 OAI99489.1 - 0.13 12.1 3.0 0.26 11.1 2.1 1.4 1 0 0 1 1 1 0 Oesophageal cancer-related gene 4 DSPc PF00782.15 OAI99490.1 - 1.8e-18 66.4 0.0 1.4e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAI99490.1 - 0.073 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Phage_integrase PF00589.17 OAI99491.1 - 0.069 12.8 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Phage integrase family Adaptin_N PF01602.15 OAI99494.1 - 9e-143 476.3 4.9 1.1e-142 476.1 3.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 OAI99494.1 - 2.3e-23 82.7 1.1 4e-23 81.9 0.8 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 OAI99494.1 - 2.2e-06 27.8 0.3 1.3 9.3 0.1 5.0 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 OAI99494.1 - 0.00052 19.8 1.4 11 6.4 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat RIX1 PF08167.7 OAI99494.1 - 0.0049 16.5 0.6 0.056 13.1 0.0 3.0 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TIP120 PF08623.5 OAI99494.1 - 0.0091 15.5 2.9 0.019 14.5 0.2 2.8 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.2 OAI99494.1 - 0.47 10.2 5.9 0.18 11.6 0.5 2.8 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Synaptobrevin PF00957.16 OAI99496.1 - 6.3e-27 93.0 0.1 1e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 OAI99496.1 - 9.8e-19 66.6 0.0 1.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SH3_1 PF00018.23 OAI99497.1 - 2.8e-14 52.2 0.2 5.7e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 OAI99497.1 - 2.3e-12 47.0 0.0 4.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 OAI99497.1 - 9.9e-12 44.2 0.0 2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAI99497.1 - 1.4e-09 37.6 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAI99497.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 OAI99497.1 - 2.9e-07 30.5 0.1 6.4e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 OAI99497.1 - 0.00028 20.8 0.1 0.00055 19.9 0.1 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_11 PF15413.1 OAI99497.1 - 0.22 11.8 0.2 0.51 10.6 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Iso_dh PF00180.15 OAI99498.1 - 1.9e-90 303.3 0.0 4.4e-90 302.1 0.0 1.5 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 OAI99498.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Gtr1_RagA PF04670.7 OAI99499.1 - 1e-82 276.8 0.0 1.4e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 OAI99499.1 - 8.5e-06 25.2 0.1 2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 OAI99499.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 OAI99499.1 - 0.0001 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 OAI99499.1 - 0.00019 21.8 0.0 0.00053 20.4 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAI99499.1 - 0.004 16.6 0.2 0.022 14.2 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 OAI99499.1 - 0.05 13.9 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CLTH PF10607.4 OAI99500.1 - 5.8e-05 22.8 0.0 0.00015 21.4 0.0 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAI99500.1 - 0.025 14.3 0.2 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 LisH Abhydrolase_6 PF12697.2 OAI99501.1 - 7.7e-09 35.7 0.4 9.2e-05 22.4 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99501.1 - 1.6e-08 34.4 0.1 2.6e-08 33.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAI99501.1 - 9.8e-08 31.7 0.1 1.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 OAI99501.1 - 6.6e-06 25.8 0.3 0.02 14.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAI99501.1 - 0.073 12.9 0.1 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase NmrA PF05368.8 OAI99502.1 - 5.9e-14 51.8 0.0 7.9e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAI99502.1 - 1.5e-08 34.8 0.0 2.6e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAI99502.1 - 0.0051 15.5 0.0 0.0072 15.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAI99502.1 - 0.0083 15.5 0.1 0.48 9.8 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAI99502.1 - 0.01 15.8 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Semialdhyde_dh PF01118.19 OAI99502.1 - 0.055 13.7 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.27 OAI99503.1 - 3.1e-52 172.6 23.4 8.1e-11 41.3 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAI99503.1 - 3.9e-05 22.1 0.0 0.00027 19.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain BBS2_Mid PF14783.1 OAI99503.1 - 0.011 15.4 0.0 0.18 11.6 0.0 2.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.7 OAI99503.1 - 0.057 13.1 0.1 24 4.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 OAI99503.1 - 0.25 9.4 1.1 10 4.1 0.1 2.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Helitron_like_N PF14214.1 OAI99507.1 - 6.3e-07 29.3 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_1 PF00078.22 OAI99508.1 - 3.1e-23 82.2 0.0 5.9e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MoeA_C PF03454.10 OAI99508.1 - 0.00054 19.8 1.3 0.47 10.4 0.0 3.3 3 0 0 3 3 3 2 MoeA C-terminal region (domain IV) Exo_endo_phos_2 PF14529.1 OAI99508.1 - 0.091 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase AMPKBI PF04739.10 OAI99508.1 - 0.11 12.4 0.2 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Bunya_RdRp PF04196.7 OAI99508.1 - 1.8 6.4 0.0 2.6 5.9 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Pkinase PF00069.20 OAI99514.1 - 0.0011 18.2 0.0 0.0021 17.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 OAI99517.1 - 8e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99517.1 - 0.0091 15.0 0.0 0.47 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAI99519.1 - 3.1e-10 39.6 0.0 7.7e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99519.1 - 0.00014 21.0 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAI99521.1 - 7.8e-11 41.6 0.1 9.1e-11 41.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99521.1 - 1.7e-06 27.3 0.1 2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AD PF09793.4 OAI99521.1 - 0.018 14.8 0.1 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Anticodon-binding domain Pkinase PF00069.20 OAI99522.1 - 8.4e-12 44.7 0.0 2.9e-11 43.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99522.1 - 0.0029 16.7 0.0 0.078 12.0 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase MOSC_N PF03476.11 OAI99525.1 - 1.4e-21 76.4 0.0 2.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAI99525.1 - 3.6e-11 42.6 1.0 9e-05 21.9 0.0 2.8 2 1 0 2 2 2 2 MOSC domain 7tm_7 PF08395.7 OAI99526.1 - 0.075 12.0 0.8 0.12 11.3 0.6 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF3353 PF11833.3 OAI99526.1 - 0.14 11.6 0.5 0.34 10.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DnaJ PF00226.26 OAI99527.1 - 2.4e-18 65.6 0.1 4.1e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.15 OAI99527.1 - 4e-07 29.7 0.0 1.2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 DHH family adh_short PF00106.20 OAI99528.1 - 3.4e-16 59.6 1.3 5.4e-16 58.9 0.9 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI99528.1 - 3.2e-07 30.2 0.4 6.9e-07 29.1 0.3 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAI99528.1 - 7.8e-05 22.5 0.0 0.0002 21.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI99528.1 - 0.00063 19.7 0.2 0.0025 17.8 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 OAI99528.1 - 0.0012 19.2 0.4 0.042 14.2 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 OAI99528.1 - 0.027 13.7 0.1 0.36 10.0 0.0 2.2 2 1 0 2 2 2 0 NmrA-like family DUF1598 PF07643.6 OAI99528.1 - 0.06 13.3 0.0 0.22 11.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1598) 3HCDH_N PF02737.13 OAI99528.1 - 0.062 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 OAI99530.1 - 6.5e-08 32.7 0.3 1e-07 32.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99530.1 - 1e-06 28.5 0.1 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAI99530.1 - 0.0015 18.2 0.1 0.0039 16.8 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.13 OAI99530.1 - 0.0048 16.2 0.0 0.056 12.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.9 OAI99530.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 OAI99530.1 - 0.054 13.0 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 OAI99530.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 OAI99530.1 - 0.19 10.6 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase bZIP_1 PF00170.16 OAI99531.1 - 7.8e-06 25.7 8.5 2e-05 24.4 5.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAI99531.1 - 0.01 15.6 7.0 0.01 15.6 4.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper Herpes_env PF01673.13 OAI99531.1 - 0.036 12.6 3.3 0.065 11.7 2.3 1.5 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein WD40 PF00400.27 OAI99532.1 - 1.1e-46 155.0 16.9 4.1e-09 35.9 0.1 9.9 10 0 0 10 10 10 8 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAI99532.1 - 2.5e-05 23.9 0.1 0.036 13.8 0.0 4.4 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 OAI99532.1 - 0.00041 18.6 0.4 0.0041 15.3 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAI99532.1 - 0.00064 18.5 0.0 0.69 8.5 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 OAI99532.1 - 0.015 13.5 0.0 0.033 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 OAI99532.1 - 0.064 11.0 0.0 1.4 6.6 0.0 2.5 3 0 0 3 3 3 0 IKI3 family PQQ_3 PF13570.1 OAI99532.1 - 0.08 13.2 21.2 0.62 10.4 0.1 6.4 6 1 0 6 6 6 0 PQQ-like domain PQQ PF01011.16 OAI99532.1 - 0.67 9.5 4.4 2.2 7.9 0.1 3.9 5 0 0 5 5 5 0 PQQ enzyme repeat Myb_DNA-bind_5 PF13873.1 OAI99533.1 - 0.1 12.5 8.0 0.19 11.6 0.2 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.1 OAI99534.1 - 3.5e-22 78.6 0.0 5.7e-21 74.7 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI99534.1 - 0.00098 18.7 0.1 0.55 9.7 0.0 2.1 2 0 0 2 2 2 2 Transposase DDE domain Aminotran_5 PF00266.14 OAI99537.1 - 1.2e-32 113.0 0.1 1.9e-26 92.7 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAI99537.1 - 1.6e-06 26.7 0.0 8e-06 24.3 0.0 2.1 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme AA_permease_2 PF13520.1 OAI99538.1 - 6.7e-50 169.8 37.0 1.8e-49 168.4 25.7 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAI99538.1 - 5.5e-15 54.6 28.8 5.5e-15 54.6 19.9 1.9 2 0 0 2 2 2 1 Amino acid permease Pterin_bind PF00809.17 OAI99539.1 - 1.7e-49 168.0 0.3 5.7e-49 166.3 0.2 1.9 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 OAI99539.1 - 4.3e-27 94.3 0.0 3.1e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 OAI99539.1 - 8.9e-18 64.4 0.0 2.3e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase DUF2076 PF09849.4 OAI99539.1 - 6.4 6.7 6.4 0.41 10.6 0.7 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Cellulase PF00150.13 OAI99541.1 - 3.6e-29 101.8 0.2 4.8e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF500 PF04366.7 OAI99542.1 - 6e-36 122.6 0.4 1.3e-35 121.5 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 OAI99542.1 - 7.2e-13 47.9 0.0 1.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAI99542.1 - 1.8e-12 46.4 0.0 2.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAI99542.1 - 2e-10 39.9 0.0 4.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UbiA PF01040.13 OAI99543.1 - 2.2e-33 115.5 17.5 3.8e-33 114.7 12.1 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_integrase PF00589.17 OAI99545.1 - 1.8e-05 24.4 0.0 5.3e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 OAI99545.1 - 0.01 15.5 0.1 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like RAP1 PF07218.6 OAI99545.1 - 0.12 10.4 17.9 0.19 9.7 12.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_L16 PF00252.13 OAI99548.1 - 9.3e-40 135.4 0.6 1.2e-39 135.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SNARE PF05739.14 OAI99549.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 SNARE domain rve PF00665.21 OAI99550.1 - 3.3e-18 65.9 0.0 8.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAI99550.1 - 6.9e-13 48.4 0.0 1.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAI99550.1 - 0.0012 18.7 3.1 0.0012 18.7 2.1 2.1 3 0 0 3 3 3 1 Zinc knuckle rve_3 PF13683.1 OAI99550.1 - 0.0016 17.8 0.1 0.0048 16.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99550.1 - 0.0098 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_2 PF13696.1 OAI99550.1 - 0.015 14.8 0.6 0.029 13.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 OAI99550.1 - 0.061 13.1 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_4 PF14392.1 OAI99550.1 - 0.19 11.3 3.5 3 7.5 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle MULE PF10551.4 OAI99551.1 - 2.4e-18 66.0 0.0 1e-17 64.0 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAI99551.1 - 4.2e-09 35.4 0.3 6.5e-09 34.8 0.2 1.2 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 OAI99551.1 - 0.00019 20.8 5.9 0.001 18.5 0.8 2.5 2 0 0 2 2 2 2 SWIM zinc finger LpxB PF02684.10 OAI99551.1 - 0.048 12.2 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Abhydrolase_5 PF12695.2 OAI99552.1 - 4.6e-06 26.4 0.0 9.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 OAI99552.1 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 OAI99552.1 - 0.00023 21.1 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAI99552.1 - 0.0012 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 OAI99552.1 - 0.0013 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 OAI99552.1 - 0.016 15.4 0.0 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain DUF915 PF06028.6 OAI99552.1 - 0.18 10.9 0.0 0.46 9.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) TFIIF_beta PF02270.10 OAI99553.1 - 1.2e-43 149.9 0.0 1.5e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 OAI99553.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 IS66 C-terminal element LSM PF01423.17 OAI99554.1 - 5.7e-21 73.8 0.2 6.6e-21 73.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain JAB PF01398.16 OAI99555.1 - 1.1e-13 50.8 0.0 8.6e-13 48.0 0.0 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAI99555.1 - 3.1e-09 36.9 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function HisKA PF00512.20 OAI99555.1 - 0.02 14.8 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain INCA1 PF15142.1 OAI99556.1 - 0.03 14.1 3.4 0.77 9.5 0.2 2.6 2 0 0 2 2 2 0 INCA1 PX PF00787.19 OAI99557.1 - 3.3e-12 46.2 0.0 5.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 OAI99557.1 - 2.5e-09 36.7 3.0 3.8e-09 36.0 2.1 1.3 1 0 0 1 1 1 1 SNARE domain SlyX PF04102.7 OAI99557.1 - 1.5 9.2 4.8 15 6.0 0.3 2.7 1 1 1 2 2 2 0 SlyX SUR7 PF06687.7 OAI99558.1 - 2.3e-18 66.5 14.2 3e-18 66.1 9.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAI99558.1 - 9.7 5.8 13.5 34 4.0 9.3 2.0 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Bap31 PF05529.7 OAI99559.1 - 5.1e-54 182.6 7.8 6.7e-54 182.2 5.4 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like ADIP PF11559.3 OAI99559.1 - 8 6.3 11.3 1.7 8.5 3.6 2.3 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding NAD_binding_10 PF13460.1 OAI99561.1 - 0.0015 18.5 0.0 0.018 15.0 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding DivIC PF04977.10 OAI99566.1 - 0.019 14.4 1.0 0.032 13.7 0.2 1.7 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 OAI99566.1 - 0.033 13.9 0.8 0.045 13.4 0.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2130 PF09903.4 OAI99566.1 - 0.045 12.5 0.0 0.061 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) IncA PF04156.9 OAI99566.1 - 0.059 12.9 0.0 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 IncA protein SlyX PF04102.7 OAI99566.1 - 0.12 12.7 0.4 0.2 12.0 0.3 1.3 1 0 0 1 1 1 0 SlyX RVT_1 PF00078.22 OAI99567.1 - 6.5e-20 71.4 0.0 1.2e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99567.1 - 7.1e-15 55.1 0.0 9.8e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain DDE_3 PF13358.1 OAI99567.1 - 0.03 14.0 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease Asp_protease_2 PF13650.1 OAI99568.1 - 1.2e-05 25.7 0.1 5.2e-05 23.6 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99568.1 - 0.0027 17.4 0.2 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF641 PF04859.7 OAI99568.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) MscS_porin PF12795.2 OAI99568.1 - 0.3 10.3 2.4 0.47 9.7 1.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Dimer_Tnp_hAT PF05699.9 OAI99570.1 - 1.6e-08 34.0 0.0 2.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region GATA PF00320.22 OAI99572.1 - 4.2e-05 22.8 1.9 7.7e-05 21.9 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF3323 PF11796.3 OAI99573.1 - 0.011 15.0 0.1 0.011 15.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) MxiH PF09392.5 OAI99573.1 - 1.5 9.4 8.4 4.1e+02 1.6 5.8 3.8 1 1 0 1 1 1 0 Type III secretion needle MxiH like Pcc1 PF09341.5 OAI99574.1 - 2.5e-20 72.2 0.7 3.2e-20 71.9 0.5 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PPC PF04151.10 OAI99574.1 - 0.24 12.3 1.0 0.99 10.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain WD40 PF00400.27 OAI99575.1 - 4.8e-69 225.9 10.2 6.8e-11 41.6 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 OAI99575.1 - 2.3e-21 75.7 3.7 2.3e-21 75.7 2.6 2.4 2 0 0 2 2 1 1 Tup N-terminal eIF2A PF08662.6 OAI99575.1 - 9.9e-05 22.1 0.0 0.1 12.3 0.0 3.7 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 OAI99575.1 - 0.0039 16.8 1.1 35 4.2 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PRP38_assoc PF12871.2 OAI99575.1 - 0.0088 16.5 37.3 0.0088 16.5 25.8 3.5 3 1 1 4 4 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Nup160 PF11715.3 OAI99575.1 - 0.015 13.4 1.3 3.5 5.6 0.0 3.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAI99575.1 - 0.058 12.1 0.1 1.4 7.5 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 OAI99575.1 - 0.14 11.2 0.3 8.9 5.3 0.0 3.4 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 OAI99575.1 - 0.2 11.0 3.4 16 4.9 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature IL8 PF00048.15 OAI99575.1 - 0.25 11.3 1.1 0.75 9.8 0.8 1.8 1 1 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like CAF-1_p150 PF11600.3 OAI99575.1 - 0.26 10.6 34.6 0.51 9.6 24.0 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.8 OAI99575.1 - 3.1 7.5 27.8 6 6.6 19.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1768 PF08719.6 OAI99580.1 - 1.9e-22 79.6 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAI99581.1 - 5.4e-28 97.7 0.0 1.2e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) BTB PF00651.26 OAI99582.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF1768 PF08719.6 OAI99585.1 - 2.2e-24 85.9 0.0 3.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.6 OAI99586.1 - 8.9e-26 90.5 0.3 1.1e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF285 PF03382.9 OAI99586.1 - 0.013 15.0 1.5 0.02 14.4 1.0 1.2 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 RepB-RCR_reg PF10723.4 OAI99586.1 - 0.068 12.9 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 Replication regulatory protein RepB LIM PF00412.17 OAI99586.1 - 0.11 12.5 2.6 0.35 10.9 1.7 1.8 2 0 0 2 2 2 0 LIM domain RRM_5 PF13893.1 OAI99586.1 - 0.12 12.1 0.1 1.3 8.9 0.1 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAI99586.1 - 0.15 11.6 0.2 0.36 10.4 0.1 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 OAI99587.1 - 1.7e-24 86.6 0.0 2.5e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAI99587.1 - 3.5e-06 26.9 0.0 6.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAI99587.1 - 3.9e-06 26.6 0.0 6.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAI99587.1 - 0.0013 18.7 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Sod_Fe_C PF02777.13 OAI99588.1 - 1.5e-14 53.6 0.2 5.6e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAI99588.1 - 0.0021 18.2 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF1768 PF08719.6 OAI99589.1 - 2e-24 86.1 0.0 3.4e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PQ-loop PF04193.9 OAI99590.1 - 6.7e-07 28.7 0.1 9.5e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 PQ loop repeat DUF3505 PF12013.3 OAI99591.1 - 0.035 14.3 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Glyco_hydro_92 PF07971.7 OAI99592.1 - 1.9e-106 356.7 0.0 2.7e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pkinase PF00069.20 OAI99595.1 - 1.3e-10 40.8 0.0 2.9e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99595.1 - 1.4e-05 24.2 0.0 2.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase zf-nanos PF05741.8 OAI99596.1 - 0.014 15.3 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 Nanos RNA binding domain DUF2703 PF10865.3 OAI99596.1 - 0.14 12.1 0.4 0.96 9.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Zn_clus PF00172.13 OAI99597.1 - 3.3e-07 30.0 9.1 5.7e-07 29.3 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1777 PF08648.7 OAI99597.1 - 4.4e-06 26.5 12.3 4.4e-06 26.5 8.5 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1777) Fungal_trans PF04082.13 OAI99597.1 - 0.00026 19.9 0.3 0.039 12.8 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 OAI99598.1 - 9.1e-28 96.9 26.5 9.1e-28 96.9 18.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 OAI99598.1 - 0.0019 18.1 1.8 0.52 10.3 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) ERG4_ERG24 PF01222.12 OAI99599.1 - 1.8e-143 478.2 4.3 2e-143 478.0 3.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 OAI99599.1 - 6e-05 23.1 0.3 0.00029 20.9 0.0 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAI99599.1 - 7.7e-05 22.0 0.1 7.7e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) ICMT PF04140.9 OAI99599.1 - 0.0052 16.9 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Endosulfine PF04667.12 OAI99600.1 - 4.4e-18 65.0 0.0 9e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region SOG2 PF10428.4 OAI99600.1 - 4.4 5.8 7.8 4.8 5.7 5.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Phage_Gp23 PF10669.4 OAI99601.1 - 0.11 12.6 3.2 0.26 11.3 0.6 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DDE_Tnp_4 PF13359.1 OAI99602.1 - 1.3e-21 76.8 0.0 1.9e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAI99602.1 - 0.0013 18.2 5.0 0.0016 18.0 0.1 2.7 2 1 0 2 2 2 1 Transposase DDE domain Retrotrans_gag PF03732.12 OAI99604.1 - 0.28 11.2 0.2 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 OAI99605.1 - 5.3e-20 71.7 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99605.1 - 1.3e-14 54.3 0.0 2.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99605.1 - 0.013 15.9 0.1 0.054 14.0 0.1 2.1 2 0 0 2 2 2 0 Aspartyl protease Sec2p PF06428.6 OAI99611.1 - 0.015 15.1 0.8 0.027 14.3 0.5 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PAT1 PF09770.4 OAI99612.1 - 0.038 12.2 6.6 0.05 11.8 4.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Helicase_C PF00271.26 OAI99617.1 - 0.00086 19.1 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 OAI99619.1 - 5.9e-43 146.8 0.0 2.8e-41 141.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99619.1 - 1.9e-20 73.0 0.0 1.7e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAI99619.1 - 8.6e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAI99619.1 - 0.0061 16.3 0.2 0.033 13.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 OAI99619.1 - 0.041 12.9 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BUD22 PF09073.5 OAI99620.1 - 0.071 12.1 7.2 0.21 10.6 5.0 1.7 1 1 0 1 1 1 0 BUD22 NPBW PF15180.1 OAI99620.1 - 0.12 12.0 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Neuropeptides B and W Nucleoplasmin PF03066.10 OAI99621.1 - 0.033 13.7 3.5 0.049 13.1 2.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin zf-Dof PF02701.10 OAI99622.1 - 0.061 13.2 0.2 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Dof domain, zinc finger NARP1 PF12569.3 OAI99622.1 - 5.5 5.6 16.6 12 4.4 11.5 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MULE PF10551.4 OAI99628.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAI99628.1 - 0.36 10.3 5.3 5 6.6 0.6 2.6 2 0 0 2 2 2 0 SWIM zinc finger RVT_1 PF00078.22 OAI99631.1 - 2.3e-18 66.3 0.0 4.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99631.1 - 1.3e-14 54.3 0.0 2.7e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99631.1 - 0.00087 19.7 0.1 0.003 18.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99631.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.8 OAI99631.1 - 0.24 9.7 0.0 0.41 9.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein SelP_N PF04592.9 OAI99634.1 - 0.83 8.9 12.7 0.99 8.7 8.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PRCC PF10253.4 OAI99634.1 - 0.99 10.0 9.0 1.2 9.7 6.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MCPVI PF02993.9 OAI99634.1 - 2.3 8.2 9.2 2.7 8.0 6.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DUF2360 PF10152.4 OAI99634.1 - 9 6.5 10.2 9.6 6.4 7.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF904 PF06005.7 OAI99640.1 - 0.66 10.3 4.0 0.79 10.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Amidase02_C PF12123.3 OAI99641.1 - 0.12 12.0 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DNA_pol_E_B PF04042.11 OAI99644.1 - 5.7e-28 97.6 0.0 1.2e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B VID27 PF08553.5 OAI99644.1 - 0.25 9.5 5.1 0.43 8.7 3.5 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein TEX19 PF15553.1 OAI99644.1 - 1.3 8.8 4.6 2.5 7.9 0.2 2.2 2 0 0 2 2 2 0 Testis-expressed protein 19 BNIP2 PF12496.3 OAI99644.1 - 2.9 8.0 9.2 0.28 11.3 1.3 2.3 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Sugar_tr PF00083.19 OAI99645.1 - 2.6e-64 217.4 2.3 3.4e-64 217.0 1.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAI99645.1 - 7.5e-21 74.2 4.8 9.3e-21 73.9 3.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COX6B PF02297.12 OAI99646.1 - 1.2e-19 70.0 8.7 1.5e-19 69.8 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 OAI99646.1 - 0.081 12.8 0.4 0.25 11.3 0.3 1.9 1 1 0 1 1 1 0 CHCH domain UCR_hinge PF02320.11 OAI99646.1 - 0.14 12.1 0.5 0.14 12.1 0.4 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 OAI99646.1 - 0.98 9.3 8.0 3 7.7 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) ACBP PF00887.14 OAI99647.1 - 5e-32 109.4 0.2 6.1e-32 109.1 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tox-REase-5 PF15648.1 OAI99647.1 - 0.039 14.2 0.2 0.044 14.0 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 Involucrin_N PF10583.4 OAI99648.1 - 6.1 7.2 5.7 38 4.6 0.0 3.5 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus KH_1 PF00013.24 OAI99649.1 - 2.8e-43 145.3 9.2 9.2e-17 60.4 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAI99649.1 - 2.2e-31 106.9 14.6 2.3e-10 39.8 1.4 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAI99649.1 - 3.1e-15 55.4 6.7 2.4e-05 23.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 OAI99649.1 - 2.4e-06 27.0 1.9 0.59 9.8 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 OAI99649.1 - 0.037 13.8 6.8 1.4 8.7 0.1 3.5 3 1 0 3 3 3 0 NusA-like KH domain COX16 PF14138.1 OAI99650.1 - 7.6e-26 90.0 0.1 1.6e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.8 OAI99650.1 - 1.3e-24 85.9 0.0 4.1e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 Erv1 / Alr family zf-CHY PF05495.7 OAI99651.1 - 3.1e-15 56.0 12.2 4.5e-15 55.5 8.4 1.2 1 0 0 1 1 1 1 CHY zinc finger PhnA_Zn_Ribbon PF08274.7 OAI99651.1 - 0.039 13.7 1.2 1 9.1 0.2 2.8 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.5 OAI99651.1 - 0.12 12.3 8.9 0.16 11.9 0.8 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Evr1_Alr PF04777.8 OAI99651.1 - 0.13 12.1 1.4 0.27 11.1 1.0 1.6 1 0 0 1 1 1 0 Erv1 / Alr family TF_Zn_Ribbon PF08271.7 OAI99651.1 - 0.22 10.8 2.5 0.91 8.8 0.6 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 OAI99651.1 - 0.33 10.6 7.0 0.064 12.9 2.1 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Tmemb_55A PF09788.4 OAI99651.1 - 0.34 9.9 5.4 0.43 9.6 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A DZR PF12773.2 OAI99651.1 - 0.76 9.6 8.3 0.45 10.3 3.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.14 OAI99651.1 - 2.2 8.0 7.7 0.34 10.5 0.6 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 OAI99651.1 - 3.3 7.5 10.7 23 4.8 5.5 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sugar_tr PF00083.19 OAI99652.1 - 8.8e-84 281.6 15.2 9.4e-70 235.4 3.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAI99652.1 - 9.1e-23 80.5 14.2 9.1e-23 80.5 9.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2746 PF10874.3 OAI99653.1 - 0.099 12.8 4.6 0.24 11.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Trp_syntA PF00290.15 OAI99654.1 - 1.9e-80 269.1 0.0 3.6e-80 268.2 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 OAI99654.1 - 6.5e-47 160.2 0.5 6.5e-47 160.2 0.3 1.9 2 1 1 3 3 3 1 Pyridoxal-phosphate dependent enzyme PA PF02225.17 OAI99654.1 - 0.0021 17.7 1.8 0.056 13.1 0.1 2.5 2 0 0 2 2 2 1 PA domain His_biosynth PF00977.16 OAI99654.1 - 0.0023 17.2 0.1 0.0093 15.2 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein DFP PF04127.10 OAI99654.1 - 0.029 13.9 0.7 0.31 10.6 0.1 2.6 2 1 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein PTR2 PF00854.16 OAI99655.1 - 1e-38 133.1 16.7 2.3e-22 79.3 5.4 2.5 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 OAI99655.1 - 2.6e-07 29.6 34.6 1.7e-05 23.7 24.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily EHN PF06441.7 OAI99658.1 - 8.3e-28 96.5 0.0 1.9e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 OAI99658.1 - 1.4e-08 34.9 3.4 1.5e-07 31.5 0.8 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI99658.1 - 0.0055 16.2 0.2 0.036 13.6 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Mo25 PF08569.6 OAI99659.1 - 3.2e-118 394.6 0.5 3.3e-115 384.7 0.4 2.6 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 OAI99659.1 - 0.014 15.6 0.0 0.27 11.5 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats RepA_N PF06970.6 OAI99659.1 - 0.37 10.5 3.4 0.19 11.5 0.6 1.8 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Methyltransf_2 PF00891.13 OAI99660.1 - 5.2e-29 101.1 0.0 7.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 OAI99660.1 - 0.0028 17.2 0.5 3.1 7.5 0.0 2.7 2 0 0 2 2 2 2 MarR family RPA_C PF08784.6 OAI99660.1 - 0.015 15.6 0.0 0.04 14.3 0.0 1.9 1 1 0 1 1 1 0 Replication protein A C terminal Methyltransf_12 PF08242.7 OAI99660.1 - 0.049 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain M20_dimer PF07687.9 OAI99661.1 - 1.9e-08 34.0 0.5 3.8e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 OAI99661.1 - 5.1e-08 32.6 0.4 8.2e-08 31.9 0.2 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M43 PF05572.8 OAI99663.1 - 2.8e-23 82.2 0.8 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 OAI99663.1 - 0.0009 19.2 7.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 2 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAI99663.1 - 0.001 18.6 1.5 1.2 8.6 0.2 2.7 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAI99663.1 - 0.0015 19.0 4.8 0.45 11.0 0.0 3.3 3 0 0 3 3 3 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 OAI99663.1 - 0.012 15.3 0.9 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M54 Reprolysin_2 PF13574.1 OAI99663.1 - 0.031 14.3 8.7 0.93 9.5 0.1 3.3 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF1954 PF09199.5 OAI99663.1 - 0.049 13.8 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1954) Metallopep PF12044.3 OAI99663.1 - 0.071 11.5 4.7 1.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Putative peptidase family PCIF1_WW PF12237.3 OAI99663.1 - 0.073 12.3 0.5 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain Cytidylate_kin2 PF13189.1 OAI99663.1 - 0.29 11.0 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Peptidase_M66 PF10462.4 OAI99663.1 - 10 4.9 10.0 9.4 5.0 1.0 2.4 2 0 0 2 2 2 0 Peptidase M66 AATase PF07247.7 OAI99669.1 - 0.02 13.4 0.0 0.043 12.3 0.0 1.4 1 1 0 1 1 1 0 Alcohol acetyltransferase LRR_6 PF13516.1 OAI99670.1 - 2.9e-23 79.2 21.9 0.52 10.5 0.0 18.5 22 0 0 22 22 22 3 Leucine Rich repeat LRR_4 PF12799.2 OAI99670.1 - 7.6e-15 54.1 25.4 0.13 11.9 0.0 11.1 12 0 0 12 12 12 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAI99670.1 - 2.1e-08 33.8 39.1 2.1 8.1 0.3 11.5 6 3 4 10 10 10 5 Leucine rich repeat VWA PF00092.23 OAI99670.1 - 0.0009 19.0 6.7 0.019 14.6 0.1 4.7 4 1 0 4 4 4 1 von Willebrand factor type A domain Rap1_C PF11626.3 OAI99670.1 - 0.001 18.9 3.4 0.54 10.1 0.1 3.9 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ACT PF01842.20 OAI99670.1 - 0.0046 16.4 0.6 53 3.4 0.0 4.9 4 0 0 4 4 4 0 ACT domain NifU PF01106.12 OAI99670.1 - 0.0087 15.8 2.7 20 5.0 0.0 4.1 4 0 0 4 4 4 0 NifU-like domain LRR_1 PF00560.28 OAI99670.1 - 0.023 14.6 21.5 86 3.7 0.0 12.6 15 3 2 17 17 17 0 Leucine Rich Repeat Glyco_transf_7C PF02709.9 OAI99670.1 - 5.2 6.6 6.7 18 4.8 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain of galactosyltransferase LGT PF01790.13 OAI99670.1 - 8 5.3 2.4 1.5e+02 1.1 0.0 2.8 3 0 0 3 3 3 0 Prolipoprotein diacylglyceryl transferase WD40 PF00400.27 OAI99671.1 - 8.6e-33 111.0 15.4 6.9e-09 35.2 0.1 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 OAI99671.1 - 0.01 15.5 0.3 0.31 10.7 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RXT2_N PF08595.6 OAI99671.1 - 0.072 12.8 4.7 0.12 12.1 3.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4613 PF15390.1 OAI99671.1 - 0.13 10.3 0.3 0.19 9.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) RVT_1 PF00078.22 OAI99672.1 - 3.2e-29 101.8 0.0 5e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAI99672.1 - 5e-14 52.7 0.0 1.1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAI99672.1 - 3.9e-09 36.1 0.0 1.1e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAI99672.1 - 1.8e-08 34.6 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 OAI99672.1 - 0.034 13.9 0.6 0.086 12.6 0.1 1.9 2 0 0 2 2 2 0 Reverse transcriptase-like DUF3641 PF12345.3 OAI99673.1 - 0.004 16.9 0.4 0.0046 16.7 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Shisa PF13908.1 OAI99674.1 - 1.7 8.8 9.8 0.26 11.4 0.2 3.2 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator ApoO PF09769.4 OAI99675.1 - 0.048 13.3 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein O DUF3481 PF11980.3 OAI99675.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3481) Tetraspannin PF00335.15 OAI99675.1 - 0.33 10.2 15.8 0.049 12.8 7.8 1.8 1 1 1 2 2 2 0 Tetraspanin family EphA2_TM PF14575.1 OAI99675.1 - 1.2 9.5 3.1 7.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain YjbE PF11106.3 OAI99675.1 - 5 7.1 16.7 0.12 12.3 6.3 2.1 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE Diphthamide_syn PF01866.12 OAI99679.1 - 9e-49 166.3 0.0 5.7e-23 81.6 0.0 3.7 3 1 0 3 3 3 3 Putative diphthamide synthesis protein SNARE PF05739.14 OAI99680.1 - 8e-17 60.6 5.4 1.2e-16 60.0 2.9 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 OAI99680.1 - 5.2e-13 49.0 3.0 1.9e-11 44.0 0.1 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 OAI99680.1 - 0.0077 15.7 6.3 0.03 13.8 1.5 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Lebercilin PF15619.1 OAI99680.1 - 0.03 13.7 0.6 0.03 13.7 0.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.17 OAI99680.1 - 0.046 13.7 1.8 0.22 11.5 0.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DNA_repr_REX1B PF14966.1 OAI99680.1 - 0.057 13.8 0.8 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 DNA repair REX1-B SlyX PF04102.7 OAI99680.1 - 0.4 11.0 6.8 6.2 7.2 0.2 3.4 2 1 1 3 3 3 0 SlyX DUF3708 PF12501.3 OAI99680.1 - 1.7 8.4 6.4 14 5.5 0.1 2.4 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Rotamase PF00639.16 OAI99681.1 - 1.1e-20 74.1 0.0 2.4e-20 73.0 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 OAI99681.1 - 1.8e-16 60.4 0.0 3.6e-16 59.4 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 OAI99681.1 - 1.6e-07 31.0 0.1 1.6e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 OAI99681.1 - 0.022 15.4 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Yae1_N PF09811.4 OAI99682.1 - 1.3e-11 43.8 2.6 1.3e-11 43.8 1.8 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal PmrD PF11183.3 OAI99682.1 - 0.033 14.0 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Peptidase_M24 PF00557.19 OAI99684.1 - 1.6e-42 145.4 0.0 2.4e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 CDC45 PF02724.9 OAI99684.1 - 0.29 9.1 4.4 0.4 8.6 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 OAI99684.1 - 0.33 9.9 5.7 0.61 9.0 3.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cnd2 PF05786.9 OAI99684.1 - 0.75 8.2 8.3 1.1 7.6 5.8 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.7 OAI99684.1 - 2.2 6.1 6.3 3.4 5.4 4.3 1.2 1 0 0 1 1 1 0 Nop14-like family PAP_assoc PF03828.14 OAI99685.1 - 2.8e-15 56.0 0.0 7.7e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAI99685.1 - 5.7e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DEAD PF00270.24 OAI99686.1 - 8.7e-45 152.2 0.0 2.4e-44 150.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI99686.1 - 1.1e-23 82.8 0.0 5.3e-23 80.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAI99686.1 - 0.01 14.6 0.0 0.03 13.1 0.0 1.5 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF4246 PF14033.1 OAI99687.1 - 1.8e-122 409.5 4.7 2.1e-122 409.3 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.4 OAI99687.1 - 0.00037 19.9 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_5 PF13759.1 OAI99687.1 - 0.0058 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase zf-UBR PF02207.15 OAI99688.1 - 1.9e-14 53.0 14.7 1.9e-14 53.0 10.2 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 OAI99688.1 - 6e-08 32.3 0.2 2e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 OAI99688.1 - 0.051 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL WD40 PF00400.27 OAI99689.1 - 2.7e-09 36.5 0.0 0.38 10.7 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2415 PF10313.4 OAI99689.1 - 0.1 12.2 0.0 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Nop14 PF04147.7 OAI99689.1 - 0.45 8.3 18.6 0.65 7.8 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAI99689.1 - 1 8.5 15.6 1.4 8.0 10.8 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.7 OAI99689.1 - 6 6.0 9.6 10 5.2 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAI99689.1 - 6 4.7 11.2 8.6 4.2 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein UCR_Fe-S_N PF10399.4 OAI99694.1 - 0.14 11.3 0.3 0.33 10.1 0.2 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Brr6_like_C_C PF10104.4 OAI99695.1 - 0.034 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FliG_N PF14842.1 OAI99695.1 - 0.034 14.2 0.3 0.052 13.6 0.2 1.2 1 0 0 1 1 1 0 FliG N-terminal domain TMEM107 PF14995.1 OAI99695.1 - 0.11 12.6 1.5 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein PAF-AH_p_II PF03403.8 OAI99696.1 - 4.6e-39 133.7 0.0 3e-20 71.8 0.0 3.9 3 2 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 OAI99696.1 - 3.1e-09 36.7 0.3 4.3e-08 33.0 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI99696.1 - 0.017 14.9 2.3 0.12 12.1 1.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAI99696.1 - 0.11 12.3 0.1 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Chlorophyllase2 PF12740.2 OAI99696.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme HSP70 PF00012.15 OAI99697.1 - 2.2e-261 868.0 12.0 2.5e-261 867.8 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAI99697.1 - 1.5e-16 59.8 1.3 6.9e-14 51.1 0.2 2.5 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 OAI99697.1 - 2e-05 24.3 2.2 0.18 11.6 0.2 3.4 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 OAI99697.1 - 0.0028 17.2 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Seryl_tRNA_N PF02403.17 OAI99697.1 - 0.0043 17.0 6.8 0.017 15.1 4.7 2.0 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Hydantoinase_A PF01968.13 OAI99697.1 - 0.039 13.0 7.0 0.32 10.0 0.1 3.2 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase RVT_1 PF00078.22 OAI99698.1 - 1.7e-18 66.7 0.0 3.2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99698.1 - 4.5e-14 52.5 0.0 9.7e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAI99698.1 - 0.0004 20.8 0.1 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAI99698.1 - 0.027 14.3 0.1 0.11 12.3 0.1 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease C1q PF00386.16 OAI99698.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 C1q domain RVP PF00077.15 OAI99698.1 - 0.091 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Brr6_like_C_C PF10104.4 OAI99701.1 - 0.034 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FliG_N PF14842.1 OAI99701.1 - 0.034 14.2 0.3 0.052 13.6 0.2 1.2 1 0 0 1 1 1 0 FliG N-terminal domain TMEM107 PF14995.1 OAI99701.1 - 0.11 12.6 1.5 0.99 9.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein Cyclin_N PF00134.18 OAI99705.1 - 4.2e-10 39.2 0.0 2.1e-07 30.5 0.0 2.9 3 0 0 3 3 3 2 Cyclin, N-terminal domain RecO_C PF02565.10 OAI99705.1 - 0.097 12.5 0.2 2.1 8.2 0.0 2.3 2 1 0 2 2 2 0 Recombination protein O C terminal Mis12 PF05859.7 OAI99706.1 - 1.5e-17 63.7 0.2 8.3e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Mis12 protein Myb_DNA-binding PF00249.26 OAI99707.1 - 1.3e-13 50.7 0.0 1.2e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAI99707.1 - 2.4e-11 43.5 0.0 2.2e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.5 OAI99707.1 - 0.0015 18.6 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 2 Ribosome biogenesis protein Nop16 Peptidase_S10 PF00450.17 OAI99708.1 - 9.4e-96 321.4 0.0 1.2e-95 321.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.8 OAI99709.1 - 6.8e-07 29.0 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAI99709.1 - 4.9e-05 23.1 0.0 9e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAI99709.1 - 0.00061 19.7 4.8 0.00088 19.2 3.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 OAI99709.1 - 0.0069 15.8 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) EI24 PF07264.6 OAI99710.1 - 5.9e-23 81.4 13.9 9.2e-23 80.8 9.6 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 4HBT_2 PF13279.1 OAI99711.1 - 8e-05 23.0 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily SOG2 PF10428.4 OAI99712.1 - 5.8 5.4 6.8 6.8 5.2 4.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein 6PF2K PF01591.13 OAI99714.1 - 3.1e-69 232.4 0.0 4.4e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAI99714.1 - 1.2e-30 106.7 0.0 2.1e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAI99714.1 - 2.1e-08 34.1 0.0 4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAI99714.1 - 0.0011 19.7 0.0 0.0037 18.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain GBP PF02263.14 OAI99714.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Tcf25 PF04910.9 OAI99716.1 - 6.8e-76 255.5 0.0 9.4e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 XPC-binding PF09280.6 OAI99716.1 - 0.072 12.5 1.4 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 XPC-binding domain YqfQ PF14181.1 OAI99716.1 - 0.47 10.4 6.2 0.079 13.0 0.4 2.4 2 0 0 2 2 2 0 YqfQ-like protein BSP_II PF05432.6 OAI99716.1 - 4.7 6.4 17.5 1.6 7.9 2.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) NDK PF00334.14 OAI99717.1 - 3.2e-29 101.4 0.0 4e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Spt20 PF12090.3 OAI99718.1 - 2.7e-29 101.8 0.0 9.8e-25 86.9 0.0 5.5 4 2 0 4 4 4 2 Spt20 family TIM PF00121.13 OAI99719.1 - 3.5e-92 307.9 0.3 4.1e-92 307.6 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 OAI99719.1 - 0.013 14.7 0.2 0.19 10.9 0.0 2.1 1 1 1 2 2 2 0 CutC family CRAL_TRIO PF00650.15 OAI99720.1 - 7.4e-29 100.2 0.0 1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAI99720.1 - 1.3e-08 34.8 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Citrate_synt PF00285.16 OAI99727.1 - 1.9e-94 316.3 0.0 2.4e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 OAI99727.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone HTH_WhiA PF02650.9 OAI99727.1 - 0.073 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain MutS_V PF00488.16 OAI99728.1 - 4.4e-71 238.9 0.0 1e-70 237.8 0.0 1.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAI99728.1 - 7.3e-37 127.1 2.1 1.2e-36 126.4 1.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAI99728.1 - 2e-23 82.5 0.0 5.8e-23 81.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 OAI99728.1 - 1.5e-10 41.1 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 OAI99728.1 - 1.9e-10 40.9 0.0 5.6e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 MutS domain II UCH PF00443.24 OAI99729.1 - 2.1e-28 99.1 0.0 4.9e-28 97.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAI99729.1 - 4.6e-12 45.8 0.1 8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 OAI99729.1 - 0.0015 18.0 0.0 0.0042 16.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HLH PF00010.21 OAI99731.1 - 6.6e-07 28.9 0.0 2e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 OAI99732.1 - 6.8e-49 163.5 9.3 3e-16 58.9 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CCCH PF00642.19 OAI99733.1 - 0.00022 20.8 1.5 0.0004 19.9 1.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CLPTM1 PF05602.7 OAI99736.1 - 6.1e-92 308.6 0.0 6.6e-79 265.6 0.0 3.0 3 0 0 3 3 3 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 OAI99736.1 - 5.6e-11 41.8 1.0 2e-08 33.6 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat Mito_carr PF00153.22 OAI99737.1 - 1e-70 233.5 3.2 6e-23 80.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Carboxyl_trans PF01039.17 OAI99738.1 - 1e-139 466.0 0.0 1.3e-139 465.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 OAI99738.1 - 0.0022 17.2 0.2 0.23 10.6 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.9 OAI99738.1 - 0.039 13.5 0.1 12 5.4 0.0 2.6 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH PF00378.15 OAI99738.1 - 0.056 12.5 2.0 0.12 11.5 0.1 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase family DUF3477 PF11963.3 OAI99738.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3477) Glutaredoxin PF00462.19 OAI99739.1 - 3.1e-18 65.5 0.0 5.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin PDCD2_C PF04194.8 OAI99741.1 - 1.3e-23 83.4 0.0 3.9e-21 75.3 0.0 4.1 3 1 1 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain Daxx PF03344.10 OAI99741.1 - 0.36 9.2 31.8 0.2 10.1 11.7 2.2 2 0 0 2 2 2 0 Daxx Family NOA36 PF06524.7 OAI99741.1 - 1.5 8.0 26.3 1.1 8.4 6.8 2.5 2 0 0 2 2 2 0 NOA36 protein NAD_binding_8 PF13450.1 OAI99742.1 - 2.7e-07 30.4 0.0 7.1e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAI99742.1 - 0.00029 20.7 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAI99742.1 - 0.046 14.1 0.2 14 6.1 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAI99742.1 - 0.048 13.7 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAI99742.1 - 0.17 10.6 0.5 0.33 9.7 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.17 OAI99743.1 - 3.7e-55 187.2 0.0 4.4e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Met_10 PF02475.11 OAI99744.1 - 3.4e-50 170.4 0.0 6.4e-41 140.1 0.0 2.5 2 1 0 2 2 2 2 Met-10+ like-protein PBD PF00786.23 OAI99745.1 - 0.00015 22.1 0.0 0.00061 20.1 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain adh_short PF00106.20 OAI99753.1 - 1.5e-15 57.5 0.1 2.6e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAI99753.1 - 1.1e-07 31.7 0.1 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAI99753.1 - 2.8e-05 24.0 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAI99753.1 - 0.0059 16.6 0.6 0.017 15.1 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 OAI99753.1 - 0.039 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIB PF00382.14 OAI99753.1 - 0.04 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat 3HCDH_N PF02737.13 OAI99753.1 - 0.09 12.4 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 OAI99753.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cofilin_ADF PF00241.15 OAI99754.1 - 8.2e-12 45.1 0.0 9.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TraX PF05857.6 OAI99754.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 TraX protein zf-CCHC_2 PF13696.1 OAI99756.1 - 0.023 14.1 2.1 0.023 14.1 1.5 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 OAI99756.1 - 0.21 11.5 2.4 0.47 10.4 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 OAI99757.1 - 2.8e-84 281.9 0.0 3.9e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAI99757.1 - 3.5e-21 75.5 0.0 2e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAI99757.1 - 4.7e-07 29.3 0.0 1.5e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 GAG-pre-integrase domain Suppressor_P21 PF11479.3 OAI99759.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 RNA silencing suppressor P21 Abhydrolase_5 PF12695.2 OAI99760.1 - 0.0028 17.4 0.1 0.017 14.9 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAI99760.1 - 0.051 12.4 0.0 0.12 11.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme FAD_binding_3 PF01494.14 OAI99761.1 - 1.9e-09 37.0 0.0 3.8e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 OAI99761.1 - 0.0063 15.3 0.0 0.024 13.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase IBR PF01485.16 OAI99763.1 - 3.9e-20 71.4 49.3 2e-12 46.7 5.1 4.8 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 OAI99763.1 - 0.00011 21.7 6.7 0.00011 21.7 4.7 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAI99763.1 - 0.0004 20.3 5.3 0.0004 20.3 3.7 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99763.1 - 0.00094 18.9 5.8 0.00094 18.9 4.0 3.8 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 OAI99763.1 - 0.0085 15.8 7.2 0.0085 15.8 5.0 4.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_4 PF14570.1 OAI99763.1 - 2 8.0 33.6 0.72 9.4 2.9 4.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 OAI99764.1 - 2.8e-09 36.1 39.6 6.8e-08 31.6 23.3 3.2 1 1 1 2 2 2 1 Major Facilitator Superfamily FixP_N PF14715.1 OAI99764.1 - 0.84 9.0 3.3 4.3 6.8 0.2 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP RabGAP-TBC PF00566.13 OAI99765.1 - 1.5e-16 60.4 0.0 4.7e-06 26.2 0.0 3.8 3 1 0 3 3 3 3 Rab-GTPase-TBC domain QRPTase_C PF01729.14 OAI99770.1 - 4.4e-44 149.9 0.3 6.4e-44 149.4 0.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAI99770.1 - 4.5e-21 74.4 0.0 1.2e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Lung_7-TM_R PF06814.8 OAI99771.1 - 9.6e-53 179.0 17.2 1.5e-52 178.3 11.9 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor YlaC PF10777.4 OAI99771.1 - 0.85 9.1 8.6 7.9 6.0 2.7 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC ASFV_L11L PF05293.6 OAI99771.1 - 5.1 7.2 7.7 1.3 9.1 0.4 2.6 2 0 0 2 2 2 0 African swine fever virus (ASFV) L11L protein MAP65_ASE1 PF03999.7 OAI99772.1 - 0.17 10.4 0.1 0.23 10.0 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4282 PF14110.1 OAI99772.1 - 2.7 8.2 7.3 0.96 9.6 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4282) Methyltransf_11 PF08241.7 OAI99773.1 - 2.2e-18 66.4 0.0 4.8e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAI99773.1 - 2.2e-15 56.5 0.0 3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI99773.1 - 9.3e-12 45.5 0.0 2.2e-11 44.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAI99773.1 - 3e-11 43.5 0.0 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAI99773.1 - 6.4e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAI99773.1 - 1.1e-10 41.8 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAI99773.1 - 3.9e-10 39.7 0.0 4e-08 33.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAI99773.1 - 4.1e-10 39.1 0.0 5.9e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAI99773.1 - 0.00019 20.8 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAI99773.1 - 0.00047 19.2 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 OAI99773.1 - 0.0016 16.8 0.0 0.0021 16.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPMT PF05724.6 OAI99773.1 - 0.0016 17.9 0.0 0.0049 16.3 0.0 1.8 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.15 OAI99773.1 - 0.0068 15.5 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 OAI99773.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 OAI99773.1 - 0.03 12.9 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 OAI99773.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase S1 PF00575.18 OAI99775.1 - 1e-40 137.6 13.5 8.7e-08 32.1 0.2 10.3 11 1 0 11 11 11 7 S1 RNA binding domain TPR_16 PF13432.1 OAI99775.1 - 9.5e-12 45.2 0.0 0.00045 20.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 OAI99775.1 - 8.7e-08 32.2 9.4 8.9e-05 22.3 0.0 3.5 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 OAI99775.1 - 2.1e-07 31.1 0.0 1.2 9.5 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAI99775.1 - 1.9e-05 24.8 1.3 5.3 7.9 0.0 5.9 3 1 3 6 6 6 2 Tetratricopeptide repeat NRDE-2 PF08424.5 OAI99775.1 - 0.00028 19.8 2.6 0.024 13.5 0.5 3.2 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 OAI99775.1 - 0.0023 18.2 0.5 4.4 7.9 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RuvA_N PF01330.16 OAI99775.1 - 0.27 11.0 0.7 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 RuvA N terminal domain EamA PF00892.15 OAI99776.1 - 0.021 14.8 2.1 0.021 14.8 1.5 2.2 2 0 0 2 2 2 0 EamA-like transporter family ThiF PF00899.16 OAI99777.1 - 4.1e-16 59.0 0.0 1.9e-15 56.8 0.0 2.0 3 0 0 3 3 3 1 ThiF family WD40 PF00400.27 OAI99778.1 - 1.7e-21 75.2 12.1 2.1e-07 30.5 0.1 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat KilA-N PF04383.8 OAI99779.1 - 0.00091 18.8 0.0 0.12 12.0 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Es2 PF09751.4 OAI99780.1 - 2.2e-60 205.2 13.4 6.9e-60 203.6 9.3 1.9 1 1 0 1 1 1 1 Nuclear protein Es2 CN_hydrolase PF00795.17 OAI99782.1 - 3.7e-19 68.8 0.0 2.2e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase DUF4098 PF13345.1 OAI99786.1 - 7.2e-10 38.6 3.1 2.5e-06 27.3 0.1 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4098) Velvet PF11754.3 OAI99788.1 - 7.8e-58 195.4 0.0 7.2e-37 126.9 0.0 2.2 2 0 0 2 2 2 2 Velvet factor DUF4098 PF13345.1 OAI99789.1 - 3.3e-08 33.3 13.1 9.4e-06 25.4 4.1 4.0 3 2 0 3 3 3 2 Domain of unknown function (DUF4098) PUA PF01472.15 OAI99789.1 - 0.012 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 PUA domain UAA PF08449.6 OAI99791.1 - 3.9e-13 48.9 20.2 1.8e-07 30.4 1.0 2.0 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 OAI99791.1 - 8.3e-09 35.2 3.9 8.3e-09 35.2 2.7 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAI99791.1 - 0.015 15.3 4.7 0.015 15.3 3.2 2.3 2 0 0 2 2 2 0 EamA-like transporter family Aminotran_5 PF00266.14 OAI99792.1 - 5.1e-29 101.1 0.0 7.5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans PF04082.13 OAI99796.1 - 1.6e-16 59.9 0.0 2.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAI99796.1 - 1.9e-06 27.6 9.7 3.4e-06 26.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GLTP PF08718.6 OAI99800.1 - 3e-44 150.6 0.0 7.1e-44 149.4 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) DWNN PF08783.6 OAI99801.1 - 4.5e-31 106.6 0.0 8.2e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 OAI99801.1 - 2.9e-06 26.6 3.0 7.2e-06 25.3 2.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAI99801.1 - 1.5e-05 24.6 2.0 3.4e-05 23.5 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 OAI99801.1 - 0.00014 21.8 12.2 0.00014 21.8 8.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 OAI99801.1 - 0.0019 17.8 0.2 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_4 PF15227.1 OAI99801.1 - 0.89 9.4 12.7 2 8.3 8.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 OAI99801.1 - 2.3 7.9 13.5 4.1 7.1 9.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99801.1 - 4.1 7.3 18.7 0.062 13.1 8.1 1.6 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 OAI99801.1 - 4.9 6.9 13.8 0.5 10.0 6.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CLTH PF10607.4 OAI99802.1 - 1.7e-29 102.3 0.0 2.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAI99802.1 - 4.6e-11 42.0 0.6 8.6e-11 41.2 0.1 1.8 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.14 OAI99802.1 - 0.00051 20.3 4.7 0.00051 20.3 3.2 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein PTS_2-RNA PF01885.11 OAI99803.1 - 2e-47 160.9 0.0 9.5e-47 158.7 0.0 2.0 2 1 0 2 2 2 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Ribosomal_L24e PF01246.15 OAI99804.1 - 9.5e-32 108.6 0.7 9.5e-32 108.6 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e GlcNAc PF11397.3 OAI99804.1 - 0.024 13.7 3.0 0.031 13.3 2.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) DUF775 PF05603.7 OAI99804.1 - 0.16 11.4 0.9 0.19 11.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PVL_ORF50 PF07768.6 OAI99804.1 - 0.51 10.3 6.6 0.74 9.8 4.6 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family DUF1505 PF07403.6 OAI99805.1 - 0.059 13.3 0.1 0.064 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) Toxin_25 PF08095.6 OAI99805.1 - 0.51 10.1 5.1 0.18 11.5 1.6 1.7 1 1 0 1 1 1 0 Hefutoxin family Trypan_PARP PF05887.6 OAI99806.1 - 0.022 14.5 4.2 0.033 14.0 2.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Macoilin PF09726.4 OAI99806.1 - 2.6 6.2 6.9 2.9 6.0 4.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 OAI99806.1 - 3.2 7.8 11.0 11 6.0 7.6 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pmp3 PF01679.12 OAI99807.1 - 1.5e-15 56.5 5.3 2.2e-15 56.0 3.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ada3 PF10198.4 OAI99808.1 - 2.1e-27 95.4 0.0 9.1e-27 93.3 0.0 2.0 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Histone PF00125.19 OAI99810.1 - 1.4e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAI99810.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAI99811.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAI99811.1 - 4.3e-07 29.8 0.1 8.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAI99811.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 OAI99811.1 - 0.034 14.6 0.3 0.045 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 OAI99811.1 - 0.037 13.5 0.1 0.059 12.8 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain WH1 PF00568.18 OAI99812.1 - 8.3e-14 51.2 0.0 2.6e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 WH1 domain PBD PF00786.23 OAI99812.1 - 2.5e-09 37.3 0.0 5.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 OAI99812.1 - 8.4e-06 25.2 0.3 2e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 WH2 motif Lactamase_B_2 PF12706.2 OAI99813.1 - 9.8e-24 83.9 0.0 4.8e-23 81.7 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 OAI99813.1 - 2.5e-10 39.6 0.0 9e-10 37.8 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 OAI99813.1 - 3.4e-06 26.8 0.0 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily LRR_4 PF12799.2 OAI99817.1 - 2.4e-11 43.0 20.6 3.4e-05 23.3 1.6 5.5 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAI99817.1 - 3e-10 39.6 15.8 5.4e-09 35.6 5.3 4.3 4 3 2 6 6 6 2 Leucine rich repeat EutN_CcmL PF03319.8 OAI99817.1 - 0.024 15.0 0.1 0.068 13.5 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome LRR_9 PF14580.1 OAI99817.1 - 0.025 14.1 0.2 0.25 10.9 0.0 2.5 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.28 OAI99817.1 - 0.16 12.1 21.5 3.4 8.0 0.6 7.8 8 1 1 9 9 9 0 Leucine Rich Repeat LRR_7 PF13504.1 OAI99817.1 - 1.2 9.5 25.8 1.4 9.3 0.6 7.9 10 0 0 10 10 10 0 Leucine rich repeat LRR_6 PF13516.1 OAI99817.1 - 3.3 8.0 19.7 30 5.0 0.3 7.0 8 0 0 8 8 8 0 Leucine Rich repeat RXT2_N PF08595.6 OAI99817.1 - 3.9 7.2 18.4 0.049 13.4 3.9 3.3 2 1 1 3 3 3 0 RXT2-like, N-terminal HMG_box PF00505.14 OAI99818.1 - 4.1e-09 36.5 0.2 6.9e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 6PF2K PF01591.13 OAI99820.1 - 3.3e-63 212.7 0.0 5e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 OAI99820.1 - 2.7e-21 76.2 0.2 9.1e-21 74.5 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 OAI99820.1 - 2.4e-06 27.4 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAI99820.1 - 0.00019 22.2 0.6 0.0085 16.9 0.0 3.0 3 1 1 4 4 4 1 AAA domain KTI12 PF08433.5 OAI99820.1 - 0.00061 19.0 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF2070 PF09843.4 OAI99820.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DDE_1 PF03184.14 OAI99821.1 - 6.8e-35 120.1 0.0 1.2e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAI99821.1 - 2.4e-11 43.2 2.1 3.1e-11 42.9 0.0 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HIT PF01230.18 OAI99822.1 - 7.1e-23 80.9 0.1 1.2e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAI99822.1 - 1.1e-11 45.0 0.1 1.6e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 OAI99822.1 - 4.2e-07 29.6 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF3808 PF10300.4 OAI99823.1 - 1.3e-80 271.2 0.0 3.8e-80 269.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 OAI99823.1 - 7.4e-06 25.3 0.6 0.002 17.7 0.1 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAI99823.1 - 1.6e-05 24.4 0.7 0.046 13.6 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI99823.1 - 9.8e-05 21.9 1.5 0.094 12.3 0.0 3.6 3 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 OAI99823.1 - 0.001 18.9 2.0 2.8 7.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAI99823.1 - 0.013 15.9 0.2 4.4 7.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAI99823.1 - 0.02 14.4 1.2 1.3 8.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAI99823.1 - 0.022 14.5 0.8 3.2 7.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 OAI99824.1 - 3.5e-48 164.0 0.0 3.6e-47 160.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99824.1 - 5.2e-17 61.7 0.0 7.9e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 OAI99824.1 - 1.5e-10 41.0 0.0 3.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 OAI99824.1 - 8.8e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAI99824.1 - 0.0007 18.7 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kv2channel PF03521.9 OAI99824.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel FHA PF00498.21 OAI99825.1 - 2.4e-05 24.3 0.0 6.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain ECH PF00378.15 OAI99827.1 - 9.3e-38 129.7 0.2 5.3e-25 87.9 0.1 2.4 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family GMC_oxred_N PF00732.14 OAI99830.1 - 3.7e-63 213.4 0.0 4.9e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAI99830.1 - 3.4e-29 101.9 0.0 6.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAI99830.1 - 5.3e-08 32.1 0.7 1.6e-05 23.9 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAI99830.1 - 1.4e-05 24.2 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 OAI99830.1 - 1.4e-05 24.1 0.1 1.4e-05 24.1 0.0 2.5 3 0 0 3 3 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAI99830.1 - 3.8e-05 23.6 3.5 4e-05 23.5 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 OAI99830.1 - 0.00016 21.8 3.5 0.0058 16.7 0.0 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAI99830.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAI99830.1 - 0.0083 15.2 2.1 0.009 15.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 OAI99830.1 - 0.041 12.3 0.6 0.17 10.3 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 OAI99830.1 - 0.042 12.4 0.3 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 OAI99830.1 - 0.045 13.5 0.1 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding adh_short PF00106.20 OAI99831.1 - 9.6e-23 80.9 3.0 8e-22 77.9 2.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAI99831.1 - 1.2e-18 67.8 0.3 4.8e-18 65.8 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAI99831.1 - 5.1e-08 32.7 1.1 1.5e-07 31.2 0.7 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 OAI99831.1 - 0.00056 19.4 0.5 0.0023 17.3 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 OAI99831.1 - 0.0061 16.6 0.4 0.023 14.8 0.2 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 OAI99831.1 - 0.036 13.2 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 OAI99831.1 - 0.076 13.0 0.6 0.22 11.5 0.3 1.7 2 0 0 2 2 2 0 NADH(P)-binding zf-CCHC PF00098.18 OAI99832.1 - 1.1e-09 37.7 14.4 5.8e-05 22.8 1.7 2.7 2 0 0 2 2 2 2 Zinc knuckle DUF1897 PF09005.5 OAI99832.1 - 9.8e-09 34.5 19.7 8.5e-05 21.9 1.4 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) zf-CCHC_3 PF13917.1 OAI99832.1 - 9.4e-07 28.4 10.6 0.00017 21.2 2.4 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 OAI99832.1 - 2.9e-06 26.8 0.3 5.4e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAI99832.1 - 0.00032 20.2 0.1 0.00077 19.0 0.1 1.7 1 0 0 1 1 1 1 KH domain zf-C4pol PF14260.1 OAI99832.1 - 0.34 10.9 4.9 24 5.0 0.7 2.3 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC_4 PF14392.1 OAI99832.1 - 0.54 9.9 10.2 2.7 7.7 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Robl_LC7 PF03259.12 OAI99834.1 - 6e-07 28.9 0.0 1.1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Roadblock/LC7 domain Nucleoplasmin PF03066.10 OAI99834.1 - 0.055 12.9 0.2 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 OAI99834.1 - 2.1 8.5 6.5 0.68 10.1 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 OAI99834.1 - 3.4 6.8 4.8 4.7 6.3 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein SKN1 PF03935.10 OAI99835.1 - 7.9e-155 515.8 0.2 1.1e-154 515.3 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF2567 PF10821.3 OAI99835.1 - 0.32 10.4 2.8 16 4.9 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2567) zf-C3HC4_2 PF13923.1 OAI99836.1 - 2.6e-11 43.3 9.6 2.6e-11 43.3 6.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99836.1 - 2.4e-09 36.8 9.3 2.4e-09 36.8 6.4 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAI99836.1 - 7.9e-08 31.8 6.7 7.9e-08 31.8 4.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAI99836.1 - 8.2e-08 31.8 6.3 8.2e-08 31.8 4.4 2.8 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 OAI99836.1 - 8.5e-08 31.7 9.0 8.5e-08 31.7 6.2 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAI99836.1 - 2.9e-05 23.6 5.2 2.9e-05 23.6 3.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAI99836.1 - 3.3e-05 23.5 2.3 3.3e-05 23.5 1.6 2.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAI99836.1 - 0.00052 19.8 9.2 0.00052 19.8 6.3 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAI99836.1 - 0.0029 17.6 4.2 0.0029 17.6 2.9 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 OAI99836.1 - 0.062 12.8 4.0 0.17 11.4 2.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 OAI99836.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain MAD PF05557.8 OAI99837.1 - 1.5e-30 106.0 55.0 2e-27 95.6 12.7 2.9 2 1 0 2 2 2 2 Mitotic checkpoint protein KIAA1430 PF13879.1 OAI99837.1 - 9.6e-05 22.7 1.6 0.00066 20.0 0.0 2.9 2 0 0 2 2 2 1 KIAA1430 homologue VQ PF05678.9 OAI99837.1 - 0.039 13.0 0.4 0.085 11.9 0.3 1.6 1 0 0 1 1 1 0 VQ motif HALZ PF02183.13 OAI99837.1 - 0.97 9.1 24.4 0.61 9.8 0.3 6.0 6 1 0 6 6 6 0 Homeobox associated leucine zipper Coatomer_WDAD PF04053.9 OAI99838.1 - 1.6e-138 462.2 0.0 2.6e-138 461.5 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 OAI99838.1 - 3.2e-80 269.7 0.0 4.8e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 OAI99838.1 - 1.1e-50 167.8 11.1 4.4e-11 42.2 0.0 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat Clathrin PF00637.15 OAI99838.1 - 0.0096 15.5 0.1 0.026 14.1 0.1 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS Nup160 PF11715.3 OAI99838.1 - 0.015 13.4 4.9 0.13 10.3 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.12 OAI99838.1 - 0.1 12.5 0.1 12 6.1 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID-31kDa PF02291.10 OAI99839.1 - 5e-39 133.0 0.0 7.2e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 OAI99839.1 - 0.0029 17.2 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated zf-BED PF02892.10 OAI99843.1 - 0.016 14.9 0.2 0.048 13.4 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger DUF4632 PF15451.1 OAI99843.1 - 0.053 13.4 0.1 0.053 13.4 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4632) zf-BED PF02892.10 OAI99845.1 - 0.041 13.6 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 BED zinc finger DUF605 PF04652.11 OAI99845.1 - 1.5 8.1 19.8 2 7.7 13.7 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 OAI99845.1 - 3.7 5.6 5.3 4.4 5.4 3.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phage_pRha PF09669.5 OAI99846.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) G_glu_transpept PF01019.16 OAI99847.1 - 4.2e-26 91.5 0.0 3.4e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase MSC PF09402.5 OAI99848.1 - 1.6e-22 79.7 0.0 2.3e-11 42.9 0.1 3.2 3 0 0 3 3 3 3 Man1-Src1p-C-terminal domain NGP1NT PF08153.7 OAI99849.1 - 1.5e-41 141.3 0.0 1.5e-41 141.3 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 OAI99849.1 - 1.6e-17 63.5 0.0 1.7e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.16 OAI99849.1 - 0.00032 19.9 0.1 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 OAI99849.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 OAI99849.1 - 0.0024 17.0 0.0 0.0066 15.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF572 PF04502.8 OAI99849.1 - 0.076 12.2 15.4 0.17 11.0 10.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dynamin_N PF00350.18 OAI99849.1 - 0.25 11.1 9.7 0.27 11.0 0.0 4.6 4 1 1 5 5 5 0 Dynamin family DCP1 PF06058.8 OAI99850.1 - 2.6e-15 56.5 0.0 5.3e-08 32.9 0.0 2.8 2 1 0 2 2 2 2 Dcp1-like decapping family DNA_mis_repair PF01119.14 OAI99851.1 - 7.4e-32 109.3 0.0 2.7e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAI99851.1 - 4.2e-12 45.8 0.0 1.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAI99851.1 - 4.6e-11 42.4 0.0 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nucleo_P87 PF07267.6 OAI99851.1 - 0.89 8.1 2.3 1.4 7.5 1.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Linker_histone PF00538.14 OAI99852.1 - 1.4e-16 60.3 0.2 2.5e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family PqqD PF05402.7 OAI99852.1 - 0.042 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CobT PF06213.7 OAI99852.1 - 0.057 12.5 7.2 0.073 12.1 5.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MRI PF15325.1 OAI99852.1 - 0.21 12.5 15.4 0.19 12.7 3.5 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection BTV_NS2 PF04514.7 OAI99852.1 - 0.3 9.9 5.8 0.33 9.7 4.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3446 PF11928.3 OAI99852.1 - 0.78 9.9 17.1 0.76 10.0 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 OAI99852.1 - 1.2 8.5 30.5 0.043 13.2 12.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 OAI99852.1 - 1.8 8.6 21.6 0.045 13.8 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CDC45 PF02724.9 OAI99852.1 - 6.7 4.6 9.8 11 3.9 6.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Bromodomain PF00439.20 OAI99853.1 - 1.4e-25 89.0 0.1 2.9e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 OAI99853.1 - 1.1e-08 35.0 0.3 2.2e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAI99853.1 - 8.2e-08 32.1 0.1 1.8e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Methyltrn_RNA_3 PF02598.12 OAI99854.1 - 9.5e-77 258.1 0.0 1.2e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase Trypan_PARP PF05887.6 OAI99854.1 - 0.00072 19.3 9.4 0.00072 19.3 6.5 1.9 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.1 OAI99854.1 - 0.72 10.1 6.4 1.7 8.9 4.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.13 OAI99855.1 - 1.3e-05 24.9 3.9 4e-05 23.4 2.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 OAI99859.1 - 0.42 8.8 6.7 0.51 8.5 4.7 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1293 PF06950.6 OAI99860.1 - 0.1 12.5 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1293) Reprolysin_5 PF13688.1 OAI99862.1 - 1.1e-44 152.7 5.4 1.1e-44 152.7 3.7 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAI99862.1 - 1e-40 139.4 0.2 2.2e-40 138.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAI99862.1 - 1.3e-37 129.5 2.1 1.3e-37 129.5 1.5 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 OAI99862.1 - 5.9e-18 65.5 0.1 5.9e-18 65.5 0.1 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 OAI99862.1 - 4.8e-14 52.3 22.7 4.8e-14 52.3 15.7 4.3 4 1 1 5 5 5 1 Disintegrin Reprolysin PF01421.14 OAI99862.1 - 1.3e-09 37.9 3.7 1.6e-08 34.3 0.0 3.0 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 OAI99862.1 - 6.3e-08 32.4 0.1 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M66 PF10462.4 OAI99862.1 - 0.086 11.6 0.3 0.14 10.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Mem_trans PF03547.13 OAI99862.1 - 0.14 10.4 0.2 0.35 9.1 0.2 1.6 1 0 0 1 1 1 0 Membrane transport protein Peptidase_M64 PF09471.5 OAI99862.1 - 0.85 9.1 1.7 1.1 8.8 0.2 1.7 2 0 0 2 2 2 0 IgA Peptidase M64 MCR_alpha PF02249.12 OAI99863.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Ran_BP1 PF00638.13 OAI99864.1 - 7.1e-15 55.1 0.6 1.2e-07 31.8 0.0 2.6 3 0 0 3 3 3 2 RanBP1 domain Thiolase_N PF00108.18 OAI99865.1 - 3e-82 275.5 5.9 3e-82 275.5 4.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAI99865.1 - 9.5e-44 147.7 0.7 2.3e-43 146.5 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAI99865.1 - 0.065 12.7 3.6 0.099 12.0 0.1 2.8 3 1 1 4 4 4 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 OAI99865.1 - 0.081 12.9 0.1 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Histone PF00125.19 OAI99866.1 - 8.6e-14 51.4 0.1 1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI99866.1 - 0.00012 22.2 0.0 0.00016 21.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAI99866.1 - 0.00024 20.9 0.1 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAI99866.1 - 0.00077 19.4 0.1 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAI99866.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 OAI99867.1 - 5.5e-29 100.1 1.1 8.4e-29 99.5 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAI99867.1 - 4.7e-05 23.4 0.1 7.2e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAI99867.1 - 0.0019 18.2 0.2 0.0037 17.2 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAI99867.1 - 0.028 14.1 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Prenyltransf PF01255.14 OAI99868.1 - 3.6e-36 124.3 0.0 5.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase XPA_C PF05181.7 OAI99868.1 - 4e-27 93.5 1.2 7.5e-27 92.6 0.8 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Rer1 PF03248.8 OAI99868.1 - 0.047 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Rer1 family ABC_membrane PF00664.18 OAI99871.1 - 3.8e-55 187.2 22.5 1.2e-28 100.3 5.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAI99871.1 - 9.9e-51 171.6 1.8 1.5e-26 93.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.18 OAI99871.1 - 2e-06 27.7 0.6 0.095 12.6 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 OAI99871.1 - 2.8e-06 26.7 0.1 0.063 12.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAI99871.1 - 4.2e-06 26.3 0.5 0.0043 16.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 OAI99871.1 - 4.6e-06 27.1 0.2 0.19 12.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 OAI99871.1 - 5.2e-06 26.6 0.1 0.43 10.4 0.0 4.2 3 1 1 4 4 4 1 AAA domain SMC_N PF02463.14 OAI99871.1 - 7.8e-05 22.0 1.6 1.7 7.8 0.1 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 OAI99871.1 - 0.00022 22.0 0.0 0.31 11.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 OAI99871.1 - 0.00027 20.7 3.4 0.28 11.0 0.0 3.5 3 0 0 3 3 3 2 Dynamin family AAA_23 PF13476.1 OAI99871.1 - 0.00068 20.0 9.8 0.41 10.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 OAI99871.1 - 0.0017 17.5 1.9 0.35 10.0 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAI99871.1 - 0.0044 17.0 4.5 0.17 11.8 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 OAI99871.1 - 0.0098 16.2 4.9 0.65 10.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 OAI99871.1 - 0.016 14.8 0.3 8.3 6.1 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAI99871.1 - 0.057 12.8 0.3 9 5.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ycf1 PF05758.7 OAI99871.1 - 0.086 10.5 0.0 0.14 9.8 0.0 1.3 1 0 0 1 1 1 0 Ycf1 AAA_15 PF13175.1 OAI99871.1 - 0.24 10.3 0.0 0.24 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain RNase_H2-Ydr279 PF09468.5 OAI99871.1 - 5.7 6.0 12.4 1.1 8.4 3.7 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) NCA2 PF08637.5 OAI99872.1 - 1.7e-75 253.6 0.0 4e-75 252.3 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Transposase_21 PF02992.9 OAI99873.1 - 8.5e-25 87.1 0.0 1.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAI99873.1 - 0.0011 18.4 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Nrap PF03813.9 OAI99875.1 - 6.8e-236 785.2 0.0 8e-236 784.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Nop14 PF04147.7 OAI99875.1 - 0.0024 15.9 15.2 0.0034 15.4 10.5 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 OAI99875.1 - 1 8.6 22.2 1.7 7.8 15.4 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAI99875.1 - 2.1 6.7 17.8 3.2 6.1 12.4 1.1 1 0 0 1 1 1 0 Daxx Family Cnd2 PF05786.9 OAI99875.1 - 2.4 6.5 11.6 3.6 5.9 8.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 BUD22 PF09073.5 OAI99875.1 - 8 5.4 21.8 12 4.8 15.1 1.2 1 0 0 1 1 1 0 BUD22 Tropomyosin_1 PF12718.2 OAI99876.1 - 0.012 15.4 8.9 0.021 14.6 1.8 3.3 1 1 2 3 3 3 0 Tropomyosin like GerPC PF10737.4 OAI99876.1 - 0.016 14.9 1.8 0.016 14.9 1.3 1.6 2 0 0 2 2 2 0 Spore germination protein GerPC Fib_alpha PF08702.5 OAI99876.1 - 0.093 12.8 11.3 0.034 14.2 2.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIVA PF05103.8 OAI99876.1 - 1 9.4 9.0 5.5 7.0 0.4 3.4 2 2 1 3 3 3 0 DivIVA protein Med9 PF07544.8 OAI99876.1 - 1.1 9.0 7.3 1.8 8.3 0.4 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 OAI99876.1 - 2.7 8.4 17.4 0.58 10.5 0.8 5.3 4 2 1 5 5 5 0 SlyX DivIC PF04977.10 OAI99876.1 - 3.4 7.2 14.3 1.1 8.7 0.2 4.3 2 2 3 5 5 5 0 Septum formation initiator Tropomyosin PF00261.15 OAI99876.1 - 4.1 6.4 16.0 0.077 12.0 1.2 2.7 1 1 1 2 2 2 0 Tropomyosin Dicty_REP PF05086.7 OAI99877.1 - 8.3 4.0 7.4 12 3.4 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1749 PF08538.5 OAI99878.1 - 7.2e-49 166.3 0.0 1.5e-46 158.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 OAI99878.1 - 1e-08 35.3 4.1 2e-08 34.4 2.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99878.1 - 1.3e-06 28.2 0.0 3.8e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 OAI99878.1 - 0.098 12.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) DUF3139 PF11337.3 OAI99879.1 - 0.13 12.5 2.7 0.73 10.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Sigma_reg_N PF13800.1 OAI99879.1 - 1 9.4 3.3 4.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF2678 PF10856.3 OAI99879.1 - 1.2 8.9 4.5 0.47 10.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Cytochrom_B_N PF00033.14 OAI99879.1 - 4.5 6.5 10.6 3.1 7.0 3.4 2.7 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB DEAD PF00270.24 OAI99880.1 - 2e-20 72.9 0.0 2.8e-16 59.4 0.0 3.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI99880.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAI99880.1 - 0.00036 20.4 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 OAI99881.1 - 1.3e-37 129.3 22.3 1.6e-36 125.7 16.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Tmemb_55A PF09788.4 OAI99882.1 - 0.073 12.1 2.4 0.15 11.1 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein 55A Lysis_col PF02402.11 OAI99882.1 - 1.3 8.6 5.5 1 9.0 0.1 2.6 2 0 0 2 2 2 0 Lysis protein SUR7 PF06687.7 OAI99882.1 - 5.1 6.5 13.4 1.5 8.3 4.5 2.3 2 1 0 2 2 2 0 SUR7/PalI family DEAD PF00270.24 OAI99887.1 - 8.4e-12 44.8 0.1 2.6e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAI99887.1 - 7e-10 38.6 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 OAI99888.1 - 8.3e-09 35.6 1.3 1.2e-08 35.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Sgf11 PF08209.6 OAI99888.1 - 1.3 8.4 6.6 1.9 7.8 1.7 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-CCHC PF00098.18 OAI99889.1 - 0.0013 18.5 3.9 0.0023 17.7 2.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAI99889.1 - 0.0085 15.5 0.9 0.017 14.5 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Seryl_tRNA_N PF02403.17 OAI99889.1 - 0.045 13.7 9.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 OAI99889.1 - 0.16 11.8 0.2 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PIF1 PF05970.9 OAI99890.1 - 1.4e-22 80.1 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAI99890.1 - 1.3e-11 44.4 0.0 5.4e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAI99890.1 - 7.2e-08 32.0 1.3 1.5e-07 31.0 0.3 2.0 2 0 0 2 2 2 1 Part of AAA domain Helitron_like_N PF14214.1 OAI99890.1 - 3e-06 27.0 0.0 7.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAI99890.1 - 0.0001 22.3 0.0 0.00038 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAI99890.1 - 0.035 14.2 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sigma54_activat PF00158.21 OAI99890.1 - 0.041 13.3 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 OAI99890.1 - 0.15 11.9 0.1 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Torsin COG5 PF10392.4 OAI99891.1 - 0.00037 20.4 4.5 0.00056 19.8 3.1 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 GrpE PF01025.14 OAI99891.1 - 0.00093 18.7 1.0 0.0013 18.3 0.7 1.2 1 0 0 1 1 1 1 GrpE APG17 PF04108.7 OAI99891.1 - 0.0014 17.5 0.6 0.0018 17.1 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF842 PF05811.8 OAI99891.1 - 0.0033 16.8 1.7 0.0046 16.4 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Mod_r PF07200.8 OAI99891.1 - 0.012 15.5 0.7 0.018 14.9 0.5 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Tht1 PF04163.7 OAI99891.1 - 0.021 13.2 0.6 0.024 13.0 0.4 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Tmemb_cc2 PF10267.4 OAI99891.1 - 0.022 13.3 2.3 0.027 13.0 1.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1664 PF07889.7 OAI99891.1 - 0.024 14.4 3.5 0.034 13.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4472 PF14739.1 OAI99891.1 - 0.051 14.0 2.7 1.2 9.5 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Streptin-Immun PF11083.3 OAI99891.1 - 0.09 12.7 0.3 0.17 11.9 0.2 1.5 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein Baculo_PEP_C PF04513.7 OAI99891.1 - 0.1 12.4 5.5 0.32 10.8 2.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 OAI99891.1 - 0.16 11.0 1.7 0.19 10.7 1.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.6 OAI99891.1 - 0.18 11.1 2.1 0.4 10.0 1.5 1.7 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 OAI99891.1 - 0.19 11.8 1.9 0.28 11.2 1.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PEP-utilisers_N PF05524.8 OAI99891.1 - 0.22 11.3 1.4 0.48 10.2 1.0 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal CALCOCO1 PF07888.6 OAI99905.1 - 0.0054 15.0 2.9 0.007 14.7 2.0 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.17 OAI99905.1 - 0.0099 15.8 4.0 0.02 14.9 2.7 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.1 OAI99905.1 - 0.059 13.5 2.1 0.088 13.0 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) FemAB PF02388.11 OAI99905.1 - 0.48 9.0 2.6 0.69 8.5 1.8 1.1 1 0 0 1 1 1 0 FemAB family DivIC PF04977.10 OAI99905.1 - 2.9 7.4 8.7 4.4 6.8 1.4 2.4 1 1 0 2 2 2 0 Septum formation initiator Cyclin_N PF00134.18 OAI99906.1 - 0.027 14.0 0.0 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain Cyclin_N PF00134.18 OAI99907.1 - 0.003 17.1 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain JmjC PF02373.17 OAI99908.1 - 8.5e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAI99908.1 - 0.0092 15.4 0.0 0.033 13.6 0.0 1.9 2 0 0 2 2 2 1 Cupin domain C1_1 PF00130.17 OAI99908.1 - 0.51 10.0 11.3 0.21 11.3 4.6 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_C48 PF02902.14 OAI99909.1 - 1.4e-12 47.7 0.0 4.4e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain JmjC PF02373.17 OAI99911.1 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 OAI99911.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Seryl_tRNA_N PF02403.17 OAI99912.1 - 0.0048 16.8 4.8 0.0071 16.3 3.3 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.4 OAI99912.1 - 0.049 13.6 0.2 0.049 13.6 0.1 1.5 2 0 0 2 2 2 0 Zinc finger-containing protein DUF4600 PF15372.1 OAI99912.1 - 0.072 13.3 2.4 0.1 12.7 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) GreA_GreB_N PF03449.10 OAI99912.1 - 0.2 11.7 3.2 0.39 10.8 2.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal FemAB PF02388.11 OAI99912.1 - 0.26 9.9 3.6 0.33 9.5 2.5 1.1 1 0 0 1 1 1 0 FemAB family Viral_P18 PF04521.8 OAI99912.1 - 0.66 9.4 2.7 0.9 8.9 1.3 1.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DivIC PF04977.10 OAI99912.1 - 1.1 8.8 8.6 3.6 7.1 1.1 2.3 1 1 1 2 2 2 0 Septum formation initiator MMgT PF10270.4 OAI99916.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Membrane magnesium transporter Scramblase PF03803.10 OAI99916.1 - 0.13 11.3 0.0 9.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Scramblase Cyclin_N PF00134.18 OAI99917.1 - 5.4e-12 45.3 0.0 9.8e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAI99917.1 - 2e-11 44.5 0.0 3.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF3546 PF12066.3 OAI99918.1 - 1.2e-14 54.1 0.8 1.2e-14 54.1 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 OAI99918.1 - 0.00021 21.5 0.0 0.00072 19.7 0.0 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Isochorismatase PF00857.15 OAI99919.1 - 1.4e-33 116.2 0.1 1.8e-33 115.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Glyco_transf_4 PF13439.1 OAI99919.1 - 0.13 11.9 0.1 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 MS_channel PF00924.13 OAI99920.1 - 2e-22 79.5 1.3 3.6e-22 78.7 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAI99920.1 - 0.02 14.1 0.0 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 OAI99920.1 - 0.052 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair ADH_N PF08240.7 OAI99921.1 - 7.4e-27 93.2 4.1 1.3e-26 92.4 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAI99921.1 - 3.3e-18 65.4 0.1 5.3e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAI99921.1 - 0.002 18.9 0.0 0.0034 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAI99921.1 - 0.022 13.8 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA PF00004.24 OAI99922.1 - 7.7e-29 100.5 0.0 1.6e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAI99922.1 - 0.00028 20.9 0.1 0.019 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAI99922.1 - 0.0028 17.8 0.0 0.015 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAI99922.1 - 0.0035 17.0 0.2 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAI99922.1 - 0.011 15.4 0.4 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 OAI99922.1 - 0.021 14.2 0.7 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 OAI99922.1 - 0.041 13.7 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAI99922.1 - 0.093 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Avl9 PF09794.4 OAI99922.1 - 0.18 10.2 0.0 6 5.2 0.0 2.1 2 0 0 2 2 2 0 Transport protein Avl9 AAA_24 PF13479.1 OAI99922.1 - 0.19 11.2 0.3 0.54 9.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain HsbA PF12296.3 OAI99923.1 - 2.7e-13 49.8 5.5 4.3e-13 49.1 3.8 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CAP160 PF07918.6 OAI99923.1 - 0.14 11.7 0.7 0.14 11.7 0.5 2.9 3 0 0 3 3 3 0 CAP160 repeat APG6 PF04111.7 OAI99924.1 - 0.1 11.6 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3336 PF11815.3 OAI99925.1 - 1.9e-43 147.4 1.9 3.3e-43 146.6 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 OAI99925.1 - 1.1e-19 71.1 2.9 1.2e-19 71.0 0.1 2.6 2 2 0 2 2 2 1 Patatin-like phospholipase Nop PF01798.13 OAI99926.1 - 7e-58 194.1 0.1 1.4e-57 193.1 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAI99926.1 - 5.7e-25 86.8 0.9 8.6e-25 86.3 0.1 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAI99926.1 - 2.4e-19 69.2 0.0 2.4e-19 69.2 0.0 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain BCDHK_Adom3 PF10436.4 OAI99926.1 - 0.013 15.0 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Nop53 PF07767.6 OAI99926.1 - 0.097 11.6 35.7 0.14 11.1 24.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.3 OAI99926.1 - 0.29 11.7 30.5 0.67 10.6 21.1 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 OAI99926.1 - 0.71 7.8 30.5 1.1 7.2 21.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 OAI99926.1 - 9.1 6.2 23.1 15 5.6 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) BRE1 PF08647.6 OAI99931.1 - 4.1e-16 58.7 11.5 4.1e-16 58.7 7.9 6.6 5 3 3 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 OAI99931.1 - 8.8e-08 32.0 12.1 1.5e-07 31.2 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAI99931.1 - 3e-06 26.7 13.6 5.4e-06 25.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 OAI99931.1 - 1.2e-05 24.9 2.5 2.3e-05 24.0 1.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 OAI99931.1 - 1.6e-05 24.5 11.9 3.9e-05 23.2 8.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAI99931.1 - 1.7e-05 24.3 9.4 3.5e-05 23.3 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAI99931.1 - 0.00018 21.2 9.6 0.00033 20.4 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain Fez1 PF06818.10 OAI99931.1 - 0.00092 19.2 18.0 0.00092 19.2 12.4 5.8 4 1 1 5 5 3 1 Fez1 zf-C3HC4_4 PF15227.1 OAI99931.1 - 0.013 15.4 8.5 0.022 14.6 5.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 OAI99931.1 - 0.041 14.0 5.5 0.087 12.9 3.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1272 PF06906.6 OAI99931.1 - 0.087 12.6 5.2 0.22 11.3 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.1 OAI99931.1 - 0.2 10.9 2.1 0.24 10.6 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.4 OAI99931.1 - 0.27 10.9 1.9 0.63 9.7 1.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-RING_UBOX PF13445.1 OAI99931.1 - 0.37 10.5 5.6 1 9.1 3.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 OAI99931.1 - 0.74 9.3 4.8 2.2 7.8 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.2 OAI99931.1 - 1.3 8.9 8.3 1.5 8.6 4.2 2.2 2 0 0 2 2 2 0 Double zinc ribbon Nsp1_C PF05064.8 OAI99931.1 - 6.1 6.5 17.3 4.5 6.9 2.2 4.7 2 2 1 4 4 4 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 OAI99931.1 - 6.7 6.6 21.4 12 5.8 0.2 6.5 7 1 0 7 7 7 0 Flagella accessory protein C (FlaC) zf-RING_4 PF14570.1 OAI99931.1 - 7.8 6.1 10.2 24 4.5 7.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1690 PF07956.6 OAI99933.1 - 5e-14 52.4 8.3 5e-14 52.4 5.8 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) Apolipoprotein PF01442.13 OAI99933.1 - 0.081 12.4 15.0 0.77 9.2 6.9 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain CDC27 PF09507.5 OAI99933.1 - 0.34 10.0 27.7 0.4 9.8 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sas10_Utp3 PF04000.10 OAI99933.1 - 0.37 11.0 4.0 10 6.4 0.5 2.7 2 1 1 3 3 3 0 Sas10/Utp3/C1D family DUF972 PF06156.8 OAI99933.1 - 0.75 10.1 9.9 0.63 10.4 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Rootletin PF15035.1 OAI99933.1 - 0.84 9.5 15.6 0.92 9.4 6.7 2.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF883 PF05957.8 OAI99933.1 - 0.85 10.0 20.4 0.88 10.0 1.3 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.6 OAI99933.1 - 1.2 9.1 6.0 5.2 7.0 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 OAI99933.1 - 2.6 7.6 13.9 0.92 9.0 7.4 1.8 1 1 1 2 2 2 0 IncA protein Allexi_40kDa PF05549.6 OAI99933.1 - 4.7 6.4 7.8 13 4.9 0.4 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Erp_C PF06780.6 OAI99933.1 - 7.6 6.3 13.3 1.2 8.9 4.3 2.1 2 0 0 2 2 2 0 Erp protein C-terminus COG2 PF06148.6 OAI99933.1 - 7.7 6.3 13.7 19 5.1 0.9 3.2 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TP_methylase PF00590.15 OAI99934.1 - 7.5e-14 51.9 0.9 1.9e-13 50.6 0.1 2.0 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L28 PF00830.14 OAI99935.1 - 4.6e-22 77.6 0.4 7.3e-22 76.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family CsgG PF03783.9 OAI99935.1 - 0.0027 16.8 0.1 0.0061 15.6 0.1 1.5 2 0 0 2 2 2 1 Curli production assembly/transport component CsgG COQ7 PF03232.8 OAI99935.1 - 0.13 11.7 0.1 4.4 6.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Brix PF04427.13 OAI99936.1 - 8.5e-49 165.8 0.1 1.1e-48 165.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 OAI99936.1 - 0.0069 16.0 0.1 0.12 12.0 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2517) Per1 PF04080.8 OAI99937.1 - 2.1e-91 306.0 0.0 3.5e-91 305.3 0.0 1.3 1 0 0 1 1 1 1 Per1-like Arf PF00025.16 OAI99938.1 - 3e-68 228.4 0.0 3.5e-68 228.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAI99938.1 - 7.3e-12 44.6 2.5 1.8e-06 26.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 OAI99938.1 - 8.1e-10 38.2 0.0 1.1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAI99938.1 - 5.5e-08 32.2 0.0 6.6e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAI99938.1 - 1.4e-07 31.4 0.0 3.4e-07 30.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 OAI99938.1 - 6.8e-07 28.8 0.0 8.1e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAI99938.1 - 7.6e-07 29.6 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 OAI99938.1 - 6.7e-05 22.3 0.0 0.0046 16.4 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 OAI99938.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 OAI99938.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 OAI99938.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 OAI99938.1 - 0.05 14.4 0.3 0.25 12.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 OAI99938.1 - 0.07 12.4 0.0 0.24 10.6 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B FTR1 PF03239.9 OAI99939.1 - 7.4e-55 186.0 8.0 1.7e-35 122.4 2.9 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.11 OAI99939.1 - 0.024 13.3 0.1 0.09 11.4 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus glycoprotein M DUF2142 PF09913.4 OAI99939.1 - 0.15 10.7 5.6 0.014 14.0 0.4 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2142) Cu-oxidase PF00394.17 OAI99940.1 - 2.7e-35 121.6 0.4 8.1e-32 110.3 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAI99940.1 - 3e-35 120.7 4.6 3e-35 120.7 3.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAI99940.1 - 8e-27 93.3 10.1 3.4e-26 91.3 1.6 4.0 3 1 0 4 4 4 1 Multicopper oxidase Ribosomal_L6 PF00347.18 OAI99941.1 - 2.2e-19 69.6 0.0 3.9e-12 46.4 0.0 3.6 4 0 0 4 4 4 3 Ribosomal protein L6 Ribosomal_60s PF00428.14 OAI99941.1 - 0.35 11.2 4.2 0.84 10.0 2.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_C50 PF03568.12 OAI99942.1 - 2.3e-81 273.4 0.0 3.3e-81 272.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_8 PF13181.1 OAI99942.1 - 7.4e-05 22.2 0.1 0.31 10.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAI99942.1 - 0.00011 21.7 6.5 0.042 13.4 0.1 4.8 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 OAI99942.1 - 0.00083 19.0 2.1 8.2 6.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAI99942.1 - 0.0011 18.9 12.6 1.4 8.9 0.1 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAI99942.1 - 0.005 16.3 0.1 5.8 6.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAI99942.1 - 0.011 15.4 0.1 15 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIA PF03153.8 OAI99942.1 - 3.3 7.5 10.8 6 6.6 7.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Afi1 PF07792.7 OAI99943.1 - 4.1e-43 146.8 0.0 6.3e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 OAI99943.1 - 1.4e-34 118.1 0.0 3.6e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.4 OAI99943.1 - 2e-10 39.7 0.0 1.2e-05 24.0 0.0 3.2 2 1 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.4 OAI99943.1 - 0.0027 17.0 0.0 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) FXR1P_C PF12235.3 OAI99944.1 - 0.57 10.2 15.9 1.5 8.9 7.2 2.3 1 1 1 2 2 2 0 Fragile X-related 1 protein C terminal E1-E2_ATPase PF00122.15 OAI99945.1 - 1.4e-49 168.2 0.6 2.5e-49 167.4 0.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 OAI99945.1 - 3.3e-39 135.5 0.2 1.5e-32 113.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 OAI99945.1 - 3.8e-18 65.3 0.0 2e-11 43.8 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 OAI99945.1 - 1.1e-11 45.2 0.2 9.4e-11 42.2 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAI99945.1 - 0.0024 17.4 1.3 0.058 12.9 1.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4006 PF13179.1 OAI99945.1 - 1.5 8.4 3.3 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Abhydrolase_6 PF12697.2 OAI99950.1 - 2.2e-15 57.1 0.4 4.1e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAI99950.1 - 3.8e-07 29.9 0.0 9.4e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAI99950.1 - 0.00016 21.2 0.0 0.00067 19.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAI99950.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Spore_coat_CotO PF14153.1 OAI99951.1 - 0.035 13.5 17.8 0.24 10.8 0.8 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF3807 PF12720.2 OAI99951.1 - 0.64 10.1 39.4 0.69 10.0 8.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SAPS PF04499.10 OAI99951.1 - 3.3 6.2 14.2 1.2 7.7 1.8 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 OAI99951.1 - 7.3 6.3 20.8 0.092 12.6 3.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.8 OAI99951.1 - 8.3 5.7 38.2 0.048 13.0 7.4 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal zf-DHHC PF01529.15 OAI99952.1 - 1.7e-40 138.2 2.1 1.7e-40 138.2 1.5 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pox_A14 PF05767.7 OAI99952.1 - 0.13 12.1 0.2 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 CK_II_beta PF01214.13 OAI99953.1 - 1.9e-79 265.4 0.2 4.9e-79 264.1 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit PGA2 PF07543.7 OAI99953.1 - 2 8.2 13.7 5.2 6.8 9.5 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC27 PF09507.5 OAI99953.1 - 3.5 6.7 14.4 8 5.5 10.0 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COX17 PF05051.8 OAI99954.1 - 1.1e-17 63.7 4.3 1.8e-17 63.0 3.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CENP-Q PF13094.1 OAI99955.1 - 0.00029 20.9 1.1 0.00046 20.2 0.7 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit FlgN PF05130.7 OAI99955.1 - 0.075 13.2 1.3 0.16 12.1 0.9 1.5 1 0 0 1 1 1 0 FlgN protein TMF_TATA_bd PF12325.3 OAI99955.1 - 0.12 12.1 5.0 0.049 13.3 1.9 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF342 PF03961.8 OAI99955.1 - 0.12 10.7 0.9 0.17 10.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 OAI99955.1 - 0.55 10.5 4.9 1.1 9.6 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pkinase PF00069.20 OAI99956.1 - 5.2e-32 111.0 0.0 2.1e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAI99956.1 - 2e-09 36.8 0.0 1.7e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_S10 PF00450.17 OAI99957.1 - 7.9e-100 334.9 0.0 1e-99 334.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAI99957.1 - 0.015 15.2 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family CBFB_NFYA PF02045.10 OAI99958.1 - 1.1e-20 73.8 16.6 6.2e-12 45.8 1.4 2.9 3 0 0 3 3 3 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B AAA_21 PF13304.1 OAI99959.1 - 3.2e-11 43.7 3.5 2.2e-05 24.5 0.2 3.2 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 OAI99959.1 - 3.2e-10 39.7 0.0 1.4e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 OAI99959.1 - 1.5e-07 30.8 0.1 1.5e-07 30.8 0.1 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAI99959.1 - 1.8e-06 28.4 58.0 1.8e-06 28.4 40.2 8.4 1 1 3 4 4 4 1 AAA domain AAA_15 PF13175.1 OAI99959.1 - 4.4e-06 26.0 37.2 4.4e-05 22.7 5.6 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_13 PF13166.1 OAI99959.1 - 0.00054 18.5 1.1 0.017 13.6 0.1 7.9 2 1 3 7 7 7 4 AAA domain DUF1829 PF08862.5 OAI99959.1 - 0.00096 19.3 0.9 0.065 13.5 0.1 3.5 2 0 0 2 2 2 1 Domain of unknown function DUF1829 Flavi_capsid PF01003.14 OAI99959.1 - 0.022 14.3 0.1 0.086 12.3 0.1 2.0 1 0 0 1 1 1 0 Flavivirus capsid protein C AAA_29 PF13555.1 OAI99959.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MIF4G PF02854.14 OAI99963.1 - 4.3e-55 186.3 1.6 1.2e-54 184.8 1.1 1.8 1 1 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 OAI99963.1 - 1.9e-12 46.8 0.0 7.5e-12 44.9 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 OAI99963.1 - 0.00076 19.1 0.3 0.005 16.5 0.0 2.4 3 0 0 3 3 3 1 MA3 domain Y_phosphatase2 PF03162.8 OAI99964.1 - 9.4e-51 171.4 0.0 1e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAI99964.1 - 4.6e-05 23.7 0.0 0.0011 19.2 0.0 2.0 1 1 1 2 2 2 2 Tyrosine phosphatase family Adaptin_N PF01602.15 OAI99965.1 - 5.9e-100 335.0 0.0 1.7e-99 333.5 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 OAI99965.1 - 0.00037 20.7 18.1 0.021 15.1 0.6 5.9 4 2 1 5 5 5 2 HEAT repeats Arm PF00514.18 OAI99965.1 - 0.00046 19.8 0.6 6.4 6.7 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 OAI99965.1 - 0.0028 17.5 1.3 0.59 9.9 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CortBP2 PF09727.4 OAI99965.1 - 0.023 14.2 0.5 0.051 13.0 0.3 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 HEAT PF02985.17 OAI99965.1 - 0.033 14.2 2.5 29 5.1 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat Ipi1_N PF12333.3 OAI99965.1 - 0.071 13.0 1.2 0.37 10.7 0.2 2.7 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation PseudoU_synth_2 PF00849.17 OAI99966.1 - 6.6e-27 94.3 0.1 1.1e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cpn60_TCP1 PF00118.19 OAI99967.1 - 5.7e-133 444.0 1.0 6.4e-133 443.8 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.6 OAI99967.1 - 0.043 13.2 0.3 0.33 10.3 0.1 2.5 3 0 0 3 3 3 0 Propionate catabolism activator DUF1408 PF07193.6 OAI99968.1 - 0.91 9.0 5.5 0.65 9.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) LRR_9 PF14580.1 OAI99969.1 - 1.5e-58 197.2 0.1 2.1e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 OAI99969.1 - 6.6e-14 51.4 12.4 1.9e-07 30.6 0.7 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 OAI99969.1 - 4.7e-13 48.4 2.0 3e-06 26.6 0.1 3.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 OAI99969.1 - 0.012 15.6 3.4 2.3 8.5 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 OAI99969.1 - 0.021 14.7 1.9 25 5.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 OAI99969.1 - 0.34 11.2 3.4 31 5.3 0.1 4.3 4 0 0 4 4 4 0 Leucine rich repeat Med3 PF11593.3 OAI99969.1 - 1.1 8.4 11.4 2.2 7.4 7.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Metallophos PF00149.23 OAI99970.1 - 1.3e-39 135.6 0.5 1.7e-39 135.3 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAI99970.1 - 0.0038 17.0 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2268 PF10026.4 OAI99970.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Aldedh PF00171.17 OAI99971.1 - 1e-124 416.3 0.0 1.4e-124 415.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAI99971.1 - 0.014 14.1 0.0 0.027 13.1 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) HSP70 PF00012.15 OAI99972.1 - 2.4e-238 791.9 7.4 2.9e-238 791.6 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAI99972.1 - 1.9e-19 69.4 0.7 1.3e-18 66.6 0.5 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAI99972.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 OAI99972.1 - 0.0014 17.5 0.9 0.0096 14.7 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain StbA PF06406.6 OAI99972.1 - 0.025 13.5 0.0 0.051 12.5 0.0 1.5 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.13 OAI99972.1 - 0.077 12.0 2.9 0.12 11.4 0.1 2.5 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase QRPTase_N PF02749.11 OAI99972.1 - 0.089 12.6 0.1 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Ribosomal_S2 PF00318.15 OAI99973.1 - 7.6e-42 142.9 0.0 1.1e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 Ribosomal_L27 PF01016.14 OAI99974.1 - 4.2e-35 119.3 0.5 7.9e-35 118.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Abhydrolase_3 PF07859.8 OAI99975.1 - 4.4e-30 104.8 0.0 5.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 OAI99975.1 - 0.0016 17.7 0.0 0.6 9.3 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAI99975.1 - 0.0031 17.2 0.0 0.0048 16.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 OAI99976.1 - 1e-05 25.1 0.2 0.074 12.9 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 OAI99977.1 - 4.1e-73 238.8 29.0 1.6e-08 34.0 0.2 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 OAI99977.1 - 2.5e-29 101.7 0.0 1.8e-18 66.5 0.0 2.4 2 0 0 2 2 2 2 Utp13 specific WD40 associated domain Nup160 PF11715.3 OAI99977.1 - 1.3e-06 26.8 14.9 0.52 8.3 0.4 6.4 3 2 3 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAI99977.1 - 3e-05 22.9 0.4 0.095 11.4 0.0 4.1 4 1 1 5 5 5 2 Nup133 N terminal like SNARE_assoc PF09335.6 OAI99980.1 - 9.3e-17 61.3 6.7 9.3e-17 61.3 4.7 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein adh_short PF00106.20 OAI99981.1 - 2.2e-15 56.9 0.2 1e-11 45.0 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 OAI99981.1 - 2.4e-08 34.0 0.3 1.2e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAI99981.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 KR domain ubiquitin PF00240.18 OAI99981.1 - 0.046 13.1 0.1 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family SAC3_GANP PF03399.11 OAI99983.1 - 1.4e-45 155.3 0.0 2.5e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PTCB-BRCT PF12738.2 OAI99984.1 - 6.9e-23 80.2 2.3 2e-08 33.9 0.0 4.5 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 OAI99984.1 - 2.5e-22 78.8 0.0 1.2e-07 31.7 0.0 4.7 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Methyltransf_16 PF10294.4 OAI99985.1 - 2.3e-15 56.4 0.0 4.4e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 OAI99985.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SET PF00856.23 OAI99986.1 - 4.7e-05 23.7 0.0 0.00017 21.9 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 OAI99986.1 - 0.0049 16.7 0.9 0.069 13.0 0.6 2.2 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding F-box PF00646.28 OAI99987.1 - 5.1e-07 29.1 3.3 5.7e-07 29.0 0.4 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 OAI99987.1 - 3.2e-05 23.5 2.4 3.2e-05 23.5 1.6 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 OAI99987.1 - 0.0033 16.9 4.2 1.3 8.7 0.0 4.2 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) Cellulase PF00150.13 OAI99988.1 - 1e-16 60.9 0.8 7.3e-16 58.2 0.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_2 PF00152.15 OAI99989.1 - 1.7e-100 336.0 0.0 3.9e-51 173.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAI99989.1 - 5.5e-08 32.5 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 OAI99989.1 - 0.008 15.7 0.4 1.1 8.8 0.2 2.9 2 1 1 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) UBX PF00789.15 OAI99990.1 - 4e-05 23.5 0.0 9.7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 UBX domain CAF-1_p150 PF11600.3 OAI99990.1 - 0.0015 17.9 10.0 0.0031 16.9 6.9 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Thioredoxin_7 PF13899.1 OAI99990.1 - 0.0044 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like U79_P34 PF03064.11 OAI99990.1 - 0.18 11.2 4.5 0.42 10.0 3.2 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GBP_C PF02841.9 OAI99990.1 - 0.76 8.9 6.1 1.2 8.2 4.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MFS_1 PF07690.11 OAI99991.1 - 4.3e-36 124.3 34.3 4.3e-36 124.3 23.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAI99991.1 - 5.2e-13 48.3 9.3 5.2e-13 48.3 6.4 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter PBP1_TM PF14812.1 OAI99991.1 - 0.0091 16.2 0.1 1.3 9.4 0.4 2.6 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal ESSS PF10183.4 OAI99991.1 - 0.24 11.8 4.0 1.5 9.2 0.3 3.1 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CDC45 PF02724.9 OAI99991.1 - 0.63 8.0 2.9 1 7.3 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein OATP PF03137.15 OAI99991.1 - 1.4 6.9 14.0 1.1 7.1 4.8 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SIS PF01380.17 OAI99992.1 - 2.2e-13 49.9 0.0 8e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 OAI99992.1 - 7.6e-05 22.4 0.0 0.0039 16.9 0.0 2.3 1 1 1 2 2 2 2 SIS domain Glyco_hydro_38 PF01074.17 OAI99993.1 - 5.3e-77 258.7 1.8 8.8e-77 258.0 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 OAI99993.1 - 3.8e-56 190.8 0.0 5.6e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 OAI99993.1 - 1.5e-25 89.1 0.0 3.6e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 OAI99993.1 - 0.0035 16.3 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DKCLD PF08068.7 OAI99996.1 - 6.1e-30 102.9 0.1 2e-29 101.3 0.1 1.8 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 OAI99996.1 - 1.8e-24 86.6 0.2 2.4e-21 76.4 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 OAI99996.1 - 2e-19 69.0 0.6 4.2e-19 68.0 0.4 1.6 1 0 0 1 1 1 1 PUA domain Ima1_N PF09779.4 OAI99997.1 - 2.2e-20 73.5 0.3 2.2e-20 73.5 0.2 2.4 3 0 0 3 3 3 1 Ima1 N-terminal domain FA_desaturase PF00487.19 OAI99997.1 - 2.8 7.2 12.3 0.12 11.8 3.6 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Methyltransf_26 PF13659.1 OAI99998.1 - 7.6e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAI99998.1 - 2.4e-07 30.2 0.0 6.5e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 OAI99998.1 - 0.00012 21.6 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAI99998.1 - 0.0021 18.5 0.0 0.0044 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAI99998.1 - 0.0023 18.7 0.0 0.0097 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAI99998.1 - 0.003 17.9 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M3_N PF08439.5 OAI99998.1 - 0.021 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Oligopeptidase F Methyltransf_11 PF08241.7 OAI99998.1 - 0.03 14.8 0.0 0.069 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.7 OAI99998.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_12 PF08242.7 OAI99998.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nop14 PF04147.7 OAI99999.1 - 3.1 5.6 5.8 6.9 4.4 4.0 1.5 1 0 0 1 1 1 0 Nop14-like family UCR_hinge PF02320.11 OAJ00003.1 - 1.4e-08 34.5 2.2 2.8e-08 33.5 1.5 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein GDNF PF02351.11 OAJ00003.1 - 0.014 15.8 0.8 0.031 14.7 0.6 1.5 1 0 0 1 1 1 0 GDNF/GAS1 domain Sigma70_ner PF04546.8 OAJ00003.1 - 0.3 10.6 8.3 0.38 10.3 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Herpes_LMP2 PF07415.6 OAJ00003.1 - 0.54 8.7 1.8 0.63 8.5 1.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Daxx PF03344.10 OAJ00003.1 - 1.4 7.2 16.2 1.6 7.0 11.2 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 OAJ00003.1 - 2.4 8.4 12.8 4 7.7 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HSP90 PF00183.13 OAJ00003.1 - 2.5 6.3 6.0 2.8 6.2 4.1 1.1 1 0 0 1 1 1 0 Hsp90 protein CDC27 PF09507.5 OAJ00003.1 - 2.8 7.0 11.6 3.2 6.8 8.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 OAJ00003.1 - 2.9 5.6 13.8 3.1 5.6 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family DSBA PF01323.15 OAJ00004.1 - 5e-27 94.7 0.0 6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Formyl_trans_C PF02911.13 OAJ00005.1 - 2.5e-09 37.1 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Formyl_trans_N PF00551.14 OAJ00005.1 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase DUF3515 PF12028.3 OAJ00005.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Abhydrolase_5 PF12695.2 OAJ00006.1 - 8.1e-17 61.3 0.0 1.6e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ00006.1 - 1.5e-16 60.9 0.6 5.1e-16 59.2 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ00006.1 - 5.1e-11 42.2 0.1 1.4e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ00006.1 - 1.6e-05 24.5 1.5 0.0076 15.8 0.9 3.4 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ00006.1 - 0.0037 16.7 0.4 4.6 6.5 0.0 3.0 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Metal_resist PF13801.1 OAJ00006.1 - 0.11 12.5 0.4 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance DUF3292 PF11696.3 OAJ00007.1 - 1.3e-165 551.9 0.3 9.5e-93 311.2 0.0 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Solute_trans_a PF03619.11 OAJ00008.1 - 4.4e-69 232.8 11.9 5.5e-69 232.5 8.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PepSY_TM_2 PF13703.1 OAJ00008.1 - 0.0088 16.1 0.4 0.025 14.7 0.3 1.8 1 0 0 1 1 1 1 PepSY-associated TM helix HLH PF00010.21 OAJ00009.1 - 0.0026 17.4 0.2 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mon1 PF03164.9 OAJ00010.1 - 1.8e-62 211.3 0.0 2.2e-20 72.6 0.0 4.4 5 0 0 5 5 5 4 Trafficking protein Mon1 Dopey_N PF04118.9 OAJ00011.1 - 5.9e-107 357.0 0.0 1.2e-106 356.0 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal MULE PF10551.4 OAJ00014.1 - 1.9e-08 34.3 0.0 5.2e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ00014.1 - 0.041 12.4 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family BUD22 PF09073.5 OAJ00015.1 - 5.8e-24 84.9 37.4 2.2e-23 83.0 25.9 1.8 1 1 0 1 1 1 1 BUD22 Sec5 PF15469.1 OAJ00015.1 - 1.4e-19 70.5 0.2 1.7e-12 47.4 0.0 3.3 3 0 0 3 3 3 2 Exocyst complex component Sec5 BUD22 PF09073.5 OAJ00016.1 - 2.8e-47 161.7 37.3 4.6e-47 161.0 25.9 1.4 1 1 0 1 1 1 1 BUD22 DUF4199 PF13858.1 OAJ00017.1 - 0.21 11.5 0.3 28 4.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Gly-zipper_OmpA PF13436.1 OAJ00017.1 - 1.5 8.5 7.7 0.69 9.5 0.1 2.9 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain PCI PF01399.22 OAJ00018.1 - 1.7e-14 54.0 0.0 4.2e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain zf-Tim10_DDP PF02953.10 OAJ00019.1 - 7.1e-18 63.6 0.8 8.9e-18 63.3 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AdoMet_MTase PF07757.8 OAJ00020.1 - 3.5e-31 107.6 0.1 3.4e-14 52.9 0.1 2.7 3 0 0 3 3 3 2 Predicted AdoMet-dependent methyltransferase Pec_lyase_C PF00544.14 OAJ00020.1 - 2.9e-20 72.5 0.9 4.6e-20 71.9 0.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 OAJ00020.1 - 2.7e-05 23.9 4.4 8e-05 22.4 3.1 1.7 1 1 0 1 1 1 1 Right handed beta helix region Sterol_MT_C PF08498.5 OAJ00021.1 - 7.8e-29 99.4 0.3 8.9e-29 99.2 0.2 1.0 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal HRM PF02793.17 OAJ00021.1 - 0.0012 18.8 0.2 0.0016 18.4 0.1 1.2 1 0 0 1 1 1 1 Hormone receptor domain SSF PF00474.12 OAJ00022.1 - 7e-25 87.4 31.7 7e-25 87.4 22.0 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family CoA_binding_3 PF13727.1 OAJ00022.1 - 0.024 14.4 0.8 0.024 14.4 0.5 3.8 3 1 1 4 4 4 0 CoA-binding domain TFIIA PF03153.8 OAJ00023.1 - 0.65 9.8 7.7 0.79 9.5 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L37e PF01907.14 OAJ00023.1 - 0.7 9.7 9.6 1.4 8.7 6.7 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e zf-CCHC_4 PF14392.1 OAJ00023.1 - 1.9 8.2 10.3 0.24 11.0 0.9 2.6 2 0 0 2 2 2 0 Zinc knuckle MRP-S28 PF10213.4 OAJ00025.1 - 2.2e-24 85.9 0.0 8.7e-24 84.0 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein SR-25 PF10500.4 OAJ00025.1 - 0.49 9.8 12.4 0.78 9.1 8.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubredoxin PF00301.15 OAJ00026.1 - 0.046 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Rubredoxin Raftlin PF15250.1 OAJ00026.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Raftlin UPF0203 PF05254.7 OAJ00027.1 - 3.8e-12 45.8 0.1 3.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) DUF566 PF04484.7 OAJ00027.1 - 0.42 10.0 9.7 0.51 9.7 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 OAJ00027.1 - 5.3 5.1 11.9 6.2 4.9 8.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 OAJ00027.1 - 8.5 4.7 9.9 10 4.5 6.8 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 Surp PF01805.15 OAJ00030.1 - 3.6e-12 45.7 0.4 8.8e-12 44.5 0.2 1.7 2 0 0 2 2 2 1 Surp module RRM_6 PF14259.1 OAJ00030.1 - 2.1e-06 27.6 0.0 6.1e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ00030.1 - 3.2e-05 23.4 0.0 0.28 10.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 OAJ00030.1 - 0.034 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 OAJ00030.1 - 0.2 11.5 0.0 0.57 10.0 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4529 PF15032.1 OAJ00031.1 - 0.14 10.7 0.1 0.2 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) UvrD-helicase PF00580.16 OAJ00032.1 - 4.5e-13 49.1 4.4 7.4e-11 41.8 0.5 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 OAJ00032.1 - 3.1e-12 46.6 0.0 7.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ00032.1 - 3.2e-08 33.3 0.0 0.00013 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 OAJ00032.1 - 5.9e-08 32.7 0.0 1.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 OAJ00032.1 - 1.2e-06 28.2 0.1 0.37 10.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 OAJ00032.1 - 0.00013 21.6 0.0 0.0004 20.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ00032.1 - 0.00091 19.3 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 OAJ00032.1 - 0.085 12.0 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein GatB_N PF02934.10 OAJ00033.1 - 1.3e-83 280.2 0.0 7.4e-83 277.7 0.0 2.1 2 1 0 2 2 2 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 OAJ00033.1 - 4.3e-27 94.6 0.1 3.1e-26 91.8 0.1 2.1 1 1 0 1 1 1 1 GatB domain PMSR PF01625.16 OAJ00034.1 - 2.1e-55 186.8 0.9 2.5e-55 186.6 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Herpes_gE PF02480.11 OAJ00035.1 - 0.14 10.3 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SURF4 PF02077.10 OAJ00036.1 - 4.2e-94 314.8 3.7 4.8e-94 314.6 2.6 1.0 1 0 0 1 1 1 1 SURF4 family Glycogen_syn PF05693.8 OAJ00037.1 - 0 1118.9 0.0 0 1118.7 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 OAJ00037.1 - 1.5e-08 34.2 0.0 7.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 OAJ00037.1 - 1.9e-07 30.8 0.3 6.9e-07 29.0 0.1 2.0 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 OAJ00037.1 - 8.7e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Caleosin PF05042.8 OAJ00038.1 - 6.6e-49 165.7 0.0 8.3e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein ADH_zinc_N PF00107.21 OAJ00039.1 - 5e-29 100.4 0.2 1.1e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ00039.1 - 1.1e-14 55.3 0.8 4e-14 53.6 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ00039.1 - 8.9e-10 38.3 0.2 2.7e-08 33.5 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Rap_GAP PF02145.10 OAJ00040.1 - 5.5e-49 166.1 0.0 1.3e-48 164.8 0.0 1.6 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.3 OAJ00040.1 - 3.1e-42 144.6 0.0 2.5e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 OAJ00040.1 - 1.1e-26 93.7 5.0 1e-24 87.2 3.6 2.9 2 1 0 2 2 2 1 Tuberin Mito_carr PF00153.22 OAJ00041.1 - 8.2e-48 160.0 4.3 1.6e-16 59.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 OAJ00042.1 - 3.4e-17 62.2 0.1 1.6e-14 53.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 OAJ00042.1 - 2.1e-14 53.3 0.1 5.7e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 OAJ00042.1 - 1.2e-12 48.1 0.0 4.2e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain ATP-grasp_2 PF08442.5 OAJ00042.1 - 1.2e-06 28.1 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 OAJ00042.1 - 2.6e-05 23.8 0.0 0.00025 20.6 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.1 OAJ00042.1 - 0.027 13.6 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain TPR_11 PF13414.1 OAJ00046.1 - 5.9e-06 25.8 6.1 0.0017 17.9 0.6 4.5 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 OAJ00046.1 - 3.4e-05 23.2 1.0 3 7.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ00046.1 - 4.6e-05 23.9 7.4 0.34 11.6 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00046.1 - 0.014 15.2 10.5 3.5 7.7 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ00046.1 - 0.27 11.1 5.4 3.9 7.5 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00046.1 - 9.7 7.1 16.3 12 6.8 0.1 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat F-box PF00646.28 OAJ00047.1 - 4.2e-06 26.2 0.1 8.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ00047.1 - 0.0018 17.9 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF465 PF04325.8 OAJ00049.1 - 0.0012 18.4 0.9 0.0018 17.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF465) DUF4515 PF14988.1 OAJ00049.1 - 0.0021 17.7 0.1 0.0022 17.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF4140 PF13600.1 OAJ00049.1 - 0.0086 16.5 0.1 0.0092 16.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 OAJ00049.1 - 0.0089 15.4 0.6 0.01 15.2 0.4 1.3 1 0 0 1 1 1 1 Septum formation initiator Prefoldin_2 PF01920.15 OAJ00049.1 - 0.014 15.1 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit HALZ PF02183.13 OAJ00049.1 - 0.02 14.5 1.2 0.029 14.1 0.8 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper rRNA_proc-arch PF13234.1 OAJ00049.1 - 0.029 13.5 0.4 0.039 13.1 0.3 1.1 1 0 0 1 1 1 0 rRNA-processing arch domain FlaC_arch PF05377.6 OAJ00049.1 - 0.035 13.9 0.2 0.057 13.3 0.2 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.4 OAJ00049.1 - 0.04 13.7 0.2 0.046 13.5 0.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4618 PF15397.1 OAJ00049.1 - 0.04 13.2 0.1 0.044 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Spc24 PF08286.6 OAJ00049.1 - 0.07 12.8 0.4 0.098 12.3 0.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Mito_fiss_reg PF05308.6 OAJ00049.1 - 0.074 12.4 0.2 0.08 12.2 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3573 PF12097.3 OAJ00049.1 - 0.12 10.9 0.5 0.15 10.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2681 PF10883.3 OAJ00049.1 - 0.13 12.5 0.6 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) bZIP_2 PF07716.10 OAJ00049.1 - 0.13 12.0 2.6 0.2 11.5 1.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Tweety PF04906.8 OAJ00049.1 - 0.14 10.5 0.0 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 Tweety TPR_11 PF13414.1 OAJ00050.1 - 1e-08 34.7 0.3 0.00094 18.7 0.0 4.2 4 0 0 4 4 4 3 TPR repeat TPR_12 PF13424.1 OAJ00050.1 - 1.8e-06 27.7 2.4 0.059 13.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00050.1 - 7e-05 22.4 0.7 28 4.9 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ00050.1 - 0.00027 20.4 0.0 0.86 9.3 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ00050.1 - 0.0058 17.2 6.9 45 4.8 0.1 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat F-box PF00646.28 OAJ00052.1 - 0.038 13.6 0.6 0.26 10.9 0.2 2.4 2 0 0 2 2 2 0 F-box domain F-box PF00646.28 OAJ00054.1 - 4.7e-06 26.1 0.1 8.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ00054.1 - 0.0018 17.9 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like ProQ PF04352.8 OAJ00055.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 ProQ/FINO family Cupin_1 PF00190.17 OAJ00056.1 - 6.5e-28 96.9 0.0 7e-14 51.4 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 OAJ00056.1 - 1.7e-27 94.7 0.4 3.1e-15 55.3 0.0 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAJ00056.1 - 8.2e-12 44.9 0.5 1.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAJ00056.1 - 3.2e-08 32.8 0.0 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAJ00056.1 - 4.4e-05 23.1 0.2 0.0036 16.9 0.1 2.5 1 1 1 2 2 2 1 Cupin MannoseP_isomer PF01050.13 OAJ00056.1 - 0.00012 21.7 0.0 0.044 13.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase Cupin_7 PF12973.2 OAJ00056.1 - 0.0031 17.3 0.1 0.58 10.0 0.0 2.8 2 1 0 2 2 2 1 ChrR Cupin-like domain 3-HAO PF06052.7 OAJ00056.1 - 0.026 13.9 0.0 3.2 7.1 0.0 2.4 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase 2OG-FeII_Oxy_5 PF13759.1 OAJ00056.1 - 0.06 13.6 0.1 25 5.2 0.0 3.0 2 2 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase ARD PF03079.9 OAJ00056.1 - 0.12 12.2 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family F-box PF00646.28 OAJ00057.1 - 0.031 13.9 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain DPBB_1 PF03330.13 OAJ00058.1 - 1.8e-05 24.6 0.1 4.7e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel FNIP_N PF14636.1 OAJ00058.1 - 1 9.8 13.3 2.1 8.8 9.2 1.6 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus SpoIIIAH PF12685.2 OAJ00058.1 - 4.3 6.7 13.2 6.5 6.2 9.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein HHV6-IE PF03753.8 OAJ00058.1 - 5 4.4 16.8 6.6 4.0 11.7 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Hid1 PF12722.2 OAJ00058.1 - 6.8 4.2 15.7 8.4 3.9 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Clathrin_propel PF01394.15 OAJ00059.1 - 0.00011 22.2 0.0 0.003 17.7 0.0 3.1 3 0 0 3 3 3 1 Clathrin propeller repeat ABC_tran PF00005.22 OAJ00059.1 - 0.0018 18.5 0.0 0.0064 16.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 OAJ00059.1 - 0.0019 18.0 0.7 0.0056 16.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.1 OAJ00059.1 - 0.015 14.8 0.1 0.055 13.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ00059.1 - 0.086 13.1 1.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain Actino_peptide PF14408.1 OAJ00063.1 - 0.7 9.8 6.9 5.4 7.0 1.4 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in actinomycetes TFIIA PF03153.8 OAJ00065.1 - 2.6 7.8 73.4 0.013 15.3 34.2 2.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Helicase_C PF00271.26 OAJ00066.1 - 8.2e-08 31.9 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ00066.1 - 6.5e-06 25.7 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ00066.1 - 0.011 15.5 0.0 0.12 12.1 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Dmrt1 PF12374.3 OAJ00067.1 - 0.039 14.2 0.5 0.039 14.2 0.3 3.3 2 1 1 3 3 3 0 Double-sex mab3 related transcription factor 1 DEAD PF00270.24 OAJ00071.1 - 4.9e-12 45.6 0.0 9.2e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ00071.1 - 4.5e-10 39.2 0.0 4.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 OAJ00071.1 - 6.8e-07 29.4 0.1 2.8e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ResIII PF04851.10 OAJ00071.1 - 0.12 12.1 0.1 1.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4142 PF13628.1 OAJ00072.1 - 0.024 14.6 3.0 0.039 13.9 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4142) Herpes_UL49_2 PF04823.7 OAJ00072.1 - 0.043 13.7 1.1 0.094 12.6 0.8 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein LPP20 PF02169.11 OAJ00072.1 - 0.054 13.5 0.7 2.6 8.2 1.8 2.2 2 0 0 2 2 2 0 LPP20 lipoprotein Pkinase PF00069.20 OAJ00074.1 - 1.7e-47 161.7 0.0 4.6e-47 160.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00074.1 - 9.1e-24 83.9 0.0 1.6e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00074.1 - 8.3e-08 31.5 0.0 1.2e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ00074.1 - 0.029 14.1 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DnaJ PF00226.26 OAJ00080.1 - 1.7e-16 59.6 0.1 2.9e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DegS PF05384.6 OAJ00080.1 - 0.074 12.2 0.5 0.13 11.4 0.4 1.3 1 0 0 1 1 1 0 Sensor protein DegS Abhydrolase_5 PF12695.2 OAJ00081.1 - 0.0001 22.0 0.0 0.00042 20.1 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ00081.1 - 0.003 17.4 0.2 0.36 10.6 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ00081.1 - 0.02 14.4 0.0 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) DUF915 PF06028.6 OAJ00081.1 - 0.12 11.3 0.0 0.29 10.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Pirin PF02678.11 OAJ00082.1 - 3e-29 101.0 0.0 5.4e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 OAJ00082.1 - 3.9e-23 81.4 0.0 1.7e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 OAJ00082.1 - 0.0061 16.0 1.4 0.028 13.9 0.7 2.2 2 0 0 2 2 2 1 Cupin domain DEAD PF00270.24 OAJ00083.1 - 4.7e-09 35.9 0.0 1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ00083.1 - 0.00086 19.1 0.0 0.0067 16.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 OAJ00083.1 - 0.075 12.7 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.24 OAJ00087.1 - 3e-09 36.6 0.0 6.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ00087.1 - 1.2e-07 31.4 0.0 6.2e-07 29.1 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ00087.1 - 0.00017 21.5 0.1 0.00055 19.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Abhydrolase_5 PF12695.2 OAJ00088.1 - 8.3e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ00088.1 - 0.0036 16.9 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 OAJ00088.1 - 0.021 14.7 0.1 0.36 10.6 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 OAJ00089.1 - 2.1e-28 99.5 0.0 3.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 OAJ00089.1 - 4.5e-15 55.0 0.0 7.6e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ00089.1 - 2e-11 43.6 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ00089.1 - 9.1e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rifin_STEVOR PF02009.11 OAJ00091.1 - 5.6e-05 22.9 0.4 8.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF1191 PF06697.7 OAJ00091.1 - 0.0078 15.0 2.2 0.02 13.7 1.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 OAJ00091.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 OAJ00091.1 - 0.021 14.1 0.6 0.021 14.1 0.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 OAJ00091.1 - 0.021 13.0 2.4 0.061 11.5 0.0 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Gly-zipper_YMGG PF13441.1 OAJ00091.1 - 0.03 13.8 1.1 0.03 13.8 0.7 4.7 5 0 0 5 5 5 0 YMGG-like Gly-zipper EphA2_TM PF14575.1 OAJ00091.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 OAJ00091.1 - 0.12 12.0 0.0 0.12 12.0 0.0 2.8 2 1 1 3 3 3 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 OAJ00091.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ADH_zinc_N_2 PF13602.1 OAJ00092.1 - 4.3e-19 69.6 0.0 1.6e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ00092.1 - 6.5e-14 51.6 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ00092.1 - 5.3e-06 26.1 0.0 2e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RTBV_P12 PF06361.6 OAJ00092.1 - 0.061 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Rice tungro bacilliform virus P12 protein DUF2457 PF10446.4 OAJ00095.1 - 0.069 11.8 9.2 0.086 11.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ00095.1 - 0.85 9.9 4.3 1.7 8.9 3.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_A22B PF04258.8 OAJ00096.1 - 2.2e-70 237.4 6.9 2.8e-70 237.1 4.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 OAJ00096.1 - 5.5e-07 28.9 1.6 1.3e-06 27.7 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) CENP-B_dimeris PF09026.5 OAJ00096.1 - 7.6e-06 26.0 0.9 0.0019 18.4 0.0 2.4 2 0 0 2 2 2 2 Centromere protein B dimerisation domain FAM176 PF14851.1 OAJ00096.1 - 0.029 14.0 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 OAJ00096.1 - 2.4 7.7 7.6 0.3 10.6 0.9 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-C2H2_4 PF13894.1 OAJ00097.1 - 1.7e-09 37.3 6.8 0.00011 22.2 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ00097.1 - 2.9e-09 36.7 5.8 6.1e-06 26.2 0.6 3.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ00097.1 - 8.6e-09 35.2 11.0 0.00036 20.6 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 OAJ00097.1 - 0.0095 16.1 4.5 1.3 9.3 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SR-25 PF10500.4 OAJ00097.1 - 0.32 10.4 14.6 0.052 13.0 5.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-C2H2_jaz PF12171.3 OAJ00097.1 - 0.42 10.8 0.1 0.42 10.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Suf PF05843.9 OAJ00097.1 - 1.3 8.6 20.2 0.19 11.4 11.0 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 OAJ00097.1 - 8.4 3.9 24.5 12 3.4 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 OAJ00098.1 - 2.2e-78 263.8 0.5 1.2e-76 258.1 0.0 3.6 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 OAJ00098.1 - 3.7e-10 39.5 0.4 0.42 11.3 0.0 7.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ00098.1 - 1.4e-06 28.5 0.0 1.3 9.3 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat AKAP95 PF04988.7 OAJ00099.1 - 0.0025 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) HAUS6_N PF14661.1 OAJ00099.1 - 8.5 5.6 11.1 3.2 7.0 4.6 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus RRM_1 PF00076.17 OAJ00100.1 - 2.6e-13 49.4 0.0 4.1e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ00100.1 - 1.5e-10 40.9 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ00100.1 - 2.3e-07 30.5 0.1 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAJ00100.1 - 1e-06 29.0 0.9 1e-06 29.0 0.6 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 OAJ00100.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family Methyltransf_12 PF08242.7 OAJ00101.1 - 3.2e-08 33.9 0.0 8.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ00101.1 - 1.2e-07 31.5 0.0 4.2e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ00101.1 - 3.4e-06 26.5 0.0 5.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ00101.1 - 4.5e-05 23.4 0.1 8.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ00101.1 - 0.001 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ00101.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ00101.1 - 0.0073 16.8 0.0 0.013 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Med12 PF09497.5 OAJ00101.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Methyltransf_11 PF08241.7 OAJ00101.1 - 0.022 15.2 0.0 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Inp1 PF12634.2 OAJ00101.1 - 0.052 13.2 0.5 0.28 10.8 0.4 2.2 2 1 0 2 2 2 0 Inheritance of peroxisomes protein 1 FmrO PF07091.6 OAJ00101.1 - 0.065 12.2 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) HR1 PF02185.11 OAJ00102.1 - 0.00058 19.5 1.6 0.00058 19.5 1.1 1.8 2 1 0 2 2 2 1 Hr1 repeat Adaptin_binding PF10199.4 OAJ00102.1 - 0.1 12.8 1.3 0.12 12.6 0.9 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3708 PF12501.3 OAJ00102.1 - 0.22 11.3 5.2 0.27 11.0 3.6 1.0 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Macoilin PF09726.4 OAJ00102.1 - 0.38 8.9 9.4 0.44 8.7 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Phage_B PF02304.10 OAJ00102.1 - 0.83 9.9 3.7 1.5 9.1 2.6 1.4 1 1 0 1 1 1 0 Scaffold protein B DivIVA PF05103.8 OAJ00102.1 - 7.9 6.5 10.5 13 5.8 7.3 1.4 1 1 0 1 1 1 0 DivIVA protein HlyD PF00529.15 OAJ00102.1 - 8.8 5.5 18.5 10 5.3 12.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DcpS_C PF11969.3 OAJ00103.1 - 3.7e-11 43.2 0.0 1.1e-10 41.7 0.0 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ00103.1 - 2e-06 28.2 0.4 0.019 15.5 0.1 2.5 2 0 0 2 2 2 2 HIT domain COesterase PF00135.23 OAJ00104.1 - 1.6e-65 221.8 0.0 5.4e-65 220.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ00104.1 - 4.8e-14 52.4 0.1 2e-13 50.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ00104.1 - 0.00034 20.3 0.2 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ00104.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 OAJ00104.1 - 0.044 13.1 0.6 0.1 11.9 0.2 1.8 2 0 0 2 2 2 0 Putative esterase DUF533 PF04391.7 OAJ00106.1 - 0.08 12.3 7.1 0.14 11.5 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Apq12 PF12716.2 OAJ00106.1 - 0.3 10.8 2.2 0.71 9.6 1.5 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Rpn3_C PF08375.6 OAJ00107.1 - 1.9e-22 79.3 0.3 7.4e-22 77.5 0.2 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 OAJ00107.1 - 9.6e-18 64.4 0.2 2.5e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 OAJ00107.1 - 0.0018 18.0 1.3 0.0041 16.8 0.1 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 OAJ00107.1 - 0.0091 15.8 2.2 0.1 12.5 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Pkinase PF00069.20 OAJ00109.1 - 1.6e-51 174.9 0.0 1.2e-29 103.2 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00109.1 - 3.5e-21 75.4 0.2 1.7e-13 50.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00109.1 - 1.1e-05 24.6 0.1 0.0098 14.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ00109.1 - 0.0039 16.9 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ00109.1 - 0.059 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SDH_alpha PF03313.10 OAJ00110.1 - 4.6e-93 311.3 0.2 6.9e-93 310.7 0.2 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 OAJ00110.1 - 3.1e-51 173.5 0.0 5.7e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain DUF4218 PF13960.1 OAJ00113.1 - 6.4e-05 22.4 0.5 0.00015 21.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) PCI PF01399.22 OAJ00116.1 - 0.0005 20.3 0.0 0.0012 19.0 0.0 1.7 1 1 0 1 1 1 1 PCI domain DUF3767 PF12597.3 OAJ00117.1 - 1e-29 102.5 0.2 1.3e-29 102.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) XRN_N PF03159.13 OAJ00118.1 - 1.3e-105 352.0 0.0 2.4e-105 351.1 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 OAJ00118.1 - 0.00013 21.7 3.8 0.00033 20.4 2.6 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ00118.1 - 1.2 8.9 3.6 2.3 8.0 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.19 OAJ00119.1 - 3.7e-65 220.2 16.9 8.4e-39 133.3 0.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ00119.1 - 3.7e-17 62.0 43.5 3.5e-14 52.3 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily NDUF_B12 PF08122.7 OAJ00119.1 - 0.14 11.8 0.5 4.4 7.1 0.0 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Dynein_heavy PF03028.10 OAJ00120.1 - 4.5e-167 557.1 0.0 9.8e-167 556.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 OAJ00120.1 - 4.8e-46 156.4 0.4 3.2e-45 153.7 0.0 2.3 2 1 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 OAJ00120.1 - 2.4e-45 154.7 3.8 5.1e-45 153.7 2.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor DUF342 PF03961.8 OAJ00120.1 - 0.72 8.1 15.0 0.81 8.0 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 OAJ00120.1 - 2.1 7.4 6.1 3.5 6.7 0.4 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein IFT46_B_C PF12317.3 OAJ00120.1 - 7.3 5.8 7.9 1.1 8.6 0.1 2.9 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Cyclase PF04199.8 OAJ00122.1 - 8.1e-14 51.6 0.0 1.7e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Putative cyclase FAD_binding_4 PF01565.18 OAJ00123.1 - 5.1e-20 71.3 0.9 1.1e-19 70.2 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ00123.1 - 7.8e-05 22.5 0.3 0.00022 21.0 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3185 PF11381.3 OAJ00123.1 - 0.038 13.7 1.0 1.9 8.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) PepSY_2 PF13670.1 OAJ00123.1 - 0.14 12.1 0.2 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Fork_head PF00250.13 OAJ00124.1 - 2.5e-20 72.2 0.0 2.6e-19 69.0 0.0 2.3 1 1 0 1 1 1 1 Fork head domain Neur_chan_memb PF02932.11 OAJ00124.1 - 5.5 6.7 8.8 0.56 10.0 1.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DASH_Dad3 PF08656.5 OAJ00125.1 - 4.6e-20 71.0 0.2 6.4e-20 70.6 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_60s PF00428.14 OAJ00125.1 - 0.22 11.9 6.3 0.82 10.1 1.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DinB_2 PF12867.2 OAJ00126.1 - 0.0039 17.5 0.1 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 DinB superfamily Rootletin PF15035.1 OAJ00132.1 - 0.024 14.6 3.3 0.033 14.1 2.3 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Metal_resist PF13801.1 OAJ00132.1 - 0.47 10.4 2.5 0.48 10.4 0.1 2.0 2 0 0 2 2 2 0 Heavy-metal resistance mono-CXXC PF15626.1 OAJ00133.1 - 0.66 9.9 4.1 0.41 10.6 0.8 2.1 2 0 0 2 2 2 0 single CXXC unit DUF982 PF06169.7 OAJ00134.1 - 0.055 13.2 0.4 0.082 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) F-box-like PF12937.2 OAJ00135.1 - 0.00099 18.7 1.2 0.0026 17.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ00135.1 - 0.037 13.6 1.3 0.079 12.6 0.4 2.0 2 0 0 2 2 2 0 F-box domain Death PF00531.17 OAJ00136.1 - 0.12 12.2 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 Death domain Pyr_redox_3 PF13738.1 OAJ00137.1 - 1.5e-18 67.6 0.0 3e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ00137.1 - 9.6e-10 37.2 0.2 2.3e-07 29.3 0.2 3.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 OAJ00137.1 - 9.1e-09 35.2 0.3 0.00013 21.8 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ00137.1 - 3.8e-08 33.2 0.0 9.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ00137.1 - 3.5e-06 26.1 0.2 0.00029 19.8 0.0 3.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAJ00137.1 - 1.7e-05 24.7 0.0 0.015 15.1 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ00137.1 - 0.00051 19.0 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ00137.1 - 0.11 11.3 0.1 0.61 8.8 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 OAJ00137.1 - 0.13 11.3 0.1 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.27 OAJ00138.1 - 3.1e-18 64.8 10.4 0.0028 17.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 OAJ00138.1 - 0.00028 20.6 0.0 0.0048 16.6 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Ribophorin_I PF04597.9 OAJ00139.1 - 1.1e-103 347.0 0.0 3e-73 246.7 0.0 2.0 2 0 0 2 2 2 2 Ribophorin I Polysacc_deac_1 PF01522.16 OAJ00140.1 - 9.1e-15 54.3 0.1 2.7e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase MBOAT_2 PF13813.1 OAJ00141.1 - 3.2e-12 46.3 0.3 7e-05 22.8 0.0 2.9 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family Nudix_N PF12535.3 OAJ00142.1 - 0.0014 18.0 0.1 1.3e+02 2.1 0.0 6.3 7 0 0 7 7 7 2 Hydrolase of X-linked nucleoside diphosphate N terminal Lipase_3 PF01764.20 OAJ00143.1 - 1.3e-10 41.0 0.0 6.5e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Colicin_immun PF09204.5 OAJ00143.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity RVT_1 PF00078.22 OAJ00144.1 - 1.8e-33 115.6 0.0 2.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ00144.1 - 3.9e-11 43.4 0.0 7.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 RNase H DBD_Tnp_Mut PF03108.10 OAJ00151.1 - 0.0032 16.9 0.0 0.0057 16.1 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase PMI_typeI PF01238.16 OAJ00151.1 - 0.09 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphomannose isomerase type I MULE PF10551.4 OAJ00152.1 - 1.2e-18 66.9 0.1 2.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ00152.1 - 7.5e-09 35.0 0.1 1.9e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ00152.1 - 9.9e-09 34.2 0.3 2.6e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Transposase, Mutator family zf-CCHC PF00098.18 OAJ00152.1 - 0.0083 16.0 1.8 0.021 14.7 1.2 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ00152.1 - 0.14 11.8 0.7 0.3 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle SWIM PF04434.12 OAJ00152.1 - 0.41 10.1 3.4 5.7 6.5 0.4 2.6 2 0 0 2 2 2 0 SWIM zinc finger Rhodanese PF00581.15 OAJ00158.1 - 7.6e-08 32.7 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain zf-C3HC4 PF00097.20 OAJ00159.1 - 8.1e-06 25.3 0.6 8.1e-06 25.3 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ00159.1 - 1.5e-05 24.9 2.6 1.5e-05 24.9 1.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ00159.1 - 0.00021 20.8 5.4 0.00084 18.9 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ00159.1 - 0.00037 20.2 2.7 0.00037 20.2 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 OAJ00159.1 - 0.00055 19.6 1.7 0.00055 19.6 1.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 OAJ00159.1 - 0.0012 18.7 3.1 0.0012 18.7 2.1 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAJ00159.1 - 0.0014 18.3 4.5 0.0045 16.6 0.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ00159.1 - 0.0015 18.2 3.6 0.0015 18.2 1.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Peptidase_M20 PF01546.23 OAJ00159.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 DUF4243 PF14027.1 OAJ00160.1 - 3.1e-66 224.0 6.8 4.8e-66 223.4 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Metallophos PF00149.23 OAJ00161.1 - 6.6e-07 28.9 0.2 1.5e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRN3 PF05327.6 OAJ00162.1 - 7.7e-130 433.6 0.0 9.9e-128 426.7 0.0 3.2 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 OAJ00162.1 - 0.18 9.6 15.8 0.33 8.8 10.9 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ00162.1 - 1.1 8.2 12.9 2.7 6.9 9.0 1.6 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 OAJ00162.1 - 2.9 6.2 7.4 4.8 5.5 5.1 1.2 1 0 0 1 1 1 0 Daxx Family VitK2_biosynth PF02621.9 OAJ00163.1 - 1.9e-60 204.1 0.0 2.2e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Menaquinone biosynthesis NMT1_2 PF13379.1 OAJ00163.1 - 0.001 18.4 0.2 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.2 OAJ00163.1 - 0.029 13.7 0.1 0.085 12.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein UDPGT PF00201.13 OAJ00164.1 - 1.2e-13 50.4 0.5 2.3e-13 49.5 0.3 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GATA PF00320.22 OAJ00165.1 - 0.0098 15.2 8.6 0.023 14.0 2.3 2.9 2 0 0 2 2 2 2 GATA zinc finger DUF3347 PF11827.3 OAJ00165.1 - 0.78 9.7 5.2 2.4 8.1 3.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) ABC_tran PF00005.22 OAJ00166.1 - 1.5e-47 161.3 0.0 2.4e-27 95.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ00166.1 - 1.9e-37 129.1 18.0 8.2e-17 61.5 9.3 3.8 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ00166.1 - 2.2e-14 54.1 0.3 5e-05 23.4 0.1 4.4 2 2 1 3 3 3 3 AAA domain AAA_23 PF13476.1 OAJ00166.1 - 3e-14 53.8 1.1 3.7e-08 33.9 0.2 3.2 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ00166.1 - 1.4e-10 40.8 7.5 6.9e-05 22.1 0.0 4.4 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ00166.1 - 5.1e-09 35.5 0.2 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 OAJ00166.1 - 2.5e-08 33.1 0.0 0.0021 17.0 0.0 3.3 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF258 PF03193.11 OAJ00166.1 - 4.5e-07 29.1 0.0 0.0077 15.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 OAJ00166.1 - 1.3e-06 27.7 0.0 0.00073 18.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 OAJ00166.1 - 1.6e-06 28.2 6.5 0.013 15.4 0.1 3.6 3 1 0 3 3 3 2 AAA ATPase domain Miro PF08477.8 OAJ00166.1 - 2.8e-06 27.8 0.2 0.035 14.5 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 OAJ00166.1 - 6e-06 25.7 0.0 0.1 12.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 OAJ00166.1 - 1.5e-05 24.8 0.1 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 OAJ00166.1 - 6.9e-05 22.4 0.1 0.1 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA PF00004.24 OAJ00166.1 - 7.5e-05 22.9 0.0 0.65 10.2 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 OAJ00166.1 - 0.00019 20.2 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein AAA_17 PF13207.1 OAJ00166.1 - 0.00023 21.9 0.4 0.54 11.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 OAJ00166.1 - 0.00028 20.6 0.2 0.14 11.8 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ00166.1 - 0.00044 20.4 2.8 0.83 9.8 0.0 4.2 4 1 0 4 4 4 1 AAA domain AAA_33 PF13671.1 OAJ00166.1 - 0.00051 19.9 0.3 1.3 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 OAJ00166.1 - 0.00056 19.8 1.0 0.0018 18.1 0.0 2.2 3 0 0 3 3 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 OAJ00166.1 - 0.0017 18.2 3.5 0.17 11.6 0.8 2.9 2 1 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 OAJ00166.1 - 0.002 17.2 0.0 0.54 9.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 OAJ00166.1 - 0.0022 17.7 0.1 0.09 12.4 0.0 2.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 OAJ00166.1 - 0.003 17.4 0.0 0.49 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 OAJ00166.1 - 0.0039 17.3 0.5 0.83 9.8 0.0 2.9 3 0 0 3 3 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 OAJ00166.1 - 0.0045 16.5 0.1 0.22 10.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 OAJ00166.1 - 0.0048 16.5 1.2 2.1 7.9 0.0 2.9 2 0 0 2 2 2 1 NACHT domain ABC_ATPase PF09818.4 OAJ00166.1 - 0.015 13.8 4.3 0.67 8.4 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 OAJ00166.1 - 0.016 15.4 1.3 2.1 8.6 0.2 2.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ00166.1 - 0.017 15.0 1.1 5.1 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 OAJ00166.1 - 0.019 14.4 0.1 15 5.0 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 OAJ00166.1 - 0.032 13.9 0.2 9.7 5.8 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.1 OAJ00166.1 - 0.042 12.3 0.0 0.082 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 OAJ00166.1 - 0.044 12.7 0.0 3 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 OAJ00166.1 - 0.089 11.6 0.2 13 4.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 OAJ00166.1 - 0.26 10.7 2.3 15 4.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 OAJ00166.1 - 0.43 9.5 0.0 10 4.9 0.0 2.2 2 0 0 2 2 2 0 Septin Rad17 PF03215.10 OAJ00166.1 - 0.53 8.8 0.1 0.98 8.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CFEM PF05730.6 OAJ00167.1 - 0.4 10.5 6.0 0.69 9.7 3.6 1.8 1 1 0 1 1 1 0 CFEM domain DUF566 PF04484.7 OAJ00167.1 - 3.1 7.2 9.6 4.2 6.7 6.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Rad60-SLD PF11976.3 OAJ00168.1 - 1.9e-13 49.8 0.0 1.1e-06 28.2 0.0 4.4 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like Asp_protease_2 PF13650.1 OAJ00168.1 - 3.9e-05 24.0 0.2 0.00085 19.7 0.2 2.9 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00168.1 - 0.0023 17.7 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ00168.1 - 0.047 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease rve PF00665.21 OAJ00169.1 - 1.3e-15 57.5 0.0 3.5e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ00169.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2236 PF09995.4 OAJ00170.1 - 3e-20 72.5 0.8 2.1e-18 66.5 0.1 2.5 2 1 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) Maf PF02545.9 OAJ00171.1 - 1.1e-45 155.1 0.0 1.4e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RNA_pol_Rpb2_6 PF00562.23 OAJ00175.1 - 9.3e-122 406.4 0.0 1.4e-121 405.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ00175.1 - 3.5e-58 195.8 0.3 5.4e-58 195.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ00175.1 - 9.4e-34 116.4 0.1 2.4e-33 115.1 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ00175.1 - 7.5e-26 90.2 0.1 2.2e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ00175.1 - 2.6e-22 78.3 0.3 6.2e-22 77.1 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ00175.1 - 6.5e-21 73.8 0.0 1.7e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ00175.1 - 1.5e-12 47.2 0.4 1.5e-12 47.2 0.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 OAJ00175.1 - 0.0023 16.3 0.1 0.004 15.5 0.0 1.3 1 0 0 1 1 1 1 Baculovirus Y142 protein Chromosome_seg PF13889.1 OAJ00175.1 - 0.071 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Chromosome segregation during meiosis WD40 PF00400.27 OAJ00176.1 - 1.1e-15 56.7 7.4 0.00041 20.1 0.0 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat Mis14 PF08641.7 OAJ00177.1 - 7.6e-07 29.2 5.7 1.3e-06 28.5 4.0 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF4570 PF15134.1 OAJ00177.1 - 0.0085 15.9 8.5 0.009 15.8 4.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4570) Dor1 PF04124.7 OAJ00177.1 - 0.016 13.6 1.6 0.021 13.2 0.3 1.6 1 1 1 2 2 2 0 Dor1-like family YvrJ PF12841.2 OAJ00177.1 - 0.32 10.3 2.1 0.5 9.6 0.5 2.0 2 0 0 2 2 2 0 YvrJ protein family ApoLp-III PF07464.6 OAJ00177.1 - 0.77 9.7 10.0 3.9 7.4 2.6 2.2 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF349 PF03993.7 OAJ00177.1 - 0.84 9.8 6.3 2.4 8.3 4.1 2.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) IncA PF04156.9 OAJ00177.1 - 1.2 8.6 9.8 1.9 8.0 6.8 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 OAJ00177.1 - 1.4 6.7 3.3 1.7 6.3 2.3 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 OAJ00177.1 - 4 5.7 12.2 4.8 5.4 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S8 PF00082.17 OAJ00178.1 - 1.1e-46 159.3 0.0 4.2e-46 157.3 0.0 1.9 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ00178.1 - 4.6e-13 49.5 0.2 1.1e-12 48.3 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ00178.1 - 5.8e-10 38.7 0.2 1.9e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 PA domain UQ_con PF00179.21 OAJ00179.1 - 4.1e-22 78.1 0.0 8.1e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 OAJ00179.1 - 7.3e-05 22.5 1.4 0.00019 21.2 0.9 1.6 1 0 0 1 1 1 1 IBR domain UBA PF00627.26 OAJ00179.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain HEAT PF02985.17 OAJ00180.1 - 0.00042 20.1 8.5 4.1 7.7 0.0 6.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 OAJ00180.1 - 0.0021 18.2 0.0 0.0021 18.2 0.0 4.8 6 0 0 6 6 6 1 HEAT repeats TFIID_20kDa PF03847.8 OAJ00180.1 - 0.5 10.6 3.2 41 4.5 0.0 3.9 5 0 0 5 5 5 0 Transcription initiation factor TFIID subunit A PHD PF00628.24 OAJ00181.1 - 5.2e-07 29.2 13.9 9e-07 28.4 9.6 1.4 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 OAJ00181.1 - 6e-05 23.4 0.0 6e-05 23.4 0.0 4.8 3 2 0 3 3 3 1 SET domain PHD_2 PF13831.1 OAJ00181.1 - 0.31 10.3 5.0 0.57 9.5 3.5 1.4 1 0 0 1 1 1 0 PHD-finger Sec63 PF02889.11 OAJ00182.1 - 1.2e-181 602.9 0.0 1e-98 330.4 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 OAJ00182.1 - 1.6e-45 154.6 0.0 2.3e-27 95.5 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ00182.1 - 1.8e-12 46.9 0.0 9.5e-09 35.0 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ00182.1 - 8.6e-12 45.2 0.0 4.1e-09 36.5 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 OAJ00182.1 - 6.2e-05 23.1 0.0 0.003 17.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ00182.1 - 0.027 13.7 0.0 0.79 8.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Actin PF00022.14 OAJ00183.1 - 4.1e-132 440.3 0.0 4.6e-132 440.1 0.0 1.0 1 0 0 1 1 1 1 Actin CN_hydrolase PF00795.17 OAJ00184.1 - 2.9e-08 33.3 0.0 6.7e-07 28.8 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase UQ_con PF00179.21 OAJ00185.1 - 2.1e-46 156.8 0.0 2.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ00185.1 - 3.1e-06 26.9 0.0 3.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 OAJ00185.1 - 0.008 15.8 0.1 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 OAJ00185.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain Glyco_hydro_cc PF11790.3 OAJ00188.1 - 1.8e-46 158.5 4.1 2.1e-46 158.3 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ThiF PF00899.16 OAJ00189.1 - 1.9e-44 150.7 0.1 1.9e-28 99.0 0.1 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 OAJ00189.1 - 5.6e-43 146.0 0.0 1.4e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 OAJ00189.1 - 1.1e-42 143.4 3.8 3.4e-27 93.8 0.1 3.5 3 0 0 3 3 3 3 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ00189.1 - 4.3e-25 86.8 1.6 3.1e-21 74.4 0.2 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Asp PF00026.18 OAJ00190.1 - 9.1e-55 186.1 1.7 2.1e-54 184.8 1.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ00190.1 - 2.3e-08 33.7 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ00190.1 - 5.1e-08 33.0 2.8 4.6e-07 29.9 0.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ00190.1 - 4e-05 24.0 2.0 0.067 13.7 0.0 2.7 3 0 0 3 3 3 2 Aspartyl protease RNase_T PF00929.19 OAJ00192.1 - 1.2e-18 67.9 0.4 2.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Exonuclease DUF4363 PF14276.1 OAJ00192.1 - 0.082 12.6 0.1 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) PAS_9 PF13426.1 OAJ00192.1 - 0.095 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS domain GATase PF00117.23 OAJ00193.1 - 1.9e-07 30.7 0.0 4.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ00193.1 - 0.014 14.8 0.3 0.043 13.2 0.0 1.9 2 1 0 2 2 2 0 Peptidase C26 Chromate_transp PF02417.10 OAJ00195.1 - 3.2e-51 173.3 35.0 7.6e-29 100.4 7.0 2.6 3 1 0 3 3 3 2 Chromate transporter PFU PF09070.6 OAJ00196.1 - 2.7e-41 140.2 0.0 4.8e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 OAJ00196.1 - 2.4e-38 128.6 12.5 1.9e-07 30.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat PUL PF08324.6 OAJ00196.1 - 2e-36 125.1 0.0 2.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 OAJ00196.1 - 0.0058 16.3 0.0 5.1 6.9 0.0 3.8 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Sugar_tr PF00083.19 OAJ00197.1 - 5.2e-27 94.5 22.7 5e-17 61.6 7.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ00197.1 - 5.9e-12 44.9 47.6 6.2e-08 31.7 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00198.1 - 3.6e-28 98.3 24.2 2.9e-18 65.7 7.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ00198.1 - 8.7e-15 54.2 46.2 2.5e-08 33.0 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily B5 PF03484.10 OAJ00198.1 - 0.072 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase B5 domain Pyr_redox_2 PF07992.9 OAJ00200.1 - 4.8e-21 75.5 6.0 4.7e-20 72.3 4.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 OAJ00200.1 - 6.7e-15 54.4 0.0 1.5e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 OAJ00200.1 - 9.4e-14 51.5 7.6 1.2e-11 44.8 0.2 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ00200.1 - 8e-08 31.9 0.0 3.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ00200.1 - 7.3e-06 26.1 0.6 0.00033 20.7 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ00200.1 - 0.00086 18.3 0.4 0.33 9.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.1 OAJ00200.1 - 0.00091 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_9 PF13454.1 OAJ00200.1 - 0.012 15.3 1.1 0.14 11.9 0.1 2.3 1 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAJ00200.1 - 0.094 11.1 0.0 0.094 11.1 0.0 1.8 3 0 0 3 3 3 0 HI0933-like protein FBPase PF00316.15 OAJ00201.1 - 5.5e-129 429.6 0.0 6e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 OAJ00201.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family DUF605 PF04652.11 OAJ00204.1 - 0.6 9.4 11.3 0.73 9.1 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 OAJ00204.1 - 6.7 4.4 10.2 8.7 4.0 7.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein Polysacc_deac_1 PF01522.16 OAJ00205.1 - 2.5e-26 91.7 0.0 4.2e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ00205.1 - 0.00025 20.0 0.0 0.00035 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 CoA_binding_2 PF13380.1 OAJ00205.1 - 0.084 13.0 0.0 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain DUF930 PF06059.7 OAJ00205.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) GST_N PF02798.15 OAJ00206.1 - 1.9e-13 50.3 0.0 3.3e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ00206.1 - 4.8e-11 42.7 0.0 8.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ00206.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ00206.1 - 3.5e-10 39.7 0.0 5.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ00206.1 - 7.2e-09 35.4 0.1 1.3e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ00206.1 - 5.3e-07 30.0 0.1 9.2e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3220 PF11516.3 OAJ00206.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3120) LRR_6 PF13516.1 OAJ00207.1 - 5.9e-05 22.7 8.3 0.77 10.0 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 OAJ00207.1 - 0.0017 17.8 2.2 14 5.4 0.0 5.2 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 OAJ00207.1 - 0.0037 17.1 5.0 4.8 7.8 0.0 5.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 OAJ00207.1 - 0.041 13.6 8.7 2.3 8.0 0.0 4.8 4 2 2 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 OAJ00207.1 - 0.86 9.8 0.0 0.86 9.8 0.0 5.5 6 1 0 6 6 6 0 Leucine Rich Repeat Med15 PF09606.5 OAJ00208.1 - 4.1 5.4 24.9 4.4 5.3 17.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mito_carr PF00153.22 OAJ00209.1 - 4.5e-64 212.1 1.6 3.5e-21 74.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein His_biosynth PF00977.16 OAJ00210.1 - 1.7e-31 109.2 0.0 2.2e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein MFS_1 PF07690.11 OAJ00211.1 - 5.3e-30 104.3 9.2 5.3e-30 104.3 6.4 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00211.1 - 2.3e-10 39.6 2.1 2.3e-10 39.6 1.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF377 PF04041.8 OAJ00211.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF377) Serglycin PF04360.7 OAJ00211.1 - 0.17 11.5 6.9 0.53 10.0 4.8 1.8 1 0 0 1 1 1 0 Serglycin PBP1_TM PF14812.1 OAJ00211.1 - 6.2 7.1 9.4 26 5.1 6.5 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2HC5 PF06221.8 OAJ00212.1 - 3e-07 30.0 4.9 5e-07 29.3 3.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cyclin_N PF00134.18 OAJ00216.1 - 0.00049 19.6 0.0 0.004 16.7 0.0 2.2 2 1 1 3 3 3 1 Cyclin, N-terminal domain DUF664 PF04978.7 OAJ00216.1 - 0.035 14.3 1.8 0.066 13.4 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF664) GATA PF00320.22 OAJ00217.1 - 0.0001 21.5 2.1 0.00017 20.8 1.5 1.4 1 0 0 1 1 1 1 GATA zinc finger NinG PF05766.7 OAJ00217.1 - 0.18 11.5 0.7 0.49 10.1 0.4 1.6 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein PIF1 PF05970.9 OAJ00218.1 - 2.7e-32 112.1 0.0 7.2e-29 100.8 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00218.1 - 3.4e-07 30.0 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 OAJ00218.1 - 1.1e-05 23.5 0.0 0.046 11.4 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 OAJ00218.1 - 2.7e-05 24.3 0.1 8.5e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ00218.1 - 3.2e-05 23.5 0.4 8.6e-05 22.2 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 OAJ00218.1 - 0.00095 18.4 0.0 0.0023 17.2 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 OAJ00218.1 - 0.0032 16.9 0.2 0.41 10.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Mg_chelatase PF01078.16 OAJ00218.1 - 0.005 16.0 0.1 0.019 14.1 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD-helicase PF00580.16 OAJ00218.1 - 0.012 14.9 0.6 0.024 13.9 0.1 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 OAJ00218.1 - 0.015 14.8 1.2 4.6 6.6 0.3 3.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 OAJ00218.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 OAJ00218.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 OAJ00218.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 OAJ00218.1 - 0.084 12.9 0.3 1.3 9.1 0.2 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 OAJ00218.1 - 0.095 11.6 0.1 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAJ00218.1 - 0.1 12.5 0.2 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ00218.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Arch_ATPase PF01637.13 OAJ00218.1 - 0.13 11.8 0.2 1 9.0 0.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 OAJ00218.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein JmjC PF02373.17 OAJ00219.1 - 0.0006 20.0 0.1 0.0019 18.4 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase IBR PF01485.16 OAJ00219.1 - 0.0053 16.6 1.8 0.013 15.3 1.2 1.6 1 0 0 1 1 1 1 IBR domain Helicase_C PF00271.26 OAJ00221.1 - 6.2e-12 45.2 0.0 1.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ00221.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 OAJ00221.1 - 0.00012 22.2 5.5 0.28 11.6 1.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ00221.1 - 9.1 6.8 12.1 8.4 6.9 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger rve PF00665.21 OAJ00222.1 - 3.1e-17 62.7 0.0 5.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ00222.1 - 3.4e-15 55.4 0.2 6.8e-15 54.4 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 OAJ00222.1 - 0.008 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 OAJ00223.1 - 7e-20 71.3 0.1 1.3e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ00223.1 - 1.2e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ00223.1 - 3.7e-06 27.3 0.0 6.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00223.1 - 9.9e-05 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 OAJ00223.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 Aspartyl protease RVP PF00077.15 OAJ00223.1 - 0.066 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 Retroviral aspartyl protease SoxG PF04268.7 OAJ00223.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Retrotrans_gag PF03732.12 OAJ00224.1 - 5.8e-10 39.1 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ00224.1 - 0.00085 19.1 0.5 0.0016 18.2 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ00224.1 - 0.14 11.8 0.7 0.31 10.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.9 OAJ00225.1 - 3.2e-14 52.3 0.0 6.7e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ00225.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Endonuc-FokI_C PF09254.6 OAJ00225.1 - 0.031 13.3 0.3 0.058 12.4 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal DUF1556 PF07590.6 OAJ00226.1 - 0.48 10.6 5.1 0.92 9.7 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Pkinase PF00069.20 OAJ00227.1 - 3.3e-29 101.8 0.0 4.1e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00227.1 - 8.5e-13 47.9 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00227.1 - 8.6e-06 24.9 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ00227.1 - 0.0011 18.0 0.0 0.0015 17.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ00227.1 - 0.002 17.9 0.3 0.0033 17.1 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family rve PF00665.21 OAJ00232.1 - 9.9e-20 70.8 0.0 7.7e-19 67.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain HTH_28 PF13518.1 OAJ00233.1 - 0.0038 17.2 0.0 0.008 16.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ00233.1 - 0.048 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ00233.1 - 0.076 12.9 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 Transposase Transposase_21 PF02992.9 OAJ00234.1 - 1.2e-18 67.1 0.0 2.4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 PIF1 PF05970.9 OAJ00235.1 - 6.8e-24 84.4 0.1 1.4e-23 83.4 0.0 1.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00235.1 - 6.7e-12 45.3 0.1 2.1e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ00235.1 - 1.8e-07 30.8 0.2 7e-07 28.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ00235.1 - 1.1e-05 25.1 0.0 3.6e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ00235.1 - 0.0084 16.1 1.7 0.017 15.0 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ00235.1 - 0.012 15.7 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Sigma54_activat PF00158.21 OAJ00235.1 - 0.032 13.7 0.0 0.078 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAJ00235.1 - 0.033 14.2 0.1 0.17 11.9 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ00235.1 - 0.071 13.2 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAJ00235.1 - 0.19 11.6 0.0 0.54 10.1 0.0 1.7 1 0 0 1 1 1 0 Torsin BLYB PF05289.6 OAJ00237.1 - 0.17 11.7 0.2 2.3 8.0 0.2 2.3 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein Patched PF02460.13 OAJ00237.1 - 0.7 7.7 0.4 1 7.1 0.3 1.2 1 0 0 1 1 1 0 Patched family NifZ PF04319.8 OAJ00238.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 NifZ domain MaoC_dehydratas PF01575.14 OAJ00239.1 - 5.6e-08 32.1 0.2 7.4e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 MaoC like domain GTP_EFTU PF00009.22 OAJ00240.1 - 1.6e-20 73.3 0.1 1.7e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ00240.1 - 0.00089 19.2 0.2 0.0017 18.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ00240.1 - 0.0012 18.6 1.1 0.45 10.3 0.0 2.1 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 OAJ00240.1 - 0.0087 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Septin Miro PF08477.8 OAJ00240.1 - 0.02 15.3 0.1 0.024 15.1 0.1 1.2 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 OAJ00240.1 - 0.058 12.6 0.3 0.76 8.9 0.2 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 OAJ00240.1 - 0.13 11.4 0.0 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Perilipin PF03036.11 OAJ00247.1 - 0.017 13.9 0.5 0.021 13.6 0.4 1.1 1 0 0 1 1 1 0 Perilipin family Ish1 PF10281.4 OAJ00248.1 - 0.0074 16.3 0.4 24 5.1 0.0 3.6 3 0 0 3 3 3 2 Putative stress-responsive nuclear envelope protein Nop25 PF09805.4 OAJ00248.1 - 0.24 11.4 32.2 0.088 12.8 6.0 4.1 4 0 0 4 4 4 0 Nucleolar protein 12 (25kDa) Prothymosin PF03247.9 OAJ00248.1 - 4.1 7.6 37.0 1.6 8.9 10.4 3.6 3 0 0 3 3 3 0 Prothymosin/parathymosin family Serinc PF03348.10 OAJ00249.1 - 6.4e-143 476.5 5.6 8.3e-143 476.1 3.9 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) NDK PF00334.14 OAJ00250.1 - 3.9e-54 182.0 0.0 4.4e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 OAJ00250.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ DUF2200 PF09966.4 OAJ00252.1 - 0.088 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) HEAT PF02985.17 OAJ00254.1 - 4.5e-06 26.3 3.2 3 8.1 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat Pkinase PF00069.20 OAJ00254.1 - 0.057 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain DUF605 PF04652.11 OAJ00254.1 - 0.41 10.0 17.2 0.61 9.4 11.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF1212 PF06738.7 OAJ00255.1 - 2.5e-33 115.1 15.4 4.5e-33 114.3 1.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 OAJ00255.1 - 2.6e-19 69.4 11.6 2.6e-19 69.4 8.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3815) EcsB PF05975.7 OAJ00255.1 - 2.3 6.5 7.9 0.19 10.1 1.5 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Peptidase_S10 PF00450.17 OAJ00257.1 - 3.1e-92 309.8 0.0 3.9e-92 309.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Arrestin_C PF02752.17 OAJ00258.1 - 9.2e-08 32.2 0.0 3.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ00258.1 - 0.00098 18.9 0.1 0.37 10.5 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain HSP90 PF00183.13 OAJ00259.1 - 5.7e-62 209.8 5.5 1e-31 109.9 0.1 4.0 1 1 3 4 4 4 4 Hsp90 protein DUF1485 PF07364.7 OAJ00259.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Aa_trans PF01490.13 OAJ00262.1 - 1e-81 274.5 33.5 1.2e-81 274.2 23.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sporozoite_P67 PF05642.6 OAJ00262.1 - 0.056 11.3 1.6 0.079 10.8 1.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2890 PF11081.3 OAJ00262.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nucleoplasmin PF03066.10 OAJ00262.1 - 0.12 11.8 3.3 0.19 11.2 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 OAJ00262.1 - 0.59 9.2 2.8 0.85 8.7 1.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 OAJ00262.1 - 2.9 7.0 7.4 4.1 6.5 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 OAJ00262.1 - 3.4 5.4 5.8 4.5 5.0 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2076 PF09849.4 OAJ00263.1 - 7.4e-10 39.2 13.0 8.7e-10 39.0 9.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 OAJ00263.1 - 3.4e-05 23.6 4.8 5.3e-05 23.0 3.3 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 OAJ00263.1 - 0.54 10.0 2.8 11 5.8 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pex14_N PF04695.8 OAJ00263.1 - 2.9 7.9 7.0 2.9 7.9 2.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 OAJ00263.1 - 4.9 6.9 8.1 5.7 6.7 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 OAJ00263.1 - 7.7 4.6 10.7 9.2 4.3 7.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RVT_1 PF00078.22 OAJ00264.1 - 4.6e-16 58.8 0.0 8.5e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00264.1 - 1.3e-06 28.5 0.0 2.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ00264.1 - 2e-05 25.0 0.0 0.00029 21.2 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00264.1 - 0.0041 16.9 0.1 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Reo_sigmaC PF04582.7 OAJ00264.1 - 0.016 14.4 1.6 0.032 13.4 1.1 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein zf-4CXXC_R1 PF10497.4 OAJ00264.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PspA_IM30 PF04012.7 OAJ00264.1 - 0.23 10.7 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.7 OAJ00264.1 - 0.58 9.9 0.0 1.4 8.7 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MULE PF10551.4 OAJ00266.1 - 4.1e-10 39.6 0.4 2.7e-08 33.8 0.1 2.4 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ00266.1 - 0.089 11.3 0.1 0.15 10.5 0.1 1.3 1 0 0 1 1 1 0 Transposase, Mutator family DEAD PF00270.24 OAJ00267.1 - 1.6e-43 148.1 0.0 3.7e-42 143.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ00267.1 - 6.1e-27 93.3 0.2 1.2e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 OAJ00267.1 - 0.017 13.5 0.0 0.03 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Ribosomal_S28e PF01200.13 OAJ00267.1 - 0.047 13.4 0.5 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S28e TPR_11 PF13414.1 OAJ00268.1 - 5.7e-16 57.9 3.3 1.5e-10 40.5 0.2 2.2 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 OAJ00268.1 - 5.3e-10 38.4 0.7 3.3e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00268.1 - 3.9e-08 32.5 0.7 0.00042 20.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00268.1 - 0.00082 19.7 0.2 0.049 14.2 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ00268.1 - 0.0011 18.6 0.0 2.7 8.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ00268.1 - 0.0013 18.6 0.2 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ00268.1 - 0.017 15.4 0.6 0.046 14.0 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ00268.1 - 0.021 14.5 0.3 0.41 10.5 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ00268.1 - 0.021 14.9 0.4 6.7 7.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ00268.1 - 0.031 14.1 0.4 0.092 12.6 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 OAJ00268.1 - 0.039 14.0 0.4 0.19 11.9 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ00268.1 - 0.08 13.6 2.7 0.52 11.0 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat CDC14 PF08045.6 OAJ00269.1 - 3.1e-09 36.3 0.3 0.00059 19.0 0.0 3.1 3 0 0 3 3 3 3 Cell division control protein 14, SIN component zf-CCHC_3 PF13917.1 OAJ00269.1 - 1.3e-08 34.4 4.0 1.4e-08 34.2 1.3 2.3 2 0 0 2 2 2 1 Zinc knuckle Methyltransf_33 PF10017.4 OAJ00271.1 - 3.7e-26 91.4 0.0 9.7e-26 90.1 0.0 1.8 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 OAJ00271.1 - 2.3e-18 66.5 0.2 2.3e-18 66.5 0.1 2.3 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 OAJ00271.1 - 2.9e-06 27.6 1.6 7.5e-06 26.3 0.5 2.1 2 0 0 2 2 2 1 DinB superfamily MFS_1 PF07690.11 OAJ00272.1 - 7e-45 153.2 51.9 7e-45 153.2 36.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ00272.1 - 5.4e-16 57.9 11.9 5.4e-16 57.9 8.2 2.5 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ00272.1 - 4.5e-14 51.8 7.8 4.5e-14 51.8 5.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF544 PF04424.8 OAJ00273.1 - 6.4e-15 55.0 0.0 1.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) PPR PF01535.15 OAJ00280.1 - 1.5e-08 34.0 0.1 0.3 11.1 0.0 4.4 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 OAJ00280.1 - 5.5e-07 29.3 0.5 0.35 11.2 0.0 4.3 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAJ00280.1 - 1.8e-06 27.8 0.0 1.7 8.7 0.0 4.7 5 0 0 5 5 5 2 PPR repeat family PPR_1 PF12854.2 OAJ00280.1 - 0.00032 20.0 0.4 0.047 13.1 0.0 2.7 3 0 0 3 3 3 2 PPR repeat SecE PF00584.15 OAJ00281.1 - 4.2e-14 51.8 0.0 4.7e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Aminotran_1_2 PF00155.16 OAJ00282.1 - 1.5e-36 126.1 0.0 1.6e-35 122.7 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ00282.1 - 0.00012 20.4 0.0 0.00018 19.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3153 PF11353.3 OAJ00282.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Sigma70_ner PF04546.8 OAJ00283.1 - 0.085 12.4 28.7 0.024 14.2 0.9 3.4 3 0 0 3 3 3 0 Sigma-70, non-essential region WD40 PF00400.27 OAJ00284.1 - 5.6e-43 143.3 10.5 1e-08 34.6 0.3 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 OAJ00284.1 - 2.1e-10 40.1 0.7 5.1e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ00284.1 - 2.5e-05 23.7 0.0 6.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain RVT_1 PF00078.22 OAJ00288.1 - 5.8e-20 71.5 0.2 1.6e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00288.1 - 5.8e-15 55.4 0.0 1.5e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ00288.1 - 0.00026 21.4 0.0 0.00079 19.8 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00288.1 - 0.00028 20.7 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Ribosomal_L37e PF01907.14 OAJ00289.1 - 0.14 11.9 1.5 0.26 11.0 1.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L37e adh_short PF00106.20 OAJ00290.1 - 2.2e-63 213.1 11.2 9.9e-32 110.1 2.7 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 OAJ00290.1 - 5.3e-29 100.1 0.0 1.1e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 OAJ00290.1 - 5.9e-29 101.0 6.8 2.7e-14 53.2 1.2 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAJ00290.1 - 7.4e-18 65.1 6.8 9.1e-10 38.7 1.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 OAJ00290.1 - 5.9e-09 35.8 0.0 3.5e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 OAJ00290.1 - 0.00017 20.6 0.4 0.11 11.6 0.1 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 OAJ00290.1 - 0.0017 18.1 2.5 0.78 9.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 OAJ00290.1 - 0.0028 17.3 10.8 0.041 13.5 1.1 2.6 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 OAJ00290.1 - 0.019 14.5 0.4 0.019 14.5 0.3 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF3887 PF13026.1 OAJ00290.1 - 0.074 13.3 0.1 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) DUF543 PF04418.7 OAJ00290.1 - 0.47 10.4 5.9 7.8 6.5 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) RVT_1 PF00078.22 OAJ00292.1 - 2.3e-18 66.3 0.0 4.5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00292.1 - 1.1e-15 57.7 0.0 2.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Phage_integrase PF00589.17 OAJ00295.1 - 2.7e-05 23.8 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ00295.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Abhydrolase_2 PF02230.11 OAJ00299.1 - 3.8e-05 23.2 0.0 5.3e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 OAJ00299.1 - 9.8e-05 22.3 0.4 0.00017 21.5 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family HAP1_N PF04849.8 OAJ00300.1 - 0.0002 20.4 15.8 0.00059 18.8 3.6 3.3 2 1 0 2 2 2 2 HAP1 N-terminal conserved region RhoGEF PF00621.15 OAJ00302.1 - 4.2e-12 46.3 0.0 9.2e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Gln-synt_C PF00120.19 OAJ00303.1 - 3.9e-59 199.9 0.0 4.7e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 OAJ00303.1 - 1.7e-18 65.9 0.0 3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Mob1_phocein PF03637.12 OAJ00304.1 - 1e-21 77.3 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.5 OAJ00304.1 - 0.056 13.4 2.1 0.06 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Spp-24 PF07448.6 OAJ00304.1 - 0.12 12.3 1.1 0.24 11.3 0.7 1.5 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) SR-25 PF10500.4 OAJ00304.1 - 3.6 7.0 8.0 6 6.2 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-LYAR PF08790.6 OAJ00305.1 - 3.5e-11 42.6 1.0 3.5e-11 42.6 0.7 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3133 PF11331.3 OAJ00305.1 - 0.16 11.5 2.1 3.2 7.3 1.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) DUF4449 PF14613.1 OAJ00307.1 - 4.3 7.2 14.7 7.2 6.5 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) tRNA-synt_2b PF00587.20 OAJ00308.1 - 8.1e-44 149.2 0.0 1.6e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ00308.1 - 4.5e-17 61.7 0.3 1e-16 60.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 OAJ00308.1 - 1.1e-12 47.5 0.0 2.8e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 OAJ00308.1 - 1e-10 41.3 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.8 OAJ00308.1 - 0.017 14.8 0.0 0.066 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF502) NTF-like PF14540.1 OAJ00308.1 - 0.12 11.9 0.1 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase-like PTPA PF03095.10 OAJ00309.1 - 8e-86 287.8 0.0 1e-85 287.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1712 PF08217.6 OAJ00310.1 - 0.018 13.3 0.0 0.035 12.3 0.0 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) DUF4611 PF15387.1 OAJ00310.1 - 1.9 8.6 6.8 13 6.0 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Plasmodium_Vir PF05795.6 OAJ00310.1 - 3.4 6.7 4.9 0.55 9.3 0.3 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein zf-U1 PF06220.7 OAJ00311.1 - 1.2 8.7 5.2 19 4.9 1.5 2.2 2 0 0 2 2 2 0 U1 zinc finger gag_pre-integrs PF13976.1 OAJ00315.1 - 5.7e-06 25.8 0.2 8.5e-06 25.3 0.1 1.3 1 1 0 1 1 1 1 GAG-pre-integrase domain Glyco_hydro_63 PF03200.11 OAJ00317.1 - 1.7e-08 32.8 2.4 1.4e-07 29.7 0.3 3.2 2 1 0 2 2 2 1 Mannosyl oligosaccharide glucosidase LMWPc PF01451.16 OAJ00318.1 - 4.2e-34 117.8 0.0 4.7e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Sgf11 PF08209.6 OAJ00319.1 - 9.8e-13 47.1 0.5 9.8e-13 47.1 0.4 2.2 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Ank_2 PF12796.2 OAJ00320.1 - 1.8e-14 53.8 0.0 1.9e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 OAJ00320.1 - 3e-12 46.3 0.2 0.00056 20.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAJ00320.1 - 2.3e-11 43.8 0.0 4.6e-06 27.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ00320.1 - 1.2e-08 34.2 0.2 0.067 13.0 0.0 4.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 OAJ00320.1 - 3.8e-07 29.7 0.6 0.0069 16.5 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeat CobT PF06213.7 OAJ00320.1 - 0.37 9.8 10.1 0.87 8.6 6.3 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 OAJ00320.1 - 2.1 7.5 8.4 2.7 7.1 5.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 OAJ00320.1 - 7 4.4 10.2 7.8 4.2 7.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 OAJ00321.1 - 6.2e-57 193.2 0.7 7.6e-57 192.9 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) SKG6 PF08693.5 OAJ00322.1 - 0.015 14.5 0.1 0.015 14.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Syndecan PF01034.15 OAJ00322.1 - 0.055 13.1 0.1 0.13 11.9 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain Methyltransf_16 PF10294.4 OAJ00323.1 - 2.5e-10 40.0 0.1 0.0001 21.8 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_26 PF13659.1 OAJ00323.1 - 0.039 13.9 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NMT PF01233.14 OAJ00326.1 - 5e-75 250.5 0.0 7.7e-75 249.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 OAJ00326.1 - 3.1e-63 212.5 0.0 7.5e-63 211.3 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 OAJ00326.1 - 0.0015 18.4 0.0 0.0077 16.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ00326.1 - 0.057 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ00326.1 - 0.12 12.4 0.2 2.6 8.1 0.0 2.8 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family Pentapeptide PF00805.17 OAJ00327.1 - 8.3e-26 88.7 4.6 5.8e-08 31.8 0.0 6.9 6 1 1 7 7 7 6 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 OAJ00327.1 - 2.1e-13 49.8 0.0 0.00067 19.4 0.0 4.1 1 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 OAJ00327.1 - 0.024 14.4 0.0 0.61 10.0 0.0 3.1 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) MFS_1 PF07690.11 OAJ00328.1 - 1.4e-30 106.2 20.5 2.2e-30 105.6 14.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PfkB PF00294.19 OAJ00330.1 - 5.3e-58 196.5 0.1 6.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ00330.1 - 0.0009 18.4 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Sec34 PF04136.10 OAJ00331.1 - 0.019 14.6 0.3 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Sec34-like family DUF948 PF06103.6 OAJ00331.1 - 0.033 14.0 4.3 0.64 9.9 0.7 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LXG PF04740.7 OAJ00331.1 - 0.047 13.4 3.0 0.28 10.9 0.1 2.7 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF2636 PF11120.3 OAJ00331.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Snapin_Pallidin PF14712.1 OAJ00331.1 - 0.12 12.7 8.0 0.12 12.7 1.0 3.1 2 1 0 2 2 2 0 Snapin/Pallidin Mnd1 PF03962.10 OAJ00331.1 - 0.54 9.8 5.0 0.2 11.2 1.2 1.9 2 1 1 3 3 3 0 Mnd1 family UQ_con PF00179.21 OAJ00336.1 - 2.3e-49 166.4 0.0 2.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ00336.1 - 1.5e-07 31.2 0.0 6.3e-07 29.2 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B Ribosomal_60s PF00428.14 OAJ00336.1 - 0.045 14.1 2.2 0.064 13.6 1.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acetyltransf_1 PF00583.19 OAJ00337.1 - 4.6e-15 55.4 0.0 6.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ00337.1 - 0.00022 21.3 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ00337.1 - 0.00077 19.1 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ00337.1 - 0.001 18.9 0.1 0.0017 18.1 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ00337.1 - 0.0023 18.0 0.0 0.0043 17.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SspB PF04386.8 OAJ00337.1 - 0.083 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Stringent starvation protein B DUF4219 PF13961.1 OAJ00338.1 - 4.4e-06 25.9 0.1 7.7e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 OAJ00338.1 - 0.05 13.1 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type STE3 PF02076.10 OAJ00338.1 - 0.23 10.5 5.2 0.5 9.4 1.7 2.0 2 0 0 2 2 2 0 Pheromone A receptor Adipogenin PF15202.1 OAJ00338.1 - 2.6 7.9 6.5 5.3 6.9 4.5 1.4 1 0 0 1 1 1 0 Adipogenin Asp PF00026.18 OAJ00339.1 - 3.3e-20 72.5 0.0 4.1e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AAA_5 PF07728.9 OAJ00340.1 - 8.1e-60 200.5 0.0 1.5e-25 89.4 0.0 3.5 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 OAJ00340.1 - 1.6e-06 28.3 0.2 4.3e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_22 PF13401.1 OAJ00340.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ00340.1 - 0.014 15.4 1.7 1.6 8.6 0.0 4.0 3 1 0 4 4 4 0 AAA ATPase domain HI0933_like PF03486.9 OAJ00340.1 - 0.11 10.9 2.2 0.19 10.1 1.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Sec61_beta PF03911.11 OAJ00342.1 - 6.5e-17 61.0 0.3 1e-16 60.3 0.2 1.3 1 0 0 1 1 1 1 Sec61beta family Cyclin_N PF00134.18 OAJ00343.1 - 2.9e-10 39.8 0.0 4.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ00343.1 - 0.014 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat UBN2 PF14223.1 OAJ00344.1 - 0.034 13.9 0.4 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type API5 PF05918.6 OAJ00344.1 - 8.3 4.7 8.3 12 4.2 5.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) UBN2 PF14223.1 OAJ00345.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ00345.1 - 0.023 14.7 0.1 0.051 13.6 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein TelA PF05816.6 OAJ00345.1 - 0.062 11.9 0.2 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) FYVE PF01363.16 OAJ00346.1 - 1.3e-17 63.3 0.1 2.8e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pyr_redox_3 PF13738.1 OAJ00346.1 - 0.063 13.3 0.1 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-DHHC PF01529.15 OAJ00346.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase HypA PF01155.14 OAJ00346.1 - 0.16 11.6 1.0 0.36 10.5 0.7 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S27e PF01667.12 OAJ00346.1 - 2.5 7.7 5.6 3.3 7.3 2.8 2.0 2 0 0 2 2 2 0 Ribosomal protein S27 Prefoldin_2 PF01920.15 OAJ00347.1 - 1.4e-23 82.6 15.6 1.8e-23 82.3 10.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 OAJ00347.1 - 0.0026 17.9 10.4 0.06 13.6 1.3 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Vac_Fusion PF02346.11 OAJ00347.1 - 0.0047 16.3 2.9 0.31 10.5 0.6 2.2 2 0 0 2 2 2 1 Chordopoxvirus fusion protein MAP65_ASE1 PF03999.7 OAJ00347.1 - 0.0066 15.1 4.1 0.0073 14.9 2.8 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Lzipper-MIP1 PF14389.1 OAJ00347.1 - 0.014 15.4 2.2 0.014 15.4 1.6 2.5 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4407 PF14362.1 OAJ00347.1 - 0.017 14.0 0.8 0.017 14.0 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Uds1 PF15456.1 OAJ00347.1 - 0.019 14.9 8.6 0.035 14.1 5.9 1.6 1 1 0 1 1 1 0 Up-regulated During Septation GLYCAM-1 PF05242.6 OAJ00347.1 - 0.022 14.6 3.2 0.028 14.3 2.2 1.2 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Fucose_iso_N2 PF07882.7 OAJ00347.1 - 0.029 14.0 3.4 0.034 13.8 2.3 1.0 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF2205 PF10224.4 OAJ00347.1 - 0.032 13.8 1.9 0.032 13.8 1.3 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Prefoldin_3 PF13758.1 OAJ00347.1 - 0.04 13.6 7.4 0.058 13.1 5.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit VP4_haemagglut PF00426.13 OAJ00347.1 - 0.053 11.4 0.7 0.064 11.2 0.5 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) BRE1 PF08647.6 OAJ00347.1 - 0.056 13.4 13.9 0.53 10.2 2.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.6 OAJ00347.1 - 0.096 11.3 14.4 0.12 11.0 10.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 OAJ00347.1 - 0.099 12.2 15.7 0.21 11.1 10.9 1.5 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 OAJ00347.1 - 0.11 12.4 14.6 0.27 11.1 0.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Mnd1 PF03962.10 OAJ00347.1 - 0.13 11.9 14.9 0.16 11.6 4.3 2.0 1 1 1 2 2 2 0 Mnd1 family DASH_Dam1 PF08653.5 OAJ00347.1 - 0.14 11.9 1.7 3.1 7.6 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF724 PF05266.9 OAJ00347.1 - 0.16 11.5 12.0 0.24 11.0 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seadorna_VP6 PF07407.6 OAJ00347.1 - 0.16 10.6 1.5 0.18 10.5 1.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Cep57_MT_bd PF06657.8 OAJ00347.1 - 0.2 11.6 9.8 17 5.4 6.2 2.9 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 OAJ00347.1 - 0.23 11.1 11.9 1.2 8.9 1.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding KMP11 PF03037.11 OAJ00347.1 - 0.27 11.8 6.8 0.39 11.3 3.5 2.0 1 1 1 2 2 2 0 Kinetoplastid membrane protein 11 Mto2_bdg PF12808.2 OAJ00347.1 - 0.29 11.2 11.1 2.4 8.3 0.1 3.3 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3166 PF11365.3 OAJ00347.1 - 0.31 11.5 5.9 15 6.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) Nup54 PF13874.1 OAJ00347.1 - 0.34 10.5 12.5 0.12 11.9 2.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sas10_Utp3 PF04000.10 OAJ00347.1 - 0.38 10.9 5.3 3.1 8.0 0.1 2.3 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Spc24 PF08286.6 OAJ00347.1 - 0.43 10.2 14.1 1.2 8.8 2.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 OAJ00347.1 - 0.43 9.4 13.7 1.1 8.1 9.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliD_C PF07195.7 OAJ00347.1 - 0.47 9.7 11.0 2.4 7.3 7.6 1.8 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Occludin_ELL PF07303.8 OAJ00347.1 - 0.47 11.2 9.8 2.7 8.7 2.2 2.2 1 1 1 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.7 OAJ00347.1 - 0.49 10.2 6.7 0.8 9.5 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 OAJ00347.1 - 0.59 9.9 17.2 0.5 10.2 4.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc42p PF11544.3 OAJ00347.1 - 0.6 10.0 10.4 1.4 8.8 0.6 2.5 2 1 0 2 2 2 0 Spindle pole body component Spc42p Macoilin PF09726.4 OAJ00347.1 - 0.67 8.1 14.6 0.75 8.0 10.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3073 PF11273.3 OAJ00347.1 - 0.79 10.2 3.7 0.44 11.1 0.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3073) Phlebovirus_NSM PF07246.6 OAJ00347.1 - 0.85 8.7 5.0 1.1 8.3 3.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M GrpE PF01025.14 OAJ00347.1 - 0.97 8.9 13.7 2.6 7.5 1.6 2.1 2 0 0 2 2 2 0 GrpE KxDL PF10241.4 OAJ00347.1 - 0.99 9.3 6.3 0.57 10.1 0.2 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein YgaB PF14182.1 OAJ00347.1 - 1 9.6 11.3 0.42 10.8 2.2 2.3 2 0 0 2 2 2 0 YgaB-like protein APG6 PF04111.7 OAJ00347.1 - 1.1 8.2 16.9 0.17 10.9 5.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 bZIP_1 PF00170.16 OAJ00347.1 - 1.1 9.2 12.1 4.3 7.3 1.4 3.0 2 1 1 3 3 3 0 bZIP transcription factor MIS13 PF08202.6 OAJ00347.1 - 1.1 8.2 8.6 1.4 7.8 6.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Med4 PF10018.4 OAJ00347.1 - 1.2 8.5 8.3 0.28 10.5 0.2 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.2 OAJ00347.1 - 1.2 8.9 18.5 1.6 8.5 11.1 2.1 1 1 0 1 1 1 0 Tropomyosin like CCDC-167 PF15188.1 OAJ00347.1 - 1.4 8.9 7.3 5 7.1 1.2 2.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SlyX PF04102.7 OAJ00347.1 - 1.4 9.3 8.9 0.28 11.6 0.3 2.5 2 1 0 2 2 2 0 SlyX ADIP PF11559.3 OAJ00347.1 - 2 8.3 17.8 2.5 7.9 3.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Seryl_tRNA_N PF02403.17 OAJ00347.1 - 2 8.4 15.2 33 4.5 10.6 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.5 OAJ00347.1 - 2.2 8.1 9.6 5.6 6.8 2.0 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ax_dynein_light PF10211.4 OAJ00347.1 - 2.6 7.8 15.3 0.78 9.5 2.9 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DUF948 PF06103.6 OAJ00347.1 - 2.7 7.9 5.6 1.5 8.7 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.12 OAJ00347.1 - 2.7 7.6 16.1 1.1 8.9 3.4 2.8 1 1 2 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 OAJ00347.1 - 2.8 8.0 13.1 14 5.7 8.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF607 PF04678.8 OAJ00347.1 - 3.4 7.5 8.2 1.3 8.9 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF607 GAS PF13851.1 OAJ00347.1 - 3.7 6.7 20.2 45 3.1 12.6 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 OAJ00347.1 - 3.7 7.3 9.9 3.7 7.3 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 OAJ00347.1 - 3.7 7.3 15.6 20 4.9 10.8 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 OAJ00347.1 - 3.7 7.9 14.1 5.9 7.2 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 OAJ00347.1 - 3.8 5.8 14.6 6.9 5.0 10.2 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_S46 PF10459.4 OAJ00347.1 - 4.3 5.6 10.2 5.2 5.3 7.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3106 PF11304.3 OAJ00347.1 - 4.8 7.6 10.1 0.87 10.0 1.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) Syntaxin_2 PF14523.1 OAJ00347.1 - 4.9 7.2 11.2 0.55 10.3 1.5 2.2 1 1 1 2 2 2 0 Syntaxin-like protein Allexi_40kDa PF05549.6 OAJ00347.1 - 5.8 6.1 6.8 9 5.5 2.8 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.7 OAJ00347.1 - 8 6.2 19.0 16 5.2 8.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Kinetocho_Slk19 PF12709.2 OAJ00347.1 - 8.1 6.5 15.3 3.4 7.8 1.8 3.1 2 2 0 2 2 2 0 Central kinetochore-associated DivIC PF04977.10 OAJ00347.1 - 8.3 5.9 20.3 6.4 6.3 2.3 3.2 2 2 0 2 2 2 0 Septum formation initiator CDC37_N PF03234.9 OAJ00347.1 - 8.6 6.6 12.3 15 5.8 8.5 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Med28 PF11594.3 OAJ00347.1 - 8.7 6.6 10.9 4 7.7 2.5 2.0 1 1 1 2 2 2 0 Mediator complex subunit 28 Fer2 PF00111.22 OAJ00348.1 - 2.1e-11 43.4 0.2 3.2e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 OAJ00348.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 FlgD Ig-like domain TPR_11 PF13414.1 OAJ00349.1 - 2.3e-17 62.4 5.6 9.5e-15 54.0 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 OAJ00349.1 - 6.5e-12 44.5 4.6 0.00036 20.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00349.1 - 2.2e-10 39.6 4.5 0.0011 18.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ00349.1 - 2.3e-06 27.8 0.8 0.0018 18.5 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ00349.1 - 3.2e-05 23.9 2.4 5e-05 23.3 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 OAJ00349.1 - 6e-05 23.6 4.0 0.0036 17.9 0.0 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ00349.1 - 0.00064 19.7 1.5 0.27 11.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00349.1 - 0.0037 17.7 3.6 3.1 8.6 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ00349.1 - 0.011 15.6 2.9 0.029 14.2 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat HHH_8 PF14716.1 OAJ00349.1 - 0.016 15.3 0.6 6.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_6 PF13174.1 OAJ00349.1 - 0.053 14.0 3.3 2.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ00349.1 - 0.073 12.8 1.3 0.78 9.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fer4 PF00037.22 OAJ00350.1 - 4.3e-14 51.4 16.9 1.9e-08 33.5 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 OAJ00350.1 - 2.3e-12 47.0 10.8 3.6e-12 46.4 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAJ00350.1 - 7.6e-10 39.3 7.7 8.7e-05 23.1 0.4 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 OAJ00350.1 - 9e-10 38.2 5.4 7.4e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ00350.1 - 1.5e-09 37.4 22.9 6.8e-08 32.1 8.9 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ00350.1 - 3.2e-09 36.8 11.1 5.8e-09 36.0 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 OAJ00350.1 - 2.7e-08 33.2 14.6 0.0001 21.9 1.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 OAJ00350.1 - 4.3e-08 33.0 20.2 2.4e-05 24.2 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 OAJ00350.1 - 9.9e-08 31.5 18.0 0.00081 19.1 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 OAJ00350.1 - 3.9e-06 26.7 12.3 0.00088 19.4 2.3 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 OAJ00350.1 - 4.2e-06 27.0 9.5 0.00066 19.9 7.4 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAJ00350.1 - 2.7e-05 24.5 9.5 0.016 15.6 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 OAJ00350.1 - 0.00013 22.4 7.0 0.085 13.4 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 OAJ00350.1 - 0.00061 20.1 12.9 0.069 13.5 0.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 OAJ00350.1 - 0.05 14.1 18.1 0.087 13.4 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_11 PF13247.1 OAJ00350.1 - 0.12 12.2 4.1 0.22 11.4 2.8 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.5 OAJ00350.1 - 0.14 12.2 4.4 0.36 10.9 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ALS_ss_C PF10369.4 OAJ00352.1 - 6.2e-21 73.9 0.1 5.6e-19 67.6 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 OAJ00352.1 - 2.2e-12 46.1 0.1 4.7e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 OAJ00352.1 - 6.6e-09 35.4 0.1 2.4e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain Zn_clus PF00172.13 OAJ00353.1 - 3.1e-05 23.7 9.6 5e-05 23.1 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GRP PF07172.6 OAJ00353.1 - 0.0015 18.9 10.6 0.0015 18.9 7.3 4.1 4 1 0 4 4 4 1 Glycine rich protein family Nab2 PF11517.3 OAJ00353.1 - 0.31 11.1 0.0 0.66 10.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Ribosomal_L5_C PF00673.16 OAJ00354.1 - 4.8e-21 74.3 0.0 7.1e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 OAJ00354.1 - 1.3e-19 69.7 0.0 2.9e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Barwin PF00967.12 OAJ00359.1 - 0.014 15.0 0.1 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Barwin family Arf PF00025.16 OAJ00361.1 - 9.4e-37 125.9 0.0 5.2e-25 87.6 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 OAJ00361.1 - 9.7e-13 47.8 0.0 4.6e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 OAJ00361.1 - 6.7e-08 31.9 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ00361.1 - 3.1e-07 30.9 0.0 9.4e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ00361.1 - 3.2e-06 26.4 0.0 4.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ00361.1 - 1.4e-05 23.9 0.0 2.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ00361.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ00361.1 - 0.004 16.9 0.6 0.0084 15.9 0.4 1.5 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.1 OAJ00361.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 OAJ00361.1 - 0.12 11.7 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PIF1 PF05970.9 OAJ00362.1 - 0.0049 15.8 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Sugar_tr PF00083.19 OAJ00363.1 - 3.4e-33 114.9 25.3 1.7e-32 112.5 17.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ00363.1 - 2.7e-17 62.5 55.9 1.7e-13 50.0 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAJ00363.1 - 0.054 12.1 10.4 0.81 8.3 7.2 2.2 1 1 0 1 1 1 0 BT1 family Sugar_tr PF00083.19 OAJ00364.1 - 2.1e-38 132.1 23.8 7.2e-38 130.3 16.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ00364.1 - 1.2e-15 57.1 40.0 7.7e-09 34.7 14.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAJ00364.1 - 2e-05 23.5 0.7 0.07 11.8 0.0 2.4 2 0 0 2 2 2 2 BT1 family MFS_2 PF13347.1 OAJ00364.1 - 0.00024 19.6 22.0 0.0039 15.6 5.0 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein DUF843 PF05814.6 OAJ00364.1 - 0.21 11.4 0.7 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) CENP-B_dimeris PF09026.5 OAJ00365.1 - 0.066 13.4 5.3 0.083 13.1 3.7 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Bac_chlorC PF02043.12 OAJ00365.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Nop14 PF04147.7 OAJ00365.1 - 0.19 9.6 3.0 0.17 9.7 2.1 1.0 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 OAJ00365.1 - 0.29 10.8 3.1 0.36 10.4 2.1 1.2 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 OAJ00365.1 - 0.4 10.2 4.8 0.46 10.0 3.3 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 OAJ00365.1 - 0.42 8.3 6.6 0.44 8.2 4.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.9 OAJ00365.1 - 0.51 8.3 2.4 0.45 8.4 1.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 OAJ00365.1 - 0.69 10.0 6.3 1.2 9.3 4.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2890 PF11081.3 OAJ00365.1 - 0.86 9.6 3.6 1.1 9.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 OAJ00365.1 - 1.9 6.7 7.1 2.1 6.5 4.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 OAJ00365.1 - 2.1 8.6 8.1 3.5 8.0 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Apt1 PF10351.4 OAJ00365.1 - 2.2 7.0 4.3 2.6 6.8 3.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nucleoplasmin PF03066.10 OAJ00365.1 - 6.9 6.1 11.8 9.4 5.7 8.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin CCD PF07860.6 OAJ00366.1 - 0.043 13.2 0.7 0.074 12.5 0.5 1.3 1 0 0 1 1 1 0 WisP family C-Terminal Region Peptidase_S8 PF00082.17 OAJ00368.1 - 5.1e-37 127.5 5.5 9.7e-37 126.6 3.8 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ00368.1 - 1.1e-14 54.7 0.4 6e-14 52.4 0.2 2.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Big_2 PF02368.13 OAJ00368.1 - 0.038 13.8 2.6 0.043 13.7 0.2 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) NPCBM_assoc PF10633.4 OAJ00368.1 - 0.059 13.4 4.9 5.9 7.0 0.0 3.5 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Motile_Sperm PF00635.21 OAJ00368.1 - 0.06 12.9 0.3 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 MSP (Major sperm protein) domain PapD_N PF00345.15 OAJ00368.1 - 0.068 12.9 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF1573 PF07610.6 OAJ00368.1 - 0.17 11.4 2.4 0.72 9.4 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1573) Peptidase_S8 PF00082.17 OAJ00370.1 - 4.6e-80 268.7 0.0 1.6e-41 142.3 0.0 2.7 2 1 0 2 2 2 2 Subtilase family DUF1034 PF06280.7 OAJ00370.1 - 1.6e-27 96.1 3.6 8.7e-13 48.6 0.2 3.0 2 0 0 2 2 2 2 Fn3-like domain (DUF1034) Big_2 PF02368.13 OAJ00370.1 - 8.4e-06 25.5 3.7 0.086 12.7 0.2 3.7 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 2) PapD_N PF00345.15 OAJ00370.1 - 4.9e-05 23.1 0.2 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain Motile_Sperm PF00635.21 OAJ00370.1 - 0.00018 21.1 0.9 0.56 9.8 0.1 2.9 3 0 0 3 3 2 2 MSP (Major sperm protein) domain NPCBM_assoc PF10633.4 OAJ00370.1 - 0.0038 17.2 12.0 10 6.2 0.0 5.5 5 0 0 5 5 5 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Fn3-like PF14310.1 OAJ00370.1 - 0.032 14.1 0.7 23 5.0 0.0 3.7 3 0 0 3 3 3 0 Fibronectin type III-like domain FixG_C PF11614.3 OAJ00370.1 - 0.082 13.0 0.1 10 6.2 0.0 2.8 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase FokI_C PF02980.11 OAJ00370.1 - 0.11 12.1 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain GST_N_2 PF13409.1 OAJ00370.1 - 0.12 12.4 0.2 28 4.8 0.0 2.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF1573 PF07610.6 OAJ00370.1 - 0.3 10.6 9.2 1.4 8.5 0.3 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF1573) MYCBPAP PF14646.1 OAJ00370.1 - 1.3 7.6 0.0 18 3.9 0.0 2.0 2 0 0 2 2 2 0 MYCBP-associated protein family Peptidase_S8 PF00082.17 OAJ00372.1 - 5.5e-37 127.4 0.0 1.7e-36 125.8 0.0 1.8 1 1 0 1 1 1 1 Subtilase family IBN_N PF03810.14 OAJ00373.1 - 4.7e-08 32.8 0.2 0.00018 21.3 0.1 3.6 2 1 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.7 OAJ00373.1 - 0.013 15.4 0.1 0.18 11.6 0.0 2.9 2 1 0 2 2 2 0 Exportin 1-like protein Orbi_VP2 PF00898.12 OAJ00373.1 - 0.77 7.2 0.0 1.1 6.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 IFT57 PF10498.4 OAJ00374.1 - 0.016 14.0 16.0 0.081 11.6 3.6 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BRE1 PF08647.6 OAJ00374.1 - 0.078 12.9 6.3 0.16 11.9 4.4 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Cwf_Cwc_15 PF04889.7 OAJ00374.1 - 1.5 8.4 23.9 2.9 7.5 8.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.2 OAJ00374.1 - 2.1 7.8 14.4 0.79 9.1 4.3 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Bromodomain PF00439.20 OAJ00377.1 - 2.7e-29 100.9 0.8 5.5e-14 51.8 0.1 3.1 2 1 0 2 2 2 2 Bromodomain FlxA PF14282.1 OAJ00377.1 - 0.03 14.2 1.5 0.55 10.2 0.0 2.9 2 0 0 2 2 2 0 FlxA-like protein F-box-like PF12937.2 OAJ00378.1 - 9.4e-09 34.8 1.8 4.1e-08 32.8 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ00378.1 - 7e-06 25.5 0.9 1.2e-05 24.7 0.6 1.4 1 0 0 1 1 1 1 F-box domain CD99L2 PF12301.3 OAJ00378.1 - 4.3 6.9 8.5 0.47 10.1 0.4 2.5 3 0 0 3 3 3 0 CD99 antigen like protein 2 Fungal_trans PF04082.13 OAJ00379.1 - 4.2e-14 52.0 0.0 8e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ00379.1 - 2.2e-08 33.8 8.3 3.6e-08 33.1 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 OAJ00379.1 - 0.0011 16.9 24.4 0.0016 16.4 16.9 1.1 1 0 0 1 1 1 1 Nop14-like family Spore_coat_CotO PF14153.1 OAJ00379.1 - 1.4 8.2 9.5 0.15 11.4 3.3 1.7 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 OAJ00379.1 - 2.2 5.9 1.8 3.1 5.4 1.3 1.1 1 0 0 1 1 1 0 Ycf1 PhzC-PhzF PF02567.11 OAJ00380.1 - 3.1e-39 134.8 0.0 4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 OAJ00380.1 - 0.0024 16.7 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Proline racemase Iso_dh PF00180.15 OAJ00381.1 - 8.2e-101 337.4 0.0 1e-100 337.0 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HsbA PF12296.3 OAJ00382.1 - 5.2e-17 61.8 12.7 5.2e-17 61.8 8.8 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Mannitol_dh PF01232.18 OAJ00382.1 - 0.04 13.8 1.0 0.052 13.4 0.7 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Baculo_PEP_C PF04513.7 OAJ00382.1 - 0.048 13.4 7.7 0.092 12.5 5.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 OAJ00382.1 - 0.06 13.1 0.5 0.69 9.7 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ABC2_membrane_3 PF12698.2 OAJ00382.1 - 0.076 12.0 6.0 0.089 11.8 4.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2202 PF09968.4 OAJ00382.1 - 0.11 12.1 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DivIVA PF05103.8 OAJ00382.1 - 0.11 12.5 0.9 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 DivIVA protein HsbA PF12296.3 OAJ00383.1 - 1.3e-16 60.5 14.4 2.1e-16 59.9 10.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DivIVA PF05103.8 OAJ00383.1 - 0.048 13.6 0.5 0.092 12.8 0.3 1.4 1 0 0 1 1 1 0 DivIVA protein Mannitol_dh PF01232.18 OAJ00383.1 - 0.16 11.8 1.1 0.2 11.5 0.8 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain DUF3713 PF12506.3 OAJ00383.1 - 0.35 10.9 6.8 0.14 12.2 2.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3713) Baculo_PEP_C PF04513.7 OAJ00383.1 - 0.61 9.9 10.0 1.1 9.1 6.9 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUN14 PF04930.10 OAJ00383.1 - 0.78 10.0 3.1 3.9 7.8 2.1 2.3 1 1 0 1 1 1 0 FUN14 family Ribosomal_L28e PF01778.12 OAJ00383.1 - 1.8 9.0 5.0 1.9 8.9 2.1 2.0 1 1 1 2 2 2 0 Ribosomal L28e protein family HsbA PF12296.3 OAJ00384.1 - 3.5e-16 59.1 11.8 3.5e-16 59.1 8.2 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A BRO1 PF03097.13 OAJ00384.1 - 0.033 12.9 1.3 0.04 12.6 0.9 1.1 1 0 0 1 1 1 0 BRO1-like domain FUN14 PF04930.10 OAJ00384.1 - 0.28 11.4 3.0 1.3 9.3 2.1 2.2 1 1 0 1 1 1 0 FUN14 family HsbA PF12296.3 OAJ00385.1 - 1.1e-11 44.6 9.1 1.8e-11 43.9 6.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF2562 PF10814.3 OAJ00385.1 - 0.48 10.3 5.5 0.13 12.1 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) CoaE PF01121.15 OAJ00387.1 - 1.8e-57 193.6 0.0 2.8e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 OAJ00387.1 - 1.6e-06 28.9 0.0 3.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ00387.1 - 0.0015 18.8 0.0 0.016 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 OAJ00387.1 - 0.0024 17.7 0.0 0.017 15.0 0.0 2.3 3 0 0 3 3 3 1 Shikimate kinase AAA_33 PF13671.1 OAJ00387.1 - 0.0036 17.1 0.2 0.03 14.2 0.0 2.5 3 2 0 3 3 3 1 AAA domain DUF4600 PF15372.1 OAJ00388.1 - 0.041 14.1 6.4 0.065 13.4 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Abhydro_lipase PF04083.11 OAJ00389.1 - 5.5e-14 51.2 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 OAJ00389.1 - 9.6e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ00389.1 - 0.026 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HsbA PF12296.3 OAJ00390.1 - 1.2e-15 57.4 11.9 1.9e-15 56.8 8.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Cupin_8 PF13621.1 OAJ00391.1 - 1.6e-27 96.5 0.0 8.2e-27 94.2 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 OAJ00391.1 - 1.9e-09 37.1 0.2 4.7e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 OAJ00391.1 - 6.3e-05 23.1 0.0 0.0035 17.5 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Serglycin PF04360.7 OAJ00395.1 - 0.026 14.2 4.6 0.051 13.2 1.7 2.4 2 0 0 2 2 2 0 Serglycin zf-C2H2 PF00096.21 OAJ00395.1 - 0.13 12.6 0.1 0.13 12.6 0.0 3.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type DUF3246 PF11596.3 OAJ00395.1 - 0.21 10.8 6.0 0.43 9.8 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) tRNA-synt_2b PF00587.20 OAJ00396.1 - 4.4e-34 117.5 0.3 7.4e-34 116.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 OAJ00396.1 - 7.2e-18 64.5 3.4 7.2e-18 64.5 2.4 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.4 OAJ00396.1 - 0.25 10.0 5.6 3.9 6.1 1.1 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 OAJ00396.1 - 1 8.9 6.0 0.55 9.7 2.4 1.7 2 0 0 2 2 2 0 IncA protein Pkinase PF00069.20 OAJ00397.1 - 0.00078 18.6 0.0 0.057 12.5 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00397.1 - 0.003 16.6 0.0 0.22 10.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase TraP PF07296.6 OAJ00397.1 - 0.21 10.5 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 TraP protein Cep57_MT_bd PF06657.8 OAJ00400.1 - 2.4e-12 46.6 2.0 2.4e-12 46.6 1.4 3.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Pkinase PF00069.20 OAJ00401.1 - 2.7e-66 223.3 0.2 5.1e-66 222.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00401.1 - 1.1e-42 145.9 0.6 1.6e-42 145.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 OAJ00401.1 - 3.2e-14 52.7 0.0 9.4e-14 51.2 0.0 1.9 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 OAJ00401.1 - 4.3e-13 48.9 0.0 8.1e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ00401.1 - 2.6e-12 46.7 0.0 5.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 OAJ00401.1 - 3.5e-07 29.4 0.0 0.0027 16.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Nop14 PF04147.7 OAJ00401.1 - 0.21 9.4 7.1 0.37 8.6 4.9 1.3 1 0 0 1 1 1 0 Nop14-like family Seadorna_VP7 PF07387.6 OAJ00401.1 - 0.77 8.5 0.0 1.4 7.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mg_trans_NIPA PF05653.9 OAJ00402.1 - 7.3e-101 337.0 12.9 9.6e-101 336.6 8.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ00402.1 - 1.4e-06 28.4 0.6 1.4e-06 28.4 0.4 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ00402.1 - 0.00033 20.7 24.3 0.001 19.1 3.1 3.0 3 1 0 3 3 3 2 EamA-like transporter family WD40 PF00400.27 OAJ00403.1 - 1.1e-22 78.9 8.3 1.9e-06 27.5 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 OAJ00403.1 - 0.01 15.5 0.3 0.097 12.3 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 OAJ00403.1 - 0.071 12.8 0.3 39 3.8 0.0 3.3 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A E1-E2_ATPase PF00122.15 OAJ00404.1 - 3.4e-52 176.7 3.2 8e-52 175.5 2.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ00404.1 - 1.2e-35 122.6 4.7 1.2e-35 122.6 3.2 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ00404.1 - 5.3e-26 92.3 0.0 7.2e-25 88.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ00404.1 - 8.9e-16 57.1 0.0 1.9e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ00404.1 - 6.6e-15 54.8 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ00404.1 - 6.1e-12 46.1 0.0 2.5e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2556 PF10831.3 OAJ00404.1 - 0.0068 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2556) DUF2157 PF09925.4 OAJ00404.1 - 0.052 13.1 3.0 0.08 12.5 0.2 2.7 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Hydrolase_3 PF08282.7 OAJ00404.1 - 0.28 10.7 0.1 0.66 9.4 0.1 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase URO-D PF01208.12 OAJ00405.1 - 2.7e-129 431.0 0.0 3.1e-129 430.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L11_N PF03946.9 OAJ00406.1 - 2.5e-18 65.2 0.1 4.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ00406.1 - 1.3e-11 44.4 0.1 2.2e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.3 OAJ00406.1 - 0.27 11.3 1.6 0.5 10.5 1.1 1.3 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M DUF2276 PF10040.4 OAJ00408.1 - 0.016 15.4 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2276) GCR1_C PF12550.3 OAJ00408.1 - 0.019 14.8 0.7 0.048 13.5 0.5 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Peptidase_M1 PF01433.15 OAJ00409.1 - 1e-30 107.1 0.0 1.3e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M1 Glu_synthase PF01645.12 OAJ00410.1 - 3.1e-159 529.7 0.0 6.8e-159 528.6 0.0 1.6 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 OAJ00410.1 - 3.9e-139 463.3 0.0 5.3e-139 462.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 OAJ00410.1 - 7.8e-116 386.3 0.0 1.3e-115 385.6 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 OAJ00410.1 - 8.9e-68 227.2 1.7 8.9e-68 227.2 1.2 2.1 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 OAJ00410.1 - 4.5e-23 80.9 0.0 1.2e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 OAJ00410.1 - 1.6e-20 73.8 0.0 1e-19 71.2 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ00410.1 - 2.8e-10 40.6 0.4 6.7e-05 23.0 0.1 2.8 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ00410.1 - 3.7e-09 36.4 0.0 1.5e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ00410.1 - 1.9e-07 31.3 2.2 0.0001 22.6 0.2 3.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAJ00410.1 - 2.3e-07 30.2 0.1 3.9e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 OAJ00410.1 - 2.2e-05 23.7 0.2 5.5e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ00410.1 - 2.3e-05 23.4 2.6 0.00034 19.5 0.2 3.1 2 1 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAJ00410.1 - 5.1e-05 22.8 0.0 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 OAJ00410.1 - 6.4e-05 21.6 0.1 6.4e-05 21.6 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 OAJ00410.1 - 8.1e-05 21.6 0.3 8.1e-05 21.6 0.2 2.3 2 1 0 2 2 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ00410.1 - 0.00042 19.4 0.2 0.00042 19.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DJ-1_PfpI PF01965.19 OAJ00410.1 - 0.00048 19.6 0.0 0.0012 18.2 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family FAD_binding_3 PF01494.14 OAJ00410.1 - 0.0015 17.7 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 OAJ00410.1 - 0.0037 16.1 0.7 0.022 13.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 OAJ00410.1 - 0.011 16.0 1.0 0.61 10.3 0.1 3.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 OAJ00410.1 - 0.012 15.3 0.1 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 OAJ00410.1 - 0.014 14.5 0.1 0.078 12.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GATase_6 PF13522.1 OAJ00410.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMN_dh PF01070.13 OAJ00410.1 - 0.03 13.1 1.7 0.085 11.6 0.8 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase AdoHcyase_NAD PF00670.16 OAJ00410.1 - 0.057 13.2 1.7 14 5.5 0.0 3.3 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 OAJ00410.1 - 0.077 12.8 2.3 0.21 11.4 0.1 2.9 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 OAJ00410.1 - 0.11 12.6 0.1 6.7 6.8 0.0 3.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAJ00410.1 - 0.13 11.1 0.6 6.1 5.6 0.1 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein DUF2334 PF10096.4 OAJ00410.1 - 0.31 10.4 0.1 0.63 9.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) FMO-like PF00743.14 OAJ00410.1 - 0.46 8.6 0.0 1.1 7.4 0.0 1.6 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 OAJ00410.1 - 1 8.9 4.6 0.28 10.7 0.2 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain V-ATPase_H_C PF11698.3 OAJ00411.1 - 8.5e-08 32.1 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H Aminotran_3 PF00202.16 OAJ00412.1 - 7.5e-100 334.0 0.0 9.1e-100 333.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 OAJ00412.1 - 0.00012 21.2 0.0 0.0093 14.9 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Seryl_tRNA_N PF02403.17 OAJ00413.1 - 1.2 9.1 8.3 0.47 10.5 4.0 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DNA_pol_B PF00136.16 OAJ00414.1 - 5.1e-115 384.9 0.0 7.1e-115 384.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 OAJ00414.1 - 7.7e-54 181.9 0.1 1.4e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 OAJ00414.1 - 8.3e-30 103.7 0.0 1.3e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 OAJ00414.1 - 5.7e-22 77.3 7.4 5.7e-22 77.3 5.1 2.2 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Flg_hook PF02120.11 OAJ00415.1 - 0.049 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF3136 PF11334.3 OAJ00415.1 - 0.074 12.4 0.1 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Tetraspannin PF00335.15 OAJ00416.1 - 5.5e-07 29.0 0.2 5.5e-07 29.0 0.1 1.9 1 1 1 2 2 2 1 Tetraspanin family Shisa PF13908.1 OAJ00416.1 - 0.0068 16.6 0.7 0.019 15.1 0.0 2.1 2 1 1 3 3 3 1 Wnt and FGF inhibitory regulator MARVEL PF01284.18 OAJ00416.1 - 0.011 15.5 8.3 0.046 13.5 5.5 2.0 1 1 1 2 2 2 0 Membrane-associating domain Orbi_NS3 PF01616.11 OAJ00416.1 - 0.013 14.5 0.0 1.6 7.6 0.0 2.2 1 1 1 2 2 2 0 Orbivirus NS3 YtpI PF14007.1 OAJ00416.1 - 0.022 14.6 0.1 0.36 10.7 0.0 2.6 2 1 0 2 2 2 0 YtpI-like protein DUF1691 PF07950.6 OAJ00416.1 - 0.069 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) PAP2_3 PF14378.1 OAJ00416.1 - 0.093 12.2 1.2 0.17 11.4 0.9 1.4 1 0 0 1 1 1 0 PAP2 superfamily PalH PF08733.5 OAJ00416.1 - 0.19 10.5 1.3 0.4 9.4 0.5 1.7 1 1 1 2 2 2 0 PalH/RIM21 DUF2207 PF09972.4 OAJ00416.1 - 0.23 9.9 1.7 1.7 7.1 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF998 PF06197.8 OAJ00416.1 - 1.9 7.7 11.0 1.2 8.3 3.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF998) SPRY PF00622.23 OAJ00418.1 - 8e-18 64.7 0.2 1.4e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Dicty_REP PF05086.7 OAJ00418.1 - 7.5 4.1 4.4 10 3.7 3.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BAR PF03114.13 OAJ00419.1 - 7.1e-38 130.3 1.9 1e-37 129.8 1.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 OAJ00419.1 - 2.1e-16 58.9 0.0 3.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ00419.1 - 1.9e-13 49.7 0.0 3.3e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ00419.1 - 2.1e-11 43.1 0.0 3.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.6 OAJ00419.1 - 0.0039 16.5 1.2 0.0057 16.0 0.9 1.2 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.5 OAJ00419.1 - 0.012 14.8 0.4 0.024 13.8 0.3 1.5 1 0 0 1 1 1 0 Vps5 C terminal like BLYB PF05289.6 OAJ00419.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein Hormone_3 PF00159.13 OAJ00419.1 - 0.095 12.7 1.0 0.3 11.1 0.7 1.8 1 0 0 1 1 1 0 Pancreatic hormone peptide Cyclin_N PF00134.18 OAJ00425.1 - 3.6e-18 65.3 0.0 6e-18 64.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ00425.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Baculo_PEP_C PF04513.7 OAJ00426.1 - 0.0013 18.5 1.6 0.2 11.4 0.3 2.1 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 OAJ00426.1 - 0.0015 18.9 0.2 0.0028 18.0 0.1 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.6 OAJ00426.1 - 0.0068 16.7 0.8 1.2 9.5 0.0 2.3 1 1 0 2 2 2 1 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.8 OAJ00426.1 - 0.014 14.7 0.2 0.73 9.1 0.0 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF4164 PF13747.1 OAJ00426.1 - 0.015 15.3 0.3 0.051 13.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Myosin_tail_1 PF01576.14 OAJ00426.1 - 0.028 12.1 0.0 0.033 11.9 0.0 1.1 1 0 0 1 1 1 0 Myosin tail Prominin PF05478.6 OAJ00426.1 - 0.037 11.5 0.1 0.047 11.2 0.1 1.2 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 OAJ00426.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BUD22 PF09073.5 OAJ00431.1 - 0.79 8.7 32.6 0.34 9.9 20.8 1.7 1 1 1 2 2 2 0 BUD22 Nup88 PF10168.4 OAJ00432.1 - 0.11 10.3 0.1 0.13 10.0 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component PIF1 PF05970.9 OAJ00434.1 - 4.3e-20 71.9 0.0 9.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00434.1 - 5.7e-11 42.3 0.0 4.2e-10 39.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ00434.1 - 1.7e-08 34.4 0.0 8.7e-08 32.1 0.0 2.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ00434.1 - 1.1e-07 31.4 3.6 5.9e-07 29.1 0.1 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ00434.1 - 0.0055 16.6 0.4 0.082 12.8 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ00434.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ00434.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ00434.1 - 0.13 11.9 2.0 2 8.1 0.0 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) An_peroxidase PF03098.10 OAJ00436.1 - 1e-75 255.1 0.0 2.4e-73 247.3 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ00436.1 - 2.1e-12 46.3 0.0 3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Cytadhesin_P30 PF07271.6 OAJ00436.1 - 0.15 11.3 1.4 0.26 10.5 1.0 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Pkinase_Tyr PF07714.12 OAJ00437.1 - 0.00088 18.4 0.0 0.078 12.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ00437.1 - 0.0047 16.1 0.0 0.041 13.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Retrotrans_gag PF03732.12 OAJ00438.1 - 0.034 14.2 0.2 0.086 12.9 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein DUF2235 PF09994.4 OAJ00443.1 - 1.8e-62 211.2 0.0 9.7e-62 208.8 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.11 OAJ00444.1 - 3.4e-24 85.9 0.0 4.4e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zn_clus PF00172.13 OAJ00445.1 - 5.2e-07 29.4 9.1 9.5e-07 28.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1762 PF08574.5 OAJ00446.1 - 0.0014 19.0 14.0 0.0014 19.0 9.7 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF1762) Thioesterase PF00975.15 OAJ00447.1 - 7.1e-11 42.7 0.2 1.3e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DCP2 PF05026.8 OAJ00448.1 - 2e-27 94.9 0.1 4.8e-27 93.6 0.1 1.7 1 1 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 OAJ00448.1 - 2.7e-14 52.9 0.1 4.6e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2012 PF09430.5 OAJ00449.1 - 1.3e-21 76.6 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) ORC5_C PF14630.1 OAJ00452.1 - 3e-46 158.0 0.0 6.2e-44 150.4 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus 2_5_RNA_ligase2 PF13563.1 OAJ00454.1 - 5e-18 65.2 2.0 5.4e-17 61.9 0.2 2.4 2 1 0 2 2 2 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 OAJ00454.1 - 1.6e-05 24.7 0.0 0.15 12.0 0.0 3.1 3 0 0 3 3 3 2 LigT like Phosphoesterase CPDase PF07823.6 OAJ00454.1 - 0.0064 16.0 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein Cnd1 PF12717.2 OAJ00455.1 - 6.7e-62 208.4 6.3 1.1e-55 188.3 0.1 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 OAJ00455.1 - 4.1e-42 143.6 0.0 4.1e-42 143.6 0.0 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 OAJ00455.1 - 1.1e-09 38.4 0.2 0.021 15.0 0.0 5.2 5 0 0 5 5 5 2 HEAT repeats Adaptin_N PF01602.15 OAJ00455.1 - 9e-08 30.8 1.1 0.019 13.3 0.1 4.5 4 2 1 5 5 5 3 Adaptin N terminal region HEAT PF02985.17 OAJ00455.1 - 2.7e-07 30.1 2.2 1.1 9.5 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 OAJ00455.1 - 0.0012 19.2 5.8 1.1 9.7 0.0 5.3 5 0 0 5 5 5 2 HEAT-like repeat Cnd3 PF12719.2 OAJ00455.1 - 0.0021 17.1 2.0 0.02 13.8 0.1 3.1 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 OAJ00455.1 - 0.014 15.2 2.7 13 5.7 0.0 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF2435) PqqD PF05402.7 OAJ00455.1 - 0.066 13.2 2.9 1.5 8.8 0.0 4.0 4 1 1 5 5 5 0 Coenzyme PQQ synthesis protein D (PqqD) zf-HIT PF04438.11 OAJ00457.1 - 2.7e-08 33.3 10.7 4.4e-08 32.6 7.4 1.3 1 0 0 1 1 1 1 HIT zinc finger E3_binding PF02817.12 OAJ00457.1 - 0.19 11.4 1.3 7.7 6.2 0.4 2.5 2 0 0 2 2 2 0 e3 binding domain TatD_DNase PF01026.16 OAJ00458.1 - 2.8e-19 69.3 0.3 7.4e-19 67.9 0.2 1.6 1 1 0 1 1 1 1 TatD related DNase TruB_N PF01509.13 OAJ00459.1 - 5.3e-36 124.0 0.0 1.2e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) DKCLD PF08068.7 OAJ00459.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 DKCLD (NUC011) domain Uds1 PF15456.1 OAJ00459.1 - 0.21 11.6 2.8 0.17 11.8 0.8 1.8 2 1 0 2 2 2 0 Up-regulated During Septation Piwi PF02171.12 OAJ00460.1 - 3.7e-12 45.8 0.0 5.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Spt5-NGN PF03439.8 OAJ00461.1 - 8.5e-18 63.8 0.0 2e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 OAJ00461.1 - 1.3e-10 40.5 16.7 0.0059 16.2 0.1 4.9 4 0 0 4 4 4 4 KOW motif Spt5_N PF11942.3 OAJ00461.1 - 1.5e-09 38.3 12.4 1.5e-09 38.3 8.6 2.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Kdo PF06293.9 OAJ00467.1 - 0.16 11.0 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BORG_CEP PF14957.1 OAJ00469.1 - 1.1 10.2 6.4 7 7.5 0.0 2.4 2 0 0 2 2 2 0 Cdc42 effector Dicty_REP PF05086.7 OAJ00469.1 - 4.6 4.8 10.4 6.5 4.3 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cellulase PF00150.13 OAJ00470.1 - 1.6e-05 24.2 0.2 3.4e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Plasmid_Txe PF06769.8 OAJ00470.1 - 0.051 13.4 0.1 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 Plasmid encoded toxin Txe Fungal_trans PF04082.13 OAJ00471.1 - 5.2e-24 84.5 0.0 1.3e-23 83.1 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ00471.1 - 1.5e-09 37.6 10.5 2.6e-09 36.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF1 PF05970.9 OAJ00472.1 - 3.1e-92 309.3 0.0 4.3e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ00472.1 - 4.2e-61 205.8 0.1 1e-60 204.6 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ00472.1 - 4.6e-08 32.8 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ00472.1 - 0.00056 19.9 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Kinesin PF00225.18 OAJ00472.1 - 0.0025 16.5 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF815 PF05673.8 OAJ00472.1 - 0.0079 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 OAJ00472.1 - 0.042 12.4 0.1 0.67 8.5 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 OAJ00472.1 - 0.085 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 OAJ00472.1 - 0.95 8.8 5.1 7.8 5.8 0.2 2.6 2 1 0 3 3 3 0 AAA-like domain Asp PF00026.18 OAJ00475.1 - 2.9e-114 381.5 0.2 3.6e-114 381.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ00475.1 - 4.2e-12 46.3 0.0 8.8e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ00475.1 - 1.8e-06 27.5 0.0 5e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAJ00475.1 - 6.1e-06 26.6 0.1 0.019 15.4 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease F-box-like PF12937.2 OAJ00476.1 - 1.1e-06 28.1 0.0 6.9e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 OAJ00476.1 - 0.0012 18.3 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 F-box domain Lactamase_B_2 PF12706.2 OAJ00477.1 - 1.3e-17 63.9 0.0 6.8e-17 61.6 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAJ00477.1 - 3.6e-08 33.3 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 OAJ00477.1 - 1.7e-05 24.2 0.0 3.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 OAJ00477.1 - 0.056 12.3 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II EGL-1 PF11430.3 OAJ00477.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Programmed cell death activator EGL-1 COesterase PF00135.23 OAJ00478.1 - 5.6e-08 31.9 0.0 1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ00478.1 - 6.2e-07 29.2 0.0 0.0091 15.7 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ00478.1 - 0.00014 21.5 0.0 0.00093 18.8 0.0 2.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ00478.1 - 0.00077 18.7 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family GDH_N PF12466.3 OAJ00478.1 - 0.027 14.4 0.2 0.078 12.9 0.1 1.8 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal VirB3 PF05101.8 OAJ00478.1 - 0.051 13.5 1.1 0.12 12.3 0.8 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Abhydrolase_2 PF02230.11 OAJ00478.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PQ-loop PF04193.9 OAJ00479.1 - 9.1e-25 85.9 6.6 4.4e-16 58.1 0.5 3.5 3 0 0 3 3 3 3 PQ loop repeat NADH-u_ox-rdase PF10785.4 OAJ00479.1 - 0.5 10.6 2.4 0.91 9.8 0.2 2.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Glyco_hydro_47 PF01532.15 OAJ00480.1 - 5.2e-148 493.4 0.0 6e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pet127 PF08634.5 OAJ00483.1 - 5.8e-103 343.7 0.0 7.8e-103 343.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 ATP-synt_C PF00137.16 OAJ00484.1 - 0.0019 18.0 4.2 0.0019 18.0 2.9 1.9 2 0 0 2 2 2 1 ATP synthase subunit C Amb_V_allergen PF03913.8 OAJ00484.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Amb V Allergen DUF89 PF01937.14 OAJ00487.1 - 1.4e-106 356.3 0.0 2.1e-106 355.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function DUF89 FlaE PF07559.9 OAJ00489.1 - 1.7 9.3 10.9 20 5.8 7.5 2.5 1 1 0 1 1 1 0 Flagellar basal body protein FlaE NAD_binding_4 PF07993.7 OAJ00490.1 - 5e-25 87.8 0.0 8.7e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 OAJ00490.1 - 5.4e-19 67.8 0.0 1.6e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 OAJ00490.1 - 6.6e-16 58.4 0.0 1.1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ00490.1 - 0.00011 22.1 0.1 0.0012 18.8 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 OAJ00490.1 - 0.00029 19.6 0.0 0.00057 18.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ00490.1 - 0.0032 17.1 0.0 0.019 14.6 0.0 2.2 1 1 0 1 1 1 1 KR domain Ank_2 PF12796.2 OAJ00492.1 - 6e-37 125.8 5.3 7.4e-12 45.4 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 OAJ00492.1 - 2.8e-34 118.0 7.5 4.5e-34 117.3 5.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank PF00023.25 OAJ00492.1 - 1.3e-33 113.0 14.2 5.5e-09 35.4 0.1 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 OAJ00492.1 - 1.4e-28 98.6 6.7 1.3e-10 41.5 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ00492.1 - 5e-24 83.7 8.7 2.9e-07 30.5 0.1 6.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ00492.1 - 8.1e-22 75.1 5.4 8.1e-05 22.4 0.0 6.3 5 0 0 5 5 5 5 Ankyrin repeat AMP-binding PF00501.23 OAJ00493.1 - 7.7e-21 73.9 0.2 4.9e-19 68.0 0.1 2.3 2 1 0 2 2 2 2 AMP-binding enzyme YqjK PF13997.1 OAJ00493.1 - 0.15 12.2 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 YqjK-like protein UCH PF00443.24 OAJ00494.1 - 2.5e-48 164.5 0.0 9.7e-48 162.5 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ00494.1 - 1.2e-24 87.3 0.6 3.2e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UDPGT PF00201.13 OAJ00496.1 - 5.5e-13 48.2 0.2 8.7e-13 47.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PAN_4 PF14295.1 OAJ00499.1 - 0.0018 17.9 0.7 0.0037 16.9 0.5 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 OAJ00504.1 - 0.00055 19.5 1.3 0.0012 18.5 0.9 1.5 1 0 0 1 1 1 1 PAN domain DUF3316 PF11777.3 OAJ00504.1 - 1.8 8.3 7.6 0.07 12.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Lipase_GDSL PF00657.17 OAJ00505.1 - 4.1e-10 39.8 0.0 5.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAJ00505.1 - 2.6e-06 27.7 1.2 8.1e-06 26.0 0.9 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box PF00646.28 OAJ00508.1 - 0.012 15.1 0.2 0.086 12.5 0.1 2.5 2 0 0 2 2 2 0 F-box domain DED PF01335.16 OAJ00508.1 - 3.9 7.6 8.1 0.68 10.0 0.6 3.2 3 0 0 3 3 3 0 Death effector domain Retrotrans_gag PF03732.12 OAJ00509.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.22 OAJ00510.1 - 4.2e-19 68.7 0.0 8.5e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00510.1 - 8.2e-18 64.6 0.0 2.1e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.9 OAJ00510.1 - 1.1e-11 44.1 0.0 2.5e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Asp_protease_2 PF13650.1 OAJ00510.1 - 0.00015 22.1 0.1 0.00054 20.4 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00510.1 - 0.22 11.4 0.0 0.59 10.0 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 OAJ00511.1 - 1.9e-48 164.9 0.0 7e-47 159.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00511.1 - 8.7e-26 90.5 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ00511.1 - 0.00059 19.6 0.0 0.055 13.1 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ00511.1 - 0.0022 17.0 0.0 0.0046 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 OAJ00511.1 - 0.37 10.3 0.0 0.63 9.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Mitofilin PF09731.4 OAJ00512.1 - 0.00027 19.7 7.7 0.00027 19.7 5.3 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein CAF-1_p150 PF11600.3 OAJ00512.1 - 0.00039 19.8 18.0 0.00054 19.4 12.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3708 PF12501.3 OAJ00512.1 - 0.023 14.5 0.8 0.04 13.7 0.6 1.5 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Peptidase_M29 PF02073.10 OAJ00512.1 - 0.053 12.2 5.3 0.064 12.0 3.7 1.1 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Prominin PF05478.6 OAJ00512.1 - 0.065 10.7 2.1 0.086 10.3 1.5 1.2 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 OAJ00512.1 - 0.08 12.4 17.5 0.17 11.3 12.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Mononeg_RNA_pol PF00946.14 OAJ00512.1 - 0.17 9.2 2.1 0.2 9.0 1.5 1.0 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase Borrelia_P83 PF05262.6 OAJ00512.1 - 0.23 9.7 18.5 0.3 9.2 12.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FPN1 PF06963.7 OAJ00512.1 - 0.28 9.5 3.0 0.44 8.8 2.1 1.3 1 1 0 1 1 1 0 Ferroportin1 (FPN1) DUF3810 PF12725.2 OAJ00512.1 - 0.34 9.7 2.9 0.44 9.4 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RR_TM4-6 PF06459.7 OAJ00512.1 - 0.52 10.1 11.9 0.68 9.7 8.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.15 OAJ00512.1 - 0.61 7.9 11.8 0.74 7.6 8.2 1.0 1 0 0 1 1 1 0 Hsp70 protein GAGA_bind PF06217.7 OAJ00512.1 - 0.86 9.5 13.1 1.1 9.1 9.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.8 OAJ00512.1 - 0.99 8.5 16.8 1.3 8.1 11.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ycf1 PF05758.7 OAJ00512.1 - 1.1 6.8 14.1 1.4 6.5 9.8 1.0 1 0 0 1 1 1 0 Ycf1 PA26 PF04636.8 OAJ00512.1 - 1.2 7.7 6.8 1.5 7.4 4.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.11 OAJ00512.1 - 1.4 7.4 4.8 1.6 7.2 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 OAJ00512.1 - 1.7 8.1 15.2 3.8 7.0 10.5 1.5 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 OAJ00512.1 - 1.8 7.5 4.8 2.2 7.2 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein SAPS PF04499.10 OAJ00512.1 - 1.8 7.1 7.5 2 6.9 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Atg14 PF10186.4 OAJ00512.1 - 1.9 7.3 13.6 2.5 6.9 9.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ApoO PF09769.4 OAJ00512.1 - 2.3 7.8 8.2 13 5.4 5.7 2.0 1 1 0 1 1 1 0 Apolipoprotein O V_ATPase_I PF01496.14 OAJ00512.1 - 2.6 5.8 5.2 3 5.5 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRF PF01765.14 OAJ00512.1 - 3.7 7.0 16.2 4.1 6.8 9.9 2.0 2 1 0 2 2 2 0 Ribosome recycling factor HAUS6_N PF14661.1 OAJ00512.1 - 4 6.7 12.9 5.3 6.3 8.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Phasin PF05597.6 OAJ00512.1 - 6.2 6.5 19.3 4.5 7.0 7.8 2.7 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Hormone_1 PF00103.15 OAJ00512.1 - 7 5.9 9.5 40 3.4 0.4 2.0 1 1 1 2 2 2 0 Somatotropin hormone family OmpH PF03938.9 OAJ00512.1 - 7.9 6.3 19.8 12 5.7 13.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 OAJ00512.1 - 8.9 6.7 30.3 0.099 13.0 3.5 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Zw10 PF06248.8 OAJ00513.1 - 0.0032 15.6 1.3 0.013 13.6 0.0 2.3 3 0 0 3 3 3 1 Centromere/kinetochore Zw10 PseudoU_synth_1 PF01416.15 OAJ00514.1 - 1.2e-17 64.2 0.0 6e-08 33.0 0.0 3.0 2 1 0 2 2 2 2 tRNA pseudouridine synthase GST_N_3 PF13417.1 OAJ00515.1 - 1.9e-05 24.7 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ00515.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ00515.1 - 0.013 15.3 0.0 0.083 12.7 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MCM PF00493.18 OAJ00518.1 - 1.5e-131 438.1 0.0 3.4e-131 436.9 0.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 OAJ00518.1 - 1.3e-26 93.4 0.0 3.8e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ00518.1 - 1.9e-07 30.9 0.0 2.6e-05 23.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ00518.1 - 7.1e-07 28.5 0.0 5e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 OAJ00518.1 - 0.0029 17.9 0.2 0.0084 16.4 0.2 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ00518.1 - 0.027 14.0 0.0 0.086 12.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thiolase_C PF02803.13 OAJ00519.1 - 1.1e-11 44.1 1.0 5.8e-11 41.8 0.2 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 OAJ00519.1 - 4.1e-08 32.5 1.1 6.4e-07 28.6 0.0 2.6 3 1 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 OAJ00519.1 - 0.0047 16.7 0.9 0.037 13.8 0.1 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 OAJ00519.1 - 0.021 14.4 1.5 0.32 10.6 0.3 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 OAJ00519.1 - 0.062 12.7 4.7 0.75 9.2 1.0 2.4 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain zf-C2H2 PF00096.21 OAJ00520.1 - 2.2e-20 71.6 67.5 0.028 14.7 1.4 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ00520.1 - 1.6e-18 65.5 62.0 0.026 14.8 2.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ00520.1 - 4.3e-06 26.7 4.6 0.00033 20.7 0.0 12.6 15 0 0 15 15 15 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ00520.1 - 8.4e-05 22.5 21.6 3.5 7.8 0.0 8.0 8 0 0 8 8 8 2 Zinc-finger double-stranded RNA-binding Rep_4 PF05797.6 OAJ00520.1 - 0.068 11.8 0.0 0.068 11.8 0.0 2.3 3 0 0 3 3 3 0 Yeast trans-acting factor (REP1/REP2) Sigma70_ner PF04546.8 OAJ00520.1 - 3.3 7.2 24.0 1.7 8.2 2.9 4.0 4 0 0 4 4 4 0 Sigma-70, non-essential region MULE PF10551.4 OAJ00521.1 - 2.6e-08 33.8 0.4 3e-07 30.5 0.1 2.7 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ00521.1 - 0.00017 20.9 1.2 0.00059 19.2 0.9 1.9 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.10 OAJ00521.1 - 0.1 13.1 0.1 0.44 11.0 0.0 2.0 2 0 0 2 2 2 0 FAR1 DNA-binding domain DUF1741 PF08427.5 OAJ00523.1 - 1.9e-10 40.6 2.0 0.00051 19.5 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF1741) Hexokinase_1 PF00349.16 OAJ00524.1 - 5.5e-64 215.2 0.0 7.7e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 OAJ00524.1 - 4.9e-61 206.0 0.1 1.3e-44 152.2 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Het-C PF07217.6 OAJ00526.1 - 9.3e-107 357.6 0.0 1.1e-106 357.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ATP_bind_3 PF01171.15 OAJ00527.1 - 1.2e-15 57.5 0.0 2.1e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 PP-loop family RecR PF02132.10 OAJ00527.1 - 0.0046 16.3 1.3 0.0046 16.3 0.9 2.9 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 OAJ00527.1 - 0.043 12.3 0.0 0.066 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 OAJ00527.1 - 0.35 10.2 10.5 0.097 12.0 0.3 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding DZR PF12773.2 OAJ00527.1 - 1.2 8.9 10.5 2.7 7.8 0.4 3.2 3 0 0 3 3 3 0 Double zinc ribbon RVT_2 PF07727.9 OAJ00528.1 - 1.2e-74 250.3 0.0 2.1e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00528.1 - 1.1e-18 67.4 0.1 1.1e-17 64.2 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ00528.1 - 1.5e-13 50.3 0.0 2.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ00528.1 - 5.6e-06 26.1 0.0 9.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ00528.1 - 0.00029 20.4 0.0 0.00072 19.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.1 OAJ00528.1 - 0.013 14.9 0.4 0.029 13.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 OAJ00528.1 - 0.016 15.1 7.0 0.034 14.0 4.9 1.6 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.1 OAJ00528.1 - 0.073 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RVT_3 PF13456.1 OAJ00528.1 - 0.074 12.8 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Reverse transcriptase-like RVP PF00077.15 OAJ00528.1 - 0.11 12.4 0.1 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Retroviral aspartyl protease Cbl_N PF02262.11 OAJ00528.1 - 0.46 10.1 0.0 0.86 9.3 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 NAD_binding_1 PF00175.16 OAJ00530.1 - 9.3e-27 93.7 0.0 1.7e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 OAJ00530.1 - 9e-19 67.4 0.0 2.7e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAJ00530.1 - 8.1e-08 32.3 0.0 5e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAJ00530.1 - 0.0053 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain T2SE PF00437.15 OAJ00531.1 - 3.6e-05 22.8 0.0 3.6e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAJ00531.1 - 0.0034 16.8 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 OAJ00531.1 - 0.029 13.0 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit KaiC PF06745.8 OAJ00531.1 - 0.034 13.2 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 KaiC DEAD PF00270.24 OAJ00531.1 - 0.039 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.1 OAJ00531.1 - 0.043 13.3 0.0 0.095 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 OAJ00531.1 - 0.051 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 OAJ00531.1 - 0.063 12.5 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 OAJ00531.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 OAJ00531.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter F-box-like PF12937.2 OAJ00535.1 - 0.0041 16.8 0.2 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like PS_Dcarbxylase PF02666.10 OAJ00536.1 - 9.1e-49 165.4 0.0 1.4e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 OAJ00536.1 - 1.6e-28 98.3 0.0 3.2e-14 52.5 0.0 3.8 3 0 0 3 3 3 3 C2 domain EF-hand_6 PF13405.1 OAJ00536.1 - 0.0027 17.4 0.2 0.0077 16.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain Nop14 PF04147.7 OAJ00536.1 - 0.084 10.7 30.5 0.17 9.7 21.1 1.4 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 OAJ00536.1 - 0.19 9.7 3.7 0.28 9.2 2.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAPS PF04499.10 OAJ00536.1 - 0.44 9.1 2.3 0.7 8.4 1.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 OAJ00536.1 - 0.71 7.5 1.8 1.1 6.8 1.2 1.3 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 OAJ00536.1 - 7.7 6.3 13.4 6.4 6.5 4.9 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.2 OAJ00537.1 - 0.0033 17.1 0.3 0.0091 15.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like RVT_2 PF07727.9 OAJ00538.1 - 1.2e-86 289.6 0.0 1.7e-86 289.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00538.1 - 6.4e-21 74.6 0.4 2.1e-20 73.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 OAJ00538.1 - 1.6e-06 27.8 0.0 6.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ00538.1 - 2.2e-05 24.0 0.1 5.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ00538.1 - 0.00014 21.5 3.7 0.00017 21.3 1.0 2.3 2 0 0 2 2 2 1 Zinc knuckle rve_3 PF13683.1 OAJ00538.1 - 0.0017 17.8 0.3 0.013 14.9 0.2 2.6 1 1 0 1 1 1 1 Integrase core domain zf-CCHC_5 PF14787.1 OAJ00538.1 - 0.003 17.0 0.8 0.007 15.8 0.1 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger RVP PF00077.15 OAJ00538.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease TPR_12 PF13424.1 OAJ00539.1 - 0.0021 17.9 4.4 4.8 7.1 0.2 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ00539.1 - 0.044 14.2 1.9 31 5.3 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ00539.1 - 0.045 13.6 6.2 0.49 10.4 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00539.1 - 0.058 14.0 5.8 21 6.1 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat PCI PF01399.22 OAJ00543.1 - 0.0039 17.4 0.0 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain F-box PF00646.28 OAJ00544.1 - 8.8e-09 34.8 1.8 2.3e-08 33.4 1.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ00544.1 - 0.0054 16.4 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 OAJ00544.1 - 0.083 12.6 0.4 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 OAJ00545.1 - 0.035 13.7 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 F-box domain Mcp5_PH PF12814.2 OAJ00545.1 - 0.095 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Glycos_transf_1 PF00534.15 OAJ00547.1 - 3.6e-24 85.0 0.0 6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 OAJ00547.1 - 1.2e-23 83.3 0.6 2.2e-20 72.7 0.5 2.5 1 1 1 2 2 2 2 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.1 OAJ00547.1 - 8.1e-16 58.2 2.0 5.2e-15 55.5 1.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 OAJ00547.1 - 5e-12 46.1 0.1 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ00547.1 - 1.1e-07 32.1 3.2 1.3e-06 28.6 0.3 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 OAJ00547.1 - 3.4e-06 27.2 0.0 1.1e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAJ00547.1 - 0.021 14.6 0.1 0.064 13.0 0.1 1.8 1 1 0 1 1 1 0 Glycosyl transferase 4-like ubiquitin PF00240.18 OAJ00548.1 - 2.7e-19 68.3 0.1 4.1e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 OAJ00548.1 - 8.6e-13 47.7 1.6 1.1e-06 28.2 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 OAJ00548.1 - 1.4e-12 46.8 13.1 2.8e-12 45.9 9.1 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 OAJ00548.1 - 9.1e-08 31.6 0.1 1.5e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 OAJ00548.1 - 0.0091 15.8 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 OAJ00548.1 - 0.044 13.3 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain CSTF2_hinge PF14327.1 OAJ00548.1 - 0.066 13.2 6.3 0.33 11.0 4.1 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RAP1 PF07218.6 OAJ00548.1 - 2.5 6.0 3.8 3.4 5.6 2.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box PF00646.28 OAJ00549.1 - 2.9e-10 39.5 0.3 5.4e-10 38.6 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ00549.1 - 9.5e-05 22.0 0.1 0.00018 21.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ00549.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain p47_phox_C PF08944.6 OAJ00549.1 - 0.42 10.8 3.6 6.9 6.9 0.1 2.6 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Pkinase PF00069.20 OAJ00550.1 - 2e-73 246.7 0.0 2.5e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00550.1 - 3.1e-31 108.4 0.0 4.7e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00550.1 - 7.8e-07 28.3 0.4 0.0018 17.2 0.1 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 OAJ00550.1 - 0.001 18.4 0.2 0.0016 17.7 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 OAJ00550.1 - 0.03 14.0 1.5 0.074 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family SEEEED PF14797.1 OAJ00550.1 - 5.8 7.0 9.5 8.2 6.5 6.6 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex F-box PF00646.28 OAJ00551.1 - 5.3e-08 32.3 0.9 1.1e-07 31.3 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ00551.1 - 0.0014 18.2 0.4 0.0029 17.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 OAJ00551.1 - 0.033 13.8 0.1 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Ribosomal_S8e PF01201.17 OAJ00554.1 - 6.9e-49 165.3 2.0 8.7e-49 165.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SPO22 PF08631.5 OAJ00555.1 - 2.8e-05 23.3 0.3 2.8e-05 23.3 0.2 2.7 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.1 OAJ00555.1 - 0.051 14.0 6.1 2.5 8.7 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MULE PF10551.4 OAJ00556.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ00556.1 - 0.003 16.9 0.3 0.0067 15.8 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Macoilin PF09726.4 OAJ00556.1 - 1.2 7.2 8.3 1.6 6.8 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 OAJ00556.1 - 1.4 8.9 7.9 2.8 7.9 5.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MCM_bind PF09739.4 OAJ00557.1 - 3e-16 59.0 0.0 8.1e-08 31.8 0.0 2.3 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 OAJ00557.1 - 1.5e-14 54.0 0.0 3.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Putative alanine racemase DUF3614 PF12267.3 OAJ00558.1 - 0.025 14.8 3.3 0.14 12.3 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Methyltransf_16 PF10294.4 OAJ00559.1 - 1.2e-14 54.1 0.0 3.2e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase RVT_1 PF00078.22 OAJ00560.1 - 7.9e-33 113.6 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CART PF06373.6 OAJ00560.1 - 0.048 13.6 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Pro_isomerase PF00160.16 OAJ00561.1 - 1.4e-37 129.3 0.0 3.2e-37 128.1 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PNP_UDP_1 PF01048.15 OAJ00562.1 - 8.5e-24 83.8 0.0 1.1e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SBDS_C PF09377.5 OAJ00563.1 - 1.3e-43 147.6 0.6 2.1e-43 146.9 0.4 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 OAJ00563.1 - 1.2e-30 105.1 1.6 1.7e-30 104.6 0.5 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MoaE PF02391.12 OAJ00563.1 - 0.081 12.7 0.1 8.1 6.2 0.0 2.4 1 1 1 2 2 2 0 MoaE protein TCTP PF00838.12 OAJ00564.1 - 4.7e-65 218.5 0.7 5.3e-65 218.4 0.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Csm1 PF12539.3 OAJ00565.1 - 3.4e-06 27.4 0.0 1.3e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF972 PF06156.8 OAJ00565.1 - 0.24 11.7 12.6 2.8 8.3 1.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) YlqD PF11068.3 OAJ00565.1 - 0.33 10.9 14.2 1.9 8.5 4.6 2.3 2 0 0 2 2 2 0 YlqD protein DUF812 PF05667.6 OAJ00565.1 - 0.73 8.2 25.2 0.34 9.3 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Ax_dynein_light PF10211.4 OAJ00565.1 - 1.2 8.9 20.7 0.76 9.5 5.3 2.5 2 1 0 2 2 2 0 Axonemal dynein light chain GAS PF13851.1 OAJ00565.1 - 2 7.5 24.3 0.44 9.7 8.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 OAJ00565.1 - 2.7 8.0 10.3 2.6 8.1 2.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ATG16 PF08614.6 OAJ00565.1 - 3.4 7.4 26.0 0.38 10.5 3.6 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CASP_C PF08172.7 OAJ00565.1 - 3.9 6.4 18.9 0.79 8.6 7.9 2.6 1 1 1 2 2 2 0 CASP C terminal HAUS6_N PF14661.1 OAJ00565.1 - 5.7 6.2 23.5 2.8 7.2 4.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Tropomyosin PF00261.15 OAJ00565.1 - 5.9 5.9 32.2 0.49 9.4 3.6 3.1 2 1 1 3 3 3 0 Tropomyosin DUF3138 PF11336.3 OAJ00565.1 - 8.2 4.4 7.3 4.3 5.4 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Nop52 PF05997.7 OAJ00566.1 - 1.1e-53 181.8 0.0 2.6e-52 177.4 0.0 2.1 1 1 0 1 1 1 1 Nucleolar protein,Nop52 HMG_box PF00505.14 OAJ00567.1 - 2.8e-18 65.9 12.3 2.4e-10 40.5 1.5 3.4 3 2 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ00567.1 - 8.5e-13 48.4 10.1 3.5e-08 33.6 1.8 3.3 3 1 0 3 3 3 2 HMG-box domain Imm35 PF15581.1 OAJ00567.1 - 0.16 12.0 0.3 0.84 9.6 0.1 2.2 2 0 0 2 2 2 0 Immunity protein 35 Mucin PF01456.12 OAJ00567.1 - 3.2 7.5 29.3 0.55 9.9 17.3 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein TSSC4 PF15264.1 OAJ00567.1 - 4.2 7.8 13.5 0.57 10.6 3.5 3.2 3 1 0 3 3 3 0 Tumour suppressing sub-chromosomal transferable candidate 4 Pneumo_att_G PF05539.6 OAJ00567.1 - 5.5 6.2 14.6 9 5.5 10.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G BPL_LplA_LipB PF03099.14 OAJ00568.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family cNMP_binding PF00027.24 OAJ00569.1 - 5.3e-14 51.8 0.0 9.4e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sulfate_transp PF00916.15 OAJ00569.1 - 6.9e-13 48.2 0.4 1.2e-12 47.4 0.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 OAJ00569.1 - 6.7e-11 41.6 0.0 1.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 STAS domain DUF1985 PF09331.6 OAJ00569.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) TM_helix PF05552.7 OAJ00569.1 - 0.87 9.2 5.2 0.18 11.4 0.5 2.3 2 0 0 2 2 2 0 Conserved TM helix Sulfate_transp PF00916.15 OAJ00570.1 - 9.3e-21 74.0 2.4 1.7e-20 73.2 1.7 1.4 1 0 0 1 1 1 1 Sulfate transporter family DUF1478 PF07349.6 OAJ00574.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) DAO PF01266.19 OAJ00575.1 - 3.7e-10 39.2 0.4 1.3e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ00575.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ00575.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ00575.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pep_M12B_propep PF01562.14 OAJ00577.1 - 0.033 13.9 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Reprolysin family propeptide DUF1764 PF08576.5 OAJ00580.1 - 7.2 7.4 6.9 4.6 8.0 0.2 2.3 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) MOZART1 PF12554.3 OAJ00582.1 - 1.4e-16 59.6 0.1 1.6e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated UPF0181 PF03701.9 OAJ00582.1 - 0.027 13.7 0.1 0.045 13.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) Abhydrolase_5 PF12695.2 OAJ00583.1 - 1e-15 57.7 0.2 1.6e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ00583.1 - 1e-10 41.8 1.0 1.8e-10 41.0 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ00583.1 - 1.7e-07 31.0 0.4 3.3e-07 30.0 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ00583.1 - 0.0033 16.6 0.1 0.01 15.0 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 OAJ00583.1 - 0.0037 16.8 0.0 0.029 13.9 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ00583.1 - 0.077 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 OAJ00583.1 - 0.096 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Menin PF05053.8 OAJ00584.1 - 1.1 7.3 3.5 1.3 7.0 2.4 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 OAJ00584.1 - 9.1 5.5 20.0 0.89 8.8 10.1 1.7 1 1 1 2 2 2 0 Vta1 like RVT_1 PF00078.22 OAJ00585.1 - 3e-17 62.7 0.0 5.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00585.1 - 1.9e-12 47.3 0.0 4.4e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ00585.1 - 7.4e-05 23.1 0.0 0.0003 21.2 0.0 2.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00585.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ00585.1 - 0.031 14.3 0.2 0.097 12.7 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein gag-asp_proteas PF13975.1 OAJ00585.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Zn_Tnp_IS1 PF03811.8 OAJ00585.1 - 0.29 10.6 0.7 0.72 9.3 0.5 1.6 1 0 0 1 1 1 0 InsA N-terminal domain Syja_N PF02383.13 OAJ00586.1 - 2e-72 243.6 0.0 4.4e-72 242.5 0.0 1.6 1 1 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 OAJ00586.1 - 7.1e-28 96.3 0.0 4.8e-27 93.6 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase Ribul_P_3_epim PF00834.14 OAJ00587.1 - 1.7e-67 226.4 0.0 2.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 OAJ00587.1 - 0.0052 16.3 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain PG_binding_3 PF09374.5 OAJ00587.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain 4F5 PF04419.9 OAJ00588.1 - 8.4e-10 39.2 9.8 8.4e-10 39.2 6.8 2.3 2 0 0 2 2 2 1 4F5 protein family DUF4266 PF14086.1 OAJ00588.1 - 0.14 12.7 2.3 0.14 12.7 0.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4266) Phage_B PF02304.10 OAJ00588.1 - 0.14 12.4 5.0 0.16 12.2 3.4 1.1 1 0 0 1 1 1 0 Scaffold protein B DUF4510 PF14971.1 OAJ00588.1 - 0.19 11.8 4.5 0.23 11.6 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF21 PF01595.15 OAJ00591.1 - 5.4e-36 123.6 1.0 8.6e-36 122.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ00591.1 - 1.2e-08 34.6 1.0 0.0045 16.7 0.0 3.1 4 0 0 4 4 4 2 CBS domain DUF1765 PF08578.5 OAJ00593.1 - 4.5e-29 101.0 1.4 7.1e-29 100.4 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SRP19 PF01922.12 OAJ00595.1 - 0.99 10.0 4.4 5.9 7.5 0.5 3.2 3 0 0 3 3 3 0 SRP19 protein UDP-g_GGTase PF06427.6 OAJ00596.1 - 6.4e-53 179.1 0.0 1.1e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 OAJ00596.1 - 1.8e-06 27.4 0.1 3.5e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Exo_endo_phos PF03372.18 OAJ00597.1 - 0.0002 21.3 0.0 0.0002 21.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Adeno_VII PF03228.9 OAJ00597.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII TIP49 PF06068.8 OAJ00599.1 - 1.6e-175 583.6 0.0 2.4e-175 583.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ00599.1 - 1.5e-10 41.4 0.1 3.7e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ00599.1 - 2e-09 36.8 1.1 1.5e-05 24.1 0.0 3.3 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ00599.1 - 4.9e-07 29.9 0.2 0.054 13.6 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ00599.1 - 3.6e-05 23.5 0.2 0.013 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ00599.1 - 4.1e-05 23.6 0.0 0.0019 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 OAJ00599.1 - 7.7e-05 22.3 0.0 0.0003 20.4 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 OAJ00599.1 - 0.00018 21.5 0.1 0.00037 20.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ00599.1 - 0.00022 20.6 0.1 0.00054 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 OAJ00599.1 - 0.0032 16.6 0.1 0.22 10.6 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ00599.1 - 0.0035 16.7 0.1 0.011 15.1 0.1 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ00599.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ00599.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 OAJ00599.1 - 0.017 15.0 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ00599.1 - 0.017 14.5 0.0 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 OAJ00599.1 - 0.033 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 OAJ00599.1 - 0.056 12.5 0.4 0.12 11.4 0.3 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 OAJ00599.1 - 0.063 12.9 0.1 0.16 11.5 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 OAJ00599.1 - 0.064 14.0 0.0 0.18 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.10 OAJ00599.1 - 0.067 12.0 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain F-box-like PF12937.2 OAJ00600.1 - 0.00023 20.8 0.1 0.00052 19.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like WES_acyltransf PF03007.11 OAJ00601.1 - 8.2e-18 64.8 0.0 1.8e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain CENP-R PF06729.7 OAJ00601.1 - 0.076 12.6 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R Erythro-docking PF09277.6 OAJ00603.1 - 0.013 15.1 0.0 7.8 6.2 0.0 3.5 3 0 0 3 3 3 0 Erythronolide synthase, docking UPF0449 PF15136.1 OAJ00603.1 - 0.049 13.8 0.6 1.6 8.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Adipokin_hormo PF06377.6 OAJ00603.1 - 0.13 12.3 2.0 23 5.2 0.0 3.1 3 0 0 3 3 3 0 Adipokinetic hormone GATase_5 PF13507.1 OAJ00604.1 - 1.5e-95 319.0 0.0 2.4e-95 318.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 OAJ00604.1 - 2.8e-46 157.2 1.9 1.1e-24 87.2 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ00604.1 - 6e-21 74.4 0.0 1.9e-20 72.8 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Nucleos_tra2_C PF07662.8 OAJ00605.1 - 1.1e-67 227.5 1.5 1.1e-67 227.5 1.1 1.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 OAJ00605.1 - 1.1e-13 51.3 4.5 1.1e-13 51.3 3.1 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus FUN14 PF04930.10 OAJ00608.1 - 6.1e-21 74.5 0.9 1.8e-20 73.0 0.1 1.9 2 0 0 2 2 2 1 FUN14 family p450 PF00067.17 OAJ00609.1 - 1.5e-72 244.6 0.0 1.9e-72 244.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MOZ_SAS PF01853.13 OAJ00611.1 - 1.4e-81 272.2 0.1 2.2e-81 271.6 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 OAJ00611.1 - 4.9e-19 67.7 0.0 1.6e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain CDC27 PF09507.5 OAJ00611.1 - 0.0073 15.5 21.1 0.018 14.2 14.6 1.6 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.21 OAJ00611.1 - 0.18 12.2 2.6 0.4 11.1 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type F-protein PF00469.15 OAJ00611.1 - 0.49 9.7 3.4 1.2 8.4 2.3 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Rtf2 PF04641.7 OAJ00611.1 - 4.7 6.3 10.2 23 4.0 7.2 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger RNA_pol_3_Rpc31 PF11705.3 OAJ00611.1 - 6.6 6.6 19.7 0.067 13.1 5.2 2.9 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Phosphoesterase PF04185.9 OAJ00612.1 - 2.6e-78 263.8 0.1 3.6e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_2 PF07731.9 OAJ00613.1 - 4.7e-33 113.6 8.6 8.1e-33 112.8 2.7 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 OAJ00613.1 - 3.2e-30 105.1 0.0 1.7e-29 102.8 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 OAJ00613.1 - 2.5e-27 94.9 5.3 8.8e-19 67.3 0.2 3.6 4 0 0 4 4 4 2 Multicopper oxidase SF3b1 PF08920.5 OAJ00614.1 - 4.4e-26 91.6 5.1 4.4e-26 91.6 3.5 3.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 OAJ00614.1 - 6e-16 58.4 5.7 1.1e-05 25.6 0.1 7.3 6 2 3 10 10 10 5 HEAT repeats HEAT_EZ PF13513.1 OAJ00614.1 - 5e-11 42.7 7.4 0.072 13.6 0.0 7.4 6 3 2 8 8 8 3 HEAT-like repeat HEAT PF02985.17 OAJ00614.1 - 2.5e-07 30.1 10.8 0.65 10.2 0.1 9.0 11 0 0 11 11 11 1 HEAT repeat Adaptin_N PF01602.15 OAJ00614.1 - 6e-06 24.8 0.5 0.00064 18.1 0.0 3.0 1 1 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ00614.1 - 2e-05 24.9 0.5 0.92 9.9 0.0 5.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ00614.1 - 0.00022 20.6 0.3 0.54 9.5 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal Dopey_N PF04118.9 OAJ00614.1 - 0.0096 14.7 0.6 0.093 11.4 0.0 2.8 3 0 0 3 3 3 1 Dopey, N-terminal MMS19_N PF14500.1 OAJ00614.1 - 0.069 12.3 0.1 27 3.9 0.0 3.4 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ00614.1 - 0.25 10.0 0.0 78 1.8 0.0 3.8 3 2 0 4 4 4 0 RNAPII transcription regulator C-terminal PIF1 PF05970.9 OAJ00618.1 - 1.1e-20 73.8 0.0 2.5e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00618.1 - 1.4e-10 41.0 0.0 4.5e-09 36.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ00618.1 - 1.2e-08 34.9 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ00618.1 - 1.7e-06 27.6 0.2 1.7e-06 27.6 0.1 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ00618.1 - 0.0062 16.5 1.0 0.019 14.9 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.21 OAJ00618.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ00618.1 - 0.024 14.7 0.0 0.067 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 OAJ00618.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.6 OAJ00618.1 - 0.19 11.5 0.0 0.58 10.0 0.0 1.7 1 0 0 1 1 1 0 Torsin Apolipoprotein PF01442.13 OAJ00619.1 - 0.0012 18.4 1.5 0.0016 17.9 1.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.1 OAJ00619.1 - 0.016 15.3 1.0 0.016 15.3 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) PRT_C PF08372.5 OAJ00619.1 - 0.056 12.9 0.2 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Fzo_mitofusin PF04799.8 OAJ00619.1 - 0.19 11.0 1.6 0.38 10.1 1.0 1.5 1 1 0 1 1 1 0 fzo-like conserved region Baculo_PEP_C PF04513.7 OAJ00619.1 - 0.51 10.1 2.6 3.4 7.5 1.8 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cyclin_N PF00134.18 OAJ00620.1 - 3.2e-21 75.2 0.0 2.6e-19 69.0 0.0 2.3 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ00620.1 - 1.7e-12 47.3 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain MSA-2c PF12238.3 OAJ00626.1 - 3.3 7.3 13.4 0.25 10.9 1.3 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c AMP-binding PF00501.23 OAJ00634.1 - 2.1e-99 332.7 0.1 2.5e-99 332.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ00634.1 - 1.9e-21 76.7 1.8 6.2e-21 75.1 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 OAJ00635.1 - 5.9e-57 191.5 0.2 6.9e-57 191.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ00635.1 - 1.9e-18 67.0 0.0 2.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ00635.1 - 2.9e-08 33.1 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ00635.1 - 9.6e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ00635.1 - 0.0062 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ00635.1 - 0.04 13.2 0.0 0.098 11.9 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_25 PF13481.1 OAJ00635.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 OAJ00638.1 - 0.22 10.5 2.7 0.35 9.8 1.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Selenoprotein_S PF06936.6 OAJ00639.1 - 0.043 13.3 0.1 0.082 12.4 0.1 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) LSM14 PF12701.2 OAJ00640.1 - 1e-27 95.7 0.0 2.3e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 OAJ00640.1 - 9.8e-10 38.9 0.2 1.5e-08 35.1 0.0 2.7 2 2 0 2 2 2 1 FDF domain SM-ATX PF14438.1 OAJ00640.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain TFIIA PF03153.8 OAJ00640.1 - 0.41 10.5 24.8 0.59 9.9 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC37_N PF03234.9 OAJ00641.1 - 6.3e-39 134.1 5.0 6.3e-39 134.1 3.5 2.8 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 OAJ00641.1 - 7.9e-18 64.5 7.1 6.9e-16 58.2 0.0 2.9 3 0 0 3 3 3 2 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 OAJ00641.1 - 1.3e-16 60.2 0.2 1.3e-16 60.2 0.1 2.4 3 0 0 3 3 3 1 Cdc37 C terminal domain Peptidase_S30 PF01577.11 OAJ00641.1 - 0.56 9.5 5.0 0.1 11.9 0.8 1.6 2 0 0 2 2 2 0 Potyvirus P1 protease GOLGA2L5 PF15070.1 OAJ00642.1 - 0.026 13.0 1.2 0.082 11.3 0.1 1.9 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 PEP-utilisers_N PF05524.8 OAJ00642.1 - 0.052 13.3 1.1 0.11 12.2 0.7 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Glutaredoxin PF00462.19 OAJ00644.1 - 8.6e-19 67.2 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.15 OAJ00644.1 - 4e-15 55.3 0.0 6.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ00644.1 - 0.00036 20.5 0.1 0.049 13.7 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin-like HyaE PF07449.6 OAJ00644.1 - 0.0044 16.9 0.1 0.24 11.3 0.0 3.2 2 2 1 4 4 4 2 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 OAJ00644.1 - 0.0095 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ArsC PF03960.10 OAJ00644.1 - 0.049 13.7 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 ArsC family TrbC_Ftype PF09673.5 OAJ00644.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein HMG_box PF00505.14 OAJ00645.1 - 3.1e-10 40.1 2.7 6.5e-10 39.1 1.8 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 OAJ00645.1 - 0.001 18.4 0.2 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 UCH PF00443.24 OAJ00646.1 - 1.6e-22 79.8 0.0 1.9e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ00646.1 - 3.6e-06 26.6 0.0 4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.9 OAJ00646.1 - 0.075 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS UCH PF00443.24 OAJ00647.1 - 1.2e-44 152.5 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 OAJ00647.1 - 1.5e-12 47.7 0.0 3.5e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 OAJ00647.1 - 1e-08 34.9 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SnoaL PF07366.7 OAJ00649.1 - 0.082 12.4 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Med11 PF10280.4 OAJ00650.1 - 7.9e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 1 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 OAJ00650.1 - 0.068 13.2 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 29 CobT PF06213.7 OAJ00651.1 - 0.0051 15.9 30.1 0.0067 15.5 20.8 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 OAJ00651.1 - 0.14 9.7 6.2 0.14 9.8 4.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 OAJ00651.1 - 0.16 11.2 11.2 0.18 11.0 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 OAJ00651.1 - 0.18 11.1 31.8 0.24 10.7 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 OAJ00651.1 - 0.19 9.5 42.6 0.22 9.4 29.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ00651.1 - 0.34 10.5 27.9 0.52 9.9 19.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BTV_NS2 PF04514.7 OAJ00651.1 - 0.64 8.8 20.0 0.76 8.5 13.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 OAJ00651.1 - 0.64 8.9 4.6 0.66 8.9 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Na_trans_assoc PF06512.8 OAJ00651.1 - 0.66 9.8 18.5 0.69 9.8 12.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Paf1 PF03985.8 OAJ00651.1 - 0.79 8.3 34.1 0.95 8.1 23.6 1.1 1 0 0 1 1 1 0 Paf1 Daxx PF03344.10 OAJ00651.1 - 1.2 7.4 41.3 2 6.8 28.7 1.3 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 OAJ00651.1 - 1.3 8.8 17.1 1.7 8.5 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 OAJ00651.1 - 1.4 8.5 4.7 2.3 7.9 3.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 OAJ00651.1 - 2.4 5.7 17.3 2.7 5.5 12.0 1.0 1 0 0 1 1 1 0 Ycf1 TFIIF_alpha PF05793.7 OAJ00651.1 - 3.2 6.0 37.5 5 5.3 26.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FLO_LFY PF01698.11 OAJ00651.1 - 3.6 6.3 10.4 4.3 6.0 7.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Host_attach PF10116.4 OAJ00651.1 - 6.2 7.0 14.8 9.5 6.4 10.3 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells Trypan_PARP PF05887.6 OAJ00651.1 - 7.5 6.3 28.5 4.9 6.9 18.6 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DPBB_1 PF03330.13 OAJ00652.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.8 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 OAJ00653.1 - 3.4e-71 239.4 0.0 4.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00653.1 - 8.6e-30 103.6 0.0 1e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00653.1 - 4.1e-06 25.9 0.0 5.6e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ00653.1 - 0.009 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ00653.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 OAJ00653.1 - 0.034 13.8 0.1 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyco_hydro_92 PF07971.7 OAJ00657.1 - 4.6e-104 348.8 0.0 6.6e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Rhodanese PF00581.15 OAJ00658.1 - 3.8e-12 46.5 0.0 9.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain LAG1-DNAbind PF09271.6 OAJ00660.1 - 9.9e-24 84.3 0.0 2.9e-19 69.9 0.0 2.7 2 0 0 2 2 2 2 LAG1, DNA binding BTD PF09270.5 OAJ00660.1 - 5.7e-17 61.9 0.0 1.6e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain p450 PF00067.17 OAJ00661.1 - 1.7e-50 171.8 0.0 3.6e-50 170.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MAPEG PF01124.13 OAJ00662.1 - 4.9e-24 84.3 1.3 6.2e-24 84.0 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Hpre_diP_synt_I PF07456.6 OAJ00662.1 - 0.022 14.5 0.2 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase component I WD40 PF00400.27 OAJ00663.1 - 2.5e-53 176.1 13.3 1.4e-09 37.4 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ00663.1 - 0.00057 18.1 0.6 3.5 5.6 0.1 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAJ00663.1 - 0.0064 15.9 0.3 0.75 9.2 0.2 2.9 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 OAJ00663.1 - 0.071 11.8 0.1 1.3 7.6 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Seipin PF06775.9 OAJ00664.1 - 2.8e-39 134.6 0.0 8.7e-26 90.6 0.0 2.2 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) Cwf_Cwc_15 PF04889.7 OAJ00664.1 - 0.6 9.7 21.5 0.63 9.7 7.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein OB_NTP_bind PF07717.11 OAJ00666.1 - 2.2e-23 82.2 0.0 4.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ00666.1 - 8.5e-23 80.3 0.0 1.7e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ00666.1 - 2e-15 56.4 0.0 3.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ00666.1 - 5.1e-05 23.4 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 OAJ00666.1 - 7.6e-05 22.2 0.0 0.00019 20.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 OAJ00666.1 - 0.0023 17.8 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ00666.1 - 0.17 11.5 0.0 0.48 10.0 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase tRNA-synt_His PF13393.1 OAJ00667.1 - 1e-37 129.8 0.1 2.1e-33 115.7 0.0 2.5 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 OAJ00667.1 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ00667.1 - 1.7e-07 31.1 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 OAJ00667.1 - 4.6e-07 29.4 0.7 4.6e-07 29.4 0.5 2.2 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_2 PF00152.15 OAJ00667.1 - 2.3e-05 23.3 0.0 0.012 14.4 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Pkinase PF00069.20 OAJ00668.1 - 7.6e-36 123.5 0.0 9.8e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00668.1 - 3.1e-12 46.1 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_16 PF10294.4 OAJ00669.1 - 1.4e-10 40.9 0.0 2.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 OAJ00669.1 - 0.025 13.9 0.2 0.12 11.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ00669.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HTH_Tnp_Tc5 PF03221.11 OAJ00674.1 - 3e-08 33.3 0.0 6.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Cation_efflux PF01545.16 OAJ00675.1 - 1.5e-09 37.3 0.4 2.6e-09 36.5 0.3 1.4 1 0 0 1 1 1 1 Cation efflux family TFIIF_alpha PF05793.7 OAJ00676.1 - 0.0016 16.8 9.2 0.002 16.6 6.4 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mucin PF01456.12 OAJ00676.1 - 0.079 12.7 9.0 0.1 12.3 6.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Glycophorin_A PF01102.13 OAJ00676.1 - 0.51 10.1 3.7 0.87 9.3 2.6 1.4 1 0 0 1 1 1 0 Glycophorin A SpoIIIAH PF12685.2 OAJ00676.1 - 0.57 9.6 6.1 0.72 9.3 4.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein EBV-NA3 PF05009.7 OAJ00676.1 - 0.95 8.6 3.9 0.43 9.7 0.3 1.9 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Atrophin-1 PF03154.10 OAJ00676.1 - 1.3 7.0 10.8 1.6 6.8 7.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family MULE PF10551.4 OAJ00677.1 - 3.5e-17 62.3 0.0 6.6e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ00677.1 - 0.02 13.4 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family zf-CCHC_4 PF14392.1 OAJ00677.1 - 0.97 9.1 6.3 4.4 7.0 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle TFIIF_alpha PF05793.7 OAJ00679.1 - 0.044 12.1 17.4 0.061 11.6 12.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) IncA PF04156.9 OAJ00680.1 - 2.6e-05 23.9 5.9 3.8e-05 23.3 4.1 1.2 1 0 0 1 1 1 1 IncA protein GrpE PF01025.14 OAJ00680.1 - 7.4e-05 22.3 2.4 0.0001 21.8 1.7 1.2 1 0 0 1 1 1 1 GrpE Baculo_PEP_C PF04513.7 OAJ00680.1 - 0.0011 18.7 5.6 0.39 10.5 0.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.4 OAJ00680.1 - 0.011 15.5 6.3 0.24 11.2 4.3 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AATF-Che1 PF13339.1 OAJ00680.1 - 0.03 14.4 2.7 0.053 13.6 1.9 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF3584 PF12128.3 OAJ00680.1 - 0.03 11.6 3.8 0.038 11.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.10 OAJ00680.1 - 0.034 13.3 2.1 0.045 12.9 1.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.6 OAJ00680.1 - 0.037 12.6 1.2 0.051 12.2 0.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Lectin_N PF03954.9 OAJ00680.1 - 0.047 13.0 6.7 0.024 14.0 1.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF1409 PF07197.7 OAJ00680.1 - 0.054 13.5 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF4164 PF13747.1 OAJ00680.1 - 0.055 13.6 5.1 0.14 12.3 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) HAUS-augmin3 PF14932.1 OAJ00680.1 - 0.087 11.9 4.1 0.12 11.5 2.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1664 PF07889.7 OAJ00680.1 - 0.11 12.2 5.2 0.38 10.5 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TraC PF07820.7 OAJ00680.1 - 0.18 11.9 0.8 0.27 11.4 0.1 1.6 2 0 0 2 2 1 0 TraC-like protein Syntaxin-6_N PF09177.6 OAJ00680.1 - 0.31 11.4 2.9 7.9 6.9 0.1 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.6 OAJ00680.1 - 0.72 9.7 4.5 3.7 7.4 3.4 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Hsk3 PF08227.6 OAJ00680.1 - 1.2 9.3 6.1 0.42 10.8 0.2 2.8 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like H-kinase_dim PF02895.9 OAJ00680.1 - 2.4 8.5 5.5 1.6 9.1 0.3 2.7 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SlyX PF04102.7 OAJ00680.1 - 6.3 7.2 9.4 16 5.9 3.7 3.0 1 1 1 2 2 2 0 SlyX Fe-S_biosyn PF01521.15 OAJ00682.1 - 5.9e-11 42.2 0.0 9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Peptidase_M16_C PF05193.16 OAJ00683.1 - 1.6e-13 50.7 0.1 2.3e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF982 PF06169.7 OAJ00684.1 - 0.063 13.0 1.4 0.083 12.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Pga1 PF10333.4 OAJ00684.1 - 0.11 12.1 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator PIF1 PF05970.9 OAJ00685.1 - 2.3e-23 82.7 0.0 1.7e-21 76.5 0.0 2.2 1 1 1 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00685.1 - 4.1e-14 52.6 0.5 1.5e-12 47.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ00685.1 - 7e-10 38.9 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ00685.1 - 2.2e-07 30.5 0.7 5.6e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ00685.1 - 0.0016 18.4 0.0 0.0066 16.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ00685.1 - 0.019 15.0 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.6 OAJ00685.1 - 0.04 13.8 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Torsin ResIII PF04851.10 OAJ00685.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 OAJ00685.1 - 0.19 11.1 0.0 0.47 9.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol_delta_4 PF04081.8 OAJ00687.1 - 4.5e-19 68.9 0.1 6.6e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF1180 PF06679.7 OAJ00687.1 - 0.8 9.5 2.6 1.5 8.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) ATP-synt_C PF00137.16 OAJ00688.1 - 2.7e-29 100.8 34.8 7.8e-18 64.1 9.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C MFS_1 PF07690.11 OAJ00693.1 - 1.1e-21 76.9 8.9 1.5e-21 76.5 6.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00693.1 - 6.5e-06 24.9 1.5 9.4e-06 24.4 1.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 OAJ00693.1 - 0.0094 14.3 0.9 0.014 13.8 0.7 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein PROCN PF08083.6 OAJ00694.1 - 1.4e-207 689.0 5.0 2.1e-207 688.4 3.5 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 OAJ00694.1 - 2.1e-126 419.9 0.7 3.4e-126 419.2 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 OAJ00694.1 - 9e-93 307.9 0.3 4.1e-62 208.2 0.0 2.8 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 OAJ00694.1 - 6.6e-78 259.6 2.4 6.6e-78 259.6 1.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 OAJ00694.1 - 3.1e-61 204.9 0.0 5.9e-61 204.0 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 OAJ00694.1 - 1.9e-42 145.4 0.0 2.5e-25 89.5 0.0 2.6 1 1 1 2 2 2 2 Hom_end-associated Hint RRM_4 PF10598.4 OAJ00694.1 - 1.7e-41 139.9 0.0 3.8e-41 138.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 OAJ00694.1 - 6.1e-36 122.8 0.0 1.5e-35 121.6 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain Hom_end PF05204.9 OAJ00694.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 Homing endonuclease JAB PF01398.16 OAJ00694.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hint_2 PF13403.1 OAJ00694.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Hint domain PagP PF07017.6 OAJ00695.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP rOmpB PF12334.3 OAJ00695.1 - 0.069 12.5 0.3 0.095 12.0 0.2 1.1 1 0 0 1 1 1 0 Rickettsia outer membrane protein B LSM PF01423.17 OAJ00696.1 - 3.1e-16 58.6 0.1 3.7e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF2370 PF10176.4 OAJ00697.1 - 6.8e-70 235.0 0.0 4.5e-69 232.3 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 OAJ00697.1 - 0.03 14.5 3.3 0.075 13.2 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) BAF1_ABF1 PF04684.8 OAJ00697.1 - 0.23 10.2 0.4 0.4 9.4 0.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dus PF01207.12 OAJ00698.1 - 4e-62 209.8 0.0 6.6e-61 205.8 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_11 PF13414.1 OAJ00698.1 - 5e-10 38.8 3.9 0.0009 18.8 1.1 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ00698.1 - 0.001 18.5 8.1 0.52 10.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ00698.1 - 0.031 14.1 2.6 1.1 9.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ00698.1 - 0.33 11.6 4.5 7.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ00698.1 - 0.92 10.3 6.3 2.4 9.0 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ00698.1 - 1.2 9.5 3.9 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S9 PF00326.16 OAJ00700.1 - 6.1e-30 104.0 0.0 2.1e-29 102.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAJ00700.1 - 4.8e-10 39.6 0.2 1.1e-09 38.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ00700.1 - 6e-09 35.7 0.0 1.7e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAJ00700.1 - 0.012 14.1 0.0 0.02 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 OAJ00700.1 - 0.017 14.4 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 OAJ00700.1 - 0.022 14.3 0.1 0.13 11.7 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ00700.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PPR_2 PF13041.1 OAJ00701.1 - 0.00025 20.9 0.0 0.017 15.0 0.0 2.8 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 OAJ00701.1 - 0.0024 18.0 3.4 1 9.8 0.1 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain ZZ PF00569.12 OAJ00702.1 - 2.4e-22 78.1 64.5 1e-08 34.5 3.3 5.4 5 0 0 5 5 5 4 Zinc finger, ZZ type Lig_chan-Glu_bd PF10613.4 OAJ00702.1 - 0.24 11.4 0.0 0.57 10.2 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site zf-met PF12874.2 OAJ00702.1 - 1.3 9.3 9.9 30 4.9 2.2 4.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Aldedh PF00171.17 OAJ00703.1 - 3.2e-11 42.2 0.0 7.2e-11 41.0 0.0 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Pkinase PF00069.20 OAJ00704.1 - 2.8e-23 82.3 0.0 5.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00704.1 - 1.5e-13 50.4 0.0 5.2e-13 48.6 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ00704.