# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF1302 PF06980.11 OAI95150.1 - 1.5e-64 218.7 1.2 1.7e-64 218.5 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1302) Proteasome PF00227.26 OAI95153.1 - 4.4e-16 58.9 0.0 2.8e-13 49.8 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit DUF1554 PF07588.11 OAI95158.1 - 0.03 14.1 0.2 0.03 14.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) Bac_thur_toxin PF01338.18 OAI95158.1 - 0.32 10.4 0.6 0.43 10.0 0.6 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis toxin PAS PF00989.25 OAI95161.1 - 1.5e-17 63.6 0.1 7.4e-06 25.9 0.0 3.1 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 OAI95161.1 - 2.2e-14 53.5 0.4 4.4e-09 36.5 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 OAI95161.1 - 7.2e-14 51.4 0.1 1.1e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 OAI95161.1 - 1.3e-07 31.9 2.6 0.022 15.0 0.1 3.2 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 OAI95161.1 - 3.4e-06 27.3 0.0 0.044 14.0 0.0 3.2 3 0 0 3 3 3 2 PAS domain Autotransporter PF03797.19 OAI95175.1 - 2.8e-34 118.9 7.6 5e-34 118.1 7.6 1.5 1 0 0 1 1 1 1 Autotransporter beta-domain ORMDL PF04061.14 OAI95184.1 - 8.7e-55 184.2 2.6 1e-54 184.0 2.6 1.1 1 0 0 1 1 1 1 ORMDL family DUF4551 PF15087.6 OAI95185.1 - 3.4 6.4 8.5 4.1 6.1 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rubella_E2 PF05749.11 OAI95185.1 - 4.1 6.8 9.1 5.7 6.3 9.1 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DDE_Tnp_4 PF13359.6 OAI95189.1 - 2.1e-22 79.5 0.0 2.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAI95189.1 - 3.6e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAI95189.1 - 0.0027 17.3 0.0 0.01 15.4 0.0 1.9 1 1 0 1 1 1 1 Plant transposon protein BCA_ABC_TP_C PF12399.8 OAI95189.1 - 0.031 14.2 0.3 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter DDE_Tnp_1_2 PF13586.6 OAI95189.1 - 0.051 14.0 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain CvfB_WH PF17783.1 OAI95189.1 - 0.16 11.8 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 CvfB-like winged helix domain UBM PF14377.6 OAI95191.1 - 1.1 8.8 3.3 16 5.1 0.5 2.4 2 0 0 2 2 2 0 Ubiquitin binding region Sulfatase PF00884.23 OAI95194.1 - 1.5e-28 100.1 0.0 1.6e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 OAI95194.1 - 0.068 12.7 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Prenylcys_lyase PF07156.14 OAI95196.1 - 2.1e-18 66.6 0.6 2.5e-18 66.3 0.6 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase CAP_N PF01213.19 OAI95202.1 - 3 7.3 10.5 3.3 7.1 10.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3558 PF12079.8 OAI95216.1 - 0.025 14.6 1.9 0.029 14.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) ADH_N PF08240.12 OAI95217.1 - 0.01 15.7 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Retrotran_gag_2 PF14223.6 OAI95219.1 - 1.1e-10 41.3 0.1 1.3e-10 41.1 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AMP-binding PF00501.28 OAI95229.1 - 2.2e-25 89.2 0.0 2.5e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Pheromone PF08015.11 OAI95235.1 - 0.53 11.4 6.7 2.4 9.3 0.0 3.7 3 1 0 3 3 3 0 Fungal mating-type pheromone zf-RVT PF13966.6 OAI95237.1 - 0.00011 22.8 2.5 0.00035 21.2 0.3 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase GGDEF PF00990.21 OAI95241.1 - 5.5e-27 94.5 0.1 1.2e-26 93.4 0.0 1.6 2 0 0 2 2 2 1 Diguanylate cyclase, GGDEF domain PAS_3 PF08447.12 OAI95241.1 - 1.8e-20 73.0 0.6 3.6e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAI95241.1 - 5.8e-10 39.4 2.5 1.3e-09 38.3 0.7 2.1 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 OAI95241.1 - 9.3e-09 35.3 0.1 3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAI95241.1 - 9.2e-06 25.9 0.0 2.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 OAI95241.1 - 0.00064 19.7 0.1 0.0017 18.3 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 OAI95241.1 - 0.0071 16.5 0.5 0.033 14.3 0.0 2.2 3 0 0 3 3 3 1 PAS domain Afi1 PF07792.12 OAI95257.1 - 5.3e-26 91.7 0.1 1.7e-24 86.8 0.1 2.2 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAI95257.1 - 7.8e-06 24.8 0.0 3.6e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 OAI95257.1 - 0.11 12.1 0.1 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FSA_C PF10479.9 OAI95257.1 - 5.6 5.0 5.3 7.3 4.6 5.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Phage_integrase PF00589.22 OAI95260.1 - 0.0087 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Herpes_capsid PF06112.11 OAI95269.1 - 0.12 12.5 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Calici_PP_N PF08405.11 OAI95273.1 - 0.16 10.7 0.1 23 3.7 0.0 2.7 2 1 1 3 3 3 0 Viral polyprotein N-terminal SRA1 PF07304.11 OAI95274.1 - 0.0025 17.6 0.0 0.0085 15.9 0.0 1.8 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Integrase_H2C2 PF17921.1 OAI95277.1 - 3.1e-13 49.6 0.0 4.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Apolipoprotein PF01442.18 OAI95279.1 - 0.0052 16.7 3.2 0.0066 16.3 3.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4164 PF13747.6 OAI95279.1 - 0.011 15.9 4.7 0.049 13.9 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF1043 PF06295.12 OAI95279.1 - 0.014 15.4 0.4 0.02 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Dzip-like_N PF13815.6 OAI95279.1 - 0.042 13.8 0.4 0.05 13.6 0.4 1.1 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Nfu_N PF08712.11 OAI95286.1 - 1e-32 112.0 0.0 2e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 OAI95286.1 - 3.6e-15 55.9 0.1 5.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain TFIIA PF03153.13 OAI95286.1 - 3.3 7.6 8.7 4.4 7.2 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAI95286.1 - 3.6 7.1 11.1 83 2.7 0.0 2.1 2 0 0 2 2 2 0 Spt20 family DUF3492 PF11997.8 OAI95289.1 - 1.8e-73 247.6 0.0 2.3e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) TPR_16 PF13432.6 OAI95289.1 - 0.0021 18.7 2.1 0.0051 17.4 2.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAI95289.1 - 0.0045 17.0 1.1 0.014 15.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAI95289.1 - 0.025 15.4 1.1 0.09 13.6 1.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAI95289.1 - 0.087 13.5 2.8 0.19 12.5 0.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 OAI95294.1 - 2.2e-61 207.7 0.0 3.7e-41 141.1 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAI95294.1 - 0.067 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Glyoxalase PF00903.25 OAI95294.1 - 0.14 12.3 0.0 0.27 11.5 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RT_RNaseH PF17917.1 OAI95301.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI95301.1 - 8e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF966 PF06136.13 OAI95304.1 - 0.26 10.9 5.3 0.13 11.9 3.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) COG5 PF10392.9 OAI95311.1 - 1.3e-10 41.5 1.4 2.1e-10 40.9 1.4 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 RVT_2 PF07727.14 OAI95320.1 - 7.7e-46 156.7 0.0 9.3e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAI95323.1 - 8.9e-20 70.8 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Androgen_recep PF02166.16 OAI95323.1 - 0.048 12.5 0.2 0.071 11.9 0.2 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4637 PF15470.6 OAI95328.1 - 0.042 13.6 1.9 0.067 12.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) VHP PF02209.19 OAI95330.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain Phage_integrase PF00589.22 OAI95338.1 - 3.5e-05 23.6 0.0 4.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI95338.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) UPF0183 PF03676.14 OAI95344.1 - 4.4e-18 65.8 0.0 2e-05 24.1 0.0 3.0 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) FAD_binding_2 PF00890.24 OAI95346.1 - 3.9e-14 52.6 0.0 4.2e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpb1_5 PF04998.17 OAI95354.1 - 2e-31 109.4 1.5 2.4e-31 109.2 1.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RVT_2 PF07727.14 OAI95356.1 - 1.9e-16 60.5 0.0 3.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAI95356.1 - 0.071 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) dCache_2 PF08269.11 OAI95358.1 - 3.7e-13 49.3 0.0 1.6e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 Cache domain sCache_2 PF17200.4 OAI95358.1 - 1.3e-12 47.8 0.0 9.3e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Single Cache domain 2 dCache_1 PF02743.18 OAI95358.1 - 0.091 12.5 0.0 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 Cache domain HpcH_HpaI PF03328.14 OAI95358.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family MMPL PF03176.15 OAI95364.1 - 0.0016 17.5 0.6 0.0016 17.5 0.6 2.6 2 2 0 2 2 2 1 MMPL family Phage_integrase PF00589.22 OAI95366.1 - 0.001 18.9 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family HD_3 PF13023.6 OAI95369.1 - 0.24 11.3 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 HD domain Filament PF00038.21 OAI95372.1 - 0.01 15.4 36.1 0.29 10.7 8.9 4.6 1 1 2 3 3 3 0 Intermediate filament protein FliS PF02561.14 OAI95372.1 - 0.027 14.7 0.7 0.027 14.7 0.7 3.7 3 1 1 4 4 4 0 Flagellar protein FliS GAS PF13851.6 OAI95372.1 - 0.071 12.5 37.6 0.049 13.0 10.0 4.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3882 PF07066.11 OAI95372.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Lactococcus phage M3 protein TolA_bind_tri PF16331.5 OAI95372.1 - 0.7 10.0 38.2 0.39 10.8 11.0 5.4 3 1 2 5 5 5 0 TolA binding protein trimerisation WEMBL PF05701.11 OAI95372.1 - 0.75 8.4 36.3 8.7 4.9 7.4 2.5 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.11 OAI95372.1 - 1.1 8.1 38.8 0.01 14.8 3.7 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Fez1 PF06818.15 OAI95372.1 - 1.4 9.3 34.8 4.8 7.6 15.7 3.0 1 1 1 2 2 2 0 Fez1 IF-2B PF01008.17 OAI95372.1 - 4.3 6.5 9.7 1.2 8.3 5.3 2.0 1 1 1 2 2 2 0 Initiation factor 2 subunit family DUF3818 PF12825.7 OAI95372.1 - 4.5 6.2 11.7 0.63 9.0 7.5 1.7 2 1 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF4407 PF14362.6 OAI95372.1 - 5.1 6.3 34.3 24 4.2 17.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF745 PF05335.13 OAI95372.1 - 6.2 6.5 31.5 0.19 11.4 3.3 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Retrotrans_gag PF03732.17 OAI95389.1 - 0.0074 16.5 0.2 0.012 15.9 0.2 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF5476 PF17570.2 OAI95389.1 - 0.095 13.1 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5476) DUF1952 PF09189.10 OAI95394.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) UQ_con PF00179.26 OAI95398.1 - 5.8e-38 129.7 0.0 6.9e-38 129.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HC2 PF07382.11 OAI95399.1 - 3.1e-08 33.9 38.7 0.00011 22.4 19.0 2.7 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 Fasciclin PF02469.22 OAI95404.1 - 3.2e-06 27.4 0.0 1.4e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Fasciclin domain Glyco_hydro_45 PF02015.16 OAI95408.1 - 2.4e-23 83.2 0.3 2.8e-23 83.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SPOB_ab PF14682.6 OAI95413.1 - 0.05 13.7 0.1 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal TetR_N PF00440.23 OAI95415.1 - 1.5e-09 37.5 0.1 2.8e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory proteins, tetR family TetR_C_15 PF17918.1 OAI95415.1 - 7.1e-06 26.7 2.0 7.1e-06 26.7 2.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain YgaB PF14182.6 OAI95418.1 - 0.52 10.8 7.0 0.55 10.7 3.2 2.4 2 0 0 2 2 2 0 YgaB-like protein PIN_10 PF18478.1 OAI95418.1 - 0.81 9.9 7.5 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 PIN like domain Phosphoprotein PF00922.17 OAI95419.1 - 0.25 10.9 1.4 0.33 10.5 1.4 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Herpes_pp85 PF04637.12 OAI95419.1 - 1 7.7 2.2 1.9 6.8 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Response_reg PF00072.24 OAI95426.1 - 7.7e-08 32.5 0.0 8.8e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain HD_5 PF13487.6 OAI95427.1 - 5.4e-20 71.4 0.1 1e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 HD domain HD PF01966.22 OAI95427.1 - 7.2e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 HD domain HisKA_3 PF07730.13 OAI95444.1 - 7.8e-12 45.5 7.4 7.8e-12 45.5 7.4 2.6 3 0 0 3 3 3 1 Histidine kinase HATPase_c PF02518.26 OAI95444.1 - 4.4e-07 30.4 0.1 1.7e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 OAI95444.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain ACC_epsilon PF13822.6 OAI95444.1 - 0.1 13.3 0.8 0.1 13.3 0.8 2.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit CbiD PF01888.17 OAI95444.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 CbiD Response_reg PF00072.24 OAI95445.1 - 3.3e-26 91.7 0.0 4.9e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain Trans_reg_C PF00486.28 OAI95445.1 - 1.1e-25 89.5 0.3 3.1e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 Transcriptional regulatory protein, C terminal Synapsin_N PF10581.9 OAI95445.1 - 0.027 14.4 0.2 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Synapsin N-terminal WW_FCH_linker PF16623.5 OAI95448.1 - 0.021 15.5 6.8 0.029 15.1 6.8 1.2 1 0 0 1 1 1 0 Unstructured linker region between on GAS7 protein Presenilin PF01080.17 OAI95448.1 - 0.14 10.9 1.5 0.17 10.7 1.5 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 OAI95448.1 - 0.21 11.6 9.3 0.23 11.4 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAI95448.1 - 0.49 10.0 13.4 0.65 9.6 13.4 1.1 1 0 0 1 1 1 0 Spt20 family SMAP PF15477.6 OAI95448.1 - 1.5 9.8 5.6 1.8 9.6 2.6 2.1 2 0 0 2 2 2 0 Small acidic protein family Nucleo_P87 PF07267.11 OAI95448.1 - 2.2 7.0 6.1 2.4 6.9 6.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-CCHC PF00098.23 OAI95454.1 - 0.005 16.9 5.4 0.0096 16.0 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle TTRAP PF14203.6 OAI95454.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein zf-CCHC_3 PF13917.6 OAI95454.1 - 0.016 15.1 0.6 0.039 13.9 0.6 1.7 1 0 0 1 1 1 0 Zinc knuckle Zn_ribbon_2 PF12674.7 OAI95454.1 - 0.12 13.0 0.1 0.21 12.3 0.1 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain TPR_12 PF13424.6 OAI95466.1 - 1.9e-08 34.5 14.7 0.01 16.1 0.3 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 OAI95466.1 - 6.8e-06 25.8 4.1 3.9 7.5 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 OAI95466.1 - 0.64 10.8 7.0 52 4.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat CAP_N PF01213.19 OAI95470.1 - 0.067 12.7 0.7 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MutS_IV PF05190.18 OAI95474.1 - 1e-06 29.0 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 OAI95474.1 - 0.00019 21.7 0.0 0.00022 21.5 0.0 1.1 1 0 0 1 1 1 1 MutS domain III Orthopox_F6 PF06601.12 OAI95474.1 - 0.051 13.7 0.1 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F6 protein RT_RNaseH PF17917.1 OAI95475.1 - 1.1e-12 48.2 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI95475.1 - 2.7e-07 30.5 0.0 4.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase GILT PF03227.16 OAI95484.1 - 1.5e-14 54.1 0.1 2.5e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) polyprenyl_synt PF00348.17 OAI95489.1 - 2.5e-74 249.6 0.0 3.2e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HTH_1 PF00126.27 OAI95491.1 - 3.3e-16 59.0 0.2 6.6e-16 58.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family LysR_substrate PF03466.20 OAI95491.1 - 1.2e-06 28.0 0.2 2.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 LysR substrate binding domain HTH_30 PF13556.6 OAI95491.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 PucR C-terminal helix-turn-helix domain XdhC_CoxI PF02625.16 OAI95492.1 - 1e-22 80.1 2.9 7.7e-20 70.9 0.3 2.3 2 0 0 2 2 2 2 XdhC and CoxI family MFS_1 PF07690.16 OAI95504.1 - 4.8e-22 78.4 20.5 5.6e-22 78.1 20.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAI95504.1 - 8.9e-08 31.4 11.2 2e-07 30.2 11.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4179 PF13786.6 OAI95504.1 - 0.27 11.7 1.7 0.39 11.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF971 PF06155.12 OAI95505.1 - 0.1 13.2 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF971) KAAG1 PF15354.6 OAI95505.1 - 1.5 9.4 7.8 2.6 8.7 0.6 2.7 1 1 1 2 2 2 0 Kidney-associated antigen 1 DNA_ligase_OB_2 PF14743.6 OAI95506.1 - 0.00056 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain NABP PF07990.12 OAI95506.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP TNF PF00229.18 OAI95506.1 - 0.046 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Peptidase_S8 PF00082.22 OAI95508.1 - 2.8e-25 89.2 0.5 4.2e-25 88.6 0.5 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 OAI95508.1 - 0.00015 21.8 0.1 0.00046 20.2 0.0 1.9 2 0 0 2 2 2 1 PA domain Aminotran_4 PF01063.19 OAI95517.1 - 6.6e-25 88.3 0.0 8.3e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Phasin PF05597.11 OAI95517.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ABC_trans_N PF14510.6 OAI95524.1 - 1.5e-12 48.0 0.3 2.4e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 OAI95524.1 - 7.8e-08 32.9 0.1 3.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DnaB_C PF03796.15 OAI95524.1 - 0.018 14.4 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PPL5 PF18168.1 OAI95524.1 - 0.15 11.3 0.6 0.19 11.0 0.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Inj_translocase PF16928.5 OAI95527.1 - 0.048 13.1 0.1 0.068 12.6 0.1 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome MutS_V PF00488.21 OAI95527.1 - 0.051 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 MutS domain V ATP-grasp_4 PF13535.6 OAI95533.1 - 1.4e-13 50.7 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAI95533.1 - 5.2e-07 29.5 0.0 4.8e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAI95533.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain Phage_integrase PF00589.22 OAI95535.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family WD40 PF00400.32 OAI95544.1 - 7.2e-20 71.0 6.9 5.3e-06 27.1 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 OAI95544.1 - 0.0031 16.2 1.4 0.16 10.6 0.1 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 DUF1911 PF08929.10 OAI95544.1 - 0.01 16.6 0.5 0.11 13.4 0.0 2.5 1 1 1 3 3 3 0 Domain of unknown function (DUF1911) Phlebovirus_G2 PF07245.11 OAI95544.1 - 0.037 12.5 0.0 0.05 12.1 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 W_rich_C PF07483.11 OAI95544.1 - 0.3 11.3 3.5 0.15 12.2 1.1 1.8 2 1 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain TFIIA PF03153.13 OAI95546.1 - 6.1 6.7 8.0 7.6 6.4 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RVT_2 PF07727.14 OAI95548.1 - 3e-60 203.9 0.0 3.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GntR PF00392.21 OAI95548.1 - 0.03 14.0 0.1 1.7 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Crr6 PF08847.11 OAI95548.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 1 1 2 2 2 0 Chlororespiratory reduction 6 DUF572 PF04502.13 OAI95571.1 - 0.2 11.3 8.8 0.33 10.5 8.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAGA-Tad1 PF12767.7 OAI95571.1 - 0.61 9.8 7.2 1.4 8.6 7.2 1.6 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Macoilin PF09726.9 OAI95571.1 - 0.69 8.4 6.2 0.86 8.1 6.2 1.3 1 0 0 1 1 1 0 Macoilin family DUF4718 PF15842.5 OAI95571.1 - 0.84 9.4 7.2 1.5 8.6 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) SR-25 PF10500.9 OAI95571.1 - 2.9 7.4 29.1 6.4 6.3 29.1 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 OAI95571.1 - 3 6.5 7.4 4.6 5.9 7.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 OAI95571.1 - 3.4 6.3 3.7 5 5.8 3.7 1.3 1 0 0 1 1 1 0 Presenilin FHA PF00498.26 OAI95572.1 - 0.0014 19.0 0.0 0.0023 18.2 0.0 1.3 1 0 0 1 1 1 1 FHA domain rRNA_processing PF08524.11 OAI95578.1 - 0.0053 16.8 29.0 2e+02 2.0 22.6 3.3 2 1 0 2 2 2 0 rRNA processing Retrotrans_gag PF03732.17 OAI95579.1 - 5.5e-15 55.4 0.7 8.4e-15 54.8 0.7 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAI95579.1 - 0.00015 21.7 1.9 0.00026 20.9 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAI95579.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC_6 PF15288.6 OAI95579.1 - 0.19 11.6 3.8 0.39 10.6 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle An_peroxidase PF03098.15 OAI95582.1 - 0.0005 18.8 0.0 0.00063 18.4 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase VirD1 PF07328.11 OAI95585.1 - 0.033 14.2 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 RVT_2 PF07727.14 OAI95586.1 - 1.6e-49 168.7 0.0 2.1e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAI95588.1 - 1.6e-11 44.4 0.0 2.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAI95588.1 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Septin PF00735.18 OAI95592.1 - 2.7e-08 33.5 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Septin Snf7 PF03357.21 OAI95597.1 - 6.4e-11 42.1 7.7 7.6e-11 41.9 7.7 1.0 1 0 0 1 1 1 1 Snf7 SYCE1 PF15233.6 OAI95597.1 - 0.0018 18.4 1.4 0.0026 17.8 1.4 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DMSP_lyase PF16867.5 OAI95597.1 - 0.012 15.3 0.5 0.02 14.6 0.0 1.5 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase YlqD PF11068.8 OAI95597.1 - 0.041 14.3 3.5 0.075 13.4 1.1 2.0 1 1 0 2 2 2 0 YlqD protein FKBP_C PF00254.28 OAI95597.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4148 PF13663.6 OAI95604.1 - 5.2 7.3 23.6 2 8.7 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4148) rve PF00665.26 OAI95608.1 - 1.9e-15 57.1 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAI95608.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Pheromone PF08015.11 OAI95618.1 - 7.5 7.7 8.8 1.7 9.7 1.7 3.1 3 0 0 3 3 3 0 Fungal mating-type pheromone MAGE_N PF12440.8 OAI95618.1 - 8.7 7.1 12.3 1.1 10.0 3.0 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal CAP_N PF01213.19 OAI95620.1 - 4.5 6.6 6.3 3.9 6.9 0.0 2.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DDE_Tnp_4 PF13359.6 OAI95628.1 - 1.2e-20 73.7 0.0 1.7e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAI95628.1 - 2e-05 24.3 0.2 0.00058 19.6 0.0 2.3 1 1 0 2 2 2 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 OAI95628.1 - 0.14 12.4 0.4 0.3 11.3 0.4 1.5 1 0 0 1 1 1 0 Transposase DDE domain Asn_synthase PF00733.21 OAI95641.1 - 6.3e-05 22.8 0.2 8.8e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 OAI95641.1 - 0.0063 15.7 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 OAI95641.1 - 0.095 12.2 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Ribosomal_60s PF00428.19 OAI95641.1 - 0.13 12.9 2.0 0.24 12.0 2.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Retrotrans_gag PF03732.17 OAI95644.1 - 0.057 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein ResIII PF04851.15 OAI95648.1 - 4.2e-14 52.9 0.0 6.1e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAI95648.1 - 0.019 14.7 0.0 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase ATP-synt_G PF04718.15 OAI95660.1 - 7.4e-16 58.8 2.2 9.4e-16 58.5 0.1 2.1 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF4855 PF16147.5 OAI95662.1 - 0.12 11.4 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) RNA_pol_3_Rpc31 PF11705.8 OAI95667.1 - 5.5e-25 88.9 4.6 8.5e-25 88.3 4.6 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF3824 PF12868.7 OAI95667.1 - 8.2 7.1 10.8 4 8.1 3.4 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Cation_ATPase_N PF00690.26 OAI95673.1 - 0.00029 20.5 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Frag1 PF10277.9 OAI95674.1 - 1.3e-15 57.6 4.9 1.6e-15 57.2 4.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Gaa1 PF04114.14 OAI95674.1 - 0.015 14.3 1.4 0.018 14.1 1.4 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF2079 PF09852.9 OAI95674.1 - 0.046 12.6 0.7 0.07 12.0 0.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) UPF0565 PF10561.9 OAI95677.1 - 0.014 14.7 0.4 0.014 14.7 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 GRP PF07172.11 OAI95677.1 - 8.3 7.2 24.8 0.54 11.0 0.2 3.3 2 1 0 3 3 3 0 Glycine rich protein family KOW PF00467.29 OAI95683.1 - 4.3e-05 23.3 6.9 0.1 12.6 0.6 3.5 3 0 0 3 3 3 2 KOW motif RNase_P_p30 PF01876.16 OAI95683.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit p30 Dimer_Tnp_hAT PF05699.14 OAI95685.1 - 4.7e-09 35.9 0.0 7.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region fn3_5 PF06280.12 OAI95698.1 - 1.7e-15 57.7 0.1 2.8e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Fn3-like domain NAD_binding_4 PF07993.12 OAI95706.1 - 1.3e-07 31.1 0.0 2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAI95706.1 - 5.7e-05 22.7 0.0 8.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Herpes_UL49_1 PF03117.14 OAI95713.1 - 0.18 11.1 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 UL49 family Retrotrans_gag PF03732.17 OAI95725.1 - 0.056 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein TAF4 PF05236.14 OAI95728.1 - 0.21 11.3 2.9 0.28 10.9 2.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAI95728.1 - 5.3 7.5 6.9 10 6.6 5.8 2.0 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Mt_ATP-synt_B PF05405.14 OAI95734.1 - 0.0038 16.9 0.6 0.0044 16.7 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) LEA_4 PF02987.16 OAI95734.1 - 0.065 13.3 7.0 0.11 12.6 7.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein YlqD PF11068.8 OAI95734.1 - 0.08 13.3 2.5 0.094 13.1 2.5 1.1 1 0 0 1 1 1 0 YlqD protein HsbA PF12296.8 OAI95736.1 - 1.9e-09 38.0 9.1 2.6e-09 37.5 9.1 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF3138 PF11336.8 OAI95736.1 - 0.3 9.7 8.5 0.32 9.6 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ApbA PF02558.16 OAI95741.1 - 8.9e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RdRP_2 PF00978.21 OAI95743.1 - 1.3e-13 50.7 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Serpin PF00079.20 OAI95743.1 - 0.036 13.4 0.1 0.05 12.9 0.1 1.1 1 0 0 1 1 1 0 Serpin (serine protease inhibitor) PAS_9 PF13426.7 OAI95746.1 - 5.8e-30 103.6 0.0 3.3e-22 78.7 0.0 3.1 2 1 0 2 2 2 2 PAS domain PAS_8 PF13188.7 OAI95746.1 - 1.3e-16 60.1 0.2 4.7e-09 36.1 0.1 2.5 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 OAI95746.1 - 2.8e-15 56.4 0.0 6.7e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 OAI95746.1 - 4e-15 55.8 0.2 4.2e-09 36.4 0.0 2.8 1 1 2 3 3 3 2 PAS fold PAS_4 PF08448.10 OAI95746.1 - 8.7e-14 51.7 0.2 1.5e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.24 OAI95746.1 - 0.00042 20.5 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_12 PF18095.1 OAI95746.1 - 0.0071 16.0 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 UPF0242 C-terminal PAS-like domain GGDEF PF00990.21 OAI95746.1 - 0.0087 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain MEKHLA PF08670.11 OAI95746.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 MEKHLA domain Phage_integrase PF00589.22 OAI95748.1 - 0.0018 18.1 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family CHRD PF07452.12 OAI95750.1 - 3.3e-11 44.2 0.0 4.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 CHRD domain RVT_2 PF07727.14 OAI95755.1 - 7.4e-27 94.5 0.0 8e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI95756.1 - 0.0058 16.4 1.1 0.04 13.7 1.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like Cellulase PF00150.18 OAI95758.1 - 0.14 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 OAI95760.1 - 0.0023 16.9 2.2 0.0023 16.9 2.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CAAD PF14159.6 OAI95760.1 - 0.01 15.7 1.7 0.3 10.9 0.0 2.7 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase HTH_OrfB_IS605 PF12323.8 OAI95781.1 - 8.6e-11 41.2 1.6 1.7e-10 40.2 1.6 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Thi4 PF01946.17 OAI95783.1 - 5.7e-05 22.5 0.1 7.6e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Thi4 family RVT_3 PF13456.6 OAI95787.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like Ank_3 PF13606.6 OAI95795.1 - 0.012 16.1 0.0 0.083 13.5 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 OAI95795.1 - 0.025 15.0 0.0 0.081 13.4 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 OAI95795.1 - 0.092 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RT_RNaseH PF17917.1 OAI95797.1 - 1.3e-11 44.7 0.0 3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI95797.1 - 1.8e-05 24.7 0.0 5e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Sec66 PF09802.9 OAI95800.1 - 6.9e-54 182.1 0.3 1.1e-53 181.4 0.3 1.3 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PPP4R2 PF09184.11 OAI95800.1 - 0.036 13.7 7.1 0.043 13.4 7.1 1.2 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.18 OAI95800.1 - 0.046 13.6 4.6 0.072 13.0 4.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CDC27 PF09507.10 OAI95800.1 - 0.16 11.3 12.8 0.2 11.0 12.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UvsW PF11637.8 OAI95809.1 - 5.5 7.2 6.4 2.5 8.3 1.3 2.2 1 1 1 2 2 2 0 ATP-dependant DNA helicase UvsW zf-C3HC4_3 PF13920.6 OAI95815.1 - 0.1 12.5 4.9 0.19 11.6 4.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAI95815.1 - 0.36 10.8 7.9 0.63 10.0 7.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAI95815.1 - 1.9 8.4 8.0 3.4 7.6 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MGC-24 PF05283.11 OAI95815.1 - 7.8 6.9 16.5 1.5 9.3 12.4 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pro_racemase PF05544.11 OAI95820.1 - 0.083 11.9 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Proline racemase RXT2_N PF08595.11 OAI95824.1 - 0.19 11.7 2.8 0.55 10.3 0.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2868 PF11067.8 OAI95824.1 - 0.29 10.6 2.1 0.56 9.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Cwf_Cwc_15 PF04889.12 OAI95824.1 - 5.8 6.6 10.0 3 7.5 4.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.11 OAI95824.1 - 6.3 6.8 14.1 0.27 11.2 2.6 2.5 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-CCHC PF00098.23 OAI95827.1 - 0.01 15.9 12.0 0.062 13.4 1.2 3.1 2 1 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAI95827.1 - 0.024 14.3 2.8 6.4 6.6 1.1 2.6 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 OAI95827.1 - 2.3 8.0 5.4 11 5.8 0.7 2.4 2 0 0 2 2 2 0 Zinc knuckle DSHCT PF08148.12 OAI95829.1 - 1.2e-24 86.8 0.6 3e-24 85.5 0.3 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OAI95829.1 - 6.1e-09 36.2 0.0 9.1e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain Dynamitin PF04912.14 OAI95829.1 - 0.036 13.4 0.1 0.052 12.9 0.1 1.2 1 0 0 1 1 1 0 Dynamitin BAR PF03114.18 OAI95840.1 - 1.7e-41 142.4 0.8 2.4e-41 142.0 0.8 1.1 1 0 0 1 1 1 1 BAR domain HEAT_2 PF13646.6 OAI95844.1 - 0.14 12.5 1.1 0.39 11.1 0.7 1.9 1 1 1 2 2 2 0 HEAT repeats zf-CCHC PF00098.23 OAI95844.1 - 3.1 8.0 6.1 1.4 9.1 3.7 1.7 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.14 OAI95851.1 - 3e-42 145.0 0.0 4.1e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_bind PF08675.11 OAI95851.1 - 0.0038 17.2 0.1 0.064 13.3 0.0 2.7 3 0 0 3 3 3 1 RNA binding domain DUF1820 PF08850.11 OAI95851.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Dimer_Tnp_hAT PF05699.14 OAI95858.1 - 4e-10 39.4 0.0 5.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4032 PF13224.6 OAI95858.1 - 0.061 13.2 0.1 0.073 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4032) HTH_Tnp_Tc3_2 PF01498.18 OAI95863.1 - 5.6e-11 42.5 0.0 8.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Transposase Tox-PL-2 PF15643.6 OAI95863.1 - 0.034 14.3 0.1 0.042 14.0 0.1 1.3 1 1 0 1 1 1 0 Papain fold toxin 2 Exo_endo_phos PF03372.23 OAI95864.1 - 0.009 15.6 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 OAI95867.1 - 1.9e-35 122.6 0.0 2.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ldh_1_C PF02866.18 OAI95874.1 - 1.5e-24 86.8 0.0 1.8e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain P66_CC PF16563.5 OAI95876.1 - 0.17 11.5 1.7 0.3 10.7 1.7 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 HSP70 PF00012.20 OAI95879.1 - 1.7e-13 49.6 0.2 2e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein RRM_1 PF00076.22 OAI95880.1 - 2.3e-06 27.3 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_integrase PF00589.22 OAI95883.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family AAA_31 PF13614.6 OAI95885.1 - 1.7e-29 103.0 0.0 1.8e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 OAI95885.1 - 7.6e-16 58.3 0.1 1e-15 57.9 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 OAI95885.1 - 3.1e-10 39.9 0.1 4.1e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 OAI95885.1 - 1.7e-09 37.5 1.1 2.5e-09 37.0 1.1 1.4 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 OAI95885.1 - 1.7e-09 37.3 0.2 2.2e-08 33.7 0.2 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 OAI95885.1 - 4e-07 29.5 0.2 4.2e-07 29.5 0.2 1.4 1 1 0 1 1 1 1 Anion-transporting ATPase VirC1 PF07015.11 OAI95885.1 - 1.4e-05 24.5 0.0 0.0002 20.7 0.0 2.0 2 0 0 2 2 2 1 VirC1 protein SRP54 PF00448.22 OAI95885.1 - 0.0013 18.4 0.1 0.082 12.5 0.1 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 OAI95885.1 - 0.0028 17.2 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 OAI95885.1 - 0.007 16.6 0.0 0.0083 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 OAI95885.1 - 0.0084 15.9 0.1 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 OAI95885.1 - 0.072 12.7 0.5 0.089 12.4 0.5 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAI95885.1 - 0.084 12.6 0.1 0.095 12.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 OAI95885.1 - 0.17 10.9 0.0 0.51 9.3 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Phage_AlpA PF05930.12 OAI95886.1 - 4.3e-20 71.3 0.1 5.8e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 Prophage CP4-57 regulatory protein (AlpA) LysR_substrate PF03466.20 OAI95886.1 - 2.8e-05 23.6 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_17 PF12728.7 OAI95886.1 - 0.041 14.1 0.3 0.072 13.3 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Holin_9 PF16936.5 OAI95886.1 - 0.068 13.3 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative holin DNA_topoisoIV PF00521.20 OAI95886.1 - 0.16 10.8 0.1 0.19 10.6 0.1 1.3 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Methyltransf_16 PF10294.9 OAI95893.1 - 0.003 17.3 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PDGF_N PF04692.13 OAI95893.1 - 0.0046 17.7 3.0 0.0089 16.8 3.0 1.4 1 0 0 1 1 1 1 Platelet-derived growth factor, N terminal region Androgen_recep PF02166.16 OAI95893.1 - 0.0082 15.0 4.5 0.011 14.6 4.5 1.2 1 0 0 1 1 1 1 Androgen receptor Zip PF02535.22 OAI95893.1 - 0.35 10.0 7.7 0.037 13.2 3.4 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Pex14_N PF04695.13 OAI95893.1 - 0.41 11.3 6.6 0.17 12.5 0.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.17 OAI95893.1 - 3.8 7.5 5.9 0.95 9.5 0.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-MYND PF01753.18 OAI95907.1 - 2.6e-05 24.2 19.7 5.5e-05 23.2 19.7 1.6 1 1 0 1 1 1 1 MYND finger Myb_DNA-bind_3 PF12776.7 OAI95914.1 - 0.00096 20.1 0.4 0.0019 19.1 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF4692 PF15763.5 OAI95914.1 - 0.04 14.4 0.8 0.045 14.2 0.8 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Asp_protease_2 PF13650.6 OAI95918.1 - 0.038 14.6 0.2 0.93 10.2 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease Serinc PF03348.15 OAI95925.1 - 6.6e-27 94.5 0.0 8.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) BTP PF05232.12 OAI95932.1 - 0.018 15.1 1.6 0.027 14.5 1.6 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter CRAL_TRIO PF00650.20 OAI95933.1 - 9.4e-29 100.2 0.0 1.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAI95933.1 - 3.5e-09 36.7 0.6 1.1e-08 35.1 0.4 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAI95933.1 - 1.9e-06 28.1 0.0 2.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UreE_N PF02814.15 OAI95938.1 - 0.081 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain UPF0181 PF03701.14 OAI95940.1 - 0.053 13.2 0.9 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) ATE_N PF04376.13 OAI95941.1 - 5.9e-26 90.7 0.2 1.1e-25 89.8 0.2 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus ATE_C PF04377.15 OAI95941.1 - 6.5e-08 33.3 0.1 1e-07 32.7 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus PQ-loop PF04193.14 OAI95943.1 - 7.9e-11 41.6 0.2 1.1e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 PQ loop repeat DUF4537 PF15057.6 OAI95946.1 - 0.0039 17.2 0.1 0.024 14.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Imm52 PF15579.6 OAI95949.1 - 4.9e-06 26.3 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Immunity protein 52 Spt5-NGN PF03439.13 OAI95950.1 - 1.1e-18 66.9 0.0 2.9e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 OAI95950.1 - 6.8e-16 59.1 2.7 6.8e-16 59.1 2.7 3.5 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal ADH_N_assoc PF13823.6 OAI95950.1 - 0.00039 20.3 0.1 0.0013 18.6 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DUF2457 PF10446.9 OAI95950.1 - 1 8.4 23.4 1.7 7.7 23.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 OAI95950.1 - 1.7 8.0 18.3 2.8 7.3 18.3 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAI95950.1 - 2.6 7.3 15.7 4.3 6.6 15.7 1.3 1 0 0 1 1 1 0 BUD22 Cyt-b5 PF00173.28 OAI95954.1 - 2.4e-20 72.4 0.1 3e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Leuk-A4-hydro_C PF09127.11 OAI95957.1 - 1.7e-37 127.9 0.0 2.5e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.20 OAI95957.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Importin_rep_2 PF18786.1 OAI95959.1 - 0.006 16.4 0.1 0.006 16.4 0.1 1.7 2 0 0 2 2 2 1 Importin 13 repeat TAF4 PF05236.14 OAI95969.1 - 0.12 12.1 1.7 0.3 10.8 1.7 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAI95969.1 - 4.3 7.8 7.7 8.4 6.9 6.9 1.9 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP FAM199X PF15814.5 OAI95974.1 - 0.52 9.3 6.2 0.54 9.3 6.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X UQ_con PF00179.26 OAI95977.1 - 2.2e-41 140.8 0.0 2.9e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAI95977.1 - 0.011 16.1 0.5 0.017 15.4 0.5 1.4 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 OAI95977.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 OAI95977.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Fip1 PF05182.13 OAI95977.1 - 0.19 11.3 0.2 0.38 10.3 0.2 1.5 1 0 0 1 1 1 0 Fip1 motif Myc_N PF01056.18 OAI95996.1 - 0.017 15.0 1.3 0.017 15.0 1.3 1.7 2 0 0 2 2 2 0 Myc amino-terminal region ORC6 PF05460.13 OAI95996.1 - 0.84 8.8 3.3 1.4 8.1 3.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Nop14 PF04147.12 OAI95999.1 - 0.15 10.3 4.1 0.18 9.9 4.1 1.1 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_3 PF07859.13 OAI96000.1 - 8.8e-06 25.7 0.0 8.9e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAI96000.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase CDC45 PF02724.14 OAI96004.1 - 0.1 10.9 8.2 0.14 10.4 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein BBP1_N PF15271.6 OAI96004.1 - 0.62 10.8 9.7 0.22 12.3 2.6 2.4 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein Transthyretin PF00576.21 OAI96006.1 - 2.6e-33 115.0 0.0 1.3e-32 112.7 0.0 1.8 1 1 0 1 1 1 1 HIUase/Transthyretin family Clathrin_H_link PF13838.6 OAI96011.1 - 1.8e-30 104.6 0.1 2.8e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 Clathrin-H-link Pes-10 PF07149.11 OAI96011.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Pes-10 CTC1_2 PF15491.6 OAI96012.1 - 0.034 13.4 0.1 0.04 13.2 0.1 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Hid1 PF12722.7 OAI96018.1 - 1.3e-28 99.7 1.3 1.3e-28 99.6 0.7 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAI96018.1 - 7.4e-10 37.9 0.0 8.2e-10 37.7 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein MAP65_ASE1 PF03999.12 OAI96023.1 - 0.76 8.4 5.7 1.7 7.3 5.7 1.6 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Glyoxalase PF00903.25 OAI96025.1 - 0.021 15.0 0.0 0.26 11.5 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AcylCoA_DH_N PF12418.8 OAI96025.1 - 0.036 14.1 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Vault_4 PF17796.1 OAI96030.1 - 7.1 6.8 5.9 17 5.6 0.8 2.6 2 1 0 2 2 2 0 Major Vault Protein repeat domain HeH PF12949.7 OAI96036.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Glyco_hydro_45 PF02015.16 OAI96038.1 - 6.6e-19 68.7 2.2 8.2e-19 68.4 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Tim54 PF11711.8 OAI96041.1 - 0.005 15.7 3.0 0.0066 15.3 3.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DnaJ PF00226.31 OAI96041.1 - 0.011 15.8 1.5 0.024 14.7 0.0 2.3 3 1 0 3 3 3 0 DnaJ domain Presenilin PF01080.17 OAI96041.1 - 0.017 13.9 3.1 0.021 13.6 3.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 OAI96041.1 - 0.15 10.8 0.6 0.18 10.5 0.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PDDEXK_9 PF08011.11 OAI96041.1 - 2.1 8.3 7.3 7.5 6.5 7.6 1.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily NPR3 PF03666.13 OAI96041.1 - 4.8 5.9 9.8 6.2 5.5 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5427 PF10310.9 OAI96041.1 - 6.5 5.6 12.8 8.4 5.2 12.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Neur_chan_memb PF02932.16 OAI96041.1 - 6.8 6.7 6.1 9.7 6.2 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 OAI96041.1 - 7.4 4.7 10.8 8.8 4.5 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OAI96041.1 - 8.7 6.1 12.2 11 5.8 12.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phage_integrase PF00589.22 OAI96045.1 - 0.00021 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Acetate_kinase PF00871.17 OAI96046.1 - 2.7e-20 72.4 0.0 3e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF4890 PF16231.5 OAI96049.1 - 0.034 14.6 0.3 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) ImcF-related_N PF14331.6 OAI96051.1 - 5.5e-42 143.9 1.3 9.8e-42 143.1 1.3 1.3 1 0 0 1 1 1 1 ImcF-related N-terminal domain ORC6 PF05460.13 OAI96055.1 - 0.017 14.4 2.7 0.024 13.9 2.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RPN2_C PF18004.1 OAI96055.1 - 0.078 12.9 0.6 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CbtA PF09490.10 OAI96055.1 - 0.13 12.0 0.3 0.37 10.5 0.5 1.7 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) PPP4R2 PF09184.11 OAI96055.1 - 0.55 9.8 7.5 0.83 9.2 7.5 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 OAI96055.1 - 1.4 7.6 2.3 1.9 7.1 2.3 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 OAI96055.1 - 5.5 6.6 12.3 30 4.2 0.3 3.1 3 0 0 3 3 3 0 FAM176 family Nop14 PF04147.12 OAI96055.1 - 6.3 4.9 15.5 8.9 4.4 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 OAI96055.1 - 6.7 7.2 23.3 5.9 7.4 19.0 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Collagen PF01391.18 OAI96061.1 - 5e-26 90.2 133.4 6.3e-11 41.9 35.8 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Het-C PF07217.11 OAI96066.1 - 0.21 10.1 0.5 0.21 10.1 0.5 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HeH PF12949.7 OAI96073.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain Alpha-E PF04168.12 OAI96082.1 - 0.048 13.5 0.4 0.08 12.7 0.4 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. TFIIA PF03153.13 OAI96094.1 - 0.0074 16.3 9.8 0.0094 16.0 9.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pro-rich_19 PF15455.6 OAI96094.1 - 0.035 13.2 4.3 0.065 12.4 4.3 1.3 1 0 0 1 1 1 0 Proline-rich 19 DUF2722 PF10846.8 OAI96094.1 - 0.18 10.7 12.9 0.25 10.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GAPT PF11770.8 OAI96094.1 - 0.4 10.5 0.1 0.4 10.5 0.1 1.5 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Spt20 PF12090.8 OAI96094.1 - 1.9 8.0 21.3 2.9 7.4 21.3 1.2 1 0 0 1 1 1 0 Spt20 family MCM PF00493.23 OAI96095.1 - 4.5e-35 120.8 0.1 5.5e-35 120.5 0.1 1.1 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 OAI96095.1 - 0.074 12.4 0.1 0.22 10.9 0.1 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTP_transf_9 PF04248.12 OAI96098.1 - 7.5e-13 48.2 0.1 1.1e-12 47.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Methyltransf_16 PF10294.9 OAI96103.1 - 7.2e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 OAI96103.1 - 0.00025 20.5 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAI96103.1 - 0.0025 18.5 0.1 0.0086 16.8 0.1 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAI96103.1 - 0.052 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAI96103.1 - 0.069 13.8 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAI96103.1 - 0.12 12.2 0.0 2.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAI96103.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Lipoprotein_2 PF00921.17 OAI96107.1 - 0.057 13.0 3.6 0.078 12.5 3.6 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein HemY_N PF07219.13 OAI96107.1 - 0.81 9.9 8.6 2.2 8.5 8.6 1.7 1 0 0 1 1 1 0 HemY protein N-terminus Peptidase_M1 PF01433.20 OAI96111.1 - 3.8e-24 85.5 0.1 5.5e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAI96111.1 - 6.3e-23 81.9 0.0 8.7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3439 PF11921.8 OAI96111.1 - 0.75 9.8 4.7 1.6 8.7 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) rve PF00665.26 OAI96115.1 - 4.1e-17 62.5 0.1 7.9e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI96115.1 - 0.00018 21.6 0.3 0.00049 20.1 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAI96115.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WD40 PF00400.32 OAI96119.1 - 9.8e-14 51.5 5.8 0.00016 22.4 0.0 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 OAI96119.1 - 1.1e-06 27.6 0.4 0.00049 18.9 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 EzrA PF06160.12 OAI96119.1 - 0.26 9.4 1.2 0.35 9.0 1.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Cecropin PF00272.19 OAI96124.1 - 0.021 14.5 0.1 0.063 13.0 0.1 1.8 1 0 0 1 1 1 0 Cecropin family LPD5 PF18799.1 OAI96124.1 - 0.035 14.5 0.6 0.035 14.5 0.6 3.2 2 2 1 3 3 3 0 Large polyvalent protein-associated domain 5 NPIP PF06409.11 OAI96124.1 - 0.07 12.2 1.2 0.16 11.0 1.0 1.7 1 1 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) YiiD_C PF09500.10 OAI96124.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.0 2 1 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) DUF948 PF06103.11 OAI96124.1 - 0.29 11.4 17.8 2.2 8.6 0.9 4.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PMEI PF04043.15 OAI96124.1 - 0.36 11.2 6.8 6.3 7.1 1.7 2.6 2 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF720 PF05302.11 OAI96124.1 - 0.62 9.9 10.0 0.038 13.8 2.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF720) Fib_alpha PF08702.10 OAI96124.1 - 0.67 10.1 25.3 1 9.5 0.5 3.7 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF2431 PF10354.9 OAI96124.1 - 0.96 9.7 2.8 1.6 9.0 0.5 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF2431) DUF4041 PF13250.6 OAI96124.1 - 1.1 9.2 7.2 6.9 6.6 0.2 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4041) DUF4795 PF16043.5 OAI96124.1 - 1.4 8.5 30.9 0.14 11.7 9.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF648 PF04890.13 OAI96124.1 - 1.5 8.5 6.7 0.36 10.5 2.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF648) NPV_P10 PF05531.12 OAI96124.1 - 1.5 9.3 14.0 3.7 8.1 1.3 4.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein ZapD PF07072.11 OAI96124.1 - 2.3 7.9 17.4 0.052 13.3 2.5 3.5 2 2 0 2 2 2 0 Cell division protein DciA PF05258.12 OAI96124.1 - 2.7 8.4 6.1 27 5.2 0.0 3.7 4 0 0 4 4 4 0 Dna[CI] antecedent, DciA Rab5-bind PF09311.11 OAI96124.1 - 4.4 6.6 35.9 0.31 10.4 12.1 3.9 2 2 2 4 4 4 0 Rabaptin-like protein DUF4407 PF14362.6 OAI96124.1 - 4.4 6.6 28.9 0.045 13.1 9.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 OAI96124.1 - 4.7 6.0 39.4 0.12 11.3 11.6 2.9 2 1 0 2 2 2 0 Spc7 kinetochore protein SPG4 PF17325.2 OAI96124.1 - 7.1 7.8 12.6 0.22 12.6 3.1 2.6 2 1 0 2 2 2 0 Stationary phase protein 4 Bacillus_HBL PF05791.11 OAI96124.1 - 7.6 6.3 12.1 0.97 9.2 0.2 3.4 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Septin PF00735.18 OAI96133.1 - 2.3e-110 368.3 0.2 2.8e-110 368.0 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAI96133.1 - 3.9e-09 36.6 0.0 1.5e-08 34.7 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAI96133.1 - 4.1e-05 23.5 0.1 0.00035 20.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OAI96133.1 - 0.00024 20.5 1.0 0.00045 19.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 OAI96133.1 - 0.00024 20.7 0.7 0.011 15.3 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAI96133.1 - 0.004 17.2 2.8 0.95 9.5 0.1 2.7 2 1 1 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 OAI96133.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 OAI96133.1 - 0.02 14.4 0.0 0.41 10.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Microtub_bd PF16796.5 OAI96133.1 - 0.024 14.6 0.2 0.39 10.6 0.0 2.6 2 1 0 3 3 3 0 Microtubule binding ABC_tran PF00005.27 OAI96133.1 - 0.032 14.7 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 OAI96133.1 - 0.04 14.2 0.1 0.096 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAI96133.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 OAI96133.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 OAI96133.1 - 0.18 12.2 0.9 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_M16 PF00675.20 OAI96140.1 - 3.3e-22 79.1 0.0 4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) TAL_FSA PF00923.19 OAI96140.1 - 0.0095 15.3 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Nudix_N PF12535.8 OAI96140.1 - 0.094 12.3 0.5 0.32 10.6 0.1 1.9 2 0 0 2 2 2 0 Hydrolase of X-linked nucleoside diphosphate N terminal HlyD_3 PF13437.6 OAI96141.1 - 3.3e-14 53.5 0.0 1.6e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 HlyD family secretion protein HlyD PF00529.20 OAI96141.1 - 5.5e-06 26.2 0.0 7e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 HlyD membrane-fusion protein of T1SS Biotin_lipoyl_2 PF13533.6 OAI96141.1 - 3.7e-05 23.5 0.2 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 OAI96141.1 - 5.8e-05 22.4 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M23 PF01551.22 OAI96141.1 - 0.15 12.2 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M23 LRR_4 PF12799.7 OAI96145.1 - 5.5e-07 29.8 8.2 0.16 12.5 1.2 5.8 5 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAI96145.1 - 0.00056 20.1 6.3 3.5 8.6 0.0 6.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 OAI96145.1 - 0.00061 19.5 10.5 0.047 13.5 0.2 6.0 5 2 1 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 OAI96145.1 - 0.0037 17.2 15.2 1.6 9.0 0.4 6.4 8 0 0 8 8 8 2 Leucine Rich repeat BUD22 PF09073.10 OAI96145.1 - 0.16 11.2 20.3 0.23 10.8 20.3 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OAI96145.1 - 7.1 4.8 12.0 12 4.1 12.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DDE_3 PF13358.6 OAI96148.1 - 1.2e-10 41.3 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OAI96148.1 - 2.3e-10 40.5 0.1 3.6e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Transposase Transthyretin PF00576.21 OAI96150.1 - 1.8e-36 125.2 0.0 2.1e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family bMG3 PF11974.8 OAI96150.1 - 0.00013 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 OAI96150.1 - 0.0096 15.9 1.3 0.15 12.1 0.3 2.7 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 OAI96150.1 - 0.086 13.1 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF824 PF05688.11 OAI96150.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Hydrolase_like PF13242.6 OAI96152.1 - 3.7e-10 39.7 0.1 4.2e-10 39.6 0.1 1.0 1 0 0 1 1 1 1 HAD-hyrolase-like CFEM PF05730.11 OAI96153.1 - 1.1e-08 35.1 11.3 1.9e-08 34.3 11.3 1.4 1 0 0 1 1 1 1 CFEM domain HSP70 PF00012.20 OAI96155.1 - 4.7e-07 28.4 0.2 5.7e-07 28.1 0.2 1.1 1 0 0 1 1 1 1 Hsp70 protein Nipped-B_C PF12830.7 OAI96158.1 - 1.5e-25 90.2 0.2 1.9e-25 89.9 0.2 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus Asp_protease_2 PF13650.6 OAI96161.1 - 0.0013 19.4 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAI96161.1 - 0.085 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAI96163.1 - 0.67 10.1 3.7 1.4 9.1 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 OAI96170.1 - 6e-26 91.3 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAI96170.1 - 1.4e-16 60.3 0.0 2.5e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAI96170.1 - 1.7e-14 53.7 0.0 3.6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI96170.1 - 0.00024 21.3 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAI96170.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger UDPG_MGDP_dh PF00984.19 OAI96173.1 - 4e-24 84.6 0.0 7.9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 OAI96173.1 - 4e-22 78.6 0.0 1e-21 77.3 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 OAI96173.1 - 1.9e-11 43.9 0.0 4.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_11 PF14833.6 OAI96173.1 - 0.13 12.5 0.7 0.26 11.5 0.7 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF1912 PF08930.10 OAI96174.1 - 0.077 13.2 0.2 0.43 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) SLATT_fungal PF18142.1 OAI96174.1 - 0.093 12.7 0.2 10 6.2 0.0 3.1 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Rx_N PF18052.1 OAI96174.1 - 0.2 12.0 2.0 16 5.8 0.2 2.7 2 1 0 2 2 2 0 Rx N-terminal domain Carn_acyltransf PF00755.20 OAI96186.1 - 5.3e-67 226.8 0.0 6.5e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Nop14 PF04147.12 OAI96191.1 - 0.0059 14.9 13.6 0.0063 14.8 13.6 1.1 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.18 OAI96191.1 - 0.05 13.5 5.3 0.07 13.0 5.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 OAI96191.1 - 0.059 12.7 15.2 0.087 12.1 15.2 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAI96191.1 - 0.067 12.9 13.2 0.11 12.2 13.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 OAI96191.1 - 0.28 10.3 13.9 0.45 9.6 13.9 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 OAI96191.1 - 0.37 9.0 12.2 0.45 8.8 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 OAI96191.1 - 0.37 10.4 9.2 0.49 10.1 9.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FAM176 PF14851.6 OAI96191.1 - 0.42 10.3 8.9 0.94 9.1 8.9 1.7 1 0 0 1 1 1 0 FAM176 family YL1 PF05764.13 OAI96191.1 - 0.53 10.4 23.9 0.091 12.9 20.1 1.5 1 1 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 OAI96191.1 - 0.82 7.7 21.5 1.2 7.2 21.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 OAI96191.1 - 3 7.2 13.9 4.2 6.7 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Prothymosin PF03247.14 OAI96191.1 - 3.7 8.1 27.7 0.5 10.8 22.6 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family PPP4R2 PF09184.11 OAI96191.1 - 7 6.1 17.9 0.71 9.4 13.5 1.6 2 0 0 2 2 2 0 PPP4R2 Lin-8 PF03353.15 OAI96191.1 - 9.2 5.7 10.2 5.7 6.4 8.7 1.4 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist CobT PF06213.12 OAI96191.1 - 9.2 5.6 16.7 15 4.8 16.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DHHC PF01529.20 OAI96199.1 - 1e-33 116.3 3.3 1e-33 116.3 3.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase RCR PF12273.8 OAI96199.1 - 0.099 13.3 3.3 0.14 12.9 0.1 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Arc_PepC_II PF06847.11 OAI96199.1 - 0.47 11.0 2.5 1.1 9.8 2.5 1.6 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Esterase PF00756.20 OAI96218.1 - 6.2e-36 124.3 0.0 8.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 OAI96218.1 - 0.069 12.0 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme MAT1 PF06391.13 OAI96220.1 - 0.29 10.9 4.0 0.45 10.3 4.0 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DEAD PF00270.29 OAI96229.1 - 1.6e-15 57.3 0.0 2.9e-15 56.5 0.0 1.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAI96229.1 - 7.4e-06 26.3 0.0 3.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAI96229.1 - 0.005 16.8 0.0 0.0069 16.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit OrsD PF12013.8 OAI96233.1 - 0.00041 20.8 0.0 0.0015 19.0 0.0 2.0 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Retrotran_gag_2 PF14223.6 OAI96249.1 - 2.4e-16 59.6 0.2 3.6e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAI96249.1 - 0.00036 20.3 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAI96249.1 - 0.29 11.3 2.3 0.85 9.8 2.3 1.8 1 0 0 1 1 1 0 Zinc knuckle FHA PF00498.26 OAI96261.1 - 0.016 15.6 0.0 0.024 15.0 0.0 1.3 1 0 0 1 1 1 0 FHA domain Xpo1 PF08389.12 OAI96263.1 - 0.034 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Exportin 1-like protein NAD_binding_5 PF07994.12 OAI96265.1 - 2.9e-25 89.3 0.0 3.4e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Yae1_N PF09811.9 OAI96271.1 - 6.7e-05 22.5 10.5 6.7e-05 22.5 10.5 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Resolvase PF00239.21 OAI96287.1 - 2.2e-21 76.5 0.1 2.4e-21 76.4 0.1 1.0 1 0 0 1 1 1 1 Resolvase, N terminal domain LcrR PF09621.10 OAI96287.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.5 1 1 1 2 2 2 0 Type III secretion system regulator (LcrR) FYVE PF01363.21 OAI96291.1 - 4.7e-19 68.3 9.7 4.7e-19 68.3 9.7 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 OAI96291.1 - 7.9e-09 35.7 3.3 7.9e-09 35.7 3.3 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 OAI96291.1 - 3.8e-05 23.3 4.6 3.8e-05 23.3 4.6 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAI96291.1 - 8.3e-05 22.4 2.7 8.3e-05 22.4 2.7 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAI96291.1 - 0.003 17.6 3.3 0.003 17.6 3.3 3.2 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAI96291.1 - 0.01 15.7 1.9 0.01 15.7 1.9 3.9 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAI96291.1 - 0.012 15.9 4.7 0.012 15.9 4.7 3.1 3 1 0 3 3 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 OAI96291.1 - 0.025 14.2 3.6 0.025 14.2 3.6 3.2 3 1 0 3 3 2 0 Zinc-ribbon, C4HC2 type HypA PF01155.19 OAI96291.1 - 0.06 13.4 4.1 1.2 9.2 2.6 2.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MR_MLE_C PF13378.6 OAI96291.1 - 0.098 12.2 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like PaaX_C PF08223.11 OAI96291.1 - 0.11 12.8 0.0 7.1 7.0 0.0 2.2 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain FYVE_2 PF02318.16 OAI96291.1 - 0.54 10.5 13.6 0.17 12.1 6.4 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger NAD_binding_4 PF07993.12 OAI96295.1 - 2.8e-05 23.4 0.0 0.00021 20.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 OAI96295.1 - 0.022 14.6 0.2 0.056 13.4 0.0 1.7 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 OAI96295.1 - 0.034 13.3 0.0 0.052 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FrhB_FdhB_N PF04422.13 OAI96295.1 - 0.047 13.8 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Epimerase PF01370.21 OAI96295.1 - 0.1 12.1 0.1 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAI96295.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 OAI96295.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Ras PF00071.22 OAI96303.1 - 3.7e-65 218.5 0.0 4.3e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAI96303.1 - 6.4e-34 116.7 0.1 9.7e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAI96303.1 - 2.4e-13 49.9 0.0 2.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAI96303.1 - 7.5e-05 22.3 0.0 0.00019 21.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAI96303.1 - 0.00022 20.7 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAI96303.1 - 0.00028 21.0 0.0 0.00051 20.1 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAI96303.1 - 0.00036 20.5 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 OAI96303.1 - 0.035 13.6 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAI96303.1 - 0.038 14.4 0.0 0.057 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 OAI96303.1 - 0.053 12.6 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 OAI96303.1 - 0.053 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 OAI96303.1 - 0.058 12.9 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.12 OAI96303.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 OAI96303.1 - 0.081 13.3 0.1 0.95 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAI96303.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 OAI96303.1 - 0.21 11.1 0.0 0.49 9.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MULE PF10551.9 OAI96315.1 - 8.8e-13 48.5 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAI96315.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family PHP PF02811.19 OAI96322.1 - 9.2e-10 39.1 0.2 1.8e-09 38.1 0.2 1.5 1 1 0 1 1 1 1 PHP domain Sel1 PF08238.12 OAI96325.1 - 0.0016 19.1 15.0 0.048 14.4 0.1 5.2 6 0 0 6 6 6 2 Sel1 repeat DUF2587 PF10759.9 OAI96325.1 - 0.031 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TPR_2 PF07719.17 OAI96325.1 - 0.049 13.8 0.0 0.55 10.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MULE PF10551.9 OAI96340.1 - 1e-25 89.9 0.2 2.9e-25 88.5 0.2 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAI96340.1 - 6.6e-06 26.7 0.3 1.3e-05 25.8 0.3 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF5071 PF16804.5 OAI96340.1 - 0.11 12.8 1.1 2 8.7 0.1 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF5071) STAT_int PF02865.17 OAI96340.1 - 0.12 12.8 1.5 0.4 11.1 0.4 2.2 2 0 0 2 2 2 0 STAT protein, protein interaction domain RT_RNaseH PF17917.1 OAI96341.1 - 1.1e-11 44.9 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI96341.1 - 7.2e-08 32.4 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF908 PF06012.12 OAI96343.1 - 6.6 6.0 10.7 0.11 11.9 3.5 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) CoA_transf_3 PF02515.17 OAI96349.1 - 0.022 13.9 0.4 0.031 13.4 0.4 1.2 1 0 0 1 1 1 0 CoA-transferase family III Rib_recp_KP_reg PF05104.12 OAI96350.1 - 0.2 12.7 6.9 0.23 12.5 6.9 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Neisseria_TspB PF05616.13 OAI96350.1 - 0.99 7.8 5.5 0.92 7.9 5.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein RVT_3 PF13456.6 OAI96353.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like MdcG PF10620.9 OAI96354.1 - 0.067 13.0 0.8 0.076 12.8 0.8 1.1 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG ICMT PF04140.14 OAI96365.1 - 1.3e-15 57.6 0.6 3.6e-15 56.2 0.6 1.7 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAI96365.1 - 1.6e-09 38.1 3.1 1.2e-08 35.3 3.1 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase Glyco_hydro_45 PF02015.16 OAI96375.1 - 1e-07 32.1 0.1 1.1e-07 32.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 DUF1206 PF06724.11 OAI96381.1 - 0.052 13.6 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) MULE PF10551.9 OAI96384.1 - 1.3e-10 41.5 0.1 4.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAI96384.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Transposase, Mutator family Herpes_ORF11 PF04797.13 OAI96386.1 - 0.00026 19.9 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Asp_protease_2 PF13650.6 OAI96386.1 - 0.012 16.2 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 OAI96386.1 - 0.11 13.0 0.0 0.63 10.6 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease FadA PF09403.10 OAI96389.1 - 0.053 14.0 1.4 0.14 12.6 1.4 1.7 1 0 0 1 1 1 0 Adhesion protein FadA Mur_ligase_C PF02875.21 OAI96393.1 - 0.16 12.2 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Asp PF00026.23 OAI96394.1 - 9.8e-14 51.5 0.0 1.2e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Retrotrans_gag PF03732.17 OAI96397.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Retrotrans_gag PF03732.17 OAI96403.1 - 0.011 16.0 0.2 0.022 15.0 0.2 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein PPP4R2 PF09184.11 OAI96408.1 - 0.04 13.5 8.3 0.053 13.1 8.3 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAI96408.1 - 1.9 6.6 8.6 1.9 6.6 8.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAI96408.1 - 2.1 7.6 11.1 3.4 6.9 11.1 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 OAI96408.1 - 4.6 5.7 7.8 5.8 5.3 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 OAI96419.1 - 4.9e-06 26.2 22.0 5.1e-06 26.2 22.0 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OAI96419.1 - 2.6e-05 22.8 12.2 2.6e-05 22.8 12.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.9 OAI96419.1 - 0.044 12.6 3.7 0.047 12.5 3.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 OAI96419.1 - 0.074 12.3 6.5 0.085 12.1 6.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 OAI96419.1 - 0.12 11.1 16.1 0.13 11.0 16.1 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 OAI96419.1 - 0.14 12.4 34.4 0.23 11.7 34.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 OAI96419.1 - 0.84 7.8 37.9 1.1 7.4 37.9 1.1 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.11 OAI96419.1 - 0.96 8.1 14.5 1.1 7.9 14.5 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SpoIIIAH PF12685.7 OAI96419.1 - 1.3 8.9 18.2 2 8.2 18.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein SLC12 PF03522.15 OAI96419.1 - 1.7 7.5 10.6 2 7.4 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 OAI96419.1 - 1.8 7.2 12.3 2.2 6.9 12.3 1.1 1 0 0 1 1 1 0 Raftlin Plasmodium_Vir PF05795.11 OAI96419.1 - 1.9 7.8 9.1 2.3 7.6 9.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 OAI96419.1 - 2.8 7.9 7.1 3.6 7.5 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.11 OAI96419.1 - 3 6.2 7.3 3.3 6.1 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2151 PF10221.9 OAI96419.1 - 4.9 5.6 9.9 5.9 5.4 9.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4045 PF13254.6 OAI96419.1 - 5.2 6.6 13.7 6.8 6.2 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PPL5 PF18168.1 OAI96419.1 - 5.7 6.1 10.5 7.1 5.8 10.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Mpp10 PF04006.12 OAI96419.1 - 6.9 5.0 40.0 8.8 4.6 40.0 1.1 1 0 0 1 1 1 0 Mpp10 protein AAA PF00004.29 OAI96424.1 - 7.1e-33 113.8 0.0 1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAI96424.1 - 1.2e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAI96424.1 - 1.2e-05 25.7 0.1 6.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAI96424.1 - 1.8e-05 24.8 0.2 0.00043 20.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAI96424.1 - 0.0013 19.0 0.1 0.15 12.3 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAI96424.1 - 0.0023 18.1 0.0 0.016 15.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 OAI96424.1 - 0.01 15.4 0.3 0.069 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 OAI96424.1 - 0.011 15.8 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAI96424.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAI96424.1 - 0.032 13.6 0.1 0.29 10.5 0.0 2.3 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAI96424.1 - 0.055 13.6 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAI96424.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAI96424.1 - 0.1 12.9 0.2 1.3 9.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 OAI96424.1 - 0.11 12.1 0.3 0.68 9.6 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAI96424.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zot PF05707.12 OAI96424.1 - 0.15 11.7 0.1 2 8.0 0.0 2.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) ATPase PF06745.13 OAI96424.1 - 0.16 11.3 0.1 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 OAI96424.1 - 0.19 11.6 0.5 14 5.5 0.0 2.4 1 1 1 2 2 2 0 NTPase S100PBPR PF15427.6 OAI96427.1 - 0.006 15.9 0.1 0.0077 15.5 0.1 1.1 1 0 0 1 1 1 1 S100P-binding protein DUF2201_N PF13203.6 OAI96427.1 - 0.46 10.0 4.6 0.64 9.6 4.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.14 OAI96427.1 - 1.2 7.4 4.6 1.3 7.3 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Asn_synthase PF00733.21 OAI96436.1 - 5.8e-19 69.0 0.1 7.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_6 PF13522.6 OAI96436.1 - 0.017 15.3 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 OAI96436.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 OAI96436.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC rve PF00665.26 OAI96448.1 - 3e-17 62.9 0.0 5.7e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OAI96448.1 - 0.0032 17.7 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 DDE domain MLVIN_C PF18697.1 OAI96448.1 - 0.015 15.4 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Phage_integrase PF00589.22 OAI96458.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Lipocalin_5 PF13924.6 OAI96458.1 - 0.0088 15.8 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Lipocalin-like domain IFT43 PF15305.6 OAI96464.1 - 0.34 11.1 7.0 0.079 13.1 3.3 1.8 2 0 0 2 2 2 0 Intraflagellar transport protein 43 TetR PF13972.6 OAI96475.1 - 2.3e-15 56.5 0.0 2.6e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Bacterial transcriptional repressor GhoS PF11080.8 OAI96475.1 - 0.038 14.0 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Endoribonuclease GhoS OEP PF02321.18 OAI96476.1 - 6.4e-49 166.3 42.4 8.7e-29 100.7 13.9 2.1 2 0 0 2 2 2 2 Outer membrane efflux protein SMC_N PF02463.19 OAI96476.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF630 PF04783.12 OAI96476.1 - 2.8 8.2 6.2 1.4 9.2 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF630) RNA_pol_Rpb4 PF03874.16 OAI96479.1 - 4.9e-14 52.7 0.0 1.6e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 Rad60-SLD PF11976.8 OAI96485.1 - 0.00039 20.2 0.1 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Keratin_2_head PF16208.5 OAI96488.1 - 0.0022 18.1 7.2 0.0022 18.1 7.2 1.8 2 0 0 2 2 2 1 Keratin type II head GET2 PF08690.10 OAI96488.1 - 0.18 11.5 5.3 0.31 10.7 5.3 1.4 1 1 0 1 1 1 0 GET complex subunit GET2 VIR_N PF15912.5 OAI96488.1 - 9 5.8 13.1 0.3 10.6 2.4 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal Vmethyltransf PF01660.17 OAI96498.1 - 4.6e-32 111.2 0.0 5.9e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Viral methyltransferase Fungal_trans PF04082.18 OAI96500.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.6 OAI96500.1 - 0.64 10.0 5.9 8.5 6.4 0.4 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 OAI96500.1 - 2.2 6.3 8.3 0.039 12.1 1.3 1.5 2 0 0 2 2 2 0 Sporozoite P67 surface antigen FAD_binding_2 PF00890.24 OAI96509.1 - 5.4e-17 62.0 0.1 7.7e-17 61.5 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Gag_spuma PF03276.14 OAI96509.1 - 0.078 11.4 0.4 0.088 11.2 0.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Asn_synthase PF00733.21 OAI96518.1 - 8.7e-10 38.8 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase HTH_Tnp_1 PF01527.20 OAI96520.1 - 0.007 16.7 0.0 0.022 15.1 0.0 1.8 1 0 0 1 1 1 1 Transposase HTH_28 PF13518.6 OAI96520.1 - 0.031 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 OAI96520.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain SYF2 PF08231.12 OAI96524.1 - 0.2 12.0 9.1 0.48 10.8 4.1 2.3 1 1 1 2 2 2 0 SYF2 splicing factor DUF4473 PF14747.6 OAI96527.1 - 0.12 13.0 0.1 0.21 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Nif11 PF07862.11 OAI96531.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain PilO PF04350.13 OAI96531.1 - 0.047 13.9 1.0 0.057 13.6 1.0 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO MMPL PF03176.15 OAI96531.1 - 0.11 11.4 0.2 0.12 11.3 0.2 1.0 1 0 0 1 1 1 0 MMPL family WD40 PF00400.32 OAI96532.1 - 3.6e-30 103.5 3.2 8.5e-07 29.6 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI96532.1 - 2.7e-07 30.8 0.0 0.0095 16.2 0.0 3.0 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAI96532.1 - 0.015 14.0 0.8 0.3 9.7 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Barstar PF01337.18 OAI96538.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Coatomer_WDAD PF04053.14 OAI96543.1 - 7.7e-29 101.0 0.0 1e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region GW PF13457.6 OAI96546.1 - 0.019 15.6 0.3 0.027 15.1 0.3 1.4 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain Borrelia_P83 PF05262.11 OAI96551.1 - 6.5 5.1 25.2 6.4 5.1 25.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SOBP PF15279.6 OAI96551.1 - 9.7 6.7 8.6 12 6.4 8.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Retrotrans_gag PF03732.17 OAI96558.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein TAP_C PF03943.13 OAI96567.1 - 3.9e-14 52.0 0.1 5.7e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain DDE_Tnp_4 PF13359.6 OAI96573.1 - 1.6e-19 70.1 0.0 3.8e-19 68.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease PEMT PF04191.13 OAI96581.1 - 1.4e-35 121.8 5.3 1.4e-35 121.8 5.3 1.4 2 0 0 2 2 2 1 Phospholipid methyltransferase Merozoite_SPAM PF07133.11 OAI96590.1 - 0.079 12.9 22.0 0.094 12.7 22.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF3464 PF11947.8 OAI96590.1 - 0.18 11.6 3.2 0.25 11.1 3.2 1.4 1 1 0 1 1 1 0 Photosynthesis affected mutant 68 Hydin_ADK PF17213.3 OAI96590.1 - 0.56 10.5 5.8 0.71 10.1 5.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Rav1p_C PF12234.8 OAI96590.1 - 1.3 7.3 5.8 1.4 7.2 5.8 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal MCRS_N PF13325.6 OAI96590.1 - 3.7 7.5 13.7 4.9 7.1 13.7 1.1 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein CDC45 PF02724.14 OAI96590.1 - 7.3 4.8 13.6 7.5 4.7 13.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SNARE PF05739.19 OAI96602.1 - 0.11 12.5 0.3 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 SNARE domain CD225 PF04505.12 OAI96602.1 - 0.55 10.4 3.7 1.3 9.2 3.7 1.8 1 1 0 1 1 1 0 Interferon-induced transmembrane protein Fructosamin_kin PF03881.14 OAI96613.1 - 2.3e-60 204.2 0.0 3.6e-60 203.6 0.0 1.3 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 OAI96613.1 - 8.2e-07 29.2 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family UCH PF00443.29 OAI96616.1 - 0.21 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Histone_H2A_C PF16211.5 OAI96619.1 - 2.1e-18 65.7 0.8 4.8e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAI96619.1 - 2.1e-13 50.8 0.0 2.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RRM_1 PF00076.22 OAI96626.1 - 2e-10 40.4 0.0 5.6e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 OAI96626.1 - 0.0044 17.6 3.8 0.011 16.3 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) Rpn3_C PF08375.11 OAI96626.1 - 0.47 10.9 3.4 6.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal YL1_C PF08265.11 OAI96627.1 - 9.9e-14 50.8 0.6 1.6e-13 50.2 0.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Pyr_redox_2 PF07992.14 OAI96635.1 - 1.2e-14 54.2 0.0 4.2e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI96635.1 - 2.1e-12 47.0 0.6 8.7e-12 44.9 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAI96635.1 - 8.1e-11 41.0 0.0 1.3e-09 37.0 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAI96635.1 - 4.5e-08 33.2 0.0 9.3e-07 29.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAI96635.1 - 3.8e-07 30.0 2.3 0.0025 17.4 0.1 3.7 3 2 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAI96635.1 - 6.6e-07 28.8 0.1 0.003 16.7 0.0 3.1 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 OAI96635.1 - 1.7e-06 27.5 0.0 1.2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 OAI96635.1 - 0.00053 19.2 0.1 0.0021 17.2 0.0 2.0 3 0 0 3 3 3 1 FAD binding domain Mqo PF06039.15 OAI96635.1 - 0.00065 18.4 0.1 0.27 9.7 0.0 2.6 2 1 1 3 3 3 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 OAI96635.1 - 0.0012 18.8 0.7 1.7 8.6 0.1 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAI96635.1 - 0.0025 16.9 0.3 0.54 9.3 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 OAI96635.1 - 0.0054 17.3 0.0 9.1 6.9 0.1 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAI96635.1 - 0.021 14.9 0.0 2.2 8.3 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 OAI96635.1 - 0.028 13.5 0.2 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 OAI96635.1 - 0.04 13.3 0.2 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAI96635.1 - 0.068 12.4 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 OAI96635.1 - 0.21 10.2 0.3 0.86 8.2 0.1 2.1 3 0 0 3 3 3 0 HI0933-like protein Hydrolase_4 PF12146.8 OAI96636.1 - 0.0033 16.7 0.0 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 OAI96636.1 - 0.0038 17.0 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OAI96636.1 - 0.0048 17.5 0.5 0.025 15.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAI96636.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAI96636.1 - 0.08 12.8 0.1 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 OAI96636.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF148 PF02520.17 OAI96639.1 - 0.093 12.8 0.5 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Peptidase_S64 PF08192.11 OAI96639.1 - 2.4 6.6 17.8 0.65 8.4 10.5 2.0 2 0 0 2 2 2 0 Peptidase family S64 SLC12 PF03522.15 OAI96639.1 - 6.6 5.6 17.0 0.26 10.3 6.6 2.1 2 0 0 2 2 2 0 Solute carrier family 12 MMS19_C PF12460.8 OAI96642.1 - 1.1e-10 41.3 0.1 1.4e-09 37.6 0.1 1.9 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 OAI96642.1 - 0.019 15.2 2.5 0.17 12.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 OAI96642.1 - 0.24 11.8 2.6 4.2 7.8 0.5 2.4 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 OAI96642.1 - 0.66 10.5 3.2 3.8 8.1 0.3 2.5 2 0 0 2 2 2 0 HEAT-like repeat RVT_1 PF00078.27 OAI96648.1 - 2.3e-24 86.1 0.0 3.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Trypsin_2 PF13365.6 OAI96656.1 - 1.6e-05 25.9 0.0 0.0092 16.9 0.0 2.6 2 1 0 2 2 2 2 Trypsin-like peptidase domain ORC6 PF05460.13 OAI96660.1 - 3.4 6.9 7.7 0.098 11.9 1.3 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Phosducin PF02114.16 OAI96667.1 - 1.6e-08 33.8 0.1 3.5e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Phosducin GOLD_2 PF13897.6 OAI96667.1 - 6.4 7.3 6.1 0.55 10.7 0.5 1.9 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Cwf_Cwc_15 PF04889.12 OAI96667.1 - 6.8 6.3 13.2 0.49 10.1 5.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DDE_1 PF03184.19 OAI96669.1 - 9.4e-19 67.7 0.0 1.7e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAI96669.1 - 5.5e-06 26.3 0.0 4.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAI96669.1 - 0.0027 17.5 0.0 0.0027 17.5 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease AAA_17 PF13207.6 OAI96669.1 - 0.24 11.8 5.2 0.78 10.2 5.2 1.9 1 0 0 1 1 1 0 AAA domain Apolipoprotein PF01442.18 OAI96675.1 - 0.0002 21.3 0.7 0.00031 20.7 0.7 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 OAI96675.1 - 0.055 14.1 0.1 0.055 14.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LysR_substrate PF03466.20 OAI96677.1 - 1.3e-24 86.8 1.1 1.9e-24 86.2 1.1 1.2 1 0 0 1 1 1 1 LysR substrate binding domain HTH_1 PF00126.27 OAI96677.1 - 1.7e-20 72.7 1.5 2.1e-20 72.4 0.3 1.8 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix protein, lysR family MarR_2 PF12802.7 OAI96677.1 - 0.019 14.9 0.2 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 MarR family HTH_24 PF13412.6 OAI96677.1 - 0.073 12.6 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 OAI96677.1 - 0.18 11.8 0.3 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 MarR family DUF3905 PF13045.6 OAI96678.1 - 0.17 11.9 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) LysR_substrate PF03466.20 OAI96679.1 - 1.1e-13 51.1 1.6 1.2e-13 50.9 1.6 1.0 1 0 0 1 1 1 1 LysR substrate binding domain IlvN PF07991.12 OAI96683.1 - 9.5e-47 158.6 0.0 2.1e-46 157.5 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 OAI96683.1 - 1.3e-39 135.8 0.0 2.1e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Oxidored_nitro PF00148.19 OAI96683.1 - 0.049 12.4 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.17 OAI96683.1 - 0.076 13.6 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAI96683.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Dicty_REP PF05086.12 OAI96689.1 - 0.23 9.4 0.9 0.23 9.4 0.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.9 OAI96689.1 - 1.3 8.6 6.5 1.7 8.2 6.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_2 PF00891.18 OAI96693.1 - 9.3e-20 70.8 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OAI96693.1 - 0.00039 21.1 0.0 0.00091 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3678 PF12435.8 OAI96693.1 - 0.0046 16.3 0.1 0.015 14.6 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3678) Methyltransf_25 PF13649.6 OAI96693.1 - 0.008 16.9 0.0 0.024 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HTH_AraC PF00165.23 OAI96693.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Rrf2 PF02082.20 OAI96693.1 - 0.073 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.11 OAI96693.1 - 0.094 13.4 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_31 PF13847.6 OAI96693.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MULE PF10551.9 OAI96697.1 - 1.5e-11 44.5 0.4 2.7e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAI96697.1 - 0.0025 17.8 0.1 0.0048 16.9 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase E1-E2_ATPase PF00122.20 OAI96704.1 - 0.11 12.0 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Hydrolase PF00702.26 OAI96705.1 - 6.7e-05 23.3 0.2 0.00011 22.6 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAI96705.1 - 0.0018 18.1 0.2 0.0027 17.5 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pro_isomerase PF00160.21 OAI96711.1 - 2e-49 167.9 0.4 2.5e-49 167.6 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2 PF00152.20 OAI96716.1 - 4.1e-35 121.4 0.1 4.1e-35 121.4 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAI96716.1 - 8.7e-06 25.6 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mito_carr PF00153.27 OAI96727.1 - 1.8e-12 47.0 0.4 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein RVT_3 PF13456.6 OAI96730.1 - 0.00085 19.1 0.2 0.0018 18.1 0.2 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 OAI96730.1 - 0.083 12.4 0.0 0.23 10.9 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NEMP PF10225.9 OAI96743.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 NEMP family DUF4834 PF16118.5 OAI96743.1 - 0.037 15.0 0.0 0.047 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Peptidase_M43 PF05572.13 OAI96745.1 - 4.1e-11 43.0 0.0 7e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAI96745.1 - 0.00038 21.0 1.3 0.0076 16.8 1.3 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAI96745.1 - 0.0011 19.2 0.6 0.0015 18.7 0.6 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAI96745.1 - 0.0096 15.6 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAI96745.1 - 0.017 15.0 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M7 PF02031.16 OAI96745.1 - 0.028 14.5 1.5 0.051 13.7 0.7 1.8 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family DUF4953 PF16313.5 OAI96745.1 - 0.14 11.3 0.8 0.23 10.6 0.8 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M57 PF12388.8 OAI96745.1 - 0.33 10.5 2.0 7 6.2 0.5 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 OAI96745.1 - 0.42 10.6 0.7 1.1 9.2 0.7 1.7 1 1 0 1 1 1 0 Peptidase family M54 Abhydrolase_1 PF00561.20 OAI96751.1 - 0.00038 20.2 0.2 0.083 12.5 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAI96751.1 - 0.00058 19.2 0.0 0.29 10.4 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 OAI96751.1 - 0.022 14.3 1.3 0.57 9.7 0.1 2.5 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) VID27 PF08553.10 OAI96754.1 - 7.2e-114 380.5 0.0 8.2e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain TPR_2 PF07719.17 OAI96755.1 - 5.6e-05 23.0 12.5 4.2 7.7 0.1 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAI96755.1 - 0.0013 18.5 17.2 3.7 7.6 0.0 6.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAI96755.1 - 0.0022 17.7 0.9 4.7 7.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAI96755.1 - 0.39 11.4 5.6 6.8 7.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAI96755.1 - 0.58 10.5 6.5 7.6 7.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAI96755.1 - 1.4 9.6 10.0 7.6 7.3 0.3 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAI96755.1 - 8.9 6.7 31.3 1.1 9.6 2.0 7.1 7 2 2 9 9 9 0 Tetratricopeptide repeat tRNA-synt_1 PF00133.22 OAI96757.1 - 2.2e-54 184.8 0.0 3.2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAI96757.1 - 3.9e-22 78.9 0.0 6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAI96757.1 - 0.0012 17.6 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 OAI96757.1 - 0.0079 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF3658 PF12395.8 OAI96757.1 - 0.097 12.6 0.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function Hydrolase PF00702.26 OAI96763.1 - 0.00034 21.0 0.0 0.00049 20.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAI96763.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) SARAF PF06682.12 OAI96763.1 - 5 6.7 8.9 8.2 6.0 8.9 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis LRR_9 PF14580.6 OAI96767.1 - 0.34 10.4 1.5 9.7 5.7 0.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeat LSM PF01423.22 OAI96776.1 - 1.3e-18 66.4 0.4 1.9e-18 65.9 0.4 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAI96776.1 - 0.014 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Hfq protein PTPA PF03095.15 OAI96777.1 - 2.1e-91 306.5 0.0 2.5e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Oxidored_q2 PF00420.24 OAI96780.1 - 0.94 9.1 4.2 15 5.3 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Viral_helicase1 PF01443.18 OAI96787.1 - 4.9e-15 55.9 0.0 6.4e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAI96787.1 - 0.087 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAI96787.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAI96787.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ETX_MTX2 PF03318.13 OAI96787.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 DUF1682 PF07946.14 OAI96797.1 - 0.54 9.4 7.7 0.73 9.0 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) GREB1 PF15782.5 OAI96797.1 - 5.6 3.9 8.9 7.1 3.6 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF724 PF05266.14 OAI96797.1 - 9.6 6.0 10.9 18 5.1 10.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pyr_redox_2 PF07992.14 OAI96802.1 - 2e-51 175.0 0.3 2.3e-51 174.8 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAI96802.1 - 1.6e-18 67.0 0.1 1.3e-15 57.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI96802.1 - 7.6e-18 64.8 0.4 3.6e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAI96802.1 - 4.3e-06 26.3 0.1 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 OAI96802.1 - 7.2e-06 25.4 0.0 0.00015 21.1 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 OAI96802.1 - 2.7e-05 23.5 2.0 0.0064 15.6 0.1 3.5 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAI96802.1 - 2.9e-05 23.5 0.2 0.024 13.9 0.0 3.0 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAI96802.1 - 0.00011 22.3 0.4 0.014 15.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 OAI96802.1 - 0.0003 21.2 0.1 0.021 15.3 0.0 2.8 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 OAI96802.1 - 0.0019 17.4 3.8 0.0061 15.7 0.5 2.5 2 1 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 OAI96802.1 - 0.0045 15.9 0.1 0.064 12.1 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 OAI96802.1 - 0.005 15.6 0.1 0.033 12.9 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.20 OAI96802.1 - 0.009 16.1 0.0 7.4 6.6 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 OAI96802.1 - 0.011 14.9 0.1 0.56 9.3 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAI96802.1 - 0.016 14.8 4.6 0.12 11.9 0.3 3.1 1 1 1 3 3 3 0 FAD dependent oxidoreductase Sec15 PF04091.12 OAI96807.1 - 1.7e-44 152.5 0.0 2.2e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like GFO_IDH_MocA_C PF02894.17 OAI96807.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain IcmF_C PF06744.12 OAI96807.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal DUF11 PF01345.18 OAI96811.1 - 0.045 14.1 4.1 6.5 7.1 1.2 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 DUF3288 PF11691.8 OAI96813.1 - 0.037 14.1 0.1 0.95 9.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3288) PSK_trans_fac PF07704.11 OAI96813.1 - 0.22 12.3 1.2 0.31 11.8 0.5 1.9 2 1 0 2 2 2 0 Rv0623-like transcription factor RVT_1 PF00078.27 OAI96819.1 - 9.2e-29 100.5 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PAD_porph PF04371.15 OAI96822.1 - 0.015 14.6 0.3 0.83 8.9 0.0 2.1 1 1 0 2 2 2 0 Porphyromonas-type peptidyl-arginine deiminase Methyltransf_4 PF02390.17 OAI96825.1 - 2.4e-49 167.1 0.0 5.1e-37 127.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase SUIM_assoc PF16619.5 OAI96825.1 - 0.013 15.6 0.1 0.033 14.3 0.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Methyltransf_12 PF08242.12 OAI96825.1 - 0.016 15.9 0.0 0.059 14.1 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAI96825.1 - 0.027 15.2 0.1 0.26 12.0 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Glycos_transf_2 PF00535.26 OAI96825.1 - 0.1 12.4 0.0 0.29 10.9 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF913 PF06025.12 OAI96825.1 - 0.21 10.5 0.4 0.34 9.8 0.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Collagen PF01391.18 OAI96827.1 - 2.5e-23 81.6 82.0 1.6e-10 40.6 39.6 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) CH PF00307.31 OAI96831.1 - 8.9e-06 25.9 0.1 1.1e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 OAI96831.1 - 0.021 15.0 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Yos1 PF08571.10 OAI96832.1 - 4.5e-30 103.7 0.9 6.2e-30 103.3 0.9 1.2 1 0 0 1 1 1 1 Yos1-like HNH PF01844.23 OAI96839.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.5 3 0 0 3 3 3 0 HNH endonuclease Exo_endo_phos_2 PF14529.6 OAI96841.1 - 2.3e-12 46.8 0.0 5.2e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAI96841.1 - 1.7e-05 24.5 0.1 3.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NIT PF08376.10 OAI96841.1 - 0.024 15.1 0.3 0.024 15.1 0.3 2.4 2 1 1 3 3 3 0 Nitrate and nitrite sensing RVT_1 PF00078.27 OAI96841.1 - 0.15 11.6 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAI96843.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAI96843.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAI96843.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like AMP-binding PF00501.28 OAI96849.1 - 8.8e-06 24.6 0.0 1.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAI96849.1 - 9.2e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Actin PF00022.19 OAI96855.1 - 6.1e-149 496.1 0.0 2.8e-148 493.9 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 OAI96855.1 - 0.018 13.6 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase BLOC1_2 PF10046.9 OAI96859.1 - 0.065 13.5 4.4 0.084 13.2 3.9 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSP70 PF00012.20 OAI96859.1 - 0.33 9.1 7.7 0.38 8.9 7.7 1.0 1 0 0 1 1 1 0 Hsp70 protein XkdW PF09636.10 OAI96859.1 - 0.94 9.6 8.4 0.38 10.9 1.7 2.1 1 1 1 2 2 2 0 XkdW protein U79_P34 PF03064.16 OAI96859.1 - 0.98 8.7 11.6 1.4 8.2 11.6 1.4 1 1 0 1 1 1 0 HSV U79 / HCMV P34 Spc7 PF08317.11 OAI96859.1 - 1.3 7.9 11.9 1.5 7.6 11.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein MatP_C PF17414.2 OAI96859.1 - 1.7 8.9 6.4 1.2 9.4 2.4 2.3 1 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain KDZ PF18758.1 OAI96867.1 - 2.9e-07 30.4 0.5 4.2e-07 29.8 0.5 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FHA PF00498.26 OAI96870.1 - 0.075 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 FHA domain FHA PF00498.26 OAI96876.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 FHA domain adh_short PF00106.25 OAI96879.1 - 8e-07 28.7 0.0 3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 OAI96879.1 - 0.016 15.1 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 KR domain rve PF00665.26 OAI96886.1 - 4.6e-15 55.9 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI96886.1 - 7.3e-09 35.6 0.2 1.5e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAI96886.1 - 0.00026 20.7 0.0 0.0016 18.2 0.0 2.4 1 0 0 1 1 1 1 Integrase core domain Histone PF00125.24 OAI96898.1 - 1.7e-22 80.2 0.8 1.9e-22 80.0 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OAI96898.1 - 0.0027 18.3 2.4 0.0033 18.0 2.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain BON PF04972.17 OAI96898.1 - 0.039 14.3 0.1 0.084 13.2 0.1 1.5 1 0 0 1 1 1 0 BON domain DUF45 PF01863.17 OAI96914.1 - 2.6e-48 164.8 0.1 9.4e-48 163.0 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 WLM PF08325.10 OAI96914.1 - 1.7e-05 25.0 0.1 5e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 WLM domain SprT-like PF10263.9 OAI96914.1 - 0.0004 20.2 0.2 0.0011 18.8 0.2 1.7 1 0 0 1 1 1 1 SprT-like family Helo_like_N PF17111.5 OAI96914.1 - 0.0016 17.9 0.2 0.0031 16.9 0.2 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins RimK PF08443.11 OAI96914.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain DUF1320 PF07030.12 OAI96914.1 - 0.16 12.1 4.2 13 5.9 0.1 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1320) Com_YlbF PF06133.11 OAI96914.1 - 0.32 11.6 3.0 1.1 9.9 0.2 2.8 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA MS_channel PF00924.18 OAI96917.1 - 7.6e-11 41.9 6.0 8.8e-09 35.2 6.0 2.2 1 1 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAI96917.1 - 0.042 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAI96917.1 - 0.15 12.1 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Transposase_21 PF02992.14 OAI96920.1 - 0.00027 20.3 0.0 0.00048 19.4 0.0 1.5 2 0 0 2 2 2 1 Transposase family tnp2 RVT_1 PF00078.27 OAI96923.1 - 3e-14 53.1 0.0 4.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAI96923.1 - 1.5e-07 31.6 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAI96923.1 - 2.5e-06 27.3 0.0 6.5e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like SRF-TF PF00319.18 OAI96923.1 - 0.021 14.3 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1232 PF06803.12 OAI96923.1 - 0.099 12.5 2.1 0.23 11.3 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) SR-25 PF10500.9 OAI96927.1 - 0.11 12.1 5.7 0.13 11.8 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3682 PF12446.8 OAI96927.1 - 0.12 12.8 5.7 0.16 12.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) His_Phos_1 PF00300.22 OAI96928.1 - 2.4e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SAM_decarbox PF01536.16 OAI96936.1 - 1.5e-115 386.0 0.0 2.2e-115 385.4 0.0 1.3 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase MMU163 PF17119.5 OAI96938.1 - 6.3 5.9 8.1 12 5.0 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis EF-hand_10 PF14788.6 OAI96939.1 - 0.016 15.0 0.2 0.035 13.9 0.2 1.5 1 0 0 1 1 1 0 EF hand SLATT_fungal PF18142.1 OAI96939.1 - 0.021 14.8 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain HBS1_N PF08938.10 OAI96939.1 - 0.031 14.6 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 HBS1 N-terminus EcoR124_C PF12008.8 OAI96939.1 - 0.033 13.8 0.0 0.039 13.6 0.0 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal GP24_25 PF17388.2 OAI96939.1 - 0.048 13.6 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 RRM_1 PF00076.22 OAI96941.1 - 1.4e-36 124.2 0.0 3.6e-16 58.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NOA36 PF06524.12 OAI96941.1 - 0.087 12.1 27.3 0.18 11.1 27.3 1.4 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 OAI96941.1 - 0.093 12.1 25.1 0.29 10.5 25.1 1.8 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 OAI96941.1 - 0.35 10.4 25.7 0.7 9.4 25.7 1.4 1 0 0 1 1 1 0 PPP4R2 Nop25 PF09805.9 OAI96941.1 - 0.61 10.5 26.7 0.02 15.4 18.4 2.6 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) PIEZO PF15917.5 OAI96941.1 - 1 8.8 9.9 0.13 11.7 5.8 1.6 2 0 0 2 2 2 0 Piezo Nop14 PF04147.12 OAI96941.1 - 1.2 7.2 30.0 1.9 6.6 30.0 1.2 1 0 0 1 1 1 0 Nop14-like family Phage_integrase PF00589.22 OAI96946.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family BCDHK_Adom3 PF10436.9 OAI96952.1 - 1.2e-05 25.3 0.2 1.8e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Mito_carr PF00153.27 OAI96956.1 - 1.4e-61 204.4 6.3 7.8e-21 73.8 0.0 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF5331 PF17265.2 OAI96956.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Retrotrans_gag PF03732.17 OAI96958.1 - 0.033 14.5 0.1 0.096 13.0 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Zn_clus PF00172.18 OAI96961.1 - 0.00051 20.1 15.1 0.00075 19.6 15.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain U3snoRNP10 PF12397.8 OAI96966.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 Methyltransf_2 PF00891.18 OAI96969.1 - 5.1e-11 42.3 0.0 8.9e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain DUF3678 PF12435.8 OAI96969.1 - 0.022 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DDE_1 PF03184.19 OAI96974.1 - 2.4e-18 66.4 0.1 1.2e-17 64.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAI96974.1 - 6.9e-08 32.4 2.5 1.4e-07 31.5 0.1 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAI96974.1 - 0.0013 18.5 0.0 0.0089 15.8 0.0 2.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF5338 PF17273.2 OAI96974.1 - 0.13 12.3 2.1 5 7.3 1.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5338) ECSIT_C PF14784.6 OAI96974.1 - 0.84 10.0 3.1 8.2 6.8 0.0 3.1 3 0 0 3 3 3 0 C-terminal domain of the ECSIT protein Integrase_H2C2 PF17921.1 OAI96977.1 - 2.7e-14 53.0 0.0 5.1e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI96977.1 - 2.1e-13 50.4 0.0 9.8e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI96977.1 - 1.5e-10 41.0 0.0 1.2e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI96977.1 - 4.3e-10 39.8 0.0 1.2e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain PfkB PF00294.24 OAI96986.1 - 9.2e-61 205.8 0.3 1.1e-60 205.5 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 OAI96986.1 - 0.0031 17.0 0.0 0.0069 15.8 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF3772 PF12607.8 OAI96991.1 - 0.059 13.1 4.9 0.4 10.5 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) MULE PF10551.9 OAI96993.1 - 2.4e-06 27.9 0.0 1.1e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain His_binding PF02098.16 OAI96993.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Tick histamine binding protein TrkA_N PF02254.18 OAI96993.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HTH_29 PF13551.6 OAI96993.1 - 0.13 12.3 1.5 0.24 11.5 0.1 2.2 2 1 1 3 3 3 0 Winged helix-turn helix rve PF00665.26 OAI96996.1 - 5.5e-16 58.8 0.0 1.3e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI96996.1 - 7.3e-12 45.2 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAI96996.1 - 0.013 15.2 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.14 OAI97003.1 - 8e-61 205.7 0.0 1.1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI97003.1 - 0.31 10.8 2.6 4.8 7.0 1.3 2.7 2 1 0 2 2 2 0 Reverse transcriptase-like DUF726 PF05277.12 OAI97012.1 - 1.2e-62 211.9 0.0 1.7e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Apolipoprotein PF01442.18 OAI97017.1 - 0.024 14.5 1.6 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain P66_CC PF16563.5 OAI97017.1 - 0.056 13.1 1.6 0.1 12.3 1.6 1.4 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 HalX PF08663.10 OAI97017.1 - 0.15 12.4 2.6 0.76 10.1 2.6 2.2 1 1 0 1 1 1 0 HalX domain Antimicrobial25 PF16839.5 OAI97022.1 - 0.12 12.5 0.7 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Nematode antimicrobial peptide Peptidase_S10 PF00450.22 OAI97025.1 - 1e-70 239.3 0.0 1.4e-70 238.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MT-A70 PF05063.14 OAI97029.1 - 1.9e-06 27.9 0.0 0.0031 17.5 0.1 3.1 2 1 0 2 2 2 2 MT-A70 DEC-1_N PF04625.13 OAI97044.1 - 0.37 9.8 11.7 0.53 9.2 11.7 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region P35 PF02331.15 OAI97046.1 - 0.047 13.0 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein Sec1 PF00995.23 OAI97055.1 - 6e-83 280.0 0.0 7.9e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Peptidase_C48 PF02902.19 OAI97059.1 - 7.6e-08 32.5 0.5 6.5e-07 29.4 0.0 2.4 1 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.32 OAI97060.1 - 0.016 16.0 16.9 0.23 12.4 0.2 4.6 4 2 0 4 4 4 0 WD domain, G-beta repeat CENP-B_dimeris PF09026.10 OAI97060.1 - 0.46 10.9 9.7 1.1 9.7 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SWIM PF04434.17 OAI97064.1 - 0.0011 18.5 0.5 0.002 17.8 0.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger Asp_protease_2 PF13650.6 OAI97072.1 - 0.00084 19.9 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAI97072.1 - 0.0038 16.8 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 OAI97072.1 - 0.0074 16.8 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease HSBP1 PF06825.12 OAI97084.1 - 9.1e-16 57.5 0.4 1e-15 57.3 0.4 1.0 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Fzo_mitofusin PF04799.13 OAI97084.1 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 fzo-like conserved region DUF1515 PF07439.11 OAI97084.1 - 0.037 14.0 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) CLZ PF16526.5 OAI97084.1 - 0.065 13.6 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Matrilin_ccoil PF10393.9 OAI97084.1 - 0.082 12.8 0.3 0.13 12.2 0.3 1.5 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin PXB PF12828.7 OAI97085.1 - 2.7e-40 137.4 0.4 4.3e-40 136.7 0.4 1.3 1 0 0 1 1 1 1 PX-associated PX PF00787.24 OAI97085.1 - 9.9e-06 25.5 0.1 3.9e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 PX domain Integrase_H2C2 PF17921.1 OAI97088.1 - 1.3e-19 70.1 0.7 2.4e-19 69.2 0.7 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI97088.1 - 1.3e-17 64.0 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI97088.1 - 9.6e-12 44.8 0.0 2.4e-11 43.6 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI97088.1 - 1.4e-08 35.0 0.0 2.7e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAI97088.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Cupin_4 PF08007.12 OAI97091.1 - 3.7e-47 161.4 0.1 4.6e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 OAI97091.1 - 9e-11 42.0 0.3 2.6e-08 33.9 0.1 3.0 1 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.11 OAI97091.1 - 0.048 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Phage_tail_U PF06141.11 OAI97097.1 - 0.035 14.5 0.0 0.06 13.7 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein U Y1_Tnp PF01797.16 OAI97097.1 - 0.075 13.1 0.5 0.15 12.2 0.5 1.5 1 1 0 1 1 1 0 Transposase IS200 like ADH_zinc_N_2 PF13602.6 OAI97109.1 - 5.7e-18 66.3 0.0 1.4e-17 64.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAI97109.1 - 9e-18 64.5 0.3 1.4e-17 63.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAI97109.1 - 7.4e-09 35.5 0.0 2.1e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CMAS PF02353.20 OAI97109.1 - 0.068 12.5 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SSB PF00436.25 OAI97109.1 - 0.077 13.0 0.2 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Single-strand binding protein family ADH_zinc_N_2 PF13602.6 OAI97112.1 - 3.8e-15 57.1 0.0 9.2e-14 52.6 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAI97112.1 - 1.2e-14 54.4 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.22 OAI97112.1 - 0.004 17.1 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 DeoR C terminal sensor domain ADH_N PF08240.12 OAI97112.1 - 0.0097 15.8 0.0 0.064 13.1 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAI97112.1 - 0.13 12.2 0.1 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase MitMem_reg PF13012.6 OAI97125.1 - 2.8e-28 98.6 0.4 7.7e-28 97.2 0.2 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAI97125.1 - 5.5e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNase_PH PF01138.21 OAI97128.1 - 2.7e-16 60.3 0.0 4.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3Beta_HSD PF01073.19 OAI97129.1 - 7.9e-19 67.7 0.0 3.3e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAI97129.1 - 6.9e-14 51.9 0.1 1.3e-13 51.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 OAI97129.1 - 2.7e-12 46.4 0.8 8.1e-11 41.6 0.8 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAI97129.1 - 4.6e-11 43.0 0.1 6.9e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAI97129.1 - 4.8e-08 32.8 0.1 9.6e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAI97129.1 - 1.3e-07 31.4 0.2 2.1e-07 30.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 OAI97129.1 - 2.2e-05 24.0 1.0 0.037 13.5 0.1 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 OAI97129.1 - 6.4e-05 22.2 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 OAI97129.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 OAI97129.1 - 0.0099 16.1 0.1 0.023 14.9 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 OAI97129.1 - 0.041 13.8 0.5 0.76 9.7 0.5 2.2 1 1 0 1 1 1 0 KR domain ACPS PF01648.20 OAI97133.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DNA_pol_viral_C PF00336.18 OAI97137.1 - 0.0085 15.5 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAI97138.1 - 6.2e-05 22.8 0.0 9.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI97138.1 - 0.2 11.5 0.6 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) FHA PF00498.26 OAI97143.1 - 0.09 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 FHA domain RmlD_sub_bind PF04321.17 OAI97150.1 - 0.039 13.1 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DHHW PF14286.6 OAI97150.1 - 0.11 11.8 1.6 0.12 11.6 1.6 1.1 1 0 0 1 1 1 0 DHHW protein SR-25 PF10500.9 OAI97150.1 - 0.26 10.8 16.9 0.34 10.5 16.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 OAI97150.1 - 1.5 7.3 7.7 1.9 7.0 7.7 1.0 1 0 0 1 1 1 0 Macoilin family Ccdc124 PF06244.12 OAI97152.1 - 2.4e-16 60.5 0.1 1.9e-12 47.8 0.1 2.2 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 124 /Oxs1 CMS1 PF14617.6 OAI97156.1 - 1.8e-18 66.8 3.6 8.9e-07 28.5 0.0 4.2 2 2 1 3 3 3 3 U3-containing 90S pre-ribosomal complex subunit BBE PF08031.12 OAI97157.1 - 0.00075 19.6 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Berberine and berberine like DUF4218 PF13960.6 OAI97165.1 - 0.14 11.8 0.1 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Histone PF00125.24 OAI97166.1 - 4.3e-47 159.7 0.2 5.5e-47 159.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAI97166.1 - 0.00082 19.5 0.3 0.0016 18.5 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAI97166.1 - 0.0015 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein MannoseP_isomer PF01050.18 OAI97166.1 - 0.087 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase SR-25 PF10500.9 OAI97173.1 - 0.05 13.2 11.5 0.72 9.4 0.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BATS PF06968.13 OAI97179.1 - 3.1e-19 68.9 0.1 1.6e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 OAI97179.1 - 8.3e-13 49.1 0.1 1.4e-12 48.4 0.1 1.3 1 0 0 1 1 1 1 Radical SAM superfamily IFRD_C PF04836.12 OAI97182.1 - 0.058 14.0 0.0 0.18 12.4 0.0 1.9 1 0 0 1 1 1 0 Interferon-related protein conserved region ESX-1_EspG PF14011.6 OAI97186.1 - 0.13 11.9 0.7 0.42 10.2 0.1 1.8 1 1 1 2 2 2 0 EspG family Phage_int_SAM_1 PF02899.17 OAI97187.1 - 0.077 13.3 0.0 0.35 11.2 0.0 2.1 2 1 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Aldedh PF00171.22 OAI97192.1 - 1.3e-10 40.5 0.0 1.3e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family CRR7 PF12095.8 OAI97192.1 - 0.094 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 tRNA_NucTransf2 PF09249.11 OAI97196.1 - 0.19 12.0 0.1 0.28 11.4 0.1 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain DUF515 PF04415.12 OAI97208.1 - 0.57 8.5 6.4 0.76 8.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.25 OAI97213.1 - 6.1e-19 68.4 0.0 6.6e-09 35.5 0.0 4.1 2 2 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97213.1 - 4.3e-11 42.6 0.0 7e-08 32.1 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 OAI97213.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chlam_PMP PF02415.17 OAI97213.1 - 0.2 12.2 10.0 4 8.1 0.0 5.2 4 1 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pinin_SDK_N PF04697.13 OAI97213.1 - 4.4 7.9 6.9 5.7 7.6 2.7 2.5 2 0 0 2 2 2 0 pinin/SDK conserved region KOW PF00467.29 OAI97222.1 - 0.00053 19.8 0.5 0.00053 19.8 0.5 2.5 3 0 0 3 3 3 1 KOW motif CTD PF12815.7 OAI97222.1 - 0.024 15.2 59.2 0.3 11.7 13.0 5.3 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 FAD_binding_8 PF08022.12 OAI97227.1 - 1.2e-18 67.2 0.0 2.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAI97227.1 - 9.6e-15 55.0 0.0 2e-13 50.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAI97227.1 - 6.7e-11 42.4 5.8 1.8e-10 41.0 5.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Phage_integrase PF00589.22 OAI97231.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family FAD_binding_4 PF01565.23 OAI97236.1 - 7.8e-23 80.8 1.7 3.6e-22 78.6 1.4 2.0 2 0 0 2 2 2 1 FAD binding domain RVT_1 PF00078.27 OAI97240.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAI97240.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.17 OAI97240.1 - 0.31 11.3 1.7 0.62 10.4 0.1 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.23 OAI97240.1 - 0.51 10.5 4.0 0.23 11.6 1.5 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAI97240.1 - 0.89 9.3 3.5 8.9 6.1 2.2 2.5 2 0 0 2 2 2 0 Zinc knuckle CENP-B_dimeris PF09026.10 OAI97243.1 - 0.1 13.0 7.0 0.23 11.9 7.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAI97243.1 - 0.48 9.7 2.5 0.77 9.0 2.5 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAI97243.1 - 2 6.4 4.6 2.8 5.9 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OAI97243.1 - 2.8 7.6 4.4 5.5 6.6 3.6 1.8 2 0 0 2 2 2 0 FAM176 family Nop25 PF09805.9 OAI97243.1 - 6.2 7.3 8.5 0.77 10.2 2.1 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) zf-CCHC PF00098.23 OAI97250.1 - 0.00091 19.2 3.5 0.0017 18.3 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAI97250.1 - 0.38 10.6 4.4 0.75 9.7 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 OAI97254.1 - 1.4e-54 185.2 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97254.1 - 8.5e-31 107.2 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI97254.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAI97254.1 - 1e-05 24.5 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAI97254.1 - 0.00043 19.7 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAI97254.1 - 0.0028 17.6 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S4e PF00900.20 OAI97254.1 - 0.094 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal family S4e Pox_ser-thr_kin PF05445.11 OAI97254.1 - 0.14 11.1 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Helicase_C PF00271.31 OAI97259.1 - 2.1e-07 31.3 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAI97259.1 - 0.031 14.1 0.0 0.32 10.8 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase MCM PF00493.23 OAI97264.1 - 1e-30 106.5 0.1 1.2e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 OAI97264.1 - 0.021 14.2 0.1 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MCM PF00493.23 OAI97265.1 - 1.4e-35 122.4 0.0 1.8e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAI97265.1 - 2.5e-27 95.2 0.0 3.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 OAI97266.1 - 6.1e-13 49.2 0.0 9.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain FAD_binding_4 PF01565.23 OAI97268.1 - 4.2e-16 58.9 0.1 6.1e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAI97269.1 - 0.0005 20.1 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like DDE_3 PF13358.6 OAI97273.1 - 9.2e-15 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAI97273.1 - 3.4e-05 24.4 0.1 0.0001 22.8 0.0 1.8 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAI97273.1 - 0.00051 19.6 0.6 0.0011 18.5 0.6 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAI97273.1 - 0.0066 16.7 0.4 0.012 15.8 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_Tnp_IS630 PF01710.16 OAI97273.1 - 0.021 14.9 0.3 0.036 14.1 0.3 1.3 1 0 0 1 1 1 0 Transposase Toprim_C_rpt PF13368.6 OAI97273.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat UBX PF00789.20 OAI97274.1 - 4.3e-07 30.0 0.0 8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain CRAL_TRIO PF00650.20 OAI97290.1 - 2.9e-13 49.9 0.0 5.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAI97290.1 - 6.1e-13 48.7 1.2 1.2e-12 47.7 1.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DNA_pol_A_exoN PF18305.1 OAI97290.1 - 0.029 14.7 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain CRAL_TRIO PF00650.20 OAI97291.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain HOIP-UBA PF16678.5 OAI97291.1 - 0.036 14.1 0.2 0.047 13.7 0.2 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair NuDC PF16273.5 OAI97295.1 - 0.14 12.7 0.4 0.2 12.2 0.4 1.1 1 0 0 1 1 1 0 Nuclear distribution C domain Pkinase PF00069.25 OAI97298.1 - 8.8e-23 81.0 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97298.1 - 2.1e-11 43.6 0.0 3.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAI97298.1 - 3.8e-08 32.5 0.1 3.8e-08 32.5 0.1 1.8 2 1 0 2 2 2 1 Fungal protein kinase TP2 PF01254.18 OAI97304.1 - 0.0089 16.6 3.6 0.015 15.9 3.6 1.3 1 0 0 1 1 1 1 Nuclear transition protein 2 SIKE PF05769.11 OAI97308.1 - 0.00013 22.0 11.1 0.00034 20.6 4.9 2.5 2 0 0 2 2 2 2 SIKE family YabA PF06156.13 OAI97308.1 - 1 10.0 0.0 1 10.0 0.0 4.3 3 1 1 4 4 4 0 Initiation control protein YabA Nop14 PF04147.12 OAI97308.1 - 1.8 6.7 37.4 1 7.5 34.2 2.0 2 0 0 2 2 2 0 Nop14-like family VIR_N PF15912.5 OAI97308.1 - 2.6 7.6 16.9 5.6 6.5 16.9 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal Melittin PF01372.17 OAI97313.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.0 2 0 0 2 2 2 0 Melittin Spore_III_AF PF09581.10 OAI97313.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4551 PF15087.6 OAI97313.1 - 3.5 6.4 6.3 0.91 8.3 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) Thi4 PF01946.17 OAI97316.1 - 5.3e-16 58.6 0.1 5.8e-08 32.3 0.1 2.1 1 1 1 2 2 2 2 Thi4 family Homeodomain PF00046.29 OAI97324.1 - 7.6e-23 80.1 1.5 4.5e-14 52.0 0.1 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 OAI97324.1 - 3.4e-07 30.1 1.2 0.00029 20.7 0.1 2.5 2 0 0 2 2 2 2 Homeobox KN domain HTH_28 PF13518.6 OAI97324.1 - 0.0057 16.8 0.3 4.6 7.5 0.0 2.9 3 0 0 3 3 3 2 Helix-turn-helix domain 2Fe-2S_thioredx PF01257.19 OAI97324.1 - 0.025 14.4 0.0 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin HTH_Crp_2 PF13545.6 OAI97324.1 - 0.059 13.4 0.0 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain Sigma70_ner PF04546.13 OAI97324.1 - 0.31 10.9 6.6 4.7 7.0 3.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Inhibitor_I53 PF11714.8 OAI97324.1 - 5.7 7.2 8.6 0.66 10.2 2.6 2.2 2 0 0 2 2 2 0 Thrombin inhibitor Madanin DSPc PF00782.20 OAI97328.1 - 1.8e-16 60.2 0.0 1.6e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAI97328.1 - 0.063 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Menin PF05053.13 OAI97330.1 - 0.23 9.8 7.9 0.35 9.2 7.9 1.2 1 0 0 1 1 1 0 Menin DUF3245 PF11595.8 OAI97330.1 - 3.7 8.0 7.7 21 5.6 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) rve PF00665.26 OAI97346.1 - 1.4e-12 47.8 0.0 2.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAI97346.1 - 8e-11 41.8 0.0 1.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HTH_15 PF12324.8 OAI97346.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase GRP PF07172.11 OAI97346.1 - 0.29 11.8 7.6 0.58 10.9 7.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family zf-CCHC PF00098.23 OAI97346.1 - 1.4 9.1 10.9 0.93 9.7 8.7 1.9 2 0 0 2 2 2 0 Zinc knuckle MULE PF10551.9 OAI97351.1 - 7e-16 58.4 0.1 1.8e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAI97351.1 - 1.5e-07 30.7 0.0 2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family PGM1_C PF18105.1 OAI97356.1 - 0.051 13.1 0.0 0.2 11.2 0.0 2.0 3 0 0 3 3 3 0 PGM1 C-terminal domain Ribosomal_S13 PF00416.22 OAI97358.1 - 4.9e-21 75.5 0.0 3.2e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 FbpA PF05833.11 OAI97358.1 - 0.0029 16.4 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) CX9C PF16860.5 OAI97359.1 - 0.00036 20.5 3.3 0.022 14.8 3.5 2.1 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 OAI97359.1 - 0.023 14.9 0.6 0.043 14.1 0.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 OAI97359.1 - 0.089 12.8 1.4 0.46 10.5 1.9 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like IPPT PF01715.17 OAI97362.1 - 4.3e-37 128.1 1.1 3.2e-35 122.0 0.1 2.9 2 1 0 2 2 2 1 IPP transferase DctP PF03480.13 OAI97362.1 - 0.16 11.3 0.4 0.36 10.1 0.4 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Mito_carr PF00153.27 OAI97367.1 - 0.0063 16.4 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein AMMECR1 PF01871.17 OAI97370.1 - 4.3e-47 159.8 0.0 5.3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Cullin_binding PF03556.15 OAI97375.1 - 4.1e-32 111.1 0.0 8.1e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 OAI97375.1 - 2.3e-07 30.5 0.1 4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Herpes_UL21 PF03252.13 OAI97375.1 - 0.054 12.2 0.3 0.09 11.5 0.1 1.4 2 0 0 2 2 2 0 Herpesvirus UL21 Peptidase_C48 PF02902.19 OAI97380.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.4 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain Cutinase PF01083.22 OAI97383.1 - 9.6e-19 68.0 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 OAI97383.1 - 0.017 14.8 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.11 OAI97383.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 2 0 0 2 2 2 0 PE-PPE domain Hydrolase_4 PF12146.8 OAI97383.1 - 0.71 9.1 5.2 4.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Serine aminopeptidase, S33 CLTH PF10607.9 OAI97386.1 - 1.1e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 OAI97386.1 - 4e-08 33.2 0.3 8.4e-08 32.1 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAI97386.1 - 4.7e-05 23.3 0.6 9.4e-05 22.3 0.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAI97386.1 - 0.00082 19.5 0.4 0.0019 18.3 0.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAI97386.1 - 0.0014 18.9 1.3 0.0033 17.7 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAI97386.1 - 0.002 18.0 0.6 0.0038 17.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAI97386.1 - 0.0025 17.6 1.3 0.0047 16.8 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAI97386.1 - 0.0027 17.5 1.8 0.0056 16.5 1.1 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 OAI97386.1 - 0.0041 16.9 0.9 0.0087 15.9 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LisH PF08513.11 OAI97386.1 - 0.076 13.0 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 LisH LMP PF04778.12 OAI97386.1 - 0.14 12.0 1.1 5.3 6.9 1.8 2.1 2 0 0 2 2 2 0 LMP repeated region NDC10_II PF16787.5 OAI97390.1 - 0.0048 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CbiG_C PF01890.16 OAI97390.1 - 0.039 14.5 0.5 0.15 12.6 0.9 1.8 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Phage_int_SAM_4 PF13495.6 OAI97390.1 - 0.074 13.5 0.2 0.16 12.5 0.0 1.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RVT_3 PF13456.6 OAI97393.1 - 0.041 13.7 0.1 0.058 13.2 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like DDE_Tnp_1 PF01609.21 OAI97397.1 - 7.8e-20 71.4 0.9 1.5e-19 70.5 0.9 1.5 1 1 0 1 1 1 1 Transposase DDE domain MREG PF15812.5 OAI97399.1 - 0.18 12.1 0.8 0.34 11.2 0.8 1.4 1 0 0 1 1 1 0 Melanoregulin DUF1178 PF06676.11 OAI97399.1 - 4 7.8 6.6 0.95 9.8 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) OrfB_Zn_ribbon PF07282.11 OAI97404.1 - 1.2e-12 47.6 0.1 2.4e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain HTH_OrfB_IS605 PF12323.8 OAI97404.1 - 9.3e-10 37.8 0.3 2.4e-09 36.6 0.3 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain OrfB_IS605 PF01385.19 OAI97404.1 - 6e-05 23.2 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 Probable transposase Peptidase_S10 PF00450.22 OAI97417.1 - 1.6e-28 100.3 0.0 7.5e-23 81.6 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase G10 PF01125.17 OAI97420.1 - 4.6e-54 182.2 8.9 5.3e-54 182.0 8.9 1.0 1 0 0 1 1 1 1 G10 protein Syntaxin-6_N PF09177.11 OAI97421.1 - 2.1e-16 60.3 1.0 2.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF4407 PF14362.6 OAI97421.1 - 0.00028 20.4 0.0 0.00049 19.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) FliJ PF02050.16 OAI97421.1 - 0.00034 20.8 2.7 0.0086 16.3 0.5 2.5 2 1 1 3 3 3 1 Flagellar FliJ protein DUF2046 PF09755.9 OAI97421.1 - 0.00081 18.7 2.4 0.38 9.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Use1 PF09753.9 OAI97421.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 HisKA_3 PF07730.13 OAI97421.1 - 0.011 16.2 4.1 0.47 11.0 0.1 2.4 2 0 0 2 2 2 0 Histidine kinase FlaC_arch PF05377.11 OAI97421.1 - 0.022 15.2 0.3 12 6.4 0.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ARTD15_N PF18084.1 OAI97421.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ARTD15 N-terminal domain SNARE PF05739.19 OAI97421.1 - 0.11 12.5 8.1 0.054 13.5 4.5 2.3 2 1 0 2 2 2 0 SNARE domain DUF1664 PF07889.12 OAI97421.1 - 0.14 12.2 0.3 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 OAI97421.1 - 0.3 11.6 1.2 5.5 7.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 ZapB PF06005.12 OAI97421.1 - 1.6 9.3 7.5 1.7 9.2 0.3 3.0 3 1 1 4 4 4 0 Cell division protein ZapB ATG16 PF08614.11 OAI97421.1 - 3.8 7.7 8.9 24 5.1 0.1 2.3 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAI97421.1 - 5.1 7.2 8.8 8.6 6.4 2.6 3.0 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein Cdd1 PF11731.8 OAI97424.1 - 0.13 12.5 0.0 2.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Pathogenicity locus p450 PF00067.22 OAI97428.1 - 3.2e-13 49.2 0.0 4.4e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spt5_N PF11942.8 OAI97431.1 - 1.2e-18 67.9 11.5 1.2e-18 67.9 11.5 3.9 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 OAI97431.1 - 1.8e-15 56.6 0.0 4.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OAI97431.1 - 1.4e-08 34.3 7.7 5.6e-06 26.1 0.4 2.7 2 0 0 2 2 2 2 KOW motif Chordopox_G2 PF05796.12 OAI97431.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 Hexapep PF00132.24 OAI97431.1 - 0.16 11.8 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial transferase hexapeptide (six repeats) FAD_binding_1 PF00667.20 OAI97433.1 - 7.9e-29 100.8 0.0 1.2e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAI97433.1 - 1.4e-24 86.9 0.0 3.2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAI97433.1 - 5.4e-07 30.2 0.0 1.8e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 OAI97433.1 - 0.0049 17.1 0.0 0.0098 16.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Phage_int_SAM_1 PF02899.17 OAI97437.1 - 0.12 12.6 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PRA-PH PF01503.17 OAI97440.1 - 6.8e-14 52.1 0.6 1.4e-13 51.1 0.6 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase NOG1_N PF17835.1 OAI97440.1 - 1.3e-05 25.2 0.2 3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain MazG PF03819.17 OAI97440.1 - 0.00082 19.5 0.1 0.0015 18.6 0.1 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 OAI97440.1 - 0.23 11.8 0.0 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 MazG-like family Vps5 PF09325.10 OAI97447.1 - 5.9e-05 22.7 2.1 0.0041 16.7 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like IKBKB_SDD PF18397.1 OAI97447.1 - 0.022 14.1 0.2 0.039 13.3 0.2 1.3 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain FAM92 PF06730.11 OAI97447.1 - 0.069 12.6 0.6 0.12 11.7 0.6 1.4 1 0 0 1 1 1 0 FAM92 protein SMI1_KNR4 PF09346.10 OAI97455.1 - 1e-20 74.5 0.0 1.9e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) NPV_P10 PF05531.12 OAI97460.1 - 1.3 9.5 0.0 1.3 9.5 0.0 4.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Asp PF00026.23 OAI97479.1 - 8.9e-22 77.9 6.8 4.7e-21 75.5 6.8 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAI97479.1 - 3.8e-08 33.8 2.7 0.00011 22.5 0.2 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAI97479.1 - 0.019 15.6 1.0 0.052 14.2 0.3 1.9 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 OAI97479.1 - 0.029 14.9 0.3 0.079 13.5 0.1 1.8 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.23 OAI97480.1 - 7.1e-35 120.9 0.1 9e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 OAI97480.1 - 0.00016 21.5 0.0 0.00077 19.3 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Exo_endo_phos_2 PF14529.6 OAI97486.1 - 4.5e-18 65.2 0.6 1.5e-17 63.6 0.2 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAI97486.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dimer_Tnp_hAT PF05699.14 OAI97494.1 - 9.7e-21 73.4 0.0 2.4e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PMT PF02366.18 OAI97502.1 - 7e-09 35.6 1.3 0.00017 21.3 0.1 2.1 1 1 1 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase RVT_2 PF07727.14 OAI97508.1 - 1.4e-14 54.3 0.0 2.1e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI97508.1 - 0.0016 18.3 0.7 0.0048 16.7 0.7 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like RVT_2 PF07727.14 OAI97509.1 - 1.4e-23 83.8 0.0 2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELFV_dehydrog PF00208.21 OAI97524.1 - 7.8e-24 84.7 0.0 9.4e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Torus PF16131.5 OAI97530.1 - 3.6e-37 127.4 0.5 1.1e-36 125.8 0.5 1.9 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 OAI97530.1 - 1.6e-08 34.3 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 OAI97530.1 - 0.00011 22.1 1.1 0.00019 21.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAI97530.1 - 0.00015 21.6 1.7 0.00028 20.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAI97530.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Malectin_like PF12819.7 OAI97530.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Malectin-like domain zf-CCCH_4 PF18044.1 OAI97530.1 - 0.31 10.9 2.6 0.54 10.1 2.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger Strabismus PF06638.11 OAI97530.1 - 8.7 4.9 6.1 15 4.1 6.1 1.2 1 0 0 1 1 1 0 Strabismus protein Prenyltrans PF00432.21 OAI97531.1 - 1.9e-09 37.1 0.0 2.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat TRAPPC9-Trs120 PF08626.11 OAI97536.1 - 0.15 9.4 1.0 0.16 9.3 1.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Herpes_BLLF1 PF05109.13 OAI97537.1 - 0.035 12.1 7.4 0.042 11.8 7.4 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) UPF0058 PF01893.16 OAI97541.1 - 0.22 11.8 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 RVT_2 PF07727.14 OAI97548.1 - 1e-67 228.3 0.0 1.4e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAI97563.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CN_hydrolase PF00795.22 OAI97577.1 - 9.2e-19 67.8 0.0 3.5e-14 52.8 0.0 3.0 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase Med26 PF08711.11 OAI97588.1 - 3e-07 30.3 0.1 4.4e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2884 PF11101.8 OAI97588.1 - 0.08 12.4 1.2 0.1 12.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Ras PF00071.22 OAI97589.1 - 2.5e-50 170.2 0.2 3.5e-50 169.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAI97589.1 - 1.4e-28 99.5 0.0 2.7e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAI97589.1 - 6.6e-11 42.0 0.0 2.2e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAI97589.1 - 1.1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAI97589.1 - 0.00075 19.1 0.1 0.0027 17.2 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAI97589.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 OAI97589.1 - 0.018 15.1 0.4 0.041 13.9 0.4 1.9 1 1 0 1 1 1 0 Dynamin family DUF89 PF01937.19 OAI97589.1 - 0.029 13.3 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 DDE_Tnp_4 PF13359.6 OAI97594.1 - 8.8e-08 32.0 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Proteasome PF00227.26 OAI97598.1 - 5.1e-23 81.5 0.0 8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit CAP_N PF01213.19 OAI97603.1 - 0.86 9.0 0.0 0.86 9.0 0.0 2.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal zf-C3HC4_3 PF13920.6 OAI97606.1 - 0.029 14.2 1.6 0.048 13.5 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 OAI97608.1 - 3.8e-09 36.3 0.7 0.046 13.6 0.0 4.0 4 0 0 4 4 4 3 Mitochondrial carrier protein Varsurf_PPLC PF03490.13 OAI97616.1 - 4.3e-05 23.4 0.1 0.0001 22.1 0.1 1.7 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C DUF3662 PF12401.8 OAI97616.1 - 0.094 13.1 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) RVT_1 PF00078.27 OAI97620.1 - 1.1e-13 51.2 0.0 2.4e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAI97641.1 - 1.4e-12 47.5 0.1 2.4e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAI97641.1 - 0.038 14.1 11.1 0.13 12.4 1.2 2.7 2 1 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 OAI97641.1 - 0.12 12.2 2.8 13 5.6 1.1 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 OAI97641.1 - 6.1 6.7 5.4 23 4.8 0.7 2.7 2 0 0 2 2 2 0 Zinc knuckle PIN_4 PF13638.6 OAI97644.1 - 8.6e-22 77.8 0.0 3.2e-21 76.0 0.0 2.0 1 1 0 1 1 1 1 PIN domain Nucleo_P87 PF07267.11 OAI97656.1 - 0.013 14.4 5.5 0.014 14.3 5.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2457 PF10446.9 OAI97656.1 - 0.065 12.4 10.0 0.068 12.3 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4746 PF15928.5 OAI97656.1 - 0.11 12.0 3.1 0.12 11.7 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SGT1 PF07093.11 OAI97656.1 - 0.13 10.6 4.3 0.13 10.7 4.3 1.0 1 0 0 1 1 1 0 SGT1 protein RXT2_N PF08595.11 OAI97656.1 - 0.15 12.1 5.5 0.16 12.0 5.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 OAI97656.1 - 0.18 11.5 9.8 0.21 11.4 9.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 OAI97656.1 - 0.26 10.5 10.1 0.29 10.4 10.1 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 OAI97656.1 - 0.33 11.2 12.6 0.36 11.0 12.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 OAI97656.1 - 0.42 10.3 12.7 0.56 9.9 12.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 OAI97656.1 - 0.49 9.9 12.3 0.58 9.7 12.3 1.1 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 OAI97656.1 - 0.65 9.6 6.0 0.88 9.2 6.0 1.3 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 OAI97656.1 - 1.1 8.8 7.2 1.6 8.3 7.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4637 PF15470.6 OAI97656.1 - 1.3 8.8 6.1 1.7 8.4 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 OAI97656.1 - 6.4 4.9 11.7 7.5 4.7 11.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAI97656.1 - 9.1 4.7 7.5 9.7 4.6 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pes-10 PF07149.11 OAI97656.1 - 9.2 5.2 8.7 10 5.0 8.7 1.1 1 0 0 1 1 1 0 Pes-10 AAA PF00004.29 OAI97657.1 - 8.8e-26 90.9 0.0 1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAI97657.1 - 6.7e-07 29.9 0.1 0.00065 20.1 0.1 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAI97657.1 - 3.7e-06 27.3 0.1 0.0012 19.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAI97657.1 - 6e-06 26.1 0.7 2.6e-05 24.0 0.7 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAI97657.1 - 7.6e-05 22.7 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAI97657.1 - 0.00015 21.4 0.2 0.00032 20.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAI97657.1 - 0.0042 17.3 0.0 0.005 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAI97657.1 - 0.007 15.6 0.0 0.0073 15.5 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 OAI97657.1 - 0.021 15.4 0.0 0.032 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAI97657.1 - 0.022 15.1 0.8 0.15 12.4 0.1 2.3 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 OAI97657.1 - 0.023 14.7 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAI97657.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.3 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 OAI97657.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAI97657.1 - 0.082 12.4 0.2 0.19 11.2 0.1 1.7 1 1 1 2 2 2 0 PhoH-like protein AAA_35 PF14516.6 OAI97657.1 - 0.084 11.7 0.0 0.33 9.8 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.6 OAI97657.1 - 0.085 13.1 0.1 0.12 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 OAI97657.1 - 0.087 12.6 0.1 0.17 11.6 0.1 1.6 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 OAI97657.1 - 0.092 11.9 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAI97657.1 - 0.12 12.3 0.0 0.54 10.1 0.0 1.9 1 1 1 2 2 2 0 NTPase KTI12 PF08433.10 OAI97657.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MRP-L47 PF06984.13 OAI97661.1 - 5.4e-14 52.1 0.5 1.1e-13 51.1 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 OAI97661.1 - 0.01 15.8 1.5 0.051 13.5 1.5 2.1 1 1 0 1 1 1 0 Ribosomal L29 protein DASH_Spc19 PF08287.11 OAI97662.1 - 1.8e-11 44.2 1.8 1.8e-11 44.2 1.8 2.0 2 0 0 2 2 2 1 Spc19 DUF812 PF05667.11 OAI97662.1 - 0.0077 15.2 4.2 0.0094 14.9 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GCN5L1 PF06320.13 OAI97662.1 - 0.0085 16.2 5.7 0.009 16.2 0.1 2.1 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) Exonuc_VII_L PF02601.15 OAI97662.1 - 0.11 12.0 4.9 0.14 11.7 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 OAI97662.1 - 0.2 10.9 7.7 0.27 10.5 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 OAI97662.1 - 0.29 11.3 6.3 0.99 9.5 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) STAG PF08514.11 OAI97662.1 - 0.71 9.8 5.2 4.6 7.2 0.9 2.1 2 0 0 2 2 2 0 STAG domain OEP PF02321.18 OAI97662.1 - 2.4 7.9 11.9 2.2 8.1 3.5 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Y_phosphatase2 PF03162.13 OAI97666.1 - 2.8e-22 79.0 0.0 3.8e-13 49.4 0.0 2.5 3 0 0 3 3 3 2 Tyrosine phosphatase family Ribosomal_60s PF00428.19 OAI97666.1 - 0.012 16.2 9.5 0.028 15.0 9.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RXT2_N PF08595.11 OAI97666.1 - 0.17 11.9 6.4 0.29 11.2 4.3 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Myc_N PF01056.18 OAI97666.1 - 0.48 10.3 5.3 0.083 12.8 0.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region BSP_II PF05432.11 OAI97666.1 - 0.64 9.7 15.0 25 4.4 13.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4746 PF15928.5 OAI97666.1 - 1.5 8.2 7.7 2.1 7.7 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RPN2_C PF18004.1 OAI97666.1 - 1.7 8.5 5.8 1.8 8.5 1.2 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4820 PF16091.5 OAI97666.1 - 5.9 6.2 5.8 4.6 6.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sporozoite_P67 PF05642.11 OAI97666.1 - 7.8 4.4 7.8 0.59 8.1 1.5 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 OAI97666.1 - 8.9 5.1 9.4 12 4.7 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RT_RNaseH PF17917.1 OAI97667.1 - 5.7e-13 49.1 0.0 7.3e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI97667.1 - 1.4e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI97670.1 - 2.2e-21 75.8 0.0 6.2e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97670.1 - 2.5e-16 59.8 0.0 9.8e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI97670.1 - 1.6e-14 53.8 0.1 3.2e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI97670.1 - 4.5e-12 46.2 0.0 1.1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain p450 PF00067.22 OAI97674.1 - 9.7e-20 70.7 0.0 3.2e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.25 OAI97679.1 - 3.9e-14 52.9 0.0 4.6e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAI97679.1 - 4e-08 33.3 0.1 4.5e-08 33.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAI97679.1 - 9.6e-07 29.1 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAI97679.1 - 0.00049 20.0 0.0 0.00071 19.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAI97679.1 - 0.0048 17.0 0.1 0.0071 16.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAI97679.1 - 0.094 12.2 0.2 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Putative acetyl-transferase PIF1 PF05970.14 OAI97683.1 - 0.0071 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Torsin PF06309.11 OAI97683.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin Integrase_H2C2 PF17921.1 OAI97692.1 - 8.6e-11 41.8 1.3 1.9e-10 40.7 1.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI97692.1 - 4.6e-10 39.7 0.0 1.7e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF2268 PF10026.9 OAI97692.1 - 0.013 15.0 0.6 0.026 14.1 0.6 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) rve_3 PF13683.6 OAI97692.1 - 0.019 14.7 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Myb_DNA-bind_4 PF13837.6 OAI97695.1 - 0.015 15.7 0.0 0.034 14.5 0.0 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Sterol_MT_C PF08498.10 OAI97701.1 - 1.6e-28 98.8 0.2 2.2e-28 98.4 0.2 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal HRM PF02793.22 OAI97701.1 - 0.023 15.0 1.0 0.035 14.4 1.0 1.2 1 0 0 1 1 1 0 Hormone receptor domain GramPos_pilinD1 PF16555.5 OAI97706.1 - 0.031 14.4 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Gram-positive pilin subunit D1, N-terminal domain RRM_1 PF00076.22 OAI97708.1 - 0.032 14.0 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L29 PF00831.23 OAI97709.1 - 1.1e-18 66.9 3.5 1.1e-18 66.9 3.5 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein FUSC PF04632.12 OAI97712.1 - 0.36 9.3 1.4 0.45 9.0 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SurE PF01975.17 OAI97718.1 - 7.2e-39 133.6 0.0 1.3e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATE_C PF04377.15 OAI97723.1 - 4.9e-31 108.1 0.1 7.2e-31 107.6 0.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Glyco_transf_8 PF01501.20 OAI97724.1 - 1.6e-11 44.3 0.0 3.4e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAI97724.1 - 0.0037 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative p450 PF00067.22 OAI97730.1 - 7.8e-60 202.9 0.6 1.5e-49 169.0 0.6 3.8 1 1 1 2 2 2 2 Cytochrome P450 TM_helix PF05552.12 OAI97730.1 - 6.2 6.9 7.2 14 5.7 7.2 1.6 1 0 0 1 1 1 0 Conserved TM helix DUF3611 PF12263.8 OAI97734.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Cadherin_4 PF17803.1 OAI97751.1 - 0.16 12.6 3.8 0.35 11.5 3.8 1.6 1 0 0 1 1 1 0 Bacterial cadherin-like domain SLC12 PF03522.15 OAI97755.1 - 0.052 12.6 3.0 0.071 12.1 3.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RRP36 PF06102.12 OAI97755.1 - 0.22 11.5 8.7 0.37 10.7 8.7 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 CTI PF06934.11 OAI97755.1 - 0.22 10.0 2.7 0.3 9.6 2.7 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DctP PF03480.13 OAI97755.1 - 0.37 10.1 5.2 0.64 9.3 5.2 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF4192 PF13830.6 OAI97755.1 - 1.1 9.2 10.3 2 8.4 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TPR_10 PF13374.6 OAI97760.1 - 9.6e-10 38.0 8.0 0.00047 19.9 0.0 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAI97760.1 - 4.7e-07 30.0 9.8 0.0097 16.2 0.3 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAI97760.1 - 0.0033 17.4 10.6 11 6.4 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAI97760.1 - 0.081 13.8 12.0 35 5.6 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat SLT_2 PF13406.6 OAI97760.1 - 0.16 11.2 2.1 0.52 9.5 0.0 2.6 3 0 0 3 3 3 0 Transglycosylase SLT domain TPR_6 PF13174.6 OAI97760.1 - 0.89 10.3 4.6 20 6.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 OAI97765.1 - 1.5e-23 83.6 0.2 2e-23 83.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI97765.1 - 3.9e-14 52.6 0.2 5.5e-14 52.1 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 OAI97765.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPL5 PF18168.1 OAI97765.1 - 0.4 9.9 5.3 0.66 9.2 5.3 1.4 1 0 0 1 1 1 0 Prim-pol family 5 OrgA_MxiK PF09482.10 OAI97770.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) gag_pre-integrs PF13976.6 OAI97773.1 - 4e-06 26.6 0.0 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAI97773.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ELP6 PF09807.9 OAI97796.1 - 3e-08 33.4 0.0 4.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 NACHT PF05729.12 OAI97796.1 - 0.0045 16.9 0.1 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain Sde2_N_Ubi PF13019.6 OAI97801.1 - 0.0064 16.3 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Pax2_C PF12403.8 OAI97801.1 - 0.18 11.9 6.3 0.17 12.0 0.3 2.8 3 0 0 3 3 3 0 Paired-box protein 2 C terminal Sua5_yciO_yrdC PF01300.18 OAI97809.1 - 7.9e-47 159.1 0.0 4.2e-45 153.4 0.0 2.5 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 OAI97809.1 - 9.7e-28 97.4 0.0 4.5e-27 95.2 0.0 2.0 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Glyco_hydro_92 PF07971.12 OAI97813.1 - 7.7e-42 143.8 0.0 9.5e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 VWA PF00092.28 OAI97814.1 - 0.028 14.6 0.1 0.032 14.5 0.1 1.0 1 0 0 1 1 1 0 von Willebrand factor type A domain UPF0560 PF10577.9 OAI97818.1 - 7.3 5.0 9.9 11 4.4 9.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Asp_protease_2 PF13650.6 OAI97821.1 - 4.5e-05 24.0 0.0 9.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI97821.1 - 0.00015 22.3 0.0 0.00045 20.7 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI97821.1 - 0.053 13.8 0.0 0.28 11.5 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease RVT_1 PF00078.27 OAI97821.1 - 0.18 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4124 PF13511.6 OAI97822.1 - 1.3 9.4 5.6 2 8.8 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Phage_integrase PF00589.22 OAI97835.1 - 6.3e-05 22.8 0.0 7.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family TPR_10 PF13374.6 OAI97839.1 - 3.5e-17 61.7 23.4 0.0011 18.7 0.4 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAI97839.1 - 5.6e-14 52.2 26.2 2e-05 24.8 1.6 6.3 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAI97839.1 - 5e-05 23.8 18.7 15 6.7 0.2 8.0 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAI97839.1 - 0.00013 21.9 17.0 16 5.9 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat FAT PF02259.23 OAI97839.1 - 0.028 13.6 5.9 2 7.5 1.5 2.7 1 1 0 2 2 2 0 FAT domain MOLO1 PF17175.4 OAI97839.1 - 0.19 11.9 0.1 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 ANAPC5 PF12862.7 OAI97839.1 - 0.53 10.4 11.3 3.4 7.8 1.6 5.4 2 2 3 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_4 PF07721.14 OAI97839.1 - 0.58 11.0 12.6 12 6.9 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 OAI97839.1 - 0.83 9.8 15.8 1.8 8.8 1.4 4.0 2 2 1 4 4 4 0 PEP-utilising enzyme, N-terminal T2SSF PF00482.23 OAI97839.1 - 0.87 9.6 7.7 31 4.6 1.5 3.8 1 1 0 3 3 3 0 Type II secretion system (T2SS), protein F SPOR PF05036.13 OAI97839.1 - 1.5 9.2 5.0 0.91 10.0 0.3 3.0 3 0 0 3 3 3 0 Sporulation related domain BTAD PF03704.17 OAI97839.1 - 2.4 8.6 18.0 1.7 9.1 0.7 5.4 3 2 1 4 4 4 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 OAI97839.1 - 5 7.4 7.9 11 6.3 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-bind_4 PF13837.6 OAI97845.1 - 0.00027 21.3 0.3 0.00079 19.8 0.3 1.9 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain ThiD2 PF17792.1 OAI97845.1 - 2 8.9 9.3 1.2 9.6 5.4 2.3 2 0 0 2 2 2 0 ThiD2 family DUF2058 PF09831.9 OAI97845.1 - 5.2 7.2 9.6 4.1 7.5 7.7 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) RT_RNaseH_2 PF17919.1 OAI97853.1 - 6e-22 77.6 0.0 4.1e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97853.1 - 1.1e-16 61.0 0.0 6.9e-12 45.6 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI97853.1 - 3.6e-16 59.4 0.0 5.8e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAI97853.1 - 4.3e-16 58.8 0.0 9.3e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI97853.1 - 1.2e-11 44.8 0.0 3.6e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAI97853.1 - 0.038 14.2 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF148 PF02520.17 OAI97857.1 - 0.051 13.7 3.5 0.085 13.0 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF148 Presenilin PF01080.17 OAI97858.1 - 2.8 6.6 3.3 2.3 6.9 3.3 1.2 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 OAI97858.1 - 3.5 7.2 24.6 5.7 6.5 24.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 OAI97858.1 - 4.3 7.6 29.0 8 6.8 29.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TLP-20 PF06088.11 OAI97862.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 OAI97862.1 - 4 6.1 6.6 6.1 5.5 6.6 1.2 1 0 0 1 1 1 0 Presenilin FAD_binding_2 PF00890.24 OAI97870.1 - 6.1e-60 203.4 3.8 5.8e-48 164.0 0.1 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAI97870.1 - 2.9e-22 79.7 8.6 2.8e-13 50.2 1.9 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAI97870.1 - 3.7e-21 75.1 7.1 9.9e-10 38.5 0.5 3.2 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 OAI97870.1 - 3.8e-16 59.5 3.9 7e-08 32.2 0.6 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAI97870.1 - 4.6e-13 49.2 1.8 3.7e-06 26.4 0.6 2.4 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 OAI97870.1 - 5.5e-13 48.4 0.7 4.2e-05 22.4 0.1 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.14 OAI97870.1 - 2e-12 47.0 2.1 1.9e-07 30.6 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAI97870.1 - 8.2e-11 41.7 0.2 0.0032 16.8 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAI97870.1 - 1.3e-10 40.9 4.2 0.0013 17.9 0.3 3.1 3 0 0 3 3 3 3 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAI97870.1 - 1.4e-10 41.1 0.3 0.00079 18.8 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 OAI97870.1 - 4.7e-10 39.1 0.2 0.00021 20.7 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAI97870.1 - 1.4e-08 35.1 2.2 0.0056 17.2 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAI97870.1 - 1.5e-08 34.1 1.1 0.0014 17.9 0.1 2.5 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 OAI97870.1 - 1.5e-06 28.3 0.5 0.43 10.6 0.1 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAI97870.1 - 7.2e-06 26.4 0.0 0.054 13.9 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding GDI PF00996.18 OAI97870.1 - 9.1e-06 24.4 0.2 0.044 12.3 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor TrkA_N PF02254.18 OAI97870.1 - 2.3e-05 24.6 0.2 0.25 11.6 0.0 2.8 3 0 0 3 3 3 2 TrkA-N domain Lycopene_cycl PF05834.12 OAI97870.1 - 2.3e-05 23.6 0.3 0.075 12.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein 3HCDH_N PF02737.18 OAI97870.1 - 0.00062 19.7 0.3 0.37 10.7 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1188 PF06690.11 OAI97870.1 - 0.003 17.1 0.0 0.84 9.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) YjeF_N PF03853.15 OAI97870.1 - 0.013 15.4 0.1 4.9 7.0 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus MCRA PF06100.11 OAI97870.1 - 0.015 14.1 0.5 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 MCRA family UDPG_MGDP_dh_N PF03721.14 OAI97870.1 - 0.023 14.3 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Calici_PP_N PF08405.11 OAI97870.1 - 0.024 13.4 0.0 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Viral polyprotein N-terminal adh_short PF00106.25 OAI97870.1 - 0.027 13.9 0.2 3.6 7.0 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Trp_halogenase PF04820.14 OAI97870.1 - 0.066 12.1 0.4 2.3 7.0 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase RVT_1 PF00078.27 OAI97874.1 - 0.16 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAI97877.1 - 6.1e-16 58.3 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI97877.1 - 1.4e-12 47.8 0.0 2.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAI97877.1 - 1.3e-11 44.7 0.0 5.7e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI97877.1 - 1.1e-06 28.6 0.0 6.8e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAI97877.1 - 0.037 14.3 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger DUF2457 PF10446.9 OAI97880.1 - 0.56 9.3 21.0 0.79 8.8 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 OAI97880.1 - 3.8 5.7 7.2 4.3 5.5 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAI97880.1 - 5 5.1 22.2 6.6 4.7 22.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Complex1_LYR PF05347.15 OAI97881.1 - 7.5e-10 38.7 5.3 1.4e-09 37.9 5.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAI97881.1 - 0.00029 21.5 0.5 0.00046 20.9 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DUF1768 PF08719.11 OAI97890.1 - 1.7e-18 67.4 0.1 1.9e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sec61_beta PF03911.16 OAI97894.1 - 4.5e-17 61.8 0.7 6e-17 61.4 0.7 1.2 1 0 0 1 1 1 1 Sec61beta family DUF2316 PF10078.9 OAI97896.1 - 0.078 13.2 0.0 0.18 12.1 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Raftlin PF15250.6 OAI97902.1 - 4.3 6.0 12.0 7.5 5.2 12.0 1.4 1 0 0 1 1 1 0 Raftlin PBP1_TM PF14812.6 OAI97905.1 - 0.011 16.1 23.8 0.016 15.5 5.7 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal pP_pnuc_2 PF18166.1 OAI97905.1 - 0.16 12.1 1.9 0.26 11.4 1.9 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease G_path_suppress PF15991.5 OAI97905.1 - 0.35 11.0 16.7 0.51 10.4 16.7 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor Myc_N PF01056.18 OAI97905.1 - 1.9 8.3 16.8 0.089 12.7 8.9 2.1 1 1 1 2 2 2 0 Myc amino-terminal region RAP1 PF07218.11 OAI97905.1 - 3.5 5.8 10.0 4.9 5.3 10.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TipE PF16972.5 OAI97905.1 - 6.1 5.9 13.0 2.2 7.4 9.8 1.7 2 0 0 2 2 2 0 Na+ channel auxiliary subunit TipE Sigma70_ner PF04546.13 OAI97905.1 - 10 6.0 12.2 2.5 7.9 5.2 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region CM_2 PF01817.21 OAI97906.1 - 0.00014 22.1 0.0 0.055 13.8 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II Period_C PF12114.8 OAI97912.1 - 6.7 6.2 8.7 8.7 5.9 8.7 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MULE PF10551.9 OAI97918.1 - 4e-20 72.0 0.0 8.7e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAI97918.1 - 2.7e-09 36.4 0.0 4.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 OAI97918.1 - 3.1e-07 29.9 0.1 8.4e-07 28.5 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 OAI97918.1 - 0.041 13.6 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Transposase zf-CCHC PF00098.23 OAI97918.1 - 8.2 6.7 8.6 2.1 8.6 4.7 2.1 2 0 0 2 2 2 0 Zinc knuckle Pantoate_transf PF02548.15 OAI97934.1 - 7.7e-89 297.5 1.9 1.8e-84 283.2 0.5 2.2 2 0 0 2 2 2 2 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 OAI97934.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.4 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase ORC6 PF05460.13 OAI97935.1 - 7.3 5.8 7.8 0.35 10.1 1.8 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RRM_1 PF00076.22 OAI97944.1 - 1.2e-79 262.0 1.6 6.7e-19 67.5 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAI97944.1 - 2.6e-26 91.6 0.5 3.9e-25 87.8 0.2 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 OAI97944.1 - 7.5e-09 35.2 0.6 0.33 10.5 0.0 4.2 2 1 2 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAI97944.1 - 2.3e-07 30.7 1.1 0.11 12.5 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAI97944.1 - 0.00011 22.3 0.2 9.2 6.5 0.0 4.9 3 2 1 4 4 4 2 RNA recognition motif YflT PF11181.8 OAI97944.1 - 0.0053 17.3 0.8 0.72 10.4 0.3 2.8 2 0 0 2 2 2 1 Heat induced stress protein YflT DUF4523 PF15023.6 OAI97944.1 - 0.034 14.0 0.0 3.8 7.3 0.0 3.4 2 2 1 4 4 4 0 Protein of unknown function (DUF4523) Nefa_Nip30_N PF10187.9 OAI97944.1 - 0.036 14.4 1.3 0.036 14.4 1.3 3.6 4 0 0 4 4 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 YL1 PF05764.13 OAI97954.1 - 0.03 14.4 15.1 0.036 14.2 15.1 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 OAI97954.1 - 0.26 9.8 20.3 0.35 9.4 20.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 OAI97954.1 - 1.4 7.1 10.5 1.6 6.9 10.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 OAI97954.1 - 4.9 5.6 5.3 5.1 5.5 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Abhydrolase_6 PF12697.7 OAI97963.1 - 1.1e-05 26.2 1.5 1.8e-05 25.5 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 OAI97963.1 - 0.048 13.5 0.2 0.12 12.2 0.1 1.5 1 1 1 2 2 2 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 OAI97963.1 - 0.16 11.7 0.2 17 5.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RVT_1 PF00078.27 OAI97966.1 - 2.1e-22 79.7 0.0 3.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI97966.1 - 8e-16 57.9 0.0 2.1e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI97966.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase dUTPase PF00692.19 OAI97966.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 dUTPase HSP70 PF00012.20 OAI97970.1 - 2.7e-17 62.2 0.0 1.3e-16 59.9 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein WD40 PF00400.32 OAI97974.1 - 1.9e-16 60.1 8.8 1e-05 26.1 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI97974.1 - 1.4e-14 54.1 4.8 9.7e-05 22.6 0.0 4.1 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAI97974.1 - 1.9e-05 23.8 0.3 0.00035 19.6 0.2 2.7 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 OAI97974.1 - 0.0023 17.8 0.4 0.073 13.0 0.4 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 OAI97974.1 - 0.0087 14.1 0.5 0.27 9.2 0.3 2.1 2 0 0 2 2 2 2 IKI3 family Tubulin PF00091.25 OAI97985.1 - 5.5e-63 212.7 0.0 8.6e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAI97985.1 - 2.1e-36 124.9 0.0 3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAI97985.1 - 0.00032 21.0 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAI97985.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAI97985.1 - 0.0037 16.5 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin like ART PF01129.18 OAI97985.1 - 0.076 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase Ribonuclease_3 PF00636.26 OAI97998.1 - 3.8e-15 56.4 0.1 2.1e-14 54.0 0.0 2.4 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAI97998.1 - 0.00018 21.7 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease-III-like Presenilin PF01080.17 OAI97998.1 - 1.3 7.7 7.7 0.3 9.8 3.4 1.9 2 0 0 2 2 2 0 Presenilin RVT_1 PF00078.27 OAI98007.1 - 6.5e-18 65.1 0.0 9.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAI98007.1 - 8.4e-05 23.1 0.1 0.00021 21.9 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI98007.1 - 0.0039 17.7 0.1 0.013 16.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAI98007.1 - 0.0067 16.7 0.0 0.045 14.1 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease DUF4218 PF13960.6 OAI98014.1 - 0.014 15.0 0.0 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) Pkinase PF00069.25 OAI98023.1 - 1.7e-38 132.5 0.0 5.5e-38 130.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI98023.1 - 8.1e-23 81.0 0.0 2.2e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase BST2 PF16716.5 OAI98023.1 - 0.017 15.7 8.7 0.017 15.7 8.7 5.2 1 1 4 5 5 5 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 OAI98023.1 - 0.033 14.6 0.6 0.033 14.6 0.6 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Tropomyosin PF00261.20 OAI98023.1 - 0.08 12.3 59.6 0.19 11.1 51.0 3.9 1 1 1 2 2 2 0 Tropomyosin GAS PF13851.6 OAI98023.1 - 0.1 12.0 51.9 0.016 14.6 11.9 4.6 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF2935 PF11155.8 OAI98023.1 - 0.12 12.7 10.2 1.4 9.3 2.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) RIO1 PF01163.22 OAI98023.1 - 0.27 10.8 2.4 0.43 10.1 0.0 2.5 2 1 1 3 3 3 0 RIO1 family APH PF01636.23 OAI98023.1 - 0.3 11.0 0.1 0.3 11.0 0.1 3.4 2 2 1 3 3 2 0 Phosphotransferase enzyme family Tropomyosin_1 PF12718.7 OAI98023.1 - 0.63 10.2 56.2 0.12 12.5 22.1 3.7 2 1 1 3 3 3 0 Tropomyosin like Cep57_CLD PF14073.6 OAI98023.1 - 0.75 9.8 55.7 0.12 12.4 17.8 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of Cep57 HMMR_N PF15905.5 OAI98023.1 - 2.6 7.4 46.5 0.75 9.2 19.8 2.2 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 OAI98023.1 - 3.9 6.3 58.4 0.76 8.6 16.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Got1 PF04178.12 OAI98027.1 - 5.6e-18 65.4 15.6 7e-18 65.1 15.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Thioredoxin PF00085.20 OAI98028.1 - 1.8e-30 105.0 0.0 2.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAI98028.1 - 1.1e-07 32.3 0.1 2.3e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 OAI98028.1 - 8e-07 28.9 0.0 9.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAI98028.1 - 2.3e-06 27.9 0.0 5.6e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAI98028.1 - 3.1e-06 26.8 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 OAI98028.1 - 8.6e-06 25.7 0.0 9.9e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 OAI98028.1 - 9.7e-06 25.4 0.0 2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAI98028.1 - 6.1e-05 22.9 0.0 7.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 OAI98028.1 - 0.0018 18.4 0.0 0.0031 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 OAI98028.1 - 0.0067 16.6 0.1 0.0096 16.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.16 OAI98028.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_3 PF13192.6 OAI98028.1 - 0.075 13.1 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_5 PF13743.6 OAI98028.1 - 0.11 12.2 0.1 2.7 7.6 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DUF2847 PF11009.8 OAI98028.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) adh_short PF00106.25 OAI98041.1 - 6.1e-23 81.3 0.0 6.8e-21 74.6 0.0 2.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAI98041.1 - 6.6e-16 58.6 0.0 7.2e-14 51.9 0.0 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI98041.1 - 0.0036 16.8 0.0 0.0053 16.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAI98041.1 - 0.012 15.0 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAI98042.1 - 3e-23 82.3 0.0 5.4e-15 55.4 0.0 2.4 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAI98042.1 - 2.2e-16 60.1 0.0 1.6e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAI98042.1 - 3.5e-06 26.7 0.0 7.1e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAI98042.1 - 0.00036 20.5 0.0 0.00062 19.7 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAI98042.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PALP PF00291.25 OAI98046.1 - 1.6e-60 205.0 1.1 1.6e-60 205.0 1.1 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 OAI98046.1 - 1.2e-07 31.4 0.0 0.0001 22.0 0.0 3.1 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Med15 PF09606.10 OAI98046.1 - 0.93 8.1 6.1 1.3 7.6 6.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Inhibitor_G39P PF11417.8 OAI98049.1 - 0.036 14.6 0.3 0.081 13.5 0.3 1.5 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P MqsA_antitoxin PF15731.5 OAI98049.1 - 0.18 11.9 0.4 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA GMC_oxred_N PF00732.19 OAI98062.1 - 1.4e-30 106.7 0.0 2.4e-30 105.9 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAI98062.1 - 5.3e-05 23.4 0.1 0.00015 21.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAI98062.1 - 0.00044 19.4 0.1 0.00063 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAI98062.1 - 0.00083 18.5 0.1 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAI98062.1 - 0.0014 18.3 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAI98062.1 - 0.008 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAI98062.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 OAI98062.1 - 0.031 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pinin_SDK_N PF04697.13 OAI98064.1 - 6.5 7.4 10.4 1.4 9.5 2.3 2.1 1 1 1 2 2 2 0 pinin/SDK conserved region DDE_1 PF03184.19 OAI98068.1 - 3.6e-18 65.8 0.0 6.2e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAI98068.1 - 4e-08 33.2 0.0 1.5e-07 31.3 0.0 2.0 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 OAI98068.1 - 0.0056 16.4 0.1 0.022 14.5 0.0 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Histone_HNS PF00816.21 OAI98068.1 - 0.079 13.8 0.2 8.3 7.3 0.5 2.4 2 0 0 2 2 2 0 H-NS histone family RVT_1 PF00078.27 OAI98083.1 - 0.00024 20.7 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAI98083.1 - 0.082 12.7 0.2 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Mito_carr PF00153.27 OAI98101.1 - 1.6e-62 207.5 6.5 2.5e-20 72.2 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SPX PF03105.19 OAI98101.1 - 8.5 6.2 10.2 59 3.4 10.2 1.9 1 1 0 1 1 1 0 SPX domain Lipase_GDSL_2 PF13472.6 OAI98106.1 - 0.0024 18.3 0.8 0.0029 18.0 0.1 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family DUF981 PF06168.11 OAI98107.1 - 0.0021 18.0 1.7 0.0031 17.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF981) MFS_1 PF07690.16 OAI98107.1 - 0.008 15.1 2.4 0.011 14.7 2.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 OAI98107.1 - 0.029 14.0 3.3 0.039 13.6 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Arabinose_trans PF04602.12 OAI98107.1 - 0.037 12.9 0.4 0.067 12.0 0.2 1.5 1 1 1 2 2 2 0 Mycobacterial cell wall arabinan synthesis protein MerC PF03203.14 OAI98107.1 - 0.25 11.8 3.1 1.2 9.7 3.2 2.0 1 1 0 1 1 1 0 MerC mercury resistance protein DNA_pol_viral_C PF00336.18 OAI98113.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAI98113.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.22 OAI98114.1 - 0.00027 20.8 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 OAI98114.1 - 0.14 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RT_RNaseH_2 PF17919.1 OAI98120.1 - 9.2e-33 112.3 0.0 3.2e-32 110.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98120.1 - 3.8e-30 104.3 0.0 1.3e-29 102.6 0.0 2.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98120.1 - 7.8e-19 68.1 1.4 1.1e-18 67.6 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAI98120.1 - 0.084 13.5 0.0 0.4 11.4 0.0 2.2 1 0 0 1 1 1 0 Aspartyl protease Bcl-2_BAD PF10514.9 OAI98120.1 - 0.18 12.3 1.7 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD Integrase_H2C2 PF17921.1 OAI98130.1 - 2.4e-16 59.6 0.0 4.9e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAI98130.1 - 1.8e-12 47.5 0.0 5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI98130.1 - 6.2e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAI98130.1 - 1.3e-08 34.6 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI98130.1 - 5.2e-07 29.6 0.0 1.5e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAI98130.1 - 0.013 15.7 0.1 0.038 14.2 0.1 1.8 1 0 0 1 1 1 0 H2C2 zinc finger p450 PF00067.22 OAI98146.1 - 4.7e-32 111.4 0.0 5.4e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Yae1_N PF09811.9 OAI98151.1 - 0.00043 19.9 9.7 0.00075 19.1 9.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal NOA36 PF06524.12 OAI98162.1 - 0.016 14.5 27.0 0.018 14.4 27.0 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 OAI98162.1 - 0.037 13.0 15.3 0.037 13.1 15.3 1.0 1 0 0 1 1 1 0 Paf1 Cwf_Cwc_15 PF04889.12 OAI98162.1 - 0.11 12.2 29.8 0.13 12.0 29.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 OAI98162.1 - 0.25 10.6 24.4 0.27 10.5 24.4 1.0 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpc4 PF05132.14 OAI98162.1 - 0.37 11.2 5.3 0.42 11.0 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myticin-prepro PF10690.9 OAI98162.1 - 0.4 11.0 4.2 0.3 11.4 2.4 1.7 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel RNA_pol_3_Rpc31 PF11705.8 OAI98162.1 - 1.5 9.0 34.2 1.9 8.7 34.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF913 PF06025.12 OAI98162.1 - 1.6 7.6 6.9 1.8 7.5 6.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 OAI98162.1 - 1.7 9.0 13.1 2.1 8.6 13.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 OAI98162.1 - 2.5 7.4 24.9 2.8 7.2 24.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPL5 PF18168.1 OAI98162.1 - 5.4 6.2 9.7 6.4 6.0 9.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SAPS PF04499.15 OAI98162.1 - 6.6 5.4 11.7 6.5 5.4 11.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2076 PF09849.9 OAI98162.1 - 7.6 6.5 18.4 8.8 6.3 18.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Serinc PF03348.15 OAI98162.1 - 7.7 5.3 5.7 8.5 5.2 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.12 OAI98162.1 - 8.3 4.5 32.5 8.7 4.4 32.5 1.0 1 0 0 1 1 1 0 Nop14-like family Peptidase_M16 PF00675.20 OAI98174.1 - 1.8e-39 135.1 0.0 3.3e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAI98174.1 - 3.6e-38 131.4 0.0 6.7e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2607 PF10795.9 OAI98174.1 - 0.028 14.6 0.5 0.066 13.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) PXA PF02194.15 OAI98174.1 - 0.13 12.2 1.4 19 5.2 0.1 3.2 3 0 0 3 3 3 0 PXA domain GPAT_N PF14829.6 OAI98174.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Herpes_LMP2 PF07415.11 OAI98178.1 - 2.8 6.6 3.3 0.68 8.6 0.1 1.6 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Iso_dh PF00180.20 OAI98182.1 - 6.5e-91 305.1 0.0 1.3e-90 304.0 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Synaptobrevin PF00957.21 OAI98183.1 - 1.8e-26 91.8 0.2 2.5e-26 91.3 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 OAI98183.1 - 2.1e-18 66.1 0.0 3.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Actin PF00022.19 OAI98187.1 - 1.1e-73 248.3 0.0 2.3e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 OAI98187.1 - 0.13 12.7 0.1 0.39 11.2 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA baeRF_family10 PF18854.1 OAI98187.1 - 0.17 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 AAA PF00004.29 OAI98190.1 - 2.6e-06 27.9 0.0 3.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAI98190.1 - 0.00015 22.2 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAI98190.1 - 0.00047 20.2 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 OAI98190.1 - 0.00047 19.8 0.0 0.00059 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAI98190.1 - 0.0049 16.6 0.1 0.0059 16.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAI98190.1 - 0.0061 16.7 0.0 0.0078 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAI98190.1 - 0.013 15.7 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAI98190.1 - 0.02 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAI98190.1 - 0.038 14.3 0.1 0.049 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAI98190.1 - 0.057 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAI98190.1 - 0.099 12.4 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 OAI98190.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.6 OAI98190.1 - 0.14 12.3 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Trypan_PARP PF05887.11 OAI98190.1 - 0.15 12.0 7.3 0.21 11.6 7.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NACHT PF05729.12 OAI98190.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 OAI98190.1 - 0.19 12.1 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase EXS PF03124.14 OAI98197.1 - 1.3e-74 251.5 3.5 5.9e-64 216.5 1.2 2.3 2 1 0 2 2 2 2 EXS family Spt5_N PF11942.8 OAI98200.1 - 0.66 11.0 3.0 1.2 10.1 3.0 1.7 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Caskin1-CID PF16600.5 OAI98200.1 - 3.3 8.4 7.2 2.7 8.6 5.8 1.6 1 1 0 1 1 1 0 Caskin1 CASK-interaction domain SRP-alpha_N PF04086.13 OAI98200.1 - 3.4 7.5 5.7 4.1 7.2 5.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Homeodomain PF00046.29 OAI98210.1 - 1.2e-13 50.7 0.5 3.2e-13 49.3 0.5 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 OAI98210.1 - 0.00023 21.0 0.8 0.00057 19.7 0.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain RRN3 PF05327.11 OAI98210.1 - 0.055 12.0 0.5 0.092 11.3 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cytochrome-c551 PF10643.9 OAI98210.1 - 0.077 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 YL1 PF05764.13 OAI98210.1 - 2 8.5 11.5 3.4 7.7 11.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.32 OAI98216.1 - 5.4e-22 77.7 7.0 8.5e-10 39.1 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAI98216.1 - 2.9e-08 33.9 0.3 0.053 13.8 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAI98216.1 - 0.0027 16.7 0.0 0.05 12.6 0.0 2.4 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAI98216.1 - 0.1 11.2 0.1 7.4 5.1 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Retrotrans_gag PF03732.17 OAI98231.1 - 0.00076 19.7 0.5 0.0011 19.2 0.5 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1517 PF07466.11 OAI98231.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3328 PF11807.8 OAI98234.1 - 0.091 12.5 0.1 0.091 12.5 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) DUF3566 PF12089.8 OAI98234.1 - 2.4 8.6 7.4 0.97 9.8 0.1 2.7 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) PQ-loop PF04193.14 OAI98235.1 - 0.023 14.5 0.4 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 PQ loop repeat 60KD_IMP PF02096.20 OAI98239.1 - 2.3e-24 86.2 0.4 3.2e-24 85.7 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Phasin_2 PF09361.10 OAI98239.1 - 0.34 11.2 14.3 0.12 12.7 9.1 2.4 2 0 0 2 2 2 0 Phasin protein DUF4887 PF16228.5 OAI98239.1 - 2.5 8.3 8.6 4.2 7.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DUF3306 PF11748.8 OAI98239.1 - 9.4 7.1 7.6 11 6.9 5.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Peptidase_S10 PF00450.22 OAI98243.1 - 1.2e-98 331.3 0.0 1.5e-98 331.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Collagen PF01391.18 OAI98252.1 - 0.00022 20.9 22.1 0.00022 20.9 22.1 3.8 2 1 1 3 3 3 2 Collagen triple helix repeat (20 copies) DUF4055 PF13264.6 OAI98252.1 - 0.1 12.7 0.3 0.1 12.7 0.3 3.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4055) DUF4071 PF13281.6 OAI98252.1 - 0.41 9.7 2.9 0.65 9.0 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) HTH_Mga PF08280.11 OAI98256.1 - 0.12 12.4 0.3 0.2 11.7 0.3 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain RVT_1 PF00078.27 OAI98269.1 - 1.3e-26 93.5 0.0 2.4e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAAT_C PF08840.11 OAI98269.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Retrotran_gag_2 PF14223.6 OAI98273.1 - 6.7e-23 80.9 0.1 9.1e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 OAI98273.1 - 0.00019 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAI98273.1 - 0.0039 16.8 0.2 0.016 14.8 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) eIF3g PF12353.8 OAI98273.1 - 0.016 15.6 0.6 0.03 14.7 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G RBFA PF02033.18 OAI98273.1 - 0.091 13.2 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A MULE PF10551.9 OAI98280.1 - 2.7e-20 72.6 0.0 5.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAI98280.1 - 7.8e-08 31.6 0.0 1.2e-07 30.9 0.0 1.3 1 1 0 1 1 1 1 Transposase, Mutator family zf-C2H2_10 PF16588.5 OAI98280.1 - 0.022 14.5 2.4 0.051 13.3 2.4 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger DUF4366 PF14283.6 OAI98300.1 - 0.16 12.0 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MAP65_ASE1 PF03999.12 OAI98300.1 - 2.4 6.7 4.2 3.6 6.2 4.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TMEM126 PF07114.11 OAI98310.1 - 0.62 9.4 10.6 0.85 9.0 10.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 TSC22 PF01166.18 OAI98327.1 - 0.0061 16.8 0.4 0.0061 16.8 0.4 2.1 2 0 0 2 2 2 1 TSC-22/dip/bun family HOOK PF05622.12 OAI98327.1 - 0.037 12.2 5.8 0.055 11.6 5.8 1.2 1 0 0 1 1 1 0 HOOK protein GAS PF13851.6 OAI98327.1 - 0.072 12.4 6.2 3 7.1 0.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 OAI98327.1 - 0.2 11.7 10.5 2.3 8.2 1.3 3.2 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 OAI98327.1 - 0.24 12.1 4.1 1.8 9.3 0.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA HAP1_N PF04849.13 OAI98327.1 - 0.63 9.2 9.3 1.9 7.6 0.4 2.4 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF4472 PF14739.6 OAI98327.1 - 1.6 9.5 8.1 9.5 7.0 1.7 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 OAI98327.1 - 2.6 8.6 9.5 6.8 7.2 4.2 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_60s PF00428.19 OAI98328.1 - 7e-21 74.6 9.5 1.1e-20 74.0 9.5 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1631 PF07793.11 OAI98328.1 - 0.0032 16.0 1.2 0.0038 15.7 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) NatB_MDM20 PF09797.9 OAI98335.1 - 0.00061 18.8 0.0 0.00079 18.5 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Collagen_mid PF15984.5 OAI98335.1 - 0.0014 18.4 1.0 0.0017 18.2 1.0 1.1 1 0 0 1 1 1 1 Bacterial collagen, middle region PSK_trans_fac PF07704.11 OAI98335.1 - 0.032 15.0 1.2 0.067 14.0 1.2 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor L27_2 PF09045.10 OAI98335.1 - 0.038 14.0 0.1 3.3 7.7 0.1 2.4 2 0 0 2 2 2 0 L27_2 NTase_sub_bind PF08780.11 OAI98335.1 - 0.094 12.7 0.3 0.23 11.4 0.2 1.7 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like Thymidylat_synt PF00303.19 OAI98344.1 - 1.1e-107 359.1 0.0 1.5e-107 358.7 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 OAI98344.1 - 3.3e-37 128.1 2.0 4.4e-36 124.4 2.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2235 PF09994.9 OAI98351.1 - 1.4e-33 116.5 0.0 1.3e-18 67.4 0.0 2.4 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amelogenin PF02948.15 OAI98368.1 - 0.17 12.5 0.3 17 6.0 0.0 2.1 2 0 0 2 2 2 0 Amelogenin NTP_transferase PF00483.23 OAI98382.1 - 4.1e-38 131.4 0.0 6.4e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 OAI98382.1 - 7.9e-06 25.8 0.1 1.4e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Aminotran_1_2 PF00155.21 OAI98388.1 - 1.3e-18 67.3 0.0 1.9e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SecY PF00344.20 OAI98388.1 - 4.5e-08 32.7 0.0 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 SecY translocase DUF883 PF05957.13 OAI98404.1 - 0.09 13.4 0.3 0.14 12.8 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Nbl1_Borealin_N PF10444.9 OAI98404.1 - 0.23 11.1 2.0 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal IDO PF01231.18 OAI98412.1 - 1.9e-124 415.8 0.0 4.6e-124 414.5 0.0 1.6 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase TFIIA PF03153.13 OAI98412.1 - 7.4 6.5 11.3 2.5 8.0 1.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GLE1 PF07817.13 OAI98415.1 - 1.9e-71 240.3 0.0 2.8e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 GLE1-like protein eIF3_subunit PF08597.10 OAI98415.1 - 0.0015 18.5 17.2 0.0033 17.4 17.2 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit V_ATPase_I PF01496.19 OAI98415.1 - 0.23 9.4 4.9 0.28 9.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPP4R2 PF09184.11 OAI98415.1 - 0.32 10.5 15.5 8.8 5.8 0.0 2.5 2 0 0 2 2 2 0 PPP4R2 DUF4407 PF14362.6 OAI98415.1 - 2 7.7 14.7 3.6 6.9 14.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4746 PF15928.5 OAI98415.1 - 2.9 7.2 15.2 5.1 6.4 15.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PA26 PF04636.13 OAI98415.1 - 6.6 5.5 6.7 10 4.9 6.7 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) WYL PF13280.6 OAI98425.1 - 1.2e-26 93.8 0.1 1.9e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 WYL domain HTH_Tnp_Tc3_2 PF01498.18 OAI98425.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 Transposase TPR_10 PF13374.6 OAI98430.1 - 8.7e-14 50.9 36.2 0.0013 18.5 0.6 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAI98430.1 - 1.1e-12 48.0 37.9 2.6e-06 27.6 3.6 9.3 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAI98430.1 - 3e-07 30.1 17.5 2.5 8.5 0.0 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAI98430.1 - 2e-06 27.4 1.8 0.36 10.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAI98430.1 - 3e-05 24.0 14.3 1.5 8.9 0.1 6.6 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 OAI98430.1 - 4.8e-05 23.1 18.7 0.33 11.2 0.1 8.3 9 0 0 9 9 8 1 Tetratricopeptide repeat Sec16_C PF12931.7 OAI98430.1 - 0.0055 16.4 1.9 5.8 6.5 0.0 3.4 2 2 1 3 3 3 1 Sec23-binding domain of Sec16 DUF3856 PF12968.7 OAI98430.1 - 0.014 15.5 4.8 1.2 9.2 0.1 4.2 3 1 1 5 5 5 0 Domain of Unknown Function (DUF3856) DUF3681 PF12442.8 OAI98430.1 - 0.02 15.3 1.7 24 5.5 0.0 4.5 4 1 1 5 5 4 0 Protein of unknown function (DUF3681) TPR_7 PF13176.6 OAI98430.1 - 0.027 14.5 10.4 44 4.4 0.0 7.3 7 2 0 7 7 6 0 Tetratricopeptide repeat DUF627 PF04781.12 OAI98430.1 - 0.037 14.0 4.3 7.5 6.6 0.1 5.2 4 2 2 6 6 6 0 Protein of unknown function (DUF627) Utp11 PF03998.13 OAI98430.1 - 0.073 13.0 0.2 12 5.8 0.0 3.1 1 1 1 3 3 3 0 Utp11 protein MCRS_N PF13325.6 OAI98430.1 - 0.09 12.8 0.4 11 5.9 0.0 3.3 3 1 0 4 4 4 0 N-terminal region of micro-spherule protein DUF4996 PF16387.5 OAI98430.1 - 0.093 13.2 0.0 13 6.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function TPR_14 PF13428.6 OAI98430.1 - 0.5 11.3 19.9 61 4.8 0.3 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAI98430.1 - 0.79 10.4 28.0 0.12 13.0 1.4 7.3 6 4 1 7 7 7 0 Tetratricopeptide repeat RT_RNaseH_2 PF17919.1 OAI98437.1 - 1.8e-14 53.5 0.0 3.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAI98437.1 - 0.00049 20.7 0.1 0.0012 19.4 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI98437.1 - 0.007 16.9 0.0 0.018 15.6 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 OAI98437.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RVP PF00077.20 OAI98437.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Phage_integrase PF00589.22 OAI98443.1 - 0.032 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family DNA_pol_viral_C PF00336.18 OAI98444.1 - 0.0033 16.8 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAI98444.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like DUF89 PF01937.19 OAI98459.1 - 1.1e-106 356.8 0.0 1.7e-106 356.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 TPR_19 PF14559.6 OAI98459.1 - 0.026 15.0 0.5 0.076 13.5 0.5 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat ArgoL2 PF16488.5 OAI98472.1 - 5e-09 36.4 0.2 7.7e-09 35.8 0.2 1.3 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 OAI98472.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 1 0 1 1 1 1 PAZ domain Aconitase_B_N PF11791.8 OAI98472.1 - 0.037 14.1 0.1 0.052 13.6 0.1 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain AA_permease_2 PF13520.6 OAI98482.1 - 2.2e-08 33.4 5.1 1.6e-06 27.2 4.2 2.0 1 1 1 2 2 2 2 Amino acid permease adh_short PF00106.25 OAI98488.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RVT_1 PF00078.27 OAI98513.1 - 4.8e-24 85.1 0.0 8.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI98513.1 - 2.7e-23 81.9 0.0 6.6e-14 51.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98513.1 - 8.2e-18 64.6 0.0 3e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI98513.1 - 4.8e-13 49.0 0.1 9.9e-13 48.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI98513.1 - 2.3e-12 47.1 0.0 7.6e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Polysacc_deac_1 PF01522.21 OAI98521.1 - 3.2e-27 94.9 0.0 6.6e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 OAI98521.1 - 0.2 9.7 13.6 0.72 7.9 13.6 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen RVT_1 PF00078.27 OAI98531.1 - 3.1e-25 89.0 0.0 5.2e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI98531.1 - 1.2e-15 57.4 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98531.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAI98531.1 - 0.0024 18.5 0.2 0.0092 16.6 0.2 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI98531.1 - 0.054 14.1 0.1 0.15 12.6 0.1 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease PX PF00787.24 OAI98539.1 - 4.5e-21 75.0 0.0 6.9e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 PX domain zf-CCHC PF00098.23 OAI98543.1 - 0.0052 16.8 2.0 0.0092 16.0 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAI98543.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease SPX PF03105.19 OAI98552.1 - 1.3e-67 229.4 23.4 1e-48 167.2 11.1 2.2 1 1 1 2 2 2 2 SPX domain zf-C3HC4_3 PF13920.6 OAI98552.1 - 5.2e-07 29.4 7.0 5.2e-07 29.4 7.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAI98552.1 - 2.2e-06 27.5 7.3 3.9e-06 26.6 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAI98552.1 - 1e-05 25.6 6.7 2.1e-05 24.6 6.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAI98552.1 - 1.7e-05 25.1 10.3 3.7e-05 24.0 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 OAI98552.1 - 1.7e-05 24.5 7.6 3.2e-05 23.7 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 OAI98552.1 - 0.00035 20.3 8.6 0.00065 19.5 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAI98552.1 - 0.00037 20.4 6.9 0.00083 19.3 6.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAI98552.1 - 0.013 15.3 2.3 0.026 14.3 2.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 OAI98552.1 - 0.017 15.2 8.4 0.036 14.1 8.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 OAI98552.1 - 0.11 12.8 6.0 0.27 11.6 6.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-P11 PF03854.14 OAI98552.1 - 1.8 8.3 6.1 3.5 7.4 6.1 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF373 PF04123.13 OAI98559.1 - 5.8 6.3 13.5 3.3 7.0 2.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF373) Pyridoxal_deC PF00282.19 OAI98563.1 - 2.2e-29 102.3 0.0 1.1e-27 96.7 0.0 2.0 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Phage_integrase PF00589.22 OAI98570.1 - 0.0001 22.1 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAI98570.1 - 0.13 12.1 0.3 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) DNA_pol_viral_C PF00336.18 OAI98571.1 - 0.012 15.0 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain WD40 PF00400.32 OAI98577.1 - 3.4e-42 141.6 4.4 9.4e-09 35.8 0.1 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Tup_N PF08581.10 OAI98577.1 - 1.2e-18 67.2 2.8 1.2e-18 67.2 2.8 2.3 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 OAI98577.1 - 7.1e-18 64.7 0.0 1.6e-05 25.1 0.0 4.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAI98577.1 - 1.8e-09 37.3 0.0 0.0043 16.4 0.0 3.4 4 0 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 OAI98577.1 - 9.1e-06 24.8 0.0 1.1 8.2 0.0 4.3 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIA PF03153.13 OAI98577.1 - 0.00041 20.5 38.4 0.00041 20.5 38.4 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PD40 PF07676.12 OAI98577.1 - 0.00056 19.8 0.1 17 5.5 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 OAI98577.1 - 0.0089 14.7 0.2 4.4 5.8 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 OAI98577.1 - 0.079 11.5 0.1 0.24 9.9 0.1 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain RRM_1 PF00076.22 OAI98590.1 - 1.2e-08 34.6 0.0 2.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LEA_4 PF02987.16 OAI98590.1 - 0.00082 19.4 4.8 0.00082 19.4 4.8 2.8 2 1 1 3 3 3 1 Late embryogenesis abundant protein YtxH PF12732.7 OAI98590.1 - 0.0096 16.4 5.7 0.0096 16.4 5.7 3.5 3 2 1 4 4 4 1 YtxH-like protein RRM_occluded PF16842.5 OAI98590.1 - 0.01 15.7 1.7 0.016 15.0 0.0 2.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif ApoLp-III PF07464.11 OAI98590.1 - 0.48 10.5 9.7 0.16 12.1 2.1 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 OAI98590.1 - 0.66 10.6 9.1 0.081 13.5 2.3 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HMGL-like PF00682.19 OAI98595.1 - 2.5e-73 246.9 0.0 3.5e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 OAI98595.1 - 4e-18 65.6 0.1 3.8e-09 36.5 0.0 2.6 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Myco_19_kDa PF05481.12 OAI98595.1 - 0.036 14.3 0.2 0.071 13.4 0.2 1.5 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Bax1-I PF01027.20 OAI98602.1 - 4.8e-46 157.2 19.7 5.6e-46 157.0 19.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 OAI98602.1 - 0.027 14.1 16.0 0.091 12.3 16.0 1.9 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF3464 PF11947.8 OAI98602.1 - 0.88 9.3 7.2 0.12 12.1 2.3 2.0 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 Pox_I5 PF04713.12 OAI98602.1 - 4.1 7.5 8.6 1 9.4 0.2 2.8 2 1 1 3 3 3 0 Poxvirus protein I5 Nop53 PF07767.11 OAI98603.1 - 2.3e-29 103.0 0.6 5e-29 101.9 0.6 1.5 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PGAP1 PF07819.13 OAI98611.1 - 0.00082 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 OAI98611.1 - 0.036 14.7 0.0 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3678 PF12435.8 OAI98611.1 - 0.23 10.9 3.6 0.46 9.9 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DUF1980 PF09323.10 OAI98611.1 - 8 6.3 6.2 1.9 8.3 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DNA_pol_viral_C PF00336.18 OAI98619.1 - 0.013 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.27 OAI98619.1 - 0.027 14.0 0.0 0.083 12.4 0.0 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SAVED PF18145.1 OAI98619.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain OPT PF03169.15 OAI98625.1 - 1.1e-92 311.6 41.7 1.3e-92 311.4 41.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3306 PF11748.8 OAI98625.1 - 1.3 9.9 3.3 2.4 9.0 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Spt5_N PF11942.8 OAI98654.1 - 2.9 8.9 7.9 2.8 9.0 4.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CBFB_NFYA PF02045.15 OAI98655.1 - 6.6e-18 65.1 26.4 1.5e-12 47.9 1.0 3.4 3 1 0 3 3 3 2 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF3915 PF13054.6 OAI98655.1 - 2.7 8.0 5.4 0.48 10.4 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Asp_protease_2 PF13650.6 OAI98669.1 - 0.00075 20.1 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI98669.1 - 0.0031 18.1 0.0 0.0067 17.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pyocin_S PF06958.12 OAI98670.1 - 1.3 9.6 3.9 8.6 6.9 0.2 2.1 2 0 0 2 2 2 0 S-type Pyocin AA_permease PF00324.21 OAI98677.1 - 6.5e-28 97.6 3.2 7.8e-28 97.3 3.2 1.0 1 0 0 1 1 1 1 Amino acid permease SRP68 PF16969.5 OAI98678.1 - 3.7 6.4 5.5 5.3 5.9 5.5 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 CRAL_TRIO PF00650.20 OAI98690.1 - 1.2e-16 60.8 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain G_glu_transpept PF01019.21 OAI98691.1 - 1.5e-136 456.2 0.0 1.8e-136 455.9 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Exo_endo_phos PF03372.23 OAI98697.1 - 0.00046 19.8 0.5 0.002 17.7 0.4 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAI98697.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase RVT_1 PF00078.27 OAI98698.1 - 0.00082 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TFIID_20kDa PF03847.13 OAI98719.1 - 9.5e-32 109.3 0.3 1.5e-31 108.7 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 OAI98719.1 - 0.0094 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAI98719.1 - 0.018 15.1 0.0 0.076 13.1 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Occludin_ELL PF07303.13 OAI98719.1 - 0.066 13.9 0.1 0.066 13.9 0.1 2.4 3 0 0 3 3 3 0 Occludin homology domain Histone PF00125.24 OAI98719.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 RT_RNaseH_2 PF17919.1 OAI98725.1 - 1.1e-21 76.7 0.0 1.2e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98725.1 - 6.3e-21 74.9 0.0 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAI98725.1 - 1.4e-16 60.6 0.0 1.1e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAI98725.1 - 4.6e-12 46.2 0.0 1.2e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAI98725.1 - 8e-07 29.1 1.6 2.6e-06 27.4 1.6 1.9 1 1 0 1 1 1 1 Integrase zinc binding domain SNARE_assoc PF09335.11 OAI98731.1 - 6.3e-22 78.3 5.6 1.4e-13 51.4 0.0 3.3 4 0 0 4 4 4 2 SNARE associated Golgi protein Peptidase_C48 PF02902.19 OAI98740.1 - 1.6e-12 47.8 0.1 1.6e-12 47.8 0.1 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DUF5352 PF17303.2 OAI98740.1 - 0.078 12.8 0.0 0.078 12.8 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5352) SWIM PF04434.17 OAI98740.1 - 0.13 12.0 0.8 0.26 11.0 0.8 1.5 1 0 0 1 1 1 0 SWIM zinc finger CMS1 PF14617.6 OAI98740.1 - 0.56 9.5 4.0 1.3 8.3 4.