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Fringe PF02434.11 OAJ00705.1 - 1e-08 34.7 0.6 4.1e-08 32.7 0.4 1.9 1 1 0 1 1 1 1 Fringe-like WW PF00397.21 OAJ00706.1 - 3.5e-06 26.7 5.6 9.3e-06 25.4 3.9 1.8 1 0 0 1 1 1 1 WW domain QRPTase_C PF01729.14 OAJ00707.1 - 3.6e-45 153.5 0.3 5e-45 153.0 0.2 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 OAJ00707.1 - 6.5e-21 73.9 0.0 2e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain LysR_substrate PF03466.15 OAJ00707.1 - 0.095 11.7 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 LysR substrate binding domain SPA PF08616.5 OAJ00708.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.4 OAJ00708.1 - 0.28 9.6 0.0 7.6 4.8 0.0 2.1 2 0 0 2 2 2 0 Transport protein Avl9 BAF1_ABF1 PF04684.8 OAJ00708.1 - 2.4 6.8 5.6 4.5 5.9 3.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dynamitin PF04912.9 OAJ00711.1 - 1.2e-24 86.8 1.1 3.4e-13 49.1 0.0 3.3 3 1 0 3 3 3 3 Dynamitin zf-RING_2 PF13639.1 OAJ00712.1 - 9.9e-14 50.8 3.8 2.3e-13 49.7 2.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ00712.1 - 1.9e-13 50.3 0.8 3.4e-13 49.4 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ00712.1 - 9.3e-07 28.6 0.9 1.8e-06 27.6 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ00712.1 - 9.6e-07 28.3 3.1 2.1e-06 27.2 2.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ00712.1 - 6.3e-06 25.8 2.6 1.1e-05 25.0 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ00712.1 - 7.4e-06 25.5 4.6 3.2e-05 23.4 3.3 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ00712.1 - 1.3e-05 25.0 3.3 1.3e-05 25.0 2.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ00712.1 - 0.00011 21.8 2.7 0.00028 20.5 1.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 OAJ00712.1 - 0.0045 16.8 3.1 0.008 16.0 1.6 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 OAJ00712.1 - 0.039 13.9 0.4 0.088 12.7 0.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 OAJ00712.1 - 1.8 8.1 4.0 1.2 8.8 1.4 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PWWP PF00855.12 OAJ00713.1 - 0.0001 22.3 0.2 0.00021 21.4 0.2 1.5 1 0 0 1 1 1 1 PWWP domain Snf7 PF03357.16 OAJ00714.1 - 1.1e-43 148.6 16.0 1.1e-43 148.6 11.1 2.0 1 1 1 2 2 2 1 Snf7 Misat_Tub_SegII PF10644.4 OAJ00714.1 - 0.022 14.8 0.4 0.056 13.4 0.3 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3508 PF12018.3 OAJ00714.1 - 0.031 13.2 5.7 0.22 10.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Ribosomal_60s PF00428.14 OAJ00714.1 - 0.23 11.8 10.2 0.095 13.1 3.4 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein CCP_MauG PF03150.9 OAJ00714.1 - 0.27 11.5 2.0 0.8 9.9 0.7 2.0 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase TMCO5 PF14992.1 OAJ00714.1 - 0.81 8.7 8.6 1.4 7.9 5.8 1.5 1 1 0 1 1 1 0 TMCO5 family AAA_13 PF13166.1 OAJ00714.1 - 2.8 6.3 9.4 8.8 4.6 6.6 1.5 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 OAJ00714.1 - 2.9 6.7 10.3 2.3 7.0 6.3 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3138 PF11336.3 OAJ00714.1 - 3.2 5.8 10.3 1.2 7.2 0.8 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) NUDIX PF00293.23 OAJ00715.1 - 1.5e-18 66.7 0.2 3.7e-18 65.4 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain Ctr PF04145.10 OAJ00716.1 - 1.3e-36 125.7 0.3 2.6e-36 124.8 0.2 1.5 1 0 0 1 1 1 1 Ctr copper transporter family Sm_multidrug_ex PF06695.6 OAJ00716.1 - 0.26 11.4 1.8 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative small multi-drug export protein SURF1 PF02104.10 OAJ00717.1 - 2.8e-42 144.9 0.0 9.3e-42 143.2 0.0 1.8 2 1 0 2 2 2 1 SURF1 family GLTSCR1 PF15249.1 OAJ00719.1 - 8.6e-12 45.1 0.1 2.2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region RRS1 PF04939.7 OAJ00720.1 - 1.3e-52 177.6 1.2 1.5e-52 177.3 0.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Aminotran_1_2 PF00155.16 OAJ00721.1 - 7e-90 301.5 0.0 8e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 OAJ00722.1 - 4.6e-70 236.3 0.0 5.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ00722.1 - 4.3e-06 25.7 0.0 6.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 OAJ00722.1 - 1.2e-05 23.8 0.0 3.1e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 OAJ00722.1 - 0.019 14.0 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 OAJ00722.1 - 0.087 11.8 0.1 0.21 10.5 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family UCH PF00443.24 OAJ00723.1 - 2.5e-48 164.5 0.0 5.4e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ00723.1 - 7.4e-22 78.1 0.0 7.4e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 OAJ00723.1 - 3.3e-20 71.3 0.2 7.1e-09 35.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 OAJ00723.1 - 4e-20 71.6 14.8 1.9e-18 66.3 1.1 3.6 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein Complex1_51K PF01512.12 OAJ00724.1 - 3.3e-48 163.2 0.0 5.6e-48 162.5 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 OAJ00724.1 - 1e-20 72.5 0.4 2.2e-20 71.5 0.3 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 OAJ00724.1 - 2.5e-06 27.2 0.0 5.8e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 SLBB domain WD40 PF00400.27 OAJ00725.1 - 1.8e-54 179.7 17.9 1.6e-08 34.1 0.0 9.4 8 1 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 OAJ00725.1 - 2.4e-06 27.0 0.1 6e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 OAJ00725.1 - 0.00026 19.2 1.2 0.051 11.7 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 OAJ00725.1 - 0.019 14.4 0.0 8.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 OAJ00725.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Radical_SAM PF04055.16 OAJ00726.1 - 1.7e-13 51.0 0.1 2.6e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily DUF1335 PF07056.6 OAJ00726.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) dUTPase PF00692.14 OAJ00727.1 - 7.8e-32 109.4 0.1 6.3e-21 74.1 0.0 2.1 1 1 1 2 2 2 2 dUTPase Ribosomal_S7 PF00177.16 OAJ00728.1 - 7.5e-39 132.6 0.8 9.2e-39 132.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_C14 PF00656.17 OAJ00729.1 - 4e-64 216.6 0.0 4.9e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain DXP_synthase_N PF13292.1 OAJ00729.1 - 0.13 11.1 0.1 0.25 10.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_S24 PF00717.18 OAJ00730.1 - 2.3e-08 33.5 0.1 4.9e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase S24-like Retrotrans_gag PF03732.12 OAJ00734.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1900 PF08954.6 OAJ00735.1 - 7.9e-47 158.1 0.0 1e-45 154.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 OAJ00735.1 - 1.6e-31 107.7 0.3 3.1e-31 106.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 OAJ00735.1 - 1e-14 53.7 4.1 3.2e-05 23.6 0.1 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat RNA_pol_Rpb8 PF03870.10 OAJ00736.1 - 7.3e-38 129.8 0.4 3.9e-36 124.2 0.3 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb8 polyprenyl_synt PF00348.12 OAJ00737.1 - 3.5e-45 153.9 0.0 2e-22 79.2 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase DUF2296 PF10058.4 OAJ00738.1 - 9.3e-17 60.5 0.0 1.7e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Mu-like_Com PF10122.4 OAJ00738.1 - 0.016 14.2 0.2 0.082 11.9 0.1 2.0 1 1 1 2 2 2 0 Mu-like prophage protein Com MacB_PCD PF12704.2 OAJ00738.1 - 0.6 9.6 3.9 5.8 6.4 0.5 2.2 2 0 0 2 2 2 0 MacB-like periplasmic core domain zf-tcix PF14952.1 OAJ00738.1 - 0.87 8.9 3.7 0.25 10.7 0.3 1.8 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding UQ_con PF00179.21 OAJ00740.1 - 8.7e-53 177.5 0.0 9.8e-53 177.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ00740.1 - 0.00012 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ00740.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 OAJ00740.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Oxidored_FMN PF00724.15 OAJ00741.1 - 1e-48 166.0 0.0 1.1e-37 129.8 0.0 3.1 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 OAJ00741.1 - 0.0028 16.5 0.3 0.24 10.1 0.1 2.3 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) SNARE_assoc PF09335.6 OAJ00742.1 - 3.8e-23 82.0 1.0 3.2e-22 79.0 0.6 2.6 2 1 0 2 2 2 1 SNARE associated Golgi protein Dimer_Tnp_hAT PF05699.9 OAJ00746.1 - 1.2e-10 40.8 0.0 3.8e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_1 PF00078.22 OAJ00747.1 - 3.2e-19 69.1 0.0 6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ00747.1 - 0.00045 20.6 0.0 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00747.1 - 0.0093 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease PRKCSH PF07915.8 OAJ00752.1 - 1.1e-12 48.5 0.0 6.5e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein Atu4866 PF11512.3 OAJ00753.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 DUF2762 PF10960.3 OAJ00754.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) MBF1 PF08523.5 OAJ00757.1 - 6.3e-13 48.5 0.7 1.4e-12 47.3 0.5 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 OAJ00757.1 - 8.5e-12 44.7 0.4 1.5e-11 43.9 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 OAJ00757.1 - 4.6e-06 26.5 0.1 6.6e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 OAJ00757.1 - 0.00025 21.1 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HpcH_HpaI PF03328.9 OAJ00757.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family SNF5 PF04855.7 OAJ00758.1 - 7.1e-52 176.3 1.3 7.2e-51 172.9 0.9 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PGI PF00342.14 OAJ00759.1 - 3.4e-209 695.2 0.0 3.9e-209 695.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase RRM_1 PF00076.17 OAJ00760.1 - 1.4e-15 56.6 0.2 2.8e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ00760.1 - 1.4e-13 50.5 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ00760.1 - 3.5e-08 33.1 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF508 PF04370.7 OAJ00760.1 - 1.9 8.0 5.5 3.3 7.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) F1F0-ATPsyn_F PF10791.4 OAJ00761.1 - 3e-32 110.7 0.1 3.7e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Herpes_BLLF1 PF05109.8 OAJ00761.1 - 0.26 9.1 3.2 0.28 9.0 2.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Hexapep PF00132.19 OAJ00762.1 - 2.6e-11 42.5 9.6 3.8e-05 22.9 0.6 4.7 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ00762.1 - 6.7e-07 28.7 9.0 0.33 10.5 0.0 4.4 4 1 0 4 4 4 4 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 OAJ00762.1 - 0.094 11.2 0.2 0.18 10.3 0.0 1.5 2 0 0 2 2 2 0 L-fucokinase PAPS_reduct PF01507.14 OAJ00763.1 - 7.7e-35 120.2 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family VPS28 PF03997.7 OAJ00764.1 - 6e-45 153.1 0.0 7.6e-44 149.5 0.0 2.3 1 1 0 1 1 1 1 VPS28 protein Pex14_N PF04695.8 OAJ00764.1 - 0.15 12.0 0.9 0.27 11.2 0.4 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myb_DNA-bind_3 PF12776.2 OAJ00765.1 - 0.025 15.1 0.1 0.025 15.1 0.1 2.9 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Methyltransf_18 PF12847.2 OAJ00765.1 - 0.29 11.7 0.0 0.29 11.7 0.0 2.6 4 0 0 4 4 4 0 Methyltransferase domain DUF3357 PF11837.3 OAJ00765.1 - 5.3 6.9 11.9 14 5.6 2.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TFIIA PF03153.8 OAJ00765.1 - 6.3 6.5 43.4 6.2 6.6 0.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Polysacc_synt_4 PF04669.8 OAJ00767.1 - 4.4e-25 88.1 5.5 2.6e-24 85.6 3.8 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Gluconate_2-dh3 PF13618.1 OAJ00767.1 - 0.016 15.3 0.1 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 SLT PF01464.15 OAJ00769.1 - 0.00034 20.0 0.0 0.002 17.6 0.0 2.1 2 1 0 2 2 2 1 Transglycosylase SLT domain Pkinase PF00069.20 OAJ00770.1 - 7.6e-40 136.6 0.0 1.9e-26 92.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00770.1 - 5.7e-22 78.0 0.0 8.2e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sigma70_ner PF04546.8 OAJ00770.1 - 0.2 11.2 1.9 1.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Prp19 PF08606.6 OAJ00771.1 - 1.9e-28 97.9 1.7 3.8e-28 97.0 1.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 OAJ00771.1 - 4.6e-16 57.9 0.2 2.6e-07 30.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Rtf2 PF04641.7 OAJ00771.1 - 0.0026 16.9 0.1 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ00771.1 - 0.0046 16.4 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 OAJ00771.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain DUF3450 PF11932.3 OAJ00771.1 - 0.026 13.8 1.6 0.055 12.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.3 OAJ00771.1 - 0.072 12.8 0.9 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DAGK_cat PF00781.19 OAJ00771.1 - 0.11 11.9 0.4 0.33 10.3 0.3 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RibD_C PF01872.12 OAJ00772.1 - 1.3e-33 116.3 0.0 2.4e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 RibD C-terminal domain Sec7 PF01369.15 OAJ00772.1 - 3.2e-29 101.9 0.0 4.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IBN_N PF03810.14 OAJ00777.1 - 3.2e-07 30.1 0.0 2.2e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 OAJ00777.1 - 0.031 12.5 0.1 0.11 10.7 0.0 1.9 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Orn_Arg_deC_N PF02784.11 OAJ00778.1 - 7.1e-69 231.7 0.0 1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ00778.1 - 3.3e-27 94.5 0.0 6.2e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KH_3 PF13014.1 OAJ00778.1 - 0.056 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 KH domain B12-binding PF02310.14 OAJ00778.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain zf-C2H2_jaz PF12171.3 OAJ00779.1 - 2.1e-09 37.2 3.1 3.7e-09 36.4 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ00779.1 - 2.4e-06 27.5 1.9 3.8e-06 26.8 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ00779.1 - 0.00049 20.1 0.2 0.00069 19.6 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 OAJ00779.1 - 0.0097 15.6 2.0 0.014 15.2 1.4 1.4 1 1 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 OAJ00779.1 - 0.051 13.9 2.9 0.051 13.9 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type SGT1 PF07093.6 OAJ00782.1 - 6.2e-45 153.6 73.4 1.4e-36 126.1 50.9 4.1 1 1 0 1 1 1 1 SGT1 protein Flavin_Reduct PF01613.13 OAJ00783.1 - 1.9e-29 102.5 0.3 2.6e-29 102.0 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.17 OAJ00784.1 - 4.1e-43 146.8 0.0 5.1e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ00784.1 - 3.3e-12 45.8 0.0 7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ00784.1 - 0.00017 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAJ00784.1 - 0.00032 20.6 0.0 0.00096 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ00784.1 - 0.0029 18.4 0.0 0.0062 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain HSP70 PF00012.15 OAJ00786.1 - 4.9e-68 229.5 2.4 1e-40 139.2 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 OAJ00786.1 - 0.00015 20.4 0.0 0.00079 18.1 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Actin PF00022.14 OAJ00786.1 - 0.00065 18.2 0.3 0.13 10.6 0.0 2.1 1 1 1 2 2 2 2 Actin PilM_2 PF11104.3 OAJ00786.1 - 0.029 13.2 0.0 0.11 11.3 0.0 1.8 1 1 0 1 1 1 0 Type IV pilus assembly protein PilM; Ribosomal_S11 PF00411.14 OAJ00787.1 - 7.1e-38 129.1 0.6 8.8e-38 128.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L38e PF01781.13 OAJ00788.1 - 3.5e-31 106.7 0.4 4.4e-31 106.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.4 OAJ00788.1 - 0.096 12.1 0.2 0.31 10.5 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) MBOAT PF03062.14 OAJ00790.1 - 1.4e-48 165.6 21.4 1.4e-48 165.6 14.8 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family RVT_1 PF00078.22 OAJ00791.1 - 5.2e-18 65.1 0.0 9.5e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00791.1 - 5.3e-12 45.8 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ00791.1 - 0.0001 22.7 0.1 0.00033 21.0 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00791.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ00791.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DDE_Tnp_4 PF13359.1 OAJ00792.1 - 1.3e-22 80.0 0.0 3.2e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF4219 PF13961.1 OAJ00794.1 - 1.1e-07 31.1 0.1 2.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 OAJ00794.1 - 0.00037 20.0 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ00794.1 - 0.0031 17.2 0.6 0.0049 16.6 0.1 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAJ00794.1 - 0.0065 16.0 0.2 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Pax2_C PF12403.3 OAJ00794.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Paired-box protein 2 C terminal DUF2077 PF09850.4 OAJ00794.1 - 1.5 8.1 6.3 2.6 7.3 2.7 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) rve PF00665.21 OAJ00801.1 - 8.4e-18 64.6 0.0 2e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ00801.1 - 1.3e-15 57.3 0.0 2.9e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 OAJ00801.1 - 0.00039 19.8 0.0 0.0033 16.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAJ00801.1 - 0.0019 18.0 1.9 0.0019 18.0 1.3 2.0 2 0 0 2 2 2 1 Zinc knuckle Nitro_FeMo-Co PF02579.12 OAJ00801.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor zf-CCHC_4 PF14392.1 OAJ00801.1 - 0.23 11.1 1.7 0.77 9.4 1.2 1.9 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 OAJ00802.1 - 4.1e-36 124.3 0.0 2.1e-17 63.2 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00802.1 - 5.5e-25 87.8 0.0 2.6e-13 50.1 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.1 OAJ00802.1 - 4.7e-11 43.0 1.4 9.5e-06 26.0 0.1 3.3 3 0 0 3 3 2 2 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00802.1 - 4.7e-06 26.3 0.7 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ00802.1 - 9.1e-05 22.3 0.0 0.43 10.5 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease Lectin_N PF03954.9 OAJ00802.1 - 0.0035 16.7 0.6 0.7 9.2 0.1 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Retrotrans_gag PF03732.12 OAJ00802.1 - 0.024 14.6 0.3 8.4 6.5 0.1 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein Reo_sigmaC PF04582.7 OAJ00802.1 - 0.06 12.5 2.6 0.042 13.0 0.3 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ00802.1 - 0.47 10.2 1.7 10 5.9 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-Q PF13094.1 OAJ00802.1 - 0.59 10.1 0.1 1.8 8.6 0.1 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NVEALA PF14055.1 OAJ00802.1 - 1.7 8.4 1.4 35 4.1 0.0 2.8 3 0 0 3 3 3 0 NVEALA protein MscS_porin PF12795.2 OAJ00802.1 - 1.7 7.8 7.7 0.26 10.5 0.8 2.6 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain ADIP PF11559.3 OAJ00802.1 - 1.8 8.4 0.2 3.5 7.5 0.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TBPIP PF07106.8 OAJ00802.1 - 2.3 7.7 0.1 4.3 6.8 0.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 OAJ00802.1 - 2.7 7.5 1.3 7.9 6.0 0.2 2.0 2 0 0 2 2 2 0 IncA protein Cast PF10174.4 OAJ00802.1 - 2.8 5.8 0.0 4.4 5.2 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 OAJ00802.1 - 3.2 6.3 0.3 5.3 5.6 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ALIX_LYPXL_bnd PF13949.1 OAJ00802.1 - 7.1 5.4 1.2 14 4.5 0.8 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Filament PF00038.16 OAJ00802.1 - 9.5 5.5 0.4 1.4e+02 1.7 0.0 2.0 2 0 0 2 2 2 0 Intermediate filament protein Hydantoinase_B PF02538.9 OAJ00806.1 - 1.2e-183 611.1 0.0 6.6e-182 605.4 0.0 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase COPI_C PF06957.6 OAJ00809.1 - 0.58 8.6 18.2 0.41 9.1 4.3 3.3 3 0 0 3 3 3 0 Coatomer (COPI) alpha subunit C-terminus Serglycin PF04360.7 OAJ00810.1 - 0.016 14.9 0.1 0.016 14.9 0.1 1.8 2 0 0 2 2 2 0 Serglycin Cellulase PF00150.13 OAJ00811.1 - 5.5e-15 55.3 0.0 4.2e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 OAJ00816.1 - 0.0014 18.2 0.1 0.0034 17.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like SgrR_N PF12793.2 OAJ00816.1 - 0.027 14.4 0.2 0.075 13.0 0.1 1.7 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term F-box PF00646.28 OAJ00816.1 - 0.089 12.4 0.5 7.9 6.2 0.1 2.8 2 0 0 2 2 2 0 F-box domain PMT_2 PF13231.1 OAJ00817.1 - 1.5 8.7 7.0 0.64 9.9 1.1 2.3 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Pro-kuma_activ PF09286.6 OAJ00818.1 - 3.4e-42 143.8 1.7 7.4e-20 71.4 0.1 2.5 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ00818.1 - 8.7e-17 61.1 25.2 2.7e-12 46.4 4.4 3.4 2 2 2 4 4 4 2 Subtilase family DUF2617 PF10936.3 OAJ00818.1 - 0.0042 16.6 0.5 2.5 7.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function DUF2617 Surf_Ag_VNR PF07244.10 OAJ00818.1 - 0.0061 16.9 0.2 36 4.8 0.0 4.2 4 0 0 4 4 4 2 Surface antigen variable number repeat GCR1_C PF12550.3 OAJ00820.1 - 4.1e-21 74.6 1.7 7.4e-21 73.8 1.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DAO PF01266.19 OAJ00822.1 - 3.7e-18 65.5 1.1 9.7e-09 34.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ00822.1 - 0.001 18.0 0.0 0.0021 17.0 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ00822.1 - 0.0019 18.1 1.1 0.0039 17.1 0.4 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAJ00822.1 - 0.0022 17.1 0.2 0.0042 16.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 OAJ00822.1 - 0.0046 16.3 0.1 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 OAJ00822.1 - 0.017 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 OAJ00822.1 - 0.022 14.1 1.1 0.046 13.0 0.8 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 OAJ00822.1 - 0.038 13.8 0.1 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ00822.1 - 0.043 14.2 1.6 0.083 13.2 1.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ00822.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 OAJ00822.1 - 0.091 12.4 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_deac_1 PF01522.16 OAJ00824.1 - 4.9e-23 81.0 0.0 8.8e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pol_alpha_B_N PF08418.5 OAJ00824.1 - 0.34 10.4 5.9 0.53 9.7 4.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Linker_histone PF00538.14 OAJ00825.1 - 2.7e-10 40.1 0.2 5.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family CIAPIN1 PF05093.8 OAJ00826.1 - 5.3e-30 103.4 4.9 1.4e-29 102.1 3.4 1.7 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Cu_amine_oxid PF01179.15 OAJ00827.1 - 2.2e-156 520.7 0.0 2.7e-156 520.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 OAJ00827.1 - 3.5e-14 52.6 0.0 8.8e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 OAJ00827.1 - 0.00049 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Glyco_hydro_65m PF03632.10 OAJ00828.1 - 2.8e-87 292.7 0.1 1.1e-86 290.9 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 OAJ00828.1 - 4.2e-19 68.8 0.0 7.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF2152 PF10222.4 OAJ00828.1 - 0.00065 18.0 0.0 0.32 9.1 0.0 3.3 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65C PF03633.10 OAJ00828.1 - 0.0093 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Gln-synt_N PF03951.14 OAJ00828.1 - 0.17 11.5 0.5 1.6 8.3 0.0 2.8 4 0 0 4 4 4 0 Glutamine synthetase, beta-Grasp domain p450 PF00067.17 OAJ00829.1 - 2.1e-71 240.8 0.0 3e-70 237.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Porin_3 PF01459.17 OAJ00830.1 - 9.4e-61 205.5 0.5 1e-60 205.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rrp15p PF07890.7 OAJ00831.1 - 1.6e-27 96.1 0.4 1.6e-27 96.1 0.3 2.7 2 2 0 2 2 2 1 Rrp15p Daxx PF03344.10 OAJ00831.1 - 0.0015 17.0 16.0 0.0021 16.6 11.1 1.1 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 OAJ00831.1 - 0.015 13.7 21.7 0.024 13.0 15.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med17 PF10156.4 OAJ00831.1 - 1.9 6.7 9.7 1.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Merozoite_SPAM PF07133.6 OAJ00831.1 - 2.3 8.0 25.6 5 6.9 17.7 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 OAJ00831.1 - 3.1 5.7 20.5 0.56 8.1 10.8 1.8 2 0 0 2 2 2 0 CDC45-like protein BUD22 PF09073.5 OAJ00831.1 - 4.6 6.1 31.8 0.33 9.9 16.5 2.1 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.7 OAJ00831.1 - 4.9 4.9 31.5 0.072 11.0 15.4 2.2 2 1 0 2 2 2 0 Nop14-like family UCH PF00443.24 OAJ00832.1 - 4.6e-14 52.1 0.0 7.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ00832.1 - 2.2e-07 30.6 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1631 PF07793.6 OAJ00832.1 - 0.71 7.9 2.6 1 7.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) adh_short PF00106.20 OAJ00833.1 - 3.3e-07 30.3 0.4 7.7e-07 29.1 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ00833.1 - 4.7e-06 26.5 0.0 6.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 OAJ00833.1 - 0.0014 19.0 0.6 0.018 15.4 0.2 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 OAJ00833.1 - 0.0034 17.0 0.2 0.0049 16.5 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 OAJ00833.1 - 0.0041 16.8 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ00833.1 - 0.084 12.8 0.7 0.21 11.5 0.3 1.7 1 1 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 OAJ00833.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DEAD PF00270.24 OAJ00834.1 - 3.3e-48 163.3 0.0 1.7e-46 157.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ00834.1 - 5.3e-27 93.4 0.0 1.8e-26 91.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ00834.1 - 2.5e-05 24.2 0.0 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ00834.1 - 9.5e-05 21.3 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 OAJ00834.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 OAJ00834.1 - 0.16 10.3 0.0 1.3 7.3 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) CTP_transf_2 PF01467.21 OAJ00839.1 - 2.3e-29 102.4 0.0 3.3e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Amastin PF07344.6 OAJ00840.1 - 0.71 9.4 13.0 0.025 14.1 4.0 2.1 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF159 PF02586.9 OAJ00841.1 - 2e-47 161.4 0.0 2.5e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Sas10_Utp3 PF04000.10 OAJ00842.1 - 4e-10 39.7 0.2 7.4e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RRN3 PF05327.6 OAJ00842.1 - 0.071 11.2 1.1 0.098 10.7 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2146 PF10220.4 OAJ00842.1 - 0.93 7.3 5.6 1.3 6.8 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF4611 PF15387.1 OAJ00842.1 - 7 6.8 13.4 0.58 10.3 4.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Transferase PF02458.10 OAJ00843.1 - 3e-06 25.9 0.0 1.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Transferase family LNS2 PF08235.8 OAJ00844.1 - 3.9e-67 224.7 0.0 6e-54 181.8 0.0 2.4 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 OAJ00844.1 - 1.5e-28 98.7 0.1 7.3e-19 67.4 0.0 2.4 2 0 0 2 2 2 2 lipin, N-terminal conserved region AF1Q PF15017.1 OAJ00844.1 - 0.0019 18.0 0.4 0.0019 18.0 0.3 2.4 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Acid_phosphat_B PF03767.9 OAJ00844.1 - 0.029 13.7 0.0 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Aldedh PF00171.17 OAJ00845.1 - 6.6e-73 245.6 0.0 8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lyase_1 PF00206.15 OAJ00846.1 - 1.7e-92 309.9 0.0 2.6e-92 309.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 OAJ00846.1 - 1.8e-28 98.4 0.0 3.8e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Peptidase_M24 PF00557.19 OAJ00847.1 - 1.1e-42 146.0 0.1 1.5e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 OAJ00847.1 - 8.5e-07 29.5 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Nol1_Nop2_Fmu PF01189.12 OAJ00848.1 - 2.5e-14 53.3 0.0 5.1e-09 35.9 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family RRM_6 PF14259.1 OAJ00849.1 - 2.3e-08 33.8 0.0 0.0035 17.2 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ00849.1 - 4e-08 32.7 0.1 0.012 15.1 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1824 PF08854.5 OAJ00849.1 - 0.072 12.7 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Nup35_RRM PF05172.8 OAJ00850.1 - 2.4e-06 27.2 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 OAJ00850.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RtcB PF01139.12 OAJ00851.1 - 9.1e-85 285.1 0.0 5.8e-84 282.5 0.0 2.1 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB PCI PF01399.22 OAJ00852.1 - 5.4e-10 39.5 0.2 1.8e-09 37.8 0.1 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.8 OAJ00852.1 - 0.013 14.9 3.5 0.88 9.0 0.0 3.9 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF882) GILT PF03227.11 OAJ00854.1 - 1.9e-07 30.8 0.0 4.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) ClpB_D2-small PF10431.4 OAJ00855.1 - 0.0082 16.0 0.1 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Apolipoprotein PF01442.13 OAJ00856.1 - 0.0049 16.3 1.5 0.01 15.3 1.0 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Perilipin PF03036.11 OAJ00856.1 - 0.0059 15.4 1.9 0.07 11.9 0.0 2.5 1 1 0 2 2 2 1 Perilipin family MRP-S27 PF10037.4 OAJ00856.1 - 0.024 13.5 0.3 0.036 13.0 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2408 PF10303.4 OAJ00856.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF883 PF05957.8 OAJ00856.1 - 0.24 11.8 4.9 0.44 10.9 1.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) MFS_1 PF07690.11 OAJ00857.1 - 1.3e-16 60.2 39.2 1.3e-16 60.2 27.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily CRT-like PF08627.5 OAJ00857.1 - 0.014 15.3 2.0 0.96 9.3 0.1 3.2 3 0 0 3 3 3 0 CRT-like DUF454 PF04304.8 OAJ00857.1 - 0.13 12.2 0.0 0.13 12.2 0.0 5.4 4 1 0 4 4 4 0 Protein of unknown function (DUF454) Sugar_tr PF00083.19 OAJ00857.1 - 0.32 9.5 34.2 0.0093 14.5 11.5 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter rve PF00665.21 OAJ00861.1 - 3.8e-15 56.0 0.0 8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Rad60-SLD PF11976.3 OAJ00861.1 - 2.9e-07 30.0 0.0 0.0028 17.3 0.0 4.8 5 0 0 5 5 5 1 Ubiquitin-2 like Rad60 SUMO-like RVT_1 PF00078.22 OAJ00861.1 - 2.1e-06 27.2 0.0 4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ00861.1 - 1.4e-05 25.5 0.1 4.1e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.5 OAJ00861.1 - 0.0084 15.6 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ00861.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Aldo_ket_red PF00248.16 OAJ00862.1 - 6.1e-71 238.5 0.0 6.8e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Chs3p PF12271.3 OAJ00864.1 - 3e-115 384.2 16.7 3.5e-115 384.0 11.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Methyltransf_16 PF10294.4 OAJ00865.1 - 4.8e-43 146.6 0.0 8.2e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ00865.1 - 9.2e-05 22.9 0.1 0.0002 21.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ00865.1 - 0.0023 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Med15 PF09606.5 OAJ00866.1 - 0.34 9.0 63.8 0.4 8.8 44.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dicty_REP PF05086.7 OAJ00866.1 - 1.1 6.9 2.2 1.4 6.6 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zn_clus PF00172.13 OAJ00868.1 - 2.7e-08 33.5 10.2 4.8e-08 32.7 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 OAJ00869.1 - 5.5e-30 104.9 0.0 1e-29 104.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ00869.1 - 1.2e-15 57.7 0.1 2e-15 56.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ00869.1 - 2.1e-10 40.5 0.0 9.4e-10 38.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family CMD PF02627.15 OAJ00869.1 - 7.3e-07 28.9 1.9 9.1e-07 28.6 0.0 2.1 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Ndr PF03096.9 OAJ00869.1 - 2e-06 26.5 0.0 8.1e-06 24.5 0.0 1.8 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 OAJ00869.1 - 0.049 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 OAJ00869.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 OAJ00869.1 - 0.092 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Dioxygenase_C PF00775.16 OAJ00870.1 - 1.1e-07 31.3 0.2 5.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase HIT PF01230.18 OAJ00871.1 - 2.9e-14 53.3 0.0 5.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ00871.1 - 4.6e-07 30.0 0.0 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF3446 PF11928.3 OAJ00871.1 - 0.63 10.2 13.0 0.35 11.1 4.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Ribosomal_L22 PF00237.14 OAJ00872.1 - 7e-20 70.9 0.6 1.3e-19 70.0 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3317 PF11779.3 OAJ00873.1 - 0.00011 21.5 0.2 0.00015 21.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Neurensin PF14927.1 OAJ00873.1 - 0.059 12.7 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Neurensin Myosin_N PF02736.14 OAJ00874.1 - 0.0049 16.5 4.7 0.011 15.4 3.3 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain DUF2945 PF11160.3 OAJ00874.1 - 0.0077 16.0 2.1 0.011 15.5 1.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) Oligomerisation PF02410.10 OAJ00875.1 - 0.0055 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Oligomerisation domain ADH_zinc_N PF00107.21 OAJ00876.1 - 5.8e-29 100.2 0.0 9.3e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ00876.1 - 2.5e-11 44.5 0.0 5.7e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ00876.1 - 3e-09 36.6 0.0 1.6e-08 34.2 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RICTOR_V PF14668.1 OAJ00876.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 SIR2 PF02146.12 OAJ00877.1 - 8e-29 100.6 0.0 3.3e-17 62.7 0.0 2.1 2 0 0 2 2 2 2 Sir2 family TIM21 PF08294.6 OAJ00878.1 - 2.5e-14 53.1 0.1 1.7e-12 47.2 0.0 3.1 2 1 1 3 3 3 1 TIM21 APH PF01636.18 OAJ00879.1 - 5.7e-20 72.0 0.7 5.7e-20 72.0 0.5 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ00879.1 - 0.0028 17.0 0.0 0.29 10.4 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.15 OAJ00879.1 - 0.08 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 OAJ00879.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase vATP-synt_E PF01991.13 OAJ00884.1 - 6.7e-57 191.9 14.7 7.8e-57 191.7 10.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit IncA PF04156.9 OAJ00884.1 - 1.2 8.7 9.7 1.8 8.1 6.7 1.4 1 0 0 1 1 1 0 IncA protein Cornichon PF03311.9 OAJ00886.1 - 9.9e-53 177.6 11.3 1.1e-52 177.4 7.8 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 OAJ00886.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 OAJ00886.1 - 0.34 10.4 9.5 1 8.8 6.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) CS PF04969.11 OAJ00887.1 - 1.1e-05 25.8 0.1 2.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 OAJ00887.1 - 0.35 11.2 15.1 0.53 10.6 10.5 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Glypican PF01153.14 OAJ00887.1 - 2.5 6.6 6.2 2 6.8 3.1 1.6 2 0 0 2 2 2 0 Glypican LRR_6 PF13516.1 OAJ00888.1 - 9.8e-13 46.7 13.0 0.22 11.6 0.1 7.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 OAJ00888.1 - 8.9e-07 28.4 14.0 0.083 12.5 1.9 6.2 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ00888.1 - 1.2e-05 24.9 12.1 0.26 11.0 1.0 6.2 4 2 1 6 6 6 2 Leucine rich repeat LRR_1 PF00560.28 OAJ00888.1 - 4.3e-05 22.9 3.0 25 5.4 0.0 6.8 7 1 0 7 7 7 0 Leucine Rich Repeat Rap1_C PF11626.3 OAJ00888.1 - 0.01 15.6 0.1 0.071 13.0 0.1 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain LRR_7 PF13504.1 OAJ00888.1 - 0.022 14.8 8.1 25 5.6 0.0 6.0 5 0 0 5 5 5 0 Leucine rich repeat MYCBPAP PF14646.1 OAJ00888.1 - 0.093 11.4 2.4 0.13 10.9 1.7 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family Prothymosin PF03247.9 OAJ00888.1 - 0.17 12.0 19.6 0.3 11.2 13.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 OAJ00888.1 - 1.1 8.7 15.0 2.1 7.8 10.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 OAJ00888.1 - 1.5 7.4 16.3 1.8 7.1 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 OAJ00888.1 - 1.7 6.4 10.6 2.3 6.0 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 OAJ00888.1 - 1.8 7.2 10.0 2.2 6.8 6.9 1.1 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.8 OAJ00888.1 - 3.9 7.0 11.7 6.9 6.2 8.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 OAJ00888.1 - 7.2 4.9 12.6 9.7 4.5 8.7 1.1 1 0 0 1 1 1 0 Daxx Family FHA PF00498.21 OAJ00889.1 - 5.4e-16 58.4 0.0 9.8e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF3138 PF11336.3 OAJ00889.1 - 8.5 4.4 11.1 1 7.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) MFS_1 PF07690.11 OAJ00890.1 - 8.7e-41 139.7 29.4 8.7e-41 139.7 20.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ00890.1 - 2.6e-12 46.0 5.4 2.6e-12 46.0 3.8 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter GTP_EFTU PF00009.22 OAJ00891.1 - 6.5e-22 77.8 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 OAJ00891.1 - 9.1e-10 38.5 0.8 8.4e-09 35.4 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 OAJ00891.1 - 2.8e-06 27.4 0.5 0.038 14.1 0.0 2.7 1 1 1 2 2 2 2 Elongation factor Tu C-terminal domain PduV-EutP PF10662.4 OAJ00891.1 - 0.0023 17.4 0.0 3.4 7.1 0.0 3.5 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 OAJ00891.1 - 0.0078 16.1 0.0 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 OAJ00891.1 - 0.0095 15.5 1.0 0.046 13.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Sulfotransfer_3 PF13469.1 OAJ00892.1 - 0.00027 21.9 2.2 0.00073 20.4 1.5 1.7 1 1 0 1 1 1 1 Sulfotransferase family XhlA PF10779.4 OAJ00892.1 - 0.055 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Arylsulfotran_2 PF14269.1 OAJ00893.1 - 2.4e-38 132.0 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 OAJ00893.1 - 6.3e-11 41.4 0.0 1.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF556 PF04476.8 OAJ00893.1 - 0.27 10.4 0.0 0.4 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF556) WD40 PF00400.27 OAJ00894.1 - 1.4e-38 129.4 18.6 8.8e-09 34.9 0.7 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ00894.1 - 0.0013 18.3 0.4 0.086 12.5 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) CBS PF00571.23 OAJ00895.1 - 9.1e-16 57.3 8.8 4.3e-06 26.4 0.4 5.5 6 0 0 6 6 6 4 CBS domain Actin PF00022.14 OAJ00896.1 - 2.5e-59 200.6 0.0 5.6e-35 120.5 0.0 2.3 2 0 0 2 2 2 2 Actin P21-Arc PF04062.9 OAJ00897.1 - 9.2e-77 256.7 0.0 1e-76 256.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Pyr_redox_2 PF07992.9 OAJ00898.1 - 3.1e-19 69.6 0.0 5.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ00898.1 - 1.2e-13 51.2 0.2 1.7e-09 37.9 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 OAJ00898.1 - 2.2e-08 32.8 2.6 2.5e-05 23.2 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 OAJ00898.1 - 2.8e-07 30.5 2.5 6.3e-07 29.4 1.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ00898.1 - 3e-07 29.7 0.9 0.00018 21.0 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ00898.1 - 5.2e-06 25.5 1.6 0.00022 20.3 0.5 2.4 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.1 OAJ00898.1 - 6.5e-05 23.0 0.0 0.36 10.8 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 OAJ00898.1 - 0.014 15.6 0.2 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding GAS PF13851.1 OAJ00898.1 - 0.024 13.8 0.8 0.039 13.1 0.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.1 OAJ00898.1 - 0.039 13.5 2.7 1.2 8.8 0.4 2.5 2 0 0 2 2 2 0 EF-hand domain pair TALPID3 PF15324.1 OAJ00898.1 - 0.047 11.0 1.4 0.066 10.5 1.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Rer1 PF03248.8 OAJ00899.1 - 1.3e-77 259.3 0.0 1.7e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Rer1 family DUF4395 PF14340.1 OAJ00899.1 - 0.0024 17.9 2.4 0.37 10.8 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4395) DUF4131 PF13567.1 OAJ00899.1 - 0.092 12.1 5.2 0.68 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) EI24 PF07264.6 OAJ00899.1 - 1.5 8.1 8.8 5.4 6.3 6.1 1.7 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) OPT PF03169.10 OAJ00903.1 - 3.5e-185 617.0 56.1 4.1e-185 616.8 38.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 OAJ00903.1 - 2.7 7.0 4.4 2.5 7.1 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) MtmB PF05369.7 OAJ00908.1 - 0.12 10.5 0.0 0.23 9.5 0.0 1.4 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB WXG100 PF06013.7 OAJ00908.1 - 0.24 11.4 4.9 0.22 11.5 0.5 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Iso_dh PF00180.15 OAJ00909.1 - 4.5e-69 233.0 0.0 5.4e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2638 PF10937.3 OAJ00911.1 - 0.17 12.8 0.2 0.17 12.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Ras PF00071.17 OAJ00912.1 - 6.8e-54 181.6 0.0 7.9e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ00912.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ00912.1 - 2.1e-07 30.3 0.0 3.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ00912.1 - 0.0097 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAJ00912.1 - 0.053 13.0 0.0 1.7 8.0 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribonuclease PF00545.15 OAJ00913.1 - 6.6e-12 45.3 0.5 8.6e-12 44.9 0.4 1.2 1 0 0 1 1 1 1 ribonuclease Peptidase_C25_C PF03785.9 OAJ00914.1 - 0.038 13.7 0.4 0.038 13.7 0.3 1.8 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain C-term_anchor PF13461.1 OAJ00914.1 - 0.15 12.5 0.9 4.2 7.9 0.0 2.6 2 1 1 3 3 3 0 Cell-wall surface anchor repeat Peptidase_M3 PF01432.15 OAJ00915.1 - 8.4e-131 437.1 0.0 1.2e-130 436.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Transposase_21 PF02992.9 OAJ00916.1 - 3.8e-13 49.0 0.1 9.4e-13 47.7 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ00916.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) EF-hand_1 PF00036.27 OAJ00917.1 - 9.7e-19 65.1 0.0 5.8e-06 25.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 OAJ00917.1 - 1.4e-15 55.7 0.1 6.2e-06 25.6 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 OAJ00917.1 - 1.5e-15 55.7 0.0 0.00085 18.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 OAJ00917.1 - 1.3e-12 47.6 0.0 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ00917.1 - 5.7e-10 38.6 0.2 9.2e-06 25.1 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair Toprim_2 PF13155.1 OAJ00917.1 - 0.041 14.2 0.1 1.6 9.1 0.0 2.6 1 1 2 3 3 3 0 Toprim-like Glycos_transf_2 PF00535.21 OAJ00918.1 - 2.5e-20 72.8 0.0 5.3e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ00918.1 - 3.9e-08 33.3 0.5 2.1e-05 24.4 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Mss4 PF04421.8 OAJ00919.1 - 6.2e-10 38.7 0.7 0.0013 18.4 0.2 2.6 2 0 0 2 2 2 2 Mss4 protein Acetyltransf_1 PF00583.19 OAJ00919.1 - 8.2e-05 22.5 0.2 0.00044 20.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ00919.1 - 0.0048 17.0 0.0 0.29 11.3 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ00919.1 - 0.079 12.7 0.1 17 5.2 0.0 2.5 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 OAJ00919.1 - 0.18 11.6 0.5 0.5 10.2 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SHR3_chaperone PF08229.6 OAJ00920.1 - 5e-24 84.3 0.0 9.3e-24 83.4 0.0 1.4 1 1 0 1 1 1 1 ER membrane protein SH3 DUF572 PF04502.8 OAJ00920.1 - 0.066 12.4 1.1 0.073 12.2 0.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SecG PF03840.9 OAJ00920.1 - 0.12 12.1 0.6 0.12 12.1 0.4 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Mito_carr PF00153.22 OAJ00921.1 - 2.1e-54 181.1 1.1 1.2e-17 63.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein PAPA-1 PF04795.7 OAJ00922.1 - 1.2e-13 51.5 10.3 1.2e-13 51.5 7.1 3.7 3 1 0 3 3 3 1 PAPA-1-like conserved region Daxx PF03344.10 OAJ00922.1 - 0.6 8.5 51.6 1.1 7.6 7.0 2.1 2 0 0 2 2 2 0 Daxx Family Apt1 PF10351.4 OAJ00922.1 - 6.4 5.5 15.4 1.5e+02 1.0 10.6 2.5 1 1 0 1 1 1 0 Golgi-body localisation protein domain EPSP_synthase PF00275.15 OAJ00923.1 - 1.4e-109 366.3 0.0 2.1e-109 365.7 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 OAJ00923.1 - 4.3e-96 320.8 0.0 1.3e-95 319.2 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 OAJ00923.1 - 6.6e-49 166.5 0.0 1.1e-48 165.8 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 OAJ00923.1 - 8.9e-25 86.5 0.0 4.4e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 OAJ00923.1 - 3.8e-22 78.8 0.0 4.2e-21 75.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_DH PF01488.15 OAJ00923.1 - 1.1e-10 41.7 0.0 2.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 OAJ00923.1 - 9.4e-07 28.3 0.3 4e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Acetyltransf_1 PF00583.19 OAJ00924.1 - 4e-10 39.6 0.1 9.6e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.5 OAJ00924.1 - 0.00012 21.7 0.2 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.1 OAJ00924.1 - 0.00018 21.5 0.0 0.89 9.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ00924.1 - 0.0026 17.8 0.0 0.9 9.6 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ00924.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3438 PF11920.3 OAJ00924.1 - 0.13 11.0 1.2 0.2 10.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF4349 PF14257.1 OAJ00924.1 - 0.28 10.3 6.5 0.053 12.7 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Ribosomal_L13e PF01294.13 OAJ00925.1 - 1.9e-59 200.1 7.7 2.4e-59 199.8 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e DUF374 PF04028.8 OAJ00925.1 - 0.11 11.7 0.1 0.25 10.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) HTH_OrfB_IS605 PF12323.3 OAJ00926.1 - 4.9e-09 35.3 0.4 9.7e-09 34.4 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Malate_DH PF12434.3 OAJ00926.1 - 0.11 12.1 1.8 0.25 11.0 1.2 1.5 1 0 0 1 1 1 0 Malate dehydrogenase enzyme HMGL-like PF00682.14 OAJ00931.1 - 1.1e-61 208.4 0.0 1.6e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 OAJ00931.1 - 5.8e-18 64.9 0.1 4.1e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain His_Phos_1 PF00300.17 OAJ00932.1 - 0.084 12.9 0.1 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Sterol_MT_C PF08498.5 OAJ00935.1 - 1.3e-27 95.4 0.3 2e-27 94.9 0.2 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 OAJ00935.1 - 1.1e-17 64.0 0.0 1.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ00935.1 - 2.9e-17 62.9 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ00935.1 - 1.1e-15 57.7 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ00935.1 - 3.8e-14 53.2 0.0 1.9e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 OAJ00935.1 - 2.1e-13 49.9 0.0 3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 OAJ00935.1 - 7.4e-13 48.7 0.0 1.6e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ00935.1 - 1.5e-12 47.8 0.0 4.4e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ00935.1 - 2.6e-11 43.5 0.0 7.7e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 OAJ00935.1 - 2.1e-06 27.3 0.1 3.4e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 OAJ00935.1 - 7.6e-06 25.4 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 OAJ00935.1 - 2.5e-05 23.9 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 OAJ00935.1 - 6.5e-05 22.0 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAJ00935.1 - 0.00017 22.3 0.0 0.00043 21.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 OAJ00935.1 - 0.00084 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase PrmA PF06325.8 OAJ00935.1 - 0.00085 18.5 0.0 0.0038 16.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 OAJ00935.1 - 0.0035 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MetW PF07021.7 OAJ00935.1 - 0.0049 16.2 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 OAJ00935.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HRM PF02793.17 OAJ00935.1 - 0.0087 16.0 0.3 0.021 14.8 0.2 1.6 1 0 0 1 1 1 1 Hormone receptor domain Methyltransf_4 PF02390.12 OAJ00935.1 - 0.025 13.6 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 OAJ00935.1 - 0.077 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 OAJ00935.1 - 0.091 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.13 OAJ00935.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PsbM PF05151.7 OAJ00938.1 - 0.25 10.9 2.2 0.73 9.4 1.5 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) WD40 PF00400.27 OAJ00939.1 - 5.4e-19 67.3 9.3 2.8e-06 26.9 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ00939.1 - 0.12 10.6 0.0 0.27 9.4 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain UPF0542 PF15086.1 OAJ00941.1 - 0.0029 17.2 1.1 3 7.6 0.0 3.0 3 0 0 3 3 3 2 Uncharacterised protein family UPF0542 Med30 PF11315.3 OAJ00941.1 - 0.005 16.9 3.4 0.2 11.7 2.3 2.3 2 0 0 2 2 2 1 Mediator complex subunit 30 DUF4065 PF13274.1 OAJ00941.1 - 0.14 12.9 0.7 0.98 10.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) SIR2 PF02146.12 OAJ00942.1 - 6e-54 182.4 0.0 4.2e-53 179.7 0.0 2.0 1 1 0 1 1 1 1 Sir2 family DUF592 PF04574.8 OAJ00942.1 - 2.9e-07 30.1 0.3 6e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) Arf PF00025.16 OAJ00943.1 - 7.5e-56 188.1 0.0 1.2e-54 184.1 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 OAJ00943.1 - 2.6e-06 26.4 0.0 3.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 OAJ00943.1 - 0.00013 21.4 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ00943.1 - 0.00017 22.0 0.0 0.00024 21.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 OAJ00943.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 OAJ00943.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain KOW PF00467.24 OAJ00944.1 - 1.6e-08 33.8 3.3 1.7e-08 33.8 1.1 1.9 2 0 0 2 2 2 1 KOW motif E1-E2_ATPase PF00122.15 OAJ00946.1 - 4.7e-68 228.6 6.8 2.1e-67 226.5 0.3 3.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ00946.1 - 9e-23 81.8 0.6 1.8e-22 80.8 0.4 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ00946.1 - 5.3e-12 46.2 0.0 9.7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ00946.1 - 3.8e-11 42.2 0.0 9.7e-11 40.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ00946.1 - 0.0014 18.3 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ00946.1 - 0.032 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 OAJ00946.1 - 0.04 13.7 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif DUF3628 PF12300.3 OAJ00949.1 - 0.11 12.5 1.4 0.18 11.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Med3 PF11593.3 OAJ00949.1 - 1.6 7.8 5.0 2.2 7.4 3.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cid2 PF09774.4 OAJ00950.1 - 0.11 12.5 0.2 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Caffeine-induced death protein 2 Thymidylat_synt PF00303.14 OAJ00951.1 - 2.5e-111 371.0 0.0 3.3e-111 370.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.17 OAJ00951.1 - 6.8e-29 100.9 0.1 2e-28 99.4 0.1 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Complex1_LYR PF05347.10 OAJ00952.1 - 0.00037 20.2 0.8 0.0015 18.2 0.5 2.1 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Rhodanese PF00581.15 OAJ00952.1 - 0.0056 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Complex1_LYR_1 PF13232.1 OAJ00952.1 - 0.0083 16.3 0.5 0.022 14.9 0.3 1.8 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_23 PF13489.1 OAJ00952.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ00952.1 - 0.16 12.5 0.4 4.1 8.0 0.2 3.0 3 1 0 3 3 3 0 Methyltransferase domain Pkinase PF00069.20 OAJ00953.1 - 9.4e-52 175.7 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00953.1 - 1.2e-46 158.8 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ00953.1 - 0.003 17.3 0.0 0.01 15.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pol_alpha_B_N PF08418.5 OAJ00953.1 - 5.5 6.4 7.9 12 5.3 5.5 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NUP PF06516.6 OAJ00954.1 - 9.8e-114 379.3 0.1 1.1e-113 379.1 0.1 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Acetyltransf_1 PF00583.19 OAJ00956.1 - 2.7e-05 24.0 0.1 4.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 OAJ00956.1 - 0.0047 16.8 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3HC4_2 PF13923.1 OAJ00957.1 - 7.7e-09 35.4 2.9 7.7e-09 35.4 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ00957.1 - 3.1e-08 33.3 2.6 1.8e-07 30.8 0.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ00957.1 - 5.9e-08 32.2 1.7 5.9e-08 32.2 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ00957.1 - 1.7e-05 24.4 3.6 0.00013 21.6 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ00957.1 - 6.3e-05 22.6 1.7 6.3e-05 22.6 1.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ00957.1 - 0.00023 20.9 3.7 0.00023 20.9 2.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ00957.1 - 0.00088 18.9 0.8 0.00088 18.9 0.6 1.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-dskA_traR PF01258.12 OAJ00957.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger zf-Nse PF11789.3 OAJ00957.1 - 0.077 12.5 0.2 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCI_S1-cap PF14674.1 OAJ00959.1 - 0.094 12.7 0.1 0.29 11.2 0.1 1.8 1 0 0 1 1 1 0 FANCI solenoid 1 cap AT_hook PF02178.14 OAJ00961.1 - 0.12 12.0 3.7 0.42 10.4 2.6 2.0 1 0 0 1 1 1 0 AT hook motif AT_hook PF02178.14 OAJ00962.1 - 0.073 12.7 4.3 0.2 11.4 3.0 1.8 1 0 0 1 1 1 0 AT hook motif Cyclin_N PF00134.18 OAJ00963.1 - 1.4e-17 63.4 0.0 3.2e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Helitron_like_N PF14214.1 OAJ00964.1 - 6.7e-09 35.7 0.1 1.4e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus GrpE PF01025.14 OAJ00965.1 - 0.014 14.9 0.8 0.021 14.3 0.6 1.3 1 0 0 1 1 1 0 GrpE Apolipoprotein PF01442.13 OAJ00965.1 - 0.024 14.1 2.0 0.038 13.4 1.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PIF1 PF05970.9 OAJ00966.1 - 1.9e-16 59.9 0.0 5.6e-16 58.4 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ00966.1 - 1.7e-05 24.4 0.6 0.0069 15.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ00971.1 - 1.7e-25 89.7 0.0 3.1e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) POPLD PF08170.7 OAJ00971.1 - 0.047 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 POPLD (NUC188) domain Vps4_C PF09336.5 OAJ00971.1 - 0.071 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF1289 PF06945.8 OAJ00972.1 - 0.035 13.5 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Ribosomal_L23 PF00276.15 OAJ00973.1 - 6.5e-08 32.4 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Pol_alpha_B_N PF08418.5 OAJ00973.1 - 2.1 7.8 4.7 4.4 6.7 3.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal F-box-like PF12937.2 OAJ00974.1 - 0.0031 17.1 1.0 0.0098 15.6 0.3 2.2 1 1 1 2 2 2 1 F-box-like Sua5_yciO_yrdC PF01300.13 OAJ00976.1 - 3.9e-47 159.8 0.0 8.8e-47 158.6 0.0 1.6 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 OAJ00976.1 - 3.9e-24 85.1 0.0 2.7e-23 82.3 0.0 2.3 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Methyltransf_16 PF10294.4 OAJ00977.1 - 5.1e-08 32.5 0.0 7.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ00977.1 - 0.0026 18.3 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ00977.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 OAJ00977.1 - 0.024 14.2 0.0 0.72 9.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ00977.1 - 0.078 13.4 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.15 OAJ00978.1 - 8.3e-62 205.3 0.3 1.7e-27 95.1 0.0 4.1 4 0 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.1 OAJ00978.1 - 1.5e-44 152.0 0.0 1.3e-37 129.4 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ00978.1 - 3.6e-18 65.4 0.4 0.003 17.6 0.0 4.6 4 1 0 4 4 4 4 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ00978.1 - 2.8e-14 53.2 0.8 0.00023 21.3 0.0 5.0 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.12 OAJ00978.1 - 9.1e-13 47.7 0.3 3.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.1 OAJ00978.1 - 9.9e-10 38.3 0.0 0.00011 22.2 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 OAJ00978.1 - 3.3e-07 30.0 1.3 0.01 15.4 0.1 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 OAJ00978.1 - 5.7e-06 25.9 2.1 0.5 9.9 0.0 3.7 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 OAJ00978.1 - 0.00058 19.9 2.5 0.85 9.6 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 OAJ00978.1 - 0.0082 15.9 0.0 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Thioredoxin domain ERp29_N PF07912.8 OAJ00978.1 - 0.036 13.9 0.0 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 ERp29, N-terminal domain Glutaredoxin PF00462.19 OAJ00978.1 - 0.048 13.6 0.2 16 5.5 0.0 3.7 3 1 0 3 3 3 0 Glutaredoxin Ribosomal_L40e PF01020.12 OAJ00978.1 - 0.54 9.9 1.9 20 4.8 0.0 2.8 2 1 1 3 3 3 0 Ribosomal L40e family Pkinase PF00069.20 OAJ00979.1 - 1.2e-05 24.5 0.0 7.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ00979.1 - 0.0063 15.6 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LIM PF00412.17 OAJ00980.1 - 4e-21 74.8 14.8 5.7e-12 45.5 2.8 3.0 2 1 0 2 2 2 2 LIM domain zf-FPG_IleRS PF06827.9 OAJ00980.1 - 3.7 7.2 0.0 3.7 7.2 0.0 4.7 5 0 0 5 5 5 0 Zinc finger found in FPG and IleRS Ldh_1_N PF00056.18 OAJ00981.1 - 2.3e-46 157.1 0.4 3.3e-46 156.5 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ00981.1 - 4.1e-41 140.6 0.0 5.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ00981.1 - 4.7e-06 25.5 0.0 8.1e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 OAJ00981.1 - 0.0035 16.4 0.3 0.059 12.4 0.2 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 OAJ00981.1 - 0.009 15.3 0.1 0.45 9.8 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase Retrotrans_gag PF03732.12 OAJ00982.1 - 1.7e-05 24.8 0.6 3.5e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Sec1 PF00995.18 OAJ00983.1 - 1.8e-146 489.0 0.0 3.4e-146 488.1 0.0 1.4 1 1 0 1 1 1 1 Sec1 family YlbD_coat PF14071.1 OAJ00983.1 - 0.16 12.0 0.5 0.42 10.6 0.4 1.6 1 0 0 1 1 1 0 Putative coat protein F-box-like PF12937.2 OAJ00984.1 - 0.00029 20.4 0.2 0.00082 19.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like RhoGAP PF00620.22 OAJ00985.1 - 2.2e-43 147.4 0.0 4.1e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.19 OAJ00985.1 - 0.00021 21.0 0.0 0.00055 19.7 0.0 1.6 2 0 0 2 2 2 1 PX domain PH PF00169.24 OAJ00985.1 - 0.014 15.5 0.2 0.24 11.6 0.1 2.3 1 1 0 1 1 1 0 PH domain RVT_1 PF00078.22 OAJ00986.1 - 1.5e-18 66.9 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ00986.1 - 1e-14 54.7 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ00986.1 - 1.4e-05 25.5 0.1 6.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ00986.1 - 0.0024 17.6 0.1 0.0093 15.7 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ00986.1 - 0.0032 17.3 0.0 0.008 16.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease TAP42 PF04177.7 OAJ00987.1 - 2.2e-59 201.1 0.0 3.1e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 TAP42-like family Nop PF01798.13 OAJ00987.1 - 0.057 12.7 0.7 0.095 11.9 0.5 1.3 1 0 0 1 1 1 0 Putative snoRNA binding domain Sporozoite_P67 PF05642.6 OAJ00987.1 - 0.21 9.3 5.2 0.046 11.5 1.2 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Bap31 PF05529.7 OAJ00988.1 - 0.015 14.8 1.6 0.027 13.9 0.0 1.8 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like AAA PF00004.24 OAJ00989.1 - 1.9e-59 199.5 0.0 6.3e-45 152.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ00989.1 - 1.3e-08 35.6 0.0 0.01 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ00989.1 - 2.7e-07 30.7 5.5 0.013 15.5 0.1 4.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 OAJ00989.1 - 8.2e-07 28.9 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ00989.1 - 1.3e-05 25.5 0.0 0.19 12.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 OAJ00989.1 - 3.4e-05 23.9 0.2 0.0082 16.2 0.1 3.3 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ00989.1 - 9e-05 22.1 0.0 0.0079 15.9 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 OAJ00989.1 - 0.00011 21.9 0.0 0.024 14.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 OAJ00989.1 - 0.00036 19.9 0.5 0.0036 16.7 0.1 2.5 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 OAJ00989.1 - 0.0005 19.1 0.0 0.0066 15.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus CDC48_2 PF02933.12 OAJ00989.1 - 0.00071 19.1 0.0 0.081 12.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 OAJ00989.1 - 0.0012 18.6 0.0 0.24 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAJ00989.1 - 0.0018 18.2 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ00989.1 - 0.0019 17.6 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ00989.1 - 0.0019 17.0 0.0 0.037 12.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 OAJ00989.1 - 0.0022 17.4 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 OAJ00989.1 - 0.0023 17.1 0.1 0.0068 15.5 0.0 1.7 2 0 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.1 OAJ00989.1 - 0.0026 17.8 0.0 3.3 7.7 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_2 PF07724.9 OAJ00989.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 OAJ00989.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 OAJ00989.1 - 0.011 14.6 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 OAJ00989.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 OAJ00989.1 - 0.02 14.0 1.3 0.054 12.6 0.1 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 OAJ00989.1 - 0.032 13.8 0.3 3.6 7.2 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Cytidylate_kin2 PF13189.1 OAJ00989.1 - 0.044 13.6 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.17 OAJ00989.1 - 0.045 13.6 0.0 9.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PhoH PF02562.11 OAJ00989.1 - 0.047 12.9 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 OAJ00989.1 - 0.058 12.9 0.2 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 OAJ00989.1 - 0.066 12.8 0.0 0.63 9.6 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 OAJ00989.1 - 0.099 12.2 0.0 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 OAJ00989.1 - 0.23 10.2 0.0 1.7 7.4 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain NAD_binding_10 PF13460.1 OAJ00990.1 - 3.9e-17 62.8 0.0 5.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ00990.1 - 0.00038 19.9 0.0 0.0005 19.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAJ00990.1 - 0.0016 17.7 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family CHCH PF06747.8 OAJ00995.1 - 1.4e-05 24.8 5.3 2e-05 24.3 3.6 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 OAJ00995.1 - 3.4e-05 23.9 2.7 4.8e-05 23.4 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) NDUF_B7 PF05676.8 OAJ00995.1 - 0.00056 19.2 1.3 0.00074 18.8 0.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.12 OAJ00995.1 - 0.017 15.1 2.4 0.024 14.6 1.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 OAJ00995.1 - 0.46 10.3 5.1 7.2 6.4 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 OAJ00995.1 - 0.77 9.8 4.1 1.8 8.6 2.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 His_Phos_2 PF00328.17 OAJ01000.1 - 9.8e-43 146.7 0.0 2.2e-42 145.6 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glycophorin_A PF01102.13 OAJ01001.1 - 0.05 13.3 4.4 0.082 12.6 2.4 1.8 1 1 0 1 1 1 0 Glycophorin A Trypan_PARP PF05887.6 OAJ01002.1 - 0.14 11.9 9.6 0.22 11.3 6.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.18 OAJ01003.1 - 3.4e-11 42.5 21.0 0.00049 19.8 0.5 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ01003.1 - 2.9e-07 30.0 16.0 0.11 12.1 0.2 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ01003.1 - 1.3e-05 24.5 9.7 0.071 12.6 0.1 3.8 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ01003.1 - 1.6 8.2 12.5 2.2 7.8 0.2 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger EamA PF00892.15 OAJ01004.1 - 2.8e-05 24.1 3.0 2.8e-05 24.1 2.1 3.5 3 1 1 4 4 4 1 EamA-like transporter family PsaL PF02605.10 OAJ01004.1 - 0.024 14.1 1.3 0.11 12.0 0.3 2.5 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI Peptidase_C13 PF01650.13 OAJ01005.1 - 1.7e-43 148.7 0.3 2.3e-43 148.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family DUF1295 PF06966.7 OAJ01006.1 - 3.6e-42 144.2 0.8 6.3e-42 143.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 OAJ01006.1 - 0.00011 21.9 0.1 0.00011 21.9 0.1 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 OAJ01006.1 - 0.026 14.7 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ01006.1 - 0.039 14.0 0.1 0.039 14.0 0.1 2.7 4 1 0 4 4 4 0 Phospholipid methyltransferase FAD_binding_7 PF03441.9 OAJ01007.1 - 8.5e-90 300.7 0.1 1.3e-89 300.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ01007.1 - 1.1e-39 135.8 0.0 2e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 OAJ01007.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family MCM_bind PF09739.4 OAJ01009.1 - 3.9e-06 26.4 0.0 6.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor Racemase_4 PF13615.1 OAJ01009.1 - 0.00034 20.8 0.0 0.00073 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative alanine racemase Grp1_Fun34_YaaH PF01184.14 OAJ01010.1 - 3.1e-37 127.9 12.4 4.1e-37 127.5 8.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Aminotran_5 PF00266.14 OAJ01011.1 - 1.1e-89 300.8 0.0 1.6e-89 300.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DASH_Hsk3 PF08227.6 OAJ01012.1 - 2.5e-05 24.3 2.4 3.5e-05 23.8 1.7 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like SHQ1 PF04925.10 OAJ01013.1 - 1.6e-25 89.6 0.0 2.3e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein Pkinase PF00069.20 OAJ01014.1 - 2.8e-50 170.8 0.0 4.2e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01014.1 - 1.3e-23 83.4 0.0 2.8e-23 82.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAJ01014.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 OAJ01014.1 - 0.1 11.9 0.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Histidinol_dh PF00815.15 OAJ01015.1 - 1e-167 557.9 0.5 9.2e-150 498.8 0.5 2.2 1 1 1 2 2 2 2 Histidinol dehydrogenase PRA-CH PF01502.13 OAJ01015.1 - 5.2e-21 74.0 0.2 9.8e-21 73.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 OAJ01015.1 - 2.6e-11 43.6 0.6 6.7e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 OAJ01015.1 - 0.007 16.2 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PPI_Ypi1 PF07491.6 OAJ01016.1 - 1.2e-24 85.6 0.3 1.2e-24 85.6 0.2 2.1 3 0 0 3 3 3 1 Protein phosphatase inhibitor DUF3245 PF11595.3 OAJ01016.1 - 0.0056 16.9 1.3 0.0056 16.9 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3245) Gp5_C PF06715.7 OAJ01016.1 - 0.054 13.4 2.5 0.28 11.1 0.4 2.4 2 0 0 2 2 2 0 Gp5 C-terminal repeat (3 copies) RFXA_RFXANK_bdg PF15289.1 OAJ01016.1 - 7.5 6.7 7.2 0.78 9.9 1.3 2.0 2 1 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Med8 PF10232.4 OAJ01017.1 - 0.04 13.4 2.1 0.18 11.2 1.2 2.0 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 WD40 PF00400.27 OAJ01018.1 - 1.2e-32 110.6 15.2 5.4e-10 38.7 0.1 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 OAJ01018.1 - 2.5e-09 35.8 3.3 0.0018 16.5 0.0 4.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Cortex-I_coil PF09304.5 OAJ01018.1 - 0.93 9.5 4.6 1.6 8.8 3.2 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Senescence PF06911.7 OAJ01023.1 - 1.4e-26 93.3 1.8 2.7e-26 92.3 1.3 1.5 1 0 0 1 1 1 1 Senescence-associated protein PrpF PF04303.8 OAJ01025.1 - 4.1e-51 173.8 0.0 5.1e-37 127.4 0.0 2.2 2 0 0 2 2 2 2 PrpF protein Ribosomal_L2_C PF03947.13 OAJ01026.1 - 2.3e-44 150.3 4.6 2.1e-32 111.6 2.5 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAJ01026.1 - 2.7e-24 84.9 0.1 5.1e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain NIPSNAP PF07978.8 OAJ01027.1 - 2e-35 120.8 1.9 5.3e-28 96.9 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP DUF718 PF05336.8 OAJ01027.1 - 0.01 15.6 1.4 0.012 15.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Glyco_hydro_85 PF03644.8 OAJ01028.1 - 1.2e-78 264.4 0.0 1.8e-78 263.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Mito_carr PF00153.22 OAJ01029.1 - 3.7e-44 148.3 9.0 9.9e-17 60.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2417 PF10329.4 OAJ01030.1 - 6.2e-13 48.6 0.0 9.6e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Ribosomal_S24e PF01282.14 OAJ01031.1 - 1.4e-33 114.5 0.1 2.2e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e zf-H2C2_2 PF13465.1 OAJ01032.1 - 6.9e-24 82.9 19.6 2.2e-08 33.9 0.2 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ01032.1 - 2.9e-19 68.1 22.3 9e-05 22.5 0.3 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ01032.1 - 2.7e-11 42.9 21.8 0.001 19.2 0.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ01032.1 - 9e-05 22.5 3.3 0.11 12.6 0.0 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAJ01032.1 - 0.00021 21.0 13.4 0.00064 19.5 0.0 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 OAJ01032.1 - 0.16 12.2 12.2 6.4 7.1 0.1 4.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 OAJ01032.1 - 0.17 12.3 12.2 0.61 10.4 1.7 3.1 2 1 1 3 3 3 0 TRAF-type zinc finger GCD14 PF08704.5 OAJ01033.1 - 7.9e-73 244.9 7.6 2.2e-36 125.5 1.3 4.2 3 1 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 OAJ01033.1 - 0.0014 18.2 0.0 0.0035 16.9 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAJ01033.1 - 0.014 15.4 0.5 0.081 12.9 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain RrnaAD PF00398.15 OAJ01033.1 - 0.032 13.2 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GAPT PF11770.3 OAJ01034.1 - 0.057 13.0 0.6 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Lactamase_B_2 PF12706.2 OAJ01035.1 - 3.4e-26 91.9 0.0 1.8e-23 83.0 0.0 2.9 3 1 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ01035.1 - 4.6e-07 29.6 0.8 1.3e-06 28.2 0.0 2.3 3 0 0 3 3 3 1 Beta-lactamase superfamily domain DUF1640 PF07798.6 OAJ01036.1 - 3.1e-12 46.9 6.7 5.9e-12 45.9 4.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) OmpH PF03938.9 OAJ01036.1 - 0.0059 16.5 2.8 0.0059 16.5 2.0 1.9 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) SF-assemblin PF06705.6 OAJ01036.1 - 0.0083 15.2 4.3 0.014 14.5 3.0 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin Fzo_mitofusin PF04799.8 OAJ01036.1 - 0.2 11.0 2.1 0.37 10.1 1.4 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4404 PF14357.1 OAJ01036.1 - 0.24 11.8 5.5 0.79 10.1 2.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DAGK_cat PF00781.19 OAJ01037.1 - 4.7e-20 71.3 0.0 9.2e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Maf1 PF09174.5 OAJ01038.1 - 3.5 7.4 6.8 0.41 10.4 0.0 2.5 2 2 0 2 2 2 0 Maf1 regulator Ribosomal_L34e PF01199.13 OAJ01039.1 - 3.8e-34 116.7 6.6 4.3e-34 116.6 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 OAJ01039.1 - 0.0016 17.9 0.2 0.0024 17.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c7 Cytochrome_C554 PF13435.1 OAJ01039.1 - 0.05 13.6 0.3 0.065 13.2 0.2 1.3 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 OAJ01039.1 - 0.052 13.8 0.2 0.079 13.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c3 DUF2199 PF09965.4 OAJ01039.1 - 0.075 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Mob_synth_C PF06463.8 OAJ01039.1 - 0.1 12.2 0.6 9.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C FhuF_C PF11575.3 OAJ01039.1 - 0.78 9.4 4.0 6.2 6.5 0.1 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain CAP PF00188.21 OAJ01040.1 - 1.7e-23 83.4 3.3 2.7e-23 82.7 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KIP1 PF07765.7 OAJ01041.1 - 0.017 14.9 0.1 0.045 13.5 0.1 1.7 1 0 0 1 1 1 0 KIP1-like protein Sec39 PF08314.6 OAJ01041.1 - 0.066 11.1 0.1 0.066 11.1 0.1 1.8 2 0 0 2 2 2 0 Secretory pathway protein Sec39 CHAD PF05235.9 OAJ01046.1 - 0.011 15.3 0.2 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 CHAD domain Microtub_assoc PF07989.6 OAJ01046.1 - 0.011 15.5 0.1 0.035 13.9 0.0 2.0 1 1 0 1 1 1 0 Microtubule associated Nro1 PF12753.2 OAJ01046.1 - 0.15 11.0 0.7 0.19 10.6 0.4 1.3 1 1 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF4164 PF13747.1 OAJ01046.1 - 0.37 10.9 6.1 0.9 9.7 1.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) PIF1 PF05970.9 OAJ01047.1 - 1.4e-18 66.9 0.0 2.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01047.1 - 2.3e-10 40.3 0.3 9.3e-09 35.1 0.0 2.6 1 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ01047.1 - 1.6e-07 31.2 0.0 3.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ01047.1 - 3.3e-06 26.7 1.2 8.7e-06 25.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 OAJ01047.1 - 0.022 14.8 0.0 0.071 13.2 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 OAJ01047.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 OAJ01047.1 - 0.059 12.9 0.0 13 5.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain Histone PF00125.19 OAJ01055.1 - 9.1e-12 44.9 0.1 1.3e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 OAJ01055.1 - 4.2e-05 23.4 0.0 7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 OAJ01055.1 - 4.4e-05 23.4 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 OAJ01055.1 - 0.0014 18.7 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ01055.1 - 0.003 16.8 0.1 0.006 15.8 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 OAJ01055.1 - 0.038 13.7 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF4095 PF13338.1 OAJ01055.1 - 0.055 13.6 0.5 0.09 12.9 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4095) Carla_C4 PF01623.12 OAJ01055.1 - 0.12 12.1 1.6 0.15 11.8 0.8 1.4 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein NTP_transf_2 PF01909.18 OAJ01056.1 - 2.3e-06 27.8 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 OAJ01056.1 - 0.54 10.2 1.9 3.6 7.6 0.4 2.7 2 1 0 2 2 2 0 Cid1 family poly A polymerase Amidohydro_1 PF01979.15 OAJ01057.1 - 1.4e-40 139.9 0.0 3.1e-38 132.2 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 OAJ01057.1 - 9.1e-08 31.7 0.2 0.00033 19.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 OAJ01057.1 - 3.9e-06 26.5 0.0 9.5e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 OAJ01057.1 - 0.0016 17.4 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 OAJ01057.1 - 0.0045 17.0 0.9 0.15 12.0 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase Pkinase PF00069.20 OAJ01058.1 - 7.2e-64 215.4 0.0 1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01058.1 - 3.3e-52 177.1 0.0 5.2e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 OAJ01058.1 - 9.4e-05 22.0 10.2 0.00015 21.3 7.0 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 OAJ01058.1 - 0.00085 18.3 0.0 0.0054 15.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like CH PF00307.26 OAJ01058.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 OAJ01058.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 CDC24 Calponin RIO1 PF01163.17 OAJ01058.1 - 0.13 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 OAJ01058.1 - 0.14 10.9 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PHD_3 PF13922.1 OAJ01058.1 - 0.73 10.1 6.6 2.1 8.6 4.6 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD PF00628.24 OAJ01058.1 - 1.4 8.6 10.1 2.5 7.8 7.0 1.4 1 0 0 1 1 1 0 PHD-finger TPR_12 PF13424.1 OAJ01059.1 - 3.4e-06 26.9 6.8 0.028 14.3 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ01059.1 - 0.001 18.6 0.0 11 6.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ01059.1 - 0.0012 18.4 3.9 6.2 6.5 0.1 4.2 3 2 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 OAJ01059.1 - 0.0045 16.8 12.6 0.1 12.5 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ01059.1 - 0.0086 16.7 14.4 1.4 9.6 0.7 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ01059.1 - 0.029 13.9 6.5 2 8.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.21 OAJ01060.1 - 2.7e-10 39.9 10.1 3.4e-05 23.9 1.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ01060.1 - 5.6e-07 29.4 10.0 0.0046 17.2 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ01060.1 - 3.8e-06 26.9 2.0 3.8e-06 26.9 1.4 3.0 3 0 0 3 3 3 1 Zinc-finger double domain DUF3395 PF11875.3 OAJ01061.1 - 2.4e-32 111.6 0.0 4.4e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 OAJ01061.1 - 8.9e-21 73.4 0.6 1.8e-20 72.3 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 OAJ01065.1 - 3.5e-44 148.4 10.8 2e-17 62.6 0.7 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EBP PF05241.7 OAJ01066.1 - 4.4e-57 192.2 9.8 5.4e-57 191.9 6.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein HR_lesion PF05514.6 OAJ01066.1 - 0.014 15.2 1.6 0.48 10.2 0.1 2.4 2 0 0 2 2 2 0 HR-like lesion-inducing NAD_binding_8 PF13450.1 OAJ01066.1 - 0.041 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF788 PF05620.6 OAJ01066.1 - 1.2 9.0 6.0 0.37 10.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Peptidase_M16 PF00675.15 OAJ01067.1 - 8.8e-54 181.3 1.3 1.1e-52 177.7 0.5 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ01067.1 - 3.2e-44 150.8 0.0 6.1e-41 140.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain zf-C3HC4_2 PF13923.1 OAJ01068.1 - 1.5e-08 34.5 1.8 1.5e-08 34.5 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ01068.1 - 5e-08 32.4 1.8 5e-08 32.4 1.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ01068.1 - 1.1e-06 28.3 5.9 1.2e-06 28.1 1.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ01068.1 - 1.2e-06 28.1 1.7 3e-05 23.5 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ01068.1 - 0.00025 20.8 1.9 0.0005 19.8 1.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 OAJ01068.1 - 0.00031 20.4 2.3 0.00031 20.4 1.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ01068.1 - 0.00076 19.1 2.1 0.0015 18.2 1.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger DUF1644 PF07800.7 OAJ01068.1 - 0.35 10.7 2.5 5.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-Apc11 PF12861.2 OAJ01068.1 - 2 8.2 2.9 5.3 6.9 0.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cnd3 PF12719.2 OAJ01070.1 - 4.2e-76 255.7 0.0 1.5e-74 250.6 0.0 2.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 OAJ01070.1 - 1.5e-05 25.1 13.1 0.0088 16.3 0.3 6.2 5 1 2 7 7 7 4 HEAT repeats HEAT PF02985.17 OAJ01070.1 - 0.00091 19.1 3.7 23 5.4 0.0 6.7 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.2 OAJ01070.1 - 0.049 13.4 2.3 0.36 10.6 0.1 3.1 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Herpes_gE PF02480.11 OAJ01071.1 - 0.033 12.4 0.0 0.033 12.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CcoS PF03597.10 OAJ01071.1 - 5.8 6.4 6.4 13 5.3 1.5 2.2 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Homeobox PF00046.24 OAJ01072.1 - 5.6e-19 67.5 3.9 1.5e-18 66.1 2.7 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAJ01072.1 - 1 9.1 3.3 2.1 8.1 0.3 2.4 2 0 0 2 2 2 0 Homeobox KN domain Rad4 PF03835.10 OAJ01073.1 - 5.6e-27 93.9 0.0 5.6e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 OAJ01073.1 - 7.2e-25 86.5 0.2 1.5e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 OAJ01073.1 - 6.4e-19 67.2 0.1 1.2e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 OAJ01073.1 - 3.6e-09 36.8 0.0 3.6e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily BHD_2 PF10404.4 OAJ01073.1 - 0.0085 16.3 0.2 0.0085 16.3 0.1 3.2 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 BCS1_N PF08740.6 OAJ01074.1 - 1e-48 165.4 0.0 2.1e-48 164.3 0.0 1.6 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 OAJ01074.1 - 2.4e-17 63.3 0.0 1.9e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 OAJ01074.1 - 0.00016 20.6 0.0 0.00036 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAJ01074.1 - 0.00027 21.7 0.0 0.00076 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ01074.1 - 0.0019 18.2 0.1 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 OAJ01074.1 - 0.0019 17.6 1.3 0.021 14.2 0.0 3.1 4 1 0 4 4 4 1 AAA domain AAA_21 PF13304.1 OAJ01074.1 - 0.0034 17.3 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ01074.1 - 0.0041 16.6 0.0 0.0094 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 OAJ01074.1 - 0.0071 16.2 0.0 0.021 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ01074.1 - 0.0098 16.0 0.0 0.04 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ01074.1 - 0.029 14.0 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 OAJ01074.1 - 0.032 14.5 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 OAJ01074.1 - 0.09 12.3 0.1 0.31 10.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ01074.1 - 0.13 12.5 0.0 1.1 9.5 0.0 2.3 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.7 OAJ01074.1 - 0.16 11.0 0.0 0.36 9.8 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 OAJ01074.1 - 0.17 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 OAJ01074.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PDZ_2 PF13180.1 OAJ01075.1 - 8.9e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 OAJ01075.1 - 0.00027 21.0 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 OAJ01075.1 - 0.0031 17.4 0.0 0.0083 16.1 0.0 1.6 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain Gag_spuma PF03276.9 OAJ01075.1 - 0.017 13.4 0.4 0.021 13.2 0.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein PTPlike_phytase PF14566.1 OAJ01076.1 - 4.4e-117 387.0 0.5 1.6e-41 141.7 0.0 4.3 4 0 0 4 4 4 4 Inositol hexakisphosphate DSPc PF00782.15 OAJ01076.1 - 0.0003 20.3 0.0 2.2 7.8 0.0 3.5 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain TFIIE-A_C-term PF11521.3 OAJ01076.1 - 0.0013 18.6 3.9 2.7 7.9 0.0 5.0 5 0 0 5 5 5 1 C-terminal general transcription factor TFIIE alpha Y_phosphatase PF00102.22 OAJ01076.1 - 0.049 12.9 0.2 26 4.0 0.0 3.1 3 0 0 3 3 3 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 OAJ01076.1 - 0.2 11.0 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Cnd1_N PF12922.2 OAJ01076.1 - 0.87 9.2 3.9 5.3 6.6 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1, N-term Transket_pyr PF02779.19 OAJ01077.1 - 5e-60 202.0 0.0 7.4e-60 201.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ01077.1 - 6.6e-58 195.7 0.0 1e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Tyrosinase PF00264.15 OAJ01078.1 - 0.00021 21.4 4.9 0.00023 21.3 0.0 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase BSD PF03909.12 OAJ01079.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 BSD domain Tyrosinase PF00264.15 OAJ01080.1 - 1.4e-34 120.2 2.7 1.9e-34 119.7 1.8 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PTPlike_phytase PF14566.1 OAJ01081.1 - 1.1e-16 61.2 0.0 1.3e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF2439 PF10382.4 OAJ01086.1 - 1.3e-07 31.6 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) NUDIX PF00293.23 OAJ01087.1 - 1.5e-09 37.6 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pox_RNA_pol PF03293.9 OAJ01087.1 - 0.028 13.9 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Cupin_8 PF13621.1 OAJ01088.1 - 8.2e-18 64.8 0.0 1.3e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 OAJ01088.1 - 9.1e-18 64.5 0.1 5.1e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 OAJ01088.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) SecY PF00344.15 OAJ01089.1 - 1.8e-98 329.6 9.1 2.2e-98 329.3 6.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 OAJ01089.1 - 3.3e-17 61.6 0.3 1.1e-16 60.0 0.2 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.6 OAJ01089.1 - 0.78 9.4 5.7 1.2 8.8 0.0 3.4 3 1 0 3 3 3 0 Tight junction protein, Claudin-like tRNA-synt_1 PF00133.17 OAJ01091.1 - 8.6e-155 516.1 0.0 1.2e-154 515.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ01091.1 - 2e-28 99.0 0.0 3.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ01091.1 - 1.1e-21 76.9 0.1 7.8e-11 41.2 0.0 4.4 4 0 0 4 4 4 4 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 OAJ01091.1 - 0.00016 21.2 6.6 0.00039 19.9 4.6 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 OAJ01091.1 - 0.00058 19.1 0.0 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 OAJ01091.1 - 0.049 12.7 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ycf9 PF01737.12 OAJ01091.1 - 0.085 12.3 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 YCF9 Mpv17_PMP22 PF04117.7 OAJ01092.1 - 1.6e-24 85.2 4.8 3e-24 84.4 3.3 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Sars6 PF12133.3 OAJ01092.1 - 0.12 12.0 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Coatomer_E PF04733.9 OAJ01094.1 - 7.2e-45 153.3 7.2 9.1e-45 153.0 5.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 OAJ01094.1 - 0.00096 18.7 1.4 0.00096 18.7 1.0 3.3 4 1 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 OAJ01094.1 - 0.003 17.8 22.4 0.016 15.5 4.7 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ01094.1 - 0.15 12.7 19.3 5.3 7.9 2.5 5.5 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01094.1 - 2.2 8.4 16.4 4 7.6 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Med3 PF11593.3 OAJ01095.1 - 1.1 8.3 5.2 1.9 7.6 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RVT_1 PF00078.22 OAJ01096.1 - 1.1e-17 64.1 0.0 2.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01096.1 - 1.2e-15 57.7 0.0 2.4e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ01096.1 - 0.00023 21.6 0.2 0.0018 18.7 0.1 2.4 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ01096.1 - 0.014 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ01096.1 - 0.02 14.7 0.1 0.074 12.8 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Phospholip_B PF04916.8 OAJ01096.1 - 0.63 8.0 0.0 1.1 7.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B Hemerythrin PF01814.18 OAJ01097.1 - 1.5e-11 44.5 5.3 4.2e-10 39.9 3.7 2.1 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain WD40 PF00400.27 OAJ01098.1 - 1.5e-13 50.0 18.5 1.8e-05 24.4 0.1 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat DHHA1 PF02272.14 OAJ01098.1 - 0.0029 17.2 0.6 0.0086 15.7 0.4 1.7 1 0 0 1 1 1 1 DHHA1 domain RWD PF05773.17 OAJ01098.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Phage_integrase PF00589.17 OAJ01100.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ01101.1 - 0.0015 17.9 0.0 0.0077 15.6 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1697 PF08002.6 OAJ01104.1 - 0.066 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) DUF3754 PF12576.3 OAJ01104.1 - 0.11 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) CENP-Q PF13094.1 OAJ01108.1 - 0.0098 15.9 1.2 0.33 10.9 0.0 2.6 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit PrmA PF06325.8 OAJ01108.1 - 0.058 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Prominin PF05478.6 OAJ01108.1 - 0.06 10.8 0.3 0.12 9.8 0.0 1.5 1 1 0 1 1 1 0 Prominin Nnf1 PF03980.9 OAJ01108.1 - 0.07 13.1 3.3 0.27 11.2 0.5 2.1 1 1 0 2 2 2 0 Nnf1 CENP-Q PF13094.1 OAJ01110.1 - 0.0098 15.9 1.2 0.33 10.9 0.0 2.6 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit PrmA PF06325.8 OAJ01110.1 - 0.058 12.5 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Prominin PF05478.6 OAJ01110.1 - 0.06 10.8 0.3 0.12 9.8 0.0 1.5 1 1 0 1 1 1 0 Prominin Nnf1 PF03980.9 OAJ01110.1 - 0.07 13.1 3.3 0.27 11.2 0.5 2.1 1 1 0 2 2 2 0 Nnf1 Helitron_like_N PF14214.1 OAJ01111.1 - 0.00011 21.9 0.0 0.00058 19.6 0.0 2.3 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus Bunya_RdRp PF04196.7 OAJ01111.1 - 0.17 9.8 0.0 0.25 9.3 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase HSP70 PF00012.15 OAJ01112.1 - 6e-58 196.1 7.3 1.5e-27 95.7 0.3 3.1 1 1 2 3 3 3 3 Hsp70 protein Hydantoinase_A PF01968.13 OAJ01112.1 - 0.0018 17.4 0.1 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase PIF1 PF05970.9 OAJ01113.1 - 4.9e-22 78.3 0.1 1.2e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase HSP70 PF00012.15 OAJ01113.1 - 1.2e-16 59.7 0.0 1.7e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein AAA_30 PF13604.1 OAJ01113.1 - 2.8e-12 46.6 0.0 7.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ01113.1 - 2.6e-06 27.0 0.1 7.7e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ01113.1 - 0.0014 18.6 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Helitron_like_N PF14214.1 OAJ01113.1 - 0.0018 18.0 0.1 0.0059 16.3 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_22 PF13401.1 OAJ01113.1 - 0.0021 18.1 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ01113.1 - 0.0065 16.2 0.6 0.046 13.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bunya_RdRp PF04196.7 OAJ01113.1 - 0.28 9.1 0.0 0.4 8.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase GTP_EFTU PF00009.22 OAJ01114.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AT_hook PF02178.14 OAJ01115.1 - 0.43 10.4 8.0 1.6 8.6 5.5 2.0 1 0 0 1 1 1 0 AT hook motif Tub_2 PF04525.7 OAJ01117.1 - 1e-18 67.4 0.0 1.2e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 G6PD_C PF02781.11 OAJ01118.1 - 2.3e-122 407.4 0.0 2.9e-122 407.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 OAJ01118.1 - 3.8e-62 209.7 0.1 9.4e-62 208.4 0.1 1.6 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain OPT PF03169.10 OAJ01120.1 - 1.8e-173 578.3 54.9 2e-173 578.1 38.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_16 PF00722.16 OAJ01121.1 - 4.7e-32 110.7 1.3 9.4e-32 109.7 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 OAJ01121.1 - 0.0018 18.1 17.3 0.0042 17.0 12.0 1.6 1 0 0 1 1 1 1 Chitin recognition protein Allantoicase PF03561.10 OAJ01123.1 - 9.2e-84 278.4 0.0 1.9e-42 144.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 OAJ01123.1 - 2.6e-45 153.7 0.0 3.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase DUF2985 PF11204.3 OAJ01124.1 - 8.7e-28 95.8 3.7 1.6e-27 95.1 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.1 OAJ01124.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 0 Putative sensor Condensation PF00668.15 OAJ01125.1 - 9.7e-77 257.7 0.9 1.4e-37 129.1 0.6 2.2 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 OAJ01125.1 - 1.1e-15 57.5 0.0 2.2e-07 31.0 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site MFS_1 PF07690.11 OAJ01126.1 - 6.9e-14 51.3 10.9 6.9e-14 51.3 7.5 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 OAJ01131.1 - 4.5e-62 209.5 0.0 4.3e-34 117.8 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01131.1 - 4.6e-23 81.6 0.0 6.3e-20 71.3 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase NAP PF00956.13 OAJ01133.1 - 5.1e-29 101.1 8.0 2.1e-28 99.1 5.5 1.9 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Voldacs PF03517.8 OAJ01133.1 - 0.27 11.0 3.1 0.37 10.6 2.1 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling RXT2_N PF08595.6 OAJ01133.1 - 5.5 6.7 7.6 16 5.3 2.4 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal RA PF00788.18 OAJ01134.1 - 3.5e-15 56.2 0.1 8.4e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ01134.1 - 8e-13 47.5 0.6 2.4e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 SH3 domain SAM_2 PF07647.12 OAJ01134.1 - 1.6e-12 47.0 0.0 2.5e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ01134.1 - 1.6e-11 44.2 0.0 2.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 OAJ01134.1 - 1.5e-07 30.7 1.2 2.3e-05 23.7 0.0 3.1 2 1 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 OAJ01134.1 - 3.4e-07 29.7 6.3 0.0034 16.9 0.2 3.0 3 0 0 3 3 3 2 Variant SH3 domain RRM_1 PF00076.17 OAJ01135.1 - 3.5e-30 103.4 0.0 2.6e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ01135.1 - 2.5e-23 81.8 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ01135.1 - 1.1e-16 60.4 0.0 2.6e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ01135.1 - 0.00022 20.9 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif DbpA PF03880.10 OAJ01135.1 - 0.0038 16.8 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 1 DbpA RNA binding domain SCO1-SenC PF02630.9 OAJ01136.1 - 3.2e-54 183.1 0.0 4.4e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 OAJ01136.1 - 0.014 15.1 0.0 0.038 13.6 0.0 1.8 1 1 0 1 1 1 0 AhpC/TSA family TFIIE_beta PF02186.10 OAJ01137.1 - 0.00087 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain Glyco_hydro_18 PF00704.23 OAJ01138.1 - 2.2e-56 191.7 0.5 3e-56 191.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 HAD_2 PF13419.1 OAJ01139.1 - 2.5e-17 63.6 0.0 3.6e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ01139.1 - 9.2e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAJ01139.1 - 0.00011 22.7 0.0 0.00025 21.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RNase_H PF00075.19 OAJ01141.1 - 4.2e-09 36.8 0.0 6.9e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ01141.1 - 2.3e-05 24.0 0.0 5.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase-like DDE_Tnp_4 PF13359.1 OAJ01142.1 - 1.9e-36 125.0 0.0 2.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ01142.1 - 3.5e-11 42.8 0.0 6.1e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ01142.1 - 0.00022 20.8 0.0 0.0029 17.1 0.0 2.2 1 1 0 1 1 1 1 Transposase DDE domain ATG16 PF08614.6 OAJ01144.1 - 1.7e-45 155.2 20.5 2.2e-45 154.8 14.2 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) LURAP PF14854.1 OAJ01144.1 - 0.034 13.8 0.3 0.12 12.0 0.1 2.0 1 1 0 1 1 1 0 Leucine rich adaptor protein DUF2388 PF09498.5 OAJ01144.1 - 0.094 12.3 3.2 2 8.1 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2388) FlgN PF05130.7 OAJ01144.1 - 0.14 12.3 21.5 0.15 12.3 11.5 2.3 1 1 1 2 2 2 0 FlgN protein ORF6N PF10543.4 OAJ01144.1 - 0.27 11.2 1.5 0.53 10.3 0.5 2.0 2 1 0 2 2 2 0 ORF6N domain YtxH PF12732.2 OAJ01144.1 - 0.36 11.2 2.2 2.8 8.3 0.1 2.6 1 1 1 2 2 2 0 YtxH-like protein Fib_alpha PF08702.5 OAJ01144.1 - 0.9 9.6 11.0 0.051 13.7 3.7 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 OAJ01144.1 - 1.8 6.9 6.1 2.2 6.6 4.2 1.1 1 0 0 1 1 1 0 AAA domain DUF724 PF05266.9 OAJ01144.1 - 2.7 7.5 7.6 7.9 6.0 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ATP-synt_ab PF00006.20 OAJ01145.1 - 8.8e-111 368.5 0.0 1.4e-110 367.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ01145.1 - 6.9e-22 78.0 0.2 1.4e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ01145.1 - 7.9e-14 51.6 3.4 2.8e-13 49.8 2.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 OAJ01145.1 - 0.031 14.1 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ras PF00071.17 OAJ01146.1 - 3.7e-57 192.2 0.1 4.4e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ01146.1 - 8.9e-19 68.1 0.0 1.9e-18 67.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 OAJ01146.1 - 3.9e-14 52.2 0.0 4.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ01146.1 - 9.4e-08 31.6 0.0 1.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ01146.1 - 2.6e-07 30.5 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 OAJ01146.1 - 7.1e-07 28.6 0.1 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 OAJ01146.1 - 0.00033 20.2 0.6 0.017 14.7 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 OAJ01146.1 - 0.0005 20.2 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ01146.1 - 0.0012 18.0 0.1 0.0029 16.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAJ01146.1 - 0.0016 17.8 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 OAJ01146.1 - 0.0035 16.4 0.2 0.053 12.5 0.0 2.3 2 1 0 2 2 2 1 Septin AAA_16 PF13191.1 OAJ01146.1 - 0.0043 17.0 0.0 0.02 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 OAJ01146.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ01146.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 OAJ01146.1 - 0.0076 15.7 0.0 0.031 13.7 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 OAJ01146.1 - 0.01 15.2 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 OAJ01146.1 - 0.017 14.3 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 OAJ01146.1 - 0.017 14.8 0.0 0.06 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 OAJ01146.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 OAJ01146.1 - 0.033 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ01146.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 OAJ01146.1 - 0.097 11.9 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B FtsX PF02687.16 OAJ01147.1 - 0.22 11.3 1.5 0.33 10.7 1.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family Glyco_hydro_20 PF00728.17 OAJ01148.1 - 1.7e-23 83.4 0.0 3.4e-23 82.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain MMS19_N PF14500.1 OAJ01149.1 - 2.5e-63 213.7 0.0 7.1e-53 179.5 0.0 2.6 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 OAJ01149.1 - 3.4e-36 124.8 0.6 8.5e-35 120.2 0.0 2.9 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal DUF1546 PF07571.8 OAJ01149.1 - 0.0044 17.1 0.9 0.05 13.7 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) BSP_II PF05432.6 OAJ01149.1 - 0.02 14.2 0.4 0.039 13.2 0.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Coq4 PF05019.8 OAJ01150.1 - 4.4e-82 274.3 0.0 5.5e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 RNase_T PF00929.19 OAJ01151.1 - 1.7e-24 86.9 0.0 2.5e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 OAJ01151.1 - 0.00027 20.4 0.0 0.0011 18.5 0.0 1.9 2 1 0 2 2 2 1 3'-5' exonuclease OHCU_decarbox PF09349.5 OAJ01152.1 - 1.3e-25 90.5 0.0 2.7e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase DUF2360 PF10152.4 OAJ01152.1 - 7.3 6.8 9.4 4.7 7.4 0.3 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MutS_V PF00488.16 OAJ01153.1 - 1.1e-62 211.4 0.0 2e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ01153.1 - 3.5e-31 108.5 7.3 3.5e-31 108.5 5.1 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 OAJ01153.1 - 1.3e-05 25.3 0.1 0.0082 16.2 0.0 3.3 3 0 0 3 3 3 2 MutS domain II MutS_IV PF05190.13 OAJ01153.1 - 6.3e-05 23.0 0.4 6.3e-05 23.0 0.2 2.3 3 0 0 3 3 3 1 MutS family domain IV AAA_29 PF13555.1 OAJ01153.1 - 0.008 15.6 0.4 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ01153.1 - 0.0082 15.5 0.1 0.1 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 OAJ01153.1 - 1 9.6 0.0 1 9.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain zf-BED PF02892.10 OAJ01156.1 - 0.029 14.1 3.1 0.058 13.1 2.2 1.5 1 0 0 1 1 1 0 BED zinc finger Ras PF00071.17 OAJ01158.1 - 4.8e-44 149.5 0.0 7.5e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Ras family WD40 PF00400.27 OAJ01158.1 - 7.2e-18 63.7 8.9 2.1e-07 30.5 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Miro PF08477.8 OAJ01158.1 - 1.4e-07 32.0 0.0 3.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Nup160 PF11715.3 OAJ01158.1 - 0.0077 14.4 0.1 0.012 13.8 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 OPT PF03169.10 OAJ01159.1 - 8.5e-94 315.1 42.4 9.8e-94 314.9 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3353 PF11833.3 OAJ01159.1 - 0.054 12.9 1.9 0.29 10.5 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) Pkinase PF00069.20 OAJ01160.1 - 1.4e-61 207.9 0.0 1.8e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01160.1 - 4.2e-43 147.2 0.0 5.7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01160.1 - 3.4e-07 29.5 0.0 5.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ01160.1 - 5.9e-06 26.1 0.4 0.015 15.0 0.0 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 OAJ01160.1 - 0.23 10.4 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family THUMP PF02926.12 OAJ01161.1 - 1.5e-14 54.1 0.1 3.5e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 THUMP domain Polysacc_deac_1 PF01522.16 OAJ01162.1 - 2e-23 82.3 0.0 3.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.20 OAJ01164.1 - 3.5e-38 131.2 0.0 4.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01164.1 - 5.8e-17 61.6 0.0 8.7e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ01164.1 - 0.0045 16.0 0.1 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 OAJ01164.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RTC4 PF14474.1 OAJ01164.1 - 0.13 12.1 0.0 0.48 10.3 0.0 1.9 1 1 0 1 1 1 0 RTC4-like domain DEAD PF00270.24 OAJ01166.1 - 1.9e-33 115.3 0.2 3.2e-32 111.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01166.1 - 3.3e-25 87.7 0.2 5.7e-25 86.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 OAJ01166.1 - 0.00033 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain CDC27 PF09507.5 OAJ01167.1 - 3e-34 119.0 77.7 1.7e-21 76.9 0.0 3.9 2 1 1 3 3 3 3 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 OAJ01167.1 - 0.0019 16.7 58.1 0.0026 16.2 40.3 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Serglycin PF04360.7 OAJ01167.1 - 0.069 12.8 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Serglycin PAT1 PF09770.4 OAJ01167.1 - 1.1 7.4 21.9 1.5 6.9 15.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-protein PF00469.15 OAJ01167.1 - 1.1 8.5 13.4 2.4 7.4 9.3 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Mitofilin PF09731.4 OAJ01167.1 - 3.7 6.0 40.2 5.5 5.5 27.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF966 PF06136.8 OAJ01167.1 - 8.2 5.7 26.4 7.4 5.8 16.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) AFG1_ATPase PF03969.11 OAJ01168.1 - 6.1e-85 285.1 0.0 3.7e-81 272.7 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 OAJ01168.1 - 0.00014 21.9 0.0 0.00062 19.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ01168.1 - 0.004 17.1 0.0 0.036 14.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 OAJ01168.1 - 0.007 16.5 0.0 0.092 12.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LIME1 PF15332.1 OAJ01168.1 - 0.043 13.0 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Lck-interacting transmembrane adapter 1 UvrD-helicase PF00580.16 OAJ01168.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Antimicrobial19 PF08225.6 OAJ01168.1 - 0.14 11.5 0.4 0.3 10.5 0.3 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DEAD PF00270.24 OAJ01169.1 - 2.4e-44 150.7 0.0 1.4e-43 148.2 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01169.1 - 5.7e-23 80.5 0.0 2e-22 78.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01169.1 - 0.0013 18.6 0.0 0.011 15.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2285 PF10074.4 OAJ01169.1 - 0.003 17.8 2.1 0.059 13.7 0.4 2.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2285) CMS1 PF14617.1 OAJ01169.1 - 0.041 12.9 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit zf-CCHC_2 PF13696.1 OAJ01169.1 - 0.17 11.3 1.1 0.45 10.0 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 OAJ01169.1 - 0.18 11.7 1.8 0.31 11.0 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ01169.1 - 0.23 11.1 1.3 0.53 10.0 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle AD PF09793.4 OAJ01170.1 - 7.7e-19 67.3 0.0 1.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain SUI1 PF01253.17 OAJ01171.1 - 2.1e-17 62.6 0.0 4.9e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 RhoGEF PF00621.15 OAJ01174.1 - 1.9e-29 102.8 0.0 3.8e-24 85.5 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain DUF4547 PF15080.1 OAJ01174.1 - 1.9 7.8 0.0 3.1 7.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) 3-HAO PF06052.7 OAJ01175.1 - 2.1e-58 196.0 0.0 2.4e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 OAJ01175.1 - 1.3e-06 27.7 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 OAJ01175.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Cupin 2OG-FeII_Oxy_5 PF13759.1 OAJ01175.1 - 0.15 12.3 0.0 0.48 10.7 0.0 1.8 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase adh_short PF00106.20 OAJ01176.1 - 6.2e-17 62.0 0.1 9.3e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ01176.1 - 4.1e-07 29.8 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ01176.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ01176.1 - 0.00041 19.8 0.0 0.00075 19.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2877 PF11392.3 OAJ01176.1 - 0.0051 17.0 0.1 0.0093 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2877) adh_short_C2 PF13561.1 OAJ01176.1 - 0.022 14.5 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 OAJ01176.1 - 0.08 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GATA PF00320.22 OAJ01177.1 - 2.5e-11 42.6 12.3 1.5e-05 24.2 1.8 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAJ01177.1 - 0.65 9.3 6.7 2.6 7.4 0.1 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding GalP_UDP_transf PF01087.17 OAJ01179.1 - 6.8e-60 202.2 0.2 1.1e-59 201.5 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 OAJ01179.1 - 1.4e-40 138.5 0.0 5.7e-21 74.7 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain Retrotrans_gag PF03732.12 OAJ01180.1 - 0.03 14.3 0.0 0.12 12.4 0.0 2.1 1 0 0 1 1 1 0 Retrotransposon gag protein Ribonuclease_3 PF00636.21 OAJ01183.1 - 1.8e-15 57.3 0.0 5.2e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ01183.1 - 2.5e-05 24.2 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease-III-like DUF1840 PF08895.6 OAJ01183.1 - 0.03 14.3 0.5 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) His_Phos_1 PF00300.17 OAJ01184.1 - 2.1e-40 138.4 0.0 2.5e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.13 OAJ01185.1 - 1.4e-55 187.6 1.2 2.6e-55 186.8 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ01185.1 - 1.7e-34 118.0 0.0 4.7e-34 116.6 0.0 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 OAJ01185.1 - 2.3e-05 24.1 0.7 4e-05 23.4 0.5 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.6 OAJ01185.1 - 0.0029 16.8 0.4 0.012 14.7 0.0 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF1188) Saccharop_dh PF03435.13 OAJ01185.1 - 0.0053 15.7 0.2 0.007 15.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 OAJ01185.1 - 0.0064 15.8 0.8 0.033 13.5 0.4 2.2 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 OAJ01185.1 - 0.034 14.0 2.0 0.16 11.8 1.4 2.0 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rrf2 PF02082.15 OAJ01185.1 - 0.039 14.0 0.3 18 5.5 0.0 3.3 4 0 0 4 4 4 0 Transcriptional regulator Esterase_phd PF10503.4 OAJ01185.1 - 0.06 12.5 0.9 0.11 11.7 0.6 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase DapB_N PF01113.15 OAJ01185.1 - 0.06 13.2 1.7 0.18 11.7 0.6 2.3 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Git3 PF11710.3 OAJ01186.1 - 1.1e-09 38.1 9.2 2.5e-09 36.9 6.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 OAJ01186.1 - 1.1e-07 31.2 0.0 2.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 OAJ01186.1 - 0.018 14.7 0.1 0.057 13.1 0.0 1.9 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term YqzE PF14038.1 OAJ01186.1 - 0.083 12.6 0.0 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 YqzE-like protein Glyco_transf_7N PF13733.1 OAJ01187.1 - 0.26 10.6 0.0 0.48 9.7 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 COX6A PF02046.10 OAJ01188.1 - 2.3e-29 101.6 0.0 2.7e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF2278 PF10042.4 OAJ01188.1 - 0.099 12.3 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Abhydrolase_1 PF00561.15 OAJ01189.1 - 2e-25 89.6 0.1 2.8e-12 46.7 0.0 3.3 3 0 0 3 3 3 3 alpha/beta hydrolase fold H_lectin PF09458.5 OAJ01191.1 - 6e-22 77.0 0.0 2e-09 36.9 0.0 3.5 3 0 0 3 3 3 2 H-type lectin domain Xpo1 PF08389.7 OAJ01196.1 - 4.9e-15 55.7 0.0 3.2e-13 49.8 0.0 3.0 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.1 OAJ01196.1 - 0.00065 19.9 0.9 0.012 15.8 0.1 3.3 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 OAJ01196.1 - 0.0037 17.1 0.4 3.2 7.5 0.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ01196.1 - 0.0043 17.0 0.5 0.43 10.7 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat DUF3295 PF11702.3 OAJ01197.1 - 4.4e-11 42.4 0.3 4.4e-11 42.4 0.2 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF3295) RRM_1 PF00076.17 OAJ01198.1 - 9.8e-15 53.9 0.0 1.6e-06 27.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ01198.1 - 2.1e-12 46.8 0.1 5.3e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ01198.1 - 3.3e-06 26.8 0.1 0.00017 21.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAF PF02969.12 OAJ01199.1 - 9.2e-23 79.9 0.1 2e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 OAJ01199.1 - 2.4e-13 49.9 0.3 4.7e-12 45.8 0.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 OAJ01199.1 - 7.6e-06 25.9 0.5 2.1e-05 24.5 0.3 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 OAJ01199.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit adh_short PF00106.20 OAJ01200.1 - 4.2e-09 36.5 0.1 6.9e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ01200.1 - 5e-05 23.0 0.1 7.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DeoC PF01791.4 OAJ01201.1 - 2.6e-33 115.2 3.1 5e-33 114.3 2.2 1.4 1 1 0 1 1 1 1 DeoC/LacD family aldolase Eno-Rase_NADH_b PF12242.3 OAJ01201.1 - 0.26 11.1 3.3 0.38 10.5 0.9 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PMT PF02366.13 OAJ01202.1 - 1.9e-68 230.5 19.1 1.9e-68 230.5 13.2 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ01202.1 - 4.9e-28 97.9 0.2 8.2e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 MIR domain Sec23_trunk PF04811.10 OAJ01203.1 - 6.6e-15 55.1 0.2 7.6e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain SSF PF00474.12 OAJ01203.1 - 0.0017 17.0 0.6 0.002 16.8 0.4 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family UPF0121 PF03661.8 OAJ01204.1 - 3e-22 79.0 4.6 6.3e-22 77.9 3.2 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ribosomal_S4e PF00900.15 OAJ01205.1 - 1.9e-31 107.5 1.2 3e-31 106.9 0.2 1.9 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 OAJ01205.1 - 7.4e-20 70.5 3.6 1.3e-19 69.7 2.5 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 OAJ01205.1 - 0.00016 21.2 0.9 0.00049 19.7 0.6 1.9 1 0 0 1 1 1 1 KOW motif S4 PF01479.20 OAJ01205.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain CMAS PF02353.15 OAJ01207.1 - 9.9e-62 208.4 0.1 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 OAJ01207.1 - 6e-14 52.0 0.0 1.2e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ01207.1 - 3e-09 37.2 0.0 1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ01207.1 - 1.9e-07 31.3 0.0 3.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ01207.1 - 2.3e-07 30.8 0.0 5.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ01207.1 - 3.9e-07 30.6 0.0 7.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ01207.1 - 1.2e-05 25.6 0.0 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ01207.1 - 1.3e-05 24.8 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 OAJ01207.1 - 3.3e-05 23.2 0.0 8.1e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.14 OAJ01207.1 - 0.0011 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 OAJ01207.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAJ01207.1 - 0.0036 16.6 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAJ01207.1 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase zf-C2H2_4 PF13894.1 OAJ01208.1 - 0.13 12.6 0.4 0.13 12.6 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Pro_isomerase PF00160.16 OAJ01209.1 - 2e-46 158.0 0.4 2.7e-46 157.6 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EPL1 PF10513.4 OAJ01210.1 - 3.7e-20 72.7 0.1 3.7e-20 72.7 0.0 4.6 5 0 0 5 5 5 1 Enhancer of polycomb-like DUF500 PF04366.7 OAJ01211.1 - 2.3e-43 146.6 1.1 1.2e-41 141.1 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF500) Chitin_synth_1 PF01644.12 OAJ01212.1 - 5.3e-66 221.4 0.0 8.7e-66 220.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ01212.1 - 3.2e-26 90.8 0.0 5.6e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ01212.1 - 1.1e-24 86.7 0.5 1.2e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ01212.1 - 1.8e-11 44.1 6.2 4.2e-11 42.9 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ01212.1 - 3.2e-05 23.8 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 YhjQ PF06564.7 OAJ01212.1 - 0.16 11.2 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 YhjQ protein TPR_11 PF13414.1 OAJ01217.1 - 0.0026 17.3 14.1 0.85 9.3 1.0 5.7 3 2 1 4 4 4 4 TPR repeat TPR_12 PF13424.1 OAJ01217.1 - 0.0073 16.2 18.7 1 9.3 0.1 6.8 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ01217.1 - 0.031 13.8 6.7 17 5.2 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01217.1 - 0.097 12.6 10.6 28 4.9 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat PRTase_1 PF11202.3 OAJ01218.1 - 0.15 11.0 0.0 0.23 10.3 0.0 1.3 1 1 0 1 1 1 0 Phosphoribosyl transferase (PRTase) Translin PF01997.11 OAJ01219.1 - 6.8e-42 143.3 0.2 3.3e-30 105.1 0.0 2.4 2 1 0 2 2 2 2 Translin family Methyltransf_28 PF02636.12 OAJ01219.1 - 0.076 12.4 0.0 0.81 9.0 0.0 2.2 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HisKA PF00512.20 OAJ01219.1 - 0.19 11.7 1.3 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DAO PF01266.19 OAJ01222.1 - 3.1e-39 134.9 0.3 6.1e-39 133.9 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ01222.1 - 0.00038 20.4 0.1 0.0009 19.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 OAJ01222.1 - 0.0071 14.5 0.1 0.017 13.3 0.0 1.6 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 OAJ01222.1 - 0.04 12.8 0.1 0.14 11.0 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ01222.1 - 0.055 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ01222.1 - 0.072 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAJ01222.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain IL13 PF03487.8 OAJ01222.1 - 0.4 10.4 2.2 0.45 10.2 0.2 2.0 2 0 0 2 2 2 0 Interleukin-13 Collagen PF01391.13 OAJ01223.1 - 0.12 11.9 13.7 6 6.4 9.5 2.2 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) E1-E2_ATPase PF00122.15 OAJ01226.1 - 6.5e-63 211.8 4.1 2e-62 210.2 1.8 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ01226.1 - 1.4e-46 158.2 4.3 1.6e-45 154.8 1.5 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ01226.1 - 3e-30 106.2 0.0 9.6e-24 84.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ01226.1 - 3.5e-19 68.5 0.0 6.4e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ01226.1 - 6e-19 67.2 0.0 1.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ01226.1 - 2e-13 50.9 0.0 1.2e-12 48.3 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ01226.1 - 6.7e-06 25.8 1.2 0.00044 19.9 1.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ01226.1 - 0.01 16.0 0.0 0.038 14.1 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase adh_short PF00106.20 OAJ01227.1 - 1.7e-29 102.9 2.4 2.2e-29 102.4 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ01227.1 - 6.5e-26 91.5 0.5 1.8e-25 90.1 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ01227.1 - 2e-15 56.9 1.6 4.7e-15 55.7 1.1 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAJ01227.1 - 0.003 17.2 1.0 0.0067 16.0 0.7 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ01227.1 - 0.02 15.0 0.1 0.061 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ01227.1 - 0.021 14.0 0.1 0.035 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 OAJ01227.1 - 0.11 13.0 0.2 0.25 11.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain GDA1_CD39 PF01150.12 OAJ01228.1 - 6.2e-71 239.1 0.0 9.4e-59 199.0 0.0 3.1 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 OAJ01228.1 - 0.02 14.0 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family DUF605 PF04652.11 OAJ01229.1 - 3.5e-90 303.1 24.1 1.9e-89 300.7 16.7 2.0 1 1 0 1 1 1 1 Vta1 like BNIP2 PF12496.3 OAJ01230.1 - 0.03 14.5 2.9 0.051 13.7 0.1 2.2 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TPR_2 PF07719.12 OAJ01232.1 - 0.0035 17.1 1.6 57 3.9 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ01232.1 - 0.091 13.4 7.1 1.4 9.7 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01232.1 - 1.7 8.6 11.3 0.96 9.4 0.1 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ01233.1 - 0.0091 15.6 4.6 0.035 13.7 0.1 3.5 3 1 0 3 3 3 1 TPR repeat TPR_17 PF13431.1 OAJ01233.1 - 0.071 13.3 0.0 0.33 11.2 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ01233.1 - 0.22 12.2 0.1 0.22 12.2 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01234.1 - 1.6e-09 37.5 6.2 0.48 10.3 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01234.1 - 1.7e-05 24.3 4.7 4.8 7.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ01234.1 - 0.00026 20.5 1.4 2 8.1 0.1 4.1 3 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 OAJ01234.1 - 0.62 10.8 13.1 2.1 9.2 0.5 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat rve PF00665.21 OAJ01239.1 - 3.1e-16 59.5 0.0 8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ01239.1 - 2.2e-05 24.8 0.0 6.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ01239.1 - 3.1e-05 23.7 0.0 7.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ01239.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease rve_3 PF13683.1 OAJ01239.1 - 0.0055 16.2 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.5 OAJ01239.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Rad60-SLD PF11976.3 OAJ01239.1 - 0.047 13.3 0.0 21 4.9 0.0 3.3 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like zf-CCHC PF00098.18 OAJ01239.1 - 0.067 13.1 0.9 0.17 11.8 0.7 1.8 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2E PF12382.3 OAJ01239.1 - 0.22 11.3 0.0 0.49 10.1 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase CAF-1_p150 PF11600.3 OAJ01240.1 - 0.87 8.9 5.3 1.2 8.4 3.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cu_amine_oxid PF01179.15 OAJ01241.1 - 7e-112 374.1 0.1 8.9e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 OAJ01241.1 - 7.5e-26 89.8 0.4 1.9e-25 88.5 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 OAJ01241.1 - 1.8e-05 24.7 0.0 3.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pro_isomerase PF00160.16 OAJ01242.1 - 1.6e-45 155.1 0.2 1.8e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAP30_Sin3_bdg PF13867.1 OAJ01243.1 - 2.7e-07 30.3 0.0 3.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Nop14 PF04147.7 OAJ01243.1 - 0.46 8.3 1.6 0.66 7.8 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sas10 PF09368.5 OAJ01245.1 - 1.7e-24 85.7 3.1 1.7e-24 85.7 2.1 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 OAJ01245.1 - 5.9e-09 36.0 0.0 2.9e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 OAJ01246.1 - 2.6e-14 53.0 0.1 1.3e-13 50.7 0.0 2.1 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing Herpes_BLRF2 PF05812.7 OAJ01246.1 - 0.068 12.9 1.1 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein SEN1_N PF12726.2 OAJ01247.1 - 1.4e-67 228.4 0.4 5.8e-67 226.3 0.3 2.0 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 OAJ01247.1 - 7e-66 222.1 2.5 2.5e-65 220.3 1.8 2.0 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 OAJ01247.1 - 1.8e-60 203.7 0.0 1.8e-58 197.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ01247.1 - 1.5e-09 37.4 0.1 5.3e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ01247.1 - 4.9e-05 22.9 0.0 1.3 8.4 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 OAJ01247.1 - 0.00096 18.5 7.9 0.005 16.1 5.5 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 OAJ01247.1 - 0.0048 16.3 0.0 0.049 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Med9 PF07544.8 OAJ01247.1 - 0.018 14.7 4.5 0.058 13.1 3.1 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.1 OAJ01247.1 - 0.022 15.0 0.4 0.065 13.5 0.3 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 OAJ01247.1 - 0.032 14.0 3.7 1.6 8.5 2.6 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF342 PF03961.8 OAJ01247.1 - 0.042 12.2 2.5 0.068 11.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_22 PF13401.1 OAJ01247.1 - 0.057 13.5 1.0 0.54 10.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Nipped-B_C PF12830.2 OAJ01247.1 - 0.11 12.0 1.5 0.15 11.6 0.0 2.0 2 0 0 2 2 1 0 Sister chromatid cohesion C-terminus Atg14 PF10186.4 OAJ01247.1 - 0.57 9.0 7.2 13 4.6 6.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 OAJ01247.1 - 1.4 6.7 2.7 2.2 6.0 1.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 OAJ01247.1 - 1.6 8.9 6.6 4.9 7.3 2.5 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3573 PF12097.3 OAJ01247.1 - 4.8 5.6 3.0 8.1 4.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Yippee-Mis18 PF03226.9 OAJ01250.1 - 2.9e-12 46.4 0.0 9.2e-12 44.8 0.0 1.9 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.20 OAJ01252.1 - 1.8e-70 237.0 0.0 2.4e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01252.1 - 1.7e-29 102.7 0.0 2.6e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ01252.1 - 0.0027 17.4 6.3 0.03 14.0 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family MFS_1 PF07690.11 OAJ01253.1 - 2.1e-24 85.9 34.7 4e-16 58.6 8.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ01253.1 - 9.7e-15 54.0 4.9 9.7e-15 54.0 3.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Choline_transpo PF04515.7 OAJ01254.1 - 3.6e-86 288.9 20.8 3.6e-86 288.9 14.4 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter UPF0182 PF03699.8 OAJ01254.1 - 1.8 6.4 14.2 2.5 5.9 9.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) PAP2 PF01569.16 OAJ01254.1 - 8.8 6.0 24.5 0.24 11.0 0.2 4.5 2 1 3 5 5 5 0 PAP2 superfamily Ldh_1_N PF00056.18 OAJ01255.1 - 5.8e-44 149.3 0.1 8.8e-44 148.7 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 OAJ01255.1 - 3e-41 141.0 0.0 5.1e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 OAJ01255.1 - 0.00089 18.0 0.0 0.0023 16.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAJ01255.1 - 0.012 15.6 1.0 0.047 13.6 0.7 1.9 1 1 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 OAJ01255.1 - 0.016 15.4 0.3 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 OAJ01255.1 - 0.039 13.0 0.9 0.4 9.7 0.0 2.5 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LSM PF01423.17 OAJ01256.1 - 4.6e-16 58.1 0.0 6.7e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pribosyltran PF00156.22 OAJ01259.1 - 7.4e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HEAT PF02985.17 OAJ01260.1 - 3.2e-05 23.6 7.9 7.2 6.9 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat FAA_hydrolase_N PF09298.6 OAJ01260.1 - 0.1 12.5 0.2 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Fe-ADH PF00465.14 OAJ01262.1 - 1.6e-67 227.7 0.0 2.5e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 OAJ01262.1 - 6.4e-16 58.4 0.0 4.9e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 OAJ01262.1 - 0.009 14.9 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 1 3-dehydroquinate synthase cwf21 PF08312.7 OAJ01263.1 - 1.1e-16 60.4 4.4 1.1e-16 60.4 3.0 2.6 2 1 0 2 2 2 1 cwf21 domain EamA PF00892.15 OAJ01264.1 - 3.8e-11 43.1 25.6 7.5e-09 35.6 2.0 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 OAJ01264.1 - 4.6e-07 30.0 3.2 4.6e-07 30.0 2.2 2.8 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 OAJ01264.1 - 0.14 11.8 21.4 0.065 12.8 6.7 3.2 3 0 0 3 3 3 0 Triose-phosphate Transporter family UAA PF08449.6 OAJ01264.1 - 0.72 8.7 6.5 0.25 10.2 0.4 2.3 2 0 0 2 2 2 0 UAA transporter family O-antigen_lig PF13425.1 OAJ01265.1 - 0.0065 16.4 0.8 2 8.3 0.2 2.4 2 0 0 2 2 2 2 O-antigen ligase like membrane protein AdoMet_dc PF02675.10 OAJ01265.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase DUF4131 PF13567.1 OAJ01265.1 - 1.1 8.6 7.1 0.057 12.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UPF0182 PF03699.8 OAJ01266.1 - 0.0033 15.4 3.4 0.0033 15.4 2.3 1.5 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0182) Sec7_N PF12783.2 OAJ01266.1 - 0.11 11.9 1.5 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Plant_vir_prot PF01307.12 OAJ01266.1 - 0.18 11.5 1.7 0.28 10.9 0.0 2.3 2 2 1 3 3 3 0 Plant viral movement protein DUF2892 PF11127.3 OAJ01266.1 - 1 9.2 3.7 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) AMP-binding PF00501.23 OAJ01267.1 - 1.5e-79 267.4 0.0 1.8e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ01267.1 - 5.6e-12 46.4 0.0 1.1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 OAJ01267.1 - 0.14 10.6 0.0 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 GH3 auxin-responsive promoter RVT_1 PF00078.22 OAJ01270.1 - 2e-22 79.6 0.0 3.2e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pneumo_att_G PF05539.6 OAJ01270.1 - 0.31 10.3 13.1 0.48 9.7 9.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Methyltransf_11 PF08241.7 OAJ01271.1 - 2.8e-05 24.5 0.6 0.00042 20.7 0.2 2.7 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ01271.1 - 0.0034 17.7 0.0 0.022 15.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ01271.1 - 0.0048 16.4 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF3498 PF12004.3 OAJ01271.1 - 0.013 14.6 1.3 0.019 14.1 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Methyltransf_23 PF13489.1 OAJ01271.1 - 0.026 14.2 0.0 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3663 PF12404.3 OAJ01271.1 - 0.046 13.4 0.9 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 Peptidase Methyltransf_12 PF08242.7 OAJ01271.1 - 0.078 13.4 0.1 0.22 12.0 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ01271.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ01271.1 - 0.2 12.2 0.8 0.82 10.2 0.2 2.2 2 2 0 2 2 2 0 Methyltransferase domain Mt_ATP-synt_D PF05873.7 OAJ01272.1 - 8.5e-11 41.7 0.6 1.1e-10 41.4 0.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Cauli_AT PF03233.8 OAJ01272.1 - 0.016 14.9 0.8 0.025 14.3 0.6 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF1366 PF07104.6 OAJ01272.1 - 0.016 14.8 3.3 0.032 13.8 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) DUF4045 PF13254.1 OAJ01272.1 - 0.025 13.8 1.1 0.031 13.5 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2408 PF10303.4 OAJ01272.1 - 0.029 14.4 2.1 0.043 13.9 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) MiaE_2 PF13794.1 OAJ01272.1 - 0.051 13.0 0.1 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Peptidase_M17_N PF02789.12 OAJ01272.1 - 0.068 12.9 1.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Peptidase_M75 PF09375.5 OAJ01272.1 - 0.13 11.5 2.1 0.2 10.9 1.3 1.4 1 1 0 1 1 1 0 Imelysin T5orf172 PF10544.4 OAJ01272.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.6 1 1 0 1 1 1 0 T5orf172 domain Phage_GP20 PF06810.6 OAJ01272.1 - 0.15 11.5 4.1 0.18 11.2 0.4 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 IL3 PF02059.10 OAJ01272.1 - 0.31 11.0 2.1 1.4 8.9 0.1 2.1 1 1 1 2 2 2 0 Interleukin-3 TMPIT PF07851.8 OAJ01272.1 - 0.38 9.7 3.2 0.48 9.4 2.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 OAJ01272.1 - 0.89 7.3 3.8 3.8 5.2 2.6 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 OAJ01272.1 - 1 8.8 4.7 5.5 6.5 3.1 1.8 1 1 0 1 1 1 0 IncA protein MbeB_N PF04837.7 OAJ01272.1 - 1.5 8.9 6.5 0.17 12.0 0.6 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Seryl_tRNA_N PF02403.17 OAJ01272.1 - 2.6 8.1 7.2 5.9 6.9 4.7 1.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MDMPI_C PF07398.6 OAJ01273.1 - 0.032 14.8 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 MDMPI C-terminal domain SPT16 PF08644.6 OAJ01274.1 - 7e-52 175.3 0.1 1.8e-51 173.9 0.0 1.8 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 OAJ01274.1 - 7.4e-40 136.1 0.3 2e-39 134.7 0.2 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 OAJ01274.1 - 1.5e-22 80.2 0.0 3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 OAJ01274.1 - 7.5e-21 73.9 1.0 1.5e-20 72.9 0.0 2.1 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Atg8 PF02991.11 OAJ01275.1 - 3.9e-52 174.5 0.2 4.6e-52 174.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 OAJ01275.1 - 5.2e-07 29.7 0.0 6.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Cys_Met_Meta_PP PF01053.15 OAJ01277.1 - 5.2e-118 393.6 0.0 7.2e-118 393.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 OAJ01277.1 - 3.6e-16 58.9 2.8 1.5e-15 56.9 1.7 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ01277.1 - 2.5e-05 24.3 1.1 0.00017 21.7 0.0 2.8 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 OAJ01277.1 - 0.0083 15.3 0.1 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PIF1 PF05970.9 OAJ01280.1 - 4.6e-18 65.2 0.0 6.9e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01280.1 - 3.3e-09 36.6 0.0 3.3e-09 36.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF605 PF04652.11 OAJ01280.1 - 7.7e-05 22.2 22.6 0.00012 21.6 15.7 1.3 1 0 0 1 1 1 1 Vta1 like AAA_22 PF13401.1 OAJ01280.1 - 0.21 11.7 1.9 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0506 PF11703.3 OAJ01280.1 - 1 9.3 9.5 2.9 7.9 0.2 2.5 2 0 0 2 2 2 0 UPF0506 Hamartin PF04388.7 OAJ01280.1 - 5.4 5.5 31.0 2.1 6.9 19.9 1.6 2 0 0 2 2 2 0 Hamartin protein E1-E2_ATPase PF00122.15 OAJ01284.1 - 0.00018 20.6 0.5 0.0013 17.7 0.4 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 OAJ01284.1 - 0.0029 17.5 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Bac_globin PF01152.16 OAJ01286.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial-like globin Lactamase_B_4 PF13691.1 OAJ01287.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNase Z endonuclease MOFRL PF05161.8 OAJ01288.1 - 0.75 9.9 4.8 0.34 11.0 0.5 2.3 2 0 0 2 2 2 0 MOFRL family PIGA PF08288.7 OAJ01292.1 - 1.1e-41 141.0 0.1 2.3e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAJ01292.1 - 2.4e-26 92.1 0.0 4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ01292.1 - 1.6e-16 60.5 1.0 1.6e-16 60.5 0.7 2.0 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAJ01292.1 - 1e-13 51.7 0.3 2.3e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ01292.1 - 1.8e-12 47.5 0.1 4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ01292.1 - 4.1e-07 30.1 0.0 1.3e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAJ01292.1 - 9e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like GFA PF04828.9 OAJ01294.1 - 6.6e-12 45.2 1.7 9e-12 44.7 0.7 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.19 OAJ01294.1 - 0.05 13.5 1.3 8.8 6.3 0.0 2.3 2 0 0 2 2 2 0 B-box zinc finger zf-ribbon_3 PF13248.1 OAJ01294.1 - 0.093 11.9 4.3 0.25 10.5 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 OAJ01294.1 - 0.16 11.7 4.1 0.81 9.5 2.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.1 OAJ01294.1 - 0.24 11.1 5.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 OAJ01294.1 - 0.46 10.0 4.5 0.99 8.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Prok-TraM PF09228.5 OAJ01296.1 - 0.12 12.5 0.1 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM CMS1 PF14617.1 OAJ01296.1 - 0.12 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PEN-2 PF10251.4 OAJ01300.1 - 0.027 14.6 0.4 0.057 13.6 0.3 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase PSDC PF12588.3 OAJ01301.1 - 0.084 12.4 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Phophatidylserine decarboxylase Ish1 PF10281.4 OAJ01303.1 - 2.4e-24 85.0 9.4 1.8e-10 40.7 0.2 3.8 3 0 0 3 3 3 3 Putative stress-responsive nuclear envelope protein PIF1 PF05970.9 OAJ01303.1 - 6.2e-22 78.0 0.0 1.1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01303.1 - 4.6e-12 45.9 0.2 1.1e-10 41.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ01303.1 - 1.1e-07 31.7 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ01303.1 - 0.0013 18.7 0.9 0.0059 16.6 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Yip1 PF04893.12 OAJ01306.1 - 0.038 13.5 0.4 0.052 13.0 0.3 1.1 1 0 0 1 1 1 0 Yip1 domain Dynactin_p62 PF05502.8 OAJ01307.1 - 9.9e-69 232.3 6.9 9e-46 156.6 6.8 2.1 2 0 0 2 2 2 2 Dynactin p62 family zf-RING_2 PF13639.1 OAJ01309.1 - 8.1e-10 38.3 13.9 8e-05 22.3 1.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ01309.1 - 2.3e-08 33.9 18.3 2.8e-06 27.2 3.8 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ01309.1 - 1.1e-06 28.2 15.4 8e-06 25.4 2.7 2.8 2 0 0 2 2 2 2 zinc-RING finger domain Rtf2 PF04641.7 OAJ01309.1 - 2e-06 27.1 8.2 5e-05 22.6 1.2 3.2 2 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 OAJ01309.1 - 5.8e-05 22.6 19.5 0.0028 17.2 3.3 2.7 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 OAJ01309.1 - 0.001 18.9 5.7 0.001 18.9 3.9 2.9 2 2 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.1 OAJ01309.1 - 0.0088 15.8 4.8 0.0088 15.8 3.3 4.0 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-BED PF02892.10 OAJ01309.1 - 0.015 15.0 0.7 4.6 7.0 0.1 2.8 2 0 0 2 2 2 0 BED zinc finger zf-C3HC4 PF00097.20 OAJ01309.1 - 0.019 14.6 19.3 0.067 12.8 3.7 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 OAJ01309.1 - 0.11 12.4 2.9 5.9 6.9 0.1 3.0 2 0 0 2 2 2 0 Zinc ribbon domain Calici_PP_N PF08405.6 OAJ01309.1 - 0.13 11.0 0.3 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 Viral polyprotein N-terminal zf-RING_UBOX PF13445.1 OAJ01309.1 - 1.6 8.4 11.5 2.3 8.0 1.8 2.8 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ01309.1 - 4 7.2 11.4 0.25 11.1 0.6 2.7 2 1 1 3 3 3 0 zf-RING of BARD1-type protein Transformer PF06495.6 OAJ01309.1 - 4.8 7.0 9.3 9.1 6.1 6.5 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein Nnf1 PF03980.9 OAJ01310.1 - 0.0048 16.8 0.9 0.24 11.3 0.1 2.2 1 1 1 2 2 2 1 Nnf1 ABC_tran_2 PF12848.2 OAJ01310.1 - 0.039 13.7 0.7 0.062 13.1 0.5 1.4 1 0 0 1 1 1 0 ABC transporter CheZ PF04344.8 OAJ01310.1 - 0.057 13.0 2.2 0.077 12.6 1.1 1.5 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ BAR_2 PF10455.4 OAJ01310.1 - 0.068 12.0 0.8 0.081 11.8 0.6 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2536 PF10750.4 OAJ01310.1 - 0.1 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) DUF883 PF05957.8 OAJ01310.1 - 4.8 7.6 8.4 41 4.6 5.8 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GluR_Homer-bdg PF10606.4 OAJ01311.1 - 0.32 10.9 11.1 0.8 9.6 1.2 2.7 2 1 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor DcpS_C PF11969.3 OAJ01312.1 - 2e-21 76.3 0.1 3.2e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 OAJ01312.1 - 1.1e-09 38.7 1.6 3.1e-09 37.2 1.1 1.7 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.10 OAJ01312.1 - 0.036 13.7 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 zf-DHHC PF01529.15 OAJ01313.1 - 2.4e-39 134.4 0.1 4.7e-39 133.5 0.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase SR-25 PF10500.4 OAJ01313.1 - 0.0016 17.9 14.4 0.0034 16.8 10.0 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Histone PF00125.19 OAJ01314.1 - 5.2e-11 42.5 0.1 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ01314.1 - 0.00046 20.1 0.0 0.00098 19.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 OAJ01314.1 - 0.00093 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 OAJ01314.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S CENP-T PF15511.1 OAJ01314.1 - 0.036 13.3 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 OAJ01314.1 - 0.21 11.3 0.0 0.42 10.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit MOSC_N PF03476.11 OAJ01317.1 - 1.4e-17 63.5 0.0 3.4e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 OAJ01317.1 - 3e-06 26.7 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 MOSC domain zf-RING_2 PF13639.1 OAJ01318.1 - 1e-11 44.4 0.3 1e-11 44.4 0.2 2.7 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 OAJ01318.1 - 3.8e-10 39.7 1.2 8.7e-10 38.5 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 OAJ01318.1 - 1.6e-07 31.1 0.4 1.6e-07 31.1 0.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 OAJ01318.1 - 3.2e-07 30.2 6.4 6e-07 29.3 0.4 3.1 3 0 0 3 3 3 1 zinc-finger zf-C3HC4_3 PF13920.1 OAJ01318.1 - 6.2e-07 28.9 10.2 1.5e-06 27.7 2.6 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ01318.1 - 2.5e-05 23.8 1.4 2.5e-05 23.8 1.0 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ01318.1 - 4.6e-05 23.1 0.1 0.00013 21.7 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 OAJ01318.1 - 0.00011 21.8 1.1 0.00011 21.8 0.7 2.7 2 1 1 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.1 OAJ01318.1 - 0.011 15.3 0.4 0.011 15.3 0.3 1.7 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 OAJ01318.1 - 0.019 14.7 0.6 0.046 13.5 0.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 OAJ01318.1 - 0.029 14.3 2.6 0.51 10.3 1.8 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain DZR PF12773.2 OAJ01318.1 - 0.037 13.8 4.6 0.74 9.6 0.2 3.1 3 0 0 3 3 3 0 Double zinc ribbon HypA PF01155.14 OAJ01318.1 - 0.18 11.4 3.7 0.19 11.4 0.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_UBOX PF13445.1 OAJ01318.1 - 0.24 11.1 1.4 0.74 9.5 0.1 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Zn-ribbon_8 PF09723.5 OAJ01318.1 - 0.96 9.4 9.2 0.4 10.6 0.3 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-RING_4 PF14570.1 OAJ01318.1 - 1.2 8.7 8.7 0.5 9.9 0.1 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-TFIIB PF13453.1 OAJ01318.1 - 1.7 7.8 8.3 1.4 8.1 0.9 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger Nucleoplasmin PF03066.10 OAJ01319.1 - 0.44 10.0 7.4 0.11 12.0 0.5 2.5 2 0 0 2 2 2 0 Nucleoplasmin COG2 PF06148.6 OAJ01320.1 - 1.4e-13 50.8 0.4 5.4e-13 48.9 0.3 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 OAJ01320.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) DUF221 PF02714.10 OAJ01326.1 - 1.5e-83 280.4 17.5 2.2e-83 279.7 12.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ01326.1 - 8.9e-25 87.0 0.0 8.9e-25 87.0 0.0 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ01326.1 - 1.6e-09 38.1 0.5 5.1e-09 36.5 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) DUF204 PF02659.10 OAJ01326.1 - 2.1 8.5 6.4 13 6.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function DUF Tetraspannin PF00335.15 OAJ01327.1 - 6.6e-12 45.1 10.9 1.1e-11 44.4 7.5 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF2104 PF09877.4 OAJ01327.1 - 0.016 15.2 0.5 0.03 14.2 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) FA_desaturase PF00487.19 OAJ01327.1 - 0.029 13.8 2.2 0.055 12.9 1.5 1.4 1 0 0 1 1 1 0 Fatty acid desaturase TFIIA PF03153.8 OAJ01329.1 - 2.6 7.8 14.5 3.4 7.4 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCPVI PF02993.9 OAJ01329.1 - 6.6 6.8 17.0 3.4 7.7 8.9 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Pkinase PF00069.20 OAJ01330.1 - 3.8e-58 196.6 0.0 3.6e-57 193.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01330.1 - 1e-33 116.5 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01330.1 - 0.0006 18.8 0.0 0.00097 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3584 PF12128.3 OAJ01330.1 - 0.36 8.0 16.4 0.6 7.3 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ferric_reduct PF01794.14 OAJ01331.1 - 1.3 9.1 7.7 0.54 10.3 3.2 1.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component MaoC_dehydratas PF01575.14 OAJ01332.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain PNP_UDP_1 PF01048.15 OAJ01333.1 - 1.3e-33 115.9 0.5 1.5e-33 115.6 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily RVT_1 PF00078.22 OAJ01334.1 - 2.1e-15 56.6 0.0 3.5e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_2 PF07719.12 OAJ01335.1 - 0.00014 21.5 7.8 1.8 8.6 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ01335.1 - 0.00074 19.0 5.8 0.16 11.6 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ01335.1 - 0.003 18.0 5.6 2.8 8.8 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ01335.1 - 0.0096 16.5 12.2 0.33 11.6 0.2 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ01335.1 - 0.0097 15.5 8.3 0.096 12.3 0.0 4.1 4 2 1 5 5 5 2 TPR repeat TPR_19 PF14559.1 OAJ01335.1 - 0.034 14.4 14.8 7 7.0 0.0 6.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01335.1 - 0.062 13.2 14.7 1 9.3 0.2 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ01335.1 - 2.3 8.8 4.4 1e+02 3.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 OAJ01336.1 - 0.025 14.0 0.0 0.095 12.2 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase EF-hand_4 PF12763.2 OAJ01339.1 - 9.2e-35 118.5 0.0 3.9e-15 55.4 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 OAJ01339.1 - 5.9e-05 23.1 0.0 0.032 14.3 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain pair Macoilin PF09726.4 OAJ01339.1 - 0.019 13.2 11.9 0.031 12.5 8.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Reo_sigmaC PF04582.7 OAJ01339.1 - 0.48 9.5 8.8 1.3 8.0 0.6 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF342 PF03961.8 OAJ01339.1 - 1.3 7.3 6.6 2.1 6.6 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Synaptobrevin PF00957.16 OAJ01339.1 - 2.3 7.8 4.2 4 7.0 2.9 1.3 1 0 0 1 1 1 0 Synaptobrevin DUF972 PF06156.8 OAJ01339.1 - 3.4 8.0 11.1 2.9 8.3 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 OAJ01339.1 - 8.8 6.2 17.9 14 5.5 6.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PIGA PF08288.7 OAJ01340.1 - 1.1e-41 141.0 0.1 2.3e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 OAJ01340.1 - 7.8e-26 90.5 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ01340.1 - 6.1e-17 61.8 1.0 1.6e-16 60.4 0.7 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAJ01340.1 - 9.4e-14 51.8 0.3 2.4e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ01340.1 - 1.5e-11 44.6 0.0 3.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ01340.1 - 1.8e-05 24.9 0.0 5.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 OAJ01340.1 - 9.1e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like KNTase_C PF07827.6 OAJ01340.1 - 0.13 11.9 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 KNTase C-terminal domain NDK PF00334.14 OAJ01341.1 - 1.5e-49 167.2 0.0 2e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pyr_redox PF00070.22 OAJ01342.1 - 2.4e-12 47.0 0.4 1.8e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ01342.1 - 3.1e-11 43.5 0.2 6.5e-10 39.2 0.1 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ01342.1 - 3.8e-07 29.3 0.8 0.00017 20.6 0.1 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAJ01342.1 - 3.8e-06 27.1 0.2 0.0013 18.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ01342.1 - 1.2e-05 24.1 0.6 0.0002 20.1 0.0 2.5 2 1 1 3 3 3 1 Tryptophan halogenase DAO PF01266.19 OAJ01342.1 - 4.1e-05 22.6 2.6 0.0025 16.7 0.0 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.13 OAJ01342.1 - 6.6e-05 22.8 0.3 0.67 9.9 0.0 3.2 3 1 0 3 3 3 2 TrkA-N domain NAD_binding_7 PF13241.1 OAJ01342.1 - 0.00054 20.1 2.8 0.06 13.6 0.0 2.9 3 2 0 3 3 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 OAJ01342.1 - 0.0015 17.6 0.5 0.67 8.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 OAJ01342.1 - 0.0059 16.3 1.4 24 4.6 0.0 3.9 2 2 1 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 OAJ01342.1 - 0.017 13.6 2.0 3 6.2 0.1 3.3 2 1 2 4 4 4 0 HI0933-like protein Thi4 PF01946.12 OAJ01342.1 - 0.019 14.1 0.2 0.093 11.8 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 OAJ01342.1 - 0.025 14.5 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 OAJ01342.1 - 0.027 14.3 0.1 3.9 7.3 0.0 3.1 3 0 0 3 3 3 0 ThiF family Shikimate_DH PF01488.15 OAJ01342.1 - 0.033 14.2 0.3 4.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pribosyltran PF00156.22 OAJ01342.1 - 0.044 13.4 0.1 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosyl transferase domain GFO_IDH_MocA PF01408.17 OAJ01342.1 - 0.052 14.0 0.6 2.2 8.8 0.0 3.1 3 1 1 4 4 4 0 Oxidoreductase family, NAD-binding Rossmann fold Lycopene_cycl PF05834.7 OAJ01342.1 - 0.22 10.4 0.7 2 7.2 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein GATase_2 PF00310.16 OAJ01343.1 - 7e-25 87.4 0.1 1.5e-19 69.9 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ01343.1 - 1.4e-16 60.6 0.0 3.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 OAJ01343.1 - 4.2e-14 52.3 0.5 8.4e-14 51.3 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 OAJ01343.1 - 2.3e-12 46.7 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ01343.1 - 5.4e-07 28.5 0.0 8.2e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Histone PF00125.19 OAJ01344.1 - 6.9e-20 70.9 0.0 9.8e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ01344.1 - 7.9e-06 25.8 0.0 1.8e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Daxx PF03344.10 OAJ01345.1 - 0.046 12.2 8.1 0.062 11.7 5.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 OAJ01345.1 - 0.05 12.3 17.4 0.079 11.6 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EBV-NA3 PF05009.7 OAJ01345.1 - 1.3 8.1 5.1 2.4 7.3 3.5 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nop14 PF04147.7 OAJ01345.1 - 1.8 6.3 12.5 2.4 5.9 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ01345.1 - 2.5 7.2 12.0 3.5 6.8 8.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 OAJ01345.1 - 2.8 5.8 7.6 3.6 5.4 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 OAJ01345.1 - 4.4 5.5 7.2 6.2 5.0 5.0 1.1 1 0 0 1 1 1 0 Hsp90 protein Macoilin PF09726.4 OAJ01345.1 - 7 4.8 5.7 8.9 4.4 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Prefoldin_2 PF01920.15 OAJ01346.1 - 2.1e-20 72.4 1.6 2.9e-20 71.9 1.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF812 PF05667.6 OAJ01346.1 - 0.0067 15.0 3.4 0.0082 14.7 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF3166 PF11365.3 OAJ01346.1 - 0.021 15.2 1.6 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Prefoldin PF02996.12 OAJ01346.1 - 0.095 12.3 3.7 0.34 10.5 2.6 1.8 1 1 0 1 1 1 0 Prefoldin subunit TBPIP PF07106.8 OAJ01346.1 - 0.13 11.7 1.8 9.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tup_N PF08581.5 OAJ01346.1 - 0.22 11.7 2.8 0.44 10.7 0.4 2.1 2 0 0 2 2 2 0 Tup N-terminal DUF641 PF04859.7 OAJ01346.1 - 0.27 10.9 4.5 0.93 9.2 1.1 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DASH_Dad3 PF08656.5 OAJ01346.1 - 0.51 10.0 2.4 0.76 9.5 0.3 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 IFT57 PF10498.4 OAJ01346.1 - 0.64 8.7 3.6 6.4 5.4 0.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HrpB7 PF09486.5 OAJ01346.1 - 0.76 9.6 8.8 0.53 10.1 2.9 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) EzrA PF06160.7 OAJ01346.1 - 1.1 7.3 5.2 1.5 6.8 0.1 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF4407 PF14362.1 OAJ01346.1 - 1.3 7.9 5.6 2.6 6.9 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF964 PF06133.6 OAJ01346.1 - 1.4 8.9 7.7 4 7.4 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF964) bZIP_Maf PF03131.12 OAJ01346.1 - 1.6 9.0 5.5 8.5 6.7 1.5 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor TPR_MLP1_2 PF07926.7 OAJ01346.1 - 2.9 7.6 8.5 5.3 6.7 3.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 OAJ01346.1 - 7.2 6.1 8.3 20 4.6 5.7 1.7 1 1 0 1 1 1 0 IncA protein HA2 PF04408.18 OAJ01347.1 - 6.9e-20 70.9 0.0 1.4e-18 66.8 0.0 2.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ01347.1 - 8.5e-14 51.1 0.0 5.2e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ01347.1 - 4.7e-12 45.7 0.0 1.4e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ01347.1 - 4.2e-07 29.6 0.0 9.8e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.1 OAJ01347.1 - 3.8e-05 24.1 1.8 0.028 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ01347.1 - 0.0018 18.4 0.0 0.0055 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ01347.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 OAJ01347.1 - 0.048 13.4 0.0 2.7 7.8 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ01347.1 - 0.11 12.2 2.5 0.18 11.6 0.1 2.6 3 0 0 3 3 3 0 Part of AAA domain BolA PF01722.13 OAJ01348.1 - 3.6e-16 58.8 0.0 5e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein GTP_cyclohydroI PF01227.17 OAJ01349.1 - 2.9e-75 251.4 0.3 6.6e-75 250.3 0.0 1.7 2 0 0 2 2 2 1 GTP cyclohydrolase I QueF PF14489.1 OAJ01349.1 - 0.0011 18.9 0.0 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 OAJ01349.1 - 0.015 15.0 0.2 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain CytochromB561_N PF09786.4 OAJ01349.1 - 0.31 9.4 10.3 0.45 8.9 7.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Abhydrolase_6 PF12697.2 OAJ01350.1 - 2e-23 83.4 0.1 3.1e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ01350.1 - 1.3e-14 54.3 0.4 5.6e-10 39.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ01350.1 - 2.7e-07 30.4 0.0 5.7e-07 29.3 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ01350.1 - 0.0012 18.3 0.0 0.0037 16.7 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 OAJ01350.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 OAJ01350.1 - 0.0036 15.8 0.0 0.0047 15.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 OAJ01350.1 - 0.0082 15.3 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAJ01350.1 - 0.038 13.4 0.0 0.71 9.2 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Lipase_GDSL PF00657.17 OAJ01354.1 - 5.8e-15 55.7 0.0 7.4e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 OAJ01354.1 - 5.3e-07 29.9 0.1 7.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Fip1 PF05182.8 OAJ01355.1 - 1.1e-19 69.3 0.9 1.9e-19 68.6 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif DUF1777 PF08648.7 OAJ01355.1 - 0.0022 17.7 4.4 0.0022 17.7 3.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1777) COPI_C PF06957.6 OAJ01355.1 - 0.069 11.6 7.4 0.17 10.3 5.1 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus IMS PF00817.15 OAJ01357.1 - 6e-37 126.7 0.1 1.7e-36 125.2 0.1 1.8 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ01357.1 - 0.00038 20.3 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain TPT PF03151.11 OAJ01358.1 - 5.1e-20 71.6 11.4 5.1e-20 71.6 7.9 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ01358.1 - 1.7e-05 24.8 28.9 1.9e-05 24.6 5.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family FAT PF02259.18 OAJ01359.1 - 9.5e-113 376.7 5.6 1.1e-112 376.5 2.4 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ01359.1 - 9.5e-53 179.0 0.3 1.6e-52 178.3 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 OAJ01359.1 - 4.2e-46 156.8 0.0 6.2e-44 149.7 0.0 3.4 3 0 0 3 3 2 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 OAJ01359.1 - 8.4e-38 128.4 2.3 2.1e-37 127.2 0.4 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 OAJ01359.1 - 2.7e-18 66.0 19.1 0.0013 18.9 0.0 9.9 7 3 2 9 9 9 4 HEAT repeats HEAT PF02985.17 OAJ01359.1 - 3.4e-14 51.5 14.9 0.32 11.1 0.0 11.0 11 0 0 11 11 11 5 HEAT repeat FATC PF02260.15 OAJ01359.1 - 1.8e-10 40.0 0.2 4.4e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.2 OAJ01359.1 - 4.3e-06 26.7 2.2 0.012 15.5 0.0 6.1 6 1 2 8 8 8 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ01359.1 - 0.00035 20.9 40.1 0.024 15.1 0.1 11.6 14 2 1 15 15 13 3 HEAT-like repeat Adaptin_N PF01602.15 OAJ01359.1 - 0.00052 18.4 4.1 0.0048 15.2 0.2 3.9 4 1 0 4 4 4 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 OAJ01359.1 - 0.0032 15.8 0.2 0.04 12.1 0.1 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit UME PF08064.8 OAJ01359.1 - 0.0035 17.2 0.2 5.3 7.0 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain IBN_N PF03810.14 OAJ01359.1 - 0.021 14.7 0.1 2.3 8.2 0.0 4.2 5 0 0 5 5 4 0 Importin-beta N-terminal domain FdhE PF04216.7 OAJ01359.1 - 0.68 9.5 7.2 0.49 10.0 0.2 3.7 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation AT_hook PF02178.14 OAJ01360.1 - 1 9.2 8.0 3.6 7.5 5.5 2.0 1 0 0 1 1 1 0 AT hook motif Paramyxo_PNT PF13825.1 OAJ01361.1 - 0.63 9.1 5.4 0.19 10.8 1.8 1.5 1 1 1 2 2 2 0 Paramyxovirus structural protein V/P N-terminus RFX5_DNA_bdg PF14621.1 OAJ01362.1 - 0.021 14.4 2.4 0.026 14.1 1.7 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain AT_hook PF02178.14 OAJ01362.1 - 0.11 12.2 4.4 0.29 10.9 3.1 1.8 1 0 0 1 1 1 0 AT hook motif AAA_18 PF13238.1 OAJ01363.1 - 3.3e-07 30.6 0.1 3.9e-06 27.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAJ01363.1 - 2.8e-05 23.7 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 OAJ01363.1 - 0.0029 18.4 0.1 0.0066 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ01363.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B HSP70 PF00012.15 OAJ01364.1 - 1e-45 155.8 0.5 1.1e-45 155.6 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein ABC_membrane PF00664.18 OAJ01366.1 - 6.8e-67 225.7 22.7 5.9e-38 130.8 3.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ01366.1 - 8.7e-61 204.2 0.0 2.6e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ01366.1 - 6.9e-10 39.3 0.2 0.013 15.5 0.0 3.7 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 OAJ01366.1 - 1.4e-09 37.5 5.6 0.00069 18.9 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 OAJ01366.1 - 7.4e-08 33.2 0.0 0.0046 17.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ01366.1 - 1.6e-07 30.7 2.7 0.0061 16.0 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ01366.1 - 4.8e-07 29.3 0.3 0.1 11.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 OAJ01366.1 - 2.7e-06 26.6 0.1 0.0029 16.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 OAJ01366.1 - 2.8e-06 27.6 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ01366.1 - 1.7e-05 24.9 1.3 0.015 15.4 0.1 3.7 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 OAJ01366.1 - 4.6e-05 23.4 11.6 0.00041 20.3 1.2 3.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 OAJ01366.1 - 5.6e-05 22.7 6.5 3.3 7.0 0.2 5.2 5 0 0 5 5 5 1 AAA-like domain IstB_IS21 PF01695.12 OAJ01366.1 - 7.5e-05 22.2 0.1 1.9 7.9 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_ATPase PF09818.4 OAJ01366.1 - 0.00037 19.1 0.2 0.045 12.3 0.0 3.5 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_28 PF13521.1 OAJ01366.1 - 0.0019 18.2 1.2 0.17 11.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 OAJ01366.1 - 0.0037 17.1 0.2 1 9.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 OAJ01366.1 - 0.0043 16.2 0.4 2.6 7.0 0.2 2.7 2 0 0 2 2 2 1 KaiC ATP-synt_ab PF00006.20 OAJ01366.1 - 0.005 16.3 0.1 2.3 7.6 0.1 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 OAJ01366.1 - 0.0065 16.2 0.8 3.7 7.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 OAJ01366.1 - 0.016 14.3 0.7 0.94 8.5 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 OAJ01366.1 - 0.018 14.5 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 OAJ01366.1 - 0.019 14.6 0.9 0.72 9.4 0.0 3.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 OAJ01366.1 - 0.022 14.8 0.2 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 OAJ01366.1 - 0.041 13.5 0.2 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 OAJ01366.1 - 0.045 13.2 0.2 7 6.0 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 OAJ01366.1 - 0.045 14.2 0.2 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Mg_chelatase PF01078.16 OAJ01366.1 - 0.051 12.7 0.0 3.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAJ01366.1 - 0.058 13.3 0.0 5.2 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 OAJ01366.1 - 0.058 13.0 0.3 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 OAJ01366.1 - 0.082 12.7 5.3 0.65 9.7 0.2 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 OAJ01366.1 - 0.12 12.3 0.9 3.4 7.6 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase PRK PF00485.13 OAJ01366.1 - 0.12 11.8 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.15 OAJ01366.1 - 0.14 10.7 0.2 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_23 PF13476.1 OAJ01366.1 - 0.22 11.8 3.9 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAJ01366.1 - 0.23 10.2 0.8 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_13 PF13166.1 OAJ01366.1 - 0.57 8.5 0.1 17 3.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU_D2 PF03144.20 OAJ01367.1 - 0.00043 20.3 1.1 0.0078 16.3 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu domain 2 HSP70 PF00012.15 OAJ01367.1 - 0.0014 16.6 0.1 0.0015 16.5 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein zf-met2 PF12907.2 OAJ01368.1 - 8.8e-13 47.9 3.4 1.3e-12 47.4 2.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 OAJ01368.1 - 1.4e-08 35.3 13.2 1.4e-08 35.3 9.2 1.5 2 0 0 2 2 2 1 4F5 protein family Ribosomal_S15 PF00312.17 OAJ01368.1 - 0.017 14.8 0.1 0.032 13.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S15 zinc_ribbon_4 PF13717.1 OAJ01368.1 - 0.061 13.0 0.2 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Eapp_C PF10238.4 OAJ01368.1 - 0.064 13.1 4.1 0.067 13.0 2.6 1.2 1 1 0 1 1 1 0 E2F-associated phosphoprotein zinc_ribbon_5 PF13719.1 OAJ01368.1 - 0.068 12.7 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain V-ATPase_G PF03179.10 OAJ01368.1 - 1.9 8.8 6.0 2.6 8.3 4.2 1.2 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit FAT PF02259.18 OAJ01369.1 - 3.8e-111 371.4 2.5 9e-111 370.2 1.8 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ01369.1 - 2.5e-51 174.4 0.4 4.5e-51 173.6 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 OAJ01369.1 - 2.3e-47 160.8 0.0 4.6e-44 150.1 0.0 3.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 OAJ01369.1 - 2.2e-27 95.0 0.1 1.3e-26 92.5 0.1 2.5 1 0 0 1 1 1 1 Rapamycin binding domain HEAT_2 PF13646.1 OAJ01369.1 - 6.7e-17 61.5 20.7 0.00066 19.9 0.1 10.8 6 3 6 12 12 12 4 HEAT repeats HEAT PF02985.17 OAJ01369.1 - 7e-10 38.1 26.2 0.079 13.0 0.0 13.3 13 1 0 13 13 13 3 HEAT repeat FATC PF02260.15 OAJ01369.1 - 4.1e-09 35.7 0.1 9.5e-09 34.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.1 OAJ01369.1 - 2.7e-06 27.6 46.5 0.19 12.2 0.2 14.1 13 3 4 17 17 15 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ01369.1 - 1.5e-05 25.2 0.0 20 5.6 0.0 6.7 5 2 2 7 7 7 0 Vacuolar 14 Fab1-binding region UME PF08064.8 OAJ01369.1 - 4.6e-05 23.3 0.1 9.4 6.2 0.0 6.0 4 1 1 5 5 5 1 UME (NUC010) domain Cnd1 PF12717.2 OAJ01369.1 - 6.5e-05 22.8 0.2 0.073 12.9 0.1 4.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 OAJ01369.1 - 0.032 13.8 0.0 3.1 7.4 0.0 3.7 3 1 1 4 4 4 0 VHS domain Herpes_BBRF1 PF04793.7 OAJ01369.1 - 0.058 12.1 0.2 0.69 8.6 0.0 2.4 2 0 0 2 2 2 0 BRRF1-like protein RIX1 PF08167.7 OAJ01369.1 - 0.11 12.1 2.6 6.2 6.4 0.0 4.6 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis RNase_P_Rpp14 PF01900.14 OAJ01370.1 - 3.3e-25 88.0 0.0 4.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family NT-C2 PF10358.4 OAJ01371.1 - 1.1e-10 41.2 0.0 0.0013 18.2 0.0 3.6 3 1 0 3 3 3 3 N-terminal C2 in EEIG1 and EHBP1 proteins RNase_PH PF01138.16 OAJ01372.1 - 1.3e-06 28.7 0.3 2.3e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AAA_18 PF13238.1 OAJ01373.1 - 1e-07 32.3 0.1 9.9e-07 29.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 OAJ01373.1 - 2.9e-06 26.9 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 OAJ01373.1 - 0.0042 17.8 0.1 0.0087 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ01373.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 OAJ01373.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF996 PF06195.8 OAJ01379.1 - 0.57 10.1 0.0 0.57 10.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF996) ABC_tran PF00005.22 OAJ01381.1 - 3.6e-09 37.0 0.0 8.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ01381.1 - 1.6e-06 28.2 0.0 2.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAJ01381.1 - 0.00046 19.3 0.0 0.00063 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 OAJ01381.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ribosomal_L2_C PF03947.13 OAJ01382.1 - 3e-40 137.0 1.0 5.3e-40 136.2 0.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 OAJ01382.1 - 1.1e-13 50.8 0.1 2.1e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF922 PF06037.6 OAJ01383.1 - 0.05 12.9 1.1 0.11 11.8 0.7 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) FAD_binding_1 PF00667.15 OAJ01384.1 - 0.0097 15.3 0.2 0.012 15.0 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain ATAD4 PF15321.1 OAJ01384.1 - 0.12 13.3 9.1 0.32 12.0 6.3 1.7 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 Sec6 PF06046.8 OAJ01384.1 - 0.17 9.9 1.5 0.21 9.6 1.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 IncA PF04156.9 OAJ01384.1 - 4.5 6.8 7.3 5.5 6.5 5.0 1.1 1 0 0 1 1 1 0 IncA protein PPP4R2 PF09184.6 OAJ01385.1 - 2.7e-11 43.5 0.0 2.7e-11 43.5 0.0 3.5 4 0 0 4 4 4 1 PPP4R2 Pal1 PF08316.6 OAJ01386.1 - 4.9e-16 59.4 1.1 4.9e-16 59.4 0.8 2.1 1 1 1 2 2 2 1 Pal1 cell morphology protein BRE1 PF08647.6 OAJ01389.1 - 0.07 13.1 6.1 0.052 13.5 2.5 2.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.10 OAJ01389.1 - 0.13 11.7 3.8 0.27 10.7 1.6 2.1 2 0 0 2 2 2 0 Septum formation initiator Rab5-bind PF09311.6 OAJ01389.1 - 0.57 10.0 9.5 0.75 9.6 5.4 1.9 2 0 0 2 2 2 0 Rabaptin-like protein Protoglobin PF11563.3 OAJ01390.1 - 0.095 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protoglobin CS PF04969.11 OAJ01391.1 - 1.3e-19 70.5 0.2 2.2e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 CS domain DASH_Dad1 PF08649.5 OAJ01392.1 - 4.2e-20 71.1 0.2 5.4e-20 70.8 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 EAP30 PF04157.11 OAJ01393.1 - 8.4e-30 103.5 0.2 1.7e-29 102.5 0.1 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 OAJ01393.1 - 5.3e-23 80.6 0.0 9.2e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Rubredoxin PF00301.15 OAJ01393.1 - 0.0029 17.4 0.7 0.033 14.0 0.0 2.8 3 0 0 3 3 3 1 Rubredoxin DZR PF12773.2 OAJ01393.1 - 0.004 16.9 5.6 0.11 12.2 0.4 2.3 2 0 0 2 2 2 2 Double zinc ribbon GRAM PF02893.15 OAJ01393.1 - 0.029 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.13 OAJ01393.1 - 0.062 12.4 12.5 0.69 9.0 1.3 2.7 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 OAJ01393.1 - 7.4 6.2 11.4 1.7 8.2 0.4 2.7 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger CLU PF13236.1 OAJ01394.1 - 6.3e-67 225.2 0.0 7.7e-66 221.6 0.0 2.2 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 OAJ01394.1 - 2.2e-42 144.8 0.0 8.4e-42 142.9 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 OAJ01394.1 - 3.4e-17 62.1 4.7 1.3e-08 34.6 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ01394.1 - 2.1e-07 30.6 6.4 0.012 15.4 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat CLU_N PF15044.1 OAJ01394.1 - 3e-05 24.0 0.0 0.00028 20.9 0.0 2.6 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_11 PF13414.1 OAJ01394.1 - 0.00027 20.5 0.4 0.0025 17.4 0.1 2.7 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 OAJ01394.1 - 0.026 14.1 0.1 0.5 10.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ01394.1 - 0.089 12.6 0.8 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PINIT PF14324.1 OAJ01395.1 - 1.2e-24 87.0 0.4 1.2e-24 87.0 0.3 1.5 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 OAJ01395.1 - 7.4e-21 73.4 4.0 1.2e-20 72.6 2.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 OAJ01395.1 - 9e-08 31.5 0.9 1.7e-07 30.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 OAJ01395.1 - 0.0044 16.5 0.0 0.0098 15.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain Frag1 PF10277.4 OAJ01398.1 - 6.7e-36 123.7 16.9 7.8e-36 123.5 11.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Yip1 PF04893.12 OAJ01398.1 - 0.00034 20.1 8.1 0.00049 19.6 1.5 2.3 1 1 1 2 2 2 1 Yip1 domain zf-DHHC PF01529.15 OAJ01398.1 - 0.32 10.3 10.1 0.11 11.8 0.3 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4519 PF15012.1 OAJ01398.1 - 2.3 8.2 5.0 2.5 8.0 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4149 PF13664.1 OAJ01398.1 - 7.5 6.6 9.9 10 6.2 3.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) EXS PF03124.9 OAJ01399.1 - 9.4e-59 199.1 6.4 2.9e-52 177.8 4.6 2.2 2 0 0 2 2 2 2 EXS family Vma12 PF11712.3 OAJ01399.1 - 0.3 10.8 1.3 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box-like PF12937.2 OAJ01404.1 - 2.7e-05 23.7 0.6 6.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 OAJ01405.1 - 3.9e-06 26.2 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01405.1 - 0.00014 21.0 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LSM PF01423.17 OAJ01408.1 - 2e-09 36.8 0.0 3.6e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 LSM domain Glyco_transf_20 PF00982.16 OAJ01409.1 - 2.2e-186 619.9 0.0 2.4e-137 458.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 OAJ01409.1 - 0.05 13.0 0.1 5.9 6.2 0.0 2.6 2 1 0 2 2 2 0 Glycosyl transferases group 1 SpoIIIAH PF12685.2 OAJ01410.1 - 0.012 15.0 0.5 0.021 14.3 0.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Sedlin_N PF04628.8 OAJ01412.1 - 1.8e-37 128.1 0.0 3.5e-37 127.1 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 OAJ01412.1 - 5e-06 26.2 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Evr1_Alr PF04777.8 OAJ01413.1 - 3.3e-29 100.6 0.3 4.8e-29 100.1 0.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family RNA_pol_Rpb1_1 PF04997.7 OAJ01414.1 - 2.6e-113 378.7 0.0 3.6e-113 378.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 OAJ01414.1 - 9.8e-104 346.4 0.1 1.4e-103 345.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 OAJ01414.1 - 3.3e-68 228.8 0.0 6.7e-68 227.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 OAJ01414.1 - 2.1e-60 203.6 0.2 3.7e-60 202.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 OAJ01414.1 - 3.5e-45 153.5 0.0 7.2e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 OAJ01414.1 - 1.7e-42 144.3 1.0 3.6e-42 143.2 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 OAJ01414.1 - 2.9e-36 123.5 0.0 7.1e-36 122.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 OAJ01414.1 - 9.2e-18 62.7 258.5 0.023 14.7 6.8 17.1 12 2 5 19 19 19 15 RNA polymerase Rpb1 C-terminal repeat PCI PF01399.22 OAJ01415.1 - 6.9e-20 71.3 0.0 2.1e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain HTH_27 PF13463.1 OAJ01415.1 - 0.0031 17.8 0.0 0.0092 16.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix DNA-binding domain TPR_20 PF14561.1 OAJ01415.1 - 0.1 12.7 3.8 0.54 10.3 1.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FA_hydroxylase PF04116.8 OAJ01417.1 - 4.6e-14 52.7 4.0 4.6e-14 52.7 2.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NmrA PF05368.8 OAJ01419.1 - 5.4e-14 51.9 0.0 6.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ01419.1 - 7.1e-10 39.1 0.0 1.3e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 OAJ01419.1 - 0.033 13.1 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HARP PF07443.8 OAJ01419.1 - 0.15 11.4 0.2 0.5 9.7 0.1 1.8 2 0 0 2 2 2 0 HepA-related protein (HARP) Fungal_trans PF04082.13 OAJ01420.1 - 1e-15 57.3 0.0 2.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ01420.1 - 1.5e-08 34.3 9.6 2.8e-08 33.5 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC8 PF04049.8 OAJ01421.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 RrnaAD PF00398.15 OAJ01423.1 - 3e-22 78.9 0.0 4.3e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Hep_59 PF07052.6 OAJ01424.1 - 1.5e-27 95.9 0.8 1.5e-27 95.9 0.6 3.0 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 GspL_C PF12693.2 OAJ01424.1 - 0.11 12.2 1.2 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 GspL periplasmic domain ABC_tran PF00005.22 OAJ01425.1 - 1.4e-35 122.6 0.1 1.2e-17 64.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 OAJ01425.1 - 2.7e-14 52.4 5.4 6.9e-14 51.1 3.8 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 OAJ01425.1 - 3.9e-14 53.2 3.0 0.0054 16.7 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 OAJ01425.1 - 4.9e-10 39.0 5.1 0.0017 17.6 0.5 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 OAJ01425.1 - 2.2e-07 30.1 3.3 2.2e-07 30.1 2.3 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain DUF258 PF03193.11 OAJ01425.1 - 5.6e-06 25.6 1.1 0.1 11.8 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ01425.1 - 7.4e-06 26.1 0.2 0.005 16.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 OAJ01425.1 - 8.5e-06 25.0 0.3 4.2 6.3 0.0 4.7 5 0 0 5 5 5 0 AAA ATPase domain AAA PF00004.24 OAJ01425.1 - 1.1e-05 25.6 0.0 0.044 13.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAJ01425.1 - 1.5e-05 24.3 0.2 0.039 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 OAJ01425.1 - 7.9e-05 22.3 11.1 8.2e-05 22.3 1.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 OAJ01425.1 - 0.00018 21.8 9.4 0.00054 20.2 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Miro PF08477.8 OAJ01425.1 - 0.00021 21.8 0.5 0.35 11.3 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein NACHT PF05729.7 OAJ01425.1 - 0.00035 20.2 1.1 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 OAJ01425.1 - 0.00039 19.8 0.1 0.34 10.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain VirE PF05272.6 OAJ01425.1 - 0.00041 19.8 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 2 Virulence-associated protein E AAA_23 PF13476.1 OAJ01425.1 - 0.00092 19.5 2.7 0.062 13.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ01425.1 - 0.0011 18.8 0.0 1.5 8.7 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 OAJ01425.1 - 0.0015 18.7 0.3 0.46 10.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 OAJ01425.1 - 0.0017 18.4 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 OAJ01425.1 - 0.0017 18.1 13.8 0.0041 16.9 9.6 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_17 PF13207.1 OAJ01425.1 - 0.0019 19.0 1.5 1.1 10.0 0.2 2.9 2 2 0 2 2 2 1 AAA domain Fer4_2 PF12797.2 OAJ01425.1 - 0.0027 17.5 2.8 0.0027 17.5 2.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.1 OAJ01425.1 - 0.0034 17.2 0.7 0.45 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 OAJ01425.1 - 0.0043 16.7 0.5 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 OAJ01425.1 - 0.0045 16.6 0.2 0.068 12.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_10 PF13237.1 OAJ01425.1 - 0.0052 16.5 1.9 0.0052 16.5 1.3 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAJ01425.1 - 0.0091 16.7 0.2 0.0091 16.7 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 OAJ01425.1 - 0.011 15.9 2.3 0.011 15.9 1.6 2.1 1 1 2 3 3 3 0 4Fe-4S dicluster domain NB-ARC PF00931.17 OAJ01425.1 - 0.014 14.2 0.0 0.47 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.17 OAJ01425.1 - 0.015 14.7 2.7 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.1 OAJ01425.1 - 0.02 15.1 0.2 2 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ01425.1 - 0.027 14.4 0.9 5.4 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 OAJ01425.1 - 0.03 14.3 1.6 0.03 14.3 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Rad17 PF03215.10 OAJ01425.1 - 0.032 12.9 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 OAJ01425.1 - 0.057 12.9 0.1 2.5 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 OAJ01425.1 - 0.063 12.6 0.0 9.1 5.6 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Sigma54_activ_2 PF14532.1 OAJ01425.1 - 0.094 12.7 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ01425.1 - 0.17 11.5 0.7 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 OAJ01425.1 - 0.21 10.9 2.3 7 5.9 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain Fer4_4 PF12800.2 OAJ01425.1 - 0.39 11.1 13.2 0.071 13.4 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 OAJ01425.1 - 5.6 7.3 11.9 0.13 12.6 0.8 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_3 PF12798.2 OAJ01425.1 - 5.7 7.7 13.5 0.11 13.0 2.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Podoplanin PF05808.6 OAJ01428.1 - 0.00011 21.8 8.7 0.00021 20.8 6.1 1.4 1 0 0 1 1 1 1 Podoplanin Mucin PF01456.12 OAJ01428.1 - 0.0092 15.7 36.3 0.022 14.5 25.1 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein Adeno_E3_CR2 PF02439.10 OAJ01428.1 - 0.019 14.5 0.5 0.032 13.7 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PMP1_2 PF08114.6 OAJ01428.1 - 0.037 13.5 0.2 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 ATPase proteolipid family DLH PF01738.13 OAJ01429.1 - 1.4e-11 44.1 0.8 2.2e-11 43.4 0.6 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 OAJ01429.1 - 0.0092 15.7 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Daxx PF03344.10 OAJ01430.1 - 0.071 11.5 13.8 0.085 11.3 9.5 1.0 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 OAJ01430.1 - 0.43 9.4 16.4 0.54 9.1 11.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PROL5-SMR PF15621.1 OAJ01433.1 - 0.0036 17.7 1.2 0.01 16.2 0.8 1.7 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family Herpes_LAMP2 PF06126.6 OAJ01433.1 - 1.1 7.5 3.5 1.6 7.0 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 MULE PF10551.4 OAJ01434.1 - 1.2e-07 31.8 0.5 1.1e-06 28.6 0.1 2.5 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.12 OAJ01434.1 - 0.02 14.3 0.3 0.044 13.2 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger Cpn60_TCP1 PF00118.19 OAJ01435.1 - 4.4e-152 507.1 0.0 8.2e-152 506.2 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1572 PF07609.6 OAJ01435.1 - 0.13 11.7 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Plus-3 PF03126.13 OAJ01436.1 - 8.7e-07 28.9 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain NAD_binding_6 PF08030.7 OAJ01436.1 - 0.15 11.9 0.9 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Bravo_FIGEY PF13882.1 OAJ01437.1 - 0.017 16.0 0.1 0.064 14.1 0.0 1.8 2 0 0 2 2 2 0 Bravo-like intracellular region GTP_EFTU PF00009.22 OAJ01439.1 - 1.6e-60 203.7 0.3 2.7e-60 203.0 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ01439.1 - 4.8e-37 126.1 0.0 1.1e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ01439.1 - 2.9e-21 75.1 0.0 7e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ01439.1 - 2.1e-13 49.9 0.0 5.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ01439.1 - 4e-12 46.0 0.0 1.3e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ01439.1 - 7.5e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase CLASP_N PF12348.3 OAJ01440.1 - 5.1e-18 65.2 0.0 2.2e-05 23.9 0.0 5.2 5 0 0 5 5 5 3 CLASP N terminal HEAT PF02985.17 OAJ01440.1 - 2.3e-14 52.0 18.0 0.0017 18.2 0.1 10.4 13 0 0 13 13 10 3 HEAT repeat HEAT_2 PF13646.1 OAJ01440.1 - 3.5e-14 52.8 8.6 0.033 14.4 0.0 8.6 6 2 2 8 8 8 4 HEAT repeats Proteasom_PSMB PF10508.4 OAJ01440.1 - 0.00044 18.6 0.0 1.3 7.1 0.0 3.3 4 0 0 4 4 4 2 Proteasome non-ATPase 26S subunit Cohesin_HEAT PF12765.2 OAJ01440.1 - 0.00077 19.3 0.3 6.4 6.8 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.2 OAJ01440.1 - 0.0039 17.5 0.0 50 4.3 0.0 5.1 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 OAJ01440.1 - 0.0057 16.5 0.0 1 9.2 0.0 4.3 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 OAJ01440.1 - 0.011 16.2 18.9 1.6 9.3 0.0 8.0 8 1 1 9 9 8 0 HEAT-like repeat DUF2435 PF10363.4 OAJ01440.1 - 0.012 15.5 0.1 5.9 6.8 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) TAN PF11640.3 OAJ01440.1 - 0.013 15.2 1.0 4.5 7.0 0.0 3.7 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair Arm PF00514.18 OAJ01440.1 - 0.58 10.0 3.2 84 3.2 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Dynamin_M PF01031.15 OAJ01441.1 - 6.4e-113 376.4 0.0 9.9e-113 375.7 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 OAJ01441.1 - 2.6e-54 183.5 0.0 5.3e-54 182.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 OAJ01441.1 - 1.3e-28 98.6 0.4 8.2e-28 96.1 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 OAJ01441.1 - 0.0053 16.7 0.1 0.051 13.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ01441.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Phage_T4_gp19 PF06841.7 OAJ01441.1 - 0.086 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 Sporozoite_P67 PF05642.6 OAJ01441.1 - 1.6 6.4 11.6 2.5 5.8 8.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HRXXH PF13933.1 OAJ01445.1 - 1.1e-82 277.1 0.0 1.5e-82 276.7 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family MVL PF12151.3 OAJ01445.1 - 0.09 12.4 2.5 0.23 11.1 1.8 1.7 1 0 0 1 1 1 0 Mannan-binding protein Zip PF02535.17 OAJ01447.1 - 9.4e-36 123.4 21.8 1.3e-35 122.9 9.6 2.4 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3681 PF12442.3 OAJ01447.1 - 0.6 10.3 5.7 1.8 8.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) DUF2373 PF10180.4 OAJ01448.1 - 2.9e-14 52.3 1.0 5.9e-10 38.5 0.5 2.5 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Macoilin PF09726.4 OAJ01448.1 - 0.15 10.2 21.7 0.21 9.8 15.0 1.2 1 0 0 1 1 1 0 Transmembrane protein INCENP_ARK-bind PF03941.10 OAJ01448.1 - 1.5 8.7 7.4 2 8.3 0.5 2.7 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region BLVR PF06375.6 OAJ01448.1 - 9.2 6.0 29.4 0.25 11.1 6.8 3.0 2 1 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Pro_isomerase PF00160.16 OAJ01449.1 - 3.5e-41 140.9 0.0 9e-41 139.6 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 OAJ01449.1 - 0.0015 17.8 1.2 0.0043 16.2 0.1 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger SSP160 PF06933.6 OAJ01449.1 - 5.1 4.9 14.3 1 7.2 7.5 1.5 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF1295 PF06966.7 OAJ01450.1 - 1.1e-34 119.7 0.1 5.8e-34 117.4 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) MFS_1 PF07690.11 OAJ01451.1 - 2.5e-16 59.3 7.3 2.6e-06 26.4 0.0 3.8 4 0 0 4 4 4 3 Major Facilitator Superfamily ThiF PF00899.16 OAJ01452.1 - 2.6e-33 114.7 0.0 4.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family Neur_chan_memb PF02932.11 OAJ01452.1 - 0.078 12.8 8.3 0.053 13.4 1.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TrkA_N PF02254.13 OAJ01452.1 - 0.11 12.4 0.6 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain GTP_cyclohydro2 PF00925.15 OAJ01453.1 - 2.2e-62 209.2 0.0 1.5e-56 190.2 0.0 2.4 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF3138 PF11336.3 OAJ01453.1 - 1.4 7.0 6.3 2.4 6.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FHA PF00498.21 OAJ01454.1 - 0.032 14.3 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 FHA domain Sigma70_r1_2 PF00140.15 OAJ01455.1 - 0.016 14.8 0.2 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 DEAD PF00270.24 OAJ01456.1 - 1.4e-40 138.5 0.1 2.9e-40 137.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01456.1 - 2.2e-20 72.3 0.0 4.3e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01456.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ01456.1 - 0.042 12.6 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF4545 PF15078.1 OAJ01457.1 - 0.051 12.4 0.1 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) SPT6_acidic PF14632.1 OAJ01457.1 - 0.066 13.3 0.0 0.26 11.4 0.0 1.8 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Abhydrolase_6 PF12697.2 OAJ01458.1 - 3.6e-21 76.1 0.1 5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ01458.1 - 2.7e-17 62.8 0.2 3.4e-16 59.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ01458.1 - 2.2e-10 40.1 0.0 2.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 OAJ01458.1 - 6.7e-10 37.9 0.0 9.4e-06 24.3 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 OAJ01458.1 - 2.3e-09 37.0 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 OAJ01458.1 - 1.3e-08 34.3 0.0 4e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 OAJ01458.1 - 1.5e-06 27.9 0.0 8.2e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ01458.1 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 OAJ01458.1 - 0.00068 19.1 0.1 0.048 13.0 0.1 2.1 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.3 OAJ01458.1 - 0.0012 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 OAJ01458.1 - 0.0031 16.1 0.0 0.0047 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 OAJ01458.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 OAJ01458.1 - 0.01 14.1 0.0 0.84 7.8 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S28 PF05577.7 OAJ01458.1 - 0.017 13.7 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MIP-T3 PF10243.4 OAJ01459.1 - 0.082 11.3 18.1 0.079 11.4 12.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Serglycin PF04360.7 OAJ01461.1 - 0.041 13.6 0.4 0.041 13.6 0.3 1.9 2 0 0 2 2 2 0 Serglycin TFIID-18kDa PF02269.11 OAJ01462.1 - 2.1e-07 30.6 0.3 2.8e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit EF-hand_7 PF13499.1 OAJ01463.1 - 4.5e-13 49.1 0.0 4.3e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ01463.1 - 2.9e-12 45.3 0.3 2.4e-05 23.8 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 OAJ01463.1 - 3.7e-12 44.5 0.1 1.1e-05 24.4 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 OAJ01463.1 - 9.6e-09 35.0 0.0 5e-05 23.1 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 OAJ01463.1 - 3.3e-05 23.4 0.4 0.013 15.1 0.0 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 OAJ01463.1 - 0.0011 18.2 0.1 0.079 12.3 0.0 2.8 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 OAJ01463.1 - 0.025 14.5 0.0 0.17 11.9 0.0 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.8 OAJ01463.1 - 0.05 13.2 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Abhydrolase_6 PF12697.2 OAJ01464.1 - 4.3e-22 79.1 0.2 6e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ01464.1 - 1.1e-17 64.1 0.6 2.3e-16 59.8 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAJ01464.1 - 2.9e-10 39.1 0.1 1.9e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 OAJ01464.1 - 1.6e-09 37.3 0.1 5.4e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAJ01464.1 - 2.6e-09 36.6 0.0 1.8e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 OAJ01464.1 - 1.2e-08 34.7 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 OAJ01464.1 - 6.2e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 OAJ01464.1 - 8.3e-06 25.5 0.0 8.4e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 OAJ01464.1 - 0.00064 18.1 0.1 0.68 8.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 OAJ01464.1 - 0.0019 17.7 0.1 0.017 14.5 0.0 2.1 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 OAJ01464.1 - 0.0053 16.5 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 OAJ01464.1 - 0.0074 15.8 0.1 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S28 PF05577.7 OAJ01464.1 - 0.0099 14.4 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF1100 PF06500.6 OAJ01464.1 - 0.011 14.3 0.0 0.042 12.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1100) zf-C3HC4_2 PF13923.1 OAJ01465.1 - 0.21 11.6 11.6 0.37 10.8 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin PF00085.15 OAJ01466.1 - 4.7e-19 67.9 0.0 5.5e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ01466.1 - 0.00022 21.2 0.0 0.014 15.5 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ01466.1 - 0.0057 16.8 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.3 OAJ01466.1 - 0.057 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) TraF PF13728.1 OAJ01466.1 - 0.066 12.6 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.6 OAJ01466.1 - 0.08 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE FCH PF00611.18 OAJ01467.1 - 9.3e-17 61.0 0.3 2.7e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 OAJ01467.1 - 4.6e-11 41.9 0.1 9.2e-11 40.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ01467.1 - 4.4e-09 35.7 0.0 8.8e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ01467.1 - 2.8e-07 29.9 0.0 5.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AA_permease PF00324.16 OAJ01471.1 - 2.7e-114 382.1 31.4 3.1e-114 381.9 21.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ01471.1 - 1.5e-39 135.7 33.5 2e-39 135.3 23.2 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 OAJ01476.1 - 2.5e-56 191.2 2.5 7.8e-55 186.3 1.7 2.7 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 OAJ01476.1 - 2.6e-19 69.4 0.0 1.1e-18 67.4 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.1 OAJ01476.1 - 1.9e-05 24.6 0.0 6.9e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ01476.1 - 0.00034 20.5 0.0 0.00092 19.1 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ01476.1 - 0.00051 18.6 0.0 0.00078 18.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 OAJ01476.1 - 0.00051 19.0 0.0 0.0011 17.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ01476.1 - 0.00087 18.3 0.1 0.0013 17.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ01476.1 - 0.002 18.1 0.0 0.024 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ01476.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 OAJ01476.1 - 0.0027 16.6 0.2 0.0064 15.3 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 OAJ01476.1 - 0.0045 15.6 0.0 0.0068 15.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase ApbA PF02558.11 OAJ01476.1 - 0.0064 15.9 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 OAJ01476.1 - 0.031 14.6 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ01476.1 - 0.048 12.5 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 OAJ01476.1 - 0.083 12.7 0.2 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 OAJ01476.1 - 0.085 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 OAJ01476.1 - 0.13 11.0 0.0 0.3 9.8 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 OAJ01476.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 OAJ01476.1 - 0.23 11.4 0.0 0.84 9.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Kinesin PF00225.18 OAJ01477.1 - 3e-109 364.7 0.0 4.5e-109 364.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Atg14 PF10186.4 OAJ01477.1 - 0.014 14.3 2.2 0.024 13.6 1.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 OAJ01477.1 - 0.31 9.1 2.2 0.48 8.5 1.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Apolipoprotein PF01442.13 OAJ01477.1 - 0.41 10.1 9.6 0.97 8.9 6.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Y_phosphatase2 PF03162.8 OAJ01478.1 - 4.7e-45 152.9 0.0 6.9e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.9 OAJ01478.1 - 3.3e-38 131.3 4.2 4.9e-38 130.8 2.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.1 OAJ01478.1 - 4.9e-06 26.8 0.0 2.8e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family zf-4CXXC_R1 PF10497.4 OAJ01478.1 - 0.15 12.2 3.2 1.7 8.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Myc_N PF01056.13 OAJ01478.1 - 0.72 8.9 4.9 5.4 6.0 1.4 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DnaJ PF00226.26 OAJ01479.1 - 1.3e-16 60.1 0.9 2.3e-16 59.2 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L29e PF01779.12 OAJ01480.1 - 7.4e-24 83.3 9.9 1e-23 82.8 6.8 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Acetyltransf_1 PF00583.19 OAJ01481.1 - 2.2e-13 49.9 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ01481.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ01481.1 - 0.00058 19.9 0.0 0.00077 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ01481.1 - 0.03 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein JAB PF01398.16 OAJ01482.1 - 9e-35 118.8 0.1 1.9e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 OAJ01482.1 - 7.6e-28 96.9 1.7 1.9e-27 95.6 1.2 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 OAJ01482.1 - 7.4e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TRP PF06011.7 OAJ01484.1 - 3.5e-50 170.8 13.4 9.5e-34 116.7 4.8 2.2 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel FLO_LFY PF01698.11 OAJ01484.1 - 0.12 11.1 1.9 0.22 10.3 1.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4366 PF14283.1 OAJ01484.1 - 0.14 11.5 0.2 0.28 10.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4611 PF15387.1 OAJ01484.1 - 5.5 7.2 6.3 12 6.1 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Mannosyl_trans2 PF04188.8 OAJ01485.1 - 2.6e-57 194.7 13.9 3.4e-57 194.3 9.6 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) GSAP-16 PF14959.1 OAJ01485.1 - 0.18 11.5 0.4 0.35 10.6 0.3 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term CagX PF03524.10 OAJ01486.1 - 0.43 9.8 6.7 1.2 8.3 4.6 1.7 1 0 0 1 1 1 0 Conjugal transfer protein Suc_Fer-like PF06999.7 OAJ01487.1 - 9.1e-28 97.8 0.0 2.9e-27 96.1 0.0 1.9 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Tau95 PF09734.4 OAJ01488.1 - 1.5e-38 132.8 0.0 2.6e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DSS1_SEM1 PF05160.8 OAJ01489.1 - 2.4e-18 65.6 11.2 3.6e-12 45.8 2.2 2.2 2 0 0 2 2 2 2 DSS1/SEM1 family K_channel_TID PF07941.6 OAJ01489.1 - 0.033 14.4 10.6 0.033 14.4 7.3 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SWIRM PF04433.12 OAJ01490.1 - 9.2e-15 54.5 0.0 2.4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 OAJ01490.1 - 4.3e-10 39.4 0.0 1.1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 OAJ01490.1 - 5.4e-09 35.4 7.2 9e-09 34.7 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 OAJ01490.1 - 3.4e-06 27.0 0.0 1.1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain RNA_pol_Rpb4 PF03874.11 OAJ01490.1 - 0.15 12.0 0.6 0.29 11.1 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF3602 PF12223.3 OAJ01491.1 - 1.8e-13 50.6 26.2 4.7e-06 26.8 1.1 4.5 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) Creb_binding PF09030.5 OAJ01491.1 - 0.091 12.9 0.1 0.38 10.9 0.0 2.0 2 1 0 2 2 2 0 Creb binding DUF1509 PF07420.6 OAJ01491.1 - 0.9 8.7 10.0 1.1 8.4 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PIG-F PF06699.6 OAJ01492.1 - 3.2e-16 59.8 9.5 3.2e-16 59.8 6.6 2.0 1 1 0 2 2 2 1 GPI biosynthesis protein family Pig-F ATP-synt_A PF00119.15 OAJ01492.1 - 4.3 6.7 11.7 0.057 12.9 2.2 2.0 2 1 0 2 2 2 0 ATP synthase A chain DUF1900 PF08954.6 OAJ01495.1 - 4.6e-48 162.1 0.0 6e-22 77.6 0.0 3.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1900) WD40 PF00400.27 OAJ01495.1 - 0.00031 20.5 0.1 0.94 9.4 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat IKI3 PF04762.7 OAJ01495.1 - 0.22 9.2 0.1 3 5.5 0.0 2.0 2 0 0 2 2 2 0 IKI3 family MFS_1 PF07690.11 OAJ01496.1 - 4.2e-32 111.2 43.4 1e-30 106.6 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_target_1 PF15179.1 OAJ01496.1 - 0.23 11.0 0.9 0.55 9.7 0.0 2.0 2 0 0 2 2 2 0 Myc target protein 1 WD40 PF00400.27 OAJ01498.1 - 6.9e-13 47.9 1.0 0.71 9.8 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat FA_desaturase PF00487.19 OAJ01499.1 - 1.8e-25 89.8 17.5 3.4e-25 88.9 12.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 OAJ01499.1 - 2.9e-16 58.3 0.2 5.1e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Mpv17_PMP22 PF04117.7 OAJ01500.1 - 3.6e-08 32.9 1.0 6.4e-07 28.9 1.0 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PqqD PF05402.7 OAJ01500.1 - 0.085 12.8 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) RRM_1 PF00076.17 OAJ01501.1 - 6.6e-19 67.3 0.0 1.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ01501.1 - 1.9e-10 40.5 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ01501.1 - 5.4e-08 32.5 0.0 8.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ01501.1 - 0.0093 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Tim17 PF02466.14 OAJ01502.1 - 2.2e-36 124.7 5.0 3.2e-36 124.1 3.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 OAJ01502.1 - 0.078 12.9 0.4 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) DUF4117 PF13491.1 OAJ01502.1 - 0.16 11.3 1.7 1.5 8.1 1.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) DUF4448 PF14610.1 OAJ01503.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 OAJ01503.1 - 0.026 15.0 0.1 0.051 14.0 0.1 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3377 PF11857.3 OAJ01503.1 - 0.21 11.2 0.1 0.43 10.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) IKI3 PF04762.7 OAJ01504.1 - 5.1e-234 779.1 0.0 8.3e-234 778.4 0.0 1.4 1 1 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.3 OAJ01504.1 - 0.00059 19.8 3.1 0.0074 16.3 0.5 2.9 2 0 0 2 2 2 1 Selenocysteine synthase N terminal TPR_2 PF07719.12 OAJ01504.1 - 0.026 14.4 1.6 0.23 11.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 OAJ01504.1 - 0.034 13.7 0.5 0.27 10.8 0.1 2.7 2 1 1 3 3 3 0 Region in Clathrin and VPS Plus-3 PF03126.13 OAJ01506.1 - 0.0019 18.2 0.0 0.0046 16.9 0.0 1.6 2 0 0 2 2 2 1 Plus-3 domain Myb_DNA-bind_6 PF13921.1 OAJ01508.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 OAJ01508.1 - 0.029 14.2 0.1 7.6 6.5 0.1 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ01508.1 - 0.055 13.6 0.1 0.061 13.4 0.0 1.1 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ01508.1 - 0.057 13.4 0.1 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain MBOAT PF03062.14 OAJ01509.1 - 5.2e-31 107.9 14.7 5.2e-31 107.9 10.2 2.9 3 1 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family Sec10 PF07393.6 OAJ01510.1 - 0.063 11.4 0.3 0.076 11.1 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF1758 PF05585.7 OAJ01510.1 - 0.097 12.2 0.7 0.16 11.5 0.1 1.5 2 0 0 2 2 2 0 Putative peptidase (DUF1758) AMP-binding PF00501.23 OAJ01511.1 - 3.1e-69 233.3 0.0 3.9e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ01511.1 - 8.6e-08 33.0 0.1 1.9e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.4 OAJ01511.1 - 0.036 14.4 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 Prp19_bind PF06991.6 OAJ01512.1 - 5.5e-61 206.2 24.6 5.5e-61 206.2 17.0 2.1 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 OAJ01512.1 - 0.19 11.7 1.4 0.59 10.1 1.0 1.9 1 1 0 1 1 1 0 Zinc knuckle THF_DHG_CYH PF00763.18 OAJ01513.1 - 1.3e-16 60.6 0.0 8.2e-07 29.0 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 OAJ01513.1 - 1.8e-13 49.8 0.3 4.1e-08 32.4 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain VKG_Carbox PF05090.9 OAJ01513.1 - 0.094 11.5 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase PIF1 PF05970.9 OAJ01517.1 - 2e-21 76.3 0.2 4.2e-21 75.2 0.0 1.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01517.1 - 3.2e-12 46.4 0.0 2.3e-11 43.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ01517.1 - 1.1e-10 41.5 0.1 3.7e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ01517.1 - 4.3e-07 29.5 4.2 4.7e-06 26.2 0.1 3.4 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ01517.1 - 0.0098 15.8 0.7 0.057 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAJ01517.1 - 0.068 13.2 0.2 0.5 10.4 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 OAJ01517.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ01517.1 - 0.1 12.3 0.2 0.58 9.8 0.1 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Apolipoprotein PF01442.13 OAJ01520.1 - 0.0086 15.6 0.7 0.019 14.4 0.5 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.6 OAJ01520.1 - 0.012 14.7 1.6 0.018 14.1 1.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 OAJ01520.1 - 0.027 14.2 3.0 2 8.2 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 OAJ01520.1 - 0.052 13.9 1.6 2.8 8.3 0.1 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Med11 PF10280.4 OAJ01520.1 - 0.075 13.0 0.8 0.2 11.7 0.3 1.8 1 1 1 2 2 2 0 Mediator complex protein Fzo_mitofusin PF04799.8 OAJ01520.1 - 0.26 10.6 1.1 0.78 9.1 0.2 1.9 1 1 1 2 2 2 0 fzo-like conserved region Cyclin_N PF00134.18 OAJ01521.1 - 6.9e-22 77.3 0.6 1.9e-18 66.2 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ01521.1 - 3.4e-05 23.7 0.1 7.4e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pkinase PF00069.20 OAJ01522.1 - 1.7e-58 197.8 0.0 2.3e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01522.1 - 1.1e-35 122.9 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01522.1 - 7.1e-08 31.7 0.0 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ01522.1 - 9.1e-08 32.1 0.1 1.2e-05 25.1 0.0 2.5 1 1 2 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ01522.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Herpes_DNAp_acc PF04929.7 OAJ01524.1 - 1.3 7.8 3.6 1.8 7.4 2.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Snapin_Pallidin PF14712.1 OAJ01525.1 - 0.065 13.5 0.1 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 Snapin/Pallidin PVL_ORF50 PF07768.6 OAJ01525.1 - 0.32 11.0 2.4 0.42 10.6 1.7 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family DASH_Spc34 PF08657.5 OAJ01525.1 - 0.5 9.9 3.1 0.62 9.6 2.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF349 PF03993.7 OAJ01525.1 - 0.77 9.9 3.4 1.6 8.9 0.9 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) DDE_Tnp_4 PF13359.1 OAJ01526.1 - 0.0001 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.9 OAJ01527.1 - 3.1e-18 65.1 0.0 7.6e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DNA_pol_lambd_f PF10391.4 OAJ01527.1 - 0.12 11.9 0.1 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Histone PF00125.19 OAJ01528.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ01528.1 - 0.044 13.9 0.1 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 OAJ01528.1 - 0.089 12.5 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pex14_N PF04695.8 OAJ01528.1 - 0.17 11.9 1.3 0.28 11.2 0.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AT_hook PF02178.14 OAJ01528.1 - 0.21 11.3 5.8 0.51 10.1 4.0 1.7 1 0 0 1 1 1 0 AT hook motif RFX5_DNA_bdg PF14621.1 OAJ01528.1 - 1.1 8.8 11.1 1.5 8.3 7.7 1.1 1 0 0 1 1 1 0 RFX5 DNA-binding domain Pkinase PF00069.20 OAJ01529.1 - 4.4e-48 163.7 0.0 8.7e-48 162.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01529.1 - 1.2e-28 99.9 0.0 3.1e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2205 PF10224.4 OAJ01529.1 - 0.0056 16.2 1.7 0.0056 16.2 1.2 3.2 3 1 1 4 4 3 1 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 OAJ01529.1 - 0.013 15.4 1.3 0.013 15.4 0.9 3.6 3 1 1 4 4 4 0 bZIP transcription factor DivIC PF04977.10 OAJ01529.1 - 0.015 14.7 1.3 0.015 14.7 0.9 3.9 2 2 3 5 5 5 0 Septum formation initiator Rab5-bind PF09311.6 OAJ01529.1 - 0.019 14.8 38.3 0.096 12.5 13.8 2.4 1 1 1 2 2 2 0 Rabaptin-like protein HALZ PF02183.13 OAJ01529.1 - 0.021 14.5 5.6 3 7.6 0.2 3.2 1 1 0 2 2 2 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 OAJ01529.1 - 0.081 12.7 0.2 0.081 12.7 0.1 4.4 3 1 1 4 4 4 0 Basic region leucine zipper Scaffolding_pro PF11418.3 OAJ01529.1 - 0.32 11.3 6.7 0.25 11.6 1.7 2.5 1 1 1 2 2 2 0 Phi29 scaffolding protein ERM PF00769.14 OAJ01529.1 - 0.74 9.3 31.7 0.068 12.7 12.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF972 PF06156.8 OAJ01529.1 - 0.79 10.0 16.8 0.43 10.9 2.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Spectrin PF00435.16 OAJ01529.1 - 1.4 9.2 17.2 0.058 13.6 2.1 2.8 2 0 0 2 2 2 0 Spectrin repeat BLOC1_2 PF10046.4 OAJ01529.1 - 1.4 9.1 10.6 0.19 11.8 1.8 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 OAJ01529.1 - 2.7 7.8 30.9 0.042 13.6 2.9 4.3 1 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 OAJ01529.1 - 3.5 7.5 32.8 0.15 11.9 9.2 3.2 3 1 1 4 4 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 OAJ01529.1 - 9.2 6.1 26.6 0.012 15.4 6.2 2.7 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 OAJ01529.1 - 9.8 5.6 16.3 0.5 9.8 4.0 2.6 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NTP_transf_2 PF01909.18 OAJ01530.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Transglut_i_TM PF14400.1 OAJ01531.1 - 0.05 13.1 1.2 0.069 12.6 0.8 1.3 1 1 0 1 1 1 0 Inactive transglutaminase fused to 7 transmembrane helices RR_TM4-6 PF06459.7 OAJ01531.1 - 0.67 9.8 2.5 0.83 9.4 1.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.8 OAJ01531.1 - 0.74 8.8 6.7 0.84 8.6 4.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pol_alpha_B_N PF08418.5 OAJ01531.1 - 1.4 8.4 8.3 1.9 7.9 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal rve PF00665.21 OAJ01532.1 - 1.1e-17 64.2 0.0 2.5e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Oxygenase-NA PF09859.4 OAJ01532.1 - 0.17 11.2 0.0 0.4 9.9 0.0 1.6 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Med3 PF11593.3 OAJ01533.1 - 4.2 6.4 10.0 0.023 13.9 0.7 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Asp_protease_2 PF13650.1 OAJ01534.1 - 2.4e-05 24.7 0.0 5.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ01534.1 - 0.0081 16.0 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ01534.1 - 0.011 15.5 0.1 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 OAJ01534.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) MotB_plug PF13677.1 OAJ01542.1 - 0.63 9.3 5.3 5.7 6.3 0.4 2.6 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB CRAL_TRIO PF00650.15 OAJ01544.1 - 1.3e-26 92.9 0.0 1.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ01544.1 - 9.2e-10 38.5 1.0 3.2e-09 36.7 0.7 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Zn_clus PF00172.13 OAJ01545.1 - 2.8e-06 27.1 5.8 4.4e-06 26.4 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S18 PF01084.15 OAJ01546.1 - 7e-18 64.2 0.0 1.4e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 SR-25 PF10500.4 OAJ01546.1 - 0.37 10.2 25.9 0.61 9.5 18.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 OAJ01546.1 - 0.66 9.3 16.2 0.76 9.1 11.2 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 OAJ01546.1 - 6.3 4.9 16.7 8 4.6 11.6 1.0 1 0 0 1 1 1 0 Transmembrane protein EMP24_GP25L PF01105.19 OAJ01547.1 - 2.2e-42 144.8 0.0 3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Syndecan PF01034.15 OAJ01547.1 - 0.67 9.6 0.1 0.67 9.6 0.0 2.0 2 0 0 2 2 2 0 Syndecan domain SNARE PF05739.14 OAJ01548.1 - 2.9e-10 39.6 1.9 2.9e-10 39.6 1.3 2.4 3 0 0 3 3 3 1 SNARE domain Spectrin PF00435.16 OAJ01548.1 - 0.039 14.2 0.5 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Spectrin repeat PilJ PF13675.1 OAJ01548.1 - 0.12 12.6 0.2 0.12 12.6 0.1 2.4 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term bZIP_C PF12498.3 OAJ01548.1 - 0.36 12.0 5.7 0.18 13.0 1.8 1.9 2 0 0 2 2 2 0 Basic leucine-zipper C terminal NiFe_hyd_SSU_C PF14720.1 OAJ01549.1 - 0.022 14.7 0.0 15 5.6 0.0 3.1 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Coronavirus_5 PF05528.6 OAJ01549.1 - 0.026 14.3 0.0 3.9 7.3 0.0 3.7 3 0 0 3 3 3 0 Coronavirus gene 5 protein QueF_N PF14819.1 OAJ01549.1 - 0.05 13.6 2.5 21 5.2 0.0 4.5 3 2 3 6 6 6 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Lipase_GDSL_3 PF14606.1 OAJ01549.1 - 0.095 12.4 3.2 29 4.3 0.0 4.2 2 1 2 4 4 4 0 GDSL-like Lipase/Acylhydrolase family Stap_Strp_tox_C PF02876.12 OAJ01549.1 - 0.11 12.6 17.5 20 5.4 0.1 7.0 8 1 1 9 9 9 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Cadherin_2 PF08266.7 OAJ01549.1 - 0.11 12.0 7.3 6.9 6.3 0.1 4.9 2 1 0 4 4 4 0 Cadherin-like Lon_C PF05362.8 OAJ01550.1 - 2.8e-66 222.7 0.2 6.8e-66 221.4 0.1 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 OAJ01550.1 - 5.5e-31 107.8 0.0 1e-30 106.9 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 OAJ01550.1 - 1.6e-21 76.8 0.0 5.7e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 OAJ01550.1 - 5.1e-07 29.2 0.0 1.7e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 OAJ01550.1 - 6.5e-06 25.9 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.6 OAJ01550.1 - 2.9e-05 22.9 0.0 5.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 OAJ01550.1 - 5.5e-05 23.2 0.6 0.00047 20.1 0.0 2.9 3 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 OAJ01550.1 - 0.00089 19.4 0.2 0.038 14.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ01550.1 - 0.001 19.8 0.3 0.0035 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ01550.1 - 0.0015 17.5 0.0 0.0079 15.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ01550.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ01550.1 - 0.0071 16.6 1.3 0.012 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ01550.1 - 0.019 14.3 0.0 0.055 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 OAJ01550.1 - 0.026 13.2 3.1 0.9 8.1 0.0 2.6 3 0 0 3 3 3 0 TIP49 C-terminus Arch_ATPase PF01637.13 OAJ01550.1 - 0.027 14.1 1.4 8.5 5.9 0.0 3.4 2 1 0 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 OAJ01550.1 - 0.047 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ01550.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 OAJ01550.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF605 PF04652.11 OAJ01550.1 - 0.83 8.9 42.5 2 7.7 7.5 3.2 3 0 0 3 3 3 0 Vta1 like Peptidase_C37 PF05416.7 OAJ01551.1 - 0.11 10.8 2.3 0.16 10.2 1.6 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Histone PF00125.19 OAJ01553.1 - 2.3e-26 91.7 1.6 3.9e-26 90.9 1.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ01553.1 - 6.5e-06 26.2 0.1 1e-05 25.6 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ01553.1 - 0.0026 17.0 1.7 0.0035 16.6 1.0 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T Cytidylate_kin PF02224.13 OAJ01553.1 - 0.0099 15.3 0.3 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Cytidylate kinase DUF3458 PF11940.3 OAJ01553.1 - 0.064 12.0 0.2 0.091 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) CBFD_NFYB_HMF PF00808.18 OAJ01553.1 - 0.1 12.6 0.4 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Transposase_21 PF02992.9 OAJ01554.1 - 1e-21 77.0 0.0 1.6e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ01554.1 - 0.0026 17.1 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SLT_2 PF13406.1 OAJ01555.1 - 0.63 8.9 4.9 0.95 8.3 3.4 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain HK97-gp10_like PF04883.7 OAJ01555.1 - 0.65 10.9 3.9 31 5.5 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component FUSC-like PF12805.2 OAJ01555.1 - 1.6 7.6 4.7 1.1 8.0 2.1 1.5 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS TSC22 PF01166.13 OAJ01555.1 - 6.5 6.7 7.9 18 5.3 0.0 3.4 3 1 1 4 4 4 0 TSC-22/dip/bun family OPT PF03169.10 OAJ01557.1 - 3.8e-189 630.1 56.0 4.4e-189 629.9 38.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUDIX PF00293.23 OAJ01558.1 - 3.8e-12 45.9 0.0 1.6e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Toxin_11 PF07473.6 OAJ01560.1 - 2.9 7.8 7.8 1 9.3 0.2 3.2 3 0 0 3 3 3 0 Spasmodic peptide gm9a Glycos_transf_1 PF00534.15 OAJ01561.1 - 3.1e-26 91.8 0.0 4.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAJ01561.1 - 1.5e-12 47.7 0.1 3e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ01561.1 - 2.4e-06 27.7 0.0 5.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ01561.1 - 0.002 17.8 0.2 0.0058 16.3 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 KNTase_C PF07827.6 OAJ01561.1 - 0.08 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 KNTase C-terminal domain TPR_11 PF13414.1 OAJ01564.1 - 1.8e-51 171.6 29.2 3.3e-15 55.4 1.5 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 OAJ01564.1 - 2.1e-46 153.6 22.9 8.6e-05 21.9 0.2 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01564.1 - 8.9e-34 112.6 22.5 0.0022 17.7 0.0 9.7 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ01564.1 - 8.7e-23 80.4 13.9 1.4e-06 28.7 0.3 6.8 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01564.1 - 6.3e-22 77.2 18.9 7.2e-11 41.8 1.1 6.3 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ01564.1 - 6.5e-18 63.0 20.8 0.021 14.5 0.0 9.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ01564.1 - 1.1e-15 56.6 16.8 0.19 12.4 0.0 9.8 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ01564.1 - 4.4e-13 48.3 6.4 0.11 12.7 0.0 7.4 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ01564.1 - 9.5e-09 35.4 15.5 0.00036 20.8 0.1 6.5 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ01564.1 - 1.8e-08 34.1 5.5 0.023 14.5 0.0 6.1 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ01564.1 - 5.9e-07 28.8 14.8 0.02 14.6 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ01564.1 - 0.00042 20.5 14.4 24 5.6 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ01564.1 - 0.00096 19.2 11.8 0.033 14.3 1.6 4.2 3 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 OAJ01564.1 - 0.019 14.8 5.0 3.1 7.8 0.2 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 OAJ01564.1 - 0.12 12.2 2.6 5.1 6.9 0.0 4.5 4 0 0 4 4 4 0 Exonuclease VII small subunit XPC-binding PF09280.6 OAJ01564.1 - 2.6 7.5 5.8 1.8 8.0 1.3 2.7 2 0 0 2 2 2 0 XPC-binding domain AAR2 PF05282.6 OAJ01564.1 - 6.8 5.5 8.3 0.3 9.9 0.2 2.1 1 1 0 2 2 2 0 AAR2 protein Ndc1_Nup PF09531.5 OAJ01564.1 - 8.7 4.6 7.4 3.7 5.8 0.3 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DIOX_N PF14226.1 OAJ01565.1 - 1.5e-09 38.4 0.1 3.1e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ01565.1 - 1.3e-07 31.8 0.0 4.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_31 PF01055.21 OAJ01566.1 - 8e-142 473.1 1.3 1e-141 472.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 OAJ01566.1 - 1.2e-19 69.9 0.0 4.3e-19 68.1 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Bromodomain PF00439.20 OAJ01567.1 - 8.1e-18 64.1 0.1 2.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.15 OAJ01567.1 - 9.2e-09 34.8 0.1 0.0011 18.1 0.0 3.9 4 0 0 4 4 4 2 Peptidase family M1 HEAT_2 PF13646.1 OAJ01567.1 - 8.3e-06 26.0 0.6 0.026 14.7 0.0 3.7 4 0 0 4 4 4 2 HEAT repeats RasGEF PF00617.14 OAJ01568.1 - 3.2e-61 206.3 0.2 5.4e-61 205.5 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ01568.1 - 7.8e-27 93.4 0.2 7.8e-27 93.4 0.2 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAJ01568.1 - 1.7e-13 49.9 0.2 3.6e-13 48.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ01568.1 - 3.1e-13 48.8 0.1 7.9e-13 47.5 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ01568.1 - 1.7e-11 43.4 0.0 3.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Med15 PF09606.5 OAJ01568.1 - 4e-06 25.3 45.7 4e-06 25.3 31.7 5.7 5 1 1 7 7 7 1 ARC105 or Med15 subunit of Mediator complex non-fungal WW PF00397.21 OAJ01568.1 - 0.0075 16.1 1.8 0.14 12.0 0.1 2.5 2 0 0 2 2 2 1 WW domain PQQ PF01011.16 OAJ01568.1 - 0.029 13.9 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Proteasome PF00227.21 OAJ01569.1 - 7.2e-32 110.2 0.0 8.6e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_binding_7 PF13241.1 OAJ01570.1 - 9.7e-28 96.4 0.0 1.6e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 OAJ01570.1 - 1.9e-21 75.0 0.1 2.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 OAJ01570.1 - 4.1e-10 38.4 0.1 7.2e-10 37.6 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 OAJ01570.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S28e PF01200.13 OAJ01571.1 - 9.7e-32 108.5 1.0 1e-31 108.4 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e DUF788 PF05620.6 OAJ01572.1 - 4.6e-36 124.2 0.1 5.8e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF788) RR_TM4-6 PF06459.7 OAJ01573.1 - 0.59 9.9 3.8 0.83 9.4 2.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_22 PF03901.12 OAJ01574.1 - 5.9e-69 233.0 10.4 3.5e-67 227.2 7.4 2.2 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family Epimerase PF01370.16 OAJ01575.1 - 2.9e-39 134.9 0.0 4.1e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 OAJ01575.1 - 2e-24 85.2 0.0 4.6e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 OAJ01575.1 - 5.2e-12 45.0 0.0 1.1e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ01575.1 - 7.4e-08 31.6 0.2 1.2e-07 30.9 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 OAJ01575.1 - 1e-07 31.1 0.0 1.9e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 OAJ01575.1 - 4.6e-07 29.8 0.0 8.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ01575.1 - 9.8e-06 25.6 0.0 0.00019 21.4 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAJ01575.1 - 2.4e-05 23.3 0.0 0.0002 20.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 OAJ01575.1 - 6.4e-05 22.6 0.2 0.00022 20.9 0.1 1.8 1 1 0 1 1 1 1 KR domain Ribonuc_L-PSP PF01042.16 OAJ01575.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP UEV PF05743.8 OAJ01577.1 - 3.3e-40 136.5 0.1 5.2e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 OAJ01577.1 - 1.2e-25 88.9 0.6 2.4e-25 87.9 0.4 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 OAJ01577.1 - 0.0011 18.4 0.2 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CorA PF01544.13 OAJ01578.1 - 1.8e-08 33.7 2.1 3.1e-08 33.0 1.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CENP-U PF13097.1 OAJ01578.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit Pox_F11 PF04943.7 OAJ01578.1 - 1.1 8.0 3.6 0.34 9.7 0.5 1.5 2 0 0 2 2 2 0 Poxvirus F11 protein RNase_PH PF01138.16 OAJ01579.1 - 1.9e-19 70.2 0.0 4e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ01579.1 - 1e-05 25.3 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 BSP_II PF05432.6 OAJ01579.1 - 0.03 13.6 2.6 0.042 13.1 1.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_S13 PF00416.17 OAJ01580.1 - 1.2e-38 131.7 1.0 1.4e-38 131.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 OAJ01580.1 - 0.0093 14.5 0.0 0.0095 14.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 OAJ01580.1 - 0.013 15.5 0.1 0.032 14.2 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif WD40 PF00400.27 OAJ01581.1 - 2.4e-19 68.3 0.2 7.8e-05 22.4 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat YhfZ_C PF14503.1 OAJ01581.1 - 0.12 11.7 0.1 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain MMS1_N PF10433.4 OAJ01581.1 - 0.14 10.2 0.0 4.7 5.2 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Exo_endo_phos PF03372.18 OAJ01582.1 - 9.4e-18 65.0 0.3 1.6e-17 64.3 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 OAJ01582.1 - 0.047 13.6 0.2 1.5 8.8 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat Imm1 PF14430.1 OAJ01582.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 Immunity protein Imm1 Cytochrom_D1 PF02239.11 OAJ01582.1 - 0.11 10.7 0.0 0.18 10.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Enkurin PF13864.1 OAJ01582.1 - 0.97 9.6 3.7 7 6.9 0.1 2.4 2 0 0 2 2 2 0 Calmodulin-binding Cation_efflux PF01545.16 OAJ01583.1 - 3.6e-60 203.4 4.7 3.6e-60 203.4 3.3 2.6 2 2 0 2 2 2 1 Cation efflux family DUF1713 PF08213.6 OAJ01584.1 - 5.7e-10 38.6 25.4 8.6e-10 38.0 17.6 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pacs-1 PF10254.4 OAJ01584.1 - 2.4 6.6 6.3 1.2 7.7 3.1 1.3 1 1 0 1 1 1 0 PACS-1 cytosolic sorting protein ARL6IP6 PF15062.1 OAJ01585.1 - 1.9 8.4 7.3 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix MULE PF10551.4 OAJ01589.1 - 2.3e-19 69.3 0.0 9.6e-19 67.3 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 OAJ01589.1 - 6.2e-08 31.5 0.0 1.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family Pellino PF04710.9 OAJ01589.1 - 0.1 11.1 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Pellino MFS_1 PF07690.11 OAJ01590.1 - 1.1e-27 96.6 83.7 7.6e-22 77.4 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ01590.1 - 0.0017 18.0 10.2 0.11 12.2 0.4 3.7 3 0 0 3 3 3 3 MFS_1 like family DUF1673 PF07895.6 OAJ01590.1 - 0.094 12.2 2.4 0.47 9.9 1.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) AAA PF00004.24 OAJ01592.1 - 1.8e-40 138.2 0.0 3.6e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ01592.1 - 2.8e-07 30.7 0.3 0.00028 20.9 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 OAJ01592.1 - 1.1e-06 28.4 0.1 1.2e-05 25.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ01592.1 - 1.7e-06 28.1 0.2 0.00017 21.7 0.2 2.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ01592.1 - 2.6e-06 26.6 0.0 4.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAJ01592.1 - 1.2e-05 26.1 0.0 2.6e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ01592.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ01592.1 - 6.7e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 OAJ01592.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 OAJ01592.1 - 0.0004 20.3 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 OAJ01592.1 - 0.00043 20.5 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ01592.1 - 0.00081 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 OAJ01592.1 - 0.0021 16.8 0.0 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 OAJ01592.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 OAJ01592.1 - 0.0025 17.9 0.0 0.0063 16.6 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 OAJ01592.1 - 0.0025 17.2 1.9 0.036 13.4 0.4 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 OAJ01592.1 - 0.0028 16.8 0.2 0.0085 15.2 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ01592.1 - 0.0034 17.0 0.5 0.0081 15.8 0.4 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 OAJ01592.1 - 0.0042 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 OAJ01592.1 - 0.0045 16.6 0.0 0.0091 15.6 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_21 PF13304.1 OAJ01592.1 - 0.0073 16.3 0.5 1.9 8.3 0.1 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ01592.1 - 0.0073 15.4 0.1 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF815 PF05673.8 OAJ01592.1 - 0.0089 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 OAJ01592.1 - 0.0093 15.4 0.0 0.019 14.4 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain KaiC PF06745.8 OAJ01592.1 - 0.013 14.6 0.0 0.13 11.3 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.12 OAJ01592.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 OAJ01592.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 OAJ01592.1 - 0.026 14.2 0.6 2 8.0 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 OAJ01592.1 - 0.045 13.3 0.0 0.17 11.5 0.0 1.9 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) S1FA PF04689.8 OAJ01592.1 - 0.057 13.2 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA Guanylate_kin PF00625.16 OAJ01592.1 - 0.085 12.2 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase DUF2075 PF09848.4 OAJ01592.1 - 0.099 11.5 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 OAJ01592.1 - 0.11 12.1 0.3 0.29 10.7 0.1 1.8 2 0 0 2 2 1 0 NACHT domain IPT PF01745.11 OAJ01592.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase ABC_tran PF00005.22 OAJ01592.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 OAJ01592.1 - 0.13 11.9 0.1 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 OAJ01592.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.9 OAJ01592.1 - 0.4 9.6 2.7 2.1 7.2 0.1 2.6 2 1 1 3 3 3 0 KAP family P-loop domain Homeobox_KN PF05920.6 OAJ01593.1 - 3.5e-16 58.6 3.4 7e-16 57.6 2.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 OAJ01593.1 - 9.9e-06 25.0 1.1 2.2e-05 24.0 0.8 1.6 1 0 0 1 1 1 1 Homeobox domain Glyco_hydro_16 PF00722.16 OAJ01594.1 - 2.4e-06 26.9 0.0 6.8e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RhoGEF PF00621.15 OAJ01595.1 - 2.3e-39 135.1 0.0 4.7e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 OAJ01595.1 - 4.2e-17 61.2 0.3 3.7e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 OAJ01595.1 - 3.2e-16 58.9 0.0 8.8e-16 57.5 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_9 PF14604.1 OAJ01595.1 - 6.1e-16 57.7 0.1 1.7e-08 33.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 OAJ01595.1 - 2.7e-10 39.5 0.0 3.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 OAJ01595.1 - 4.9e-06 25.9 0.1 1.2e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 WH2 motif PH PF00169.24 OAJ01595.1 - 0.00027 21.1 0.0 0.00063 19.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Pilin PF00114.14 OAJ01598.1 - 0.01 16.5 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 0 Pilin (bacterial filament) ESSS PF10183.4 OAJ01598.1 - 0.088 13.2 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ESR1_C PF12743.2 OAJ01598.1 - 9 5.9 7.7 1.3 8.6 0.3 2.9 2 1 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal zf-C2HC_2 PF13913.1 OAJ01600.1 - 0.087 12.5 0.2 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Ytp1 PF10355.4 OAJ01601.1 - 2.5e-66 223.6 22.0 2.9e-55 187.3 11.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ01601.1 - 1.8e-24 85.3 2.9 1.8e-24 85.3 2.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Antimicrobial10 PF08105.6 OAJ01601.1 - 0.24 11.0 2.3 0.5 10.0 1.1 1.9 1 1 1 2 2 2 0 Metchnikowin family PBP1_TM PF14812.1 OAJ01601.1 - 7.6 6.9 9.8 4.9 7.5 2.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 OAJ01602.1 - 0.00046 19.6 1.1 0.00068 19.0 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SDA1 PF05285.7 OAJ01602.1 - 0.55 9.4 16.2 0.7 9.1 11.2 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.2 OAJ01602.1 - 0.7 9.3 7.2 1.8 8.0 5.0 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Daxx PF03344.10 OAJ01602.1 - 2.9 6.2 16.3 3.6 5.9 11.3 1.1 1 0 0 1 1 1 0 Daxx Family Spt5_N PF11942.3 OAJ01602.1 - 6.8 7.3 23.2 7.1 7.3 5.8 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal MFS_1 PF07690.11 OAJ01603.1 - 6.9e-29 100.6 33.6 1.8e-28 99.2 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2207 PF09972.4 OAJ01603.1 - 0.42 9.1 9.6 2 6.9 1.1 3.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) PspB PF06667.7 OAJ01603.1 - 1 9.3 3.1 18 5.3 0.3 3.2 3 0 0 3 3 3 0 Phage shock protein B HisG PF01634.13 OAJ01604.1 - 6.4e-42 142.9 0.1 2.3e-41 141.0 0.0 1.9 2 1 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 OAJ01604.1 - 2.5e-23 81.7 0.1 5.2e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain PMI_typeI PF01238.16 OAJ01605.1 - 3.2e-56 190.8 0.0 4.7e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 OAJ01605.1 - 0.082 12.4 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Cupin domain NUFIP1 PF10453.4 OAJ01609.1 - 1.4e-11 43.7 0.3 3.5e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Nop14 PF04147.7 OAJ01609.1 - 0.024 12.6 18.7 0.035 12.0 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family MIT PF04212.13 OAJ01610.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SH3BP5 PF05276.9 OAJ01610.1 - 0.28 10.4 0.0 0.43 9.8 0.0 1.3 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Myosin_head PF00063.16 OAJ01611.1 - 7.1e-224 744.8 3.7 1.2e-223 744.1 2.6 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 OAJ01611.1 - 5.6e-41 140.0 0.0 1.2e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 OAJ01611.1 - 5.6e-12 45.0 0.1 1.6e-11 43.6 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ01611.1 - 9.1e-11 40.9 0.2 1.9e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ01611.1 - 1.4e-08 34.1 0.1 5e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 OAJ01611.1 - 0.0073 16.4 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain SH3_4 PF06347.8 OAJ01611.1 - 0.013 14.9 0.6 0.036 13.6 0.4 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Zeta_toxin PF06414.7 OAJ01611.1 - 0.044 12.8 0.1 0.098 11.7 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 OAJ01611.1 - 0.055 14.2 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 OAJ01611.1 - 0.059 12.6 0.4 5 6.3 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 OAJ01611.1 - 0.14 11.8 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 OAJ01611.1 - 0.22 11.4 0.0 0.62 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.22 OAJ01611.1 - 4.3 7.2 6.7 1.5 8.6 0.9 2.5 1 1 1 2 2 2 0 IQ calmodulin-binding motif DEAD PF00270.24 OAJ01614.1 - 3.7e-16 59.0 0.0 3.4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01614.1 - 4.6e-13 48.8 0.0 1.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01614.1 - 2.4e-07 30.7 0.0 3.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit G-alpha PF00503.15 OAJ01615.1 - 6.8e-83 278.5 0.0 1.3e-54 185.4 0.0 3.1 3 0 0 3 3 3 3 G-protein alpha subunit Arf PF00025.16 OAJ01615.1 - 1.7e-09 37.1 0.0 2.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_30 PF13604.1 OAJ01615.1 - 0.0024 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 OAJ01615.1 - 0.0051 17.2 0.0 0.029 14.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 OAJ01615.1 - 0.013 14.6 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 OAJ01615.1 - 0.027 14.7 0.0 0.07 13.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 OAJ01615.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PLDc_2 PF13091.1 OAJ01616.1 - 4.9e-12 45.6 0.0 6.2e-06 25.9 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 OAJ01616.1 - 1.9e-05 24.3 4.3 0.033 13.9 0.0 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif Ribosomal_60s PF00428.14 OAJ01618.1 - 4.6e-25 87.8 11.4 4.6e-25 87.8 7.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.15 OAJ01618.1 - 3.7e-24 84.5 0.1 1.2e-23 82.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 DUF3224 PF11528.3 OAJ01621.1 - 0.15 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) DPPIV_N PF00930.16 OAJ01622.1 - 1.5e-71 240.8 0.0 1.2e-69 234.5 0.0 2.5 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 OAJ01622.1 - 5.9e-42 143.3 0.5 9.4e-42 142.6 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ01622.1 - 1.1e-05 25.1 0.1 2.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ01622.1 - 3.1e-05 23.9 0.8 7.3e-05 22.7 0.6 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 OAJ01622.1 - 0.00049 19.6 0.7 0.0021 17.5 0.4 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 OAJ01622.1 - 0.065 11.7 0.1 0.32 9.4 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Rad21_Rec8_N PF04825.8 OAJ01629.1 - 1.8e-23 82.5 0.0 3.9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ01629.1 - 2.6e-08 32.9 0.0 7e-08 31.5 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein OmpH PF03938.9 OAJ01629.1 - 0.011 15.7 0.7 0.011 15.7 0.5 2.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Kinocilin PF15033.1 OAJ01630.1 - 0.45 10.0 0.1 0.45 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinocilin protein SOBP PF15279.1 OAJ01630.1 - 1.1 9.5 14.6 1.7 8.9 10.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PIF1 PF05970.9 OAJ01631.1 - 2.7e-96 322.7 0.0 3.5e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ01631.1 - 1.8e-61 207.1 0.0 3.7e-61 206.0 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ01631.1 - 0.00039 18.3 0.0 0.00097 17.0 0.0 1.5 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 OAJ01631.1 - 0.0042 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ01631.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ01631.1 - 0.093 12.4 1.5 0.25 11.1 0.5 2.2 2 0 0 2 2 2 0 Part of AAA domain Transposase_21 PF02992.9 OAJ01632.1 - 4.7e-23 81.4 0.0 8.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 FG-GAP PF01839.18 OAJ01632.1 - 0.013 15.1 0.7 0.044 13.4 0.5 1.9 1 0 0 1 1 1 0 FG-GAP repeat DUF2236 PF09995.4 OAJ01633.1 - 1.3e-22 80.3 0.4 1.3e-22 80.3 0.3 1.5 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Cyclin_N PF00134.18 OAJ01634.1 - 7.1e-12 45.0 1.6 9.9e-12 44.5 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 OAJ01634.1 - 0.00019 21.1 0.5 0.00045 19.9 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Xan_ur_permease PF00860.15 OAJ01637.1 - 2e-49 168.1 32.3 7.3e-48 162.9 22.4 2.1 1 1 0 1 1 1 1 Permease family MFS_1 PF07690.11 OAJ01638.1 - 2.4e-42 144.9 64.9 1e-35 123.1 29.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ01638.1 - 2.9e-14 52.4 34.3 9.7e-11 40.8 7.2 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter Helicase_C_3 PF13625.1 OAJ01639.1 - 2.5e-24 85.4 0.0 6.9e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01639.1 - 1.7e-14 54.0 0.0 2.9e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ01639.1 - 4.9e-12 45.2 0.0 7.7e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ01639.1 - 4.1e-10 39.3 0.1 1.9e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PIF1 PF05970.9 OAJ01641.1 - 8.3e-103 344.1 0.0 1.1e-102 343.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ01641.1 - 2.5e-61 206.5 0.0 4.4e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ01641.1 - 1.9e-05 22.6 0.0 3.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 OAJ01641.1 - 0.0005 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ01641.1 - 0.011 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ01641.1 - 0.037 13.7 0.4 0.13 12.0 0.3 1.9 1 0 0 1 1 1 0 Part of AAA domain Peptidase_S30 PF01577.11 OAJ01642.1 - 0.11 11.9 7.2 0.16 11.3 5.0 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Phage_GPO PF05929.6 OAJ01642.1 - 0.44 9.7 9.0 1.1 8.4 6.2 1.6 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DB PF01682.14 OAJ01644.1 - 0.71 9.9 4.8 5.7 7.0 0.1 2.6 2 1 0 2 2 2 0 DB module MoCF_biosynth PF00994.19 OAJ01649.1 - 9.1e-53 177.5 0.6 7.9e-28 96.6 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 OAJ01649.1 - 2e-29 102.0 1.4 4.5e-29 100.8 1.0 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 OAJ01649.1 - 9.9e-15 54.2 0.1 2.8e-14 52.8 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PyrBI_leader PF08052.6 OAJ01649.1 - 0.15 11.8 0.1 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 PyrBI operon leader peptide NmrA PF05368.8 OAJ01650.1 - 2.2e-16 59.8 0.0 2.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ01650.1 - 0.00028 20.9 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding XPG_N PF00752.12 OAJ01653.1 - 1.4e-34 118.3 0.0 2.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ01653.1 - 6.3e-30 103.0 0.0 1.4e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 OAJ01653.1 - 9.5e-07 28.9 0.0 2.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 OAJ01653.1 - 0.0047 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Transposase_20 PF02371.11 OAJ01653.1 - 0.035 14.2 1.4 0.12 12.5 0.0 2.5 3 0 0 3 3 3 0 Transposase IS116/IS110/IS902 family Fe_dep_repr_C PF02742.10 OAJ01653.1 - 0.066 12.9 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain HHH PF00633.18 OAJ01653.1 - 0.068 12.9 0.3 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4192 PF13830.1 OAJ01653.1 - 0.086 12.4 0.7 0.28 10.7 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Coatomer_WDAD PF04053.9 OAJ01655.1 - 1.4e-30 106.4 0.2 1.8e-15 56.7 0.0 3.0 3 0 0 3 3 3 3 Coatomer WD associated region DUF508 PF04370.7 OAJ01657.1 - 0.017 14.7 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ipi1_N PF12333.3 OAJ01657.1 - 0.036 14.0 0.1 0.17 11.8 0.0 1.9 1 1 1 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation HTH_28 PF13518.1 OAJ01659.1 - 5.7e-05 23.0 0.1 0.00019 21.3 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 OAJ01659.1 - 0.00067 19.2 0.0 0.0032 17.0 0.0 2.2 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.8 OAJ01659.1 - 0.0052 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_17 PF12728.2 OAJ01659.1 - 0.02 15.1 0.1 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.1 OAJ01659.1 - 0.027 14.7 0.0 0.5 10.7 0.0 3.0 2 0 0 2 2 2 0 leucine-zipper of insertion element IS481 Phage_terminase PF10668.4 OAJ01659.1 - 0.034 13.9 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 Phage terminase small subunit HTH_Tnp_IS630 PF01710.11 OAJ01659.1 - 0.065 12.8 0.3 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Transposase Hemocyanin_C PF03723.9 OAJ01659.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Hemocyanin, ig-like domain P22_Cro PF14549.1 OAJ01659.1 - 0.08 12.6 0.1 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro HTH_Tnp_1 PF01527.15 OAJ01659.1 - 0.11 12.4 0.9 0.38 10.7 0.2 2.2 2 0 0 2 2 2 0 Transposase Metallophos PF00149.23 OAJ01660.1 - 1.4e-11 44.2 0.1 4.6e-11 42.4 0.1 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ01660.1 - 0.00016 21.5 0.0 0.001 18.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Luteo_coat PF00894.13 OAJ01660.1 - 0.033 13.9 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Luteovirus coat protein GlgS PF08971.6 OAJ01660.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein Rav1p_C PF12234.3 OAJ01661.1 - 1.1e-88 298.0 0.0 1.5e-88 297.6 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal Oxidored_FMN PF00724.15 OAJ01662.1 - 8.9e-58 195.8 0.0 1.2e-57 195.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DnaJ PF00226.26 OAJ01664.1 - 8.1e-17 60.7 0.1 1.9e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Pro_CA PF00484.14 OAJ01665.1 - 4.3e-23 82.0 0.0 5.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase adh_short PF00106.20 OAJ01666.1 - 9.8e-16 58.1 2.5 6.8e-14 52.1 1.7 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ01666.1 - 7e-06 25.8 0.7 3.9e-05 23.3 0.5 2.2 1 1 0 1 1 1 1 KR domain ADH_N PF08240.7 OAJ01668.1 - 4.4e-22 77.8 1.6 9.5e-22 76.8 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ01668.1 - 7.6e-15 54.6 0.1 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 OAJ01668.1 - 2.1e-05 24.6 0.0 0.00049 20.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ01668.1 - 3.1e-05 23.1 0.1 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ01668.1 - 0.0027 17.3 0.1 0.0051 16.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 OAJ01668.1 - 0.0033 17.7 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_2 PF03446.10 OAJ01668.1 - 0.0058 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 OAJ01668.1 - 0.035 14.6 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.16 OAJ01668.1 - 0.037 13.5 1.5 0.061 12.8 0.1 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 OAJ01668.1 - 0.14 11.9 1.8 0.31 10.8 1.2 1.5 1 0 0 1 1 1 0 ThiF family Lipase_3 PF01764.20 OAJ01669.1 - 1.4e-23 83.0 0.0 2.9e-23 82.0 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 OAJ01669.1 - 0.014 15.2 0.4 0.025 14.4 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ01669.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ01669.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.3 OAJ01669.1 - 0.082 12.2 0.1 0.94 8.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2756 PF10956.3 OAJ01669.1 - 0.17 12.1 0.2 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) DUF1777 PF08648.7 OAJ01670.1 - 0.0038 17.0 40.0 0.0046 16.7 27.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) Raftlin PF15250.1 OAJ01670.1 - 0.55 8.6 4.3 0.9 7.9 2.8 1.6 1 1 0 1 1 1 0 Raftlin PLRV_ORF5 PF01690.12 OAJ01670.1 - 2.8 6.9 6.6 3.3 6.7 4.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 OAJ01670.1 - 8.1 4.9 6.2 9.2 4.7 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0564 PF10595.4 OAJ01671.1 - 0.53 9.1 48.8 0.73 8.6 33.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 OPT PF03169.10 OAJ01677.1 - 5.9e-187 622.9 54.2 6.8e-187 622.6 37.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NicO PF03824.11 OAJ01678.1 - 1.5e-21 76.9 19.1 1e-07 31.5 0.1 5.3 4 2 1 5 5 5 3 High-affinity nickel-transport protein DUF1115 PF06544.7 OAJ01678.1 - 6.1e-05 22.7 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PDGLE PF13190.1 OAJ01678.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 PDGLE domain zf-DHHC PF01529.15 OAJ01679.1 - 6.3e-39 133.1 12.2 6.3e-39 133.1 8.4 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.2 OAJ01679.1 - 0.042 13.6 3.1 0.097 12.5 2.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Spt4 PF06093.8 OAJ01679.1 - 0.47 10.3 2.2 2.5 8.0 1.8 1.9 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Skp1_POZ PF03931.10 OAJ01680.1 - 8.1e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain CHCH PF06747.8 OAJ01681.1 - 2.9e-06 27.0 0.8 3.9e-06 26.6 0.6 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 OAJ01681.1 - 0.0002 21.0 0.6 0.00024 20.7 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 OAJ01681.1 - 0.18 11.9 0.5 0.32 11.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Calcipressin PF04847.7 OAJ01682.1 - 7.7e-26 90.8 0.0 1.2e-23 83.6 0.0 2.3 1 1 0 1 1 1 1 Calcipressin Voldacs PF03517.8 OAJ01682.1 - 1.3e-25 89.8 0.0 1.3e-25 89.8 0.0 2.0 3 0 0 3 3 3 1 Regulator of volume decrease after cellular swelling GRAM PF02893.15 OAJ01682.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Septin PF00735.13 OAJ01683.1 - 7.7e-76 254.7 0.3 1.1e-75 254.2 0.2 1.2 1 0 0 1 1 1 1 Septin Cep57_CLD_2 PF14197.1 OAJ01683.1 - 3.8 7.5 10.0 1.6 8.7 0.5 2.6 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Septin PF00735.13 OAJ01684.1 - 1.5e-24 86.5 0.1 1.8e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 OAJ01684.1 - 9.8e-09 34.5 0.0 1.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 OAJ01684.1 - 3.2e-08 33.5 0.1 4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ01684.1 - 4.1e-06 26.3 0.1 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.17 OAJ01684.1 - 4.6e-06 26.1 0.6 1.1e-05 24.8 0.4 1.6 1 1 0 1 1 1 1 Ras family AAA_10 PF12846.2 OAJ01684.1 - 6.8e-05 22.4 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 OAJ01684.1 - 0.0001 21.5 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 OAJ01684.1 - 0.00012 22.5 0.2 0.00015 22.1 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 OAJ01684.1 - 0.00013 21.5 0.2 0.00017 21.2 0.1 1.1 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 OAJ01684.1 - 0.00028 20.7 1.3 0.041 13.7 0.2 2.1 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 OAJ01684.1 - 0.00048 20.4 0.0 0.00058 20.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 OAJ01684.1 - 0.0005 20.2 0.1 0.00069 19.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 OAJ01684.1 - 0.00051 19.2 0.0 0.00065 18.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAJ01684.1 - 0.00051 19.5 1.3 0.0018 17.7 0.3 1.9 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 OAJ01684.1 - 0.00083 19.3 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 OAJ01684.1 - 0.00094 18.9 0.7 0.0015 18.2 0.4 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 OAJ01684.1 - 0.0014 17.9 0.2 0.004 16.4 0.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B NACHT PF05729.7 OAJ01684.1 - 0.0027 17.3 0.1 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 OAJ01684.1 - 0.0033 16.9 0.1 0.0043 16.5 0.1 1.3 1 1 0 1 1 1 1 Sigma-54 interaction domain ATP_bind_1 PF03029.12 OAJ01684.1 - 0.0063 16.0 0.8 0.4 10.1 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 OAJ01684.1 - 0.0067 15.9 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 OAJ01684.1 - 0.0072 15.5 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 OAJ01684.1 - 0.0074 15.7 0.1 0.009 15.5 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family SRPRB PF09439.5 OAJ01684.1 - 0.0077 15.4 0.1 0.011 15.0 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 OAJ01684.1 - 0.0088 15.9 0.1 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAJ01684.1 - 0.012 14.7 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 OAJ01684.1 - 0.012 14.9 0.3 0.017 14.4 0.1 1.4 1 1 0 1 1 1 0 Poxvirus A32 protein T2SE PF00437.15 OAJ01684.1 - 0.013 14.4 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ01684.1 - 0.015 15.2 0.1 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ01684.1 - 0.015 15.4 0.1 0.037 14.2 0.0 1.6 1 1 1 2 2 2 0 RNA helicase NB-ARC PF00931.17 OAJ01684.1 - 0.016 14.0 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 OAJ01684.1 - 0.028 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 OAJ01684.1 - 0.03 14.6 0.1 0.039 14.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ01684.1 - 0.033 13.5 0.3 0.062 12.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ01684.1 - 0.036 14.0 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ01684.1 - 0.038 14.3 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 OAJ01684.1 - 0.042 12.6 0.4 0.067 11.9 0.2 1.4 1 1 0 1 1 1 0 ArgK protein IIGP PF05049.8 OAJ01684.1 - 0.047 12.5 0.3 0.057 12.2 0.2 1.3 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF3914 PF13053.1 OAJ01684.1 - 0.048 13.8 0.1 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Viral_helicase1 PF01443.13 OAJ01684.1 - 0.057 12.9 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RHD3 PF05879.7 OAJ01684.1 - 0.059 11.2 0.0 0.062 11.2 0.0 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) cobW PF02492.14 OAJ01684.1 - 0.059 12.8 0.9 0.082 12.3 0.5 1.4 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 OAJ01684.1 - 0.089 12.5 0.9 0.14 11.8 0.6 1.6 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.9 OAJ01684.1 - 0.1 12.3 0.2 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 OAJ01684.1 - 0.12 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 OAJ01684.1 - 0.13 12.4 0.2 0.19 11.9 0.1 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 OAJ01684.1 - 0.14 11.5 2.8 0.75 9.2 2.2 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Phage_Nu1 PF07471.7 OAJ01685.1 - 0.16 11.4 8.7 0.31 10.4 6.0 1.4 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Y_phosphatase3 PF13350.1 OAJ01685.1 - 1.4 9.1 4.7 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family TFIIS_C PF01096.13 OAJ01686.1 - 6.8e-19 67.2 4.0 6.8e-19 67.2 2.7 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 OAJ01686.1 - 5.1e-08 32.4 2.4 2.1e-06 27.2 0.3 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 OAJ01686.1 - 0.00019 21.1 7.9 0.0038 17.0 0.7 2.6 2 1 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 OAJ01686.1 - 0.00099 18.8 5.6 0.57 10.0 0.1 3.4 3 1 0 3 3 3 2 PhnA Zinc-Ribbon Desulfoferrod_N PF06397.7 OAJ01686.1 - 0.0056 16.0 1.6 0.04 13.3 0.1 2.3 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain Nudix_N_2 PF14803.1 OAJ01686.1 - 0.025 14.2 0.7 0.025 14.2 0.5 3.3 3 0 0 3 3 3 0 Nudix N-terminal RNHCP PF12647.2 OAJ01686.1 - 0.027 14.2 5.8 0.37 10.6 0.1 2.4 2 1 0 2 2 2 0 RNHCP domain TF_Zn_Ribbon PF08271.7 OAJ01686.1 - 0.032 13.5 5.1 0.37 10.1 0.8 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Opy2 PF09463.5 OAJ01686.1 - 0.042 13.9 3.9 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 Opy2 protein Tnp_zf-ribbon_2 PF13842.1 OAJ01686.1 - 0.043 14.2 2.7 4.4 7.8 0.0 2.7 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.2 OAJ01686.1 - 0.077 12.8 7.9 0.095 12.5 0.4 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-DNA_Pol PF08996.5 OAJ01686.1 - 0.081 12.2 3.3 0.23 10.7 0.7 2.0 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-RING_3 PF14369.1 OAJ01686.1 - 0.093 12.7 0.8 0.093 12.7 0.6 2.7 3 0 0 3 3 3 0 zinc-finger tRNA-synt_1b PF00579.20 OAJ01686.1 - 0.15 11.1 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) HypA PF01155.14 OAJ01686.1 - 0.25 11.0 4.0 14 5.3 2.8 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn_ribbon_recom PF13408.1 OAJ01686.1 - 0.43 10.8 0.1 0.43 10.8 0.1 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 OAJ01686.1 - 0.43 10.1 5.1 22 4.6 0.3 3.4 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Zn-ribbon_8 PF09723.5 OAJ01686.1 - 0.57 10.1 8.8 1.6 8.7 0.2 2.9 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 OAJ01686.1 - 0.96 9.2 0.0 0.96 9.2 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain TerY-C PF15616.1 OAJ01686.1 - 1 9.3 5.4 5 7.0 0.7 2.2 1 1 0 2 2 2 0 TerY-C metal binding domain zinc_ribbon_5 PF13719.1 OAJ01686.1 - 1.1 8.8 0.0 1.1 8.8 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 OAJ01686.1 - 1.6 8.4 6.9 5.1 6.8 0.6 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 OAJ01686.1 - 1.7 7.9 10.3 32 3.8 0.1 3.3 2 1 0 2 2 2 0 zinc-ribbon domain zf-CHY PF05495.7 OAJ01686.1 - 2.7 8.2 7.7 1.3 9.2 0.3 2.5 2 1 0 2 2 2 0 CHY zinc finger C1_1 PF00130.17 OAJ01686.1 - 3.8 7.3 9.1 0.57 9.9 0.5 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3797 PF12677.2 OAJ01686.1 - 5.1 6.8 6.7 4.2 7.0 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zf-Sec23_Sec24 PF04810.10 OAJ01686.1 - 5.2 6.7 6.5 5.8 6.5 2.1 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger NOB1_Zn_bind PF08772.6 OAJ01686.1 - 6.1 6.7 9.4 4.9 7.0 0.3 2.7 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like OrfB_Zn_ribbon PF07282.6 OAJ01686.1 - 7.8 6.2 8.4 1.5 8.5 0.3 2.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Pkinase_Tyr PF07714.12 OAJ01687.1 - 2.8e-06 26.5 0.0 0.00065 18.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ01687.1 - 4.4e-06 26.0 0.0 0.0007 18.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain YGGT PF02325.12 OAJ01687.1 - 0.094 12.6 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 YGGT family Pkinase PF00069.20 OAJ01688.1 - 3.8e-53 180.3 0.0 5.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01688.1 - 8.6e-42 142.9 0.0 1.2e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01688.1 - 0.014 14.3 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 OAJ01688.1 - 0.028 14.1 1.4 0.067 12.9 0.7 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ01688.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LAP1C PF05609.7 OAJ01688.1 - 3.2 6.3 7.8 5.8 5.4 5.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1768 PF08719.6 OAJ01689.1 - 9.8e-25 87.1 0.1 1.4e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Clat_adaptor_s PF01217.15 OAJ01689.1 - 0.021 14.5 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain LtrA PF06772.6 OAJ01691.1 - 2e-16 59.8 24.9 9.6e-09 34.6 0.3 2.7 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Glyco_hydro_92 PF07971.7 OAJ01692.1 - 2.5e-106 356.3 0.0 3.6e-106 355.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1769 PF08588.5 OAJ01693.1 - 1.3e-20 73.0 0.1 2.3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cys_Met_Meta_PP PF01053.15 OAJ01694.1 - 3.8e-25 87.9 0.0 1.2e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAJ01694.1 - 0.00036 19.5 0.0 0.00074 18.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Cid2 PF09774.4 OAJ01702.1 - 3.5e-24 85.6 0.4 8.1e-23 81.2 0.3 2.1 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Abhydrolase_6 PF12697.2 OAJ01704.1 - 7.5e-27 94.6 0.0 1e-26 94.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ01704.1 - 3e-17 62.9 0.0 2e-11 43.9 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ01704.1 - 6.1e-11 42.2 0.0 9.7e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ01704.1 - 0.001 18.5 0.0 0.0014 18.0 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 OAJ01704.1 - 0.0053 16.2 0.2 0.6 9.5 0.1 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.15 OAJ01704.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 OAJ01704.1 - 0.023 14.3 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.13 OAJ01704.1 - 0.12 11.6 0.1 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.4 OAJ01704.1 - 0.23 10.2 1.1 3.8 6.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Response_reg PF00072.19 OAJ01706.1 - 3e-25 88.3 0.1 6.4e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ01706.1 - 2.7e-18 65.7 0.0 4.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ01706.1 - 1.3e-09 37.8 0.4 7e-09 35.5 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF848 PF05852.6 OAJ01706.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) GAF_3 PF13492.1 OAJ01706.1 - 0.054 13.6 0.3 0.48 10.5 0.1 2.7 2 1 0 2 2 2 0 GAF domain Metallophos PF00149.23 OAJ01707.1 - 8.3e-06 25.3 4.9 5.5e-05 22.6 3.4 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PI3K_1B_p101 PF10486.4 OAJ01707.1 - 0.0038 14.8 0.3 0.0052 14.4 0.2 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spt5_N PF11942.3 OAJ01707.1 - 0.17 12.4 9.3 0.63 10.6 6.5 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Tom37_C PF11801.3 OAJ01707.1 - 1.3 8.8 4.1 3.1 7.6 2.9 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC45 PF02724.9 OAJ01707.1 - 2 6.3 6.5 3.1 5.7 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Tubulin PF00091.20 OAJ01709.1 - 1.9e-69 233.8 0.0 2.6e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ01709.1 - 7.8e-45 151.9 0.0 1.2e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 OAJ01709.1 - 0.0004 19.9 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 OAJ01709.1 - 0.035 13.7 0.1 0.68 9.5 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) Mito_carr PF00153.22 OAJ01710.1 - 1.3e-62 207.5 9.0 2.7e-23 81.4 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 OAJ01710.1 - 2.8e-05 23.1 0.2 0.00034 19.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 OAJ01710.1 - 0.00032 20.3 0.1 0.0041 16.8 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 OAJ01710.1 - 0.00045 19.4 0.4 0.0015 17.7 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 OAJ01710.1 - 0.0015 18.6 0.5 0.0043 17.1 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair PHD PF00628.24 OAJ01711.1 - 1.8e-08 33.9 8.9 3.6e-08 32.9 6.2 1.5 1 0 0 1 1 1 1 PHD-finger Flavokinase PF01687.12 OAJ01712.1 - 2.8e-34 117.6 0.0 4.2e-34 117.1 0.0 1.3 1 1 0 1 1 1 1 Riboflavin kinase TPR_11 PF13414.1 OAJ01713.1 - 2e-11 43.3 4.4 5.9e-10 38.6 1.3 2.7 2 0 0 2 2 2 1 TPR repeat DnaJ PF00226.26 OAJ01713.1 - 2.1e-06 27.3 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 OAJ01713.1 - 0.00038 19.9 1.0 0.0019 17.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ01713.1 - 0.00082 19.1 6.7 0.044 13.7 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01713.1 - 0.11 12.4 2.1 0.4 10.6 1.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat rve PF00665.21 OAJ01714.1 - 1.4e-05 25.1 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 OAJ01714.1 - 0.00013 21.5 1.6 0.00053 19.5 0.0 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_11 PF08279.7 OAJ01714.1 - 0.0081 15.7 0.4 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 HTH domain HTH_Crp_2 PF13545.1 OAJ01714.1 - 0.012 15.3 0.1 0.12 12.1 0.0 2.5 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain COG2 PF06148.6 OAJ01714.1 - 0.032 14.1 0.2 0.08 12.8 0.1 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HTH_17 PF12728.2 OAJ01714.1 - 0.078 13.2 0.3 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain CPSase_L_D3 PF02787.14 OAJ01714.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Phosducin PF02114.11 OAJ01715.1 - 2.1e-09 36.5 0.4 2.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Phosducin GOLD_2 PF13897.1 OAJ01715.1 - 0.062 13.5 1.3 0.16 12.1 0.9 1.7 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Apc9 PF12856.2 OAJ01715.1 - 2.1 8.4 8.8 0.16 12.0 2.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 Cwf_Cwc_15 PF04889.7 OAJ01715.1 - 2.9 7.5 19.0 0.2 11.3 8.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 OAJ01715.1 - 4.1 6.9 14.5 0.48 10.0 5.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region YL1 PF05764.8 OAJ01715.1 - 4.7 6.7 13.7 0.57 9.7 6.7 1.5 2 0 0 2 2 2 0 YL1 nuclear protein Ferric_reduct PF01794.14 OAJ01716.1 - 1.9e-22 79.7 16.5 2.2e-22 79.4 9.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ01716.1 - 4.1e-20 72.2 0.0 5.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ01716.1 - 8.4e-10 38.4 0.1 4.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ01716.1 - 0.01 16.3 0.0 0.11 13.1 0.0 2.3 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain Fork_head PF00250.13 OAJ01717.1 - 7.6e-30 102.8 0.0 1.5e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain MULE PF10551.4 OAJ01718.1 - 2.2e-14 53.4 0.1 5.7e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ01718.1 - 5e-08 31.9 0.0 8.8e-08 31.0 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.10 OAJ01718.1 - 1.4e-06 28.7 1.5 3.9e-06 27.2 1.0 1.8 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.12 OAJ01718.1 - 0.002 17.5 0.2 0.0065 15.9 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.1 OAJ01718.1 - 0.027 14.4 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 DDE domain Peptidase_C48 PF02902.14 OAJ01718.1 - 0.044 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DDE_Tnp_ISL3 PF01610.12 OAJ01718.1 - 0.06 12.9 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Transposase DUF1722 PF08349.6 OAJ01718.1 - 0.11 12.3 0.0 0.75 9.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Glycos_transf_1 PF00534.15 OAJ01719.1 - 1.5e-14 53.8 0.0 5.3e-14 52.0 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 OAJ01719.1 - 9.6e-07 29.0 0.0 9.2e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 RVT_2 PF07727.9 OAJ01720.1 - 3.2e-75 252.2 0.0 5.8e-75 251.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01720.1 - 3.6e-17 62.5 0.0 2.8e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ01720.1 - 4.5e-15 55.2 0.0 7.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ01720.1 - 7.6e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ01720.1 - 6.9e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ01720.1 - 0.0041 16.9 6.1 0.0087 15.9 4.3 1.6 1 0 0 1 1 1 1 Zinc knuckle DUF4219 PF13961.1 OAJ01720.1 - 0.012 15.0 0.4 0.029 13.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) RVT_3 PF13456.1 OAJ01720.1 - 0.049 13.4 0.0 1.1 9.0 0.0 3.0 3 0 0 3 3 3 0 Reverse transcriptase-like RVP PF00077.15 OAJ01720.1 - 0.11 12.4 0.1 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Retroviral aspartyl protease rve_3 PF13683.1 OAJ01720.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain PLA2_B PF01735.13 OAJ01725.1 - 6.6e-138 459.9 2.1 7.9e-138 459.6 1.5 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Hom_end_hint PF05203.11 OAJ01726.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Peptidase_M18 PF02127.10 OAJ01727.1 - 5.7e-154 512.7 0.0 6.6e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 OAJ01727.1 - 0.00022 20.1 0.0 0.045 12.5 0.0 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.18 OAJ01728.1 - 6.4e-19 68.8 0.3 9.7e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 OAJ01730.1 - 7.5e-43 146.2 0.9 9.5e-43 145.9 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NDUF_B8 PF05821.6 OAJ01731.1 - 4e-11 42.8 0.0 6.3e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) PIP5K PF01504.13 OAJ01732.1 - 3.8e-63 212.9 0.0 3.8e-63 212.9 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 OAJ01732.1 - 5.5e-25 87.9 0.1 8.8e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 OAJ01732.1 - 9.6e-16 57.4 8.4 9.6e-16 57.4 5.8 1.8 2 0 0 2 2 2 1 FYVE zinc finger PHP PF02811.14 OAJ01733.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 PHP domain XPG_I PF00867.13 OAJ01734.1 - 8.4e-27 93.0 0.0 2.2e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region bZIP_1 PF00170.16 OAJ01734.1 - 1.1e-08 34.8 5.3 1.1e-08 34.8 3.6 4.2 3 1 1 4 4 4 1 bZIP transcription factor DUF3425 PF11905.3 OAJ01734.1 - 7.4e-08 32.3 2.1 7.4e-08 32.3 1.4 3.4 2 2 1 3 3 3 1 Domain of unknown function (DUF3425) Spore_coat_CotO PF14153.1 OAJ01734.1 - 0.00059 19.3 13.8 0.00059 19.3 9.6 4.7 5 0 0 5 5 5 1 Spore coat protein CotO zf-DHHC PF01529.15 OAJ01734.1 - 0.35 10.2 6.9 0.31 10.3 3.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mem_trans PF03547.13 OAJ01734.1 - 6.5 4.9 7.7 0.3 9.3 0.8 1.9 2 0 0 2 2 2 0 Membrane transport protein Otopetrin PF03189.8 OAJ01734.1 - 7.6 5.4 5.6 15 4.4 3.9 1.4 1 0 0 1 1 1 0 Otopetrin WD40 PF00400.27 OAJ01735.1 - 1e-09 37.8 8.2 0.00015 21.4 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Na_H_Exchanger PF00999.16 OAJ01736.1 - 8.6e-25 87.0 36.5 2.2e-16 59.3 5.3 3.9 3 1 0 3 3 3 3 Sodium/hydrogen exchanger family Fst_toxin PF13955.1 OAJ01736.1 - 0.079 12.6 0.3 0.079 12.6 0.2 4.3 6 0 0 6 6 6 0 Toxin Fst, type I toxin-antitoxin system RRM_6 PF14259.1 OAJ01737.1 - 3.6e-07 30.0 0.0 5.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ01737.1 - 0.00067 19.2 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ01737.1 - 0.037 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29 PF00831.18 OAJ01738.1 - 1.8e-19 69.1 3.6 1.8e-19 69.1 2.5 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 OAJ01738.1 - 0.032 14.4 3.2 0.043 14.0 2.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 HTH_12 PF08461.5 OAJ01738.1 - 0.1 12.3 1.1 0.29 10.9 0.2 2.2 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain MRP-L47 PF06984.8 OAJ01738.1 - 0.87 9.5 3.8 1 9.3 0.7 2.4 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF607 PF04678.8 OAJ01738.1 - 0.9 9.4 4.9 1.7 8.5 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF896 PF05979.7 OAJ01738.1 - 2.7 7.6 8.3 0.11 12.1 0.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF896) LIP PF03583.9 OAJ01739.1 - 5.3e-54 183.3 0.2 7.4e-54 182.9 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ01739.1 - 5.8e-08 32.6 0.1 1.2e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ01739.1 - 5.6e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ01739.1 - 0.0008 18.6 0.6 0.069 12.3 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ01739.1 - 0.02 14.6 0.1 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase bZIP_1 PF00170.16 OAJ01740.1 - 2.7e-08 33.6 8.0 2.7e-08 33.6 5.5 3.3 2 1 2 4 4 4 3 bZIP transcription factor Hap4_Hap_bind PF10297.4 OAJ01740.1 - 7.9e-07 28.7 5.1 7.9e-07 28.7 3.5 3.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 OAJ01740.1 - 0.0061 16.3 5.4 0.0061 16.3 3.8 3.7 3 1 1 4 4 4 2 Basic region leucine zipper HALZ PF02183.13 OAJ01740.1 - 0.0062 16.2 0.8 0.013 15.1 0.6 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 OAJ01740.1 - 0.31 10.8 8.2 0.049 13.4 1.9 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 OAJ01740.1 - 4.9 6.7 7.4 0.65 9.5 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 OAJ01740.1 - 9.9 4.9 10.5 19 4.0 7.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 OAJ01740.1 - 10 3.8 4.5 14 3.3 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNF2_N PF00176.18 OAJ01741.1 - 7.4e-72 241.6 2.7 1.2e-71 240.9 1.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 OAJ01741.1 - 6.6e-53 178.5 21.6 6.6e-53 178.5 15.0 3.1 5 0 0 5 5 5 1 DNA-binding domain Helicase_C PF00271.26 OAJ01741.1 - 7.4e-13 48.1 0.0 1.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01741.1 - 1.4e-05 25.0 0.1 0.0001 22.2 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 OAJ01741.1 - 2.5e-05 23.2 2.4 0.00019 20.3 0.0 2.7 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DUF4203 PF13886.1 OAJ01745.1 - 2.6e-29 102.1 20.1 3.9e-29 101.6 14.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Met_10 PF02475.11 OAJ01745.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Pox_A14 PF05767.7 OAJ01745.1 - 0.11 12.4 2.6 0.32 10.9 1.8 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 zf-CCCH PF00642.19 OAJ01747.1 - 2.3e-07 30.3 1.9 3.9e-07 29.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 OAJ01747.1 - 0.18 12.0 185.4 0.2 11.9 27.7 6.1 1 1 3 4 4 4 0 Nucleoporin FG repeat region zf-CCCH_2 PF14608.1 OAJ01747.1 - 0.19 11.7 4.0 0.54 10.3 2.8 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF4510 PF14971.1 OAJ01748.1 - 0.013 15.6 1.2 0.022 14.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Hex_IIIa PF02455.11 OAJ01749.1 - 9.8 4.7 7.8 12 4.4 5.4 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Cellulase PF00150.13 OAJ01750.1 - 5.5e-13 48.7 0.1 1.9e-12 46.9 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rib_5-P_isom_A PF06026.9 OAJ01751.1 - 3.4e-54 182.7 0.0 5.2e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 OAJ01751.1 - 0.025 14.2 0.1 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain ABC_membrane PF00664.18 OAJ01752.1 - 2.1e-79 266.8 19.4 1.1e-46 159.4 2.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ01752.1 - 1.5e-49 167.7 0.0 2e-30 105.8 0.1 2.9 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ01752.1 - 2.3e-06 26.9 0.0 0.0052 16.0 0.0 3.7 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ01752.1 - 4e-05 23.6 0.6 0.051 13.5 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 OAJ01752.1 - 0.00026 20.9 0.2 0.33 10.8 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 OAJ01752.1 - 0.0017 17.8 0.5 2.3 7.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 OAJ01752.1 - 0.0031 17.3 0.4 0.48 10.2 0.0 2.8 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 OAJ01752.1 - 0.0032 17.3 3.3 0.2 11.4 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 T2SE PF00437.15 OAJ01752.1 - 0.0038 16.1 0.0 0.36 9.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 OAJ01752.1 - 0.0041 16.3 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ01752.1 - 0.006 16.0 0.1 3.9 6.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ01752.1 - 0.017 15.1 0.1 5.2 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 OAJ01752.1 - 0.022 14.3 0.6 8.7 5.8 0.2 3.3 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 OAJ01752.1 - 0.025 15.0 2.0 5.4 7.5 0.1 3.2 4 0 0 4 4 2 0 Miro-like protein ABC_ATPase PF09818.4 OAJ01752.1 - 0.21 10.1 0.5 1.2 7.5 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class V-SNARE_C PF12352.3 OAJ01753.1 - 4.7e-17 61.8 4.0 9.2e-17 60.8 2.8 1.5 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ01753.1 - 0.00025 20.6 0.1 0.00067 19.3 0.0 1.7 1 0 0 1 1 1 1 Sec20 HDV_ag PF01517.13 OAJ01753.1 - 0.0041 16.8 0.1 0.0063 16.2 0.1 1.4 1 1 0 1 1 1 1 Hepatitis delta virus delta antigen BCDHK_Adom3 PF10436.4 OAJ01754.1 - 2.4e-37 127.9 0.0 3.5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ01754.1 - 4.3e-14 52.1 0.1 2.6e-08 33.5 0.0 3.5 3 0 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ01754.1 - 1.8e-05 24.4 0.0 4.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C2H2 PF00096.21 OAJ01755.1 - 7.2e-06 26.0 8.3 0.0021 18.2 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ01755.1 - 0.00049 20.2 6.3 0.025 14.8 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ01755.1 - 0.0054 16.5 5.8 0.31 10.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ01755.1 - 0.01 16.0 4.8 0.095 13.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 OAJ01756.1 - 1.8e-73 246.8 0.0 2.3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01756.1 - 7.3e-41 139.9 0.0 1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01756.1 - 1.7e-06 27.2 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ01756.1 - 2.4e-06 26.7 0.1 5.2e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 OAJ01756.1 - 2.8e-05 23.5 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 OAJ01756.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PP1c_bdg PF10488.4 OAJ01756.1 - 0.027 13.6 1.9 0.042 13.0 1.3 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region EcKinase PF02958.15 OAJ01756.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pox_ser-thr_kin PF05445.6 OAJ01756.1 - 0.1 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 OAJ01756.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UBN2_2 PF14227.1 OAJ01757.1 - 2.3e-12 46.5 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ01757.1 - 7.7e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ01757.1 - 1.5e-06 27.8 1.0 1.5e-06 27.8 0.7 2.0 2 0 0 2 2 2 1 Zinc knuckle Pkinase PF00069.20 OAJ01758.1 - 5.6e-72 242.0 0.0 7.1e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01758.1 - 8.6e-30 103.6 0.0 1.4e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01758.1 - 2.9e-05 23.2 0.0 0.00012 21.1 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ01758.1 - 0.00025 20.1 0.2 0.00053 19.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ01758.1 - 0.013 15.2 0.2 0.97 9.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ01758.1 - 0.021 14.1 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 RIO1 family AdoHcyase_NAD PF00670.16 OAJ01758.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_S8 PF00082.17 OAJ01759.1 - 1.2e-55 188.6 3.0 1.8e-55 188.1 2.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 OAJ01759.1 - 1.5e-27 95.2 0.2 3e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain RNA_pol_Rpb2_6 PF00562.23 OAJ01762.1 - 4.2e-104 348.3 0.1 8.6e-101 337.4 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ01762.1 - 1.6e-30 105.5 0.0 2.4e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 OAJ01762.1 - 2.9e-23 81.4 0.0 7.2e-23 80.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 OAJ01762.1 - 5.5e-23 80.6 0.1 1.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 OAJ01762.1 - 1.1e-19 70.6 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ01762.1 - 4e-16 59.0 0.2 2.1e-14 53.5 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 Usp PF00582.21 OAJ01763.1 - 0.22 11.6 2.5 18 5.5 0.1 3.2 2 1 1 3 3 3 0 Universal stress protein family Corona_nucleoca PF00937.13 OAJ01763.1 - 4.5 6.1 29.7 0.014 14.3 2.0 3.4 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein Zip PF02535.17 OAJ01764.1 - 2.2e-51 174.7 9.4 2.6e-51 174.5 6.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter YchF-GTPase_C PF06071.8 OAJ01765.1 - 6.2e-35 118.8 0.1 1.6e-34 117.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 OAJ01765.1 - 2.4e-14 53.2 0.0 1.3e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ01765.1 - 9.2e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 OAJ01765.1 - 0.099 12.0 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 Nucleoplasmin PF03066.10 OAJ01771.1 - 0.0016 17.9 15.1 0.036 13.5 0.1 2.2 2 0 0 2 2 2 2 Nucleoplasmin Voldacs PF03517.8 OAJ01771.1 - 4.9 7.0 9.5 12 5.7 0.4 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Abhydrolase_3 PF07859.8 OAJ01772.1 - 1.4e-19 70.5 0.1 1.2e-18 67.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ01772.1 - 6.6e-11 42.1 0.0 9.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ01772.1 - 3e-09 36.4 0.0 0.00037 19.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 OAJ01772.1 - 3.9e-06 26.9 0.2 5.7e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 OAJ01772.1 - 4e-05 22.5 0.0 0.00016 20.5 0.0 1.7 2 0 0 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.4 OAJ01772.1 - 0.012 14.8 0.5 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 OAJ01772.1 - 0.019 14.4 0.1 1.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase PF00756.15 OAJ01772.1 - 0.026 13.9 0.1 1.2 8.5 0.0 2.7 3 0 0 3 3 3 0 Putative esterase Pkinase_Tyr PF07714.12 OAJ01773.1 - 4.2e-05 22.7 0.0 0.025 13.6 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 OAJ01773.1 - 0.00051 19.2 0.0 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RVT_2 PF07727.9 OAJ01775.1 - 1.9e-87 292.3 0.0 2.7e-87 291.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01775.1 - 3e-24 85.4 0.1 7.5e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ01775.1 - 2.5e-06 27.0 0.3 5.3e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ01775.1 - 2.5e-05 23.6 0.0 9.6e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAJ01776.1 - 0.00032 20.4 4.7 0.00059 19.6 3.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ01776.1 - 0.0029 17.2 0.2 0.0071 16.0 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 OAJ01776.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.1 OAJ01776.1 - 0.052 13.0 3.6 0.1 12.0 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Pkinase PF00069.20 OAJ01777.1 - 1.9e-73 246.8 0.0 2.6e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01777.1 - 5.2e-42 143.7 0.0 7.6e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01777.1 - 1.7e-10 40.3 0.0 5.4e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 OAJ01777.1 - 0.066 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aft1_HRA PF11786.3 OAJ01778.1 - 7.2e-11 42.1 22.3 7.2e-11 42.1 15.5 4.0 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_1 PF00170.16 OAJ01778.1 - 1.3e-10 41.0 4.2 2.3e-10 40.2 2.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ01778.1 - 2e-06 27.4 6.6 2e-06 27.4 4.6 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Colipase PF01114.13 OAJ01779.1 - 0.006 16.0 1.0 0.006 16.0 0.7 9.4 8 1 1 9 9 9 3 Colipase, N-terminal domain Ret_tiss PF10044.4 OAJ01779.1 - 0.11 13.0 0.0 0.99 9.9 0.0 2.2 2 0 0 2 2 2 0 Retinal tissue protein AAA_2 PF07724.9 OAJ01780.1 - 2.6e-47 160.9 0.0 1.5e-43 148.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 OAJ01780.1 - 4e-23 81.1 0.2 1.6e-22 79.1 0.2 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 OAJ01780.1 - 5.5e-23 81.6 0.0 1.8e-13 50.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ01780.1 - 9.6e-13 48.0 0.0 7.5e-06 25.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 OAJ01780.1 - 2.2e-12 46.7 2.3 1.3e-05 24.9 0.3 4.0 3 0 0 3 3 3 2 Clp amino terminal domain AAA_16 PF13191.1 OAJ01780.1 - 3.6e-12 46.6 15.3 2.2e-07 31.0 0.0 5.6 5 3 1 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 OAJ01780.1 - 2.3e-11 43.9 0.8 0.00085 19.4 0.0 4.9 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 OAJ01780.1 - 6.2e-08 32.2 0.0 0.016 14.5 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 OAJ01780.1 - 4.3e-07 30.7 3.9 0.01 16.6 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 OAJ01780.1 - 1.5e-06 28.5 0.2 0.15 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 OAJ01780.1 - 2.2e-06 27.2 0.0 0.0022 17.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 OAJ01780.1 - 2e-05 24.5 0.0 0.022 14.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 OAJ01780.1 - 7.4e-05 22.8 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 OAJ01780.1 - 9.4e-05 22.2 7.4 0.037 13.7 0.0 4.2 4 1 1 5 5 4 1 Archaeal ATPase Zeta_toxin PF06414.7 OAJ01780.1 - 0.00011 21.3 0.0 0.02 13.9 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.8 OAJ01780.1 - 0.00018 20.5 0.0 0.58 9.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF258 PF03193.11 OAJ01780.1 - 0.00021 20.5 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 OAJ01780.1 - 0.00025 20.7 2.1 0.087 12.5 0.1 3.4 3 0 0 3 3 3 1 Part of AAA domain MobB PF03205.9 OAJ01780.1 - 0.00034 20.3 0.0 0.34 10.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 OAJ01780.1 - 0.00039 19.5 0.1 0.17 10.8 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 OAJ01780.1 - 0.00039 20.1 0.0 0.085 12.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 OAJ01780.1 - 0.00073 18.7 0.0 0.18 10.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ01780.1 - 0.00081 19.3 0.2 1.6 8.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 OAJ01780.1 - 0.0012 18.5 0.0 0.61 9.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ01780.1 - 0.002 17.6 0.8 2.4 7.4 0.0 3.8 3 1 1 4 4 4 1 AAA-like domain NTPase_1 PF03266.10 OAJ01780.1 - 0.0027 17.4 0.0 2.2 7.9 0.0 3.1 3 0 0 3 3 2 1 NTPase T2SE PF00437.15 OAJ01780.1 - 0.0033 16.3 0.0 0.071 11.9 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 OAJ01780.1 - 0.0036 16.8 0.0 3.3 7.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 OAJ01780.1 - 0.0047 16.3 0.0 0.73 9.2 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC_tran PF00005.22 OAJ01780.1 - 0.0066 16.7 0.1 1.6 9.0 0.0 3.1 3 0 0 3 3 2 1 ABC transporter ATP_bind_1 PF03029.12 OAJ01780.1 - 0.012 15.1 0.0 0.84 9.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 OAJ01780.1 - 0.018 14.4 6.7 2.3 7.5 0.0 4.5 4 1 0 5 5 5 0 AAA domain UPF0079 PF02367.12 OAJ01780.1 - 0.019 14.6 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 OAJ01780.1 - 0.025 14.1 0.0 13 5.3 0.0 3.7 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 OAJ01780.1 - 0.027 14.9 0.0 4.8 7.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 OAJ01780.1 - 0.033 14.4 0.0 0.033 14.4 0.0 3.4 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.1 OAJ01780.1 - 0.095 12.6 0.0 24 4.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain PduV-EutP PF10662.4 OAJ01780.1 - 0.12 11.9 0.0 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Seryl_tRNA_N PF02403.17 OAJ01780.1 - 1.7 8.6 15.3 1.7 8.7 3.3 3.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4337 PF14235.1 OAJ01780.1 - 6.3 6.6 7.6 19 5.0 5.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) SNARE_assoc PF09335.6 OAJ01781.1 - 4.9e-12 46.1 5.3 1.3e-11 44.7 3.7 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein AMPKBI PF04739.10 OAJ01781.1 - 0.036 13.9 0.4 0.078 12.8 0.3 1.5 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Nop14 PF04147.7 OAJ01781.1 - 8.9 4.0 10.3 14 3.4 7.1 1.2 1 0 0 1 1 1 0 Nop14-like family HAD PF12710.2 OAJ01782.1 - 6.2e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Metallophos PF00149.23 OAJ01783.1 - 7.5e-12 45.0 0.1 3.2e-11 42.9 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 OAJ01784.1 - 2.3e-34 117.7 0.0 3.1e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ01784.1 - 4.2e-14 52.3 0.0 5.4e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 OAJ01784.1 - 1.8e-11 43.5 0.2 3.5e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 OAJ01784.1 - 0.071 13.0 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme FKBP_C PF00254.23 OAJ01786.1 - 1e-29 102.3 0.0 1.2e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FAD_binding_2 PF00890.19 OAJ01788.1 - 2.5e-82 276.9 0.5 3.8e-82 276.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 OAJ01788.1 - 3.7e-21 74.7 0.1 1.1e-20 73.2 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 OAJ01788.1 - 1.8e-13 50.1 1.4 2.8e-12 46.2 0.9 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ01788.1 - 1.1e-10 41.3 1.1 1.2e-09 38.0 0.2 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ01788.1 - 1.4e-07 31.5 7.3 3e-06 27.2 3.8 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ01788.1 - 5.7e-07 28.9 0.4 1.2e-06 27.8 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ01788.1 - 1.2e-06 27.6 0.9 0.0027 16.6 0.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ01788.1 - 1.3e-06 27.1 1.6 6.4e-05 21.6 0.0 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 OAJ01788.1 - 8.5e-06 25.0 0.6 1.8e-05 23.9 0.4 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 OAJ01788.1 - 3.8e-05 22.8 0.6 0.00077 18.6 0.2 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 OAJ01788.1 - 4.4e-05 23.6 0.9 0.00014 21.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ01788.1 - 0.0012 19.1 0.3 0.006 16.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAJ01788.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 OAJ01788.1 - 0.0032 17.2 0.1 0.2 11.4 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAJ01788.1 - 0.015 14.8 0.1 0.046 13.2 0.0 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 OAJ01788.1 - 0.018 15.2 0.1 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Chorion_2 PF03964.10 OAJ01788.1 - 0.018 15.5 2.2 0.043 14.3 1.5 1.6 1 0 0 1 1 1 0 Chorion family 2 GDI PF00996.13 OAJ01788.1 - 0.025 12.8 0.1 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 OAJ01788.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF756 PF05506.7 OAJ01788.1 - 0.061 13.8 0.5 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Ded_cyto PF06920.8 OAJ01789.1 - 3.5e-38 130.6 0.7 2.8e-37 127.7 0.0 2.4 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 OAJ01789.1 - 1.4e-30 106.3 0.0 2.8e-29 102.0 0.0 2.4 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Retrotrans_gag PF03732.12 OAJ01790.1 - 0.006 16.6 0.8 0.012 15.6 0.5 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein FUSC_2 PF13515.1 OAJ01791.1 - 1e-15 57.8 21.7 1.9e-15 56.9 11.7 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ01791.1 - 5.1e-10 38.5 5.6 9.1e-10 37.7 2.1 2.3 2 1 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 OAJ01791.1 - 9.9e-09 34.1 17.5 9.9e-09 34.1 12.2 3.7 4 1 0 4 4 4 1 Fusaric acid resistance protein family DUF2422 PF10337.4 OAJ01791.1 - 7.6e-08 31.5 0.2 7.6e-08 31.5 0.1 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF2422) DUF939 PF06081.6 OAJ01791.1 - 2.5e-05 24.1 4.8 6.7e-05 22.7 3.3 1.8 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF939) DUF2421 PF10334.4 OAJ01791.1 - 0.00017 21.2 1.2 0.00043 19.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) PhoU PF01895.14 OAJ01791.1 - 0.18 12.2 1.6 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 PhoU domain BCA_ABC_TP_C PF12399.3 OAJ01792.1 - 0.13 11.9 2.4 0.44 10.2 1.6 1.9 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Ctr PF04145.10 OAJ01792.1 - 1.1 9.2 4.7 24 4.9 0.0 2.9 2 0 0 2 2 2 0 Ctr copper transporter family LIP PF03583.9 OAJ01793.1 - 2e-53 181.5 0.1 2.7e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ01793.1 - 1.2e-07 31.5 0.2 2.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ01793.1 - 4.9e-07 29.8 0.2 1.1e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ01793.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold CK_II_beta PF01214.13 OAJ01795.1 - 3e-73 245.2 0.0 3.8e-73 244.9 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DEC-1_N PF04625.8 OAJ01795.1 - 0.096 11.3 1.1 0.14 10.8 0.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CCDC-167 PF15188.1 OAJ01795.1 - 0.18 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 rve PF00665.21 OAJ01796.1 - 8.2e-13 48.5 0.0 1.9e-11 44.1 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 OAJ01796.1 - 2.3e-05 23.9 0.0 4.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 OAJ01796.1 - 0.033 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_3 PF13456.1 OAJ01796.1 - 0.066 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like RVP_2 PF08284.6 OAJ01796.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease RhoGAP PF00620.22 OAJ01797.1 - 9.7e-07 28.5 0.0 1.1e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 RhoGAP domain FCH PF00611.18 OAJ01797.1 - 3.7e-05 23.8 0.0 0.0032 17.6 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain LIP PF03583.9 OAJ01798.1 - 2.4e-49 168.1 0.0 4.6e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Secretory lipase MFS_1 PF07690.11 OAJ01798.1 - 2.3e-48 164.7 34.5 6.7e-46 156.6 11.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ01798.1 - 4e-09 35.5 3.5 4e-09 35.5 2.4 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter Abhydrolase_5 PF12695.2 OAJ01798.1 - 1.2e-06 28.3 0.1 3.8e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family OATP PF03137.15 OAJ01798.1 - 2.2e-05 22.7 1.7 0.0015 16.6 1.2 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family ESSS PF10183.4 OAJ01798.1 - 0.11 12.9 0.3 0.11 12.9 0.2 2.8 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4231 PF14015.1 OAJ01798.1 - 8.3 6.4 6.4 24 4.9 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) VIT1 PF01988.14 OAJ01799.1 - 2.2 7.7 4.2 5 6.5 2.9 1.6 1 0 0 1 1 1 0 VIT family DUF866 PF05907.8 OAJ01800.1 - 8.1e-37 126.1 0.3 1e-36 125.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.6 OAJ01800.1 - 0.0017 18.2 2.2 0.011 15.5 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) Cytochrome_C7 PF14522.1 OAJ01800.1 - 0.043 13.4 1.0 0.09 12.4 0.7 1.5 1 0 0 1 1 1 0 Cytochrome c7 Lar_restr_allev PF14354.1 OAJ01800.1 - 5.3 7.4 7.0 2.2 8.6 0.5 2.7 1 1 2 3 3 3 0 Restriction alleviation protein Lar TPP_enzyme_N PF02776.13 OAJ01802.1 - 3.4e-56 189.4 0.0 3.4e-56 189.4 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 OAJ01802.1 - 1.9e-48 163.8 0.1 3.3e-47 159.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 OAJ01802.1 - 6.4e-39 132.8 0.3 3.1e-38 130.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 OAJ01802.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit HsbA PF12296.3 OAJ01803.1 - 3.7e-17 62.3 13.3 5.6e-17 61.7 9.2 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A RTC4 PF14474.1 OAJ01809.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain PsaL PF02605.10 OAJ01809.1 - 0.13 11.7 1.2 0.39 10.2 0.1 1.9 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI SCPU PF05229.10 OAJ01810.1 - 0.078 13.0 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Spore Coat Protein U domain NTP_transf_2 PF01909.18 OAJ01814.1 - 6.8e-08 32.7 0.2 1.8e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain HTH_23 PF13384.1 OAJ01815.1 - 0.0063 16.1 0.9 0.18 11.4 0.0 3.6 2 1 0 2 2 2 1 Homeodomain-like domain GCR1_C PF12550.3 OAJ01815.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_28 PF13518.1 OAJ01815.1 - 2.8 8.0 7.3 0.42 10.6 0.1 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain NUC205 PF08168.6 OAJ01823.1 - 0.12 11.7 0.2 0.24 10.8 0.2 1.5 1 0 0 1 1 1 0 NUC205 domain PIF1 PF05970.9 OAJ01824.1 - 1.2e-22 80.3 0.0 2.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01824.1 - 3e-11 43.2 0.0 4.8e-10 39.3 0.0 2.8 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAJ01824.1 - 3.4e-09 36.6 0.0 8.5e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ01824.1 - 6.2e-08 32.2 1.6 3.5e-07 29.8 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 OAJ01824.1 - 0.0049 17.0 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ01824.1 - 0.0099 15.8 1.0 0.033 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Torsin PF06309.6 OAJ01824.1 - 0.028 14.2 0.0 0.095 12.5 0.0 1.9 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 OAJ01824.1 - 0.2 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 OAJ01824.1 - 0.23 11.6 0.0 0.59 10.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 OAJ01824.1 - 0.49 9.3 0.0 0.95 8.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Anoctamin PF04547.7 OAJ01825.1 - 0.025 13.2 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Baculo_PEP_C PF04513.7 OAJ01825.1 - 0.069 12.9 0.8 0.53 10.1 0.4 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.7 OAJ01825.1 - 0.68 9.8 2.8 15 5.5 0.9 2.7 2 1 0 2 2 2 0 MbeD/MobD like Ribosomal_L37ae PF01780.14 OAJ01826.1 - 0.069 13.0 2.3 0.11 12.3 0.4 2.1 1 1 1 2 2 2 0 Ribosomal L37ae protein family Cyclin_N PF00134.18 OAJ01827.1 - 6.1e-20 71.0 0.0 1.3e-19 69.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ01827.1 - 1.4e-09 37.8 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 OAJ01829.1 - 1.2e-17 63.6 0.5 7.1e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ01829.1 - 1.8e-15 56.8 1.0 3.8e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Mpp10 PF04006.7 OAJ01830.1 - 0.22 9.8 15.6 0.32 9.3 10.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.1 OAJ01830.1 - 1.9 7.8 8.9 3.7 6.9 6.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 OAJ01830.1 - 3.3 5.3 4.7 1.2 6.7 1.7 1.3 2 0 0 2 2 2 0 Ycf1 MULE PF10551.4 OAJ01831.1 - 2.9e-19 69.0 0.0 6.5e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ01831.1 - 3.9e-08 32.2 0.0 6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Elongin_A PF06881.6 OAJ01832.1 - 3.1 8.2 7.0 33 4.9 0.0 3.6 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Transposase_21 PF02992.9 OAJ01833.1 - 2.1e-18 66.2 0.1 3.6e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Transposase family tnp2 zf-RING_4 PF14570.1 OAJ01834.1 - 0.0022 17.5 1.6 0.0041 16.6 1.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 OAJ01834.1 - 5 6.9 7.7 1.8 8.3 0.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 zf-C2H2 PF00096.21 OAJ01835.1 - 0.00063 19.9 3.4 0.024 14.9 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ01835.1 - 0.006 16.8 3.0 0.065 13.5 0.4 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ01835.1 - 0.03 14.4 4.5 0.054 13.6 1.7 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 OAJ01835.1 - 0.075 12.7 1.0 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 OAJ01835.1 - 0.24 11.7 2.3 12 6.3 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 OAJ01835.1 - 0.6 10.4 3.1 2.9 8.3 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double domain FHA PF00498.21 OAJ01837.1 - 0.027 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 FHA domain F_actin_bind PF08919.5 OAJ01837.1 - 0.1 12.3 0.2 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 F-actin binding CytochromB561_N PF09786.4 OAJ01837.1 - 0.95 7.8 16.7 1.4 7.2 11.6 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Actin PF00022.14 OAJ01838.1 - 1.2e-158 527.7 0.0 1.3e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 OAJ01838.1 - 0.026 12.8 0.0 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ESSS PF10183.4 OAJ01838.1 - 0.073 13.4 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ubiquitin PF00240.18 OAJ01839.1 - 1.3e-33 114.2 0.7 1.7e-33 113.8 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 OAJ01839.1 - 1.1e-29 101.7 8.3 1.7e-29 101.1 5.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 OAJ01839.1 - 5e-19 67.7 0.5 6.6e-19 67.3 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ01839.1 - 4e-05 23.7 0.1 0.00015 21.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ01839.1 - 0.00085 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ01839.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ01839.1 - 0.037 14.2 0.1 0.041 14.0 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-DHHC PF01529.15 OAJ01839.1 - 0.31 10.4 2.6 0.45 9.8 1.