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MTP18 PF10558.9 OAI98748.1 - 7.6e-30 104.1 0.3 9.6e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DSHCT PF08148.12 OAI98749.1 - 9e-21 74.2 0.2 1.8e-20 73.2 0.2 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 OAI98749.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Dynamitin PF04912.14 OAI98749.1 - 0.022 14.1 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Dynamitin LppA PF16708.5 OAI98756.1 - 0.057 13.3 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Edc3_linker PF16598.5 OAI98776.1 - 1.3 9.8 9.1 2.6 8.8 9.1 1.5 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 CBFD_NFYB_HMF PF00808.23 OAI98789.1 - 2.4e-14 53.4 0.0 2.6e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAI98789.1 - 0.00031 21.1 0.0 0.00032 21.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 OAI98789.1 - 0.027 14.6 0.1 0.029 14.5 0.1 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TRAM PF01938.20 OAI98789.1 - 0.054 13.5 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 TRAM domain 5-FTHF_cyc-lig PF01812.20 OAI98790.1 - 1e-28 100.5 0.7 1.2e-26 93.8 0.0 2.5 2 1 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family PMT PF02366.18 OAI98796.1 - 1e-08 35.1 3.1 0.0018 17.9 0.9 2.3 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Ycf9 PF01737.17 OAI98796.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.1 2 1 0 2 2 2 0 YCF9 DNA_pol_phi PF04931.13 OAI98806.1 - 3.6e-102 342.9 0.0 3.3e-101 339.7 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase phi HEAT PF02985.22 OAI98806.1 - 0.082 13.2 0.3 18 5.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat TMEM135_C_rich PF15982.5 OAI98813.1 - 0.0012 19.5 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 RT_RNaseH_2 PF17919.1 OAI98823.1 - 1.9e-29 101.7 0.0 4.8e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98823.1 - 2.2e-26 92.2 0.0 5.6e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98823.1 - 7.5e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCDHK_Adom3 PF10436.9 OAI98833.1 - 0.099 12.5 2.1 0.13 12.1 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase RAG1 PF12940.7 OAI98833.1 - 0.12 10.5 5.3 0.15 10.1 5.3 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase TMCO5 PF14992.6 OAI98833.1 - 0.48 10.0 18.9 0.62 9.6 18.9 1.0 1 0 0 1 1 1 0 TMCO5 family YjbH PF06082.11 OAI98833.1 - 0.89 8.3 8.8 0.99 8.1 8.8 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH CDPS PF16715.5 OAI98833.1 - 5.1 6.7 9.6 2 8.0 5.1 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase Neur_chan_memb PF02932.16 OAI98833.1 - 7.2 6.6 8.9 9 6.3 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF334 PF03904.13 OAI98833.1 - 9.8 5.6 13.1 6.3 6.3 11.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Uricase PF01014.18 OAI98834.1 - 3.8e-59 198.6 0.0 1.2e-32 112.9 0.0 2.3 2 0 0 2 2 2 2 Uricase 6PGD PF00393.19 OAI98842.1 - 8e-109 363.5 0.0 8.9e-109 363.3 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Aldo_ket_red PF00248.21 OAI98843.1 - 1.5e-53 181.9 0.0 1.7e-53 181.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DBD_Tnp_Mut PF03108.15 OAI98849.1 - 2.1e-10 40.4 0.9 4e-10 39.5 0.9 1.4 1 0 0 1 1 1 1 MuDR family transposase zf-ribbon_3 PF13248.6 OAI98849.1 - 0.15 11.6 1.2 0.4 10.2 1.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain TSGP1 PF07771.11 OAI98857.1 - 3.6 7.8 7.0 0.19 11.9 1.0 1.9 2 0 0 2 2 2 0 Tick salivary peptide group 1 zf-BED PF02892.15 OAI98866.1 - 4.2e-05 23.5 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger DUF1566 PF07603.11 OAI98866.1 - 0.079 13.3 0.1 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1566) Dimer_Tnp_hAT PF05699.14 OAI98867.1 - 2.9e-11 43.0 0.0 5.9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAI98867.1 - 3.4e-06 27.4 0.4 1.4e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) RT_RNaseH_2 PF17919.1 OAI98875.1 - 2.3e-32 111.0 0.0 5.5e-32 109.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAI98875.1 - 3.9e-28 97.8 0.0 1.1e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98875.1 - 2.4e-20 73.0 0.0 4.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAI98885.1 - 2.7e-23 81.9 0.0 7.1e-14 51.7 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAI98885.1 - 1.8e-21 76.7 0.0 3.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAI98885.1 - 3.2e-17 62.7 0.0 2.1e-11 44.0 0.0 2.7 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI98885.1 - 8.2e-15 54.7 0.0 1.7e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI98885.1 - 0.001 19.3 0.0 0.24 11.6 0.0 2.5 1 1 1 2 2 2 2 Integrase core domain DDE_1 PF03184.19 OAI98903.1 - 7.3e-22 77.9 0.0 9.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAI98903.1 - 0.038 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease REV PF00424.18 OAI98927.1 - 0.2 11.7 6.1 0.32 11.1 3.2 2.6 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) FAM60A PF15396.6 OAI98927.1 - 7.9 6.4 8.6 0.6 10.1 2.4 2.0 2 0 0 2 2 2 0 Protein Family FAM60A RT_RNaseH PF17917.1 OAI98945.1 - 1.4e-11 44.6 0.0 2.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI98945.1 - 3.3e-06 27.1 0.0 7.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1974 PF09317.11 OAI98954.1 - 0.0054 16.3 0.1 0.0099 15.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) Strabismus PF06638.11 OAI98954.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Strabismus protein MFS_1 PF07690.16 OAI98961.1 - 9.7e-10 37.9 23.3 9.7e-10 37.9 23.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily FHA PF00498.26 OAI98978.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 FHA domain Clat_adaptor_s PF01217.20 OAI99000.1 - 1.2e-53 180.9 1.3 1.3e-53 180.8 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mito_carr PF00153.27 OAI99001.1 - 1.2e-53 179.0 0.3 8e-20 70.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 OAI99010.1 - 1.9e-31 109.4 0.0 3.1e-31 108.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI99010.1 - 4.6e-17 62.2 0.0 9.2e-17 61.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAI99010.1 - 0.0012 17.8 0.0 0.0024 16.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pantoate_transf PF02548.15 OAI99022.1 - 0.026 13.9 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase RVT_2 PF07727.14 OAI99033.1 - 1e-67 228.3 0.0 1.4e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAI99033.1 - 4.3e-17 62.4 0.3 4.1e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAI99033.1 - 1.3e-05 24.9 0.0 3.2e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAI99033.1 - 0.0027 17.4 0.1 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain ICMT PF04140.14 OAI99040.1 - 7.6e-14 51.9 0.4 3e-13 50.0 0.4 1.8 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAI99040.1 - 1.6e-06 28.5 0.7 5.9e-06 26.6 0.7 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 OAI99040.1 - 0.012 14.4 0.0 0.64 8.7 0.0 2.1 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family TRAPPC10 PF12584.8 OAI99050.1 - 9.6e-26 90.4 0.0 1.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF1279 PF06916.13 OAI99051.1 - 0.022 15.3 0.0 0.32 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) MSA-2c PF12238.8 OAI99051.1 - 0.93 9.5 5.7 1.6 8.7 5.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c E1-E2_ATPase PF00122.20 OAI99063.1 - 1e-50 171.8 0.0 1.7e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OAI99063.1 - 9e-11 41.3 0.0 2.8e-10 39.7 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DnaJ PF00226.31 OAI99076.1 - 0.00022 21.3 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 OAI99076.1 - 0.0031 17.3 1.1 0.031 14.1 1.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAI99076.1 - 0.055 13.8 0.7 0.055 13.8 0.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAI99076.1 - 0.37 11.0 13.8 0.033 14.3 1.6 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Carboxyl_trans PF01039.22 OAI99096.1 - 2.2e-134 448.8 0.0 2.8e-134 448.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 OAI99096.1 - 0.0072 16.2 0.1 3.2 7.6 0.0 2.7 3 0 0 3 3 3 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ECH_1 PF00378.20 OAI99096.1 - 0.057 12.7 0.5 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Alpha-amylase PF00128.24 OAI99114.1 - 0.00034 20.3 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CK_II_beta PF01214.18 OAI99132.1 - 6e-75 251.1 0.1 1.5e-74 249.8 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit BSP_II PF05432.11 OAI99132.1 - 0.097 12.4 23.6 0.19 11.4 23.6 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.13 OAI99132.1 - 0.66 9.9 29.4 0.048 13.6 23.1 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 OAI99132.1 - 0.95 9.3 12.6 0.28 11.0 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein 51 PPP4R2 PF09184.11 OAI99132.1 - 8.2 5.9 19.1 13 5.3 19.1 1.2 1 0 0 1 1 1 0 PPP4R2 zf-CCHC PF00098.23 OAI99142.1 - 2.8e-05 24.0 2.9 4.5e-05 23.3 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAI99142.1 - 0.00039 20.2 2.1 0.00074 19.3 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Yae1_N PF09811.9 OAI99142.1 - 0.00092 18.9 10.2 0.0023 17.6 10.2 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal zf-CCHC_5 PF14787.6 OAI99142.1 - 0.001 18.7 0.7 0.0019 17.8 0.7 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Dsh_C PF12316.8 OAI99177.1 - 0.0013 19.2 5.8 0.0013 19.2 5.8 2.1 2 0 0 2 2 2 1 Segment polarity protein dishevelled (Dsh) C terminal CAC1F_C PF16885.5 OAI99177.1 - 0.21 11.2 4.2 0.28 10.8 4.2 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Asp_protease_2 PF13650.6 OAI99190.1 - 1.9e-05 25.2 0.1 4.7e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAI99190.1 - 0.0036 17.8 0.0 0.01 16.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease dUTPase PF00692.19 OAI99190.1 - 0.0048 16.6 0.0 0.0097 15.6 0.0 1.4 1 0 0 1 1 1 1 dUTPase Retrotrans_gag PF03732.17 OAI99190.1 - 0.015 15.6 0.2 0.027 14.7 0.2 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVP PF00077.20 OAI99190.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Nucleo_P87 PF07267.11 OAI99198.1 - 0.49 9.2 3.8 0.72 8.6 3.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GATA PF00320.27 OAI99210.1 - 4.9e-05 22.9 4.8 0.00013 21.5 3.8 2.2 1 1 1 2 2 2 1 GATA zinc finger ADK_lid PF05191.14 OAI99210.1 - 0.23 11.4 1.9 0.49 10.4 1.9 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid IFRD_C PF04836.12 OAI99223.1 - 0.014 16.0 0.0 0.036 14.7 0.0 1.8 1 0 0 1 1 1 0 Interferon-related protein conserved region DNA_pol_viral_C PF00336.18 OAI99223.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Rep_fac_C PF08542.11 OAI99236.1 - 4.7e-18 65.4 0.0 9.8e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAI99236.1 - 1.6e-17 64.2 0.0 6.5e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAI99236.1 - 2.5e-15 56.6 0.0 3.3e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 OAI99236.1 - 8.8e-10 38.8 0.0 2.4e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 OAI99236.1 - 1.1e-05 25.3 0.2 0.00044 20.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 OAI99236.1 - 2.6e-05 23.5 0.0 3.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAI99236.1 - 3.1e-05 23.8 0.0 7.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OAI99236.1 - 3.5e-05 24.0 0.1 0.00012 22.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 OAI99236.1 - 5.7e-05 23.1 0.1 0.00024 21.1 0.0 2.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 OAI99236.1 - 9.8e-05 22.1 0.0 0.00025 20.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAI99236.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 OAI99236.1 - 0.00023 21.0 0.0 0.00086 19.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 OAI99236.1 - 0.00034 20.9 0.1 0.088 13.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 OAI99236.1 - 0.0004 20.3 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAI99236.1 - 0.00051 20.1 0.0 0.002 18.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 OAI99236.1 - 0.00061 19.6 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAI99236.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 OAI99236.1 - 0.0055 16.7 0.0 0.25 11.3 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 OAI99236.1 - 0.0056 16.1 0.1 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein AAA_19 PF13245.6 OAI99236.1 - 0.0067 16.8 0.0 0.016 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAI99236.1 - 0.0082 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 OAI99236.1 - 0.023 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 OAI99236.1 - 0.044 13.5 0.1 0.46 10.2 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 OAI99236.1 - 0.05 14.1 0.0 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 OAI99236.1 - 0.064 13.0 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAI99236.1 - 0.091 12.3 0.0 0.25 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAI99236.1 - 0.12 11.7 0.0 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.7 OAI99236.1 - 0.14 11.1 0.1 2.9 6.7 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain COX14 PF14880.6 OAI99237.1 - 0.0038 17.0 0.2 0.0064 16.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c assembly FAD_binding_4 PF01565.23 OAI99248.1 - 3.2e-16 59.3 5.7 3.3e-09 36.6 0.0 3.9 4 0 0 4 4 4 2 FAD binding domain BBE PF08031.12 OAI99248.1 - 1.2e-06 28.6 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Med3 PF11593.8 OAI99248.1 - 0.062 12.5 15.4 0.11 11.7 15.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MCLC PF05934.11 OAI99248.1 - 4.5 5.9 10.4 6.7 5.3 10.4 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) SH3_1 PF00018.28 OAI99250.1 - 7.8e-11 41.4 0.0 1.3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAI99250.1 - 2.6e-08 33.6 0.0 4.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAI99250.1 - 2.2e-07 30.4 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Lipocalin_2 PF08212.12 OAI99261.1 - 1.7e-16 60.4 0.0 2.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin_2 PF08212.12 OAI99262.1 - 2.4e-07 30.8 0.0 6.5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Lipocalin-like domain Ribosomal_L44 PF00935.19 OAI99272.1 - 0.057 13.9 1.4 0.057 13.9 1.4 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 EBV-NA3 PF05009.12 OAI99272.1 - 0.12 11.9 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) RNA_polI_A34 PF08208.11 OAI99272.1 - 1.3 9.1 11.5 2.5 8.2 11.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 OAI99272.1 - 9.3 4.4 9.2 0.21 9.8 2.8 1.3 2 0 0 2 2 2 0 CDC45-like protein DDE_3 PF13358.6 OAI99273.1 - 2.2e-19 69.7 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAI99273.1 - 0.00059 20.4 1.5 0.0013 19.3 0.2 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAI99273.1 - 0.038 13.6 1.4 0.21 11.3 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn helix HTH_29 PF13551.6 OAI99273.1 - 0.064 13.3 0.3 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix AAA PF00004.29 OAI99286.1 - 8.1e-17 61.9 0.0 9e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LSM PF01423.22 OAI99294.1 - 9.4e-15 54.1 0.0 1.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAI99294.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Hfq protein PRP3 PF08572.10 OAI99295.1 - 8.3e-67 225.2 6.3 8.3e-67 225.2 6.3 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 OAI99295.1 - 3.4e-35 121.3 1.1 5e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Pannexin_like PF12534.8 OAI99295.1 - 0.76 8.8 3.6 1.3 8.1 3.6 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 TPR_10 PF13374.6 OAI99311.1 - 8.6e-12 44.5 26.1 0.0023 17.7 0.7 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAI99311.1 - 1.1e-08 35.3 33.1 0.012 15.9 0.7 8.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAI99311.1 - 1e-07 31.5 18.7 0.045 13.9 0.4 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAI99311.1 - 1.2e-06 28.8 19.0 0.06 14.2 1.1 8.1 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAI99311.1 - 0.00045 20.2 5.6 11 6.5 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 OAI99311.1 - 0.022 15.0 3.2 34 5.0 0.0 4.9 5 0 0 5 5 4 0 PPR repeat ANAPC5 PF12862.7 OAI99311.1 - 0.022 14.8 14.9 0.67 10.1 0.1 5.7 2 2 3 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_1 PF00515.28 OAI99311.1 - 0.027 14.3 11.0 0.31 10.9 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAI99311.1 - 0.05 12.4 3.8 2.8 6.6 0.3 3.4 3 2 1 4 4 4 0 Fungal protein kinase MIT PF04212.18 OAI99311.1 - 0.077 13.1 9.6 6.2 7.0 1.5 4.9 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 OAI99311.1 - 0.18 11.9 6.3 11 6.3 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat REV PF00424.18 OAI99311.1 - 0.81 9.8 6.4 8.8 6.4 0.3 4.0 5 0 0 5 5 4 0 REV protein (anti-repression trans-activator protein) PPR_1 PF12854.7 OAI99311.1 - 3.6 7.4 5.6 2.3 8.0 0.1 3.0 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 OAI99311.1 - 6.5 7.6 11.9 37 5.3 0.4 6.2 7 2 1 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAI99311.1 - 7.2 7.6 25.0 20 6.2 0.8 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 OAI99324.1 - 3.1e-93 311.1 0.0 2.3e-82 275.6 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 OAI99324.1 - 1.3e-40 138.5 0.2 5e-40 136.7 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 OAI99324.1 - 1.8e-09 37.4 0.0 3.4e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAI99324.1 - 4.8e-09 36.1 0.0 1.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 OAI99324.1 - 9.6e-06 25.2 0.1 0.011 15.1 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAI99324.1 - 5.9e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAI99324.1 - 0.0002 21.4 0.0 0.00061 19.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Peptidase_M17_N PF02789.17 OAI99324.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain RVT_3 PF13456.6 OAI99336.1 - 0.0022 17.8 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Retrotrans_gag PF03732.17 OAI99357.1 - 1.3e-11 44.6 0.6 2.4e-11 43.8 0.2 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAI99357.1 - 0.0083 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) UDPGT PF00201.18 OAI99370.1 - 7.4e-14 51.4 0.1 1.1e-13 50.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GHMP_kinases_C PF08544.13 OAI99370.1 - 0.078 13.4 0.1 4.2 7.8 0.1 2.5 1 1 0 1 1 1 0 GHMP kinases C terminal UDPGT PF00201.18 OAI99371.1 - 7.5e-13 48.1 0.1 9.5e-13 47.8 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase MULE PF10551.9 OAI99385.1 - 2.7e-12 46.9 0.0 7.9e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAI99385.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family TT_ORF2 PF02957.15 OAI99385.1 - 0.033 15.1 2.1 0.077 13.9 2.1 1.6 1 0 0 1 1 1 0 TT viral ORF2 Sigma70_ner PF04546.13 OAI99385.1 - 0.042 13.7 0.3 0.079 12.8 0.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1670 PF07900.11 OAI99402.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) RT_RNaseH_2 PF17919.1 OAI99402.1 - 0.081 13.0 0.1 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Spectrin PF00435.21 OAI99422.1 - 0.0014 19.1 0.5 0.0021 18.5 0.5 1.3 1 0 0 1 1 1 1 Spectrin repeat DMPK_coil PF08826.10 OAI99422.1 - 0.0078 16.3 0.4 0.02 15.0 0.4 1.7 1 0 0 1 1 1 1 DMPK coiled coil domain like DUF722 PF05263.11 OAI99422.1 - 0.014 15.6 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Scaffolding_pro PF11418.8 OAI99422.1 - 0.045 14.3 0.2 0.46 11.1 0.0 2.0 2 0 0 2 2 2 0 Phi29 scaffolding protein Cep57_MT_bd PF06657.13 OAI99422.1 - 0.051 14.0 0.6 7.9 7.0 0.0 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FUSC PF04632.12 OAI99422.1 - 0.13 10.7 1.0 0.15 10.6 1.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIP-T3_C PF17749.1 OAI99422.1 - 0.19 11.7 2.4 0.32 11.0 2.4 1.6 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region UPF0029 PF01205.19 OAI99435.1 - 1.7e-28 99.0 0.0 4.4e-28 97.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 OAI99435.1 - 0.0014 18.9 1.4 0.026 14.8 1.3 2.3 1 1 0 1 1 1 1 RWD domain RVT_1 PF00078.27 OAI99481.1 - 3.1e-32 111.9 0.0 4.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAI99481.1 - 1.6e-11 44.6 0.0 3.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAI99481.1 - 7.9e-07 28.9 0.1 2.1e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Peroxidase_2 PF01328.17 OAI99493.1 - 7.6e-43 147.2 0.0 1.2e-42 146.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 zf-C2H2 PF00096.26 OAI99506.1 - 0.0015 18.8 1.6 0.0016 18.8 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAI99506.1 - 0.076 13.9 0.1 0.19 12.6 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger RVT_2 PF07727.14 OAI99524.1 - 5.3e-51 173.6 0.0 3e-48 164.6 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAI99524.1 - 6e-17 61.9 0.0 3e-16 59.7 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAI99524.1 - 1.9e-06 27.6 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAI99524.1 - 0.15 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain zf-CCHC PF00098.23 OAI99524.1 - 1.3 9.3 3.4 3.2 8.0 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAI99524.1 - 3.4 7.6 5.0 11 6.0 5.0 1.9 1 0 0 1 1 1 0 Zinc knuckle TOH_N PF12549.8 OAI99536.1 - 0.12 12.2 0.6 1.2e+02 2.7 0.0 3.3 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal Octopine_DH PF02317.17 OAI99546.1 - 0.00084 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF616 PF04765.13 OAI99546.1 - 0.033 13.4 0.2 0.047 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF616) ATPase PF06745.13 OAI99546.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC DNA_pol_viral_C PF00336.18 OAI99547.1 - 0.076 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Calcipressin PF04847.12 OAI99565.1 - 0.099 12.4 0.6 0.2 11.4 0.6 1.5 1 0 0 1 1 1 0 Calcipressin DDE_3 PF13358.6 OAI99577.1 - 1.3e-31 109.4 0.0 1.9e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAI99577.1 - 0.0047 17.5 0.0 0.026 15.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAI99577.1 - 0.021 14.5 0.1 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.11 OAI99577.1 - 0.066 12.2 0.0 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain ABC_tran PF00005.27 OAI99624.1 - 1.6e-16 61.1 0.0 7.6e-16 58.9 0.0 2.0 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAI99624.1 - 7.7e-11 42.3 1.0 0.00026 20.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAI99624.1 - 0.00048 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAI99624.1 - 0.0055 16.3 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 OAI99624.1 - 0.0059 16.1 0.2 2.2 7.7 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 OAI99624.1 - 0.0079 16.4 0.1 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 OAI99624.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OAI99624.1 - 0.017 15.2 0.1 0.04 14.0 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAI99624.1 - 0.03 14.7 0.1 0.055 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 OAI99624.1 - 0.04 13.4 0.1 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_23 PF13476.6 OAI99624.1 - 0.047 14.2 0.0 0.087 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAI99624.1 - 0.055 13.2 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 OAI99624.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 OAI99624.1 - 0.079 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAI99624.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 OAI99624.1 - 0.1 12.3 0.2 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 OAI99624.1 - 0.18 12.2 0.2 1.9 8.9 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dus PF01207.17 OAI99635.1 - 2.3e-62 210.9 0.0 1.8e-53 181.7 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TPR_1 PF00515.28 OAI99635.1 - 2.3e-05 24.0 3.6 1.6 8.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAI99635.1 - 0.0016 18.1 0.0 0.064 13.0 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 OAI99635.1 - 0.0024 18.5 3.3 2.8 8.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAI99635.1 - 0.014 15.5 6.0 0.96 9.7 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat NMO PF03060.15 OAI99635.1 - 0.025 14.0 0.0 0.062 12.7 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase CLIP1_ZNF PF16641.5 OAI99667.1 - 0.02 14.8 0.6 0.041 13.8 0.6 1.6 1 0 0 1 1 1 0 CLIP1 zinc knuckle Complex1_LYR PF05347.15 OAI99667.1 - 0.02 14.9 2.1 0.041 13.9 2.1 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Activator-TraM PF11657.8 OAI99667.1 - 0.65 9.8 6.9 1.4 8.8 6.9 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM DUF4192 PF13830.6 OAI99667.1 - 0.86 9.6 9.5 1.5 8.8 9.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) ThylakoidFormat PF11264.8 OAI99667.1 - 1.1 8.9 4.8 1.6 8.3 4.8 1.2 1 0 0 1 1 1 0 Thylakoid formation protein DUF4407 PF14362.6 OAI99667.1 - 1.5 8.1 8.7 2 7.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pinin_SDK_memA PF04696.13 OAI99667.1 - 3.3 7.8 10.6 5.3 7.1 10.6 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CDC27 PF09507.10 OAI99676.1 - 0.1 12.0 2.8 0.12 11.8 2.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Asp PF00026.23 OAI99677.1 - 2.6e-23 82.9 6.7 1.2e-22 80.8 6.7 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAI99677.1 - 0.0001 22.6 4.0 0.00023 21.4 0.2 2.6 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAI99677.1 - 0.14 12.8 1.4 0.32 11.7 0.3 2.2 2 0 0 2 2 2 0 Aspartyl protease Gly_kinase PF02595.15 OAI99690.1 - 0.047 12.7 0.4 0.068 12.2 0.4 1.1 1 0 0 1 1 1 0 Glycerate kinase family Polysacc_deac_1 PF01522.21 OAI99691.1 - 1.2e-22 80.1 0.0 2.7e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3292 PF11696.8 OAI99702.1 - 1.2e-13 50.3 4.7 4.2e-07 28.7 0.3 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3292) PRT_C PF08372.10 OAI99702.1 - 0.00064 19.5 3.2 0.0018 18.0 1.0 2.3 1 1 1 2 2 2 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.17 OAI99702.1 - 0.0037 17.3 2.8 0.052 13.5 1.3 2.2 2 0 0 2 2 2 1 Reticulon GRAM PF02893.20 OAI99702.1 - 0.0053 16.6 0.1 0.0092 15.9 0.1 1.3 1 0 0 1 1 1 1 GRAM domain DUF639 PF04842.12 OAI99702.1 - 0.75 9.2 3.4 5.4 6.4 0.2 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) DDE_Tnp_4 PF13359.6 OAI99722.1 - 4.4e-14 52.5 0.1 1.3e-13 50.9 0.0 1.8 3 0 0 3 3 3 1 DDE superfamily endonuclease NDC10_II PF16787.5 OAI99734.1 - 1.3e-53 182.1 0.0 1.8e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 ABC2_membrane_3 PF12698.7 OAI99734.1 - 0.012 14.7 0.1 0.017 14.3 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein UPRTase PF14681.6 OAI99749.1 - 1.4e-49 168.3 0.0 1.6e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAI99749.1 - 0.00073 19.1 0.0 0.00085 18.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Orthopox_A5L PF06193.11 OAI99750.1 - 0.21 11.0 0.6 0.35 10.3 0.6 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like EBV-NA1 PF02905.14 OAI99750.1 - 0.49 10.2 1.7 0.92 9.3 1.7 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Kei1 PF08552.11 OAI99785.1 - 0.36 10.7 0.2 0.39 10.6 0.2 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 NPR3 PF03666.13 OAI99785.1 - 1.6 7.4 8.3 1.7 7.3 8.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 OAI99785.1 - 5.1 6.4 13.3 5.4 6.3 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) LapA_dom PF06305.11 OAI99829.1 - 0.19 11.6 0.5 0.35 10.7 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF1180 PF06679.12 OAI99829.1 - 9.3 6.6 12.0 0.28 11.6 4.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HSP70 PF00012.20 OAI99842.1 - 1.8e-69 234.5 0.6 2.1e-69 234.3 0.6 1.0 1 0 0 1 1 1 1 Hsp70 protein GCR1_C PF12550.8 OAI99858.1 - 6.2e-11 42.5 0.3 1.2e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 OAI99858.1 - 8.4e-11 41.5 0.2 1.2e-10 40.9 0.2 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 LCCL PF03815.19 OAI99870.1 - 1.1e-16 60.7 0.0 2.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 LCCL domain zf-BED PF02892.15 OAI99894.1 - 0.033 14.2 2.6 0.072 13.1 2.6 1.5 1 0 0 1 1 1 0 BED zinc finger PRCC PF10253.9 OAI99895.1 - 3.5 8.4 13.2 0.045 14.5 5.6 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting ELFV_dehydrog_N PF02812.18 OAI99898.1 - 3.3e-17 62.6 0.0 4.9e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.25 OAI99913.1 - 1e-50 172.6 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAI99913.1 - 5.7e-30 104.4 0.0 6.4e-29 101.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAI99913.1 - 4.4e-06 26.2 0.0 1.1e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Fumble PF03630.14 OAI99927.1 - 1.3e-121 405.9 0.0 3.6e-121 404.4 0.0 1.7 1 1 0 1 1 1 1 Fumble DNA_pol_phi PF04931.13 OAI99927.1 - 1.4 6.9 5.9 2.7 6.0 5.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Caskin-Pro-rich PF16907.5 OAI99946.1 - 2.1 8.9 9.0 2.5 8.7 9.0 1.2 1 0 0 1 1 1 0 Proline rich region of Caskin proteins AICARFT_IMPCHas PF01808.18 OAI99961.1 - 0.0012 18.3 0.1 0.0015 18.1 0.1 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MetJ PF01340.20 OAI99978.1 - 0.093 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Met Apo-repressor, MetJ RT_RNaseH PF17917.1 OAI99994.1 - 2.7e-16 59.8 0.0 1.5e-15 57.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAI99994.1 - 1.3e-15 57.2 0.0 2.3e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAI99994.1 - 1.5e-14 53.8 0.3 3.1e-14 52.8 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAI99994.1 - 3.4e-08 33.7 0.0 1.1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAI99994.1 - 5.7e-08 32.6 0.0 9.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YjbT PF17089.5 OAI99994.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein family E1-E2_ATPase PF00122.20 OAJ00001.1 - 1.3e-38 132.3 6.2 2.2e-38 131.6 3.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 OAJ00001.1 - 2.6e-15 55.9 0.0 4.9e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2157 PF09925.9 OAJ00001.1 - 0.0055 16.5 3.1 0.14 12.0 0.4 3.2 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) Hydrolase PF00702.26 OAJ00001.1 - 0.076 13.3 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 OAJ00001.1 - 0.084 13.3 5.8 0.37 11.3 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MARVEL PF01284.23 OAJ00001.1 - 0.14 12.2 4.9 0.083 12.9 0.5 2.3 2 0 0 2 2 2 0 Membrane-associating domain DUF4149 PF13664.6 OAJ00001.1 - 0.21 11.9 3.0 5.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Frag1 PF10277.9 OAJ00001.1 - 1.1 8.8 7.8 1.1 8.8 4.2 2.3 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family YhhN PF07947.14 OAJ00001.1 - 3.5 7.2 9.4 0.1 12.2 1.1 2.1 2 0 0 2 2 2 0 YhhN family cNMP_binding PF00027.29 OAJ00043.1 - 2.1e-37 127.1 0.1 5.6e-19 68.0 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 OAJ00043.1 - 2.2e-12 46.4 0.2 4.1e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Spt20 PF12090.8 OAJ00043.1 - 0.032 13.8 3.2 0.049 13.2 3.2 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 OAJ00043.1 - 6 7.0 10.0 15 5.8 10.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 OAJ00061.1 - 0.00082 18.8 0.0 0.00087 18.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Rrn6 PF10214.9 OAJ00062.1 - 0.0087 14.6 15.7 0.011 14.3 15.7 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor AF-4 PF05110.13 OAJ00062.1 - 0.011 13.9 20.5 0.014 13.6 20.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 OAJ00062.1 - 0.43 9.1 12.5 0.55 8.7 12.5 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 OAJ00062.1 - 1.7 7.4 6.5 1.8 7.2 6.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 OAJ00062.1 - 3.1 6.5 15.2 4.1 6.2 15.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5126 PF17166.4 OAJ00075.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) LIP PF03583.14 OAJ00093.1 - 8.9e-40 136.8 0.2 1.2e-37 129.9 0.2 2.0 1 1 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ00093.1 - 0.0003 20.1 0.3 0.026 13.8 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ00093.1 - 0.085 12.5 0.4 0.66 9.6 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ00093.1 - 0.14 11.6 0.7 1.7 8.0 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family F-box-like PF12937.7 OAJ00111.1 - 0.0015 18.4 0.5 0.066 13.1 0.2 2.8 2 0 0 2 2 2 1 F-box-like KAR9 PF08580.10 OAJ00127.1 - 1 7.8 16.4 1.3 7.5 16.4 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ndc1_Nup PF09531.10 OAJ00127.1 - 5 5.7 8.3 7.5 5.1 8.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ParA PF10609.9 OAJ00128.1 - 1.2e-82 277.0 0.0 3.4e-81 272.3 0.0 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ00128.1 - 4.1e-06 26.9 0.6 4.5e-05 23.5 0.9 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 OAJ00128.1 - 0.00058 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 OAJ00128.1 - 0.0006 19.8 0.0 0.023 14.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OAJ00128.1 - 0.00081 18.7 2.0 0.0027 16.9 0.4 2.3 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 OAJ00128.1 - 0.01 15.6 0.1 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ00128.1 - 0.016 15.6 0.1 0.036 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain CBP_BcsQ PF06564.12 OAJ00128.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 OAJ00128.1 - 0.026 14.4 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 OAJ00128.1 - 0.17 12.3 0.0 0.53 10.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase RWD PF05773.22 OAJ00129.1 - 2.1e-07 31.2 0.0 3.1e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 RWD domain zf-CCHC PF00098.23 OAJ00145.1 - 1.7e-31 106.9 53.3 8.6e-08 31.9 1.0 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ00145.1 - 3e-07 30.0 37.7 0.016 15.0 0.5 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ00145.1 - 5.7e-07 29.4 33.9 0.0094 15.9 0.3 6.1 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ00145.1 - 4.1e-06 26.4 35.0 0.042 13.6 1.3 6.1 5 1 1 6 6 6 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OAJ00145.1 - 0.077 12.8 52.9 0.25 11.2 4.4 6.4 6 0 0 6 6 6 0 Zinc knuckle Mu-like_Com PF10122.9 OAJ00145.1 - 0.16 11.5 0.1 0.16 11.5 0.1 5.0 5 1 0 5 5 5 0 Mu-like prophage protein Com Abhydrolase_6 PF12697.7 OAJ00146.1 - 2.1e-05 25.2 3.8 2.1e-05 25.2 3.8 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family TBK1_ULD PF18396.1 OAJ00146.1 - 0.0028 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Methyltransf_10 PF05971.12 OAJ00153.1 - 1.1e-51 176.0 0.0 5.3e-31 108.1 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase Methyltransf_31 PF13847.6 OAJ00153.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mod_r PF07200.13 OAJ00154.1 - 1.3e-19 70.7 5.7 4.1e-19 69.1 5.7 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Herpes_UL14 PF03580.14 OAJ00154.1 - 0.0036 17.6 1.6 0.0053 17.0 0.6 1.8 2 0 0 2 2 2 1 Herpesvirus UL14-like protein Glyco_H_20C_C PF18088.1 OAJ00154.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.5 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain JIP_LZII PF16471.5 OAJ00154.1 - 0.039 14.1 0.7 0.09 13.0 0.7 1.5 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ATG16 PF08614.11 OAJ00154.1 - 0.063 13.5 8.7 0.1 12.8 8.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4735 PF15882.5 OAJ00154.1 - 0.18 11.3 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4735) OPA3 PF07047.12 OAJ00156.1 - 5.3e-23 81.2 0.7 1.1e-22 80.1 0.7 1.6 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Histone_HNS PF00816.21 OAJ00156.1 - 0.057 14.3 5.7 0.21 12.4 0.9 2.3 2 0 0 2 2 2 0 H-NS histone family Spc7 PF08317.11 OAJ00187.1 - 0.0023 16.9 0.6 0.0023 16.9 0.6 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein WEMBL PF05701.11 OAJ00187.1 - 0.0048 15.7 8.5 0.0048 15.7 8.5 2.4 2 1 0 2 2 2 2 Weak chloroplast movement under blue light APG6_N PF17675.1 OAJ00187.1 - 0.0077 16.8 2.1 0.0077 16.8 2.1 4.2 2 2 2 4 4 4 1 Apg6 coiled-coil region FliS PF02561.14 OAJ00187.1 - 0.013 15.8 1.3 0.36 11.1 0.2 3.0 2 1 1 3 3 3 0 Flagellar protein FliS Filament PF00038.21 OAJ00187.1 - 0.11 12.1 24.0 0.38 10.3 7.6 3.9 2 2 2 4 4 4 0 Intermediate filament protein UPF0242 PF06785.11 OAJ00187.1 - 5.2 7.1 21.2 0.51 10.4 4.3 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Trimer_CC PF08954.11 OAJ00187.1 - 8.8 6.0 13.9 0.91 9.1 2.6 4.3 3 1 1 4 4 4 0 Trimerisation motif MFS_1 PF07690.16 OAJ00203.1 - 1.6e-35 122.7 42.1 1.6e-35 122.7 42.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ00203.1 - 7.4e-09 35.0 8.6 7.4e-09 35.0 8.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter GMC_oxred_C PF05199.13 OAJ00230.1 - 4.3e-29 101.9 0.1 9.2e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAJ00230.1 - 4e-26 92.1 0.0 6.9e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase CheZ PF04344.13 OAJ00231.1 - 0.00041 20.3 0.5 0.00055 19.9 0.5 1.1 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ Plasmid_RAQPRD PF09686.10 OAJ00231.1 - 0.017 15.3 1.6 0.026 14.7 1.6 1.3 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) BicD PF09730.9 OAJ00231.1 - 0.02 13.4 4.2 0.024 13.1 4.2 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D CRR7 PF12095.8 OAJ00231.1 - 0.026 15.0 2.3 0.041 14.3 1.1 1.8 1 1 1 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 Phage_GP20 PF06810.11 OAJ00231.1 - 0.038 13.8 4.5 0.051 13.4 4.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Cob_adeno_trans PF01923.18 OAJ00231.1 - 0.042 14.0 0.3 0.054 13.6 0.3 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Uso1_p115_C PF04871.13 OAJ00231.1 - 0.073 13.4 6.2 0.098 13.0 6.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 OAJ00231.1 - 0.16 12.6 7.8 0.22 12.2 7.8 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5344 PF17279.2 OAJ00231.1 - 0.19 12.4 5.3 0.28 11.8 5.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5344) FlaC_arch PF05377.11 OAJ00231.1 - 0.26 11.7 1.9 6.2 7.3 0.1 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Med9 PF07544.13 OAJ00231.1 - 0.4 10.8 7.1 0.96 9.6 7.1 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ATP-synt_DE PF00401.20 OAJ00231.1 - 2.9 8.2 5.0 5.4 7.4 5.0 1.5 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain F-box-like PF12937.7 OAJ00245.1 - 2.4e-14 52.9 1.1 3.7e-14 52.3 0.2 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ00245.1 - 3.7e-11 42.6 0.2 6.7e-11 41.8 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ00245.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 F-box DUF3337 PF11816.8 OAJ00245.1 - 0.094 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) NAD_binding_10 PF13460.6 OAJ00246.1 - 0.01 15.7 0.1 0.062 13.2 0.1 2.1 1 1 0 1 1 1 0 NAD(P)H-binding DUF4702 PF15774.5 OAJ00246.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) zf-C2HC5 PF06221.13 OAJ00261.1 - 7.9e-08 32.2 7.3 1.5e-07 31.3 7.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cactin_mid PF10312.9 OAJ00279.1 - 1.9e-64 217.1 4.9 1.9e-64 217.1 4.9 2.4 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 OAJ00279.1 - 2.3e-56 189.1 6.5 4.1e-56 188.3 6.5 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Bac_DnaA PF00308.18 OAJ00279.1 - 0.48 10.2 3.5 0.21 11.4 0.3 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Homeobox_KN PF05920.11 OAJ00314.1 - 3.5e-05 23.6 0.0 0.0001 22.1 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Ustilago_mating PF05722.12 OAJ00314.1 - 0.023 14.2 0.2 0.023 14.2 0.2 3.2 3 1 0 3 3 3 0 Ustilago B locus mating-type protein FMO-like PF00743.19 OAJ00335.1 - 2.1e-09 36.4 0.0 2.6e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 OAJ00335.1 - 1.4e-08 34.9 0.0 8.8e-08 32.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ00335.1 - 5.8e-08 32.3 0.1 0.024 13.9 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ00335.1 - 1.9e-07 30.7 0.0 0.062 12.5 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ00335.1 - 4.9e-07 29.9 0.5 0.0035 17.3 0.1 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ00335.1 - 4.3e-06 26.1 0.0 0.00049 19.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 OAJ00335.1 - 0.00016 21.4 0.1 0.0052 16.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 OAJ00335.1 - 0.054 12.6 0.2 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 OAJ00335.1 - 0.082 12.1 0.1 0.33 10.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family WD40 PF00400.32 OAJ00357.1 - 1.3e-13 51.2 4.5 1e-06 29.4 0.1 4.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ00357.1 - 0.011 16.0 0.0 0.25 11.7 0.0 2.4 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 OAJ00357.1 - 0.03 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 OAJ00357.1 - 0.048 12.3 0.1 2.5 6.6 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 MCM_bind PF09739.9 OAJ00358.1 - 1.9e-60 204.9 0.0 5e-48 163.9 0.0 4.6 3 1 0 3 3 3 3 Mini-chromosome maintenance replisome factor AAA_30 PF13604.6 OAJ00358.1 - 0.0061 16.3 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain TolA_bind_tri PF16331.5 OAJ00462.1 - 0.013 15.5 1.4 0.033 14.3 1.4 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Tim29 PF10171.9 OAJ00462.1 - 0.12 11.9 0.3 0.29 10.6 0.1 1.7 1 1 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Methyltransf_PK PF05891.12 OAJ00465.1 - 2.8e-49 167.6 0.0 1.1e-15 57.8 0.0 4.2 3 1 0 3 3 3 3 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 OAJ00465.1 - 0.00059 20.5 0.4 1.2 9.9 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ00465.1 - 0.00092 19.9 0.0 0.98 10.2 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ00465.1 - 0.0013 18.6 0.0 0.0076 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MRVI1 PF05781.12 OAJ00465.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 MRVI1 protein CDC45 PF02724.14 OAJ00465.1 - 0.28 9.4 4.7 1.7 6.8 0.3 2.1 2 0 0 2 2 2 0 CDC45-like protein LCD1 PF09798.9 OAJ00465.1 - 0.28 9.7 0.2 1.8 7.0 0.0 1.9 2 0 0 2 2 2 0 DNA damage checkpoint protein Spt20 PF12090.8 OAJ00465.1 - 1.1 8.9 3.9 1.6 8.3 3.9 1.2 1 0 0 1 1 1 0 Spt20 family Ring_hydroxyl_B PF00866.18 OAJ00482.1 - 0.023 14.7 0.1 0.13 12.3 0.0 2.1 3 0 0 3 3 3 0 Ring hydroxylating beta subunit DrsE_2 PF13686.6 OAJ00482.1 - 0.026 14.4 2.0 0.55 10.1 0.1 3.1 1 1 3 4 4 4 0 DsrE/DsrF/DrsH-like family Hexapep_loop PF18776.1 OAJ00482.1 - 0.42 10.3 2.1 29 4.4 0.2 2.9 2 0 0 2 2 2 0 Hexapeptide repeat including loop Stevor PF17410.2 OAJ00482.1 - 1.1 8.7 7.6 2 7.9 7.0 1.8 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame RT_RNaseH_2 PF17919.1 OAJ00497.1 - 5.2e-24 84.2 0.1 1.8e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ00497.1 - 3.7e-19 68.9 0.0 1.6e-12 47.6 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ00497.1 - 5.9e-16 58.3 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ00497.1 - 5e-10 39.6 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ00497.1 - 2.6e-07 30.4 0.0 6.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spc7 PF08317.11 OAJ00552.1 - 0.00065 18.7 0.4 0.00078 18.4 0.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DHR10 PF18595.1 OAJ00552.1 - 0.0035 17.4 2.1 0.005 16.9 2.1 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain HrpB7 PF09486.10 OAJ00552.1 - 0.0049 17.3 0.6 0.0067 16.8 0.6 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Lyase_aromatic PF00221.19 OAJ00553.1 - 0.015 13.9 0.2 1.8 7.2 0.0 2.0 1 1 1 2 2 2 0 Aromatic amino acid lyase Pet20 PF08692.10 OAJ00572.1 - 2 9.1 18.5 1.8e+04 -4.1 18.5 2.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 CRT10 PF08728.10 OAJ00572.1 - 5.5 5.0 19.8 9 4.3 19.8 1.3 1 0 0 1 1 1 0 CRT10 AF-4 PF05110.13 OAJ00572.1 - 5.9 4.8 51.0 8.1 4.4 51.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IBR PF01485.21 OAJ00573.1 - 3.5e-08 33.6 1.0 3.5e-08 33.6 1.0 3.4 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 OAJ00573.1 - 9.8e-08 32.3 0.0 2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 OAJ00573.1 - 1.4e-07 31.7 4.8 1.4e-07 31.7 4.8 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ00573.1 - 6.5e-06 26.1 5.3 6.5e-06 26.1 5.3 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ00573.1 - 5.6e-05 23.0 7.0 5.6e-05 23.0 7.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ00573.1 - 8.1e-05 22.4 12.2 0.00014 21.6 6.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ00573.1 - 0.00014 21.5 6.0 0.00031 20.4 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ00573.1 - 0.00061 19.6 4.5 0.00061 19.6 4.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ00573.1 - 0.0039 17.0 3.1 0.015 15.2 3.1 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ00573.1 - 0.022 14.9 1.2 0.022 14.9 1.2 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAJ00573.1 - 0.25 11.2 11.9 0.24 11.2 1.3 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 OAJ00573.1 - 3.4 7.6 13.6 0.26 11.2 6.4 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 GCR1_C PF12550.8 OAJ00590.1 - 0.1 12.9 0.2 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.25 OAJ00606.1 - 6.1e-21 75.0 0.0 1.7e-20 73.5 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ00606.1 - 2.5e-11 43.3 0.0 3.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ00606.1 - 5.2e-08 32.5 0.0 7.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 OAJ00606.1 - 0.043 12.8 0.1 0.064 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAJ00606.1 - 0.07 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2452 PF10504.9 OAJ00628.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) SPATA3 PF15662.5 OAJ00629.1 - 0.4 11.3 3.9 0.47 11.0 3.9 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Zn_protease PF05618.11 OAJ00630.1 - 0.028 14.3 0.1 0.032 14.1 0.1 1.1 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease DUF3099 PF11298.8 OAJ00630.1 - 0.42 10.8 1.7 4.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) MFS_1 PF07690.16 OAJ00654.1 - 2.2e-17 63.0 36.5 2.2e-17 63.0 36.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5367 PF17329.2 OAJ00654.1 - 0.002 18.2 3.3 0.002 18.2 3.3 2.8 3 0 0 3 3 3 1 Family of unknown function (DUF5367) Nterm_IS4 PF13006.7 OAJ00654.1 - 0.041 14.1 0.0 18 5.6 0.0 2.9 2 0 0 2 2 2 0 Insertion element 4 transposase N-terminal Sugar_tr PF00083.24 OAJ00654.1 - 1.1 8.0 28.4 0.0061 15.5 13.2 3.4 2 2 0 2 2 2 0 Sugar (and other) transporter ATP-synt_ab_Xtn PF16886.5 OAJ00655.1 - 0.088 12.7 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension PT PF04886.12 OAJ00655.1 - 0.73 9.4 6.5 1.1 8.9 0.9 2.2 1 1 1 2 2 2 0 PT repeat RVT_2 PF07727.14 OAJ00670.1 - 1.5e-69 234.3 0.0 2.1e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ00670.1 - 3.7e-16 59.4 0.0 7.6e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ00670.1 - 9.8e-05 22.1 0.2 0.01 15.6 0.0 3.3 3 0 0 3 3 3 1 Integrase core domain DUF4708 PF15813.5 OAJ00672.1 - 0.042 13.0 0.0 0.059 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) NARP1 PF12569.8 OAJ00710.1 - 0.032 13.2 1.6 0.037 12.9 1.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCPVI PF02993.14 OAJ00710.1 - 0.043 13.6 5.3 0.064 13.1 5.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Lin-8 PF03353.15 OAJ00710.1 - 0.045 13.3 6.3 0.054 13.1 6.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.12 OAJ00710.1 - 0.074 12.0 3.5 0.089 11.8 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) EIIBC-GUT_N PF03612.14 OAJ00710.1 - 0.37 10.5 2.4 0.7 9.6 2.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CCDC53 PF10152.9 OAJ00710.1 - 0.41 11.1 6.5 0.62 10.5 6.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 OAJ00710.1 - 0.48 9.1 4.2 0.53 9.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 OAJ00710.1 - 0.5 10.4 6.0 0.74 9.8 6.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Rrn6 PF10214.9 OAJ00710.1 - 0.8 8.1 15.2 0.99 7.8 15.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Het-C PF07217.11 OAJ00710.1 - 1 7.8 4.2 3.1 6.2 0.0 2.0 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C RR_TM4-6 PF06459.12 OAJ00710.1 - 1.4 8.7 6.2 2.3 8.0 6.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 OAJ00710.1 - 1.4 7.9 6.9 1.8 7.6 6.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 OAJ00710.1 - 1.6 8.3 16.5 2.3 7.8 16.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF3405 PF11885.8 OAJ00710.1 - 2.6 6.5 7.1 3.5 6.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Ndc1_Nup PF09531.10 OAJ00710.1 - 8.9 4.9 8.9 10 4.6 8.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HLH PF00010.26 OAJ00733.1 - 7.6e-05 22.6 0.0 0.0037 17.2 0.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2828 PF11443.8 OAJ00733.1 - 1.1 7.3 9.5 1.8 6.6 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spt20 PF12090.8 OAJ00733.1 - 1.1 8.8 43.1 0.58 9.7 5.0 2.3 2 0 0 2 2 2 0 Spt20 family SLC12 PF03522.15 OAJ00733.1 - 1.4 7.8 14.5 2.1 7.3 14.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MMR1 PF08505.10 OAJ00733.1 - 2.5 8.3 19.3 0.17 12.1 7.2 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein MAS20 PF02064.15 OAJ00733.1 - 3.1 7.9 15.2 3.6 7.7 0.3 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor RBM39linker PF15519.6 OAJ00733.1 - 8.8 7.5 13.9 5.5 8.1 6.7 2.9 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF4770 PF15994.5 OAJ00733.1 - 9.8 6.4 17.2 1.5 9.1 9.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Thioredoxin PF00085.20 OAJ00751.1 - 2.8e-35 120.4 0.0 1.3e-21 76.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 OAJ00751.1 - 3.1e-10 40.2 0.0 0.0074 16.2 0.0 3.6 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_3 PF13192.6 OAJ00751.1 - 1.8e-05 24.7 0.0 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.6 OAJ00751.1 - 0.002 18.5 0.1 0.72 10.3 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ00751.1 - 0.0045 16.9 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ00751.1 - 0.021 15.2 0.1 0.19 12.1 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin-like Redoxin PF08534.10 OAJ00751.1 - 0.083 12.6 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 Redoxin MSA-2c PF12238.8 OAJ00751.1 - 9.3 6.2 8.6 18 5.3 8.6 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c R3H PF01424.22 OAJ00776.1 - 1.5e-12 47.3 0.0 3.3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain Myb_DNA-bind_3 PF12776.7 OAJ00796.1 - 1.1e-14 55.1 0.6 3.5e-14 53.5 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ00796.1 - 0.0012 19.1 0.4 0.0029 17.9 0.4 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain SAP130_C PF16014.5 OAJ00796.1 - 3.5 6.6 10.3 12 4.9 5.9 2.1 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus CwfJ_C_2 PF04676.14 OAJ00812.1 - 2e-33 115.2 0.2 3.9e-33 114.3 0.2 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAJ00812.1 - 2.3e-26 92.1 0.0 3.1e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DDE_Tnp_4 PF13359.6 OAJ00835.1 - 1e-20 74.0 0.0 1.3e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ00835.1 - 8.3e-11 41.9 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ00835.1 - 2.1e-07 30.8 0.0 3.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ00835.1 - 0.11 12.8 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Transposase DDE domain Acetyltransf_2 PF00797.17 OAJ00835.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase Myb_DNA-bind_3 PF12776.7 OAJ00836.1 - 3.3e-15 56.8 5.7 3.5e-15 56.8 2.1 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ00836.1 - 6.3e-06 26.5 0.7 1.8e-05 25.0 0.7 1.9 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ00836.1 - 0.13 12.5 0.2 0.37 11.1 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain NAM-associated PF14303.6 OAJ00836.1 - 1.7 9.3 19.2 3.2 8.4 5.0 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 OAJ00836.1 - 5.3 6.6 23.3 0.068 12.8 6.5 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 OAJ00906.1 - 5e-50 168.8 0.0 5.8e-50 168.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ00906.1 - 0.0001 22.0 0.0 0.00022 20.9 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RGCC PF15151.6 OAJ00906.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Response gene to complement 32 protein family FYVE PF01363.21 OAJ00907.1 - 1.9e-19 69.6 0.2 3.7e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 OAJ00907.1 - 1.1e-09 37.9 0.8 1.1e-09 37.9 0.8 2.1 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Zn-C2H2_12 PF18112.1 OAJ00907.1 - 0.35 11.4 1.3 1.5 9.4 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain DZR PF12773.7 OAJ00907.1 - 2.5 8.2 4.8 1.7 8.8 1.9 2.0 2 0 0 2 2 2 0 Double zinc ribbon DDE_Tnp_4 PF13359.6 OAJ00928.1 - 1.3e-21 76.9 0.0 1.6e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ00928.1 - 6.3e-06 26.0 0.0 8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain ACC_epsilon PF13822.6 OAJ00929.1 - 9.7 7.0 8.5 34 5.2 5.8 3.0 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit U3snoRNP10 PF12397.8 OAJ00991.1 - 0.0011 19.3 0.1 0.0027 18.1 0.1 1.7 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 10 HD_5 PF13487.6 OAJ00991.1 - 0.016 15.5 0.1 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 HD domain RVT_1 PF00078.27 OAJ01020.1 - 4.1e-24 85.3 0.0 7.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ01020.1 - 4.8e-14 52.2 0.1 9.3e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ01020.1 - 4.6e-11 43.0 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ01020.1 - 9.6e-10 38.7 0.0 7e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ01020.1 - 1.8e-05 24.7 0.0 5.4e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ01020.1 - 0.018 15.2 0.1 0.039 14.2 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger Sof1 PF04158.14 OAJ01043.1 - 3e-26 91.5 12.8 4.7e-26 90.9 12.8 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 OAJ01043.1 - 3.2e-25 87.9 4.7 3.8e-05 24.4 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ01043.1 - 2.6e-06 27.6 0.0 3.2 8.1 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DSBA PF01323.20 OAJ01044.1 - 0.018 14.8 0.2 0.043 13.6 0.2 1.6 1 0 0 1 1 1 0 DSBA-like thioredoxin domain SUIM_assoc PF16619.5 OAJ01044.1 - 0.46 10.6 12.5 1.2 9.3 0.0 3.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 OAJ01044.1 - 0.65 9.9 10.4 0.87 9.5 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pyr_redox_2 PF07992.14 OAJ01063.1 - 8.1e-49 166.4 0.1 1e-48 166.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ01063.1 - 1.9e-10 41.1 0.0 1.8e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ01063.1 - 0.022 14.3 2.6 20 4.6 0.0 3.7 4 1 1 5 5 5 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ01063.1 - 0.08 12.2 0.0 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BLM10_mid PF16507.5 OAJ01082.1 - 3e-158 527.8 0.0 4.1e-158 527.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region zf-C3HC4_3 PF13920.6 OAJ01107.1 - 0.27 11.1 3.5 0.51 10.2 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.28 OAJ01172.1 - 2.3e-09 37.3 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HECT PF00632.25 OAJ01173.1 - 3.5e-92 309.2 0.0 4.1e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AMP-binding PF00501.28 OAJ01192.1 - 1.9e-20 72.9 0.5 1.1e-18 67.1 0.5 2.5 2 1 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ01192.1 - 3.1e-12 46.2 0.0 6.5e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ01192.1 - 7.5e-08 32.1 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ01192.1 - 0.0047 16.9 0.0 0.024 14.6 0.0 2.2 1 1 0 1 1 1 1 KR domain PP-binding PF00550.25 OAJ01192.1 - 0.072 13.5 0.0 0.74 10.2 0.0 2.4 1 1 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 OAJ01192.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ran_BP1 PF00638.18 OAJ01194.1 - 5.2e-51 172.0 2.0 8.8e-51 171.3 2.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 OAJ01194.1 - 5.5e-06 26.3 1.0 3.1e-05 23.9 1.0 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 OAJ01194.1 - 0.00089 19.0 0.1 0.0011 18.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) VID27_PH PF17747.1 OAJ01194.1 - 0.0085 16.4 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain DUF4358 PF14270.6 OAJ01194.1 - 0.2 12.0 0.0 0.2 12.0 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) ASFV_J13L PF05568.11 OAJ01194.1 - 1.1 9.0 5.1 1.7 8.4 5.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein APG12 PF04110.13 OAJ01195.1 - 6.9e-32 109.7 0.0 8.8e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 OAJ01195.1 - 0.0049 17.0 0.0 0.0057 16.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 OAJ01195.1 - 0.099 12.7 0.0 0.88 9.7 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fold modifier 1 protein FliP PF00813.20 OAJ01195.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 FliP family rve PF00665.26 OAJ01216.1 - 1.3e-17 64.1 0.0 2.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 OAJ01216.1 - 4.2e-06 26.6 2.4 1.2e-05 25.2 2.4 1.8 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.6 OAJ01216.1 - 1.5e-05 24.8 0.1 3.5e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ01216.1 - 0.0037 17.0 0.4 0.036 13.9 0.4 2.5 1 1 0 1 1 1 1 Integrase core domain KH_1 PF00013.29 OAJ01237.1 - 9.8e-09 34.9 0.0 0.00013 21.7 0.0 2.6 2 0 0 2 2 2 2 KH domain Trp_repressor PF01371.19 OAJ01237.1 - 0.043 14.0 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 Trp repressor protein Presenilin PF01080.17 OAJ01258.1 - 0.7 8.6 2.6 0.79 8.4 2.6 1.0 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 OAJ01258.1 - 5.4 5.2 10.7 5.6 5.1 10.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Asp PF00026.23 OAJ01299.1 - 2.7e-42 145.3 0.0 1.3e-41 143.1 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ01299.1 - 9e-05 22.8 3.4 0.0098 16.1 1.0 2.3 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ01299.1 - 0.0006 20.4 0.5 0.043 14.5 0.2 2.5 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ01299.1 - 0.021 15.4 0.4 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3712 PF12505.8 OAJ01299.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3712) Acyl-CoA_dh_1 PF00441.24 OAJ01323.1 - 4.7e-48 163.2 5.6 4.7e-48 163.2 5.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ01323.1 - 3.3e-28 97.7 0.2 9.2e-28 96.3 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ01323.1 - 7.5e-25 87.8 0.2 7.5e-25 87.8 0.2 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ01323.1 - 5.3e-19 68.8 6.0 5.3e-19 68.8 6.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 OAJ01323.1 - 2.5e-05 24.1 0.1 0.00011 22.0 0.1 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Ras PF00071.22 OAJ01351.1 - 1.2e-56 190.8 0.0 1.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ01351.1 - 5.6e-35 120.2 0.1 7.8e-35 119.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ01351.1 - 1.3e-16 60.6 0.0 1.1e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ01351.1 - 6.9e-06 25.6 0.0 9.1e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ01351.1 - 0.00015 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ01351.1 - 0.00027 21.0 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ01351.1 - 0.0026 18.1 0.3 0.0051 17.2 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ01351.1 - 0.057 13.3 0.0 10 6.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase ATP-synt_10 PF05176.14 OAJ01352.1 - 1.5e-45 155.5 0.0 2.3e-30 105.7 0.0 2.1 2 0 0 2 2 2 2 ATP10 protein CKS PF01111.19 OAJ01353.1 - 1.3e-35 121.5 0.1 1.7e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Lipase_3 PF01764.25 OAJ01375.1 - 1e-16 61.1 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ01375.1 - 0.0088 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ01375.1 - 0.019 15.6 0.9 0.019 15.6 0.9 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ01375.1 - 0.033 14.0 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_45 PF02015.16 OAJ01376.1 - 5.7e-22 78.7 0.6 6.7e-22 78.4 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Phage_holin_2_1 PF04971.12 OAJ01401.1 - 0.0068 16.4 0.1 0.0068 16.4 0.1 1.6 2 0 0 2 2 2 1 Bacteriophage P21 holin S DUF202 PF02656.15 OAJ01401.1 - 0.16 12.4 2.5 0.44 11.0 2.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) FA_hydroxylase PF04116.13 OAJ01427.1 - 9.4e-20 71.3 9.1 9.4e-20 71.3 9.1 2.4 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily MULE PF10551.9 OAJ01444.1 - 2.9e-08 34.0 0.1 8.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ01444.1 - 0.00015 20.7 0.2 0.00031 19.7 0.1 1.3 1 1 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 OAJ01444.1 - 0.043 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Transposase Dynamitin PF04912.14 OAJ01470.1 - 0.01 15.2 0.9 0.018 14.4 0.9 1.4 1 0 0 1 1 1 1 Dynamitin zf-CCHC PF00098.23 OAJ01470.1 - 0.088 12.9 5.4 0.17 12.1 5.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Thaumatin PF00314.17 OAJ01494.1 - 1.5e-17 64.0 3.6 2.4e-17 63.3 3.0 1.5 1 1 1 2 2 2 2 Thaumatin family FAD_binding_4 PF01565.23 OAJ01515.1 - 1.9e-26 92.5 1.7 3.4e-26 91.7 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ01515.1 - 3.1e-06 27.2 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like REV PF00424.18 OAJ01515.1 - 0.13 12.3 0.6 0.31 11.1 0.6 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Dicty_REP PF05086.12 OAJ01516.1 - 9.4 4.1 4.8 12 3.7 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Fringe PF02434.16 OAJ01536.1 - 2.6e-05 23.8 0.7 0.00025 20.6 0.5 2.3 2 1 0 2 2 2 1 Fringe-like Phage_integrase PF00589.22 OAJ01537.1 - 0.0053 16.6 0.1 0.0075 16.1 0.1 1.2 1 0 0 1 1 1 1 Phage integrase family Cu-oxidase_3 PF07732.15 OAJ01562.1 - 1.3e-26 93.0 3.5 1.3e-25 89.7 0.2 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 OAJ01562.1 - 3.8e-15 56.3 0.0 8.1e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ01562.1 - 6.7e-15 55.0 8.7 6.3e-11 42.2 2.6 3.6 2 2 0 2 2 2 2 Multicopper oxidase Histone PF00125.24 OAJ01587.1 - 2.8e-29 102.1 0.4 3.1e-29 102.0 0.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OAJ01587.1 - 0.0048 17.5 1.4 0.006 17.2 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain BON PF04972.17 OAJ01587.1 - 0.044 14.1 0.1 0.097 13.0 0.1 1.6 1 0 0 1 1 1 0 BON domain zf-BED PF02892.15 OAJ01588.1 - 0.0048 16.9 0.3 0.013 15.5 0.3 1.8 1 0 0 1 1 1 1 BED zinc finger CH PF00307.31 OAJ01608.1 - 7e-78 257.9 0.0 1.2e-19 70.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 OAJ01608.1 - 1.3e-05 24.9 0.0 0.66 9.9 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 OAJ01608.1 - 2.9e-05 24.4 0.3 2.9e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 OAJ01608.1 - 0.11 12.6 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein EF-hand_6 PF13405.6 OAJ01608.1 - 0.61 10.2 3.1 15 5.9 0.1 3.9 4 0 0 4 4 4 0 EF-hand domain CDK5_activator PF03261.15 OAJ01647.1 - 0.21 11.1 4.5 0.3 10.6 4.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Antifungal_pept PF11410.8 OAJ01648.1 - 0.0034 17.3 12.0 0.01 15.7 1.4 2.6 2 1 0 2 2 2 2 Antifungal peptide ADAM_CR_2 PF17771.1 OAJ01648.1 - 0.08 13.5 16.5 0.39 11.3 6.7 3.1 2 1 0 2 2 2 0 ADAM cysteine-rich domain Omega-toxin PF06357.11 OAJ01648.1 - 1.5 8.7 14.1 3.2 7.6 4.9 2.5 1 1 1 2 2 2 0 Omega-atracotoxin EB PF01683.18 OAJ01648.1 - 2.8 8.3 10.4 9.5 6.6 10.5 1.9 1 1 0 1 1 1 0 EB module rve PF00665.26 OAJ01673.1 - 9.3e-05 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Trp_repressor PF01371.19 OAJ01673.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Trp repressor protein WTX PF09422.10 OAJ01674.1 - 0.23 10.5 4.4 0.23 10.5 4.4 1.1 1 0 0 1 1 1 0 WTX protein Metal_resist PF13801.6 OAJ01674.1 - 0.38 11.0 7.1 0.64 10.2 7.1 1.4 1 0 0 1 1 1 0 Heavy-metal resistance T3SSipB PF16535.5 OAJ01700.1 - 0.0085 16.6 1.7 0.026 15.0 1.7 1.8 1 0 0 1 1 1 1 Type III cell invasion protein SipB KxDL PF10241.9 OAJ01700.1 - 0.13 12.6 5.4 0.3 11.4 5.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein zf-C4H2 PF10146.9 OAJ01701.1 - 0.014 15.7 0.5 0.032 14.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein SKA1 PF07160.12 OAJ01701.1 - 0.056 13.3 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CCDC53 PF10152.9 OAJ01701.1 - 0.53 10.7 3.4 5.3 7.4 3.4 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex COesterase PF00135.28 OAJ01744.1 - 3e-56 191.4 0.0 8e-56 190.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ01744.1 - 6.9e-11 42.4 0.3 7.1e-10 39.1 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAJ01744.1 - 0.0013 18.2 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase DcpS_C PF11969.8 OAJ01744.1 - 0.0024 18.3 0.0 0.0044 17.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ01744.1 - 0.058 14.1 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 HIT domain Esterase PF00756.20 OAJ01744.1 - 0.069 12.8 0.2 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Putative esterase Collagen PF01391.18 OAJ01769.1 - 4.6e-15 55.1 60.5 2.5e-09 36.7 28.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) YrhK PF14145.6 OAJ01769.1 - 0.0099 15.7 0.2 13 5.8 0.0 3.3 3 0 0 3 3 3 2 YrhK-like protein FSA_C PF10479.9 OAJ01769.1 - 3.8 5.5 8.5 5.8 4.9 8.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NUDE_C PF04880.13 OAJ01769.1 - 8.9 6.7 8.4 29 5.1 8.4 1.8 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PIF1 PF05970.14 OAJ01787.1 - 3.4e-53 181.1 0.0 4.5e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ01787.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ01787.1 - 0.0022 18.3 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ01787.1 - 0.14 12.6 1.9 0.19 12.1 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain Brr6_like_C_C PF10104.9 OAJ01821.1 - 0.045 13.5 2.2 0.079 12.7 1.8 1.6 1 1 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain PetN PF03742.14 OAJ01821.1 - 0.079 12.8 0.3 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 PetN Radical_SAM PF04055.21 OAJ01821.1 - 0.18 12.1 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily Tachystatin_B PF11478.8 OAJ01894.1 - 0.36 10.8 4.5 0.96 9.4 4.5 1.7 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B RTC4 PF14474.6 OAJ01916.1 - 0.0096 16.1 0.0 0.023 14.8 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain ATP-synt_D PF01813.17 OAJ01941.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Sec23_helical PF04815.15 OAJ01994.1 - 5.1e-24 84.1 0.7 8.2e-24 83.4 0.7 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 OAJ01994.1 - 1.1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat DUF3429 PF11911.8 OAJ01995.1 - 3.8e-39 134.3 16.6 5.8e-39 133.7 16.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) RVT_1 PF00078.27 OAJ02022.1 - 1.5e-26 93.3 0.0 2.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ02022.1 - 4.4e-14 52.3 0.2 1.2e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 OAJ02022.1 - 1.8e-11 44.2 0.0 4.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ02022.1 - 3.2e-11 43.1 0.0 7.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ02022.1 - 0.00063 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ02023.1 - 5.8e-06 26.9 0.1 1e-05 26.1 0.1 1.5 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ02023.1 - 0.00059 20.3 0.0 0.0017 18.8 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ02023.1 - 0.043 14.1 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease DS PF01916.17 OAJ02026.1 - 9.2e-132 438.6 0.0 1.1e-131 438.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF1168 PF06658.12 OAJ02046.1 - 1.3e-39 135.1 12.1 1.3e-39 135.1 12.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) CENP-N PF05238.13 OAJ02046.1 - 0.097 12.0 5.2 0.11 11.7 5.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like PPL5 PF18168.1 OAJ02046.1 - 0.34 10.2 5.9 0.45 9.8 5.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF966 PF06136.13 OAJ02046.1 - 0.57 9.8 8.7 0.74 9.5 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 OAJ02046.1 - 0.6 8.8 2.3 0.82 8.4 2.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 OAJ02046.1 - 1.5 7.5 3.4 1.5 7.5 3.4 1.1 1 0 0 1 1 1 0 Presenilin TipE PF16972.5 OAJ02046.1 - 6.5 5.8 5.3 4.5 6.3 4.1 1.3 1 1 0 1 1 1 0 Na+ channel auxiliary subunit TipE THOC2_N PF16134.5 OAJ02046.1 - 7.2 5.1 6.5 10 4.6 6.5 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus RAMP4 PF06624.12 OAJ02047.1 - 4.8e-13 49.0 0.6 6.9e-13 48.5 0.6 1.3 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UQ_con PF00179.26 OAJ02048.1 - 4.6e-44 149.5 0.0 5.3e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TCRP1 PF14944.6 OAJ02048.1 - 0.14 12.1 0.4 5.7 6.8 0.3 2.0 1 1 1 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 Helicase_C PF00271.31 OAJ02078.1 - 3.8e-13 49.8 0.0 6.3e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ02078.1 - 0.0084 15.9 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase NOA36 PF06524.12 OAJ02078.1 - 0.24 10.7 3.6 38 3.5 5.9 2.1 2 0 0 2 2 2 0 NOA36 protein PBP1_TM PF14812.6 OAJ02078.1 - 1.8 9.0 7.5 5.3 7.5 7.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRCT_2 PF16589.5 OAJ02131.1 - 3.9e-09 36.8 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ02131.1 - 7.4e-08 32.7 0.3 1.1e-06 28.9 0.1 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ02131.1 - 8.9e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 OAJ02131.1 - 0.0011 18.9 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Endonuc_Holl PF10107.9 OAJ02131.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase adh_short PF00106.25 OAJ02132.1 - 2e-19 69.8 0.0 7.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ02132.1 - 9e-12 45.0 0.0 2.6e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ02132.1 - 3.2e-08 33.7 0.1 6.2e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ02132.1 - 0.073 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WW PF00397.26 OAJ02157.1 - 2.9e-09 36.8 1.4 0.00039 20.5 0.1 2.5 2 0 0 2 2 2 2 WW domain SprA-related PF12118.8 OAJ02189.1 - 0.0016 17.7 1.1 0.0019 17.4 1.1 1.0 1 0 0 1 1 1 1 SprA-related family PEHE PF15275.6 OAJ02189.1 - 0.057 14.0 3.5 0.066 13.8 3.5 1.1 1 0 0 1 1 1 0 PEHE domain PTPRCAP PF15713.5 OAJ02252.1 - 0.00041 20.7 5.7 0.00087 19.6 5.7 1.6 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 OAJ02252.1 - 0.00083 17.8 6.5 0.0011 17.4 6.5 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 OAJ02252.1 - 0.0012 19.0 10.1 0.002 18.3 10.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 OAJ02252.1 - 0.01 14.1 10.2 0.013 13.8 10.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ02252.1 - 0.013 14.9 11.4 0.019 14.4 11.4 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 OAJ02252.1 - 0.031 12.4 15.1 0.043 11.9 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ02252.1 - 0.033 13.9 8.9 0.059 13.1 8.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.13 OAJ02252.1 - 0.26 10.9 8.1 0.45 10.1 8.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM176 PF14851.6 OAJ02252.1 - 0.93 9.1 8.4 1.7 8.3 8.4 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 OAJ02252.1 - 1.5 8.8 7.1 2.8 7.9 7.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.11 OAJ02252.1 - 2 8.3 5.9 4.6 7.1 5.9 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4637 PF15470.6 OAJ02252.1 - 4.5 7.0 11.4 11 5.7 11.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PPV_E1_N PF00524.18 OAJ02252.1 - 5.9 7.3 14.4 9.5 6.7 11.6 2.4 2 1 0 2 2 2 0 E1 Protein, N terminal domain RRN3 PF05327.11 OAJ02252.1 - 9.8 4.6 9.0 14 4.1 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ldh_1_C PF02866.18 OAJ02287.1 - 8.9e-09 35.5 0.0 1.4e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_45 PF02015.16 OAJ02317.1 - 1e-47 162.8 3.9 1.2e-47 162.5 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 KASH PF10541.9 OAJ02317.1 - 0.21 11.9 1.4 0.23 11.8 0.0 1.8 2 0 0 2 2 2 0 Nuclear envelope localisation domain HsbA PF12296.8 OAJ02320.1 - 2.8e-17 63.3 14.2 5e-17 62.5 14.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Peptidase_S41_N PF11918.8 OAJ02320.1 - 0.027 14.7 2.2 0.084 13.1 1.5 2.0 1 1 1 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF1307 PF06998.11 OAJ02320.1 - 0.039 14.0 0.7 0.081 12.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1307) SNF2_N PF00176.23 OAJ02345.1 - 7.4e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Aa_trans PF01490.18 OAJ02374.1 - 8.4e-87 291.5 5.4 1.1e-86 291.2 5.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4218 PF13960.6 OAJ02395.1 - 0.038 13.6 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) RVT_1 PF00078.27 OAJ02424.1 - 1.1e-21 77.4 0.0 3.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ02424.1 - 8.4e-12 45.0 0.0 2.4e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ02424.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 OAJ02424.1 - 2 8.6 3.7 4.1 7.6 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Pterin_bind PF00809.22 OAJ02454.1 - 2.3e-58 197.8 1.7 1.4e-50 172.3 0.3 3.1 2 2 0 2 2 2 2 Pterin binding enzyme HPPK PF01288.20 OAJ02454.1 - 5.1e-28 97.8 0.0 1.4e-27 96.4 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 OAJ02454.1 - 1.5e-26 93.1 0.0 3.4e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase Asparaginase PF00710.20 OAJ02482.1 - 2.9e-57 193.3 0.0 3.3e-51 173.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 OAJ02482.1 - 8.8e-31 106.5 0.0 2e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 OAJ02482.1 - 1.8e-10 41.1 0.4 1.4e-09 38.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ02482.1 - 3.3e-10 40.4 0.0 7.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ02482.1 - 2.3e-08 33.7 0.3 0.00042 20.5 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 OAJ02482.1 - 9.1e-08 32.2 0.2 0.00029 21.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ02482.1 - 0.00047 20.5 1.3 0.43 11.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat DUF4542 PF15075.6 OAJ02570.1 - 0.052 13.9 0.1 0.1 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) RTA1 PF04479.13 OAJ02599.1 - 0.006 16.2 0.4 0.01 15.5 0.4 1.5 1 0 0 1 1 1 1 RTA1 like protein CENP-F_N PF10481.9 OAJ02625.1 - 1.1 8.8 4.9 4.4 6.9 4.6 2.0 1 1 1 2 2 2 0 Cenp-F N-terminal domain GATase_4 PF13230.6 OAJ02655.1 - 2.7e-17 62.6 0.0 1.3e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 OAJ02655.1 - 2.6e-09 37.4 0.0 6.3e-09 36.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Asp PF00026.23 OAJ02658.1 - 5.6e-37 127.8 0.0 2.6e-36 125.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ02658.1 - 2.2e-12 47.6 0.1 7.3e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RVT_1 PF00078.27 OAJ02689.1 - 8.1e-24 84.4 0.0 1.4e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ02689.1 - 1.3e-11 44.6 0.0 2.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ02689.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase dUTPase PF00692.19 OAJ02689.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 dUTPase Fringe PF02434.16 OAJ02712.1 - 7.2e-06 25.6 0.2 1.7e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 OAJ02712.1 - 0.08 12.7 0.0 1.6 8.5 0.0 2.2 1 1 0 1 1 1 0 Galactosyltransferase DUF4328 PF14219.6 OAJ02742.1 - 0.011 15.3 0.4 0.052 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) C1_2 PF03107.16 OAJ02742.1 - 1.4 9.3 5.5 2.7 8.4 5.5 1.5 1 0 0 1 1 1 0 C1 domain DDE_3 PF13358.6 OAJ02804.1 - 5.6e-31 107.3 0.0 1.2e-30 106.2 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OAJ02804.1 - 1.2e-06 28.6 0.2 4.1e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 Transposase HTH_33 PF13592.6 OAJ02804.1 - 0.00011 21.8 0.0 0.00033 20.2 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ02804.1 - 0.00013 22.5 0.0 0.00099 19.7 0.0 2.3 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 OAJ02804.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 OAJ02804.1 - 0.0099 15.3 0.1 0.039 13.4 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.12 OAJ02804.1 - 0.069 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 HTH domain HTH_29 PF13551.6 OAJ02804.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix MULE PF10551.9 OAJ02838.1 - 8.6e-08 32.5 0.0 1.9e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 MULE transposase domain RT_RNaseH_2 PF17919.1 OAJ02866.1 - 8e-20 70.7 0.3 2.3e-12 46.8 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ02866.1 - 7.7e-17 61.2 0.0 2e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ02866.1 - 8.3e-16 58.2 0.0 1.8e-10 41.0 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ02866.1 - 4.8e-13 49.3 0.0 2.2e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain p450 PF00067.22 OAJ02867.1 - 4.9e-15 55.2 0.0 6.1e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2236 PF09995.9 OAJ02897.1 - 2.6e-28 99.8 0.9 2.6e-28 99.8 0.9 2.2 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2236) Asp_protease_2 PF13650.6 OAJ02931.1 - 0.0012 19.4 0.0 0.0027 18.3 0.0 1.6 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ02931.1 - 0.0012 19.3 0.0 0.0082 16.7 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF4124 PF13511.6 OAJ02932.1 - 0.46 10.9 3.8 1.1 9.6 3.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DUF4813 PF16072.5 OAJ02955.1 - 0.71 9.5 31.7 0.84 9.2 31.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) ABC1 PF03109.16 OAJ03015.1 - 3.1e-25 88.7 0.0 5.6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Oxidored-like PF09791.9 OAJ03015.1 - 2.7e-17 62.1 2.0 7e-17 60.8 2.0 1.8 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 OAJ03015.1 - 0.48 10.4 3.2 1 9.4 3.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) KDZ PF18758.1 OAJ03018.1 - 4.7e-54 183.3 0.0 8.1e-54 182.6 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ03018.1 - 1.1e-06 28.8 0.0 3e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ03018.1 - 1.1e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases FA PF08736.11 OAJ03018.1 - 0.031 14.4 1.1 0.14 12.3 1.1 2.2 1 0 0 1 1 1 0 FERM adjacent (FA) CxC3 PF18804.1 OAJ03018.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases gag_pre-integrs PF13976.6 OAJ03047.1 - 6.2e-07 29.2 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF2451 PF10474.9 OAJ03047.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) RVT_2 PF07727.14 OAJ03050.1 - 1.8e-71 240.6 0.0 2.7e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ03050.1 - 4.5e-17 62.3 0.6 3.3e-16 59.6 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain rve_3 PF13683.6 OAJ03050.1 - 0.00012 21.8 0.1 0.00045 19.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain FHA PF00498.26 OAJ03075.1 - 0.0022 18.3 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 FHA domain RVT_1 PF00078.27 OAJ03193.1 - 8.3e-25 87.6 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ03193.1 - 1.6e-13 50.5 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ03193.1 - 5.9e-10 39.4 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ03193.1 - 0.00087 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ03193.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Pkinase PF00069.25 OAJ03223.1 - 6.4e-51 173.2 1.9 9.7e-51 172.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ03223.1 - 1.2e-19 70.6 0.0 1.2e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAJ03223.1 - 0.0038 17.2 0.1 0.0038 17.2 0.1 4.0 3 1 0 4 4 4 1 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 OAJ03256.1 - 2.9e-15 56.1 0.1 6.3e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ03256.1 - 7.9e-13 48.3 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ03256.1 - 1.3e-11 44.7 0.0 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ03256.1 - 5.4e-09 36.3 0.0 6.4e-08 32.8 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ03256.1 - 0.00014 21.4 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 OAJ03256.1 - 0.053 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger PAZ PF02170.22 OAJ03256.1 - 0.078 12.8 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 PAZ domain Ribosomal_S14 PF00253.21 OAJ03290.1 - 2.8e-21 75.0 0.2 4.3e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.11 OAJ03290.1 - 0.027 14.2 1.1 0.06 13.1 0.1 2.1 2 1 0 2 2 2 0 QLQ Ribosomal_L12 PF00542.19 OAJ03291.1 - 2.2e-20 72.7 8.3 9.1e-20 70.8 5.7 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 OAJ03291.1 - 3.9e-12 45.7 7.0 3.9e-12 45.7 7.0 4.5 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Med7 PF05983.11 OAJ03292.1 - 2.7e-41 141.8 1.0 6.8e-41 140.5 1.0 1.6 1 1 0 1 1 1 1 MED7 protein FapA PF03961.13 OAJ03292.1 - 0.031 12.9 0.2 0.043 12.4 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FdhE PF04216.12 OAJ03292.1 - 0.052 13.4 0.4 0.07 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation FlaC_arch PF05377.11 OAJ03292.1 - 0.079 13.4 0.4 6 7.3 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FliT PF05400.13 OAJ03292.1 - 0.62 10.9 6.6 1 10.2 5.5 1.8 2 0 0 2 2 2 0 Flagellar protein FliT tRNA-synt_1b PF00579.25 OAJ03372.1 - 1.2e-59 202.1 0.0 3.2e-59 200.7 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 OAJ03372.1 - 0.15 10.9 0.0 5 5.9 0.0 2.3 2 1 0 2 2 2 0 tRNA synthetases class I (K) MSP1_C PF07462.11 OAJ03372.1 - 2.3 6.8 6.3 4.3 5.9 6.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Rad60-SLD PF11976.8 OAJ03373.1 - 2.8e-22 78.3 0.2 3.3e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ03373.1 - 6e-12 45.1 0.0 6.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF1664 PF07889.12 OAJ03406.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.8 OAJ03407.1 - 0.052 13.5 0.5 0.13 12.3 0.3 1.7 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension RVT_2 PF07727.14 OAJ03442.1 - 1.2e-51 175.7 0.0 1.8e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ03442.1 - 1.2e-23 83.3 0.3 2.1e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ03442.1 - 6.7e-13 48.9 0.0 3.5e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain zf-CCHC PF00098.23 OAJ03442.1 - 8.4e-07 28.8 1.6 8.4e-07 28.8 1.6 1.8 2 0 0 2 2 2 1 Zinc knuckle gag_pre-integrs PF13976.6 OAJ03442.1 - 3e-06 27.0 0.0 6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ03442.1 - 0.005 16.6 0.2 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Prp31_C PF09785.9 OAJ03442.1 - 0.095 13.6 0.6 0.51 11.3 0.0 2.6 3 0 0 3 3 3 0 Prp31 C terminal domain 2OG-FeII_Oxy_3 PF13640.6 OAJ03444.1 - 3e-08 34.5 0.1 7.4e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAJ03444.1 - 0.082 13.6 0.0 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 OAJ03558.1 - 3.4e-19 69.0 7.0 3.4e-19 69.0 7.0 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Asp PF00026.23 OAJ03560.1 - 3.6e-114 381.4 0.2 4.3e-114 381.2 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ03560.1 - 3.9e-16 59.8 0.8 8.6e-14 52.2 0.8 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ03560.1 - 2.1e-05 24.4 0.0 0.0005 19.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 OAJ03560.1 - 0.00042 20.9 0.0 0.36 11.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ03560.1 - 0.0038 17.7 0.0 2.2 8.9 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease DUF3564 PF12087.8 OAJ03560.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) BDHCT_assoc PF16204.5 OAJ03560.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein DUF1768 PF08719.11 OAJ03563.1 - 1.4e-25 90.4 0.0 2.4e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PALP PF00291.25 OAJ03639.1 - 7.8e-62 209.3 1.1 1.7e-40 139.3 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme STE2 PF02116.15 OAJ03725.1 - 0.00017 21.0 1.3 0.00033 20.1 1.3 1.5 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PGG PF13962.6 OAJ03725.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function RNase_H PF00075.24 OAJ03759.1 - 6.9e-06 26.3 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Pkinase PF00069.25 OAJ03798.1 - 1.1e-41 143.0 0.0 1.3e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ03798.1 - 3.7e-26 92.0 0.0 4.5e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ03798.1 - 0.022 13.6 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAJ03798.1 - 0.028 14.3 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family ResIII PF04851.15 OAJ03800.1 - 8.7e-19 68.1 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ03800.1 - 5.8e-12 45.7 0.0 9.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ03800.1 - 4.1e-11 43.2 0.0 1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 OAJ03800.1 - 0.00034 21.0 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 OAJ03800.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 OAJ03800.1 - 0.0022 17.8 2.0 1.8 8.3 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ03800.1 - 0.003 17.9 0.0 0.007 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ03800.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RVT_2 PF07727.14 OAJ03835.1 - 1.2e-46 159.3 0.0 4.5e-43 147.6 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ03835.1 - 6.8e-17 61.8 0.0 3e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ03835.1 - 5.1e-05 23.0 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ03835.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ03836.1 - 1.4e-13 50.7 0.0 2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ03836.1 - 0.017 15.2 2.1 0.04 14.0 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 OAJ03836.1 - 0.018 14.5 0.2 0.043 13.3 0.2 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_2 PF13696.6 OAJ03836.1 - 0.033 14.0 4.0 0.11 12.4 3.4 2.1 2 0 0 2 2 2 0 Zinc knuckle SH3_9 PF14604.6 OAJ03874.1 - 3e-08 33.4 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ03874.1 - 2.4e-06 27.0 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TMEM51 PF15345.6 OAJ03874.1 - 0.00025 20.9 0.3 0.0006 19.7 0.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 Mucin15 PF15672.5 OAJ03874.1 - 0.007 15.9 1.1 0.007 15.9 1.1 2.2 2 0 0 2 2 2 1 Cell-membrane associated Mucin15 DDE_1 PF03184.19 OAJ03952.1 - 1.4e-19 70.5 1.2 1.2e-17 64.1 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease Ribosomal_60s PF00428.19 OAJ03952.1 - 0.04 14.5 4.8 0.089 13.4 2.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.6 OAJ03986.1 - 1e-23 84.3 0.6 4e-23 82.4 0.6 1.7 1 1 0 1 1 1 1 Helicase C-terminal domain AKAP2_C PF15304.6 OAJ03988.1 - 0.053 12.8 1.5 0.066 12.5 1.5 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus FLILHELTA PF10306.9 OAJ04021.1 - 1.7e-14 53.9 0.0 3.8e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 OAJ04021.1 - 0.0054 17.3 0.3 0.01 16.4 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Chorein_N PF12624.7 OAJ04023.1 - 6.5e-11 42.4 0.0 3.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Glyco_hydro_45 PF02015.16 OAJ04052.1 - 9.1e-15 55.1 3.7 2.1e-12 47.4 0.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 45 PAS_9 PF13426.7 OAJ04092.1 - 7.3e-18 64.7 0.0 2.2e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 OAJ04092.1 - 3.9e-07 30.1 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 OAJ04092.1 - 1e-05 25.7 0.0 0.0051 17.1 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 OAJ04092.1 - 1.5e-05 25.2 0.0 0.00015 21.9 0.0 2.6 3 0 0 3 3 3 1 PAS fold RGS PF00615.19 OAJ04092.1 - 1.9e-05 24.9 0.0 3.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_8 PF13188.7 OAJ04092.1 - 0.19 11.8 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 PAS domain Myb_DNA-bind_3 PF12776.7 OAJ04094.1 - 4.6e-20 72.4 0.8 7.5e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ04094.1 - 2e-08 34.5 1.2 4.9e-08 33.3 1.2 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ04094.1 - 0.04 14.2 0.6 0.1 12.8 0.6 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ04094.1 - 0.36 11.1 4.2 0.96 9.7 4.2 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain YfiO PF13525.6 OAJ04095.1 - 0.03 14.0 0.0 0.032 14.0 0.0 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein COesterase PF00135.28 OAJ04135.1 - 1.8e-96 324.1 0.0 2.2e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ04135.1 - 9.5e-10 38.7 1.5 5.8e-06 26.3 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ04135.1 - 0.011 15.2 0.2 0.02 14.3 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_60s PF00428.19 OAJ04172.1 - 2e-24 86.0 9.9 2e-24 86.0 9.9 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 OAJ04172.1 - 7.1e-23 80.6 0.1 1.8e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 OAJ04172.1 - 4.3e-21 74.7 0.1 8.5e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P DUF1816 PF08846.10 OAJ04243.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) DUF948 PF06103.11 OAJ04244.1 - 0.69 10.2 2.6 0.75 10.1 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Vma12 PF11712.8 OAJ04247.1 - 2.3e-29 102.2 0.5 3.6e-29 101.6 0.1 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TFIIIC_sub6 PF10419.9 OAJ04247.1 - 8.8e-12 44.7 0.0 1.8e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain PA_decarbox PF05870.11 OAJ04247.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Band_7 PF01145.25 OAJ04248.1 - 1.1e-23 84.2 6.4 1.1e-23 84.1 4.6 1.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 OAJ04248.1 - 0.0019 17.3 5.3 0.0036 16.4 5.3 1.4 1 1 0 1 1 1 1 SigmaW regulon antibacterial SRF-TF PF00319.18 OAJ04248.1 - 0.059 12.9 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2457 PF10446.9 OAJ04283.1 - 8.8 5.3 7.0 11 5.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AP3D1 PF06375.11 OAJ04324.1 - 0.0066 16.7 5.1 0.0066 16.7 5.1 3.6 4 0 0 4 4 4 1 AP-3 complex subunit delta-1 Med19 PF10278.9 OAJ04324.1 - 0.13 12.2 8.8 0.4 10.6 8.8 1.9 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Eapp_C PF10238.9 OAJ04324.1 - 0.2 11.7 1.1 1 9.4 1.1 2.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein PPL5 PF18168.1 OAJ04324.1 - 0.33 10.2 2.3 0.7 9.1 2.3 1.5 1 0 0 1 1 1 0 Prim-pol family 5 DNA_pol_phi PF04931.13 OAJ04324.1 - 0.63 8.1 4.0 1.1 7.2 4.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3464 PF11947.8 OAJ04324.1 - 0.65 9.7 2.5 4.2 7.1 2.5 2.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 NARP1 PF12569.8 OAJ04324.1 - 3.2 6.5 11.2 5.9 5.7 11.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Myb_DNA-bind_3 PF12776.7 OAJ04367.1 - 0.0071 17.3 0.0 0.0091 17.0 0.0 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain rve PF00665.26 OAJ04370.1 - 3.5e-10 40.1 0.0 4e-09 36.7 0.0 2.5 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ04370.1 - 2.5e-08 33.7 0.0 5.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Transcript_VP30 PF11507.8 OAJ04370.1 - 0.083 13.0 0.1 0.38 10.8 0.1 2.0 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RT_RNaseH PF17917.1 OAJ04372.1 - 7.1e-13 48.8 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ04372.1 - 2.9e-08 33.6 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase E3_binding PF02817.17 OAJ04412.1 - 2.6e-07 30.9 0.0 7.4e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.24 OAJ04413.1 - 1.1e-08 35.2 0.0 1.4e-06 28.4 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DDE_3 PF13358.6 OAJ04454.1 - 4.1e-14 52.6 0.0 6.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ04454.1 - 6.6e-06 26.6 0.1 6.6e-06 26.6 0.1 2.5 3 0 0 3 3 3 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ04454.1 - 0.00045 19.8 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 OAJ04454.1 - 0.0005 20.2 0.4 0.0014 18.8 0.4 1.8 1 0 0 1 1 1 1 Transposase Tankyrase_bdg_C PF15327.6 OAJ04454.1 - 0.067 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain DDE_1 PF03184.19 OAJ04454.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease Glyco_hydro_47 PF01532.20 OAJ04495.1 - 1e-130 436.7 0.0 1.8e-130 435.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 AIG1 PF04548.16 OAJ04497.1 - 0.052 12.9 0.1 0.2 11.0 0.0 1.8 1 1 1 2 2 2 0 AIG1 family Glyco_trans_4_4 PF13579.6 OAJ04561.1 - 8.1e-10 39.4 5.8 1.6e-09 38.4 3.5 2.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 OAJ04561.1 - 9.5e-08 32.6 0.0 4e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ04561.1 - 5.5e-05 23.2 1.9 0.00011 22.2 1.9 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ04561.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 OAJ04561.1 - 0.00086 19.7 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sporozoite_P67 PF05642.11 OAJ04561.1 - 7.7 4.5 20.8 0.11 10.6 12.1 2.3 1 1 0 2 2 2 0 Sporozoite P67 surface antigen Glutaredoxin PF00462.24 OAJ04655.1 - 6.9e-19 67.8 0.0 1.2e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAJ04655.1 - 1.9e-16 59.9 0.0 3.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ04655.1 - 5.6e-05 23.4 0.1 0.044 14.1 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ04655.1 - 0.00038 20.9 0.0 0.0024 18.3 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 OAJ04655.1 - 0.0023 17.8 0.0 0.011 15.6 0.0 2.0 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE DUF3246 PF11596.8 OAJ04655.1 - 0.01 15.3 1.8 0.015 14.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) OST3_OST6 PF04756.13 OAJ04655.1 - 0.062 12.6 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family RVT_1 PF00078.27 OAJ04695.1 - 2.7e-16 59.8 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP-alpha_N PF04086.13 OAJ04696.1 - 2.1 8.2 7.7 2.4 8.0 7.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 OAJ04696.1 - 6.1 5.3 9.5 6.2 5.2 9.5 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 OAJ04743.1 - 2.7e-42 144.9 0.0 4.1e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ04743.1 - 2.2e-26 92.7 0.0 3.1e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ04743.1 - 0.0075 15.6 0.0 0.12 11.7 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OAJ04743.1 - 0.015 15.2 1.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ04743.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RTC4 PF14474.6 OAJ04743.1 - 0.16 12.2 0.0 0.48 10.6 0.0 1.8 1 1 0 1 1 1 0 RTC4-like domain Transposase_21 PF02992.14 OAJ04785.1 - 3.1e-09 36.4 0.0 5.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 CDC45 PF02724.14 OAJ04785.1 - 1.5 7.0 5.7 2.2 6.4 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpv17_PMP22 PF04117.12 OAJ04834.1 - 1.6e-05 25.0 0.7 1.6e-05 25.0 0.7 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family TetR_C_20 PF17925.1 OAJ04834.1 - 0.00076 19.8 1.1 0.11 12.9 0.2 3.1 2 1 1 3 3 3 1 Tetracyclin repressor-like, C-terminal domain RRM_1 PF00076.22 OAJ04835.1 - 6.9e-18 64.2 0.0 1.2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ04835.1 - 1.2e-07 31.7 0.0 2.3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ04835.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAJ04835.1 - 0.039 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.19 OAJ04836.1 - 3.3e-35 120.8 4.6 4.3e-35 120.4 4.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ldr_toxin PF13940.6 OAJ04836.1 - 0.085 12.9 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system DUF349 PF03993.12 OAJ04882.1 - 0.01 16.1 6.5 0.014 15.7 6.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) bZIP_2 PF07716.15 OAJ04882.1 - 0.013 15.6 6.1 0.013 15.6 6.1 1.6 2 0 0 2 2 2 0 Basic region leucine zipper TetR_C_14 PF17754.1 OAJ04882.1 - 0.025 14.5 2.3 0.038 13.9 2.3 1.3 1 0 0 1 1 1 0 MftR C-terminal domain CDH1_2_SANT_HL1 PF18375.1 OAJ04882.1 - 0.1 13.3 2.6 2.3 8.9 0.1 2.1 1 1 1 2 2 2 0 CDH1/2 SANT-Helical linker 1 NYD-SP28_assoc PF14775.6 OAJ04882.1 - 0.14 12.3 2.6 0.25 11.5 2.6 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF3138 PF11336.8 OAJ04882.1 - 1.1 7.8 5.3 1.2 7.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 OAJ04929.1 - 1.9e-46 158.6 0.0 3.6e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ04929.1 - 5.2e-25 88.2 0.0 8.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ04929.1 - 0.0047 16.9 0.3 0.018 14.9 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ04929.1 - 0.04 12.9 0.2 0.077 11.9 0.2 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 OAJ04929.1 - 0.049 12.9 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 OAJ04929.1 - 0.15 11.6 0.2 6.3 6.4 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RNA_pol_Rpb6 PF01192.22 OAJ04930.1 - 6.7e-16 58.0 0.1 9.4e-16 57.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RVT_1 PF00078.27 OAJ04964.1 - 2.1e-21 76.4 0.0 4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ04964.1 - 2.3e-20 72.5 0.0 3.3e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ04964.1 - 1.7e-14 53.9 0.0 5.7e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ04964.1 - 2.7e-14 53.0 0.1 5e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ04964.1 - 2.1e-11 44.0 0.0 6.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ04964.1 - 0.01 16.1 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger LOH1CR12 PF10158.9 OAJ04966.1 - 0.11 12.6 1.7 0.29 11.2 1.0 2.2 2 0 0 2 2 2 0 Tumour suppressor protein HTH_1 PF00126.27 OAJ04966.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.8 4 0 0 4 4 4 0 Bacterial regulatory helix-turn-helix protein, lysR family MPS2 PF17060.5 OAJ04966.1 - 0.36 10.0 8.3 0.56 9.4 6.6 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 FlaC_arch PF05377.11 OAJ04966.1 - 2 8.9 16.4 1 9.8 0.1 5.7 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) CPSase_sm_chain PF00988.22 OAJ04967.1 - 1.5e-43 147.7 0.0 2.4e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 OAJ04967.1 - 1.2e-35 123.0 0.0 2.6e-35 121.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 OAJ04967.1 - 6.5e-06 26.1 0.2 9.4e-05 22.3 0.6 2.3 2 1 0 2 2 2 1 Peptidase C26 Ndc1_Nup PF09531.10 OAJ05013.1 - 0.066 11.9 5.6 0.077 11.7 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PHD PF00628.29 OAJ05013.1 - 0.07 13.0 10.2 0.21 11.5 10.2 1.8 1 0 0 1 1 1 0 PHD-finger rve PF00665.26 OAJ05014.1 - 0.0051 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain TruB_C_2 PF16198.5 OAJ05014.1 - 0.019 15.1 1.0 0.32 11.2 0.3 2.9 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain EHN PF06441.12 OAJ05066.1 - 2.7e-24 85.6 0.0 5.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ05066.1 - 2.9e-10 40.2 0.1 4.7e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ05066.1 - 0.00023 21.9 5.8 0.00034 21.3 5.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_2 PF07719.17 OAJ05069.1 - 6.5e-08 32.1 2.5 0.88 9.8 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ05069.1 - 3.2e-07 30.5 10.8 0.016 15.5 0.2 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ05069.1 - 1.4e-05 25.5 3.9 0.019 15.7 0.2 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ05069.1 - 1.7e-05 24.6 0.1 1.2 9.6 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ05069.1 - 0.00012 21.8 7.2 0.57 10.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ05069.1 - 0.00014 21.7 4.1 3.9 7.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ05069.1 - 0.00015 21.4 0.4 3.1 7.8 0.2 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ05069.1 - 0.0033 17.9 1.2 0.12 12.9 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ05069.1 - 0.13 12.9 6.8 0.072 13.7 1.9 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ05069.1 - 0.64 10.8 0.1 0.64 10.8 0.1 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ05069.1 - 0.71 10.1 2.7 42 4.5 0.0 3.5 5 0 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Helicase_C PF00271.31 OAJ05158.1 - 1.1e-09 38.6 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PUB_1 PF18486.1 OAJ05158.1 - 0.018 14.9 0.1 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain DEAD PF00270.29 OAJ05159.1 - 2.6e-06 27.3 0.1 3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase RT_RNaseH_2 PF17919.1 OAJ05251.1 - 2.6e-23 81.9 0.3 2.9e-15 56.1 0.1 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ05251.1 - 2.6e-23 82.7 0.0 5.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ05251.1 - 1e-16 60.8 0.1 2e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ05251.1 - 2.7e-16 59.7 0.0 3.2e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ05251.1 - 2.1e-09 37.6 0.0 4.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ05251.1 - 0.019 15.2 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Neurokinin_B PF03823.14 OAJ05301.1 - 0.11 12.6 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Neurokinin B TruD PF01142.18 OAJ05351.1 - 2.1e-48 165.2 0.0 1.3e-38 132.9 0.0 5.6 5 1 0 5 5 5 4 tRNA pseudouridine synthase D (TruD) WD40 PF00400.32 OAJ05353.1 - 5.6e-20 71.3 13.7 0.0014 19.4 0.1 6.7 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ05353.1 - 1.3e-07 31.8 0.1 0.29 11.5 0.0 4.6 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CLTH PF10607.9 OAJ05353.1 - 0.0011 18.9 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SGL PF08450.12 OAJ05353.1 - 0.0032 17.1 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 OAJ05353.1 - 0.83 9.7 4.3 69 3.6 0.1 4.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat CDO_I PF05995.12 OAJ05409.1 - 8.5e-05 21.9 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 OAJ05409.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 PCO_ADO SMP_2 PF10144.9 OAJ05409.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin ASF1_hist_chap PF04729.13 OAJ05455.1 - 2.7e-14 53.4 0.0 3.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone ICL PF00463.21 OAJ05456.1 - 6.9e-104 348.2 4.3 8.8e-49 166.4 0.0 3.7 1 1 2 3 3 3 3 Isocitrate lyase family Spem1 PF15670.5 OAJ05458.1 - 0.06 12.9 1.0 0.088 12.4 1.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 Helitron_like_N PF14214.6 OAJ05550.1 - 2e-31 109.7 0.0 3.2e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gelsolin PF00626.22 OAJ05553.1 - 3.2e-38 129.5 0.0 8.1e-15 54.5 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Questin_oxidase PF14027.6 OAJ05554.1 - 1.4e-80 271.4 1.6 1.7e-80 271.1 1.6 1.1 1 0 0 1 1 1 1 Questin oxidase-like Phage_int_SAM_1 PF02899.17 OAJ05587.1 - 0.036 14.4 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3123 PF11321.8 OAJ05588.1 - 4.6 7.9 8.2 4.1 8.1 6.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) DUF4366 PF14283.6 OAJ05589.1 - 0.035 14.1 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Rubredoxin_2 PF18073.1 OAJ05589.1 - 0.15 11.8 7.6 0.9 9.3 0.9 3.3 2 2 0 2 2 2 0 Rubredoxin metal binding domain Mito_carr PF00153.27 OAJ05638.1 - 8.2e-07 28.9 1.1 0.0045 16.9 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial carrier protein RT_RNaseH_2 PF17919.1 OAJ05641.1 - 6.3e-22 77.5 0.0 3.1e-14 52.8 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ05641.1 - 2.2e-16 60.1 0.0 3.5e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ05641.1 - 7.6e-16 58.0 0.3 1.7e-15 56.9 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ05641.1 - 8.4e-07 29.2 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_OrfB_IS605 PF12323.8 OAJ05698.1 - 4.4e-10 38.9 0.8 8.3e-10 38.0 0.8 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Aldo_ket_red PF00248.21 OAJ05757.1 - 1.6e-27 96.5 0.0 7.3e-27 94.3 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family NINJA_B PF16136.5 OAJ05758.1 - 0.0064 16.8 1.0 0.015 15.7 1.0 1.6 1 0 0 1 1 1 1 Putative nuclear localisation signal DUF3701 PF12482.8 OAJ05758.1 - 0.076 13.1 0.4 0.73 9.9 0.1 2.6 3 0 0 3 3 3 0 Phage integrase protein Dimer_Tnp_hAT PF05699.14 OAJ05761.1 - 8.1e-12 44.8 0.0 1.3e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PIF1 PF05970.14 OAJ05762.1 - 1.2e-35 123.4 0.0 3.6e-35 121.8 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ05762.1 - 0.00043 20.1 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RT_RNaseH_2 PF17919.1 OAJ05815.1 - 6.3e-30 103.2 0.0 1.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ05815.1 - 1.2e-21 77.0 0.0 2.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ05815.1 - 5.4e-19 68.6 0.0 1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ05815.1 - 0.0082 16.2 2.0 0.015 15.3 2.0 1.5 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 OAJ05866.1 - 4.2e-71 239.4 0.0 6.1e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ05866.1 - 3.4e-39 134.7 0.0 5.6e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ05866.1 - 2.5e-05 23.8 0.1 0.00014 21.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ05866.1 - 5e-05 22.9 0.4 0.0001 21.9 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 OAJ05866.1 - 0.0003 20.2 0.1 0.0033 16.8 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OAJ05866.1 - 0.0034 16.2 0.0 0.0069 15.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 OAJ05866.1 - 0.0042 16.7 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ05866.1 - 0.0077 16.2 0.2 0.058 13.3 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L32p PF01783.23 OAJ05870.1 - 0.033 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L32p protein family MPC PF03650.13 OAJ05931.1 - 9.8e-42 141.6 0.3 1.2e-41 141.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ILVD_EDD PF00920.21 OAJ05932.1 - 8.7e-200 664.7 0.0 1e-199 664.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family CTK3 PF12243.8 OAJ05985.1 - 1.1e-23 83.6 0.0 1.9e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 OAJ05985.1 - 1.3e-17 63.6 0.3 6.8e-11 42.2 0.1 2.5 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 C-terminus Pho88 PF10032.9 OAJ05986.1 - 1e-63 213.9 0.0 1.1e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) RabGAP-TBC PF00566.18 OAJ06048.1 - 8.1e-51 172.7 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RVT_1 PF00078.27 OAJ06098.1 - 5e-25 88.3 0.0 8.8e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ06098.1 - 2.5e-21 75.6 0.0 1.7e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ06098.1 - 4.8e-16 59.0 0.0 4.4e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ06098.1 - 3.4e-14 52.7 0.0 9.6e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ06098.1 - 4.5e-11 43.0 0.0 1.4e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ06098.1 - 2.7e-05 24.7 0.0 8.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ06098.1 - 0.0068 16.9 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ06098.1 - 0.025 14.9 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease dUTPase PF00692.19 OAJ06098.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 dUTPase PH PF00169.29 OAJ06162.1 - 1.5e-05 25.4 0.0 3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.11 OAJ06162.1 - 0.27 11.8 3.1 2.7 8.6 0.6 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CAF1A PF12253.8 OAJ06162.1 - 2.4 8.4 10.4 5.1 7.3 9.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A RVT_1 PF00078.27 OAJ06165.1 - 8.5e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ06165.1 - 7.2e-14 51.6 0.9 1.1e-13 51.0 0.1 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ06165.1 - 3e-13 49.7 0.0 5.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ06165.1 - 9.4e-05 22.6 0.0 0.00027 21.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ06165.1 - 0.0058 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ06165.1 - 0.025 14.8 0.1 0.054 13.7 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 OAJ06279.1 - 2.9e-25 89.1 0.0 4.8e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ06279.1 - 2e-21 75.9 0.0 1.5e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ06279.1 - 1.1e-14 54.6 0.0 4.3e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ06279.1 - 1.2e-13 51.0 0.0 2.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ06279.1 - 3e-12 46.8 0.0 8.9e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ06279.1 - 0.0021 18.6 0.1 0.022 15.4 0.0 2.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ06279.1 - 0.025 15.1 0.0 0.11 13.1 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Dimer_Tnp_hAT PF05699.14 OAJ06331.1 - 9.2e-18 63.8 0.6 2.6e-17 62.4 0.6 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ06331.1 - 0.00064 20.0 0.4 0.0025 18.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) DEAD PF00270.29 OAJ06334.1 - 1.9e-48 164.5 0.0 3.5e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ06334.1 - 1.4e-31 109.1 0.1 4.8e-31 107.4 0.0 1.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ06334.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Transferase PF02458.15 OAJ06335.1 - 7.4e-06 24.9 0.0 0.00059 18.6 0.0 2.8 2 1 0 2 2 2 2 Transferase family Aa_trans PF01490.18 OAJ06457.1 - 4.1e-57 193.7 8.3 1.8e-56 191.6 8.3 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ06457.1 - 0.00035 19.7 5.5 0.00035 19.7 5.5 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Nop14 PF04147.12 OAJ06457.1 - 0.58 8.3 9.9 0.78 7.9 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ06457.1 - 4.2 5.6 11.7 8.3 4.6 11.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Pinin_SDK_N PF04697.13 OAJ06523.1 - 4.9 7.8 10.4 88 3.7 10.4 2.0 1 1 0 1 1 1 0 pinin/SDK conserved region rve PF00665.26 OAJ06580.1 - 7.2e-18 64.9 0.0 1.4e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ06580.1 - 5.6e-14 52.0 0.0 1.4e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ06580.1 - 0.002 17.9 0.5 0.01 15.6 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain Helicase_C PF00271.31 OAJ06583.1 - 6.2e-10 39.4 0.0 1.3e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rve PF00665.26 OAJ06644.1 - 8.9e-13 48.5 0.0 1.5e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ06646.1 - 2.6e-19 69.7 0.0 4.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ06646.1 - 1.2e-13 50.9 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ06646.1 - 0.0016 18.7 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase UCH_1 PF13423.6 OAJ06705.1 - 4.7e-77 259.7 0.0 5.8e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 OAJ06705.1 - 5.6e-16 59.5 0.0 9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAJ06707.1 - 2.9e-13 49.9 0.0 6.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Macoilin PF09726.9 OAJ06707.1 - 0.72 8.3 8.0 0.036 12.7 0.2 2.0 2 0 0 2 2 2 0 Macoilin family SRP19 PF01922.17 OAJ06708.1 - 1.2e-23 83.9 0.1 2.9e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 SRP19 protein MCU PF04678.13 OAJ06708.1 - 0.49 10.5 1.2 3.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter EF-hand_1 PF00036.32 OAJ06776.1 - 2.9e-20 70.2 0.0 5e-06 25.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 OAJ06776.1 - 1.8e-19 68.0 0.3 5.2e-07 29.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 OAJ06776.1 - 1.1e-15 56.2 0.4 0.00093 18.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 OAJ06776.1 - 1.7e-15 57.2 0.0 1.7e-06 28.4 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 OAJ06776.1 - 4.4e-09 36.1 1.1 7.8e-05 22.5 0.0 3.5 3 2 1 4 4 4 3 EF-hand domain pair Nop PF01798.18 OAJ06847.1 - 4.7e-81 271.6 0.2 1e-80 270.6 0.2 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ06847.1 - 3.9e-11 43.2 0.0 1.3e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Nop16 PF09420.10 OAJ06848.1 - 3.9e-50 170.8 0.0 4.5e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Histone PF00125.24 OAJ06852.1 - 1.9e-18 67.1 0.0 2.8e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bac_rhamnosid PF05592.11 OAJ06852.1 - 0.17 11.9 0.2 0.27 11.2 0.2 1.4 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Dimer_Tnp_hAT PF05699.14 OAJ06853.1 - 2.5e-15 56.0 0.0 5.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ06853.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) LIP PF03583.14 OAJ06923.1 - 2e-25 89.7 2.9 3.1e-25 89.1 2.9 1.3 1 0 0 1 1 1 1 Secretory lipase GFA PF04828.14 OAJ06926.1 - 3.8e-07 30.4 0.2 1.9e-05 24.9 0.1 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Inhibitor_Mig-6 PF11555.8 OAJ07069.1 - 0.076 13.1 5.9 0.19 11.8 5.9 1.7 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 RT_RNaseH_2 PF17919.1 OAJ07070.1 - 1.3e-16 60.4 0.0 5.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ07070.1 - 8.8e-13 48.2 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ07070.1 - 9.5e-13 48.3 0.0 2.6e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ07070.1 - 2e-07 31.2 0.0 5.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ07070.1 - 0.00043 20.5 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 OAJ07070.1 - 0.0076 15.8 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ResB PF05140.14 OAJ07147.1 - 0.062 12.0 0.1 0.062 12.0 0.1 1.6 2 0 0 2 2 2 0 ResB-like family MSA-2c PF12238.8 OAJ07147.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Rhomboid PF01694.22 OAJ07222.1 - 4.3e-28 98.2 11.2 4.3e-28 98.2 11.2 2.1 3 0 0 3 3 3 1 Rhomboid family Intg_mem_TP0381 PF09529.10 OAJ07222.1 - 0.012 15.1 3.1 0.27 10.7 1.1 3.1 3 1 0 3 3 3 0 Integral membrane protein (intg_mem_TP0381) DUF3671 PF12420.8 OAJ07222.1 - 0.24 11.5 0.9 0.56 10.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF4006 PF13179.6 OAJ07223.1 - 1.6 8.7 3.4 1.2 9.1 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Macoilin PF09726.9 OAJ07223.1 - 8.7 4.8 5.3 11 4.4 5.3 1.1 1 0 0 1 1 1 0 Macoilin family Topoisom_bac PF01131.20 OAJ07297.1 - 2e-89 300.4 0.0 2.7e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 OAJ07297.1 - 9.6e-19 67.5 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CCHC PF00098.23 OAJ07297.1 - 1.9e-06 27.7 4.9 4.7e-06 26.4 4.9 1.7 1 0 0 1 1 1 1 Zinc knuckle TIP41 PF04176.13 OAJ07297.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 TIP41-like family zf-CCHC_3 PF13917.6 OAJ07297.1 - 0.14 12.2 1.8 0.33 10.9 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle OHCU_decarbox PF09349.10 OAJ07297.1 - 0.16 12.5 0.2 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 OHCU decarboxylase zf-CCHC_2 PF13696.6 OAJ07297.1 - 1.3 8.9 4.5 2.5 8.0 4.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.27 OAJ07300.1 - 1.9e-24 86.4 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ07300.1 - 3.6e-22 78.3 0.0 1.1e-13 51.0 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ07300.1 - 3e-17 62.8 0.0 1.9e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ07300.1 - 7.1e-16 58.1 0.1 1.4e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ07300.1 - 6.6e-11 42.4 0.0 2.1e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ07300.1 - 7.9e-05 23.2 0.0 0.00033 21.2 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ07300.1 - 0.005 17.4 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ07300.1 - 0.013 15.8 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-H2C2 PF09337.10 OAJ07300.1 - 0.02 15.1 0.0 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 H2C2 zinc finger TMEM208_SND2 PF05620.11 OAJ07384.1 - 9.3e-38 129.6 10.8 2.3e-37 128.4 10.8 1.6 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ribosomal_S28e PF01200.18 OAJ07385.1 - 2.2e-31 107.6 0.6 2.5e-31 107.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Pec_lyase_C PF00544.19 OAJ07385.1 - 0.16 11.5 0.0 0.19 11.3 0.0 1.0 1 0 0 1 1 1 0 Pectate lyase UEV PF05743.13 OAJ07386.1 - 3.9e-37 126.8 0.1 6e-37 126.2 0.1 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 OAJ07386.1 - 1e-23 83.0 0.4 2.1e-23 82.0 0.4 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 OAJ07386.1 - 0.00032 20.4 0.0 0.00083 19.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HEAT PF02985.22 OAJ07389.1 - 1.5e-05 24.8 0.7 1.2 9.6 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat Pkinase PF00069.25 OAJ07389.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 OAJ07389.1 - 0.0017 18.5 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 OAJ07389.1 - 0.0059 17.1 3.1 0.02 15.4 0.2 3.5 4 0 0 4 4 4 1 HEAT-like repeat DUF1217 PF06748.12 OAJ07389.1 - 0.099 12.7 0.1 0.23 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) TFIIF_alpha PF05793.12 OAJ07477.1 - 3.6 6.1 38.5 11 4.5 38.5 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 OAJ07477.1 - 3.9 6.8 34.5 14 5.0 34.5 1.9 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ07477.1 - 7.3 4.7 25.2 21 3.3 25.2 1.7 1 0 0 1 1 1 0 CDC45-like protein SRI PF08236.11 OAJ07482.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Nop14 PF04147.12 OAJ07482.1 - 2.5 6.2 8.6 4.2 5.5 8.6 1.4 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 OAJ07565.1 - 5.3e-09 35.9 0.0 5.3e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3762 PF12591.8 OAJ07565.1 - 0.058 13.6 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) rve PF00665.26 OAJ07566.1 - 1.7e-15 57.2 0.0 3.6e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ07566.1 - 0.0033 17.2 0.0 0.0082 15.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ07566.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase zinc binding domain Phage_integrase PF00589.22 OAJ07569.1 - 0.0056 16.5 0.2 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Phage integrase family DNA_pol3_tau_4 PF12168.8 OAJ07569.1 - 0.12 12.9 1.3 0.19 12.3 0.2 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Presenilin PF01080.17 OAJ07570.1 - 2.9 6.6 4.4 2.4 6.8 4.4 1.0 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 OAJ07570.1 - 4.1 7.7 24.8 5.5 7.3 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RVT_1 PF00078.27 OAJ07635.1 - 3.2e-21 75.9 0.0 4.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ07635.1 - 5.3e-05 23.8 0.0 0.00013 22.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ07635.1 - 0.017 15.7 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ07635.1 - 0.044 14.1 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease RHD3 PF05879.12 OAJ07639.1 - 0.0042 15.3 0.0 0.0043 15.3 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Thi4 PF01946.17 OAJ07640.1 - 5.4e-94 313.8 0.1 6.9e-94 313.5 0.1 1.1 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAJ07640.1 - 1.6e-06 27.4 2.7 0.00051 19.2 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ07640.1 - 5.3e-06 26.6 0.1 1.5e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ07640.1 - 6.6e-06 25.9 0.5 4.6e-05 23.2 0.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ07640.1 - 0.00038 19.8 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ07640.1 - 0.0014 18.6 0.0 0.0038 17.2 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAJ07640.1 - 0.002 17.3 1.7 0.041 13.0 0.3 2.6 2 1 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 OAJ07640.1 - 0.004 16.6 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ07640.1 - 0.07 11.8 0.1 0.099 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Cpn60_TCP1 PF00118.24 OAJ07719.1 - 2.3e-147 491.6 13.7 7.8e-93 311.7 4.7 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Stomoxyn PF11585.8 OAJ07719.1 - 9.3 6.4 9.1 38 4.4 0.0 4.2 4 0 0 4 4 4 0 Insect antimicrobial peptide, stomoxyn RGS PF00615.19 OAJ07720.1 - 1.1e-11 45.1 0.0 1.1e-07 32.2 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain SSP160 PF06933.11 OAJ07813.1 - 0.36 9.0 12.9 0.54 8.4 12.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.11 OAJ07813.1 - 1 9.3 9.5 1.9 8.4 9.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus LIP PF03583.14 OAJ07817.1 - 1.5e-48 165.6 0.0 2.1e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ07817.1 - 0.0015 18.1 0.5 0.019 14.4 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ07817.1 - 0.0027 17.0 0.1 0.077 12.2 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Pept_S41_N PF18294.1 OAJ07817.1 - 0.16 11.9 0.1 0.53 10.3 0.1 1.9 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain LIP PF03583.14 OAJ07818.1 - 1e-06 28.3 0.0 1.1e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ07818.1 - 0.028 13.9 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family NAD_binding_4 PF07993.12 OAJ08016.1 - 1.2e-24 86.9 0.0 2.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ08016.1 - 1.8e-15 57.0 0.0 4.3e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 OAJ08016.1 - 1.1e-09 37.4 0.0 6.5e-07 28.3 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme GDP_Man_Dehyd PF16363.5 OAJ08016.1 - 1.6e-06 27.8 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ08016.1 - 0.00022 20.4 0.0 0.00089 18.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ08016.1 - 0.0036 17.2 0.1 0.03 14.2 0.1 2.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ08016.1 - 0.0044 16.2 0.0 0.39 9.8 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 OAJ08016.1 - 0.012 15.5 0.3 0.3 11.0 0.0 3.0 1 1 1 2 2 2 0 NAD(P)H-binding AMP-binding_C PF13193.6 OAJ08016.1 - 0.054 14.5 0.2 0.28 12.2 0.1 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Kelch_4 PF13418.6 OAJ08018.1 - 1.3e-20 73.1 0.5 2e-06 27.7 0.0 7.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ08018.1 - 4.1e-12 45.8 1.8 0.0076 16.2 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 OAJ08018.1 - 6.1e-12 45.4 3.6 0.00036 20.7 0.1 5.4 5 1 1 6 6 6 2 Kelch motif Kelch_1 PF01344.25 OAJ08018.1 - 4.6e-09 35.7 0.0 0.031 13.9 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 OAJ08018.1 - 4.3e-08 33.2 15.0 0.77 10.1 0.1 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ08018.1 - 0.00045 20.1 0.0 7 6.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Cupin_8 PF13621.6 OAJ08023.1 - 1.3e-41 143.0 3.1 1.6e-22 80.5 0.0 5.0 4 1 0 4 4 4 2 Cupin-like domain ANAPC15 PF15243.6 OAJ08023.1 - 0.0038 17.6 5.7 0.0038 17.6 5.7 9.6 7 2 3 10 10 10 1 Anaphase-promoting complex subunit 15 Clathrin_H_link PF13838.6 OAJ08024.1 - 4.6e-28 96.9 0.1 8.4e-28 96.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin-H-link Luciferase_N PF05295.11 OAJ08024.1 - 0.66 10.0 2.7 4.7 7.3 0.2 2.8 3 0 0 3 3 3 0 Luciferase/LBP N-terminal domain DUF1542 PF07564.11 OAJ08027.1 - 0.043 13.9 0.3 0.078 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) CbiC PF02570.15 OAJ08027.1 - 0.14 11.8 0.3 0.29 10.7 0.2 1.5 1 1 1 2 2 2 0 Precorrin-8X methylmutase SSP160 PF06933.11 OAJ08031.1 - 0.025 12.8 9.3 0.033 12.4 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aldo_ket_red PF00248.21 OAJ08032.1 - 8.9e-43 146.6 0.0 1e-41 143.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ish1 PF10281.9 OAJ08032.1 - 0.036 14.4 0.0 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 OAJ08032.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Slx4 endonuclease RVT_1 PF00078.27 OAJ08037.1 - 1.7e-23 83.3 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08037.1 - 6.2e-23 80.7 0.0 8.5e-15 54.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08037.1 - 1.5e-16 60.5 0.0 1.3e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08037.1 - 5.2e-13 48.9 0.0 9.7e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08037.1 - 1e-10 41.9 0.0 4.1e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08037.1 - 0.00016 22.3 0.0 0.00075 20.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease dUTPase PF00692.19 OAJ08037.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 dUTPase DUF3486 PF11985.8 OAJ08037.1 - 0.067 13.6 0.2 12 6.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) gag-asp_proteas PF13975.6 OAJ08037.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 OAJ08041.1 - 2.4e-22 79.5 0.0 4.1e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08041.1 - 1.1e-15 57.4 0.0 2.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08041.1 - 5.5e-12 45.9 0.0 1.1e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08041.1 - 0.00042 20.9 0.2 0.0016 19.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ08041.1 - 0.089 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger MULE PF10551.9 OAJ08046.1 - 8e-11 42.2 0.0 2.4e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ08046.1 - 1.1e-07 31.4 0.2 2.1e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger PRK PF00485.18 OAJ08051.1 - 3.9e-07 30.0 0.0 6.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 OAJ08051.1 - 3.3e-05 24.4 0.0 0.00024 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 OAJ08051.1 - 0.031 14.2 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 OAJ08051.1 - 0.054 13.7 0.2 0.16 12.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ08051.1 - 0.1 13.0 0.9 0.57 10.5 0.4 2.5 2 1 0 2 2 2 0 AAA ATPase domain GMC_oxred_N PF00732.19 OAJ08053.1 - 5.1e-48 164.0 0.2 1.2e-24 87.3 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ08053.1 - 9.2e-07 29.5 0.0 2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ08053.1 - 6.8e-06 26.2 0.2 2.3e-05 24.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ08053.1 - 1.2e-05 24.6 0.3 0.00061 19.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ08053.1 - 3.4e-05 23.1 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAJ08053.1 - 0.00067 19.0 0.1 0.0019 17.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ08053.1 - 0.0034 17.0 1.5 0.0078 15.8 0.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ08053.1 - 0.0097 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 OAJ08053.1 - 0.019 13.7 0.1 0.068 11.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 OAJ08053.1 - 0.029 14.6 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.19 OAJ08053.1 - 0.04 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 OAJ08053.1 - 0.067 12.4 0.1 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ08053.1 - 0.073 13.1 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF4731 PF15875.5 OAJ08053.1 - 0.12 12.6 0.2 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4731) Aldo_ket_red PF00248.21 OAJ08054.1 - 4.6e-48 163.9 0.0 5.3e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.23 OAJ08056.1 - 7.4e-26 90.5 4.1 1.5e-25 89.5 2.7 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ08056.1 - 2.6e-06 27.4 0.2 4.6e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like SprB PF13573.6 OAJ08056.1 - 0.09 12.6 1.5 0.81 9.5 0.1 3.2 3 0 0 3 3 3 0 SprB repeat DUF1829 PF08862.10 OAJ08056.1 - 0.16 12.5 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF1829 LIP PF03583.14 OAJ08062.1 - 1.6e-20 73.6 0.0 1.8e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Secretory lipase SelP_N PF04592.14 OAJ08063.1 - 1.1 8.6 6.8 1.5 8.2 6.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MULE PF10551.9 OAJ08067.1 - 3e-06 27.5 0.2 0.0024 18.3 0.1 2.8 2 1 1 3 3 3 2 MULE transposase domain DDE_Tnp_4 PF13359.6 OAJ08080.1 - 1.7e-31 109.0 0.0 2e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ08080.1 - 5.9e-09 35.9 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ08080.1 - 8.7e-08 32.0 0.0 1.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Plant transposon protein Pmp3 PF01679.17 OAJ08086.1 - 2.8e-12 46.6 3.6 5e-12 45.8 3.6 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator GST_C_2 PF13410.6 OAJ08087.1 - 2.5e-16 59.5 0.0 4.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ08087.1 - 6e-15 55.3 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ08087.1 - 3.9e-07 30.2 0.0 7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ08087.1 - 9.7e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ08087.1 - 0.0066 16.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Mto2_bdg PF12808.7 OAJ08092.1 - 0.0045 17.3 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region BBP1_C PF15272.6 OAJ08092.1 - 0.0047 16.8 0.1 0.0056 16.5 0.1 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BRE1 PF08647.11 OAJ08092.1 - 0.035 14.2 0.3 0.04 14.0 0.3 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Sec2p PF06428.11 OAJ08092.1 - 0.048 13.6 0.3 0.058 13.4 0.3 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p RVT_1 PF00078.27 OAJ08094.1 - 1.9e-24 86.4 0.0 3.5e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08094.1 - 2e-22 79.1 0.0 2.6e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08094.1 - 4e-15 56.0 0.0 6.6e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08094.1 - 3e-14 52.9 0.0 5.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08094.1 - 5.1e-09 36.3 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08094.1 - 0.00011 22.7 0.0 0.0004 21.0 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08094.1 - 0.016 15.8 0.0 0.052 14.1 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ08094.1 - 0.054 13.7 0.4 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 H2C2 zinc finger TPR_12 PF13424.6 OAJ08099.1 - 1.9e-29 101.7 57.8 0.00046 20.4 4.8 14.1 7 5 6 13 13 13 9 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ08099.1 - 6.7e-29 98.9 50.6 0.0095 15.8 0.0 15.7 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08099.1 - 3.4e-11 42.4 27.3 2.5 8.4 0.2 13.1 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08099.1 - 1e-05 25.1 9.6 12 5.9 0.0 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat Phage_tail_U PF06141.11 OAJ08099.1 - 0.007 16.7 0.7 0.6 10.5 0.0 4.2 5 1 1 6 6 6 1 Phage minor tail protein U DUF4754 PF15946.5 OAJ08099.1 - 0.018 15.3 16.7 0.42 10.9 0.5 5.2 3 1 1 5 5 5 0 Domain of unknown function (DUF4754) SPG48 PF14764.6 OAJ08099.1 - 0.025 15.0 0.1 9.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF3856 PF12968.7 OAJ08099.1 - 0.035 14.2 21.0 0.24 11.4 1.2 6.6 3 3 6 9 9 9 0 Domain of Unknown Function (DUF3856) Phage_term_smal PF05944.12 OAJ08099.1 - 0.045 13.7 0.4 16 5.5 0.0 3.5 3 1 1 4 4 4 0 Phage small terminase subunit M PF02370.16 OAJ08099.1 - 0.054 14.0 0.8 1 10.1 1.3 3.1 2 0 0 2 2 1 0 M protein repeat Zwint PF15556.6 OAJ08099.1 - 0.064 12.7 2.4 0.5 9.8 0.4 2.5 2 0 0 2 2 2 0 ZW10 interactor Prefoldin_2 PF01920.20 OAJ08099.1 - 0.29 11.1 7.2 25 4.9 0.2 5.5 6 0 0 6 6 5 0 Prefoldin subunit TPR_8 PF13181.6 OAJ08099.1 - 0.42 11.0 22.4 64 4.1 0.0 9.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ08099.1 - 0.74 10.8 45.1 4.7 8.3 1.6 12.9 13 2 2 15 15 14 0 Tetratricopeptide repeat RVT_3 PF13456.6 OAJ08102.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ08102.1 - 0.0061 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RT_RNaseH_2 PF17919.1 OAJ08102.1 - 0.039 14.0 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Phage_integrase PF00589.22 OAJ08103.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family DOT1 PF08123.13 OAJ08104.1 - 6.2e-65 218.6 0.0 8.3e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Romo1 PF10247.9 OAJ08105.1 - 3.9e-11 43.1 2.4 4.7e-11 42.9 2.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Acetyltransf_1 PF00583.25 OAJ08107.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ08107.1 - 0.011 16.1 0.1 0.039 14.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 OAJ08110.1 - 3.1e-48 163.9 0.0 6.3e-48 162.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ08110.1 - 8.6e-27 93.7 0.1 3.9e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ08110.1 - 4.3e-18 65.3 0.0 1.4e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ08110.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ08110.1 - 0.00027 20.2 0.4 0.00054 19.3 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_60s PF00428.19 OAJ08110.1 - 2.7 8.6 10.5 6.4 7.4 0.1 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3391 PF11871.8 OAJ08110.1 - 5.7 7.5 8.5 0.32 11.5 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DDE_3 PF13358.6 OAJ08118.1 - 1.3e-17 64.0 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 OAJ08118.1 - 0.0058 15.7 0.0 0.0058 15.7 0.0 1.1 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain rve PF00665.26 OAJ08118.1 - 0.027 14.7 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Pkinase_C PF00433.24 OAJ08124.1 - 0.28 11.9 3.9 4.8 8.0 0.4 3.9 3 0 0 3 3 3 0 Protein kinase C terminal domain GMC_oxred_N PF00732.19 OAJ08126.1 - 1.3e-49 169.2 0.0 1.7e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ08126.1 - 7.5e-35 120.6 0.1 1.3e-34 119.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAJ08126.1 - 0.00017 21.0 0.3 0.12 11.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ08126.1 - 0.00017 20.8 0.7 0.0082 15.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ08126.1 - 0.0002 21.5 0.7 0.00051 20.2 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 OAJ08126.1 - 0.00046 19.4 0.2 0.00069 18.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 OAJ08126.1 - 0.0038 16.5 0.1 0.01 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ08126.1 - 0.0049 16.5 0.5 0.012 15.2 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase COR PF16095.5 OAJ08126.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain FAD_binding_3 PF01494.19 OAJ08126.1 - 0.072 12.3 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAJ08126.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF3336 PF11815.8 OAJ08132.1 - 1.2e-46 157.8 1.1 2.1e-46 157.0 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 OAJ08132.1 - 9e-19 68.5 3.0 6.2e-18 65.7 0.2 3.4 3 1 0 3 3 3 1 Patatin-like phospholipase TadE PF07811.12 OAJ08132.1 - 2.9 8.3 9.0 0.27 11.5 3.9 2.0 2 0 0 2 2 2 0 TadE-like protein AAA_lid_7 PF17867.1 OAJ08136.1 - 0.084 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain RGS PF00615.19 OAJ08137.1 - 6.7e-06 26.4 0.1 3.2e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain MutS_V PF00488.21 OAJ08142.1 - 8.2e-38 130.3 0.0 2.2e-37 128.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ08142.1 - 9.3e-23 81.4 1.4 1e-22 81.3 0.2 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 OAJ08142.1 - 4.9e-06 26.9 1.7 0.066 13.5 1.2 3.5 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 OAJ08142.1 - 1.1e-05 25.7 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV SMC_N PF02463.19 OAJ08142.1 - 0.0076 15.7 0.1 1.5 8.2 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ08142.1 - 0.089 13.1 0.1 0.33 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain Orthopox_F6 PF06601.12 OAJ08142.1 - 0.11 12.6 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Orthopoxvirus F6 protein PRCH PF03967.13 OAJ08145.1 - 0.074 13.3 0.2 0.14 12.4 0.2 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region tRNA-synt_1b PF00579.25 OAJ08146.1 - 4.4e-19 68.9 0.0 2.2e-18 66.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NgoMIV_restric PF09015.10 OAJ08149.1 - 0.048 12.8 0.0 0.053 12.6 0.0 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme Peptidase_S55 PF05580.12 OAJ08149.1 - 0.16 11.9 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 SpoIVB peptidase S55 Abhydrolase_3 PF07859.13 OAJ08152.1 - 1.4e-19 70.8 0.0 2.8e-19 69.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ08152.1 - 1.4e-07 30.7 0.0 0.0045 15.9 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase NDC10_II PF16787.5 OAJ08157.1 - 1.1e-41 143.0 0.0 1.5e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 RVT_2 PF07727.14 OAJ08166.1 - 2e-60 204.5 0.0 2.8e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08166.1 - 4e-12 46.4 0.2 1.9e-11 44.2 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08166.1 - 0.00048 19.9 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_3 PF13456.6 OAJ08166.1 - 0.045 13.6 0.6 0.68 9.7 0.2 2.7 2 0 0 2 2 2 0 Reverse transcriptase-like rve_3 PF13683.6 OAJ08166.1 - 0.52 10.1 2.1 0.76 9.6 0.0 2.3 3 0 0 3 3 3 0 Integrase core domain NDC10_II PF16787.5 OAJ08178.1 - 1.1e-63 215.2 0.0 1.6e-63 214.7 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ08178.1 - 1.4e-17 63.8 0.1 3.5e-17 62.5 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3090 PF11290.8 OAJ08185.1 - 0.24 11.2 1.7 2.2 8.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3090) Sec7 PF01369.20 OAJ08186.1 - 3.9e-29 101.6 0.2 6.5e-29 100.9 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ08186.1 - 3e-08 34.1 0.1 3.2e-07 30.8 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 OAJ08186.1 - 0.0014 19.0 0.5 0.0065 16.8 0.3 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain CAP PF00188.26 OAJ08193.1 - 5.3e-21 75.8 3.8 7.1e-21 75.4 2.2 1.9 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Na_Ca_ex PF01699.24 OAJ08197.1 - 1e-32 113.2 26.7 1.5e-17 63.9 9.9 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CENP-B_dimeris PF09026.10 OAJ08197.1 - 1.4 9.3 9.8 8.4 6.9 1.8 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain DDE_1 PF03184.19 OAJ08205.1 - 1.2e-16 60.9 0.0 5.1e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAJ08205.1 - 0.0061 16.3 0.0 1 9.1 0.0 2.6 2 1 1 3 3 3 3 DDE superfamily endonuclease Nop53 PF07767.11 OAJ08206.1 - 1.8 7.9 28.9 2.1 7.7 28.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 OAJ08206.1 - 4.5 5.4 19.1 5.1 5.3 19.1 1.0 1 0 0 1 1 1 0 CDC45-like protein CCDC71L PF15374.6 OAJ08206.1 - 4.8 6.3 14.1 5.5 6.1 14.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Presenilin PF01080.17 OAJ08206.1 - 6.3 5.4 12.8 7.7 5.2 12.8 1.0 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 OAJ08206.1 - 9 6.5 11.4 10 6.3 11.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 OAJ08206.1 - 9.7 5.9 16.7 12 5.7 16.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Frataxin_Cyay PF01491.16 OAJ08219.1 - 5.7e-31 106.8 0.0 8.5e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain TPPII_N PF12583.8 OAJ08219.1 - 0.0079 16.8 0.9 0.012 16.2 0.9 1.2 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal GEMIN8 PF15348.6 OAJ08219.1 - 0.014 15.7 0.9 0.019 15.3 0.9 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CAP_N PF01213.19 OAJ08219.1 - 0.23 10.9 2.3 0.31 10.5 2.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4551 PF15087.6 OAJ08219.1 - 0.96 8.2 3.8 1.2 7.9 3.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.19 OAJ08219.1 - 1.2 8.9 6.6 1.5 8.6 6.6 1.1 1 0 0 1 1 1 0 SPX domain Ric8 PF10165.9 OAJ08220.1 - 1.8e-73 248.2 4.1 3.3e-43 148.4 0.0 2.3 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn U1snRNP70_N PF12220.8 OAJ08220.1 - 0.58 10.8 4.1 1.2 9.8 2.6 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RVT_2 PF07727.14 OAJ08224.1 - 3.7e-45 154.5 0.0 4.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 OAJ08225.1 - 0.0076 16.1 0.1 0.018 14.9 0.0 1.6 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 OAJ08225.1 - 0.029 14.1 0.9 0.077 12.7 0.9 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 OAJ08225.1 - 0.035 14.2 2.3 0.035 14.2 2.3 1.9 2 0 0 2 2 2 0 Zinc knuckle RVP PF00077.20 OAJ08225.1 - 0.076 13.3 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Retrotran_gag_2 PF14223.6 OAJ08226.1 - 2.1e-05 24.2 0.0 2.2e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MULE PF10551.9 OAJ08229.1 - 7.1e-24 84.1 0.6 1.8e-23 82.8 0.2 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ08229.1 - 0.00038 19.4 0.0 0.0064 15.4 0.0 2.1 2 0 0 2 2 2 1 Transposase, Mutator family DUF3047 PF11249.8 OAJ08229.1 - 0.045 13.2 0.2 0.29 10.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3047) Glyco_hydro_cc PF11790.8 OAJ08230.1 - 5.1e-46 157.2 3.4 5.8e-46 157.0 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core CDC45 PF02724.14 OAJ08237.1 - 7.1e-203 675.4 0.0 2e-202 674.0 0.0 1.6 1 1 0 1 1 1 1 CDC45-like protein Cas_Csy4 PF09618.10 OAJ08237.1 - 0.06 13.5 0.1 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) DUF4604 PF15377.6 OAJ08237.1 - 1.2 9.5 33.8 1 9.7 24.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Apt1 PF10351.9 OAJ08237.1 - 1.6 7.5 7.1 3.3 6.5 7.1 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 OAJ08237.1 - 1.7 7.9 42.1 3.3 7.0 35.1 2.1 2 0 0 2 2 2 0 BUD22 RVT_1 PF00078.27 OAJ08243.1 - 3.1e-24 85.7 0.0 4.8e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ08243.1 - 4.2e-13 49.2 0.1 1e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ08243.1 - 7.6e-09 35.9 0.3 3.8e-08 33.6 0.1 2.4 2 1 0 2 2 2 1 RNase H Exo_endo_phos PF03372.23 OAJ08243.1 - 4.6e-05 23.0 0.7 0.00048 19.7 0.7 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC_export PF16962.5 OAJ08243.1 - 0.26 9.7 0.0 0.39 9.1 0.0 1.1 1 0 0 1 1 1 0 Putative ABC exporter Fez1 PF06818.15 OAJ08246.1 - 0.32 11.4 9.0 0.46 10.9 8.5 1.4 1 1 0 1 1 1 0 Fez1 DivIVA PF05103.13 OAJ08246.1 - 0.47 10.5 8.4 0.83 9.7 8.4 1.3 1 0 0 1 1 1 0 DivIVA protein Seryl_tRNA_N PF02403.22 OAJ08246.1 - 0.96 9.7 12.4 3.5 7.9 11.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 OAJ08246.1 - 1.1 9.1 11.9 0.75 9.6 2.5 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 OAJ08246.1 - 1.4 8.2 11.9 2.9 7.1 11.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 OAJ08246.1 - 1.8 8.6 10.2 5.3 7.1 10.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5320 PF17253.2 OAJ08246.1 - 2.5 9.2 5.3 15 6.7 0.5 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Phage_GP20 PF06810.11 OAJ08246.1 - 2.8 7.7 12.7 5.6 6.8 5.7 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4140 PF13600.6 OAJ08246.1 - 4.2 7.9 11.6 6.2 7.3 1.9 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.12 OAJ08246.1 - 4.4 7.4 17.2 0.15 12.1 4.6 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Retrotrans_gag PF03732.17 OAJ08250.1 - 0.97 9.8 3.7 0.61 10.4 0.4 2.0 2 0 0 2 2 2 0 Retrotransposon gag protein GRP PF07172.11 OAJ08250.1 - 1.6 9.4 29.2 2.8 8.7 29.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family THOC7 PF05615.13 OAJ08255.1 - 3.1e-17 63.1 4.3 3.1e-17 63.1 4.3 2.5 1 1 1 2 2 2 1 Tho complex subunit 7 IFT20 PF14931.6 OAJ08255.1 - 0.018 15.2 4.4 0.034 14.3 0.4 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Phlebovirus_NSM PF07246.11 OAJ08255.1 - 0.038 13.4 1.7 0.041 13.3 0.3 1.7 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Occludin_ELL PF07303.13 OAJ08255.1 - 0.1 13.3 1.1 0.28 11.9 1.1 1.8 1 0 0 1 1 1 0 Occludin homology domain APG6_N PF17675.1 OAJ08255.1 - 3 8.4 15.3 7.9 7.0 6.0 2.6 1 1 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 OAJ08255.1 - 4.7 7.3 12.4 6.8 6.8 4.2 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FliJ PF02050.16 OAJ08255.1 - 6 7.1 15.2 1.9 8.7 2.5 2.7 3 0 0 3 3 3 0 Flagellar FliJ protein DUF2968 PF11180.8 OAJ08255.1 - 8.7 5.9 18.4 1.1 8.9 11.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) NDC10_II PF16787.5 OAJ08264.1 - 6.8e-62 209.3 0.0 1.3e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ08264.1 - 5.1e-21 74.8 0.9 1.1e-20 73.8 0.9 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Steroid_dh PF02544.16 OAJ08270.1 - 1.7e-32 112.5 0.5 2.8e-32 111.8 0.5 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAJ08270.1 - 2.1e-07 30.7 0.1 3.5e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 OAJ08270.1 - 2.5e-06 27.2 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ICMT PF04140.14 OAJ08270.1 - 0.0013 19.2 0.2 0.0029 18.0 0.2 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ08270.1 - 0.0031 17.9 0.9 0.012 16.0 0.4 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase MFAP1 PF06991.11 OAJ08271.1 - 0.0039 17.1 2.8 0.0072 16.2 2.8 1.4 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DUF2986 PF11661.8 OAJ08271.1 - 0.012 16.1 0.4 0.012 16.1 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2986) TerB_C PF15615.6 OAJ08271.1 - 5 7.4 7.8 1.5 9.1 2.8 2.1 2 0 0 2 2 2 0 TerB-C domain Retrotran_gag_2 PF14223.6 OAJ08272.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type AAA PF00004.29 OAJ08276.1 - 5.8e-44 149.7 0.0 1e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ08276.1 - 3.7e-10 39.4 0.1 8e-10 38.4 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ08276.1 - 2.7e-08 34.1 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 OAJ08276.1 - 1.3e-07 31.4 0.5 2.9e-07 30.3 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ08276.1 - 2.3e-06 27.6 0.0 8.5e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ08276.1 - 6.6e-06 26.6 0.0 8.1e-05 23.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ08276.1 - 6.7e-06 26.4 0.4 0.0055 17.0 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ08276.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ08276.1 - 0.0011 19.5 0.3 0.018 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 OAJ08276.1 - 0.0011 18.2 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 OAJ08276.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAJ08276.1 - 0.0026 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 OAJ08276.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAJ08276.1 - 0.0056 16.2 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 OAJ08276.1 - 0.0079 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAJ08276.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ08276.1 - 0.013 15.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 OAJ08276.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 OAJ08276.1 - 0.018 14.4 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 OAJ08276.1 - 0.022 14.4 0.0 0.11 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 OAJ08276.1 - 0.031 13.5 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 OAJ08276.1 - 0.032 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ08276.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ08276.1 - 0.044 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 OAJ08276.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_25 PF13481.6 OAJ08276.1 - 0.066 12.8 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 OAJ08276.1 - 0.068 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APG6_N PF17675.1 OAJ08276.1 - 0.078 13.5 0.8 0.16 12.5 0.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region RILP PF11461.8 OAJ08276.1 - 0.095 12.9 1.2 0.2 11.9 1.2 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein Zeta_toxin PF06414.12 OAJ08276.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 OAJ08276.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAJ08276.1 - 0.14 12.5 0.1 0.49 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Amidase PF01425.21 OAJ08277.1 - 2.9e-79 267.1 0.0 1.2e-64 219.0 0.1 2.1 2 0 0 2 2 2 2 Amidase Minor_tail_Z PF06763.11 OAJ08277.1 - 0.096 12.5 0.0 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) ANAPC3 PF12895.7 OAJ08285.1 - 1.1e-06 28.8 7.7 2.2 8.5 0.3 6.3 5 2 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAJ08285.1 - 2.6e-06 27.6 35.2 0.037 14.3 3.2 7.7 6 4 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ08285.1 - 2.9e-05 23.9 28.0 1.4 9.2 0.5 9.2 11 0 0 11 11 11 2 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ08285.1 - 0.0024 17.9 9.8 2 8.6 0.4 5.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 OAJ08285.1 - 0.0026 18.4 32.6 1.1 10.2 0.3 8.5 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ08285.1 - 0.012 15.7 12.5 20 5.7 0.1 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ08285.1 - 0.52 11.0 24.6 5.1 7.8 5.8 6.6 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ08285.1 - 0.56 10.1 17.3 1.1 9.2 0.1 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ08285.1 - 0.67 10.5 30.1 3.3 8.3 0.4 6.4 4 4 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ08285.1 - 0.69 9.9 32.2 1.8 8.6 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ08285.1 - 5.6 6.7 9.0 78 3.1 0.0 4.9 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 OAJ08285.1 - 7.6 7.5 34.7 0.44 11.3 1.0 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat PBP1_TM PF14812.6 OAJ08286.1 - 2.3 8.7 11.8 0.79 10.1 7.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 OAJ08286.1 - 6.1 7.1 13.5 0.1 12.9 4.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Polysacc_deac_1 PF01522.21 OAJ08288.1 - 6.7e-05 22.8 0.0 9.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase MULE PF10551.9 OAJ08297.1 - 6.3e-22 77.8 0.0 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ08297.1 - 0.00032 21.3 0.7 0.00075 20.2 0.7 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain RVT_1 PF00078.27 OAJ08300.1 - 1.2e-24 87.1 0.0 2e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08300.1 - 6.5e-21 74.3 0.0 1.6e-13 50.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08300.1 - 1e-15 57.9 0.0 7.1e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08300.1 - 3.5e-15 55.9 0.5 6.2e-15 55.0 0.5 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08300.1 - 4.1e-11 43.1 0.0 9.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08300.1 - 0.00021 21.9 0.0 0.00062 20.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08300.1 - 0.013 16.0 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Flavokinase PF01687.17 OAJ08303.1 - 1.1e-30 106.2 0.0 1.3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Metallophos PF00149.28 OAJ08304.1 - 6.3e-06 26.8 1.7 8.2e-05 23.2 0.4 2.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Dishevelled PF02377.15 OAJ08304.1 - 0.57 10.6 8.1 0.077 13.4 3.3 2.0 2 0 0 2 2 2 0 Dishevelled specific domain MCM PF00493.23 OAJ08307.1 - 4e-17 62.1 0.0 5.9e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ08307.1 - 0.00083 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain Ribosomal_L3 PF00297.22 OAJ08308.1 - 1e-182 607.2 7.1 1.1e-182 607.0 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3619 PF12279.8 OAJ08311.1 - 0.02 15.2 0.3 0.023 15.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Dicty_REP PF05086.12 OAJ08311.1 - 0.46 8.4 1.6 0.47 8.4 1.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SPATA24 PF15175.6 OAJ08312.1 - 0.056 13.3 3.5 0.15 12.0 0.5 2.0 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 rve PF00665.26 OAJ08317.1 - 4.8e-15 55.8 0.1 1e-14 54.7 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08317.1 - 0.0032 17.2 0.0 0.0098 15.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain CIAPIN1 PF05093.13 OAJ08318.1 - 3.8e-32 110.8 1.9 8.9e-32 109.6 1.9 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 OAJ08318.1 - 4.7e-08 33.3 0.0 7.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus HsbA PF12296.8 OAJ08324.1 - 1.1e-16 61.4 14.9 1.1e-16 61.4 14.9 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A RVT_N PF13655.6 OAJ08324.1 - 0.07 13.4 1.5 5.8 7.2 1.5 2.3 1 1 0 1 1 1 0 N-terminal domain of reverse transcriptase Glyco_trans_2_3 PF13632.6 OAJ08334.1 - 3.4e-20 72.8 4.2 3.4e-20 72.8 4.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 OAJ08334.1 - 1.5e-18 67.5 0.0 2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ08334.1 - 1.1e-09 38.0 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ08334.1 - 2.6e-07 30.6 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ribosomal_L29e PF01779.17 OAJ08335.1 - 6.6e-09 35.9 1.0 1.1e-08 35.2 1.0 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family RT_RNaseH_2 PF17919.1 OAJ08338.1 - 9.3e-22 77.0 0.1 2.4e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08338.1 - 5.4e-20 71.9 0.0 9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08338.1 - 6.8e-11 42.4 0.0 2e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ08338.1 - 1.6e-09 38.0 0.0 0.00031 21.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase An_peroxidase PF03098.15 OAJ08343.1 - 8.7e-40 136.8 0.1 1.2e-11 44.0 0.0 4.0 2 1 2 4 4 4 4 Animal haem peroxidase EMC3_TMCO1 PF01956.16 OAJ08344.1 - 3.4e-57 192.9 0.7 4.2e-57 192.6 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Cwf_Cwc_15 PF04889.12 OAJ08345.1 - 2.4e-74 250.2 20.9 3.3e-74 249.7 20.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ08345.1 - 0.76 7.9 37.3 0.98 7.6 37.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ08345.1 - 3.9 6.7 29.5 5.5 6.2 29.5 1.3 1 0 0 1 1 1 0 BUD22 Histone_H2A_C PF16211.5 OAJ08350.1 - 2.3e-18 65.6 0.8 4.8e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ08350.1 - 5.1e-13 49.5 0.0 6.9e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SPRY PF00622.28 OAJ08354.1 - 4.1e-21 75.3 0.2 7.6e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 SPRY domain NDC10_II PF16787.5 OAJ08366.1 - 1.2e-10 41.0 0.2 2.1e-10 40.2 0.2 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ08366.1 - 4.3e-10 39.8 0.3 4.3e-10 39.8 0.3 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Mak16 PF04874.14 OAJ08368.1 - 0.08 13.5 2.3 0.16 12.6 2.3 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region NOA36 PF06524.12 OAJ08368.1 - 5.7 6.2 6.9 12 5.1 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ08368.1 - 7.6 4.5 11.2 12 3.9 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi RAI16-like PF10257.9 OAJ08371.1 - 6.2e-53 179.9 0.0 1.8e-52 178.4 0.0 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein PGA2 PF07543.12 OAJ08371.1 - 0.45 10.5 5.3 2.8 7.9 0.4 2.7 2 0 0 2 2 2 0 Protein trafficking PGA2 Hydant_A_N PF05378.13 OAJ08376.1 - 2.2e-19 69.9 0.0 2.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region Glyco_tran_28_C PF04101.16 OAJ08377.1 - 3.3e-22 79.3 0.0 5.2e-22 78.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Mo25 PF08569.11 OAJ08378.1 - 1.1e-128 429.2 0.0 2.3e-128 428.2 0.0 1.5 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.6 OAJ08378.1 - 0.039 14.3 0.0 0.68 10.4 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats Sporozoite_P67 PF05642.11 OAJ08378.1 - 3.1 5.8 18.3 5 5.1 18.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NDUF_B8 PF05821.11 OAJ08382.1 - 0.079 12.8 0.2 0.11 12.3 0.2 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Amidohydro_2 PF04909.14 OAJ08383.1 - 4.9e-05 23.3 0.1 0.00016 21.5 0.0 1.7 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.20 OAJ08383.1 - 9.2e-05 21.9 0.1 0.0004 19.8 0.1 1.9 1 1 0 1 1 1 1 Amidohydrolase family TPR_MLP1_2 PF07926.12 OAJ08386.1 - 0.0002 21.4 39.7 0.014 15.5 6.7 3.0 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein HALZ PF02183.18 OAJ08386.1 - 0.0012 19.0 0.4 0.0012 19.0 0.4 4.7 3 2 1 4 4 4 1 Homeobox associated leucine zipper Erythro-docking PF09277.11 OAJ08386.1 - 0.041 13.8 0.5 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking CENP-F_leu_zip PF10473.9 OAJ08386.1 - 0.093 12.8 30.5 1.1 9.3 9.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CcdB PF01845.17 OAJ08386.1 - 0.099 12.9 1.0 0.96 9.7 0.0 2.6 2 1 2 4 4 4 0 CcdB protein FUSC PF04632.12 OAJ08386.1 - 0.18 10.3 15.0 0.22 10.0 15.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ApoO PF09769.9 OAJ08386.1 - 0.18 11.7 5.3 0.17 11.8 0.9 2.4 1 1 1 2 2 2 0 Apolipoprotein O FAM184 PF15665.5 OAJ08386.1 - 0.31 10.8 27.4 0.28 10.9 26.4 1.4 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B DUF812 PF05667.11 OAJ08386.1 - 0.45 9.3 21.1 0.55 9.0 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DASH_Dam1 PF08653.10 OAJ08386.1 - 0.56 10.1 4.7 1.9 8.3 0.1 3.4 2 1 2 4 4 4 0 DASH complex subunit Dam1 Peptidase_S49 PF01343.18 OAJ08386.1 - 1.2 9.1 6.1 1.6 8.7 4.4 1.8 1 1 1 2 2 2 0 Peptidase family S49 COG5 PF10392.9 OAJ08386.1 - 1.3 9.2 12.1 0.21 11.7 6.5 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Spc7 PF08317.11 OAJ08386.1 - 1.4 7.7 32.0 0.056 12.3 23.8 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1690 PF07956.11 OAJ08386.1 - 1.4 9.3 28.9 0.096 13.1 14.8 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Mt_ATP-synt_B PF05405.14 OAJ08386.1 - 1.4 8.5 22.3 0.043 13.4 9.6 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4407 PF14362.6 OAJ08386.1 - 1.6 8.0 22.4 3.5 6.9 22.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATPase PF06745.13 OAJ08386.1 - 2 7.7 7.0 0.25 10.6 2.0 1.8 1 1 0 2 2 2 0 KaiC YabA PF06156.13 OAJ08386.1 - 2.1 9.0 20.1 4.8 7.9 5.5 2.7 1 1 2 3 3 3 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 OAJ08386.1 - 2.5 7.6 14.7 3.7 7.0 14.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4472 PF14739.6 OAJ08386.1 - 3.1 8.6 26.8 4.9 7.9 13.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) PIN_8 PF18476.1 OAJ08386.1 - 6.7 6.5 13.1 5.5 6.8 11.8 1.4 1 1 0 1 1 1 0 PIN like domain Jnk-SapK_ap_N PF09744.9 OAJ08386.1 - 7.4 6.8 35.5 0.64 10.2 12.3 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 KIP1 PF07765.12 OAJ08386.1 - 9.8 6.4 10.5 1.8 8.7 3.2 2.5 2 1 0 2 2 2 0 KIP1-like protein ZapB PF06005.12 OAJ08386.1 - 10 6.7 38.6 8.7 6.9 13.6 3.9 1 1 2 3 3 3 0 Cell division protein ZapB Ank_2 PF12796.7 OAJ08387.1 - 1.2e-15 57.8 0.7 2.8e-06 27.8 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ08387.1 - 5.8e-13 49.1 4.2 4.9e-05 23.8 0.7 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ08387.1 - 4.7e-10 39.5 1.2 0.00018 21.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ08387.1 - 5.7e-10 38.6 1.9 0.0074 16.7 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 OAJ08387.1 - 7.5e-10 38.8 12.6 1.7e-05 25.1 1.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat TERB2 PF15101.6 OAJ08387.1 - 0.13 12.3 5.8 0.3 11.1 5.8 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2368 PF10166.9 OAJ08387.1 - 0.7 9.5 7.3 2.4 7.8 5.2 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) RSF PF14876.6 OAJ08387.1 - 0.9 8.4 5.0 1.4 7.8 5.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Spt20 PF12090.8 OAJ08387.1 - 1.6 8.2 20.9 0.31 10.6 17.0 1.7 2 0 0 2 2 2 0 Spt20 family DUF702 PF05142.12 OAJ08387.1 - 1.7 9.1 7.3 16 5.9 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) TFIIA PF03153.13 OAJ08387.1 - 1.9 8.4 28.4 0.43 10.5 17.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 OAJ08387.1 - 1.9 8.8 7.0 0.22 11.9 1.9 1.9 2 0 0 2 2 2 0 Enhancer of polycomb-like Roughex PF06020.11 OAJ08387.1 - 2.5 7.1 7.2 5.1 6.1 7.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein ribosomal_L24 PF17136.4 OAJ08389.1 - 0.023 15.1 0.1 0.11 12.9 0.0 2.2 2 1 0 2 2 2 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 Porin_3 PF01459.22 OAJ08390.1 - 6.5e-61 206.2 0.2 7.7e-61 205.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF2911 PF11138.8 OAJ08390.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Esterase PF00756.20 OAJ08400.1 - 0.0004 20.1 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Asp2 PF16929.5 OAJ08400.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter YchF-GTPase_C PF06071.13 OAJ08402.1 - 2.6e-34 117.3 0.1 9.5e-34 115.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 OAJ08402.1 - 7.7e-17 61.4 0.0 1.6e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ08402.1 - 7.9e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Zip PF02535.22 OAJ08403.1 - 1.4e-59 202.0 8.5 1.6e-59 201.8 8.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cwf_Cwc_15 PF04889.12 OAJ08410.1 - 0.0066 16.2 28.7 0.044 13.5 11.4 2.1 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ08410.1 - 0.013 15.7 2.5 0.013 15.7 2.5 2.6 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 OMP_b-brl PF13505.6 OAJ08410.1 - 0.04 14.0 0.8 0.04 14.0 0.8 1.6 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain PPP4R2 PF09184.11 OAJ08410.1 - 0.2 11.2 16.6 0.92 9.0 6.2 2.1 2 0 0 2 2 2 0 PPP4R2 CENP-B_dimeris PF09026.10 OAJ08410.1 - 0.46 10.9 35.0 0.09 13.2 6.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SMYLE_N PF18615.1 OAJ08410.1 - 0.62 9.6 4.7 0.81 9.2 4.7 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Utp14 PF04615.13 OAJ08410.1 - 1.7 7.2 22.7 0.059 12.0 6.5 2.3 2 0 0 2 2 2 0 Utp14 protein Voldacs PF03517.13 OAJ08410.1 - 2.4 8.3 11.5 7.1 6.7 2.5 2.5 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Nucleo_P87 PF07267.11 OAJ08410.1 - 3.8 6.2 11.0 0.75 8.6 4.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DUF3292 PF11696.8 OAJ08410.1 - 4.1 5.7 14.1 0.26 9.6 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) DUF4611 PF15387.6 OAJ08410.1 - 6.4 7.1 24.7 0.84 9.9 4.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) ADK_lid PF05191.14 OAJ08411.1 - 0.075 13.0 2.9 0.16 11.9 2.9 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid DIM PF08194.12 OAJ08411.1 - 0.97 9.7 6.0 4.4 7.6 0.6 2.6 2 0 0 2 2 2 0 DIM protein KAAG1 PF15354.6 OAJ08412.1 - 0.064 13.8 0.6 0.12 12.9 0.6 1.5 1 0 0 1 1 1 0 Kidney-associated antigen 1 MBOAT PF03062.19 OAJ08415.1 - 4.6e-47 161.1 1.6 4.8e-46 157.7 1.6 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RskA PF10099.9 OAJ08415.1 - 0.26 11.6 4.8 5.9 7.2 0.7 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RNase_T PF00929.24 OAJ08416.1 - 6.8e-08 33.2 0.0 4.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Exonuclease Pox_P21 PF05313.12 OAJ08425.1 - 1 8.9 6.3 1.1 8.8 6.3 1.0 1 0 0 1 1 1 0 Poxvirus P21 membrane protein PGM_PMM_I PF02878.16 OAJ08428.1 - 2.2e-36 124.6 0.1 3.4e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 OAJ08428.1 - 5.7e-28 97.4 0.0 1.6e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ08428.1 - 1.4e-14 54.5 0.0 4.6e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 OAJ08428.1 - 3.3e-06 27.2 0.0 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain mRNA_cap_enzyme PF01331.19 OAJ08429.1 - 4e-50 170.4 0.4 5.2e-50 170.0 0.4 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 OAJ08429.1 - 9.5e-26 90.6 0.0 1.6e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 OAJ08429.1 - 1e-07 31.8 0.0 5.6e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain FHA PF00498.26 OAJ08432.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 FHA domain bZIP_1 PF00170.21 OAJ08435.1 - 0.00012 22.1 9.7 0.00012 22.1 9.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor Kinesin_assoc PF16183.5 OAJ08435.1 - 0.00068 19.8 0.2 0.00068 19.8 0.2 2.8 3 0 0 3 3 3 1 Kinesin-associated Ino80_Iec3 PF14612.6 OAJ08435.1 - 0.016 15.9 0.5 0.016 15.9 0.5 3.0 2 1 1 3 3 3 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF702 PF05142.12 OAJ08435.1 - 2.5 8.6 9.2 2.2 8.8 3.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Roughex PF06020.11 OAJ08435.1 - 9.2 5.2 7.8 19 4.2 7.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CRPA PF05745.11 OAJ08439.1 - 0.3 11.1 1.5 0.53 10.3 1.5 1.4 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) YhfC PF10086.9 OAJ08440.1 - 0.028 13.8 0.6 0.049 13.0 0.6 1.3 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease MARVEL PF01284.23 OAJ08440.1 - 0.098 12.7 3.4 0.14 12.2 3.4 1.4 1 1 0 1 1 1 0 Membrane-associating domain DUF3648 PF12364.8 OAJ08440.1 - 0.11 12.7 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) PIF1 PF05970.14 OAJ08441.1 - 2.5e-46 158.5 0.0 2e-45 155.6 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ08441.1 - 7.1e-29 101.4 0.1 1.4e-28 100.4 0.1 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ08441.1 - 6e-11 42.4 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ08441.1 - 9e-05 22.8 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ08441.1 - 0.0027 17.6 0.0 0.046 13.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 OAJ08441.1 - 0.0096 15.7 0.2 2.1 8.0 0.1 3.0 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAJ08441.1 - 0.0098 16.3 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 OAJ08441.1 - 0.011 14.9 0.0 0.2 10.8 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 OAJ08441.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 OAJ08441.1 - 0.073 12.8 0.1 0.26 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ08441.1 - 0.083 12.9 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 OAJ08441.1 - 0.086 11.7 0.0 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 OAJ08441.1 - 0.096 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ08441.1 - 0.11 12.7 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF533 PF04391.12 OAJ08441.1 - 0.13 11.9 0.1 3.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) ResIII PF04851.15 OAJ08441.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RVT_1 PF00078.27 OAJ08443.1 - 3.5e-25 88.8 0.0 5.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08443.1 - 2.8e-14 52.9 0.0 4.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08443.1 - 0.0075 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08445.1 - 2e-15 56.7 0.0 3.2e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08445.1 - 5.2e-11 42.8 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ08445.1 - 8.6e-11 42.1 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08445.1 - 2.8e-05 24.1 0.0 6.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ08445.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger DUF5507 PF17612.2 OAJ08447.1 - 0.037 13.7 0.3 0.094 12.4 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5507) LIM PF00412.22 OAJ08451.1 - 2.9e-34 117.1 24.7 4.6e-14 52.4 3.1 5.0 5 0 0 5 5 5 4 LIM domain DUF2321 PF10083.9 OAJ08451.1 - 2.6 7.7 15.7 2.2 7.9 3.1 3.6 2 2 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2321) MARVEL PF01284.23 OAJ08452.1 - 6.3e-12 45.7 9.5 8.4e-12 45.3 9.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MTABC_N PF16185.5 OAJ08452.1 - 3.5 7.1 11.0 0.28 10.6 3.3 2.1 1 1 1 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region Snf7 PF03357.21 OAJ08453.1 - 8.9e-31 106.8 16.9 8.9e-31 106.8 16.9 1.4 2 0 0 2 2 2 1 Snf7 LPP PF04728.13 OAJ08453.1 - 0.34 11.3 3.3 2.7 8.5 1.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Vac14_Fig4_bd PF11916.8 OAJ08459.1 - 6.4e-75 250.7 6.4 6.4e-75 250.7 6.4 2.3 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 OAJ08459.1 - 1.9e-45 153.4 0.0 1.9e-40 137.3 0.0 4.1 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 OAJ08459.1 - 4.9e-15 54.3 1.4 0.00074 19.6 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 OAJ08459.1 - 6.7e-08 32.7 0.8 0.0016 18.5 0.5 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ08459.1 - 0.00011 22.5 13.7 1.8 9.0 0.2 6.3 5 1 0 6 6 5 2 HEAT repeats ParcG PF10274.9 OAJ08459.1 - 0.00034 20.8 0.5 0.098 12.8 0.1 3.1 4 0 0 4 4 4 1 Parkin co-regulated protein CLASP_N PF12348.8 OAJ08459.1 - 0.0011 18.6 0.2 5.3 6.5 0.0 4.1 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 OAJ08459.1 - 0.0014 19.1 15.8 0.074 13.6 0.0 7.2 9 0 0 9 9 8 2 HEAT-like repeat DUF3385 PF11865.8 OAJ08459.1 - 0.026 14.4 0.2 1.5 8.7 0.0 3.7 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Dopey_N PF04118.14 OAJ08459.1 - 0.032 13.4 0.1 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Dopey, N-terminal Tti2 PF10521.9 OAJ08459.1 - 0.045 13.3 1.5 18 4.7 0.0 3.9 4 1 1 5 5 5 0 Tti2 family Arm PF00514.23 OAJ08459.1 - 1.7 8.8 6.1 14 5.9 0.0 5.4 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Brr6_like_C_C PF10104.9 OAJ08464.1 - 6.8e-08 32.4 0.0 8.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ribosomal_L2_C PF03947.18 OAJ08469.1 - 3.9e-49 166.0 6.3 2.2e-48 163.6 6.3 2.4 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 OAJ08469.1 - 3.2e-25 87.9 0.1 7.2e-25 86.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PrpF PF04303.13 OAJ08470.1 - 1e-47 162.9 0.2 1.5e-33 116.3 0.0 2.5 2 1 0 2 2 2 2 PrpF protein SAT PF16073.5 OAJ08470.1 - 0.074 12.8 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Peptidase_S8 PF00082.22 OAJ08474.1 - 3.7e-21 75.7 0.1 5.4e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Subtilase family RVT_1 PF00078.27 OAJ08478.1 - 5.3e-24 85.0 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08478.1 - 1.8e-20 72.8 0.1 4.2e-13 49.2 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08478.1 - 1.5e-14 53.8 0.0 4e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ08478.1 - 4.8e-14 52.5 0.0 1.3e-09 38.3 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08478.1 - 3.1e-10 40.3 0.0 1.4e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ08478.1 - 0.0001 22.4 0.0 0.023 14.9 0.0 2.8 2 0 0 2 2 2 1 H2C2 zinc finger Prefoldin_2 PF01920.20 OAJ08481.1 - 3.3e-23 81.7 0.6 3.9e-23 81.4 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 OAJ08481.1 - 6.2e-05 22.7 2.1 0.085 12.6 0.0 2.2 1 1 1 2 2 2 2 Septum formation initiator SesA PF17107.5 OAJ08481.1 - 0.0037 17.4 0.2 1.3 9.3 0.1 2.1 2 0 0 2 2 2 2 N-terminal domain on NACHT_NTPase and P-loop NTPases ADIP PF11559.8 OAJ08481.1 - 0.0052 16.9 0.9 2.6 8.1 0.0 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Prefoldin PF02996.17 OAJ08481.1 - 0.03 14.2 0.9 0.06 13.3 0.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit KASH_CCD PF14662.6 OAJ08481.1 - 0.044 13.6 3.5 0.085 12.7 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc24 PF08286.11 OAJ08481.1 - 0.055 13.7 3.2 3.9 7.8 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Lipoprotein_18 PF06804.11 OAJ08481.1 - 0.058 12.4 0.3 0.069 12.2 0.3 1.1 1 0 0 1 1 1 0 NlpB/DapX lipoprotein DUF4164 PF13747.6 OAJ08481.1 - 0.068 13.5 4.7 2.9 8.2 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) SlyX PF04102.12 OAJ08481.1 - 0.11 13.1 2.2 4.8 7.9 0.0 2.4 2 1 0 2 2 2 0 SlyX DHR10 PF18595.1 OAJ08481.1 - 0.15 12.2 4.3 2 8.5 0.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 OAJ08481.1 - 0.24 11.4 1.5 1.6 8.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAJ08481.1 - 0.4 9.5 4.0 2.8 6.7 4.0 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Cue1_U7BR PF18499.1 OAJ08482.1 - 0.034 14.2 2.8 0.067 13.2 2.8 1.4 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 DUF4834 PF16118.5 OAJ08482.1 - 1.3 10.0 3.3 2.9 8.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) CoA_binding PF02629.19 OAJ08483.1 - 7.6e-29 100.3 1.7 4e-28 97.9 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 OAJ08483.1 - 1.2e-19 70.6 0.6 2.6e-19 69.5 0.6 1.6 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 OAJ08483.1 - 4e-09 36.4 0.1 8.9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain GFO_IDH_MocA PF01408.22 OAJ08483.1 - 0.053 14.3 0.0 0.22 12.4 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DUF3844 PF12955.7 OAJ08484.1 - 4.4e-26 91.1 0.2 8.4e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Internalin_N PF12354.8 OAJ08484.1 - 0.55 10.3 4.7 0.53 10.4 0.8 2.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal DDE_Tnp_4 PF13359.6 OAJ08488.1 - 1.2e-24 86.7 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ08488.1 - 1.7e-07 31.1 0.0 2.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ08488.1 - 3.1e-05 23.7 0.0 6.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ08488.1 - 0.031 14.6 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain Myb_DNA-bind_3 PF12776.7 OAJ08489.1 - 1.9e-14 54.4 0.7 3.1e-14 53.7 0.7 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ08489.1 - 3.1e-05 24.3 1.2 0.00018 21.8 1.2 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain PI3K_1B_p101 PF10486.9 OAJ08493.1 - 0.029 12.2 3.1 0.07 10.9 3.1 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.6 OAJ08493.1 - 1.1 9.7 11.5 0.78 10.2 5.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.16 OAJ08494.1 - 3.7e-10 39.9 1.0 3.7e-10 39.9 1.0 1.4 2 0 0 2 2 2 1 TLC domain E1-E2_ATPase PF00122.20 OAJ08497.1 - 4.2e-47 160.0 2.9 7.9e-47 159.1 2.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ08497.1 - 1.6e-30 107.0 0.8 1.1e-23 84.7 0.1 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 OAJ08497.1 - 3.9e-20 72.1 0.0 1.3e-11 44.8 0.0 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.7 OAJ08497.1 - 0.00092 19.7 0.1 0.0037 17.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ08497.1 - 0.022 14.5 0.4 0.071 12.8 0.7 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4006 PF13179.6 OAJ08497.1 - 0.18 11.7 0.2 0.46 10.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF1656 PF07869.12 OAJ08497.1 - 3.5 7.7 7.7 4.3 7.4 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Aminotran_3 PF00202.21 OAJ08502.1 - 4.9e-90 302.1 0.0 7e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DAO PF01266.24 OAJ08503.1 - 1.4e-53 182.8 2.4 1.6e-53 182.6 2.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ08503.1 - 3.3e-06 27.6 0.2 0.026 15.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ08503.1 - 5.3e-05 22.6 0.2 0.0041 16.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ08503.1 - 0.00044 20.4 1.5 0.0011 19.2 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ08503.1 - 0.0043 16.3 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 OAJ08503.1 - 0.035 13.4 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 OAJ08503.1 - 0.052 12.4 0.3 0.52 9.1 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 OAJ08503.1 - 0.16 12.2 0.2 0.42 10.9 0.2 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 OAJ08503.1 - 0.22 11.5 0.7 0.43 10.6 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Chlam_vir PF05475.11 OAJ08504.1 - 0.029 14.1 0.7 0.035 13.8 0.7 1.2 1 0 0 1 1 1 0 Pgp3 C-terminal domain Sporozoite_P67 PF05642.11 OAJ08504.1 - 4.5 5.2 13.9 4.8 5.1 13.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Clathrin_propel PF01394.20 OAJ08507.1 - 2.1e-21 75.1 1.9 6.5e-07 29.4 0.1 4.6 4 1 0 4 4 4 4 Clathrin propeller repeat NUP214 PF16755.5 OAJ08507.1 - 0.0051 16.1 0.1 0.0068 15.7 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 RNA_polI_A34 PF08208.11 OAJ08508.1 - 1.7 8.7 26.9 2.4 8.2 7.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.29 OAJ08509.1 - 7.4e-43 146.1 0.0 1.2e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ08509.1 - 9.3e-12 44.6 0.1 2.4e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 OAJ08509.1 - 1.4e-10 41.0 0.1 3.2e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ08509.1 - 2.5e-07 30.8 0.0 3.3e-06 27.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ08509.1 - 6.7e-07 29.9 0.0 0.00023 21.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ08509.1 - 1.8e-06 28.2 0.0 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 OAJ08509.1 - 9.7e-06 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ08509.1 - 0.00016 21.9 0.2 0.005 17.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 OAJ08509.1 - 0.00049 20.7 0.0 0.0036 17.9 0.0 2.3 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 OAJ08509.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ08509.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ08509.1 - 0.0034 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ08509.1 - 0.0043 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ08509.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ08509.1 - 0.0078 16.4 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ08509.1 - 0.0081 15.9 0.2 0.044 13.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 OAJ08509.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAJ08509.1 - 0.0097 15.6 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 OAJ08509.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ08509.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAJ08509.1 - 0.014 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 OAJ08509.1 - 0.029 14.1 0.5 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ08509.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAJ08509.1 - 0.033 14.4 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ08509.1 - 0.046 13.1 0.1 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ08509.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ08509.1 - 0.069 12.7 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ08509.1 - 0.099 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain CPT PF07931.12 OAJ08509.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Phage_tail_APC PF16778.5 OAJ08509.1 - 0.22 11.4 0.5 0.68 9.8 0.1 2.0 2 0 0 2 2 1 0 Phage tail assembly chaperone protein DUF4200 PF13863.6 OAJ08509.1 - 0.49 10.8 3.6 0.21 12.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_23 PF13476.6 OAJ08509.1 - 0.87 10.0 5.2 11 6.5 0.2 2.5 2 1 0 2 2 2 0 AAA domain Sec23_trunk PF04811.15 OAJ08512.1 - 6.2e-71 238.8 0.0 1e-70 238.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 OAJ08512.1 - 3.1e-16 59.1 8.1 6.1e-16 58.2 8.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 OAJ08512.1 - 5.4e-16 58.3 0.3 1.5e-15 56.9 0.2 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAJ08512.1 - 1.3e-15 57.9 0.0 3.7e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 OAJ08512.1 - 0.0073 15.7 2.3 0.014 14.7 2.3 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain RT_RNaseH PF17917.1 OAJ08513.1 - 2.3e-11 43.9 0.0 4.1e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08513.1 - 2.5e-05 24.3 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08514.1 - 4.8e-25 88.4 0.0 8.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08514.1 - 1.4e-15 57.1 0.3 2.6e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08514.1 - 4.7e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08514.1 - 8.7e-10 38.8 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ08514.1 - 0.00021 21.9 0.0 0.00057 20.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ08514.1 - 0.0068 16.7 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ08514.1 - 0.041 14.4 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF1772 PF08592.11 OAJ08516.1 - 3.3 8.0 12.3 0.35 11.2 2.1 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DHHA2 PF02833.14 OAJ08519.1 - 0.00089 19.5 0.0 0.00089 19.5 0.0 1.1 1 0 0 1 1 1 1 DHHA2 domain Phage_integrase PF00589.22 OAJ08520.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF3008 PF11450.8 OAJ08525.1 - 0.032 14.4 2.4 5 7.4 0.9 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Dak2 PF02734.17 OAJ08525.1 - 0.049 13.5 0.4 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 DAK2 domain Methyltransf_11 PF08241.12 OAJ08529.1 - 2e-10 41.2 0.0 1.1e-08 35.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ08529.1 - 2.9e-09 37.5 0.0 0.00069 20.3 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ08529.1 - 8.5e-06 26.4 0.0 0.0047 17.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ08529.1 - 0.033 14.0 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FHA PF00498.26 OAJ08530.1 - 0.055 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 FHA domain RVT_1 PF00078.27 OAJ08533.1 - 7.7e-13 48.5 0.0 1.9e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ08533.1 - 0.0022 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ08533.1 - 0.13 12.4 3.6 0.062 13.4 1.2 1.7 2 0 0 2 2 2 0 Zinc knuckle P_C10 PF14974.6 OAJ08533.1 - 0.17 12.0 0.0 0.53 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein C10 Integrase_H2C2 PF17921.1 OAJ08534.1 - 3.6e-21 75.0 0.5 3.6e-21 75.0 0.5 1.5 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 OAJ08534.1 - 0.0016 18.6 0.1 0.0039 17.4 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag_pre-integrs PF13976.6 OAJ08534.1 - 0.061 13.2 0.1 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 GAG-pre-integrase domain BIR PF00653.21 OAJ08548.1 - 7.2e-29 100.3 3.0 6.5e-21 74.8 1.9 3.0 2 1 0 2 2 2 2 Inhibitor of Apoptosis domain Tfb4 PF03850.14 OAJ08548.1 - 0.22 11.0 4.7 0.5 9.8 4.7 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 Lin-8 PF03353.15 OAJ08548.1 - 0.71 9.4 17.6 2.1 7.9 17.6 1.8 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 OAJ08548.1 - 5.8 4.6 12.2 9.9 3.8 12.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit UMP1 PF05348.11 OAJ08550.1 - 5.9e-29 100.7 1.2 7.5e-29 100.4 1.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF3435 PF11917.8 OAJ08553.1 - 0.63 8.9 6.9 0.85 8.5 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) S4_2 PF13275.6 OAJ08554.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 S4 domain UCMA PF17085.5 OAJ08558.1 - 0.034 14.2 5.8 0.084 12.9 5.8 1.7 1 0 0 1 1 1 0 Unique cartilage matrix associated protein SPT2 PF08243.11 OAJ08558.1 - 0.89 10.1 27.6 0.055 14.0 20.5 2.3 1 1 1 2 2 2 0 SPT2 chromatin protein TFIIA PF03153.13 OAJ08558.1 - 1.7 8.6 17.0 2 8.3 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.13 OAJ08558.1 - 3.2 7.4 18.4 4.3 7.0 18.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 OAJ08558.1 - 7.5 4.7 19.6 12 4.1 19.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SOAR PF16533.5 OAJ08559.1 - 0.095 12.7 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region FYVE PF01363.21 OAJ08560.1 - 3.4e-15 55.9 8.9 4.4e-15 55.6 8.9 1.2 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OAJ08560.1 - 0.029 14.6 7.6 0.071 13.3 7.6 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 OAJ08560.1 - 0.71 10.1 9.3 0.16 12.1 2.2 2.4 3 0 0 3 3 3 0 B-box zinc finger HypA PF01155.19 OAJ08560.1 - 2 8.5 7.3 1.9 8.5 2.9 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_11 PF17123.5 OAJ08561.1 - 0.00013 21.7 0.9 0.00025 20.7 0.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAJ08561.1 - 0.015 15.6 0.2 0.028 14.8 0.2 1.4 1 0 0 1 1 1 0 Ring finger domain MFS_1 PF07690.16 OAJ08566.1 - 5.4e-26 91.4 34.2 3.3e-17 62.4 11.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ08566.1 - 2.3e-14 53.1 4.4 2.3e-14 53.1 4.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Utp12 PF04003.12 OAJ08570.1 - 0.0012 19.1 0.8 0.0018 18.6 0.8 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Helicase_C PF00271.31 OAJ08571.1 - 4.9e-11 42.9 0.0 2e-08 34.6 0.0 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RR_TM4-6 PF06459.12 OAJ08571.1 - 0.6 9.9 2.8 1 9.1 2.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rrn6 PF10214.9 OAJ08571.1 - 1.5 7.2 4.8 2.1 6.7 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DHHC PF01529.20 OAJ08574.1 - 1.5e-34 118.9 5.4 1.5e-34 118.9 5.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 OAJ08574.1 - 0.45 10.7 3.1 1.1 9.4 3.1 1.7 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Voldacs PF03517.13 OAJ08575.1 - 6.7e-18 65.1 0.0 8.4e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Skp1_POZ PF03931.15 OAJ08576.1 - 0.00055 20.1 0.0 0.0036 17.4 0.0 2.0 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain UPF0489 PF12640.7 OAJ08579.1 - 0.12 12.6 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 UPF0489 domain RT_RNaseH_2 PF17919.1 OAJ08582.1 - 1.3e-32 111.8 0.0 3.4e-32 110.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08582.1 - 2.2e-28 98.6 0.0 4.3e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08582.1 - 1.3e-19 70.6 0.0 2.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4336 PF14234.6 OAJ08582.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Tho1_MOS11_C PF18592.1 OAJ08583.1 - 0.16 11.8 1.6 2.5 8.0 0.2 2.4 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Serpentine_r_xa PF03383.15 OAJ08592.1 - 0.047 13.7 2.3 0.099 12.6 0.8 2.1 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa SelK_SelG PF10961.8 OAJ08592.1 - 0.25 12.0 1.8 2 9.1 0.1 3.0 3 0 0 3 3 3 0 Selenoprotein SelK_SelG Calcipressin PF04847.12 OAJ08595.1 - 4.3e-24 85.3 0.0 2.8e-20 72.9 0.4 2.3 2 0 0 2 2 2 2 Calcipressin Septin PF00735.18 OAJ08596.1 - 1.6e-114 382.0 0.4 2.1e-114 381.6 0.4 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ08596.1 - 2.4e-09 37.2 0.0 6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ08596.1 - 4.7e-08 33.1 0.2 1.1e-06 28.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ08596.1 - 1.2e-06 28.2 3.2 5.9e-05 22.7 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 OAJ08596.1 - 3.4e-05 24.1 0.2 7.9e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ08596.1 - 5.5e-05 22.8 0.6 0.00017 21.2 0.6 1.9 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 OAJ08596.1 - 0.00038 20.9 1.1 0.00055 20.4 0.2 2.0 2 1 0 2 2 1 1 AAA ATPase domain AIG1 PF04548.16 OAJ08596.1 - 0.00048 19.5 0.0 0.001 18.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 OAJ08596.1 - 0.00061 20.1 1.8 0.0011 19.3 0.2 2.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 OAJ08596.1 - 0.0013 19.3 0.1 0.0041 17.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 OAJ08596.1 - 0.0028 17.4 1.6 0.049 13.4 0.2 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 OAJ08596.1 - 0.0061 15.9 0.1 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 OAJ08596.1 - 0.015 14.9 0.1 0.042 13.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 OAJ08596.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 OAJ08596.1 - 0.018 14.6 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 OAJ08596.1 - 0.018 14.8 0.6 2.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 OAJ08596.1 - 0.026 14.6 4.7 0.57 10.2 0.2 2.8 2 1 1 3 3 3 0 Dynamin family NB-ARC PF00931.22 OAJ08596.1 - 0.028 13.6 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 OAJ08596.1 - 0.059 13.4 0.6 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OAJ08596.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 OAJ08596.1 - 0.072 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 OAJ08596.1 - 0.074 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 OAJ08596.1 - 0.091 13.2 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 OAJ08596.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 OAJ08596.1 - 0.11 12.3 6.5 0.11 12.2 0.9 2.6 2 1 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 OAJ08596.1 - 0.11 13.2 0.5 0.4 11.4 0.5 2.0 1 0 0 1 1 1 0 FOXP coiled-coil domain cobW PF02492.19 OAJ08596.1 - 0.55 9.8 5.7 0.7 9.5 0.5 2.6 2 1 1 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 OAJ08596.1 - 0.67 9.1 4.3 3.9 6.5 4.3 2.4 1 1 0 1 1 1 0 G-protein alpha subunit CHCH PF06747.13 OAJ08597.1 - 9.4e-05 22.4 1.1 0.00013 22.0 1.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 OAJ08597.1 - 0.00018 21.5 0.5 0.00021 21.2 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 OAJ08597.1 - 0.071 13.5 0.6 1.3 9.4 0.1 1.8 1 1 1 2 2 2 0 GCK domain Polysacc_deac_1 PF01522.21 OAJ08600.1 - 1.1e-16 60.8 0.0 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase SLATT_1 PF18181.1 OAJ08601.1 - 0.072 13.0 1.2 0.22 11.5 1.2 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DEAD PF00270.29 OAJ08605.1 - 4.5e-39 134.0 0.1 9.4e-39 133.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ08605.1 - 9.8e-22 77.4 0.0 1.1e-20 74.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ08605.1 - 3.4e-05 23.9 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ08605.1 - 0.21 10.8 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HRXXH PF13933.6 OAJ08606.1 - 3.5e-75 252.7 0.0 4.1e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 OAJ08606.1 - 0.042 14.4 0.2 0.12 12.9 0.1 1.8 1 1 1 2 2 2 0 Lysine-specific metallo-endopeptidase MVL PF12151.8 OAJ08606.1 - 0.15 11.9 2.7 0.33 10.8 2.7 1.5 1 0 0 1 1 1 0 Mannan-binding protein Methyltransf_15 PF09445.10 OAJ08608.1 - 2.1e-32 112.0 0.0 1.7e-26 92.7 0.0 2.4 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 OAJ08608.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 OAJ08608.1 - 4.3e-06 27.4 0.1 1.1e-05 26.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAJ08608.1 - 0.001 18.8 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 OAJ08608.1 - 0.0026 16.9 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 OAJ08608.1 - 0.0099 16.5 0.0 0.023 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ08608.1 - 0.01 15.2 1.9 0.013 14.