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_L18ae PF01775.12 OAJ01840.1 - 5.7e-58 194.1 0.5 6.9e-58 193.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF2883 PF11097.3 OAJ01840.1 - 0.092 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) PDT PF00800.13 OAJ01841.1 - 1.7e-40 138.5 0.4 4.9e-35 120.7 0.0 3.2 2 1 0 2 2 2 2 Prephenate dehydratase Pkinase PF00069.20 OAJ01842.1 - 1.1e-37 129.5 0.0 4.6e-11 42.3 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01842.1 - 8.8e-16 57.7 0.0 2e-08 33.6 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase F-box PF00646.28 OAJ01842.1 - 0.07 12.8 1.6 0.2 11.3 1.1 1.7 1 0 0 1 1 1 0 F-box domain QueF PF14489.1 OAJ01843.1 - 0.12 12.3 0.1 2.3 8.2 0.0 2.1 2 0 0 2 2 2 0 QueF-like protein FAD_binding_4 PF01565.18 OAJ01851.1 - 1.2e-14 54.0 0.1 7.9e-08 31.8 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain BBE PF08031.7 OAJ01851.1 - 3.3e-05 23.7 0.0 7.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Serglycin PF04360.7 OAJ01851.1 - 0.0011 18.7 2.6 0.0011 18.7 1.8 3.5 4 0 0 4 4 4 1 Serglycin FKBP_C PF00254.23 OAJ01852.1 - 2.4e-34 117.2 0.7 9.8e-34 115.2 0.0 2.1 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.13 OAJ01852.1 - 5.3e-07 29.3 12.2 7.5e-07 28.8 8.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAJ01852.1 - 2.2e-05 24.7 22.7 0.0073 16.6 2.6 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) ApoLp-III PF07464.6 OAJ01852.1 - 0.00013 21.9 24.0 0.00021 21.3 16.6 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Synuclein PF01387.12 OAJ01852.1 - 0.00066 19.5 15.6 0.00066 19.5 10.8 3.1 1 1 1 2 2 1 1 Synuclein YtxH PF12732.2 OAJ01852.1 - 0.0031 17.8 26.1 0.026 14.9 3.3 3.4 1 1 1 2 2 2 1 YtxH-like protein Tropomyosin_1 PF12718.2 OAJ01852.1 - 0.0052 16.6 12.5 0.0052 16.6 8.7 1.4 1 1 0 1 1 1 1 Tropomyosin like Prominin PF05478.6 OAJ01852.1 - 0.0094 13.5 4.7 0.013 13.0 3.3 1.2 1 0 0 1 1 1 1 Prominin Phasin_2 PF09361.5 OAJ01852.1 - 0.017 15.1 20.3 0.42 10.6 8.5 2.5 2 0 0 2 2 2 0 Phasin protein Borrelia_P83 PF05262.6 OAJ01852.1 - 0.032 12.4 24.5 0.044 12.0 17.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein ATG_C PF09333.6 OAJ01852.1 - 0.044 13.9 11.7 0.051 13.7 0.6 3.1 1 1 0 2 2 2 0 ATG C terminal domain HisKA_3 PF07730.8 OAJ01852.1 - 0.075 13.3 8.6 8.8e+02 0.3 6.0 3.7 1 1 0 1 1 1 0 Histidine kinase Mitofilin PF09731.4 OAJ01852.1 - 0.091 11.3 19.6 0.12 11.0 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Tape_meas_lam_C PF09718.5 OAJ01852.1 - 0.094 12.6 12.7 0.6 10.0 0.2 3.0 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Baculo_PEP_C PF04513.7 OAJ01852.1 - 0.095 12.5 0.6 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 OAJ01852.1 - 1 9.3 9.8 11 5.9 0.7 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF812 PF05667.6 OAJ01852.1 - 1.4 7.2 14.0 1.7 7.0 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ZYG-11_interact PF05884.7 OAJ01852.1 - 1.7 7.6 6.9 0.64 9.0 3.1 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 HSP9_HSP12 PF04119.7 OAJ01852.1 - 2.4 8.2 14.1 5.3 7.2 0.8 4.0 1 1 2 3 3 3 0 Heat shock protein 9/12 Activator-TraM PF11657.3 OAJ01852.1 - 3.5 7.1 20.1 0.52 9.7 5.4 2.5 1 1 1 2 2 2 0 Transcriptional activator TraM Perilipin PF03036.11 OAJ01852.1 - 5.3 5.7 16.4 2.6 6.7 6.3 2.5 1 1 1 2 2 2 0 Perilipin family WES_acyltransf PF03007.11 OAJ01853.1 - 1.4e-15 57.5 0.0 3.3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Fungal_trans PF04082.13 OAJ01854.1 - 1.2e-26 93.1 0.0 2.2e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 OAJ01854.1 - 3.8e-09 36.3 11.5 1.2e-05 25.3 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ01854.1 - 4e-07 29.8 10.3 0.00025 21.1 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ01854.1 - 0.099 12.9 0.2 0.099 12.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain MFS_1 PF07690.11 OAJ01855.1 - 5e-16 58.3 53.2 6.2e-12 44.8 20.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DRIM PF07539.7 OAJ01856.1 - 3.5e-41 139.9 0.0 1.2e-40 138.1 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis TFIIA PF03153.8 OAJ01856.1 - 0.0032 17.4 10.5 0.0032 17.4 7.3 3.2 4 0 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit GIT_SHD PF08518.6 OAJ01857.1 - 7.9e-26 89.1 8.3 1.9e-14 52.7 0.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AAA_13 PF13166.1 OAJ01857.1 - 0.28 9.6 15.2 0.64 8.4 10.5 1.6 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 OAJ01857.1 - 0.83 6.8 26.4 2.2 5.5 18.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) F-box-like PF12937.2 OAJ01858.1 - 0.027 14.1 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 OAJ01858.1 - 0.047 13.3 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain AT_hook PF02178.14 OAJ01858.1 - 1.9 8.4 16.4 1.2 9.0 5.5 3.5 2 0 0 2 2 2 0 AT hook motif UvdE PF03851.9 OAJ01859.1 - 3.9e-91 304.8 0.0 5.5e-91 304.4 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DTHCT PF08070.6 OAJ01859.1 - 2.1 9.0 20.2 0.72 10.5 9.1 3.0 2 0 0 2 2 2 0 DTHCT (NUC029) region G-alpha PF00503.15 OAJ01860.1 - 1.4e-126 422.3 0.3 1.6e-126 422.1 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ01860.1 - 3e-15 55.9 0.5 7.3e-10 38.3 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ01860.1 - 0.00013 21.2 0.2 0.15 11.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ01860.1 - 0.00024 21.5 0.1 0.16 12.4 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 OAJ01860.1 - 0.038 13.5 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Calpain_III PF01067.17 OAJ01861.1 - 1.3e-21 76.7 0.0 5.4e-12 45.5 0.0 4.0 4 0 0 4 4 4 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 OAJ01861.1 - 5.7e-18 64.9 0.0 9.7e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DIM1 PF02966.11 OAJ01862.1 - 3.1e-66 220.9 0.1 3.4e-66 220.7 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 OAJ01862.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 OAJ01862.1 - 0.0029 17.5 0.0 0.0064 16.4 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ01862.1 - 0.021 15.0 0.1 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain RVT_2 PF07727.9 OAJ01863.1 - 8.3e-89 296.7 0.0 1.1e-88 296.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ01863.1 - 1.7e-26 92.6 0.1 5.1e-26 91.1 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ01863.1 - 8.5e-06 25.3 0.1 2.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ01863.1 - 0.00087 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Myb_Cef PF11831.3 OAJ01864.1 - 5.2e-54 182.9 0.0 5.2e-54 182.9 0.0 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 OAJ01864.1 - 1.6e-22 79.2 4.7 3.3e-11 43.0 0.4 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ01864.1 - 2.8e-20 72.1 7.6 2.9e-13 49.7 2.7 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain HALZ PF02183.13 OAJ01864.1 - 0.011 15.4 1.8 0.035 13.8 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF217 PF02697.9 OAJ01864.1 - 0.58 10.4 5.1 0.33 11.2 0.5 3.0 2 0 0 2 2 2 0 Uncharacterized ACR, COG1753 FlxA PF14282.1 OAJ01864.1 - 4.7 7.1 9.6 0.072 13.0 0.5 2.7 3 0 0 3 3 3 0 FlxA-like protein zf-CCHC_5 PF14787.1 OAJ01866.1 - 8.7e-05 21.9 2.4 0.00037 19.9 1.6 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 OAJ01866.1 - 0.00094 18.9 1.8 0.0018 18.0 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ01866.1 - 0.0069 16.0 3.0 0.0069 16.0 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle UBN2 PF14223.1 OAJ01866.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MRI PF15325.1 OAJ01866.1 - 0.86 10.6 3.3 1.3 9.9 1.1 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection PBP PF01161.15 OAJ01867.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Acyl-CoA_dh_1 PF00441.19 OAJ01871.1 - 8.5e-32 110.3 0.4 1.4e-31 109.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ01871.1 - 6.9e-16 57.4 0.2 1.5e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 OAJ01871.1 - 7.1e-16 57.7 0.0 1.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 OAJ01871.1 - 1.4e-10 41.7 0.3 9.1e-10 39.1 0.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ01871.1 - 7.6e-05 22.9 0.3 0.00015 22.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ01876.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3653 PF12375.3 OAJ01878.1 - 0.13 12.5 3.7 0.4 10.9 2.5 2.0 1 1 0 1 1 1 0 Phage protein Glyco_hydro_2 PF00703.16 OAJ01879.1 - 0.0085 16.5 1.0 0.02 15.3 0.7 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 TEBP_beta PF07404.6 OAJ01879.1 - 2.9 6.9 10.0 3.9 6.4 6.9 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF3043 PF11241.3 OAJ01879.1 - 6.4 6.3 7.6 11 5.6 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PIF1 PF05970.9 OAJ01881.1 - 1.6e-24 86.5 0.0 3.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01881.1 - 6.9e-12 45.3 0.0 2.7e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ01881.1 - 9e-08 31.7 0.0 3.4e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ01881.1 - 1.4e-07 31.4 0.0 5.5e-07 29.4 0.0 2.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ01881.1 - 0.0042 17.0 0.0 0.02 14.8 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ01881.1 - 0.087 12.9 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAJ01881.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Torsin Bunya_RdRp PF04196.7 OAJ01881.1 - 1.5 6.7 0.0 2.3 6.1 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Pyr_redox_2 PF07992.9 OAJ01882.1 - 1.2e-26 93.8 0.0 5.2e-17 62.4 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ01882.1 - 2.8e-11 43.6 0.1 4e-10 39.9 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ01882.1 - 0.00013 22.0 0.1 0.07 13.1 0.0 3.5 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 OAJ01883.1 - 1.3e-06 28.0 0.5 2.2e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Sigma70_ner PF04546.8 OAJ01883.1 - 0.37 10.3 1.8 0.6 9.6 0.3 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Phosphoesterase PF04185.9 OAJ01885.1 - 8.6e-29 100.8 2.8 1.5e-28 100.0 2.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family Histone PF00125.19 OAJ01886.1 - 1.3e-25 89.2 0.0 1.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ01886.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trehalase PF01204.13 OAJ01887.1 - 2.6e-170 567.4 0.3 3.3e-170 567.1 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 OAJ01887.1 - 1.1e-14 53.4 0.1 1.8e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cpn60_TCP1 PF00118.19 OAJ01888.1 - 7.4e-143 476.6 0.2 8.4e-143 476.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 OAJ01888.1 - 0.043 13.6 0.3 1 9.2 0.1 2.7 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.11 OAJ01888.1 - 0.57 10.1 3.9 32 4.4 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain GSHPx PF00255.14 OAJ01889.1 - 2.7e-31 107.1 0.1 3.4e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 OAJ01889.1 - 2e-05 24.1 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ01889.1 - 0.00033 20.3 0.0 0.00078 19.1 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 OAJ01889.1 - 0.033 14.2 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) ING PF12998.2 OAJ01890.1 - 3.4e-14 53.0 0.1 2.5e-06 27.6 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ01890.1 - 2.3e-09 36.8 6.9 3.8e-09 36.1 4.8 1.4 1 0 0 1 1 1 1 PHD-finger AT_hook PF02178.14 OAJ01890.1 - 0.091 12.4 6.9 0.65 9.8 4.8 2.7 1 0 0 1 1 1 0 AT hook motif RAG2_PHD PF13341.1 OAJ01890.1 - 0.24 11.3 0.6 1.2 9.1 0.2 2.0 2 0 0 2 2 2 0 RAG2 PHD domain Sigma70_ner PF04546.8 OAJ01890.1 - 3.2 7.3 16.0 0.38 10.3 5.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Histone PF00125.19 OAJ01891.1 - 1.4e-22 79.5 0.4 1.9e-22 79.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ01891.1 - 4.4e-07 29.8 0.1 8.5e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 OAJ01891.1 - 0.00037 20.7 0.0 0.00058 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 OAJ01891.1 - 0.034 14.6 0.3 0.045 14.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 OAJ01891.1 - 0.036 13.5 0.1 0.059 12.8 0.1 1.4 1 1 0 1 1 1 0 Replication protein C N-terminal domain F-box PF00646.28 OAJ01892.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain RA PF00788.18 OAJ01893.1 - 1.3e-19 70.5 0.0 1.2e-09 38.5 0.0 3.9 3 0 0 3 3 3 3 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 OAJ01893.1 - 9.7e-07 28.0 0.0 1.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ01893.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PAP2 PF01569.16 OAJ01897.1 - 2.3e-16 59.6 5.3 2.3e-16 59.6 3.7 1.9 2 0 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.13 OAJ01898.1 - 2.3e-22 79.1 0.1 8.2e-22 77.3 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ01898.1 - 2.1e-09 37.1 6.8 3.3e-09 36.4 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sulfate_transp PF00916.15 OAJ01899.1 - 3e-79 265.9 7.3 5.5e-79 265.0 5.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 OAJ01899.1 - 3.1e-31 106.8 3.9 3.1e-31 106.8 2.7 3.6 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 OAJ01899.1 - 1.9e-10 40.1 0.0 3.7e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Abhydrolase_4 PF08386.5 OAJ01900.1 - 2e-14 53.3 0.0 7.9e-14 51.4 0.0 1.9 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ01900.1 - 8.6e-12 45.0 0.0 7.5e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ01900.1 - 1.6e-07 31.4 0.0 1.4e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ01900.1 - 0.00031 20.5 0.0 0.0026 17.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dec-1 PF04624.9 OAJ01900.1 - 0.7 9.5 1.7 1.1 8.9 0.3 1.9 2 0 0 2 2 2 0 Dec-1 repeat Fibrillarin PF01269.12 OAJ01901.1 - 4.7e-107 356.1 0.0 5.9e-107 355.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 OAJ01901.1 - 5.2e-05 22.8 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 OAJ01901.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ01901.1 - 0.0087 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pex14_N PF04695.8 OAJ01902.1 - 0.0081 16.2 0.8 0.0081 16.2 0.5 2.3 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 OAJ01902.1 - 0.35 9.0 4.5 0.43 8.7 3.1 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 OAJ01902.1 - 9.8 5.5 16.9 22 4.4 11.7 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fungal_trans PF04082.13 OAJ01903.1 - 4.5e-30 104.3 0.1 7.3e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ01903.1 - 3.3e-09 36.4 6.3 6e-09 35.6 4.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain H_lectin PF09458.5 OAJ01904.1 - 1.7e-19 69.2 0.0 4.6e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 H-type lectin domain CorA PF01544.13 OAJ01904.1 - 7.6 5.4 7.2 1.3 8.0 0.9 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein H_lectin PF09458.5 OAJ01905.1 - 3.9e-20 71.2 0.5 4.2e-09 35.9 0.0 3.7 4 0 0 4 4 4 2 H-type lectin domain dsrm PF00035.20 OAJ01906.1 - 1.2e-07 32.2 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 OAJ01906.1 - 6.2e-07 29.4 0.0 0.031 14.2 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 OAJ01906.1 - 0.00027 21.3 0.0 0.00065 20.1 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain WD40 PF00400.27 OAJ01907.1 - 1.3e-46 154.8 9.7 7.5e-11 41.4 0.3 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 OAJ01907.1 - 0.022 12.9 4.0 0.45 8.5 0.0 3.7 3 2 1 4 4 4 0 Nucleoporin Nup120/160 SNF2_N PF00176.18 OAJ01908.1 - 6.7e-71 238.5 0.4 1.1e-70 237.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ01908.1 - 2.1e-14 53.1 0.0 8e-14 51.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01908.1 - 1.1e-07 31.8 0.0 3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.8 OAJ01908.1 - 5.2e-05 22.9 8.2 5.2e-05 22.9 5.7 2.2 2 0 0 2 2 2 1 HSA DEAD PF00270.24 OAJ01908.1 - 6.5e-05 22.4 0.0 0.00021 20.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 OAJ01908.1 - 0.012 14.4 0.4 3.1 6.5 0.1 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DIOX_N PF14226.1 OAJ01909.1 - 1.5e-15 57.7 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 OAJ01909.1 - 4.5e-12 46.1 0.0 8.1e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aminotran_5 PF00266.14 OAJ01910.1 - 8.6e-32 110.2 0.0 3.8e-31 108.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V hDGE_amylase PF14701.1 OAJ01911.1 - 1.1e-157 525.2 0.0 1.6e-157 524.7 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 OAJ01911.1 - 2e-106 355.8 0.0 2.9e-106 355.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 OAJ01911.1 - 2.8e-78 262.6 0.0 4.3e-78 262.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 OAJ01911.1 - 2e-17 62.8 0.0 3.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 OAJ01911.1 - 0.0056 16.1 0.0 0.3 10.4 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Ribosomal_L35Ae PF01247.13 OAJ01912.1 - 6.4e-39 131.6 0.6 7.2e-39 131.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 OAJ01912.1 - 0.026 14.4 0.1 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain IPPT PF01715.12 OAJ01913.1 - 9.3e-47 159.1 1.4 2.4e-26 92.2 0.2 3.4 2 1 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 OAJ01913.1 - 8.6e-05 23.3 0.3 0.00039 21.2 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 OAJ01913.1 - 0.0054 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ01913.1 - 0.0091 16.3 4.1 0.072 13.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 OAJ01913.1 - 0.021 13.7 0.4 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 OAJ01913.1 - 0.024 14.6 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 OAJ01913.1 - 0.054 12.7 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 OAJ01913.1 - 0.056 13.4 0.4 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RepA_C PF04796.7 OAJ01913.1 - 0.067 12.8 0.2 0.44 10.1 0.1 2.3 2 0 0 2 2 2 0 Plasmid encoded RepA protein IPT PF01745.11 OAJ01913.1 - 0.068 12.3 0.4 0.23 10.6 0.3 1.8 1 1 0 1 1 1 0 Isopentenyl transferase AAA_33 PF13671.1 OAJ01913.1 - 0.92 9.3 4.6 0.97 9.2 0.0 3.2 4 1 0 4 4 4 0 AAA domain DUF423 PF04241.10 OAJ01914.1 - 1.5e-25 88.8 1.9 1.5e-25 88.8 1.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Glyco_transf_28 PF03033.15 OAJ01915.1 - 1.3e-27 96.2 0.1 4.6e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ01915.1 - 8.2e-08 31.6 0.5 0.0012 18.3 0.0 3.1 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ01915.1 - 0.00076 18.1 0.0 0.0028 16.3 0.0 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ01915.1 - 0.12 12.5 0.0 0.45 10.7 0.0 1.9 1 1 0 1 1 1 0 PH domain Interfer-bind PF09294.5 OAJ01915.1 - 0.32 11.0 0.0 0.71 9.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III Mus7 PF09462.5 OAJ01921.1 - 2.2e-107 360.4 0.0 3.1e-107 359.9 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family MMS22L_N PF14910.1 OAJ01921.1 - 0.0012 17.1 0.0 0.0024 16.2 0.0 1.3 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal UQ_con PF00179.21 OAJ01922.1 - 1.2e-45 154.3 0.0 1.4e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ01922.1 - 0.014 15.1 0.0 0.062 13.0 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B HMG_box PF00505.14 OAJ01923.1 - 5.3e-21 74.6 1.0 5.3e-21 74.6 0.7 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ01923.1 - 6.5e-14 52.0 0.8 6.5e-14 52.0 0.6 1.8 1 1 1 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 OAJ01923.1 - 0.017 14.9 1.6 0.017 14.9 1.1 2.0 2 1 0 2 2 2 0 HMG (high mobility group) box 5 CHDNT PF08073.7 OAJ01923.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF1014 PF06244.7 OAJ01923.1 - 0.1 12.8 0.2 0.1 12.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) SR-25 PF10500.4 OAJ01923.1 - 2 7.8 11.1 2.6 7.4 7.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TSGP1 PF07771.6 OAJ01924.1 - 1.4 8.8 7.2 0.14 12.0 0.6 2.1 2 0 0 2 2 2 0 Tick salivary peptide group 1 Pkinase PF00069.20 OAJ01925.1 - 5.9e-67 225.5 0.2 1.4e-66 224.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01925.1 - 9.6e-35 119.8 0.0 3.2e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ01925.1 - 5.2e-06 25.6 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.14 OAJ01925.1 - 0.00021 20.6 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.17 OAJ01925.1 - 0.03 13.6 0.1 0.03 13.6 0.1 1.9 2 0 0 2 2 2 0 RIO1 family Mg_trans_NIPA PF05653.9 OAJ01926.1 - 1e-63 215.1 0.0 6.3e-59 199.3 0.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 OAJ01926.1 - 8.7e-07 29.1 11.9 7.6e-05 22.8 0.4 2.9 2 1 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 OAJ01926.1 - 0.00027 20.9 1.9 0.00027 20.9 1.3 2.9 2 1 0 2 2 2 1 EamA-like transporter family FAM176 PF14851.1 OAJ01926.1 - 1.3 8.6 6.2 0.27 10.9 0.2 2.7 2 0 0 2 2 2 0 FAM176 family 60KD_IMP PF02096.15 OAJ01927.1 - 2.7e-44 151.2 0.8 4.5e-44 150.4 0.6 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Cob_adeno_trans PF01923.13 OAJ01927.1 - 0.0049 16.6 0.4 0.67 9.7 0.0 2.3 2 0 0 2 2 2 2 Cobalamin adenosyltransferase Synuclein PF01387.12 OAJ01927.1 - 0.011 15.5 5.4 0.024 14.5 3.8 1.4 1 0 0 1 1 1 0 Synuclein Apolipoprotein PF01442.13 OAJ01927.1 - 0.04 13.4 2.2 0.08 12.4 1.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAJ01927.1 - 1.4 9.3 7.7 0.47 10.8 2.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Peptidase_S64 PF08192.6 OAJ01927.1 - 2.4 6.3 5.7 4.1 5.6 3.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 RRM_1 PF00076.17 OAJ01928.1 - 1.8e-19 69.1 0.0 6e-11 41.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ01928.1 - 2e-14 53.1 0.0 1.1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ01928.1 - 4.3e-10 39.4 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 OAJ01929.1 - 3.1e-58 195.7 0.0 3.6e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ01929.1 - 1.6e-19 70.5 0.0 2.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ01929.1 - 2.3e-12 46.5 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ01929.1 - 2.7e-05 23.6 0.0 5.1e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ01929.1 - 3.3e-05 23.1 0.0 4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ01929.1 - 5.8e-05 23.0 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ01929.1 - 0.026 13.7 0.1 0.15 11.2 0.0 2.1 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ01929.1 - 0.04 14.0 0.0 0.24 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ01929.1 - 0.08 12.9 0.2 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 OAJ01930.1 - 1.1e-49 168.9 0.0 1.9e-48 164.8 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ01930.1 - 4.4e-27 94.7 0.0 1.5e-26 93.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ01930.1 - 3.7e-05 23.5 1.3 0.0006 19.6 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ01930.1 - 0.042 13.4 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 OAJ01930.1 - 0.079 12.2 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CUE PF02845.11 OAJ01932.1 - 0.031 13.7 0.2 12 5.4 0.0 3.8 4 0 0 4 4 4 0 CUE domain DUF1687 PF07955.6 OAJ01933.1 - 1.7e-09 37.7 0.2 0.0058 16.6 0.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1687) adh_short_C2 PF13561.1 OAJ01934.1 - 4.3e-28 98.7 0.1 7.2e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ01934.1 - 1.1e-25 90.4 0.1 1.1e-25 90.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ01934.1 - 1.1e-11 44.7 0.1 1.1e-11 44.7 0.1 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ01934.1 - 0.00023 20.6 0.1 0.00049 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAJ01934.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.22 OAJ01935.1 - 1.7e-13 50.7 0.0 3.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF3184 PF11380.3 OAJ01936.1 - 0.32 8.8 0.0 6.5 4.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3184) OmpH PF03938.9 OAJ01938.1 - 9.1 6.1 23.0 26 4.7 16.0 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NIF3 PF01784.13 OAJ01939.1 - 2.6e-53 181.0 0.0 3.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Cyclin_N PF00134.18 OAJ01946.1 - 9.7e-19 67.1 0.0 4e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ01946.1 - 4.6e-08 32.9 0.0 7.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain rve PF00665.21 OAJ01949.1 - 3.1e-15 56.3 0.0 1.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ01949.1 - 4.8e-12 45.7 0.1 1.1e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ01949.1 - 5.9e-06 26.7 0.0 1.3e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 OAJ01949.1 - 2.6e-05 23.8 0.4 8.5e-05 22.1 0.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 OAJ01949.1 - 3.5e-05 23.7 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ01949.1 - 5.7e-05 22.8 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PIF1 PF05970.9 OAJ01950.1 - 4.7e-23 81.7 0.0 1.4e-21 76.9 0.0 2.6 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ01950.1 - 4.3e-14 52.5 2.8 1.4e-11 44.3 0.0 3.4 2 1 1 3 3 3 2 AAA domain Helitron_like_N PF14214.1 OAJ01950.1 - 8.3e-11 41.9 0.4 3.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ01950.1 - 6.1e-06 25.8 3.3 2e-05 24.2 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ01950.1 - 0.0095 15.9 3.2 0.022 14.7 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 OAJ01950.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAJ01950.1 - 0.046 13.7 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ01950.1 - 0.13 11.9 0.1 0.79 9.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Tht1 PF04163.7 OAJ01951.1 - 0.0084 14.5 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein DUF842 PF05811.8 OAJ01951.1 - 0.018 14.5 0.7 0.031 13.7 0.5 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.13 OAJ01951.1 - 0.038 13.5 2.0 0.11 11.9 1.4 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 OAJ01951.1 - 0.12 12.1 0.8 2.3 8.0 0.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2580 PF10824.3 OAJ01951.1 - 0.14 12.4 6.7 2.8 8.3 2.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2580) Utp12 PF04003.7 OAJ01951.1 - 0.15 12.0 0.5 3.5 7.5 0.3 2.6 1 1 0 1 1 1 0 Dip2/Utp12 Family ACOX PF01756.14 OAJ01952.1 - 3.5e-44 150.4 0.0 6.3e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 OAJ01952.1 - 3.9e-15 55.0 0.4 1.3e-14 53.4 0.3 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 OAJ01952.1 - 2e-11 44.2 0.0 6.1e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 OAJ01952.1 - 7.5e-10 39.1 0.8 3.3e-09 37.0 0.6 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Endonuclease_5 PF04493.9 OAJ01953.1 - 1.8e-40 138.5 0.0 4.8e-39 133.8 0.0 2.2 2 0 0 2 2 2 2 Endonuclease V ECH_C PF13766.1 OAJ01954.1 - 0.004 17.2 0.5 0.0073 16.4 0.1 1.6 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Hex_IIIa PF02455.11 OAJ01955.1 - 0.24 10.0 2.9 0.35 9.5 2.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) BNIP2 PF12496.3 OAJ01955.1 - 1.2 9.3 9.7 3.8 7.6 6.8 1.9 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 RXT2_N PF08595.6 OAJ01955.1 - 4.2 7.1 5.5 0.58 9.9 0.4 1.8 1 1 1 2 2 2 0 RXT2-like, N-terminal DUF2457 PF10446.4 OAJ01955.1 - 7.8 5.1 15.9 11 4.5 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AT_hook PF02178.14 OAJ01958.1 - 0.52 10.1 7.5 1.1 9.1 5.2 1.6 1 0 0 1 1 1 0 AT hook motif E1-E2_ATPase PF00122.15 OAJ01960.1 - 7.6e-57 191.9 8.0 1.4e-56 191.1 5.5 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ01960.1 - 1.9e-34 118.7 1.3 1.9e-34 118.7 0.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ01960.1 - 3.6e-27 96.2 0.1 1.2e-21 78.1 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ01960.1 - 1.2e-15 56.7 0.1 5e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ01960.1 - 6.4e-13 48.4 0.0 2e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ01960.1 - 2.4e-11 44.1 0.0 7.1e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ01960.1 - 0.052 13.1 0.1 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_2 PF07719.12 OAJ01961.1 - 1.9e-06 27.3 6.7 2.4 8.2 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ01961.1 - 2.9e-05 23.4 1.8 26 4.6 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ01961.1 - 3.2e-05 23.7 25.0 0.78 9.7 0.1 9.1 7 3 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ01961.1 - 0.00017 21.1 9.3 4 7.1 0.0 6.0 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.1 OAJ01961.1 - 0.00052 20.4 15.1 0.84 10.4 0.0 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ01961.1 - 0.0064 16.3 1.3 0.013 15.3 0.2 2.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 OAJ01961.1 - 3 8.5 0.0 1.7 9.3 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat DEAD PF00270.24 OAJ01962.1 - 7.4e-13 48.3 0.0 1.6e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ01962.1 - 1e-09 38.0 0.0 2.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ01962.1 - 0.005 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CybS PF05328.7 OAJ01964.1 - 5.4e-42 142.5 0.0 8.9e-42 141.8 0.0 1.3 1 0 0 1 1 1 1 CybS Ion_trans PF00520.26 OAJ01965.1 - 7.7e-06 25.2 0.1 1.5e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Ion transport protein PhoD PF09423.5 OAJ01966.1 - 2.1e-138 461.7 8.0 2.4e-138 461.4 5.6 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase START PF01852.14 OAJ01968.1 - 0.00068 19.0 0.0 0.0017 17.6 0.0 1.7 1 0 0 1 1 1 1 START domain Aldo_ket_red PF00248.16 OAJ01972.1 - 2.9e-48 164.1 0.0 3.5e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PNK3P PF08645.6 OAJ01973.1 - 1.8e-38 131.5 1.0 3.4e-22 78.5 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 OAJ01973.1 - 1e-24 87.0 0.1 1.9e-22 79.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ01973.1 - 9.2e-05 21.6 0.0 0.33 9.9 0.0 2.6 1 1 1 2 2 2 2 Zeta toxin MUG113 PF13455.1 OAJ01974.1 - 1.1e-16 61.0 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 OAJ01974.1 - 2.4e-08 34.3 0.0 1e-07 32.2 0.0 2.1 1 1 0 1 1 1 1 T5orf172 domain Kelch_3 PF13415.1 OAJ01975.1 - 9.1e-32 108.5 20.9 1.2e-09 38.0 0.1 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 OAJ01975.1 - 1.5e-28 98.2 16.2 7.4e-08 32.0 0.1 7.2 6 2 0 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.1 OAJ01975.1 - 3e-24 84.6 0.5 3e-24 84.6 0.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 OAJ01975.1 - 8.7e-24 83.0 7.3 1.1e-05 25.1 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 OAJ01975.1 - 7.9e-20 70.1 12.3 4.7e-06 26.5 0.1 6.0 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 OAJ01975.1 - 1.9e-14 52.8 9.9 3.5e-07 29.6 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 OAJ01975.1 - 8.2e-10 38.0 3.7 0.0032 17.1 0.1 5.5 5 1 0 5 5 5 2 Kelch motif Nucleo_P87 PF07267.6 OAJ01975.1 - 1.1 7.8 4.8 2.1 6.9 3.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MSP1_C PF07462.6 OAJ01976.1 - 0.23 9.7 12.3 0.25 9.7 8.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Retinal PF15449.1 OAJ01976.1 - 0.98 6.9 6.4 1.1 6.7 4.4 1.1 1 0 0 1 1 1 0 Retinal protein BSP_II PF05432.6 OAJ01976.1 - 4.3 6.5 20.4 0.23 10.6 9.0 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC27 PF09507.5 OAJ01976.1 - 5 6.2 16.2 5.8 6.0 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2722 PF10846.3 OAJ01976.1 - 5.7 5.8 7.6 6.1 5.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pox_Ag35 PF03286.9 OAJ01976.1 - 7.9 5.9 15.1 2.5 7.5 6.4 2.0 1 1 0 2 2 2 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 OAJ01976.1 - 8.4 5.1 6.5 1.5 7.6 2.3 1.4 2 0 0 2 2 2 0 Floricaula / Leafy protein DNA_pol_phi PF04931.8 OAJ01976.1 - 8.5 4.0 23.0 11 3.6 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_2 PF00891.13 OAJ01977.1 - 1.8e-29 102.6 0.0 3.3e-29 101.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 OAJ01977.1 - 6.1e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Asp PF00026.18 OAJ01978.1 - 7.1e-18 64.9 0.6 1.1e-17 64.3 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Thioesterase PF00975.15 OAJ01979.1 - 3.9e-20 73.0 0.0 5.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 OAJ01979.1 - 3.3e-08 33.6 0.0 4.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ01979.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ01979.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ01979.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 OAJ01979.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 OAJ01980.1 - 7.1e-44 149.9 54.8 3.1e-42 144.5 38.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ01980.1 - 1.5e-18 66.3 24.3 2.7e-18 65.5 16.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ01980.1 - 6.5e-18 64.5 7.4 6.5e-18 64.5 5.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter F-protein PF00469.15 OAJ01981.1 - 1.6 8.0 8.1 8.2 5.7 3.0 2.6 2 1 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF4407 PF14362.1 OAJ01981.1 - 8 5.3 12.4 13 4.5 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CBFD_NFYB_HMF PF00808.18 OAJ01982.1 - 8.4e-16 57.7 0.4 1.6e-15 56.9 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ01982.1 - 2.9e-10 40.1 0.2 4.8e-10 39.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 OAJ01982.1 - 0.048 12.9 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Grp1_Fun34_YaaH PF01184.14 OAJ01983.1 - 8.9e-22 77.4 14.5 1.2e-21 76.9 10.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ketoacyl-synt PF00109.21 OAJ01984.1 - 1.9e-72 243.8 0.2 6.8e-72 241.9 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 OAJ01984.1 - 2.6e-72 243.5 0.0 4.1e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 OAJ01984.1 - 4.2e-57 193.8 0.0 9.6e-57 192.7 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 OAJ01984.1 - 1.5e-53 181.1 3.2 6.9e-53 179.0 0.4 3.0 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 OAJ01984.1 - 1.1e-51 175.8 0.0 1.7e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 OAJ01984.1 - 1.9e-46 158.2 0.0 2.9e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 OAJ01984.1 - 1.9e-44 151.5 0.7 1.9e-44 151.5 0.5 2.8 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 OAJ01984.1 - 2.9e-40 136.8 0.8 5.3e-39 132.7 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 OAJ01984.1 - 5.7e-36 123.7 0.0 2.7e-35 121.5 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein ADH_zinc_N PF00107.21 OAJ01984.1 - 1.4e-14 53.7 0.4 4.6e-14 52.0 0.3 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 OAJ01984.1 - 1.9e-12 47.3 0.1 7.8e-12 45.3 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain PP-binding PF00550.20 OAJ01984.1 - 5.3e-10 39.4 0.0 0.00022 21.4 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 OAJ01984.1 - 5.6e-06 27.2 0.2 0.00011 23.1 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ01984.1 - 6.3e-06 25.9 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DMA PF03474.9 OAJ01984.1 - 0.0027 17.5 0.2 0.018 14.8 0.0 2.4 2 0 0 2 2 2 1 DMRTA motif AMP-binding_C PF13193.1 OAJ01984.1 - 0.0045 17.9 0.2 0.021 15.7 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain PC4 PF02229.11 OAJ01984.1 - 0.67 9.2 1.0 43 3.4 0.0 3.4 4 0 0 4 4 3 0 Transcriptional Coactivator p15 (PC4) p450 PF00067.17 OAJ01985.1 - 9.9e-39 133.1 0.0 1.2e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Homez PF11569.3 OAJ01985.1 - 0.093 11.8 0.0 0.25 10.4 0.0 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez FAD_binding_4 PF01565.18 OAJ01986.1 - 2.4e-27 95.0 0.2 5.4e-27 93.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ01986.1 - 2.4e-08 33.7 0.1 7.7e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_3 PF01494.14 OAJ01987.1 - 1.9e-26 92.9 0.0 3.4e-26 92.1 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ01987.1 - 4.9e-06 25.7 0.1 2.8e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 OAJ01987.1 - 5.4e-05 21.9 0.2 0.048 12.2 0.1 2.2 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 OAJ01987.1 - 0.00021 21.2 0.3 0.0005 20.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ01987.1 - 0.003 17.9 0.4 0.0063 16.9 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ01987.1 - 0.0035 16.3 1.9 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ01987.1 - 0.037 12.8 1.0 0.063 12.1 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 OAJ01987.1 - 0.064 13.3 0.0 0.13 12.2 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ01987.1 - 0.11 12.4 0.2 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 OAJ01988.1 - 3.8e-08 33.5 0.0 6.1e-06 26.3 0.0 2.9 1 1 0 1 1 1 1 NADH(P)-binding DUF249 PF03158.8 OAJ01988.1 - 0.0055 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Multigene family 530 protein Lipoprotein_3 PF00938.12 OAJ01988.1 - 0.057 13.1 0.0 0.092 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipoprotein adh_short PF00106.20 OAJ01988.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase p450 PF00067.17 OAJ01990.1 - 8.5e-59 199.2 0.0 1.5e-58 198.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 FTO_CTD PF12934.2 OAJ01990.1 - 0.049 13.2 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain zf-CCHC_4 PF14392.1 OAJ01991.1 - 0.45 10.2 9.8 0.7 9.6 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle DUF4501 PF14946.1 OAJ01991.1 - 9.8 5.6 10.6 18 4.7 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) DUF966 PF06136.8 OAJ01992.1 - 0.36 10.2 2.3 0.46 9.8 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RVT_1 PF00078.22 OAJ01993.1 - 3.7e-33 114.7 0.0 5.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ01993.1 - 3.7e-11 42.6 0.0 7.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ01993.1 - 1.2e-07 31.9 0.3 3.4e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exonuc_VII_L PF02601.10 OAJ01993.1 - 0.14 11.3 0.2 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit She9_MDM33 PF05546.6 OAJ01998.1 - 2.5e-61 206.8 8.8 3.5e-61 206.3 6.1 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family Na_H_antiport_1 PF06965.7 OAJ01998.1 - 0.062 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Pox_A14 PF05767.7 OAJ01998.1 - 0.26 11.2 1.0 2 8.4 0.0 2.5 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 GDC-P PF02347.11 OAJ01999.1 - 2.7e-185 616.1 0.0 6.3e-173 575.3 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 OAJ01999.1 - 0.00097 18.3 0.0 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Ribosomal_L44 PF00935.14 OAJ02000.1 - 4e-34 116.4 12.2 4e-34 116.4 8.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L44 Peptidase_C48 PF02902.14 OAJ02002.1 - 0.16 11.5 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Ulp1 protease family, C-terminal catalytic domain ADH_zinc_N_2 PF13602.1 OAJ02003.1 - 3.5e-17 63.5 0.4 1.3e-16 61.5 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ02003.1 - 1.8e-13 50.1 0.5 3.3e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ02003.1 - 1.5e-11 44.0 3.5 7.9e-09 35.2 0.1 3.6 3 1 1 4 4 4 2 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 OAJ02003.1 - 0.63 9.9 4.2 0.16 11.8 0.6 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Cauli_VI PF01693.11 OAJ02006.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin GTP_EFTU PF00009.22 OAJ02007.1 - 8.8e-41 139.4 0.0 1.5e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ02007.1 - 9.5e-28 96.1 0.0 2.1e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 OAJ02007.1 - 2.2e-18 65.9 0.0 6.6e-18 64.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 OAJ02007.1 - 6.5e-08 33.0 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ02007.1 - 4.9e-07 29.6 0.0 9.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAJ02007.1 - 9.5e-07 28.8 0.1 3.2e-06 27.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 OAJ02007.1 - 5.9e-05 22.8 0.1 0.00014 21.6 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 OAJ02007.1 - 0.0043 16.4 0.0 0.015 14.6 0.0 1.8 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 OAJ02007.1 - 0.014 15.1 0.1 6.4 6.5 0.0 2.4 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.5 OAJ02007.1 - 0.039 13.1 0.1 0.14 11.3 0.0 2.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 OAJ02007.1 - 0.15 11.3 0.4 1.8 7.8 0.3 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Herpes_LMP2 PF07415.6 OAJ02007.1 - 0.77 8.2 4.2 1.1 7.7 2.9 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Spo7 PF03907.8 OAJ02008.1 - 2.3e-12 46.9 1.2 0.0011 18.5 0.0 3.1 3 0 0 3 3 3 3 Spo7-like protein DUF3989 PF13150.1 OAJ02008.1 - 5.2 6.5 5.5 28 4.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) TFIIA PF03153.8 OAJ02009.1 - 5.8 6.7 20.7 1.7 8.4 6.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CFEM PF05730.6 OAJ02010.1 - 0.028 14.2 4.1 0.043 13.6 2.6 1.6 1 1 0 1 1 1 0 CFEM domain NST1 PF13945.1 OAJ02010.1 - 0.079 13.0 3.3 0.14 12.1 2.3 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator FAM176 PF14851.1 OAJ02010.1 - 0.17 11.5 1.3 0.48 10.1 0.7 1.8 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.3 OAJ02010.1 - 0.27 9.8 2.9 0.36 9.3 2.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BLVR PF06375.6 OAJ02010.1 - 1.4 8.7 10.9 0.56 10.0 5.7 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) FAD_binding_4 PF01565.18 OAJ02011.1 - 5.1e-26 90.7 2.1 9.9e-26 89.8 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ02011.1 - 1.2e-07 31.4 0.1 2.4e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1815 PF08844.5 OAJ02011.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) NLBH PF05211.7 OAJ02011.1 - 0.34 10.1 0.0 0.53 9.4 0.0 1.2 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) RNase_H PF00075.19 OAJ02012.1 - 9.1e-09 35.7 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 RNase H Choline_transpo PF04515.7 OAJ02013.1 - 2.1e-23 82.5 12.6 1.8e-11 43.3 0.0 3.3 3 0 0 3 3 3 3 Plasma-membrane choline transporter Ycf1 PF05758.7 OAJ02013.1 - 4.3 4.9 2.7 7.9 4.0 1.9 1.3 1 0 0 1 1 1 0 Ycf1 TPR_12 PF13424.1 OAJ02014.1 - 5.6e-45 151.1 62.5 1.3e-11 44.3 3.2 5.5 2 1 5 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ02014.1 - 2.1e-22 78.2 36.3 0.00035 20.3 0.7 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02014.1 - 3.6e-12 45.1 18.8 0.2 11.6 0.1 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ02014.1 - 5.2e-08 32.1 8.7 5.9 6.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ02014.1 - 1.3e-07 31.1 24.2 0.0017 17.9 1.5 4.7 2 1 3 5 5 5 4 TPR repeat TPR_7 PF13176.1 OAJ02014.1 - 1.5e-06 27.5 16.5 1.8 8.5 0.1 6.9 7 0 0 7 7 5 3 Tetratricopeptide repeat DUF3366 PF11846.3 OAJ02014.1 - 3.9e-06 26.8 0.3 0.27 11.0 0.0 3.7 1 1 2 3 3 3 2 Domain of unknown function (DUF3366) TPR_14 PF13428.1 OAJ02014.1 - 4.4e-06 26.8 22.3 3.4 8.5 0.1 8.3 5 1 3 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ02014.1 - 3e-05 23.4 15.0 6 6.8 0.1 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ02014.1 - 3.5e-05 23.8 9.2 12 6.7 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc5 PF12862.2 OAJ02014.1 - 0.0004 20.1 8.5 34 4.3 1.6 6.5 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 5 Desmo_N PF06771.6 OAJ02014.1 - 0.0011 18.8 0.0 7.1 6.6 0.0 4.4 1 1 3 4 4 4 1 Viral Desmoplakin N-terminus DUF3856 PF12968.2 OAJ02014.1 - 0.0014 18.4 16.1 0.39 10.5 1.2 4.2 1 1 5 6 6 6 5 Domain of Unknown Function (DUF3856) PPR_3 PF13812.1 OAJ02014.1 - 0.0021 18.1 0.2 24 5.5 0.0 5.4 5 0 0 5 5 4 0 Pentatricopeptide repeat domain Bromodomain PF00439.20 OAJ02014.1 - 0.003 17.4 0.8 38 4.3 0.0 4.9 3 2 1 4 4 4 0 Bromodomain Ssu72 PF04722.8 OAJ02014.1 - 0.0066 15.7 1.1 14 4.9 0.0 4.7 2 1 3 5 5 5 0 Ssu72-like protein TPR_16 PF13432.1 OAJ02014.1 - 0.11 13.1 29.8 1 10.1 0.6 6.1 1 1 6 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_II PF08171.6 OAJ02014.1 - 0.19 11.6 7.2 24 4.9 0.0 5.6 6 0 0 6 6 6 0 Mad3/BUB1 homology region 2 PPR PF01535.15 OAJ02014.1 - 0.45 10.6 9.2 73 3.6 0.0 6.0 6 0 0 6 6 6 0 PPR repeat AP2 PF00847.15 OAJ02014.1 - 1.4 9.1 3.3 55 4.0 0.0 4.1 5 0 0 5 5 4 0 AP2 domain GPI-anchored PF10342.4 OAJ02015.1 - 1.2e-10 41.6 2.7 1.2e-10 41.6 1.9 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family LIP PF03583.9 OAJ02016.1 - 4.3e-54 183.6 0.2 5.8e-54 183.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ02016.1 - 3e-07 30.2 0.1 6.9e-07 29.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ02016.1 - 3.3e-07 30.4 0.0 5.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ02016.1 - 4.4e-05 22.8 0.2 0.047 12.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ02016.1 - 0.062 13.0 0.2 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Cutinase Ribosomal_L14e PF01929.12 OAJ02017.1 - 1.2e-24 86.4 0.6 1.6e-24 86.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 OAJ02017.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 KOW motif Laminin_I PF06008.9 OAJ02019.1 - 2.5 7.3 9.3 0.028 13.7 0.8 1.8 3 0 0 3 3 3 0 Laminin Domain I BSD PF03909.12 OAJ02020.1 - 3.7e-17 61.7 0.0 5e-12 45.3 0.0 2.7 2 0 0 2 2 2 2 BSD domain DUF4632 PF15451.1 OAJ02020.1 - 0.25 11.3 7.0 0.11 12.4 0.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) RVT_1 PF00078.22 OAJ02030.1 - 8.5e-16 57.9 0.0 1.8e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02030.1 - 1.1e-13 51.3 0.0 7.7e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ02030.1 - 0.0026 18.2 0.0 0.0089 16.5 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ02030.1 - 0.0096 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RasGAP PF00616.14 OAJ02032.1 - 0.14 11.8 1.8 0.18 11.4 1.2 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF2422 PF10337.4 OAJ02032.1 - 0.23 10.2 3.7 0.27 9.9 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) SpoIIIAH PF12685.2 OAJ02032.1 - 0.38 10.2 7.2 0.43 10.0 5.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3154 PF11351.3 OAJ02032.1 - 0.54 10.0 6.3 0.99 9.1 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Adeno_VII PF03228.9 OAJ02032.1 - 2.7 8.6 6.7 4.1 8.0 4.6 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII DUF3682 PF12446.3 OAJ02034.1 - 0.066 13.5 0.7 0.082 13.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Transglut_prok PF09017.5 OAJ02034.1 - 0.11 11.6 0.5 0.11 11.6 0.3 1.0 1 0 0 1 1 1 0 Microbial transglutaminase AT_hook PF02178.14 OAJ02034.1 - 6.7 6.7 11.3 2.3 8.1 5.2 2.4 2 1 0 2 2 2 0 AT hook motif RVT_1 PF00078.22 OAJ02036.1 - 1.9e-10 40.4 0.0 5.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FHA PF00498.21 OAJ02037.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-MYND PF01753.13 OAJ02038.1 - 0.00063 19.5 1.5 0.002 17.9 1.0 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 OAJ02038.1 - 0.0022 17.2 2.6 0.0043 16.3 1.8 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF2116 PF09889.4 OAJ02038.1 - 0.22 11.3 1.4 0.46 10.3 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4348 PF14254.1 OAJ02038.1 - 0.74 8.8 1.2 1.3 8.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4348) Pkinase PF00069.20 OAJ02039.1 - 6.5e-46 156.5 0.0 6e-45 153.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02039.1 - 5.5e-22 78.0 0.0 1.4e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 OAJ02039.1 - 0.0032 16.5 0.4 0.0061 15.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ02039.1 - 0.29 10.0 0.0 1.3 7.9 0.0 1.8 2 0 0 2 2 2 0 Kinase-like FMN_red PF03358.10 OAJ02041.1 - 1.4e-08 34.3 0.0 2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 OAJ02041.1 - 2.6e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_4 PF12682.2 OAJ02041.1 - 0.017 14.5 0.0 0.039 13.2 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin SNF2_N PF00176.18 OAJ02043.1 - 4.8e-72 242.2 0.1 8.4e-72 241.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ02043.1 - 6.3e-13 48.3 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ02043.1 - 1e-09 38.0 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 OAJ02043.1 - 4e-07 29.5 3.4 4e-07 29.5 2.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ02043.1 - 4.8e-07 29.7 4.7 4.8e-07 29.7 3.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 OAJ02043.1 - 6.2e-07 29.4 0.0 6.2e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 OAJ02043.1 - 1.4e-05 24.8 6.1 1.4e-05 24.8 4.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ02043.1 - 2.2e-05 24.2 4.9 2.2e-05 24.2 3.4 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ02043.1 - 2.2e-05 24.0 4.8 2.2e-05 24.0 3.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ02043.1 - 8.9e-05 22.1 4.6 8.9e-05 22.1 3.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ02043.1 - 0.00089 18.9 0.5 0.00089 18.9 0.3 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 OAJ02043.1 - 0.0012 18.5 3.1 0.0028 17.4 2.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein HTH_3 PF01381.17 OAJ02043.1 - 0.0056 16.4 0.1 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix zf-Nse PF11789.3 OAJ02043.1 - 0.11 12.0 1.5 0.29 10.6 1.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Helicase_C_2 PF13307.1 OAJ02044.1 - 7.3e-53 178.9 0.0 1.8e-52 177.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 OAJ02044.1 - 3e-41 140.7 0.0 9e-41 139.1 0.0 1.8 1 1 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 OAJ02044.1 - 0.0004 20.5 0.3 1.4 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 OAJ02044.1 - 0.0047 16.1 0.1 0.69 9.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 OAJ02044.1 - 0.06 13.1 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TPR_11 PF13414.1 OAJ02050.1 - 5.4e-26 90.0 1.1 7e-13 48.0 0.0 3.8 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ02050.1 - 4.9e-19 67.0 0.1 4.1e-05 23.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02050.1 - 2.4e-13 48.8 5.7 0.00063 19.4 0.0 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02050.1 - 7.9e-12 44.3 0.8 0.0074 16.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ02050.1 - 4.3e-11 42.6 5.7 2.4e-06 27.3 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02050.1 - 6.2e-11 41.9 6.9 0.011 16.2 0.0 6.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ02050.1 - 4.3e-10 38.6 0.0 0.028 14.2 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ02050.1 - 2.3e-09 37.6 0.2 0.00021 21.8 0.0 6.4 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ02050.1 - 1.6e-07 31.5 0.9 0.15 12.4 0.0 4.8 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ02050.1 - 2.2e-06 27.0 0.0 0.25 11.1 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ02050.1 - 0.00078 19.2 4.5 0.71 9.7 0.0 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ02050.1 - 0.0035 17.4 8.1 0.076 13.1 0.3 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat Peptidase_M14 PF00246.19 OAJ02051.1 - 1.3e-54 185.7 0.0 2.7e-53 181.3 0.0 2.6 2 1 0 2 2 2 1 Zinc carboxypeptidase ATP11 PF06644.6 OAJ02052.1 - 1.1e-65 221.7 0.0 2e-65 220.9 0.0 1.4 1 1 0 1 1 1 1 ATP11 protein Ribosomal_L27e PF01777.13 OAJ02053.1 - 4.8e-38 129.1 1.0 7.5e-38 128.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 OAJ02053.1 - 0.00019 20.9 0.5 0.0004 20.0 0.3 1.5 1 0 0 1 1 1 1 KOW motif Sel1 PF08238.7 OAJ02054.1 - 4.8e-21 74.6 27.0 1.8e-05 25.2 0.1 8.7 9 0 0 9 9 9 4 Sel1 repeat TPR_11 PF13414.1 OAJ02054.1 - 5.2e-06 26.0 1.2 0.15 11.6 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.1 OAJ02054.1 - 0.0036 17.6 3.7 2.1 8.9 0.1 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ02054.1 - 0.0053 16.6 0.7 1.6 8.7 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02054.1 - 0.8 9.7 0.0 0.8 9.7 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 OAJ02056.1 - 1.1e-16 61.2 0.0 2e-16 60.3 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ02056.1 - 1.7e-06 28.1 0.0 2.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily POT1 PF02765.12 OAJ02057.1 - 4.4e-10 39.6 0.0 8.8e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 zf-ribbon_3 PF13248.1 OAJ02057.1 - 0.0023 17.0 3.5 0.0048 16.0 2.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 OAJ02057.1 - 0.0036 16.7 2.6 0.0077 15.6 1.8 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 OAJ02057.1 - 0.027 14.2 0.6 0.068 12.9 0.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-DHHC PF01529.15 OAJ02058.1 - 9.5e-30 103.2 0.0 1.5e-28 99.3 0.0 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2051 PF09738.4 OAJ02058.1 - 0.37 10.0 3.8 0.15 11.3 0.9 1.5 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) EF-hand_6 PF13405.1 OAJ02059.1 - 3.1e-09 35.9 2.9 0.00011 21.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 OAJ02059.1 - 7.4e-09 35.6 1.2 9.6e-07 28.8 0.8 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ02059.1 - 5.3e-08 31.6 5.9 0.00029 19.9 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 OAJ02059.1 - 0.0024 17.1 2.9 0.031 13.6 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 OAJ02059.1 - 0.63 9.6 3.8 15 5.2 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair ERCC4 PF02732.10 OAJ02060.1 - 0.06 13.1 0.0 0.21 11.3 0.0 2.0 1 1 0 1 1 1 0 ERCC4 domain LMBR1 PF04791.11 OAJ02060.1 - 0.12 10.8 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 OAJ02060.1 - 0.29 11.4 5.3 0.51 10.6 3.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleo_P87 PF07267.6 OAJ02060.1 - 0.46 9.1 5.2 0.87 8.1 3.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF936 PF06075.7 OAJ02060.1 - 0.97 8.2 17.5 1.7 7.4 12.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) RNase_H2-Ydr279 PF09468.5 OAJ02060.1 - 1.6 7.8 8.7 2.5 7.2 6.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Neur_chan_memb PF02932.11 OAJ02060.1 - 3.3 7.5 4.6 32 4.2 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFR_dimer PF04253.10 OAJ02061.1 - 1.8e-15 56.6 0.0 3.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 OAJ02061.1 - 9.3e-13 48.3 0.7 1.5e-12 47.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 OAJ02061.1 - 2.2e-05 24.0 0.1 5.4e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 PA domain YbaJ PF10757.4 OAJ02061.1 - 0.14 12.3 0.2 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ tRNA-synt_2 PF00152.15 OAJ02063.1 - 9.3e-85 284.3 0.0 1.1e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ02063.1 - 2.5e-11 43.2 0.0 9.9e-11 41.3 0.0 2.1 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ02063.1 - 4.4e-08 32.6 0.1 8.6e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 OAJ02063.1 - 0.0057 16.2 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_M28 PF04389.12 OAJ02064.1 - 1.9e-13 50.5 0.0 3.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 OAJ02064.1 - 2.4e-09 36.7 0.1 5.6e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 PA domain TFR_dimer PF04253.10 OAJ02064.1 - 1.8e-06 27.5 0.0 1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Transferrin receptor-like dimerisation domain Actin PF00022.14 OAJ02065.1 - 1.3e-48 165.3 0.0 6.5e-48 163.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ02065.1 - 0.0085 14.7 0.0 0.026 13.1 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein UDPGP PF01704.13 OAJ02066.1 - 1.1e-17 63.6 0.0 4.3e-17 61.7 0.0 1.6 1 1 1 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase SKIP_SNW PF02731.10 OAJ02067.1 - 1.9e-64 215.9 1.2 1.9e-64 215.9 0.8 2.1 3 0 0 3 3 3 1 SKIP/SNW domain MFS_1 PF07690.11 OAJ02068.1 - 3.2e-23 82.0 44.5 3.2e-13 49.1 21.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 OAJ02068.1 - 0.2 9.6 6.4 0.076 11.0 0.5 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATE_C PF04377.10 OAJ02069.1 - 1.2e-41 141.7 0.1 1.8e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 OAJ02069.1 - 1.7e-22 79.0 0.4 3.2e-22 78.1 0.3 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Glyco_transf_8 PF01501.15 OAJ02070.1 - 2.7e-23 82.6 0.0 6.4e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 Abhydrolase_6 PF12697.2 OAJ02070.1 - 1.1e-21 77.7 0.0 6.8e-21 75.2 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ02070.1 - 1.1e-15 57.6 0.0 2.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ02070.1 - 4.5e-15 55.2 0.0 1.3e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ02070.1 - 0.00025 20.6 0.2 0.0035 16.9 0.1 2.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Mannosyl_trans3 PF11051.3 OAJ02070.1 - 0.00027 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Esterase PF00756.15 OAJ02070.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 OAJ02070.1 - 0.0032 16.5 0.0 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 OAJ02070.1 - 0.0038 16.4 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 OAJ02070.1 - 0.026 14.0 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 OAJ02070.1 - 0.03 13.9 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) PGAP1 PF07819.8 OAJ02070.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.10 OAJ02070.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase BCA_ABC_TP_C PF12399.3 OAJ02070.1 - 0.11 12.2 1.1 2.6 7.8 0.1 2.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DUF2305 PF10230.4 OAJ02070.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) PX PF00787.19 OAJ02071.1 - 1.6e-21 76.1 0.7 4.3e-21 74.8 0.5 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 OAJ02071.1 - 4.8e-07 29.2 4.7 0.032 13.4 0.1 3.6 4 0 0 4 4 4 3 Vps5 C terminal like BAR PF03114.13 OAJ02071.1 - 0.002 17.6 1.2 1.6 8.1 0.0 3.2 3 0 0 3 3 3 2 BAR domain APC2 PF08672.6 OAJ02071.1 - 0.013 15.7 0.1 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Dynamitin PF04912.9 OAJ02071.1 - 0.048 12.4 0.2 0.094 11.4 0.1 1.4 1 0 0 1 1 1 0 Dynamitin RFX_DNA_binding PF02257.10 OAJ02072.1 - 3.5e-16 59.1 0.0 6.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain Rep_fac-A_3 PF08661.6 OAJ02073.1 - 5.7e-28 96.9 0.1 6.3e-28 96.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Cyto_heme_lyase PF01265.12 OAJ02074.1 - 3.5e-74 249.6 0.0 4.6e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Hamartin PF04388.7 OAJ02075.1 - 1.5e-17 63.5 0.0 1.5e-17 63.5 0.0 3.5 2 1 1 3 3 3 1 Hamartin protein Aminotran_4 PF01063.14 OAJ02075.1 - 1.2e-06 28.2 2.9 6.4e-06 25.7 0.0 3.2 2 1 0 2 2 2 1 Aminotransferase class IV RecO_N PF11967.3 OAJ02075.1 - 0.12 12.1 0.1 0.95 9.3 0.0 2.3 2 0 0 2 2 2 0 Recombination protein O N terminal Phlebovirus_NSM PF07246.6 OAJ02075.1 - 3 6.9 8.2 2 7.5 3.4 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M tRNA-synt_2 PF00152.15 OAJ02076.1 - 5.2e-69 232.5 0.0 7.5e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ02076.1 - 7.8e-11 41.6 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRP7 PF12923.2 OAJ02076.1 - 0.024 14.6 3.7 0.047 13.7 2.6 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DPM3 PF08285.6 OAJ02079.1 - 1.7e-26 91.8 0.0 1.9e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Transketolase_N PF00456.16 OAJ02081.1 - 1.9e-16 59.7 2.8 9.3e-15 54.2 1.9 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 OAJ02081.1 - 2.4e-11 43.6 0.1 7.8e-11 41.9 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 OAJ02081.1 - 0.0001 21.8 0.1 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 OAJ02081.1 - 0.088 12.3 0.0 0.32 10.5 0.0 2.0 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 OAJ02081.1 - 0.1 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Complex1_LYR PF05347.10 OAJ02082.1 - 8.7e-08 31.8 0.4 1.6e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ02082.1 - 1.6e-07 31.3 1.4 1.7e-07 31.3 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAJ02082.1 - 0.064 13.7 0.7 0.085 13.3 0.5 1.2 1 0 0 1 1 1 0 Complex1_LYR-like TIMELESS PF04821.9 OAJ02083.1 - 9.5e-41 139.8 0.1 9.5e-41 139.8 0.0 3.3 2 1 0 2 2 2 1 Timeless protein Pkinase PF00069.20 OAJ02085.1 - 1e-24 87.0 0.0 2e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02085.1 - 2.4e-05 23.5 0.0 4.8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ02085.1 - 0.0088 15.1 0.0 0.035 13.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ02085.1 - 0.0092 15.7 0.1 0.055 13.1 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ02085.1 - 0.018 14.0 0.0 0.046 12.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RasGEF PF00617.14 OAJ02087.1 - 1.6e-43 148.6 0.0 3.3e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ02087.1 - 1.1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 OAJ02087.1 - 2.7e-14 52.4 0.1 6e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ02087.1 - 3.8e-14 51.9 0.1 8.2e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ02087.1 - 4.4e-13 48.3 0.0 7.9e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Miff PF05644.6 OAJ02087.1 - 0.017 14.7 0.1 0.065 12.8 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff PI3Ka PF00613.15 OAJ02089.1 - 3.9e-52 176.1 0.0 6.2e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 OAJ02089.1 - 6.1e-34 116.8 0.0 1.1e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.22 OAJ02089.1 - 4e-31 108.2 0.0 3.4e-24 85.6 0.0 3.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase C2 PF00168.25 OAJ02089.1 - 0.0048 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain KH_1 PF00013.24 OAJ02091.1 - 9.6e-40 134.0 12.6 5e-16 58.0 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 OAJ02091.1 - 9.7e-30 101.7 12.1 1.2e-10 40.7 1.7 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 OAJ02091.1 - 1.4e-09 37.3 9.7 0.0028 17.1 0.2 3.5 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 OAJ02091.1 - 2.3e-08 33.5 0.8 0.067 12.8 0.0 3.4 3 0 0 3 3 3 3 KH domain dUTPase PF00692.14 OAJ02091.1 - 0.02 14.3 1.1 0.15 11.5 0.1 2.6 3 0 0 3 3 3 0 dUTPase KH_5 PF13184.1 OAJ02091.1 - 0.025 14.3 5.4 1.4 8.7 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain DUF202 PF02656.10 OAJ02092.1 - 2.7e-14 53.1 1.8 4.5e-14 52.4 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) tRNA-synt_2b PF00587.20 OAJ02093.1 - 3e-17 62.7 0.0 1.7e-16 60.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) AATF-Che1 PF13339.1 OAJ02093.1 - 0.034 14.2 0.2 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor eIF-1a PF01176.14 OAJ02095.1 - 5.8e-28 96.1 0.1 8.2e-28 95.6 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ATG_C PF09333.6 OAJ02096.1 - 7.4e-27 93.3 1.5 7.1e-26 90.2 0.1 3.2 4 0 0 4 4 4 1 ATG C terminal domain Chorein_N PF12624.2 OAJ02096.1 - 1.7e-07 30.7 0.0 0.00092 18.7 0.0 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 OAJ02096.1 - 0.0019 17.8 0.0 0.019 14.5 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Fib_alpha PF08702.5 OAJ02096.1 - 0.057 13.5 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HhH-GPD PF00730.20 OAJ02098.1 - 2.2e-10 40.7 0.0 4.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SSF PF00474.12 OAJ02100.1 - 3.4e-22 78.6 27.5 5.9e-22 77.8 19.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Cytochrom_B561 PF03188.11 OAJ02101.1 - 8.4e-09 35.3 12.4 1.8e-08 34.2 8.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ02101.1 - 0.00042 20.2 0.7 0.00077 19.3 0.2 1.5 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 OAJ02101.1 - 3.4 7.2 8.5 7.6 6.1 4.6 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF2427) ACBP PF00887.14 OAJ02102.1 - 6.8e-27 92.9 0.0 1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Nucleoplasmin PF03066.10 OAJ02102.1 - 0.0051 16.3 11.1 0.01 15.3 7.7 1.5 1 0 0 1 1 1 1 Nucleoplasmin DUF4366 PF14283.1 OAJ02102.1 - 0.0091 15.4 2.6 0.014 14.7 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Daxx PF03344.10 OAJ02102.1 - 0.016 13.7 13.7 0.022 13.2 9.5 1.0 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 OAJ02102.1 - 0.075 12.7 11.8 0.11 12.2 8.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.13 OAJ02102.1 - 0.24 10.5 5.8 0.4 9.7 4.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SGT1 PF07093.6 OAJ02102.1 - 0.69 8.2 5.3 0.91 7.8 3.6 1.1 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 OAJ02102.1 - 0.94 7.3 14.5 1.3 6.8 10.0 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ02102.1 - 1.8 7.7 13.8 2.7 7.1 9.6 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 OAJ02102.1 - 2.9 7.0 10.2 4.2 6.5 7.1 1.1 1 0 0 1 1 1 0 SDA1 PBP1_TM PF14812.1 OAJ02102.1 - 3.4 8.0 18.2 8 6.8 12.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 OAJ02102.1 - 3.7 7.0 10.2 5.3 6.5 7.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.8 OAJ02102.1 - 7.3 6.1 16.9 13 5.3 11.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Seryl_tRNA_N PF02403.17 OAJ02105.1 - 0.18 11.8 2.9 8.2 6.4 0.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fork_head PF00250.13 OAJ02106.1 - 7.7e-10 38.6 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Mito_fiss_reg PF05308.6 OAJ02106.1 - 3.8 6.7 5.5 9.8 5.4 3.8 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator CDO_I PF05995.7 OAJ02107.1 - 3.2e-05 23.1 0.3 5.9e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 OAJ02107.1 - 0.00011 21.5 1.1 0.0003 20.1 0.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1637) DUF772 PF05598.6 OAJ02107.1 - 0.16 11.8 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Transposase domain (DUF772) Cellulase PF00150.13 OAJ02108.1 - 8.8e-10 38.2 0.0 9.6e-06 24.9 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) eIF-5_eIF-2B PF01873.12 OAJ02109.1 - 3.6e-41 139.7 0.1 5.7e-41 139.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 OAJ02109.1 - 3.3e-21 75.0 0.6 1.4e-20 72.9 0.2 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Pro_isomerase PF00160.16 OAJ02110.1 - 9.4e-17 61.6 0.0 1.4e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med26 PF08711.6 OAJ02111.1 - 6.7e-10 38.3 0.0 1.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LMBR1 PF04791.11 OAJ02111.1 - 0.54 8.7 1.0 0.73 8.3 0.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF974 PF06159.8 OAJ02112.1 - 2.4e-39 135.2 0.0 4e-31 108.3 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF974) Transglut_C PF00927.17 OAJ02112.1 - 0.018 15.0 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Nop14 PF04147.7 OAJ02113.1 - 4 5.2 5.7 5.3 4.8 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1757 PF08560.5 OAJ02114.1 - 0.048 13.3 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) TctB PF07331.6 OAJ02114.1 - 0.088 12.4 1.6 0.17 11.5 0.5 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family TFIIA PF03153.8 OAJ02116.1 - 8.2 6.2 10.0 11 5.7 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.4 OAJ02117.1 - 1.5e-20 73.4 0.0 6.7e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase OPT PF03169.10 OAJ02118.1 - 1.3e-171 572.2 56.5 1.6e-171 571.9 39.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Daxx PF03344.10 OAJ02118.1 - 7.5 4.8 5.7 12 4.2 3.9 1.2 1 0 0 1 1 1 0 Daxx Family R3H PF01424.17 OAJ02119.1 - 6.7e-12 44.9 0.8 2.4e-11 43.1 0.1 2.1 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 OAJ02119.1 - 8.1e-10 38.5 0.1 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ02119.1 - 1.4e-06 27.7 0.0 3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02119.1 - 4.3e-06 26.4 0.1 8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.13 OAJ02120.1 - 3.6e-22 77.6 0.1 1e-21 76.1 0.0 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 OAJ02120.1 - 0.00082 19.1 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Striatin PF08232.7 OAJ02121.1 - 3.2e-43 147.2 0.7 3.2e-43 147.2 0.5 5.0 5 1 0 5 5 5 1 Striatin family WD40 PF00400.27 OAJ02121.1 - 8e-37 123.8 10.0 2.8e-07 30.1 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat adh_short PF00106.20 OAJ02122.1 - 4.6e-25 88.4 0.2 5.7e-25 88.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ02122.1 - 3.3e-21 76.1 0.0 4.1e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ02122.1 - 8.4e-11 41.8 0.1 1.1e-10 41.5 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 OAJ02122.1 - 0.0024 17.0 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 OAJ02122.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CW_binding_2 PF04122.7 OAJ02122.1 - 0.088 13.0 0.3 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 FimP PF09766.4 OAJ02123.1 - 0.22 10.5 18.2 0.058 12.4 6.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Neur_chan_memb PF02932.11 OAJ02123.1 - 0.55 10.0 5.5 1.2 8.9 0.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.3 OAJ02123.1 - 1.3 8.3 13.6 3.6 6.8 5.3 2.2 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 OAJ02123.1 - 4.1 7.0 17.7 3.2 7.3 6.6 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BRF1 PF07741.8 OAJ02123.1 - 4.2 7.6 11.0 0.55 10.4 3.2 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DivIC PF04977.10 OAJ02123.1 - 5.1 6.6 21.4 2.2 7.8 8.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Band_3_cyto PF07565.8 OAJ02123.1 - 9.2 5.6 14.2 16 4.8 6.1 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2347 PF09804.4 OAJ02123.1 - 9.3 5.4 9.8 13 5.0 3.7 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) TauD PF02668.11 OAJ02125.1 - 1e-52 179.3 0.1 1.7e-52 178.6 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AMP-binding PF00501.23 OAJ02126.1 - 9.5e-75 251.5 0.0 1.6e-74 250.8 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme DUF2462 PF09495.5 OAJ02127.1 - 1.3e-15 57.8 13.1 1.5e-15 57.7 8.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) MSA-2c PF12238.3 OAJ02127.1 - 0.15 11.7 4.4 0.16 11.5 3.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c BORG_CEP PF14957.1 OAJ02127.1 - 0.21 12.5 2.7 0.22 12.4 1.8 1.2 1 0 0 1 1 1 0 Cdc42 effector RVT_3 PF13456.1 OAJ02128.1 - 0.0009 18.9 0.0 0.0037 17.0 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase-like Kelch_4 PF13418.1 OAJ02133.1 - 0.39 10.5 18.0 12 5.7 0.3 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Rad51 PF08423.6 OAJ02137.1 - 0.013 14.3 0.0 2.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Rad51 AAA_25 PF13481.1 OAJ02137.1 - 0.034 13.5 0.2 8.9 5.6 0.3 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAJ02138.1 - 2.3e-16 60.3 0.1 9.7e-13 48.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ02138.1 - 2.2e-08 34.4 1.2 0.0021 18.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 OAJ02138.1 - 3.1e-06 27.0 0.1 0.0093 15.8 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 OAJ02138.1 - 0.0015 18.9 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ02138.1 - 0.0017 17.8 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ02138.1 - 0.015 14.7 0.3 0.073 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ02138.1 - 0.019 14.6 0.0 0.066 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 OAJ02138.1 - 0.052 13.5 2.5 0.12 12.3 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 OAJ02138.1 - 0.054 12.7 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SE PF00437.15 OAJ02138.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.1 OAJ02138.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 OAJ02138.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DAP3 PF10236.4 OAJ02138.1 - 0.12 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 OAJ02138.1 - 0.12 12.0 0.1 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 OAJ02138.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 OAJ02138.1 - 0.2 11.1 0.2 0.34 10.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AMPKBI PF04739.10 OAJ02139.1 - 3e-26 91.2 0.0 6.1e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain SNF2_N PF00176.18 OAJ02140.1 - 1.2e-65 221.3 0.3 1.7e-65 220.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ02140.1 - 1.6e-09 37.5 0.0 6e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 OAJ02140.1 - 9.1e-06 25.3 0.9 2.2e-05 24.0 0.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ02140.1 - 0.00017 21.5 1.7 0.00017 21.5 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ02140.1 - 0.00054 19.5 1.5 0.00054 19.5 1.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ02140.1 - 0.00092 18.9 1.3 0.0021 17.8 0.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ02140.1 - 0.0017 17.9 2.8 0.0053 16.3 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ02140.1 - 0.014 15.0 0.1 0.033 13.8 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Daxx PF03344.10 OAJ02140.1 - 0.61 8.5 41.7 0.52 8.7 8.0 2.6 2 0 0 2 2 2 0 Daxx Family zf-C3HC4_4 PF15227.1 OAJ02140.1 - 0.87 9.5 6.0 0.19 11.6 1.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Chitin_synth_1 PF01644.12 OAJ02142.1 - 3.8e-69 231.6 1.6 6e-69 231.0 1.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 OAJ02142.1 - 7.9e-23 80.6 0.0 3.5e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 OAJ02142.1 - 8.7e-19 66.9 0.1 1.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 OAJ02142.1 - 1.9e-09 37.4 0.5 1.9e-09 37.4 0.3 2.9 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ02142.1 - 3.7e-08 33.4 0.0 9.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-C2H2 PF00096.21 OAJ02143.1 - 3.8e-06 26.9 18.9 5.2e-05 23.3 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ02143.1 - 5.9e-05 23.1 2.1 5.9e-05 23.1 1.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 OAJ02143.1 - 0.0026 17.9 0.9 0.0026 17.9 0.6 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 OAJ02143.1 - 0.0029 17.7 2.6 0.043 14.0 0.1 3.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAJ02143.1 - 0.013 15.6 0.1 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 OAJ02143.1 - 0.37 10.5 2.1 0.8 9.4 1.0 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_1 PF07690.11 OAJ02145.1 - 9.5e-32 110.0 24.7 9.5e-32 110.0 17.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Chromo PF00385.19 OAJ02146.1 - 2.6e-07 30.1 0.4 5.9e-07 29.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ST7 PF04184.7 OAJ02146.1 - 2.7 6.1 0.5 4 5.5 0.3 1.1 1 0 0 1 1 1 0 ST7 protein RVT_1 PF00078.22 OAJ02148.1 - 1.2e-21 77.1 0.0 1.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Neur_chan_memb PF02932.11 OAJ02149.1 - 0.014 15.2 0.1 0.038 13.8 0.1 1.9 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDE_Tnp_4 PF13359.1 OAJ02150.1 - 7.3e-23 80.9 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_3 PF01381.17 OAJ02150.1 - 0.43 10.4 3.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix MFS_1 PF07690.11 OAJ02151.1 - 3.8e-32 111.3 17.6 3.8e-32 111.3 12.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily XPG_I PF00867.13 OAJ02153.1 - 3.2e-09 36.7 0.0 8.3e-08 32.1 0.0 2.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 OAJ02153.1 - 0.00069 19.8 0.0 0.0033 17.6 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_N PF00752.12 OAJ02153.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain DUF605 PF04652.11 OAJ02154.1 - 0.47 9.8 6.5 0.75 9.1 4.5 1.2 1 0 0 1 1 1 0 Vta1 like MAM33 PF02330.11 OAJ02158.1 - 9.4e-32 110.4 0.0 1.6e-31 109.6 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial glycoprotein AdoHcyase PF05221.12 OAJ02158.1 - 0.042 12.8 0.2 0.069 12.0 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase PH PF00169.24 OAJ02160.1 - 4.4e-09 36.4 0.0 1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4414 PF14377.1 OAJ02161.1 - 2.2 8.2 6.2 2.8 7.8 3.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4414) G-patch PF01585.18 OAJ02162.1 - 1.6e-13 50.1 1.7 3.8e-13 48.9 1.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 OAJ02162.1 - 9.4e-05 22.1 0.5 9.4e-05 22.1 0.3 3.8 2 1 0 3 3 3 1 DExH-box splicing factor binding site TFIIF_alpha PF05793.7 OAJ02162.1 - 0.0016 16.9 33.5 0.0022 16.4 23.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 OAJ02162.1 - 0.006 15.1 17.5 0.0077 14.7 12.1 1.3 1 0 0 1 1 1 1 Daxx Family Mem_trans PF03547.13 OAJ02162.1 - 0.91 7.7 3.3 1.3 7.2 2.3 1.3 1 0 0 1 1 1 0 Membrane transport protein SOBP PF15279.1 OAJ02162.1 - 2.7 8.2 21.1 3.9 7.7 14.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ebola_NP PF05505.7 OAJ02162.1 - 2.8 5.9 14.5 3.1 5.7 10.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein BSMAP PF12280.3 OAJ02162.1 - 4 7.2 9.3 7.4 6.4 6.4 1.5 1 0 0 1 1 1 0 Brain specific membrane anchored protein Hid1 PF12722.2 OAJ02162.1 - 6.3 4.3 17.8 8.1 3.9 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.14 OAJ02162.1 - 6.8 5.2 13.2 10 4.6 9.2 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Parvo_coat PF00740.13 OAJ02162.1 - 7.8 5.3 9.6 11 4.8 6.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CDC27 PF09507.5 OAJ02162.1 - 8.4 5.4 44.5 0.29 10.3 25.3 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Lyase_aromatic PF00221.14 OAJ02163.1 - 5.5e-157 523.0 5.5 7.6e-157 522.5 3.8 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase APG6 PF04111.7 OAJ02164.1 - 8.8e-103 343.6 0.5 1.1e-102 343.3 0.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF972 PF06156.8 OAJ02164.1 - 0.012 15.9 3.7 0.014 15.7 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HAUS-augmin3 PF14932.1 OAJ02164.1 - 0.06 12.5 11.0 0.095 11.8 7.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TBPIP PF07106.8 OAJ02164.1 - 0.084 12.4 5.9 0.15 11.5 4.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 OAJ02164.1 - 0.086 10.6 3.7 0.12 10.2 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C4H2 PF10146.4 OAJ02164.1 - 0.25 11.3 7.5 0.47 10.4 5.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DASH_Dad3 PF08656.5 OAJ02164.1 - 0.84 9.3 5.7 3.1 7.5 0.7 2.7 1 1 0 2 2 2 0 DASH complex subunit Dad3 IncA PF04156.9 OAJ02164.1 - 1.8 8.1 12.8 3.3 7.2 8.9 1.4 1 0 0 1 1 1 0 IncA protein SPC22 PF04573.7 OAJ02165.1 - 2.2e-44 150.7 0.2 2.5e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DEAD PF00270.24 OAJ02172.1 - 1.1e-46 158.3 0.0 1.9e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ02172.1 - 1.1e-26 92.5 0.0 2.3e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02172.1 - 0.02 14.7 0.0 0.054 13.3 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Transferase PF02458.10 OAJ02173.1 - 1.7e-08 33.3 0.0 0.006 15.0 0.0 2.8 3 0 0 3 3 3 2 Transferase family Condensation PF00668.15 OAJ02173.1 - 0.014 14.2 0.0 0.21 10.3 0.0 2.2 2 0 0 2 2 2 0 Condensation domain Rotavirus_VP1 PF12289.3 OAJ02173.1 - 0.052 13.1 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Rotavirus VP1 structural protein BRCT PF00533.21 OAJ02174.1 - 9e-10 38.5 0.1 4.6e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 OAJ02174.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Mcm10 PF09332.6 OAJ02174.1 - 0.93 8.7 8.8 0.21 10.8 3.9 1.5 2 0 0 2 2 2 0 Mcm10 replication factor Arm PF00514.18 OAJ02175.1 - 1.1e-78 256.6 9.3 3.7e-11 42.4 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ02175.1 - 5.1e-23 81.1 6.5 8.7e-08 32.3 0.2 5.8 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 OAJ02175.1 - 1.8e-19 69.6 7.4 2.9e-07 30.7 0.0 6.1 4 3 3 7 7 7 5 HEAT-like repeat HEAT PF02985.17 OAJ02175.1 - 4.3e-16 57.4 5.5 0.0014 18.5 0.0 7.6 8 0 0 8 8 8 4 HEAT repeat IBB PF01749.15 OAJ02175.1 - 1.9e-11 43.9 0.4 3.7e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain RICTOR_V PF14668.1 OAJ02175.1 - 4.7e-05 23.2 0.3 0.24 11.3 0.0 3.3 3 1 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 OAJ02175.1 - 0.0016 18.7 0.1 2.9 8.5 0.0 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.15 OAJ02175.1 - 0.044 12.0 0.0 0.21 9.8 0.0 2.1 1 1 0 1 1 1 0 Adaptin N terminal region G-alpha PF00503.15 OAJ02177.1 - 5.1e-134 446.8 1.2 6.3e-134 446.5 0.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ02177.1 - 6.1e-17 61.4 0.5 7.9e-12 44.7 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ02177.1 - 8.4e-05 21.8 1.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ02177.1 - 0.00045 20.6 0.1 0.62 10.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein zf-CHC2 PF01807.15 OAJ02177.1 - 0.0022 17.5 0.0 0.0077 15.7 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger AAA_29 PF13555.1 OAJ02177.1 - 0.0058 16.1 0.2 0.039 13.4 0.1 2.2 1 1 1 2 2 2 1 P-loop containing region of AAA domain MCM PF00493.18 OAJ02177.1 - 0.0094 14.7 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MMR_HSR1 PF01926.18 OAJ02177.1 - 0.013 15.4 0.1 0.39 10.6 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 OAJ02177.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_15 PF13175.1 OAJ02177.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 OAJ02177.1 - 0.063 12.7 0.0 2.5 7.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 OAJ02177.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Glyco_transf_41 PF13844.1 OAJ02178.1 - 7.9e-97 324.1 0.4 2.9e-44 150.8 0.0 4.1 4 0 0 4 4 4 4 Glycosyl transferase family 41 TPR_11 PF13414.1 OAJ02178.1 - 2.9e-24 84.5 0.5 1.6e-09 37.2 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ02178.1 - 2.5e-19 67.9 0.0 5.6e-05 22.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02178.1 - 6.2e-18 63.4 3.4 2.6e-05 24.0 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02178.1 - 4.2e-15 54.3 0.1 0.0018 18.0 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ02178.1 - 7.2e-13 48.2 0.3 1.3e-05 25.0 0.0 4.8 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02178.1 - 2.6e-12 46.1 0.0 0.013 16.1 0.0 5.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ02178.1 - 6e-12 44.4 0.0 0.0034 17.0 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ02178.1 - 5e-07 29.4 1.8 0.06 13.2 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ02178.1 - 1.4e-06 28.5 0.0 0.41 11.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ02178.1 - 6.6e-06 25.5 0.0 0.17 11.7 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ02178.1 - 0.0037 17.6 0.0 15 6.3 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.13 OAJ02179.1 - 4.5e-35 119.6 5.1 2.9e-08 33.7 0.1 6.2 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ02179.1 - 7.7e-22 76.3 8.5 4.1e-05 23.0 0.1 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 OAJ02179.1 - 1.1e-10 41.0 9.9 1.1e-10 41.0 6.9 1.6 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 OAJ02179.1 - 0.001 18.7 3.6 0.001 18.7 2.5 2.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 OAJ02179.1 - 0.0094 15.2 0.9 0.0094 15.2 0.6 1.9 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 OAJ02179.1 - 0.73 9.6 9.9 0.83 9.4 3.8 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 OAJ02179.1 - 1.3 8.8 10.0 4.9 7.0 7.0 1.9 1 1 0 1 1 1 0 Ring finger domain PapC_C PF13953.1 OAJ02179.1 - 1.5 8.5 3.9 4.3 7.0 0.0 3.3 4 0 0 4 4 4 0 PapC C-terminal domain UPF0220 PF05255.6 OAJ02181.1 - 2.2e-51 173.3 0.0 2.9e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) CHCH PF06747.8 OAJ02182.1 - 1.2e-07 31.3 4.5 2.3e-07 30.5 3.1 1.5 1 0 0 1 1 1 1 CHCH domain PQQ_2 PF13360.1 OAJ02182.1 - 0.055 12.9 0.9 0.084 12.3 0.6 1.3 1 0 0 1 1 1 0 PQQ-like domain GCK PF07802.6 OAJ02182.1 - 0.062 13.4 3.9 0.12 12.5 2.7 1.4 1 0 0 1 1 1 0 GCK domain Pyridoxal_deC PF00282.14 OAJ02183.1 - 2.3e-22 78.9 0.0 3.2e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ02183.1 - 7.6e-11 41.3 0.0 1.7e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 OAJ02183.1 - 0.0077 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AhpC-TSA_2 PF13911.1 OAJ02184.1 - 2.3e-15 56.5 0.0 3.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ02184.1 - 0.0072 15.8 0.0 0.042 13.3 0.0 1.9 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 OAJ02184.1 - 0.014 15.1 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA family Saccharop_dh PF03435.13 OAJ02185.1 - 5.3e-12 45.4 0.0 1.4e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase RVT_1 PF00078.22 OAJ02190.1 - 5.2e-19 68.4 0.0 9.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02190.1 - 6.8e-16 58.4 0.0 2.2e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ02190.1 - 4.8e-05 23.7 0.2 0.00014 22.2 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ02190.1 - 0.00084 19.2 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ02190.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAJ02191.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein PAT1 PF09770.4 OAJ02191.1 - 0.21 9.7 8.9 0.3 9.2 6.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FUSC PF04632.7 OAJ02191.1 - 0.42 8.9 8.6 0.54 8.6 1.8 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Mif2_N PF15624.1 OAJ02191.1 - 6.5 7.3 17.6 0.077 13.5 0.5 3.3 3 0 0 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Histone PF00125.19 OAJ02192.1 - 2.2e-21 75.7 0.1 3.1e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ02192.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ATP_bind_1 PF03029.12 OAJ02193.1 - 1.7e-72 243.8 0.1 1.4e-67 227.6 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAJ02193.1 - 1.5e-05 25.7 1.1 8.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 OAJ02193.1 - 0.00035 20.4 0.0 0.0018 18.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 OAJ02193.1 - 0.00064 19.6 0.1 0.00064 19.6 0.1 1.9 2 1 0 2 2 1 1 AAA domain SRP54 PF00448.17 OAJ02193.1 - 0.0011 18.4 0.9 0.0071 15.8 0.1 2.4 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 OAJ02193.1 - 0.0016 18.7 0.0 0.0052 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ02193.1 - 0.0027 17.2 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 OAJ02193.1 - 0.0039 17.3 0.1 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 OAJ02193.1 - 0.007 15.7 1.0 0.21 10.9 0.7 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 OAJ02193.1 - 0.0075 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 OAJ02193.1 - 0.0081 15.5 1.4 0.033 13.5 1.0 2.1 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAJ02193.1 - 0.01 15.3 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 OAJ02193.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF1633 PF07794.6 OAJ02193.1 - 0.019 12.9 3.9 0.027 12.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) ArgK PF03308.11 OAJ02193.1 - 0.021 13.5 0.9 0.86 8.3 0.1 2.4 2 1 0 2 2 2 0 ArgK protein Miro PF08477.8 OAJ02193.1 - 0.027 14.9 0.0 4.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein MobB PF03205.9 OAJ02193.1 - 0.034 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ02193.1 - 0.04 13.9 0.1 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 OAJ02193.1 - 0.05 13.5 0.8 0.086 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain CobU PF02283.11 OAJ02193.1 - 0.059 12.7 0.5 0.14 11.5 0.3 1.7 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_29 PF13555.1 OAJ02193.1 - 0.065 12.7 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 OAJ02193.1 - 0.085 12.2 0.1 15 4.9 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 OAJ02193.1 - 0.089 12.3 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ02193.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 OAJ02193.1 - 0.22 11.3 2.3 0.49 10.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Thymidylate_kin PF02223.12 OAJ02193.1 - 0.28 10.5 1.0 15 4.8 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase VWA_2 PF13519.1 OAJ02194.1 - 3.3e-13 50.0 0.1 1.3e-12 48.1 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 OAJ02194.1 - 1e-06 28.6 0.0 2.1e-05 24.3 0.0 2.4 2 1 0 3 3 3 1 von Willebrand factor type A domain Med25_VWA PF11265.3 OAJ02194.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.13 OAJ02194.1 - 0.16 10.8 0.0 1.3 7.7 0.0 2.0 1 1 0 1 1 1 0 Integrin, beta chain Mit_KHE1 PF10173.4 OAJ02195.1 - 1.6e-51 174.8 0.2 2.4e-51 174.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MSA-2c PF12238.3 OAJ02195.1 - 5.8 6.5 7.6 1 8.9 2.3 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c NADH_B2 PF14813.1 OAJ02196.1 - 0.00033 20.2 0.4 0.00041 19.9 0.3 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Ribosomal_S16 PF00886.14 OAJ02197.1 - 4.7e-24 83.8 4.0 1.6e-23 82.1 2.8 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 OAJ02198.1 - 3.9e-35 119.3 0.0 5e-14 51.6 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ02198.1 - 1.2e-33 114.8 0.0 5.9e-11 42.1 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02198.1 - 2.4e-14 52.8 0.0 2.2e-06 27.3 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ02198.1 - 4.9e-06 26.2 0.0 0.025 14.3 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 OAJ02198.1 - 0.0076 15.9 0.0 0.035 13.8 0.0 2.2 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 OAJ02198.1 - 0.11 12.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain NADHdh_A3 PF14987.1 OAJ02199.1 - 0.066 13.1 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Thiolase_N PF00108.18 OAJ02200.1 - 3.9e-70 235.8 0.1 5.5e-70 235.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ02200.1 - 1.5e-40 137.4 0.4 2.9e-40 136.4 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 OAJ02200.1 - 0.00013 21.5 0.0 0.0076 15.8 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 OAJ02200.1 - 0.024 14.1 2.3 0.13 11.6 0.9 2.6 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 OAJ02200.1 - 0.068 13.1 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF4504 PF14953.1 OAJ02201.1 - 7.4e-12 45.1 0.1 1.9e-09 37.2 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) FAD_binding_2 PF00890.19 OAJ02202.1 - 2.3e-82 277.1 0.0 2.7e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ02202.1 - 1.5e-07 31.2 0.1 5.4e-07 29.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ02202.1 - 6.1e-06 26.2 0.0 0.0025 17.6 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ02202.1 - 1e-05 24.6 0.6 6.6e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ02202.1 - 2.5e-05 24.5 0.3 0.0016 18.8 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ02202.1 - 0.00053 18.5 0.7 0.003 16.0 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 OAJ02202.1 - 0.0013 17.8 0.2 0.0044 16.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 OAJ02202.1 - 0.0033 16.5 0.1 0.0088 15.1 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAJ02202.1 - 0.0047 15.9 0.5 0.008 15.1 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 OAJ02202.1 - 0.032 13.1 2.3 0.035 12.9 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 OAJ02202.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 OAJ02202.1 - 0.13 11.8 2.5 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S5 PF00333.15 OAJ02203.1 - 9.5e-15 54.1 2.2 1.7e-14 53.2 1.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ02203.1 - 3e-14 52.0 0.0 9.7e-14 50.4 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Period_C PF12114.3 OAJ02203.1 - 0.19 11.3 15.4 0.3 10.6 10.7 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF566 PF04484.7 OAJ02203.1 - 0.22 11.0 18.8 0.35 10.3 13.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pex14_N PF04695.8 OAJ02203.1 - 0.32 11.0 7.6 0.59 10.1 5.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region COX6B PF02297.12 OAJ02204.1 - 1.9e-23 82.2 0.3 2.4e-23 81.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Peptidase_C70 PF12385.3 OAJ02204.1 - 0.011 15.5 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Glyco_hydro_9 PF00759.14 OAJ02205.1 - 8.7e-85 285.2 9.5 3e-50 171.4 2.3 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 Pkinase PF00069.20 OAJ02207.1 - 5.7e-58 196.1 0.0 2.4e-57 194.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02207.1 - 1.9e-25 89.4 0.0 4.1e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02207.1 - 6.5e-08 31.8 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ02207.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ02207.1 - 0.035 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Arginase PF00491.16 OAJ02208.1 - 2.6e-74 250.0 0.0 3e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family NAD_binding_10 PF13460.1 OAJ02209.1 - 2.9e-18 66.5 0.0 5.8e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ02209.1 - 3.3e-11 43.0 0.0 5.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 OAJ02209.1 - 6.7e-11 41.8 0.0 8.7e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 OAJ02209.1 - 1.3e-09 37.3 0.0 3e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 OAJ02209.1 - 1.5e-09 36.9 0.0 3.1e-09 35.9 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 OAJ02209.1 - 1.5e-06 27.3 0.3 0.0064 15.4 0.1 3.0 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.20 OAJ02209.1 - 0.0021 17.9 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 OAJ02209.1 - 0.0029 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 OAJ02209.1 - 0.013 14.3 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 OAJ02209.1 - 0.017 14.7 0.1 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 KR domain RVT_1 PF00078.22 OAJ02210.1 - 3.2e-23 82.2 0.0 5.5e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ02210.1 - 0.00049 19.6 0.0 0.00094 18.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SCP2 PF02036.12 OAJ02212.1 - 7.4e-09 35.8 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family GIDA PF01134.17 OAJ02214.1 - 0.26 10.1 0.4 7 5.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Rsa3 PF14615.1 OAJ02215.1 - 0.0006 19.0 0.0 0.0041 16.3 0.0 2.2 1 1 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.4 OAJ02215.1 - 6.9 6.0 67.6 2.5 7.5 20.6 3.1 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein MSP1_C PF07462.6 OAJ02215.1 - 8.8 4.5 9.7 12 4.1 6.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Zn_clus PF00172.13 OAJ02216.1 - 1.4e-06 28.0 11.5 3.1e-06 26.9 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RXT2_N PF08595.6 OAJ02216.1 - 0.12 12.2 2.9 0.22 11.2 2.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 OAJ02216.1 - 2 7.9 6.7 3.8 7.0 4.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 OAJ02216.1 - 5.6 4.8 11.2 9.8 4.0 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein FDF PF09532.5 OAJ02217.1 - 3.3e-08 33.9 0.0 3.3e-08 33.9 0.0 3.3 4 0 0 4 4 4 1 FDF domain LSM PF01423.17 OAJ02217.1 - 0.08 12.4 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 LSM domain SM-ATX PF14438.1 OAJ02217.1 - 0.14 12.0 0.0 0.61 10.0 0.0 2.1 1 0 0 1 1 1 0 Ataxin 2 SM domain hNIFK_binding PF12196.3 OAJ02217.1 - 0.72 9.2 4.4 7.4 6.0 0.2 3.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Ribosomal_L14 PF00238.14 OAJ02218.1 - 4.1e-34 116.9 0.0 4.7e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pro_isomerase PF00160.16 OAJ02219.1 - 1.2e-40 139.2 0.1 1.6e-40 138.8 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 OAJ02224.1 - 1.6e-20 72.5 5.2 2.8e-07 30.0 0.0 3.9 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ02224.1 - 4.9e-17 60.7 1.3 4e-05 23.0 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02224.1 - 1e-16 59.4 1.9 8.9e-05 22.1 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ02224.1 - 2.3e-14 53.6 0.8 5.3e-07 30.1 0.0 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02224.1 - 9.1e-12 44.5 4.9 0.052 14.1 0.0 5.7 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ02224.1 - 2.3e-11 43.8 2.4 5.4e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02224.1 - 6.9e-10 38.3 1.9 0.077 13.2 0.0 4.6 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ02224.1 - 4.7e-09 36.0 6.0 0.0011 18.8 0.0 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ02224.1 - 6.6e-09 34.9 3.7 0.084 12.6 0.2 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ02224.1 - 7.7e-09 35.4 0.6 0.00037 20.7 0.0 4.4 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ02224.1 - 5.5e-06 26.1 0.1 0.00098 18.9 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ02224.1 - 0.00036 20.1 1.8 0.37 10.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ02224.1 - 0.0015 18.6 0.1 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SPATA24 PF15175.1 OAJ02224.1 - 0.021 14.5 1.8 0.032 13.9 0.1 2.1 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 GCIP PF13324.1 OAJ02224.1 - 0.13 11.4 1.5 1.1 8.3 1.0 2.2 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting TPR_10 PF13374.1 OAJ02224.1 - 0.18 11.7 2.8 17 5.4 0.3 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 OAJ02225.1 - 1.5e-30 105.9 0.0 2.2e-29 102.1 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Helicase_C PF00271.26 OAJ02226.1 - 3.1e-16 58.9 0.0 1.6e-14 53.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ02226.1 - 9e-08 31.7 0.0 2.3e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ02226.1 - 0.06 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4269 PF14091.1 OAJ02226.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Zot PF05707.7 OAJ02226.1 - 0.17 11.3 0.1 0.5 9.8 0.1 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) PAXIP1_C PF15364.1 OAJ02230.1 - 0.048 13.5 1.4 1.9 8.3 0.2 2.2 1 1 1 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2721 PF11026.3 OAJ02231.1 - 0.13 11.8 0.4 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Velvet PF11754.3 OAJ02233.1 - 3.7e-25 88.7 0.1 2.3e-24 86.1 0.1 1.9 1 1 0 1 1 1 1 Velvet factor Exc PF07825.6 OAJ02233.1 - 0.063 13.0 0.2 5.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Excisionase-like protein RTC4 PF14474.1 OAJ02234.1 - 9.6e-08 32.0 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Flavoprotein PF02441.14 OAJ02235.1 - 7.3e-40 135.6 0.0 1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein AAA_assoc_C PF09821.4 OAJ02236.1 - 0.7 10.1 3.6 0.55 10.5 0.6 2.1 3 0 0 3 3 3 0 C-terminal AAA-associated domain Pkinase PF00069.20 OAJ02237.1 - 1.8e-40 138.7 0.0 2e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02237.1 - 5.3e-28 97.7 0.0 6.2e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02237.1 - 8.1e-07 28.2 0.0 1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Velvet PF11754.3 OAJ02238.1 - 1.4e-37 129.2 0.1 2.9e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Velvet factor UCH PF00443.24 OAJ02239.1 - 1e-33 116.6 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ02239.1 - 1.2e-10 41.3 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.15 OAJ02239.1 - 0.063 13.4 0.9 0.19 11.8 0.6 1.8 1 0 0 1 1 1 0 Putative cell wall binding repeat TSP9 PF11493.3 OAJ02239.1 - 0.075 13.5 0.5 7.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 Pkinase PF00069.20 OAJ02240.1 - 1.8e-69 233.8 0.0 2.3e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02240.1 - 1.9e-49 168.0 0.0 2.6e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02240.1 - 5.1e-06 25.6 0.0 3.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like HTH_Tnp_1 PF01527.15 OAJ02241.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Transposase Pkinase PF00069.20 OAJ02242.1 - 1.4e-48 165.3 0.0 1.7e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02242.1 - 2.8e-33 115.1 0.0 3.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02242.1 - 2.2e-06 26.8 0.0 4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 OAJ02245.1 - 2.7e-60 203.7 0.0 3.6e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02245.1 - 6.2e-31 107.4 0.0 8.5e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02245.1 - 0.0058 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ02245.1 - 0.027 14.1 0.7 0.65 9.6 0.0 2.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family MitMem_reg PF13012.1 OAJ02246.1 - 3.9e-33 113.9 0.6 1.1e-32 112.5 0.2 1.9 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAJ02246.1 - 3.3e-27 94.4 0.0 5.4e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3814 PF12769.2 OAJ02247.1 - 0.037 14.1 1.4 0.043 13.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) DUF4575 PF15143.1 OAJ02247.1 - 0.17 11.6 1.7 0.23 11.1 1.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4575) HIG_1_N PF04588.8 OAJ02247.1 - 0.28 10.9 0.1 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region RVT_2 PF07727.9 OAJ02248.1 - 1.9e-84 282.4 0.0 2.6e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02248.1 - 9.8e-29 99.9 0.0 1.8e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ02248.1 - 0.00012 21.4 0.0 0.00039 19.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain ClpS PF02617.12 OAJ02248.1 - 0.19 11.5 0.8 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS Atracotoxin PF05353.6 OAJ02249.1 - 0.024 14.4 0.1 0.024 14.4 0.1 2.8 3 1 0 3 3 3 0 Delta Atracotoxin DUF740 PF05340.7 OAJ02249.1 - 3.9 5.7 6.9 6 5.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Aldedh PF00171.17 OAJ02255.1 - 1.1e-32 113.0 0.7 2.1e-18 65.9 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DUF904 PF06005.7 OAJ02256.1 - 0.002 18.3 5.9 0.0043 17.3 4.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Chibby PF14645.1 OAJ02256.1 - 0.034 14.0 3.9 0.034 14.0 1.7 1.8 1 1 1 2 2 2 0 Chibby family bZIP_2 PF07716.10 OAJ02256.1 - 0.039 13.7 12.9 0.11 12.3 6.4 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 OAJ02256.1 - 0.17 12.2 2.3 0.41 10.9 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 OAJ02256.1 - 0.72 9.6 7.2 2.3 8.0 3.7 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper IncA PF04156.9 OAJ02256.1 - 0.96 9.0 6.7 0.064 12.8 0.8 1.7 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 OAJ02256.1 - 1.4 8.4 8.9 2.8 7.4 6.2 1.4 1 0 0 1 1 1 0 Septum formation initiator CDC27 PF09507.5 OAJ02257.1 - 0.2 10.8 4.4 0.3 10.2 3.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 OAJ02257.1 - 2.8 5.8 6.0 4 5.3 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldedh PF00171.17 OAJ02258.1 - 2.5e-179 596.4 0.8 2.9e-179 596.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ02258.1 - 0.0018 17.0 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) F-box PF00646.28 OAJ02259.1 - 0.052 13.2 0.5 1 9.0 0.0 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 OAJ02259.1 - 0.065 12.9 0.7 13 5.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like FMN_dh PF01070.13 OAJ02260.1 - 5.6e-120 400.4 0.0 7e-120 400.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 OAJ02260.1 - 2.4e-21 75.3 0.2 6e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 OAJ02260.1 - 2.8e-05 23.2 0.0 4.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ02260.1 - 0.0027 16.6 0.0 0.0059 15.5 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Vps5 PF09325.5 OAJ02260.1 - 0.081 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Vps5 C terminal like ADH_zinc_N_2 PF13602.1 OAJ02261.1 - 1.1e-16 61.8 0.1 3e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 OAJ02261.1 - 1.1e-14 54.1 0.2 2e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ02261.1 - 1.7e-07 30.9 0.0 8.8e-07 28.6 0.0 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 OAJ02261.1 - 0.016 14.7 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAGK_cat PF00781.19 OAJ02261.1 - 0.062 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain EF_assoc_1 PF08355.7 OAJ02262.1 - 0.069 12.4 0.1 0.48 9.7 0.1 2.0 2 0 0 2 2 2 0 EF hand associated Tox-PL-2 PF15643.1 OAJ02263.1 - 0.016 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Papain fold toxin 2 2-oxoacid_dh PF00198.18 OAJ02264.1 - 1.4e-79 266.6 1.0 2.3e-79 265.9 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ02264.1 - 3.1e-19 68.3 1.4 5.7e-19 67.5 1.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 OAJ02264.1 - 0.0047 17.2 0.1 4 7.8 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 OAJ02264.1 - 0.012 15.2 0.0 0.35 10.5 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.14 OAJ02264.1 - 0.027 14.1 0.5 0.065 12.9 0.3 1.6 1 1 0 1 1 1 0 Glycine cleavage H-protein DUF605 PF04652.11 OAJ02264.1 - 0.15 11.4 19.0 0.2 11.0 13.2 1.2 1 0 0 1 1 1 0 Vta1 like TFIIF_alpha PF05793.7 OAJ02264.1 - 0.18 10.1 30.8 0.26 9.6 21.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1770 PF08589.5 OAJ02266.1 - 4.3e-05 24.0 0.7 4.3e-05 24.0 0.5 2.5 2 1 1 3 3 3 1 Fungal protein of unknown function (DUF1770) SPT2 PF08243.6 OAJ02267.1 - 1.4e-17 64.0 6.0 1.4e-17 64.0 4.1 5.4 4 2 1 5 5 5 1 SPT2 chromatin protein SPT6_acidic PF14632.1 OAJ02267.1 - 0.014 15.5 17.2 0.014 15.5 12.0 5.3 4 1 0 4 4 4 0 Acidic N-terminal SPT6 AAA PF00004.24 OAJ02268.1 - 9.6e-14 51.7 0.0 1.3e-12 48.0 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ02268.1 - 1.4e-12 48.0 0.5 3.3e-11 43.5 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ02268.1 - 2e-08 34.4 0.0 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ02268.1 - 0.00019 21.1 1.8 0.00081 19.0 0.0 2.9 3 0 0 3 3 3 1 Part of AAA domain PIF1 PF05970.9 OAJ02268.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_11 PF13086.1 OAJ02268.1 - 0.018 14.6 0.7 0.04 13.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 OAJ02268.1 - 0.025 13.5 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 OAJ02268.1 - 0.033 13.8 0.0 0.34 10.5 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 OAJ02268.1 - 0.045 13.4 0.0 0.28 10.8 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 OAJ02268.1 - 0.055 12.9 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 OAJ02268.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Prominin PF05478.6 OAJ02268.1 - 0.18 9.3 0.1 0.29 8.6 0.0 1.2 1 0 0 1 1 1 0 Prominin Nop14 PF04147.7 OAJ02268.1 - 0.4 8.5 13.0 0.57 8.0 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 OAJ02268.1 - 0.87 8.5 22.4 0.095 11.7 12.2 1.7 2 0 0 2 2 2 0 BUD22 Adap_comp_sub PF00928.16 OAJ02269.1 - 3.2e-38 131.3 0.0 4.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RNase_PH PF01138.16 OAJ02270.1 - 1.5e-19 70.6 0.0 3.6e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Sad1_UNC PF07738.8 OAJ02271.1 - 1.1e-21 76.9 0.0 1.9e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Filament PF00038.16 OAJ02271.1 - 0.042 13.3 24.5 0.98 8.8 10.4 2.8 2 1 0 2 2 2 0 Intermediate filament protein Atg14 PF10186.4 OAJ02271.1 - 4.6 6.0 20.4 0.89 8.4 9.0 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADH_N PF08240.7 OAJ02272.1 - 4.2e-25 87.6 0.7 7.9e-25 86.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ02272.1 - 3.1e-21 75.2 0.1 4.8e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ02272.1 - 0.002 19.0 0.0 0.0048 17.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 OAJ02272.1 - 0.019 14.6 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 OAJ02272.1 - 0.024 13.1 0.2 0.032 12.7 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 OAJ02272.1 - 0.038 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 OAJ02272.1 - 0.041 14.4 0.0 0.096 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M16_C PF05193.16 OAJ02273.1 - 1.5e-39 135.5 0.0 3.7e-39 134.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAJ02273.1 - 1.7e-39 134.9 0.0 3e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PH_4 PF15404.1 OAJ02274.1 - 1.8e-29 102.5 0.0 4.7e-29 101.2 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ02274.1 - 0.0007 19.7 0.0 3 8.0 0.0 3.7 3 0 0 3 3 3 2 PH domain DUF2435 PF10363.4 OAJ02275.1 - 2.3e-24 85.1 0.8 3.3e-23 81.3 0.1 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 OAJ02275.1 - 0.0032 16.9 0.1 0.012 15.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT PF02985.17 OAJ02275.1 - 0.14 12.3 1.6 77 3.7 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat Endonuc-PvuII PF09225.5 OAJ02275.1 - 0.3 10.7 0.0 0.57 9.8 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease PvuII TPR_11 PF13414.1 OAJ02276.1 - 4.6e-11 42.2 10.7 2.4e-05 23.8 0.0 5.9 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 OAJ02276.1 - 6.7e-05 23.4 2.5 0.0039 17.8 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02276.1 - 0.00068 19.6 0.2 1.8 8.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ02276.1 - 0.014 14.9 2.0 2.2 8.0 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02276.1 - 0.034 14.7 11.5 0.067 13.8 0.1 6.5 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ02276.1 - 0.043 13.7 8.9 1.8 8.6 0.3 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc1 PF12859.2 OAJ02276.1 - 0.11 12.7 0.1 0.42 10.8 0.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 1 TPR_2 PF07719.12 OAJ02276.1 - 0.19 11.7 17.8 0.43 10.6 0.9 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ02276.1 - 0.59 10.1 13.5 10 6.1 0.0 5.8 5 2 2 7 7 6 0 Tetratricopeptide repeat Peptidase_S9_N PF02897.10 OAJ02277.1 - 2.7e-78 263.3 0.4 3.4e-78 263.0 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 OAJ02277.1 - 3.8e-48 163.5 0.5 1.9e-47 161.2 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Imm21 PF15569.1 OAJ02277.1 - 0.29 10.9 2.3 20 5.0 0.1 2.9 2 0 0 2 2 2 0 Immunity protein 21 Sin_N PF04801.8 OAJ02278.1 - 4.2e-15 55.5 1.1 1.4e-13 50.4 0.0 2.3 2 0 0 2 2 2 2 Sin-like protein conserved region ApbA_C PF08546.6 OAJ02279.1 - 2.4e-18 66.3 0.0 1.5e-09 37.8 0.0 2.6 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ02279.1 - 5.9e-17 61.5 0.8 2e-12 46.7 0.0 2.6 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 OAJ02279.1 - 0.1 13.0 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Gag_p15 PF08723.5 OAJ02279.1 - 0.12 12.3 0.1 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Gag protein p15 PX PF00787.19 OAJ02281.1 - 1.2e-18 66.9 0.0 2.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 PX domain RVT_1 PF00078.22 OAJ02282.1 - 2.2e-33 115.4 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pex14_N PF04695.8 OAJ02283.1 - 7.7 6.5 12.3 2.5 8.1 2.8 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.3 OAJ02283.1 - 8.8 5.4 13.8 15 4.6 9.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal dCMP_cyt_deam_1 PF00383.17 OAJ02285.1 - 4e-06 26.4 4.4 0.48 10.0 0.0 3.6 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region ORC6 PF05460.8 OAJ02286.1 - 0.38 9.7 2.4 0.44 9.5 1.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Transposase_21 PF02992.9 OAJ02292.1 - 4.8e-14 52.0 0.0 2.5e-13 49.6 0.0 2.1 3 0 0 3 3 3 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02292.1 - 1.4e-05 24.4 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PIN_4 PF13638.1 OAJ02293.1 - 7.5e-21 74.6 0.0 3.9e-20 72.2 0.0 2.2 1 1 0 1 1 1 1 PIN domain ADH_zinc_N PF00107.21 OAJ02296.1 - 1.6e-11 43.8 0.0 3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ02296.1 - 0.0031 17.2 0.0 0.02 14.6 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.2 OAJ02297.1 - 9.3e-23 80.3 2.6 2.4e-11 43.8 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ02297.1 - 2.1e-20 71.4 10.1 4.1e-11 42.1 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 OAJ02297.1 - 7.4e-16 58.1 2.1 5.7e-08 33.0 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ02297.1 - 1.1e-13 49.9 6.1 2.8e-05 23.9 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 OAJ02297.1 - 1.7e-12 47.1 3.0 1.5e-07 31.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) GIY-YIG PF01541.19 OAJ02297.1 - 4.4e-05 23.7 0.0 4.4e-05 23.7 0.0 3.1 3 1 0 3 3 3 1 GIY-YIG catalytic domain HrpA_pilin PF09589.5 OAJ02297.1 - 0.0034 17.8 0.0 0.27 11.6 0.0 3.4 2 2 0 2 2 2 1 HrpA pilus formation protein Gelsolin PF00626.17 OAJ02298.1 - 2.5e-37 126.4 0.1 1.2e-14 53.7 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat GCR1_C PF12550.3 OAJ02299.1 - 3.4e-06 26.8 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes rve PF00665.21 OAJ02301.1 - 2.4e-15 56.7 0.0 5.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 OAJ02301.1 - 5.7e-08 32.4 0.0 3e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ02301.1 - 1.6e-06 28.5 0.0 4.1e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 OAJ02301.1 - 3.6e-05 23.2 0.0 6.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 OAJ02301.1 - 6.5e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 OAJ02301.1 - 0.00023 20.7 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Rad60-SLD PF11976.3 OAJ02301.1 - 0.00087 18.9 0.0 4.6 7.0 0.0 3.7 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like RVP_2 PF08284.6 OAJ02301.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease GP41 PF00517.12 OAJ02302.1 - 0.075 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF4246 PF14033.1 OAJ02302.1 - 0.15 10.6 3.3 0.2 10.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF2076 PF09849.4 OAJ02302.1 - 0.16 12.0 8.6 0.015 15.3 2.9 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Snf7 PF03357.16 OAJ02303.1 - 3.7e-38 130.5 16.2 1.2e-37 128.9 11.5 1.6 2 0 0 2 2 2 1 Snf7 TPR_MLP1_2 PF07926.7 OAJ02303.1 - 0.0019 17.9 6.1 0.0029 17.3 4.2 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 OAJ02303.1 - 0.015 14.6 17.2 0.031 13.6 3.9 2.1 1 1 1 2 2 2 0 PspA/IM30 family Thioredoxin_7 PF13899.1 OAJ02303.1 - 0.095 12.7 0.3 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like YlqD PF11068.3 OAJ02303.1 - 0.38 10.7 12.0 1.7 8.6 8.3 1.9 1 1 0 1 1 1 0 YlqD protein OmpH PF03938.9 OAJ02303.1 - 7.5 6.4 13.3 36 4.2 9.2 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-BED PF02892.10 OAJ02304.1 - 0.0041 16.8 0.9 0.014 15.1 0.6 1.9 1 0 0 1 1 1 1 BED zinc finger DUF605 PF04652.11 OAJ02304.1 - 1 8.7 23.0 0.36 10.1 13.8 1.7 2 0 0 2 2 2 0 Vta1 like Macoilin PF09726.4 OAJ02304.1 - 1.1 7.4 13.0 1.2 7.3 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 OAJ02304.1 - 5.5 6.7 12.2 8 6.2 8.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 OAJ02305.1 - 2e-27 95.1 0.2 3.2e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ02305.1 - 5.7e-05 23.2 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ02305.1 - 0.0061 15.8 0.1 0.0061 15.8 0.1 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ02305.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cpn60_TCP1 PF00118.19 OAJ02307.1 - 5.1e-119 398.0 5.7 5.9e-119 397.8 4.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-C3HC4_3 PF13920.1 OAJ02308.1 - 6.9e-11 41.6 11.6 1.1e-10 40.9 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ02308.1 - 0.34 10.9 14.6 0.57 10.2 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4342 PF14242.1 OAJ02308.1 - 1 9.1 2.9 2.7 7.8 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) zf-RING_2 PF13639.1 OAJ02308.1 - 1.4 8.7 13.8 2.4 8.0 9.6 1.4 1 0 0 1 1 1 0 Ring finger domain SDA1 PF05285.7 OAJ02308.1 - 3.1 6.9 11.7 5.3 6.2 8.1 1.2 1 0 0 1 1 1 0 SDA1 CTK3 PF12243.3 OAJ02309.1 - 2e-27 95.5 0.1 3.3e-26 91.5 0.0 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 OAJ02309.1 - 4.1e-14 52.3 6.0 6e-11 42.2 0.1 3.3 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 C-terminus Pho88 PF10032.4 OAJ02310.1 - 1.8e-60 203.4 0.0 2e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) HTH_Tnp_Tc5 PF03221.11 OAJ02311.1 - 0.00012 21.8 0.0 0.00034 20.3 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.1 OAJ02311.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 OAJ02311.1 - 0.00048 19.6 0.0 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.2 OAJ02311.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 MarR family MarR PF01047.17 OAJ02311.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_28 PF13518.1 OAJ02311.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Crp_2 PF13545.1 OAJ02311.1 - 0.017 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_31 PF13560.1 OAJ02311.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.1 OAJ02311.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.8 OAJ02311.1 - 0.078 12.4 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.11 OAJ02311.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 OAJ02311.1 - 0.28 11.0 0.0 0.56 10.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix PGA2 PF07543.7 OAJ02311.1 - 2.5 7.9 9.9 3.9 7.2 6.9 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Pox_Ag35 PF03286.9 OAJ02311.1 - 5.4 6.4 10.3 12 5.3 7.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Snf7 PF03357.16 OAJ02312.1 - 3.6e-10 39.4 4.2 1.8e-09 37.2 3.1 1.8 2 0 0 2 2 2 1 Snf7 zf-CHCC PF10276.4 OAJ02313.1 - 1.5e-17 63.1 1.1 1.5e-17 63.1 0.8 1.6 2 0 0 2 2 2 1 Zinc-finger domain COX5B PF01215.14 OAJ02313.1 - 0.0042 16.7 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb DUF605 PF04652.11 OAJ02313.1 - 0.075 12.4 7.5 0.082 12.2 5.2 1.0 1 0 0 1 1 1 0 Vta1 like ADK PF00406.17 OAJ02314.1 - 3.3e-46 156.9 0.0 4e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 OAJ02314.1 - 1.5e-10 41.4 0.0 2.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 OAJ02314.1 - 3.9e-08 32.8 0.2 0.0029 17.0 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 OAJ02314.1 - 6.6e-06 26.9 0.0 9.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ02314.1 - 0.00043 20.1 0.0 0.0024 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 OAJ02314.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAJ02314.1 - 0.12 12.1 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Med21 PF11221.3 OAJ02315.1 - 3e-12 46.7 1.1 3.6e-12 46.4 0.8 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex IncA PF04156.9 OAJ02315.1 - 0.0016 18.0 4.3 0.0018 17.8 3.0 1.1 1 0 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 OAJ02315.1 - 0.0054 14.5 3.9 0.0064 14.2 2.7 1.0 1 0 0 1 1 1 1 Myosin tail LMP PF04778.7 OAJ02315.1 - 0.018 14.8 0.3 0.024 14.4 0.2 1.1 1 0 0 1 1 1 0 LMP repeated region Macoilin PF09726.4 OAJ02315.1 - 0.055 11.7 1.3 0.058 11.6 0.9 1.0 1 0 0 1 1 1 0 Transmembrane protein FUSC PF04632.7 OAJ02315.1 - 1.3 7.3 6.6 1.3 7.3 4.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HbrB PF08539.6 OAJ02316.1 - 3.4e-19 69.2 0.0 4.2e-08 33.1 0.0 3.1 2 1 0 2 2 2 2 HbrB-like Tannase PF07519.6 OAJ02321.1 - 2.6e-64 217.7 0.0 5.5e-63 213.3 0.0 2.1 1 1 0 1 1 1 1 Tannase and feruloyl esterase Ras PF00071.17 OAJ02322.1 - 4.4e-36 123.7 0.0 5e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ02322.1 - 5.6e-11 42.9 0.0 8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 OAJ02322.1 - 0.003 17.0 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 OAJ02322.1 - 0.018 14.2 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family Man-6-P_recep PF02157.10 OAJ02322.1 - 0.055 12.4 0.4 0.12 11.3 0.3 1.6 1 1 0 1 1 1 0 Mannose-6-phosphate receptor FeoB_N PF02421.13 OAJ02322.1 - 0.069 12.4 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Baculo_PEP_C PF04513.7 OAJ02323.1 - 0.74 9.6 4.0 6.4 6.5 0.1 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNARE_assoc PF09335.6 OAJ02324.1 - 1.4e-13 51.1 5.4 1.4e-13 51.1 3.7 3.0 3 1 0 3 3 3 2 SNARE associated Golgi protein Arrestin_N PF00339.24 OAJ02325.1 - 0.0099 15.7 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L13 PF00572.13 OAJ02326.1 - 2.1e-49 166.8 0.6 2.4e-49 166.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SH3_9 PF14604.1 OAJ02327.1 - 1.3e-22 79.1 1.2 5e-14 51.6 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 OAJ02327.1 - 8.1e-21 73.1 0.0 7e-10 38.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 OAJ02327.1 - 1.3e-15 56.5 0.2 4.5e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 OAJ02327.1 - 3.2e-13 49.6 2.6 1.4e-12 47.6 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 OAJ02327.1 - 1.5e-11 43.8 4.7 3e-11 42.8 3.3 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 OAJ02327.1 - 0.00015 21.9 1.1 0.0003 20.8 0.2 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain LPP20 PF02169.11 OAJ02327.1 - 5 7.2 6.9 0.4 10.7 0.4 2.5 3 0 0 3 3 3 0 LPP20 lipoprotein Adeno_E3_CR2 PF02439.10 OAJ02328.1 - 0.013 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mob1_phocein PF03637.12 OAJ02329.1 - 1.6e-72 242.8 0.1 1.9e-72 242.6 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Tannase PF07519.6 OAJ02330.1 - 1.2e-66 225.4 0.0 1.1e-64 218.9 0.0 2.2 1 1 0 1 1 1 1 Tannase and feruloyl esterase AMP-binding PF00501.23 OAJ02331.1 - 1.5e-77 260.7 0.0 1.1e-76 257.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ02331.1 - 2.2e-08 34.9 0.0 1e-06 29.5 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 OAJ02332.1 - 2.1e-26 92.8 1.4 3.6e-26 92.0 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ02332.1 - 2.1e-11 43.8 0.9 7.2e-11 42.0 0.6 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ02332.1 - 2e-08 34.3 0.0 2.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAJ02332.1 - 0.013 14.9 0.2 0.051 12.9 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ02332.1 - 0.023 14.7 0.5 0.047 13.7 0.4 1.5 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAJ02332.1 - 0.031 13.1 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PA PF02225.17 OAJ02332.1 - 0.035 13.8 1.6 0.41 10.3 1.2 2.7 2 1 0 2 2 2 0 PA domain Methyltransf_25 PF13649.1 OAJ02332.1 - 0.044 14.1 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ02332.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pyridoxal_deC PF00282.14 OAJ02333.1 - 4.4e-72 242.5 0.0 5.9e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ02333.1 - 0.0011 18.1 0.0 0.0027 16.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase RRM_6 PF14259.1 OAJ02334.1 - 5e-37 125.7 0.3 5.8e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ02334.1 - 1.6e-28 98.1 0.7 1.9e-08 33.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02334.1 - 4.6e-20 71.2 0.1 3.8e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ02334.1 - 0.0014 18.4 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif DIL PF01843.14 OAJ02335.1 - 4e-19 68.4 0.5 9.1e-19 67.2 0.3 1.6 1 1 0 1 1 1 1 DIL domain Ank_2 PF12796.2 OAJ02335.1 - 2.7e-16 59.6 0.0 2.8e-15 56.4 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ02335.1 - 7e-14 50.8 0.0 7.9e-07 28.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ02335.1 - 8.4e-13 48.4 0.0 2e-09 37.7 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ02335.1 - 2.9e-11 42.4 0.1 6.2e-05 22.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 OAJ02335.1 - 3.9e-11 42.8 0.2 4.6e-07 29.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Lge1 PF11488.3 OAJ02335.1 - 0.013 15.6 1.2 0.04 14.1 0.8 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 UPF0061 PF02696.9 OAJ02336.1 - 4.4e-80 269.3 0.0 1.1e-79 268.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family ABC_tran PF00005.22 OAJ02337.1 - 1.9e-51 173.9 0.0 1.8e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ02337.1 - 2.7e-45 154.9 15.7 1.9e-20 73.4 0.0 4.5 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 OAJ02337.1 - 3.7e-12 45.9 0.3 7.4e-05 22.0 0.0 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ02337.1 - 6.8e-07 28.7 0.3 0.014 14.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ02337.1 - 9.2e-07 28.4 0.0 0.037 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAJ02337.1 - 4.3e-06 25.9 0.0 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 OAJ02337.1 - 6.5e-06 25.3 0.2 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.1 OAJ02337.1 - 1.1e-05 25.6 0.1 1 9.2 0.0 4.1 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 OAJ02337.1 - 3e-05 24.5 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 OAJ02337.1 - 8.3e-05 22.5 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ02337.1 - 9.1e-05 22.3 0.9 0.25 11.1 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.1 OAJ02337.1 - 9.4e-05 22.8 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ02337.1 - 0.00011 21.7 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ02337.1 - 0.00043 20.1 0.4 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 OAJ02337.1 - 0.00045 20.3 0.2 2 8.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 OAJ02337.1 - 0.00046 20.9 0.0 0.048 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ02337.1 - 0.0011 17.9 0.2 0.9 8.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_10 PF12846.2 OAJ02337.1 - 0.0013 18.2 0.1 1.6 8.0 0.0 3.2 4 0 0 4 4 4 1 AAA-like domain T2SE PF00437.15 OAJ02337.1 - 0.0018 17.2 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ02337.1 - 0.0022 18.0 4.6 0.68 9.8 0.1 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.1 OAJ02337.1 - 0.0045 16.8 0.1 3.1 7.6 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.1 OAJ02337.1 - 0.013 15.8 0.5 1.4 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain BCA_ABC_TP_C PF12399.3 OAJ02337.1 - 0.041 13.5 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter IstB_IS21 PF01695.12 OAJ02337.1 - 0.051 12.9 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ02337.1 - 0.057 13.5 0.1 8 6.6 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 OAJ02337.1 - 0.068 12.8 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 OAJ02337.1 - 0.1 11.1 0.3 2.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AIG1 PF04548.11 OAJ02337.1 - 0.65 9.0 0.8 8 5.5 0.0 2.4 2 0 0 2 2 2 0 AIG1 family cobW PF02492.14 OAJ02337.1 - 0.71 9.2 1.7 6.2 6.2 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytochrom_B561 PF03188.11 OAJ02338.1 - 3.2e-09 36.7 10.5 3.2e-09 36.7 7.2 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ02338.1 - 1.6e-05 24.7 0.1 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAJ02338.1 - 0.24 10.9 8.2 0.33 10.5 4.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 OAJ02339.1 - 3.8e-09 36.4 8.2 8e-09 35.4 5.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 OAJ02339.1 - 1.5e-05 24.9 0.2 2.4e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 OAJ02339.1 - 0.00047 19.6 3.6 0.0024 17.4 2.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) Nucleoplasmin PF03066.10 OAJ02340.1 - 0.17 11.3 4.5 0.31 10.5 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 OAJ02340.1 - 0.47 10.2 3.7 1 9.1 2.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 OAJ02340.1 - 2 6.2 8.9 3.6 5.3 6.2 1.3 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 OAJ02340.1 - 6.8 7.0 13.8 1.1 9.5 6.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Toxin_29 PF08116.6 OAJ02342.1 - 0.26 11.1 0.0 0.26 11.1 0.0 5.8 5 1 1 6 6 6 0 PhTx neurotoxin family PI3_PI4_kinase PF00454.22 OAJ02346.1 - 3e-32 111.9 0.0 1.8e-31 109.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 OAJ02346.1 - 1.2e-26 93.0 0.4 1.5e-25 89.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ipi1_N PF12333.3 OAJ02346.1 - 0.011 15.6 0.0 0.099 12.6 0.0 2.7 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Utp14 PF04615.8 OAJ02347.1 - 4.7e-153 511.0 47.0 4.7e-153 511.0 32.6 2.5 1 1 1 2 2 2 1 Utp14 protein Abhydrolase_3 PF07859.8 OAJ02348.1 - 6.8e-17 61.7 0.0 9.5e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ02348.1 - 1.1e-10 40.7 0.0 0.00026 19.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ02348.1 - 0.00075 19.2 0.0 0.0013 18.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family 60KD_IMP PF02096.15 OAJ02348.1 - 0.052 13.1 0.1 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Peptidase_M48 PF01435.13 OAJ02350.1 - 0.054 13.0 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 DUF1793 PF08760.6 OAJ02351.1 - 1.7e-65 220.0 0.4 3e-65 219.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) PI3_PI4_kinase PF00454.22 OAJ02351.1 - 1.8e-06 27.5 0.0 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UPF0113 PF03657.8 OAJ02352.1 - 7.7e-12 45.1 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) HMGL-like PF00682.14 OAJ02353.1 - 1.1e-71 241.2 0.2 2.2e-71 240.3 0.2 1.5 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.1 OAJ02353.1 - 0.11 12.6 0.4 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 FliG N-terminal domain DUF3439 PF11921.3 OAJ02354.1 - 0.0013 18.4 2.8 0.0019 17.9 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Peptidase_M56 PF05569.6 OAJ02354.1 - 0.0063 15.5 0.3 0.0076 15.2 0.2 1.1 1 0 0 1 1 1 1 BlaR1 peptidase M56 Potyvirid-P3 PF13608.1 OAJ02354.1 - 0.01 15.0 1.6 0.011 14.8 1.1 1.0 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein Pap_E4 PF02711.9 OAJ02354.1 - 0.038 14.7 7.2 0.038 14.7 5.0 1.9 2 0 0 2 2 2 0 E4 protein RAP1 PF07218.6 OAJ02354.1 - 0.057 11.5 1.5 0.064 11.3 1.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SSP160 PF06933.6 OAJ02354.1 - 0.1 10.5 6.7 0.13 10.2 4.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4381 PF14316.1 OAJ02354.1 - 0.12 12.4 0.5 0.26 11.4 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF912 PF06024.7 OAJ02354.1 - 0.21 11.6 1.6 0.32 11.0 0.3 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AIF_C PF14721.1 OAJ02354.1 - 0.37 11.0 4.4 0.18 12.0 0.1 1.9 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF966 PF06136.8 OAJ02354.1 - 0.49 9.7 7.9 0.65 9.3 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Folate_carrier PF01770.13 OAJ02354.1 - 1 7.8 4.8 0.46 8.9 0.8 1.8 1 1 1 2 2 2 0 Reduced folate carrier DUF1068 PF06364.7 OAJ02354.1 - 2.5 7.6 7.6 3.8 7.0 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1068) SelP_N PF04592.9 OAJ02354.1 - 6.3 6.0 9.6 14 4.9 6.7 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Trs65 PF12735.2 OAJ02354.1 - 7 5.8 10.2 9 5.5 7.0 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 SR-25 PF10500.4 OAJ02355.1 - 0.0008 18.9 7.1 0.002 17.6 4.9 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IQ PF00612.22 OAJ02355.1 - 0.0013 18.1 0.5 0.0031 17.0 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRI PF15325.1 OAJ02355.1 - 0.61 11.0 7.5 0.7 10.8 3.9 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF755 PF05501.6 OAJ02355.1 - 1.6 8.7 9.2 3.9 7.5 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Rax2 PF12768.2 OAJ02356.1 - 3e-82 276.0 1.2 8.3e-60 202.3 0.0 5.4 4 2 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 OAJ02356.1 - 1.2e-14 53.4 0.0 2.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ02356.1 - 2.8e-11 42.8 0.0 6.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ02356.1 - 2e-07 30.4 0.0 4.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TFIIF_alpha PF05793.7 OAJ02356.1 - 2.7 6.2 1.3 3.9 5.7 0.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CcoS PF03597.10 OAJ02356.1 - 5.6 6.5 5.6 13 5.3 3.9 1.6 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SET PF00856.23 OAJ02357.1 - 8e-24 84.7 3.1 2.3e-23 83.2 0.0 2.7 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ02357.1 - 1.3e-14 54.2 7.1 1.3e-14 54.2 4.9 1.9 2 0 0 2 2 2 1 Pre-SET motif DnaJ_CXXCXGXG PF00684.14 OAJ02358.1 - 2e-05 24.5 2.9 0.021 14.8 0.1 2.4 2 0 0 2 2 2 2 DnaJ central domain PADR1 PF08063.7 OAJ02358.1 - 0.039 13.3 7.4 0.055 12.8 0.6 3.0 3 0 0 3 3 3 0 PADR1 (NUC008) domain DAO PF01266.19 OAJ02359.1 - 1.8e-20 73.1 0.7 3.9e-20 72.0 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ02359.1 - 7.5e-06 26.2 0.1 0.031 14.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ02359.1 - 0.00054 19.9 0.4 0.0017 18.3 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ02359.1 - 0.0084 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 OAJ02359.1 - 0.052 12.1 0.8 0.98 7.9 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 OAJ02359.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.10 OAJ02359.1 - 0.28 9.3 0.0 6.9 4.7 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD-oxidase_C PF02913.14 OAJ02360.1 - 2.7e-51 174.2 0.0 5.1e-51 173.3 0.0 1.4 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ02360.1 - 5e-26 90.8 0.0 1.6e-25 89.2 0.0 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ02360.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like PQ-loop PF04193.9 OAJ02361.1 - 1.8e-36 123.4 10.6 1.9e-18 65.7 1.3 2.5 2 0 0 2 2 2 2 PQ loop repeat Mg_trans_NIPA PF05653.9 OAJ02361.1 - 0.014 14.4 4.6 0.016 14.2 2.5 1.6 1 1 0 1 1 1 0 Magnesium transporter NIPA Form-deh_trans PF09163.6 OAJ02361.1 - 0.098 12.1 0.0 0.098 12.1 0.0 2.2 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane UPF0061 PF02696.9 OAJ02361.1 - 0.12 10.6 0.6 0.19 9.9 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Frag1 PF10277.4 OAJ02361.1 - 0.23 10.9 11.8 1.1 8.6 8.2 2.0 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF3522 PF12036.3 OAJ02361.1 - 0.88 9.3 6.3 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3522) Erf4 PF10256.4 OAJ02362.1 - 5.5e-32 110.1 0.0 6.5e-32 109.8 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb5_C PF01191.14 OAJ02363.1 - 2e-34 116.9 0.1 3.9e-34 116.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 OAJ02363.1 - 1.5e-29 102.2 0.9 2.9e-29 101.3 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 OAJ02363.1 - 2.6e-05 24.0 0.2 6.1e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Restriction endonuclease Ebola_NP PF05505.7 OAJ02363.1 - 0.11 10.5 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Adap_comp_sub PF00928.16 OAJ02365.1 - 2.1e-89 299.1 0.1 3e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ02365.1 - 1.1e-05 25.2 0.6 2.1e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 OAJ02365.1 - 0.03 14.1 0.2 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) tRNA_int_endo PF01974.12 OAJ02366.1 - 1.1e-39 134.1 0.3 5.1e-19 67.8 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 OAJ02366.1 - 0.0013 18.2 0.5 0.0031 17.0 0.3 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain MitMem_reg PF13012.1 OAJ02367.1 - 4.2e-20 71.9 0.0 6.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 OAJ02367.1 - 3.1e-14 52.7 0.0 7.3e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank_5 PF13857.1 OAJ02368.1 - 8e-12 44.9 2.3 0.0039 17.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ02368.1 - 3.1e-10 40.2 0.1 0.0022 18.2 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAJ02368.1 - 8.7e-10 37.8 0.4 0.012 15.8 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ02368.1 - 4.9e-07 30.1 1.3 0.11 13.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ02368.1 - 4e-06 26.3 10.1 0.0062 16.2 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 OAJ02368.1 - 0.0007 19.1 0.0 0.002 17.6 0.0 1.7 1 1 0 1 1 1 1 KilA-N domain MitMem_reg PF13012.1 OAJ02368.1 - 0.15 12.1 1.2 0.29 11.2 0.8 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function IncA PF04156.9 OAJ02368.1 - 0.91 9.0 5.8 0.38 10.3 1.9 1.8 2 0 0 2 2 2 0 IncA protein Aldo_ket_red PF00248.16 OAJ02370.1 - 3.5e-08 32.6 0.0 4e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 OAJ02371.1 - 8.8e-16 57.5 0.0 9.9e-16 57.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L19e PF01280.15 OAJ02375.1 - 1.4e-59 200.1 12.6 1.4e-59 200.1 8.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 OAJ02375.1 - 0.0032 16.8 0.2 0.01 15.2 0.1 1.8 1 0 0 1 1 1 1 S4 domain AA_permease_2 PF13520.1 OAJ02376.1 - 1.4e-82 277.5 40.2 1.7e-82 277.2 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ02376.1 - 6.6e-21 74.2 34.8 1.6e-20 72.9 24.1 1.5 1 1 0 1 1 1 1 Amino acid permease Cellulase PF00150.13 OAJ02377.1 - 3.4e-11 42.8 0.5 5.2e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.13 OAJ02379.1 - 2e-08 34.0 27.2 5.8e-06 26.1 5.9 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 OAJ02379.1 - 1.4 8.4 16.6 2.5 7.5 1.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ02379.1 - 3.3 7.2 14.4 6.6 6.2 2.1 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ02379.1 - 8 6.7 19.8 8 6.7 5.1 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ02379.1 - 9.1 6.6 15.2 13 6.2 4.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribonuc_L-PSP PF01042.16 OAJ02380.1 - 4e-40 136.3 0.1 5.3e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_S27e PF01667.12 OAJ02381.1 - 2.1e-29 100.8 2.4 2.1e-29 100.8 1.7 1.5 2 0 0 2 2 2 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ02381.1 - 0.056 12.9 1.4 0.097 12.1 1.0 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF3133 PF11331.3 OAJ02381.1 - 0.22 11.1 5.6 0.71 9.4 2.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Ribosomal_S27e PF01667.12 OAJ02382.1 - 1.4e-29 101.3 2.4 2.1e-29 100.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.8 OAJ02382.1 - 0.029 13.8 0.5 0.052 13.0 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF3133 PF11331.3 OAJ02382.1 - 0.18 11.4 5.2 0.55 9.8 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) SUR7 PF06687.7 OAJ02383.1 - 8.1e-26 90.9 1.6 9.9e-26 90.6 1.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tetraspannin PF00335.15 OAJ02383.1 - 0.0028 16.9 6.4 0.0028 16.9 4.4 2.7 2 1 1 3 3 3 1 Tetraspanin family Fig1 PF12351.3 OAJ02383.1 - 0.01 15.7 1.1 0.013 15.3 0.1 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Lig_chan PF00060.21 OAJ02383.1 - 0.14 11.8 0.4 0.29 10.8 0.1 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF2207 PF09972.4 OAJ02383.1 - 0.16 10.5 1.4 0.15 10.5 0.3 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Peptidase_C48 PF02902.14 OAJ02384.1 - 5.1e-28 98.1 0.4 2.4e-27 95.9 0.1 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain AT_hook PF02178.14 OAJ02385.1 - 0.23 11.2 10.4 5.1 7.1 0.1 3.2 2 0 0 2 2 2 0 AT hook motif CTDII PF01556.13 OAJ02388.1 - 4.6e-30 103.3 0.2 9.2e-22 76.7 0.0 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 OAJ02388.1 - 1.8e-21 75.6 3.9 2.9e-21 74.9 2.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ02388.1 - 2.9e-09 36.8 18.3 6.4e-09 35.7 12.7 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF912 PF06024.7 OAJ02388.1 - 0.0022 18.0 0.7 0.0062 16.5 0.5 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) MCLC PF05934.6 OAJ02388.1 - 0.084 11.1 3.9 0.17 10.1 2.7 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Acetyltransf_1 PF00583.19 OAJ02389.1 - 1.3e-12 47.5 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ02389.1 - 8.3e-05 22.6 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ02389.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 OAJ02389.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MIS13 PF08202.6 OAJ02389.1 - 0.038 13.0 0.6 0.081 11.9 0.0 1.7 2 0 0 2 2 2 0 Mis12-Mtw1 protein family adh_short PF00106.20 OAJ02390.1 - 6.8e-17 61.8 0.1 6.8e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 OAJ02390.1 - 1.3e-08 34.7 0.1 2.1e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ02390.1 - 4.3e-06 26.6 0.0 8.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Clathrin PF00637.15 OAJ02391.1 - 1.2e-179 589.0 32.1 4.7e-33 113.7 0.1 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 OAJ02391.1 - 1.1e-30 105.2 0.1 4.7e-30 103.2 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 OAJ02391.1 - 2.1e-29 99.7 7.9 0.00032 20.8 0.0 7.3 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin-link PF09268.5 OAJ02391.1 - 9.5e-10 37.3 0.3 2.7e-09 35.8 0.2 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 OAJ02391.1 - 4.1e-05 22.5 11.2 0.23 10.2 0.1 4.8 5 0 0 5 5 5 3 Coatomer WD associated region TPR_7 PF13176.1 OAJ02391.1 - 0.0066 16.1 8.8 33 4.5 0.0 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02391.1 - 0.078 12.9 16.3 6.3 6.9 0.1 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ02391.1 - 0.16 11.8 7.6 41 4.2 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02391.1 - 0.17 12.1 3.1 32 5.0 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ02391.1 - 0.23 11.1 12.7 5.2 6.7 0.1 6.0 5 1 0 5 5 5 0 TPR repeat TPR_12 PF13424.1 OAJ02391.1 - 0.81 9.6 17.1 28 4.7 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ02391.1 - 1.9 8.2 16.4 9.7 5.9 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02391.1 - 8.7 7.2 24.4 53 4.8 0.1 10.1 11 1 1 12 12 11 0 Tetratricopeptide repeat AAA PF00004.24 OAJ02392.1 - 3.7e-43 146.8 0.0 6.1e-43 146.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ02392.1 - 4e-07 29.8 0.1 5.6e-06 26.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ02392.1 - 5.1e-07 29.8 0.0 2.9e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 OAJ02392.1 - 9.7e-07 28.8 0.0 7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ02392.1 - 2.6e-06 27.5 0.1 0.0013 18.9 0.0 2.8 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 OAJ02392.1 - 1.1e-05 24.5 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 OAJ02392.1 - 6.8e-05 22.5 0.1 0.00021 20.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ02392.1 - 0.00023 21.9 0.4 0.0013 19.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ02392.1 - 0.00076 18.4 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 OAJ02392.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ02392.1 - 0.0032 16.6 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 OAJ02392.1 - 0.0034 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ02392.1 - 0.0036 16.0 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 OAJ02392.1 - 0.0037 17.5 0.1 0.016 15.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 OAJ02392.1 - 0.0041 17.0 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 OAJ02392.1 - 0.006 16.0 0.0 0.033 13.6 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 OAJ02392.1 - 0.0072 16.2 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 OAJ02392.1 - 0.0077 15.6 0.2 0.036 13.4 0.1 2.0 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 OAJ02392.1 - 0.0092 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 OAJ02392.1 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ02392.1 - 0.011 15.2 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ02392.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 OAJ02392.1 - 0.014 15.1 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4200 PF13863.1 OAJ02392.1 - 0.015 15.2 0.2 0.015 15.2 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) PhoH PF02562.11 OAJ02392.1 - 0.016 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 OAJ02392.1 - 0.039 13.0 0.1 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.12 OAJ02392.1 - 0.052 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 OAJ02392.1 - 0.052 13.1 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 OAJ02392.1 - 0.053 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 OAJ02392.1 - 0.065 12.9 0.0 0.34 10.5 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 OAJ02392.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.8 1 1 0 1 1 1 0 NACHT domain CPT PF07931.7 OAJ02392.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Tmemb_cc2 PF10267.4 OAJ02392.1 - 0.13 10.8 0.5 0.3 9.6 0.1 1.8 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein AAA_23 PF13476.1 OAJ02392.1 - 0.69 10.2 3.9 4.9 7.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain Tom22 PF04281.8 OAJ02399.1 - 1.7e-35 121.5 0.0 4.6e-33 113.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.1 OAJ02399.1 - 0.084 12.7 3.4 0.13 12.0 2.4 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Nucleoplasmin PF03066.10 OAJ02399.1 - 0.56 9.7 3.7 0.76 9.2 2.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 OAJ02399.1 - 6 6.0 5.2 7.8 5.6 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein SET PF00856.23 OAJ02400.1 - 4.2e-18 66.1 0.1 4.2e-18 66.1 0.0 3.6 2 2 0 2 2 2 1 SET domain PHD PF00628.24 OAJ02401.1 - 1.4e-05 24.6 19.2 2.3e-05 23.9 13.3 1.4 1 0 0 1 1 1 1 PHD-finger DUF3918 PF13056.1 OAJ02401.1 - 0.051 12.8 2.2 0.53 9.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ribosomal_L6e PF01159.14 OAJ02402.1 - 9.5e-34 115.9 0.3 1.8e-33 115.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 OAJ02402.1 - 0.00061 19.6 0.8 0.00061 19.6 0.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain Hc1 PF07432.8 OAJ02402.1 - 5.6 7.1 20.9 3.3 7.9 6.7 2.2 2 0 0 2 2 2 0 Histone H1-like protein Hc1 ThiF PF00899.16 OAJ02403.1 - 1.5e-39 134.8 0.1 9.8e-39 132.2 0.0 1.9 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 OAJ02403.1 - 8e-25 86.2 1.3 1.7e-24 85.1 0.9 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 OAJ02403.1 - 1e-23 82.8 0.0 1.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 OAJ02403.1 - 2.3e-18 65.2 1.9 4.9e-18 64.2 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 OAJ02403.1 - 0.00083 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 OAJ02403.1 - 0.0059 16.1 0.4 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain DAO PF01266.19 OAJ02403.1 - 0.06 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ02403.1 - 0.076 12.4 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 OAJ02403.1 - 0.17 12.3 0.1 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.3 OAJ02403.1 - 0.26 11.2 2.3 0.5 10.2 1.6 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Mit_ribos_Mrp51 PF11709.3 OAJ02404.1 - 2.7 7.1 7.5 1 8.5 3.4 1.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein subunit Glyco_hydro_16 PF00722.16 OAJ02405.1 - 3.1e-08 33.1 0.1 5.6e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Solute_trans_a PF03619.11 OAJ02406.1 - 2.9e-32 112.0 1.9 3.3e-32 111.9 1.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 OAJ02406.1 - 0.041 13.7 4.1 0.047 13.5 2.0 1.7 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PrgI PF12666.2 OAJ02406.1 - 0.28 11.3 2.2 0.29 11.3 0.7 1.7 1 1 1 2 2 2 0 PrgI family protein Abhydrolase_3 PF07859.8 OAJ02407.1 - 9.3e-34 116.8 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ02407.1 - 8.1e-06 25.2 0.0 0.032 13.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ02407.1 - 9.5e-06 25.4 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 OAJ02407.1 - 0.00019 20.9 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 OAJ02407.1 - 0.00057 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.6 OAJ02407.1 - 0.003 17.2 0.0 0.0069 16.1 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 OAJ02407.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peroxidase_2 PF01328.12 OAJ02408.1 - 2.1e-15 56.2 0.7 5.6e-15 54.8 0.5 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 Solute_trans_a PF03619.11 OAJ02409.1 - 1.1e-32 113.5 8.5 1.4e-32 113.1 5.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF791 PF05631.9 OAJ02409.1 - 0.12 11.0 1.2 0.18 10.4 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) DUF3572 PF12096.3 OAJ02410.1 - 0.099 12.4 0.0 0.42 10.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3572) Peroxidase_2 PF01328.12 OAJ02411.1 - 1.1e-17 63.6 0.1 2.1e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 PTPA PF03095.10 OAJ02413.1 - 6.4e-52 176.5 0.0 8.7e-52 176.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAO PF01266.19 OAJ02413.1 - 8.5e-09 34.7 0.1 1.4e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 OAJ02413.1 - 0.00023 20.3 0.9 0.00023 20.3 0.6 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ02413.1 - 0.001 18.0 0.4 0.001 18.0 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ02413.1 - 0.022 14.6 0.1 0.022 14.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ02413.1 - 0.033 13.2 0.2 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 OAJ02413.1 - 0.053 11.9 0.3 0.074 11.5 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 OAJ02413.1 - 0.069 13.5 0.5 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ02413.1 - 0.073 13.1 0.4 0.073 13.1 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 OAJ02413.1 - 0.16 10.8 0.4 0.26 10.1 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Transposase_21 PF02992.9 OAJ02414.1 - 1.4e-19 70.1 0.1 2.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Cyt-b5 PF00173.23 OAJ02415.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IncA PF04156.9 OAJ02416.1 - 0.031 13.8 12.1 0.035 13.7 2.7 2.4 2 0 0 2 2 2 0 IncA protein Nup54 PF13874.1 OAJ02416.1 - 0.082 12.5 0.2 0.082 12.5 0.1 2.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TMF_TATA_bd PF12325.3 OAJ02416.1 - 0.18 11.5 9.6 0.25 11.0 0.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1515 PF07439.6 OAJ02416.1 - 0.19 11.5 3.8 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Tropomyosin PF00261.15 OAJ02416.1 - 0.85 8.6 10.7 2.6 7.0 3.9 2.8 3 0 0 3 3 3 0 Tropomyosin Vps51 PF08700.6 OAJ02416.1 - 1.2 8.9 5.8 1.4 8.7 0.1 2.7 3 0 0 3 3 3 0 Vps51/Vps67 Mnd1 PF03962.10 OAJ02416.1 - 2.7 7.5 7.6 26 4.4 2.8 2.3 2 0 0 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 OAJ02416.1 - 5.2 6.9 12.4 11 5.9 2.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 OAJ02416.1 - 5.7 7.0 8.0 5.6 7.0 0.1 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family HECT PF00632.20 OAJ02418.1 - 4.1e-90 302.1 0.0 5.8e-90 301.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF387 PF04079.11 OAJ02418.1 - 0.046 13.0 0.1 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative transcriptional regulators (Ypuh-like) DSHCT PF08148.7 OAJ02419.1 - 2.7e-58 196.1 0.3 6.2e-58 194.9 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 OAJ02419.1 - 7.3e-21 74.3 0.0 1.5e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 OAJ02419.1 - 3.3e-07 29.7 2.9 3.4e-06 26.4 2.0 2.1 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 OAJ02419.1 - 2.4e-06 27.2 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02419.1 - 0.024 14.4 0.0 0.16 11.7 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Ecl1 PF12855.2 OAJ02421.1 - 0.015 14.5 0.3 0.029 13.6 0.2 1.4 1 0 0 1 1 1 0 Life-span regulatory factor NAD_binding_8 PF13450.1 OAJ02422.1 - 1.1e-09 38.1 0.1 2.1e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ02422.1 - 2e-07 30.4 0.0 0.00029 20.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 OAJ02422.1 - 0.00032 20.8 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ02422.1 - 0.013 15.4 0.1 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ02422.1 - 0.024 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 OAJ02422.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 OAJ02422.1 - 0.036 12.5 0.1 0.053 11.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 OAJ02422.1 - 0.042 12.6 0.3 0.063 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 OAJ02422.1 - 0.058 12.2 0.1 0.09 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ02422.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ02422.1 - 0.11 11.5 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 OAJ02422.1 - 0.14 11.0 0.2 0.55 9.0 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3292 PF11696.3 OAJ02423.1 - 1.4e-08 33.1 11.2 9.6e-07 27.0 0.1 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) PRT_C PF08372.5 OAJ02423.1 - 0.0012 18.3 1.7 0.009 15.5 0.2 2.3 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 OAJ02423.1 - 0.039 13.5 5.4 3.1 7.3 2.1 2.3 2 0 0 2 2 2 0 Reticulon PH_BEACH PF14844.1 OAJ02423.1 - 0.12 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Sugar_tr PF00083.19 OAJ02427.1 - 1.2e-27 96.6 8.4 3.8e-22 78.4 0.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ02427.1 - 6.8e-24 84.2 62.4 1.4e-16 60.2 8.5 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF485 PF04341.7 OAJ02427.1 - 0.65 9.7 5.0 14 5.4 1.2 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Peptidase_S10 PF00450.17 OAJ02428.1 - 2.7e-100 336.4 0.0 3.4e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ02428.1 - 0.015 15.1 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Arf PF00025.16 OAJ02430.1 - 1.3e-79 265.4 0.1 1.5e-79 265.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ02430.1 - 3.6e-14 52.3 0.0 4.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 OAJ02430.1 - 2.6e-13 49.7 0.0 2.8e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 OAJ02430.1 - 6e-13 48.2 1.1 1e-09 37.6 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ02430.1 - 3.1e-11 42.8 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ02430.1 - 3.3e-09 37.2 0.0 4.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ02430.1 - 5.5e-06 26.3 0.0 7.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ02430.1 - 0.0053 16.2 0.1 0.042 13.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 OAJ02430.1 - 0.0068 15.4 0.4 0.013 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 OAJ02430.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_S15 PF00312.17 OAJ02431.1 - 5.6e-17 61.2 0.3 5.6e-17 61.2 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 Peptidase_M55 PF04951.8 OAJ02431.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 D-aminopeptidase Ribosomal_L3 PF00297.17 OAJ02432.1 - 1.4e-32 113.1 2.8 5.3e-32 111.2 1.7 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Nbl1_Borealin_N PF10444.4 OAJ02434.1 - 4.3e-14 51.6 0.1 7e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DTHCT PF08070.6 OAJ02434.1 - 0.45 11.2 20.5 1.7 9.3 0.6 2.9 3 0 0 3 3 3 0 DTHCT (NUC029) region Peptidase_S49_N PF08496.5 OAJ02434.1 - 3.7 7.3 8.4 0.55 10.0 2.6 2.0 3 0 0 3 3 3 0 Peptidase family S49 N-terminal GTP_CH_N PF12471.3 OAJ02435.1 - 7e-86 286.8 0.0 1e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 OAJ02435.1 - 2.7e-16 59.2 0.0 4.2e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Tic20 PF09685.5 OAJ02437.1 - 0.43 10.5 2.8 0.63 10.0 2.0 1.2 1 0 0 1 1 1 0 Tic20-like protein DUF3099 PF11298.3 OAJ02437.1 - 2.2 8.1 6.0 1 9.1 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3099) MPLKIP PF15502.1 OAJ02438.1 - 0.46 11.1 6.8 0.56 10.9 4.7 1.1 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein ATG16 PF08614.6 OAJ02438.1 - 0.53 10.0 3.0 0.61 9.8 2.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_GPD PF05954.6 OAJ02438.1 - 0.93 8.6 4.4 0.98 8.5 3.1 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DUF2201_N PF13203.1 OAJ02438.1 - 1.2 8.2 11.1 1.5 7.9 7.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain WLM PF08325.5 OAJ02438.1 - 2.9 7.7 6.6 0.41 10.4 2.0 1.4 2 0 0 2 2 2 0 WLM domain TENA_THI-4 PF03070.11 OAJ02439.1 - 8.8e-16 58.2 0.0 7.9e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family Pyr_redox_3 PF13738.1 OAJ02440.1 - 1.7e-27 96.8 0.1 4e-27 95.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ02440.1 - 2.5e-13 49.0 0.1 5.3e-11 41.4 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ02440.1 - 2.4e-10 40.2 0.0 1.2e-08 34.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ02440.1 - 1.5e-08 33.9 0.6 3.5e-05 22.8 0.0 3.3 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAJ02440.1 - 3e-08 33.7 0.3 0.00011 22.1 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ02440.1 - 3.2e-07 29.6 0.0 0.00079 18.4 0.0 3.4 3 1 1 4 4 4 1 Lycopene cyclase protein DAO PF01266.19 OAJ02440.1 - 2.4e-06 26.7 0.4 0.0015 17.4 0.2 3.7 3 1 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ02440.1 - 2.8e-06 27.1 0.8 0.14 11.9 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ02440.1 - 2.6e-05 23.4 0.3 0.00029 20.0 0.0 2.3 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.19 OAJ02440.1 - 6.3e-05 21.9 0.1 0.00053 18.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ02440.1 - 0.00028 21.2 0.0 0.68 10.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 OAJ02440.1 - 0.0019 16.4 0.1 0.78 7.8 0.1 2.4 2 1 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.15 OAJ02440.1 - 0.0051 16.9 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 OAJ02440.1 - 0.0061 15.4 1.1 0.32 9.8 0.1 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ02440.1 - 0.03 12.8 0.3 0.29 9.5 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 OAJ02440.1 - 0.051 12.2 0.6 2.3 6.7 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 OAJ02440.1 - 0.058 12.4 0.4 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAJ02440.1 - 0.08 13.2 0.0 0.36 11.0 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ02441.1 - 1.4e-18 67.7 0.0 2.1e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ02441.1 - 5.2e-09 34.8 0.1 5.5e-06 24.8 0.1 3.1 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ02441.1 - 1.7e-08 34.3 0.1 6.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAJ02441.1 - 8.1e-08 32.1 0.5 0.00076 19.2 0.1 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ02441.1 - 1e-05 24.6 0.1 0.00052 19.0 0.0 3.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAJ02441.1 - 2.8e-05 24.0 0.0 0.017 15.0 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ02441.1 - 0.0013 17.7 0.0 0.025 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF3712 PF12505.3 OAJ02442.1 - 1.9e-22 79.6 0.1 7.8e-11 42.0 0.0 4.7 3 1 0 3 3 3 3 Protein of unknown function (DUF3712) Ras PF00071.17 OAJ02443.1 - 1.5e-56 190.2 0.3 1.9e-56 189.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ02443.1 - 1e-18 67.9 0.1 1.7e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ02443.1 - 9.1e-14 51.0 0.2 1.1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ02443.1 - 6.6e-07 28.9 0.1 1.3e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ02443.1 - 0.00024 20.3 0.1 0.00028 20.1 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ02443.1 - 0.0017 17.5 0.2 0.002 17.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region BUD22 PF09073.5 OAJ02444.1 - 0.51 9.3 53.3 0.92 8.5 36.9 1.4 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 OAJ02444.1 - 0.96 7.7 60.0 1.7 6.9 41.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 OAJ02444.1 - 1 6.9 15.8 1.2 6.6 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.8 OAJ02444.1 - 1.2 7.2 43.9 1.6 6.8 30.4 1.1 1 0 0 1 1 1 0 Utp14 protein Nop14 PF04147.7 OAJ02444.1 - 1.5 6.6 64.8 2.1 6.1 44.9 1.1 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 OAJ02444.1 - 5.2 5.4 49.6 7.1 4.9 34.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hydrolase_like PF13242.1 OAJ02446.1 - 1.9e-20 72.3 0.1 3.7e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 OAJ02446.1 - 2.7e-16 59.2 0.0 5.5e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase CpcD PF01383.16 OAJ02447.1 - 0.017 15.2 0.1 0.042 14.0 0.1 1.6 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain Aa_trans PF01490.13 OAJ02447.1 - 0.11 10.9 1.0 0.16 10.4 0.7 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Optomotor-blind PF11078.3 OAJ02448.1 - 0.15 12.4 3.8 0.6 10.5 0.2 2.7 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region Pyr_redox PF00070.22 OAJ02449.1 - 1.2e-11 44.8 1.6 1.9e-08 34.5 1.4 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ02449.1 - 1.7e-09 37.8 0.0 0.51 10.1 0.0 4.3 3 1 1 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 OAJ02449.1 - 5e-06 26.3 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ02449.1 - 0.0082 16.0 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ02449.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family ABC2_membrane PF01061.19 OAJ02450.1 - 2.9e-84 281.4 55.0 3.1e-43 147.3 13.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ02450.1 - 1.5e-39 135.4 0.0 3.1e-19 69.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ02450.1 - 6.5e-21 73.9 8.4 7.8e-19 67.2 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 OAJ02450.1 - 3.7e-07 29.4 43.7 4e-05 22.8 7.5 3.2 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 OAJ02450.1 - 9.1e-07 28.8 1.6 1e-06 28.7 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal SMC_N PF02463.14 OAJ02450.1 - 1.3e-06 27.8 0.0 0.0001 21.6 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 OAJ02450.1 - 1.9e-06 28.6 0.0 0.014 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ02450.1 - 2e-06 27.3 0.1 0.0052 16.2 0.1 3.5 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 OAJ02450.1 - 1.8e-05 24.1 0.5 0.0094 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 OAJ02450.1 - 5.6e-05 23.0 1.9 0.055 13.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 OAJ02450.1 - 0.00014 21.9 0.0 0.039 13.9 0.0 2.7 1 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ02450.1 - 0.00016 20.8 0.0 0.01 15.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 OAJ02450.1 - 0.00017 21.0 0.0 0.0088 15.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAJ02450.1 - 0.00021 21.4 0.0 0.41 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ02450.1 - 0.00053 20.0 0.8 0.056 13.4 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF1825 PF08855.5 OAJ02450.1 - 0.0034 17.3 1.0 0.9 9.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1825) AAA_18 PF13238.1 OAJ02450.1 - 0.0055 17.0 3.9 0.28 11.4 0.0 3.5 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ02450.1 - 0.013 14.9 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 OAJ02450.1 - 0.016 14.9 0.6 3.1 7.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 OAJ02450.1 - 0.021 14.9 0.0 15 5.8 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 OAJ02450.1 - 0.024 14.3 0.4 6.3 6.6 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 OAJ02450.1 - 0.026 14.1 0.5 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 OAJ02450.1 - 0.03 14.2 0.1 16 5.4 0.0 3.2 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_28 PF13521.1 OAJ02450.1 - 0.03 14.3 0.1 0.092 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 OAJ02450.1 - 0.066 12.7 0.1 3 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAJ02450.1 - 0.098 12.0 0.1 6.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 OAJ02450.1 - 0.12 12.5 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAJ02450.1 - 0.17 12.1 1.3 0.67 10.2 0.0 2.6 3 0 0 3 3 1 0 AAA domain AAA_15 PF13175.1 OAJ02450.1 - 0.45 9.5 0.0 6.6 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DPBB_1 PF03330.13 OAJ02451.1 - 3.5e-07 30.1 0.2 1.3e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ02451.1 - 0.004 16.8 0.4 0.011 15.4 0.2 1.8 1 0 0 1 1 1 1 Barwin family Sporozoite_P67 PF05642.6 OAJ02451.1 - 0.057 11.2 11.0 0.14 9.9 7.6 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 OAJ02451.1 - 0.18 9.7 12.0 0.27 9.1 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 OAJ02451.1 - 0.24 9.0 8.5 0.3 8.7 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Menin PF05053.8 OAJ02451.1 - 0.45 8.6 10.7 0.67 8.0 7.4 1.2 1 0 0 1 1 1 0 Menin YL1 PF05764.8 OAJ02451.1 - 0.5 9.9 14.9 0.71 9.4 10.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Glycoprotein_G PF00802.14 OAJ02451.1 - 2.7 7.0 26.7 4.8 6.2 18.5 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G Neisseria_TspB PF05616.8 OAJ02451.1 - 3.6 5.8 12.7 4.8 5.4 8.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FNIP_N PF14636.1 OAJ02451.1 - 5.5 7.4 13.5 2 8.8 7.5 1.7 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus SRF-TF PF00319.13 OAJ02452.1 - 1.4e-12 46.5 0.1 2.5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 OAJ02453.1 - 0.14 10.1 3.5 0.18 9.7 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 OAJ02453.1 - 0.2 11.1 13.2 0.29 10.6 9.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ02453.1 - 3 8.2 11.3 5.1 7.4 7.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 OAJ02453.1 - 4.7 7.0 9.5 7.1 6.4 6.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal MAP65_ASE1 PF03999.7 OAJ02459.1 - 2.2e-37 128.9 0.0 4.3e-36 124.7 0.0 2.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.26 OAJ02460.1 - 4.2e-18 64.8 0.3 7.8e-18 63.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2244 PF10003.4 OAJ02462.1 - 0.23 10.8 1.1 3.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TAP_C PF03943.8 OAJ02463.1 - 3.9e-09 35.7 0.0 7.5e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 OAJ02463.1 - 4.5e-08 32.5 3.0 8.4e-06 25.2 0.7 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 OAJ02463.1 - 0.0048 16.8 0.2 12 6.5 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 OAJ02463.1 - 0.03 14.3 0.2 4.6 7.6 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 OAJ02463.1 - 0.057 13.1 1.0 0.71 9.6 0.1 2.3 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 OAJ02463.1 - 0.21 11.7 0.7 47 4.5 0.1 3.4 2 1 1 3 3 3 0 Leucine Rich Repeat NTF2 PF02136.15 OAJ02463.1 - 0.22 11.8 0.2 43 4.4 0.1 2.7 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain TrbI PF03743.9 OAJ02465.1 - 0.068 12.6 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DDHD PF02862.12 OAJ02467.1 - 2.7e-34 118.9 0.0 2.7e-34 118.9 0.0 4.1 3 1 0 3 3 3 1 DDHD domain Abhydrolase_5 PF12695.2 OAJ02467.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DnaJ PF00226.26 OAJ02469.1 - 5.4e-14 51.6 0.1 7e-13 48.1 0.0 2.4 2 1 0 2 2 2 1 DnaJ domain zf-CSL PF05207.8 OAJ02469.1 - 2.7e-09 36.4 0.4 1e-08 34.5 0.0 2.2 2 1 0 2 2 2 1 CSL zinc finger UPF0547 PF10571.4 OAJ02469.1 - 1.4 8.6 5.4 1.5 8.5 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 LRR_4 PF12799.2 OAJ02470.1 - 5.6e-29 99.2 23.4 1.1e-06 28.0 0.1 7.9 4 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ02470.1 - 1.8e-20 72.4 23.9 4.6e-07 29.4 1.4 5.9 3 1 1 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 OAJ02470.1 - 6.6e-12 43.7 27.7 0.13 12.3 0.4 10.4 9 1 1 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 OAJ02470.1 - 4.2e-05 23.0 35.1 0.83 10.1 0.1 10.2 11 0 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 OAJ02470.1 - 0.00026 20.7 20.9 0.74 10.0 0.2 8.5 7 1 2 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 OAJ02470.1 - 0.063 12.8 15.3 0.6 9.6 0.3 4.6 4 1 0 5 5 5 0 Leucine-rich repeat Tubulin_3 PF14881.1 OAJ02472.1 - 1.2e-27 96.5 14.2 2.5e-18 66.2 0.7 4.2 2 1 2 4 4 4 4 Tubulin domain Misat_Tub_SegII PF10644.4 OAJ02472.1 - 1.2e-26 93.0 0.0 4.7e-26 91.0 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 OAJ02472.1 - 0.17 11.6 0.0 0.73 9.6 0.0 1.9 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain ING PF12998.2 OAJ02473.1 - 5.5e-10 39.4 0.3 1.3e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ02473.1 - 8.3e-09 35.0 8.6 1.4e-08 34.2 5.9 1.4 1 0 0 1 1 1 1 PHD-finger Rep_fac_C PF08542.6 OAJ02474.1 - 3.1e-18 65.5 0.2 7.5e-18 64.3 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAJ02474.1 - 4.5e-12 45.9 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 OAJ02474.1 - 8.8e-05 22.7 0.2 0.0003 21.0 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ02474.1 - 0.00043 20.4 0.1 0.002 18.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ02474.1 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ02474.1 - 0.0028 16.7 0.2 0.51 9.3 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 OAJ02474.1 - 0.0089 15.4 0.1 0.043 13.2 0.0 2.0 1 1 1 2 2 2 1 AAA-like domain Sigma54_activ_2 PF14532.1 OAJ02474.1 - 0.011 15.7 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SNF2_N PF00176.18 OAJ02474.1 - 0.032 13.0 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_16 PF13191.1 OAJ02474.1 - 0.034 14.1 2.6 0.15 12.0 0.1 2.8 2 2 0 2 2 2 0 AAA ATPase domain DUF1254 PF06863.7 OAJ02474.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) DUF2454 PF10521.4 OAJ02475.1 - 5.2e-10 38.7 0.0 4.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2454) Complex1_LYR PF05347.10 OAJ02476.1 - 5.1e-08 32.5 0.6 1.3e-07 31.2 0.4 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arm PF00514.18 OAJ02476.1 - 0.00026 20.7 4.5 0.31 10.9 0.1 3.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Complex1_LYR_1 PF13232.1 OAJ02476.1 - 0.0021 18.2 0.6 0.0056 16.8 0.4 1.7 1 0 0 1 1 1 1 Complex1_LYR-like SET PF00856.23 OAJ02477.1 - 1.1e-11 45.3 0.0 2.7e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 OAJ02477.1 - 2.1e-11 43.8 0.2 3.7e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CENP-B_dimeris PF09026.5 OAJ02477.1 - 0.067 13.4 5.5 0.26 11.5 3.8 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ02477.1 - 1.4 8.4 8.9 2 7.9 5.1 1.9 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 OAJ02477.1 - 2.3 8.5 9.1 24 5.3 4.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 OAJ02477.1 - 4.6 6.3 5.0 8.1 5.5 3.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 OAJ02477.1 - 4.7 5.8 11.9 2.7 6.6 6.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) EAF PF09816.4 OAJ02478.1 - 3.1e-13 49.6 0.0 9.1e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription elongation factor Daxx PF03344.10 OAJ02478.1 - 0.004 15.7 42.2 0.0063 15.0 5.5 2.4 2 0 0 2 2 2 2 Daxx Family BUD22 PF09073.5 OAJ02478.1 - 0.18 10.8 36.3 0.12 11.3 12.6 2.2 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.7 OAJ02478.1 - 0.19 9.6 45.4 0.22 9.3 15.2 2.1 2 0 0 2 2 2 0 Nop14-like family Cwf_Cwc_15 PF04889.7 OAJ02478.1 - 3 7.5 46.9 2.3 7.8 6.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.5 OAJ02478.1 - 3.5 6.7 29.8 0.47 9.6 1.0 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SGT1 PF07093.6 OAJ02478.1 - 6.2 5.0 24.9 0.27 9.5 3.7 2.1 2 0 0 2 2 2 0 SGT1 protein DUF4505 PF14956.1 OAJ02479.1 - 5.4e-29 101.1 0.0 1.6e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Arm PF00514.18 OAJ02480.1 - 2.1e-08 33.6 20.2 0.55 10.1 0.0 10.5 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 OAJ02480.1 - 1.7e-07 30.7 12.0 1.9 8.7 0.0 8.8 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.1 OAJ02480.1 - 5.3e-05 23.4 13.0 1.4 9.2 0.0 6.8 7 1 0 7 7 7 2 HEAT repeats DUF4530 PF15039.1 OAJ02480.1 - 0.09 12.6 1.0 0.29 11.0 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) ATP-synt_ab PF00006.20 OAJ02481.1 - 1.2e-63 214.4 0.0 2.8e-63 213.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 OAJ02481.1 - 1.9e-24 85.6 1.7 6e-24 84.0 1.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 OAJ02481.1 - 8.2e-23 81.0 0.8 1.4e-22 80.2 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Arch_ATPase PF01637.13 OAJ02481.1 - 0.0021 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 OAJ02481.1 - 0.0053 16.1 0.1 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ02481.1 - 0.0094 15.0 0.2 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 OAJ02481.1 - 0.017 14.2 0.1 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ02481.1 - 0.021 14.9 0.0 0.15 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 OAJ02481.1 - 0.021 14.4 0.3 0.96 9.1 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 OAJ02481.1 - 0.026 14.1 0.1 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 OAJ02481.1 - 0.028 14.4 1.0 0.081 12.9 0.0 2.3 2 2 1 3 3 3 0 AAA ATPase domain AAA PF00004.24 OAJ02481.1 - 0.036 14.2 0.0 0.22 11.7 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 OAJ02481.1 - 0.064 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 OAJ02481.1 - 0.096 11.5 0.1 0.096 11.5 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 OAJ02481.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TPR_11 PF13414.1 OAJ02485.1 - 1.7e-08 34.0 2.4 0.23 11.1 0.1 5.4 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 OAJ02485.1 - 5.6e-07 29.4 5.7 0.098 12.6 0.3 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02485.1 - 0.00046 19.8 0.7 5.2 7.2 0.7 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02485.1 - 0.38 11.4 19.5 21 6.0 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ02485.1 - 1.1 10.0 14.2 6.1 7.6 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ02485.1 - 2.4 8.7 7.4 51 4.6 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3184 PF11380.3 OAJ02486.1 - 3.6e-20 71.5 8.4 1.8e-09 36.1 0.1 4.0 1 1 3 4 4 4 4 Protein of unknown function (DUF3184) CMAS PF02353.15 OAJ02487.1 - 8e-62 208.7 0.0 2.3e-51 174.4 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 OAJ02487.1 - 3.6e-10 40.4 0.0 7.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ02487.1 - 5e-08 33.3 0.0 1.1e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ02487.1 - 3.5e-07 30.0 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ02487.1 - 6.4e-07 29.0 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ02487.1 - 2.6e-05 24.2 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ02487.1 - 0.00057 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ02487.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 OAJ02487.1 - 0.005 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 OAJ02487.1 - 0.01 15.4 0.0 0.034 13.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) PCMT PF01135.14 OAJ02487.1 - 0.05 13.1 0.0 0.32 10.4 0.0 2.0 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 OAJ02487.1 - 0.051 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 OAJ02487.1 - 0.074 13.8 0.0 0.17 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1034 PF06280.7 OAJ02488.1 - 3.7e-07 30.5 0.0 7.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Peptidase_S8 PF00082.17 OAJ02489.1 - 8.8e-56 189.1 5.9 9e-38 130.0 1.1 2.3 2 0 0 2 2 2 2 Subtilase family ABC_membrane_2 PF06472.10 OAJ02490.1 - 7.9e-99 330.3 5.8 1.1e-98 329.8 4.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ02490.1 - 3.5e-17 62.9 0.0 7.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 OAJ02490.1 - 0.0028 16.7 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAJ02490.1 - 0.0037 18.0 0.0 0.011 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ02490.1 - 0.0043 16.2 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 OAJ02490.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 OAJ02490.1 - 0.019 15.1 0.1 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 OAJ02490.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 OAJ02490.1 - 0.036 13.5 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ02490.1 - 0.043 14.1 0.2 0.1 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 OAJ02490.1 - 0.082 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ02490.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ02490.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 OAJ02490.1 - 0.12 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ02490.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.3 OAJ02490.1 - 0.21 8.8 0.2 0.44 7.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) adh_short PF00106.20 OAJ02491.1 - 2.7e-12 46.9 0.4 5.8e-11 42.5 0.3 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ02491.1 - 1.2e-05 25.0 0.1 4.8e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ02491.1 - 0.083 12.8 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 OAJ02491.1 - 0.094 12.8 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 OAJ02491.1 - 0.52 10.1 2.4 0.56 10.0 0.3 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S8 PF00082.17 OAJ02492.1 - 1.5e-39 135.8 1.2 2.2e-39 135.2 0.8 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ02492.1 - 8e-08 32.6 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF3210 PF11489.3 OAJ02493.1 - 0.48 9.0 6.5 1.9 7.0 4.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3210) TPR_14 PF13428.1 OAJ02494.1 - 1.7e-06 28.1 27.1 0.1 13.2 0.1 8.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ02494.1 - 5e-06 26.0 16.4 0.32 10.6 0.0 6.8 5 3 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 OAJ02494.1 - 8.6e-06 25.6 30.4 0.13 12.1 0.1 7.1 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ02494.1 - 0.00011 22.7 27.4 0.017 15.7 1.1 7.0 5 2 1 6 6 6 3 Tetratricopeptide repeat Apc5 PF12862.2 OAJ02494.1 - 0.014 15.2 0.6 0.82 9.5 0.1 3.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 OAJ02494.1 - 0.025 14.4 26.6 15 5.7 0.0 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ02494.1 - 0.031 14.6 26.9 0.16 12.3 0.0 7.4 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ02494.1 - 0.061 13.5 7.0 13 6.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ02494.1 - 0.2 11.3 8.0 59 3.5 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ02494.1 - 0.77 10.3 17.5 6.7 7.4 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Dicty_CAR PF05462.6 OAJ02496.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor MFS_1 PF07690.11 OAJ02498.1 - 8.2e-30 103.6 75.2 7.7e-25 87.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 OAJ02499.1 - 2.8e-05 23.6 0.0 9.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ02499.1 - 3.5e-05 23.6 0.1 0.00048 19.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sulfatase PF00884.18 OAJ02500.1 - 2.1e-56 191.4 0.0 2.6e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 OAJ02500.1 - 0.00018 21.8 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 C-terminal region of aryl-sulfatase DUF229 PF02995.12 OAJ02500.1 - 0.00032 19.2 0.0 0.00041 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 OAJ02500.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 OAJ02500.1 - 0.0055 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) SNO PF01174.14 OAJ02501.1 - 5e-50 169.7 0.0 1.9e-39 135.2 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 OAJ02501.1 - 1.5e-08 34.3 0.2 2.3e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 OAJ02501.1 - 0.00061 19.2 0.1 0.00096 18.6 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 OAJ02501.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 OAJ02501.1 - 0.063 12.5 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative amidotransferase BPL_N PF09825.4 OAJ02501.1 - 0.22 10.3 0.0 2 7.1 0.0 1.9 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Herpes_capsid PF06112.6 OAJ02501.1 - 4.1 7.4 6.5 9.8 6.2 4.5 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_19 PF14559.1 OAJ02502.1 - 0.0039 17.4 2.2 27 5.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ02502.1 - 2.3 9.0 12.0 10 7.0 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat PRP1_N PF06424.7 OAJ02502.1 - 7 6.9 10.5 15 5.9 7.3 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Proteasome PF00227.21 OAJ02504.1 - 1e-43 148.8 0.0 1.3e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ02504.1 - 5.9e-09 35.0 1.3 1.8e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature APH PF01636.18 OAJ02506.1 - 0.0023 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Steroid_dh PF02544.11 OAJ02511.1 - 1.1e-34 119.3 1.1 2.2e-34 118.4 0.7 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 OAJ02511.1 - 2.4e-07 30.0 0.0 3.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.7 OAJ02511.1 - 1.8e-06 27.4 0.6 4.2e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) COX6A PF02046.10 OAJ02511.1 - 0.00052 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ICMT PF04140.9 OAJ02511.1 - 0.0098 16.0 0.1 0.022 14.9 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ02511.1 - 0.013 15.6 0.9 0.013 15.6 0.6 2.2 1 1 2 3 3 3 0 Phospholipid methyltransferase GMC_oxred_N PF00732.14 OAJ02512.1 - 2.1e-51 174.8 0.0 3.2e-51 174.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ02512.1 - 2.9e-37 128.1 0.0 6.9e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ02512.1 - 0.00061 18.7 0.5 0.0019 17.1 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ02512.1 - 0.0024 16.8 0.5 0.0049 15.8 0.4 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 OAJ02512.1 - 0.0029 17.5 0.2 0.013 15.5 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ02512.1 - 0.0046 15.8 0.7 0.12 11.1 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ02512.1 - 0.0048 16.8 0.9 0.019 14.8 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ02512.1 - 0.017 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family SLAC1 PF03595.12 OAJ02513.1 - 3.3e-64 216.6 45.5 4.4e-64 216.2 31.5 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4540 PF15073.1 OAJ02513.1 - 0.29 11.6 2.2 1.9 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4540) adh_short PF00106.20 OAJ02514.1 - 2.2e-12 47.2 0.2 9.2e-11 41.9 0.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ02514.1 - 2.8e-06 27.1 0.1 1.2e-05 25.0 0.1 2.1 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ02514.1 - 0.0084 15.8 0.7 0.023 14.4 0.5 1.8 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 OAJ02514.1 - 0.037 14.1 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ecl1 PF12855.2 OAJ02515.1 - 2.8e-07 29.7 0.0 0.017 14.4 0.0 2.5 2 0 0 2 2 2 2 Life-span regulatory factor Aa_trans PF01490.13 OAJ02516.1 - 4.8e-45 153.7 31.9 5.7e-45 153.5 22.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Anoctamin PF04547.7 OAJ02516.1 - 0.017 13.7 0.6 0.017 13.7 0.4 2.2 2 0 0 2 2 2 0 Calcium-activated chloride channel Sex_peptide PF08138.6 OAJ02516.1 - 0.15 11.9 0.1 8.8 6.2 0.0 3.3 3 0 0 3 3 3 0 Sex peptide (SP) family CRAL_TRIO PF00650.15 OAJ02517.1 - 1.2e-34 119.1 0.0 2.7e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ02517.1 - 1.1e-07 31.8 0.2 2.7e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ThiS PF02597.15 OAJ02517.1 - 1.5e-07 31.6 0.1 1.4e-06 28.6 0.1 2.5 2 0 0 2 2 2 1 ThiS family MutL_C PF08676.6 OAJ02519.1 - 1.2e-06 28.1 0.0 6.1e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 OAJ02519.1 - 0.0011 18.6 0.0 0.0037 16.9 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ02519.1 - 0.0015 18.1 0.0 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 OAJ02520.1 - 2.1e-62 210.6 0.0 2.7e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02520.1 - 3e-33 114.9 0.0 4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02520.1 - 6.8e-08 31.8 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ02520.1 - 0.0003 20.6 0.1 0.00071 19.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ02520.1 - 0.0047 16.0 0.0 0.0092 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family vMSA PF00695.14 OAJ02520.1 - 0.065 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus F_bP_aldolase PF01116.15 OAJ02522.1 - 1.9e-100 335.6 0.0 2.2e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DER1 PF04511.10 OAJ02523.1 - 3e-27 95.3 0.3 3.9e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 OAJ02523.1 - 0.17 11.8 3.9 0.35 10.8 2.7 1.6 1 0 0 1 1 1 0 Rhomboid family zf-CCCH PF00642.19 OAJ02524.1 - 5.5e-09 35.4 2.5 1e-08 34.6 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 OAJ02524.1 - 4.6e-08 32.9 10.9 8e-08 32.1 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ02524.1 - 5.3e-08 32.4 6.1 8.6e-08 31.7 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ02524.1 - 1.2e-06 28.1 8.1 2e-06 27.5 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ02524.1 - 5.6e-06 25.9 9.6 9.4e-06 25.2 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ02524.1 - 2.5e-05 24.0 8.6 5.3e-05 23.0 6.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 OAJ02524.1 - 3.8e-05 23.2 10.0 6.9e-05 22.4 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ02524.1 - 7.5e-05 22.3 6.0 0.00019 21.0 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 OAJ02524.1 - 0.004 16.6 4.0 0.007 15.8 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 OAJ02524.1 - 0.17 12.0 5.1 0.45 10.6 3.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Nup88 PF10168.4 OAJ02525.1 - 6.8e-08 30.8 0.7 0.084 10.7 0.0 4.1 4 0 0 4 4 4 4 Nuclear pore component SlyX PF04102.7 OAJ02525.1 - 4.5 7.7 10.6 4.6 7.6 0.2 3.5 3 0 0 3 3 3 0 SlyX Gaa1 PF04114.9 OAJ02526.1 - 1.2e-42 146.2 2.7 6.8e-20 71.2 0.0 4.0 4 0 0 4 4 4 3 Gaa1-like, GPI transamidase component GMC_oxred_N PF00732.14 OAJ02526.1 - 7.2e-41 140.2 0.1 6e-40 137.2 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ02526.1 - 1.4e-29 103.2 0.0 2.8e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase S10_plectin PF03501.10 OAJ02527.1 - 7.5e-39 131.4 0.1 1e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_S25 PF03297.10 OAJ02528.1 - 1.8e-40 137.1 2.3 2.2e-40 136.9 1.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 OAJ02528.1 - 0.027 13.8 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 OAJ02528.1 - 0.053 13.2 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 MarR family MTS PF05175.9 OAJ02528.1 - 0.092 12.1 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Aldedh PF00171.17 OAJ02529.1 - 3.4e-155 516.8 0.0 5.5e-155 516.2 0.0 1.3 2 0 0 2 2 2 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ02529.1 - 9.9e-05 21.2 0.0 0.00015 20.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) V-ATPase_C PF03223.10 OAJ02530.1 - 4.2e-120 401.0 5.4 4.8e-120 400.8 3.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF3818 PF12825.2 OAJ02531.1 - 2.7e-38 131.5 0.0 4.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ02531.1 - 1.1e-19 70.3 0.0 2.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 PX-associated Pyr_redox_3 PF13738.1 OAJ02532.1 - 1.9e-17 63.9 0.0 5.2e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 OAJ02532.1 - 6.3e-10 37.8 0.1 6.6e-07 27.9 0.1 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 OAJ02532.1 - 2.2e-07 30.8 0.0 9.9e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 OAJ02532.1 - 3.4e-07 30.1 0.1 0.1 12.3 0.0 3.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 OAJ02532.1 - 4.1e-06 25.9 0.0 0.00029 19.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 OAJ02532.1 - 9.6e-06 25.6 0.0 0.18 11.6 0.0 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 OAJ02532.1 - 0.017 14.0 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ02532.1 - 0.024 13.5 0.0 0.34 9.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 OAJ02532.1 - 0.071 13.2 0.0 8.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 OAJ02532.1 - 0.22 10.5 0.1 1 8.4 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Oxidored_q6 PF01058.17 OAJ02533.1 - 1.7e-22 79.4 0.1 3e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Hydrophobin PF01185.13 OAJ02538.1 - 0.02 15.3 6.2 0.39 11.1 4.4 2.0 1 1 1 2 2 2 0 Fungal hydrophobin CarbpepA_inh PF02977.10 OAJ02538.1 - 0.05 13.1 1.0 0.05 13.1 0.7 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Phage_integrase PF00589.17 OAJ02539.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family RVT_1 PF00078.22 OAJ02539.1 - 0.02 14.2 0.0 0.14 11.4 0.0 2.3 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_int_SAM_4 PF13495.1 OAJ02539.1 - 0.09 13.1 0.1 0.59 10.5 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain AAA PF00004.24 OAJ02540.1 - 2.2e-40 137.9 0.0 5.8e-40 136.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ02540.1 - 0.00022 21.2 3.4 0.0027 17.7 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 OAJ02540.1 - 0.00052 20.1 0.4 0.018 15.1 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ02540.1 - 0.0007 19.3 0.8 0.0062 16.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ02540.1 - 0.00091 18.3 0.0 0.002 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 OAJ02540.1 - 0.0012 18.1 0.0 0.008 15.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.9 OAJ02540.1 - 0.0012 18.7 2.1 0.0066 16.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ02540.1 - 0.0023 18.7 0.1 0.0083 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ02540.1 - 0.0072 16.0 0.1 0.024 14.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 OAJ02540.1 - 0.0074 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ02540.1 - 0.0083 15.3 0.1 0.039 13.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 OAJ02540.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 OAJ02540.1 - 0.021 14.3 3.1 1.1 8.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 OAJ02540.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ02540.1 - 0.054 12.8 2.9 0.19 11.0 0.1 2.6 2 1 0 3 3 3 0 AAA domain DUF815 PF05673.8 OAJ02540.1 - 0.062 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 OAJ02540.1 - 0.099 12.2 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain MIF4G_like_2 PF09090.6 OAJ02540.1 - 0.44 9.7 2.5 0.76 8.9 1.7 1.3 1 0 0 1 1 1 0 MIF4G like Nucleoplasmin PF03066.10 OAJ02541.1 - 0.45 10.0 4.1 0.79 9.2 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ02541.1 - 4.3 5.1 6.4 6.3 4.5 4.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF1860 PF08949.5 OAJ02541.1 - 4.9 6.6 12.1 0.1 12.1 3.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) NOA36 PF06524.7 OAJ02541.1 - 5.2 6.2 9.9 8.9 5.4 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein Aminotran_1_2 PF00155.16 OAJ02542.1 - 3.3e-33 115.1 0.0 1.1e-32 113.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ02542.1 - 0.059 12.5 0.0 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase CMD PF02627.15 OAJ02543.1 - 0.012 15.4 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Helicase_C PF00271.26 OAJ02545.1 - 1.3e-20 72.9 0.1 4.4e-19 68.1 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02545.1 - 1.5e-18 67.2 0.0 5.2e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ02545.1 - 1.6e-17 63.4 0.0 4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase E3_binding PF02817.12 OAJ02545.1 - 0.03 13.9 0.0 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 e3 binding domain HOOK PF05622.7 OAJ02546.1 - 0.0034 15.2 1.7 0.0034 15.2 1.2 1.7 2 0 0 2 2 2 1 HOOK protein TMF_DNA_bd PF12329.3 OAJ02546.1 - 0.007 16.1 2.5 0.007 16.1 1.8 3.2 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.4 OAJ02546.1 - 0.0084 16.1 7.7 0.014 15.4 0.0 2.9 3 0 0 3 3 3 1 Predicted coiled-coil domain-containing protein CCDC144C PF14915.1 OAJ02546.1 - 0.011 14.6 0.4 0.011 14.6 0.3 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Orbi_NS3 PF01616.11 OAJ02546.1 - 0.022 13.7 2.3 1.3 7.9 0.2 2.4 2 0 0 2 2 2 0 Orbivirus NS3 DUF2353 PF09789.4 OAJ02546.1 - 0.028 13.6 0.4 0.028 13.6 0.2 1.5 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) IncA PF04156.9 OAJ02546.1 - 0.18 11.4 15.5 0.29 10.7 0.8 3.1 3 0 0 3 3 3 0 IncA protein TBPIP PF07106.8 OAJ02546.1 - 0.18 11.3 9.0 1.5 8.3 0.1 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 OAJ02546.1 - 0.26 11.0 17.5 1.7 8.4 0.6 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Latarcin PF10279.4 OAJ02546.1 - 0.37 11.0 7.8 1.9 8.7 0.0 2.8 2 1 0 2 2 2 0 Latarcin precursor FH2 PF02181.18 OAJ02546.1 - 0.39 9.5 2.0 0.4 9.5 0.5 1.6 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF4200 PF13863.1 OAJ02546.1 - 0.45 10.4 12.4 1.1 9.1 0.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) HAUS5 PF14817.1 OAJ02546.1 - 0.52 8.7 8.1 0.12 10.9 1.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 5 APG6 PF04111.7 OAJ02546.1 - 1.4 7.8 8.9 0.66 8.9 0.4 2.8 3 0 0 3 3 3 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 OAJ02546.1 - 1.7 8.4 10.3 1.1 9.0 1.2 3.0 3 0 0 3 3 3 0 Axonemal dynein light chain DivIVA PF05103.8 OAJ02546.1 - 1.9 8.5 14.5 0.059 13.4 1.4 3.0 3 0 0 3 3 3 0 DivIVA protein DUF972 PF06156.8 OAJ02546.1 - 5.1 7.4 11.3 28 5.1 1.3 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF972) Filament PF00038.16 OAJ02546.1 - 5.2 6.4 15.4 2.7 7.3 1.7 3.0 3 0 0 3 3 3 0 Intermediate filament protein ALIX_LYPXL_bnd PF13949.1 OAJ02546.1 - 6 5.7 12.6 2.1 7.2 0.1 2.8 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV Auxin_repressed PF05564.7 OAJ02547.1 - 0.23 12.0 3.8 0.35 11.4 2.2 1.8 1 1 1 2 2 2 0 Dormancy/auxin associated protein UDPGT PF00201.13 OAJ02549.1 - 4.6e-13 48.5 0.1 7.8e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.8 OAJ02549.1 - 0.068 13.3 0.7 3.1 8.0 0.5 2.7 1 1 0 1 1 1 0 GHMP kinases C terminal RCC1 PF00415.13 OAJ02550.1 - 1.2e-16 60.6 7.4 8.1e-05 22.7 0.0 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ02550.1 - 4.8e-16 57.8 15.8 3.4e-05 23.3 0.0 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat zf-AN1 PF01428.11 OAJ02551.1 - 3.5e-16 58.8 16.6 8.5e-11 41.5 2.9 3.0 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 OAJ02551.1 - 0.023 14.9 12.5 0.61 10.3 1.7 3.2 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain IBR PF01485.16 OAJ02551.1 - 0.056 13.3 12.8 0.057 13.2 1.5 2.6 2 1 0 2 2 2 0 IBR domain C1_4 PF07975.7 OAJ02551.1 - 0.57 10.2 7.5 5 7.2 0.1 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-trcl PF13451.1 OAJ02551.1 - 5.3 6.7 7.7 8.5 6.1 0.3 2.8 2 1 0 2 2 2 0 Probable zinc-binding domain G-gamma PF00631.17 OAJ02552.1 - 3.6e-22 77.8 0.0 4.1e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain RasGEF PF00617.14 OAJ02553.1 - 8.3e-40 136.5 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ02553.1 - 5.2e-07 29.7 0.1 1.2e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 OAJ02553.1 - 9.4e-06 26.1 0.0 2.9e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 OAJ02553.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.16 OAJ02553.1 - 0.33 10.1 0.0 0.83 8.8 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family SYCE1 PF15233.1 OAJ02554.1 - 0.021 14.7 16.3 0.016 15.1 10.0 1.8 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 KNOX2 PF03791.8 OAJ02554.1 - 0.038 13.2 1.2 5 6.4 0.2 2.6 2 0 0 2 2 2 0 KNOX2 domain Prominin PF05478.6 OAJ02554.1 - 0.23 8.9 2.3 0.32 8.4 1.6 1.2 1 0 0 1 1 1 0 Prominin IncA PF04156.9 OAJ02554.1 - 1.7 8.1 16.5 6.5 6.3 3.3 2.5 1 1 1 2 2 2 0 IncA protein OmpH PF03938.9 OAJ02554.1 - 5 7.0 13.1 8.3 6.3 8.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Metal_resist PF13801.1 OAJ02554.1 - 5.6 6.9 11.1 0.54 10.2 1.8 2.8 1 1 1 2 2 2 0 Heavy-metal resistance YtxH PF12732.2 OAJ02554.1 - 8.7 6.7 7.6 3.7 7.9 1.7 2.6 2 1 0 2 2 2 0 YtxH-like protein Transposase_21 PF02992.9 OAJ02555.1 - 2.5e-22 79.0 0.0 4.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02555.1 - 0.071 12.5 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) OmpH PF03938.9 OAJ02556.1 - 0.0068 16.3 0.2 0.078 12.9 0.0 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) PAT1 PF09770.4 OAJ02556.1 - 9.7 4.2 40.0 1.7 6.8 12.9 2.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UMP1 PF05348.6 OAJ02557.1 - 5.9e-18 65.0 0.7 7.2e-18 64.7 0.5 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Cytidylate_kin PF02224.13 OAJ02558.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase DJ-1_PfpI PF01965.19 OAJ02558.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family BIR PF00653.16 OAJ02559.1 - 8.2e-28 96.6 1.2 8.1e-20 71.0 0.7 2.9 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain Hydrophobin PF01185.13 OAJ02560.1 - 1.5 9.3 5.5 17 5.9 0.3 2.1 1 1 0 2 2 2 0 Fungal hydrophobin Histone PF00125.19 OAJ02561.1 - 9e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF2664 PF10867.3 OAJ02561.1 - 0.089 13.4 0.7 0.48 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) Med9 PF07544.8 OAJ02563.1 - 0.0065 16.1 0.7 3.6 7.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Gon7 PF08738.5 OAJ02563.1 - 0.015 15.2 0.4 0.047 13.6 0.3 1.8 1 0 0 1 1 1 0 Gon7 family Muted PF14942.1 OAJ02563.1 - 0.026 14.3 0.3 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein EamA PF00892.15 OAJ02563.1 - 3.7 7.5 9.6 1.2 9.1 0.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family UDPGT PF00201.13 OAJ02564.1 - 1.1e-12 47.3 0.1 1.8e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.8 OAJ02564.1 - 0.044 13.9 0.9 2.5 8.3 0.4 2.9 3 1 0 3 3 3 0 GHMP kinases C terminal zf-IS66 PF13005.2 OAJ02573.1 - 1.6 8.7 7.6 9.1 6.3 0.1 3.6 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Cation_efflux PF01545.16 OAJ02574.1 - 6.1e-37 127.2 8.0 8.4e-37 126.7 5.6 1.2 1 0 0 1 1 1 1 Cation efflux family SUZ PF12752.2 OAJ02574.1 - 7.6 7.1 21.2 11 6.6 4.4 3.3 2 0 0 2 2 2 0 SUZ domain Mmp37 PF09139.6 OAJ02576.1 - 1.8e-98 329.6 0.0 3.6e-98 328.6 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 FGGY_C PF02782.11 OAJ02577.1 - 2.3e-44 151.4 0.1 3.6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 OAJ02577.1 - 3.8e-24 85.3 0.1 3.9e-23 82.0 0.1 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 OAJ02577.1 - 1.2e-05 24.8 0.4 4.8e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 OAJ02577.1 - 0.0077 15.5 0.0 0.037 13.3 0.0 1.9 2 0 0 2 2 2 1 Hexokinase SNF2_N PF00176.18 OAJ02578.1 - 1.2e-56 191.7 0.0 1.8e-55 187.8 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ02578.1 - 3.2e-10 39.7 0.0 7.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 OAJ02578.1 - 7.5e-09 35.1 5.7 1.4e-08 34.2 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ02578.1 - 1.4e-08 34.5 6.6 2.7e-08 33.6 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ02578.1 - 6.7e-08 32.2 4.9 1.2e-07 31.4 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 OAJ02578.1 - 9.4e-07 28.6 8.1 1.9e-06 27.6 5.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ02578.1 - 1.8e-05 24.3 2.5 3.3e-05 23.4 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ02578.1 - 3.7e-05 23.3 3.4 7e-05 22.4 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ02578.1 - 6.8e-05 22.5 4.5 0.00016 21.3 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 OAJ02578.1 - 0.001 19.1 0.4 0.0027 17.7 0.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 OAJ02578.1 - 0.17 11.6 3.2 0.36 10.6 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 OAJ02578.1 - 0.81 9.2 3.9 1.6 8.2 2.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger SMP PF04927.7 OAJ02579.1 - 3.9e-05 23.5 2.7 3.9e-05 23.5 1.9 1.8 2 0 0 2 2 2 1 Seed maturation protein GRP PF07172.6 OAJ02579.1 - 0.16 12.4 14.1 0.24 11.9 9.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family Med4 PF10018.4 OAJ02580.1 - 2.8e-19 69.2 9.7 2.8e-19 69.2 6.7 1.7 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TBPIP PF07106.8 OAJ02580.1 - 0.086 12.3 2.9 0.15 11.5 2.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FAST_1 PF06743.10 OAJ02580.1 - 0.086 12.5 1.0 0.2 11.3 0.7 1.6 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Med11 PF10280.4 OAJ02580.1 - 4.4 7.3 8.9 2.2 8.3 4.2 2.1 1 1 1 2 2 2 0 Mediator complex protein Ribosomal_L11 PF00298.14 OAJ02581.1 - 0.085 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain DUF1772 PF08592.6 OAJ02582.1 - 7.6e-11 41.9 3.1 8.3e-11 41.7 1.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Flavi_M PF01004.14 OAJ02582.1 - 0.093 12.1 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Adaptin_N PF01602.15 OAJ02584.1 - 5.3e-18 64.6 0.0 6.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HeLo PF14479.1 OAJ02585.1 - 2.2e-06 27.5 0.9 0.093 12.4 0.0 3.0 3 0 0 3 3 3 2 Prion-inhibition and propagation DUF1772 PF08592.6 OAJ02586.1 - 1.3e-12 47.6 2.6 2e-12 47.0 1.8 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) IncA PF04156.9 OAJ02587.1 - 0.051 13.1 0.2 0.22 11.1 0.1 2.1 1 0 0 1 1 1 0 IncA protein RVT_2 PF07727.9 OAJ02588.1 - 6.1e-70 234.9 0.0 9.1e-70 234.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02588.1 - 9.4e-27 93.5 0.0 3e-26 91.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain UBN2_2 PF14227.1 OAJ02588.1 - 9.4e-09 34.8 0.0 1.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ02588.1 - 3e-06 26.7 0.0 8.6e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ02588.1 - 6e-06 26.0 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 OAJ02588.1 - 0.00057 19.6 4.5 0.0011 18.7 3.1 1.5 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.1 OAJ02588.1 - 0.00075 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.1 OAJ02588.1 - 0.032 13.9 0.2 0.085 12.6 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ02588.1 - 0.46 10.0 3.4 0.39 10.2 0.6 2.0 2 0 0 2 2 2 0 Zinc knuckle Abhydrolase_5 PF12695.2 OAJ02590.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Phage_integrase PF00589.17 OAJ02591.1 - 0.00071 19.2 0.3 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family DUF601 PF04642.7 OAJ02591.1 - 0.28 10.5 3.9 0.5 9.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 RNase_H PF00075.19 OAJ02592.1 - 2e-14 54.0 0.0 3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 OAJ02592.1 - 0.024 14.3 0.2 0.06 13.1 0.2 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like Peroxidase_2 PF01328.12 OAJ02593.1 - 3.7e-18 65.2 0.8 8.9e-18 64.0 0.6 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 DUF552 PF04472.7 OAJ02593.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_12 PF13087.1 OAJ02595.1 - 5.7e-33 113.9 0.0 1.1e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ02595.1 - 3.7e-30 105.2 3.9 1.5e-29 103.2 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ02595.1 - 4.2e-10 39.2 0.0 1.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ02595.1 - 9.9e-08 31.7 1.9 0.00027 20.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.4 OAJ02595.1 - 1e-05 24.6 0.6 9e-05 21.6 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAJ02595.1 - 0.00062 19.8 7.3 0.0021 18.0 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ02595.1 - 0.02 15.0 0.0 0.08 13.0 0.0 2.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 OAJ02595.1 - 0.021 14.0 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 OAJ02595.1 - 0.063 13.1 0.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 OAJ02595.1 - 0.082 12.6 0.0 4.3 7.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DHC_N1 PF08385.7 OAJ02600.1 - 1.4e-170 568.5 11.0 1.4e-170 568.5 7.7 3.3 4 0 0 4 4 4 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 OAJ02600.1 - 2.3e-128 428.2 3.2 2.3e-128 428.2 2.2 3.2 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 OAJ02600.1 - 7.6e-83 277.5 0.0 3.7e-82 275.2 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 OAJ02600.1 - 1.4e-27 96.0 0.0 4.2e-13 49.2 0.0 5.9 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 OAJ02600.1 - 2.7e-25 88.8 0.0 5.3e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 OAJ02600.1 - 1.8e-20 73.1 0.2 1.1e-18 67.3 0.0 3.9 6 0 0 6 6 5 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 OAJ02600.1 - 3.7e-14 52.9 0.1 0.016 15.3 0.0 5.8 5 0 0 5 5 5 3 AAA domain AAA PF00004.24 OAJ02600.1 - 1.4e-13 51.1 0.0 0.0057 16.8 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ02600.1 - 4.3e-10 39.8 1.2 0.0085 16.0 0.0 5.6 6 0 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.1 OAJ02600.1 - 1.9e-09 37.5 0.0 0.19 11.5 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 OAJ02600.1 - 3.4e-09 37.5 0.1 0.22 12.3 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.1 OAJ02600.1 - 1.4e-08 34.3 0.4 0.44 10.3 0.0 4.6 4 0 0 4 4 4 2 Part of AAA domain T2SE PF00437.15 OAJ02600.1 - 4.1e-07 29.1 0.0 0.027 13.3 0.0 3.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_18 PF13238.1 OAJ02600.1 - 1.4e-06 28.6 0.0 0.35 11.1 0.0 4.7 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 OAJ02600.1 - 8.4e-06 25.3 0.6 0.34 10.3 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 OAJ02600.1 - 1.5e-05 25.0 0.1 1.1 9.2 0.0 5.4 5 1 0 5 5 4 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 OAJ02600.1 - 3.1e-05 23.2 3.0 0.45 9.6 0.0 4.1 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAJ02600.1 - 4.1e-05 23.4 0.0 0.53 10.1 0.0 4.8 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.1 OAJ02600.1 - 0.0001 21.9 0.2 11 5.5 0.0 4.8 4 1 0 4 4 4 0 AAA domain AAA_29 PF13555.1 OAJ02600.1 - 0.0016 17.9 0.3 12 5.5 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ02600.1 - 0.0033 16.9 0.0 4.3 6.7 0.0 3.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family ABC_tran PF00005.22 OAJ02600.1 - 0.0035 17.6 0.2 51 4.1 0.0 4.7 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.1 OAJ02600.1 - 0.0049 16.3 2.3 1.2 8.4 0.0 4.0 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.17 OAJ02600.1 - 0.014 15.5 0.1 15 5.7 0.0 4.4 4 0 0 4 4 3 0 RNA helicase AAA_11 PF13086.1 OAJ02600.1 - 0.025 14.1 0.0 2.8 7.4 0.0 3.5 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 OAJ02600.1 - 0.061 13.1 0.0 2.9 7.6 0.0 3.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 OAJ02600.1 - 0.13 11.7 0.2 49 3.4 0.0 3.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NPV_P10 PF05531.7 OAJ02600.1 - 2.3 8.5 11.0 2.1 8.6 0.0 5.7 6 1 0 6 6 4 0 Nucleopolyhedrovirus P10 protein Sec1 PF00995.18 OAJ02601.1 - 3e-132 442.1 0.0 4.4e-132 441.6 0.0 1.2 1 0 0 1 1 1 1 Sec1 family Amidohydro_4 PF13147.1 OAJ02602.1 - 6.4e-11 42.8 1.0 1.3e-10 41.8 0.6 1.5 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_2 PF04909.9 OAJ02602.1 - 6.1e-06 26.0 0.3 1.5e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase zf-rbx1 PF12678.2 OAJ02603.1 - 1.9e-33 114.3 15.5 2.2e-33 114.1 10.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ02603.1 - 1.1e-17 63.6 11.9 1.4e-17 63.2 8.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 OAJ02603.1 - 5.7e-07 29.2 14.6 1.2e-06 28.2 8.5 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ02603.1 - 0.00012 21.7 9.5 0.00099 18.7 2.2 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ02603.1 - 0.00025 20.6 10.7 0.0028 17.2 7.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VSP PF03302.8 OAJ02603.1 - 0.0057 15.3 2.3 0.0061 15.2 1.6 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein zf-C3HC4_2 PF13923.1 OAJ02603.1 - 0.016 15.1 8.3 0.016 15.1 5.8 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ02603.1 - 0.21 11.3 11.5 1.4 8.6 7.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ02603.1 - 0.36 10.5 6.6 11 5.8 4.6 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 OAJ02603.1 - 1.1 9.3 12.3 2.6 8.0 8.5 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ02603.1 - 2.5 8.2 13.8 38 4.5 9.2 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 OAJ02603.1 - 3 7.8 16.8 0.23 11.4 6.8 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 OAJ02603.1 - 7.5 6.5 8.8 0.55 10.1 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FHA PF00498.21 OAJ02604.1 - 2.2e-14 53.3 0.0 4.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 OAJ02604.1 - 2.4e-08 33.6 14.2 3.6e-08 33.0 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ02604.1 - 7.5e-05 22.7 7.1 0.00014 21.9 4.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ02604.1 - 0.0058 16.4 5.6 0.0099 15.6 3.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 OAJ02604.1 - 0.011 15.3 13.2 0.018 14.7 9.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ02604.1 - 0.13 11.9 12.3 0.23 11.2 8.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ02604.1 - 0.2 11.7 15.1 0.31 11.0 10.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 OAJ02604.1 - 0.57 9.9 8.6 1 9.1 6.0 1.4 1 0 0 1 1 1 0 PHD-finger FAM176 PF14851.1 OAJ02604.1 - 9.9 5.8 6.7 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 FAM176 family Abhydrolase_5 PF12695.2 OAJ02605.1 - 1.1e-05 25.2 0.4 7.2e-05 22.5 0.0 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ02605.1 - 0.00021 21.2 1.1 0.00042 20.2 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.5 OAJ02605.1 - 0.006 15.5 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 OAJ02605.1 - 0.0075 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 OAJ02605.1 - 0.096 11.7 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ATP-synt_F PF01990.12 OAJ02606.1 - 3e-27 94.8 0.0 3.4e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit COPI_C PF06957.6 OAJ02607.1 - 6.7 5.1 7.9 12 4.3 5.5 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Complex1_LYR_1 PF13232.1 OAJ02608.1 - 3.4e-10 39.9 3.8 5.1e-10 39.4 2.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ02608.1 - 1.6e-09 37.3 7.2 2.9e-09 36.5 5.0 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 OAJ02608.1 - 0.0067 16.8 0.3 0.01 16.2 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like rve PF00665.21 OAJ02609.1 - 2e-20 73.1 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 OAJ02609.1 - 2.1e-07 30.4 0.1 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 OAJ02609.1 - 0.011 15.2 1.2 0.055 12.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.22 OAJ02610.1 - 2.2e-16 59.8 0.0 4.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ02610.1 - 7.5e-06 26.3 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 OAJ02610.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 OAJ02610.1 - 0.0017 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 OAJ02611.1 - 3.5e-11 43.0 0.9 2.9e-10 40.0 0.7 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ02611.1 - 3.6e-05 23.4 0.7 5.8e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Zinc knuckle adh_short PF00106.20 OAJ02613.1 - 0.0016 18.3 0.1 1.3 8.8 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase BAF1_ABF1 PF04684.8 OAJ02613.1 - 0.058 12.2 0.9 0.1 11.4 0.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MFS_1 PF07690.11 OAJ02614.1 - 7.7e-18 64.3 45.8 4.6e-17 61.7 30.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3689 PF12463.3 OAJ02615.1 - 0.39 9.4 1.4 0.82 8.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) ATP12 PF07542.6 OAJ02616.1 - 4.9e-35 120.1 0.0 7.9e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_hydro_88 PF07470.8 OAJ02617.1 - 1.3e-15 57.3 0.1 2.9e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 RCR PF12273.3 OAJ02617.1 - 1.6 9.3 9.6 15 6.1 0.4 3.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red 5TM-5TMR_LYT PF07694.7 OAJ02617.1 - 2.9 7.1 3.7 5.3 6.3 2.6 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT CBS PF00571.23 OAJ02618.1 - 1.2e-34 117.8 10.1 4.8e-09 35.8 0.0 4.9 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 OAJ02618.1 - 1.8e-06 27.5 0.1 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 PB1 domain NYN PF01936.13 OAJ02618.1 - 0.06 13.6 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 NYN domain DUF2413 PF10310.4 OAJ02620.1 - 6.6e-55 186.6 4.5 6.1e-53 180.2 3.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Hist_deacetyl PF00850.14 OAJ02621.1 - 4.5e-81 272.5 0.0 6.9e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ubiquitin PF00240.18 OAJ02622.1 - 7.2e-136 441.7 24.5 1.1e-33 114.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 OAJ02622.1 - 1.3e-77 255.4 22.7 5.6e-19 67.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ02622.1 - 5.3e-24 84.2 11.9 0.00016 21.8 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ02622.1 - 2.9e-21 75.8 1.6 0.0011 18.7 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 OAJ02622.1 - 5.6e-14 52.0 2.5 0.11 12.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 OAJ02622.1 - 8.9e-14 51.3 3.5 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 OAJ02622.1 - 1.3e-10 41.1 0.0 1.5 8.8 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 OAJ02622.1 - 2.1e-06 27.0 0.7 1.4 8.0 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 OAJ02622.1 - 4.6e-06 26.2 5.5 6.8 6.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain IGR PF09597.5 OAJ02622.1 - 1.4e-05 24.8 0.3 24 4.8 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif Big_3_3 PF13750.1 OAJ02622.1 - 2.4e-05 23.7 0.1 19 4.6 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 OAJ02622.1 - 3e-05 23.8 6.9 7.8 6.4 0.1 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 OAJ02622.1 - 0.0024 18.1 0.7 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain USP7_C2 PF14533.1 OAJ02622.1 - 0.0032 16.9 5.1 5.6 6.3 0.3 3.8 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 OAJ02622.1 - 0.0039 15.5 14.0 3.6 5.7 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 OAJ02622.1 - 0.0096 16.0 5.7 56 3.9 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Sortase PF04203.8 OAJ02622.1 - 0.021 14.4 2.5 37 3.9 0.0 3.9 2 1 2 4 4 4 0 Sortase family Tash_PEST PF07708.6 OAJ02622.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif CTDII PF01556.13 OAJ02622.1 - 0.038 13.8 16.6 6.6 6.7 0.3 4.5 1 1 3 4 4 4 0 DnaJ C terminal domain GABP-alpha PF11620.3 OAJ02622.1 - 0.05 13.5 7.8 47 4.0 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 OAJ02622.1 - 0.97 9.4 7.8 1.2e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 OAJ02622.1 - 1.1 9.4 14.8 57 3.8 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain eIF_4EBP PF05456.6 OAJ02623.1 - 2.1e-11 43.5 1.6 2.1e-11 43.5 1.1 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Methyltransf_PK PF05891.7 OAJ02627.1 - 4.5e-49 166.7 0.0 9.1e-16 57.8 0.0 4.2 4 0 0 4 4 4 4 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 OAJ02627.1 - 4e-05 23.4 0.0 0.00022 20.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ02627.1 - 0.0011 19.4 0.0 0.41 11.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ02627.1 - 0.0015 18.9 0.0 1.7 9.1 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain MRVI1 PF05781.7 OAJ02627.1 - 0.032 12.6 0.0 0.056 11.8 0.0 1.3 1 0 0 1 1 1 0 MRVI1 protein Methyltransf_25 PF13649.1 OAJ02627.1 - 0.1 12.9 0.0 5.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Med3 PF11593.3 OAJ02627.1 - 0.55 9.4 4.0 7.7 5.6 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal zf-C2H2 PF00096.21 OAJ02628.1 - 1.5e-07 31.3 9.1 0.0012 19.0 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ02628.1 - 3.6e-06 26.9 8.7 0.0065 16.7 1.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ02628.1 - 7.9e-06 25.9 3.3 7.9e-06 25.9 2.3 2.6 4 0 0 4 4 4 1 Zinc-finger double domain RVT_1 PF00078.22 OAJ02630.1 - 0.00032 20.1 0.0 0.0059 15.9 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BESS PF02944.15 OAJ02630.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 BESS motif FAM101 PF15068.1 OAJ02631.1 - 1.6 8.0 4.1 0.73 9.2 0.7 1.9 2 0 0 2 2 2 0 FAM101 family Myb_DNA-bind_6 PF13921.1 OAJ02633.1 - 3.5e-14 52.6 0.1 4.1e-05 23.5 0.0 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ02633.1 - 3.1e-12 46.3 2.8 0.00048 20.1 0.0 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain UBN2 PF14223.1 OAJ02634.1 - 4.9e-06 26.3 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ02634.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2_2 PF14227.1 OAJ02634.1 - 0.0046 16.4 0.1 0.0074 15.8 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TBP PF00352.16 OAJ02635.1 - 9.4e-69 226.8 0.2 1.7e-34 117.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 OAJ02635.1 - 0.0001 22.3 0.1 0.47 10.5 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) polyprenyl_synt PF00348.12 OAJ02635.1 - 0.11 11.3 0.2 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase Na_Ca_ex PF01699.19 OAJ02636.1 - 7.6e-18 64.4 25.0 1.5e-12 47.2 4.3 3.1 3 1 1 4 4 4 2 Sodium/calcium exchanger protein Aldo_ket_red PF00248.16 OAJ02637.1 - 4.1e-55 186.6 0.0 4.9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rhomboid PF01694.17 OAJ02638.1 - 6.7e-20 71.6 7.5 6.7e-20 71.6 5.2 1.6 2 0 0 2 2 2 1 Rhomboid family Pex14_N PF04695.8 OAJ02638.1 - 0.26 11.3 1.3 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HUN PF08729.5 OAJ02639.1 - 5.1e-08 32.6 0.0 5.1e-08 32.6 0.0 3.2 2 1 1 3 3 3 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 OAJ02639.1 - 0.0071 16.0 0.0 0.0071 16.0 0.0 3.9 4 0 0 4 4 4 2 Ubinuclein conserved middle domain Synaptobrevin PF00957.16 OAJ02640.1 - 8.2e-33 111.8 1.6 9.3e-33 111.6 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 OAJ02640.1 - 0.013 15.0 0.2 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF2976 PF11190.3 OAJ02640.1 - 0.099 12.1 1.8 0.09 12.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) MOZ_SAS PF01853.13 OAJ02641.1 - 2.9e-56 189.6 0.1 5.1e-56 188.9 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Lactonase PF10282.4 OAJ02642.1 - 2.5e-17 62.9 0.0 6.5e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Prenylcys_lyase PF07156.9 OAJ02643.1 - 1.1e-38 133.1 0.0 5.1e-20 71.6 0.0 3.1 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 OAJ02643.1 - 3.5e-11 42.9 0.0 1.1e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ02643.1 - 1.7e-06 27.1 0.3 2.7e-06 26.5 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ02643.1 - 1.7e-05 24.6 0.1 0.00056 19.7 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ02643.1 - 0.00013 21.9 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ02643.1 - 0.0012 18.0 0.1 0.002 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAJ02643.1 - 0.0021 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 OAJ02643.1 - 0.0042 15.9 0.6 0.016 14.1 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 OAJ02643.1 - 0.0048 15.5 0.1 0.0073 14.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 OAJ02643.1 - 0.0062 15.6 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 OAJ02643.1 - 0.007 14.8 0.0 0.01 14.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 OAJ02643.1 - 0.028 13.2 0.3 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 OAJ02643.1 - 0.036 14.4 0.1 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ02643.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 OAJ02643.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TAFII28 PF04719.9 OAJ02643.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Use1 PF09753.4 OAJ02644.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 E1_DerP2_DerF2 PF02221.10 OAJ02645.1 - 5.5e-27 94.6 0.0 7e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 OAJ02645.1 - 0.0017 18.3 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Galactosyl_T PF01762.16 OAJ02646.1 - 1.3e-09 37.9 0.4 7.4e-05 22.4 0.0 3.2 2 1 1 3 3 3 3 Galactosyltransferase EF-hand_1 PF00036.27 OAJ02647.1 - 1.9e-25 86.1 7.5 3.2e-08 32.3 0.0 4.9 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 OAJ02647.1 - 4.6e-23 81.1 9.6 1.2e-11 44.5 1.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 OAJ02647.1 - 3.4e-22 76.2 1.3 3.3e-06 26.5 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ02647.1 - 7.9e-13 47.8 7.0 0.00035 20.1 0.2 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 OAJ02647.1 - 9e-11 40.6 13.8 4.8e-05 22.5 0.0 4.6 5 1 0 5 5 5 3 EF hand EF-hand_4 PF12763.2 OAJ02647.1 - 7.5e-10 38.4 6.5 0.00077 19.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ02647.1 - 1.6e-05 24.7 0.7 0.00086 19.1 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain Mad3_BUB1_II PF08171.6 OAJ02647.1 - 0.0073 16.1 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 SPARC_Ca_bdg PF10591.4 OAJ02647.1 - 0.035 14.1 2.3 1.4 8.9 0.1 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 OAJ02647.1 - 0.05 13.6 0.1 1.6 8.8 0.0 2.6 3 1 0 3 3 3 0 EF hand S10_plectin PF03501.10 OAJ02647.1 - 0.059 13.2 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Plectin/S10 domain Abhydrolase_6 PF12697.2 OAJ02648.1 - 5.5e-13 49.3 0.5 1.2e-12 48.2 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ02648.1 - 0.001 18.8 0.0 0.0064 16.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ02648.1 - 0.0015 18.1 0.1 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold YTH PF04146.10 OAJ02649.1 - 2.4e-42 143.8 0.0 1.7e-41 141.0 0.0 2.3 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 OAJ02649.1 - 0.0015 18.1 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02649.1 - 0.02 14.7 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF726 PF05277.7 OAJ02650.1 - 1e-37 129.8 8.4 3.5e-28 98.4 2.9 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 OAJ02650.1 - 0.00094 19.1 0.5 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ02650.1 - 0.0037 17.0 0.1 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 OAJ02650.1 - 0.06 11.7 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 DUF46 PF01864.12 OAJ02650.1 - 6 6.7 8.3 34 4.2 2.4 2.5 2 0 0 2 2 2 0 Putative integral membrane protein DUF46 CoA_transf_3 PF02515.12 OAJ02651.1 - 2.5e-67 225.8 0.2 1.2e-66 223.6 0.1 1.9 2 0 0 2 2 2 1 CoA-transferase family III DHH PF01368.15 OAJ02652.1 - 0.0019 17.8 0.0 0.0078 15.8 0.0 1.9 1 1 0 1 1 1 1 DHH family zf-C2H2 PF00096.21 OAJ02653.1 - 3.3e-08 33.4 12.4 0.00081 19.5 1.3 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ02653.1 - 4.4e-06 26.7 3.7 4.4e-06 26.7 2.6 4.2 4 0 0 4 4 4 3 Zinc-finger double domain CitT PF12431.3 OAJ02653.1 - 0.035 14.1 0.2 0.95 9.6 0.0 3.3 3 0 0 3 3 3 0 Transcriptional regulator DUF221 PF02714.10 OAJ02654.1 - 4.5e-40 137.4 11.3 6.3e-40 137.0 7.8 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 Pox_P21 PF05313.7 OAJ02654.1 - 1.4 8.1 4.1 2.3 7.4 2.9 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein PIF1 PF05970.9 OAJ02659.1 - 3e-60 204.0 1.0 8.9e-58 195.9 0.7 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ02659.1 - 1.7e-16 60.4 0.0 2.8e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ02659.1 - 8.5e-07 29.1 0.0 1.8e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 OAJ02659.1 - 0.00019 21.4 0.0 0.0072 16.4 0.0 2.9 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 OAJ02659.1 - 0.00051 19.6 0.2 0.56 9.6 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 OAJ02659.1 - 0.00098 18.1 0.1 0.0016 17.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 OAJ02659.1 - 0.0018 18.2 0.3 0.0058 16.6 0.0 1.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_19 PF13245.1 OAJ02659.1 - 0.0026 17.4 0.4 0.0064 16.2 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 OAJ02659.1 - 0.0042 15.7 0.0 0.0079 14.8 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 OAJ02659.1 - 0.0044 16.0 0.0 0.0088 15.0 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 OAJ02659.1 - 0.0054 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 OAJ02659.1 - 0.0055 15.9 0.1 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 OAJ02659.1 - 0.016 14.6 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Herpes_Helicase PF02689.9 OAJ02659.1 - 0.018 12.8 0.1 0.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Helicase Arch_ATPase PF01637.13 OAJ02659.1 - 0.018 14.7 0.0 0.059 13.0 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 OAJ02659.1 - 0.026 14.4 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ02659.1 - 0.026 13.9 0.2 0.27 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain HTH_17 PF12728.2 OAJ02659.1 - 0.03 14.5 0.1 7.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain AAA_11 PF13086.1 OAJ02659.1 - 0.032 13.8 0.1 2.1 7.8 0.0 2.5 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 OAJ02659.1 - 0.038 13.6 0.1 0.096 12.3 0.0 1.8 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 OAJ02659.1 - 0.093 12.4 0.2 0.81 9.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 OAJ02659.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 OAJ02659.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_7 PF12775.2 OAJ02659.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 AAA_32 PF13654.1 OAJ02659.1 - 0.15 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain RHH_1 PF01402.16 OAJ02659.1 - 0.29 11.1 1.5 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family NAD_kinase PF01513.16 OAJ02660.1 - 2.7e-52 177.3 0.0 3.2e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase HAD PF12710.2 OAJ02661.1 - 1.4e-27 97.1 0.0 3e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ02661.1 - 2.8e-25 88.7 0.1 2.1e-24 85.8 0.1 2.2 1 1 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.3 OAJ02661.1 - 1.5e-24 86.1 0.0 3.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.21 OAJ02661.1 - 5.5e-22 79.2 0.0 3.9e-20 73.1 0.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 OAJ02661.1 - 7.2e-05 22.3 9.2 7.2e-05 22.3 6.4 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 OAJ02661.1 - 9e-05 22.3 0.1 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ02661.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ02661.1 - 0.064 12.8 0.0 0.26 10.8 0.0 2.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase UCH PF00443.24 OAJ02662.1 - 6e-70 235.4 0.0 9.2e-70 234.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ02662.1 - 9.6e-24 84.3 0.0 1.7e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 OAJ02662.1 - 4.1e-09 36.4 0.9 1e-08 35.1 0.6 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.15 OAJ02662.1 - 0.00012 22.4 0.0 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain MIT PF04212.13 OAJ02662.1 - 0.051 13.4 0.7 0.099 12.5 0.5 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF104 PF01954.11 OAJ02662.1 - 0.19 11.7 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 PTPLA PF04387.9 OAJ02663.1 - 1.7e-50 170.6 5.7 3.1e-50 169.8 3.9 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA PGAP1 PF07819.8 OAJ02664.1 - 5.7e-59 199.4 0.0 8.6e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 OAJ02664.1 - 0.0067 15.7 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Histone PF00125.19 OAJ02665.1 - 7.6e-30 102.8 0.1 2.4e-29 101.2 0.0 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ02665.1 - 0.044 13.9 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF3305 PF11749.3 OAJ02665.1 - 0.045 13.6 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3305) Rhomboid_SP PF12595.3 OAJ02665.1 - 0.19 11.2 4.0 0.27 10.8 2.7 1.2 1 0 0 1 1 1 0 Rhomboid serine protease tRNA-synt_1e PF01406.14 OAJ02667.1 - 2.4e-120 401.2 0.0 1e-71 241.5 0.1 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 OAJ02667.1 - 1.1e-07 30.9 1.0 4e-05 22.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 OAJ02667.1 - 4.2e-05 21.7 0.1 0.0013 16.8 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 OAJ02667.1 - 0.00034 20.8 0.0 0.00034 20.8 0.0 2.9 3 0 0 3 3 3 1 DALR domain tRNA-synt_1c PF00749.16 OAJ02667.1 - 0.0023 16.6 0.2 0.43 9.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 OAJ02667.1 - 0.019 13.6 0.0 1.7 7.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF3991 PF13154.1 OAJ02667.1 - 0.076 13.2 0.3 0.68 10.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3991) SPT6_acidic PF14632.1 OAJ02668.1 - 7.5 6.7 14.9 6.8 6.9 0.4 2.5 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Transposase_21 PF02992.9 OAJ02669.1 - 5.2e-19 68.2 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02669.1 - 0.00011 21.6 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ATP_Ca_trans_C PF12424.3 OAJ02670.1 - 0.001 19.3 2.7 0.0022 18.3 1.2 2.1 1 1 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal DUF3328 PF11807.3 OAJ02670.1 - 0.11 12.1 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) FANCI_S4 PF14678.1 OAJ02671.1 - 0.014 14.5 1.0 0.02 14.0 0.7 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 TrbC PF04956.8 OAJ02671.1 - 0.7 9.9 4.7 1.1 9.3 0.4 2.9 2 1 1 3 3 3 0 TrbC/VIRB2 family DUF720 PF05302.6 OAJ02671.1 - 1.4 8.6 8.0 1.3 8.7 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF720) DUF3814 PF12769.2 OAJ02671.1 - 4.3 7.5 6.2 1.2 9.3 1.2 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3814) Phage_holin_1 PF04531.8 OAJ02671.1 - 7.1 6.7 11.2 2.2 8.4 0.0 2.8 3 1 0 3 3 3 0 Bacteriophage holin Bestrophin PF01062.16 OAJ02672.1 - 1e-38 132.9 2.0 8.6e-38 129.9 1.4 1.9 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FANCI_S4 PF14678.1 OAJ02673.1 - 0.073 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 BCDHK_Adom3 PF10436.4 OAJ02674.1 - 6.4e-62 207.8 0.0 9.8e-62 207.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ02674.1 - 4.4e-19 68.2 0.0 7.4e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ02674.1 - 3.3e-06 26.8 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L18e PF00828.14 OAJ02675.1 - 4.2e-21 75.6 0.0 6.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 BNR PF02012.15 OAJ02677.1 - 0.00013 21.2 22.3 1.3 9.1 1.4 6.6 6 0 0 6 6 6 4 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 OAJ02677.1 - 0.014 15.1 0.1 2.9 7.7 0.0 2.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain F5_F8_type_C PF00754.20 OAJ02677.1 - 0.043 13.6 2.5 3.9 7.3 0.0 4.3 6 0 0 6 6 6 0 F5/8 type C domain CoA_transf_3 PF02515.12 OAJ02678.1 - 9.3e-43 145.6 0.0 1.4e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Sec1 PF00995.18 OAJ02679.1 - 1.2e-94 317.9 0.0 2.3e-94 317.0 0.0 1.5 1 1 0 1 1 1 1 Sec1 family XisH PF08814.5 OAJ02679.1 - 0.37 10.7 0.0 0.69 9.9 0.0 1.3 1 0 0 1 1 1 0 XisH protein SNF2_N PF00176.18 OAJ02680.1 - 1.7e-81 273.3 0.3 3.7e-81 272.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 OAJ02680.1 - 3.6e-39 133.1 0.2 3.6e-39 133.1 0.2 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 OAJ02680.1 - 1.5e-29 102.6 5.6 1.5e-29 102.6 3.8 3.1 4 0 0 4 4 3 1 HAND Helicase_C PF00271.26 OAJ02680.1 - 7.3e-15 54.5 0.0 1.7e-13 50.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02680.1 - 4.5e-08 33.1 0.0 4.5e-08 33.1 0.0 3.3 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ02680.1 - 9.7e-08 31.6 0.3 4.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HWE_HK PF07536.9 OAJ02680.1 - 0.001 19.4 0.9 0.16 12.3 0.0 3.1 2 0 0 2 2 2 1 HWE histidine kinase Myb_DNA-binding PF00249.26 OAJ02680.1 - 0.0032 17.4 0.0 0.058 13.4 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 OAJ02680.1 - 0.0056 16.1 0.2 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 OAJ02680.1 - 0.011 15.6 0.2 0.051 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAJ02680.1 - 0.097 12.8 1.6 0.27 11.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain Aldedh PF00171.17 OAJ02681.1 - 2.5e-130 434.9 0.4 2.8e-130 434.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 OAJ02681.1 - 0.001 17.8 0.9 0.01 14.5 0.6 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Telomere_reg-2 PF10193.4 OAJ02682.1 - 1.5e-25 89.6 0.0 4.4e-25 88.1 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Mito_carr PF00153.22 OAJ02683.1 - 7.9e-58 192.1 1.2 1.2e-17 63.3 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein CBFD_NFYB_HMF PF00808.18 OAJ02684.1 - 2.9e-20 72.0 0.0 5.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ02684.1 - 7.5e-06 25.9 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MCM PF00493.18 OAJ02685.1 - 5.3e-143 475.7 0.2 6.7e-143 475.4 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ02685.1 - 1.4e-16 61.0 0.0 3.9e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ02685.1 - 1.8e-06 27.2 0.0 0.00043 19.5 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 OAJ02685.1 - 8.6e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 OAJ02685.1 - 0.00017 21.2 0.0 0.0022 17.5 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ02685.1 - 0.024 14.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 OAJ02685.1 - 0.045 14.1 0.4 0.16 12.3 0.2 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 OAJ02685.1 - 0.11 12.6 0.3 0.59 10.3 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L28e PF01778.12 OAJ02686.1 - 3.2e-27 95.2 0.1 5.5e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Citrate_ly_lig PF08218.6 OAJ02686.1 - 0.041 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain DUF2084 PF09857.4 OAJ02686.1 - 0.11 12.1 0.2 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2084) Prefoldin PF02996.12 OAJ02687.1 - 3.8e-29 100.7 0.0 4.8e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.6 OAJ02687.1 - 0.011 16.1 1.4 0.39 11.1 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Cortex-I_coil PF09304.5 OAJ02687.1 - 0.068 13.2 3.8 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil SOR_SNZ PF01680.12 OAJ02690.1 - 4.8e-115 382.3 5.7 7.4e-115 381.7 4.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 OAJ02690.1 - 1.1e-06 27.9 8.2 4e-05 22.8 0.5 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 OAJ02690.1 - 0.0027 16.6 0.7 1 8.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 OAJ02690.1 - 0.03 13.4 4.5 0.086 11.9 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 OAJ02690.1 - 0.037 13.2 0.1 0.65 9.2 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.16 OAJ02690.1 - 0.1 11.6 0.2 0.82 8.6 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF726 PF05277.7 OAJ02691.1 - 2.3e-117 391.7 2.9 3e-117 391.3 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 OAJ02691.1 - 0.0019 17.9 0.6 0.0053 16.5 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 OAJ02692.1 - 6.9e-22 77.8 0.0 8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family mRNA_cap_enzyme PF01331.14 OAJ02693.1 - 4e-47 160.4 0.1 5.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 OAJ02693.1 - 8.7e-16 58.1 0.1 1.1e-08 35.3 0.1 2.3 2 0 0 2 2 2 2 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 OAJ02693.1 - 5.8e-08 32.3 0.0 1.3e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Flu_PB1 PF00602.12 OAJ02693.1 - 0.067 10.9 0.2 0.094 10.4 0.1 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 IPK PF03770.11 OAJ02694.1 - 3.1e-52 177.1 0.0 5.3e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase E1-E2_ATPase PF00122.15 OAJ02695.1 - 4.4e-60 202.5 0.4 1.9e-59 200.4 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ02695.1 - 8.7e-24 85.1 0.4 1.7e-23 84.1 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ02695.1 - 4.7e-12 46.4 0.1 1.2e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ02695.1 - 1.4e-10 40.4 0.2 4.1e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ02695.1 - 4.8e-05 23.0 0.3 0.00011 21.8 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ02695.1 - 0.0085 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit PGM_PMM_I PF02878.11 OAJ02696.1 - 7.5e-37 125.8 0.0 1.1e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 OAJ02696.1 - 8.9e-28 96.5 0.0 2.2e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 OAJ02696.1 - 1.3e-13 51.1 0.0 3.4e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ02696.1 - 3.3e-09 36.6 0.0 1.1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RVT_1 PF00078.22 OAJ02697.1 - 1.8e-23 83.0 0.0 6.4e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) NPR3 PF03666.8 OAJ02698.1 - 7.1e-37 127.0 0.0 9.8e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Flagellar_rod PF05149.7 OAJ02698.1 - 0.031 13.4 0.2 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Bd3614_N PF14442.1 OAJ02699.1 - 7.5 6.5 14.3 2.8 7.9 1.6 2.5 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal PBP1_TM PF14812.1 OAJ02699.1 - 7.6 6.9 11.0 3.3 8.0 2.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 OAJ02699.1 - 8.6 6.5 10.1 7.6 6.7 2.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WD40 PF00400.27 OAJ02700.1 - 2.9e-05 23.7 2.8 0.00015 21.5 0.1 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2781 PF10914.3 OAJ02701.1 - 6e-30 104.0 7.4 6.9e-30 103.8 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.13 OAJ02702.1 - 1.3e-06 28.2 10.6 1.3e-06 28.2 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.11 OAJ02704.1 - 4.1e-17 62.2 0.0 3.2e-11 43.2 0.1 2.0 2 0 0 2 2 2 2 RNA polymerase Rpb4 Hydrolase PF00702.21 OAJ02705.1 - 2.9e-19 70.3 0.1 4.1e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ02705.1 - 5.4e-08 33.2 0.0 6.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4451 PF14616.1 OAJ02706.1 - 3.1e-25 88.3 1.1 7.1e-25 87.1 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) Chitin_synth_1 PF01644.12 OAJ02707.1 - 2.2e-86 287.7 0.1 5.7e-86 286.3 0.0 1.7 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ02707.1 - 1e-27 95.6 0.0 2.1e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ02707.1 - 2.4e-22 79.0 4.4 6e-17 61.2 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ02707.1 - 6.2e-07 29.3 5.8 2.8e-06 27.1 4.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ02707.1 - 2.1e-05 24.4 0.0 5.3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 OAJ02708.1 - 8.6e-62 208.6 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02708.1 - 3.3e-38 131.2 0.0 4.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02708.1 - 3.5e-06 26.1 0.0 6.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ADH_N PF08240.7 OAJ02709.1 - 1.4e-28 98.8 2.3 3.4e-28 97.5 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ02709.1 - 5.5e-22 77.6 0.1 8.8e-22 77.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MobB PF03205.9 OAJ02709.1 - 0.077 12.7 0.1 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma70_r1_2 PF00140.15 OAJ02715.1 - 0.56 9.9 2.8 0.97 9.1 1.9 1.4 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Retrotrans_gag PF03732.12 OAJ02716.1 - 3e-11 43.2 0.4 3.6e-10 39.7 0.3 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ02716.1 - 0.00017 21.3 1.0 0.00027 20.7 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle rve PF00665.21 OAJ02718.1 - 1.9e-21 76.3 0.0 4.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ02718.1 - 8e-16 58.0 0.1 2.2e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 OAJ02718.1 - 2.2e-07 30.8 0.0 1.8e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ02718.1 - 7.9e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease rve_3 PF13683.1 OAJ02718.1 - 0.027 13.9 0.0 0.11 12.0 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain UPF0184 PF03670.8 OAJ02718.1 - 0.056 13.6 0.1 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Caudal_act PF04731.7 OAJ02718.1 - 0.075 13.3 1.2 0.25 11.6 0.8 1.9 1 0 0 1 1 1 0 Caudal like protein activation region MKT1_C PF12246.3 OAJ02720.1 - 7.6e-63 211.7 0.0 1.9e-62 210.4 0.0 1.6 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 OAJ02720.1 - 1.3e-21 76.7 0.0 2.6e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 OAJ02720.1 - 3.8e-07 30.0 0.0 7.5e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAJ02720.1 - 2.7e-06 27.5 0.0 6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DHH PF01368.15 OAJ02721.1 - 5.8e-08 32.4 0.2 7.9e-07 28.8 0.0 2.7 2 2 0 2 2 2 1 DHH family DHHA2 PF02833.9 OAJ02721.1 - 3.4e-05 24.0 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 DHHA2 domain Sugar_tr PF00083.19 OAJ02722.1 - 2.2e-87 293.5 23.2 2.8e-87 293.2 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ02722.1 - 2.6e-13 49.4 42.2 5.4e-12 45.0 11.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DHO_dh PF01180.16 OAJ02723.1 - 2.6e-91 305.6 0.0 1.7e-90 302.9 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Proteasome PF00227.21 OAJ02724.1 - 5.6e-46 156.2 0.3 5.3e-43 146.5 0.1 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 OAJ02724.1 - 3.5e-14 51.8 0.1 6.3e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Methyltransf_15 PF09445.5 OAJ02725.1 - 4.7e-35 120.5 0.0 3.5e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 OAJ02725.1 - 8e-11 42.0 0.0 2.3e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ02725.1 - 1.8e-08 34.2 0.0 8.1e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.2 OAJ02725.1 - 1.1e-07 32.3 0.2 1.1e-07 32.3 0.1 2.4 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ02725.1 - 7.7e-06 25.5 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 OAJ02725.1 - 5.3e-05 22.8 0.0 0.00014 21.4 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 OAJ02725.1 - 9.4e-05 21.5 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Cons_hypoth95 PF03602.10 OAJ02725.1 - 0.00018 20.9 0.9 0.011 15.1 0.0 2.6 2 1 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 OAJ02725.1 - 0.00055 20.2 0.0 0.0018 18.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 OAJ02725.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Spt5_N PF11942.3 OAJ02725.1 - 0.015 15.9 9.2 0.015 15.9 6.4 4.1 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal tRNA_U5-meth_tr PF05958.6 OAJ02725.1 - 0.029 13.0 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.11 OAJ02725.1 - 0.046 12.6 0.0 0.075 11.9 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Pkinase PF00069.20 OAJ02726.1 - 1e-33 116.6 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02726.1 - 5e-12 45.4 0.0 7.2e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Zip PF02535.17 OAJ02726.1 - 0.037 13.0 1.3 0.058 12.3 0.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1777 PF08648.7 OAJ02726.1 - 3.1 7.4 21.1 0.034 13.8 9.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Zn_clus PF00172.13 OAJ02728.1 - 6.8e-07 29.0 11.0 6.8e-07 29.0 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Drf_GBD PF06371.8 OAJ02729.1 - 8.2e-13 48.1 0.0 2.1e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain ATP-synt_DE_N PF02823.11 OAJ02730.1 - 4.7e-20 71.1 0.0 6.8e-20 70.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cas_Csa5 PF09702.5 OAJ02730.1 - 0.067 13.2 0.2 0.39 10.8 0.1 2.1 2 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DBR1 PF05011.8 OAJ02731.1 - 1.6e-15 57.2 0.0 3.6e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 OAJ02731.1 - 3.3e-05 23.3 1.2 5.2e-05 22.7 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CytochromB561_N PF09786.4 OAJ02731.1 - 0.15 10.5 0.3 0.21 9.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mito_carr PF00153.22 OAJ02732.1 - 0.029 14.0 0.5 2.2 8.0 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial carrier protein Zn_clus PF00172.13 OAJ02733.1 - 3.1e-05 23.7 8.3 5.5e-05 22.9 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PITH PF06201.8 OAJ02735.1 - 6.5e-28 97.4 0.0 2.9e-26 92.0 0.0 2.2 1 1 0 1 1 1 1 PITH domain DDE_3 PF13358.1 OAJ02736.1 - 1.8e-28 99.1 0.0 3.3e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ02736.1 - 3.8e-05 24.4 2.0 0.00012 22.8 1.1 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 OAJ02736.1 - 0.00012 21.5 0.3 0.00045 19.7 0.1 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.1 OAJ02736.1 - 0.0008 19.5 0.3 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ02736.1 - 0.00098 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.6 OAJ02736.1 - 0.023 13.4 0.1 0.24 10.1 0.0 2.0 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain DUF3123 PF11321.3 OAJ02736.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF3486 PF11985.3 OAJ02736.1 - 0.12 12.4 0.4 0.21 11.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3486) HTH_7 PF02796.10 OAJ02736.1 - 0.13 12.1 1.3 2.3 8.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase YdjO PF14169.1 OAJ02736.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cold-inducible protein YdjO 2OG-FeII_Oxy_2 PF13532.1 OAJ02739.1 - 7.4e-14 52.0 0.0 2.3e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ02739.1 - 0.0068 16.6 0.0 0.047 13.9 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PB1 PF00564.19 OAJ02740.1 - 3.5e-05 23.3 0.0 3.5e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 PB1 domain Ebola_NP PF05505.7 OAJ02740.1 - 0.92 7.4 7.0 1.7 6.6 4.9 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Ribosomal_L37 PF08561.5 OAJ02746.1 - 1.7e-24 85.1 2.4 5.5e-23 80.3 1.7 2.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF3520 PF12034.3 OAJ02746.1 - 6.5 6.8 11.7 0.39 10.8 4.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) FGGY_C PF02782.11 OAJ02747.1 - 0.0032 17.1 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Transposase_21 PF02992.9 OAJ02748.1 - 6.9e-22 77.6 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Isy1 PF06246.7 OAJ02749.1 - 1.8e-72 243.8 5.3 2.1e-72 243.6 2.0 1.7 1 1 1 2 2 2 1 Isy1-like splicing family Ribosomal_L30 PF00327.15 OAJ02750.1 - 1.4e-09 37.3 0.1 2.1e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Mak10 PF04112.8 OAJ02751.1 - 9e-40 135.6 0.0 1.7e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF4416 PF14385.1 OAJ02751.1 - 0.008 15.9 0.2 0.02 14.6 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4416) phage_tail_N PF08400.5 OAJ02753.1 - 7.2 6.3 7.5 0.15 11.7 0.4 1.7 2 0 0 2 2 2 0 Prophage tail fibre N-terminal AAA_11 PF13086.1 OAJ02755.1 - 1.1e-50 172.3 7.6 2e-46 158.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_12 PF13087.1 OAJ02755.1 - 3e-49 167.1 0.0 6.5e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ02755.1 - 8.2e-13 47.9 2.9 3.4e-12 45.9 0.1 3.0 3 0 0 3 3 3 1 Part of AAA domain UvrD-helicase PF00580.16 OAJ02755.1 - 0.00012 21.5 0.0 0.47 9.7 0.0 2.6 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 OAJ02755.1 - 0.00022 20.7 0.0 0.011 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 OAJ02755.1 - 0.00023 20.7 0.0 0.59 9.6 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 OAJ02755.1 - 0.0011 19.0 0.0 0.0049 16.9 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAJ02755.1 - 0.0056 16.8 0.0 0.027 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ02755.1 - 0.0056 16.8 0.7 0.024 14.8 0.3 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ02755.1 - 0.0063 16.5 1.4 0.026 14.4 0.0 2.8 3 1 0 3 3 2 1 AAA ATPase domain UvrD_C PF13361.1 OAJ02755.1 - 0.022 14.2 0.7 0.4 10.0 0.0 2.6 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_23 PF13476.1 OAJ02755.1 - 0.049 13.9 6.7 0.46 10.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain Chitin_synth_1 PF01644.12 OAJ02756.1 - 6.1e-87 289.5 0.1 9e-87 288.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 OAJ02756.1 - 8.1e-32 108.7 0.2 1.5e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 OAJ02756.1 - 1.5e-24 86.2 5.9 6.6e-23 80.8 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ02756.1 - 1.5e-08 34.6 0.6 1.5e-08 34.6 0.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ02756.1 - 0.0099 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Peptidase_S8 PF00082.17 OAJ02757.1 - 4.8e-43 147.3 1.5 9e-43 146.4 1.1 1.4 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.3 OAJ02757.1 - 8.9e-40 136.0 0.0 1.4e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II MBA1 PF07961.6 OAJ02757.1 - 1.5 7.6 3.5 0.37 9.6 0.1 1.6 2 0 0 2 2 2 0 MBA1-like protein ABC_membrane PF00664.18 OAJ02758.1 - 4e-97 324.9 25.3 9.5e-51 172.8 8.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ02758.1 - 3.8e-68 228.0 2.1 3.3e-33 114.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_ATPase PF09818.4 OAJ02758.1 - 4.9e-15 55.0 0.8 8.3e-05 21.3 0.1 4.3 4 0 0 4 4 4 3 Predicted ATPase of the ABC class SMC_N PF02463.14 OAJ02758.1 - 3.7e-14 52.4 11.7 7.6e-05 22.0 0.0 4.7 3 2 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ02758.1 - 4e-14 53.2 0.0 0.02 14.8 0.0 4.3 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 OAJ02758.1 - 1.2e-08 34.3 0.7 0.00032 20.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ02758.1 - 4.5e-08 33.2 0.9 0.011 15.7 0.0 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 OAJ02758.1 - 3.8e-07 30.9 0.0 0.038 14.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ02758.1 - 9.4e-07 29.0 0.6 0.14 12.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 OAJ02758.1 - 2.2e-06 26.9 0.0 0.062 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ02758.1 - 3.5e-06 27.4 3.3 0.35 11.1 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 OAJ02758.1 - 5.3e-06 25.9 0.0 0.041 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 OAJ02758.1 - 0.00016 21.3 1.1 1.1 8.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 OAJ02758.1 - 0.00016 21.8 0.2 0.72 10.0 0.0 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 OAJ02758.1 - 0.00022 21.0 7.5 0.085 12.7 0.2 3.9 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 OAJ02758.1 - 0.00023 21.4 0.0 0.83 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ02758.1 - 0.00038 20.3 0.0 2.4 8.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.9 OAJ02758.1 - 0.0004 20.1 0.1 2.8 7.6 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAJ02758.1 - 0.0033 17.1 1.4 0.49 10.1 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain DUF87 PF01935.12 OAJ02758.1 - 0.0088 15.8 3.0 2.1 8.1 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function DUF87 PRK PF00485.13 OAJ02758.1 - 0.0094 15.5 0.0 2.2 7.7 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 OAJ02758.1 - 0.011 15.8 0.0 5.7 7.1 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_33 PF13671.1 OAJ02758.1 - 0.011 15.5 2.5 1.1 9.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 OAJ02758.1 - 0.012 15.5 3.4 4.8 7.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 OAJ02758.1 - 0.017 14.1 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 OAJ02758.1 - 0.02 15.4 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ02758.1 - 0.023 14.1 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 OAJ02758.1 - 0.027 13.1 3.6 0.82 8.2 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit Viral_helicase1 PF01443.13 OAJ02758.1 - 0.031 13.7 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 OAJ02758.1 - 0.042 13.4 0.1 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 OAJ02758.1 - 0.044 13.4 0.1 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 OAJ02758.1 - 0.066 12.6 2.5 6.9 6.0 0.2 3.4 3 1 1 4 4 4 0 AAA-like domain Rad17 PF03215.10 OAJ02758.1 - 0.09 11.4 0.0 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 OAJ02758.1 - 0.11 11.3 0.1 11 4.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 OAJ02758.1 - 0.14 11.8 0.3 21 4.6 0.1 2.8 2 0 0 2 2 2 0 NACHT domain MAP65_ASE1 PF03999.7 OAJ02758.1 - 1.9 7.0 11.4 2.9 6.3 7.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.20 OAJ02759.1 - 1.8e-40 138.7 0.0 1.1e-25 90.2 0.0 4.3 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02759.1 - 1.6e-21 76.5 0.0 2.7e-18 65.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 OAJ02759.1 - 0.00079 19.2 0.1 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ02759.1 - 0.025 13.5 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Ion_trans_2 PF07885.11 OAJ02760.1 - 7.4e-32 108.9 31.4 3.1e-16 58.8 7.0 2.4 2 0 0 2 2 2 2 Ion channel Lig_chan PF00060.21 OAJ02760.1 - 1 9.0 9.0 0.86 9.3 0.3 2.8 2 1 0 2 2 2 0 Ligand-gated ion channel Proteasome PF00227.21 OAJ02761.1 - 5e-38 130.2 0.0 5.7e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Dynamin_N PF00350.18 OAJ02762.1 - 4.9e-16 58.9 0.0 9.2e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 OAJ02762.1 - 5.6e-10 39.2 0.0 2.1e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ02762.1 - 1.3e-08 34.4 0.3 2.7e-07 30.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ02762.1 - 2.7e-05 24.6 0.1 0.048 14.1 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein IIGP PF05049.8 OAJ02762.1 - 0.0023 16.8 0.3 0.037 12.8 0.0 2.4 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 OAJ02762.1 - 0.009 15.5 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain PglZ PF08665.7 OAJ02762.1 - 0.048 13.3 0.2 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 PglZ domain PduV-EutP PF10662.4 OAJ02762.1 - 0.09 12.2 0.2 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 OAJ02762.1 - 0.13 11.5 1.0 6.4 5.9 0.0 2.9 2 1 1 3 3 3 0 ADP-ribosylation factor family IncA PF04156.9 OAJ02762.1 - 0.14 11.7 8.5 0.23 11.0 3.8 2.5 2 1 0 2 2 2 0 IncA protein GTPase_Cys_C PF12631.2 OAJ02762.1 - 0.5 10.8 3.1 1.1 9.7 0.3 3.0 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Fungal_trans PF04082.13 OAJ02764.1 - 3.5e-07 29.3 0.1 6.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HA2 PF04408.18 OAJ02765.1 - 1e-14 54.3 0.0 2.9e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ02765.1 - 4.8e-14 51.9 0.1 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ02765.1 - 2.7e-10 39.9 0.0 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ02765.1 - 4.1e-05 23.7 0.1 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 OAJ02765.1 - 0.045 12.8 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC OB_NTP_bind PF07717.11 OAJ02765.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 OAJ02765.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF494 PF04361.8 OAJ02765.1 - 0.23 11.1 0.0 0.48 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) IMS PF00817.15 OAJ02766.1 - 3.6e-38 130.6 0.0 7.5e-38 129.6 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ02766.1 - 2.3e-12 46.9 0.0 4.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 OAJ02766.1 - 0.00014 21.7 0.6 0.13 12.1 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) UDPG_MGDP_dh_N PF03721.9 OAJ02774.1 - 9.2e-60 201.1 0.0 1.7e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 OAJ02774.1 - 2.2e-34 117.7 0.0 1.5e-32 111.8 0.0 2.8 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 OAJ02774.1 - 8.7e-32 109.2 0.0 1.6e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 OAJ02774.1 - 0.00018 21.3 0.2 0.032 13.9 0.0 2.6 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ02774.1 - 0.0032 17.8 0.1 5.5 7.4 0.1 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent RRP7 PF12923.2 OAJ02776.1 - 0.18 11.8 0.4 0.29 11.1 0.2 1.2 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DUF1264 PF06884.6 OAJ02777.1 - 4.3e-44 149.9 0.0 7e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) GET2 PF08690.5 OAJ02778.1 - 2 7.6 3.4 6.5 5.9 0.2 2.6 2 0 0 2 2 2 0 GET complex subunit GET2 Thiolase_N PF00108.18 OAJ02779.1 - 2e-95 318.7 2.4 3.1e-95 318.1 1.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ02779.1 - 5e-43 145.4 1.8 7e-42 141.7 0.6 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ02779.1 - 2.6e-06 27.1 3.6 3.9e-05 23.2 0.8 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 OAJ02779.1 - 3 7.5 8.4 3.1 7.5 0.1 3.6 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.7 OAJ02780.1 - 0.00024 20.8 0.2 0.00047 19.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ02780.1 - 0.00089 18.8 0.1 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPT PF03151.11 OAJ02781.1 - 3.5e-31 107.9 4.8 3.5e-31 107.9 3.3 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ02781.1 - 2.8e-11 43.5 18.1 6.6e-06 26.1 3.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 OAJ02781.1 - 0.0067 15.3 16.8 0.05 12.5 11.0 2.2 1 1 0 1 1 1 1 UAA transporter family Lactamase_B PF00753.22 OAJ02782.1 - 4.6e-21 75.3 1.3 6.8e-21 74.7 0.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SAP PF02037.22 OAJ02783.1 - 2e-10 39.8 0.8 3.4e-10 39.1 0.6 1.4 1 0 0 1 1 1 1 SAP domain DUF3595 PF12166.3 OAJ02783.1 - 0.097 11.4 0.9 0.14 10.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) GTP_EFTU PF00009.22 OAJ02786.1 - 6.3e-26 90.9 0.3 7.8e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Prok-E2_C PF14459.1 OAJ02787.1 - 0.14 12.2 0.7 0.14 12.2 0.5 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family C Kei1 PF08552.6 OAJ02787.1 - 0.3 10.7 5.7 0.37 10.4 4.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DcuC PF03606.10 OAJ02787.1 - 2.3 6.3 6.5 2.7 6.1 4.5 1.2 1 1 0 1 1 1 0 C4-dicarboxylate anaerobic carrier RCC1 PF00415.13 OAJ02788.1 - 5.2e-20 71.3 11.2 0.0078 16.3 0.1 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ02788.1 - 3.3e-12 45.6 12.4 5e-08 32.3 0.8 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_5 PF12695.2 OAJ02789.1 - 3.5e-07 30.0 0.1 8.5e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ02789.1 - 6.4e-06 26.2 1.5 1.4e-05 25.0 1.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 OAJ02789.1 - 0.0046 16.3 0.1 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.9 OAJ02789.1 - 0.019 14.2 0.0 0.079 12.2 0.0 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 OAJ02789.1 - 0.038 13.6 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 OAJ02789.1 - 0.18 11.3 2.9 0.52 9.8 2.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Mitofilin PF09731.4 OAJ02790.1 - 1.9e-80 271.2 37.9 1.2e-49 169.5 20.6 2.2 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Herpes_IR6 PF06307.7 OAJ02790.1 - 0.0012 18.2 0.1 0.0027 17.0 0.1 1.5 1 0 0 1 1 1 1 Herpesvirus IR6 protein SRA1 PF07304.6 OAJ02790.1 - 0.28 10.8 4.4 0.13 12.0 0.8 2.0 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) EAP30 PF04157.11 OAJ02791.1 - 7.4e-47 159.3 0.0 1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family SRPRB PF09439.5 OAJ02792.1 - 5.4e-07 29.0 0.0 1.7e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 OAJ02792.1 - 0.0012 19.0 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 OAJ02792.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 OAJ02792.1 - 0.053 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 OAJ02792.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 OAJ02793.1 - 1.4e-17 63.7 0.1 3.8e-14 52.6 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ02793.1 - 2.5e-07 30.1 0.2 9e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 OAJ02793.1 - 1.4e-05 24.6 0.0 0.0012 18.3 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAJ02793.1 - 1.9e-05 24.5 0.3 0.042 13.6 0.1 2.8 2 1 0 2 2 2 2 Dynamin family DUF258 PF03193.11 OAJ02793.1 - 0.0078 15.4 0.1 0.017 14.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP-alpha_N PF04086.8 OAJ02793.1 - 0.044 13.1 9.5 0.074 12.4 6.6 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal KAP_NTPase PF07693.9 OAJ02793.1 - 0.073 12.0 0.0 0.29 10.0 0.0 1.9 2 0 0 2 2 2 0 KAP family P-loop domain ORC6 PF05460.8 OAJ02793.1 - 1.1 8.3 10.0 1.9 7.5 6.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PIF1 PF05970.9 OAJ02794.1 - 1.1e-21 77.2 0.0 1.4e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ02794.1 - 1.7e-08 34.2 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ02794.1 - 1.1e-05 25.0 4.5 2.9e-05 23.7 3.1 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ02794.1 - 2.2e-05 24.6 0.0 4.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ02794.1 - 0.00073 19.1 0.3 0.0039 16.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 OAJ02794.1 - 0.0018 17.7 0.1 0.0062 16.0 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 OAJ02794.1 - 0.0027 17.7 0.2 0.0083 16.1 0.1 1.6 1 1 0 2 2 2 1 AAA ATPase domain ResIII PF04851.10 OAJ02794.1 - 0.0033 17.2 0.1 0.0076 16.0 0.1 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 OAJ02794.1 - 0.0054 15.7 0.1 0.0073 15.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 OAJ02794.1 - 0.0056 16.0 0.1 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 OAJ02794.1 - 0.0058 15.8 0.2 0.013 14.7 0.1 1.6 2 0 0 2 2 2 1 PhoH-like protein NACHT PF05729.7 OAJ02794.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain T2SE PF00437.15 OAJ02794.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 OAJ02794.1 - 0.013 15.6 0.1 0.031 14.4 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 OAJ02794.1 - 0.017 14.8 0.1 0.052 13.2 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 OAJ02794.1 - 0.023 14.4 0.1 0.34 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 OAJ02794.1 - 0.024 14.1 0.3 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 OAJ02794.1 - 0.026 14.4 0.0 3 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAJ02794.1 - 0.05 13.0 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein CobA_CobO_BtuR PF02572.10 OAJ02794.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DEAD PF00270.24 OAJ02794.1 - 0.062 12.7 0.0 3.1 7.2 0.1 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 OAJ02794.1 - 0.085 12.1 0.5 0.12 11.6 0.4 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain TSC22 PF01166.13 OAJ02797.1 - 0.0031 17.4 0.2 0.0031 17.4 0.1 2.4 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF972 PF06156.8 OAJ02797.1 - 0.044 14.1 5.9 0.27 11.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) GAS PF13851.1 OAJ02797.1 - 0.099 11.8 10.9 1.3 8.1 3.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rab5-bind PF09311.6 OAJ02797.1 - 0.38 10.6 15.0 1.1 9.1 10.4 1.7 1 1 0 1 1 1 0 Rabaptin-like protein Microtub_assoc PF07989.6 OAJ02797.1 - 0.49 10.2 4.3 1.9 8.3 0.2 3.1 2 1 1 3 3 3 0 Microtubule associated Tropomyosin_1 PF12718.2 OAJ02797.1 - 0.67 9.7 11.3 0.5 10.1 4.6 2.1 2 0 0 2 2 2 0 Tropomyosin like ATG16 PF08614.6 OAJ02797.1 - 1.3 8.8 11.6 36 4.0 7.9 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ERM PF00769.14 OAJ02797.1 - 1.3 8.4 10.7 0.096 12.2 2.4 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 OAJ02797.1 - 1.8 8.3 11.3 37 4.1 4.2 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 OAJ02797.1 - 4.8 6.9 10.5 15 5.3 0.2 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein NDUFA12 PF05071.11 OAJ02798.1 - 5.6e-12 46.0 0.1 8.8e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Redoxin PF08534.5 OAJ02800.1 - 3.4e-32 111.0 0.0 3.9e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ02800.1 - 5.8e-09 35.6 0.0 7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Cellulase PF00150.13 OAJ02801.1 - 2.6e-14 53.1 3.7 3.9e-14 52.5 2.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 OAJ02801.1 - 0.017 14.2 0.1 0.06 12.4 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase AP_endonuc_2 PF01261.19 OAJ02801.1 - 0.059 12.6 0.0 2 7.6 0.0 2.3 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Transposase_21 PF02992.9 OAJ02803.1 - 1.7e-13 50.2 0.0 3.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02803.1 - 1.2e-06 27.9 0.1 2.5e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PBP1_TM PF14812.1 OAJ02803.1 - 0.027 14.7 4.7 0.032 14.5 1.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTA1 PF04479.8 OAJ02806.1 - 2.9e-34 118.5 5.1 4.1e-34 118.0 3.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Claudin_2 PF13903.1 OAJ02806.1 - 0.37 10.4 4.9 0.091 12.4 0.2 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1600 PF07667.6 OAJ02806.1 - 0.43 10.7 8.0 0.25 11.4 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Glycos_transf_3 PF00591.16 OAJ02807.1 - 4.5e-66 222.8 0.0 2.9e-62 210.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 OAJ02807.1 - 0.00044 19.7 0.1 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Acyl-CoA_dh_M PF02770.14 OAJ02807.1 - 0.099 12.1 0.2 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain HIT PF01230.18 OAJ02808.1 - 4.5e-25 88.0 0.0 5.8e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 OAJ02808.1 - 8e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.24 OAJ02810.1 - 2.8e-11 43.2 0.0 7.3e-10 38.5 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ02810.1 - 1e-07 31.7 0.1 8e-07 28.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02810.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3357 PF11837.3 OAJ02811.1 - 0.046 13.5 1.0 1 9.2 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) UPF0370 PF13980.1 OAJ02811.1 - 0.52 10.1 3.0 0.43 10.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) RRM_6 PF14259.1 OAJ02814.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ02814.1 - 1.3e-05 24.7 0.0 5.4e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ02814.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 OAJ02814.1 - 0.0057 16.5 0.3 0.0057 16.5 0.2 2.1 3 0 0 3 3 3 1 FYVE zinc finger zf-CCCH_2 PF14608.1 OAJ02814.1 - 0.0058 16.5 2.4 0.018 15.0 1.7 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type Limkain-b1 PF11608.3 OAJ02814.1 - 0.01 15.5 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 Limkain b1 zf-CCCH PF00642.19 OAJ02814.1 - 0.018 14.7 1.2 0.018 14.7 0.8 2.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ALG3 PF05208.8 OAJ02815.1 - 1.2e-121 406.4 12.1 1.6e-121 406.0 8.4 1.2 1 0 0 1 1 1 1 ALG3 protein Drc1-Sld2 PF11719.3 OAJ02816.1 - 1e-07 31.4 0.2 1e-07 31.4 0.1 3.6 2 1 2 4 4 4 2 DNA replication and checkpoint protein Clathrin PF00637.15 OAJ02817.1 - 7.6e-15 54.7 0.3 4.5e-06 26.3 0.0 3.4 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.3 OAJ02817.1 - 1e-08 34.8 0.3 2.5e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 OAJ02817.1 - 0.038 13.8 6.7 0.069 12.9 4.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 OAJ02817.1 - 0.23 11.2 6.7 0.4 10.4 4.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ02817.1 - 0.32 11.0 5.9 0.58 10.2 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 OAJ02817.1 - 1.8 8.3 6.0 3.4 7.4 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 OAJ02817.1 - 3.4 7.4 6.8 6.1 6.6 4.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 OAJ02817.1 - 4.6 7.4 6.0 8.6 6.5 4.1 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger 2-oxoacid_dh PF00198.18 OAJ02818.1 - 1.5e-58 197.8 0.0 2.7e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ02818.1 - 4.4e-19 67.8 0.1 9.5e-19 66.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ02818.1 - 6.2e-14 51.3 0.3 1.3e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ02818.1 - 0.024 14.2 0.1 0.21 11.2 0.1 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like PYNP_C PF07831.8 OAJ02818.1 - 0.072 12.5 0.0 13 5.3 0.0 2.4 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Peptidase_M23 PF01551.17 OAJ02818.1 - 0.12 12.4 0.0 1.4 9.0 0.0 2.2 1 1 1 2 2 2 0 Peptidase family M23 HTH_17 PF12728.2 OAJ02818.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain FdhE PF04216.7 OAJ02818.1 - 0.22 11.2 2.3 0.48 10.0 1.6 1.5 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Myc_N PF01056.13 OAJ02820.1 - 0.04 13.0 0.2 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 OAJ02820.1 - 0.062 11.2 0.2 0.071 11.0 0.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ02820.1 - 0.28 10.6 4.7 0.41 10.1 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 OAJ02820.1 - 0.31 10.7 1.9 0.46 10.2 1.3 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.7 OAJ02820.1 - 1.2 8.3 4.9 1.5 8.0 3.4 1.1 1 0 0 1 1 1 0 NOA36 protein MA3 PF02847.12 OAJ02822.1 - 4.5e-27 93.9 0.1 8.3e-27 93.1 0.1 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 OAJ02822.1 - 2.1e-26 92.6 0.1 5e-26 91.4 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain FAM176 PF14851.1 OAJ02822.1 - 0.75 9.4 5.4 9.1 5.9 1.9 2.8 3 0 0 3 3 3 0 FAM176 family Sigma70_ner PF04546.8 OAJ02822.1 - 4.1 6.9 10.5 1.3 8.6 3.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region MFS_1 PF07690.11 OAJ02823.1 - 2.2e-07 29.9 23.6 2.2e-07 29.9 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.7 OAJ02823.1 - 4.6 6.9 9.4 8 6.2 0.4 3.0 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB FeoB_C PF07664.7 OAJ02823.1 - 9.4 5.7 8.9 18 4.8 0.7 3.1 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus RXT2_N PF08595.6 OAJ02824.1 - 1.4e-05 24.9 0.2 0.2 11.4 0.0 2.8 2 0 0 2 2 2 2 RXT2-like, N-terminal Zn_clus PF00172.13 OAJ02825.1 - 0.024 14.5 6.8 0.068 13.0 4.6 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arrestin_C PF02752.17 OAJ02826.1 - 0.0064 16.6 0.0 0.047 13.7 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain PBP PF01161.15 OAJ02827.1 - 2.7e-15 56.4 0.0 4.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Speriolin_N PF15058.1 OAJ02827.1 - 8.6 6.2 10.2 2.8 7.8 0.1 2.3 1 1 0 2 2 2 0 Speriolin N terminus FAD_binding_3 PF01494.14 OAJ02828.1 - 1.1e-21 77.2 0.0 2.4e-07 30.1 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 OAJ02828.1 - 1.6e-07 30.6 0.0 1.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ02828.1 - 2.1e-06 28.0 0.0 0.00027 21.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 OAJ02828.1 - 1.2e-05 24.3 0.0 0.061 12.1 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 OAJ02828.1 - 5.1e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 OAJ02828.1 - 0.00014 20.4 0.0 0.00022 19.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 OAJ02828.1 - 0.00021 20.7 0.0 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 OAJ02828.1 - 0.00062 18.7 0.0 0.001 18.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 OAJ02828.1 - 0.001 17.8 0.0 0.66 8.5 0.0 2.4 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.2 OAJ02828.1 - 0.0016 17.5 0.3 0.0026 16.8 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAJ02828.1 - 0.003 17.2 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 OAJ02828.1 - 0.0078 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ02828.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 OAJ02828.1 - 0.024 14.4 0.0 0.061 13.0 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 OAJ02828.1 - 0.027 13.3 0.1 0.053 12.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 OAJ02828.1 - 0.027 13.8 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 OAJ02828.1 - 0.037 14.0 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAJ02828.1 - 0.072 12.9 0.5 0.26 11.1 0.2 2.0 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 OAJ02828.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Nop25 PF09805.4 OAJ02829.1 - 8.3e-18 64.7 18.8 8.3e-18 64.7 13.0 3.4 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) GRP PF07172.6 OAJ02829.1 - 0.025 15.0 11.4 0.025 15.0 7.9 2.2 2 0 0 2 2 2 0 Glycine rich protein family MAT1 PF06391.8 OAJ02830.1 - 9.2e-39 133.0 10.8 1.2e-38 132.7 7.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 OAJ02830.1 - 0.00011 21.7 8.3 0.00057 19.4 6.2 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ02830.1 - 0.00053 19.6 7.7 0.0019 17.9 5.5 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ02830.1 - 0.0023 17.5 11.0 0.015 14.9 8.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ02830.1 - 0.0035 17.3 9.8 0.083 12.9 7.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 OAJ02830.1 - 0.0055 16.2 7.8 0.061 12.9 2.7 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-ISL3 PF14690.1 OAJ02830.1 - 0.0076 16.2 1.4 0.13 12.3 0.1 2.5 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-RING_2 PF13639.1 OAJ02830.1 - 0.11 12.3 10.2 1.1 9.1 7.4 2.1 1 1 1 2 2 2 0 Ring finger domain DZR PF12773.2 OAJ02830.1 - 1.9 8.3 9.2 5.7 6.8 6.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon NAD_binding_2 PF03446.10 OAJ02831.1 - 1.3e-22 80.3 0.2 1.9e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 OAJ02831.1 - 4.4e-08 33.2 0.0 8.3e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 OAJ02831.1 - 4.4e-06 27.0 0.5 0.00066 20.0 0.0 2.9 2 1 1 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 OAJ02831.1 - 2.1e-05 24.6 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 OAJ02831.1 - 0.031 13.9 1.0 0.6 9.7 0.7 2.2 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl_transf_3 PF01757.17 OAJ02832.1 - 7.6e-06 24.9 31.2 1.2e-05 24.3 21.6 1.3 1 0 0 1 1 1 1 Acyltransferase family JmjC PF02373.17 OAJ02833.1 - 3.9e-12 46.4 0.0 1.3e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 OAJ02833.1 - 1e-08 35.0 0.0 2.8e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 OAJ02833.1 - 0.0089 15.3 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.2 OAJ02833.1 - 0.016 14.9 0.1 0.05 13.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like CTP_synth_N PF06418.9 OAJ02834.1 - 6.1e-116 386.3 0.0 8.5e-116 385.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 OAJ02834.1 - 1.5e-47 161.5 0.0 3.6e-37 127.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.18 OAJ02834.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Acetate_kinase PF00871.12 OAJ02835.1 - 8e-61 205.6 0.0 1.9e-43 148.5 0.0 3.1 3 0 0 3 3 3 3 Acetokinase family Transposase_21 PF02992.9 OAJ02839.1 - 9.1e-16 57.6 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02839.1 - 3.1e-05 23.4 0.3 5.4e-05 22.6 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HpaP PF09483.5 OAJ02839.1 - 0.0054 16.6 2.6 0.0054 16.6 1.8 2.3 2 0 0 2 2 2 1 Type III secretion protein (HpaP) Auto_anti-p27 PF06677.7 OAJ02839.1 - 0.18 11.5 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NPV_P10 PF05531.7 OAJ02840.1 - 3.1 8.1 4.9 13 6.0 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NUC173 PF08161.7 OAJ02841.1 - 1.1e-37 129.3 0.0 5.3e-36 123.8 0.0 3.2 2 1 0 2 2 2 1 NUC173 domain CAS_CSE1 PF03378.10 OAJ02841.1 - 0.065 11.5 0.1 0.19 10.0 0.1 1.7 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus tRNA_bind_2 PF13725.1 OAJ02842.1 - 0.04 14.0 0.0 0.078 13.0 0.0 1.5 1 1 0 1 1 1 0 Possible tRNA binding domain Phosphorylase PF00343.15 OAJ02842.1 - 0.045 11.6 0.0 0.055 11.3 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase DUF2092 PF09865.4 OAJ02842.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) CDC73 PF05179.9 OAJ02844.1 - 3.4e-40 138.1 9.6 9.3e-30 103.9 1.0 2.6 3 0 0 3 3 3 2 RNA pol II accessory factor, Cdc73 family DUF1436 PF07262.6 OAJ02844.1 - 0.13 11.7 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Abhydrolase_6 PF12697.2 OAJ02845.1 - 4.2e-15 56.2 1.6 9.9e-09 35.4 0.6 3.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family WBS28 PF15164.1 OAJ02846.1 - 0.001 18.2 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF2243 PF10002.4 OAJ02846.1 - 0.11 12.3 0.6 0.13 12.0 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) Abhydrolase_3 PF07859.8 OAJ02847.1 - 2.7e-38 131.6 0.0 6.3e-31 107.5 0.1 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ02847.1 - 9.7e-10 37.6 0.0 2.9e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 OAJ02847.1 - 3.1e-05 23.7 0.0 8.8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Transketolase_C PF02780.15 OAJ02847.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain COesterase PF00135.23 OAJ02847.1 - 0.18 10.4 0.0 0.63 8.6 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family DPBB_1 PF03330.13 OAJ02848.1 - 0.00073 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ribonuc_red_sm PF00268.16 OAJ02849.1 - 2.3e-119 397.5 1.8 2.8e-119 397.3 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Got1 PF04178.7 OAJ02850.1 - 1.4e-23 83.2 21.7 1.8e-23 82.8 15.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4396 PF14342.1 OAJ02850.1 - 1.2 9.2 11.9 2.1 8.4 8.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) DUF4187 PF13821.1 OAJ02851.1 - 2.4e-14 52.6 4.9 2.4e-14 52.6 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 OAJ02851.1 - 0.0034 17.1 0.1 0.01 15.6 0.1 1.7 1 0 0 1 1 1 1 G-patch domain CDP-OH_P_transf PF01066.16 OAJ02853.1 - 3e-18 65.9 7.4 7.1e-18 64.7 5.0 1.8 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase GRIM-19 PF06212.7 OAJ02854.1 - 5.6e-34 116.6 0.0 6.9e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Aldo_ket_red PF00248.16 OAJ02855.1 - 1.7e-44 151.7 0.0 2e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family K_trans PF02705.11 OAJ02856.1 - 3.8e-154 513.9 8.6 4.6e-154 513.6 6.0 1.1 1 0 0 1 1 1 1 K+ potassium transporter MRI PF15325.1 OAJ02856.1 - 3.5 8.6 6.3 25 5.9 0.1 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection ETF_alpha PF00766.14 OAJ02858.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Fungal_trans PF04082.13 OAJ02859.1 - 2.6e-16 59.2 3.3 5.8e-16 58.1 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ02859.1 - 6.1e-05 22.8 7.5 0.00011 21.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Daxx PF03344.10 OAJ02859.1 - 0.05 12.0 9.8 0.078 11.4 6.8 1.2 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 OAJ02859.1 - 0.071 11.4 15.1 0.16 10.3 10.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 OAJ02859.1 - 0.09 10.7 7.3 0.13 10.2 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 OAJ02859.1 - 0.66 9.5 10.5 1.1 8.8 7.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2890 PF11081.3 OAJ02859.1 - 0.76 9.7 8.6 1.7 8.6 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 OAJ02859.1 - 1.3 9.2 18.7 3.7 7.8 13.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IFT57 PF10498.4 OAJ02859.1 - 2.8 6.6 7.4 59 2.2 5.5 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Nop14 PF04147.7 OAJ02859.1 - 4.5 5.0 18.1 8.1 4.2 12.6 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 OAJ02859.1 - 7.2 6.1 11.1 15 5.1 7.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Lin-8 PF03353.10 OAJ02859.1 - 7.9 5.6 7.2 15 4.7 5.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.6 OAJ02859.1 - 8.6 4.5 5.1 14 3.8 3.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Mito_carr PF00153.22 OAJ02860.1 - 1.2e-38 130.6 4.1 1.8e-14 53.1 0.1 4.5 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF3534 PF12053.3 OAJ02860.1 - 0.032 14.1 0.8 0.093 12.6 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) ORC3_N PF07034.6 OAJ02861.1 - 1.5e-17 63.5 0.8 9.5e-14 51.0 0.0 3.7 3 1 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus Daxx PF03344.10 OAJ02861.1 - 0.0023 16.5 20.0 0.0023 16.5 13.9 1.7 2 0 0 2 2 2 1 Daxx Family F-box-like PF12937.2 OAJ02863.1 - 0.00023 20.8 0.1 0.00081 19.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 OAJ02863.1 - 0.11 12.6 4.1 34 5.0 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 OAJ02863.1 - 0.24 11.7 5.8 30 5.4 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 OAJ02863.1 - 1.2 8.8 3.1 76 3.0 1.5 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) RNA_pol_3_Rpc31 PF11705.3 OAJ02870.1 - 4.4e-33 115.1 6.6 5.9e-33 114.7 4.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Condensation PF00668.15 OAJ02870.1 - 0.19 10.5 1.2 0.29 9.9 0.8 1.2 1 0 0 1 1 1 0 Condensation domain E1-E2_ATPase PF00122.15 OAJ02871.1 - 5.5e-63 212.0 5.1 2.3e-62 210.0 2.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ02871.1 - 7e-49 165.8 5.0 8.2e-48 162.3 1.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ02871.1 - 1.2e-32 114.0 0.9 4.8e-32 112.1 0.2 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ02871.1 - 5.5e-20 70.6 0.0 1.3e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 OAJ02871.1 - 2.1e-19 69.2 0.0 3.9e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ02871.1 - 5.1e-15 56.1 0.2 1.4e-14 54.7 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ02871.1 - 2.7e-06 27.1 0.8 5.4e-05 22.9 0.5 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ02871.1 - 0.023 14.9 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MPC PF03650.8 OAJ02872.1 - 1.2e-38 131.6 0.1 1.5e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) GARS_N PF02844.10 OAJ02872.1 - 0.019 15.4 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Pex19 PF04614.7 OAJ02873.1 - 5.4e-56 189.9 0.2 1.8e-55 188.2 0.0 1.8 1 1 1 2 2 2 1 Pex19 protein family Sigma70_ner PF04546.8 OAJ02873.1 - 2.9 7.4 9.9 9.3 5.8 3.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region ALAD PF00490.16 OAJ02874.1 - 1.2e-118 395.7 0.0 1.4e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase FHA PF00498.21 OAJ02875.1 - 0.019 15.0 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 FHA domain RVT_1 PF00078.22 OAJ02876.1 - 4.9e-18 65.2 0.0 8.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02876.1 - 1.6e-15 57.2 0.0 3.1e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ02876.1 - 0.0059 17.0 0.1 0.019 15.4 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.8 OAJ02876.1 - 0.022 13.2 0.0 0.035 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Exc PF07825.6 OAJ02876.1 - 0.037 13.7 0.1 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Excisionase-like protein RVP PF00077.15 OAJ02876.1 - 0.26 11.2 0.0 0.61 10.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease HALZ PF02183.13 OAJ02879.1 - 0.0011 18.6 2.1 0.033 13.8 1.2 3.3 2 1 1 3 3 3 2 Homeobox associated leucine zipper DUF1319 PF07028.6 OAJ02879.1 - 0.0027 17.8 6.6 0.1 12.7 0.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF1319) priB_priC PF07445.7 OAJ02879.1 - 0.003 17.0 9.3 0.0061 16.0 2.5 2.5 1 1 1 2 2 2 1 Primosomal replication protein priB and priC V_ATPase_I PF01496.14 OAJ02879.1 - 0.012 13.5 3.8 0.017 13.0 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_porin PF12795.2 OAJ02879.1 - 0.03 13.6 12.0 0.011 15.0 4.5 2.5 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DMPK_coil PF08826.5 OAJ02879.1 - 0.04 13.8 0.5 0.04 13.8 0.4 3.9 3 1 2 5 5 5 0 DMPK coiled coil domain like Cast PF10174.4 OAJ02879.1 - 0.15 10.1 26.0 4.9 5.0 0.1 2.8 2 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Myosin_tail_1 PF01576.14 OAJ02879.1 - 0.45 8.1 26.5 5.7 4.5 13.7 2.9 2 1 0 2 2 2 0 Myosin tail DivIC PF04977.10 OAJ02879.1 - 0.51 9.8 7.6 0.095 12.2 0.4 2.8 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 OAJ02879.1 - 0.74 9.5 14.2 1.6 8.4 0.7 3.3 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 Filament PF00038.16 OAJ02879.1 - 0.82 9.0 21.3 0.069 12.5 6.5 2.9 2 1 1 3 3 3 0 Intermediate filament protein CorA PF01544.13 OAJ02879.1 - 2.1 7.2 8.0 0.71 8.8 3.6 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 OAJ02879.1 - 4.2 7.4 7.2 1 9.4 2.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 OAJ02879.1 - 4.2 5.9 16.7 6.4 5.3 1.7 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 OAJ02879.1 - 7.8 7.2 8.8 4.7 8.0 0.2 3.3 3 1 1 4 4 3 0 Occludin homology domain APG6 PF04111.7 OAJ02879.1 - 9.4 5.1 16.8 0.51 9.3 4.5 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Histone PF00125.19 OAJ02880.1 - 7.9e-19 67.5 1.1 1.2e-18 66.9 0.8 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 OAJ02880.1 - 9.6e-05 21.8 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 OAJ02880.1 - 0.0002 21.4 0.0 0.00043 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ02880.1 - 0.00035 20.5 0.2 0.00069 19.6 0.2 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1931 PF09123.6 OAJ02880.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Bromo_TP PF07524.8 OAJ02880.1 - 0.073 12.8 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 OAJ02880.1 - 0.077 12.7 0.2 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Transposase_21 PF02992.9 OAJ02881.1 - 1.7e-22 79.6 0.0 3.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ02881.1 - 0.004 16.6 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) FliT PF05400.8 OAJ02882.1 - 0.037 14.4 1.3 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DUF605 PF04652.11 OAJ02882.1 - 4.4 6.6 30.4 5.6 6.2 21.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF3533 PF12051.3 OAJ02885.1 - 8.5e-76 255.1 14.9 9.9e-76 254.9 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DDE_3 PF13358.1 OAJ02887.1 - 9.1e-09 35.2 0.0 1.7e-08 34.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ02887.1 - 3.5e-05 23.2 0.0 5.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix Arg_repressor PF01316.16 OAJ02887.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain DDE_Tnp_ISAZ013 PF07592.6 OAJ02887.1 - 0.034 12.8 0.1 0.17 10.6 0.1 1.8 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain peroxidase PF00141.18 OAJ02889.1 - 7.7e-51 172.7 0.0 1.1e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase GalKase_gal_bdg PF10509.4 OAJ02889.1 - 0.14 11.4 0.0 0.37 10.0 0.0 1.7 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Pyrophosphatase PF00719.14 OAJ02890.1 - 9.2e-54 181.1 0.2 1.2e-53 180.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DNA_pol_B_thumb PF14791.1 OAJ02891.1 - 1.3e-21 75.9 0.0 2.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 OAJ02891.1 - 8.4e-20 70.9 0.0 1.9e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 OAJ02891.1 - 1.2e-06 28.6 0.0 8.2e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 OAJ02891.1 - 1.2e-05 24.7 0.0 3.2e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 OAJ02891.1 - 0.0017 18.4 0.0 0.0058 16.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Glyco_transf_90 PF05686.7 OAJ02892.1 - 5.3e-23 81.3 6.2 2.9e-20 72.3 3.4 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Glyco_transf_90 PF05686.7 OAJ02893.1 - 9.9e-26 90.3 7.4 9.1e-23 80.5 4.7 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3533 PF12051.3 OAJ02894.1 - 2.4e-73 247.0 22.3 2.9e-73 246.8 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ChaC PF04752.7 OAJ02895.1 - 4.4e-50 170.1 0.0 9.3e-50 169.0 0.0 1.6 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.26 OAJ02895.1 - 6.5e-28 96.2 1.0 1.6e-27 94.9 0.7 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 OAJ02895.1 - 2e-09 37.2 0.6 4.5e-09 36.2 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ02895.1 - 4.9e-06 26.5 0.5 9.2e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 OAJ02895.1 - 0.002 18.2 0.1 0.0056 16.7 0.1 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Lactamase_B_3 PF13483.1 OAJ02896.