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 OAJ08608.1 - 0.04 13.6 0.0 0.04 13.6 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical protein 95 TRM PF02005.16 OAJ08608.1 - 0.052 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 OAJ08608.1 - 0.066 12.2 0.0 0.066 12.2 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 OAJ08608.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Lin-8 PF03353.15 OAJ08608.1 - 2.3 7.7 13.5 0.16 11.5 8.2 1.7 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SLC12 PF03522.15 OAJ08608.1 - 3.7 6.5 9.0 5.9 5.8 9.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SelP_N PF04592.14 OAJ08608.1 - 7 6.0 13.7 13 5.1 13.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Suf PF05843.14 OAJ08608.1 - 7.3 6.5 16.8 4.3 7.2 14.4 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) NEMP PF10225.9 OAJ08608.1 - 9 5.9 5.0 17 5.0 5.0 1.3 1 0 0 1 1 1 0 NEMP family Transposase_21 PF02992.14 OAJ08614.1 - 4.2e-19 68.6 0.0 7.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 SlyX PF04102.12 OAJ08615.1 - 0.14 12.8 3.0 14 6.4 0.0 3.2 3 0 0 3 3 3 0 SlyX UTP25 PF06862.12 OAJ08619.1 - 4.4e-106 355.5 0.0 7.6e-106 354.7 0.0 1.4 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AICARFT_IMPCHas PF01808.18 OAJ08620.1 - 4e-84 282.6 0.3 5.6e-84 282.1 0.3 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 OAJ08620.1 - 1.4e-21 76.5 0.0 2.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain MFS_1 PF07690.16 OAJ08623.1 - 4e-14 52.3 53.5 9.9e-14 51.0 43.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 OAJ08623.1 - 0.14 12.2 0.3 0.53 10.4 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Peptidase_S15 PF02129.18 OAJ08628.1 - 6.6 6.2 15.8 53 3.3 0.1 2.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Pal1 PF08316.11 OAJ08628.1 - 7.8 7.3 15.6 20 5.9 0.0 3.8 3 0 0 3 3 3 0 Pal1 cell morphology protein A_deamin PF02137.18 OAJ08636.1 - 1.1e-25 90.9 0.0 2.4e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2207 PF09972.9 OAJ08637.1 - 7.7 5.2 6.4 8.2 5.1 6.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RVT_2 PF07727.14 OAJ08646.1 - 3.8e-69 233.0 0.0 5.4e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08646.1 - 8e-14 51.8 0.0 4.7e-13 49.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08646.1 - 7.4e-07 28.9 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C2H2_10 PF16588.5 OAJ08647.1 - 0.6 9.9 2.9 0.97 9.2 2.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Amidase PF01425.21 OAJ08653.1 - 3.9e-93 312.9 0.0 9.7e-93 311.6 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF455 PF04305.14 OAJ08654.1 - 7.5e-93 310.6 0.0 9.8e-93 310.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 OAJ08654.1 - 3.2e-08 33.4 0.8 1.2e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 OAJ08654.1 - 0.0019 18.1 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain Histone PF00125.24 OAJ08659.1 - 8.7e-47 158.8 1.8 9.7e-47 158.6 1.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ08659.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ08659.1 - 3.8e-05 23.8 0.7 5.2e-05 23.3 0.2 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ08659.1 - 0.041 14.2 1.5 0.17 12.2 0.1 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAJ08659.1 - 0.062 13.9 0.9 0.075 13.6 0.9 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Tfb2 PF03849.14 OAJ08660.1 - 8.6e-17 61.1 0.0 1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 OrfB_Zn_ribbon PF07282.11 OAJ08666.1 - 0.00045 20.1 1.0 0.015 15.2 1.0 2.5 1 1 0 1 1 1 1 Putative transposase DNA-binding domain DUF3932 PF13068.6 OAJ08666.1 - 0.012 15.8 0.1 1.8 8.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) BORCS8 PF10167.9 OAJ08666.1 - 0.017 15.0 1.1 0.028 14.3 0.2 1.8 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 RVT_1 PF00078.27 OAJ08674.1 - 0.0038 16.8 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Phage_integrase PF00589.22 OAJ08675.1 - 0.031 14.1 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family RT_RNaseH_2 PF17919.1 OAJ08679.1 - 2.5e-32 110.9 0.0 6.1e-32 109.6 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08679.1 - 8.8e-28 96.7 0.0 2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08679.1 - 6.2e-20 71.7 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08679.1 - 0.024 14.8 1.2 0.057 13.5 1.2 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain zf-CCHC PF00098.23 OAJ08679.1 - 0.044 13.9 7.0 0.017 15.2 4.3 1.8 2 0 0 2 2 2 0 Zinc knuckle rve PF00665.26 OAJ08680.1 - 1.5e-15 57.5 0.0 2.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ08680.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Pkinase PF00069.25 OAJ08684.1 - 7.4e-72 241.9 0.0 9.9e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08684.1 - 1e-28 100.4 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ08684.1 - 5.7e-08 32.4 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ08684.1 - 3.4e-05 22.8 0.0 5.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ08684.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NtA PF03146.15 OAJ08684.1 - 0.039 13.8 0.1 0.12 12.2 0.1 1.8 2 0 0 2 2 2 0 Agrin NtA domain APH PF01636.23 OAJ08684.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF677 PF05055.12 OAJ08688.1 - 0.074 11.9 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Glyco_transf_20 PF00982.21 OAJ08689.1 - 2.7e-54 184.6 0.0 1.4e-46 159.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 SARAF PF06682.12 OAJ08689.1 - 0.047 13.3 0.6 0.068 12.8 0.6 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Serglycin PF04360.12 OAJ08689.1 - 0.28 11.1 10.1 0.058 13.3 4.5 2.2 2 0 0 2 2 2 0 Serglycin RVT_2 PF07727.14 OAJ08694.1 - 1.4e-71 240.9 0.0 2.5e-71 240.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08694.1 - 2.1e-19 69.9 0.3 8.3e-19 67.9 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ08694.1 - 1.1e-05 25.1 0.0 3.6e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ08694.1 - 0.00039 20.1 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 OAJ08695.1 - 0.00027 20.9 1.8 0.0007 19.5 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ08695.1 - 0.0012 18.5 4.5 0.0024 17.6 3.4 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 OAJ08695.1 - 0.0022 18.0 1.5 0.0037 17.3 1.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ08695.1 - 0.017 14.9 0.9 0.027 14.3 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle KDZ PF18758.1 OAJ08704.1 - 0.0058 16.3 0.7 0.0098 15.5 0.7 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TP_methylase PF00590.20 OAJ08710.1 - 2.9e-34 118.9 0.2 5.3e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 OAJ08710.1 - 3.2e-11 42.4 0.4 6.7e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 OAJ08710.1 - 5.2e-08 33.3 0.0 0.00021 21.7 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ08710.1 - 1e-07 31.5 0.0 7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Herpes_pp85 PF04637.12 OAJ08710.1 - 0.23 9.9 0.2 0.48 8.8 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Asp_protease_2 PF13650.6 OAJ08716.1 - 0.005 17.5 0.0 0.58 10.8 0.0 2.5 3 0 0 3 3 3 2 Aspartyl protease RVT_2 PF07727.14 OAJ08718.1 - 8.1e-70 235.2 0.0 1.2e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ08719.1 - 3.3e-06 26.9 2.4 7.5e-06 25.8 2.4 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ08719.1 - 0.0064 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 OAJ08719.1 - 0.67 9.7 2.1 0.65 9.8 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle Prenylcys_lyase PF07156.14 OAJ08725.1 - 2e-62 211.4 0.0 2e-60 204.8 0.0 2.8 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 OAJ08725.1 - 1e-10 41.7 0.1 5.9e-10 39.2 0.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ08725.1 - 8.1e-06 25.3 0.1 1.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ08725.1 - 4.9e-05 23.1 0.2 0.0001 22.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ08725.1 - 0.00026 21.0 0.3 0.005 16.8 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 OAJ08725.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 OAJ08725.1 - 0.0082 15.5 1.1 0.012 15.0 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ08725.1 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 OAJ08725.1 - 0.015 14.2 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 OAJ08725.1 - 0.016 14.3 0.9 0.016 14.3 0.9 1.6 2 0 0 2 2 2 0 FAD binding domain TAFII28 PF04719.14 OAJ08725.1 - 0.038 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region HI0933_like PF03486.14 OAJ08725.1 - 0.041 12.6 0.1 0.058 12.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAJ08725.1 - 0.25 10.4 3.5 0.5 9.4 1.3 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lactonase PF10282.9 OAJ08726.1 - 9e-18 64.6 0.0 6.2e-17 61.9 0.0 1.9 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller HMG_box PF00505.19 OAJ08729.1 - 5.4e-08 33.1 0.7 1.3e-07 31.9 1.1 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box Macoilin PF09726.9 OAJ08733.1 - 0.96 7.9 4.0 1.4 7.4 4.0 1.1 1 0 0 1 1 1 0 Macoilin family Exo_endo_phos_2 PF14529.6 OAJ08734.1 - 3e-10 40.0 0.0 1.5e-09 37.7 0.0 2.3 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ08734.1 - 4.9e-07 29.5 0.4 4.5e-06 26.4 0.1 2.5 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SRP54 PF00448.22 OAJ08734.1 - 0.029 14.0 0.0 0.061 12.9 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ICL PF00463.21 OAJ08742.1 - 0.00013 20.6 0.0 0.00013 20.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Phage_integrase PF00589.22 OAJ08743.1 - 6.2e-05 22.9 0.0 7.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF1308 PF07000.11 OAJ08746.1 - 0.00046 20.2 0.1 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1308) Pkinase PF00069.25 OAJ08747.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ08747.1 - 0.17 11.1 0.0 0.65 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DUF866 PF05907.13 OAJ08755.1 - 4.9e-48 162.9 0.6 5.6e-48 162.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF1272 PF06906.11 OAJ08755.1 - 0.052 13.6 2.1 0.23 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DDE_3 PF13358.6 OAJ08759.1 - 9.7e-08 31.9 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Abhydrolase_6 PF12697.7 OAJ08764.1 - 1.5e-09 38.8 0.9 2.6e-09 38.0 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ08764.1 - 1.2e-07 31.3 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ08764.1 - 1.4e-07 31.4 0.1 2.4e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2_10 PF16588.5 OAJ08768.1 - 5 6.9 6.7 0.5 10.2 1.0 2.2 2 0 0 2 2 2 0 C2H2 zinc-finger Asp_protease_2 PF13650.6 OAJ08773.1 - 6.2e-05 23.6 0.0 0.00019 22.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08773.1 - 0.001 19.6 0.0 0.004 17.7 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF2849 PF11011.8 OAJ08773.1 - 0.026 15.2 0.1 0.76 10.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Zn_protease PF05618.11 OAJ08773.1 - 0.043 13.7 1.0 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 Putative ATP-dependant zinc protease dUTPase PF00692.19 OAJ08773.1 - 0.083 12.6 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 dUTPase RVT_1 PF00078.27 OAJ08774.1 - 2e-23 83.1 0.0 3.6e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08774.1 - 1e-16 60.7 0.0 1.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08774.1 - 3.7e-15 55.8 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ08774.1 - 0.00024 21.3 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ08774.1 - 0.0029 17.9 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Exc PF07825.11 OAJ08774.1 - 0.36 10.9 2.8 0.39 10.7 0.6 2.1 2 0 0 2 2 2 0 Excisionase-like protein G-patch PF01585.23 OAJ08777.1 - 7.4e-10 38.6 8.1 1.1e-09 38.0 3.3 2.4 2 1 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ08777.1 - 0.00017 21.6 1.9 0.00031 20.7 1.8 1.6 1 1 1 2 2 2 1 G-patch domain DAP3 PF10236.9 OAJ08778.1 - 2e-37 129.1 0.0 7.5e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 OAJ08778.1 - 2.7e-05 24.6 0.7 5.9e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ08778.1 - 0.0069 16.7 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain GTP1_OBG PF01018.22 OAJ08779.1 - 1.4e-41 141.7 0.8 3.1e-29 101.6 1.7 3.4 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 OAJ08779.1 - 2.6e-18 66.2 0.0 6e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ08779.1 - 0.00035 20.1 0.2 0.00069 19.2 0.2 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TFIIE_alpha PF02002.17 OAJ08779.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit ABC_tran PF00005.27 OAJ08779.1 - 0.18 12.3 0.8 0.5 10.9 0.1 2.1 2 0 0 2 2 2 0 ABC transporter UBN_AB PF14075.6 OAJ08779.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Fe-ADH_2 PF13685.6 OAJ08779.1 - 0.24 11.1 1.2 1.3 8.6 0.2 2.3 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase CPSase_L_D2 PF02786.17 OAJ08782.1 - 0.00044 19.8 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain YuzL PF14115.6 OAJ08784.1 - 0.26 11.8 3.3 0.51 10.9 3.3 1.4 1 0 0 1 1 1 0 YuzL-like protein CPSase_L_D2 PF02786.17 OAJ08785.1 - 5.6e-64 215.5 0.0 6.2e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OAJ08785.1 - 1.8e-07 30.9 0.0 2.1e-07 30.6 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 OAJ08785.1 - 9e-05 22.1 0.0 0.00031 20.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 OAJ08785.1 - 0.00029 20.9 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 OAJ08785.1 - 0.0028 17.1 0.2 0.0046 16.4 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 OAJ08785.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 OAJ08786.1 - 0.076 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain Epimerase PF01370.21 OAJ08786.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HsbA PF12296.8 OAJ08789.1 - 2.2e-18 66.8 10.4 2.2e-18 66.8 10.4 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A GCN5L1 PF06320.13 OAJ08789.1 - 0.11 12.7 1.6 0.22 11.6 0.4 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF1307 PF06998.11 OAJ08789.1 - 0.14 12.2 2.8 6.8 6.7 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1307) HsbA PF12296.8 OAJ08790.1 - 4.5e-18 65.8 14.0 5.5e-18 65.5 14.0 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A PIN_12 PF16289.5 OAJ08790.1 - 0.026 15.0 0.1 0.035 14.6 0.1 1.2 1 0 0 1 1 1 0 PIN domain Syntaxin-6_N PF09177.11 OAJ08790.1 - 0.11 13.0 0.3 0.15 12.6 0.3 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal YnfE PF17452.2 OAJ08790.1 - 0.13 12.5 0.3 0.21 11.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized YnfE-like Cupin_8 PF13621.6 OAJ08791.1 - 5e-25 88.7 0.0 1.5e-24 87.1 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 OAJ08791.1 - 3.9e-08 33.1 0.1 4e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 OAJ08791.1 - 1.5e-05 25.4 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 OAJ08791.1 - 0.042 13.6 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Cupin domain Snf7 PF03357.21 OAJ08794.1 - 1.6e-37 128.7 15.5 2.7e-37 128.0 15.5 1.3 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 OAJ08794.1 - 0.061 12.9 16.8 0.15 11.6 5.5 2.1 1 1 1 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 OAJ08794.1 - 0.17 11.9 9.2 0.62 10.1 8.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 OAJ08794.1 - 0.31 10.9 3.2 15 5.5 0.1 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor YlqD PF11068.8 OAJ08794.1 - 1.1 9.6 12.7 3.1 8.2 10.0 2.1 1 1 1 2 2 2 0 YlqD protein OmpH PF03938.14 OAJ08794.1 - 4.3 7.7 14.3 1.9 8.8 2.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GAS PF13851.6 OAJ08794.1 - 7 5.9 11.0 1.2 8.4 2.6 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADK PF00406.22 OAJ08795.1 - 2.7e-44 150.9 0.1 2.3e-23 83.0 0.0 2.1 1 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 OAJ08795.1 - 5.1e-34 117.6 0.4 6.5e-32 110.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ08795.1 - 4.3e-12 46.7 0.0 7.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 OAJ08795.1 - 3.4e-07 30.1 0.2 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 OAJ08795.1 - 0.0014 18.8 0.0 0.0082 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ08795.1 - 0.032 13.5 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 OAJ08795.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 OAJ08795.1 - 0.18 12.2 0.3 0.28 11.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain zf-CHCC PF10276.9 OAJ08796.1 - 1.1e-17 63.7 1.5 1.7e-17 63.1 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain RVT_1 PF00078.27 OAJ08804.1 - 2.9e-24 85.8 0.0 4.9e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ08804.1 - 2.4e-14 53.2 0.0 4.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ08804.1 - 1.2e-12 48.0 0.0 2.7e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08804.1 - 3.3e-10 40.2 0.0 6.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ08804.1 - 3.7e-07 30.1 0.4 1.9e-05 24.6 0.0 2.8 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ08804.1 - 3.8e-06 27.5 0.1 1.3e-05 25.7 0.1 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ08804.1 - 0.00086 19.8 0.0 0.0021 18.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ08804.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 OAJ08804.1 - 0.12 12.7 0.0 0.36 11.2 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease Med3 PF11593.8 OAJ08805.1 - 1.5 7.9 10.9 1.6 7.9 10.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-U1 PF06220.12 OAJ08816.1 - 9.9e-16 57.2 3.4 1.4e-15 56.8 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger TIP41 PF04176.13 OAJ08817.1 - 2.3e-47 160.7 0.0 4e-45 153.4 0.0 3.2 2 1 0 2 2 2 2 TIP41-like family TSC21 PF15217.6 OAJ08818.1 - 0.097 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 TSC21 family IQ PF00612.27 OAJ08822.1 - 0.29 11.0 4.6 0.15 11.9 0.3 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif Ski2_N PF17911.1 OAJ08823.1 - 1.3e-41 141.6 0.0 2.2e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 OAJ08823.1 - 1e-08 35.2 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 OAJ08823.1 - 0.15 11.5 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein PMM PF03332.13 OAJ08827.1 - 4.3e-101 337.3 0.4 5.1e-101 337.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 OAJ08827.1 - 0.00012 22.0 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 OAJ08827.1 - 0.032 14.3 0.4 0.12 12.4 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function, DUF600 Response_reg PF00072.24 OAJ08828.1 - 1.2e-19 70.5 0.0 2.8e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ08828.1 - 8.8e-17 61.6 0.1 2e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 OAJ08828.1 - 2.6e-07 30.6 0.4 1.1e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PmbA_TldD PF01523.16 OAJ08828.1 - 0.17 11.7 8.2 0.029 14.2 1.3 2.4 2 0 0 2 2 2 0 Putative modulator of DNA gyrase Fmp27 PF10344.9 OAJ08833.1 - 0.11 10.6 1.4 0.21 9.7 1.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF5572 PF17733.1 OAJ08834.1 - 6e-18 64.4 0.5 1.2e-17 63.5 0.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DEC-1_N PF04625.13 OAJ08834.1 - 0.11 11.5 8.8 0.13 11.2 8.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Velvet PF11754.8 OAJ08835.1 - 2.5e-49 168.5 0.0 4.1e-49 167.8 0.0 1.3 1 1 0 1 1 1 1 Velvet factor WD40 PF00400.32 OAJ08836.1 - 6.5e-17 61.6 8.4 1.4e-07 32.1 0.2 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08836.1 - 9.4e-07 29.1 0.3 0.047 14.0 0.0 2.3 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ08836.1 - 0.0042 16.1 0.0 0.08 11.9 0.1 2.0 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ08836.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain Sorting_nexin PF03700.13 OAJ08840.1 - 0.038 14.5 3.9 0.05 14.2 3.6 1.3 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain Mito_carr PF00153.27 OAJ08841.1 - 0.068 13.1 0.4 4.4 7.3 0.1 3.2 3 0 0 3 3 3 0 Mitochondrial carrier protein Peptidase_C1_2 PF03051.15 OAJ08842.1 - 1.7e-32 112.8 0.0 1e-29 103.6 0.0 2.0 2 0 0 2 2 2 2 Peptidase C1-like family LPD34 PF18852.1 OAJ08845.1 - 0.0011 18.6 0.5 0.0019 17.8 0.5 1.3 1 0 0 1 1 1 1 Large polyvalent protein associated domain 34 Fib_alpha PF08702.10 OAJ08845.1 - 0.096 12.9 1.2 0.81 9.9 0.5 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GBR2_CC PF18455.1 OAJ08845.1 - 0.11 12.7 0.3 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain TMF_TATA_bd PF12325.8 OAJ08845.1 - 1.3 9.3 12.6 0.64 10.2 1.0 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CDC45 PF02724.14 OAJ08846.1 - 0.033 12.5 6.9 0.04 12.2 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ08846.1 - 2.7 6.0 14.0 4.1 5.4 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1640 PF07798.11 OAJ08850.1 - 1.7e-48 165.0 1.6 2.2e-48 164.6 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) F-box PF00646.33 OAJ08851.1 - 3.5e-06 26.7 0.0 9.3e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ08851.1 - 0.019 14.9 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 OAJ08852.1 - 0.00012 21.9 0.1 0.00025 20.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ08852.1 - 0.00031 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain APH PF01636.23 OAJ08856.1 - 8.7e-19 68.4 0.0 1.3e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PPR_3 PF13812.6 OAJ08857.1 - 0.13 12.4 0.0 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain NAD_binding_7 PF13241.6 OAJ08862.1 - 2.3e-27 95.4 0.0 3.9e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 OAJ08862.1 - 7.3e-25 86.4 0.6 1.2e-24 85.7 0.6 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 OAJ08862.1 - 6.8e-13 47.8 0.9 2e-12 46.3 0.2 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central SH3_1 PF00018.28 OAJ08863.1 - 1.8e-13 49.8 0.1 3.9e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ08863.1 - 2.7e-13 49.6 0.1 7e-13 48.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ08863.1 - 2.6e-12 46.2 0.2 8.5e-12 44.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 OAJ08863.1 - 4.2e-06 26.7 3.8 0.036 14.2 0.2 2.5 2 0 0 2 2 2 2 WW domain PQQ PF01011.21 OAJ08863.1 - 0.0015 18.3 0.0 0.0088 15.9 0.0 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat COesterase PF00135.28 OAJ08866.1 - 9e-95 318.5 0.1 1.9e-94 317.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ08866.1 - 2.4e-05 24.3 0.3 0.033 14.1 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Mtc PF03820.17 OAJ08867.1 - 1.4e-102 342.9 0.0 1.6e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pterin_4a PF01329.19 OAJ08872.1 - 0.057 13.6 0.2 0.12 12.6 0.1 1.6 1 1 1 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase PSK_trans_fac PF07704.11 OAJ08872.1 - 0.3 11.9 2.4 0.46 11.3 2.4 1.4 1 1 0 1 1 1 0 Rv0623-like transcription factor Acyltransferase PF01553.21 OAJ08881.1 - 1.8e-20 72.9 0.0 5e-20 71.5 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase ELL PF10390.9 OAJ08881.1 - 0.014 14.9 2.2 0.021 14.3 2.2 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL SR-25 PF10500.9 OAJ08881.1 - 0.46 10.1 7.8 0.82 9.2 7.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.16 OAJ08885.1 - 7e-39 133.7 40.8 7e-39 133.7 40.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ08885.1 - 8.8e-13 47.5 16.3 1.1e-12 47.2 16.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sporozoite_P67 PF05642.11 OAJ08886.1 - 0.042 12.0 1.4 0.048 11.8 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GATA PF00320.27 OAJ08889.1 - 8.2e-17 60.5 5.1 1.6e-16 59.6 5.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 OAJ08889.1 - 3.2e-13 49.3 0.9 5.9e-13 48.4 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FA_hydroxylase PF04116.13 OAJ08893.1 - 7.5e-13 49.0 5.7 9e-13 48.7 5.7 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ribonuclease_T2 PF00445.18 OAJ08894.1 - 1.8e-30 106.5 0.0 2.7e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Melibiase PF02065.18 OAJ08894.1 - 0.12 11.4 0.0 0.95 8.3 0.0 1.9 2 0 0 2 2 2 0 Melibiase DUF3292 PF11696.8 OAJ08898.1 - 5.7e-202 672.6 0.0 4.3e-122 408.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) DUF2722 PF10846.8 OAJ08899.1 - 0.0062 15.5 0.5 0.0062 15.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Med3 PF11593.8 OAJ08899.1 - 0.46 9.6 14.0 0.66 9.1 14.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GHMP_kinases_C PF08544.13 OAJ08899.1 - 5.5 7.4 9.3 1.8 9.0 0.1 2.6 2 1 1 3 3 3 0 GHMP kinases C terminal AMP-binding PF00501.28 OAJ08903.1 - 3.5e-67 226.8 0.2 4.4e-67 226.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ08903.1 - 2.7e-25 89.1 2.0 5.4e-25 88.2 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain EamA PF00892.20 OAJ08904.1 - 0.00021 21.5 25.7 0.0013 18.9 0.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 OAJ08904.1 - 1.6 8.0 7.8 3.1 7.1 2.8 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family MDM31_MDM32 PF08118.11 OAJ08909.1 - 1e-178 595.3 0.0 3.6e-178 593.5 0.0 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins SPX PF03105.19 OAJ08909.1 - 0.018 15.0 2.0 0.027 14.4 2.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 OAJ08909.1 - 1.8 7.3 5.5 2.8 6.7 5.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 OAJ08909.1 - 7.9 6.1 19.2 12 5.5 19.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 NOC3p PF07540.11 OAJ08915.1 - 1.1e-25 89.9 0.2 2.9e-24 85.3 0.0 2.9 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 OAJ08915.1 - 2.2e-12 47.3 0.0 2.2e-12 47.3 0.0 3.3 2 1 0 2 2 2 1 CBF/Mak21 family PHD PF00628.29 OAJ08918.1 - 0.0001 22.1 8.7 0.0001 22.1 8.7 2.7 2 1 0 2 2 2 1 PHD-finger FANCL_C PF11793.8 OAJ08918.1 - 0.06 13.5 1.1 0.18 12.0 1.1 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain C1_1 PF00130.22 OAJ08918.1 - 0.14 12.1 0.3 0.14 12.1 0.3 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 OAJ08918.1 - 0.34 11.2 8.2 0.037 14.3 2.5 2.4 2 1 0 2 2 2 0 PHD-like zinc-binding domain Zf_RING PF16744.5 OAJ08918.1 - 0.43 10.7 4.0 4.6 7.4 4.0 2.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 OAJ08918.1 - 6.7 6.4 8.8 0.45 10.1 0.7 3.1 3 0 0 3 3 3 0 PHD-finger ABC_membrane PF00664.23 OAJ08922.1 - 1.4e-06 28.2 0.0 1.5e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region SBDS PF01172.18 OAJ08923.1 - 1.9e-15 56.7 0.2 2.6e-15 56.3 0.2 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SpuA_C PF18033.1 OAJ08923.1 - 0.0071 16.4 0.1 0.01 15.9 0.1 1.3 1 1 0 1 1 1 1 SpuA C-terminal Methyltransf_25 PF13649.6 OAJ08924.1 - 0.00036 21.2 0.0 0.0012 19.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ08924.1 - 0.001 18.9 0.2 0.002 17.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ08924.1 - 0.0039 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAJ08924.1 - 0.0057 16.5 0.0 0.022 14.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ08924.1 - 0.17 12.6 0.0 0.48 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAJ08924.1 - 0.22 10.4 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ABA_GPCR PF12430.8 OAJ08925.1 - 3.6e-35 121.3 6.3 9.2e-35 120.0 6.3 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 OAJ08925.1 - 5.2e-14 52.1 0.9 1.2e-13 51.0 0.9 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal LcrR PF09621.10 OAJ08925.1 - 0.031 13.7 0.1 0.077 12.4 0.1 1.7 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Integrase_H2C2 PF17921.1 OAJ08928.1 - 8.2e-16 57.9 0.0 1.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ08928.1 - 3.3e-13 49.5 0.1 7.9e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ08928.1 - 1.5e-12 47.7 0.0 4.5e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ08928.1 - 4.5e-09 36.1 0.0 7.6e-07 28.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ08928.1 - 0.00057 20.5 1.2 0.0016 19.1 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ08928.1 - 0.01 16.1 0.1 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ08928.1 - 0.038 14.5 1.1 0.084 13.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ08928.1 - 0.054 13.8 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 OAJ08929.1 - 1.9e-11 44.1 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ08929.1 - 4e-05 23.6 0.0 7.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FAM219A PF15260.6 OAJ08929.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein family FAM219A FSA_C PF10479.9 OAJ08930.1 - 0.0036 15.5 0.6 0.0044 15.2 0.6 1.0 1 0 0 1 1 1 1 Fragile site-associated protein C-terminus DUF3275 PF11679.8 OAJ08930.1 - 1.8 8.5 3.8 2.4 8.1 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MAP65_ASE1 PF03999.12 OAJ08930.1 - 2 7.0 3.0 2.3 6.8 3.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) NAM-associated PF14303.6 OAJ08930.1 - 3.2 8.4 6.0 5.6 7.7 6.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pyr_redox_2 PF07992.14 OAJ08937.1 - 1.7e-35 122.7 0.0 5.4e-35 121.1 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ08937.1 - 1.9e-11 44.4 3.9 2.4e-09 37.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ08937.1 - 5.5e-05 22.7 0.2 7.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ08937.1 - 0.00012 21.4 0.1 0.027 13.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ08937.1 - 0.00042 19.6 0.0 0.0051 16.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ08937.1 - 0.0064 16.7 0.9 0.02 15.1 0.9 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ08937.1 - 0.0064 15.6 0.7 0.044 12.9 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 OAJ08937.1 - 0.023 13.4 1.2 1.7 7.3 0.9 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAJ08937.1 - 0.034 13.4 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 OAJ08937.1 - 0.47 10.3 1.7 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glutenin_hmw PF03157.13 OAJ08938.1 - 0.034 12.6 13.7 0.048 12.1 13.7 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit WD40 PF00400.32 OAJ08942.1 - 4.1e-13 49.6 0.6 1.2e-06 29.1 0.0 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ08942.1 - 0.049 13.9 0.0 3.7 7.9 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_1 PF00078.27 OAJ08945.1 - 8.7e-26 90.8 0.0 6.9e-25 87.9 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ08945.1 - 8.4e-14 51.4 0.0 2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08945.1 - 3.1e-11 43.2 0.0 6.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ08945.1 - 4.2e-10 39.9 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ08945.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase TAF4 PF05236.14 OAJ08949.1 - 0.4 10.4 2.1 0.68 9.6 2.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Phage_integrase PF00589.22 OAJ08951.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAJ08951.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) DNA_pol_viral_C PF00336.18 OAJ08952.1 - 0.0083 15.6 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain HNH_2 PF13391.6 OAJ08956.1 - 0.0077 16.3 0.1 0.012 15.8 0.1 1.4 1 1 0 1 1 1 1 HNH endonuclease FHA PF00498.26 OAJ08956.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 FHA domain BSP_II PF05432.11 OAJ08957.1 - 0.00072 19.4 9.9 0.00098 18.9 9.9 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 OAJ08957.1 - 0.01 14.1 13.8 0.011 14.1 13.8 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 OAJ08957.1 - 0.013 13.9 12.1 0.016 13.7 12.1 1.0 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 OAJ08957.1 - 0.02 14.4 14.8 0.023 14.1 14.8 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 OAJ08957.1 - 0.05 13.4 7.1 0.063 13.1 7.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RR_TM4-6 PF06459.12 OAJ08957.1 - 0.053 13.3 5.2 0.06 13.2 5.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 OAJ08957.1 - 0.1 12.8 2.4 0.12 12.6 2.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Roughex PF06020.11 OAJ08957.1 - 0.15 11.2 13.3 0.16 11.0 13.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SpoIIIAH PF12685.7 OAJ08957.1 - 0.17 11.7 6.3 0.18 11.6 6.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIF_alpha PF05793.12 OAJ08957.1 - 0.18 10.4 13.4 0.19 10.3 13.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 OAJ08957.1 - 0.25 10.6 15.1 0.28 10.5 15.1 1.1 1 0 0 1 1 1 0 BUD22 Tom22 PF04281.13 OAJ08957.1 - 0.6 9.9 5.9 0.84 9.4 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF4637 PF15470.6 OAJ08957.1 - 0.62 9.8 13.3 0.79 9.4 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NPR3 PF03666.13 OAJ08957.1 - 0.81 8.4 5.6 0.87 8.3 5.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 OAJ08957.1 - 1 8.7 19.2 1.2 8.4 19.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 OAJ08957.1 - 1.2 7.3 15.0 1.3 7.2 15.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.8 OAJ08957.1 - 1.6 7.6 6.5 1.8 7.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Herpes_LMP1 PF05297.11 OAJ08957.1 - 1.9 7.6 3.9 2 7.5 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DNA_pol_phi PF04931.13 OAJ08957.1 - 1.9 6.5 23.5 2.1 6.3 23.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 OAJ08957.1 - 2.9 6.8 4.0 3 6.7 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 OAJ08957.1 - 3.2 5.4 5.8 3.7 5.2 5.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 OAJ08957.1 - 4.2 6.0 6.3 4.6 5.9 6.3 1.0 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 OAJ08957.1 - 4.5 6.5 18.1 6.1 6.1 18.1 1.2 1 0 0 1 1 1 0 NOA36 protein Merozoite_SPAM PF07133.11 OAJ08957.1 - 4.8 7.1 23.2 5.9 6.9 23.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 OAJ08957.1 - 5.7 5.6 5.5 5.9 5.6 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PPP4R2 PF09184.11 OAJ08957.1 - 7.6 6.0 15.5 9.2 5.8 15.5 1.1 1 0 0 1 1 1 0 PPP4R2 V_ATPase_I PF01496.19 OAJ08957.1 - 8.8 4.1 4.6 9.6 4.0 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIN_4 PF13638.6 OAJ08958.1 - 0.0036 17.6 0.0 0.0036 17.6 0.0 1.1 1 0 0 1 1 1 1 PIN domain RT_RNaseH_2 PF17919.1 OAJ08962.1 - 2.8e-19 69.0 0.0 1.4e-12 47.5 0.0 2.8 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ08962.1 - 1.7e-15 56.9 0.0 3.7e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ08962.1 - 3.3e-14 53.0 0.0 5.4e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08962.1 - 7.2e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ08962.1 - 2.5e-09 37.3 0.0 0.0012 19.1 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase MSA-2c PF12238.8 OAJ08963.1 - 4.5 7.2 7.2 6.6 6.7 7.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3546 PF12066.8 OAJ08968.1 - 6e-17 61.8 2.0 7e-17 61.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 OAJ08968.1 - 2.5e-07 31.3 0.0 2.5e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 Arsenite-resistance protein 2 RVT_3 PF13456.6 OAJ08971.1 - 0.066 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ08971.1 - 0.19 11.1 0.1 0.5 9.7 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain GRP PF07172.11 OAJ08971.1 - 5.4 7.8 19.2 11 6.7 19.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.22 OAJ08974.1 - 1.7e-09 37.4 0.0 0.00011 22.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec5 PF15469.6 OAJ08975.1 - 5.2e-55 186.2 2.9 1.1e-54 185.1 0.0 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 OAJ08975.1 - 0.011 15.7 0.4 0.071 13.2 0.0 2.6 2 0 0 2 2 2 0 Vps51/Vps67 RINT1_TIP1 PF04437.13 OAJ08975.1 - 0.49 9.2 7.1 0.069 12.0 0.2 2.9 3 2 1 4 4 4 0 RINT-1 / TIP-1 family CENP-H PF05837.12 OAJ08975.1 - 1.3 9.5 0.0 1.3 9.5 0.0 3.2 3 1 0 3 3 3 0 Centromere protein H (CENP-H) Lyase_1 PF00206.20 OAJ08978.1 - 8.7e-118 393.3 0.0 1.3e-117 392.7 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 OAJ08978.1 - 2.2e-19 69.6 0.0 6.7e-19 68.1 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus GLTSCR1 PF15249.6 OAJ08979.1 - 2.1e-10 41.0 0.0 4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein NAD_binding_10 PF13460.6 OAJ08985.1 - 6.4e-25 88.1 0.0 8.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ08985.1 - 0.00023 20.7 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAJ08985.1 - 0.0033 17.0 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Phage_tail_APC PF16778.5 OAJ08985.1 - 0.0038 17.1 0.3 3 7.8 0.2 2.8 3 1 0 3 3 3 2 Phage tail assembly chaperone protein NAD_binding_4 PF07993.12 OAJ08985.1 - 0.18 10.9 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein TAP42 PF04177.12 OAJ08986.1 - 9.8e-66 222.1 0.0 1.4e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 TAP42-like family SUIM_assoc PF16619.5 OAJ08986.1 - 0.026 14.6 3.9 1.8 8.7 0.0 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CDT1_C PF16679.5 OAJ08986.1 - 0.6 10.6 0.1 0.6 10.6 0.1 2.4 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain CAP_N PF01213.19 OAJ08986.1 - 1.7 8.1 11.1 0.018 14.6 2.7 1.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal TFIIA PF03153.13 OAJ08986.1 - 7.1 6.5 10.9 1.2e+02 2.4 10.9 2.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH_2 PF17919.1 OAJ08995.1 - 3.5e-32 110.4 0.0 1.1e-31 108.9 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ08995.1 - 6.9e-30 103.4 0.0 2e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ08995.1 - 2e-18 66.7 0.0 4.3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ08995.1 - 5e-17 62.2 0.2 1.4e-16 60.7 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ08995.1 - 1.1e-13 51.1 0.0 3.2e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ08995.1 - 0.0054 16.5 0.0 0.015 15.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 OAJ08995.1 - 0.27 11.4 1.7 0.63 10.2 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle OPT PF03169.15 OAJ08998.1 - 1.6e-154 515.9 51.8 1.9e-154 515.7 51.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MFS_1 PF07690.16 OAJ09008.1 - 1.3e-40 139.4 27.4 1e-36 126.6 9.1 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ09008.1 - 4e-09 35.9 1.4 4e-09 35.9 1.4 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter UPF0242 PF06785.11 OAJ09008.1 - 0.049 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COX2-transmemb PF09125.10 OAJ09008.1 - 0.39 10.5 0.0 0.39 10.5 0.0 2.4 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane OATP PF03137.20 OAJ09008.1 - 0.61 8.3 12.4 0.021 13.2 2.3 3.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Phage_integrase PF00589.22 OAJ09014.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family RVT_1 PF00078.27 OAJ09015.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.7 OAJ09019.1 - 0.00015 21.5 0.6 0.00033 20.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ09019.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain UBA2_C PF16195.5 OAJ09019.1 - 1.5 9.6 8.1 4.3 8.1 5.5 2.3 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Serine_protease PF18405.1 OAJ09021.1 - 0.055 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease TFIID-31kDa PF02291.15 OAJ09029.1 - 1.7e-45 154.0 0.0 2.3e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 OAJ09029.1 - 0.0036 17.3 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated MAD PF05557.13 OAJ09030.1 - 1.6e-42 145.8 57.7 9e-35 120.2 9.7 2.3 2 1 0 2 2 2 2 Mitotic checkpoint protein HALZ PF02183.18 OAJ09030.1 - 1.4e-05 25.2 26.9 0.065 13.5 3.1 6.5 5 1 1 6 6 6 3 Homeobox associated leucine zipper SKA2 PF16740.5 OAJ09030.1 - 0.00018 21.3 3.3 0.00018 21.3 3.3 5.7 6 1 1 7 7 7 2 Spindle and kinetochore-associated protein 2 COG5 PF10392.9 OAJ09030.1 - 0.0047 17.1 5.1 0.0047 17.1 5.1 3.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 DUF5101 PF17031.5 OAJ09030.1 - 0.18 11.9 8.0 1.3 9.2 0.4 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF5101) KIAA1430 PF13879.6 OAJ09030.1 - 0.4 11.4 0.0 0.4 11.4 0.0 3.6 4 2 0 4 4 4 0 KIAA1430 homologue KIP1 PF07765.12 OAJ09030.1 - 0.62 10.2 8.1 0.17 12.1 2.5 3.1 3 0 0 3 3 3 0 KIP1-like protein DUF4407 PF14362.6 OAJ09030.1 - 9.7 5.4 62.1 0.059 12.7 2.6 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) DLH PF01738.18 OAJ09035.1 - 1.3e-18 67.4 0.0 1.5e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family SOR_SNZ PF01680.17 OAJ09036.1 - 1.9e-112 374.1 5.7 2.6e-112 373.6 5.7 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 OAJ09036.1 - 8e-07 28.6 8.3 2.7e-05 23.6 0.8 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 OAJ09036.1 - 0.00045 19.4 0.5 0.63 9.1 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 OAJ09036.1 - 0.0073 16.3 0.2 0.034 14.2 0.0 2.1 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 OAJ09036.1 - 0.055 12.8 6.4 0.56 9.5 0.4 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase DUF393 PF04134.12 OAJ09040.1 - 0.14 13.5 0.8 0.42 11.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF393 ADIP PF11559.8 OAJ09040.1 - 0.31 11.1 7.8 0.15 12.1 5.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding CHDCT2 PF08074.11 OAJ09040.1 - 0.34 11.1 5.0 1.1 9.4 4.8 1.6 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain V-ATPase_G_2 PF16999.5 OAJ09040.1 - 0.79 10.2 14.2 1.8 9.0 14.2 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HNF-1_N PF04814.13 OAJ09045.1 - 1.5 9.4 10.1 0.77 10.3 1.0 2.6 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus WD40 PF00400.32 OAJ09046.1 - 9.1e-12 45.3 5.2 0.00069 20.4 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09046.1 - 0.00076 19.7 0.0 1 9.7 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SAPS PF04499.15 OAJ09053.1 - 0.0011 17.8 6.3 0.0015 17.4 6.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein BUD22 PF09073.10 OAJ09053.1 - 0.0022 17.4 18.3 0.0022 17.4 18.3 2.1 3 0 0 3 3 3 1 BUD22 DUF2151 PF10221.9 OAJ09053.1 - 0.2 10.2 5.4 0.28 9.8 5.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DDHD PF02862.17 OAJ09053.1 - 0.58 10.3 6.3 0.057 13.6 1.4 1.8 2 0 0 2 2 2 0 DDHD domain Nop14 PF04147.12 OAJ09053.1 - 0.77 7.9 28.2 1 7.5 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4407 PF14362.6 OAJ09053.1 - 0.85 8.9 13.4 1.5 8.1 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 OAJ09053.1 - 2 8.1 17.8 3.4 7.4 17.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 OAJ09053.1 - 2.6 6.2 22.0 4.1 5.6 22.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 OAJ09053.1 - 3.3 6.6 25.1 5.1 6.0 25.1 1.3 1 0 0 1 1 1 0 Paf1 PPP4R2 PF09184.11 OAJ09053.1 - 3.4 7.2 22.8 6.5 6.3 22.8 1.4 1 0 0 1 1 1 0 PPP4R2 Tim54 PF11711.8 OAJ09053.1 - 6.8 5.4 13.4 12 4.5 13.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Fe_hyd_lg_C PF02906.14 OAJ09054.1 - 1.4e-53 182.1 0.0 3.6e-53 180.7 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain RVT_2 PF07727.14 OAJ09063.1 - 1.3e-73 247.6 0.0 2.2e-73 246.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09063.1 - 2.2e-22 79.5 0.0 6.4e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09063.1 - 3.9e-06 26.6 0.0 8.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09063.1 - 1.8e-05 24.4 0.1 5.5e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ09064.1 - 3.4e-05 23.5 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ09064.1 - 0.067 13.3 4.1 0.11 12.6 4.1 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09064.1 - 0.67 9.8 4.0 1.1 9.2 4.0 1.3 1 0 0 1 1 1 0 Zinc knuckle SKG6 PF08693.10 OAJ09068.1 - 6.1 6.3 7.2 14 5.2 7.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain eIF-3_zeta PF05091.12 OAJ09073.1 - 6.5e-10 38.6 0.0 7.4e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BCAS2 PF05700.11 OAJ09074.1 - 9.6e-40 136.5 4.2 1.1e-39 136.3 4.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CASP_C PF08172.12 OAJ09074.1 - 0.00024 20.5 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 CASP C terminal T2SSE_N PF05157.15 OAJ09074.1 - 0.0082 16.4 0.2 0.12 12.7 0.1 2.5 1 1 2 3 3 3 1 Type II secretion system (T2SS), protein E, N-terminal domain HtaA PF04213.13 OAJ09074.1 - 0.1 13.1 0.2 0.16 12.4 0.2 1.3 1 0 0 1 1 1 0 Htaa Glyco_hydro_47 PF01532.20 OAJ09082.1 - 2.2e-84 284.0 0.0 2.7e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 OAJ09082.1 - 0.12 11.9 0.2 29 4.0 0.2 2.9 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Tfb4 PF03850.14 OAJ09083.1 - 6.1e-34 117.8 14.2 2e-19 70.1 8.1 4.0 2 1 1 3 3 3 3 Transcription factor Tfb4 Chorion_2 PF03964.15 OAJ09083.1 - 6.5 7.6 11.1 41 5.1 6.0 2.4 2 0 0 2 2 2 0 Chorion family 2 Prenyltrans PF00432.21 OAJ09089.1 - 0.046 13.5 0.2 0.094 12.5 0.2 1.4 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF3979 PF13141.6 OAJ09089.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Stm1_N PF09598.10 OAJ09089.1 - 0.67 10.8 8.0 1.7 9.6 8.0 1.7 1 0 0 1 1 1 0 Stm1 Phage_int_SAM_1 PF02899.17 OAJ09090.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 OAJ09090.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family IucA_IucC PF04183.12 OAJ09091.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 IucA / IucC family Na_H_Exchanger PF00999.21 OAJ09094.1 - 1.3e-56 192.0 49.3 2e-56 191.4 49.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DnaJ_CXXCXGXG PF00684.19 OAJ09099.1 - 0.00018 21.8 4.8 0.028 14.8 0.3 2.3 2 0 0 2 2 2 2 DnaJ central domain tRNA_int_endo PF01974.17 OAJ09100.1 - 3.1e-18 65.6 0.1 6.2e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 OAJ09100.1 - 0.0025 17.5 0.7 0.0057 16.3 0.7 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain PQ-loop PF04193.14 OAJ09101.1 - 4.3e-29 100.1 9.2 1.2e-17 63.4 2.2 2.4 2 0 0 2 2 2 2 PQ loop repeat Frag1 PF10277.9 OAJ09101.1 - 0.00093 18.8 6.0 0.0014 18.2 6.0 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2781 PF10914.8 OAJ09101.1 - 0.002 18.6 1.3 0.0032 17.9 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Arteri_Gl PF00951.18 OAJ09101.1 - 0.013 15.3 0.5 0.026 14.4 0.5 1.4 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Mg_trans_NIPA PF05653.14 OAJ09101.1 - 0.017 14.3 3.0 0.038 13.1 2.3 1.7 1 1 1 2 2 2 0 Magnesium transporter NIPA MARVEL PF01284.23 OAJ09101.1 - 0.026 14.6 0.8 0.026 14.6 0.8 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF2975 PF11188.8 OAJ09101.1 - 0.19 11.6 6.1 1.9 8.4 2.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1218 PF06749.12 OAJ09101.1 - 0.54 10.8 5.4 0.15 12.6 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Pyr_redox_2 PF07992.14 OAJ09107.1 - 3.9e-37 128.1 0.7 5.9e-37 127.5 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ09107.1 - 1.7e-18 66.6 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ09107.1 - 2.7e-15 56.7 2.3 8.3e-14 51.9 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ09107.1 - 6.5e-15 54.9 0.0 6e-14 51.8 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 OAJ09107.1 - 8.3e-13 48.5 6.0 5.5e-10 39.4 6.2 2.6 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 OAJ09107.1 - 8.5e-12 44.9 0.1 4.8e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 OAJ09107.1 - 6.2e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 OAJ09107.1 - 8.3e-06 25.6 0.0 0.0099 15.8 0.1 2.9 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 OAJ09107.1 - 0.00014 21.9 3.2 0.31 11.0 0.1 3.4 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 OAJ09107.1 - 0.0027 16.8 0.7 1.4 7.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ09107.1 - 0.0085 15.7 5.6 0.067 12.8 0.2 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ09107.1 - 0.015 15.5 0.4 0.053 13.8 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 OAJ09107.1 - 0.038 14.2 3.0 2.7 8.3 0.1 3.3 3 0 0 3 3 3 0 TrkA-N domain GIDA PF01134.22 OAJ09107.1 - 0.12 11.4 0.2 5.8 5.9 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAJ09107.1 - 0.19 11.0 0.7 18 4.4 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_15 PF00723.21 OAJ09113.1 - 1.4e-79 268.0 0.1 1.9e-79 267.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 NAC PF01849.18 OAJ09114.1 - 3.6e-21 74.9 0.0 6.1e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 NAC domain TMEM154 PF15102.6 OAJ09118.1 - 0.17 11.8 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family Ofd1_CTDD PF10637.9 OAJ09118.1 - 0.23 10.8 1.2 0.54 9.5 1.2 1.6 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Spt20 PF12090.8 OAJ09118.1 - 0.54 9.8 25.7 0.77 9.3 6.3 3.0 3 0 0 3 3 3 0 Spt20 family SUIM_assoc PF16619.5 OAJ09118.1 - 9.3 6.4 30.7 0.33 11.0 5.9 5.0 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 OAJ09119.1 - 4.3 8.2 13.9 1.3 9.9 8.7 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FA_desaturase PF00487.24 OAJ09122.1 - 1.7e-11 44.5 8.0 2.3e-11 44.1 8.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3425 PF11905.8 OAJ09124.1 - 1.2e-10 41.4 0.4 3.6e-10 39.9 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAJ09124.1 - 2e-07 31.0 4.6 2e-07 31.0 4.6 2.1 2 1 0 2 2 2 1 bZIP transcription factor UCR_14kD PF02271.16 OAJ09124.1 - 0.085 12.8 0.5 0.19 11.7 0.5 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit bZIP_2 PF07716.15 OAJ09124.1 - 0.29 11.2 8.5 0.49 10.5 4.7 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Cytomega_UL20A PF05984.12 OAJ09127.1 - 0.21 11.9 5.4 0.17 12.2 3.1 2.0 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein Peptidase_C50 PF03568.17 OAJ09128.1 - 6.3e-108 361.4 0.0 8e-108 361.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 Ribosomal_L6 PF00347.23 OAJ09129.1 - 8.1e-18 64.9 0.0 1.1e-10 42.1 0.0 3.7 4 0 0 4 4 4 3 Ribosomal protein L6 WD40 PF00400.32 OAJ09138.1 - 1.5e-18 66.8 3.3 0.00041 21.1 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09138.1 - 0.00023 21.4 0.0 10 6.5 0.0 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 OAJ09138.1 - 4.4 7.2 34.8 1.9 8.4 10.4 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Fmp27 PF10344.9 OAJ09138.1 - 9.2 4.2 7.1 20 3.1 7.1 1.5 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Peptidase_S8 PF00082.22 OAJ09142.1 - 2.2e-39 135.5 0.0 9.1e-39 133.5 0.0 2.2 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ09142.1 - 5.8e-10 39.9 0.2 2.1e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 Fn3-like domain ChiW_Ig_like PF18683.1 OAJ09142.1 - 0.65 10.2 4.3 9.3 6.5 0.2 4.1 4 0 0 4 4 4 0 Chitinase W immunoglobulin-like domain Pkinase PF00069.25 OAJ09146.1 - 6.2e-43 147.1 0.0 9.1e-41 140.0 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09146.1 - 6.7e-26 91.1 0.0 1.8e-25 89.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ09146.1 - 0.00047 20.2 0.0 0.00047 20.2 0.0 3.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ09146.1 - 0.6 8.8 5.0 0.84 8.3 0.0 2.3 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 OAJ09146.1 - 1.7 8.6 39.4 0.013 15.5 30.4 2.0 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF1682 PF07946.14 OAJ09146.1 - 5.4 6.1 10.9 8.6 5.5 10.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) XRN_M PF17846.1 OAJ09146.1 - 7.5 5.4 10.0 12 4.7 10.0 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF1282 PF06930.12 OAJ09151.1 - 0.09 12.6 5.9 0.16 11.8 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) 7tm_7 PF08395.12 OAJ09151.1 - 0.1 11.8 0.7 0.14 11.3 0.7 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Ni_hydr_CYTB PF01292.20 OAJ09151.1 - 0.13 11.8 5.1 0.19 11.3 4.6 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4293 PF14126.6 OAJ09151.1 - 0.31 11.3 3.7 0.11 12.7 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Stevor PF17410.2 OAJ09151.1 - 7.1 6.1 4.7 0.87 9.1 0.3 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame Pantoate_ligase PF02569.15 OAJ09160.1 - 2.4e-88 295.8 0.0 5.7e-88 294.6 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase BPL_N PF09825.9 OAJ09165.1 - 3.4e-95 319.3 0.0 4.2e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 OAJ09165.1 - 2.6e-17 63.0 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 OAJ09165.1 - 0.15 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AMP-binding PF00501.28 OAJ09172.1 - 1.2e-82 277.8 0.0 1.4e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ09172.1 - 8.9e-14 52.2 0.5 1.8e-13 51.3 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cwf21 PF08312.12 OAJ09174.1 - 1.7e-15 56.8 5.3 1.7e-15 56.8 5.3 2.6 2 1 0 2 2 2 1 cwf21 domain GMC_oxred_N PF00732.19 OAJ09179.1 - 2e-60 204.7 0.0 2.7e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ09179.1 - 2.7e-27 96.1 0.0 5.3e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ09179.1 - 1.1e-06 28.8 0.0 1.1e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ09179.1 - 1.4e-05 24.3 0.0 0.00013 21.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAJ09179.1 - 1.6e-05 24.7 0.3 4.8e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ09179.1 - 3.3e-05 23.1 0.0 6.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAJ09179.1 - 5.6e-05 22.5 0.1 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ09179.1 - 0.0071 15.6 0.1 0.019 14.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ09179.1 - 0.069 11.8 0.6 0.19 10.4 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 OAJ09179.1 - 0.077 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Alpha_GJ PF03229.13 OAJ09179.1 - 8.2 7.0 16.3 7.1 7.2 3.3 2.6 2 0 0 2 2 2 0 Alphavirus glycoprotein J Pal1 PF08316.11 OAJ09185.1 - 2.1e-15 57.7 0.6 4.5e-15 56.6 0.6 1.6 1 1 0 1 1 1 1 Pal1 cell morphology protein PPP4R2 PF09184.11 OAJ09186.1 - 3.4e-11 43.3 0.0 3.4e-11 43.3 0.0 2.7 2 1 0 2 2 2 1 PPP4R2 ANAPC_CDC26 PF10471.9 OAJ09186.1 - 0.0049 17.7 4.0 0.0049 17.7 4.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 Rad21_Rec8_N PF04825.13 OAJ09194.1 - 0.073 13.3 0.1 0.27 11.4 0.1 1.9 1 1 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein RT_RNaseH PF17917.1 OAJ09204.1 - 2.8e-35 120.8 0.0 6.2e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09204.1 - 2e-31 108.0 0.0 6e-31 106.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09204.1 - 2.7e-30 105.5 0.2 4.1e-30 105.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09204.1 - 1.6e-22 79.4 0.0 4.3e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ09204.1 - 2.1e-15 56.3 0.1 4.6e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 OAJ09204.1 - 1.8e-12 47.5 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ09204.1 - 8.3e-08 32.3 0.0 3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 H2C2 zinc finger DUF1796 PF08795.10 OAJ09204.1 - 0.039 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) Exo_endo_phos PF03372.23 OAJ09206.1 - 0.073 12.6 3.5 0.2 11.1 3.5 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 OAJ09206.1 - 0.13 12.1 0.1 0.5 10.2 0.0 2.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase ISG65-75 PF11727.8 OAJ09214.1 - 0.13 11.5 0.2 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein ENT PF03735.14 OAJ09216.1 - 0.046 13.8 2.5 2.1 8.5 0.2 2.2 1 1 1 2 2 2 0 ENT domain DUF1296 PF06972.11 OAJ09216.1 - 0.065 13.4 0.5 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) 4HBT PF03061.22 OAJ09217.1 - 3.8e-05 24.0 0.4 0.064 13.6 0.0 3.1 3 1 0 3 3 3 2 Thioesterase superfamily SR-25 PF10500.9 OAJ09217.1 - 3 7.4 12.9 6.8 6.2 12.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Syntaxin-18_N PF10496.9 OAJ09225.1 - 2.7e-07 30.7 0.1 2.7e-07 30.7 0.1 3.0 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 OAJ09225.1 - 0.028 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 SNARE domain Abhydrolase_3 PF07859.13 OAJ09226.1 - 2.3e-25 89.7 0.0 4.1e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ09226.1 - 1.6e-07 31.0 0.1 0.0016 18.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ09226.1 - 0.00031 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ribosomal_60s PF00428.19 OAJ09226.1 - 0.027 15.1 15.8 0.044 14.4 11.4 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_22 PF03901.17 OAJ09227.1 - 4.8e-27 95.2 9.1 6e-27 94.9 9.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Peptidase_M18 PF02127.15 OAJ09230.1 - 1.6e-158 528.1 0.0 2.1e-158 527.7 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 OAJ09230.1 - 0.00019 20.6 0.0 0.03 13.3 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Exo_endo_phos PF03372.23 OAJ09231.1 - 4.2e-16 59.2 0.6 6.9e-16 58.5 0.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 OAJ09243.1 - 4.9e-22 77.5 0.0 7.3e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ09243.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif HsbA PF12296.8 OAJ09244.1 - 1.3e-16 61.1 15.7 1.3e-16 61.1 15.7 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A RVT_N PF13655.6 OAJ09244.1 - 0.074 13.3 2.1 9.3 6.6 0.2 2.3 1 1 1 2 2 2 0 N-terminal domain of reverse transcriptase Nucleopor_Nup85 PF07575.13 OAJ09247.1 - 0.17 10.4 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Vfa1 PF08432.10 OAJ09247.1 - 1.3 9.3 10.3 8 6.7 0.7 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Med14 PF08638.11 OAJ09253.1 - 2.3e-44 151.1 0.0 4.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 TAtT PF16811.5 OAJ09253.1 - 0.099 11.9 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 TRAP transporter T-component Collagen PF01391.18 OAJ09258.1 - 0.00048 19.8 2.6 0.00067 19.4 2.6 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) HsbA PF12296.8 OAJ09259.1 - 1.4e-17 64.3 6.5 1.4e-17 64.3 6.5 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A TIP49 PF06068.13 OAJ09265.1 - 3.4e-156 519.8 0.0 5.4e-156 519.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ09265.1 - 2.8e-21 75.4 0.1 7.7e-21 74.0 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ09265.1 - 2.2e-10 41.1 0.1 4.1e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ09265.1 - 5.5e-09 36.0 0.1 1.7e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ09265.1 - 1.5e-07 31.8 0.1 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ09265.1 - 5.3e-05 23.2 0.2 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 OAJ09265.1 - 0.00017 22.0 0.5 0.068 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ09265.1 - 0.00029 21.3 0.1 0.0025 18.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 OAJ09265.1 - 0.00038 20.7 0.1 0.00073 19.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ09265.1 - 0.0038 16.6 0.1 0.29 10.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ09265.1 - 0.0099 16.1 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ09265.1 - 0.011 15.3 0.3 0.011 15.3 0.3 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OAJ09265.1 - 0.018 14.7 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ09265.1 - 0.019 14.9 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 OAJ09265.1 - 0.028 14.2 0.1 0.092 12.5 0.1 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 OAJ09265.1 - 0.04 13.4 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 OAJ09265.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 OAJ09265.1 - 0.073 12.8 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 OAJ09265.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DDE_3 PF13358.6 OAJ09266.1 - 2.8e-16 59.6 0.0 5.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ09266.1 - 0.0017 18.9 0.0 0.0056 17.3 0.0 1.9 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ09266.1 - 0.0085 15.7 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_29 PF13551.6 OAJ09266.1 - 0.0097 15.9 1.6 0.27 11.3 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn helix Arteri_nucleo PF01481.16 OAJ09266.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein STIMATE PF12400.8 OAJ09273.1 - 2.3e-39 134.8 6.1 3.3e-39 134.3 6.1 1.2 1 0 0 1 1 1 1 STIMATE family RAP1 PF07218.11 OAJ09277.1 - 1.3 7.2 8.1 2.5 6.3 8.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SEEEED PF14797.6 OAJ09277.1 - 1.3 9.2 36.9 0.03 14.5 21.6 3.3 3 0 0 3 3 3 0 Serine-rich region of AP3B1, clathrin-adaptor complex Phage_integrase PF00589.22 OAJ09278.1 - 2.5e-06 27.4 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF900 PF05990.12 OAJ09278.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2716 PF10898.8 OAJ09279.1 - 0.024 15.0 0.3 0.034 14.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) mono-CXXC PF15626.6 OAJ09279.1 - 0.065 13.6 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 single CXXC unit Phage_int_SAM_4 PF13495.6 OAJ09279.1 - 0.094 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ribosomal_L23 PF00276.20 OAJ09284.1 - 5.4e-07 29.9 0.0 3.8e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 ANAPC4_WD40 PF12894.7 OAJ09285.1 - 0.0064 16.8 0.0 1.5 9.1 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ09285.1 - 0.042 14.7 2.0 46 5.1 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Sec1 PF00995.23 OAJ09286.1 - 4.9e-05 22.8 0.0 5.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DTC PF18102.1 OAJ09286.1 - 0.031 14.4 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Deltex C-terminal domain TPR_12 PF13424.6 OAJ09293.1 - 0.012 15.9 0.7 0.037 14.3 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1465 PF07323.12 OAJ09294.1 - 0.027 14.3 4.0 0.39 10.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Laminin_II PF06009.12 OAJ09294.1 - 0.027 14.5 1.7 0.038 14.0 0.3 1.8 1 1 1 2 2 2 0 Laminin Domain II TBCA PF02970.16 OAJ09294.1 - 0.027 14.8 0.6 0.04 14.3 0.6 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A Jnk-SapK_ap_N PF09744.9 OAJ09294.1 - 0.056 13.7 1.7 0.14 12.3 1.8 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_CLD PF14073.6 OAJ09294.1 - 0.057 13.4 1.7 0.069 13.2 1.7 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 Seryl_tRNA_N PF02403.22 OAJ09294.1 - 0.1 12.8 3.1 0.27 11.5 3.0 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TssO PF17561.2 OAJ09294.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 Type VI secretion system, TssO GreA_GreB_N PF03449.15 OAJ09294.1 - 0.16 12.2 2.7 0.3 11.3 2.4 1.7 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal DnaJ-X PF14308.6 OAJ09301.1 - 1.1e-48 165.5 1.0 2.7e-48 164.2 1.0 1.6 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ09301.1 - 7.6e-25 86.8 0.3 7.6e-25 86.8 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Tmemb_55A PF09788.9 OAJ09301.1 - 0.13 11.4 0.8 0.23 10.5 0.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 55A HA2 PF04408.23 OAJ09301.1 - 4.1 7.7 7.7 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Helicase associated domain (HA2) NOG1_N PF17835.1 OAJ09301.1 - 7 6.6 8.2 2.2 8.2 1.2 2.7 2 0 0 2 2 2 0 NOG1 N-terminal helical domain LRR_4 PF12799.7 OAJ09302.1 - 0.0044 17.4 0.5 0.12 12.8 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) SGT1 PF07093.11 OAJ09305.1 - 3.3e-26 91.9 0.0 3.3e-26 91.9 0.0 4.6 4 1 1 5 5 5 2 SGT1 protein Flavin_Reduct PF01613.18 OAJ09306.1 - 4.3e-32 111.3 0.5 6.3e-32 110.8 0.5 1.2 1 0 0 1 1 1 1 Flavin reductase like domain ADK PF00406.22 OAJ09307.1 - 4.9e-43 146.8 0.0 6.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ09307.1 - 1.9e-22 80.1 0.0 5.6e-22 78.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ09307.1 - 7.8e-14 51.4 0.0 1.7e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAJ09307.1 - 0.016 15.8 0.0 0.027 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ09307.1 - 0.023 14.8 0.0 0.055 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Asp PF00026.23 OAJ09313.1 - 1e-45 156.6 0.0 2.7e-45 155.1 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ09313.1 - 2e-08 34.7 0.2 0.00076 19.8 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal SHR3_chaperone PF08229.11 OAJ09314.1 - 1.5e-39 134.9 0.0 2e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 Tlr3_TMD PF17968.1 OAJ09314.1 - 2.1 8.6 5.0 7 6.9 0.3 2.9 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Ras PF00071.22 OAJ09315.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ09315.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF863 PF05904.11 OAJ09316.1 - 0.75 8.2 7.0 0.8 8.1 7.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) FAM199X PF15814.5 OAJ09316.1 - 5.1 6.1 14.9 6.5 5.7 14.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X F-box-like PF12937.7 OAJ09321.1 - 0.041 13.8 0.5 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 F-box-like DUF596 PF04591.12 OAJ09322.1 - 0.011 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Mitoc_L55 PF09776.9 OAJ09329.1 - 0.47 10.2 1.9 0.71 9.6 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 RNA_pol_Rpb1_1 PF04997.12 OAJ09339.1 - 5.7e-92 308.4 0.0 6.5e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAJ09339.1 - 3.6e-13 50.1 0.0 5.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RrnaAD PF00398.20 OAJ09340.1 - 1.9e-11 43.5 0.0 4.7e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCI PF01399.27 OAJ09341.1 - 1.8e-20 73.4 0.0 4.6e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN5_C PF18098.1 OAJ09341.1 - 1.7e-11 44.0 0.1 5e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5588 PF17826.1 OAJ09341.1 - 0.00037 19.5 0.2 0.00054 18.9 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5588) TonB_N PF16031.5 OAJ09341.1 - 0.0029 18.1 6.3 0.0049 17.4 6.3 1.3 1 0 0 1 1 1 1 TonB polyproline region TPR_14 PF13428.6 OAJ09341.1 - 0.14 13.1 4.2 10 7.3 2.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ09341.1 - 0.24 11.7 2.7 1.8 9.0 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ09341.1 - 0.56 11.0 3.6 18 6.4 2.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ09341.1 - 0.59 10.7 5.0 6.4 7.4 1.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Hus1 PF04005.12 OAJ09347.1 - 7e-71 238.7 0.1 8.6e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 Hus1-like protein DUF1681 PF07933.14 OAJ09348.1 - 4.3e-50 169.3 0.0 5e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Pga1 PF10333.9 OAJ09353.1 - 0.066 13.1 0.6 11 5.8 0.3 2.6 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator Ysc84 PF04366.12 OAJ09358.1 - 2.7e-42 143.5 1.7 6.7e-41 139.0 0.2 2.1 2 0 0 2 2 2 2 Las17-binding protein actin regulator AhpC-TSA PF00578.21 OAJ09363.1 - 3.3e-20 72.2 0.0 5.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ09363.1 - 1.3e-12 47.6 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin FIST PF08495.10 OAJ09364.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 FIST N domain RT_RNaseH PF17917.1 OAJ09367.1 - 1.7e-28 99.0 0.0 4.3e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09367.1 - 6.8e-19 67.8 0.0 1.4e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09367.1 - 5.8e-17 61.6 0.0 2e-16 59.8 0.0 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ09367.1 - 3e-15 56.4 0.5 5.6e-15 55.5 0.5 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09367.1 - 2.9e-11 43.6 0.0 9.2e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 OAJ09367.1 - 2.4e-08 33.8 0.0 4.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ09367.1 - 1.1e-05 25.9 0.0 2.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ09367.1 - 3.6e-05 24.3 0.0 7.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 OAJ09367.1 - 0.00028 20.8 2.6 0.00028 20.8 2.6 1.9 2 0 0 2 2 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ09367.1 - 0.00071 19.8 0.2 0.0031 17.8 0.1 2.3 2 0 0 2 2 1 1 Retrotransposon gag protein Chromo PF00385.24 OAJ09367.1 - 0.0069 16.3 0.2 0.022 14.7 0.2 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 OAJ09367.1 - 0.015 15.5 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 1 0 H2C2 zinc finger zf-CCHC_2 PF13696.6 OAJ09367.1 - 0.064 13.1 2.6 0.14 12.1 2.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Roughex PF06020.11 OAJ09367.1 - 1.7 7.7 5.0 0.93 8.5 2.9 1.5 2 0 0 2 2 2 0 Drosophila roughex protein NAD_binding_10 PF13460.6 OAJ09373.1 - 3.1e-08 33.7 0.1 7.5e-07 29.2 0.1 2.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 OAJ09373.1 - 0.056 12.9 0.0 0.1 12.1 0.0 1.4 1 1 0 1 1 1 0 short chain dehydrogenase RVT_2 PF07727.14 OAJ09377.1 - 5.3e-73 245.6 0.0 7.6e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ09377.1 - 2.7e-19 69.5 0.0 7.6e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ09377.1 - 5.7e-06 26.0 0.1 1.7e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09377.1 - 4.3e-05 23.3 0.3 9.5e-05 22.2 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DDE_3 PF13358.6 OAJ09377.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-CCHC_3 PF13917.6 OAJ09378.1 - 0.0017 18.3 1.2 0.0032 17.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ09378.1 - 0.0037 17.3 4.5 0.0063 16.6 4.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ09378.1 - 0.005 16.5 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 OAJ09378.1 - 0.011 15.5 7.9 0.02 14.7 7.9 1.3 1 0 0 1 1 1 0 Zinc knuckle VbhA PF18495.1 OAJ09378.1 - 0.15 12.0 1.0 3.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Antitoxin VbhA zf-CCHC_5 PF14787.6 OAJ09378.1 - 0.26 11.0 8.5 0.071 12.8 4.9 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CENP-T_C PF15511.6 OAJ09384.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ09384.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ09384.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAJ09384.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ09384.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ09384.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HA2 PF04408.23 OAJ09385.1 - 3.2e-21 75.6 0.0 1.7e-20 73.3 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ09385.1 - 4.5e-15 55.8 0.0 1.4e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ09385.1 - 2.1e-13 50.6 0.0 4.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ09385.1 - 1.3e-08 34.8 0.1 2.5e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ09385.1 - 1.1e-06 28.9 0.1 2.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ09385.1 - 0.0015 18.9 0.1 0.0032 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ09385.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 OAJ09385.1 - 0.0066 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 OAJ09385.1 - 0.015 14.9 0.1 0.037 13.7 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 OAJ09385.1 - 0.016 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 OAJ09385.1 - 0.036 14.1 0.2 0.3 11.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ09385.1 - 0.04 13.4 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ09385.1 - 0.046 14.1 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.6 OAJ09385.1 - 0.047 13.8 0.1 0.3 11.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 OAJ09385.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 OAJ09385.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAJ09385.1 - 0.12 11.9 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 OAJ09385.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ09385.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain RAP1 PF07218.11 OAJ09385.1 - 1.7 6.8 4.1 2.8 6.1 4.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPP4R2 PF09184.11 OAJ09386.1 - 0.2 11.2 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 PPP4R2 PTS_2-RNA PF01885.16 OAJ09390.1 - 1.5e-49 168.5 0.0 2.6e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family GLTP PF08718.11 OAJ09391.1 - 4.3e-49 166.6 0.0 6.2e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ribosomal_L24e PF01246.20 OAJ09392.1 - 4.5e-31 106.9 0.6 4.5e-31 106.9 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e CLTH PF10607.9 OAJ09393.1 - 2.2e-26 92.5 0.0 3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAJ09393.1 - 1.8e-10 40.4 0.5 3.4e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 LisH Ribosomal_60s PF00428.19 OAJ09393.1 - 0.00029 21.4 12.4 0.00064 20.3 12.4 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein LAT PF15234.6 OAJ09393.1 - 0.026 14.2 1.9 0.032 14.0 0.5 1.7 2 0 0 2 2 2 0 Linker for activation of T-cells NOA36 PF06524.12 OAJ09393.1 - 1 8.6 6.3 1.4 8.2 6.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF3824 PF12868.7 OAJ09393.1 - 5.3 7.7 6.5 8.1 7.1 6.5 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Transposase_21 PF02992.14 OAJ09397.1 - 4.1e-05 22.9 0.0 8.2e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Leucyl-specific PF14795.6 OAJ09397.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain Radial_spoke PF04712.12 OAJ09398.1 - 0.089 11.7 0.2 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.6 OAJ09398.1 - 0.12 12.0 1.2 0.22 11.2 0.5 1.8 2 0 0 2 2 2 0 FAM176 family Cwf_Cwc_15 PF04889.12 OAJ09398.1 - 3.1 7.4 8.5 4.8 6.8 8.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LSM PF01423.22 OAJ09399.1 - 3e-22 78.1 0.1 3.7e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 OAJ09399.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DUF4006 PF13179.6 OAJ09403.1 - 1 9.3 3.2 0.29 11.1 0.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Retrotran_gag_2 PF14223.6 OAJ09409.1 - 2.1e-10 40.4 0.0 3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DDE_Tnp_4 PF13359.6 OAJ09415.1 - 1.6e-21 76.7 0.0 1.6e-21 76.7 0.0 2.0 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ09415.1 - 0.013 15.2 0.1 0.013 15.2 0.1 2.8 3 0 0 3 3 3 0 Transposase DDE domain Macoilin PF09726.9 OAJ09416.1 - 1.4 7.4 8.6 0.3 9.6 5.6 1.5 2 0 0 2 2 2 0 Macoilin family TPR_2 PF07719.17 OAJ09423.1 - 1.4e-06 27.9 6.3 0.029 14.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ09423.1 - 7.1e-06 25.6 5.0 0.027 14.3 0.1 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ09423.1 - 5.5e-05 23.4 21.0 0.16 12.3 0.9 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ09423.1 - 0.00023 21.1 3.0 0.17 12.2 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ09423.1 - 0.0013 18.9 0.6 3.3 7.8 0.1 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 OAJ09423.1 - 0.0073 16.8 4.1 4.1 8.0 0.6 4.3 3 1 0 3 3 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ09423.1 - 0.027 14.5 7.5 0.03 14.4 0.1 4.0 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 DUF1204 PF06721.11 OAJ09423.1 - 0.077 12.4 0.3 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) VIR_N PF15912.5 OAJ09423.1 - 0.12 11.9 2.1 0.19 11.3 2.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal TPR_7 PF13176.6 OAJ09423.1 - 0.13 12.3 2.5 15 5.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 OAJ09423.1 - 0.14 12.2 0.3 0.49 10.4 0.1 2.0 2 0 0 2 2 2 0 Putative TPR-like repeat ANAPC3 PF12895.7 OAJ09423.1 - 0.15 12.3 0.6 12 6.3 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ09423.1 - 0.4 11.6 20.3 0.7 10.9 0.0 7.3 5 2 2 7 7 7 0 Tetratricopeptide repeat NRDE-2 PF08424.10 OAJ09423.1 - 2.2 7.3 7.0 0.06 12.5 0.5 1.8 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_10 PF13374.6 OAJ09423.1 - 2.5 8.1 13.3 4.2 7.4 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ09423.1 - 2.6 8.9 21.4 2.8 8.8 0.1 6.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ09423.1 - 5.2 7.3 15.8 0.49 10.6 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat RNase_PH PF01138.21 OAJ09427.1 - 2.8e-11 44.0 0.1 5.3e-11 43.1 0.1 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4121 PF13497.6 OAJ09429.1 - 0.025 13.8 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Glyco_tranf_2_3 PF13641.6 OAJ09437.1 - 4.3e-30 105.3 0.0 6.2e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ09437.1 - 1.7e-09 37.4 0.1 1.9e-08 33.9 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ09437.1 - 3.5e-09 36.7 0.0 5.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 OAJ09437.1 - 0.22 11.4 12.4 0.011 15.6 6.0 2.1 2 1 0 2 2 2 0 Glycosyl transferase family group 2 Pkinase PF00069.25 OAJ09445.1 - 2.4e-49 168.1 5.4 2.4e-49 168.1 0.0 3.3 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09445.1 - 9.5e-22 77.5 0.0 9.5e-22 77.5 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase HEM4 PF02602.15 OAJ09450.1 - 2.5e-18 66.3 0.4 3.9e-09 36.2 0.1 4.6 5 0 0 5 5 5 4 Uroporphyrinogen-III synthase HemD SUIM_assoc PF16619.5 OAJ09450.1 - 0.15 12.2 4.4 0.77 9.9 4.4 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Helicase_C PF00271.31 OAJ09451.1 - 2e-17 63.5 0.0 9.6e-17 61.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ09451.1 - 1.7e-14 54.0 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ09451.1 - 1.1e-11 45.0 0.0 2.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ09451.1 - 1.3e-05 25.5 0.2 9.9e-05 22.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain Dicer_dimer PF03368.14 OAJ09451.1 - 7.4e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.23 OAJ09451.1 - 0.004 15.9 1.2 0.0056 15.4 0.5 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 OAJ09451.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 OAJ09451.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATP-sulfurylase PF01747.17 OAJ09457.1 - 2.1e-88 295.3 0.4 3.3e-88 294.7 0.4 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 OAJ09457.1 - 6.5e-54 182.1 0.0 1.1e-53 181.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 OAJ09457.1 - 4.9e-51 172.5 0.0 8.6e-51 171.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 OAJ09457.1 - 0.14 12.4 0.0 0.5 10.5 0.0 2.0 1 1 0 1 1 1 0 Cytidylyltransferase-like Zip PF02535.22 OAJ09458.1 - 5.6 6.1 9.7 10 5.2 9.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Smg8_Smg9 PF10220.9 OAJ09458.1 - 7 4.8 15.1 12 4.0 15.1 1.3 1 0 0 1 1 1 0 Smg8_Smg9 DUF3390 PF11870.8 OAJ09462.1 - 0.076 13.4 0.2 0.19 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) RALF PF05498.11 OAJ09463.1 - 0.024 15.6 0.1 0.38 11.8 0.1 2.1 1 1 1 2 2 2 0 Rapid ALkalinization Factor (RALF) Aldedh PF00171.22 OAJ09471.1 - 2.7e-156 520.7 0.4 3.1e-156 520.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 OAJ09472.1 - 3.8e-67 226.4 0.0 4.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ09472.1 - 1.4e-33 116.3 0.0 4.5e-33 114.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ09472.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ09472.1 - 0.0041 16.1 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ09472.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ09472.1 - 0.088 12.7 0.1 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ09472.1 - 0.1 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 OAJ09472.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC NEMP PF10225.9 OAJ09478.1 - 0.01 15.5 0.0 0.045 13.4 0.0 1.8 2 0 0 2 2 2 0 NEMP family UL42 PF17638.2 OAJ09478.1 - 5.2 7.1 7.8 1.3 9.0 1.0 2.9 2 1 1 3 3 3 0 HCMV UL42 Glyco_hydro_45 PF02015.16 OAJ09483.1 - 4.9e-51 173.6 8.5 5.7e-51 173.4 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Glyco_hydro_45 PF02015.16 OAJ09484.1 - 2.2e-24 86.6 0.3 3e-24 86.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.14 OAJ09484.1 - 0.46 9.9 9.9 0.66 9.3 9.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Asn_synthase PF00733.21 OAJ09489.1 - 2.3e-08 34.1 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase tRNA-synt_2d PF01409.20 OAJ09490.1 - 9.3e-43 146.5 0.2 3.1e-25 89.1 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 OAJ09490.1 - 4.6e-23 81.4 0.0 1.2e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF883 PF05957.13 OAJ09491.1 - 0.072 13.7 0.4 0.072 13.7 0.4 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Nop14 PF04147.12 OAJ09491.1 - 0.29 9.3 5.4 0.59 8.3 5.4 1.5 1 0 0 1 1 1 0 Nop14-like family Adap_comp_sub PF00928.21 OAJ09492.1 - 6.7e-61 206.0 0.1 1.5e-60 204.8 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ09492.1 - 4.3e-08 33.2 0.1 7.3e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NUP214 PF16755.5 OAJ09496.1 - 0.00017 20.9 0.0 0.00085 18.7 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ATG16 PF08614.11 OAJ09499.1 - 0.00081 19.7 9.4 0.001 19.3 9.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 OAJ09499.1 - 0.0015 18.6 11.6 0.0023 18.0 11.6 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 OAJ09499.1 - 0.0018 19.0 2.0 0.0028 18.4 1.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4472) CC2-LZ PF16516.5 OAJ09499.1 - 0.0039 17.5 3.2 0.13 12.6 0.5 2.2 1 1 1 2 2 2 2 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 OAJ09499.1 - 0.0055 15.6 2.4 0.007 15.3 2.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HMMR_N PF15905.5 OAJ09499.1 - 0.0085 15.6 1.6 0.0097 15.4 1.6 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 OAJ09499.1 - 0.0088 16.5 1.9 0.0097 16.4 1.9 1.1 1 0 0 1 1 1 1 Fez1 MscS_porin PF12795.7 OAJ09499.1 - 0.013 15.0 9.7 0.02 14.5 9.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain JIP_LZII PF16471.5 OAJ09499.1 - 0.02 15.1 1.9 1.7 8.9 0.3 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II HAP1_N PF04849.13 OAJ09499.1 - 0.023 13.9 2.5 0.027 13.7 2.5 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ABC_tran_CTD PF16326.5 OAJ09499.1 - 0.028 14.7 9.8 0.82 10.0 3.3 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain ADIP PF11559.8 OAJ09499.1 - 0.029 14.5 6.2 0.33 11.0 3.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 OAJ09499.1 - 0.032 14.2 5.1 0.22 11.5 4.8 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Alpha-2-MRAP_C PF06401.11 OAJ09499.1 - 0.033 14.2 0.6 0.039 13.9 0.6 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Spectrin PF00435.21 OAJ09499.1 - 0.053 14.0 3.7 0.08 13.4 3.7 1.3 1 0 0 1 1 1 0 Spectrin repeat Atg14 PF10186.9 OAJ09499.1 - 0.06 12.4 3.9 0.076 12.1 3.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOIP-UBA PF16678.5 OAJ09499.1 - 0.071 13.1 3.4 0.087 12.8 3.4 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair Golgin_A5 PF09787.9 OAJ09499.1 - 0.078 12.4 3.2 0.13 11.7 3.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 CCDC-167 PF15188.6 OAJ09499.1 - 0.091 13.1 2.8 0.13 12.6 1.6 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 GAS PF13851.6 OAJ09499.1 - 0.11 11.8 2.9 0.15 11.4 2.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 OAJ09499.1 - 0.15 12.7 0.7 0.68 10.6 0.4 1.9 1 1 2 3 3 3 0 Initiation control protein YabA DUF812 PF05667.11 OAJ09499.1 - 0.2 10.5 3.8 0.26 10.1 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HAUS-augmin3 PF14932.6 OAJ09499.1 - 0.27 10.8 4.3 0.33 10.5 4.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TMF_DNA_bd PF12329.8 OAJ09499.1 - 0.39 10.7 6.6 6.4 6.9 0.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.8 OAJ09499.1 - 0.42 10.2 7.7 0.57 9.8 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) BRE1 PF08647.11 OAJ09499.1 - 0.44 10.7 6.4 0.26 11.4 4.6 1.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GrpE PF01025.19 OAJ09499.1 - 0.47 10.1 3.9 2 8.1 4.0 1.7 1 1 0 1 1 1 0 GrpE DUF724 PF05266.14 OAJ09499.1 - 0.5 10.2 4.0 0.67 9.8 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Spc24 PF08286.11 OAJ09499.1 - 0.56 10.5 5.2 5.6 7.3 0.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Uso1_p115_C PF04871.13 OAJ09499.1 - 0.68 10.3 10.5 0.82 10.0 9.5 1.5 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 OAJ09499.1 - 0.88 8.9 7.6 1.4 8.2 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 OAJ09499.1 - 1.2 9.7 9.2 2.6 8.6 9.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-Q PF13094.6 OAJ09499.1 - 1.5 9.0 9.8 3.9 7.6 2.6 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_L10 PF00466.20 OAJ09504.1 - 0.001 19.2 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 DUF2169 PF09937.9 OAJ09504.1 - 0.093 12.2 0.5 0.16 11.4 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Transket_pyr PF02779.24 OAJ09505.1 - 3.3e-37 127.9 0.0 5.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ09505.1 - 2e-27 95.6 0.0 1.6e-26 92.6 0.0 2.2 1 1 0 1 1 1 1 Transketolase, C-terminal domain Ribosomal_S5 PF00333.20 OAJ09505.1 - 0.21 11.6 0.5 18 5.4 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Cullin PF00888.22 OAJ09512.1 - 2.7e-191 637.4 0.0 3.5e-191 637.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ09512.1 - 1.9e-28 98.3 0.4 4.4e-28 97.1 0.4 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 OAJ09512.1 - 0.025 14.9 0.3 0.096 13.0 0.0 2.3 2 0 0 2 2 2 0 Penicillinase repressor TrmB PF01978.19 OAJ09512.1 - 0.027 14.4 0.2 0.97 9.4 0.0 2.6 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB MIEAP PF16026.5 OAJ09512.1 - 0.063 13.5 0.6 3.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Mitochondria-eating protein TetR_C_29 PF17938.1 OAJ09512.1 - 0.1 12.7 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tyrosinase PF00264.20 OAJ09519.1 - 0.035 14.4 0.7 0.05 13.9 0.7 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase Apolipoprotein PF01442.18 OAJ09519.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Picorna_P3A PF06363.11 OAJ09519.1 - 0.16 11.9 5.8 24 4.9 0.1 3.6 1 1 2 3 3 3 0 Picornaviridae P3A protein Bmt2 PF11968.8 OAJ09524.1 - 1.3e-43 149.5 0.0 6.7e-26 91.5 0.0 2.2 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 RVT_3 PF13456.6 OAJ09526.1 - 0.0054 16.5 0.1 0.0081 16.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like UPF0183 PF03676.14 OAJ09532.1 - 2.2e-16 60.2 0.1 1.3e-07 31.3 0.3 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) PTCB-BRCT PF12738.7 OAJ09533.1 - 1.6e-29 101.6 3.3 1.7e-18 66.3 0.1 5.4 6 0 0 6 6 6 2 twin BRCT domain BRCT PF00533.26 OAJ09533.1 - 2.6e-28 98.2 0.0 1.2e-12 48.1 0.0 6.7 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 OAJ09533.1 - 5.8e-21 74.7 0.0 5.9e-05 23.4 0.0 7.5 6 2 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 OAJ09533.1 - 2.5e-12 46.6 0.2 1.4e-10 40.9 0.0 3.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 OAJ09533.1 - 1.7e-06 28.2 0.1 1.6 9.0 0.0 5.1 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain AIM5 PF17050.5 OAJ09533.1 - 0.14 13.0 3.1 1.1 10.2 3.1 2.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 PRIMA1 PF16101.5 OAJ09533.1 - 0.28 11.2 1.5 1 9.4 1.5 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SUIM_assoc PF16619.5 OAJ09533.1 - 0.36 10.9 6.4 0.13 12.3 1.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DnaJ PF00226.31 OAJ09536.1 - 2e-14 53.5 0.7 4.2e-14 52.4 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3699 PF12480.8 OAJ09536.1 - 0.067 13.4 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Ras PF00071.22 OAJ09537.1 - 2.4e-56 189.8 0.3 3e-56 189.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ09537.1 - 1.4e-33 115.6 0.1 2.1e-33 115.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ09537.1 - 3.1e-13 49.6 0.2 3.7e-13 49.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ09537.1 - 1.4e-05 24.8 0.2 3.3e-05 23.5 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ09537.1 - 0.00021 20.8 0.1 0.00025 20.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ09537.1 - 0.00085 19.4 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Lipase_GDSL_2 PF13472.6 OAJ09538.1 - 1.7e-05 25.3 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAJ09538.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NDC10_II PF16787.5 OAJ09542.1 - 7.4e-49 166.5 0.0 4.8e-30 104.7 0.0 2.2 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ09542.1 - 1.6e-15 57.1 0.2 3.2e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PI3K_1B_p101 PF10486.9 OAJ09548.1 - 0.0079 14.0 0.6 0.012 13.5 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roughex PF06020.11 OAJ09548.1 - 0.021 14.0 1.0 0.033 13.3 1.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 OAJ09548.1 - 0.41 9.9 3.1 0.69 9.2 3.1 1.4 1 0 0 1 1 1 0 NOA36 protein Tub_N PF16322.5 OAJ09548.1 - 0.52 10.7 5.2 0.14 12.6 1.3 2.0 2 0 0 2 2 2 0 Tubby N-terminal CENP-B_dimeris PF09026.10 OAJ09548.1 - 1.9 9.0 10.5 5.4 7.5 10.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4813 PF16072.5 OAJ09548.1 - 3.9 7.1 31.3 7.4 6.2 31.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) GREB1 PF15782.5 OAJ09548.1 - 8.8 3.3 6.1 12 2.8 6.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 OAJ09556.1 - 0.052 12.6 0.6 0.08 12.0 0.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 ICAP-1_inte_bdg PF10480.9 OAJ09556.1 - 2.7 7.9 7.6 3.7 7.5 7.6 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein AMP-binding PF00501.28 OAJ09563.1 - 3.9e-73 246.5 0.0 2.1e-49 168.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ09563.1 - 5.4e-10 40.1 0.5 1.1e-08 35.9 0.0 3.1 3 1 0 3 3 3 1 AMP-binding enzyme C-terminal domain UDPGP PF01704.18 OAJ09564.1 - 8.6e-33 113.6 0.0 1e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MRP-L20 PF12824.7 OAJ09575.1 - 1.9e-18 67.2 0.1 3.1e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 GntR PF00392.21 OAJ09575.1 - 0.15 11.8 0.1 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family BAT2_N PF07001.11 OAJ09577.1 - 2.2 8.7 10.2 0.26 11.7 1.3 2.2 2 0 0 2 2 2 0 BAT2 N-terminus WD40 PF00400.32 OAJ09582.1 - 2.3e-18 66.2 3.9 0.00019 22.1 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09582.1 - 5e-09 36.3 0.0 4.2e-05 23.8 0.0 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ09582.1 - 4.8e-05 23.3 0.0 0.011 15.6 0.0 2.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 OAJ09582.1 - 0.022 14.1 0.0 0.095 12.0 0.0 2.0 3 0 0 3 3 3 0 WD40-like domain DcpS_C PF11969.8 OAJ09583.1 - 7.3e-21 74.8 0.7 1.5e-20 73.8 0.7 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ09583.1 - 1.5e-08 35.3 3.4 6.4e-08 33.2 3.4 1.8 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 OAJ09583.1 - 0.0097 15.8 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Dimer_Tnp_hAT PF05699.14 OAJ09592.1 - 9e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NDC10_II PF16787.5 OAJ09593.1 - 5.3e-13 48.7 0.0 7.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ09593.1 - 0.00088 19.6 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sigma70_ner PF04546.13 OAJ09595.1 - 1.5 8.7 3.9 6.3 6.6 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region BNIP2 PF12496.8 OAJ09595.1 - 1.8 9.0 7.0 0.45 11.0 1.0 2.3 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF4805 PF16063.5 OAJ09603.1 - 0.017 14.5 3.8 0.34 10.2 4.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) DUF3439 PF11921.8 OAJ09603.1 - 0.037 14.0 0.9 0.046 13.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ADH_N PF08240.12 OAJ09609.1 - 2.5e-27 94.9 4.1 4.3e-27 94.2 4.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ09609.1 - 6.3e-17 61.8 0.0 9.7e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ09609.1 - 0.015 14.7 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 OAJ09609.1 - 0.043 14.9 0.0 0.078 14.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase An_peroxidase PF03098.15 OAJ09610.1 - 4.2e-05 22.3 0.0 6.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase UCH PF00443.29 OAJ09613.1 - 4.5e-38 131.2 0.0 5.9e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ09613.1 - 0.00013 21.7 0.0 0.011 15.3 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SUZ PF12752.7 OAJ09614.1 - 4.7e-10 40.1 13.2 4.7e-10 40.1 13.2 8.3 9 1 0 9 9 9 1 SUZ domain R3H PF01424.22 OAJ09614.1 - 7.2e-06 25.9 0.1 1.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 R3H domain SNF2_N PF00176.23 OAJ09623.1 - 3e-53 180.8 0.0 4.8e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 OAJ09623.1 - 3.5e-41 141.4 0.0 6.5e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 OAJ09623.1 - 3.8e-13 49.7 0.0 8.6e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ09623.1 - 1.5e-06 28.3 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ09623.1 - 0.00039 20.2 0.0 0.0091 15.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 OAJ09623.1 - 0.0017 17.6 0.0 0.024 13.8 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-CCHC_2 PF13696.6 OAJ09623.1 - 1 9.3 3.9 0.51 10.2 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle ERAP1_C PF11838.8 OAJ09624.1 - 5.6e-74 249.5 0.1 8e-74 249.0 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ09624.1 - 3.4e-25 88.9 0.0 4.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Tex_N PF09371.10 OAJ09624.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain DUF4478 PF14793.6 OAJ09631.1 - 0.79 9.6 5.5 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Ribosomal_L5_C PF00673.21 OAJ09633.1 - 4e-20 71.8 0.0 7.3e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAJ09633.1 - 4.7e-19 68.5 0.0 7.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 Prefoldin_2 PF01920.20 OAJ09634.1 - 3.1e-21 75.3 14.1 4e-21 74.9 14.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.12 OAJ09634.1 - 9.9e-05 22.7 5.6 0.068 13.6 0.1 2.1 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 OAJ09634.1 - 0.011 16.2 17.1 0.051 14.1 5.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region OmdA PF13376.6 OAJ09634.1 - 0.028 14.4 0.2 0.075 13.1 0.2 1.9 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SlyX PF04102.12 OAJ09634.1 - 0.03 15.0 1.2 0.03 15.0 1.2 2.5 2 1 0 2 2 2 0 SlyX Lzipper-MIP1 PF14389.6 OAJ09634.1 - 0.053 13.8 9.5 0.33 11.3 7.9 2.3 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Fib_alpha PF08702.10 OAJ09634.1 - 0.061 13.5 12.5 0.6 10.3 12.5 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 OAJ09634.1 - 0.069 13.2 14.6 0.44 10.7 2.2 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 OAJ09634.1 - 0.085 11.4 13.1 0.099 11.2 13.1 1.0 1 0 0 1 1 1 0 Macoilin family Med4 PF10018.9 OAJ09634.1 - 0.086 12.5 0.2 0.086 12.5 0.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 UPF0242 PF06785.11 OAJ09634.1 - 0.089 12.9 15.2 0.13 12.3 15.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AATF-Che1 PF13339.6 OAJ09634.1 - 0.1 13.3 7.3 0.17 12.6 7.2 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 OAJ09634.1 - 0.13 11.6 12.9 0.049 13.0 2.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) FPP PF05911.11 OAJ09634.1 - 0.14 10.3 12.8 0.17 10.0 12.8 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 OAJ09634.1 - 0.17 10.7 17.2 0.3 9.9 17.