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DAHP_synth_1 PF00793.15 OAJ02899.1 - 1.7e-93 312.2 0.0 2.1e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DUF1522 PF07482.6 OAJ02899.1 - 0.066 13.3 0.4 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) DUF1767 PF08585.7 OAJ02900.1 - 8.4e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Ribosomal_60s PF00428.14 OAJ02900.1 - 0.073 13.4 1.1 0.23 11.9 0.8 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1917 PF08939.5 OAJ02901.1 - 2.1e-12 47.3 0.8 2.1e-12 47.3 0.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) F-box-like PF12937.2 OAJ02903.1 - 0.0014 18.2 0.1 0.0046 16.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ02903.1 - 0.096 12.3 0.1 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 F-box domain RMF PF04957.7 OAJ02903.1 - 3.3 7.4 5.4 2.2 8.0 0.3 2.4 1 1 1 2 2 2 0 Ribosome modulation factor Thioredoxin PF00085.15 OAJ02904.1 - 4.1e-26 90.6 0.0 1e-25 89.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ02904.1 - 1.1e-05 25.4 0.0 0.00018 21.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ02904.1 - 6.4e-05 23.1 0.0 0.00036 20.7 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 OAJ02904.1 - 0.014 15.4 0.0 0.056 13.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 OAJ02904.1 - 0.038 14.0 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 OAJ02904.1 - 0.062 12.8 0.0 0.16 11.4 0.0 1.6 1 1 1 2 2 2 0 Redoxin GHMP_kinases_N PF00288.21 OAJ02904.1 - 0.09 12.8 0.3 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 GHMP kinases N terminal domain AhpC-TSA PF00578.16 OAJ02904.1 - 0.097 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family CorA PF01544.13 OAJ02905.1 - 2.6e-19 69.3 0.6 2.6e-06 26.7 0.2 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Mog1 PF04603.7 OAJ02906.1 - 1.1e-30 106.3 0.2 2.6e-30 105.2 0.1 1.5 1 1 0 1 1 1 1 Ran-interacting Mog1 protein IMPDH PF00478.20 OAJ02907.1 - 1.7e-138 461.3 0.0 2.1e-136 454.4 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 OAJ02907.1 - 2.2e-18 65.7 0.1 4.9e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 OAJ02907.1 - 5.3e-13 48.8 4.0 1.2e-09 37.7 1.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ02907.1 - 4.6e-09 35.5 4.9 5.3e-09 35.3 2.3 1.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 OAJ02907.1 - 1.4e-07 31.0 3.4 4.2e-06 26.1 0.5 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 OAJ02907.1 - 0.00027 20.0 2.0 0.00027 20.0 1.4 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 OAJ02907.1 - 0.00038 19.4 0.3 0.0012 17.8 0.1 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.14 OAJ02907.1 - 0.0093 15.1 0.6 0.044 12.9 0.0 2.2 2 0 0 2 2 2 1 KDPG and KHG aldolase Dus PF01207.12 OAJ02907.1 - 0.029 13.2 1.0 0.55 8.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF561 PF04481.7 OAJ02907.1 - 0.13 11.1 1.3 0.6 9.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) PcrB PF01884.12 OAJ02907.1 - 0.15 11.3 1.4 2.6 7.2 0.0 2.9 3 0 0 3 3 3 0 PcrB family Acetyltransf_8 PF13523.1 OAJ02908.1 - 4.2e-38 130.6 0.6 5.9e-38 130.1 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rcd1 PF04078.8 OAJ02909.1 - 5.6e-126 418.7 1.2 7.5e-126 418.3 0.8 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like APC_CDC26 PF10471.4 OAJ02909.1 - 8.6 7.1 7.1 2.5 8.9 1.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Daxx PF03344.10 OAJ02910.1 - 8.5 4.7 26.9 1.4 7.2 14.4 2.7 2 0 0 2 2 2 0 Daxx Family ING PF12998.2 OAJ02911.1 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 OAJ02911.1 - 3.6e-08 32.9 7.4 5.5e-08 32.3 5.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ02911.1 - 0.011 15.0 1.7 0.019 14.2 1.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.3 OAJ02911.1 - 0.14 12.2 0.5 0.26 11.4 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SPC12 PF06645.8 OAJ02912.1 - 2.1e-23 81.9 0.1 2.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec20 PF03908.8 OAJ02914.1 - 1.4e-21 75.9 1.5 4.6e-21 74.3 1.1 1.9 1 0 0 1 1 1 1 Sec20 Scaffolding_pro PF11418.3 OAJ02914.1 - 0.036 14.3 2.2 0.086 13.1 0.1 2.5 2 1 1 3 3 3 0 Phi29 scaffolding protein MS_channel PF00924.13 OAJ02915.1 - 2.5e-22 79.2 0.0 3.7e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ02915.1 - 0.0013 17.8 0.1 0.0036 16.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAJ02915.1 - 0.014 15.2 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 OAJ02915.1 - 0.03 14.4 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 OAJ02915.1 - 0.038 13.3 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 EF hand ADH_N PF08240.7 OAJ02916.1 - 6.1e-11 42.0 0.7 1.3e-09 37.7 0.4 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ02916.1 - 1.1e-08 34.7 0.1 2.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ02916.1 - 0.00094 20.0 0.0 0.0029 18.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 OAJ02917.1 - 5.9e-08 31.9 0.2 1.3e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ02917.1 - 1.3e-07 31.4 5.4 2.1e-07 30.7 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Siva PF05458.7 OAJ02917.1 - 3.8 7.0 8.5 0.055 13.0 0.7 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) bZIP_1 PF00170.16 OAJ02918.1 - 2.3e-05 24.2 23.9 0.00057 19.7 10.1 2.5 2 0 0 2 2 2 2 bZIP transcription factor Nop14 PF04147.7 OAJ02918.1 - 0.00041 18.4 22.2 0.00041 18.4 15.4 2.7 3 0 0 3 3 3 1 Nop14-like family YL1 PF05764.8 OAJ02918.1 - 0.0024 17.5 13.9 0.0024 17.5 9.7 3.7 3 1 1 4 4 4 1 YL1 nuclear protein bZIP_2 PF07716.10 OAJ02918.1 - 0.015 15.1 14.0 0.015 15.1 9.7 3.7 3 1 0 3 3 3 0 Basic region leucine zipper DUF904 PF06005.7 OAJ02918.1 - 0.022 15.0 0.6 0.022 15.0 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 OAJ02918.1 - 0.069 13.5 0.1 0.069 13.5 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF972) eIF-3c_N PF05470.7 OAJ02918.1 - 0.8 7.7 8.7 0.099 10.7 1.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 OAJ02918.1 - 2.1 7.5 39.0 0.25 10.5 16.7 3.0 3 0 0 3 3 3 0 SDA1 SAPS PF04499.10 OAJ02918.1 - 8 4.9 12.0 0.76 8.3 4.6 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein MS_channel PF00924.13 OAJ02919.1 - 1.1e-14 54.2 0.3 2.6e-14 53.0 0.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 OAJ02919.1 - 6.1e-05 22.0 0.1 0.00014 20.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 OAJ02919.1 - 0.0002 20.9 0.1 0.00074 19.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 OAJ02919.1 - 0.00077 19.5 0.1 0.0021 18.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 OAJ02919.1 - 0.02 14.2 0.2 0.045 13.1 0.1 1.6 1 0 0 1 1 1 0 EF hand DUF4231 PF14015.1 OAJ02919.1 - 3.6 7.6 9.9 3 7.8 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PCI PF01399.22 OAJ02920.1 - 0.0002 21.6 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 OAJ02920.1 - 0.031 14.1 0.1 0.09 12.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat KH_1 PF00013.24 OAJ02921.1 - 2.2e-09 36.7 0.1 1.6e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 KH domain KH_3 PF13014.1 OAJ02921.1 - 1.9e-05 24.1 2.5 0.00035 20.1 0.1 2.7 3 0 0 3 3 3 1 KH domain Trp_repressor PF01371.14 OAJ02921.1 - 0.038 13.9 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein GRP PF07172.6 OAJ02921.1 - 5.8 7.4 18.5 2.2 8.7 9.6 2.3 2 0 0 2 2 2 0 Glycine rich protein family Asp PF00026.18 OAJ02922.1 - 6.4e-61 206.3 8.7 1.5e-60 205.1 6.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ02922.1 - 3.4e-06 26.6 0.0 0.00011 21.7 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 OAJ02922.1 - 8.5e-06 25.8 6.0 1.6e-05 24.9 2.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ02922.1 - 0.00026 21.4 4.4 0.0034 17.8 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease MutS_V PF00488.16 OAJ02923.1 - 1.5e-95 319.0 0.0 2.2e-95 318.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ02923.1 - 1e-35 123.4 2.5 1.4e-35 122.9 0.4 2.1 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 OAJ02923.1 - 4.1e-19 68.5 0.4 2.5e-18 66.0 0.0 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 OAJ02923.1 - 1.3e-15 57.6 0.0 4.6e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 OAJ02923.1 - 2.5e-15 56.4 0.0 7.9e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MF_alpha_N PF05436.6 OAJ02923.1 - 0.0077 15.8 0.1 0.086 12.5 0.0 2.6 2 0 0 2 2 2 1 Mating factor alpha precursor N-terminus DUF4404 PF14357.1 OAJ02923.1 - 6.1 7.3 9.0 0.26 11.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF619 PF04768.8 OAJ02924.1 - 7.2e-44 149.2 0.0 1.2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 OAJ02924.1 - 5.3e-24 84.8 0.0 1.4e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 OAJ02924.1 - 5.5e-23 81.7 0.0 1.2e-22 80.6 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 OAJ02924.1 - 7.4e-11 42.2 0.0 2e-10 40.8 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 OAJ02924.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pam16 PF03656.8 OAJ02924.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Pam16 p450 PF00067.17 OAJ02926.1 - 0.00028 19.5 0.0 0.00033 19.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 START PF01852.14 OAJ02927.1 - 0.0039 16.5 0.1 0.0094 15.2 0.0 1.5 2 0 0 2 2 2 1 START domain Abi PF02517.11 OAJ02928.1 - 4.8e-15 55.4 4.4 1.8e-14 53.6 3.0 2.0 1 0 0 1 1 1 1 CAAX protease self-immunity F-box-like PF12937.2 OAJ02928.1 - 0.00078 19.1 0.0 0.0048 16.5 0.0 2.3 1 1 0 1 1 1 1 F-box-like Gly_transf_sug PF04488.10 OAJ02929.1 - 7.8e-07 29.4 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Apolipoprotein PF01442.13 OAJ02935.1 - 0.0011 18.5 2.4 0.0012 18.3 1.7 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain GrpE PF01025.14 OAJ02935.1 - 0.0019 17.7 4.2 0.0022 17.5 2.0 1.5 1 1 0 1 1 1 1 GrpE LUC7 PF03194.10 OAJ02935.1 - 0.016 14.7 0.9 0.02 14.4 0.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus MIF4G_like_2 PF09090.6 OAJ02935.1 - 0.15 11.2 0.8 0.21 10.8 0.6 1.1 1 0 0 1 1 1 0 MIF4G like V_ATPase_I PF01496.14 OAJ02935.1 - 0.53 8.0 1.7 0.6 7.8 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3712 PF12505.3 OAJ02938.1 - 4.2e-112 369.2 38.6 5.2e-24 84.6 0.2 9.6 10 0 0 10 10 10 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ02938.1 - 5.6e-08 33.0 19.8 0.13 12.6 0.0 9.2 10 0 0 10 10 10 4 Late embryogenesis abundant protein Apt1 PF10351.4 OAJ02938.1 - 7.8 5.2 2.8 12 4.5 2.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cupin_8 PF13621.1 OAJ02939.1 - 1.3e-50 172.2 0.0 1.7e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 OAJ02939.1 - 0.00039 19.8 0.0 0.65 9.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain JmjC PF02373.17 OAJ02939.1 - 0.0015 18.7 0.1 0.047 13.9 0.0 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 OAJ02939.1 - 0.093 11.9 0.2 0.23 10.6 0.1 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Proteasome PF00227.21 OAJ02940.1 - 6.2e-55 185.4 0.0 7.7e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ02940.1 - 5.6e-14 51.1 0.1 9.8e-14 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Retrotrans_gag PF03732.12 OAJ02941.1 - 0.00056 19.9 0.2 0.00099 19.1 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 OAJ02942.1 - 7.9e-05 23.0 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ02942.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PI3_PI4_kinase PF00454.22 OAJ02943.1 - 2.9e-29 102.2 0.0 5.3e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF2890 PF11081.3 OAJ02944.1 - 0.004 17.2 1.5 0.0097 15.9 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Sporozoite_P67 PF05642.6 OAJ02944.1 - 1.1 7.0 10.1 0.27 9.0 0.5 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 OAJ02944.1 - 2.4 8.4 5.9 6.4 7.1 4.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Transposase_21 PF02992.9 OAJ02948.1 - 3.1e-31 108.2 6.1 5.4e-18 64.9 0.0 4.3 5 0 0 5 5 5 2 Transposase family tnp2 LON PF02190.11 OAJ02948.1 - 0.00085 19.0 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Glyco_hydro_2 PF00703.16 OAJ02950.1 - 0.001 19.5 0.2 0.0025 18.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 DUF2413 PF10310.4 OAJ02950.1 - 0.0029 16.4 8.6 0.0035 16.2 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Nop14 PF04147.7 OAJ02950.1 - 2.2 6.1 8.4 2.7 5.8 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF566 PF04484.7 OAJ02950.1 - 6.1 6.2 11.3 7.7 5.9 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) rve PF00665.21 OAJ02951.1 - 2e-13 50.4 0.0 5.3e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 OAJ02951.1 - 0.00025 20.4 0.2 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ETC_C1_NDUFA4 PF04800.7 OAJ02952.1 - 1.2e-31 108.5 0.1 1.9e-31 107.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region TRIC PF05197.8 OAJ02953.1 - 0.0002 20.8 0.3 0.0009 18.7 0.1 2.1 1 1 1 2 2 2 1 TRIC channel UPF0126 PF03458.8 OAJ02953.1 - 0.00027 20.5 3.7 0.2 11.3 0.3 2.8 2 0 0 2 2 2 2 UPF0126 domain DS PF01916.12 OAJ02954.1 - 2e-134 447.4 0.0 2.4e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase VCBS PF13517.1 OAJ02957.1 - 3.2e-19 69.0 17.8 7.3e-06 26.2 0.3 6.1 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 OAJ02957.1 - 1.6e-14 53.1 7.2 0.00042 19.9 0.3 6.1 5 1 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 OAJ02957.1 - 1.8e-05 24.2 0.8 9.7 5.5 0.0 5.1 5 0 0 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region Transglut_N PF00868.15 OAJ02958.1 - 0.0015 18.5 0.1 0.0038 17.2 0.1 1.7 2 0 0 2 2 2 1 Transglutaminase family RVT_1 PF00078.22 OAJ02959.1 - 3.1e-21 75.7 0.0 8.3e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ02959.1 - 3.9e-13 49.5 0.0 8.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Dimer_Tnp_hAT PF05699.9 OAJ02960.1 - 7.1e-05 22.3 0.0 0.00024 20.6 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NST1 PF13945.1 OAJ02962.1 - 0.14 12.2 3.0 0.43 10.6 2.1 1.8 1 0 0 1 1 1 0 Salt tolerance down-regulator Apt1 PF10351.4 OAJ02962.1 - 3.5 6.3 4.3 5.7 5.6 3.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain HORMA PF02301.13 OAJ02963.1 - 5.9e-18 65.1 0.0 7.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain SET PF00856.23 OAJ02965.1 - 3.8e-26 92.3 0.0 1e-24 87.6 0.0 3.2 2 0 0 2 2 2 1 SET domain N-SET PF11764.3 OAJ02965.1 - 8.8e-16 58.2 0.4 6.8e-15 55.3 0.1 2.6 1 1 1 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N DDE_Tnp_2 PF04693.7 OAJ02965.1 - 0.85 8.5 0.0 1.3 7.9 0.0 1.1 1 0 0 1 1 1 0 Archaeal putative transposase ISC1217 UCH PF00443.24 OAJ02966.1 - 3.1e-36 124.8 0.0 1.1e-35 123.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ02966.1 - 1.1e-07 31.5 0.0 0.069 12.5 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase CDC45 PF02724.9 OAJ02966.1 - 2.5 6.0 6.4 6.9 4.5 4.4 1.7 1 0 0 1 1 1 0 CDC45-like protein FAM178 PF14816.1 OAJ02966.1 - 3.5 6.2 3.3 5.5 5.5 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 SAPS PF04499.10 OAJ02966.1 - 4.7 5.7 5.1 3.8 6.0 2.1 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SNF2_N PF00176.18 OAJ02967.1 - 3.6e-65 219.7 0.2 4.8e-65 219.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ02967.1 - 3.3e-14 52.4 0.0 1.1e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ02967.1 - 1.2e-06 28.4 0.0 6.2e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UBA PF00627.26 OAJ02967.1 - 0.00012 21.7 0.1 0.00037 20.2 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain HHH_3 PF12836.2 OAJ02967.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RXT2_N PF08595.6 OAJ02967.1 - 0.094 12.5 4.6 0.45 10.2 3.2 2.1 1 0 0 1 1 1 0 RXT2-like, N-terminal Las1 PF04031.8 OAJ02967.1 - 0.099 12.3 1.0 0.21 11.2 0.7 1.4 1 0 0 1 1 1 0 Las1-like Pkinase PF00069.20 OAJ02968.1 - 1.1e-64 218.0 0.0 1.5e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02968.1 - 5.4e-29 101.0 0.0 6.8e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02968.1 - 1.6e-06 27.3 0.0 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ02968.1 - 0.081 12.6 0.0 2.5 7.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ02968.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sod_Fe_C PF02777.13 OAJ02969.1 - 2.5e-34 117.3 0.3 5.5e-34 116.1 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 OAJ02969.1 - 3.5e-32 110.5 5.1 7.4e-32 109.4 3.6 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 OAJ02969.1 - 0.0011 18.2 0.1 0.0054 16.0 0.0 2.2 1 1 1 2 2 2 1 AsmA-like C-terminal region DUF1497 PF07384.6 OAJ02969.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1497) Ribosomal_S19 PF00203.16 OAJ02970.1 - 3.4e-24 84.2 0.0 4.4e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SSF PF00474.12 OAJ02971.1 - 2.3e-15 56.1 19.8 2.3e-15 56.1 13.7 2.7 2 1 0 2 2 2 1 Sodium:solute symporter family RNA_pol_A_bac PF01000.21 OAJ02972.1 - 2.8e-28 98.3 0.0 4.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ02972.1 - 8.2e-16 56.8 0.0 1.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 OAJ02973.1 - 2.4e-61 207.1 0.0 2.1e-60 204.0 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02973.1 - 3.3e-33 114.8 0.0 7.8e-27 93.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ02973.1 - 1.9e-06 27.0 0.0 0.0011 18.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAJ02973.1 - 0.00091 19.0 1.8 0.015 15.0 0.0 3.4 3 1 0 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ02973.1 - 0.0032 16.3 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Ribophorin_II PF05817.9 OAJ02973.1 - 0.14 10.3 0.1 0.22 9.7 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II zf-CCHC PF00098.18 OAJ02974.1 - 1.5e-45 151.0 57.0 1.5e-07 30.9 1.7 7.6 8 0 0 8 8 8 7 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ02974.1 - 1.9e-11 43.4 38.3 0.022 14.3 0.2 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ02974.1 - 1.6e-07 30.9 33.4 0.21 11.3 0.9 7.1 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 OAJ02974.1 - 0.0019 17.7 1.5 0.0019 17.7 1.1 7.2 7 0 0 7 7 7 3 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ02974.1 - 0.016 14.6 0.4 0.016 14.6 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle AMP-binding PF00501.23 OAJ02976.1 - 2.5e-92 309.4 0.0 3.3e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ02976.1 - 7.5e-10 39.6 0.0 2.1e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CbtB PF09489.5 OAJ02976.1 - 0.035 14.0 0.4 0.091 12.6 0.3 1.6 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) RPN7 PF10602.4 OAJ02977.1 - 7.8e-45 152.4 0.0 3.9e-44 150.1 0.0 2.0 2 1 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ02977.1 - 1.2e-14 54.5 0.1 3.4e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 PCI domain DUF2461 PF09365.5 OAJ02978.1 - 8.3e-56 188.7 0.0 1.2e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pkinase PF00069.20 OAJ02979.1 - 1.8e-61 207.5 0.0 6.6e-34 117.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ02979.1 - 3.9e-23 81.8 0.0 4.8e-20 71.7 0.0 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase Vps54 PF07928.7 OAJ02980.1 - 3.2e-52 176.2 1.5 3.2e-52 176.2 1.0 1.8 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 OAJ02980.1 - 5e-06 25.6 1.4 5e-06 25.6 0.9 2.4 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) ProRS-C_1 PF09180.6 OAJ02981.1 - 3.7e-24 84.4 1.0 7.7e-24 83.3 0.7 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 OAJ02981.1 - 1.1e-22 80.3 0.0 1.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ02981.1 - 4.2e-15 55.4 0.0 8.7e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain TraC_F_IV PF11130.3 OAJ02981.1 - 0.025 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer ChAPs PF09295.5 OAJ02982.1 - 2e-151 504.2 0.0 2.9e-151 503.7 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 OAJ02982.1 - 6.1e-05 23.2 0.2 0.017 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ02982.1 - 0.0031 17.3 1.3 0.87 9.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ02982.1 - 0.021 14.4 8.3 0.057 13.0 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Palm_thioest PF02089.10 OAJ02983.1 - 1.8e-59 201.0 0.1 2.1e-46 158.1 0.0 2.0 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 OAJ02983.1 - 0.0045 16.5 0.0 0.0063 16.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DCAF15_WD40 PF14939.1 OAJ02983.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Asp_protease_2 PF13650.1 OAJ02984.1 - 0.016 15.6 0.0 0.06 13.8 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 OAJ02984.1 - 0.046 13.5 0.1 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HSF_DNA-bind PF00447.12 OAJ02987.1 - 4.1e-35 120.0 0.1 4.1e-35 120.0 0.0 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 OAJ02987.1 - 2.8e-23 82.0 0.1 6e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain NUDIX PF00293.23 OAJ02989.1 - 5e-16 58.5 0.2 2.7e-15 56.1 0.1 2.4 1 1 1 2 2 2 1 NUDIX domain NDT80_PhoG PF05224.7 OAJ02990.1 - 2.7e-11 43.7 0.1 1.6e-10 41.3 0.1 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Cgr1 PF03879.9 OAJ02991.1 - 3.3e-16 59.3 22.0 3.6e-16 59.2 15.2 1.0 1 0 0 1 1 1 1 Cgr1 family PEARLI-4 PF05278.7 OAJ02991.1 - 0.11 11.9 12.2 0.12 11.6 8.5 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2458 PF10454.4 OAJ02991.1 - 0.51 10.2 7.8 0.64 9.8 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Pilt PF15453.1 OAJ02991.1 - 0.75 9.4 7.4 0.86 9.2 5.1 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions OmpH PF03938.9 OAJ02991.1 - 2 8.3 12.1 2.7 7.9 8.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2500 PF10694.4 OAJ02991.1 - 2.5 8.1 5.0 3 7.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) DUF1675 PF07897.6 OAJ02991.1 - 3.3 7.4 9.1 3.8 7.3 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Transformer PF06495.6 OAJ02991.1 - 3.5 7.4 7.0 3.9 7.3 4.8 1.0 1 0 0 1 1 1 0 Fruit fly transformer protein PAP_central PF04928.12 OAJ02993.1 - 1.9e-94 315.2 0.0 2.5e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 OAJ02993.1 - 3e-40 137.3 0.0 5.5e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 OAJ02993.1 - 4.8e-09 36.4 0.1 1.5e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 OAJ02993.1 - 0.04 11.4 0.0 0.057 10.9 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Atg14 PF10186.4 OAJ02994.1 - 5.7e-14 51.7 15.3 1.1e-07 31.1 0.0 3.7 2 2 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Cys_knot PF00007.17 OAJ02994.1 - 0.003 17.5 0.5 0.0055 16.7 0.4 1.3 1 0 0 1 1 1 1 Cystine-knot domain PTCB-BRCT PF12738.2 OAJ02995.1 - 4.3e-29 100.1 2.5 6.4e-18 64.3 0.1 5.1 4 1 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 OAJ02995.1 - 3.6e-23 81.5 0.0 1.4e-11 44.4 0.0 6.6 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain Grp1_Fun34_YaaH PF01184.14 OAJ02997.1 - 2e-80 269.0 14.1 2.3e-80 268.8 9.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mcp5_PH PF12814.2 OAJ02998.1 - 2.3e-39 134.1 0.0 5.4e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DASH_Dam1 PF08653.5 OAJ02998.1 - 2.8 7.7 2.4 20 5.0 0.6 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 MIP PF00230.15 OAJ02999.1 - 9.4e-42 143.0 12.9 1.2e-41 142.6 9.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF155 PF02582.9 OAJ03000.1 - 1.3e-47 161.9 0.0 1.9e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Daxx PF03344.10 OAJ03000.1 - 2 6.7 26.4 1 7.7 7.4 2.2 2 0 0 2 2 2 0 Daxx Family Metallophos PF00149.23 OAJ03001.1 - 6.1e-44 149.8 0.0 1.9e-43 148.2 0.2 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase UPF0183 PF03676.9 OAJ03002.1 - 6e-17 61.3 0.9 0.0046 15.5 0.1 5.5 5 1 0 5 5 5 5 Uncharacterised protein family (UPF0183) SAM_2 PF07647.12 OAJ03003.1 - 1.8e-09 37.2 0.0 3.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ03003.1 - 5.5e-07 29.6 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Bromodomain PF00439.20 OAJ03004.1 - 4e-14 52.2 0.0 1.4e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Bromodomain TFIIA PF03153.8 OAJ03004.1 - 0.0016 18.4 25.4 0.0016 18.4 17.6 2.7 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 OAJ03004.1 - 1 7.2 19.5 1.7 6.4 13.5 1.3 1 0 0 1 1 1 0 Nop14-like family SCAMP PF04144.8 OAJ03005.1 - 2.6e-43 147.9 3.5 3.1e-43 147.7 2.4 1.0 1 0 0 1 1 1 1 SCAMP family Septin PF00735.13 OAJ03006.1 - 1.2e-110 369.0 0.2 1.5e-110 368.6 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAJ03006.1 - 1.2e-08 34.9 0.0 3e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ03006.1 - 2.1e-05 23.7 0.0 4.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 OAJ03006.1 - 0.00011 22.1 0.3 0.16 11.7 0.1 2.6 1 1 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 OAJ03006.1 - 0.00026 20.5 0.2 0.00062 19.3 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 OAJ03006.1 - 0.00069 18.7 0.6 0.0014 17.7 0.0 1.8 2 0 0 2 2 2 1 AIG1 family AAA_10 PF12846.2 OAJ03006.1 - 0.0013 18.2 0.2 0.0022 17.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 OAJ03006.1 - 0.0023 17.4 0.3 0.026 13.9 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 OAJ03006.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 OAJ03006.1 - 0.014 14.8 0.1 0.027 13.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ03006.1 - 0.02 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 OAJ03006.1 - 0.028 14.5 0.0 0.076 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ03006.1 - 0.04 12.8 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 OAJ03006.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 OAJ03006.1 - 0.066 13.1 0.5 1.3 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 OAJ03006.1 - 0.072 12.9 1.2 0.38 10.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 OAJ03006.1 - 0.081 13.7 1.8 11 6.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 OAJ03006.1 - 0.17 12.1 3.2 0.67 10.2 2.2 1.9 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 OAJ03008.1 - 3.7e-20 71.8 0.0 1.4e-19 69.9 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ03008.1 - 1.1e-08 34.8 10.1 2.3e-08 33.8 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-F_N PF10481.4 OAJ03008.1 - 0.41 9.9 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Cenp-F N-terminal domain Thiolase_N PF00108.18 OAJ03009.1 - 1.5e-82 276.5 1.5 2e-82 276.1 1.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 OAJ03009.1 - 1.2e-48 163.5 0.3 3.7e-48 162.0 0.2 1.9 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 OAJ03009.1 - 3.9e-06 26.5 3.2 5.7e-06 25.9 1.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ank_2 PF12796.2 OAJ03010.1 - 7.2e-17 61.5 0.0 1.2e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ03010.1 - 1.9e-14 53.6 0.1 9.3e-07 29.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ03010.1 - 9.5e-13 47.9 0.3 4.9e-08 32.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ03010.1 - 1.6e-12 46.5 0.7 4.6e-06 26.1 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 OAJ03010.1 - 5.1e-12 44.8 0.0 8.6e-05 22.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat SMC_N PF02463.14 OAJ03011.1 - 1.4e-73 246.7 8.1 7e-73 244.5 5.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ03011.1 - 5.2e-27 94.2 0.0 1.8e-26 92.4 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ03011.1 - 4.2e-15 56.4 5.6 4.2e-07 30.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ03011.1 - 3.7e-05 23.1 0.0 7.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 OAJ03011.1 - 0.00029 18.3 33.4 0.00029 18.3 23.2 4.4 3 2 2 5 5 5 2 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 OAJ03011.1 - 0.0021 17.3 23.8 0.079 12.1 1.6 4.3 3 1 1 4 4 4 3 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 OAJ03011.1 - 0.0056 16.4 2.3 0.0056 16.4 1.6 11.4 9 2 2 12 12 12 2 TATA element modulatory factor 1 DNA binding FTHFS PF01268.14 OAJ03013.1 - 2.8e-259 860.7 0.1 5.7e-259 859.7 0.0 1.5 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 OAJ03013.1 - 8.4e-63 210.2 0.5 8.4e-63 210.2 0.4 2.8 4 0 0 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 OAJ03013.1 - 1e-29 102.9 0.0 2.9e-29 101.4 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Apolipoprotein PF01442.13 OAJ03014.1 - 0.006 16.1 1.1 0.0092 15.5 0.6 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 OAJ03014.1 - 0.0092 15.8 1.0 0.02 14.6 0.5 1.6 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus PSD4 PF07631.6 OAJ03014.1 - 0.065 13.5 1.4 7.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) DUF948 PF06103.6 OAJ03014.1 - 0.23 11.3 2.2 0.47 10.3 1.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3347 PF11827.3 OAJ03014.1 - 0.7 9.8 7.8 0.19 11.7 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Indigoidine_A PF04227.7 OAJ03019.1 - 5.8e-109 363.8 1.0 9.9e-109 363.0 0.7 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 OAJ03019.1 - 1.1e-18 67.3 0.0 3.4e-10 39.5 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase ARGLU PF15346.1 OAJ03019.1 - 0.17 11.6 0.6 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DNA_ligase_A_M PF01068.16 OAJ03020.1 - 1.1e-36 126.0 0.0 9.1e-25 87.2 0.0 3.9 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ03020.1 - 4.4e-33 114.5 0.0 6.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAJ03020.1 - 2.2e-17 63.2 0.1 1.2e-16 60.9 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Trm112p PF03966.11 OAJ03021.1 - 1.2e-18 67.1 0.1 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 OAJ03021.1 - 0.071 12.7 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain SurE PF01975.12 OAJ03022.1 - 9.7e-40 135.9 0.0 1.3e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Polysacc_deac_1 PF01522.16 OAJ03023.1 - 2.7e-23 81.9 0.0 1.6e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase GYF PF02213.11 OAJ03024.1 - 8.5e-18 63.6 0.7 1.7e-17 62.6 0.5 1.4 1 0 0 1 1 1 1 GYF domain Abhydrolase_3 PF07859.8 OAJ03025.1 - 5.9e-30 104.4 0.0 8e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ03025.1 - 9.6e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAJ03025.1 - 0.0019 16.9 0.0 0.0036 16.0 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 OAJ03025.1 - 0.0068 15.6 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Xpo1 PF08389.7 OAJ03026.1 - 1.2e-25 90.1 0.1 3.6e-24 85.3 0.0 3.2 4 1 1 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 OAJ03026.1 - 1.9e-05 24.4 0.1 6.3e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.17 OAJ03026.1 - 0.058 13.4 0.2 1.1 9.5 0.0 3.5 2 0 0 2 2 2 0 HEAT repeat RasGEF_N_2 PF14663.1 OAJ03026.1 - 0.063 13.2 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_EZ PF13513.1 OAJ03026.1 - 6 7.4 14.2 3.9 8.0 0.1 5.9 4 2 2 6 6 6 0 HEAT-like repeat E1-E2_ATPase PF00122.15 OAJ03028.1 - 2.7e-15 56.0 1.9 1.8e-14 53.3 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 OAJ03028.1 - 2.1e-14 54.1 0.1 9.4e-14 52.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ03028.1 - 3.3e-14 53.8 0.4 3.9e-12 47.0 0.3 3.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ03028.1 - 2.8e-12 46.3 0.0 6.5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ03028.1 - 0.0022 17.6 0.1 0.0056 16.2 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Clp1 PF06807.9 OAJ03029.1 - 8.5e-08 32.1 0.0 2.6e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.1 OAJ03029.1 - 0.0013 18.7 0.1 0.0029 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 OAJ03029.1 - 0.0022 17.7 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 OAJ03029.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ03029.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 OAJ03029.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 OAJ03030.1 - 8.3e-25 85.8 18.6 3.6e-08 33.2 0.1 5.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ03030.1 - 1.2e-19 69.4 25.2 4.8e-05 23.4 0.2 5.4 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ03030.1 - 1.1e-10 41.0 23.1 0.0041 17.3 0.2 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ03030.1 - 3.9e-06 26.5 2.2 0.0023 17.7 0.0 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ03030.1 - 4.7e-05 23.3 3.3 0.049 13.7 0.0 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ03030.1 - 0.021 15.0 11.8 1.3 9.2 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type BolA PF01722.13 OAJ03030.1 - 0.14 12.1 1.6 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 BolA-like protein WD40 PF00400.27 OAJ03031.1 - 1.5e-30 103.9 13.0 8.6e-11 41.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF2347 PF09804.4 OAJ03033.1 - 0.92 8.7 7.0 2.5 7.3 4.8 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DEAD PF00270.24 OAJ03034.1 - 6.5e-42 142.8 0.5 1e-41 142.2 0.3 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03034.1 - 1e-23 82.9 0.1 2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 OAJ03034.1 - 0.0011 18.0 0.1 0.0023 17.0 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit CRA_rpt PF07046.6 OAJ03035.1 - 0.017 15.1 1.8 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Cytoplasmic repetitive antigen (CRA) like repeat YbaJ PF10757.4 OAJ03035.1 - 0.054 13.6 0.6 0.6 10.2 0.3 2.4 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ Herpes_IR6 PF06307.7 OAJ03035.1 - 0.22 10.7 0.3 0.42 9.9 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus IR6 protein DUF605 PF04652.11 OAJ03035.1 - 3.6 6.9 9.6 6.1 6.1 6.6 1.3 1 0 0 1 1 1 0 Vta1 like SH3_1 PF00018.23 OAJ03036.1 - 1.6e-13 49.8 0.1 2.4e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ03036.1 - 3.3e-10 39.3 0.0 5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ03036.1 - 3e-08 33.0 0.0 5.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF962 PF06127.6 OAJ03036.1 - 0.0063 16.3 0.4 0.014 15.3 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF962) SH3_3 PF08239.6 OAJ03036.1 - 0.05 13.7 0.2 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Clp1 PF06807.9 OAJ03037.1 - 3.8e-07 30.0 0.0 1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 OAJ03037.1 - 0.0047 16.6 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ03037.1 - 0.0074 16.2 1.9 0.011 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 OAJ03037.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 OAJ03038.1 - 1.1e-12 47.6 4.6 0.034 14.0 0.0 6.5 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03038.1 - 5.9e-06 25.8 12.0 0.03 14.2 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ03038.1 - 0.0002 21.1 22.7 0.012 15.4 0.3 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03038.1 - 0.00032 20.2 0.0 0.37 10.6 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03038.1 - 0.00054 19.5 8.2 0.14 12.0 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ03038.1 - 0.00097 18.6 1.8 1 9.0 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03038.1 - 0.006 16.2 10.3 1.5 8.4 0.0 5.5 4 1 2 6 6 6 2 TPR repeat TPR_4 PF07721.9 OAJ03038.1 - 0.11 12.9 14.4 0.19 12.2 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ03038.1 - 0.13 12.6 12.8 1.6 9.1 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03038.1 - 6.9 7.6 24.0 3.8 8.4 0.0 8.4 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03040.1 - 6.5e-08 31.9 5.1 0.031 14.1 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ03040.1 - 6.6e-05 22.7 4.6 0.017 15.0 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03040.1 - 0.00023 20.7 6.0 0.25 11.0 0.0 4.7 5 1 1 6 6 6 2 TPR repeat TPR_12 PF13424.1 OAJ03040.1 - 0.00081 19.2 12.3 0.041 13.8 0.1 6.5 7 1 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03040.1 - 0.0011 18.5 0.2 0.15 11.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ03040.1 - 0.0015 19.1 6.6 0.13 12.9 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ03040.1 - 0.003 17.1 0.1 1.1 9.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ03040.1 - 0.0058 16.9 4.8 1 9.7 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03040.1 - 0.039 13.7 0.0 0.38 10.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Nop14 PF04147.7 OAJ03040.1 - 1.3 6.8 12.6 2.8 5.7 8.8 1.5 1 0 0 1 1 1 0 Nop14-like family TPR_4 PF07721.9 OAJ03040.1 - 1.4 9.5 7.2 0.2 12.1 0.2 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03040.1 - 5.1 8.0 16.9 3.9 8.3 0.0 5.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2433 PF10360.4 OAJ03041.1 - 6.2e-41 139.8 0.1 1.2e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Polysacc_deac_1 PF01522.16 OAJ03042.1 - 1.9e-22 79.2 0.4 1.7e-21 76.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Sec10 PF07393.6 OAJ03043.1 - 2.6e-239 796.1 0.0 3.5e-239 795.7 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Kri1 PF05178.7 OAJ03043.1 - 0.049 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 KRI1-like family KIAA1328 PF15369.1 OAJ03043.1 - 2.6 7.7 7.2 11 5.7 0.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 zf-DHHC PF01529.15 OAJ03044.1 - 1.1e-17 63.9 0.2 1.1e-17 63.9 0.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase MMTV_SAg PF01054.12 OAJ03044.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen GTP_EFTU PF00009.22 OAJ03045.1 - 4.4e-31 107.7 0.0 2.4e-30 105.3 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAJ03045.1 - 4e-16 58.8 0.2 1.2e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 OAJ03045.1 - 9.3e-10 38.4 0.2 9.3e-10 38.4 0.2 3.9 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ03045.1 - 1.6e-06 28.0 0.0 5.3e-06 26.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 OAJ03045.1 - 0.022 14.9 0.1 0.11 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 OAJ03045.1 - 0.56 10.1 0.0 0.56 10.1 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain ELFV_dehydrog PF00208.16 OAJ03051.1 - 4.4e-73 245.8 1.1 5.3e-73 245.5 0.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 OAJ03051.1 - 1.4e-43 147.6 0.0 3.7e-43 146.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 OAJ03051.1 - 0.074 13.3 0.1 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyoxal_oxid_N PF07250.6 OAJ03052.1 - 4.7e-25 88.0 0.0 2.2e-22 79.3 0.0 4.1 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 OAJ03052.1 - 2.3e-18 66.1 0.1 4.4e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SKG6 PF08693.5 OAJ03052.1 - 0.28 10.5 1.4 0.58 9.5 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKN1 PF03935.10 OAJ03053.1 - 1.4e-142 475.4 1.6 3.5e-82 276.1 0.7 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WGG PF10273.4 OAJ03055.1 - 1e-20 73.6 0.0 1.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TLP-20 PF06088.6 OAJ03055.1 - 0.12 12.0 0.4 0.17 11.5 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RRP7 PF12923.2 OAJ03055.1 - 0.19 11.7 0.3 0.19 11.7 0.2 1.9 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) CobT PF06213.7 OAJ03055.1 - 1.3 8.1 12.0 1.6 7.7 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 OAJ03055.1 - 6.2 4.7 6.3 7.3 4.4 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ03055.1 - 8.8 4.9 13.4 14 4.2 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aconitase PF00330.15 OAJ03056.1 - 1.5e-173 577.5 0.1 3.3e-173 576.4 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ03056.1 - 9.7e-44 148.6 0.0 1.7e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SKN1 PF03935.10 OAJ03057.1 - 2.1e-161 537.4 10.1 1.8e-159 531.1 7.0 2.1 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) D123 PF07065.9 OAJ03058.1 - 3.4e-62 210.2 0.0 1.5e-61 208.1 0.0 2.0 1 1 1 2 2 2 1 D123 Utp14 PF04615.8 OAJ03058.1 - 0.026 12.7 0.8 0.054 11.6 0.6 1.5 1 0 0 1 1 1 0 Utp14 protein CENP-B_dimeris PF09026.5 OAJ03058.1 - 0.48 10.6 27.6 2.5 8.3 2.2 3.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SDA1 PF05285.7 OAJ03058.1 - 0.82 8.8 12.4 0.15 11.2 3.2 2.1 2 0 0 2 2 2 0 SDA1 RRN3 PF05327.6 OAJ03058.1 - 1.3 7.0 4.8 2.5 6.1 3.3 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ofd1_CTDD PF10637.4 OAJ03059.1 - 1.3e-89 299.9 0.0 2.3e-84 282.6 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 OAJ03059.1 - 6.3e-17 61.9 0.0 1.7e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TFIIA PF03153.8 OAJ03059.1 - 0.093 12.6 9.2 0.16 11.8 6.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 OAJ03060.1 - 5.6e-54 183.0 0.6 5.4e-53 179.7 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03060.1 - 1.9e-21 76.3 0.0 1.9e-21 76.3 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase AGTRAP PF06396.6 OAJ03061.1 - 0.13 11.9 1.7 0.32 10.6 1.1 1.7 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Peptidase_M17 PF00883.16 OAJ03062.1 - 7.4e-106 353.5 0.0 1.1e-105 352.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 OAJ03062.1 - 1e-06 28.5 0.1 2.1e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain WD40 PF00400.27 OAJ03062.1 - 0.047 13.5 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat NUC153 PF08159.7 OAJ03063.1 - 3.2e-10 39.3 0.4 6.6e-10 38.3 0.3 1.6 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.7 OAJ03063.1 - 0.1 10.5 20.7 0.15 9.9 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ03063.1 - 1.4 6.8 10.0 2.2 6.2 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 OAJ03063.1 - 1.8 7.7 22.3 0.36 10.0 12.7 1.6 1 1 0 1 1 1 0 SDA1 PIF1 PF05970.9 OAJ03064.1 - 5e-25 88.2 0.0 1.6e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ03064.1 - 4.6e-11 42.6 0.0 2e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ03064.1 - 5e-08 32.5 0.1 1.7e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 OAJ03064.1 - 0.0016 18.4 0.8 0.0076 16.2 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 OAJ03064.1 - 0.0054 16.3 0.8 1.1 8.7 0.0 2.9 2 1 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 OAJ03064.1 - 0.0078 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Torsin PF06309.6 OAJ03064.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Viral_helicase1 PF01443.13 OAJ03064.1 - 0.034 13.6 0.0 3.3 7.1 0.0 3.5 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 OAJ03064.1 - 0.042 13.8 0.0 0.32 11.0 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ03064.1 - 0.055 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 OAJ03064.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase Sigma54_activat PF00158.21 OAJ03064.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RVT_1 PF00078.22 OAJ03066.1 - 7.5e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03066.1 - 7.6e-15 55.0 0.0 1.8e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ03066.1 - 1.5e-06 28.6 0.1 2e-05 24.9 0.0 2.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ03066.1 - 0.00033 20.4 0.0 0.00098 18.9 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ03066.1 - 0.0014 18.5 0.0 0.0042 16.9 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ03067.1 - 1.3e-05 25.1 0.3 2.9e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Phage_integrase PF00589.17 OAJ03068.1 - 0.00011 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ03068.1 - 0.04 14.0 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 OAJ03068.1 - 0.17 12.2 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Pkinase PF00069.20 OAJ03069.1 - 1.6e-60 204.4 0.0 1.4e-58 198.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03069.1 - 3.5e-22 78.7 0.0 2.7e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ03069.1 - 1.2e-05 24.4 0.0 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CDK2AP PF09806.4 OAJ03069.1 - 0.0037 17.5 0.0 0.0045 17.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein APH PF01636.18 OAJ03069.1 - 0.0076 16.0 0.1 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ03069.1 - 0.014 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 OAJ03069.1 - 0.076 11.6 0.4 0.16 10.5 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) SCP2 PF02036.12 OAJ03070.1 - 1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ03070.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal RRM_1 PF00076.17 OAJ03071.1 - 4.1e-24 83.9 0.0 5.7e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03071.1 - 4.5e-20 71.4 0.0 5.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03071.1 - 3.4e-12 46.0 0.0 4.7e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pcc1 PF09341.5 OAJ03071.1 - 0.097 12.7 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Pcc1 DUF605 PF04652.11 OAJ03072.1 - 1.6 8.0 10.6 0.047 13.0 1.2 2.0 2 0 0 2 2 2 0 Vta1 like RVT_1 PF00078.22 OAJ03073.1 - 0.0016 17.8 0.0 0.0061 15.9 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Med17 PF10156.4 OAJ03076.1 - 0.14 10.4 19.0 0.11 10.7 1.8 4.1 3 1 1 4 4 4 0 Subunit 17 of Mediator complex CAP_N PF01213.14 OAJ03077.1 - 0.058 12.6 1.2 0.062 12.5 0.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Prp18 PF02840.10 OAJ03078.1 - 1.3e-57 193.6 0.0 2.1e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 OAJ03078.1 - 1.9e-12 46.2 4.4 4.2e-12 45.0 3.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF2217 PF10265.4 OAJ03078.1 - 0.011 14.6 0.8 0.038 12.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) 4HBT_3 PF13622.1 OAJ03080.1 - 2.9e-30 105.8 2.4 4.2e-30 105.3 1.7 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ03080.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA thioesterase 4HBT PF03061.17 OAJ03081.1 - 0.045 13.8 0.1 0.16 12.0 0.1 1.8 1 1 0 1 1 1 0 Thioesterase superfamily HSP70 PF00012.15 OAJ03082.1 - 8e-51 172.6 0.1 1e-50 172.3 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein Sugar_tr PF00083.19 OAJ03082.1 - 1.1e-39 136.3 10.5 1.5e-39 135.8 7.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter YqhR PF11085.3 OAJ03082.1 - 0.00018 21.0 0.2 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Conserved membrane protein YqhR FGGY_C PF02782.11 OAJ03082.1 - 0.00042 19.9 0.0 0.0022 17.6 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain 4HBT_3 PF13622.1 OAJ03082.1 - 0.0068 16.1 0.1 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_23 PF13489.1 OAJ03083.1 - 5e-22 78.3 0.0 9.7e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ03083.1 - 1.9e-16 60.2 0.0 3.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ03083.1 - 7.2e-14 52.0 0.1 1.9e-13 50.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03083.1 - 3.3e-13 50.1 0.0 6.2e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03083.1 - 7.4e-13 48.3 0.0 6.5e-12 45.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03083.1 - 8.9e-08 32.1 0.8 4e-07 30.0 0.2 2.2 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 OAJ03083.1 - 3.4e-07 29.6 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 OAJ03083.1 - 2.2e-05 23.3 0.0 9.3e-05 21.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.8 OAJ03083.1 - 5.4e-05 22.4 0.0 7.9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 OAJ03083.1 - 0.0001 22.5 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 OAJ03083.1 - 0.004 16.5 0.0 0.049 13.0 0.0 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 OAJ03083.1 - 0.0056 16.0 0.0 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.1 OAJ03083.1 - 0.0077 15.9 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ03083.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 OAJ03083.1 - 0.079 11.8 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase TPMT PF05724.6 OAJ03083.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.7 OAJ03083.1 - 0.11 11.8 0.0 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Metallophos PF00149.23 OAJ03084.1 - 3.9e-19 68.8 0.0 2.9e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 OAJ03084.1 - 6.8e-15 54.9 0.0 1.5e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 OAJ03084.1 - 7.7e-08 31.3 0.0 5.6e-07 28.4 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase fn3 PF00041.16 OAJ03084.1 - 9.1e-05 22.5 1.3 0.0002 21.4 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Metallophos_2 PF12850.2 OAJ03084.1 - 0.0035 17.1 0.0 0.0095 15.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPR_12 PF13424.1 OAJ03085.1 - 1.2e-05 25.1 7.4 3.4 7.6 0.0 6.8 6 2 0 6 6 6 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 OAJ03085.1 - 0.16 11.7 3.3 1.2 8.9 0.2 4.0 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_14 PF13428.1 OAJ03085.1 - 0.61 10.8 41.4 14 6.6 0.1 12.0 11 3 3 14 14 14 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03085.1 - 0.83 9.7 17.1 4.8 7.3 0.1 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Tfb2 PF03849.9 OAJ03086.1 - 3.4e-138 460.2 0.0 4.1e-138 459.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 OAJ03086.1 - 7.8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MULE PF10551.4 OAJ03087.1 - 9.3e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF1681 PF07933.9 OAJ03089.1 - 2.8e-51 173.2 0.0 3.3e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) KGG PF10685.4 OAJ03090.1 - 2.2e-09 37.0 11.8 6e-07 29.2 1.7 4.0 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Pectate_lyase_3 PF12708.2 OAJ03091.1 - 1.5e-68 231.2 6.5 5e-50 170.7 1.9 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 OAJ03091.1 - 5.9e-05 22.4 1.5 0.042 13.3 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 OAJ03091.1 - 0.29 10.8 4.3 0.12 12.1 0.3 2.4 3 0 0 3 3 3 0 Right handed beta helix region PH PF00169.24 OAJ03092.1 - 1.6e-16 60.3 0.0 4.1e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.1 OAJ03092.1 - 1e-13 50.6 0.1 1.9e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ03092.1 - 1.4e-11 43.6 0.4 2.8e-11 42.5 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ03092.1 - 4e-08 32.6 0.0 9.8e-08 31.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 OAJ03092.1 - 6.9e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 OAJ03092.1 - 0.00027 21.0 0.1 0.0006 19.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3104 PF11302.3 OAJ03092.1 - 0.053 12.9 0.1 0.15 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Ste50p-SAM PF09235.5 OAJ03092.1 - 0.088 12.8 0.1 0.3 11.1 0.1 1.9 1 0 0 1 1 1 0 Ste50p, sterile alpha motif KGG PF10685.4 OAJ03093.1 - 1.9e-07 30.8 11.0 6e-07 29.2 1.7 4.0 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif MULE PF10551.4 OAJ03094.1 - 4.3e-08 33.2 0.0 1.2e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ03094.1 - 0.028 12.9 0.0 0.053 12.0 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family FAR1 PF03101.10 OAJ03094.1 - 0.066 13.7 0.2 0.18 12.3 0.2 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain SPX PF03105.14 OAJ03095.1 - 1.2e-48 166.3 0.3 1.6e-48 165.9 0.2 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 OAJ03095.1 - 1.5e-30 106.5 37.0 2e-30 106.0 25.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 OAJ03095.1 - 1.3e-20 73.2 37.6 3.9e-14 51.9 11.7 2.2 1 1 1 2 2 2 2 Citrate transporter Fcf1 PF04900.7 OAJ03096.1 - 7.6e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Fcf1 DUF3776 PF12618.3 OAJ03096.1 - 0.022 15.2 5.2 5 7.7 1.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3776) 4HBT_3 PF13622.1 OAJ03097.1 - 3e-29 102.5 0.8 5.5e-29 101.6 0.5 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HSP70 PF00012.15 OAJ03097.1 - 2e-18 65.6 0.1 2.9e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein Acyl_CoA_thio PF02551.10 OAJ03097.1 - 6.9e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase PH PF00169.24 OAJ03098.1 - 0.00021 21.4 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ03098.1 - 0.0053 17.0 0.4 0.023 14.9 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Sugar_tr PF00083.19 OAJ03099.1 - 2e-118 395.8 25.1 3.4e-117 391.7 17.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ03099.1 - 1.9e-20 72.8 38.5 6.4e-16 58.0 10.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YqhR PF11085.3 OAJ03099.1 - 0.00045 19.7 3.4 0.037 13.5 1.0 2.6 2 0 0 2 2 2 2 Conserved membrane protein YqhR DUF1229 PF06797.6 OAJ03099.1 - 0.0046 15.8 3.6 4.5 5.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1229) KGG PF10685.4 OAJ03100.1 - 4.6e-19 67.8 5.6 8.9e-10 38.2 0.1 2.8 3 1 0 3 3 3 2 Stress-induced bacterial acidophilic repeat motif Trypan_PARP PF05887.6 OAJ03100.1 - 1.1 9.0 7.4 0.47 10.2 0.5 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DEAD PF00270.24 OAJ03101.1 - 3.2e-19 69.0 0.1 1.9e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03101.1 - 3.8e-15 55.4 0.1 1.9e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ03101.1 - 0.00015 21.6 0.0 0.00054 19.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RQC PF09382.5 OAJ03101.1 - 0.0084 15.8 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 RQC domain AAA_22 PF13401.1 OAJ03101.1 - 0.017 15.2 0.1 0.076 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain mRNA_triPase PF02940.10 OAJ03102.1 - 5.8e-47 160.2 0.0 6.8e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain SNase PF00565.12 OAJ03103.1 - 6.7e-45 151.7 0.4 9.6e-17 61.2 0.0 7.1 7 0 0 7 7 7 5 Staphylococcal nuclease homologue TUDOR PF00567.19 OAJ03103.1 - 1.1e-22 80.1 0.0 2.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.7 OAJ03103.1 - 0.0056 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 Agenet domain DUF4537 PF15057.1 OAJ03103.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) SMN PF06003.7 OAJ03103.1 - 0.018 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Tudor-knot PF11717.3 OAJ03103.1 - 0.15 11.7 0.3 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain WD40 PF00400.27 OAJ03104.1 - 9.7e-64 209.1 17.5 5.8e-12 45.0 1.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAJ03104.1 - 1.5e-06 27.6 0.0 0.022 14.2 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.4 OAJ03104.1 - 0.013 14.8 0.2 23 4.4 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature eIF2A PF08662.6 OAJ03104.1 - 0.031 13.9 0.0 5.3 6.7 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 OAJ03104.1 - 0.057 13.1 2.0 2.1 8.0 0.0 3.7 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.7 OAJ03104.1 - 0.12 12.1 4.0 3 7.6 0.1 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.15 OAJ03105.1 - 9.5e-14 51.5 0.0 1.5e-08 34.4 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ03105.1 - 4.1e-12 45.8 0.0 8.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ03105.1 - 9.7e-06 25.6 0.7 5e-05 23.3 0.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF836 PF05768.9 OAJ03106.1 - 2.5e-11 43.6 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 OAJ03106.1 - 0.0015 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain CPSF_A PF03178.10 OAJ03107.1 - 1.1e-67 228.4 0.0 1.7e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region N2227 PF07942.7 OAJ03108.1 - 4.2e-88 294.8 0.0 6.2e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Tho2 PF11262.3 OAJ03108.1 - 0.22 10.5 1.1 0.85 8.6 0.2 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fer2 PF00111.22 OAJ03109.1 - 8.9e-10 38.1 0.5 1.3e-09 37.6 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Hus1 PF04005.7 OAJ03110.1 - 1.6e-66 224.2 0.0 2.8e-66 223.4 0.0 1.4 1 1 0 1 1 1 1 Hus1-like protein Myc_N PF01056.13 OAJ03115.1 - 0.00016 20.9 0.3 0.00023 20.4 0.2 1.3 1 0 0 1 1 1 1 Myc amino-terminal region DUF4632 PF15451.1 OAJ03115.1 - 0.35 10.8 2.3 0.28 11.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) CDC45 PF02724.9 OAJ03115.1 - 1.6 6.6 4.6 2 6.3 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TMEM171 PF15471.1 OAJ03115.1 - 2.4 6.8 5.6 0.24 10.1 0.6 1.6 2 0 0 2 2 2 0 Transmembrane protein family 171 Peptidase_C12 PF01088.16 OAJ03116.1 - 2.2e-61 206.7 0.0 2.5e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Sec63 PF02889.11 OAJ03117.1 - 1.1e-33 116.7 0.0 2.1e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 OAJ03117.1 - 4.2e-16 58.4 0.2 8.9e-16 57.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain PX PF00787.19 OAJ03118.1 - 2.8e-24 85.0 0.1 5.2e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 PX domain Med15 PF09606.5 OAJ03118.1 - 2.2 6.4 50.8 3.1 5.8 35.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 OAJ03118.1 - 2.6 6.1 58.9 4.1 5.5 40.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCM PF00493.18 OAJ03119.1 - 1.1e-128 428.7 0.0 1.5e-128 428.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ03119.1 - 1.4e-23 83.6 0.1 3.7e-23 82.3 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 OAJ03119.1 - 9.4e-08 31.4 0.0 1.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ03119.1 - 0.0036 16.8 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ03119.1 - 0.0055 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ03119.1 - 0.054 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP1_TM PF14812.1 OAJ03119.1 - 1.5 9.1 6.8 0.46 10.8 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sds3 PF08598.6 OAJ03120.1 - 4.3e-08 32.9 9.8 4.3e-08 32.9 6.8 2.4 1 1 1 2 2 2 1 Sds3-like PAT1 PF09770.4 OAJ03120.1 - 1.1 7.3 29.7 1.7 6.8 20.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_3 PF01764.20 OAJ03122.1 - 6e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Nop14 PF04147.7 OAJ03122.1 - 0.0042 15.0 15.3 0.0066 14.4 10.6 1.2 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.7 OAJ03122.1 - 0.33 10.1 7.0 27 3.8 7.3 2.2 2 0 0 2 2 2 0 NOA36 protein Ycf1 PF05758.7 OAJ03122.1 - 0.94 7.1 4.5 2 6.0 3.2 1.4 1 1 0 1 1 1 0 Ycf1 YL1 PF05764.8 OAJ03122.1 - 1.5 8.3 23.7 0.61 9.6 2.9 2.5 2 0 0 2 2 2 0 YL1 nuclear protein AvrE PF11725.3 OAJ03122.1 - 3.9 4.3 13.9 5.8 3.7 9.7 1.1 1 0 0 1 1 1 0 Pathogenicity factor Pex24p PF06398.6 OAJ03123.1 - 2.7e-31 108.6 0.0 1.8e-24 86.2 0.0 2.3 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Nipped-B_C PF12830.2 OAJ03124.1 - 2.6e-46 157.6 0.9 1.1e-45 155.5 0.6 2.2 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 OAJ03124.1 - 5.5e-10 38.9 0.1 8.1e-09 35.2 0.1 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 OAJ03124.1 - 0.0018 18.7 4.6 0.22 12.0 1.2 4.5 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.2 OAJ03124.1 - 0.1 12.4 0.8 0.96 9.2 0.1 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF202 PF02656.10 OAJ03125.1 - 4.2e-08 33.2 7.8 1.1e-07 31.9 2.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Sld5 PF05916.6 OAJ03125.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.4 1 1 0 1 1 1 0 GINS complex protein SecE PF00584.15 OAJ03125.1 - 2.3 7.8 6.3 1.6 8.4 2.2 2.1 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex EVE PF01878.13 OAJ03126.1 - 9.4e-41 139.1 0.0 2e-40 138.0 0.0 1.6 1 0 0 1 1 1 1 EVE domain Lactamase_B_2 PF12706.2 OAJ03126.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TFIIA PF03153.8 OAJ03127.1 - 0.00013 22.0 33.1 0.00013 22.0 22.9 2.9 2 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit DUF3432 PF11914.3 OAJ03127.1 - 0.88 9.6 9.9 0.24 11.4 2.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Utp12 PF04003.7 OAJ03131.1 - 6.3e-09 35.7 2.7 2.7e-08 33.6 1.9 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family Cut8_C PF08559.5 OAJ03132.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Cut8 six-helix bundle HEAT_EZ PF13513.1 OAJ03132.1 - 0.78 10.3 3.3 24 5.5 0.3 3.2 3 0 0 3 3 3 0 HEAT-like repeat PRP3 PF08572.5 OAJ03133.1 - 5.3e-62 209.1 9.0 8.6e-62 208.4 6.2 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 OAJ03133.1 - 7.8e-25 87.0 0.0 1.7e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) MmlI PF09448.5 OAJ03133.1 - 0.031 14.0 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase TRAP-gamma PF07074.7 OAJ03133.1 - 0.54 9.7 2.1 1 8.8 1.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Peptidase_S26 PF10502.4 OAJ03134.1 - 1.2e-07 31.3 0.0 1.1e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 OAJ03134.1 - 3.6e-05 23.3 0.0 0.00018 21.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Pkinase PF00069.20 OAJ03135.1 - 6.6e-64 215.5 0.0 8.1e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03135.1 - 4.4e-38 130.8 0.0 1.1e-34 119.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ03135.1 - 0.00045 19.2 0.0 0.00094 18.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ03135.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 OAJ03135.1 - 0.099 11.9 0.0 0.31 10.3 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 OAJ03135.1 - 0.12 11.1 0.1 0.25 10.1 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 ERG4_ERG24 PF01222.12 OAJ03136.1 - 2e-122 408.8 20.4 2.4e-122 408.5 14.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family LSM PF01423.17 OAJ03137.1 - 1.9e-14 52.9 0.0 2.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Mito_carr PF00153.22 OAJ03138.1 - 5.1e-73 240.8 9.2 6.8e-24 83.4 0.1 4.8 4 1 0 4 4 4 4 Mitochondrial carrier protein Pro_isomerase PF00160.16 OAJ03139.1 - 2.7e-48 164.0 0.0 3.4e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Mid2 PF04478.7 OAJ03140.1 - 0.02 14.2 0.2 0.038 13.3 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DAP10 PF07213.6 OAJ03140.1 - 0.086 12.6 0.4 0.26 11.0 0.3 1.7 1 1 0 1 1 1 0 DAP10 membrane protein TH1 PF04858.8 OAJ03140.1 - 0.11 10.6 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 TH1 protein DUF3545 PF12065.3 OAJ03141.1 - 0.057 13.1 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Toxin_56 PF15534.1 OAJ03141.1 - 0.06 13.8 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 Putative toxin 56 DUF4098 PF13345.1 OAJ03141.1 - 0.38 10.7 7.8 0.61 10.0 5.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4098) HAD_2 PF13419.1 OAJ03142.1 - 5.9e-13 49.4 0.0 2e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ03142.1 - 1.7e-05 24.4 0.1 5e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 OAJ03142.1 - 0.00048 20.5 0.0 0.0036 17.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 OAJ03143.1 - 3.8e-54 184.0 0.0 8.9e-54 182.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ03143.1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase TT_ORF2 PF02957.10 OAJ03145.1 - 0.35 11.5 6.5 11 6.6 0.3 3.0 2 0 0 2 2 2 0 TT viral ORF2 RNA_pol_Rpb1_5 PF04998.12 OAJ03146.1 - 2.2e-92 309.2 0.2 3.9e-92 308.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 OAJ03146.1 - 8.5e-89 298.1 0.0 1.3e-88 297.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 OAJ03146.1 - 2.1e-63 213.2 0.0 4.1e-63 212.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 OAJ03146.1 - 2.1e-38 131.5 0.0 5.2e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 OAJ03146.1 - 7.3e-28 96.4 0.0 1.9e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Melittin PF01372.12 OAJ03146.1 - 0.18 11.1 1.0 7.4 6.0 0.3 2.4 2 0 0 2 2 2 0 Melittin AAA PF00004.24 OAJ03147.1 - 9.2e-41 139.1 0.0 1.8e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 OAJ03147.1 - 1.4e-26 92.1 0.3 1.2e-25 89.1 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 OAJ03147.1 - 7.7e-21 73.7 5.8 7.7e-21 73.7 4.0 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 OAJ03147.1 - 3.1e-05 24.7 0.4 0.00026 21.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ03147.1 - 3.5e-05 23.9 0.5 0.005 16.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ03147.1 - 7.8e-05 22.1 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 OAJ03147.1 - 9.2e-05 22.3 0.1 0.00028 20.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 OAJ03147.1 - 0.00014 21.6 0.0 0.00049 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 OAJ03147.1 - 0.00014 20.7 0.4 0.00024 19.9 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 OAJ03147.1 - 0.0002 20.4 0.0 0.00037 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ03147.1 - 0.00025 20.9 0.2 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ03147.1 - 0.00067 19.6 0.2 0.0094 15.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 OAJ03147.1 - 0.00076 19.6 0.0 0.024 14.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 OAJ03147.1 - 0.00085 18.7 0.2 0.24 10.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ03147.1 - 0.0034 16.3 0.0 0.0063 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 OAJ03147.1 - 0.0034 17.3 0.0 0.0088 15.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 OAJ03147.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAJ03147.1 - 0.03 13.4 0.1 0.58 9.2 0.0 2.5 1 1 1 2 2 2 0 Zeta toxin KaiC PF06745.8 OAJ03147.1 - 0.033 13.2 0.0 4.5 6.3 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 OAJ03147.1 - 0.036 13.6 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 OAJ03147.1 - 0.063 12.9 0.7 2.1 7.9 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 OAJ03147.1 - 0.066 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Sigma54_activat PF00158.21 OAJ03147.1 - 0.077 12.4 0.0 0.53 9.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 OAJ03147.1 - 0.081 12.1 0.8 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 OAJ03147.1 - 0.12 12.0 0.0 0.79 9.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_10 PF12846.2 OAJ03147.1 - 0.12 11.7 0.9 0.84 9.0 0.1 2.4 3 0 0 3 3 3 0 AAA-like domain AAA_18 PF13238.1 OAJ03147.1 - 0.61 10.3 0.0 0.61 10.3 0.0 2.5 3 1 0 3 3 2 0 AAA domain PEMT PF04191.8 OAJ03148.1 - 1.1e-20 73.6 1.2 1.1e-20 73.6 0.8 2.1 3 0 0 3 3 3 1 Phospholipid methyltransferase LRR_6 PF13516.1 OAJ03152.1 - 0.0012 18.7 10.4 8.3 6.8 0.0 8.0 10 0 0 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 OAJ03152.1 - 0.032 14.3 0.2 84 4.0 0.0 4.9 4 0 0 4 4 4 0 Leucine rich repeat ACT PF01842.20 OAJ03152.1 - 0.5 9.9 3.1 2.6 7.6 0.2 3.0 3 0 0 3 3 3 0 ACT domain LRR_1 PF00560.28 OAJ03152.1 - 2.4 8.5 9.4 10 6.6 0.1 5.8 6 1 0 6 6 6 0 Leucine Rich Repeat Ribosomal_S21 PF01165.15 OAJ03153.1 - 1.1e-11 43.9 7.1 1.1e-11 43.9 4.9 1.5 2 0 0 2 2 2 1 Ribosomal protein S21 Put_Phosphatase PF06888.7 OAJ03154.1 - 4.7e-50 169.9 0.0 5.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase vATP-synt_AC39 PF01992.11 OAJ03155.1 - 1.4e-97 326.9 0.0 1.5e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DNase-RNase PF02577.9 OAJ03155.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Bifunctional nuclease FAD_binding_1 PF00667.15 OAJ03156.1 - 3.7e-52 176.9 0.0 5.4e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 OAJ03156.1 - 1.2e-07 32.2 0.1 2e-06 28.3 0.0 2.6 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain POR PF01558.13 OAJ03156.1 - 6e-05 23.0 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Alkyl_sulf_C PF14864.1 OAJ03156.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal AP_endonuc_2 PF01261.19 OAJ03157.1 - 1.5e-14 53.7 0.1 0.00013 21.3 0.0 3.2 2 1 1 3 3 3 3 Xylose isomerase-like TIM barrel DMA PF03474.9 OAJ03157.1 - 0.067 13.0 0.1 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 DMRTA motif LSM PF01423.17 OAJ03158.1 - 3.7e-12 45.5 0.1 4.8e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ03158.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Aminotran_1_2 PF00155.16 OAJ03159.1 - 6.4e-45 153.6 0.0 5.5e-44 150.5 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 OAJ03159.1 - 0.012 14.1 0.0 0.029 12.9 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 OAJ03159.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 OAJ03159.1 - 0.028 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V SAMP PF05924.6 OAJ03159.1 - 0.031 13.4 0.3 0.16 11.1 0.1 2.3 2 0 0 2 2 2 0 SAMP Motif DUF3827 PF12877.2 OAJ03159.1 - 4.4 5.2 5.8 6.2 4.7 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ribosomal_S8 PF00410.14 OAJ03160.1 - 2.4e-15 56.5 0.0 2.9e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L16 PF00252.13 OAJ03161.1 - 8.2e-31 106.5 0.0 1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF695 PF05117.7 OAJ03162.1 - 0.067 13.1 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF695) SRP40_C PF05022.7 OAJ03163.1 - 1.4e-30 105.5 3.5 4.6e-30 103.9 2.5 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Sld5 PF05916.6 OAJ03164.1 - 2.3e-05 24.6 0.0 3.4e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 GINS complex protein DUF410 PF04190.8 OAJ03165.1 - 2.9e-27 95.8 0.0 6e-19 68.6 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF410) Epimerase PF01370.16 OAJ03166.1 - 4.4e-42 144.1 0.0 7.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 OAJ03166.1 - 3.2e-10 39.3 0.1 2.3e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 OAJ03166.1 - 7.9e-10 38.0 0.0 8.9e-06 24.8 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 OAJ03166.1 - 2.1e-09 36.4 0.0 3.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ03166.1 - 1e-05 24.6 0.0 0.0018 17.2 0.0 3.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 OAJ03166.1 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ03166.1 - 0.033 14.1 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Asp PF00026.18 OAJ03167.1 - 4.2e-71 239.8 0.6 5.9e-71 239.3 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ03167.1 - 1.2e-07 31.8 0.1 3.3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal A_deaminase PF00962.17 OAJ03168.1 - 4.4e-45 154.0 0.0 1.3e-44 152.4 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 OAJ03168.1 - 9.4e-08 31.9 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Complex1_LYR_2 PF13233.1 OAJ03169.1 - 1.4e-11 44.7 0.0 2.5e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Herpes_BLLF1 PF05109.8 OAJ03169.1 - 0.19 9.6 7.8 0.25 9.2 5.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Epimerase PF01370.16 OAJ03170.1 - 2e-17 63.4 0.3 5.6e-17 61.9 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ03170.1 - 1.7e-16 59.7 0.0 7.8e-16 57.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 OAJ03170.1 - 2.3e-14 53.7 0.1 6.9e-14 52.2 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ03170.1 - 4e-11 42.3 0.0 8.8e-10 37.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAJ03170.1 - 4.4e-07 29.3 0.2 1.1e-06 28.0 0.2 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 OAJ03170.1 - 4.9e-06 25.6 0.0 1.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 OAJ03170.1 - 0.0041 16.8 0.8 0.2 11.3 0.5 2.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 OAJ03170.1 - 0.017 15.0 6.1 0.017 15.0 0.5 3.2 3 1 0 3 3 3 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 OAJ03170.1 - 0.027 14.7 0.1 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 OAJ03170.1 - 0.027 13.3 0.1 0.11 11.4 0.1 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain UFD1 PF03152.9 OAJ03171.1 - 6.4e-65 217.5 0.0 8.2e-65 217.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 OAJ03171.1 - 0.083 12.5 1.5 0.48 10.1 0.0 2.6 2 1 1 3 3 3 0 Cell division protein 48 (CDC48), domain 2 3Beta_HSD PF01073.14 OAJ03172.1 - 9.7e-18 63.8 0.0 6.9e-17 61.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ03172.1 - 4.5e-15 55.7 0.1 8.1e-15 54.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ03172.1 - 1.6e-13 51.0 0.2 3.8e-13 49.8 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ03172.1 - 3.7e-10 39.1 0.2 4e-09 35.7 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 OAJ03172.1 - 1.6e-07 30.8 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 OAJ03172.1 - 1.7e-05 24.7 0.3 1.7e-05 24.7 0.2 2.1 3 1 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 OAJ03172.1 - 0.00013 20.9 0.1 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 OAJ03172.1 - 0.00096 18.8 0.4 0.014 15.0 0.3 2.2 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 OAJ03172.1 - 0.0014 19.0 0.0 0.004 17.5 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAJ03172.1 - 0.0081 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Fox-1_C PF12414.3 OAJ03173.1 - 0.047 14.1 0.7 0.24 11.8 0.1 2.5 2 0 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal UDPGT PF00201.13 OAJ03174.1 - 1e-08 34.2 0.0 3e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 OAJ03174.1 - 0.00013 21.7 0.3 0.00026 20.7 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_2 PF13477.1 OAJ03174.1 - 0.034 13.9 0.0 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like Mtc PF03820.12 OAJ03175.1 - 2e-87 292.6 0.0 2.4e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier zf-DNL PF05180.7 OAJ03176.1 - 6.9e-29 99.3 0.1 1.1e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger PRP1_N PF06424.7 OAJ03177.1 - 7.5e-45 152.5 3.2 7.5e-45 152.5 2.2 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 OAJ03177.1 - 1.2e-26 90.7 22.8 0.025 15.1 0.1 13.9 7 5 7 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ03177.1 - 3.6e-20 72.0 5.5 0.016 15.5 0.0 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ03177.1 - 1.6e-19 69.9 12.3 0.0024 18.5 0.3 7.2 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03177.1 - 1.9e-09 37.0 0.2 0.0027 17.3 0.0 7.0 7 2 3 10 10 10 1 TPR repeat TPR_2 PF07719.12 OAJ03177.1 - 5.5e-07 29.0 0.6 35 4.6 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ03177.1 - 4.9e-05 23.1 0.8 0.29 10.9 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 OAJ03177.1 - 0.00093 19.0 0.0 0.56 9.8 0.0 4.5 6 1 0 6 6 6 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 OAJ03177.1 - 0.0059 16.9 3.6 15 6.3 0.0 7.0 6 1 0 6 6 6 0 Tetratricopeptide repeat FAT PF02259.18 OAJ03177.1 - 0.014 14.3 11.0 1.8 7.4 0.2 4.1 1 1 0 2 2 2 0 FAT domain TPR_12 PF13424.1 OAJ03177.1 - 1.8 8.5 6.6 81 3.2 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Lum_binding PF00677.12 OAJ03178.1 - 5.9e-28 96.5 0.0 9e-19 67.1 0.1 3.7 3 1 0 3 3 3 3 Lumazine binding domain Herpes_gI PF01688.12 OAJ03178.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I DUF3419 PF11899.3 OAJ03180.1 - 5.9e-138 459.7 0.1 7.9e-138 459.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 OAJ03180.1 - 3.3e-09 36.6 0.0 4.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03180.1 - 1.1e-08 34.8 0.0 2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ03180.1 - 1.3e-06 28.7 0.0 0.00035 20.9 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ03180.1 - 1.4e-06 28.6 0.0 4.3e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ03180.1 - 2.3e-06 26.9 0.0 0.00035 19.7 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 OAJ03180.1 - 3.7e-06 27.2 0.0 1.8e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03180.1 - 2.9e-05 24.6 0.0 0.00012 22.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03180.1 - 0.0016 18.4 0.1 0.075 13.0 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 OAJ03180.1 - 0.044 12.8 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase COesterase PF00135.23 OAJ03182.1 - 1.9e-104 350.3 0.1 2.5e-104 349.8 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ03182.1 - 4e-06 26.5 0.1 5.7e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cytomega_UL20A PF05984.7 OAJ03182.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Ribosomal_L30_N PF08079.7 OAJ03183.1 - 4.7e-26 90.5 17.8 9.5e-26 89.6 12.3 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 OAJ03183.1 - 1.1e-17 63.3 0.8 3.1e-17 61.8 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.6 OAJ03183.1 - 0.076 13.1 0.6 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus NOB1_Zn_bind PF08772.6 OAJ03184.1 - 4.4e-27 93.7 2.5 1.2e-26 92.3 1.7 1.8 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like BTV_NS2 PF04514.7 OAJ03184.1 - 0.048 12.5 2.2 0.078 11.8 1.5 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-ribbon_3 PF13248.1 OAJ03184.1 - 1.6 8.0 4.9 3.7 6.8 3.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain AF1Q PF15017.1 OAJ03184.1 - 2.5 8.0 12.9 20 5.1 8.9 2.4 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator Rad21_Rec8_N PF04825.8 OAJ03185.1 - 1.3e-42 144.2 0.1 2.2e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 OAJ03185.1 - 1e-14 53.4 0.0 2.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 OAJ03185.1 - 0.0032 17.1 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein FliG_C PF01706.11 OAJ03185.1 - 0.0081 16.1 0.2 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 FliG C-terminal domain Ham1p_like PF01725.11 OAJ03186.1 - 5.1e-46 156.4 0.0 6.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ham1 family 3HCDH_N PF02737.13 OAJ03187.1 - 1.1e-41 142.5 0.4 5.9e-41 140.0 0.3 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 OAJ03187.1 - 5.6e-36 122.8 0.1 4.3e-35 120.0 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.19 OAJ03187.1 - 0.13 11.0 0.2 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Proteasome PF00227.21 OAJ03188.1 - 2.1e-58 196.7 0.1 2.6e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ03188.1 - 2.5e-07 29.8 4.4 5.9e-06 25.4 0.1 2.4 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature FtsZ_C PF12327.3 OAJ03188.1 - 0.094 12.8 0.5 0.19 11.7 0.4 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain GCR1_C PF12550.3 OAJ03194.1 - 1.1e-15 57.1 0.0 2.6e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DNA_ligase_OB_2 PF14743.1 OAJ03196.1 - 5.1e-27 93.3 0.4 8e-27 92.7 0.2 1.3 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 OAJ03196.1 - 3.1e-14 52.8 0.0 5.1e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain mRNA_cap_enzyme PF01331.14 OAJ03196.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain SWIM PF04434.12 OAJ03196.1 - 0.073 12.5 0.7 0.17 11.4 0.5 1.6 1 0 0 1 1 1 0 SWIM zinc finger FHA PF00498.21 OAJ03197.1 - 3.9e-14 52.4 0.0 7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 OAJ03197.1 - 9.6 4.5 12.0 12 4.1 8.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Transp_cyt_pur PF02133.10 OAJ03198.1 - 1.9e-127 425.5 43.3 5.3e-121 404.2 23.3 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Meth_synt_2 PF01717.13 OAJ03199.1 - 1e-142 474.9 0.0 8.5e-136 452.1 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 OAJ03199.1 - 6.1e-122 406.7 0.0 9.6e-109 363.3 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain SHOCT PF09851.4 OAJ03199.1 - 0.0016 17.8 0.2 0.0042 16.5 0.2 1.8 1 0 0 1 1 1 1 Short C-terminal domain Methyltransf_11 PF08241.7 OAJ03200.1 - 5.7e-11 42.7 0.0 2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03200.1 - 4.3e-09 36.9 0.0 1.2e-08 35.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ03200.1 - 4.8e-07 30.1 0.0 1.3e-05 25.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03200.1 - 5.1e-06 26.5 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03200.1 - 7.4e-06 25.7 0.0 4.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03200.1 - 3e-05 23.6 0.0 0.00085 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ03200.1 - 5e-05 23.6 0.0 0.00022 21.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 OAJ03200.1 - 0.066 11.9 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) UQ_con PF00179.21 OAJ03202.1 - 6.6e-40 135.7 0.0 8.2e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 OAJ03202.1 - 7.8e-22 76.6 0.1 1.2e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 OAJ03202.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_2 PF08587.6 OAJ03202.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF1421 PF07223.6 OAJ03202.1 - 0.061 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Kelch_6 PF13964.1 OAJ03203.1 - 2.2e-12 46.5 1.0 0.034 14.3 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 OAJ03203.1 - 5e-11 42.2 3.8 0.0024 17.6 0.8 5.1 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ03203.1 - 2.9e-09 36.8 4.9 0.00023 21.2 0.0 6.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 OAJ03203.1 - 3.6e-08 33.1 0.2 0.0001 22.1 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 OAJ03203.1 - 7.7e-08 31.7 0.0 0.00089 18.7 0.0 3.6 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 OAJ03203.1 - 4.6e-07 29.3 0.3 0.0014 18.3 0.0 3.8 3 0 0 3 3 3 2 Kelch motif DUF3712 PF12505.3 OAJ03204.1 - 4.9e-103 339.9 53.2 2.2e-22 79.3 2.5 8.2 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 OAJ03204.1 - 1.4e-08 34.9 16.7 0.0014 18.9 0.0 8.2 7 0 0 7 7 7 2 Late embryogenesis abundant protein adh_short PF00106.20 OAJ03205.1 - 3.1e-18 66.2 0.0 4.6e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ03205.1 - 6.1e-11 42.3 0.0 8.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ03205.1 - 3e-08 33.3 0.1 6.5e-08 32.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 OAJ03205.1 - 7e-06 25.1 0.0 9.2e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 OAJ03205.1 - 0.00097 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ03205.1 - 0.0095 15.6 0.7 0.026 14.1 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 OAJ03205.1 - 0.011 15.7 0.0 0.064 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.12 OAJ03205.1 - 0.023 15.1 0.1 0.078 13.4 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 OAJ03205.1 - 0.023 14.7 0.6 0.27 11.2 0.4 2.2 1 1 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 OAJ03205.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1776 PF08643.5 OAJ03205.1 - 0.07 12.2 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) VP4_haemagglut PF00426.13 OAJ03205.1 - 0.1 10.5 0.9 0.14 10.0 0.6 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) 3Beta_HSD PF01073.14 OAJ03205.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPPC10 PF12584.3 OAJ03207.1 - 1.9e-18 66.3 0.0 3.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 zf-UBR PF02207.15 OAJ03208.1 - 0.29 10.8 9.0 0.54 10.0 6.2 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn-ribbon_8 PF09723.5 OAJ03208.1 - 3 7.8 6.6 15 5.6 0.0 2.5 2 1 0 2 2 2 0 Zinc ribbon domain Aldo_ket_red PF00248.16 OAJ03209.1 - 2.3e-14 52.8 0.0 4.1e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family Gpi1 PF05024.10 OAJ03210.1 - 2.8e-42 144.5 0.5 5.2e-42 143.6 0.4 1.5 1 1 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Chromate_transp PF02417.10 OAJ03211.1 - 0.77 9.3 18.0 0.041 13.4 4.4 2.7 2 1 0 2 2 2 0 Chromate transporter DUF1422 PF07226.6 OAJ03211.1 - 0.97 9.1 10.9 1.3 8.8 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1422) DUF1129 PF06570.6 OAJ03211.1 - 1.3 8.3 3.7 0.49 9.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) NfeD PF01957.13 OAJ03211.1 - 7.2 6.7 16.0 1.4 9.0 1.1 3.4 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding ELFV_dehydrog PF00208.16 OAJ03212.1 - 1.6e-46 158.9 0.0 2.4e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 OAJ03212.1 - 1.4e-20 72.5 0.1 1.3e-14 52.7 0.0 2.5 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 OAJ03212.1 - 0.0035 16.8 0.0 0.0089 15.6 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain CTX_RstB PF07459.6 OAJ03213.1 - 0.0095 15.8 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 CTX phage RstB protein AMP-binding PF00501.23 OAJ03214.1 - 3.8e-177 588.8 0.0 1.7e-89 300.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 OAJ03214.1 - 9.3e-41 139.6 0.0 1.4e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 OAJ03214.1 - 5.3e-11 43.3 0.1 1.1e-07 32.6 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 OAJ03214.1 - 6.7e-10 39.0 0.1 1.8e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Bactofilin PF04519.8 OAJ03214.1 - 0.087 12.8 1.9 14 5.8 0.1 2.5 2 0 0 2 2 2 0 Polymer-forming cytoskeletal Pollen_Ole_e_I PF01190.12 OAJ03215.1 - 0.033 14.0 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 Pollen proteins Ole e I like Asparaginase PF00710.15 OAJ03216.1 - 6.8e-63 212.4 0.0 8.2e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Asparaginase FMO-like PF00743.14 OAJ03217.1 - 2.9e-32 111.5 0.0 3.2e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ03217.1 - 1.4e-14 54.6 0.0 4.8e-14 52.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ03217.1 - 4.9e-08 32.8 0.4 0.058 13.1 0.1 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ03217.1 - 1.6e-07 31.3 0.0 2.1e-06 27.7 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ03217.1 - 1.7e-07 30.4 0.2 1.3e-05 24.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAJ03217.1 - 0.00021 21.2 0.1 0.00044 20.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 OAJ03217.1 - 0.055 12.5 0.0 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 OAJ03217.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ABC_tran PF00005.22 OAJ03219.1 - 7.6e-46 155.8 0.0 2.6e-28 99.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 OAJ03219.1 - 3.5e-36 125.0 34.1 1.6e-19 70.3 11.1 3.0 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ03219.1 - 6.9e-12 45.0 0.7 1e-05 24.8 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 OAJ03219.1 - 5.1e-08 33.2 0.1 0.65 9.9 0.0 4.2 2 2 1 3 3 3 3 AAA domain AAA_29 PF13555.1 OAJ03219.1 - 3e-07 29.8 0.2 0.015 14.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ03219.1 - 4.3e-07 30.1 3.2 1.5e-05 25.0 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.4 OAJ03219.1 - 1.6e-05 23.7 1.8 0.026 13.1 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Miro PF08477.8 OAJ03219.1 - 5.1e-05 23.7 0.9 0.12 12.8 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 OAJ03219.1 - 5.7e-05 22.6 0.1 0.0013 18.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAJ03219.1 - 0.00013 21.9 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 OAJ03219.1 - 0.00031 20.6 0.5 0.036 13.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.1 OAJ03219.1 - 0.00078 19.8 0.0 0.83 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ03219.1 - 0.00085 18.7 3.0 0.14 11.5 0.1 3.1 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 OAJ03219.1 - 0.0013 18.5 1.1 1.3 9.0 0.2 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 OAJ03219.1 - 0.0015 18.7 0.6 0.25 11.4 0.3 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ03219.1 - 0.0028 17.1 0.2 0.45 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 OAJ03219.1 - 0.0057 15.8 0.3 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAJ03219.1 - 0.009 15.8 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ03219.1 - 0.018 15.3 0.0 0.43 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 OAJ03219.1 - 0.022 13.6 0.9 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.1 OAJ03219.1 - 0.027 15.3 0.0 0.87 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 OAJ03219.1 - 0.051 13.2 0.2 1 9.0 0.2 2.6 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 OAJ03219.1 - 0.054 12.9 2.4 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 OAJ03219.1 - 0.056 13.1 1.8 2.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 OAJ03219.1 - 0.069 11.7 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF87 PF01935.12 OAJ03219.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 OAJ03219.1 - 0.1 12.3 0.5 15 5.1 0.1 2.5 2 1 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 OAJ03219.1 - 0.15 10.6 0.5 0.28 9.7 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain GTP_EFTU PF00009.22 OAJ03219.1 - 0.18 11.2 0.4 24 4.3 0.1 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 OAJ03219.1 - 0.83 8.6 0.0 17 4.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 OAJ03219.1 - 1.6 7.4 2.4 19 3.9 0.6 2.9 2 1 0 2 2 2 0 NB-ARC domain FMO-like PF00743.14 OAJ03220.1 - 1.3e-32 112.7 0.0 3.1e-19 68.5 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ03220.1 - 1.8e-13 51.0 0.0 1.5e-12 47.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ03220.1 - 3.8e-08 33.2 0.0 3.4e-06 26.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ03220.1 - 6.7e-07 29.3 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ03220.1 - 3.2e-05 23.0 0.4 0.0033 16.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 OAJ03220.1 - 0.00021 21.2 0.0 0.00047 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 OAJ03220.1 - 0.0024 17.0 0.0 0.34 9.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 OAJ03220.1 - 0.19 10.8 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 OAJ03220.1 - 0.2 11.1 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain ADH_zinc_N PF00107.21 OAJ03224.1 - 9.6e-20 70.4 0.0 1.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ03224.1 - 3.3e-07 31.2 0.0 7.6e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 OAJ03224.1 - 0.057 12.9 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.1 OAJ03224.1 - 0.062 13.3 0.4 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 OAJ03224.1 - 0.069 12.5 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SpoIIE PF07228.7 OAJ03226.1 - 6.2e-08 32.5 0.0 0.027 14.1 0.0 3.5 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 OAJ03226.1 - 1.6e-05 24.4 0.1 0.00041 19.8 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 OAJ03226.1 - 1.7e-05 24.3 3.1 0.12 11.8 0.1 3.1 2 1 1 3 3 3 2 Protein phosphatase 2C Rad60-SLD PF11976.3 OAJ03227.1 - 4.7e-24 83.8 0.2 5.6e-24 83.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ03227.1 - 4.2e-10 38.8 0.0 5.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family tRNA-synt_1b PF00579.20 OAJ03228.1 - 5.8e-59 199.6 0.0 2e-58 197.8 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Methyltransf_2 PF00891.13 OAJ03229.1 - 1.3e-30 106.3 0.0 1.7e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_18 PF12847.2 OAJ03229.1 - 0.00069 20.1 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03229.1 - 0.094 12.4 0.1 3.8 7.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.13 OAJ03231.1 - 6.5e-28 97.5 0.0 4.8e-27 94.7 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 OAJ03231.1 - 0.0041 17.2 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 1 Transcriptional regulator HTH_27 PF13463.1 OAJ03231.1 - 0.014 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain RPA_C PF08784.6 OAJ03231.1 - 0.014 15.7 0.0 0.052 13.9 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal HTH_IclR PF09339.5 OAJ03231.1 - 0.016 14.7 0.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 0 IclR helix-turn-helix domain DSBA PF01323.15 OAJ03231.1 - 0.021 14.3 0.0 1.5 8.3 0.0 2.5 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Methyltransf_18 PF12847.2 OAJ03231.1 - 0.024 15.2 0.0 0.069 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HTH_24 PF13412.1 OAJ03231.1 - 0.18 11.2 0.0 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HA2 PF04408.18 OAJ03233.1 - 2.2e-15 56.5 0.0 5.4e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ03233.1 - 2.3e-11 43.4 0.1 4.4e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ03233.1 - 3.2e-07 30.1 0.0 6.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ03233.1 - 8.5e-06 25.3 0.2 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 OAJ03233.1 - 4.7e-05 23.8 10.5 4.8e-05 23.8 0.3 4.2 4 0 0 4 4 4 1 Double-stranded RNA binding motif DUF1764 PF08576.5 OAJ03234.1 - 6.2e-16 59.0 29.7 1.9e-10 41.3 20.6 2.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) Macoilin PF09726.4 OAJ03234.1 - 0.34 9.1 19.2 0.41 8.8 13.3 1.0 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 OAJ03234.1 - 0.54 8.0 24.7 0.62 7.8 17.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC27 PF09507.5 OAJ03234.1 - 1 8.5 29.9 1.3 8.1 20.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 OAJ03234.1 - 2.7 6.3 26.0 3.3 6.0 18.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 EOS1 PF12326.3 OAJ03235.1 - 1.2e-17 63.9 0.0 2.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 N-glycosylation protein Cytochrome_CBB3 PF13442.1 OAJ03236.1 - 1e-07 31.9 1.5 1.5e-06 28.2 1.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAJ03236.1 - 3.8e-07 30.8 0.4 4.6e-07 30.5 0.3 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 OAJ03236.1 - 0.0096 15.3 2.1 0.082 12.3 1.4 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain eRF1_2 PF03464.10 OAJ03237.1 - 7.2e-43 146.1 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 OAJ03237.1 - 8.2e-37 125.9 0.0 1.7e-36 124.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 OAJ03237.1 - 6.9e-26 90.3 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 EMP24_GP25L PF01105.19 OAJ03238.1 - 2.2e-38 131.8 0.3 2.2e-38 131.8 0.2 1.4 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD JmjC PF02373.17 OAJ03239.1 - 1.9e-38 131.1 0.1 3.5e-38 130.3 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ03239.1 - 6e-15 54.4 0.2 1.3e-14 53.4 0.2 1.6 1 0 0 1 1 1 1 jmjN domain SDA1 PF05285.7 OAJ03239.1 - 0.0033 16.7 2.1 0.0033 16.7 1.5 2.6 1 1 1 2 2 2 1 SDA1 Dimer_Tnp_hAT PF05699.9 OAJ03240.1 - 6.3e-11 41.7 0.0 1.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1764 PF08576.5 OAJ03240.1 - 0.037 14.7 0.3 0.037 14.7 0.2 5.2 5 1 1 6 6 6 0 Eukaryotic protein of unknown function (DUF1764) PPR_2 PF13041.1 OAJ03241.1 - 3.6e-36 122.8 0.0 1.1e-12 47.6 0.0 9.0 7 2 3 10 10 10 6 PPR repeat family PPR_3 PF13812.1 OAJ03241.1 - 2e-30 102.4 0.2 4.4e-06 26.5 0.0 9.8 11 0 0 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.15 OAJ03241.1 - 1.1e-24 84.6 6.6 3e-05 23.7 0.0 11.0 12 2 0 12 12 12 3 PPR repeat PPR_1 PF12854.2 OAJ03241.1 - 4.6e-17 61.1 8.5 3e-07 29.7 0.0 6.6 8 1 0 8 8 8 3 PPR repeat DUF605 PF04652.11 OAJ03241.1 - 9.5 5.4 20.9 17 4.6 14.5 1.3 1 0 0 1 1 1 0 Vta1 like PPR_2 PF13041.1 OAJ03242.1 - 6.3e-34 115.7 0.2 1.9e-07 30.9 0.0 9.5 8 2 2 10 10 10 7 PPR repeat family PPR PF01535.15 OAJ03242.1 - 3e-21 73.8 1.1 0.0036 17.1 0.1 10.7 12 2 0 12 12 12 4 PPR repeat PPR_3 PF13812.1 OAJ03242.1 - 1.5e-17 62.3 20.5 0.0066 16.6 0.0 13.2 15 0 0 15 15 15 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 OAJ03242.1 - 1.5e-10 40.3 8.3 0.0032 16.8 0.0 8.7 10 0 0 10 10 10 3 PPR repeat TPR_14 PF13428.1 OAJ03242.1 - 1.7e-05 25.0 14.1 1.9 9.3 0.1 8.3 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03242.1 - 0.00031 20.3 0.1 3.6 7.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03242.1 - 0.054 13.4 0.1 25 5.0 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1648 PF07853.6 OAJ03243.1 - 0.055 12.9 0.2 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Ad_cyc_g-alpha PF08509.6 OAJ03243.1 - 0.17 11.2 1.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain DUF155 PF02582.9 OAJ03244.1 - 5.7e-33 114.2 1.1 1.7e-16 60.5 0.0 2.7 3 1 0 3 3 3 2 Uncharacterised ACR, YagE family COG1723 eIF3_N PF09440.5 OAJ03245.1 - 5.2e-40 136.6 1.4 5.2e-40 136.6 1.0 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 OAJ03245.1 - 2.2e-09 37.5 0.1 4.4e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 OAJ03245.1 - 0.0077 15.9 2.1 2 8.3 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ03245.1 - 0.68 10.1 2.9 1.7 8.8 0.2 2.9 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 OAJ03245.1 - 0.86 9.6 4.3 3.4 7.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.15 OAJ03246.1 - 5e-30 104.7 0.1 8.2e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain RRM_1 PF00076.17 OAJ03247.1 - 5.4e-08 32.3 0.0 8.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03247.1 - 3.9e-07 29.9 0.0 5.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03247.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bin3 PF06859.7 OAJ03248.1 - 4.9e-14 52.2 0.0 9.5e-08 32.0 0.0 3.1 3 0 0 3 3 3 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 OAJ03248.1 - 2.5e-05 24.8 0.0 8.8e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03248.1 - 0.00056 19.5 0.0 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03248.1 - 0.022 14.8 0.0 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ03248.1 - 0.04 13.6 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ03248.1 - 0.043 14.2 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ03248.1 - 0.044 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03248.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ03248.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GMC_oxred_N PF00732.14 OAJ03249.1 - 1e-39 136.4 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ03249.1 - 2.5e-21 76.4 0.5 3e-19 69.7 0.6 3.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ03249.1 - 2.7e-08 33.0 0.3 6.4e-06 25.2 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ03249.1 - 2.6e-06 26.5 1.4 5.1e-05 22.3 0.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ03249.1 - 8.9e-05 22.4 0.3 0.00022 21.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 OAJ03249.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 OAJ03249.1 - 0.00031 20.6 0.2 0.00078 19.3 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ03249.1 - 0.01 14.3 0.5 0.02 13.3 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 OAJ03249.1 - 0.018 14.1 0.3 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 OAJ03249.1 - 0.028 13.8 0.4 0.051 13.0 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAJ03249.1 - 0.034 13.0 0.1 0.053 12.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 OAJ03249.1 - 0.045 12.8 1.2 0.066 12.2 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 OAJ03249.1 - 0.06 12.2 0.1 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.27 OAJ03250.1 - 3.6e-64 210.5 21.9 2.7e-11 42.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ03250.1 - 3.4e-05 22.1 5.9 0.058 11.5 0.2 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 OAJ03250.1 - 0.0017 18.1 0.0 0.0056 16.3 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 OAJ03250.1 - 0.062 11.5 0.0 3.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 OAJ03250.1 - 0.43 10.3 2.6 41 3.9 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Hexapep_2 PF14602.1 OAJ03251.1 - 3.5e-11 42.4 5.8 6.3e-11 41.6 3.4 1.9 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 OAJ03251.1 - 3.8e-11 41.9 7.9 1.9e-09 36.5 3.9 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ03251.1 - 6.3e-10 38.9 0.0 1.7e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Maltose acetyltransferase CAF-1_p150 PF11600.3 OAJ03252.1 - 0.29 10.4 4.8 0.33 10.2 3.3 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glycos_transf_1 PF00534.15 OAJ03253.1 - 1.9e-18 66.4 0.0 2.8e-13 49.6 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 OAJ03253.1 - 2.4e-05 24.1 2.4 0.00036 20.3 0.0 3.3 4 0 0 4 4 4 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 OAJ03253.1 - 0.00036 20.7 0.9 0.00036 20.7 0.6 3.7 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 OAJ03253.1 - 0.0037 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_11 PF13414.1 OAJ03254.1 - 7.2e-47 156.9 39.0 1e-13 50.6 4.3 7.4 2 2 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 OAJ03254.1 - 9e-29 97.8 24.6 1.5e-06 27.5 0.8 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03254.1 - 1.5e-27 93.2 30.5 1.3e-05 24.7 0.0 11.2 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ03254.1 - 6.3e-24 84.0 25.2 1.1e-08 35.4 0.0 6.6 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ03254.1 - 1.8e-19 68.2 17.7 3.5e-05 23.6 0.1 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ03254.1 - 4.7e-19 68.1 25.4 1.4e-05 24.9 0.0 7.5 3 2 7 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03254.1 - 1e-14 53.0 15.7 0.0014 18.2 0.3 8.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03254.1 - 4.4e-12 45.5 25.0 0.071 13.7 0.0 9.9 4 3 7 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ03254.1 - 1.5e-11 44.2 16.5 0.004 17.2 0.7 5.2 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAJ03254.1 - 1.6e-11 44.3 23.2 0.0026 18.0 0.6 6.3 4 1 3 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03254.1 - 1.2e-06 27.9 19.3 1 9.3 0.1 8.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ03254.1 - 5.1e-06 26.2 16.2 0.0086 15.9 0.2 6.2 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ03254.1 - 0.0057 17.0 0.1 0.0057 17.0 0.0 8.2 11 0 0 11 11 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ03254.1 - 0.012 15.7 12.2 3.2 7.9 0.0 5.6 3 2 3 6 6 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 OAJ03254.1 - 0.034 13.9 0.3 0.6 9.9 0.1 3.0 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF3856 PF12968.2 OAJ03254.1 - 0.069 12.9 12.1 0.36 10.6 0.1 5.4 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) DDE_Tnp_1 PF01609.16 OAJ03254.1 - 0.1 12.0 0.1 0.38 10.2 0.1 1.9 1 1 1 2 2 2 0 Transposase DDE domain TPR_4 PF07721.9 OAJ03254.1 - 0.74 10.4 7.3 15 6.4 0.0 5.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 OAJ03254.1 - 1 9.3 6.1 14 5.6 0.0 4.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 OAJ03254.1 - 1.8 8.6 19.5 4.3 7.3 0.0 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF3557 PF12078.3 OAJ03258.1 - 0.063 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Kinesin-related PF06548.6 OAJ03259.1 - 0.0069 14.9 0.1 0.0097 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin-related GLTSCR1 PF15249.1 OAJ03259.1 - 0.047 13.8 0.2 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region HALZ PF02183.13 OAJ03259.1 - 0.052 13.2 1.2 0.1 12.3 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 OAJ03259.1 - 0.22 11.2 5.3 0.52 10.0 3.7 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain M PF02370.11 OAJ03259.1 - 0.3 11.5 4.2 0.76 10.3 2.9 1.7 1 0 0 1 1 1 0 M protein repeat Mito_fiss_reg PF05308.6 OAJ03259.1 - 0.41 9.9 11.2 0.014 14.7 1.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Nop14 PF04147.7 OAJ03260.1 - 2.9 5.6 6.4 5.1 4.8 4.4 1.3 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.17 OAJ03261.1 - 6.8e-25 86.4 0.0 6.4e-12 44.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03261.1 - 5.1e-15 55.2 0.0 5.9e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03262.1 - 6.8e-07 29.1 0.0 1.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 OAJ03262.1 - 7.9e-05 22.2 8.3 0.00022 20.8 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ03262.1 - 0.5 10.1 10.1 1 9.1 7.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 OAJ03262.1 - 2.1 8.0 10.5 4.8 6.9 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HLH PF00010.21 OAJ03263.1 - 0.00011 21.7 0.0 0.015 14.9 0.2 2.4 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain WD40 PF00400.27 OAJ03264.1 - 0.01 15.7 19.5 0.48 10.3 0.1 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Peptidase_C48 PF02902.14 OAJ03265.1 - 4.1e-08 33.1 0.7 2.1e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF3187 PF11383.3 OAJ03265.1 - 0.091 11.8 0.5 0.16 11.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) RhoGEF PF00621.15 OAJ03266.1 - 6.8e-18 65.1 0.2 2e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 RhoGEF domain Ribosomal_60s PF00428.14 OAJ03266.1 - 0.0016 18.7 3.1 0.0016 18.7 2.2 4.4 5 0 0 5 5 5 1 60s Acidic ribosomal protein Nop14 PF04147.7 OAJ03266.1 - 0.56 8.0 2.1 10 3.9 2.5 2.0 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L7Ae PF01248.21 OAJ03267.1 - 1.8e-21 75.4 0.2 2.6e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ03267.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 Arch_ATPase PF01637.13 OAJ03267.1 - 0.1 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase Myosin_head PF00063.16 OAJ03268.1 - 2.8e-248 825.4 1.7 3.9e-248 825.0 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 OAJ03268.1 - 4.5e-17 61.0 72.7 4.5e-17 61.0 50.4 3.6 1 1 3 4 4 4 3 Myosin tail Myosin_N PF02736.14 OAJ03268.1 - 0.0014 18.2 0.8 0.004 16.7 0.6 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 OAJ03268.1 - 0.0086 15.8 0.9 0.037 13.7 0.6 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ03268.1 - 0.21 11.7 0.0 0.21 11.7 0.0 4.3 3 1 2 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 OAJ03268.1 - 0.22 10.6 48.5 0.0063 15.7 3.7 5.4 1 1 4 5 5 5 0 Reovirus sigma C capsid protein IQ PF00612.22 OAJ03268.1 - 0.28 10.9 4.2 0.57 9.9 0.9 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif SIP1 PF04938.7 OAJ03269.1 - 4.7e-16 58.8 0.3 8.3e-15 54.7 0.2 2.3 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3680 PF12441.3 OAJ03269.1 - 0.089 12.6 0.2 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3680) PIG-U PF06728.8 OAJ03270.1 - 1.2e-95 320.5 6.7 1.4e-95 320.3 4.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Chromo PF00385.19 OAJ03271.1 - 5.7e-09 35.5 3.9 1.4e-08 34.2 2.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ03271.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Chromo shadow domain DUF2057 PF09829.4 OAJ03271.1 - 0.32 10.6 0.1 0.32 10.6 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) MSP1_C PF07462.6 OAJ03271.1 - 9.5 4.4 7.4 0.9 7.8 0.6 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Lin-8 PF03353.10 OAJ03272.1 - 9.2 5.4 6.4 1.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DEAD PF00270.24 OAJ03273.1 - 1.5e-35 122.1 0.1 3.1e-35 121.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03273.1 - 7.6e-20 70.5 0.0 1.8e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ03273.1 - 7e-14 51.1 0.0 1.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ03273.1 - 2.4e-06 27.4 0.1 1e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4137 PF13593.1 OAJ03273.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.1 OAJ03273.1 - 0.015 15.4 0.0 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.4 OAJ03273.1 - 9.6 5.6 32.1 0.066 12.6 16.2 1.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ctr PF04145.10 OAJ03274.1 - 1.7e-17 63.8 0.3 6.6e-16 58.6 0.2 2.2 1 1 0 1 1 1 1 Ctr copper transporter family CBFD_NFYB_HMF PF00808.18 OAJ03275.1 - 1.3e-06 28.3 0.2 3.2e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 OAJ03275.1 - 0.00016 20.8 18.9 0.0002 20.5 13.1 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 OAJ03275.1 - 0.00036 20.5 13.7 0.00042 20.3 9.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 OAJ03275.1 - 0.0047 16.7 1.4 0.0047 16.7 0.9 2.0 2 0 0 2 2 2 1 Peptidase family S49 N-terminal eIF-3c_N PF05470.7 OAJ03275.1 - 0.65 8.0 11.4 0.96 7.4 7.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pilt PF15453.1 OAJ03275.1 - 1.9 8.0 13.0 2.8 7.5 9.0 1.4 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions MIP-T3 PF10243.4 OAJ03275.1 - 2.5 6.4 27.1 35 2.6 0.0 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 OAJ03275.1 - 8.9 5.4 28.1 13 4.8 19.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.17 OAJ03276.1 - 2.4e-05 23.8 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 OAJ03276.1 - 4.2e-05 23.2 0.3 9.3e-05 22.1 0.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 OAJ03276.1 - 4.5e-05 23.2 0.0 9.3e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03276.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.1 OAJ03276.1 - 0.71 8.7 3.6 1.3 7.8 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GRAB PF10375.4 OAJ03277.1 - 3.2e-05 23.3 0.7 3.2e-05 23.3 0.5 2.5 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Citrate_synt PF00285.16 OAJ03277.1 - 0.017 13.8 7.5 0.043 12.5 5.2 1.7 1 0 0 1 1 1 0 Citrate synthase AAA_13 PF13166.1 OAJ03277.1 - 2.2 6.6 21.9 0.39 9.1 10.9 2.1 2 0 0 2 2 2 0 AAA domain NPV_P10 PF05531.7 OAJ03277.1 - 3 8.1 9.7 53 4.1 3.1 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.11 OAJ03277.1 - 5.1 7.1 45.7 0.13 12.2 5.7 4.2 1 1 2 3 3 3 0 Flagellar FliJ protein Prefoldin PF02996.12 OAJ03277.1 - 6.8 6.3 19.2 5.4 6.6 0.6 4.5 3 1 0 4 4 4 0 Prefoldin subunit DNA_primase_S PF01896.14 OAJ03278.1 - 1.1e-52 177.6 0.0 1.8e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HTH_36 PF13730.1 OAJ03278.1 - 0.023 14.8 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain INCENP_ARK-bind PF03941.10 OAJ03279.1 - 1.9e-05 24.4 0.4 8.8e-05 22.2 0.2 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF948 PF06103.6 OAJ03280.1 - 1.2 9.0 5.4 2.1 8.2 0.1 3.8 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Aconitase PF00330.15 OAJ03281.1 - 4.2e-182 605.7 0.0 5e-182 605.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ03281.1 - 2.3e-44 150.6 0.0 4.7e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain CsbD PF05532.7 OAJ03281.1 - 0.076 12.7 2.0 0.16 11.7 1.4 1.5 1 0 0 1 1 1 0 CsbD-like CTF_NFI PF00859.13 OAJ03281.1 - 0.093 12.4 0.1 0.22 11.2 0.1 1.5 2 0 0 2 2 2 0 CTF/NF-I family transcription modulation region Cyt-b5 PF00173.23 OAJ03282.1 - 1e-26 92.5 0.0 1.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Y_phosphatase2 PF03162.8 OAJ03283.1 - 2.2e-56 189.7 0.0 3.3e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 OAJ03283.1 - 1.1e-06 28.9 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ03283.1 - 0.00037 19.9 0.1 0.001 18.4 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ03283.1 - 0.0049 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Nop14 PF04147.7 OAJ03283.1 - 2.1 6.1 5.6 3.6 5.3 3.9 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_transf_22 PF03901.12 OAJ03285.1 - 3.2e-38 131.8 1.5 5.1e-38 131.1 1.1 1.3 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DEAD PF00270.24 OAJ03286.1 - 1.1e-29 103.0 0.0 1.8e-28 99.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03286.1 - 2.9e-18 65.4 0.0 1.4e-16 60.0 0.2 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Lambda_CIII PF02061.11 OAJ03286.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Lambda Phage CIII CMS1 PF14617.1 OAJ03286.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_hydro_35 PF01301.14 OAJ03288.1 - 1.8e-70 237.8 0.0 3.1e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 OAJ03288.1 - 2.4e-34 117.9 0.2 3.9e-19 68.9 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 OAJ03288.1 - 3.3e-29 101.5 0.6 7.1e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 OAJ03288.1 - 3.6e-06 26.2 0.0 1.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 OAJ03288.1 - 0.0037 16.4 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 OAJ03289.1 - 2.2e-26 91.2 16.6 1.1e-11 44.2 0.1 7.0 5 1 2 7 7 7 5 TPR repeat TPR_1 PF00515.23 OAJ03289.1 - 3.8e-17 61.0 10.1 2.3e-06 26.9 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03289.1 - 1.1e-16 59.2 23.8 0.0005 19.7 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ03289.1 - 3.2e-10 39.3 0.4 0.45 10.8 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03289.1 - 1.9e-09 36.5 0.1 0.11 12.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ03289.1 - 7.2e-09 36.0 1.8 4.3e-07 30.4 0.1 9.1 9 1 0 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ03289.1 - 2.3e-08 34.2 18.3 1.9e-05 24.9 0.6 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ03289.1 - 6.3e-07 29.2 19.8 1.5e-05 24.8 0.1 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03289.1 - 1e-06 28.0 11.1 0.0085 15.8 0.1 7.6 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03289.1 - 3.8e-06 27.0 50.9 0.029 14.9 0.1 10.8 9 1 4 13 13 9 5 Tetratricopeptide repeat Apc3 PF12895.2 OAJ03289.1 - 0.00012 22.1 10.2 1.1 9.4 0.0 5.6 5 1 3 8 8 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAJ03289.1 - 0.0022 17.8 1.2 0.0022 17.8 0.8 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Nop14 PF04147.7 OAJ03289.1 - 0.033 12.1 23.0 0.05 11.5 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ03289.1 - 0.043 11.8 15.3 0.076 11.0 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 OAJ03289.1 - 0.15 11.2 24.4 0.27 10.4 16.9 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ03289.1 - 0.24 9.8 30.2 0.4 9.1 20.9 1.2 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 OAJ03289.1 - 4.6 6.7 17.1 10 5.6 11.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.7 OAJ03289.1 - 6.9 4.9 19.6 15 3.8 13.6 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 OAJ03289.1 - 9.8 5.4 16.3 21 4.4 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1325 PF07039.6 OAJ03296.1 - 1.1e-28 99.4 0.0 1.5e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain PGM_PMM_I PF02878.11 OAJ03297.1 - 1.2e-39 134.9 0.2 1.9e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ03297.1 - 1.9e-22 79.5 0.1 6.8e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 OAJ03297.1 - 1.3e-11 44.5 0.0 2.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 OAJ03297.1 - 1.9e-07 30.9 0.0 6.7e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pyridox_oxase_2 PF12766.2 OAJ03298.1 - 7.9e-21 74.2 0.0 1.5e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH_1 PF13423.1 OAJ03300.1 - 7.1e-36 124.1 0.0 1.2e-35 123.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 OAJ03300.1 - 7.7e-20 71.8 0.0 1.3e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 OAJ03300.1 - 0.002 17.3 0.0 0.45 9.5 0.0 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 OAJ03300.1 - 0.0027 17.5 0.3 0.023 14.5 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat 2-Hacid_dh_C PF02826.14 OAJ03302.1 - 1.1e-52 177.7 0.0 1.9e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ03302.1 - 2.9e-34 117.3 0.0 3.9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 OAJ03302.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HhH-GPD PF00730.20 OAJ03304.1 - 8e-17 61.4 0.0 1.5e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ03304.1 - 1.4e-08 33.9 0.0 6.5e-08 31.8 0.0 2.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 OAJ03304.1 - 0.039 14.1 0.0 0.31 11.2 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 OAJ03304.1 - 1.2 9.4 5.8 2.8 8.2 4.0 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III BRCA-2_OB1 PF09103.5 OAJ03305.1 - 1e-28 99.4 0.0 1.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 OAJ03305.1 - 3.4e-08 33.3 0.3 5.5e-08 32.6 0.2 1.3 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.13 OAJ03305.1 - 4.5e-05 22.6 0.1 8.7e-05 21.7 0.1 1.4 1 0 0 1 1 1 1 BRCA2 repeat Aldedh PF00171.17 OAJ03306.1 - 4e-105 351.8 0.1 4.8e-105 351.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-CCHC PF00098.18 OAJ03307.1 - 0.05 13.5 4.9 0.091 12.7 3.4 1.4 1 0 0 1 1 1 0 Zinc knuckle TAFII55_N PF04658.8 OAJ03308.1 - 9.4e-49 165.0 0.0 9.4e-49 165.0 0.0 2.2 2 0 0 2 2 2 1 TAFII55 protein conserved region NIF PF03031.13 OAJ03309.1 - 6.4e-22 77.9 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 OAJ03309.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Mre11_DNA_bind PF04152.9 OAJ03310.1 - 7.6e-43 146.3 2.9 7.6e-43 146.3 2.0 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 OAJ03310.1 - 6.6e-24 84.4 0.3 1e-23 83.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 OAJ03310.1 - 6e-07 29.4 0.0 1.9e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3333 PF11812.3 OAJ03310.1 - 0.087 12.8 0.0 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DHFR_1 PF00186.14 OAJ03311.1 - 1.1e-27 96.6 0.0 4.2e-26 91.4 0.0 2.5 1 1 0 1 1 1 1 Dihydrofolate reductase RVT_1 PF00078.22 OAJ03312.1 - 3.9e-18 65.5 0.0 7.2e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03312.1 - 6.1e-14 52.1 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ03312.1 - 9.6e-05 22.8 0.1 0.00089 19.7 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ03312.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Phospholip_B PF04916.8 OAJ03312.1 - 0.035 12.2 0.0 0.057 11.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B RVP PF00077.15 OAJ03312.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Ras PF00071.17 OAJ03314.1 - 1.7e-45 154.3 0.0 2.1e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ03314.1 - 1.2e-11 45.0 0.0 1.8e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ03314.1 - 2.2e-05 23.8 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ03314.1 - 0.0006 19.3 0.0 0.0029 17.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ03314.1 - 0.021 13.9 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 OAJ03314.1 - 0.07 13.0 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ03314.1 - 0.092 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glutaredoxin PF00462.19 OAJ03314.1 - 0.1 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin Sulfate_tra_GLY PF13792.1 OAJ03315.1 - 0.088 12.4 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Peroxin-13_N PF04088.8 OAJ03316.1 - 2.9e-46 157.3 0.0 4.3e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 OAJ03316.1 - 1.7e-12 46.6 0.0 2.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ03316.1 - 3e-12 45.7 0.0 5.7e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 OAJ03316.1 - 1.8e-11 43.4 0.0 2.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex2_Pex12 PF04757.9 OAJ03316.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF1242 PF06842.7 OAJ03317.1 - 2.9e-18 65.0 1.5 3.9e-18 64.6 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.1 OAJ03317.1 - 0.22 11.5 0.5 0.35 10.9 0.4 1.3 1 0 0 1 1 1 0 Jag N-terminus LSR PF05624.9 OAJ03317.1 - 0.48 10.1 2.9 0.2 11.3 0.4 1.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) UAA PF08449.6 OAJ03318.1 - 2e-72 243.6 4.6 1.2e-54 185.3 0.0 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 OAJ03318.1 - 0.00023 20.3 0.7 0.00034 19.7 0.1 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter Tetraspannin PF00335.15 OAJ03318.1 - 0.72 9.0 5.4 0.34 10.1 0.4 2.4 2 0 0 2 2 2 0 Tetraspanin family NUDIX_2 PF13869.1 OAJ03319.1 - 2.8e-80 268.0 0.0 3.2e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Mito_carr PF00153.22 OAJ03320.1 - 1.9e-68 226.2 2.2 3.7e-23 81.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 OAJ03321.1 - 1.2e-16 60.1 0.0 2.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03321.1 - 7.3e-12 45.0 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03321.1 - 3.5e-08 33.1 0.0 6.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ03321.1 - 0.031 14.0 0.0 7.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Nop14 PF04147.7 OAJ03321.1 - 1.3 6.8 19.2 0.0056 14.6 6.4 1.8 2 0 0 2 2 2 0 Nop14-like family RRN3 PF05327.6 OAJ03321.1 - 1.6 6.7 3.4 2 6.3 2.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RVT_2 PF07727.9 OAJ03322.1 - 7.1e-88 293.7 0.0 1.1e-87 293.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03322.1 - 2.4e-29 101.8 0.1 6.4e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ03322.1 - 4.8e-06 26.1 0.2 1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ03322.1 - 2.1e-05 23.9 0.0 8.1e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain ATP-synt_C PF00137.16 OAJ03323.1 - 2.1e-28 98.0 31.7 1.4e-16 60.1 7.9 3.0 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 OAJ03323.1 - 3.2 7.3 9.6 0.14 11.7 0.9 2.7 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4078 PF13300.1 OAJ03324.1 - 9.8e-17 60.8 0.9 9.8e-17 60.8 0.6 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) Exo_endo_phos PF03372.18 OAJ03325.1 - 3.2e-10 40.3 0.3 1.4e-09 38.2 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acyl-CoA_dh_1 PF00441.19 OAJ03326.1 - 1.1e-43 148.9 1.7 1.8e-43 148.2 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ03326.1 - 3.5e-34 117.7 0.0 6.4e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ03326.1 - 7.8e-19 66.9 0.1 2e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ03326.1 - 9.7e-17 61.4 0.3 1.4e-16 60.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 OAJ03326.1 - 0.1 12.8 0.0 0.77 10.0 0.0 2.1 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal CPSase_L_D2 PF02786.12 OAJ03327.1 - 4.6e-73 244.9 0.0 1.2e-72 243.5 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 OAJ03327.1 - 4.3e-36 123.1 0.0 8.1e-36 122.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAJ03327.1 - 2e-22 79.4 0.0 5.2e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 OAJ03327.1 - 1.3e-14 54.3 0.1 6.4e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 OAJ03327.1 - 4.7e-14 51.7 3.3 1.2e-13 50.4 2.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 OAJ03327.1 - 1.8e-08 34.0 0.0 1.3e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 OAJ03327.1 - 4.5e-08 32.2 0.0 3.9e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 OAJ03327.1 - 3.1e-07 29.9 1.0 3e-06 26.7 0.5 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ03327.1 - 9.9e-06 25.0 0.0 1.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ03327.1 - 0.00026 21.2 4.0 0.064 13.6 0.0 3.2 3 0 0 3 3 3 2 HlyD family secretion protein HlyD PF00529.15 OAJ03327.1 - 0.0058 15.9 1.7 0.035 13.4 0.2 2.3 2 0 0 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 OAJ03327.1 - 0.047 13.3 0.7 0.091 12.4 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.9 OAJ03327.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 OAJ03327.1 - 0.13 11.7 0.0 1 8.7 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain FliD_N PF02465.13 OAJ03327.1 - 0.26 11.6 2.1 0.62 10.4 1.4 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Brix PF04427.13 OAJ03328.1 - 7e-37 126.9 0.0 1.1e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 OAJ03328.1 - 0.001 17.1 12.7 0.0011 17.0 1.2 2.4 2 0 0 2 2 2 2 Nop14-like family DUF2890 PF11081.3 OAJ03328.1 - 0.067 13.2 9.3 0.25 11.3 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Daxx PF03344.10 OAJ03328.1 - 1.3 7.4 20.7 0.13 10.7 1.9 2.1 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 OAJ03328.1 - 1.3 6.9 17.2 0.15 10.0 4.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Spt5_N PF11942.3 OAJ03328.1 - 1.4 9.5 29.8 0.29 11.7 1.0 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Sporozoite_P67 PF05642.6 OAJ03328.1 - 1.6 6.4 7.9 2.5 5.8 0.6 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 OAJ03328.1 - 2.9 5.4 8.0 0.23 9.1 1.0 1.9 2 0 0 2 2 2 0 Ycf1 ECIST_Cterm PF14784.1 OAJ03328.1 - 4.5 7.2 6.3 1 9.3 0.6 2.5 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein DDHD PF02862.12 OAJ03328.1 - 8.8 6.0 8.3 1.4 8.6 1.7 2.2 2 0 0 2 2 2 0 DDHD domain Inhibitor_I9 PF05922.11 OAJ03329.1 - 2.6e-08 34.2 0.1 1e-07 32.3 0.1 1.7 1 1 0 1 1 1 1 Peptidase inhibitor I9 COX7C PF02935.11 OAJ03330.1 - 3e-10 39.7 0.6 3.6e-10 39.4 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Snf7 PF03357.16 OAJ03331.1 - 8.2e-33 113.1 12.1 1.2e-32 112.6 8.4 1.2 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.1 OAJ03331.1 - 0.1 12.2 1.6 0.28 10.8 1.1 1.8 1 0 0 1 1 1 0 TIP39 peptide C1q PF00386.16 OAJ03331.1 - 0.15 12.0 0.4 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 C1q domain AAA_23 PF13476.1 OAJ03332.1 - 0.002 18.4 1.7 0.45 10.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain Trep_Strep PF09605.5 OAJ03332.1 - 0.006 16.2 0.1 4.3 6.9 0.0 2.4 2 0 0 2 2 2 2 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4199 PF13858.1 OAJ03332.1 - 0.037 13.9 12.6 2.5 7.9 0.9 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) Spc7 PF08317.6 OAJ03333.1 - 9.7e-11 40.8 1.7 1.8e-10 40.0 1.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein BSP_II PF05432.6 OAJ03333.1 - 0.00021 20.7 12.2 0.011 15.0 0.6 2.3 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) DUF3584 PF12128.3 OAJ03333.1 - 0.0049 14.2 4.8 0.0074 13.6 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Spc7_C2 PF15577.1 OAJ03333.1 - 0.019 14.5 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 Spc7_C2 FlgN PF05130.7 OAJ03333.1 - 0.38 10.9 7.4 0.92 9.7 5.1 1.7 1 1 0 1 1 1 0 FlgN protein Prothymosin PF03247.9 OAJ03333.1 - 3.9 7.6 31.2 2.1 8.5 9.8 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family Keratin_B2_2 PF13885.1 OAJ03333.1 - 4.1 7.2 11.4 0.58 9.9 4.0 2.6 2 1 0 2 2 2 0 Keratin, high sulfur B2 protein TLP-20 PF06088.6 OAJ03333.1 - 6.9 6.3 8.8 5.1 6.7 0.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) ERCC4 PF02732.10 OAJ03334.1 - 5.4e-25 87.8 0.1 1e-24 86.9 0.0 1.5 2 0 0 2 2 2 1 ERCC4 domain SAM_PNT PF02198.11 OAJ03334.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PQ-loop PF04193.9 OAJ03341.1 - 7.6e-16 57.4 0.6 1.9e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 PQ loop repeat DUF1301 PF06979.7 OAJ03341.1 - 0.051 13.7 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) Retinal PF15449.1 OAJ03341.1 - 0.83 7.2 11.8 0.99 6.9 8.2 1.0 1 0 0 1 1 1 0 Retinal protein Herpes_capsid PF06112.6 OAJ03341.1 - 3.5 7.6 7.9 6.1 6.8 5.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ENTH PF01417.15 OAJ03342.1 - 1.7e-43 147.4 0.1 2.3e-43 147.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAJ03342.1 - 0.0022 16.7 0.1 0.0032 16.2 0.1 1.1 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 OAJ03342.1 - 0.049 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 VHS domain TPR_12 PF13424.1 OAJ03343.1 - 1.4e-17 63.3 36.4 9.4e-07 28.6 1.7 6.6 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ03343.1 - 2.7e-09 36.6 27.9 0.16 11.9 0.2 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc5 PF12862.2 OAJ03343.1 - 1.2e-05 25.0 8.0 0.0087 15.8 0.1 5.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 OAJ03343.1 - 4.4e-05 23.3 8.2 0.029 14.5 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ03343.1 - 7.2e-05 22.2 5.7 1.4 8.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03343.1 - 0.00024 20.7 20.9 0.073 13.0 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03343.1 - 0.00029 20.3 6.2 0.42 10.4 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03343.1 - 0.0018 17.9 0.9 0.0018 17.9 0.6 6.4 4 2 4 8 8 8 3 TPR repeat TPR_6 PF13174.1 OAJ03343.1 - 0.009 16.4 11.7 55 4.5 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03343.1 - 0.039 14.5 25.8 16 6.5 0.2 8.9 8 2 2 10 10 10 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 OAJ03343.1 - 0.73 9.1 0.0 0.73 9.1 0.0 3.2 4 0 0 4 4 4 0 SHNi-TPR TPR_16 PF13432.1 OAJ03343.1 - 3.9 8.2 26.8 2.8 8.7 0.3 6.4 4 2 3 8 8 7 0 Tetratricopeptide repeat AAA PF00004.24 OAJ03344.1 - 6.7e-44 149.2 0.0 1.2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 OAJ03344.1 - 2.2e-08 34.2 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ03344.1 - 1.7e-06 27.7 0.0 7.3e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 OAJ03344.1 - 1.8e-06 28.0 0.0 0.00033 20.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ03344.1 - 2.3e-06 27.7 0.1 1.4e-05 25.2 0.0 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAJ03344.1 - 6.4e-05 22.6 0.0 0.00018 21.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 OAJ03344.1 - 7.6e-05 23.5 0.0 0.00019 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ03344.1 - 8e-05 21.7 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 OAJ03344.1 - 0.00043 19.7 0.0 0.00089 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 OAJ03344.1 - 0.001 17.8 0.0 0.002 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 OAJ03344.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ03344.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ03344.1 - 0.0026 16.8 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 OAJ03344.1 - 0.0034 16.6 0.0 0.069 12.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 OAJ03344.1 - 0.0038 17.1 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 OAJ03344.1 - 0.004 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ03344.1 - 0.006 16.1 0.0 0.047 13.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 OAJ03344.1 - 0.0077 15.4 0.1 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 OAJ03344.1 - 0.0091 16.3 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF2072 PF09845.4 OAJ03344.1 - 0.014 15.3 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) KaiC PF06745.8 OAJ03344.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 OAJ03344.1 - 0.02 14.3 0.1 0.082 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 OAJ03344.1 - 0.021 14.2 0.1 0.098 12.1 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 OAJ03344.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 OAJ03344.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 OAJ03344.1 - 0.047 13.3 0.0 0.59 9.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 OAJ03344.1 - 0.057 12.2 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 OAJ03344.1 - 0.057 13.4 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 OAJ03344.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Aa_trans PF01490.13 OAJ03345.1 - 3.3e-56 190.5 7.9 1.9e-55 187.9 5.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein BUD22 PF09073.5 OAJ03345.1 - 0.071 12.1 20.8 0.11 11.5 14.4 1.2 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 OAJ03345.1 - 1.2 7.5 13.4 1.9 6.8 9.3 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 OAJ03345.1 - 2.5 7.3 14.5 4 6.6 10.1 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 OAJ03345.1 - 5.1 4.8 18.9 7.9 4.2 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family SPRR2 PF14820.1 OAJ03346.1 - 0.0046 16.8 4.8 0.0079 16.0 3.3 1.3 1 0 0 1 1 1 1 Small proline-rich 2 TATR PF03430.8 OAJ03346.1 - 4.9 5.6 6.4 0.15 10.6 0.3 1.4 2 0 0 2 2 2 0 Trans-activating transcriptional regulator Amidase PF01425.16 OAJ03347.1 - 8.5e-80 268.7 0.1 1.8e-64 218.2 0.5 2.1 2 0 0 2 2 2 2 Amidase ResIII PF04851.10 OAJ03348.1 - 2.8e-17 63.1 0.0 6e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ03348.1 - 3.6e-13 49.3 0.0 6.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03348.1 - 1.1e-12 47.6 0.0 2.7e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 OAJ03348.1 - 0.0012 18.4 0.0 0.006 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ03348.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ03348.1 - 0.0019 17.8 1.6 0.41 10.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain T2SE PF00437.15 OAJ03348.1 - 0.0032 16.3 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SNF2_N PF00176.18 OAJ03348.1 - 0.0052 15.6 0.0 0.0082 14.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain cobW PF02492.14 OAJ03348.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 OAJ03348.1 - 0.016 15.2 0.0 0.055 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 OAJ03348.1 - 0.034 13.1 0.0 0.067 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 OAJ03348.1 - 0.16 12.2 2.6 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 OAJ03348.1 - 0.25 10.2 0.0 3.8 6.3 0.0 2.1 1 1 0 1 1 1 0 PIF1-like helicase DUF3395 PF11875.3 OAJ03348.1 - 0.28 10.8 4.6 0.75 9.4 3.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) ISG65-75 PF11727.3 OAJ03348.1 - 1.9 7.4 7.9 4.4 6.2 3.7 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein Pex24p PF06398.6 OAJ03349.1 - 2.6e-30 105.4 2.4 3.2e-29 101.8 0.4 2.3 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Cation_ATPase_N PF00690.21 OAJ03350.1 - 1.5e-06 27.5 0.0 2.2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 OAJ03350.1 - 0.007 15.4 0.0 0.0091 15.0 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Asp-B-Hydro_N PF05279.6 OAJ03352.1 - 0.22 11.3 3.9 0.32 10.8 2.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Plasmid_stabil PF05016.9 OAJ03352.1 - 0.3 11.5 0.2 0.3 11.5 0.1 1.9 2 1 0 2 2 2 0 Plasmid stabilisation system protein Cnd3 PF12719.2 OAJ03356.1 - 0.096 11.6 0.1 0.16 10.8 0.1 1.3 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF4192 PF13830.1 OAJ03356.1 - 0.13 11.9 14.5 0.18 11.3 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Urease_gamma PF00547.13 OAJ03356.1 - 0.23 11.5 3.5 0.4 10.7 2.5 1.3 1 0 0 1 1 1 0 Urease, gamma subunit Spore_coat_CotO PF14153.1 OAJ03356.1 - 1.4 8.3 8.0 1.9 7.9 5.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TPR_12 PF13424.1 OAJ03357.1 - 4.3e-15 55.4 25.5 3.5e-06 26.8 0.3 6.8 4 2 4 8 8 8 6 Tetratricopeptide repeat Apc5 PF12862.2 OAJ03357.1 - 0.00048 19.8 10.6 0.33 10.8 0.1 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 OAJ03357.1 - 0.00053 19.5 13.0 0.14 11.8 0.1 6.2 5 1 3 8 8 8 2 TPR repeat TPR_10 PF13374.1 OAJ03357.1 - 0.0013 18.5 24.7 0.31 11.0 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ03357.1 - 0.0099 16.2 1.9 17 6.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ03357.1 - 0.071 12.9 8.5 0.2 11.4 0.4 3.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.12 OAJ03357.1 - 0.65 10.0 21.4 29 4.9 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat GatB_Yqey PF02637.13 OAJ03358.1 - 0.04 13.6 0.2 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 GatB domain eIF2A PF08662.6 OAJ03360.1 - 4.1e-09 36.4 0.0 5.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAJ03360.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat DPPIV_N PF00930.16 OAJ03360.1 - 0.064 11.8 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region LOH1CR12 PF10158.4 OAJ03365.1 - 0.009 15.8 2.1 4.3 7.1 0.8 2.6 2 0 0 2 2 2 2 Tumour suppressor protein Peptidase_C15 PF01470.12 OAJ03365.1 - 0.18 11.6 1.1 0.35 10.6 0.8 1.4 1 0 0 1 1 1 0 Pyroglutamyl peptidase KTI12 PF08433.5 OAJ03365.1 - 0.36 9.9 6.5 0.94 8.6 4.5 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4611 PF15387.1 OAJ03365.1 - 8.9 6.5 12.2 0.55 10.4 0.8 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4611) PQ-loop PF04193.9 OAJ03366.1 - 5.8e-35 118.6 7.2 6.5e-19 67.2 0.8 2.9 2 0 0 2 2 2 2 PQ loop repeat DUF1301 PF06979.7 OAJ03366.1 - 0.047 13.8 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) DDE_Tnp_4 PF13359.1 OAJ03367.1 - 3.1e-37 127.6 0.1 9.3e-37 126.0 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.9 OAJ03367.1 - 7.2e-06 25.5 0.0 3.1e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DDE_Tnp_1 PF01609.16 OAJ03367.1 - 1.5e-05 24.6 0.8 0.00011 21.7 0.5 2.1 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 OAJ03367.1 - 0.075 12.5 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease LysM PF01476.15 OAJ03367.1 - 0.084 12.7 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 LysM domain DUF2414 PF10309.4 OAJ03374.1 - 3e-07 30.0 0.0 5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) BUD22 PF09073.5 OAJ03376.1 - 0.95 8.4 13.3 1.7 7.6 9.2 1.3 1 1 0 1 1 1 0 BUD22 Apt1 PF10351.4 OAJ03376.1 - 1.9 7.2 5.5 2.9 6.6 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DASH_Spc19 PF08287.6 OAJ03377.1 - 3.6e-22 78.6 6.2 8.5e-22 77.4 4.3 1.6 1 1 0 1 1 1 1 Spc19 Filament PF00038.16 OAJ03377.1 - 0.0031 17.0 4.1 0.019 14.4 2.8 1.9 1 1 0 1 1 1 1 Intermediate filament protein BLOC1_2 PF10046.4 OAJ03377.1 - 0.34 11.0 5.0 1.1 9.4 0.2 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sipho_Gp157 PF05565.6 OAJ03377.1 - 0.82 9.2 6.1 7.7 6.0 0.3 2.3 1 1 1 2 2 2 0 Siphovirus Gp157 DUF972 PF06156.8 OAJ03377.1 - 1.7 9.0 6.9 7.5 6.9 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Enkurin PF13864.1 OAJ03377.1 - 2.5 8.3 7.8 1.4 9.1 0.1 3.2 3 1 0 3 3 3 0 Calmodulin-binding Atg14 PF10186.4 OAJ03377.1 - 2.8 6.8 14.2 4 6.3 5.0 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GCN5L1 PF06320.8 OAJ03377.1 - 4.2 7.2 10.4 0.49 10.2 0.3 2.4 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) K-box PF01486.12 OAJ03377.1 - 4.6 7.0 7.9 1.6 8.5 0.4 3.1 2 1 0 3 3 3 0 K-box region AhpC-TSA PF00578.16 OAJ03378.1 - 7.2e-06 25.6 0.0 3.7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 OAJ03378.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Na_trans_assoc PF06512.8 OAJ03380.1 - 0.037 13.9 5.9 0.1 12.5 0.4 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated TFIIF_alpha PF05793.7 OAJ03380.1 - 2.9 6.1 13.1 0.36 9.1 0.5 2.5 3 0 0 3 3 3 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BRO1 PF03097.13 OAJ03381.1 - 7.3e-19 67.7 0.0 6e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 BRO1-like domain DUF913 PF06025.7 OAJ03382.1 - 3e-93 312.5 0.0 3e-93 312.5 0.0 4.5 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 OAJ03382.1 - 8.7e-73 245.4 0.4 3.5e-72 243.4 0.2 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 OAJ03382.1 - 6.2e-25 87.2 1.2 6.2e-25 87.2 0.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 OAJ03382.1 - 1.1e-09 37.8 0.1 3.1e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain OrfB_Zn_ribbon PF07282.6 OAJ03384.1 - 9.2e-16 57.2 0.2 1.5e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.3 OAJ03384.1 - 7.5e-07 28.3 0.4 1.6e-06 27.3 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.14 OAJ03384.1 - 0.00039 19.8 0.0 0.00096 18.6 0.0 1.6 1 1 0 1 1 1 1 Probable transposase DUF346 PF03984.8 OAJ03384.1 - 0.13 11.7 1.0 0.54 9.7 0.1 2.3 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Fasciclin PF02469.17 OAJ03385.1 - 2.2e-15 56.7 0.1 5.7e-08 32.8 0.0 4.5 4 0 0 4 4 4 4 Fasciclin domain Far-17a_AIG1 PF04750.9 OAJ03386.1 - 1e-38 132.5 1.6 1.3e-38 132.2 1.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Inositol_P PF00459.20 OAJ03387.1 - 5.7e-53 179.9 0.6 4.7e-52 176.9 0.4 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2766 PF10964.3 OAJ03389.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2766) Antimicrobial10 PF08105.6 OAJ03390.1 - 0.08 12.5 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Metchnikowin family FSH1 PF03959.8 OAJ03391.1 - 5.6e-54 182.8 0.0 6.5e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 OAJ03391.1 - 8.8e-07 29.0 0.4 3.3e-05 23.8 0.0 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ03391.1 - 0.00024 20.8 0.0 0.00039 20.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAJ03391.1 - 0.0048 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 OAJ03391.1 - 0.0056 16.1 0.1 0.082 12.3 0.1 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase IGPD PF00475.13 OAJ03392.1 - 3.5e-60 202.0 0.4 5e-60 201.5 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DUF2917 PF11142.3 OAJ03392.1 - 0.1 11.8 0.1 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2917) Oxysterol_BP PF01237.13 OAJ03394.1 - 1.1e-81 274.0 0.0 1.4e-81 273.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Tyrosinase PF00264.15 OAJ03396.1 - 5.5e-36 124.7 0.8 8.1e-36 124.2 0.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PIN_4 PF13638.1 OAJ03398.1 - 2.9e-19 69.4 0.1 2.9e-19 69.4 0.1 2.4 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 OAJ03398.1 - 6.6e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Nop53 PF07767.6 OAJ03399.1 - 1.6e-46 159.0 31.7 6.7e-24 84.5 7.1 2.6 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) CPSase_sm_chain PF00988.17 OAJ03400.1 - 3.7e-43 146.1 0.0 5.9e-43 145.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 OAJ03400.1 - 1.9e-36 125.3 0.0 1.7e-35 122.2 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 OAJ03400.1 - 1.2e-05 24.9 0.1 9.4e-05 21.9 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 OAJ03400.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family CASP_C PF08172.7 OAJ03401.1 - 2.4e-64 216.7 0.0 2.4e-64 216.7 0.0 3.8 3 1 1 4 4 4 1 CASP C terminal HALZ PF02183.13 OAJ03401.1 - 0.91 9.2 17.4 1.6 8.4 0.8 5.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper DivIVA PF05103.8 OAJ03401.1 - 1.6 8.8 50.9 1.2 9.1 8.8 6.4 5 1 1 6 6 6 0 DivIVA protein Rootletin PF15035.1 OAJ03401.1 - 8.7 6.2 51.7 0.41 10.6 0.4 5.2 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion Pantoate_transf PF02548.10 OAJ03402.1 - 4.9e-88 294.6 0.5 2.1e-83 279.4 0.2 2.3 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 OAJ03402.1 - 6.7e-05 22.2 1.3 0.00013 21.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Bax1-I PF01027.15 OAJ03404.1 - 1.7e-44 151.8 22.2 2.4e-44 151.4 15.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_I5 PF04713.7 OAJ03404.1 - 0.75 9.5 9.5 0.32 10.7 0.2 3.0 2 1 0 2 2 2 0 Poxvirus protein I5 DUF3464 PF11947.3 OAJ03404.1 - 1.7 8.0 5.7 2.8 7.3 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) STE2 PF02116.10 OAJ03411.1 - 0.33 9.9 7.5 0.074 12.0 0.6 2.2 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR MerC PF03203.9 OAJ03411.1 - 0.58 10.5 6.5 3.6 8.0 0.2 3.3 4 0 0 4 4 4 0 MerC mercury resistance protein DUF4336 PF14234.1 OAJ03412.1 - 0.00028 20.1 0.0 0.03 13.4 0.0 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Ribosomal_60s PF00428.14 OAJ03413.1 - 0.029 14.7 2.6 0.067 13.5 1.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF912 PF06024.7 OAJ03413.1 - 0.071 13.1 0.2 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF962 PF06127.6 OAJ03415.1 - 0.82 9.6 3.9 3.7 7.5 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF962) SMK-1 PF04802.10 OAJ03417.1 - 1.6e-71 239.8 2.6 3.2e-71 238.8 1.8 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Sybindin PF04099.7 OAJ03418.1 - 1e-07 31.7 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family Heme_oxygenase PF01126.15 OAJ03419.1 - 6.5e-09 35.6 0.0 5.1e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 Heme oxygenase Cwf_Cwc_15 PF04889.7 OAJ03420.1 - 1.1 8.8 6.4 1.4 8.6 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HIPIP PF01355.12 OAJ03420.1 - 1.1 9.3 4.0 5.1 7.2 0.4 2.2 1 1 1 2 2 2 0 High potential iron-sulfur protein PUF PF00806.14 OAJ03422.1 - 3.9e-59 192.9 16.3 4.1e-08 32.2 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 OAJ03422.1 - 0.0013 19.0 0.1 0.15 12.3 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function DUF260 SRP14 PF02290.10 OAJ03423.1 - 1.1e-14 54.0 0.2 1e-13 50.9 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle 14kD protein PhdYeFM_antitox PF02604.14 OAJ03423.1 - 0.36 10.4 0.0 0.36 10.4 0.0 2.5 3 1 0 3 3 3 0 Antitoxin Phd_YefM, type II toxin-antitoxin system HECT_2 PF09814.4 OAJ03425.1 - 1.3e-31 109.5 0.0 1.5e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding MULE PF10551.4 OAJ03427.1 - 2.1e-16 59.8 0.0 4.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.10 OAJ03427.1 - 8.1e-06 25.3 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase Transposase_mut PF00872.13 OAJ03427.1 - 1e-05 24.2 0.0 1.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 OAJ03427.1 - 0.00016 21.0 0.4 0.00016 21.0 0.3 1.9 2 0 0 2 2 2 1 SWIM zinc finger zf-CCHC_2 PF13696.1 OAJ03427.1 - 0.16 11.4 0.2 0.16 11.4 0.1 2.1 3 0 0 3 3 3 0 Zinc knuckle PHD PF00628.24 OAJ03427.1 - 1.8 8.3 5.8 10 5.9 0.2 3.0 3 0 0 3 3 3 0 PHD-finger SWIM PF04434.12 OAJ03428.1 - 0.004 16.6 1.0 0.0079 15.6 0.7 1.5 1 0 0 1 1 1 1 SWIM zinc finger Asp_protease_2 PF13650.1 OAJ03429.1 - 0.00013 22.4 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ03429.1 - 0.0064 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 OAJ03429.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 OAJ03429.1 - 0.028 14.2 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SWIM PF04434.12 OAJ03430.1 - 0.011 15.2 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger Bromo_TP PF07524.8 OAJ03432.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Spb1_C PF07780.7 OAJ03433.1 - 4.1e-67 225.8 39.7 4.1e-67 225.8 27.5 3.8 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 OAJ03433.1 - 4.9e-53 179.7 0.0 1.4e-52 178.3 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 OAJ03433.1 - 2.2e-40 137.7 10.0 2.2e-40 137.7 7.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) Cys_Met_Meta_PP PF01053.15 OAJ03434.1 - 1.6e-132 441.4 0.0 3.2e-132 440.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 OAJ03434.1 - 3.8e-06 25.4 0.0 5.4e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 OAJ03434.1 - 0.00044 19.0 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ03434.1 - 0.0058 15.6 0.0 0.0084 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Nop14 PF04147.7 OAJ03440.1 - 0.009 13.9 11.2 0.013 13.5 7.8 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 OAJ03440.1 - 0.042 13.4 12.4 0.076 12.6 8.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Daxx PF03344.10 OAJ03440.1 - 0.13 10.7 19.5 0.018 13.5 10.7 1.4 1 1 0 1 1 1 0 Daxx Family TIMELESS_C PF05029.8 OAJ03440.1 - 0.16 10.8 9.7 0.22 10.4 6.7 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region SDA1 PF05285.7 OAJ03440.1 - 0.31 10.2 12.4 0.4 9.9 8.6 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 OAJ03440.1 - 0.42 10.2 6.7 0.56 9.7 4.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 OAJ03440.1 - 0.46 8.4 4.3 0.53 8.2 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.1 OAJ03440.1 - 0.47 10.3 3.9 0.84 9.4 2.7 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 CENP-B_dimeris PF09026.5 OAJ03440.1 - 1.3 9.3 14.9 2.2 8.5 10.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ03440.1 - 1.6 9.0 18.1 6.3 7.1 12.5 2.1 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ03440.1 - 1.9 8.0 16.4 3 7.3 11.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin TLP-20 PF06088.6 OAJ03440.1 - 2.3 7.8 5.7 4.4 6.9 4.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) NOA36 PF06524.7 OAJ03440.1 - 3.9 6.6 9.6 5.7 6.1 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.1 OAJ03440.1 - 8 6.6 14.2 14 5.7 9.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DDE_Tnp_4 PF13359.1 OAJ03441.1 - 2.4e-26 92.2 0.0 3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ03441.1 - 0.00085 18.9 0.1 0.0061 16.1 0.1 2.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 OAJ03441.1 - 0.00086 19.4 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.9 OAJ03441.1 - 0.0033 16.8 0.0 0.0082 15.5 0.0 1.6 2 0 0 2 2 2 1 Plant transposon protein BCA_ABC_TP_C PF12399.3 OAJ03441.1 - 0.17 11.5 0.3 0.85 9.3 0.0 2.2 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter PQ-loop PF04193.9 OAJ03447.1 - 8.6e-36 121.3 6.5 7.4e-18 63.8 1.0 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 OAJ03447.1 - 0.045 13.6 0.4 0.045 13.6 0.2 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Asn_synthase PF00733.16 OAJ03448.1 - 2.3e-68 230.4 0.0 5.2e-68 229.2 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 OAJ03448.1 - 3.2e-38 130.2 0.0 5.6e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAJ03448.1 - 3.3e-30 104.7 0.0 1.6e-29 102.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ03448.1 - 1.5e-06 27.1 0.2 0.012 14.3 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 OAJ03448.1 - 1.5e-05 24.3 0.0 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 OAJ03448.1 - 0.047 12.5 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.8 OAJ03448.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC F-box PF00646.28 OAJ03449.1 - 1.9e-07 30.5 0.1 3.3e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ03449.1 - 4.8e-07 29.4 0.5 9.1e-07 28.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 OAJ03449.1 - 0.0054 16.4 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ribosomal_S8e PF01201.17 OAJ03453.1 - 5.3e-38 130.1 8.4 4.5e-37 127.1 5.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 OAJ03453.1 - 0.0041 17.0 0.1 0.0041 17.0 0.0 1.8 2 0 0 2 2 2 1 Mer2 GSH_synth_ATP PF03917.12 OAJ03454.1 - 2.4e-78 263.3 0.0 2.4e-37 128.4 0.0 3.7 1 1 1 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 OAJ03454.1 - 1.9e-29 101.8 0.0 4.2e-29 100.7 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase PC_rep PF01851.17 OAJ03459.1 - 1.4e-43 144.7 20.2 3.7e-09 36.3 0.0 10.5 11 0 0 11 11 11 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 OAJ03459.1 - 1.2e-19 70.3 4.9 3.1e-11 43.3 0.0 4.7 2 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 OAJ03459.1 - 4.9e-07 29.2 2.2 1.3 9.2 0.0 5.0 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 OAJ03459.1 - 1.7e-06 28.3 9.6 0.025 15.0 0.1 5.3 5 1 2 7 7 7 3 HEAT-like repeat HEAT_PBS PF03130.11 OAJ03459.1 - 0.007 16.7 1.7 1.1e+02 3.7 0.0 6.0 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat TPR_19 PF14559.1 OAJ03459.1 - 0.99 9.7 7.0 3.2 8.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SAICAR_synt PF01259.13 OAJ03460.1 - 9.9e-80 267.2 0.0 1.5e-61 207.6 0.0 2.2 2 0 0 2 2 2 2 SAICAR synthetase Pro-kuma_activ PF09286.6 OAJ03460.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain SCA7 PF08313.7 OAJ03461.1 - 6.9e-27 92.8 0.7 2.2e-26 91.2 0.5 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Pro-kuma_activ PF09286.6 OAJ03462.1 - 4e-18 65.8 0.0 7.9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 OAJ03462.1 - 3.6e-11 42.7 3.2 3.6e-11 42.7 2.3 1.7 2 0 0 2 2 2 1 Subtilase family MAM33 PF02330.11 OAJ03462.1 - 0.15 11.7 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial glycoprotein CRM1_C PF08767.6 OAJ03463.1 - 1.8e-121 404.9 1.0 1.8e-121 404.9 0.7 2.5 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 OAJ03463.1 - 1.1e-40 138.9 4.9 4.3e-40 137.0 1.1 3.7 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 OAJ03463.1 - 5.7e-13 48.5 0.5 2.5e-12 46.5 0.3 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Response_reg PF00072.19 OAJ03465.1 - 2.1e-18 66.3 0.0 4.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 OAJ03465.1 - 1.3e-16 60.2 0.2 2.4e-16 59.4 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ03465.1 - 1.4e-07 31.4 0.4 1.4e-07 31.4 0.3 2.7 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Sec7 PF01369.15 OAJ03466.1 - 3.3e-36 124.7 0.0 5.2e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 OAJ03466.1 - 7.7e-07 29.2 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 OAJ03466.1 - 0.0045 17.1 0.3 0.0045 17.1 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PMM PF03332.8 OAJ03467.1 - 3e-102 340.8 0.3 3.5e-102 340.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 OAJ03467.1 - 4.8e-05 23.0 0.0 0.00062 19.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.7 OAJ03467.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF600 DUF1640 PF07798.6 OAJ03468.1 - 1.5e-08 34.8 7.0 1.7e-08 34.6 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OmpH PF03938.9 OAJ03468.1 - 0.021 14.7 5.4 0.024 14.5 3.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SF-assemblin PF06705.6 OAJ03468.1 - 0.036 13.1 7.2 0.078 12.1 5.0 1.7 1 1 0 1 1 1 0 SF-assemblin/beta giardin ORF6C PF10552.4 OAJ03468.1 - 0.073 12.8 1.9 0.22 11.2 0.8 2.0 1 1 0 2 2 2 0 ORF6C domain DUF4635 PF15466.1 OAJ03468.1 - 0.16 11.2 1.8 0.26 10.5 1.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) DUF4549 PF15082.1 OAJ03468.1 - 0.18 11.4 2.6 5.2 6.7 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Lzipper-MIP1 PF14389.1 OAJ03468.1 - 0.23 11.6 5.5 0.71 10.0 1.1 2.6 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Apolipoprotein PF01442.13 OAJ03468.1 - 0.25 10.8 7.6 0.39 10.2 5.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Kinetocho_Slk19 PF12709.2 OAJ03468.1 - 0.25 11.4 3.0 0.36 10.9 1.3 1.8 1 1 0 1 1 1 0 Central kinetochore-associated Fzo_mitofusin PF04799.8 OAJ03468.1 - 0.29 10.5 4.4 0.33 10.3 2.7 1.4 1 1 0 1 1 1 0 fzo-like conserved region GBP_C PF02841.9 OAJ03468.1 - 0.47 9.5 6.7 0.54 9.3 4.6 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CCDC-167 PF15188.1 OAJ03468.1 - 0.49 10.3 6.0 0.48 10.3 3.2 1.7 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.7 OAJ03468.1 - 0.52 10.1 6.6 1.4 8.7 2.1 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 OAJ03468.1 - 0.61 10.5 6.7 1.8 8.9 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TMF_DNA_bd PF12329.3 OAJ03468.1 - 0.7 9.7 8.3 0.86 9.4 4.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.6 OAJ03468.1 - 0.75 10.2 4.4 2.2 8.7 3.1 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Allexi_40kDa PF05549.6 OAJ03468.1 - 0.8 8.9 4.6 1.7 7.8 3.2 1.5 1 1 0 1 1 1 0 Allexivirus 40kDa protein F-box PF00646.28 OAJ03469.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 OAJ03469.1 - 0.035 13.8 0.2 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like WAC_Acf1_DNA_bd PF10537.4 OAJ03470.1 - 1.1e-33 115.4 0.0 3e-33 114.0 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 OAJ03470.1 - 2e-12 46.6 0.0 5.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 OAJ03470.1 - 1.1e-05 25.1 0.3 2.9e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 OAJ03470.1 - 0.018 14.9 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 tRNA-synt_1d PF00750.14 OAJ03471.1 - 9.1e-83 277.9 1.4 1.3e-82 277.4 1.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 OAJ03471.1 - 3e-20 72.3 0.0 8.4e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain DUF3975 PF13126.1 OAJ03472.1 - 2.2 8.4 7.0 0.36 11.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) DUF373 PF04123.8 OAJ03472.1 - 2.6 6.9 8.5 4.8 6.0 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Ank_2 PF12796.2 OAJ03474.1 - 9.5e-45 150.8 4.5 8.9e-21 74.0 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ03474.1 - 5.5e-36 120.5 6.2 1.1e-08 34.4 0.0 7.6 7 0 0 7 7 7 7 Ankyrin repeat SPX PF03105.14 OAJ03474.1 - 4.3e-34 118.5 2.2 3e-19 69.8 0.0 2.8 3 1 0 3 3 3 2 SPX domain Ank_4 PF13637.1 OAJ03474.1 - 5e-30 103.3 4.9 4.1e-10 39.8 0.0 5.8 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ03474.1 - 1.4e-27 95.0 11.7 6.6e-06 26.1 0.1 7.5 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ03474.1 - 2.4e-23 79.8 1.8 0.0019 18.2 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat GDPD PF03009.12 OAJ03474.1 - 6.3e-14 52.0 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-C2H2 PF00096.21 OAJ03475.1 - 2.7e-06 27.3 4.7 0.0075 16.5 0.1 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 OAJ03475.1 - 4.6e-05 23.4 5.6 0.01 15.9 0.4 2.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 OAJ03475.1 - 7.9e-05 22.7 4.4 0.0033 17.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 OAJ03475.1 - 0.00011 22.2 1.9 0.077 13.1 0.2 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 OAJ03475.1 - 0.087 12.9 0.9 1.2 9.2 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) HypA PF01155.14 OAJ03475.1 - 0.1 12.3 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C2H2_6 PF13912.1 OAJ03475.1 - 0.14 12.1 2.1 0.25 11.2 0.1 2.3 1 1 1 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ03475.1 - 0.29 11.4 5.6 0.73 10.2 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double domain PyrI_C PF02748.10 OAJ03475.1 - 0.71 9.3 3.0 0.94 8.9 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 OAJ03475.1 - 2.3 8.5 5.6 18 5.8 1.2 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Ribosomal_60s PF00428.14 OAJ03476.1 - 4.7e-26 91.0 5.5 5.6e-26 90.7 3.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.20 OAJ03477.1 - 3.4e-69 232.8 0.0 4.1e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03477.1 - 2.1e-30 105.6 0.0 2.7e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ03477.1 - 0.00029 19.8 0.0 0.1 11.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 OAJ03477.1 - 0.041 12.7 0.0 0.068 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 OAJ03477.1 - 0.093 12.4 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Bac_luciferase PF00296.15 OAJ03478.1 - 0.081 12.0 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase 14-3-3 PF00244.15 OAJ03483.1 - 1e-118 394.5 5.3 1.2e-118 394.3 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 OAJ03483.1 - 0.0098 15.4 3.6 1 8.8 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF837) HisKA PF00512.20 OAJ03483.1 - 0.12 12.4 2.2 2.5 8.1 0.1 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain Nucleoplasmin PF03066.10 OAJ03484.1 - 0.0081 15.6 1.3 0.4 10.1 0.8 2.2 2 0 0 2 2 2 1 Nucleoplasmin Sugar_tr PF00083.19 OAJ03484.1 - 0.83 8.1 7.1 0.34 9.4 0.0 3.4 3 1 1 4 4 4 0 Sugar (and other) transporter DUF4611 PF15387.1 OAJ03484.1 - 4.7 7.4 8.8 17 5.6 3.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sigma70_ner PF04546.8 OAJ03484.1 - 5 6.6 8.3 7.5 6.0 0.9 3.0 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF4094 PF13334.1 OAJ03485.1 - 1.6 9.1 0.0 1.6 9.1 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) CytochromB561_N PF09786.4 OAJ03485.1 - 6.5 5.0 20.8 0.064 11.7 7.2 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal UPF0515 PF15135.1 OAJ03486.1 - 0.1 11.6 0.1 0.1 11.6 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 zf-C2H2_4 PF13894.1 OAJ03486.1 - 8.3 6.9 25.1 0.11 12.8 1.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Tom5 PF10642.4 OAJ03487.1 - 0.28 10.8 3.7 0.16 11.6 0.7 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase HORMA PF02301.13 OAJ03488.1 - 1.3e-40 139.0 0.0 1.5e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain NIF PF03031.13 OAJ03489.1 - 3.8e-37 127.4 0.0 5.5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase tRNA-synt_2b PF00587.20 OAJ03490.1 - 2.1e-43 147.8 0.0 4e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ03490.1 - 2.5e-14 52.9 2.0 6.5e-12 45.2 1.4 2.4 1 1 0 1 1 1 1 Anticodon binding domain Preseq_ALAS PF09029.5 OAJ03490.1 - 0.16 11.9 0.6 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Reprolysin_5 PF13688.1 OAJ03490.1 - 3.1 7.6 6.8 4.8 7.0 3.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 AAA_22 PF13401.1 OAJ03491.1 - 1.3e-13 51.2 0.0 2.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 OAJ03491.1 - 3.6e-10 40.1 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ03491.1 - 2.8e-06 27.4 0.2 7.8e-05 22.7 0.2 2.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 OAJ03491.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 OAJ03491.1 - 0.00023 20.0 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 OAJ03491.1 - 0.0066 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ03491.1 - 0.068 12.8 0.1 0.23 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 OAJ03491.1 - 0.079 12.6 0.1 0.89 9.2 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase UbiA PF01040.13 OAJ03492.1 - 1.4e-23 83.4 22.2 2.3e-23 82.7 15.4 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Glucosamine_iso PF01182.15 OAJ03493.1 - 3.2e-66 222.8 0.0 3.8e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PTR PF12789.2 OAJ03496.1 - 0.046 13.5 0.1 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage tail repeat like Dimer_Tnp_hAT PF05699.9 OAJ03498.1 - 2e-10 40.1 1.2 5e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region SAGA-Tad1 PF12767.2 OAJ03501.1 - 1.4e-47 162.4 0.0 2.3e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF1675 PF07897.6 OAJ03501.1 - 1.8 8.3 6.9 0.45 10.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1675) Adaptin_N PF01602.15 OAJ03502.1 - 1.4e-122 409.6 6.6 1.7e-122 409.4 4.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 OAJ03502.1 - 2.3e-41 140.3 0.0 6.9e-41 138.7 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 OAJ03502.1 - 4.1e-18 65.7 0.0 3.1e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.17 OAJ03502.1 - 0.49 10.6 4.3 8.2 6.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L5_C PF00673.16 OAJ03503.1 - 2.8e-05 23.7 0.0 9.4e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Alg14 PF08660.6 OAJ03504.1 - 5e-43 147.0 0.0 7.1e-42 143.2 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Tmemb_9 PF05434.6 OAJ03504.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 TMEM9 SHS2_Rpb7-N PF03876.12 OAJ03505.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf-CCHC PF00098.18 OAJ03506.1 - 1.3e-07 31.2 1.3 2.1e-07 30.5 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ03506.1 - 0.023 14.1 1.5 0.045 13.2 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Tup_N PF08581.5 OAJ03506.1 - 0.047 13.8 4.0 0.12 12.6 0.2 2.6 3 0 0 3 3 3 0 Tup N-terminal Retrotrans_gag PF03732.12 OAJ03506.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_4 PF14392.1 OAJ03506.1 - 0.13 11.9 0.7 0.26 10.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.17 OAJ03507.1 - 6.9e-80 262.6 1.7 5e-19 67.7 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03507.1 - 1.2e-52 175.7 0.2 2.6e-15 56.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03507.1 - 2.5e-41 139.2 2.2 8.8e-13 47.9 0.0 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAJ03507.1 - 8.2e-27 92.6 0.6 8.2e-27 92.6 0.4 3.0 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 OAJ03507.1 - 0.00095 18.8 0.6 4.4 7.1 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 OAJ03507.1 - 0.011 15.9 0.1 4.2 7.6 0.0 3.3 3 0 0 3 3 3 0 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 OAJ03507.1 - 0.054 13.2 1.5 20 5.0 0.1 3.5 4 0 0 4 4 4 0 Limkain b1 GrpE PF01025.14 OAJ03508.1 - 5.1e-43 146.4 0.1 6.9e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 GrpE DUF4552 PF15089.1 OAJ03509.1 - 0.43 9.4 0.5 0.71 8.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) PGAP1 PF07819.8 OAJ03510.1 - 2.7e-05 23.8 0.0 4.8e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 OAJ03510.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ03510.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 OAJ03510.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Kdo PF06293.9 OAJ03511.1 - 0.00011 21.3 0.0 0.0065 15.5 0.0 2.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ03511.1 - 0.00012 21.9 0.1 1.1 8.9 0.1 3.2 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 OAJ03511.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 OAJ03511.1 - 0.031 13.4 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.17 OAJ03511.1 - 0.044 13.1 0.0 6.6 6.0 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Sel1 PF08238.7 OAJ03512.1 - 6.8e-15 55.1 21.3 1.2e-05 25.7 0.5 4.4 4 0 0 4 4 4 3 Sel1 repeat Med4 PF10018.4 OAJ03512.1 - 0.025 13.9 0.0 0.057 12.8 0.0 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 TPR_11 PF13414.1 OAJ03512.1 - 0.076 12.6 4.6 1.4 8.5 0.0 3.0 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 OAJ03512.1 - 4.1 7.5 5.8 8.3 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.14 OAJ03513.1 - 7e-29 99.4 6.6 9.9e-29 98.9 4.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DNA_topoisoIV PF00521.15 OAJ03514.1 - 2.8e-128 428.4 0.5 7.2e-128 427.0 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 OAJ03514.1 - 7.2e-35 119.7 1.2 1.8e-34 118.4 0.8 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 OAJ03514.1 - 2.1e-14 53.2 0.0 1.4e-13 50.6 0.0 2.5 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 OAJ03514.1 - 2.9e-08 33.4 0.0 6.5e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Atg14 PF10186.4 OAJ03515.1 - 9.8e-18 64.1 4.4 1.5e-17 63.5 3.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 OAJ03515.1 - 0.018 14.7 5.1 0.049 13.3 3.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ALO PF04030.9 OAJ03515.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DUF202 PF02656.10 OAJ03516.1 - 1.7e-05 24.9 1.8 0.00024 21.2 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Allene_ox_cyc PF06351.6 OAJ03516.1 - 0.044 13.2 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Allene oxide cyclase Ctr PF04145.10 OAJ03516.1 - 0.096 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Mito_carr PF00153.22 OAJ03521.1 - 3e-71 235.2 2.0 3.6e-26 90.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein X PF00739.14 OAJ03521.1 - 0.045 13.6 0.7 1.1 9.1 1.4 2.4 2 0 0 2 2 2 0 Trans-activation protein X Nop14 PF04147.7 OAJ03521.1 - 9.2 4.0 5.9 12 3.6 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Dus PF01207.12 OAJ03522.1 - 2.8e-44 151.1 0.0 1.4e-24 86.4 0.0 3.1 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) Pkinase PF00069.20 OAJ03523.1 - 2.2e-71 240.0 0.1 4.2e-65 219.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03523.1 - 3.8e-36 124.4 0.1 2.2e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 OAJ03523.1 - 3.1e-18 64.9 0.4 5.6e-18 64.1 0.3 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 OAJ03523.1 - 3e-05 23.1 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 OAJ03523.1 - 0.0022 17.7 0.0 0.017 14.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ03523.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WaaY PF06176.6 OAJ03523.1 - 0.16 11.1 0.3 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Ribosomal_L14 PF00238.14 OAJ03524.1 - 6.6e-42 142.1 1.0 7.9e-42 141.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Redoxin PF08534.5 OAJ03525.1 - 9.1e-07 28.5 0.0 4.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 OAJ03525.1 - 2e-05 24.2 0.0 3.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.1 OAJ03525.1 - 4e-05 23.5 0.0 6.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme RVT_2 PF07727.9 OAJ03526.1 - 1.3e-79 266.6 0.0 2.5e-79 265.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03526.1 - 5.6e-18 65.1 0.0 1.4e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAJ03526.1 - 2.9e-16 59.0 0.1 7.6e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ03526.1 - 2.6e-14 53.0 0.1 4.5e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ03526.1 - 4.1e-08 32.7 0.0 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ03526.1 - 0.00025 20.4 0.0 0.00071 19.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_2 PF13696.1 OAJ03526.1 - 0.0098 15.3 0.8 0.023 14.2 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ03526.1 - 0.017 14.9 7.0 0.04 13.8 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle RVP PF00077.15 OAJ03526.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease UBN2_3 PF14244.1 OAJ03526.1 - 0.061 12.8 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AA_permease PF00324.16 OAJ03528.1 - 1.4e-113 379.7 30.6 1.7e-113 379.4 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ03528.1 - 7.8e-34 116.9 33.6 9.8e-34 116.6 23.3 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 OAJ03528.1 - 0.019 15.0 0.4 0.019 15.0 0.3 3.5 4 0 0 4 4 4 0 PrgI family protein PAP2_3 PF14378.1 OAJ03528.1 - 1.2 8.6 7.4 0.087 12.3 0.3 2.5 3 0 0 3 3 3 0 PAP2 superfamily Nop14 PF04147.7 OAJ03529.1 - 8.7 4.1 24.3 13 3.4 16.9 1.4 1 0 0 1 1 1 0 Nop14-like family HTH_Tnp_4 PF13613.1 OAJ03530.1 - 0.062 12.8 0.1 0.18 11.3 0.1 1.8 1 1 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease FUSC PF04632.7 OAJ03530.1 - 1 7.7 6.6 1.2 7.4 4.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acyl_transf_1 PF00698.16 OAJ03531.1 - 2.2e-11 43.6 3.4 4.5e-06 26.2 0.0 3.5 3 1 0 3 3 3 3 Acyl transferase domain RPA_interact_C PF14768.1 OAJ03533.1 - 0.014 15.7 0.0 0.041 14.2 0.0 1.8 1 1 0 1 1 1 0 Replication protein A interacting C-terminal Mito_carr PF00153.22 OAJ03534.1 - 2.1e-67 222.8 1.1 2.9e-22 78.1 0.1 4.0 4 1 0 4 4 4 3 Mitochondrial carrier protein SoxE PF06525.6 OAJ03534.1 - 2.2 7.5 7.8 4.8 6.4 5.4 1.5 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF572 PF04502.8 OAJ03536.1 - 1.6e-83 280.6 5.7 2.8e-83 279.8 3.9 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 OAJ03536.1 - 0.055 13.8 0.4 0.055 13.8 0.3 1.8 2 0 0 2 2 2 0 HrpA pilus formation protein MRC1 PF09444.5 OAJ03536.1 - 0.056 13.7 7.2 0.12 12.7 5.0 1.5 1 0 0 1 1 1 0 MRC1-like domain Benyvirus_14KDa PF07255.6 OAJ03536.1 - 0.12 12.1 0.2 0.3 10.9 0.1 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein Lar_restr_allev PF14354.1 OAJ03536.1 - 0.17 12.2 0.9 6 7.2 1.1 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar Mt_ATP-synt_B PF05405.9 OAJ03537.1 - 0.031 13.7 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GDC-P PF02347.11 OAJ03538.1 - 4.9e-77 259.4 0.1 5.6e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Transposase_21 PF02992.9 OAJ03539.1 - 1.3e-14 53.8 0.0 3.9e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF3287 PF11690.3 OAJ03539.1 - 0.054 13.5 1.1 8.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF3306 PF11748.3 OAJ03540.1 - 0.076 13.6 2.0 0.35 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MULE PF10551.4 OAJ03541.1 - 1.2e-16 60.6 0.2 2.6e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ03541.1 - 1.6e-07 30.2 0.1 2.5e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Vps55 PF04133.9 OAJ03542.1 - 2.7e-43 146.5 4.3 3e-43 146.3 3.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Sec16_C PF12931.2 OAJ03543.1 - 3.9e-75 253.2 0.0 5.4e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 OAJ03543.1 - 3.8e-19 68.7 0.0 8.1e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region EamA PF00892.15 OAJ03544.1 - 7.1e-21 74.5 31.2 8.3e-15 54.9 3.9 3.9 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 OAJ03544.1 - 1.1e-07 32.0 4.5 1.1e-07 32.0 3.1 4.1 4 1 0 4 4 4 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 OAJ03544.1 - 0.0043 16.1 0.2 0.011 14.9 0.1 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 OAJ03544.1 - 0.045 13.3 14.8 0.085 12.4 1.7 3.2 3 1 0 3 3 3 0 Triose-phosphate Transporter family DUF3021 PF11457.3 OAJ03544.1 - 0.14 12.0 2.5 0.15 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) zf-RING_4 PF14570.1 OAJ03545.1 - 5.6e-21 73.8 11.5 9.1e-21 73.1 8.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 OAJ03545.1 - 1.1e-05 24.9 8.2 1.8e-05 24.2 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ03545.1 - 0.015 15.2 12.1 0.026 14.5 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 OAJ03545.1 - 0.019 14.8 0.0 0.11 12.3 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 OAJ03545.1 - 0.032 13.9 3.8 0.078 12.7 2.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_1 PF00076.17 OAJ03545.1 - 0.05 13.2 0.1 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 OAJ03545.1 - 1.1 9.0 7.9 0.92 9.2 4.3 1.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RPAP1_N PF08621.5 OAJ03546.1 - 2.3e-08 33.4 0.6 4.6e-08 32.5 0.4 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.5 OAJ03546.1 - 0.0049 16.6 1.6 0.0094 15.7 0.1 2.3 1 1 1 2 2 2 1 RPAP1-like, C-terminal His_Phos_1 PF00300.17 OAJ03547.1 - 1.2e-14 54.6 0.0 1.8e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MULE PF10551.4 OAJ03548.1 - 1.2e-14 54.1 0.0 3.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ03548.1 - 1.8e-07 30.0 1.5 5.5e-07 28.4 0.3 1.9 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.10 OAJ03548.1 - 0.0097 16.4 0.1 0.03 14.8 0.1 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain zf-CCHC PF00098.18 OAJ03548.1 - 0.035 14.0 3.7 0.078 12.9 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4206 PF13901.1 OAJ03548.1 - 0.39 10.2 7.7 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Hexapep PF00132.19 OAJ03549.1 - 2.7e-13 48.7 3.0 8.4e-11 40.8 1.3 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ03549.1 - 7.1e-12 44.6 4.7 4.8e-11 42.0 2.1 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 OAJ03549.1 - 8.6e-11 41.6 0.0 2.1e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Fasciclin PF02469.17 OAJ03550.1 - 7.8e-42 142.3 0.0 3.1e-10 40.1 0.0 7.0 6 2 0 6 6 6 5 Fasciclin domain Aminotran_1_2 PF00155.16 OAJ03551.1 - 8.2e-40 136.8 0.0 1.7e-39 135.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 OAJ03551.1 - 0.00033 19.0 0.0 0.00068 18.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3210 PF11489.3 OAJ03551.1 - 0.25 9.9 5.4 0.34 9.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) Hexapep PF00132.19 OAJ03553.1 - 1.3e-12 46.5 6.4 2.5e-10 39.3 2.5 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 OAJ03553.1 - 8.5e-12 44.9 0.0 2.2e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.1 OAJ03553.1 - 1.8e-11 43.3 6.3 4.1e-11 42.2 2.3 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase peroxidase PF00141.18 OAJ03555.1 - 1e-49 169.1 0.0 1.8e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Fungal_trans PF04082.13 OAJ03556.1 - 5.4e-08 32.0 0.0 9.4e-08 31.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ03556.1 - 1.9e-05 24.4 13.8 3e-05 23.8 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 OAJ03557.1 - 4.8e-20 72.1 0.9 9.2e-20 71.2 0.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ03557.1 - 6.7e-12 45.6 0.1 9e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ03557.1 - 2.2e-07 30.7 0.1 3.8e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 OAJ03557.1 - 1.5e-05 25.1 0.5 4.7e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ03557.1 - 2.7e-05 23.7 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAJ03557.1 - 0.037 14.0 0.1 0.081 12.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 OAJ03557.1 - 0.044 12.6 0.0 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 OAJ03557.1 - 0.064 12.5 0.6 0.098 11.8 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family PRELI PF04707.9 OAJ03564.1 - 3.1e-18 65.8 0.2 3.3e-07 29.9 0.0 3.3 3 0 0 3 3 3 3 PRELI-like family Hs1pro-1_N PF07231.7 OAJ03564.1 - 0.035 13.7 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Hs1pro-1 N-terminus DUF1279 PF06916.8 OAJ03565.1 - 5.3e-19 68.3 0.0 3.7e-18 65.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF241 PF03087.9 OAJ03565.1 - 0.19 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function ECH PF00378.15 OAJ03566.1 - 4.9e-20 71.6 0.1 3.2e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ03566.1 - 2.1e-09 37.5 0.2 0.0033 17.5 0.0 2.9 2 1 0 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region Pkinase PF00069.20 OAJ03567.1 - 1.2e-42 145.8 0.0 2.7e-24 85.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03567.1 - 3.7e-22 78.6 0.0 7.6e-11 41.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ03567.1 - 1.2e-07 31.0 0.0 7.2e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 OAJ03567.1 - 0.051 13.3 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0160 PF03690.8 OAJ03568.1 - 1.3e-123 412.4 0.0 1.9e-123 411.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.5 OAJ03568.1 - 8.9e-16 57.9 0.1 2.7e-11 43.2 0.1 3.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Zip PF02535.17 OAJ03569.1 - 0.57 9.1 6.5 0.077 11.9 1.5 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter TIP41 PF04176.8 OAJ03570.1 - 1.1e-43 148.6 0.0 7.2e-40 136.1 0.0 2.9 1 1 1 2 2 2 2 TIP41-like family COX14 PF14880.1 OAJ03571.1 - 0.0032 17.0 0.2 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF2530 PF10745.4 OAJ03571.1 - 0.073 13.0 0.2 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Pkinase PF00069.20 OAJ03574.1 - 2.6e-07 30.0 0.0 3.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 OAJ03574.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ03574.1 - 0.00028 19.8 0.0 0.00041 19.2 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 OAJ03574.1 - 0.021 13.8 1.2 0.038 13.0 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ03574.1 - 0.068 12.1 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like NUDIX PF00293.23 OAJ03575.1 - 4e-07 29.7 0.0 6.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-U1 PF06220.7 OAJ03576.1 - 6.3e-15 54.4 3.7 8.9e-15 53.9 2.6 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 OAJ03576.1 - 0.2 11.8 1.2 0.33 11.1 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Sec66 PF09802.4 OAJ03577.1 - 5.6e-49 166.1 0.1 7.3e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SWIB PF02201.13 OAJ03578.1 - 1.4e-16 59.9 0.0 2.9e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain WD40 PF00400.27 OAJ03579.1 - 1.2e-40 135.8 24.4 4.3e-08 32.7 0.0 10.9 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.7 OAJ03579.1 - 2.7e-14 53.0 0.0 8.8e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Dip2/Utp12 Family Nup160 PF11715.3 OAJ03579.1 - 0.00072 17.8 0.1 1.5 6.8 0.0 3.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 OAJ03579.1 - 0.0016 16.8 0.0 0.9 7.7 0.0 3.7 4 1 1 5 5 5 2 Cytochrome D1 heme domain eIF2A PF08662.6 OAJ03579.1 - 0.012 15.3 0.0 2.6 7.6 0.0 4.1 5 1 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 OAJ03579.1 - 0.031 13.7 0.2 3.4 7.3 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ03579.1 - 0.035 13.5 0.0 3.8 6.8 0.0 2.8 1 1 0 2 2 2 0 PQQ-like domain DUF1513 PF07433.6 OAJ03579.1 - 0.055 12.3 0.1 2.2 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.7 OAJ03579.1 - 0.46 10.2 2.5 10 5.9 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Alpha-amylase_C PF02806.13 OAJ03580.1 - 0.05 13.7 0.1 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Cytadhesin_P30 PF07271.6 OAJ03581.1 - 0.054 12.7 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 CMAS PF02353.15 OAJ03582.1 - 3.4e-33 114.8 0.3 1.5e-32 112.7 0.2 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 OAJ03582.1 - 3.1e-11 43.5 0.0 8.4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03582.1 - 9.1e-10 38.3 0.0 2.7e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03582.1 - 4.9e-08 32.8 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03582.1 - 2.1e-07 31.4 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ03582.1 - 3.5e-06 27.3 0.0 1e-05 25.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ03582.1 - 8e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ03582.1 - 9.9e-06 25.0 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 OAJ03582.1 - 0.0066 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 OAJ03582.1 - 0.064 12.4 0.1 0.27 10.3 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB DOT1 PF08123.8 OAJ03582.1 - 0.095 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 OAJ03582.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 OAJ03583.1 - 4e-18 65.2 46.8 4e-18 65.2 32.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ03583.1 - 0.047 13.4 0.6 0.047 13.4 0.4 3.2 2 1 0 2 2 2 0 MFS_1 like family Gram_pos_anchor PF00746.16 OAJ03583.1 - 0.22 11.3 0.2 0.22 11.3 0.1 4.7 8 0 0 8 8 8 0 Gram positive anchor Sld5 PF05916.6 OAJ03587.1 - 0.0021 18.3 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein zf-CCHC PF00098.18 OAJ03588.1 - 0.00011 21.9 2.9 0.00021 21.0 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle DnaJ PF00226.26 OAJ03589.1 - 5e-15 54.9 1.4 1e-14 53.9 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain XdhC_CoxI PF02625.11 OAJ03589.1 - 0.058 13.0 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 XdhC and CoxI family LcrG PF07216.7 OAJ03589.1 - 0.61 10.1 5.2 0.58 10.2 1.5 2.3 1 1 1 2 2 2 0 LcrG protein DMRL_synthase PF00885.14 OAJ03590.1 - 5.1e-42 142.9 0.0 1.6e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.5 OAJ03590.1 - 0.001 18.6 0.1 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding F-box-like PF12937.2 OAJ03591.1 - 2.1e-06 27.3 0.7 7.3e-06 25.6 0.5 2.0 1 0 0 1 1 1 1 F-box-like Mga PF05043.8 OAJ03591.1 - 0.038 14.2 0.1 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 Mga helix-turn-helix domain F-box PF00646.28 OAJ03591.1 - 2.8 7.7 5.1 2.6 7.7 1.4 2.6 2 1 0 2 2 2 0 F-box domain Transcrip_reg PF01709.15 OAJ03592.1 - 6.7e-56 189.0 0.0 3.2e-55 186.7 0.0 1.8 1 1 0 1 1 1 1 Transcriptional regulator Spore_III_AB PF09548.5 OAJ03592.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Picorna_P3A PF06363.6 OAJ03592.1 - 0.016 15.2 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 Picornaviridae P3A protein Transaldolase PF00923.14 OAJ03593.1 - 7.8e-98 327.1 0.4 8.8e-98 326.9 0.3 1.0 1 0 0 1 1 1 1 Transaldolase Imm31 PF15595.1 OAJ03593.1 - 0.092 12.5 0.2 0.19 11.4 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 31 Aminotran_1_2 PF00155.16 OAJ03594.1 - 2.9e-78 263.3 0.0 3.4e-78 263.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Urb2 PF10441.4 OAJ03595.1 - 2.4e-31 109.0 0.0 1.5e-30 106.4 0.0 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family Peptidase_S8 PF00082.17 OAJ03596.1 - 7.5e-51 172.9 0.0 1.1e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ03596.1 - 1.2e-06 28.8 0.1 1.9e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ03596.1 - 5.4e-05 22.8 0.0 0.00019 21.0 0.0 2.0 2 0 0 2 2 2 1 PA domain NPCBM_assoc PF10633.4 OAJ03596.1 - 0.031 14.3 0.3 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_A4 PF01828.12 OAJ03596.1 - 0.23 10.4 0.1 0.5 9.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase A4 family DUF89 PF01937.14 OAJ03597.1 - 5.7e-21 74.6 0.1 7.1e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 B56 PF01603.15 OAJ03599.1 - 4.6e-169 562.3 2.8 5.5e-169 562.1 1.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Hat1_N PF10394.4 OAJ03600.1 - 7.8e-34 117.0 0.0 1.8e-33 115.9 0.0 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 OAJ03600.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ03600.1 - 0.072 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PaaA_PaaC PF05138.7 OAJ03603.1 - 0.00046 19.2 0.7 0.51 9.2 0.0 2.3 2 0 0 2 2 2 2 Phenylacetic acid catabolic protein DUF952 PF06108.7 OAJ03603.1 - 0.008 16.0 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF952) NAPRTase PF04095.11 OAJ03603.1 - 0.04 13.1 0.5 13 4.9 0.0 3.0 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Phosphoprotein PF00922.12 OAJ03603.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 OAJ03606.1 - 6.3e-33 113.9 31.1 6.3e-33 113.9 21.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_kinase PF00696.23 OAJ03607.1 - 2.1e-36 125.7 0.0 2.6e-31 109.0 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 OAJ03607.1 - 4.8e-09 35.5 0.4 0.00015 21.1 0.0 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 OAJ03607.1 - 1.4e-06 27.7 1.6 3e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 ACT domain DUF77 PF01910.12 OAJ03608.1 - 8.6e-23 79.8 0.0 1.4e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 OAJ03608.1 - 0.0013 18.8 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 YKOF-related Family RQC PF09382.5 OAJ03609.1 - 6.9e-22 77.1 0.0 1.6e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 OAJ03609.1 - 1.6e-19 69.4 0.0 2.4e-18 65.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ03609.1 - 2.5e-19 69.3 0.0 7.2e-19 67.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 OAJ03609.1 - 1e-11 44.3 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.3 OAJ03609.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Sgs1 RecQ helicase PHA_gran_rgn PF09650.5 OAJ03609.1 - 0.03 14.4 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DUF1793 PF08760.6 OAJ03610.1 - 2.8e-66 222.5 0.5 5e-66 221.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 OAJ03610.1 - 0.013 14.6 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Ribosomal_S9 PF00380.14 OAJ03611.1 - 2.6e-35 121.2 0.0 5.6e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HD_3 PF13023.1 OAJ03612.1 - 2.3e-40 138.0 0.1 4.5e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 HD domain HD PF01966.17 OAJ03612.1 - 5.1e-05 23.2 0.1 0.00013 21.9 0.1 1.7 1 0 0 1 1 1 1 HD domain Zn_clus PF00172.13 OAJ03613.1 - 5.8e-08 32.5 8.0 9.8e-08 31.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ03613.1 - 1.9e-05 23.7 0.2 5.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PBP1_TM PF14812.1 OAJ03613.1 - 1.3 9.3 10.6 3.7 7.9 0.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Neur_chan_memb PF02932.11 OAJ03613.1 - 4.3 7.1 5.8 12 5.7 4.0 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 OAJ03613.1 - 5.3 5.7 12.3 9.5 4.9 8.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein EphA2_TM PF14575.1 OAJ03613.1 - 5.7 7.4 5.0 59 4.1 0.0 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LUC7 PF03194.10 OAJ03615.1 - 4.5e-72 242.6 4.1 4.5e-72 242.6 2.8 1.5 2 0 0 2 2 2 1 LUC7 N_terminus DUF4138 PF13595.1 OAJ03615.1 - 0.12 11.2 0.2 0.19 10.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Prenyltrans PF00432.16 OAJ03616.1 - 2.2e-39 132.6 9.9 2.8e-12 45.9 0.1 5.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ03616.1 - 3.3e-26 91.9 0.2 2.3e-13 50.5 0.0 3.7 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ03616.1 - 1.1e-07 31.8 0.0 0.016 15.2 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 OAJ03616.1 - 0.055 12.7 0.0 16 4.5 0.0 3.2 4 0 0 4 4 4 0 A-macroglobulin complement component WD40 PF00400.27 OAJ03617.1 - 4.3e-24 83.4 6.9 1e-07 31.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 OAJ03617.1 - 0.0005 18.0 1.4 0.028 12.2 0.6 2.2 2 0 0 2 2 2 2 IKI3 family eIF2A PF08662.6 OAJ03617.1 - 0.00066 19.4 0.2 0.046 13.4 0.2 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAJ03619.1 - 5.3e-42 140.2 10.7 1.8e-10 40.2 0.0 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat SGL PF08450.7 OAJ03619.1 - 0.024 14.0 0.1 0.22 10.8 0.0 2.3 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 OAJ03619.1 - 0.11 10.6 1.2 2.5 6.1 0.8 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 CcmD PF04995.9 OAJ03620.1 - 0.16 11.6 1.2 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Syndecan PF01034.15 OAJ03620.1 - 0.22 11.2 0.3 0.39 10.4 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Proteasome PF00227.21 OAJ03621.1 - 8.6e-50 168.6 0.1 1.1e-49 168.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.4 OAJ03621.1 - 0.008 16.0 0.2 0.58 10.1 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2188) Phos_pyr_kin PF08543.7 OAJ03622.1 - 2.9e-09 36.4 0.0 6.7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 OAJ03622.1 - 4.2e-08 32.6 0.1 2.3e-06 26.9 0.0 2.5 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Sterol-sensing PF12349.3 OAJ03623.1 - 1.4e-40 138.2 12.2 3.6e-40 136.9 8.5 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ03623.1 - 2e-13 49.2 3.7 2.9e-13 48.6 2.5 1.1 1 0 0 1 1 1 1 Patched family PQQ_2 PF13360.1 OAJ03623.1 - 0.011 15.2 0.2 0.036 13.5 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain 6PGD PF00393.14 OAJ03624.1 - 2.8e-114 381.2 0.0 3.5e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.15 OAJ03626.1 - 3.3e-17 62.8 0.1 5.1e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ03626.1 - 3.2e-10 40.3 2.2 1.1e-08 35.2 1.4 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ03626.1 - 0.00027 20.4 0.1 0.00045 19.7 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ03626.1 - 0.0011 18.7 0.0 0.06 13.0 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LAT PF15234.1 OAJ03627.1 - 0.11 12.0 2.9 0.12 11.8 2.0 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells Myc_N PF01056.13 OAJ03627.1 - 0.12 11.4 3.2 0.13 11.3 2.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region His_Phos_2 PF00328.17 OAJ03628.1 - 2.3e-71 240.9 0.1 3.2e-71 240.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 OAJ03628.1 - 1.4e-06 27.9 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ArgJ PF01960.13 OAJ03629.1 - 8.2e-124 412.9 0.1 1.3e-123 412.2 0.0 1.2 1 0 0 1 1 1 1 ArgJ family Hist_deacetyl PF00850.14 OAJ03630.1 - 1.1e-78 264.6 0.0 1.4e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1793 PF08760.6 OAJ03631.1 - 6.1e-58 195.4 0.0 1e-57 194.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Transposase_24 PF03004.9 OAJ03631.1 - 0.062 13.1 0.8 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Cys_Met_Meta_PP PF01053.15 OAJ03632.1 - 1.5e-151 504.0 0.0 1.7e-151 503.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 OAJ03632.1 - 7.8e-13 48.1 0.1 1.7e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAJ03632.1 - 4.1e-10 39.1 0.1 6.4e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ03632.1 - 2.3e-09 36.5 0.1 3.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 OAJ03632.1 - 2.8e-06 26.7 0.0 5e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 OAJ03632.1 - 0.00036 18.9 0.0 0.00052 18.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 OAJ03632.1 - 0.009 14.7 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 OAJ03632.1 - 0.056 11.9 0.0 0.078 11.4 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RVT_1 PF00078.22 OAJ03633.1 - 3e-24 85.5 0.0 6.5e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ03633.1 - 1.2e-22 80.2 0.0 9e-22 77.4 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Retrotrans_gag PF03732.12 OAJ03633.1 - 4.8e-11 42.5 1.4 1.9e-09 37.4 0.0 3.9 4 0 0 4 4 4 1 Retrotransposon gag protein Chromo PF00385.19 OAJ03633.1 - 1e-05 25.0 0.2 2.2e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.6 OAJ03633.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ03633.1 - 0.00065 20.1 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ03633.1 - 0.098 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease FA_desaturase PF00487.19 OAJ03635.1 - 2.3e-15 56.7 24.5 4e-15 55.9 17.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAJ03635.1 - 2.6e-14 52.7 0.0 5.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LETM1 PF07766.8 OAJ03636.1 - 3e-96 321.5 1.7 3e-96 321.5 1.2 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 OAJ03636.1 - 6.1e-05 23.0 0.2 0.00085 19.4 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 OAJ03636.1 - 0.00094 18.7 0.1 0.0069 15.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ03636.1 - 0.0062 15.7 1.0 1.9 8.0 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 OAJ03636.1 - 0.053 13.4 3.0 8.2 6.6 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain Neur_chan_memb PF02932.11 OAJ03636.1 - 6.7 6.5 13.2 0.61 9.9 0.8 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rot1 PF10681.4 OAJ03637.1 - 1.9e-60 203.8 2.9 2.4e-60 203.5 2.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal CN_hydrolase PF00795.17 OAJ03638.1 - 1.8e-25 89.4 0.0 2.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 OAJ03638.1 - 1.5e-23 82.9 0.0 1.3e-19 70.0 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 OAJ03638.1 - 0.094 12.1 0.0 0.25 10.8 0.0 1.6 1 1 0 1 1 1 0 Asparagine synthase LIP PF03583.9 OAJ03644.1 - 5.5e-56 189.9 0.1 7.2e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 OAJ03644.1 - 5.4e-05 22.9 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ03644.1 - 0.0015 18.4 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ03644.1 - 0.0034 16.6 0.1 0.041 13.0 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Cutinase PF01083.17 OAJ03644.1 - 0.015 15.0 0.2 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 Cutinase DUF2920 PF11144.3 OAJ03644.1 - 0.095 11.6 0.1 0.64 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) CUE PF02845.11 OAJ03645.1 - 1.4e-12 46.8 0.1 2.3e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 CUE domain DUF2235 PF09994.4 OAJ03646.1 - 2.9e-57 194.1 0.0 5.2e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CHAD PF05235.9 OAJ03646.1 - 0.0051 16.4 2.4 0.0099 15.4 1.7 1.5 1 0 0 1 1 1 1 CHAD domain DUF2235 PF09994.4 OAJ03647.1 - 6.8e-64 215.9 0.0 1e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tim17 PF02466.14 OAJ03648.1 - 6.5e-21 74.7 8.7 1.2e-20 73.8 6.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Med3 PF11593.3 OAJ03648.1 - 0.0052 16.0 2.8 0.008 15.4 1.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal AflR PF08493.5 OAJ03648.1 - 1.9 7.4 9.6 2.5 7.0 6.6 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein PAPS_reduct PF01507.14 OAJ03649.1 - 1.4e-18 67.3 0.0 4e-08 33.2 0.0 3.2 3 0 0 3 3 3 3 Phosphoadenosine phosphosulfate reductase family DUF2235 PF09994.4 OAJ03650.1 - 2e-67 227.4 0.0 2.8e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.4 OAJ03651.1 - 3.9e-58 197.0 0.0 1.2e-56 192.1 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ03651.1 - 0.053 13.2 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hepar_II_III PF07940.8 OAJ03652.1 - 1.3e-09 38.0 2.8 4.3e-09 36.3 0.4 2.4 2 0 0 2 2 2 1 Heparinase II/III-like protein BPL_LplA_LipB PF03099.14 OAJ03653.1 - 9.3e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family JmjC PF02373.17 OAJ03654.1 - 1.7e-08 34.6 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase DUF1875 PF08961.5 OAJ03654.1 - 0.0048 16.2 1.1 0.0076 15.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) ELH PF02323.10 OAJ03654.1 - 0.0079 15.3 3.2 0.014 14.5 2.2 1.3 1 0 0 1 1 1 1 Egg-laying hormone precursor DUF904 PF06005.7 OAJ03654.1 - 0.01 16.0 7.9 0.011 15.9 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) NUDE_C PF04880.8 OAJ03654.1 - 0.015 15.6 3.0 0.076 13.3 2.1 2.1 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region HALZ PF02183.13 OAJ03654.1 - 0.083 12.6 6.9 0.21 11.3 4.7 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper Chibby PF14645.1 OAJ03654.1 - 0.083 12.7 1.4 0.16 11.8 1.0 1.4 1 0 0 1 1 1 0 Chibby family CAF-1_p150 PF11600.3 OAJ03654.1 - 1.4 8.2 22.1 2.2 7.5 15.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 OAJ03654.1 - 2.3 7.2 8.5 3.2 6.7 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 OAJ03654.1 - 4 6.9 10.3 7 6.2 7.1 1.3 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 OAJ03654.1 - 9.1 5.8 7.9 14 5.1 5.5 1.2 1 0 0 1 1 1 0 IncA protein adh_short PF00106.20 OAJ03655.1 - 1.7e-28 99.6 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ03655.1 - 1.7e-22 80.3 0.0 2.1e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ03655.1 - 3e-13 49.8 0.0 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAJ03655.1 - 0.0023 17.1 0.1 0.035 13.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 OAJ03655.1 - 0.085 12.6 0.5 0.2 11.4 0.3 1.7 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 OAJ03655.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Init_tRNA_PT PF04179.7 OAJ03656.1 - 1.6e-100 337.1 0.0 2.2e-100 336.6 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase SPC25 PF06703.6 OAJ03657.1 - 1.7e-32 112.2 0.0 4.4e-32 110.9 0.0 1.6 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Mgm101p PF06420.7 OAJ03658.1 - 2e-85 284.3 0.0 2.6e-85 284.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 SPRY PF00622.23 OAJ03660.1 - 0.00012 22.1 0.0 0.0075 16.3 0.0 3.1 3 0 0 3 3 3 1 SPRY domain Svf1 PF08622.5 OAJ03661.1 - 1.1e-86 290.8 0.0 2.7e-86 289.5 0.0 1.6 1 1 0 1 1 1 1 Svf1-like Spc97_Spc98 PF04130.8 OAJ03662.1 - 5.2e-65 219.7 0.0 6.7e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family UNC-93 PF05978.11 OAJ03663.1 - 0.00058 19.3 4.7 0.00058 19.3 3.3 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 OAJ03663.1 - 0.00089 18.0 33.1 0.0021 16.8 22.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ComJ PF11033.3 OAJ03663.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) eIF3g PF12353.3 OAJ03664.1 - 7.8e-41 138.9 2.3 1.4e-40 138.1 1.6 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 OAJ03664.1 - 2.8e-18 65.2 0.0 4.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03664.1 - 3.7e-15 55.6 0.0 6.5e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03664.1 - 1.4e-08 34.4 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_ToxA PF11584.3 OAJ03664.1 - 0.0082 15.9 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 2 Proteinaceous host-selective toxin ToxA CTD_bind PF04818.8 OAJ03665.1 - 0.00028 21.0 0.0 0.024 14.8 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase II-binding domain. Dynamitin PF04912.9 OAJ03665.1 - 0.1 11.3 0.3 0.15 10.8 0.2 1.1 1 0 0 1 1 1 0 Dynamitin MFS_1 PF07690.11 OAJ03666.1 - 5.8e-32 110.7 12.3 9.1e-32 110.1 8.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CorA PF01544.13 OAJ03667.1 - 1.5e-44 152.2 0.2 2.1e-44 151.7 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ACT_4 PF13291.1 OAJ03667.1 - 0.15 12.3 0.1 0.39 11.0 0.1 1.7 1 0 0 1 1 1 0 ACT domain GHMP_kinases_N PF00288.21 OAJ03668.1 - 2.9e-10 40.0 5.6 2.9e-10 40.0 3.8 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ03668.1 - 0.00057 20.0 0.1 0.0016 18.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal SH3_9 PF14604.1 OAJ03669.1 - 7.7e-31 105.4 3.4 1.5e-14 53.2 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 OAJ03669.1 - 1.4e-26 91.5 4.5 1.1e-12 47.0 0.1 2.9 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 OAJ03669.1 - 1.1e-16 60.0 0.0 1.1e-06 27.9 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 OAJ03669.1 - 9.6e-13 48.1 0.0 1.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Requiem_N PF14051.1 OAJ03670.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. PNRC PF15365.1 OAJ03671.1 - 7.1e-06 25.9 0.9 7.1e-06 25.9 0.6 3.7 5 1 0 5 5 5 1 Proline-rich nuclear receptor coactivator SPT6_acidic PF14632.1 OAJ03671.1 - 0.75 10.0 4.6 10 6.3 1.6 2.4 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Telomere_Sde2 PF13019.1 OAJ03672.1 - 2.2e-39 134.7 0.0 2.2e-39 134.7 0.0 1.9 2 1 0 2 2 2 1 Telomere stability and silencing Packaging_FI PF14000.1 OAJ03672.1 - 0.091 12.9 5.3 0.18 12.0 3.6 1.6 1 1 0 1 1 1 0 DNA packaging protein FI TPR_14 PF13428.1 OAJ03672.1 - 0.12 13.0 1.3 0.42 11.3 0.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat GTSE1_N PF15259.1 OAJ03672.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.4 1 1 2 3 3 3 0 G-2 and S-phase expressed 1 Raptor_N PF14538.1 OAJ03673.1 - 4e-51 172.9 0.0 4e-51 172.9 0.0 1.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 OAJ03673.1 - 4.8e-08 32.5 3.4 1.2 9.1 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.1 OAJ03673.1 - 0.064 13.5 1.2 0.3 11.3 0.0 2.7 2 1 1 3 3 3 0 HEAT repeats BBS2_Mid PF14783.1 OAJ03673.1 - 0.07 12.9 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 OAJ03673.1 - 0.097 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 OAJ03673.1 - 0.15 12.5 3.6 23 5.6 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.17 OAJ03673.1 - 0.21 11.7 8.3 5.1 7.4 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat TFIIA PF03153.8 OAJ03673.1 - 8.2 6.2 13.7 15 5.3 9.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PCI PF01399.22 OAJ03674.1 - 4.7e-17 62.2 0.1 1.2e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 OAJ03674.1 - 1.6e-09 37.6 0.0 3.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FimP PF09766.4 OAJ03674.1 - 0.0014 17.7 0.6 0.0022 17.1 0.4 1.3 1 0 0 1 1 1 1 Fms-interacting protein FeoC PF09012.5 OAJ03674.1 - 0.0037 16.9 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator TPR_11 PF13414.1 OAJ03674.1 - 0.045 13.3 2.3 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.1 OAJ03674.1 - 0.048 14.3 2.0 0.1 13.3 0.1 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03674.1 - 0.27 11.2 4.3 12 6.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CLASP_N PF12348.3 OAJ03675.1 - 9.9e-66 221.3 1.9 1.7e-53 181.2 0.0 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.17 OAJ03675.1 - 1e-07 31.4 3.7 0.043 13.9 0.1 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 OAJ03675.1 - 0.00051 20.2 22.2 0.021 15.1 0.9 6.0 4 1 1 5 5 5 2 HEAT repeats Arm PF00514.18 OAJ03675.1 - 0.048 13.5 1.1 2.4 8.1 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 OAJ03675.1 - 1.2 9.7 12.6 3.6 8.2 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat Acetyltransf_1 PF00583.19 OAJ03676.1 - 1.2e-13 50.8 0.0 1.7e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ03676.1 - 1.8e-06 28.0 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 OAJ03676.1 - 6.5e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ03676.1 - 0.00015 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ03676.1 - 0.00076 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 OAJ03676.1 - 0.00086 19.4 0.0 0.001 19.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ03676.1 - 0.00087 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ03676.1 - 0.0047 16.7 0.0 0.027 14.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ03676.1 - 0.016 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GHMP_kinases_N PF00288.21 OAJ03677.1 - 8e-13 48.2 0.1 2.2e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ03677.1 - 0.0015 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF775 PF05603.7 OAJ03678.1 - 3.7e-35 121.2 0.0 4.2e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) OAD_gamma PF04277.8 OAJ03684.1 - 0.037 14.3 1.3 0.38 11.1 0.1 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FAM70 PF14967.1 OAJ03684.1 - 9.8 5.2 10.6 15 4.6 7.3 1.2 1 0 0 1 1 1 0 FAM70 protein Utp11 PF03998.8 OAJ03685.1 - 4.7e-51 173.9 8.5 7.4e-51 173.3 5.9 1.4 1 1 0 1 1 1 1 Utp11 protein Flu_NS2 PF00601.14 OAJ03685.1 - 0.19 11.9 0.6 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) UPF0197 PF05251.7 OAJ03686.1 - 0.00029 21.0 1.0 0.00038 20.6 0.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Fig1 PF12351.3 OAJ03686.1 - 0.038 13.8 0.4 0.039 13.8 0.3 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF308 PF03729.8 OAJ03686.1 - 0.053 13.5 2.0 0.072 13.0 1.4 1.2 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) Claudin_2 PF13903.1 OAJ03686.1 - 0.067 12.8 0.9 0.082 12.6 0.6 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SCP2 PF02036.12 OAJ03687.1 - 5.3e-26 90.8 1.2 6e-26 90.7 0.8 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 OAJ03687.1 - 0.00017 21.5 0.7 0.00039 20.4 0.5 1.6 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal DUF1700 PF08006.6 OAJ03687.1 - 0.079 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ArfGap PF01412.13 OAJ03689.1 - 6.3e-41 138.8 0.1 6.3e-41 138.8 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AIF_C PF14721.1 OAJ03689.1 - 0.023 14.9 6.5 0.023 14.9 4.5 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hira PF07569.6 OAJ03689.1 - 0.029 13.5 3.7 0.054 12.6 2.6 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split OmpH PF03938.9 OAJ03689.1 - 0.046 13.6 28.2 0.087 12.7 19.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RED_N PF07808.8 OAJ03689.1 - 1 8.5 14.4 2.1 7.4 10.0 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region Macro PF01661.16 OAJ03692.1 - 2.8e-41 140.1 0.1 4e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Macro domain Aminotran_3 PF00202.16 OAJ03693.1 - 2.2e-106 355.5 0.0 3e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 OAJ03693.1 - 0.0037 16.4 0.0 0.015 14.4 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ03693.1 - 0.036 13.0 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II DUF3446 PF11928.3 OAJ03693.1 - 0.32 11.1 4.9 0.094 12.9 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MTBP_C PF14920.1 OAJ03694.1 - 0.22 10.9 5.2 0.068 12.6 1.4 1.8 2 0 0 2 2 2 0 MDM2-binding ABC_membrane_2 PF06472.10 OAJ03695.1 - 1.9e-100 335.6 5.1 2.5e-100 335.2 3.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 OAJ03695.1 - 4.8e-20 72.2 0.0 1.9e-19 70.3 0.0 2.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 OAJ03695.1 - 0.00026 21.0 0.1 0.00065 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 OAJ03695.1 - 0.0063 16.8 0.2 0.038 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAJ03695.1 - 0.015 14.5 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ03695.1 - 0.021 14.7 0.0 0.078 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 OAJ03695.1 - 0.025 14.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ03695.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ03695.1 - 0.045 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF815 PF05673.8 OAJ03695.1 - 0.075 11.9 0.0 0.19 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RRM_1 PF00076.17 OAJ03696.1 - 2.3e-34 116.8 0.0 3.5e-13 48.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03696.1 - 1.6e-29 101.7 0.0 1.8e-10 40.6 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03696.1 - 4.6e-19 68.0 0.0 2.3e-06 27.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ERG2_Sigma1R PF04622.7 OAJ03697.1 - 2.1e-82 275.5 0.0 2.5e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein TFIIS_C PF01096.13 OAJ03698.1 - 2.2e-13 49.6 3.0 2.2e-13 49.6 2.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 OAJ03698.1 - 0.00011 21.7 2.7 0.00058 19.4 0.5 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 OAJ03698.1 - 0.0072 16.0 0.2 0.0072 16.0 0.1 2.2 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_LEF5_C PF11792.3 OAJ03698.1 - 0.015 14.6 0.8 0.015 14.6 0.5 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain OrfB_Zn_ribbon PF07282.6 OAJ03698.1 - 0.026 14.1 1.4 0.075 12.7 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 OAJ03698.1 - 0.041 13.6 0.2 0.041 13.6 0.2 2.3 2 1 0 2 2 2 0 Double zinc ribbon DUF1062 PF06353.7 OAJ03698.1 - 0.055 13.6 1.2 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) IBR PF01485.16 OAJ03698.1 - 0.069 13.0 6.4 0.96 9.3 0.2 2.4 2 1 0 2 2 2 0 IBR domain DNA_RNApol_7kD PF03604.8 OAJ03698.1 - 0.07 12.6 3.6 1.2 8.6 0.7 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PHD PF00628.24 OAJ03698.1 - 0.58 9.8 4.2 18 5.1 1.6 2.9 2 1 1 3 3 3 0 PHD-finger DUF3133 PF11331.3 OAJ03698.1 - 0.72 9.4 3.9 11 5.7 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3133) zf-ribbon_3 PF13248.1 OAJ03698.1 - 0.85 8.9 5.0 4.4 6.6 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 OAJ03698.1 - 1.6 8.4 7.2 4.4 6.9 1.2 3.0 2 1 1 3 3 3 0 zinc-ribbon domain Prok-RING_1 PF14446.1 OAJ03698.1 - 2.1 8.1 7.2 0.2 11.3 0.4 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_4 PF13717.1 OAJ03698.1 - 2.2 8.0 7.4 6.8 6.4 1.5 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Rpr2 PF04032.11 OAJ03698.1 - 8.8 6.2 7.0 5e+02 0.6 4.9 2.8 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain BcrAD_BadFG PF01869.15 OAJ03699.1 - 4.3e-08 32.7 0.0 1.7e-07 30.8 0.0 2.0 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MFS_1 PF07690.11 OAJ03700.1 - 6e-32 110.7 37.0 9.3e-32 110.0 25.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 OAJ03700.1 - 0.26 9.3 11.4 0.026 12.6 1.2 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ABC1 PF03109.11 OAJ03701.1 - 3.8e-22 78.4 0.0 2.5e-14 53.2 0.0 2.4 2 0 0 2 2 2 2 ABC1 family DNA_pol_viral_N PF00242.12 OAJ03701.1 - 5 6.0 5.7 7.2 5.5 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Asp PF00026.18 OAJ03702.1 - 2.9e-40 138.4 0.0 5.2e-40 137.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ03702.1 - 3.9e-10 39.9 1.3 8.6e-10 38.7 0.4 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ03702.1 - 0.025 15.0 0.1 4.2 7.9 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease Sugar_tr PF00083.19 OAJ03703.1 - 2.2e-82 277.0 22.7 2.5e-82 276.8 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ03703.1 - 1e-24 86.9 25.3 1e-24 86.9 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ03703.1 - 9.4e-05 20.8 0.7 9.4e-05 20.8 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Romo1 PF10247.4 OAJ03703.1 - 3.2 8.0 10.4 0.14 12.3 0.7 2.7 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DSPc PF00782.15 OAJ03705.1 - 1.3e-27 96.0 0.0 2.2e-21 75.8 0.0 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ03705.1 - 0.00024 20.5 0.0 0.0012 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ03705.1 - 0.11 12.5 0.1 0.88 9.6 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate Amino_oxidase PF01593.19 OAJ03706.1 - 7e-61 206.6 0.1 1.9e-60 205.2 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ03706.1 - 8.7e-11 41.6 0.1 2.2e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ03706.1 - 6.5e-09 35.1 0.1 3.3e-08 32.8 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ03706.1 - 0.0089 15.8 0.0 0.044 13.5 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 OAJ03706.1 - 0.01 15.7 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ03706.1 - 0.01 16.2 0.4 3.2 8.2 0.1 3.2 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ03706.1 - 0.011 14.8 0.1 0.025 13.6 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 OAJ03706.1 - 0.012 14.5 0.3 0.023 13.5 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 OAJ03706.1 - 0.031 14.3 0.1 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ03706.1 - 0.21 10.4 0.0 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 OAJ03706.1 - 0.24 10.2 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_32N PF00251.15 OAJ03707.1 - 1.6e-21 76.9 0.6 9.7e-21 74.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ03707.1 - 1.6e-05 25.1 0.1 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Ribosomal_S6 PF01250.12 OAJ03707.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S6 IF-2B PF01008.12 OAJ03708.1 - 4e-61 206.4 0.0 5.5e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DOT1 PF08123.8 OAJ03711.1 - 1.6e-65 220.2 0.0 2.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 OAJ03711.1 - 0.018 15.0 0.1 0.071 13.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Dicty_REP PF05086.7 OAJ03711.1 - 3.8 5.1 8.8 5.8 4.5 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pantoate_ligase PF02569.10 OAJ03712.1 - 7e-79 264.4 0.0 3.4e-78 262.2 0.0 2.0 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase PUA PF01472.15 OAJ03714.1 - 2.3e-15 56.0 0.0 3.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain MgtE PF01769.11 OAJ03715.1 - 2.8e-20 72.9 34.5 7e-09 36.0 0.3 5.2 6 0 0 6 6 6 4 Divalent cation transporter DDE_3 PF13358.1 OAJ03716.1 - 6.5e-32 110.3 0.0 9.9e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ03716.1 - 2.4e-06 26.9 0.0 6.6e-05 22.3 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ03716.1 - 3e-05 24.7 0.7 0.00012 22.7 0.0 2.5 3 0 0 3 3 3 1 Homeodomain-like domain rve PF00665.21 OAJ03716.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.6 OAJ03716.1 - 0.00028 19.7 0.0 0.044 12.5 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 OAJ03716.1 - 0.004 17.2 0.1 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.21 OAJ03718.1 - 4.3e-07 30.0 0.1 1.7e-06 28.1 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain CPSase_L_D3 PF02787.14 OAJ03718.1 - 0.00051 19.8 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_23 PF13384.1 OAJ03718.1 - 0.0023 17.4 0.3 0.0093 15.5 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain PHD PF00628.24 OAJ03719.1 - 0.00025 20.6 9.9 0.00025 20.6 6.8 2.3 2 0 0 2 2 2 1 PHD-finger PHD_3 PF13922.1 OAJ03719.1 - 1.2 9.3 8.3 0.51 10.6 3.0 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx OMPdecase PF00215.19 OAJ03720.1 - 1e-73 247.4 0.1 1.3e-73 247.1 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2508 PF10704.4 OAJ03720.1 - 0.12 12.5 0.3 0.51 10.5 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) VPS9 PF02204.13 OAJ03721.1 - 3.9e-31 107.1 0.1 7.1e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Acetyltransf_1 PF00583.19 OAJ03722.1 - 3e-12 46.4 0.0 4.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ03722.1 - 4.3e-05 23.6 0.2 8.9e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ03722.1 - 0.00054 19.6 0.0 0.00097 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ03722.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ03722.1 - 0.044 13.9 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Elf1 PF05129.8 OAJ03723.1 - 3.2e-25 87.6 0.7 3.8e-25 87.4 0.5 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-met PF12874.2 OAJ03727.1 - 3.4e-06 27.0 1.6 4.3e-06 26.7 0.6 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Glyco_transf_20 PF00982.16 OAJ03728.1 - 4.1e-140 467.4 0.0 2.8e-129 431.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ03728.1 - 1.2e-77 260.0 0.0 2.1e-77 259.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 OAJ03728.1 - 8.2e-06 25.5 0.0 0.0053 16.3 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 OAJ03728.1 - 0.0022 17.3 1.0 0.0069 15.7 0.1 2.2 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase ATP_transf PF09830.4 OAJ03729.1 - 6.2e-13 48.3 0.0 1.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 OAJ03729.1 - 0.025 15.1 0.0 0.19 12.2 0.0 2.3 2 1 0 2 2 2 0 HIT domain Tbf5 PF06331.7 OAJ03730.1 - 8.3e-23 79.9 0.1 8.8e-23 79.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 FlbD PF06289.6 OAJ03730.1 - 0.056 12.8 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar protein (FlbD) NAD_binding_9 PF13454.1 OAJ03731.1 - 0.055 13.2 0.1 0.76 9.5 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ03731.1 - 0.063 13.3 0.2 3.3 7.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ03731.1 - 0.15 12.5 0.2 1.4 9.4 0.1 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.16 OAJ03735.1 - 4.4e-49 166.5 0.1 7.4e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 OAJ03735.1 - 3.4e-12 46.3 0.1 6.2e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ03735.1 - 4.6e-09 36.5 1.8 9.6e-09 35.4 1.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 OAJ03735.1 - 0.00023 20.5 0.1 0.0004 19.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase COesterase PF00135.23 OAJ03735.1 - 0.016 13.9 1.6 0.045 12.4 0.7 1.9 2 0 0 2 2 2 0 Carboxylesterase family PD40 PF07676.7 OAJ03735.1 - 0.018 14.7 0.6 0.18 11.5 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AXE1 PF05448.7 OAJ03735.1 - 0.055 11.9 1.7 3.3 6.1 1.1 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Adaptin_N PF01602.15 OAJ03736.1 - 4.5e-99 332.1 10.9 7e-99 331.5 7.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 OAJ03736.1 - 1.9e-67 224.8 0.0 5.5e-67 223.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 OAJ03736.1 - 2.5e-62 208.6 0.2 6.2e-62 207.4 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 OAJ03736.1 - 2.1e-13 50.3 7.5 8.9e-05 22.6 0.0 5.5 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 OAJ03736.1 - 1.9e-09 37.6 8.1 0.002 17.9 0.0 5.1 2 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ03736.1 - 4e-07 29.5 0.2 0.0034 17.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 OAJ03736.1 - 0.0014 19.0 3.5 1.5 9.3 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat ParcG PF10274.4 OAJ03736.1 - 0.014 15.3 0.7 0.69 9.7 0.0 2.8 2 1 1 3 3 3 0 Parkin co-regulated protein TORC_C PF12886.2 OAJ03736.1 - 0.17 12.0 2.4 2.5 8.3 0.2 3.0 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus Dabb PF07876.7 OAJ03737.1 - 1.8e-15 57.1 0.1 2.1e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Aminotran_3 PF00202.16 OAJ03738.1 - 2.7e-76 256.6 0.0 3.6e-76 256.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DAO PF01266.19 OAJ03739.1 - 2.4e-48 164.8 2.0 2.7e-48 164.6 1.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ03739.1 - 1.1e-07 32.1 0.0 0.029 14.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ03739.1 - 6.7e-05 22.8 0.0 0.003 17.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ03739.1 - 0.00032 20.6 0.4 0.00079 19.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAJ03739.1 - 0.0023 16.6 0.4 0.85 8.1 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Mqo PF06039.10 OAJ03739.1 - 0.0056 14.9 0.0 0.72 7.9 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 OAJ03739.1 - 0.007 15.4 0.4 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 OAJ03739.1 - 0.021 13.7 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.14 OAJ03739.1 - 0.025 13.7 0.1 0.66 9.0 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.1 OAJ03739.1 - 0.032 14.0 0.7 0.35 10.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ03739.1 - 0.043 12.9 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family DUF2106 PF09879.4 OAJ03740.1 - 0.023 14.0 0.3 0.04 13.2 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Mito_carr PF00153.22 OAJ03741.1 - 1.3e-48 162.6 6.3 1.5e-16 59.8 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 OAJ03742.1 - 5.1e-06 26.0 0.0 9.7e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03742.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) N2227 PF07942.7 OAJ03742.1 - 0.52 9.2 2.7 0.69 8.8 0.0 2.0 2 0 0 2 2 2 0 N2227-like protein BTB PF00651.26 OAJ03743.1 - 3.9e-15 55.8 0.1 1.7e-10 40.8 0.0 3.5 3 0 0 3 3 3 3 BTB/POZ domain CAP_GLY PF01302.20 OAJ03743.1 - 2.9e-08 33.3 0.0 1.2e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 CAP-Gly domain Pkinase PF00069.20 OAJ03744.1 - 1e-73 247.6 0.0 1.5e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03744.1 - 7.6e-42 143.1 0.0 1.4e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 OAJ03744.1 - 9.1e-18 64.0 0.0 2.1e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 OAJ03744.1 - 5.4e-08 32.1 0.0 3.3e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like TerB-C PF15615.1 OAJ03744.1 - 0.029 14.6 3.5 0.1 12.8 0.0 3.0 3 0 0 3 3 3 0 TerB-C domain Kdo PF06293.9 OAJ03744.1 - 0.073 12.1 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP6A_N PF04406.9 OAJ03745.1 - 2.1e-14 52.9 0.0 4.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Velvet PF11754.3 OAJ03746.1 - 7.8e-16 58.2 0.1 5.5e-15 55.5 0.1 2.0 1 1 0 1 1 1 1 Velvet factor zf-UBR PF02207.15 OAJ03747.1 - 9.9e-14 50.8 9.9 9.9e-14 50.8 6.8 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 OAJ03747.1 - 0.00016 21.3 3.6 0.00016 21.3 2.5 3.7 4 0 0 4 4 4 1 PHD-finger RAP1 PF07218.6 OAJ03747.1 - 1.5 6.7 2.9 2.5 6.1 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sel1 PF08238.7 OAJ03749.1 - 7e-36 121.8 27.8 2e-06 28.2 0.1 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 OAJ03749.1 - 0.61 10.6 4.6 3 8.4 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat UCH PF00443.24 OAJ03750.1 - 5.7e-40 137.1 0.0 1e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ03750.1 - 9.9e-12 44.8 0.0 3.4e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SUZ PF12752.2 OAJ03751.1 - 7.2e-11 42.4 3.0 7.2e-11 42.4 2.0 7.1 8 0 0 8 8 8 2 SUZ domain R3H PF01424.17 OAJ03751.1 - 2.2e-07 30.4 0.0 4.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain Chromo PF00385.19 OAJ03753.1 - 2.7e-15 55.7 3.1 2.7e-15 55.7 2.2 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 OAJ03753.1 - 3.2e-09 36.4 0.0 2.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain tRNA-synt_2b PF00587.20 OAJ03754.1 - 2.8e-64 215.8 0.0 4.6e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ03754.1 - 3e-21 75.1 0.0 8.4e-21 73.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain DUF4415 PF14384.1 OAJ03754.1 - 0.018 15.1 0.3 0.056 13.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4415) Ribosomal_60s PF00428.14 OAJ03754.1 - 9 6.7 23.1 0.84 10.0 6.0 2.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein PCMT PF01135.14 OAJ03755.1 - 8.8e-64 214.8 0.0 8.4e-63 211.6 0.0 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 OAJ03755.1 - 0.0011 19.4 0.0 0.013 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03755.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03755.1 - 0.037 13.7 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03755.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DNA_ligase_A_M PF01068.16 OAJ03756.1 - 1.5e-17 63.6 0.1 9.1e-08 31.7 0.0 3.7 2 2 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ03756.1 - 2.2e-05 24.3 0.1 0.0052 16.6 0.0 3.5 3 1 0 3 3 3 1 DNA ligase N terminus zf-H2C2_2 PF13465.1 OAJ03757.1 - 4.8e-23 80.2 13.0 7.8e-06 25.9 0.5 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ03757.1 - 2.6e-20 71.4 21.6 9.6e-05 22.5 1.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ03757.1 - 2.8e-12 46.0 20.2 0.00096 19.3 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ03757.1 - 0.0027 17.5 11.1 0.11 12.4 0.6 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-TRAF PF02176.13 OAJ03757.1 - 0.02 15.2 6.4 0.046 14.1 0.3 2.8 1 1 2 3 3 3 0 TRAF-type zinc finger Nop14 PF04147.7 OAJ03757.1 - 0.84 7.4 12.1 1.3 6.8 8.4 1.1 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 OAJ03757.1 - 1 9.9 14.6 0.052 14.1 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-met PF12874.2 OAJ03757.1 - 3.2 8.0 14.2 5.5 7.3 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Cwf_Cwc_15 PF04889.7 OAJ03757.1 - 5.5 6.6 11.4 0.41 10.3 3.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PIG-H PF10181.4 OAJ03758.1 - 3.7e-06 26.4 0.2 3.1e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component FA_desaturase PF00487.19 OAJ03763.1 - 5.2e-33 114.5 16.9 2.4e-32 112.4 11.7 2.0 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 OAJ03763.1 - 1.5e-08 34.3 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Slx4 PF09494.5 OAJ03764.1 - 9.6e-10 38.0 0.1 9.3e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Slx4 endonuclease ABC1 PF03109.11 OAJ03765.1 - 7.7e-18 64.5 0.1 2.4e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 ABC1 family Mago-bind PF09282.5 OAJ03766.1 - 2.2e-13 49.4 1.9 5.4e-13 48.2 1.3 1.7 1 0 0 1 1 1 1 Mago binding NOA36 PF06524.7 OAJ03766.1 - 0.16 11.2 5.5 0.23 10.7 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein eIF3_subunit PF08597.5 OAJ03766.1 - 1.2 8.5 13.9 0.42 10.1 7.1 1.9 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit Nop14 PF04147.7 OAJ03766.1 - 1.7 6.4 7.6 2.1 6.1 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family FAD_binding_4 PF01565.18 OAJ03767.1 - 6.5e-38 129.3 3.2 6.9e-18 64.4 0.2 3.0 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.7 OAJ03767.1 - 1.9e-12 46.8 0.2 9.8e-12 44.5 0.3 2.2 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 OAJ03767.1 - 0.072 12.2 0.1 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding M_domain PF12938.2 OAJ03767.1 - 0.11 12.3 6.2 3.6 7.3 0.5 2.5 2 0 0 2 2 2 0 M domain of GW182 Paramyx_P_V_C PF03210.8 OAJ03767.1 - 0.27 11.0 0.0 0.47 10.3 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal CAP59_mtransfer PF11735.3 OAJ03769.1 - 1.1e-64 218.0 0.0 9.9e-64 214.8 0.0 2.0 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PBP1_TM PF14812.1 OAJ03769.1 - 3.7 7.9 10.1 12 6.3 7.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF952 PF06108.7 OAJ03770.1 - 3.3e-11 42.8 0.0 5e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mob1_phocein PF03637.12 OAJ03771.1 - 1.2e-55 187.8 0.8 1.6e-55 187.5 0.6 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_4 PF00953.16 OAJ03772.1 - 1e-30 106.6 6.6 2.2e-30 105.5 4.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 Fasciclin PF02469.17 OAJ03773.1 - 2.8e-29 101.7 7.3 1.4e-21 76.8 1.2 2.3 2 0 0 2 2 2 2 Fasciclin domain DnaJ PF00226.26 OAJ03774.1 - 2.7e-10 39.8 0.2 3.6e-09 36.2 0.0 2.8 3 0 0 3 3 3 1 DnaJ domain Cullin PF00888.17 OAJ03775.1 - 4.2e-174 580.3 5.1 5.5e-174 579.9 3.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ03775.1 - 1.2e-27 95.5 1.4 2.7e-27 94.3 0.9 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_27 PF13463.1 OAJ03775.1 - 0.002 18.4 0.0 3.7 7.9 0.0 2.9 2 0 0 2 2 2 2 Winged helix DNA-binding domain HTH_IclR PF09339.5 OAJ03775.1 - 0.0038 16.7 0.3 0.046 13.3 0.1 2.4 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_20 PF12840.2 OAJ03775.1 - 0.084 12.6 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Ubie_methyltran PF01209.13 OAJ03776.1 - 4.4e-71 238.6 0.0 1.6e-37 128.8 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 OAJ03776.1 - 9.7e-11 42.0 0.0 1.8e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ03776.1 - 3.5e-10 40.2 0.0 4e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ03776.1 - 2e-08 33.9 0.0 2.6e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03776.1 - 1.4e-07 31.3 0.0 2.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ03776.1 - 9.7e-06 25.8 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03776.1 - 1.3e-05 25.7 0.0 2.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03776.1 - 7e-05 22.8 0.0 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 OAJ03776.1 - 0.015 14.8 0.0 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase MTS PF05175.9 OAJ03776.1 - 0.058 12.7 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_transf_90 PF05686.7 OAJ03776.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 GPI-anchored PF10342.4 OAJ03777.1 - 2.8e-11 43.7 2.0 3.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TPR_2 PF07719.12 OAJ03778.1 - 4.9e-08 32.3 2.2 0.14 12.0 0.6 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ03778.1 - 2.5e-06 27.9 6.0 0.02 15.5 0.8 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ03778.1 - 7e-05 23.1 11.8 0.18 12.5 1.1 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03778.1 - 0.00011 21.7 0.3 0.26 10.9 0.2 3.5 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 OAJ03778.1 - 0.00017 21.0 0.7 3.7 7.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ03778.1 - 0.00087 19.5 7.0 8.3 6.8 0.3 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ03778.1 - 0.0084 15.6 1.7 4 7.1 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ03778.1 - 0.013 15.6 2.5 26 5.3 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ03778.1 - 0.055 13.9 3.4 36 5.1 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ03778.1 - 0.46 10.4 2.4 21 5.1 0.1 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 OAJ03779.1 - 5e-19 68.1 0.3 1.2e-18 66.9 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ03779.1 - 2.2e-12 46.6 0.4 4.2e-12 45.7 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 OAJ03779.1 - 0.03 13.4 0.1 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MFS_1 PF07690.11 OAJ03780.1 - 1.1e-28 100.0 25.9 1.1e-28 100.0 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ03780.1 - 2.2e-08 33.1 8.8 2.2e-08 33.1 6.1 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ03780.1 - 0.0086 14.3 6.6 0.016 13.3 4.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 OAJ03780.1 - 0.027 12.5 0.8 0.04 12.0 0.5 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Use1 PF09753.4 OAJ03780.1 - 1.3 8.4 2.3 2 7.7 1.6 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 P5-ATPase PF12409.3 OAJ03780.1 - 1.7 8.4 4.0 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 P5-type ATPase cation transporter Peptidase_C48 PF02902.14 OAJ03781.1 - 2.1e-25 89.6 0.1 1.2e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain F-actin_cap_A PF01267.12 OAJ03782.1 - 1.2e-63 214.7 0.0 1.7e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PQ-loop PF04193.9 OAJ03784.1 - 9.4e-24 82.7 0.8 1.6e-13 50.0 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 OAJ03784.1 - 0.038 14.4 2.7 0.05 14.0 1.4 1.5 1 1 0 1 1 1 0 ER lumen protein retaining receptor ABA_GPCR PF12430.3 OAJ03784.1 - 0.052 12.6 1.3 0.29 10.2 0.2 2.2 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor MtN3_slv PF03083.11 OAJ03784.1 - 0.38 10.6 3.8 0.32 10.8 0.5 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Zn_clus PF00172.13 OAJ03785.1 - 0.00084 19.1 11.1 0.0015 18.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IncA PF04156.9 OAJ03786.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S10 PF00450.17 OAJ03787.1 - 9e-90 301.7 0.0 2e-88 297.3 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ03787.1 - 0.022 14.6 0.2 0.3 10.9 0.1 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family TPR_MLP1_2 PF07926.7 OAJ03788.1 - 7.8e-23 80.6 15.3 7.8e-23 80.6 10.6 18.2 7 4 11 18 18 18 4 TPR/MLP1/MLP2-like protein ADIP PF11559.3 OAJ03788.1 - 0.00084 19.2 17.9 0.00084 19.2 12.4 18.9 9 4 11 20 20 20 2 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 OAJ03788.1 - 0.0041 16.9 6.2 0.0041 16.9 4.3 15.5 4 4 12 16 16 16 2 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.7 OAJ03788.1 - 0.093 12.5 48.8 1.2 9.1 4.7 10.6 9 0 0 9 9 9 0 Viral A-type inclusion protein repeat HA2 PF04408.18 OAJ03790.1 - 3.6e-24 84.7 1.2 1.2e-23 83.0 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ03790.1 - 3.9e-24 84.6 0.0 1.8e-23 82.5 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ03790.1 - 4.2e-14 52.1 0.0 9.5e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ03790.1 - 1.8e-06 27.5 0.0 4.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PWI PF01480.12 OAJ03790.1 - 0.00031 20.7 0.0 0.00072 19.6 0.0 1.7 1 0 0 1 1 1 1 PWI domain AAA_22 PF13401.1 OAJ03790.1 - 0.00032 20.8 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ03790.1 - 0.0031 16.4 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 OAJ03790.1 - 0.0093 15.4 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 OAJ03790.1 - 0.011 15.5 1.4 0.45 10.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 OAJ03790.1 - 0.023 14.5 0.0 9.4 6.0 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ03790.1 - 0.072 12.8 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 OAJ03790.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 OAJ03790.1 - 0.25 11.6 2.3 0.42 10.9 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.1 OAJ03790.1 - 1.5 9.1 0.0 1.5 9.1 0.0 3.2 2 1 0 2 2 1 0 AAA domain Metallophos PF00149.23 OAJ03791.1 - 5.1e-43 146.8 0.9 6.3e-43 146.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PrmA PF06325.8 OAJ03792.1 - 2.3e-09 36.7 0.0 4.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 OAJ03792.1 - 3.3e-06 26.7 0.0 6.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ03792.1 - 1.3e-05 25.1 0.1 4.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ03792.1 - 1.8e-05 24.5 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ03792.1 - 3.1e-05 24.4 0.0 7.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ03792.1 - 0.0002 21.6 0.0 0.0006 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ03792.1 - 0.00021 20.6 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 OAJ03792.1 - 0.00035 20.9 0.0 0.00096 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain SDA1 PF05285.7 OAJ03792.1 - 0.0085 15.4 7.0 0.014 14.6 4.8 1.4 1 0 0 1 1 1 1 SDA1 Methyltransf_12 PF08242.7 OAJ03792.1 - 0.027 14.9 0.6 0.066 13.6 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ03792.1 - 0.03 15.1 0.1 0.16 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 OAJ03792.1 - 0.045 12.4 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.10 OAJ03792.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Granulin PF00396.13 OAJ03793.1 - 2.6 8.2 43.3 1.3 9.1 2.4 3.7 1 1 2 3 3 3 0 Granulin Nt_Gln_amidase PF09764.4 OAJ03794.1 - 5e-26 91.1 0.0 1.5e-07 30.8 0.0 4.9 4 1 0 4 4 4 4 N-terminal glutamine amidase GRASP55_65 PF04495.9 OAJ03795.1 - 6e-61 204.4 0.0 2.4e-49 166.8 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Abhydrolase_5 PF12695.2 OAJ03797.1 - 0.00015 21.5 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ03797.1 - 0.032 13.4 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family zf-RING_2 PF13639.1 OAJ03802.1 - 8.3e-07 28.7 1.8 8.6e-05 22.2 0.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ03802.1 - 1.6e-05 24.4 3.4 4.1e-05 23.1 0.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ03802.1 - 0.011 15.3 2.8 0.051 13.3 0.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 OAJ03802.1 - 0.012 15.6 1.6 0.012 15.6 1.1 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 OAJ03802.1 - 0.097 12.3 12.4 0.052 13.2 0.4 3.0 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_4 PF15227.1 OAJ03802.1 - 0.17 11.7 5.4 0.036 13.9 0.9 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ03802.1 - 0.21 11.2 8.4 0.13 11.9 0.3 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 OAJ03802.1 - 0.23 11.5 10.6 0.1 12.6 3.0 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type FHA PF00498.21 OAJ03803.1 - 0.042 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 FHA domain MULE PF10551.4 OAJ03804.1 - 2.6e-15 56.3 0.0 4.7e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ03804.1 - 1.1e-09 37.3 0.0 1.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Pox_G7 PF05503.7 OAJ03804.1 - 0.03 12.9 0.0 0.044 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like Peptidase_S30 PF01577.11 OAJ03805.1 - 0.22 10.8 5.7 0.25 10.7 4.0 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease Pol_alpha_B_N PF08418.5 OAJ03805.1 - 0.24 10.8 4.1 0.32 10.5 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SR-25 PF10500.4 OAJ03805.1 - 0.56 9.6 12.0 0.7 9.3 8.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_tranf_2_3 PF13641.1 OAJ03806.1 - 9e-18 64.8 0.3 6.2e-16 58.8 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ03806.1 - 8.8e-13 48.3 6.9 8.8e-13 48.3 4.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ03806.1 - 9.4e-12 44.0 6.1 9.3e-10 37.5 4.1 3.2 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.1 OAJ03806.1 - 5.1e-11 42.1 0.1 1.1e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ03806.1 - 7.8e-05 22.4 0.1 0.026 14.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF1049 PF06305.6 OAJ03806.1 - 0.33 10.4 4.1 0.12 11.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Glyco_hydro_16 PF00722.16 OAJ03807.1 - 4e-17 62.1 0.2 6.3e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sad1_UNC PF07738.8 OAJ03808.1 - 1.7e-11 44.0 0.0 9.7e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1664 PF07889.7 OAJ03808.1 - 0.25 11.1 0.3 0.5 10.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ETF PF01012.16 OAJ03809.1 - 4.2e-35 120.8 3.2 6e-35 120.3 2.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain BOP1NT PF08145.7 OAJ03810.1 - 5.2e-103 344.3 1.3 7.3e-103 343.8 0.9 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 OAJ03810.1 - 1.2e-25 88.4 0.2 2.5e-05 23.9 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF2457 PF10446.4 OAJ03810.1 - 0.018 13.7 27.5 0.032 12.9 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.5 OAJ03810.1 - 2.7 6.9 22.0 4.5 6.2 15.2 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 OAJ03810.1 - 5 5.4 24.4 9.3 4.5 16.9 1.3 1 0 0 1 1 1 0 Daxx Family Maf1 PF09174.5 OAJ03812.1 - 6.7e-25 87.9 6.0 6e-16 58.8 0.0 3.9 4 0 0 4 4 4 3 Maf1 regulator Atg14 PF10186.4 OAJ03814.1 - 1.7e-05 23.9 8.8 1.8e-05 23.8 6.1 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 OAJ03814.1 - 5.9e-05 22.6 8.8 7.2e-05 22.3 6.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 OAJ03814.1 - 6.1e-05 21.6 7.1 6.5e-05 21.5 4.9 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain FH2 PF02181.18 OAJ03814.1 - 0.0007 18.5 3.5 0.00088 18.2 2.4 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Allexi_40kDa PF05549.6 OAJ03814.1 - 0.00074 18.9 0.8 0.00084 18.7 0.6 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein Tho2 PF11262.3 OAJ03814.1 - 0.0008 18.5 3.3 0.00096 18.2 2.3 1.1 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 IncA PF04156.9 OAJ03814.1 - 0.00083 18.9 14.5 0.0012 18.5 10.1 1.2 1 0 0 1 1 1 1 IncA protein TMF_DNA_bd PF12329.3 OAJ03814.1 - 0.0013 18.5 17.1 0.0029 17.3 10.9 1.9 1 1 1 2 2 2 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 OAJ03814.1 - 0.0018 16.8 9.8 0.0022 16.5 6.8 1.0 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.15 OAJ03814.1 - 0.0023 17.6 16.4 0.035 13.8 4.5 2.1 1 1 1 2 2 2 2 Prefoldin subunit DMPK_coil PF08826.5 OAJ03814.1 - 0.0026 17.5 19.5 0.0031 17.3 8.5 2.8 1 1 1 2 2 2 2 DMPK coiled coil domain like DUF940 PF06082.6 OAJ03814.1 - 0.0045 15.6 3.5 0.0048 15.5 2.5 1.0 1 0 0 1 1 1 1 Bacterial putative lipoprotein (DUF940) MADF_DNA_bdg PF10545.4 OAJ03814.1 - 0.008 16.3 2.3 0.012 15.8 1.6 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like BBP1_C PF15272.1 OAJ03814.1 - 0.011 15.3 8.9 0.013 15.0 6.2 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Tropomyosin_1 PF12718.2 OAJ03814.1 - 0.017 14.9 18.2 0.2 11.4 12.6 2.0 1 1 0 1 1 1 0 Tropomyosin like CHDCT2 PF08074.6 OAJ03814.1 - 0.017 14.8 2.1 0.022 14.4 1.4 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF812 PF05667.6 OAJ03814.1 - 0.02 13.4 9.9 0.024 13.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF342 PF03961.8 OAJ03814.1 - 0.021 13.2 7.8 0.025 13.0 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 OAJ03814.1 - 0.023 12.5 6.1 0.024 12.4 4.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 OAJ03814.1 - 0.024 13.4 7.7 0.029 13.1 5.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DivIC PF04977.10 OAJ03814.1 - 0.024 14.1 16.9 0.22 11.0 4.6 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF3584 PF12128.3 OAJ03814.1 - 0.025 11.9 9.8 0.028 11.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) L_lactis_ph-MCP PF06673.6 OAJ03814.1 - 0.025 13.3 4.2 0.038 12.7 2.9 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Fez1 PF06818.10 OAJ03814.1 - 0.03 14.3 10.6 0.035 14.1 7.4 1.1 1 0 0 1 1 1 0 Fez1 Ran-binding PF05508.6 OAJ03814.1 - 0.033 13.0 2.1 0.041 12.7 1.5 1.1 1 0 0 1 1 1 0 RanGTP-binding protein PspA_IM30 PF04012.7 OAJ03814.1 - 0.035 13.4 14.9 0.16 11.3 1.3 2.0 1 1 1 2 2 2 0 PspA/IM30 family Ndc1_Nup PF09531.5 OAJ03814.1 - 0.043 12.2 0.9 0.043 12.2 0.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCN5L1 PF06320.8 OAJ03814.1 - 0.043 13.6 5.2 0.059 13.2 3.6 1.2 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF3540 PF12059.3 OAJ03814.1 - 0.044 13.4 1.5 0.052 13.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) FlxA PF14282.1 OAJ03814.1 - 0.044 13.7 14.7 0.11 12.4 2.6 2.0 1 1 1 2 2 2 0 FlxA-like protein Med9 PF07544.8 OAJ03814.1 - 0.065 12.9 9.9 0.12 12.1 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3450 PF11932.3 OAJ03814.1 - 0.065 12.4 7.0 0.094 11.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ISG65-75 PF11727.3 OAJ03814.1 - 0.07 12.1 5.8 0.079 12.0 4.0 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein DASH_Spc34 PF08657.5 OAJ03814.1 - 0.075 12.6 16.5 0.45 10.1 5.5 2.0 1 1 1 2 2 2 0 DASH complex subunit Spc34 THOC7 PF05615.8 OAJ03814.1 - 0.082 13.1 11.7 0.1 12.8 8.1 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 HlyD PF00529.15 OAJ03814.1 - 0.11 11.8 10.0 0.12 11.6 6.9 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Fib_alpha PF08702.5 OAJ03814.1 - 0.11 12.5 4.6 0.18 11.9 3.2 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AceK PF06315.6 OAJ03814.1 - 0.12 10.6 1.2 0.14 10.4 0.8 1.3 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) DUF1319 PF07028.6 OAJ03814.1 - 0.13 12.4 5.9 0.3 11.3 4.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) Sec20 PF03908.8 OAJ03814.1 - 0.14 11.8 1.7 0.23 11.2 0.4 1.8 1 1 1 2 2 2 0 Sec20 Casc1 PF12366.3 OAJ03814.1 - 0.15 11.5 4.0 0.17 11.3 2.8 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF2968 PF11180.3 OAJ03814.1 - 0.16 11.3 13.9 0.37 10.1 9.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF2450 PF10475.4 OAJ03814.1 - 0.18 10.6 2.3 0.21 10.4 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) GP41 PF00517.12 OAJ03814.1 - 0.19 11.2 1.6 0.3 10.6 0.7 1.5 1 1 0 1 1 1 0 Retroviral envelope protein ADIP PF11559.3 OAJ03814.1 - 0.2 11.5 13.1 1 9.2 8.8 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.3 OAJ03814.1 - 0.2 11.3 4.8 3 7.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Seryl_tRNA_N PF02403.17 OAJ03814.1 - 0.22 11.5 12.5 0.62 10.1 8.6 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 OAJ03814.1 - 0.22 11.4 17.0 0.17 11.8 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1515 PF07439.6 OAJ03814.1 - 0.24 11.2 4.9 0.32 10.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) SecD-TM1 PF13721.1 OAJ03814.1 - 0.26 11.5 2.3 0.31 11.3 1.0 1.5 1 1 0 1 1 1 0 SecD export protein N-terminal TM region BTV_NS2 PF04514.7 OAJ03814.1 - 0.3 9.9 8.0 0.34 9.7 5.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF445 PF04286.7 OAJ03814.1 - 0.34 10.4 6.1 0.38 10.2 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Spc7 PF08317.6 OAJ03814.1 - 0.34 9.5 14.0 0.91 8.1 9.8 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-C4H2 PF10146.4 OAJ03814.1 - 0.34 10.8 8.0 0.44 10.5 5.6 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein HSBP1 PF06825.7 OAJ03814.1 - 0.39 10.3 2.2 1.1 8.8 0.3 2.1 1 1 1 2 2 2 0 Heat shock factor binding protein 1 BLOC1_2 PF10046.4 OAJ03814.1 - 0.45 10.6 5.7 1.1 9.4 3.9 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.4 OAJ03814.1 - 0.46 10.2 18.3 0.78 9.5 7.1 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Mnd1 PF03962.10 OAJ03814.1 - 0.47 10.0 16.8 0.66 9.6 5.7 2.0 1 1 1 2 2 2 0 Mnd1 family Peptidase_S46 PF10459.4 OAJ03814.1 - 0.52 8.6 5.8 0.63 8.3 4.0 1.0 1 0 0 1 1 1 0 Peptidase S46 Herpes_UL25 PF01499.11 OAJ03814.1 - 0.6 8.3 9.8 0.73 8.0 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF641 PF04859.7 OAJ03814.1 - 0.64 9.7 11.7 4.9 6.9 0.5 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF603 PF04645.7 OAJ03814.1 - 0.64 9.9 7.4 3 7.7 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF603 FliD_C PF07195.7 OAJ03814.1 - 0.65 9.2 3.3 5 6.3 2.3 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FemAB PF02388.11 OAJ03814.1 - 0.67 8.5 6.0 0.83 8.2 4.1 1.2 1 0 0 1 1 1 0 FemAB family ATG16 PF08614.6 OAJ03814.1 - 0.71 9.6 15.7 16 5.2 11.1 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc24 PF08286.6 OAJ03814.1 - 0.72 9.5 14.2 2 8.1 2.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Viral_P18 PF04521.8 OAJ03814.1 - 0.75 9.2 9.9 0.41 10.1 1.0 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF4140 PF13600.1 OAJ03814.1 - 0.79 10.2 17.2 5.4 7.5 4.7 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4315 PF14193.1 OAJ03814.1 - 0.97 9.4 17.6 4.5 7.2 2.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4315) AKNA PF12443.3 OAJ03814.1 - 1 9.4 6.1 1.5 8.8 4.3 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor TMPIT PF07851.8 OAJ03814.1 - 1 8.3 3.7 1.2 8.1 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin PF00804.20 OAJ03814.1 - 1.1 9.4 9.9 1.5 8.9 6.9 1.3 1 0 0 1 1 1 0 Syntaxin Occludin_ELL PF07303.8 OAJ03814.1 - 1.1 10.0 7.2 5.6 7.7 1.4 2.1 1 1 1 2 2 2 0 Occludin homology domain HR1 PF02185.11 OAJ03814.1 - 1.1 8.9 13.3 13 5.5 8.8 2.5 1 1 1 2 2 2 0 Hr1 repeat DUF4618 PF15397.1 OAJ03814.1 - 1.2 8.4 10.4 2.6 7.3 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) M PF02370.11 OAJ03814.1 - 1.2 9.7 15.3 2.2 8.8 0.2 4.2 2 2 3 5 5 4 0 M protein repeat Prefoldin PF02996.12 OAJ03814.1 - 1.3 8.6 10.2 0.99 9.0 2.8 2.2 1 1 1 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.5 OAJ03814.1 - 1.3 9.0 16.6 4.7 7.3 11.5 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil Phlebovirus_NSM PF07246.6 OAJ03814.1 - 1.3 8.0 6.7 1.6 7.7 4.6 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4164 PF13747.1 OAJ03814.1 - 1.4 9.1 18.4 0.054 13.6 6.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) HXXSHH PF07586.6 OAJ03814.1 - 1.4 7.7 5.2 1.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) HSCB_C PF07743.8 OAJ03814.1 - 1.6 9.2 20.3 0.4 11.1 3.6 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Cep57_CLD_2 PF14197.1 OAJ03814.1 - 1.8 8.5 16.9 2.9 7.8 11.7 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 APG6 PF04111.7 OAJ03814.1 - 1.8 7.4 17.4 1.1 8.2 9.8 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF572 PF04502.8 OAJ03814.1 - 2.1 7.5 14.0 2.2 7.3 9.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) YlqD PF11068.3 OAJ03814.1 - 2.2 8.2 11.2 4.2 7.4 7.6 1.5 1 1 0 1 1 1 0 YlqD protein DUF947 PF06102.7 OAJ03814.1 - 2.4 7.9 9.9 3.4 7.4 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) FUSC PF04632.7 OAJ03814.1 - 2.4 6.4 5.3 2.6 6.3 3.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Phage_GP20 PF06810.6 OAJ03814.1 - 2.4 7.5 9.2 5.9 6.3 2.0 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4446 PF14584.1 OAJ03814.1 - 2.5 7.9 7.2 13 5.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Striatin PF08232.7 OAJ03814.1 - 2.6 8.3 13.9 3.4 7.9 9.7 1.2 1 0 0 1 1 1 0 Striatin family Sec2p PF06428.6 OAJ03814.1 - 2.6 7.9 12.0 9.9 6.0 8.3 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p Snapin_Pallidin PF14712.1 OAJ03814.1 - 2.6 8.4 7.5 3.2 8.1 0.7 2.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF724 PF05266.9 OAJ03814.1 - 2.7 7.5 14.2 1.3 8.5 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GBP_C PF02841.9 OAJ03814.1 - 2.7 7.1 12.6 2.9 6.9 8.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Snf7 PF03357.16 OAJ03814.1 - 2.7 7.3 14.1 3.9 6.8 1.2 2.1 1 1 1 2 2 2 0 Snf7 CASP_C PF08172.7 OAJ03814.1 - 2.9 6.8 11.8 1.9 7.4 3.6 2.0 1 1 1 2 2 2 0 CASP C terminal GrpE PF01025.14 OAJ03814.1 - 3.2 7.2 17.6 1.3e+02 2.0 12.2 2.1 1 1 0 1 1 1 0 GrpE DUF972 PF06156.8 OAJ03814.1 - 3.7 7.9 10.2 8.7 6.7 7.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) CENP-H PF05837.7 OAJ03814.1 - 4.5 7.5 12.8 5.3 7.2 8.0 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Dzip-like_N PF13815.1 OAJ03814.1 - 4.6 7.0 11.1 1.1 9.1 3.7 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF465 PF04325.8 OAJ03814.1 - 4.9 6.9 11.6 0.35 10.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Paralemmin PF03285.10 OAJ03814.1 - 5.9 6.2 13.4 0.88 8.9 5.6 1.9 2 0 0 2 2 2 0 Paralemmin Swi5 PF07061.6 OAJ03814.1 - 6.2 6.6 9.2 16 5.3 2.2 2.2 1 1 1 2 2 2 0 Swi5 DUF2203 PF09969.4 OAJ03814.1 - 6.3 7.0 9.2 5.1 7.3 2.2 1.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MCC-bdg_PDZ PF10506.4 OAJ03814.1 - 6.8 6.6 10.6 1 9.2 1.1 2.2 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome AAA_23 PF13476.1 OAJ03814.1 - 7.2 6.8 12.8 8.6 6.6 8.9 1.2 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 OAJ03814.1 - 8.8 4.4 14.4 0.33 9.1 3.2 1.9 1 1 1 2 2 2 0 Transmembrane protein MerR-DNA-bind PF09278.6 OAJ03814.1 - 9.4 6.7 16.3 17 5.8 3.3 2.6 1 1 1 2 2 2 0 MerR, DNA binding DUF676 PF05057.9 OAJ03815.1 - 8.2e-32 110.2 0.0 8.3e-25 87.3 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ03815.1 - 0.056 13.1 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ03815.1 - 0.058 13.2 2.3 0.69 9.7 1.6 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Alpha-amylase PF00128.19 OAJ03816.1 - 3.6e-82 276.2 0.0 4.9e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 OAJ03816.1 - 0.038 12.8 0.1 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme F-box PF00646.28 OAJ03817.1 - 1.8e-05 24.2 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF676 PF05057.9 OAJ03818.1 - 1.6e-29 102.7 0.0 4.5e-21 75.1 0.0 2.4 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 OAJ03818.1 - 3.6e-06 26.8 0.0 2.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ03818.1 - 4.4e-06 26.7 0.7 3.7e-05 23.7 0.0 2.4 1 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ03818.1 - 0.00085 18.9 0.2 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 OAJ03818.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 OAJ03819.1 - 2.7e-18 66.0 0.0 1.1e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ03819.1 - 2.6e-05 23.4 0.1 0.00086 18.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 OAJ03819.1 - 0.0081 15.9 0.6 0.022 14.5 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 OAJ03820.1 - 0.28 10.4 2.0 0.38 10.0 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2838 PF10998.3 OAJ03821.1 - 1.7e-37 127.7 8.7 4.2e-37 126.4 6.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Cellulase PF00150.13 OAJ03822.1 - 7e-11 41.8 7.0 1.1e-10 41.1 4.8 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Corona_nucleoca PF00937.13 OAJ03822.1 - 0.34 9.8 10.3 0.54 9.1 7.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Golgin_A5 PF09787.4 OAJ03822.1 - 1 7.8 9.2 1.4 7.3 6.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 SOBP PF15279.1 OAJ03822.1 - 1.8 8.9 4.1 5.8 7.2 2.7 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein Ribosomal_L15e PF00827.12 OAJ03823.1 - 1.9e-87 291.7 8.0 2.3e-87 291.4 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L18p PF00861.17 OAJ03824.1 - 2e-39 134.4 1.4 3.3e-39 133.7 0.0 2.0 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 OAJ03824.1 - 1.2e-34 118.6 4.7 2.9e-34 117.5 3.3 1.6 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region MtrA PF04208.9 OAJ03824.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A BCNT PF07572.7 OAJ03825.1 - 2e-14 53.2 6.7 2.5e-13 49.7 4.6 2.2 1 1 0 1 1 1 1 Bucentaur or craniofacial development PBP_sp32 PF07222.7 OAJ03825.1 - 0.11 11.6 1.6 0.17 10.9 1.1 1.4 1 1 0 1 1 1 0 Proacrosin binding protein sp32 NRDE PF05742.7 OAJ03826.1 - 1.3e-35 123.0 0.0 1.1e-30 106.9 0.0 2.8 2 1 0 2 2 2 2 NRDE protein Alg6_Alg8 PF03155.10 OAJ03827.1 - 5.4e-117 391.5 20.8 5.2e-82 276.1 7.2 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family PGM_PMM_I PF02878.11 OAJ03828.1 - 8.6e-21 73.8 0.1 7.1e-11 41.7 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 OAJ03828.1 - 3.7e-11 43.2 0.0 1.7e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 OAJ03828.1 - 8.4e-10 38.5 0.1 2.4e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 OAJ03828.1 - 3.6e-05 23.7 0.0 7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF4210 PF13915.1 OAJ03829.1 - 1.4e-18 66.8 0.0 3.8e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 OAJ03829.1 - 5.8e-13 48.5 0.0 1.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis Aldose_epim PF01263.15 OAJ03830.1 - 7.2e-30 104.1 0.1 8.9e-30 103.8 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase SNF2_N PF00176.18 OAJ03831.1 - 1.2e-68 231.1 0.0 3.4e-67 226.3 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ03831.1 - 4.9e-16 58.3 0.1 1.3e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ03831.1 - 2.1e-08 33.3 1.4 6e-07 28.5 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ03831.1 - 6.5e-07 29.3 0.0 7.3e-06 25.9 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Rifin_STEVOR PF02009.11 OAJ03832.1 - 0.36 10.4 1.4 0.92 9.0 1.0 1.6 1 0 0 1 1 1 0 Rifin/stevor family Actin PF00022.14 OAJ03833.1 - 3.2e-105 351.7 0.0 4.3e-105 351.3 0.0 1.2 1 0 0 1 1 1 1 Actin STE PF02200.11 OAJ03837.1 - 3.4e-35 120.5 0.0 6e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor WD40 PF00400.27 OAJ03838.1 - 1.3e-33 113.6 13.1 4.9e-07 29.3 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat dCMP_cyt_deam_1 PF00383.17 OAJ03839.1 - 4.1e-21 74.5 0.0 5.8e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 OAJ03839.1 - 5.7e-07 29.4 0.0 8.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase DUF3759 PF12585.3 OAJ03840.1 - 0.0011 18.8 0.3 0.0014 18.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) zf-SNAP50_C PF12251.3 OAJ03841.1 - 1.1e-10 41.1 0.0 2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Drf_FH1 PF06346.7 OAJ03842.1 - 0.00013 21.5 28.6 0.00013 21.5 19.8 4.7 2 1 2 4 4 4 1 Formin Homology Region 1 Sdh5 PF03937.11 OAJ03843.1 - 4.7e-22 77.4 0.4 2.2e-21 75.2 0.1 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Pterin_4a PF01329.14 OAJ03844.1 - 9.2e-27 92.6 0.2 1.3e-26 92.1 0.1 1.3 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sld5 PF05916.6 OAJ03845.1 - 5e-05 23.5 0.1 8.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein PP2C PF00481.16 OAJ03848.1 - 3.1e-32 111.9 0.0 1.7e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Radical_SAM PF04055.16 OAJ03849.1 - 6e-16 59.0 0.4 4.2e-15 56.3 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 OAJ03849.1 - 1.4e-10 41.0 0.0 4.1e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 OAJ03849.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 OAJ03849.1 - 0.041 13.9 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Nol1_Nop2_Fmu PF01189.12 OAJ03850.1 - 1.1e-92 310.4 0.0 1.4e-92 310.0 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 OAJ03850.1 - 0.0002 21.3 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 OAJ03850.1 - 0.00025 20.6 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 OAJ03850.1 - 0.00053 19.6 0.0 0.00093 18.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 OAJ03850.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mannosyl_trans3 PF11051.3 OAJ03851.1 - 2.6e-13 49.9 0.0 1.1e-07 31.4 0.0 2.9 2 1 0 2 2 2 2 Mannosyltransferase putative Gag_p30 PF02093.11 OAJ03851.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Gag P30 core shell protein XAP5 PF04921.9 OAJ03852.1 - 2.6e-95 318.5 8.7 2.6e-95 318.5 6.0 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator TSKS PF15358.1 OAJ03854.1 - 0.21 9.6 1.4 0.3 9.1 1.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate DUF1604 PF07713.8 OAJ03855.1 - 1.8e-32 110.9 12.3 2.6e-28 97.6 3.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1604) G-patch PF01585.18 OAJ03855.1 - 3.8e-05 23.3 0.6 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 OAJ03855.1 - 0.0012 18.5 0.5 0.0086 15.9 0.1 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site GPI-anchored PF10342.4 OAJ03856.1 - 7.5e-07 29.5 0.0 2.4e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SMC_Nse1 PF07574.8 OAJ03857.1 - 5.4e-19 68.6 2.5 4.7e-10 39.4 0.0 2.5 2 1 1 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex Myc_N PF01056.13 OAJ03857.1 - 0.00016 20.9 8.5 0.00025 20.3 5.9 1.4 1 0 0 1 1 1 1 Myc amino-terminal region zf-RING-like PF08746.6 OAJ03857.1 - 0.0023 17.8 5.8 0.0044 16.9 4.0 1.5 1 0 0 1 1 1 1 RING-like domain BSP_II PF05432.6 OAJ03857.1 - 0.0039 16.5 11.5 0.0052 16.0 8.0 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleo_P87 PF07267.6 OAJ03857.1 - 0.026 13.2 1.3 0.032 12.9 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FCP1_C PF09309.5 OAJ03857.1 - 0.063 12.5 14.9 0.1 11.9 10.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Baculo_RING PF05883.6 OAJ03857.1 - 0.11 12.2 0.5 0.22 11.3 0.3 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_2 PF13639.1 OAJ03857.1 - 0.4 10.5 5.9 0.67 9.8 4.1 1.4 1 0 0 1 1 1 0 Ring finger domain Spore_coat_CotO PF14153.1 OAJ03857.1 - 2.8 7.3 10.4 4.3 6.7 7.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FLO_LFY PF01698.11 OAJ03857.1 - 4.2 6.1 8.2 6.3 5.5 5.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FANCL_C PF11793.3 OAJ03857.1 - 4.8 7.2 6.0 20 5.2 3.8 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain ORC6 PF05460.8 OAJ03857.1 - 4.9 6.1 11.6 7 5.6 8.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DDHD PF02862.12 OAJ03857.1 - 5.9 6.6 9.1 11 5.6 6.3 1.4 1 0 0 1 1 1 0 DDHD domain PBP1_TM PF14812.1 OAJ03857.1 - 7.3 6.9 25.9 0.34 11.2 10.9 2.9 1 1 2 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0086 PF01868.11 OAJ03858.1 - 1.1e-11 44.1 0.0 3.2e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function UPF0086 PilJ PF13675.1 OAJ03858.1 - 0.016 15.4 6.9 0.033 14.5 1.3 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Cyclin PF08613.6 OAJ03859.1 - 2.8e-10 40.7 0.0 6.5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin GIY-YIG PF01541.19 OAJ03860.1 - 2.3e-05 24.6 0.0 9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 GIY-YIG catalytic domain Neugrin PF06413.6 OAJ03860.1 - 4.4 7.0 12.1 0.29 10.9 2.7 2.3 2 0 0 2 2 2 0 Neugrin 4HBT_3 PF13622.1 OAJ03861.1 - 3.6e-28 99.0 2.1 4.7e-28 98.6 1.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ03861.1 - 1.6e-06 27.7 0.0 5.8e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase 4HBT PF03061.17 OAJ03861.1 - 0.00038 20.5 0.1 0.027 14.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily Fib_alpha PF08702.5 OAJ03862.1 - 0.63 10.1 16.0 0.1 12.7 2.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 OAJ03862.1 - 4.5 7.0 11.3 5 6.9 4.3 3.4 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Pox_A_type_inc PF04508.7 OAJ03862.1 - 7.5 6.6 11.1 1.1 9.2 0.2 4.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.15 OAJ03862.1 - 9.5 5.2 23.5 0.02 13.9 2.8 3.1 1 1 0 2 2 2 0 Tropomyosin Dimer_Tnp_hAT PF05699.9 OAJ03863.1 - 0.0001 21.8 0.0 0.0007 19.1 0.0 2.3 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Abhydrolase_1 PF00561.15 OAJ03870.1 - 2.3e-15 56.7 0.1 1.2e-13 51.1 0.1 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 OAJ03870.1 - 1.2e-11 44.3 0.0 2.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 OAJ03870.1 - 1.3e-10 41.6 0.3 1.5e-09 38.0 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ03870.1 - 0.005 16.6 0.0 0.034 13.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family CLTH PF10607.4 OAJ03877.1 - 1.2e-18 67.2 0.0 2.4e-18 66.2 0.0 1.5 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 OAJ03877.1 - 0.027 14.2 0.2 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 LisH UQ_con PF00179.21 OAJ03878.1 - 2.1e-20 72.6 0.0 3.5e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ03878.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 RWD domain CHORD PF04968.7 OAJ03880.1 - 1e-41 140.9 17.7 1.1e-22 80.0 3.4 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 OAJ03880.1 - 3.1e-09 37.2 0.0 4.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 CS domain Ribosomal_S6 PF01250.12 OAJ03881.1 - 4.8e-14 51.9 0.0 5.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 FA_hydroxylase PF04116.8 OAJ03882.1 - 9.2e-16 58.2 16.0 2.1e-15 57.1 11.1 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF2013 PF09431.5 OAJ03883.1 - 2.9e-50 169.6 1.3 6e-50 168.6 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF3739 PF12545.3 OAJ03883.1 - 0.14 12.3 4.6 0.31 11.1 3.2 1.5 1 0 0 1 1 1 0 Filamentous haemagglutinin family outer membrane protein RRM_1 PF00076.17 OAJ03884.1 - 3.5e-35 119.4 0.0 6.1e-20 70.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ03884.1 - 6.8e-31 106.0 0.0 1e-14 54.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03884.1 - 5e-22 77.4 0.0 4e-08 32.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 OAJ03884.1 - 1.7e-13 50.6 0.1 3.7e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 OAJ03884.1 - 0.00019 21.2 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ03884.1 - 0.0012 18.5 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lipase_GDSL_2 PF13472.1 OAJ03885.1 - 1.5e-24 87.0 0.0 1.9e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ03885.1 - 8e-23 81.4 0.0 1e-22 81.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TEA PF01285.13 OAJ03886.1 - 2.3e-31 109.4 0.0 8.2e-31 107.6 0.0 2.0 1 1 0 1 1 1 1 TEA/ATTS domain family Integrin_b_cyt PF08725.6 OAJ03886.1 - 0.14 11.5 0.3 0.3 10.5 0.2 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Arm PF00514.18 OAJ03887.1 - 5.8e-69 225.7 29.5 6.2e-13 48.0 0.1 11.9 10 2 3 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ03887.1 - 3e-25 88.3 10.4 3.9e-06 27.0 0.1 7.1 2 1 2 5 5 5 5 HEAT repeats HEAT PF02985.17 OAJ03887.1 - 1.8e-19 67.9 11.7 0.074 13.1 0.0 9.1 8 0 0 8 8 8 6 HEAT repeat HEAT_EZ PF13513.1 OAJ03887.1 - 3e-17 62.5 6.0 0.013 15.9 0.0 8.4 6 2 2 8 8 8 5 HEAT-like repeat Adaptin_N PF01602.15 OAJ03887.1 - 6.8e-11 41.1 11.2 1.7e-08 33.2 0.6 2.4 2 1 0 3 3 3 2 Adaptin N terminal region KAP PF05804.7 OAJ03887.1 - 4.3e-10 38.1 2.3 7.4e-10 37.3 1.6 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 OAJ03887.1 - 1.9e-09 37.0 10.2 0.021 13.9 0.4 3.9 1 1 2 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 OAJ03887.1 - 8.3e-08 31.6 9.5 0.00044 19.4 3.0 4.4 1 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ03887.1 - 0.0006 19.7 4.3 6.1 6.7 0.0 4.6 2 1 3 5 5 5 2 V-ATPase subunit H DUF3361 PF11841.3 OAJ03887.1 - 0.0077 15.9 5.3 0.95 9.1 0.1 3.8 2 1 0 3 3 3 1 Domain of unknown function (DUF3361) HEAT_PBS PF03130.11 OAJ03887.1 - 0.016 15.6 10.0 93 3.9 0.0 7.6 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ03887.1 - 0.028 14.8 0.1 4.9 7.6 0.0 3.4 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region Tom37 PF10568.4 OAJ03887.1 - 0.066 13.4 2.8 3.3 8.0 0.0 4.0 5 0 0 5 5 5 0 Outer mitochondrial membrane transport complex protein YqfD PF06898.6 OAJ03887.1 - 0.13 10.9 0.0 0.26 9.9 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Dabb PF07876.7 OAJ03888.1 - 1.5e-21 76.6 0.1 1.8e-21 76.3 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Luteo_coat PF00894.13 OAJ03888.1 - 0.053 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Luteovirus coat protein Thr_synth_N PF14821.1 OAJ03889.1 - 1.1e-27 95.9 0.0 4.3e-27 93.9 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 OAJ03889.1 - 2.8e-20 72.7 0.1 4.4e-19 68.8 0.1 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Clat_adaptor_s PF01217.15 OAJ03890.1 - 7.5e-44 148.9 0.4 6.2e-34 116.7 0.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Chorismate_bind PF00425.13 OAJ03891.1 - 3.6e-72 242.7 0.0 6.9e-72 241.8 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 OAJ03891.1 - 1.2e-27 96.5 0.0 4.2e-18 65.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 OAJ03891.1 - 6.4e-15 55.3 0.0 9.9e-14 51.5 0.0 2.8 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 OAJ03891.1 - 0.00045 19.7 0.0 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 HAD_2 PF13419.1 OAJ03891.1 - 0.0052 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 OAJ03892.1 - 3.9e-07 29.2 0.2 7.8e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ03892.1 - 0.00062 19.6 14.8 0.001 18.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 OAJ03894.1 - 9.9e-39 129.8 9.4 6.7e-09 35.3 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ03894.1 - 3.7e-30 103.6 0.1 7.7e-30 102.6 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 OAJ03894.1 - 0.00011 21.6 0.2 0.22 11.0 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Rad51 PF08423.6 OAJ03895.1 - 2.5e-138 459.1 0.1 3e-138 458.8 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAJ03895.1 - 1.9e-14 53.5 0.0 2.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 OAJ03895.1 - 1.1e-08 34.4 0.1 1.6e-08 34.0 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 OAJ03895.1 - 2.5e-08 33.9 0.0 5.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 OAJ03895.1 - 1.3e-07 30.9 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KaiC PAXNEB PF05625.6 OAJ03895.1 - 0.0091 14.8 0.1 0.018 13.8 0.0 1.5 2 0 0 2 2 2 1 PAXNEB protein HHH PF00633.18 OAJ03895.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.10 OAJ03895.1 - 0.047 12.5 0.1 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ribosomal_S7e PF01251.13 OAJ03896.1 - 3.7e-79 264.6 0.1 4.1e-79 264.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e AAA_24 PF13479.1 OAJ03896.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain His_Phos_1 PF00300.17 OAJ03899.1 - 0.01 15.9 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 OAJ03900.1 - 4.6e-10 38.9 6.6 1.2e-05 24.9 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 OAJ03900.1 - 0.00017 21.3 0.0 0.44 10.2 0.0 4.0 5 0 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 OAJ03900.1 - 0.17 9.6 0.0 11 3.6 0.0 2.3 2 0 0 2 2 2 0 IKI3 family PD40 PF07676.7 OAJ03900.1 - 0.39 10.4 2.9 2.3 7.9 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.27 OAJ03901.1 - 9e-18 63.4 28.6 6.5e-07 29.0 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 OAJ03901.1 - 9.3e-15 54.4 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ribosomal_S8e PF01201.17 OAJ03901.1 - 0.11 12.6 0.3 0.19 11.8 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein S8e DUF4632 PF15451.1 OAJ03901.1 - 0.19 11.6 1.9 0.38 10.7 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) His_Phos_1 PF00300.17 OAJ03902.1 - 0.0034 17.4 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TraW_N PF12477.3 OAJ03902.1 - 4.9 7.2 5.6 10 6.1 3.9 1.6 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal E1-E2_ATPase PF00122.15 OAJ03903.1 - 1.4e-21 76.6 2.0 1.5e-21 76.4 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ03903.1 - 1.5e-17 64.7 0.0 1.3e-16 61.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ03903.1 - 1.7e-11 44.6 0.1 5e-11 43.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ03903.1 - 2.1e-06 27.6 0.0 6.4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ03903.1 - 0.00097 18.7 0.1 0.0026 17.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PSK_trans_fac PF07704.6 OAJ03903.1 - 0.53 11.0 2.9 16 6.2 0.6 2.7 1 1 1 2 2 2 0 Rv0623-like transcription factor TBCC PF07986.7 OAJ03904.1 - 2e-16 59.4 1.4 1.4e-15 56.7 0.9 2.0 2 0 0 2 2 2 1 Tubulin binding cofactor C UcrQ PF02939.11 OAJ03905.1 - 5.8e-19 67.6 3.7 7.1e-19 67.4 2.6 1.1 1 0 0 1 1 1 1 UcrQ family Acetyltransf_1 PF00583.19 OAJ03906.1 - 1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ03906.1 - 1.4e-11 44.4 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ03906.1 - 1.6e-06 28.3 0.0 2.3e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ03906.1 - 2.1e-05 24.6 0.0 2.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ03906.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 OAJ03906.1 - 0.0026 17.6 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PIP5K PF01504.13 OAJ03907.1 - 8.6e-83 277.3 0.0 1.6e-82 276.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Prenyltrans PF00432.16 OAJ03907.1 - 6e-44 147.2 2.5 2.2e-10 39.9 0.0 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ03907.1 - 1.3e-19 70.6 0.0 7.8e-10 39.1 0.0 4.0 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ03907.1 - 0.00019 21.4 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 Prenyltransferase-like RRM_1 PF00076.17 OAJ03908.1 - 4.7e-09 35.7 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ03908.1 - 2.3e-08 33.7 0.0 5.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 OAJ03908.1 - 0.00023 20.7 1.9 0.00036 20.1 1.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 OAJ03908.1 - 0.00036 20.4 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ03908.1 - 0.0021 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF515 PF04415.7 OAJ03910.1 - 0.5 8.5 11.8 0.68 8.1 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med3 PF11593.3 OAJ03910.1 - 1.1 8.4 24.5 1.5 7.9 17.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GMP_synt_C PF00958.17 OAJ03911.1 - 5.7e-41 138.1 0.0 1.1e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 OAJ03911.1 - 9.3e-37 126.3 0.0 1.5e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 OAJ03911.1 - 9.6e-11 41.0 0.1 1.7e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 OAJ03911.1 - 1e-09 38.1 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 OAJ03911.1 - 0.00069 18.2 0.2 0.0012 17.5 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 OAJ03911.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ03911.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 OAJ03911.1 - 0.0097 15.2 0.0 0.15 11.3 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.15 OAJ03911.1 - 0.022 14.2 0.2 0.053 13.0 0.0 1.7 2 0 0 2 2 2 0 PP-loop family DUF2392 PF10288.4 OAJ03911.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Arginosuc_synth PF00764.14 OAJ03911.1 - 0.084 11.9 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase Pil1 PF13805.1 OAJ03912.1 - 1.8e-26 92.9 0.0 3.4e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 IncA PF04156.9 OAJ03912.1 - 0.085 12.4 2.0 0.17 11.4 1.4 1.4 1 0 0 1 1 1 0 IncA protein Snapin_Pallidin PF14712.1 OAJ03912.1 - 0.11 12.8 0.4 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 Snapin/Pallidin GAS PF13851.1 OAJ03912.1 - 0.2 10.7 1.2 0.33 10.1 0.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GCR1_C PF12550.3 OAJ03915.1 - 0.00076 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_23 PF13384.1 OAJ03915.1 - 0.043 13.4 0.6 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 OAJ03915.1 - 0.052 13.5 1.6 0.58 10.1 0.2 2.9 3 0 0 3 3 3 0 Transposase FtsZ_C PF12327.3 OAJ03915.1 - 0.13 12.3 1.4 0.25 11.4 0.2 2.0 2 0 0 2 2 2 0 FtsZ family, C-terminal domain Pyridoxal_deC PF00282.14 OAJ03916.1 - 1.8e-62 210.9 0.0 2.7e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 OAJ03916.1 - 0.0062 15.3 0.0 0.0099 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V APH PF01636.18 OAJ03920.1 - 1.1e-36 126.7 0.0 1.9e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ03920.1 - 0.00039 19.6 0.0 0.00066 18.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 OAJ03920.1 - 0.00054 19.5 0.0 0.0008 19.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3673 PF12425.3 OAJ03920.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DUF1679 PF07914.6 OAJ03920.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Transposase_21 PF02992.9 OAJ03921.1 - 0.005 15.9 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DEAD PF00270.24 OAJ03922.1 - 6.9e-41 139.5 0.0 1.9e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ03922.1 - 4.5e-25 87.3 0.0 1.2e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 OAJ03922.1 - 1.5e-06 27.2 0.0 2.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ03922.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2986 PF11661.3 OAJ03922.1 - 0.002 18.3 1.0 0.002 18.3 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2986) CMS1 PF14617.1 OAJ03922.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit APH PF01636.18 OAJ03924.1 - 2.4e-37 128.9 0.0 4.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 OAJ03924.1 - 6.3e-06 25.5 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 OAJ03924.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 OAJ03924.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF3470 PF11953.3 OAJ03924.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3470) V_ATPase_I PF01496.14 OAJ03925.1 - 9.2e-273 906.6 0.0 1.1e-272 906.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 OAJ03925.1 - 0.012 15.3 0.6 0.041 13.6 0.4 1.7 2 0 0 2 2 2 0 Prefoldin subunit Cep57_MT_bd PF06657.8 OAJ03925.1 - 0.051 13.5 0.7 0.29 11.0 1.0 1.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 OAJ03925.1 - 0.079 12.6 0.6 0.15 11.7 0.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Med9 PF07544.8 OAJ03925.1 - 0.1 12.3 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 OAJ03925.1 - 0.3 11.4 1.4 5.6 7.4 0.5 2.9 3 0 0 3 3 3 0 SlyX IncA PF04156.9 OAJ03925.1 - 6.6 6.2 12.2 0.037 13.6 0.4 2.6 3 0 0 3 3 3 0 IncA protein JAB PF01398.16 OAJ03926.1 - 1.3e-15 57.1 0.0 2.5e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ03926.1 - 1.3e-07 31.1 0.2 3.2e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 OAJ03926.1 - 2.6e-05 24.1 0.0 5.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain PEP-utilisers_N PF05524.8 OAJ03926.1 - 0.0077 16.0 1.8 0.022 14.5 1.3 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal UIM PF02809.15 OAJ03926.1 - 0.025 14.1 2.9 0.059 12.9 2.0 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Thioredoxin PF00085.15 OAJ03927.1 - 7.8e-13 48.0 0.4 0.012 15.2 0.0 4.4 4 1 1 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 OAJ03927.1 - 5.5e-06 26.2 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain ECM11 PF15463.1 OAJ03927.1 - 0.031 14.5 0.7 0.031 14.5 0.5 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 NPV_P10 PF05531.7 OAJ03927.1 - 0.04 14.1 1.5 0.11 12.8 1.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Thioredoxin_8 PF13905.1 OAJ03927.1 - 0.046 13.8 0.2 1.8 8.7 0.0 3.3 4 0 0 4 4 4 0 Thioredoxin-like LON PF02190.11 OAJ03928.1 - 9.1e-12 45.0 0.0 7.6e-11 42.0 0.0 1.9 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain DUF3651 PF12371.3 OAJ03929.1 - 0.014 15.3 1.0 0.039 13.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3651) PARP PF00644.15 OAJ03930.1 - 2.3e-07 30.4 0.0 3.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PHF5 PF03660.9 OAJ03930.1 - 0.084 12.9 0.2 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 PHF5-like protein PHBC_N PF12551.3 OAJ03930.1 - 0.1 12.1 0.3 9.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal DUF1768 PF08719.6 OAJ03931.1 - 1.4e-30 106.1 0.0 1.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ03931.1 - 0.012 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 P34-Arc PF04045.9 OAJ03933.1 - 2.3e-106 354.5 0.1 3.2e-106 354.0 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF1768 PF08719.6 OAJ03934.1 - 4.8e-29 101.1 0.0 6.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.15 OAJ03935.1 - 8.6e-08 31.8 0.0 0.00018 20.9 0.0 2.0 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain CNH PF00780.17 OAJ03936.1 - 2.6e-36 125.4 0.0 4.9e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 OAJ03936.1 - 4.3e-24 85.3 1.1 6.6e-24 84.7 0.8 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ03936.1 - 4.9e-05 22.9 0.0 0.00014 21.4 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.1 OAJ03936.1 - 0.016 15.1 0.0 0.061 13.2 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain GST_N_3 PF13417.1 OAJ03938.1 - 5e-14 52.2 0.1 8.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ03938.1 - 6.8e-10 38.8 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ03938.1 - 1.4e-07 31.2 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ03938.1 - 3e-07 30.3 0.0 5.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ03938.1 - 5.9e-07 29.8 0.0 1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ03938.1 - 1.5e-05 25.0 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 OAJ03938.1 - 0.044 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Dfp1_Him1_M PF08630.5 OAJ03939.1 - 4.2e-30 104.0 0.0 7e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 OAJ03939.1 - 3.6e-21 74.5 1.6 6.6e-21 73.7 1.1 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 OAJ03939.1 - 0.0018 18.0 0.0 0.0058 16.4 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 OAJ03939.1 - 0.0026 17.8 0.0 0.0055 16.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-C2H2_2 PF12756.2 OAJ03939.1 - 0.052 13.6 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SSF PF00474.12 OAJ03940.1 - 1.5e-19 69.9 20.8 2.6e-19 69.1 14.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family S-AdoMet_synt_C PF02773.11 OAJ03941.1 - 1.2e-73 245.2 0.3 2.1e-73 244.5 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 OAJ03941.1 - 6.1e-49 164.9 0.0 1.1e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 OAJ03941.1 - 7.5e-44 148.0 0.1 1.5e-43 147.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain UCH PF00443.24 OAJ03942.1 - 1.5e-41 142.2 0.0 2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ03942.1 - 8e-14 51.7 0.0 2.3e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Adaptin_binding PF10199.4 OAJ03942.1 - 4.5 7.5 8.3 0.42 10.9 0.1 3.2 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 DNA_pol_A PF00476.15 OAJ03943.1 - 8.5e-90 301.1 0.0 2.2e-89 299.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family A SDA1 PF05285.7 OAJ03946.1 - 2 7.6 41.9 0.18 11.0 1.9 3.3 3 0 0 3 3 3 0 SDA1 Glyco_hydro_3 PF00933.16 OAJ03947.1 - 1.7e-84 283.3 0.0 2.8e-84 282.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ03947.1 - 9.9e-57 192.0 2.2 1.8e-55 187.9 0.4 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 OAJ03947.1 - 6.5e-19 67.6 0.0 1.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain XRN_N PF03159.13 OAJ03948.1 - 4e-97 324.2 0.0 7.9e-97 323.2 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PPR PF01535.15 OAJ03950.1 - 0.032 14.2 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 0 PPR repeat Cullin PF00888.17 OAJ03955.1 - 3.6e-22 78.6 0.0 2.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Cullin family GlutR_dimer PF00745.15 OAJ03955.1 - 0.0026 17.6 0.1 2.4 8.1 0.0 2.8 2 0 0 2 2 2 2 Glutamyl-tRNAGlu reductase, dimerisation domain FeoC PF09012.5 OAJ03955.1 - 0.039 13.6 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator Prenyltrans PF00432.16 OAJ03956.1 - 4.7e-29 99.6 12.2 1.7e-07 30.6 0.0 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 OAJ03956.1 - 4.5e-16 59.2 0.0 2.5e-14 53.6 0.0 2.7 2 0 0 2 2 2 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 OAJ03956.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 Prenyltransferase-like MRP-L46 PF11788.3 OAJ03957.1 - 5.8e-18 65.5 0.2 5.8e-18 65.5 0.1 2.6 3 1 0 3 3 3 1 39S mitochondrial ribosomal protein L46 AAA_32 PF13654.1 OAJ03957.1 - 0.023 13.3 0.1 0.1 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MOSC_N PF03476.11 OAJ03957.1 - 0.053 13.2 0.4 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain zf-H2C2_2 PF13465.1 OAJ03958.1 - 1.6e-08 34.4 7.7 5.9e-08 32.6 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ03958.1 - 0.00012 22.2 15.8 0.00038 20.6 0.6 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ03958.1 - 0.0019 18.4 1.0 0.0019 18.4 0.7 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ03958.1 - 0.2 11.5 2.0 2.5 8.1 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.7 OAJ03958.1 - 5 5.5 4.7 0.78 8.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Response_reg PF00072.19 OAJ03959.1 - 3.3e-06 27.0 0.0 0.00024 21.0 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Symplekin_C PF12295.3 OAJ03960.1 - 4.8e-52 176.5 0.1 1.6e-51 174.8 0.0 2.0 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 OAJ03960.1 - 3.3e-32 111.8 0.2 6.7e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_EZ PF13513.1 OAJ03960.1 - 0.0036 17.7 0.4 0.05 14.1 0.1 3.3 2 0 0 2 2 2 1 HEAT-like repeat DUF1746 PF08508.5 OAJ03961.1 - 4.9e-11 42.5 3.2 4.3e-10 39.5 2.2 2.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) ABC_tran PF00005.22 OAJ03962.1 - 6.3e-44 149.6 0.0 1.5e-21 77.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 OAJ03962.1 - 2.3e-23 81.8 1.5 2.3e-23 81.8 1.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ03962.1 - 2.4e-15 57.2 1.0 0.00018 21.5 0.0 4.4 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 OAJ03962.1 - 1.4e-12 47.3 0.1 1.3e-05 24.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 OAJ03962.1 - 1.4e-08 34.5 1.3 0.027 13.9 0.0 4.5 5 0 0 5 5 4 2 AAA-like domain AAA_22 PF13401.1 OAJ03962.1 - 1.4e-07 31.6 0.0 0.0061 16.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ03962.1 - 6.2e-07 28.8 0.1 0.0049 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ03962.1 - 7e-07 30.0 0.6 0.01 16.6 0.0 3.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 OAJ03962.1 - 3.8e-06 26.8 0.1 0.0063 16.4 0.0 2.8 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 OAJ03962.1 - 1.1e-05 25.9 0.0 0.25 11.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 OAJ03962.1 - 4e-05 23.3 0.1 0.071 12.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.12 OAJ03962.1 - 4.4e-05 23.4 2.1 0.0087 15.9 0.0 3.5 3 1 0 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 OAJ03962.1 - 4.5e-05 23.0 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ03962.1 - 0.00018 21.3 0.1 0.6 9.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 OAJ03962.1 - 0.00027 20.6 0.0 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ03962.1 - 0.00032 20.7 0.6 0.94 9.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 OAJ03962.1 - 0.00035 20.4 0.0 1.2 9.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 OAJ03962.1 - 0.00053 19.4 0.2 0.18 11.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 OAJ03962.1 - 0.00054 19.1 0.0 0.15 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ03962.1 - 0.00063 19.6 0.2 0.17 11.8 0.1 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 OAJ03962.1 - 0.00094 19.2 2.6 1.5 8.7 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.17 OAJ03962.1 - 0.0015 18.6 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 OAJ03962.1 - 0.0042 16.0 0.0 0.092 11.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ArgK PF03308.11 OAJ03962.1 - 0.0045 15.7 0.0 0.7 8.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_15 PF13175.1 OAJ03962.1 - 0.009 15.0 0.9 4 6.3 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.1 OAJ03962.1 - 0.016 15.5 9.6 0.14 12.4 0.0 3.7 3 1 0 4 4 4 0 AAA domain GTP_EFTU PF00009.22 OAJ03962.1 - 0.018 14.4 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 OAJ03962.1 - 0.018 15.3 0.3 1.9 8.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain MutS_V PF00488.16 OAJ03962.1 - 0.019 14.4 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Dynamin_N PF00350.18 OAJ03962.1 - 0.026 14.3 3.5 0.4 10.4 0.0 3.0 4 0 0 4 4 2 0 Dynamin family AAA PF00004.24 OAJ03962.1 - 0.11 12.6 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAJ03962.1 - 0.37 10.4 5.3 3.6 7.2 0.0 3.2 4 0 0 4 4 3 0 Archaeal ATPase 2OG-FeII_Oxy PF03171.15 OAJ03964.1 - 3.7e-20 72.0 0.0 6e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 OAJ03964.1 - 8.3e-20 71.4 0.0 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Carn_acyltransf PF00755.15 OAJ03965.1 - 2.8e-169 564.0 0.0 3.2e-169 563.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Med16 PF11635.3 OAJ03966.1 - 0.00032 18.8 0.0 0.0032 15.5 0.0 2.0 2 0 0 2 2 2 2 Mediator complex subunit 16 Ubiq_cyt_C_chap PF03981.7 OAJ03967.1 - 7.7e-30 103.6 0.1 5e-27 94.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone ACC_central PF08326.7 OAJ03968.1 - 4.3e-188 626.7 0.0 7.1e-188 626.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 OAJ03968.1 - 3.2e-161 537.0 0.0 4.1e-161 536.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 OAJ03968.1 - 4.8e-53 179.5 0.0 8.5e-53 178.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 OAJ03968.1 - 2.2e-24 85.6 0.1 5.2e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ03968.1 - 1.6e-21 76.2 0.0 3.1e-20 72.1 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 OAJ03968.1 - 1.5e-14 53.3 0.1 3.1e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 OAJ03968.1 - 2.8e-13 50.0 0.0 7.5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ03968.1 - 3.2e-08 32.7 0.0 1.2e-05 24.2 0.0 3.6 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 OAJ03968.1 - 3.7e-06 26.4 0.0 1.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 OAJ03968.1 - 0.0032 16.8 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 OAJ03968.1 - 0.0041 16.9 0.0 0.013 15.3 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain RnfC_N PF13375.1 OAJ03968.1 - 0.0061 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Dala_Dala_lig_C PF07478.8 OAJ03968.1 - 0.011 15.0 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RimK PF08443.6 OAJ03968.1 - 0.014 14.8 0.0 0.16 11.4 0.0 2.4 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD PF00529.15 OAJ03968.1 - 0.085 12.1 1.5 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_2 PF12700.2 OAJ03968.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein SEP PF08059.8 OAJ03969.1 - 2.1e-18 66.3 0.0 4.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 OAJ03969.1 - 6.1e-13 48.6 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 OAJ03969.1 - 2.4e-10 39.7 0.6 4.6e-10 38.8 0.4 1.5 1 0 0 1 1 1 1 UBA-like domain Mito_carr PF00153.22 OAJ03970.1 - 5.3e-29 99.7 4.5 5.7e-15 54.8 0.2 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein B12D PF06522.6 OAJ03971.1 - 4.5e-15 55.1 0.0 5.3e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Polysacc_deac_1 PF01522.16 OAJ03972.1 - 1.9e-27 95.3 0.0 3.8e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Aminotran_1_2 PF00155.16 OAJ03974.1 - 1.5e-41 142.6 0.0 2.6e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Gpi16 PF04113.9 OAJ03975.1 - 5e-92 308.7 0.0 9.6e-43 146.0 0.0 4.7 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component SYF2 PF08231.7 OAJ03976.1 - 2.7e-40 137.9 1.8 2.7e-40 137.9 1.3 2.3 2 0 0 2 2 2 1 SYF2 splicing factor WD40 PF00400.27 OAJ03976.1 - 0.12 12.2 4.9 12 6.0 0.0 4.5 5 1 0 5 5 5 0 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 OAJ03976.1 - 3.1 8.0 0.0 3.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DUF455 PF04305.9 OAJ03977.1 - 3e-93 311.7 0.0 3.9e-93 311.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 OAJ03977.1 - 1.7e-07 30.6 0.1 1.7e-07 30.6 0.1 2.7 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 OAJ03977.1 - 0.0015 18.2 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Amidase PF01425.16 OAJ03978.1 - 1.3e-91 307.6 0.0 2.1e-91 307.0 0.0 1.3 1 0 0 1 1 1 1 Amidase RabGAP-TBC PF00566.13 OAJ03979.1 - 2.8e-36 124.9 0.1 3.9e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ADSL_C PF10397.4 OAJ03979.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus OTCace_N PF02729.16 OAJ03980.1 - 4.5e-42 143.0 0.0 6.9e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 OAJ03980.1 - 2.1e-40 138.1 0.0 3.4e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Rft-1 PF04506.8 OAJ03983.1 - 2.7e-65 220.7 0.1 3.1e-64 217.3 0.1 2.4 2 1 0 2 2 2 1 Rft protein Pribosyltran_N PF13793.1 OAJ03984.1 - 3.8e-44 149.1 0.0 1.3e-42 144.