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Nas2_N PF18265.1 OAJ09634.1 - 0.18 11.7 3.1 1.3 9.0 0.1 2.8 2 2 0 2 2 2 0 Nas2 N_terminal domain FlxA PF14282.6 OAJ09634.1 - 0.19 11.7 15.7 0.28 11.2 2.0 2.2 2 0 0 2 2 2 0 FlxA-like protein IHO1 PF15771.5 OAJ09634.1 - 0.2 10.4 7.4 0.045 12.5 3.8 1.5 1 1 0 2 2 2 0 Interactor of HORMAD1 protein 1 Tmpp129 PF10272.9 OAJ09634.1 - 0.21 10.9 3.8 0.14 11.4 0.7 1.8 1 1 1 2 2 2 0 Putative transmembrane protein precursor Cep57_MT_bd PF06657.13 OAJ09634.1 - 0.23 11.9 10.0 0.34 11.4 1.7 2.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.10 OAJ09634.1 - 0.25 11.2 1.9 8.4 6.3 0.3 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 kleA_kleC PF17383.2 OAJ09634.1 - 0.33 11.3 2.9 0.53 10.6 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A KMP11 PF03037.16 OAJ09634.1 - 0.44 11.4 4.4 1.6 9.6 4.4 1.9 1 1 0 1 1 1 0 Kinetoplastid membrane protein 11 DUF1664 PF07889.12 OAJ09634.1 - 0.45 10.6 8.7 1.3 9.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 OAJ09634.1 - 0.46 10.7 14.6 2.6 8.3 3.6 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Uds1 PF15456.6 OAJ09634.1 - 0.56 10.4 9.2 1.1 9.4 9.2 1.7 1 1 0 1 1 1 0 Up-regulated During Septation JIP_LZII PF16471.5 OAJ09634.1 - 0.57 10.4 9.4 0.16 12.2 0.9 2.7 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II Occludin_ELL PF07303.13 OAJ09634.1 - 0.61 10.9 7.5 3 8.6 1.7 2.2 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 OAJ09634.1 - 0.63 9.1 10.2 1.5 7.9 10.2 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OAJ09634.1 - 0.66 9.3 18.6 2.9 7.2 18.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rootletin PF15035.6 OAJ09634.1 - 0.72 9.8 11.4 2.9 7.9 11.4 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF5082 PF16888.5 OAJ09634.1 - 0.73 10.1 11.4 2.1 8.7 11.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 OAJ09634.1 - 0.82 9.0 10.6 6.9 6.0 10.7 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus V-ATPase_C PF03223.15 OAJ09634.1 - 0.85 9.0 7.6 1.4 8.3 7.6 1.3 1 1 0 1 1 1 0 V-ATPase subunit C Baculo_PEP_C PF04513.12 OAJ09634.1 - 0.93 9.5 6.7 2.1 8.4 0.6 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 OAJ09634.1 - 0.94 9.5 11.2 0.41 10.7 1.6 2.1 1 1 1 2 2 2 0 Laminin Domain II PKcGMP_CC PF16808.5 OAJ09634.1 - 0.95 9.4 7.2 0.18 11.7 1.6 2.4 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HR1 PF02185.16 OAJ09634.1 - 1.2 9.3 10.8 4.6 7.4 0.9 2.5 2 1 0 2 2 2 0 Hr1 repeat End3 PF12761.7 OAJ09634.1 - 1.2 9.2 12.3 1.5 9.0 12.3 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Peptidase_S46 PF10459.9 OAJ09634.1 - 1.2 7.7 8.1 1.5 7.4 8.1 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF724 PF05266.14 OAJ09634.1 - 1.4 8.7 14.4 91 2.8 14.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) YabA PF06156.13 OAJ09634.1 - 1.4 9.6 11.0 2.2e+02 2.5 11.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 OAJ09634.1 - 1.8 8.6 15.5 0.96 9.5 6.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mto2_bdg PF12808.7 OAJ09634.1 - 2 8.7 10.0 14 6.1 0.5 3.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2205 PF10224.9 OAJ09634.1 - 2.1 8.4 16.0 0.1 12.6 3.4 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DUF641 PF04859.12 OAJ09634.1 - 2.5 8.5 13.2 0.95 9.8 5.3 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Phlebovirus_NSM PF07246.11 OAJ09634.1 - 2.7 7.3 7.0 3.6 6.9 7.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DHR10 PF18595.1 OAJ09634.1 - 2.8 8.0 17.5 11 6.2 17.5 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 OAJ09634.1 - 3 8.3 12.5 3 8.3 10.7 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 OAJ09634.1 - 3 8.2 16.2 3.2 8.1 2.1 2.1 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPD52 PF04201.15 OAJ09634.1 - 3.4 7.2 9.2 0.58 9.7 2.5 2.2 1 1 1 2 2 2 0 Tumour protein D52 family Allexi_40kDa PF05549.11 OAJ09634.1 - 4.1 6.8 6.5 2.3 7.6 2.3 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc24 PF08286.11 OAJ09634.1 - 4.6 7.5 15.0 5.4 7.3 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 OAJ09634.1 - 4.9 7.5 15.6 8.2 6.8 2.6 3.2 2 2 1 3 3 3 0 ABC transporter C-terminal domain OmpH PF03938.14 OAJ09634.1 - 6.2 7.2 20.4 27 5.1 20.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 OAJ09634.1 - 6.5 6.7 15.0 0.96 9.4 4.5 2.7 2 1 1 3 3 3 0 Prefoldin subunit ALS_ss_C PF10369.9 OAJ09635.1 - 2.8e-18 65.9 0.0 2.3e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 OAJ09635.1 - 5.7e-13 48.4 0.1 9.8e-13 47.6 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 OAJ09635.1 - 1.2e-07 31.5 0.1 3.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 ACT domain MEIOC PF15189.6 OAJ09635.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC SOG2 PF10428.9 OAJ09635.1 - 0.69 9.1 10.6 1.1 8.4 10.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RT_RNaseH PF17917.1 OAJ09639.1 - 3.9e-11 43.2 0.0 6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09639.1 - 6.3e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage-tail_3 PF13550.6 OAJ09639.1 - 0.039 13.8 0.4 0.082 12.8 0.1 1.7 2 0 0 2 2 2 0 Putative phage tail protein Oxygenase-NA PF09859.9 OAJ09639.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA RVT_1 PF00078.27 OAJ09640.1 - 5.9e-20 71.7 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ09640.1 - 4.6e-16 58.7 0.0 9.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ09640.1 - 4.8e-13 49.0 0.0 1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ09640.1 - 0.0082 16.3 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ09640.1 - 0.0098 16.2 0.0 0.044 14.1 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase TPR_8 PF13181.6 OAJ09640.1 - 0.05 13.8 1.1 37 4.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ09640.1 - 0.56 9.5 4.2 4.3 6.6 0.1 2.5 2 0 0 2 2 2 0 MalT-like TPR region Hap4_Hap_bind PF10297.9 OAJ09640.1 - 1.5 9.0 5.0 5.1 7.4 0.9 2.6 2 0 0 2 2 2 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Formyl_trans_N PF00551.19 OAJ09645.1 - 3.4e-29 101.9 0.0 8.8e-29 100.5 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase CAP PF00188.26 OAJ09646.1 - 2.5e-18 67.1 0.7 4.5e-18 66.3 0.7 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Tyrosinase PF00264.20 OAJ09646.1 - 0.016 15.5 1.0 0.024 15.0 1.0 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF5349 PF17298.2 OAJ09646.1 - 4.9 6.8 10.0 7.1 6.3 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) GMC_oxred_N PF00732.19 OAJ09651.1 - 8.9e-48 163.2 0.0 1.2e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ09651.1 - 2.1e-36 125.6 0.0 3.5e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 OAJ09651.1 - 4.2e-05 23.0 0.4 0.037 13.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ09651.1 - 0.00018 20.7 0.1 0.00027 20.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ09651.1 - 0.0003 21.0 0.1 0.00079 19.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ09651.1 - 0.00036 19.7 0.4 0.0084 15.2 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 OAJ09651.1 - 0.00091 18.9 0.1 0.0062 16.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ09651.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ09651.1 - 0.0035 16.6 0.1 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ09651.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Selenoprotein_S PF06936.11 OAJ09652.1 - 0.12 12.2 0.2 0.13 12.1 0.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Peptidase_S10 PF00450.22 OAJ09659.1 - 3.9e-70 237.4 0.0 5.8e-70 236.8 0.0 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase MPC PF03650.13 OAJ09664.1 - 8.4e-36 122.5 0.1 1.1e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Pex19 PF04614.12 OAJ09665.1 - 5.3e-56 190.1 4.7 3.1e-55 187.6 4.7 1.9 1 1 0 1 1 1 1 Pex19 protein family DUF1018 PF06252.12 OAJ09665.1 - 0.039 14.9 0.0 35 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) GCIP PF13324.6 OAJ09665.1 - 0.044 13.4 4.9 1.4 8.5 2.5 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting HBS1_N PF08938.10 OAJ09665.1 - 5.3 7.4 7.7 0.52 10.6 1.8 2.4 3 0 0 3 3 3 0 HBS1 N-terminus CCDC53 PF10152.9 OAJ09665.1 - 6.8 7.1 9.4 0.42 11.0 3.3 2.0 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex ALAD PF00490.21 OAJ09666.1 - 3e-119 397.9 0.0 3.5e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Retrotrans_gag PF03732.17 OAJ09671.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein rhaM PF05336.13 OAJ09671.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 L-rhamnose mutarotase RVT_1 PF00078.27 OAJ09672.1 - 4.9e-22 78.5 0.0 8.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09672.1 - 9.8e-15 54.4 0.0 2.9e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09672.1 - 1.6e-12 47.7 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ09672.1 - 5.3e-06 26.4 0.1 1.1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ09672.1 - 0.0061 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ09672.1 - 0.02 15.5 0.1 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09672.1 - 0.17 12.5 0.0 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease THEG PF14912.6 OAJ09676.1 - 0.085 13.3 1.2 0.17 12.4 1.2 1.6 1 1 0 1 1 1 0 Testicular haploid expressed repeat FTR1 PF03239.14 OAJ09677.1 - 0.0067 15.6 0.4 0.008 15.4 0.4 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3262 PF11660.8 OAJ09677.1 - 0.012 16.0 2.9 0.025 14.9 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3262) DUF485 PF04341.12 OAJ09677.1 - 0.053 13.5 0.6 0.058 13.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 UCR_TM PF02921.14 OAJ09678.1 - 7.7e-12 45.5 3.0 3.8e-11 43.3 3.0 2.2 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 OAJ09678.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pex2_Pex12 PF04757.14 OAJ09679.1 - 4.1e-22 78.9 0.2 4.7e-22 78.7 0.2 1.0 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region CDRN PF05174.12 OAJ09679.1 - 0.11 12.3 0.8 3.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus Muted PF14942.6 OAJ09686.1 - 1 9.7 5.3 2 8.7 5.3 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Gti1_Pac2 PF09729.9 OAJ09697.1 - 2.2e-27 96.3 2.6 3.7e-25 89.1 0.1 7.0 5 3 1 6 6 6 3 Gti1/Pac2 family RVT_1 PF00078.27 OAJ09704.1 - 2.2e-25 89.5 0.0 4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09704.1 - 1.2e-20 73.4 0.1 1.3e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ09704.1 - 2.3e-15 56.7 0.0 2e-10 40.9 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09704.1 - 3.8e-14 52.5 0.0 7.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ09704.1 - 4.7e-08 33.2 0.1 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09704.1 - 0.028 15.1 0.1 0.12 13.0 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease RVP PF00077.20 OAJ09704.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Myb_DNA-binding PF00249.31 OAJ09714.1 - 5.7e-11 42.4 0.2 2.9e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ09714.1 - 0.015 15.2 1.6 0.3 11.0 0.0 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Tri3 PF07428.11 OAJ09719.1 - 2.2e-06 26.8 0.0 1.4e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Tetraspanin PF00335.20 OAJ09720.1 - 0.00065 19.5 10.7 0.00065 19.5 10.7 1.7 1 1 1 2 2 2 1 Tetraspanin family TMEM51 PF15345.6 OAJ09720.1 - 0.022 14.6 0.4 0.5 10.2 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 COX4_pro_2 PF07835.12 OAJ09720.1 - 0.052 13.7 0.4 0.052 13.7 0.4 3.0 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV MIG-14_Wnt-bd PF06664.12 OAJ09720.1 - 0.1 11.8 8.0 0.075 12.2 6.4 1.5 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion EphA2_TM PF14575.6 OAJ09720.1 - 1.3 9.9 8.6 1.7 9.6 0.0 3.6 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain VWA PF00092.28 OAJ09721.1 - 0.00051 20.3 0.0 0.012 15.9 0.0 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAJ09721.1 - 0.027 15.1 0.0 0.084 13.5 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain ANAPC15 PF15243.6 OAJ09729.1 - 0.01 16.2 3.0 0.024 15.0 3.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop14 PF04147.12 OAJ09729.1 - 0.97 7.6 3.2 1.3 7.1 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ09729.1 - 1.1 8.5 6.8 1.9 7.7 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ09729.1 - 4.4 5.3 7.5 5.8 4.9 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribonucleas_3_3 PF14622.6 OAJ09735.1 - 1.5e-06 28.4 0.0 0.14 12.4 0.0 3.2 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 OAJ09735.1 - 7e-05 23.4 0.0 0.00019 22.0 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 OAJ09735.1 - 0.085 13.6 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif WD40 PF00400.32 OAJ09736.1 - 1.2e-37 127.3 12.7 2.1e-10 41.0 0.6 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ09736.1 - 3.2e-12 46.6 0.7 0.0054 17.0 0.0 4.4 3 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ09736.1 - 0.00039 19.5 0.0 5.5 5.9 0.0 4.6 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 OAJ09736.1 - 0.00069 18.6 0.1 0.0018 17.3 0.1 1.7 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 OAJ09736.1 - 0.0022 16.7 4.3 1.1 7.9 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 OAJ09736.1 - 0.0041 16.5 1.7 0.26 10.5 0.2 3.8 4 1 1 5 5 5 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ndc1_Nup PF09531.10 OAJ09736.1 - 0.027 13.2 0.8 0.044 12.5 0.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 OAJ09736.1 - 2.3 8.1 5.7 3.3 7.6 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) IPPT PF01715.17 OAJ09737.1 - 7.9e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 OAJ09737.1 - 0.004 17.4 0.0 0.0045 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ09737.1 - 0.0057 17.2 0.1 0.0058 17.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 OAJ09737.1 - 0.01 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 OAJ09737.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain IPT PF01745.16 OAJ09737.1 - 0.016 14.6 0.4 0.23 10.8 0.4 2.0 1 1 0 1 1 1 0 Isopentenyl transferase AAA_28 PF13521.6 OAJ09737.1 - 0.016 15.5 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ09737.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 OAJ09737.1 - 0.032 14.4 0.0 0.032 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_L2_C PF03947.18 OAJ09737.1 - 0.035 14.3 0.0 0.058 13.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain AAA_25 PF13481.6 OAJ09737.1 - 0.076 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ09737.1 - 0.097 11.8 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Semialdhyde_dh PF01118.24 OAJ09737.1 - 0.12 12.8 0.1 0.16 12.4 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L35Ae PF01247.18 OAJ09738.1 - 1e-40 137.8 0.3 1.1e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 OAJ09738.1 - 0.059 13.6 0.1 9.3 6.5 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain SWIB PF02201.18 OAJ09741.1 - 4.5e-29 100.1 0.0 7.1e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 OAJ09741.1 - 5.3e-08 32.7 2.2 3.4e-06 26.9 0.7 3.2 3 0 0 3 3 3 1 DEK C terminal domain TFIIF_alpha PF05793.12 OAJ09741.1 - 4.3 5.8 11.1 0.31 9.6 4.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LSM PF01423.22 OAJ09742.1 - 8.4e-17 60.6 0.1 1e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF5497 PF17601.2 OAJ09742.1 - 0.034 14.4 0.0 0.044 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5497) eIF2A PF08662.11 OAJ09748.1 - 4.3e-39 134.4 0.4 1.7e-34 119.4 0.0 4.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 OAJ09748.1 - 1.1e-06 28.9 0.2 48 4.3 0.0 7.3 5 3 2 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 OAJ09748.1 - 3.7e-06 26.7 0.1 8e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 OAJ09748.1 - 0.0057 17.5 3.1 1.6 9.8 0.0 5.2 5 1 1 6 6 6 1 WD domain, G-beta repeat DPPIV_N PF00930.21 OAJ09748.1 - 0.029 13.1 0.1 3.3 6.4 0.0 3.3 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Phage_integrase PF00589.22 OAJ09754.1 - 1.5e-05 24.9 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3504 PF12012.8 OAJ09754.1 - 0.05 13.5 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) zf-CCHC PF00098.23 OAJ09762.1 - 3.6e-06 26.8 1.7 3.6e-06 26.8 1.7 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ09762.1 - 0.0005 19.8 0.6 0.00091 19.0 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ09762.1 - 0.045 13.5 0.3 0.081 12.6 0.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 OAJ09762.1 - 0.13 12.0 0.9 0.21 11.4 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 OAJ09763.1 - 3.2e-15 56.4 0.0 5.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09763.1 - 8.5e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09763.1 - 0.00051 19.8 0.1 0.016 14.9 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain RVT_2 PF07727.14 OAJ09764.1 - 7.9e-44 150.1 0.0 1.2e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YejG PF13989.6 OAJ09764.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 YejG-like protein Myb_DNA-bind_3 PF12776.7 OAJ09770.1 - 0.024 15.6 0.1 0.048 14.6 0.1 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.17 OAJ09771.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein Shugoshin_N PF07558.11 OAJ09771.1 - 0.041 13.8 0.0 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.9 OAJ09771.1 - 0.12 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF4692 PF15763.5 OAJ09771.1 - 3 8.3 6.4 6.3 7.2 6.4 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) DDE_Tnp_4 PF13359.6 OAJ09772.1 - 1.8e-23 82.9 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ09772.1 - 1e-06 28.5 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 OAJ09772.1 - 4.5e-06 26.4 0.1 9.2e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein PV-1 PF06637.11 OAJ09776.1 - 0.033 13.0 7.1 0.038 12.8 7.1 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) WD40_alt PF14077.6 OAJ09776.1 - 0.038 13.9 0.3 0.092 12.6 0.3 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif Syntaxin-6_N PF09177.11 OAJ09776.1 - 0.096 13.3 4.9 0.12 12.9 4.9 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF2207 PF09972.9 OAJ09776.1 - 0.16 10.7 0.5 0.17 10.6 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GPS2_interact PF15784.5 OAJ09776.1 - 0.29 11.6 7.0 0.5 10.8 7.0 1.6 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Nup88 PF10168.9 OAJ09776.1 - 0.33 8.7 4.6 0.39 8.5 4.6 1.0 1 0 0 1 1 1 0 Nuclear pore component T2SSM PF04612.12 OAJ09776.1 - 0.54 10.3 5.1 4.9 7.2 2.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4207 PF13904.6 OAJ09781.1 - 0.066 12.9 4.8 0.1 12.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Arm-DNA-bind_2 PF12167.8 OAJ09783.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Arm DNA-binding domain DUF5127 PF17168.4 OAJ09795.1 - 6.9e-24 84.9 0.7 9.8e-24 84.4 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ09795.1 - 8.5e-08 31.6 1.8 0.009 15.5 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ09795.1 - 0.016 14.7 0.1 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term UQ_con PF00179.26 OAJ09801.1 - 1.7e-16 60.1 0.0 1.8e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 OAJ09801.1 - 0.024 14.9 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain Ribonuc_P_40 PF08584.11 OAJ09802.1 - 1.1e-42 146.3 0.0 2.8e-25 89.2 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit CDC45 PF02724.14 OAJ09802.1 - 0.15 10.4 6.2 0.22 9.8 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.8 OAJ09802.1 - 0.34 10.3 3.2 0.63 9.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Nop14 PF04147.12 OAJ09802.1 - 1.2 7.3 7.3 1.7 6.8 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 OAJ09802.1 - 1.8 7.6 6.9 3.1 6.8 6.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CDC27 PF09507.10 OAJ09802.1 - 2.3 7.5 10.4 3.8 6.8 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2_4 PF13894.6 OAJ09803.1 - 0.0042 17.8 8.9 2.5 9.2 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAJ09803.1 - 0.006 16.8 7.9 0.74 9.9 0.0 3.3 2 1 1 3 3 3 2 Aberrant zinc-finger FOXP-CC PF16159.5 OAJ09803.1 - 0.013 16.1 0.2 0.079 13.6 0.0 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 OAJ09803.1 - 0.1 13.1 10.5 3 8.5 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type CPCFC PF17223.3 OAJ09803.1 - 0.2 11.5 1.8 0.38 10.5 1.8 1.5 1 0 0 1 1 1 0 Cuticle protein CPCFC SSP160 PF06933.11 OAJ09803.1 - 0.2 9.8 4.5 0.24 9.6 4.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_S3Ae PF01015.18 OAJ09810.1 - 3.4e-89 297.8 0.4 3.9e-89 297.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 OAJ09810.1 - 0.16 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SET PF00856.28 OAJ09811.1 - 5.9e-06 26.8 0.2 0.0028 18.1 0.0 2.5 2 1 1 3 3 3 2 SET domain SAF PF08666.12 OAJ09811.1 - 0.12 13.1 0.0 4.3 8.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain Cation_ATPase_C PF00689.21 OAJ09815.1 - 5.3e-36 124.0 2.1 7.8e-36 123.5 2.1 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ09815.1 - 2.9e-19 70.2 1.2 1.6e-09 38.4 0.3 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ09815.1 - 1.7e-14 53.6 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) An_peroxidase PF03098.15 OAJ09816.1 - 2.6e-39 135.2 0.1 1.1e-20 73.8 0.0 3.9 1 1 2 3 3 3 3 Animal haem peroxidase Peptidase_M15_4 PF13539.6 OAJ09823.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase OrfB_Zn_ribbon PF07282.11 OAJ09824.1 - 0.00016 21.5 0.6 0.017 15.0 0.1 2.6 2 0 0 2 2 2 2 Putative transposase DNA-binding domain HEAT PF02985.22 OAJ09830.1 - 6.3e-25 85.1 10.9 0.00031 20.8 0.0 11.3 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.6 OAJ09830.1 - 7.6e-16 58.2 15.2 8.7e-10 38.9 0.1 8.3 9 0 0 9 9 8 2 HEAT-like repeat HEAT_2 PF13646.6 OAJ09830.1 - 9.6e-13 48.3 9.3 0.036 14.4 0.0 6.5 2 2 4 6 6 6 5 HEAT repeats IBN_N PF03810.19 OAJ09830.1 - 4.3e-10 39.4 1.8 8.7e-07 28.8 0.2 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 OAJ09830.1 - 0.00022 21.1 11.1 0.0089 16.0 0.1 5.4 6 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 OAJ09830.1 - 0.00066 19.5 0.7 3.4 7.4 0.0 3.8 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) Vac14_Fab1_bd PF12755.7 OAJ09830.1 - 0.00079 20.0 0.1 0.58 10.8 0.1 4.7 5 1 2 7 7 6 2 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 OAJ09830.1 - 0.0017 18.0 0.2 0.057 13.0 0.5 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.8 OAJ09830.1 - 0.005 16.8 0.4 6 6.8 0.0 4.3 2 1 2 5 5 5 1 Domain of unknown function (DUF3385) Xpo1 PF08389.12 OAJ09830.1 - 0.0068 16.5 0.5 0.21 11.6 0.1 3.2 2 1 1 3 3 3 1 Exportin 1-like protein CLASP_N PF12348.8 OAJ09830.1 - 0.1 12.2 0.3 3.7 7.0 0.0 3.3 3 1 0 4 4 4 0 CLASP N terminal Cnd3 PF12719.7 OAJ09830.1 - 0.11 11.7 0.9 3.5 6.7 0.3 3.2 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Pex14_N PF04695.13 OAJ09831.1 - 3.6e-26 92.7 0.0 3.6e-26 92.7 0.0 3.8 3 1 0 4 4 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NPV_P10 PF05531.12 OAJ09831.1 - 0.00036 20.9 5.7 0.033 14.6 0.4 3.0 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 OAJ09831.1 - 0.00044 20.3 16.4 0.0014 18.7 2.6 2.3 2 1 1 3 3 2 2 Laminin Domain II Atg14 PF10186.9 OAJ09831.1 - 0.0019 17.3 2.7 0.0033 16.6 2.7 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAJ09831.1 - 0.003 16.5 9.9 0.0046 15.9 9.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 OAJ09831.1 - 0.0041 17.6 3.8 0.0068 16.9 3.8 1.3 1 0 0 1 1 1 1 Fez1 DUF885 PF05960.11 OAJ09831.1 - 0.0046 16.7 1.7 0.006 16.3 1.7 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF4795 PF16043.5 OAJ09831.1 - 0.0056 16.3 5.2 0.0088 15.7 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Golgin_A5 PF09787.9 OAJ09831.1 - 0.0093 15.5 8.0 0.014 14.8 8.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 IFT57 PF10498.9 OAJ09831.1 - 0.015 14.3 4.8 0.013 14.5 3.1 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5314 PF17241.2 OAJ09831.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) DLP_helical PF18709.1 OAJ09831.1 - 0.024 13.9 4.5 0.035 13.3 4.5 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain Baculo_PEP_C PF04513.12 OAJ09831.1 - 0.025 14.6 0.7 0.09 12.8 0.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RRP36 PF06102.12 OAJ09831.1 - 0.027 14.4 6.3 0.046 13.7 6.3 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 PI3K_P85_iSH2 PF16454.5 OAJ09831.1 - 0.029 14.0 3.9 0.045 13.3 3.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4835 PF16119.5 OAJ09831.1 - 0.033 13.3 1.0 0.049 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) DUF2968 PF11180.8 OAJ09831.1 - 0.034 13.8 10.4 0.071 12.7 10.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) BshC PF10079.9 OAJ09831.1 - 0.036 12.8 3.6 0.049 12.4 3.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PilJ PF13675.6 OAJ09831.1 - 0.043 13.8 5.8 0.17 11.9 4.0 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prominin PF05478.11 OAJ09831.1 - 0.075 11.0 1.0 0.1 10.5 1.0 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 OAJ09831.1 - 0.087 10.3 9.7 0.11 9.9 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Syntaxin PF00804.25 OAJ09831.1 - 0.094 12.4 5.5 0.19 11.4 5.4 1.5 1 1 0 1 1 1 0 Syntaxin zf-C4H2 PF10146.9 OAJ09831.1 - 0.11 12.8 7.7 0.13 12.6 6.5 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein Mt_ATP-synt_D PF05873.12 OAJ09831.1 - 0.16 11.8 4.0 1.2 9.0 4.0 2.0 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF948 PF06103.11 OAJ09831.1 - 0.16 12.2 9.4 2 8.7 0.7 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CEP63 PF17045.5 OAJ09831.1 - 0.17 11.8 7.7 0.33 10.8 7.6 1.5 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa FlgN PF05130.12 OAJ09831.1 - 0.21 12.1 10.7 0.34 11.4 10.7 1.2 1 0 0 1 1 1 0 FlgN protein DUF1664 PF07889.12 OAJ09831.1 - 0.22 11.6 10.4 0.25 11.4 0.8 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 OAJ09831.1 - 0.31 10.3 3.7 0.46 9.7 3.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Osmo_CC PF08946.10 OAJ09831.1 - 0.32 11.3 7.1 2.1 8.7 3.4 2.6 1 1 1 2 2 2 0 Osmosensory transporter coiled coil AAA_13 PF13166.6 OAJ09831.1 - 0.34 9.5 4.4 0.48 9.0 4.4 1.1 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 OAJ09831.1 - 0.38 9.3 3.5 0.56 8.7 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A EzrA PF06160.12 OAJ09831.1 - 0.39 8.8 7.6 1.4 7.0 7.6 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA CHIP_TPR_N PF18391.1 OAJ09831.1 - 0.41 11.4 5.8 0.46 11.3 3.6 2.1 1 1 1 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain BST2 PF16716.5 OAJ09831.1 - 0.49 11.0 8.1 1.2 9.8 3.1 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 ISG65-75 PF11727.8 OAJ09831.1 - 0.5 9.5 6.0 0.88 8.7 6.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.10 OAJ09831.1 - 0.58 10.3 3.5 1 9.5 0.8 2.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TipAS PF07739.13 OAJ09831.1 - 0.64 10.6 6.8 0.55 10.8 3.4 2.2 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain APG6_N PF17675.1 OAJ09831.1 - 0.87 10.1 17.3 0.87 10.1 10.6 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 OAJ09831.1 - 1.1 9.4 8.2 19 5.5 3.7 2.9 2 1 1 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 OAJ09831.1 - 1.2 9.6 10.5 6.2 7.2 2.8 3.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 OAJ09831.1 - 1.2 9.2 6.6 0.93 9.6 2.3 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.9 OAJ09831.1 - 1.2 9.8 4.4 2.6 8.8 4.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Cdh1_DBD_1 PF18196.1 OAJ09831.1 - 1.3 9.4 5.8 1.6 9.1 4.8 1.6 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 YabA PF06156.13 OAJ09831.1 - 1.7 9.4 5.6 17 6.1 1.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FTA4 PF13093.6 OAJ09831.1 - 1.7 8.5 9.2 4 7.3 8.0 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.9 OAJ09831.1 - 1.8 8.9 6.9 1.5 9.2 1.5 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 OAJ09831.1 - 1.8 7.8 11.2 3.5 6.9 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 OAJ09831.1 - 2 9.2 4.3 7.7 7.3 4.3 1.9 1 1 0 1 1 1 0 Occludin homology domain FUSC PF04632.12 OAJ09831.1 - 2.1 6.8 7.8 0.66 8.4 0.6 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 OAJ09831.1 - 2.1 8.4 12.6 34 4.5 12.4 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 OAJ09831.1 - 2.3 8.3 9.2 0.62 10.1 4.7 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 OAJ09831.1 - 2.3 8.7 8.2 0.61 10.6 2.5 2.2 1 1 1 2 2 2 0 Spectrin repeat CdvA PF18822.1 OAJ09831.1 - 2.4 8.0 9.3 1.2 9.0 5.5 2.0 1 1 1 2 2 2 0 CdvA-like coiled-coil domain UPF0242 PF06785.11 OAJ09831.1 - 3.1 7.8 9.7 4.9 7.2 9.2 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Serglycin PF04360.12 OAJ09831.1 - 3.8 7.5 12.0 0.05 13.6 4.6 1.6 2 0 0 2 2 1 0 Serglycin HIP1_clath_bdg PF16515.5 OAJ09831.1 - 5.5 7.7 12.2 31 5.2 11.9 2.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 OAJ09831.1 - 5.6 7.3 15.7 5.8 7.3 10.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin_2 PF01920.20 OAJ09831.1 - 7.4 6.6 10.5 12 6.0 5.6 2.9 1 1 2 3 3 3 0 Prefoldin subunit HALZ PF02183.18 OAJ09831.1 - 7.8 6.8 8.4 15 5.9 0.1 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper V-SNARE PF05008.15 OAJ09831.1 - 8 6.9 9.4 24 5.4 7.4 2.3 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Bax1-I PF01027.20 OAJ09837.1 - 2.4e-36 125.5 7.4 4.3e-36 124.7 7.4 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CitT PF12431.8 OAJ09838.1 - 0.00011 22.5 0.6 3 8.3 0.0 4.4 3 0 0 3 3 3 2 Transcriptional regulator AAA_2 PF07724.14 OAJ09845.1 - 7.3e-46 156.4 0.0 6.8e-44 150.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ09845.1 - 4.7e-30 103.6 2.3 4.7e-30 103.6 2.3 3.8 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 OAJ09845.1 - 2.9e-23 82.8 0.1 4.7e-12 46.5 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAJ09845.1 - 6.3e-22 77.4 0.1 2.7e-21 75.4 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 OAJ09845.1 - 7.3e-14 51.9 0.0 1.3e-07 31.7 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ09845.1 - 9.9e-12 45.6 11.7 4e-07 30.6 0.1 5.6 4 2 1 6 6 6 2 AAA ATPase domain Clp_N PF02861.20 OAJ09845.1 - 1.7e-11 44.1 2.8 1e-05 25.5 0.6 3.8 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 OAJ09845.1 - 8.9e-09 35.7 3.7 0.0095 16.2 0.0 4.9 3 2 1 4 4 3 2 AAA domain IstB_IS21 PF01695.17 OAJ09845.1 - 1.5e-07 31.4 0.1 0.03 14.0 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 OAJ09845.1 - 3.9e-06 26.7 0.0 0.0029 17.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 OAJ09845.1 - 9.8e-06 25.8 0.3 0.038 14.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAJ09845.1 - 2e-05 25.1 0.3 0.088 13.3 0.0 3.3 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 OAJ09845.1 - 3.4e-05 23.3 0.0 0.35 10.2 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 OAJ09845.1 - 5.9e-05 22.3 0.0 0.4 9.8 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 OAJ09845.1 - 6.6e-05 22.5 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ09845.1 - 7.9e-05 23.0 0.0 0.27 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 OAJ09845.1 - 0.0001 22.1 0.0 0.14 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OAJ09845.1 - 0.00023 21.1 6.4 0.22 11.4 0.0 5.0 5 1 0 6 6 5 1 ATPase domain predominantly from Archaea TsaE PF02367.17 OAJ09845.1 - 0.00033 20.7 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 OAJ09845.1 - 0.00033 20.6 0.0 0.74 9.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 OAJ09845.1 - 0.00036 20.5 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 OAJ09845.1 - 0.00037 20.7 0.0 1.3 9.3 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 OAJ09845.1 - 0.0005 19.4 0.1 0.38 9.9 0.1 2.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_28 PF13521.6 OAJ09845.1 - 0.00051 20.3 1.6 2.5 8.3 0.0 3.8 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 OAJ09845.1 - 0.00067 19.4 0.1 0.49 10.1 0.0 3.4 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ09845.1 - 0.00084 18.8 0.0 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ09845.1 - 0.0025 18.1 0.0 0.45 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 OAJ09845.1 - 0.0033 17.3 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 OAJ09845.1 - 0.004 16.5 0.0 1.1 8.5 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 OAJ09845.1 - 0.0041 17.6 0.4 2 9.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.6 OAJ09845.1 - 0.006 16.3 0.0 2.4 7.9 0.0 3.2 3 1 0 3 3 2 1 AAA domain SRP54 PF00448.22 OAJ09845.1 - 0.0065 16.1 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 OAJ09845.1 - 0.0083 15.9 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ09845.1 - 0.011 15.6 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 OAJ09845.1 - 0.016 15.0 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cob_adeno_trans PF01923.18 OAJ09845.1 - 0.02 15.1 1.4 0.062 13.4 1.4 1.9 1 0 0 1 1 1 0 Cobalamin adenosyltransferase AAA_14 PF13173.6 OAJ09845.1 - 0.033 14.2 0.1 1.2 9.2 0.0 2.9 3 1 0 3 3 2 0 AAA domain AAA_23 PF13476.6 OAJ09845.1 - 0.037 14.5 16.5 0.21 12.1 0.0 4.0 3 2 0 3 3 2 0 AAA domain AAA_3 PF07726.11 OAJ09845.1 - 0.08 12.8 0.0 20 5.1 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_8 PF12780.7 OAJ09845.1 - 0.1 11.9 0.1 4.9 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 ResIII PF04851.15 OAJ09845.1 - 0.13 12.2 0.0 91 3.0 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF3443 PF11925.8 OAJ09845.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) AAA_17 PF13207.6 OAJ09845.1 - 0.42 11.0 3.9 35 4.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF4407 PF14362.6 OAJ09845.1 - 0.45 9.8 7.3 1.1 8.6 7.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PV-1 PF06637.11 OAJ09845.1 - 0.94 8.2 8.7 1.6 7.5 8.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CorA PF01544.18 OAJ09845.1 - 3.7 6.8 6.5 8.6 5.6 6.5 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_GP20 PF06810.11 OAJ09845.1 - 5.5 6.8 17.8 0.46 10.3 10.5 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 OAJ09849.1 - 0 1029.7 0.0 0 1029.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spc7 PF08317.11 OAJ09849.1 - 0.053 12.4 3.5 0.097 11.5 3.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 OAJ09849.1 - 0.057 13.9 0.7 0.16 12.4 0.7 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Exonuc_VII_L PF02601.15 OAJ09849.1 - 0.078 12.5 1.7 0.14 11.7 1.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TSNAXIP1_N PF15739.5 OAJ09849.1 - 0.12 12.8 0.7 22 5.4 0.6 2.5 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus GAS PF13851.6 OAJ09849.1 - 0.19 11.1 4.6 0.94 8.8 2.3 2.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 OAJ09849.1 - 0.65 10.0 5.7 0.11 12.4 0.5 2.3 3 0 0 3 3 3 0 Prefoldin subunit Gp58 PF07902.11 OAJ09849.1 - 1 7.6 5.2 1.5 7.0 5.2 1.1 1 0 0 1 1 1 0 gp58-like protein ABC_tran_CTD PF16326.5 OAJ09849.1 - 1.2 9.4 4.2 4.7 7.5 4.3 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain FTA4 PF13093.6 OAJ09849.1 - 1.4 8.8 8.3 15 5.4 8.3 2.2 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fib_alpha PF08702.10 OAJ09849.1 - 8.7 6.5 6.2 18 5.5 4.4 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Helicase_C PF00271.31 OAJ09850.1 - 4.6e-28 97.8 0.0 6.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_2 PF07727.14 OAJ09858.1 - 9.4e-62 208.8 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 OAJ09858.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 rve PF00665.26 OAJ09859.1 - 8e-23 80.9 0.1 1.6e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ09859.1 - 1e-06 28.5 0.0 7.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ09859.1 - 0.0016 18.2 0.1 0.0073 16.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain TcpQ PF10671.9 OAJ09859.1 - 0.13 12.4 1.8 3.6 7.8 0.3 2.4 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Retrotrans_gag PF03732.17 OAJ09860.1 - 3.2e-07 30.5 0.1 9.4e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 OAJ09860.1 - 9.9e-07 28.5 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 OAJ09860.1 - 0.1 12.4 1.9 0.2 11.4 1.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger RT_RNaseH PF17917.1 OAJ09863.1 - 4.7e-15 55.8 0.0 1.5e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ09863.1 - 6.2e-15 55.1 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ09863.1 - 1.8e-08 34.2 0.0 4.3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ09863.1 - 4.4e-06 27.2 0.0 1.7e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 OAJ09863.1 - 2.6e-05 24.0 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09863.1 - 6.3e-05 23.5 0.0 0.00018 22.0 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 OAJ09863.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease PSI_integrin PF17205.3 OAJ09863.1 - 0.061 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Integrin plexin domain RVP PF00077.20 OAJ09863.1 - 0.15 12.4 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1707 PF08044.11 OAJ09863.1 - 0.21 11.7 1.5 0.43 10.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Rad60-SLD PF11976.8 OAJ09864.1 - 0.0047 16.7 0.3 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Transposase_21 PF02992.14 OAJ09868.1 - 1.4e-08 34.3 0.0 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ09868.1 - 0.003 17.2 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) GAPT PF11770.8 OAJ09878.1 - 0.018 14.9 0.1 0.097 12.5 0.0 2.1 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) DUF5527 PF17665.1 OAJ09878.1 - 0.038 13.5 0.2 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Roughex PF06020.11 OAJ09878.1 - 2 7.5 5.0 3.6 6.6 5.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein NAD_binding_8 PF13450.6 OAJ09884.1 - 3.4e-09 36.8 0.1 6e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAJ09884.1 - 8e-09 35.3 0.0 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 OAJ09884.1 - 0.00014 21.2 0.0 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ09884.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ09884.1 - 0.016 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 OAJ09884.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ09884.1 - 0.024 13.9 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ09884.1 - 0.026 13.8 0.1 0.05 12.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 OAJ09884.1 - 0.03 13.0 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAJ09884.1 - 0.065 12.3 0.3 0.1 11.6 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 OAJ09884.1 - 0.17 10.9 0.2 0.28 10.2 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 OAJ09884.1 - 0.24 11.4 0.0 0.24 11.4 0.0 2.2 3 0 0 3 3 2 0 FAD-NAD(P)-binding DSHCT PF08148.12 OAJ09885.1 - 2e-21 76.4 0.4 2.2e-21 76.2 0.4 1.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain ArsC PF03960.15 OAJ09885.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 ArsC family Uds1 PF15456.6 OAJ09887.1 - 0.033 14.3 1.0 0.078 13.1 1.0 1.6 1 0 0 1 1 1 0 Up-regulated During Septation eIF-3c_N PF05470.12 OAJ09887.1 - 0.068 11.5 0.3 0.094 11.0 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Seryl_tRNA_N PF02403.22 OAJ09887.1 - 0.43 10.8 4.0 1.1 9.5 1.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.6 OAJ09887.1 - 0.63 9.4 8.3 11 5.3 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding LMP PF04778.12 OAJ09887.1 - 1.2 9.1 6.8 0.25 11.3 2.0 2.0 2 0 0 2 2 2 0 LMP repeated region EMP70 PF02990.16 OAJ09895.1 - 1.1e-182 608.3 0.3 1.4e-182 608.0 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NPBW PF15180.6 OAJ09895.1 - 0.085 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Neuropeptides B and W Inhibitor_Mig-6 PF11555.8 OAJ09895.1 - 0.43 10.7 2.2 21 5.3 0.4 2.7 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 Med3 PF11593.8 OAJ09896.1 - 0.68 9.1 8.3 2.1 7.5 8.2 1.8 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 OAJ09896.1 - 2.9 8.0 11.5 8.1 6.6 1.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RVT_1 PF00078.27 OAJ09911.1 - 4.5e-26 91.7 0.0 6.5e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zip PF02535.22 OAJ09919.1 - 0.023 13.9 0.1 0.029 13.6 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 OAJ09919.1 - 0.063 12.1 1.6 0.069 12.0 1.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 OAJ09919.1 - 0.099 11.4 0.3 0.11 11.3 0.3 1.1 1 0 0 1 1 1 0 Presenilin Podoplanin PF05808.11 OAJ09919.1 - 0.18 11.9 0.0 0.23 11.5 0.0 1.1 1 0 0 1 1 1 0 Podoplanin DUF755 PF05501.11 OAJ09919.1 - 0.27 11.5 13.0 0.42 10.9 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SWIRM-assoc_2 PF16496.5 OAJ09919.1 - 0.27 10.1 6.1 0.33 9.8 6.1 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal SRP-alpha_N PF04086.13 OAJ09919.1 - 0.7 9.8 9.7 0.84 9.5 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 OAJ09919.1 - 1.6 6.9 8.6 1.8 6.8 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 OAJ09919.1 - 1.7 8.4 4.8 2.1 8.1 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 OAJ09919.1 - 2 8.3 9.7 2.6 7.9 9.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4551 PF15087.6 OAJ09919.1 - 2.9 6.6 5.2 3.3 6.4 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RVT_1 PF00078.27 OAJ09926.1 - 2e-22 79.8 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ09926.1 - 1.2e-18 67.0 0.0 1.2e-11 44.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ09926.1 - 1.5e-15 57.1 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ09926.1 - 8e-13 48.6 0.0 5.2e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ09926.1 - 2.6e-11 43.8 0.1 6e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ09926.1 - 1.8e-05 25.3 0.1 8.5e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ09926.1 - 0.0016 18.9 0.0 0.0063 17.0 0.0 2.0 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease SDA1 PF05285.12 OAJ09936.1 - 8.4e-05 22.2 26.2 8.4e-05 22.2 26.2 2.5 2 0 0 2 2 2 1 SDA1 GAS PF13851.6 OAJ09936.1 - 0.85 8.9 24.1 2.3 7.5 14.4 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 OAJ09936.1 - 1.2 9.2 9.8 0.085 12.9 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Piwi PF02171.17 OAJ09943.1 - 2.9e-74 250.0 0.0 3.9e-74 249.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 OAJ09943.1 - 3.8e-10 40.0 0.8 1.1e-09 38.5 0.2 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 OAJ09943.1 - 5.7e-09 35.9 0.0 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 OAJ09943.1 - 8.9e-09 35.5 0.0 2.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Alpha-amyl_C2 PF07821.12 OAJ09943.1 - 0.15 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain Mannosyl_trans PF05007.13 OAJ09944.1 - 6.6e-52 176.9 18.7 2.1e-47 162.2 15.7 3.5 2 1 0 2 2 2 2 Mannosyltransferase (PIG-M) F-box-like PF12937.7 OAJ09949.1 - 0.0002 21.2 0.5 0.00072 19.4 0.5 2.0 1 0 0 1 1 1 1 F-box-like Thioredoxin PF00085.20 OAJ09950.1 - 1e-09 38.3 0.0 1.2e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 OAJ09950.1 - 0.00047 19.6 0.0 0.00047 19.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 OAJ09950.1 - 0.034 14.4 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 OAJ09950.1 - 0.09 13.2 0.0 0.1 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain TatD_DNase PF01026.21 OAJ09951.1 - 1.3e-19 70.6 0.3 2.4e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 TatD related DNase DUF913 PF06025.12 OAJ09951.1 - 0.071 12.1 4.1 0.92 8.4 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SHQ1 PF04925.15 OAJ09951.1 - 0.21 11.1 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Nucleocapsid-N PF11030.8 OAJ09961.1 - 0.034 14.1 4.1 0.057 13.4 4.1 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N IF4E PF01652.18 OAJ09962.1 - 3e-46 157.1 0.3 9.6e-46 155.5 0.3 1.7 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E IHABP4_N PF16174.5 OAJ09962.1 - 3.3 8.3 9.0 38 4.9 5.4 2.8 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal SUIM_assoc PF16619.5 OAJ09965.1 - 0.28 11.3 4.6 1.5 9.0 4.6 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Mitofilin PF09731.9 OAJ09966.1 - 7e-06 25.2 1.8 7.3e-06 25.1 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein NUDIX_4 PF14815.6 OAJ09967.1 - 1.7e-15 57.0 0.0 6.3e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 OAJ09967.1 - 2.8e-14 53.5 0.0 6.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ09967.1 - 9.2e-05 22.1 0.1 0.00023 20.9 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Bul1_C PF04426.12 OAJ09967.1 - 0.014 14.9 2.1 0.026 13.9 2.1 1.4 1 0 0 1 1 1 0 Bul1 C terminus PG_binding_2 PF08823.11 OAJ09967.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Pannexin_like PF12534.8 OAJ09967.1 - 5.5 6.0 9.0 9.5 5.2 9.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 CHAD PF05235.14 OAJ09972.1 - 0.024 14.6 0.0 7.9 6.4 0.0 2.7 2 0 0 2 2 2 0 CHAD domain Vir_act_alpha_C PF10400.9 OAJ09972.1 - 1.6 9.4 4.0 3.2 8.5 1.1 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term SNase PF00565.17 OAJ09973.1 - 5.6e-21 75.0 2.4 2.4e-19 69.8 1.0 2.7 2 1 0 2 2 2 1 Staphylococcal nuclease homologue LSM14 PF12701.7 OAJ09980.1 - 8.4e-26 89.9 0.0 1.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 OAJ09980.1 - 1.2e-06 29.4 3.6 1.3e-06 29.2 0.0 2.7 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 OAJ09980.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain CDC37_N PF03234.14 OAJ09981.1 - 2.4e-35 122.3 2.3 4e-35 121.5 0.0 2.4 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 OAJ09981.1 - 3.8e-19 68.7 0.0 9.5e-19 67.5 0.0 1.6 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 OAJ09981.1 - 3.4e-15 56.0 0.3 1.1e-14 54.3 0.1 2.0 2 0 0 2 2 2 1 Cdc37 C terminal domain CENP-L PF13092.6 OAJ09981.1 - 0.07 13.3 0.4 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 DFRP_C PF16543.5 OAJ09981.1 - 0.75 10.3 4.4 1.1 9.8 0.2 2.6 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Ldh_1_C PF02866.18 OAJ09986.1 - 8.8e-24 84.3 0.0 1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Mlf1IP PF10248.9 OAJ09993.1 - 0.079 12.9 2.8 0.19 11.7 2.8 1.7 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Transposase_21 PF02992.14 OAJ09997.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Transposase family tnp2 InaF-motif PF15018.6 OAJ09999.1 - 0.26 11.2 1.3 0.28 11.1 0.2 1.5 2 0 0 2 2 2 0 TRP-interacting helix TFIIA PF03153.13 OAJ09999.1 - 0.5 10.3 4.0 0.63 10.0 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP_N PF14636.6 OAJ09999.1 - 0.72 10.8 4.3 1 10.3 4.3 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus zf-CCHC PF00098.23 OAJ10006.1 - 0.00016 21.6 1.5 0.00034 20.6 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ10006.1 - 0.00017 21.3 0.0 0.00047 19.8 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF3350 PF11830.8 OAJ10006.1 - 0.13 12.5 0.1 0.48 10.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) RVT_2 PF07727.14 OAJ10007.1 - 1.6e-70 237.5 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.27 OAJ10015.1 - 2.2e-50 170.9 0.0 3.7e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 OAJ10015.1 - 2.9e-38 130.3 0.1 5.5e-38 129.4 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 OAJ10015.1 - 1.3e-12 47.5 0.0 3.8e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ10015.1 - 8.5e-07 29.3 0.2 1.8e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ10015.1 - 8.5e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 OAJ10015.1 - 0.00034 20.6 0.0 0.00088 19.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 OAJ10015.1 - 0.0037 16.7 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 OAJ10015.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain NARP1 PF12569.8 OAJ10028.1 - 2.4 7.0 8.1 3.4 6.5 8.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Polysacc_deac_1 PF01522.21 OAJ10042.1 - 2.7e-21 75.8 0.0 5.3e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 OAJ10042.1 - 0.0052 16.0 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 OAJ10042.1 - 0.11 12.1 0.2 0.24 11.0 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4263 PF14082.6 OAJ10042.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) zf-CCHC PF00098.23 OAJ10043.1 - 0.001 19.1 4.5 0.0021 18.0 4.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ10043.1 - 0.068 13.1 0.4 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle TTRAP PF14203.6 OAJ10043.1 - 0.14 12.2 0.2 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein Acyl-thio_N PF12590.8 OAJ10043.1 - 0.77 10.3 3.2 3.1 8.4 1.8 2.5 2 0 0 2 2 2 0 Acyl-ATP thioesterase TPR_14 PF13428.6 OAJ10057.1 - 2.3e-06 28.0 22.0 0.05 14.5 0.1 5.7 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ10057.1 - 6.1e-06 26.0 0.9 0.15 12.2 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ10057.1 - 6.1e-05 22.7 0.1 0.034 14.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ10057.1 - 0.00032 20.9 10.9 0.22 11.8 0.5 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ10057.1 - 0.001 19.1 0.3 1.7 9.1 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ10057.1 - 0.033 14.2 1.1 0.44 10.7 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ10057.1 - 0.04 14.6 17.0 6.1 7.8 0.1 5.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ10057.1 - 0.052 13.4 3.1 6.3 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Cation_efflux PF01545.21 OAJ10057.1 - 0.079 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Cation efflux family TFIIA PF03153.13 OAJ10065.1 - 0.032 14.2 10.8 0.035 14.1 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 OAJ10065.1 - 6.7 4.9 13.0 8.3 4.5 13.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4207 PF13904.6 OAJ10066.1 - 0.014 15.1 5.4 0.019 14.7 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Dimer_Tnp_hAT PF05699.14 OAJ10067.1 - 5.6e-25 87.0 0.1 8.6e-25 86.3 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region WD40 PF00400.32 OAJ10075.1 - 1.9e-06 28.5 13.9 0.0058 17.5 0.1 5.9 5 1 0 5 5 5 2 WD domain, G-beta repeat RWD PF05773.22 OAJ10075.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain NDC10_II PF16787.5 OAJ10083.1 - 9.8e-39 133.3 0.0 1.3e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 zf-RING_2 PF13639.6 OAJ10091.1 - 2.5e-07 30.9 1.5 9.1e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ10091.1 - 2.7e-07 30.5 0.3 2.7e-07 30.5 0.3 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 OAJ10091.1 - 1.9e-06 27.5 2.1 4e-06 26.5 2.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAJ10091.1 - 3.2e-06 27.0 1.3 1.3e-05 25.1 0.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 OAJ10091.1 - 9.3e-05 22.2 0.1 9.3e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ10091.1 - 0.0019 18.0 0.4 0.0019 18.0 0.4 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ10091.1 - 0.014 15.7 2.7 0.015 15.6 0.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain DUF4407 PF14362.6 OAJ10091.1 - 1.7 7.9 20.0 3.3 7.0 20.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JHY PF15261.6 OAJ10091.1 - 2.8 8.7 25.8 2.4 8.9 6.9 2.8 2 0 0 2 2 2 0 Jhy protein Prok-RING_4 PF14447.6 OAJ10091.1 - 4.7 7.2 6.6 1.5 8.7 1.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF87 PF01935.17 OAJ10091.1 - 9.2 6.3 8.0 18 5.3 8.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain zf-C3HC4_3 PF13920.6 OAJ10091.1 - 9.3 6.2 7.1 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.11 OAJ10096.1 - 0.069 13.1 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Prp19/Pso4-like HEAT_EZ PF13513.6 OAJ10097.1 - 1.3e-09 38.4 14.6 0.028 14.9 0.3 6.4 3 1 3 6 6 6 4 HEAT-like repeat HEAT PF02985.22 OAJ10097.1 - 2.7e-05 24.1 9.4 21 5.7 0.0 8.0 8 0 0 8 8 8 0 HEAT repeat RIX1 PF08167.12 OAJ10097.1 - 0.00023 21.0 1.1 0.51 10.1 0.1 3.2 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 OAJ10097.1 - 0.00032 21.0 16.8 0.022 15.1 3.0 5.4 4 1 2 6 6 6 3 HEAT repeats Phage_TAC_12 PF12363.8 OAJ10097.1 - 0.0015 18.9 0.0 0.058 13.8 0.0 3.1 2 1 1 3 3 3 1 Phage tail assembly chaperone protein, TAC ParcG PF10274.9 OAJ10097.1 - 0.0033 17.6 0.0 0.047 13.8 0.0 2.6 3 0 0 3 3 3 1 Parkin co-regulated protein Ecm29 PF13001.7 OAJ10097.1 - 0.0088 14.8 0.0 0.033 12.9 0.0 1.9 2 1 0 2 2 2 1 Proteasome stabiliser DUF3437 PF11919.8 OAJ10097.1 - 0.094 12.6 0.7 3.6 7.6 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) tRNA_synt_2f PF02092.17 OAJ10097.1 - 0.13 11.1 0.7 0.35 9.7 0.1 1.9 2 0 0 2 2 2 0 Glycyl-tRNA synthetase beta subunit DUF3385 PF11865.8 OAJ10097.1 - 0.16 11.9 0.0 3.1 7.7 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3385) Apolipoprotein PF01442.18 OAJ10097.1 - 0.37 10.7 3.3 2.4 8.0 1.3 3.2 2 2 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3535 PF12054.8 OAJ10097.1 - 0.77 8.9 2.8 1 8.6 0.9 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF3535) HEAT_PBS PF03130.16 OAJ10097.1 - 4.3 8.3 11.3 1.3 9.9 0.3 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat KfrA_N PF11740.8 OAJ10097.1 - 7.8 7.2 16.6 1.2 9.8 2.1 4.0 3 1 1 4 4 3 0 Plasmid replication region DNA-binding N-term DDE_Tnp_4 PF13359.6 OAJ10104.1 - 1.1e-10 41.5 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ10104.1 - 0.013 15.1 0.2 0.025 14.2 0.2 1.5 1 1 0 1 1 1 0 Transposase DDE domain Plant_tran PF04827.14 OAJ10104.1 - 0.022 14.3 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_1_2 PF13586.6 OAJ10104.1 - 0.033 14.6 0.1 0.075 13.4 0.1 1.6 2 0 0 2 2 2 0 Transposase DDE domain Transposase_21 PF02992.14 OAJ10111.1 - 2.9e-05 23.4 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 KIF1B PF12423.8 OAJ10111.1 - 0.023 15.1 0.5 0.084 13.3 0.5 2.0 1 0 0 1 1 1 0 Kinesin protein 1B CDC45 PF02724.14 OAJ10112.1 - 0.17 10.1 6.5 0.19 10.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 OAJ10112.1 - 0.23 10.4 3.9 0.23 10.4 3.0 1.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) PPP4R2 PF09184.11 OAJ10112.1 - 2 8.0 10.3 3.1 7.3 10.3 1.3 1 0 0 1 1 1 0 PPP4R2 RVT_1 PF00078.27 OAJ10121.1 - 2.2e-17 63.3 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 OAJ10130.1 - 1.3e-06 28.7 0.1 4.6e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ10130.1 - 0.00017 21.2 1.1 0.00052 19.6 1.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger UCR_6-4kD PF08997.10 OAJ10130.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein PGK PF00162.19 OAJ10137.1 - 1.9e-148 494.5 3.5 2.1e-148 494.3 3.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NTF2 PF02136.20 OAJ10138.1 - 9.6e-33 113.3 0.1 1.2e-32 113.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 OAJ10138.1 - 0.029 14.8 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) TFIIA PF03153.13 OAJ10139.1 - 7.6 6.4 30.8 2.9 7.8 21.7 2.2 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFIID_30kDa PF03540.13 OAJ10140.1 - 9.3e-25 86.3 0.0 1.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBS PF00571.28 OAJ10140.1 - 5.5e-05 23.5 0.0 0.0091 16.4 0.0 2.5 2 0 0 2 2 2 1 CBS domain Ribosomal_60s PF00428.19 OAJ10140.1 - 0.24 12.0 0.1 0.24 12.0 0.1 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein FoP_duplication PF13865.6 OAJ10140.1 - 2.9 8.5 12.2 0.1 13.2 2.8 2.6 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 GIT_SHD PF08518.11 OAJ10145.1 - 4.8e-24 83.7 8.2 1.4e-13 50.2 1.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ApoLp-III PF07464.11 OAJ10145.1 - 4.7e-06 26.8 10.0 1.4 9.0 0.5 4.6 4 0 0 4 4 4 3 Apolipophorin-III precursor (apoLp-III) GIT1_C PF12205.8 OAJ10145.1 - 0.0027 17.8 6.0 0.049 13.7 0.0 3.9 3 1 1 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF3584 PF12128.8 OAJ10145.1 - 0.89 7.0 26.2 0.07 10.6 21.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FKBP_C PF00254.28 OAJ10146.1 - 2.5e-34 117.5 0.2 3.8e-33 113.7 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Apolipoprotein PF01442.18 OAJ10146.1 - 1.9e-05 24.6 13.9 2.5e-05 24.2 13.9 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 OAJ10146.1 - 0.0023 18.0 8.7 0.0023 18.0 8.7 2.2 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Phasin_2 PF09361.10 OAJ10146.1 - 0.0023 18.2 16.9 0.0024 18.1 14.6 2.0 1 1 1 2 2 2 1 Phasin protein YtxH PF12732.7 OAJ10146.1 - 0.029 14.9 21.9 0.34 11.5 8.8 3.0 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 OAJ10146.1 - 0.099 13.3 15.8 0.44 11.2 5.5 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GGDEF PF00990.21 OAJ10146.1 - 0.49 10.1 2.9 0.8 9.4 2.9 1.4 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Borrelia_P83 PF05262.11 OAJ10146.1 - 1.6 7.2 17.9 2.2 6.7 17.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DivIVA PF05103.13 OAJ10146.1 - 2.4 8.3 21.3 5.8 7.0 7.2 2.2 1 1 1 2 2 2 0 DivIVA protein HisKA_3 PF07730.13 OAJ10146.1 - 2.9 8.5 5.6 3.7 8.1 1.2 2.9 1 1 1 2 2 2 0 Histidine kinase DUF1508 PF07411.12 OAJ10146.1 - 6.7 6.7 13.3 5.4 7.0 0.8 4.3 2 2 4 6 6 6 0 Domain of unknown function (DUF1508) HK97-gp10_like PF04883.12 OAJ10146.1 - 8.3 7.5 18.7 57 4.8 9.6 3.5 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Acyltransferase PF01553.21 OAJ10151.1 - 2.2e-24 85.6 0.0 3.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 OAJ10151.1 - 7.9e-08 32.3 0.3 2.9e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Cwf_Cwc_15 PF04889.12 OAJ10152.1 - 0.24 11.1 1.5 0.33 10.7 1.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CNDH2_M PF16869.5 OAJ10152.1 - 0.66 10.7 9.0 1.4 9.6 9.0 1.5 1 0 0 1 1 1 0 PF16858 Med13_C PF06333.12 OAJ10152.1 - 2.5 7.3 11.2 3.7 6.7 11.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Peptidase_M23 PF01551.22 OAJ10157.1 - 0.0003 20.9 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 RVT_1 PF00078.27 OAJ10164.1 - 4e-26 91.9 0.0 7.2e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ10164.1 - 3.4e-16 59.4 0.0 9.8e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10164.1 - 1.1e-15 57.4 0.1 4.5e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10164.1 - 3.1e-14 52.8 0.1 5.2e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10164.1 - 2e-10 40.9 0.0 4.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10164.1 - 0.00035 21.2 0.0 0.0025 18.4 0.0 2.3 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ10164.1 - 0.16 12.2 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger DUF1631 PF07793.11 OAJ10165.1 - 2.9 6.2 6.2 6.6 5.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) NDC10_II PF16787.5 OAJ10172.1 - 7.2e-34 117.3 0.0 1.1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Molybdopterin_N PF18364.1 OAJ10172.1 - 0.31 11.1 1.1 23 5.1 0.1 3.0 3 0 0 3 3 3 0 Molybdopterin oxidoreductase N-terminal domain SseC PF04888.12 OAJ10172.1 - 0.34 10.5 4.4 0.22 11.1 0.3 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Baculo_PEP_C PF04513.12 OAJ10172.1 - 0.98 9.5 4.2 0.39 10.8 1.4 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HTH_Tnp_1 PF01527.20 OAJ10173.1 - 0.0034 17.7 0.9 0.011 16.0 0.1 2.2 2 1 0 2 2 2 1 Transposase HTH_23 PF13384.6 OAJ10173.1 - 0.021 14.6 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 OAJ10173.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 OAJ10173.1 - 0.025 14.6 0.0 0.095 12.7 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Coatomer_WDAD PF04053.14 OAJ10177.1 - 2.2e-101 340.1 0.0 3.9e-69 233.8 0.0 2.0 1 1 1 2 2 2 2 Coatomer WD associated region DUF3437 PF11919.8 OAJ10178.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) RT_RNaseH_2 PF17919.1 OAJ10199.1 - 7e-31 106.2 0.0 1.7e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10199.1 - 1.9e-27 95.6 0.0 4.2e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10199.1 - 5e-21 75.2 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10199.1 - 9.5e-13 48.4 0.0 3.4e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10199.1 - 2.8e-09 36.9 0.8 6.7e-09 35.7 0.8 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ10199.1 - 0.022 14.5 0.0 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF2268 PF10026.9 OAJ10199.1 - 0.084 12.4 0.8 0.17 11.4 0.8 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PEPCK_ATP PF01293.20 OAJ10204.1 - 1.4e-214 713.1 0.0 1.6e-214 712.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 OAJ10204.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Histone PF00125.24 OAJ10211.1 - 1.6e-40 138.5 0.4 1.6e-40 138.5 0.4 3.2 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ10211.1 - 0.00081 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ10211.1 - 0.0021 18.2 0.1 0.0049 17.0 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DUF4413 PF14372.6 OAJ10211.1 - 0.051 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) F-box PF00646.33 OAJ10219.1 - 0.0027 17.5 0.0 0.0046 16.8 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ10219.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1845 PF08900.11 OAJ10219.1 - 0.1 12.3 0.2 0.16 11.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1845) DUF2797 PF10977.8 OAJ10219.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) ANAPC4_WD40 PF12894.7 OAJ10220.1 - 0.015 15.6 0.0 0.12 12.7 0.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 OAJ10220.1 - 0.099 11.9 0.6 6.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Vinculin PF01044.19 OAJ10221.1 - 0.14 10.3 0.2 0.2 9.8 0.2 1.1 1 0 0 1 1 1 0 Vinculin family zf-CCHC PF00098.23 OAJ10228.1 - 3.2e-05 23.8 1.8 8e-05 22.5 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ10228.1 - 0.0017 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 OAJ10228.1 - 0.027 14.3 0.9 0.057 13.2 0.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Herpes_capsid PF06112.11 OAJ10228.1 - 0.07 13.2 2.3 0.75 9.8 0.3 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein zf-CCHC_5 PF14787.6 OAJ10228.1 - 0.84 9.4 2.9 0.58 9.9 0.4 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 OAJ10228.1 - 3 7.6 3.9 1.1 9.1 1.2 1.6 2 0 0 2 2 2 0 Zinc knuckle RVT_2 PF07727.14 OAJ10229.1 - 2.7e-67 226.9 0.0 3.8e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10229.1 - 3.7e-15 56.1 0.1 2e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10229.1 - 1e-06 28.5 0.0 3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ10229.1 - 0.00018 21.2 0.4 0.016 15.0 0.0 2.9 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.27 OAJ10229.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb1_6 PF04992.14 OAJ10236.1 - 0.04 13.7 0.2 0.05 13.4 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 DUF5310 PF17237.2 OAJ10243.1 - 8.5e-19 67.2 5.7 1e-18 66.9 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Ribosomal_L15e PF00827.17 OAJ10244.1 - 2.4e-87 291.6 7.4 2.7e-87 291.4 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L5e PF17144.4 OAJ10245.1 - 3e-76 255.0 0.0 3e-76 255.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 OAJ10245.1 - 1.3e-33 115.8 5.2 1.3e-33 115.8 5.2 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 OAJ10245.1 - 0.035 14.5 0.2 0.035 14.5 0.2 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast MtrA PF04208.14 OAJ10245.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Phage_integrase PF00589.22 OAJ10254.1 - 1.7e-05 24.7 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Cyclin_N PF00134.23 OAJ10255.1 - 2.2e-13 50.1 0.0 3.6e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ10255.1 - 2.7e-09 37.6 1.0 4.1e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin Isochorismatase PF00857.20 OAJ10256.1 - 1.2e-32 113.5 0.3 1.6e-32 113.1 0.3 1.1 1 0 0 1 1 1 1 Isochorismatase family CMAS PF02353.20 OAJ10261.1 - 7.5e-56 189.4 0.0 1.8e-51 175.0 0.0 2.9 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ10261.1 - 9.2e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ10261.1 - 7.5e-10 39.3 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ10261.1 - 2.3e-08 34.0 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ10261.1 - 3.8e-08 33.3 0.0 9.5e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ10261.1 - 5.5e-05 23.8 0.0 0.0001 23.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 OAJ10261.1 - 0.0039 17.0 0.0 0.0059 16.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 OAJ10261.1 - 0.017 16.1 0.0 0.036 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 OAJ10261.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 OAJ10261.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 OAJ10261.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.9 OAJ10261.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 2 0 0 2 2 2 0 Lysine methyltransferase Stealth_CR2 PF11380.8 OAJ10262.1 - 5.7e-31 106.9 0.1 1e-30 106.0 0.1 1.4 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 PAT1 PF09770.9 OAJ10262.1 - 2.8e-14 52.4 0.2 5.6e-14 51.4 0.0 1.5 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Stealth_CR3 PF17102.5 OAJ10262.1 - 2.3e-09 37.0 2.0 2.5e-09 36.9 0.7 1.8 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR1 PF17101.5 OAJ10262.1 - 0.00015 21.4 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 SdpI PF13630.6 OAJ10262.1 - 0.11 12.7 0.5 0.23 11.6 0.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family PAT1 PF09770.9 OAJ10263.1 - 8.2e-10 37.6 0.0 1.9e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 OPT PF03169.15 OAJ10270.1 - 1.1e-89 301.8 27.9 1.2e-89 301.6 27.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3792 PF12670.7 OAJ10270.1 - 1.2 9.3 12.7 6.8 6.9 0.4 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) OPT PF03169.15 OAJ10271.1 - 1e-64 219.3 23.5 1.2e-64 219.1 23.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydantoinase_A PF01968.18 OAJ10275.1 - 2e-96 322.7 0.9 5.4e-95 318.0 0.7 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 OAJ10275.1 - 8.1e-60 201.6 0.9 1.4e-57 194.3 0.0 2.6 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region DUF3053 PF11254.8 OAJ10276.1 - 0.047 13.3 0.2 0.076 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) PAPA-1 PF04795.12 OAJ10282.1 - 3.5e-24 85.4 3.3 3.5e-24 85.4 3.3 3.5 3 3 0 3 3 3 1 PAPA-1-like conserved region Atg14 PF10186.9 OAJ10282.1 - 0.68 9.0 3.6 0.99 8.4 3.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 OAJ10283.1 - 1.1e-53 179.1 5.9 2e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PUMA PF15826.5 OAJ10283.1 - 0.013 15.7 0.6 0.025 14.8 0.6 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Dehydrin PF00257.19 OAJ10283.1 - 1.3 9.5 3.9 1.4 9.5 3.1 1.4 1 1 0 1 1 1 0 Dehydrin RVT_1 PF00078.27 OAJ10288.1 - 6.6e-11 42.1 0.0 9.9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ10288.1 - 1.3e-05 25.7 0.0 2.9e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10288.1 - 0.0092 16.5 0.0 0.034 14.7 0.0 2.1 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ10288.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 OAJ10290.1 - 5.4e-23 80.9 0.0 9.9e-16 57.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10290.1 - 2.6e-16 59.8 0.0 4.5e-10 39.8 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10290.1 - 4.1e-14 52.4 0.0 8.1e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10290.1 - 7.7e-09 35.8 0.0 2.1e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10290.1 - 0.056 13.7 0.2 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger Helicase_C PF00271.31 OAJ10296.1 - 5.5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ10296.1 - 0.00029 20.7 0.0 0.00078 19.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C2H2_4 PF13894.6 OAJ10296.1 - 0.0036 18.0 4.5 0.04 14.8 1.6 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ10296.1 - 0.026 15.0 0.9 0.026 15.0 0.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 OAJ10296.1 - 0.12 12.6 6.7 0.57 10.5 0.3 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding EthD PF07110.11 OAJ10296.1 - 0.15 13.2 0.2 6.7 7.9 0.0 3.3 3 0 0 3 3 3 0 EthD domain Zn-ribbon_8 PF09723.10 OAJ10296.1 - 0.32 11.2 6.2 0.52 10.5 1.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 OAJ10296.1 - 0.85 9.1 2.5 14 5.3 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 OAJ10296.1 - 2.9 8.5 7.9 1.1 9.8 1.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain RVT_1 PF00078.27 OAJ10301.1 - 3.2e-15 56.3 0.0 5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CAV_VP3 PF04771.12 OAJ10301.1 - 0.034 14.3 0.2 5.8 7.1 0.1 2.5 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein CENP-F_leu_zip PF10473.9 OAJ10305.1 - 0.00033 20.7 9.4 0.00033 20.7 9.4 2.8 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 OAJ10305.1 - 0.0021 18.6 9.8 0.0021 18.6 9.8 2.5 2 0 0 2 2 2 1 Apg6 coiled-coil region EzrA PF06160.12 OAJ10305.1 - 0.0036 15.6 3.7 0.0064 14.7 3.7 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA JIP_LZII PF16471.5 OAJ10305.1 - 0.017 15.3 2.2 0.017 15.3 2.2 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II YgaB PF14182.6 OAJ10305.1 - 0.029 14.8 1.3 0.098 13.1 1.3 1.9 1 0 0 1 1 1 0 YgaB-like protein DUF5320 PF17253.2 OAJ10305.1 - 0.14 13.2 0.7 0.57 11.3 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) BLOC1_2 PF10046.9 OAJ10305.1 - 0.38 11.1 3.8 0.97 9.8 0.6 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 OAJ10305.1 - 0.84 7.5 2.7 1.5 6.6 2.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 OAJ10305.1 - 2.6 7.4 16.0 0.29 10.4 3.3 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 OAJ10305.1 - 4.6 7.0 7.9 0.24 11.2 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TolA_bind_tri PF16331.5 OAJ10305.1 - 8.5 6.5 15.1 0.52 10.4 7.9 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation Glyco_hydro_9 PF00759.19 OAJ10306.1 - 1.3e-94 317.9 7.7 1.3e-94 317.9 7.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 PP2C PF00481.21 OAJ10306.1 - 4.9e-12 46.0 0.0 7.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Tyrosinase PF00264.20 OAJ10325.1 - 1.2e-33 117.3 5.0 1.2e-33 117.3 5.0 2.2 2 0 0 2 2 2 1 Common central domain of tyrosinase Med19 PF10278.9 OAJ10325.1 - 0.06 13.3 13.5 0.094 12.6 13.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Afi1 PF07792.12 OAJ10325.1 - 0.2 12.1 17.6 0.4 11.1 17.6 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_pol_Rpc4 PF05132.14 OAJ10325.1 - 0.26 11.7 14.1 0.46 10.9 14.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 OAJ10325.1 - 0.63 9.8 20.6 0.87 9.4 20.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 OAJ10325.1 - 0.87 9.7 4.5 1.6 8.9 4.5 1.4 1 0 0 1 1 1 0 DDHD domain Mpp10 PF04006.12 OAJ10325.1 - 0.88 7.9 35.0 1.1 7.6 35.0 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 OAJ10325.1 - 1 8.1 12.3 1.3 7.8 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.6 OAJ10325.1 - 1.1 9.4 13.5 2.3 8.3 13.5 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 OAJ10325.1 - 1.3 7.4 2.4 1.7 7.0 2.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nop14 PF04147.12 OAJ10325.1 - 1.8 6.7 36.4 2.2 6.4 36.4 1.1 1 0 0 1 1 1 0 Nop14-like family V_ATPase_I PF01496.19 OAJ10325.1 - 2 6.2 16.4 2.8 5.7 16.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cellulose_synt PF03552.14 OAJ10325.1 - 2.2 6.7 3.3 3.2 6.1 3.3 1.1 1 0 0 1 1 1 0 Cellulose synthase BORG_CEP PF14957.6 OAJ10325.1 - 2.6 9.2 11.4 4.8 8.4 11.4 1.4 1 0 0 1 1 1 0 Cdc42 effector TFIIF_alpha PF05793.12 OAJ10325.1 - 3.4 6.2 37.1 4.8 5.7 37.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GAGA_bind PF06217.12 OAJ10325.1 - 5.6 7.2 9.4 8 6.7 9.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIP PF07454.11 OAJ10325.1 - 6.6 6.1 19.4 13 5.2 19.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Astro_capsid_p PF12226.8 OAJ10325.1 - 7.8 5.5 29.7 14 4.7 29.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Helicase_C PF00271.31 OAJ10333.1 - 1.7e-11 44.5 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Proteasome PF00227.26 OAJ10340.1 - 1.3e-41 142.2 0.1 1.6e-41 141.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit DnaJ-X PF14308.6 OAJ10341.1 - 5.3e-63 212.3 0.3 5.3e-63 212.3 0.3 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 OAJ10341.1 - 4.8e-17 61.9 0.7 1.8e-16 60.0 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Ndc1_Nup PF09531.10 OAJ10341.1 - 4.4 5.9 7.5 0.54 8.9 3.6 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup EcKinase PF02958.20 OAJ10352.1 - 9.9e-12 44.8 0.0 3.7e-10 39.6 0.0 2.6 1 1 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 OAJ10352.1 - 2.3e-07 30.0 0.0 3.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 OAJ10352.1 - 7.8e-07 29.3 1.0 1.6e-06 28.2 1.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4407 PF14362.6 OAJ10353.1 - 0.22 10.9 9.1 1 8.7 5.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Syndecan PF01034.20 OAJ10361.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 OAJ10361.1 - 0.074 12.5 0.0 0.074 12.5 0.0 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Apt1 PF10351.9 OAJ10362.1 - 1 8.1 7.9 1.3 7.8 7.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 OAJ10362.1 - 3.8 5.7 9.7 5 5.3 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RVT_1 PF00078.27 OAJ10374.1 - 1.7e-23 83.3 0.0 3.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10374.1 - 2.1e-14 53.4 0.0 8.5e-12 45.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10374.1 - 5.3e-14 52.1 0.0 9.4e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10374.1 - 3e-12 46.8 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ10374.1 - 0.00012 22.3 0.0 0.021 15.1 0.0 2.6 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Strep_pep PF14404.6 OAJ10374.1 - 0.18 12.1 0.0 0.58 10.5 0.0 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species Asp_protease_2 PF13650.6 OAJ10375.1 - 0.0021 18.7 0.0 0.0045 17.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10375.1 - 0.0029 18.1 0.1 0.023 15.2 0.1 2.3 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Zn_ribbon_17 PF17120.5 OAJ10381.1 - 0.038 13.6 7.5 0.093 12.4 7.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ntox3 PF15536.6 OAJ10381.1 - 0.044 13.8 0.3 0.06 13.4 0.3 1.2 1 0 0 1 1 1 0 Bacterial toxin 3 HSP70 PF00012.20 OAJ10383.1 - 1.9e-06 26.4 0.0 2.3e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Rax2 PF12768.7 OAJ10391.1 - 2.5e-37 128.5 0.7 3.2e-35 121.6 0.0 4.2 5 0 0 5 5 5 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 OAJ10391.1 - 9e-15 54.0 0.0 1.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ10391.1 - 4.8e-12 45.6 0.0 9.6e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ10391.1 - 9.8e-07 28.4 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ10391.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Kelch_2 PF07646.15 OAJ10391.1 - 0.14 12.2 6.1 11 6.2 0.0 4.8 5 0 0 5 5 5 0 Kelch motif LapA_dom PF06305.11 OAJ10391.1 - 0.87 9.4 3.4 2.4 8.0 3.4 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain zf-C2H2 PF00096.26 OAJ10396.1 - 0.62 10.6 5.2 1.5 9.5 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Shadoo PF14999.6 OAJ10405.1 - 0.0099 16.0 0.2 0.095 12.8 0.0 2.3 1 1 1 2 2 2 1 Shadow of prion protein, neuroprotective DUF282 PF03380.14 OAJ10405.1 - 1.2 9.1 4.2 8.3 6.4 0.2 2.8 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Helitron_like_N PF14214.6 OAJ10412.1 - 9e-12 45.6 0.0 2.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ10412.1 - 3.3e-10 39.7 0.0 5.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.16 OAJ10423.1 - 2.9e-32 112.0 29.9 9.3e-31 107.0 8.0 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ10423.1 - 7.1e-10 38.3 0.5 7.1e-10 38.3 0.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 OAJ10423.1 - 0.0053 16.1 5.2 0.0053 16.1 5.2 2.9 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB PGA2 PF07543.12 OAJ10423.1 - 3.5 7.6 9.8 8.3 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 RT_RNaseH_2 PF17919.1 OAJ10427.1 - 2.3e-19 69.3 0.0 4.5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10427.1 - 5.5e-19 68.4 0.0 1.3e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10427.1 - 1.3e-14 54.3 0.2 2.3e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ10427.1 - 8.5e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ10427.1 - 0.00013 22.5 0.0 0.00031 21.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 OAJ10427.1 - 0.00016 21.6 1.5 0.00035 20.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ10427.1 - 0.00048 20.0 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ10427.1 - 0.0026 17.5 0.5 0.0026 17.5 0.5 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ10427.1 - 0.0041 16.9 0.5 0.0088 15.8 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 OAJ10427.1 - 0.046 14.0 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 OAJ10427.1 - 0.1 13.2 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease CLIP1_ZNF PF16641.5 OAJ10427.1 - 0.54 10.2 2.6 0.45 10.5 0.7 1.9 2 0 0 2 2 2 0 CLIP1 zinc knuckle Trimer_CC PF08954.11 OAJ10430.1 - 0.14 11.8 0.4 0.49 10.0 0.4 1.9 1 0 0 1 1 1 0 Trimerisation motif USP7_ICP0_bdg PF12436.8 OAJ10437.1 - 1.6e-81 273.2 0.0 7.1e-81 271.0 0.0 2.1 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 OAJ10437.1 - 2.9e-63 213.3 3.6 3.2e-62 209.9 0.4 3.0 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 OAJ10437.1 - 2.1e-50 171.6 0.0 6.7e-50 170.0 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ10437.1 - 1.1e-23 84.4 0.1 4e-23 82.5 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 OAJ10437.1 - 2.7e-08 33.9 0.0 1.5e-07 31.5 0.0 2.3 2 1 0 2 2 2 1 MATH domain Peptidase_S51 PF03575.17 OAJ10438.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S51 SF3A2 PF16835.5 OAJ10443.1 - 8.2e-29 99.8 0.0 1e-25 89.9 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 OAJ10443.1 - 1.5e-06 28.4 0.7 3.2e-06 27.3 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Linocin_M18 PF04454.12 OAJ10443.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase ATP_transf PF09830.9 OAJ10444.1 - 8.5e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 OAJ10444.1 - 0.019 15.7 0.0 0.062 14.0 0.0 1.8 1 0 0 1 1 1 0 HIT domain TBP PF00352.21 OAJ10445.1 - 1.4e-67 223.6 0.2 1.6e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAJ10445.1 - 1.2e-05 25.4 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAJ10445.1 - 0.07 13.0 0.2 0.62 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Asp PF00026.23 OAJ10455.1 - 1.3e-15 57.6 0.0 2.6e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AAA_5 PF07728.14 OAJ10456.1 - 1.1e-26 93.4 0.0 2.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ10456.1 - 0.0025 18.2 0.2 1.1 9.7 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ10456.1 - 0.0078 16.5 0.0 0.078 13.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain HI0933_like PF03486.14 OAJ10456.1 - 0.07 11.8 2.0 0.12 11.1 2.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ABC_membrane PF00664.23 OAJ10461.1 - 3.8e-73 246.5 23.2 5e-38 131.3 9.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ10461.1 - 4.5e-59 198.9 0.0 5.9e-29 101.3 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ10461.1 - 1.5e-16 60.5 1.9 3.7e-08 33.1 0.5 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ10461.1 - 2.1e-09 37.5 0.1 0.0015 18.5 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 OAJ10461.1 - 2.5e-07 30.8 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ10461.1 - 2.8e-07 30.2 2.5 0.0019 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ10461.1 - 7.2e-06 26.3 0.3 0.036 14.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 OAJ10461.1 - 3.5e-05 24.3 0.2 0.044 14.3 0.1 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 OAJ10461.1 - 0.00019 21.9 5.5 0.095 13.1 1.4 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 OAJ10461.1 - 0.00028 20.5 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ10461.1 - 0.0003 21.0 0.9 0.025 14.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 OAJ10461.1 - 0.00045 19.2 0.3 0.3 9.8 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 OAJ10461.1 - 0.002 17.7 0.5 0.41 10.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 OAJ10461.1 - 0.0022 18.4 0.3 0.69 10.3 0.0 3.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 OAJ10461.1 - 0.0027 17.5 0.1 0.61 9.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ10461.1 - 0.0034 17.4 0.1 4 7.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 OAJ10461.1 - 0.0037 17.8 2.3 0.14 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF3987 PF13148.6 OAJ10461.1 - 0.0063 15.6 5.8 0.039 13.0 1.2 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3987) T2SSE PF00437.20 OAJ10461.1 - 0.01 14.9 0.0 0.2 10.7 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF87 PF01935.17 OAJ10461.1 - 0.023 14.8 0.7 0.51 10.4 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 OAJ10461.1 - 0.031 14.5 4.6 2.1 8.7 0.3 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 OAJ10461.1 - 0.041 13.2 1.6 0.83 8.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.22 OAJ10461.1 - 0.056 13.8 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Hep_59 PF07052.11 OAJ10461.1 - 0.075 13.8 0.8 0.24 12.2 0.8 1.8 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 IstB_IS21 PF01695.17 OAJ10461.1 - 0.092 12.5 0.0 5 6.8 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 OAJ10461.1 - 0.11 12.5 0.0 4.2 7.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 OAJ10461.1 - 0.13 12.3 0.8 16 5.5 0.1 2.8 3 0 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 OAJ10461.1 - 1.2 8.5 3.8 6 6.1 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sugar_tr PF00083.24 OAJ10468.1 - 9.1e-09 34.7 0.1 1.4e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ATP-synt_DE_N PF02823.16 OAJ10468.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain adh_short PF00106.25 OAJ10469.1 - 1.9e-17 63.4 0.3 2e-17 63.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ10469.1 - 1e-14 54.7 0.2 1.4e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PIGA PF08288.12 OAJ10473.1 - 2.5e-40 136.9 0.0 5.2e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 OAJ10473.1 - 2.7e-29 102.3 1.1 4.8e-29 101.5 1.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 OAJ10473.1 - 7.5e-23 80.9 0.0 1.1e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ10473.1 - 1.1e-19 71.2 0.0 2.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 OAJ10473.1 - 3e-14 53.8 1.2 7.4e-14 52.5 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 OAJ10473.1 - 8.8e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 OAJ10473.1 - 0.0021 18.4 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tho1_MOS11_C PF18592.1 OAJ10474.1 - 1.1e-09 37.9 13.0 4.6e-08 32.7 0.2 3.1 2 1 1 3 3 3 3 Tho1/MOS11 C-terminal domain RT_RNaseH_2 PF17919.1 OAJ10487.1 - 4.1e-22 78.1 0.0 2e-13 50.2 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10487.1 - 6e-17 61.9 0.0 4.6e-11 42.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10487.1 - 9.8e-15 54.4 0.0 2.2e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10487.1 - 1e-11 45.1 0.0 1.9e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ10487.1 - 3.6e-06 26.7 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.17 OAJ10487.1 - 0.097 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Asp_protease_2 PF13650.6 OAJ10488.1 - 0.00033 21.2 0.0 0.00081 20.0 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ10488.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 OAJ10488.1 - 0.077 13.6 0.0 0.22 12.1 0.0 1.8 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ10488.1 - 0.11 12.8 0.0 1.5 9.2 0.0 2.6 2 1 0 2 2 2 0 Retroviral aspartyl protease PsbH PF00737.20 OAJ10496.1 - 0.24 11.2 3.0 10 5.9 0.3 2.5 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein DUF2975 PF11188.8 OAJ10496.1 - 3.3 7.6 9.4 1.2 9.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) RVT_1 PF00078.27 OAJ10504.1 - 1.9e-30 106.0 0.0 2.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ10504.1 - 5.2e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ10504.1 - 2.3e-05 24.1 0.3 7.8e-05 22.3 0.3 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Flavi_NS2B PF01002.19 OAJ10505.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B RVT_1 PF00078.27 OAJ10507.1 - 5.5e-20 71.8 0.0 9.7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10507.1 - 3.6e-14 52.6 0.6 8.9e-14 51.3 0.2 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 OAJ10507.1 - 4.8e-14 52.6 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ10507.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ10507.1 - 0.034 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 OAJ10507.1 - 0.17 12.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Zinc knuckle PPI_Ypi1 PF07491.11 OAJ10517.1 - 2.6e-23 81.6 4.2 2.6e-23 81.6 4.2 2.6 2 1 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.14 OAJ10517.1 - 0.67 8.2 11.3 1.4 7.1 11.3 1.5 1 1 0 1 1 1 0 CDC45-like protein Histidinol_dh PF00815.20 OAJ10518.1 - 2.4e-158 527.5 0.3 4.1e-158 526.7 0.3 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 OAJ10518.1 - 3.8e-21 74.7 0.2 7.3e-21 73.8 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 OAJ10518.1 - 5.1e-15 55.7 0.6 3.6e-14 53.0 1.3 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 OAJ10518.1 - 0.0028 17.8 0.2 0.0059 16.8 0.2 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain DUF460 PF04312.13 OAJ10518.1 - 0.0076 16.0 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF460) MazG-like PF12643.7 OAJ10518.1 - 0.081 13.2 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 MazG-like family Helicase_C PF00271.31 OAJ10527.1 - 2.1e-13 50.6 0.0 3.7e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_integrase PF00589.22 OAJ10527.1 - 0.13 12.1 0.0 20 4.9 0.0 2.3 2 0 0 2 2 2 0 Phage integrase family Paramyxo_PNT PF14320.6 OAJ10533.1 - 0.055 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PNT disordered MULE PF10551.9 OAJ10535.1 - 1.1e-22 80.3 0.1 9.3e-22 77.3 0.0 2.4 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 OAJ10535.1 - 5.8e-06 25.4 0.0 8.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Fis1_TPR_N PF14852.6 OAJ10535.1 - 0.083 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat PDZ_5 PF17817.1 OAJ10541.1 - 0.07 13.4 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Ycf9 PF01737.17 OAJ10542.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 YCF9 MHB PF16525.5 OAJ10546.1 - 0.037 14.3 0.0 4.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Haemophore, haem-binding PQQ PF01011.21 OAJ10547.1 - 0.0021 17.9 1.1 0.22 11.5 0.1 3.3 3 0 0 3 3 3 2 PQQ enzyme repeat F-box PF00646.33 OAJ10548.1 - 2.8e-05 23.9 0.4 4.6e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 F-box domain DUF4075 PF13294.6 OAJ10557.1 - 0.048 13.8 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Dimer_Tnp_hAT PF05699.14 OAJ10562.1 - 3.1e-14 52.5 0.1 6.6e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CorA PF01544.18 OAJ10562.1 - 0.13 11.6 2.4 0.24 10.7 2.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 OAJ10563.1 - 4.3e-40 137.7 0.0 6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10563.1 - 2.5e-17 63.0 0.0 4.5e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10563.1 - 2.7e-06 26.9 0.0 5.6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like adh_short_C2 PF13561.6 OAJ10569.1 - 1.2e-30 106.8 0.1 1.3e-30 106.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ10569.1 - 6e-14 51.9 0.1 7.4e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DDOST_48kD PF03345.14 OAJ10570.1 - 4.6e-100 335.4 0.0 1.6e-99 333.6 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF347 PF03988.12 OAJ10570.1 - 1 9.6 5.7 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Phosphodiest PF01663.22 OAJ10571.1 - 9.8e-05 22.1 0.1 0.00018 21.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase zf-TFIIB PF13453.6 OAJ10571.1 - 0.0041 16.4 0.0 0.0084 15.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor zinc-finger RLAN PF14401.6 OAJ10580.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATPgrasp N-terminal domain HSNSD PF12062.8 OAJ10580.1 - 0.011 14.5 0.1 0.014 14.2 0.1 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase DUF4413 PF14372.6 OAJ10581.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.25 OAJ10582.1 - 1.8e-27 96.4 0.0 2e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10582.1 - 1.9e-16 60.2 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10582.1 - 5.7e-06 25.9 0.0 1.2e-05 24.8 0.0 1.4 1 1 1 2 2 2 1 Kinase-like DUF1899 PF08953.11 OAJ10591.1 - 1.4e-30 105.0 0.7 3.4e-30 103.7 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 OAJ10591.1 - 1.1e-18 66.8 0.9 5.2e-17 61.5 0.3 2.6 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 OAJ10591.1 - 4.8e-10 39.9 7.1 0.057 14.3 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ10591.1 - 0.0056 16.9 0.0 21 5.5 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ10591.1 - 0.013 14.4 0.0 0.9 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 OAJ10591.1 - 0.052 12.6 0.0 0.13 11.3 0.0 1.6 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain RNA_pol_Rpb8 PF03870.15 OAJ10592.1 - 5.8e-45 152.9 0.0 8e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 OAJ10592.1 - 0.0099 15.9 0.0 4.2 7.5 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G polyprenyl_synt PF00348.17 OAJ10593.1 - 1.4e-53 181.6 0.0 5.1e-27 94.6 0.0 2.3 2 1 0 2 2 2 2 Polyprenyl synthetase zinc_ribbon_10 PF10058.9 OAJ10594.1 - 4.1e-07 29.6 0.0 8.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein SOG2 PF10428.9 OAJ10594.1 - 5.3 6.1 10.0 7.7 5.6 10.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.13 OAJ10594.1 - 5.8 6.8 17.6 8.2 6.3 17.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fe-ADH PF00465.19 OAJ10600.1 - 3.2e-94 315.8 0.0 4.1e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ10600.1 - 1.8e-12 47.5 0.0 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase SH3_9 PF14604.6 OAJ10601.1 - 2.6e-05 24.0 0.3 0.00052 19.8 0.3 2.4 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ10601.1 - 3.8e-05 23.2 0.1 0.00017 21.1 0.0 2.1 2 0 0 2 2 2 1 SH3 domain Proteasome PF00227.26 OAJ10602.1 - 2.3e-60 203.3 0.0 3.8e-60 202.6 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ10602.1 - 2.5e-09 36.6 0.2 7.6e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature SH2_2 PF14633.6 OAJ10616.1 - 3e-75 252.3 0.1 3e-75 252.3 0.1 2.0 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 OAJ10616.1 - 3.3e-23 82.0 0.0 6.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 OAJ10616.1 - 1.1e-19 70.7 1.3 5.4e-13 49.0 0.0 2.9 3 0 0 3 3 3 2 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 OAJ10616.1 - 2e-16 60.3 26.0 2e-16 60.3 26.0 7.2 7 1 1 8 8 8 2 Acidic N-terminal SPT6 HTH_44 PF14641.6 OAJ10616.1 - 4.4e-09 36.8 0.1 4.4e-08 33.5 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.24 OAJ10616.1 - 0.00064 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain ADPRTs_Tse2 PF18648.1 OAJ10616.1 - 0.0053 16.8 2.0 0.021 14.9 2.0 2.0 1 0 0 1 1 1 1 Tse2 ADP-ribosyltransferase toxins HHH_3 PF12836.7 OAJ10616.1 - 0.03 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif CTD PF12815.7 OAJ10616.1 - 0.063 13.9 8.9 2.8 8.6 3.5 2.4 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HHH_9 PF17674.1 OAJ10616.1 - 3.2 8.7 6.7 0.32 11.9 0.1 3.0 3 1 0 3 3 3 0 HHH domain Uds1 PF15456.6 OAJ10624.1 - 0.0059 16.8 1.1 0.0087 16.2 1.1 1.3 1 0 0 1 1 1 1 Up-regulated During Septation Spectrin PF00435.21 OAJ10624.1 - 0.011 16.2 0.9 0.022 15.2 0.9 1.5 1 1 0 1 1 1 0 Spectrin repeat bZIP_1 PF00170.21 OAJ10624.1 - 0.017 15.2 3.7 0.022 14.8 0.5 2.1 1 1 1 2 2 2 0 bZIP transcription factor BDV_P24 PF06595.11 OAJ10624.1 - 0.063 13.2 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein DUF3138 PF11336.8 OAJ10624.1 - 0.15 10.6 0.8 0.2 10.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fzo_mitofusin PF04799.13 OAJ10624.1 - 0.29 10.7 6.4 0.032 13.8 2.3 1.5 2 0 0 2 2 2 0 fzo-like conserved region RT_RNaseH_2 PF17919.1 OAJ10633.1 - 6.8e-33 112.7 0.0 1.3e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10633.1 - 1.9e-29 102.0 0.0 3.8e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10633.1 - 3.1e-08 33.4 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10634.1 - 1.5e-16 60.7 0.1 3.4e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ10634.1 - 5.7e-13 48.8 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ10634.1 - 0.0037 17.0 0.0 0.0094 15.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ10634.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 H2C2 zinc finger zf-CCHC PF00098.23 OAJ10635.1 - 0.0047 16.9 2.0 0.0085 16.1 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle FANCF PF11107.8 OAJ10635.1 - 0.0059 15.9 0.0 0.029 13.6 0.0 1.9 1 1 1 2 2 2 1 Fanconi anemia group F protein (FANCF) Asp_protease_2 PF13650.6 OAJ10635.1 - 0.04 14.5 0.0 0.089 13.4 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.27 OAJ10644.1 - 9.4e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10644.1 - 4.5e-22 78.0 0.0 1.1e-13 51.0 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10644.1 - 1.2e-15 57.3 0.0 2.