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ03984.1 - 1.1e-33 116.5 1.3 9e-31 107.0 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ03984.1 - 6.6e-14 51.7 0.5 1.4e-12 47.4 0.4 2.8 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ03984.1 - 0.02 14.1 0.2 0.05 12.7 0.1 1.6 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase COQ7 PF03232.8 OAJ03985.1 - 1.1e-62 210.5 0.3 1.3e-62 210.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 OAJ03985.1 - 0.072 13.4 0.1 0.41 10.9 0.0 2.0 2 0 0 2 2 2 0 Rubrerythrin DUF3719 PF12516.3 OAJ03985.1 - 0.55 9.8 2.9 0.72 9.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF3446 PF11928.3 OAJ03985.1 - 5.1 7.3 16.3 0.15 12.2 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Bile_Hydr_Trans PF04775.9 OAJ03989.1 - 0.04 13.6 0.2 0.18 11.5 0.1 1.9 1 1 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region DUF3869 PF12985.2 OAJ03989.1 - 0.056 13.8 0.1 0.067 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3869) Thiolase_N PF00108.18 OAJ03989.1 - 0.08 11.9 0.0 0.08 11.9 0.0 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF1804 PF08822.6 OAJ03990.1 - 0.02 14.6 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) CBP4 PF07960.6 OAJ03991.1 - 2.4e-08 33.6 0.1 2.7e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 CBP4 HMG_CoA_synt_N PF01154.12 OAJ03992.1 - 5e-83 276.8 0.3 1.2e-82 275.6 0.2 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 OAJ03992.1 - 1.7e-82 277.1 0.0 2.3e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Ribosomal_L1 PF00687.16 OAJ03992.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family HSF_DNA-bind PF00447.12 OAJ03993.1 - 2.1e-34 117.7 0.7 3.3e-34 117.1 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HSP90 PF00183.13 OAJ03994.1 - 4.3e-247 820.7 23.0 5.4e-247 820.4 15.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 OAJ03994.1 - 1e-11 44.4 0.0 2.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ03994.1 - 4.4e-11 42.5 0.1 4.4e-11 42.5 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF45 PF01863.12 OAJ03994.1 - 0.66 9.7 12.1 2.7 7.7 3.7 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 F-box-like PF12937.2 OAJ03995.1 - 5.7e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.1 OAJ03997.1 - 1.3e-10 41.0 22.5 0.0026 17.6 0.0 7.8 6 2 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ03997.1 - 1.2e-09 37.2 7.4 0.054 13.4 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ03997.1 - 1.7e-07 30.5 0.3 3.4 7.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ03997.1 - 7.6e-07 28.6 11.3 0.088 12.4 0.2 6.2 6 0 0 6 6 6 3 TPR repeat TPR_14 PF13428.1 OAJ03997.1 - 0.00058 20.2 18.6 1.8 9.4 0.1 7.8 8 1 0 8 8 8 2 Tetratricopeptide repeat Apc5 PF12862.2 OAJ03997.1 - 0.016 15.0 0.0 1.8 8.4 0.0 4.0 5 1 0 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 OAJ03997.1 - 0.017 15.0 10.2 2.4 8.1 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ03997.1 - 0.022 14.5 0.0 13 5.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ03997.1 - 0.031 14.0 3.0 1.2 9.0 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat YIF1 PF03878.10 OAJ03998.1 - 1.9e-72 243.2 0.0 2.9e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 YIF1 Ribosomal_L11_N PF03946.9 OAJ03998.1 - 0.0074 15.7 1.4 0.0074 15.7 1.0 2.6 2 1 1 3 3 3 1 Ribosomal protein L11, N-terminal domain Yip1 PF04893.12 OAJ03998.1 - 0.15 11.5 15.2 0.019 14.4 5.5 2.3 1 1 1 2 2 2 0 Yip1 domain SUV3_C PF12513.3 OAJ03999.1 - 8.5e-15 53.9 0.3 1.7e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 OAJ03999.1 - 8.6e-11 41.5 0.0 2.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop14 PF04147.7 OAJ03999.1 - 0.63 7.8 9.5 0.97 7.2 6.6 1.2 1 0 0 1 1 1 0 Nop14-like family RNase_PH PF01138.16 OAJ04000.1 - 8.1e-34 116.7 0.1 1.1e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ04000.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HTH_31 PF13560.1 OAJ04000.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain MCM PF00493.18 OAJ04001.1 - 7.6e-133 442.3 0.0 1.2e-132 441.7 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 OAJ04001.1 - 5.4e-22 78.5 0.0 2.7e-21 76.2 0.0 2.2 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 OAJ04001.1 - 3.8e-08 33.1 0.0 1.1e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ04001.1 - 5.9e-07 28.8 0.0 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ04001.1 - 0.00018 21.1 0.0 0.0029 17.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ04001.1 - 0.0091 15.4 1.2 0.71 9.3 0.0 3.4 4 0 0 4 4 4 1 Sigma-54 interaction domain F-box-like PF12937.2 OAJ04002.1 - 2.7e-07 30.1 0.3 7.3e-07 28.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like SRF-TF PF00319.13 OAJ04003.1 - 8e-19 66.6 0.0 1.4e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_C54 PF03416.14 OAJ04004.1 - 8.4e-84 281.0 0.0 6.5e-83 278.0 0.0 2.2 1 1 0 1 1 1 1 Peptidase family C54 Sugar_tr PF00083.19 OAJ04005.1 - 7.8e-41 140.0 16.0 1.5e-40 139.1 11.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ04005.1 - 9.3e-25 87.0 24.7 3.3e-12 45.8 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2834 PF11196.3 OAJ04006.1 - 0.26 11.4 6.6 0.44 10.7 0.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) GHMP_kinases_N PF00288.21 OAJ04007.1 - 1.4e-07 31.4 2.3 2.6e-07 30.5 0.8 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain Hist_deacetyl PF00850.14 OAJ04007.1 - 0.15 11.2 0.0 9.9 5.3 0.0 2.1 2 0 0 2 2 2 0 Histone deacetylase domain CsbD PF05532.7 OAJ04008.1 - 2.7e-08 33.3 22.3 3.6e-05 23.3 4.3 2.9 1 1 1 2 2 2 2 CsbD-like Med14 PF08638.6 OAJ04009.1 - 3.2e-36 124.4 0.0 5.1e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 Kelch_4 PF13418.1 OAJ04010.1 - 2.1e-24 85.0 7.8 2.7e-10 39.8 0.0 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ04010.1 - 3.4e-20 71.6 11.0 1.2e-06 28.4 0.0 7.0 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ04010.1 - 1.1e-15 57.0 0.9 0.00043 20.3 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.1 OAJ04010.1 - 3.5e-13 49.1 0.2 0.038 13.9 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 OAJ04010.1 - 1.4e-12 46.9 0.0 5.5e-05 22.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 OAJ04010.1 - 0.002 17.8 2.5 5.1 7.0 0.1 3.9 4 0 0 4 4 4 2 Kelch motif G-alpha PF00503.15 OAJ04011.1 - 1.3e-114 382.9 0.1 1.6e-114 382.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 OAJ04011.1 - 3.7e-12 45.8 0.2 1.4e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 OAJ04011.1 - 0.00016 22.1 0.0 0.89 10.0 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 OAJ04011.1 - 0.0092 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 OAJ04011.1 - 0.01 15.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 OAJ04011.1 - 0.027 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 OAJ04011.1 - 0.041 13.0 0.2 5.1 6.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 OAJ04011.1 - 0.053 13.0 0.0 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MCM PF00493.18 OAJ04011.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family Rad1 PF02144.11 OAJ04012.1 - 3.4e-67 226.1 0.0 4.6e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 NAP PF00956.13 OAJ04013.1 - 4.8e-85 284.5 5.6 4.8e-85 284.5 3.9 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 OAJ04013.1 - 0.25 11.1 8.3 0.7 9.7 2.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_21 PF13506.1 OAJ04014.1 - 1.2e-21 76.8 0.1 9.8e-09 34.7 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 OAJ04014.1 - 2.2e-14 53.7 0.2 4.8e-13 49.4 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAJ04014.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 IMS PF00817.15 OAJ04015.1 - 7.3e-44 149.1 0.2 1.3e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 OAJ04015.1 - 1.6e-15 57.1 0.4 4.1e-15 55.8 0.3 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 OAJ04015.1 - 4.5e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PRA1 PF03208.14 OAJ04016.1 - 5.2e-39 133.0 0.4 6.1e-39 132.8 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein Med12 PF09497.5 OAJ04017.1 - 2.4e-23 81.8 0.0 6.2e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF3763 PF12592.3 OAJ04017.1 - 0.072 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) ARPC4 PF05856.7 OAJ04018.1 - 2.1e-75 251.8 4.3 2.5e-75 251.5 3.0 1.1 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UPF0172 PF03665.8 OAJ04019.1 - 1.6e-39 135.4 0.0 2.1e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) UPF0104 PF03706.8 OAJ04020.1 - 0.011 15.0 1.8 0.015 14.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4345 PF14248.1 OAJ04020.1 - 0.024 14.1 6.4 0.027 13.8 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) PepSY_TM_2 PF13703.1 OAJ04020.1 - 2.5 8.3 8.0 39 4.5 0.1 2.6 1 1 1 2 2 2 0 PepSY-associated TM helix Sugar_tr PF00083.19 OAJ04025.1 - 6.2e-98 328.2 19.0 7.9e-98 327.9 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DEAD PF00270.24 OAJ04025.1 - 9.9e-33 113.0 0.0 2.1e-31 108.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase MFS_1 PF07690.11 OAJ04025.1 - 1.5e-24 86.3 14.2 1.5e-24 86.3 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.26 OAJ04025.1 - 1.8e-17 62.9 0.0 4.1e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ04025.1 - 4e-16 58.3 0.3 7.5e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 OAJ04025.1 - 4.5e-06 26.6 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 OAJ04026.1 - 7.2e-97 320.6 0.0 1.6e-47 161.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 OAJ04026.1 - 4.6e-23 80.9 0.2 1.8e-22 79.0 0.0 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 OAJ04026.1 - 8.6e-16 57.6 0.0 2e-05 23.7 0.0 4.0 4 1 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 OAJ04026.1 - 1.6e-13 50.9 0.0 3.6e-07 30.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ04026.1 - 1.7e-13 50.6 0.1 1.9e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 OAJ04026.1 - 1.7e-12 47.2 0.2 6.1e-06 26.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAJ04026.1 - 1.4e-11 45.2 0.0 0.00041 21.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ04026.1 - 3e-11 43.6 0.2 0.0016 18.6 0.0 4.2 3 2 1 4 4 2 2 AAA domain CDC48_2 PF02933.12 OAJ04026.1 - 3.6e-10 39.3 0.0 7.7e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 OAJ04026.1 - 1.9e-09 36.7 0.1 0.0013 17.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 OAJ04026.1 - 3.5e-09 36.9 0.0 0.0056 16.6 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 OAJ04026.1 - 9.6e-09 34.6 0.0 0.0049 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 OAJ04026.1 - 2.4e-08 33.6 3.1 0.0031 16.9 0.0 4.3 3 2 1 5 5 5 2 AAA domain IstB_IS21 PF01695.12 OAJ04026.1 - 3.5e-08 33.0 0.0 0.0031 16.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ04026.1 - 3.8e-08 32.7 0.4 0.0022 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 OAJ04026.1 - 6.5e-08 32.5 0.0 0.0064 16.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_19 PF13245.1 OAJ04026.1 - 3.4e-07 29.9 1.7 0.015 15.0 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Vps4_C PF09336.5 OAJ04026.1 - 9.2e-07 28.6 0.2 4.7e-06 26.4 0.1 2.3 2 1 1 3 3 1 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.17 OAJ04026.1 - 1.1e-06 28.7 0.0 0.014 15.5 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.1 OAJ04026.1 - 2.9e-06 27.3 0.0 0.057 13.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 OAJ04026.1 - 3.6e-06 27.2 0.0 0.037 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 OAJ04026.1 - 4.8e-06 25.8 1.0 0.85 8.6 0.0 3.5 2 1 1 3 3 3 2 KaiC Parvo_NS1 PF01057.12 OAJ04026.1 - 5.3e-06 25.5 0.2 0.0053 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 OAJ04026.1 - 6.6e-06 26.0 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.8 OAJ04026.1 - 7.3e-06 25.0 0.0 0.0021 17.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 OAJ04026.1 - 1.5e-05 24.5 0.0 0.36 10.3 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 OAJ04026.1 - 1.5e-05 24.6 0.1 0.066 12.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 OAJ04026.1 - 2.1e-05 24.8 0.0 0.11 12.7 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 OAJ04026.1 - 2.4e-05 24.4 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 OAJ04026.1 - 4.8e-05 22.6 0.2 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NACHT PF05729.7 OAJ04026.1 - 5e-05 23.0 0.1 0.07 12.7 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 OAJ04026.1 - 6.1e-05 22.7 0.0 0.54 9.8 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 OAJ04026.1 - 0.0001 22.0 0.0 2.1 7.9 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 OAJ04026.1 - 0.00015 21.4 0.0 0.42 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 OAJ04026.1 - 0.00019 21.0 0.0 0.42 10.1 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 OAJ04026.1 - 0.00057 19.5 0.0 0.91 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 OAJ04026.1 - 0.00058 19.4 0.0 0.13 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 OAJ04026.1 - 0.0024 17.3 1.3 1.2 8.5 0.0 3.9 3 1 0 4 4 4 1 AAA-like domain NB-ARC PF00931.17 OAJ04026.1 - 0.0024 16.7 0.1 0.24 10.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 OAJ04026.1 - 0.0028 17.4 0.2 0.74 9.5 0.0 3.4 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 OAJ04026.1 - 0.0035 16.3 1.6 0.89 8.4 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 OAJ04026.1 - 0.0057 15.5 0.0 0.22 10.3 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein IPT PF01745.11 OAJ04026.1 - 0.021 14.0 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 OAJ04026.1 - 0.025 14.2 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 OAJ04026.1 - 0.036 13.2 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 OAJ04026.1 - 0.037 13.0 0.0 0.75 8.7 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.20 OAJ04026.1 - 0.06 12.8 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 OAJ04026.1 - 0.063 13.1 0.0 6.9 6.5 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase AFG1_ATPase PF03969.11 OAJ04026.1 - 0.07 11.9 0.0 7.6 5.2 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase MobB PF03205.9 OAJ04026.1 - 0.086 12.5 0.4 5.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 OAJ04026.1 - 0.11 12.7 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain UFD1 PF03152.9 OAJ04026.1 - 0.17 10.9 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 DUF221 PF02714.10 OAJ04027.1 - 1.5e-41 142.3 13.0 2.2e-41 141.8 9.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 OAJ04027.1 - 1.8e-13 50.3 2.8 1.8e-13 50.3 2.0 3.4 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 OAJ04027.1 - 0.00097 19.6 0.0 0.011 16.2 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 OAJ04027.1 - 0.0043 16.9 0.0 3.3 7.7 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YojJ PF10372.4 OAJ04027.1 - 0.29 11.0 0.2 1.1 9.2 0.1 1.9 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Zip PF02535.17 OAJ04028.1 - 0.0094 14.9 5.3 0.014 14.4 3.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter IBN_N PF03810.14 OAJ04029.1 - 1.4e-14 53.7 0.0 3.3e-11 42.9 0.0 3.7 3 0 0 3 3 3 2 Importin-beta N-terminal domain Cse1 PF08506.5 OAJ04029.1 - 2.4e-08 32.9 0.0 5.1e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 OAJ04029.1 - 1.4e-06 28.4 6.1 0.0027 17.9 0.1 4.2 4 0 0 4 4 4 2 HEAT repeats Xpo1 PF08389.7 OAJ04029.1 - 2.5e-05 24.2 0.1 0.0015 18.4 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 OAJ04029.1 - 0.00049 19.9 0.7 0.18 11.9 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 OAJ04029.1 - 0.0049 17.2 0.0 0.19 12.1 0.0 3.5 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region XPC-binding PF09280.6 OAJ04029.1 - 0.035 13.5 0.1 0.19 11.1 0.0 2.3 1 0 0 1 1 1 0 XPC-binding domain HTH_psq PF05225.11 OAJ04029.1 - 0.085 12.4 0.3 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain HEAT_EZ PF13513.1 OAJ04029.1 - 0.63 10.6 7.9 3 8.4 0.0 5.7 6 1 0 6 6 6 0 HEAT-like repeat Pkinase PF00069.20 OAJ04030.1 - 2.6e-37 128.3 0.0 5.3e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04030.1 - 2.1e-09 36.8 0.0 3.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04030.1 - 2e-05 24.4 0.0 7.2e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinetochor_Ybp2 PF08568.5 OAJ04030.1 - 2e-05 23.0 0.0 0.11 10.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Choline_kinase PF01633.15 OAJ04030.1 - 0.0037 16.8 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 OAJ04030.1 - 0.14 11.1 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tub_2 PF04525.7 OAJ04031.1 - 2.6e-27 95.4 0.0 3.1e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 zf-BED PF02892.10 OAJ04032.1 - 0.011 15.4 0.5 0.019 14.7 0.4 1.3 1 0 0 1 1 1 0 BED zinc finger DUF938 PF06080.7 OAJ04033.1 - 6.2e-31 107.5 0.0 1.2e-30 106.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 OAJ04033.1 - 0.0085 16.6 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ04033.1 - 0.093 13.2 0.0 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain AOX PF01786.12 OAJ04034.1 - 9e-80 266.9 0.0 1.1e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase FA_hydroxylase PF04116.8 OAJ04036.1 - 1e-13 51.6 26.8 1.2e-13 51.4 15.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.14 OAJ04036.1 - 0.08 13.3 4.0 0.13 12.6 2.8 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pinin_SDK_memA PF04696.8 OAJ04037.1 - 8.6e-09 35.0 5.1 8.6e-09 35.0 3.5 3.0 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region TPR_MLP1_2 PF07926.7 OAJ04037.1 - 3.8 7.2 12.0 1.2 8.9 2.0 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PP2C PF00481.16 OAJ04038.1 - 2.2e-81 273.0 0.3 4.1e-81 272.1 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Peptidase_C1_2 PF03051.10 OAJ04039.1 - 8.3e-138 459.5 0.0 2.7e-136 454.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 OAJ04039.1 - 4.6e-07 29.9 0.3 0.0012 18.7 0.3 2.5 2 0 0 2 2 2 2 Papain family cysteine protease SDA1 PF05285.7 OAJ04040.1 - 9e-71 238.7 44.2 9e-71 238.7 30.6 3.3 3 1 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 OAJ04040.1 - 7e-16 58.2 0.1 1.3e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 NUC130/3NT domain RRM_1 PF00076.17 OAJ04041.1 - 5.1e-34 115.7 0.0 9.6e-17 60.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04041.1 - 1.1e-25 89.3 0.0 7.7e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04041.1 - 5.7e-10 38.8 0.0 0.00033 20.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Scs3p PF10261.4 OAJ04042.1 - 1.9e-46 158.0 0.0 3.6e-46 157.1 0.0 1.4 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PH_10 PF15411.1 OAJ04046.1 - 1.4e-21 76.8 0.0 2.6e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 OAJ04046.1 - 2.5e-07 30.5 0.0 5.4e-06 26.1 0.0 2.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Mpp10 PF04006.7 OAJ04047.1 - 2.9e-81 273.6 81.8 1.8e-73 247.9 39.9 3.2 1 1 0 2 2 2 2 Mpp10 protein SNF2_N PF00176.18 OAJ04048.1 - 4.3e-63 212.8 0.0 5.8e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ04048.1 - 1.8e-13 50.1 0.0 4.3e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ04048.1 - 7.6e-09 35.2 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ04048.1 - 6.2e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 OAJ04048.1 - 4.9e-05 22.2 0.0 0.00013 20.9 0.0 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 OAJ04048.1 - 0.076 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_1 PF00515.23 OAJ04049.1 - 1.6e-26 90.7 14.5 9.2e-06 25.0 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ04049.1 - 2.8e-23 79.9 21.7 0.0013 18.4 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ04049.1 - 5.5e-23 78.9 11.1 8.5e-05 22.0 0.0 8.8 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ04049.1 - 9.6e-23 79.6 14.2 4.8e-10 38.9 0.5 6.4 4 1 2 6 6 6 5 TPR repeat APC8 PF04049.8 OAJ04049.1 - 6.1e-18 64.9 2.9 1.7e-16 60.2 2.0 2.5 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.1 OAJ04049.1 - 5.1e-17 60.8 18.3 0.0017 18.8 0.1 9.7 5 3 3 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04049.1 - 2.4e-14 53.0 19.9 9.4e-05 22.2 0.1 7.2 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ04049.1 - 4.5e-14 51.4 4.7 0.00025 20.9 0.0 7.6 8 1 1 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ04049.1 - 6.8e-14 51.7 8.2 0.00025 21.1 0.1 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 OAJ04049.1 - 1e-12 48.2 9.6 0.0024 18.1 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04049.1 - 1.1e-10 41.9 25.1 1.9e-05 25.2 0.0 7.5 4 2 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ04049.1 - 3.3e-10 38.9 16.7 0.0012 18.4 0.0 7.7 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ04049.1 - 1.5e-05 24.7 10.9 0.16 11.8 0.1 5.7 2 1 5 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ04049.1 - 6.5e-05 22.1 4.7 0.49 9.4 0.0 4.4 2 2 3 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.5 OAJ04049.1 - 0.0016 17.2 0.0 0.11 11.2 0.0 2.6 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 OAJ04049.1 - 0.0031 16.7 0.0 0.24 10.5 0.0 3.2 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.1 OAJ04049.1 - 0.0053 17.1 20.7 21 5.8 0.1 9.0 10 1 1 11 11 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 OAJ04049.1 - 3.2 7.6 6.7 91 3.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DENN PF02141.16 OAJ04050.1 - 7.7e-23 81.1 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF3450 PF11932.3 OAJ04050.1 - 0.011 15.0 6.7 0.024 13.8 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.9 OAJ04050.1 - 0.33 10.8 9.5 0.09 12.7 3.7 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 OAJ04050.1 - 0.47 8.8 7.5 0.49 8.7 2.1 2.1 2 0 0 2 2 2 0 AAA domain Myosin_tail_1 PF01576.14 OAJ04050.1 - 0.65 7.6 20.3 0.049 11.3 10.4 1.6 2 0 0 2 2 2 0 Myosin tail Syntaxin PF00804.20 OAJ04050.1 - 0.72 10.0 13.2 1.9 8.6 1.1 2.8 2 0 0 2 2 2 0 Syntaxin GAS PF13851.1 OAJ04050.1 - 0.88 8.7 14.3 0.16 11.1 7.0 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 OAJ04050.1 - 1.6 7.7 13.4 0.092 11.7 5.3 1.7 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 OAJ04050.1 - 1.7 8.2 14.8 0.34 10.4 5.4 2.4 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 OAJ04050.1 - 2.2 7.1 14.1 2.8 6.7 4.2 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 OAJ04050.1 - 3.2 5.4 1.6 6 4.5 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 OAJ04050.1 - 3.7 7.4 19.5 2.2 8.1 2.2 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 OAJ04050.1 - 5.1 6.9 6.5 12 5.6 0.2 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus UQ_con PF00179.21 OAJ04051.1 - 1.5e-41 141.0 0.0 1.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ04051.1 - 0.0012 18.7 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 OAJ04051.1 - 0.0037 17.0 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Sec7 PF01369.15 OAJ04058.1 - 2.2e-65 219.8 0.0 5.3e-65 218.6 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ04058.1 - 2.6e-52 176.6 5.7 2.6e-52 176.6 3.9 2.0 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ04058.1 - 1.1e-24 85.7 0.1 1.7e-23 81.9 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DUF3730 PF12530.3 OAJ04058.1 - 0.0017 18.3 0.2 0.0017 18.3 0.1 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) GDI PF00996.13 OAJ04059.1 - 4.3e-47 160.4 0.0 1e-46 159.1 0.0 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor GMC_oxred_N PF00732.14 OAJ04059.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase PBP1_TM PF14812.1 OAJ04059.1 - 2.7 8.3 7.2 5.5 7.3 5.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rgp1 PF08737.5 OAJ04060.1 - 1.2e-68 232.1 0.0 1.3e-67 228.7 0.0 2.1 1 1 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 OAJ04060.1 - 4.5e-06 26.5 1.7 0.025 14.3 0.0 3.8 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SopA_C PF13979.1 OAJ04060.1 - 0.013 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 SopA-like catalytic domain DPBB_1 PF03330.13 OAJ04061.1 - 0.00012 21.9 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ECR1_N PF14382.1 OAJ04062.1 - 5.9e-06 25.4 0.0 1.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 OAJ04062.1 - 0.0045 16.8 0.0 0.11 12.5 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 CN_hydrolase PF00795.17 OAJ04063.1 - 8e-24 84.0 0.0 1.1e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LRR_4 PF12799.2 OAJ04064.1 - 8.5e-10 38.0 2.9 7.7e-09 34.9 0.4 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ04064.1 - 1.4e-09 37.5 1.8 3e-09 36.4 1.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 OAJ04064.1 - 3.9e-07 29.1 1.8 0.15 12.2 0.1 3.8 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ04064.1 - 0.00043 20.0 2.1 3 8.4 0.1 3.8 3 0 0 3 3 3 1 Leucine rich repeat PH PF00169.24 OAJ04065.1 - 1.8e-08 34.5 0.1 3.3e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ04065.1 - 0.084 13.1 1.6 0.1 12.8 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_3 PF07859.8 OAJ04066.1 - 1.5e-19 70.4 0.2 7.1e-18 64.9 0.1 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ04066.1 - 1e-09 37.5 0.0 8.3e-07 27.9 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Nucleo_P87 PF07267.6 OAJ04066.1 - 0.51 8.9 2.3 1.2 7.7 1.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HAUS6_N PF14661.1 OAJ04066.1 - 1.4 8.1 5.8 2.6 7.3 4.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ycf1 PF05758.7 OAJ04066.1 - 2.7 5.5 1.9 3.9 5.0 1.3 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 OAJ04066.1 - 6.5 4.3 4.8 12 3.4 3.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LSM PF01423.17 OAJ04067.1 - 2.3e-16 59.0 0.2 3.3e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain HAUS-augmin3 PF14932.1 OAJ04067.1 - 0.025 13.7 0.3 0.031 13.4 0.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FSA_C PF10479.4 OAJ04067.1 - 0.047 11.7 0.1 0.056 11.5 0.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3296 PF11726.3 OAJ04067.1 - 0.072 12.6 0.0 0.08 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) PCI PF01399.22 OAJ04068.1 - 2.8e-05 24.3 0.0 6.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rot1 PF10681.4 OAJ04069.1 - 2.1e-51 174.2 2.3 2.7e-51 173.9 1.6 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Methyltransf_8 PF05148.10 OAJ04070.1 - 4.6e-52 176.8 0.0 1.1e-26 93.8 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase DUF3140 PF11338.3 OAJ04070.1 - 4.1e-28 97.3 1.5 4.1e-28 97.3 1.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3140) Methyltransf_11 PF08241.7 OAJ04070.1 - 0.004 17.6 0.0 0.19 12.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ04070.1 - 0.015 14.9 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain RFC1 PF08519.7 OAJ04071.1 - 7.7e-51 171.9 0.0 1.8e-50 170.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 OAJ04071.1 - 4.5e-10 39.5 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 OAJ04071.1 - 4.8e-10 39.7 0.1 3.7e-09 36.8 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ04071.1 - 2.8e-08 32.9 0.0 9e-07 27.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAJ04071.1 - 0.00062 19.9 0.0 0.0071 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ04071.1 - 0.00082 20.1 0.0 0.00082 20.1 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 OAJ04071.1 - 0.0012 18.7 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ04071.1 - 0.002 18.1 0.0 0.0051 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 OAJ04071.1 - 0.0029 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 OAJ04071.1 - 0.0053 17.0 0.0 0.0053 17.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ04071.1 - 0.0056 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 OAJ04071.1 - 0.01 15.4 0.4 0.59 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.8 OAJ04071.1 - 0.017 14.6 0.6 0.044 13.3 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit NTPase_1 PF03266.10 OAJ04071.1 - 0.036 13.7 0.1 0.28 10.8 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 OAJ04071.1 - 0.056 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IPP-2 PF04979.9 OAJ04072.1 - 8.1e-11 42.2 9.3 0.00021 21.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) WW PF00397.21 OAJ04073.1 - 0.0033 17.2 0.6 0.0072 16.1 0.4 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 OAJ04073.1 - 1.5 8.8 30.4 0.44 10.5 13.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TRAM_LAG1_CLN8 PF03798.11 OAJ04075.1 - 3.3e-32 111.6 11.5 3.3e-32 111.6 8.0 1.4 2 0 0 2 2 2 1 TLC domain CH PF00307.26 OAJ04077.1 - 1.2e-67 224.7 0.0 1.2e-17 63.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 OAJ04077.1 - 1.3e-06 27.9 0.0 1.4 8.6 0.0 4.1 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 OAJ04077.1 - 0.00026 21.0 0.3 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 OAJ04077.1 - 0.00076 18.6 0.2 0.37 10.2 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 OAJ04077.1 - 0.068 13.0 1.7 7.3 6.7 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain FAD_binding_6 PF00970.19 OAJ04079.1 - 7.5e-07 29.1 0.0 9.9e-06 25.6 0.0 2.7 4 0 0 4 4 4 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ04079.1 - 7.3e-05 23.2 0.0 0.031 14.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAJ04079.1 - 0.0096 15.8 0.0 0.042 13.7 0.0 2.0 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Pkinase PF00069.20 OAJ04080.1 - 1.4e-28 99.7 0.0 7e-19 67.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04080.1 - 1.1e-12 47.6 0.0 5.3e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04080.1 - 0.001 18.1 0.0 0.73 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DAGAT PF03982.8 OAJ04082.1 - 2.2e-96 322.0 0.0 8.7e-52 175.6 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Glyco_trans_2_3 PF13632.1 OAJ04082.1 - 0.013 15.1 0.6 0.63 9.7 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Urm1 PF09138.6 OAJ04083.1 - 1.2e-31 108.7 0.0 2e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.17 OAJ04083.1 - 1.7e-24 86.7 0.3 3e-23 82.6 0.1 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) ThiS PF02597.15 OAJ04083.1 - 0.073 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 ThiS family VMA21 PF09446.5 OAJ04085.1 - 2.5e-10 40.1 7.8 3.6e-10 39.6 5.4 1.2 1 0 0 1 1 1 1 VMA21-like domain polyprenyl_synt PF00348.12 OAJ04086.1 - 2.6e-70 236.2 0.0 3.4e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Spermine_synth PF01564.12 OAJ04087.1 - 0.19 10.6 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase MF_alpha_N PF05436.6 OAJ04087.1 - 0.73 9.5 3.2 0.32 10.7 0.6 1.6 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus AF0941-like PF14591.1 OAJ04088.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 AF0941-like zf-HIT PF04438.11 OAJ04089.1 - 1e-07 31.4 9.7 1.6e-07 30.8 6.8 1.2 1 0 0 1 1 1 1 HIT zinc finger Trypan_PARP PF05887.6 OAJ04090.1 - 0.12 12.1 4.6 0.18 11.6 3.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PWI PF01480.12 OAJ04096.1 - 1.6e-26 92.1 0.0 2.5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 PWI domain Pkinase PF00069.20 OAJ04097.1 - 5.8e-63 212.4 0.0 8.1e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04097.1 - 5.8e-28 97.6 0.0 1.1e-27 96.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ04097.1 - 1.9e-07 31.4 0.2 1.9e-07 31.4 0.1 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 OAJ04097.1 - 0.003 16.6 0.0 0.0067 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ04097.1 - 0.15 11.0 0.1 1.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Hs1pro-1_C PF07014.7 OAJ04097.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Tim54 PF11711.3 OAJ04098.1 - 1.1e-49 169.0 0.0 2.3e-49 168.0 0.0 1.4 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 GTP_EFTU PF00009.22 OAJ04099.1 - 1e-59 201.1 0.8 1.9e-59 200.2 0.5 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ04099.1 - 2.8e-28 97.9 0.0 6.5e-28 96.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ04099.1 - 2.3e-17 62.8 2.5 2.3e-17 62.8 1.7 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ04099.1 - 1.3e-05 25.1 0.1 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ04099.1 - 0.0046 17.4 0.1 0.0087 16.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 OAJ04099.1 - 0.041 13.3 0.5 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 OAJ04099.1 - 0.046 13.1 1.5 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain adh_short_C2 PF13561.1 OAJ04100.1 - 1.7e-25 90.1 0.0 2.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ04100.1 - 2.1e-23 83.0 0.0 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ04100.1 - 4e-08 33.1 0.0 5.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ04100.1 - 0.0017 18.0 0.1 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DDOST_48kD PF03345.9 OAJ04101.1 - 4.5e-86 289.0 0.0 2.7e-57 194.1 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta DUF937 PF06078.6 OAJ04101.1 - 0.0039 17.4 0.4 0.0066 16.6 0.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) 4HBT PF03061.17 OAJ04103.1 - 1.7e-05 24.8 0.2 0.12 12.5 0.0 2.8 2 1 0 2 2 2 2 Thioesterase superfamily Apolipoprotein PF01442.13 OAJ04104.1 - 0.048 13.1 2.1 0.086 12.3 1.5 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fungal_trans PF04082.13 OAJ04105.1 - 1.1e-08 34.2 0.1 1.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ04105.1 - 4.9e-08 32.7 10.4 8.3e-08 32.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mid1 PF12929.2 OAJ04106.1 - 1.3e-59 202.0 0.0 2.6e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component DUF3357 PF11837.3 OAJ04106.1 - 0.01 15.6 1.4 0.03 14.1 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Glyco_hydro_45 PF02015.11 OAJ04108.1 - 1.6e-50 172.0 6.8 2e-50 171.6 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Sel1 PF08238.7 OAJ04111.1 - 4.5e-11 43.0 17.6 3.1e-09 37.1 0.4 5.7 6 0 0 6 6 6 2 Sel1 repeat TPR_2 PF07719.12 OAJ04111.1 - 0.004 16.9 0.7 0.82 9.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Lipase_3 PF01764.20 OAJ04112.1 - 1.1e-19 70.4 0.1 1.7e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ04112.1 - 0.012 15.3 0.1 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Amido_AtzD_TrzD PF09663.5 OAJ04112.1 - 0.067 11.7 0.1 0.093 11.2 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Lipase_3 PF01764.20 OAJ04113.1 - 1.4e-22 79.7 0.0 2.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase_3 PF01764.20 OAJ04114.1 - 1.4e-22 79.7 0.0 2.2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Phage_integrase PF00589.17 OAJ04115.1 - 0.00092 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family RVT_3 PF13456.1 OAJ04117.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 OAJ04117.1 - 0.023 14.0 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) LSM PF01423.17 OAJ04118.1 - 1.5e-20 72.4 0.1 1.9e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Phosphodiest PF01663.17 OAJ04119.1 - 3e-05 23.5 0.2 7.1e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase RVT_1 PF00078.22 OAJ04120.1 - 4.9e-32 111.0 0.0 1.3e-31 109.6 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 OAJ04120.1 - 1.2e-05 25.3 0.3 4.1e-05 23.6 0.2 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ04120.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase PAM2 PF07145.10 OAJ04120.1 - 0.46 10.0 6.1 0.092 12.2 1.0 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Glyco_hydro_2 PF00703.16 OAJ04122.1 - 3.1e-10 40.4 0.2 6.8e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 PKD PF00801.15 OAJ04122.1 - 0.015 15.0 0.2 0.015 15.0 0.1 3.4 3 1 0 3 3 3 0 PKD domain Glyco_hydro_2_C PF02836.12 OAJ04122.1 - 0.054 12.3 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Membr_traf_MHD PF10540.4 OAJ04123.1 - 2e-14 53.5 0.0 5.7e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 OAJ04123.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Sec6 PF06046.8 OAJ04123.1 - 0.0036 15.4 0.0 0.017 13.2 0.0 2.0 3 0 0 3 3 3 1 Exocyst complex component Sec6 AAA_32 PF13654.1 OAJ04123.1 - 0.072 11.7 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain CRCB PF02537.10 OAJ04124.1 - 2.8e-23 82.0 12.8 2.9e-15 56.1 1.8 3.0 2 1 0 2 2 2 2 CrcB-like protein Herpes_UL45 PF05473.7 OAJ04124.1 - 0.02 14.3 0.1 0.072 12.4 0.0 1.9 2 0 0 2 2 2 0 UL45 protein EIID-AGA PF03613.9 OAJ04124.1 - 0.055 12.3 1.0 2.5 6.9 0.1 3.2 3 0 0 3 3 3 0 PTS system mannose/fructose/sorbose family IID component KdpC PF02669.10 OAJ04125.1 - 0.25 11.0 1.2 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Barwin PF00967.12 OAJ04128.1 - 0.01 15.5 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 Barwin family Adeno_PIX PF03955.9 OAJ04129.1 - 0.011 16.2 0.6 0.011 16.2 0.4 1.8 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF746 PF05344.6 OAJ04129.1 - 0.026 14.0 0.5 0.051 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) NTR2 PF15458.1 OAJ04129.1 - 0.033 13.4 0.1 0.044 13.0 0.1 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 SOCS_box PF07525.11 OAJ04129.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 SOCS box Macoilin PF09726.4 OAJ04129.1 - 0.92 7.7 7.0 1.2 7.2 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Wzt_C PF14524.1 OAJ04130.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Wzt C-terminal domain PIF1 PF05970.9 OAJ04133.1 - 2.3e-33 115.6 0.0 3.8e-31 108.3 0.0 2.2 1 1 1 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 OAJ04133.1 - 4.3e-31 108.0 0.5 1.1e-30 106.7 0.3 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ04133.1 - 0.0062 16.1 0.0 0.53 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 OAJ04133.1 - 0.11 11.4 0.0 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PNGaseA PF12222.3 OAJ04136.1 - 1.4e-56 192.1 1.4 1.8e-38 132.5 0.3 2.2 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Pkinase PF00069.20 OAJ04137.1 - 7.3e-39 133.4 0.0 1.2e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04137.1 - 1.4e-25 89.9 0.0 2.1e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04137.1 - 0.0097 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ04137.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like B-block_TFIIIC PF04182.7 OAJ04138.1 - 8.7e-10 38.3 0.1 3.5e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC DUF3079 PF11278.3 OAJ04139.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) IATP PF04568.7 OAJ04140.1 - 6.4e-13 48.5 0.1 6.8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP YgaB PF14182.1 OAJ04140.1 - 0.14 12.4 1.7 0.18 12.0 1.2 1.1 1 0 0 1 1 1 0 YgaB-like protein CAF1 PF04857.15 OAJ04142.1 - 2.1e-64 217.4 0.0 3.1e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Peptidase_M24 PF00557.19 OAJ04143.1 - 9.1e-43 146.2 0.0 1.1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 STE3 PF02076.10 OAJ04144.1 - 8.5e-93 310.5 10.2 1.1e-92 310.0 7.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor VWA_2 PF13519.1 OAJ04145.1 - 4.1e-17 62.8 0.3 5.9e-17 62.3 0.1 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 OAJ04145.1 - 7.6e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 OAJ04145.1 - 0.011 15.1 16.9 0.027 14.0 0.2 3.4 3 0 0 3 3 3 0 Ubiquitin interaction motif DUF4362 PF14275.1 OAJ04145.1 - 0.1 12.6 0.3 0.29 11.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) SSP160 PF06933.6 OAJ04145.1 - 0.45 8.4 4.2 0.67 7.8 2.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WD40 PF00400.27 OAJ04146.1 - 1.2e-22 78.9 18.1 4.3e-06 26.3 0.7 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 OAJ04146.1 - 0.021 14.5 0.1 2.5 7.7 0.0 3.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Dimer_Tnp_hAT PF05699.9 OAJ04147.1 - 1.6e-15 56.4 0.0 3e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PGM_PMM_IV PF00408.15 OAJ04147.1 - 0.027 14.4 0.2 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Histone PF00125.19 OAJ04148.1 - 6.2e-21 74.3 0.1 1.6e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 OAJ04148.1 - 9.2e-06 25.3 0.0 6.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.1 OAJ04148.1 - 0.0032 17.5 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ04148.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 OAJ04148.1 - 0.0056 15.9 0.1 0.0056 15.9 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T Dimer_Tnp_hAT PF05699.9 OAJ04149.1 - 2.5e-07 30.1 0.0 7.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region YecR PF13992.1 OAJ04149.1 - 0.07 13.3 0.6 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 YecR-like lipoprotein Pkinase PF00069.20 OAJ04150.1 - 3.8e-47 160.6 0.0 5.4e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04150.1 - 1.4e-28 99.6 0.0 2.3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Daxx PF03344.10 OAJ04150.1 - 0.0043 15.6 0.8 0.0062 15.0 0.5 1.1 1 0 0 1 1 1 1 Daxx Family Kdo PF06293.9 OAJ04150.1 - 0.0083 15.2 0.1 0.02 13.9 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAP_assoc PF03828.14 OAJ04151.1 - 8.9e-17 60.8 0.2 1.6e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 OAJ04151.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Asp PF00026.18 OAJ04154.1 - 7.3e-11 41.8 0.0 1.6e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Cutinase PF01083.17 OAJ04155.1 - 5.6e-26 91.3 0.0 6.8e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 OAJ04155.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ04155.1 - 0.037 13.8 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ04155.1 - 0.042 13.6 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.6 OAJ04155.1 - 0.086 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF1620 PF07774.8 OAJ04156.1 - 1.7e-57 194.1 0.0 2.9e-57 193.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 OAJ04156.1 - 4.4e-09 36.1 7.9 4.8e-05 22.9 0.3 4.3 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 OAJ04156.1 - 3.4e-06 26.3 2.3 0.33 10.5 0.0 5.6 6 0 0 6 6 6 2 PQQ enzyme repeat adh_short PF00106.20 OAJ04157.1 - 6.1e-26 91.3 0.1 7.7e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ04157.1 - 3e-20 73.0 0.0 4.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ04157.1 - 4.4e-17 62.3 0.1 1.2e-16 60.9 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 OAJ04157.1 - 0.00013 21.5 0.1 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ04157.1 - 0.02 14.9 0.2 0.043 13.8 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 OAJ04157.1 - 0.035 13.7 1.5 0.062 12.9 0.5 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding PF02629.14 OAJ04157.1 - 0.058 13.8 0.4 3.4 8.2 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain GHMP_kinases_C PF08544.8 OAJ04157.1 - 0.071 13.3 0.1 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal PS_Dcarbxylase PF02666.10 OAJ04158.1 - 8e-41 139.5 0.0 1.1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Asp PF00026.18 OAJ04159.1 - 3.5e-12 46.2 0.0 5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ATP_sub_h PF10775.4 OAJ04160.1 - 7.2e-23 80.0 0.8 1.1e-22 79.5 0.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 OAJ04160.1 - 0.0034 17.2 0.1 0.0079 16.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 HTH_13 PF11972.3 OAJ04160.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Got1 PF04178.7 OAJ04161.1 - 6.9e-22 77.7 11.9 9.7e-22 77.2 8.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2627 PF11118.3 OAJ04161.1 - 0.82 9.8 4.0 0.51 10.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) adh_short PF00106.20 OAJ04163.1 - 0.039 13.8 0.1 0.14 12.0 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase RTA1 PF04479.8 OAJ04164.1 - 1.3e-31 109.8 3.4 3.4e-25 88.8 0.2 2.1 2 0 0 2 2 2 2 RTA1 like protein OAD_gamma PF04277.8 OAJ04164.1 - 0.056 13.8 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain ApoO PF09769.4 OAJ04165.1 - 1.7e-32 112.3 0.4 2.8e-32 111.6 0.3 1.3 1 0 0 1 1 1 1 Apolipoprotein O DUF883 PF05957.8 OAJ04165.1 - 0.004 17.5 0.3 3.7 8.0 0.0 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 OAJ04165.1 - 0.0052 16.3 2.0 0.16 11.4 0.1 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Phasin PF05597.6 OAJ04165.1 - 2.6 7.8 6.3 12 5.6 0.2 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HMGL-like PF00682.14 OAJ04166.1 - 1.4e-39 136.2 0.4 8.1e-39 133.6 0.3 2.1 1 1 0 1 1 1 1 HMGL-like Apc5 PF12862.2 OAJ04167.1 - 6.9e-15 54.6 2.5 2.2e-14 53.0 1.0 2.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 OAJ04167.1 - 0.074 12.9 7.8 1.6 8.7 0.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc1 PF12859.2 OAJ04168.1 - 9.2e-15 54.7 0.0 6.9e-14 51.9 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 OAJ04168.1 - 0.0029 17.7 11.3 0.23 11.7 0.0 5.8 6 0 0 6 6 6 2 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.1 OAJ04169.1 - 3.1e-23 80.9 0.0 4.3e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ04169.1 - 2.8e-10 39.1 0.0 3.7e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Gly-zipper_OmpA PF13436.1 OAJ04169.1 - 0.0029 17.2 2.3 0.0039 16.8 1.6 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain NIR_SIR PF01077.17 OAJ04173.1 - 1.1e-29 102.7 0.0 2.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ04173.1 - 2.6e-26 92.7 0.2 6.6e-26 91.4 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ04173.1 - 1.8e-16 60.3 7.4 1.8e-13 50.6 0.7 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 OAJ04173.1 - 3.8e-16 58.8 2.6 3.8e-11 42.8 2.9 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 OAJ04173.1 - 1.2e-15 57.0 0.0 3.7e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.12 OAJ04173.1 - 8.7e-13 47.6 0.0 1.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ04173.1 - 6.3e-11 41.7 0.0 2.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ04173.1 - 1.1e-07 32.0 1.5 0.00093 19.3 0.1 4.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ04173.1 - 1.2e-05 25.1 5.1 0.17 11.6 0.0 3.8 3 1 1 4 4 4 3 FAD-NAD(P)-binding DAO PF01266.19 OAJ04173.1 - 9.6e-05 21.4 3.5 0.025 13.4 0.1 4.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 OAJ04173.1 - 0.00019 20.4 0.0 0.079 11.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 OAJ04173.1 - 0.003 16.4 4.5 0.37 9.5 0.1 3.0 1 1 1 2 2 2 2 FAD binding domain TrkA_N PF02254.13 OAJ04173.1 - 0.017 15.0 1.4 1.9 8.4 0.2 2.8 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 OAJ04173.1 - 0.23 11.5 1.4 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 OAJ04173.1 - 1 9.4 3.3 1.2 9.2 0.1 2.6 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAJ04173.1 - 1.9 7.2 4.9 12 4.6 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A PAC2 PF09754.4 OAJ04174.1 - 2.8e-24 86.1 0.0 3.9e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 PAC2 family Aminotran_1_2 PF00155.16 OAJ04175.1 - 3.2e-35 121.7 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ04175.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ04176.1 - 1.7e-33 116.0 0.0 2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ04176.1 - 0.0063 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Oxysterol_BP PF01237.13 OAJ04177.1 - 6.2e-86 288.0 0.0 8.5e-86 287.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein MutS_V PF00488.16 OAJ04178.1 - 1.5e-70 237.2 0.0 1.7e-69 233.7 0.0 2.2 1 1 1 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ04178.1 - 3.1e-44 151.2 0.0 8.3e-44 149.8 0.0 1.8 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAJ04178.1 - 1.6e-18 66.7 0.0 3.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 OAJ04178.1 - 1.5e-09 37.9 0.1 1e-08 35.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II ATG2_CAD PF13329.1 OAJ04178.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif MFS_1 PF07690.11 OAJ04179.1 - 4.1e-30 104.6 28.2 6.7e-30 103.9 19.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.14 OAJ04180.1 - 3.7e-47 159.8 0.0 6.4e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 OAJ04180.1 - 6e-42 142.3 0.2 1.1e-41 141.5 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 OAJ04180.1 - 5.4e-25 87.3 0.0 1.7e-24 85.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 OAJ04180.1 - 3.9e-21 74.6 0.0 7.8e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 OAJ04180.1 - 1.5e-20 73.7 0.0 4.7e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAJ04180.1 - 0.00086 19.2 0.0 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain bZIP_1 PF00170.16 OAJ04181.1 - 0.00031 20.6 10.1 0.00031 20.6 7.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor BAF1_ABF1 PF04684.8 OAJ04181.1 - 0.0061 15.4 26.2 0.0061 15.4 18.2 3.1 2 1 1 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor DUF2029 PF09594.5 OAJ04181.1 - 0.027 13.9 0.6 0.041 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) CD20 PF04103.10 OAJ04181.1 - 0.14 12.0 0.7 0.74 9.7 0.4 1.9 2 0 0 2 2 2 0 CD20-like family TPPK_C PF12555.3 OAJ04181.1 - 0.16 11.6 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Serinc PF03348.10 OAJ04181.1 - 0.64 8.6 3.7 1 8.0 2.6 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2749 PF10907.3 OAJ04181.1 - 1.5 8.7 5.8 1 9.2 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) RAB3GAP2_N PF14655.1 OAJ04181.1 - 1.6 7.6 9.0 2.6 6.9 6.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med13_N PF11597.3 OAJ04181.1 - 2.6 6.6 13.2 1 7.9 7.3 1.7 2 0 0 2 2 2 0 Mediator complex subunit 13 N-terminal DUF3357 PF11837.3 OAJ04181.1 - 3.9 7.3 7.1 0.48 10.2 0.2 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DUF3505 PF12013.3 OAJ04182.1 - 3.1e-06 27.3 1.3 3.4e-05 24.0 0.9 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3505) zf-HC5HC2H_2 PF13832.1 OAJ04183.1 - 1.4e-18 66.8 1.3 1.4e-18 66.8 0.9 4.2 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ04183.1 - 1.4e-15 57.2 1.2 1.4e-15 57.2 0.8 4.4 5 0 0 5 5 5 1 PHD-like zinc-binding domain PHD PF00628.24 OAJ04183.1 - 2.1e-12 46.5 25.0 4e-09 36.0 4.7 5.1 7 0 0 7 7 7 3 PHD-finger BAH PF01426.13 OAJ04183.1 - 2.3e-07 30.5 0.0 6.6e-07 29.0 0.0 1.7 2 0 0 2 2 2 1 BAH domain GATA PF00320.22 OAJ04183.1 - 6.6e-06 25.3 4.1 6.6e-06 25.3 2.8 4.2 4 0 0 4 4 4 1 GATA zinc finger PHD_2 PF13831.1 OAJ04183.1 - 0.00015 21.0 5.6 0.00015 21.0 3.8 5.5 6 0 0 6 6 6 2 PHD-finger DUF498 PF04430.9 OAJ04184.1 - 6.4e-25 86.8 0.0 1.1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Cyclin_C PF02984.14 OAJ04184.1 - 0.82 9.6 3.7 1.3 8.9 2.5 1.3 1 0 0 1 1 1 0 Cyclin, C-terminal domain Cyclin PF08613.6 OAJ04185.1 - 7.9e-13 49.0 0.0 2.1e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ04185.1 - 0.00015 21.3 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 OAJ04186.1 - 2.8e-06 27.0 6.8 7.9e-05 22.3 0.4 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.4 OAJ04186.1 - 0.12 12.0 0.0 24 4.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) TPR_1 PF00515.23 OAJ04188.1 - 3.3e-54 178.4 19.1 3.3e-07 29.6 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ04188.1 - 4.1e-49 160.5 17.5 5.9e-06 25.8 0.0 10.7 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ04188.1 - 3.9e-48 160.9 19.4 3.2e-11 42.7 0.1 7.0 4 3 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 OAJ04188.1 - 4.2e-32 107.4 14.2 0.00022 20.7 0.0 10.2 7 1 3 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ04188.1 - 7.8e-32 106.8 12.3 0.00014 21.7 0.2 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ04188.1 - 1.2e-28 96.9 19.2 0.00093 19.6 0.0 10.5 4 3 7 11 11 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ04188.1 - 1.8e-27 92.9 4.6 0.011 15.4 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04188.1 - 2.2e-26 91.9 38.6 1.8e-07 31.6 0.0 8.6 8 1 1 9 9 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04188.1 - 8.1e-26 89.7 15.2 1.7e-06 27.8 0.4 6.9 1 1 8 9 9 9 9 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ04188.1 - 1.1e-25 89.6 12.4 5.7e-07 29.7 0.0 7.3 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ04188.1 - 9e-17 60.3 22.5 0.0014 18.9 0.0 10.6 11 0 0 11 11 10 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ04188.1 - 3.4e-13 49.5 5.2 2.8e-05 24.1 0.2 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAJ04188.1 - 4.6e-13 48.8 11.3 0.0057 16.4 0.2 7.0 2 1 6 9 9 8 6 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ04188.1 - 3.5e-07 29.5 8.7 0.0021 17.1 0.4 4.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ04188.1 - 0.032 14.3 0.0 0.032 14.3 0.0 4.1 5 1 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.5 OAJ04188.1 - 0.1 11.3 1.1 5.5 5.6 0.1 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 OAJ04188.1 - 0.23 11.4 14.0 2 8.4 0.2 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat SKN1 PF03935.10 OAJ04190.1 - 2.5e-184 613.1 3.0 3e-184 612.8 2.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ04190.1 - 2.3e-06 27.0 0.2 0.00035 19.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Aminotran_4 PF01063.14 OAJ04192.1 - 6e-20 71.6 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV tRNA_U5-meth_tr PF05958.6 OAJ04193.1 - 5.7e-17 61.4 0.0 1.3e-15 56.9 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 OAJ04193.1 - 1.6e-07 31.0 0.0 3.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 OAJ04193.1 - 8.8e-07 28.6 0.8 2.1e-06 27.4 0.6 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.5 OAJ04193.1 - 3.6e-06 26.6 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 OAJ04193.1 - 1.3e-05 25.2 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ04193.1 - 4.9e-05 23.8 0.0 0.00015 22.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ04193.1 - 0.00043 19.6 0.4 0.0012 18.2 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase small domain Met_10 PF02475.11 OAJ04193.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 OAJ04193.1 - 0.023 13.8 0.1 0.057 12.5 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 OAJ04193.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Cons_hypoth95 PF03602.10 OAJ04193.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CHCH PF06747.8 OAJ04195.1 - 1.2e-06 28.2 5.4 1.9e-06 27.6 3.8 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 OAJ04195.1 - 0.016 15.1 3.5 0.14 12.2 2.7 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 OAJ04195.1 - 0.066 13.2 0.9 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb SR-25 PF10500.4 OAJ04195.1 - 0.15 11.5 1.9 0.15 11.4 1.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cmc1 PF08583.5 OAJ04195.1 - 0.28 10.9 5.3 0.53 10.1 3.7 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 OAJ04195.1 - 0.39 10.5 2.0 3.3 7.6 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 OAJ04195.1 - 0.68 9.9 4.6 2.4 8.2 0.4 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) EMP24_GP25L PF01105.19 OAJ04196.1 - 6.9e-52 175.8 0.0 8.7e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GTP_cyclohydro2 PF00925.15 OAJ04196.1 - 0.13 11.5 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II Rer1 PF03248.8 OAJ04196.1 - 0.35 10.4 1.5 17 4.9 0.4 2.1 2 0 0 2 2 2 0 Rer1 family Ras PF00071.17 OAJ04197.1 - 8.1e-51 171.6 0.1 9.7e-51 171.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ04197.1 - 5.4e-17 62.3 0.0 8.2e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ04197.1 - 1e-11 44.3 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ04197.1 - 0.00025 20.2 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 OAJ04197.1 - 0.0019 16.9 0.8 0.34 9.5 0.1 2.3 2 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.17 OAJ04197.1 - 0.016 15.3 0.4 0.56 10.4 0.3 2.2 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 OAJ04197.1 - 0.079 12.2 0.1 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 OAJ04197.1 - 0.083 13.0 0.3 0.3 11.2 0.1 1.8 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 OAJ04197.1 - 0.098 11.8 0.0 0.16 11.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 OAJ04197.1 - 0.12 11.3 0.4 0.23 10.4 0.1 1.5 2 0 0 2 2 2 0 Septin Nic96 PF04097.9 OAJ04198.1 - 2.3e-161 538.0 0.0 3.1e-161 537.5 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Voltage_CLC PF00654.15 OAJ04199.1 - 1.8e-91 306.8 29.6 3.3e-91 305.9 20.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 OAJ04199.1 - 7.9e-13 47.9 0.1 2.4e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain RasGAP PF00616.14 OAJ04200.1 - 1.5e-28 99.8 0.0 3.3e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 OAJ04200.1 - 2.8e-12 46.7 0.0 1.6e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 OAJ04200.1 - 2.8e-05 24.0 0.4 0.0003 20.6 0.0 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal bZIP_1 PF00170.16 OAJ04201.1 - 1.5e-05 24.8 9.7 1.5e-05 24.8 6.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ04201.1 - 0.00047 19.9 7.3 0.001 18.8 5.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 OAJ04201.1 - 0.24 11.7 8.9 0.68 10.2 6.2 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor Thioredoxin PF00085.15 OAJ04202.1 - 9.7e-22 76.6 0.0 1.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ04202.1 - 9e-07 29.0 0.0 1.3e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ04202.1 - 4.4e-05 23.5 0.0 0.0014 18.7 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like KaiB PF07689.7 OAJ04202.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_7 PF13899.1 OAJ04202.1 - 0.0035 17.3 0.0 0.007 16.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 OAJ04202.1 - 0.0056 16.1 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 OAJ04202.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.1 OAJ04202.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF953 PF06110.6 OAJ04202.1 - 0.019 14.4 0.1 0.065 12.6 0.1 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Redoxin PF08534.5 OAJ04202.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.5 1 1 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 OAJ04202.1 - 0.025 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.6 OAJ04202.1 - 0.028 14.3 0.0 0.037 13.9 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF836 PF05768.9 OAJ04202.1 - 0.029 14.6 0.0 0.042 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DIM1 PF02966.11 OAJ04202.1 - 0.04 13.4 0.0 0.049 13.1 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 OAJ04202.1 - 0.062 12.8 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF2316 PF10078.4 OAJ04208.1 - 0.015 15.3 0.7 1.6 8.7 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) HemX PF04375.9 OAJ04208.1 - 0.038 12.5 0.1 0.049 12.2 0.1 1.3 1 0 0 1 1 1 0 HemX Mst1_SARAH PF11629.3 OAJ04208.1 - 0.12 12.1 1.0 0.76 9.6 0.1 2.3 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 PIF1 PF05970.9 OAJ04209.1 - 1.2e-21 77.1 0.1 8.3e-21 74.3 0.0 1.9 1 1 0 2 2 2 1 PIF1-like helicase Cyclin_N PF00134.18 OAJ04209.1 - 1.7e-13 50.2 0.0 4.6e-12 45.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain AAA_30 PF13604.1 OAJ04209.1 - 1.8e-13 50.5 0.5 5.2e-11 42.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain Helitron_like_N PF14214.1 OAJ04209.1 - 3.6e-10 39.8 0.2 1.2e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ04209.1 - 3.6e-07 29.8 1.3 1.3e-05 24.8 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain Cyclin_C PF02984.14 OAJ04209.1 - 1.6e-06 28.0 0.0 6.9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain AAA_16 PF13191.1 OAJ04209.1 - 0.026 14.4 4.0 0.069 13.1 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 OAJ04209.1 - 0.038 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ04209.1 - 0.27 10.9 0.8 1.9 8.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) CBFD_NFYB_HMF PF00808.18 OAJ04210.1 - 2.7e-14 52.9 0.0 4.5e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ04210.1 - 1.1e-05 25.3 0.0 1.9e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 OAJ04210.1 - 0.032 14.0 0.1 0.052 13.3 0.1 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region BUD22 PF09073.5 OAJ04210.1 - 3.8 6.4 5.6 0.44 9.5 0.4 1.8 2 0 0 2 2 2 0 BUD22 CM_2 PF01817.16 OAJ04211.1 - 3.2e-08 33.5 0.0 4e-06 26.8 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II 5-FTHF_cyc-lig PF01812.15 OAJ04212.1 - 2.3e-29 102.5 0.0 1.3e-27 96.7 0.0 2.1 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family RVT_2 PF07727.9 OAJ04213.1 - 8.4e-84 280.3 0.0 1.2e-83 279.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04213.1 - 2.6e-26 92.1 0.1 1.4e-25 89.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ04213.1 - 6.2e-07 28.9 0.1 1.3e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ04213.1 - 5.5e-05 22.6 0.0 0.00014 21.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 OAJ04213.1 - 0.00059 19.6 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ04213.1 - 0.034 13.6 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVP PF00077.15 OAJ04213.1 - 0.052 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.22 OAJ04213.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TEX19 PF15553.1 OAJ04215.1 - 4.1 7.2 6.2 8.4 6.2 4.3 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 CMS1 PF14617.1 OAJ04216.1 - 8.9e-17 60.9 14.6 6.8e-14 51.5 0.0 4.6 3 1 1 4 4 4 2 U3-containing 90S pre-ribosomal complex subunit DUF702 PF05142.7 OAJ04216.1 - 9 6.4 8.0 3.4 7.8 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) FAD_binding_4 PF01565.18 OAJ04217.1 - 8.1e-21 73.9 2.5 1.5e-20 73.1 1.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ04217.1 - 0.0039 17.0 0.1 0.0083 16.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DnaJ PF00226.26 OAJ04218.1 - 1.3e-11 44.0 0.0 2.8e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain SPT6_acidic PF14632.1 OAJ04218.1 - 0.13 12.4 7.0 0.21 11.7 4.8 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF1168 PF06658.7 OAJ04218.1 - 3.6 7.1 16.2 5.2 6.5 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Phage_integrase PF00589.17 OAJ04219.1 - 0.0052 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DnaJ PF00226.26 OAJ04221.1 - 1.9e-12 46.7 0.1 5.6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain RVT_1 PF00078.22 OAJ04224.1 - 0.0027 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ04224.1 - 0.054 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_fiber PF03335.8 OAJ04226.1 - 0.14 11.9 0.4 0.28 10.9 0.3 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat DnaJ PF00226.26 OAJ04227.1 - 2.5e-11 43.1 0.8 3.6e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain NdhM PF10664.4 OAJ04227.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Cyanobacterial and plastid NDH-1 subunit M SCA7 PF08313.7 OAJ04229.1 - 0.11 12.0 0.4 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 SCA7, zinc-binding domain Peptidase_S8 PF00082.17 OAJ04230.1 - 2.4e-41 141.7 0.0 7.9e-41 140.0 0.0 1.9 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ04230.1 - 2.7e-15 56.7 0.2 8.5e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ04230.1 - 0.00017 21.2 0.2 0.00047 19.8 0.1 1.8 1 0 0 1 1 1 1 PA domain CBM_17_28 PF03424.9 OAJ04230.1 - 0.0082 15.8 0.1 0.051 13.2 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain (family 17/28) DUF4232 PF14016.1 OAJ04230.1 - 0.02 14.5 1.4 0.041 13.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) DUF2404 PF10296.4 OAJ04231.1 - 0.0003 20.8 0.0 0.0006 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) COesterase PF00135.23 OAJ04233.1 - 1.2e-101 341.0 0.5 1.6e-101 340.6 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ04233.1 - 3.8e-07 29.9 0.3 0.0026 17.3 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold EcKinase PF02958.15 OAJ04234.1 - 6.4e-22 78.0 0.0 3.5e-12 46.0 0.0 2.3 2 1 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.6 OAJ04234.1 - 8.2e-09 34.5 0.0 1.5e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.18 OAJ04234.1 - 9.7e-07 28.7 0.1 7.2e-06 25.8 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DDE_Tnp_4 PF13359.1 OAJ04235.1 - 2.2e-22 79.3 0.0 7.2e-22 77.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 OAJ04235.1 - 0.00035 20.1 0.0 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Myb_DNA-bind_4 PF13837.1 OAJ04236.1 - 0.024 14.7 1.6 0.037 14.1 0.0 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pol_alpha_B_N PF08418.5 OAJ04238.1 - 0.8 9.1 5.1 0.96 8.9 3.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Rad60-SLD PF11976.3 OAJ04242.1 - 5.5e-13 48.3 0.6 1.3e-12 47.2 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 OAJ04242.1 - 0.00082 18.7 0.2 0.0021 17.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Phage_integrase PF00589.17 OAJ04249.1 - 6e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family WD40 PF00400.27 OAJ04250.1 - 3.6e-18 64.6 15.5 9.7e-10 37.9 1.6 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 OAJ04250.1 - 1.4e-07 31.3 0.0 0.0041 16.8 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 OAJ04250.1 - 0.00098 19.3 0.5 0.099 12.9 0.0 3.1 2 0 0 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.9 OAJ04250.1 - 0.019 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.11 OAJ04250.1 - 0.028 12.7 0.0 1 7.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain Mito_fiss_reg PF05308.6 OAJ04250.1 - 0.03 13.7 0.7 0.098 12.0 0.5 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator Sad1_UNC PF07738.8 OAJ04251.1 - 2.1e-22 79.3 0.0 8.8e-13 48.2 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal tRNA_m1G_MT PF01746.16 OAJ04253.1 - 5.2e-20 71.8 0.1 2.1e-16 60.0 0.0 3.4 3 1 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase PgaD PF13994.1 OAJ04253.1 - 0.01 15.3 0.6 0.023 14.1 0.4 1.6 1 0 0 1 1 1 0 PgaD-like protein GCV_H PF01597.14 OAJ04254.1 - 4.8e-42 142.4 0.3 5.8e-42 142.2 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 OAJ04254.1 - 9.9e-05 21.9 1.1 0.00019 21.0 0.3 1.9 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 OAJ04254.1 - 0.0012 18.5 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain zf-CSL PF05207.8 OAJ04255.1 - 5.4e-24 83.4 1.1 8.6e-24 82.8 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_5 PF13719.1 OAJ04255.1 - 0.0013 18.2 0.8 0.0022 17.5 0.6 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ04255.1 - 0.004 16.8 1.1 0.0071 16.0 0.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.5 OAJ04255.1 - 0.038 13.9 0.5 0.072 13.0 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_4 PF14570.1 OAJ04255.1 - 0.041 13.4 0.5 0.071 12.7 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 OAJ04256.1 - 8.2e-57 192.3 1.4 2.7e-55 187.3 1.0 2.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 OAJ04256.1 - 0.021 14.3 0.0 0.49 9.9 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Gag_p12 PF01141.13 OAJ04256.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.6 2 1 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DUF1768 PF08719.6 OAJ04257.1 - 9.5e-31 106.6 0.0 1.2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.6 OAJ04257.1 - 2.3e-05 23.9 0.0 6.8e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Bacteriophage protein GP30.3 SH3_1 PF00018.23 OAJ04258.1 - 2.5e-24 84.3 0.0 3.1e-11 42.4 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 OAJ04258.1 - 5.6e-15 54.6 0.0 2.4e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 OAJ04258.1 - 8.3e-14 50.8 0.0 1.1e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 OAJ04258.1 - 1.4e-10 40.9 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 OAJ04258.1 - 2.1e-05 24.0 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Abhydrolase_5 PF12695.2 OAJ04260.1 - 3.3e-24 85.2 0.0 6.6e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ04260.1 - 2e-17 63.8 1.8 2e-15 57.3 1.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 OAJ04260.1 - 6.7e-08 31.3 0.0 0.0023 16.4 0.0 3.3 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 OAJ04260.1 - 7.2e-08 32.2 0.0 0.011 15.3 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 OAJ04260.1 - 0.0001 21.8 0.2 0.0023 17.4 0.0 2.4 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 OAJ04260.1 - 0.0022 17.3 0.0 0.039 13.2 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 OAJ04260.1 - 0.0042 16.5 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 OAJ04260.1 - 0.0053 16.4 0.0 0.064 12.9 0.0 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 OAJ04260.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 OAJ04260.1 - 0.1 11.9 0.0 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase T2SM_b PF10741.4 OAJ04261.1 - 0.03 13.9 0.5 4.2 7.0 0.1 2.2 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Ribosomal_S5 PF00333.15 OAJ04262.1 - 2e-28 97.9 2.3 2.1e-28 97.8 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 OAJ04262.1 - 7.9e-22 76.3 0.1 1.3e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain zf-Apc11 PF12861.2 OAJ04263.1 - 1.2e-31 108.3 9.4 1.6e-31 108.0 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 OAJ04263.1 - 1.1e-26 92.6 9.0 1.5e-26 92.3 6.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ04263.1 - 1.8e-06 27.6 14.9 5.7e-06 26.0 10.3 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ04263.1 - 1.9e-05 24.2 11.8 7.4e-05 22.3 8.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ04263.1 - 0.0025 17.7 12.1 0.055 13.5 8.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 OAJ04263.1 - 0.4 10.7 9.9 0.15 12.0 4.9 1.8 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 OAJ04263.1 - 0.81 9.7 9.3 0.31 11.0 4.8 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.3 OAJ04263.1 - 1.1 8.8 6.5 1.8 8.1 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 OAJ04263.1 - 1.3 8.6 13.7 0.2 11.2 1.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 OAJ04263.1 - 2.5 8.1 10.3 12 6.0 7.2 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING_5 PF14634.1 OAJ04263.1 - 2.6 7.8 15.3 17 5.2 10.8 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 OAJ04263.1 - 4.3 7.5 11.4 2 8.6 6.0 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.3 OAJ04263.1 - 6.8 6.7 14.3 68 3.5 9.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain tRNA-synt_1c PF00749.16 OAJ04264.1 - 1.1e-101 339.7 0.0 2e-101 338.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 OAJ04264.1 - 3.3e-30 104.7 0.0 5.6e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 OAJ04264.1 - 4.5e-28 98.0 0.0 1.3e-27 96.5 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 OAJ04264.1 - 1.7e-08 35.0 8.5 1.7e-08 35.0 5.9 3.6 4 0 0 4 4 4 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 MoaC PF01967.16 OAJ04265.1 - 3e-38 130.5 1.1 2.5e-17 62.8 0.0 3.2 2 1 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 OAJ04265.1 - 2.2e-31 108.1 0.0 1.1e-30 105.9 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 OAJ04265.1 - 1.8e-25 89.9 0.0 3.2e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 OAJ04265.1 - 2e-06 27.9 0.0 3.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 OAJ04265.1 - 0.00014 21.8 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain HEM4 PF02602.10 OAJ04266.1 - 9.5e-16 57.7 0.9 1e-07 31.4 0.1 4.8 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD Whi5 PF08528.6 OAJ04267.1 - 0.0049 16.4 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Peptidase_S46 PF10459.4 OAJ04267.1 - 0.064 11.6 0.3 0.1 10.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase S46 TAFII28 PF04719.9 OAJ04268.1 - 7.4e-23 80.1 0.0 1.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 OAJ04268.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HrpA_pilin PF09589.5 OAJ04268.1 - 0.2 12.0 4.5 0.12 12.7 1.8 1.7 1 1 0 1 1 1 0 HrpA pilus formation protein GBP_C PF02841.9 OAJ04268.1 - 0.31 10.1 6.3 0.47 9.6 4.4 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Homeobox PF00046.24 OAJ04269.1 - 7.7e-19 67.0 1.5 1.3e-18 66.3 1.1 1.4 1 0 0 1 1 1 1 Homeobox domain Ras PF00071.17 OAJ04270.1 - 4.7e-65 217.8 0.0 5.6e-65 217.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ04270.1 - 1.5e-19 70.6 0.0 2.2e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ04270.1 - 2.3e-13 49.7 0.0 2.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ04270.1 - 2.9e-05 23.5 0.0 7.7e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ04270.1 - 3.9e-05 22.8 0.0 4.4e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ04270.1 - 0.00049 20.0 0.0 0.00074 19.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 OAJ04270.1 - 0.02 14.8 0.1 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 OAJ04270.1 - 0.027 13.6 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 OAJ04270.1 - 0.039 13.1 0.0 0.074 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ04270.1 - 0.041 13.4 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 OAJ04270.1 - 0.047 13.8 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ04270.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 OAJ04270.1 - 0.064 12.5 0.0 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 OAJ04270.1 - 0.079 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MCM PF00493.18 OAJ04270.1 - 0.12 11.1 0.0 0.36 9.5 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family Arrestin_C PF02752.17 OAJ04271.1 - 1e-14 54.7 0.0 3.8e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ04271.1 - 6.3e-08 32.5 0.0 4.6e-05 23.2 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Transposase_21 PF02992.9 OAJ04272.1 - 9.8e-23 80.4 0.0 1.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF1509 PF07420.6 OAJ04272.1 - 0.048 12.9 6.0 0.12 11.6 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Corona_nucleoca PF00937.13 OAJ04272.1 - 0.84 8.5 6.2 1.6 7.6 4.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Syja_N PF02383.13 OAJ04273.1 - 1.9e-89 299.5 0.0 2.5e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain U3_assoc_6 PF08640.6 OAJ04275.1 - 5e-12 45.4 0.6 5.6e-11 42.0 0.2 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 PTPA PF03095.10 OAJ04276.1 - 3.1e-88 295.8 0.0 5e-88 295.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TFIIF_alpha PF05793.7 OAJ04277.1 - 8.2 4.6 18.5 12 4.1 12.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BAR PF03114.13 OAJ04278.1 - 0.088 12.3 0.4 0.13 11.7 0.3 1.1 1 0 0 1 1 1 0 BAR domain zf-Tim10_DDP PF02953.10 OAJ04279.1 - 6.5e-19 66.9 4.0 6.5e-19 66.9 2.8 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 OAJ04279.1 - 0.085 11.8 0.1 0.085 11.8 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Ribosom_S12_S23 PF00164.20 OAJ04280.1 - 0.038 13.4 0.0 0.081 12.3 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12/S23 ABC_tran PF00005.22 OAJ04285.1 - 1.6e-33 115.8 0.0 4.4e-33 114.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ04285.1 - 4.7e-29 101.6 7.6 6.7e-29 101.1 5.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ04285.1 - 2.7e-07 30.8 0.0 0.0001 22.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ04285.1 - 0.0014 18.7 0.3 0.2 11.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 OAJ04285.1 - 0.0023 17.2 0.6 0.54 9.4 0.0 2.7 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ04285.1 - 0.0025 17.2 0.1 0.0063 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ04285.1 - 0.004 17.1 0.2 0.086 12.8 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 OAJ04285.1 - 0.0073 16.5 0.0 0.072 13.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 OAJ04285.1 - 0.019 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ04285.1 - 0.022 15.5 0.0 0.051 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 OAJ04285.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Histone PF00125.19 OAJ04287.1 - 2e-10 40.6 0.2 4.8e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ04287.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 OAJ04287.1 - 0.00065 19.8 0.7 0.0087 16.2 0.0 2.6 3 0 0 3 3 3 1 Kinetochore component CENP-S TAF PF02969.12 OAJ04287.1 - 0.001 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 OAJ04287.1 - 0.0049 16.1 0.1 0.0062 15.8 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T Clathrin PF00637.15 OAJ04287.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Region in Clathrin and VPS TFIID-31kDa PF02291.10 OAJ04287.1 - 0.039 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 OAJ04287.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated DUF975 PF06161.6 OAJ04288.1 - 0.26 10.9 7.4 0.019 14.6 0.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF975) DUF788 PF05620.6 OAJ04288.1 - 0.91 9.3 3.7 16 5.2 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF788) Virul_fac_BrkB PF03631.10 OAJ04288.1 - 1.1 8.5 9.6 0.58 9.4 3.6 2.4 1 1 1 2 2 2 0 Virulence factor BrkB DUF202 PF02656.10 OAJ04288.1 - 2.9 8.1 13.1 1.2 9.4 1.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DctQ PF04290.7 OAJ04288.1 - 6.9 6.4 11.8 8.3 6.1 0.5 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component CHRD PF07452.7 OAJ04289.1 - 1.9e-16 60.7 0.0 5.9e-07 30.1 0.0 2.8 2 2 0 2 2 2 2 CHRD domain GKAP PF03359.8 OAJ04290.1 - 0.16 11.5 4.9 0.29 10.6 3.4 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein PIF1 PF05970.9 OAJ04291.1 - 1.9e-21 76.4 0.0 3.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04291.1 - 7e-13 48.6 0.1 1.6e-11 44.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAJ04291.1 - 2.5e-07 30.6 0.0 6.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ04291.1 - 5.7e-07 29.2 0.4 1.7e-06 27.6 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain Helicase_RecD PF05127.9 OAJ04291.1 - 0.00073 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 OAJ04291.1 - 0.0018 18.2 0.3 0.02 14.8 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ04291.1 - 0.029 14.4 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Torsin PF06309.6 OAJ04291.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 OAJ04291.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ04291.1 - 0.19 11.1 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Bunya_RdRp PF04196.7 OAJ04291.1 - 0.65 7.9 0.0 0.99 7.3 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase DUF1664 PF07889.7 OAJ04292.1 - 0.0094 15.7 0.8 0.014 15.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) FUSC PF04632.7 OAJ04292.1 - 0.016 13.6 2.6 0.021 13.2 1.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Laminin_II PF06009.7 OAJ04292.1 - 0.026 14.3 0.3 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF724 PF05266.9 OAJ04292.1 - 0.041 13.5 0.8 0.052 13.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF883 PF05957.8 OAJ04292.1 - 0.12 12.7 4.0 0.11 12.9 0.6 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.4 OAJ04292.1 - 0.24 10.3 2.5 0.3 9.9 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 F-box-like PF12937.2 OAJ04293.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like Cellulase PF00150.13 OAJ04294.1 - 4e-12 45.9 0.2 5.8e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.17 OAJ04295.1 - 8.2e-49 166.2 11.5 1.4e-48 165.5 8.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 OAJ04295.1 - 5.5e-12 46.0 0.2 1.4e-11 44.7 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 AvrRpt-cleavage PF05627.6 OAJ04296.1 - 0.0036 16.3 0.7 0.008 15.2 0.5 1.5 1 0 0 1 1 1 1 Cleavage site for pathogenic type III effector avirulence factor Avr Mito_carr PF00153.22 OAJ04297.1 - 1.3e-47 159.4 0.3 9.1e-16 57.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_1 PF00018.23 OAJ04298.1 - 8.6e-40 133.9 7.1 1.4e-16 59.5 0.1 3.8 3 1 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 OAJ04298.1 - 2.5e-39 132.6 6.9 5.4e-14 51.4 0.2 3.5 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.7 OAJ04298.1 - 4.4e-28 96.7 0.0 9.2e-28 95.7 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 OAJ04298.1 - 1.7e-22 78.6 0.0 2.3e-09 36.5 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.6 OAJ04298.1 - 5.9e-06 26.3 1.7 0.085 13.0 0.1 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain API5 PF05918.6 OAJ04298.1 - 0.46 8.9 9.6 0.75 8.2 6.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) U79_P34 PF03064.11 OAJ04300.1 - 7.4 6.0 17.3 0.72 9.3 7.5 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Carn_acyltransf PF00755.15 OAJ04301.1 - 2.7e-128 428.6 0.0 5.6e-128 427.6 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase CDC45 PF02724.9 OAJ04302.1 - 6.9 4.5 4.8 15 3.4 3.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Spindle_Spc25 PF08234.7 OAJ04303.1 - 4.7e-14 52.1 0.0 1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 ERM PF00769.14 OAJ04303.1 - 0.00033 20.2 13.4 0.00057 19.4 9.3 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Cortex-I_coil PF09304.5 OAJ04303.1 - 0.0026 17.7 16.7 0.0056 16.7 11.6 1.5 1 0 0 1 1 1 1 Cortexillin I, coiled coil Macoilin PF09726.4 OAJ04303.1 - 0.011 14.0 7.9 0.014 13.7 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 OAJ04303.1 - 0.018 14.0 14.2 0.027 13.4 9.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 OAJ04303.1 - 0.15 11.9 12.3 0.3 10.9 8.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 OAJ04303.1 - 0.52 10.1 12.6 0.21 11.3 5.2 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 OAJ04303.1 - 0.59 8.4 5.7 0.84 7.9 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 OAJ04303.1 - 0.71 8.9 3.3 2.7 7.0 2.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 OAJ04303.1 - 1.6 7.7 13.0 2.6 6.9 9.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 OAJ04303.1 - 7.6 6.4 7.9 27 4.6 0.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PSI_PSAK PF01241.13 OAJ04304.1 - 0.035 14.1 0.7 0.09 12.8 0.5 1.7 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF605 PF04652.11 OAJ04304.1 - 9.2 5.5 11.8 15 4.8 8.2 1.2 1 0 0 1 1 1 0 Vta1 like Orbi_VP2 PF00898.12 OAJ04305.1 - 0.018 12.5 0.7 0.026 12.1 0.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Myb_DNA-bind_4 PF13837.1 OAJ04305.1 - 0.022 14.8 1.6 0.022 14.8 1.1 3.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3298 PF11738.3 OAJ04305.1 - 1.9 9.0 6.1 1.6e+02 2.9 2.0 4.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3298) Yippee-Mis18 PF03226.9 OAJ04309.1 - 8e-20 70.6 0.2 8.9e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly UPF0047 PF01894.12 OAJ04310.1 - 5.4e-41 139.1 0.0 6.8e-41 138.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TauD PF02668.11 OAJ04311.1 - 2.9e-46 158.2 1.8 3.6e-46 157.9 1.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ORMDL PF04061.9 OAJ04312.1 - 1.4e-52 176.8 4.1 1.8e-52 176.5 2.8 1.1 1 0 0 1 1 1 1 ORMDL family Pex14_N PF04695.8 OAJ04312.1 - 1.9 8.5 7.4 3.4 7.7 5.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 OAJ04313.1 - 0.00071 19.0 3.4 0.0022 17.4 0.4 2.1 2 0 0 2 2 2 1 Mitochondrial fission regulator RskA PF10099.4 OAJ04313.1 - 0.00093 18.9 11.8 0.35 10.5 0.4 3.2 3 0 0 3 3 3 3 Anti-sigma-K factor rskA Glyco_hydro_3_C PF01915.17 OAJ04313.1 - 0.012 15.1 0.3 0.026 14.0 0.0 1.7 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Pkinase PF00069.20 OAJ04314.1 - 5.8e-56 189.5 0.0 3.6e-55 186.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04314.1 - 1.8e-27 96.0 0.0 2.9e-18 65.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04314.1 - 0.0001 21.4 0.1 0.043 12.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Myc-LZ PF02344.10 OAJ04314.1 - 0.0029 17.1 2.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Myc leucine zipper domain APH PF01636.18 OAJ04314.1 - 0.025 14.3 0.5 0.53 9.9 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_C PF00433.19 OAJ04314.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.7 3 0 0 3 3 3 0 Protein kinase C terminal domain TMEM154 PF15102.1 OAJ04316.1 - 0.00089 18.9 0.1 0.007 16.0 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family WD40 PF00400.27 OAJ04317.1 - 2.4e-19 68.3 10.4 5.1e-10 38.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.20 OAJ04317.1 - 9.1e-16 57.7 0.0 1.3e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04317.1 - 4.9e-08 32.3 0.0 0.00044 19.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.17 OAJ04317.1 - 3e-07 29.9 12.5 0.019 15.0 0.5 6.7 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 OAJ04317.1 - 0.0003 21.0 1.5 0.68 10.2 0.1 3.5 2 1 0 2 2 2 2 HEAT repeats Nucleoporin_N PF08801.6 OAJ04317.1 - 0.016 13.9 1.5 0.29 9.8 0.3 2.9 2 2 2 4 4 4 0 Nup133 N terminal like RED_C PF07807.6 OAJ04317.1 - 0.26 11.4 0.0 0.68 10.1 0.0 1.6 1 0 0 1 1 1 0 RED-like protein C-terminal region Cohesin_HEAT PF12765.2 OAJ04317.1 - 0.26 11.2 2.5 0.27 11.2 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 OAJ04317.1 - 0.53 8.5 1.1 1.3 7.2 0.3 1.8 2 0 0 2 2 2 0 Adaptin N terminal region Patched PF02460.13 OAJ04318.1 - 6.5e-64 216.2 6.1 3.4e-39 134.4 0.2 2.7 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 OAJ04318.1 - 1.8e-43 147.6 13.2 1.6e-23 82.8 0.2 3.3 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 OAJ04318.1 - 0.0004 17.9 1.3 0.00058 17.4 0.9 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Vps51 PF08700.6 OAJ04319.1 - 1.3e-22 79.3 0.0 1.9e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 OAJ04319.1 - 8e-06 24.5 0.2 9.6e-06 24.2 0.2 1.0 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 OAJ04319.1 - 0.00071 19.5 0.3 0.001 19.0 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Vps52 PF04129.7 OAJ04319.1 - 0.018 13.5 0.1 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF3086 PF11285.3 OAJ04319.1 - 0.019 13.8 0.1 0.025 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) FlgN PF05130.7 OAJ04319.1 - 0.066 13.4 0.4 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 FlgN protein HTH_29 PF13551.1 OAJ04321.1 - 0.052 13.7 1.6 0.088 12.9 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn helix DcpS_C PF11969.3 OAJ04328.1 - 7.8e-29 100.2 0.2 1.6e-28 99.2 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 OAJ04328.1 - 1.7e-23 83.0 0.0 5.2e-23 81.5 0.0 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 OAJ04328.1 - 0.068 13.7 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 HIT domain Ribonuc_red_lgC PF02867.10 OAJ04329.1 - 8.2e-212 704.5 0.0 1e-211 704.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 OAJ04329.1 - 7e-24 83.4 0.0 1.7e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 OAJ04329.1 - 9.6e-18 64.4 0.4 3.1e-17 62.7 0.3 2.0 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 OAJ04329.1 - 0.0046 15.1 0.0 0.007 14.4 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase IPK PF03770.11 OAJ04330.1 - 3.1e-38 131.3 0.0 8.4e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase MARVEL PF01284.18 OAJ04331.1 - 7.1e-12 45.3 12.3 1e-11 44.8 8.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain LIM PF00412.17 OAJ04332.1 - 8.8e-33 112.1 25.4 8.3e-14 51.4 4.2 5.5 5 0 0 5 5 5 5 LIM domain ILVD_EDD PF00920.16 OAJ04333.1 - 1.8e-195 650.3 0.1 2.1e-195 650.0 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Chitin_synth_1 PF01644.12 OAJ04335.1 - 4.5e-32 111.0 0.0 4.8e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.10 OAJ04335.1 - 1.1e-11 43.9 0.0 3.9e-06 25.5 0.0 3.2 2 1 1 3 3 3 3 Chitin synthase Chitin_synth_1N PF08407.6 OAJ04335.1 - 2.5e-09 36.7 0.4 6.9e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal DUF3482 PF11981.3 OAJ04335.1 - 7.3 5.7 5.4 12 4.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Mito_carr PF00153.22 OAJ04336.1 - 2.1e-64 213.2 5.1 1.7e-23 82.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sorb PF02208.11 OAJ04336.1 - 0.15 11.4 0.4 0.31 10.4 0.3 1.5 1 0 0 1 1 1 0 Sorbin homologous domain SSrecog PF03531.9 OAJ04337.1 - 2.3e-73 246.1 0.1 6.3e-72 241.5 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 OAJ04337.1 - 2e-22 78.9 0.1 5.9e-22 77.4 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.9 OAJ04337.1 - 0.00031 18.9 2.0 0.00043 18.4 1.4 1.2 1 0 0 1 1 1 1 CDC45-like protein NMO PF03060.10 OAJ04338.1 - 9.7e-71 238.6 4.0 1.1e-70 238.3 2.8 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 OAJ04338.1 - 3.3e-05 22.9 1.8 6.7e-05 21.8 1.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 OAJ04338.1 - 7.1e-05 21.8 3.3 0.0002 20.3 2.3 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.10 OAJ04338.1 - 0.022 14.4 0.0 0.071 12.7 0.0 1.9 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DHO_dh PF01180.16 OAJ04338.1 - 0.078 11.9 1.3 0.12 11.2 0.9 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Sugar_tr PF00083.19 OAJ04339.1 - 3.4e-120 401.6 23.4 3.9e-120 401.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ04339.1 - 6.4e-22 77.7 37.6 8.2e-21 74.1 8.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MPC PF03650.8 OAJ04340.1 - 8.9e-38 128.9 0.1 9.6e-38 128.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3318 PF11780.3 OAJ04340.1 - 0.13 11.7 2.2 0.18 11.3 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3318) Snf7 PF03357.16 OAJ04341.1 - 5.9e-30 103.8 17.9 5.9e-30 103.8 12.4 1.5 1 1 0 1 1 1 1 Snf7 HAD_2 PF13419.1 OAJ04343.1 - 1.5e-16 61.0 0.0 1.6e-12 48.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ04343.1 - 2.8e-08 34.4 0.0 6.1e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 OAJ04343.1 - 0.057 12.9 0.0 8.9 5.7 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase_6 PF13344.1 OAJ04343.1 - 0.1 12.5 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ04343.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase FH2 PF02181.18 OAJ04344.1 - 1.6e-82 277.3 0.0 2e-82 277.0 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Cyanate_lyase PF02560.9 OAJ04345.1 - 9.8e-35 117.9 0.0 1.4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 OAJ04345.1 - 0.00034 20.7 0.0 0.0005 20.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 OAJ04345.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_3 PF01381.17 OAJ04345.1 - 0.024 14.4 0.1 0.093 12.5 0.1 1.9 1 1 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.2 OAJ04345.1 - 0.052 13.6 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain KorB PF08535.5 OAJ04345.1 - 0.087 12.9 0.0 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 KorB domain HTH_38 PF13936.1 OAJ04345.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sugar_tr PF00083.19 OAJ04346.1 - 7.3e-128 426.9 20.5 8.3e-128 426.7 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ04346.1 - 8.2e-22 77.3 36.8 7.4e-19 67.6 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.4 OAJ04346.1 - 2.7 7.9 7.0 0.46 10.4 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) FAA_hydrolase PF01557.13 OAJ04348.1 - 5.9e-54 182.8 0.0 7.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tim17 PF02466.14 OAJ04349.1 - 5.3e-15 55.6 11.3 8.1e-15 54.9 7.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_45 PF02015.11 OAJ04350.1 - 4.4e-48 164.0 6.1 4.4e-48 164.0 4.3 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 45 SelP_N PF04592.9 OAJ04350.1 - 0.0035 16.7 8.8 0.0048 16.3 6.1 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region Zip PF02535.17 OAJ04350.1 - 0.11 11.4 13.2 0.16 10.9 9.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_45 PF02015.11 OAJ04351.1 - 5.2e-47 160.5 9.6 5.8e-47 160.3 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 GTP_EFTU PF00009.22 OAJ04352.1 - 1.6e-56 190.7 0.0 2.6e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ04352.1 - 3e-36 123.5 0.5 6.2e-36 122.5 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ04352.1 - 2.1e-16 59.7 1.2 2.1e-16 59.7 0.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 OAJ04352.1 - 0.00059 19.4 0.5 0.0018 17.8 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 OAJ04352.1 - 0.0013 18.6 0.3 0.004 17.0 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FlpD PF02662.11 OAJ04352.1 - 0.043 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit AAA_29 PF13555.1 OAJ04352.1 - 0.098 12.1 0.3 4.6 6.8 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain WD40 PF00400.27 OAJ04353.1 - 5.3e-16 57.8 0.1 9.1e-06 25.3 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ04353.1 - 0.02 15.1 0.7 0.12 12.6 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Abhydrolase_6 PF12697.2 OAJ04354.1 - 2.4e-22 79.9 0.0 3.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ04354.1 - 1.3e-09 38.0 0.0 3.7e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ04354.1 - 3e-06 26.9 0.0 1.1e-05 25.1 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLIC PF05783.6 OAJ04355.1 - 3e-43 148.2 4.4 9.7e-26 90.4 0.0 6.8 6 1 1 7 7 7 4 Dynein light intermediate chain (DLIC) MCM PF00493.18 OAJ04355.1 - 8e-05 21.5 0.0 0.00017 20.5 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 OAJ04355.1 - 0.0005 20.1 0.2 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 OAJ04355.1 - 0.0015 17.9 0.1 0.7 9.2 0.0 2.9 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 OAJ04355.1 - 0.018 14.9 0.1 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 OAJ04355.1 - 0.022 14.1 0.0 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ04355.1 - 0.026 15.0 0.1 0.44 11.0 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 OAJ04355.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ04355.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 OAJ04355.1 - 0.078 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 OAJ04355.1 - 0.083 13.0 0.1 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ04355.1 - 0.1 13.4 0.1 0.34 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ04355.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.1 OAJ04356.1 - 2.9e-26 91.1 0.0 7.1e-07 29.1 0.0 8.8 8 1 2 10 10 10 4 PPR repeat family PPR_3 PF13812.1 OAJ04356.1 - 2e-23 80.6 23.1 0.019 15.1 0.0 14.1 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 OAJ04356.1 - 6.8e-20 69.5 5.9 0.0041 17.0 0.0 9.6 10 0 0 10 10 10 5 PPR repeat PPR_1 PF12854.2 OAJ04356.1 - 6.1e-12 44.8 0.2 0.47 9.9 0.0 7.5 8 0 0 8 8 8 4 PPR repeat TPR_19 PF14559.1 OAJ04356.1 - 0.016 15.5 0.8 0.92 9.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04356.1 - 0.035 14.7 0.1 0.035 14.7 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04356.1 - 0.094 12.6 3.1 3.1 7.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ04356.1 - 0.22 12.2 0.1 0.22 12.2 0.1 8.1 10 0 0 10 10 10 0 Tetratricopeptide repeat RNA_pol_I_A49 PF06870.7 OAJ04357.1 - 1.2e-71 241.4 0.0 1.6e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DnaJ PF00226.26 OAJ04359.1 - 1.1e-21 76.3 0.1 4e-21 74.5 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 OAJ04359.1 - 0.078 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Hpt PF01627.18 OAJ04360.1 - 7.2e-10 38.7 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Hpt domain Methyltransf_23 PF13489.1 OAJ04362.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ04362.1 - 3.9e-09 36.8 0.0 7.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ04362.1 - 1.6e-08 34.9 0.0 2.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ04362.1 - 0.00013 22.5 0.0 0.00021 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ04362.1 - 0.00016 21.3 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 OAJ04362.1 - 0.00033 19.4 0.0 0.00043 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 OAJ04362.1 - 0.073 12.5 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PMI_typeI PF01238.16 OAJ04363.1 - 1.7e-110 369.5 0.0 4.8e-110 368.0 0.0 1.6 1 1 0 1 1 1 1 Phosphomannose isomerase type I UBN2 PF14223.1 OAJ04364.1 - 1.1e-06 28.4 0.1 2e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ04364.1 - 5.7e-05 22.6 0.0 9.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.12 OAJ04364.1 - 0.021 14.8 0.1 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_2 PF07727.9 OAJ04365.1 - 2.2e-82 275.7 0.0 3.3e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04365.1 - 1.9e-23 82.8 0.2 6.9e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ04365.1 - 8.5e-06 25.3 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ04365.1 - 0.044 13.3 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 OAJ04365.1 - 0.21 10.9 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) tRNA-synt_1 PF00133.17 OAJ04366.1 - 3.6e-211 702.2 0.0 2.9e-210 699.3 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ04366.1 - 4.4e-38 130.4 0.4 9e-38 129.4 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ04366.1 - 9e-20 70.6 0.6 1e-09 37.5 0.1 4.7 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAJ04366.1 - 2.4e-10 40.0 0.5 2.3e-06 27.0 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 OAJ04366.1 - 0.00024 21.0 3.0 0.00024 21.0 2.1 2.5 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 OAJ04366.1 - 0.00029 20.0 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 OAJ04366.1 - 0.00087 18.2 0.0 0.034 12.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (R) Scm3 PF10384.4 OAJ04373.1 - 1.2e-06 27.9 2.2 1.3e-06 27.8 0.3 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 2OG-FeII_Oxy_3 PF13640.1 OAJ04374.1 - 3.7e-09 37.0 0.0 6.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ04374.1 - 4.7e-07 29.3 0.1 9.5e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.6 OAJ04374.1 - 0.039 13.7 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein L27 PF02828.11 OAJ04374.1 - 0.052 13.2 0.0 0.69 9.6 0.0 2.5 2 0 0 2 2 2 0 L27 domain ADH_N PF08240.7 OAJ04375.1 - 3.8e-28 97.4 0.8 7.8e-28 96.4 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 OAJ04375.1 - 7.3e-07 28.7 3.1 7.3e-07 28.7 2.2 2.6 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 OAJ04375.1 - 0.00041 19.8 0.0 0.051 13.1 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase RRM_1 PF00076.17 OAJ04376.1 - 5.6e-10 38.7 0.0 2.6e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04376.1 - 6.3e-10 38.8 0.0 1.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04376.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tubulin PF00091.20 OAJ04377.1 - 5.8e-64 215.8 0.0 8.8e-64 215.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ04377.1 - 3e-40 137.1 0.0 4.3e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ04377.1 - 4.7e-05 23.4 0.0 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ04377.1 - 0.0021 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.1 OAJ04377.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DUF2874 PF11396.3 OAJ04378.1 - 0.039 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) TRAM_LAG1_CLN8 PF03798.11 OAJ04379.1 - 1.3e-38 132.5 20.9 1.9e-38 132.0 14.5 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 OAJ04379.1 - 0.094 12.2 2.4 0.12 11.9 0.0 2.3 2 0 0 2 2 2 0 TRAM1-like protein ABC_membrane PF00664.18 OAJ04381.1 - 6.3e-58 196.3 23.6 3.4e-31 108.6 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ04381.1 - 8.4e-54 181.5 0.2 1.9e-30 105.9 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 OAJ04381.1 - 5.6e-11 42.9 0.0 0.011 15.7 0.0 4.4 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 OAJ04381.1 - 6.3e-08 32.1 3.9 0.002 17.3 0.1 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ04381.1 - 6.4e-07 28.9 0.4 0.053 12.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ04381.1 - 1.1e-06 28.1 0.3 0.0014 18.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ04381.1 - 2.3e-06 27.7 7.0 0.016 15.1 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain Miro PF08477.8 OAJ04381.1 - 5.3e-06 26.9 1.2 0.03 14.8 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 OAJ04381.1 - 7.6e-06 25.8 0.7 0.0059 16.5 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 OAJ04381.1 - 4.1e-05 22.6 0.0 0.0076 15.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 OAJ04381.1 - 6.7e-05 22.1 0.2 0.32 10.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ04381.1 - 0.00016 22.4 0.2 0.27 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 OAJ04381.1 - 0.00035 20.4 0.6 0.0016 18.3 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 OAJ04381.1 - 0.00048 19.6 0.1 0.15 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 OAJ04381.1 - 0.00051 19.8 0.5 0.19 11.3 0.0 3.6 4 0 0 4 4 3 1 Archaeal ATPase AAA_14 PF13173.1 OAJ04381.1 - 0.00099 19.0 0.8 14 5.6 0.0 4.1 4 0 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 OAJ04381.1 - 0.0012 18.6 3.5 0.082 12.7 0.0 3.2 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.7 OAJ04381.1 - 0.0013 17.8 0.6 0.47 9.5 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 OAJ04381.1 - 0.0019 18.3 1.2 2.1 8.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 OAJ04381.1 - 0.0096 16.2 1.6 0.96 9.7 0.1 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ04381.1 - 0.0099 15.5 1.9 3.1 7.4 0.1 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 OAJ04381.1 - 0.01 15.5 3.7 0.33 10.6 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ04381.1 - 0.016 14.6 0.4 0.056 12.9 0.0 2.0 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 OAJ04381.1 - 0.02 15.2 17.3 0.17 12.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.1 OAJ04381.1 - 0.023 14.5 0.5 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ04381.1 - 0.028 13.0 0.3 0.61 8.6 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 OAJ04381.1 - 0.032 14.4 0.1 14 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 OAJ04381.1 - 0.045 13.2 2.2 1.9 7.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 OAJ04381.1 - 0.06 12.8 0.4 6.3 6.2 0.3 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 OAJ04381.1 - 0.087 11.6 0.7 5.6 5.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 OAJ04381.1 - 0.13 11.9 1.3 5.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 OAJ04381.1 - 0.17 12.0 0.8 29 4.8 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 OAJ04381.1 - 0.23 10.0 0.1 8.9 4.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 OAJ04381.1 - 0.5 9.8 1.6 18 4.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 OAJ04381.1 - 1.4 8.4 2.7 6.5 6.2 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein DIM PF08194.7 OAJ04381.1 - 1.4 8.8 4.1 0.87 9.5 0.2 2.7 2 0 0 2 2 1 0 DIM protein DUF1014 PF06244.7 OAJ04382.1 - 2.6e-20 72.8 23.4 8.6e-19 67.9 16.2 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4551 PF15087.1 OAJ04382.1 - 2.1 6.6 9.8 2.5 6.3 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HTH_WhiA PF02650.9 OAJ04382.1 - 7.7 6.9 10.4 2.4 8.6 0.0 3.2 2 2 1 3 3 3 0 WhiA C-terminal HTH domain An_peroxidase PF03098.10 OAJ04383.1 - 1.2e-70 238.4 0.0 1.6e-68 231.4 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ04383.1 - 2.2e-14 52.8 0.0 3.4e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Actin PF00022.14 OAJ04384.1 - 5.3e-117 390.5 0.0 6.4e-117 390.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 OAJ04384.1 - 0.076 11.5 0.0 0.7 8.4 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Cript PF10235.4 OAJ04385.1 - 1.9e-24 85.8 1.3 1.9e-24 85.8 0.9 1.6 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT C6_DPF PF10170.4 OAJ04385.1 - 0.024 14.6 5.4 0.052 13.6 2.1 2.1 2 1 0 2 2 2 0 Cysteine-rich domain zinc_ribbon_2 PF13240.1 OAJ04385.1 - 0.053 13.0 1.7 0.053 13.0 1.2 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Herpes_capsid PF06112.6 OAJ04385.1 - 0.095 12.7 5.2 0.1 12.6 3.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-ribbon_3 PF13248.1 OAJ04385.1 - 0.4 9.9 12.2 0.1 11.8 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DUF2039 PF10217.4 OAJ04385.1 - 0.41 10.6 13.3 0.11 12.4 5.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 OAJ04385.1 - 2.8 7.8 13.8 36 4.2 8.0 2.8 2 1 1 3 3 3 0 Double zinc ribbon Bax1-I PF01027.15 OAJ04386.1 - 3.5e-35 121.4 7.8 7.3e-35 120.4 5.4 1.5 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 2OG-FeII_Oxy_2 PF13532.1 OAJ04387.1 - 1.5e-26 93.4 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ04387.1 - 0.0039 17.4 0.0 0.024 14.9 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RINGv PF12906.2 OAJ04389.1 - 1.8e-13 50.2 15.5 3.4e-13 49.4 10.8 1.5 1 0 0 1 1 1 1 RING-variant domain DUF2256 PF10013.4 OAJ04389.1 - 0.037 13.7 0.1 0.037 13.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF948 PF06103.6 OAJ04389.1 - 0.23 11.3 0.6 0.63 9.9 0.3 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2681 PF10883.3 OAJ04389.1 - 0.63 10.2 3.6 3 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) V_ATPase_I PF01496.14 OAJ04389.1 - 8.6 4.0 8.8 19 2.9 6.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AdoHcyase PF05221.12 OAJ04390.1 - 2.6e-138 459.3 0.1 3e-138 459.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 OAJ04390.1 - 8.4e-84 279.3 2.0 1.3e-83 278.7 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 OAJ04390.1 - 1e-08 34.5 0.3 2.2e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 OAJ04390.1 - 0.00051 19.4 0.1 0.00084 18.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 OAJ04390.1 - 0.0027 17.6 0.0 0.0065 16.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DUF4448 PF14610.1 OAJ04390.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) NAD_binding_7 PF13241.1 OAJ04390.1 - 0.096 12.9 0.2 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding WD40 PF00400.27 OAJ04391.1 - 6.2e-20 70.2 0.8 1.7e-05 24.5 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 OAJ04391.1 - 1.6e-05 24.9 1.8 0.062 13.6 0.0 4.9 5 1 0 5 5 5 2 PQQ-like domain dCMP_cyt_deam_1 PF00383.17 OAJ04392.1 - 1.7e-06 27.5 0.0 3.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region F_actin_cap_B PF01115.12 OAJ04393.1 - 7.2e-84 280.7 0.0 8.4e-84 280.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF829 PF05705.9 OAJ04393.1 - 0.036 13.7 0.0 0.086 12.5 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Nup84_Nup100 PF04121.8 OAJ04394.1 - 6.9e-84 281.8 0.0 9.9e-38 129.2 0.0 4.5 4 1 0 4 4 4 4 Nuclear pore protein 84 / 107 Aida_N PF08910.5 OAJ04394.1 - 0.064 13.4 0.1 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Aida N-terminus ThiF PF00899.16 OAJ04395.1 - 2.2e-08 33.9 0.0 4.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family PT PF04886.7 OAJ04395.1 - 1.2 8.5 9.4 0.21 10.9 1.6 2.7 2 0 0 2 2 2 0 PT repeat ThiF PF00899.16 OAJ04396.1 - 1.7e-32 112.0 0.0 2.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 OAJ04396.1 - 0.0064 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.14 OAJ04397.1 - 5.6e-39 131.8 3.2 2.7e-22 78.3 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 OAJ04397.1 - 7.6e-13 47.5 1.9 1.3e-12 46.7 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 OAJ04397.1 - 0.0021 17.9 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Cyclin_N PF00134.18 OAJ04397.1 - 0.047 13.2 0.6 0.23 11.0 0.1 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.9 OAJ04398.1 - 6.4e-25 86.3 0.4 1.1e-24 85.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 OAJ04398.1 - 5.8e-20 71.2 0.3 9.4e-20 70.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Clat_adaptor_s PF01217.15 OAJ04399.1 - 2.2e-19 69.5 0.0 3.3e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Dendrin PF15498.1 OAJ04399.1 - 0.17 10.3 0.0 0.17 10.3 0.0 1.3 2 0 0 2 2 2 0 Nephrin and CD2AP-binding protein, Dendrin RhoGEF PF00621.15 OAJ04400.1 - 8.2e-41 139.8 0.0 1.3e-40 139.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 OAJ04400.1 - 2.5e-12 46.0 0.2 2.7e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ04400.1 - 6.8e-10 38.5 0.3 2.3e-05 24.0 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ04400.1 - 9.6e-07 28.0 0.8 1.5 9.1 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 OAJ04400.1 - 6.5e-05 22.5 0.2 7.8 7.1 0.0 4.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 OAJ04400.1 - 0.0069 16.3 0.0 0.53 10.5 0.0 2.9 2 0 0 2 2 2 1 Leucine Rich repeat GATase_4 PF13230.1 OAJ04401.1 - 1.7e-18 66.3 0.0 4.7e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ04401.1 - 1e-09 38.4 0.0 4.3e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 OAJ04401.1 - 5.5e-08 31.9 0.1 5.9e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF1454 PF07305.7 OAJ04401.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) COesterase PF00135.23 OAJ04402.1 - 2.8e-78 263.9 0.3 7e-70 236.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ04402.1 - 0.00013 21.5 0.0 0.00094 18.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ESX-1_EspG PF14011.1 OAJ04402.1 - 0.12 11.6 1.0 2.5 7.2 0.2 2.3 2 0 0 2 2 2 0 EspG family PP-binding PF00550.20 OAJ04403.1 - 5.7e-15 55.3 0.3 7.8e-15 54.8 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 OAJ04403.1 - 2.8e-07 30.4 0.2 4.4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 OAJ04403.1 - 0.042 13.9 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) KH_1 PF00013.24 OAJ04404.1 - 5e-06 26.0 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAJ04404.1 - 4e-05 23.1 0.0 9.9e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 OAJ04404.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 KH domain Ribosomal_L17 PF01196.14 OAJ04406.1 - 3.4e-26 91.6 0.0 1.1e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 Band_7 PF01145.20 OAJ04408.1 - 1.2e-20 74.1 0.6 1.2e-20 74.1 0.4 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family AAA_25 PF13481.1 OAJ04409.1 - 0.0069 15.8 0.1 0.057 12.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.10 OAJ04409.1 - 0.014 14.2 0.0 0.043 12.7 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_19 PF13245.1 OAJ04409.1 - 0.048 13.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 OAJ04409.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 OAJ04409.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 OAJ04410.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 OAJ04410.1 - 0.00039 21.2 0.1 0.0018 19.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ04410.1 - 0.00076 19.3 0.2 0.0055 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ04410.1 - 0.003 17.8 0.0 0.0082 16.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 OAJ04410.1 - 0.004 15.9 0.0 0.0061 15.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 OAJ04410.1 - 0.041 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ04410.1 - 0.042 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 OAJ04410.1 - 0.049 12.7 0.0 0.1 11.6 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.5 OAJ04410.1 - 0.06 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 OAJ04410.1 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GFA PF04828.9 OAJ04415.1 - 4.1e-09 36.2 1.3 3.1e-05 23.8 0.1 3.0 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Ank PF00023.25 OAJ04417.1 - 1.6e-32 109.6 0.0 4.7e-07 29.3 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 OAJ04417.1 - 4.8e-32 109.2 0.1 5.5e-11 42.3 0.0 5.0 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ04417.1 - 2.6e-30 104.6 0.0 3.1e-21 75.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ04417.1 - 3e-27 94.4 0.3 6.4e-11 42.4 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ04417.1 - 1.3e-21 74.4 0.7 8.3e-05 22.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.16 OAJ04417.1 - 7.9e-18 64.1 8.8 7.9e-18 64.1 6.1 2.8 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 OAJ04417.1 - 1.5e-10 40.6 3.0 1.5e-10 40.6 2.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ04417.1 - 0.00044 20.2 4.4 0.00044 20.2 3.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ04417.1 - 0.0094 16.0 1.6 0.0094 16.0 1.1 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 OAJ04417.1 - 0.11 12.2 3.4 0.16 11.6 1.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger FYVE_2 PF02318.11 OAJ04417.1 - 0.25 11.2 7.3 0.065 13.1 1.6 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger CMS1 PF14617.1 OAJ04417.1 - 0.28 10.2 0.1 1.2 8.1 0.0 2.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SAPS PF04499.10 OAJ04418.1 - 0.0099 14.5 6.6 0.014 14.0 4.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Raftlin PF15250.1 OAJ04418.1 - 0.36 9.3 10.2 0.54 8.7 7.0 1.2 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.5 OAJ04418.1 - 0.41 9.6 23.0 0.82 8.6 15.9 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ04418.1 - 0.54 8.1 24.8 0.73 7.6 17.2 1.1 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 OAJ04418.1 - 0.9 8.9 20.4 1.5 8.2 14.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Na_trans_assoc PF06512.8 OAJ04418.1 - 1.1 9.1 16.3 2 8.3 11.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Vfa1 PF08432.5 OAJ04418.1 - 1.3 8.9 17.0 2.2 8.2 11.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPP4R2 PF09184.6 OAJ04418.1 - 1.6 8.2 21.3 3.3 7.1 14.8 1.5 1 0 0 1 1 1 0 PPP4R2 TEX19 PF15553.1 OAJ04418.1 - 2 8.2 12.0 46 3.8 9.3 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 Paf1 PF03985.8 OAJ04418.1 - 2.8 6.5 22.9 3.8 6.1 15.8 1.1 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 OAJ04418.1 - 3.2 7.0 26.7 5.1 6.4 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ebola_NP PF05505.7 OAJ04418.1 - 5.4 4.9 18.3 8.1 4.3 12.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4407 PF14362.1 OAJ04418.1 - 6.5 5.6 5.5 9.2 5.1 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ycf1 PF05758.7 OAJ04418.1 - 9.2 3.8 14.9 12 3.4 10.3 1.1 1 0 0 1 1 1 0 Ycf1 Thioredoxin PF00085.15 OAJ04419.1 - 2.8e-36 123.3 0.0 4.3e-25 87.3 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 OAJ04419.1 - 5.7e-15 55.5 0.0 0.00015 21.6 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 OAJ04419.1 - 5.1e-06 26.6 0.8 0.0005 20.2 0.1 3.4 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 OAJ04419.1 - 2.3e-05 24.1 0.1 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_8 PF13905.1 OAJ04419.1 - 0.00011 22.2 0.1 0.002 18.2 0.0 2.7 3 0 0 3 3 2 1 Thioredoxin-like AhpC-TSA PF00578.16 OAJ04419.1 - 0.001 18.7 0.2 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family DeoC PF01791.4 OAJ04419.1 - 0.0015 17.8 0.0 0.0038 16.5 0.0 1.6 2 0 0 2 2 2 1 DeoC/LacD family aldolase Redoxin PF08534.5 OAJ04419.1 - 0.0091 15.5 0.1 0.027 14.0 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 OAJ04419.1 - 0.011 15.6 0.0 0.053 13.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.1 OAJ04419.1 - 0.027 14.0 0.2 0.069 12.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin DUF2360 PF10152.4 OAJ04419.1 - 2.4 8.4 5.1 5 7.3 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DEC-1_N PF04625.8 OAJ04419.1 - 7.7 5.0 15.9 12 4.3 11.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OPT PF03169.10 OAJ04421.1 - 1.4e-157 525.8 34.9 1.6e-157 525.6 24.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SAS4 PF15460.1 OAJ04422.1 - 0.034 14.0 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 RVT_1 PF00078.22 OAJ04426.1 - 7.1e-28 97.4 0.0 1.2e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 OAJ04426.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase NDUFB10 PF10249.4 OAJ04427.1 - 0.014 15.5 0.3 0.016 15.3 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HAD_2 PF13419.1 OAJ04427.1 - 0.1 12.8 0.1 0.11 12.6 0.0 1.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DPBB_1 PF03330.13 OAJ04428.1 - 3.4e-05 23.7 0.0 6.1e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ04428.1 - 0.00069 19.2 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Barwin family GCV_T_C PF08669.6 OAJ04428.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain RVT_3 PF13456.1 OAJ04429.1 - 0.063 13.0 2.0 0.075 12.8 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like Pkinase PF00069.20 OAJ04430.1 - 1.2e-70 237.6 0.0 1.6e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04430.1 - 1.5e-33 115.9 0.0 2.7e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04430.1 - 0.0014 18.3 0.0 0.0071 16.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ04430.1 - 0.0062 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 OAJ04430.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAJ04430.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Phage_integrase PF00589.17 OAJ04431.1 - 0.002 17.7 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase family Alpha-E PF04168.7 OAJ04432.1 - 0.052 12.9 0.6 0.051 12.9 0.4 1.0 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. NTPase_P4 PF11602.3 OAJ04432.1 - 0.14 11.0 1.0 0.16 10.9 0.7 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 Bud13 PF09736.4 OAJ04433.1 - 3.1e-44 150.7 5.4 3.1e-44 150.7 3.7 2.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF3350 PF11830.3 OAJ04433.1 - 0.0097 15.9 1.7 0.3 11.1 0.2 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3350) DUF3275 PF11679.3 OAJ04433.1 - 0.13 11.9 3.0 0.24 10.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RRM_1 PF00076.17 OAJ04434.1 - 1.2e-46 156.1 0.0 3.6e-23 80.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04434.1 - 4.9e-36 122.5 0.0 1.1e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04434.1 - 8.2e-22 76.8 0.0 2.5e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ04434.1 - 3.5e-05 23.6 0.0 0.014 15.2 0.0 2.8 2 0 0 2 2 2 2 RNA binding motif DUF2962 PF11176.3 OAJ04435.1 - 1.1e-37 129.0 0.1 1.4e-37 128.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) FdsD PF11390.3 OAJ04435.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD AIP3 PF03915.8 OAJ04436.1 - 2.4e-99 333.1 0.3 4.7e-99 332.1 0.2 1.5 1 1 0 1 1 1 1 Actin interacting protein 3 Syntaxin_2 PF14523.1 OAJ04436.1 - 0.014 15.4 0.5 12 5.9 0.0 3.4 3 1 0 3 3 3 0 Syntaxin-like protein IFT57 PF10498.4 OAJ04436.1 - 0.021 13.5 0.2 0.044 12.5 0.1 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Lectin_N PF03954.9 OAJ04436.1 - 0.022 14.1 1.1 0.056 12.8 0.0 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Halo_GVPC PF05465.8 OAJ04436.1 - 0.047 13.6 2.1 1.6 8.7 0.1 2.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat XPG_I_2 PF12813.2 OAJ04438.1 - 2.5e-08 33.7 0.0 4.3e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.12 OAJ04438.1 - 3.6e-05 23.9 0.0 7.8e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 OAJ04438.1 - 0.0042 17.0 1.1 0.012 15.6 0.0 2.3 2 0 0 2 2 2 1 XPG I-region Nucleoplasmin PF03066.10 OAJ04438.1 - 2.2 7.7 12.7 2.5 7.5 0.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin Spc97_Spc98 PF04130.8 OAJ04439.1 - 3.1e-38 131.4 0.0 1.4e-37 129.2 0.0 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family DHHW PF14286.1 OAJ04439.1 - 0.63 9.2 0.0 1.1 8.4 0.0 1.3 1 0 0 1 1 1 0 DHHW protein NOA36 PF06524.7 OAJ04439.1 - 7.9 5.6 5.0 16 4.5 3.5 1.4 1 0 0 1 1 1 0 NOA36 protein 4HBT_3 PF13622.1 OAJ04441.1 - 2e-27 96.5 0.4 8.7e-27 94.4 0.3 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ04441.1 - 0.00055 19.5 0.1 0.0012 18.4 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase 4HBT PF03061.17 OAJ04441.1 - 0.043 13.9 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Thioesterase superfamily SNAP PF14938.1 OAJ04442.1 - 1.7e-92 309.5 13.3 1.9e-92 309.4 9.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 OAJ04442.1 - 3.3e-06 26.6 18.6 0.00025 20.6 1.6 3.9 1 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 OAJ04442.1 - 5e-05 23.1 15.2 0.0047 16.8 1.0 4.3 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04442.1 - 0.0048 17.5 2.2 0.0048 17.5 1.5 4.6 3 1 2 5 5 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 OAJ04442.1 - 0.0077 15.1 3.4 0.091 11.6 0.5 2.1 1 1 1 2 2 2 1 Spatacsin C-terminus TPR_9 PF13371.1 OAJ04442.1 - 0.0087 15.8 6.2 1.1 9.1 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ04442.1 - 0.026 14.9 17.5 5.2 7.7 0.1 6.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ04442.1 - 0.097 13.0 13.7 0.22 11.9 2.0 4.0 1 1 3 4 4 4 0 Tetratricopeptide repeat PerC PF06069.6 OAJ04442.1 - 0.11 12.5 1.5 5.1 7.1 0.2 2.7 2 1 0 2 2 2 0 PerC transcriptional activator TPR_7 PF13176.1 OAJ04442.1 - 0.15 11.9 12.3 3.7 7.5 0.1 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF4170 PF13773.1 OAJ04442.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4170) TPR_2 PF07719.12 OAJ04442.1 - 0.23 11.4 18.4 5.2 7.2 0.1 6.9 3 3 6 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ04442.1 - 9.5 7.1 18.4 6.2 7.7 0.1 5.7 2 1 5 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ04442.1 - 9.7 6.2 12.6 13 5.8 0.2 5.0 4 1 3 7 7 6 0 Tetratricopeptide repeat NUC153 PF08159.7 OAJ04443.1 - 8.7e-08 31.6 0.0 8.7e-08 31.6 0.0 3.4 4 0 0 4 4 4 1 NUC153 domain BUD22 PF09073.5 OAJ04443.1 - 0.00013 21.1 19.7 0.00013 21.1 13.6 4.3 3 1 0 4 4 4 1 BUD22 TMEM51 PF15345.1 OAJ04443.1 - 0.0015 18.3 2.5 0.0015 18.3 1.8 2.8 2 1 0 2 2 2 1 Transmembrane protein 51 Spt5-NGN PF03439.8 OAJ04444.1 - 6.8e-19 67.3 0.0 1.5e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 OAJ04444.1 - 1.1e-10 42.0 11.9 1.1e-10 42.0 8.3 3.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 OAJ04444.1 - 1.7e-10 40.1 14.6 6.4e-05 22.5 0.2 5.6 6 0 0 6 6 6 3 KOW motif CTD PF12815.2 OAJ04444.1 - 1.3e-08 35.2 55.9 0.00011 22.5 25.5 4.4 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 YajC PF02699.10 OAJ04444.1 - 0.13 11.9 4.4 2.4 7.8 0.6 3.1 2 1 1 3 3 3 0 Preprotein translocase subunit HMG_box PF00505.14 OAJ04445.1 - 2.1e-06 27.8 0.9 2.1e-06 27.8 0.6 4.9 4 1 0 4 4 4 2 HMG (high mobility group) box FAD_binding_4 PF01565.18 OAJ04446.1 - 5.3e-26 90.7 3.8 5.3e-26 90.7 2.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 OAJ04446.1 - 4.4e-09 36.0 0.2 9e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Transposase_21 PF02992.9 OAJ04447.1 - 1.7e-22 79.6 0.0 3.3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ04447.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Utp14 PF04615.8 OAJ04452.1 - 3.8 5.5 43.2 4.9 5.1 29.9 1.0 1 0 0 1 1 1 0 Utp14 protein RHD3 PF05879.7 OAJ04459.1 - 3.3e-247 822.1 0.0 4.1e-247 821.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Miro PF08477.8 OAJ04459.1 - 1.6e-06 28.5 0.2 5.7e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein GBP PF02263.14 OAJ04459.1 - 1.2e-05 24.5 0.2 2.3e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 OAJ04459.1 - 1.8e-05 24.6 0.3 0.00012 21.9 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 OAJ04459.1 - 9.2e-05 22.3 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 OAJ04459.1 - 0.0027 17.7 0.0 0.0088 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ04459.1 - 0.008 16.1 0.3 1.4 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.13 OAJ04459.1 - 0.11 11.4 0.1 0.25 10.3 0.1 1.5 1 0 0 1 1 1 0 Septin DUF21 PF01595.15 OAJ04460.1 - 8.8e-35 119.6 1.8 8.8e-35 119.6 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 OAJ04460.1 - 3.1e-06 26.8 0.3 2.2 8.1 0.0 3.5 3 0 0 3 3 3 3 CBS domain Lyase_aromatic PF00221.14 OAJ04461.1 - 2.8e-128 428.3 2.6 4e-128 427.8 1.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase KAT11 PF08214.6 OAJ04462.1 - 2.3e-25 89.4 0.7 3.1e-13 49.5 0.0 4.0 4 0 0 4 4 4 3 Histone acetylation protein zf-PARP PF00645.13 OAJ04462.1 - 8e-21 74.0 0.0 1.5e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MIP-T3 PF10243.4 OAJ04462.1 - 1.5e-05 23.6 22.7 1.5e-05 23.6 15.8 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 OAJ04462.1 - 0.14 10.0 27.7 0.22 9.4 19.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2017 PF09438.5 OAJ04463.1 - 0.098 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) MFS_1 PF07690.11 OAJ04464.1 - 1.4e-34 119.4 35.3 5.9e-33 114.0 21.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ04464.1 - 1.2e-05 23.7 5.4 3.8e-05 22.1 2.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Rick_17kDa_Anti PF05433.10 OAJ04464.1 - 0.029 14.0 4.6 0.11 12.2 3.2 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain Cytomega_TRL10 PF06084.6 OAJ04464.1 - 0.21 11.3 0.9 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein DUF2340 PF10209.4 OAJ04465.1 - 1.1e-44 151.4 0.0 1.5e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) TBCA PF02970.11 OAJ04466.1 - 6.2e-27 93.5 6.6 6.2e-27 93.5 4.6 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A TaqI_C PF12950.2 OAJ04466.1 - 0.039 13.6 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain HN PF00423.14 OAJ04466.1 - 0.089 11.0 1.3 0.1 10.8 0.9 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Cytochrom_C_2 PF01322.15 OAJ04466.1 - 0.39 11.2 5.0 1.5 9.4 3.5 1.8 1 1 0 1 1 1 0 Cytochrome C' Fib_alpha PF08702.5 OAJ04466.1 - 2.4 8.2 7.4 1.6 8.8 0.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2547 PF10818.3 OAJ04466.1 - 6.2 7.5 8.7 0.63 10.7 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2547) Rad52_Rad22 PF04098.10 OAJ04467.1 - 3.2e-57 192.5 0.0 5e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SH2_2 PF14633.1 OAJ04468.1 - 3.6e-65 219.1 0.1 3.6e-65 219.1 0.0 2.3 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 OAJ04468.1 - 4.7e-24 84.7 0.0 4.7e-24 84.7 0.0 3.9 4 0 0 4 4 4 1 Death-like domain of SPT6 HHH_7 PF14635.1 OAJ04468.1 - 1.1e-22 80.1 0.0 2e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 OAJ04468.1 - 4.2e-20 71.8 0.0 1.6e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 OAJ04468.1 - 2.4e-18 66.0 30.0 2.4e-18 66.0 20.8 6.1 4 1 2 6 6 6 2 Acidic N-terminal SPT6 SH2 PF00017.19 OAJ04468.1 - 0.00059 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 OAJ04468.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HTH_44 PF14641.1 OAJ04468.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 MA3 PF02847.12 OAJ04468.1 - 0.055 13.1 0.2 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 MA3 domain CDC45 PF02724.9 OAJ04469.1 - 4.7e-183 609.6 0.0 5.2e-180 599.5 0.0 2.0 1 1 0 1 1 1 1 CDC45-like protein Glypican PF01153.14 OAJ04469.1 - 8.9 4.7 5.5 14 4.1 3.8 1.3 1 0 0 1 1 1 0 Glypican Fer2_3 PF13085.1 OAJ04471.1 - 1e-31 109.0 0.0 1.6e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 OAJ04471.1 - 7.7e-10 38.9 6.2 7.7e-10 38.9 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 OAJ04471.1 - 2.7e-09 36.9 5.0 2.7e-09 36.9 3.5 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 OAJ04471.1 - 0.00015 22.1 3.1 0.00015 22.1 2.1 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ04471.1 - 0.00017 21.7 5.5 0.04 14.1 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ04471.1 - 0.00026 20.7 4.5 0.00026 20.7 3.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 OAJ04471.1 - 0.011 15.4 1.4 0.011 15.4 1.0 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 OAJ04471.1 - 0.017 15.5 6.2 0.017 15.5 4.3 2.7 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 OAJ04471.1 - 0.13 12.8 4.8 1.8 9.1 0.2 2.9 3 0 0 3 3 3 0 4Fe-4S single cluster domain DNA_pol3_tau_4 PF12168.3 OAJ04471.1 - 1.6 9.1 4.9 1.8 8.9 1.2 2.3 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding PhyH PF05721.8 OAJ04472.1 - 7.3e-44 150.3 0.0 1.1e-43 149.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RRM_1 PF00076.17 OAJ04473.1 - 1.3e-10 40.7 0.0 3.5e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04473.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04473.1 - 1.9e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tetraspannin PF00335.15 OAJ04474.1 - 4.3e-17 62.1 7.1 5.6e-17 61.7 4.9 1.1 1 0 0 1 1 1 1 Tetraspanin family XRCC4 PF06632.7 OAJ04474.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 YL1_C PF08265.6 OAJ04475.1 - 3e-13 49.0 0.3 4.7e-13 48.4 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Sec2p PF06428.6 OAJ04476.1 - 9.3e-14 51.1 8.9 9.3e-14 51.1 6.2 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p fn1 PF00039.13 OAJ04477.1 - 0.068 12.9 1.7 0.1 12.4 0.1 2.0 2 0 0 2 2 2 0 Fibronectin type I domain zf-SNAP50_C PF12251.3 OAJ04477.1 - 0.12 11.7 1.0 0.15 11.3 0.7 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal TPPK_C PF12555.3 OAJ04477.1 - 2.5 7.9 8.0 1 9.1 0.9 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Tad PF13400.1 OAJ04477.1 - 4.6 7.3 8.1 0.41 10.7 0.4 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Transp_cyt_pur PF02133.10 OAJ04479.1 - 4.3e-17 61.7 29.2 5.6e-17 61.4 20.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3337 PF11816.3 OAJ04480.1 - 5.7e-41 141.0 0.0 1.3e-39 136.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 OAJ04480.1 - 1.6e-32 110.1 26.4 1.2e-09 37.6 0.1 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat RXT2_N PF08595.6 OAJ04480.1 - 0.011 15.5 0.3 0.011 15.5 0.2 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4632 PF15451.1 OAJ04480.1 - 0.085 12.7 0.0 0.085 12.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) Nup160 PF11715.3 OAJ04480.1 - 0.26 9.4 3.7 5.4 5.0 0.0 3.4 4 0 0 4 4 4 0 Nucleoporin Nup120/160 BSP_II PF05432.6 OAJ04480.1 - 3.1 6.9 14.5 0.048 12.9 4.2 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PUF PF00806.14 OAJ04481.1 - 9.2e-59 191.7 3.2 2.5e-08 32.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RRP7 PF12923.2 OAJ04482.1 - 1.9e-21 76.4 6.6 1.9e-21 76.4 4.6 2.8 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 OAJ04482.1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ins_P5_2-kin PF06090.7 OAJ04483.1 - 8e-45 153.2 0.0 1.6e-40 139.0 0.0 2.1 2 0 0 2 2 2 2 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.21 OAJ04483.1 - 2.7e-11 43.1 7.3 3.7e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ04483.1 - 3.6e-05 23.8 6.6 0.046 14.0 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ04483.1 - 0.00045 20.3 8.7 0.0005 20.2 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 OAJ04483.1 - 0.22 11.6 9.0 0.21 11.7 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 OAJ04483.1 - 0.3 11.0 2.0 7.9 6.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger AAA PF00004.24 OAJ04485.1 - 4.5e-84 279.2 0.0 1.2e-41 142.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ04485.1 - 6.8e-15 55.0 0.0 3.1e-06 26.9 0.0 4.5 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 OAJ04485.1 - 7e-13 48.1 0.0 4e-06 26.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ04485.1 - 2.1e-12 47.4 0.8 0.0011 18.9 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ04485.1 - 5e-11 42.8 0.1 0.00012 22.2 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 OAJ04485.1 - 1.4e-09 38.8 0.0 0.00017 22.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ04485.1 - 1.9e-08 33.9 2.0 0.017 14.4 0.1 4.2 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.8 OAJ04485.1 - 8.2e-08 31.3 0.0 0.00036 19.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 OAJ04485.1 - 1.6e-07 31.2 0.0 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ04485.1 - 3.7e-07 29.4 0.0 0.00053 19.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 OAJ04485.1 - 4.1e-07 29.6 3.1 0.00012 21.8 0.0 3.9 3 1 1 4 4 3 1 Part of AAA domain IstB_IS21 PF01695.12 OAJ04485.1 - 1.5e-06 27.7 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 OAJ04485.1 - 2.1e-06 27.7 0.0 0.13 12.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ04485.1 - 5.6e-06 26.2 0.0 0.0054 16.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 OAJ04485.1 - 1e-05 24.8 0.3 0.083 12.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAJ04485.1 - 2.9e-05 24.1 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 OAJ04485.1 - 7.5e-05 22.7 0.1 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 OAJ04485.1 - 0.00012 22.4 0.0 0.0069 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 OAJ04485.1 - 0.0003 20.8 0.0 0.29 11.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 OAJ04485.1 - 0.00054 19.6 0.1 0.041 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 OAJ04485.1 - 0.0012 17.6 0.1 0.19 10.3 0.0 3.0 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 OAJ04485.1 - 0.0014 18.3 0.0 4 7.0 0.0 3.4 3 1 0 4 4 4 1 NACHT domain AAA_11 PF13086.1 OAJ04485.1 - 0.0023 17.5 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 OAJ04485.1 - 0.0025 17.4 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 OAJ04485.1 - 0.0036 16.4 0.0 1.8 7.6 0.0 2.9 3 0 0 3 3 2 1 KaiC NTPase_1 PF03266.10 OAJ04485.1 - 0.0053 16.4 0.4 0.83 9.3 0.0 3.7 2 2 2 4 4 4 1 NTPase ABC_tran PF00005.22 OAJ04485.1 - 0.0055 17.0 0.3 0.72 10.1 0.0 3.5 4 0 0 4 4 2 1 ABC transporter Sigma54_activat PF00158.21 OAJ04485.1 - 0.006 16.0 0.0 6.6 6.1 0.0 3.6 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 OAJ04485.1 - 0.013 14.6 0.1 0.51 9.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_ab PF00006.20 OAJ04485.1 - 0.015 14.8 0.0 6.4 6.2 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 OAJ04485.1 - 0.022 13.6 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 OAJ04485.1 - 0.037 13.7 0.0 8.3 6.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 OAJ04485.1 - 0.068 13.0 0.0 9.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase DAP3 PF10236.4 OAJ04485.1 - 0.17 10.7 0.0 0.64 8.8 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF543 PF04418.7 OAJ04486.1 - 1.8e-28 98.2 0.4 4.2e-28 97.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF883 PF05957.8 OAJ04486.1 - 0.2 12.0 3.2 7.1 7.1 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GATA PF00320.22 OAJ04487.1 - 1.4e-12 46.6 5.7 3e-12 45.6 3.9 1.6 1 0 0 1 1 1 1 GATA zinc finger FAM163 PF15069.1 OAJ04487.1 - 0.085 13.4 0.4 0.085 13.4 0.3 1.9 2 0 0 2 2 2 0 FAM163 family DUF4201 PF13870.1 OAJ04488.1 - 0.047 13.1 1.6 0.06 12.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3811 PF11656.3 OAJ04488.1 - 0.069 13.2 5.2 0.086 12.9 3.6 1.2 1 0 0 1 1 1 0 YjbD family (DUF3811) DMPK_coil PF08826.5 OAJ04488.1 - 0.088 12.7 5.5 0.099 12.5 3.0 1.7 1 1 0 1 1 1 0 DMPK coiled coil domain like DUF4337 PF14235.1 OAJ04488.1 - 0.099 12.4 6.3 0.12 12.2 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.1 OAJ04488.1 - 0.45 9.4 5.1 0.51 9.2 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 OAJ04488.1 - 0.46 9.3 4.8 0.5 9.2 3.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SpaB_C PF14028.1 OAJ04488.1 - 0.88 9.0 9.0 0.94 8.9 6.3 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain ATP11 PF06644.6 OAJ04488.1 - 1 8.8 4.7 1.1 8.6 3.3 1.0 1 0 0 1 1 1 0 ATP11 protein DUF2040 PF09745.4 OAJ04489.1 - 2.5e-30 104.9 17.0 2.5e-30 104.9 11.8 3.1 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Peptidase_M13_N PF05649.8 OAJ04490.1 - 1.8e-85 287.3 0.0 2.3e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 OAJ04490.1 - 1.2e-55 187.9 0.0 1.8e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Sec7 PF01369.15 OAJ04491.1 - 6.8e-38 130.2 0.1 2.1e-37 128.6 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 OAJ04491.1 - 2.2e-28 98.8 0.0 5.6e-28 97.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ04491.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.7 1 1 0 1 1 1 1 PH domain zf-RING_UBOX PF13445.1 OAJ04493.1 - 9.4e-17 60.4 0.3 2.2e-16 59.2 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 OAJ04493.1 - 5.2e-12 45.6 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.1 OAJ04493.1 - 5.2e-05 22.8 0.6 0.00011 21.8 0.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ04493.1 - 0.00023 20.9 0.4 0.0005 19.8 0.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 OAJ04493.1 - 0.00034 20.3 0.6 0.00073 19.3 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ04493.1 - 0.0004 19.9 0.7 0.00072 19.1 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ04493.1 - 0.00055 19.9 1.0 0.0011 18.9 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ04493.1 - 0.0015 18.1 0.5 0.0033 17.0 0.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) COG6 PF06419.6 OAJ04493.1 - 0.0051 15.0 0.4 0.007 14.5 0.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PilJ PF13675.1 OAJ04493.1 - 0.028 14.7 0.2 0.1 12.8 0.0 2.1 2 1 0 2 2 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term LisH PF08513.6 OAJ04493.1 - 0.073 12.8 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 LisH FH2 PF02181.18 OAJ04493.1 - 0.11 11.3 0.2 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Myosin_tail_1 PF01576.14 OAJ04498.1 - 8e-05 20.5 1.1 0.00012 20.0 0.8 1.1 1 0 0 1 1 1 1 Myosin tail Lge1 PF11488.3 OAJ04498.1 - 0.041 14.0 1.3 0.041 14.0 0.9 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 OAJ04498.1 - 0.18 11.3 1.5 0.36 10.4 1.1 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 OAJ04498.1 - 0.24 10.3 2.3 0.43 9.5 1.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 OAJ04498.1 - 1.3 8.5 5.3 2.5 7.6 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator PIF1 PF05970.9 OAJ04501.1 - 3.3e-92 309.2 0.0 4.3e-92 308.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ04501.1 - 8.1e-60 201.7 0.0 1.3e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ04501.1 - 2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 OAJ04501.1 - 0.0072 15.4 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 OAJ04501.1 - 0.017 15.0 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 OAJ04501.1 - 0.034 13.8 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 OAJ04501.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.4 OAJ04501.1 - 0.27 9.8 0.1 0.9 8.0 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain zf-RING_2 PF13639.1 OAJ04502.1 - 1.2e-10 41.0 4.9 7.3e-09 35.3 0.4 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ04502.1 - 1.5e-06 28.1 0.2 1.5e-06 28.1 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ04502.1 - 1.1e-05 24.9 2.7 0.00023 20.7 0.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 OAJ04502.1 - 3.4e-05 23.8 1.7 0.00015 21.8 0.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 OAJ04502.1 - 7.8e-05 22.3 2.3 0.00029 20.5 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ04502.1 - 9.4e-05 22.0 4.1 0.0002 20.9 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 OAJ04502.1 - 0.004 16.8 0.2 0.004 16.8 0.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.6 OAJ04502.1 - 0.0092 15.9 0.5 0.018 14.9 0.3 1.4 1 0 0 1 1 1 1 RING-like domain zf-Apc11 PF12861.2 OAJ04502.1 - 0.043 13.6 0.1 0.043 13.6 0.1 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 OAJ04502.1 - 0.47 10.4 7.8 0.44 10.5 2.2 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 OAJ04502.1 - 1 8.9 3.5 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 OAJ04502.1 - 1.6 8.2 4.2 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.2 OAJ04502.1 - 1.8 8.6 7.0 0.28 11.2 1.0 2.3 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.1 OAJ04502.1 - 3.4 7.6 8.7 0.56 10.1 0.2 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 OAJ04502.1 - 4.5 6.8 7.1 0.26 10.7 0.7 2.0 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_4 PF14447.1 OAJ04502.1 - 5.4 6.6 7.2 0.87 9.1 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF1708 PF08101.6 OAJ04503.1 - 5e-15 55.2 0.0 1.4e-10 40.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ04503.1 - 0.043 13.4 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 RhoGAP domain Rab5ip PF07019.7 OAJ04505.1 - 1.7e-07 31.2 6.8 4.8e-07 29.8 4.7 1.6 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) F-box-like PF12937.2 OAJ04506.1 - 3.9e-05 23.2 0.0 0.00054 19.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ04506.1 - 0.00053 19.5 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain GCR1_C PF12550.3 OAJ04507.1 - 0.025 14.4 0.1 0.063 13.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Peptidase_M24 PF00557.19 OAJ04508.1 - 3.9e-40 137.6 0.0 5.4e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 OAJ04508.1 - 3.8e-20 72.7 0.0 7.7e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Ribosomal_S4 PF00163.14 OAJ04509.1 - 1.8e-11 44.2 0.5 2.8e-11 43.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ04509.1 - 3.6e-11 42.3 0.0 6.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain Fe_hyd_lg_C PF02906.9 OAJ04511.1 - 2.1e-58 197.8 0.0 9.7e-58 195.6 0.0 2.2 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HIG_1_N PF04588.8 OAJ04512.1 - 2e-06 27.4 1.3 3.8e-06 26.5 0.9 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ENOD93 PF03386.9 OAJ04512.1 - 0.01 15.5 0.7 0.022 14.4 0.1 1.8 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Peptidase_M24 PF00557.19 OAJ04513.1 - 2.1e-49 167.9 0.0 3.1e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 OAJ04513.1 - 4e-34 116.8 0.0 7.1e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Transposase_21 PF02992.9 OAJ04514.1 - 1.9e-22 79.4 0.0 3.5e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ04514.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Corona_nucleoca PF00937.13 OAJ04514.1 - 0.92 8.3 7.3 1.9 7.3 5.0 1.5 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Na_H_Exchanger PF00999.16 OAJ04516.1 - 2.5e-66 223.7 49.3 3.8e-66 223.1 34.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_4 PF02390.12 OAJ04517.1 - 1.9e-52 177.1 0.0 2.2e-39 134.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ04517.1 - 0.0069 16.9 0.0 0.15 12.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ04517.1 - 0.016 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ04517.1 - 0.074 13.4 0.0 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain BolA PF01722.13 OAJ04518.1 - 6.4e-29 99.7 0.4 8.1e-29 99.3 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein Response_reg PF00072.19 OAJ04519.1 - 1.6e-17 63.5 0.0 4.3e-10 39.5 0.0 3.7 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.21 OAJ04519.1 - 2.2e-17 62.8 0.3 6.4e-17 61.2 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ04519.1 - 5e-17 61.6 0.0 1.5e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 OAJ04519.1 - 0.00082 19.5 0.2 0.09 12.8 0.0 3.2 3 0 0 3 3 3 1 GAF domain IlvN PF07991.7 OAJ04520.1 - 7.3e-47 158.7 0.0 1.8e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 OAJ04520.1 - 8e-41 139.3 0.0 1.2e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 OAJ04520.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ04520.1 - 0.1 13.0 0.4 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent BATS PF06968.8 OAJ04521.1 - 1.9e-26 91.7 0.0 7.4e-26 89.8 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 OAJ04521.1 - 3.1e-13 50.2 0.1 5.2e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Opi1 PF08618.5 OAJ04522.1 - 5.2e-67 226.6 10.8 5.2e-67 226.6 7.5 4.4 4 2 1 5 5 5 1 Transcription factor Opi1 CNH PF00780.17 OAJ04523.1 - 1.7e-83 280.2 0.0 3e-83 279.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 OAJ04523.1 - 4e-46 156.3 0.0 8.6e-46 155.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 OAJ04523.1 - 6e-39 133.7 1.0 1.1e-38 132.9 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 OAJ04523.1 - 4.4e-12 45.5 0.0 9.2e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_10 PF15411.1 OAJ04523.1 - 0.02 15.0 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PIF1 PF05970.9 OAJ04525.1 - 1.8e-18 66.6 0.0 1.2e-17 63.9 0.0 1.8 1 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04525.1 - 1.1e-09 38.1 0.4 9.8e-09 35.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain Helitron_like_N PF14214.1 OAJ04525.1 - 2.1e-08 34.1 0.1 7.8e-08 32.2 0.0 2.0 2 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ04525.1 - 3.6e-07 29.8 2.9 1.2e-06 28.1 0.3 2.7 3 0 0 3 3 3 1 Part of AAA domain AAA_16 PF13191.1 OAJ04525.1 - 0.015 15.2 0.0 0.052 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ04525.1 - 0.058 13.5 0.2 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 OAJ04525.1 - 0.14 11.8 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) APG17 PF04108.7 OAJ04526.1 - 0.00058 18.7 1.1 0.0007 18.5 0.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 GrpE PF01025.14 OAJ04526.1 - 0.00082 18.9 1.0 0.0014 18.2 0.6 1.3 1 1 0 1 1 1 1 GrpE Baculo_PEP_C PF04513.7 OAJ04526.1 - 0.0056 16.5 8.0 0.19 11.5 2.0 2.3 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.4 OAJ04526.1 - 0.0095 14.5 0.1 0.011 14.3 0.1 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein MIF4G_like_2 PF09090.6 OAJ04526.1 - 0.018 14.2 0.5 0.022 13.9 0.4 1.2 1 0 0 1 1 1 0 MIF4G like DUF3618 PF12277.3 OAJ04526.1 - 0.031 14.3 1.1 0.077 13.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) Spc7 PF08317.6 OAJ04526.1 - 0.055 12.1 1.0 0.066 11.8 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Streptin-Immun PF11083.3 OAJ04526.1 - 0.075 13.0 1.2 0.33 10.9 0.4 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Phage_int_SAM_2 PF12834.2 OAJ04526.1 - 0.075 13.4 0.6 0.2 12.0 0.1 1.9 1 1 0 2 2 2 0 Phage integrase, N-terminal Bacillus_HBL PF05791.6 OAJ04526.1 - 0.13 11.5 1.3 0.26 10.6 0.6 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 OAJ04526.1 - 0.16 11.5 4.3 0.2 11.2 3.0 1.2 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 OAJ04526.1 - 0.7 9.7 2.8 1.3 8.8 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) AA_permease_2 PF13520.1 OAJ04527.1 - 8.7e-51 172.7 54.5 1.1e-50 172.4 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ04527.1 - 4.8e-12 44.9 42.4 4.8e-12 44.9 29.4 2.0 1 1 0 2 2 2 1 Amino acid permease TraQ PF09679.5 OAJ04527.1 - 0.0067 16.3 0.0 0.027 14.3 0.0 2.1 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) RNA_pol_A_bac PF01000.21 OAJ04528.1 - 8.5e-27 93.5 0.0 2.1e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 OAJ04528.1 - 1.8e-18 65.3 0.0 2.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 OAJ04528.1 - 0.0009 18.7 0.4 0.003 17.0 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF22 RNA_pol_L_2 PF13656.1 OAJ04528.1 - 0.078 12.4 0.1 0.99 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 OAJ04534.1 - 1.4e-52 178.4 0.0 1.4e-52 178.4 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04534.1 - 3.3e-20 72.2 0.0 8e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RR_TM4-6 PF06459.7 OAJ04534.1 - 1.6 8.5 28.9 1.9 8.3 7.6 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LRR_4 PF12799.2 OAJ04535.1 - 3.8e-51 170.0 58.6 1.4e-08 34.1 0.5 13.2 6 4 4 13 13 13 12 Leucine Rich repeats (2 copies) PP2C PF00481.16 OAJ04535.1 - 2.1e-47 161.6 0.1 3.7e-47 160.8 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 OAJ04535.1 - 4.8e-42 141.5 52.9 1.2e-10 40.9 0.7 9.4 5 2 7 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 OAJ04535.1 - 1.6e-24 86.3 0.0 2.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 OAJ04535.1 - 3.8e-20 68.8 58.0 0.032 14.2 0.0 20.0 21 1 0 21 21 21 8 Leucine Rich Repeat LRR_7 PF13504.1 OAJ04535.1 - 2.4e-09 35.8 48.5 1.6 9.2 0.0 17.6 19 0 0 19 19 19 3 Leucine rich repeat RA PF00788.18 OAJ04535.1 - 9.2e-08 32.4 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 OAJ04535.1 - 0.00039 20.2 52.7 2.1 8.6 0.1 16.0 18 0 0 18 18 18 1 Leucine Rich repeat LRR_5 PF13306.1 OAJ04535.1 - 0.011 15.4 1.7 6.1 6.5 0.0 3.5 2 1 2 4 4 4 0 Leucine rich repeats (6 copies) Mg_trans_NIPA PF05653.9 OAJ04536.1 - 1.7e-94 316.1 21.8 2.6e-94 315.5 15.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 OAJ04536.1 - 9.4e-05 22.5 8.6 9.4e-05 22.5 6.0 3.4 1 1 2 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 OAJ04536.1 - 0.0041 17.1 12.3 0.0041 17.1 8.5 3.2 2 2 0 2 2 2 1 EamA-like transporter family DUF3671 PF12420.3 OAJ04536.1 - 1.4 8.9 5.1 8.8 6.3 3.5 2.3 1 1 0 1 1 1 0 Protein of unknown function COesterase PF00135.23 OAJ04537.1 - 4.9e-92 309.3 0.0 5.6e-92 309.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ04537.1 - 0.00019 21.1 0.0 0.00045 19.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold RVT_1 PF00078.22 OAJ04538.1 - 2.4e-17 63.0 0.0 5.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04538.1 - 8e-17 61.4 0.0 2.8e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ04538.1 - 0.0013 18.2 0.1 0.0059 16.1 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAJ04538.1 - 0.002 17.9 3.7 0.002 17.9 2.6 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ04538.1 - 0.016 14.6 0.5 0.038 13.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 OAJ04538.1 - 0.027 14.9 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 OAJ04538.1 - 0.03 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF687 PF05095.7 OAJ04538.1 - 0.63 8.3 0.0 1.1 7.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) Abhydrolase_3 PF07859.8 OAJ04539.1 - 2.6e-32 112.1 0.5 1.5e-22 80.1 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_26 PF13659.1 OAJ04541.1 - 7.3e-15 55.0 0.1 1.4e-14 54.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ04541.1 - 3e-10 39.8 0.0 5.4e-10 39.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ04541.1 - 3e-08 34.2 0.0 4.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 OAJ04541.1 - 2.6e-06 26.7 0.0 3.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.1 OAJ04541.1 - 4e-06 27.1 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ04541.1 - 1.3e-05 24.6 0.8 0.0019 17.6 0.0 3.1 2 1 1 3 3 3 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ04541.1 - 0.00013 21.6 0.0 0.0015 18.0 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 OAJ04541.1 - 0.011 14.9 0.0 0.022 13.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 OAJ04541.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 OAJ04541.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 OAJ04541.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_10 PF05971.7 OAJ04541.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF890) Methyltransf_12 PF08242.7 OAJ04541.1 - 0.06 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ04541.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 OAJ04541.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Rhomboid PF01694.17 OAJ04543.1 - 2.9e-29 101.9 14.3 2.9e-29 101.9 9.9 2.2 3 0 0 3 3 3 1 Rhomboid family DUF3818 PF12825.2 OAJ04544.1 - 1.3e-115 385.7 0.0 2e-115 385.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 OAJ04544.1 - 1.6e-39 134.6 0.2 3.2e-39 133.6 0.2 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 OAJ04544.1 - 2.8e-08 33.5 0.0 1.2e-07 31.4 0.0 2.1 2 1 0 2 2 2 1 PX domain Abhydrolase_3 PF07859.8 OAJ04545.1 - 4.6e-41 140.7 0.4 3.5e-40 137.8 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 OAJ04545.1 - 5.2e-09 35.3 0.0 1.5e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 OAJ04545.1 - 0.00066 19.4 0.0 0.0042 16.8 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 OAJ04545.1 - 0.0036 16.0 0.0 0.0055 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 OAJ04545.1 - 0.027 13.6 0.0 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 OAJ04545.1 - 0.16 10.3 0.0 7.8 4.8 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-C2H2_2 PF12756.2 OAJ04546.1 - 3.1e-38 129.9 3.3 4.2e-29 100.6 0.0 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 OAJ04546.1 - 7.4e-09 35.5 6.6 1.5e-08 34.5 1.8 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 OAJ04546.1 - 6.8e-08 32.4 11.7 1.1e-06 28.6 2.2 3.6 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 OAJ04546.1 - 0.0026 18.0 17.1 0.087 13.2 0.6 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type AKAP95 PF04988.7 OAJ04546.1 - 0.0036 17.0 1.0 0.0091 15.7 0.7 1.7 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 OAJ04546.1 - 0.01 15.7 7.4 2.2 8.3 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 OAJ04546.1 - 0.015 15.5 16.8 0.32 11.4 0.3 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.10 OAJ04546.1 - 0.088 12.5 1.4 0.71 9.6 0.2 2.6 2 0 0 2 2 2 0 BED zinc finger zf-DBF PF07535.7 OAJ04546.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.7 3 0 0 3 3 3 0 DBF zinc finger RAP1 PF07218.6 OAJ04547.1 - 5 5.0 5.8 6.1 4.7 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 OAJ04548.1 - 6e-44 150.1 0.0 2.2e-34 118.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04548.1 - 2.7e-24 85.6 0.0 5.3e-19 68.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04548.1 - 0.01 14.8 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like TBP PF00352.16 OAJ04548.1 - 0.26 10.6 0.1 0.51 9.7 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) tRNA-synt_2 PF00152.15 OAJ04549.1 - 1e-73 248.0 0.1 1.4e-73 247.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 OAJ04549.1 - 7.5e-18 64.3 0.1 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 OAJ04549.1 - 6.1e-05 22.3 0.9 0.29 10.2 0.2 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 OAJ04549.1 - 0.0023 17.7 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ERM PF00769.14 OAJ04549.1 - 0.0073 15.8 7.7 0.22 11.0 0.1 2.4 2 0 0 2 2 2 2 Ezrin/radixin/moesin family Cwf_Cwc_15 PF04889.7 OAJ04549.1 - 0.025 14.3 0.1 0.025 14.3 0.0 3.5 3 1 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 OAJ04549.1 - 0.088 13.0 15.0 0.025 14.7 4.0 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ04549.1 - 0.44 10.0 11.1 0.21 11.0 3.3 2.6 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 OAJ04549.1 - 1.5 6.7 8.1 0.071 11.1 1.2 2.0 2 0 0 2 2 2 0 CDC45-like protein NOA36 PF06524.7 OAJ04549.1 - 7.3 5.7 13.7 2.3 7.3 6.7 2.0 2 0 0 2 2 2 0 NOA36 protein KH_1 PF00013.24 OAJ04550.1 - 1.1e-06 28.2 0.5 1.5e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 OAJ04550.1 - 3.4e-05 23.3 1.3 6.5e-05 22.4 0.9 1.6 1 1 0 1 1 1 1 KH domain KH_5 PF13184.1 OAJ04550.1 - 0.053 13.3 0.0 0.089 12.6 0.0 1.7 1 1 0 1 1 1 0 NusA-like KH domain DDE_Tnp_4 PF13359.1 OAJ04551.1 - 8.4e-14 51.4 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease FHA PF00498.21 OAJ04552.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 FHA domain Pkinase PF00069.20 OAJ04553.1 - 9.2e-30 103.6 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04553.1 - 3.2e-20 72.2 0.0 4.4e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ04553.1 - 2.1e-05 24.3 2.1 0.042 13.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ04553.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 OAJ04553.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBA PF00627.26 OAJ04554.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain RVT_1 PF00078.22 OAJ04555.1 - 4.1e-18 65.5 0.0 8.3e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ04555.1 - 3e-15 56.3 0.0 8.8e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ04555.1 - 8.8e-06 26.1 0.0 0.00022 21.6 0.0 2.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ04555.1 - 0.036 13.9 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Phospholip_B PF04916.8 OAJ04555.1 - 0.11 10.6 0.0 0.17 9.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B RVT_2 PF07727.9 OAJ04556.1 - 1.8e-28 99.1 0.0 2.2e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SP2 PF03014.9 OAJ04557.1 - 2 6.1 5.9 2 6.1 4.1 1.0 1 0 0 1 1 1 0 Structural protein 2 Glyco_hydro_80 PF13647.1 OAJ04558.1 - 0.11 11.7 2.5 1.7 7.8 0.1 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 80 of chitosanase A YjgP_YjgQ PF03739.9 OAJ04559.1 - 0.023 13.4 0.0 0.046 12.4 0.0 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family LSM PF01423.17 OAJ04560.1 - 6.3e-13 48.0 0.0 9.6e-13 47.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ04560.1 - 7e-05 22.6 0.0 8.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2642 PF10842.3 OAJ04560.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) GCR1_C PF12550.3 OAJ04567.1 - 6.7e-09 35.4 0.2 1.5e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_integrase PF00589.17 OAJ04567.1 - 3.6e-07 30.0 0.1 3.2e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Phage integrase family Ribosomal_S13_N PF08069.7 OAJ04567.1 - 0.088 12.6 0.0 0.36 10.7 0.0 2.1 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Chitin_synth_2 PF03142.10 OAJ04569.1 - 2.3e-234 778.6 0.0 3.2e-234 778.2 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ04569.1 - 5.9e-14 52.2 10.9 5.9e-14 52.2 7.5 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ04569.1 - 2.5e-12 47.0 0.1 1.1e-11 45.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ04569.1 - 0.00012 21.3 0.2 0.17 11.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Cyt-b5 PF00173.23 OAJ04569.1 - 0.015 15.0 0.1 0.083 12.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 OAJ04569.1 - 0.079 12.6 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF3149 PF11346.3 OAJ04569.1 - 0.41 10.2 5.3 0.24 11.0 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) TPR_11 PF13414.1 OAJ04570.1 - 5.3e-38 128.5 44.6 4.5e-11 42.2 0.4 13.1 10 4 2 12 12 12 10 TPR repeat TPR_2 PF07719.12 OAJ04570.1 - 5.6e-30 100.8 55.4 5.7e-05 22.7 0.5 17.4 17 0 0 17 17 17 8 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ04570.1 - 2.5e-29 99.6 27.4 3.5e-05 23.2 0.2 13.8 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ04570.1 - 9.9e-23 78.1 17.4 0.019 14.7 0.1 13.2 14 1 1 15 15 15 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04570.1 - 2.1e-21 75.9 100.2 1.7e-06 28.5 0.6 17.7 14 4 5 19 19 19 6 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ04570.1 - 4.8e-20 70.2 75.0 0.00045 20.6 0.1 19.2 15 6 5 20 20 19 7 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ04570.1 - 5.3e-20 69.8 28.2 0.025 14.7 0.0 15.4 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04570.1 - 1.2e-18 66.8 55.1 3.8e-08 33.1 0.5 12.7 10 3 2 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ04570.1 - 9.7e-10 38.2 36.0 0.27 11.7 0.0 13.3 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ04570.1 - 2.1e-08 33.3 35.0 0.099 12.4 0.0 11.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ04570.1 - 9.5e-07 29.0 48.8 0.2 12.0 0.1 12.3 9 4 4 13 13 13 4 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ04570.1 - 0.00016 21.4 32.8 0.39 10.6 0.1 10.6 10 1 1 11 11 11 3 Tetratricopeptide repeat ChAPs PF09295.5 OAJ04570.1 - 0.47 9.1 4.2 6.9 5.3 0.0 3.2 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) FYVE PF01363.16 OAJ04571.1 - 6.1e-19 67.6 8.7 9.2e-19 67.1 6.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger FAM176 PF14851.1 OAJ04571.1 - 0.03 13.9 0.3 0.054 13.1 0.2 1.3 1 0 0 1 1 1 0 FAM176 family FYVE_2 PF02318.11 OAJ04571.1 - 0.18 11.7 5.7 0.32 10.8 3.9 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2890 PF11081.3 OAJ04571.1 - 0.36 10.8 2.4 0.57 10.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 OAJ04571.1 - 0.82 7.6 1.6 1.1 7.2 1.1 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RING_5 PF14634.1 OAJ04571.1 - 6.3 6.6 8.1 35 4.2 6.0 1.9 1 1 1 2 2 2 0 zinc-RING finger domain CENP-B_dimeris PF09026.5 OAJ04571.1 - 7.3 6.8 9.6 17 5.6 6.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCR1_C PF12550.3 OAJ04572.1 - 6.7e-09 35.4 0.2 1.5e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Phage_integrase PF00589.17 OAJ04572.1 - 3.6e-07 30.0 0.1 3.2e-06 26.9 0.0 2.6 2 1 0 2 2 2 1 Phage integrase family Ribosomal_S13_N PF08069.7 OAJ04572.1 - 0.088 12.6 0.0 0.36 10.7 0.0 2.1 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain DSPc PF00782.15 OAJ04574.1 - 7.5e-06 25.5 0.0 1.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ04574.1 - 0.0013 18.0 4.0 0.0099 15.2 0.0 2.5 3 0 0 3 3 3 2 Protein-tyrosine phosphatase UBN2 PF14223.1 OAJ04575.1 - 0.00071 19.3 0.0 0.0034 17.1 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ04575.1 - 0.08 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MULE PF10551.4 OAJ04576.1 - 2.5e-18 65.9 0.0 4.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 OAJ04576.1 - 4.5e-11 41.9 0.2 8.9e-11 40.9 0.0 1.6 2 0 0 2 2 2 1 Transposase, Mutator family SWIM PF04434.12 OAJ04576.1 - 5.1e-05 22.6 0.1 5.1e-05 22.6 0.1 2.1 3 0 0 3 3 3 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.12 OAJ04576.1 - 0.039 13.5 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Transposase GYF PF02213.11 OAJ04577.1 - 0.0012 18.3 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 GYF domain Catalase PF00199.14 OAJ04578.1 - 2.5e-149 497.1 0.1 3.2e-149 496.8 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ04578.1 - 3.5e-13 49.2 0.0 9.1e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Pkinase PF00069.20 OAJ04579.1 - 2.6e-72 243.1 0.0 2.9e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04579.1 - 1.2e-32 113.0 0.0 1.5e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04579.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ04579.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ04579.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tuberculin PF12198.3 OAJ04580.1 - 0.0038 17.0 3.5 0.016 15.0 2.5 2.1 1 0 0 1 1 1 1 Theoretical tuberculin protein His_Phos_2 PF00328.17 OAJ04581.1 - 2.2e-22 79.8 0.0 3.8e-22 79.0 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Tim17 PF02466.14 OAJ04582.1 - 1e-18 67.5 0.0 1.7e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MRP-S33 PF08293.6 OAJ04583.1 - 3.6e-14 52.4 0.6 3.5e-12 46.1 0.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 RCC1 PF00415.13 OAJ04584.1 - 6.2e-07 29.5 3.7 1.9 8.7 0.0 6.3 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ04584.1 - 0.00067 19.1 12.2 0.046 13.3 0.7 5.8 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.28 OAJ04584.1 - 0.003 17.1 0.4 0.0068 16.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ04584.1 - 0.014 15.0 1.1 0.038 13.7 0.8 1.8 1 0 0 1 1 1 0 F-box-like TRAPPC9-Trs120 PF08626.6 OAJ04585.1 - 3.8e-89 299.4 0.0 5e-74 249.4 0.0 4.0 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Transglut_C PF00927.17 OAJ04585.1 - 0.0096 15.9 0.1 0.064 13.3 0.0 2.4 3 0 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain Zn_clus PF00172.13 OAJ04586.1 - 1.6e-05 24.7 8.0 0.00016 21.4 5.5 2.1 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_tail_1 PF01576.14 OAJ04586.1 - 0.033 11.9 0.8 0.046 11.4 0.5 1.1 1 0 0 1 1 1 0 Myosin tail DUF4632 PF15451.1 OAJ04586.1 - 0.31 11.0 5.2 0.51 10.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) COX17 PF05051.8 OAJ04587.1 - 0.00014 21.7 1.2 0.014 15.3 0.1 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 OAJ04587.1 - 0.00016 21.3 6.8 0.069 12.9 0.5 3.1 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 OAJ04587.1 - 0.0027 17.5 7.2 0.051 13.5 2.2 3.3 2 2 1 3 3 3 2 CHCH domain YbfN PF13982.1 OAJ04587.1 - 0.083 13.0 1.4 4.1 7.6 0.1 2.6 1 1 1 2 2 2 0 YbfN-like lipoprotein UCR_hinge PF02320.11 OAJ04587.1 - 0.24 11.3 6.6 8.4 6.4 0.1 3.5 2 2 2 4 4 4 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 OAJ04587.1 - 1.1 9.1 6.7 16 5.4 0.1 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0203) Tyr-DNA_phospho PF06087.7 OAJ04588.1 - 7.3e-35 120.4 0.0 5.2e-23 81.3 0.0 3.5 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Fungal_trans PF04082.13 OAJ04589.1 - 6.6e-06 25.1 0.1 1.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ04589.1 - 0.0033 17.2 6.7 0.27 11.1 0.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain COX15-CtaA PF02628.10 OAJ04591.1 - 1.8e-78 263.5 1.5 4.4e-78 262.2 1.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein MIP PF00230.15 OAJ04592.1 - 1.7e-46 158.5 6.0 2.3e-46 158.0 4.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein TRAPP PF04051.11 OAJ04593.1 - 3.8e-33 114.1 0.0 4.5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cactin_mid PF10312.4 OAJ04594.1 - 2.1e-61 206.5 1.3 2.1e-61 206.5 0.9 2.1 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 OAJ04594.1 - 1.7e-54 182.7 6.4 2.9e-54 181.9 4.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein FtsJ PF01728.14 OAJ04595.1 - 2.4e-55 187.3 0.0 3.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 OAJ04595.1 - 0.00017 21.2 0.0 0.0014 18.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ04595.1 - 0.00028 21.4 0.0 0.0025 18.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ04595.1 - 0.00059 20.1 0.0 0.0019 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ04595.1 - 0.02 13.9 0.0 0.11 11.6 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family WD40 PF00400.27 OAJ04596.1 - 4.2e-49 162.7 16.4 3.8e-09 36.0 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ04596.1 - 7.2e-05 21.1 2.6 0.095 10.8 0.4 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 OAJ04596.1 - 0.023 14.9 1.6 38 4.7 0.0 4.1 3 1 0 3 3 3 0 PQQ-like domain Arena_nucleocap PF00843.12 OAJ04596.1 - 0.033 12.0 0.2 1.4 6.6 0.0 2.1 1 1 1 2 2 2 0 Arenavirus nucleocapsid protein CLTH PF10607.4 OAJ04596.1 - 0.13 11.9 0.3 0.23 11.1 0.2 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Ribosomal_L3 PF00297.17 OAJ04597.1 - 2.5e-119 397.5 5.1 3e-119 397.2 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DnaJ PF00226.26 OAJ04598.1 - 6.7e-20 70.5 0.1 1.1e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Mur_ligase_M PF08245.7 OAJ04599.1 - 4.4e-07 30.1 0.3 3e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 OAJ04599.1 - 0.024 14.6 0.0 0.15 12.1 0.0 2.4 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain DUF202 PF02656.10 OAJ04600.1 - 1.1e-12 48.0 5.4 1.1e-12 48.0 3.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 OAJ04600.1 - 0.31 9.5 2.1 0.21 10.1 0.7 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 OAJ04600.1 - 0.32 10.9 4.0 0.34 10.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) LHC PF00556.15 OAJ04600.1 - 0.34 10.7 0.2 0.34 10.7 0.2 2.3 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit RhoGEF PF00621.15 OAJ04601.1 - 1.8e-36 125.6 0.0 3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 OAJ04601.1 - 4.8e-10 39.5 0.0 9.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 PH domain Glt_symporter PF03616.9 OAJ04601.1 - 0.2 10.0 1.5 0.32 9.4 1.0 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter PCI_Csn8 PF10075.4 OAJ04602.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 SRP54_N PF02881.14 OAJ04602.1 - 0.13 12.3 0.4 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain ParA PF10609.4 OAJ04603.1 - 3.1e-32 110.3 0.0 6.4e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ04603.1 - 6.3e-07 29.0 2.3 0.002 17.5 0.6 2.7 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 OAJ04603.1 - 0.001 18.1 0.5 0.002 17.2 0.3 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 OAJ04603.1 - 0.008 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ04603.1 - 0.0099 15.0 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 OAJ04603.1 - 0.049 12.8 0.0 4.5 6.3 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 OAJ04603.1 - 0.085 12.4 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAJ04603.1 - 0.086 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.6 OAJ04603.1 - 0.23 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.22 OAJ04604.1 - 2.4e-43 147.6 0.0 6.1e-24 84.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ04604.1 - 4.7e-34 118.0 17.2 3.1e-20 72.7 2.5 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ04604.1 - 2.4e-09 36.7 0.0 0.00017 20.9 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ04604.1 - 3.3e-05 23.3 0.5 0.11 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 OAJ04604.1 - 3.8e-05 23.8 0.0 1.7 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 OAJ04604.1 - 6.1e-05 23.1 0.2 0.29 11.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 OAJ04604.1 - 8.1e-05 21.6 0.0 0.03 13.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 OAJ04604.1 - 0.00085 18.8 0.3 0.051 13.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 OAJ04604.1 - 0.0071 15.8 0.0 0.65 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain KaiC PF06745.8 OAJ04604.1 - 0.0074 15.4 0.2 0.36 9.9 0.0 2.3 2 0 0 2 2 2 1 KaiC DEAD PF00270.24 OAJ04604.1 - 0.097 12.1 0.0 3 7.3 0.0 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 OAJ04604.1 - 0.17 11.1 0.1 4.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 OAJ04604.1 - 0.28 10.6 1.6 0.98 8.8 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 OAJ04604.1 - 0.32 11.2 9.8 2.1 8.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 OAJ04604.1 - 0.33 10.8 15.5 0.0095 15.9 1.0 4.4 4 1 0 4 4 4 0 AAA ATPase domain DUF258 PF03193.11 OAJ04604.1 - 0.34 10.0 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 OAJ04604.1 - 1.1 8.9 4.7 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 OAJ04604.1 - 5.1 7.9 7.0 0.81 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain NUDIX PF00293.23 OAJ04605.1 - 6.1e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank PF00023.25 OAJ04606.1 - 2.9e-06 26.8 0.1 0.0032 17.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAJ04606.1 - 8.2e-06 26.0 0.1 0.0001 22.5 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ04606.1 - 9.5e-05 22.7 0.2 0.00045 20.6 0.1 2.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ04606.1 - 0.00097 19.1 0.0 0.033 14.4 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 OAJ04606.1 - 0.1 12.8 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) eIF-6 PF01912.13 OAJ04607.1 - 8.3e-81 269.8 0.3 9.7e-81 269.6 0.2 1.0 1 0 0 1 1 1 1 eIF-6 family CENP-Q PF13094.1 OAJ04616.1 - 0.0056 16.7 2.1 0.02 14.9 0.2 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Lipoprotein_6 PF01441.14 OAJ04616.1 - 0.0068 16.2 0.6 0.031 14.1 0.0 1.9 2 0 0 2 2 2 1 Lipoprotein Leu_zip PF15294.1 OAJ04616.1 - 0.027 13.5 0.2 0.037 13.1 0.1 1.4 1 1 0 1 1 1 0 Leucine zipper FlaC_arch PF05377.6 OAJ04616.1 - 0.029 14.2 0.1 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MtrG PF04210.8 OAJ04616.1 - 0.094 12.3 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G LEAP-2 PF07359.6 OAJ04617.1 - 0.044 13.4 8.2 2 8.1 0.1 4.1 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Neur_chan_memb PF02932.11 OAJ04620.1 - 1.7 8.4 5.3 3.7 7.3 3.7 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dimer_Tnp_hAT PF05699.9 OAJ04621.1 - 1.2e-23 82.4 0.2 4.1e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 OAJ04621.1 - 2.6e-07 30.2 2.0 5.8e-07 29.1 1.4 1.6 1 0 0 1 1 1 1 BED zinc finger DUF59 PF01883.14 OAJ04621.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF59 FUSC_2 PF13515.1 OAJ04622.1 - 1.5e-22 79.9 7.2 1.5e-22 79.9 5.0 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 OAJ04622.1 - 2.6e-15 55.9 4.2 9.4e-11 40.9 0.3 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 OAJ04622.1 - 4e-10 38.8 4.3 4e-10 38.8 3.0 2.9 2 1 2 4 4 4 1 Fusaric acid resistance protein family DUF2421 PF10334.4 OAJ04622.1 - 2.3e-08 33.9 0.4 1.3e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 OAJ04622.1 - 0.00043 20.1 4.0 0.00043 20.1 2.8 2.5 2 2 0 2 2 2 1 Bacterial protein of unknown function (DUF939) DASH_Duo1 PF08651.5 OAJ04622.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 AAA_13 PF13166.1 OAJ04622.1 - 0.28 9.6 0.1 0.58 8.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain FUSC-like PF12805.2 OAJ04622.1 - 1.1 8.1 4.1 14 4.4 1.5 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF1469 PF07332.6 OAJ04622.1 - 2.3 7.9 7.4 8.5 6.1 5.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) SNF2_N PF00176.18 OAJ04623.1 - 1.2e-32 112.9 0.0 1.9e-31 108.9 0.0 2.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ04623.1 - 0.00026 20.7 0.1 0.001 18.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PNP_UDP_1 PF01048.15 OAJ04624.1 - 9.5e-31 106.5 4.9 7.5e-30 103.6 3.4 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily FAD_binding_7 PF03441.9 OAJ04625.1 - 2.5e-60 204.0 1.0 4e-60 203.3 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ04625.1 - 2e-21 76.4 0.0 4.7e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase EMP70 PF02990.11 OAJ04626.1 - 1.5e-168 561.5 0.1 1.8e-168 561.2 0.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NPBW PF15180.1 OAJ04626.1 - 0.17 11.5 0.2 0.45 10.1 0.2 1.7 1 0 0 1 1 1 0 Neuropeptides B and W tRNA_int_endo PF01974.12 OAJ04628.1 - 5.7e-19 67.6 0.0 9.7e-19 66.9 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain MAGE_N PF12440.3 OAJ04628.1 - 0.59 10.4 5.2 0.94 9.8 3.6 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal RF-1 PF00472.15 OAJ04629.1 - 2.4e-13 49.8 0.4 3.6e-13 49.2 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain DUF1509 PF07420.6 OAJ04629.1 - 0.007 15.6 4.5 0.0085 15.4 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Sec23_trunk PF04811.10 OAJ04630.1 - 1.1e-76 257.3 0.0 1.6e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ04630.1 - 1.2e-34 117.8 0.3 2.1e-34 117.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ04630.1 - 4.2e-31 107.3 0.0 7.6e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ04630.1 - 6.7e-17 60.7 6.2 1.2e-16 59.9 4.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ04630.1 - 2.9e-13 49.2 0.0 6.2e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF3268 PF11672.3 OAJ04631.1 - 1.4 9.0 4.8 1.8 8.6 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3268) ATP_bind_3 PF01171.15 OAJ04632.1 - 0.001 18.6 0.3 0.0058 16.1 0.1 2.2 1 1 1 2 2 2 1 PP-loop family Cytochrom_B_N PF00033.14 OAJ04634.1 - 0.00045 19.6 4.7 0.00075 18.9 3.3 1.4 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 OAJ04634.1 - 0.04 13.2 2.8 0.063 12.6 1.9 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 7tm_7 PF08395.7 OAJ04634.1 - 0.33 9.9 2.5 0.47 9.4 1.7 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor MARVEL PF01284.18 OAJ04634.1 - 6.8 6.5 10.3 13 5.5 7.2 1.5 1 0 0 1 1 1 0 Membrane-associating domain Pox_A14 PF05767.7 OAJ04634.1 - 7.1 6.6 7.4 1.5 8.8 1.2 2.3 1 1 0 2 2 2 0 Poxvirus virion envelope protein A14 DHquinase_I PF01487.10 OAJ04636.1 - 1.1e-40 139.7 0.0 3.2e-40 138.1 0.0 1.9 2 1 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 OAJ04636.1 - 1.4e-23 83.5 0.0 2.3e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 OAJ04636.1 - 0.00038 21.2 0.0 0.00092 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ04636.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 OAJ04636.1 - 0.26 11.2 0.3 0.73 9.7 0.2 1.8 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.16 OAJ04637.1 - 8.8e-51 172.6 11.7 1.1e-50 172.2 8.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 OAJ04637.1 - 0.045 13.6 2.6 0.14 12.0 0.0 2.6 2 0 0 2 2 2 0 YrhC-like protein QueF_N PF14819.1 OAJ04638.1 - 1.8e-08 34.4 0.5 0.45 10.6 0.0 4.6 3 1 1 4 4 4 4 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DNA_Packaging_2 PF11123.3 OAJ04638.1 - 0.0016 18.2 0.1 39 4.2 0.0 5.4 3 2 4 7 7 7 1 DNA packaging protein DUF1018 PF06252.7 OAJ04638.1 - 0.0029 18.1 2.0 33 5.0 0.1 4.7 3 2 1 4 4 4 1 Protein of unknown function (DUF1018) Guanylate_kin PF00625.16 OAJ04639.1 - 2.6e-56 189.9 0.0 3.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 OAJ04639.1 - 1.6e-08 34.7 0.1 1.2e-07 31.9 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ04639.1 - 3.6e-07 30.4 0.0 5.7e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ04639.1 - 7.4e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 OAJ04639.1 - 1.3e-05 24.4 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAJ04639.1 - 5.1e-05 23.1 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ04639.1 - 5.1e-05 24.0 0.0 7.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ04639.1 - 6.9e-05 22.4 0.0 0.0004 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 OAJ04639.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.5 2 0 0 2 2 1 1 ABC transporter AAA_14 PF13173.1 OAJ04639.1 - 0.00053 19.8 0.0 0.00071 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 OAJ04639.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 OAJ04639.1 - 0.0023 17.8 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 OAJ04639.1 - 0.0042 16.7 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 OAJ04639.1 - 0.0049 17.3 0.0 0.0097 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein RNA_helicase PF00910.17 OAJ04639.1 - 0.0071 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 OAJ04639.1 - 0.0088 15.5 0.1 0.019 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 OAJ04639.1 - 0.0089 16.0 0.1 0.027 14.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 OAJ04639.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.6 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.9 OAJ04639.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 OAJ04639.1 - 0.033 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 OAJ04639.1 - 0.047 12.7 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Septin AAA PF00004.24 OAJ04639.1 - 0.051 13.7 0.0 0.079 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ04639.1 - 0.077 11.6 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PTS_IIB PF02302.12 OAJ04639.1 - 0.092 13.2 0.0 0.39 11.2 0.0 2.1 3 0 0 3 3 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Gtr1_RagA PF04670.7 OAJ04639.1 - 0.097 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 OAJ04639.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 OAJ04639.1 - 0.11 12.0 0.0 0.45 10.0 0.0 1.8 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.17 OAJ04639.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PIN_4 PF13638.1 OAJ04640.1 - 2e-05 24.6 0.0 7.8e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 PIN domain Imm1 PF14430.1 OAJ04640.1 - 0.073 13.2 0.2 0.53 10.4 0.1 2.1 2 0 0 2 2 2 0 Immunity protein Imm1 FAD_binding_6 PF00970.19 OAJ04642.1 - 8.6e-31 106.0 0.0 1.4e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 OAJ04642.1 - 1.7e-28 99.3 0.0 3.1e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 OAJ04642.1 - 6.1e-07 29.4 0.0 4.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 OAJ04642.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain PIF1 PF05970.9 OAJ04643.1 - 1.1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04643.1 - 7.9e-09 35.3 0.0 2.3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ04643.1 - 5.8e-05 22.7 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 OAJ04643.1 - 0.00077 18.6 0.0 0.0018 17.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 OAJ04643.1 - 0.0085 16.2 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ04643.1 - 0.091 12.4 0.8 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ICMT PF04140.9 OAJ04644.1 - 6.7e-27 93.5 0.1 1.2e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 OAJ04644.1 - 8.7e-13 48.2 1.2 8.7e-13 48.2 0.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 OAJ04644.1 - 0.00017 20.9 0.1 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 OAJ04644.1 - 0.017 13.7 0.2 0.03 12.8 0.1 1.4 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.6 OAJ04644.1 - 0.02 14.2 0.5 0.02 14.2 0.3 2.1 2 1 0 2 2 2 0 NnrU protein RRP7 PF12923.2 OAJ04645.1 - 0.14 12.1 0.9 0.32 11.0 0.6 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) GFO_IDH_MocA PF01408.17 OAJ04646.1 - 6.9e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 OAJ04646.1 - 2.2e-12 46.7 0.0 5.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 OAJ04646.1 - 0.031 14.5 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CRAL_TRIO_2 PF13716.1 OAJ04647.1 - 1e-30 106.5 0.0 2.2e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 OAJ04647.1 - 4.2e-25 88.1 0.0 6.9e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Nucleoplasmin PF03066.10 OAJ04647.1 - 0.0011 18.4 0.3 0.0026 17.2 0.2 1.6 1 0 0 1 1 1 1 Nucleoplasmin Mito_carr PF00153.22 OAJ04648.1 - 1.1e-54 182.0 0.3 5.7e-20 70.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Clat_adaptor_s PF01217.15 OAJ04649.1 - 8.8e-54 181.0 1.2 9.6e-54 180.9 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Polysacc_deac_1 PF01522.16 OAJ04650.1 - 0.0071 15.9 0.2 0.045 13.3 0.1 2.4 1 1 0 1 1 1 1 Polysaccharide deacetylase Muskelin_N PF06588.6 OAJ04651.1 - 8.9e-44 149.5 0.0 2.4e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_5 PF13854.1 OAJ04651.1 - 6.4e-12 45.1 5.7 0.0041 17.0 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 OAJ04651.1 - 1.4e-11 44.0 4.4 0.027 14.6 0.0 7.0 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.1 OAJ04651.1 - 3.4e-11 42.9 23.6 6.5e-06 26.1 0.4 8.3 9 1 0 9 9 9 3 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ04651.1 - 6.7e-08 31.9 5.6 0.00015 21.2 0.1 4.6 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 OAJ04651.1 - 3.9e-07 29.7 16.2 8.2e-05 22.2 0.1 6.8 7 1 0 7 7 7 2 Galactose oxidase, central domain Sad1_UNC PF07738.8 OAJ04651.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Kelch_2 PF07646.10 OAJ04651.1 - 0.23 11.2 12.1 0.73 9.6 0.1 5.5 6 0 0 6 6 6 0 Kelch motif DNA_repr_REX1B PF14966.1 OAJ04657.1 - 0.0068 16.7 1.3 9.2 6.7 0.1 3.8 3 1 0 3 3 3 1 DNA repair REX1-B Med17 PF10156.4 OAJ04657.1 - 0.1 10.8 3.0 0.13 10.5 0.6 1.7 1 1 1 2 2 2 0 Subunit 17 of Mediator complex GLYCAM-1 PF05242.6 OAJ04657.1 - 0.24 11.2 2.9 0.53 10.1 2.0 1.6 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Phage_Mu_Gam PF07352.7 OAJ04657.1 - 1.6 8.2 5.1 3.4 7.1 2.2 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein CSTF2_hinge PF14327.1 OAJ04658.1 - 1.2e-26 92.5 5.6 3e-26 91.3 3.9 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 OAJ04658.1 - 2.5e-22 78.2 0.0 3.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04658.1 - 1.9e-15 56.5 0.0 4.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 OAJ04658.1 - 2.2e-12 46.0 2.8 2.2e-12 46.0 1.9 2.4 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 OAJ04658.1 - 4.7e-08 32.7 0.0 7.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_25 PF13481.1 OAJ04659.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2348 PF09807.4 OAJ04659.1 - 0.00018 20.7 0.0 0.00048 19.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2348) Ser_hydrolase PF06821.8 OAJ04659.1 - 0.024 14.2 0.2 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Methyltransf_10 PF05971.7 OAJ04660.1 - 2.4e-54 184.5 0.0 9.6e-32 110.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 OAJ04660.1 - 0.00034 21.1 0.0 0.0019 18.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ04660.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ04660.1 - 0.0048 16.9 0.0 0.015 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ04660.1 - 0.015 15.7 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain B3_4 PF03483.12 OAJ04661.1 - 2.1e-27 95.7 0.0 3.8e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 OAJ04661.1 - 1.4e-19 69.6 0.0 2.3e-16 59.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain RAP1 PF07218.6 OAJ04661.1 - 1.3 7.0 4.3 1.8 6.5 3.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Slu7 PF11708.3 OAJ04662.1 - 5.2e-80 268.6 20.3 5.2e-80 268.6 14.1 2.7 2 2 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor CPSF_A PF03178.10 OAJ04663.1 - 1.6e-47 162.1 0.0 2.5e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 OAJ04663.1 - 3.8e-20 71.5 0.0 6.6e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Zn_clus PF00172.13 OAJ04664.1 - 1.4e-06 28.1 9.3 2.3e-06 27.3 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 OAJ04664.1 - 0.043 12.6 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sec1 PF00995.18 OAJ04664.1 - 0.27 9.7 0.1 0.4 9.2 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Mod_r PF07200.8 OAJ04665.1 - 1.2e-14 54.4 4.4 4.1e-10 39.7 3.0 2.1 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein FlgN PF05130.7 OAJ04665.1 - 0.00099 19.3 1.9 0.00099 19.3 1.3 2.1 1 1 1 2 2 2 1 FlgN protein Herpes_UL14 PF03580.9 OAJ04665.1 - 0.011 15.5 1.3 0.032 14.0 0.7 1.9 1 1 0 1 1 1 0 Herpesvirus UL14-like protein KfrA_N PF11740.3 OAJ04665.1 - 0.049 14.0 10.9 0.13 12.7 5.9 2.2 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term FUSC PF04632.7 OAJ04665.1 - 1 7.7 6.1 1.1 7.6 4.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box-like PF12937.2 OAJ04666.1 - 0.0054 16.4 0.4 0.013 15.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like FAM178 PF14816.1 OAJ04666.1 - 0.045 12.4 0.3 0.077 11.6 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 Abhydrolase_3 PF07859.8 OAJ04667.1 - 1.1e-48 165.6 0.1 2.2e-48 164.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 OAJ04667.1 - 2.3e-13 49.5 0.0 4.8e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) PBP1_TM PF14812.1 OAJ04667.1 - 0.12 12.6 1.6 0.42 10.9 1.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ04667.1 - 0.52 9.8 5.0 1 8.8 3.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin PCI_Csn8 PF10075.4 OAJ04668.1 - 2.8e-26 92.0 0.0 5.2e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAJ04668.1 - 3e-25 88.9 0.0 4.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family NUDIX PF00293.23 OAJ04669.1 - 5.2e-27 94.1 0.0 8.8e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF382 PF04037.8 OAJ04672.1 - 5.1e-56 188.0 0.1 9.1e-56 187.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 OAJ04672.1 - 1.8e-20 72.0 6.1 4.8e-20 70.6 4.3 1.8 1 0 0 1 1 1 1 PSP PBP1_TM PF14812.1 OAJ04672.1 - 3.7 7.9 22.1 4.5 7.6 1.0 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC50 PF03381.10 OAJ04673.1 - 1.2e-87 293.6 0.0 1.5e-87 293.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pertus-S4-tox PF09275.5 OAJ04673.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Pertussis toxin S4 subunit Aldedh PF00171.17 OAJ04675.1 - 1.3e-142 475.3 0.0 1.5e-142 475.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAGK_cat PF00781.19 OAJ04676.1 - 4.8e-12 45.4 0.1 8.2e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain zf-RING_2 PF13639.1 OAJ04678.1 - 2.5e-11 43.2 4.0 1.1e-09 38.0 1.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ04678.1 - 8.4e-09 35.4 1.6 1.5e-07 31.4 0.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ04678.1 - 2.1e-05 24.0 2.8 3.6e-05 23.3 0.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ04678.1 - 2.6e-05 23.9 0.2 6.3e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 OAJ04678.1 - 8.8e-05 22.4 2.5 8.8e-05 22.4 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ04678.1 - 9.6e-05 21.9 4.0 9.9e-05 21.9 0.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ04678.1 - 0.00077 19.1 1.2 0.00077 19.1 0.8 1.6 2 0 0 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 OAJ04678.1 - 0.11 12.5 1.7 0.57 10.1 0.5 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain AsnC_trans_reg PF01037.16 OAJ04678.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AsnC family zf-RING_UBOX PF13445.1 OAJ04678.1 - 0.39 10.4 5.9 0.058 13.1 0.3 2.4 3 0 0 3 3 3 0 RING-type zinc-finger Spore_coat_CotO PF14153.1 OAJ04679.1 - 1.6 8.1 12.9 2.5 7.4 8.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 OAJ04679.1 - 8.3 4.7 19.1 13 4.1 13.2 1.3 1 0 0 1 1 1 0 Daxx Family SIS PF01380.17 OAJ04680.1 - 2.8e-61 204.8 0.1 3.1e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 OAJ04680.1 - 3.3e-29 101.7 0.0 3.8e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 OAJ04680.1 - 3.1e-18 66.0 0.0 6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 OAJ04680.1 - 5.6e-13 48.7 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 OAJ04680.1 - 9.1e-07 27.8 0.0 1.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 OAJ04680.1 - 0.00087 19.0 0.0 0.05 13.3 0.0 3.2 3 1 1 4 4 4 1 SIS domain Plasmid_Txe PF06769.8 OAJ04680.1 - 0.15 11.9 0.0 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 Plasmid encoded toxin Txe Actin PF00022.14 OAJ04682.1 - 5.3e-92 308.2 0.0 6.6e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Actin Chitin_synth_2 PF03142.10 OAJ04683.1 - 5.3e-240 797.3 0.2 5.3e-240 797.3 0.2 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 OAJ04683.1 - 2e-153 512.0 0.0 2.7e-153 511.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 OAJ04683.1 - 1.1e-17 64.4 2.0 1.1e-17 64.4 1.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ04683.1 - 5.2e-15 55.8 0.0 1.5e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 OAJ04683.1 - 4.2e-14 52.0 0.0 3.7e-06 26.6 0.0 3.0 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 OAJ04683.1 - 9.3e-14 50.9 1.4 1.2e-11 44.1 0.0 4.0 4 0 0 4 4 4 1 DEK C terminal domain Glycos_transf_2 PF00535.21 OAJ04683.1 - 4.9e-05 23.0 0.0 0.0043 16.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ04683.1 - 0.0044 16.3 0.0 0.051 12.8 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 21 AAA_16 PF13191.1 OAJ04683.1 - 0.053 13.5 0.0 0.21 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 OAJ04683.1 - 0.17 10.9 0.0 0.38 9.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 OAJ04683.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APC10 PF03256.11 OAJ04684.1 - 1.1e-42 145.8 0.0 1.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF688 PF05097.7 OAJ04684.1 - 0.43 9.4 1.9 0.48 9.3 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF688) Enolase_C PF00113.17 OAJ04685.1 - 3.2e-142 472.8 0.1 4.1e-142 472.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 OAJ04685.1 - 5.8e-57 191.2 0.1 9.5e-57 190.5 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 OAJ04685.1 - 7.7e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 OAJ04685.1 - 0.0082 15.0 0.1 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 OAJ04685.1 - 0.059 13.8 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain WD40 PF00400.27 OAJ04686.1 - 5.3e-75 244.8 14.5 1.3e-12 47.0 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ04686.1 - 2.7e-10 39.0 16.4 0.0012 17.0 0.1 5.4 2 1 4 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ04686.1 - 2e-05 23.5 2.4 1.7 7.2 0.1 4.4 1 1 4 5 5 5 3 Nup133 N terminal like eIF2A PF08662.6 OAJ04686.1 - 0.028 14.1 0.0 3.3 7.3 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Apolipoprotein PF01442.13 OAJ04687.1 - 0.094 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PBP PF01161.15 OAJ04688.1 - 2.9e-20 72.5 0.3 2.9e-20 72.5 0.2 1.7 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein DUF3366 PF11846.3 OAJ04688.1 - 0.24 11.2 1.1 0.41 10.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) zf-RING_2 PF13639.1 OAJ04689.1 - 2.5e-08 33.5 12.4 4.1e-08 32.9 8.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ04689.1 - 1.3e-05 25.2 3.4 2.2e-05 24.4 2.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ04689.1 - 1.6e-05 24.4 9.7 2.7e-05 23.7 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ04689.1 - 0.00032 20.6 12.8 0.00052 19.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ04689.1 - 0.00043 19.9 11.1 0.00064 19.3 7.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain HHV6-IE PF03753.8 OAJ04689.1 - 0.95 6.8 4.2 0.3 8.5 0.7 1.6 2 0 0 2 2 2 0 Human herpesvirus 6 immediate early protein zf-C3HC4 PF00097.20 OAJ04689.1 - 1.5 8.5 11.7 2.3 7.9 8.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rep_fac-A_C PF08646.5 OAJ04690.1 - 6.1e-55 184.9 1.8 1.4e-53 180.5 0.5 2.6 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 OAJ04690.1 - 2e-25 88.5 0.0 4.2e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 OAJ04690.1 - 4.8e-13 48.7 0.3 3e-11 43.0 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 OAJ04690.1 - 0.0011 19.0 0.2 0.021 14.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF223 Thioredoxin_4 PF13462.1 OAJ04691.1 - 1.9e-07 31.2 0.0 6.8e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin TctC PF03401.9 OAJ04691.1 - 0.075 11.9 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Elongin_A PF06881.6 OAJ04692.1 - 3.1e-26 91.8 0.4 4.7e-26 91.3 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3371 PF11851.3 OAJ04692.1 - 0.1 13.2 3.8 0.14 12.7 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Apolipoprotein PF01442.13 OAJ04703.1 - 4e-05 23.2 0.6 4.7e-05 22.9 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain AIP3 PF03915.8 OAJ04703.1 - 0.00021 20.3 1.5 0.00024 20.1 1.1 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Mer2 PF09074.5 OAJ04703.1 - 0.0035 17.2 0.2 0.0045 16.9 0.1 1.1 1 0 0 1 1 1 1 Mer2 Sds3 PF08598.6 OAJ04703.1 - 0.004 16.7 3.4 0.0051 16.3 2.3 1.1 1 0 0 1 1 1 1 Sds3-like DUF793 PF05633.6 OAJ04703.1 - 0.011 14.5 0.4 0.014 14.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Syntaxin PF00804.20 OAJ04703.1 - 0.016 15.3 0.6 0.021 14.9 0.4 1.2 1 0 0 1 1 1 0 Syntaxin DUF883 PF05957.8 OAJ04703.1 - 0.029 14.7 7.1 0.11 12.8 2.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Blo-t-5 PF11642.3 OAJ04703.1 - 0.038 13.7 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 DUF1789 PF08748.6 OAJ04703.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) ISG65-75 PF11727.3 OAJ04703.1 - 0.1 11.6 0.4 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein PIF1 PF05970.9 OAJ04704.1 - 1.1e-19 70.6 0.0 2.4e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04704.1 - 8.4e-12 45.0 0.0 8.4e-12 45.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 OAJ04704.1 - 6.5e-08 32.2 0.5 2.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ04704.1 - 4.9e-07 29.6 0.1 2e-06 27.6 0.0 2.2 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ04704.1 - 0.00042 20.3 0.1 0.002 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 OAJ04704.1 - 0.096 12.4 0.2 0.42 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAJ04704.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2972 PF11186.3 OAJ04704.1 - 0.85 9.4 0.1 1.6 8.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Nucleoplasmin PF03066.10 OAJ04705.1 - 6.7 6.2 15.2 5.6 6.4 0.7 2.3 2 0 0 2 2 2 0 Nucleoplasmin Zn-ribbon_8 PF09723.5 OAJ04706.1 - 0.18 11.8 1.7 7.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrom_B558a PF05038.8 OAJ04706.1 - 5 6.7 5.3 1.5 8.4 0.2 2.0 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Ufd2P_core PF10408.4 OAJ04708.1 - 1.6e-179 598.1 0.0 2e-179 597.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 OAJ04708.1 - 2.8e-26 91.2 0.3 7.4e-26 89.9 0.2 1.8 1 0 0 1 1 1 1 U-box domain cobW PF02492.14 OAJ04709.1 - 3.1e-33 114.7 0.0 4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 OAJ04709.1 - 0.00011 21.0 1.9 0.00034 19.4 1.3 1.6 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 OAJ04709.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 OAJ04709.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 OAJ04709.1 - 0.02 15.6 0.0 0.036 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ04709.1 - 0.052 13.3 0.1 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 OAJ04709.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 OAJ04709.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 OAJ04709.1 - 0.13 12.2 0.0 0.67 9.9 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 OAJ04709.1 - 0.14 11.0 0.0 0.29 10.0 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 OAJ04709.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 OAJ04709.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain SelP_N PF04592.9 OAJ04709.1 - 0.66 9.3 14.7 0.95 8.7 10.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 OAJ04709.1 - 1.3 7.9 10.2 1.8 7.4 7.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 OAJ04709.1 - 2.5 6.8 17.6 3.4 6.4 12.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Acyl-CoA_dh_1 PF00441.19 OAJ04710.1 - 8.6e-28 97.3 2.1 1.3e-27 96.7 1.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ04710.1 - 3.6e-14 53.1 2.5 3.6e-14 53.1 1.7 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ04710.1 - 1.2e-13 50.3 0.0 3.1e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ04710.1 - 6.9e-10 39.4 0.0 1.3e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 OAJ04710.1 - 0.096 12.0 0.0 1.6 8.0 0.0 2.4 2 1 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ten1_2 PF15490.1 OAJ04711.1 - 5e-06 26.0 0.0 2.7e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit TPP_enzyme_C PF02775.16 OAJ04713.1 - 1.4e-15 57.1 0.0 2.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 OAJ04713.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component SKN1 PF03935.10 OAJ04714.1 - 1.4e-169 564.5 0.0 2.2e-169 563.8 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Abhydrolase_6 PF12697.2 OAJ04715.1 - 6.9e-29 101.3 0.7 1.3e-28 100.4 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ04715.1 - 4.7e-11 42.6 0.1 0.0051 16.4 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ04715.1 - 5.7e-10 39.1 0.0 2e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ04715.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Glyoxalase_2 PF12681.2 OAJ04717.1 - 4.5e-11 43.3 0.0 5.4e-10 39.8 0.0 2.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 OAJ04717.1 - 4e-05 23.5 0.0 0.00043 20.2 0.0 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CPSase_L_D2 PF02786.12 OAJ04718.1 - 5.4e-83 277.4 0.1 9.2e-83 276.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 OAJ04718.1 - 3.4e-69 232.2 0.0 7.7e-69 231.0 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 OAJ04718.1 - 1.7e-36 124.6 0.3 8.9e-36 122.3 0.0 2.5 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 OAJ04718.1 - 7.7e-31 106.2 0.0 1.8e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 OAJ04718.1 - 4.7e-29 101.7 0.0 9.3e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 OAJ04718.1 - 8.6e-19 67.9 0.2 1.5e-18 67.1 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ04718.1 - 8.4e-17 60.9 0.0 3.6e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 OAJ04718.1 - 1.2e-16 60.1 0.8 2.3e-16 59.1 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 OAJ04718.1 - 1.9e-14 53.0 0.5 4.7e-06 26.1 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 OAJ04718.1 - 2.8e-11 43.1 0.0 5.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 OAJ04718.1 - 2.2e-09 37.0 0.3 0.00074 18.9 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 OAJ04718.1 - 1.5e-07 30.9 0.0 3.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 OAJ04718.1 - 4.8e-06 26.1 0.0 1.4e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 OAJ04718.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 OAJ04718.1 - 0.00057 20.1 0.2 0.97 9.8 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 OAJ04718.1 - 0.0066 15.6 0.2 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.14 OAJ04718.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_2 PF12700.2 OAJ04718.1 - 0.013 14.6 0.1 0.32 10.1 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 OAJ04718.1 - 0.12 12.0 1.6 1.1 8.9 0.3 2.8 2 1 1 3 3 3 0 Glycine cleavage H-protein SAE2 PF08573.5 OAJ04719.1 - 3.5e-12 46.8 4.5 4.7e-11 43.2 0.1 3.6 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SATase_N PF06426.9 OAJ04719.1 - 0.031 14.5 2.0 1.4 9.2 0.1 2.7 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal PhoU_div PF01865.11 OAJ04719.1 - 0.085 12.0 0.1 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 RNA_Me_trans PF04252.8 OAJ04720.1 - 4.2e-19 68.7 0.0 1.2e-15 57.4 0.0 2.9 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DDE_1 PF03184.14 OAJ04721.1 - 3.2e-80 268.3 0.6 4.5e-40 137.0 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 OAJ04721.1 - 8e-12 44.7 0.0 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Auxin_BP PF02041.11 OAJ04721.1 - 0.092 12.1 1.4 9.5 5.6 0.1 2.4 2 0 0 2 2 2 0 Auxin binding protein Rad51 PF08423.6 OAJ04723.1 - 3.2e-09 36.0 0.0 5.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 OAJ04723.1 - 1.6e-08 34.2 0.2 7.4e-08 32.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain RecA PF00154.16 OAJ04723.1 - 2.5e-06 26.7 0.0 4.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 OAJ04723.1 - 4.4e-05 22.7 0.1 0.00011 21.4 0.0 1.6 2 0 0 2 2 2 1 KaiC PAXNEB PF05625.6 OAJ04723.1 - 0.11 11.3 0.5 0.32 9.7 0.1 1.9 2 0 0 2 2 2 0 PAXNEB protein L51_S25_CI-B8 PF05047.11 OAJ04724.1 - 6e-10 38.7 0.1 9.2e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HSP20 PF00011.16 OAJ04726.1 - 6.7e-18 64.4 0.5 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family TAF8_C PF10406.4 OAJ04727.1 - 0.051 13.6 0.1 0.48 10.5 0.0 2.7 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term PEX11 PF05648.9 OAJ04728.1 - 1.2e-14 54.1 0.0 2.1e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNARE PF05739.14 OAJ04729.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 OAJ04729.1 - 0.012 15.0 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Pkinase PF00069.20 OAJ04730.1 - 1.5e-73 247.1 0.0 2e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04730.1 - 7.5e-36 123.5 0.0 1.1e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04730.1 - 0.00075 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ETC_C1_NDUFA5 PF04716.9 OAJ04731.1 - 2.2e-16 59.1 0.2 3.4e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region zf-C2H2 PF00096.21 OAJ04732.1 - 0.00024 21.2 14.4 0.0084 16.3 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ04732.1 - 0.00028 20.9 14.5 0.027 14.8 2.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ04732.1 - 0.32 11.3 3.7 9.3 6.7 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.20 OAJ04733.1 - 6.7e-60 202.4 0.7 1.2e-41 142.5 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04733.1 - 6.9e-26 90.8 0.1 7.9e-20 71.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04733.1 - 0.00082 18.4 0.0 0.00082 18.4 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Pox_ser-thr_kin PF05445.6 OAJ04733.1 - 0.065 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 OAJ04733.1 - 0.088 12.5 0.0 0.088 12.5 0.0 3.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 OAJ04733.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Hid1 PF12722.2 OAJ04733.1 - 2 6.0 3.7 3 5.4 2.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RHH_4 PF13467.1 OAJ04734.1 - 0.024 14.5 1.3 0.043 13.6 0.9 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Amidohydro_2 PF04909.9 OAJ04735.1 - 0.00041 20.0 0.0 0.0029 17.2 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase MreC PF04085.9 OAJ04735.1 - 0.041 13.3 0.1 0.072 12.5 0.1 1.3 1 0 0 1 1 1 0 rod shape-determining protein MreC Ribophorin_II PF05817.9 OAJ04737.1 - 9e-07 27.4 1.2 1.5e-06 26.7 0.8 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II GCR1_C PF12550.3 OAJ04738.1 - 2.4e-21 75.4 0.2 4.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes RIC1 PF07064.8 OAJ04739.1 - 3.4e-69 233.1 1.8 5.7e-66 222.6 0.8 3.1 2 1 0 2 2 2 2 RIC1 V-ATPase_H_N PF03224.9 OAJ04744.1 - 6.5e-83 278.4 0.0 1.4e-82 277.3 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 OAJ04744.1 - 5.2e-31 107.0 0.0 1.8e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.17 OAJ04744.1 - 0.0085 16.0 0.0 0.54 10.4 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat SMC_N PF02463.14 OAJ04745.1 - 5.7e-26 91.1 2.2 1.5e-25 89.7 1.5 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ04745.1 - 2.8e-06 27.7 44.6 2.8e-06 27.7 30.9 5.9 3 2 0 3 3 3 1 AAA domain AAA_13 PF13166.1 OAJ04745.1 - 3.8e-06 25.6 71.8 0.0088 14.5 6.2 5.4 3 2 2 5 5 5 5 AAA domain AAA_21 PF13304.1 OAJ04745.1 - 1.2e-05 25.4 0.8 0.13 12.2 0.3 3.4 2 1 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 OAJ04745.1 - 7.6e-05 22.0 13.3 0.041 13.0 0.0 5.2 3 2 2 6 6 6 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 OAJ04745.1 - 0.00065 19.5 0.0 0.0024 17.7 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 OAJ04745.1 - 0.0014 18.1 0.2 0.0033 16.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HLH PF00010.21 OAJ04746.1 - 4.2e-05 23.1 0.0 9.4e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain RAB3GAP2_N PF14655.1 OAJ04746.1 - 1.4 7.8 8.4 4 6.3 0.1 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 OAJ04746.1 - 5.3 5.1 53.9 0.93 7.6 21.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp PF00026.18 OAJ04747.1 - 1.6e-50 172.1 6.0 5.1e-50 170.5 4.2 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 OAJ04747.1 - 0.00083 18.9 0.0 0.0033 16.9 0.0 2.0 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 OAJ04747.1 - 0.00094 19.6 1.1 0.038 14.4 0.5 2.4 2 0 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 OAJ04747.1 - 0.0015 18.4 5.2 0.019 14.9 2.5 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal OEP PF02321.13 OAJ04748.1 - 0.029 13.9 0.3 0.029 13.9 0.2 2.0 1 1 1 2 2 2 0 Outer membrane efflux protein Metal_resist PF13801.1 OAJ04748.1 - 0.055 13.4 5.4 0.15 12.0 0.9 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Y_phosphatase PF00102.22 OAJ04749.1 - 9.6e-54 182.1 0.2 2.6e-46 157.8 0.0 2.9 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 OAJ04749.1 - 6.9e-05 23.1 0.0 0.00035 20.8 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 OAJ04749.1 - 0.0074 16.5 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 OAJ04749.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Asp PF00026.18 OAJ04750.1 - 1.6e-49 168.9 0.7 4.8e-49 167.3 0.5 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ04750.1 - 0.00032 20.6 2.1 0.003 17.5 1.5 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ04750.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal SBP_bac_11 PF13531.1 OAJ04751.1 - 0.0052 16.4 0.5 0.0059 16.2 0.4 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein PLDc PF00614.17 OAJ04752.1 - 9.3e-15 53.8 1.4 5.2e-08 32.4 0.4 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAJ04752.1 - 1.2e-14 54.1 0.0 2.2e-07 30.6 0.0 3.7 3 1 0 3 3 3 2 PLD-like domain Pyridoxal_deC PF00282.14 OAJ04754.1 - 7.7e-106 353.6 0.0 8.7e-105 350.2 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ04754.1 - 0.0018 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ04754.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ04754.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V PI3_PI4_kinase PF00454.22 OAJ04755.1 - 1.2e-44 152.6 0.0 1.9e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 OAJ04755.1 - 2e-25 89.3 0.2 2e-25 89.3 0.2 3.1 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 OAJ04755.1 - 2.4e-08 33.2 0.0 7.1e-08 31.7 0.0 1.9 1 0 0 1 1 1 1 FATC domain Pyridoxal_deC PF00282.14 OAJ04756.1 - 1e-101 340.1 0.0 6.3e-100 334.2 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 OAJ04756.1 - 0.0088 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cyclin PF08613.6 OAJ04759.1 - 6e-34 117.6 5.7 4.3e-22 79.1 0.0 2.8 3 1 0 3 3 3 2 Cyclin DUF659 PF04937.10 OAJ04760.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 OAJ04760.1 - 0.00032 20.2 0.0 0.00082 18.9 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FPN1 PF06963.7 OAJ04761.1 - 5.6e-121 403.9 3.9 4.4e-104 348.2 1.8 2.0 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Anoctamin PF04547.7 OAJ04762.1 - 1.1e-96 324.2 0.0 1.4e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel FMO-like PF00743.14 OAJ04764.1 - 1.3e-19 69.7 0.0 8.5e-14 50.6 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ04764.1 - 3.5e-13 50.0 0.0 4e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ04764.1 - 7.6e-05 21.7 0.0 0.0091 14.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ04764.1 - 0.00015 21.6 2.4 0.00045 20.0 0.1 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ04764.1 - 0.00021 21.2 0.0 0.0005 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ04764.1 - 0.00049 20.0 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAJ04764.1 - 0.0057 16.7 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ04764.1 - 0.1 12.8 0.1 2.9 8.1 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding PRP38 PF03371.10 OAJ04765.1 - 9.2e-62 207.6 0.1 1.2e-61 207.3 0.1 1.1 1 0 0 1 1 1 1 PRP38 family Metal_resist PF13801.1 OAJ04765.1 - 0.024 14.6 5.0 0.049 13.6 3.5 1.5 1 0 0 1 1 1 0 Heavy-metal resistance HpcH_HpaI PF03328.9 OAJ04767.1 - 9.7e-37 125.9 0.1 2.1e-36 124.8 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 OAJ04767.1 - 7.4e-09 34.8 0.0 0.0002 20.3 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold ABC_tran PF00005.22 OAJ04768.1 - 3.6e-33 114.7 0.0 7.7e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 OAJ04768.1 - 8.3e-29 100.8 3.3 1.7e-28 99.7 2.3 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 OAJ04768.1 - 1.2e-06 28.7 0.0 0.00012 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 OAJ04768.1 - 2.1e-05 23.8 0.1 0.00058 19.1 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 OAJ04768.1 - 9.2e-05 22.5 0.6 0.00027 20.9 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 OAJ04768.1 - 0.00023 20.3 0.0 0.00046 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 OAJ04768.1 - 0.0011 19.1 0.1 0.0051 16.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 OAJ04768.1 - 0.0023 17.5 3.9 0.14 11.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ04768.1 - 0.028 13.4 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 OAJ04768.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3595 PF12166.3 OAJ04768.1 - 0.13 11.0 3.8 2.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) RNA_pol_Rpc4 PF05132.9 OAJ04769.1 - 8.4e-20 71.0 2.6 8.4e-20 71.0 1.8 3.6 3 1 0 3 3 3 1 RNA polymerase III RPC4 Leo1 PF04004.8 OAJ04769.1 - 0.0059 16.3 0.2 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Leo1-like protein Rpr2 PF04032.11 OAJ04770.1 - 3.7e-12 45.9 0.1 5.5e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 OAJ04770.1 - 0.075 12.8 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon RAP1 PF07218.6 OAJ04771.1 - 3.4 5.6 6.6 6.1 4.8 4.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Arv1 PF04161.8 OAJ04772.1 - 6.2e-19 68.7 3.5 1.8e-15 57.4 0.1 2.2 2 0 0 2 2 2 2 Arv1-like family ABM PF03992.11 OAJ04773.1 - 0.0029 17.6 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase IF-2B PF01008.12 OAJ04774.1 - 2.6e-67 226.7 0.0 3.7e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family PAT1 PF09770.4 OAJ04774.1 - 7.2 4.7 38.7 8.9 4.4 26.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 OAJ04774.1 - 9.1 6.5 20.2 15 5.8 14.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PgaD PF13994.1 OAJ04775.1 - 0.00073 19.0 0.2 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 PgaD-like protein DUF3188 PF11384.3 OAJ04775.1 - 0.011 15.2 2.6 0.025 14.1 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) CcmH PF03918.9 OAJ04775.1 - 0.14 11.1 0.1 0.3 10.0 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein IncA PF04156.9 OAJ04775.1 - 0.14 11.7 0.8 0.58 9.7 0.5 2.0 1 1 0 1 1 1 0 IncA protein DUF4381 PF14316.1 OAJ04775.1 - 0.43 10.6 1.3 1.1 9.3 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Aminotran_1_2 PF00155.16 OAJ04776.1 - 2.2e-32 112.4 0.0 2.7e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 OAJ04776.1 - 0.009 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2408 PF10303.4 OAJ04777.1 - 8.9e-53 177.9 0.3 5.5e-36 123.6 0.0 4.7 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) CDC45 PF02724.9 OAJ04777.1 - 0.019 13.0 1.7 0.034 12.1 1.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF972 PF06156.8 OAJ04777.1 - 0.17 12.2 0.2 4.6 7.6 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF972) DUF4303 PF14136.1 OAJ04778.1 - 0.21 11.2 2.0 0.25 10.9 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Actin PF00022.14 OAJ04780.1 - 6.6e-19 67.5 0.0 9.7e-11 40.6 0.0 3.3 3 1 0 3 3 3 3 Actin SAC3_GANP PF03399.11 OAJ04781.1 - 6.4e-70 234.8 1.9 8.5e-70 234.4 1.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAJ04781.1 - 0.0034 17.1 0.1 0.0085 15.8 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 YEATS PF03366.11 OAJ04782.1 - 1.3e-31 108.1 0.0 2.9e-31 107.0 0.0 1.6 1 1 0 1 1 1 1 YEATS family DUF2570 PF10828.3 OAJ04782.1 - 0.68 9.5 3.3 1.3 8.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Kinesin PF00225.18 OAJ04783.1 - 2.9e-93 312.2 0.1 9.5e-93 310.5 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF812 PF05667.6 OAJ04783.1 - 0.013 14.0 14.4 0.025 13.1 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Macoilin PF09726.4 OAJ04783.1 - 0.2 9.9 15.0 0.4 8.9 10.4 1.5 1 0 0 1 1 1 0 Transmembrane protein Filament PF00038.16 OAJ04783.1 - 3.7 6.9 25.5 0.78 9.1 8.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein Surfac_D-trimer PF09006.6 OAJ04783.1 - 4.1 7.2 5.2 4.4 7.1 2.4 2.0 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF3099 PF11298.3 OAJ04786.1 - 0.059 13.1 0.8 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) V-SNARE_C PF12352.3 OAJ04787.1 - 2e-17 63.0 7.3 3.4e-17 62.2 4.3 2.0 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 OAJ04787.1 - 2e-15 56.6 1.9 2e-15 56.6 1.3 2.9 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Prominin PF05478.6 OAJ04787.1 - 0.023 12.2 0.7 0.068 10.7 0.0 1.8 2 0 0 2 2 2 0 Prominin Fusion_gly PF00523.13 OAJ04787.1 - 0.023 12.7 0.1 0.023 12.7 0.1 1.7 2 0 0 2 2 2 0 Fusion glycoprotein F0 PNK3P PF08645.6 OAJ04787.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase YqjK PF13997.1 OAJ04787.1 - 0.048 13.8 1.5 0.1 12.7 0.4 2.1 2 0 0 2 2 2 0 YqjK-like protein ApoLp-III PF07464.6 OAJ04787.1 - 0.058 13.4 8.7 1.6 8.6 0.1 2.9 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Sec20 PF03908.8 OAJ04787.1 - 0.073 12.7 2.0 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 Sec20 Sec8_exocyst PF04048.9 OAJ04787.1 - 0.12 12.0 1.3 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF912 PF06024.7 OAJ04787.1 - 0.19 11.8 1.4 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sigma_reg_N PF13800.1 OAJ04787.1 - 0.35 10.9 3.1 0.6 10.1 2.1 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Fib_alpha PF08702.5 OAJ04787.1 - 1.9 8.6 4.6 3.4 7.7 1.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RmuC PF02646.11 OAJ04787.1 - 9 5.0 10.2 0.77 8.5 0.2 2.8 2 1 0 3 3 3 0 RmuC family Gryzun PF07919.7 OAJ04789.1 - 8.1e-26 90.4 0.0 6.4e-19 67.6 0.0 2.4 2 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 OAJ04789.1 - 2.6e-14 53.3 0.0 2.9e-13 49.8 0.0 2.6 1 1 0 1 1 1 1 Foie gras liver health family 1 Aconitase PF00330.15 OAJ04790.1 - 5.9e-151 503.0 0.0 1.1e-150 502.2 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ04790.1 - 7.6e-32 110.1 0.0 1.6e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.4 OAJ04790.1 - 0.0024 17.7 1.6 0.02 14.6 1.2 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 OsmC PF02566.14 OAJ04790.1 - 0.062 13.4 0.6 1.9 8.7 0.0 2.9 2 0 0 2 2 2 0 OsmC-like protein GalKase_gal_bdg PF10509.4 OAJ04791.1 - 4.3e-20 70.7 0.0 9.3e-20 69.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 OAJ04791.1 - 3.5e-12 46.2 1.2 3.5e-12 46.2 0.8 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 OAJ04791.1 - 2.9e-11 43.3 0.0 8e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal PPTA PF01239.17 OAJ04792.1 - 3.4e-41 136.8 18.8 3.4e-09 35.6 0.1 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Carn_acyltransf PF00755.15 OAJ04794.1 - 9.2e-152 506.1 0.0 1.3e-151 505.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rho_GDI PF02115.12 OAJ04795.1 - 4.3e-50 169.9 0.0 5.2e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Glucan_synthase PF02364.10 OAJ04796.1 - 1.2e-165 552.6 12.0 1.3e-165 552.5 8.3 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.10 OAJ04797.1 - 3.5e-207 690.0 0.0 3.9e-207 689.9 0.0 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.10 OAJ04798.1 - 4.4e-114 382.1 0.1 6.4e-114 381.5 0.1 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 OAJ04798.1 - 7.5e-38 129.0 0.0 1.7e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Filament PF00038.16 OAJ04799.1 - 0.0026 17.2 43.3 0.0026 17.2 30.0 4.7 1 1 3 4 4 4 2 Intermediate filament protein Cep57_CLD_2 PF14197.1 OAJ04799.1 - 0.008 16.0 11.3 0.008 16.0 7.8 8.1 5 2 2 7 7 7 1 Centrosome localisation domain of PPC89 STT3 PF02516.9 OAJ04800.1 - 3.3e-134 448.4 34.9 2.5e-132 442.2 24.2 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DUF1978 PF09321.5 OAJ04800.1 - 0.2 11.0 0.1 0.3 10.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) RhoGAP PF00620.22 OAJ04801.1 - 2.2e-37 128.0 0.0 5.2e-37 126.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain TRAUB PF08164.7 OAJ04801.1 - 0.038 14.0 0.2 0.11 12.6 0.2 1.8 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal CTV_P6 PF06706.6 OAJ04802.1 - 0.77 9.2 7.9 5.8 6.4 1.1 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Nop14 PF04147.7 OAJ04803.1 - 1e-05 23.7 30.5 2e-05 22.7 21.1 1.5 1 0 0 1 1 1 1 Nop14-like family DUF837 PF05769.6 OAJ04803.1 - 2.6e-05 23.8 9.4 0.00064 19.3 2.7 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF837) RTC PF01137.16 OAJ04804.1 - 4.5e-56 189.1 0.0 5.7e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 OAJ04804.1 - 1.2e-28 99.1 0.0 2.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PBP1_TM PF14812.1 OAJ04804.1 - 0.24 11.7 5.3 0.42 10.9 3.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 OAJ04804.1 - 0.74 9.6 3.8 2.6 7.8 2.1 1.9 1 1 1 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 OAJ04804.1 - 2.5 7.5 6.1 4.3 6.8 4.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 OAJ04804.1 - 3.1 7.3 6.9 2.7 7.5 3.5 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.4 OAJ04804.1 - 3.5 6.2 7.7 5.5 5.6 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Na_H_Exchanger PF00999.16 OAJ04805.1 - 4.8e-63 212.9 32.8 6.8e-63 212.4 22.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C2H2_4 PF13894.1 OAJ04805.1 - 9.6e-11 41.2 11.4 0.0012 18.9 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ04805.1 - 1.8e-10 40.4 11.4 0.0089 16.3 0.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 OAJ04805.1 - 5.8e-09 35.7 13.8 0.00075 19.6 1.8 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 OAJ04805.1 - 0.0024 18.0 4.8 0.24 11.6 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 OAJ04805.1 - 0.046 13.6 1.0 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 OAJ04805.1 - 0.093 12.9 11.0 0.098 12.8 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding OSTMP1 PF09777.4 OAJ04805.1 - 0.31 10.1 1.7 0.36 9.9 0.1 1.8 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Transposase_21 PF02992.9 OAJ04806.1 - 1.4e-05 24.3 0.0 9.4e-05 21.6 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 DUF2962 PF11176.3 OAJ04806.1 - 0.024 14.1 0.5 0.062 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2962) Ndc1_Nup PF09531.5 OAJ04807.1 - 7.6 4.8 6.5 7.9 4.7 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Adenylsucc_synt PF00709.16 OAJ04808.1 - 1e-160 535.0 0.0 1.1e-160 534.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Myco_arth_vir_N PF09610.5 OAJ04809.1 - 0.063 13.2 2.9 0.098 12.6 2.0 1.2 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Ribosomal_L7Ae PF01248.21 OAJ04810.1 - 5e-23 80.4 0.0 5.7e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L37e PF01907.14 OAJ04811.1 - 1.5e-25 88.7 12.0 2.7e-25 87.9 8.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 OAJ04811.1 - 0.0051 16.6 1.7 0.0077 16.0 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 OAJ04811.1 - 0.013 15.1 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.14 OAJ04811.1 - 0.088 12.4 0.9 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S14 PF00253.16 OAJ04811.1 - 0.097 12.0 0.6 0.097 12.0 0.4 2.5 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e zf-C3HC4 PF00097.20 OAJ04811.1 - 1.2 8.8 6.7 1.9 8.2 4.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DASH_Duo1 PF08651.5 OAJ04812.1 - 3.5e-16 58.5 0.1 5.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 EnY2 PF10163.4 OAJ04813.1 - 5.3e-13 48.6 0.0 7.6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 Ten1 PF12658.2 OAJ04813.1 - 0.09 12.5 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Telomere capping, CST complex subunit DUF2309 PF10070.4 OAJ04813.1 - 0.1 10.6 0.2 0.11 10.6 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF3526 PF12040.3 OAJ04813.1 - 0.22 11.6 1.9 10 6.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3526) Rabaptin PF03528.10 OAJ04813.1 - 0.73 9.7 8.2 0.72 9.7 2.4 2.2 1 1 1 2 2 2 0 Rabaptin Glyco_trans_1_4 PF13692.1 OAJ04814.1 - 5.5e-18 65.4 0.1 1.9e-15 57.1 0.0 3.1 3 1 1 4 4 4 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ04814.1 - 7.6e-13 48.9 7.0 2.8e-12 47.0 4.9 2.0 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 OAJ04814.1 - 2.2e-05 23.9 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ04814.1 - 0.00029 21.0 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.24 OAJ04815.1 - 5.3e-38 130.1 0.0 1.8e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ04815.1 - 2.1e-21 75.5 0.0 6e-21 74.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 OAJ04815.1 - 3.7e-17 61.8 1.9 1.1e-16 60.4 1.3 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 OAJ04815.1 - 0.0021 17.8 0.0 0.14 12.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2537 PF10801.3 OAJ04816.1 - 0.048 13.7 1.5 0.13 12.4 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Cyt-b5 PF00173.23 OAJ04817.1 - 5.4e-11 42.1 0.0 7.1e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tropomyosin_1 PF12718.2 OAJ04818.1 - 0.0024 17.7 22.2 0.0024 17.7 15.4 7.0 3 1 3 6 6 6 3 Tropomyosin like Alg6_Alg8 PF03155.10 OAJ04819.1 - 5.1e-108 361.9 13.0 2.3e-49 168.5 0.1 3.0 3 0 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.8 OAJ04819.1 - 1.2 8.2 7.3 3.6 6.7 0.3 2.6 2 1 0 3 3 3 0 ALG3 protein DUF663 PF04950.7 OAJ04820.1 - 2.1e-81 273.1 0.1 4.8e-81 271.9 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ04820.1 - 1e-28 98.6 0.0 3.1e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 OAJ04820.1 - 5.1e-06 26.5 0.1 2.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.22 OAJ04820.1 - 6.2e-06 25.7 0.0 0.00038 19.9 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ04820.1 - 4.7e-05 23.5 0.0 0.00018 21.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ04820.1 - 0.00019 21.1 0.1 0.00049 19.8 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAJ04820.1 - 0.0011 19.4 0.7 0.0036 17.7 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein NACHT PF05729.7 OAJ04820.1 - 0.0014 18.3 0.2 0.0035 17.0 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA_17 PF13207.1 OAJ04820.1 - 0.0025 18.6 0.0 0.0025 18.6 0.0 3.3 2 2 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 OAJ04820.1 - 0.0027 17.1 0.1 0.0088 15.5 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 OAJ04820.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 OAJ04820.1 - 0.01 15.7 0.1 0.037 13.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ04820.1 - 0.011 15.6 2.2 0.016 15.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 OAJ04820.1 - 0.012 15.0 0.0 0.081 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ04820.1 - 0.035 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 OAJ04820.1 - 0.04 13.8 0.1 0.15 12.0 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 OAJ04820.1 - 0.041 14.1 0.0 0.041 14.1 0.0 2.7 4 0 0 4 4 3 0 ABC transporter Arch_ATPase PF01637.13 OAJ04820.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 OAJ04820.1 - 0.064 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 OAJ04820.1 - 0.076 12.7 0.4 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 OAJ04820.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 OsmC PF02566.14 OAJ04821.1 - 2.8e-18 65.9 0.0 4.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein AAA PF00004.24 OAJ04822.1 - 0.0011 19.1 0.1 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 OAJ04822.1 - 0.049 14.4 0.1 0.049 14.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 OAJ04822.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 OAJ04822.1 - 0.46 9.1 0.0 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF2638 PF10937.3 OAJ04824.1 - 5.7e-11 43.4 2.3 7e-11 43.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) SNARE PF05739.14 OAJ04825.1 - 2.9e-08 33.2 1.4 2.9e-08 33.2 1.0 3.6 4 0 0 4 4 4 1 SNARE domain Polysacc_deac_2 PF04748.8 OAJ04825.1 - 0.013 14.4 1.4 0.087 11.8 0.0 2.4 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase DUF4211 PF13926.1 OAJ04826.1 - 8.5e-06 25.2 0.1 2.2e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) RRM_1 PF00076.17 OAJ04827.1 - 6.6e-17 60.9 0.0 1e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04827.1 - 2.7e-16 59.2 0.0 4.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ04827.1 - 7.4e-08 32.1 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI2 PF06432.6 OAJ04828.1 - 2.9e-72 243.3 4.4 2.6e-63 213.9 0.3 2.1 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Tic20 PF09685.5 OAJ04828.1 - 0.57 10.1 0.0 0.57 10.1 0.0 3.3 4 0 0 4 4 4 0 Tic20-like protein GCIP PF13324.1 OAJ04829.1 - 5.6e-05 22.4 1.1 0.00075 18.8 0.2 2.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Ribosomal_60s PF00428.14 OAJ04829.1 - 0.0017 18.7 1.3 0.0017 18.7 0.9 4.4 4 0 0 4 4 4 1 60s Acidic ribosomal protein Cyclin_N PF00134.18 OAJ04840.1 - 9.6e-25 86.6 0.0 4.9e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ04840.1 - 8.5e-07 28.9 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain CoA_binding_3 PF13727.1 OAJ04842.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 CoA-binding domain Arrestin_N PF00339.24 OAJ04843.1 - 0.0024 17.6 0.1 0.008 16.0 0.0 1.9 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Glyco_hydro_cc PF11790.3 OAJ04844.1 - 9.9e-55 185.5 3.9 1.3e-54 185.1 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GP46 PF07409.7 OAJ04844.1 - 0.037 13.3 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Phage protein GP46 Abhydrolase_5 PF12695.2 OAJ04845.1 - 0.00028 20.6 0.0 0.00087 19.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ04845.1 - 0.00051 19.9 0.0 0.0024 17.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ04845.1 - 0.098 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 OAJ04845.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase CbiK PF06180.6 OAJ04845.1 - 0.23 10.5 0.0 2.6 7.0 0.0 2.0 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) Diphthamide_syn PF01866.12 OAJ04846.1 - 1.2e-74 251.2 0.0 9.5e-35 120.3 0.0 5.2 3 1 0 3 3 3 3 Putative diphthamide synthesis protein Bap31 PF05529.7 OAJ04848.1 - 0.55 9.6 2.5 0.97 8.8 1.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PUF PF00806.14 OAJ04849.1 - 1.1e-16 59.2 0.0 0.00094 18.5 0.0 6.8 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat Bot1p PF12298.3 OAJ04850.1 - 3.6e-24 85.6 0.0 3.6e-24 85.6 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 OAJ04850.1 - 0.016 15.1 0.0 0.016 15.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 TPR_11 PF13414.1 OAJ04851.1 - 1.3e-39 133.6 15.0 1.7e-16 59.6 1.2 5.3 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 OAJ04851.1 - 7.6e-29 97.2 16.0 6.1e-05 22.6 0.1 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ04851.1 - 8.1e-29 98.0 10.6 7.1e-05 22.2 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04851.1 - 1.2e-23 83.2 12.2 3.6e-06 27.5 0.1 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat DnaJ PF00226.26 OAJ04851.1 - 7e-23 80.1 1.0 2.5e-22 78.3 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.1 OAJ04851.1 - 4.6e-20 70.2 9.9 0.00095 19.5 0.0 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ04851.1 - 7.7e-20 71.0 13.4 3.8e-05 23.9 0.1 6.1 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04851.1 - 1.3e-17 63.5 15.1 2.2e-06 27.4 0.2 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 OAJ04851.1 - 6.9e-13 48.5 12.3 0.00021 21.3 0.1 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 OAJ04851.1 - 7e-12 44.1 2.8 0.082 12.7 0.1 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ04851.1 - 9.5e-11 41.3 6.6 0.0025 17.6 0.0 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ04851.1 - 2e-09 37.2 13.6 0.24 11.9 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ04851.1 - 3.2e-09 35.9 13.9 1.2 9.0 0.2 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ04851.1 - 0.00037 20.4 12.0 12 6.4 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ04851.1 - 0.0095 15.8 10.5 4.1 7.4 0.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat RPT PF13446.1 OAJ04851.1 - 0.01 15.2 0.0 0.046 13.1 0.0 2.1 1 0 0 1 1 1 0 A repeated domain in UCH-protein Fis1_TPR_C PF14853.1 OAJ04851.1 - 0.081 12.8 0.2 0.081 12.8 0.1 4.5 5 1 1 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 OAJ04851.1 - 0.31 11.5 10.5 0.33 11.4 0.4 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat MIT PF04212.13 OAJ04851.1 - 0.77 9.6 17.7 0.54 10.1 2.1 4.7 3 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain DUF1840 PF08895.6 OAJ04851.1 - 1.6 8.8 8.6 0.37 10.8 1.1 3.3 2 1 1 4 4 4 0 Domain of unknown function (DUF1840) F-box-like PF12937.2 OAJ04852.1 - 0.00015 21.4 0.4 0.00028 20.5 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ04852.1 - 0.0061 16.1 0.8 0.013 15.1 0.6 1.6 1 0 0 1 1 1 1 F-box domain Abhydrolase_5 PF12695.2 OAJ04853.1 - 0.0021 17.8 0.0 0.0053 16.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ04853.1 - 0.034 13.7 0.1 0.09 12.3 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein Transposase_21 PF02992.9 OAJ04856.1 - 1.9e-08 33.6 0.0 3.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ04856.1 - 9.2e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DZR PF12773.2 OAJ04856.1 - 0.033 13.9 1.1 0.46 10.3 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 OAJ04858.1 - 9.8e-48 158.4 29.1 7.7e-10 38.2 0.2 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 OAJ04858.1 - 3.2e-10 39.5 0.1 6.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 OAJ04858.1 - 1.4e-09 36.6 11.1 0.076 11.1 0.0 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 OAJ04858.1 - 0.00011 21.7 1.5 0.45 9.9 0.1 3.9 2 1 0 2 2 2 2 PQQ-like domain F-box PF00646.28 OAJ04858.1 - 0.00024 20.6 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 OAJ04858.1 - 0.0027 17.9 13.9 2.2 8.6 0.0 7.0 6 1 2 8 8 8 1 PQQ-like domain zf-RING_2 PF13639.1 OAJ04859.1 - 1.4e-06 27.9 0.8 4.9e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ04859.1 - 4.5e-05 23.0 0.5 0.00028 20.5 0.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ04859.1 - 0.00038 20.1 0.0 0.001 18.7 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger KIAA1430 PF13879.1 OAJ04859.1 - 0.0018 18.6 0.4 0.0018 18.6 0.3 2.5 2 1 1 3 3 3 1 KIAA1430 homologue zf-C3HC4_2 PF13923.1 OAJ04859.1 - 0.0023 17.9 0.1 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Lge1 PF11488.3 OAJ04859.1 - 0.01 16.0 0.3 0.01 16.0 0.2 3.6 3 2 1 4 4 4 0 Transcriptional regulatory protein LGE1 zf-C3HC4 PF00097.20 OAJ04859.1 - 0.012 15.2 2.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ04859.1 - 0.019 14.6 0.1 0.019 14.6 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GAGA_bind PF06217.7 OAJ04859.1 - 5.9 6.7 12.1 18 5.1 8.4 1.8 1 0 0 1 1 1 0 GAGA binding protein-like family CPSase_L_D2 PF02786.12 OAJ04860.1 - 2.1e-53 180.7 0.0 3.5e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.17 OAJ04860.1 - 4.9e-45 153.8 0.4 6.2e-44 150.1 0.3 2.0 1 1 0 1 1 1 1 Carboxyl transferase domain Biotin_carb_C PF02785.14 OAJ04860.1 - 8.8e-23 80.3 0.0 2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 OAJ04860.1 - 1.1e-19 70.4 0.0 2.7e-18 66.0 0.0 2.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 OAJ04860.1 - 1.3e-17 63.1 0.2 7.6e-17 60.7 0.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 OAJ04860.1 - 8e-10 38.2 0.8 0.00088 18.8 0.2 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.1 OAJ04860.1 - 2.1e-08 33.2 0.0 8.7e-08 31.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon DUF2118 PF09891.4 OAJ04860.1 - 0.0024 17.6 2.2 0.0053 16.4 0.0 2.6 3 1 1 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 OAJ04860.1 - 0.0031 16.7 2.2 0.17 11.0 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein MdcE PF06833.6 OAJ04860.1 - 0.0089 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) HlyD_3 PF13437.1 OAJ04860.1 - 0.065 13.5 0.2 0.65 10.3 0.2 2.5 1 1 1 2 2 2 0 HlyD family secretion protein NQRA PF05896.6 OAJ04860.1 - 0.082 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD PF00529.15 OAJ04860.1 - 0.11 11.7 6.7 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 OAJ04860.1 - 0.23 10.5 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Mitofilin PF09731.4 OAJ04862.1 - 0.0045 15.7 2.9 0.0054 15.4 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 OAJ04862.1 - 0.0094 15.4 1.1 0.012 15.1 0.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CHASE3 PF05227.8 OAJ04862.1 - 0.01 15.5 1.7 0.016 14.9 1.2 1.4 1 0 0 1 1 1 0 CHASE3 domain DUF603 PF04645.7 OAJ04862.1 - 0.029 14.3 0.8 0.037 13.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 UPF0278 PF08745.6 OAJ04862.1 - 0.033 13.4 0.2 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 UPF0278 family Baculo_PEP_C PF04513.7 OAJ04862.1 - 0.13 12.1 5.7 0.31 10.8 1.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 OAJ04862.1 - 0.38 11.1 5.2 4 7.8 2.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PIF1 PF05970.9 OAJ04865.1 - 2.6e-23 82.5 0.3 4.1e-22 78.6 0.0 2.3 2 1 1 3 3 3 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04865.1 - 2e-12 47.1 2.1 2e-11 43.8 0.0 2.6 1 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ04865.1 - 1.1e-09 38.3 0.6 2.6e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ04865.1 - 0.00031 20.4 0.2 0.00031 20.4 0.1 3.0 3 0 0 3 3 3 1 Part of AAA domain AT_hook PF02178.14 OAJ04866.1 - 0.44 10.3 7.5 1.1 9.1 5.2 1.7 1 0 0 1 1 1 0 AT hook motif P_C PF06640.6 OAJ04866.1 - 0.49 10.3 7.3 0.69 9.8 5.1 1.2 1 0 0 1 1 1 0 P protein C-terminus Herpes_UL25 PF01499.11 OAJ04867.1 - 0.014 13.7 0.1 0.018 13.4 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family Ribosomal_L28e PF01778.12 OAJ04867.1 - 0.18 12.1 2.1 0.33 11.3 1.5 1.3 1 0 0 1 1 1 0 Ribosomal L28e protein family ABC_tran PF00005.22 OAJ04870.1 - 9.6e-48 161.9 0.0 2e-30 105.8 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ04870.1 - 1.1e-33 116.8 32.8 1.1e-21 77.4 6.0 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ04870.1 - 1.5e-10 40.6 4.9 3.9e-05 22.9 0.5 4.7 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ04870.1 - 6.5e-08 31.9 0.3 0.0057 16.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ04870.1 - 8.2e-08 32.8 0.0 0.0023 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ04870.1 - 1.4e-07 31.6 1.7 4.7e-05 23.4 0.5 2.5 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 OAJ04870.1 - 1.8e-05 23.7 0.0 0.056 12.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 OAJ04870.1 - 1.8e-05 24.8 0.0 0.44 10.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ04870.1 - 5.4e-05 22.7 0.1 0.0021 17.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 OAJ04870.1 - 0.0001 21.7 0.4 0.011 15.1 0.0 3.0 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 OAJ04870.1 - 0.00014 21.6 0.8 0.0092 15.8 0.0 2.7 3 0 0 3 3 2 1 Dynamin family AAA_22 PF13401.1 OAJ04870.1 - 0.00017 21.7 0.2 0.057 13.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 OAJ04870.1 - 0.00032 20.6 0.0 0.98 9.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 OAJ04870.1 - 0.0013 19.2 0.0 2.9 8.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 OAJ04870.1 - 0.0031 16.7 0.4 0.48 9.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAJ04870.1 - 0.0034 17.2 0.1 1.6 8.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 OAJ04870.1 - 0.0065 15.9 0.2 1.9 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 OAJ04870.1 - 0.0094 15.6 0.6 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 OAJ04870.1 - 0.0099 14.5 0.0 0.55 8.7 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF87 PF01935.12 OAJ04870.1 - 0.012 15.4 0.3 0.03 14.1 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_30 PF13604.1 OAJ04870.1 - 0.012 15.1 0.6 0.54 9.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 OAJ04870.1 - 0.032 12.8 0.0 0.61 8.6 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.4 OAJ04870.1 - 0.047 12.3 0.3 0.15 10.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 OAJ04870.1 - 0.057 12.8 1.4 7 6.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 OAJ04870.1 - 0.058 14.2 0.0 4.7 8.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 OAJ04870.1 - 0.074 12.7 0.3 3.5 7.2 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 OAJ04870.1 - 0.087 12.7 0.1 7.1 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 OAJ04870.1 - 0.11 12.7 0.1 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 OAJ04870.1 - 0.19 11.4 1.0 2.4 7.8 0.7 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Septin PF00735.13 OAJ04870.1 - 0.27 10.2 0.0 2.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_15 PF13175.1 OAJ04870.1 - 0.83 8.6 0.0 14 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 OAJ04871.1 - 6.2e-46 156.0 0.0 1.4e-29 103.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ04871.1 - 9.8e-33 113.7 33.1 1.6e-21 76.9 8.1 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ04871.1 - 1.5e-11 43.9 1.1 0.00032 20.0 0.1 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ04871.1 - 9.2e-08 31.5 0.2 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ04871.1 - 2.2e-07 31.4 0.0 0.0024 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ04871.1 - 6.9e-07 29.4 1.0 0.00045 20.2 0.3 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 OAJ04871.1 - 3.9e-05 23.7 0.0 0.74 9.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 OAJ04871.1 - 0.00035 20.0 0.5 0.027 13.8 0.1 2.9 3 1 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ04871.1 - 0.00043 19.8 0.1 0.0072 15.8 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 OAJ04871.1 - 0.00047 20.0 0.3 0.02 14.7 0.0 2.9 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 OAJ04871.1 - 0.00056 19.8 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ04871.1 - 0.00058 20.0 0.2 0.09 12.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 OAJ04871.1 - 0.00059 18.8 0.3 0.48 9.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 OAJ04871.1 - 0.00069 19.5 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 OAJ04871.1 - 0.0013 18.5 0.5 0.0076 16.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 OAJ04871.1 - 0.0016 17.9 1.2 0.33 10.3 0.0 2.5 3 0 0 3 3 2 1 AAA-like domain SbcCD_C PF13558.1 OAJ04871.1 - 0.0073 16.2 0.0 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 OAJ04871.1 - 0.0077 15.9 0.7 3.9 7.1 0.0 2.8 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 OAJ04871.1 - 0.0089 16.5 0.0 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ABC_ATPase PF09818.4 OAJ04871.1 - 0.012 14.2 0.1 0.88 8.0 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 OAJ04871.1 - 0.012 14.8 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 OAJ04871.1 - 0.017 14.6 0.3 0.54 9.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 OAJ04871.1 - 0.042 12.4 0.2 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 OAJ04871.1 - 0.053 13.2 0.3 4.1 7.0 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 OAJ04871.1 - 0.065 13.1 0.1 7.7 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 OAJ04871.1 - 0.073 13.8 0.0 2.5 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 OAJ04871.1 - 0.25 9.9 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.14 OAJ04871.1 - 0.32 10.4 1.3 15 5.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 OAJ04871.1 - 0.35 9.8 0.0 5.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Septin NB-ARC PF00931.17 OAJ04871.1 - 0.76 8.5 2.1 8.6 5.1 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain TMEM154 PF15102.1 OAJ04871.1 - 1.9 8.1 0.0 1.9 8.1 0.0 2.8 3 0 0 3 3 2 0 TMEM154 protein family Abhydrolase_6 PF12697.2 OAJ04873.1 - 8.2e-30 104.3 0.1 1.1e-29 103.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ04873.1 - 5.5e-14 52.1 0.0 7.3e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ04873.1 - 8.2e-09 35.3 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 OAJ04873.1 - 2.5e-08 33.7 0.1 3.3e-06 26.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ04873.1 - 0.0002 21.1 0.5 0.0011 18.7 0.1 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Thioesterase PF00975.15 OAJ04873.1 - 0.017 15.3 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 OAJ04873.1 - 0.022 14.3 0.0 0.053 13.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF676 PF05057.9 OAJ04873.1 - 0.035 13.3 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase PF07224.6 OAJ04873.1 - 0.063 12.0 0.1 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase LCAT PF02450.10 OAJ04873.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HIG_1_N PF04588.8 OAJ04874.1 - 4e-19 68.0 0.3 5.6e-19 67.6 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Lyase_catalyt PF09093.6 OAJ04874.1 - 0.12 11.2 0.3 0.17 10.7 0.2 1.2 1 0 0 1 1 1 0 Lyase, catalytic MULE PF10551.4 OAJ04875.1 - 2.7e-08 33.8 0.0 7.9e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 OAJ04875.1 - 1.1e-07 32.3 0.2 1.6e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 OAJ04875.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Transcription factor AFT DUF1161 PF06649.7 OAJ04875.1 - 0.085 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) Ribosomal_S13_N PF08069.7 OAJ04875.1 - 0.32 10.8 1.2 2 8.3 0.0 2.7 4 0 0 4 4 4 0 Ribosomal S13/S15 N-terminal domain Helicase_C PF00271.26 OAJ04877.1 - 2.1e-10 40.3 0.4 4e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3491 PF11996.3 OAJ04878.1 - 3.4 5.0 0.1 4.9 4.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) PCNA_N PF00705.13 OAJ04879.1 - 1.9e-50 169.5 2.6 5.1e-50 168.2 0.9 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 OAJ04879.1 - 1.6e-43 147.6 0.0 7e-23 80.9 0.1 2.5 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 OAJ04879.1 - 1.1e-07 30.8 0.2 4.2e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 OAJ04879.1 - 5.8e-05 22.3 0.0 0.00016 20.8 0.0 1.7 1 1 0 1 1 1 1 Rad9 LRS4 PF10422.4 OAJ04879.1 - 0.0047 16.3 3.3 0.011 15.0 0.6 2.0 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 Myc_N PF01056.13 OAJ04879.1 - 0.0048 16.1 3.1 0.0066 15.6 2.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Sporozoite_P67 PF05642.6 OAJ04879.1 - 0.025 12.4 3.0 0.035 12.0 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BSP_II PF05432.6 OAJ04879.1 - 0.045 13.0 5.8 0.069 12.4 4.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 OAJ04879.1 - 0.15 12.3 3.5 0.28 11.4 2.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.20 OAJ04885.1 - 2.5e-47 161.2 0.0 3.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04885.1 - 2.6e-24 85.6 0.0 4.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04885.1 - 2.1e-08 33.5 0.0 5.8e-08 32.0 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Dimer_Tnp_hAT PF05699.9 OAJ04886.1 - 2.7e-15 55.7 0.4 7.2e-15 54.3 0.3 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ04886.1 - 0.18 11.7 0.1 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Pol_alpha_B_N PF08418.5 OAJ04887.1 - 0.81 9.1 3.2 1.2 8.6 2.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AdoMetDC_leader PF08132.6 OAJ04888.1 - 0.14 12.0 4.2 0.23 11.3 2.9 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide AT_hook PF02178.14 OAJ04888.1 - 5.4 7.0 10.1 11 6.0 7.0 1.6 1 0 0 1 1 1 0 AT hook motif Cyclin_N PF00134.18 OAJ04889.1 - 4e-13 49.0 0.0 5.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ04889.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain ATP-synt_B PF00430.13 OAJ04891.1 - 0.0058 16.4 1.7 0.0058 16.4 1.2 1.6 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) Baculo_PEP_C PF04513.7 OAJ04891.1 - 0.015 15.1 0.7 0.064 13.0 0.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4094 PF13334.1 OAJ04891.1 - 0.019 15.3 0.6 0.04 14.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DegS PF05384.6 OAJ04891.1 - 0.024 13.8 0.2 0.034 13.3 0.2 1.2 1 0 0 1 1 1 0 Sensor protein DegS DUF1640 PF07798.6 OAJ04891.1 - 0.049 13.6 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Hemerythrin PF01814.18 OAJ04891.1 - 0.057 13.5 0.4 0.25 11.5 0.3 1.9 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Ribosomal_S18 PF01084.15 OAJ04891.1 - 0.074 12.9 0.0 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S18 Prominin PF05478.6 OAJ04891.1 - 0.15 9.5 0.1 0.17 9.3 0.1 1.1 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 OAJ04891.1 - 0.17 11.3 4.3 0.47 9.9 3.0 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 OAJ04891.1 - 2.4 8.5 7.0 1.5 9.2 1.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PIF1 PF05970.9 OAJ04892.1 - 7.9e-23 80.9 0.0 1.6e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ04892.1 - 2.7e-14 53.1 0.3 4.9e-13 49.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain Helitron_like_N PF14214.1 OAJ04892.1 - 1.3e-10 41.3 0.1 4e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ04892.1 - 1.6e-06 27.7 1.7 3.5e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ04892.1 - 0.001 19.1 0.0 0.0038 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ04892.1 - 0.068 12.8 0.3 0.28 10.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAJ04892.1 - 0.086 12.3 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 OAJ04892.1 - 0.088 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-sulfurylase PF01747.12 OAJ04893.1 - 4.9e-87 290.7 0.1 6.9e-87 290.2 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 OAJ04893.1 - 3.7e-54 182.6 0.0 5.7e-54 182.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 OAJ04893.1 - 3.5e-50 169.5 0.0 5.7e-50 168.8 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain WD40 PF00400.27 OAJ04894.1 - 1.2e-14 53.4 0.7 5.4e-05 22.9 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat RabGAP-TBC PF00566.13 OAJ04895.1 - 6.8e-29 100.8 0.4 6.8e-29 100.8 0.3 3.5 4 0 0 4 4 4 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 OAJ04895.1 - 1.7e-05 24.2 0.0 0.00022 20.5 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) LytR_C PF13399.1 OAJ04895.1 - 0.04 14.3 1.2 0.13 12.6 0.8 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator DUF1005 PF06219.7 OAJ04896.1 - 0.044 12.4 2.6 0.079 11.6 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) DUF3015 PF11220.3 OAJ04896.1 - 0.064 12.8 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) RR_TM4-6 PF06459.7 OAJ04897.1 - 0.092 12.6 9.6 0.14 12.0 6.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 OmpH PF03938.9 OAJ04897.1 - 0.14 12.0 11.1 0.2 11.6 7.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ycf1 PF05758.7 OAJ04897.1 - 0.2 9.3 8.0 0.25 8.9 5.6 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 OAJ04897.1 - 0.45 10.2 5.2 0.6 9.8 3.6 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 OAJ04897.1 - 1.7 7.5 3.0 2.2 7.1 2.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MIP-T3 PF10243.4 OAJ04897.1 - 2.3 6.5 21.9 3.4 6.0 15.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 OAJ04897.1 - 2.4 5.7 4.6 3.2 5.2 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 OAJ04897.1 - 4 6.7 18.2 5.8 6.2 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ATP-synt_E PF05680.7 OAJ04897.1 - 9.2 6.2 9.9 17 5.4 6.9 1.4 1 0 0 1 1 1 0 ATP synthase E chain Solute_trans_a PF03619.11 OAJ04898.1 - 1.9e-86 289.8 9.3 2.5e-86 289.3 6.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MAPEG PF01124.13 OAJ04899.1 - 1.5e-13 50.4 5.7 1.9e-13 50.1 3.9 1.1 1 0 0 1 1 1 1 MAPEG family Rad9 PF04139.8 OAJ04900.1 - 1e-34 119.8 0.0 3.4e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.6 OAJ04900.1 - 7.1e-17 60.9 0.0 1.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 OAJ04900.1 - 0.0014 18.2 0.1 0.01 15.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin ICL PF00463.16 OAJ04901.1 - 2.9e-191 636.2 0.0 3.3e-191 636.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAJ04901.1 - 1.7e-10 40.5 0.0 3.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAJ04901.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Arginine repressor, C-terminal domain HAD PF12710.2 OAJ04902.1 - 8.6e-13 48.8 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 OAJ04902.1 - 1.1e-06 28.1 0.0 1.5e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 OAJ04902.1 - 6.5e-05 23.2 0.1 0.00036 20.8 0.1 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 OAJ04902.1 - 6.9e-05 22.1 0.3 0.00056 19.1 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 OAJ04902.1 - 0.00037 20.9 0.7 0.0017 18.8 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 OAJ04903.1 - 2.8e-53 181.1 0.0 3.1e-52 177.6 0.0 2.4 1 1 0 1 1 1 1 Cytochrome P450 Phyto-Amp PF15438.1 OAJ04904.1 - 0.085 12.4 0.5 7.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Antigenic membrane protein of phytoplasma ABC_tran PF00005.22 OAJ04905.1 - 1.6e-44 151.5 0.6 1.8e-22 80.1 0.0 4.8 4 2 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 OAJ04905.1 - 2.5e-19 70.3 1.9 0.00016 21.7 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 OAJ04905.1 - 2.6e-15 56.2 2.3 0.0063 15.7 0.0 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 OAJ04905.1 - 5.8e-10 38.5 0.3 0.00076 18.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 OAJ04905.1 - 1.6e-07 31.1 0.2 0.01 15.2 0.0 3.8 4 1 0 4 4 3 2 AAA-like domain CLASP_N PF12348.3 OAJ04905.1 - 3.3e-07 29.9 0.1 0.0042 16.4 0.0 2.5 1 1 1 2 2 2 2 CLASP N terminal HEAT_2 PF13646.1 OAJ04905.1 - 8e-07 29.2 0.6 0.00025 21.2 0.0 4.1 3 1 2 5 5 5 2 HEAT repeats AAA_17 PF13207.1 OAJ04905.1 - 2.3e-06 28.4 0.4 0.087 13.6 0.0 3.2 3 1 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 OAJ04905.1 - 2.6e-06 27.2 0.0 0.0044 16.9 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 OAJ04905.1 - 7e-06 25.3 0.0 0.11 11.5 0.0 4.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 OAJ04905.1 - 1e-05 25.6 0.0 0.21 11.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 OAJ04905.1 - 2.3e-05 23.6 0.0 0.025 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 HEAT PF02985.17 OAJ04905.1 - 2.4e-05 24.0 0.0 2.5 8.4 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat Miro PF08477.8 OAJ04905.1 - 2.9e-05 24.5 0.0 0.035 14.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ04905.1 - 3.9e-05 23.5 0.1 0.43 10.5 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 OAJ04905.1 - 4.3e-05 23.2 0.0 0.27 10.8 0.0 2.9 3 0 0 3 3 3 2 NACHT domain DUF87 PF01935.12 OAJ04905.1 - 6.3e-05 22.9 0.6 0.031 14.0 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_16 PF13191.1 OAJ04905.1 - 7.3e-05 22.8 0.2 0.33 10.9 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 OAJ04905.1 - 7.7e-05 23.1 8.7 0.055 13.7 0.0 3.5 4 1 0 4 4 2 2 AAA domain HEAT_EZ PF13513.1 OAJ04905.1 - 0.00011 22.5 1.2 15 6.2 0.0 5.8 4 2 0 5 5 5 0 HEAT-like repeat AAA_18 PF13238.1 OAJ04905.1 - 0.00015 22.1 0.1 0.41 10.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 OAJ04905.1 - 0.00018 21.4 0.0 0.91 9.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_13 PF13166.1 OAJ04905.1 - 0.00032 19.3 0.0 1.1 7.6 0.0 3.3 3 1 0 3 3 3 2 AAA domain MobB PF03205.9 OAJ04905.1 - 0.00038 20.1 1.3 0.57 9.8 0.0 3.7 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 OAJ04905.1 - 0.00054 20.1 0.0 0.82 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase FtsK_SpoIIIE PF01580.13 OAJ04905.1 - 0.00095 18.6 0.0 0.85 9.0 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family ArgK PF03308.11 OAJ04905.1 - 0.0015 17.3 1.1 0.45 9.2 0.0 3.1 3 0 0 3 3 3 1 ArgK protein G-alpha PF00503.15 OAJ04905.1 - 0.0018 17.0 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit Chromo PF00385.19 OAJ04905.1 - 0.0018 17.8 0.8 0.0037 16.9 0.0 1.9 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_25 PF13481.1 OAJ04905.1 - 0.002 17.5 0.0 0.66 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAJ04905.1 - 0.0022 18.0 0.0 0.85 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ04905.1 - 0.0037 17.4 0.0 6.2 7.0 0.0 4.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAJ04905.1 - 0.004 16.7 0.2 5.8 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 OAJ04905.1 - 0.0047 16.6 0.1 1.6 8.3 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 OAJ04905.1 - 0.014 14.2 2.4 2 7.2 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain DUF3584 PF12128.3 OAJ04905.1 - 0.016 12.5 4.0 0.44 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.7 OAJ04905.1 - 0.024 13.7 1.1 17 4.4 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 OAJ04905.1 - 0.032 14.1 0.0 4.1 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 OAJ04905.1 - 0.042 13.5 2.1 8.6 6.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 OAJ04905.1 - 0.048 13.1 0.3 3.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HVSL PF09749.4 OAJ04906.1 - 1.6e-32 112.4 0.0 2.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 OAJ04906.1 - 5.7e-06 26.1 0.9 8.8e-06 25.5 0.6 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily CTF_NFI PF00859.13 OAJ04906.1 - 0.0028 17.4 1.1 0.0028 17.4 0.8 1.8 2 0 0 2 2 2 1 CTF/NF-I family transcription modulation region tRNA-synt_1 PF00133.17 OAJ04907.1 - 1.6e-25 89.2 0.0 2.6e-17 62.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 OAJ04907.1 - 0.00013 20.8 0.1 0.00028 19.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 OAJ04907.1 - 0.016 14.5 0.0 0.049 12.9 0.0 1.8 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 PIG-P PF08510.7 OAJ04908.1 - 1.5e-23 82.7 1.2 2e-23 82.3 0.8 1.2 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 OAJ04908.1 - 0.46 10.8 2.3 0.8 10.0 1.6 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MutS_V PF00488.16 OAJ04909.1 - 9.3e-52 175.7 0.0 1.7e-51 174.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 OAJ04909.1 - 1.2e-05 25.2 0.0 4.8e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 OAJ04909.1 - 3.9e-05 23.7 4.9 0.092 12.8 0.4 4.4 3 1 0 3 3 3 1 MutS domain II SMC_N PF02463.14 OAJ04909.1 - 0.0064 15.7 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DAP3 PF10236.4 OAJ04909.1 - 0.035 13.0 2.0 0.13 11.2 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.1 OAJ04909.1 - 0.056 13.5 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF1348 PF07080.6 OAJ04910.1 - 7.9e-48 161.9 5.7 9.4e-48 161.6 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 OAJ04910.1 - 7.5e-06 26.2 0.1 1e-05 25.8 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 OAJ04910.1 - 0.038 14.1 0.0 0.072 13.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) SHR3_chaperone PF08229.6 OAJ04911.1 - 8.8e-31 106.3 1.7 3.3e-30 104.5 1.2 1.7 1 1 0 1 1 1 1 ER membrane protein SH3 Ras PF00071.17 OAJ04912.1 - 2.3e-48 163.6 0.0 2.9e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ04912.1 - 7.4e-16 58.7 0.0 1e-15 58.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ04912.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ04912.1 - 0.01 15.2 0.0 0.085 12.2 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 OAJ04912.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1771 PF08590.5 OAJ04913.1 - 2.8e-17 62.4 6.7 5.8e-17 61.4 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ04913.1 - 1.1e-12 47.9 0.2 2.5e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Smr domain Asp PF00026.18 OAJ04914.1 - 5.2e-45 154.0 0.0 1.1e-44 153.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ04914.1 - 5.4e-05 23.2 0.1 0.00058 19.8 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 OAJ04914.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease NYN PF01936.13 OAJ04915.1 - 2e-22 80.0 0.0 5e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 NYN domain adh_short_C2 PF13561.1 OAJ04916.1 - 5.5e-29 101.6 0.0 6.7e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ04916.1 - 3.6e-16 59.5 0.1 4.6e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ04916.1 - 1.3e-06 28.2 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 OAJ04916.1 - 0.0018 17.3 0.1 0.0043 16.1 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 OAJ04916.1 - 0.0024 17.9 0.2 0.0054 16.7 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 OAJ04916.1 - 0.0032 17.5 0.1 0.0092 16.0 0.1 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ04916.1 - 0.0038 17.4 0.1 0.0083 16.3 0.0 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 OAJ04916.1 - 0.0064 16.1 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 OAJ04916.1 - 0.045 12.3 0.0 0.13 10.8 0.0 1.6 1 1 1 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Eno-Rase_NADH_b PF12242.3 OAJ04916.1 - 0.14 11.9 0.6 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PPTA PF01239.17 OAJ04918.1 - 1.1e-39 132.1 7.4 2.2e-09 36.2 0.0 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 OAJ04918.1 - 0.0063 16.6 0.4 10 6.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ04918.1 - 0.12 13.0 3.0 3.5 8.5 0.1 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ04918.1 - 0.2 11.3 2.5 4.1 7.1 0.0 3.4 4 0 0 4 4 4 0 TPR repeat p450 PF00067.17 OAJ04919.1 - 3.5e-51 174.1 0.0 1.1e-49 169.2 0.0 2.9 1 1 0 1 1 1 1 Cytochrome P450 RPEL PF02755.10 OAJ04920.1 - 7.8e-19 66.3 9.7 1.5e-07 30.4 1.5 3.4 3 0 0 3 3 3 3 RPEL repeat DUF1992 PF09350.5 OAJ04920.1 - 0.32 10.8 4.7 2.1 8.2 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1992) DUF1227 PF06777.6 OAJ04923.1 - 8.5e-57 190.9 0.0 1.6e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 OAJ04923.1 - 1.2e-45 154.9 0.0 1.5e-40 138.4 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 OAJ04923.1 - 1.3e-45 155.4 0.0 2.6e-45 154.3 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 OAJ04923.1 - 0.0033 16.2 0.1 0.041 12.6 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ04923.1 - 0.0083 15.9 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ04923.1 - 0.02 14.4 0.0 4 6.8 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ04923.1 - 0.043 13.9 0.2 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 OAJ04923.1 - 0.064 13.0 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain YtxC PF08812.6 OAJ04923.1 - 0.093 12.2 0.6 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 YtxC-like family AAA_11 PF13086.1 OAJ04923.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 OAJ04923.1 - 0.16 11.1 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DNA_pol_E_B PF04042.11 OAJ04924.1 - 7.4e-46 156.0 0.2 1e-45 155.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 OAJ04924.1 - 0.0022 17.8 0.0 0.027 14.2 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NTP_transf_2 PF01909.18 OAJ04926.1 - 0.079 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Pkinase PF00069.20 OAJ04927.1 - 8.9e-66 221.6 0.0 8.9e-66 221.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04927.1 - 1.5e-42 145.5 0.0 2.8e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ04927.1 - 1.2e-06 27.7 0.1 2.3e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 OAJ04927.1 - 1.5 7.6 0.0 2.3 6.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SelP_N PF04592.9 OAJ04927.1 - 5.5 6.2 27.4 8.1 5.7 7.7 3.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region XPG_N PF00752.12 OAJ04928.1 - 9.5e-32 109.2 0.0 1.8e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain CNH PF00780.17 OAJ04928.1 - 4.7e-08 32.7 0.0 1.6e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 OAJ04928.1 - 1.3e-05 25.3 0.3 1.3e-05 25.3 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 OAJ04928.1 - 0.21 11.6 0.3 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Exo_endo_phos PF03372.18 OAJ04931.1 - 3.7e-17 63.0 0.5 1.6e-16 60.9 0.4 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PFK PF00365.15 OAJ04932.1 - 4.7e-165 547.4 3.4 7.5e-97 323.6 0.2 3.2 3 0 0 3 3 3 3 Phosphofructokinase FAM216B PF15107.1 OAJ04932.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 FAM216B protein family EXOSC1 PF10447.4 OAJ04933.1 - 3.6e-27 94.1 0.1 6e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Peptidase_C97 PF05903.9 OAJ04934.1 - 5.3e-15 55.5 0.0 5.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain RRM_1 PF00076.17 OAJ04935.1 - 3.8e-13 48.8 0.0 5.9e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ04935.1 - 2.2e-08 33.9 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 OAJ04935.1 - 4.3e-06 27.0 0.2 4.3e-06 27.0 0.1 2.9 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 OAJ04935.1 - 0.055 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gar1 PF04410.9 OAJ04936.1 - 2.6e-24 85.4 9.5 3.5e-14 52.5 0.0 3.8 3 1 0 3 3 3 2 Gar1/Naf1 RNA binding region HAP1_N PF04849.8 OAJ04937.1 - 0.28 10.1 18.2 0.21 10.5 6.4 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF648 PF04890.8 OAJ04937.1 - 0.61 9.1 0.1 1 8.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) CENP-F_leu_zip PF10473.4 OAJ04937.1 - 1.7 8.4 22.0 1.2 8.9 4.1 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 OAJ04937.1 - 8.8 5.4 18.0 0.57 9.3 2.6 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TFIIS_M PF07500.9 OAJ04938.1 - 6.9e-20 71.2 0.1 1.1e-19 70.5 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 OAJ04938.1 - 1.9e-10 40.2 6.6 3e-10 39.6 4.6 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 OAJ04938.1 - 2.1e-08 34.6 0.0 4.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain Hid1 PF12722.2 OAJ04938.1 - 0.17 9.5 0.5 0.24 9.0 0.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_2 PF13639.1 OAJ04938.1 - 3.2 7.6 5.1 5.7 6.8 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain DUF2890 PF11081.3 OAJ04938.1 - 5.5 6.9 9.9 0.22 11.5 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Sfi1 PF08457.5 OAJ04940.1 - 4.6e-24 84.7 80.5 4.7e-15 55.0 40.0 5.0 1 1 2 3 3 3 3 Sfi1 spindle body protein PCNP PF15473.1 OAJ04940.1 - 0.002 18.4 0.2 0.0076 16.5 0.1 1.9 1 1 0 1 1 1 1 PEST, proteolytic signal-containing nuclear protein family Ribosomal_60s PF00428.14 OAJ04940.1 - 0.1 13.0 9.4 0.055 13.8 0.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein SMC_N PF02463.14 OAJ04941.1 - 5.6e-69 231.7 1.4 7.9e-69 231.2 1.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ04941.1 - 1.8e-31 108.5 0.1 6.9e-31 106.7 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ04941.1 - 2.3e-14 54.0 8.3 1.8e-06 28.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 OAJ04941.1 - 1.5e-10 41.7 43.2 1.5e-10 41.7 29.9 7.0 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 OAJ04941.1 - 0.0024 17.3 0.0 0.0075 15.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 OAJ04941.1 - 0.26 10.7 0.0 0.26 10.7 0.0 4.7 4 0 0 4 4 4 0 FtsK/SpoIIIE family HlyIII PF03006.15 OAJ04944.1 - 2.6e-57 193.7 14.3 4.3e-57 193.0 9.9 1.4 1 1 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.10 OAJ04944.1 - 0.043 13.8 1.1 0.13 12.3 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family GWT1 PF06423.7 OAJ04944.1 - 1.6 8.8 4.8 30 4.7 0.1 2.5 1 1 1 2 2 2 0 GWT1 DDE_Tnp_4 PF13359.1 OAJ04945.1 - 4.2e-20 71.9 0.0 7.5e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease FH2 PF02181.18 OAJ04947.1 - 6.4e-64 216.1 3.6 6.4e-64 216.1 2.5 2.5 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 OAJ04947.1 - 4.2e-45 153.4 0.0 4.2e-45 153.4 0.0 2.4 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 OAJ04947.1 - 5.5e-43 146.6 0.6 3.5e-42 144.0 0.0 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain Zip PF02535.17 OAJ04948.1 - 7.2e-31 107.3 23.6 1.1e-21 77.2 1.8 4.1 3 1 1 4 4 4 3 ZIP Zinc transporter ATE_C PF04377.10 OAJ04948.1 - 0.02 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Mg-por_mtran_C PF07109.6 OAJ04948.1 - 0.04 13.9 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium-protoporphyrin IX methyltransferase C-terminus PspC PF04024.7 OAJ04948.1 - 0.063 12.7 0.4 4.8 6.7 0.1 2.8 2 0 0 2 2 2 0 PspC domain FGF PF00167.13 OAJ04948.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Fibroblast growth factor DUF605 PF04652.11 OAJ04948.1 - 0.27 10.5 21.7 0.16 11.3 0.1 2.2 2 0 0 2 2 2 0 Vta1 like SMI1_KNR4 PF09346.5 OAJ04949.1 - 1.2e-24 86.7 0.0 1.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) TPR_11 PF13414.1 OAJ04950.1 - 1e-19 69.9 0.8 1.7e-12 46.8 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ04950.1 - 3.3e-11 42.2 2.6 0.011 15.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ04950.1 - 3.9e-11 42.0 0.7 0.0043 16.5 0.0 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ04950.1 - 1.7e-08 34.8 3.1 1.3e-05 25.7 1.0 3.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ04950.1 - 0.0022 17.8 0.6 1.4 8.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ04950.1 - 0.0035 17.1 0.7 0.015 15.1 0.5 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-RING_4 PF14570.1 OAJ04950.1 - 0.059 12.9 0.4 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_17 PF13431.1 OAJ04950.1 - 0.078 13.2 0.2 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 OAJ04952.1 - 1.1e-70 237.7 0.0 1.4e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ04952.1 - 1.3e-38 132.5 0.0 1.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 OAJ04952.1 - 2.1e-06 27.2 0.1 4.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 OAJ04952.1 - 3.5e-05 22.9 0.1 0.00019 20.5 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ04952.1 - 0.00085 18.3 0.0 0.0088 15.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ04952.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 OAJ04952.1 - 0.011 15.4 0.4 0.054 13.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ04952.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 OAJ04953.1 - 3e-05 23.7 3.2 16 5.6 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat SSB PF00436.20 OAJ04954.1 - 6e-15 54.9 0.0 7.4e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family G-gamma PF00631.17 OAJ04954.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 GGL domain Dimer_Tnp_hAT PF05699.9 OAJ04955.1 - 6.2e-20 70.6 0.0 1.2e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ADH_N PF08240.7 OAJ04956.1 - 0.031 14.0 1.2 0.047 13.4 0.9 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 OAJ04956.1 - 0.2 11.6 8.7 0.32 10.9 6.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4140 PF13600.1 OAJ04956.1 - 0.2 12.0 2.2 1.9 8.9 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RVT_2 PF07727.9 OAJ04958.1 - 6.4e-12 44.9 0.0 7.7e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXT2_N PF08595.6 OAJ04959.1 - 0.062 13.1 1.3 0.089 12.5 0.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Tom22 PF04281.8 OAJ04959.1 - 3 7.3 7.3 5.7 6.4 5.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.1 OAJ04959.1 - 6.3 7.1 14.9 12 6.2 10.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TruD PF01142.13 OAJ04962.1 - 2.4e-44 151.5 0.0 1.7e-27 96.1 0.0 5.8 6 1 0 6 6 6 5 tRNA pseudouridine synthase D (TruD) DUF2155 PF09923.4 OAJ04963.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) EF-hand_4 PF12763.2 OAJ04963.1 - 0.13 12.0 0.1 0.24 11.1 0.0 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Proteasome PF00227.21 OAJ04968.1 - 9.2e-30 103.3 0.0 1.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DnaJ PF00226.26 OAJ04969.1 - 3.6e-16 58.6 0.3 6.8e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Med3 PF11593.3 OAJ04969.1 - 0.16 11.1 5.0 0.22 10.6 3.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Saccharop_dh PF03435.13 OAJ04970.1 - 7.8e-106 354.2 0.0 1.2e-105 353.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 OAJ04970.1 - 3.5e-87 291.4 0.0 6.3e-87 290.5 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Semialdhyde_dh PF01118.19 OAJ04970.1 - 4.2e-05 23.8 1.2 0.00022 21.4 0.1 2.8 4 0 0 4 4 4 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 OAJ04970.1 - 0.00066 19.7 0.1 0.0026 17.7 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_26 PF13659.1 OAJ04970.1 - 0.0015 18.5 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ04970.1 - 0.0099 16.3 0.1 0.42 11.1 0.0 3.1 2 2 0 2 2 2 1 Methyltransferase domain NmrA PF05368.8 OAJ04970.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.17 OAJ04970.1 - 0.15 12.5 0.5 0.44 11.0 0.1 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TFIID-18kDa PF02269.11 OAJ04971.1 - 6e-32 109.3 1.0 1.1e-30 105.2 0.5 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF4658 PF15555.1 OAJ04971.1 - 0.15 11.9 0.6 3.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) Histone PF00125.19 OAJ04972.1 - 5.2e-10 39.3 0.0 6.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ04972.1 - 0.0038 17.3 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 OAJ04972.1 - 0.013 15.3 0.0 0.02 14.8 0.0 1.4 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 OAJ04972.1 - 0.025 13.8 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4095 PF13338.1 OAJ04972.1 - 0.027 14.5 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) THEG PF14912.1 OAJ04975.1 - 0.11 13.0 3.6 0.28 11.7 2.5 1.7 1 0 0 1 1 1 0 Testicular haploid expressed repeat FAD_binding_8 PF08022.7 OAJ04976.1 - 1.3e-15 57.1 0.0 2.1e-10 40.3 0.0 2.5 1 1 1 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 OAJ04976.1 - 2.4e-13 50.2 15.0 2.4e-13 50.2 10.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ04976.1 - 2.2e-09 37.3 0.0 4.8e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Gti1_Pac2 PF09729.4 OAJ04977.1 - 5.7e-36 123.9 18.1 2.4e-30 105.6 0.0 4.8 3 1 1 4 4 4 2 Gti1/Pac2 family Ribosomal_L21p PF00829.16 OAJ04980.1 - 2e-08 34.2 1.8 7.3e-07 29.2 2.0 2.1 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein NDUF_B4 PF07225.7 OAJ04981.1 - 0.017 14.9 0.1 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Cytochrom_B559 PF00283.14 OAJ04981.1 - 0.043 13.1 0.7 0.062 12.5 0.5 1.2 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Clathrin PF00637.15 OAJ04982.1 - 5.7e-27 94.0 0.1 1.1e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 OAJ04982.1 - 0.0012 18.6 0.4 0.009 15.8 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 OAJ04982.1 - 0.029 14.4 0.1 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 OAJ04982.1 - 0.11 12.2 3.7 0.66 9.8 0.8 2.5 2 0 0 2 2 2 0 Ring finger domain OPT PF03169.10 OAJ04983.1 - 2.8e-134 448.8 2.6 3.5e-134 448.5 1.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein F-box-like PF12937.2 OAJ04984.1 - 0.00024 20.7 0.3 0.00065 19.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like DUF432 PF04254.8 OAJ04984.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Pol_alpha_B_N PF08418.5 OAJ04985.1 - 1.4 8.3 6.6 2.1 7.8 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Glyco_hydro_63 PF03200.11 OAJ04986.1 - 5.8e-231 768.6 0.0 4.9e-230 765.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 OAJ04986.1 - 2.4e-05 23.1 0.0 3.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 OAJ04986.1 - 0.041 12.0 0.0 0.14 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase MFS_1 PF07690.11 OAJ04987.1 - 1.1e-39 136.1 43.3 6.4e-39 133.6 29.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ04987.1 - 2.4e-15 55.7 12.5 3.9e-15 55.0 8.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ04987.1 - 1.5e-12 46.8 15.3 1.5e-12 46.8 10.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2619 PF10942.3 OAJ04987.1 - 0.12 12.2 2.8 0.22 11.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2619) MFS_1 PF07690.11 OAJ04988.1 - 2.4e-18 65.9 28.2 2.4e-18 65.9 19.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 OAJ04988.1 - 6.1e-15 55.0 6.4 6.1e-15 55.0 4.4 2.8 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 bZIP_2 PF07716.10 OAJ04989.1 - 1.5e-09 37.5 12.8 1.5e-09 37.5 8.9 3.6 2 1 0 2 2 2 1 Basic region leucine zipper Mem_trans PF03547.13 OAJ04989.1 - 0.0043 15.4 0.1 0.0053 15.0 0.1 1.2 1 0 0 1 1 1 1 Membrane transport protein Otopetrin PF03189.8 OAJ04989.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Otopetrin SAPS PF04499.10 OAJ04989.1 - 0.11 11.0 17.8 0.021 13.5 9.2 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein LMBR1 PF04791.11 OAJ04989.1 - 2.5 6.5 6.6 3.9 5.9 4.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_coat_CotO PF14153.1 OAJ04989.1 - 2.5 7.4 38.1 0.056 12.8 20.6 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Band_3_cyto PF07565.8 OAJ04989.1 - 8.2 5.8 29.3 18 4.7 20.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serglycin PF04360.7 OAJ04990.1 - 0.028 14.1 6.3 0.045 13.4 4.3 1.3 1 0 0 1 1 1 0 Serglycin DUF619 PF04768.8 OAJ04991.1 - 6e-29 100.6 0.0 1.8e-19 69.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF619) DUF572 PF04502.8 OAJ04991.1 - 0.0072 15.5 0.1 0.0072 15.5 0.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF572) Nop14 PF04147.7 OAJ04991.1 - 2.2 6.0 6.1 3.2 5.5 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family PIF1 PF05970.9 OAJ04992.1 - 3.8e-07 29.3 0.0 7.5e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 PIF1-like helicase UvrD_C_2 PF13538.1 OAJ04992.1 - 0.0014 18.7 0.1 0.022 14.8 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 OAJ04995.1 - 2.7e-07 30.3 0.2 5.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 OAJ04995.1 - 3e-07 29.7 0.1 3.8e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 OAJ04995.1 - 1.5e-06 27.8 0.2 4.9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ04995.1 - 0.014 15.3 0.4 0.19 11.7 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain PhoH PF02562.11 OAJ04995.1 - 0.18 11.0 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein Retrotrans_gag PF03732.12 OAJ04996.1 - 0.03 14.4 0.1 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein KfrA_N PF11740.3 OAJ04996.1 - 0.046 14.1 6.0 0.25 11.7 0.7 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term rve PF00665.21 OAJ04997.1 - 4e-16 59.2 0.0 9e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 OAJ04997.1 - 1.9e-15 56.7 0.0 3.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ04997.1 - 0.00047 20.6 0.0 0.0027 18.1 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DUF677 PF05055.7 OAJ04999.1 - 0.035 12.7 0.6 0.054 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Phlebovirus_G2 PF07245.6 OAJ04999.1 - 0.11 10.7 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Cep57_MT_bd PF06657.8 OAJ04999.1 - 0.19 11.7 1.2 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RVT_2 PF07727.9 OAJ05000.1 - 4.6e-79 264.8 0.0 8e-79 264.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 OAJ05000.1 - 3.6e-31 107.1 0.2 3.1e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ05000.1 - 4.5e-22 78.0 2.1 7.1e-10 38.7 0.1 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type rve PF00665.21 OAJ05000.1 - 5.1e-19 68.5 0.0 3.2e-18 65.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain UBN2_3 PF14244.1 OAJ05000.1 - 1.6e-13 50.4 0.0 2.9e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type RVP PF00077.15 OAJ05000.1 - 1.7e-07 31.0 0.1 0.039 13.8 0.0 3.1 3 0 0 3 3 3 2 Retroviral aspartyl protease DUF4219 PF13961.1 OAJ05000.1 - 8.3e-06 25.0 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4219) zf-CCHC_2 PF13696.1 OAJ05000.1 - 2.3e-05 23.7 7.6 0.049 13.1 0.6 2.8 2 0 0 2 2 2 2 Zinc knuckle Copper-fist PF00649.13 OAJ05000.1 - 3e-05 23.1 1.7 0.2 10.8 0.1 2.7 2 0 0 2 2 2 2 Copper fist DNA binding domain gag_pre-integrs PF13976.1 OAJ05000.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 OAJ05000.1 - 0.00075 19.3 17.0 0.13 12.2 3.2 2.7 2 0 0 2 2 2 2 Zinc knuckle TfoX_C PF04994.8 OAJ05000.1 - 0.024 14.5 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 TfoX C-terminal domain Ish1 PF10281.4 OAJ05000.1 - 0.046 13.7 0.2 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein rve_3 PF13683.1 OAJ05000.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RNA_pol PF00940.14 OAJ05000.1 - 0.18 10.2 0.0 14 3.9 0.0 2.2 2 0 0 2 2 2 0 DNA-dependent RNA polymerase Nucleoside_tran PF01733.13 OAJ05001.1 - 4.9e-22 78.4 5.9 3.9e-19 68.9 5.3 3.8 2 1 0 2 2 2 1 Nucleoside transporter CENP-B_dimeris PF09026.5 OAJ05001.1 - 7.3 6.8 7.4 0.97 9.7 1.1 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain PIF1 PF05970.9 OAJ05002.1 - 3.3e-53 180.9 0.0 4.8e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ05002.1 - 8.5e-35 120.1 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ05002.1 - 6.1e-05 22.6 0.0 0.00017 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ05002.1 - 0.01 15.5 0.1 0.01 15.5 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 OAJ05002.1 - 0.023 13.6 0.0 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 OAJ05002.1 - 0.22 11.6 0.0 0.53 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.3 OAJ05002.1 - 0.37 9.3 0.1 0.61 8.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CAP_N PF01213.14 OAJ05003.1 - 3.8 6.7 6.0 5.3 6.2 4.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DnaJ PF00226.26 OAJ05004.1 - 0.034 13.8 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Frataxin_Cyay PF01491.11 OAJ05006.1 - 2.2e-25 88.5 0.0 3e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain Ric8 PF10165.4 OAJ05007.1 - 1.5e-56 192.1 9.1 6.7e-55 186.6 6.0 2.9 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Esterase PF00756.15 OAJ05008.1 - 4.7e-39 134.3 0.0 6.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 OAJ05008.1 - 4.4e-06 26.5 0.0 6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 OAJ05008.1 - 0.051 12.4 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme MIS13 PF08202.6 OAJ05009.1 - 2.2e-16 59.8 0.0 1.9e-13 50.1 0.0 3.3 2 1 0 2 2 2 2 Mis12-Mtw1 protein family DivIC PF04977.10 OAJ05009.1 - 0.058 12.8 1.9 0.094 12.2 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 OAJ05009.1 - 0.23 11.0 0.6 0.92 9.0 0.1 2.0 2 0 0 2 2 2 0 IncA protein DUF1754 PF08555.5 OAJ05010.1 - 1.4e-14 54.4 6.2 1.4e-14 54.4 4.3 1.9 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MelC1 PF06236.6 OAJ05010.1 - 0.034 14.1 0.4 0.045 13.7 0.2 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Macoilin PF09726.4 OAJ05010.1 - 0.062 11.5 15.3 0.073 11.3 10.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_S4 PF00163.14 OAJ05010.1 - 0.11 12.9 1.2 0.2 12.0 0.9 1.6 1 1 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain Hex_IIIa PF02455.11 OAJ05010.1 - 0.21 10.2 6.1 0.25 10.0 4.2 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) NAM-associated PF14303.1 OAJ05010.1 - 0.97 9.7 10.8 1.2 9.4 7.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CTNNB1_binding PF08347.6 OAJ05010.1 - 1 9.5 10.0 1.6 8.9 6.9 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding GET2 PF08690.5 OAJ05010.1 - 1 8.5 8.3 1.2 8.2 5.7 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Herpes_DNAp_acc PF04929.7 OAJ05010.1 - 1.9 7.3 13.4 2.3 7.1 9.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CytochromB561_N PF09786.4 OAJ05010.1 - 2.5 6.4 10.9 2.8 6.3 7.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2217 PF10265.4 OAJ05010.1 - 4.4 5.9 7.9 5 5.7 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SOBP PF15279.1 OAJ05010.1 - 8.1 6.7 9.0 9 6.5 6.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DDHD PF02862.12 OAJ05010.1 - 8.6 6.0 10.3 11 5.7 7.1 1.2 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.5 OAJ05010.1 - 9 4.5 8.9 11 4.2 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 OAJ05010.1 - 9.8 5.9 9.6 12 5.7 6.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 THOC7 PF05615.8 OAJ05017.1 - 1.1e-13 51.6 3.9 1.1e-13 51.6 2.7 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 AAA_13 PF13166.1 OAJ05017.1 - 0.00071 18.1 1.7 0.00071 18.1 1.2 1.6 2 0 0 2 2 2 1 AAA domain Mnd1 PF03962.10 OAJ05017.1 - 0.0031 17.2 2.0 0.0031 17.2 1.4 2.6 2 1 1 3 3 3 1 Mnd1 family DivIC PF04977.10 OAJ05017.1 - 0.054 12.9 15.0 1.4 8.4 1.0 3.8 3 0 0 3 3 3 0 Septum formation initiator TBPIP PF07106.8 OAJ05017.1 - 0.12 11.8 1.5 0.29 10.6 1.1 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE PF05008.10 OAJ05017.1 - 1.5 8.9 7.0 2.7 8.2 0.0 3.7 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TMF_DNA_bd PF12329.3 OAJ05017.1 - 7.6 6.4 10.9 3.4 7.5 0.1 3.9 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding WBP-1 PF11669.3 OAJ05018.1 - 8.7 6.4 6.2 24 5.0 0.0 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 Cauli_VI PF01693.11 OAJ05019.1 - 6e-16 58.1 0.2 9.3e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3432 PF11914.3 OAJ05019.1 - 0.039 13.9 0.2 0.045 13.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Cauli_VI PF01693.11 OAJ05021.1 - 1.3e-14 53.8 0.3 2e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pentapeptide_2 PF01469.13 OAJ05022.1 - 0.058 13.0 0.6 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) RNase_H PF00075.19 OAJ05024.1 - 4.4e-26 91.7 0.0 5.8e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 OAJ05024.1 - 6.6e-17 61.2 0.1 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin PROL5-SMR PF15621.1 OAJ05025.1 - 0.69 10.3 10.7 1 9.8 7.4 1.2 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family RRF PF01765.14 OAJ05026.1 - 2.1e-33 115.1 0.1 3.7e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Ribosom_S12_S23 PF00164.20 OAJ05027.1 - 1.3e-44 150.4 0.2 1.7e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 MGC-24 PF05283.6 OAJ05028.1 - 0.0027 17.5 3.0 0.0032 17.3 1.0 1.9 1 1 1 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) DUF3357 PF11837.3 OAJ05028.1 - 0.086 12.6 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Rax2 PF12768.2 OAJ05028.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Histone PF00125.19 OAJ05030.1 - 1.3e-24 86.0 0.6 2.3e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 OAJ05030.1 - 8e-06 25.3 0.6 1.1e-05 24.9 0.4 1.4 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 OAJ05030.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 OAJ05030.1 - 0.0048 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ05030.