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ10644.1 - 2.1e-15 56.9 0.0 2.2e-10 40.7 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10644.1 - 1.7e-11 44.4 0.0 6.4e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10644.1 - 5.8e-05 23.7 0.0 0.00017 22.2 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10644.1 - 0.0036 17.8 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBM PF14377.6 OAJ10645.1 - 0.078 12.5 0.2 0.2 11.2 0.2 1.7 1 0 0 1 1 1 0 Ubiquitin binding region Pkinase PF00069.25 OAJ10653.1 - 1.2e-65 221.5 0.1 6e-60 202.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10653.1 - 3.4e-36 124.8 0.1 2.5e-33 115.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 OAJ10653.1 - 4.1e-17 61.7 0.4 6.9e-17 61.0 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 OAJ10653.1 - 6.1e-05 22.5 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ10653.1 - 0.00018 21.5 0.8 0.0053 16.7 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ10653.1 - 0.0012 17.9 0.1 0.0019 17.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ10653.1 - 0.0052 16.1 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Ribosomal_L7Ae PF01248.26 OAJ10661.1 - 1.1e-26 92.4 1.3 4.4e-26 90.4 1.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Phage_integrase PF00589.22 OAJ10661.1 - 5.5e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF2716 PF10898.8 OAJ10661.1 - 0.095 13.1 0.2 0.22 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) Ribosomal_S17_N PF16205.5 OAJ10662.1 - 8.6e-31 106.1 1.1 9.9e-31 105.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 OAJ10662.1 - 6.8e-27 93.4 0.3 6.8e-27 93.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Syntaxin_2 PF14523.6 OAJ10669.1 - 0.32 11.4 1.9 0.55 10.6 0.1 2.3 3 0 0 3 3 3 0 Syntaxin-like protein zf-C2H2_2 PF12756.7 OAJ10670.1 - 0.088 13.2 0.2 0.63 10.4 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Sec1 PF00995.23 OAJ10675.1 - 1.6e-111 374.4 0.0 1.9e-111 374.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Vma12 PF11712.8 OAJ10676.1 - 0.68 10.0 2.5 18 5.4 2.0 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Aida_N PF08910.10 OAJ10676.1 - 9.9 6.6 9.2 0.45 10.9 1.2 2.7 3 0 0 3 3 3 0 Aida N-terminus Filament_head PF04732.14 OAJ10681.1 - 0.031 15.1 2.0 0.031 15.1 2.0 3.0 1 1 2 3 3 3 0 Intermediate filament head (DNA binding) region Transposase_21 PF02992.14 OAJ10682.1 - 8.2e-05 21.9 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ10683.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TrbI_Ftype PF09677.10 OAJ10683.1 - 0.053 13.8 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Collagen PF01391.18 OAJ10690.1 - 4.1e-48 161.0 305.8 2.1e-09 37.0 31.0 8.8 3 3 5 8 8 8 7 Collagen triple helix repeat (20 copies) AMP-binding PF00501.28 OAJ10691.1 - 3.7e-82 276.2 0.0 4.6e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EspB_PE PF18625.1 OAJ10695.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ESX-1 secreted protein B PE domain Glyco_hydro_52 PF03512.13 OAJ10697.1 - 0.26 10.2 0.6 0.43 9.5 0.6 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 CAS_CSE1 PF03378.15 OAJ10705.1 - 3.1e-126 421.5 0.0 4.9e-126 420.8 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 OAJ10705.1 - 7.9e-118 393.5 0.0 1.3e-117 392.7 0.0 1.4 1 0 0 1 1 1 1 Cse1 ubiquitin PF00240.23 OAJ10711.1 - 1.1e-20 73.1 0.3 1.8e-20 72.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 OAJ10711.1 - 3e-14 52.6 4.3 2e-07 30.8 0.7 2.8 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 OAJ10711.1 - 2e-12 46.7 13.9 3.9e-12 45.7 13.9 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 OAJ10711.1 - 9.6e-06 25.3 0.5 1.5e-05 24.7 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 OAJ10711.1 - 0.001 19.2 0.1 0.0021 18.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 OAJ10711.1 - 0.0076 16.0 0.0 0.3 10.9 0.0 2.7 2 0 0 2 2 2 1 UBA-like domain Ubiquitin_5 PF18037.1 OAJ10711.1 - 0.0088 16.4 0.2 0.019 15.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain MCM_N PF14551.6 OAJ10711.1 - 0.025 15.2 0.2 0.07 13.7 0.1 1.7 2 0 0 2 2 2 0 MCM N-terminal domain DUF2407 PF10302.9 OAJ10711.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CSTF2_hinge PF14327.6 OAJ10711.1 - 0.19 12.2 5.1 7.1 7.2 5.4 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Med13_C PF06333.12 OAJ10711.1 - 0.49 9.6 4.9 0.79 8.9 4.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Ndc1_Nup PF09531.10 OAJ10711.1 - 0.63 8.7 1.6 0.64 8.6 1.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.11 OAJ10711.1 - 1.8 6.8 5.2 2.3 6.4 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) eIF3m_C_helix PF18005.1 OAJ10712.1 - 8.8e-07 28.5 0.6 2.1e-06 27.3 0.6 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 OAJ10712.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain RVT_2 PF07727.14 OAJ10722.1 - 1.6e-59 201.5 0.0 2.2e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10722.1 - 4.6e-17 62.3 0.3 1.9e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10722.1 - 1.3e-08 34.6 0.4 1.7e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ10722.1 - 2.1e-08 34.0 0.0 4.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ10722.1 - 4.2e-05 23.4 7.6 0.012 15.6 0.9 2.5 2 0 0 2 2 2 2 Zinc knuckle rve_3 PF13683.6 OAJ10722.1 - 0.0014 18.3 0.0 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RNA_bind PF08675.11 OAJ10722.1 - 0.063 13.3 0.2 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain DUF1820 PF08850.11 OAJ10722.1 - 0.073 13.6 0.1 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1820) zf-CCHC_3 PF13917.6 OAJ10722.1 - 0.71 9.9 2.6 11 6.1 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 OAJ10731.1 - 5.2e-12 46.0 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10731.1 - 4.5e-06 26.6 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ10731.1 - 1.1e-05 25.9 0.0 3.1e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10731.1 - 0.00082 19.9 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ10731.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease WD40 PF00400.32 OAJ10739.1 - 5.2e-12 46.1 5.3 0.0044 17.8 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ10739.1 - 1.2e-05 25.5 0.0 0.055 13.8 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ10739.1 - 0.083 11.5 0.6 0.38 9.3 0.1 2.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Ras PF00071.22 OAJ10740.1 - 1e-53 181.3 0.0 1.1e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ10740.1 - 4e-19 69.0 0.0 5.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ10740.1 - 1.9e-06 27.4 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ10740.1 - 0.14 11.7 0.1 1.2 8.6 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AhpC-TSA_2 PF13911.6 OAJ10749.1 - 1.3e-12 47.8 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ10749.1 - 1.4e-07 31.4 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ10749.1 - 1.5e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family zf-RING_2 PF13639.6 OAJ10756.1 - 2.3e-08 34.2 6.0 8.1e-07 29.3 0.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ10756.1 - 6.1e-06 26.0 5.6 6.9e-06 25.8 0.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ10756.1 - 3e-05 23.8 3.0 0.00046 20.0 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ10756.1 - 4.1e-05 23.8 0.1 4.1e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ10756.1 - 8.3e-05 22.4 0.5 8.3e-05 22.4 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 OAJ10756.1 - 0.00018 21.0 0.8 0.00036 20.1 0.8 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAJ10756.1 - 0.00021 21.2 2.6 0.00067 19.6 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Spt20 PF12090.8 OAJ10756.1 - 0.0017 18.0 9.7 0.0017 18.0 9.7 1.9 2 0 0 2 2 2 1 Spt20 family zf-C3HC4_3 PF13920.6 OAJ10756.1 - 0.0047 16.8 4.2 0.0088 15.9 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ10756.1 - 0.0081 16.2 12.7 0.0089 16.0 1.9 2.9 2 1 1 3 3 3 1 RING-type zinc-finger RAB3GAP2_N PF14655.6 OAJ10756.1 - 0.012 14.9 2.3 0.019 14.2 2.3 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-ANAPC11 PF12861.7 OAJ10756.1 - 0.041 13.9 0.2 0.041 13.9 0.2 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ10756.1 - 0.051 13.3 3.3 0.74 9.6 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 OAJ10756.1 - 0.063 13.6 0.3 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 RING-like domain LIM_bind PF01803.16 OAJ10756.1 - 0.16 11.5 4.5 3.6 7.1 0.1 2.3 2 0 0 2 2 2 0 LIM-domain binding protein zf-Nse PF11789.8 OAJ10756.1 - 0.22 11.4 1.3 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 OAJ10756.1 - 0.36 11.0 7.8 0.37 11.0 3.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain Rad50_zn_hook PF04423.14 OAJ10756.1 - 1.1 9.2 4.3 1.6 8.7 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif RINGv PF12906.7 OAJ10756.1 - 3.8 7.7 6.8 0.37 10.9 1.5 2.0 2 0 0 2 2 2 0 RING-variant domain DUF4834 PF16118.5 OAJ10756.1 - 4.1 8.4 11.0 34 5.5 4.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) zf-C3HC4_4 PF15227.6 OAJ10756.1 - 4.5 7.5 7.8 1 9.6 0.2 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TetR_C_21 PF17926.1 OAJ10756.1 - 4.8 7.4 9.1 1.7 8.8 0.2 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TMEM132D_C PF15706.5 OAJ10756.1 - 6.4 6.6 5.7 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term RVT_1 PF00078.27 OAJ10761.1 - 6.3e-14 52.0 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ10761.1 - 0.25 10.8 2.8 1.2 8.6 2.8 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family OrgA_MxiK PF09482.10 OAJ10762.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) MMR_HSR1 PF01926.23 OAJ10769.1 - 5.4e-12 45.8 0.0 2.2e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ10769.1 - 0.00086 18.9 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ10769.1 - 0.0017 18.4 0.1 0.0058 16.7 0.1 1.9 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 OAJ10769.1 - 0.026 14.4 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SspB PF04386.13 OAJ10769.1 - 1.4 8.8 4.2 0.87 9.5 0.1 2.6 2 0 0 2 2 2 0 Stringent starvation protein B NPL4 PF05021.15 OAJ10770.1 - 4.2e-91 305.5 0.0 7e-89 298.2 0.0 3.2 2 1 0 2 2 2 1 NPL4 family zf-NPL4 PF05020.15 OAJ10770.1 - 7.4e-66 220.8 0.1 1.2e-65 220.1 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 OAJ10770.1 - 0.00024 21.5 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UIM PF02809.20 OAJ10770.1 - 0.0047 16.8 0.6 0.016 15.1 0.6 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif RVT_1 PF00078.27 OAJ10778.1 - 2e-22 79.8 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10778.1 - 1.2e-15 57.4 0.0 2.4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ10778.1 - 6.9e-14 51.7 0.0 2.5e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10778.1 - 1.8e-12 47.5 0.0 5.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10778.1 - 0.0014 19.2 0.1 0.0038 17.8 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ10778.1 - 0.0022 18.2 0.0 0.0056 16.9 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger gag-asp_proteas PF13975.6 OAJ10778.1 - 0.018 15.6 0.0 0.063 13.9 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 OAJ10778.1 - 0.022 15.0 0.0 0.068 13.5 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase dUTPase PF00692.19 OAJ10778.1 - 0.025 14.2 0.0 0.065 12.9 0.0 1.6 2 0 0 2 2 2 0 dUTPase Exc PF07825.11 OAJ10778.1 - 0.77 9.8 2.7 1.5 8.8 0.5 2.5 2 0 0 2 2 2 0 Excisionase-like protein Importin_rep_2 PF18786.1 OAJ10779.1 - 0.037 13.9 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Importin 13 repeat RVT_2 PF07727.14 OAJ10789.1 - 5e-60 203.2 0.0 7.2e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ10789.1 - 2.5e-16 59.9 0.0 1.1e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ10789.1 - 3e-06 27.0 0.0 3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ10789.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RdRP PF05183.12 OAJ10795.1 - 3.2e-166 554.4 0.0 4.5e-166 553.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase MULE PF10551.9 OAJ10804.1 - 9e-05 22.8 0.2 0.00023 21.5 0.2 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ10804.1 - 0.00012 21.6 0.1 0.00037 20.1 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger CDRN PF05174.12 OAJ10804.1 - 0.0057 16.3 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Cysteine-rich D. radiodurans N terminus RskA PF10099.9 OAJ10804.1 - 1.7 8.9 21.3 1.3 9.3 19.4 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA YL1 PF05764.13 OAJ10812.1 - 0.00039 20.6 14.0 0.00039 20.6 14.0 1.5 2 0 0 2 2 2 1 YL1 nuclear protein AD PF09793.9 OAJ10812.1 - 0.059 13.5 0.9 0.22 11.7 0.9 1.9 1 0 0 1 1 1 0 Anticodon-binding domain TSC22 PF01166.18 OAJ10812.1 - 0.078 13.3 0.8 0.078 13.3 0.8 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family CDC45 PF02724.14 OAJ10812.1 - 0.23 9.7 10.5 0.38 9.0 10.5 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ10812.1 - 0.34 10.3 13.9 0.032 13.6 9.6 1.5 2 0 0 2 2 2 0 SDA1 HET PF06985.11 OAJ10812.1 - 1.5 9.1 5.0 0.45 10.9 0.3 2.2 2 1 1 3 3 3 0 Heterokaryon incompatibility protein (HET) RVT_1 PF00078.27 OAJ10816.1 - 6.4e-27 94.5 0.0 9.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ10816.1 - 1.8e-18 66.5 0.2 4.5e-18 65.2 0.2 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ10816.1 - 8.5e-07 28.7 2.1 2.4e-06 27.2 2.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RecC_C PF17946.1 OAJ10816.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 RecC C-terminal domain NGF PF00243.18 OAJ10816.1 - 0.38 11.0 1.4 1 9.6 0.4 2.2 2 1 0 2 2 2 0 Nerve growth factor family zf-RVT PF13966.6 OAJ10818.1 - 7.8e-06 26.5 1.2 1.5e-05 25.6 1.2 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 OAJ10818.1 - 0.0011 19.1 0.1 0.0039 17.4 0.1 1.9 2 0 0 2 2 2 1 RNase H Ribosomal_60s PF00428.19 OAJ10818.1 - 6.3 7.5 14.2 3.7 8.2 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CTD PF12815.7 OAJ10825.1 - 0.0018 18.8 10.8 0.026 15.1 10.8 2.2 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 UCH PF00443.29 OAJ10826.1 - 1.1e-75 254.5 0.0 1.5e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 OAJ10826.1 - 4.2e-14 52.9 0.0 2.7e-13 50.3 0.0 2.4 3 0 0 3 3 3 1 DUSP domain UCH_1 PF13423.6 OAJ10826.1 - 1.9e-13 50.7 0.0 9e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 OAJ10826.1 - 8.7e-05 22.3 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal CW_binding_1 PF01473.20 OAJ10826.1 - 0.15 12.4 1.9 0.38 11.2 0.9 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat zf-FPG_IleRS PF06827.14 OAJ10826.1 - 0.22 11.4 1.1 4.6 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Velvet PF11754.8 OAJ10834.1 - 1.8e-43 149.3 0.0 1.6e-30 106.9 0.1 5.2 3 2 1 4 4 4 2 Velvet factor ENTH PF01417.20 OAJ10835.1 - 2.5e-47 160.0 0.0 6.3e-47 158.7 0.0 1.7 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 OAJ10835.1 - 0.00033 20.4 5.2 0.37 10.8 0.8 3.3 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 OAJ10835.1 - 0.21 10.5 11.1 0.0064 15.5 3.0 2.4 2 1 0 2 2 2 0 ANTH domain LSM PF01423.22 OAJ10836.1 - 5.8e-20 70.8 0.1 6.5e-20 70.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ10836.1 - 4.3e-06 26.8 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ10836.1 - 0.00058 19.9 0.1 0.00068 19.7 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain EBP PF05241.12 OAJ10843.1 - 0.32 10.4 8.0 0.87 9.0 8.0 1.6 1 1 0 1 1 1 0 Emopamil binding protein eIF2A PF08662.11 OAJ10844.1 - 8.1e-82 273.8 0.2 2e-79 266.0 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 OAJ10844.1 - 8.3e-06 26.4 0.9 0.66 11.0 0.2 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Proteasome_A_N PF10584.9 OAJ10844.1 - 0.047 13.4 0.8 14 5.5 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDV3 PF15359.6 OAJ10844.1 - 0.44 11.0 3.9 2.1 8.8 1.0 2.5 1 1 1 2 2 2 0 Carnitine deficiency-associated protein 3 IATP PF04568.12 OAJ10844.1 - 1 9.8 5.5 0.57 10.6 0.4 2.6 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Pkinase PF00069.25 OAJ10845.1 - 1.9e-63 214.3 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10845.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ10845.1 - 4.8e-07 29.9 0.6 2.6e-05 24.3 0.3 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ10845.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ10845.1 - 0.018 13.8 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 OAJ10845.1 - 0.019 14.6 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 OAJ10845.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ThiF PF00899.21 OAJ10850.1 - 4.3e-75 252.2 0.0 6.2e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 OAJ10850.1 - 1.9e-12 47.7 0.2 5.1e-06 26.6 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 OAJ10850.1 - 2e-05 25.1 0.0 0.00012 22.6 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 OAJ10850.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ10850.1 - 0.016 15.5 0.0 0.069 13.4 0.0 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 OAJ10850.1 - 0.063 13.7 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding P21-Arc PF04062.14 OAJ10857.1 - 1.7e-78 262.6 0.0 1.9e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit vATP-synt_E PF01991.18 OAJ10858.1 - 1.8e-60 203.8 14.2 2.1e-60 203.6 14.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 OAJ10858.1 - 3.2 7.6 6.1 1.8 8.4 3.5 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pyr_redox_2 PF07992.14 OAJ10859.1 - 1.1e-40 139.8 0.0 1.6e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ10859.1 - 2.3e-12 47.3 0.2 2.9e-08 34.2 0.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 OAJ10859.1 - 2.8e-08 33.0 3.1 0.00013 21.6 0.6 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ10859.1 - 4.2e-08 32.2 4.0 8e-05 21.9 1.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAJ10859.1 - 5.4e-08 33.2 0.2 0.002 18.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ10859.1 - 1.8e-05 24.0 2.8 0.0042 16.5 0.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 OAJ10859.1 - 0.0018 18.1 2.9 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair NAD_binding_7 PF13241.6 OAJ10859.1 - 0.015 15.7 0.5 4.3 7.8 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 OAJ10859.1 - 0.028 13.7 5.4 0.29 10.3 3.8 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.9 OAJ10859.1 - 0.23 11.8 1.5 6.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region CAP_N PF01213.19 OAJ10859.1 - 1.8 8.0 5.5 3.1 7.2 5.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 OAJ10859.1 - 4.3 7.4 5.2 9.4 6.3 5.2 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ubiquitin PF00240.23 OAJ10866.1 - 0.016 14.9 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family Holin_SPP1 PF04688.13 OAJ10867.1 - 0.059 13.6 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 SPP1 phage holin TP2 PF01254.18 OAJ10876.1 - 1.2 9.8 4.9 2.9 8.5 4.9 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 RVT_1 PF00078.27 OAJ10877.1 - 6.2e-23 81.5 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10877.1 - 9.5e-16 57.7 0.0 1.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ10877.1 - 4.5e-13 49.1 0.0 1.6e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ10877.1 - 6.7e-08 32.7 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10877.1 - 0.0047 17.5 0.1 0.011 16.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ10877.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ10877.1 - 0.19 12.0 0.0 0.7 10.2 0.0 2.0 2 0 0 2 2 2 0 H2C2 zinc finger RT_RNaseH PF17917.1 OAJ10878.1 - 3.3e-12 46.6 0.0 5.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10878.1 - 8.1e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10883.1 - 8.5e-24 84.3 0.0 1.5e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ10883.1 - 1.2e-22 79.8 0.3 1.6e-15 56.9 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ10883.1 - 3e-17 62.8 0.0 3.5e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ10883.1 - 1.6e-15 56.9 0.1 2.9e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10883.1 - 9e-10 38.8 0.0 2.9e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ10883.1 - 4.8e-05 23.9 0.0 0.00017 22.1 0.0 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10883.1 - 0.0046 17.5 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ10883.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Drc1-Sld2 PF11719.8 OAJ10890.1 - 2.2e-11 44.0 11.5 2.2e-11 44.0 11.5 5.5 4 2 2 6 6 6 1 DNA replication and checkpoint protein ALG3 PF05208.13 OAJ10891.1 - 5.4e-131 437.3 6.1 6.7e-131 437.0 6.1 1.1 1 0 0 1 1 1 1 ALG3 protein PBP PF01161.20 OAJ10892.1 - 6.3e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein KfrB PF18790.1 OAJ10892.1 - 0.057 13.7 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 KfrB protein PRR18 PF15671.5 OAJ10892.1 - 4.8 7.0 8.1 10 5.9 8.1 1.5 1 0 0 1 1 1 0 Proline-rich protein family 18 FAM72 PF14976.6 OAJ10899.1 - 3.8e-21 75.8 0.3 9.8e-21 74.4 0.3 1.6 2 0 0 2 2 2 1 FAM72 protein TetR_C_23 PF17931.1 OAJ10899.1 - 1.1 9.5 5.2 2 8.6 5.2 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Spt20 PF12090.8 OAJ10899.1 - 1.6 8.3 23.2 2.6 7.6 23.2 1.2 1 0 0 1 1 1 0 Spt20 family GST_N PF02798.20 OAJ10900.1 - 5.2e-16 58.8 0.0 1.6e-15 57.2 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ10900.1 - 2.4e-15 56.7 0.0 5.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ10900.1 - 3.2e-11 43.4 0.0 1.2e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ10900.1 - 7.9e-09 35.6 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ10900.1 - 5.8e-06 26.3 0.0 1.9e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ10900.1 - 0.0002 21.5 0.0 0.00067 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ10900.1 - 0.047 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAJ10900.1 - 0.095 13.5 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Retrotrans_gag PF03732.17 OAJ10908.1 - 6.5e-12 45.6 0.2 3.7e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ10908.1 - 3.8e-08 33.2 0.0 6.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) PBECR2 PF18810.1 OAJ10908.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 DUF2205 PF10224.9 OAJ10908.1 - 0.17 11.9 1.4 0.37 10.8 1.4 1.5 1 0 0 1 1 1 0 Short coiled-coil protein TSC22 PF01166.18 OAJ10908.1 - 0.22 11.9 2.4 0.36 11.2 1.0 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4140 PF13600.6 OAJ10908.1 - 0.33 11.4 3.7 5.1 7.6 3.2 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 OAJ10908.1 - 0.54 10.9 2.1 0.68 10.6 0.2 2.1 2 0 0 2 2 2 0 Initiation control protein YabA RT_RNaseH PF17917.1 OAJ10909.1 - 5e-36 123.2 0.3 9.4e-36 122.3 0.3 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ10909.1 - 2.5e-35 120.5 0.1 6.6e-35 119.2 0.1 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ10909.1 - 1.3e-32 113.2 0.1 2.3e-32 112.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ10909.1 - 5e-21 74.6 0.4 1.6e-20 72.9 0.4 2.0 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ10909.1 - 4.4e-15 55.9 0.0 1.5e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAJ10909.1 - 1.4e-08 34.5 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 OAJ10909.1 - 8.1e-05 23.2 0.0 0.00023 21.8 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ10909.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 OAJ10909.1 - 0.0012 19.0 0.0 0.0059 16.8 0.0 2.3 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 OAJ10909.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF5492 PF17596.2 OAJ10910.1 - 0.19 12.1 0.0 0.52 10.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5492) FHA PF00498.26 OAJ10917.1 - 0.0025 18.1 0.1 0.005 17.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 OAJ10918.1 - 0.081 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 FHA domain zf-HIT PF04438.16 OAJ10928.1 - 7.7e-08 32.1 9.6 1.3e-07 31.4 9.6 1.3 1 0 0 1 1 1 1 HIT zinc finger TRAM_LAG1_CLN8 PF03798.16 OAJ10929.1 - 4.4e-18 65.7 4.6 5.4e-18 65.4 4.6 1.0 1 0 0 1 1 1 1 TLC domain Aldose_epim PF01263.20 OAJ10930.1 - 2.9e-57 194.3 0.1 4.8e-57 193.5 0.1 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase Helitron_like_N PF14214.6 OAJ10940.1 - 1.7e-31 109.9 0.1 3.2e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ10942.1 - 1.7e-51 175.5 0.0 4.9e-51 174.0 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ10942.1 - 3.6e-11 43.1 0.0 1e-10 41.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ10942.1 - 1.7e-07 31.7 0.0 5.1e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 OAJ10942.1 - 0.00093 19.0 0.6 1.3 8.7 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 OAJ10942.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase MeaB PF03308.16 OAJ10942.1 - 0.058 12.4 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 OAJ10942.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Herpes_Helicase PF02689.14 OAJ10942.1 - 0.15 10.0 0.0 1.1 7.1 0.0 2.1 3 0 0 3 3 3 0 Helicase RPA_C PF08784.11 OAJ10942.1 - 0.18 12.5 0.0 26 5.5 0.0 2.6 2 0 0 2 2 2 0 Replication protein A C terminal Dimer_Tnp_hAT PF05699.14 OAJ10950.1 - 4e-13 48.9 0.0 1.3e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ10950.1 - 0.012 16.0 0.0 0.033 14.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) zf-BED PF02892.15 OAJ10950.1 - 0.012 15.6 1.3 0.012 15.6 1.3 2.2 3 0 0 3 3 3 0 BED zinc finger zinc_ribbon_11 PF11682.8 OAJ10950.1 - 0.036 14.1 0.1 0.089 12.8 0.1 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon Pkinase PF00069.25 OAJ10951.1 - 3e-41 141.6 0.0 3.6e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ10951.1 - 7.4e-17 61.5 0.0 1.2e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ10951.1 - 1.8e-06 27.5 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ10951.1 - 0.0009 18.6 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl-CoA_dh_1 PF00441.24 OAJ10960.1 - 3.2e-31 108.6 0.2 5.1e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ10960.1 - 8.2e-17 61.2 0.2 1.8e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 OAJ10960.1 - 2.4e-16 59.6 0.0 5.9e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 OAJ10960.1 - 5.1e-15 56.1 0.2 7.3e-14 52.4 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ10960.1 - 1.1e-06 29.0 0.2 1.8e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 OAJ10968.1 - 2.7e-06 26.5 1.3 3.6e-06 26.2 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VPS13 PF16908.5 OAJ10969.1 - 3.1e-21 76.3 1.3 5e-21 75.6 0.1 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal DUF4085 PF13315.6 OAJ10969.1 - 0.0063 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4085) Chorein_N PF12624.7 OAJ10970.1 - 2.2e-33 114.8 0.0 4.7e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Fas_alpha_ACP PF18325.1 OAJ10970.1 - 3.4e-28 99.0 0.0 7.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain VPS13 PF16908.5 OAJ10970.1 - 8e-28 97.8 0.1 1.3e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal FAS_I_H PF18314.1 OAJ10970.1 - 1.1e-14 54.5 0.0 2.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain adh_short PF00106.25 OAJ10970.1 - 6.4e-08 32.3 0.5 0.0013 18.2 0.0 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ10970.1 - 4.3e-05 23.2 0.1 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ10970.1 - 0.00026 21.0 0.6 0.036 14.0 0.0 2.4 2 0 0 2 2 2 2 KR domain Flot PF15975.5 OAJ10980.1 - 0.081 13.1 3.5 0.1 12.8 3.5 1.1 1 0 0 1 1 1 0 Flotillin DUF1897 PF09005.10 OAJ10980.1 - 0.24 10.9 2.3 1.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) FYDLN_acid PF09538.10 OAJ10980.1 - 1.4 9.7 31.2 1.8 9.3 31.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 OAJ10980.1 - 1.7 8.9 16.6 1.9 8.8 16.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Serinc PF03348.15 OAJ10980.1 - 4.7 6.0 6.4 5.3 5.8 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFB6 PF17110.5 OAJ10980.1 - 5.4 6.7 14.0 6.1 6.6 14.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2796 PF10986.8 OAJ10980.1 - 6.3 6.7 11.5 7.1 6.6 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Cwf_Cwc_15 PF04889.12 OAJ10980.1 - 6.3 6.5 34.2 7.3 6.3 34.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ10980.1 - 9.3 5.5 32.3 12 5.1 32.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CCHC PF00098.23 OAJ10987.1 - 0.00015 21.7 1.5 0.00034 20.5 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ10987.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 OAJ10988.1 - 6.1e-70 235.6 0.0 8.3e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HHH_8 PF14716.6 OAJ10989.1 - 0.068 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DSS1_SEM1 PF05160.13 OAJ10997.1 - 4.9e-18 64.9 13.9 2.9e-17 62.5 13.9 1.9 1 1 0 1 1 1 1 DSS1/SEM1 family PAC1 PF16094.5 OAJ10998.1 - 6.4 5.9 6.1 1.7 7.8 2.1 1.9 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Myb_DNA-binding PF00249.31 OAJ10999.1 - 2.9e-11 43.4 0.0 9.7e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 OAJ10999.1 - 9.9e-11 41.8 0.0 4.8e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 OAJ10999.1 - 1.3e-08 34.5 5.4 2.1e-08 33.8 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OAJ10999.1 - 1.8e-06 28.1 0.0 5.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Herpes_UL25 PF01499.16 OAJ11008.1 - 0.076 11.5 0.4 0.089 11.3 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family RAP1 PF07218.11 OAJ11008.1 - 0.65 8.2 5.4 0.66 8.2 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YL1 PF05764.13 OAJ11009.1 - 3.3e-05 24.1 7.9 4.5e-05 23.7 7.9 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAJ11009.1 - 0.00051 18.5 5.6 0.00051 18.5 5.6 1.1 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 OAJ11009.1 - 0.0012 19.1 9.9 0.0015 18.8 9.9 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Spt5_N PF11942.8 OAJ11009.1 - 0.077 14.0 16.0 0.14 13.2 16.0 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Lin-8 PF03353.15 OAJ11009.1 - 0.29 10.7 15.0 0.34 10.4 15.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 OAJ11009.1 - 0.33 10.4 6.2 0.46 9.9 6.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 OAJ11009.1 - 0.43 9.3 10.9 0.41 9.4 10.9 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 OAJ11009.1 - 0.66 8.9 10.7 0.83 8.6 10.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.9 OAJ11009.1 - 0.73 8.6 8.4 0.82 8.5 8.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plasmodium_Vir PF05795.11 OAJ11009.1 - 1.4 8.3 5.8 1.5 8.2 5.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLC12 PF03522.15 OAJ11009.1 - 1.5 7.7 6.0 1.6 7.6 6.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 OAJ11009.1 - 2 6.8 6.0 2.2 6.6 6.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 CPSF100_C PF13299.6 OAJ11009.1 - 2.3 8.4 7.6 4.1 7.5 7.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Rrn6 PF10214.9 OAJ11009.1 - 2.4 6.5 21.2 3 6.2 21.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Roughex PF06020.11 OAJ11009.1 - 3.5 6.6 14.4 5.2 6.1 14.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Connexin PF00029.19 OAJ11009.1 - 4 7.1 5.1 5.1 6.8 5.1 1.2 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 OAJ11009.1 - 4.4 5.4 19.5 4.9 5.3 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.8 OAJ11009.1 - 5.3 5.8 10.6 6.7 5.5 10.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt20 PF12090.8 OAJ11009.1 - 5.5 6.5 24.9 7.3 6.1 24.9 1.1 1 0 0 1 1 1 0 Spt20 family Hid1 PF12722.7 OAJ11009.1 - 6.9 4.7 11.3 7 4.6 11.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VID27 PF08553.10 OAJ11010.1 - 4.6e-12 45.7 0.5 3e-05 23.3 0.1 2.1 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain NYAP_N PF15439.6 OAJ11010.1 - 0.67 9.1 2.7 0.82 8.8 2.7 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF2066 PF09839.9 OAJ11020.1 - 0.19 11.1 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) RVT_1 PF00078.27 OAJ11031.1 - 3.3e-23 82.4 0.0 5.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11031.1 - 7.1e-23 80.5 0.0 1.8e-14 53.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11031.1 - 4.8e-18 65.4 0.0 2.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11031.1 - 2.7e-15 56.2 0.1 5e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11031.1 - 7.1e-09 35.9 0.0 1.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ11031.1 - 9.8e-05 22.9 0.1 0.00041 20.9 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11031.1 - 0.015 15.9 0.0 0.037 14.6 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ11031.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease MTP18 PF10558.9 OAJ11041.1 - 6.9e-30 104.2 0.1 1.2e-29 103.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF3464 PF11947.8 OAJ11041.1 - 2.4 7.9 5.1 0.34 10.7 0.2 1.9 2 1 0 2 2 2 0 Photosynthesis affected mutant 68 Blt1 PF12754.7 OAJ11052.1 - 0.13 12.6 1.1 0.37 11.1 1.1 1.8 1 1 0 1 1 1 0 Blt1 N-terminal domain Adeno_PIX PF03955.14 OAJ11052.1 - 3.6 7.8 11.8 5.8 7.1 11.8 1.3 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) MULE PF10551.9 OAJ11053.1 - 1.6e-08 34.9 0.2 6.6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 MULE transposase domain DDE_Tnp_IS240 PF13610.6 OAJ11053.1 - 0.015 15.5 0.1 2.1 8.5 0.1 2.8 1 1 0 1 1 1 0 DDE domain DUF3845 PF12956.7 OAJ11053.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure CRISPR_Cas9_WED PF18061.1 OAJ11053.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain Septin PF00735.18 OAJ11054.1 - 1.3e-08 34.4 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Septin Sugar_tr PF00083.24 OAJ11060.1 - 7.9e-102 341.4 18.3 9.5e-102 341.2 18.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ11060.1 - 2.7e-24 85.8 25.3 2.4e-23 82.7 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FYDLN_acid PF09538.10 OAJ11060.1 - 0.067 13.9 0.6 0.067 13.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Dimer_Tnp_hAT PF05699.14 OAJ11070.1 - 3.8e-06 26.6 0.0 1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DEAD PF00270.29 OAJ11079.1 - 3.7e-08 33.3 0.0 7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ11079.1 - 1.7e-07 31.6 0.0 1.2e-06 28.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ11079.1 - 0.00092 19.3 0.0 0.0022 18.0 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ11079.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 OAJ11079.1 - 0.29 11.2 1.5 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain DUF2286 PF10051.9 OAJ11081.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) MitMem_reg PF13012.6 OAJ11089.1 - 8.9e-35 119.5 0.1 1.5e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 OAJ11089.1 - 1.3e-29 102.6 0.0 2.1e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.25 OAJ11090.1 - 2.4e-61 207.4 0.0 3.2e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ11090.1 - 2.8e-31 108.7 0.0 3.7e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ11090.1 - 0.0077 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ11090.1 - 0.076 12.9 0.0 0.28 11.0 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 OAJ11098.1 - 1.5e-14 53.8 0.0 2.9e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ11098.1 - 2.4e-12 46.7 0.0 6.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11098.1 - 1.6e-11 44.5 0.0 3.8e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ11098.1 - 7.3e-11 42.0 0.0 6.3e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ11098.1 - 0.018 15.3 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ11098.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger Myb_DNA-bind_3 PF12776.7 OAJ11099.1 - 4.4e-06 27.6 0.2 8.5e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myc_N PF01056.18 OAJ11099.1 - 0.015 15.2 1.2 0.018 15.0 1.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF4611 PF15387.6 OAJ11099.1 - 0.017 15.3 5.9 0.04 14.1 5.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF913 PF06025.12 OAJ11099.1 - 0.15 11.0 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-B_dimeris PF09026.10 OAJ11099.1 - 0.26 11.7 8.3 0.46 10.9 8.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Trypan_PARP PF05887.11 OAJ11099.1 - 0.56 10.2 3.9 0.85 9.6 3.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.12 OAJ11099.1 - 2.5 7.3 8.0 3.3 7.0 8.0 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ11099.1 - 7.9 4.4 10.2 9.5 4.2 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi p450 PF00067.22 OAJ11106.1 - 3.7e-13 49.1 0.0 9.3e-13 47.7 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 An_peroxidase PF03098.15 OAJ11106.1 - 1.8e-08 33.5 0.0 2.5e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase GMC_oxred_N PF00732.19 OAJ11107.1 - 8.9e-62 209.1 0.0 1.3e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ11107.1 - 3e-27 95.9 0.0 7e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ11107.1 - 7.3e-06 25.3 0.1 0.00088 18.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ11107.1 - 1.8e-05 24.9 0.1 7.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ11107.1 - 0.00018 21.2 2.2 0.00098 18.8 2.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ11107.1 - 0.00023 20.4 0.2 0.00034 19.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAJ11107.1 - 0.00059 19.2 0.8 0.13 11.5 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ11107.1 - 0.00096 18.0 0.5 0.0051 15.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 OAJ11107.1 - 0.0034 16.7 0.2 0.011 15.0 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ11107.1 - 0.047 12.9 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SURF4 PF02077.15 OAJ11115.1 - 5.4e-95 318.0 3.2 6.2e-95 317.8 3.2 1.0 1 0 0 1 1 1 1 SURF4 family DUF5562 PF17717.1 OAJ11115.1 - 0.0076 16.2 0.9 0.014 15.4 0.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5562) Citrate_bind PF16114.5 OAJ11116.1 - 2.8e-89 297.3 0.1 5.9e-89 296.3 0.1 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 OAJ11116.1 - 2.9e-20 72.6 0.1 1.7e-17 63.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 OAJ11116.1 - 2.2e-14 53.5 0.1 6e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 OAJ11116.1 - 7.8e-12 45.7 0.0 2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 OAJ11116.1 - 1.2e-06 28.3 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 OAJ11116.1 - 5.9e-05 22.9 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_5 PF13549.6 OAJ11116.1 - 0.031 13.7 0.0 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain HTH_32 PF13565.6 OAJ11127.1 - 0.073 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain TerB PF05099.13 OAJ11127.1 - 0.21 11.6 0.0 0.29 11.1 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB SurE PF01975.17 OAJ11137.1 - 8.6e-33 113.8 2.3 1.4e-32 113.0 0.1 2.1 1 1 1 2 2 2 1 Survival protein SurE ABC2_membrane PF01061.24 OAJ11138.1 - 1.8e-78 262.8 58.5 5.9e-42 143.5 24.2 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ11138.1 - 3.6e-39 134.4 0.0 9.6e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ11138.1 - 7.2e-22 77.1 5.2 3e-19 68.7 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter AAA_33 PF13671.6 OAJ11138.1 - 2.7e-06 27.6 0.9 0.094 12.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 OAJ11138.1 - 3.8e-06 26.5 0.0 0.00055 19.4 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ11138.1 - 2.7e-05 24.2 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ11138.1 - 3.1e-05 23.6 0.7 0.019 14.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ11138.1 - 0.0004 20.3 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAJ11138.1 - 0.0004 20.9 3.4 0.033 14.7 0.0 3.9 5 0 0 5 5 4 1 AAA domain ABC2_membrane_3 PF12698.7 OAJ11138.1 - 0.00049 19.3 20.0 0.00049 19.3 20.0 3.4 3 1 0 3 3 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 OAJ11138.1 - 0.00056 19.5 0.1 0.0055 16.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 OAJ11138.1 - 0.00066 20.2 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAJ11138.1 - 0.0011 19.3 0.1 0.16 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ11138.1 - 0.0013 19.0 0.0 0.95 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 OAJ11138.1 - 0.0044 16.6 0.1 0.28 10.8 0.0 2.7 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 OAJ11138.1 - 0.0097 15.6 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ11138.1 - 0.019 15.0 0.1 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 OAJ11138.1 - 0.021 14.1 0.2 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OAJ11138.1 - 0.039 13.9 0.4 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 OAJ11138.1 - 0.076 13.2 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Cas_Csy1 PF09611.10 OAJ11138.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) RNA_helicase PF00910.22 OAJ11138.1 - 0.14 12.6 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 OAJ11138.1 - 0.16 12.5 0.6 0.5 10.8 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 OAJ11138.1 - 0.18 12.2 0.1 30 5.0 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OAJ11138.1 - 1.2 9.5 3.8 1.3 9.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain zf-CCHC PF00098.23 OAJ11147.1 - 1.3e-05 25.0 0.6 2.1e-05 24.4 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ11147.1 - 0.00063 19.5 1.0 0.001 18.9 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle Yae1_N PF09811.9 OAJ11147.1 - 0.042 13.5 1.2 0.097 12.4 1.2 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Sugarporin_N PF11471.8 OAJ11147.1 - 1.7 8.7 5.1 0.21 11.6 0.3 2.0 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension TEBP_beta PF07404.11 OAJ11148.1 - 0.14 11.5 4.5 0.25 10.7 4.5 1.3 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) Atg14 PF10186.9 OAJ11148.1 - 0.25 10.4 17.2 0.032 13.3 9.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 OAJ11148.1 - 0.27 11.9 12.3 2.9 8.6 0.0 3.6 3 0 0 3 3 3 0 SlyX BRE1 PF08647.11 OAJ11148.1 - 0.28 11.3 17.5 0.047 13.8 2.2 3.0 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase NPV_P10 PF05531.12 OAJ11148.1 - 0.35 11.3 3.8 3 8.4 0.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 OAJ11148.1 - 1.5 8.2 19.1 3.2 7.1 12.7 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HALZ PF02183.18 OAJ11148.1 - 2 8.7 4.6 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Med9 PF07544.13 OAJ11148.1 - 2.4 8.3 6.3 21 5.3 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.20 OAJ11148.1 - 2.5 8.1 12.8 7.7 6.5 1.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit DivIC PF04977.15 OAJ11148.1 - 2.7 7.8 20.4 0.29 10.9 0.6 3.3 3 0 0 3 3 3 0 Septum formation initiator UPF0242 PF06785.11 OAJ11148.1 - 3.2 7.8 16.3 2 8.5 9.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 OAJ11148.1 - 3.4 8.2 30.2 1.3 9.5 2.4 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region She9_MDM33 PF05546.11 OAJ11148.1 - 3.7 7.3 12.7 0.98 9.2 0.3 2.4 2 0 0 2 2 2 0 She9 / Mdm33 family TolA_bind_tri PF16331.5 OAJ11148.1 - 4.8 7.3 17.3 2 8.6 0.3 3.3 2 1 1 3 3 3 0 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 OAJ11148.1 - 5 7.2 19.1 1.5 8.9 1.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SPATA1_C PF15743.5 OAJ11148.1 - 5.4 7.1 12.4 0.48 10.5 0.3 2.8 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus Latarcin PF10279.9 OAJ11148.1 - 5.7 7.4 7.0 5.7 7.4 0.4 2.5 2 0 0 2 2 2 0 Latarcin precursor MscS_porin PF12795.7 OAJ11148.1 - 6.6 6.2 30.0 0.47 10.0 19.6 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FH2 PF02181.23 OAJ11148.1 - 9.1 5.3 9.3 0.27 10.3 1.3 2.2 2 1 0 3 3 3 0 Formin Homology 2 Domain V_ATPase_I PF01496.19 OAJ11148.1 - 9.3 4.0 7.9 6.2 4.6 4.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 OAJ11148.1 - 9.3 6.6 24.6 0.13 12.6 1.2 3.3 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Transposase_21 PF02992.14 OAJ11160.1 - 0.00048 19.4 0.0 0.00081 18.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2H2_2 PF12756.7 OAJ11160.1 - 0.13 12.6 0.5 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) cwf21 PF08312.12 OAJ11160.1 - 0.21 11.8 5.2 2.7 8.2 0.5 2.8 2 0 0 2 2 2 0 cwf21 domain zf-C2H2_2 PF12756.7 OAJ11161.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Mito_carr PF00153.27 OAJ11171.1 - 8.6e-65 214.7 5.0 2.3e-24 85.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 OAJ11171.1 - 0.16 11.1 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 Fuseless NMO PF03060.15 OAJ11172.1 - 3.6e-51 174.5 3.2 5.2e-51 174.0 3.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAJ11172.1 - 1.9e-07 30.4 6.5 1.3e-06 27.7 6.5 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAJ11172.1 - 0.00017 20.7 2.7 0.00033 19.8 2.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IF2_N PF04760.15 OAJ11172.1 - 0.036 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Tim17 PF02466.19 OAJ11173.1 - 9.4e-09 35.6 10.4 1.5e-08 35.0 10.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FAA_hydrolase PF01557.18 OAJ11174.1 - 1.8e-56 191.2 0.0 2.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HRCT1 PF15758.5 OAJ11188.1 - 0.047 14.6 0.0 0.097 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 DUF4218 PF13960.6 OAJ11189.1 - 0.19 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) PIF1 PF05970.14 OAJ11206.1 - 1.9e-21 76.7 0.0 4.4e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ11206.1 - 1.1e-15 57.9 1.5 3.1e-15 56.4 0.0 2.5 2 1 1 3 3 3 1 AAA domain Helitron_like_N PF14214.6 OAJ11206.1 - 2e-15 57.5 0.0 5.3e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_19 PF13245.6 OAJ11206.1 - 5.6e-09 36.5 0.3 2.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ11206.1 - 0.0012 19.2 0.9 0.0055 17.1 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ11206.1 - 0.092 12.7 0.4 1.7 8.7 0.1 3.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 OAJ11206.1 - 0.12 12.1 0.1 22 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 OAJ11206.1 - 0.12 12.0 0.0 0.47 10.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 OAJ11206.1 - 0.18 11.9 0.0 0.57 10.3 0.0 1.8 1 0 0 1 1 1 0 Torsin DDE_1 PF03184.19 OAJ11213.1 - 4.8e-19 68.7 0.4 1e-18 67.6 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ11213.1 - 4e-09 36.4 0.3 8.8e-08 32.1 0.0 2.9 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain CRAL_TRIO_N PF03765.15 OAJ11228.1 - 4.1e-13 49.3 1.2 8.2e-13 48.3 1.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TelA PF05816.11 OAJ11228.1 - 0.0045 16.1 0.2 0.008 15.3 0.1 1.4 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) DNA_pol_A_exoN PF18305.1 OAJ11228.1 - 0.021 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain adh_short PF00106.25 OAJ11234.1 - 8e-41 139.6 0.1 1.1e-40 139.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11234.1 - 2.4e-21 76.4 0.0 3.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ11234.1 - 0.00018 21.5 0.0 0.00036 20.5 0.0 1.5 1 1 0 1 1 1 1 KR domain MASE2 PF05230.11 OAJ11235.1 - 0.022 14.8 0.3 0.022 14.8 0.3 1.8 2 0 0 2 2 2 0 MASE2 domain DUF2651 PF10852.8 OAJ11235.1 - 1.7 9.3 14.3 0.15 12.7 2.8 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2651) DUF1768 PF08719.11 OAJ11236.1 - 5.9e-09 36.4 1.4 9.2e-09 35.7 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UPF0167 PF03691.14 OAJ11236.1 - 0.078 12.8 0.4 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) PPR_2 PF13041.6 OAJ11245.1 - 6.8e-27 93.4 0.0 2.2e-06 27.7 0.0 9.1 8 1 1 9 9 9 4 PPR repeat family PPR PF01535.20 OAJ11245.1 - 8e-21 72.8 7.8 0.028 14.7 0.0 11.5 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 OAJ11245.1 - 5.6e-11 42.4 0.0 0.0029 17.6 0.0 6.0 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAJ11245.1 - 2.5e-10 39.9 0.0 14 5.5 0.0 8.9 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 OAJ11245.1 - 5.3e-06 25.9 1.4 0.0014 18.0 0.1 3.5 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAJ11245.1 - 0.21 12.5 0.1 0.21 12.5 0.1 8.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ11245.1 - 0.49 10.9 7.7 0.58 10.7 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DLIC PF05783.11 OAJ11246.1 - 3e-43 148.4 9.3 6.1e-30 104.5 1.0 5.9 4 2 0 4 4 4 4 Dynein light intermediate chain (DLIC) MCM PF00493.23 OAJ11246.1 - 7.8e-05 21.9 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 OAJ11246.1 - 0.00037 20.9 0.5 0.0037 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 OAJ11246.1 - 0.0059 16.2 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ11246.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 OAJ11246.1 - 0.083 13.1 1.3 0.13 12.5 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ11246.1 - 0.086 12.6 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cellulase PF00150.18 OAJ11255.1 - 8.9e-13 48.3 8.9 2.6e-12 46.8 8.9 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) V-SNARE_C PF12352.8 OAJ11256.1 - 3.3e-13 49.7 0.3 7.7e-13 48.5 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ11256.1 - 4.5e-06 26.5 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Sec20 RVT_1 PF00078.27 OAJ11257.1 - 5.3e-30 104.6 0.0 7.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GTP_EFTU PF00009.27 OAJ11266.1 - 6.5e-28 97.6 0.5 2.5e-21 76.1 1.9 3.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAJ11266.1 - 7.4e-22 77.5 0.0 1.4e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 OAJ11266.1 - 1.7e-06 28.1 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 OAJ11266.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 OAJ11266.1 - 0.0065 15.9 0.0 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 OAJ11266.1 - 0.32 11.4 3.5 3.1 8.3 0.1 2.9 2 0 0 2 2 2 0 Elongation factor Tu domain 2 HLH PF00010.26 OAJ11267.1 - 4.6e-10 39.3 0.1 8.8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MCC-bdg_PDZ PF10506.9 OAJ11267.1 - 0.002 18.1 0.7 0.0071 16.3 0.7 2.0 1 0 0 1 1 1 1 PDZ domain of MCC-2 bdg protein for Usher syndrome UcrQ PF02939.16 OAJ11278.1 - 4e-26 90.8 4.1 4.9e-26 90.5 4.1 1.1 1 0 0 1 1 1 1 UcrQ family UQ_con PF00179.26 OAJ11279.1 - 2.3e-22 79.1 0.0 2.8e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MCM PF00493.23 OAJ11292.1 - 2.1e-100 334.4 0.0 2.9e-100 334.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ11292.1 - 9.5e-38 128.9 0.0 1.6e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 OAJ11292.1 - 2.7e-33 115.4 24.3 2.7e-33 115.4 24.3 3.0 3 1 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 OAJ11292.1 - 6.6e-26 90.6 0.3 2.5e-25 88.7 0.3 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ11292.1 - 5.7e-13 49.4 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ11292.1 - 2.4e-08 33.6 0.0 9e-07 28.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ11292.1 - 3.9e-06 26.9 0.0 8.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ11292.1 - 0.00033 20.5 0.0 0.003 17.4 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ11292.1 - 0.019 14.7 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DNA_gyraseB_C PF00986.21 OAJ11292.1 - 0.038 14.2 0.5 2.5 8.3 0.0 3.1 3 0 0 3 3 3 0 DNA gyrase B subunit, carboxyl terminus AAA_lid_2 PF17863.1 OAJ11292.1 - 0.041 13.7 1.6 0.079 12.8 0.1 2.3 2 0 0 2 2 2 0 AAA lid domain Zn_ribbon_2 PF12674.7 OAJ11292.1 - 0.049 14.3 0.2 0.12 13.0 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA PF00004.29 OAJ11292.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 OAJ11293.1 - 1.9e-43 148.7 0.0 1.8e-15 57.0 0.0 4.6 5 0 0 5 5 5 4 Septin TFIIA PF03153.13 OAJ11293.1 - 0.00014 22.0 16.6 0.00014 22.0 16.6 3.2 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.23 OAJ11293.1 - 0.066 13.3 0.0 0.48 10.5 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 OAJ11293.1 - 0.086 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein BUD22 PF09073.10 OAJ11293.1 - 0.14 11.4 42.6 1.1 8.5 29.9 2.5 2 0 0 2 2 2 0 BUD22 Nop25 PF09805.9 OAJ11293.1 - 0.24 11.9 40.8 0.072 13.6 32.2 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 OAJ11293.1 - 1.3 7.1 48.6 0.23 9.5 32.2 2.1 2 0 0 2 2 2 0 DNA polymerase phi rve PF00665.26 OAJ11301.1 - 6.5e-14 52.1 0.0 8.8e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain C1q PF00386.21 OAJ11301.1 - 0.24 11.6 0.0 0.42 10.8 0.0 1.3 1 0 0 1 1 1 0 C1q domain RT_RNaseH_2 PF17919.1 OAJ11302.1 - 1.8e-12 47.2 0.0 2.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11302.1 - 0.0032 17.7 0.0 0.0052 17.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase FHA PF00498.26 OAJ11303.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 FHA domain RVT_1 PF00078.27 OAJ11308.1 - 1.3e-24 87.0 0.0 2.3e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11308.1 - 3e-23 81.7 0.1 4.1e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11308.1 - 7.3e-18 64.8 0.0 1.3e-11 44.7 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11308.1 - 2.8e-16 59.4 0.0 5.5e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11308.1 - 3.9e-09 36.7 0.0 9.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ11308.1 - 2.7e-05 24.7 0.1 7.9e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OAJ11308.1 - 0.0026 18.1 0.0 0.0081 16.5 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ11308.1 - 0.0047 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.17 OAJ11308.1 - 0.006 16.8 0.4 0.016 15.5 0.4 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein YjbT PF17089.5 OAJ11308.1 - 0.018 15.1 0.4 0.095 12.7 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family Dus PF01207.17 OAJ11318.1 - 2.2e-44 151.8 0.0 8.7e-25 87.4 0.0 3.0 3 0 0 3 3 3 3 Dihydrouridine synthase (Dus) Mito_carr PF00153.27 OAJ11319.1 - 6.6e-71 234.3 0.9 1.4e-24 85.8 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIE-A_C PF11521.8 OAJ11319.1 - 0.21 11.9 1.2 0.42 11.0 1.2 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha PGA2 PF07543.12 OAJ11319.1 - 1.3 9.0 3.0 1.2 9.2 1.6 1.6 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L14 PF00238.19 OAJ11320.1 - 4.1e-43 146.3 1.1 4.7e-43 146.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RRM_1 PF00076.22 OAJ11330.1 - 2.1e-46 155.6 0.0 4e-22 77.8 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ11330.1 - 1.2e-08 34.6 0.0 0.0016 18.0 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ11330.1 - 1.7e-08 34.4 0.0 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 OAJ11330.1 - 1.5e-06 28.2 2.6 0.022 14.8 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_occluded PF16842.5 OAJ11330.1 - 0.00017 21.3 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 OAJ11330.1 - 0.0019 18.2 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Bud13 PF09736.9 OAJ11331.1 - 6.3e-09 36.4 7.8 6.3e-09 36.4 7.8 2.6 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF3350 PF11830.8 OAJ11331.1 - 0.091 13.1 5.9 5.1 7.5 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) RRM_1 PF00076.22 OAJ11332.1 - 5.4e-44 147.9 0.0 2.9e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ11332.1 - 3.4e-09 36.7 0.0 0.00028 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 OAJ11332.1 - 1.3e-05 24.7 0.0 0.00091 18.8 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ11332.1 - 2.2e-05 24.2 0.0 0.009 15.9 0.0 2.6 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAJ11332.1 - 5.5e-05 23.2 0.0 0.45 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ11332.1 - 0.00028 20.8 0.0 0.4 10.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 OAJ11332.1 - 0.18 11.5 0.0 4.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated NTPase_P4 PF11602.8 OAJ11333.1 - 0.15 11.2 1.1 0.17 11.1 1.1 1.0 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 SNAP PF14938.6 OAJ11334.1 - 2.2e-94 316.0 12.4 2.5e-94 315.9 12.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 OAJ11334.1 - 0.0032 17.6 1.6 4.4 7.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ11334.1 - 0.0055 17.3 19.2 12 6.8 0.2 6.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ11334.1 - 0.0074 16.9 2.5 0.0074 16.9 2.5 5.4 2 1 4 6 6 6 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 OAJ11334.1 - 0.015 14.4 3.4 0.31 10.1 0.6 2.2 1 1 0 2 2 2 0 Spatacsin C-terminus PerC PF06069.11 OAJ11334.1 - 0.033 14.5 0.7 2.2 8.6 0.1 2.6 2 1 1 3 3 3 0 PerC transcriptional activator DUF4170 PF13773.6 OAJ11334.1 - 0.25 11.5 0.0 0.25 11.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) TPR_2 PF07719.17 OAJ11334.1 - 0.57 10.4 20.4 7.4 7.0 0.1 7.0 3 3 6 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ11334.1 - 2.1 8.3 17.6 4.2 7.4 0.1 6.7 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ11334.1 - 6.7 7.2 10.8 28 5.3 0.1 5.7 4 2 3 8 8 8 0 Tetratricopeptide repeat Zip PF02535.22 OAJ11342.1 - 9.7e-40 136.8 16.3 9.7e-40 136.8 16.3 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter TMA7 PF09072.10 OAJ11352.1 - 0.64 10.9 5.0 2.2 9.2 5.0 1.9 1 0 0 1 1 1 0 Translation machinery associated TMA7 LigB PF02900.18 OAJ11353.1 - 1.2e-22 80.3 0.1 9.3e-16 57.7 0.1 2.1 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Mrr_cat PF04471.12 OAJ11353.1 - 0.037 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease DUF2959 PF11172.8 OAJ11362.1 - 0.014 15.5 0.4 0.017 15.3 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Cutinase PF01083.22 OAJ11367.1 - 7.6e-22 78.1 0.0 1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase DUF726 PF05277.12 OAJ11367.1 - 0.79 8.6 0.0 0.79 8.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF726) DUF5548 PF17702.1 OAJ11369.1 - 0.023 14.5 1.1 0.047 13.4 0.5 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5548) Mitofilin PF09731.9 OAJ11379.1 - 2.2e-64 218.4 51.9 1.1e-61 209.5 51.9 3.9 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF842 PF05811.13 OAJ11379.1 - 5.6 6.7 13.2 2.2 8.0 1.3 2.8 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Abhydrolase_8 PF06259.12 OAJ11380.1 - 0.033 13.8 0.0 2.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase Peptidase_M17_N PF02789.17 OAJ11380.1 - 0.075 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain NTF2 PF02136.20 OAJ11387.1 - 0.015 15.9 0.0 0.36 11.4 0.0 2.7 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 OAJ11387.1 - 0.069 13.1 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 IATP PF04568.12 OAJ11387.1 - 0.72 10.3 2.8 1.2 9.6 1.9 1.8 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF1752 PF08550.10 OAJ11388.1 - 3.2e-11 42.9 4.7 7.3e-11 41.7 4.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GTP_EFTU PF00009.27 OAJ11410.1 - 1.9e-56 190.7 0.4 3e-56 190.0 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ11410.1 - 1.7e-29 102.4 0.0 3.3e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ11410.1 - 2.3e-16 59.9 3.5 2.3e-16 59.9 3.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ11410.1 - 1.9e-05 24.7 0.1 4.3e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ11410.1 - 0.006 16.5 0.2 0.019 14.8 0.1 1.7 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 OAJ11410.1 - 0.015 14.9 0.5 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAJ11410.1 - 0.057 13.2 0.7 13 5.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zn_clus PF00172.18 OAJ11411.1 - 1.6e-08 34.5 10.4 2.4e-08 34.0 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim54 PF11711.8 OAJ11412.1 - 1.1e-38 133.0 0.0 1.8e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Vault_2 PF17794.1 OAJ11412.1 - 7.4 7.0 5.2 8.6 6.8 0.0 3.2 4 1 0 4 4 4 0 Major Vault Protein repeat domain adh_short PF00106.25 OAJ11413.1 - 5.4e-06 26.0 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ11413.1 - 0.0053 16.3 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 OAJ11413.1 - 0.036 13.4 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NinB PF05772.12 OAJ11413.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 NinB protein AlaDh_PNT_N PF05222.15 OAJ11422.1 - 3.5e-28 98.6 0.0 5.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain ThiC-associated PF13667.6 OAJ11422.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 ThiC-associated domain Cyclin_N PF00134.23 OAJ11423.1 - 0.014 15.1 0.1 0.014 15.1 0.1 2.8 4 0 0 4 4 4 0 Cyclin, N-terminal domain DUF2722 PF10846.8 OAJ11423.1 - 6.5 5.6 18.1 0.29 10.0 11.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) ABATE PF07336.11 OAJ11440.1 - 7.1 7.3 12.9 72 4.1 12.9 2.4 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Ku PF02735.16 OAJ11441.1 - 4.2e-32 111.5 0.0 2.8e-28 99.1 0.0 2.5 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 OAJ11441.1 - 8.7e-14 51.8 0.0 2e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 OAJ11441.1 - 1.1e-07 31.4 0.4 2.6e-07 30.2 0.2 1.7 2 0 0 2 2 2 1 SAP domain Ku_C PF03730.14 OAJ11441.1 - 0.00038 21.1 5.6 0.0034 18.1 0.1 3.4 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Nop53 PF07767.11 OAJ11441.1 - 0.0074 15.7 2.3 0.015 14.7 2.3 1.4 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PDE6_gamma PF04868.12 OAJ11441.1 - 0.047 13.9 0.1 0.19 12.0 0.1 2.0 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Spt5_N PF11942.8 OAJ11441.1 - 0.052 14.5 8.7 0.059 14.4 6.8 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BNIP2 PF12496.8 OAJ11441.1 - 0.2 12.1 4.3 0.2 12.1 2.7 1.8 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Cwf_Cwc_15 PF04889.12 OAJ11441.1 - 0.25 11.0 6.1 0.44 10.2 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med4 PF10018.9 OAJ11442.1 - 1.8e-15 57.1 3.1 2.7e-15 56.6 3.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CBFD_NFYB_HMF PF00808.23 OAJ11443.1 - 5.6e-13 49.0 0.5 1e-12 48.1 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1180 PF06679.12 OAJ11443.1 - 0.0021 18.5 1.7 0.0021 18.5 1.7 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1180) SPX PF03105.19 OAJ11443.1 - 0.18 11.7 8.0 0.26 11.2 8.0 1.2 1 0 0 1 1 1 0 SPX domain Spt20 PF12090.8 OAJ11443.1 - 0.23 11.0 10.5 0.34 10.5 10.5 1.3 1 0 0 1 1 1 0 Spt20 family KAR9 PF08580.10 OAJ11443.1 - 0.56 8.7 3.6 0.62 8.5 3.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SAGA-Tad1 PF12767.7 OAJ11443.1 - 0.59 9.8 3.9 2.3 7.9 3.9 1.9 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Histone PF00125.24 OAJ11443.1 - 1.5 9.2 14.5 7.3 7.0 12.6 2.6 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SOG2 PF10428.9 OAJ11443.1 - 2 7.5 6.5 2.5 7.2 6.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 OAJ11443.1 - 3 6.4 5.0 3.2 6.3 5.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Thioredoxin PF00085.20 OAJ11454.1 - 1.7e-60 201.4 0.2 3.5e-26 91.2 0.0 4.4 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 OAJ11454.1 - 3.9e-40 137.7 0.2 2.4e-34 118.9 0.2 3.4 3 1 1 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 OAJ11454.1 - 2.7e-14 53.0 0.1 6.4e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 OAJ11454.1 - 3.7e-11 43.5 2.6 0.044 14.2 0.1 4.6 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ11454.1 - 1.4e-10 41.4 0.1 0.16 12.3 0.0 4.5 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ11454.1 - 2.3e-07 30.9 0.1 0.027 14.7 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 OAJ11454.1 - 4.4e-06 26.6 1.4 0.029 14.3 0.0 3.2 4 0 0 4 4 4 2 AhpC/TSA family OST3_OST6 PF04756.13 OAJ11454.1 - 5.3e-06 26.0 0.1 2.1 7.6 0.0 3.9 1 1 2 4 4 4 3 OST3 / OST6 family, transporter family Redoxin PF08534.10 OAJ11454.1 - 0.00098 18.9 0.9 4.8 6.9 0.0 3.5 3 0 0 3 3 3 1 Redoxin ERp29_N PF07912.13 OAJ11454.1 - 0.013 15.6 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 OAJ11454.1 - 0.021 15.0 3.2 1.4 9.0 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 OAJ11454.1 - 0.031 14.0 0.7 18 5.0 0.0 3.7 3 1 1 4 4 4 0 Thioredoxin TraF PF13728.6 OAJ11454.1 - 0.039 13.8 2.9 3 7.6 0.0 3.5 4 0 0 4 4 3 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 OAJ11454.1 - 0.059 13.6 0.7 17 5.7 0.0 3.9 4 1 0 4 4 4 0 Glutaredoxin Pan3_PK PF18101.1 OAJ11455.1 - 6.9e-57 191.3 0.0 1.3e-56 190.4 0.0 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 OAJ11455.1 - 0.0079 15.6 0.0 0.021 14.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain DHHC PF01529.20 OAJ11464.1 - 1.1e-38 132.3 3.2 1.1e-38 132.3 3.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2569 PF10754.9 OAJ11464.1 - 0.032 14.7 4.6 2.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) POM121 PF15229.6 OAJ11464.1 - 1.9 8.1 9.9 3.3 7.3 9.9 1.3 1 0 0 1 1 1 0 POM121 family COX17 PF05051.13 OAJ11465.1 - 1.9e-20 73.0 5.0 2.4e-20 72.6 5.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) MdcG PF10620.9 OAJ11480.1 - 0.074 12.8 0.1 0.32 10.8 0.0 1.8 1 1 1 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG NDUF_B7 PF05676.13 OAJ11487.1 - 0.12 12.2 2.5 0.26 11.0 2.5 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) RT_RNaseH_2 PF17919.1 OAJ11488.1 - 6.9e-20 70.9 0.0 3.8e-13 49.3 0.0 2.9 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ11488.1 - 3.7e-16 59.0 0.0 6.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ11488.1 - 2.6e-15 56.6 0.0 1.4e-08 34.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11488.1 - 7.7e-12 45.4 0.0 1.6e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 OAJ11488.1 - 0.0068 16.6 0.2 0.033 14.4 0.0 2.4 3 0 0 3 3 3 1 H2C2 zinc finger AAA PF00004.29 OAJ11508.1 - 7.5e-58 194.6 0.0 5.3e-45 153.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ11508.1 - 1.8e-08 34.9 0.5 0.0083 16.5 0.0 3.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 OAJ11508.1 - 8.8e-08 31.8 5.1 0.00055 19.7 1.1 3.2 3 0 0 3 3 3 2 AAA+ lid domain AAA_18 PF13238.6 OAJ11508.1 - 2.1e-05 25.1 0.0 0.036 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ11508.1 - 3.2e-05 23.9 0.1 0.034 14.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ11508.1 - 0.00034 20.4 0.0 0.0054 16.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 OAJ11508.1 - 0.00062 19.9 0.0 0.46 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ11508.1 - 0.00076 19.5 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 OAJ11508.1 - 0.00082 19.6 0.2 0.034 14.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.6 OAJ11508.1 - 0.0011 18.9 0.0 0.9 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 OAJ11508.1 - 0.0016 18.2 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 OAJ11508.1 - 0.0018 18.5 0.0 0.59 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ11508.1 - 0.0032 16.7 0.0 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 OAJ11508.1 - 0.0032 16.6 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAJ11508.1 - 0.0032 17.0 0.1 0.024 14.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 OAJ11508.1 - 0.0033 16.8 0.3 0.0068 15.8 0.0 1.5 2 0 0 2 2 1 1 KaiC Sigma54_activ_2 PF14532.6 OAJ11508.1 - 0.0062 16.7 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 OAJ11508.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 OAJ11508.1 - 0.0081 16.3 0.0 0.021 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 OAJ11508.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 OAJ11508.1 - 0.019 14.3 1.1 0.058 12.8 0.1 2.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAJ11508.1 - 0.023 14.2 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ11508.1 - 0.026 14.9 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ11508.1 - 0.028 14.4 1.5 4.2 7.2 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Vps4_C PF09336.10 OAJ11508.1 - 0.058 13.4 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 OAJ11508.1 - 0.059 13.2 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 OAJ11508.1 - 0.076 12.7 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 OAJ11508.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 OAJ11508.1 - 0.099 12.3 0.1 0.25 11.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 OAJ11508.1 - 0.2 11.5 0.0 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ11508.1 - 0.2 11.4 0.7 19 5.1 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 OAJ11508.1 - 0.21 10.7 0.0 6.4 5.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain CBM_21 PF03370.13 OAJ11517.1 - 2.3e-30 105.1 0.1 3.8e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 OAJ11517.1 - 3.1e-08 34.1 0.2 9e-08 32.6 0.2 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF3712 PF12505.8 OAJ11536.1 - 1.2e-24 87.0 0.3 5e-12 46.2 0.0 4.6 3 1 0 3 3 3 3 Protein of unknown function (DUF3712) RVT_1 PF00078.27 OAJ11549.1 - 1.6e-25 90.0 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4210 PF13915.6 OAJ11562.1 - 2.4e-22 79.3 0.1 6.2e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 OAJ11562.1 - 1.8e-12 47.2 0.0 3.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis adh_short PF00106.25 OAJ11562.1 - 5.3e-05 22.8 0.0 0.001 18.5 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase Aldose_epim PF01263.20 OAJ11563.1 - 6.2e-30 104.5 0.0 7.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Alg6_Alg8 PF03155.15 OAJ11564.1 - 0.0028 16.7 0.1 0.0035 16.4 0.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TMF_TATA_bd PF12325.8 OAJ11578.1 - 0.037 14.2 0.3 0.037 14.2 0.3 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Erf4 PF10256.9 OAJ11589.1 - 5.7e-31 107.0 0.0 6.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.21 OAJ11590.1 - 6.4e-66 222.4 0.1 8.5e-66 222.0 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 OAJ11590.1 - 9.5e-06 25.6 0.8 1.7e-05 24.8 0.4 1.6 1 1 1 2 2 2 1 Clathrin adaptor complex small chain MAM PF00629.23 OAJ11590.1 - 0.047 13.6 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu RNA_pol_Rpb5_C PF01191.19 OAJ11591.1 - 2.7e-32 110.5 0.0 6.2e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 OAJ11591.1 - 1.6e-26 92.7 0.1 1.6e-26 92.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 OAJ11591.1 - 2.4e-05 24.3 0.1 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease AP3D1 PF06375.11 OAJ11591.1 - 0.025 14.8 5.3 0.1 12.8 4.4 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PDT PF00800.18 OAJ11591.1 - 0.5 10.2 3.3 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Prephenate dehydratase Presenilin PF01080.17 OAJ11591.1 - 0.64 8.7 3.8 0.77 8.5 3.8 1.2 1 0 0 1 1 1 0 Presenilin CDT1_C PF16679.5 OAJ11591.1 - 3.4 8.2 9.5 43 4.6 8.3 3.0 2 1 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain RVT_2 PF07727.14 OAJ11604.1 - 1.9e-68 230.7 0.0 2.8e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ11604.1 - 3.2e-19 69.3 0.0 2.5e-18 66.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ11604.1 - 5.7e-07 29.3 0.1 5.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ11604.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ11604.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.8 OAJ11604.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 PPR_2 PF13041.6 OAJ11615.1 - 1.6e-13 50.6 0.0 0.0094 16.1 0.0 6.3 5 1 1 6 6 6 4 PPR repeat family PPR_1 PF12854.7 OAJ11615.1 - 1.2e-07 31.3 1.7 0.12 12.1 0.0 5.5 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 OAJ11615.1 - 1.7e-06 28.0 0.0 1 9.5 0.0 4.5 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 OAJ11615.1 - 7.3e-06 25.9 7.4 0.069 13.4 0.0 5.8 5 1 0 5 5 5 2 PPR repeat PPR_long PF17177.4 OAJ11615.1 - 0.00014 21.3 0.3 0.086 12.2 0.0 3.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP EIN3 PF04873.13 OAJ11615.1 - 0.0057 16.0 0.5 0.015 14.6 0.0 1.9 2 0 0 2 2 2 1 Ethylene insensitive 3 TPR_14 PF13428.6 OAJ11615.1 - 0.055 14.3 8.8 69 4.7 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 OAJ11628.1 - 1.1e-10 41.7 0.0 1.9e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OAJ11628.1 - 8.2e-07 29.4 0.0 0.065 13.7 0.0 2.6 1 1 1 2 2 2 2 MULE transposase domain SWIM PF04434.17 OAJ11628.1 - 0.018 14.7 0.4 0.044 13.5 0.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger Prok-JAB PF14464.6 OAJ11629.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PBP1_TM PF14812.6 OAJ11629.1 - 0.17 12.3 2.5 0.25 11.7 0.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Serine_rich PF08824.10 OAJ11640.1 - 0.086 12.8 0.6 0.34 10.9 0.1 2.1 2 1 1 3 3 3 0 Serine rich protein interaction domain MARVEL PF01284.23 OAJ11641.1 - 2.6e-07 30.8 16.8 4.1e-07 30.1 16.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain Wzy_C PF04932.15 OAJ11641.1 - 0.97 9.1 6.6 0.42 10.2 2.3 2.1 2 1 0 2 2 2 0 O-Antigen ligase DUF621 PF04789.15 OAJ11642.1 - 9.9 5.2 8.6 11 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF621) Zn_clus PF00172.18 OAJ11649.1 - 1.5 9.0 5.7 5.6 7.2 5.7 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_3 PF13456.6 OAJ11650.1 - 0.084 12.7 0.1 0.16 11.8 0.0 1.4 2 0 0 2 2 2 0 Reverse transcriptase-like FAM110_N PF14161.6 OAJ11651.1 - 0.037 14.2 0.5 0.04 14.1 0.5 1.2 1 0 0 1 1 1 0 Centrosome-associated N terminus RVT_2 PF07727.14 OAJ11661.1 - 3.3e-60 203.7 0.0 4.6e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ11661.1 - 0.11 12.3 6.1 0.12 12.1 2.4 2.8 4 1 0 4 4 4 0 Reverse transcriptase-like PQ-loop PF04193.14 OAJ11662.1 - 2.7e-13 49.5 0.1 6e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 PQ loop repeat DUF3435 PF11917.8 OAJ11675.1 - 0.11 11.5 2.8 0.16 10.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Peptidase_S8 PF00082.22 OAJ11685.1 - 4e-37 128.1 3.6 6.5e-37 127.4 3.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 OAJ11685.1 - 4.5e-26 90.7 0.2 8.8e-26 89.8 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 OAJ11685.1 - 0.0045 17.7 2.2 0.047 14.5 2.2 2.4 1 1 0 1 1 1 1 Peptidase S8 pro-domain F-box-like PF12937.7 OAJ11686.1 - 8.8e-12 44.7 0.1 8.8e-12 44.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ11686.1 - 1.4e-07 31.2 1.4 3.1e-07 30.1 0.1 2.1 2 0 0 2 2 2 1 F-box domain PQQ PF01011.21 OAJ11686.1 - 0.0037 17.1 0.0 0.77 9.8 0.0 2.6 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 OAJ11686.1 - 0.027 14.1 0.0 0.14 11.7 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain Mpp10 PF04006.12 OAJ11700.1 - 0.00043 18.9 29.4 0.00043 18.9 29.4 2.7 1 1 1 2 2 2 1 Mpp10 protein DENN PF02141.21 OAJ11701.1 - 5.9e-22 78.5 0.0 9.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain IFT20 PF14931.6 OAJ11701.1 - 0.033 14.4 5.9 0.083 13.1 5.9 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 APG6_N PF17675.1 OAJ11701.1 - 0.046 14.3 11.8 0.023 15.2 8.7 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 OAJ11701.1 - 0.2 10.9 9.8 0.53 9.6 9.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 OAJ11701.1 - 0.33 9.8 14.5 0.042 12.7 10.4 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 OAJ11701.1 - 0.35 10.2 14.1 0.11 11.9 10.4 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HMMR_N PF15905.5 OAJ11701.1 - 0.52 9.7 11.3 0.12 11.8 7.5 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SF-assemblin PF06705.11 OAJ11701.1 - 0.77 9.1 10.6 0.093 12.1 5.7 1.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF724 PF05266.14 OAJ11701.1 - 1.8 8.3 15.2 0.29 11.0 10.6 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF724) Filament PF00038.21 OAJ11701.1 - 2.4 7.7 19.6 0.16 11.6 11.7 2.5 2 1 1 3 3 3 0 Intermediate filament protein DUF4201 PF13870.6 OAJ11701.1 - 2.9 7.6 12.4 0.39 10.4 7.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SWIRM-assoc_1 PF16495.5 OAJ11701.1 - 3.4 7.7 13.8 0.28 11.1 8.5 2.0 2 0 0 2 2 2 0 SWIRM-associated region 1 AAA_13 PF13166.6 OAJ11701.1 - 4.6 5.8 9.1 0.96 8.0 4.3 1.8 2 0 0 2 2 2 0 AAA domain Cluap1 PF10234.9 OAJ11701.1 - 5.2 6.4 12.2 0.35 10.2 5.7 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.9 OAJ11701.1 - 5.3 6.0 11.2 3.3 6.7 4.9 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GPO PF05929.11 OAJ11701.1 - 8.7 5.9 10.1 0.74 9.4 4.1 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DDE_3 PF13358.6 OAJ11713.1 - 2.3e-27 95.6 0.0 3.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ11713.1 - 0.00014 22.4 0.0 0.00042 20.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain rve PF00665.26 OAJ11713.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain HTH_7 PF02796.15 OAJ11713.1 - 0.034 14.2 0.9 0.23 11.5 0.0 2.8 4 0 0 4 4 4 0 Helix-turn-helix domain of resolvase HTH_33 PF13592.6 OAJ11713.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn helix DUF4684 PF15736.5 OAJ11713.1 - 0.06 12.0 0.7 0.086 11.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) FAM220 PF15487.6 OAJ11714.1 - 0.18 11.4 10.8 1.9 8.1 0.9 2.2 2 0 0 2 2 2 0 FAM220 family NDC10_II PF16787.5 OAJ11715.1 - 2.7e-23 82.5 0.1 6e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF3235 PF11574.8 OAJ11715.1 - 0.094 13.6 0.2 0.26 12.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Osmo_CC PF08946.10 OAJ11715.1 - 0.14 12.4 0.3 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Histone PF00125.24 OAJ11726.1 - 3e-27 95.6 0.2 4.3e-27 95.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 OAJ11726.1 - 0.076 13.6 1.4 0.13 12.9 1.4 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain UBM PF14377.6 OAJ11727.1 - 0.055 12.9 3.0 0.73 9.4 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin binding region Tup_N PF08581.10 OAJ11728.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 Tup N-terminal ADIP PF11559.8 OAJ11728.1 - 0.18 11.9 3.6 6.8 6.8 0.2 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 OAJ11728.1 - 1.3 8.9 3.9 1.5 8.6 0.1 2.4 2 1 0 2 2 2 0 Septum formation initiator RT_RNaseH_2 PF17919.1 OAJ11743.1 - 1.1e-31 108.8 0.0 2.4e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11743.1 - 8.6e-28 96.7 0.0 2.1e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ11743.1 - 4.5e-19 68.9 0.0 8.7e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ11743.1 - 1.7e-14 54.0 0.1 6.7e-14 52.1 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ11743.1 - 2.2e-09 37.3 0.5 4.7e-09 36.2 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-CCHC PF00098.23 OAJ11743.1 - 0.004 17.2 8.3 0.004 17.2 8.3 2.6 3 0 0 3 3 3 1 Zinc knuckle rve_3 PF13683.6 OAJ11743.1 - 0.037 13.8 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain RT_RNaseH PF17917.1 OAJ11754.1 - 1.5e-37 128.1 0.1 2.7e-37 127.2 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ11754.1 - 1.8e-33 114.5 0.0 6e-33 112.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ11754.1 - 8.5e-31 107.2 0.1 1.4e-30 106.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ11754.1 - 1.3e-20 73.2 0.0 3.7e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ11754.1 - 5.4e-14 52.4 0.0 8.4e-13 48.6 0.0 3.0 4 0 0 4 4 4 1 Integrase core domain Retrotrans_gag PF03732.17 OAJ11754.1 - 6.3e-09 36.0 0.8 3.4e-08 33.6 0.0 2.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 OAJ11754.1 - 1.1e-05 25.2 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Asp_protease_2 PF13650.6 OAJ11754.1 - 0.00072 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ11754.1 - 0.001 19.3 0.0 0.0051 17.0 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger RVP_2 PF08284.11 OAJ11754.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ11754.1 - 0.0059 17.1 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve_3 PF13683.6 OAJ11754.1 - 0.029 14.2 0.0 2.8 7.8 0.0 2.9 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.27 OAJ11766.1 - 1.8e-23 83.2 0.0 3.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 OAJ11766.1 - 1e-14 54.4 0.0 1.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ11766.1 - 1.7e-14 53.7 0.0 5.2e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11766.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ11766.1 - 0.0032 17.7 0.0 0.0076 16.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ11766.1 - 0.0089 16.6 0.5 0.034 14.8 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11766.1 - 0.12 13.0 0.0 0.3 11.7 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVT_1 PF00078.27 OAJ11784.1 - 2.6e-22 79.4 0.0 4.3e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11784.1 - 8.1e-14 51.5 0.0 2.9e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ11784.1 - 0.00022 21.8 0.0 0.00051 20.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 OAJ11784.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 OAJ11784.1 - 0.00088 19.8 0.0 0.0025 18.3 0.0 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ11803.1 - 3.4e-05 24.4 0.0 0.0001 22.8 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ11803.1 - 0.0026 18.3 0.0 0.0065 17.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_H2C2 PF17921.1 OAJ11804.1 - 8.1e-17 61.1 0.1 1.7e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ11804.1 - 4.2e-15 55.9 0.0 7.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ11804.1 - 2.3e-14 53.2 0.0 5.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ11804.1 - 3.8e-07 30.3 0.0 9.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ11804.1 - 0.00062 20.0 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ11804.1 - 0.0071 16.5 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger PH_10 PF15411.6 OAJ11819.1 - 2.2e-21 76.4 0.0 4.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 OAJ11819.1 - 2.5e-06 27.8 0.0 0.047 13.9 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 OAJ11819.1 - 4.2e-05 23.5 0.0 0.001 19.0 0.0 2.7 1 1 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.29 OAJ11819.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain LOR PF04525.12 OAJ11820.1 - 3.2e-27 95.3 0.0 4.1e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 LURP-one-related DUF4580 PF15162.6 OAJ11820.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) MFS_1 PF07690.16 OAJ11843.1 - 3.1e-17 62.5 46.1 3.1e-17 62.5 46.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ11843.1 - 3.4e-05 22.5 21.1 9e-05 21.1 21.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) REF PF05755.12 OAJ11843.1 - 0.072 12.9 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) DUF4811 PF16069.5 OAJ11843.1 - 0.39 10.6 1.8 17 5.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) DHHC PF01529.20 OAJ11845.1 - 6.1e-34 117.0 4.1 1.5e-33 115.8 4.1 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Arc_PepC_II PF06847.11 OAJ11845.1 - 6.5 7.3 6.6 0.48 11.0 1.4 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II rve PF00665.26 OAJ11857.1 - 1.3e-17 64.1 0.1 2.1e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ11857.1 - 1.8e-14 53.6 0.1 5e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ11857.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.6 OAJ11857.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 DDE domain RT_RNaseH_2 PF17919.1 OAJ11858.1 - 3.9e-33 113.5 0.0 6.6e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ11858.1 - 3.9e-28 97.8 0.0 7.4e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ11858.1 - 4e-13 49.4 0.0 7.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CPSF_A PF03178.15 OAJ11869.1 - 5.8e-43 147.4 0.0 9.3e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ11869.1 - 1.1e-21 77.0 0.0 5.7e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CSTF2_hinge PF14327.6 OAJ11870.1 - 2.8e-30 104.6 5.7 2.8e-30 104.6 5.7 2.1 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 OAJ11870.1 - 3.1e-22 78.2 0.1 4.7e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 OAJ11870.1 - 7.2e-17 60.7 2.6 7.2e-17 60.7 2.6 3.1 3 0 0 3 3 3 2 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 OAJ11870.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif bZIP_1 PF00170.21 OAJ11888.1 - 0.002 18.2 19.9 0.0068 16.5 13.1 2.8 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAJ11888.1 - 0.7 10.0 23.9 0.35 11.0 14.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper PWI PF01480.17 OAJ11895.1 - 8e-26 90.2 0.0 1.1e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 PWI domain F-box-like PF12937.7 OAJ11896.1 - 0.0021 17.9 0.8 0.006 16.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like Rep_fac-A_C PF08646.10 OAJ11897.1 - 3.1e-56 189.2 2.1 3.2e-55 185.9 1.0 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 OAJ11897.1 - 1.5e-35 121.0 0.3 4.4e-35 119.5 0.3 1.8 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 OAJ11897.1 - 3e-24 84.9 0.0 6.9e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 OAJ11897.1 - 6.3e-13 48.5 0.4 1.1e-10 41.3 0.0 3.0 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 OAJ11897.1 - 0.00013 22.2 0.2 0.0069 16.7 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 OAJ11897.1 - 0.013 15.3 0.1 0.67 9.6 0.0 2.7 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 KDZ PF18758.1 OAJ11910.1 - 3.6e-46 157.6 0.0 5.9e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ11910.1 - 5e-05 23.4 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ11910.1 - 6.5e-05 23.0 0.0 0.00019 21.6 0.0 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 OAJ11910.1 - 0.094 12.6 0.1 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases CIA30 PF08547.12 OAJ11947.1 - 0.029 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) CIA30 PF08547.12 OAJ11948.1 - 0.0083 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PH_12 PF16457.5 OAJ11948.1 - 0.06 13.9 0.2 0.089 13.3 0.2 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain IMUP PF15761.5 OAJ11948.1 - 0.58 10.9 7.4 0.97 10.2 7.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein Syntaphilin PF15290.6 OAJ11948.1 - 5.3 6.6 5.6 7 6.2 5.6 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Tim44 PF04280.15 OAJ11950.1 - 4.1e-16 59.4 1.6 6.3e-13 49.1 0.0 2.9 3 0 0 3 3 3 2 Tim44-like domain FYDLN_acid PF09538.10 OAJ11950.1 - 0.12 13.1 19.1 0.31 11.8 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 OAJ11950.1 - 1.4 9.2 21.2 0.62 10.4 1.6 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.6 OAJ11950.1 - 2.7 7.9 20.3 1.9 8.4 1.2 3.4 3 0 0 3 3 3 0 Spore coat protein CotO SpoIIIAH PF12685.7 OAJ11950.1 - 5 6.9 26.4 2.1 8.1 3.7 3.3 3 0 0 3 3 3 0 SpoIIIAH-like protein NST1 PF13945.6 OAJ11950.1 - 5.7 7.0 19.7 0.44 10.6 2.8 3.2 3 0 0 3 3 3 0 Salt tolerance down-regulator Sec10 PF07393.11 OAJ11959.1 - 1.9e-82 277.9 0.0 4.3e-78 263.4 0.0 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.7 OAJ11959.1 - 0.0054 16.6 0.4 0.021 14.7 0.4 2.1 1 0 0 1 1 1 1 F-box-like tRNA-synt_1b PF00579.25 OAJ11960.1 - 1.2e-56 192.2 0.0 4.5e-56 190.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 OAJ11960.1 - 0.00052 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 OAJ11960.1 - 0.0016 18.1 0.1 0.0038 16.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ctf8 PF09696.10 OAJ11972.1 - 1.7e-07 31.7 1.2 2.7e-05 24.5 0.0 2.2 1 1 1 2 2 2 2 Ctf8 zf-CCCH PF00642.24 OAJ11973.1 - 2e-17 62.6 14.4 1.6e-10 40.6 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ11973.1 - 5.1e-07 29.5 14.3 3.3e-06 26.9 3.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ11973.1 - 0.00074 19.3 1.2 0.00074 19.3 1.2 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ11973.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 OAJ11973.1 - 2.4 8.9 10.4 9.3 7.0 1.7 2.4 1 1 1 2 2 2 0 Torus domain SDA1 PF05285.12 OAJ11989.1 - 2.3e-79 267.4 47.3 2.3e-79 267.4 47.3 3.4 3 1 0 3 3 3 1 SDA1 NUC130_3NT PF08158.12 OAJ11989.1 - 5.3e-15 55.5 0.4 1e-14 54.6 0.4 1.5 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.29 OAJ11990.1 - 6.2e-33 114.0 0.0 2.2e-32 112.2 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ11990.1 - 4.8e-18 65.5 0.0 1.6e-17 63.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ11990.1 - 1.5e-17 63.5 0.9 3.2e-17 62.5 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ11990.1 - 6e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 OAJ11990.1 - 0.044 14.0 1.3 0.64 10.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain DUF2315 PF10231.9 OAJ12001.1 - 1.7e-15 57.2 0.7 5.9e-10 39.3 0.3 2.3 2 0 0 2 2 2 2 Apoptogenic protein 1 MutS_V PF00488.21 OAJ12002.1 - 1.8e-80 269.4 0.1 3.1e-80 268.7 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ12002.1 - 8.5e-37 127.2 2.5 2.3e-36 125.9 0.3 2.4 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 OAJ12002.1 - 4.5e-19 68.6 0.5 1.6e-18 66.9 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 OAJ12002.1 - 2.2e-15 56.8 0.0 8.2e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ12002.1 - 2.8e-15 56.8 0.1 9.3e-15 55.1 0.1 2.0 1 0 0 1 1 1 1 MutS domain II PQQ_2 PF13360.6 OAJ12003.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain G_glu_transpept PF01019.21 OAJ12012.1 - 3.4e-142 474.8 0.0 2.6e-122 409.2 0.0 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Peroxidase_2 PF01328.17 OAJ12013.1 - 3.3e-53 181.0 0.0 4.6e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 HAD_2 PF13419.6 OAJ12029.1 - 3.4e-15 56.6 0.0 8.7e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ12029.1 - 4.4e-10 40.2 0.0 1.6e-08 35.1 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ12029.1 - 0.0049 17.3 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 OAJ12029.1 - 0.043 13.9 0.0 9.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FH2 PF02181.23 OAJ12030.1 - 6.9e-83 278.8 0.0 8.9e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain ATP19 PF11022.8 OAJ12044.1 - 0.6 10.5 1.8 1 9.8 1.8 1.3 1 0 0 1 1 1 0 ATP synthase subunit K TMEM117 PF15113.6 OAJ12046.1 - 0.061 12.3 0.0 0.062 12.2 0.0 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF3416 PF11896.8 OAJ12047.1 - 0.00084 19.7 0.0 0.00084 19.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3416) Vip3A_N PF12495.8 OAJ12047.1 - 0.018 15.0 0.2 0.02 14.8 0.2 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal MutS_II PF05188.17 OAJ12048.1 - 1.7e-08 34.9 0.1 2e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 MutS domain II MutS_V PF00488.21 OAJ12049.1 - 8.3e-16 58.6 1.6 4.8e-11 43.0 0.2 2.4 2 1 1 3 3 3 2 MutS domain V MutS_V PF00488.21 OAJ12050.1 - 0.0017 18.4 0.1 0.0031 17.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain V Adeno_E4_34 PF04528.13 OAJ12050.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region FixO PF02433.15 OAJ12072.1 - 0.029 13.8 0.5 0.036 13.5 0.5 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF2188 PF09954.9 OAJ12072.1 - 0.89 9.8 5.6 0.32 11.2 2.6 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF155 PF02582.14 OAJ12087.1 - 1.8e-33 116.1 0.3 5.4e-31 108.0 0.0 3.2 2 1 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Maf1 PF09174.10 OAJ12087.1 - 0.083 13.0 3.7 0.23 11.6 3.7 1.7 1 0 0 1 1 1 0 Maf1 regulator Dpy19 PF10034.9 OAJ12087.1 - 0.34 9.0 0.7 0.53 8.4 0.7 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Ndc1_Nup PF09531.10 OAJ12087.1 - 3.9 6.0 17.1 3.9 6.1 14.5 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Bul1_N PF04425.12 OAJ12087.1 - 4.9 5.8 12.7 7.7 5.2 12.7 1.2 1 0 0 1 1 1 0 Bul1 N terminus Presenilin PF01080.17 OAJ12087.1 - 5 5.8 17.9 8.2 5.1 17.9 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 OAJ12087.1 - 6.2 5.7 13.3 10 5.0 13.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 OAJ12087.1 - 7.3 4.7 28.9 10 4.2 28.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 OAJ12087.1 - 8.4 6.3 9.2 18 5.2 9.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Endostatin PF06482.11 OAJ12087.1 - 9.4 5.6 14.4 17 4.7 14.4 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin JmjC PF02373.22 OAJ12088.1 - 1.5e-38 131.7 0.5 2.8e-38 130.8 0.5 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ12088.1 - 4.1e-13 49.1 0.9 8e-13 48.1 0.9 1.5 1 0 0 1 1 1 1 jmjN domain DUF5082 PF16888.5 OAJ12088.1 - 0.15 12.3 2.3 0.28 11.5 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 OAJ12088.1 - 3 7.9 15.8 1.7 8.8 7.1 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HMG_box PF00505.19 OAJ12104.1 - 4.5e-10 39.8 1.2 8.5e-10 38.9 1.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 OAJ12104.1 - 0.00089 18.6 0.2 0.0015 17.8 0.2 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box B277 PF17623.2 OAJ12105.1 - 0.004 16.3 3.3 0.0044 16.1 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function KRTAP PF11759.8 OAJ12105.1 - 0.071 13.7 1.6 0.08 13.5 1.6 1.2 1 0 0 1 1 1 0 Keratin-associated matrix UPF0254 PF06787.11 OAJ12105.1 - 0.4 10.4 5.1 0.45 10.3 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) SKG6 PF08693.10 OAJ12105.1 - 9.5 5.7 15.4 8.6e+02 -0.5 15.4 2.2 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Coatomer_E PF04733.14 OAJ12113.1 - 7.3e-44 150.3 8.2 9.2e-44 150.0 8.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_17 PF13431.6 OAJ12113.1 - 0.035 14.5 0.3 9 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ12113.1 - 0.54 10.8 24.4 1 9.9 4.4 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12113.1 - 1.1 9.5 0.1 1.1 9.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12113.1 - 2.7 9.1 20.2 3.5 8.7 2.1 5.7 3 2 2 6 6 6 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.12 OAJ12114.1 - 1e-24 86.5 2.9 2.4e-24 85.3 2.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF5048 PF16467.5 OAJ12114.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) tRNA-synt_1 PF00133.22 OAJ12115.1 - 1.9e-150 502.0 0.0 2.7e-150 501.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ12115.1 - 3.1e-24 85.6 0.0 5.9e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ12115.1 - 6.5e-16 58.1 7.1 8.1e-10 38.0 0.0 4.4 5 0 0 5 5 5 4 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ12115.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ12115.1 - 0.023 14.0 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 OAJ12115.1 - 0.17 11.8 8.9 0.41 10.5 8.9 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS RecR PF02132.15 OAJ12115.1 - 0.48 10.0 2.2 1.3 8.7 2.2 1.7 1 0 0 1 1 1 0 RecR protein UBM PF14377.6 OAJ12129.1 - 1.2 8.7 3.0 22 4.7 0.5 2.6 2 0 0 2 2 2 0 Ubiquitin binding region JmjC PF02373.22 OAJ12143.1 - 5.4e-41 139.6 0.1 1.2e-40 138.