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Transposase_21 PF02992.9 OAJ05032.1 - 4.4e-23 81.5 0.0 8.4e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ05032.1 - 0.0044 16.4 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Ribosomal_S8 PF00410.14 OAJ05033.1 - 1.3e-23 83.1 0.0 1.8e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 OAJ05034.1 - 8.4e-58 193.4 0.0 1e-57 193.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 zf-BED PF02892.10 OAJ05035.1 - 0.15 11.8 1.1 0.36 10.6 0.8 1.6 1 0 0 1 1 1 0 BED zinc finger DDE_Tnp_4 PF13359.1 OAJ05037.1 - 5.7e-20 71.5 0.0 1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ05037.1 - 0.087 12.3 3.8 5.1 6.5 0.2 3.1 2 1 1 3 3 3 0 Transposase DDE domain DUF883 PF05957.8 OAJ05038.1 - 0.0031 17.8 4.7 0.033 14.5 0.1 2.7 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF883) PP_kinase_N PF13089.1 OAJ05038.1 - 0.12 12.4 0.2 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain Sfi1_C PF10638.4 OAJ05038.1 - 0.13 12.7 0.3 9.7 6.6 0.2 2.2 2 0 0 2 2 2 0 Spindle body associated protein C-terminus DUF3673 PF12425.3 OAJ05038.1 - 0.25 11.2 4.4 7.4 6.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3673) DUF2457 PF10446.4 OAJ05039.1 - 0.12 11.0 1.2 0.11 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RskA PF10099.4 OAJ05039.1 - 0.15 11.8 6.1 0.17 11.6 4.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA NOA36 PF06524.7 OAJ05039.1 - 0.22 10.7 2.7 0.24 10.6 1.9 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_primase_lrg PF04104.9 OAJ05040.1 - 2.2e-77 259.8 0.0 3.1e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KH_1 PF00013.24 OAJ05041.1 - 2.7e-05 23.7 0.3 8e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 KH domain RAP1 PF07218.6 OAJ05041.1 - 0.0052 14.9 1.7 0.007 14.5 1.2 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) DEAD PF00270.24 OAJ05042.1 - 6.6e-40 136.3 0.0 1.9e-39 134.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ05042.1 - 5.8e-27 93.3 0.0 8e-26 89.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mitofilin PF09731.4 OAJ05042.1 - 0.002 16.8 14.5 0.0025 16.5 10.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SAPS PF04499.10 OAJ05042.1 - 1.7 7.2 12.6 2.3 6.7 8.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 OAJ05042.1 - 1.7 7.0 34.0 2.3 6.5 23.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HGTP_anticodon2 PF12745.2 OAJ05042.1 - 4.1 6.4 18.0 6.7 5.7 12.5 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4207 PF13904.1 OAJ05043.1 - 0.0016 17.8 0.3 0.0016 17.8 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) NRDE-2 PF08424.5 OAJ05043.1 - 0.26 10.1 2.5 0.39 9.5 1.7 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Nucleoplasmin PF03066.10 OAJ05043.1 - 2.7 7.4 9.6 2.6 7.5 0.6 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 OAJ05043.1 - 4.5 7.5 11.2 0.96 9.6 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 OAJ05043.1 - 6.3 6.5 6.4 10 5.8 0.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Glyco_hydro_8 PF01270.12 OAJ05044.1 - 2.4e-35 121.8 0.0 2.8e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.10 OAJ05044.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Sec10 PF07393.6 OAJ05045.1 - 7.6e-78 262.4 0.0 1.1e-77 261.8 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 Birna_VP4 PF01768.11 OAJ05045.1 - 0.27 10.2 2.3 0.41 9.6 1.6 1.2 1 0 0 1 1 1 0 Birnavirus VP4 protein F-box-like PF12937.2 OAJ05046.1 - 0.056 13.1 2.2 0.065 12.9 0.1 2.2 2 0 0 2 2 2 0 F-box-like tRNA-synt_1b PF00579.20 OAJ05047.1 - 2.2e-59 201.0 0.0 1.6e-58 198.1 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 OAJ05047.1 - 0.12 11.8 0.1 0.31 10.5 0.1 1.7 1 0 0 1 1 1 0 S4 domain DNA_pol_A_exo1 PF01612.15 OAJ05049.1 - 3.5e-13 49.4 0.0 5.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.15 OAJ05050.1 - 2.1e-14 53.3 0.0 8.6e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease DNA_pol_A_exo1 PF01612.15 OAJ05051.1 - 1e-15 57.6 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease GPCR_chapero_1 PF11904.3 OAJ05051.1 - 0.078 12.1 0.1 0.078 12.1 0.1 2.1 2 0 0 2 2 2 0 GPCR-chaperone SRP19 PF01922.12 OAJ05052.1 - 2.6e-18 66.3 0.0 5.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Zn_clus PF00172.13 OAJ05053.1 - 1.6e-07 31.1 9.8 3e-07 30.2 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomerase_RBD PF12009.3 OAJ05054.1 - 9.1e-38 129.2 0.1 2.1e-37 128.0 0.1 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 OAJ05054.1 - 2.7e-12 46.5 0.0 2.2e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo70 PF03081.10 OAJ05056.1 - 2.4e-50 171.3 0.0 1e-48 166.0 0.0 2.2 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Vps52 PF04129.7 OAJ05056.1 - 0.0012 17.4 0.4 0.0028 16.2 0.1 1.6 2 0 0 2 2 2 1 Vps52 / Sac2 family Baculo_PEP_C PF04513.7 OAJ05056.1 - 0.0095 15.7 0.5 0.098 12.4 0.1 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2951 PF11166.3 OAJ05056.1 - 0.024 14.4 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Urocanase PF01175.13 OAJ05056.1 - 0.071 11.1 0.0 0.071 11.1 0.0 1.5 2 0 0 2 2 2 0 Urocanase DUF1419 PF07215.6 OAJ05056.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1419) DDE_Tnp_4 PF13359.1 OAJ05057.1 - 7.1e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-binding PF00249.26 OAJ05058.1 - 1.7e-28 98.3 0.6 3.8e-16 58.8 0.6 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ05058.1 - 2.8e-25 88.1 0.1 1e-15 57.5 0.1 3.8 1 1 2 3 3 3 3 Myb-like DNA-binding domain LMBR1 PF04791.11 OAJ05058.1 - 2.3 6.6 9.0 0.096 11.2 1.4 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein PSP1 PF04468.7 OAJ05059.1 - 4.6e-32 109.8 0.2 7.3e-32 109.2 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Transposase_21 PF02992.9 OAJ05061.1 - 3.7e-07 29.4 0.0 7.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ05061.1 - 1.2e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-HYPF PF07503.7 OAJ05064.1 - 0.24 10.8 2.7 13 5.3 0.2 2.6 3 0 0 3 3 3 0 HypF finger Arch_ATPase PF01637.13 OAJ05071.1 - 1.9e-10 40.8 0.0 5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 OAJ05071.1 - 0.018 14.5 0.7 0.07 12.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ05071.1 - 0.053 13.5 3.9 0.18 11.7 0.1 3.3 2 2 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 OAJ05071.1 - 0.15 12.5 0.2 0.99 9.9 0.1 2.4 1 1 0 1 1 1 0 Miro-like protein Autophagy_N PF03986.8 OAJ05072.1 - 4.5e-45 153.0 0.0 8.4e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 OAJ05072.1 - 2.3e-28 98.1 0.1 4.6e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 OAJ05072.1 - 8.6e-12 43.9 0.3 1.5e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal C2 PF00168.25 OAJ05073.1 - 1.1e-57 191.8 0.4 2.5e-20 72.1 0.0 4.4 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 OAJ05073.1 - 0.0048 17.0 0.0 0.048 13.7 0.0 2.6 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) NT-C2 PF10358.4 OAJ05073.1 - 0.015 14.7 0.0 1.1 8.7 0.0 3.2 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins SpoU_methylase PF00588.14 OAJ05074.1 - 0.0088 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family PhoD PF09423.5 OAJ05075.1 - 0.00057 18.5 0.1 0.0049 15.5 0.1 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase MAGE PF01454.14 OAJ05076.1 - 1.7e-20 73.1 0.0 2.5e-17 62.8 0.0 2.7 2 0 0 2 2 2 2 MAGE family Utp14 PF04615.8 OAJ05076.1 - 1.7 6.7 37.5 0.24 9.5 18.5 2.1 2 0 0 2 2 2 0 Utp14 protein PBP1_TM PF14812.1 OAJ05076.1 - 6.2 7.2 61.3 0.13 12.5 10.4 4.6 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.7 OAJ05078.1 - 0.13 12.9 0.3 0.31 11.7 0.2 1.6 1 0 0 1 1 1 0 Sel1 repeat DAGAT PF03982.8 OAJ05078.1 - 1.3 7.6 3.4 6.9 5.2 0.5 2.2 1 1 1 2 2 2 0 Diacylglycerol acyltransferase Cyclin_N PF00134.18 OAJ05079.1 - 1.1e-36 125.2 0.1 2.2e-36 124.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ05079.1 - 2.7e-10 40.2 0.2 2.7e-10 40.2 0.1 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain BING4CT PF08149.6 OAJ05081.1 - 3.7e-35 119.2 0.0 8.6e-34 114.8 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 OAJ05081.1 - 4e-08 32.8 0.1 4.4e-06 26.3 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 OAJ05081.1 - 0.00042 19.2 0.0 0.00063 18.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region HTH_24 PF13412.1 OAJ05081.1 - 0.063 12.6 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Arm PF00514.18 OAJ05082.1 - 6.4e-92 298.6 13.9 1.6e-12 46.7 0.0 8.6 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 OAJ05082.1 - 1.7e-23 82.6 0.3 7.7e-09 35.7 0.0 6.6 1 1 6 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 OAJ05082.1 - 5.8e-23 80.7 2.3 2.6e-09 37.3 0.0 6.3 5 1 2 7 7 7 4 HEAT-like repeat IBB PF01749.15 OAJ05082.1 - 1.1e-17 63.9 6.3 2.5e-17 62.8 4.4 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 OAJ05082.1 - 1.4e-17 62.1 2.8 7.5e-05 22.4 0.0 7.7 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 OAJ05082.1 - 2e-05 23.8 0.0 0.86 8.6 0.0 3.9 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 OAJ05082.1 - 0.00013 20.4 0.0 0.0013 17.1 0.0 2.3 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.11 OAJ05082.1 - 0.00024 21.2 2.2 0.051 14.0 0.0 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 OAJ05082.1 - 0.013 15.4 0.2 3.6 7.5 0.0 4.2 3 3 2 5 5 5 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 OAJ05082.1 - 0.022 13.0 0.0 0.81 7.8 0.0 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Vps35 PF03635.12 OAJ05082.1 - 0.071 11.2 0.0 0.13 10.3 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Glyco_hydro_32N PF00251.15 OAJ05083.1 - 3.4e-21 75.9 0.0 6.4e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 OAJ05083.1 - 4.9e-06 26.8 0.0 9.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Myc_N PF01056.13 OAJ05084.1 - 0.17 11.0 1.4 0.27 10.3 1.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Mito_carr PF00153.22 OAJ05085.1 - 2.7e-54 180.8 7.9 4.5e-18 64.7 0.1 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2423 PF10338.4 OAJ05086.1 - 3.3e-09 36.5 4.3 3.3e-09 36.5 3.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) BNIP2 PF12496.3 OAJ05086.1 - 0.026 14.7 1.4 0.031 14.4 1.0 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DAO PF01266.19 OAJ05088.1 - 1.8e-31 109.3 0.1 2.8e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ05088.1 - 4.1e-06 26.6 0.4 3.2e-05 23.7 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ05088.1 - 0.0011 18.9 0.1 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Semialdhyde_dh PF01118.19 OAJ05088.1 - 0.022 15.0 0.2 0.27 11.5 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 OAJ05088.1 - 0.12 12.4 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 OAJ05089.1 - 2.7e-40 134.8 19.7 7.5e-10 38.3 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 OAJ05089.1 - 8e-30 103.6 0.0 3e-29 101.7 0.0 2.0 1 1 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.5 OAJ05089.1 - 3.4e-07 29.6 1.5 1.8e-06 27.3 0.6 2.5 2 0 0 2 2 2 1 HIRA B motif Thioredoxin PF00085.15 OAJ05090.1 - 1.1e-29 102.1 0.0 1.3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ05090.1 - 1.3e-09 38.2 0.2 7.7e-09 35.7 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 OAJ05090.1 - 1.2e-06 28.4 0.0 2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 OAJ05090.1 - 9.1e-06 25.2 0.1 1.8e-05 24.3 0.0 1.4 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 OAJ05090.1 - 5.5e-05 22.8 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 OAJ05090.1 - 0.00027 20.4 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 OAJ05090.1 - 0.00089 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 OAJ05090.1 - 0.0022 17.9 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 OAJ05090.1 - 0.024 14.4 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.1 OAJ05090.1 - 0.049 13.1 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2847 PF11009.3 OAJ05090.1 - 0.063 12.8 0.0 0.079 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Got1 PF04178.7 OAJ05091.1 - 3.4e-20 72.3 13.3 3.8e-20 72.1 9.2 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family PH PF00169.24 OAJ05092.1 - 1.1e-39 134.8 0.1 1.5e-19 70.1 0.2 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 OAJ05092.1 - 1.9e-18 66.7 8.8 2.9e-08 33.9 3.0 4.3 3 1 0 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 OAJ05092.1 - 7e-17 61.2 1.0 6.1e-08 32.4 0.2 3.2 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 OAJ05092.1 - 6.5e-12 45.3 4.0 6.2e-07 29.3 0.6 3.1 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 OAJ05092.1 - 4.3e-08 33.3 2.5 0.00023 21.3 0.5 4.0 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 OAJ05092.1 - 9.3e-05 22.3 4.7 0.33 10.8 0.7 3.4 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology PH_7 PF15408.1 OAJ05092.1 - 0.0004 20.2 0.4 0.0032 17.3 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.1 OAJ05092.1 - 0.0019 17.7 2.8 0.12 11.8 0.2 3.4 2 1 1 3 3 3 1 Pleckstrin homology domain Myosin_TH1 PF06017.8 OAJ05092.1 - 0.0044 16.3 0.0 0.43 9.8 0.0 2.9 3 0 0 3 3 3 1 Myosin tail UCR_TM PF02921.9 OAJ05093.1 - 2.8e-20 72.3 2.6 6.1e-20 71.2 1.8 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 OAJ05093.1 - 1.2e-16 60.0 0.1 2.1e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain RasGAP_C PF03836.10 OAJ05094.1 - 6.5e-45 152.3 5.6 6.5e-45 152.3 3.9 2.5 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 OAJ05094.1 - 6.4e-40 136.9 0.0 6.4e-40 136.9 0.0 2.8 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 OAJ05094.1 - 1.9e-24 82.9 25.8 0.0014 18.0 0.0 10.0 9 0 0 9 9 9 9 IQ calmodulin-binding motif CH PF00307.26 OAJ05094.1 - 6.3e-12 45.5 0.0 1.6e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAF-1_p150 PF11600.3 OAJ05094.1 - 0.073 12.4 53.7 0.35 10.2 37.2 2.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAZ_siRNAbind PF12212.3 OAJ05094.1 - 0.1 12.2 0.3 17 5.1 0.0 2.6 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain adh_short PF00106.20 OAJ05095.1 - 1.4e-09 38.0 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ05095.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ05095.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 KR domain DUF3425 PF11905.3 OAJ05097.1 - 9.9e-10 38.4 0.0 3.1e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 OAJ05097.1 - 2.5e-07 30.5 5.1 2.5e-07 30.5 3.6 2.0 3 0 0 3 3 3 1 bZIP transcription factor FTA4 PF13093.1 OAJ05097.1 - 0.038 13.4 0.1 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1691 PF07950.6 OAJ05098.1 - 0.00031 20.6 2.6 0.00031 20.6 1.8 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 OAJ05098.1 - 0.018 14.8 4.5 0.025 14.3 0.2 2.6 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2721 PF11026.3 OAJ05099.1 - 0.038 13.6 0.5 0.043 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) HIG_1_N PF04588.8 OAJ05099.1 - 0.21 11.3 1.4 0.28 10.9 0.2 1.8 1 1 1 2 2 2 0 Hypoxia induced protein conserved region Yip1 PF04893.12 OAJ05100.1 - 1.2e-09 37.9 11.5 2.4e-09 36.9 8.0 1.5 1 0 0 1 1 1 1 Yip1 domain LCM PF04072.9 OAJ05101.1 - 7.7e-16 58.1 0.0 7.3e-15 54.9 0.0 2.1 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Herpes_UL32 PF06070.6 OAJ05101.1 - 1.5 7.1 8.2 2.6 6.4 5.7 1.4 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF427 PF04248.7 OAJ05102.1 - 2.8e-27 94.2 1.5 1.7e-26 91.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF427) UBA PF00627.26 OAJ05103.1 - 0.0021 17.8 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2422 PF10337.4 OAJ05104.1 - 4.7e-61 206.9 3.8 2.4e-60 204.6 2.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ05104.1 - 2.3e-45 154.9 0.2 5.3e-45 153.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ05104.1 - 2.2e-09 37.3 10.1 2.2e-09 37.3 7.0 2.9 3 0 0 3 3 3 1 Fusaric acid resistance protein-like C2 PF00168.25 OAJ05105.1 - 1.8e-18 66.1 0.1 9.7e-15 54.1 0.0 2.4 2 0 0 2 2 2 2 C2 domain Pex2_Pex12 PF04757.9 OAJ05106.1 - 8.6e-47 159.4 3.8 6.9e-29 100.8 0.2 2.0 2 0 0 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 OAJ05106.1 - 1.8e-07 31.0 1.1 2.7e-07 30.5 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ05106.1 - 2.7e-06 26.9 0.5 3.9e-06 26.4 0.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ05106.1 - 0.017 14.9 0.5 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Ring finger domain FdhE PF04216.7 OAJ05106.1 - 0.036 13.7 0.4 0.065 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-C3HC4 PF00097.20 OAJ05106.1 - 0.13 11.9 0.4 0.2 11.3 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ05106.1 - 0.54 10.1 2.9 0.91 9.4 2.0 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Kinesin PF00225.18 OAJ05107.1 - 7.1e-103 343.8 0.1 5.1e-102 341.0 0.1 2.3 1 1 0 1 1 1 1 Kinesin motor domain P4Ha_N PF08336.6 OAJ05107.1 - 0.62 9.8 5.2 0.88 9.3 0.2 3.2 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region UDG PF03167.14 OAJ05108.1 - 6.2e-22 77.7 0.0 2e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Helicase_C PF00271.26 OAJ05109.1 - 7.5e-12 44.9 0.0 2.3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MTHFR PF02219.12 OAJ05109.1 - 0.061 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Kinesin PF00225.18 OAJ05111.1 - 3.4e-71 239.6 0.0 2.7e-43 147.9 0.0 2.4 2 0 0 2 2 2 2 Kinesin motor domain Ribosomal_60s PF00428.14 OAJ05116.1 - 0.023 15.0 3.6 0.049 14.0 2.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein MRC1 PF09444.5 OAJ05116.1 - 0.095 13.0 3.6 0.088 13.1 0.4 2.1 2 0 0 2 2 2 0 MRC1-like domain DUF3435 PF11917.3 OAJ05116.1 - 0.32 9.6 4.2 0.49 9.0 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) FimP PF09766.4 OAJ05117.1 - 0.072 12.1 2.3 0.11 11.5 1.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Ribonucleas_3_3 PF14622.1 OAJ05118.1 - 6.2e-20 71.4 0.1 1.6e-19 70.1 0.1 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like FHA PF00498.21 OAJ05119.1 - 3.6e-16 59.0 0.0 7.9e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain DAO PF01266.19 OAJ05120.1 - 1.3e-43 149.2 0.2 1.1e-42 146.2 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ05120.1 - 2.8e-05 24.0 0.1 0.0001 22.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 OAJ05120.1 - 0.06 13.7 0.0 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 OAJ05120.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 OAJ05120.1 - 0.087 11.8 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 OAJ05120.1 - 0.091 12.8 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 OAJ05120.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 OAJ05120.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Catalase PF00199.14 OAJ05121.1 - 8.6e-163 541.4 1.3 1.1e-162 541.1 0.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 OAJ05121.1 - 3.7e-16 58.7 0.1 1.1e-15 57.1 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF1999 PF09390.5 OAJ05122.1 - 0.05 12.9 4.3 0.22 10.8 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1999) ATP-synt_E PF05680.7 OAJ05122.1 - 4.8 7.1 8.6 23 5.0 6.0 2.0 1 1 0 1 1 1 0 ATP synthase E chain ubiquitin PF00240.18 OAJ05123.1 - 5.3e-09 35.3 0.1 9.9e-09 34.4 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ05123.1 - 5e-06 26.6 0.1 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 OAJ05123.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 OAJ05123.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain YukD PF08817.5 OAJ05123.1 - 0.13 12.8 0.0 0.15 12.6 0.0 1.3 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Glyco_tran_28_C PF04101.11 OAJ05124.1 - 7.4e-21 74.5 0.0 1.1e-20 74.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CheB_methylest PF01339.12 OAJ05124.1 - 0.0019 17.6 0.1 0.0028 17.1 0.1 1.1 1 0 0 1 1 1 1 CheB methylesterase Glyco_trans_1_3 PF13528.1 OAJ05124.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 RAI16-like PF10257.4 OAJ05125.1 - 1.2e-56 192.1 0.0 8.8e-56 189.3 0.0 2.0 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Sigma70_ner PF04546.8 OAJ05125.1 - 0.004 16.7 14.3 0.31 10.6 3.8 3.3 3 0 0 3 3 3 3 Sigma-70, non-essential region VID27 PF08553.5 OAJ05125.1 - 1.2 7.2 3.2 2 6.5 2.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein eIF-3c_N PF05470.7 OAJ05125.1 - 2.8 5.9 3.1 5.2 5.0 2.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RNA_pol_Rpa2_4 PF06883.7 OAJ05128.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain PIF1 PF05970.9 OAJ05130.1 - 1e-18 67.4 0.0 1.7e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ05130.1 - 3e-12 46.5 0.0 1.7e-11 44.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ05130.1 - 1e-07 31.5 0.2 4.5e-07 29.5 0.2 2.1 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ05130.1 - 1.1e-05 25.2 0.1 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ05130.1 - 0.0046 16.9 0.0 0.022 14.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 OAJ05130.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 OAJ05130.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Enolase_C PF00113.17 OAJ05130.1 - 0.47 9.3 0.0 0.86 8.5 0.0 1.3 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Pox_A32 PF04665.7 OAJ05130.1 - 0.64 9.2 0.0 1.2 8.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Cyclin_N PF00134.18 OAJ05131.1 - 7.8e-17 61.0 0.1 3.2e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ05131.1 - 4.2e-15 55.7 0.4 9.8e-13 48.0 0.1 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain DUF3203 PF11462.3 OAJ05131.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3203) Histone PF00125.19 OAJ05132.1 - 1.1e-07 31.9 0.1 1.9e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ05132.1 - 0.006 16.7 0.1 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF4095 PF13338.1 OAJ05132.1 - 0.019 15.1 0.4 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) TAF PF02969.12 OAJ05132.1 - 0.031 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 OAJ05132.1 - 0.037 13.2 0.4 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 OAJ05132.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF4611 PF15387.1 OAJ05132.1 - 0.1 12.7 0.0 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Bromo_TP PF07524.8 OAJ05132.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.18 OAJ05132.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Baculo_PEP_C PF04513.7 OAJ05133.1 - 0.033 14.0 0.6 0.39 10.5 0.0 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 OAJ05133.1 - 0.07 13.5 0.4 0.21 11.9 0.1 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HK97-gp10_like PF04883.7 OAJ05135.1 - 0.032 15.1 1.2 0.28 12.1 0.0 2.6 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Collagen PF01391.13 OAJ05135.1 - 5.8 6.5 23.9 6 6.5 6.5 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Mito_fiss_reg PF05308.6 OAJ05135.1 - 9.2 5.5 9.7 17 4.6 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Ndc80_HEC PF03801.8 OAJ05136.1 - 8.8e-35 119.5 0.0 1.8e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family DUF948 PF06103.6 OAJ05136.1 - 0.034 14.0 11.2 0.074 12.9 0.1 4.0 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF720 PF05302.6 OAJ05136.1 - 0.91 9.2 9.0 0.23 11.2 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF720) SRP9-21 PF05486.7 OAJ05137.1 - 2.5e-17 62.3 0.3 3.3e-17 62.0 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CPSase_L_D3 PF02787.14 OAJ05138.1 - 0.036 13.8 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_AsnC-type PF13404.1 OAJ05138.1 - 0.092 12.3 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PHD PF00628.24 OAJ05139.1 - 0.00052 19.6 9.5 0.0016 18.0 6.6 1.8 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 OAJ05139.1 - 3.1 7.5 7.5 0.84 9.4 2.4 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DDE_3 PF13358.1 OAJ05140.1 - 1.2e-12 47.7 0.0 1.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ05140.1 - 1.3e-06 28.5 0.1 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ05140.1 - 1.1e-05 26.1 0.7 2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 OAJ05140.1 - 0.0031 17.3 2.3 0.083 12.7 0.0 2.9 4 0 0 4 4 4 1 Helix-turn-helix domain of resolvase Transposase_mut PF00872.13 OAJ05140.1 - 0.061 11.8 0.2 4.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Transposase, Mutator family AT_hook PF02178.14 OAJ05143.1 - 3.2 7.7 9.1 7 6.6 6.3 1.6 1 0 0 1 1 1 0 AT hook motif Nop14 PF04147.7 OAJ05144.1 - 0.066 11.1 5.8 0.07 11.0 4.0 1.0 1 0 0 1 1 1 0 Nop14-like family HTH_21 PF13276.1 OAJ05145.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 HTH-like domain DUF2620 PF10941.3 OAJ05147.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2620 LSM PF01423.17 OAJ05149.1 - 4.6e-16 58.1 1.3 5.9e-16 57.7 0.9 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 OAJ05149.1 - 0.1 12.3 1.0 0.2 11.3 0.7 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 OAJ05149.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) API5 PF05918.6 OAJ05149.1 - 4.6 5.6 6.5 5.6 5.3 4.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Sigma70_r4 PF04545.11 OAJ05150.1 - 0.0045 16.2 1.1 0.0049 16.1 0.1 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_psq PF05225.11 OAJ05150.1 - 0.044 13.3 0.1 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Hemerythrin PF01814.18 OAJ05151.1 - 2e-09 37.6 5.0 2e-09 37.6 3.5 2.0 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Clathrin PF00637.15 OAJ05151.1 - 0.038 13.6 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS XPG_I PF00867.13 OAJ05152.1 - 1.6e-26 92.1 0.0 4.2e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 OAJ05152.1 - 2.5e-25 88.6 0.0 5.7e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 OAJ05152.1 - 0.0036 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 OAJ05152.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CN_hydrolase PF00795.17 OAJ05153.1 - 1.4e-29 102.7 0.0 1.9e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.17 OAJ05154.1 - 1.7e-32 110.8 0.0 6.2e-19 67.3 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05154.1 - 3.6e-23 81.3 0.1 8.9e-14 51.2 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05154.1 - 8.3e-12 44.7 0.0 1.8e-06 27.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 OAJ05154.1 - 3.7e-11 42.5 0.1 0.00019 21.0 0.0 2.6 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 OAJ05154.1 - 0.046 13.4 0.1 16 5.3 0.1 2.6 2 0 0 2 2 2 0 Limkain b1 TMPIT PF07851.8 OAJ05155.1 - 4.6 6.2 3.2 12 4.9 2.2 1.6 1 0 0 1 1 1 0 TMPIT-like protein UBX PF00789.15 OAJ05156.1 - 3.2e-11 43.1 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain Exo_endo_phos PF03372.18 OAJ05157.1 - 6.2e-28 98.4 0.1 1.1e-27 97.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF605 PF04652.11 OAJ05157.1 - 4.5 6.5 16.6 0.45 9.8 7.9 1.8 2 0 0 2 2 2 0 Vta1 like F-box-like PF12937.2 OAJ05160.1 - 0.00056 19.5 0.6 0.0012 18.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like Pyrid_oxidase_2 PF13883.1 OAJ05160.1 - 0.14 11.9 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase E1-E2_ATPase PF00122.15 OAJ05162.1 - 3.9e-64 215.8 3.8 3.9e-64 215.8 2.6 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ05162.1 - 1.1e-31 109.7 4.7 1.1e-31 109.7 3.3 3.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ05162.1 - 6.5e-29 101.8 0.0 7.2e-28 98.4 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ05162.1 - 5e-18 64.8 0.1 1.1e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 OAJ05162.1 - 8e-15 54.0 0.0 8e-15 54.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 OAJ05162.1 - 3.5e-13 50.1 0.0 7.6e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ05162.1 - 2.1e-06 27.5 0.2 1.8e-05 24.4 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP19 PF01922.12 OAJ05162.1 - 0.12 12.9 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 SRP19 protein Pneumo_att_G PF05539.6 OAJ05162.1 - 0.75 9.1 3.5 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G Tyr_Deacylase PF02580.11 OAJ05163.1 - 2.8e-46 157.1 0.2 3.4e-45 153.5 0.1 1.9 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Dak1 PF02733.12 OAJ05164.1 - 6.1e-91 304.3 0.0 8.5e-91 303.9 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 OAJ05164.1 - 1.1e-35 122.8 3.1 2.2e-35 121.9 2.1 1.4 1 0 0 1 1 1 1 DAK2 domain DUF4261 PF14080.1 OAJ05164.1 - 0.026 14.3 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Peptidase_S28 PF05577.7 OAJ05165.1 - 3.2e-38 131.4 0.9 8.7e-34 116.8 0.0 2.8 2 1 1 3 3 3 2 Serine carboxypeptidase S28 GPI-anchored PF10342.4 OAJ05167.1 - 6.6e-09 36.1 1.9 6.8e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3876 PF12992.2 OAJ05167.1 - 0.13 12.2 0.1 12 5.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) NPV_P10 PF05531.7 OAJ05168.1 - 0.15 12.3 1.0 0.28 11.4 0.2 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein KRTAP PF11759.3 OAJ05169.1 - 0.24 11.6 5.4 0.44 10.8 3.7 1.4 1 1 0 1 1 1 0 Keratin-associated matrix SKN1 PF03935.10 OAJ05170.1 - 3.4e-178 592.9 1.3 4.5e-178 592.5 0.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ05170.1 - 2.9e-05 23.4 0.3 0.01 15.1 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 16 CGI-121 PF08617.5 OAJ05171.1 - 1.8e-25 89.4 0.0 3.6e-25 88.5 0.0 1.5 1 1 0 1 1 1 1 Kinase binding protein CGI-121 RRN3 PF05327.6 OAJ05172.1 - 0.17 9.9 2.2 0.25 9.4 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribonuclease_3 PF00636.21 OAJ05173.1 - 2.1e-10 41.0 0.0 5.3e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ05173.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like PBP1_TM PF14812.1 OAJ05174.1 - 9.3 6.6 13.6 2.4 8.4 0.1 4.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2419 PF10343.4 OAJ05175.1 - 1.1e-05 24.8 0.0 0.0027 16.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) PQQ_3 PF13570.1 OAJ05177.1 - 0.039 14.2 0.0 1.3 9.4 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain Pyr_redox_2 PF07992.9 OAJ05178.1 - 3.9e-23 82.4 0.0 9.3e-11 41.9 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ05178.1 - 1e-12 48.2 0.0 5.8e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ05178.1 - 9.1e-07 29.1 0.0 0.0063 16.5 0.0 3.1 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 OAJ05178.1 - 0.003 17.5 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_7 PF13241.1 OAJ05178.1 - 0.019 15.2 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 OAJ05178.1 - 0.064 12.0 0.0 5.8 5.6 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 OAJ05178.1 - 0.072 12.0 0.0 2.1 7.1 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 OAJ05178.1 - 0.17 10.7 0.8 4.7 6.0 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein ACPS PF01648.15 OAJ05179.1 - 3.1e-09 36.6 0.0 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Phage_integrase PF00589.17 OAJ05180.1 - 1.8e-06 27.7 0.0 3.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family DUF2964 PF11177.3 OAJ05181.1 - 0.26 11.2 0.1 0.52 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) SKI PF01202.17 OAJ05182.1 - 1.1e-09 38.3 0.7 1.3e-05 25.1 0.0 2.9 1 1 0 2 2 2 2 Shikimate kinase AAA_17 PF13207.1 OAJ05182.1 - 1.1e-08 35.8 0.5 3.8e-08 34.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ05182.1 - 7e-07 29.6 1.2 2e-05 24.9 0.8 2.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ05182.1 - 2.9e-06 27.2 0.8 0.00031 20.6 0.6 2.7 1 1 0 1 1 1 1 AAA domain Spore_coat_CotO PF14153.1 OAJ05182.1 - 0.0051 16.2 0.7 0.006 16.0 0.5 1.2 1 0 0 1 1 1 1 Spore coat protein CotO APS_kinase PF01583.15 OAJ05182.1 - 0.0071 16.0 0.3 0.5 10.0 0.0 2.3 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.9 OAJ05182.1 - 0.0071 16.0 0.1 0.58 9.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 OAJ05182.1 - 0.0076 16.1 1.2 0.11 12.3 0.0 2.7 2 1 1 3 3 3 1 Cytidylate kinase-like family AAA_25 PF13481.1 OAJ05182.1 - 0.01 15.2 0.2 0.084 12.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ05182.1 - 0.015 15.3 1.4 0.022 14.7 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 OAJ05182.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ05182.1 - 0.033 14.3 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ05182.1 - 0.068 12.3 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ05182.1 - 0.086 13.1 4.5 0.35 11.1 3.1 2.0 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 OAJ05182.1 - 0.12 12.5 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ05182.1 - 0.61 10.0 5.2 3.5 7.5 3.6 2.4 1 1 0 1 1 1 0 AAA ATPase domain CGI-121 PF08617.5 OAJ05183.1 - 7.3e-28 97.2 0.0 1.3e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 SRP-alpha_N PF04086.8 OAJ05184.1 - 2.9e-46 158.0 0.0 5.7e-46 157.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 OAJ05184.1 - 7.2e-46 156.1 0.0 8.6e-29 100.3 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain CbiA PF01656.18 OAJ05184.1 - 1.5e-07 31.0 0.1 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 OAJ05184.1 - 1.4e-06 28.3 0.0 4.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 OAJ05184.1 - 0.0025 16.6 0.0 0.26 10.0 0.0 2.6 3 0 0 3 3 3 1 ArgK protein AAA_22 PF13401.1 OAJ05184.1 - 0.0057 16.7 0.1 0.028 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 OAJ05184.1 - 0.011 15.4 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 OAJ05184.1 - 0.034 14.1 4.4 0.093 12.7 0.0 3.0 2 2 1 3 3 3 0 AAA ATPase domain Fer4_NifH PF00142.13 OAJ05184.1 - 0.089 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Sigma70_ner PF04546.8 OAJ05184.1 - 1.2 8.7 4.7 2.3 7.7 3.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Iso_dh PF00180.15 OAJ05185.1 - 2.9e-117 391.5 0.0 3.3e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.7 OAJ05185.1 - 0.08 12.6 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 YebG protein Ribonuclease_3 PF00636.21 OAJ05186.1 - 3.3e-06 27.5 0.0 5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain DUF2034 PF10356.4 OAJ05187.1 - 5.9e-18 64.6 2.7 6.8e-16 57.9 0.1 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 OAJ05187.1 - 4.4e-06 26.4 0.0 1.8e-05 24.5 0.0 2.0 2 1 0 2 2 2 1 Restriction endonuclease DUF1708 PF08101.6 OAJ05188.1 - 2.8e-09 36.3 0.1 3.5e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 OAJ05188.1 - 0.0016 18.0 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Ribonuclease_3 PF00636.21 OAJ05189.1 - 3.6e-07 30.6 0.0 2.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonuclease_3 PF00636.21 OAJ05190.1 - 0.00038 20.8 0.0 0.00049 20.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease III domain Ribonuclease_3 PF00636.21 OAJ05191.1 - 0.0093 16.4 0.0 0.025 15.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 OAJ05191.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease-III-like Med3 PF11593.3 OAJ05192.1 - 5.8 6.0 20.1 0.014 14.7 4.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DDE_Tnp_4 PF13359.1 OAJ05193.1 - 1.1e-30 106.3 0.0 1.4e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 OAJ05193.1 - 3.2e-07 30.1 0.0 5.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Transposase DDE domain Plant_tran PF04827.9 OAJ05193.1 - 0.00022 20.6 0.0 0.0047 16.3 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein DUF4112 PF13430.1 OAJ05196.1 - 2.8e-27 94.7 0.1 3.7e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) SKN1 PF03935.10 OAJ05197.1 - 1.1e-177 591.2 2.5 1.4e-177 590.8 1.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ05197.1 - 8e-06 25.2 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 UBX PF00789.15 OAJ05198.1 - 5.3e-07 29.6 0.0 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 OAJ05198.1 - 0.0094 15.7 2.1 0.22 11.4 0.0 3.3 4 0 0 4 4 3 1 UBA/TS-N domain DUF572 PF04502.8 OAJ05198.1 - 0.013 14.7 18.4 0.017 14.3 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2_2 PF12756.2 OAJ05198.1 - 0.061 13.4 0.3 0.061 13.4 0.2 1.9 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_5 PF13719.1 OAJ05198.1 - 0.092 12.3 0.3 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 OAJ05198.1 - 0.096 12.4 0.2 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain c-SKI_SMAD_bind PF08782.5 OAJ05198.1 - 0.11 12.6 0.5 0.33 11.0 0.1 2.0 1 1 1 2 2 2 0 c-SKI Smad4 binding domain zf-C2H2 PF00096.21 OAJ05198.1 - 0.16 12.3 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rtf2 PF04641.7 OAJ05198.1 - 0.8 8.8 20.4 1.2 8.2 14.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger APG6 PF04111.7 OAJ05198.1 - 1.1 8.2 18.9 1.5 7.8 13.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PLRV_ORF5 PF01690.12 OAJ05198.1 - 2.3 7.2 9.6 2.7 7.0 6.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2344 PF10105.4 OAJ05198.1 - 6.7 6.1 10.6 9.8 5.6 7.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Asp-B-Hydro_N PF05279.6 OAJ05198.1 - 9.3 6.0 22.3 13 5.5 15.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BAR_2 PF10455.4 OAJ05199.1 - 1.7e-43 148.5 0.0 3.2e-43 147.7 0.0 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 OAJ05199.1 - 2.2e-12 47.0 1.4 4.2e-10 39.5 0.2 2.1 2 0 0 2 2 2 2 BAR domain Phycobilisome PF00502.14 OAJ05199.1 - 0.052 13.2 2.1 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Phycobilisome protein ATG16 PF08614.6 OAJ05199.1 - 0.33 10.7 5.9 0.52 10.1 0.9 2.4 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 OAJ05199.1 - 1.3 9.1 7.1 2.6 8.1 0.0 3.1 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain F-box-like PF12937.2 OAJ05209.1 - 0.00018 21.1 1.5 0.00062 19.4 1.1 1.9 1 0 0 1 1 1 1 F-box-like HEAT_EZ PF13513.1 OAJ05209.1 - 0.068 13.6 0.1 0.32 11.5 0.1 2.3 1 0 0 1 1 1 0 HEAT-like repeat F-box PF00646.28 OAJ05209.1 - 0.86 9.3 4.2 0.78 9.4 0.9 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 OAJ05211.1 - 0.00014 21.4 1.1 0.00038 20.1 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ05211.1 - 0.05 13.2 1.0 0.2 11.3 0.7 2.0 1 0 0 1 1 1 0 F-box domain AAR2 PF05282.6 OAJ05214.1 - 6.3e-42 143.8 0.0 8.7e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein zf-RING_2 PF13639.1 OAJ05215.1 - 9.2e-08 31.8 6.8 1.7e-07 30.9 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 OAJ05215.1 - 2.1e-06 27.7 1.0 4.7e-06 26.6 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 OAJ05215.1 - 0.0015 18.3 1.5 0.003 17.3 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 OAJ05215.1 - 0.0068 16.3 3.6 0.016 15.1 2.5 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 OAJ05215.1 - 0.0071 16.3 5.9 0.016 15.2 4.1 1.7 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 OAJ05215.1 - 0.011 15.3 8.1 0.02 14.5 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PNMA PF14893.1 OAJ05215.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 PNMA C1_1 PF00130.17 OAJ05215.1 - 0.29 10.9 3.4 0.58 9.9 2.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TIMELESS_C PF05029.8 OAJ05215.1 - 0.31 9.9 1.4 0.53 9.1 0.9 1.3 1 0 0 1 1 1 0 Timeless protein C terminal region Nucleoplasmin PF03066.10 OAJ05215.1 - 0.8 9.2 4.5 1.7 8.1 3.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF4206 PF13901.1 OAJ05215.1 - 1.6 8.2 3.5 3.5 7.1 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) Cnd2 PF05786.9 OAJ05215.1 - 1.9 6.8 2.6 3.3 6.1 1.8 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 PHD PF00628.24 OAJ05215.1 - 2.3 7.9 5.1 4.2 7.1 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 OAJ05215.1 - 3.7 7.3 5.1 6.6 6.4 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CobT PF06213.7 OAJ05215.1 - 3.9 6.5 7.7 0.96 8.5 2.6 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 OAJ05215.1 - 4.6 5.8 12.7 18 3.9 6.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Cullin PF00888.17 OAJ05217.1 - 6.8e-104 348.5 0.0 1.8e-103 347.1 0.0 1.6 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 OAJ05217.1 - 1.3e-20 72.9 0.4 3.9e-20 71.4 0.3 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain BTB PF00651.26 OAJ05218.1 - 4.2e-06 26.7 0.0 0.0099 15.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Polyketide_cyc PF03364.15 OAJ05219.1 - 1.2e-24 86.7 0.0 2.6e-24 85.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 OAJ05219.1 - 0.0007 19.7 0.3 0.013 15.6 0.2 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SynMuv_product PF06047.6 OAJ05220.1 - 2.7e-47 158.8 4.2 2.7e-47 158.8 2.9 1.9 2 0 0 2 2 2 1 Ras-induced vulval development antagonist DUF4611 PF15387.1 OAJ05223.1 - 2.7 8.2 0.0 2.7 8.2 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Glyco_transf_28 PF03033.15 OAJ05224.1 - 1.4e-25 89.7 0.0 3e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 OAJ05224.1 - 1.3e-05 24.6 0.0 0.37 10.3 0.0 3.0 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 OAJ05224.1 - 0.0037 15.8 0.0 0.0057 15.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 OAJ05224.1 - 0.014 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 PH domain Arteri_Gl PF00951.13 OAJ05224.1 - 0.39 10.2 0.1 1 8.9 0.1 1.6 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein HEAT_2 PF13646.1 OAJ05226.1 - 2.6e-24 85.3 14.6 4.2e-13 49.3 0.5 4.3 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 OAJ05226.1 - 1e-11 43.8 2.2 0.17 12.0 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_PBS PF03130.11 OAJ05226.1 - 1.7e-11 43.4 3.7 0.0023 18.2 0.0 7.1 7 0 0 7 7 7 2 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 OAJ05226.1 - 3.2e-07 30.6 8.4 0.092 13.2 0.0 5.9 5 2 1 6 6 6 2 HEAT-like repeat Arm PF00514.18 OAJ05226.1 - 0.01 15.6 0.0 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF3636 PF12331.3 OAJ05228.1 - 0.14 11.7 0.1 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) PHD PF00628.24 OAJ05229.1 - 1.8e-13 49.9 19.8 1.4e-08 34.2 6.1 2.9 3 0 0 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 OAJ05229.1 - 3.6 7.8 7.5 0.3 11.2 1.5 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain XRCC4 PF06632.7 OAJ05229.1 - 7.2 5.3 7.2 3 6.6 0.1 2.4 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Peptidase_M41 PF01434.13 OAJ05230.1 - 5.5e-71 238.4 0.5 5.5e-71 238.4 0.3 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 OAJ05230.1 - 6.5e-42 142.8 0.0 1.7e-41 141.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 OAJ05230.1 - 8.3e-12 45.2 1.1 1.6e-11 44.3 0.0 2.1 2 1 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.1 OAJ05230.1 - 0.00024 21.2 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ05230.1 - 0.00088 18.9 0.2 0.0046 16.6 0.1 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ05230.1 - 0.0025 17.2 1.0 0.025 13.9 0.3 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.8 OAJ05230.1 - 0.0059 15.3 0.0 0.0097 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 OAJ05230.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 OAJ05230.1 - 0.0092 15.7 0.1 0.063 13.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ05230.1 - 0.014 15.3 0.2 0.13 12.2 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 OAJ05230.1 - 0.016 16.0 0.0 0.056 14.2 0.0 2.0 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 OAJ05230.1 - 0.019 14.0 0.0 0.048 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 OAJ05230.1 - 0.025 13.6 0.0 0.056 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ05230.1 - 0.16 11.1 0.2 0.36 9.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EF-hand_7 PF13499.1 OAJ05231.1 - 1e-05 25.5 0.4 3.6e-05 23.7 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 OAJ05231.1 - 2.1e-05 24.0 0.3 0.073 12.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 OAJ05231.1 - 3.6e-05 22.9 0.2 0.23 10.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 OAJ05231.1 - 4.1e-05 22.5 0.6 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 OAJ05231.1 - 4.4 7.3 9.2 2.5 8.1 0.1 3.8 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L32p PF01783.18 OAJ05232.1 - 2.9e-13 49.7 6.6 6.2e-13 48.7 4.6 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF164 PF02591.10 OAJ05232.1 - 0.07 12.9 3.3 2.2 8.1 0.2 2.5 2 1 1 3 3 3 0 Putative zinc ribbon domain Peptidase_M23 PF01551.17 OAJ05234.1 - 2.4e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 Sigma70_ner PF04546.8 OAJ05235.1 - 8.5 5.9 16.7 6.8 6.2 0.1 3.2 4 0 0 4 4 4 0 Sigma-70, non-essential region F-box-like PF12937.2 OAJ05236.1 - 0.025 14.3 0.2 0.081 12.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like KH_1 PF00013.24 OAJ05237.1 - 3.3e-31 106.7 2.0 1.2e-09 37.6 0.0 5.8 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 OAJ05237.1 - 2.4e-21 74.9 2.2 3.6e-07 29.6 0.1 4.9 4 0 0 4 4 4 4 KH domain DUF4407 PF14362.1 OAJ05237.1 - 2.7 6.8 17.8 1.6 7.6 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_ATPase PF09818.4 OAJ05238.1 - 6.3e-139 463.4 0.0 1.1e-125 419.7 0.0 2.0 2 0 0 2 2 2 2 Predicted ATPase of the ABC class HD_assoc PF13286.1 OAJ05238.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphohydrolase-associated domain DUF2813 PF11398.3 OAJ05238.1 - 0.12 11.4 0.7 2.4 7.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) UQ_con PF00179.21 OAJ05239.1 - 1.4e-16 60.1 0.0 1.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RhoGAP PF00620.22 OAJ05240.1 - 3e-45 153.5 0.0 1.2e-44 151.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 OAJ05240.1 - 6.2e-13 48.6 16.2 2.8e-08 33.6 4.3 3.4 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 OAJ05240.1 - 2e-06 27.4 7.3 2e-06 27.4 5.1 3.5 3 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Nup88 PF10168.4 OAJ05240.1 - 0.0021 15.9 1.0 0.0043 14.9 0.7 1.4 1 0 0 1 1 1 1 Nuclear pore component Zip PF02535.17 OAJ05240.1 - 0.34 9.8 3.9 0.81 8.6 2.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter FHA PF00498.21 OAJ05241.1 - 0.002 18.1 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain DDE_1 PF03184.14 OAJ05242.1 - 1.1e-29 103.1 0.5 1.6e-29 102.5 0.4 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 OAJ05242.1 - 0.00017 21.3 0.1 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Mak10 PF04112.8 OAJ05242.1 - 0.037 13.2 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF2360 PF10152.4 OAJ05242.1 - 4.4 7.5 7.0 12 6.1 4.8 2.0 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DDE_3 PF13358.1 OAJ05243.1 - 3e-14 52.9 0.0 5.8e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 OAJ05243.1 - 2e-12 46.9 1.7 4.2e-12 45.9 0.8 1.8 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 OAJ05243.1 - 1.2e-06 28.6 1.4 4e-06 26.9 0.6 2.1 1 1 1 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ05243.1 - 6.5e-05 23.6 2.7 0.00046 20.9 0.7 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 OAJ05243.1 - 0.081 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-C_C PF11699.3 OAJ05246.1 - 2.3e-28 97.9 0.5 3.7e-28 97.3 0.3 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 OAJ05246.1 - 0.00019 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 OAJ05246.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain 60KD_IMP PF02096.15 OAJ05247.1 - 4.1e-16 59.2 0.0 1.7e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein Polysacc_deac_1 PF01522.16 OAJ05248.1 - 5.1e-29 100.4 0.0 9.3e-29 99.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 2OG-FeII_Oxy_2 PF13532.1 OAJ05249.1 - 1.2e-26 93.7 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ05249.1 - 0.00027 21.1 0.0 0.00062 20.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 OAJ05250.1 - 3.8e-63 213.6 0.0 5.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.22 OAJ05254.1 - 2.6e-32 111.9 0.0 3.9e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ05254.1 - 8e-14 52.1 0.0 1.9e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ05254.1 - 5.9e-11 42.0 0.0 1.3e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_3 PF13456.1 OAJ05254.1 - 0.0002 21.0 0.0 0.00051 19.7 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like MoaE PF02391.12 OAJ05255.1 - 4.7e-26 90.8 0.0 2.7e-25 88.4 0.0 1.9 1 1 0 1 1 1 1 MoaE protein TOM13 PF08219.6 OAJ05256.1 - 1.6e-11 43.8 0.1 4.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 BUD22 PF09073.5 OAJ05256.1 - 0.0025 16.9 1.4 0.0032 16.6 1.0 1.2 1 0 0 1 1 1 1 BUD22 LAT PF15234.1 OAJ05256.1 - 0.0098 15.3 0.9 0.017 14.6 0.7 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells PBP1_TM PF14812.1 OAJ05256.1 - 0.013 15.7 6.8 0.026 14.8 4.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.8 OAJ05256.1 - 0.024 14.5 2.8 0.039 13.8 2.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 OAJ05256.1 - 0.032 13.7 5.9 0.046 13.2 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 OAJ05256.1 - 0.046 11.6 4.1 0.05 11.5 2.8 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ05256.1 - 0.074 12.2 6.0 0.097 11.9 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 OAJ05256.1 - 0.11 12.2 6.7 0.14 11.8 4.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 OAJ05256.1 - 0.16 12.2 11.3 0.29 11.3 7.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTV_NS2 PF04514.7 OAJ05256.1 - 0.38 9.5 4.2 0.48 9.2 2.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sigma70_ner PF04546.8 OAJ05256.1 - 0.45 10.0 6.8 0.74 9.3 4.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleo_P87 PF07267.6 OAJ05256.1 - 2.3 6.7 4.6 3 6.4 3.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 OAJ05256.1 - 3.9 5.3 6.1 5.2 4.9 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 OAJ05256.1 - 4.6 5.6 11.0 7.3 4.9 7.7 1.2 1 0 0 1 1 1 0 Daxx Family RXT2_N PF08595.6 OAJ05256.1 - 8.1 6.2 6.7 13 5.5 4.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RRM_1 PF00076.17 OAJ05257.1 - 1.2e-15 56.9 0.0 1.6e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05257.1 - 4.6e-13 48.9 0.0 6.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05257.1 - 8.8e-09 35.0 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ05257.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 RNA binding motif Mito_carr PF00153.22 OAJ05258.1 - 1.1e-36 124.4 0.9 5.5e-14 51.6 0.1 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Rep_fac_C PF08542.6 OAJ05259.1 - 3.3e-20 71.8 0.0 6.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 OAJ05259.1 - 2.2e-12 47.3 0.0 5.8e-12 45.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ05259.1 - 1.2e-11 44.5 0.0 5.1e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 OAJ05259.1 - 1.2e-07 31.8 0.1 1.8e-06 28.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 OAJ05259.1 - 1.6e-06 27.0 0.0 0.0013 17.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 OAJ05259.1 - 1.7e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 OAJ05259.1 - 5.5e-06 26.3 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ05259.1 - 1.4e-05 25.2 0.1 0.0044 17.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 OAJ05259.1 - 5.5e-05 22.3 0.0 0.00014 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 OAJ05259.1 - 5.8e-05 22.6 0.0 0.021 14.2 0.0 2.8 1 1 2 3 3 3 1 AAA-like domain ArgK PF03308.11 OAJ05259.1 - 0.00054 18.8 0.0 0.0011 17.7 0.0 1.6 1 0 0 1 1 1 1 ArgK protein Viral_helicase1 PF01443.13 OAJ05259.1 - 0.0014 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 OAJ05259.1 - 0.0016 18.1 0.0 0.04 13.6 0.0 2.3 1 1 1 2 2 2 1 NTPase AAA_19 PF13245.1 OAJ05259.1 - 0.0021 17.7 0.0 0.006 16.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_31 PF13614.1 OAJ05259.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ05259.1 - 0.0068 15.8 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 OAJ05259.1 - 0.011 14.9 0.0 0.11 11.6 0.0 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 OAJ05259.1 - 0.015 14.7 0.7 0.066 12.6 0.0 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain KTI12 PF08433.5 OAJ05259.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MipZ PF09140.6 OAJ05259.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ MobB PF03205.9 OAJ05259.1 - 0.019 14.6 0.2 0.3 10.8 0.0 2.3 1 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 OAJ05259.1 - 0.021 14.3 0.5 0.099 12.2 0.0 2.3 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.8 OAJ05259.1 - 0.031 13.2 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 OAJ05259.1 - 0.045 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 OAJ05259.1 - 0.065 12.6 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_11 PF13086.1 OAJ05259.1 - 0.096 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ05259.1 - 0.13 11.7 0.1 0.86 9.0 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase SNF2_N PF00176.18 OAJ05260.1 - 1.6e-55 188.0 0.0 1.6e-55 188.0 0.0 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ05260.1 - 9.3e-16 57.4 0.0 5.8e-15 54.9 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ05260.1 - 4.3e-09 35.9 9.3 7.3e-05 22.3 0.1 3.7 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 OAJ05260.1 - 5.2e-07 29.2 5.7 0.0099 15.5 0.1 2.8 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 OAJ05260.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Tim10_DDP PF02953.10 OAJ05261.1 - 4.4e-23 80.3 0.8 5.2e-23 80.1 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger QCR10 PF09796.4 OAJ05262.1 - 1.2e-22 79.2 0.6 1.6e-22 78.8 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 OAJ05262.1 - 0.031 13.9 2.7 0.065 12.9 1.9 1.7 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Ribosomal_S17 PF00366.15 OAJ05263.1 - 6.5e-31 106.1 0.7 1e-30 105.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Mito_carr PF00153.22 OAJ05264.1 - 5.6e-65 215.1 0.2 1.6e-20 72.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 OAJ05264.1 - 0.071 12.9 0.4 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 UcrQ family PLDc_2 PF13091.1 OAJ05265.1 - 6.8e-14 51.7 0.0 3.2e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 PLD-like domain DUF1295 PF06966.7 OAJ05267.1 - 1.2e-42 145.8 0.0 2.7e-42 144.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 OAJ05267.1 - 0.022 14.9 0.0 0.083 13.1 0.0 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Acyl-CoA_dh_N PF02771.11 OAJ05267.1 - 0.14 12.7 0.1 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Chorismate_synt PF01264.16 OAJ05268.1 - 6.7e-131 435.8 0.1 1.2e-130 434.9 0.1 1.4 1 1 0 1 1 1 1 Chorismate synthase PAS_9 PF13426.1 OAJ05269.1 - 1.1e-19 70.6 0.0 8.7e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ05269.1 - 5.8e-08 32.5 0.0 2.1e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 OAJ05269.1 - 8.8e-06 25.7 0.0 0.00015 21.7 0.0 2.6 2 1 0 2 2 2 1 PAS fold RGS PF00615.14 OAJ05269.1 - 9.3e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_3 PF08447.6 OAJ05269.1 - 0.019 15.0 0.0 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.1 OAJ05269.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.9 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.1 OAJ05270.1 - 2.9e-19 69.3 0.0 9e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 OAJ05270.1 - 3.9e-08 33.0 0.0 1.7e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 PAS fold RGS PF00615.14 OAJ05270.1 - 5e-07 29.8 0.1 1.3e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Regulator of G protein signaling domain PAS_4 PF08448.5 OAJ05270.1 - 4.2e-05 23.5 0.0 0.00023 21.1 0.0 2.2 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.6 OAJ05270.1 - 0.01 15.8 0.0 0.079 13.0 0.0 2.3 2 0 0 2 2 2 0 PAS fold TGS PF02824.16 OAJ05271.1 - 3.3e-23 81.2 0.0 6.2e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAJ05271.1 - 1.5e-18 66.8 0.1 3.9e-18 65.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ05271.1 - 8.6e-10 38.0 0.1 2.7e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ05271.1 - 0.00026 20.8 0.1 0.08 12.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 OAJ05271.1 - 0.0074 15.7 0.7 7.4 5.9 0.0 3.5 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 OAJ05271.1 - 0.012 16.0 0.0 0.035 14.6 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 OAJ05271.1 - 0.018 13.7 0.7 0.042 12.6 0.1 1.8 2 0 0 2 2 2 0 ArgK protein DDHD PF02862.12 OAJ05273.1 - 1.3e-29 103.6 0.0 1.3e-29 103.6 0.0 3.9 3 2 0 3 3 3 2 DDHD domain Sds3 PF08598.6 OAJ05274.1 - 2.1e-22 79.6 4.8 2.1e-22 79.6 3.4 2.0 2 1 0 2 2 2 1 Sds3-like PI3K_1B_p101 PF10486.4 OAJ05274.1 - 0.037 11.6 1.0 0.065 10.8 0.7 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIB PF00382.14 OAJ05275.1 - 1.9e-26 91.6 0.1 1.2e-17 63.5 0.1 3.0 2 1 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 OAJ05275.1 - 3.5e-22 78.4 5.3 3.5e-22 78.4 3.7 4.6 5 1 0 5 5 5 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 OAJ05275.1 - 9.5e-07 28.0 1.0 1.9e-06 27.0 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 OAJ05275.1 - 1.6e-06 27.7 0.1 0.052 13.1 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain DNA_RNApol_7kD PF03604.8 OAJ05275.1 - 0.046 13.1 4.5 0.094 12.2 3.1 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_S27e PF01667.12 OAJ05275.1 - 0.13 11.8 1.0 0.26 10.8 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 RNA_pol_3_Rpc31 PF11705.3 OAJ05276.1 - 0.016 15.1 6.0 0.027 14.4 4.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TT_ORF2 PF02957.10 OAJ05276.1 - 0.027 15.1 1.4 0.027 15.1 1.0 1.8 2 0 0 2 2 2 0 TT viral ORF2 Ribosom_S12_S23 PF00164.20 OAJ05276.1 - 0.034 13.5 1.0 0.064 12.6 0.7 1.5 1 1 0 1 1 1 0 Ribosomal protein S12/S23 Cwf_Cwc_15 PF04889.7 OAJ05276.1 - 0.28 10.8 9.8 0.086 12.5 5.0 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 OAJ05276.1 - 0.81 9.3 4.8 0.099 12.3 0.5 1.6 2 0 0 2 2 2 0 FAM176 family DUF3987 PF13148.1 OAJ05276.1 - 5.4 5.4 6.9 8.3 4.8 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) MULE PF10551.4 OAJ05277.1 - 3.8e-10 39.8 0.5 2.4e-09 37.2 0.3 2.2 1 1 0 1 1 1 1 MULE transposase domain Peptidase_C48 PF02902.14 OAJ05277.1 - 7.9e-07 28.9 0.0 2.3e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.12 OAJ05277.1 - 3.6e-05 23.1 0.4 7.2e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger PAS_9 PF13426.1 OAJ05278.1 - 1.9e-20 73.1 0.0 2.1e-19 69.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 OAJ05278.1 - 1.6e-07 31.1 0.0 3.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold RGS PF00615.14 OAJ05278.1 - 1.4e-06 28.4 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.5 OAJ05278.1 - 2.5e-05 24.2 0.0 0.00039 20.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 OAJ05278.1 - 0.02 14.7 0.0 0.46 10.4 0.0 2.8 2 0 0 2 2 2 0 PAS domain PAS_3 PF08447.6 OAJ05278.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold Ku PF02735.11 OAJ05279.1 - 1.5e-17 63.6 2.8 5.7e-17 61.7 0.0 3.1 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 OAJ05279.1 - 4.4e-12 45.9 0.0 1.1e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.23 OAJ05279.1 - 0.043 13.5 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Hexapep PF00132.19 OAJ05280.1 - 1.9e-07 30.3 15.2 0.019 14.4 0.5 4.0 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 OAJ05280.1 - 2.6e-06 26.8 8.7 0.001 18.5 1.2 3.4 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase WD40 PF00400.27 OAJ05281.1 - 8.4e-24 82.5 9.8 7.4e-08 31.9 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Mito_carr PF00153.22 OAJ05282.1 - 1.5e-65 216.9 2.8 1.5e-23 82.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MTHFR PF02219.12 OAJ05283.1 - 1.8e-95 319.3 0.1 2.3e-84 282.9 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase Ala_racemase_N PF01168.15 OAJ05283.1 - 3.5e-26 92.1 0.5 1.6e-24 86.6 0.3 2.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain ECH PF00378.15 OAJ05284.1 - 2.1e-18 66.3 0.1 2.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L7Ae PF01248.21 OAJ05285.1 - 6.2e-28 96.1 1.6 7.6e-28 95.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1353 PF07087.6 OAJ05285.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) Cytochrom_B561 PF03188.11 OAJ05286.1 - 4e-10 39.6 12.6 7.1e-10 38.8 8.7 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_3 PF06653.6 OAJ05286.1 - 0.41 10.3 5.1 2.1 8.0 3.5 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like PepSY_TM_2 PF13703.1 OAJ05286.1 - 1.3 9.2 21.4 2.7 8.2 1.8 3.6 1 1 3 4 4 4 0 PepSY-associated TM helix MIF4G PF02854.14 OAJ05287.1 - 2.4e-17 63.0 0.0 9.4e-17 61.1 0.0 1.9 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.12 OAJ05287.1 - 1.8e-10 40.4 0.0 4.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 MA3 domain Nop14 PF04147.7 OAJ05287.1 - 0.0022 16.0 24.2 0.0034 15.3 16.8 1.4 1 0 0 1 1 1 1 Nop14-like family RRN3 PF05327.6 OAJ05287.1 - 0.26 9.3 5.5 0.57 8.2 3.8 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleo_P87 PF07267.6 OAJ05287.1 - 10 4.6 9.3 19 3.7 6.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 COX5B PF01215.14 OAJ05288.1 - 4.4e-41 139.7 0.0 5.5e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.4 OAJ05288.1 - 0.028 14.2 0.3 0.043 13.6 0.2 1.3 1 0 0 1 1 1 0 Zinc-finger domain Cpn60_TCP1 PF00118.19 OAJ05289.1 - 1.1e-144 482.7 0.2 1.2e-144 482.5 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 OAJ05290.1 - 2.6e-22 77.8 4.4 7.6e-07 28.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat MMS1_N PF10433.4 OAJ05290.1 - 0.097 10.7 0.0 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.7 OAJ05290.1 - 0.18 11.4 2.1 0.27 10.9 0.1 2.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Spo12 PF05032.7 OAJ05291.1 - 6.7e-10 38.4 3.9 1.5e-09 37.2 2.7 1.7 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.2 OAJ05291.1 - 0.0014 18.9 0.0 0.0028 18.0 0.0 1.6 1 1 1 2 2 2 1 SnoaL-like domain ubiquitin PF00240.18 OAJ05292.1 - 2e-24 84.7 0.1 2.2e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ05292.1 - 1.6e-15 56.4 0.0 1.8e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ05292.1 - 0.0003 20.9 0.0 0.00038 20.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain Methyltransf_31 PF13847.1 OAJ05293.1 - 2.6e-13 49.8 0.0 3.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05293.1 - 2.6e-12 47.2 0.0 4.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ05293.1 - 7.4e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ05293.1 - 7.4e-07 29.2 0.0 1.8e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 OAJ05293.1 - 1e-05 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ05293.1 - 5.3e-05 23.5 0.0 0.00012 22.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ05293.1 - 6.6e-05 22.6 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ05293.1 - 0.00011 22.6 0.0 0.00039 20.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 OAJ05293.1 - 0.043 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Las1 PF04031.8 OAJ05294.1 - 1.1e-43 148.5 0.1 1.3e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Las1-like Chitin_synth_2 PF03142.10 OAJ05295.1 - 2.5e-282 936.9 0.0 3.1e-282 936.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 OAJ05295.1 - 3.9e-17 62.5 0.3 9.7e-17 61.3 0.2 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 OAJ05295.1 - 1.5e-15 57.6 0.0 3.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ05295.1 - 3.3e-05 23.2 0.1 0.00074 18.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ05295.1 - 0.0042 16.7 0.0 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 adh_short_C2 PF13561.1 OAJ05297.1 - 3.8e-30 105.4 0.1 4.5e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ05297.1 - 1.7e-18 67.1 0.6 2.5e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ05297.1 - 4.2e-08 33.0 0.1 6.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF930 PF06059.7 OAJ05297.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) Glyco_tran_WecB PF03808.8 OAJ05297.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Pkinase PF00069.20 OAJ05304.1 - 1.3e-32 113.0 0.0 2.8e-18 65.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05304.1 - 9.8e-15 54.3 0.0 3.3e-13 49.3 0.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ05304.1 - 0.33 10.2 0.0 0.56 9.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CMV_1a PF12467.3 OAJ05305.1 - 4.1 7.7 12.9 1 9.6 6.2 2.0 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family CAP PF00188.21 OAJ05306.1 - 4.7e-14 52.9 0.6 6.3e-14 52.5 0.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SE PF08491.5 OAJ05307.1 - 3.7e-80 268.7 0.0 4.7e-36 124.0 0.0 3.2 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.19 OAJ05307.1 - 1e-12 47.6 0.5 7.7e-09 34.9 0.2 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ05307.1 - 8.7e-10 38.1 0.3 5.8e-06 25.5 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 OAJ05307.1 - 1.9e-07 31.1 0.0 3.4e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ05307.1 - 3.8e-05 23.6 0.6 0.00014 21.8 0.5 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 OAJ05307.1 - 0.0002 20.3 0.4 0.00093 18.1 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.11 OAJ05307.1 - 0.00046 19.6 0.1 0.00092 18.6 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 OAJ05307.1 - 0.00052 18.9 1.0 0.0019 17.1 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 OAJ05307.1 - 0.00079 19.1 0.1 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 OAJ05307.1 - 0.0014 17.7 0.1 0.0033 16.5 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 OAJ05307.1 - 0.003 16.6 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 OAJ05307.1 - 0.0044 16.7 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 OAJ05307.1 - 0.0096 16.3 0.0 0.028 14.8 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 OAJ05307.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 OAJ05307.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 OAJ05307.1 - 0.026 13.4 1.0 0.067 12.1 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 OAJ05307.1 - 0.027 13.1 1.0 0.18 10.3 0.2 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Saccharop_dh PF03435.13 OAJ05307.1 - 0.038 12.9 0.2 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Cytochrom_B558a PF05038.8 OAJ05307.1 - 0.081 12.5 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit HI0933_like PF03486.9 OAJ05307.1 - 0.11 10.9 0.1 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 OAJ05307.1 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF1180 PF06679.7 OAJ05307.1 - 0.13 12.1 1.5 2.9 7.7 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) F420_oxidored PF03807.12 OAJ05307.1 - 0.14 12.6 0.1 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAJ05307.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1183 PF06682.7 OAJ05308.1 - 1.7e-50 172.4 32.0 8.1e-49 166.9 22.2 2.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) TPR_12 PF13424.1 OAJ05309.1 - 3.1e-42 142.3 55.5 5.9e-11 42.1 0.9 9.5 4 2 6 10 10 10 9 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ05309.1 - 1e-29 101.5 65.0 2e-05 24.3 0.4 13.2 13 0 0 13 13 13 9 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05309.1 - 8.5e-10 37.8 24.5 8 6.6 0.1 11.9 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ05309.1 - 1e-05 24.9 4.2 9.1 6.0 0.0 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ05309.1 - 0.00047 20.3 26.6 2.5 8.7 0.2 10.9 11 0 0 11 11 11 1 Tetratricopeptide repeat DUF666 PF05006.7 OAJ05309.1 - 0.035 14.1 0.0 40 4.1 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF666) TPR_11 PF13414.1 OAJ05309.1 - 0.04 13.5 41.7 0.15 11.7 1.0 7.6 2 1 9 11 11 11 0 TPR repeat DUF4645 PF15488.1 OAJ05309.1 - 0.056 12.6 0.9 10 5.1 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4645) TPR_8 PF13181.1 OAJ05309.1 - 0.18 11.6 15.8 25 4.9 0.0 8.6 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ05309.1 - 1.2 8.9 21.3 0.53 10.0 0.3 5.2 2 2 4 7 7 7 0 Domain of Unknown Function (DUF3856) Arrestin_N PF00339.24 OAJ05311.1 - 5.1e-05 23.1 1.6 0.00016 21.4 0.0 2.6 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain ATE_N PF04376.8 OAJ05312.1 - 0.014 15.1 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus DUF969 PF06149.7 OAJ05312.1 - 0.11 11.6 2.3 0.18 11.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF969) FGGY_N PF00370.16 OAJ05313.1 - 1.5e-73 247.1 0.1 2.1e-73 246.6 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 OAJ05313.1 - 3.1e-67 226.0 3.7 5.7e-67 225.1 1.5 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain ADH_zinc_N PF00107.21 OAJ05314.1 - 2.3e-36 124.2 0.4 4e-36 123.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ05314.1 - 2e-14 54.5 0.0 4.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ05314.1 - 6.2e-07 29.1 0.0 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 OAJ05314.1 - 0.022 14.2 0.2 0.035 13.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 OAJ05314.1 - 0.14 12.1 0.7 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding CBM_5_12 PF02839.9 OAJ05317.1 - 0.06 12.9 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain TPR_2 PF07719.12 OAJ05318.1 - 3.3e-31 104.6 14.3 8.6e-05 22.1 0.0 9.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05318.1 - 4.9e-23 80.5 16.6 8.8e-08 31.6 0.1 7.8 5 1 5 10 10 10 7 TPR repeat Apc3 PF12895.2 OAJ05318.1 - 2.1e-22 79.0 7.8 3.3e-09 36.7 0.6 5.5 6 0 0 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 OAJ05318.1 - 1.3e-21 75.2 8.0 0.0052 16.3 0.0 8.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05318.1 - 2.3e-19 69.5 28.2 1.9e-08 34.7 0.0 7.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ05318.1 - 1.1e-16 60.4 17.9 7.4e-07 29.0 0.1 8.4 5 1 3 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ05318.1 - 7.9e-14 50.9 25.4 0.0061 17.0 0.2 9.4 4 1 5 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ05318.1 - 1.8e-11 43.2 6.3 0.58 10.5 0.0 7.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05318.1 - 5.8e-11 41.3 0.0 0.95 9.3 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ05318.1 - 2e-10 40.8 17.3 0.017 15.4 0.3 7.5 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ05318.1 - 1e-08 34.8 7.9 0.049 13.5 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ05318.1 - 1.4e-07 31.4 14.6 3.6 8.2 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ05318.1 - 1.4e-07 30.7 7.4 0.34 10.7 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ05318.1 - 0.00025 20.8 9.6 0.51 10.2 0.0 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ05318.1 - 0.78 9.8 12.1 9.1 6.4 1.0 4.9 4 1 0 4 4 3 0 Tetratricopeptide repeat MBOAT_2 PF13813.1 OAJ05319.1 - 1.1e-08 34.9 3.9 4.3e-06 26.6 2.7 2.6 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L4 PF00573.17 OAJ05320.1 - 4.4e-60 202.3 0.0 6.4e-60 201.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.1 OAJ05320.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DUF3591 PF12157.3 OAJ05321.1 - 1.6e-170 567.4 0.2 2.1e-170 567.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 OAJ05321.1 - 2e-05 24.1 4.2 5.5e-05 22.7 2.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 OAJ05321.1 - 0.086 12.8 2.0 0.16 11.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M16_C PF05193.16 OAJ05324.1 - 1.4e-24 86.7 0.0 2e-15 56.9 0.0 3.2 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 OAJ05324.1 - 1.3e-07 31.5 0.1 8.8e-07 28.7 0.0 2.3 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF1949 PF09186.6 OAJ05324.1 - 0.061 12.9 0.0 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DUF3439 PF11921.3 OAJ05325.1 - 9.7 5.9 12.9 0.49 10.1 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4248 PF14053.1 OAJ05326.1 - 0.036 13.6 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) ABC_tran PF00005.22 OAJ05328.1 - 1.7e-46 157.8 0.0 1.1e-24 87.2 0.0 3.4 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 OAJ05328.1 - 9.7e-16 58.5 1.9 0.0058 16.6 0.1 4.3 2 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 OAJ05328.1 - 5.9e-10 38.7 0.2 0.042 13.0 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ05328.1 - 1.9e-08 34.8 0.0 0.0015 18.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ05328.1 - 8.7e-07 28.3 0.3 0.066 12.7 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 OAJ05328.1 - 2.1e-06 27.0 0.0 0.039 13.0 0.0 3.4 2 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.18 OAJ05328.1 - 4.4e-06 26.6 0.0 0.019 14.9 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase Chromo PF00385.19 OAJ05328.1 - 5.8e-06 25.8 0.1 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_2 PF13646.1 OAJ05328.1 - 7.3e-06 26.1 5.2 0.14 12.4 0.1 4.7 4 1 0 4 4 4 1 HEAT repeats Miro PF08477.8 OAJ05328.1 - 2.3e-05 24.8 0.2 0.076 13.5 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_22 PF13401.1 OAJ05328.1 - 6.5e-05 23.0 0.0 0.85 9.7 0.0 3.9 4 0 0 4 4 4 2 AAA domain HEAT_EZ PF13513.1 OAJ05328.1 - 8e-05 23.0 6.1 1.2 9.6 0.0 5.9 5 2 2 7 7 5 1 HEAT-like repeat AAA_16 PF13191.1 OAJ05328.1 - 0.00014 21.8 6.1 0.027 14.4 0.0 4.3 3 1 1 4 4 4 1 AAA ATPase domain AAA_10 PF12846.2 OAJ05328.1 - 0.00032 20.2 2.1 0.79 9.1 0.0 4.1 4 1 0 4 4 4 1 AAA-like domain NACHT PF05729.7 OAJ05328.1 - 0.00043 19.9 0.1 1.7 8.2 0.0 3.3 3 0 0 3 3 3 2 NACHT domain ArgK PF03308.11 OAJ05328.1 - 0.00067 18.5 0.3 0.11 11.2 0.0 2.6 2 0 0 2 2 2 1 ArgK protein DUF258 PF03193.11 OAJ05328.1 - 0.0009 18.4 0.1 0.044 12.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 OAJ05328.1 - 0.0016 18.3 0.0 0.85 9.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 OAJ05328.1 - 0.0031 17.2 0.8 0.85 9.3 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAJ05328.1 - 0.0033 17.3 0.0 0.74 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ05328.1 - 0.0036 16.7 0.1 4.8 6.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.1 OAJ05328.1 - 0.004 17.9 0.0 0.69 10.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 OAJ05328.1 - 0.0046 16.5 0.3 1.3 8.5 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_28 PF13521.1 OAJ05328.1 - 0.0084 16.0 0.0 4.5 7.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain CLASP_N PF12348.3 OAJ05328.1 - 0.0088 15.4 0.1 1.3 8.3 0.1 2.6 1 1 1 2 2 2 1 CLASP N terminal Zeta_toxin PF06414.7 OAJ05328.1 - 0.0095 15.0 0.3 7.3 5.6 0.1 3.2 3 0 0 3 3 3 0 Zeta toxin DUF87 PF01935.12 OAJ05328.1 - 0.023 14.5 0.7 7.8 6.2 0.0 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 GTP_EFTU PF00009.22 OAJ05328.1 - 0.032 13.6 0.2 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 OAJ05328.1 - 0.053 13.3 0.1 0.95 9.2 0.0 2.5 2 0 0 2 2 2 0 Dynamin family HEAT PF02985.17 OAJ05328.1 - 0.066 13.3 5.4 60 4.1 0.0 5.7 6 0 0 6 6 5 0 HEAT repeat RNA_helicase PF00910.17 OAJ05328.1 - 0.081 13.1 0.0 4.5 7.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 OAJ05328.1 - 0.094 12.1 0.2 5.8 6.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 OAJ05328.1 - 0.095 11.6 0.1 11 4.8 0.0 2.7 3 0 0 3 3 2 0 KAP family P-loop domain MFS_1 PF07690.11 OAJ05329.1 - 2.5e-34 118.5 27.9 2.5e-34 118.5 19.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyltransferase PF01553.16 OAJ05330.1 - 8.6e-23 80.2 0.0 1.4e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Brix PF04427.13 OAJ05331.1 - 2.8e-48 164.1 0.0 3.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain Aminotran_3 PF00202.16 OAJ05332.1 - 7e-34 117.1 0.0 4.1e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.1 OAJ05332.1 - 1.7e-24 86.5 0.0 4.1e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Pep_M12B_propep PF01562.14 OAJ05332.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide Serglycin PF04360.7 OAJ05333.1 - 0.2 11.4 1.6 0.32 10.7 1.1 1.4 1 0 0 1 1 1 0 Serglycin BRO1 PF03097.13 OAJ05334.1 - 2.5e-94 316.1 0.2 2.5e-94 316.1 0.1 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ05334.1 - 1.1e-60 205.0 12.9 3.9e-60 203.3 8.9 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Ribosomal_S10 PF00338.17 OAJ05335.1 - 8.4e-32 108.8 0.2 1e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Cupin_8 PF13621.1 OAJ05336.1 - 7e-45 153.4 0.0 5.5e-24 85.0 0.0 3.9 2 2 0 3 3 3 2 Cupin-like domain Acyl-thio_N PF12590.3 OAJ05336.1 - 0.022 15.2 0.4 0.16 12.4 0.0 2.8 2 1 1 3 3 3 0 Acyl-ATP thioesterase Gcd10p PF04189.8 OAJ05338.1 - 1.7e-68 230.9 0.0 3e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family Tir_receptor_C PF07489.6 OAJ05338.1 - 0.0034 17.1 0.2 0.0082 15.9 0.1 1.6 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus RNase_H2_suC PF08615.6 OAJ05338.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Dicty_REP PF05086.7 OAJ05339.1 - 2.3 5.8 6.7 3.2 5.3 4.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SUI1 PF01253.17 OAJ05340.1 - 4.4e-12 45.6 0.0 9.1e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pol_alpha_B_N PF08418.5 OAJ05340.1 - 0.011 15.3 1.3 0.015 14.8 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SPATIAL PF15256.1 OAJ05340.1 - 0.066 13.2 0.5 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 SPATIAL GA PF01468.12 OAJ05340.1 - 0.25 11.5 5.9 0.12 12.5 1.5 2.2 2 0 0 2 2 2 0 GA module NARP1 PF12569.3 OAJ05340.1 - 0.38 9.4 4.0 0.54 8.9 2.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Kinesin PF00225.18 OAJ05341.1 - 1.4e-105 352.7 0.0 3.3e-105 351.4 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain FLILHELTA PF10306.4 OAJ05342.1 - 3.9e-13 49.2 0.0 7.8e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 OAJ05342.1 - 0.0072 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribonuclease_P PF00825.13 OAJ05343.1 - 0.00086 19.1 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease P Coa1 PF08695.5 OAJ05344.1 - 1.3e-32 111.7 0.0 2e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF3459 PF11941.3 OAJ05344.1 - 0.17 12.0 0.2 0.17 12.0 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3459) RICTOR_M PF14666.1 OAJ05345.1 - 6.3e-69 231.4 0.2 1.9e-67 226.5 0.1 3.1 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 OAJ05345.1 - 2e-53 181.3 0.0 7.2e-42 143.2 0.0 3.9 4 1 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 OAJ05345.1 - 2.5e-26 91.8 0.1 1.3e-25 89.6 0.0 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 OAJ05345.1 - 1.7e-25 88.7 0.4 6.5e-24 83.6 0.0 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 OAJ05345.1 - 2.3e-07 30.4 0.9 5.2e-07 29.3 0.6 1.7 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.4 OAJ05345.1 - 0.026 12.8 0.1 3.8 5.6 0.0 2.8 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 OAJ05345.1 - 0.22 11.6 1.3 2.8 8.2 0.2 3.5 4 0 0 4 4 4 0 HEAT repeat IBR PF01485.16 OAJ05346.1 - 1.3e-07 31.4 26.6 0.00024 20.9 3.3 3.5 3 0 0 3 3 3 3 IBR domain FAM176 PF14851.1 OAJ05346.1 - 0.098 12.3 1.5 0.5 10.0 1.1 2.2 1 0 0 1 1 1 0 FAM176 family COX5A PF02284.11 OAJ05347.1 - 9.3e-42 141.3 0.4 1.1e-41 141.0 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Mt_ATP-synt_B PF05405.9 OAJ05348.1 - 3.9e-47 159.7 5.7 4.8e-47 159.4 4.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.3 OAJ05348.1 - 0.00037 20.2 0.2 0.00063 19.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Cauli_DNA-bind PF03310.8 OAJ05348.1 - 0.16 11.8 1.4 0.25 11.1 0.3 1.7 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein MFS_1 PF07690.11 OAJ05350.1 - 1.5e-17 63.3 41.5 3.3e-17 62.2 28.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M57 PF12388.3 OAJ05350.1 - 0.25 10.6 0.3 0.55 9.5 0.1 1.6 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Kinesin PF00225.18 OAJ05354.1 - 1.9e-110 368.7 2.1 2e-110 368.6 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Apolipoprotein PF01442.13 OAJ05354.1 - 0.0012 18.3 21.9 0.0012 18.3 15.2 4.2 3 2 1 4 4 4 1 Apolipoprotein A1/A4/E domain Sox_N PF12444.3 OAJ05354.1 - 2.1 9.5 0.0 2.1 9.5 0.0 4.1 3 1 0 3 3 3 0 Sox developmental protein N terminal Reo_sigmaC PF04582.7 OAJ05354.1 - 9.5 5.2 31.6 0.23 10.5 1.9 4.1 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Ribosomal_S21e PF01249.13 OAJ05355.1 - 2.3e-34 117.1 0.0 2.6e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e SpoA PF01052.15 OAJ05355.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Pirin PF02678.11 OAJ05356.1 - 3.6e-29 100.7 0.5 7e-29 99.8 0.3 1.5 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 OAJ05356.1 - 5.3e-08 32.2 5.8 8e-08 31.6 0.1 3.1 3 0 0 3 3 3 1 Cupin domain Dmrt1 PF12374.3 OAJ05356.1 - 5.1 7.5 7.1 12 6.3 1.2 2.7 2 1 0 3 3 3 0 Double-sex mab3 related transcription factor 1 Tubulin PF00091.20 OAJ05357.1 - 6.6e-72 241.8 0.0 1.2e-71 241.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ05357.1 - 4.3e-49 165.7 0.5 6.7e-49 165.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ05357.1 - 6.9e-07 29.3 0.0 1.9e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ05357.1 - 0.00041 19.8 0.0 0.00092 18.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Lactonase PF10282.4 OAJ05357.1 - 0.11 11.5 0.0 1.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ABC2_membrane PF01061.19 OAJ05358.1 - 5.1e-71 238.1 55.6 7e-41 139.6 12.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ05358.1 - 1.9e-35 122.1 0.0 7.3e-18 65.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 OAJ05358.1 - 2.7e-32 110.4 0.2 6.4e-29 99.6 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 OAJ05358.1 - 1.3e-11 44.4 0.0 3.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAJ05358.1 - 3.7e-06 26.4 0.1 0.00099 18.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAJ05358.1 - 8.6e-06 25.8 0.5 0.00053 20.0 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 OAJ05358.1 - 1.8e-05 24.0 0.0 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 OAJ05358.1 - 3.3e-05 23.5 0.7 0.018 14.6 0.1 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 OAJ05358.1 - 0.00016 21.8 0.3 0.056 13.5 0.1 3.5 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ05358.1 - 0.00022 20.7 0.1 0.13 11.7 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family cobW PF02492.14 OAJ05358.1 - 0.0058 16.1 1.3 0.028 13.8 0.3 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 OAJ05358.1 - 0.0097 15.5 0.0 0.093 12.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 OAJ05358.1 - 0.025 14.8 0.0 0.18 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 OAJ05358.1 - 0.03 13.8 0.4 0.16 11.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 OAJ05358.1 - 0.034 14.9 0.0 0.21 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ05358.1 - 0.035 14.0 0.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 OAJ05358.1 - 0.045 14.2 0.0 0.7 10.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 OAJ05358.1 - 0.058 13.2 0.2 0.36 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 OAJ05358.1 - 0.12 11.9 0.4 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 OAJ05358.1 - 0.16 11.9 0.0 6.1 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 OAJ05358.1 - 0.19 11.6 0.0 0.19 11.6 0.0 2.3 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 OAJ05358.1 - 0.28 10.6 0.4 0.86 9.0 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Topoisom_bac PF01131.15 OAJ05359.1 - 1.1e-87 294.5 0.0 1.3e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 OAJ05359.1 - 2e-20 72.6 0.0 3.7e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CCHC PF00098.18 OAJ05359.1 - 2e-05 24.2 3.2 2e-05 24.2 2.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ05359.1 - 0.11 12.2 2.0 0.17 11.6 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ05359.1 - 0.16 11.6 0.8 0.56 9.9 0.6 2.0 1 0 0 1 1 1 0 Zinc knuckle TTL PF03133.10 OAJ05360.1 - 1.5e-43 148.7 0.0 1.9e-30 105.8 0.0 2.1 1 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 OAJ05360.1 - 0.014 15.1 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain Nro1 PF12753.2 OAJ05360.1 - 0.052 12.4 3.3 0.079 11.9 2.3 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Nucleoplasmin PF03066.10 OAJ05360.1 - 1.5 8.2 7.0 3.1 7.2 4.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 OAJ05360.1 - 2 6.3 4.7 3.1 5.7 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 OAJ05360.1 - 5.4 5.6 10.1 9.7 4.7 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 OAJ05360.1 - 6 7.2 9.2 0.97 9.7 3.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HSA PF07529.8 OAJ05361.1 - 3e-15 55.7 3.7 3e-15 55.7 2.5 4.1 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 OAJ05361.1 - 1.2e-08 34.9 0.0 2.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 OAJ05361.1 - 0.00057 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SRP54 PF00448.17 OAJ05362.1 - 3.8e-75 251.6 0.2 3.8e-75 251.6 0.1 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 OAJ05362.1 - 1.9e-21 76.2 0.0 1.9e-21 76.2 0.0 4.4 3 2 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.14 OAJ05362.1 - 1.1e-11 44.6 1.3 2.5e-11 43.5 0.9 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 OAJ05362.1 - 2.2e-05 23.9 0.5 0.00012 21.5 0.3 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 OAJ05362.1 - 3.1e-05 23.8 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 OAJ05362.1 - 0.0026 17.7 0.1 1.4 8.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain MobB PF03205.9 OAJ05362.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 OAJ05362.1 - 0.0035 16.7 0.1 0.01 15.2 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Lipase_chap PF03280.9 OAJ05362.1 - 0.0061 16.0 0.8 1.4 8.3 0.1 2.5 2 0 0 2 2 2 2 Proteobacterial lipase chaperone protein AAA_22 PF13401.1 OAJ05362.1 - 0.0073 16.4 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 OAJ05362.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 OAJ05362.1 - 0.024 15.4 0.0 0.057 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 OAJ05362.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Lysine_decarbox PF03641.9 OAJ05363.1 - 2e-33 115.0 0.0 2.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase FAD_binding_7 PF03441.9 OAJ05364.1 - 7.9e-63 212.2 0.1 1.1e-62 211.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ05364.1 - 8e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase ubiquitin PF00240.18 OAJ05365.1 - 2e-34 116.7 1.1 2.7e-34 116.3 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 OAJ05365.1 - 8.8e-20 70.1 0.8 1.3e-19 69.6 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.11 OAJ05365.1 - 3e-09 36.5 7.5 5.5e-09 35.7 5.2 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.1 OAJ05365.1 - 1.2e-05 25.4 0.2 4.1e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ05365.1 - 0.00027 20.6 0.0 0.00027 20.6 0.0 1.5 2 0 0 2 2 2 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ05365.1 - 0.0044 16.8 0.3 0.018 14.9 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 OAJ05365.1 - 0.01 16.0 0.1 0.011 15.8 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain HMG-CoA_red PF00368.13 OAJ05366.1 - 1e-157 524.5 7.5 1.4e-157 524.1 5.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 OAJ05366.1 - 3.2e-20 72.1 1.1 1.9e-09 37.1 0.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 OAJ05366.1 - 6.4e-07 27.7 3.1 0.0025 15.8 0.0 2.2 2 0 0 2 2 2 2 Patched family Prefoldin PF02996.12 OAJ05367.1 - 2e-26 92.0 0.0 2.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 OAJ05367.1 - 0.0047 16.1 0.7 0.47 9.6 0.3 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 OAJ05367.1 - 0.0069 16.1 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Cep57_MT_bd PF06657.8 OAJ05367.1 - 0.095 12.6 0.2 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Apolipoprotein PF01442.13 OAJ05367.1 - 0.11 12.0 1.1 8.2 5.8 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Pet191_N PF10203.4 OAJ05368.1 - 1.2e-23 82.9 2.3 1.4e-23 82.6 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF3551 PF12071.3 OAJ05368.1 - 0.28 10.7 1.7 0.47 10.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) GMC_oxred_N PF00732.14 OAJ05369.1 - 2.9e-38 131.6 0.0 4.9e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ05369.1 - 3.2e-20 72.8 0.2 1.7e-19 70.5 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 OAJ05369.1 - 3.6e-09 35.9 1.0 1.2e-05 24.3 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ05369.1 - 1.3e-05 24.2 0.7 0.00017 20.5 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 OAJ05369.1 - 6e-05 22.2 0.3 9.9e-05 21.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 OAJ05369.1 - 6.1e-05 22.9 0.2 0.00016 21.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ05369.1 - 0.00024 21.0 0.3 0.0014 18.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ05369.1 - 0.0061 15.6 0.3 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 OAJ05369.1 - 0.011 14.6 0.1 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 OAJ05369.1 - 0.018 13.4 0.3 0.03 12.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 OAJ05369.1 - 0.047 12.7 1.2 0.072 12.1 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 OAJ05369.1 - 0.11 11.9 0.4 0.22 10.9 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 OAJ05369.1 - 0.15 10.8 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ABC_tran PF00005.22 OAJ05370.1 - 2.7e-15 56.8 0.0 9.1e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ05370.1 - 3.8e-09 36.9 0.2 0.00038 20.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 OAJ05370.1 - 1.1e-05 24.7 0.0 0.024 13.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 OAJ05370.1 - 0.00074 18.9 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 OAJ05370.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ05370.1 - 0.032 13.6 0.2 0.15 11.4 0.0 2.0 2 1 0 3 3 3 0 AAA-like domain AAA_28 PF13521.1 OAJ05370.1 - 0.08 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 OAJ05370.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 OAJ05370.1 - 0.13 11.4 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 OAJ05370.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ05370.1 - 0.16 11.9 0.0 0.5 10.3 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase Arf PF00025.16 OAJ05370.1 - 0.26 10.5 0.1 0.53 9.5 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Fcf1 PF04900.7 OAJ05371.1 - 8.4e-39 131.7 0.5 1.3e-38 131.1 0.4 1.3 1 0 0 1 1 1 1 Fcf1 CLN3 PF02487.12 OAJ05372.1 - 2.1e-62 211.2 12.3 1.2e-26 93.4 0.0 4.0 3 1 1 4 4 4 4 CLN3 protein Glyco_transf_22 PF03901.12 OAJ05374.1 - 3.3e-26 92.2 1.9 1.7e-18 66.8 0.4 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Tannase PF07519.6 OAJ05375.1 - 3.7e-75 253.4 0.2 5e-66 223.3 0.0 2.2 2 0 0 2 2 2 2 Tannase and feruloyl esterase UreD PF01774.12 OAJ05376.1 - 5.7e-51 172.9 0.0 2.7e-50 170.7 0.0 2.0 1 1 0 1 1 1 1 UreD urease accessory protein NSP2-B_epitope PF14757.1 OAJ05376.1 - 0.58 9.5 6.5 0.28 10.6 0.1 2.3 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Abhydrolase_4 PF08386.5 OAJ05377.1 - 2.6e-13 49.7 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ05377.1 - 1.3e-12 47.8 0.0 8.3e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ05377.1 - 7.3e-07 29.2 0.2 6.9e-06 26.1 0.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ05377.1 - 0.083 12.6 0.0 0.93 9.2 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 OAJ05378.1 - 5.1e-22 78.5 0.0 6.6e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ05378.1 - 7.8e-08 32.1 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ05378.1 - 3.1e-07 30.4 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 OAJ05378.1 - 0.00045 20.3 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAJ05378.1 - 0.00083 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 OAJ05378.1 - 0.004 16.1 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 OAJ05378.1 - 0.0045 16.4 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 OAJ05378.1 - 0.036 13.8 0.0 0.085 12.5 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4450 PF14614.1 OAJ05378.1 - 0.047 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) ApbA PF02558.11 OAJ05378.1 - 0.048 13.0 0.1 0.12 11.8 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.27 OAJ05379.1 - 5.3e-15 54.6 1.2 8.2e-09 35.0 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat BRCT PF00533.21 OAJ05380.1 - 4.7e-06 26.6 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 OAJ05380.1 - 0.00018 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.2 OAJ05380.1 - 0.00024 20.9 0.0 0.00064 19.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 OAJ05380.1 - 0.00089 19.3 0.1 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain NPR1_like_C PF12313.3 OAJ05380.1 - 0.043 13.2 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Sec23_trunk PF04811.10 OAJ05381.1 - 1.9e-57 194.4 0.0 6.7e-51 172.9 0.0 2.1 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ05381.1 - 9.1e-22 76.4 0.1 1.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 OAJ05381.1 - 1e-19 70.7 0.0 2.7e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 OAJ05381.1 - 4.9e-16 58.0 5.5 9.4e-16 57.0 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 OAJ05381.1 - 3.3e-05 23.4 0.2 0.00015 21.4 0.0 2.3 3 0 0 3 3 3 1 Gelsolin repeat LSM PF01423.17 OAJ05382.1 - 1.4e-11 43.7 0.1 1.7e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SlyX PF04102.7 OAJ05383.1 - 0.00039 20.7 2.1 0.00039 20.7 1.4 4.4 3 1 1 4 4 4 1 SlyX TPR_MLP1_2 PF07926.7 OAJ05383.1 - 0.0023 17.7 19.7 0.0023 17.7 13.7 3.4 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 OAJ05383.1 - 0.042 13.0 8.6 0.068 12.3 0.3 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF869 PF05911.6 OAJ05383.1 - 0.42 8.7 34.1 0.074 11.2 11.3 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 OAJ05383.1 - 3.4 7.5 45.3 0.037 13.9 9.1 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding CPSase_L_D2 PF02786.12 OAJ05384.1 - 9.6e-116 384.4 0.1 1.2e-83 279.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace_N PF02729.16 OAJ05384.1 - 8.5e-45 151.9 0.0 1.6e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_sm_chain PF00988.17 OAJ05384.1 - 1.7e-44 150.5 0.0 3.7e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_chain PF00289.17 OAJ05384.1 - 2.7e-41 140.1 0.0 2.7e-21 75.7 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain GATase PF00117.23 OAJ05384.1 - 4.2e-41 140.5 0.0 1.2e-40 138.9 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 OAJ05384.1 - 4.2e-40 136.3 0.0 9e-40 135.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 OAJ05384.1 - 2.1e-37 128.4 0.0 4.5e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 OAJ05384.1 - 7.4e-35 120.3 0.1 9.3e-20 71.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 OAJ05384.1 - 1.5e-21 76.4 0.1 1.1e-11 44.1 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 OAJ05384.1 - 5.6e-16 58.3 0.0 3.8e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 OAJ05384.1 - 6.9e-16 58.2 0.1 4.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 OAJ05384.1 - 1.1e-11 44.5 0.0 4.6e-11 42.5 0.0 2.2 1 0 0 1 1 1 1 MGS-like domain ATP-grasp_3 PF02655.9 OAJ05384.1 - 1.2e-05 25.2 0.1 0.072 12.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 OAJ05384.1 - 1.5e-05 24.5 0.0 0.00028 20.3 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 OAJ05384.1 - 0.005 16.3 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 OAJ05384.1 - 0.011 15.2 0.0 0.25 10.8 0.0 2.7 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Cu-oxidase_3 PF07732.10 OAJ05385.1 - 3.5e-32 110.6 8.5 4.9e-31 106.9 0.1 3.7 3 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 OAJ05385.1 - 5.9e-18 65.2 0.0 1.6e-14 54.1 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ05385.1 - 2.6e-15 56.1 10.7 3.8e-12 45.8 3.7 3.4 2 2 0 2 2 2 2 Multicopper oxidase DPBB_1 PF03330.13 OAJ05386.1 - 2.2e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ05386.1 - 0.0017 18.0 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 Barwin family EthD PF07110.6 OAJ05386.1 - 0.14 13.1 0.3 0.14 13.1 0.2 2.1 2 0 0 2 2 2 0 EthD domain Raftlin PF15250.1 OAJ05386.1 - 2.5 6.5 7.6 0.37 9.2 2.2 1.8 2 0 0 2 2 2 0 Raftlin Glyoxalase_3 PF13468.1 OAJ05387.1 - 2.5e-22 79.6 1.3 8.7e-15 55.0 0.2 3.2 2 1 0 2 2 2 2 Glyoxalase-like domain DNA_ligase_A_M PF01068.16 OAJ05388.1 - 1.8e-56 190.7 0.1 3.9e-56 189.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 OAJ05388.1 - 6.3e-54 182.4 0.0 1.2e-53 181.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 OAJ05388.1 - 3.1e-25 88.3 0.2 2.2e-24 85.7 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 OAJ05388.1 - 0.0052 16.4 0.3 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain SMC_N PF02463.14 OAJ05389.1 - 7.7e-69 231.2 3.8 1e-66 224.3 2.7 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ05389.1 - 1e-19 70.6 3.2 1.5e-19 70.1 0.2 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 OAJ05389.1 - 1.3e-16 61.5 14.3 1.3e-16 61.5 9.9 6.5 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.1 OAJ05389.1 - 5.9e-14 52.7 10.5 1.3e-06 28.6 0.2 3.5 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 OAJ05389.1 - 2e-05 24.0 0.1 6.6e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 OAJ05389.1 - 6e-05 21.6 49.0 6e-05 21.6 34.0 4.1 3 1 0 4 4 3 1 Weak chloroplast movement under blue light XhlA PF10779.4 OAJ05389.1 - 0.00031 20.5 5.6 0.00031 20.5 3.9 7.9 7 3 0 9 9 9 2 Haemolysin XhlA ATG16 PF08614.6 OAJ05389.1 - 0.00058 19.7 15.0 0.00058 19.7 10.4 6.6 3 2 2 6 6 6 1 Autophagy protein 16 (ATG16) FliJ PF02050.11 OAJ05389.1 - 0.0015 18.5 12.4 0.0015 18.5 8.6 8.7 4 2 4 9 9 9 1 Flagellar FliJ protein Uds1 PF15456.1 OAJ05389.1 - 0.0023 17.9 12.7 0.0023 17.9 8.8 6.9 5 1 2 7 7 5 2 Up-regulated During Septation Reo_sigmaC PF04582.7 OAJ05389.1 - 0.15 11.2 28.8 0.2 10.7 0.9 5.4 3 1 2 6 6 6 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ05389.1 - 0.34 11.2 0.0 0.34 11.2 0.0 6.5 3 2 0 3 3 3 0 ABC transporter Longin PF13774.1 OAJ05390.1 - 3.3e-24 84.2 0.0 5.8e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 OAJ05390.1 - 4.5e-14 51.8 0.1 9.9e-14 50.7 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 OAJ05390.1 - 0.041 13.6 0.2 0.066 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FliJ PF02050.11 OAJ05390.1 - 0.079 13.0 0.3 0.079 13.0 0.2 1.7 2 1 1 3 3 3 0 Flagellar FliJ protein AAA_2 PF07724.9 OAJ05391.1 - 4.3e-31 108.1 0.0 1.8e-23 83.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 OAJ05391.1 - 2.4e-12 47.1 0.0 6.4e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 OAJ05391.1 - 1.5e-11 44.0 0.0 3.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 OAJ05391.1 - 1.7e-05 24.9 0.1 5.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ05391.1 - 4.7e-05 23.5 0.2 0.0003 20.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ05391.1 - 0.00058 19.5 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAJ05391.1 - 0.00067 20.4 0.0 0.0022 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ05391.1 - 0.0031 17.4 0.6 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 OAJ05391.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ05391.1 - 0.0085 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 OAJ05391.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.18 OAJ05391.1 - 0.011 14.5 0.2 0.035 12.8 0.0 1.8 2 0 0 2 2 2 0 MCM2/3/5 family NACHT PF05729.7 OAJ05391.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 OAJ05391.1 - 0.019 14.1 0.1 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 OAJ05391.1 - 0.019 15.2 0.0 0.059 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ05391.1 - 0.023 14.5 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 OAJ05391.1 - 0.062 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 OAJ05391.1 - 0.063 13.5 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 OAJ05391.1 - 0.069 12.7 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Pox_A32 PF04665.7 OAJ05391.1 - 0.24 10.6 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein TIG PF01833.19 OAJ05392.1 - 6.6e-13 48.4 1.4 5.3e-12 45.5 1.5 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank PF00023.25 OAJ05392.1 - 1.9e-12 46.2 1.3 8.6e-06 25.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 OAJ05392.1 - 1.4e-11 44.5 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ05392.1 - 9.6e-11 41.9 1.2 2.3e-10 40.6 0.9 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ05392.1 - 9.8e-11 41.5 0.6 9.2e-10 38.4 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ05392.1 - 1.3e-06 28.0 0.4 0.003 17.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Sybindin PF04099.7 OAJ05393.1 - 5.7e-40 136.3 0.0 6.3e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 OAJ05393.1 - 4.4e-08 33.0 0.0 4.4e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region YqeY PF09424.5 OAJ05394.1 - 3.1e-25 88.6 1.2 3.9e-25 88.3 0.8 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF3365 PF11845.3 OAJ05394.1 - 0.0077 16.0 1.2 0.0099 15.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) G6PD_N PF00479.17 OAJ05394.1 - 0.014 15.6 0.7 0.019 15.2 0.5 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3323 PF11796.3 OAJ05394.1 - 0.027 13.7 0.9 0.039 13.2 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) OmdA PF13376.1 OAJ05394.1 - 0.046 13.3 0.3 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF3776 PF12618.3 OAJ05394.1 - 0.3 11.6 3.3 0.12 12.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3776) TarH PF02203.10 OAJ05394.1 - 6.4 6.5 12.4 12 5.7 5.3 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue CFEM PF05730.6 OAJ05395.1 - 1.7e-08 34.1 9.4 3.3e-08 33.2 6.5 1.5 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 OAJ05395.1 - 0.6 10.2 5.1 1 9.5 3.6 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Hydrolase_6 PF13344.1 OAJ05396.1 - 3.9e-30 103.7 0.0 8.4e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ05396.1 - 1.8e-16 59.5 0.1 3.6e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 OAJ05396.1 - 2e-11 44.7 0.0 4.8e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 OAJ05396.1 - 0.00043 20.5 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 OAJ05396.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 OAJ05396.1 - 0.11 11.8 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DUF2346 PF09803.4 OAJ05397.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) CFEM PF05730.6 OAJ05398.1 - 0.001 18.8 4.7 0.001 18.8 3.3 2.1 2 0 0 2 2 2 1 CFEM domain CFEM PF05730.6 OAJ05399.1 - 1.3e-06 28.1 16.1 3.2e-06 26.8 11.1 1.7 1 1 0 1 1 1 1 CFEM domain TIL PF01826.12 OAJ05399.1 - 2.9 8.0 12.5 0.63 10.1 6.5 1.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain ATP-synt_D PF01813.12 OAJ05400.1 - 2.5e-66 222.9 4.5 3.6e-66 222.4 3.1 1.2 1 0 0 1 1 1 1 ATP synthase subunit D ATP-synt_B PF00430.13 OAJ05400.1 - 0.26 11.0 0.1 0.26 11.0 0.1 2.8 3 0 0 3 3 3 0 ATP synthase B/B' CF(0) Sigma70_ner PF04546.8 OAJ05400.1 - 1.1 8.7 15.8 1.1 8.8 6.7 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region WD40 PF00400.27 OAJ05401.1 - 7.3e-14 51.0 9.9 4e-05 23.3 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat GATA PF00320.22 OAJ05402.1 - 7.5e-27 92.3 21.1 4.6e-14 51.4 3.2 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 OAJ05402.1 - 2.2e-09 36.6 0.3 4.5e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 OAJ05402.1 - 0.001 18.3 6.3 0.06 12.6 0.9 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 OAJ05402.1 - 0.071 12.9 7.8 0.73 9.7 0.1 2.9 2 1 1 3 3 3 0 Double zinc ribbon NMD3 PF04981.8 OAJ05402.1 - 0.3 10.1 3.4 2.1 7.4 0.1 2.2 2 0 0 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.12 OAJ05402.1 - 0.95 9.1 7.3 1.4 8.6 0.6 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 OAJ05402.1 - 4.9 6.7 7.5 0.4 10.2 0.3 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 CFEM PF05730.6 OAJ05403.1 - 2.1e-08 33.8 13.2 3.8e-08 33.0 9.1 1.4 1 0 0 1 1 1 1 CFEM domain VSG_B PF13206.1 OAJ05403.1 - 0.19 10.8 6.6 0.27 10.3 4.6 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain GEMIN8 PF15348.1 OAJ05404.1 - 0.057 13.4 0.7 0.13 12.2 0.5 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Glyco_hydro_67N PF03648.9 OAJ05404.1 - 0.15 12.0 0.8 14 5.7 0.6 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Pkinase PF00069.20 OAJ05413.1 - 7.2e-51 172.8 0.0 1e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05413.1 - 1.1e-44 152.4 0.0 1.5e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ05413.1 - 0.0014 18.4 0.1 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family C1_1 PF00130.17 OAJ05413.1 - 0.0023 17.5 6.6 0.0048 16.5 4.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 OAJ05413.1 - 0.018 14.1 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H_2 PF13832.1 OAJ05413.1 - 0.17 11.8 3.9 0.36 10.8 2.7 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain Pox_ser-thr_kin PF05445.6 OAJ05413.1 - 0.4 9.4 0.0 0.58 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pol_alpha_B_N PF08418.5 OAJ05413.1 - 0.41 10.1 7.2 0.86 9.0 5.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-HC5HC2H PF13771.1 OAJ05413.1 - 0.56 10.3 3.6 1.2 9.3 2.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 OAJ05413.1 - 0.94 9.2 7.2 1.8 8.3 5.0 1.4 1 0 0 1 1 1 0 PHD-finger Kelch_4 PF13418.1 OAJ05414.1 - 4e-18 64.9 6.0 1.3e-07 31.2 0.1 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 OAJ05414.1 - 1.3e-12 47.3 2.8 0.00014 21.8 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.1 OAJ05414.1 - 7.6e-12 45.0 21.6 0.0003 20.8 0.3 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 OAJ05414.1 - 5.9e-09 35.6 3.6 0.0022 17.9 0.1 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 OAJ05414.1 - 0.00033 20.1 0.0 5.6 6.6 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 OAJ05414.1 - 0.0042 16.8 0.1 1.7 8.5 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Trypan_PARP PF05887.6 OAJ05415.1 - 0.3 10.8 5.5 0.41 10.4 3.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDE_3 PF13358.1 OAJ05416.1 - 1e-30 106.4 0.0 3e-30 104.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ05416.1 - 5.7e-11 42.5 0.5 1.3e-10 41.4 0.3 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ05416.1 - 1.3e-07 32.2 2.1 1.9e-07 31.7 0.2 2.2 2 1 0 2 2 2 1 Homeodomain-like domain DDE_1 PF03184.14 OAJ05416.1 - 2.8e-06 26.6 0.0 5.5e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 OAJ05416.1 - 3.2e-06 27.2 0.0 2.4e-05 24.4 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain HTH_33 PF13592.1 OAJ05416.1 - 0.00018 21.0 0.0 0.00047 19.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ05416.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 1.8 2 0 0 2 2 1 1 Transposase HTH_23 PF13384.1 OAJ05416.1 - 0.005 16.4 0.5 3.9 7.2 0.0 2.9 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 OAJ05416.1 - 0.0055 16.3 0.1 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_7 PF02796.10 OAJ05416.1 - 0.011 15.5 0.3 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DDE_Tnp_ISAZ013 PF07592.6 OAJ05416.1 - 0.013 14.2 0.0 0.19 10.4 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain DDE_Tnp_IS66 PF03050.9 OAJ05416.1 - 0.016 14.4 0.3 0.061 12.5 0.2 1.9 1 1 0 1 1 1 0 Transposase IS66 family HTH_28 PF13518.1 OAJ05416.1 - 0.068 13.1 0.6 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.15 OAJ05416.1 - 0.1 12.5 1.5 0.43 10.5 0.1 2.5 3 0 0 3 3 3 0 Transposase AAA_30 PF13604.1 OAJ05416.1 - 0.85 9.1 4.1 3 7.3 0.0 2.9 2 1 1 3 3 3 0 AAA domain Pox_Ag35 PF03286.9 OAJ05417.1 - 1.8 8.0 7.5 13 5.2 0.1 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein RVT_1 PF00078.22 OAJ05418.1 - 5.7e-16 58.5 0.0 1e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05418.1 - 2.5e-10 40.4 0.0 6.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ05418.1 - 0.00056 20.3 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ05418.1 - 0.052 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 OAJ05418.1 - 0.16 12.0 0.3 0.41 10.7 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein DUF303 PF03629.13 OAJ05418.1 - 0.23 10.6 0.0 0.41 9.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF303) Tom22 PF04281.8 OAJ05420.1 - 0.098 12.1 2.5 0.065 12.7 0.4 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 TMEM51 PF15345.1 OAJ05421.1 - 1.6e-05 24.7 0.7 5.6e-05 22.9 0.3 1.8 1 1 1 2 2 2 1 Transmembrane protein 51 Shisa PF13908.1 OAJ05421.1 - 0.00029 21.0 0.2 0.00047 20.3 0.2 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 OAJ05421.1 - 0.00086 19.0 0.1 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 OAJ05421.1 - 0.0011 17.3 0.1 0.0017 16.7 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 OAJ05421.1 - 0.0036 17.6 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.2 OAJ05421.1 - 0.0075 15.5 0.3 0.0096 15.1 0.2 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Mid2 PF04478.7 OAJ05421.1 - 0.012 15.0 0.2 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4381 PF14316.1 OAJ05421.1 - 0.016 15.3 0.3 0.067 13.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) LRR19-TM PF15176.1 OAJ05421.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain TMEM237 PF15383.1 OAJ05421.1 - 0.022 13.9 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 0 Transmembrane protein 237 DUF3094 PF11293.3 OAJ05421.1 - 0.025 14.0 1.2 0.05 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) IncA PF04156.9 OAJ05421.1 - 0.025 14.1 1.8 0.041 13.4 1.2 1.2 1 0 0 1 1 1 0 IncA protein Chordopox_A33R PF05966.7 OAJ05421.1 - 0.025 13.3 0.2 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein V_ATPase_I PF01496.14 OAJ05421.1 - 0.026 12.3 0.0 0.034 12.0 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SCIMP PF15050.1 OAJ05421.1 - 0.053 13.4 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 SCIMP protein Tmemb_9 PF05434.6 OAJ05421.1 - 0.084 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM9 DUF3357 PF11837.3 OAJ05421.1 - 0.096 12.5 1.0 0.21 11.4 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Rifin_STEVOR PF02009.11 OAJ05421.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family CcmD PF04995.9 OAJ05421.1 - 0.12 12.1 0.9 0.34 10.6 0.6 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1049 PF06305.6 OAJ05421.1 - 0.15 11.5 1.8 0.25 10.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1180 PF06679.7 OAJ05421.1 - 5.7 6.7 8.8 0.095 12.5 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Beta_protein PF14350.1 OAJ05422.1 - 0.035 13.2 0.0 0.046 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta protein NIT PF08376.5 OAJ05422.1 - 0.04 13.4 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing IBR PF01485.16 OAJ05423.1 - 1.8e-16 59.7 36.6 1.7e-10 40.5 1.9 4.4 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 OAJ05423.1 - 4.2e-13 49.1 0.0 8e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 OAJ05423.1 - 3.8e-08 33.0 4.2 3.8e-08 33.0 2.9 4.3 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.1 OAJ05423.1 - 3.7e-07 30.0 7.8 3.7e-07 30.0 5.4 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ05423.1 - 9.3e-05 22.0 7.1 9.3e-05 22.0 4.9 4.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ05423.1 - 0.00013 21.6 2.9 0.00013 21.6 2.0 3.3 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.20 OAJ05423.1 - 0.00015 21.3 6.3 0.00015 21.3 4.3 4.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) LysR_substrate PF03466.15 OAJ05423.1 - 0.088 11.8 1.7 0.2 10.7 0.2 2.1 2 0 0 2 2 2 0 LysR substrate binding domain DUF4455 PF14643.1 OAJ05425.1 - 0.11 11.1 9.0 0.17 10.4 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4455) SET PF00856.23 OAJ05426.1 - 0.00011 22.5 0.1 0.037 14.3 0.0 2.5 3 0 0 3 3 3 2 SET domain SAF PF08666.7 OAJ05426.1 - 0.066 13.6 0.0 3.6 8.0 0.0 2.3 2 0 0 2 2 2 0 SAF domain Ribosomal_S3Ae PF01015.13 OAJ05427.1 - 4e-79 264.4 0.8 4.6e-79 264.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 OAJ05427.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pkinase PF00069.20 OAJ05428.1 - 2e-58 197.6 0.0 4.1e-53 180.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05428.1 - 7.9e-33 113.6 0.0 1.1e-29 103.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ05428.1 - 7.1e-06 25.1 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ05428.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ05428.1 - 0.02 13.9 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 OAJ05428.1 - 0.13 10.9 0.1 0.2 10.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 OAJ05428.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pinin_SDK_N PF04697.8 OAJ05431.1 - 0.13 12.3 1.6 0.2 11.6 0.1 2.0 2 0 0 2 2 2 0 pinin/SDK conserved region DUF4637 PF15470.1 OAJ05431.1 - 0.14 11.7 1.2 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) HECT PF00632.20 OAJ05432.1 - 1.2e-91 307.2 0.0 1.8e-91 306.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 OAJ05432.1 - 2.2e-32 110.5 13.8 1.6e-10 40.6 1.9 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 OAJ05432.1 - 4.4e-14 52.0 0.1 9.5e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain VanZ PF04892.7 OAJ05433.1 - 1.1e-06 28.6 1.4 2.4e-06 27.5 0.9 1.6 1 1 0 1 1 1 1 VanZ like family DUF1275 PF06912.6 OAJ05433.1 - 0.022 13.9 1.5 0.039 13.1 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) HEAT_2 PF13646.1 OAJ05434.1 - 1.7e-07 31.3 19.5 0.067 13.4 0.0 7.7 6 3 2 8 8 8 3 HEAT repeats Arm PF00514.18 OAJ05434.1 - 0.0013 18.4 1.9 0.027 14.2 0.1 4.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 OAJ05434.1 - 0.0051 16.7 29.4 0.13 12.4 0.1 9.8 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.1 OAJ05434.1 - 0.0056 17.1 22.8 0.7 10.4 0.2 8.0 6 1 1 7 7 7 2 HEAT-like repeat Urb2 PF10441.4 OAJ05434.1 - 0.053 13.1 0.3 0.36 10.3 0.0 2.5 2 0 0 2 2 2 0 Urb2/Npa2 family RhoGEF PF00621.15 OAJ05435.1 - 3e-16 59.8 0.0 5.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CDP-OH_P_transf PF01066.16 OAJ05436.1 - 1.6e-12 47.6 4.5 1.6e-12 47.6 3.1 3.2 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Cullin PF00888.17 OAJ05437.1 - 1.1e-149 499.6 0.0 8.2e-145 483.6 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 OAJ05437.1 - 4.6e-29 100.0 0.3 8.7e-29 99.1 0.2 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 OAJ05437.1 - 0.021 14.9 0.0 0.092 12.8 0.0 2.2 1 0 0 1 1 1 0 Penicillinase repressor Tctex-1 PF03645.8 OAJ05438.1 - 5e-10 39.1 0.0 6.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Complex1_LYR PF05347.10 OAJ05439.1 - 0.0066 16.2 0.3 0.016 15.0 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ05439.1 - 0.0075 16.4 1.4 0.017 15.3 0.2 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Phage_integrase PF00589.17 OAJ05442.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family Mito_fiss_reg PF05308.6 OAJ05442.1 - 1 8.7 7.0 0.86 8.9 0.6 2.8 3 0 0 3 3 3 0 Mitochondrial fission regulator zf-LYAR PF08790.6 OAJ05443.1 - 0.35 10.5 1.7 0.64 9.7 1.2 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger His_Phos_1 PF00300.17 OAJ05444.1 - 2.7e-16 60.0 0.6 4.8e-14 52.7 0.0 3.3 3 2 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Tnp_DNA_bind PF14706.1 OAJ05444.1 - 0.085 12.5 0.1 0.23 11.1 0.1 1.7 1 0 0 1 1 1 0 Transposase DNA-binding Molybdopterin PF00384.17 OAJ05445.1 - 3.9e-73 246.6 0.0 3.9e-37 128.0 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 OAJ05445.1 - 9.2e-18 63.8 0.0 3.5e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 OAJ05445.1 - 1.4e-16 59.4 0.0 3.1e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 OAJ05445.1 - 2.8e-13 49.8 0.0 8.1e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 OAJ05445.1 - 4e-08 32.8 1.9 4.6e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 OAJ05445.1 - 0.016 14.9 0.1 3.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FHA PF00498.21 OAJ05447.1 - 3.8e-05 23.7 0.0 8.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain HSP70 PF00012.15 OAJ05448.1 - 4.3e-260 863.8 13.2 4.9e-260 863.6 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ05448.1 - 2.7e-19 68.9 0.9 3.7e-17 61.9 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DDR PF08841.5 OAJ05448.1 - 0.0005 19.0 1.2 0.028 13.2 0.3 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 OAJ05448.1 - 0.015 14.9 0.0 0.055 13.0 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 OAJ05448.1 - 0.11 12.3 3.6 0.58 10.0 0.0 3.5 3 2 0 3 3 3 0 Cell division protein FtsA Spectrin PF00435.16 OAJ05448.1 - 0.21 11.8 6.1 3.5 7.9 0.3 2.8 3 0 0 3 3 3 0 Spectrin repeat Hydantoinase_A PF01968.13 OAJ05448.1 - 0.48 9.4 8.8 0.052 12.6 0.3 3.1 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase Uds1 PF15456.1 OAJ05448.1 - 1 9.3 6.7 0.13 12.2 0.8 2.1 2 0 0 2 2 2 0 Up-regulated During Septation AAA_23 PF13476.1 OAJ05448.1 - 1.9 8.7 9.1 0.27 11.5 3.1 1.8 2 0 0 2 2 2 0 AAA domain GCFC PF07842.7 OAJ05449.1 - 4.5e-69 232.8 13.7 6.2e-69 232.4 9.5 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 OAJ05449.1 - 4.3e-08 32.8 0.2 4.3e-08 32.8 0.1 3.0 3 0 0 3 3 3 1 G-patch domain TatD_DNase PF01026.16 OAJ05451.1 - 4.3e-48 163.7 0.0 6.5e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RVT_1 PF00078.22 OAJ05452.1 - 1.1e-17 64.1 0.0 2.4e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05452.1 - 2.9e-12 46.7 0.0 6.5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP PF00077.15 OAJ05452.1 - 0.00065 19.5 0.0 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 OAJ05452.1 - 0.00066 20.1 0.0 0.0022 18.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease CCDC142 PF14923.1 OAJ05452.1 - 0.31 9.2 0.0 0.48 8.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 ParA PF10609.4 OAJ05454.1 - 3.2e-31 107.0 0.0 7e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ05454.1 - 6.2e-10 38.7 0.2 5.7e-09 35.6 0.2 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ05454.1 - 8e-06 25.8 0.0 4.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ05454.1 - 0.00028 20.3 0.0 0.00053 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 OAJ05454.1 - 0.0003 19.9 1.2 0.003 16.6 0.2 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 OAJ05454.1 - 0.028 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 OAJ05454.1 - 0.031 13.8 0.1 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ05454.1 - 0.057 13.4 0.3 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain MipZ PF09140.6 OAJ05454.1 - 0.061 12.4 0.0 1.4 7.9 0.0 2.2 1 1 0 2 2 2 0 ATPase MipZ ICL PF00463.16 OAJ05459.1 - 3.2e-255 847.2 1.4 3.7e-255 847.1 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 OAJ05459.1 - 1.4e-09 37.5 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 OAJ05459.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Mad3_BUB1_I PF08311.7 OAJ05460.1 - 4.6e-34 116.9 0.8 7.3e-34 116.2 0.6 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 OAJ05460.1 - 2e-11 43.5 0.0 4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 OAJ05460.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Nucleoplasmin PF03066.10 OAJ05460.1 - 1.1 8.7 13.4 1 8.8 3.0 3.0 2 0 0 2 2 2 0 Nucleoplasmin Translin PF01997.11 OAJ05461.1 - 4e-41 140.8 0.1 5e-41 140.5 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.4 OAJ05461.1 - 0.045 13.8 0.1 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin PF00804.20 OAJ05461.1 - 0.12 12.5 0.2 0.69 10.0 0.0 2.0 2 0 0 2 2 2 0 Syntaxin EST1_DNA_bind PF10373.4 OAJ05462.1 - 6.3e-31 107.6 0.0 1.3e-29 103.2 0.0 2.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 OAJ05462.1 - 1.6e-08 34.6 0.0 6.5e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 OAJ05462.1 - 0.014 15.0 0.0 0.046 13.3 0.0 1.9 1 0 0 1 1 1 0 TPR repeat CDP-OH_P_transf PF01066.16 OAJ05463.1 - 3.6e-16 59.3 4.0 4.9e-16 58.8 2.5 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase NAD_binding_11 PF14833.1 OAJ05464.1 - 9.7e-32 109.5 0.1 1.7e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 OAJ05464.1 - 4.3e-31 107.9 0.0 9.2e-31 106.8 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 OAJ05464.1 - 0.031 14.7 0.0 0.096 13.1 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent LIM PF00412.17 OAJ05466.1 - 2.9e-16 59.2 8.8 0.00054 19.9 0.0 5.4 5 0 0 5 5 5 4 LIM domain Ras PF00071.17 OAJ05467.1 - 1e-53 181.0 0.0 1.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ05467.1 - 6.5e-17 62.1 0.0 8.4e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ05467.1 - 4.7e-06 25.9 0.0 7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ05467.1 - 0.0012 18.3 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF367 PF04034.8 OAJ05468.1 - 2.9e-43 146.5 0.0 3.9e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 OAJ05468.1 - 1.2e-13 50.3 0.1 2.2e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SURF2 PF05477.6 OAJ05468.1 - 2.8 7.0 14.4 4.3 6.3 4.9 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Ran_BP1 PF00638.13 OAJ05470.1 - 1.9e-51 173.1 1.9 3e-51 172.5 1.3 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 OAJ05470.1 - 2.9e-06 26.9 1.0 1.7e-05 24.4 0.7 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 OAJ05470.1 - 6.9e-05 22.4 0.1 8.9e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) MGC-24 PF05283.6 OAJ05470.1 - 0.21 11.3 2.5 0.27 11.0 1.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) FctA PF12892.2 OAJ05470.1 - 0.33 11.7 0.1 0.33 11.7 0.1 2.5 3 0 0 3 3 3 0 T surface-antigen of pili Glyco_tranf_2_3 PF13641.1 OAJ05471.1 - 8.1e-27 94.4 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 OAJ05471.1 - 2.5e-20 73.0 6.3 2.5e-20 73.0 4.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 OAJ05471.1 - 3.7e-11 42.6 0.0 5.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 OAJ05471.1 - 8.8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 RhoGAP PF00620.22 OAJ05472.1 - 7.9e-46 155.4 0.0 1.4e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 OAJ05472.1 - 6e-17 61.6 0.6 2.4e-16 59.6 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEAD PF00270.24 OAJ05473.1 - 1.9e-31 108.8 0.1 3.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ05473.1 - 1.9e-20 72.5 0.0 1.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ05473.1 - 7.3e-05 22.6 0.0 7.3e-05 22.6 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 OAJ05473.1 - 0.029 12.7 0.0 0.95 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) BUD22 PF09073.5 OAJ05473.1 - 1.3 8.0 44.0 2.2 7.2 30.5 1.3 1 0 0 1 1 1 0 BUD22 SAPS PF04499.10 OAJ05473.1 - 1.7 7.1 13.5 3.4 6.2 9.4 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.8 OAJ05473.1 - 6.3 4.8 39.8 11 4.0 27.6 1.2 1 0 0 1 1 1 0 Utp14 protein PCI PF01399.22 OAJ05474.1 - 4.8e-20 71.8 0.0 3.5e-19 69.0 0.0 2.4 2 1 0 2 2 2 1 PCI domain TPR_16 PF13432.1 OAJ05474.1 - 3.5e-05 24.3 11.6 0.086 13.5 1.7 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05474.1 - 8.5e-05 22.1 6.3 0.081 12.5 0.4 3.5 3 0 0 3 3 3 2 TPR repeat DUF627 PF04781.7 OAJ05474.1 - 0.0034 16.9 1.3 2.3 7.8 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF627) TPR_14 PF13428.1 OAJ05474.1 - 0.0047 17.4 8.2 1 10.1 0.1 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ05474.1 - 0.0081 16.4 9.1 0.065 13.5 0.6 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 OAJ05474.1 - 0.0087 16.2 1.3 0.16 12.1 0.3 3.1 2 1 0 3 3 3 1 Alkyl sulfatase dimerisation TPR_6 PF13174.1 OAJ05474.1 - 0.014 15.7 6.4 6.4 7.4 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ05474.1 - 0.024 14.7 3.2 2.5 8.2 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 OAJ05474.1 - 0.51 10.3 7.6 49 4.1 0.2 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ05474.1 - 9.7 6.3 11.0 1.4 9.1 1.3 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 OAJ05475.1 - 1.1e-51 174.6 1.8 1.6e-51 174.1 1.2 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 OAJ05475.1 - 4.1e-15 55.9 0.0 1.1e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain SAC3_GANP PF03399.11 OAJ05475.1 - 0.0055 16.2 0.2 0.0096 15.4 0.2 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 OAJ05475.1 - 0.023 14.4 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_23 PF13384.1 OAJ05475.1 - 0.032 13.9 0.2 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Selenoprotein_S PF06936.6 OAJ05475.1 - 0.053 13.0 0.7 0.73 9.3 0.3 2.2 2 0 0 2 2 2 0 Selenoprotein S (SelS) DUF2183 PF09949.4 OAJ05476.1 - 1e-24 86.3 0.0 2.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pribosyltran PF00156.22 OAJ05477.1 - 3.5e-17 62.2 0.1 5e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ05477.1 - 0.0037 16.4 0.0 0.0043 16.2 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase RVT_1 PF00078.22 OAJ05478.1 - 0.0071 15.7 0.0 0.051 12.9 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 OAJ05478.1 - 0.043 13.5 0.1 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like PDEase_II PF02112.10 OAJ05480.1 - 1.5e-41 142.4 0.0 1.8e-20 73.1 0.0 3.8 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 OAJ05480.1 - 0.0015 18.0 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain UBN2_2 PF14227.1 OAJ05481.1 - 2e-10 40.2 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ05481.1 - 9.6e-09 35.0 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 OAJ05481.1 - 4.8e-06 26.2 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 OAJ05481.1 - 0.00023 20.5 2.0 0.00051 19.3 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC_5 PF14787.1 OAJ05481.1 - 0.0081 15.6 0.8 0.015 14.8 0.5 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 OAJ05481.1 - 0.27 11.2 1.2 0.48 10.4 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 OAJ05482.1 - 7.3e-68 228.5 0.0 1.2e-67 227.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05482.1 - 7.7e-30 103.8 0.0 1.2e-28 99.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ05482.1 - 0.00011 21.6 0.6 0.00021 20.7 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 OAJ05482.1 - 0.00033 19.6 0.9 0.73 8.7 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 OAJ05482.1 - 0.00035 20.4 0.3 0.28 10.8 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ05482.1 - 0.068 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hist_deacetyl PF00850.14 OAJ05484.1 - 2.7e-91 306.1 0.0 4e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ05484.1 - 0.00066 19.1 0.0 0.0078 15.6 0.0 2.6 2 1 0 2 2 2 1 Arb2 domain PBP1_TM PF14812.1 OAJ05485.1 - 0.69 10.2 11.9 35 4.7 0.2 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_HII PF01351.13 OAJ05488.1 - 1e-40 139.5 0.0 5.2e-36 124.1 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease HII Tim54 PF11711.3 OAJ05488.1 - 5.4 5.5 5.7 8.4 4.8 3.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DNA_pol_A_exo1 PF01612.15 OAJ05489.1 - 9.4e-38 129.4 0.1 1.4e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 OAJ05489.1 - 5.3e-16 58.6 0.0 1.4e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 OAJ05489.1 - 2.6e-10 39.8 0.1 5.4e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF3292 PF11696.3 OAJ05489.1 - 0.093 10.5 8.2 0.62 7.8 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) WD40 PF00400.27 OAJ05490.1 - 2.4e-28 96.9 5.1 2.2e-06 27.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 OAJ05490.1 - 1.4e-05 24.8 0.3 2.3e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 OAJ05490.1 - 0.0053 16.4 0.1 1.2 8.7 0.0 3.3 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.7 OAJ05490.1 - 0.0055 16.1 0.0 3 7.1 0.0 2.7 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Mannosyl_trans PF05007.8 OAJ05491.1 - 1.8e-53 181.8 17.1 3.4e-49 167.8 9.5 3.5 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) Piwi PF02171.12 OAJ05492.1 - 2e-74 250.3 0.0 2.9e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 OAJ05492.1 - 9.3e-16 57.3 0.0 1.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 OAJ05492.1 - 3.6e-09 35.8 0.3 8.5e-09 34.6 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Alpha-amyl_C2 PF07821.7 OAJ05492.1 - 0.15 11.9 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain E1_dh PF00676.15 OAJ05493.1 - 1.5e-115 385.0 0.5 1.8e-115 384.7 0.4 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 OAJ05493.1 - 1.7e-05 23.8 0.0 3.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 OAJ05493.1 - 0.00043 19.8 4.7 0.00088 18.8 1.3 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Herpes_UL32 PF06070.6 OAJ05493.1 - 0.036 12.5 0.8 0.045 12.2 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Syntaxin-18_N PF10496.4 OAJ05494.1 - 2.9e-06 27.0 0.4 4.3e-05 23.2 0.0 2.9 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Speriolin_N PF15058.1 OAJ05494.1 - 0.059 13.2 5.3 0.053 13.4 2.6 1.8 1 1 0 1 1 1 0 Speriolin N terminus Abhydrolase_3 PF07859.8 OAJ05495.1 - 1.4e-28 99.9 0.0 1.8e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 OAJ05495.1 - 1.9e-07 30.5 0.0 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 OAJ05495.1 - 0.0004 19.8 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 OAJ05495.1 - 0.00075 19.2 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ05495.1 - 0.035 13.8 0.0 0.28 10.8 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.20 OAJ05495.1 - 0.1 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) SHS2_Rpb7-N PF03876.12 OAJ05496.1 - 5.5e-14 52.0 0.0 8.9e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ05496.1 - 9.7e-11 41.6 0.1 1.4e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 OAJ05496.1 - 0.082 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 MRP-L20 PF12824.2 OAJ05497.1 - 5.5e-20 71.9 0.2 9.9e-20 71.1 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 APG12 PF04110.8 OAJ05498.1 - 5.7e-32 109.7 0.0 7.1e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 OAJ05498.1 - 0.0038 17.1 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like FliP PF00813.15 OAJ05498.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 FliP family Phage_integrase PF00589.17 OAJ05499.1 - 3e-06 27.0 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ05499.1 - 0.032 14.3 1.2 0.11 12.7 0.0 2.3 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 OAJ05499.1 - 0.042 14.1 0.0 0.088 13.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SNARE_assoc PF09335.6 OAJ05503.1 - 1.4e-14 54.3 1.9 2.6e-14 53.4 1.3 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4271 PF14093.1 OAJ05503.1 - 0.0075 15.9 0.2 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DUF95 PF01944.12 OAJ05503.1 - 0.28 10.7 3.2 2.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF95 FRG1 PF06229.7 OAJ05504.1 - 3.5e-20 72.2 1.2 8.5e-09 35.1 0.0 3.3 2 1 1 3 3 3 3 FRG1-like family Fascin PF06268.8 OAJ05504.1 - 3.7e-06 26.9 0.0 0.037 14.1 0.0 2.4 2 0 0 2 2 2 2 Fascin domain ROKNT PF08067.6 OAJ05504.1 - 0.16 11.8 0.4 0.63 9.9 0.3 2.0 2 0 0 2 2 2 0 ROKNT (NUC014) domain CAP_GLY PF01302.20 OAJ05505.1 - 8.6e-19 67.0 0.1 1.7e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 OAJ05505.1 - 9.8e-06 25.0 10.8 0.004 16.7 0.3 5.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ05505.1 - 0.0099 15.6 6.7 0.4 10.4 0.3 4.1 4 2 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 OAJ05505.1 - 9.4 6.7 7.5 2.6e+02 2.3 0.0 4.9 5 1 1 6 6 6 0 Leucine Rich Repeat Thioredoxin PF00085.15 OAJ05506.1 - 7.1e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin PLDc PF00614.17 OAJ05507.1 - 1.3e-16 59.7 0.3 3e-07 30.0 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 OAJ05507.1 - 2.4e-11 43.4 0.0 3.7e-07 29.9 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 OAJ05507.1 - 9.9e-09 34.9 0.0 3.1e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 PX domain PH PF00169.24 OAJ05507.1 - 0.0036 17.4 0.1 0.019 15.1 0.1 2.1 1 1 0 1 1 1 1 PH domain Abhydrolase_5 PF12695.2 OAJ05508.1 - 9.3e-05 22.2 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 OAJ05508.1 - 0.00023 20.5 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 OAJ05508.1 - 0.00061 19.7 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 OAJ05508.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PBP1_TM PF14812.1 OAJ05508.1 - 0.07 13.4 0.5 0.07 13.4 0.3 5.6 6 0 0 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PUF PF00806.14 OAJ05509.1 - 4.7e-17 60.4 0.4 2.6e-07 29.7 0.0 5.8 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat ORC4_C PF14629.1 OAJ05511.1 - 7.1e-24 84.3 0.0 1.5e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 OAJ05511.1 - 5.9e-07 29.6 0.2 5.9e-07 29.6 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain CDC45 PF02724.9 OAJ05511.1 - 1.1 7.1 9.7 0.88 7.5 0.9 2.3 2 0 0 2 2 2 0 CDC45-like protein DUF4149 PF13664.1 OAJ05512.1 - 8.1e-20 70.7 2.9 8.1e-20 70.7 2.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Pro_isomerase PF00160.16 OAJ05514.1 - 1.7e-46 158.2 0.0 4.5e-46 156.8 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 OAJ05514.1 - 4.7e-12 45.2 1.9 0.0061 16.3 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 OAJ05514.1 - 0.054 11.7 0.2 0.23 9.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain HpaP PF09483.5 OAJ05514.1 - 2.8 7.8 6.3 5 7.0 4.4 1.4 1 0 0 1 1 1 0 Type III secretion protein (HpaP) AT_hook PF02178.14 OAJ05516.1 - 1.1 9.1 8.0 2.2 8.2 5.5 1.5 1 0 0 1 1 1 0 AT hook motif Prefoldin_2 PF01920.15 OAJ05517.1 - 5.8e-17 61.3 7.6 7.5e-17 61.0 5.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 OAJ05517.1 - 0.028 14.2 1.0 0.028 14.2 0.7 2.1 2 0 0 2 2 2 0 Tropomyosin like Sec23_trunk PF04811.10 OAJ05517.1 - 0.07 12.4 0.8 0.12 11.7 0.6 1.3 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain RasGAP_C PF03836.10 OAJ05517.1 - 0.077 12.6 7.9 0.1 12.2 0.1 2.8 2 1 1 3 3 3 0 RasGAP C-terminus FliD_C PF07195.7 OAJ05517.1 - 0.16 11.2 4.0 0.1 11.9 0.3 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Antimicrobial_3 PF08025.6 OAJ05517.1 - 0.27 11.0 1.3 0.7 9.6 0.9 1.7 1 0 0 1 1 1 0 Spider antimicrobial peptide DUF3509 PF12021.3 OAJ05517.1 - 0.41 10.4 4.8 6 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Radical_SAM_N PF08497.5 OAJ05517.1 - 0.45 9.3 2.1 0.48 9.3 1.5 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal NPV_P10 PF05531.7 OAJ05517.1 - 0.98 9.7 3.9 1.8 8.8 0.1 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.6 OAJ05517.1 - 1.9 8.2 6.9 2.1 8.0 0.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Cortex-I_coil PF09304.5 OAJ05517.1 - 4 7.5 8.3 1.3 9.0 0.2 2.3 2 1 0 2 2 2 0 Cortexillin I, coiled coil ADIP PF11559.3 OAJ05517.1 - 4.3 7.2 10.2 7.5 6.4 2.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cupin_5 PF06172.6 OAJ05518.1 - 1.6e-15 57.2 0.0 5.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily (DUF985) GATA PF00320.22 OAJ05519.1 - 3.3e-15 55.1 7.8 8.3e-15 53.8 5.4 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 OAJ05519.1 - 0.012 14.9 1.5 0.022 14.0 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 OAJ05519.1 - 0.079 12.2 0.8 0.18 11.0 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L6 PF00347.18 OAJ05521.1 - 4.5e-24 84.7 1.9 5.1e-11 42.9 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Acyl-CoA_dh_1 PF00441.19 OAJ05522.1 - 2.7e-49 167.1 7.6 2.8e-49 167.0 4.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ05522.1 - 1.5e-25 89.9 1.6 4.3e-25 88.4 0.2 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ05522.1 - 2.2e-25 87.9 0.4 5.5e-25 86.6 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ05522.1 - 5.5e-19 68.7 5.8 5.5e-19 68.7 4.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 OAJ05522.1 - 4.1e-05 23.1 0.2 0.00016 21.1 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DEAD PF00270.24 OAJ05523.1 - 4e-33 114.2 0.1 6.9e-32 110.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ05523.1 - 2.4e-22 78.5 0.0 7e-22 77.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIID_20kDa PF03847.8 OAJ05524.1 - 4.2e-32 110.2 0.7 6.3e-32 109.6 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 OAJ05524.1 - 0.0059 16.6 0.1 0.013 15.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Occludin_ELL PF07303.8 OAJ05524.1 - 0.1 13.3 0.0 0.1 13.3 0.0 2.2 3 0 0 3 3 3 0 Occludin homology domain PAT1 PF09770.4 OAJ05524.1 - 0.39 8.8 37.0 0.61 8.2 25.7 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DASH_Ask1 PF08655.5 OAJ05525.1 - 1.9e-28 98.0 0.0 3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PIF1 PF05970.9 OAJ05530.1 - 1.8e-21 76.5 0.0 4.2e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ05530.1 - 7.5e-12 45.2 0.7 2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ05530.1 - 1.9e-08 33.9 0.1 1e-07 31.6 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ05530.1 - 5.2e-05 23.0 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ05530.1 - 0.0019 18.2 0.0 0.0075 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 OAJ05530.1 - 0.078 12.7 0.3 0.88 9.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAJ05530.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 OAJ05530.1 - 0.086 12.3 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 OAJ05530.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ05530.1 - 0.21 11.0 0.0 0.59 9.6 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Apolipoprotein PF01442.13 OAJ05531.1 - 0.00046 19.7 0.6 0.00058 19.4 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Mer2 PF09074.5 OAJ05531.1 - 0.025 14.4 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Mer2 CorA PF01544.13 OAJ05531.1 - 0.051 12.6 0.5 0.065 12.2 0.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PKK PF12474.3 OAJ05531.1 - 0.069 12.8 0.1 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Polo kinase kinase DUF883 PF05957.8 OAJ05531.1 - 0.16 12.3 5.9 0.079 13.3 1.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HSP90 PF00183.13 OAJ05534.1 - 3.2e-10 39.0 0.0 4.2e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Hsp90 protein Nop14 PF04147.7 OAJ05537.1 - 0.33 8.8 1.6 0.45 8.3 1.1 1.1 1 0 0 1 1 1 0 Nop14-like family HSP90 PF00183.13 OAJ05539.1 - 5.5e-15 54.7 0.5 2.1e-09 36.3 0.0 2.0 1 1 1 2 2 2 2 Hsp90 protein Snf7 PF03357.16 OAJ05540.1 - 9.1e-21 73.9 1.9 1.5e-20 73.3 1.3 1.3 1 0 0 1 1 1 1 Snf7 Upf2 PF04050.9 OAJ05540.1 - 0.0056 16.4 0.5 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 Up-frameshift suppressor 2 DUF1537 PF07005.6 OAJ05540.1 - 0.079 12.6 8.9 0.064 12.9 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF1537 Phage_GPO PF05929.6 OAJ05540.1 - 0.091 12.0 0.6 0.22 10.7 0.2 1.8 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.7 OAJ05540.1 - 2.6 7.8 5.7 2.9 7.6 0.1 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CAP_GLY PF01302.20 OAJ05541.1 - 2.6e-15 55.8 0.2 4.4e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF812 PF05667.6 OAJ05541.1 - 0.001 17.6 13.0 0.001 17.6 9.0 4.9 3 1 2 5 5 5 1 Protein of unknown function (DUF812) zf-CCHC_2 PF13696.1 OAJ05541.1 - 0.57 9.7 3.1 4.7 6.7 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ05541.1 - 1.1 8.9 6.9 3.4 7.3 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L1 PF00687.16 OAJ05542.1 - 7.2e-46 156.2 0.0 2.5e-45 154.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family CarD_CdnL_TRCF PF02559.11 OAJ05542.1 - 0.059 13.4 0.6 0.15 12.1 0.4 1.7 1 0 0 1 1 1 0 CarD-like/TRCF domain Nucleo_P87 PF07267.6 OAJ05542.1 - 0.15 10.7 5.7 0.25 9.9 3.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.8 OAJ05542.1 - 0.35 10.7 12.4 0.033 14.1 3.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 OAJ05542.1 - 0.36 10.7 17.9 0.65 9.9 12.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FLO_LFY PF01698.11 OAJ05542.1 - 0.57 8.9 8.5 0.85 8.4 5.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PGC7_Stella PF15549.1 OAJ05542.1 - 0.67 9.9 6.9 0.056 13.4 1.0 2.0 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain BTV_NS2 PF04514.7 OAJ05542.1 - 4.3 6.1 12.0 6.6 5.5 8.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Phosphodiest PF01663.17 OAJ05543.1 - 1.6e-54 185.6 0.0 4.3e-52 177.6 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase XdhC_CoxI PF02625.11 OAJ05543.1 - 0.0025 17.3 0.1 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 XdhC and CoxI family CENP-T PF15511.1 OAJ05543.1 - 0.15 11.2 15.8 0.072 12.3 9.4 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Zn_clus PF00172.13 OAJ05544.1 - 9.9e-09 34.9 7.7 1.6e-08 34.2 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rad17 PF03215.10 OAJ05545.1 - 2.4e-39 135.3 0.0 2.8e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 OAJ05545.1 - 1.1e-05 25.4 0.3 7.3e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ05545.1 - 0.0011 19.1 0.0 0.0045 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ05545.1 - 0.0095 15.4 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 OAJ05545.1 - 0.022 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 OAJ05545.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 OAJ05545.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ05545.1 - 0.065 14.0 0.0 0.22 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 OAJ05545.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.1 OAJ05545.1 - 0.23 11.3 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Asp PF00026.18 OAJ05546.1 - 1.9e-32 112.8 0.0 3.7e-23 82.2 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Ribosomal_L36e PF01158.13 OAJ05547.1 - 4.9e-37 125.8 6.4 5.7e-37 125.6 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e L51_S25_CI-B8 PF05047.11 OAJ05547.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DNase_NucA_NucB PF14040.1 OAJ05549.1 - 3.6e-26 91.5 0.8 5.5e-26 90.9 0.5 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB RNB PF00773.14 OAJ05555.1 - 6.1e-96 321.5 0.0 9.9e-96 320.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain IGR PF09597.5 OAJ05556.1 - 9.3e-08 31.8 0.1 3.4e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 IGR protein motif APH PF01636.18 OAJ05557.1 - 5.8e-17 62.2 0.5 5.8e-17 62.2 0.3 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 OAJ05558.1 - 1.4e-09 37.4 0.0 2.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05558.1 - 0.0088 15.1 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RAMP PF04901.8 OAJ05558.1 - 0.11 12.2 0.7 0.25 11.1 0.3 1.8 1 1 0 1 1 1 0 Receptor activity modifying family PHD PF00628.24 OAJ05559.1 - 0.0021 17.6 9.3 0.0051 16.4 6.5 1.6 1 0 0 1 1 1 1 PHD-finger TPR_12 PF13424.1 OAJ05560.1 - 1.5e-10 40.9 23.6 0.0007 19.4 0.1 8.2 6 3 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05560.1 - 1.4e-08 34.0 15.2 0.24 11.4 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05560.1 - 3.7e-06 26.4 11.8 0.035 13.7 0.1 6.7 5 2 2 7 7 7 3 TPR repeat TPR_19 PF14559.1 OAJ05560.1 - 1.7e-05 25.0 9.7 1.6 9.1 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ05560.1 - 0.0001 21.8 15.2 6.9 6.7 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ05560.1 - 0.00022 21.3 0.2 0.41 10.8 0.0 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 OAJ05560.1 - 0.00052 19.5 9.1 3 7.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 OAJ05560.1 - 0.064 13.2 4.1 38 4.5 0.0 5.2 6 0 0 6 6 5 0 PPR repeat DUF799 PF05643.6 OAJ05560.1 - 0.08 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) TPR_14 PF13428.1 OAJ05560.1 - 0.15 12.7 21.9 85 4.2 0.0 9.0 8 2 1 9 9 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ05560.1 - 0.5 10.9 12.2 3.3 8.3 0.0 6.6 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05560.1 - 0.59 10.8 0.0 0.59 10.8 0.0 6.5 6 2 1 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ05560.1 - 2 8.4 22.1 2.7 8.0 0.2 6.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ05560.1 - 5.3 7.7 22.1 4.1 8.1 0.7 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat SLT PF01464.15 OAJ05561.1 - 6.3e-05 22.4 0.1 0.00085 18.8 0.0 2.4 1 1 0 1 1 1 1 Transglycosylase SLT domain DUF2201_N PF13203.1 OAJ05561.1 - 0.022 13.9 2.4 0.041 13.0 1.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 OAJ05561.1 - 0.38 8.7 3.0 0.58 8.1 1.8 1.4 2 0 0 2 2 2 0 CDC45-like protein Glypican PF01153.14 OAJ05561.1 - 3.3 6.2 4.9 4.7 5.7 3.4 1.2 1 0 0 1 1 1 0 Glypican Glyco_hydro_cc PF11790.3 OAJ05562.1 - 2.3e-52 177.7 2.8 2.8e-52 177.5 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core FAT PF02259.18 OAJ05563.1 - 3.7e-66 223.4 2.0 3.7e-66 223.4 1.4 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 OAJ05563.1 - 1.7e-23 83.3 0.0 6.9e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 OAJ05563.1 - 0.012 15.0 0.4 0.027 13.9 0.3 1.7 1 0 0 1 1 1 0 FATC domain RINT1_TIP1 PF04437.8 OAJ05564.1 - 6.8e-43 146.9 0.0 4.2e-30 104.7 0.0 3.8 2 1 0 2 2 2 2 RINT-1 / TIP-1 family BCDHK_Adom3 PF10436.4 OAJ05565.1 - 5.2e-42 143.1 0.0 7.4e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 OAJ05565.1 - 4.1e-13 49.0 0.0 6.3e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 OAJ05565.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AFG1_ATPase PF03969.11 OAJ05566.1 - 5.7e-53 179.9 0.0 1.7e-39 135.6 0.0 3.8 3 2 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.1 OAJ05566.1 - 1.6e-08 34.7 0.1 7.8e-08 32.5 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ05566.1 - 1.4e-05 25.2 0.0 0.029 14.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 OAJ05566.1 - 0.00014 21.6 0.0 0.035 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ05566.1 - 0.001 19.2 0.0 0.021 14.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAJ05566.1 - 0.0041 16.6 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 OAJ05566.1 - 0.0056 15.8 0.0 0.017 14.3 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 OAJ05566.1 - 0.0058 16.6 0.0 4 7.4 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.1 OAJ05566.1 - 0.014 15.1 1.9 0.04 13.6 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain AAA_14 PF13173.1 OAJ05566.1 - 0.016 15.1 0.0 12 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.8 OAJ05566.1 - 0.35 9.5 0.0 16 4.0 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus DUF2335 PF10097.4 OAJ05566.1 - 2.5 7.7 5.8 9.6 5.9 4.0 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Methyltransf_11 PF08241.7 OAJ05567.1 - 4.4e-09 36.7 0.0 9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ05567.1 - 4.2e-06 26.5 0.0 5.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ05567.1 - 2e-05 24.8 0.1 4.4e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ05567.1 - 0.00015 22.1 0.0 0.00047 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05567.1 - 0.00016 22.2 0.1 0.00022 21.7 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ05567.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ05567.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fun_ATP-synt_8 PF05933.8 OAJ05568.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) MOR2-PAG1_N PF14222.1 OAJ05569.1 - 2e-110 370.0 0.0 3.2e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 OAJ05569.1 - 4.9e-60 203.5 5.8 9.5e-60 202.5 1.4 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 OAJ05569.1 - 1.1e-21 76.3 0.4 3.3e-07 28.3 0.0 4.9 5 0 0 5 5 5 4 Cell morphogenesis central region Glyco_transf_22 PF03901.12 OAJ05571.1 - 2.2e-28 99.4 9.0 3e-28 98.9 6.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family WD40 PF00400.27 OAJ05572.1 - 1.6e-08 34.0 1.2 0.00023 20.9 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat BUD22 PF09073.5 OAJ05573.1 - 0.078 12.0 21.4 0.15 11.0 14.8 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 OAJ05573.1 - 0.11 10.5 17.6 0.19 9.7 12.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 OAJ05573.1 - 0.61 9.8 24.8 1.2 9.0 17.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.7 OAJ05573.1 - 1.3 6.8 36.9 2.2 6.1 25.6 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 OAJ05573.1 - 1.4 7.1 26.9 2.1 6.6 18.7 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.8 OAJ05573.1 - 2.8 7.7 22.1 0.15 11.9 10.3 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATPgrasp_Ter PF15632.1 OAJ05574.1 - 7.3e-08 31.5 0.0 2.6e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 OAJ05574.1 - 1.6e-06 27.9 0.0 3.5e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Abhydrolase_5 PF12695.2 OAJ05574.1 - 0.044 13.5 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ05574.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase LEAP-2 PF07359.6 OAJ05575.1 - 0.022 14.4 0.1 0.022 14.4 0.1 3.7 2 1 1 4 4 4 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) UPF0506 PF11703.3 OAJ05575.1 - 0.06 13.3 34.7 1.1 9.2 1.0 3.6 3 1 0 3 3 3 0 UPF0506 Pox_E10 PF04805.7 OAJ05575.1 - 0.23 11.0 1.9 0.43 10.1 1.3 1.5 1 0 0 1 1 1 0 E10-like protein conserved region TPR_1 PF00515.23 OAJ05576.1 - 0.00044 19.7 0.5 0.01 15.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 OAJ05576.1 - 0.00049 20.1 2.5 0.097 12.7 0.0 3.9 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_12 PF13424.1 OAJ05576.1 - 0.00085 19.2 16.7 1.2 9.1 0.1 6.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05576.1 - 0.0043 16.8 9.8 0.028 14.3 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05576.1 - 0.0066 16.0 14.4 0.015 14.9 0.0 5.8 6 1 1 7 7 7 1 TPR repeat TPR_7 PF13176.1 OAJ05576.1 - 0.0073 16.0 0.9 1.4 8.9 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05576.1 - 0.0082 15.8 1.2 0.15 11.8 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ05576.1 - 0.026 14.3 0.6 4.4 7.2 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 OAJ05576.1 - 0.23 11.8 12.1 4.7 7.6 0.5 5.6 4 1 0 4 4 4 0 Tetratricopeptide repeat AMP-binding PF00501.23 OAJ05577.1 - 1.1e-26 93.2 0.0 3.1e-26 91.7 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ05577.1 - 9.1e-25 87.0 0.0 1.6e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ05577.1 - 1.3e-09 38.2 0.2 4e-09 36.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 OAJ05577.1 - 4.7e-09 36.0 0.0 9.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 OAJ05577.1 - 0.012 15.3 0.2 0.059 13.0 0.1 2.2 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.12 OAJ05577.1 - 0.026 13.3 0.0 1.1 8.1 0.0 2.6 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 OAJ05577.1 - 0.088 12.7 0.2 0.32 10.9 0.2 2.0 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 OAJ05577.1 - 0.099 11.3 0.0 0.56 8.8 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ05577.1 - 0.49 9.2 0.0 0.8 8.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHQ_synthase PF01761.15 OAJ05578.1 - 9.2e-48 162.4 0.0 1.2e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 OAJ05578.1 - 6.5e-12 45.2 0.0 9.3e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldo_ket_red PF00248.16 OAJ05579.1 - 3.6e-63 213.0 0.0 4.5e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 OAJ05580.1 - 2e-26 92.4 0.0 7.1e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ05580.1 - 2.7e-08 33.5 6.1 4.6e-08 32.8 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 OAJ05581.1 - 1.5e-38 129.2 11.4 6.5e-09 35.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Sof1 PF04158.9 OAJ05581.1 - 8e-26 89.8 11.8 1.2e-25 89.3 8.2 1.3 1 0 0 1 1 1 1 Sof1-like domain Nucleoporin_N PF08801.6 OAJ05581.1 - 0.0063 15.2 0.2 0.91 8.1 0.0 2.9 2 2 0 2 2 2 2 Nup133 N terminal like Me-amine-dh_H PF06433.6 OAJ05581.1 - 0.059 11.9 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) BBS2_Mid PF14783.1 OAJ05581.1 - 0.06 13.1 0.0 5.3 6.8 0.0 3.4 3 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Methyltransf_3 PF01596.12 OAJ05584.1 - 7.5e-53 178.6 0.0 1.2e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 OAJ05584.1 - 1.4e-12 48.3 0.1 3.2e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ05584.1 - 2.1e-08 34.1 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05584.1 - 0.00036 21.0 0.0 0.00063 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ05584.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ribosomal_S26e PF01283.14 OAJ05591.1 - 4.9e-52 174.9 7.7 6.1e-52 174.6 5.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 OAJ05591.1 - 0.003 17.9 0.7 0.0055 17.0 0.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 OAJ05591.1 - 0.049 14.3 0.5 0.093 13.4 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain DUF1918 PF08940.6 OAJ05591.1 - 0.049 12.9 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_8 PF13183.1 OAJ05591.1 - 0.057 13.4 0.6 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 OAJ05591.1 - 0.06 13.1 2.5 0.14 12.0 1.7 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 OAJ05591.1 - 0.45 10.8 3.1 3.4 8.0 2.7 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 OAJ05591.1 - 1.1 9.0 4.8 0.29 10.8 0.7 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 OAJ05591.1 - 2.7 8.0 6.5 0.22 11.4 0.9 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C3HC4_2 PF13923.1 OAJ05593.1 - 1.7e-06 27.9 8.9 1.7e-06 27.9 6.2 3.2 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ05593.1 - 8.9e-06 25.4 9.8 8.9e-06 25.4 6.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ05593.1 - 2.2e-05 24.0 5.1 2.2e-05 24.0 3.6 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ05593.1 - 3.8e-05 23.2 11.9 3.8e-05 23.2 8.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ05593.1 - 7.8e-05 22.3 7.5 7.8e-05 22.3 5.2 2.7 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ05593.1 - 0.00036 20.3 5.1 0.00036 20.3 3.5 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ05593.1 - 0.00088 18.9 1.1 0.00088 18.9 0.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger DEAD PF00270.24 OAJ05594.1 - 2.4e-37 128.0 0.1 5.6e-37 126.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ05594.1 - 1.7e-24 85.4 0.0 8.4e-24 83.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ05594.1 - 5.2e-06 26.4 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 OAJ05594.1 - 0.037 13.0 0.0 0.091 11.8 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ETF_QO PF05187.8 OAJ05597.1 - 3.4e-39 133.2 0.0 8.4e-39 131.9 0.0 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 OAJ05597.1 - 6e-08 31.9 0.2 5.7e-05 22.1 0.2 2.3 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ05597.1 - 3.3e-07 29.5 6.5 0.0012 17.8 0.1 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ05597.1 - 1.4e-06 28.1 0.0 4.4e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ05597.1 - 8.5e-05 22.5 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ05597.1 - 9e-05 21.1 0.2 0.00014 20.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 OAJ05597.1 - 0.00068 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 OAJ05597.1 - 0.0012 19.1 1.3 0.0032 17.8 0.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.1 OAJ05597.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_10 PF13237.1 OAJ05597.1 - 0.0023 17.7 0.8 0.0041 16.8 0.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.2 OAJ05597.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 OAJ05597.1 - 0.0033 16.5 0.0 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 OAJ05597.1 - 0.0037 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ05597.1 - 0.0074 16.6 0.2 0.26 11.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_21 PF14697.1 OAJ05597.1 - 0.015 15.1 1.3 0.03 14.1 0.9 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.1 OAJ05597.1 - 0.024 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.2 OAJ05597.1 - 0.055 13.4 0.4 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_binding_3 PF01494.14 OAJ05597.1 - 0.097 11.7 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Fer4_6 PF12837.2 OAJ05597.1 - 1.5 8.7 4.8 0.45 10.4 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DPBB_1 PF03330.13 OAJ05598.1 - 3.2e-06 27.0 0.5 1.2e-05 25.2 0.4 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ05598.1 - 5.1e-06 26.1 0.2 0.034 13.8 0.1 2.4 2 0 0 2 2 2 2 Barwin family Hexokinase_2 PF03727.11 OAJ05599.1 - 8e-81 270.8 0.0 1.2e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 OAJ05599.1 - 3.1e-66 222.6 0.0 5.1e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Sigma_reg_N PF13800.1 OAJ05600.1 - 0.037 14.0 0.0 0.037 14.0 0.0 2.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal TB2_DP1_HVA22 PF03134.14 OAJ05601.1 - 1.2e-22 79.4 5.8 1.1e-19 69.9 1.4 2.3 2 0 0 2 2 2 2 TB2/DP1, HVA22 family CHD5 PF04420.9 OAJ05602.1 - 1.5e-41 141.7 0.1 2e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 CHD5-like protein Snapin_Pallidin PF14712.1 OAJ05602.1 - 0.089 13.1 0.9 0.15 12.4 0.6 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF3671 PF12420.3 OAJ05602.1 - 0.095 12.6 0.0 0.45 10.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function FYVE_2 PF02318.11 OAJ05603.1 - 0.026 14.4 3.5 0.87 9.5 0.1 2.1 1 1 1 2 2 2 0 FYVE-type zinc finger zf-RING_3 PF14369.1 OAJ05603.1 - 0.11 12.5 0.9 0.11 12.5 0.6 1.9 2 0 0 2 2 2 0 zinc-finger DUF3716 PF12511.3 OAJ05603.1 - 0.15 11.6 3.7 0.24 11.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_Tnp_IS1595 PF12760.2 OAJ05603.1 - 0.41 10.4 6.8 3.2 7.6 4.7 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DZR PF12773.2 OAJ05603.1 - 0.43 10.4 0.2 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 OAJ05603.1 - 0.67 9.7 3.7 18 5.2 0.1 2.5 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-Sec23_Sec24 PF04810.10 OAJ05603.1 - 0.9 9.1 5.3 1.1 8.9 0.4 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 OAJ05603.1 - 1.3 8.9 7.3 1.4 8.8 0.3 2.8 2 1 0 2 2 2 0 Rubredoxin zf-AD PF07776.10 OAJ05603.1 - 1.3 9.0 4.1 1.1 9.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) SIR2 PF02146.12 OAJ05604.1 - 6.2e-54 182.4 0.0 1.2e-53 181.4 0.0 1.5 2 0 0 2 2 2 1 Sir2 family HSP70 PF00012.15 OAJ05605.1 - 4.4e-266 883.5 8.8 5e-266 883.4 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ05605.1 - 8.6e-15 54.1 0.5 7.4e-13 47.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 OAJ05605.1 - 0.0055 16.5 2.2 1.3 8.8 0.1 3.2 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 OAJ05605.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF1484 PF07363.6 OAJ05605.1 - 0.099 12.9 0.2 0.42 10.9 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) SIR2 PF02146.12 OAJ05606.1 - 3.1e-16 59.5 0.0 7.7e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Sir2 family DUF500 PF04366.7 OAJ05607.1 - 5.1e-39 132.6 0.3 1.3e-38 131.2 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF500) VGCC_beta4Aa_N PF12052.3 OAJ05607.1 - 0.55 10.1 3.6 5.6 6.9 0.4 2.6 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal PAT1 PF09770.4 OAJ05607.1 - 7.2 4.7 22.5 13 3.8 15.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3BGR PF04908.10 OAJ05608.1 - 1.9e-14 53.4 0.0 4.4e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Methyltransf_18 PF12847.2 OAJ05609.1 - 7.2e-07 29.7 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ05609.1 - 5.8e-06 26.7 0.0 1.1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ05609.1 - 0.00012 21.7 0.0 0.00051 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ05609.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ05609.1 - 0.00018 21.9 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ05609.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Longin PF13774.1 OAJ05610.1 - 1.8e-15 56.2 0.2 4.8e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 OAJ05610.1 - 3.6e-14 52.1 0.9 3.6e-14 52.1 0.7 1.6 2 0 0 2 2 2 1 Synaptobrevin Cys_Met_Meta_PP PF01053.15 OAJ05611.1 - 3.5e-54 183.5 0.0 2e-47 161.3 0.0 2.3 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 OAJ05611.1 - 0.028 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_5 PF00266.14 OAJ05611.1 - 0.059 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V CRC_subunit PF08624.5 OAJ05613.1 - 9.8e-39 132.4 0.1 1.7e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TBX PF12598.3 OAJ05613.1 - 0.89 9.9 7.7 2.8 8.3 5.3 1.9 1 0 0 1 1 1 0 T-box transcription factor Orbi_NS3 PF01616.11 OAJ05615.1 - 1.8 7.4 5.4 0.62 8.9 1.5 1.8 2 0 0 2 2 2 0 Orbivirus NS3 Methyltransf_16 PF10294.4 OAJ05617.1 - 5.1e-09 35.8 0.0 1.3e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 OAJ05617.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0029 PF01205.14 OAJ05618.1 - 6.3e-23 80.5 0.0 3e-22 78.3 0.0 2.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 PH PF00169.24 OAJ05618.1 - 1.3e-06 28.5 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PH domain RWD PF05773.17 OAJ05618.1 - 0.034 14.0 0.0 0.15 11.9 0.0 2.1 1 1 0 1 1 1 0 RWD domain Daxx PF03344.10 OAJ05618.1 - 2.7 6.3 13.3 5.2 5.4 9.2 1.4 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 OAJ05620.1 - 0.00065 19.0 6.3 0.00082 18.7 4.3 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Pro_isomerase PF00160.16 OAJ05621.1 - 3.5e-44 150.7 0.0 5.5e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 OAJ05621.1 - 8.8e-09 34.8 7.8 0.00057 19.4 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 OAJ05621.1 - 1.6e-05 24.4 5.9 0.0056 16.5 0.5 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ05621.1 - 0.00052 19.5 3.3 0.01 15.4 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05621.1 - 0.017 14.8 2.4 0.027 14.2 0.4 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05621.1 - 0.14 12.9 6.3 0.98 10.1 3.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ05621.1 - 0.18 12.3 2.8 2.1 8.9 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 OAJ05623.1 - 1.9e-06 27.7 14.9 2.9e-06 27.1 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ05623.1 - 3.1e-06 26.7 9.8 4.6e-06 26.2 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ05623.1 - 5.9e-06 26.0 14.1 9.2e-06 25.3 9.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 OAJ05623.1 - 1.9e-05 24.2 13.4 3.1e-05 23.5 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ05623.1 - 4.1e-05 23.2 11.2 6.8e-05 22.5 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain XhlA PF10779.4 OAJ05623.1 - 0.00022 21.0 0.8 0.00048 19.9 0.6 1.6 1 0 0 1 1 1 1 Haemolysin XhlA zf-C3HC4_4 PF15227.1 OAJ05623.1 - 0.001 18.8 13.7 0.0018 18.0 9.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PAP1 PF08601.5 OAJ05623.1 - 0.003 17.3 2.3 0.0038 16.9 1.6 1.3 1 0 0 1 1 1 1 Transcription factor PAP1 Tropomyosin_1 PF12718.2 OAJ05623.1 - 0.0064 16.3 0.3 0.016 15.0 0.2 1.6 1 0 0 1 1 1 1 Tropomyosin like DUF3450 PF11932.3 OAJ05623.1 - 0.0092 15.2 0.6 0.0092 15.2 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Baculo_IE-1 PF05290.6 OAJ05623.1 - 0.0095 15.6 1.6 0.015 15.0 1.1 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) ADIP PF11559.3 OAJ05623.1 - 0.0096 15.8 0.7 0.0096 15.8 0.5 1.8 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 OAJ05623.1 - 0.015 15.0 0.7 0.043 13.6 0.5 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 OAJ05623.1 - 0.031 12.9 0.1 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RasGAP_C PF03836.10 OAJ05623.1 - 0.038 13.6 0.9 0.11 12.1 0.6 1.7 1 0 0 1 1 1 0 RasGAP C-terminus zf-rbx1 PF12678.2 OAJ05623.1 - 0.057 13.5 10.2 0.21 11.7 7.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger NPV_P10 PF05531.7 OAJ05623.1 - 0.06 13.6 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 OAJ05623.1 - 0.065 12.8 0.7 0.13 11.8 0.5 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 OAJ05623.1 - 0.08 12.4 1.1 0.16 11.4 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.6 OAJ05623.1 - 0.14 11.8 0.9 0.3 10.7 0.6 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF812 PF05667.6 OAJ05623.1 - 0.28 9.6 8.2 0.39 9.1 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 OAJ05623.1 - 0.3 8.9 0.1 0.41 8.4 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4472 PF14739.1 OAJ05623.1 - 0.31 11.5 2.7 0.26 11.7 0.2 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4472) SlyX PF04102.7 OAJ05623.1 - 0.44 10.9 3.7 0.15 12.4 0.3 1.9 2 0 0 2 2 1 0 SlyX DNA_pol_viral_N PF00242.12 OAJ05623.1 - 0.66 8.9 7.0 0.88 8.5 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Tmemb_cc2 PF10267.4 OAJ05623.1 - 1.4 7.4 8.6 2.6 6.5 6.0 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein YihI PF04220.7 OAJ05623.1 - 2.8 7.2 9.2 4.7 6.5 6.4 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) YscO PF07321.7 OAJ05623.1 - 8.8 6.1 9.4 0.34 10.7 0.1 3.0 3 1 0 3 3 3 0 Type III secretion protein YscO WD40 PF00400.27 OAJ05624.1 - 1.3e-16 59.7 15.3 0.00018 21.2 0.0 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ05624.1 - 0.011 14.4 0.0 0.11 11.1 0.0 2.4 2 2 1 4 4 4 0 Nup133 N terminal like COG4 PF08318.7 OAJ05625.1 - 3.2e-40 137.9 0.0 6.7e-24 84.2 0.0 2.4 2 0 0 2 2 2 2 COG4 transport protein Dor1 PF04124.7 OAJ05625.1 - 0.1 11.0 0.1 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family Ras PF00071.17 OAJ05626.1 - 4.3e-65 218.0 0.8 5e-65 217.8 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ05626.1 - 7e-21 74.9 0.0 9.9e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ05626.1 - 9.1e-18 64.1 0.1 1.2e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ05626.1 - 1.1e-06 27.9 0.1 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ05626.1 - 3.9e-06 26.4 0.2 7.4e-06 25.5 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ05626.1 - 4.3e-05 23.4 0.1 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ05626.1 - 5.1e-05 22.5 0.1 6.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 OAJ05626.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 OAJ05626.1 - 0.0032 16.7 0.1 0.027 13.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 OAJ05626.1 - 0.011 15.9 0.1 0.61 10.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ05626.1 - 0.016 15.2 0.2 0.1 12.5 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 OAJ05626.1 - 0.018 14.2 0.1 0.066 12.4 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ05626.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 OAJ05626.1 - 0.036 13.7 0.0 0.089 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 OAJ05626.1 - 0.073 12.5 0.0 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Herpes_gE PF02480.11 OAJ05627.1 - 0.035 12.3 0.0 0.066 11.4 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 OAJ05627.1 - 0.076 12.8 0.3 0.076 12.8 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Herpes_UL25 PF01499.11 OAJ05627.1 - 0.083 11.1 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family SDA1 PF05285.7 OAJ05628.1 - 0.92 8.7 16.8 0.12 11.6 4.9 2.3 2 0 0 2 2 2 0 SDA1 Ebola_NP PF05505.7 OAJ05628.1 - 6.1 4.7 12.9 13 3.7 8.9 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein Pdase_C33_assoc PF14756.1 OAJ05629.1 - 0.095 12.4 0.0 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase_C33-associated domain TAF8_C PF10406.4 OAJ05630.1 - 8.4e-07 28.9 2.8 8.4e-07 28.9 1.9 2.6 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term SpoVAE PF14097.1 OAJ05631.1 - 0.029 13.7 1.5 0.043 13.2 0.2 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AE1 Cep57_CLD_2 PF14197.1 OAJ05631.1 - 0.04 13.8 13.3 0.096 12.6 5.7 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Filament PF00038.16 OAJ05631.1 - 0.04 13.3 21.9 0.23 10.8 0.2 3.1 2 1 1 3 3 3 0 Intermediate filament protein COG5 PF10392.4 OAJ05631.1 - 0.23 11.4 4.6 6.5 6.7 0.8 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 OAJ05631.1 - 0.48 10.2 4.7 0.54 10.0 1.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.7 OAJ05631.1 - 0.49 8.5 4.7 1.9 6.5 1.2 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 OAJ05631.1 - 1.3 8.8 16.4 0.78 9.6 1.3 3.5 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 OAJ05631.1 - 4.8 5.5 11.6 0.042 12.3 1.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF812) COG2 PF06148.6 OAJ05631.1 - 7.5 6.4 8.6 1.4 8.8 0.8 2.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 OAJ05631.1 - 7.7 6.0 18.5 0.73 9.4 4.2 3.1 2 1 1 3 3 3 0 IncA protein Spc7 PF08317.6 OAJ05631.1 - 7.8 5.0 10.6 0.21 10.2 1.0 2.3 3 0 0 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 OAJ05631.1 - 9.8 6.0 14.2 0.077 12.8 2.7 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding K_oxygenase PF13434.1 OAJ05632.1 - 6.2e-06 25.3 0.0 0.0044 15.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 OAJ05632.1 - 0.0021 18.1 0.1 14 5.6 0.0 3.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ05632.1 - 0.0096 15.7 0.8 0.11 12.2 0.1 2.9 2 1 1 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 OAJ05632.1 - 1 9.4 2.9 7.6 6.6 0.0 3.0 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain COPR5 PF15340.1 OAJ05633.1 - 0.054 13.8 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Cooperator of PRMT5 family HLH PF00010.21 OAJ05634.1 - 1e-13 50.7 0.0 3.8e-13 48.9 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.27 OAJ05635.1 - 0.0012 18.6 3.5 0.007 16.2 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Ion_trans PF00520.26 OAJ05636.1 - 8e-106 351.6 83.2 5.3e-35 120.4 7.2 5.0 5 0 0 5 5 5 4 Ion transport protein DUF1492 PF07374.6 OAJ05636.1 - 1.1 9.4 2.1 1.6 8.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Mito_carr PF00153.22 OAJ05643.1 - 3.9e-12 45.7 0.1 6.9e-07 28.8 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein zf-CCCH PF00642.19 OAJ05645.1 - 6.9e-13 47.9 14.6 8.3e-07 28.5 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 OAJ05645.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 OAJ05645.1 - 0.26 11.2 2.8 6.1 6.8 0.2 2.5 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Proteasome PF00227.21 OAJ05646.1 - 1.7e-58 197.0 0.1 2.2e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 OAJ05646.1 - 2.3e-15 55.5 0.4 5.8e-15 54.2 0.3 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CBFD_NFYB_HMF PF00808.18 OAJ05647.1 - 2e-15 56.5 0.0 4.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ05647.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF3753 PF12575.3 OAJ05647.1 - 0.069 12.9 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Toxin_63 PF15541.1 OAJ05647.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 63 Nup88 PF10168.4 OAJ05647.1 - 0.39 8.5 2.4 1.1 7.0 1.3 1.7 1 1 1 2 2 2 0 Nuclear pore component Spc24 PF08286.6 OAJ05648.1 - 9.4e-09 34.9 0.2 2.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF2216 PF10226.4 OAJ05648.1 - 0.007 15.8 0.3 0.0085 15.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) MscS_porin PF12795.2 OAJ05648.1 - 0.0075 15.6 1.0 0.012 14.9 0.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Herpes_UL6 PF01763.11 OAJ05648.1 - 0.033 12.3 0.2 0.042 12.0 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF342 PF03961.8 OAJ05648.1 - 0.053 11.9 0.3 0.067 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med21 PF11221.3 OAJ05648.1 - 0.12 12.2 4.2 3.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Muted PF14942.1 OAJ05648.1 - 0.17 11.7 5.2 0.28 11.0 3.6 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein TMF_DNA_bd PF12329.3 OAJ05648.1 - 0.32 10.8 6.4 0.79 9.5 1.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TBPIP PF07106.8 OAJ05648.1 - 0.86 9.1 4.0 1.3 8.5 2.4 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 OAJ05648.1 - 1.3 8.6 7.3 7.3 6.2 5.0 2.0 1 1 0 1 1 1 0 Mnd1 family Tropomyosin_1 PF12718.2 OAJ05648.1 - 2 8.2 10.8 13 5.6 0.2 2.2 1 1 0 2 2 2 0 Tropomyosin like Med9 PF07544.8 OAJ05648.1 - 2 8.1 8.1 48 3.7 0.0 2.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HR1 PF02185.11 OAJ05648.1 - 5 6.9 6.9 9.4 6.0 0.2 2.7 2 1 0 2 2 2 0 Hr1 repeat DUF4164 PF13747.1 OAJ05648.1 - 6.8 6.8 10.3 8.2 6.6 5.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ox_reductase_C PF08635.5 OAJ05649.1 - 2e-77 257.4 0.1 3.2e-77 256.7 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 OAJ05649.1 - 8.5e-24 84.3 0.0 1.9e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RNA_pol_L_2 PF13656.1 OAJ05650.1 - 5.4e-27 93.0 0.0 7.9e-27 92.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 OAJ05650.1 - 7.2e-08 31.4 0.0 9.6e-08 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.1 OAJ05650.1 - 0.11 10.2 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase zf-C2H2 PF00096.21 OAJ05650.1 - 0.12 12.7 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type ARGLU PF15346.1 OAJ05651.1 - 0.046 13.4 7.4 0.12 12.1 5.2 1.6 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 ThuA PF06283.6 OAJ05652.1 - 4.7e-56 189.9 1.2 1.4e-44 152.3 0.3 2.1 2 0 0 2 2 2 2 Trehalose utilisation Serglycin PF04360.7 OAJ05652.1 - 1.8 8.2 8.4 3.9 7.2 5.8 1.5 1 0 0 1 1 1 0 Serglycin Sen15 PF09631.5 OAJ05653.1 - 3.8e-12 46.3 0.0 1.7e-11 44.2 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein DUF2392 PF10288.4 OAJ05654.1 - 4.1e-14 52.8 0.0 6.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) APS_kinase PF01583.15 OAJ05655.1 - 5e-70 234.1 0.0 6e-70 233.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 OAJ05655.1 - 6e-08 32.6 0.0 7.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ05655.1 - 7.4e-06 26.7 0.0 1e-05 26.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ05655.1 - 0.0001 22.5 0.0 0.0002 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ05655.1 - 0.0006 19.0 0.0 0.00097 18.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 OAJ05655.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.16 OAJ05655.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Zeta_toxin PF06414.7 OAJ05655.1 - 0.071 12.1 0.0 0.16 11.0 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin PRK PF00485.13 OAJ05655.1 - 0.093 12.2 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 OAJ05655.1 - 0.094 12.6 0.1 0.2 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 OAJ05655.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribosomal_L1 PF00687.16 OAJ05656.1 - 2.5e-50 170.8 1.1 2.9e-50 170.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Borealin PF10512.4 OAJ05656.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Ribosomal_L10 PF00466.15 OAJ05657.1 - 4.3e-15 55.4 0.0 6.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 PBP1_TM PF14812.1 OAJ05657.1 - 0.059 13.6 10.1 0.13 12.5 7.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MSP1_C PF07462.6 OAJ05657.1 - 0.09 11.1 3.5 0.11 10.8 2.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NOA36 PF06524.7 OAJ05657.1 - 0.65 9.1 10.8 0.96 8.6 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 OAJ05657.1 - 0.95 7.8 9.1 1.4 7.3 6.3 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 OAJ05657.1 - 0.98 9.6 15.1 0.84 9.9 9.4 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 OAJ05657.1 - 1.6 8.2 10.1 2.9 7.4 7.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 OAJ05657.1 - 2.6 7.0 8.8 4.3 6.3 6.1 1.3 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.7 OAJ05657.1 - 7.5 6.1 9.7 12 5.4 6.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MIP PF00230.15 OAJ05659.1 - 8.3e-39 133.3 11.8 1.1e-38 132.9 8.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein PTPS_related PF10131.4 OAJ05659.1 - 0.017 13.2 0.2 0.017 13.2 0.1 1.5 2 0 0 2 2 2 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Polysacc_deac_1 PF01522.16 OAJ05660.1 - 2.6e-23 81.9 0.0 4.6e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.4 OAJ05660.1 - 0.00026 20.3 4.2 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Virulence protein nec1 Polysacc_deac_1 PF01522.16 OAJ05661.1 - 4.4e-26 90.9 0.1 1.5e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.6 OAJ05661.1 - 0.15 9.9 11.5 0.18 9.6 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DASH_Spc34 PF08657.5 OAJ05662.1 - 2.5e-09 37.2 3.1 5.4e-07 29.5 2.0 2.5 1 1 0 1 1 1 1 DASH complex subunit Spc34 PhyH PF05721.8 OAJ05662.1 - 0.031 14.3 0.3 0.083 12.9 0.1 1.8 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Chs3p PF12271.3 OAJ05663.1 - 3.7e-31 108.2 13.9 1.8e-30 105.9 7.7 2.0 2 0 0 2 2 2 2 Chitin synthase III catalytic subunit 2TM PF13239.1 OAJ05663.1 - 8.2 6.5 7.7 4 7.5 1.4 2.9 2 0 0 2 2 2 0 2TM domain UPF0020 PF01170.13 OAJ05665.1 - 2.8e-16 59.6 0.0 2.1e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 OAJ05665.1 - 1.8e-14 53.7 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ05665.1 - 0.00042 19.9 0.0 0.0065 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Vault PF01505.13 OAJ05665.1 - 0.003 17.5 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 Major Vault Protein repeat Methyltransf_25 PF13649.1 OAJ05665.1 - 0.004 17.4 0.0 0.014 15.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05665.1 - 0.02 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ05665.1 - 0.07 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 OAJ05665.1 - 0.085 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain N6_Mtase PF02384.11 OAJ05665.1 - 0.092 11.8 0.0 0.17 10.9 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase N2227 PF07942.7 OAJ05665.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein TP_methylase PF00590.15 OAJ05666.1 - 2.6e-34 118.7 0.2 5.3e-34 117.7 0.1 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 OAJ05666.1 - 1.3e-08 35.0 0.0 5.4e-07 29.8 0.0 2.7 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 OAJ05666.1 - 4.1e-07 28.8 0.1 1e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 OAJ05666.1 - 2.5e-06 26.7 0.0 0.0021 17.3 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CAP_N PF01213.14 OAJ05666.1 - 3.4 6.8 6.5 8.4 5.5 4.5 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Adaptin_binding PF10199.4 OAJ05667.1 - 0.0011 19.2 2.5 0.0011 19.2 1.7 3.2 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 MBOAT PF03062.14 OAJ05668.1 - 8.8e-42 143.3 0.0 4.5e-41 141.0 0.0 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RNase_T PF00929.19 OAJ05669.1 - 2.3e-07 31.2 0.0 6.8e-06 26.4 0.0 2.6 3 0 0 3 3 3 1 Exonuclease Nop14 PF04147.7 OAJ05669.1 - 0.00038 18.5 7.9 0.00038 18.5 5.5 2.8 3 0 0 3 3 3 2 Nop14-like family JAB PF01398.16 OAJ05670.1 - 5.1e-07 29.4 0.0 2.9e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF883 PF05957.8 OAJ05670.1 - 0.064 13.6 4.9 0.35 11.2 0.5 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Complex1_LYR PF05347.10 OAJ05671.1 - 2.5e-05 23.9 0.7 4.4e-05 23.1 0.5 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ05671.1 - 0.00061 19.9 0.9 0.0012 18.9 0.6 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAJ05671.1 - 0.071 13.5 0.3 0.1 13.1 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DEAD PF00270.24 OAJ05672.1 - 4.8e-24 84.7 0.0 8.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 OAJ05672.1 - 2.5e-13 50.4 2.0 9.6e-13 48.5 0.8 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 OAJ05672.1 - 3.6e-11 42.7 0.0 1.3e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 OAJ05672.1 - 1.8e-05 24.7 0.0 4.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 DNA replication factor CDT1 like Ribosomal_S4e PF00900.15 OAJ05672.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal family S4e Methyltransf_16 PF10294.4 OAJ05673.1 - 3.7e-14 52.5 0.0 7.1e-06 25.5 0.0 2.3 2 1 0 2 2 2 2 Putative methyltransferase Phage_min_tail PF05939.8 OAJ05673.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage minor tail protein NOC3p PF07540.6 OAJ05674.1 - 1e-22 80.2 0.9 3.1e-18 65.8 0.0 3.1 3 0 0 3 3 3 2 Nucleolar complex-associated protein CBF PF03914.12 OAJ05674.1 - 1.4e-17 63.6 0.0 1.4e-17 63.6 0.0 4.1 3 3 1 4 4 4 1 CBF/Mak21 family 60KD_IMP PF02096.15 OAJ05674.1 - 0.82 9.2 1.0 1.5 8.4 0.7 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein IF4E PF01652.13 OAJ05675.1 - 1.6e-43 148.0 0.0 3.6e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E ATP_synt_H PF05493.8 OAJ05676.1 - 5.2e-22 77.6 4.1 6.2e-22 77.4 2.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Claudin_2 PF13903.1 OAJ05676.1 - 0.02 14.5 6.1 0.025 14.2 4.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 OAJ05676.1 - 0.17 11.3 2.4 0.16 11.3 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ABC2_membrane_5 PF13346.1 OAJ05676.1 - 0.17 11.1 3.4 0.19 10.9 2.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1628 PF07790.6 OAJ05676.1 - 0.18 12.5 0.8 0.24 12.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) NfeD PF01957.13 OAJ05676.1 - 0.45 10.6 2.5 0.47 10.5 1.7 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 OAJ05676.1 - 0.77 8.4 7.2 0.83 8.2 5.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1345 PF07077.6 OAJ05676.1 - 0.77 9.2 2.9 0.94 8.9 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) RDD PF06271.7 OAJ05676.1 - 2 8.3 4.9 3.6 7.4 3.5 1.3 1 1 0 1 1 1 0 RDD family OppC_N PF12911.2 OAJ05676.1 - 2 7.8 4.5 3.5 7.0 1.0 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_2 PF12679.2 OAJ05676.1 - 5.3 5.8 6.5 5.8 5.6 4.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein RVT_1 PF00078.22 OAJ05677.1 - 1.1e-17 64.1 0.0 4.2e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DASH_Dam1 PF08653.5 OAJ05678.1 - 1.8e-21 75.6 0.8 3.1e-21 74.8 0.3 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 NAD_binding_10 PF13460.1 OAJ05679.1 - 0.097 12.6 0.3 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding F-box-like PF12937.2 OAJ05680.1 - 3.2e-13 49.1 1.9 1.1e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ05680.1 - 6.7e-08 31.9 0.1 3.8e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain PQQ PF01011.16 OAJ05680.1 - 4.1e-05 22.9 0.2 0.16 11.5 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 OAJ05680.1 - 0.00094 18.6 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain F-box-like PF12937.2 OAJ05681.1 - 1.6e-10 40.5 0.2 1.6e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ05681.1 - 9.2e-06 25.1 1.2 2.3e-05 23.8 0.1 2.2 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 OAJ05681.1 - 0.1 12.0 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 PQQ-like domain AARP2CN PF08142.7 OAJ05681.1 - 0.15 11.6 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 AARP2CN (NUC121) domain Phage_integrase PF00589.17 OAJ05684.1 - 7.2e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ05684.1 - 0.025 14.7 0.7 0.06 13.5 0.1 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain XPG_I PF00867.13 OAJ05685.1 - 5.1e-16 58.5 0.0 2.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 OAJ05685.1 - 2.5e-06 27.6 0.0 7.8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain DUF1308 PF07000.6 OAJ05686.1 - 2.4e-24 85.6 0.1 2.4e-11 42.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) RBD PF02196.10 OAJ05686.1 - 0.087 12.5 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain Glycos_transf_1 PF00534.15 OAJ05687.1 - 9.6e-29 99.9 0.0 1.7e-27 95.9 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 OAJ05687.1 - 3.3e-14 53.3 0.0 9.3e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 OAJ05687.1 - 2.9e-12 46.6 0.0 5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 OAJ05687.1 - 3.1e-12 46.8 0.0 7.6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 OAJ05687.1 - 0.0079 16.4 5.1 0.68 10.2 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferases group 1 Helicase_C PF00271.26 OAJ05688.1 - 8.6e-12 44.7 0.0 2.6e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ05688.1 - 3.5e-07 29.8 0.0 1.5e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Glyco_transf_17 PF04724.8 OAJ05690.1 - 8e-88 294.8 0.0 1.1e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 E1-E2_ATPase PF00122.15 OAJ05691.1 - 8.7e-59 198.3 0.2 8.7e-59 198.3 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 OAJ05691.1 - 6.1e-43 146.4 2.7 6.1e-43 146.4 1.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 OAJ05691.1 - 6.5e-26 92.0 0.0 4.1e-25 89.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ05691.1 - 2.5e-19 69.0 0.1 5.2e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 OAJ05691.1 - 5.6e-16 59.2 0.0 1.4e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 OAJ05691.1 - 1.2e-09 37.4 0.1 4.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 OAJ05691.1 - 6.9e-05 22.5 0.3 0.013 15.1 0.2 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.16 OAJ05692.1 - 7.5e-17 61.1 0.0 1.6e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 OAJ05692.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 LCCL PF03815.14 OAJ05693.1 - 8.7e-14 51.2 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Ribosomal_S19e PF01090.14 OAJ05703.1 - 2e-52 176.3 0.0 2.4e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e SDA1 PF05285.7 OAJ05703.1 - 0.3 10.3 7.6 0.38 9.9 5.3 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.3 OAJ05703.1 - 0.42 10.5 11.6 0.54 10.1 8.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 OAJ05703.1 - 0.43 10.2 8.3 0.51 10.0 5.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.6 OAJ05703.1 - 0.44 10.3 5.0 0.59 9.9 3.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Bd3614_N PF14442.1 OAJ05703.1 - 0.82 9.6 5.8 1.2 9.1 4.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal NOA36 PF06524.7 OAJ05703.1 - 3 7.0 9.0 3.4 6.8 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 OAJ05703.1 - 6.8 4.5 7.4 8.1 4.3 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ05703.1 - 7.4 6.1 13.8 10 5.7 9.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region GPP34 PF05719.6 OAJ05704.1 - 7.3e-63 212.3 0.0 1.2e-62 211.6 0.0 1.4 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M24 PF00557.19 OAJ05705.1 - 5.8e-20 71.7 0.0 7.4e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SMC_N PF02463.14 OAJ05706.1 - 3.4e-61 206.2 0.0 1.5e-60 204.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 OAJ05706.1 - 3.2e-28 98.1 2.6 1.2e-27 96.3 0.1 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 OAJ05706.1 - 8.2e-17 62.0 1.1 1.2e-07 32.0 0.0 4.0 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 OAJ05706.1 - 2.6e-08 33.2 0.2 1.2e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 OAJ05706.1 - 5.9e-05 22.2 0.0 0.00071 18.7 0.0 5.0 5 1 0 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 OAJ05706.1 - 0.00017 21.4 0.7 0.0021 17.9 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 OAJ05706.1 - 0.0023 17.2 25.8 0.42 9.7 2.7 4.6 3 2 2 5 5 5 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ05706.1 - 0.063 13.5 0.0 0.063 13.5 0.0 6.2 4 3 0 4 4 4 0 ABC transporter AAA_23 PF13476.1 OAJ05706.1 - 1.2 9.3 106.6 0.082 13.2 32.1 6.7 2 2 1 3 3 3 0 AAA domain Ribosomal_L18e PF00828.14 OAJ05707.1 - 3e-34 118.1 0.4 3.9e-34 117.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Rhodanese PF00581.15 OAJ05708.1 - 5.4e-17 62.1 0.0 1.7e-09 38.0 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain GTP_EFTU PF00009.22 OAJ05709.1 - 2.5e-45 154.2 0.0 4.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 OAJ05709.1 - 1.5e-09 37.8 0.5 7.6e-09 35.5 0.7 1.9 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 OAJ05709.1 - 1e-08 35.2 0.0 2.8e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ05709.1 - 3e-07 30.4 0.6 6.9e-07 29.2 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ05709.1 - 7.5e-07 29.1 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 OAJ05709.1 - 2.6e-06 26.9 0.3 6e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 OAJ05709.1 - 0.0036 16.5 0.0 0.51 9.5 0.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 OAJ05709.1 - 0.0082 16.6 0.0 0.033 14.7 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 OAJ05709.1 - 0.092 12.4 0.1 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 OAJ05709.1 - 0.11 12.3 0.0 1.5 8.6 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 OAJ05709.1 - 0.13 11.2 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin RNA_pol_Rbc25 PF08292.7 OAJ05711.1 - 3.2e-27 95.1 0.0 2e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 OAJ05711.1 - 1.2e-15 57.4 0.0 1.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 OAJ05711.1 - 0.004 17.2 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain UQ_con PF00179.21 OAJ05712.1 - 7.2e-16 57.8 0.0 7.7e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 OAJ05712.1 - 0.0015 18.4 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Ribonuc_P_40 PF08584.6 OAJ05713.1 - 4.6e-36 124.2 0.0 1e-21 77.2 0.0 2.6 2 1 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit Nop14 PF04147.7 OAJ05713.1 - 0.14 10.0 14.2 0.21 9.4 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 OAJ05713.1 - 6.5 4.6 19.6 9.8 4.0 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 OAJ05713.1 - 8.8 5.8 9.3 15 5.1 6.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C2H2_4 PF13894.1 OAJ05714.1 - 4.7e-05 23.4 7.9 0.19 12.1 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 OAJ05714.1 - 0.0015 18.7 13.8 0.74 10.2 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type TPR_11 PF13414.1 OAJ05715.1 - 4.1e-11 42.3 14.3 7.1e-05 22.3 0.0 8.3 7 2 1 9 9 9 4 TPR repeat TPR_1 PF00515.23 OAJ05715.1 - 1.4e-08 33.9 15.9 0.24 11.0 0.0 8.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ05715.1 - 2.2e-07 30.5 0.8 11 6.4 0.1 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05715.1 - 2.6e-07 30.0 21.7 0.17 11.8 0.0 9.4 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ05715.1 - 6.7e-05 22.7 0.0 6.7e-05 22.7 0.0 7.9 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05715.1 - 0.00022 20.7 7.4 6.6 6.7 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ05715.1 - 0.00033 20.9 31.8 0.78 10.1 0.0 8.7 8 1 1 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ05715.1 - 0.0018 18.3 0.4 0.19 11.9 0.0 4.4 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ05715.1 - 0.035 14.7 0.2 0.035 14.7 0.1 12.4 13 1 1 14 14 14 0 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05715.1 - 1.2 9.8 0.0 1.2 9.8 0.0 9.5 9 2 2 11 11 11 0 Tetratricopeptide repeat RVT_2 PF07727.9 OAJ05716.1 - 8.8e-82 273.7 0.0 1.2e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 OAJ05716.1 - 3e-07 29.9 0.4 8.5e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 OAJ05716.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.21 OAJ05716.1 - 0.00038 20.5 0.0 0.00094 19.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain POP1 PF06978.6 OAJ05717.1 - 8.4e-34 116.8 21.6 4.5e-33 114.4 10.2 2.6 2 0 0 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 OAJ05717.1 - 1.1e-12 47.6 0.4 1.1e-12 47.6 0.3 2.6 2 1 0 2 2 2 1 POPLD (NUC188) domain Nop14 PF04147.7 OAJ05717.1 - 0.12 10.2 14.1 0.19 9.6 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family RNase_H2-Ydr279 PF09468.5 OAJ05717.1 - 0.69 9.0 10.2 1.6 7.8 7.0 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 OAJ05717.1 - 2 6.3 12.8 3 5.7 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NADH-u_ox-rdase PF10785.4 OAJ05718.1 - 1e-32 112.2 0.1 1.3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 OAJ05718.1 - 1.5e-11 43.8 0.0 2.4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit efThoc1 PF11957.3 OAJ05719.1 - 1.1e-62 212.2 4.6 8.7e-33 113.5 0.0 4.3 3 1 0 3 3 3 3 THO complex subunit 1 transcription elongation factor RRM_1 PF00076.17 OAJ05720.1 - 1.3e-15 56.7 0.1 2.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05720.1 - 1.4e-12 47.3 0.0 2.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05720.1 - 3.2e-07 30.0 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ05720.1 - 0.0058 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif ubiquitin PF00240.18 OAJ05721.1 - 2.9e-33 113.0 0.7 2.9e-33 113.0 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 OAJ05721.1 - 1.8e-26 91.7 1.0 3.6e-26 90.7 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 OAJ05721.1 - 6.8e-19 67.3 0.5 1.2e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 OAJ05721.1 - 1.2e-05 25.4 0.3 0.00025 21.2 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 OAJ05721.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 OAJ05721.1 - 0.0011 18.8 0.4 0.002 17.9 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 OAJ05721.1 - 0.011 15.5 0.9 0.018 14.9 0.7 1.4 1 0 0 1 1 1 0 IBR domain DUF2407 PF10302.4 OAJ05721.1 - 0.013 15.6 0.5 0.017 15.2 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 OAJ05721.1 - 0.043 13.8 0.8 0.096 12.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 OAJ05721.1 - 0.28 9.4 2.8 0.71 8.1 0.1 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain AIRC PF00731.15 OAJ05722.1 - 3.3e-58 195.2 1.3 8.6e-58 193.8 0.9 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 OAJ05722.1 - 1.1e-51 174.5 0.1 2.3e-28 98.7 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain ATP-grasp_4 PF13535.1 OAJ05722.1 - 1.5e-08 34.6 0.2 4.9e-08 32.9 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 OAJ05722.1 - 0.00099 18.2 0.2 0.0043 16.2 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 OAJ05722.1 - 0.0069 15.7 0.0 0.016 14.5 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.13 OAJ05722.1 - 0.022 14.4 2.6 0.038 13.6 0.0 2.6 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M35 PF02102.10 OAJ05722.1 - 0.33 9.5 3.7 0.71 8.4 2.6 1.4 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Pkinase PF00069.20 OAJ05723.1 - 1.5e-31 109.4 0.0 1.6e-24 86.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05723.1 - 1e-12 47.7 0.0 5.6e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ05723.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Nucleoplasmin PF03066.10 OAJ05723.1 - 0.15 11.5 9.5 0.26 10.7 0.3 2.4 2 0 0 2 2 2 0 Nucleoplasmin ECH PF00378.15 OAJ05724.1 - 6.6e-75 251.3 1.4 8.7e-75 250.9 1.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 OAJ05724.1 - 0.00024 20.9 0.5 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 Porphobil_deam PF01379.15 OAJ05725.1 - 3.3e-68 228.8 0.0 4.6e-64 215.2 0.0 2.2 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 OAJ05725.1 - 8.2e-15 54.6 0.0 1.8e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain GTP_EFTU PF00009.22 OAJ05726.1 - 1.3e-32 112.7 0.1 1.6e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RVT_1 PF00078.22 OAJ05728.1 - 0.00052 19.4 0.0 0.0025 17.2 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.17 OAJ05729.1 - 0.00012 21.8 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ05729.1 - 0.0019 18.3 0.1 0.011 15.9 0.0 2.3 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain DUF2205 PF10224.4 OAJ05730.1 - 5.9e-15 54.5 0.0 7.6e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 OAJ05730.1 - 0.00036 20.8 0.1 0.00044 20.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Cast PF10174.4 OAJ05730.1 - 0.032 12.3 0.1 0.038 12.0 0.1 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Dynamitin PF04912.9 OAJ05730.1 - 0.041 12.6 0.7 0.049 12.4 0.5 1.0 1 0 0 1 1 1 0 Dynamitin Reo_sigmaC PF04582.7 OAJ05730.1 - 0.068 12.3 0.4 0.074 12.2 0.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Hamartin PF04388.7 OAJ05731.1 - 0.16 10.6 2.8 0.24 10.0 1.9 1.3 1 0 0 1 1 1 0 Hamartin protein Metallophos PF00149.23 OAJ05733.1 - 1.3e-40 138.9 0.9 1.8e-40 138.4 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4653 PF15546.1 OAJ05733.1 - 1.2 8.3 10.7 0.69 9.1 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) ParA PF10609.4 OAJ05734.1 - 5.4e-26 90.2 0.0 9.5e-26 89.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 OAJ05734.1 - 2.2e-15 56.5 0.6 1.2e-14 54.2 0.4 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ05734.1 - 1.7e-07 31.3 0.1 5.1e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.1 OAJ05734.1 - 0.00018 21.1 0.1 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ05734.1 - 0.00061 19.4 2.1 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain MipZ PF09140.6 OAJ05734.1 - 0.00068 18.7 0.1 0.0043 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 OAJ05734.1 - 0.00073 18.9 0.1 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 OAJ05734.1 - 0.02 13.9 0.5 0.21 10.6 0.1 2.3 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.13 OAJ05734.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family UBN2 PF14223.1 OAJ05736.1 - 2.8e-10 39.9 1.1 5.1e-09 35.9 0.1 2.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ05736.1 - 8.1e-05 22.1 0.0 0.00027 20.5 0.0 1.9 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MAAL_C PF07476.6 OAJ05736.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Retrotrans_gag PF03732.12 OAJ05736.1 - 0.033 14.2 2.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 0 Retrotransposon gag protein MADF_DNA_bdg PF10545.4 OAJ05736.1 - 0.09 12.9 0.0 0.32 11.2 0.0 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like UBN2_3 PF14244.1 OAJ05736.1 - 0.13 11.7 1.1 0.52 9.8 0.1 2.4 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Reprolysin_3 PF13582.1 OAJ05736.1 - 0.35 11.3 1.8 30 5.1 0.0 3.0 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like RVT_2 PF07727.9 OAJ05737.1 - 1.4e-75 253.4 0.0 2.2e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ05737.1 - 4.2e-17 62.3 0.0 8e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UBN2_2 PF14227.1 OAJ05737.1 - 1.5e-11 43.8 0.0 2.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 OAJ05737.1 - 2.2e-08 33.9 0.0 3.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 OAJ05737.1 - 4e-05 23.1 0.0 0.00011 21.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 OAJ05737.1 - 0.0042 16.9 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF4219 PF13961.1 OAJ05737.1 - 0.005 16.2 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 OAJ05737.1 - 0.037 13.9 7.0 0.085 12.8 4.9 1.7 1 0 0 1 1 1 0 Zinc knuckle rve_3 PF13683.1 OAJ05737.1 - 0.073 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_3 PF13917.1 OAJ05737.1 - 0.47 10.2 2.9 1.5 8.5 2.0 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ05737.1 - 0.75 9.3 4.6 1.5 8.3 3.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_3 PF13456.1 OAJ05738.1 - 0.0038 16.9 0.3 0.0084 15.8 0.0 1.8 2 1 0 2 2 2 1 Reverse transcriptase-like Abhydrolase_3 PF07859.8 OAJ05739.1 - 2.2e-23 82.9 0.0 2.8e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ05739.1 - 4.8e-08 32.8 0.0 6.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 OAJ05739.1 - 0.00022 21.2 1.5 0.00043 20.2 1.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 OAJ05739.1 - 0.00035 20.3 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase DLH PF01738.13 OAJ05739.1 - 0.002 17.4 0.0 0.13 11.5 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 OAJ05739.1 - 0.016 14.4 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Smr PF01713.16 OAJ05742.1 - 2.8e-10 40.2 0.0 2.9e-09 36.9 0.0 2.8 3 1 0 3 3 3 1 Smr domain Nucleoplasmin PF03066.10 OAJ05742.1 - 2.3 7.7 9.5 5.3 6.5 6.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin CsbD PF05532.7 OAJ05743.1 - 0.026 14.2 1.3 0.046 13.4 0.9 1.4 1 0 0 1 1 1 0 CsbD-like Arginosuc_synth PF00764.14 OAJ05744.1 - 5.2e-155 516.2 0.0 5.9e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 OAJ05744.1 - 0.00015 21.1 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 OAJ05744.1 - 0.0019 17.7 0.0 0.0063 16.0 0.0 1.8 2 0 0 2 2 2 1 Asparagine synthase LolA PF03548.10 OAJ05744.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA tRNA_Me_trans PF03054.11 OAJ05744.1 - 0.044 12.3 0.0 0.065 11.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Ribosomal_S7 PF00177.16 OAJ05745.1 - 3.5e-28 98.0 0.0 5.4e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HLH PF00010.21 OAJ05746.1 - 8.6e-15 54.1 0.2 1.5e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MIP PF00230.15 OAJ05747.1 - 1.6e-47 161.9 4.9 2.3e-47 161.3 3.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.1 OAJ05747.1 - 0.13 12.2 2.3 0.36 10.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) Ribosomal_S2 PF00318.15 OAJ05749.1 - 2.1e-44 151.2 0.0 5.6e-24 84.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Avl9 PF09794.4 OAJ05751.1 - 2.1e-129 431.3 0.0 2.6e-129 430.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 OAJ05751.1 - 2.4e-07 30.4 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 OAJ05751.1 - 9.8e-07 28.3 0.0 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.7 OAJ05751.1 - 0.00088 19.2 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF829 PF05705.9 OAJ05752.1 - 1.7e-27 96.6 0.2 2.4e-17 63.4 0.0 3.4 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) TFCD_C PF12612.3 OAJ05753.1 - 3.9e-29 101.4 0.2 1.4e-27 96.3 0.0 3.6 5 1 0 5 5 5 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.2 OAJ05753.1 - 0.0036 17.1 0.0 1.7 8.4 0.0 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 OAJ05753.1 - 0.005 16.8 0.0 0.005 16.8 0.0 8.4 10 0 0 10 10 10 1 HEAT repeat Adaptin_N PF01602.15 OAJ05753.1 - 0.0064 14.8 1.4 0.47 8.7 0.0 3.9 4 1 0 4 4 4 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ05753.1 - 0.015 15.6 0.1 0.49 10.8 0.0 3.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region B56 PF01603.15 OAJ05753.1 - 0.023 13.3 0.1 0.21 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) HEAT_EZ PF13513.1 OAJ05753.1 - 0.029 14.8 0.1 0.029 14.8 0.0 8.5 7 2 2 9 9 9 0 HEAT-like repeat FeoB_C PF07664.7 OAJ05753.1 - 0.046 13.1 0.5 0.28 10.6 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus Nefa_Nip30_N PF10187.4 OAJ05754.1 - 2.4e-26 91.8 8.9 4.3e-26 91.0 6.1 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3423 PF11903.3 OAJ05754.1 - 1.4 8.6 4.2 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3423) Aldedh PF00171.17 OAJ05763.1 - 2.1e-156 520.8 0.3 2.4e-156 520.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 OAJ05764.1 - 2.7e-73 246.3 0.0 3.3e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05764.1 - 1.3e-33 116.1 0.0 3.4e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ05764.1 - 0.0018 17.3 0.1 0.003 16.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ05764.1 - 0.0022 17.0 0.0 0.004 16.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ05764.1 - 0.064 12.9 0.1 0.24 11.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPT PF03151.11 OAJ05765.1 - 2e-33 115.2 9.1 2e-33 115.2 6.3 2.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 OAJ05765.1 - 5.7e-13 48.9 20.9 5.7e-06 26.3 5.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 OAJ05765.1 - 5.1e-08 32.1 14.7 1.6e-07 30.6 10.2 1.7 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 OAJ05765.1 - 0.048 13.8 16.8 0.35 11.1 2.6 2.7 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 OAJ05765.1 - 0.084 11.9 5.4 0.14 11.2 0.1 2.8 2 1 0 2 2 2 0 Nucleotide-sugar transporter DUF2627 PF11118.3 OAJ05765.1 - 0.87 9.7 5.6 2.9 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Multi_Drug_Res PF00893.14 OAJ05765.1 - 1.9 8.9 10.3 0.2 12.1 3.6 1.9 2 0 0 2 2 2 0 Small Multidrug Resistance protein A_deaminase PF00962.17 OAJ05766.1 - 1.8e-109 365.7 0.1 2.3e-109 365.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase 4HBT PF03061.17 OAJ05767.1 - 4.1e-08 33.2 0.1 7.6e-08 32.3 0.1 1.5 1 1 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 OAJ05767.1 - 0.00078 19.2 0.1 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PX PF00787.19 OAJ05768.1 - 6.4e-10 38.8 0.0 1.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 PX domain XS PF03468.9 OAJ05769.1 - 0.029 14.2 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 XS domain RhoGEF PF00621.15 OAJ05770.1 - 8.6e-13 48.5 0.0 8.9e-09 35.4 0.0 2.5 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.24 OAJ05770.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 PH domain RRM_6 PF14259.1 OAJ05771.1 - 2.1e-05 24.4 0.0 0.0014 18.5 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ05771.1 - 3.4e-05 23.3 0.0 0.024 14.2 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.5 OAJ05771.1 - 0.027 14.7 13.3 0.076 13.2 9.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3537 PF12056.3 OAJ05771.1 - 0.27 9.8 2.0 0.42 9.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Host_attach PF10116.4 OAJ05771.1 - 2.4 8.3 0.0 2.4 8.3 0.0 3.5 3 1 0 3 3 3 0 Protein required for attachment to host cells Nop14 PF04147.7 OAJ05771.1 - 3.1 5.5 33.9 0.016 13.1 10.3 2.1 2 0 0 2 2 2 0 Nop14-like family Complex1_LYR_1 PF13232.1 OAJ05772.1 - 2.2e-14 53.3 0.0 3.6e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 OAJ05772.1 - 2.8e-07 30.2 6.3 6.1e-07 29.1 4.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CAF-1_p60_C PF15512.1 OAJ05772.1 - 0.17 12.2 2.2 0.23 11.8 1.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal Ras PF00071.17 OAJ05773.1 - 1.4e-27 96.0 0.0 3.2e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 OAJ05773.1 - 7.4e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ05773.1 - 6.9e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ05773.1 - 0.00035 19.8 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Nucleoplasmin PF03066.10 OAJ05773.1 - 5.4 6.5 7.3 2.1 7.8 1.1 2.6 3 0 0 3 3 3 0 Nucleoplasmin UPF0052 PF01933.13 OAJ05774.1 - 4.6e-39 134.5 0.0 2.3e-25 89.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 DDE_3 PF13358.1 OAJ05777.1 - 5.9e-17 61.7 0.0 1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ05777.1 - 1.1e-07 31.2 0.0 7.8e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ05777.1 - 5.5e-07 30.2 0.1 0.00021 22.0 0.0 2.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 OAJ05777.1 - 0.0031 17.6 0.0 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ05777.1 - 0.0033 17.4 0.4 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 OAJ05777.1 - 0.0038 16.8 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 OAJ05777.1 - 0.044 12.9 0.9 0.31 10.2 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_7 PF02796.10 OAJ05777.1 - 0.72 9.7 2.6 7.8 6.4 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase CaM_bdg_C0 PF10562.4 OAJ05781.1 - 0.024 14.4 0.0 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit F-box PF00646.28 OAJ05782.1 - 5e-08 32.4 1.5 1.7e-07 30.6 0.9 2.0 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 OAJ05782.1 - 0.0029 17.3 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 OAJ05782.1 - 0.0042 16.7 0.3 0.011 15.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like Acyl-thio_N PF12590.3 OAJ05783.1 - 1.8 9.0 7.4 0.07 13.5 0.9 1.7 3 0 0 3 3 3 0 Acyl-ATP thioesterase FXR1P_C PF12235.3 OAJ05783.1 - 5.8 6.9 6.0 1.2 9.1 2.1 1.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal SnoaL_2 PF12680.2 OAJ05784.1 - 4.6e-06 26.9 0.0 5.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 OAJ05784.1 - 0.00054 19.5 0.3 0.0013 18.2 0.2 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4448 PF14610.1 OAJ05785.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4064 PF13273.1 OAJ05786.1 - 0.086 12.9 1.7 1.6 8.8 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) MARVEL PF01284.18 OAJ05786.1 - 7.7 6.3 9.6 0.39 10.5 0.7 2.5 2 1 0 2 2 2 0 Membrane-associating domain HA2 PF04408.18 OAJ05787.1 - 3.8e-28 97.4 0.4 7.4e-28 96.5 0.3 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 OAJ05787.1 - 2e-24 85.6 0.0 3.7e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 OAJ05787.1 - 7.6e-11 41.7 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ05787.1 - 3.2e-06 27.2 0.0 8.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 OAJ05787.1 - 3.9e-06 26.4 0.0 8.9e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ05787.1 - 0.0099 15.7 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 OAJ05787.1 - 0.018 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 OAJ05787.1 - 0.021 14.2 0.1 0.077 12.4 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 OAJ05787.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 OAJ05787.1 - 0.048 12.7 0.0 0.15 11.1 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 OAJ05787.1 - 0.052 13.0 0.0 0.18 11.3 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ05787.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAJ05787.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter UPF0079 PF02367.12 OAJ05787.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PRELI PF04707.9 OAJ05788.1 - 6.1e-32 110.3 0.0 5.3e-24 84.5 0.1 2.0 2 0 0 2 2 2 2 PRELI-like family SufE PF02657.10 OAJ05788.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain zf-RING_2 PF13639.1 OAJ05790.1 - 1.4e-14 53.6 4.4 3e-14 52.5 3.1 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 OAJ05790.1 - 1.4e-09 37.5 0.0 1.2e-07 31.3 0.0 2.7 2 0 0 2 2 2 1 PA domain zf-C3HC4_2 PF13923.1 OAJ05790.1 - 2.6e-08 33.7 3.4 5.4e-08 32.7 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ05790.1 - 9e-06 25.3 2.1 1.7e-05 24.4 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 OAJ05790.1 - 1.5e-05 25.0 0.5 2.9e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ05790.1 - 3.4e-05 23.3 1.6 6.9e-05 22.4 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ05790.1 - 9.9e-05 21.9 5.7 0.00022 20.8 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ05790.1 - 0.028 14.2 1.9 0.058 13.2 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAJ05790.1 - 0.12 12.1 2.6 0.48 10.1 1.0 2.5 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 OAJ05790.1 - 0.23 10.9 0.7 0.45 10.0 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_6 PF13516.1 OAJ05792.1 - 1.6e-09 36.8 3.3 9.9 6.5 0.0 8.9 11 0 0 11 11 11 2 Leucine Rich repeat F-box-like PF12937.2 OAJ05792.1 - 1.1e-06 28.1 3.6 4.1e-06 26.4 1.6 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 OAJ05792.1 - 3.1e-06 26.6 0.0 4.9 6.8 0.0 5.2 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ05792.1 - 3.4e-06 26.7 2.3 0.31 10.8 0.0 4.5 5 0 0 5 5 5 2 Leucine rich repeat DUF1398 PF07166.6 OAJ05792.1 - 0.5 10.2 0.0 1.1 9.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) PBP1_TM PF14812.1 OAJ05792.1 - 0.65 10.3 8.6 1.7 9.0 1.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ05792.1 - 5.2 6.5 8.6 13 5.2 1.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin PP2C PF00481.16 OAJ05793.1 - 4.5e-27 95.0 0.0 2.2e-25 89.5 0.0 2.7 2 0 0 2 2 2 1 Protein phosphatase 2C Spt20 PF12090.3 OAJ05793.1 - 0.11 11.7 7.0 4.2 6.6 0.1 3.2 3 0 0 3 3 3 0 Spt20 family Ribosomal_60s PF00428.14 OAJ05793.1 - 4.7 7.6 9.2 0.45 10.9 0.3 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein AAA PF00004.24 OAJ05794.1 - 1.7e-22 80.0 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 OAJ05794.1 - 1.8e-06 27.5 0.1 7.4e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 OAJ05794.1 - 0.00081 19.4 1.6 0.024 14.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 OAJ05794.1 - 0.0032 17.0 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ05794.1 - 0.022 14.8 0.1 0.28 11.3 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ05794.1 - 0.09 12.5 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GST_C_3 PF14497.1 OAJ05795.1 - 4.8e-08 33.3 0.0 9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 OAJ05795.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ05795.1 - 0.00021 21.1 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADH_u_ox_C PF12853.2 OAJ05795.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit CNH PF00780.17 OAJ05796.1 - 0.98 8.7 0.0 31 3.8 0.0 2.1 2 0 0 2 2 2 0 CNH domain CRAL_TRIO PF00650.15 OAJ05797.1 - 5.4e-35 120.2 0.0 9.2e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ05797.1 - 3.4e-13 49.4 0.8 3.4e-13 49.4 0.6 2.6 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain ABC_tran PF00005.22 OAJ05798.1 - 8.7e-59 197.7 0.0 1e-28 100.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 OAJ05798.1 - 2.4e-58 197.7 25.9 7.2e-31 107.6 6.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 OAJ05798.1 - 7.1e-15 54.8 4.0 4.1e-07 29.4 1.3 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 OAJ05798.1 - 2.5e-09 36.5 0.0 0.00096 18.3 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 OAJ05798.1 - 2.2e-08 33.4 2.4 0.00047 19.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 OAJ05798.1 - 6e-08 32.9 0.0 0.9 9.4 0.0 4.7 3 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 OAJ05798.1 - 9.8e-08 32.8 0.1 0.0019 19.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ05798.1 - 6.4e-07 29.5 1.1 0.07 13.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 OAJ05798.1 - 1.4e-06 28.4 0.5 0.025 14.7 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 OAJ05798.1 - 3.2e-05 23.4 0.1 0.079 12.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 OAJ05798.1 - 3.2e-05 23.5 2.5 0.61 9.4 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 OAJ05798.1 - 4.6e-05 23.3 0.7 0.014 15.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.4 OAJ05798.1 - 0.00013 20.6 0.6 0.25 9.8 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 OAJ05798.1 - 0.00024 21.4 0.1 0.14 12.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 OAJ05798.1 - 0.00096 19.0 3.5 0.49 10.3 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 OAJ05798.1 - 0.0023 18.1 0.4 0.34 11.1 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAJ05798.1 - 0.0029 17.9 1.7 0.1 12.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 OAJ05798.1 - 0.0032 16.4 0.0 0.032 13.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 OAJ05798.1 - 0.0034 17.3 0.2 3.8 7.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 OAJ05798.1 - 0.0035 17.0 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 OAJ05798.1 - 0.0062 16.0 0.0 3.2 7.1 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 OAJ05798.1 - 0.016 15.0 1.1 0.26 11.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 IstB_IS21 PF01695.12 OAJ05798.1 - 0.032 13.6 0.1 1.8 7.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF3987 PF13148.1 OAJ05798.1 - 0.036 12.6 2.5 0.36 9.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RNA_helicase PF00910.17 OAJ05798.1 - 0.06 13.5 0.1 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 OAJ05798.1 - 0.069 12.9 0.3 15 5.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_14 PF13173.1 OAJ05798.1 - 0.07 13.0 0.0 0.52 10.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 OAJ05798.1 - 0.91 8.5 5.6 0.57 9.2 0.0 3.0 4 0 0 4 4 4 0 Zeta toxin Cu-oxidase_3 PF07732.10 OAJ05801.1 - 2.6e-39 133.5 5.6 1.3e-37 128.1 2.1 3.4 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 OAJ05801.1 - 1.7e-30 106.0 0.2 9.6e-29 100.3 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 OAJ05801.1 - 1.2e-28 99.2 8.9 2.1e-26 92.0 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase ETRAMP PF09716.5 OAJ05801.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) BAF1_ABF1 PF04684.8 OAJ05802.1 - 1.9 7.2 14.9 0.22 10.3 1.0 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 OAJ05803.1 - 0.2 11.0 5.3 0.22 10.8 3.7 1.1 1 0 0 1 1 1 0 Vta1 like Hist_deacetyl PF00850.14 OAJ05805.1 - 1.6e-78 264.1 0.1 2.5e-78 263.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Nop14 PF04147.7 OAJ05805.1 - 5 4.9 8.0 7.7 4.2 5.5 1.3 1 0 0 1 1 1 0 Nop14-like family Phosphoesterase PF04185.9 OAJ05808.1 - 5.2e-23 81.8 4.4 1.3e-22 80.5 3.1 1.5 1 1 0 1 1 1 1 Phosphoesterase family Vac14_Fig4_bd PF11916.3 OAJ05809.1 - 5.6e-75 250.4 6.5 1.4e-74 249.1 3.9 2.1 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 OAJ05809.1 - 1.2e-46 157.0 0.0 2e-41 140.2 0.0 4.1 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 OAJ05809.1 - 8.6e-18 62.7 2.9 4.9e-05 23.0 0.0 8.0 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 OAJ05809.1 - 4.1e-10 39.7 4.2 0.23 11.7 0.0 5.7 4 1 0 4 4 4 3 HEAT repeats ParcG PF10274.4 OAJ05809.1 - 6.1e-05 23.0 0.4 0.068 13.0 0.1 3.2 4 0 0 4 4 4 2 Parkin co-regulated protein HEAT_EZ PF13513.1 OAJ05809.1 - 0.0001 22.6 8.3 0.052 14.0 0.0 6.9 7 1 0 7 7 7 1 HEAT-like repeat Cnd1 PF12717.2 OAJ05809.1 - 0.00011 22.1 2.2 1 9.2 0.0 4.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 OAJ05809.1 - 0.0013 18.1 0.4 9.1 5.5 0.0 4.1 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 OAJ05809.1 - 0.047 13.5 1.9 6 6.8 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Dopey_N PF04118.9 OAJ05809.1 - 0.051 12.3 0.3 1.1 8.0 0.0 2.8 2 1 1 3 3 3 0 Dopey, N-terminal DUF2120 PF09893.4 OAJ05809.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) SAP18 PF06487.7 OAJ05811.1 - 5.6e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Clathrin_lg_ch PF01086.12 OAJ05812.1 - 5.3e-35 121.3 10.6 2.2e-32 112.8 4.2 2.4 1 1 0 2 2 2 2 Clathrin light chain DUF3729 PF12526.3 OAJ05812.1 - 10 7.5 9.4 1.9 9.8 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3729) UCH PF00443.24 OAJ05813.1 - 2.6e-49 167.7 0.0 3.7e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ05813.1 - 6.7e-26 91.3 0.0 1.2e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 OAJ05813.1 - 0.44 9.7 0.2 32 3.6 0.0 2.9 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase HTH_29 PF13551.1 OAJ05818.1 - 9.1e-07 29.0 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ05818.1 - 4.4e-05 24.1 0.1 0.00013 22.6 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 OAJ05818.1 - 0.00045 20.1 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Mga PF05043.8 OAJ05818.1 - 0.032 14.4 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_Crp_2 PF13545.1 OAJ05818.1 - 0.043 13.6 0.1 0.092 12.5 0.1 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_11 PF08279.7 OAJ05818.1 - 0.059 13.0 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 HTH domain SpoIIID PF12116.3 OAJ05818.1 - 0.061 13.2 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D HTH_DeoR PF08220.7 OAJ05818.1 - 0.084 12.4 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_1 PF00126.22 OAJ05818.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Pkinase PF00069.20 OAJ05819.1 - 5.1e-66 222.4 0.0 6.6e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05819.1 - 1.3e-28 99.8 0.0 1.8e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ05819.1 - 1.1e-12 48.2 0.6 1.1e-12 48.2 0.4 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ05819.1 - 7.5e-09 34.9 0.0 1.3e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 OAJ05819.1 - 1.9e-05 24.4 0.5 0.11 12.3 0.1 2.7 2 0 0 2 2 2 2 C2 domain APH PF01636.18 OAJ05819.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Isochorismatase PF00857.15 OAJ05820.1 - 6.3e-06 26.2 0.0 3.4e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Isochorismatase family DUF4526 PF15029.1 OAJ05820.1 - 0.4 10.2 2.0 0.62 9.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) UTP15_C PF09384.5 OAJ05821.1 - 2.4e-37 127.8 0.0 3.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 OAJ05821.1 - 1.1e-29 101.1 5.3 9.3e-10 38.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 OAJ05821.1 - 0.012 13.8 1.0 2.5 6.1 0.3 3.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 ANTH PF07651.11 OAJ05823.1 - 1.3e-69 234.0 0.1 1.3e-69 234.0 0.1 2.6 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 OAJ05823.1 - 9.7e-63 210.6 9.8 9.7e-63 210.6 6.8 4.7 5 1 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 OAJ05823.1 - 2e-08 34.1 1.2 3.2e-07 30.2 0.0 3.4 3 0 0 3 3 3 1 ENTH domain FlaC_arch PF05377.6 OAJ05823.1 - 0.87 9.5 10.0 0.66 9.9 0.2 4.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF1752 PF08550.5 OAJ05824.1 - 4.4e-10 38.9 3.2 7.9e-10 38.1 2.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1751 PF08551.5 OAJ05825.1 - 7.5e-26 90.3 7.4 1.5e-25 89.4 5.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 OAJ05825.1 - 0.00051 20.0 11.4 0.0015 18.5 7.9 1.8 1 1 0 1 1 1 1 Rhomboid family MSP1_C PF07462.6 OAJ05825.1 - 0.46 8.8 3.1 0.63 8.3 2.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2305 PF10230.4 OAJ05826.1 - 4.6e-47 160.6 0.0 3.3e-46 157.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 OAJ05826.1 - 1e-08 35.3 0.9 1.7e-08 34.6 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ05826.1 - 8.6e-06 25.5 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ05826.1 - 0.038 13.5 0.0 0.096 12.2 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 OAJ05826.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.3 OAJ05826.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RdRP PF05183.7 OAJ05827.1 - 1.2e-146 489.8 0.0 1.6e-146 489.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 OAJ05827.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05827.1 - 0.16 12.0 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DDE_3 PF13358.1 OAJ05828.1 - 3.7e-30 104.5 0.0 5.6e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.1 OAJ05828.1 - 5.4e-09 36.7 0.2 2.9e-07 31.1 0.0 2.8 1 1 1 2 2 2 2 Homeodomain-like domain HTH_29 PF13551.1 OAJ05828.1 - 2.5e-07 30.8 0.2 6.7e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ05828.1 - 5.5e-07 29.7 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.1 OAJ05828.1 - 6.2e-07 28.8 0.0 1.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 OAJ05828.1 - 0.00046 19.0 0.1 0.057 12.1 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain DDE_1 PF03184.14 OAJ05828.1 - 0.0032 16.6 0.0 0.0044 16.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_IS630 PF01710.11 OAJ05828.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase Mga PF05043.8 OAJ05828.1 - 0.059 13.6 0.0 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 Mga helix-turn-helix domain HTH_28 PF13518.1 OAJ05828.1 - 0.069 13.1 2.1 0.11 12.5 0.3 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain KH_3 PF13014.1 OAJ05828.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 KH domain HECT PF00632.20 OAJ05829.1 - 0.047 12.8 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) zf-CCCH PF00642.19 OAJ05830.1 - 3.2e-22 77.7 33.6 1.1e-06 28.1 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 OAJ05830.1 - 3e-06 26.8 1.1 3e-06 26.8 0.8 2.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ05830.1 - 0.048 13.4 4.2 0.088 12.5 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF4058 PF13267.1 OAJ05831.1 - 0.039 13.0 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) APG9 PF04109.11 OAJ05831.1 - 0.8 8.5 0.3 1.2 7.9 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg9 LtrA PF06772.6 OAJ05832.1 - 1.1e-17 63.9 15.9 1.6e-17 63.4 10.6 1.3 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) GARS_A PF01071.14 OAJ05833.1 - 5.1e-69 231.7 0.0 7.5e-69 231.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 OAJ05833.1 - 1.5e-31 108.7 0.0 4.4e-31 107.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 OAJ05833.1 - 2.5e-27 94.8 0.1 6.5e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS_C PF02769.17 OAJ05833.1 - 1.5e-25 89.9 0.0 3.2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 OAJ05833.1 - 2.3e-16 59.7 1.1 2.3e-16 59.7 0.7 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 OAJ05833.1 - 0.00021 21.0 0.0 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain BRCA2 PF00634.13 OAJ05833.1 - 0.031 13.5 0.1 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat Shikimate_DH PF01488.15 OAJ05833.1 - 0.046 13.8 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.27 OAJ05834.1 - 6.5e-24 82.8 6.8 1.6e-09 37.2 0.2 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 OAJ05834.1 - 7.8e-21 73.7 0.0 2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TFIIF_alpha PF05793.7 OAJ05834.1 - 0.24 9.7 29.1 0.11 10.8 14.1 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) adh_short PF00106.20 OAJ05835.1 - 1.2e-17 64.3 0.0 1.9e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ05835.1 - 1.2e-07 31.7 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ05835.1 - 0.00035 20.2 0.5 0.0023 17.6 0.4 2.1 1 1 0 1 1 1 1 KR domain 4HBT_2 PF13279.1 OAJ05836.1 - 1.7e-17 63.9 0.0 2.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 OAJ05836.1 - 0.00014 20.9 0.1 0.00075 18.5 0.0 2.0 2 1 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.17 OAJ05836.1 - 0.0032 17.5 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily WD40 PF00400.27 OAJ05837.1 - 3.1e-53 175.8 21.8 2.2e-09 36.8 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Sfi1 PF08457.5 OAJ05837.1 - 0.047 12.0 0.2 0.061 11.7 0.1 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein MMR_HSR1 PF01926.18 OAJ05838.1 - 1.2e-12 47.7 0.0 8.9e-12 44.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ05838.1 - 0.00057 19.2 0.1 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ05838.1 - 0.0011 18.8 0.1 0.0035 17.1 0.1 1.9 1 0 0 1 1 1 1 Dynamin family DUF258 PF03193.11 OAJ05838.1 - 0.1 11.7 0.1 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ05838.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SspB PF04386.8 OAJ05838.1 - 0.59 9.7 5.4 0.32 10.5 0.2 2.6 2 0 0 2 2 2 0 Stringent starvation protein B NPL4 PF05021.10 OAJ05839.1 - 6e-84 281.7 0.0 5.7e-82 275.3 0.0 3.2 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.10 OAJ05839.1 - 1.3e-65 219.5 0.1 2e-65 218.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 OAJ05839.1 - 5.3e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.13 OAJ05839.1 - 0.0015 17.6 1.3 0.0015 17.6 0.9 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others UIM PF02809.15 OAJ05839.1 - 0.0046 16.4 0.6 0.02 14.3 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif Homeobox PF00046.24 OAJ05840.1 - 1.9e-15 56.2 0.8 4.2e-15 55.0 0.6 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 OAJ05840.1 - 0.00099 18.7 0.4 0.0025 17.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Sigma70_ner PF04546.8 OAJ05840.1 - 0.0072 15.9 1.9 0.017 14.7 1.3 1.6 1 0 0 1 1 1 1 Sigma-70, non-essential region PIF1 PF05970.9 OAJ05841.1 - 1.6e-107 359.6 0.0 2.1e-107 359.2 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ05841.1 - 1.6e-62 210.5 0.1 5.7e-62 208.7 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ05841.1 - 4.6e-07 28.0 0.0 9.2e-07 27.0 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 OAJ05841.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ05841.1 - 0.0012 18.5 0.5 0.0037 16.9 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 OAJ05841.1 - 0.0026 17.8 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.7 OAJ05841.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 OAJ05841.1 - 0.018 15.0 0.0 0.063 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain EFG_II PF14492.1 OAJ05843.1 - 0.093 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Elongation Factor G, domain II HTH_8 PF02954.14 OAJ05843.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Homeobox_KN PF05920.6 OAJ05844.1 - 3.2e-05 23.5 0.0 0.00015 21.3 0.0 2.3 1 1 0 1 1 1 1 Homeobox KN domain Nop14 PF04147.7 OAJ05844.1 - 0.2 9.5 1.8 0.3 8.9 1.3 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 OAJ05845.1 - 0.031 12.1 6.7 0.04 11.7 4.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pescadillo_N PF06732.6 OAJ05846.1 - 2.6e-116 387.8 0.0 6.2e-116 386.5 0.0 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 OAJ05846.1 - 4.2e-10 39.6 0.0 9.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PI3K_1B_p101 PF10486.4 OAJ05846.1 - 0.43 8.0 3.5 0.64 7.5 2.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-Di19 PF05605.7 OAJ05847.1 - 0.24 11.5 0.1 0.46 10.6 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CtnDOT_TraJ PF07863.6 OAJ05847.1 - 0.52 10.8 12.8 0.026 14.9 2.9 3.3 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon Pkr1 PF08636.5 OAJ05848.1 - 2.5e-20 72.3 2.2 2.9e-20 72.0 1.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 TGS PF02824.16 OAJ05849.1 - 3.3e-20 71.6 0.1 6.3e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 OAJ05849.1 - 3e-19 69.0 0.0 6.5e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ05849.1 - 3.8e-11 42.5 0.0 6.3e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 OAJ05849.1 - 0.00049 19.9 0.2 0.017 14.9 0.0 2.4 1 1 1 2 2 2 1 Dynamin family Miro PF08477.8 OAJ05849.1 - 0.026 15.0 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MCM PF00493.18 OAJ05849.1 - 0.034 12.9 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_16 PF13191.1 OAJ05849.1 - 0.085 12.8 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain zf-C4H2 PF10146.4 OAJ05850.1 - 0.016 15.2 6.3 1.3 8.9 1.9 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein PPR_2 PF13041.1 OAJ05850.1 - 0.14 12.1 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family Spc7 PF08317.6 OAJ05850.1 - 0.3 9.7 2.4 0.65 8.5 1.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1752 PF08550.5 OAJ05851.1 - 7.2e-10 38.2 3.2 1.3e-09 37.4 2.2 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Nop14 PF04147.7 OAJ05851.1 - 3.7 5.3 5.3 6.2 4.6 3.7 1.2 1 0 0 1 1 1 0 Nop14-like family zf-CCCH_2 PF14608.1 OAJ05852.1 - 1.9e-07 30.8 18.0 5.9e-06 26.0 4.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Ank_2 PF12796.2 OAJ05852.1 - 1.8e-06 28.1 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ05852.1 - 1.9e-06 27.3 0.0 4.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 OAJ05852.1 - 3.8e-05 23.5 0.0 8.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat zf-CCCH PF00642.19 OAJ05852.1 - 4.7e-05 22.9 11.2 0.0042 16.7 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_5 PF13857.1 OAJ05852.1 - 6.1e-05 23.1 0.0 0.00018 21.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 OAJ05852.1 - 0.00072 19.9 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RRM_1 PF00076.17 OAJ05853.1 - 2.7e-22 78.1 0.0 1.4e-11 43.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05853.1 - 2.7e-16 59.2 0.1 7.2e-08 32.3 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05853.1 - 6.1e-10 38.7 0.6 0.0056 16.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 OAJ05854.1 - 2.8e-72 243.4 0.0 3.8e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.19 OAJ05854.1 - 0.0009 18.6 6.6 28 4.4 0.3 6.5 8 1 0 8 8 8 1 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.20 OAJ05854.1 - 0.021 15.0 0.0 0.061 13.5 0.0 1.8 1 1 0 1 1 1 0 Phosphopantetheine attachment site DUF2207 PF09972.4 OAJ05854.1 - 2.9 6.3 5.1 8.1 4.9 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UQ_con PF00179.21 OAJ05855.1 - 7.6e-21 74.0 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 OAJ05855.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 UEV domain DUF2890 PF11081.3 OAJ05855.1 - 0.2 11.7 11.8 0.68 9.9 8.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 OAJ05855.1 - 0.31 10.2 20.1 2.6 7.2 12.9 2.2 2 0 0 2 2 2 0 SDA1 GOLD_2 PF13897.1 OAJ05855.1 - 0.36 11.0 5.9 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Nop14 PF04147.7 OAJ05855.1 - 1.3 6.8 17.1 1.9 6.2 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 OAJ05855.1 - 2.4 6.7 19.5 4.6 5.8 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 OAJ05855.1 - 2.6 6.4 18.5 9.6 4.5 10.4 2.1 2 0 0 2 2 2 0 Daxx Family TLD PF07534.11 OAJ05856.1 - 8.1e-22 77.7 0.0 1.8e-19 70.1 0.0 2.7 2 0 0 2 2 2 2 TLD Glyco_hydro_3 PF00933.16 OAJ05857.1 - 1.6e-50 171.7 2.7 1.7e-49 168.4 0.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 OAJ05857.1 - 0.84 9.1 6.5 0.17 11.3 0.1 2.9 4 0 0 4 4 4 0 Glycosyl hydrolase family 3 C-terminal domain CtaG_Cox11 PF04442.9 OAJ05858.1 - 4.8e-52 175.7 0.0 8.7e-52 174.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Acetyltransf_1 PF00583.19 OAJ05859.1 - 1.1e-15 57.3 0.1 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 OAJ05859.1 - 1.5e-10 41.2 0.0 2.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 OAJ05859.1 - 6.3e-09 35.4 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 OAJ05859.1 - 2e-08 34.2 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 OAJ05859.1 - 1.1e-07 32.1 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ05859.1 - 9.6e-07 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 OAJ05859.1 - 4.7e-06 26.6 0.0 7.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 OAJ05859.1 - 0.0016 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 OAJ05859.1 - 0.011 15.7 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec3_C PF09763.4 OAJ05860.1 - 1.3e-87 294.6 0.0 2e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 OAJ05860.1 - 6.5e-19 67.5 0.0 1.2e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 OAJ05860.1 - 0.0024 16.4 0.4 0.0035 15.9 0.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Peptidase_M27 PF01742.12 OAJ05860.1 - 0.2 10.5 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease Ipi1_N PF12333.3 OAJ05861.1 - 8.7e-11 41.7 0.1 5.6e-09 35.8 0.1 3.3 1 1 1 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CENP-B_dimeris PF09026.5 OAJ05861.1 - 0.0081 16.3 3.2 0.016 15.4 2.2 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ05861.1 - 0.013 15.7 2.9 0.03 14.6 2.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_71 PF03659.9 OAJ05861.1 - 0.088 11.2 0.1 0.13 10.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 Nucleoplasmin PF03066.10 OAJ05861.1 - 0.14 11.6 3.4 0.32 10.5 2.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin FLO_LFY PF01698.11 OAJ05861.1 - 0.18 10.6 0.1 0.31 9.8 0.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 OAJ05861.1 - 0.21 10.4 1.1 0.38 9.5 0.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sigma70_ner PF04546.8 OAJ05861.1 - 0.47 10.0 4.7 1.1 8.7 3.3 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Nudix_N_2 PF14803.1 OAJ05863.1 - 0.079 12.6 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Nudix N-terminal TALPID3 PF15324.1 OAJ05864.1 - 0.85 6.8 5.6 1.4 6.1 3.9 1.2 1 0 0 1 1 1 0 Hedgehog signalling target DrrA_P4M PF14860.1 OAJ05871.1 - 0.0027 17.4 1.1 0.0047 16.6 0.8 1.3 1 0 0 1 1 1 1 DrrA phosphatidylinositol 4-phosphate binding domain AIP3 PF03915.8 OAJ05871.1 - 0.0033 16.3 1.1 0.0038 16.2 0.8 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 FTA4 PF13093.1 OAJ05871.1 - 0.0035 16.7 0.8 0.0053 16.2 0.6 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3584 PF12128.3 OAJ05871.1 - 0.0083 13.5 6.1 0.01 13.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CAMP_factor PF07373.6 OAJ05871.1 - 0.023 14.1 1.0 0.03 13.8 0.7 1.2 1 0 0 1 1 1 0 CAMP factor (Cfa) Jnk-SapK_ap_N PF09744.4 OAJ05871.1 - 0.026 14.5 1.7 0.039 13.9 1.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UBN2_3 PF14244.1 OAJ05871.1 - 0.029 13.9 0.3 0.045 13.3 0.2 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TMPIT PF07851.8 OAJ05871.1 - 0.067 12.2 1.3 0.09 11.8 0.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein LemA PF04011.7 OAJ05871.1 - 0.12 11.4 1.5 0.24 10.4 0.8 1.5 1 1 0 1 1 1 0 LemA family Baculo_PEP_C PF04513.7 OAJ05871.1 - 0.24 11.1 4.7 0.81 9.4 3.2 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.9 OAJ05871.1 - 0.48 9.8 3.5 0.69 9.3 1.7 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain PIF1 PF05970.9 OAJ05872.1 - 5.4e-21 74.9 0.0 8.6e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ05872.1 - 1.1e-12 47.9 0.1 4.3e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 OAJ05872.1 - 3.8e-09 36.5 0.0 1.5e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.1 OAJ05872.1 - 4.1e-07 29.6 0.1 1.2e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Torsin PF06309.6 OAJ05872.1 - 0.00014 21.7 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.1 OAJ05872.1 - 0.0011 19.0 0.4 0.0077 16.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain ResIII PF04851.10 OAJ05872.1 - 0.0033 17.2 0.2 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.1 OAJ05872.1 - 0.032 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAJ05872.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ05872.1 - 0.06 13.0 0.2 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 OAJ05872.1 - 0.079 11.9 0.0 0.86 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 OAJ05872.1 - 0.08 11.5 0.2 0.21 10.1 0.0 1.7 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 OAJ05872.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2392 PF10288.4 OAJ05879.1 - 0.0038 17.5 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) TFIIE-A_C-term PF11521.3 OAJ05879.1 - 0.0096 15.8 3.5 2.1 8.3 1.1 2.9 2 0 0 2 2 2 2 C-terminal general transcription factor TFIIE alpha RNA_pol_3_Rpc31 PF11705.3 OAJ05879.1 - 0.069 13.0 10.0 0.16 11.9 3.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 OAJ05879.1 - 0.17 12.1 9.4 0.6 10.3 3.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 OAJ05879.1 - 0.75 10.1 9.7 18 5.7 4.3 2.8 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ05879.1 - 6.2 6.3 9.6 23 4.4 5.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin hGDE_N PF14699.1 OAJ05880.1 - 0.034 13.9 0.1 0.68 9.8 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain from the human glycogen debranching enzyme PPC PF04151.10 OAJ05880.1 - 0.16 12.9 3.7 6.3 7.8 0.1 4.4 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain Glyco_hydro_20 PF00728.17 OAJ05881.1 - 1.3e-81 274.4 0.0 1.6e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 OAJ05881.1 - 2.2e-14 54.2 0.0 3.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 OAJ05881.1 - 0.00095 19.7 0.1 0.012 16.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 NADH_Oxid_Nqo15 PF11497.3 OAJ05881.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 2-Hacid_dh_C PF02826.14 OAJ05882.1 - 3.9e-35 120.5 0.0 5.9e-34 116.7 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ05882.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.25 OAJ05882.1 - 0.00037 19.9 0.0 0.00052 19.4 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF4159 PF13709.1 OAJ05882.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Mitochondr_Som1 PF11093.3 OAJ05883.1 - 2.5e-09 36.8 0.1 3.4e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Mito_carr PF00153.22 OAJ05884.1 - 2.4e-57 190.6 2.1 4.6e-19 67.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2361 PF10153.4 OAJ05885.1 - 7.2e-18 64.8 2.2 7.2e-18 64.8 1.5 2.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Bromodomain PF00439.20 OAJ05886.1 - 2.9e-22 78.3 0.2 6e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 OAJ05886.1 - 2.1e-06 27.3 0.2 6.8e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated Mito_carr PF00153.22 OAJ05887.1 - 1e-66 220.6 0.6 4.7e-25 87.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.17 OAJ05888.1 - 1.2e-07 31.9 11.8 0.00018 21.5 0.4 2.7 2 1 0 2 2 2 2 Rhomboid family Pyridox_oxidase PF01243.15 OAJ05890.1 - 1.1e-07 31.8 0.0 2.5e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Kinesin PF00225.18 OAJ05891.1 - 3.7e-109 364.4 0.0 5.9e-109 363.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 OAJ05891.1 - 4.2e-31 107.4 0.0 9.8e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 OAJ05891.1 - 2.5e-15 56.5 0.0 6.9e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 OAJ05891.1 - 8.6e-11 41.6 0.1 2.4e-10 40.2 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 OAJ05891.1 - 1.9e-06 27.9 0.0 9.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.1 OAJ05891.1 - 0.00027 21.1 0.1 0.001 19.2 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain tRNA-synt_2b PF00587.20 OAJ05892.1 - 3.1e-30 105.0 0.1 5.4e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 OAJ05892.1 - 2.2e-05 24.2 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain eIF-5_eIF-2B PF01873.12 OAJ05893.1 - 1.6e-45 153.8 0.5 2.5e-45 153.1 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 OAJ05893.1 - 0.00091 18.4 0.1 0.0017 17.6 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding PITH PF06201.8 OAJ05894.1 - 7.8e-35 119.8 0.0 1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Nodulin_late PF07127.6 OAJ05895.1 - 0.26 11.4 3.9 1.2 9.2 0.1 2.8 3 0 0 3 3 3 0 Late nodulin protein Pyridox_oxidase PF01243.15 OAJ05896.1 - 1.7e-11 43.9 0.0 3e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Dppa2_A PF14049.1 OAJ05896.1 - 0.024 14.4 0.3 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates WD40 PF00400.27 OAJ05897.1 - 5.7e-49 162.3 25.1 4.4e-10 39.0 0.6 10.9 12 0 0 12 12 12 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 OAJ05897.1 - 0.11 12.0 0.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Prenyltrans PF00432.16 OAJ05898.1 - 2.4e-29 100.5 5.7 2.8e-07 29.9 0.0 6.6 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 OAJ05898.1 - 6.2e-28 96.9 0.2 8.6e-13 48.2 0.0 5.9 3 3 3 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 OAJ05898.1 - 5.2e-27 94.4 0.1 4.3e-09 36.7 0.1 4.8 2 2 2 4 4 4 4 Prenyltransferase-like Pec_lyase PF09492.5 OAJ05898.1 - 1e-09 37.9 0.2 0.017 14.3 0.0 4.6 2 2 3 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 OAJ05898.1 - 1.1e-05 24.7 0.1 0.2 10.8 0.0 3.7 2 1 1 3 3 3 2 A-macroglobulin complement component SNF5 PF04855.7 OAJ05900.1 - 3e-71 239.7 1.6 3e-71 239.7 1.1 2.4 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 OAJ05900.1 - 0.0024 17.1 1.2 0.0054 16.0 0.8 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1115 PF06544.7 OAJ05900.1 - 2.2 7.9 5.4 8.2 6.1 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) zf-HIT PF04438.11 OAJ05900.1 - 4.1 7.1 2.1 4.6 6.9 0.3 1.8 2 0 0 2 2 2 0 HIT zinc finger Proteasome PF00227.21 OAJ05901.1 - 1.1e-32 112.8 0.0 1.5e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.17 OAJ05903.1 - 1.9e-33 113.9 0.0 1.2e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05903.1 - 1e-22 79.8 0.0 3.4e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05903.1 - 6.8e-17 61.0 0.0 3.1e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 OAJ05903.1 - 0.063 12.7 0.3 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain cwf18 PF08315.7 OAJ05904.1 - 8.7e-26 90.8 7.7 1.1e-25 90.5 5.4 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DUF2630 PF10944.3 OAJ05904.1 - 1.5 9.0 5.8 15 5.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) zf-C2H2_jaz PF12171.3 OAJ05905.1 - 2.4e-07 30.7 0.1 3.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ05905.1 - 4.5e-05 23.4 0.2 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 OAJ05905.1 - 0.00036 20.1 0.5 0.00077 19.0 0.1 1.7 2 0 0 2 2 2 1 DBF zinc finger DUF1777 PF08648.7 OAJ05905.1 - 0.0069 16.1 6.1 0.0069 16.1 4.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) Flavodoxin_5 PF12724.2 OAJ05905.1 - 0.13 12.2 1.4 2.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain zf-C2H2 PF00096.21 OAJ05905.1 - 0.15 12.4 0.6 0.27 11.6 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3340 PF11818.3 OAJ05905.1 - 3.4 7.6 16.7 0.61 10.0 1.8 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) PIG-L PF02585.12 OAJ05906.1 - 1.6e-24 86.8 0.0 2.5e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase tRNA-synt_1 PF00133.17 OAJ05907.1 - 1.6e-221 736.4 0.0 2.1e-221 736.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 OAJ05907.1 - 9.4e-23 80.6 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 OAJ05907.1 - 1.8e-15 56.5 2.1 7.8e-06 24.7 0.3 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 OAJ05907.1 - 0.022 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Phosducin PF02114.11 OAJ05908.1 - 1.6e-18 66.4 0.8 2.4e-08 33.0 0.0 3.2 3 0 0 3 3 3 3 Phosducin AA_permease_2 PF13520.1 OAJ05911.1 - 9.2e-77 258.3 36.2 1.2e-76 257.9 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ05911.1 - 1e-19 70.2 27.5 1e-19 70.2 19.1 2.0 1 1 1 2 2 2 2 Amino acid permease Metallopep PF12044.3 OAJ05912.1 - 2.9e-88 296.1 0.0 5.3e-38 130.5 0.0 3.0 3 0 0 3 3 3 3 Putative peptidase family Jacalin PF01419.12 OAJ05912.1 - 5e-10 39.3 0.0 0.00011 22.0 0.0 3.0 3 0 0 3 3 3 2 Jacalin-like lectin domain Peptidase_M66 PF10462.4 OAJ05912.1 - 0.0045 15.8 0.1 0.0091 14.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase M66 Methyltransf_11 PF08241.7 OAJ05913.1 - 9.6e-11 42.0 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ05913.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05913.1 - 2.8e-07 31.0 0.0 7.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ05913.1 - 1.6e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ05913.1 - 4.1e-05 23.8 0.0 7.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ05913.1 - 7.3e-05 22.4 0.0 0.0003 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ05913.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 OAJ05913.1 - 0.00019 21.4 0.0 0.00058 19.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ05913.1 - 0.0067 15.8 0.1 0.046 13.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase small domain Ank_2 PF12796.2 OAJ05914.1 - 7.1e-16 58.3 3.6 5.1e-10 39.5 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 OAJ05914.1 - 2.5e-12 45.7 0.4 1.5e-05 24.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 OAJ05914.1 - 8.8e-12 44.2 0.9 5.5e-07 29.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 OAJ05914.1 - 1.2e-11 44.7 2.4 2.9e-09 37.1 0.4 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ05914.1 - 1.8e-10 40.6 3.7 1.8e-05 24.7 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Borrelia_P83 PF05262.6 OAJ05914.1 - 0.072 11.3 5.4 0.083 11.1 3.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF77 PF01910.12 OAJ05914.1 - 0.11 12.2 0.3 0.39 10.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF77 Rtf2 PF04641.7 OAJ05914.1 - 0.23 10.6 5.1 0.63 9.1 3.4 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger ATP_bind_1 PF03029.12 OAJ05915.1 - 1.8e-73 247.0 0.0 2.2e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 OAJ05915.1 - 2.2e-05 25.2 0.0 6e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ05915.1 - 0.0044 16.2 0.0 0.0079 15.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ArgK PF03308.11 OAJ05915.1 - 0.0049 15.6 0.0 0.01 14.6 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_19 PF13245.1 OAJ05915.1 - 0.0052 16.5 0.1 0.027 14.1 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain CbiA PF01656.18 OAJ05915.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 OAJ05915.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 OAJ05915.1 - 0.019 14.8 0.3 0.085 12.8 0.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 OAJ05915.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 OAJ05915.1 - 0.08 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MIP-T3 PF10243.4 OAJ05916.1 - 1.6e-06 26.9 34.4 1.6e-06 26.9 23.8 3.3 2 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 OAJ05917.1 - 1e-28 98.8 5.7 5e-14 51.7 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein TPR_12 PF13424.1 OAJ05918.1 - 8e-66 217.9 95.9 7.1e-10 38.6 4.9 13.7 6 4 9 16 16 16 15 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ05918.1 - 2.3e-62 205.2 110.0 6.1e-06 25.9 2.5 20.7 21 0 0 21 21 21 18 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ05918.1 - 1.1e-20 71.7 47.4 0.062 13.2 0.2 18.3 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05918.1 - 2.8e-16 58.9 70.6 0.0034 17.0 0.7 12.9 7 5 5 14 14 14 10 TPR repeat TPR_1 PF00515.23 OAJ05918.1 - 4.7e-10 38.6 24.5 0.13 11.9 0.1 14.5 17 0 0 17 17 16 2 Tetratricopeptide repeat DUF3856 PF12968.2 OAJ05918.1 - 5.7e-07 29.4 39.8 0.0019 18.0 0.5 8.3 4 2 4 9 9 9 3 Domain of Unknown Function (DUF3856) TPR_8 PF13181.1 OAJ05918.1 - 9.5e-07 28.1 38.3 3 7.8 0.0 15.5 17 1 1 18 18 17 3 Tetratricopeptide repeat Rapsyn_N PF10579.4 OAJ05918.1 - 0.0025 17.5 0.1 19 5.1 0.0 5.4 6 0 0 6 6 5 0 Rapsyn N-terminal myristoylation and linker region TPR_4 PF07721.9 OAJ05918.1 - 0.0048 17.2 31.8 1.5 9.4 0.4 12.5 14 0 0 14 14 12 1 Tetratricopeptide repeat Ssu72 PF04722.8 OAJ05918.1 - 0.0097 15.2 1.6 21 4.3 0.0 5.8 5 1 0 6 6 6 0 Ssu72-like protein BUD22 PF09073.5 OAJ05918.1 - 0.014 14.4 0.4 6.2 5.7 0.0 3.4 4 0 0 4 4 4 0 BUD22 Prefoldin_2 PF01920.15 OAJ05918.1 - 0.11 12.2 12.8 2.3 8.0 0.0 6.0 7 0 0 7 7 7 0 Prefoldin subunit DUF4645 PF15488.1 OAJ05918.1 - 0.14 11.3 8.2 15 4.6 0.0 5.6 3 2 4 7 7 7 0 Domain of unknown function (DUF4645) SHNi-TPR PF10516.4 OAJ05918.1 - 2.9 7.2 38.7 2.4 7.4 0.2 10.5 13 1 1 14 14 14 0 SHNi-TPR DUF4202 PF13875.1 OAJ05919.1 - 5e-55 186.0 0.0 8.3e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.7 OAJ05919.1 - 2.9e-15 56.5 0.0 7.6e-13 48.7 0.0 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ05919.1 - 1.4e-14 54.1 0.0 8.1e-14 51.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ05919.1 - 8.4e-09 35.8 0.0 8.8e-07 29.3 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ05919.1 - 1.7e-07 30.9 0.0 1.4e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ05919.1 - 5.2e-07 29.9 0.0 2.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ05919.1 - 1.5e-06 28.7 0.0 6e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ05919.1 - 0.0021 18.8 0.0 0.016 16.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 OAJ05919.1 - 0.003 16.9 0.2 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 OAJ05919.1 - 0.0057 16.6 0.0 0.021 14.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 OAJ05919.1 - 0.055 12.4 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family SQS_PSY PF00494.14 OAJ05920.1 - 4.1e-52 177.0 1.4 2e-51 174.8 1.0 2.0 1 1 0 1 1 1 1 Squalene/phytoene synthase HAMP PF00672.20 OAJ05921.1 - 1.1e-45 153.7 19.6 1.2e-07 31.8 0.1 8.0 7 0 0 7 7 7 7 HAMP domain Response_reg PF00072.19 OAJ05921.1 - 1.9e-27 95.5 1.1 1.3e-24 86.3 0.3 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 OAJ05921.1 - 2.9e-27 94.5 0.0 1.1e-26 92.6 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 OAJ05921.1 - 6.1e-17 61.3 0.3 4.9e-16 58.4 0.2 2.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pox_A_type_inc PF04508.7 OAJ05921.1 - 0.075 12.8 0.2 1 9.3 0.0 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PMC2NT PF08066.7 OAJ05921.1 - 0.077 13.2 2.7 4.6 7.6 0.0 4.2 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Syntaxin PF00804.20 OAJ05921.1 - 1.7 8.8 6.5 16 5.6 1.1 4.5 3 2 0 3 3 3 0 Syntaxin Adaptin_N PF01602.15 OAJ05922.1 - 8.6e-131 436.8 8.1 1.9e-130 435.7 5.6 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ05922.1 - 7.9e-26 90.9 3.0 1e-24 87.3 0.2 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ05922.1 - 2.6e-16 59.6 9.4 3e-10 40.2 0.3 4.8 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.17 OAJ05922.1 - 1.5e-10 40.2 2.3 0.0046 16.9 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 OAJ05922.1 - 4.5e-06 26.2 3.6 0.005 16.6 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 OAJ05922.1 - 0.00014 22.1 9.1 0.25 11.8 0.1 5.9 7 1 1 8 8 8 2 HEAT-like repeat Arm_2 PF04826.8 OAJ05922.1 - 0.001 18.2 0.0 0.0022 17.1 0.0 1.5 1 0 0 1 1 1 1 Armadillo-like MFS_1 PF07690.11 OAJ05923.1 - 5.3e-17 61.5 45.8 5.3e-17 61.5 31.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ05923.1 - 0.01 15.6 0.7 0.048 13.4 0.5 2.3 1 1 0 1 1 1 0 MFS_1 like family Lipase_GDSL_2 PF13472.1 OAJ05924.1 - 9.9e-07 29.0 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 OAJ05924.1 - 4.4e-06 26.7 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CRAL_TRIO PF00650.15 OAJ05925.1 - 2.2e-30 105.2 0.1 3.5e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 OAJ05925.1 - 3.3e-11 43.2 0.0 5.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ05925.1 - 3.6e-07 30.1 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Nop14 PF04147.7 OAJ05925.1 - 0.17 9.8 8.5 0.22 9.3 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ05925.1 - 0.21 10.8 9.9 0.37 10.0 6.9 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 OAJ05925.1 - 0.56 8.6 13.0 1 7.7 9.0 1.3 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 OAJ05925.1 - 2.2 8.0 15.4 0.04 13.8 4.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_8 PF01501.15 OAJ05926.1 - 1.7e-29 102.9 0.0 5.7e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 OAJ05926.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Thiol_cytolysin PF01289.14 OAJ05926.1 - 0.057 11.7 0.0 0.085 11.2 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin ATP-synt PF00231.14 OAJ05927.1 - 4.2e-67 226.5 3.0 5.1e-67 226.2 2.1 1.1 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.5 OAJ05927.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain LSM PF01423.17 OAJ05928.1 - 1.7e-15 56.2 0.0 2.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 LSM domain DUF3510 PF12022.3 OAJ05928.1 - 0.00072 19.6 0.0 0.00086 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GRP PF07172.6 OAJ05928.1 - 1.9 9.0 28.9 2.7 8.5 20.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family Rrn6 PF10214.4 OAJ05935.1 - 2.9e-06 25.7 0.7 0.072 11.1 0.0 3.3 2 2 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Peripla_BP_5 PF13433.1 OAJ05935.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain AMP-binding PF00501.23 OAJ05937.1 - 1.2e-59 201.7 0.1 2e-59 201.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ05937.1 - 2.5e-18 66.7 0.4 6.6e-18 65.4 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RVT_1 PF00078.22 OAJ05939.1 - 1.6e-05 24.3 0.0 7.1e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ins_allergen_rp PF06757.8 OAJ05939.1 - 0.079 12.4 0.0 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification TB2_DP1_HVA22 PF03134.14 OAJ05940.1 - 8.7e-32 108.7 5.0 1.1e-31 108.3 3.5 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC2_membrane_3 PF12698.2 OAJ05940.1 - 0.49 9.3 7.3 0.64 8.9 5.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Steroid_dh PF02544.11 OAJ05942.1 - 4.2e-23 81.7 1.2 1.3e-07 31.4 0.2 4.2 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 OAJ05942.1 - 0.0063 15.8 0.5 0.023 14.0 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) CKS PF01111.14 OAJ05943.1 - 8.1e-36 121.6 0.2 1.1e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Pkinase PF00069.20 OAJ05944.1 - 5e-43 147.1 0.0 6.7e-26 90.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05944.1 - 1e-15 57.5 0.0 6.5e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 OAJ05944.1 - 0.0039 16.9 0.5 0.38 10.4 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family PAS_9 PF13426.1 OAJ05945.1 - 2.5e-26 92.0 0.0 8e-16 58.3 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.19 OAJ05945.1 - 6.1e-15 54.9 0.0 1.8e-09 37.3 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.6 OAJ05945.1 - 3e-12 46.4 0.0 3.3e-07 30.3 0.0 4.3 3 1 1 4 4 4 2 PAS fold PAS_4 PF08448.5 OAJ05945.1 - 1e-06 28.7 0.2 0.0015 18.5 0.0 5.0 5 0 0 5 5 5 1 PAS fold PAS_8 PF13188.1 OAJ05945.1 - 5.8e-06 25.9 0.0 0.0025 17.6 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 OAJ05945.1 - 0.00011 22.1 0.0 0.00076 19.4 0.0 2.6 1 1 0 1 1 1 1 PAS domain ATP-synt_10 PF05176.9 OAJ05947.1 - 8.8e-48 162.7 0.0 3.2e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein DUF1253 PF06862.7 OAJ05949.1 - 3.7e-130 434.2 0.0 5.1e-130 433.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) AICARFT_IMPCHas PF01808.13 OAJ05950.1 - 6.3e-105 350.7 0.1 8.1e-105 350.3 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 OAJ05950.1 - 1.9e-21 75.8 0.0 3.7e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain AMP-binding PF00501.23 OAJ05951.1 - 5.5e-228 756.3 0.0 2.6e-80 269.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 OAJ05951.1 - 2.1e-106 355.1 0.0 3.1e-29 101.7 0.1 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 OAJ05951.1 - 1.4e-33 114.9 0.8 2.5e-07 30.8 0.0 5.1 4 0 0 4 4 4 4 Phosphopantetheine attachment site zf-RAG1 PF10426.4 OAJ05951.1 - 2.9 7.9 3.9 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Peptidase_M50B PF13398.1 OAJ05952.1 - 2e-54 184.0 15.0 2.6e-54 183.6 10.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like TPR_2 PF07719.12 OAJ05953.1 - 8e-08 31.6 6.4 0.056 13.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ05953.1 - 1.9e-06 27.7 12.6 0.046 13.6 0.0 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ05953.1 - 8.5e-06 25.5 10.1 0.029 14.3 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ05953.1 - 0.001 19.7 17.7 2.2 9.0 0.0 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ05953.1 - 0.0012 18.4 3.5 2.2 7.9 0.0 4.6 5 1 1 6 6 6 2 TPR repeat TPR_7 PF13176.1 OAJ05953.1 - 0.017 14.9 0.3 0.5 10.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ05953.1 - 0.025 15.1 19.0 4.5 8.1 0.0 8.1 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ05953.1 - 0.052 13.3 0.0 1.9 8.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ05953.1 - 0.064 12.8 0.2 3.5 7.4 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ05953.1 - 0.22 11.8 10.5 3.4 8.0 0.0 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat Aa_trans PF01490.13 OAJ05954.1 - 1.7e-33 115.6 31.5 2.1e-33 115.4 21.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PsbI PF02532.9 OAJ05954.1 - 0.057 13.0 2.6 0.27 10.9 1.8 2.2 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) P16-Arc PF04699.9 OAJ05955.1 - 8.5e-49 165.4 0.0 9.4e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 OAJ05955.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family Lipase_3 PF01764.20 OAJ05956.1 - 1.7e-23 82.7 0.0 2.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ05956.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ05957.1 - 9.9e-21 73.8 0.1 1.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ05957.1 - 0.09 12.5 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M16 PF00675.15 OAJ05958.1 - 1.4e-41 141.7 0.2 8.9e-41 139.1 0.0 2.5 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ05958.1 - 2.8e-37 128.1 0.1 2.5e-21 76.1 0.0 4.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain SET PF00856.23 OAJ05959.1 - 0.0043 17.3 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 2 SET domain Pyrid_oxidase_2 PF13883.1 OAJ05960.1 - 1.5e-24 86.6 0.0 2.7e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GDI PF00996.13 OAJ05961.1 - 5e-196 651.2 0.0 6e-196 650.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor p450 PF00067.17 OAJ05962.1 - 2e-22 79.3 0.0 4.2e-22 78.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ05963.1 - 4.5e-23 81.5 0.0 6.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.23 OAJ05964.1 - 7.8e-61 206.4 0.0 2.6e-60 204.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3617 PF12276.3 OAJ05964.1 - 0.19 11.1 0.9 0.41 10.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Utp14 PF04615.8 OAJ05965.1 - 1.3 7.0 14.1 1.6 6.7 9.8 1.2 1 0 0 1 1 1 0 Utp14 protein RP-C_C PF11800.3 OAJ05965.1 - 2.2 7.9 13.7 4.4 6.9 0.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Velvet PF11754.3 OAJ05965.1 - 4.7 6.7 6.4 13 5.3 4.5 1.7 1 1 0 1 1 1 0 Velvet factor Daxx PF03344.10 OAJ05965.1 - 7.8 4.8 14.3 8.4 4.7 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Bul1_N PF04425.7 OAJ05966.1 - 1.4 7.3 3.4 6.6 5.1 0.1 2.2 2 0 0 2 2 2 0 Bul1 N terminus SDA1 PF05285.7 OAJ05966.1 - 10 5.3 9.5 1.2 8.3 0.0 2.3 1 1 1 2 2 2 0 SDA1 Wzz PF02706.10 OAJ05967.1 - 0.12 12.1 0.4 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Chain length determinant protein Nucleoplasmin PF03066.10 OAJ05967.1 - 0.42 10.1 6.7 0.73 9.3 2.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin DUF572 PF04502.8 OAJ05967.1 - 1.5 7.9 4.8 0.31 10.1 0.9 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Sigma70_ner PF04546.8 OAJ05967.1 - 4.5 6.8 7.1 3.7 7.1 1.5 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 OAJ05967.1 - 7.3 6.8 8.7 17 5.6 3.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ECH PF00378.15 OAJ05968.1 - 1.2e-56 191.6 0.0 1.4e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 OAJ05968.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Amidase PF01425.16 OAJ05969.1 - 1e-90 304.7 0.1 1.2e-90 304.4 0.0 1.0 1 0 0 1 1 1 1 Amidase RTC4 PF14474.1 OAJ05970.1 - 1.7e-06 27.9 0.0 4.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain CCDC71L PF15374.1 OAJ05971.1 - 0.86 8.8 8.2 0.94 8.7 5.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF1067 PF06362.6 OAJ05971.1 - 1.3 9.6 4.2 0.81 10.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1067) Peptidase_S49_N PF08496.5 OAJ05971.1 - 1.9 8.2 7.8 2.4 7.9 5.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Topoisom_I_N PF02919.10 OAJ05971.1 - 1.9 7.7 10.8 2.4 7.3 7.4 1.3 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PBP1_TM PF14812.1 OAJ05972.1 - 0.26 11.6 10.8 1.5 9.1 7.5 2.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BCAS2 PF05700.6 OAJ05974.1 - 6.9e-38 130.3 5.2 7.7e-38 130.1 3.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) NTR2 PF15458.1 OAJ05974.1 - 0.032 13.4 1.9 0.33 10.1 0.2 2.2 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Enkurin PF13864.1 OAJ05974.1 - 1.5 9.0 5.4 0.5 10.5 0.5 2.4 2 1 1 3 3 3 0 Calmodulin-binding eIF-3_zeta PF05091.7 OAJ05977.1 - 1.1e-162 542.3 0.0 1.3e-160 535.4 0.0 2.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pam16 PF03656.8 OAJ05978.1 - 3.9e-13 49.3 4.8 4.7e-06 26.4 0.7 3.2 1 1 0 2 2 2 2 Pam16 Exo_endo_phos PF03372.18 OAJ05979.1 - 7.4e-21 75.2 0.1 1.4e-20 74.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 OAJ05979.1 - 2.6e-15 55.6 2.7 3.9e-07 29.5 0.2 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ05979.1 - 2.5e-08 33.5 5.4 4.3e-05 23.1 0.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 OAJ05979.1 - 0.00012 21.6 4.0 0.69 10.3 0.0 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 OAJ05979.1 - 0.00047 19.8 5.9 0.17 11.9 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich Repeat CENP-B_dimeris PF09026.5 OAJ05979.1 - 0.0058 16.8 6.3 0.014 15.6 4.4 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nop14 PF04147.7 OAJ05979.1 - 4.1 5.1 7.0 6.4 4.5 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family HATPase_c PF02518.21 OAJ05980.1 - 2e-31 107.9 0.1 3.3e-29 100.8 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ05980.1 - 1.8e-24 85.8 0.2 4.6e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.5 OAJ05980.1 - 2.4e-24 85.4 5.0 2e-13 50.3 0.1 6.6 6 0 0 6 6 6 4 PAS fold HisKA PF00512.20 OAJ05980.1 - 1.5e-20 72.9 0.1 6.1e-20 70.9 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 OAJ05980.1 - 5.3e-19 68.5 0.0 6.3e-12 45.7 0.0 4.7 5 0 0 5 5 5 3 PAS domain PAS_3 PF08447.6 OAJ05980.1 - 8.9e-14 51.3 0.5 2.6e-13 49.8 0.3 1.9 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 OAJ05980.1 - 1.9e-13 50.1 0.1 0.0016 18.2 0.0 5.3 5 0 0 5 5 5 3 PAS fold HATPase_c_3 PF13589.1 OAJ05980.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.1 OAJ05980.1 - 0.0066 16.7 0.2 7 6.9 0.0 4.1 4 0 0 4 4 4 1 PAS domain MCM2_N PF12619.3 OAJ05980.1 - 0.1 12.5 1.4 0.24 11.3 0.9 1.5 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 HATPase_c PF02518.21 OAJ05981.1 - 3.1e-30 104.1 0.0 1.1e-29 102.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 OAJ05981.1 - 1.1e-24 86.6 0.0 4.3e-24 84.6 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 OAJ05981.1 - 3.9e-20 71.6 0.1 1.2e-19 69.9 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 OAJ05981.1 - 6.8e-18 64.9 0.0 1.3e-11 44.7 0.0 5.0 5 0 0 5 5 5 2 PAS domain PAS_4 PF08448.5 OAJ05981.1 - 8.9e-18 64.3 0.8 2.5e-07 30.6 0.0 5.2 5 0 0 5 5 5 4 PAS fold PAS_3 PF08447.6 OAJ05981.1 - 1.8e-17 63.1 1.1 5.2e-17 61.7 0.2 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 OAJ05981.1 - 1e-11 44.5 0.0 0.012 15.4 0.0 5.0 5 0 0 5 5 5 3 PAS fold HATPase_c_3 PF13589.1 OAJ05981.1 - 0.0007 19.2 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 OAJ05988.1 - 2.3e-46 158.0 0.0 7.7e-46 156.3 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ05988.1 - 1.6e-17 63.4 0.0 2.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ05988.1 - 0.00062 18.8 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF294_C PF10335.4 OAJ05988.1 - 0.0008 19.0 0.0 0.0024 17.5 0.0 1.9 1 0 0 1 1 1 1 Putative nucleotidyltransferase substrate binding domain RIO1 PF01163.17 OAJ05988.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF1970 PF09301.5 OAJ05988.1 - 0.18 11.8 2.5 0.36 10.8 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) FlxA PF14282.1 OAJ05990.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 FlxA-like protein GTP_EFTU PF00009.22 OAJ05991.1 - 1.3e-46 158.3 0.0 3e-46 157.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 OAJ05991.1 - 4.9e-23 81.1 0.4 1.6e-22 79.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 OAJ05991.1 - 5e-09 36.1 2.4 5.1e-09 36.1 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 OAJ05991.1 - 0.00013 21.9 0.0 0.00035 20.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.4 OAJ05991.1 - 0.37 9.4 22.1 0.52 8.9 15.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC27 PF09507.5 OAJ05991.1 - 1.7 7.7 31.3 3.3 6.8 21.7 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RRM_1 PF00076.17 OAJ05992.1 - 3.1e-29 100.4 0.2 3.1e-12 45.9 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ05992.1 - 5.9e-20 71.0 0.0 1.2e-09 38.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ05992.1 - 2.6e-15 56.0 0.0 9.8e-06 25.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.13 OAJ05993.1 - 4.4e-10 38.9 35.1 4.2e-08 32.6 24.3 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF605 PF04652.11 OAJ05993.1 - 0.31 10.3 1.7 0.35 10.2 1.2 1.1 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 OAJ05993.1 - 5.1 6.2 9.1 9.8 5.2 6.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cyto_heme_lyase PF01265.12 OAJ05994.1 - 5.2e-65 219.6 0.1 6.7e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PACT_coil_coil PF10495.4 OAJ05995.1 - 3.1e-12 46.2 1.5 9.7e-12 44.6 0.2 2.6 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Reo_sigmaC PF04582.7 OAJ05995.1 - 0.3 10.2 15.8 0.035 13.2 1.4 4.3 2 2 2 4 4 4 0 Reovirus sigma C capsid protein GAS PF13851.1 OAJ05995.1 - 0.47 9.6 80.3 0.21 10.7 13.9 4.4 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 OAJ05995.1 - 0.66 9.7 62.5 0.025 14.3 3.9 8.0 8 2 0 8 8 8 0 Homeobox associated leucine zipper DivIC PF04977.10 OAJ05995.1 - 0.76 9.3 72.4 0.5 9.8 2.3 8.1 4 3 3 7 7 7 0 Septum formation initiator Filament PF00038.16 OAJ05995.1 - 2.3 7.6 82.2 0.44 9.9 38.8 4.3 2 1 1 3 3 3 0 Intermediate filament protein KLRAQ PF10205.4 OAJ05995.1 - 10 6.2 69.8 0.05 13.6 9.1 6.9 2 1 5 7 7 7 0 Predicted coiled-coil domain-containing protein Amidinotransf PF02274.12 OAJ05997.1 - 5.4e-20 71.6 0.0 2.3e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 Amidinotransferase PQ-loop PF04193.9 OAJ05998.1 - 1.6e-13 50.0 4.7 2e-12 46.4 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat Alpha_GJ PF03229.8 OAJ05998.1 - 0.53 10.6 5.3 1.4 9.2 0.7 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J AA_permease PF00324.16 OAJ05999.1 - 8.4e-63 212.3 32.6 1.1e-62 211.9 22.6 1.2 1 0 0 1 1 1 1 Amino acid permease Gar1 PF04410.9 OAJ06000.1 - 1.1e-36 125.6 2.8 1.3e-36 125.3 0.0 2.2 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region PIG-X PF08320.7 OAJ06002.1 - 1e-13 51.0 0.0 0.00014 21.2 0.0 3.5 3 1 0 3 3 3 3 PIG-X / PBN1 Med22 PF06179.7 OAJ06003.1 - 2.6e-14 53.1 0.1 4.2e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DEAD PF00270.24 OAJ06004.1 - 2.6e-47 160.4 0.0 7.1e-47 159.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ06004.1 - 1.7e-22 79.0 0.0 4e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 OAJ06004.1 - 2.9e-22 77.9 0.4 6.4e-22 76.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SNF2_N PF00176.18 OAJ06004.1 - 0.0018 17.1 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 OAJ06004.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 OAJ06004.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain HTH_40 PF14493.1 OAJ06004.1 - 0.046 13.9 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.11 OAJ06006.1 - 2.1e-37 128.6 34.0 2.1e-37 128.6 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06006.1 - 2.8e-07 29.5 14.7 2.8e-07 29.5 10.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter vWA-TerF-like PF10138.4 OAJ06007.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.5 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA PF00092.23 OAJ06007.1 - 0.0038 16.9 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF533 PF04391.7 OAJ06007.1 - 2.2 7.6 6.7 0.5 9.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) AAA PF00004.24 OAJ06008.1 - 8.7e-20 71.2 0.1 1.8e-09 37.8 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ06008.1 - 3e-11 43.2 1.6 3.8e-10 39.6 1.1 2.2 1 1 0 1 1 1 1 BCS1 N terminal AAA_19 PF13245.1 OAJ06008.1 - 0.0044 16.7 0.0 0.022 14.5 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 OAJ06008.1 - 0.0064 16.1 0.1 0.028 13.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 OAJ06008.1 - 0.0075 16.4 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ06008.1 - 0.012 16.4 0.3 0.041 14.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 OAJ06008.1 - 0.021 14.7 1.0 0.16 11.9 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain RuvB_N PF05496.7 OAJ06008.1 - 0.048 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 OAJ06008.1 - 0.072 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Brix PF04427.13 OAJ06010.1 - 6.3e-21 74.9 0.0 1.5e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Brix domain RNA_pol_3_Rpc31 PF11705.3 OAJ06010.1 - 0.45 10.4 38.2 0.78 9.6 26.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Usp PF00582.21 OAJ06010.1 - 0.79 9.9 0.0 0.79 9.9 0.0 2.3 3 0 0 3 3 3 0 Universal stress protein family Nop14 PF04147.7 OAJ06010.1 - 1.4 6.7 32.1 1.8 6.3 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 OAJ06010.1 - 2.6 7.2 31.6 0.16 11.1 18.5 1.6 2 0 0 2 2 2 0 SDA1 PPP4R2 PF09184.6 OAJ06010.1 - 6 6.3 24.5 10 5.5 17.0 1.3 1 0 0 1 1 1 0 PPP4R2 WD40 PF00400.27 OAJ06011.1 - 2.7e-26 90.4 6.9 1.3e-06 28.0 0.3 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 OAJ06011.1 - 0.094 10.8 0.0 0.18 9.9 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Glypican PF01153.14 OAJ06011.1 - 0.52 8.8 4.6 0.78 8.2 3.2 1.1 1 0 0 1 1 1 0 Glypican Sporozoite_P67 PF05642.6 OAJ06011.1 - 1.3 6.7 10.4 4.9 4.9 0.0 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen WD40 PF00400.27 OAJ06012.1 - 4.4e-51 169.0 12.0 1.2e-10 40.8 0.0 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Adaptin_N PF01602.15 OAJ06013.1 - 4.5e-102 342.0 0.0 5.8e-102 341.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 OAJ06013.1 - 1.3e-52 177.6 0.0 2.5e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 OAJ06013.1 - 8.1e-14 51.6 5.0 0.0011 19.2 0.1 5.8 3 3 4 7 7 7 4 HEAT repeats HEAT PF02985.17 OAJ06013.1 - 8.5e-05 22.3 3.8 2.1 8.6 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.2 OAJ06013.1 - 0.052 13.4 3.2 13 5.6 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 OAJ06013.1 - 0.11 11.5 0.1 14 4.5 0.0 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_PBS PF03130.11 OAJ06013.1 - 0.49 11.0 6.7 22 5.8 0.0 5.2 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Zds_C PF08632.5 OAJ06014.1 - 4.1e-21 74.1 0.6 7.8e-21 73.2 0.4 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term YHS PF04945.8 OAJ06014.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 YHS domain MOZ_SAS PF01853.13 OAJ06014.1 - 0.13 11.4 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 MOZ/SAS family DUF1935 PF09149.5 OAJ06015.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Nucleopor_Nup85 PF07575.8 OAJ06016.1 - 3.3e-70 236.9 0.0 5.4e-38 130.5 0.0 2.3 2 1 0 2 2 2 2 Nup85 Nucleoporin Spt5_N PF11942.3 OAJ06016.1 - 3.8 8.1 27.5 0.16 12.6 2.0 3.5 3 1 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF1640 PF07798.6 OAJ06017.1 - 2.5e-65 219.8 2.3 3.1e-65 219.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2077 PF09850.4 OAJ06017.1 - 0.11 11.9 1.0 2.4 7.5 0.0 2.7 2 2 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) HALZ PF02183.13 OAJ06017.1 - 0.22 11.2 1.8 1.5 8.6 1.2 2.4 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 OAJ06017.1 - 0.66 9.9 3.0 8.1 6.4 0.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Glyco_hydro_16 PF00722.16 OAJ06018.1 - 3.5e-06 26.4 0.0 6.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RXT2_N PF08595.6 OAJ06019.1 - 6.1 6.6 4.9 7.7 6.3 1.0 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Peptidase_M22 PF00814.20 OAJ06021.1 - 7.2e-66 222.4 0.2 1e-65 221.9 0.1 1.2 1 0 0 1 1 1 1 Glycoprotease family zf-RING_2 PF13639.1 OAJ06022.1 - 0.0021 17.8 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ06022.1 - 0.0041 16.7 0.5 0.0077 15.9 0.0 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ06022.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger MRG PF05712.8 OAJ06023.1 - 3.1e-54 182.8 0.0 5.2e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 OAJ06023.1 - 6e-09 35.4 0.0 1.8e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain IER PF05760.7 OAJ06023.1 - 0.9 9.4 7.6 1.7 8.5 5.2 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) HMA PF00403.21 OAJ06024.1 - 4.7e-17 61.8 0.6 5.5e-17 61.6 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Alba PF01918.16 OAJ06024.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Alba Gp37 PF09646.5 OAJ06024.1 - 0.087 12.2 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Gp37 protein Ribosomal_L28e PF01778.12 OAJ06025.1 - 7.2e-27 94.1 0.7 2.1e-26 92.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 OAJ06025.1 - 1e-20 73.6 24.4 1e-20 73.6 16.9 3.4 2 1 1 3 3 3 2 Mak16 protein C-terminal region Treacle PF03546.9 OAJ06025.1 - 0.0014 17.5 5.2 0.0023 16.7 3.6 1.3 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle PYC_OADA PF02436.13 OAJ06025.1 - 0.063 12.6 0.8 0.13 11.6 0.5 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain RhoGAP PF00620.22 OAJ06026.1 - 4.8e-38 130.1 0.3 1.1e-37 128.9 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 OAJ06026.1 - 2.1e-23 82.1 35.6 3.4e-10 39.8 4.7 5.0 5 0 0 5 5 5 4 LIM domain Dynein_light PF01221.13 OAJ06027.1 - 1.9e-35 120.6 0.1 2.5e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 dCMP_cyt_deam_2 PF08211.6 OAJ06027.1 - 0.056 13.4 0.2 0.071 13.1 0.1 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region P5CR_dimer PF14748.1 OAJ06029.1 - 1.1e-37 128.2 3.2 1.1e-37 128.2 2.2 2.1 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 OAJ06029.1 - 5.5e-13 49.1 0.0 1.1e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent dsrm PF00035.20 OAJ06030.1 - 1.4 9.5 3.8 8.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding motif BRF1 PF07741.8 OAJ06030.1 - 3 8.1 8.6 12 6.1 6.0 2.2 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 OAJ06031.1 - 1e-68 230.7 0.0 2e-68 229.8 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 OAJ06031.1 - 9.9e-16 57.4 3.3 9.9e-16 57.4 2.3 3.2 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 OAJ06031.1 - 2.4e-12 47.2 0.0 9.7e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.9 OAJ06031.1 - 0.49 9.5 6.6 4 6.6 4.1 2.5 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.2 OAJ06031.1 - 2.6 7.9 23.6 0.14 12.0 3.3 3.5 2 1 0 2 2 2 0 Double zinc ribbon DUF1610 PF07754.6 OAJ06031.1 - 5.1 7.3 16.7 0.45 10.6 0.7 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1610) IBR PF01485.16 OAJ06031.1 - 7.6 6.4 18.0 0.38 10.6 5.9 2.7 2 1 0 2 2 2 0 IBR domain Pkinase PF00069.20 OAJ06032.1 - 5.9e-71 238.6 0.0 7.4e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06032.1 - 1.3e-45 155.5 0.0 2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 OAJ06032.1 - 2.7e-21 75.7 0.1 6.6e-21 74.4 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 OAJ06032.1 - 0.0001 21.4 0.0 0.00015 20.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ06032.1 - 0.027 14.1 0.1 0.7 9.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 OAJ06032.1 - 0.03 13.5 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 OAJ06032.1 - 0.38 9.7 1.5 2.2 7.3 0.2 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.25 OAJ06034.1 - 1.4e-36 122.4 1.2 8.9e-11 41.0 0.0 5.6 5 1 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 OAJ06034.1 - 4.1e-36 123.1 0.0 1.4e-13 51.0 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ06034.1 - 7.4e-29 99.6 0.0 1.8e-13 50.5 0.0 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ06034.1 - 1.2e-27 93.1 0.0 4.5e-07 29.4 0.0 5.8 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 OAJ06034.1 - 8.2e-27 92.6 0.7 7.4e-11 41.9 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Cytochrom_C1 PF02167.10 OAJ06035.1 - 7.1e-88 293.9 0.0 9e-88 293.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 OAJ06035.1 - 0.00071 19.6 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 OAJ06035.1 - 0.043 14.6 0.1 0.15 12.8 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c CAP_GLY PF01302.20 OAJ06036.1 - 1.6e-26 91.8 1.1 2.4e-26 91.2 0.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 OAJ06036.1 - 6.5e-12 45.5 0.0 2.4e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Hist_deacetyl PF00850.14 OAJ06038.1 - 7.9e-52 176.4 0.0 1.2e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Sporozoite_P67 PF05642.6 OAJ06039.1 - 1.1 7.0 10.0 1.1 7.0 7.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.6 OAJ06039.1 - 8.3 4.2 27.9 14 3.5 19.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 AAA PF00004.24 OAJ06040.1 - 3.6e-18 66.0 0.0 8.3e-18 64.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 OAJ06040.1 - 7.9e-08 32.1 0.2 0.0046 16.5 0.0 2.3 2 0 0 2 2 2 2 BCS1 N terminal AAA_22 PF13401.1 OAJ06040.1 - 0.069 13.2 0.0 0.37 10.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain Transket_pyr PF02779.19 OAJ06042.1 - 2.3e-62 209.6 0.0 3.8e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 OAJ06042.1 - 8.8e-44 149.4 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component FHIPEP PF00771.15 OAJ06042.1 - 0.28 9.4 0.0 0.54 8.5 0.0 1.4 1 0 0 1 1 1 0 FHIPEP family DAHP_synth_1 PF00793.15 OAJ06043.1 - 4.5e-92 307.5 0.0 5.6e-92 307.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family DUF4042 PF13251.1 OAJ06044.1 - 1.8e-10 40.5 0.9 1.8e-10 40.5 0.6 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT PF02985.17 OAJ06044.1 - 3.9e-05 23.3 26.8 0.59 10.3 0.2 8.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 OAJ06044.1 - 0.063 13.5 38.0 0.1 12.8 4.6 6.6 4 2 3 7 7 7 0 HEAT repeats RasGEF_N_2 PF14663.1 OAJ06044.1 - 0.48 10.3 4.7 30 4.5 0.1 4.7 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MMtag PF10159.4 OAJ06045.1 - 1.9e-31 107.9 3.7 1.9e-31 107.9 2.6 3.3 3 2 1 4 4 4 1 Kinase phosphorylation protein RVT_1 PF00078.22 OAJ06052.1 - 1.8e-14 53.6 0.1 5.3e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 OAJ06052.1 - 0.0098 15.7 4.1 0.017 14.9 2.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 OAJ06052.1 - 0.012 16.1 0.0 0.077 13.5 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 OAJ06052.1 - 0.022 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.1 OAJ06052.1 - 0.029 13.8 0.8 0.063 12.7 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ06052.1 - 0.63 9.7 3.2 5.4 6.7 1.4 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-RING_2 PF13639.1 OAJ06053.1 - 5.3e-08 32.5 3.5 5.3e-08 32.5 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ06053.1 - 2.7e-06 27.3 8.6 1.2e-05 25.3 6.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 OAJ06053.1 - 0.00017 21.2 1.8 0.00017 21.2 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ06053.1 - 0.00082 19.3 2.0 0.00082 19.3 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ06053.1 - 0.0012 18.5 2.2 0.0012 18.5 1.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ06053.1 - 0.0021 17.7 2.2 0.0021 17.7 1.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ06053.1 - 0.024 14.4 1.1 0.024 14.4 0.8 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 OAJ06053.1 - 1.2 9.0 3.8 0.25 11.1 0.2 1.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Pyridox_oxidase PF01243.15 OAJ06054.1 - 0.00026 20.9 0.0 0.34 10.9 0.0 3.1 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 OAJ06054.1 - 0.14 12.3 0.0 1.3 9.1 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 OAJ06054.1 - 0.2 11.5 0.0 0.75 9.6 0.0 1.9 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Cofilin_ADF PF00241.15 OAJ06055.1 - 3.7e-11 43.0 0.0 2.4e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein KAP_NTPase PF07693.9 OAJ06056.1 - 2.2e-05 23.6 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 OAJ06056.1 - 8.7e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 OAJ06056.1 - 0.00033 21.4 0.1 0.0013 19.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ06056.1 - 0.00073 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 OAJ06056.1 - 0.0011 17.8 0.1 0.0021 16.8 0.1 1.4 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 OAJ06056.1 - 0.0072 16.6 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ06056.1 - 0.0082 15.8 0.3 0.021 14.5 0.2 1.7 1 1 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 OAJ06056.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 OAJ06056.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAJ06056.1 - 0.013 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 OAJ06056.1 - 0.015 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 OAJ06056.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAJ06056.1 - 0.036 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 OAJ06056.1 - 0.04 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 OAJ06056.1 - 0.049 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase VirE PF05272.6 OAJ06056.1 - 0.06 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E AAA_33 PF13671.1 OAJ06056.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 OAJ06056.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 OAJ06056.1 - 0.17 12.1 0.1 0.6 10.3 0.0 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) OTU PF02338.14 OAJ06057.1 - 1.4e-21 77.2 0.1 3.5e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAJ06057.1 - 0.0027 17.0 0.0 0.94 8.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain 3Beta_HSD PF01073.14 OAJ06058.1 - 9.5e-60 201.6 0.0 7.3e-56 188.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 OAJ06058.1 - 3.5e-25 88.8 0.0 5.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ06058.1 - 3.6e-12 46.6 0.0 1e-11 45.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ06058.1 - 1.4e-09 37.2 0.1 2.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 OAJ06058.1 - 2.3e-08 33.2 0.0 3.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 OAJ06058.1 - 1.2e-07 31.7 0.0 3.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ06058.1 - 0.00063 19.4 0.0 0.0023 17.6 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 OAJ06058.1 - 0.0022 16.9 0.1 0.0098 14.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 OAJ06058.1 - 0.0033 17.4 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain DNA_pol_B_exo1 PF03104.14 OAJ06058.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Strep_his_triad PF04270.8 OAJ06058.1 - 0.073 12.8 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Streptococcal histidine triad protein OST3_OST6 PF04756.8 OAJ06059.1 - 2.6e-17 62.8 3.5 2.6e-17 62.8 2.4 1.4 2 0 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 OAJ06059.1 - 0.00075 19.1 0.0 0.0015 18.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Pribosyltran PF00156.22 OAJ06060.1 - 1.1e-18 67.1 0.6 2.6e-18 65.9 0.4 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain End_beta_barrel PF12195.3 OAJ06060.1 - 0.15 11.7 0.3 0.52 10.0 0.2 1.9 1 1 1 2 2 2 0 Beta barrel domain of bacteriophage endosialidase YusW PF14039.1 OAJ06062.1 - 0.038 14.2 0.0 0.065 13.5 0.0 1.3 1 0 0 1 1 1 0 YusW-like protein Ribosomal_L4 PF00573.17 OAJ06063.1 - 1.1e-43 148.9 0.4 2.2e-43 147.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 OAJ06063.1 - 1.2e-27 95.5 1.3 3.7e-27 94.0 0.6 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Lipase_3 PF01764.20 OAJ06064.1 - 6.6e-23 80.8 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ06064.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LacAB_rpiB PF02502.13 OAJ06064.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Cnd1_N PF12922.2 OAJ06064.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term AhpC-TSA PF00578.16 OAJ06066.1 - 3e-20 72.1 0.0 3.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ06066.1 - 8.1e-14 51.3 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin DHHA1 PF02272.14 OAJ06066.1 - 0.0038 16.8 0.4 0.0093 15.6 0.3 1.7 1 0 0 1 1 1 1 DHHA1 domain PGBA_C PF15437.1 OAJ06066.1 - 0.44 10.7 4.5 0.8 9.8 3.1 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal rve PF00665.21 OAJ06067.1 - 9.9e-19 67.6 0.0 2.5e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ06067.1 - 0.0066 15.9 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HupF_HypC PF01455.13 OAJ06067.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 HupF/HypC family RVT_1 PF00078.22 OAJ06068.1 - 6.5e-17 61.6 0.0 1.3e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06068.1 - 9.3e-16 58.0 0.1 2.4e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06068.1 - 2.7e-06 27.7 0.0 4e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ06068.1 - 0.0065 16.2 0.1 0.019 14.7 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Reo_sigmaC PF04582.7 OAJ06068.1 - 0.018 14.2 3.2 0.039 13.1 2.2 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ATG16 PF08614.6 OAJ06068.1 - 0.048 13.4 0.2 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 OAJ06068.1 - 0.45 10.2 0.1 0.86 9.3 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II Fib_alpha PF08702.5 OAJ06068.1 - 1.1 9.4 0.1 1.8 8.6 0.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family WD40 PF00400.27 OAJ06069.1 - 3.7e-49 162.9 7.2 4.5e-09 35.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box-like PF12937.2 OAJ06069.1 - 2.3e-12 46.4 0.1 4.9e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ06069.1 - 4.7e-10 38.8 0.2 1.4e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 OAJ06069.1 - 1.7e-07 29.8 5.6 0.3 9.1 0.1 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40 PF00400.27 OAJ06070.1 - 3.6e-30 102.7 12.1 2.1e-08 33.7 0.4 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ06070.1 - 5.1e-07 28.2 2.4 0.0097 14.0 0.2 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ06070.1 - 0.027 13.2 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Nuf2 PF03800.9 OAJ06071.1 - 4.2e-33 114.3 0.0 1.3e-32 112.8 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family MukB PF04310.7 OAJ06071.1 - 0.1 11.9 0.1 0.26 10.6 0.1 1.6 1 0 0 1 1 1 0 MukB N-terminal Mnd1 PF03962.10 OAJ06071.1 - 1 9.0 41.0 0.21 11.2 6.1 4.0 1 1 3 4 4 4 0 Mnd1 family Imm3 PF14425.1 OAJ06071.1 - 3.9 7.4 9.6 0.52 10.2 0.3 3.5 2 2 1 3 3 3 0 Immunity protein Imm3 RNA_lig_T4_1 PF09511.5 OAJ06072.1 - 1.4e-77 260.1 0.0 2.2e-77 259.4 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 OAJ06072.1 - 1.6e-23 83.3 0.0 1.4e-14 54.3 0.0 2.6 2 1 0 2 2 2 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 OAJ06072.1 - 8.4e-22 77.6 0.0 2.4e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 OAJ06072.1 - 0.018 14.9 0.0 0.062 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ06072.1 - 0.046 12.9 0.5 1.1 8.3 0.4 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 MTHFR PF02219.12 OAJ06073.1 - 1.1e-110 369.2 0.0 1.4e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase 2-oxoacid_dh PF00198.18 OAJ06074.1 - 9.7e-80 267.1 0.1 1.3e-79 266.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 OAJ06074.1 - 1.3e-21 75.9 1.7 3e-21 74.8 1.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 OAJ06074.1 - 1e-17 63.4 0.1 2.5e-17 62.1 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 OAJ06074.1 - 0.00016 21.2 1.6 0.033 13.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like DNA_alkylation PF08713.6 OAJ06074.1 - 0.058 12.8 0.1 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme WD40 PF00400.27 OAJ06075.1 - 4.9e-40 134.0 4.7 1.9e-09 37.0 0.0 6.7 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ06075.1 - 1.7e-05 23.1 10.8 0.52 8.3 0.1 4.6 2 1 1 5 5 5 4 Nucleoporin Nup120/160 Aa_trans PF01490.13 OAJ06076.1 - 5.8e-86 288.5 5.6 7.3e-86 288.1 3.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YfhO PF09586.5 OAJ06076.1 - 2.1 6.2 6.4 0.51 8.3 1.9 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO MFS_1 PF07690.11 OAJ06077.1 - 9.8e-28 96.8 28.8 9.8e-28 96.8 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Helicase_C PF00271.26 OAJ06078.1 - 1.3e-17 63.4 0.0 2.7e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3246 PF11596.3 OAJ06078.1 - 0.0057 15.9 1.8 0.0057 15.9 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) Helicase_C_2 PF13307.1 OAJ06078.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Cyclin PF08613.6 OAJ06079.1 - 8.3e-28 97.6 0.1 1.1e-27 97.2 0.1 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 OAJ06079.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sec7_N PF12783.2 OAJ06080.1 - 9.2e-29 100.0 1.0 6.3e-28 97.2 0.0 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 OAJ06080.1 - 0.0011 18.3 0.0 0.014 14.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) PHD PF00628.24 OAJ06081.1 - 1.2e-10 40.8 8.4 2.4e-10 39.9 5.8 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 OAJ06081.1 - 0.00049 19.6 0.1 0.00049 19.6 0.0 2.3 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain UPF0184 PF03670.8 OAJ06081.1 - 0.032 14.4 0.8 0.032 14.4 0.6 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) PHD_2 PF13831.1 OAJ06081.1 - 0.11 11.8 2.4 0.2 10.9 1.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 OAJ06082.1 - 9e-33 112.5 5.3 9e-33 112.5 3.7 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 OAJ06082.1 - 6.2e-24 83.9 4.1 6.2e-24 83.9 2.8 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 OAJ06082.1 - 1.9e-22 80.2 0.8 1.9e-22 80.2 0.6 4.1 4 0 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.20 OAJ06082.1 - 4.5e-22 77.7 0.3 1e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 OAJ06082.1 - 3.2e-13 48.7 2.1 3.2e-13 48.7 1.4 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 OAJ06082.1 - 1.2e-08 34.5 8.9 1.2e-08 34.5 6.2 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.12 OAJ06082.1 - 3.7e-08 33.4 0.1 3.7e-07 30.2 0.0 2.6 2 0 0 2 2 2 1 PWWP domain Serglycin PF04360.7 OAJ06082.1 - 0.025 14.2 1.0 0.071 12.8 0.7 1.7 1 0 0 1 1 1 0 Serglycin C1_1 PF00130.17 OAJ06082.1 - 3 7.6 17.9 0.17 11.6 1.2 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nop14 PF04147.7 OAJ06082.1 - 3.3 5.4 30.8 6.2 4.6 21.3 1.4 1 0 0 1 1 1 0 Nop14-like family 4HBT PF03061.17 OAJ06083.1 - 5e-10 39.3 0.0 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily MaoC_dehydratas PF01575.14 OAJ06083.1 - 0.0067 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain DnaJ PF00226.26 OAJ06084.1 - 2.7e-27 94.2 1.8 4e-27 93.7 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 OAJ06084.1 - 6.2e-09 35.6 0.0 1e-05 25.3 0.0 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain RPT PF13446.1 OAJ06084.1 - 0.077 12.4 0.3 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 A repeated domain in UCH-protein AAA PF00004.24 OAJ06085.1 - 1.9e-47 160.7 0.0 1e-41 142.2 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ06085.1 - 3.5e-07 30.3 0.1 1.7e-05 24.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 OAJ06085.1 - 2.3e-05 24.3 0.0 6.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 OAJ06085.1 - 5.3e-05 23.2 0.0 0.077 13.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 OAJ06085.1 - 8.5e-05 22.0 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 OAJ06085.1 - 9.5e-05 22.5 0.2 0.01 15.9 0.0 3.4 3 1 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 OAJ06085.1 - 0.00066 18.8 0.4 0.21 10.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 OAJ06085.1 - 0.00075 19.1 0.0 0.004 16.8 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 OAJ06085.1 - 0.0019 17.9 0.0 0.0086 15.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 OAJ06085.1 - 0.0038 16.7 0.5 0.97 8.8 0.0 3.3 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_17 PF13207.1 OAJ06085.1 - 0.0058 17.4 0.0 0.031 15.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ06085.1 - 0.0068 15.8 0.7 0.037 13.4 0.1 2.6 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 OAJ06085.1 - 0.014 15.2 1.1 0.027 14.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 OAJ06085.1 - 0.024 14.9 1.6 0.041 14.1 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_14 PF13173.1 OAJ06085.1 - 0.033 14.0 0.0 0.097 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 OAJ06085.1 - 0.053 13.8 0.1 0.26 11.5 0.0 2.2 2 0 0 2 2 1 0 ABC transporter Bromodomain PF00439.20 OAJ06085.1 - 0.053 13.4 0.4 0.14 12.1 0.1 1.8 2 0 0 2 2 1 0 Bromodomain RNA_helicase PF00910.17 OAJ06085.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 OAJ06085.1 - 0.064 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Torsin PF06309.6 OAJ06085.1 - 0.11 12.4 0.1 0.55 10.1 0.0 2.1 3 0 0 3 3 3 0 Torsin PhoH PF02562.11 OAJ06085.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 OAJ06085.1 - 0.14 11.7 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Trp_DMAT PF11991.3 OAJ06086.1 - 6.6e-61 206.5 0.0 1.1e-60 205.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase SCP2_2 PF13530.1 OAJ06086.1 - 0.0016 17.9 0.1 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain DUF4632 PF15451.1 OAJ06086.1 - 0.076 12.9 0.2 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Pkinase PF00069.20 OAJ06087.1 - 2.6e-68 229.9 0.0 4.1e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06087.1 - 1.5e-48 165.1 0.0 2.5e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06087.1 - 2e-05 23.7 0.0 6.1e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ06087.1 - 0.025 14.2 0.0 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family RTTN_N PF14726.1 OAJ06087.1 - 0.065 13.8 2.2 0.18 12.4 0.2 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning ZZ PF00569.12 OAJ06089.1 - 2.4e-09 36.6 63.1 3.9e-05 23.0 1.8 6.3 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 OAJ06089.1 - 4.4e-05 23.0 0.1 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Peptidase_C97 PF05903.9 OAJ06090.1 - 3.6e-39 133.9 0.0 6.1e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain SRR1 PF07985.7 OAJ06090.1 - 2.1e-11 43.5 0.1 5.4e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 SRR1 MutL_C PF08676.6 OAJ06091.1 - 2.3e-21 75.9 0.3 9.2e-21 73.9 0.1 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 OAJ06091.1 - 7.1e-16 57.7 0.0 1.8e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 OAJ06091.1 - 4.1e-13 49.1 0.0 1.9e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 OAJ06091.1 - 4.3e-13 48.9 0.2 1e-11 44.5 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldo_ket_red PF00248.16 OAJ06092.1 - 1.6e-50 171.5 0.0 2e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.23 OAJ06095.1 - 6.2e-35 120.3 0.1 3.2e-34 118.0 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ06095.1 - 4.1e-25 88.1 0.0 6.2e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 OAJ06095.1 - 1.5e-07 31.1 0.0 8.2e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 OAJ06095.1 - 0.0001 22.4 0.1 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Aldedh PF00171.17 OAJ06099.1 - 6.6e-27 93.9 0.0 7.4e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Beta_elim_lyase PF01212.16 OAJ06100.1 - 6.4e-60 202.7 0.0 8.9e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 OAJ06100.1 - 0.00043 19.4 0.0 0.00071 18.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 OAJ06100.1 - 0.046 12.6 0.0 0.84 8.5 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II GATA PF00320.22 OAJ06102.1 - 1.9e-15 55.8 6.5 4.3e-15 54.7 4.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 OAJ06102.1 - 0.0031 17.5 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 OAJ06102.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.1 OAJ06102.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain bZIP_1 PF00170.16 OAJ06103.1 - 2.7e-08 33.6 6.2 4.2e-06 26.6 2.2 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 OAJ06103.1 - 1.9e-07 30.7 4.3 4.8e-07 29.4 3.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper SDA1 PF05285.7 OAJ06103.1 - 9.3 5.4 19.4 0.12 11.6 7.3 2.0 2 0 0 2 2 2 0 SDA1 DUF515 PF04415.7 OAJ06104.1 - 0.054 11.7 11.2 0.071 11.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) adh_short PF00106.20 OAJ06105.1 - 1.4e-22 80.3 0.3 7.1e-22 78.0 0.1 2.2 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ06105.1 - 8.9e-17 61.6 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ06105.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 OAJ06105.1 - 0.059 13.1 2.7 1.8 8.3 0.1 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2828 PF11443.3 OAJ06106.1 - 2.5e-141 471.5 0.0 2.9e-141 471.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) PBP1_TM PF14812.1 OAJ06106.1 - 4.9 7.5 7.1 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vps39_1 PF10366.4 OAJ06107.1 - 2.9e-29 101.2 0.2 9.9e-29 99.5 0.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 OAJ06107.1 - 2.1e-22 79.3 0.8 4.5e-22 78.2 0.2 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 OAJ06107.1 - 3.4e-16 59.4 0.0 1.8e-05 24.3 0.0 3.5 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.15 OAJ06107.1 - 3.3e-08 33.2 5.0 2.3e-05 24.0 0.1 2.7 3 0 0 3 3 3 2 Region in Clathrin and VPS Apc3 PF12895.2 OAJ06107.1 - 0.014 15.5 2.2 0.31 11.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT PF02985.17 OAJ06109.1 - 2.2e-36 120.6 25.2 0.0024 17.7 0.1 13.7 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 OAJ06109.1 - 2.8e-32 110.8 6.9 1.8e-08 34.5 0.0 6.7 2 2 3 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 OAJ06109.1 - 4.5e-10 39.7 25.4 0.056 13.9 0.0 8.8 8 2 2 10 10 10 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 OAJ06109.1 - 6.7e-10 39.2 1.0 0.11 12.9 0.1 6.7 4 2 5 9 9 9 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 OAJ06109.1 - 0.00033 19.1 8.9 0.013 13.8 0.4 4.5 4 1 1 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 OAJ06109.1 - 0.00062 19.1 2.4 0.036 13.4 0.1 4.3 1 1 2 5 5 5 1 CLASP N terminal DUF3554 PF12074.3 OAJ06109.1 - 0.0013 18.1 0.0 0.93 8.8 0.0 3.1 2 2 1 3 3 3 1 Domain of unknown function (DUF3554) Arm PF00514.18 OAJ06109.1 - 0.15 11.9 5.1 7 6.6 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat S-methyl_trans PF02574.11 OAJ06110.1 - 3.8e-38 131.4 0.0 9.5e-34 117.0 0.0 2.8 2 1 0 2 2 2 2 Homocysteine S-methyltransferase DnaJ PF00226.26 OAJ06111.1 - 4.6e-22 77.5 0.3 9.1e-22 76.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 OAJ06111.1 - 0.16 11.6 0.9 0.33 10.6 0.6 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 OAJ06111.1 - 1 9.5 9.7 0.27 11.3 4.2 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RRM_1 PF00076.17 OAJ06112.1 - 2.4e-13 49.5 0.0 2.5e-06 27.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06112.1 - 5.9e-11 42.1 0.0 0.00014 21.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAJ06112.1 - 0.22 9.4 46.1 0.015 13.2 19.3 2.2 2 0 0 2 2 2 0 Nop14-like family SAPS PF04499.10 OAJ06112.1 - 2.2 6.8 21.6 0.17 10.4 5.8 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 OAJ06112.1 - 3.1 6.0 9.5 3 6.0 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein AAA PF00004.24 OAJ06113.1 - 1.4e-41 141.7 0.0 3e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ06113.1 - 7.5e-06 26.1 0.0 0.00058 20.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 OAJ06113.1 - 1.2e-05 25.0 0.0 5.8e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ06113.1 - 7.3e-05 22.8 0.0 0.00028 20.9 0.0 1.9 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 OAJ06113.1 - 0.00021 21.2 0.0 0.00082 19.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 OAJ06113.1 - 0.00093 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 OAJ06113.1 - 0.0023 18.7 0.6 0.0053 17.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ06113.1 - 0.0031 17.2 0.1 0.0081 15.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 OAJ06113.1 - 0.0041 16.1 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 OAJ06113.1 - 0.011 14.8 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 OAJ06113.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ06113.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 OAJ06113.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 OAJ06113.1 - 0.023 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 OAJ06113.1 - 0.026 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 OAJ06113.1 - 0.029 14.0 0.1 5.9 6.5 0.0 2.5 2 1 1 3 3 2 0 Archaeal ATPase IstB_IS21 PF01695.12 OAJ06113.1 - 0.036 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 OAJ06113.1 - 0.04 13.0 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAJ06113.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 OAJ06113.1 - 0.052 12.2 0.0 0.092 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 OAJ06113.1 - 0.057 13.7 0.3 0.14 12.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 OAJ06113.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 OAJ06113.1 - 0.086 12.3 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 OAJ06113.1 - 0.1 12.0 0.2 0.34 10.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain SQS_PSY PF00494.14 OAJ06114.1 - 4e-37 127.9 0.0 7.9e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase Gtr1_RagA PF04670.7 OAJ06115.1 - 8.5e-36 123.2 0.0 1e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ06115.1 - 0.00028 21.3 0.0 0.001 19.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ06115.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 OAJ06115.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ06115.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 OAJ06115.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.16 OAJ06115.1 - 0.034 13.4 0.0 0.11 11.6 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_17 PF13207.1 OAJ06115.1 - 0.075 13.8 0.0 0.14 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC2_membrane PF01061.19 OAJ06116.1 - 1.5e-76 256.2 51.9 3.4e-40 137.4 12.9 2.2 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ06116.1 - 6.5e-35 120.3 0.0 4.2e-17 62.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ06116.1 - 1.3e-19 69.7 6.6 2.1e-17 62.6 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 OAJ06116.1 - 1.8e-06 27.8 0.0 5.1e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 OAJ06116.1 - 9e-06 25.2 0.1 0.0031 16.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ06116.1 - 1.3e-05 24.6 0.2 0.0077 15.7 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 OAJ06116.1 - 1.7e-05 24.1 0.0 0.0023 17.2 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 OAJ06116.1 - 2.9e-05 23.5 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAJ06116.1 - 4.2e-05 23.6 0.1 0.084 13.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 OAJ06116.1 - 6e-05 22.2 0.1 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 OAJ06116.1 - 0.00013 21.9 0.4 0.24 11.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 OAJ06116.1 - 0.00053 20.7 0.0 0.16 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ06116.1 - 0.0017 18.4 0.2 0.025 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 OAJ06116.1 - 0.0025 18.1 0.0 0.25 11.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 OAJ06116.1 - 0.0039 17.2 0.0 0.049 13.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 OAJ06116.1 - 0.018 14.5 0.4 1.4 8.3 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain AAA_28 PF13521.1 OAJ06116.1 - 0.025 14.5 0.1 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ06116.1 - 0.032 13.9 0.0 3.7 7.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 OAJ06116.1 - 0.037 13.6 0.4 3.1 7.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 OAJ06116.1 - 0.046 13.4 0.0 8 6.0 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 OAJ06116.1 - 0.048 13.9 0.4 0.52 10.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 OAJ06116.1 - 0.052 13.4 0.1 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 OAJ06116.1 - 0.062 12.7 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 OAJ06116.1 - 0.082 13.1 0.1 9.5 6.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 OAJ06116.1 - 0.16 11.5 0.1 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ06116.1 - 0.17 11.8 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.1 OAJ06116.1 - 0.42 9.6 0.0 0.94 8.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Thioredoxin PF00085.15 OAJ06117.1 - 1.2e-17 63.4 0.0 1.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 OAJ06117.1 - 0.0065 16.6 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 OAJ06117.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like tRNA-synt_1b PF00579.20 OAJ06118.1 - 9.8e-71 238.2 0.0 1.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Choline_kinase PF01633.15 OAJ06119.1 - 4.5e-34 117.8 0.0 2.7e-22 79.4 0.0 3.3 3 1 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.18 OAJ06119.1 - 0.00078 19.2 0.9 0.077 12.7 0.0 3.1 4 0 0 4 4 4 2 Phosphotransferase enzyme family Alk_phosphatase PF00245.15 OAJ06120.1 - 3e-88 296.3 0.1 3.7e-88 296.0 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase RCC1 PF00415.13 OAJ06121.1 - 6.1e-18 64.7 13.4 0.016 15.3 0.0 7.3 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 OAJ06121.1 - 5.4e-13 48.1 15.5 0.0076 15.8 0.1 8.1 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat Phage_integrase PF00589.17 OAJ06122.1 - 2.5e-05 24.0 0.0 0.00072 19.2 0.0 2.5 2 0 0 2 2 2 1 Phage integrase family OTU PF02338.14 OAJ06123.1 - 9.6e-06 26.1 0.0 5.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease zf-BED PF02892.10 OAJ06123.1 - 0.0019 17.8 0.2 0.0053 16.4 0.1 1.8 1 0 0 1 1 1 1 BED zinc finger Peptidase_M20 PF01546.23 OAJ06124.1 - 5.2e-29 101.1 0.0 8.9e-29 100.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ06124.1 - 9.8e-15 54.2 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain SLT PF01464.15 OAJ06125.1 - 0.00015 21.2 0.0 0.049 13.1 0.0 2.4 1 1 0 1 1 1 1 Transglycosylase SLT domain GCV_T PF01571.16 OAJ06126.1 - 5.9e-68 228.3 0.0 7.9e-68 227.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 OAJ06126.1 - 6.3e-24 83.8 0.0 1.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 OAJ06126.1 - 0.00015 21.6 0.0 0.00055 19.7 0.0 1.9 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family Thymidylate_kin PF02223.12 OAJ06127.1 - 3.6e-44 150.3 0.0 4.3e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 OAJ06127.1 - 3.4e-06 27.1 0.0 4.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 OAJ06127.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ06127.1 - 0.0061 16.4 0.1 0.11 12.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain PRK PF00485.13 OAJ06127.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 OAJ06127.1 - 0.11 12.4 0.1 0.99 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 OAJ06127.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 OAJ06128.1 - 4.5e-68 229.8 0.0 4.5e-53 180.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Ras PF00071.17 OAJ06129.1 - 4.7e-58 195.1 0.0 5.4e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ06129.1 - 3.6e-16 59.7 0.0 5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ06129.1 - 9.8e-07 28.1 0.0 1.8e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ06129.1 - 0.00043 19.7 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 OAJ06129.1 - 0.0038 16.4 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 OAJ06129.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 OAJ06129.1 - 0.13 11.7 0.0 11 5.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Asp PF00026.18 OAJ06130.1 - 2.6e-27 95.9 0.0 4.5e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ06130.1 - 0.0048 16.8 0.5 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ06130.1 - 0.015 15.7 0.0 0.92 10.0 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease TMEM154 PF15102.1 OAJ06130.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Arf PF00025.16 OAJ06131.1 - 3.5e-77 257.5 0.0 4e-77 257.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 OAJ06131.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 OAJ06131.1 - 2e-11 43.4 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 OAJ06131.1 - 2.6e-11 42.8 0.8 2.6e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 OAJ06131.1 - 4.3e-10 39.1 0.0 5.2e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 OAJ06131.1 - 1.3e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 OAJ06131.1 - 0.00013 21.9 0.0 0.00032 20.6 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 OAJ06131.1 - 0.00083 18.4 0.1 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 OAJ06131.1 - 0.013 14.9 0.0 0.098 12.0 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RNase_PH PF01138.16 OAJ06132.1 - 1.6e-23 83.4 0.0 2.7e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FixQ PF05545.6 OAJ06133.1 - 0.035 13.7 0.2 0.035 13.7 0.1 2.5 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ HCMV_UL139 PF12507.3 OAJ06133.1 - 0.087 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein Neisseria_TspB PF05616.8 OAJ06133.1 - 7.8 4.7 7.9 11 4.1 5.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PSK PF06404.7 OAJ06134.1 - 0.015 16.0 0.7 0.032 15.0 0.5 1.5 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DltD_N PF04915.7 OAJ06134.1 - 0.15 11.9 0.0 42 4.0 0.0 2.9 3 0 0 3 3 3 0 DltD N-terminal region CTP_transf_1 PF01148.15 OAJ06135.1 - 8.3e-67 225.5 28.0 6.3e-66 222.6 19.4 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family Complex1_LYR PF05347.10 OAJ06136.1 - 5.6e-08 32.4 1.0 7e-08 32.1 0.2 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ06136.1 - 2e-06 27.9 0.2 3.8e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 OAJ06136.1 - 9.2e-06 26.0 0.1 1.4e-05 25.4 0.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like A_deamin PF02137.13 OAJ06137.1 - 4.3e-55 187.4 0.0 5.5e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Methyltransf_31 PF13847.1 OAJ06138.1 - 8.1e-20 70.9 0.0 1.1e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ06138.1 - 6.8e-16 58.5 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ06138.1 - 5.9e-15 55.5 0.0 9.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ06138.1 - 1.8e-14 54.2 0.0 3.3e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ06138.1 - 7.9e-11 41.9 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ06138.1 - 2.4e-09 37.4 0.0 3.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ06138.1 - 3.9e-08 33.0 0.0 5.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 OAJ06138.1 - 4.9e-08 33.0 0.1 9.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ06138.1 - 6.9e-08 31.8 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 OAJ06138.1 - 8.4e-07 28.5 0.0 5.2e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 OAJ06138.1 - 4.6e-06 26.3 0.0 7.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 OAJ06138.1 - 5.5e-05 22.3 0.0 8.6e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.13 OAJ06138.1 - 0.00014 21.1 0.0 0.027 13.7 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 OAJ06138.1 - 0.00046 19.8 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 OAJ06138.1 - 0.0011 18.0 0.0 0.0022 17.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 OAJ06138.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 OAJ06138.1 - 0.014 14.9 0.1 0.025 14.1 0.0 1.4 2 0 0 2 2 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.7 OAJ06138.1 - 0.02 13.7 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.6 OAJ06138.1 - 0.023 13.4 0.0 0.041 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PrmA PF06325.8 OAJ06138.1 - 0.027 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 OAJ06138.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase SR-25 PF10500.4 OAJ06138.1 - 0.32 10.4 2.4 0.47 9.9 1.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNB PF00773.14 OAJ06140.1 - 3.2e-57 194.2 0.0 5.9e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 RNB domain DUF4366 PF14283.1 OAJ06141.1 - 0.0019 17.6 0.1 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Aldedh PF00171.17 OAJ06142.1 - 9.7e-131 436.2 0.0 1.2e-130 435.9 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MARVEL PF01284.18 OAJ06143.1 - 5.1e-05 23.1 8.2 9.5e-05 22.2 5.7 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.17 OAJ06143.1 - 0.027 13.4 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SIT PF15330.1 OAJ06143.1 - 2.8 8.1 0.0 2.8 8.1 0.0 3.0 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1771 PF08590.5 OAJ06144.1 - 3.9e-22 78.0 7.2 3.9e-22 78.0 5.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 OAJ06144.1 - 1.8e-16 60.0 0.1 1.8e-16 60.0 0.1 2.3 2 0 0 2 2 2 1 Smr domain RRF PF01765.14 OAJ06144.1 - 0.047 13.1 0.3 0.091 12.2 0.2 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Med15 PF09606.5 OAJ06144.1 - 0.93 7.6 21.9 0.99 7.5 15.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_L13 PF00572.13 OAJ06146.1 - 3.7e-25 88.4 0.2 6.9e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 Kua-UEV1_localn PF10520.4 OAJ06146.1 - 0.12 12.0 0.3 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Ribosomal_L32e PF01655.13 OAJ06147.1 - 3.2e-45 152.6 2.9 3.8e-45 152.4 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Glutaredoxin PF00462.19 OAJ06148.1 - 1.2e-19 70.0 0.0 1.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ06148.1 - 0.00054 20.1 0.1 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ06148.1 - 0.0014 18.8 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_9 PF14595.1 OAJ06148.1 - 0.004 16.7 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GST_N_2 PF13409.1 OAJ06148.1 - 0.0083 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_ribbon_2 PF12674.2 OAJ06148.1 - 0.015 15.5 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain Thioredoxin_7 PF13899.1 OAJ06148.1 - 0.033 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.1 OAJ06148.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MARVEL PF01284.18 OAJ06151.1 - 7.9e-05 22.5 20.2 0.00012 21.8 14.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF3784 PF12650.2 OAJ06151.1 - 0.01 15.7 3.2 0.01 15.7 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) COX4 PF02936.9 OAJ06152.1 - 2.6e-32 111.4 0.0 6.1e-32 110.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase subunit IV B12D PF06522.6 OAJ06152.1 - 0.3 10.7 1.3 0.77 9.5 0.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Abhydro_lipase PF04083.11 OAJ06153.1 - 9.9e-15 53.6 0.0 2.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 OAJ06153.1 - 1.5e-05 24.9 2.5 1.9e-05 24.6 0.8 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ06153.1 - 0.00045 19.8 0.1 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ06153.1 - 0.00064 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DnaJ PF00226.26 OAJ06154.1 - 7.7e-23 80.0 2.1 2.7e-22 78.2 0.1 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 OAJ06154.1 - 3.1e-22 77.9 15.7 2.9e-12 46.0 1.2 4.7 3 1 1 4 4 4 4 TPR repeat TPR_16 PF13432.1 OAJ06154.1 - 7.4e-20 71.0 22.4 4.6e-07 30.3 0.4 5.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ06154.1 - 9.6e-17 59.8 6.9 0.0007 19.0 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ06154.1 - 5.2e-15 54.0 20.0 0.014 15.2 0.7 7.5 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ06154.1 - 1.6e-14 53.9 21.2 1.1e-05 25.6 0.1 5.6 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ06154.1 - 1.3e-13 49.9 0.3 0.0054 16.8 0.0 4.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ06154.1 - 1.9e-12 46.6 21.9 0.025 15.1 0.1 6.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ06154.1 - 3.8e-12 45.8 12.6 1.8e-05 24.4 0.4 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 OAJ06154.1 - 7.1e-09 35.6 4.4 0.00036 20.5 0.1 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 OAJ06154.1 - 1e-06 28.0 6.0 0.74 9.7 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ06154.1 - 0.00037 20.0 5.8 0.98 9.3 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ06154.1 - 0.0036 17.2 16.2 0.15 12.0 0.2 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ06154.1 - 0.017 15.2 17.1 0.078 13.0 0.2 5.1 3 1 3 6 6 6 0 Tetratricopeptide repeat IF-2B PF01008.12 OAJ06154.1 - 0.03 13.3 0.6 0.054 12.4 0.4 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family Fis1_TPR_C PF14853.1 OAJ06154.1 - 0.12 12.2 5.4 0.38 10.6 0.0 4.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 OAJ06154.1 - 0.35 11.1 18.3 0.071 13.4 0.7 4.3 3 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 OAJ06154.1 - 0.48 11.0 15.8 6.6 7.4 0.0 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.6 OAJ06154.1 - 4.3 7.8 7.4 1.7 9.1 0.1 3.7 4 0 0 4 4 3 0 Cytochrome b562 ABC2_membrane PF01061.19 OAJ06155.1 - 1.4e-83 279.2 55.1 7e-43 146.2 16.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ06155.1 - 3e-40 137.6 0.0 2.7e-19 69.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 OAJ06155.1 - 1.8e-21 75.7 7.1 1.9e-19 69.1 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 OAJ06155.1 - 8.3e-08 32.2 0.1 1.8e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal SMC_N PF02463.14 OAJ06155.1 - 2.8e-07 30.0 0.0 5.3e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 OAJ06155.1 - 1.3e-06 27.9 0.1 0.0032 16.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 OAJ06155.1 - 2.4e-06 28.3 0.0 0.015 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 OAJ06155.1 - 6.6e-06 26.0 2.0 0.079 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.2 OAJ06155.1 - 6.9e-06 25.3 48.4 3.1e-05 23.1 12.1 3.3 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_29 PF13555.1 OAJ06155.1 - 1.8e-05 24.1 0.5 0.0092 15.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 OAJ06155.1 - 0.00012 21.6 0.0 0.0096 15.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 OAJ06155.1 - 0.00018 21.6 0.0 0.43 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 OAJ06155.1 - 0.00019 21.5 0.0 0.032 14.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 OAJ06155.1 - 0.00021 20.5 0.0 0.0086 15.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 OAJ06155.1 - 0.0012 18.8 3.7 0.038 13.9 0.2 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 OAJ06155.1 - 0.0049 17.1 3.8 0.27 11.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 OAJ06155.1 - 0.01 15.5 0.2 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 OAJ06155.1 - 0.013 15.2 0.3 2.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain DUF1825 PF08855.5 OAJ06155.1 - 0.019 14.9 0.4 9.1 6.3 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF1825) FtsK_SpoIIIE PF01580.13 OAJ06155.1 - 0.022 14.2 0.1 1.2 8.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 OAJ06155.1 - 0.028 14.0 0.4 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 OAJ06155.1 - 0.032 14.1 0.1 0.098 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 OAJ06155.1 - 0.045 13.3 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 OAJ06155.1 - 0.07 13.0 0.0 14 5.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 OAJ06155.1 - 0.081 12.3 0.5 5.3 6.3 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain RNA_helicase PF00910.17 OAJ06155.1 - 0.082 13.0 0.0 14 5.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 OAJ06155.1 - 0.094 12.9 0.0 22 5.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 OAJ06155.1 - 0.098 11.6 0.1 2 7.3 0.0 2.7 4 0 0 4 4 4 0 AAA ATPase domain T2SE PF00437.15 OAJ06155.1 - 0.4 9.5 0.2 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 OAJ06155.1 - 0.56 10.5 2.6 0.56 10.5 0.0 2.3 3 0 0 3 3 1 0 AAA domain SurE PF01975.12 OAJ06156.1 - 7.8e-34 116.7 0.2 1.8e-33 115.5 0.0 1.7 1 1 1 2 2 2 1 Survival protein SurE L51_S25_CI-B8 PF05047.11 OAJ06157.1 - 2.3e-10 40.0 0.0 2.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2404 PF10296.4 OAJ06158.1 - 2.4e-08 34.0 0.0 6e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DNA_pol_B PF00136.16 OAJ06159.1 - 4.8e-89 299.2 0.0 6.8e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 OAJ06159.1 - 7.5e-23 80.8 0.0 4.8e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 OAJ06159.1 - 3.4e-11 42.9 5.7 6.5e-11 42.0 3.9 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RPE65 PF03055.10 OAJ06167.1 - 1.3e-105 353.8 0.0 1.7e-105 353.3 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein BLVR PF06375.6 OAJ06168.1 - 0.22 11.3 6.0 0.12 12.1 2.6 1.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) BRF1 PF07741.8 OAJ06168.1 - 0.32 11.2 6.2 0.36 11.0 2.6 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain GCR1_C PF12550.3 OAJ06169.1 - 1e-19 70.1 1.3 1.7e-19 69.4 0.9 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes YPEB PF14620.1 OAJ06169.1 - 0.072 12.0 1.6 0.12 11.4 0.8 1.5 1 1 0 1 1 1 0 YpeB sporulation HTH_37 PF13744.1 OAJ06169.1 - 0.22 11.3 1.2 1.3 8.9 0.7 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Acyltransferase PF01553.16 OAJ06170.1 - 4e-15 55.4 0.0 1.2e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase MOSC PF03473.12 OAJ06171.1 - 2.6e-11 43.1 0.0 7.5e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.14 OAJ06171.1 - 2.7e-10 39.5 0.0 3e-08 32.8 0.0 3.4 3 1 0 3 3 3 1 Aminotransferase class-V MOSC_N PF03476.11 OAJ06171.1 - 8.8e-09 35.1 0.1 3.1e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain Toxin_14 PF07829.6 OAJ06171.1 - 0.066 12.9 0.5 0.2 11.4 0.3 1.8 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein HSD3 PF15244.1 OAJ06171.1 - 0.26 10.4 0.1 0.47 9.6 0.1 1.3 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase GST_C PF00043.20 OAJ06172.1 - 2.4e-09 37.0 0.0 4.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ06172.1 - 6.1e-09 35.9 0.1 3.1e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 OAJ06172.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ06172.1 - 8.8e-07 28.8 0.0 2.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ06172.1 - 3.3e-06 26.8 0.0 7.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ06172.1 - 2.5e-05 24.6 0.0 4.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SKN1 PF03935.10 OAJ06173.1 - 1.8e-177 590.5 1.8 2.1e-177 590.3 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 OAJ06173.1 - 0.042 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Neurensin Bac_rhodopsin PF01036.13 OAJ06174.1 - 3.5e-50 170.3 18.2 4.6e-50 169.9 12.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arteri_Gl PF00951.13 OAJ06174.1 - 0.19 11.2 3.8 0.11 12.1 0.9 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF3810 PF12725.2 OAJ06174.1 - 1.4 7.7 5.4 0.13 11.1 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2754 PF10953.3 OAJ06174.1 - 1.5 8.9 5.9 5.1 7.2 4.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2754) Cation_efflux PF01545.16 OAJ06174.1 - 1.6 7.7 8.6 2.6 7.0 6.0 1.3 1 0 0 1 1 1 0 Cation efflux family AgrB PF04647.10 OAJ06174.1 - 2.3 7.2 8.3 0.22 10.5 2.2 1.9 2 0 0 2 2 2 0 Accessory gene regulator B DUF4131 PF13567.1 OAJ06174.1 - 8.9 5.6 11.9 4.4 6.6 1.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HTH_Tnp_Tc5 PF03221.11 OAJ06175.1 - 0.00056 19.6 0.2 0.0016 18.2 0.0 1.9 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF746 PF05344.6 OAJ06177.1 - 0.13 11.7 0.4 0.48 9.9 0.0 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF746) DDE_3 PF13358.1 OAJ06178.1 - 1.5e-31 109.1 0.0 3.6e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ06178.1 - 6e-10 39.2 0.0 2.6e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ06178.1 - 2.2e-09 37.9 0.7 1.1e-08 35.7 0.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain DDE_1 PF03184.14 OAJ06178.1 - 2.3e-06 26.9 0.0 4.2e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ06178.1 - 2.2e-05 23.8 0.1 7.2e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 OAJ06178.1 - 0.00016 21.6 0.1 0.0059 16.6 0.0 2.5 2 0 0 2 2 2 1 Transposase Arg_repressor PF01316.16 OAJ06178.1 - 0.0032 16.9 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Arginine repressor, DNA binding domain rve PF00665.21 OAJ06178.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF2293 PF10056.4 OAJ06178.1 - 0.021 14.8 0.1 0.062 13.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Ammonium_transp PF00909.16 OAJ06180.1 - 1.2e-104 349.9 31.0 1.6e-104 349.5 21.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YuiB PF14068.1 OAJ06180.1 - 0.38 11.1 7.1 0.18 12.1 2.8 2.1 2 0 0 2 2 2 0 Putative membrane protein YqzM PF14141.1 OAJ06180.1 - 6.9 6.5 7.1 0.23 11.2 0.2 2.1 2 0 0 2 2 2 0 YqzM-like protein Rootletin PF15035.1 OAJ06181.1 - 0.011 15.6 0.6 0.012 15.6 0.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion IFT20 PF14931.1 OAJ06181.1 - 0.19 11.5 1.9 0.37 10.7 1.3 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Secretin_N_2 PF07655.8 OAJ06181.1 - 0.23 11.8 3.8 0.31 11.4 2.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Spc42p PF11544.3 OAJ06181.1 - 1.9 8.4 10.1 0.077 12.9 1.6 2.4 2 1 0 2 2 2 0 Spindle pole body component Spc42p DUF2051 PF09738.4 OAJ06181.1 - 3 7.0 6.6 0.3 10.3 1.1 1.7 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) G_glu_transpept PF01019.16 OAJ06182.1 - 2.7e-140 468.2 0.1 3.1e-140 468.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RNase_P_p30 PF01876.11 OAJ06183.1 - 8.9e-33 112.6 0.0 1.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 CRAL_TRIO PF00650.15 OAJ06184.1 - 1e-22 80.3 0.0 1.4e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ06184.1 - 2.3e-07 30.8 0.0 6.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAJ06184.1 - 0.019 14.8 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain ETF PF01012.16 OAJ06185.1 - 1.9e-38 131.7 4.8 3.5e-38 130.9 3.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 OAJ06185.1 - 1.9e-35 120.3 1.7 3e-35 119.6 0.4 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain GxGYxYP PF14323.1 OAJ06185.1 - 0.1 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function bZIP_1 PF00170.16 OAJ06186.1 - 6.6e-07 29.1 4.6 1.3e-06 28.2 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ06186.1 - 0.0022 17.7 1.9 0.0053 16.5 1.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Alginate_lyase PF05426.7 OAJ06187.1 - 2.4e-49 168.1 5.3 9.1e-48 162.9 1.4 2.3 2 0 0 2 2 2 2 Alginate lyase Pil1 PF13805.1 OAJ06188.1 - 7.5e-05 22.0 1.7 7.5e-05 22.0 1.2 2.2 2 0 0 2 2 2 1 Eisosome component PIL1 AMP-binding PF00501.23 OAJ06189.1 - 5.2e-79 265.5 0.0 6.7e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06189.1 - 2.1e-07 31.7 0.0 7.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_6 PF13458.1 OAJ06189.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein AlaDh_PNT_N PF05222.10 OAJ06189.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain AMP-binding PF00501.23 OAJ06190.1 - 5.6e-79 265.4 0.0 7.1e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06190.1 - 1.3e-11 45.2 0.0 3.3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSase_L_D2 PF02786.12 OAJ06190.1 - 0.071 12.3 0.0 0.8 8.9 0.0 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain FA_hydroxylase PF04116.8 OAJ06191.1 - 6.9e-13 49.0 15.4 1e-12 48.4 7.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EBP50_C-term PF09007.6 OAJ06191.1 - 0.078 12.8 0.1 0.078 12.8 0.1 1.8 2 0 0 2 2 2 0 EBP50, C-terminal Na_Ca_ex PF01699.19 OAJ06192.1 - 2.2e-39 134.2 26.4 1.8e-21 76.2 5.4 2.9 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 OAJ06192.1 - 1.2 9.0 3.9 1.2 9.0 0.4 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) BTB_2 PF02214.17 OAJ06193.1 - 0.014 15.5 0.0 0.33 11.1 0.0 2.5 2 0 0 2 2 2 0 BTB/POZ domain Sporozoite_P67 PF05642.6 OAJ06193.1 - 2.9 5.6 5.1 0.17 9.7 0.1 1.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FHA PF00498.21 OAJ06194.1 - 3.7e-08 33.3 0.1 1.3e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 FHA domain Gti1_Pac2 PF09729.4 OAJ06195.1 - 4.2e-56 189.4 0.0 8.5e-56 188.4 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family AMP-binding PF00501.23 OAJ06196.1 - 3.4e-77 259.5 0.0 4.4e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06196.1 - 4.5e-11 43.5 0.0 1.2e-10 42.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIS_M PF07500.9 OAJ06197.1 - 1.9e-23 82.7 0.2 1.9e-23 82.7 0.1 2.0 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 OAJ06197.1 - 1.8e-18 65.8 7.3 2.8e-18 65.2 5.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 OAJ06197.1 - 9.1e-16 57.1 0.5 9.1e-16 57.1 0.3 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 OAJ06197.1 - 0.086 12.2 0.6 0.18 11.1 0.2 1.6 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF2347 PF09804.4 OAJ06198.1 - 5e-35 121.1 0.0 9.2e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 OAJ06198.1 - 0.00094 17.7 0.0 0.0016 17.0 0.0 1.3 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.7 OAJ06198.1 - 0.012 15.5 0.6 0.06 13.3 0.0 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SpoVIF PF14069.1 OAJ06198.1 - 0.023 14.3 0.1 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Stage VI sporulation protein F CDC45 PF02724.9 OAJ06198.1 - 0.12 10.3 0.3 0.18 9.8 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 OAJ06198.1 - 0.55 9.7 6.1 0.41 10.1 2.1 2.1 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 OAJ06198.1 - 2 7.5 4.7 3.4 6.8 3.3 1.3 1 0 0 1 1 1 0 NOA36 protein ATG22 PF11700.3 OAJ06199.1 - 2.9e-116 388.7 19.7 3.4e-116 388.5 13.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 OAJ06199.1 - 6.8e-07 28.3 33.2 0.0012 17.6 7.7 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Herpes_gE PF02480.11 OAJ06200.1 - 0.12 10.6 0.0 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RVT_1 PF00078.22 OAJ06201.1 - 2.4e-16 59.7 0.0 4.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06201.1 - 3.2e-14 53.0 0.0 7.4e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06201.1 - 0.0029 18.0 0.0 0.0077 16.7 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ06201.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease ASXH PF13919.1 OAJ06201.1 - 0.2 11.4 0.4 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 Asx homology domain Foamy_BEL PF03274.9 OAJ06201.1 - 0.42 9.7 0.0 0.74 9.0 0.0 1.3 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein Retrotrans_gag PF03732.12 OAJ06202.1 - 0.0073 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein Dimer_Tnp_hAT PF05699.9 OAJ06203.1 - 4.9e-13 48.5 0.0 9.6e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4102 PF13356.1 OAJ06203.1 - 0.16 11.8 0.6 0.66 9.9 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4102) Pkinase PF00069.20 OAJ06204.1 - 3e-40 138.0 0.0 4.9e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06204.1 - 8e-19 67.7 0.0 1.3e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06204.1 - 2.1e-07 30.2 0.0 3.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Myf5 PF12232.3 OAJ06204.1 - 2.7 8.6 15.5 0.43 11.2 6.7 2.4 2 0 0 2 2 2 0 Myogenic determination factor 5 Pkinase PF00069.20 OAJ06205.1 - 2.2e-72 243.3 0.0 2.9e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06205.1 - 3.4e-36 124.6 0.0 5.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06205.1 - 3.4e-06 26.2 0.0 5.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 OAJ06205.1 - 0.0077 15.5 0.1 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 OAJ06205.1 - 0.019 15.1 0.1 0.043 14.0 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) zf-BED PF02892.10 OAJ06206.1 - 0.021 14.6 1.4 0.052 13.3 1.0 1.7 1 0 0 1 1 1 0 BED zinc finger Bromodomain PF00439.20 OAJ06207.1 - 0.0066 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PLA2_B PF01735.13 OAJ06208.1 - 1.2e-13 50.0 0.0 1.5e-06 26.6 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain FHA PF00498.21 OAJ06209.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 FHA domain Syja_N PF02383.13 OAJ06212.1 - 6.5e-89 297.8 0.0 9.9e-89 297.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain LysM PF01476.15 OAJ06213.1 - 1.4e-13 50.5 0.1 4.6e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 LysM domain RskA PF10099.4 OAJ06213.1 - 0.1 12.3 2.2 0.15 11.7 1.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Apc4 PF12896.2 OAJ06214.1 - 1.2e-21 77.0 0.1 2.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 YCII PF03795.9 OAJ06215.1 - 0.0049 17.0 0.0 0.019 15.1 0.0 2.0 1 0 0 1 1 1 1 YCII-related domain DUF4544 PF15077.1 OAJ06215.1 - 1.2 8.5 3.6 2 7.8 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Mago_nashi PF02792.9 OAJ06216.1 - 3.7e-74 247.1 0.4 4.2e-74 246.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 OAJ06216.1 - 0.16 11.7 0.2 0.31 10.8 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) ER_lumen_recept PF00810.13 OAJ06217.1 - 2.2e-49 167.7 3.0 3e-49 167.3 2.1 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 OAJ06217.1 - 0.00076 18.9 10.9 0.0084 15.6 0.5 4.0 4 0 0 4 4 4 2 PQ loop repeat Phage_GPD PF05954.6 OAJ06218.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Phage_GP20 PF06810.6 OAJ06219.1 - 0.0036 16.7 4.4 0.0036 16.7 3.0 2.2 1 1 1 2 2 2 1 Phage minor structural protein GP20 DUF4200 PF13863.1 OAJ06219.1 - 0.0039 17.1 26.1 0.0048 16.8 10.5 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Spc7 PF08317.6 OAJ06219.1 - 0.0049 15.5 12.1 0.0063 15.2 8.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3584 PF12128.3 OAJ06219.1 - 0.015 12.6 14.6 0.02 12.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 OAJ06219.1 - 0.022 14.5 2.0 0.029 14.1 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.7 OAJ06219.1 - 0.026 14.2 23.0 0.097 12.4 4.5 2.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.8 OAJ06219.1 - 0.031 13.3 7.6 0.068 12.2 5.3 1.6 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.5 OAJ06219.1 - 0.035 14.2 4.2 0.049 13.7 2.6 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 OAJ06219.1 - 0.084 13.1 14.3 1 9.6 3.2 2.1 2 0 0 2 2 2 0 Spectrin repeat IncA PF04156.9 OAJ06219.1 - 0.088 12.3 22.8 0.35 10.4 7.0 2.0 1 1 1 2 2 2 0 IncA protein UxaC PF02614.9 OAJ06219.1 - 0.12 10.9 1.2 0.16 10.5 0.8 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Bacillus_HBL PF05791.6 OAJ06219.1 - 0.13 11.6 2.2 0.21 10.9 1.5 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.6 OAJ06219.1 - 0.13 12.0 18.5 0.33 10.7 4.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Sec2p PF06428.6 OAJ06219.1 - 0.14 12.0 16.0 0.25 11.2 10.7 1.8 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p KaiC PF06745.8 OAJ06219.1 - 0.14 11.2 0.9 0.18 10.8 0.6 1.2 1 0 0 1 1 1 0 KaiC TTKRSYEDQ PF10212.4 OAJ06219.1 - 0.16 10.8 3.5 0.19 10.6 2.5 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Filament PF00038.16 OAJ06219.1 - 0.19 11.1 19.6 0.26 10.6 7.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF3552 PF12072.3 OAJ06219.1 - 0.26 10.4 27.2 0.087 12.0 9.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF4407 PF14362.1 OAJ06219.1 - 0.28 10.1 15.1 0.33 9.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.1 OAJ06219.1 - 0.35 10.0 19.0 2.5 7.2 4.0 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 OAJ06219.1 - 0.4 9.0 11.0 0.56 8.5 7.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 OAJ06219.1 - 0.41 10.4 26.8 0.62 9.9 3.0 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 OAJ06219.1 - 0.46 10.8 14.7 0.3 11.4 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ERM PF00769.14 OAJ06219.1 - 0.48 9.9 26.6 0.47 9.9 16.2 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 OAJ06219.1 - 0.6 8.5 14.4 0.17 10.3 6.5 1.8 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.7 OAJ06219.1 - 0.67 9.7 8.0 1.5 8.6 0.5 2.1 2 0 0 2 2 2 0 Laminin Domain II CHASE3 PF05227.8 OAJ06219.1 - 0.68 9.6 13.3 1.2 8.8 8.7 1.8 1 1 1 2 2 2 0 CHASE3 domain DUF730 PF05325.6 OAJ06219.1 - 0.75 9.6 5.6 3.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Atg14 PF10186.4 OAJ06219.1 - 0.85 8.4 18.0 1.4 7.8 12.5 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 OAJ06219.1 - 1 8.3 27.4 0.15 11.1 8.7 2.2 1 1 1 2 2 2 0 Tropomyosin CENP-F_leu_zip PF10473.4 OAJ06219.1 - 1.1 9.0 23.3 2.6 7.9 16.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 OAJ06219.1 - 1.2 8.5 16.6 0.13 11.7 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Kinetocho_Slk19 PF12709.2 OAJ06219.1 - 1.3 9.1 11.8 2.5 8.2 1.0 2.6 1 1 1 2 2 2 0 Central kinetochore-associated STAT_alpha PF01017.15 OAJ06219.1 - 1.6 8.3 9.0 52 3.4 6.3 2.1 1 1 0 1 1 1 0 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.17 OAJ06219.1 - 1.8 8.6 20.1 0.81 9.7 3.2 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 OAJ06219.1 - 1.9 7.9 12.4 7.1 6.0 8.6 1.9 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like THOC7 PF05615.8 OAJ06219.1 - 2.9 8.1 16.6 8.6 6.6 11.5 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 SlyX PF04102.7 OAJ06219.1 - 2.9 8.3 10.9 5.2 7.5 0.9 2.9 1 1 3 4 4 4 0 SlyX APG6 PF04111.7 OAJ06219.1 - 3 6.8 20.4 0.16 10.9 8.9 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 OAJ06219.1 - 3 7.6 24.4 4.2 7.1 16.5 1.6 1 1 0 1 1 1 0 Tropomyosin like Synaptobrevin PF00957.16 OAJ06219.1 - 3.2 7.4 4.8 1.3 8.6 0.3 2.2 2 1 1 3 3 3 0 Synaptobrevin DUF479 PF04336.7 OAJ06219.1 - 3.2 7.8 5.1 10 6.2 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF479 HAUS-augmin3 PF14932.1 OAJ06219.1 - 3.9 6.5 13.5 5.2 6.1 9.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tho2 PF11262.3 OAJ06219.1 - 4.8 6.1 10.7 3.8 6.4 1.5 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BLOC1_2 PF10046.4 OAJ06219.1 - 4.8 7.3 8.0 1.1 9.4 1.0 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HR1 PF02185.11 OAJ06219.1 - 5.2 6.8 14.4 1.6 8.4 0.9 2.6 2 1 0 2 2 2 0 Hr1 repeat CENP-H PF05837.7 OAJ06219.1 - 5.3 7.2 12.4 1.4 9.1 5.8 1.9 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Apt1 PF10351.4 OAJ06219.1 - 5.4 5.7 11.9 0.2 10.4 0.6 2.0 1 1 1 2 2 2 0 Golgi-body localisation protein domain DUF2203 PF09969.4 OAJ06219.1 - 6.2 7.0 7.5 30 4.8 5.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.10 OAJ06219.1 - 6.5 6.3 18.1 5.1 6.6 2.7 2.8 1 1 1 3 3 3 0 Septum formation initiator Erp_C PF06780.6 OAJ06219.1 - 7.1 6.4 10.1 1.4 8.7 4.9 1.5 2 0 0 2 2 1 0 Erp protein C-terminus DivIVA PF05103.8 OAJ06219.1 - 7.5 6.6 17.1 4.5 7.3 8.3 2.2 1 1 1 2 2 2 0 DivIVA protein COG2 PF06148.6 OAJ06219.1 - 8.3 6.2 10.7 1.6 8.5 1.5 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AATF-Che1 PF13339.1 OAJ06219.1 - 8.3 6.5 10.7 17 5.5 7.4 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Occludin_ELL PF07303.8 OAJ06219.1 - 8.5 7.1 9.6 3.5 8.3 3.9 2.1 1 1 1 2 2 2 0 Occludin homology domain HAUS6_N PF14661.1 OAJ06219.1 - 8.7 5.6 15.7 2.9 7.1 4.2 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Fmp27_WPPW PF10359.4 OAJ06219.1 - 9 4.5 14.8 0.74 8.1 5.4 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FemAB PF02388.11 OAJ06219.1 - 9.1 4.8 10.7 23 3.5 7.2 1.8 1 1 0 1 1 1 0 FemAB family DUF724 PF05266.9 OAJ06219.1 - 9.5 5.7 19.0 3.3 7.3 9.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_2 PF07716.10 OAJ06219.1 - 9.9 6.0 16.4 0.16 11.8 2.3 3.2 2 1 1 3 3 3 0 Basic region leucine zipper G_glu_transpept PF01019.16 OAJ06220.1 - 3.5e-112 375.5 0.0 4.4e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HALZ PF02183.13 OAJ06224.1 - 0.00021 20.9 0.4 0.00021 20.9 0.2 1.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF4337 PF14235.1 OAJ06224.1 - 0.23 11.2 1.9 0.35 10.7 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2406 PF10295.4 OAJ06224.1 - 0.42 11.1 4.7 0.84 10.1 3.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein (DUF2406) DUF972 PF06156.8 OAJ06224.1 - 2.1 8.7 5.2 3.8 7.9 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 OAJ06224.1 - 5.1 6.6 6.2 6.2 6.3 3.1 1.9 1 1 1 2 2 2 0 Septum formation initiator Brr6_like_C_C PF10104.4 OAJ06225.1 - 0.0046 16.4 1.7 0.009 15.5 0.9 1.7 1 1 1 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain RVT_1 PF00078.22 OAJ06227.1 - 6.6e-17 61.5 0.0 1.2e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06227.1 - 6.9e-13 48.7 0.0 2.9e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06227.1 - 0.00043 20.7 0.1 0.0013 19.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ06227.1 - 0.04 13.7 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ06227.1 - 0.25 11.2 0.0 0.68 9.8 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease COPIIcoated_ERV PF07970.7 OAJ06228.1 - 3.5e-37 128.1 0.2 5.3e-37 127.5 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 OAJ06228.1 - 7.1e-23 80.4 0.0 1.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Aldo_ket_red PF00248.16 OAJ06229.1 - 7.8e-69 231.6 0.0 8.8e-69 231.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 OAJ06230.1 - 2.1e-10 40.2 0.0 2.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ06230.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding RVT_1 PF00078.22 OAJ06231.1 - 3.4e-18 65.7 0.0 6.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06231.1 - 5.9e-12 45.7 0.0 2.6e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 OAJ06231.1 - 0.0017 18.7 0.1 0.0074 16.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 OAJ06231.1 - 0.091 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Peptidase_M76 PF09768.4 OAJ06234.1 - 1.2e-48 164.8 0.0 2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M76 family Methyltransf_26 PF13659.1 OAJ06235.1 - 9.6e-13 48.1 0.0 2.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 OAJ06235.1 - 1e-12 47.9 0.0 3.8e-12 46.1 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 OAJ06235.1 - 4.2e-05 23.1 0.0 0.00053 19.5 0.0 2.5 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 OAJ06235.1 - 0.0036 16.4 0.0 0.012 14.7 0.0 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 OAJ06235.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Met_10 PF02475.11 OAJ06235.1 - 0.21 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF3506 PF12014.3 OAJ06236.1 - 9.6e-11 41.6 0.0 4.9e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 OAJ06236.1 - 2.9e-08 33.3 0.3 6.8e-08 32.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ06236.1 - 3.5e-06 26.5 0.1 9.2e-06 25.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 OAJ06236.1 - 0.68 10.3 2.0 0.77 10.1 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Mito_carr PF00153.22 OAJ06237.1 - 6.4e-64 211.7 3.3 4e-24 84.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein V4R PF02830.13 OAJ06237.1 - 0.2 11.5 0.6 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 V4R domain Tim17 PF02466.14 OAJ06237.1 - 2.8 7.9 7.4 2.9 7.9 0.2 3.2 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Tyrosinase PF00264.15 OAJ06239.1 - 3.2e-49 168.1 3.5 4.4e-49 167.6 2.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PPO1_DWL PF12142.3 OAJ06239.1 - 0.093 12.2 0.1 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Polyphenol oxidase middle domain RRM_1 PF00076.17 OAJ06241.1 - 1.1e-34 117.8 0.1 5.5e-17 61.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06241.1 - 1e-32 111.9 0.2 1.8e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06241.1 - 5.7e-11 42.1 0.1 7.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ06241.1 - 0.0079 16.0 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ06241.1 - 0.015 15.0 0.1 3.4 7.5 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Fungal_trans PF04082.13 OAJ06242.1 - 3.6e-18 65.3 0.9 3.6e-18 65.3 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ06242.1 - 1.2e-07 31.4 10.2 1.9e-07 30.8 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_C PF02984.14 OAJ06242.1 - 0.1 12.5 1.3 2.6 8.0 0.1 2.7 2 1 0 2 2 2 0 Cyclin, C-terminal domain GCIP PF13324.1 OAJ06242.1 - 4.8 6.3 6.6 9.1 5.4 4.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ALO PF04030.9 OAJ06243.1 - 1.1e-64 218.5 0.1 1.1e-54 185.7 0.0 2.4 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 OAJ06243.1 - 1.1e-18 66.9 0.0 2.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DUF3074 PF11274.3 OAJ06245.1 - 1.5e-41 142.0 0.0 2e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) RVT_1 PF00078.22 OAJ06246.1 - 0.0017 17.7 0.0 0.0061 15.9 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S17 PF00366.15 OAJ06247.1 - 2.6e-16 59.3 0.1 3.8e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 F_actin_bind PF08919.5 OAJ06247.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 F-actin binding UBA_4 PF14555.1 OAJ06249.1 - 1.3e-09 37.4 0.1 3.5e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.15 OAJ06249.1 - 0.33 10.6 13.6 0.82 9.4 0.9 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif zf-C2H2 PF00096.21 OAJ06250.1 - 2.4e-05 24.4 12.1 0.064 13.6 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ06250.1 - 5.7e-05 23.1 12.3 0.042 14.1 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 OAJ06250.1 - 0.00058 20.0 10.7 0.00068 19.8 0.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain CUE PF02845.11 OAJ06251.1 - 1.3e-08 34.1 0.0 2.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.6 OAJ06251.1 - 0.2 11.6 0.1 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Mur_ligase_M PF08245.7 OAJ06252.1 - 0.00045 20.3 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain AAA_12 PF13087.1 OAJ06253.1 - 8.4e-47 159.1 0.0 1.4e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ06253.1 - 1.3e-41 142.7 0.0 2.9e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ06253.1 - 8.1e-13 47.9 2.4 9.1e-12 44.5 1.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 OAJ06253.1 - 2.6e-09 36.9 0.4 4e-07 29.8 0.2 2.8 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 OAJ06253.1 - 0.00036 19.9 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 OAJ06253.1 - 0.00058 19.4 0.2 4.7 6.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 OAJ06253.1 - 0.049 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 OAJ06253.1 - 0.11 12.1 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 OAJ06253.1 - 0.29 10.0 0.6 1.3 7.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Vps35 PF03635.12 OAJ06254.1 - 0 1101.6 0.0 0 1101.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.17 OAJ06254.1 - 1.6e-20 72.4 0.0 3.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06254.1 - 8.2e-15 54.5 0.0 2.3e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06254.1 - 5.9e-12 45.2 0.0 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAJ06254.1 - 1.2 7.0 1.4 1.9 6.3 1.0 1.3 1 0 0 1 1 1 0 Nop14-like family VHS PF00790.14 OAJ06255.1 - 4.2e-20 71.8 0.2 6.4e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 VHS domain PepSY_2 PF13670.1 OAJ06256.1 - 0.26 11.2 2.0 0.72 9.7 0.0 2.5 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain UCH PF00443.24 OAJ06257.1 - 1.1e-47 162.4 0.0 1.3e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ06257.1 - 4.7e-20 72.2 0.0 1.2e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 OAJ06257.1 - 1.8e-08 33.6 0.0 3.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 OAJ06257.1 - 0.0056 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Adaptin_N PF01602.15 OAJ06258.1 - 3.2e-146 487.7 7.4 4.1e-146 487.3 5.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 OAJ06258.1 - 2e-28 99.4 2.1 1.4e-24 86.9 0.1 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 OAJ06258.1 - 1.2e-18 67.1 4.5 1.3e-09 38.1 0.0 5.8 1 1 6 7 7 7 6 HEAT repeats HEAT PF02985.17 OAJ06258.1 - 9.3e-12 43.9 4.1 0.00075 19.3 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 OAJ06258.1 - 4.5e-08 33.3 4.7 0.00091 19.6 0.0 6.9 6 3 3 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 OAJ06258.1 - 0.00026 20.4 0.4 0.98 8.7 0.0 4.0 2 2 2 4 4 4 2 CLASP N terminal Cnd3 PF12719.2 OAJ06258.1 - 0.0061 15.5 0.1 0.068 12.1 0.0 2.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain Aminoglyc_resit PF10706.4 OAJ06258.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Phage_integrase PF00589.17 OAJ06259.1 - 6.4e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ06259.1 - 0.023 14.8 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 OAJ06259.1 - 0.18 12.1 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Ras PF00071.17 OAJ06260.1 - 6.8e-50 168.6 0.0 1.5e-49 167.5 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 OAJ06260.1 - 1.5e-18 67.4 0.0 2.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ06260.1 - 1.7e-05 24.1 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 OAJ06260.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit APG5 PF04106.7 OAJ06261.1 - 2.5e-45 154.4 0.0 5.9e-29 100.9 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg5 CTP_transf_2 PF01467.21 OAJ06262.1 - 5.1e-15 55.8 0.1 1.7e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase DUF2146 PF10220.4 OAJ06262.1 - 1.2 7.0 10.7 2.1 6.2 7.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Nop14 PF04147.7 OAJ06262.1 - 1.5 6.6 18.8 2.3 6.0 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 OAJ06262.1 - 7.5 6.0 13.7 20 4.6 9.5 1.7 1 0 0 1 1 1 0 Nucleoplasmin Noc2 PF03715.8 OAJ06263.1 - 9e-100 333.3 0.4 1.6e-99 332.5 0.1 1.5 2 0 0 2 2 2 1 Noc2p family WD40 PF00400.27 OAJ06263.1 - 9.7e-12 44.2 6.2 0.002 17.9 0.1 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box-like PF12937.2 OAJ06263.1 - 6.8e-11 41.7 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ06263.1 - 7.9e-05 22.1 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 OAJ06263.1 - 0.00087 18.6 12.9 0.0054 16.2 2.1 4.2 3 0 0 3 3 3 2 Ubiquitin interaction motif RrnaAD PF00398.15 OAJ06264.1 - 1.1e-55 188.4 0.0 1.5e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 OAJ06264.1 - 3.7e-10 39.8 0.0 6.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ06264.1 - 2.2e-05 23.8 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 OAJ06264.1 - 2.8e-05 23.3 0.0 4.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 OAJ06264.1 - 2.8e-05 24.6 0.0 6.1e-05 23.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 OAJ06264.1 - 6e-05 22.6 0.0 9.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 OAJ06264.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 OAJ06264.1 - 0.00027 20.5 0.0 0.00065 19.3 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 NodS PF05401.6 OAJ06264.1 - 0.002 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.7 OAJ06264.1 - 0.0025 18.2 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ06264.1 - 0.0045 16.7 0.0 0.0082 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ06264.1 - 0.041 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 OAJ06264.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 OAJ06264.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 OAJ06264.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF676 PF05057.9 OAJ06265.1 - 0.0065 15.7 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) adh_short PF00106.20 OAJ06267.1 - 3.4e-21 75.8 0.2 4.4e-21 75.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ06267.1 - 2.1e-09 37.5 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ06267.1 - 8.5e-08 32.0 0.2 1.4e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 OAJ06267.1 - 8.1e-05 22.3 0.2 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.9 OAJ06267.1 - 0.02 14.2 0.1 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Epimerase PF01370.16 OAJ06267.1 - 0.036 13.5 0.1 0.11 11.8 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 OAJ06267.1 - 0.058 13.4 0.2 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.19 OAJ06267.1 - 0.071 11.9 2.2 0.68 8.7 0.0 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase Ribosomal_S4 PF00163.14 OAJ06269.1 - 2.4e-27 95.1 0.9 5.1e-27 94.1 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 OAJ06269.1 - 4.5e-12 45.2 1.5 4.5e-12 45.2 1.0 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 OAJ06270.1 - 3.3e-37 126.2 1.8 3.3e-37 126.2 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Rootletin PF15035.1 OAJ06271.1 - 0.068 13.1 22.6 0.19 11.6 6.1 2.9 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion AAA_13 PF13166.1 OAJ06271.1 - 0.082 11.3 0.7 0.16 10.4 0.5 1.4 1 0 0 1 1 1 0 AAA domain RasGEF PF00617.14 OAJ06272.1 - 2.1e-43 148.2 0.0 4.1e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 OAJ06272.1 - 2.3e-10 40.5 0.3 4.5e-10 39.5 0.2 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif RINGv PF12906.2 OAJ06273.1 - 1.8e-06 27.8 7.9 6.5e-06 26.0 1.9 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 OAJ06273.1 - 0.012 15.4 4.2 0.012 15.4 2.9 2.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.1 OAJ06273.1 - 0.072 12.6 2.1 0.15 11.6 1.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 OAJ06273.1 - 0.17 11.8 1.5 0.4 10.6 1.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-rbx1 PF12678.2 OAJ06273.1 - 4.7 7.3 8.6 13 5.9 6.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger OTU PF02338.14 OAJ06274.1 - 3.7e-15 56.5 0.0 6.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 OAJ06274.1 - 0.0082 15.5 0.0 0.83 8.9 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain Gp_dh_C PF02800.15 OAJ06275.1 - 9.2e-73 242.8 0.0 1.3e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 OAJ06275.1 - 5.6e-59 198.4 0.1 9e-59 197.7 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain LEAP-2 PF07359.6 OAJ06276.1 - 0.016 14.8 0.1 0.016 14.8 0.1 8.4 8 3 2 10 10 10 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Dimer_Tnp_hAT PF05699.9 OAJ06281.1 - 1.8e-18 65.9 0.0 4e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 OAJ06282.1 - 8.4e-47 159.4 0.0 1.2e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06282.1 - 2.9e-24 85.5 0.0 1.2e-23 83.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06282.1 - 4e-06 26.0 0.0 2.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PBP1_TM PF14812.1 OAJ06282.1 - 0.3 11.4 7.8 0.6 10.4 5.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal p450 PF00067.17 OAJ06283.1 - 7.3e-58 196.1 0.0 1.7e-57 194.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ06284.1 - 1.2e-66 225.2 0.0 1.8e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2680 PF10925.3 OAJ06284.1 - 0.14 12.0 0.1 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) WD40 PF00400.27 OAJ06286.1 - 2e-15 56.0 0.3 2.1e-05 24.2 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HSP70 PF00012.15 OAJ06287.1 - 4.1e-49 167.0 9.9 2.1e-44 151.4 0.0 4.1 2 2 1 3 3 3 2 Hsp70 protein DDR PF08841.5 OAJ06287.1 - 0.014 14.2 0.3 0.16 10.7 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Prefoldin PF02996.12 OAJ06287.1 - 0.29 10.7 3.1 0.68 9.5 0.0 2.9 3 1 1 4 4 4 0 Prefoldin subunit GMC_oxred_N PF00732.14 OAJ06288.1 - 4.4e-59 200.0 0.0 6.1e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ06288.1 - 1.1e-30 106.8 0.0 2.3e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 OAJ06288.1 - 7.8e-07 28.3 0.0 2e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAJ06288.1 - 0.00016 21.8 0.0 0.089 12.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ06288.1 - 0.0002 21.2 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ06288.1 - 0.00084 18.2 1.5 0.0015 17.4 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 OAJ06288.1 - 0.0043 16.0 0.4 0.0064 15.4 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 OAJ06288.1 - 0.01 14.3 0.3 0.018 13.5 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 OAJ06288.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ06288.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.19 OAJ06293.1 - 1.2e-35 123.0 17.0 2.2e-35 122.0 11.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ06293.1 - 3.1e-28 98.5 34.7 5.1e-28 97.7 24.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 OAJ06293.1 - 0.0087 15.8 0.7 2.9 7.7 0.1 2.5 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.8 OAJ06293.1 - 0.12 10.5 8.0 0.077 11.1 1.1 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Tim17 PF02466.14 OAJ06294.1 - 2.1e-26 92.4 7.5 2.6e-26 92.1 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3684 PF12449.3 OAJ06295.1 - 4.5e-284 945.1 0.1 2.5e-265 883.0 0.0 5.0 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) Sugar_tr PF00083.19 OAJ06296.1 - 4.3e-32 111.2 25.6 1.4e-31 109.6 17.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ06296.1 - 4.9e-29 101.1 41.3 1e-28 100.1 27.4 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Polysacc_lyase PF14099.1 OAJ06297.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase Redoxin PF08534.5 OAJ06298.1 - 8.5e-28 96.7 0.0 9.7e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ06298.1 - 9.7e-10 38.1 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Dsl1_C PF11989.3 OAJ06299.1 - 0.068 12.3 0.0 0.087 11.9 0.0 1.1 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal GCR1_C PF12550.3 OAJ06300.1 - 9.3e-15 54.2 0.0 1.9e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sporozoite_P67 PF05642.6 OAJ06300.1 - 0.096 10.5 2.8 0.16 9.8 1.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF106 PF01956.11 OAJ06301.1 - 1.4e-57 193.8 0.6 1.7e-57 193.6 0.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 Cwf_Cwc_15 PF04889.7 OAJ06302.1 - 2.3e-67 227.2 17.1 2.7e-67 227.0 11.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.6 OAJ06302.1 - 1.8 6.8 19.0 2.2 6.5 13.2 1.1 1 0 0 1 1 1 0 SGT1 protein CENP-T PF15511.1 OAJ06302.1 - 2.2 7.4 27.2 3.7 6.6 18.9 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PX PF00787.19 OAJ06303.1 - 5.4e-17 61.6 0.0 1.1e-15 57.3 0.0 2.4 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 OAJ06303.1 - 9.3e-07 28.3 0.2 1.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF1408 PF07193.6 OAJ06303.1 - 0.26 10.8 0.1 0.48 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) p450 PF00067.17 OAJ06304.1 - 1.2e-62 211.9 0.0 2.7e-62 210.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ06305.1 - 1.5e-81 274.2 0.0 8.5e-62 209.1 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Cortexin PF11057.3 OAJ06305.1 - 0.028 14.0 0.2 9.3 5.9 0.1 2.6 2 0 0 2 2 2 0 Cortexin of kidney Zn_clus PF00172.13 OAJ06306.1 - 2.4e-07 30.5 10.7 3.8e-07 29.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.4 OAJ06307.1 - 1.2e-74 251.1 0.0 2.3e-74 250.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ06307.1 - 0.0061 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 OAJ06307.1 - 0.039 13.6 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal An_peroxidase PF03098.10 OAJ06308.1 - 6.1e-77 259.1 0.0 1.7e-74 251.1 0.0 2.4 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 OAJ06308.1 - 6.9e-12 44.6 0.0 1.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Lyase_1 PF00206.15 OAJ06309.1 - 5.7e-22 78.3 0.0 8.6e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 OAJ06309.1 - 4.6e-17 61.7 0.0 9.6e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus G-patch_2 PF12656.2 OAJ06310.1 - 3.7e-23 81.1 0.4 3.7e-23 81.1 0.3 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 OAJ06310.1 - 2.7e-06 27.0 3.2 4.9e-06 26.2 2.2 1.5 1 0 0 1 1 1 1 G-patch domain Raftlin PF15250.1 OAJ06310.1 - 0.2 10.1 2.1 0.26 9.7 1.4 1.2 1 0 0 1 1 1 0 Raftlin Med13_C PF06333.7 OAJ06311.1 - 2e-06 26.6 2.0 2.2e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal zf-C3HC4_2 PF13923.1 OAJ06312.1 - 1.4e-08 34.6 1.5 1.4e-08 34.6 1.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ06312.1 - 2.8e-08 33.4 4.1 9.5e-08 31.7 0.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ06312.1 - 1.5e-07 30.9 3.0 2.2e-06 27.2 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ06312.1 - 2.8e-07 30.0 1.3 2.8e-07 30.0 0.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ06312.1 - 4.7e-05 23.0 1.5 4.7e-05 23.0 1.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 OAJ06312.1 - 6.9e-05 22.6 2.2 6.9e-05 22.6 1.5 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 OAJ06312.1 - 7.3e-05 22.4 0.9 0.00019 21.0 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DUF1644 PF07800.7 OAJ06312.1 - 0.0011 18.8 0.5 0.71 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1644) FKBP_C PF00254.23 OAJ06314.1 - 9.6e-28 96.0 0.0 2.2e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PBP1_TM PF14812.1 OAJ06314.1 - 0.0056 16.9 5.2 0.0056 16.9 3.6 4.1 3 1 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Macoilin PF09726.4 OAJ06314.1 - 0.27 9.4 14.7 0.39 8.9 10.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 OAJ06314.1 - 1.5 7.1 39.4 1.1 7.6 4.5 2.0 2 0 0 2 2 2 0 Daxx Family Borrelia_P83 PF05262.6 OAJ06314.1 - 4.1 5.5 22.1 5.7 5.1 15.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.1 OAJ06314.1 - 6 7.1 7.5 8.8 6.6 5.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PBP1_TM PF14812.1 OAJ06315.1 - 2.4 8.5 5.2 1 9.7 1.8 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MULE PF10551.4 OAJ06316.1 - 2.1e-12 46.9 0.6 1.2e-10 41.4 0.4 2.6 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 OAJ06316.1 - 0.018 14.5 0.3 0.043 13.2 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger MFS_1 PF07690.11 OAJ06317.1 - 1.2e-38 132.7 48.8 1.6e-33 115.9 32.4 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 OAJ06318.1 - 2.1e-51 174.6 0.0 3e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06318.1 - 0.02 15.8 0.1 0.042 14.7 0.1 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain KH_1 PF00013.24 OAJ06319.1 - 2.9e-81 267.0 37.0 1.6e-12 46.8 0.0 14.1 14 1 0 14 14 14 10 KH domain KH_3 PF13014.1 OAJ06319.1 - 2.2e-62 205.8 22.3 1.8e-08 33.8 0.0 11.5 12 0 0 12 12 12 9 KH domain KH_2 PF07650.12 OAJ06319.1 - 1.7e-12 46.7 24.6 0.058 12.9 0.1 9.0 8 1 1 9 9 9 6 KH domain KH_4 PF13083.1 OAJ06319.1 - 4.5e-06 26.2 17.5 1.1 8.8 0.0 8.6 6 1 2 8 8 8 3 KH domain Lipoprotein_17 PF04200.7 OAJ06319.1 - 0.096 12.8 0.4 0.36 10.9 0.3 2.0 1 0 0 1 1 1 0 Lipoprotein associated domain Acylphosphatase PF00708.13 OAJ06319.1 - 0.52 10.4 7.8 20 5.3 0.0 5.6 6 0 0 6 6 6 0 Acylphosphatase DPBB_1 PF03330.13 OAJ06320.1 - 2.5e-09 37.0 0.2 6.7e-09 35.6 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ06320.1 - 0.015 14.9 0.2 0.026 14.1 0.1 1.4 1 1 0 1 1 1 0 Barwin family TAP35_44 PF07265.6 OAJ06320.1 - 0.079 12.7 0.5 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 DUF3357 PF11837.3 OAJ06320.1 - 0.11 12.3 0.3 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Misat_Tub_SegII PF10644.4 OAJ06321.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DUF3414 PF11894.3 OAJ06324.1 - 2e-239 797.5 5.4 2.6e-239 797.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) DUF1162 PF06650.7 OAJ06325.1 - 1.2e-73 247.7 0.0 1.8e-72 243.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 OAJ06325.1 - 1.1e-08 35.1 0.0 7.1e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 ATG C terminal domain DUF3038 PF11237.3 OAJ06329.1 - 0.058 13.1 0.7 0.089 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Hydantoinase_A PF01968.13 OAJ06329.1 - 0.083 11.9 0.2 0.097 11.7 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase NDUF_C2 PF06374.6 OAJ06329.1 - 0.11 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Nop25 PF09805.4 OAJ06329.1 - 0.32 11.0 6.0 0.46 10.5 4.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Lipase_3 PF01764.20 OAJ06336.1 - 1.1e-06 28.3 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 OAJ06336.1 - 0.036 13.8 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lyase_1 PF00206.15 OAJ06337.1 - 1.9e-116 388.6 0.0 2.9e-116 388.0 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 OAJ06337.1 - 9.7e-20 70.3 0.0 3e-19 68.8 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 OAJ06337.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain CPSF100_C PF13299.1 OAJ06338.1 - 1.9e-26 93.1 0.0 6.9e-26 91.3 0.0 2.0 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 OAJ06338.1 - 5.7e-16 58.6 0.0 1.3e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Acyltransferase PF01553.16 OAJ06339.1 - 4.1e-35 120.1 0.0 6.2e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase LNP1 PF15419.1 OAJ06343.1 - 0.34 10.9 2.4 0.26 11.3 0.4 1.6 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 GPI-anchored PF10342.4 OAJ06344.1 - 2.1e-10 40.9 2.0 2.1e-10 40.9 1.4 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SOG2 PF10428.4 OAJ06344.1 - 0.097 11.3 6.7 0.098 11.2 4.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SSP160 PF06933.6 OAJ06344.1 - 0.5 8.2 22.8 0.85 7.5 15.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PAP1 PF08601.5 OAJ06344.1 - 4.8 6.7 11.5 6.6 6.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Sporozoite_P67 PF05642.6 OAJ06344.1 - 4.8 4.9 15.2 5.6 4.6 10.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PEX11 PF05648.9 OAJ06345.1 - 4.2e-62 209.3 2.2 4.7e-62 209.1 1.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DNApol3-delta_C PF09115.5 OAJ06345.1 - 0.033 14.2 0.1 0.067 13.2 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal FTCD_C PF04961.7 OAJ06345.1 - 0.043 13.2 1.4 0.12 11.7 0.5 1.9 1 1 1 2 2 2 0 Formiminotransferase-cyclodeaminase DUF155 PF02582.9 OAJ06346.1 - 4.7e-52 176.4 0.0 8.5e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 CDC45 PF02724.9 OAJ06346.1 - 0.49 8.3 7.3 0.89 7.5 5.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.8 OAJ06347.1 - 2.8 5.9 4.2 4 5.4 2.9 1.1 1 0 0 1 1 1 0 Menin DUF912 PF06024.7 OAJ06348.1 - 0.17 11.9 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF588 PF04535.7 OAJ06348.1 - 2.2 7.8 5.4 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF588) MFS_1 PF07690.11 OAJ06349.1 - 4.8e-40 137.3 34.6 4e-39 134.3 23.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06349.1 - 2.3e-11 42.9 11.4 2.3e-11 42.9 7.9 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2014 PF09427.5 OAJ06349.1 - 0.063 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Exo_endo_phos PF03372.18 OAJ06350.1 - 6e-15 55.8 0.1 8.7e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AMP-binding PF00501.23 OAJ06351.1 - 7.7e-49 166.1 0.0 1.4e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 OAJ06351.1 - 4.3e-11 42.9 1.2 8.1e-11 42.0 0.4 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Hexapep PF00132.19 OAJ06351.1 - 1.1e-10 40.4 0.2 0.00048 19.4 0.0 6.2 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.1 OAJ06351.1 - 1e-08 35.9 2.9 7.3e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.1 OAJ06351.1 - 0.14 11.7 4.6 17 5.0 0.1 4.6 5 1 1 6 6 6 0 Hexapeptide repeat of succinyl-transferase GH3 PF03321.8 OAJ06351.1 - 0.46 8.9 0.1 14 4.0 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DnaJ PF00226.26 OAJ06353.1 - 2.9e-24 84.5 0.5 4.9e-24 83.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 OAJ06353.1 - 1.8e-15 57.1 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Ashwin PF15323.1 OAJ06353.1 - 0.081 12.9 4.5 0.12 12.3 3.2 1.2 1 0 0 1 1 1 0 Developmental protein SR-25 PF10500.4 OAJ06353.1 - 0.15 11.4 9.8 0.26 10.7 6.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cpn60_TCP1 PF00118.19 OAJ06354.1 - 1.7e-148 495.2 0.4 2e-148 495.0 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.17 OAJ06356.1 - 2.7e-17 62.1 0.0 6.7e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06356.1 - 6.3e-13 48.3 0.0 9.8e-07 28.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06356.1 - 1.7e-12 47.1 0.0 9.7e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IATP PF04568.7 OAJ06356.1 - 1.8 8.6 7.9 22 5.1 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Sas10_Utp3 PF04000.10 OAJ06358.1 - 2.4e-07 30.8 0.1 4.4e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Metallophos PF00149.23 OAJ06360.1 - 0.00021 20.7 2.1 0.0003 20.2 0.7 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase CBF PF03914.12 OAJ06361.1 - 1.5e-34 118.8 0.1 1.1e-33 116.0 0.1 2.3 2 0 0 2 2 2 1 CBF/Mak21 family adh_short PF00106.20 OAJ06362.1 - 2.3e-11 43.8 0.5 1.2e-09 38.3 0.3 2.4 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 OAJ06362.1 - 9.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ06362.1 - 1.8e-06 28.0 0.0 9.6e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 OAJ06362.1 - 2.7e-05 24.0 0.0 4.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAJ06362.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.5 OAJ06362.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.7 1 1 1 2 2 2 0 KR domain PseudoU_synth_1 PF01416.15 OAJ06363.1 - 1.8e-22 79.7 0.0 2e-12 47.4 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase NAD_binding_10 PF13460.1 OAJ06364.1 - 1.6e-10 41.2 0.0 2.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 OAJ06364.1 - 2e-10 40.8 3.4 5.2e-08 32.9 2.4 3.1 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 OAJ06364.1 - 5.2e-08 32.6 0.0 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAJ06364.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 OAJ06365.1 - 1.8e-11 44.2 1.4 1.2e-09 38.3 0.2 3.2 2 2 1 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ06365.1 - 1.2e-08 35.1 0.0 1.6e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ06365.1 - 5.2e-08 32.6 0.0 1.7e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 OAJ06365.1 - 2.1e-06 27.7 0.0 3.7e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ06365.1 - 0.0001 22.0 0.0 0.21 11.2 0.0 3.0 2 1 1 3 3 3 2 KR domain Eno-Rase_NADH_b PF12242.3 OAJ06365.1 - 0.0042 16.8 0.3 0.032 14.0 0.0 2.4 2 1 1 3 3 3 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 OAJ06365.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DEDD_Tnp_IS110 PF01548.12 OAJ06365.1 - 0.11 12.2 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Transposase Tmemb_14 PF03647.8 OAJ06366.1 - 7e-19 68.0 8.9 8.6e-19 67.7 6.2 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C VHS PF00790.14 OAJ06367.1 - 8e-38 129.2 0.9 1.5e-37 128.3 0.0 1.8 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 OAJ06367.1 - 2.4e-16 59.3 8.9 4.5e-16 58.5 6.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 OAJ06367.1 - 5e-05 22.5 7.5 0.0051 16.2 0.6 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 OAJ06367.1 - 0.00014 21.7 2.6 0.00024 20.9 1.8 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger DUF3602 PF12223.3 OAJ06367.1 - 0.0096 16.2 1.3 0.0096 16.2 0.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) Nucleo_P87 PF07267.6 OAJ06367.1 - 0.21 10.2 0.7 0.3 9.7 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-RING_5 PF14634.1 OAJ06367.1 - 0.8 9.4 10.8 1.3 8.7 7.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 OAJ06368.1 - 6.9e-56 189.2 0.0 3.6e-55 186.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06368.1 - 3e-25 88.7 0.0 5.9e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PY_rept_46 PF09689.5 OAJ06368.1 - 0.0013 19.0 1.8 0.0055 17.0 1.2 2.1 1 0 0 1 1 1 1 Plasmodium yoelii repeat (PY_rept_46) Kinase-like PF14531.1 OAJ06368.1 - 0.006 15.5 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ06368.1 - 0.009 15.7 0.1 0.044 13.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Tautomerase_3 PF14832.1 OAJ06370.1 - 3.5e-40 137.1 0.0 4.1e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Ribosomal_L12 PF00542.14 OAJ06373.1 - 1.9e-19 69.4 10.9 3.2e-19 68.6 4.6 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Med3 PF11593.3 OAJ06373.1 - 4.3 6.4 15.6 5.6 6.0 10.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S14 PF00253.16 OAJ06374.1 - 6.9e-19 66.9 0.1 1.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RNA_pol_Rpb6 PF01192.17 OAJ06375.1 - 4.8e-21 74.2 0.4 6.9e-21 73.7 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 adh_short PF00106.20 OAJ06377.1 - 5.8e-11 42.5 1.1 4.8e-09 36.3 0.4 2.8 2 1 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 OAJ06377.1 - 7e-09 35.4 0.0 8.7e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ06377.1 - 1.1e-07 32.0 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 OAJ06377.1 - 0.0003 20.6 0.1 0.00051 19.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAJ06377.1 - 0.029 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ish1 PF10281.4 OAJ06382.1 - 7.6e-47 156.9 24.9 1.2e-10 41.2 0.2 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.22 OAJ06382.1 - 0.0025 17.3 0.0 2.5 7.6 0.0 4.0 4 0 0 4 4 4 1 SAP domain Apolipoprotein PF01442.13 OAJ06382.1 - 0.0027 17.2 0.3 0.064 12.7 0.0 2.8 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1939 PF09154.5 OAJ06382.1 - 0.1 12.5 4.5 0.42 10.5 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) LEM PF03020.10 OAJ06382.1 - 0.12 11.8 0.0 11 5.5 0.0 3.4 5 0 0 5 5 5 0 LEM domain DUF1470 PF07336.6 OAJ06382.1 - 0.54 10.5 4.5 5.2 7.4 0.5 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1470) DUF2404 PF10296.4 OAJ06383.1 - 1.8e-28 98.4 0.0 3.5e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) NARP1 PF12569.3 OAJ06384.1 - 1.6e-165 551.8 8.9 1.6e-165 551.8 6.2 1.7 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 OAJ06384.1 - 1.8e-15 55.5 15.3 1.7e-05 24.3 0.0 9.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ06384.1 - 1.5e-11 43.3 3.3 3.5e-05 23.2 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ06384.1 - 2.4e-11 42.5 10.1 0.0055 16.4 0.0 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ06384.1 - 6.7e-09 35.9 41.0 0.00069 19.9 0.0 9.4 8 1 2 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ06384.1 - 4.1e-08 33.1 43.0 0.074 13.7 0.1 10.8 11 2 1 12 12 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ06384.1 - 4.2e-08 32.7 0.3 2.3e-05 23.9 0.1 7.2 6 1 2 8 8 7 2 TPR repeat TPR_17 PF13431.1 OAJ06384.1 - 1.8e-07 30.7 1.1 2.6 8.4 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ06384.1 - 2.3e-07 31.2 58.4 0.061 14.0 0.0 10.8 11 1 1 12 12 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ06384.1 - 3.8e-06 26.7 30.0 0.006 16.4 0.1 7.6 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ06384.1 - 0.00012 21.5 4.5 0.11 12.3 0.0 5.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ06384.1 - 0.0032 17.3 0.1 0.0032 17.3 0.1 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ06384.1 - 0.017 15.5 0.1 0.017 15.5 0.1 9.0 11 1 0 11 11 9 0 Tetratricopeptide repeat DUF816 PF05674.7 OAJ06384.1 - 0.1 12.3 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF816) Ins_allergen_rp PF06757.8 OAJ06384.1 - 0.29 10.5 3.0 0.34 10.3 0.0 2.6 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification Pkinase PF00069.20 OAJ06385.1 - 2.9e-39 134.7 0.0 3.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06385.1 - 5.3e-16 58.4 0.0 7.7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ06385.1 - 4.4e-06 26.6 0.3 0.0029 17.3 0.0 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 OAJ06385.1 - 0.021 13.6 0.1 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Methyltransf_28 PF02636.12 OAJ06386.1 - 1.1e-32 113.4 0.0 2.1e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.5 OAJ06386.1 - 3e-28 98.6 8.9 9.5e-10 37.9 0.0 6.1 5 1 0 5 5 5 3 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.15 OAJ06386.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 OAJ06386.1 - 0.018 15.5 0.0 0.087 13.3 0.0 2.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ06386.1 - 0.065 13.2 1.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain MOFRL PF05161.8 OAJ06387.1 - 0.097 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 MOFRL family CP2 PF04516.10 OAJ06387.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 CP2 transcription factor Ferritin_2 PF13668.1 OAJ06388.1 - 4.5e-47 159.4 3.1 7.1e-47 158.7 2.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF3635 PF12330.3 OAJ06389.1 - 7.8e-14 51.5 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Nucleoplasmin PF03066.10 OAJ06389.1 - 0.045 13.2 4.4 0.13 11.8 3.0 1.7 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 OAJ06389.1 - 3.5 7.4 18.6 0.55 10.0 9.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 OAJ06389.1 - 5.3 7.3 13.5 0.3 11.3 5.0 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_L1 PF00687.16 OAJ06390.1 - 3e-23 82.3 0.0 1.1e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family TP_methylase PF00590.15 OAJ06390.1 - 0.001 18.8 1.4 0.0047 16.6 0.1 2.2 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Chlorosome_CsmC PF11098.3 OAJ06390.1 - 0.034 13.8 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C CWC25 PF12542.3 OAJ06391.1 - 3.4e-25 88.3 1.0 3.4e-25 88.3 0.7 3.5 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 OAJ06391.1 - 1.2e-13 50.7 12.2 1.2e-13 50.7 8.5 3.7 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR RNA_pol_Rpb2_6 PF00562.23 OAJ06392.1 - 3.5e-123 411.1 0.1 6.1e-118 393.9 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 OAJ06392.1 - 2.1e-64 216.2 0.0 3.3e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 OAJ06392.1 - 1e-46 158.7 0.0 1.9e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 OAJ06392.1 - 2.1e-28 98.4 0.1 6.4e-28 96.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 OAJ06392.1 - 9.8e-25 86.1 0.1 2.2e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 OAJ06392.1 - 8e-24 83.1 0.1 1.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 OAJ06392.1 - 5.9e-19 67.7 0.1 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 AMP-binding PF00501.23 OAJ06393.1 - 1.8e-94 316.4 0.0 2.3e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06393.1 - 1.3e-07 32.4 0.3 3.8e-07 30.9 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF663 PF04950.7 OAJ06394.1 - 2.1e-80 269.8 0.0 1.5e-79 267.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 OAJ06394.1 - 4.7e-21 74.1 0.0 9.5e-21 73.1 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Nop14 PF04147.7 OAJ06394.1 - 2.6 5.8 16.4 4.4 5.1 11.4 1.3 1 0 0 1 1 1 0 Nop14-like family Rogdi_lz PF10259.4 OAJ06395.1 - 0.012 14.7 1.9 0.016 14.3 1.3 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RabGAP-TBC PF00566.13 OAJ06396.1 - 4.2e-21 75.4 3.2 1.2e-17 64.1 0.9 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Hydrophob_seed PF14547.1 OAJ06396.1 - 0.023 14.5 0.2 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Hydrophobic seed protein HA2 PF04408.18 OAJ06397.1 - 7.6e-19 67.6 0.1 3e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ06397.1 - 4.6e-13 48.8 0.1 1.3e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 OAJ06397.1 - 6.4e-10 38.8 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 OAJ06397.1 - 4.9e-09 35.8 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ06397.1 - 1.5e-06 28.3 0.1 1.2e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 OAJ06397.1 - 0.0052 16.5 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 OAJ06397.1 - 0.037 13.5 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 OAJ06397.1 - 0.063 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 OAJ06397.1 - 0.071 12.8 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 OAJ06397.1 - 0.087 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 KaiC LTV PF04180.9 OAJ06398.1 - 3.3e-48 165.2 26.7 1.2e-47 163.4 9.4 3.2 2 1 0 2 2 2 2 Low temperature viability protein CENP-B_dimeris PF09026.5 OAJ06398.1 - 1.2 9.4 22.2 0.44 10.8 5.9 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain adh_short_C2 PF13561.1 OAJ06399.1 - 3.8e-29 102.1 0.1 4.5e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 OAJ06399.1 - 6.9e-28 97.6 1.0 9.1e-28 97.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ06399.1 - 3.7e-12 46.2 0.2 5.8e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 OAJ06399.1 - 0.025 13.7 0.3 0.056 12.5 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIM-br_sig_trns PF09370.5 OAJ06399.1 - 0.035 13.1 0.5 0.16 11.0 0.2 1.9 2 0 0 2 2 2 0 TIM-barrel signal transduction protein F420_oxidored PF03807.12 OAJ06399.1 - 0.036 14.4 0.3 0.076 13.4 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 OAJ06399.1 - 0.039 13.3 0.3 0.076 12.4 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 OAJ06399.1 - 0.068 12.8 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Med7 PF05983.6 OAJ06400.1 - 8.7e-32 110.1 5.9 3.3e-16 59.5 0.1 2.0 2 0 0 2 2 2 2 MED7 protein DUF607 PF04678.8 OAJ06400.1 - 0.021 14.7 0.2 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF342 PF03961.8 OAJ06400.1 - 0.031 12.7 0.1 0.041 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4131 PF13567.1 OAJ06406.1 - 6.9 6.0 10.3 1.8 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 OAJ06407.1 - 5.1e-57 192.9 0.0 7.4e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06407.1 - 2.5e-19 69.3 0.0 4.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ06407.1 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 OAJ06407.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 OAJ06407.1 - 0.12 11.8 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 OAJ06407.1 - 0.85 7.4 26.9 0.035 12.0 3.7 2.2 2 0 0 2 2 2 0 Nop14-like family Tetraspannin PF00335.15 OAJ06409.1 - 0.00053 19.3 3.3 0.00053 19.3 2.3 2.0 1 1 0 2 2 2 1 Tetraspanin family Shisa PF13908.1 OAJ06409.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PalH PF08733.5 OAJ06409.1 - 0.1 11.4 1.4 0.088 11.6 0.2 1.4 2 0 0 2 2 2 0 PalH/RIM21 EVI2A PF05399.6 OAJ06409.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF3328 PF11807.3 OAJ06409.1 - 0.17 11.5 0.4 27 4.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) YtpI PF14007.1 OAJ06409.1 - 0.25 11.2 0.1 0.25 11.2 0.0 2.4 2 1 0 2 2 2 0 YtpI-like protein Tic20 PF09685.5 OAJ06409.1 - 0.61 10.0 5.6 1.7 8.6 0.3 2.8 3 0 0 3 3 3 0 Tic20-like protein DoxX_2 PF13564.1 OAJ06409.1 - 6.5 6.7 11.7 7.3 6.6 5.9 2.4 2 1 0 2 2 2 0 DoxX-like family Kri1_C PF12936.2 OAJ06410.1 - 7.6e-24 83.4 0.1 7.6e-24 83.4 0.1 5.6 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 OAJ06410.1 - 4.1e-20 71.9 12.8 4.1e-20 71.9 8.9 7.5 7 1 1 8 8 8 1 KRI1-like family DUF2235 PF09994.4 OAJ06412.1 - 2e-62 211.0 0.0 2.9e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 OAJ06412.1 - 0.044 13.5 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-CCCH PF00642.19 OAJ06413.1 - 0.19 11.4 10.3 1.6 8.5 2.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MFS_1 PF07690.11 OAJ06414.1 - 2.6e-36 125.0 73.7 4.6e-32 111.1 29.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 OAJ06415.1 - 0.32 10.2 5.4 1.5 8.0 1.0 2.2 1 1 1 2 2 2 0 Tetraspanin family Pkinase PF00069.20 OAJ06416.1 - 2e-55 187.7 0.0 2.9e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06416.1 - 1.5e-18 66.8 0.0 3.1e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TIP49 PF06068.8 OAJ06417.1 - 1.2e-172 574.1 0.2 1.4e-172 573.8 0.2 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 OAJ06417.1 - 5.1e-12 46.1 0.7 3e-09 37.1 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ06417.1 - 1.2e-11 44.0 0.6 1.7e-08 33.7 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 OAJ06417.1 - 3.6e-08 33.6 0.0 1.6e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ06417.1 - 2.4e-07 30.9 0.1 0.0065 16.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain DnaB_C PF03796.10 OAJ06417.1 - 6.2e-06 25.2 0.1 1.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 OAJ06417.1 - 9.2e-06 25.4 0.2 0.0036 17.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 OAJ06417.1 - 1.9e-05 23.9 0.6 0.00072 18.7 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 OAJ06417.1 - 7.1e-05 22.3 0.0 0.083 12.3 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 OAJ06417.1 - 8e-05 22.3 0.0 0.00034 20.3 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 OAJ06417.1 - 0.00016 21.1 0.2 0.00045 19.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ06417.1 - 0.00018 22.3 0.1 0.001 19.8 0.0 2.2 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 OAJ06417.1 - 0.0004 19.8 0.0 0.0009 18.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 OAJ06417.1 - 0.00046 20.0 0.0 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 OAJ06417.1 - 0.00096 18.0 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 OAJ06417.1 - 0.001 18.2 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 OAJ06417.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 OAJ06417.1 - 0.0024 18.1 0.3 0.0099 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ06417.1 - 0.0083 16.0 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 OAJ06417.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 OAJ06417.1 - 0.011 14.7 0.1 0.03 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 OAJ06417.1 - 0.016 14.4 0.1 0.039 13.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 OAJ06417.1 - 0.016 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 OAJ06417.1 - 0.019 15.2 0.1 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 OAJ06417.1 - 0.022 13.4 0.9 0.032 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 OAJ06417.1 - 0.03 14.3 0.5 0.059 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 OAJ06417.1 - 0.03 14.1 0.2 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 OAJ06417.1 - 0.032 13.1 0.4 1.3 7.8 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_2 PF07724.9 OAJ06417.1 - 0.036 13.9 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_29 PF13555.1 OAJ06417.1 - 0.047 13.2 0.2 1.2 8.7 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 OAJ06417.1 - 0.048 13.7 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 OAJ06417.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 OAJ06417.1 - 0.085 12.5 0.2 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase NTPase_1 PF03266.10 OAJ06417.1 - 0.13 11.9 1.9 0.42 10.3 0.3 2.5 2 1 0 2 2 2 0 NTPase Sipho_tail PF05709.6 OAJ06417.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein CDP-OH_P_transf PF01066.16 OAJ06418.1 - 2e-11 44.0 1.4 4.2e-11 43.0 1.0 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CM_2 PF01817.16 OAJ06419.1 - 0.00039 20.4 0.0 0.97 9.5 0.0 2.3 2 0 0 2 2 2 2 Chorismate mutase type II Ribosomal_L31e PF01198.14 OAJ06420.1 - 8.5e-34 115.0 2.8 1.2e-33 114.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e RNA_POL_M_15KD PF02150.11 OAJ06421.1 - 3.2e-13 49.1 3.7 3.2e-13 49.1 2.6 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 OAJ06421.1 - 3.5e-11 42.5 13.8 8.6e-11 41.2 2.8 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) GFA PF04828.9 OAJ06421.1 - 0.00079 19.3 6.0 0.0045 16.8 0.1 2.5 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 OAJ06421.1 - 0.00086 19.5 5.2 0.047 13.9 0.9 2.2 2 0 0 2 2 2 2 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 OAJ06421.1 - 0.05 13.5 10.8 2.3 8.2 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Elf1 PF05129.8 OAJ06421.1 - 0.063 12.9 4.6 2.1 8.0 0.3 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ribbon_3 PF13248.1 OAJ06421.1 - 0.14 11.4 0.1 0.14 11.4 0.1 3.4 4 0 0 4 4 3 0 zinc-ribbon domain DZR PF12773.2 OAJ06421.1 - 0.17 11.7 11.7 0.27 11.1 0.3 2.8 2 1 1 3 3 3 0 Double zinc ribbon zf-ISL3 PF14690.1 OAJ06421.1 - 0.23 11.5 2.4 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HNH_5 PF14279.1 OAJ06421.1 - 1.2 9.2 10.6 5.1 7.1 0.1 3.2 2 2 1 3 3 3 0 HNH endonuclease Rubredoxin PF00301.15 OAJ06421.1 - 1.2 9.0 8.3 6.7 6.6 0.0 3.7 4 0 0 4 4 4 0 Rubredoxin Zn_Tnp_IS1595 PF12760.2 OAJ06421.1 - 1.6 8.6 12.2 8 6.3 3.1 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_4 PF13894.1 OAJ06421.1 - 2.2 8.8 10.7 2.8 8.4 0.4 3.5 4 0 0 4 4 3 0 C2H2-type zinc finger TF_Zn_Ribbon PF08271.7 OAJ06421.1 - 2.3 7.6 13.2 0.084 12.2 2.0 3.1 3 1 1 4 4 4 0 TFIIB zinc-binding DUF3268 PF11672.3 OAJ06421.1 - 2.3 8.3 6.8 8.3 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) C1_4 PF07975.7 OAJ06421.1 - 2.3 8.2 15.7 0.46 10.5 1.1 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain OrfB_Zn_ribbon PF07282.6 OAJ06421.1 - 2.5 7.8 6.1 4.8 6.9 0.3 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DUF3795 PF12675.2 OAJ06421.1 - 2.5 8.3 7.5 4.8 7.4 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) zf-UBR PF02207.15 OAJ06421.1 - 3.6 7.3 11.5 5.6 6.7 0.9 3.1 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Rpr2 PF04032.11 OAJ06421.1 - 4.7 7.1 11.1 2.1e+02 1.8 7.7 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-3CxxC PF13695.1 OAJ06421.1 - 8.3 6.7 9.5 2.4 8.4 2.2 2.4 1 1 1 2 2 2 0 Zinc-binding domain Tetraspannin PF00335.15 OAJ06422.1 - 0.002 17.4 9.0 0.012 14.9 6.3 1.9 1 1 0 1 1 1 1 Tetraspanin family DsbB PF02600.11 OAJ06422.1 - 0.16 11.7 6.8 0.023 14.5 1.5 1.9 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB DUF4234 PF14018.1 OAJ06422.1 - 0.64 9.7 3.4 4.5 7.0 0.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) DUF3040 PF11239.3 OAJ06422.1 - 4.5 7.4 7.0 10 6.2 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) zf-HIT PF04438.11 OAJ06424.1 - 1.9e-09 37.0 9.6 2.7e-09 36.4 6.6 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 OAJ06424.1 - 0.021 14.7 7.2 0.041 13.7 5.0 1.4 1 0 0 1 1 1 0 B-box zinc finger Tetraspannin PF00335.15 OAJ06425.1 - 5.1e-06 25.9 2.6 5.1e-06 25.9 1.8 2.0 1 1 1 2 2 2 1 Tetraspanin family Orbi_NS3 PF01616.11 OAJ06425.1 - 0.0079 15.1 0.0 0.24 10.3 0.0 2.2 1 1 1 2 2 2 1 Orbivirus NS3 DUF4234 PF14018.1 OAJ06425.1 - 0.057 13.1 0.4 0.69 9.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) TMEM223 PF14640.1 OAJ06425.1 - 0.14 12.1 0.5 0.31 10.9 0.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 223 Synaptobrevin PF00957.16 OAJ06425.1 - 0.18 11.4 0.5 0.38 10.3 0.2 1.7 1 1 0 1 1 1 0 Synaptobrevin DUF2207 PF09972.4 OAJ06425.1 - 0.21 10.1 2.0 3.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1469 PF07332.6 OAJ06426.1 - 0.0046 16.6 6.5 0.0079 15.9 4.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) DUF4131 PF13567.1 OAJ06426.1 - 0.014 14.8 1.1 0.016 14.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3573 PF12097.3 OAJ06426.1 - 0.015 13.9 0.0 0.018 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TBPIP PF07106.8 OAJ06426.1 - 0.092 12.2 0.4 0.11 11.9 0.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Allexi_40kDa PF05549.6 OAJ06426.1 - 0.14 11.4 0.5 0.18 11.0 0.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3535 PF12054.3 OAJ06427.1 - 2.2e-109 366.0 0.0 4.7e-108 361.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 OAJ06427.1 - 2.6e-69 233.3 0.0 4e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ06427.1 - 5.4e-12 45.4 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 OAJ06427.1 - 2.3e-09 36.5 31.1 0.036 14.1 0.2 11.0 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 OAJ06427.1 - 0.0028 17.8 27.8 0.0033 17.6 0.2 8.5 8 2 1 9 9 9 1 HEAT repeats HDA2-3 PF11496.3 OAJ06427.1 - 0.0046 15.8 0.0 0.0091 14.8 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Vac14_Fab1_bd PF12755.2 OAJ06427.1 - 0.027 14.8 0.0 0.29 11.5 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region CAP PF00188.21 OAJ06428.1 - 1.3e-22 80.5 2.6 2.4e-22 79.7 1.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cnd2 PF05786.9 OAJ06429.1 - 4.5e-139 465.1 7.1 3.6e-82 277.0 0.3 3.1 3 0 0 3 3 3 2 Condensin complex subunit 2 DUF4152 PF13680.1 OAJ06429.1 - 0.00088 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) Pkinase PF00069.20 OAJ06431.1 - 4.4e-35 121.0 0.0 6.6e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06431.1 - 4.2e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_E PF05680.7 OAJ06432.1 - 2.4e-22 78.6 0.1 2.6e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 OAJ06432.1 - 0.014 15.5 0.5 0.017 15.2 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) KIP1 PF07765.7 OAJ06432.1 - 0.024 14.4 0.5 0.036 13.9 0.3 1.2 1 0 0 1 1 1 0 KIP1-like protein LdpA_C PF12617.3 OAJ06432.1 - 0.034 13.3 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal ABC_trans_N PF14510.1 OAJ06432.1 - 0.087 12.9 0.3 0.12 12.5 0.2 1.5 1 1 0 1 1 1 0 ABC-transporter extracellular N-terminal NAD_Gly3P_dh_C PF07479.9 OAJ06433.1 - 2.3e-49 166.9 0.1 3.9e-49 166.2 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 OAJ06433.1 - 2e-47 160.8 0.0 4.4e-47 159.7 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 OAJ06433.1 - 9.7e-06 25.9 0.6 0.00014 22.2 0.4 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 OAJ06433.1 - 0.021 14.1 0.3 1.5 8.1 0.0 2.4 1 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF3375 PF11855.3 OAJ06433.1 - 0.073 11.8 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Complex1_30kDa PF00329.14 OAJ06434.1 - 2.1e-35 121.0 0.0 3.1e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit AhpC-TSA_2 PF13911.1 OAJ06435.1 - 1.8e-13 50.4 0.0 7e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 OAJ06435.1 - 2.3e-08 33.6 0.0 5.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 OAJ06435.1 - 1.5e-07 31.1 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.7 OAJ06435.1 - 0.034 13.6 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Pkinase PF00069.20 OAJ06436.1 - 2.7e-35 121.8 0.0 3.9e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06436.1 - 2.4e-22 79.2 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 OAJ06438.1 - 4.5e-64 215.3 0.4 4.5e-64 215.3 0.3 2.7 2 1 0 2 2 2 1 RIO1 family APH PF01636.18 OAJ06438.1 - 0.0079 15.9 1.4 1.8 8.2 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family NMD3 PF04981.8 OAJ06439.1 - 2.2e-76 256.0 0.5 3.1e-76 255.6 0.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 OAJ06439.1 - 0.0091 15.8 6.1 0.046 13.5 3.1 2.6 2 1 1 3 3 3 1 Double zinc ribbon Rpr2 PF04032.11 OAJ06439.1 - 0.75 9.7 3.3 3.1 7.7 2.3 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-dskA_traR PF01258.12 OAJ06439.1 - 7.9 6.3 6.4 0.76 9.5 0.1 2.6 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger CwfJ_C_1 PF04677.10 OAJ06440.1 - 2e-22 79.1 0.0 4.8e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 OAJ06440.1 - 3.5e-13 49.8 0.0 7.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 OAJ06440.1 - 1.7e-10 40.2 4.3 3.5e-06 26.3 0.7 2.8 2 0 0 2 2 2 2 Zinc knuckle CAP PF00188.21 OAJ06441.1 - 4.6e-22 78.8 2.7 7.4e-22 78.1 1.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 OAJ06442.1 - 1.2e-23 83.9 1.8 2.1e-23 83.1 1.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 OAJ06443.1 - 4.1e-21 75.7 1.8 6.6e-21 75.0 1.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NIF PF03031.13 OAJ06444.1 - 2e-48 164.0 0.0 1.2e-41 141.9 0.0 2.8 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Spc7_N PF15402.1 OAJ06444.1 - 0.95 7.3 17.5 1.3 6.9 12.1 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FLO_LFY PF01698.11 OAJ06444.1 - 1.8 7.2 7.9 2.6 6.8 5.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDK5_activator PF03261.10 OAJ06444.1 - 3.7 6.7 8.7 5.5 6.2 6.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SAGA-Tad1 PF12767.2 OAJ06444.1 - 3.9 7.0 14.1 5.7 6.5 9.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit BAF1_ABF1 PF04684.8 OAJ06444.1 - 5 5.8 16.2 7 5.3 11.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NARP1 PF12569.3 OAJ06444.1 - 8.8 4.9 8.5 12 4.5 5.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Homoserine_dh PF00742.14 OAJ06445.1 - 1.1e-45 155.4 0.0 1.7e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 OAJ06445.1 - 8.4e-15 55.1 0.1 1.7e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Alpha_adaptinC2 PF02883.15 OAJ06446.1 - 0.17 12.1 1.4 0.44 10.8 1.0 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain MIP PF00230.15 OAJ06447.1 - 3.5e-47 160.7 15.2 4.3e-47 160.4 10.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein TFIID_30kDa PF03540.8 OAJ06448.1 - 5.4e-26 90.1 0.0 9.5e-26 89.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.23 OAJ06448.1 - 7.2e-05 22.4 0.0 0.026 14.3 0.0 2.6 3 0 0 3 3 3 2 CBS domain PGK PF00162.14 OAJ06449.1 - 1.3e-151 504.5 2.6 1.5e-151 504.3 1.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NTF2 PF02136.15 OAJ06450.1 - 1.6e-33 115.5 0.3 1.7e-33 115.4 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.1 OAJ06450.1 - 0.025 14.5 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 OAJ06450.1 - 0.07 13.3 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) ABC2_membrane PF01061.19 OAJ06452.1 - 3.9e-36 124.1 20.0 3.9e-36 124.1 13.9 2.0 3 0 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ06452.1 - 3.6e-25 88.8 0.0 6.6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 OAJ06452.1 - 3.5e-09 37.0 0.1 4.7e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 OAJ06452.1 - 9.1e-06 24.9 25.8 2.3e-05 23.5 17.9 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 OAJ06452.1 - 0.00062 19.2 0.1 0.018 14.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ06452.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 OAJ06452.1 - 0.0091 16.8 0.0 0.017 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 OAJ06452.1 - 0.021 13.8 0.0 5.5 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 OAJ06452.1 - 0.021 14.3 0.1 0.07 12.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 OAJ06452.1 - 0.032 14.3 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 OAJ06452.1 - 0.035 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ06452.1 - 0.041 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAJ06452.1 - 0.042 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 OAJ06452.1 - 0.046 12.9 0.1 0.088 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 OAJ06452.1 - 0.085 12.5 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 OAJ06452.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 OAJ06452.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 OAJ06452.1 - 0.18 11.7 2.6 0.51 10.2 0.0 3.0 2 2 1 3 3 3 0 Putative exonuclease SbcCD, C subunit cobW PF02492.14 OAJ06452.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 OAJ06452.1 - 0.28 11.4 0.4 0.48 10.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain Tim44 PF04280.10 OAJ06453.1 - 1.9e-09 37.6 0.2 7.9e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 Tim44-like domain MCLC PF05934.6 OAJ06453.1 - 0.045 12.0 1.7 0.052 11.8 1.2 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) TelA PF05816.6 OAJ06453.1 - 0.089 11.4 0.1 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DivIC PF04977.10 OAJ06456.1 - 0.015 14.7 2.3 0.015 14.7 1.6 2.6 2 0 0 2 2 2 0 Septum formation initiator LEH PF07858.7 OAJ06456.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain EF1G PF00647.14 OAJ06463.1 - 2.7e-47 158.8 0.1 5.2e-47 157.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 OAJ06463.1 - 1.9e-12 46.9 0.0 5.5e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ06463.1 - 8.9e-11 41.8 0.4 6.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ06463.1 - 1.1e-09 37.9 0.0 2.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ06463.1 - 2.5e-07 30.8 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 OAJ06463.1 - 2.7e-07 31.0 0.0 6.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ06463.1 - 0.012 15.6 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 OAJ06463.1 - 0.73 10.2 10.1 1.8 9.0 7.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein EF1G PF00647.14 OAJ06464.1 - 6.6e-47 157.6 0.1 1.2e-46 156.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 OAJ06464.1 - 1.4e-11 44.2 0.0 3.9e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 OAJ06464.1 - 5.1e-10 39.3 0.2 3.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ06464.1 - 3.3e-09 36.4 0.0 6.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ06464.1 - 2.4e-08 34.3 0.0 6.6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ06464.1 - 0.00021 21.4 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 OAJ06464.1 - 0.26 11.7 7.8 0.57 10.6 5.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein ABC2_membrane PF01061.19 OAJ06465.1 - 2.4e-67 226.1 51.1 5.5e-37 126.9 13.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 OAJ06465.1 - 1.8e-36 125.4 0.0 2.3e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 OAJ06465.1 - 3.9e-21 74.6 0.0 3.9e-21 74.6 0.0 3.0 3 0 0 3 3 2 1 CDR ABC transporter AAA_25 PF13481.1 OAJ06465.1 - 4.4e-08 32.7 0.0 0.00012 21.5 0.1 3.4 3 0 0 3 3 3 1 AAA domain ABC_trans_N PF14510.1 OAJ06465.1 - 1.3e-06 28.3 0.2 4.1e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 OAJ06465.1 - 8.8e-06 25.1 1.1 0.04 13.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ06465.1 - 0.00066 18.8 0.1 0.037 13.2 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 OAJ06465.1 - 0.002 17.6 0.2 0.57 9.6 0.0 3.0 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 OAJ06465.1 - 0.002 18.2 0.3 1.2 9.2 0.3 3.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ06465.1 - 0.0038 18.0 0.0 0.13 13.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ06465.1 - 0.0038 17.2 4.2 0.2 11.6 0.9 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 OAJ06465.1 - 0.011 15.7 0.0 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 OAJ06465.1 - 0.013 15.1 5.5 0.7 9.5 0.2 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 OAJ06465.1 - 0.031 14.1 0.1 4.5 7.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 OAJ06465.1 - 0.048 13.9 0.5 0.49 10.7 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 OAJ06465.1 - 0.063 12.8 1.9 2 7.9 0.1 3.2 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.1 OAJ06465.1 - 0.074 13.0 0.4 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ06465.1 - 0.1 12.5 0.0 18 5.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 OAJ06465.1 - 0.11 12.6 0.0 30 4.8 0.1 2.8 2 0 0 2 2 2 0 RNA helicase cobW PF02492.14 OAJ06465.1 - 0.28 10.6 3.3 0.28 10.6 0.7 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 OAJ06465.1 - 6 6.5 5.1 12 5.5 0.4 2.9 3 0 0 3 3 3 0 NACHT domain RRM_1 PF00076.17 OAJ06466.1 - 1.1e-54 181.9 0.0 5.6e-18 64.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06466.1 - 9e-46 153.7 0.1 2.3e-14 53.1 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06466.1 - 4.2e-31 106.5 0.0 5.7e-09 35.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 OAJ06466.1 - 0.0023 17.6 1.5 0.27 11.0 0.0 3.9 3 1 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 OAJ06466.1 - 0.063 13.1 0.1 9.5 6.1 0.0 3.8 3 1 0 3 3 3 0 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ06466.1 - 0.068 12.9 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Clat_adaptor_s PF01217.15 OAJ06467.1 - 3.3e-09 36.6 0.0 4.6e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-RanBP PF00641.13 OAJ06469.1 - 2.2e-11 42.6 12.1 9.8e-07 27.7 0.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others NST1 PF13945.1 OAJ06470.1 - 1.3e-50 172.1 0.0 1.3e-50 172.1 0.0 7.7 6 2 1 7 7 7 2 Salt tolerance down-regulator Nsp1_C PF05064.8 OAJ06471.1 - 7.6e-21 73.9 0.0 2.5e-20 72.2 0.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region CENP-Q PF13094.1 OAJ06471.1 - 0.16 12.0 0.5 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.7 OAJ06471.1 - 1.6 8.5 4.5 15 5.3 0.5 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus eIF-5a PF01287.15 OAJ06472.1 - 1.3e-27 95.4 0.6 2e-27 94.9 0.4 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 OAJ06472.1 - 8.7e-05 22.0 0.6 0.0002 20.9 0.4 1.6 1 0 0 1 1 1 1 KOW motif Pil1 PF13805.1 OAJ06472.1 - 0.027 13.6 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 EFP_N PF08207.7 OAJ06472.1 - 0.043 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain NMO PF03060.10 OAJ06473.1 - 5e-45 154.0 0.5 8.9e-28 97.3 0.1 2.8 2 2 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 OAJ06473.1 - 0.0035 16.2 0.9 0.0088 14.9 0.0 2.0 3 0 0 3 3 3 1 FMN-dependent dehydrogenase Abhydrolase_6 PF12697.2 OAJ06473.1 - 0.036 13.9 5.1 0.49 10.2 0.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family RabGAP-TBC PF00566.13 OAJ06474.1 - 3.3e-48 164.0 0.0 5.2e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 OAJ06474.1 - 8.6e-08 31.5 0.0 2e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain IGPS PF00218.16 OAJ06475.1 - 1.3e-85 286.5 0.0 8e-85 283.9 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 OAJ06475.1 - 5.3e-45 153.2 0.0 8.9e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 OAJ06475.1 - 8e-39 133.2 0.0 1.7e-35 122.3 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 OAJ06475.1 - 6.2e-06 25.8 0.1 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 NUDE_C PF04880.8 OAJ06476.1 - 0.07 13.4 2.9 0.14 12.5 2.0 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Phage_lysis PF03245.8 OAJ06476.1 - 0.081 12.9 5.3 0.15 12.0 3.6 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein IncA PF04156.9 OAJ06476.1 - 0.79 9.2 4.8 1.4 8.5 3.3 1.3 1 0 0 1 1 1 0 IncA protein DUF1180 PF06679.7 OAJ06476.1 - 0.94 9.3 0.0 0.94 9.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) DUF972 PF06156.8 OAJ06476.1 - 0.96 9.8 4.4 2.1 8.7 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1875 PF08961.5 OAJ06476.1 - 1.8 7.7 9.6 7.1 5.8 6.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1875) APG6 PF04111.7 OAJ06476.1 - 1.9 7.4 9.1 2.8 6.8 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 OAJ06476.1 - 2.5 7.5 6.1 4.2 6.7 4.2 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1682 PF07946.9 OAJ06476.1 - 3.2 6.5 7.7 4.6 5.9 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF904 PF06005.7 OAJ06476.1 - 9.3 6.6 17.3 1.4 9.3 7.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Nuc_sug_transp PF04142.10 OAJ06478.1 - 5.2e-07 29.0 0.3 8.2e-07 28.3 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 OAJ06478.1 - 1.5e-05 25.0 3.2 1.5e-05 25.0 2.3 3.6 3 1 0 3 3 3 1 EamA-like transporter family CoxIIa PF08113.6 OAJ06478.1 - 0.047 13.4 0.9 0.17 11.6 0.6 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IIa family CitMHS PF03600.11 OAJ06478.1 - 0.065 11.8 9.7 0.13 10.8 6.7 1.4 1 0 0 1 1 1 0 Citrate transporter TPT PF03151.11 OAJ06478.1 - 1 9.0 15.1 0.059 13.0 0.8 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family LrgB PF04172.11 OAJ06479.1 - 1.2e-23 83.3 7.0 4.2e-23 81.6 4.9 2.0 1 1 0 1 1 1 1 LrgB-like family MFS_2 PF13347.1 OAJ06480.1 - 6.3e-10 38.0 1.6 6.3e-10 38.0 1.1 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein DUF89 PF01937.14 OAJ06481.1 - 6.7e-110 367.2 0.1 7.6e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NaeI PF09126.5 OAJ06481.1 - 0.064 11.8 0.1 1.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease NaeI RRM_6 PF14259.1 OAJ06482.1 - 1.4e-08 34.6 0.0 4.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06482.1 - 2.4e-08 33.6 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 OAJ06482.1 - 1.8e-07 30.6 2.4 3.4e-07 29.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 OAJ06482.1 - 9.9e-07 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 OAJ06482.1 - 7.8e-05 22.3 0.0 0.00078 19.1 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 OAJ06482.1 - 0.00031 20.3 1.1 0.00053 19.6 0.1 1.8 2 0 0 2 2 2 1 Calcipressin RRM_1 PF00076.17 OAJ06482.1 - 0.00074 19.1 0.1 0.0021 17.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ06482.1 - 0.013 15.3 1.8 0.033 14.0 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif Seryl_tRNA_N PF02403.17 OAJ06482.1 - 6 6.9 9.8 0.2 11.7 2.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ASF1_hist_chap PF04729.8 OAJ06483.1 - 4.3e-57 192.0 1.6 5e-56 188.6 1.1 1.9 1 1 0 1 1 1 1 ASF1 like histone chaperone Response_reg PF00072.19 OAJ06484.1 - 8.3e-23 80.5 0.1 3.2e-16 59.3 0.1 3.1 3 0 0 3 3 3 2 Response regulator receiver domain RRP14 PF15459.1 OAJ06484.1 - 0.27 11.3 0.0 0.62 10.1 0.0 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 HALZ PF02183.13 OAJ06485.1 - 0.00064 19.3 7.9 0.0052 16.4 5.2 2.6 1 1 0 1 1 1 1 Homeobox associated leucine zipper Occludin_ELL PF07303.8 OAJ06485.1 - 0.0049 17.5 2.7 0.0049 17.5 1.9 2.0 1 1 0 1 1 1 1 Occludin homology domain IncA PF04156.9 OAJ06485.1 - 0.02 14.5 1.5 0.026 14.1 1.0 1.3 1 0 0 1 1 1 0 IncA protein DUF4337 PF14235.1 OAJ06485.1 - 0.04 13.7 2.7 0.085 12.6 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP-synt_D PF01813.12 OAJ06485.1 - 0.045 13.2 3.4 0.07 12.6 2.4 1.3 1 0 0 1 1 1 0 ATP synthase subunit D APG6 PF04111.7 OAJ06485.1 - 0.058 12.4 4.3 0.071 12.1 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 OAJ06485.1 - 0.16 12.3 9.3 0.021 15.1 3.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 OAJ06485.1 - 0.23 10.3 8.3 0.29 10.0 5.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 OAJ06485.1 - 0.67 9.4 6.8 0.42 10.1 1.9 2.4 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.13 OAJ06485.1 - 2.5 8.1 6.6 10 6.1 1.4 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF641 PF04859.7 OAJ06485.1 - 6.3 6.5 9.0 0.28 10.9 2.2 2.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) ABC1 PF03109.11 OAJ06486.1 - 9.6e-25 86.8 0.0 1.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.4 OAJ06486.1 - 6.9e-18 63.8 1.4 1.7e-17 62.5 1.0 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Asp_protease_2 PF13650.1 OAJ06487.1 - 0.00042 20.7 0.2 0.00077 19.9 0.1 1.7 1 1 0 1 1 1 1 Aspartyl protease RVP PF00077.15 OAJ06487.1 - 0.0015 18.4 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3584 PF12128.3 OAJ06488.1 - 0.011 13.1 3.5 0.013 12.8 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rab3-GTPase_cat PF13890.1 OAJ06488.1 - 0.043 13.1 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit IncA PF04156.9 OAJ06488.1 - 0.062 12.8 1.9 0.093 12.3 1.3 1.4 1 1 0 1 1 1 0 IncA protein Cortex-I_coil PF09304.5 OAJ06488.1 - 0.18 11.8 6.4 0.58 10.2 4.4 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil HALZ PF02183.13 OAJ06488.1 - 0.28 10.9 4.6 0.15 11.7 0.7 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 OAJ06488.1 - 0.71 10.2 3.8 3.9 7.8 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) LSM PF01423.17 OAJ06490.1 - 9.5e-21 73.1 0.1 1.1e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ06490.1 - 0.00051 19.9 0.0 0.0006 19.6 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Sua5_yciO_yrdC PF01300.13 OAJ06491.1 - 1.4e-46 157.9 0.0 3.1e-46 156.8 0.0 1.6 1 1 0 1 1 1 1 Telomere recombination NUDIX PF00293.23 OAJ06492.1 - 7.9e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain OPA3 PF07047.7 OAJ06493.1 - 5.7e-34 116.7 3.4 5.7e-34 116.7 2.4 1.8 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) FtsK_SpoIIIE PF01580.13 OAJ06493.1 - 0.063 12.7 1.1 0.14 11.6 0.7 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pyr_redox_dim PF02852.17 OAJ06495.1 - 2.4e-41 140.1 0.1 5.9e-41 138.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 OAJ06495.1 - 1.9e-38 132.3 21.0 1.9e-36 125.8 13.1 3.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ06495.1 - 1.2e-20 73.6 11.3 5.1e-18 65.2 1.3 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 OAJ06495.1 - 4.3e-12 45.8 4.8 1.3e-11 44.3 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 OAJ06495.1 - 8.2e-11 42.3 0.4 1.1e-06 28.8 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 OAJ06495.1 - 8.7e-10 38.0 10.2 2.8e-09 36.3 2.1 2.8 2 2 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 OAJ06495.1 - 1.4e-08 34.5 4.2 0.00014 21.8 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ06495.1 - 1.9e-07 30.2 2.2 1.9e-07 30.2 1.5 3.8 3 1 2 5 5 5 1 FAD binding domain HI0933_like PF03486.9 OAJ06495.1 - 1.3e-06 27.2 13.2 8.6e-05 21.1 0.8 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 OAJ06495.1 - 3.1e-06 26.3 0.6 0.065 12.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 OAJ06495.1 - 3.5e-05 23.0 7.4 4.5e-05 22.6 0.1 2.8 2 1 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.16 OAJ06495.1 - 0.00051 19.6 2.4 0.096 12.2 0.1 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 OAJ06495.1 - 0.00057 19.0 11.9 0.018 14.0 0.8 3.4 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 OAJ06495.1 - 0.0045 15.9 20.2 0.0089 14.9 1.5 3.8 2 2 2 4 4 4 2 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.14 OAJ06495.1 - 0.019 14.0 0.3 0.054 12.5 0.2 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 OAJ06495.1 - 0.084 11.7 0.1 0.084 11.7 0.1 2.5 3 1 0 3 3 3 0 Lycopene cyclase protein RabGAP-TBC PF00566.13 OAJ06499.1 - 1.9e-50 171.3 0.0 2.5e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.23 OAJ06499.1 - 0.0071 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ06499.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain GTP_EFTU PF00009.22 OAJ06500.1 - 1.3e-31 109.4 0.1 2.6e-24 85.7 0.6 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.3 OAJ06500.1 - 1.1e-21 76.7 0.1 2.1e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 OAJ06500.1 - 2.4e-06 27.4 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 OAJ06500.1 - 5.7e-05 23.1 0.4 0.23 11.5 0.2 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Miro PF08477.8 OAJ06500.1 - 0.029 14.8 0.1 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein SRPRB PF09439.5 OAJ06500.1 - 0.052 12.7 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IF2_N PF04760.10 OAJ06500.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mem_trans PF03547.13 OAJ06500.1 - 0.19 9.9 0.5 0.32 9.2 0.4 1.4 1 0 0 1 1 1 0 Membrane transport protein MobB PF03205.9 OAJ06500.1 - 0.2 11.3 1.3 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PAT1 PF09770.4 OAJ06500.1 - 0.66 8.1 58.2 1.6 6.9 40.3 1.6 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 OAJ06500.1 - 3.2 5.9 22.8 0.0032 15.8 7.6 2.0 2 0 0 2 2 2 0 Transmembrane protein HLH PF00010.21 OAJ06501.1 - 2.9e-12 46.0 0.0 5.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 OAJ06501.1 - 6.6 4.8 28.0 9.5 4.3 19.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RhoGEF PF00621.15 OAJ06502.1 - 5.2e-39 133.9 0.3 8.2e-39 133.3 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 OAJ06502.1 - 8.6e-32 109.7 0.0 1.4e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 OAJ06502.1 - 8.7e-21 73.7 0.1 3.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.19 OAJ06502.1 - 1.1e-09 37.8 0.1 2.1e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 OAJ06502.1 - 0.0086 16.2 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 PH domain RNA_pol PF00940.14 OAJ06503.1 - 2.7e-154 513.5 0.0 3.9e-154 513.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 OAJ06503.1 - 5.9e-69 232.7 0.0 1e-68 231.9 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal CPDase PF07823.6 OAJ06505.1 - 3.7e-30 104.8 0.0 4.4e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 OAJ06505.1 - 3e-06 27.0 0.2 5.7e-06 26.1 0.2 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily HemN_C PF06969.11 OAJ06505.1 - 0.0072 16.3 0.2 0.057 13.4 0.2 2.2 1 1 0 1 1 1 1 HemN C-terminal domain DUF3349 PF11829.3 OAJ06505.1 - 0.031 14.7 0.0 0.078 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HTH_22 PF13309.1 OAJ06505.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain LigT_PEase PF02834.11 OAJ06505.1 - 0.11 12.4 0.1 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 LigT like Phosphoesterase Sec1 PF00995.18 OAJ06506.1 - 4.9e-147 490.9 0.0 5.7e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-primase PF09329.6 OAJ06507.1 - 1.2e-09 37.5 1.1 2.2e-09 36.7 0.8 1.4 1 0 0 1 1 1 1 Primase zinc finger Exo_endo_phos PF03372.18 OAJ06508.1 - 4.5e-07 30.0 0.1 7.7e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_25 PF01183.15 OAJ06509.1 - 7.2e-48 162.8 5.8 8.3e-48 162.5 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RRM_1 PF00076.17 OAJ06511.1 - 1.8e-12 46.7 0.0 2.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06511.1 - 3.2e-09 36.6 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06511.1 - 1.4e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 OAJ06511.1 - 0.00013 21.6 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nuclease_act PF08133.6 OAJ06512.1 - 0.21 11.0 0.9 0.4 10.2 0.7 1.4 1 0 0 1 1 1 0 Anticodon nuclease activator family DNA_pol_phi PF04931.8 OAJ06513.1 - 1.6e-30 105.6 38.0 3.3e-23 81.4 21.6 3.3 3 1 0 3 3 3 2 DNA polymerase phi DUF2457 PF10446.4 OAJ06513.1 - 0.022 13.4 23.8 0.11 11.1 16.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 OAJ06513.1 - 0.75 7.8 16.3 1.7 6.6 11.3 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Myb_DNA-binding PF00249.26 OAJ06514.1 - 0.05 13.6 0.1 0.18 11.9 0.1 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Transglut_core3 PF13471.1 OAJ06515.1 - 0.036 13.8 0.9 0.13 12.0 0.6 2.0 1 1 0 1 1 1 0 Transglutaminase-like superfamily Myb_DNA-bind_4 PF13837.1 OAJ06515.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Abhydrolase_4 PF08386.5 OAJ06517.1 - 8.8e-16 57.6 0.0 1.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 OAJ06517.1 - 1.1e-12 48.0 0.0 3.8e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ06517.1 - 7.4e-08 32.5 0.0 2e-06 27.8 0.0 2.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ06517.1 - 5.4e-05 22.9 0.0 0.00057 19.6 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family SET PF00856.23 OAJ06518.1 - 4.9e-24 85.4 3.1 6.1e-23 81.9 0.2 2.9 2 1 0 2 2 2 1 SET domain SRI PF08236.6 OAJ06518.1 - 2.5e-15 56.1 4.6 2.5e-15 56.1 3.2 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 OAJ06518.1 - 0.033 13.7 0.0 0.097 12.1 0.0 1.8 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DUF4603 PF15376.1 OAJ06518.1 - 0.062 10.5 21.8 0.089 9.9 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Autophagy_act_C PF03987.10 OAJ06519.1 - 5.7e-11 42.4 1.5 2.7e-10 40.2 1.0 2.2 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3473 PF11959.3 OAJ06519.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) MFS_1 PF07690.11 OAJ06524.1 - 1.8e-29 102.5 26.2 1.8e-29 102.5 18.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06524.1 - 1.9e-22 79.5 21.5 5.2e-18 64.8 4.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Nup188 PF10487.4 OAJ06525.1 - 0.26 9.1 0.2 1.1 7.0 0.0 2.0 3 0 0 3 3 3 0 Nucleoporin subcomplex protein binding to Pom34 SNF2_N PF00176.18 OAJ06526.1 - 3.9e-77 258.9 0.1 7.7e-77 258.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ06526.1 - 2.9e-18 65.4 0.0 4.2e-17 61.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 OAJ06526.1 - 3e-18 65.3 9.7 3e-18 65.3 6.7 2.7 3 0 0 3 3 3 1 HSA Bromodomain PF00439.20 OAJ06526.1 - 5.7e-18 64.6 0.5 1.5e-17 63.2 0.3 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 OAJ06526.1 - 4.3e-14 52.4 1.7 4.3e-14 52.4 1.2 3.4 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 OAJ06526.1 - 2.8e-11 42.6 3.3 7.2e-11 41.3 2.3 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.10 OAJ06526.1 - 2.5e-05 24.1 2.0 0.001 18.9 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Cpn60_TCP1 PF00118.19 OAJ06527.1 - 4.8e-141 470.6 11.2 5.9e-141 470.3 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 OAJ06527.1 - 0.0015 17.7 0.1 0.0051 16.0 0.0 1.9 2 0 0 2 2 2 1 Telomere recombination zf-C2H2 PF00096.21 OAJ06528.1 - 0.075 13.3 5.3 0.21 11.9 3.7 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_23 PF13489.1 OAJ06529.1 - 8.7e-06 25.5 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ06529.1 - 0.2 12.1 0.0 2.1 8.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Nop14 PF04147.7 OAJ06529.1 - 0.24 9.2 2.9 0.46 8.3 2.0 1.4 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 OAJ06529.1 - 5.5 6.1 4.4 9.9 5.3 3.0 1.3 1 0 0 1 1 1 0 NOA36 protein APG6 PF04111.7 OAJ06530.1 - 3.5 6.6 13.5 6.9 5.6 9.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF465 PF04325.8 OAJ06530.1 - 5.6 6.7 12.7 0.086 12.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Vps53_N PF04100.7 OAJ06532.1 - 5.9e-83 278.7 0.3 9.3e-83 278.1 0.2 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2580 PF10824.3 OAJ06532.1 - 0.006 16.9 0.1 0.83 10.0 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2580) DUF2450 PF10475.4 OAJ06532.1 - 0.016 14.1 5.1 0.032 13.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 OAJ06532.1 - 0.072 12.8 2.8 0.19 11.4 1.9 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 Na_H_Exchanger PF00999.16 OAJ06534.1 - 2.4e-37 128.3 24.2 3.3e-37 127.9 16.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family HSF_DNA-bind PF00447.12 OAJ06535.1 - 2.9e-34 117.3 0.0 2.9e-34 117.3 0.0 2.9 3 0 0 3 3 3 1 HSF-type DNA-binding FA_desaturase PF00487.19 OAJ06536.1 - 1.7e-27 96.4 21.8 5.3e-27 94.8 15.1 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 OAJ06536.1 - 0.099 12.6 0.1 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Metallophos PF00149.23 OAJ06537.1 - 2.2e-30 105.5 0.0 1.4e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPR_11 PF13414.1 OAJ06537.1 - 1.1e-18 66.6 5.3 2e-13 49.7 1.4 2.8 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 OAJ06537.1 - 6.1e-13 47.7 5.4 2.3e-06 26.9 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat PPP5 PF08321.7 OAJ06537.1 - 1.3e-08 34.7 0.0 6e-05 22.9 0.0 2.4 1 1 1 2 2 2 2 PPP5 TPR repeat region TPR_2 PF07719.12 OAJ06537.1 - 8.1e-08 31.6 8.0 0.0025 17.5 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ06537.1 - 0.001 18.8 0.3 0.0054 16.5 0.2 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ06537.1 - 0.002 18.1 0.8 0.12 12.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ06537.1 - 0.0065 17.0 2.3 1.7 9.5 0.1 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 OAJ06537.1 - 0.007 15.4 0.3 0.68 8.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ06537.1 - 0.022 15.4 2.0 0.17 12.5 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RAI1 PF08652.6 OAJ06538.1 - 2.2e-17 62.6 0.0 4.3e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease adh_short PF00106.20 OAJ06539.1 - 3.5e-30 105.0 0.6 7.3e-30 104.0 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ06539.1 - 1.5e-14 54.0 1.2 7e-13 48.6 0.6 2.9 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 OAJ06539.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 OAJ06539.1 - 1.3e-05 24.7 0.0 0.00028 20.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ06539.1 - 5.6e-05 23.2 0.3 0.00033 20.7 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ06539.1 - 7.5e-05 21.5 0.1 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ06539.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 OAJ06539.1 - 0.053 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Asp PF00026.18 OAJ06540.1 - 7e-64 216.0 0.2 9e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ06540.1 - 4.7e-07 29.8 0.1 1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 OAJ06540.1 - 6.6e-05 23.3 2.0 0.042 14.3 0.0 3.8 4 1 1 5 5 5 2 Aspartyl protease ADIP PF11559.3 OAJ06541.1 - 1.3e-19 70.5 4.3 1.3e-19 70.5 3.0 2.7 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 OAJ06541.1 - 0.25 9.0 16.4 0.015 13.0 5.3 2.3 3 0 0 3 3 3 0 Myosin tail APG6 PF04111.7 OAJ06541.1 - 0.58 9.1 8.4 6.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2229 PF09989.4 OAJ06541.1 - 2 7.8 3.9 0.92 8.9 0.2 2.0 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2570 PF10828.3 OAJ06541.1 - 3.1 7.4 6.8 1.2 8.8 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) ERM PF00769.14 OAJ06541.1 - 7.4 6.0 18.9 0.032 13.7 5.6 2.4 3 0 0 3 3 3 0 Ezrin/radixin/moesin family DUF972 PF06156.8 OAJ06541.1 - 8.3 6.8 9.9 17 5.7 2.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Ada_Zn_binding PF02805.11 OAJ06542.1 - 2e-20 72.1 8.0 4.2e-20 71.1 5.6 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 OAJ06542.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family RES PF08808.6 OAJ06543.1 - 0.017 15.2 0.3 0.019 15.0 0.2 1.0 1 0 0 1 1 1 0 RES domain LsmAD PF06741.8 OAJ06544.1 - 1.4e-22 79.5 0.4 3.5e-22 78.2 0.3 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 OAJ06544.1 - 7.8e-11 41.7 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Dala_Dala_lig_N PF01820.16 OAJ06544.1 - 0.059 13.6 0.4 0.21 11.8 0.3 1.9 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus L31 PF09784.4 OAJ06545.1 - 9.1e-42 141.3 1.0 1e-41 141.1 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Exo_endo_phos PF03372.18 OAJ06547.1 - 5.7e-20 72.2 0.0 8.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ06547.1 - 0.0065 16.0 0.0 0.042 13.4 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Adeno_VII PF03228.9 OAJ06547.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.6 2 1 0 2 2 2 0 Adenoviral core protein VII OTU PF02338.14 OAJ06548.1 - 4.9e-10 40.0 0.0 8.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease COesterase PF00135.23 OAJ06549.1 - 4.8e-77 259.8 0.0 6.2e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ06549.1 - 1.6e-07 31.1 0.7 2.3e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold AAA PF00004.24 OAJ06550.1 - 1.6e-13 50.9 0.0 4.1e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 OAJ06550.1 - 3.7e-07 29.2 0.2 0.021 13.5 0.0 3.0 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 OAJ06550.1 - 1.7e-05 24.0 0.0 3.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 OAJ06550.1 - 5.8e-05 23.9 0.1 0.00029 21.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 OAJ06550.1 - 7.5e-05 22.4 0.6 0.00032 20.3 0.0 2.4 3 0 0 3 3 2 1 Part of AAA domain AAA_14 PF13173.1 OAJ06550.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 OAJ06550.1 - 0.00047 20.1 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 OAJ06550.1 - 0.0034 17.5 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ06550.1 - 0.0038 17.2 4.4 0.2 11.6 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 OAJ06550.1 - 0.0077 16.1 0.0 0.064 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ06550.1 - 0.028 14.7 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ06550.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 OAJ06550.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ06550.1 - 0.049 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 OAJ06550.1 - 0.076 13.3 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 OAJ06550.1 - 0.13 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 OAJ06550.1 - 0.19 11.4 0.1 0.58 9.8 0.1 1.8 1 1 1 2 2 2 0 NTPase DUF258 PF03193.11 OAJ06550.1 - 0.22 10.7 0.0 0.46 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1752 PF08550.5 OAJ06551.1 - 2.2e-10 39.9 3.9 4.7e-10 38.8 2.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GATA PF00320.22 OAJ06552.1 - 2e-13 49.3 3.4 4.2e-13 48.3 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 OAJ06552.1 - 2.2e-10 40.3 0.0 2.2e-10 40.3 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_3 PF08447.6 OAJ06552.1 - 2.5e-06 27.5 1.6 5.4e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 OAJ06552.1 - 3.5e-05 24.1 1.2 8.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 OAJ06552.1 - 0.00093 19.2 1.4 0.0045 17.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold TF_Zn_Ribbon PF08271.7 OAJ06552.1 - 0.069 12.4 0.5 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zf-DHHC PF01529.15 OAJ06552.1 - 0.24 10.7 3.9 6.3 6.1 0.7 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2284 PF10050.4 OAJ06552.1 - 3.2 7.3 4.7 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Ycf1 PF05758.7 OAJ06552.1 - 5.6 4.5 12.7 1.8 6.1 1.8 2.0 2 0 0 2 2 2 0 Ycf1 AAA_23 PF13476.1 OAJ06552.1 - 6.7 6.9 17.7 0.038 14.3 0.5 2.4 2 0 0 2 2 2 0 AAA domain DUF383 PF04063.9 OAJ06553.1 - 1.7e-57 194.1 0.0 2.3e-56 190.3 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 OAJ06553.1 - 2.2e-18 65.5 1.1 4.8e-18 64.4 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) AAA_18 PF13238.1 OAJ06554.1 - 1.9e-21 76.7 0.0 3.6e-21 75.8 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ06554.1 - 6.3e-09 36.6 0.0 1.3e-08 35.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ06554.1 - 0.0022 17.8 0.1 0.35 10.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain E_Pc_C PF06752.7 OAJ06554.1 - 0.0094 15.4 3.8 0.038 13.5 0.1 2.1 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus AAA_28 PF13521.1 OAJ06554.1 - 0.012 15.5 0.7 0.031 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 OAJ06554.1 - 0.038 13.1 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 OAJ06554.1 - 0.048 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ADK PF00406.17 OAJ06554.1 - 0.051 13.4 0.1 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_16 PF13191.1 OAJ06554.1 - 0.072 13.0 1.2 0.25 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 OAJ06554.1 - 0.12 12.5 0.7 0.29 11.3 0.1 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 OAJ06554.1 - 0.12 11.7 0.1 0.33 10.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 OAJ06554.1 - 0.16 11.5 0.2 0.35 10.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 OAJ06554.1 - 0.55 9.6 2.5 0.82 9.0 0.1 2.1 3 0 0 3 3 3 0 AAA-like domain SR-25 PF10500.4 OAJ06554.1 - 3.4 7.0 5.5 0.35 10.3 0.9 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Exo_endo_phos PF03372.18 OAJ06555.1 - 5.3e-20 72.4 0.5 1.5e-18 67.6 0.0 2.2 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 OAJ06555.1 - 5.5e-12 45.3 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 OAJ06555.1 - 2e-05 24.4 2.7 0.00021 21.1 1.9 2.3 1 1 0 1 1 1 1 GRF zinc finger DUF3808 PF10300.4 OAJ06556.1 - 3.6e-76 256.6 0.0 6.5e-76 255.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.15 OAJ06556.1 - 1.8e-31 108.8 0.0 3.2e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 OAJ06556.1 - 3.3e-12 46.3 0.4 9.3e-12 44.8 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 OAJ06556.1 - 4.2e-12 46.1 0.1 2.7e-11 43.6 0.0 2.2 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain TPR_11 PF13414.1 OAJ06556.1 - 0.0046 16.5 9.9 0.066 12.8 2.3 3.6 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 OAJ06556.1 - 0.17 12.5 4.3 5.3 7.9 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ06556.1 - 0.39 10.3 7.3 0.91 9.2 0.9 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ06556.1 - 1.1 9.4 15.0 20 5.3 1.2 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ06556.1 - 2.1 8.3 11.9 0.33 10.9 2.2 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ06556.1 - 8.4 6.4 8.1 11 6.0 0.6 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.19 OAJ06557.1 - 9.8e-137 456.4 11.9 7.8e-88 295.2 3.4 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family RGS PF00615.14 OAJ06558.1 - 2.3e-12 47.0 0.0 2.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Sdh_cyt PF01127.17 OAJ06559.1 - 6e-24 84.1 3.7 9.1e-24 83.6 2.6 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF3450 PF11932.3 OAJ06559.1 - 0.04 13.1 0.3 0.056 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) His_Phos_1 PF00300.17 OAJ06560.1 - 1.2e-14 54.7 0.0 2.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Retrotrans_gag PF03732.12 OAJ06563.1 - 0.04 13.9 0.1 0.098 12.7 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein DGF-1_C PF11040.3 OAJ06563.1 - 7.8 6.4 10.4 1.1 9.1 0.0 3.3 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Transket_pyr PF02779.19 OAJ06565.1 - 5.5e-48 162.8 0.0 1.1e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ06565.1 - 2.7e-39 133.9 0.0 7.9e-39 132.4 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain rve PF00665.21 OAJ06566.1 - 9.3e-14 51.5 0.0 3.4e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain PRP1_N PF06424.7 OAJ06567.1 - 2.1 8.6 5.6 3.6 7.9 3.8 1.5 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal HTH_Tnp_Tc5 PF03221.11 OAJ06568.1 - 1e-05 25.2 0.6 1.9e-05 24.3 0.2 1.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 OAJ06568.1 - 0.0014 17.7 0.0 0.0028 16.8 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease Myb_DNA-bind_3 PF12776.2 OAJ06569.1 - 9.1e-05 23.0 0.1 0.00018 22.0 0.1 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ06569.1 - 0.017 15.2 2.6 0.035 14.2 1.8 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain MAPEG PF01124.13 OAJ06570.1 - 1.3e-24 86.2 2.5 1.5e-24 86.0 1.8 1.0 1 0 0 1 1 1 1 MAPEG family MFS_1 PF07690.11 OAJ06571.1 - 1.7e-36 125.6 12.4 2.5e-36 125.1 8.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06571.1 - 3.2e-08 32.6 3.5 3.2e-08 32.6 2.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 OAJ06571.1 - 0.00047 18.4 1.1 0.00086 17.6 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 OAJ06571.1 - 0.83 7.6 10.2 0.064 11.3 1.1 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector Glyco_hydro_18 PF00704.23 OAJ06572.1 - 3.5e-88 296.3 0.6 4.4e-88 296.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF202 PF02656.10 OAJ06573.1 - 1.2e-18 67.0 9.9 1.6e-18 66.6 3.1 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF2157 PF09925.4 OAJ06573.1 - 0.1 12.1 3.7 0.96 9.0 0.4 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Nitrate_red_del PF02613.10 OAJ06573.1 - 0.13 12.0 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Nitrate reductase delta subunit ACC_epsilon PF13822.1 OAJ06573.1 - 1.4 9.2 4.9 0.74 10.2 0.8 2.2 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF2393 PF09624.5 OAJ06574.1 - 0.063 12.8 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) KTI12 PF08433.5 OAJ06577.1 - 1.6e-53 181.6 0.0 2.5e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 OAJ06577.1 - 7.8e-10 38.7 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ06577.1 - 0.0005 20.3 0.0 0.0057 16.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mtr2 PF10429.4 OAJ06578.1 - 0.0041 16.9 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Na_H_Exchanger PF00999.16 OAJ06585.1 - 3.6e-60 203.4 20.8 4.6e-60 203.1 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family IFT46_B_C PF12317.3 OAJ06585.1 - 0.086 12.1 0.4 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Mem_trans PF03547.13 OAJ06587.1 - 1.1e-41 142.4 2.0 3.7e-38 130.8 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein TFIIE-A_C-term PF11521.3 OAJ06588.1 - 0.019 14.8 2.1 0.019 14.8 1.4 3.7 4 1 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha TFIIA PF03153.8 OAJ06588.1 - 6.3 6.5 21.6 5.9 6.6 4.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.5 OAJ06588.1 - 6.3 7.1 16.6 1.3 9.3 5.0 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain FF PF01846.14 OAJ06589.1 - 2.6e-20 72.1 13.6 2.8e-07 30.3 0.5 5.8 4 2 0 4 4 4 4 FF domain Oxysterol_BP PF01237.13 OAJ06590.1 - 1e-112 376.1 0.8 5.3e-112 373.8 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 OAJ06590.1 - 4e-16 58.8 0.0 7.8e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ06590.1 - 0.00015 21.8 0.0 0.00043 20.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 OAJ06590.1 - 0.0075 16.5 0.7 0.04 14.1 0.5 2.2 1 1 1 2 2 2 1 Pleckstrin homology domain DUF3752 PF12572.3 OAJ06592.1 - 7.9e-08 32.5 45.6 1.8e-07 31.3 16.7 4.0 2 1 2 4 4 4 2 Protein of unknown function (DUF3752) PALP PF00291.20 OAJ06593.1 - 5e-76 255.8 0.1 1e-75 254.8 0.1 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 OAJ06593.1 - 4.8e-23 80.5 0.2 1.4e-12 47.0 0.0 4.6 4 1 1 5 5 5 3 C-terminal regulatory domain of Threonine dehydratase Sec15 PF04091.7 OAJ06594.1 - 2.1e-73 247.3 0.0 2.8e-72 243.6 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.9 OAJ06594.1 - 5.7e-05 22.7 0.2 5.7e-05 22.7 0.1 2.8 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 OAJ06594.1 - 0.00025 20.8 0.6 0.0011 18.7 0.2 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 OAJ06594.1 - 0.00046 19.9 0.1 0.0042 16.9 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 OAJ06594.1 - 0.0022 17.9 3.9 0.01 15.8 0.1 3.4 3 1 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.6 OAJ06594.1 - 0.0053 16.6 3.9 0.0059 16.4 0.5 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 GFO_IDH_MocA_C PF02894.12 OAJ06594.1 - 0.15 11.8 0.6 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain RRM_1 PF00076.17 OAJ06595.1 - 5.4e-38 128.4 0.0 1.4e-16 59.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06595.1 - 1.5e-23 82.5 0.0 3.1e-09 36.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06595.1 - 3.5e-07 29.9 0.0 0.00089 19.0 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ06595.1 - 0.0037 17.0 3.7 0.82 9.5 0.0 3.6 2 1 0 2 2 2 1 RNA binding motif CDC45 PF02724.9 OAJ06595.1 - 0.015 13.4 17.4 0.032 12.2 12.1 1.5 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 OAJ06595.1 - 0.034 12.7 7.9 0.058 12.0 5.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 OAJ06595.1 - 0.11 10.4 31.2 0.19 9.6 21.6 1.3 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 OAJ06595.1 - 0.23 9.1 1.6 0.32 8.6 1.1 1.3 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 OAJ06595.1 - 0.24 9.8 27.7 0.53 8.7 19.2 1.5 1 0 0 1 1 1 0 Daxx Family TP2 PF01254.13 OAJ06595.1 - 0.81 10.0 5.0 3.3 8.0 3.5 2.0 1 0 0 1 1 1 0 Nuclear transition protein 2 Cwf_Cwc_15 PF04889.7 OAJ06595.1 - 1.4 8.5 34.0 0.049 13.3 18.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.2 OAJ06595.1 - 6.4 4.3 6.7 9.2 3.8 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 OAJ06595.1 - 7.2 5.7 20.4 14 4.8 14.1 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2036 PF09724.4 OAJ06596.1 - 5.2e-51 173.7 0.0 6.8e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Glyco_hydro_30 PF02055.11 OAJ06597.1 - 7.7e-19 67.2 2.6 3.5e-18 65.1 1.8 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Herpes_US9 PF06072.6 OAJ06597.1 - 0.21 11.4 0.6 0.45 10.3 0.4 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RRM_1 PF00076.17 OAJ06598.1 - 9.7e-57 188.5 0.1 4.9e-18 64.5 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06598.1 - 9.5e-45 150.4 0.0 4.6e-15 55.3 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06598.1 - 3.7e-22 77.9 0.0 2.9e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ06598.1 - 7.7e-07 28.9 0.0 0.33 10.8 0.0 3.4 3 0 0 3 3 3 3 RNA binding motif Limkain-b1 PF11608.3 OAJ06598.1 - 0.0018 17.9 0.1 5.3 6.8 0.0 4.0 3 3 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 OAJ06598.1 - 0.02 14.3 0.0 2.9 7.2 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp domain ArsA_ATPase PF02374.10 OAJ06599.1 - 1.9e-107 358.8 0.0 2.2e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 OAJ06599.1 - 1.8e-13 50.3 0.2 2.8e-13 49.7 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 OAJ06599.1 - 1.2e-07 31.7 0.0 3.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 OAJ06599.1 - 2.3e-05 23.7 0.1 9e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 OAJ06599.1 - 0.00056 19.3 0.5 0.0045 16.4 0.1 2.2 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 OAJ06599.1 - 0.0049 15.9 0.0 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin YhjQ PF06564.7 OAJ06599.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein AAA_16 PF13191.1 OAJ06599.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 OAJ06599.1 - 0.015 15.6 0.0 0.047 13.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain PhoH PF02562.11 OAJ06599.1 - 0.041 13.0 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 OAJ06599.1 - 0.075 12.6 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ06599.1 - 0.086 12.2 0.2 0.28 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 OAJ06599.1 - 0.086 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_17 PF13207.1 OAJ06599.1 - 0.094 13.5 0.0 0.21 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 OAJ06599.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 OAJ06599.1 - 0.16 11.4 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Nucleoplasmin PF03066.10 OAJ06600.1 - 0.88 9.0 6.3 1.5 8.2 3.8 1.7 2 0 0 2 2 2 0 Nucleoplasmin BAF1_ABF1 PF04684.8 OAJ06600.1 - 5.4 5.7 6.6 9.3 4.9 4.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Alba PF01918.16 OAJ06601.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Alba Collagen PF01391.13 OAJ06602.1 - 3.3e-57 189.9 452.7 2.3e-08 33.4 22.3 12.9 5 4 8 13 13 13 12 Collagen triple helix repeat (20 copies) Lactonase PF10282.4 OAJ06604.1 - 1.1e-68 231.8 0.0 1.3e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Peptidase_A4 PF01828.12 OAJ06604.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase A4 family Amidase_5 PF05382.8 OAJ06607.1 - 0.12 11.9 0.6 0.34 10.5 0.1 2.0 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase CAP PF00188.21 OAJ06609.1 - 6.1e-20 71.9 0.4 1.4e-19 70.7 0.3 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Endonuclease_NS PF01223.18 OAJ06610.1 - 4e-51 173.6 0.0 5.4e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Glyco_hydro_88 PF07470.8 OAJ06611.1 - 2e-11 43.5 0.2 2.5e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 NOT2_3_5 PF04153.13 OAJ06612.1 - 5.1e-36 123.5 2.5 8.4e-36 122.8 1.7 1.3 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family API5 PF05918.6 OAJ06612.1 - 1.9 6.8 5.3 2.3 6.5 3.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) BRO1 PF03097.13 OAJ06613.1 - 1.2e-101 340.2 0.0 2e-101 339.4 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 OAJ06613.1 - 1.2e-52 178.7 14.9 1.9e-52 178.1 10.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Peptidase_M50 PF02163.17 OAJ06614.1 - 8.1e-14 51.0 3.7 1.5e-12 46.9 2.2 2.7 2 1 0 2 2 2 1 Peptidase family M50 TF_Zn_Ribbon PF08271.7 OAJ06615.1 - 0.0038 16.4 1.3 0.0082 15.4 0.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.1 OAJ06615.1 - 0.61 9.3 3.6 0.27 10.5 0.7 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_47 PF01532.15 OAJ06617.1 - 1e-113 380.4 0.5 1.2e-113 380.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 OAJ06617.1 - 0.0065 15.9 1.7 2.3 7.5 0.2 3.2 3 0 0 3 3 3 2 Glycosyl hydrolase family 76 Zn_clus PF00172.13 OAJ06618.1 - 8.1e-08 32.0 10.9 1.4e-07 31.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 OAJ06619.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MFS_1 PF07690.11 OAJ06620.1 - 5.7e-42 143.6 20.5 7e-38 130.2 3.8 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06620.1 - 1.9e-10 39.9 1.7 1.9e-10 39.9 1.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 OAJ06620.1 - 0.00015 20.3 4.6 0.00015 20.3 3.2 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein C5-epim_C PF06662.8 OAJ06622.1 - 0.0051 16.1 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus 7TM-7TMR_HD PF07698.6 OAJ06622.1 - 0.2 11.1 13.0 0.024 14.1 3.2 2.6 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase zf-4CXXC_R1 PF10497.4 OAJ06623.1 - 2.9e-05 24.1 11.5 5.5e-05 23.2 8.0 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 UPF0139 PF03669.8 OAJ06624.1 - 0.048 13.1 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Hid1 PF12722.2 OAJ06625.1 - 4.4e-116 388.7 0.0 6.2e-101 338.5 0.0 3.6 2 2 0 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 OAJ06625.1 - 2.1e-43 148.4 0.0 5.3e-43 147.1 0.0 1.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SF-assemblin PF06705.6 OAJ06626.1 - 0.0027 16.8 1.9 0.0033 16.6 1.3 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.13 OAJ06626.1 - 0.0071 15.8 0.4 0.0089 15.5 0.3 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain 3HCDH_N PF02737.13 OAJ06626.1 - 0.017 14.8 2.3 0.022 14.3 1.5 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Filament PF00038.16 OAJ06626.1 - 0.053 12.9 0.8 0.066 12.6 0.5 1.0 1 0 0 1 1 1 0 Intermediate filament protein Herpes_UL25 PF01499.11 OAJ06626.1 - 0.36 9.0 4.1 0.43 8.8 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family WXG100 PF06013.7 OAJ06626.1 - 1.1 9.3 6.0 0.55 10.2 0.9 1.9 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DUF883 PF05957.8 OAJ06626.1 - 1.2 9.6 12.7 2.3 8.6 3.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MRFAP1 PF15155.1 OAJ06626.1 - 2.3 8.5 8.0 1.1 9.5 2.8 1.9 1 1 1 2 2 2 0 MORF4 family-associated protein1 Mpv17_PMP22 PF04117.7 OAJ06627.1 - 1.1e-24 85.8 0.6 1.6e-24 85.2 0.4 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Peptidase_S8 PF00082.17 OAJ06628.1 - 1.4e-45 155.6 0.3 8.6e-45 153.0 0.2 2.2 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ06628.1 - 5e-10 39.7 6.6 8.7e-10 38.9 1.7 2.6 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ06628.1 - 1.7e-09 37.2 0.0 4.6e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 OAJ06628.1 - 0.051 14.1 0.2 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 Helicase_RecD PF05127.9 OAJ06629.1 - 3.6e-52 176.5 0.0 6.1e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 OAJ06629.1 - 1.7e-32 110.9 0.0 3.3e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) GNAT_acetyltr_2 PF13718.1 OAJ06629.1 - 3.6e-12 46.0 0.0 5.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 NIF PF03031.13 OAJ06630.1 - 1.3e-07 31.3 0.0 0.0024 17.5 0.0 3.1 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Methyltransf_28 PF02636.12 OAJ06631.1 - 6.2e-65 219.0 0.0 8e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SGS PF05002.10 OAJ06632.1 - 1.9e-25 88.4 1.2 3.4e-25 87.6 0.8 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 OAJ06632.1 - 3.4e-10 40.3 0.0 9.1e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 CS domain Uds1 PF15456.1 OAJ06633.1 - 1.8e-16 60.2 1.3 9.1e-13 48.2 0.2 14.4 5 2 6 13 13 13 3 Up-regulated During Septation DUF1469 PF07332.6 OAJ06634.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Peptidase_S8 PF00082.17 OAJ06635.1 - 4.6e-42 144.1 4.7 7.8e-42 143.3 3.3 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 OAJ06635.1 - 6.7e-09 36.1 0.5 1.5e-08 35.0 0.4 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 OAJ06635.1 - 6.8e-05 22.5 0.0 0.00018 21.1 0.0 1.8 1 0 0 1 1 1 1 PA domain Pkinase PF00069.20 OAJ06636.1 - 1.5e-70 237.3 0.0 1.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06636.1 - 6e-31 107.4 0.0 8.2e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 OAJ06636.1 - 4.2e-13 49.5 0.9 1.7e-12 47.6 0.6 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ06636.1 - 6.2e-05 22.0 0.0 0.00016 20.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ06636.1 - 0.027 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 OAJ06636.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactonase PF10282.4 OAJ06639.1 - 2.4e-65 220.9 0.0 2.8e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Npa1 PF11707.3 OAJ06641.1 - 9.8e-66 221.9 0.0 3.1e-42 144.7 0.0 3.4 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal Na_Ca_ex PF01699.19 OAJ06642.1 - 1.5e-40 138.0 29.4 2e-23 82.5 7.0 3.3 3 1 1 4 4 4 2 Sodium/calcium exchanger protein MSP1_C PF07462.6 OAJ06642.1 - 8.7 4.6 3.7 24 3.1 2.6 1.7 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Complex1_49kDa PF00346.14 OAJ06643.1 - 3.3e-127 423.1 0.0 4.4e-127 422.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 OAJ06643.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase FAD_binding_8 PF08022.7 OAJ06648.1 - 2.4e-19 69.1 0.0 4.5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ06648.1 - 6.6e-14 52.0 0.0 1.9e-12 47.3 0.0 2.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ06648.1 - 7.6e-10 38.9 7.4 1.3e-09 38.2 4.6 1.8 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ06648.1 - 0.00038 20.5 0.0 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.7 OAJ06649.1 - 7.1e-18 64.4 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ06649.1 - 9.7e-15 54.8 0.0 1.7e-11 44.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ06649.1 - 2.1e-10 40.7 9.8 2.1e-10 40.7 6.8 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ06649.1 - 0.00046 20.2 0.0 0.0015 18.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_8 PF08022.7 OAJ06650.1 - 1.8e-19 69.5 0.0 3.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ06650.1 - 8.5e-16 58.2 0.0 9.1e-15 54.8 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 OAJ06650.1 - 1.4e-09 38.0 5.1 1.4e-09 38.0 3.6 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 OAJ06650.1 - 0.00096 19.2 0.0 0.0033 17.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain HAD_2 PF13419.1 OAJ06652.1 - 2.4e-14 53.9 0.0 7e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ06652.1 - 7e-07 29.8 0.0 2.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ06652.1 - 0.0018 17.9 0.0 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ABC2_membrane PF01061.19 OAJ06653.1 - 1.2e-29 102.9 14.5 2e-29 102.2 10.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ06653.1 - 1.2e-26 93.5 0.6 2e-26 92.9 0.1 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ06653.1 - 8.8e-08 32.4 0.1 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ06653.1 - 0.00011 21.6 0.1 0.093 12.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ06653.1 - 0.00011 21.6 0.7 0.00095 18.6 0.3 2.5 2 1 1 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 OAJ06653.1 - 0.00015 21.9 0.3 0.0016 18.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ06653.1 - 0.00016 21.7 0.2 0.00046 20.2 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ06653.1 - 0.00072 18.7 0.3 0.0015 17.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 OAJ06653.1 - 0.0011 18.0 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 OAJ06653.1 - 0.0029 17.3 0.4 0.031 14.0 0.2 2.6 1 1 0 1 1 1 1 Part of AAA domain AAA_23 PF13476.1 OAJ06653.1 - 0.017 15.4 0.1 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 OAJ06653.1 - 0.043 12.7 0.3 0.098 11.5 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 OAJ06653.1 - 0.091 12.6 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 OAJ06653.1 - 0.098 12.0 0.3 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 OAJ06653.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 OAJ06653.1 - 0.13 12.7 0.3 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 OAJ06653.1 - 0.36 10.7 1.3 0.41 10.5 0.1 1.7 2 0 0 2 2 1 0 AAA domain UPF1_Zn_bind PF09416.5 OAJ06654.1 - 2.2e-73 244.8 9.0 6.2e-73 243.4 5.5 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 OAJ06654.1 - 9.7e-59 198.1 0.0 2.5e-58 196.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ06654.1 - 7.6e-56 189.3 1.4 1.1e-55 188.7 1.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ06654.1 - 1.1e-12 47.4 0.2 4.7e-12 45.4 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 OAJ06654.1 - 2.4e-11 43.6 0.0 2.8e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 OAJ06654.1 - 1.7e-07 31.2 0.0 4.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 OAJ06654.1 - 3.2e-05 23.5 1.7 0.24 10.8 0.0 3.7 3 1 2 5 5 5 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 OAJ06654.1 - 5.8e-05 22.2 0.4 0.00069 18.6 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 OAJ06654.1 - 0.0002 21.0 0.2 0.00096 18.8 0.1 2.1 1 1 0 1 1 1 1 Helicase SRP54 PF00448.17 OAJ06654.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 OAJ06654.1 - 0.018 14.0 0.1 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.2 OAJ06654.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 OAJ06654.1 - 0.051 13.7 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 OAJ06654.1 - 0.051 12.6 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 KaiC DEAD PF00270.24 OAJ06654.1 - 0.06 12.8 0.3 0.15 11.5 0.2 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA PF00004.24 OAJ06654.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 OAJ06654.1 - 0.11 11.2 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 OAJ06654.1 - 0.12 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 OAJ06654.1 - 0.12 11.5 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Ribonuclease PF00545.15 OAJ06655.1 - 4.2e-16 58.7 1.1 5.4e-16 58.4 0.8 1.2 1 0 0 1 1 1 1 ribonuclease Annexin PF00191.15 OAJ06656.1 - 7.3e-51 169.9 0.2 2.5e-13 49.7 0.0 4.2 4 0 0 4 4 4 4 Annexin VTC PF09359.5 OAJ06657.1 - 2.3e-100 335.2 0.0 8.4e-100 333.4 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 OAJ06657.1 - 4e-29 102.2 4.1 4e-29 102.2 2.9 3.3 2 2 0 2 2 2 1 SPX domain DUF202 PF02656.10 OAJ06657.1 - 1.8e-12 47.2 2.6 2.4e-12 46.8 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ribosomal_60s PF00428.14 OAJ06657.1 - 0.12 12.8 5.1 0.77 10.1 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1154 PF06631.6 OAJ06657.1 - 0.13 11.9 3.4 7.1 6.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) DUF1908 PF08926.6 OAJ06658.1 - 0.25 10.0 4.2 0.44 9.2 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) PQ-loop PF04193.9 OAJ06659.1 - 1.1e-12 47.2 0.4 1.1e-12 47.2 0.3 2.2 2 0 0 2 2 2 1 PQ loop repeat DUF21 PF01595.15 OAJ06659.1 - 0.00084 18.6 0.1 0.00084 18.6 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function DUF21 BSP_II PF05432.6 OAJ06659.1 - 0.0038 16.5 2.2 0.0051 16.1 1.5 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 OAJ06659.1 - 0.056 12.9 2.2 0.079 12.4 1.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Bindin PF02084.10 OAJ06659.1 - 0.058 13.4 1.8 0.11 12.5 1.2 1.3 1 0 0 1 1 1 0 Bindin Nop14 PF04147.7 OAJ06659.1 - 2.8 5.7 5.3 5.2 4.8 3.7 1.3 1 0 0 1 1 1 0 Nop14-like family NIF PF03031.13 OAJ06660.1 - 2.4e-20 72.7 0.0 6.7e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 OAJ06660.1 - 4.2e-09 36.1 0.0 7.7e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 OAJ06660.1 - 9.4e-07 28.8 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TFIIA PF03153.8 OAJ06660.1 - 0.003 17.5 5.7 0.003 17.5 4.0 4.3 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.15 OAJ06661.1 - 7.5e-79 264.9 0.4 7.5e-79 264.9 0.3 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 OAJ06661.1 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 OAJ06661.1 - 0.026 13.7 0.4 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PcfJ PF14284.1 OAJ06661.1 - 0.81 9.1 5.9 13 5.2 1.5 2.5 2 1 0 2 2 2 0 PcfJ-like protein SNF2_N PF00176.18 OAJ06662.1 - 7.1e-67 225.3 0.0 1e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 OAJ06662.1 - 1.6e-20 73.0 0.0 3.3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 OAJ06662.1 - 4.3e-15 55.3 0.0 9.9e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ06662.1 - 3.4e-05 23.7 0.0 0.00042 20.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 OAJ06662.1 - 0.00015 21.2 0.0 0.00044 19.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 OAJ06662.1 - 0.00051 19.6 11.3 0.001 18.7 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ06662.1 - 0.0013 18.7 16.1 0.0024 17.8 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ06662.1 - 0.0024 17.4 15.3 0.0046 16.5 10.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ06662.1 - 0.0073 16.1 13.3 0.014 15.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ06662.1 - 0.029 14.1 14.8 0.052 13.2 10.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.10 OAJ06662.1 - 0.052 12.9 0.1 0.17 11.2 0.0 1.7 1 1 0 1 1 1 0 DEAD_2 Ribosomal_L22e PF01776.12 OAJ06663.1 - 1e-45 154.3 0.1 1.2e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Big_3 PF07523.7 OAJ06663.1 - 0.16 12.0 0.6 4.5 7.4 0.1 2.4 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Acetyltransf_1 PF00583.19 OAJ06664.1 - 4.9e-09 36.0 0.0 1.7e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 OAJ06664.1 - 0.00042 20.4 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 OAJ06664.1 - 0.0012 18.7 0.0 0.009 15.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 OAJ06664.1 - 0.12 12.2 0.5 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 OAJ06664.1 - 0.13 12.4 0.1 0.46 10.6 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP2 PF01569.16 OAJ06665.1 - 2e-12 46.9 2.5 3.8e-12 46.0 1.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 OAJ06665.1 - 0.024 14.3 0.1 0.024 14.3 0.1 2.7 3 1 1 4 4 4 0 Divergent PAP2 family DUF2517 PF10725.4 OAJ06665.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) DPBB_1 PF03330.13 OAJ06666.1 - 0.00025 20.9 0.2 0.0012 18.8 0.2 2.2 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 OAJ06667.1 - 1.8e-62 210.8 0.0 9.3e-34 116.7 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06667.1 - 2.4e-30 105.4 0.0 5e-15 55.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 OAJ06667.1 - 4e-17 62.1 0.0 1.2e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.2 OAJ06667.1 - 1.2e-13 50.8 0.0 1.2e-13 50.8 0.0 3.0 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.1 OAJ06667.1 - 4.9e-13 48.8 1.9 1e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 OAJ06667.1 - 2.2e-05 24.3 0.1 2.2e-05 24.3 0.1 3.9 3 2 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 OAJ06667.1 - 5.6e-05 22.2 0.0 0.00052 19.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like UQ_con PF00179.21 OAJ06667.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Methyltransf_16 PF10294.4 OAJ06668.1 - 2.2e-16 59.8 0.0 1.2e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 OAJ06668.1 - 0.00021 21.8 0.0 0.00046 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ06668.1 - 0.0078 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ06668.1 - 0.023 14.7 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 OAJ06668.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 OAJ06668.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 OAJ06670.1 - 4.7e-15 55.4 0.0 6.3e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.13 OAJ06671.1 - 4e-10 39.4 8.9 6.9e-10 38.6 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Caldesmon PF02029.10 OAJ06671.1 - 0.069 11.5 0.1 0.099 11.0 0.1 1.2 1 0 0 1 1 1 0 Caldesmon tRNA_bind PF01588.15 OAJ06673.1 - 2.8e-27 94.3 0.0 4.9e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.20 OAJ06673.1 - 0.0084 16.0 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ06673.1 - 0.0085 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 OAJ06674.1 - 0.49 9.4 2.7 0.7 8.9 1.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain BTV_NS2 PF04514.7 OAJ06674.1 - 1.7 7.4 11.2 2.3 6.9 7.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP_sp32 PF07222.7 OAJ06674.1 - 2.8 7.0 9.5 4.7 6.3 6.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 ABC_tran PF00005.22 OAJ06675.1 - 3.6e-37 127.7 1.2 4.9e-20 72.2 0.0 4.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 OAJ06675.1 - 3.8e-10 40.2 0.2 6.4e-05 23.0 0.0 4.3 4 0 0 4 4 4 1 AAA domain SMC_N PF02463.14 OAJ06675.1 - 9.8e-08 31.4 0.2 0.17 11.0 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 OAJ06675.1 - 1.3e-06 28.1 3.7 1.3e-06 28.1 2.6 2.7 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 OAJ06675.1 - 9e-06 25.1 0.1 0.021 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 OAJ06675.1 - 2.3e-05 24.2 0.2 0.0029 17.5 0.0 3.2 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 OAJ06675.1 - 0.00099 18.3 0.2 0.02 14.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 OAJ06675.1 - 0.0043 17.0 0.0 0.58 10.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 OAJ06675.1 - 0.014 14.8 1.4 2.8 7.2 0.0 3.6 4 0 0 4 4 4 0 AAA-like domain NACHT PF05729.7 OAJ06675.1 - 0.015 14.9 0.2 5.2 6.6 0.0 2.8 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 OAJ06675.1 - 0.017 15.3 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 OAJ06675.1 - 0.038 14.1 0.1 2.8 8.1 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 OAJ06675.1 - 0.057 13.7 8.6 1.4 9.1 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 OAJ06675.1 - 0.28 11.9 3.2 8.7 7.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.12 OAJ06675.1 - 3.1 7.5 7.9 5.9 6.6 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_16 PF13191.1 OAJ06675.1 - 9.1 6.2 12.3 0.23 11.4 0.2 3.7 3 3 0 3 3 3 0 AAA ATPase domain adh_short PF00106.20 OAJ06676.1 - 1.8e-25 89.7 1.1 4.4e-25 88.5 0.8 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ06676.1 - 2.1e-11 43.8 0.3 3.4e-11 43.1 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ06676.1 - 1.3e-09 38.1 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 OAJ06676.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_N PF08240.7 OAJ06677.1 - 3.8e-07 29.8 0.0 8.8e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ06677.1 - 7.9e-06 25.4 0.0 1.8e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ06677.1 - 0.035 14.9 0.0 0.076 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELYS PF13934.1 OAJ06678.1 - 4.8e-07 29.7 0.0 9.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore complex assembly PHY PF00360.15 OAJ06679.1 - 1.6e-24 86.0 0.0 3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 OAJ06679.1 - 9.9e-20 70.3 0.4 2.4e-19 69.1 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 OAJ06679.1 - 2.9e-15 56.7 0.0 7e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain Response_reg PF00072.19 OAJ06679.1 - 2.4e-14 53.2 0.2 1.5e-13 50.7 0.2 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 OAJ06679.1 - 1.5e-12 47.3 0.4 3.9e-12 45.9 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 OAJ06679.1 - 1.7e-10 41.3 0.0 4.8e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold Aa_trans PF01490.13 OAJ06680.1 - 1.1e-05 24.0 0.0 0.0044 15.5 0.0 2.4 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein PAT1 PF09770.4 OAJ06681.1 - 1.8e-158 529.2 62.2 1.7e-134 449.9 8.6 3.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Draxin PF15550.1 OAJ06681.1 - 5.8 6.4 14.3 0.37 10.4 3.8 2.7 3 0 0 3 3 3 0 Draxin RR_TM4-6 PF06459.7 OAJ06681.1 - 6.8 6.5 12.3 0.12 12.3 3.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 OAJ06681.1 - 8.1 5.7 15.3 20 4.4 10.6 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tim54 PF11711.3 OAJ06681.1 - 9 4.7 13.2 0.71 8.3 5.6 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 STAG PF08514.6 OAJ06686.1 - 5.2e-30 103.5 0.6 1.7e-29 101.9 0.2 2.1 2 0 0 2 2 2 1 STAG domain Acyl-CoA_dh_2 PF08028.6 OAJ06687.1 - 8.1e-14 52.0 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ06687.1 - 4.2e-06 27.3 0.1 8.9e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ06687.1 - 0.0036 17.4 0.6 0.018 15.1 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Lipase_3 PF01764.20 OAJ06688.1 - 3.3e-12 46.1 0.0 2.2e-11 43.5 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) YjeF_N PF03853.10 OAJ06689.1 - 1.6e-35 122.2 0.0 2.2e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S6e PF01092.14 OAJ06690.1 - 6.1e-57 190.7 0.2 6.1e-57 190.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Biotin_carb_C PF02785.14 OAJ06690.1 - 0.061 13.3 0.3 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Biotin carboxylase C-terminal domain Ribosomal_S13_N PF08069.7 OAJ06691.1 - 6.1e-30 102.8 0.3 1e-29 102.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 OAJ06691.1 - 6.3e-21 73.9 0.1 8.4e-21 73.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 OAJ06691.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain NIR_SIR PF01077.17 OAJ06692.1 - 4.5e-29 100.8 0.0 9.3e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 OAJ06692.1 - 1.4e-21 77.2 0.0 3e-21 76.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 OAJ06692.1 - 1.6e-15 56.7 0.0 6.9e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 OAJ06692.1 - 8.3e-14 51.7 0.5 8.3e-14 51.7 0.3 3.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 OAJ06692.1 - 1.4e-13 50.6 4.2 2.5e-12 46.6 2.8 2.5 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 OAJ06692.1 - 1.3e-10 40.6 0.0 2.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 OAJ06692.1 - 1.6e-10 40.3 0.3 6.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 OAJ06692.1 - 6.5e-07 29.6 1.2 0.00011 22.3 0.0 3.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 OAJ06692.1 - 0.00019 21.2 3.3 1.2 8.8 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.13 OAJ06692.1 - 0.0078 16.1 2.7 1.8 8.6 0.0 3.6 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.1 OAJ06692.1 - 0.0081 16.1 0.4 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ06692.1 - 0.0086 15.0 7.8 0.077 11.8 0.1 3.7 4 1 1 5 5 5 1 FAD dependent oxidoreductase GIDA PF01134.17 OAJ06692.1 - 0.0091 14.8 0.1 3.2 6.4 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 OAJ06692.1 - 0.023 13.5 0.3 1.5 7.5 0.1 2.7 1 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 OAJ06692.1 - 0.057 12.3 0.1 1.4 7.7 0.0 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 OAJ06692.1 - 0.099 12.9 1.5 15 5.9 0.1 2.9 3 0 0 3 3 2 0 Putative NAD(P)-binding ThiF PF00899.16 OAJ06692.1 - 0.23 11.2 2.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 ThiF family DUF2583 PF10762.4 OAJ06693.1 - 0.095 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) DUF1469 PF07332.6 OAJ06693.1 - 0.15 11.7 1.1 0.2 11.3 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4190 PF13828.1 OAJ06693.1 - 1.9 8.0 4.9 0.46 10.0 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Malate_synthase PF01274.17 OAJ06695.1 - 2.2e-204 679.3 0.0 2.5e-204 679.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase BRAP2 PF07576.7 OAJ06696.1 - 6.6e-20 70.7 0.0 1.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 OAJ06696.1 - 1.2e-17 63.8 3.5 1.2e-17 63.8 2.4 1.8 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 OAJ06696.1 - 1.1e-08 34.7 10.6 1.1e-08 34.7 7.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 OAJ06696.1 - 2.5e-05 24.3 6.1 2.5e-05 24.3 4.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ06696.1 - 2.7e-05 23.7 9.4 2.7e-05 23.7 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ06696.1 - 5.8e-05 22.7 8.3 5.8e-05 22.7 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 OAJ06696.1 - 0.00052 19.8 4.2 0.0013 18.5 2.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 OAJ06696.1 - 0.00057 19.5 5.4 0.0045 16.6 1.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 OAJ06696.1 - 0.00061 19.7 10.1 0.00061 19.7 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 OAJ06696.1 - 0.00091 18.8 8.0 0.00091 18.8 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 OAJ06696.1 - 0.004 17.1 0.2 0.013 15.4 0.0 1.9 2 0 0 2 2 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 OAJ06696.1 - 0.051 13.1 6.9 0.11 12.1 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FlaC_arch PF05377.6 OAJ06696.1 - 2.6 8.0 6.1 0.38 10.6 0.2 2.4 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) zf-RING_6 PF14835.1 OAJ06696.1 - 4.8 7.0 11.8 0.037 13.7 1.9 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Y_phosphatase PF00102.22 OAJ06697.1 - 8.3e-31 107.1 0.0 2.2e-15 56.6 0.0 2.9 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ06697.1 - 9.2e-06 25.2 0.1 3.7e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain TAF4 PF05236.9 OAJ06698.1 - 7.2e-21 74.6 11.7 3.8e-17 62.4 0.0 4.0 4 0 0 4 4 4 3 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.27 OAJ06699.1 - 5e-28 95.9 4.1 4.7e-10 38.9 0.0 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 OAJ06699.1 - 0.0042 17.3 1.5 0.0042 17.3 1.0 4.8 3 2 1 4 4 4 1 Centromere protein B dimerisation domain Cytochrom_D1 PF02239.11 OAJ06699.1 - 0.018 13.3 0.0 0.063 11.5 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain SET PF00856.23 OAJ06699.1 - 0.041 14.1 3.7 0.064 13.5 0.0 2.8 3 0 0 3 3 3 0 SET domain FA_hydroxylase PF04116.8 OAJ06700.1 - 2e-14 53.9 16.1 2e-14 53.9 11.1 2.0 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Lactamase_B PF00753.22 OAJ06701.1 - 1.8e-11 44.0 4.4 1.4e-10 41.1 3.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 OAJ06701.1 - 0.0068 15.9 0.2 0.012 15.1 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain HORMA PF02301.13 OAJ06702.1 - 2.9e-32 111.8 0.0 5.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 OAJ06702.1 - 1.8e-07 30.7 1.5 3.5e-07 29.8 1.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 OAJ06702.1 - 0.0015 17.7 3.7 0.0027 16.9 2.5 1.4 1 0 0 1 1 1 1 PHD-finger SAPS PF04499.10 OAJ06703.1 - 4.2e-145 484.0 0.0 1.5e-144 482.2 0.0 1.9 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.14 OAJ06703.1 - 0.093 10.5 0.4 0.14 10.0 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn60_TCP1 PF00118.19 OAJ06713.1 - 5.2e-136 454.0 5.9 6.1e-136 453.8 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glycogen_syn PF05693.8 OAJ06713.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase SLX9 PF15341.1 OAJ06714.1 - 1.3e-18 67.5 6.0 1.3e-18 67.5 4.1 1.6 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Taxilin PF09728.4 OAJ06714.1 - 0.057 12.4 0.3 0.08 12.0 0.2 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ERM PF00769.14 OAJ06714.1 - 0.51 9.8 5.6 0.73 9.3 3.9 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SOBP PF15279.1 OAJ06714.1 - 1.6 9.0 5.0 1.9 8.8 3.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1399 PF07173.7 OAJ06715.1 - 6.5e-15 55.6 4.0 5.6e-13 49.3 0.1 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1399) DUF1399 PF07173.7 OAJ06716.1 - 9.3e-16 58.3 3.8 4.5e-14 52.8 0.1 3.5 3 1 1 4 4 4 2 Protein of unknown function (DUF1399) Colipase-like PF15083.1 OAJ06717.1 - 0.031 14.1 0.3 0.031 14.1 0.2 10.1 4 3 3 8 8 8 0 Colipase-like Prp31_C PF09785.4 OAJ06718.1 - 8.8e-39 132.7 7.5 2.1e-38 131.5 5.2 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 OAJ06718.1 - 4.2e-36 123.5 0.2 7.5e-36 122.6 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ06718.1 - 3.8e-20 71.4 0.0 8.8e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOA36 PF06524.7 OAJ06718.1 - 1.9 7.6 13.6 3.4 6.8 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein Colipase-like PF15083.1 OAJ06720.1 - 0.77 9.7 19.0 0.25 11.2 3.6 3.3 2 1 0 2 2 2 0 Colipase-like DUF3437 PF11919.3 OAJ06722.1 - 4.4e-28 96.8 0.1 3.7e-27 93.8 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 OAJ06722.1 - 0.0014 18.5 0.1 0.073 13.1 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 OAJ06722.1 - 0.0055 16.9 0.0 0.066 13.4 0.0 3.0 2 1 0 2 2 2 1 HEAT repeats AAA_29 PF13555.1 OAJ06722.1 - 0.0087 15.5 0.9 0.024 14.1 0.6 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1546 PF07571.8 OAJ06722.1 - 0.09 12.8 0.1 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Striatin PF08232.7 OAJ06724.1 - 0.14 12.4 4.7 0.64 10.3 3.2 2.1 1 0 0 1 1 1 0 Striatin family G10 PF01125.12 OAJ06725.1 - 3.6e-63 211.4 5.4 4.1e-63 211.2 3.8 1.0 1 0 0 1 1 1 1 G10 protein HAD_2 PF13419.1 OAJ06725.1 - 0.06 13.5 0.1 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DNA_RNApol_7kD PF03604.8 OAJ06725.1 - 0.77 9.2 9.1 0.21 11.0 3.1 2.2 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Syntaxin-6_N PF09177.6 OAJ06726.1 - 1.4e-18 67.0 1.9 1.2e-17 64.0 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 OAJ06726.1 - 6.1e-09 35.4 3.5 6.1e-09 35.4 2.4 2.9 3 0 0 3 3 3 1 SNARE domain Use1 PF09753.4 OAJ06726.1 - 1.9e-05 24.2 0.1 0.0002 20.8 0.0 2.0 1 1 1 2 2 2 1 Membrane fusion protein Use1 HisKA_3 PF07730.8 OAJ06726.1 - 0.001 19.3 5.8 0.14 12.5 0.2 2.5 2 0 0 2 2 2 2 Histidine kinase FliJ PF02050.11 OAJ06726.1 - 0.0011 18.9 7.6 0.03 14.3 2.7 2.5 2 1 0 2 2 2 1 Flagellar FliJ protein FliD_C PF07195.7 OAJ06726.1 - 0.0065 15.7 2.8 1.5 8.0 0.5 2.1 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus Sec34 PF04136.10 OAJ06726.1 - 0.0095 15.6 0.1 0.2 11.3 0.1 2.1 2 0 0 2 2 2 1 Sec34-like family GP41 PF00517.12 OAJ06726.1 - 0.021 14.3 3.7 0.39 10.2 0.1 2.7 2 1 1 3 3 3 0 Retroviral envelope protein DUF883 PF05957.8 OAJ06726.1 - 0.027 14.8 0.3 0.027 14.8 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF2959 PF11172.3 OAJ06726.1 - 0.053 13.2 1.4 0.87 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DUF848 PF05852.6 OAJ06726.1 - 0.17 11.7 6.3 0.43 10.4 1.3 2.3 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Snapin_Pallidin PF14712.1 OAJ06726.1 - 0.18 12.1 3.1 1.1 9.6 0.8 2.3 2 0 0 2 2 2 0 Snapin/Pallidin DUF4407 PF14362.1 OAJ06726.1 - 0.19 10.6 2.8 0.45 9.4 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IFT57 PF10498.4 OAJ06726.1 - 0.19 10.4 1.7 3.7 6.2 0.8 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4164 PF13747.1 OAJ06726.1 - 0.25 11.5 4.0 3 8.0 0.1 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) FliD_N PF02465.13 OAJ06726.1 - 0.33 11.3 3.2 3.4 8.0 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Baculo_PEP_C PF04513.7 OAJ06726.1 - 0.39 10.5 3.4 5.6 6.7 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PEP-utilisers_N PF05524.8 OAJ06726.1 - 0.47 10.2 5.8 1.1 9.0 0.2 2.7 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal ApoLp-III PF07464.6 OAJ06726.1 - 0.54 10.2 3.4 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.6 OAJ06726.1 - 0.65 8.5 3.3 4.2 5.9 1.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HisKA PF00512.20 OAJ06726.1 - 8 6.5 9.0 8.3 6.4 0.1 3.1 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain CENP-F_leu_zip PF10473.4 OAJ06726.1 - 8.8 6.1 10.6 17 5.2 0.3 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cyclin PF08613.6 OAJ06727.1 - 2.8e-13 50.5 0.2 1.8e-10 41.3 0.0 2.8 3 0 0 3 3 3 2 Cyclin Ras PF00071.17 OAJ06728.1 - 5.7e-62 207.8 0.1 6.6e-62 207.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ06728.1 - 5.6e-20 72.0 0.0 7.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ06728.1 - 2e-12 46.7 0.0 2.7e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 OAJ06728.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ06728.1 - 2e-05 24.1 0.1 7.9e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 OAJ06728.1 - 9.1e-05 22.6 0.0 0.00032 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 OAJ06728.1 - 0.0021 17.2 0.1 0.005 16.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 OAJ06728.1 - 0.0052 16.0 0.0 0.0092 15.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 OAJ06728.1 - 0.014 15.3 0.6 0.042 13.8 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 OAJ06728.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 OAJ06728.1 - 0.032 13.7 0.0 0.083 12.3 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 OAJ06728.1 - 0.035 13.2 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 OAJ06728.1 - 0.036 14.3 0.1 0.078 13.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 OAJ06728.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 OAJ06728.1 - 0.069 12.8 0.1 0.18 11.5 0.0 1.7 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 OAJ06728.1 - 0.098 12.6 0.1 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain CoA_binding PF02629.14 OAJ06729.1 - 4.7e-29 100.7 3.7 4.5e-28 97.5 0.1 2.7 2 1 1 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 OAJ06729.1 - 7.6e-20 71.0 0.5 1.2e-19 70.3 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 OAJ06729.1 - 3.2e-09 36.5 0.1 8.1e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 OAJ06729.1 - 3.5e-05 23.9 0.1 0.00022 21.3 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 OAJ06729.1 - 0.0015 19.0 0.0 0.0043 17.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF3844 PF12955.2 OAJ06730.1 - 2.6e-26 91.7 0.1 4.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Prefoldin_2 PF01920.15 OAJ06731.1 - 1.8e-21 75.8 1.5 2.2e-21 75.6 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 OAJ06731.1 - 1.2e-05 24.7 3.2 0.0064 15.9 0.0 2.2 1 1 1 2 2 2 2 Septum formation initiator FTA4 PF13093.1 OAJ06731.1 - 0.005 16.2 0.4 0.0063 15.9 0.3 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2968 PF11180.3 OAJ06731.1 - 0.0055 16.0 0.6 0.37 10.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Spc24 PF08286.6 OAJ06731.1 - 0.0075 15.9 5.6 0.9 9.2 1.7 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 ADIP PF11559.3 OAJ06731.1 - 0.01 15.7 3.1 0.79 9.6 0.1 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NIT PF08376.5 OAJ06731.1 - 0.029 13.8 0.7 0.052 13.0 0.1 1.6 2 0 0 2 2 2 0 Nitrate and nitrite sensing STAT_alpha PF01017.15 OAJ06731.1 - 0.053 13.2 0.1 0.11 12.2 0.1 1.6 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF4164 PF13747.1 OAJ06731.1 - 0.06 13.4 8.0 0.44 10.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FlaC_arch PF05377.6 OAJ06731.1 - 0.074 12.9 0.5 6.8 6.6 0.0 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 OAJ06731.1 - 0.086 12.5 0.6 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF4208 PF13907.1 OAJ06731.1 - 0.11 12.7 0.6 0.28 11.4 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) TBPIP PF07106.8 OAJ06731.1 - 0.12 11.9 1.7 0.55 9.7 0.1 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MutS_IV PF05190.13 OAJ06731.1 - 0.12 12.5 1.9 0.37 10.9 0.1 2.2 2 1 0 2 2 2 0 MutS family domain IV HalX PF08663.5 OAJ06731.1 - 0.19 11.7 4.3 0.14 12.1 0.5 2.2 2 0 0 2 2 2 0 HalX domain TMF_DNA_bd PF12329.3 OAJ06731.1 - 0.27 11.0 2.0 5.7 6.8 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 OAJ06731.1 - 0.37 10.5 3.8 6.4 6.5 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 OAJ06731.1 - 0.59 9.5 6.6 3 7.2 1.7 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 Wbp11 PF09429.5 OAJ06731.1 - 0.99 9.4 3.4 0.89 9.5 0.1 2.2 2 1 0 2 2 2 0 WW domain binding protein 11 IncA PF04156.9 OAJ06731.1 - 1.7 8.1 5.4 6.3 6.3 3.8 1.7 1 1 0 1 1 1 0 IncA protein DUF2489 PF10675.4 OAJ06732.1 - 0.06 13.0 6.5 0.087 12.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF4407 PF14362.1 OAJ06732.1 - 1.6 7.6 9.5 2.4 7.0 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_III_AF PF09581.5 OAJ06732.1 - 4.5 7.0 5.8 7.1 6.4 4.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF3437 PF11919.3 OAJ06734.1 - 7.9e-20 70.3 2.1 1.3e-18 66.5 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 OAJ06734.1 - 4e-05 23.8 1.9 0.67 10.2 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 OAJ06734.1 - 0.00066 20.0 0.2 1.5 9.4 0.0 4.2 3 0 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 OAJ06734.1 - 0.0052 16.7 2.9 6.4 7.1 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat PolyA_pol PF01743.15 OAJ06735.1 - 5.2e-23 81.6 0.0 8.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 OAJ06735.1 - 0.0005 19.5 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A COesterase PF00135.23 OAJ06736.1 - 3e-101 339.7 0.0 4.2e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ06736.1 - 2.6e-11 43.4 0.6 1.3e-10 41.2 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ06736.1 - 0.043 13.5 0.2 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ06736.1 - 0.13 11.4 0.7 0.2 10.8 0.5 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family HAD_2 PF13419.1 OAJ06737.1 - 7.6e-23 81.6 0.3 1.3e-22 80.8 0.2 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 OAJ06737.1 - 1.1e-14 53.6 0.1 4.6e-06 26.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.28 OAJ06737.1 - 1.4e-05 24.6 0.1 3.6e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ06737.1 - 0.00011 21.9 0.1 0.00024 20.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like HSBP1 PF06825.7 OAJ06738.1 - 1.7e-10 40.3 0.1 2.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 adh_short PF00106.20 OAJ06739.1 - 1.5e-29 103.0 1.0 1.5e-29 103.0 0.7 1.7 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ06739.1 - 1.7e-28 100.0 0.2 2e-28 99.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ06739.1 - 1e-12 48.1 3.4 1.4e-12 47.6 0.8 2.2 1 1 1 2 2 2 1 KR domain Exo_endo_phos PF03372.18 OAJ06740.1 - 1.2e-21 77.8 2.3 4e-11 43.3 0.3 3.0 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Sec7 PF01369.15 OAJ06741.1 - 1.1e-61 207.7 0.0 2.2e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 OAJ06741.1 - 1.3e-06 28.0 0.8 0.52 9.7 0.0 4.2 3 0 0 3 3 3 3 Guanine nucleotide exchange factor in Golgi transport N-terminal GWT1 PF06423.7 OAJ06742.1 - 4.6e-32 110.9 0.0 3.1e-21 75.8 0.0 3.1 3 0 0 3 3 3 2 GWT1 SR-25 PF10500.4 OAJ06742.1 - 0.0046 16.4 6.6 0.0046 16.4 4.6 4.3 4 0 0 4 4 4 2 Nuclear RNA-splicing-associated protein DUF4228 PF14009.1 OAJ06742.1 - 1.8 8.6 9.8 0.2 11.8 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) FimP PF09766.4 OAJ06743.1 - 0.97 8.4 19.0 2.1 7.3 13.2 1.5 1 0 0 1 1 1 0 Fms-interacting protein Nuc-transf PF10127.4 OAJ06746.1 - 0.049 12.9 0.3 0.071 12.4 0.2 1.1 1 0 0 1 1 1 0 Predicted nucleotidyltransferase Transposase_21 PF02992.9 OAJ06747.1 - 9.1e-16 57.6 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Miro PF08477.8 OAJ06748.1 - 2.6e-26 92.4 0.0 6.6e-12 45.9 0.0 4.3 4 0 0 4 4 4 3 Miro-like protein EF_assoc_2 PF08356.7 OAJ06748.1 - 2.5e-24 84.8 0.0 9e-24 83.0 0.0 1.9 3 0 0 3 3 1 1 EF hand associated EF_assoc_1 PF08355.7 OAJ06748.1 - 2.5e-21 74.7 0.0 1.1e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 OAJ06748.1 - 1.5e-15 56.9 0.0 0.00099 18.5 0.0 4.9 4 1 0 4 4 4 3 Ras family MMR_HSR1 PF01926.18 OAJ06748.1 - 1.4e-06 28.2 0.0 0.00045 20.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.1 OAJ06748.1 - 1.7e-06 28.0 0.5 0.017 15.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.1 OAJ06748.1 - 7.8e-06 26.0 0.1 0.075 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ06748.1 - 2.3e-05 24.4 1.2 0.11 12.5 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain EF-hand_6 PF13405.1 OAJ06748.1 - 5.3e-05 22.7 4.7 0.012 15.3 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain ABC_tran PF00005.22 OAJ06748.1 - 0.00012 22.4 0.0 0.099 12.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 OAJ06748.1 - 0.00013 21.8 0.6 0.25 11.1 0.0 2.8 3 0 0 3 3 2 2 Dynamin family EF-hand_1 PF00036.27 OAJ06748.1 - 0.00015 20.8 2.1 0.088 12.1 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.1 OAJ06748.1 - 0.00016 21.1 0.1 0.051 13.1 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ06748.1 - 0.00037 19.7 0.4 0.0025 17.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 OAJ06748.1 - 0.00044 19.9 0.2 0.76 9.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AIG1 PF04548.11 OAJ06748.1 - 0.0036 16.4 0.2 0.0061 15.6 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MobB PF03205.9 OAJ06748.1 - 0.0042 16.7 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 OAJ06748.1 - 0.0062 16.5 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 OAJ06748.1 - 0.011 15.0 3.5 0.068 12.5 0.1 2.5 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.1 OAJ06748.1 - 0.027 14.8 0.0 2.8 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 OAJ06748.1 - 0.027 13.9 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 OAJ06748.1 - 0.029 14.5 0.0 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ06748.1 - 0.039 13.8 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 OAJ06748.1 - 0.051 13.0 0.0 6.5 6.1 0.0 3.2 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 OAJ06748.1 - 0.054 12.9 0.1 4.1 6.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 OAJ06748.1 - 0.061 12.7 0.1 4.6 6.6 0.0 2.8 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 OAJ06748.1 - 0.064 12.6 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 OAJ06748.1 - 0.072 13.2 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 OAJ06748.1 - 0.077 12.6 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 OAJ06748.1 - 0.078 12.4 0.1 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 OAJ06748.1 - 0.081 12.5 0.1 17 4.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 OAJ06748.1 - 0.083 11.8 0.0 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_24 PF13479.1 OAJ06748.1 - 0.095 12.2 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 OAJ06748.1 - 0.11 13.3 0.0 12 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 OAJ06748.1 - 0.11 11.9 0.1 21 4.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein EF-hand_10 PF14788.1 OAJ06748.1 - 0.22 11.2 0.9 1.3 8.7 0.1 2.1 2 0 0 2 2 2 0 EF hand DUF815 PF05673.8 OAJ06748.1 - 0.28 10.0 0.3 7 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 OAJ06748.1 - 0.34 11.2 0.3 16 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 OAJ06748.1 - 0.34 10.8 0.0 14 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 OAJ06748.1 - 0.5 9.5 0.0 4.3 6.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Adeno_IVa2 PF02456.10 OAJ06748.1 - 0.51 8.9 0.0 0.93 8.0 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein DPBB_1 PF03330.13 OAJ06749.1 - 9e-07 28.8 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ06749.1 - 0.00075 19.1 0.3 0.0013 18.3 0.2 1.3 1 0 0 1 1 1 1 Barwin family Lipase_3 PF01764.20 OAJ06751.1 - 1.1e-13 50.9 0.0 2.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PsaL PF02605.10 OAJ06751.1 - 0.0096 15.4 0.1 0.037 13.5 0.0 1.9 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI DUF3040 PF11239.3 OAJ06752.1 - 0.18 11.8 0.3 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Mito_carr PF00153.22 OAJ06754.1 - 5.7e-50 167.0 6.9 3.2e-17 61.9 0.0 4.1 3 1 1 4 4 4 3 Mitochondrial carrier protein Zn_clus PF00172.13 OAJ06756.1 - 3.1e-07 30.1 4.0 4.9e-07 29.5 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ISN1 PF06437.6 OAJ06758.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Histone PF00125.19 OAJ06759.1 - 2.2e-11 43.6 0.0 2.8e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 OAJ06759.1 - 6.7e-06 26.0 0.0 9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 OAJ06759.1 - 5.4e-05 23.0 0.0 7.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T PF15511.1 OAJ06759.1 - 0.00086 18.6 0.0 0.00098 18.4 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 OAJ06759.1 - 0.0043 17.2 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF4095 PF13338.1 OAJ06759.1 - 0.0052 16.9 0.1 0.006 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4095) TFIID-31kDa PF02291.10 OAJ06759.1 - 0.0073 16.1 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HTH_17 PF12728.2 OAJ06759.1 - 0.22 11.8 1.3 0.85 9.9 0.1 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain PIF1 PF05970.9 OAJ06761.1 - 2.6e-106 355.6 0.0 3.6e-106 355.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ06761.1 - 1.7e-53 181.1 0.4 3.3e-53 180.1 0.3 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ06761.1 - 1.2e-06 26.6 0.0 1.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 OAJ06761.1 - 3.7e-06 26.6 0.0 7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 OAJ06761.1 - 6.5e-05 23.0 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAJ06761.1 - 0.029 14.1 0.1 0.09 12.5 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 OAJ06761.1 - 0.16 11.5 0.0 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L36 PF00444.13 OAJ06762.1 - 3.7e-21 74.8 7.8 6.5e-21 74.0 5.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 ACOX PF01756.14 OAJ06763.1 - 8.4e-22 77.4 0.0 8.8e-17 61.0 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 OAJ06763.1 - 5.9e-19 68.5 0.1 2.2e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 OAJ06763.1 - 3e-09 37.1 0.1 1.7e-08 34.7 0.0 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ06763.1 - 3.3e-09 36.1 0.8 6.6e-09 35.1 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain PIP5K PF01504.13 OAJ06764.1 - 6e-43 146.7 0.0 9e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Fer2 PF00111.22 OAJ06764.1 - 0.18 11.5 1.6 0.45 10.3 1.1 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain CDC50 PF03381.10 OAJ06765.1 - 1.4e-74 250.8 0.0 1.8e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aldo_ket_red PF00248.16 OAJ06766.1 - 1.1e-29 103.1 0.0 1.7e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3077 PF11275.3 OAJ06766.1 - 0.11 12.4 0.1 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) p450 PF00067.17 OAJ06767.1 - 1.6e-45 155.4 0.0 2e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rifin_STEVOR PF02009.11 OAJ06767.1 - 0.0019 17.9 2.6 0.0034 17.0 1.8 1.4 1 0 0 1 1 1 1 Rifin/stevor family adh_short PF00106.20 OAJ06768.1 - 7.1e-08 32.5 4.4 1.5e-06 28.2 1.4 2.9 2 2 1 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.1 OAJ06768.1 - 2.1e-07 31.1 0.0 2.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 OAJ06768.1 - 1.7e-06 27.6 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 OAJ06768.1 - 0.11 11.5 0.0 0.4 9.7 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3377 PF11857.3 OAJ06769.1 - 0.0049 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) SKG6 PF08693.5 OAJ06769.1 - 0.084 12.1 0.8 0.2 11.0 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Apt1 PF10351.4 OAJ06769.1 - 0.46 9.2 1.7 0.84 8.4 1.2 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain FLO_LFY PF01698.11 OAJ06769.1 - 6.9 5.4 5.7 16 4.2 3.9 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein ANTH PF07651.11 OAJ06770.1 - 3.9e-49 166.8 0.2 6.2e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 OAJ06770.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 OAJ06770.1 - 0.011 15.8 136.4 0.012 15.6 3.4 7.3 4 2 3 7 7 7 0 Domain of unknown function (DUF1720) Vfa1 PF08432.5 OAJ06770.1 - 0.15 12.0 7.2 0.26 11.3 5.0 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GAGA_bind PF06217.7 OAJ06770.1 - 2.2 8.1 8.7 0.82 9.5 4.1 1.6 1 1 1 2 2 2 0 GAGA binding protein-like family DUF1510 PF07423.6 OAJ06770.1 - 7.3 5.8 13.3 12 5.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vps16_C PF04840.7 OAJ06771.1 - 1.7e-66 224.3 1.7 3.8e-35 121.3 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.8 OAJ06771.1 - 1.9e-51 174.8 0.0 2.4e-20 72.4 0.0 4.2 4 0 0 4 4 4 3 Vps16, N-terminal region Asparaginase PF00710.15 OAJ06780.1 - 3.9e-126 420.1 0.0 5.8e-126 419.6 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 OAJ06780.1 - 5.1e-12 44.9 1.4 1.6e-06 27.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 OAJ06780.1 - 6.6e-12 45.2 1.2 1.6e-07 31.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ06780.1 - 1.4e-11 44.5 0.0 2.9e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ06780.1 - 7.4e-11 42.2 0.1 3.3e-09 37.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ06780.1 - 5.2e-09 35.4 0.9 2e-05 24.3 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat DUF1215 PF06744.7 OAJ06782.1 - 0.067 12.8 1.0 3.4 7.3 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1215) FimP PF09766.4 OAJ06784.1 - 1.8e-27 96.3 10.9 2.5e-27 95.9 7.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein V_ATPase_I PF01496.14 OAJ06784.1 - 1.2 6.9 7.9 1.7 6.4 5.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 OAJ06784.1 - 6.3 5.7 11.6 1.9 7.4 5.6 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Drf_FH1 PF06346.7 OAJ06786.1 - 0.053 13.0 12.6 0.076 12.5 8.7 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 ketoacyl-synt PF00109.21 OAJ06787.1 - 4.8e-23 81.9 1.0 9.1e-23 81.0 0.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 OAJ06787.1 - 2.9e-15 56.1 0.0 6.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 OAJ06787.1 - 3.3e-15 55.9 0.7 8.7e-15 54.6 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short_C2 PF13561.1 OAJ06787.1 - 2.7e-10 40.4 0.0 5.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.18 OAJ06787.1 - 0.0012 17.9 0.1 0.0026 16.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ribosomal_L35p PF01632.14 OAJ06788.1 - 5.6e-11 42.1 1.0 8.3e-11 41.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 PI-PLC-X PF00388.14 OAJ06789.1 - 8.8e-49 164.6 0.0 1.7e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ06789.1 - 1.2e-37 128.4 0.0 2.7e-37 127.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 OAJ06789.1 - 3.2e-08 33.4 0.1 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 OAJ06789.1 - 7.7e-05 22.4 0.0 0.044 13.6 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_8 PF13833.1 OAJ06789.1 - 0.00034 20.1 0.4 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair Serglycin PF04360.7 OAJ06789.1 - 0.0041 16.8 3.4 0.012 15.3 1.4 2.4 2 0 0 2 2 2 1 Serglycin GDPD PF03009.12 OAJ06789.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family AAA PF00004.24 OAJ06790.1 - 5e-52 175.5 0.0 7.2e-39 133.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.12 OAJ06790.1 - 3.6e-10 39.3 0.1 2.1e-08 33.6 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 OAJ06790.1 - 7.1e-08 32.5 0.0 1.8e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 OAJ06790.1 - 2.9e-07 31.3 0.1 0.0067 17.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 OAJ06790.1 - 8.3e-07 28.2 0.3 0.023 13.7 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 OAJ06790.1 - 8.4e-07 28.0 0.1 0.025 13.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 OAJ06790.1 - 8.7e-07 28.8 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ06790.1 - 9e-07 29.0 0.1 0.0012 19.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ06790.1 - 1.2e-06 28.4 0.0 0.061 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ06790.1 - 3.9e-06 26.6 0.0 0.0019 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 OAJ06790.1 - 7.6e-06 25.5 0.9 0.12 12.1 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 OAJ06790.1 - 9.5e-06 25.9 0.1 0.0074 16.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 OAJ06790.1 - 1.1e-05 25.5 0.1 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Mg_chelatase PF01078.16 OAJ06790.1 - 1.1e-05 24.6 0.3 0.006 15.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.12 OAJ06790.1 - 0.00011 21.1 0.0 0.066 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 OAJ06790.1 - 0.00012 22.2 0.0 0.097 12.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 OAJ06790.1 - 0.00013 21.4 1.0 0.031 13.7 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein CDC48_N PF02359.13 OAJ06790.1 - 0.00013 21.8 0.0 0.0005 19.9 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.1 OAJ06790.1 - 0.00014 21.3 0.6 0.54 9.6 0.0 3.3 2 1 1 3 3 3 2 AAA domain KTI12 PF08433.5 OAJ06790.1 - 0.00022 20.5 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_28 PF13521.1 OAJ06790.1 - 0.00022 21.2 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 OAJ06790.1 - 0.0003 19.9 0.2 0.65 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 OAJ06790.1 - 0.0016 17.6 0.5 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 OAJ06790.1 - 0.0019 17.7 0.0 0.82 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 OAJ06790.1 - 0.0019 18.4 0.4 0.038 14.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter UPF0079 PF02367.12 OAJ06790.1 - 0.0028 17.2 0.2 0.54 9.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 OAJ06790.1 - 0.0031 17.1 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 OAJ06790.1 - 0.0036 16.9 0.2 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 OAJ06790.1 - 0.0068 16.0 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 OAJ06790.1 - 0.0069 16.0 1.5 2.2 7.9 0.0 3.2 4 0 0 4 4 3 1 NACHT domain CPT PF07931.7 OAJ06790.1 - 0.0085 15.7 0.1 0.08 12.5 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 OAJ06790.1 - 0.012 14.8 0.0 0.82 8.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 OAJ06790.1 - 0.015 15.0 0.4 34 4.0 0.0 3.4 2 2 2 4 4 3 0 Archaeal ATPase AAA_30 PF13604.1 OAJ06790.1 - 0.015 14.8 0.0 0.88 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 OAJ06790.1 - 0.038 12.8 0.1 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.11 OAJ06790.1 - 0.055 12.6 0.5 1.1 8.3 0.1 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.4 OAJ06790.1 - 0.082 11.8 0.1 0.72 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 OAJ06790.1 - 0.095 12.7 0.0 12 5.9 0.0 3.3 3 1 0 3 3 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 OAJ06790.1 - 0.32 9.8 0.4 11 4.8 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Myb_DNA-binding PF00249.26 OAJ06791.1 - 2.8e-10 40.0 0.7 5.7e-10 39.0 0.5 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ06791.1 - 1.2e-06 28.5 0.5 3.1e-06 27.1 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pox_A_type_inc PF04508.7 OAJ06792.1 - 0.0023 17.5 2.1 0.09 12.6 0.1 2.5 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Dynactin_p22 PF07426.6 OAJ06792.1 - 0.036 13.3 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Dynactin subunit p22 FAD-oxidase_C PF02913.14 OAJ06792.1 - 0.075 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Lebercilin PF15619.1 OAJ06792.1 - 0.16 11.3 0.9 0.38 10.1 0.6 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Nse4_C PF08743.5 OAJ06794.1 - 6.1e-26 90.2 0.0 1.8e-25 88.7 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 OAJ06794.1 - 2.9e-09 36.6 0.3 6.8e-09 35.4 0.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ADH_N PF08240.7 OAJ06795.1 - 1.7e-28 98.5 1.2 1.7e-28 98.5 0.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ06795.1 - 3.2e-25 88.1 1.1 4.2e-25 87.8 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ06795.1 - 0.0016 19.3 0.3 0.0032 18.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Corona_NS2 PF04753.7 OAJ06795.1 - 0.12 12.3 0.4 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 ACP_syn_III_C PF08541.5 OAJ06795.1 - 0.15 12.1 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MDM31_MDM32 PF08118.6 OAJ06797.1 - 2.4e-120 402.3 2.5 3.4e-55 187.4 0.0 3.1 2 1 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins EthD PF07110.6 OAJ06798.1 - 0.00066 20.5 0.8 0.38 11.7 0.2 2.5 2 1 0 2 2 2 2 EthD domain UDPGP PF01704.13 OAJ06799.1 - 2.3e-184 612.7 0.2 2.7e-184 612.5 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Gp-FAR-1 PF05823.7 OAJ06799.1 - 0.017 15.1 1.4 0.026 14.4 0.2 1.9 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Snf7 PF03357.16 OAJ06801.1 - 5.9e-45 152.7 12.3 7e-45 152.4 8.5 1.0 1 0 0 1 1 1 1 Snf7 Mod_r PF07200.8 OAJ06801.1 - 0.0089 15.9 6.0 0.026 14.4 2.6 2.0 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein DMPK_coil PF08826.5 OAJ06801.1 - 0.039 13.8 0.3 0.039 13.8 0.2 3.4 4 0 0 4 4 4 0 DMPK coiled coil domain like NuA4 PF09340.5 OAJ06801.1 - 0.04 13.5 1.3 0.075 12.6 0.1 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 EURL PF06937.6 OAJ06801.1 - 0.22 10.9 3.2 0.27 10.6 2.2 1.1 1 0 0 1 1 1 0 EURL protein Prefoldin_2 PF01920.15 OAJ06801.1 - 0.62 9.8 16.8 3 7.6 0.1 3.6 2 1 0 3 3 3 0 Prefoldin subunit Rho_Binding PF08912.6 OAJ06801.1 - 0.66 10.3 6.6 4.7 7.5 0.3 2.4 2 0 0 2 2 2 0 Rho Binding DUF848 PF05852.6 OAJ06801.1 - 0.98 9.2 9.3 1.3 8.9 4.9 2.2 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) V_ATPase_I PF01496.14 OAJ06801.1 - 1.2 6.8 9.1 4.3 5.0 5.2 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 OAJ06801.1 - 1.5 8.5 4.0 7.9 6.1 0.0 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD THP2 PF09432.5 OAJ06801.1 - 1.7 8.5 5.7 1.4 8.7 1.4 2.4 1 1 0 2 2 2 0 Tho complex subunit THP2 FlxA PF14282.1 OAJ06801.1 - 2.2 8.2 11.4 2.9 7.8 4.7 2.3 1 1 1 2 2 2 0 FlxA-like protein DUF342 PF03961.8 OAJ06801.1 - 3.2 6.0 8.7 1.3 7.4 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 OAJ06801.1 - 9.5 5.8 12.7 18 4.8 0.1 2.2 1 1 1 2 2 2 0 Mnd1 family GATA PF00320.22 OAJ06802.1 - 3.4e-05 23.1 5.9 0.00014 21.0 2.6 2.4 1 1 1 2 2 2 2 GATA zinc finger ADK_lid PF05191.9 OAJ06802.1 - 0.069 12.8 1.6 0.14 11.8 1.1 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid Glyco_hydro_92 PF07971.7 OAJ06803.1 - 3.5e-110 369.0 0.0 5.3e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1744 PF08490.7 OAJ06804.1 - 7.5e-121 403.4 0.0 1.1e-120 402.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 OAJ06804.1 - 7.4e-62 209.0 0.0 1.2e-61 208.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 OAJ06804.1 - 5.8e-19 68.2 0.0 1.7e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 OAJ06804.1 - 5e-09 35.9 0.1 1.9e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 OAJ06804.1 - 6e-06 26.1 0.0 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily HSP9_HSP12 PF04119.7 OAJ06805.1 - 7e-19 67.6 4.6 7e-19 67.6 3.2 1.6 2 0 0 2 2 2 1 Heat shock protein 9/12 FtsJ PF01728.14 OAJ06806.1 - 3.1e-44 151.1 0.0 4.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Amidase PF01425.16 OAJ06807.1 - 8.2e-58 196.2 1.8 1.3e-54 185.7 1.0 2.0 2 0 0 2 2 2 2 Amidase DUF2830 PF11125.3 OAJ06807.1 - 0.032 13.9 2.9 4 7.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2830) DFP PF04127.10 OAJ06808.1 - 8.8e-20 71.0 0.0 2.9e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PIF1 PF05970.9 OAJ06811.1 - 4.4e-21 75.2 0.0 5.8e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ06811.1 - 1.6e-06 27.8 0.0 3.5e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ06811.1 - 0.0003 20.4 0.2 0.00055 19.6 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 OAJ06811.1 - 0.0023 18.0 0.1 0.01 15.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 OAJ06811.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 OAJ06811.1 - 0.015 14.4 0.2 0.092 11.8 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 OAJ06811.1 - 0.016 15.2 0.3 0.32 11.0 0.2 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 OAJ06811.1 - 0.04 13.4 2.1 2.7 7.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain DNA_binding_1 PF01035.15 OAJ06814.1 - 8.7e-22 76.6 0.2 1.2e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Actin PF00022.14 OAJ06817.1 - 1.3e-23 83.1 0.0 7.8e-19 67.3 0.0 3.4 3 1 0 3 3 3 3 Actin Cation_efflux PF01545.16 OAJ06818.1 - 1.1e-31 110.0 2.0 1.3e-31 109.7 1.4 1.1 1 0 0 1 1 1 1 Cation efflux family ECH PF00378.15 OAJ06819.1 - 3e-40 137.8 0.2 6.9e-40 136.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF334 PF03904.8 OAJ06819.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) MFS_1 PF07690.11 OAJ06820.1 - 2.4e-13 49.5 2.1 3.2e-13 49.1 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 OAJ06821.1 - 3.1e-10 39.3 7.1 4.6e-10 38.7 4.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ06821.1 - 7.5e-05 21.4 0.6 0.0001 21.0 0.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter SUR7 PF06687.7 OAJ06822.1 - 9.8e-21 74.2 7.0 1.3e-20 73.8 4.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 OAJ06822.1 - 4.6e-10 39.4 2.0 4.6e-10 39.4 1.4 2.2 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 OAJ06822.1 - 0.0016 18.3 0.8 0.18 11.7 0.2 2.3 2 0 0 2 2 2 1 CD20-like family DUF2561 PF10812.3 OAJ06822.1 - 0.015 14.8 0.5 0.053 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) MARVEL PF01284.18 OAJ06822.1 - 0.49 10.1 18.3 0.5 10.1 8.1 2.6 2 1 0 2 2 2 0 Membrane-associating domain Amastin PF07344.6 OAJ06822.1 - 0.77 9.3 0.0 0.77 9.3 0.0 2.7 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF3754 PF12576.3 OAJ06822.1 - 1.1 8.8 7.8 0.061 12.9 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2207 PF09972.4 OAJ06822.1 - 1.8 7.0 5.4 0.52 8.8 1.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Clc-like PF07062.7 OAJ06822.1 - 3.6 6.7 11.4 0.16 11.2 3.2 2.2 2 1 0 2 2 2 0 Clc-like Ribosomal_L18e PF00828.14 OAJ06823.1 - 9.3e-24 84.2 0.7 1.4e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Adap_comp_sub PF00928.16 OAJ06824.1 - 1.3e-90 303.0 0.0 1.8e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 OAJ06824.1 - 6.6e-08 32.3 0.1 1.1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Spt4 PF06093.8 OAJ06825.1 - 5.6e-21 74.2 0.0 6.2e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Skp1 PF01466.14 OAJ06826.1 - 4.3e-37 125.9 1.4 6.2e-37 125.4 1.0 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 OAJ06826.1 - 8.3e-19 67.4 0.0 1.7e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.26 OAJ06826.1 - 0.16 12.0 0.3 16 5.6 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain HsbA PF12296.3 OAJ06827.1 - 8.2e-13 48.2 5.8 1.1e-12 47.9 4.0 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ06827.1 - 0.0027 17.4 1.0 0.0034 17.0 0.7 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Ig_Tie2_1 PF10430.4 OAJ06827.1 - 0.14 12.5 0.1 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 Hydantoinase_A PF01968.13 OAJ06828.1 - 6.2e-88 294.6 0.4 3.6e-87 292.1 0.2 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 OAJ06828.1 - 3.1e-57 192.9 0.4 8.2e-55 185.0 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MARVEL PF01284.18 OAJ06829.1 - 6.4e-05 22.8 9.1 6.4e-05 22.8 6.3 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF3681 PF12442.3 OAJ06829.1 - 0.2 11.8 0.4 0.2 11.8 0.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3681) IF-2B PF01008.12 OAJ06831.1 - 7e-35 120.3 0.2 6.1e-32 110.7 0.0 2.9 3 0 0 3 3 3 2 Initiation factor 2 subunit family Daxx PF03344.10 OAJ06831.1 - 0.37 9.2 27.1 0.0098 14.4 11.0 2.1 2 0 0 2 2 2 0 Daxx Family BUD22 PF09073.5 OAJ06831.1 - 3.1 6.7 16.4 4.7 6.1 11.3 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 OAJ06831.1 - 9.6 3.9 23.6 0.15 9.9 10.0 1.9 2 0 0 2 2 2 0 Nop14-like family TspO_MBR PF03073.10 OAJ06832.1 - 1.5e-43 147.8 10.8 1.8e-43 147.6 7.5 1.0 1 0 0 1 1 1 1 TspO/MBR family Cyt-b5 PF00173.23 OAJ06833.1 - 1.4e-21 76.0 0.0 3.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 OAJ06833.1 - 3e-10 40.4 16.7 3e-10 40.4 11.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SHMT PF00464.14 OAJ06834.1 - 3.8e-167 555.7 0.0 4.4e-167 555.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 OAJ06834.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 OAJ06834.1 - 0.076 11.9 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II PDH PF02153.12 OAJ06835.1 - 7.4e-13 47.9 0.0 1.5e-12 47.0 0.0 1.5 2 0 0 2 2 2 1 Prephenate dehydrogenase F420_oxidored PF03807.12 OAJ06835.1 - 2.4e-07 31.0 0.0 5.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 OAJ06835.1 - 3.4e-05 23.7 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 OAJ06835.1 - 3.8e-05 23.8 0.0 7.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ06835.1 - 0.00021 20.4 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 OAJ06835.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 OAJ06835.1 - 0.0091 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 OAJ06835.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 OAJ06835.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Rossmann-like PF10727.4 OAJ06835.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 OAJ06835.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 OAJ06835.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribonuclease_T2 PF00445.13 OAJ06836.1 - 1.7e-33 115.8 0.0 5.2e-33 114.2 0.0 1.6 1 1 1 2 2 2 1 Ribonuclease T2 family IDO PF01231.13 OAJ06837.1 - 5.2e-43 147.0 0.0 7.7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase BA14K PF07886.6 OAJ06837.1 - 0.51 10.0 1.7 9 6.0 0.0 2.5 2 0 0 2 2 2 0 BA14K-like protein SNF2_N PF00176.18 OAJ06838.1 - 2.1e-62 210.6 9.3 1.2e-36 126.0 0.2 3.1 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 OAJ06838.1 - 2.3e-10 40.1 0.0 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SDA1 PF05285.7 OAJ06838.1 - 0.0035 16.6 18.5 0.0035 16.6 12.8 2.6 2 1 0 2 2 2 1 SDA1 BUD22 PF09073.5 OAJ06838.1 - 0.16 10.9 43.9 1 8.3 17.1 2.3 2 0 0 2 2 2 0 BUD22 Ndc1_Nup PF09531.5 OAJ06838.1 - 1.2 7.5 4.5 1.8 6.8 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt5_N PF11942.3 OAJ06838.1 - 1.5 9.5 32.9 0.9 10.2 3.9 4.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal ESSS PF10183.4 OAJ06840.1 - 4.8e-24 84.7 0.0 6.5e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3432 PF11914.3 OAJ06840.1 - 0.38 10.7 6.2 2.1 8.4 3.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) UAA PF08449.6 OAJ06841.1 - 1.2e-64 218.1 9.9 5.2e-58 196.3 6.5 2.7 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 OAJ06841.1 - 9.8e-06 25.6 4.1 9.8e-06 25.6 2.9 4.6 3 2 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 OAJ06841.1 - 6.8e-05 22.5 13.9 0.0047 16.5 6.6 3.2 2 1 0 2 2 2 2 Triose-phosphate Transporter family UPF0546 PF10639.4 OAJ06841.1 - 0.00064 19.5 2.2 0.64 9.8 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 Nuc_sug_transp PF04142.10 OAJ06841.1 - 0.002 17.2 6.6 0.054 12.6 0.0 2.5 3 0 0 3 3 3 2 Nucleotide-sugar transporter EmrE PF13536.1 OAJ06841.1 - 1.3 9.2 22.7 0.021 15.0 4.0 3.5 3 1 0 3 3 3 0 Multidrug resistance efflux transporter RRM_1 PF00076.17 OAJ06842.1 - 2.1e-14 52.8 0.0 2.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06842.1 - 7.4e-11 41.8 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06842.1 - 8.9e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF883 PF05957.8 OAJ06843.1 - 0.038 14.3 0.3 0.038 14.3 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) FAM176 PF14851.1 OAJ06843.1 - 0.2 11.3 1.5 0.9 9.2 1.0 2.1 1 0 0 1 1 1 0 FAM176 family tRNA-synt_2d PF01409.15 OAJ06844.1 - 4.5e-44 150.4 0.1 1.6e-25 89.6 0.1 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 OAJ06844.1 - 6.2e-24 83.9 0.0 1.4e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Asn_synthase PF00733.16 OAJ06845.1 - 2.8e-49 167.9 0.1 4.4e-49 167.2 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 OAJ06845.1 - 1.9e-10 40.5 0.0 4.7e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 OAJ06845.1 - 1.2e-09 38.1 0.0 2.9e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 OAJ06845.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein NAD_synthase PF02540.12 OAJ06845.1 - 0.12 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 NAD synthase tRNA-synt_1c PF00749.16 OAJ06846.1 - 8.5e-75 251.3 0.0 1.2e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.13 OAJ06846.1 - 0.23 10.0 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) DSPn PF14671.1 OAJ06856.1 - 2.1e-31 108.7 0.0 1.6e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 OAJ06856.1 - 6.4e-14 51.6 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ06856.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 OAJ06856.1 - 0.0098 15.9 0.1 0.023 14.7 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate PV-1 PF06637.6 OAJ06856.1 - 0.017 13.7 2.1 0.027 13.0 1.5 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Y_phosphatase3 PF13350.1 OAJ06856.1 - 0.096 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family COG2 PF06148.6 OAJ06856.1 - 0.24 11.2 1.1 0.44 10.4 0.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Docking PF08990.6 OAJ06857.1 - 0.02 14.1 2.1 0.05 12.8 1.4 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking Transposase_21 PF02992.9 OAJ06858.1 - 6.7e-19 67.8 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Sld5 PF05916.6 OAJ06859.1 - 1.7e-19 70.0 0.0 2.5e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DDHD PF02862.12 OAJ06860.1 - 6.5 6.4 8.6 4.3 7.0 3.8 2.3 2 1 0 2 2 2 0 DDHD domain C2 PF00168.25 OAJ06861.1 - 7.8e-22 76.9 0.0 2.4e-15 56.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain zf-RING_2 PF13639.1 OAJ06862.1 - 0.00015 21.5 7.0 0.00027 20.7 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 OAJ06862.1 - 0.00015 21.3 3.2 0.00027 20.5 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 OAJ06862.1 - 0.0041 16.7 5.3 0.0071 15.9 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ06862.1 - 0.25 11.0 4.7 0.46 10.2 3.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PP2C_C PF07830.8 OAJ06863.1 - 0.00018 21.5 1.3 27 4.9 0.0 4.6 4 0 0 4 4 4 2 Protein serine/threonine phosphatase 2C, C-terminal domain Trypan_PARP PF05887.6 OAJ06863.1 - 0.00025 20.8 52.1 0.00025 20.8 36.1 4.9 3 1 2 5 5 5 1 Procyclic acidic repetitive protein (PARP) DUF2603 PF10788.4 OAJ06863.1 - 0.015 15.0 0.4 1.1e+02 2.5 0.0 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF2603) HSP70 PF00012.15 OAJ06864.1 - 4.9e-156 520.1 0.1 7.1e-156 519.6 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 OAJ06864.1 - 7.4e-10 37.9 0.1 1.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 OAJ06864.1 - 0.044 13.3 0.5 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DER1 PF04511.10 OAJ06866.1 - 3.1e-46 157.3 1.2 3.5e-46 157.1 0.8 1.0 1 0 0 1 1 1 1 Der1-like family RhoGAP PF00620.22 OAJ06867.1 - 8e-38 129.4 0.0 1.9e-37 128.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 OAJ06867.1 - 6.9e-18 65.0 0.0 1.6e-15 57.3 0.0 3.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 OAJ06867.1 - 9.8e-10 38.4 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.1 OAJ06867.1 - 9e-05 22.6 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 OAJ06867.1 - 0.00093 19.3 0.0 0.16 12.1 0.0 2.6 2 0 0 2 2 2 1 PH domain NblA PF04485.7 OAJ06867.1 - 0.032 14.0 0.1 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Phycobilisome degradation protein nblA COPI_C PF06957.6 OAJ06867.1 - 9.1 4.6 4.6 15 3.9 3.2 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus R3H PF01424.17 OAJ06868.1 - 7e-10 38.4 0.4 1.7e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 OAJ06868.1 - 0.00096 19.0 9.8 0.00096 19.0 6.8 8.1 10 0 0 10 10 10 3 NF-X1 type zinc finger DUF3554 PF12074.3 OAJ06869.1 - 1 8.6 0.4 1.7 7.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) Ferric_reduct PF01794.14 OAJ06870.1 - 3.5e-15 56.2 9.2 1.1e-14 54.5 6.4 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ06870.1 - 2.5e-10 40.4 0.0 3.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ06870.1 - 1.9e-08 34.0 0.0 3.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Zn_clus PF00172.13 OAJ06872.1 - 1e-07 31.7 9.3 2e-07 30.7 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-SNARE_C PF12352.3 OAJ06873.1 - 7.6e-14 51.5 0.6 1.6e-13 50.5 0.2 1.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 OAJ06873.1 - 1.5e-06 27.7 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Ribosomal_L7Ae PF01248.21 OAJ06874.1 - 3.6e-26 90.5 0.1 4.3e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ06874.1 - 0.0033 17.2 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 OAJ06874.1 - 0.019 14.7 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Herpes_U34 PF04541.8 OAJ06874.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus virion protein U34 Paf67 PF10255.4 OAJ06875.1 - 1.7e-156 521.1 0.0 2.4e-156 520.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 OAJ06875.1 - 0.00049 19.8 0.4 0.0045 16.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ06875.1 - 0.0059 16.1 0.0 0.054 13.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HOOK PF05622.7 OAJ06876.1 - 1.2e-50 172.1 38.0 1.2e-50 172.1 26.3 3.7 2 1 2 4 4 4 2 HOOK protein Laminin_II PF06009.7 OAJ06876.1 - 0.0044 16.7 13.7 0.0044 16.7 9.5 6.2 2 2 3 6 6 6 2 Laminin Domain II Rootletin PF15035.1 OAJ06876.1 - 0.0064 16.4 16.6 0.0064 16.4 11.5 5.0 3 2 2 5 5 5 1 Ciliary rootlet component, centrosome cohesion Strep_SA_rep PF06696.6 OAJ06876.1 - 0.061 13.1 6.4 0.27 11.0 0.5 3.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Filament PF00038.16 OAJ06876.1 - 0.094 12.1 83.7 0.028 13.8 8.4 4.5 2 2 3 5 5 5 0 Intermediate filament protein Reo_sigmaC PF04582.7 OAJ06876.1 - 0.14 11.2 24.2 0.86 8.7 1.0 3.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Cellulase PF00150.13 OAJ06877.1 - 1.7e-14 53.7 7.5 5.5e-14 52.0 5.2 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Abhydrolase_6 PF12697.2 OAJ06878.1 - 2.2e-32 112.7 3.9 3.6e-32 112.0 0.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ06878.1 - 5.8e-20 71.8 0.0 1.2e-18 67.5 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ06878.1 - 1.2e-14 54.2 0.5 1.8e-10 40.7 0.0 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 OAJ06878.1 - 2.8e-06 27.0 0.1 0.00027 20.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 OAJ06878.1 - 4.5e-05 23.2 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.8 OAJ06878.1 - 5.1e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 OAJ06878.1 - 7.3e-05 22.3 0.0 1.7 8.0 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 OAJ06878.1 - 0.00028 20.3 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 OAJ06878.1 - 0.0017 16.9 0.0 0.0029 16.1 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 OAJ06878.1 - 0.0052 15.9 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 OAJ06878.1 - 0.012 14.8 0.0 0.094 11.9 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 OAJ06878.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 OAJ06878.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_4 PF08386.5 OAJ06878.1 - 0.045 13.6 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.7 OAJ06878.1 - 0.072 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase PF07224.6 OAJ06878.1 - 0.074 11.8 0.0 0.45 9.2 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase Hydrolase_4 PF12146.3 OAJ06878.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF676 PF05057.9 OAJ06878.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 OAJ06878.1 - 0.098 12.8 0.2 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Toprim PF01751.17 OAJ06878.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Toprim domain Chlorophyllase2 PF12740.2 OAJ06878.1 - 0.14 11.0 0.0 0.35 9.7 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme Nop14 PF04147.7 OAJ06879.1 - 0.036 12.0 6.9 0.04 11.8 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family ubiquitin PF00240.18 OAJ06879.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family SDA1 PF05285.7 OAJ06879.1 - 0.29 10.3 6.4 0.33 10.1 4.4 1.1 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.13 OAJ06879.1 - 1.7 7.7 6.5 2.9 6.9 4.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 OAJ06879.1 - 4.6 6.4 6.9 6.9 5.8 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 OAJ06879.1 - 5.6 5.3 13.0 8.6 4.7 9.0 1.2 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 OAJ06879.1 - 9.9 4.7 10.6 14 4.3 7.4 1.1 1 0 0 1 1 1 0 Paf1 Arabinose_Iso_C PF11762.3 OAJ06880.1 - 0.2 11.2 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain ECSIT PF06239.6 OAJ06881.1 - 0.98 8.2 2.2 52 2.6 0.2 3.1 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway RVT_2 PF07727.9 OAJ06882.1 - 3.3e-81 271.8 0.0 4.2e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 OAJ06882.1 - 0.0033 16.8 0.0 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) VIT1 PF01988.14 OAJ06883.1 - 2.2e-64 216.8 4.6 2.7e-64 216.5 3.2 1.1 1 0 0 1 1 1 1 VIT family KAR9 PF08580.5 OAJ06884.1 - 0.0009 17.6 0.2 0.0009 17.6 0.1 4.7 3 2 1 4 4 4 1 Yeast cortical protein KAR9 GAS2 PF02187.12 OAJ06884.1 - 0.046 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain Acyltransferase PF01553.16 OAJ06885.1 - 1.5e-16 60.0 0.1 2.5e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase Tic20 PF09685.5 OAJ06885.1 - 0.072 13.0 1.8 0.18 11.7 1.3 1.6 1 0 0 1 1 1 0 Tic20-like protein Cellulase PF00150.13 OAJ06886.1 - 1.7e-08 34.0 0.0 5.6e-07 29.0 0.1 2.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) LEA_2 PF03168.8 OAJ06887.1 - 0.0056 17.0 0.1 0.025 14.9 0.0 2.1 1 1 1 2 2 2 1 Late embryogenesis abundant protein Neurensin PF14927.1 OAJ06887.1 - 0.044 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Neurensin Cation_efflux PF01545.16 OAJ06888.1 - 5.3e-46 156.9 6.3 9.4e-46 156.1 4.4 1.4 1 1 0 1 1 1 1 Cation efflux family Hex_IIIa PF02455.11 OAJ06888.1 - 0.092 11.4 2.3 0.14 10.8 1.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) IF4E PF01652.13 OAJ06889.1 - 1.4e-48 164.5 0.0 3.3e-48 163.3 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E BRF1 PF07741.8 OAJ06889.1 - 0.77 10.0 8.5 7.1 6.9 0.2 2.6 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Apolipoprotein PF01442.13 OAJ06890.1 - 0.00082 18.9 0.1 0.0027 17.2 0.1 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 OAJ06890.1 - 0.0015 18.3 7.4 0.11 12.2 0.8 2.9 1 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus NAAA-beta PF15508.1 OAJ06890.1 - 0.014 15.7 0.2 0.35 11.2 0.0 2.5 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Serine_rich PF08824.5 OAJ06890.1 - 0.034 13.8 0.2 0.085 12.5 0.1 1.7 1 1 0 1 1 1 0 Serine rich protein interaction domain IZUMO PF15005.1 OAJ06890.1 - 0.042 13.8 0.3 5.1 7.1 0.0 2.3 1 1 1 2 2 2 0 Izumo sperm-egg fusion SF-assemblin PF06705.6 OAJ06890.1 - 0.055 12.6 0.1 0.071 12.2 0.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin RRF PF01765.14 OAJ06890.1 - 0.069 12.6 0.7 0.18 11.2 0.5 1.7 1 1 0 1 1 1 0 Ribosome recycling factor ATP-synt_B PF00430.13 OAJ06890.1 - 0.078 12.7 0.3 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) AIP3 PF03915.8 OAJ06890.1 - 0.092 11.6 0.4 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Prominin PF05478.6 OAJ06890.1 - 0.23 8.9 1.6 1.2 6.5 0.2 1.9 1 1 1 2 2 2 0 Prominin DUF2407 PF10302.4 OAJ06891.1 - 1.6e-12 47.4 0.5 5.7e-11 42.4 0.2 2.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 OAJ06891.1 - 6.2e-11 42.3 4.6 8.4e-09 35.4 2.2 3.4 2 1 0 2 2 2 1 DUF2407 C-terminal domain ubiquitin PF00240.18 OAJ06891.1 - 0.0063 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family IATP PF04568.7 OAJ06891.1 - 1.8 8.6 4.7 2 8.5 1.4 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP RRM_1 PF00076.17 OAJ06892.1 - 4.2e-18 64.7 0.0 6.6e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06892.1 - 2.4e-15 56.2 0.6 6.5e-15 54.8 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06892.1 - 1.8e-08 34.1 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc34 PF05158.7 OAJ06893.1 - 1.5e-79 267.5 2.7 2.7e-69 233.8 0.1 2.5 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 OAJ06893.1 - 0.03 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.14 OAJ06893.1 - 0.031 13.9 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.1 OAJ06893.1 - 0.077 12.8 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix Nop53 PF07767.6 OAJ06894.1 - 0.00046 19.3 3.4 0.00072 18.6 2.3 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DEAD PF00270.24 OAJ06895.1 - 1.6e-10 40.7 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ06895.1 - 4.1e-10 39.3 0.0 4.6e-09 36.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ06895.1 - 0.0068 16.2 0.4 0.043 13.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TPR_11 PF13414.1 OAJ06896.1 - 2e-07 30.5 0.9 0.016 14.8 0.4 2.5 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 OAJ06896.1 - 1.6e-06 27.2 1.3 7.3e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.1 OAJ06896.1 - 0.0014 18.5 1.1 0.68 9.9 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ06896.1 - 0.0041 16.9 4.9 0.13 12.2 0.9 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ06896.1 - 0.0089 15.6 1.3 1.3 8.7 0.5 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 OAJ06896.1 - 0.065 13.0 4.2 0.1 12.4 0.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat AATF-Che1 PF13339.1 OAJ06896.1 - 0.56 10.3 8.5 1.2 9.3 0.4 3.4 3 2 0 3 3 3 0 Apoptosis antagonizing transcription factor Usp PF00582.21 OAJ06897.1 - 9.3e-19 68.0 0.1 9.3e-19 68.0 0.1 3.2 4 0 0 4 4 4 1 Universal stress protein family DUF2422 PF10337.4 OAJ06897.1 - 0.39 9.4 0.6 0.61 8.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) AAA PF00004.24 OAJ06898.1 - 5.2e-32 110.8 0.0 1.2e-31 109.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 OAJ06898.1 - 3.8e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 OAJ06898.1 - 7.6e-08 32.5 0.2 3.8e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 OAJ06898.1 - 1.9e-06 28.6 0.0 4.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 OAJ06898.1 - 1.9e-06 27.4 0.1 0.037 13.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 OAJ06898.1 - 4.5e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ06898.1 - 4.6e-06 26.5 0.1 1.9e-05 24.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 OAJ06898.1 - 9.1e-06 25.5 0.3 0.00074 19.2 0.2 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 OAJ06898.1 - 2.3e-05 24.7 0.0 4.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ06898.1 - 7.9e-05 22.3 0.0 0.00027 20.6 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_24 PF13479.1 OAJ06898.1 - 0.0001 21.9 0.0 0.00027 20.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 OAJ06898.1 - 0.00031 20.6 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 OAJ06898.1 - 0.00033 20.3 0.1 0.0027 17.4 0.1 2.2 1 1 0 1 1 1 1 NACHT domain PhoH PF02562.11 OAJ06898.1 - 0.00064 19.0 0.0 0.21 10.8 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein UPF0079 PF02367.12 OAJ06898.1 - 0.00091 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 OAJ06898.1 - 0.002 17.7 0.5 0.007 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ06898.1 - 0.0025 17.5 0.1 0.0062 16.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 OAJ06898.1 - 0.0026 16.8 0.0 0.01 14.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 OAJ06898.1 - 0.003 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 OAJ06898.1 - 0.003 16.9 0.0 0.0075 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 OAJ06898.1 - 0.0041 16.1 0.0 0.0078 15.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 OAJ06898.1 - 0.0041 17.0 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAJ06898.1 - 0.0046 16.5 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 OAJ06898.1 - 0.0048 15.9 0.0 0.85 8.5 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain DUF815 PF05673.8 OAJ06898.1 - 0.0055 15.6 0.0 0.04 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 OAJ06898.1 - 0.006 15.5 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 OAJ06898.1 - 0.0062 16.1 0.1 0.044 13.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 OAJ06898.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_23 PF13476.1 OAJ06898.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAJ06898.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 OAJ06898.1 - 0.03 13.5 0.0 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 OAJ06898.1 - 0.059 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 OAJ06898.1 - 0.066 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain SPC25 PF06703.6 OAJ06898.1 - 0.074 12.6 0.2 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) KTI12 PF08433.5 OAJ06898.1 - 0.088 11.9 0.5 0.32 10.1 0.0 2.1 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_3 PF07726.6 OAJ06898.1 - 0.098 12.2 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF59 PF01883.14 OAJ06899.1 - 2.8e-09 36.8 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF59 CENP-T PF15511.1 OAJ06900.1 - 5.2 6.2 27.9 6 5.9 19.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T eRF1_1 PF03463.10 OAJ06901.1 - 1.9e-53 179.5 0.0 2.9e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 OAJ06901.1 - 5.5e-23 81.3 0.0 1e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 OAJ06901.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_anti-codon PF01336.20 OAJ06901.1 - 0.14 12.0 0.1 0.62 9.9 0.0 2.1 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Tubulin PF00091.20 OAJ06903.1 - 1.1e-73 247.5 0.0 2.3e-73 246.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 OAJ06903.1 - 3.3e-41 140.2 0.0 6.1e-41 139.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 OAJ06903.1 - 0.00024 21.1 0.0 0.00059 19.8 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 OAJ06903.1 - 0.025 14.0 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain DUF3321 PF11968.3 OAJ06904.1 - 1.2e-42 146.0 0.0 2.4e-25 89.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase (DUF3321) CENP-B_dimeris PF09026.5 OAJ06904.1 - 0.096 12.9 9.8 0.13 12.5 1.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 OAJ06904.1 - 0.13 11.7 4.8 1.1 8.7 0.6 2.2 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 OAJ06904.1 - 0.17 11.1 10.2 0.57 9.4 1.2 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Hexapep PF00132.19 OAJ06905.1 - 2.3e-05 23.6 1.2 0.052 13.0 0.0 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 OAJ06905.1 - 0.055 12.7 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase Methyltransf_31 PF13847.1 OAJ06906.1 - 4.1e-12 45.9 0.2 7.2e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ06906.1 - 7.5e-11 42.6 0.1 1.9e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 OAJ06906.1 - 2.2e-10 40.1 0.1 3.7e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 OAJ06906.1 - 1.2e-08 34.8 0.0 2.9e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ06906.1 - 1.2e-07 32.1 0.0 2.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ06906.1 - 2.6e-07 30.7 0.0 5.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 OAJ06906.1 - 1.3e-06 27.7 0.0 1.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 OAJ06906.1 - 6.3e-06 25.3 0.0 8.6e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 OAJ06906.1 - 1.3e-05 24.5 0.1 2.8e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 OAJ06906.1 - 2.8e-05 22.9 0.0 3.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 OAJ06906.1 - 3.5e-05 24.2 0.0 7.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ06906.1 - 5.5e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAJ06906.1 - 0.00097 19.1 0.2 0.0016 18.4 0.1 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 OAJ06906.1 - 0.0019 17.7 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 OAJ06906.1 - 0.0066 15.9 0.1 0.0098 15.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 OAJ06906.1 - 0.019 14.0 0.1 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 OAJ06906.1 - 0.021 14.3 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 OAJ06906.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 OAJ06906.1 - 0.067 12.3 1.1 0.28 10.3 0.4 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TehB MetW PF07021.7 OAJ06906.1 - 0.088 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 OAJ06906.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ferric_reduct PF01794.14 OAJ06907.1 - 6.6e-13 48.8 10.1 6.6e-13 48.8 7.0 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 OAJ06907.1 - 4.8e-09 36.0 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 OAJ06907.1 - 0.0017 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain IDO PF01231.13 OAJ06908.1 - 1e-118 396.4 0.0 1.1e-117 393.0 0.0 2.0 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase MIR PF02815.14 OAJ06909.1 - 5e-20 71.8 0.0 7.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 MIR domain Mg-por_mtran_C PF07109.6 OAJ06910.1 - 0.092 12.8 0.1 0.2 11.7 0.0 1.5 1 1 1 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus DUF1769 PF08588.5 OAJ06911.1 - 6.3e-17 61.2 0.3 1.1e-16 60.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) zf-C3HC4_3 PF13920.1 OAJ06912.1 - 1.1e-06 28.2 7.0 1.1e-06 28.2 4.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 OAJ06912.1 - 7.6 7.1 26.0 0.17 12.2 0.5 5.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type JmjC PF02373.17 OAJ06913.1 - 1.3e-39 134.9 0.1 2.6e-39 133.9 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 OAJ06913.1 - 1.8e-13 49.7 0.2 3.8e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 OAJ06913.1 - 3.6e-09 36.6 1.5 3.6e-09 36.6 1.0 3.0 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 OAJ06913.1 - 2.2e-08 34.0 9.6 2.6e-08 33.8 1.0 2.8 3 0 0 3 3 3 2 PHD-zinc-finger like domain RRM_1 PF00076.17 OAJ06914.1 - 1.8e-20 72.3 0.0 3.3e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ06914.1 - 1.2e-16 60.4 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ06914.1 - 3e-10 39.8 0.0 7.5e-10 38.5 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 OAJ06914.1 - 3.8e-09 36.7 20.6 2e-07 31.2 14.3 2.4 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MRC1 PF09444.5 OAJ06915.1 - 5.9e-15 55.8 26.5 5.9e-15 55.8 18.3 6.8 7 1 1 8 8 8 1 MRC1-like domain F-box-like PF12937.2 OAJ06916.1 - 0.0077 15.9 0.3 0.023 14.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRV_FeS PF05484.6 OAJ06916.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster RVT_1 PF00078.22 OAJ06918.1 - 9.7e-38 129.6 0.0 1.5e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ06918.1 - 2.4e-31 108.3 0.0 2.6e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.1 OAJ06918.1 - 1.5e-11 44.6 0.0 2.6e-05 24.6 0.0 3.8 4 0 0 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.1 OAJ06918.1 - 4.7e-07 29.5 0.6 0.022 14.5 0.0 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ06918.1 - 0.00023 21.0 0.0 0.62 10.0 0.0 2.6 2 0 0 2 2 2 2 Retroviral aspartyl protease LRV_FeS PF05484.6 OAJ06920.1 - 0.052 13.1 0.1 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 LRV protein FeS4 cluster WD40 PF00400.27 OAJ06922.1 - 2.7e-24 84.0 11.5 2.2e-07 30.4 0.0 7.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 OAJ06922.1 - 5.1e-22 78.3 4.2 1.5e-20 73.4 0.0 2.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ06922.1 - 8.9e-10 38.3 3.1 1e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 OAJ06922.1 - 1e-05 24.5 2.9 0.00012 20.9 1.0 2.4 2 0 0 2 2 2 1 Nup133 N terminal like WD40 PF00400.27 OAJ06928.1 - 3.3e-65 213.8 23.1 4.3e-12 45.4 0.3 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 OAJ06928.1 - 2.7e-08 32.4 8.1 0.52 8.3 0.0 5.8 2 1 4 6 6 6 6 Nucleoporin Nup120/160 eIF2A PF08662.6 OAJ06928.1 - 1.7e-07 31.1 0.0 0.0021 17.7 0.0 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 OAJ06928.1 - 0.024 12.8 0.0 0.067 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) TPD52 PF04201.10 OAJ06929.1 - 0.0059 16.3 0.6 0.083 12.6 0.0 2.4 2 0 0 2 2 2 1 Tumour protein D52 family TMEM237 PF15383.1 OAJ06929.1 - 0.037 13.1 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 Pkinase PF00069.20 OAJ06931.1 - 6.6e-65 218.8 0.0 3.5e-64 216.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06931.1 - 3.1e-34 118.2 0.0 7.4e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 OAJ06931.1 - 3.4e-27 93.9 18.2 3.9e-17 61.7 5.3 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 OAJ06931.1 - 3.6e-20 71.4 24.3 1.6e-10 40.5 7.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 OAJ06931.1 - 1.7e-08 34.8 2.3 6.2e-08 33.0 1.6 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 OAJ06931.1 - 0.0029 16.6 0.0 0.006 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like UPF0547 PF10571.4 OAJ06931.1 - 2.4 7.9 6.9 7.2 6.4 0.1 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 FYVE_2 PF02318.11 OAJ06931.1 - 3.7 7.4 16.6 15 5.4 4.9 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger Tcp11 PF05794.8 OAJ06932.1 - 2e-63 214.6 0.1 8.4e-48 163.1 0.5 5.0 4 1 0 4 4 4 4 T-complex protein 11 Acatn PF13000.2 OAJ06933.1 - 2.3e-140 468.7 29.4 7.4e-71 239.3 8.9 4.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 NAC PF01849.13 OAJ06935.1 - 9.4e-19 66.7 0.1 1.5e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 NAC domain ATP-synt_G PF04718.10 OAJ06936.1 - 5.2e-18 65.5 1.3 1.7e-17 63.9 0.0 2.1 1 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit ApoC-I PF04691.7 OAJ06936.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF2413 PF10310.4 OAJ06936.1 - 0.31 9.7 8.6 0.42 9.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2564 PF10819.3 OAJ06936.1 - 2.4 8.3 8.7 4.3 7.5 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2564) Pkinase PF00069.20 OAJ06937.1 - 3.8e-72 242.5 0.0 4.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06937.1 - 7.2e-31 107.1 0.0 8.8e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ06937.1 - 0.00056 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ06937.1 - 0.001 18.1 0.0 0.0031 16.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ06937.1 - 0.004 16.1 0.0 0.029 13.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 OAJ06937.1 - 0.05 12.9 0.1 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Glyco_hydro_15 PF00723.16 OAJ06938.1 - 1.4e-80 271.0 0.1 1.9e-80 270.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CS PF04969.11 OAJ06939.1 - 4.4e-07 30.3 0.0 7.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 CS domain ATP-synt_D PF01813.12 OAJ06940.1 - 2.7e-66 222.8 3.5 2.7e-66 222.8 2.4 1.4 2 0 0 2 2 2 1 ATP synthase subunit D Sigma70_ner PF04546.8 OAJ06940.1 - 3.9 7.0 12.3 9.3 5.7 5.1 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region zf-C2H2 PF00096.21 OAJ06941.1 - 0.053 13.8 0.7 0.11 12.9 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Gag_p24 PF00607.15 OAJ06941.1 - 0.14 11.6 0.0 0.9 9.0 0.0 2.0 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) ORC6 PF05460.8 OAJ06942.1 - 0.065 12.3 5.2 0.069 12.2 3.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2413 PF10310.4 OAJ06942.1 - 0.89 8.2 6.1 0.98 8.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF566 PF04484.7 OAJ06942.1 - 5 6.5 7.3 5.9 6.3 5.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cyclin_N PF00134.18 OAJ06944.1 - 4.9e-38 129.5 1.3 1e-36 125.3 0.6 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ06944.1 - 1.1e-25 89.8 0.3 2.5e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain TPR_20 PF14561.1 OAJ06944.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 OAJ06945.1 - 2.6e-55 186.7 0.0 5.5e-55 185.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 OAJ06945.1 - 2.7e-34 117.3 0.0 7.8e-34 115.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 OAJ06945.1 - 5.4e-29 99.8 0.0 1.2e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 OAJ06945.1 - 2.5e-22 78.5 0.1 6.9e-22 77.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ06945.1 - 2.8e-12 46.5 0.0 8.2e-12 45.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 adh_short PF00106.20 OAJ06946.1 - 5.6e-19 68.6 0.2 8.1e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ06946.1 - 4.1e-09 36.3 0.1 7.3e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ06946.1 - 5.5e-06 26.3 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 OAJ06946.1 - 0.00014 21.8 0.2 0.00075 19.5 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 OAJ06946.1 - 0.00088 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 OAJ06946.1 - 0.014 15.0 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 OAJ06946.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 YjeF-related protein N-terminus NAD_Gly3P_dh_N PF01210.18 OAJ06946.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CBF PF03914.12 OAJ06947.1 - 3.1e-34 117.7 0.6 2.2e-33 115.0 0.0 2.9 2 1 0 2 2 2 1 CBF/Mak21 family Proteasom_PSMB PF10508.4 OAJ06947.1 - 0.047 11.9 0.6 0.18 10.0 0.1 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Baculo_PEP_C PF04513.7 OAJ06948.1 - 0.0024 17.6 4.7 0.019 14.7 0.1 3.1 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus HOASN PF14515.1 OAJ06948.1 - 1.8 8.9 7.7 2.5 8.5 0.1 3.0 2 1 1 3 3 3 0 Haem-oxygenase-associated N-terminal helices DEAD PF00270.24 OAJ06949.1 - 5.3e-12 45.5 0.0 5.3e-12 45.5 0.0 2.2 2 1 0 2 2 1 1 DEAD/DEAH box helicase Ycf1 PF05758.7 OAJ06949.1 - 5.5e-05 21.1 4.7 7.3e-05 20.7 3.2 1.1 1 0 0 1 1 1 1 Ycf1 Helicase_C PF00271.26 OAJ06949.1 - 0.00031 20.5 0.0 0.00031 20.5 0.0 2.5 2 1 0 2 2 1 1 Helicase conserved C-terminal domain Otopetrin PF03189.8 OAJ06949.1 - 0.013 14.4 1.1 0.019 13.9 0.7 1.2 1 0 0 1 1 1 0 Otopetrin Spore_coat_CotO PF14153.1 OAJ06949.1 - 0.021 14.2 25.2 0.041 13.3 17.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO LMBR1 PF04791.11 OAJ06949.1 - 0.12 10.9 2.8 0.17 10.4 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4175 PF13779.1 OAJ06949.1 - 0.25 9.0 61.8 0.47 8.0 42.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mem_trans PF03547.13 OAJ06949.1 - 0.26 9.5 1.8 0.39 8.9 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4638 PF15472.1 OAJ06949.1 - 1.2 8.6 16.6 2.5 7.6 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RR_TM4-6 PF06459.7 OAJ06949.1 - 1.6 8.5 19.0 3.4 7.4 13.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 OAJ06949.1 - 2.1 7.3 13.4 3.7 6.4 9.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF342 PF03961.8 OAJ06949.1 - 2.4 6.4 15.3 4.1 5.6 9.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1510 PF07423.6 OAJ06949.1 - 4.4 6.6 23.5 8.7 5.6 16.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 OAJ06949.1 - 5.2 4.6 24.8 8.4 3.9 17.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 OAJ06949.1 - 7.4 5.4 19.7 14 4.5 13.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_S10 PF00338.17 OAJ06950.1 - 6.2e-19 67.6 0.0 1.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pex14_N PF04695.8 OAJ06950.1 - 2.6 8.0 7.3 0.77 9.8 0.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fumble PF03630.9 OAJ06951.1 - 5.3e-111 370.7 1.1 3.6e-86 289.1 0.1 3.2 2 2 0 2 2 2 2 Fumble RNase_P_Rpp14 PF01900.14 OAJ06951.1 - 0.019 14.8 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 Rpp14/Pop5 family SPT6_acidic PF14632.1 OAJ06951.1 - 0.033 14.3 5.1 0.051 13.7 3.6 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2422 PF10337.4 OAJ06953.1 - 1.4e-89 301.0 2.5 1e-87 294.9 0.2 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 OAJ06953.1 - 2.3e-29 102.6 0.0 5.8e-29 101.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 OAJ06953.1 - 2.5e-08 33.9 19.1 2.5e-08 33.9 13.2 3.6 3 1 0 3 3 3 1 Fusaric acid resistance protein-like DUF1180 PF06679.7 OAJ06953.1 - 0.28 11.0 0.0 0.28 11.0 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1180) Med26 PF08711.6 OAJ06955.1 - 1.4e-09 37.3 0.1 2.3e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain FlaG PF03646.10 OAJ06955.1 - 0.079 13.1 0.1 0.094 12.8 0.0 1.2 1 0 0 1 1 1 0 FlaG protein GCR1_C PF12550.3 OAJ06956.1 - 4.7e-18 64.8 1.4 1.2e-17 63.5 1.0 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Glycoprotein_G PF00802.14 OAJ06957.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G PglZ PF08665.7 OAJ06957.1 - 0.34 10.5 5.9 0.57 9.8 0.0 2.6 1 1 1 2 2 2 0 PglZ domain Motile_Sperm PF00635.21 OAJ06959.1 - 8.6e-26 89.7 0.1 2e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 OAJ06959.1 - 0.0042 17.1 0.1 0.0087 16.1 0.1 1.5 1 0 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase FlxA PF14282.1 OAJ06959.1 - 0.021 14.7 0.4 0.055 13.4 0.3 1.7 1 0 0 1 1 1 0 FlxA-like protein DUF1178 PF06676.6 OAJ06959.1 - 0.27 11.4 1.8 3.8 7.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) PI-PLC-X PF00388.14 OAJ06961.1 - 1.5e-44 150.9 0.0 2.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 OAJ06961.1 - 1.1e-32 112.4 0.0 2.7e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 OAJ06961.1 - 0.063 13.1 0.4 5 7.0 0.1 2.4 2 0 0 2 2 2 0 C2 domain F-box-like PF12937.2 OAJ06963.1 - 7.1e-07 28.8 0.7 1.3e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ06963.1 - 0.0019 17.7 0.1 0.0057 16.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain BSP_II PF05432.6 OAJ06963.1 - 0.0046 16.2 21.1 0.0049 16.2 1.6 2.4 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) Nucleo_P87 PF07267.6 OAJ06963.1 - 0.57 8.8 1.8 0.92 8.1 1.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.1 OAJ06963.1 - 1.6 8.4 11.4 0.049 13.3 2.5 2.2 2 0 0 2 2 2 0 FAM176 family IncA PF04156.9 OAJ06963.1 - 1.7 8.1 5.2 3 7.4 3.6 1.3 1 0 0 1 1 1 0 IncA protein Nucleoplasmin PF03066.10 OAJ06963.1 - 6.9 6.1 10.5 20 4.6 7.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin DAO PF01266.19 OAJ06964.1 - 3.7e-12 45.8 0.0 1.3e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ06964.1 - 5.4e-12 45.5 0.2 1.1e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 OAJ06964.1 - 3.9e-06 26.8 0.0 5.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 OAJ06964.1 - 2.4e-05 23.6 0.0 0.00084 18.5 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 OAJ06964.1 - 7.5e-05 21.7 1.2 0.00012 21.0 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 OAJ06964.1 - 0.00013 22.2 2.8 0.001 19.4 0.9 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ06964.1 - 0.002 16.6 0.1 0.0028 16.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 OAJ06964.1 - 0.0028 16.3 0.8 0.7 8.4 0.4 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 OAJ06964.1 - 0.0049 15.9 2.1 0.0062 15.6 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 OAJ06964.1 - 0.0052 16.3 0.1 0.0088 15.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 OAJ06964.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 OAJ06964.1 - 0.015 15.0 0.2 0.028 14.1 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 OAJ06964.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 OAJ06964.1 - 0.043 13.2 1.0 0.094 12.1 0.7 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 OAJ06964.1 - 0.048 12.5 0.3 0.093 11.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 OAJ06964.1 - 0.063 13.3 0.1 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 OAJ06964.1 - 0.069 12.8 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Rossmann-like domain FAD_oxidored PF12831.2 OAJ06964.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 OAJ06964.1 - 0.13 11.6 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 OAJ06964.1 - 0.13 12.5 0.2 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 OAJ06964.1 - 0.19 11.4 0.9 0.4 10.4 0.2 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 OAJ06964.1 - 0.24 11.0 0.4 0.45 10.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 OAJ06964.1 - 0.31 9.8 2.5 0.24 10.1 0.5 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A CS PF04969.11 OAJ06965.1 - 1.7e-08 34.8 0.0 1.6e-06 28.5 0.0 2.6 2 0 0 2 2 2 2 CS domain tRNA-synt_1c PF00749.16 OAJ06966.1 - 1.2e-104 349.4 0.0 1.9e-104 348.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 OAJ06966.1 - 2.1e-36 125.2 0.1 3.3e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 OAJ06966.1 - 1.6e-05 25.3 0.1 4.4e-05 23.8 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 OAJ06966.1 - 0.0066 16.3 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.8 OAJ06966.1 - 0.048 13.4 0.5 0.13 12.0 0.4 1.7 1 0 0 1 1 1 0 DSS1/SEM1 family GST_C PF00043.20 OAJ06966.1 - 0.084 12.8 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bestrophin PF01062.16 OAJ06967.1 - 2.1e-27 95.8 0.1 5.4e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2580 PF10824.3 OAJ06968.1 - 1.1e-05 25.6 20.8 2.1 8.7 0.4 6.5 6 1 0 6 6 6 1 Protein of unknown function (DUF2580) DUF327 PF03885.8 OAJ06968.1 - 2.8e-05 23.9 3.7 13 5.6 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF327) Eco57I PF07669.6 OAJ06968.1 - 8.5e-05 22.8 2.7 6.8 7.0 0.0 4.0 4 0 0 4 4 3 0 Eco57I restriction-modification methylase Glyco_hydro_47 PF01532.15 OAJ06968.1 - 8.5e-05 21.3 0.0 8.3 4.9 0.0 4.0 4 0 0 4 4 4 0 Glycosyl hydrolase family 47 V-SNARE_C PF12352.3 OAJ06968.1 - 0.0003 20.7 0.0 18 5.4 0.0 3.9 4 0 0 4 4 3 0 Snare region anchored in the vesicle membrane C-terminus XkdW PF09636.5 OAJ06968.1 - 0.00033 20.5 13.3 4.6 7.1 0.0 5.7 6 0 0 6 6 6 0 XkdW protein ClpB_D2-small PF10431.4 OAJ06968.1 - 0.00062 19.6 1.1 39 4.2 0.0 5.5 5 0 0 5 5 5 0 C-terminal, D2-small domain, of ClpB protein Suf PF05843.9 OAJ06968.1 - 0.00074 19.3 0.9 1.2 8.8 0.0 3.3 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) Spo0A_C PF08769.6 OAJ06968.1 - 0.0033 17.2 13.7 2.8 7.8 0.3 5.8 5 1 0 5 5 5 1 Sporulation initiation factor Spo0A C terminal DUF4164 PF13747.1 OAJ06968.1 - 0.0056 16.7 34.3 0.15 12.2 1.3 7.6 7 3 2 10 10 8 3 Domain of unknown function (DUF4164) DUF148 PF02520.12 OAJ06968.1 - 0.0063 16.3 37.2 0.2 11.4 1.1 6.8 4 2 4 8 8 8 2 Domain of unknown function DUF148 Pox_A6 PF04924.7 OAJ06968.1 - 0.0068 15.2 9.0 9.6 4.8 0.1 4.8 5 0 0 5 5 5 0 Poxvirus A6 protein NPV_P10 PF05531.7 OAJ06968.1 - 0.01 16.0 20.8 3.4 7.9 0.0 6.9 6 1 0 6 6 6 0 Nucleopolyhedrovirus P10 protein NifZ PF04319.8 OAJ06968.1 - 0.033 13.5 0.8 64 3.0 0.0 4.0 4 0 0 4 4 4 0 NifZ domain HTH_AsnC-type PF13404.1 OAJ06968.1 - 0.033 13.7 0.9 12 5.5 0.0 4.8 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Syntaxin_2 PF14523.1 OAJ06968.1 - 0.034 14.1 13.5 3.4 7.7 0.0 5.6 5 1 1 6 6 6 0 Syntaxin-like protein DUF1778 PF08681.6 OAJ06968.1 - 0.042 13.6 23.3 12 5.7 0.1 8.0 8 0 0 8 8 8 0 Protein of unknown function (DUF1778) FBP PF07299.6 OAJ06968.1 - 0.064 12.5 0.2 0.064 12.5 0.1 6.0 3 1 2 6 6 6 0 Fibronectin-binding protein (FBP) SusD-like_3 PF14322.1 OAJ06968.1 - 0.089 12.8 7.5 2.1 8.3 0.2 4.2 4 0 0 4 4 4 0 Starch-binding associating with outer membrane Reo_sigmaC PF04582.7 OAJ06968.1 - 0.1 11.7 8.8 0.11 11.6 0.3 3.5 3 2 1 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 OAJ06968.1 - 0.2 11.4 24.2 1.5 8.6 0.2 6.2 6 0 0 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C10 PF01640.12 OAJ06968.1 - 0.27 11.0 0.0 34 4.1 0.0 3.6 5 0 0 5 5 5 0 Peptidase C10 family Scaffolding_pro PF11418.3 OAJ06968.1 - 0.47 10.8 9.8 27 5.1 0.0 5.5 6 0 0 6 6 6 0 Phi29 scaffolding protein HTH_24 PF13412.1 OAJ06968.1 - 0.52 9.7 8.4 7.9 5.9 0.1 5.5 7 0 0 7 7 5 0 Winged helix-turn-helix DNA-binding DUF937 PF06078.6 OAJ06968.1 - 1 9.5 7.5 5.3 7.2 0.0 3.9 3 3 0 3 3 3 0 Bacterial protein of unknown function (DUF937) DUF1539 PF07560.6 OAJ06968.1 - 1.3 8.9 12.8 4.9 7.0 0.2 5.3 4 2 1 6 6 6 0 Domain of Unknown Function (DUF1539) Apolipoprotein PF01442.13 OAJ06968.1 - 1.3 8.4 9.7 0.24 10.8 0.3 3.5 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Filament PF00038.16 OAJ06968.1 - 1.4 8.2 11.4 7.2 5.9 0.1 4.4 2 2 2 5 5 5 0 Intermediate filament protein SinI PF08671.5 OAJ06968.1 - 1.9 8.0 6.1 13 5.2 0.5 3.3 3 0 0 3 3 3 0 Anti-repressor SinI DUF763 PF05559.6 OAJ06968.1 - 4.7 6.0 9.0 31 3.3 0.2 4.0 1 1 1 4 4 4 0 Protein of unknown function (DUF763) HAP1_N PF04849.8 OAJ06968.1 - 5.1 5.9 13.2 13 4.5 0.0 4.9 5 1 0 6 6 6 0 HAP1 N-terminal conserved region TPR_6 PF13174.1 OAJ06968.1 - 5.9 7.5 6.4 1.5e+02 3.1 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat NifQ PF04891.7 OAJ06968.1 - 7 6.7 8.1 18 5.4 0.0 4.8 1 1 2 6 6 5 0 NifQ zf-ZPR1 PF03367.8 OAJ06969.1 - 1.3e-93 310.5 0.0 5.8e-46 155.5 0.0 3.2 2 1 1 3 3 3 3 ZPR1 zinc-finger domain zf-ribbon_3 PF13248.1 OAJ06969.1 - 0.0093 15.1 2.2 2.5 7.4 0.0 3.4 3 1 0 3 3 3 1 zinc-ribbon domain HypA PF01155.14 OAJ06969.1 - 0.011 15.4 2.3 0.87 9.2 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 OAJ06969.1 - 0.039 13.7 2.9 12 5.8 0.1 3.3 3 0 0 3 3 3 0 Double zinc ribbon DUF3935 PF13071.1 OAJ06969.1 - 0.23 11.8 0.0 0.54 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3935) DUF2688 PF10892.3 OAJ06969.1 - 0.37 10.4 2.6 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.5 OAJ06969.1 - 4.9 7.1 7.8 13 5.8 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain Isochorismatase PF00857.15 OAJ06970.1 - 1.8e-23 83.3 0.9 5.9e-15 55.6 0.1 2.7 1 1 1 2 2 2 2 Isochorismatase family 4HBT PF03061.17 OAJ06971.1 - 2e-17 63.0 0.9 8.6e-12 45.0 0.1 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Phytase-like PF13449.1 OAJ06972.1 - 1.5e-26 93.5 0.1 3.5e-26 92.2 0.1 1.6 1 1 0 1 1 1 1 Esterase-like activity of phytase TRM PF02005.11 OAJ06973.1 - 4.5e-114 381.2 0.0 1.5e-85 287.4 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase HEAT_2 PF13646.1 OAJ06974.1 - 4.4e-21 74.9 1.8 6.9e-06 26.2 0.0 7.4 3 3 7 10 10 10 7 HEAT repeats HEAT_EZ PF13513.1 OAJ06974.1 - 1.6e-19 69.7 21.2 8e-10 38.9 0.0 9.8 10 1 0 10 10 10 3 HEAT-like repeat HEAT PF02985.17 OAJ06974.1 - 7e-18 63.0 14.1 0.0024 17.8 0.0 9.6 11 0 0 11 11 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 OAJ06974.1 - 6.7e-11 42.4 0.0 0.0016 18.7 0.1 4.7 3 2 1 4 4 3 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 OAJ06974.1 - 5.6e-07 28.6 6.2 0.0054 15.5 0.0 4.1 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 OAJ06974.1 - 4.1e-06 26.6 0.1 2.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.2 OAJ06974.1 - 2.2e-05 24.4 0.1 0.0066 16.3 0.0 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 OAJ06974.1 - 0.00011 21.9 3.8 0.63 9.9 0.0 5.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 OAJ06974.1 - 0.003 17.4 0.3 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 OAJ06974.1 - 0.0063 16.4 0.1 1.9 8.4 0.0 3.4 2 1 0 2 2 2 1 Exportin 1-like protein RPAP3_C PF13877.1 OAJ06974.1 - 0.021 14.8 0.0 0.098 12.6 0.0 2.2 2 0 0 2 2 1 0 Potential Monad-binding region of RPAP3 Adaptin_N PF01602.15 OAJ06974.1 - 0.06 11.6 0.7 0.15 10.3 0.2 1.9 2 0 0 2 2 2 0 Adaptin N terminal region CLASP_N PF12348.3 OAJ06974.1 - 0.19 11.0 0.5 10 5.4 0.1 3.6 3 2 1 4 4 4 0 CLASP N terminal RNA_pol_3_Rpc31 PF11705.3 OAJ06974.1 - 0.9 9.4 8.6 1.6 8.6 6.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pkinase PF00069.20 OAJ06975.1 - 1e-65 221.5 0.0 1.2e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ06975.1 - 1.2e-33 116.3 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ06975.1 - 6.1e-05 22.1 0.0 8.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FAD_binding_2 PF00890.19 OAJ06975.1 - 0.0059 15.5 0.5 0.38 9.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Kdo PF06293.9 OAJ06975.1 - 0.036 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.22 OAJ06976.1 - 2.8e-16 58.9 0.6 1.7e-05 24.4 0.0 5.9 5 1 0 5 5 5 5 Mitochondrial carrier protein DUF605 PF04652.11 OAJ06976.1 - 9.5 5.5 25.4 0.97 8.7 14.2 1.9 2 0 0 2 2 2 0 Vta1 like XFP_N PF09364.5 OAJ06977.1 - 1.6e-126 421.9 0.2 3e-105 351.9 0.1 2.1 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.5 OAJ06977.1 - 2.2e-55 187.2 0.0 9.8e-55 185.1 0.0 1.9 1 1 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 OAJ06977.1 - 1e-50 171.8 0.0 1.7e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 OAJ06977.1 - 0.035 13.6 0.2 0.089 12.3 0.2 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1049 PF06305.6 OAJ06978.1 - 0.016 14.6 0.8 0.028 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) AF1Q PF15017.1 OAJ06978.1 - 1.1 9.2 4.7 1.8 8.4 3.3 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DRMBL PF07522.9 OAJ06979.1 - 1.8e-26 92.3 0.0 3.3e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ06979.1 - 6.2e-07 29.1 0.0 2.4e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 OAJ06979.1 - 0.017 14.7 0.3 0.038 13.6 0.2 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PET PF06297.9 OAJ06979.1 - 0.057 13.0 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 PET Domain PI3_PI4_kinase PF00454.22 OAJ06980.1 - 1.6e-51 175.0 0.0 2.6e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 OAJ06980.1 - 3e-28 98.8 0.0 6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 OAJ06980.1 - 6.3e-19 67.9 0.0 2.2e-18 66.1 0.0 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 OAJ06980.1 - 4.1e-09 35.7 0.0 9.8e-09 34.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 OAJ06980.1 - 0.00079 19.3 0.0 0.0026 17.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.1 OAJ06980.1 - 0.72 10.4 7.4 4 8.0 0.7 4.6 3 0 0 3 3 3 0 HEAT-like repeat WD40 PF00400.27 OAJ06981.1 - 1.4e-70 230.8 22.4 1.3e-07 31.1 0.1 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 OAJ06981.1 - 2.4e-19 69.2 0.3 4.3e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 OAJ06981.1 - 3.2e-07 28.8 0.9 0.67 8.0 0.0 4.5 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 OAJ06981.1 - 8.4e-05 21.4 0.3 17 4.0 0.0 5.4 6 0 0 6 6 6 1 Nup133 N terminal like Prog_receptor PF02161.10 OAJ06981.1 - 0.056 12.2 3.0 0.11 11.2 2.1 1.5 1 0 0 1 1 1 0 Progesterone receptor Nbas_N PF15492.1 OAJ06981.1 - 0.062 12.4 0.0 0.5 9.4 0.0 2.3 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal YTH PF04146.10 OAJ06982.1 - 2.2e-41 140.7 0.0 3.2e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RVT_1 PF00078.22 OAJ06987.1 - 0.0026 17.1 0.0 0.015 14.6 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BolA PF01722.13 OAJ06988.1 - 4.9e-17 61.6 0.1 8.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF282 PF03380.9 OAJ06989.1 - 0.019 14.7 2.2 0.035 13.8 0.2 2.4 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Ras PF00071.17 OAJ06990.1 - 2e-34 118.3 0.3 2.4e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ06990.1 - 2.6e-22 79.5 0.1 1.4e-21 77.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 OAJ06990.1 - 5.9e-08 32.1 0.3 7.7e-08 31.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 OAJ06990.1 - 6.9e-08 31.9 0.0 8.8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ06990.1 - 0.0002 20.8 0.1 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 OAJ06990.1 - 0.0019 16.9 8.7 0.032 12.9 0.3 2.8 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 OAJ06990.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ06990.1 - 0.058 12.6 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DLIC PF05783.6 OAJ06990.1 - 0.097 11.3 0.8 2.8 6.5 0.0 2.2 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) PHP_C PF13263.1 OAJ06990.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 PHP-associated Pex14_N PF04695.8 OAJ06990.1 - 0.11 12.5 2.0 0.2 11.6 1.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AMP-binding PF00501.23 OAJ06991.1 - 1.3e-83 280.6 0.0 1.9e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 OAJ06991.1 - 0.0008 20.3 0.0 0.0089 16.9 0.0 2.8 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain ThiF PF00899.16 OAJ06992.1 - 3.9e-41 140.0 0.1 5.7e-41 139.5 0.1 1.2 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 OAJ06992.1 - 8e-23 79.8 0.1 1.4e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 OAJ06992.1 - 1.3e-08 35.2 0.0 3.7e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 OAJ06992.1 - 3.5e-06 27.1 0.1 4.5e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ06992.1 - 3.7e-06 27.1 0.0 7.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.19 OAJ06992.1 - 0.024 13.5 0.1 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 OAJ06992.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GCV_H PF01597.14 OAJ06992.1 - 0.035 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Utp21 PF04192.7 OAJ06993.1 - 1.7e-51 174.6 0.0 2.8e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 OAJ06993.1 - 7.4e-11 41.5 6.2 0.06 13.2 0.1 7.1 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 OAJ06993.1 - 0.004 16.9 0.0 0.17 11.6 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 OAJ06993.1 - 0.028 13.9 0.0 5.9 6.4 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 OAJ06993.1 - 0.067 11.9 0.1 8.6 4.9 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like ATP-synt_B PF00430.13 OAJ06994.1 - 0.00097 18.9 0.4 0.0013 18.5 0.3 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Coiled-coil_56 PF09813.4 OAJ06994.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Acyl-CoA_dh_2 PF08028.6 OAJ06994.1 - 0.033 14.4 0.9 0.048 13.9 0.6 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TrbL PF04610.9 OAJ06994.1 - 0.12 12.0 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein AAA_5 PF07728.9 OAJ06995.1 - 7.5e-116 382.1 0.0 2.6e-20 72.5 0.0 10.4 9 1 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA PF00004.24 OAJ06995.1 - 2e-27 95.9 0.1 0.0039 17.3 0.0 7.8 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 OAJ06995.1 - 7.4e-25 87.6 0.0 0.0028 17.7 0.0 7.8 6 0 0 6 6 6 6 AAA domain AAA_3 PF07726.6 OAJ06995.1 - 9.8e-25 86.6 0.0 1.1e-07 31.5 0.0 7.5 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 OAJ06995.1 - 2.4e-17 63.1 0.3 0.047 13.5 0.0 7.8 6 1 0 6 6 6 4 AAA domain AAA_17 PF13207.1 OAJ06995.1 - 2.7e-17 63.7 0.1 0.21 12.4 0.0 7.6 6 0 0 6 6 6 4 AAA domain AAA_19 PF13245.1 OAJ06995.1 - 5.1e-17 61.3 8.3 0.0063 16.2 0.0 7.1 6 0 0 6 6 6 5 Part of AAA domain ABC_tran PF00005.22 OAJ06995.1 - 7.6e-17 61.8 0.9 0.0078 16.5 0.0 6.8 7 0 0 7 7 6 3 ABC transporter AAA_14 PF13173.1 OAJ06995.1 - 7.9e-16 58.1 0.0 0.0016 18.3 0.0 6.7 8 0 0 8 8 5 3 AAA domain Zeta_toxin PF06414.7 OAJ06995.1 - 2.1e-15 56.3 0.4 0.016 14.2 0.0 7.6 6 1 0 6 6 6 2 Zeta toxin AAA_18 PF13238.1 OAJ06995.1 - 2.2e-15 57.0 0.3 0.053 13.8 0.0 7.1 6 0 0 6 6 6 2 AAA domain Sigma54_activat PF00158.21 OAJ06995.1 - 2.3e-14 53.2 0.0 0.0083 15.6 0.0 5.7 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_16 PF13191.1 OAJ06995.1 - 2.3e-14 53.7 55.5 0.00014 21.9 0.4 12.0 10 4 1 11 11 8 5 AAA ATPase domain Sigma54_activ_2 PF14532.1 OAJ06995.1 - 6.3e-14 52.2 1.4 0.023 14.7 0.0 7.4 7 0 0 7 7 7 2 Sigma-54 interaction domain AAA_29 PF13555.1 OAJ06995.1 - 4.4e-12 45.3 0.3 0.18 11.3 0.0 6.1 6 0 0 6 6 6 3 P-loop containing region of AAA domain UPF0079 PF02367.12 OAJ06995.1 - 4.8e-12 45.5 1.1 0.037 13.6 0.0 6.2 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 OAJ06995.1 - 1.4e-11 44.3 3.3 0.0094 15.6 0.0 6.2 5 0 0 5 5 5 3 NACHT domain AAA_28 PF13521.1 OAJ06995.1 - 1.8e-11 44.2 5.1 1.1 9.2 0.0 6.9 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 OAJ06995.1 - 2.2e-11 43.1 7.0 0.11 11.3 0.0 6.6 6 0 0 6 6 6 2 Type II/IV secretion system protein Miro PF08477.8 OAJ06995.1 - 4e-11 43.4 0.1 1.9 9.0 0.0 6.7 6 0 0 6 6 6 2 Miro-like protein AAA_25 PF13481.1 OAJ06995.1 - 8.5e-11 41.6 15.4 0.13 11.6 0.0 7.3 7 0 0 7 7 6 3 AAA domain RNA_helicase PF00910.17 OAJ06995.1 - 7.2e-10 39.0 0.8 1.5 9.0 0.0 6.7 6 0 0 6 6 6 1 RNA helicase Mg_chelatase PF01078.16 OAJ06995.1 - 3.3e-09 36.2 5.1 0.19 10.8 0.1 7.6 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 OAJ06995.1 - 7e-09 34.9 0.7 0.25 10.2 0.0 5.7 6 0 0 6 6 5 1 Protein of unknown function (DUF815) MobB PF03205.9 OAJ06995.1 - 7e-09 35.5 2.4 0.38 10.4 0.0 6.3 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 OAJ06995.1 - 9.2e-09 34.6 2.8 0.041 13.0 0.0 5.5 6 0 0 6 6 6 2 Protein of unknown function, DUF258 PduV-EutP PF10662.4 OAJ06995.1 - 9e-07 28.4 3.3 0.24 10.8 0.0 5.5 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 OAJ06995.1 - 6.7e-06 25.9 0.0 2.2 7.9 0.0 5.6 6 0 0 6 6 5 1 Archaeal ATPase AAA_24 PF13479.1 OAJ06995.1 - 1.1e-05 25.1 0.7 5.6 6.4 0.0 5.7 6 0 0 6 6 6 0 AAA domain cobW PF02492.14 OAJ06995.1 - 4.3e-05 23.0 7.4 1.6 8.1 0.0 5.6 6 0 0 6 6 5 1 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 OAJ06995.1 - 5.6e-05 22.3 1.0 6.4 5.8 0.0 5.0 5 0 0 5 5 5 0 KaiC AAA_7 PF12775.2 OAJ06995.1 - 5.7e-05 22.3 1.5 0.18 10.8 0.0 4.5 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 MMR_HSR1 PF01926.18 OAJ06995.1 - 0.00026 20.9 0.0 17 5.3 0.0 5.8 6 0 0 6 6 5 0 50S ribosome-binding GTPase SRP54 PF00448.17 OAJ06995.1 - 0.00026 20.5 5.6 0.6 9.5 0.0 5.2 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain ResIII PF04851.10 OAJ06995.1 - 0.00037 20.3 2.5 1.5 8.5 0.0 4.5 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit ArgK PF03308.11 OAJ06995.1 - 0.0009 18.0 0.6 3.2 6.4 0.0 3.4 3 0 0 3 3 3 0 ArgK protein NTPase_1 PF03266.10 OAJ06995.1 - 0.0011 18.7 4.2 4.8 6.8 0.0 5.4 5 0 0 5 5 5 0 NTPase AAA_23 PF13476.1 OAJ06995.1 - 0.0012 19.2 28.8 0.0017 18.6 0.0 7.4 8 1 0 8 8 6 2 AAA domain PhoH PF02562.11 OAJ06995.1 - 0.0014 17.9 3.8 3.6 6.7 0.1 4.2 4 0 0 4 4 4 0 PhoH-like protein ATP_bind_1 PF03029.12 OAJ06995.1 - 0.003 17.1 1.9 9.3 5.7 0.0 4.6 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Rad17 PF03215.10 OAJ06995.1 - 0.0044 15.7 0.3 2.1 6.9 0.0 3.9 5 0 0 5 5 4 1 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 OAJ06995.1 - 0.0058 16.6 0.1 7.1 6.4 0.0 4.2 4 0 0 4 4 4 0 AAA domain TIP49 PF06068.8 OAJ06995.1 - 0.012 14.3 5.9 2.3 6.8 0.0 4.4 5 0 0 5 5 5 0 TIP49 C-terminus AAA_6 PF12774.2 OAJ06995.1 - 0.024 14.1 0.2 28 4.1 0.0 4.2 5 0 0 5 5 3 0 Hydrolytic ATP binding site of dynein motor region D1 Dynamin_N PF00350.18 OAJ06995.1 - 0.045 13.5 0.6 51 3.6 0.0 4.9 4 0 0 4 4 4 0 Dynamin family DUF4218 PF13960.1 OAJ06995.1 - 0.059 12.8 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Herpes_Helicase PF02689.9 OAJ06995.1 - 0.49 8.0 0.0 17 2.9 0.0 2.4 2 0 0 2 2 2 0 Helicase AAA_15 PF13175.1 OAJ06995.1 - 5.9 5.8 0.0 1.7e+02 1.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain DAG_kinase_N PF14513.1 OAJ06996.1 - 0.079 13.1 0.3 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus JAB PF01398.16 OAJ06997.1 - 9.8e-27 92.9 0.1 1.5e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 OAJ06997.1 - 2.3e-06 27.1 0.0 4.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 OAJ06997.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) SIN1 PF05422.7 OAJ06998.1 - 1.1e-24 86.8 0.0 2e-14 53.0 0.0 2.6 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) Paf1 PF03985.8 OAJ07000.1 - 6.8e-37 127.2 40.0 3.1e-32 111.8 0.0 5.2 3 2 2 5 5 5 2 Paf1 RVT_1 PF00078.22 OAJ07001.1 - 8.4e-31 106.9 0.0 1.5e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 OAJ07001.1 - 1e-12 48.5 0.0 2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 OAJ07001.1 - 2.8e-12 46.3 0.0 6e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 OAJ07001.1 - 6.3e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 OAJ07001.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DUF2890 PF11081.3 OAJ07002.1 - 3.1 7.8 16.5 0.4 10.7 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) Abhydrolase_6 PF12697.2 OAJ07004.1 - 3.5e-22 79.3 0.2 6.9e-22 78.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ07004.1 - 5.6e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ07004.1 - 6.5e-06 25.8 0.0 0.071 12.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 OAJ07004.1 - 0.003 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF900 PF05990.7 OAJ07004.1 - 0.036 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) CENP-B_dimeris PF09026.5 OAJ07004.1 - 3.9 7.7 6.9 22 5.3 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Kei1 PF08552.6 OAJ07005.1 - 4.1e-46 157.0 0.2 5.2e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 CEP19 PF14933.1 OAJ07007.1 - 1.4 9.2 10.3 2.2 8.5 1.8 2.1 2 0 0 2 2 2 0 CEP19-like protein DUF4407 PF14362.1 OAJ07007.1 - 4.2 6.2 10.5 2.2 7.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GRP PF07172.6 OAJ07007.1 - 9.6 6.7 39.2 0.27 11.7 8.1 3.1 2 1 1 3 3 3 0 Glycine rich protein family rRNA_proc-arch PF13234.1 OAJ07009.1 - 9.8e-79 264.2 0.1 1.5e-78 263.6 0.1 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 OAJ07009.1 - 9.8e-57 191.0 1.2 9.8e-57 191.0 0.9 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 OAJ07009.1 - 1.2e-22 80.1 0.0 3.5e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07009.1 - 2.2e-06 27.4 0.0 6.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ07009.1 - 0.075 12.8 0.0 0.65 9.8 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ07009.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF1686 PF07937.6 OAJ07010.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) DUF3328 PF11807.3 OAJ07010.1 - 0.089 12.4 0.4 0.16 11.6 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Phage_integrase PF00589.17 OAJ07011.1 - 8.1e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.12 OAJ07011.1 - 0.001 19.1 0.4 0.0076 16.3 0.1 2.5 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 OAJ07011.1 - 0.11 12.8 0.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain PIF1 PF05970.9 OAJ07012.1 - 6.3e-12 45.1 0.0 1.2e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase DUF4188 PF13826.1 OAJ07015.1 - 0.14 12.2 1.0 0.29 11.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) CAF-1_p150 PF11600.3 OAJ07015.1 - 0.25 10.7 29.5 0.51 9.6 20.4 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3508 PF12018.3 OAJ07015.1 - 0.63 8.9 10.6 0.093 11.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) DUF2462 PF09495.5 OAJ07015.1 - 1.1 10.0 14.4 1.4 9.6 8.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) FUSC PF04632.7 OAJ07015.1 - 2.7 6.3 10.1 3.3 6.0 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Transket_pyr PF02779.19 OAJ07017.1 - 9.3e-38 129.4 0.1 1.4e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 OAJ07017.1 - 5.8e-27 94.0 0.0 3.2e-26 91.6 0.0 2.1 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_L10 PF00466.15 OAJ07018.1 - 0.0007 19.4 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L10 La PF05383.12 OAJ07019.1 - 2.9e-17 62.1 0.0 4.5e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 La domain SF3b10 PF07189.6 OAJ07020.1 - 3.6e-28 97.1 0.0 4.1e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TOM20_plant PF06552.7 OAJ07020.1 - 0.15 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 NAD_kinase PF01513.16 OAJ07021.1 - 1.8e-65 220.5 0.0 7.2e-65 218.5 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase RXT2_N PF08595.6 OAJ07021.1 - 6.9 6.4 14.0 2.9 7.6 7.1 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CoA_binding_2 PF13380.1 OAJ07022.1 - 1.5e-31 108.9 0.1 1.8e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 OAJ07022.1 - 4.3e-05 23.9 0.0 6.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Stn1 PF10451.4 OAJ07023.1 - 0.0019 17.0 0.0 0.0044 15.9 0.0 1.5 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 OAJ07023.1 - 0.0041 16.9 0.1 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain APOBEC_N PF08210.6 OAJ07023.1 - 0.076 12.6 0.2 3.7 7.1 0.1 2.2 2 0 0 2 2 2 0 APOBEC-like N-terminal domain PAP2 PF01569.16 OAJ07024.1 - 3.5e-26 91.3 3.7 3.5e-26 91.3 2.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF4203 PF13886.1 OAJ07024.1 - 0.0022 17.5 0.1 0.0022 17.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4203) Nucleoporin_FG PF13634.1 OAJ07025.1 - 7.6e-06 26.1 84.1 0.0044 17.2 51.9 3.7 2 1 0 2 2 2 1 Nucleoporin FG repeat region Abhydrolase_3 PF07859.8 OAJ07025.1 - 0.015 14.8 1.3 0.16 11.5 0.2 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Cyclin_N PF00134.18 OAJ07027.1 - 3.2e-41 139.8 0.2 1e-40 138.2 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ07027.1 - 3e-28 98.1 0.0 1e-27 96.4 0.0 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M28 PF04389.12 OAJ07027.1 - 3.7e-25 88.7 0.0 9.2e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 VHS PF00790.14 OAJ07028.1 - 3.9e-40 136.7 0.0 1e-39 135.3 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 OAJ07028.1 - 1.1e-20 73.4 0.3 2.7e-20 72.2 0.2 1.6 1 0 0 1 1 1 1 GAT domain DPM2 PF07297.7 OAJ07029.1 - 5.3e-25 87.4 0.2 6.4e-25 87.2 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 OAJ07029.1 - 2.5e-05 23.8 0.1 3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 PIG-P FecCD PF01032.13 OAJ07029.1 - 0.011 14.5 0.3 0.017 13.9 0.2 1.2 1 1 0 1 1 1 0 FecCD transport family ApbA PF02558.11 OAJ07029.1 - 0.032 13.6 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sensor PF13796.1 OAJ07029.1 - 0.043 13.4 0.8 0.048 13.2 0.5 1.1 1 0 0 1 1 1 0 Putative sensor DUF1206 PF06724.6 OAJ07029.1 - 0.059 13.1 3.4 1.5 8.6 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) DUF4013 PF13197.1 OAJ07029.1 - 0.063 12.6 1.9 0.083 12.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DJ-1_PfpI PF01965.19 OAJ07030.1 - 2e-27 95.4 0.0 3e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 OAJ07030.1 - 4.2e-13 48.8 0.0 6.2e-13 48.3 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase NuA4 PF09340.5 OAJ07031.1 - 1.3e-19 69.5 0.0 4.5e-19 67.8 0.0 1.9 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 OB_NTP_bind PF07717.11 OAJ07032.1 - 1.2e-27 95.9 0.0 2.7e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 OAJ07032.1 - 1.8e-26 92.1 0.1 4.3e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 OAJ07032.1 - 5.6e-12 45.3 0.0 1.4e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 OAJ07032.1 - 7.6e-05 21.7 0.0 0.00022 20.2 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 OAJ07032.1 - 0.00017 21.1 0.2 0.0004 19.9 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 OAJ07032.1 - 0.00021 21.4 0.1 0.00056 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 OAJ07032.1 - 0.026 14.8 0.2 0.36 11.1 0.1 2.4 1 1 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 OAJ07032.1 - 0.044 13.4 0.1 0.091 12.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 OAJ07032.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 OAJ07032.1 - 0.17 11.7 0.1 1.5 8.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ07032.1 - 1.8 8.3 7.5 0.067 12.9 0.3 2.3 3 0 0 3 3 2 0 Part of AAA domain DUF2611 PF11022.3 OAJ07033.1 - 1.4e-13 50.6 1.8 1.1e-12 47.8 1.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) DUF533 PF04391.7 OAJ07033.1 - 0.088 12.1 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Cyt-b5 PF00173.23 OAJ07034.1 - 1.3e-18 66.5 0.0 1.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF605 PF04652.11 OAJ07034.1 - 0.21 10.9 10.1 0.25 10.7 7.0 1.1 1 0 0 1 1 1 0 Vta1 like Bac_surface_Ag PF01103.18 OAJ07035.1 - 1.8e-31 109.7 1.4 3.1e-31 109.0 1.0 1.3 1 1 0 1 1 1 1 Surface antigen dCMP_cyt_deam_1 PF00383.17 OAJ07036.1 - 3.8e-12 45.7 0.3 6e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 OAJ07036.1 - 5.9e-09 35.8 0.2 7.4e-09 35.4 0.2 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 OAJ07036.1 - 0.075 12.7 0.2 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase PAP2 PF01569.16 OAJ07037.1 - 9.8e-15 54.3 2.6 1.8e-14 53.4 1.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF4203 PF13886.1 OAJ07037.1 - 0.055 12.9 1.6 0.092 12.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) UbiA PF01040.13 OAJ07037.1 - 0.21 10.7 7.0 0.13 11.5 0.6 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family Velvet PF11754.3 OAJ07038.1 - 1.2e-45 155.6 0.3 2e-44 151.6 0.2 2.5 1 1 0 1 1 1 1 Velvet factor ENTH PF01417.15 OAJ07039.1 - 4.2e-48 162.3 0.1 9e-48 161.2 0.0 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 OAJ07039.1 - 0.00088 18.0 1.1 0.00088 18.0 0.8 2.0 2 1 0 2 2 2 1 ANTH domain UIM PF02809.15 OAJ07039.1 - 0.005 16.3 9.1 0.05 13.1 0.7 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif SOBP PF15279.1 OAJ07039.1 - 0.2 12.0 19.9 0.39 11.0 13.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 OAJ07039.1 - 0.61 8.2 57.3 0.9 7.6 39.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4192 PF13830.1 OAJ07039.1 - 1.7 8.1 10.3 3 7.4 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) LSM PF01423.17 OAJ07040.1 - 1.2e-17 63.1 0.1 1.4e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 OAJ07040.1 - 1.3e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-O PF09496.5 OAJ07041.1 - 0.045 13.9 1.3 0.67 10.2 0.0 2.7 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component Porin_3 PF01459.17 OAJ07042.1 - 3.9e-58 196.9 0.1 4.8e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin EF-hand_1 PF00036.27 OAJ07043.1 - 7.2e-27 90.6 15.3 2e-08 32.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ07043.1 - 9.2e-24 83.3 11.0 8.7e-13 48.2 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ07043.1 - 2.7e-23 79.6 12.5 1.2e-07 30.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 OAJ07043.1 - 3.9e-17 61.6 14.1 3.3e-08 32.9 1.3 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 OAJ07043.1 - 3.8e-15 54.4 11.7 0.0002 20.5 0.7 4.4 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 OAJ07043.1 - 5.9e-09 35.7 0.3 0.0032 17.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ07043.1 - 3.6e-06 26.6 2.5 0.015 14.9 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 OAJ07043.1 - 0.008 15.7 0.2 0.12 11.9 0.0 2.3 2 1 1 3 3 3 1 Caleosin related protein Toprim_2 PF13155.1 OAJ07043.1 - 0.082 13.2 1.6 1.8 8.9 0.0 2.7 1 1 2 3 3 3 0 Toprim-like His_biosynth PF00977.16 OAJ07044.1 - 6.1e-41 140.1 0.1 4.3e-38 130.8 0.0 2.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 OAJ07044.1 - 8.7e-23 80.7 0.0 1.7e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 OAJ07044.1 - 4.1e-10 39.4 0.0 1.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 OAJ07044.1 - 2.7e-08 33.6 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 OAJ07044.1 - 0.074 12.4 0.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase C26 GPI-anchored PF10342.4 OAJ07045.1 - 0.01 16.3 1.2 0.042 14.3 1.0 2.0 1 1 1 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MFS_1 PF07690.11 OAJ07046.1 - 1.3e-18 66.8 13.8 1.3e-18 66.8 9.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Nop14 PF04147.7 OAJ07046.1 - 6.8 4.4 4.9 9.8 3.9 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family UQ_con PF00179.21 OAJ07047.1 - 3.8e-21 74.9 0.0 4.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AMP-binding PF00501.23 OAJ07049.1 - 1.3e-77 261.0 0.0 1.9e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 OAJ07049.1 - 6.1e-65 218.6 0.0 9.6e-65 217.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 OAJ07049.1 - 6.2e-14 52.0 0.0 1.6e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 OAJ07049.1 - 3.1e-09 37.6 0.0 8.8e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 OAJ07049.1 - 3.9e-07 29.7 0.0 9.2e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 OAJ07049.1 - 0.00077 18.3 0.0 0.058 12.2 0.0 2.4 2 0 0 2 2 2 1 Condensation domain 3Beta_HSD PF01073.14 OAJ07049.1 - 0.0008 18.1 0.0 0.051 12.2 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ07049.1 - 0.092 11.6 0.0 0.3 9.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Spc97_Spc98 PF04130.8 OAJ07050.1 - 1.5e-109 366.8 0.0 2.8e-109 365.8 0.0 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family Nop53 PF07767.6 OAJ07050.1 - 0.0019 17.2 11.4 0.0063 15.5 7.9 1.8 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF4484 PF14831.1 OAJ07050.1 - 0.036 14.1 7.3 0.28 11.2 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Apt1 PF10351.4 OAJ07050.1 - 0.13 11.0 4.6 0.26 10.1 3.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 OAJ07050.1 - 1.6 6.6 21.6 2.9 5.8 15.0 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 OAJ07050.1 - 1.6 8.2 24.4 6.1 6.3 16.9 1.9 1 0 0 1 1 1 0 YL1 nuclear protein Merozoite_SPAM PF07133.6 OAJ07050.1 - 3 7.7 18.6 3.3 7.5 11.9 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) HCO3_cotransp PF00955.16 OAJ07051.1 - 2.9e-40 138.3 14.7 3.1e-21 75.6 4.1 3.1 2 1 1 3 3 3 3 HCO3- transporter family F-box-like PF12937.2 OAJ07053.1 - 7.3e-08 32.0 0.2 1.6e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ07053.1 - 2.1e-06 27.2 0.1 2.1e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 F-box domain Nucleo_P87 PF07267.6 OAJ07053.1 - 0.15 10.6 0.2 0.3 9.7 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Fringe PF02434.11 OAJ07054.1 - 0.62 9.2 2.5 12 4.9 1.8 2.2 1 1 0 1 1 1 0 Fringe-like DUF4407 PF14362.1 OAJ07055.1 - 1.6 7.5 10.0 2.8 6.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IU_nuc_hydro PF01156.14 OAJ07056.1 - 2e-93 313.0 0.0 2.3e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4407 PF14362.1 OAJ07057.1 - 1.2 7.9 8.7 2.7 6.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GRP PF07172.6 OAJ07059.1 - 0.02 15.3 28.8 0.077 13.4 4.7 2.5 2 0 0 2 2 2 0 Glycine rich protein family DAD PF02109.11 OAJ07060.1 - 2.4e-45 153.2 3.6 3.2e-45 152.7 2.5 1.2 1 0 0 1 1 1 1 DAD family Mucin PF01456.12 OAJ07060.1 - 0.019 14.7 14.5 0.029 14.1 10.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2061 PF09834.4 OAJ07060.1 - 0.13 12.5 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2061) DUF2207 PF09972.4 OAJ07060.1 - 0.14 10.6 0.1 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.1 OAJ07060.1 - 0.23 11.1 4.1 0.32 10.6 2.8 1.3 1 0 0 1 1 1 0 TMEM154 protein family SOG2 PF10428.4 OAJ07060.1 - 0.3 9.6 9.5 0.37 9.4 6.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Adeno_PIX PF03955.9 OAJ07060.1 - 0.32 11.5 4.0 0.52 10.8 2.8 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) DUF4617 PF15395.1 OAJ07060.1 - 2.7 5.9 6.7 3.1 5.7 4.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4617) Pex24p PF06398.6 OAJ07061.1 - 3.9e-06 25.9 0.6 6.4e-06 25.2 0.4 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Adeno_PV PF03910.8 OAJ07061.1 - 0.076 12.0 7.3 0.15 11.0 5.0 1.4 1 0 0 1 1 1 0 Adenovirus minor core protein PV PRCC PF10253.4 OAJ07062.1 - 7e-09 36.6 18.0 7e-09 36.6 12.5 2.1 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF822 PF05687.8 OAJ07062.1 - 0.024 15.0 1.7 0.024 15.0 1.1 3.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF822) DSPc PF00782.15 OAJ07063.1 - 0.00049 19.6 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 OAJ07063.1 - 0.0011 19.2 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 OAJ07063.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 OAJ07063.1 - 0.035 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Asp PF00026.18 OAJ07064.1 - 8.8e-61 205.8 0.6 1.2e-60 205.4 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 OAJ07064.1 - 6.7e-10 39.1 0.2 4.3e-09 36.5 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 OAJ07064.1 - 0.084 12.4 0.0 0.3 10.6 0.0 1.9 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal OTOS PF15182.1 OAJ07064.1 - 2.8 7.6 8.9 0.13 11.9 0.7 2.6 3 0 0 3 3 3 0 Otospiralin MFS_1 PF07690.11 OAJ07065.1 - 9e-17 60.8 44.1 5.4e-16 58.2 10.1 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Daxx PF03344.10 OAJ07072.1 - 0.0052 15.3 37.9 0.0075 14.8 26.1 1.3 1 1 0 1 1 1 1 Daxx Family Nop14 PF04147.7 OAJ07072.1 - 0.36 8.6 40.9 0.0075 14.2 22.9 1.8 2 0 0 2 2 2 0 Nop14-like family DUF2890 PF11081.3 OAJ07072.1 - 2.4 8.2 21.5 11 6.0 12.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 OAJ07072.1 - 3.2 5.7 19.8 5.8 4.8 13.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 OAJ07072.1 - 7.9 4.3 28.0 0.12 10.3 14.4 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF1688 PF07958.6 OAJ07074.1 - 1.2e-144 481.9 0.0 1.1e-142 475.5 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) Asp_protease PF09668.5 OAJ07075.1 - 4.8e-60 200.5 0.0 7.3e-60 199.9 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 OAJ07075.1 - 1.2e-09 38.5 0.0 2.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 OAJ07075.1 - 3.8e-08 32.6 0.0 7.6e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 OAJ07075.1 - 5.6e-07 29.2 0.0 1.6e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 OAJ07075.1 - 0.00029 20.7 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 OAJ07075.1 - 0.00035 20.4 0.0 0.00088 19.1 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease XPC-binding PF09280.6 OAJ07075.1 - 0.00039 19.8 0.5 0.00094 18.5 0.4 1.6 1 0 0 1 1 1 1 XPC-binding domain Ubiquitin_2 PF14560.1 OAJ07075.1 - 0.0024 18.1 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 OAJ07075.1 - 0.0049 16.5 0.1 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pribosyltran_N PF13793.1 OAJ07076.1 - 6.6e-44 148.3 0.1 6.6e-43 145.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 OAJ07076.1 - 2.8e-39 134.7 2.5 6.2e-32 110.8 0.1 2.8 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 OAJ07076.1 - 9.6e-12 44.7 2.4 6.4e-11 42.0 0.4 2.9 3 1 1 4 4 4 1 Phosphoribosyl transferase domain UPRTase PF14681.1 OAJ07076.1 - 0.064 12.4 0.1 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Peptidase_S10 PF00450.17 OAJ07077.1 - 8e-113 377.7 1.0 1.1e-112 377.3 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ07077.1 - 9.3e-06 25.6 0.0 0.00016 21.6 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family TpcC PF12642.2 OAJ07077.1 - 0.018 14.5 0.1 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Phasin PF05597.6 OAJ07077.1 - 0.089 12.5 1.0 0.16 11.6 0.7 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF883 PF05957.8 OAJ07077.1 - 0.17 12.2 1.0 0.38 11.1 0.7 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) NDUFA12 PF05071.11 OAJ07078.1 - 2.6e-24 85.6 0.1 3.4e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTH2 PF01981.11 OAJ07079.1 - 4.7e-47 158.4 0.8 6.2e-47 158.0 0.6 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PTH2 PF01981.11 OAJ07080.1 - 3.6e-05 23.4 0.0 6.8e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF1077 PF06417.7 OAJ07081.1 - 5e-48 161.5 0.6 6.7e-48 161.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Acyl-CoA_dh_1 PF00441.19 OAJ07082.1 - 4.5e-46 156.6 4.8 4.5e-46 156.6 3.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 OAJ07082.1 - 1.2e-26 93.5 0.3 3.2e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ07082.1 - 7.4e-22 78.0 2.8 7.4e-22 78.0 2.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ07082.1 - 5e-17 61.1 0.0 9.5e-17 60.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3011 PF11218.3 OAJ07082.1 - 0.06 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) Elong_Iki1 PF10483.4 OAJ07083.1 - 4.3e-12 45.9 0.0 3e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Elongator subunit Iki1 Acyl-CoA_dh_N PF02771.11 OAJ07084.1 - 1.3e-27 96.6 0.1 3.3e-27 95.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 OAJ07084.1 - 4.7e-24 85.1 0.0 1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ07084.1 - 2.8e-18 65.1 1.2 3.6e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 OAJ07084.1 - 5.9e-06 26.5 0.1 5.9e-06 26.5 0.1 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain DDE_3 PF13358.1 OAJ07085.1 - 1.3e-29 102.7 0.0 1.9e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 OAJ07085.1 - 0.00019 21.5 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix rve PF00665.21 OAJ07085.1 - 0.0003 20.8 0.0 0.00066 19.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_7 PF02796.10 OAJ07085.1 - 0.12 12.3 0.7 0.66 9.8 0.0 2.6 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase DUF1115 PF06544.7 OAJ07086.1 - 5.3e-07 29.3 0.0 6.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF2638 PF10937.3 OAJ07086.1 - 0.019 15.9 0.0 0.028 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) Rhodanese PF00581.15 OAJ07087.1 - 0.055 13.8 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain Retrotrans_gag PF03732.12 OAJ07088.1 - 2.2e-13 50.0 1.2 2.2e-13 50.0 0.8 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 OAJ07088.1 - 0.057 13.3 3.2 0.092 12.7 2.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Glyco_tranf_2_3 PF13641.1 OAJ07089.1 - 2.6e-25 89.5 0.0 3.6e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 OAJ07089.1 - 1.7e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 OAJ07089.1 - 2.8e-09 36.4 0.1 9.4e-09 34.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 OAJ07089.1 - 3.9e-07 29.9 5.0 7e-07 29.1 3.4 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 OAJ07089.1 - 0.00072 18.0 0.8 0.0035 15.7 0.6 1.8 1 1 0 1 1 1 1 Chitin synthase M20_dimer PF07687.9 OAJ07090.1 - 1.9e-09 37.2 0.1 4.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 OAJ07090.1 - 4.2e-08 32.9 0.2 6.1e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 NKWYS PF10364.4 OAJ07090.1 - 0.087 12.5 0.3 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein EBP50_C-term PF09007.6 OAJ07091.1 - 0.28 11.0 3.0 0.51 10.2 2.1 1.4 1 0 0 1 1 1 0 EBP50, C-terminal MSP1_C PF07462.6 OAJ07091.1 - 4.8 5.4 6.2 5.2 5.3 4.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CH PF00307.26 OAJ07092.1 - 7.3e-40 135.3 0.1 7.5e-22 77.4 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 OAJ07092.1 - 6.1e-18 64.5 0.0 2.9e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 OAJ07092.1 - 2.1e-13 49.7 0.1 5.6e-10 38.7 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain Med21 PF11221.3 OAJ07092.1 - 0.012 15.5 0.3 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Subunit 21 of Mediator complex EF-hand_6 PF13405.1 OAJ07092.1 - 0.039 13.8 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain PspA_IM30 PF04012.7 OAJ07092.1 - 0.059 12.7 4.3 0.12 11.7 3.0 1.5 1 0 0 1 1 1 0 PspA/IM30 family CENP-F_leu_zip PF10473.4 OAJ07092.1 - 0.082 12.7 2.6 0.18 11.6 1.8 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4061 PF13270.1 OAJ07092.1 - 0.087 12.9 0.8 0.29 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Baculo_PEP_C PF04513.7 OAJ07092.1 - 0.25 11.1 4.7 0.11 12.3 0.6 2.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.16 OAJ07092.1 - 0.29 11.4 5.0 0.41 10.9 0.5 2.9 1 1 0 2 2 2 0 Spectrin repeat SlyX PF04102.7 OAJ07092.1 - 0.97 9.8 4.2 9 6.7 0.7 2.7 1 1 1 2 2 2 0 SlyX CAS_CSE1 PF03378.10 OAJ07093.1 - 2.3e-122 408.4 0.0 8.2e-122 406.6 0.0 1.8 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 OAJ07093.1 - 1.2e-120 402.4 0.0 2.1e-120 401.6 0.0 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 OAJ07093.1 - 4.4e-10 39.3 1.3 7e-08 32.2 0.3 4.0 3 1 0 3 3 3 1 Importin-beta N-terminal domain DUF1840 PF08895.6 OAJ07093.1 - 0.03 14.3 0.1 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) HEAT PF02985.17 OAJ07093.1 - 0.057 13.5 5.3 2.9 8.1 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Xpo1 PF08389.7 OAJ07093.1 - 0.067 13.0 0.0 0.35 10.7 0.0 2.3 1 0 0 1 1 1 0 Exportin 1-like protein DUF2315 PF10231.4 OAJ07095.1 - 4.5e-13 49.1 0.2 6.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) DDE_1 PF03184.14 OAJ07096.1 - 3.8e-33 114.4 0.0 6.3e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4351 PF14261.1 OAJ07096.1 - 0.023 14.5 0.1 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) F-box-like PF12937.2 OAJ07097.1 - 1.3e-10 40.8 0.1 1.3e-10 40.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ07097.1 - 5e-06 26.0 1.5 1.7e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 OAJ07097.1 - 0.0026 17.2 0.1 0.096 12.1 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 OAJ07097.1 - 0.087 12.3 0.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat zf-Mss51 PF13824.1 OAJ07098.1 - 4.1e-21 74.5 2.0 9.6e-21 73.3 1.4 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.13 OAJ07099.1 - 5.1e-154 512.3 14.0 7.4e-154 511.8 9.7 1.2 1 0 0 1 1 1 1 Calreticulin family TRAM_LAG1_CLN8 PF03798.11 OAJ07099.1 - 3.6e-05 23.4 12.2 6.2e-05 22.6 8.4 1.3 1 0 0 1 1 1 1 TLC domain DUF1282 PF06930.7 OAJ07099.1 - 0.16 11.5 5.4 0.32 10.6 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4501 PF14946.1 OAJ07100.1 - 0.002 17.6 0.1 0.0023 17.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4501) rve PF00665.21 OAJ07101.1 - 1.7e-05 24.9 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain CPSase_L_D3 PF02787.14 OAJ07101.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PHD PF00628.24 OAJ07102.1 - 5.9e-06 25.8 7.9 5.9e-06 25.8 5.5 1.9 2 0 0 2 2 2 1 PHD-finger CPSase_L_D3 PF02787.14 OAJ07104.1 - 0.00025 20.7 0.0 0.00073 19.3 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain HTH_23 PF13384.1 OAJ07104.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Lectin_leg-like PF03388.8 OAJ07105.1 - 3.8e-59 199.6 0.0 5e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 OAJ07105.1 - 0.1 11.9 0.0 6.9 5.9 0.0 2.6 2 1 0 2 2 2 0 Legume lectin domain Nup160 PF11715.3 OAJ07106.1 - 1.3e-16 59.8 0.3 1.7e-12 46.2 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Apc3 PF12895.2 OAJ07106.1 - 0.03 14.4 0.8 0.095 12.8 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4486 PF14858.1 OAJ07106.1 - 1.3 7.1 0.1 2.1 6.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) NmrA PF05368.8 OAJ07107.1 - 9.9e-38 129.6 0.1 1.2e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 OAJ07107.1 - 8.4e-14 51.9 0.1 1.3e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ07107.1 - 9.1e-05 21.2 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 OAJ07107.1 - 0.0018 17.9 0.1 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 OAJ07107.1 - 0.0018 18.2 0.1 0.0028 17.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RPA_C PF08784.6 OAJ07108.1 - 7.2e-11 42.4 2.1 1.1e-10 41.7 0.1 2.2 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 OAJ07108.1 - 2.4e-09 36.9 0.1 4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_20 PF12840.2 OAJ07108.1 - 0.0029 17.3 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain BOF PF04076.8 OAJ07108.1 - 0.055 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein DOMON PF03351.12 OAJ07108.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 DOMON domain zf-C2HC_2 PF13913.1 OAJ07109.1 - 0.95 9.2 6.7 0.085 12.5 0.9 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FA_hydroxylase PF04116.8 OAJ07110.1 - 7.3e-11 42.4 9.8 7.3e-11 42.4 6.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RVT_1 PF00078.22 OAJ07111.1 - 0.098 12.0 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Dimer_Tnp_hAT PF05699.9 OAJ07112.1 - 3e-06 26.7 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region 3-alpha PF03475.9 OAJ07112.1 - 0.013 15.2 0.3 0.039 13.6 0.2 1.8 1 0 0 1 1 1 0 3-alpha domain GFO_IDH_MocA PF01408.17 OAJ07114.1 - 7.7e-19 68.3 0.1 1.2e-18 67.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Iso_dh PF00180.15 OAJ07115.1 - 5.1e-77 259.1 0.0 6.5e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhageMin_Tail PF10145.4 OAJ07115.1 - 0.076 12.6 2.6 6 6.4 0.1 2.4 2 0 0 2 2 2 0 Phage-related minor tail protein Ribonuclease_T2 PF00445.13 OAJ07116.1 - 1.9e-41 141.7 0.1 2.6e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family MFS_1 PF07690.11 OAJ07117.1 - 2.4e-42 144.9 23.3 1.8e-37 128.9 12.8 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 OAJ07117.1 - 3.3e-05 22.7 0.1 4.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 BT1 family MFS_2 PF13347.1 OAJ07117.1 - 0.0025 16.2 9.8 0.0025 16.2 6.8 3.2 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 OAJ07117.1 - 0.0045 16.7 2.5 0.6 9.9 0.0 3.7 3 1 0 3 3 3 1 MFS_1 like family Oxysterol_BP PF01237.13 OAJ07118.1 - 1.4e-51 175.0 0.0 7.9e-41 139.7 0.1 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein COesterase PF00135.23 OAJ07119.1 - 3e-82 277.0 0.6 1.1e-73 248.8 0.4 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ07119.1 - 5.7e-07 29.3 0.0 2.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_Mycoplasma PF07672.8 OAJ07119.1 - 0.029 13.5 0.2 0.049 12.7 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter RasGAP PF00616.14 OAJ07121.1 - 3.6e-22 78.9 0.0 3e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 OAJ07121.1 - 0.00048 19.9 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain HsbA PF12296.3 OAJ07122.1 - 3.3e-13 49.5 11.2 4.4e-13 49.1 7.8 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.8 OAJ07122.1 - 0.095 12.3 1.1 0.12 12.0 0.8 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ FUN14 PF04930.10 OAJ07122.1 - 0.22 11.8 2.8 1.1 9.5 2.0 2.2 1 1 0 1 1 1 0 FUN14 family RVT_1 PF00078.22 OAJ07123.1 - 3.7e-22 78.7 0.0 8.9e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07123.1 - 5.5e-10 39.3 0.0 1.4e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.6 OAJ07123.1 - 1.6e-08 34.6 0.0 4.7e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Chromo PF00385.19 OAJ07123.1 - 6.2e-07 28.9 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 OAJ07123.1 - 0.041 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 OAJ07123.1 - 0.19 12.2 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4175 PF13779.1 OAJ07125.1 - 7.7 4.0 9.1 8.5 3.9 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PX PF00787.19 OAJ07126.1 - 5.2e-21 74.5 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 OAJ07126.1 - 8.4e-08 31.7 1.9 0.0032 16.7 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like FAM92 PF06730.6 OAJ07126.1 - 0.00064 19.1 0.7 0.0012 18.2 0.5 1.3 1 0 0 1 1 1 1 FAM92 protein BAR PF03114.13 OAJ07126.1 - 0.096 12.1 1.5 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 BAR domain AAA_2 PF07724.9 OAJ07130.1 - 2.2e-43 148.1 0.0 2e-39 135.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 OAJ07130.1 - 7.5e-25 86.6 0.5 2.9e-24 84.7 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 OAJ07130.1 - 7.8e-19 68.1 0.0 1.6e-09 38.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ07130.1 - 1.8e-12 47.0 0.2 6.6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ07130.1 - 4.9e-11 42.5 0.0 2.8e-06 27.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 OAJ07130.1 - 2.1e-10 40.8 10.9 0.00095 19.1 0.0 5.1 3 3 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 OAJ07130.1 - 2e-07 31.2 1.4 0.0063 16.6 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 OAJ07130.1 - 8.6e-06 25.4 0.0 0.099 12.4 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 OAJ07130.1 - 2.7e-05 23.3 0.0 0.0042 16.2 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 OAJ07130.1 - 5.9e-05 22.8 1.0 0.02 14.5 0.3 3.4 2 1 0 2 2 2 1 Archaeal ATPase TrwB_AAD_bind PF10412.4 OAJ07130.1 - 6.3e-05 21.7 0.0 0.041 12.5 0.0 2.6 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_14 PF13173.1 OAJ07130.1 - 9.4e-05 22.3 0.0 0.026 14.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 OAJ07130.1 - 0.00016 20.9 0.2 0.13 11.3 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 OAJ07130.1 - 0.00017 22.3 1.6 0.12 13.1 0.0 3.5 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 OAJ07130.1 - 0.00027 19.8 0.1 0.017 13.8 0.0 2.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_30 PF13604.1 OAJ07130.1 - 0.00034 20.2 0.0 0.41 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ07130.1 - 0.00045 20.5 0.0 1.9 8.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 OAJ07130.1 - 0.00085 19.0 0.2 0.61 9.7 0.0 2.9 3 0 0 3 3 2 1 NACHT domain IstB_IS21 PF01695.12 OAJ07130.1 - 0.00091 18.6 0.0 0.63 9.4 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ07130.1 - 0.0011 19.0 0.3 1.5 8.9 0.0 3.2 4 0 0 4 4 2 1 RNA helicase AAA_28 PF13521.1 OAJ07130.1 - 0.0023 17.8 2.7 3.9 7.3 0.0 3.9 4 1 0 4 4 4 1 AAA domain SRP54 PF00448.17 OAJ07130.1 - 0.0027 17.1 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_3 PF07726.6 OAJ07130.1 - 0.0079 15.8 0.0 0.19 11.3 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 OAJ07130.1 - 0.0084 15.8 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 OAJ07130.1 - 0.0087 15.9 0.0 3.4 7.5 0.0 3.3 2 0 0 2 2 2 1 AAA domain CENP-F_leu_zip PF10473.4 OAJ07130.1 - 0.011 15.6 10.2 0.025 14.4 7.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ResIII PF04851.10 OAJ07130.1 - 0.012 15.4 0.5 4.1 7.1 0.0 3.6 4 1 1 5 5 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 OAJ07130.1 - 0.016 14.1 0.3 0.56 9.1 0.0 2.8 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 OAJ07130.1 - 0.025 13.4 0.4 6.3 5.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) DUF258 PF03193.11 OAJ07130.1 - 0.037 13.2 0.0 0.91 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 OAJ07130.1 - 0.039 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 1 0 Torsin Miro PF08477.8 OAJ07130.1 - 0.043 14.3 0.0 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 OAJ07130.1 - 0.13 11.7 0.2 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 OAJ07130.1 - 0.15 11.7 0.0 17 5.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 UvrD-helicase PF00580.16 OAJ07130.1 - 0.19 11.0 0.1 0.19 11.0 0.0 3.3 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain DUF87 PF01935.12 OAJ07130.1 - 2.7 7.7 5.6 14 5.4 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 Profilin PF00235.14 OAJ07131.1 - 3.5e-40 136.8 0.0 3.9e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Profilin DASH_Dad2 PF08654.5 OAJ07132.1 - 2.6e-21 75.5 0.0 6e-21 74.3 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 RabGAP-TBC PF00566.13 OAJ07133.1 - 1.2e-43 149.0 0.0 1.7e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PEMT PF04191.8 OAJ07134.1 - 1.9e-33 114.7 8.0 2.4e-33 114.4 4.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase EI24 PF07264.6 OAJ07134.1 - 0.00027 20.4 4.5 0.0056 16.1 3.1 2.1 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF3123 PF11321.3 OAJ07134.1 - 0.1 12.8 1.0 0.15 12.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF4345 PF14248.1 OAJ07134.1 - 0.69 9.3 6.3 0.12 11.8 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4345) Vps5 PF09325.5 OAJ07135.1 - 5e-59 199.4 4.1 5e-59 199.4 2.8 2.8 2 1 1 3 3 3 1 Vps5 C terminal like RmlD_sub_bind PF04321.12 OAJ07135.1 - 1.1e-47 162.3 1.2 1.2e-47 162.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.16 OAJ07135.1 - 9.2e-23 80.8 0.0 3.9e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PX PF00787.19 OAJ07135.1 - 7.8e-22 77.2 0.0 7.8e-22 77.2 0.0 2.1 3 0 0 3 3 3 1 PX domain NAD_binding_10 PF13460.1 OAJ07135.1 - 4.4e-10 39.8 0.1 1.3e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 OAJ07135.1 - 1.3e-08 34.0 0.0 8.7e-07 28.1 0.0 2.7 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 OAJ07135.1 - 8e-06 24.9 0.0 0.00032 19.7 0.0 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein MIP-T3 PF10243.4 OAJ07135.1 - 0.0018 16.8 58.2 0.0018 16.8 40.4 2.3 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Peptidase_S10 PF00450.17 OAJ07136.1 - 1.2e-71 242.0 0.1 1.5e-71 241.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 OAJ07136.1 - 0.038 13.8 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_5 PF07994.7 OAJ07137.1 - 1.1e-109 366.5 0.0 1.4e-109 366.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 OAJ07137.1 - 1e-42 144.4 0.2 2.4e-42 143.2 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase zf-U1 PF06220.7 OAJ07138.1 - 9.7e-06 25.0 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 U1 zinc finger PALP PF00291.20 OAJ07139.1 - 2e-58 198.0 0.1 1.2e-56 192.2 0.1 2.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BTB PF00651.26 OAJ07139.1 - 2.5e-11 43.5 0.0 4.1e-05 23.5 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain 2OG-FeII_Oxy_3 PF13640.1 OAJ07140.1 - 9.8e-10 38.8 0.0 1.6e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 OAJ07140.1 - 0.0001 21.8 0.1 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ07140.1 - 0.007 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HAT PF02184.11 OAJ07143.1 - 2.1e-17 62.5 52.5 2.4e-09 36.7 0.4 13.6 15 0 0 15 15 14 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 OAJ07143.1 - 1.6e-15 56.1 28.6 0.0085 16.6 0.0 12.1 7 3 8 15 15 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ07143.1 - 2e-09 37.6 1.2 0.84 10.0 0.0 6.5 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ07143.1 - 2.7e-06 26.9 7.2 0.38 10.4 0.0 6.3 5 2 2 7 7 7 2 TPR repeat TPR_7 PF13176.1 OAJ07143.1 - 7.3e-05 22.2 4.3 11 6.0 0.1 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ07143.1 - 8.1e-05 23.1 19.9 0.0055 17.3 0.0 7.3 4 3 5 10 10 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ07143.1 - 0.00032 20.5 11.6 1 9.3 0.1 6.2 5 2 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ07143.1 - 0.00034 20.2 11.1 27 4.9 0.0 8.1 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ07143.1 - 0.0085 15.8 0.0 14 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ07143.1 - 0.025 14.7 0.2 4.8 7.6 0.0 4.0 2 0 0 2 2 2 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 OAJ07143.1 - 0.21 11.3 14.0 0.13 12.0 0.3 4.9 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 Nucleoplasmin PF03066.10 OAJ07143.1 - 1.6 8.2 16.1 0.34 10.4 2.5 2.8 3 0 0 3 3 3 0 Nucleoplasmin Copper-fist PF00649.13 OAJ07144.1 - 2.2e-14 52.3 0.4 6.2e-14 50.9 0.3 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain COesterase PF00135.23 OAJ07145.1 - 7.5e-81 272.4 3.9 1.5e-73 248.3 1.7 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ07145.1 - 6.7e-07 29.0 0.0 1.7e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07145.1 - 0.0028 17.4 0.2 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ07145.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3405 PF11885.3 OAJ07150.1 - 9.9e-137 456.1 1.4 3.1e-128 428.1 1.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3405) Pex14_N PF04695.8 OAJ07150.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_S11 PF00411.14 OAJ07151.1 - 8.2e-11 42.0 0.3 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein S11 VirB3 PF05101.8 OAJ07152.1 - 0.026 14.4 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF3481 PF11980.3 OAJ07152.1 - 0.096 12.5 1.2 0.12 12.2 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) SseC PF04888.7 OAJ07152.1 - 3.5 6.8 7.2 3.9 6.7 5.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family MT-A70 PF05063.9 OAJ07153.1 - 9.5e-36 122.9 2.0 1.6e-31 109.1 0.1 4.1 2 1 0 2 2 2 2 MT-A70 DUF947 PF06102.7 OAJ07155.1 - 4.5e-28 98.1 19.7 4.5e-28 98.1 13.7 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF947) FlxA PF14282.1 OAJ07155.1 - 0.0041 17.0 0.8 0.0041 17.0 0.6 3.3 4 0 0 4 4 4 1 FlxA-like protein Sugar_tr PF00083.19 OAJ07157.1 - 5.1e-103 345.0 16.2 6.1e-103 344.8 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ07157.1 - 9.4e-28 96.9 22.5 9.4e-28 96.9 15.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 OAJ07157.1 - 1.1e-05 24.0 17.8 0.0021 16.5 2.0 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3180 PF11377.3 OAJ07157.1 - 0.027 14.3 3.2 0.064 13.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) AAA PF00004.24 OAJ07158.1 - 1.3e-48 164.5 0.0 2.3e-43 147.5 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 OAJ07158.1 - 8.9e-20 70.5 0.1 2.2e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 OAJ07158.1 - 3.3e-08 34.3 0.0 0.013 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 OAJ07158.1 - 1.8e-07 31.3 0.2 0.059 13.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 OAJ07158.1 - 3.4e-07 30.4 11.8 0.012 15.6 3.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 OAJ07158.1 - 5.6e-06 26.0 0.9 0.011 15.4 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 OAJ07158.1 - 1.1e-05 25.7 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 OAJ07158.1 - 5.4e-05 22.9 0.1 0.41 10.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 OAJ07158.1 - 0.00012 21.9 0.0 0.067 13.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 OAJ07158.1 - 0.00016 21.1 1.5 1.1 8.6 0.0 4.0 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.7 OAJ07158.1 - 0.0004 19.5 0.0 0.003 16.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 OAJ07158.1 - 0.00041 20.0 1.0 4.2 7.0 0.0 4.5 4 0 0 4 4 4 1 NACHT domain AAA_28 PF13521.1 OAJ07158.1 - 0.0011 18.9 0.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 OAJ07158.1 - 0.0012 17.5 0.2 0.14 10.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 OAJ07158.1 - 0.0014 18.0 0.1 0.94 8.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 OAJ07158.1 - 0.0015 18.6 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 OAJ07158.1 - 0.0016 17.6 0.2 0.85 8.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 OAJ07158.1 - 0.0025 16.9 0.3 1 8.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.4 OAJ07158.1 - 0.0029 16.6 0.0 0.94 8.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 OAJ07158.1 - 0.0073 16.2 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ07158.1 - 0.0075 16.1 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.13 OAJ07158.1 - 0.0092 15.5 0.0 0.053 13.0 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 OAJ07158.1 - 0.033 13.8 0.1 0.58 9.7 0.0 2.7 2 1 1 3 3 3 0 Adenylylsulphate kinase SKI PF01202.17 OAJ07158.1 - 0.039 13.8 0.2 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase KaiC PF06745.8 OAJ07158.1 - 0.069 12.2 0.2 10 5.1 0.1 2.3 2 0 0 2 2 2 0 KaiC Cytidylate_kin2 PF13189.1 OAJ07158.1 - 0.093 12.6 0.7 0.59 10.0 0.0 2.5 3 0 0 3 3 3 0 Cytidylate kinase-like family UPF0079 PF02367.12 OAJ07158.1 - 0.11 12.1 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 OAJ07158.1 - 0.11 11.9 0.0 8.4 5.8 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain G-alpha PF00503.15 OAJ07158.1 - 0.16 10.6 2.8 0.3 9.7 1.9 1.5 1 0 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.17 OAJ07158.1 - 0.24 10.2 0.1 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Jacalin PF01419.12 OAJ07160.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 2.0 1 1 0 1 1 1 1 Jacalin-like lectin domain Cullin_binding PF03556.10 OAJ07162.1 - 0.071 13.2 0.3 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Cullin binding F-box PF00646.28 OAJ07164.1 - 5.9e-07 28.9 0.3 1.2e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ07164.1 - 0.0086 15.7 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 OAJ07165.1 - 5.6e-09 35.5 3.8 0.0013 18.4 0.1 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 OAJ07165.1 - 0.07 12.8 6.9 1.1 8.9 0.0 3.9 4 0 0 4 4 4 0 F-box domain Vezatin PF12632.2 OAJ07166.1 - 0.00042 19.4 0.0 0.001 18.1 0.0 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Aldo_ket_red PF00248.16 OAJ07167.1 - 1e-77 260.7 0.0 1.1e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FF PF01846.14 OAJ07168.1 - 2.6e-22 78.5 5.0 2e-10 40.4 0.0 5.1 5 1 0 5 5 5 2 FF domain WW PF00397.21 OAJ07168.1 - 1.4e-13 50.3 11.9 1.7e-06 27.7 1.5 2.7 2 0 0 2 2 2 2 WW domain Rdx PF10262.4 OAJ07169.1 - 3e-20 72.0 0.0 8.2e-20 70.6 0.0 1.7 1 1 0 1 1 1 1 Rdx family DDE_3 PF13358.1 OAJ07171.1 - 1.8e-31 108.8 0.0 2.8e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 OAJ07171.1 - 1.2e-05 24.5 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 OAJ07171.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 OAJ07171.1 - 0.0028 18.4 0.0 0.11 13.3 0.0 2.9 3 1 0 3 3 3 1 Homeodomain-like domain Arg_repressor PF01316.16 OAJ07171.1 - 0.028 13.9 0.2 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain rve PF00665.21 OAJ07171.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain PIF1 PF05970.9 OAJ07174.1 - 1.5e-23 83.3 0.0 3e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 OAJ07174.1 - 2.7e-12 46.6 0.0 1.2e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ07174.1 - 3.7e-07 29.7 0.2 1.5e-06 27.8 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain Helitron_like_N PF14214.1 OAJ07174.1 - 5.4e-06 26.2 0.0 1.9e-05 24.5 0.0 2.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 OAJ07174.1 - 0.0055 16.7 0.0 0.031 14.2 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 OAJ07174.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 OAJ07174.1 - 0.087 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 OAJ07174.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin DDE_Tnp_4 PF13359.1 OAJ07176.1 - 8.8e-15 54.6 0.2 2.3e-14 53.3 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease Peptidase_S49_N PF08496.5 OAJ07176.1 - 8.5 6.1 9.7 0.74 9.5 0.3 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal ELMO_CED12 PF04727.8 OAJ07179.1 - 4.1e-32 111.0 0.0 6.5e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 OAJ07179.1 - 4.8e-09 36.1 0.0 6.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.9 OAJ07179.1 - 0.0042 16.2 0.0 0.012 14.7 0.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H Drf_FH3 PF06367.11 OAJ07179.1 - 0.008 15.5 0.1 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain WSN PF02206.13 OAJ07179.1 - 0.011 15.5 0.0 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function PHF5 PF03660.9 OAJ07180.1 - 6.2e-44 148.4 8.8 6.7e-44 148.3 6.1 1.0 1 0 0 1 1 1 1 PHF5-like protein UPF0547 PF10571.4 OAJ07180.1 - 0.052 13.2 2.1 0.052 13.2 1.5 3.3 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 DZR PF12773.2 OAJ07180.1 - 0.44 10.4 14.2 0.17 11.7 5.7 2.7 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 OAJ07180.1 - 0.44 10.3 11.4 2.8 7.7 0.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 OAJ07180.1 - 0.74 9.5 11.5 0.036 13.7 2.7 2.3 1 1 1 2 2 2 0 PHD-finger DER1 PF04511.10 OAJ07181.1 - 4.2e-06 26.4 3.0 5.9e-06 25.9 2.1 1.3 1 1 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 OAJ07181.1 - 1.1e-05 25.4 1.4 2.3e-05 24.4 1.0 1.8 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 OAJ07181.1 - 3e-05 24.2 0.7 5.7e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) AtpR PF12966.2 OAJ07181.1 - 2.6 8.2 8.2 7.3 6.8 2.1 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit RNase_PH PF01138.16 OAJ07182.1 - 2.8e-16 60.0 0.0 6.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 OAJ07182.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Dynactin PF12455.3 OAJ07183.1 - 3e-51 173.9 3.8 3e-51 173.9 2.6 4.1 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 OAJ07183.1 - 3.4e-19 68.3 0.8 6.7e-19 67.3 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.1 OAJ07183.1 - 0.85 8.7 84.7 0.021 14.0 13.9 5.5 4 2 0 4 4 4 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 OAJ07185.1 - 0.021 14.7 0.2 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase End3 PF12761.2 OAJ07185.1 - 0.026 14.1 1.2 0.035 13.7 0.8 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pyr_redox_3 PF13738.1 OAJ07186.1 - 2.8e-25 89.5 0.0 3.9e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ07186.1 - 7.2e-06 26.0 0.0 2.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 OAJ07186.1 - 0.00016 20.7 0.0 0.0003 19.8 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ07186.1 - 0.00078 19.2 1.2 0.024 14.4 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 OAJ07186.1 - 0.021 13.9 0.7 0.03 13.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 OAJ07186.1 - 0.021 13.3 2.5 0.45 8.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 OAJ07186.1 - 0.051 13.6 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PRC PF05239.11 OAJ07186.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 PRC-barrel domain GIDA PF01134.17 OAJ07186.1 - 0.18 10.6 2.3 0.79 8.5 1.6 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A H_lectin PF09458.5 OAJ07187.1 - 6.8e-13 48.0 0.0 1.5e-07 30.9 0.0 2.8 2 0 0 2 2 2 2 H-type lectin domain SH3_9 PF14604.1 OAJ07188.1 - 2.1e-06 27.1 0.0 4.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 OAJ07188.1 - 8.1e-06 25.2 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ07188.1 - 1.9e-05 23.9 0.1 0.0011 18.2 0.0 2.3 1 1 0 1 1 1 1 SH3 domain Abhydrolase_6 PF12697.2 OAJ07189.1 - 1.1e-19 71.2 0.1 1.9e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ07189.1 - 3.1e-11 43.2 0.0 5.9e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 OAJ07189.1 - 2.2e-06 27.4 0.8 5e-06 26.2 0.6 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 OAJ07189.1 - 6.7e-06 25.8 0.4 9.2e-05 22.1 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 OAJ07189.1 - 0.0017 17.7 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 OAJ07189.1 - 0.15 11.4 0.1 0.44 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative esterase GrpE PF01025.14 OAJ07190.1 - 0.0051 16.3 1.1 0.0075 15.8 0.7 1.4 1 0 0 1 1 1 1 GrpE Apolipoprotein PF01442.13 OAJ07190.1 - 0.043 13.3 5.2 0.086 12.3 3.6 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1311 PF07007.7 OAJ07190.1 - 0.38 10.8 3.1 0.7 10.0 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) PIG-S PF10510.4 OAJ07191.1 - 1e-108 364.2 0.0 1.7e-108 363.5 0.0 1.3 1 1 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1789 PF08748.6 OAJ07191.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) dsDNA_bind PF01984.15 OAJ07192.1 - 4.2e-30 103.9 0.5 1.3e-28 99.1 0.6 2.0 2 0 0 2 2 2 1 Double-stranded DNA-binding domain PELOTA_1 PF15608.1 OAJ07192.1 - 0.088 12.5 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Chorion_3 PF05387.6 OAJ07192.1 - 5.6 6.3 0.0 5.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Chorion family 3 HEAT_EZ PF13513.1 OAJ07193.1 - 1.6e-27 95.2 13.6 1e-05 25.8 0.0 10.8 10 1 1 11 11 11 5 HEAT-like repeat HEAT_2 PF13646.1 OAJ07193.1 - 1.3e-22 79.9 10.8 3.2e-05 24.1 0.0 7.3 5 3 2 7 7 7 6 HEAT repeats HEAT PF02985.17 OAJ07193.1 - 1e-18 65.6 9.8 6.3e-05 22.7 0.1 8.9 8 0 0 8 8 8 5 HEAT repeat IBN_N PF03810.14 OAJ07193.1 - 2.1e-10 40.3 3.9 3e-10 39.8 0.3 3.1 3 0 0 3 3 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 OAJ07193.1 - 3.5e-07 28.9 2.2 0.036 12.4 0.0 4.4 4 0 0 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 OAJ07193.1 - 1.8e-06 28.2 0.0 0.42 11.0 0.0 5.8 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 OAJ07193.1 - 8e-06 25.3 0.0 0.79 9.0 0.0 5.6 4 2 1 5 5 5 1 CLASP N terminal UME PF08064.8 OAJ07193.1 - 9.8e-06 25.4 0.0 1.1 9.2 0.0 5.1 3 2 1 5 5 5 1 UME (NUC010) domain Cnd1 PF12717.2 OAJ07193.1 - 1.4e-05 24.9 0.1 1.8 8.3 0.0 5.1 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 OAJ07193.1 - 4.3e-05 23.4 0.0 6.4 6.8 0.0 6.3 6 1 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation CAS_CSE1 PF03378.10 OAJ07193.1 - 6.7e-05 21.3 2.2 0.12 10.6 0.0 4.5 6 0 0 6 6 6 2 CAS/CSE protein, C-terminus Cohesin_HEAT PF12765.2 OAJ07193.1 - 0.0003 20.6 0.2 0.83 9.6 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion MMS19_C PF12460.3 OAJ07193.1 - 0.019 13.6 0.4 8.4 4.9 0.0 4.7 6 1 0 6 6 6 0 RNAPII transcription regulator C-terminal DUF2237 PF09996.4 OAJ07194.1 - 4.6e-31 106.7 0.5 1.5e-30 105.0 0.4 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Cupin_1 PF00190.17 OAJ07195.1 - 2.7e-20 72.2 0.0 7.2e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 OAJ07195.1 - 5.6e-20 70.6 0.2 9.3e-16 57.0 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 OAJ07195.1 - 1e-06 28.4 0.2 0.00045 19.9 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 OAJ07195.1 - 0.00031 20.0 0.0 0.0025 17.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 OAJ07195.1 - 0.0036 16.9 0.1 1.3 8.6 0.1 2.8 1 1 1 2 2 2 2 Cupin MannoseP_isomer PF01050.13 OAJ07195.1 - 0.006 16.1 0.0 0.009 15.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_7 PF12973.2 OAJ07195.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 ChrR Cupin-like domain PemK PF02452.12 OAJ07195.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 PemK-like protein GPI PF06560.6 OAJ07195.1 - 0.094 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) 2OG-FeII_Oxy_5 PF13759.1 OAJ07195.1 - 0.1 12.9 0.0 5.6 7.3 0.0 2.5 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase CTP_transf_1 PF01148.15 OAJ07197.1 - 4e-05 23.4 4.0 4e-05 23.4 2.8 4.4 3 2 1 4 4 4 2 Cytidylyltransferase family DUF2019 PF09450.5 OAJ07198.1 - 0.04 13.7 0.1 0.047 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DUF4254 PF14063.1 OAJ07198.1 - 0.056 13.0 0.4 0.093 12.3 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) DUF465 PF04325.8 OAJ07198.1 - 0.25 11.0 2.7 0.87 9.3 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF465) F-box-like PF12937.2 OAJ07200.1 - 2.1e-05 24.1 0.2 0.00017 21.2 0.0 2.6 2 0 0 2 2 2 1 F-box-like 2OG-FeII_Oxy_3 PF13640.1 OAJ07201.1 - 0.0042 17.5 0.1 0.011 16.2 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ07201.1 - 0.0056 16.9 0.1 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2015 PF09435.5 OAJ07203.1 - 1.1e-25 89.9 0.0 1.2e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2015) UBN2 PF14223.1 OAJ07204.1 - 4.6e-10 39.3 1.1 1.1e-09 38.1 0.4 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 OAJ07204.1 - 4.3e-08 32.7 0.5 2e-07 30.5 0.1 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type HECT PF00632.20 OAJ07205.1 - 5.3e-77 259.0 0.0 7.9e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans PF04082.13 OAJ07206.1 - 1.5e-12 46.9 0.7 3.6e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ07206.1 - 1.2e-06 28.3 9.9 1.8e-06 27.7 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMN PF06003.7 OAJ07206.1 - 0.0086 15.2 1.9 0.0086 15.2 1.3 2.7 2 1 0 2 2 2 1 Survival motor neuron protein (SMN) Fungal_trans PF04082.13 OAJ07207.1 - 7.4e-12 44.6 0.7 1.3e-11 43.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ07207.1 - 2.2e-07 30.6 11.2 3.7e-07 29.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ammonium_transp PF00909.16 OAJ07208.1 - 4.9e-106 354.5 25.7 5.6e-106 354.3 17.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RVT_2 PF07727.9 OAJ07209.1 - 2.2e-83 279.0 0.0 3.1e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07209.1 - 5.1e-24 84.6 0.4 1.5e-23 83.1 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 OAJ07209.1 - 0.00041 19.9 0.0 0.00088 18.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ07209.1 - 0.0036 16.7 0.1 0.32 10.5 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.22 OAJ07209.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipl32 PF12103.3 OAJ07209.1 - 0.16 11.4 0.0 0.42 10.0 0.0 1.6 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order Kinesin PF00225.18 OAJ07210.1 - 5e-94 314.7 0.0 7.4e-94 314.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Glyco_hydro_2 PF00703.16 OAJ07213.1 - 0.014 15.8 2.9 0.084 13.3 2.0 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 DUF2413 PF10310.4 OAJ07213.1 - 0.09 11.5 7.6 0.11 11.3 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF572 PF04502.8 OAJ07213.1 - 0.89 8.7 9.0 1.2 8.3 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4614 PF15391.1 OAJ07213.1 - 2.8 7.6 9.0 5.4 6.7 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) Amidohydro_1 PF01979.15 OAJ07214.1 - 9.6e-60 202.9 0.5 1.4e-59 202.3 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 OAJ07214.1 - 2.9e-57 192.0 1.1 1.4e-56 189.8 0.4 2.4 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 OAJ07214.1 - 4e-41 139.0 0.5 9.3e-41 137.8 0.4 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 OAJ07214.1 - 3.4e-36 123.0 0.0 1.5e-35 121.0 0.0 2.0 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.6 OAJ07214.1 - 1.4e-05 24.5 0.7 3.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 OAJ07214.1 - 0.00011 21.8 2.9 0.00011 21.8 2.0 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_4 PF13147.1 OAJ07214.1 - 0.0015 18.5 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Suf PF05843.9 OAJ07215.1 - 0.35 10.5 3.0 1.2 8.8 0.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Myosin_head PF00063.16 OAJ07217.1 - 2.1e-243 809.3 0.3 2.1e-243 809.3 0.2 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 OAJ07217.1 - 1e-34 118.5 1.8 1e-34 118.5 1.2 2.2 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 OAJ07217.1 - 5.4e-08 31.7 29.9 0.16 11.7 0.3 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.7 OAJ07217.1 - 0.0014 18.3 1.4 0.0014 18.3 1.0 2.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein AAA_22 PF13401.1 OAJ07217.1 - 0.0016 18.5 0.0 0.009 16.1 0.0 2.3 1 0 0 1 1 1 1 AAA domain DivIC PF04977.10 OAJ07217.1 - 0.0046 16.4 6.6 0.0046 16.4 4.5 2.9 2 1 0 2 2 2 1 Septum formation initiator FlaC_arch PF05377.6 OAJ07217.1 - 0.043 13.7 1.2 0.17 11.8 0.8 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) AAA_19 PF13245.1 OAJ07217.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Tropomyosin_1 PF12718.2 OAJ07217.1 - 0.075 12.8 20.6 0.24 11.2 14.3 2.0 1 0 0 1 1 1 0 Tropomyosin like DUF948 PF06103.6 OAJ07217.1 - 0.46 10.3 3.0 1.1 9.2 0.4 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 OAJ07217.1 - 0.49 9.5 3.2 1.6 7.8 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 OAJ07217.1 - 2 8.7 5.6 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Fib_alpha PF08702.5 OAJ07217.1 - 2.2 8.4 14.0 0.055 13.5 4.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.1 OAJ07217.1 - 4.8 7.1 21.4 27 4.7 14.8 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 OAJ07217.1 - 7.7 6.4 24.2 3.5 7.5 5.7 3.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Aha1_N PF09229.6 OAJ07218.1 - 7.1e-28 97.1 0.0 1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 OAJ07218.1 - 9.6e-18 64.4 0.0 2.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 OAJ07218.1 - 0.00039 20.5 0.1 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Med3 PF11593.3 OAJ07218.1 - 0.0053 16.0 7.1 0.0061 15.8 4.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal NUDE_C PF04880.8 OAJ07218.1 - 0.18 12.1 8.0 0.35 11.2 5.6 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Macoilin PF09726.4 OAJ07218.1 - 1.1 7.4 6.7 1.4 7.1 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 OAJ07218.1 - 3.2 6.1 5.0 4.2 5.7 3.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 VHS PF00790.14 OAJ07219.1 - 8.5e-33 112.9 0.1 1.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 OAJ07219.1 - 3.4e-15 55.3 0.3 5.9e-15 54.5 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ07219.1 - 1.1e-14 53.5 0.1 1.8e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 OAJ07219.1 - 6.4e-12 44.7 0.2 1.1e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 OAJ07219.1 - 0.00087 19.2 0.2 0.00087 19.2 0.2 2.6 3 0 0 3 3 3 1 GAT domain Hrs_helical PF12210.3 OAJ07219.1 - 0.068 13.4 0.1 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med26 PF08711.6 OAJ07219.1 - 0.39 10.2 0.8 0.68 9.4 0.0 1.7 2 0 0 2 2 2 0 TFIIS helical bundle-like domain 2OG-FeII_Oxy_3 PF13640.1 OAJ07220.1 - 4.2e-05 24.0 0.1 9.5e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 OAJ07220.1 - 0.0009 19.4 0.1 0.0019 18.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 OAJ07224.1 - 1.4e-36 125.0 0.0 1.7e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Citrate_synt PF00285.16 OAJ07225.1 - 2.3e-114 381.8 0.0 3.2e-114 381.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF2217 PF10265.4 OAJ07226.1 - 6.7 5.3 8.5 9.8 4.8 5.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Methyltransf_16 PF10294.4 OAJ07227.1 - 1.6e-08 34.1 0.0 5.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 OAJ07227.1 - 0.005 17.2 0.0 0.07 13.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ07227.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ07227.1 - 0.13 12.8 0.0 0.66 10.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PAT1 PF09770.4 OAJ07229.1 - 1.9 6.5 20.9 2.1 6.4 14.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 OAJ07229.1 - 2.2 8.0 15.7 2.5 7.8 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ORC6 PF05460.8 OAJ07229.1 - 2.6 7.0 15.2 3.3 6.6 10.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF572 PF04502.8 OAJ07229.1 - 4 6.5 12.0 4.6 6.3 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 OAJ07229.1 - 7.1 5.9 24.9 9.6 5.4 17.3 1.2 1 0 0 1 1 1 0 Vta1 like Dicty_REP PF05086.7 OAJ07229.1 - 7.7 4.1 9.8 8.5 3.9 6.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rhodanese PF00581.15 OAJ07231.1 - 5.6e-08 33.1 0.0 7.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.27 OAJ07232.1 - 6.2e-36 120.9 0.8 7.5e-09 35.1 0.1 7.6 6 1 1 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 OAJ07232.1 - 0.00056 18.1 0.4 0.00099 17.3 0.3 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ECH PF00378.15 OAJ07233.1 - 1e-19 70.6 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PalH PF08733.5 OAJ07234.1 - 0.0023 16.8 2.1 0.0023 16.8 1.5 1.6 2 0 0 2 2 2 1 PalH/RIM21 SdpI PF13630.1 OAJ07234.1 - 1.5 8.6 6.3 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family His_Phos_1 PF00300.17 OAJ07235.1 - 7.3e-19 68.3 0.2 5.3e-18 65.5 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_S30 PF01577.11 OAJ07237.1 - 0.12 11.7 2.2 0.2 11.0 1.5 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Epimerase PF01370.16 OAJ07238.1 - 0.00027 20.4 0.0 0.086 12.2 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 OAJ07238.1 - 0.00056 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAJ07238.1 - 0.0052 15.7 0.0 0.0088 14.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein DUF591 PF04569.9 OAJ07238.1 - 1.1 9.3 3.8 30 4.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function Terpene_synth PF01397.16 OAJ07239.1 - 0.01 15.2 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Glyco_hydro_cc PF11790.3 OAJ07240.1 - 3.3e-40 137.9 0.1 4.5e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Neur_chan_memb PF02932.11 OAJ07240.1 - 0.0098 15.8 1.3 0.019 14.8 0.9 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region GETHR PF05671.6 OAJ07240.1 - 0.11 11.6 9.2 0.5 9.5 1.6 2.3 1 1 1 2 2 2 0 GETHR pentapeptide repeat (5 copies) DPBB_1 PF03330.13 OAJ07242.1 - 6e-12 45.3 0.1 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RhoGAP PF00620.22 OAJ07243.1 - 2.5e-35 121.3 0.0 3.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain GATA PF00320.22 OAJ07244.1 - 6.2e-14 51.0 2.3 1.2e-13 50.0 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger PLA2_B PF01735.13 OAJ07245.1 - 7.6e-11 40.8 0.0 1.7e-05 23.1 0.6 2.4 2 0 0 2 2 2 2 Lysophospholipase catalytic domain PBP1_TM PF14812.1 OAJ07246.1 - 0.22 11.8 4.4 1 9.7 3.0 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_12 PF13424.1 OAJ07247.1 - 6.9e-06 25.9 12.0 0.29 11.0 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 OAJ07247.1 - 4.1e-05 23.1 5.4 2.5 7.7 0.0 5.5 5 1 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 OAJ07247.1 - 8.2e-05 22.2 8.9 1.3 9.0 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ07247.1 - 0.00011 21.6 0.9 2.8 7.6 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ07247.1 - 0.0035 17.6 2.2 6.1 7.5 0.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ07247.1 - 0.016 15.0 0.0 48 4.0 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ07247.1 - 0.054 13.2 0.0 1.5 8.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 OAJ07247.1 - 0.057 13.5 1.8 42 4.3 0.0 4.8 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 OAJ07247.1 - 2.4 9.0 16.7 15 6.5 0.2 7.1 7 2 2 9 9 9 0 Tetratricopeptide repeat Kin17_mid PF10357.4 OAJ07248.1 - 7.2e-46 154.9 0.1 1.5e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein DUF2547 PF10818.3 OAJ07248.1 - 0.47 11.1 6.9 1.1 9.8 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Fungal_trans PF04082.13 OAJ07249.1 - 6.9e-14 51.3 2.5 1.8e-13 49.9 0.0 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ07249.1 - 1.6e-05 24.7 9.4 3e-05 23.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps8 PF12816.2 OAJ07250.1 - 1.6e-51 174.3 0.0 4e-51 173.0 0.0 1.7 1 1 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 OAJ07250.1 - 0.092 12.3 0.3 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS Ebp2 PF05890.7 OAJ07252.1 - 1.1e-72 244.6 10.4 1.1e-72 244.6 7.2 2.4 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TMEM154 PF15102.1 OAJ07253.1 - 0.032 13.9 0.5 0.032 13.9 0.4 2.0 2 0 0 2 2 2 0 TMEM154 protein family Brr6_like_C_C PF10104.4 OAJ07255.1 - 0.0045 16.5 1.9 0.0056 16.1 1.3 1.3 1 1 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain MULE PF10551.4 OAJ07256.1 - 7.2e-05 22.8 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain GST_N_3 PF13417.1 OAJ07257.1 - 1.6e-18 66.7 0.1 3.1e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 OAJ07257.1 - 1.7e-09 37.5 0.1 3.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 OAJ07257.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Kinesin PF00225.18 OAJ07258.1 - 8.4e-97 323.8 6.2 1.2e-52 178.6 0.0 3.5 4 0 0 4 4 4 2 Kinesin motor domain Spc7 PF08317.6 OAJ07258.1 - 6.9e-05 21.6 9.1 6.9e-05 21.6 6.3 11.4 4 2 6 12 12 12 4 Spc7 kinetochore protein Macoilin PF09726.4 OAJ07258.1 - 0.00012 20.5 4.2 0.00012 20.5 2.9 6.5 2 1 3 5 5 5 1 Transmembrane protein Apolipoprotein PF01442.13 OAJ07258.1 - 0.00019 21.0 13.6 0.00019 21.0 9.4 9.9 4 3 4 9 9 9 2 Apolipoprotein A1/A4/E domain SHOCT PF09851.4 OAJ07259.1 - 0.26 10.8 0.0 0.63 9.5 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain NOG1 PF06858.9 OAJ07260.1 - 2.7e-28 97.5 0.2 4.7e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 OAJ07260.1 - 3.1e-28 97.2 2.5 7.6e-28 95.9 1.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 OAJ07260.1 - 5.3e-19 68.2 0.0 1.5e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ07260.1 - 6.9e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 OAJ07260.1 - 8e-05 23.1 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 OAJ07260.1 - 0.00042 20.1 0.0 0.65 9.7 0.0 3.1 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 OAJ07260.1 - 0.00052 19.2 0.0 0.044 12.9 0.0 3.1 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ07260.1 - 0.03 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Myc_N PF01056.13 OAJ07260.1 - 0.083 12.0 4.9 0.17 10.9 3.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region MobB PF03205.9 OAJ07260.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2890 PF11081.3 OAJ07260.1 - 0.19 11.7 19.8 0.31 11.0 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) AAA_17 PF13207.1 OAJ07260.1 - 0.57 11.0 5.5 3.6 8.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain Sporozoite_P67 PF05642.6 OAJ07260.1 - 3.1 5.5 8.1 5 4.8 5.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.22 OAJ07261.1 - 1.3e-18 67.1 0.0 2.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 OAJ07261.1 - 0.0001 22.7 0.1 0.00026 21.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 OAJ07261.1 - 0.052 13.3 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.15 OAJ07261.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease KAR9 PF08580.5 OAJ07261.1 - 3.9 5.6 3.4 1.3 7.1 0.6 1.4 2 0 0 2 2 2 0 Yeast cortical protein KAR9 rve PF00665.21 OAJ07262.1 - 1.5e-08 34.7 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.20 OAJ07263.1 - 7.9e-48 162.8 0.0 1.4e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07263.1 - 1.2e-24 86.8 0.0 3.9e-24 85.1 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ07263.1 - 4.3e-06 25.9 0.0 1.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Dimer_Tnp_hAT PF05699.9 OAJ07264.1 - 1e-19 69.9 0.1 3.2e-19 68.3 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 OAJ07264.1 - 0.13 12.2 0.1 0.5 10.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Mnd1 PF03962.10 OAJ07266.1 - 0.019 14.6 2.5 0.024 14.3 1.7 1.1 1 0 0 1 1 1 0 Mnd1 family Acetyltransf_1 PF00583.19 OAJ07267.1 - 0.0018 18.2 0.1 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DnaJ PF00226.26 OAJ07269.1 - 7.4e-07 28.8 0.1 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 OAJ07269.1 - 0.00015 21.5 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 HhH-GPD PF00730.20 OAJ07271.1 - 5.4e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ07271.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PALP PF00291.20 OAJ07272.1 - 0.05 12.8 1.8 0.09 11.9 1.2 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Metallophos_2 PF12850.2 OAJ07273.1 - 1e-19 70.9 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 OAJ07273.1 - 0.00052 19.4 1.5 0.015 14.7 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase SUZ PF12752.2 OAJ07274.1 - 4.6e-12 46.2 4.7 6.6e-12 45.7 0.8 2.7 3 1 0 3 3 3 1 SUZ domain Glutaredoxin PF00462.19 OAJ07275.1 - 3.7e-19 68.4 0.0 5.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 OAJ07275.1 - 7.3e-05 22.9 0.1 0.00032 20.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 OAJ07275.1 - 0.0014 18.8 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 OAJ07275.1 - 0.0024 17.6 0.1 0.0048 16.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin domain DSBA PF01323.15 OAJ07275.1 - 0.0026 17.3 0.0 0.086 12.3 0.0 2.0 1 1 0 2 2 2 1 DSBA-like thioredoxin domain GST_N_3 PF13417.1 OAJ07275.1 - 0.0029 17.7 0.0 0.0038 17.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 OAJ07275.1 - 0.0044 16.5 0.0 0.0051 16.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 OAJ07275.1 - 0.0065 16.4 0.4 2.5 8.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin GST_N_2 PF13409.1 OAJ07275.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain phiKZ_IP PF12699.2 OAJ07275.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Myb_DNA-binding PF00249.26 OAJ07276.1 - 3.4e-31 107.0 6.6 1.3e-11 44.3 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ07276.1 - 1.6e-27 95.3 1.2 9.7e-12 44.8 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 OAJ07276.1 - 0.62 10.2 4.2 28 4.9 0.0 3.4 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain LAG1-DNAbind PF09271.6 OAJ07277.1 - 7.4e-21 75.0 3.8 1.3e-20 74.3 0.0 2.7 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.5 OAJ07277.1 - 1.4e-08 34.6 0.0 7.1e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain 4HBT PF03061.17 OAJ07278.1 - 2.8e-09 36.9 0.0 4.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 OAJ07278.1 - 0.0027 17.6 0.0 0.0091 15.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4442) UvrD_C PF13361.1 OAJ07279.1 - 1.1e-71 242.2 0.0 6.9e-41 140.8 0.0 2.6 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 OAJ07279.1 - 1.5e-65 221.6 0.4 2.5e-65 220.8 0.3 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 OAJ07279.1 - 1.6e-11 44.2 0.0 4.6e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 OAJ07279.1 - 2.6e-11 43.1 0.1 1.1e-10 41.0 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 OAJ07279.1 - 3.2e-06 26.8 0.1 0.12 11.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 OAJ07279.1 - 0.036 13.4 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ald_Xan_dh_C2 PF02738.13 OAJ07280.1 - 6.3e-176 585.8 0.0 8.6e-176 585.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.17 OAJ07280.1 - 7.6e-30 103.2 0.1 1.9e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.16 OAJ07280.1 - 1e-24 86.8 0.1 8.3e-24 83.9 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.15 OAJ07280.1 - 2.9e-24 84.7 0.1 6e-24 83.7 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.12 OAJ07280.1 - 2.9e-21 75.3 1.5 8.3e-21 73.8 0.0 2.7 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.22 OAJ07280.1 - 3e-06 26.8 0.1 3.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Hamartin PF04388.7 OAJ07280.1 - 1.1 7.8 4.5 1.8 7.1 3.1 1.2 1 0 0 1 1 1 0 Hamartin protein TPR_12 PF13424.1 OAJ07281.1 - 9.9e-05 22.2 7.5 11 5.9 0.0 6.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ07281.1 - 0.0018 18.0 6.1 21 5.3 0.1 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ07281.1 - 0.012 15.1 3.4 28 4.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ07281.1 - 0.042 14.4 5.4 8.7 7.2 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ07282.1 - 0.00045 19.9 3.9 12 6.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ07282.1 - 0.0039 17.0 11.0 1.9 8.4 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 OAJ07282.1 - 0.0042 16.6 1.3 29 4.5 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ07282.1 - 0.023 15.0 1.4 31 5.0 0.0 4.4 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ07282.1 - 0.067 13.8 5.0 13 6.7 0.1 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Fes1 PF08609.5 OAJ07285.1 - 3.6e-16 59.4 0.6 1e-14 54.7 0.3 3.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.17 OAJ07285.1 - 8.9e-05 22.2 4.3 0.7 10.1 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 OAJ07285.1 - 0.0001 22.5 2.1 0.039 14.2 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 OAJ07285.1 - 0.01 14.2 0.7 0.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 OAJ07285.1 - 0.073 13.5 3.3 22 5.7 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat NTP_transferase PF00483.18 OAJ07286.1 - 5.3e-44 150.3 0.0 9.6e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.13 OAJ07286.1 - 3.3e-06 26.7 0.1 5.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Peptidase_C14 PF00656.17 OAJ07287.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Caspase domain OEP PF02321.13 OAJ07287.1 - 0.51 9.8 8.6 0.56 9.7 5.7 1.3 1 1 0 1 1 1 0 Outer membrane efflux protein DUF4662 PF15578.1 OAJ07289.1 - 2.4 7.6 9.3 2.8 7.4 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) DUF3584 PF12128.3 OAJ07289.1 - 3.5 4.8 14.8 3.9 4.6 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 OAJ07289.1 - 8 6.3 10.1 12 5.7 3.4 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 OAJ07289.1 - 8.4 5.3 6.6 9.9 5.1 4.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1777 PF08648.7 OAJ07289.1 - 9.8 5.8 13.0 12 5.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PMT PF02366.13 OAJ07290.1 - 8e-72 241.5 13.0 1.6e-71 240.4 9.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 OAJ07290.1 - 3.5e-40 137.5 0.0 2.6e-39 134.7 0.0 2.4 2 1 0 2 2 2 1 MIR domain zf-RING_2 PF13639.1 OAJ07291.1 - 2.5e-12 46.4 8.2 4.3e-08 32.8 0.6 3.6 3 1 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 OAJ07291.1 - 2.9e-07 30.5 3.9 1.1e-05 25.4 0.7 3.0 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 OAJ07291.1 - 9.7e-05 21.9 4.4 0.045 13.4 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 OAJ07291.1 - 0.00015 21.4 3.3 0.081 12.6 0.3 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 OAJ07291.1 - 0.00019 21.0 0.3 0.00019 21.0 0.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ07291.1 - 0.001 19.0 0.8 0.001 19.0 0.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 OAJ07291.1 - 0.0054 16.5 5.4 0.014 15.2 0.5 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 OAJ07291.1 - 0.13 12.2 4.9 0.14 12.2 1.6 2.4 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.24 OAJ07291.1 - 0.77 9.5 10.6 0.58 9.9 1.4 3.5 3 0 0 3 3 3 0 PHD-finger zf-MIZ PF02891.15 OAJ07291.1 - 2.4 7.7 9.2 0.43 10.1 1.2 2.9 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Thioredoxin PF00085.15 OAJ07292.1 - 2.3e-27 94.7 0.0 2.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 OAJ07292.1 - 1.3e-07 31.6 0.1 1.6e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 OAJ07292.1 - 4.1e-06 26.7 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 OAJ07292.1 - 7.1e-06 26.1 0.0 5.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 OAJ07292.1 - 4.1e-05 23.2 0.1 0.00011 21.8 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 OAJ07292.1 - 0.00022 20.7 0.2 0.0011 18.5 0.1 1.8 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.11 OAJ07292.1 - 0.0003 20.2 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 OAJ07292.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF2847 PF11009.3 OAJ07292.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) YfzA PF14118.1 OAJ07293.1 - 0.00064 19.7 0.6 0.16 12.1 0.1 2.7 2 0 0 2 2 2 2 YfzA-like protein TRAM_LAG1_CLN8 PF03798.11 OAJ07293.1 - 0.008 15.7 3.5 0.0096 15.4 1.8 1.6 1 1 1 2 2 2 1 TLC domain Serglycin PF04360.7 OAJ07294.1 - 0.0099 15.6 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Serglycin BSP_II PF05432.6 OAJ07294.1 - 0.59 9.3 10.2 0.35 10.1 5.8 1.5 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) WLM PF08325.5 OAJ07295.1 - 1.6e-41 142.2 0.0 4.5e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.13 OAJ07295.1 - 5.2e-07 28.6 1.8 8.2e-07 28.0 1.3 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 OAJ07295.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF2458 PF10454.4 OAJ07296.1 - 0.0052 16.6 2.1 0.0052 16.6 1.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2458) DUF2229 PF09989.4 OAJ07296.1 - 1.1 8.6 4.1 0.44 9.9 0.1 2.1 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) BTV_NS2 PF04514.7 OAJ07296.1 - 2.4 6.9 11.4 1.8 7.3 1.8 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 TipAS PF07739.8 OAJ07296.1 - 5.3 7.3 10.4 0.79 10.0 1.9 2.4 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain NAD_binding_10 PF13460.1 OAJ07301.1 - 2.6e-09 37.3 0.0 1.3e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 OAJ07301.1 - 7.9e-05 22.2 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 OAJ07301.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 OAJ07301.1 - 0.059 12.2 0.0 0.3 9.9 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 OAJ07301.1 - 0.093 12.6 0.0 0.26 11.1 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Tcp11 PF05794.8 OAJ07303.1 - 1.1e-06 27.6 0.3 0.0018 17.0 0.0 3.3 2 2 0 2 2 2 2 T-complex protein 11 NAD_binding_4 PF07993.7 OAJ07304.1 - 1.5e-25 89.5 0.0 2.7e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 OAJ07304.1 - 1.7e-20 72.8 0.0 9.8e-20 70.3 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 OAJ07304.1 - 1.6e-13 50.6 0.0 3.2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 OAJ07304.1 - 2.1e-05 24.4 0.4 0.13 12.1 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 OAJ07304.1 - 8.3e-05 22.3 0.1 0.00047 19.8 0.0 2.2 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 OAJ07304.1 - 0.00027 19.7 0.0 0.00074 18.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 OAJ07304.1 - 0.071 11.9 0.0 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Coatomer_WDAD PF04053.9 OAJ07305.1 - 2.6e-147 491.2 0.0 4.6e-147 490.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 OAJ07305.1 - 3.6e-51 169.3 9.1 4.9e-11 42.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 OAJ07305.1 - 0.017 13.2 1.2 3 5.8 0.1 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 YmzC PF14157.1 OAJ07305.1 - 0.11 12.3 0.0 1.9 8.3 0.0 3.0 3 0 0 3 3 3 0 YmzC-like protein DUF4449 PF14613.1 OAJ07306.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 4.0 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) ATG_C PF09333.6 OAJ07306.1 - 0.042 14.0 0.3 0.23 11.6 0.2 2.3 1 0 0 1 1 1 0 ATG C terminal domain ATP13 PF12921.2 OAJ07306.1 - 0.07 12.4 0.0 0.58 9.5 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ATPase expression PRESAN PF09687.5 OAJ07306.1 - 0.13 12.3 0.1 1.8 8.6 0.0 2.7 2 1 0 2 2 2 0 Plasmodium RESA N-terminal PilO PF04350.8 OAJ07306.1 - 0.14 12.0 3.6 2.5 7.9 0.2 2.8 2 0 0 2 2 2 0 Pilus assembly protein, PilO Phage_connect_1 PF05135.8 OAJ07306.1 - 0.15 12.2 2.1 0.88 9.7 0.3 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Anti-adapt_IraP PF10796.4 OAJ07306.1 - 0.55 10.6 0.0 0.55 10.6 0.0 3.8 4 2 0 5 5 5 0 Sigma-S stabilisation anti-adaptor protein Syntaxin_2 PF14523.1 OAJ07306.1 - 3.8 7.5 7.2 51 3.9 0.0 4.6 4 1 0 5 5 5 0 Syntaxin-like protein EF_TS PF00889.14 OAJ07307.1 - 6.9e-16 58.2 0.0 1.4e-13 50.6 0.0 2.9 3 0 0 3 3 3 2 Elongation factor TS Nucleoporin_C PF03177.9 OAJ07308.1 - 1e-78 265.3 11.9 1.6e-78 264.7 8.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ07308.1 - 8.5e-55 186.1 0.0 1.2e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Inhibitor_G39P PF11417.3 OAJ07308.1 - 0.044 13.7 0.1 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P ArsB PF02040.10 OAJ07309.1 - 3.8e-14 52.4 28.3 1.2e-08 34.3 5.8 2.4 3 0 0 3 3 3 2 Arsenical pump membrane protein DUF3357 PF11837.3 OAJ07309.1 - 0.71 9.7 4.5 2.5 7.9 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Peptidase_M28 PF04389.12 OAJ07310.1 - 3.9e-30 104.9 0.0 6.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SMC_N PF02463.14 OAJ07311.1 - 7.1e-23 80.9 0.2 1.6e-22 79.8 0.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 OAJ07311.1 - 6.3e-13 49.5 19.8 6.3e-13 49.5 13.7 5.3 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.1 OAJ07311.1 - 2.3e-07 31.0 0.1 2.6e-06 27.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 OAJ07311.1 - 2.2e-05 23.8 0.1 0.00014 21.3 0.0 2.3 2 1 1 3 3 3 1 P-loop containing region of AAA domain AAA PF00004.24 OAJ07311.1 - 0.021 15.0 1.2 0.9 9.7 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 OAJ07311.1 - 0.022 14.1 0.3 0.18 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 OAJ07311.1 - 0.078 13.2 0.0 0.078 13.2 0.0 5.3 3 2 0 3 3 2 0 ABC transporter AAA_19 PF13245.1 OAJ07311.1 - 0.096 12.4 0.1 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_15 PF13175.1 OAJ07311.1 - 0.16 11.0 0.0 0.16 11.0 0.0 3.0 3 1 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.1 OAJ07311.1 - 0.31 11.1 3.0 1.6 8.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.1 OAJ07311.1 - 0.34 9.3 0.0 0.34 9.3 0.0 5.0 3 2 1 4 4 4 0 AAA domain ArfGap PF01412.13 OAJ07314.1 - 2.7e-32 111.0 0.1 6.7e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ERM PF00769.14 OAJ07314.1 - 0.089 12.3 9.5 0.17 11.3 6.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Pkinase PF00069.20 OAJ07315.1 - 3e-40 138.0 0.2 3.2e-23 82.1 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07315.1 - 1e-11 44.4 0.4 7.4e-09 35.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 OAJ07315.1 - 0.29 9.8 0.0 0.41 9.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 OAJ07316.1 - 4.6e-73 246.3 0.0 1.9e-45 155.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2088 PF09861.4 OAJ07316.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) DUF3605 PF12239.3 OAJ07317.1 - 3.2e-18 66.0 0.1 5.3e-14 52.3 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) Vma12 PF11712.3 OAJ07319.1 - 3.8e-29 101.2 0.1 6.5e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.4 OAJ07319.1 - 5.2e-08 32.2 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit DUF1772 PF08592.6 OAJ07319.1 - 0.0032 17.2 3.3 0.0054 16.4 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) PA_decarbox PF05870.6 OAJ07319.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Band_7 PF01145.20 OAJ07320.1 - 7.5e-25 87.8 3.1 1e-24 87.4 1.6 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family LigB PF02900.13 OAJ07321.1 - 2.1e-29 102.3 0.1 1.1e-28 100.0 0.1 1.8 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.7 OAJ07321.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease DUF3368 PF11848.3 OAJ07323.1 - 0.0092 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3368) HSCB_C PF07743.8 OAJ07324.1 - 5.9e-13 49.0 2.5 5.9e-13 49.0 1.7 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 OAJ07324.1 - 2.4e-11 43.1 0.0 4.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.7 OAJ07324.1 - 0.016 15.0 4.4 0.037 13.8 3.0 1.7 1 0 0 1 1 1 0 cwf21 domain RNA_pol_Rpc34 PF05158.7 OAJ07324.1 - 0.05 12.7 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit CNTF PF01110.12 OAJ07324.1 - 0.18 11.0 2.5 0.54 9.5 1.7 1.7 1 1 0 1 1 1 0 Ciliary neurotrophic factor SLT_L PF14718.1 OAJ07324.1 - 6.5 6.6 7.0 40 4.1 0.2 3.4 3 0 0 3 3 3 0 Soluble lytic murein transglycosylase L domain EF-hand_1 PF00036.27 OAJ07325.1 - 1.4e-27 92.8 14.9 8.8e-08 30.9 0.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ07325.1 - 2.4e-23 82.0 6.4 1e-11 44.8 1.5 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 OAJ07325.1 - 3.9e-21 72.9 8.8 3.1e-05 23.4 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ07325.1 - 1.1e-19 68.7 16.1 5e-06 25.6 1.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 OAJ07325.1 - 4.1e-13 48.7 17.6 0.00027 20.5 2.0 4.6 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 OAJ07325.1 - 6.3e-05 22.9 0.0 0.0074 16.3 0.0 2.4 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 OAJ07325.1 - 0.0002 21.0 6.8 0.0085 15.8 0.5 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 OAJ07325.1 - 0.00086 19.1 0.4 0.31 10.9 0.1 3.5 3 1 1 4 4 4 1 EF-hand domain VCBS PF13517.1 OAJ07325.1 - 0.074 13.4 1.1 7.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RTA1 PF04479.8 OAJ07326.1 - 1.6e-26 93.1 6.2 2.5e-26 92.5 4.3 1.3 1 0 0 1 1 1 1 RTA1 like protein SelR PF01641.13 OAJ07327.1 - 3.6e-52 175.2 0.1 4.4e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 OAJ07327.1 - 0.02 14.7 0.1 0.061 13.1 0.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.1 OAJ07327.1 - 0.047 13.5 2.4 0.11 12.3 0.2 2.5 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2076 PF09849.4 OAJ07327.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L37e PF01907.14 OAJ07327.1 - 1.7 8.4 4.5 1.7 8.5 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e AAA PF00004.24 OAJ07328.1 - 1.1e-90 300.6 0.0 4.2e-46 156.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 OAJ07328.1 - 6.4e-14 51.5 0.0 9.4e-07 28.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 OAJ07328.1 - 1e-11 45.0 0.2 0.0031 17.6 0.0 5.1 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.9 OAJ07328.1 - 9.4e-11 41.9 0.0 0.00042 20.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 OAJ07328.1 - 1.1e-10 41.4 0.2 0.0014 18.3 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 OAJ07328.1 - 1.5e-10 41.8 0.0 1.5e-05 25.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 OAJ07328.1 - 1.2e-09 38.2 0.1 0.0053 16.6 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 OAJ07328.1 - 1.6e-09 38.0 8.7 0.0003 20.8 0.3 4.4 4 2 0 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 OAJ07328.1 - 2.5e-09 36.3 0.0 2.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 OAJ07328.1 - 1.3e-08 34.8 0.0 0.0055 16.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 OAJ07328.1 - 4.9e-08 32.6 0.7 0.013 15.2 0.0 3.8 2 1 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 OAJ07328.1 - 6.5e-08 31.9 0.0 0.011 14.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 OAJ07328.1 - 1.7e-07 30.8 0.0 0.013 14.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 OAJ07328.1 - 3.3e-07 30.1 1.2 0.033 13.8 0.1 4.1 3 1 0 4 4 4 2 NACHT domain Mg_chelatase PF01078.16 OAJ07328.1 - 3.7e-07 29.5 2.1 0.017 14.2 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 OAJ07328.1 - 8.4e-07 29.1 0.0 0.065 13.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 OAJ07328.1 - 9.4e-07 28.9 0.0 0.028 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ07328.1 - 2.2e-06 27.2 7.3 0.27 10.6 0.1 5.0 3 2 2 5 5 4 2 AAA domain ABC_tran PF00005.22 OAJ07328.1 - 3.5e-06 27.3 0.2 0.082 13.2 0.0 3.2 3 0 0 3 3 3 2 ABC transporter AAA_3 PF07726.6 OAJ07328.1 - 1.7e-05 24.4 0.0 0.043 13.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ07328.1 - 2.8e-05 24.4 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 OAJ07328.1 - 3.2e-05 23.9 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 OAJ07328.1 - 0.00012 21.3 0.0 1.4 7.9 0.0 3.2 3 0 0 3 3 3 1 KaiC Sigma54_activat PF00158.21 OAJ07328.1 - 0.00015 21.2 0.0 0.44 10.0 0.0 3.7 4 0 0 4 4 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 OAJ07328.1 - 0.00024 20.7 0.0 0.69 9.3 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 OAJ07328.1 - 0.00074 18.4 0.1 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Cytidylate_kin2 PF13189.1 OAJ07328.1 - 0.0011 18.9 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 OAJ07328.1 - 0.0013 18.6 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase Parvo_NS1 PF01057.12 OAJ07328.1 - 0.002 17.0 0.1 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 OAJ07328.1 - 0.0022 17.2 0.2 1 8.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 OAJ07328.1 - 0.0033 16.3 0.0 0.028 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 OAJ07328.1 - 0.0034 17.1 0.0 1.5 8.4 0.0 2.9 2 1 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 OAJ07328.1 - 0.0035 17.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.10 OAJ07328.1 - 0.0043 15.8 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 OAJ07328.1 - 0.0043 16.6 0.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 OAJ07328.1 - 0.013 14.3 0.0 1.4 7.6 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.1 OAJ07328.1 - 0.021 14.4 0.2 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Lzipper-MIP1 PF14389.1 OAJ07328.1 - 0.028 14.5 0.3 0.15 12.1 0.1 2.3 2 0 0 2 2 1 0 Leucine-zipper of ternary complex factor MIP1 NTPase_1 PF03266.10 OAJ07328.1 - 0.029 14.0 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 OAJ07328.1 - 0.076 12.5 0.0 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 OAJ07328.1 - 0.24 10.3 0.0 19 4.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DAP3 PF10236.4 OAJ07328.1 - 0.24 10.2 0.3 14 4.5 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Bac_DnaA PF00308.13 OAJ07328.1 - 0.25 10.9 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein IMS PF00817.15 OAJ07330.1 - 2.7e-28 98.6 0.0 4.9e-28 97.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 OAJ07330.1 - 0.0096 15.9 0.0 0.031 14.2 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif MMR_HSR1 PF01926.18 OAJ07331.1 - 2.6e-16 59.6 0.0 1.2e-14 54.1 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 OAJ07331.1 - 7.7e-06 25.2 0.0 6.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 OAJ07331.1 - 0.00015 20.9 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ07331.1 - 0.0013 17.8 0.0 0.0045 16.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Nop14 PF04147.7 OAJ07331.1 - 0.0099 13.8 19.1 0.014 13.3 13.2 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 OAJ07331.1 - 0.026 13.1 0.2 0.032 12.8 0.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.7 OAJ07331.1 - 0.18 11.0 21.9 0.33 10.1 15.2 1.3 1 0 0 1 1 1 0 SDA1 Miro PF08477.8 OAJ07331.1 - 0.23 11.9 1.3 0.35 11.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 OAJ07331.1 - 0.96 9.2 6.1 0.12 12.1 0.2 2.3 2 1 0 2 2 2 0 Dynamin family Spore_coat_CotO PF14153.1 OAJ07331.1 - 2.6 7.4 10.1 0.6 9.5 4.4 1.7 2 0 0 2 2 2 0 Spore coat protein CotO Ribosomal_60s PF00428.14 OAJ07331.1 - 4.1 7.8 31.8 0.4 11.0 16.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDC45 PF02724.9 OAJ07331.1 - 4.8 5.0 19.8 7.1 4.5 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 OAJ07331.1 - 7.5 5.6 14.0 17 4.4 9.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 OAJ07331.1 - 8.6 5.6 20.4 15 4.8 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PCI_Csn8 PF10075.4 OAJ07332.1 - 1.5e-33 115.6 0.0 2.1e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 OAJ07332.1 - 2.1e-30 105.8 0.1 2.6e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Abhydrolase_3 PF07859.8 OAJ07333.1 - 4.5e-14 52.5 0.1 1e-09 38.2 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07333.1 - 7.8e-09 35.4 0.9 1.1e-07 31.6 0.6 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ07333.1 - 1.1e-07 31.3 0.1 3e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 OAJ07333.1 - 0.0003 19.6 0.0 0.00048 18.9 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 OAJ07333.1 - 0.17 11.2 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MRP-S25 PF13741.1 OAJ07334.1 - 6.2e-48 163.2 0.1 1.2e-47 162.3 0.1 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 OAJ07334.1 - 0.0001 22.1 2.5 0.015 15.2 0.1 2.6 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S23 GTP_EFTU PF00009.22 OAJ07335.1 - 6.8e-48 162.6 0.0 1.2e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 OAJ07335.1 - 1.6e-21 75.8 0.3 4.2e-10 39.3 0.0 2.7 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.19 OAJ07335.1 - 1.8e-17 62.9 0.3 3.9e-15 55.4 0.2 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 OAJ07335.1 - 3e-07 30.4 0.0 7.7e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ07335.1 - 0.055 13.0 0.0 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G, domain IV Helicase_C PF00271.26 OAJ07336.1 - 4.5e-11 42.4 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ07336.1 - 0.0064 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NmrA PF05368.8 OAJ07337.1 - 8e-10 38.3 0.2 0.00017 20.9 0.0 3.1 3 0 0 3 3 3 3 NmrA-like family DUF1416 PF07210.7 OAJ07337.1 - 0.16 11.5 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) OGG_N PF07934.7 OAJ07338.1 - 9.1e-23 80.4 0.0 1.1e-18 67.3 0.0 2.3 2 0 0 2 2 2 2 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 OAJ07338.1 - 6.2e-11 42.5 0.0 3.9e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 OAJ07338.1 - 0.015 14.9 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif GN3L_Grn1 PF08701.6 OAJ07339.1 - 3.5e-19 68.4 21.4 3.5e-19 68.4 14.8 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase Spt5_N PF11942.3 OAJ07339.1 - 0.0022 18.5 6.0 0.0022 18.5 4.2 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal RNA_pol_3_Rpc31 PF11705.3 OAJ07339.1 - 7.9 6.3 19.8 17 5.2 13.7 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cullin_binding PF03556.10 OAJ07340.1 - 5.1e-31 107.2 0.1 8.9e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 OAJ07340.1 - 1.8e-09 36.9 0.0 3.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain LisH PF08513.6 OAJ07342.1 - 0.0004 20.0 0.0 0.00072 19.2 0.0 1.4 1 0 0 1 1 1 1 LisH Reo_sigmaC PF04582.7 OAJ07343.1 - 8.6 5.4 19.9 0.17 11.0 0.5 4.0 1 1 2 4 4 4 0 Reovirus sigma C capsid protein WD40 PF00400.27 OAJ07344.1 - 2.9e-10 39.6 13.0 0.057 13.3 0.1 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 OAJ07344.1 - 0.002 17.6 0.1 0.019 14.4 0.0 2.1 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.1 OAJ07344.1 - 0.0022 18.2 0.8 6.7 7.1 0.0 4.7 5 0 0 5 5 5 1 PQQ-like domain BUD22 PF09073.5 OAJ07344.1 - 0.22 10.5 34.0 0.17 10.9 21.2 2.0 2 0 0 2 2 2 0 BUD22 SurE PF01975.12 OAJ07346.1 - 8.1e-40 136.2 0.0 2.1e-39 134.8 0.0 1.6 1 1 0 1 1 1 1 Survival protein SurE Clp1 PF06807.9 OAJ07347.1 - 4.9e-19 68.8 0.0 3.9e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 AAA_29 PF13555.1 OAJ07347.1 - 0.0027 17.2 0.0 0.0079 15.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 OAJ07347.1 - 0.0088 16.5 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 OAJ07347.1 - 0.015 14.9 0.0 0.086 12.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 OAJ07347.1 - 0.033 14.1 0.1 3.5 7.6 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 OAJ07347.1 - 0.036 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 OAJ07347.1 - 0.077 12.8 0.1 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Dynamin family DUF4050 PF13259.1 OAJ07348.1 - 0.027 14.3 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) MDMPI_N PF11716.3 OAJ07348.1 - 4.1 7.8 12.8 1.2e+02 3.0 8.9 2.7 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Ribonuc_2-5A PF06479.7 OAJ07349.1 - 9.7e-42 141.8 0.0 1.5e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 OAJ07349.1 - 1.2e-41 142.6 0.0 1.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07349.1 - 9.3e-20 70.7 0.0 5.2e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 OAJ07349.1 - 0.004 16.2 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 OAJ07349.1 - 0.011 15.2 0.1 0.088 12.3 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat YrbL-PhoP_reg PF10707.4 OAJ07349.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FAD-oxidase_C PF02913.14 OAJ07350.1 - 2.7e-58 197.2 0.0 4e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 OAJ07350.1 - 2.3e-35 121.0 0.8 4.2e-35 120.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.9 OAJ07350.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain EpuA PF11772.3 OAJ07350.1 - 0.13 11.7 0.4 0.4 10.1 0.3 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Ilar_coat PF01787.11 OAJ07350.1 - 0.14 11.7 0.8 0.83 9.1 0.0 2.5 2 1 1 3 3 3 0 Ilarvirus coat protein CHCH PF06747.8 OAJ07351.1 - 3.1e-05 23.7 4.9 3.1e-05 23.7 3.4 2.4 2 1 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 OAJ07351.1 - 0.25 11.3 9.4 0.26 11.3 2.6 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 PolC_DP2 PF03833.8 OAJ07351.1 - 0.44 8.1 2.0 0.45 8.1 1.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3128 PF11326.3 OAJ07351.1 - 0.83 9.8 5.7 0.4 10.8 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Aminotran_5 PF00266.14 OAJ07352.1 - 3.8e-22 78.5 0.0 5.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 OAJ07352.1 - 8.2e-06 25.0 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Nop14 PF04147.7 OAJ07352.1 - 0.077 10.9 7.8 0.11 10.4 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 OAJ07352.1 - 0.8 9.4 7.8 1.5 8.5 5.4 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SMN PF06003.7 OAJ07352.1 - 0.96 8.5 8.9 0.57 9.2 3.8 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Lin-8 PF03353.10 OAJ07352.1 - 2.3 7.4 7.4 4.2 6.5 5.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 OAJ07352.1 - 4.6 5.6 18.7 7.8 4.8 13.0 1.2 1 0 0 1 1 1 0 Daxx Family NUDIX PF00293.23 OAJ07353.1 - 8.3e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Lon_C PF05362.8 OAJ07354.1 - 8.8e-65 217.8 0.1 1.8e-64 216.8 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 OAJ07354.1 - 1.1e-22 80.6 0.0 2.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 OAJ07354.1 - 1.3e-09 37.9 0.0 2.6e-08 33.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 OAJ07354.1 - 5.2e-09 35.6 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 OAJ07354.1 - 5.5e-06 26.4 0.3 2.9e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain LON PF02190.11 OAJ07354.1 - 9.9e-06 25.3 0.0 2.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_17 PF13207.1 OAJ07354.1 - 8.2e-05 23.4 0.0 0.00032 21.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ07354.1 - 0.00032 20.8 0.2 0.012 15.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 OAJ07354.1 - 0.00083 19.3 0.0 0.0038 17.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 OAJ07354.1 - 0.00087 19.1 0.1 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 OAJ07354.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 OAJ07354.1 - 0.0076 15.9 0.4 0.022 14.4 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 OAJ07354.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 OAJ07354.1 - 0.01 14.9 0.0 0.032 13.2 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 OAJ07354.1 - 0.017 14.2 0.1 0.046 12.8 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 OAJ07354.1 - 0.017 13.7 0.0 0.49 9.0 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain RNA_helicase PF00910.17 OAJ07354.1 - 0.024 14.8 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 OAJ07354.1 - 0.031 13.6 0.0 0.086 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 OAJ07354.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 OAJ07354.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 OAJ07354.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.1 OAJ07354.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 OAJ07354.1 - 0.07 12.7 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 OAJ07354.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 OAJ07354.1 - 0.21 10.7 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MCM PF00493.18 OAJ07355.1 - 1.1e-134 448.3 0.1 1.1e-134 448.3 0.1 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MFS_1 PF07690.11 OAJ07355.1 - 8.6e-38 129.9 31.6 8.2e-37 126.7 18.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MCM_N PF14551.1 OAJ07355.1 - 2.9e-18 66.5 0.0 6.7e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Sugar_tr PF00083.19 OAJ07355.1 - 1.8e-11 43.2 7.4 1.8e-11 43.2 5.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Mg_chelatase PF01078.16 OAJ07355.1 - 6.9e-07 28.6 0.0 4.5e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 OAJ07355.1 - 0.0072 15.9 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 OAJ07355.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 OAJ07355.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF697 PF05128.7 OAJ07355.1 - 0.071 12.6 1.4 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF697) SapB_1 PF05184.10 OAJ07355.1 - 0.72 9.7 1.5 3 7.7 0.4 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 AIG2 PF06094.7 OAJ07357.1 - 1.6e-12 47.7 0.0 2.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family DUF2456 PF10445.4 OAJ07359.1 - 2.9e-21 75.1 3.0 6.2e-21 74.1 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) Mem_trans PF03547.13 OAJ07359.1 - 0.0048 15.2 0.4 0.0076 14.5 0.0 1.5 2 0 0 2 2 2 1 Membrane transport protein zf-H2C2_2 PF13465.1 OAJ07361.1 - 4.2e-06 26.7 9.4 0.00019 21.5 0.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ07361.1 - 0.0015 18.7 12.6 0.052 13.9 0.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ07361.1 - 0.069 13.5 10.0 1 9.8 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger SET PF00856.23 OAJ07362.1 - 0.00015 22.1 0.0 0.0097 16.2 0.0 2.6 1 1 0 1 1 1 1 SET domain Cmc1 PF08583.5 OAJ07363.1 - 0.02 14.6 0.6 0.062 13.0 0.2 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 OAJ07363.1 - 0.029 14.1 0.2 0.064 13.1 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CHCH PF06747.8 OAJ07363.1 - 1.5 8.8 4.3 7.3 6.6 2.9 1.9 1 1 1 2 2 2 0 CHCH domain Rhodanese PF00581.15 OAJ07364.1 - 3.5e-17 62.7 0.0 5.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Snf7 PF03357.16 OAJ07366.1 - 2.3e-19 69.4 13.7 2.8e-19 69.1 9.5 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 OAJ07366.1 - 0.0018 17.6 2.1 0.0027 17.1 1.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SYCE1 PF15233.1 OAJ07366.1 - 0.18 11.7 6.9 0.035 14.0 2.2 1.8 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF2416 PF10315.4 OAJ07367.1 - 7.9e-09 35.7 2.0 1.8e-08 34.5 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Ribosomal_S13 PF00416.17 OAJ07368.1 - 3e-24 85.5 0.0 4.1e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 OAJ07368.1 - 0.00037 19.1 0.1 0.00049 18.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FAM70 PF14967.1 OAJ07368.1 - 0.23 10.6 3.5 0.31 10.1 2.4 1.2 1 0 0 1 1 1 0 FAM70 protein Proteasome PF00227.21 OAJ07369.1 - 4.8e-40 136.8 0.1 5.5e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit zf-CCHC PF00098.18 OAJ07370.1 - 1.1e-30 104.1 45.4 8.8e-07 28.5 0.3 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 OAJ07370.1 - 3.2e-09 36.3 38.1 0.0071 15.9 0.9 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.1 OAJ07370.1 - 0.00035 20.2 34.2 0.078 12.7 0.3 6.0 2 2 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ07370.1 - 0.00039 19.8 5.7 0.023 14.1 0.1 5.7 4 2 2 6 6 6 2 Zinc knuckle zf-CCHC_5 PF14787.1 OAJ07370.1 - 0.016 14.7 1.8 0.016 14.7 1.3 4.6 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger RRM_1 PF00076.17 OAJ07371.1 - 4.1e-28 96.8 0.1 2e-16 59.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ07371.1 - 8.4e-16 57.7 0.1 4.5e-10 39.3 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ07371.1 - 6.9e-12 45.0 0.0 4.7e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ07371.1 - 9.8e-05 22.1 0.0 9.8e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 OAJ07371.1 - 0.0032 17.1 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 OAJ07371.1 - 0.071 12.8 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Suf PF05843.9 OAJ07371.1 - 3.3 7.3 17.4 0.54 9.9 4.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EXS PF03124.9 OAJ07372.1 - 2.2e-86 290.0 26.3 3e-86 289.5 18.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 OAJ07372.1 - 1e-39 136.9 1.4 1.1e-39 136.8 0.1 1.8 2 1 0 2 2 2 1 SPX domain DUF1993 PF09351.5 OAJ07372.1 - 0.039 13.8 2.9 0.76 9.6 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Abhydrolase_6 PF12697.2 OAJ07373.1 - 3e-13 50.1 1.8 7.8e-13 48.8 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 OAJ07373.1 - 0.00048 19.8 0.1 0.0043 16.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family He_PIG PF05345.7 OAJ07375.1 - 1.7e-11 43.9 19.0 5.1e-07 29.6 0.3 4.5 4 0 0 4 4 4 3 Putative Ig domain MAGE_N PF12440.3 OAJ07376.1 - 0.023 14.9 2.0 0.046 14.0 1.3 1.7 1 1 0 1 1 1 0 Melanoma associated antigen family N terminal DUF3071 PF11268.3 OAJ07376.1 - 0.078 12.7 2.4 0.11 12.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) PPR_2 PF13041.1 OAJ07377.1 - 1.4e-11 44.1 0.1 6.7e-11 41.9 0.0 2.2 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 OAJ07377.1 - 1.6e-05 24.8 0.0 0.023 14.9 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.15 OAJ07377.1 - 0.15 12.0 1.0 0.84 9.7 0.0 2.9 4 0 0 4 4 4 0 PPR repeat Dus PF01207.12 OAJ07378.1 - 1.3e-47 162.1 0.0 4.5e-32 111.1 0.0 2.2 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 OAJ07378.1 - 1.5e-06 27.7 3.6 0.0017 17.9 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_hydro_cc PF11790.3 OAJ07379.1 - 1.5e-50 171.8 2.3 2.1e-50 171.3 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core GLE1 PF07817.8 OAJ07381.1 - 1.3e-60 204.5 0.0 1.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Ycf1 PF05758.7 OAJ07381.1 - 7.2 4.1 11.7 10 3.7 8.1 1.1 1 0 0 1 1 1 0 Ycf1 Shugoshin_C PF07557.6 OAJ07393.1 - 6.9e-20 70.1 35.1 5.8e-11 41.6 3.6 4.2 4 0 0 4 4 4 3 Shugoshin C terminus RNA_pol_3_Rpc31 PF11705.3 OAJ07393.1 - 0.0024 17.8 2.3 0.0024 17.8 1.6 3.7 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.5 OAJ07393.1 - 5.9 5.8 48.4 0.88 8.5 5.8 3.7 3 0 0 3 3 3 0 BUD22 Bystin PF05291.6 OAJ07394.1 - 1.5e-128 428.0 0.0 2e-128 427.5 0.0 1.1 1 0 0 1 1 1 1 Bystin Daxx PF03344.10 OAJ07394.1 - 0.16 10.4 11.0 0.27 9.6 7.6 1.3 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 OAJ07394.1 - 2.2 7.7 11.4 4 6.9 7.9 1.4 1 0 0 1 1 1 0 PPP4R2 Glyco_hydro_47 PF01532.15 OAJ07395.1 - 2.1e-145 484.8 0.0 2.6e-145 484.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PXA PF02194.10 OAJ07397.1 - 2.1e-12 47.0 0.0 2.6e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.7 OAJ07397.1 - 8.4e-06 25.8 0.0 2.2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.4 OAJ07397.1 - 0.18 11.4 2.4 0.34 10.5 1.7 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) ELO PF01151.13 OAJ07398.1 - 8.8e-56 188.9 12.1 1e-55 188.7 8.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Methyltransf_23 PF13489.1 OAJ07400.1 - 6.7e-10 38.9 0.0 1.9e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ07400.1 - 5e-09 36.5 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ07400.1 - 2.6e-08 34.2 0.0 4.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ07400.1 - 6.8e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ07400.1 - 0.0029 18.1 0.0 0.007 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 OAJ07400.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 1 0 1 1 1 0 Putative methyltransferase Vac_ImportDeg PF09783.4 OAJ07401.1 - 8.1e-53 178.5 0.0 7.5e-49 165.6 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein DZR PF12773.2 OAJ07401.1 - 0.022 14.5 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon TFIIA_gamma_N PF02268.11 OAJ07402.1 - 6.3e-26 89.7 0.1 8.5e-26 89.2 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 OAJ07402.1 - 1.6e-22 79.0 0.2 2.2e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit DUF2414 PF10309.4 OAJ07403.1 - 0.00045 19.8 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 OAJ07403.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 OAJ07403.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif DAO PF01266.19 OAJ07404.1 - 3.7e-57 193.8 1.3 7.6e-57 192.8 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 OAJ07404.1 - 0.00011 22.0 0.0 0.084 12.7 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ07404.1 - 0.00046 20.1 0.5 0.0011 18.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 OAJ07404.1 - 0.00083 18.0 0.5 0.0069 15.0 0.4 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 OAJ07404.1 - 0.0025 16.7 0.1 0.12 11.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 OAJ07404.1 - 0.0031 17.3 0.1 0.58 9.9 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ07404.1 - 0.0041 16.2 0.2 0.011 14.8 0.2 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 OAJ07404.1 - 0.025 13.4 1.7 0.036 12.9 1.1 1.3 1 1 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 OAJ07404.1 - 0.031 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase ADH_zinc_N PF00107.21 OAJ07406.1 - 3.1e-29 101.1 0.1 5.5e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ07406.1 - 1.8e-13 51.4 0.6 5.1e-13 50.0 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ07406.1 - 1.6e-09 37.5 0.0 7.9e-08 32.0 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PPR_3 PF13812.1 OAJ07407.1 - 2.3e-16 58.5 14.4 0.0034 17.5 0.0 8.6 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 OAJ07407.1 - 2.7e-15 56.0 0.0 0.0057 16.6 0.0 6.8 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.15 OAJ07407.1 - 5.5e-07 29.1 11.5 0.063 13.2 0.0 7.0 7 1 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 OAJ07407.1 - 1.5e-06 27.5 10.6 0.0025 17.2 0.1 5.1 6 1 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 OAJ07407.1 - 0.0073 16.8 4.6 9.2 7.2 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Romo1 PF10247.4 OAJ07408.1 - 9.1e-21 73.8 11.0 1.3e-20 73.3 7.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Ndc1_Nup PF09531.5 OAJ07408.1 - 0.013 13.9 0.7 0.013 13.9 0.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 OAJ07408.1 - 0.051 13.4 1.2 0.058 13.2 0.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RCR PF12273.3 OAJ07408.1 - 0.12 12.9 12.8 0.16 12.5 8.9 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 OAJ07408.1 - 0.14 11.6 2.4 0.18 11.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Med15 PF09606.5 OAJ07408.1 - 5.4 5.0 28.4 6.7 4.7 19.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAS2 PF02187.12 OAJ07409.1 - 1.9e-08 33.9 0.0 4.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain POTRA_1 PF08478.5 OAJ07409.1 - 0.076 13.0 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, FtsQ-type SnoaL_2 PF12680.2 OAJ07410.1 - 0.00051 20.3 0.2 0.0083 16.5 0.0 2.5 2 1 0 2 2 2 1 SnoaL-like domain DUF3669 PF12417.3 OAJ07410.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger protein zf-C2H2 PF00096.21 OAJ07411.1 - 9.7e-07 28.7 2.3 0.0057 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ07411.1 - 0.00087 19.4 1.9 0.1 12.9 0.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger RNA_pol_3_Rpc31 PF11705.3 OAJ07411.1 - 0.19 11.6 23.1 0.88 9.4 16.0 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 OAJ07411.1 - 0.65 9.4 7.9 1.7 8.0 5.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.7 OAJ07411.1 - 4.7 6.3 17.7 2 7.5 8.3 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 OAJ07411.1 - 6 4.6 20.0 0.092 10.6 9.0 1.4 2 0 0 2 2 2 0 Nop14-like family NTF2 PF02136.15 OAJ07413.1 - 4.7e-11 43.0 0.0 7.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain ThiF PF00899.16 OAJ07414.1 - 2.8e-40 137.2 0.0 1.3e-39 135.1 0.0 2.1 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 OAJ07414.1 - 1.2e-26 92.0 0.1 2.5e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 OAJ07414.1 - 1.5e-21 75.5 2.4 2.8e-21 74.6 1.7 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 OAJ07414.1 - 1.3e-05 25.2 0.4 0.00031 20.7 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 OAJ07414.1 - 0.00066 19.7 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 OAJ07414.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding BSD PF03909.12 OAJ07414.1 - 0.09 12.5 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 BSD domain SNARE PF05739.14 OAJ07415.1 - 1e-16 60.3 0.8 1e-16 60.3 0.5 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 OAJ07415.1 - 4.7e-11 42.6 4.3 5.8e-11 42.3 1.5 2.1 2 1 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.16 OAJ07415.1 - 0.019 14.4 1.1 0.019 14.4 0.8 2.0 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 OAJ07415.1 - 0.99 9.6 5.9 0.36 11.0 0.9 2.5 2 1 0 2 2 2 0 Syntaxin Arrestin_C PF02752.17 OAJ07417.1 - 2.3e-05 24.5 0.0 6.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 OAJ07417.1 - 0.00031 20.6 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain EF-hand_1 PF00036.27 OAJ07419.1 - 4e-42 138.3 13.5 2.1e-10 39.0 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 OAJ07419.1 - 2.1e-37 127.0 3.7 1.4e-20 73.1 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 OAJ07419.1 - 1.8e-33 113.9 10.7 4e-16 58.3 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 OAJ07419.1 - 9.4e-32 106.0 7.2 1.3e-09 37.1 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 OAJ07419.1 - 1.4e-28 96.9 7.5 3.4e-07 29.2 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 OAJ07419.1 - 4.7e-15 55.2 0.1 2.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 OAJ07419.1 - 1.4e-09 37.5 1.2 2.9e-05 23.7 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 OAJ07419.1 - 5.3e-09 36.1 0.0 0.00038 20.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 OAJ07419.1 - 4.7e-08 32.5 1.5 0.018 14.6 0.0 3.9 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 OAJ07419.1 - 8.7e-06 25.6 1.0 4.6e-05 23.2 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 OAJ07419.1 - 0.0003 20.7 1.0 0.0017 18.2 0.2 2.3 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1103 PF06513.6 OAJ07419.1 - 0.00088 18.7 2.1 0.0011 18.4 1.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 OAJ07419.1 - 0.0016 18.0 0.1 0.26 10.8 0.0 2.6 1 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 OAJ07419.1 - 0.0028 17.3 0.2 0.94 9.2 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TerB MotA_activ PF09114.5 OAJ07419.1 - 0.019 14.7 0.3 3.1 7.6 0.1 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 OAJ07419.1 - 0.021 14.5 0.2 3.9 7.2 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein Tenui_NCP PF04876.7 OAJ07419.1 - 0.056 12.9 0.1 1.1 8.8 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 OAJ07419.1 - 0.056 13.4 1.1 6.1 6.8 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 Toprim_2 PF13155.1 OAJ07419.1 - 0.059 13.7 1.5 18 5.7 0.1 2.9 1 1 2 3 3 3 0 Toprim-like LNS2 PF08235.8 OAJ07419.1 - 0.069 12.7 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) SapB_1 PF05184.10 OAJ07419.1 - 0.1 12.4 0.1 36 4.3 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 VCBS PF13517.1 OAJ07419.1 - 3.6 8.0 6.3 18 5.7 0.3 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Sel1 PF08238.7 OAJ07420.1 - 4.8e-39 131.9 26.5 1.6e-08 34.9 0.4 9.5 8 1 1 9 9 9 7 Sel1 repeat HLH PF00010.21 OAJ07421.1 - 1.5e-14 53.4 6.2 1.7e-09 37.2 0.3 3.1 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain Daxx PF03344.10 OAJ07421.1 - 1.2 7.5 21.2 2.9 6.2 14.7 1.8 1 0 0 1 1 1 0 Daxx Family ELO PF01151.13 OAJ07422.1 - 8.2e-58 195.6 3.8 1.1e-57 195.2 2.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family NatB_MDM20 PF09797.4 OAJ07423.1 - 6.7e-52 176.4 0.1 1.1e-51 175.6 0.1 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Baculo_PEP_C PF04513.7 OAJ07423.1 - 0.036 13.8 1.0 19 5.0 0.1 3.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MoCF_biosynth PF00994.19 OAJ07424.1 - 4.6e-35 120.1 0.0 7.3e-35 119.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain MaoC_dehydratas PF01575.14 OAJ07425.1 - 9.3e-24 83.1 0.0 2.7e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 OAJ07425.1 - 3.6e-06 26.7 0.0 5.4e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Vfa1 PF08432.5 OAJ07426.1 - 3e-31 108.8 0.0 3.9e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SseC PF04888.7 OAJ07426.1 - 0.002 17.5 6.4 0.0031 16.9 4.5 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family ELL PF10390.4 OAJ07426.1 - 0.018 14.3 1.6 0.023 13.9 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL FKBP_N PF01346.13 OAJ07426.1 - 0.039 14.0 2.7 0.065 13.2 1.9 1.3 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Herpes_capsid PF06112.6 OAJ07426.1 - 1.2 9.1 7.8 2.2 8.3 5.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Activator-TraM PF11657.3 OAJ07426.1 - 1.6 8.1 6.0 2.7 7.4 4.2 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Saccharop_dh PF03435.13 OAJ07427.1 - 3.1e-22 79.0 0.0 4.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 OAJ07427.1 - 6.9e-08 32.2 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ07427.1 - 1.1e-06 28.7 0.1 4.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 OAJ07427.1 - 0.00012 20.8 0.0 0.00018 20.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 OAJ07427.1 - 0.00021 21.2 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 OAJ07427.1 - 0.00028 20.2 0.1 0.00043 19.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 OAJ07427.1 - 0.00085 19.0 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 OAJ07427.1 - 0.0051 16.9 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 OAJ07427.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 OAJ07427.1 - 0.021 13.7 0.1 0.12 11.2 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 OAJ07427.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 OAJ07428.1 - 6.2e-10 38.5 9.1 0.0037 17.0 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Senescence_reg PF04520.8 OAJ07428.1 - 0.0055 17.2 0.1 0.0094 16.4 0.1 1.4 1 0 0 1 1 1 1 Senescence regulator Coprogen_oxidas PF01218.13 OAJ07429.1 - 3.8e-112 373.6 0.8 5.6e-70 235.2 0.0 3.4 2 2 0 2 2 2 2 Coproporphyrinogen III oxidase HHH PF00633.18 OAJ07430.1 - 0.00012 21.5 0.4 0.00079 18.9 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif Transposase_20 PF02371.11 OAJ07430.1 - 0.087 12.9 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family PsbU PF06514.6 OAJ07430.1 - 0.13 12.1 0.0 9.2 6.1 0.0 2.8 1 1 1 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) TRAPPC-Trs85 PF12739.2 OAJ07431.1 - 7.5e-93 311.4 2.2 1.2e-92 310.7 1.5 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 OAJ07431.1 - 0.0033 14.8 0.0 0.0077 13.6 0.0 1.5 2 0 0 2 2 2 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 OAJ07431.1 - 0.0096 15.9 0.0 0.32 11.0 0.0 2.7 2 1 0 2 2 2 1 CARDB Malic_M PF03949.10 OAJ07432.1 - 5.9e-85 284.8 0.0 7.8e-85 284.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 OAJ07432.1 - 1.7e-63 213.4 0.0 2.6e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ATP_bind_1 PF03029.12 OAJ07433.1 - 6.9e-81 271.2 0.0 1.2e-79 267.2 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 OAJ07433.1 - 2.5e-06 27.0 0.0 6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 OAJ07433.1 - 7.1e-05 23.6 0.1 0.00029 21.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 OAJ07433.1 - 0.0006 19.3 0.0 0.0016 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 OAJ07433.1 - 0.0012 18.9 0.3 0.021 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 OAJ07433.1 - 0.0036 17.1 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 OAJ07433.1 - 0.0041 16.6 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 OAJ07433.1 - 0.005 16.8 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 OAJ07433.1 - 0.007 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 OAJ07433.1 - 0.0092 15.5 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 OAJ07433.1 - 0.014 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 OAJ07433.1 - 0.015 14.4 0.0 0.041 13.0 0.0 1.7 1 1 0 1 1 1 0 KaiC MMR_HSR1 PF01926.18 OAJ07433.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 OAJ07433.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.22 OAJ07433.1 - 0.029 13.8 0.0 0.3 10.4 0.0 2.3 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 OAJ07433.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 OAJ07433.1 - 0.04 13.8 0.1 0.19 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 OAJ07433.1 - 0.045 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 OAJ07433.1 - 0.045 13.9 0.0 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 OAJ07433.1 - 0.081 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 OAJ07433.1 - 0.088 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 OAJ07433.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.6 1 1 0 1 1 1 0 ABC transporter CobU PF02283.11 OAJ07433.1 - 0.16 11.4 0.1 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase SKG6 PF08693.5 OAJ07434.1 - 2e-09 36.5 1.0 2e-09 36.5 0.7 2.2 2 0 0 2 2 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 OAJ07434.1 - 0.00038 19.9 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 OAJ07434.1 - 0.00081 19.1 0.1 0.0021 17.7 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF1183 PF06682.7 OAJ07434.1 - 0.002 17.8 5.4 0.002 17.8 3.7 3.3 3 1 1 4 4 3 1 Protein of unknown function (DUF1183) DUF912 PF06024.7 OAJ07434.1 - 0.011 15.7 0.1 0.038 14.0 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 OAJ07434.1 - 0.014 13.6 0.0 0.033 12.4 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 OAJ07434.1 - 0.02 14.4 1.9 0.057 12.9 1.3 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF202 PF02656.10 OAJ07434.1 - 0.033 14.4 0.6 3.2 8.0 0.1 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF202) DAG1 PF05454.6 OAJ07434.1 - 0.034 13.3 0.7 0.073 12.2 0.0 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Rifin_STEVOR PF02009.11 OAJ07434.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF533 PF04391.7 OAJ07434.1 - 0.15 11.3 6.6 0.52 9.6 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF533) EphA2_TM PF14575.1 OAJ07434.1 - 0.16 12.3 0.0 0.77 10.1 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SCF PF02404.10 OAJ07434.1 - 0.32 10.1 1.1 0.51 9.4 0.8 1.2 1 0 0 1 1 1 0 Stem cell factor DUF515 PF04415.7 OAJ07434.1 - 0.5 8.5 0.5 1 7.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sedlin_N PF04628.8 OAJ07435.1 - 1.3e-28 99.4 0.0 1.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region MFS_1 PF07690.11 OAJ07436.1 - 4.2e-28 98.0 31.6 8e-28 97.1 20.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2157 PF09925.4 OAJ07436.1 - 0.0057 16.2 2.7 0.0057 16.2 1.8 3.7 4 0 0 4 4 4 1 Predicted membrane protein (DUF2157) Aconitase PF00330.15 OAJ07437.1 - 2.7e-72 243.7 0.0 3.7e-47 160.8 0.0 3.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 OAJ07437.1 - 2.1e-20 73.1 0.0 4.3e-20 72.1 0.0 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain BC10 PF06726.7 OAJ07438.1 - 1.1e-11 44.5 10.4 2e-11 43.7 7.2 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DivIVA PF05103.8 OAJ07438.1 - 0.58 10.2 7.6 1 9.4 5.2 1.3 1 0 0 1 1 1 0 DivIVA protein SWIB PF02201.13 OAJ07439.1 - 3.3e-27 93.9 0.0 5.1e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 OAJ07439.1 - 2.5e-06 27.1 1.2 8e-05 22.3 0.3 2.8 3 0 0 3 3 3 1 DEK C terminal domain Med3 PF11593.3 OAJ07439.1 - 7.2 5.7 8.3 10 5.2 5.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LSM PF01423.17 OAJ07440.1 - 5.4e-16 57.9 0.1 8.1e-16 57.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF1289 PF06945.8 OAJ07441.1 - 0.63 9.5 4.4 0.75 9.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF2256 PF10013.4 OAJ07441.1 - 8.3 6.2 7.1 6.1 6.6 1.3 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_clus PF00172.13 OAJ07442.1 - 0.0006 19.6 15.4 0.0011 18.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 OAJ07444.1 - 1.2e-14 53.5 8.7 0.00017 21.3 0.1 8.7 9 0 0 9 9 9 3 WD domain, G-beta repeat GST_N PF02798.15 OAJ07444.1 - 0.19 11.9 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain ATG27 PF09451.5 OAJ07444.1 - 6.9 5.8 5.7 14 4.7 0.2 2.2 2 0 0 2 2 2 0 Autophagy-related protein 27 AA_kinase PF00696.23 OAJ07445.1 - 2.8e-39 135.1 0.6 3.3e-39 134.8 0.4 1.1 1 0 0 1 1 1 1 Amino acid kinase family CBS PF00571.23 OAJ07445.1 - 0.064 13.0 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 0 CBS domain SoxE PF06525.6 OAJ07446.1 - 2.2 7.5 6.2 2.8 7.2 4.0 1.6 1 1 0 1 1 1 0 Sulfocyanin (SoxE) PBP1_TM PF14812.1 OAJ07448.1 - 0.21 11.9 1.2 0.65 10.3 0.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAF1A PF12253.3 OAJ07449.1 - 1.4e-21 76.4 10.3 1.4e-21 76.4 7.2 3.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Dynamin_N PF00350.18 OAJ07450.1 - 4.1e-41 140.5 0.0 8.5e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 OAJ07450.1 - 1.1e-05 24.4 0.0 3.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 OAJ07450.1 - 0.002 18.0 0.0 0.0066 16.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 OAJ07450.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 OAJ07450.1 - 0.18 11.2 0.1 15 4.9 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.1 OAJ07450.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Vps52 PF04129.7 OAJ07451.1 - 1.9e-40 138.8 0.0 7.6e-39 133.5 0.0 2.2 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.4 OAJ07451.1 - 2.2e-05 22.8 0.0 3.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Myc_N PF01056.13 OAJ07451.1 - 0.07 12.2 2.0 0.16 11.1 1.4 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 OAJ07451.1 - 0.35 9.3 3.7 0.59 8.5 2.6 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 OAJ07451.1 - 1.2 8.7 6.2 2.7 7.5 4.3 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2388 PF09498.5 OAJ07451.1 - 3.1 7.4 6.9 0.14 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Nucleoplasmin PF03066.10 OAJ07451.1 - 3.7 7.0 11.0 6.2 6.3 7.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin zf-MYND PF01753.13 OAJ07452.1 - 6.6e-11 41.9 10.4 6.6e-11 41.9 7.2 2.9 2 1 0 2 2 2 1 MYND finger SET PF00856.23 OAJ07452.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 SET domain zf-Mss51 PF13824.1 OAJ07452.1 - 0.0045 16.8 10.7 0.0066 16.2 2.7 3.2 3 0 0 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 Cyt-b5 PF00173.23 OAJ07453.1 - 2.8e-23 81.5 0.2 3e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 OAJ07453.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 V-ATPase subunit H La PF05383.12 OAJ07454.1 - 8.7e-12 44.6 0.4 1.8e-05 24.4 0.3 2.7 3 0 0 3 3 3 2 La domain RRM_1 PF00076.17 OAJ07454.1 - 1.1e-05 24.9 0.2 2.7e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ07454.1 - 4.2e-05 23.4 0.0 9.8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ07454.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 OAJ07454.1 - 0.065 13.0 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif HlyIII PF03006.15 OAJ07455.1 - 9.1e-49 165.8 21.9 1.2e-48 165.4 15.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.1 OAJ07455.1 - 0.71 9.1 9.0 0.23 10.7 3.8 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein AA_permease_2 PF13520.1 OAJ07456.1 - 2.7e-62 210.6 42.2 3.3e-62 210.3 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 OAJ07456.1 - 8.6e-30 103.4 38.0 1.4e-29 102.8 26.4 1.3 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 OAJ07457.1 - 3.8e-54 183.5 0.1 4.7e-34 117.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07457.1 - 3.1e-23 82.1 0.2 9.3e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 OAJ07457.1 - 0.037 12.9 0.0 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like HEAT_PBS PF03130.11 OAJ07457.1 - 0.046 14.1 0.0 0.19 12.2 0.0 2.1 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat APH PF01636.18 OAJ07457.1 - 0.058 13.1 0.1 0.058 13.1 0.1 3.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family DnaJ PF00226.26 OAJ07459.1 - 2.7e-19 68.6 0.1 2.7e-19 68.6 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain Wbp11 PF09429.5 OAJ07460.1 - 0.46 10.4 8.2 0.96 9.4 0.7 2.7 2 1 1 3 3 3 0 WW domain binding protein 11 Semialdhyde_dhC PF02774.13 OAJ07461.1 - 1.4e-42 145.5 0.0 2.9e-42 144.6 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 OAJ07461.1 - 1.3e-29 102.9 0.0 2.6e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 OAJ07461.1 - 0.003 17.4 0.0 0.0076 16.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 OAJ07461.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GATA PF00320.22 OAJ07462.1 - 4.5e-17 61.0 4.6 9.9e-17 60.0 3.2 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 OAJ07462.1 - 2.3e-14 52.6 2.2 4.2e-14 51.8 1.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PC_rep PF01851.17 OAJ07463.1 - 1.3e-18 66.1 21.7 0.0014 18.7 0.0 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat Pyr_redox_2 PF07992.9 OAJ07464.1 - 6e-29 101.3 0.1 7.4e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ07464.1 - 3.3e-17 62.6 0.0 2.1e-14 53.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 OAJ07464.1 - 3.5e-07 30.4 0.1 0.0036 17.3 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 OAJ07464.1 - 4.2e-06 26.0 0.1 8.5e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 OAJ07464.1 - 5.9e-06 25.6 0.0 0.033 13.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 OAJ07464.1 - 0.00012 21.1 1.5 0.0051 15.7 0.1 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ07464.1 - 0.00021 20.4 0.1 0.034 13.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 OAJ07464.1 - 0.00025 20.0 1.3 0.0048 15.7 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAJ07464.1 - 0.00041 19.3 1.0 0.0047 15.8 0.0 2.5 1 1 2 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 OAJ07464.1 - 0.00082 19.3 0.2 0.0095 15.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 OAJ07464.1 - 0.00091 19.4 0.2 0.052 13.8 0.0 2.7 3 1 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 OAJ07464.1 - 0.001 19.1 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 OAJ07464.1 - 0.0039 15.8 0.1 0.051 12.2 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 OAJ07464.1 - 0.0069 14.8 0.1 0.03 12.7 0.1 2.0 1 1 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 OAJ07464.1 - 0.0092 14.9 0.0 0.48 9.2 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) zf-Tim10_DDP PF02953.10 OAJ07465.1 - 1.2e-18 66.1 2.5 1.5e-18 65.8 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger FANCI_S3 PF14677.1 OAJ07465.1 - 0.068 12.5 0.3 0.082 12.2 0.2 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 FTR PF01913.13 OAJ07465.1 - 0.072 12.8 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Ins_beta PF03488.9 OAJ07465.1 - 0.085 12.6 0.5 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Aminotran_1_2 PF00155.16 OAJ07466.1 - 3.4e-50 171.0 0.0 6.4e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 OAJ07466.1 - 8.9e-06 25.3 1.7 0.046 13.6 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat BUD22 PF09073.5 OAJ07466.1 - 0.031 13.3 4.2 0.048 12.7 2.9 1.2 1 0 0 1 1 1 0 BUD22 WD40 PF00400.27 OAJ07467.1 - 1.8e-15 56.1 9.4 8e-06 25.5 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat FAD_binding_4 PF01565.18 OAJ07469.1 - 5.5e-15 55.0 1.2 9.9e-15 54.2 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 OAJ07469.1 - 1.4e-08 34.5 0.2 3.3e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ArfGap PF01412.13 OAJ07470.1 - 2.9e-32 110.9 0.3 5.3e-32 110.0 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 OAJ07470.1 - 4.2e-09 36.5 0.0 7.2e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 PH domain Nfu_N PF08712.6 OAJ07471.1 - 4.8e-33 112.6 0.0 1.3e-32 111.2 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 OAJ07471.1 - 8.7e-16 57.4 0.4 2.1e-14 53.0 0.1 2.3 1 1 0 2 2 2 1 NifU-like domain RVT_2 PF07727.9 OAJ07472.1 - 2.5e-87 291.9 0.0 3.4e-87 291.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07472.1 - 9.6e-27 93.4 0.0 2.7e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DnaJ PF00226.26 OAJ07472.1 - 2.4e-23 81.6 0.6 4.5e-23 80.7 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Methyltransf_6 PF03737.10 OAJ07472.1 - 8e-23 81.0 0.1 1.9e-18 66.8 0.0 2.4 2 0 0 2 2 2 2 Demethylmenaquinone methyltransferase CTDII PF01556.13 OAJ07472.1 - 5.8e-19 67.7 0.0 7.5e-15 54.5 0.0 2.7 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 OAJ07472.1 - 5e-14 52.1 17.7 1.1e-13 50.9 12.3 1.6 1 0 0 1 1 1 1 DnaJ central domain gag_pre-integrs PF13976.1 OAJ07472.1 - 1.7e-06 27.5 0.2 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 OAJ07472.1 - 4.6e-05 22.8 0.0 0.00013 21.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Cytochrom_c3_2 PF14537.1 OAJ07472.1 - 1.2 9.5 5.5 2.9 8.3 3.8 1.7 1 0 0 1 1 1 0 Cytochrome c3 HCNGP PF07818.8 OAJ07473.1 - 6.1e-15 55.0 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 HCNGP-like protein Glycos_transf_2 PF00535.21 OAJ07474.1 - 4.7e-30 104.4 0.0 6.1e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 OAJ07474.1 - 2.2e-14 53.8 0.0 3.9e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 OAJ07474.1 - 1.8e-06 27.2 0.0 2.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 OAJ07474.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 OAJ07474.1 - 0.0099 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 OAJ07474.1 - 0.033 14.4 0.0 0.066 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_7N PF13733.1 OAJ07474.1 - 0.086 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 Dus PF01207.12 OAJ07483.1 - 3.5e-48 164.0 0.0 5.7e-48 163.3 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) 4HBT_3 PF13622.1 OAJ07484.1 - 4.1e-41 141.4 0.3 1.2e-40 139.9 0.2 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 OAJ07484.1 - 9.8e-22 76.9 0.0 4e-18 65.2 0.0 2.6 2 1 0 2 2 2 2 Acyl-CoA thioesterase W2 PF02020.13 OAJ07487.1 - 6.3e-18 64.5 0.1 6.3e-18 64.5 0.1 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon ArfGap PF01412.13 OAJ07488.1 - 4.3e-35 120.0 2.1 6.2e-31 106.6 0.1 2.2 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf zf-Nse PF11789.3 OAJ07490.1 - 1e-13 50.5 0.1 2.1e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 OAJ07490.1 - 0.002 18.0 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.1 OAJ07490.1 - 0.033 13.8 0.1 0.085 12.5 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF3213 PF11491.3 OAJ07490.1 - 0.18 11.6 1.0 0.43 10.4 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3213) PEPCK_ATP PF01293.15 OAJ07492.1 - 2.1e-214 712.3 0.0 2.5e-214 712.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 OAJ07492.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 OAJ07492.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAPP PF04051.11 OAJ07493.1 - 2e-31 108.5 0.0 2.6e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Methyltransf_18 PF12847.2 OAJ07494.1 - 3.3e-11 43.7 0.0 6.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ07494.1 - 1.5e-09 37.7 0.0 3.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ07494.1 - 3.1e-06 26.8 0.1 6.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 OAJ07494.1 - 2.4e-05 23.9 0.1 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 OAJ07494.1 - 0.001 19.4 0.0 0.0041 17.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ07494.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ07494.1 - 0.0075 17.0 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 OAJ07494.1 - 0.0086 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 OAJ07494.1 - 0.013 14.8 0.0 0.04 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 OAJ07494.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 OAJ07494.1 - 0.018 15.5 0.1 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ07494.1 - 0.023 15.0 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_3 PF01596.12 OAJ07494.1 - 0.028 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_9 PF08003.6 OAJ07494.1 - 0.046 12.4 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 OAJ07494.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PAS PF00989.19 OAJ07495.1 - 0.00024 20.8 0.0 0.00096 18.9 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 OAJ07495.1 - 0.00025 21.3 0.0 0.00074 19.8 0.0 1.7 2 0 0 2 2 2 1 PAS domain Zn_clus PF00172.13 OAJ07495.1 - 0.00038 20.2 10.9 0.00038 20.2 7.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG_box PF00505.14 OAJ07496.1 - 7.4e-13 48.5 2.7 3.7e-09 36.7 0.5 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ07496.1 - 0.00017 21.8 1.9 0.00017 21.8 1.3 2.6 2 1 0 2 2 2 1 HMG-box domain TFIIIC_delta PF12657.2 OAJ07497.1 - 4.4e-19 68.8 1.7 7.4e-19 68.1 0.4 2.0 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term HSF_DNA-bind PF00447.12 OAJ07498.1 - 4.8e-31 107.0 0.3 7e-31 106.4 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Nucleoplasmin PF03066.10 OAJ07498.1 - 0.05 13.1 1.6 0.089 12.3 1.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin PUL PF08324.6 OAJ07498.1 - 0.11 11.2 0.3 0.54 9.0 0.1 1.9 2 0 0 2 2 2 0 PUL domain Daxx PF03344.10 OAJ07498.1 - 0.13 10.6 9.2 0.46 8.9 0.1 2.2 2 0 0 2 2 2 0 Daxx Family Sigma70_ner PF04546.8 OAJ07498.1 - 0.33 10.5 1.7 0.51 9.9 0.6 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 OAJ07498.1 - 9.1 6.5 10.2 23 5.3 7.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MARVEL PF01284.18 OAJ07499.1 - 0.044 13.6 14.9 0.18 11.6 10.1 2.2 1 1 0 1 1 1 0 Membrane-associating domain Dimerisation PF08100.6 OAJ07501.1 - 0.04 13.7 0.2 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 Dimerisation domain K_oxygenase PF13434.1 OAJ07503.1 - 2.2e-87 293.1 0.0 4.8e-87 292.0 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 OAJ07503.1 - 1.8e-09 37.5 0.0 6.5e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 OAJ07503.1 - 2.6e-06 27.6 0.0 5.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 OAJ07503.1 - 0.16 12.3 0.0 0.47 10.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EBP PF05241.7 OAJ07504.1 - 1.7e-06 27.1 4.7 3e-06 26.3 3.3 1.4 1 1 0 1 1 1 1 Emopamil binding protein eIF2A PF08662.6 OAJ07505.1 - 6.7e-82 273.9 0.1 1.2e-79 266.5 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 OAJ07505.1 - 0.0022 17.8 0.4 0.6 10.0 0.1 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 OAJ07505.1 - 0.019 15.0 2.0 0.019 15.0 1.4 3.5 3 1 1 4 4 4 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.4 OAJ07505.1 - 0.83 9.0 3.2 33 3.9 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature TrkH PF02386.11 OAJ07506.1 - 1.6e-88 296.6 10.9 1.8e-85 286.6 3.5 2.1 2 0 0 2 2 2 2 Cation transport protein TrkH PF02386.11 OAJ07507.1 - 3.1e-87 292.4 14.3 3.7e-86 288.8 1.2 2.1 2 0 0 2 2 2 2 Cation transport protein UPF0016 PF01169.14 OAJ07508.1 - 9.5e-43 144.2 27.6 2.1e-22 79.0 5.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.26 OAJ07508.1 - 0.00018 20.8 2.2 0.00018 20.8 1.5 1.5 2 1 0 2 2 2 1 Ion transport protein DUF308 PF03729.8 OAJ07508.1 - 0.071 13.1 0.5 0.071 13.1 0.4 3.2 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) DUF2678 PF10856.3 OAJ07508.1 - 0.19 11.4 2.2 0.22 11.2 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Fis1_TPR_C PF14853.1 OAJ07509.1 - 5.8e-24 83.7 0.3 8.9e-24 83.1 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 OAJ07509.1 - 1.5e-13 49.7 0.0 3.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 OAJ07509.1 - 0.00099 18.8 0.7 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ07509.1 - 0.012 16.3 0.2 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 OAJ07509.1 - 0.028 14.8 1.9 17 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ07509.1 - 0.048 14.3 0.9 0.75 10.6 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ07509.1 - 0.073 13.4 0.5 0.67 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ESCRT-II PF05871.7 OAJ07510.1 - 4.2e-46 156.3 0.0 1.3e-45 154.7 0.0 1.7 1 1 1 2 2 2 1 ESCRT-II complex subunit FeoC PF09012.5 OAJ07510.1 - 0.1 12.2 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator APC_CDC26 PF10471.4 OAJ07511.1 - 5.1e-07 30.3 10.1 1.7e-06 28.6 7.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 MHYT PF03707.11 OAJ07512.1 - 3.3e-13 49.5 16.5 2.4e-06 27.5 0.9 4.7 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat Pkinase PF00069.20 OAJ07513.1 - 2.1e-57 194.2 0.0 2.6e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07513.1 - 3.1e-20 72.3 0.0 4.3e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 OAJ07513.1 - 2.8e-07 30.5 0.4 1.7e-05 24.6 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 OAJ07513.1 - 0.0077 15.8 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 OAJ07513.1 - 0.017 14.2 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 OAJ07513.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like F-box-like PF12937.2 OAJ07514.1 - 1.2e-05 24.8 0.1 5.8e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ07514.1 - 0.00018 21.0 0.0 0.0024 17.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain Foamy_BEL PF03274.9 OAJ07514.1 - 0.039 13.1 0.8 5 6.2 0.0 2.3 2 0 0 2 2 2 0 Foamy virus BEL 1/2 protein Pro_isomerase PF00160.16 OAJ07515.1 - 6.7e-45 153.0 0.6 1.1e-44 152.3 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4366 PF14283.1 OAJ07515.1 - 0.0028 17.1 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) ABC_membrane PF00664.18 OAJ07516.1 - 1.3e-81 274.0 25.5 5.1e-42 144.1 3.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ07516.1 - 4.1e-62 208.5 0.0 2.7e-31 108.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 OAJ07516.1 - 5.6e-13 48.6 0.6 5.4e-05 22.5 0.0 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 OAJ07516.1 - 2e-07 31.0 0.1 0.0048 16.7 0.0 3.4 4 0 0 4 4 4 2 Domain of unknown function DUF87 AAA_17 PF13207.1 OAJ07516.1 - 6e-07 30.2 0.0 0.044 14.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 OAJ07516.1 - 6.6e-07 28.7 0.1 0.03 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 OAJ07516.1 - 4.9e-06 26.7 0.0 0.65 9.9 0.0 4.3 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 OAJ07516.1 - 2.3e-05 24.5 0.1 10 6.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.1 OAJ07516.1 - 4.3e-05 23.3 0.4 0.32 10.9 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 OAJ07516.1 - 4.6e-05 22.1 0.1 0.059 11.9 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 OAJ07516.1 - 0.0002 21.4 4.1 0.27 11.2 0.1 4.0 3 2 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.1 OAJ07516.1 - 0.00041 20.6 0.0 1.2 9.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain PRK PF00485.13 OAJ07516.1 - 0.00047 19.7 0.1 0.87 9.1 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 OAJ07516.1 - 0.00052 19.5 1.7 4.9 6.5 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 OAJ07516.1 - 0.00069 18.7 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 OAJ07516.1 - 0.00084 18.8 0.0 0.16 11.4 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 OAJ07516.1 - 0.00097 19.0 0.7 2.9 7.7 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 OAJ07516.1 - 0.001 18.7 0.1 0.74 9.3 0.0 3.9 5 0 0 5 5 4 1 AAA domain DUF258 PF03193.11 OAJ07516.1 - 0.0014 17.8 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 OAJ07516.1 - 0.0031 16.9 0.2 3.7 6.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 OAJ07516.1 - 0.0058 16.3 0.2 4 7.1 0.0 2.8 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 OAJ07516.1 - 0.0075 15.0 0.6 2.1 6.9 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit APS_kinase PF01583.15 OAJ07516.1 - 0.012 15.2 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 OAJ07516.1 - 0.13 12.5 0.2 24 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Alpha-amylase_C PF02806.13 OAJ07517.1 - 4.6e-27 94.0 0.1 1.3e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 OAJ07517.1 - 2.2e-18 66.7 0.0 6.7e-14 51.9 0.0 2.9 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 OAJ07517.1 - 8.6e-13 48.1 0.2 2.3e-12 46.7 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 OAJ07517.1 - 0.047 12.0 0.0 0.079 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 GHL6 PF14871.1 OAJ07517.1 - 0.094 12.7 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 PI3_PI4_kinase PF00454.22 OAJ07518.1 - 1.2e-32 113.2 0.0 1.9e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Histone PF00125.19 OAJ07520.1 - 8.7e-26 89.8 0.2 1.3e-25 89.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 OAJ07520.1 - 2e-05 24.6 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 OAJ07520.1 - 0.00056 19.2 0.0 0.00069 18.9 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 OAJ07520.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 OAJ07520.1 - 0.035 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MIR PF02815.14 OAJ07522.1 - 1.8e-05 24.3 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain Transposase_21 PF02992.9 OAJ07523.1 - 1.8e-21 76.2 0.0 3.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 OAJ07523.1 - 0.0012 18.3 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) E1_dh PF00676.15 OAJ07524.1 - 2.4e-82 276.0 0.0 3e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 OAJ07524.1 - 0.00017 20.5 0.0 0.00038 19.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 OAJ07524.1 - 0.052 12.4 0.0 0.18 10.6 0.0 1.8 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase PLU-1 PF08429.6 OAJ07525.1 - 2.2e-47 161.5 4.7 3.5e-47 160.9 3.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 OAJ07525.1 - 2.9e-42 143.5 0.2 6.5e-42 142.3 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 OAJ07525.1 - 4.1e-21 74.4 44.2 1.4e-12 47.0 2.1 4.2 4 0 0 4 4 4 3 PHD-finger ARID PF01388.16 OAJ07525.1 - 4.6e-20 71.2 0.0 8.7e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.11 OAJ07525.1 - 1.5e-12 47.3 0.6 4.9e-12 45.7 0.4 2.0 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 OAJ07525.1 - 3.3e-12 45.7 0.8 6.9e-12 44.6 0.6 1.6 1 0 0 1 1 1 1 jmjN domain DUF1310 PF07006.6 OAJ07525.1 - 2.3 7.7 0.0 4.4 6.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) Prok-RING_1 PF14446.1 OAJ07525.1 - 3.5 7.4 25.6 2.8 7.7 4.2 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Reo_sigmaC PF04582.7 OAJ07526.1 - 0.067 12.3 3.2 0.15 11.2 0.6 2.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 OAJ07526.1 - 0.21 11.3 19.3 1.6 8.4 3.2 3.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 OAJ07526.1 - 0.22 10.1 11.0 0.011 14.4 2.3 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 OAJ07526.1 - 0.36 9.9 19.3 0.4 9.8 5.7 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.3 OAJ07526.1 - 1.6 7.9 13.9 1.1 8.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) IncA PF04156.9 OAJ07526.1 - 1.6 8.2 22.4 3.1 7.3 5.2 3.4 2 1 1 3 3 3 0 IncA protein Seryl_tRNA_N PF02403.17 OAJ07526.1 - 1.7 8.7 15.9 0.12 12.4 2.0 3.7 3 2 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_L29 PF00831.18 OAJ07526.1 - 2.3 7.9 12.6 3.3 7.4 0.1 3.8 3 0 0 3 3 3 0 Ribosomal L29 protein Spc24 PF08286.6 OAJ07527.1 - 0.06 13.0 1.9 0.15 11.7 1.3 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 CIDE-N PF02017.10 OAJ07527.1 - 0.075 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 CIDE-N domain CoA_transf_3 PF02515.12 OAJ07528.1 - 4.2e-46 156.5 0.0 6.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III TPR_11 PF13414.1 OAJ07529.1 - 1.2e-23 82.4 17.9 7.3e-12 44.7 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 OAJ07529.1 - 8.2e-21 72.6 1.0 7.8e-07 28.4 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ07529.1 - 4.8e-20 69.7 10.2 1.9e-05 24.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ07529.1 - 5.2e-13 48.3 7.9 0.0066 16.9 0.7 5.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ07529.1 - 3.1e-12 46.8 5.3 9.7e-08 32.4 0.1 4.9 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ07529.1 - 1.4e-11 43.3 0.1 0.046 13.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ07529.1 - 3.1e-11 42.5 3.1 0.00012 21.9 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ07529.1 - 5.1e-10 39.5 3.2 0.0084 16.4 0.4 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ07529.1 - 4.7e-09 36.0 11.3 2e-05 24.4 1.1 4.1 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ07529.1 - 1.5e-07 30.6 1.6 0.075 12.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 OAJ07529.1 - 0.00039 20.4 7.5 0.085 12.9 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ07529.1 - 0.0026 17.6 6.3 2.4 8.2 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ07529.1 - 0.0042 17.4 12.4 5.6 7.6 0.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 OAJ07529.1 - 0.0092 16.0 0.6 0.0092 16.0 0.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 OAJ07529.1 - 0.016 15.4 12.7 0.13 12.5 1.4 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_15 PF13429.1 OAJ07529.1 - 0.033 13.2 4.6 1.3 8.0 1.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 OAJ07529.1 - 0.042 13.6 0.8 1.1 9.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 OAJ07529.1 - 0.076 12.2 0.2 0.87 8.7 0.0 2.4 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_9 PF13371.1 OAJ07529.1 - 0.2 11.5 8.1 0.23 11.3 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 OAJ07529.1 - 0.2 11.5 1.9 7.9 6.4 0.0 4.0 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain AAA_13 PF13166.1 OAJ07529.1 - 0.61 8.4 2.5 0.9 7.9 1.8 1.1 1 0 0 1 1 1 0 AAA domain ATG13 PF10033.4 OAJ07530.1 - 3.8e-27 95.2 0.0 6.1e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Nuc_sug_transp PF04142.10 OAJ07531.1 - 4.7e-52 176.5 0.6 1.4e-36 125.8 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 OAJ07531.1 - 0.00055 19.9 2.1 0.00055 19.9 1.4 3.0 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 OAJ07531.1 - 0.00074 19.7 1.1 0.00074 19.7 0.8 3.1 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 OAJ07531.1 - 0.0031 17.1 5.7 0.01 15.4 1.2 3.0 3 0 0 3 3 3 1 Triose-phosphate Transporter family OSCP PF00213.13 OAJ07532.1 - 1.3e-38 132.5 0.5 1.6e-38 132.3 0.4 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pilin PF00114.14 OAJ07532.1 - 5.3 7.8 5.8 4.8 7.9 1.1 2.1 1 1 0 2 2 2 0 Pilin (bacterial filament) PALP PF00291.20 OAJ07533.1 - 1.1e-63 215.3 0.2 1.7e-63 214.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CCCH_2 PF14608.1 OAJ07534.1 - 0.008 16.1 28.7 1.9 8.5 0.3 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type zf-C3H1 PF10650.4 OAJ07534.1 - 9.5 5.8 14.5 0.15 11.5 2.5 3.1 3 0 0 3 3 3 0 Putative zinc-finger domain Cyclin_N PF00134.18 OAJ07535.1 - 3.6e-09 36.2 0.0 6.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 OAJ07535.1 - 3.4e-07 30.7 1.2 1.2e-06 29.0 0.0 2.5 2 2 0 2 2 2 1 Cyclin GCR1_C PF12550.3 OAJ07536.1 - 9.4e-21 73.4 0.3 1.9e-20 72.4 0.2 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Methyltransf_23 PF13489.1 OAJ07537.1 - 1.1e-17 64.2 0.1 1.5e-17 63.7 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ07537.1 - 1.6e-15 57.6 0.0 3.3e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ07537.1 - 3.5e-15 56.2 0.1 1.5e-14 54.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ07537.1 - 1.6e-13 50.5 0.0 2.8e-12 46.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ07537.1 - 1.4e-12 47.8 0.0 1.2e-11 44.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ07537.1 - 9.4e-12 45.1 0.1 6e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ07537.1 - 7.1e-07 29.2 0.0 1.9e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 OAJ07537.1 - 3e-06 26.7 0.1 0.00092 18.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 OAJ07537.1 - 8e-06 25.1 0.1 4.7e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 OAJ07537.1 - 0.0027 17.1 0.1 0.047 13.0 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) TPMT PF05724.6 OAJ07537.1 - 0.0056 16.1 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 OAJ07537.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase DREV PF05219.7 OAJ07537.1 - 0.031 13.1 0.0 0.086 11.6 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase RrnaAD PF00398.15 OAJ07537.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 OAJ07537.1 - 0.098 11.3 0.0 0.62 8.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) SelP_N PF04592.9 OAJ07537.1 - 1.4 8.2 19.4 0.32 10.3 11.2 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Mito_carr PF00153.22 OAJ07538.1 - 2.8e-46 155.1 0.0 1.7e-14 53.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein LCAT PF02450.10 OAJ07539.1 - 1e-81 274.9 0.0 1.9e-81 274.0 0.0 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase CTP_transf_1 PF01148.15 OAJ07540.1 - 1.1e-11 44.8 5.7 2.3e-09 37.3 3.9 2.9 1 1 0 1 1 1 1 Cytidylyltransferase family Nup54 PF13874.1 OAJ07541.1 - 9.6e-20 70.6 4.1 7.2e-19 67.8 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 OAJ07541.1 - 6.7e-11 42.4 103.2 5e-07 29.9 31.4 4.4 2 2 1 3 3 3 2 Nucleoporin FG repeat region TFIIA PF03153.8 OAJ07541.1 - 0.11 12.3 7.5 0.19 11.6 5.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 OAJ07541.1 - 3 6.7 6.6 4.7 6.1 4.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.8 OAJ07542.1 - 5.6 6.7 6.9 6.6 6.5 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MmgE_PrpD PF03972.9 OAJ07543.1 - 2.8e-149 497.0 0.7 3.3e-149 496.8 0.5 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ERO1 PF04137.10 OAJ07544.1 - 4e-118 394.5 0.0 1.1e-116 389.7 0.0 2.1 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ATP-grasp_2 PF08442.5 OAJ07545.1 - 3.3e-69 232.3 0.2 5.6e-69 231.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 OAJ07545.1 - 9.6e-24 83.7 1.0 1.7e-23 82.8 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 OAJ07545.1 - 2.4e-12 46.5 0.4 5e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 OAJ07545.1 - 0.00081 19.0 0.1 0.0022 17.5 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 OAJ07545.1 - 0.0051 16.5 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HipA_N PF07805.7 OAJ07545.1 - 0.021 15.0 0.1 0.45 10.7 0.0 2.8 1 1 1 2 2 2 0 HipA-like N-terminal domain CPSase_L_D2 PF02786.12 OAJ07545.1 - 0.064 12.5 0.1 0.17 11.1 0.1 1.7 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 OAJ07545.1 - 0.079 12.3 0.1 0.25 10.6 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain TRAPP PF04051.11 OAJ07546.1 - 7.3e-39 132.7 0.0 1e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component ApbA PF02558.11 OAJ07547.1 - 4e-28 97.7 0.0 7e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 OAJ07547.1 - 1.8e-25 89.3 0.0 3.9e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 OAJ07547.1 - 0.0027 16.6 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 OAJ07547.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pollen_Ole_e_I PF01190.12 OAJ07547.1 - 0.15 11.9 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Pollen proteins Ole e I like Pyr_redox PF00070.22 OAJ07547.1 - 0.16 12.4 0.1 0.31 11.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.18 OAJ07548.1 - 3.1e-69 233.0 0.6 4.5e-69 232.5 0.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 OAJ07548.1 - 5.6e-16 58.6 0.6 5.6e-16 58.6 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 OAJ07548.1 - 4.2e-15 55.3 0.0 1.1e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 OAJ07548.1 - 8e-13 47.8 0.7 1.4e-08 34.2 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.10 OAJ07548.1 - 2.9e-06 27.2 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LysM PF01476.15 OAJ07549.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 LysM domain WD40 PF00400.27 OAJ07550.1 - 4.8e-23 80.1 17.2 2.5e-07 30.3 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat SBDS PF01172.13 OAJ07551.1 - 2.6e-20 71.9 0.3 3.2e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ABA_GPCR PF12430.3 OAJ07552.1 - 5.3e-34 117.0 4.7 1.1e-33 116.0 3.3 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 OAJ07552.1 - 2.7e-12 46.5 0.8 2.7e-12 46.5 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) FAD_binding_1 PF00667.15 OAJ07553.1 - 1.7e-54 184.6 0.0 3e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 OAJ07553.1 - 5.8e-33 113.9 0.1 1.2e-32 112.9 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 OAJ07553.1 - 2.7e-21 76.2 0.0 1.2e-20 74.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 OAJ07553.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain DUF1275 PF06912.6 OAJ07554.1 - 5.9e-25 87.7 12.2 7.6e-25 87.3 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PAP2 PF01569.16 OAJ07556.1 - 7.2e-11 41.8 8.1 3e-10 39.8 5.6 2.0 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 OAJ07556.1 - 3.8e-05 23.2 9.3 0.00015 21.3 6.4 2.0 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 OAJ07556.1 - 0.38 11.0 10.6 0.068 13.4 4.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal RNB PF00773.14 OAJ07557.1 - 2.9e-89 299.5 0.0 4e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 OAJ07557.1 - 1.6e-07 31.5 0.0 4.9e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 PIN domain DUF916 PF06030.7 OAJ07557.1 - 0.25 11.1 0.3 0.56 10.0 0.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) COG6 PF06419.6 OAJ07559.1 - 0.21 9.7 0.2 0.27 9.3 0.1 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 HAD PF12710.2 OAJ07560.1 - 2.3e-17 63.7 0.0 8.8e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 OAJ07560.1 - 6.7e-17 61.2 0.1 6e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 OAJ07560.1 - 4.2e-15 56.7 2.7 1.3e-10 42.0 1.7 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ07560.1 - 4e-13 49.1 0.0 1.1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 OAJ07560.1 - 0.0023 17.5 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L37ae PF01780.14 OAJ07561.1 - 5e-39 132.0 6.9 5.6e-39 131.9 4.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 OAJ07561.1 - 0.0044 16.8 2.5 0.0069 16.1 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 OAJ07561.1 - 0.0054 16.4 3.6 0.62 9.8 2.5 2.4 1 1 0 1 1 1 1 BED zinc finger Zn-ribbon_8 PF09723.5 OAJ07561.1 - 0.067 13.1 1.5 0.46 10.4 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 OAJ07561.1 - 0.077 12.7 2.6 0.12 12.0 1.8 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-FCS PF06467.9 OAJ07561.1 - 0.15 11.7 1.8 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif A2L_zn_ribbon PF08792.5 OAJ07561.1 - 0.17 11.3 3.0 0.3 10.5 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 OAJ07561.1 - 0.18 11.5 1.8 0.26 11.0 1.2 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.1 OAJ07561.1 - 0.19 12.1 5.4 0.45 10.8 0.4 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 OAJ07561.1 - 0.22 11.0 1.4 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.6 OAJ07561.1 - 0.27 10.9 4.0 0.41 10.3 2.5 1.6 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Sgf11 PF08209.6 OAJ07561.1 - 0.87 8.9 3.2 1.4 8.3 0.1 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Ribosomal_L44 PF00935.14 OAJ07561.1 - 1 9.4 6.4 3.8 7.6 1.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 Sec8_exocyst PF04048.9 OAJ07562.1 - 3.3e-33 114.2 0.1 8.8e-33 112.9 0.1 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 OAJ07562.1 - 2.6e-05 23.2 0.2 6.1e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 OAJ07562.1 - 0.00024 20.9 0.4 0.0017 18.2 0.0 2.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Bap31 PF05529.7 OAJ07563.1 - 1.8e-48 164.5 4.6 2.4e-48 164.1 3.2 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 OAJ07563.1 - 0.47 9.9 5.2 17 4.9 0.6 3.0 3 0 0 3 3 3 0 Septum formation initiator Chorein_N PF12624.2 OAJ07564.1 - 1.5e-40 137.4 0.1 4.4e-40 135.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Yae1_N PF09811.4 OAJ07573.1 - 7.5e-07 28.5 8.5 2.2e-06 27.0 5.9 1.9 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 OAJ07573.1 - 0.0033 17.0 0.3 0.34 10.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2029 PF09594.5 OAJ07574.1 - 0.0024 17.4 4.2 0.01 15.3 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Rifin_STEVOR PF02009.11 OAJ07574.1 - 0.038 13.6 0.1 3.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Rifin/stevor family DAG1 PF05454.6 OAJ07574.1 - 0.088 11.9 0.0 0.088 11.9 0.0 2.0 2 1 0 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CcmD PF04995.9 OAJ07574.1 - 0.17 11.6 1.1 0.34 10.6 0.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DEAD PF00270.24 OAJ07576.1 - 7e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07576.1 - 3.1e-08 33.3 0.4 1.7e-07 30.9 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OmpH PF03938.9 OAJ07576.1 - 0.033 14.1 7.9 0.065 13.1 5.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1682 PF07946.9 OAJ07576.1 - 9.3 4.9 14.1 17 4.1 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ras PF00071.17 OAJ07578.1 - 3.6e-45 153.2 0.0 1.2e-42 145.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 OAJ07578.1 - 9.5e-21 74.5 0.0 1.6e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ07578.1 - 1.6e-11 43.7 0.0 2.7e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ07578.1 - 6.3e-06 25.5 0.0 8.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 OAJ07578.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 OAJ07578.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit 4HBT PF03061.17 OAJ07579.1 - 2.2e-08 34.0 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily zf-RING_6 PF14835.1 OAJ07579.1 - 0.061 13.1 1.9 0.29 10.9 1.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF4442 PF14539.1 OAJ07579.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) C2 PF00168.25 OAJ07580.1 - 3.7e-11 42.7 0.0 8.9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain OKR_DC_1_N PF03709.10 OAJ07582.1 - 0.012 15.6 0.1 52 3.9 0.0 4.9 5 1 2 7 7 7 0 Orn/Lys/Arg decarboxylase, N-terminal domain RabGAP-TBC PF00566.13 OAJ07583.1 - 1.9e-18 66.7 0.0 3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PIF1 PF05970.9 OAJ07584.1 - 2.4e-192 638.6 0.0 5.3e-95 318.4 0.0 2.1 2 0 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 OAJ07584.1 - 6.4e-57 192.2 0.1 1.5e-56 191.0 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 OAJ07584.1 - 1.8e-16 60.3 0.0 8.1e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain F-box PF00646.28 OAJ07584.1 - 1.1e-07 31.3 2.2 9.2e-05 21.9 0.1 4.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 OAJ07584.1 - 1.2e-06 28.1 0.4 1.2e-06 28.1 0.3 2.4 3 0 0 3 3 3 1 F-box-like KAP_NTPase PF07693.9 OAJ07584.1 - 8e-06 25.0 0.0 0.13 11.2 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain AAA_19 PF13245.1 OAJ07584.1 - 0.00013 21.6 2.6 0.58 9.9 0.1 3.2 3 0 0 3 3 3 2 Part of AAA domain Torsin PF06309.6 OAJ07584.1 - 0.00082 19.2 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Torsin AAA_16 PF13191.1 OAJ07584.1 - 0.0015 18.5 6.0 0.86 9.5 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain T2SE PF00437.15 OAJ07584.1 - 0.018 13.9 0.2 7.5 5.3 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF2075 PF09848.4 OAJ07584.1 - 0.038 12.9 0.0 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MraZ PF02381.13 OAJ07584.1 - 0.059 13.1 0.0 22 4.9 0.0 3.0 2 0 0 2 2 2 0 MraZ protein DUF3296 PF11726.3 OAJ07584.1 - 0.22 11.0 0.0 0.53 9.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) OprD PF03573.8 OAJ07584.1 - 0.26 10.0 0.6 17 4.0 0.0 2.2 2 0 0 2 2 2 0 outer membrane porin, OprD family AAA PF00004.24 OAJ07584.1 - 0.26 11.4 0.0 43 4.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.4 OAJ07584.1 - 0.56 9.0 0.0 32 3.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 OAJ07584.1 - 0.64 8.8 0.0 36 3.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DOT1 PF08123.8 OAJ07584.1 - 0.72 9.1 0.0 45 3.2 0.0 2.2 2 0 0 2 2 2 0 Histone methylation protein DOT1 Pol_alpha_B_N PF08418.5 OAJ07585.1 - 1.4e-37 129.6 0.1 6e-37 127.5 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 OAJ07585.1 - 1.5e-28 99.4 0.4 2.4e-28 98.8 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B bZIP_1 PF00170.16 OAJ07586.1 - 9.6e-06 25.4 3.3 2.5e-05 24.1 2.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 OAJ07586.1 - 0.0023 17.7 4.2 0.0023 17.7 2.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper IncA PF04156.9 OAJ07586.1 - 3.2 7.2 14.5 7.3 6.1 0.3 2.3 2 0 0 2 2 2 0 IncA protein FimP PF09766.4 OAJ07586.1 - 9.9 5.1 16.5 0.87 8.5 7.2 1.9 2 0 0 2 2 2 0 Fms-interacting protein PARP PF00644.15 OAJ07587.1 - 6.5e-05 22.4 0.2 0.00029 20.3 0.1 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ecl1 PF12855.2 OAJ07587.1 - 9.3 5.6 8.8 31 3.9 5.5 2.3 1 1 1 2 2 2 0 Life-span regulatory factor Acyl_transf_3 PF01757.17 OAJ07589.1 - 7.1e-16 57.9 45.3 2.7e-15 56.0 31.4 2.0 1 1 0 1 1 1 1 Acyltransferase family MAP65_ASE1 PF03999.7 OAJ07591.1 - 0.068 11.7 0.5 0.12 10.8 0.3 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Apt1 PF10351.4 OAJ07592.1 - 7.8e-109 364.5 0.7 7.8e-109 364.5 0.5 2.7 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 OAJ07592.1 - 1.9e-74 250.8 0.0 4.6e-74 249.5 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 OAJ07592.1 - 1.7e-41 141.7 0.0 3.7e-41 140.6 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 OAJ07592.1 - 4.4e-35 120.7 0.1 8.9e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 OAJ07592.1 - 2.1e-20 73.0 0.0 3.8e-19 69.0 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Nucleoplasmin PF03066.10 OAJ07592.1 - 0.19 11.2 12.0 0.64 9.5 8.3 1.9 1 0 0 1 1 1 0 Nucleoplasmin Apis_Csd PF11671.3 OAJ07592.1 - 0.31 10.8 5.1 0.96 9.2 3.5 1.9 1 0 0 1 1 1 0 Complementary sex determiner protein Usp PF00582.21 OAJ07593.1 - 4.4e-13 49.6 1.6 8.3e-13 48.7 0.2 2.1 2 1 0 2 2 2 1 Universal stress protein family AATF-Che1 PF13339.1 OAJ07593.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor WD40 PF00400.27 OAJ07595.1 - 5e-18 64.2 10.6 9.4e-07 28.4 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat DPPIV_N PF00930.16 OAJ07595.1 - 0.0031 16.1 0.5 0.096 11.2 0.3 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Rax2 PF12768.2 OAJ07595.1 - 0.0044 16.2 0.0 0.012 14.8 0.0 1.7 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 OAJ07595.1 - 0.1 12.1 0.0 49 3.5 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ARID PF01388.16 OAJ07596.1 - 2.5e-14 52.8 0.0 2.5e-14 52.8 0.0 3.8 6 0 0 6 6 6 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 OAJ07597.1 - 5.3e-68 228.9 0.0 7.8e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07597.1 - 6.3e-30 104.1 0.2 1.1e-28 100.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ07597.1 - 1.1e-06 27.9 2.3 0.00022 20.2 0.1 3.0 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 OAJ07597.1 - 0.017 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.1 OAJ07598.1 - 1.1e-10 41.9 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 OAJ07598.1 - 3.2e-05 23.7 0.0 0.00013 21.7 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain GMC_oxred_N PF00732.14 OAJ07599.1 - 3.2e-49 167.6 0.1 5.9e-49 166.8 0.1 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ07599.1 - 2.6e-33 115.3 0.0 4.7e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ07599.1 - 9.9e-07 28.6 0.0 2.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ07599.1 - 3.9e-06 25.9 0.0 0.00039 19.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 OAJ07599.1 - 0.00014 20.8 0.0 0.0003 19.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 OAJ07599.1 - 0.0002 20.4 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 OAJ07599.1 - 0.0093 15.8 0.0 0.036 13.9 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 OAJ07599.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 OAJ07599.1 - 0.035 13.8 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 OAJ07599.1 - 0.048 13.6 0.1 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 OAJ07599.1 - 0.077 11.4 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 OAJ07600.1 - 1.3e-19 70.1 39.0 3.5e-13 48.9 15.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 OAJ07600.1 - 3.5e-12 46.1 13.7 4.4e-12 45.7 3.5 2.3 2 0 0 2 2 2 2 Nodulin-like zf-CCHH PF10283.4 OAJ07600.1 - 0.026 14.3 2.3 0.047 13.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger (CX5CX6HX5H) motif Lustrin_cystein PF14625.1 OAJ07600.1 - 0.52 10.4 2.5 0.9 9.6 1.7 1.3 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain ATP_bind_4 PF01902.12 OAJ07602.1 - 8.5e-40 136.4 0.0 7.6e-38 130.0 0.0 2.4 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 OAJ07602.1 - 3.5e-22 78.4 0.1 2.1e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 OAJ07602.1 - 0.0097 14.5 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Ribosomal_L13e PF01294.13 OAJ07602.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L13e Peroxidase_2 PF01328.12 OAJ07603.1 - 2 7.0 3.8 1.1 7.8 0.4 1.9 1 1 0 2 2 2 0 Peroxidase, family 2 Glycoprotein_G PF00802.14 OAJ07603.1 - 2.6 7.1 18.4 4.1 6.4 12.8 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G MerR_2 PF13591.1 OAJ07603.1 - 8.4 6.0 10.7 6.2 6.4 0.5 3.6 2 1 1 3 3 3 0 MerR HTH family regulatory protein PRKCSH-like PF12999.2 OAJ07604.1 - 1e-42 145.6 4.8 1e-42 145.6 3.4 2.3 2 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 OAJ07604.1 - 2.5e-28 98.5 0.1 5.4e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 OAJ07604.1 - 3.6e-09 37.3 2.7 7.3e-09 36.3 1.9 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF3584 PF12128.3 OAJ07604.1 - 0.00091 16.7 1.1 0.00091 16.7 0.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Nup88 PF10168.4 OAJ07604.1 - 0.0016 16.3 0.5 0.022 12.6 0.3 2.0 2 0 0 2 2 2 1 Nuclear pore component DUF2968 PF11180.3 OAJ07604.1 - 0.011 15.0 4.3 0.017 14.5 2.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) bZIP_1 PF00170.16 OAJ07604.1 - 0.025 14.5 7.5 1 9.3 0.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor CDC37_N PF03234.9 OAJ07604.1 - 0.11 12.8 3.8 0.16 12.2 1.0 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding IncA PF04156.9 OAJ07604.1 - 2.6 7.6 10.2 0.29 10.6 0.8 2.5 3 0 0 3 3 3 0 IncA protein Syntaxin-6_N PF09177.6 OAJ07604.1 - 3.5 8.0 6.1 21 5.6 0.3 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DEAD PF00270.24 OAJ07606.1 - 3.4e-41 140.5 0.0 5.8e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07606.1 - 6.8e-24 83.5 0.0 1.8e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ07606.1 - 0.021 14.6 0.0 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 OAJ07607.1 - 4.8e-47 160.3 0.0 7.5e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07607.1 - 7.3e-20 71.1 0.0 5.6e-19 68.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ07607.1 - 1.9e-05 23.7 0.0 3.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ07607.1 - 2e-05 24.4 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ07607.1 - 0.0061 15.6 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LSM PF01423.17 OAJ07608.1 - 7.2e-17 60.6 0.2 1e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Bac_luciferase PF00296.15 OAJ07609.1 - 1.5e-62 211.5 1.0 1.9e-62 211.1 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MHC_I_C PF06623.6 OAJ07611.1 - 0.011 15.2 0.6 0.12 11.8 0.2 2.6 2 0 0 2 2 2 0 MHC_I C-terminus Ank_2 PF12796.2 OAJ07613.1 - 1.9e-20 73.0 0.5 3.6e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 OAJ07613.1 - 9.4e-15 53.5 12.7 3e-07 29.9 0.2 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 OAJ07613.1 - 9.7e-13 48.2 3.0 5.5e-06 26.7 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 OAJ07613.1 - 1.9e-12 46.9 2.5 9.6e-07 28.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 OAJ07613.1 - 1.1e-09 37.5 1.5 0.0096 16.0 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeat Kinesin PF00225.18 OAJ07614.1 - 3.7e-11 42.3 0.0 4.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Hydrolase_4 PF12146.3 OAJ07614.1 - 0.047 13.5 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Putative lysophospholipase F-box-like PF12937.2 OAJ07615.1 - 2.3e-11 43.2 0.0 4.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ07615.1 - 5.4e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain PS-DH PF14765.1 OAJ07615.1 - 0.07 12.2 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase DUF3760 PF12586.3 OAJ07615.1 - 0.08 12.7 0.2 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) cNMP_binding PF00027.24 OAJ07616.1 - 2.3e-40 136.2 0.0 1.8e-19 69.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 OAJ07616.1 - 1.6e-13 49.8 0.2 3e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit S4 PF01479.20 OAJ07617.1 - 1e-13 50.4 0.1 1.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 OAJ07617.1 - 0.0055 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.21 OAJ07618.1 - 4.8e-38 129.7 0.0 6.3e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 OAJ07618.1 - 0.053 13.2 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 OAJ07618.1 - 0.059 13.2 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain Glyco_hydro_30 PF02055.11 OAJ07619.1 - 6.1e-23 80.7 0.0 2.2e-22 78.9 0.0 1.8 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Abhydrolase_3 PF07859.8 OAJ07620.1 - 3.6e-23 82.2 0.2 6.7e-23 81.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07620.1 - 0.0034 17.1 0.1 0.0056 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 OAJ07620.1 - 0.029 13.6 0.1 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.3 OAJ07620.1 - 0.1 11.9 0.1 0.2 10.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1748 PF08520.5 OAJ07621.1 - 1.2e-26 92.0 0.0 1.4e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PIF1 PF05970.9 OAJ07622.1 - 3.6e-101 338.7 0.0 4.7e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 OAJ07622.1 - 1e-62 211.1 0.1 2.2e-62 210.0 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 OAJ07622.1 - 1.6e-07 29.5 0.1 2.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 OAJ07622.1 - 9.3e-06 25.3 0.0 3.1e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 OAJ07622.1 - 0.00033 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.7 OAJ07622.1 - 0.25 10.4 0.0 0.48 9.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Spc97_Spc98 PF04130.8 OAJ07626.1 - 7.6e-112 374.3 0.0 1.1e-111 373.9 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family CTDII PF01556.13 OAJ07627.1 - 2.1e-21 75.6 0.1 2.8e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 OAJ07627.1 - 1e-20 73.2 5.3 1.7e-20 72.5 3.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 OAJ07627.1 - 3.2e-16 59.1 16.7 5.5e-16 58.3 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.2 OAJ07627.1 - 3.3 7.5 10.8 32 4.4 8.2 2.0 1 1 1 2 2 2 0 Double zinc ribbon Ras PF00071.17 OAJ07628.1 - 4.3e-47 159.5 0.0 5.3e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ07628.1 - 2.1e-17 63.6 0.1 3.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ07628.1 - 1.5e-06 27.5 0.0 1.9e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 OAJ07628.1 - 7.9e-05 22.1 0.0 0.00013 21.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 OAJ07628.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 OAJ07628.1 - 0.031 14.2 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 OAJ07628.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 OAJ07628.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 AIG1 family DUF3628 PF12300.3 OAJ07632.1 - 8.5 6.3 14.3 0.2 11.6 1.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3628) ABC2_membrane PF01061.19 OAJ07633.1 - 1.1e-33 116.1 18.8 1.8e-33 115.4 13.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 OAJ07633.1 - 3.4e-14 53.3 0.8 6.4e-07 29.7 0.2 2.4 1 1 1 2 2 2 2 ABC transporter AAA_21 PF13304.1 OAJ07633.1 - 2.5e-07 30.9 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 OAJ07633.1 - 9.2e-06 25.1 0.1 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 OAJ07633.1 - 0.0006 20.0 0.1 0.0015 18.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 OAJ07633.1 - 0.0012 18.3 0.1 0.0031 17.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 OAJ07633.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 OAJ07633.1 - 0.0016 19.2 0.0 0.0029 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 OAJ07633.1 - 0.0026 17.9 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 OAJ07633.1 - 0.0027 17.7 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 OAJ07633.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 OAJ07633.1 - 0.016 15.2 0.1 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ07633.1 - 0.023 14.4 0.2 0.023 14.4 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 OAJ07633.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 OAJ07633.1 - 0.04 13.3 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 OAJ07633.1 - 0.041 14.2 0.2 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 OAJ07633.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B hEGF PF12661.2 OAJ07633.1 - 0.07 13.2 7.7 1.7 8.8 0.1 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF SbcCD_C PF13558.1 OAJ07633.1 - 0.071 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 OAJ07633.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 OAJ07633.1 - 0.15 11.9 0.1 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAJ07633.1 - 0.2 11.2 0.2 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.6 OAJ07633.1 - 0.27 9.8 0.0 0.42 9.2 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FeoB_C PF07664.7 OAJ07633.1 - 0.39 10.1 2.3 0.41 10.1 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus DUF3628 PF12300.3 OAJ07634.1 - 9.4 6.2 15.0 0.27 11.2 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3628) D-aminoacyl_C PF07908.7 OAJ07641.1 - 0.036 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 D-aminoacylase, C-terminal region Pyr_redox_dim PF02852.17 OAJ07641.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain CBM_20 PF00686.14 OAJ07641.1 - 0.11 12.0 0.4 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Starch binding domain Glyco_transf_20 PF00982.16 OAJ07643.1 - 2.6e-144 481.2 0.0 4.1e-144 480.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 OAJ07643.1 - 4.7e-22 78.0 0.0 8.2e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase ATG11 PF10377.4 OAJ07644.1 - 3.5e-27 94.8 0.0 7.8e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein 11 LPP PF04728.8 OAJ07644.1 - 0.026 14.2 11.6 3.3 7.5 0.0 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper AlphaC_N PF08829.5 OAJ07644.1 - 0.23 10.8 0.2 0.47 9.7 0.1 1.4 1 0 0 1 1 1 0 Alpha C protein N terminal Filament PF00038.16 OAJ07644.1 - 0.43 10.0 53.3 0.14 11.6 26.4 3.3 2 1 1 3 3 3 0 Intermediate filament protein Sec23_trunk PF04811.10 OAJ07645.1 - 8.2e-72 241.4 0.0 1.3e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 OAJ07645.1 - 7.8e-24 83.0 0.5 1.5e-23 82.1 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 OAJ07645.1 - 9.2e-17 60.3 7.9 1.7e-16 59.5 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 OAJ07645.1 - 1.6e-15 57.4 0.0 4.4e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 OAJ07645.1 - 8.2e-10 38.2 0.0 1.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 OAJ07645.1 - 0.0036 17.1 1.1 0.0036 17.1 0.8 2.0 2 0 0 2 2 2 1 WW domain BAR PF03114.13 OAJ07646.1 - 4.5e-11 42.7 1.4 4.5e-11 42.7 1.0 1.4 2 0 0 2 2 2 1 BAR domain BAR_2 PF10455.4 OAJ07646.1 - 0.0018 17.2 0.2 0.0031 16.5 0.1 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PapD-like PF14874.1 OAJ07647.1 - 2.7e-05 24.0 0.1 0.032 14.1 0.2 4.2 4 0 0 4 4 4 1 Flagellar-associated PapD-like FixG_C PF11614.3 OAJ07647.1 - 0.00014 21.9 0.7 0.42 10.7 0.1 4.2 4 0 0 4 4 4 2 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF1090 PF06476.7 OAJ07647.1 - 0.049 13.3 2.3 0.13 11.8 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) LRR_4 PF12799.2 OAJ07648.1 - 6e-21 73.6 11.5 2.9e-08 33.1 3.2 5.9 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ07648.1 - 8e-16 57.5 14.1 6.5e-08 32.2 4.8 4.5 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 OAJ07648.1 - 4.2e-10 38.2 9.1 1 9.6 0.2 8.1 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.1 OAJ07648.1 - 3.6e-08 32.6 14.2 1.3 9.3 0.2 7.7 7 0 0 7 7 7 4 Leucine Rich repeat LRR_7 PF13504.1 OAJ07648.1 - 2.7e-07 29.6 15.4 1.5 9.3 0.0 8.0 8 0 0 8 8 8 2 Leucine rich repeat zf-CCCH PF00642.19 OAJ07648.1 - 7.7e-06 25.4 7.7 0.0046 16.6 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 OAJ07649.1 - 1.2e-18 66.3 15.5 4.7e-11 42.0 1.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RhoGEF PF00621.15 OAJ07650.1 - 8.2e-27 94.2 0.2 2e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain TMF_DNA_bd PF12329.3 OAJ07650.1 - 5.8 6.8 7.8 0.38 10.5 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3040 PF11239.3 OAJ07651.1 - 0.044 13.8 3.0 1.6 8.8 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF2892 PF11127.3 OAJ07651.1 - 1.5 8.7 7.9 24 4.8 2.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) DUF3446 PF11928.3 OAJ07652.1 - 0.019 15.1 0.2 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) adh_short PF00106.20 OAJ07653.1 - 4.8e-17 62.3 0.1 8.1e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 OAJ07653.1 - 5.4e-06 26.1 0.3 1.2e-05 25.0 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 OAJ07653.1 - 1.6e-05 24.7 0.1 2.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L7Ae PF01248.21 OAJ07654.1 - 1.3e-21 75.9 0.1 2.5e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 OAJ07654.1 - 0.0043 16.9 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 CRT10 PF08728.5 OAJ07654.1 - 0.6 8.0 5.1 0.68 7.8 3.5 1.0 1 0 0 1 1 1 0 CRT10 CDK2AP PF09806.4 OAJ07654.1 - 1.4 9.0 8.2 2.4 8.3 5.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SAPS PF04499.10 OAJ07654.1 - 2.2 6.8 5.2 2.4 6.6 3.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.1 OAJ07654.1 - 8.1 6.1 15.3 1.2 8.8 0.6 2.4 1 1 2 3 3 3 0 FAM176 family Fe-S_biosyn PF01521.15 OAJ07655.1 - 2.2e-14 53.3 0.0 3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 OAJ07655.1 - 7.2 5.8 15.7 9.5 5.4 10.9 1.2 1 0 0 1 1 1 0 Vta1 like MutS_V PF00488.16 OAJ07656.1 - 3.7e-79 265.4 0.2 7e-79 264.5 0.0 1.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 OAJ07656.1 - 3.9e-42 144.3 0.7 1.1e-41 142.8 0.5 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 OAJ07656.1 - 1.7e-34 118.1 0.0 4.7e-34 116.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain I zf-C2H2_3 PF13878.1 OAJ07656.1 - 7.8e-13 47.7 3.3 1.5e-12 46.8 2.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MutS_II PF05188.12 OAJ07656.1 - 7.4e-11 42.2 0.1 2e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 MutS domain II Acetyltransf_13 PF13880.1 OAJ07656.1 - 7.8e-10 38.3 0.0 3e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 ESCO1/2 acetyl-transferase MutS_IV PF05190.13 OAJ07656.1 - 2.7e-07 30.6 2.0 1.1e-06 28.7 0.8 2.2 2 0 0 2 2 2 1 MutS family domain IV Acetyltransf_1 PF00583.19 OAJ07656.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SKN1 PF03935.10 OAJ07657.1 - 1.9e-175 583.8 1.0 2.3e-175 583.5 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 OAJ07657.1 - 3.9e-06 26.2 0.2 0.023 14.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 HMG_box PF00505.14 OAJ07658.1 - 2.2e-20 72.6 12.4 7.1e-10 39.0 3.0 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ07658.1 - 1.7e-17 63.5 7.5 3.6e-09 36.8 0.5 2.7 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.1 OAJ07658.1 - 0.0095 15.6 0.4 0.03 14.0 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF3429 PF11911.3 OAJ07659.1 - 7.3e-39 132.9 13.9 1e-38 132.5 9.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) RabGAP-TBC PF00566.13 OAJ07660.1 - 3.2e-48 164.0 0.0 4.2e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Uso1_p115_head PF04869.9 OAJ07661.1 - 2.8e-33 115.0 0.0 1.2e-31 109.6 0.0 3.3 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 OAJ07661.1 - 3e-06 27.2 21.0 3e-06 27.2 14.6 2.7 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region WEMBL PF05701.6 OAJ07661.1 - 0.0001 20.9 31.5 0.0001 20.9 21.8 2.1 2 0 0 2 2 2 1 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 OAJ07661.1 - 0.00052 19.7 12.2 0.00052 19.7 8.5 2.8 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein ERM PF00769.14 OAJ07661.1 - 0.19 11.2 35.2 1.4 8.4 24.4 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.1 OAJ07661.1 - 0.44 9.6 26.5 1.4 8.1 3.1 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EMG1 PF03587.9 OAJ07662.1 - 2.4e-74 248.9 0.0 3e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Med10 PF09748.4 OAJ07663.1 - 2.6e-14 53.1 0.0 3.2e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Acetyltransf_5 PF13444.1 OAJ07665.1 - 0.00021 21.8 0.0 0.0023 18.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 OAJ07665.1 - 0.00028 20.8 0.1 0.0013 18.7 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family PP2C PF00481.16 OAJ07666.1 - 3.3e-68 229.8 0.2 2.2e-52 178.0 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C MFS_1 PF07690.11 OAJ07667.1 - 2.2e-41 141.7 38.0 2.2e-41 141.7 26.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 OAJ07667.1 - 2.2e-05 22.9 3.1 3.4e-05 22.2 2.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMO-like PF00743.14 OAJ07669.1 - 8.1e-23 80.4 0.0 2.1e-22 79.0 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 OAJ07669.1 - 3.9e-22 79.3 0.1 2.2e-21 76.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 OAJ07669.1 - 7.6e-11 42.2 0.7 0.00017 21.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 OAJ07669.1 - 7.3e-10 38.7 1.1 6.3e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 OAJ07669.1 - 2.3e-09 36.6 1.3 1.1e-06 27.7 0.0 2.9 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 OAJ07669.1 - 3.2e-07 29.5 0.6 1.8e-05 23.8 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 OAJ07669.1 - 4.8e-06 26.8 4.2 0.015 15.6 0.6 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 OAJ07669.1 - 9e-06 24.4 0.1 0.0095 14.4 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 OAJ07669.1 - 2.6e-05 24.0 5.1 0.012 15.4 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 OAJ07669.1 - 4.3e-05 22.7 3.4 0.0039 16.3 0.2 2.5 3 0 0 3 3 3 2 Thi4 family AlaDh_PNT_C PF01262.16 OAJ07669.1 - 0.0015 18.1 2.6 0.13 11.7 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 OAJ07669.1 - 0.0021 18.2 0.0 0.24 11.6 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 OAJ07669.1 - 0.0025 16.9 0.0 0.0072 15.4 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 OAJ07669.1 - 0.0042 16.7 0.3 0.0042 16.7 0.2 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 OAJ07669.1 - 0.0047 17.0 0.2 0.46 10.5 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 OAJ07669.1 - 0.0052 15.9 0.0 0.054 12.5 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 OAJ07669.1 - 0.0081 15.0 0.6 0.0081 15.0 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 OAJ07669.1 - 0.014 14.3 3.4 1.1 7.9 0.4 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 OAJ07669.1 - 0.37 9.7 1.7 2.1 7.3 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 OAJ07669.1 - 1.5 8.1 5.4 0.21 10.9 0.6 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2910 PF11139.3 OAJ07674.1 - 0.055 12.5 0.1 0.13 11.3 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) UCR_Fe-S_N PF10399.4 OAJ07674.1 - 0.93 8.7 0.0 0.93 8.7 0.0 2.4 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CK1gamma_C PF12605.3 OAJ07676.1 - 0.29 11.7 4.4 0.4 11.2 3.1 1.2 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal MFS_1 PF07690.11 OAJ07678.1 - 4.5e-37 127.5 36.3 2.2e-36 125.3 25.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ07678.1 - 8.5e-10 37.4 19.7 2.5e-09 35.9 13.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 OAJ07678.1 - 3.8e-07 29.0 20.1 3.8e-07 29.0 14.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Acyltransferase PF01553.16 OAJ07679.1 - 1.1e-10 41.0 0.0 0.00021 20.7 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase tRNA_Me_trans PF03054.11 OAJ07680.1 - 8.8e-92 307.3 0.0 1.6e-79 267.0 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.12 OAJ07680.1 - 1.1e-05 24.4 0.0 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.9 OAJ07680.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 OAJ07680.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Sugar_tr PF00083.19 OAJ07681.1 - 3.4e-40 137.9 26.4 2.3e-24 85.8 5.0 2.2 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 OAJ07681.1 - 1.1e-16 60.5 33.9 7.8e-09 34.7 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 OAJ07682.1 - 3.4e-07 29.8 0.6 0.012 15.4 0.1 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 OAJ07682.1 - 0.0058 15.4 0.5 0.013 14.2 0.3 1.5 1 0 0 1 1 1 1 Nup133 N terminal like CRT10 PF08728.5 OAJ07682.1 - 0.49 8.3 0.0 0.72 7.7 0.0 1.1 1 0 0 1 1 1 0 CRT10 E1-E2_ATPase PF00122.15 OAJ07683.1 - 7e-14 51.4 0.0 2.2e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 OAJ07683.1 - 2.4e-13 50.7 0.1 6.9e-13 49.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 OAJ07683.1 - 1.4e-12 47.4 0.0 4.6e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 OAJ07683.1 - 1.8e-12 48.1 0.1 6e-06 26.8 0.0 4.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 OAJ07683.1 - 0.0005 19.7 0.7 0.0065 16.0 0.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_M16 PF00675.15 OAJ07684.1 - 1.3e-17 63.9 0.4 5e-17 62.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 OAJ07684.1 - 1.1e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain MFS_1 PF07690.11 OAJ07685.1 - 3.2e-42 144.5 34.9 7.9e-42 143.2 24.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 OAJ07685.1 - 5.2e-16 57.9 15.2 7.3e-16 57.4 10.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM154 PF15102.1 OAJ07685.1 - 0.77 9.4 5.5 0.2 11.3 0.2 2.3 2 1 0 2 2 2 0 TMEM154 protein family Ndc1_Nup PF09531.5 OAJ07687.1 - 4.1e-08 32.1 19.7 6.4e-07 28.1 0.7 4.7 4 1 0 4 4 4 4 Nucleoporin protein Ndc1-Nup Na_Ca_ex PF01699.19 OAJ07689.1 - 2e-24 85.7 32.5 3e-13 49.5 8.0 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 OAJ07689.1 - 9.1e-14 51.6 5.0 9.1e-14 51.6 3.5 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Rtf2 PF04641.7 OAJ07689.1 - 0.6 9.2 6.2 1.4 8.1 4.3 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 OAJ07689.1 - 1.4 8.7 9.4 6.8 6.4 6.5 2.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DEAD PF00270.24 OAJ07690.1 - 3e-46 157.0 0.0 3.3e-45 153.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07690.1 - 4.9e-26 90.3 0.0 1.6e-25 88.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ctf8 PF09696.5 OAJ07691.1 - 3.2e-18 65.6 0.1 2.1e-11 43.6 0.0 2.7 2 1 0 2 2 2 2 Ctf8 Nop14 PF04147.7 OAJ07691.1 - 1.1 7.0 13.3 1.4 6.7 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family SRP-alpha_N PF04086.8 OAJ07691.1 - 5.4 6.3 10.6 8 5.7 7.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ATP-synt_S1 PF05827.7 OAJ07694.1 - 0.053 12.8 0.1 0.084 12.1 0.0 1.3 1 1 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF2892 PF11127.3 OAJ07694.1 - 0.42 10.4 0.1 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Nucleoplasmin PF03066.10 OAJ07697.1 - 0.066 12.7 1.7 0.12 11.8 1.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin LAT PF15234.1 OAJ07697.1 - 0.19 11.1 6.4 0.38 10.1 4.4 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells CENP-B_dimeris PF09026.5 OAJ07697.1 - 0.63 10.3 5.7 1.3 9.3 3.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 OAJ07697.1 - 0.65 9.2 1.0 0.97 8.6 0.7 1.2 1 0 0 1 1 1 0 NOA36 protein Phage_Gp23 PF10669.4 OAJ07697.1 - 2.5 8.2 9.4 0.59 10.2 2.8 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) VHS PF00790.14 OAJ07698.1 - 7.4e-21 74.2 0.0 1.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 OAJ07698.1 - 0.00021 21.2 1.5 0.00061 19.7 1.1 1.8 1 0 0 1 1 1 1 GAT domain Tfb4 PF03850.9 OAJ07698.1 - 4.5 6.4 5.5 7.7 5.6 3.8 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 RR_TM4-6 PF06459.7 OAJ07698.1 - 9.1 6.0 14.2 1.4 8.7 6.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MFS_1_like PF12832.2 OAJ07699.1 - 2.6e-18 65.5 0.2 2.6e-18 65.5 0.2 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF373 PF04123.8 OAJ07699.1 - 5.9 5.8 5.3 11 4.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TPR_11 PF13414.1 OAJ07700.1 - 2.6e-24 84.6 12.1 2.6e-17 62.2 3.0 2.6 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 OAJ07700.1 - 5.3e-24 82.7 2.1 5.4e-09 35.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 OAJ07700.1 - 5.3e-16 57.1 12.2 3.6e-07 29.5 0.0 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 OAJ07700.1 - 1.6e-12 46.5 1.7 1.4e-06 27.9 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 OAJ07700.1 - 3.2e-11 42.8 7.6 3e-05 24.2 0.0 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 OAJ07700.1 - 2e-09 37.8 8.3 1.7e-05 25.3 1.8 3.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 OAJ07700.1 - 3.9e-09 35.6 1.5 0.01 15.5 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 OAJ07700.1 - 6.5e-09 34.9 0.7 5.9e-05 22.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 OAJ07700.1 - 3.5e-07 30.0 0.7 3.5e-07 30.0 0.5 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 OAJ07700.1 - 5.9e-07 29.7 1.8 0.0016 18.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 OAJ07700.1 - 0.00045 20.2 0.3 0.00075 19.5 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 OAJ07700.1 - 0.00088 19.0 4.7 0.0045 16.8 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 OAJ07700.1 - 0.0011 18.8 0.9 0.025 14.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat T4SS PF07996.6 OAJ07700.1 - 0.0012 18.6 0.2 0.0012 18.6 0.1 2.3 2 1 0 2 2 2 1 Type IV secretion system proteins NARP1 PF12569.3 OAJ07700.1 - 0.012 14.3 0.4 0.18 10.5 0.2 2.1 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 RPN7 PF10602.4 OAJ07700.1 - 0.12 11.7 0.4 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 BTAD PF03704.12 OAJ07700.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 OAJ07700.1 - 0.99 9.5 5.0 1.2 9.3 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 OAJ07700.1 - 2.9 8.5 10.5 3.8 8.1 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Ras PF00071.17 OAJ07701.1 - 3.9e-57 192.1 0.0 4.8e-57 191.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 OAJ07701.1 - 2.4e-19 69.9 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 OAJ07701.1 - 3.1e-16 59.0 0.0 2.9e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 OAJ07701.1 - 7.4e-08 31.8 0.0 8.3e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 OAJ07701.1 - 3.1e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 OAJ07701.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TCP PF03634.8 OAJ07701.1 - 0.044 14.1 0.7 0.07 13.4 0.5 1.3 1 0 0 1 1 1 0 TCP family transcription factor Ashwin PF15323.1 OAJ07701.1 - 0.07 13.1 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Developmental protein Sporozoite_P67 PF05642.6 OAJ07701.1 - 0.51 8.1 7.6 0.26 9.1 1.7 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen COG5 PF10392.4 OAJ07702.1 - 6e-12 45.6 0.7 6e-12 45.6 0.5 1.7 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Transthyretin PF00576.16 OAJ07703.1 - 5.5e-33 113.1 0.0 3.5e-32 110.6 0.0 1.8 1 1 0 1 1 1 1 HIUase/Transthyretin family Sec63 PF02889.11 OAJ07704.1 - 1.9e-45 155.4 0.0 2.8e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 OAJ07704.1 - 1.1e-27 96.5 0.0 2.2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07704.1 - 9.2e-10 38.2 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ07704.1 - 2.8e-08 33.7 0.0 6.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 OAJ07704.1 - 0.0053 16.4 0.0 0.022 14.5 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain HHH_5 PF14520.1 OAJ07704.1 - 0.0055 16.8 0.5 0.029 14.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain UvrD-helicase PF00580.16 OAJ07704.1 - 0.014 14.7 0.2 0.056 12.7 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 OAJ07704.1 - 0.018 14.5 0.5 0.9 8.9 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain T2SE PF00437.15 OAJ07704.1 - 0.021 13.7 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 OAJ07704.1 - 0.094 12.8 0.1 0.45 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF177 PF02620.12 OAJ07705.1 - 0.58 10.2 0.0 0.58 10.2 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized ACR, COG1399 GST_C_2 PF13410.1 OAJ07706.1 - 1.8e-16 59.7 0.0 3.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 OAJ07706.1 - 8.3e-14 51.3 0.0 1.9e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 OAJ07706.1 - 2.7e-07 30.4 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 OAJ07706.1 - 3.4e-06 27.4 0.0 6e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 OAJ07706.1 - 0.018 15.2 0.0 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Pmp3 PF01679.12 OAJ07707.1 - 3.7e-13 48.9 3.3 5.1e-13 48.4 2.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator AA_permease PF00324.16 OAJ07708.1 - 5.2e-118 394.4 36.4 5.9e-118 394.2 25.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 OAJ07708.1 - 3.6e-35 121.3 42.3 4.2e-35 121.1 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease Cyt-b5 PF00173.23 OAJ07710.1 - 3.8e-09 36.2 0.0 5.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 OAJ07711.1 - 2.9e-24 85.3 0.0 4.7e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 OAJ07711.1 - 2.5e-09 36.8 2.8 4.9e-09 35.9 2.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 OAJ07712.1 - 5.4e-23 81.0 0.0 8.6e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 OAJ07712.1 - 5e-09 35.8 0.0 9.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Redoxin PH PF00169.24 OAJ07713.1 - 6.9e-08 32.6 0.0 3.4e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 OAJ07713.1 - 3e-07 30.6 0.3 0.0031 17.6 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 OAJ07713.1 - 0.00081 19.6 0.1 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain hNIFK_binding PF12196.3 OAJ07714.1 - 0.12 11.7 5.2 0.29 10.5 0.0 3.0 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK MTP18 PF10558.4 OAJ07715.1 - 5.7e-51 172.3 1.0 1.4e-50 171.0 0.5 1.8 2 1 0 2 2 2 1 Mitochondrial 18 KDa protein (MTP18) DUF2562 PF10814.3 OAJ07715.1 - 3 7.7 9.0 4.7 7.1 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) TPR_14 PF13428.1 OAJ07716.1 - 1.5 9.6 10.2 3.1 8.6 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TauD PF02668.11 OAJ07725.1 - 2.2e-34 119.2 0.0 4.5e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 OAJ07725.1 - 9.8e-05 22.6 4.1 0.00012 22.3 0.0 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF971) zf-H2C2_2 PF13465.1 OAJ07726.1 - 4.8e-13 48.7 7.8 2.7e-05 24.2 0.0 4.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ07726.1 - 2.6e-11 43.1 15.8 0.00024 21.2 0.5 4.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ07726.1 - 2.7e-05 24.2 32.7 0.0002 21.4 0.0 4.6 4 1 0 4 4 4 3 C2H2-type zinc finger Suf PF05843.9 OAJ07726.1 - 0.095 12.4 10.7 0.75 9.4 1.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-BED PF02892.10 OAJ07726.1 - 0.12 12.1 0.1 0.12 12.1 0.0 2.5 2 1 1 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 OAJ07726.1 - 0.75 9.5 9.1 0.049 13.3 0.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type EPL1 PF10513.4 OAJ07726.1 - 6.1 7.0 16.4 8.5 6.5 4.0 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like FAD_binding_7 PF03441.9 OAJ07727.1 - 1.9e-78 263.4 0.0 2.7e-78 262.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 OAJ07727.1 - 2.1e-36 125.1 0.0 3.8e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Peptidase_C37 PF05416.7 OAJ07727.1 - 5.7 5.1 7.4 9.6 4.3 5.1 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase NPV_P10 PF05531.7 OAJ07729.1 - 0.27 11.5 7.7 1.2 9.4 0.0 4.0 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4239 PF14023.1 OAJ07729.1 - 0.56 9.5 7.4 3.5 6.9 3.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4239) Fasciclin PF02469.17 OAJ07730.1 - 7.4e-14 51.8 0.0 3.2e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain DUF1206 PF06724.6 OAJ07730.1 - 4.5 7.1 7.5 1.7 8.4 1.7 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) RVT_1 PF00078.22 OAJ07731.1 - 3.8e-16 59.0 0.0 7.3e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 OAJ07731.1 - 1.2e-15 57.6 0.0 4.5e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 OAJ07731.1 - 0.0019 17.6 0.2 0.0078 15.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.18 OAJ07731.1 - 3.7 7.6 10.6 0.045 13.6 2.0 1.9 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_cc PF11790.3 OAJ07732.1 - 1.5e-49 168.6 0.8 1.9e-49 168.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TFIIA PF03153.8 OAJ07732.1 - 0.18 11.7 6.5 0.26 11.1 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2207 PF09972.4 OAJ07734.1 - 0.051 12.1 1.3 1 7.8 0.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.1 OAJ07734.1 - 0.077 12.9 2.9 4.6 7.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Lipocalin_2 PF08212.7 OAJ07735.1 - 2.3e-16 59.9 0.0 3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain BP28CT PF08146.7 OAJ07736.1 - 4e-34 117.5 5.4 8.9e-34 116.4 0.2 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 OAJ07736.1 - 1.6e-07 31.3 0.9 1.6e-07 31.3 0.6 5.6 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 Carb_kinase PF01256.12 OAJ07737.1 - 1.2e-53 181.9 0.0 1.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 OAJ07737.1 - 0.0017 17.5 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.1 OAJ07737.1 - 0.19 11.3 0.8 0.47 10.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4516) DUF92 PF01940.11 OAJ07738.1 - 5.5e-54 182.7 4.7 7.5e-52 175.7 3.3 2.2 1 1 0 1 1 1 1 Integral membrane protein DUF92 COG6 PF06419.6 OAJ07739.1 - 3.3e-105 352.5 0.0 9.8e-88 294.8 0.0 2.8 2 1 0 2 2 2 2 Conserved oligomeric complex COG6 DUF4201 PF13870.1 OAJ07739.1 - 0.03 13.7 0.1 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3450 PF11932.3 OAJ07739.1 - 0.078 12.2 1.5 0.14 11.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADK PF00406.17 OAJ07740.1 - 3.4e-56 189.3 0.1 4.1e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 OAJ07740.1 - 1.9e-13 49.8 0.0 4.7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Zeta_toxin PF06414.7 OAJ07740.1 - 7.7e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 OAJ07740.1 - 0.00028 20.7 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 OAJ07740.1 - 0.026 15.3 0.0 0.036 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 OAJ07740.1 - 0.03 14.0 0.1 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 OAJ07740.1 - 0.054 13.7 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 OAJ07740.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3493 PF11998.3 OAJ07741.1 - 0.042 13.7 0.1 0.042 13.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) ATP-synt_ab PF00006.20 OAJ07742.1 - 1.1e-69 234.2 0.0 1.7e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 OAJ07742.1 - 1.9e-23 83.0 0.0 5.7e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 OAJ07742.1 - 9.5e-18 64.1 2.3 2.5e-17 62.8 1.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 OAJ07742.1 - 0.00039 20.2 1.6 0.00085 19.1 1.1 1.6 1 0 0 1 1 1 1 HAS barrel domain ICE2 PF08426.5 OAJ07743.1 - 1e-40 139.6 0.0 3.8e-20 71.8 0.0 3.6 3 1 0 3 3 3 3 ICE2 UQ_con PF00179.21 OAJ07744.1 - 6.4e-47 158.5 0.0 7.2e-47 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ07744.1 - 4.8e-06 26.3 0.0 5.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 OAJ07744.1 - 0.012 15.4 1.8 0.029 14.2 1.3 1.9 1 1 0 1 1 1 0 RWD domain DnaJ PF00226.26 OAJ07745.1 - 9.3e-23 79.7 0.3 1.4e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Acid_PPase PF12689.2 OAJ07746.1 - 9.1e-57 191.3 0.0 1.1e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 OAJ07746.1 - 0.00021 21.5 0.4 0.00093 19.4 0.2 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 OAJ07746.1 - 0.00024 20.7 0.0 0.00031 20.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_4 PF07721.9 OAJ07746.1 - 0.31 11.6 4.1 1.8 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat UPRTase PF14681.1 OAJ07747.1 - 1.5e-63 213.7 0.0 1.7e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 OAJ07747.1 - 4.9e-08 32.7 0.0 8.1e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Abhydrolase_5 PF12695.2 OAJ07748.1 - 0.0006 19.5 0.0 0.0014 18.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 OAJ07748.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) SRP-alpha_N PF04086.8 OAJ07749.1 - 0.57 9.5 5.2 0.52 9.6 0.3 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DPBB_1 PF03330.13 OAJ07751.1 - 1.3e-10 41.0 1.0 3.7e-10 39.6 0.7 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 OAJ07751.1 - 0.00093 18.8 0.2 0.0017 18.0 0.2 1.4 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 OAJ07751.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Cerato-platanin SDA1 PF05285.7 OAJ07751.1 - 3.3 6.8 12.2 5.1 6.2 8.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 OAJ07751.1 - 3.5 5.4 15.7 4.3 5.1 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ07751.1 - 5.5 5.3 11.7 7 5.0 8.1 1.1 1 0 0 1 1 1 0 Daxx Family EF_assoc_1 PF08355.7 OAJ07752.1 - 0.0014 17.8 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 EF hand associated DUF605 PF04652.11 OAJ07752.1 - 0.19 11.0 7.6 0.24 10.7 5.2 1.1 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 OAJ07752.1 - 0.29 10.4 4.3 0.56 9.5 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator RGS PF00615.14 OAJ07753.1 - 3.3e-35 120.7 2.7 5.5e-25 87.7 0.3 3.7 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.16 OAJ07753.1 - 5.6e-14 51.6 0.0 4e-07 29.6 0.0 2.8 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Hist_deacetyl PF00850.14 OAJ07754.1 - 1.4e-93 313.6 0.1 2.3e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 OAJ07754.1 - 5.8e-13 48.6 0.0 5.5e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Arb2 domain adh_short PF00106.20 OAJ07755.1 - 1.9e-23 83.1 0.2 3.2e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 OAJ07755.1 - 1.4e-14 54.4 0.4 1.8e-14 54.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 OAJ07755.1 - 1.5e-05 24.7 1.1 4.5e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 OAJ07755.1 - 8.1e-05 22.1 0.1 0.00019 20.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 OAJ07755.1 - 0.00016 21.7 0.3 0.00026 21.0 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 OAJ07755.1 - 0.0025 17.5 0.2 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HAD_2 PF13419.1 OAJ07757.1 - 6.7e-10 39.4 0.0 1.6e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 OAJ07757.1 - 0.00029 21.3 0.1 0.00056 20.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 OAJ07757.1 - 0.0014 18.7 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 OAJ07757.1 - 0.023 14.4 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 HAD-hyrolase-like Dabb PF07876.7 OAJ07757.1 - 0.067 13.6 0.0 5.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain SH3_9 PF14604.1 OAJ07758.1 - 2e-08 33.6 0.0 3.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 OAJ07758.1 - 2e-06 27.1 0.0 3.9e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Lipocalin_2 PF08212.7 OAJ07759.1 - 4.2e-10 39.5 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Leo1 PF04004.8 OAJ07760.1 - 1.4e-43 148.5 0.8 3.9e-43 147.1 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein API5 PF05918.6 OAJ07760.1 - 0.58 8.5 4.1 0.89 7.9 2.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Abhydrolase_6 PF12697.2 OAJ07761.1 - 2.9e-29 102.5 0.0 4.7e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ07761.1 - 2e-22 79.8 0.0 2.3e-19 69.8 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07761.1 - 5.9e-11 42.3 0.2 2e-10 40.6 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 OAJ07761.1 - 7.9e-05 22.1 0.9 0.00025 20.5 0.6 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 OAJ07761.1 - 0.0021 17.3 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 OAJ07761.1 - 0.0025 17.1 0.0 1.4 8.1 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 OAJ07761.1 - 0.0026 17.2 0.1 0.42 10.0 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 OAJ07761.1 - 0.0036 16.5 0.1 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase PGAP1 PF07819.8 OAJ07761.1 - 0.066 12.7 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Nol1_Nop2_Fmu PF01189.12 OAJ07762.1 - 2e-30 106.1 0.0 4.8e-18 65.5 0.0 4.0 3 1 0 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 OAJ07762.1 - 0.051 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CBFD_NFYB_HMF PF00808.18 OAJ07763.1 - 1.4e-13 50.6 0.4 2.8e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 OAJ07763.1 - 9.4e-05 22.4 0.4 0.00016 21.7 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LRR19-TM PF15176.1 OAJ07763.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.2 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Ku PF02735.11 OAJ07764.1 - 1.2e-27 96.5 0.0 9.8e-23 80.6 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 OAJ07764.1 - 4.1e-16 59.0 0.1 7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 OAJ07764.1 - 3.7e-09 35.8 0.0 9e-09 34.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 OAJ07764.1 - 7e-06 26.4 0.3 0.19 12.2 0.0 2.8 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm TRAUB PF08164.7 OAJ07765.1 - 7.6e-23 80.4 0.1 1.2e-21 76.5 0.0 3.1 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 OAJ07765.1 - 3e-08 33.8 5.7 3e-08 33.8 4.0 3.5 3 1 1 4 4 4 1 Apoptosis antagonizing transcription factor Pkinase PF00069.20 OAJ07766.1 - 2.5e-71 239.8 0.0 3.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07766.1 - 2.3e-35 121.9 0.0 3.2e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MIP-T3 PF10243.4 OAJ07766.1 - 0.013 13.9 63.7 0.005 15.3 12.2 3.2 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 Kinase-like PF14531.1 OAJ07766.1 - 0.029 13.3 0.0 0.095 11.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RNA_pol_I_TF PF04090.7 OAJ07767.1 - 0.00037 19.8 0.0 0.0012 18.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor Sec62 PF03839.11 OAJ07768.1 - 4e-44 150.7 6.2 8.4e-44 149.6 4.3 1.6 1 1 0 1 1 1 1 Translocation protein Sec62 GMC_oxred_N PF00732.14 OAJ07769.1 - 2.3e-51 174.7 0.0 3e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 OAJ07769.1 - 6.1e-32 110.8 0.1 9.6e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 OAJ07769.1 - 6.5e-05 22.8 0.1 0.00016 21.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 OAJ07769.1 - 0.00017 20.5 0.0 0.0008 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 OAJ07769.1 - 0.0002 20.3 0.0 0.0018 17.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GDI PF00996.13 OAJ07769.1 - 0.00023 19.6 0.0 0.00034 19.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 OAJ07769.1 - 0.0018 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 OAJ07769.1 - 0.0034 16.3 0.0 0.03 13.2 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 OAJ07769.1 - 0.0062 15.4 0.0 0.018 13.9 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 OAJ07769.1 - 0.019 13.4 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 OAJ07769.1 - 0.048 12.7 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 OAJ07769.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 OAJ07769.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 OAJ07769.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 OAJ07769.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.19 OAJ07770.1 - 3.6e-12 46.1 0.0 4.3e-11 42.5 0.0 2.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 OAJ07770.1 - 3.5e-08 33.3 0.0 9.9e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 OAJ07770.1 - 5.6e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 OAJ07770.1 - 0.0017 18.1 0.2 0.043 13.5 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 OAJ07770.1 - 0.007 15.0 0.0 0.014 14.0 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 OAJ07770.1 - 0.08 13.3 0.0 5.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase E1-E2_ATPase PF00122.15 OAJ07771.1 - 1.3 8.0 4.3 0.3 10.0 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase STE2 PF02116.10 OAJ07771.1 - 1.6 7.7 10.0 8 5.3 6.9 1.9 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR p450 PF00067.17 OAJ07772.1 - 2e-38 132.1 0.0 4.9e-38 130.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 TF_AP-2 PF03299.9 OAJ07772.1 - 0.076 12.5 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Transcription factor AP-2 SUI1 PF01253.17 OAJ07773.1 - 1.6e-31 107.9 1.0 2e-31 107.6 0.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 UCR_14kD PF02271.11 OAJ07775.1 - 3.5e-37 126.3 0.4 4e-37 126.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit BUD22 PF09073.5 OAJ07779.1 - 1.9 7.4 40.2 0.12 11.3 23.3 2.1 2 0 0 2 2 2 0 BUD22 Secretin_N_2 PF07655.8 OAJ07779.1 - 3.7 7.9 13.1 10 6.6 9.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Mito_carr PF00153.22 OAJ07780.1 - 2.7e-62 206.4 4.4 1.2e-20 72.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HK PF02110.10 OAJ07781.1 - 1.3e-63 214.4 1.5 5.6e-60 202.5 1.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 OAJ07781.1 - 3.4e-43 146.8 0.2 1.6e-42 144.6 0.1 2.0 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 OAJ07781.1 - 2.3e-07 30.2 0.4 4.1e-07 29.4 0.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Actin PF00022.14 OAJ07782.1 - 1.2e-30 106.2 0.0 7.9e-20 70.6 0.0 3.5 3 1 0 3 3 3 3 Actin Septin PF00735.13 OAJ07783.1 - 9.6e-76 254.4 0.5 1.4e-75 253.9 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 OAJ07783.1 - 7.2e-09 35.6 0.0 4.3e-08 33.1 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 OAJ07783.1 - 2e-07 30.6 0.5 1.6e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 OAJ07783.1 - 3.4e-07 29.5 0.0 6.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 OAJ07783.1 - 0.00014 21.2 0.6 0.00031 20.1 0.4 1.6 1 1 0 1 1 1 1 Ras family AAA_10 PF12846.2 OAJ07783.1 - 0.00021 20.8 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 OAJ07783.1 - 0.00042 19.9 0.0 0.00073 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 OAJ07783.1 - 0.00053 20.4 0.8 0.0025 18.2 0.1 2.4 3 0 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 OAJ07783.1 - 0.0006 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Gtr1_RagA PF04670.7 OAJ07783.1 - 0.00066 18.8 0.1 0.0076 15.4 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 OAJ07783.1 - 0.0013 18.7 1.3 0.0069 16.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 OAJ07783.1 - 0.0016 18.7 0.1 0.0056 16.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 OAJ07783.1 - 0.0017 18.1 1.2 0.38 10.5 0.2 2.6 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.1 OAJ07783.1 - 0.0022 18.1 0.3 0.0055 16.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 OAJ07783.1 - 0.0066 16.1 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 OAJ07783.1 - 0.011 15.1 2.9 0.086 12.3 0.4 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 OAJ07783.1 - 0.019 14.6 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 OAJ07783.1 - 0.035 12.8 0.1 0.56 8.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 OAJ07783.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 OAJ07783.1 - 0.061 13.6 0.2 0.14 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 OAJ07783.1 - 0.065 12.6 0.6 0.44 9.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 OAJ07783.1 - 0.071 12.3 1.7 0.13 11.5 0.1 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B Pox_A32 PF04665.7 OAJ07783.1 - 0.09 12.0 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein NB-ARC PF00931.17 OAJ07783.1 - 0.091 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.12 OAJ07783.1 - 0.098 12.1 1.8 3.2 7.2 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 OAJ07783.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 OAJ07783.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Chromo PF00385.19 OAJ07783.1 - 0.12 12.0 0.1 0.39 10.4 0.0 1.9 2 0 0 2 2 1 0 Chromo (CHRromatin Organisation MOdifier) domain Sigma54_activat PF00158.21 OAJ07783.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_15 PF13175.1 OAJ07783.1 - 0.14 11.1 0.1 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF605 PF04652.11 OAJ07783.1 - 0.82 8.9 22.6 0.14 11.5 12.7 1.8 2 0 0 2 2 2 0 Vta1 like GRP PF07172.6 OAJ07784.1 - 9.2 6.8 17.5 5.1 7.6 9.8 2.2 2 0 0 2 2 2 0 Glycine rich protein family eRF1_1 PF03463.10 OAJ07786.1 - 5e-26 90.8 0.0 7.8e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 Peroxidase_2 PF01328.12 OAJ07787.1 - 4e-17 61.8 0.3 8.1e-17 60.8 0.2 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 AMP-binding PF00501.23 OAJ07788.1 - 1.5e-09 36.7 0.4 4.3e-09 35.2 0.0 1.9 2 1 0 2 2 2 1 AMP-binding enzyme Tic20 PF09685.5 OAJ07789.1 - 0.076 12.9 1.3 1 9.3 0.9 2.2 1 1 0 1 1 1 0 Tic20-like protein UPF0167 PF03691.9 OAJ07789.1 - 0.1 11.9 0.3 0.14 11.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Vma12 PF11712.3 OAJ07789.1 - 1.2 8.8 3.1 0.58 9.8 0.1 2.0 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pro_CA PF00484.14 OAJ07790.1 - 1.1e-38 132.5 0.0 1.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase ADH_N PF08240.7 OAJ07791.1 - 9.4e-26 89.7 4.4 1.4e-25 89.1 2.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 OAJ07791.1 - 1.4e-11 44.0 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 OAJ07791.1 - 0.00063 18.9 0.1 0.0014 17.7 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 OAJ07791.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 OAJ07791.1 - 0.044 13.3 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.10 OAJ07791.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.14 OAJ07791.1 - 0.065 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ribonuclease_3 PF00636.21 OAJ07792.1 - 3.6e-34 117.6 0.0 8.4e-17 61.6 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 OAJ07792.1 - 2.8e-23 81.5 0.0 7.6e-23 80.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 OAJ07792.1 - 7.3e-18 64.7 0.0 1.3e-09 38.0 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 OAJ07792.1 - 9.2e-16 57.4 0.0 2.4e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 OAJ07792.1 - 1.1e-14 54.2 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 OAJ07792.1 - 4.3e-12 46.2 0.2 8.5e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 OAJ07792.1 - 5e-07 28.8 0.2 9.1e-07 27.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain dsrm PF00035.20 OAJ07792.1 - 0.00075 20.0 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif AAA_22 PF13401.1 OAJ07792.1 - 0.0011 19.1 0.9 0.0042 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 OAJ07792.1 - 0.047 12.6 0.1 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF904 PF06005.7 OAJ07792.1 - 0.071 13.4 3.9 0.19 12.0 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Ank PF00023.25 OAJ07793.1 - 0.047 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat CAP_N PF01213.14 OAJ07793.1 - 0.068 12.4 3.1 0.2 10.9 2.1 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_3 PF13606.1 OAJ07793.1 - 0.074 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 OAJ07793.1 - 0.094 13.0 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.2 OAJ07793.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Arabinose_Iso_C PF11762.3 OAJ07794.1 - 0.073 12.6 0.4 0.13 11.8 0.3 1.3 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain RAP1 PF07218.6 OAJ07794.1 - 2.5 6.0 7.0 3.4 5.6 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Leuk-A4-hydro_C PF09127.6 OAJ07795.1 - 4.4e-46 156.0 0.0 7.3e-46 155.3 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.15 OAJ07795.1 - 2.1e-14 53.4 0.0 3.1e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 OAJ07795.1 - 6.6e-09 35.8 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily UreF PF01730.11 OAJ07796.1 - 1.5e-10 41.3 0.1 4.6e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 UreF Peptidase_M20 PF01546.23 OAJ07797.1 - 7.2e-21 74.5 0.0 1.3e-20 73.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 OAJ07797.1 - 3.1e-10 39.7 0.6 2e-09 37.1 0.4 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3953 PF13129.1 OAJ07797.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) MIP PF00230.15 OAJ07798.1 - 3.1e-38 131.5 15.6 4.2e-38 131.0 10.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein G_glu_transpept PF01019.16 OAJ07799.1 - 1.7e-138 462.3 0.5 1.6e-118 396.4 0.1 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase FMN_dh PF01070.13 OAJ07800.1 - 6.7e-106 354.1 0.1 6.7e-106 354.1 0.0 2.3 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 OAJ07800.1 - 5.5e-05 22.2 0.1 9e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 OAJ07800.1 - 0.00022 20.2 1.5 0.00061 18.7 0.8 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 OAJ07800.1 - 0.067 12.2 4.1 1.8 7.5 0.0 2.8 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG COesterase PF00135.23 OAJ07801.1 - 6.3e-99 332.0 0.0 8.6e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 OAJ07801.1 - 1.1e-09 38.1 0.7 4.2e-09 36.2 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07801.1 - 0.0032 17.2 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family NUDE_C PF04880.8 OAJ07802.1 - 2.5e-14 53.9 7.0 2.5e-14 53.9 4.8 2.9 2 1 0 2 2 1 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.3 OAJ07802.1 - 0.0013 16.1 12.9 0.0019 15.6 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.16 OAJ07802.1 - 0.0018 17.8 5.7 0.0018 17.8 3.9 2.2 1 1 1 2 2 2 1 Intermediate filament protein Syntaxin-6_N PF09177.6 OAJ07802.1 - 0.0045 17.3 13.3 0.072 13.4 1.5 3.0 3 0 0 3 3 3 2 Syntaxin 6, N-terminal DUF904 PF06005.7 OAJ07802.1 - 0.0066 16.7 4.7 0.0066 16.7 3.3 3.4 1 1 1 2 2 2 1 Protein of unknown function (DUF904) DUF948 PF06103.6 OAJ07802.1 - 0.0095 15.7 2.8 0.57 10.0 0.5 3.3 2 1 1 3 3 3 1 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 OAJ07802.1 - 0.02 14.3 13.3 0.23 10.9 0.4 3.6 2 1 1 3 3 3 0 Septum formation initiator DivIVA PF05103.8 OAJ07802.1 - 0.023 14.7 10.9 1.1 9.2 0.2 2.9 3 0 0 3 3 3 0 DivIVA protein Tox-PLDMTX PF15645.1 OAJ07802.1 - 0.12 12.3 0.6 0.25 11.4 0.4 1.4 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold TPR_MLP1_2 PF07926.7 OAJ07802.1 - 0.16 11.7 21.3 0.024 14.3 2.3 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 OAJ07802.1 - 0.16 11.7 2.4 1.3 8.7 0.7 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 OAJ07802.1 - 0.25 10.9 20.7 0.31 10.6 8.2 2.6 1 1 1 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 OAJ07802.1 - 0.53 10.0 21.2 0.3 10.8 0.5 3.9 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 OAJ07802.1 - 2.3 7.9 14.9 1.4 8.7 2.2 3.4 2 1 2 4 4 4 0 Laminin Domain II DUF972 PF06156.8 OAJ07802.1 - 3.1 8.2 17.1 1.1 9.6 1.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Viral_P18 PF04521.8 OAJ07802.1 - 3.1 7.2 10.4 2.5 7.5 0.5 3.3 2 1 1 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Reo_sigmaC PF04582.7 OAJ07802.1 - 6.1 5.9 12.6 0.32 10.1 0.9 3.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein DUF4446 PF14584.1 OAJ07802.1 - 9.4 6.0 10.2 1.4 8.7 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) Med5 PF08689.5 OAJ07803.1 - 2.4e-31 108.3 0.0 3.9e-30 104.3 0.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit Med5 Pkinase PF00069.20 OAJ07804.1 - 9.7e-60 201.9 0.0 1.1e-38 132.9 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07804.1 - 1.4e-26 93.0 0.0 7.6e-22 77.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 OAJ07804.1 - 1.8e-10 40.8 0.1 3.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 OAJ07804.1 - 3.9e-06 26.0 0.0 0.00034 19.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 OAJ07804.1 - 0.0011 18.7 0.0 0.029 14.1 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family OKR_DC_1_N PF03709.10 OAJ07804.1 - 0.0032 17.5 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain PAS_4 PF08448.5 OAJ07804.1 - 0.027 14.5 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS fold Kdo PF06293.9 OAJ07804.1 - 0.035 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 OAJ07804.1 - 0.041 12.7 0.1 0.067 12.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2730 PF10805.3 OAJ07804.1 - 0.75 9.5 0.1 2.2 8.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RIO1 PF01163.17 OAJ07804.1 - 0.76 9.0 0.0 1.9 7.7 0.0 1.5 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 OAJ07804.1 - 1.9 7.7 0.0 3.5 6.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-Sec23_Sec24 PF04810.10 OAJ07805.1 - 0.082 12.4 0.2 0.22 11.1 0.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Nop PF01798.13 OAJ07810.1 - 3.4e-55 185.4 1.1 7e-55 184.4 0.8 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 OAJ07810.1 - 6.1e-26 89.9 0.1 1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 OAJ07810.1 - 3e-10 40.1 0.1 1.2e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain IFRD_C PF04836.7 OAJ07810.1 - 0.15 12.2 2.3 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Interferon-related protein conserved region Nop16 PF09420.5 OAJ07811.1 - 5.8e-35 120.8 0.3 8.4e-35 120.2 0.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Peptidase_S3 PF00944.14 OAJ07811.1 - 0.037 13.4 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein AMP-binding PF00501.23 OAJ07821.1 - 1.9e-79 267.0 0.0 2.4e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Orn_Arg_deC_N PF02784.11 OAJ07822.1 - 3.4e-36 124.7 0.0 4.9e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 OAJ07822.1 - 2.7e-16 59.3 0.0 4.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain UQ_con PF00179.21 OAJ07823.1 - 5.8e-44 148.9 0.0 6.6e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1168 PF06658.7 OAJ07824.1 - 2.3e-37 127.6 14.5 3.6e-37 127.0 10.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF1943 PF09172.6 OAJ07825.1 - 0.064 12.1 0.0 0.077 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF1789 PF08748.6 OAJ07827.1 - 0.0015 18.6 0.4 0.81 9.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1789) Phos_pyr_kin PF08543.7 OAJ07829.1 - 4.4e-68 229.1 0.1 5.7e-51 173.0 0.0 3.2 3 0 0 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 OAJ07829.1 - 9.1e-23 81.1 0.0 1.5e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 OAJ07829.1 - 0.0034 16.6 0.7 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family Nab2 PF11517.3 OAJ07829.1 - 0.13 12.3 0.1 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) eIF-3c_N PF05470.7 OAJ07830.1 - 5.1e-181 602.7 4.6 5.1e-181 602.7 3.2 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 OAJ07830.1 - 2.7e-10 40.4 0.0 8.9e-10 38.8 0.0 2.0 1 0 0 1 1 1 1 PCI domain Daxx PF03344.10 OAJ07830.1 - 5.5 5.3 18.7 8.7 4.6 12.9 1.2 1 0 0 1 1 1 0 Daxx Family Fructosamin_kin PF03881.9 OAJ07831.1 - 1e-61 208.4 0.0 1.3e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 OAJ07831.1 - 3.7e-12 46.5 0.0 4.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_1b PF00579.20 OAJ07832.1 - 1.2e-22 80.3 0.0 3e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ABC1 PF03109.11 OAJ07833.1 - 8.5e-25 87.0 0.1 1.5e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family zf-C2H2 PF00096.21 OAJ07835.1 - 0.054 13.8 0.4 0.13 12.7 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Menin PF05053.8 OAJ07836.1 - 0.65 8.1 3.0 1.3 7.0 2.1 1.4 1 0 0 1 1 1 0 Menin Metallophos PF00149.23 OAJ07837.1 - 2.7e-43 147.6 0.1 3.4e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DAO PF01266.19 OAJ07838.1 - 8.2e-16 57.8 0.8 1.3e-13 50.6 0.5 2.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase LigB PF02900.13 OAJ07838.1 - 0.053 12.4 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Sugar_tr PF00083.19 OAJ07839.1 - 2.9e-82 276.6 24.6 3.5e-82 276.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ07839.1 - 7.8e-16 57.7 33.5 7.8e-16 57.7 23.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAH PF02671.16 OAJ07840.1 - 5.9e-44 147.4 3.9 4.9e-18 64.4 0.6 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 OAJ07840.1 - 6.1e-38 128.6 0.1 6.1e-38 128.6 0.1 2.3 3 0 0 3 3 3 1 Sin3 family co-repressor Reprolysin_5 PF13688.1 OAJ07841.1 - 0.021 14.7 1.9 0.047 13.6 1.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 OAJ07841.1 - 0.13 12.7 0.6 0.62 10.6 0.3 2.1 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 OAJ07842.1 - 2.1e-14 53.4 0.0 3.3e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 OAJ07842.1 - 1.9e-05 24.6 0.2 0.00011 22.2 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 OAJ07842.1 - 0.00019 21.9 0.1 0.0011 19.5 0.0 2.2 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ07842.1 - 0.00067 19.7 0.1 0.00096 19.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 OAJ07842.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 OAJ07842.1 - 0.047 13.2 0.1 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Acyl-CoA_dh_1 PF00441.19 OAJ07843.1 - 8.9e-35 120.0 0.3 1.2e-34 119.5 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 OAJ07843.1 - 2.4e-16 58.9 0.2 4.9e-16 57.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 OAJ07843.1 - 2.4e-12 47.4 0.3 9.5e-12 45.4 0.0 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 OAJ07843.1 - 2.2e-10 40.9 0.2 3.2e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M48 PF01435.13 OAJ07845.1 - 1.1e-36 126.5 0.0 1.3e-35 123.0 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 OAJ07845.1 - 0.013 14.5 0.0 0.013 14.5 0.0 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF4538 PF15061.1 OAJ07845.1 - 3.7 6.9 5.1 16 4.9 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4538) Abhydrolase_6 PF12697.2 OAJ07846.1 - 9.2e-23 81.3 0.1 1.2e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 OAJ07846.1 - 6.9e-10 38.8 0.4 1.2e-08 34.8 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 OAJ07846.1 - 2.6e-09 36.9 0.0 4.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 OAJ07846.1 - 0.062 12.5 0.1 0.88 8.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family ApbA_C PF08546.6 OAJ07847.1 - 1.2e-23 83.4 0.0 2.9e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 OAJ07847.1 - 5.1e-21 74.6 0.0 8.1e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 OAJ07847.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.19 OAJ07847.1 - 0.015 14.2 0.1 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 OAJ07847.1 - 0.028 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 OAJ07847.1 - 0.073 12.4 0.2 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 OAJ07847.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 OAJ07849.1 - 5.4e-09 35.9 0.0 8.1e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ07849.1 - 5.6e-09 36.3 0.0 1.8e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ07849.1 - 1.4e-07 31.9 0.0 6.5e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 OAJ07849.1 - 1.3e-05 25.9 0.1 0.00036 21.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ07849.1 - 2.4e-05 23.9 0.0 0.0008 19.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ07849.1 - 3.1e-05 23.9 0.0 9.7e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 OAJ07849.1 - 4.1e-05 24.1 0.0 0.00013 22.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.12 OAJ07849.1 - 0.0016 17.9 0.0 0.0079 15.6 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 OAJ07849.1 - 0.0041 17.4 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 OAJ07849.1 - 0.021 13.9 0.0 0.045 12.8 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MFS_1 PF07690.11 OAJ07850.1 - 1.9e-31 109.0 9.3 1.9e-31 109.0 6.5 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 OAJ07850.1 - 1.1e-06 27.5 8.9 7.1e-06 24.8 6.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 OAJ07850.1 - 4.8e-06 25.2 4.9 0.0055 15.1 0.7 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 OAJ07850.1 - 0.00055 18.2 0.3 0.00093 17.5 0.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 OAJ07852.1 - 2.1e-14 53.7 5.7 7e-10 39.0 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 OAJ07852.1 - 2.7e-08 33.6 4.4 7.2e-07 29.0 0.2 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 OAJ07852.1 - 5.1e-05 23.1 1.3 0.01 15.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 OAJ07852.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 OAJ07852.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding RabGAP-TBC PF00566.13 OAJ07853.1 - 3e-57 193.5 0.7 4.1e-57 193.1 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3166 PF11365.3 OAJ07853.1 - 0.013 15.9 0.1 0.036 14.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) CENP-F_leu_zip PF10473.4 OAJ07853.1 - 0.039 13.8 3.0 0.032 14.0 0.8 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 OAJ07853.1 - 0.18 10.8 2.4 0.37 9.7 1.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Shugoshin_N PF07558.6 OAJ07853.1 - 0.87 9.3 5.5 0.17 11.5 0.6 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region HMG_box PF00505.14 OAJ07854.1 - 8e-12 45.2 0.3 1.8e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 OAJ07854.1 - 1e-09 38.6 0.2 2.8e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain Sec63 PF02889.11 OAJ07855.1 - 1.2e-78 264.5 0.0 2.2e-78 263.6 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 OAJ07855.1 - 2.7e-42 144.1 0.6 8.1e-29 100.2 0.0 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 OAJ07855.1 - 9e-10 38.6 0.0 7.8e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 OAJ07855.1 - 4.3e-06 26.5 0.0 0.0003 20.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 OAJ07855.1 - 0.00079 19.5 0.1 0.012 15.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 OAJ07855.1 - 0.013 14.4 0.1 0.65 8.8 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 OAJ07855.1 - 0.2 10.9 0.1 21 4.2 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain UCH PF00443.24 OAJ07856.1 - 3.1e-50 170.7 0.0 1.7e-49 168.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ07856.1 - 3.3e-19 69.4 0.7 8.8e-13 48.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 OAJ07856.1 - 4.5e-07 29.8 3.4 4.5e-07 29.8 2.3 3.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.1 OAJ07856.1 - 0.88 9.9 15.0 0.3 11.4 4.6 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 OAJ07856.1 - 1.3 8.5 10.3 1.1 8.7 4.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 OAJ07856.1 - 1.4 9.2 11.2 0.87 9.8 4.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleo_P87 PF07267.6 OAJ07856.1 - 3.2 6.3 4.6 0.73 8.4 0.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.6 OAJ07856.1 - 7.2 6.4 6.5 4.3 7.1 2.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal TPR_12 PF13424.1 OAJ07857.1 - 7.7e-06 25.7 1.1 0.00021 21.1 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc5 PF12862.2 OAJ07857.1 - 0.06 13.1 0.0 0.43 10.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Myotub-related PF06602.9 OAJ07858.1 - 1e-117 392.8 0.0 5.9e-64 216.0 0.0 2.1 2 0 0 2 2 2 2 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 OAJ07858.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 OAJ07858.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 OAJ07859.1 - 1.7e-15 56.7 0.1 1e-13 50.9 0.3 2.6 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 OAJ07859.1 - 0.087 12.1 0.3 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase WD40 PF00400.27 OAJ07860.1 - 3.9e-15 55.0 0.9 0.00013 21.6 0.3 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF2407_C PF13373.1 OAJ07860.1 - 0.071 13.0 0.1 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain zf-CCHC PF00098.18 OAJ07861.1 - 1.8e-09 37.0 41.1 5.9e-07 29.1 1.1 5.7 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 OAJ07861.1 - 1.6 8.3 16.0 5 6.7 0.1 3.4 3 0 0 3 3 3 0 Zinc knuckle Smg4_UPF3 PF03467.10 OAJ07862.1 - 3.2e-32 111.9 2.9 3.2e-32 111.9 2.0 2.9 3 2 0 3 3 3 1 Smg-4/UPF3 family RRM_2 PF04059.7 OAJ07862.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 PAT1 PF09770.4 OAJ07862.1 - 5.6 5.0 60.8 3.1 5.9 33.8 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 OAJ07863.1 - 2.3e-49 165.0 6.7 2.2e-17 62.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP1_TIP1 PF00660.12 OAJ07863.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Seripauperin and TIP1 family 2-Hacid_dh_C PF02826.14 OAJ07864.1 - 1.1e-39 135.3 0.0 3e-29 101.4 0.1 2.2 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 OAJ07864.1 - 1e-24 86.5 0.0 1.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Trypsin_2 PF13365.1 OAJ07865.1 - 9.1e-07 28.8 0.0 0.0001 22.3 0.0 2.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain USP7_ICP0_bdg PF12436.3 OAJ07866.1 - 3.2e-84 282.0 0.2 6.4e-83 277.7 0.0 2.4 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 OAJ07866.1 - 2.3e-65 220.0 4.1 9.1e-65 218.0 1.4 2.7 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 OAJ07866.1 - 2.6e-54 184.1 0.1 6.2e-54 182.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 OAJ07866.1 - 8.9e-31 107.4 0.1 1.9e-30 106.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 OAJ07866.1 - 1.3e-08 35.1 0.5 3e-07 30.6 0.0 3.3 2 1 0 2 2 2 1 MATH domain Retrotrans_gag PF03732.12 OAJ07867.1 - 0.0037 17.2 0.1 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein UBN2 PF14223.1 OAJ07867.1 - 0.0045 16.7 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Peptidase_S24 PF00717.18 OAJ07868.1 - 2.3e-06 27.1 0.0 4.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 OAJ07868.1 - 0.0068 15.9 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Sugar_tr PF00083.19 OAJ07871.1 - 3.2e-48 164.4 14.3 3.8e-48 164.1 9.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 OAJ07871.1 - 4.5e-24 84.8 22.4 1.5e-14 53.5 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 OAJ07871.1 - 0.1 10.6 2.8 0.084 10.9 0.1 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RabGAP-TBC PF00566.13 OAJ07873.1 - 1.6e-49 168.3 0.0 2.4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain OmpH PF03938.9 OAJ07873.1 - 0.0014 18.5 1.5 0.65 9.9 0.3 2.4 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Nucleo_P87 PF07267.6 OAJ07873.1 - 0.0041 15.8 1.1 0.012 14.3 0.7 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 TUDOR PF00567.19 OAJ07874.1 - 0.00029 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 OAJ07874.1 - 0.0057 15.7 0.0 0.0057 15.7 0.0 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) Rotamase_2 PF13145.1 OAJ07874.1 - 0.054 14.1 3.2 0.43 11.2 0.9 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain Med3 PF11593.3 OAJ07874.1 - 0.089 12.0 5.2 0.13 11.4 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LBR_tudor PF09465.5 OAJ07874.1 - 0.092 12.3 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain GTP_EFTU PF00009.22 OAJ07877.1 - 5.9e-51 172.5 0.0 1e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 OAJ07877.1 - 1.1e-13 50.8 0.0 2.3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 OAJ07877.1 - 7.4e-09 35.3 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 OAJ07877.1 - 4.2e-05 23.5 0.0 0.00019 21.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 OAJ07877.1 - 0.0046 16.5 0.0 0.031 13.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 OAJ07877.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M43 PF05572.8 OAJ07878.1 - 1.8e-19 69.8 0.1 3.4e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 OAJ07878.1 - 1.6e-07 31.8 0.1 1.6e-07 31.8 0.1 2.0 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 OAJ07878.1 - 1.2e-05 25.4 3.7 1.7e-05 24.9 2.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 OAJ07878.1 - 1.2e-05 25.3 4.4 1.6e-05 24.8 3.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 OAJ07878.1 - 0.0011 18.5 4.1 0.002 17.6 2.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 OAJ07878.1 - 0.0026 17.4 1.1 0.0026 17.4 0.8 2.0 2 0 0 2 2 2 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 OAJ07878.1 - 0.0049 16.6 0.2 0.0075 16.0 0.2 1.4 1 1 0 1 1 1 1 Matrixin BHD_3 PF10405.4 OAJ07878.1 - 0.032 13.9 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 zf-B_box PF00643.19 OAJ07880.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.7 2 1 0 2 2 2 0 B-box zinc finger zf-C2H2 PF00096.21 OAJ07880.1 - 2.6 8.5 5.4 4.4 7.8 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 OAJ07880.1 - 3.9 7.2 6.8 1.4 8.6 1.0 2.4 1 1 1 2 2 2 0 zinc-finger of a C2HC-type C1_1 PF00130.17 OAJ07880.1 - 6.9 6.4 8.9 2 8.1 0.7 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-dskA_traR PF01258.12 OAJ07880.1 - 8.1 6.2 11.0 3 7.6 0.1 4.0 5 0 0 5 5 5 0 Prokaryotic dksA/traR C4-type zinc finger DUF3759 PF12585.3 OAJ07881.1 - 1.8e-39 133.5 8.3 2.1e-39 133.3 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.3 OAJ07882.1 - 1.2e-40 137.2 9.0 1.4e-40 137.0 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RRM_6 PF14259.1 OAJ07883.1 - 1.1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 OAJ07883.1 - 0.0031 17.1 0.0 0.0072 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 OAJ07883.1 - 1.7 6.4 16.8 3.8 5.3 11.7 1.7 1 0 0 1 1 1 0 Nop14-like family FAM72 PF14976.1 OAJ07884.1 - 6.1e-21 74.8 0.4 1.3e-20 73.7 0.2 1.5 2 0 0 2 2 2 1 FAM72 protein LMBR1 PF04791.11 OAJ07884.1 - 0.24 9.9 0.2 0.3 9.6 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein cNMP_binding PF00027.24 OAJ07885.1 - 1.5e-37 127.3 0.0 2.2e-17 62.6 0.0 5.5 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 OAJ07885.1 - 2.3e-18 66.8 4.7 1.5e-11 44.6 1.6 3.2 3 0 0 3 3 3 2 Patatin-like phospholipase IL28A PF15177.1 OAJ07885.1 - 0.36 10.3 0.0 0.71 9.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin-28A Ytp1 PF10355.4 OAJ07886.1 - 2.2e-87 292.7 3.5 3.1e-87 292.2 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 OAJ07886.1 - 2.6e-17 62.3 5.4 2.9e-17 62.1 0.4 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Lin-8 PF03353.10 OAJ07886.1 - 9.6 5.3 5.0 19 4.4 3.5 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist AlaDh_PNT_N PF05222.10 OAJ07887.1 - 4.1e-27 94.8 0.0 6.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 OAJ07887.1 - 3.5e-07 29.9 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiC-associated PF13667.1 OAJ07887.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain Cyclin_N PF00134.18 OAJ07888.1 - 0.00048 19.6 0.1 0.00048 19.6 0.1 2.5 3 0 0 3 3 3 1 Cyclin, N-terminal domain RFX_DNA_binding PF02257.10 OAJ07889.1 - 6e-20 71.1 0.2 1.2e-19 70.1 0.2 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Nop14 PF04147.7 OAJ07889.1 - 0.0015 16.5 5.9 0.0024 15.8 4.1 1.3 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 OAJ07889.1 - 0.19 10.9 10.2 0.35 10.1 7.1 1.4 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 OAJ07889.1 - 0.43 10.1 8.5 0.9 9.0 5.9 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 OAJ07889.1 - 0.97 7.3 7.8 1.5 6.7 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein BTB PF00651.26 OAJ07890.1 - 0.0013 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ABC_membrane PF00664.18 OAJ07891.1 - 1.4e-45 155.9 2.8 1.9e-45 155.3 1.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 OAJ07891.1 - 3.9e-31 108.1 0.0 1.3e-30 106.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 OAJ07891.1 - 0.00022 21.2 0.0 0.032 14.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 OAJ07891.1 - 0.00022 21.2 0.2 0.00079 19.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 OAJ07891.1 - 0.001 18.2 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 OAJ07891.1 - 0.002 17.3 0.2 0.058 12.6 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 OAJ07891.1 - 0.0021 18.2 0.0 0.013 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF637 PF04830.8 OAJ07891.1 - 0.0038 16.9 0.2 0.0098 15.5 0.2 1.7 1 0 0 1 1 1 1 Possible hemagglutinin (DUF637) AAA_5 PF07728.9 OAJ07891.1 - 0.012 15.3 0.1 0.6 9.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 OAJ07891.1 - 0.026 13.1 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.1 OAJ07891.1 - 0.031 13.8 0.0 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 OAJ07891.1 - 0.039 14.1 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 OAJ07891.1 - 0.07 12.8 0.0 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 OAJ07891.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 OAJ07891.1 - 0.13 12.2 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 OAJ07891.1 - 0.17 12.7 0.0 0.34 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.6 OAJ07892.1 - 3.7e-05 23.5 28.5 0.0016 18.1 19.7 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 BMF PF15185.1 OAJ07892.1 - 0.0051 16.1 1.0 0.0051 16.1 0.7 1.7 2 1 1 3 3 3 1 Bcl-2-modifying factor, apoptosis NPR2 PF06218.6 OAJ07893.1 - 3.6e-103 345.5 0.2 1.5e-47 162.2 0.2 4.9 3 2 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.8 OAJ07893.1 - 0.12 10.8 0.0 0.12 10.8 0.0 3.1 3 1 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_M28 PF04389.12 OAJ07894.1 - 1.9e-33 115.6 0.0 2.8e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 OppC_N PF12911.2 OAJ07894.1 - 0.026 13.8 0.7 0.064 12.6 0.5 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4520 PF15016.1 OAJ07894.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) zf-H2C2_2 PF13465.1 OAJ07896.1 - 1.2e-25 88.4 28.6 1.3e-07 31.5 0.4 7.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 OAJ07896.1 - 5.5e-17 61.0 46.7 0.00045 20.4 0.1 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 OAJ07896.1 - 1.5e-09 37.5 47.9 0.0071 16.6 0.1 9.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 OAJ07896.1 - 0.011 15.6 12.8 1.9 8.4 0.5 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger p450 PF00067.17 OAJ07897.1 - 1.3e-55 188.7 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ07898.1 - 5.2e-54 183.5 0.0 6.5e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ07899.1 - 1.6e-52 178.6 0.0 2e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 OAJ07900.1 - 1.7e-103 346.6 0.0 4.3e-53 180.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 VASP_tetra PF08776.6 OAJ07900.1 - 0.11 11.8 0.1 0.36 10.1 0.1 1.8 1 0 0 1 1 1 0 VASP tetramerisation domain UQ_con PF00179.21 OAJ07901.1 - 1.6e-22 79.4 0.0 1.8e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 OAJ07901.1 - 0.0092 15.7 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B AAA PF00004.24 OAJ07903.1 - 3.1e-14 53.3 0.0 6.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 OAJ07903.1 - 8.2e-13 48.3 0.0 3.2e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 OAJ07903.1 - 3e-08 33.8 0.0 1.1e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rep_fac_C PF08542.6 OAJ07903.1 - 1.9e-07 30.9 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 OAJ07903.1 - 3.5e-06 25.9 0.0 0.00064 18.5 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 OAJ07903.1 - 1.5e-05 24.6 0.2 6.7e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 OAJ07903.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 OAJ07903.1 - 0.00022 21.2 1.0 0.014 15.4 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 OAJ07903.1 - 0.00046 19.8 0.0 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 OAJ07903.1 - 0.00064 19.7 0.1 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 OAJ07903.1 - 0.00069 19.1 0.0 0.0022 17.5 0.0 1.8 1 1 1 2 2 2 1 DEAD/DEAH box helicase RuvB_N PF05496.7 OAJ07903.1 - 0.00071 18.6 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 OAJ07903.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 OAJ07903.1 - 0.0055 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 OAJ07903.1 - 0.0085 15.2 0.0 0.036 13.2 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 OAJ07903.1 - 0.026 13.9 0.3 0.12 11.7 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 OAJ07903.1 - 0.027 14.0 0.3 0.059 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 OAJ07903.1 - 0.028 13.8 0.1 0.12 11.8 0.0 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 OAJ07903.1 - 0.062 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 OAJ07903.1 - 0.066 12.9 0.5 0.65 9.7 0.3 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 OAJ07903.1 - 0.083 12.3 0.1 1.5 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain MCM PF00493.18 OAJ07903.1 - 0.11 11.3 0.3 4 6.1 0.0 2.7 3 0 0 3 3 3 0 MCM2/3/5 family TrwB_AAD_bind PF10412.4 OAJ07903.1 - 0.13 10.8 0.0 0.26 9.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PfkB PF00294.19 OAJ07905.1 - 1.4e-34 119.5 0.8 1.8e-34 119.2 0.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HECT PF00632.20 OAJ07906.1 - 2.6e-96 322.5 0.0 3.3e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DIE2_ALG10 PF04922.7 OAJ07911.1 - 3.1e-99 332.5 10.1 4.8e-75 252.9 5.3 2.0 2 0 0 2 2 2 2 DIE2/ALG10 family Band_7 PF01145.20 OAJ07911.1 - 0.045 13.6 0.3 0.19 11.5 0.2 1.9 2 0 0 2 2 2 0 SPFH domain / Band 7 family ADH_zinc_N PF00107.21 OAJ07912.1 - 6e-20 71.1 0.8 1.1e-19 70.3 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 OAJ07912.1 - 5.7e-09 36.9 0.2 1.1e-08 36.0 0.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 OAJ07912.1 - 0.005 16.5 0.1 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 OAJ07912.1 - 0.12 12.4 0.3 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3835 PF12927.2 OAJ07913.1 - 0.00011 23.0 18.5 0.0005 20.9 0.0 4.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) Nop14 PF04147.7 OAJ07913.1 - 0.077 10.9 20.6 0.13 10.1 14.3 1.3 1 0 0 1 1 1 0 Nop14-like family Histone_HNS PF00816.16 OAJ07913.1 - 1.3 9.5 6.1 0.6 10.6 0.6 3.0 2 1 0 2 2 2 0 H-NS histone family DUF4347 PF14252.1 OAJ07914.1 - 0.15 11.5 6.5 0.21 11.0 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) PLRV_ORF5 PF01690.12 OAJ07914.1 - 0.48 9.5 6.8 0.56 9.2 4.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Nramp PF01566.13 OAJ07915.1 - 4e-88 295.5 21.3 2.3e-49 168.1 5.8 2.4 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein Ank_2 PF12796.2 OAJ07916.1 - 8.4e-28 96.5 3.0 2.2e-12 47.1 0.1 2.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 OAJ07916.1 - 3.7e-16 59.1 0.9 8.7e-12 45.2 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 OAJ07916.1 - 1.7e-15 55.9 3.0 4.5e-09 35.6 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 OAJ07916.1 - 1.8e-12 46.2 1.4 8.9e-06 25.4 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 OAJ07916.1 - 5.7e-09 35.9 5.1 7.1e-06 26.0 0.3 4.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DJ-1_PfpI PF01965.19 OAJ07917.1 - 1.8e-27 95.5 0.1 3.5e-27 94.6 0.1 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 OAJ07917.1 - 3.5e-17 61.6 0.0 6.1e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Ferric_reduct PF01794.14 OAJ07918.1 - 3.8e-16 59.3 11.5 3.8e-16 59.3 7.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 OAJ07918.1 - 6.9e-13 48.7 0.0 1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 OAJ07918.1 - 2.3e-06 27.4 0.0 0.0011 18.7 0.0 2.7 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 OAJ07918.1 - 0.016 15.8 0.0 1.7 9.2 0.0 2.8 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1682 PF07946.9 OAJ07919.1 - 1.7e-51 174.9 0.0 2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Xan_ur_permease PF00860.15 OAJ07919.1 - 0.028 12.9 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Permease family Nucleoporin_C PF03177.9 OAJ07920.1 - 1.5e-55 188.8 10.5 2.3e-55 188.2 7.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 OAJ07920.1 - 6.9e-14 51.4 0.0 1.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Nup133 N terminal like DASH_Spc19 PF08287.6 OAJ07920.1 - 3 7.4 10.9 2.5 7.6 5.8 2.0 2 0 0 2 2 2 0 Spc19 Peptidase_M22 PF00814.20 OAJ07921.1 - 1.8e-75 253.9 0.2 2.3e-74 250.2 0.1 2.0 1 1 0 1 1 1 1 Glycoprotease family FancD2 PF14631.1 OAJ07922.1 - 0.022 11.9 0.0 0.033 11.3 0.0 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SAM_PNT PF02198.11 OAJ07922.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain F-box PF00646.28 OAJ07923.1 - 0.0001 21.8 0.1 0.00021 20.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ07923.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 OAJ07924.1 - 3.2e-06 26.6 0.6 3.2e-06 26.6 0.4 1.8 2 0 0 2 2 2 1 F-box domain MIF4G PF02854.14 OAJ07925.1 - 2e-54 184.1 0.0 9e-31 106.9 0.0 3.8 3 1 1 4 4 4 3 MIF4G domain Upf2 PF04050.9 OAJ07925.1 - 7.6e-24 84.3 15.0 2.5e-23 82.7 10.4 1.9 1 0 0 1 1 1 1 Up-frameshift suppressor 2 TFIIF_alpha PF05793.7 OAJ07925.1 - 0.02 13.2 16.0 0.041 12.2 11.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 OAJ07925.1 - 0.35 8.8 19.0 0.81 7.6 13.0 1.7 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 OAJ07925.1 - 0.57 9.5 15.8 1.2 8.4 11.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 OAJ07925.1 - 1.2 9.1 7.2 3.8 7.5 5.0 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 OAJ07925.1 - 1.3 6.9 29.8 3.1 5.5 20.6 1.6 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 OAJ07925.1 - 4.3 5.6 30.4 0.07 11.6 15.6 1.8 2 0 0 2 2 2 0 Daxx Family VRR_NUC PF08774.6 OAJ07926.1 - 3.6e-16 59.0 0.0 9.1e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain MOZ_SAS PF01853.13 OAJ07927.1 - 9.5e-79 263.0 0.1 1.4e-78 262.4 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family SOG2 PF10428.4 OAJ07928.1 - 8.7e-66 222.4 0.1 8.7e-66 222.4 0.1 5.2 3 2 1 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 OAJ07928.1 - 8.4e-15 54.0 0.6 2e-07 30.4 0.0 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ07928.1 - 2.1e-13 49.8 0.1 1.1e-08 34.7 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ07928.1 - 3.7e-06 26.2 0.1 2.1 8.7 0.0 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 OAJ07928.1 - 0.00069 19.4 0.1 22 5.8 0.0 4.8 4 0 0 4 4 4 1 Leucine rich repeat F-box PF00646.28 OAJ07929.1 - 5.4e-08 32.3 0.2 1.1e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ07929.1 - 0.046 13.4 0.2 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 OAJ07929.1 - 0.089 12.5 0.7 0.42 10.3 0.5 2.1 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 OAJ07930.1 - 3.7e-08 32.8 0.1 6.6e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ07930.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Tfb4 PF03850.9 OAJ07931.1 - 5.3e-52 176.7 7.6 4e-28 98.4 0.0 3.8 1 1 1 2 2 2 2 Transcription factor Tfb4 XRCC4 PF06632.7 OAJ07931.1 - 0.052 12.3 0.2 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cmc1 PF08583.5 OAJ07932.1 - 1.2e-16 60.1 1.0 1.7e-16 59.7 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 OAJ07932.1 - 0.51 10.3 3.0 1.8 8.5 2.1 1.9 1 1 0 1 1 1 0 CHCH domain RasGAP_C PF03836.10 OAJ07933.1 - 3.5e-23 81.8 0.0 3.5e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 RasGAP C-terminus Tfb4 PF03850.9 OAJ07933.1 - 1.8e-18 66.7 8.4 1.8e-18 66.7 5.8 2.9 2 1 1 3 3 3 1 Transcription factor Tfb4 DEAD PF00270.24 OAJ07933.1 - 1.2e-16 60.7 0.0 9.7e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Thg1 PF04446.7 OAJ07934.1 - 2.8e-44 150.0 0.0 4.8e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 OAJ07934.1 - 6.8e-44 148.4 0.1 1e-43 147.8 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Pheromone PF08015.6 OAJ07934.1 - 0.26 12.1 1.3 5.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone CPSF73-100_C PF11718.3 OAJ07935.1 - 1.8e-47 161.5 0.7 1.5e-45 155.1 0.9 2.9 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 OAJ07935.1 - 8.6e-31 106.5 0.0 1.8e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 OAJ07935.1 - 9.6e-14 51.4 5.8 1.2e-13 51.1 0.2 2.6 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 OAJ07935.1 - 9.8e-11 41.3 0.1 1.9e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 OAJ07935.1 - 2.2e-10 40.4 0.2 5.2e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 OAJ07935.1 - 1.1e-06 28.4 0.0 3.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Rad60-SLD PF11976.3 OAJ07937.1 - 0.003 17.2 0.0 1.2 8.9 0.0 3.6 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like DEAD PF00270.24 OAJ07938.1 - 1.2e-28 99.7 0.0 1.6e-13 50.5 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 OAJ07938.1 - 8.7e-21 73.5 0.1 1.8e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 OAJ07938.1 - 0.0032 17.3 0.0 0.0085 15.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Phage_lysis PF03245.8 OAJ07939.1 - 0.0019 18.1 1.9 0.0019 18.1 1.3 2.4 1 1 1 2 2 2 1 Bacteriophage Rz lysis protein CASP_C PF08172.7 OAJ07939.1 - 0.04 12.9 10.8 0.057 12.4 7.5 1.3 1 1 0 1 1 1 0 CASP C terminal DUF2653 PF10850.3 OAJ07939.1 - 0.067 13.4 0.2 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) ACR_tran PF00873.14 OAJ07939.1 - 0.29 8.4 7.0 0.35 8.2 4.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TPR_MLP1_2 PF07926.7 OAJ07939.1 - 0.43 10.3 16.7 0.03 14.0 4.9 2.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.4 OAJ07939.1 - 0.72 9.4 7.8 1.6 8.3 3.2 2.8 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2422 PF10337.4 OAJ07939.1 - 7.9 5.1 9.7 7.2 5.2 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Complex1_LYR PF05347.10 OAJ07940.1 - 0.0033 17.2 0.5 0.0033 17.2 0.4 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 OAJ07940.1 - 0.35 11.1 4.2 0.16 12.1 0.4 2.3 2 1 1 3 3 3 0 Complex1_LYR-like Dor1 PF04124.7 OAJ07941.1 - 0.022 13.2 5.2 0.22 9.9 1.2 2.3 2 0 0 2 2 2 0 Dor1-like family G-patch PF01585.18 OAJ07942.1 - 1.2e-05 24.9 1.9 1.4e-05 24.7 0.2 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.3 OAJ07942.1 - 0.0069 16.4 2.3 0.011 15.8 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 OAJ07942.1 - 0.097 12.9 0.3 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3449 PF11931.3 OAJ07942.1 - 3.5 7.0 10.8 0.096 12.1 0.9 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3449) Kelch_4 PF13418.1 OAJ07943.1 - 1.2e-42 143.3 14.2 2.4e-07 30.3 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 OAJ07943.1 - 3.2e-33 113.1 15.1 2.1e-08 34.0 0.3 7.3 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 OAJ07943.1 - 2.9e-29 100.3 5.4 1e-05 24.9 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 OAJ07943.1 - 4.8e-25 87.0 12.8 2.8e-06 27.1 0.2 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 OAJ07943.1 - 3.2e-23 80.5 9.4 5.2e-05 22.8 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 OAJ07943.1 - 1.4e-21 75.6 11.0 0.00015 21.7 0.0 6.7 6 1 1 7 7 7 5 Kelch motif PQQ_3 PF13570.1 OAJ07943.1 - 1.2 9.5 6.1 7.9 6.9 0.0 4.7 6 0 0 6 6 6 0 PQQ-like domain HABP4_PAI-RBP1 PF04774.10 OAJ07944.1 - 0.00043 20.7 5.2 0.00043 20.7 3.6 2.7 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family Cyclin_N PF00134.18 OAJ07945.1 - 3.4e-09 36.3 0.0 5.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 OAJ07945.1 - 0.017 15.0 0.1 0.5 10.3 0.0 2.5 2 0 0 2 2 2 0 Cyclin, C-terminal domain Pep3_Vps18 PF05131.9 OAJ07946.1 - 1.2e-42 144.7 0.0 5.1e-42 142.7 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 OAJ07946.1 - 1.2e-06 28.1 8.8 4.5e-06 26.3 0.4 2.7 2 1 0 2 2 2 2 Region in Clathrin and VPS Terminase_5 PF06056.7 OAJ07946.1 - 0.0066 15.9 0.7 0.016 14.7 0.5 1.7 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) zf-RING_2 PF13639.1 OAJ07946.1 - 0.0094 15.7 2.8 0.0094 15.7 1.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 OAJ07946.1 - 0.015 14.9 1.0 0.037 13.7 0.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PPR_3 PF13812.1 OAJ07946.1 - 0.017 15.3 0.1 14 6.2 0.1 3.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Vps39_2 PF10367.4 OAJ07946.1 - 0.044 13.9 0.2 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 OAJ07946.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_11 PF13414.1 OAJ07946.1 - 1.4 8.5 4.9 7.6 6.2 0.0 3.6 3 1 1 4 4 4 0 TPR repeat Ribosomal_S3_C PF00189.15 OAJ07948.1 - 1.3e-16 60.5 0.1 2.3e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 OAJ07948.1 - 2.2e-09 36.7 0.0 3.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_S9 PF00380.14 OAJ07949.1 - 2.5e-38 131.0 0.4 3.4e-38 130.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TPMT PF05724.6 OAJ07950.1 - 4.7e-33 114.4 0.1 6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 OAJ07950.1 - 2.2e-10 41.1 0.0 4.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 OAJ07950.1 - 8e-10 38.5 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 OAJ07950.1 - 1e-09 38.7 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 OAJ07950.1 - 3.5e-07 30.2 0.3 1.5e-06 28.2 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 OAJ07950.1 - 7.6e-07 29.5 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 OAJ07950.1 - 2.9e-06 27.0 0.0 4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 OAJ07950.1 - 3.3e-06 27.3 0.0 5.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 OAJ07950.1 - 0.0037 16.4 0.1 0.013 14.6 0.0 1.8 1 1 1 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.14 OAJ07950.1 - 0.042 13.3 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 OAJ07950.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PfkB PF00294.19 OAJ07951.1 - 6.7e-06 25.4 0.1 0.00012 21.3 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Clathrin_bdg PF15045.1 OAJ07952.1 - 0.1 12.1 0.2 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Clathrin-binding box of Aftiphilin, vesicle trafficking AAA PF00004.24 OAJ07953.1 - 3.4e-17 62.8 0.0 1e-16 61.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 OAJ07953.1 - 8.2e-17 60.9 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 OAJ07953.1 - 4.5e-16 58.9 0.0 4.4e-14 52.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 OAJ07953.1 - 3.7e-11 42.4 0.0 1.8e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 OAJ07953.1 - 3.2e-06 27.3 0.2 0.001 19.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 OAJ07953.1 - 1.3e-05 24.3 0.0 2.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 OAJ07953.1 - 3.2e-05 23.8 0.0 9.7e-05 22.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 OAJ07953.1 - 4.2e-05 22.6 0.0 6.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 OAJ07953.1 - 4.5e-05 23.1 0.1 0.004 16.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 OAJ07953.1 - 4.6e-05 23.1 0.1 0.0002 21.0 0.0 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 OAJ07953.1 - 5.5e-05 22.7 0.0 0.00014 21.4 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 OAJ07953.1 - 0.00011 22.2 0.0 0.0031 17.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 OAJ07953.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.8 1 1 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 OAJ07953.1 - 0.00027 20.5 0.0 0.00056 19.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 OAJ07953.1 - 0.00037 20.0 0.3 0.39 10.1 0.0 2.3 1 1 0 2 2 2 2 AAA-like domain AAA_25 PF13481.1 OAJ07953.1 - 0.0012 18.2 0.0 0.0072 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 OAJ07953.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 OAJ07953.1 - 0.0021 17.6 0.0 0.0068 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 OAJ07953.1 - 0.0099 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 OAJ07953.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 OAJ07953.1 - 0.024 14.1 0.2 0.3 10.5 0.0 2.4 2 1 1 3 3 2 0 DEAD/DEAH box helicase T2SE PF00437.15 OAJ07953.1 - 0.025 13.4 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 OAJ07953.1 - 0.025 14.0 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 OAJ07953.1 - 0.033 14.0 0.0 0.22 11.3 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 OAJ07953.1 - 0.045 13.1 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 OAJ07953.1 - 0.051 13.8 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 OAJ07953.1 - 0.094 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 OAJ07953.1 - 0.1 11.7 0.0 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 OAJ07953.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2418 PF10332.4 OAJ07955.1 - 9.1e-20 70.8 1.2 9.1e-20 70.8 0.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Nop14 PF04147.7 OAJ07955.1 - 6e-05 21.1 19.6 7.2e-05 20.9 13.6 1.1 1 0 0 1 1 1 1 Nop14-like family Trypan_PARP PF05887.6 OAJ07955.1 - 2.8 7.7 30.2 1.4 8.7 16.3 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RNA_pol_3_Rpc31 PF11705.3 OAJ07955.1 - 4.5 7.1 27.5 13 5.5 19.1 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Daxx PF03344.10 OAJ07955.1 - 5 5.4 30.2 8.1 4.7 21.0 1.2 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 OAJ07955.1 - 8.4 5.4 33.8 14 4.7 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_M1 PF01433.15 OAJ07956.1 - 1.2e-104 350.4 0.0 1.6e-66 225.0 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 OAJ07956.1 - 5.1e-58 196.8 0.0 8.6e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAJ07956.1 - 8.4e-15 54.9 0.1 2.5e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily Rhodopsin_N PF10413.4 OAJ07957.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin DUF3899 PF13038.1 OAJ07958.1 - 0.04 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Med6 PF04934.9 OAJ07959.1 - 4.2e-42 143.0 0.0 5e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Nucleoplasmin PF03066.10 OAJ07959.1 - 0.0021 17.5 0.2 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin Sigma70_ner PF04546.8 OAJ07959.1 - 0.13 11.8 1.5 0.19 11.3 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 OAJ07959.1 - 0.17 12.1 5.2 0.32 11.3 3.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 OAJ07959.1 - 0.56 8.8 6.0 0.8 8.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 OAJ07959.1 - 1.5 7.9 3.4 2.2 7.4 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 OAJ07959.1 - 3.9 7.7 10.4 9.3 6.5 7.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rad10 PF03834.9 OAJ07960.1 - 9.1e-31 105.3 0.1 1.7e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 OAJ07960.1 - 3.8e-08 33.3 0.0 8.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 OAJ07960.1 - 0.00034 20.4 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif Trypan_PARP PF05887.6 OAJ07960.1 - 0.095 12.5 6.6 0.2 11.4 4.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tht1 PF04163.7 OAJ07961.1 - 0.0013 17.1 0.3 0.0013 17.1 0.2 1.9 1 1 1 2 2 2 1 Tht1-like nuclear fusion protein YbjQ_1 PF01906.12 OAJ07961.1 - 0.28 11.6 2.7 1.1 9.7 0.3 2.4 2 0 0 2 2 2 0 Putative heavy-metal-binding Nnf1 PF03980.9 OAJ07962.1 - 8.2e-05 22.5 5.7 8.2e-05 22.5 4.0 2.3 2 1 0 2 2 2 1 Nnf1 2_5_RNA_ligase2 PF13563.1 OAJ07962.1 - 0.018 14.7 2.7 0.2 11.3 1.0 2.8 1 1 1 2 2 2 0 2'-5' RNA ligase superfamily Pox_A_type_inc PF04508.7 OAJ07962.1 - 0.065 13.0 1.3 0.41 10.5 0.9 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat TPR_MLP1_2 PF07926.7 OAJ07962.1 - 0.17 11.5 21.5 0.1 12.3 3.8 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Herpes_UL6 PF01763.11 OAJ07962.1 - 0.39 8.8 10.4 0.006 14.8 1.8 1.7 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF972 PF06156.8 OAJ07962.1 - 1.4 9.3 14.1 2.8 8.3 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF724 PF05266.9 OAJ07962.1 - 1.8 8.1 16.6 2.4 7.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.4 OAJ07962.1 - 4.3 6.2 17.7 2.9 6.7 6.5 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4094 PF13334.1 OAJ07962.1 - 4.4 7.7 10.2 0.67 10.3 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Spore_coat_CotO PF14153.1 OAJ07962.1 - 6.8 6.0 15.9 3.9 6.8 2.6 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Mod_r PF07200.8 OAJ07962.1 - 8.7 6.2 21.9 0.057 13.3 4.9 2.7 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1223 PF06764.6 OAJ07962.1 - 9.1 6.0 8.6 0.66 9.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) Zn_clus PF00172.13 OAJ07963.1 - 9.2e-06 25.4 7.2 1.5e-05 24.7 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain rRNA_processing PF08524.6 OAJ07964.1 - 3.1e-06 27.0 0.7 3.1e-06 27.0 0.5 4.0 3 1 0 3 3 3 1 rRNA processing Daxx PF03344.10 OAJ07964.1 - 0.085 11.3 20.5 0.11 10.9 14.2 1.1 1 0 0 1 1 1 0 Daxx Family His_Phos_2 PF00328.17 OAJ07965.1 - 0.00025 20.5 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MFS_1 PF07690.11 OAJ07966.1 - 6.8e-21 74.3 33.3 4.2e-17 61.9 8.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 OAJ07966.1 - 1.6e-05 23.6 19.8 1.9e-05 23.3 4.1 2.5 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DUF3270 PF11674.3 OAJ07966.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3270) LRR_4 PF12799.2 OAJ07967.1 - 1.2e-14 53.5 7.9 1.2e-05 24.7 2.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 OAJ07967.1 - 8e-14 51.1 9.8 1.6e-08 34.1 3.4 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 OAJ07967.1 - 1.7e-05 24.1 13.7 0.81 9.9 0.1 5.6 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 OAJ07967.1 - 0.19 12.0 15.7 8.7 7.0 0.2 5.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 OAJ07967.1 - 2.2 8.6 10.2 11 6.4 0.1 4.4 4 1 1 5 5 5 0 Leucine Rich repeat EHN PF06441.7 OAJ07968.1 - 1e-22 80.1 0.0 2.4e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 OAJ07968.1 - 1.2e-11 44.6 0.1 2.7e-10 40.2 0.0 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 OAJ07968.1 - 2.1e-09 37.6 5.0 2e-08 34.4 2.2 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 OAJ07968.1 - 0.00023 21.2 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Mg_trans_NIPA PF05653.9 OAJ07969.1 - 1.8e-26 92.7 7.8 2.7e-13 49.5 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA GSK-3_bind PF05350.7 OAJ07969.1 - 0.008 15.6 0.4 0.008 15.6 0.3 3.3 3 0 0 3 3 3 1 Glycogen synthase kinase-3 binding EamA PF00892.15 OAJ07969.1 - 0.023 14.7 25.3 0.017 15.1 4.7 3.2 3 0 0 3 3 3 0 EamA-like transporter family Tetraspannin PF00335.15 OAJ07969.1 - 0.76 9.0 15.0 0.75 9.0 0.4 2.7 2 1 1 3 3 3 0 Tetraspanin family Neurensin PF14927.1 OAJ07969.1 - 0.79 9.1 2.8 21 4.5 0.2 2.6 2 0 0 2 2 2 0 Neurensin EmrE PF13536.1 OAJ07969.1 - 1.9 8.6 31.6 0.11 12.6 6.3 3.4 2 1 1 3 3 3 0 Multidrug resistance efflux transporter Pkinase PF00069.20 OAJ07970.1 - 2.7e-49 167.6 0.0 1.1e-46 159.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 OAJ07970.1 - 6.5e-17 61.4 0.0 2.5e-15 56.2 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 OAJ07970.1 - 0.00045 19.2 0.0 0.00078 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 OAJ07970.1 - 0.00081 19.1 0.3 0.0025 17.5 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 OAJ07970.1 - 0.0014 17.7 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RasGAP PF00616.14 OAJ07972.1 - 2.3e-54 184.0 0.0 5.2e-54 182.8 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 OAJ07972.1 - 1.3e-39 135.0 0.2 3.8e-39 133.6 0.2 1.8 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 OAJ07972.1 - 0.012 15.9 0.6 4.8 7.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RF-1 PF00472.15 OAJ07974.1 - 6.7e-38 128.9 1.9 6.7e-38 128.9 1.3 1.9 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 OAJ07974.1 - 1.7e-33 114.7 0.1 1.2e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 PCRF domain Mu-like_Com PF10122.4 OAJ07974.1 - 0.025 13.6 0.0 0.074 12.1 0.0 1.8 1 0 0 1 1 1 0 Mu-like prophage protein Com YL1 PF05764.8 OAJ07975.1 - 4.2e-39 134.5 21.5 6.5e-39 133.9 14.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 OAJ07975.1 - 1.2e-09 37.5 0.0 1.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain SET PF00856.23 OAJ07976.1 - 1.3e-22 80.7 1.1 1.1e-21 77.8 0.0 2.8 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 OAJ07976.1 - 1.5e-14 54.0 6.5 1.5e-14 54.0 4.5 2.1 2 0 0 2 2 2 1 Pre-SET motif Myb_DNA-binding PF00249.26 OAJ07977.1 - 3.8e-13 49.2 3.9 2.3e-08 33.9 0.4 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 OAJ07977.1 - 2.2e-11 43.6 5.3 1.6e-09 37.7 0.1 3.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Peptidase_M19 PF01244.16 OAJ07978.1 - 1.9e-95 319.4 0.0 2.2e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Myb_DNA-binding PF00249.26 OAJ07979.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Aa_trans PF01490.13 OAJ07980.1 - 3.2e-73 246.5 21.3 4.3e-73 246.1 14.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 OAJ07980.1 - 0.00016 20.6 18.9 0.00045 19.1 13.1 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family PI31_Prot_N PF11566.3 OAJ07981.1 - 1.9e-33 115.2 0.0 2.4e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 OAJ07981.1 - 8.3e-15 55.1 16.9 8.3e-15 55.1 11.7 3.5 3 1 1 4 4 4 1 PI31 proteasome regulator F-box-like PF12937.2 OAJ07982.1 - 0.0018 17.9 0.2 0.0064 16.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ07982.1 - 0.059 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 F-box domain RHH_2 PF03693.9 OAJ07983.1 - 0.0068 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0156) DUF3960 PF13142.1 OAJ07983.1 - 0.098 12.4 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3960) Yippee-Mis18 PF03226.9 OAJ07984.1 - 9e-17 60.9 0.1 1.4e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 OAJ07984.1 - 0.06 13.3 0.1 1.4 8.9 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Octopine_DH PF02317.12 OAJ07984.1 - 0.096 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DNA_RNApol_7kD PF03604.8 OAJ07984.1 - 0.11 12.0 1.1 0.97 8.9 0.1 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit dCMP_cyt_deam_1 PF00383.17 OAJ07985.1 - 2.5e-24 84.8 2.1 2.6e-24 84.7 0.6 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 OAJ07985.1 - 0.0001 23.0 0.0 0.0002 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 OAJ07985.1 - 0.0021 18.3 0.0 0.0062 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 OAJ07985.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 OAJ07985.1 - 0.083 12.8 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TRAM_LAG1_CLN8 PF03798.11 OAJ07986.1 - 2.3e-32 112.1 23.4 2.3e-32 112.1 16.2 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 OAJ07986.1 - 1.4e-12 46.9 0.0 3.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein ExoD PF06055.7 OAJ07986.1 - 0.0019 17.3 0.2 0.004 16.2 0.2 1.5 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD F-box PF00646.28 OAJ07987.1 - 0.00012 21.5 0.1 0.00023 20.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 OAJ07987.1 - 0.0017 18.0 0.1 0.0045 16.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 OAJ07988.1 - 3.1e-06 26.6 0.6 5.7e-06 25.8 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 OAJ07988.1 - 0.2 11.4 0.8 0.59 9.8 0.6 1.7 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 OAJ07989.1 - 2.3e-06 27.0 0.1 4.7e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain Memo PF01875.12 OAJ07990.1 - 4.5e-70 235.6 0.0 9e-70 234.6 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein ECH PF00378.15 OAJ07991.1 - 2.6e-13 49.6 0.0 6.2e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 OAJ07991.1 - 1.2e-11 44.4 0.0 2.6e-10 40.1 0.0 2.8 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 OAJ07991.1 - 0.00092 19.2 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain F-box PF00646.28 OAJ07992.1 - 0.00012 21.6 0.6 0.00012 21.6 0.4 1.8 2 0 0 2 2 2 1 F-box domain Haem_bd PF14376.1 OAJ07992.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain F-box-like_2 PF13013.1 OAJ07992.1 - 0.035 13.8 1.8 0.2 11.3 1.3 2.4 1 1 0 1 1 1 0 F-box-like domain DUF2106 PF09879.4 OAJ07994.1 - 0.037 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) MFS_1 PF07690.11 OAJ07996.1 - 5e-30 104.4 30.3 5e-30 104.4 21.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.17 OAJ07998.1 - 3.1e-19 68.3 0.1 4.8e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 OAJ07998.1 - 1.3e-10 41.0 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 OAJ07998.1 - 5.2e-06 26.2 0.0 7.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTNNBL PF08216.6 OAJ07999.1 - 5.8e-27 93.4 0.2 5.8e-27 93.4 0.1 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 OAJ07999.1 - 0.02 15.1 3.2 0.12 12.6 0.2 3.6 4 1 0 4 4 4 0 HEAT repeats Pox_E10 PF04805.7 OAJ07999.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region Arm PF00514.18 OAJ07999.1 - 0.13 12.1 2.3 1.3 9.0 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat AT_hook PF02178.14 OAJ08000.1 - 0.0025 17.3 19.5 0.12 12.1 3.1 2.8 2 0 0 2 2 2 2 AT hook motif DUF448 PF04296.8 OAJ08000.1 - 0.016 14.8 0.0 0.071 12.7 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF448) WD40 PF00400.27 OAJ08002.1 - 5.9e-16 57.6 7.9 1.8e-06 27.5 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Neisseria_TspB PF05616.8 OAJ08003.1 - 0.008 14.6 19.8 0.013 13.9 13.7 1.2 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein Adaptin_N PF01602.15 OAJ08004.1 - 1.9e-55 188.1 0.0 1.5e-31 109.3 0.0 3.1 3 0 0 3 3 3 3 Adaptin N terminal region HEAT_2 PF13646.1 OAJ08004.1 - 1.4e-05 25.2 15.1 4e-05 23.8 3.4 5.7 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.17 OAJ08004.1 - 0.00038 20.3 4.3 1.6 8.9 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 OAJ08004.1 - 2.5 8.6 24.2 0.078 13.5 2.6 6.3 7 0 0 7 7 7 0 HEAT-like repeat SNase PF00565.12 OAJ08006.1 - 2.4e-22 79.2 1.1 3.1e-20 72.4 0.9 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue Abhydrolase_6 PF12697.2 OAJ08006.1 - 0.0023 17.8 0.9 0.0034 17.2 0.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family MOSC PF03473.12 OAJ08006.1 - 0.038 13.4 0.0 0.085 12.3 0.0 1.6 1 0 0 1 1 1 0 MOSC domain Cupin_2 PF07883.6 OAJ08007.1 - 1.1e-07 31.2 0.0 0.0072 15.8 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 OAJ08007.1 - 6.2e-06 25.7 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.7 OAJ08007.1 - 0.00037 19.8 0.0 0.00063 19.0 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_6 PF12852.2 OAJ08007.1 - 0.00081 19.0 0.2 0.0083 15.7 0.1 2.3 1 1 0 1 1 1 1 Cupin Cupin_8 PF13621.1 OAJ08007.1 - 0.0011 18.5 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.14 OAJ08007.1 - 0.013 15.1 1.7 0.038 13.6 0.4 2.1 2 1 0 2 2 2 0 AraC-like ligand binding domain Cupin_3 PF05899.7 OAJ08007.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) DUF4171 PF13775.1 OAJ08007.1 - 0.21 11.7 2.9 0.31 11.2 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) Peptidase_M1 PF01433.15 OAJ08008.1 - 1.7e-111 373.0 1.4 2.1e-70 237.8 0.2 2.3 2 0 0 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 OAJ08008.1 - 2.1e-63 214.5 0.3 3.6e-63 213.7 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 OAJ08008.1 - 1.6e-13 50.8 0.0 4.1e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily tRNA_int_end_N2 PF12928.2 OAJ08009.1 - 1.5e-12 46.7 0.0 2.9e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 OAJ08009.1 - 0.0016 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain SPX PF03105.14 OAJ08010.1 - 8.5e-28 97.9 0.1 7e-17 62.0 0.0 3.1 2 1 0 2 2 2 2 SPX domain zf-C3HC4 PF00097.20 OAJ08010.1 - 3e-07 29.9 7.5 5.2e-07 29.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 OAJ08010.1 - 5.1e-07 29.4 7.1 9.5e-07 28.5 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 OAJ08010.1 - 7.2e-07 28.7 7.9 7.2e-07 28.7 5.4 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 OAJ08010.1 - 8e-07 28.9 9.8 8e-07 28.9 6.8 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 OAJ08010.1 - 1.6e-06 27.8 11.0 3.3e-06 26.8 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 OAJ08010.1 - 7.9e-05 22.3 7.5 7.9e-05 22.3 5.2 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 OAJ08010.1 - 0.00093 18.8 5.4 0.0021 17.7 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 OAJ08010.1 - 0.0045 16.5 2.4 0.0087 15.6 1.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 OAJ08010.1 - 0.011 15.2 5.3 0.029 13.8 3.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 CagE_TrbE_VirB PF03135.9 OAJ08010.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system zf-rbx1 PF12678.2 OAJ08010.1 - 0.6 10.2 7.3 1.8 8.7 5.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger CBM_21 PF03370.8 OAJ08011.1 - 9.8e-30 102.8 0.0 1.8e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit 2Fe-2S_thioredx PF01257.14 OAJ08012.1 - 8.3e-59 197.3 0.0 1.1e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.18 OAJ08013.1 - 4e-66 222.8 0.0 8.1e-66 221.8 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.5 OAJ08013.1 - 1.4e-37 129.3 0.0 2.6e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 OAJ08013.1 - 8.8e-11 41.5 0.0 2.4e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 OAJ08013.1 - 2.1e-06 26.8 0.0 8.8e-06 24.7 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 OAJ08013.1 - 0.0065 16.3 0.0 0.095 12.5 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AMMECR1 PF01871.12 OAJ08014.1 - 3.9e-41 140.0 0.0 5.9e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 AMMECR1