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 OAJ12143.1 - 1.2e-10 41.2 0.1 2.9e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 OAJ12143.1 - 8.9e-10 38.7 1.8 8.9e-10 38.7 1.8 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAJ12143.1 - 6.8e-09 35.9 4.5 1.7e-08 34.6 1.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 OAJ12143.1 - 2.8 7.9 6.3 7.3 6.6 6.3 1.7 1 0 0 1 1 1 0 PHD-finger Spt20 PF12090.8 OAJ12143.1 - 4.5 6.8 23.3 12 5.4 23.3 1.7 1 0 0 1 1 1 0 Spt20 family CENP-C_C PF11699.8 OAJ12155.1 - 1.2e-27 95.9 0.3 2.2e-27 95.1 0.3 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 OAJ12155.1 - 0.00029 20.5 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DTHCT PF08070.11 OAJ12155.1 - 0.02 15.6 1.4 0.02 15.6 1.4 5.8 5 1 1 6 6 6 0 DTHCT (NUC029) region 60KD_IMP PF02096.20 OAJ12156.1 - 5.9e-09 36.0 0.0 0.002 18.1 0.0 2.5 2 1 0 2 2 2 2 60Kd inner membrane protein NDC10_II PF16787.5 OAJ12174.1 - 2.1e-45 155.2 0.0 3.5e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ12174.1 - 0.0012 19.1 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_28 PF13518.6 OAJ12174.1 - 0.065 13.4 0.9 0.75 10.0 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 OAJ12174.1 - 0.2 11.5 3.0 0.41 10.5 0.0 3.1 3 1 1 4 4 4 0 Homeodomain-like domain LTV PF04180.14 OAJ12194.1 - 1.1e-69 236.1 25.8 1.1e-69 236.1 25.8 1.9 1 1 1 2 2 2 1 Low temperature viability protein Peptidase_C8 PF03569.13 OAJ12194.1 - 0.0077 15.8 0.3 0.017 14.7 0.3 1.5 1 0 0 1 1 1 1 Peptidase family C8 Importin_rep_6 PF18829.1 OAJ12194.1 - 0.49 10.6 3.6 1.5 9.0 3.6 1.8 1 0 0 1 1 1 0 Importin repeat 6 CwfJ_C_2 PF04676.14 OAJ12196.1 - 4.8e-26 91.5 0.0 6e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 FMO-like PF00743.19 OAJ12209.1 - 1.9e-33 115.7 0.0 5.9e-19 67.9 0.0 3.1 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 OAJ12209.1 - 3.9e-10 39.5 0.1 8e-05 22.0 0.0 3.9 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ12209.1 - 4.8e-06 25.9 0.1 0.0021 17.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAJ12209.1 - 9.1e-06 25.1 0.0 0.00019 20.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ12209.1 - 2.5e-05 24.3 0.0 0.00051 20.1 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ12209.1 - 0.0014 18.8 0.1 0.003 17.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ12209.1 - 0.0073 15.9 0.2 0.21 11.1 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ12209.1 - 0.017 14.4 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.15 OAJ12209.1 - 0.044 13.1 0.0 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain SWIRM-assoc_2 PF16496.5 OAJ12210.1 - 0.075 11.9 7.2 0.096 11.5 7.2 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal FGF-BP1 PF06473.12 OAJ12210.1 - 0.29 11.0 5.7 0.56 10.0 5.7 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Med19 PF10278.9 OAJ12210.1 - 0.37 10.7 8.9 0.61 10.0 8.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RAP1 PF07218.11 OAJ12210.1 - 4.1 5.6 7.8 4.5 5.4 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FHA PF00498.26 OAJ12211.1 - 2e-14 53.7 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ12211.1 - 0.0036 17.6 0.0 0.12 12.7 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Apt1 PF10351.9 OAJ12211.1 - 0.97 8.2 4.8 1.1 8.0 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RVT_1 PF00078.27 OAJ12224.1 - 2.3e-31 109.1 0.0 3.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ12224.1 - 3.9e-11 42.8 0.0 7.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ12224.1 - 0.00013 21.6 0.6 0.00042 19.9 0.0 2.1 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 OAJ12225.1 - 6.5e-09 36.1 0.1 1.4e-08 35.0 0.1 1.6 1 1 0 1 1 1 1 RNase H adh_short PF00106.25 OAJ12239.1 - 1.4e-26 93.2 0.2 8e-17 61.3 0.2 3.0 2 2 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12239.1 - 5.9e-17 62.0 0.0 1.7e-15 57.3 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ12239.1 - 7.3e-08 32.2 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ12239.1 - 9.1e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ12239.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 OAJ12239.1 - 0.21 11.4 0.7 20 5.0 0.4 2.8 1 1 0 2 2 2 0 KR domain DDHD PF02862.17 OAJ12240.1 - 0.034 14.3 11.5 0.33 11.1 5.6 2.9 3 0 0 3 3 3 0 DDHD domain FliP PF00813.20 OAJ12240.1 - 0.21 11.5 5.1 28 4.5 0.0 2.3 2 0 0 2 2 2 0 FliP family Lant_dehydr_C PF14028.6 OAJ12240.1 - 0.86 9.1 8.4 3.6 7.1 4.7 2.3 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term Spore_III_AF PF09581.10 OAJ12240.1 - 1.4 8.9 8.4 3.7 7.5 8.4 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) SpoIIP PF07454.11 OAJ12240.1 - 1.9 7.9 14.3 0.33 10.4 4.2 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 OAJ12240.1 - 3.1 8.1 14.2 0.63 10.4 5.8 2.7 2 0 0 2 2 2 0 Enhancer of polycomb-like WWE PF02825.20 OAJ12240.1 - 3.4 8.3 9.3 8.7 7.0 9.3 1.6 1 0 0 1 1 1 0 WWE domain RIFIN PF02009.16 OAJ12240.1 - 3.5 7.4 12.2 0.044 13.7 4.1 1.8 2 0 0 2 2 2 0 Rifin CLN3 PF02487.17 OAJ12240.1 - 3.5 6.6 12.1 15 4.5 0.1 2.3 2 0 0 2 2 2 0 CLN3 protein TMEM154 PF15102.6 OAJ12240.1 - 7.5 6.5 0.0 7.5 6.5 0.0 3.9 4 1 0 4 4 4 0 TMEM154 protein family Hira PF07569.11 OAJ12240.1 - 8.6 6.0 8.8 18 4.9 8.8 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Neur_chan_memb PF02932.16 OAJ12240.1 - 9.7 6.2 9.4 40 4.1 5.7 2.6 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region RRM_1 PF00076.22 OAJ12254.1 - 4.7e-10 39.1 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ12254.1 - 0.059 13.0 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGI PF00342.19 OAJ12255.1 - 4.5e-225 747.8 0.1 5.2e-225 747.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Inhibitor_Mig-6 PF11555.8 OAJ12255.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DUF5052 PF16475.5 OAJ12255.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5052) SNF5 PF04855.12 OAJ12256.1 - 2e-56 191.5 2.8 1.8e-53 181.8 2.8 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 FbpC_C_terminal PF17845.1 OAJ12256.1 - 0.0066 16.5 0.3 0.016 15.3 0.3 1.5 1 0 0 1 1 1 1 FbpC C-terminal regulatory nucleotide binding domain DUF3432 PF11914.8 OAJ12256.1 - 6.5 7.1 12.4 12 6.2 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) MBF1 PF08523.10 OAJ12257.1 - 1.6e-19 70.1 0.8 3.3e-19 69.1 0.8 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 OAJ12257.1 - 2.1e-11 43.7 0.3 3.7e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 OAJ12257.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 OAJ12257.1 - 0.0055 16.7 0.2 0.0086 16.1 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HpcH_HpaI PF03328.14 OAJ12257.1 - 0.043 13.0 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Cation_efflux PF01545.21 OAJ12289.1 - 4.7e-26 91.8 9.7 6.2e-26 91.4 9.7 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ12289.1 - 6.1e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1772 PF08592.11 OAJ12291.1 - 2.6e-16 60.2 1.5 2.9e-16 60.0 1.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Muskelin_N PF06588.11 OAJ12311.1 - 5.9e-23 81.8 0.0 9.9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Pox_Ag35 PF03286.14 OAJ12311.1 - 3.5 7.4 9.5 0.27 11.0 4.3 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SOG2 PF10428.9 OAJ12311.1 - 4.8 6.3 15.3 7.3 5.7 15.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.11 OAJ12311.1 - 6.8 4.8 8.7 10 4.3 8.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF520 PF04461.13 OAJ12312.1 - 0.06 13.5 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF520) DUF4404 PF14357.6 OAJ12312.1 - 1.7 9.4 4.4 2.6 8.7 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) RVT_2 PF07727.14 OAJ12328.1 - 1.5e-66 224.5 0.0 1.9e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 OAJ12328.1 - 0.022 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PAT1 PF09770.9 OAJ12328.1 - 0.33 9.2 3.3 0.48 8.6 3.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HTH_32 PF13565.6 OAJ12328.1 - 3.3 8.4 8.4 0.57 10.8 2.1 2.7 2 0 0 2 2 2 0 Homeodomain-like domain Peptidase_M24 PF00557.24 OAJ12329.1 - 2.2e-38 132.0 0.0 3e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 OAJ12329.1 - 0.024 14.8 5.0 0.039 14.1 5.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAJ12329.1 - 0.41 8.9 5.4 0.56 8.4 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein LAT PF15234.6 OAJ12329.1 - 0.8 9.4 2.8 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells PGA2 PF07543.12 OAJ12329.1 - 4.7 7.2 12.8 0.26 11.3 6.0 2.2 3 0 0 3 3 3 0 Protein trafficking PGA2 NOA36 PF06524.12 OAJ12329.1 - 7.3 5.8 7.3 15 4.8 7.3 1.5 1 0 0 1 1 1 0 NOA36 protein Retrotran_gag_2 PF14223.6 OAJ12330.1 - 3.2e-07 30.1 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ12330.1 - 1.1e-05 25.3 2.7 2.3e-05 24.2 2.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Fungus-induced PF10917.8 OAJ12330.1 - 1.8 8.9 5.1 3.8 7.9 5.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein YlbD_coat PF14071.6 OAJ12355.1 - 0.0086 16.3 0.8 0.014 15.7 0.8 1.4 1 0 0 1 1 1 1 Putative coat protein GIT1_C PF12205.8 OAJ12355.1 - 0.05 13.7 0.3 0.093 12.8 0.3 1.5 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF4972 PF16342.5 OAJ12355.1 - 0.44 10.2 2.1 1.6 8.4 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) RT_RNaseH_2 PF17919.1 OAJ12356.1 - 1.2e-15 57.3 0.0 1.2e-14 54.2 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ12356.1 - 1.3e-15 57.6 0.0 9e-15 54.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ12356.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 OAJ12356.1 - 6.5e-06 26.6 0.0 2.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ12356.1 - 1.2e-05 25.8 0.0 3.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 OAJ12356.1 - 1.5e-05 24.8 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 OAJ12356.1 - 0.0032 17.2 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 OAJ12356.1 - 0.0042 16.9 0.4 0.034 14.0 0.2 2.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 OAJ12356.1 - 0.11 12.8 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease SBF PF01758.16 OAJ12369.1 - 1.8e-43 148.5 14.4 1.8e-43 148.5 14.4 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family MFS_1 PF07690.16 OAJ12370.1 - 1.6e-41 142.4 50.2 1.6e-41 142.4 50.2 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ12370.1 - 1.2e-08 34.3 16.3 1.2e-08 34.3 16.3 3.2 2 2 0 3 3 3 2 Sugar (and other) transporter DUF3930 PF13067.6 OAJ12370.1 - 0.069 13.4 0.4 0.2 11.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) SirB PF04247.12 OAJ12370.1 - 1.2 9.3 10.2 0.33 11.0 0.3 3.9 4 0 0 4 4 4 0 Invasion gene expression up-regulator, SirB SUIM_assoc PF16619.5 OAJ12371.1 - 0.072 13.2 0.2 0.072 13.2 0.2 3.4 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Helitron_like_N PF14214.6 OAJ12390.1 - 8.3e-11 42.5 0.3 2e-10 41.2 0.3 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Toxin_29 PF08116.11 OAJ12390.1 - 0.48 10.5 2.7 0.99 9.5 2.7 1.4 1 0 0 1 1 1 0 PhTx neurotoxin family ACC_epsilon PF13822.6 OAJ12410.1 - 0.7 10.6 4.1 3.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit UPF0203 PF05254.12 OAJ12425.1 - 2.8e-16 59.5 0.0 2.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Ndc1_Nup PF09531.10 OAJ12425.1 - 0.05 12.3 1.0 0.055 12.2 1.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UCR_hinge PF02320.16 OAJ12425.1 - 0.1 12.8 0.5 11 6.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein EPL1 PF10513.9 OAJ12426.1 - 0.1 13.0 2.9 0.14 12.5 2.9 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like NST1 PF13945.6 OAJ12426.1 - 1.7 8.7 13.7 2.3 8.3 13.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator AdoMet_MTase PF07757.13 OAJ12427.1 - 1.4e-30 105.9 0.0 1.6e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 OAJ12427.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-Tim10_DDP PF02953.15 OAJ12428.1 - 1.3e-18 66.4 0.4 1.8e-18 65.9 0.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PCI PF01399.27 OAJ12429.1 - 5.4e-15 55.8 0.0 2.5e-14 53.6 0.0 2.1 2 1 0 2 2 2 1 PCI domain SRC-1 PF08832.10 OAJ12429.1 - 5.9 8.0 5.6 2.3 9.3 0.4 2.8 3 0 0 3 3 3 0 Steroid receptor coactivator Collagen PF01391.18 OAJ12442.1 - 1.2e-17 63.4 71.8 7e-10 38.5 32.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Methyltransf_23 PF13489.6 OAJ12458.1 - 0.074 12.9 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ12458.1 - 0.15 12.8 0.2 1.2 9.9 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 OAJ12458.1 - 0.26 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Thymidylat_synt PF00303.19 OAJ12459.1 - 2e-100 335.4 0.0 2.9e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase His_Phos_1 PF00300.22 OAJ12459.1 - 1.2e-36 126.2 0.7 1.8e-35 122.4 0.7 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_holin_2_3 PF16080.5 OAJ12460.1 - 0.066 13.0 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 WD40 PF00400.32 OAJ12473.1 - 3.5e-51 170.1 24.8 3.1e-09 37.3 0.6 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ12473.1 - 1.1e-17 64.1 0.4 5e-05 23.5 0.0 5.4 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ12473.1 - 3.3e-08 32.7 3.8 0.77 8.3 0.0 5.9 3 1 2 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 OAJ12473.1 - 3.7e-08 33.5 0.0 0.00085 19.2 0.0 3.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 OAJ12473.1 - 9.9e-07 28.0 2.9 0.0086 15.0 0.0 4.6 2 1 3 5 5 5 2 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 OAJ12473.1 - 1.4e-05 24.2 0.2 0.66 8.9 0.0 4.7 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ12473.1 - 0.00037 19.9 0.1 0.0038 16.6 0.0 2.5 2 1 1 3 3 3 1 WD40-like domain Frtz PF11768.8 OAJ12473.1 - 0.0087 14.4 0.1 0.023 13.0 0.0 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz SR-25 PF10500.9 OAJ12473.1 - 0.78 9.3 5.7 1.8 8.1 5.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ras PF00071.22 OAJ12474.1 - 2.7e-33 114.8 0.5 6.3e-16 58.4 0.1 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 OAJ12474.1 - 4.3e-12 46.3 0.1 5.7e-11 42.7 0.0 2.1 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 OAJ12474.1 - 0.00081 19.3 0.3 0.31 10.9 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase Arf PF00025.21 OAJ12474.1 - 0.012 15.0 0.0 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ12474.1 - 0.025 14.6 0.1 0.031 14.4 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ12474.1 - 0.033 13.7 0.0 7.5 6.1 0.0 2.2 1 1 0 2 2 2 0 Ferrous iron transport protein B TniB PF05621.11 OAJ12474.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 OAJ12474.1 - 0.066 13.5 0.0 0.098 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain TMEM237 PF15383.6 OAJ12475.1 - 0.00032 19.9 0.0 0.00087 18.5 0.0 1.7 2 0 0 2 2 2 1 Transmembrane protein 237 Sugarporin_N PF11471.8 OAJ12475.1 - 0.042 13.8 2.5 0.12 12.3 2.5 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF4279 PF14106.6 OAJ12475.1 - 0.25 11.5 1.0 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) ArsR PF09824.9 OAJ12476.1 - 0.01 15.4 0.3 0.016 14.8 0.3 1.3 1 0 0 1 1 1 0 ArsR transcriptional regulator SPESP1 PF15754.5 OAJ12476.1 - 0.11 11.6 8.1 0.14 11.3 8.1 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Het-C PF07217.11 OAJ12476.1 - 0.12 10.9 5.4 0.15 10.6 5.4 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C WD40_alt PF14077.6 OAJ12476.1 - 0.19 11.6 0.4 0.19 11.6 0.4 2.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF2207 PF09972.9 OAJ12476.1 - 0.23 10.2 2.0 0.3 9.8 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Atg14 PF10186.9 OAJ12476.1 - 0.59 9.2 8.3 0.83 8.7 8.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 OAJ12476.1 - 3 7.9 5.9 2.5 8.1 3.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rota_VP2 PF05087.12 OAJ12476.1 - 5.2 5.1 8.9 6.1 4.8 8.9 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein zf-BED PF02892.15 OAJ12489.1 - 0.0062 16.5 0.8 0.011 15.7 0.8 1.4 1 0 0 1 1 1 1 BED zinc finger RCDG1 PF15725.5 OAJ12490.1 - 5.6 7.5 12.1 0.6 10.6 6.3 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein BUD22 PF09073.10 OAJ12491.1 - 0.26 10.6 14.2 0.35 10.1 14.2 1.1 1 0 0 1 1 1 0 BUD22 zf-CCHC PF00098.23 OAJ12502.1 - 0.027 14.5 7.4 0.054 13.6 7.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ12502.1 - 0.093 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MULE PF10551.9 OAJ12504.1 - 3.2e-20 72.3 0.9 8.8e-20 70.9 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAJ12504.1 - 2.7e-07 30.5 1.4 3.6e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 MuDR family transposase Transposase_mut PF00872.18 OAJ12504.1 - 7e-06 25.1 0.0 1.4e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 Transposase, Mutator family WH1 PF00568.23 OAJ12504.1 - 0.1 12.5 0.2 0.28 11.1 0.2 1.7 2 0 0 2 2 2 0 WH1 domain Ribosomal_S7e PF01251.18 OAJ12504.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e WW PF00397.26 OAJ12516.1 - 0.0036 17.3 0.3 0.0075 16.3 0.3 1.5 1 0 0 1 1 1 1 WW domain Glyco_transf_22 PF03901.17 OAJ12518.1 - 2.7e-70 237.7 14.6 2e-68 231.5 14.3 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family nlz1 PF12402.8 OAJ12518.1 - 0.094 13.2 0.9 20 5.7 0.2 3.1 3 0 0 3 3 3 0 NocA-like zinc-finger protein 1 Prenyltrans PF00432.21 OAJ12532.1 - 1e-21 76.3 11.2 1.9e-07 30.7 0.0 3.8 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Helicase_C_4 PF13871.6 OAJ12532.1 - 0.052 13.2 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue PIP5K PF01504.18 OAJ12533.1 - 1.2e-98 329.7 0.0 3.6e-96 321.6 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase HemX PF04375.14 OAJ12533.1 - 0.66 9.2 11.9 5 6.3 7.4 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Presenilin PF01080.17 OAJ12533.1 - 6.5 5.4 9.2 2.1 7.0 3.0 2.2 2 0 0 2 2 2 0 Presenilin Arm PF00514.23 OAJ12534.1 - 7.4e-75 244.9 30.1 8.5e-13 47.9 0.1 12.3 11 1 2 13 13 13 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ12534.1 - 7.5e-19 67.8 11.7 9.1e-05 22.9 0.2 7.5 5 2 2 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 OAJ12534.1 - 1.6e-18 66.9 7.5 0.0058 17.0 0.0 7.1 3 2 4 7 7 7 5 HEAT repeats HEAT PF02985.22 OAJ12534.1 - 8.9e-15 53.5 12.9 0.87 10.0 0.0 9.1 8 0 0 8 8 8 5 HEAT repeat Adaptin_N PF01602.20 OAJ12534.1 - 2.7e-10 39.4 12.4 1.4e-08 33.8 0.9 2.4 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 OAJ12534.1 - 3.1e-10 38.9 1.8 4.7e-10 38.3 1.8 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 OAJ12534.1 - 1.3e-09 37.8 8.7 0.0008 18.8 1.3 4.5 1 1 2 4 4 4 4 V-ATPase subunit H Arm_2 PF04826.13 OAJ12534.1 - 2e-09 37.3 10.4 5.7e-06 26.0 4.1 2.8 1 1 1 2 2 2 2 Armadillo-like Cnd1 PF12717.7 OAJ12534.1 - 2.1e-06 27.9 8.0 0.056 13.5 0.7 4.5 2 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 OAJ12534.1 - 3e-06 27.3 13.4 0.0017 18.3 0.2 4.4 2 1 2 5 5 5 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 OAJ12534.1 - 5.6e-05 22.7 8.8 0.47 9.8 1.8 4.2 2 1 2 4 4 4 2 Family of unknown function (DUF5578) V-ATPase_H_C PF11698.8 OAJ12534.1 - 6.6e-05 23.0 5.5 4.5 7.4 0.0 5.1 2 1 3 5 5 5 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 OAJ12534.1 - 0.023 15.3 0.1 3.4 8.3 0.0 3.2 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 OAJ12534.1 - 0.024 14.6 5.4 3.2 7.7 0.4 3.7 3 1 0 4 4 4 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.16 OAJ12534.1 - 0.025 15.2 9.8 1.1e+02 3.9 0.0 7.4 9 0 0 9 9 7 0 PBS lyase HEAT-like repeat IFRD PF05004.13 OAJ12534.1 - 0.031 13.4 8.5 0.93 8.5 0.1 4.2 3 2 1 4 4 4 0 Interferon-related developmental regulator (IFRD) YqfD PF06898.11 OAJ12534.1 - 0.032 13.1 0.0 0.075 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD CTNNBL PF08216.11 OAJ12534.1 - 0.14 12.3 7.2 46 4.2 0.2 5.0 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 OAJ12534.1 - 0.19 11.7 3.4 2.4 8.2 0.0 3.6 2 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain CDP-OH_P_transf PF01066.21 OAJ12556.1 - 9.9e-16 58.3 0.2 9.9e-16 58.3 0.2 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 OAJ12557.1 - 4.6e-46 157.3 0.0 7.1e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12557.1 - 3.7e-43 147.7 0.0 5.1e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 OAJ12557.1 - 0.00056 19.7 5.8 0.0011 18.8 5.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Haspin_kinase PF12330.8 OAJ12557.1 - 0.01 14.8 0.0 0.01 14.8 0.0 1.6 2 0 0 2 2 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ12557.1 - 0.011 14.5 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 OAJ12557.1 - 0.014 15.3 1.2 0.016 15.1 0.0 1.6 2 0 0 2 2 1 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ12557.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-HC5HC2H PF13771.6 OAJ12557.1 - 0.1 12.9 2.4 0.23 11.7 2.4 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAJ12557.1 - 0.16 12.1 3.9 0.32 11.2 3.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF2956 PF11169.8 OAJ12557.1 - 0.24 11.6 3.5 0.62 10.3 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) TFIIF_alpha PF05793.12 OAJ12557.1 - 0.72 8.4 20.1 0.022 13.4 12.5 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rrn6 PF10214.9 OAJ12557.1 - 0.82 8.1 18.8 1.3 7.5 18.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MAP65_ASE1 PF03999.12 OAJ12557.1 - 1.8 7.2 12.1 2.9 6.5 12.1 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Paf1 PF03985.13 OAJ12557.1 - 1.9 7.4 12.0 3.5 6.5 12.0 1.4 1 0 0 1 1 1 0 Paf1 PHD PF00628.29 OAJ12557.1 - 2.1 8.3 6.8 4.4 7.3 6.8 1.5 1 0 0 1 1 1 0 PHD-finger PI3K_1B_p101 PF10486.9 OAJ12557.1 - 3.8 5.2 10.9 5.8 4.6 10.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Phage_integrase PF00589.22 OAJ12570.1 - 7.6e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Phage integrase family Asp_protease_2 PF13650.6 OAJ12580.1 - 1.8e-05 25.3 0.0 3.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ12580.1 - 0.003 18.1 0.0 0.009 16.5 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ12580.1 - 0.033 14.5 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease dUTPase PF00692.19 OAJ12580.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 1 0 1 1 1 0 dUTPase Retrotrans_gag PF03732.17 OAJ12581.1 - 0.004 17.4 1.1 0.0084 16.4 0.6 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Ras PF00071.22 OAJ12611.1 - 4.7e-33 114.1 0.0 5.3e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ12611.1 - 1.9e-28 99.1 0.0 2.2e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ12611.1 - 2.4e-08 33.6 0.0 2.7e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ12611.1 - 0.00022 21.3 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ12611.1 - 0.002 17.5 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 OAJ12611.1 - 0.028 14.8 0.0 0.031 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ12611.1 - 0.049 13.5 0.1 0.091 12.7 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 OAJ12611.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAJ12611.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein RRM_1 PF00076.22 OAJ12612.1 - 1.3e-16 60.2 0.0 6.2e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ12612.1 - 0.2 11.3 0.0 1.3 8.6 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.21 OAJ12613.1 - 2.3e-72 243.7 0.0 2.6e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CbiG_mid PF11761.8 OAJ12626.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.4 1 1 0 1 1 1 0 Cobalamin biosynthesis central region NDC10_II PF16787.5 OAJ12639.1 - 8.7e-53 179.4 0.0 1.3e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ12639.1 - 2.4e-13 50.2 0.0 5.5e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Sporozoite_P67 PF05642.11 OAJ12639.1 - 0.12 10.4 3.5 0.21 9.6 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP_synt_H PF05493.13 OAJ12640.1 - 1.1e-20 73.8 4.4 1.3e-20 73.6 4.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.7 OAJ12640.1 - 5.9 6.9 7.4 2.2e+02 1.9 7.4 2.2 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1720 PF08226.11 OAJ12654.1 - 0.63 10.5 15.8 7.9 7.0 15.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Complex1_LYR_2 PF13233.6 OAJ12655.1 - 1.8e-07 31.8 0.2 5.9e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ12655.1 - 1.1e-05 25.4 0.5 1.1e-05 25.4 0.5 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Dor1 PF04124.12 OAJ12670.1 - 0.1 11.3 5.8 0.37 9.4 0.9 2.6 3 0 0 3 3 3 0 Dor1-like family Herpes_capsid PF06112.11 OAJ12670.1 - 0.21 11.7 0.1 0.21 11.7 0.1 2.3 1 1 1 2 2 2 0 Gammaherpesvirus capsid protein G-patch PF01585.23 OAJ12671.1 - 9e-06 25.5 0.2 1.8e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 OAJ12671.1 - 0.0098 16.2 4.0 0.017 15.4 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.8 OAJ12671.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Ribosomal_60s PF00428.19 OAJ12671.1 - 1.2 9.8 0.0 1.2 9.8 0.0 4.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein MID_MedPIWI PF18296.1 OAJ12672.1 - 0.0011 18.9 0.9 0.0015 18.4 0.9 1.3 1 0 0 1 1 1 1 MID domain of medPIWI FUSC PF04632.12 OAJ12672.1 - 2.8 6.4 10.7 0.15 10.5 2.9 2.2 2 1 0 2 2 2 0 Fusaric acid resistance protein family Myc_N PF01056.18 OAJ12673.1 - 0.016 15.1 1.4 0.025 14.5 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_B PF00136.21 OAJ12689.1 - 1.8e-151 504.9 1.5 3e-151 504.2 1.5 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ12689.1 - 6.8e-74 249.0 0.0 9.4e-66 222.2 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ12689.1 - 4.7e-17 62.2 7.2 1.1e-16 61.1 7.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 OAJ12689.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 OAJ12689.1 - 0.0019 17.1 0.6 0.0062 15.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 OAJ12689.1 - 0.043 13.8 0.1 0.21 11.6 0.1 2.3 1 1 0 1 1 1 0 RNase_H superfamily Amino_oxidase PF01593.24 OAJ12690.1 - 6.7e-61 207.0 0.2 7.6e-61 206.8 0.2 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ12690.1 - 2.9e-11 43.4 0.5 6.9e-11 42.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ12690.1 - 1.7e-06 27.0 2.5 0.0037 16.0 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAJ12690.1 - 3.7e-06 26.8 3.1 1.2e-05 25.1 3.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ12690.1 - 2.6e-05 23.5 1.1 4.1e-05 22.9 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ12690.1 - 0.00029 20.2 1.0 0.052 12.8 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ12690.1 - 0.00035 19.9 0.2 0.00055 19.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAJ12690.1 - 0.00054 20.5 0.7 0.0099 16.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ12690.1 - 0.0012 18.1 1.7 0.018 14.3 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ12690.1 - 0.0037 16.5 0.3 0.007 15.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 OAJ12690.1 - 0.013 15.5 2.2 0.66 10.0 0.2 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAJ12690.1 - 0.021 13.9 0.2 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 OAJ12690.1 - 0.025 14.0 0.6 0.036 13.4 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAJ12690.1 - 0.043 13.1 0.5 0.068 12.5 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.20 OAJ12706.1 - 1.8e-09 37.3 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 OAJ12706.1 - 2.3e-09 37.2 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ12706.1 - 8.9e-09 35.9 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ12706.1 - 3.1e-06 27.1 0.0 4.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 OAJ12706.1 - 2.2e-05 25.0 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ12706.1 - 0.00016 21.5 0.1 0.00026 20.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAJ12706.1 - 0.00017 21.0 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 OAJ12706.1 - 0.00024 21.8 0.2 0.0068 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 OAJ12706.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 OAJ12706.1 - 0.00081 19.4 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 OAJ12706.1 - 0.0018 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 OAJ12706.1 - 0.0053 16.2 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 OAJ12706.1 - 0.074 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 OAJ12706.1 - 0.081 13.0 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.18 OAJ12706.1 - 0.086 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 OAJ12706.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Phage_integrase PF00589.22 OAJ12707.1 - 0.00025 20.9 0.0 0.00079 19.2 0.0 1.8 1 0 0 1 1 1 1 Phage integrase family AF-4 PF05110.13 OAJ12707.1 - 0.023 12.8 40.8 0.016 13.3 20.2 2.6 2 0 0 2 2 2 0 AF-4 proto-oncoprotein SPX PF03105.19 OAJ12707.1 - 0.12 12.3 32.9 0.0072 16.3 3.4 2.9 3 0 0 3 3 3 0 SPX domain Apt1 PF10351.9 OAJ12707.1 - 3.3 6.5 27.1 0.69 8.7 14.6 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain RVT_1 PF00078.27 OAJ12730.1 - 9.9e-18 64.5 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCDHK_Adom3 PF10436.9 OAJ12731.1 - 1.4e-39 135.5 0.0 2.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ12731.1 - 2.2e-09 37.8 0.0 1.2e-05 25.8 0.0 3.1 2 1 1 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ12731.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase V-SNARE_C PF12352.8 OAJ12732.1 - 6e-17 61.7 3.9 1.5e-16 60.4 3.9 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 OAJ12732.1 - 0.00079 19.3 0.0 0.0025 17.7 0.0 1.9 1 0 0 1 1 1 1 Sec20 Caudo_TAP PF02413.17 OAJ12732.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Glyco_hydro_16 PF00722.21 OAJ12744.1 - 5.1e-13 48.9 1.3 7.7e-13 48.3 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.6 OAJ12745.1 - 3.7e-14 53.2 0.4 8.8e-10 38.9 0.3 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 OAJ12745.1 - 6.1e-11 41.6 8.7 5.4e-09 35.2 8.2 3.2 2 1 0 2 2 2 1 Chitin synthase Glyco_transf_21 PF13506.6 OAJ12745.1 - 1.6e-10 40.7 0.0 3.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 OAJ12745.1 - 2.4e-10 40.7 6.1 2.4e-10 40.7 6.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 OAJ12745.1 - 0.0019 18.0 0.0 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 THUMP PF02926.17 OAJ12759.1 - 1.1e-13 51.5 0.1 3e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 THUMP domain Pkinase PF00069.25 OAJ12760.1 - 7.4e-65 218.9 0.0 9.4e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ12760.1 - 3e-44 151.2 0.0 4e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ12760.1 - 3e-07 30.1 0.0 5.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 OAJ12760.1 - 9.7e-06 24.6 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ12760.1 - 5.3e-05 23.3 0.2 0.12 12.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ12760.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ12760.1 - 0.047 12.6 0.0 5.2 5.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain MTP18 PF10558.9 OAJ12776.1 - 2.6e-30 105.6 0.4 3e-30 105.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) TPR_1 PF00515.28 OAJ12778.1 - 4.4e-08 32.6 1.6 0.26 11.2 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ12778.1 - 8e-08 32.5 20.6 0.052 13.8 1.3 6.0 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ12778.1 - 6.7e-07 28.9 9.7 0.051 13.7 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ12778.1 - 0.0022 18.1 5.8 4.2 7.8 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ12778.1 - 0.0029 18.3 14.9 1.6 9.8 0.3 8.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ12778.1 - 0.06 13.4 5.5 42 4.5 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_term_smal PF05944.12 OAJ12778.1 - 0.12 12.3 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 Phage small terminase subunit HbrB PF08539.11 OAJ12778.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 HbrB-like ANAPC3 PF12895.7 OAJ12778.1 - 0.3 11.3 4.9 14 6.0 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAJ12778.1 - 0.33 11.5 11.4 11 6.6 0.2 6.0 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ12778.1 - 0.53 11.0 17.1 2.4 8.9 4.4 5.3 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ12778.1 - 4.9 7.2 14.4 14 5.7 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat Molybdopterin PF00384.22 OAJ12795.1 - 9.8e-72 242.3 0.0 2.1e-36 125.9 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 OAJ12795.1 - 2.6e-14 53.6 0.1 6e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal TPP_enzyme_M PF00205.22 OAJ12795.1 - 0.0041 16.9 0.1 0.44 10.3 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FDF PF09532.10 OAJ12796.1 - 6.9e-08 33.3 0.0 6.9e-08 33.3 0.0 3.3 5 0 0 5 5 5 1 FDF domain LSM14 PF12701.7 OAJ12796.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Scd6-like Sm domain tRNA-synt_1c PF00749.21 OAJ12810.1 - 5.1e-69 232.6 0.0 9.1e-69 231.7 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ESSS PF10183.9 OAJ12811.1 - 2.8e-08 33.9 0.1 3.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PHY PF00360.20 OAJ12829.1 - 7e-26 90.7 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 OAJ12829.1 - 6.1e-17 62.1 0.1 2e-16 60.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ12829.1 - 3.4e-14 52.9 0.0 1.9e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 OAJ12829.1 - 3.3e-11 43.0 1.1 7.7e-11 41.9 1.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 OAJ12829.1 - 3.4e-11 43.9 0.0 1.3e-10 42.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 OAJ12829.1 - 2.7e-10 40.8 0.0 6.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 OAJ12829.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 OAJ12829.1 - 2 8.3 24.2 0.45 10.5 20.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RT_RNaseH PF17917.1 OAJ12845.1 - 1.9e-35 121.3 0.1 3.7e-35 120.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ12845.1 - 2.4e-28 98.1 0.0 5e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ12845.1 - 2.4e-20 73.0 0.0 4.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ12845.1 - 6e-19 68.4 0.0 1.5e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ12845.1 - 2e-17 63.0 0.3 4.6e-17 61.9 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ12845.1 - 7.1e-08 32.2 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 OAJ12845.1 - 3.6e-07 30.0 0.1 3.5e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAJ12845.1 - 0.00052 20.6 0.0 0.002 18.7 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease rve_3 PF13683.6 OAJ12845.1 - 0.02 14.7 0.5 0.066 13.0 0.5 2.0 1 1 0 1 1 1 0 Integrase core domain Retrotrans_gag PF03732.17 OAJ12846.1 - 8.3e-11 42.0 0.6 8.4e-10 38.8 0.6 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ12846.1 - 0.0002 21.3 0.6 0.00033 20.6 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAJ12846.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF4473 PF14747.6 OAJ12846.1 - 0.028 15.0 0.0 0.083 13.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) zf-C2H2_10 PF16588.5 OAJ12846.1 - 0.42 10.4 0.1 0.42 10.4 0.1 1.8 2 0 0 2 2 2 0 C2H2 zinc-finger SPC12 PF06645.13 OAJ12862.1 - 3.7e-26 91.0 0.2 4.4e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2892 PF11127.8 OAJ12862.1 - 0.0019 18.2 1.1 0.0027 17.7 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2892) SDA1 PF05285.12 OAJ12863.1 - 1.4e-05 24.7 16.7 2.7e-05 23.8 16.7 1.5 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 OAJ12863.1 - 2.2 7.6 24.5 4.6 6.6 24.5 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 OAJ12863.1 - 3.9 5.6 28.5 7.3 4.7 28.5 1.4 1 0 0 1 1 1 0 Nop14-like family rve PF00665.26 OAJ12880.1 - 1e-14 54.7 0.2 3.5e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ12880.1 - 8.6e-10 38.6 0.5 1.5e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ12880.1 - 0.04 13.7 0.0 0.14 11.9 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain CDC45 PF02724.14 OAJ12880.1 - 0.082 11.2 1.3 0.12 10.7 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ12880.1 - 0.67 8.1 9.1 0.98 7.6 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family RVT_1 PF00078.27 OAJ12881.1 - 2.4e-20 73.0 0.0 4.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ12881.1 - 0.57 10.4 6.0 0.21 11.8 2.8 1.9 2 0 0 2 2 2 0 Zinc knuckle AA_permease_2 PF13520.6 OAJ12901.1 - 3.4e-42 144.8 21.5 4.2e-42 144.5 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ12902.1 - 1.5e-76 258.0 33.9 1.9e-76 257.6 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease NUP50 PF08911.11 OAJ12937.1 - 3e-06 27.8 0.1 3e-06 27.8 0.1 5.8 5 3 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) DUF4632 PF15451.6 OAJ12937.1 - 0.02 14.9 0.1 0.02 14.9 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4632) Cwf_Cwc_15 PF04889.12 OAJ12937.1 - 0.26 11.0 8.1 0.57 9.9 8.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ12937.1 - 2.9 7.1 10.5 6.1 6.1 10.5 1.5 1 0 0 1 1 1 0 NOA36 protein Sugar_tr PF00083.24 OAJ12938.1 - 3.3e-66 224.0 11.1 3.9e-66 223.8 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ12938.1 - 3.6e-12 45.9 21.0 3.6e-12 45.9 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MMgT PF10270.9 OAJ12940.1 - 3.1e-14 53.1 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter adh_short PF00106.25 OAJ12953.1 - 2.2e-21 76.2 0.0 3.1e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ12953.1 - 1e-17 64.5 0.2 1.3e-17 64.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ12953.1 - 8.5e-11 42.1 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ12953.1 - 2.8e-07 30.2 0.5 4.3e-06 26.4 0.5 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ12953.1 - 0.00014 21.4 0.1 0.049 13.0 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 OAJ12953.1 - 0.00015 21.8 0.1 0.00084 19.5 0.2 2.0 1 1 1 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 OAJ12953.1 - 0.001 18.3 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 OAJ12953.1 - 0.011 15.6 1.5 0.076 12.9 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ12953.1 - 0.085 13.4 1.1 0.37 11.4 0.7 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 OAJ12953.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PI3_PI4_kinase PF00454.27 OAJ12954.1 - 6.6e-33 114.6 0.0 1.2e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 OAJ12954.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Cupin_8 PF13621.6 OAJ12955.1 - 4.1e-37 128.3 0.0 5.6e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain RVT_1 PF00078.27 OAJ12977.1 - 2.1e-35 122.2 0.0 3.7e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UCH PF00443.29 OAJ12994.1 - 1.2e-35 123.3 0.0 2.1e-34 119.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ12994.1 - 1.7e-06 27.9 0.0 0.002 17.8 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase OapA_N PF08525.11 OAJ12994.1 - 0.66 10.0 4.9 1.8 8.6 4.9 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif Ras PF00071.22 OAJ12996.1 - 8.7e-52 175.0 0.3 1e-51 174.8 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ12996.1 - 5.2e-31 107.4 0.1 6.9e-31 107.0 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ12996.1 - 4.2e-16 58.9 0.0 6e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ12996.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ12996.1 - 0.00028 20.3 0.0 0.00034 20.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 OAJ12996.1 - 0.0014 18.1 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 OAJ12996.1 - 0.0026 17.3 0.3 0.012 15.2 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 OAJ12996.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Muskelin_N PF06588.11 OAJ13011.1 - 1.3e-41 142.7 0.3 7.8e-33 114.1 0.0 2.1 2 0 0 2 2 2 2 Muskelin N-terminus Kelch_5 PF13854.6 OAJ13011.1 - 5.5e-12 45.4 1.7 0.00053 19.9 0.0 6.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 OAJ13011.1 - 3e-10 40.0 5.0 0.043 14.1 0.1 6.7 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 OAJ13011.1 - 5.9e-10 39.2 20.5 5.7e-05 23.3 0.6 7.7 7 2 0 7 7 7 2 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ13011.1 - 7e-10 38.3 7.6 1.6e-05 24.4 0.5 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 OAJ13011.1 - 0.00026 20.9 14.0 0.0085 16.1 0.1 6.6 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ13011.1 - 0.00069 19.5 6.4 0.08 13.0 0.1 4.8 5 0 0 5 5 5 1 Kelch motif Protamine_P2 PF00841.19 OAJ13011.1 - 0.25 11.8 3.3 0.71 10.4 3.3 1.7 1 0 0 1 1 1 0 Sperm histone P2 tRNA_int_endo PF01974.17 OAJ13012.1 - 1.8e-14 53.6 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Polysacc_deac_1 PF01522.21 OAJ13013.1 - 0.002 18.0 0.1 0.0059 16.5 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Dimer_Tnp_hAT PF05699.14 OAJ13031.1 - 2.2e-18 65.8 0.4 4.6e-18 64.8 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ13031.1 - 0.0058 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) zf-MYND PF01753.18 OAJ13031.1 - 0.015 15.3 2.4 0.035 14.2 2.4 1.6 1 0 0 1 1 1 0 MYND finger PCSK9_C1 PF18459.1 OAJ13031.1 - 0.093 12.9 1.9 0.73 10.0 0.0 2.8 3 0 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain HTH_DeoR PF08220.12 OAJ13031.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Pkinase PF00069.25 OAJ13032.1 - 3.6e-33 115.1 0.0 1.7e-28 99.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13032.1 - 1.7e-15 57.0 0.0 2.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ13032.1 - 0.00013 21.3 0.0 0.00083 18.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RAP1 PF07218.11 OAJ13032.1 - 0.063 11.6 0.2 0.097 10.9 0.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pox_ser-thr_kin PF05445.11 OAJ13032.1 - 0.34 9.8 0.1 0.5 9.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase bZIP_1 PF00170.21 OAJ13048.1 - 4.7e-07 29.8 3.6 1e-06 28.7 3.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ13048.1 - 0.0026 17.8 3.9 0.006 16.6 3.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper LysM PF01476.20 OAJ13049.1 - 2.6e-10 40.2 0.0 0.0001 22.3 0.0 2.6 2 0 0 2 2 2 2 LysM domain Retinal PF15449.6 OAJ13049.1 - 10 3.8 13.4 11 3.6 13.4 1.0 1 0 0 1 1 1 0 Retinal protein RasGEF PF00617.19 OAJ13064.1 - 1.4e-41 142.6 0.1 2.5e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ13064.1 - 5.9e-07 29.7 0.1 1.6e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 OAJ13064.1 - 0.00013 21.6 0.0 0.00033 20.3 0.0 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.21 OAJ13064.1 - 0.0072 15.8 0.0 0.017 14.6 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Aminotran_1_2 PF00155.21 OAJ13065.1 - 3.4e-36 125.2 0.0 6.5e-36 124.3 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ13065.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_MocR PF12897.7 OAJ13065.1 - 0.047 12.5 0.0 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase TLD PF07534.16 OAJ13084.1 - 7.7e-25 87.7 0.0 1.9e-21 76.7 0.0 3.1 2 1 0 2 2 2 2 TLD Glyco_hydro_3 PF00933.21 OAJ13085.1 - 2.4e-67 227.6 0.9 2.4e-67 227.6 0.9 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 OAJ13085.1 - 0.074 13.0 3.6 0.089 12.7 0.1 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain DUF4537 PF15057.6 OAJ13086.1 - 0.14 12.2 0.1 0.47 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) HTH_Tnp_Tc3_2 PF01498.18 OAJ13099.1 - 1.5e-16 60.4 3.5 4.1e-16 59.0 3.5 1.8 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 OAJ13099.1 - 5.5e-13 48.9 0.0 9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ13099.1 - 0.0079 16.8 0.7 0.0079 16.8 0.7 3.4 4 0 0 4 4 4 1 Homeodomain-like domain HTH_38 PF13936.6 OAJ13099.1 - 0.019 14.7 0.6 3 7.7 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain UDPGP PF01704.18 OAJ13100.1 - 2.1e-202 672.2 0.2 2.4e-202 672.0 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase EthD PF07110.11 OAJ13101.1 - 0.00029 21.9 0.7 0.084 14.0 0.2 2.8 2 1 0 2 2 2 2 EthD domain GATase_7 PF13537.6 OAJ13102.1 - 2.9e-11 43.3 0.0 5.3e-11 42.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAJ13102.1 - 3e-09 37.2 0.0 3.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase domain RBD PF02196.15 OAJ13102.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF1400 PF07176.11 OAJ13102.1 - 0.014 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF3700 PF12481.8 OAJ13102.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein DUF1295 PF06966.12 OAJ13117.1 - 5.2e-41 140.7 0.9 9.4e-41 139.9 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 OAJ13117.1 - 0.00043 20.3 1.5 0.00088 19.3 0.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 OAJ13117.1 - 0.0098 16.3 0.1 0.055 13.9 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 OAJ13117.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAD_binding_7 PF03441.14 OAJ13118.1 - 3.8e-73 245.3 0.6 6.2e-73 244.6 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ13118.1 - 1.2e-39 136.0 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF4543 PF15076.6 OAJ13152.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) FA_desaturase PF00487.24 OAJ13155.1 - 3.6e-13 50.0 2.8 4.9e-13 49.5 2.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase PHBC_N PF12551.8 OAJ13155.1 - 0.19 11.5 2.6 0.2 11.5 0.5 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal RVT_1 PF00078.27 OAJ13176.1 - 5.8e-24 84.8 0.0 1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ13176.1 - 1.7e-20 72.9 0.2 2.4e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ13176.1 - 5e-15 55.7 0.0 3.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13176.1 - 1.9e-14 53.5 0.0 4.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ13176.1 - 7.6e-10 39.0 0.0 2.6e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 OAJ13176.1 - 0.084 13.1 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 OAJ13195.1 - 7.1e-23 81.3 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ13195.1 - 4.3e-21 74.8 0.1 9.9e-14 51.2 0.0 2.8 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ13195.1 - 1.4e-15 57.4 0.0 1.3e-09 38.3 0.0 3.1 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13195.1 - 2e-15 56.6 0.6 3.8e-15 55.7 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ13195.1 - 1.7e-10 41.1 0.0 5.2e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ13195.1 - 0.00022 21.8 0.0 0.00067 20.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ13195.1 - 0.056 14.0 0.0 0.15 12.7 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2528 PF10800.8 OAJ13212.1 - 0.22 12.1 2.0 12 6.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) zf-CCHC_6 PF15288.6 OAJ13232.1 - 0.0004 20.2 0.5 0.00086 19.1 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 OAJ13232.1 - 0.079 12.7 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DUF2417 PF10329.9 OAJ13251.1 - 4.3e-13 49.2 0.0 1.3e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 Region of unknown function (DUF2417) DUF3951 PF13131.6 OAJ13251.1 - 0.017 15.3 2.8 1.4 9.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF2070 PF09843.9 OAJ13251.1 - 4.1 5.6 9.7 6.1 5.0 9.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CLPTM1 PF05602.12 OAJ13252.1 - 5.3e-100 335.4 0.0 1.5e-96 324.0 0.0 2.4 1 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 OAJ13252.1 - 5.7e-09 35.6 1.0 2.3e-07 30.5 0.5 2.5 2 0 0 2 2 2 1 PQ loop repeat ER_lumen_recept PF00810.18 OAJ13252.1 - 0.13 13.1 2.5 0.32 11.8 2.5 1.7 1 1 0 1 1 1 0 ER lumen protein retaining receptor ECH_2 PF16113.5 OAJ13269.1 - 2.9e-76 257.1 1.3 5.7e-73 246.3 1.3 3.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 OAJ13269.1 - 1.4e-17 63.8 1.9 9.1e-17 61.2 0.1 2.5 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase PRELI PF04707.14 OAJ13270.1 - 1.8e-18 66.8 0.9 3.5e-07 30.2 0.1 3.3 2 1 0 2 2 2 2 PRELI-like family Pkinase PF00069.25 OAJ13271.1 - 9.3e-40 136.6 0.0 8.1e-22 77.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13271.1 - 2.3e-19 69.7 0.0 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ13271.1 - 1.6e-07 31.0 0.0 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 OAJ13271.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 OAJ13286.1 - 1.4e-36 126.9 0.1 2.4e-36 126.2 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ13286.1 - 8.5e-17 61.3 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIIA PF03153.13 OAJ13286.1 - 1.4 8.8 21.9 2.1 8.2 21.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 OAJ13287.1 - 0.0083 15.8 1.8 0.011 15.4 1.8 1.1 1 0 0 1 1 1 1 FAM176 family CDC45 PF02724.14 OAJ13287.1 - 0.039 12.3 0.8 0.041 12.2 0.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OAJ13287.1 - 0.066 12.1 0.4 0.06 12.2 0.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2457 PF10446.9 OAJ13287.1 - 0.75 8.9 14.2 1 8.4 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BNIP2 PF12496.8 OAJ13287.1 - 1.6 9.2 10.8 2.2 8.7 10.8 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 GCIP PF13324.6 OAJ13287.1 - 1.7 8.2 7.1 2.3 7.8 7.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Tub_N PF16322.5 OAJ13287.1 - 1.7 9.0 7.2 2.3 8.6 7.2 1.2 1 0 0 1 1 1 0 Tubby N-terminal RRN3 PF05327.11 OAJ13287.1 - 3 6.3 4.2 3.6 6.0 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 OAJ13287.1 - 4.3 5.0 4.7 5.2 4.7 4.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF3128 PF11326.8 OAJ13288.1 - 0.0022 18.3 0.8 0.0033 17.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 OAJ13288.1 - 0.0065 16.7 1.8 0.066 13.5 0.1 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 OAJ13288.1 - 0.017 15.2 2.0 0.024 14.7 2.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 OAJ13288.1 - 0.024 14.9 1.2 0.039 14.2 1.2 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.9 OAJ13288.1 - 0.032 14.5 0.8 0.05 13.9 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 OAJ13288.1 - 1.1 9.5 7.8 5.1 7.3 8.2 1.9 1 1 1 2 2 2 0 CHCH domain UQ_con PF00179.26 OAJ13289.1 - 7.8e-43 145.5 0.0 8.8e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ13289.1 - 0.008 15.9 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B HTH_57 PF18679.1 OAJ13289.1 - 0.17 12.2 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 ThcOx helix turn helix domain TFIID_NTD2 PF04494.15 OAJ13290.1 - 1.2e-29 103.2 0.0 3.3e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain WD40 PF00400.32 OAJ13290.1 - 4.2e-17 62.2 2.6 2.3e-06 28.2 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat LisH PF08513.11 OAJ13290.1 - 0.0071 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 LisH NUC153 PF08159.12 OAJ13305.1 - 1.5e-10 40.7 7.1 1.4e-09 37.5 0.0 3.6 3 0 0 3 3 3 1 NUC153 domain TMEM51 PF15345.6 OAJ13305.1 - 0.011 15.6 1.1 0.011 15.6 1.1 2.5 4 0 0 4 4 4 0 Transmembrane protein 51 Ank_2 PF12796.7 OAJ13308.1 - 5.1e-51 171.2 0.0 1.9e-19 70.1 0.0 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ13308.1 - 1.7e-35 120.9 1.6 1.7e-12 47.5 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ13308.1 - 1.1e-33 114.8 1.0 8.9e-11 41.8 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ13308.1 - 2.1e-22 76.8 0.1 0.00021 21.4 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 OAJ13308.1 - 1.8e-18 66.1 0.1 0.00061 20.1 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 OAJ13308.1 - 0.019 15.1 1.4 0.073 13.2 0.4 2.1 2 0 0 2 2 2 0 FYVE zinc finger CMS1 PF14617.6 OAJ13308.1 - 0.061 12.7 0.0 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AMP-binding PF00501.28 OAJ13328.1 - 4.1e-18 65.2 0.0 5.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Dicer_dimer PF03368.14 OAJ13329.1 - 1.3e-19 70.1 0.1 3e-19 69.0 0.1 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 OAJ13329.1 - 5.2e-14 52.5 0.0 1.1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SR-25 PF10500.9 OAJ13329.1 - 0.29 10.7 2.9 0.49 10.0 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_Ag35 PF03286.14 OAJ13351.1 - 0.025 14.4 9.4 0.056 13.2 9.4 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5419 PF17441.2 OAJ13351.1 - 0.095 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5419) GEMIN8 PF15348.6 OAJ13351.1 - 0.17 12.2 4.0 0.37 11.1 4.0 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DNA_pol_phi PF04931.13 OAJ13351.1 - 0.6 8.2 7.4 0.95 7.5 7.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi DHHW PF14286.6 OAJ13351.1 - 1.1 8.4 4.6 1.8 7.8 4.6 1.2 1 0 0 1 1 1 0 DHHW protein CENP-B_dimeris PF09026.10 OAJ13351.1 - 1.4 9.4 6.0 3.4 8.1 6.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S64 PF08192.11 OAJ13351.1 - 3.9 5.8 12.2 5.6 5.3 12.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 DsbG_N PF18257.1 OAJ13376.1 - 0.039 14.1 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal Palm_thioest PF02089.15 OAJ13376.1 - 0.087 12.6 0.1 0.27 11.0 0.0 1.6 1 1 1 2 2 2 0 Palmitoyl protein thioesterase Gp_dh_C PF02800.20 OAJ13377.1 - 4.4e-69 231.1 0.0 5.9e-69 230.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 OAJ13377.1 - 2e-38 130.8 0.1 4.1e-38 129.8 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PalH PF08733.10 OAJ13390.1 - 0.00014 21.0 4.3 0.00023 20.3 4.3 1.3 1 0 0 1 1 1 1 PalH/RIM21 Aft1_HRA PF11786.8 OAJ13390.1 - 0.28 11.6 17.4 0.031 14.6 7.2 2.9 2 1 0 2 2 2 0 Aft1 HRA domain His_Phos_1 PF00300.22 OAJ13391.1 - 1.1e-19 71.0 0.1 3.1e-12 46.6 0.0 2.5 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) DUF4218 PF13960.6 OAJ13419.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Ytp1 PF10355.9 OAJ13447.1 - 8.3e-96 320.4 1.4 1.3e-95 319.8 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ13447.1 - 2e-14 53.2 0.5 2e-14 53.2 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Peptidase_M43 PF05572.13 OAJ13448.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 OAJ13448.1 - 0.0011 18.6 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 OAJ13448.1 - 0.0012 19.4 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ13448.1 - 0.0035 17.5 0.0 0.0078 16.4 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ13448.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 OAJ13448.1 - 0.044 13.6 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 OAJ13449.1 - 5.7e-12 45.8 0.0 9.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ13449.1 - 9.1e-07 29.4 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ13449.1 - 0.0011 19.2 0.2 0.0021 18.2 0.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAJ13449.1 - 0.0091 15.7 1.3 0.026 14.2 0.2 2.1 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ13449.1 - 0.025 14.4 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 OAJ13449.1 - 0.042 13.1 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M54 PF07998.11 OAJ13449.1 - 0.19 11.7 0.0 0.68 9.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M54 DUF4350 PF14258.6 OAJ13466.1 - 0.01 16.2 0.2 0.12 12.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Myc_N PF01056.18 OAJ13466.1 - 0.014 15.3 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 OAJ13466.1 - 2.1 7.6 3.5 3.3 6.9 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein FSAP_sig_propep PF03032.15 OAJ13466.1 - 2.4 8.3 4.2 4.3 7.4 4.2 1.5 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide CENP-B_dimeris PF09026.10 OAJ13466.1 - 3.9 7.9 9.2 10 6.6 9.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain WW PF00397.26 OAJ13467.1 - 4.3e-07 29.9 3.2 8.2e-07 29.0 3.2 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 OAJ13467.1 - 5e-05 23.5 40.7 5e-05 23.5 40.7 3.6 1 1 2 3 3 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CYSTM PF12734.7 OAJ13467.1 - 0.051 13.9 1.0 0.051 13.9 1.0 7.7 4 1 0 4 4 3 0 Cysteine-rich TM module stress tolerance RR_TM4-6 PF06459.12 OAJ13467.1 - 0.06 13.2 8.7 0.079 12.8 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 OAJ13467.1 - 0.86 8.7 6.1 1.2 8.3 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 OAJ13467.1 - 1.3 7.8 9.9 1.5 7.6 9.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.16 OAJ13467.1 - 1.9 8.5 2.8 2.8 8.0 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 OAJ13467.1 - 3.1 6.5 9.8 4.4 6.0 9.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4692 PF15763.5 OAJ13467.1 - 3.4 8.1 8.6 5.2 7.5 8.6 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) ATP-synt_E PF05680.12 OAJ13467.1 - 3.6 8.0 8.4 5.4 7.4 8.4 1.2 1 0 0 1 1 1 0 ATP synthase E chain CSRNP_N PF16019.5 OAJ13467.1 - 4.3 7.2 13.6 6.4 6.6 13.6 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RPEL PF02755.15 OAJ13468.1 - 2.3e-15 55.7 13.3 3e-06 26.7 1.6 3.9 4 0 0 4 4 4 3 RPEL repeat PilP PF04351.13 OAJ13468.1 - 0.39 10.7 5.4 1.6 8.7 2.0 2.4 1 1 2 3 3 3 0 Pilus assembly protein, PilP PPTA PF01239.22 OAJ13469.1 - 5.8e-40 133.9 2.0 1.2e-09 37.6 0.3 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 OAJ13469.1 - 0.0011 19.1 0.2 1.6 9.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ13469.1 - 0.03 15.1 0.5 1 10.4 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1769 PF08588.10 OAJ13484.1 - 2.1e-05 24.6 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Cys_Met_Meta_PP PF01053.20 OAJ13485.1 - 4e-21 75.0 0.0 2.5e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ13485.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SelK_SelG PF10961.8 OAJ13485.1 - 0.84 10.3 3.8 3.3 8.4 3.8 2.0 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Exo_endo_phos PF03372.23 OAJ13486.1 - 4.9e-06 26.2 0.0 1.5e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4078 PF13300.6 OAJ13487.1 - 1.2e-15 57.6 4.0 1.2e-15 57.6 0.9 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) RT_RNaseH PF17917.1 OAJ13502.1 - 1.7e-18 66.8 0.1 5.2e-18 65.3 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ13502.1 - 2e-14 53.8 0.0 6.3e-14 52.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ13502.1 - 2.2e-11 43.6 0.0 4.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13502.1 - 5e-09 36.1 0.4 9.5e-09 35.2 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ13502.1 - 0.0013 18.5 0.1 0.006 16.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain DUF2528 PF10800.8 OAJ13503.1 - 0.22 12.1 0.0 0.41 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) MULE PF10551.9 OAJ13516.1 - 4.7e-08 33.3 0.1 0.0016 18.8 0.0 2.4 1 1 1 2 2 2 2 MULE transposase domain SWIM PF04434.17 OAJ13516.1 - 0.0013 18.4 0.1 0.0027 17.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger CAS_CSE1 PF03378.15 OAJ13534.1 - 2.8e-08 32.7 0.3 1.7e-06 26.8 0.0 1.9 1 1 1 2 2 2 2 CAS/CSE protein, C-terminus NDC10_II PF16787.5 OAJ13573.1 - 1.5e-26 93.2 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_29 PF13551.6 OAJ13573.1 - 0.041 13.9 0.1 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_1 PF01527.20 OAJ13573.1 - 0.046 14.0 0.6 0.18 12.1 0.0 2.4 2 0 0 2 2 2 0 Transposase Sec63 PF02889.16 OAJ13591.1 - 1.3e-30 106.5 0.0 1.8e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 OAJ13591.1 - 1.7e-08 34.8 0.0 4.8e-08 33.3 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 OAJ13591.1 - 0.16 12.6 0.0 0.5 11.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Pkinase PF00069.25 OAJ13607.1 - 1.1e-43 149.6 0.0 4.4e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13607.1 - 9.8e-20 70.9 0.0 8.2e-19 67.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ13607.1 - 0.00045 20.2 0.7 0.00065 19.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ13607.1 - 0.00047 19.6 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ13607.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ13607.1 - 0.034 12.9 0.1 0.09 11.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 OAJ13607.1 - 0.17 10.8 0.0 0.17 10.8 0.0 2.3 3 0 0 3 3 3 0 Haspin like kinase domain DUF4330 PF14221.6 OAJ13624.1 - 0.059 13.6 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) NOP19 PF10863.8 OAJ13626.1 - 0.033 14.0 0.5 0.1 12.4 0.5 1.8 1 0 0 1 1 1 0 Nucleolar protein 19 NapD PF03927.13 OAJ13626.1 - 0.13 12.3 0.8 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 NapD protein Helo_like_N PF17111.5 OAJ13626.1 - 0.22 10.9 1.8 0.42 10.0 1.8 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF4218 PF13960.6 OAJ13627.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HeH PF12949.7 OAJ13668.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain DUF3136 PF11334.8 OAJ13668.1 - 0.098 12.5 0.1 0.68 9.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3136) Prp19 PF08606.11 OAJ13708.1 - 1.6e-29 101.6 1.5 3.4e-29 100.6 1.5 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 OAJ13708.1 - 9.6e-22 76.9 3.3 5.7e-05 23.8 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ13708.1 - 4.3e-14 52.6 0.1 0.027 14.8 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 OAJ13708.1 - 0.00098 19.2 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 OAJ13708.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 OAJ13708.1 - 0.021 14.2 0.1 0.051 12.9 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-NOSIP PF15906.5 OAJ13708.1 - 0.024 14.7 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF3450 PF11932.8 OAJ13708.1 - 0.72 9.1 4.1 0.13 11.5 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) RibD_C PF01872.17 OAJ13709.1 - 6.8e-34 117.4 0.0 2e-33 115.9 0.0 1.8 2 0 0 2 2 2 1 RibD C-terminal domain Sec7 PF01369.20 OAJ13709.1 - 2.1e-31 109.0 0.0 2.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Hist_deacetyl PF00850.19 OAJ13728.1 - 7.7e-83 278.5 0.0 1.2e-82 277.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAJ13728.1 - 4.2e-09 35.9 0.0 0.00021 20.5 0.0 3.3 3 0 0 3 3 3 2 Arb2 domain HTH_IclR PF09339.10 OAJ13728.1 - 0.08 12.7 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Gly_transf_sug PF04488.15 OAJ13729.1 - 2.3e-20 73.0 0.1 4e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 OAJ13729.1 - 0.047 13.0 0.6 1.6 7.9 0.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain RT_RNaseH_2 PF17919.1 OAJ13754.1 - 1e-17 64.0 0.0 1.2e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ13754.1 - 2.6e-15 56.3 0.0 5.8e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ13754.1 - 7.6e-14 51.9 0.0 2.5e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ13754.1 - 2.3e-12 46.9 0.0 3.3e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ13754.1 - 4.1e-09 36.7 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ13754.1 - 0.012 16.2 0.1 0.038 14.6 0.1 1.9 1 0 0 1 1 1 0 Aspartyl protease zf-H2C2 PF09337.10 OAJ13754.1 - 0.024 14.8 0.1 0.07 13.4 0.1 1.9 1 0 0 1 1 1 0 H2C2 zinc finger RVP PF00077.20 OAJ13754.1 - 0.14 12.4 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ13774.1 - 0.01 15.9 5.4 0.02 14.9 5.4 1.5 1 0 0 1 1 1 0 Zinc knuckle TTRAP PF14203.6 OAJ13774.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein zf-CCHC_3 PF13917.6 OAJ13774.1 - 0.046 13.7 0.7 0.098 12.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle AF-4 PF05110.13 OAJ13775.1 - 1.7 6.7 14.7 2.2 6.3 14.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Collagen PF01391.18 OAJ13786.1 - 3.9e-05 23.3 12.8 5.9e-05 22.7 12.8 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Prefoldin_2 PF01920.20 OAJ13798.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit zf-CGNR PF11706.8 OAJ13798.1 - 0.22 11.4 2.5 0.41 10.5 2.5 1.4 1 0 0 1 1 1 0 CGNR zinc finger SUD-M PF11633.8 OAJ13799.1 - 0.033 13.9 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain ADH_zinc_N_2 PF13602.6 OAJ13820.1 - 1.2e-18 68.5 0.0 4.1e-18 66.7 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ13820.1 - 3.8e-14 52.8 1.1 9.6e-14 51.5 0.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ13820.1 - 1.3e-10 41.1 0.3 1.3e-07 31.5 0.1 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ13820.1 - 0.0013 18.6 0.0 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 OAJ13820.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PALP PF00291.25 OAJ13820.1 - 0.028 13.8 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PIN_4 PF13638.6 OAJ13822.1 - 1.3e-11 44.9 0.0 1.5e-10 41.5 0.0 2.2 1 1 0 1 1 1 1 PIN domain DUF4407 PF14362.6 OAJ13823.1 - 8 5.7 9.3 1.3 8.3 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 OAJ13839.1 - 5.2e-32 111.3 0.0 1.3e-31 109.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ13839.1 - 6.1e-09 35.5 0.0 1.7e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase ABC2_membrane PF01061.24 OAJ13856.1 - 3.4e-30 105.0 17.0 4.7e-30 104.6 17.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ13856.1 - 1e-25 90.9 0.1 1.7e-25 90.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ13856.1 - 8.1e-07 29.1 0.2 0.009 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ13856.1 - 2.9e-05 23.7 0.6 0.00023 20.8 0.4 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ13856.1 - 0.00028 21.3 0.1 0.00061 20.2 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ13856.1 - 0.0012 18.8 0.2 0.0035 17.3 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ13856.1 - 0.0027 18.0 0.4 0.013 15.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 OAJ13856.1 - 0.008 16.7 0.1 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ13856.1 - 0.02 14.6 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 OAJ13856.1 - 0.082 12.8 0.1 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 OAJ13856.1 - 0.086 12.6 0.1 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 OAJ13856.1 - 0.11 12.1 1.3 0.56 9.8 0.2 2.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 OAJ13856.1 - 0.14 11.2 0.1 0.33 10.0 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein FAD_binding_8 PF08022.12 OAJ13857.1 - 5e-19 68.4 0.0 1.2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ13857.1 - 2.5e-14 53.7 0.0 3.1e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ13857.1 - 3.2e-11 43.4 4.4 3.2e-11 43.4 4.4 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Adaptin_N PF01602.20 OAJ13870.1 - 1.8e-100 337.0 10.5 3.1e-100 336.2 10.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 OAJ13870.1 - 2.3e-60 202.2 0.0 6.6e-60 200.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 OAJ13870.1 - 4.1e-60 201.7 0.1 9.5e-60 200.6 0.1 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 OAJ13870.1 - 1.8e-12 47.6 8.2 3.9e-08 33.5 0.1 3.8 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ13870.1 - 5.3e-10 39.5 7.4 0.017 15.5 0.0 5.9 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.22 OAJ13870.1 - 3.6e-07 29.9 0.2 0.046 14.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 OAJ13870.1 - 0.0032 17.6 0.2 0.051 13.7 0.0 2.8 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform ParcG PF10274.9 OAJ13870.1 - 0.024 14.8 0.8 0.99 9.5 0.0 2.7 2 1 0 2 2 2 0 Parkin co-regulated protein HEAT_EZ PF13513.6 OAJ13870.1 - 0.026 15.0 0.4 6.7 7.3 0.0 4.1 3 0 0 3 3 3 0 HEAT-like repeat Hairpins PF04877.12 OAJ13870.1 - 0.032 13.9 0.3 0.063 12.9 0.3 1.4 1 0 0 1 1 1 0 HrpZ Arm PF00514.23 OAJ13870.1 - 0.041 14.0 0.5 70 3.7 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF5071 PF16804.5 OAJ13870.1 - 0.11 12.8 1.0 7.5 6.8 0.0 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF5071) Peptidase_S9 PF00326.21 OAJ13871.1 - 4.1e-39 134.2 0.0 6.5e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAJ13871.1 - 0.0008 19.0 0.2 0.0015 18.0 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 OAJ13871.1 - 0.0012 18.5 0.4 0.005 16.5 0.3 2.0 2 1 0 2 2 2 1 Putative esterase AXE1 PF05448.12 OAJ13871.1 - 0.0058 15.3 0.4 0.57 8.8 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) PD40 PF07676.12 OAJ13871.1 - 0.018 15.0 1.0 0.058 13.4 0.1 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Dabb PF07876.12 OAJ13872.1 - 1.5e-15 57.6 0.1 1.7e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Hep_59 PF07052.11 OAJ13893.1 - 2.3e-27 95.8 0.6 2.3e-27 95.8 0.6 3.0 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 ABC_tran PF00005.27 OAJ13894.1 - 9.2e-36 123.4 0.1 8.2e-18 65.2 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 OAJ13894.1 - 1.7e-14 53.3 5.7 4.4e-14 52.0 5.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 OAJ13894.1 - 2e-09 37.2 5.1 0.001 18.6 1.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ13894.1 - 5.7e-09 36.2 3.9 0.17 11.7 0.8 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 OAJ13894.1 - 2.5e-07 30.2 3.3 2.5e-07 30.2 3.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 OAJ13894.1 - 4.1e-06 26.7 1.6 0.052 13.2 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 OAJ13894.1 - 1.1e-05 25.9 0.0 0.042 14.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 OAJ13894.1 - 1.2e-05 25.3 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Fer4_10 PF13237.6 OAJ13894.1 - 5.7e-05 23.1 8.9 0.00071 19.6 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_16 PF13191.6 OAJ13894.1 - 5.9e-05 23.5 0.0 0.077 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Fer4_6 PF12837.7 OAJ13894.1 - 7.3e-05 22.7 11.5 9.4e-05 22.3 2.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.6 OAJ13894.1 - 0.00011 22.4 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ13894.1 - 0.00016 21.4 0.2 0.51 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_7 PF12838.7 OAJ13894.1 - 0.00043 20.8 8.7 0.0014 19.2 0.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_24 PF13479.6 OAJ13894.1 - 0.00081 19.2 0.1 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ13894.1 - 0.00087 19.5 0.3 0.5 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 OAJ13894.1 - 0.0011 18.9 1.1 0.098 12.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 OAJ13894.1 - 0.0013 18.3 0.9 0.015 14.9 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 OAJ13894.1 - 0.0016 19.0 5.4 0.035 14.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ13894.1 - 0.0016 18.8 0.0 0.4 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 OAJ13894.1 - 0.0022 17.7 1.3 0.27 10.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 OAJ13894.1 - 0.0029 17.6 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_2 PF12797.7 OAJ13894.1 - 0.0037 17.3 1.3 0.0037 17.3 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain TsaE PF02367.17 OAJ13894.1 - 0.0038 17.2 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_21 PF14697.6 OAJ13894.1 - 0.0049 17.0 12.9 0.011 15.8 12.9 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.11 OAJ13894.1 - 0.0051 16.6 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 1 Virulence-associated protein E NB-ARC PF00931.22 OAJ13894.1 - 0.0067 15.7 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain SbcCD_C PF13558.6 OAJ13894.1 - 0.0077 16.5 0.0 5.7 7.2 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.6 OAJ13894.1 - 0.0082 17.1 0.3 0.0082 17.1 0.3 2.6 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain AAA_28 PF13521.6 OAJ13894.1 - 0.01 16.1 2.0 1.5 9.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 OAJ13894.1 - 0.01 16.4 0.1 3.1 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 OAJ13894.1 - 0.012 15.7 11.8 0.042 14.0 12.1 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ13894.1 - 0.022 15.2 4.4 0.08 13.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 OAJ13894.1 - 0.022 15.3 0.1 0.022 15.3 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.6 OAJ13894.1 - 0.027 14.5 0.4 13 5.9 0.1 3.2 2 1 1 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 OAJ13894.1 - 0.047 13.4 0.4 9 5.9 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase AAA_30 PF13604.6 OAJ13894.1 - 0.12 12.1 1.6 4.4 7.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 OAJ13894.1 - 0.23 11.4 0.9 2.6 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 OAJ13894.1 - 0.37 10.9 2.5 22 5.1 0.1 3.0 3 1 0 3 3 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 OAJ13894.1 - 0.7 9.8 2.6 6.7 6.6 0.1 3.2 4 0 0 4 4 3 0 NTPase Fer4_4 PF12800.7 OAJ13894.1 - 2.5 8.8 14.6 0.42 11.2 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain LSM PF01423.22 OAJ13895.1 - 5.1e-11 42.1 0.0 8.5e-11 41.4 0.0 1.4 1 1 0 1 1 1 1 LSM domain DUF5440 PF17509.2 OAJ13895.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5440) AT_hook PF02178.19 OAJ13896.1 - 0.0016 18.0 16.8 0.048 13.6 4.1 2.8 2 0 0 2 2 2 2 AT hook motif RrnaAD PF00398.20 OAJ13896.1 - 0.0029 16.7 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Glyco_hydro_63 PF03200.16 OAJ13913.1 - 6.4e-10 38.4 3.3 2.1e-07 30.1 0.3 4.2 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Methyltransf_16 PF10294.9 OAJ13913.1 - 6.1e-08 32.6 0.0 0.0043 16.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Exo_endo_phos PF03372.23 OAJ13931.1 - 5.7e-09 35.8 0.3 1.9e-08 34.1 0.3 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_1 PF00515.28 OAJ13932.1 - 8.6e-29 98.2 29.4 4.2e-05 23.2 0.3 13.8 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ13932.1 - 2.5e-24 83.4 70.6 0.00012 21.9 1.4 18.9 20 0 0 20 20 19 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ13932.1 - 4.2e-24 82.7 16.6 0.017 15.3 0.0 14.9 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ13932.1 - 1.1e-19 69.4 94.2 0.00013 22.5 0.4 19.0 14 3 5 19 19 18 7 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ13932.1 - 6.5e-18 64.1 25.1 0.00016 21.3 0.3 10.8 12 1 1 13 13 13 4 TPR repeat TPR_17 PF13431.6 OAJ13932.1 - 1.2e-16 59.7 23.6 0.022 15.1 0.1 12.9 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ13932.1 - 2.2e-12 47.4 121.3 0.00016 22.3 2.1 18.3 15 4 0 17 17 17 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ13932.1 - 2.4e-10 40.5 74.1 2.2e-09 37.5 2.5 13.4 14 2 2 16 16 16 5 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ13932.1 - 4.6e-10 39.9 72.1 0.00087 19.8 1.5 12.9 11 3 2 14 14 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ13932.1 - 1.1e-08 35.1 41.6 0.0078 16.8 0.0 13.8 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ13932.1 - 5.6e-08 32.3 28.6 0.38 10.9 0.1 10.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ13932.1 - 1.6e-05 24.6 24.1 0.073 13.0 0.1 8.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ13932.1 - 0.0026 17.9 60.7 0.46 10.7 1.4 12.8 12 2 2 14 14 12 3 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ13932.1 - 0.0039 17.3 9.1 0.68 10.0 0.8 5.6 5 0 0 5 5 4 1 Domain of Unknown Function (DUF3856) SNAP PF14938.6 OAJ13932.1 - 0.0044 16.5 4.5 0.0044 16.5 4.5 5.2 5 0 0 5 5 5 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 OAJ13932.1 - 0.0086 16.3 27.9 0.027 14.7 0.9 7.8 7 1 2 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 OAJ13932.1 - 0.038 14.1 0.1 0.16 12.1 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat FAT PF02259.23 OAJ13932.1 - 0.13 11.4 8.8 1.5 8.0 0.9 4.6 3 1 1 4 4 4 0 FAT domain ChAPs PF09295.10 OAJ13932.1 - 0.21 10.5 3.5 5.8 5.8 0.0 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 OAJ13932.1 - 0.26 11.6 34.8 1.7 9.1 0.2 8.1 5 3 1 7 7 6 0 Tetratricopeptide repeat SLX9 PF15341.6 OAJ13932.1 - 2.7 8.4 6.0 4.1 7.8 0.5 3.6 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 zf-SNAP50_C PF12251.8 OAJ13950.1 - 6.5e-08 32.5 0.0 1.5e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal SMC_Nse1 PF07574.13 OAJ13951.1 - 4.3e-26 92.0 0.1 8.3e-24 84.5 0.1 2.3 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 OAJ13951.1 - 3.9e-05 23.9 8.0 6.4e-05 23.2 8.0 1.4 1 0 0 1 1 1 1 RING-like domain Myc_N PF01056.18 OAJ13951.1 - 0.0012 18.8 1.9 0.0018 18.3 1.9 1.2 1 0 0 1 1 1 1 Myc amino-terminal region CDC45 PF02724.14 OAJ13951.1 - 0.038 12.3 2.5 0.045 12.0 2.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 OAJ13951.1 - 0.38 10.5 7.0 0.69 9.7 7.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 OAJ13951.1 - 0.44 9.8 11.8 0.86 8.9 11.9 1.5 1 1 0 1 1 1 0 NOA36 protein SURF2 PF05477.11 OAJ13951.1 - 0.76 9.4 5.3 1.1 8.9 5.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PBP1_TM PF14812.6 OAJ13951.1 - 0.94 9.9 18.7 0.088 13.2 11.7 2.5 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FANCL_C PF11793.8 OAJ13951.1 - 1.8 8.8 5.5 8 6.7 4.9 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain DNA_pol_phi PF04931.13 OAJ13951.1 - 3.4 5.7 4.9 4.4 5.3 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-CCHC PF00098.23 OAJ13952.1 - 6.4e-05 22.9 1.7 0.00016 21.6 1.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ13952.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_5 PF14787.6 OAJ13952.1 - 0.065 13.0 1.0 0.15 11.8 1.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OAJ13952.1 - 0.14 12.0 1.0 0.27 11.1 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Copper-fist PF00649.18 OAJ13952.1 - 0.34 10.4 1.2 0.85 9.2 1.2 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain RWD PF05773.22 OAJ13973.1 - 3.5e-19 69.2 0.2 5.8e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 OAJ13973.1 - 7.1e-06 26.4 9.3 3.1e-05 24.4 9.3 2.1 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF3410 PF11890.8 OAJ13973.1 - 0.22 11.3 3.7 7.3 6.5 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3410) Frag1 PF10277.9 OAJ13974.1 - 2.1e-26 92.8 18.3 2.4e-26 92.7 18.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF1345 PF07077.11 OAJ13974.1 - 0.47 10.1 8.0 1.3 8.7 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Phage_holin_3_6 PF07332.11 OAJ13974.1 - 0.6 10.2 7.2 5.5 7.1 1.2 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MIG-14_Wnt-bd PF06664.12 OAJ13974.1 - 0.74 9.0 13.4 0.89 8.7 7.5 2.1 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion Git3 PF11710.8 OAJ13974.1 - 2 8.2 14.0 0.7 9.6 0.1 3.1 2 2 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 Peptidase_M50B PF13398.6 OAJ13974.1 - 2.3 7.8 16.0 7.3 6.2 0.2 3.0 2 1 1 3 3 3 0 Peptidase M50B-like Glyco_hydro_45 PF02015.16 OAJ13993.1 - 1.3e-12 48.1 2.0 1.7e-12 47.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Colipase PF01114.18 OAJ13993.1 - 2.2 8.0 5.0 0.26 11.0 0.4 1.8 2 0 0 2 2 2 0 Colipase, N-terminal domain Glyco_hydro_45 PF02015.16 OAJ13995.1 - 1.8e-51 175.0 7.0 2.1e-51 174.8 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NIPSNAP PF07978.13 OAJ14030.1 - 1.5e-37 127.9 2.4 6.8e-30 103.3 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP DUF445 PF04286.12 OAJ14032.1 - 0.062 13.1 0.0 0.071 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4692 PF15763.5 OAJ14032.1 - 0.088 13.3 0.2 0.11 13.0 0.2 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Spt5_N PF11942.8 OAJ14032.1 - 1.5 9.9 8.9 0.15 13.1 4.0 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_85 PF03644.13 OAJ14033.1 - 3.5e-56 190.8 0.0 4.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Acyl-CoA_dh_1 PF00441.24 OAJ14034.1 - 0.093 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-C2H2 PF00096.26 OAJ14073.1 - 0.00029 21.1 9.2 0.00079 19.7 1.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ14073.1 - 0.0021 18.4 3.6 0.0021 18.4 3.6 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ14073.1 - 0.013 16.2 14.6 0.11 13.4 1.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger CAP_N PF01213.19 OAJ14092.1 - 2.9 7.3 8.9 0.12 11.8 1.0 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Peptidase_M50B PF13398.6 OAJ14114.1 - 4.8e-56 189.6 15.1 6e-56 189.2 15.1 1.0 1 0 0 1 1 1 1 Peptidase M50B-like HATPase_c PF02518.26 OAJ14115.1 - 5.3e-29 101.0 0.0 1.4e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ14115.1 - 4.4e-25 88.0 0.0 3.5e-24 85.1 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ14115.1 - 4.7e-20 71.4 0.1 1.4e-19 69.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 OAJ14115.1 - 6.8e-19 68.0 1.2 1.3e-18 67.1 0.4 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 OAJ14115.1 - 2.6e-16 59.8 1.0 2.5e-07 30.9 0.0 4.8 4 0 0 4 4 4 3 PAS fold PAS PF00989.25 OAJ14115.1 - 6.7e-11 42.2 0.0 0.013 15.5 0.0 4.6 4 0 0 4 4 4 2 PAS fold PAS_9 PF13426.7 OAJ14115.1 - 9.8e-08 32.2 0.0 1.8e-06 28.1 0.0 3.2 4 0 0 4 4 4 1 PAS domain HATPase_c_3 PF13589.6 OAJ14115.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_31 PF13614.6 OAJ14115.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain WH2 PF02205.20 OAJ14175.1 - 0.00069 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 WH2 motif EFG_C PF00679.24 OAJ14175.1 - 0.0098 15.9 0.0 0.024 14.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor G C-terminus Bacteriocin_IIc PF10439.9 OAJ14175.1 - 0.076 13.1 7.1 0.18 11.9 7.1 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Plasmodium_Vir PF05795.11 OAJ14175.1 - 0.36 10.2 2.3 0.5 9.7 2.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3583 PF12126.8 OAJ14175.1 - 2.3 7.6 5.4 4.1 6.8 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) F-box-like PF12937.7 OAJ14176.1 - 2.3e-09 37.0 0.3 5.4e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ14176.1 - 1.8e-07 30.8 0.1 5.1e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain fn3_5 PF06280.12 OAJ14177.1 - 4.6e-09 37.0 0.0 8.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain DHHC PF01529.20 OAJ14196.1 - 2.9e-31 108.3 13.0 5.9e-31 107.4 13.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_2 PF12796.7 OAJ14196.1 - 3.1e-24 85.4 0.2 1.5e-14 54.4 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ14196.1 - 1.1e-19 70.5 5.6 5e-08 33.3 0.2 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ14196.1 - 1.4e-18 65.0 3.0 0.00032 20.9 0.1 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 OAJ14196.1 - 5.8e-17 61.5 3.2 0.0014 18.9 0.0 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAJ14196.1 - 4.3e-13 49.1 11.4 0.0004 20.7 0.2 6.2 7 0 0 7 7 7 3 Ankyrin repeat vMSA PF00695.19 OAJ14196.1 - 0.31 10.1 8.1 0.57 9.2 8.1 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pet127 PF08634.10 OAJ14197.1 - 5.5e-103 344.2 0.2 7.4e-103 343.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 rve PF00665.26 OAJ14219.1 - 6.9e-07 29.5 0.0 1.9e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 OAJ14219.1 - 0.013 15.3 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain T3SS_needle_F PF09392.10 OAJ14219.1 - 0.11 12.7 0.2 1 9.6 0.2 2.3 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CcmD PF04995.14 OAJ14244.1 - 0.19 11.9 0.6 0.36 11.0 0.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Pox_Ag35 PF03286.14 OAJ14244.1 - 4.9 6.9 9.1 0.43 10.3 3.9 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein WD40 PF00400.32 OAJ14245.1 - 1.5e-35 120.5 11.1 2.7e-07 31.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ14245.1 - 1.8e-10 40.9 0.1 0.016 15.5 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ14245.1 - 0.0028 16.2 0.0 0.59 8.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain VID27 PF08553.10 OAJ14245.1 - 0.12 11.4 0.1 0.24 10.4 0.1 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain LRR_4 PF12799.7 OAJ14267.1 - 0.0003 21.1 1.3 9.3 6.8 0.0 5.2 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ14267.1 - 0.0087 16.0 6.0 2.1 8.6 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 OAJ14267.1 - 0.021 15.3 3.8 36 5.5 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.7 OAJ14267.1 - 0.029 14.3 0.4 0.094 12.6 0.4 1.9 1 1 0 1 1 1 0 F-box-like SDA1 PF05285.12 OAJ14267.1 - 0.031 13.7 0.2 0.031 13.7 0.2 2.2 2 0 0 2 2 2 0 SDA1 LRR_8 PF13855.6 OAJ14267.1 - 0.032 14.0 0.8 8.1 6.3 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat BUD22 PF09073.10 OAJ14267.1 - 1.3 8.3 22.2 1.7 7.9 6.1 2.2 2 0 0 2 2 2 0 BUD22 Polysacc_deac_1 PF01522.21 OAJ14268.1 - 8.6e-23 80.6 0.0 1.6e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 OAJ14268.1 - 0.13 11.9 0.0 0.39 10.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) GST_N PF02798.20 OAJ14269.1 - 2.1e-12 47.2 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ14269.1 - 3.6e-12 46.5 0.0 6.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ14269.1 - 1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ14269.1 - 1.5e-09 37.9 0.1 2.5e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ14269.1 - 3e-09 37.0 0.0 4.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ14269.1 - 6.9e-08 32.4 0.1 1.5e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-BED PF02892.15 OAJ14287.1 - 0.19 11.7 0.2 0.43 10.6 0.2 1.5 1 0 0 1 1 1 0 BED zinc finger RRM_1 PF00076.22 OAJ14292.1 - 5.9e-33 112.5 0.0 4.1e-17 61.8 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ14292.1 - 0.00038 20.5 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 OAJ14292.1 - 0.0008 19.0 0.0 0.37 10.4 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 OAJ14292.1 - 0.083 13.1 0.0 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 OAJ14292.1 - 0.086 12.5 0.2 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain cwf18 PF08315.12 OAJ14293.1 - 1.8e-29 103.1 8.6 2.5e-29 102.7 8.6 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SNF5 PF04855.12 OAJ14294.1 - 3e-17 63.2 0.0 3e-17 63.2 0.0 4.4 4 1 1 5 5 5 1 SNF5 / SMARCB1 / INI1 Proteasome PF00227.26 OAJ14295.1 - 5.2e-33 114.1 0.0 8.2e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit NTP_transf_2 PF01909.23 OAJ14325.1 - 2.8e-07 30.8 0.0 6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain SDA1 PF05285.12 OAJ14325.1 - 9.7 5.5 9.9 2.2 7.6 3.7 2.1 2 0 0 2 2 2 0 SDA1 MatP_C PF17414.2 OAJ14326.1 - 0.056 13.7 9.1 0.55 10.5 0.9 2.6 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Kinase-like PF14531.6 OAJ14326.1 - 0.056 12.7 2.2 0.1 11.9 2.2 1.3 1 0 0 1 1 1 0 Kinase-like Hrs_helical PF12210.8 OAJ14326.1 - 0.19 12.3 8.8 0.63 10.6 1.6 2.5 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate SPATA1_C PF15743.5 OAJ14326.1 - 1.8 8.6 22.0 0.52 10.4 2.7 2.6 2 1 1 3 3 3 0 Spermatogenesis-associated C-terminus DUF1664 PF07889.12 OAJ14326.1 - 2.5 8.2 7.6 7.5 6.6 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 OAJ14326.1 - 4.1 5.8 16.9 7.2 5.0 16.9 1.3 1 1 0 1 1 1 0 Macoilin family CotH PF08757.11 OAJ14326.1 - 5.7 6.4 7.1 0.36 10.3 1.3 1.7 2 0 0 2 2 2 0 CotH kinase protein RNA_pol_Rpb6 PF01192.22 OAJ14365.1 - 0.0084 16.0 0.0 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb6 CAP PF00188.26 OAJ14365.1 - 0.02 15.7 0.1 0.059 14.2 0.1 1.8 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF659 PF04937.15 OAJ14365.1 - 0.051 13.4 0.2 0.15 12.0 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 OAJ14365.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region SIS PF01380.22 OAJ14369.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 SIS domain Kazal_2 PF07648.15 OAJ14369.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Kinesin PF00225.23 OAJ14391.1 - 4.7e-98 328.2 5.2 5.3e-53 180.1 0.0 4.1 4 0 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ14391.1 - 2e-22 79.7 0.1 3.7e-20 72.4 0.0 3.7 3 0 0 3 3 3 1 Microtubule binding Macoilin PF09726.9 OAJ14391.1 - 0.00021 20.0 5.6 0.00021 20.0 5.6 6.9 3 2 2 6 6 6 1 Macoilin family Spc7 PF08317.11 OAJ14391.1 - 0.00027 19.9 10.5 0.00027 19.9 10.5 11.9 5 2 6 12 12 12 4 Spc7 kinetochore protein ADH_zinc_N_2 PF13602.6 OAJ14408.1 - 6.4e-18 66.1 0.0 1.3e-17 65.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 OAJ14408.1 - 1.8e-15 57.0 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DeoRC PF00455.22 OAJ14408.1 - 0.015 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 DeoR C terminal sensor domain ADH_N PF08240.12 OAJ14408.1 - 0.078 12.9 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ14408.1 - 0.15 12.0 0.0 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase SpoV PF08183.11 OAJ14408.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Stage V sporulation protein family DUF5020 PF16412.5 OAJ14409.1 - 0.037 13.9 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) His_biosynth PF00977.21 OAJ14410.1 - 2.5e-35 122.0 0.0 3.2e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 OAJ14410.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family LtrA PF06772.11 OAJ14451.1 - 1.5e-31 109.9 31.5 3e-16 59.6 22.1 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) CDV3 PF15359.6 OAJ14451.1 - 0.42 11.1 10.2 4.2 7.9 7.4 2.9 2 1 1 3 3 3 0 Carnitine deficiency-associated protein 3 Retrotrans_gag PF03732.17 OAJ14473.1 - 0.045 14.0 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein RVT_1 PF00078.27 OAJ14474.1 - 5.2e-24 85.0 0.0 8.9e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ14474.1 - 2e-13 50.2 0.0 3.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ14474.1 - 0.00083 20.0 0.1 0.0022 18.6 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ14474.1 - 0.034 14.7 0.0 0.088 13.4 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP PF00077.20 OAJ14474.1 - 0.068 13.5 0.0 0.39 11.1 0.0 2.2 2 1 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 OAJ14474.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ14476.1 - 1.7e-10 41.1 0.0 2.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ14476.1 - 3.1e-05 23.9 0.0 5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ14477.1 - 4.7e-13 49.0 0.3 9.5e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 OAJ14477.1 - 8.4e-10 38.9 0.0 3.5e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ14477.1 - 1.6e-09 38.0 0.0 3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ14477.1 - 5.2e-05 23.2 0.3 0.0002 21.4 0.0 2.0 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ14477.1 - 0.0035 17.5 0.0 0.0089 16.2 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Ubiq_cyt_C_chap PF03981.12 OAJ14500.1 - 5.5e-29 101.1 0.1 2.4e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Aminotran_1_2 PF00155.21 OAJ14501.1 - 1.6e-43 149.3 0.0 6.5e-43 147.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Gpi16 PF04113.14 OAJ14502.1 - 6.5e-99 331.9 0.0 1.2e-48 166.0 0.0 3.9 3 1 0 3 3 3 3 Gpi16 subunit, GPI transamidase component GalP_UDP_transf PF01087.22 OAJ14525.1 - 1.9e-60 204.5 0.1 2.8e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 OAJ14525.1 - 7.4e-42 142.9 0.0 2.4e-21 76.2 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 OAJ14525.1 - 0.075 11.8 0.0 6.7 5.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) GP57 PF17594.2 OAJ14525.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 Rpn3_C PF08375.11 OAJ14526.1 - 1.2e-25 89.6 1.2 2.4e-25 88.7 1.2 1.4 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 OAJ14526.1 - 1.5e-18 67.3 0.2 2.8e-18 66.3 0.1 1.5 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 OAJ14526.1 - 0.048 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family WD40 PF00400.32 OAJ14527.1 - 0.00091 20.0 0.5 20 6.3 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat AT_hook PF02178.19 OAJ14527.1 - 0.00092 18.8 90.7 2.3 8.4 6.9 8.5 7 0 0 7 7 7 7 AT hook motif SSB PF00436.25 OAJ14528.1 - 3.1e-14 52.9 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family ParA PF10609.9 OAJ14557.1 - 2.8e-65 220.2 0.1 5.8e-33 114.4 0.0 3.1 3 0 0 3 3 3 3 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ14557.1 - 3.2e-10 40.1 0.2 2.4e-08 34.1 0.2 2.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 OAJ14557.1 - 2.4e-06 27.6 0.1 8.7e-05 22.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 OAJ14557.1 - 0.0031 16.8 0.0 0.023 14.0 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 OAJ14557.1 - 0.0034 17.0 0.0 0.0094 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 OAJ14557.1 - 0.0036 17.1 0.4 0.36 10.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 OAJ14557.1 - 0.048 12.8 0.6 0.26 10.4 0.1 2.2 2 1 1 3 3 3 0 Anion-transporting ATPase Fer4_NifH PF00142.18 OAJ14557.1 - 0.081 12.4 0.0 0.17 11.3 0.1 1.4 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PIRT PF15099.6 OAJ14578.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family MarB PF13999.6 OAJ14578.1 - 0.074 12.9 0.0 3 7.7 0.0 2.7 2 0 0 2 2 2 0 MarB protein Vma12 PF11712.8 OAJ14578.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cutinase PF01083.22 OAJ14580.1 - 8.3e-22 78.0 0.0 1.1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ14580.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 OAJ14580.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 OAJ14580.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain WD40 PF00400.32 OAJ14581.1 - 1.2e-16 60.8 14.4 0.0014 19.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ14581.1 - 6.8e-10 39.1 0.0 0.11 12.8 0.0 5.8 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ14581.1 - 3.3e-06 26.3 0.3 1.6e-05 24.0 0.2 2.0 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pro_isomerase PF00160.21 OAJ14603.1 - 9.2e-46 156.0 0.1 1e-45 155.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Choline_transpo PF04515.12 OAJ14604.1 - 3.1e-78 263.3 25.9 3.1e-78 263.3 25.9 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter Pex14_N PF04695.13 OAJ14604.1 - 0.041 14.6 3.5 0.12 13.0 3.5 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSF_DNA-bind PF00447.17 OAJ14605.1 - 1.6e-19 70.3 0.0 1.7e-18 67.0 0.0 2.2 1 1 0 1 1 1 1 HSF-type DNA-binding Sld5 PF05916.11 OAJ14623.1 - 3.2e-17 63.0 0.0 5.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DSPn PF14671.6 OAJ14624.1 - 4e-33 114.8 0.0 5.3e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 OAJ14624.1 - 1.2e-12 47.8 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ14624.1 - 0.00024 20.7 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAJ14624.1 - 0.0078 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Fes1 PF08609.10 OAJ14624.1 - 0.19 12.6 1.1 1.2 10.1 1.1 2.4 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 COG2 PF06148.11 OAJ14624.1 - 0.38 10.8 1.5 0.75 9.9 1.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-RING_2 PF13639.6 OAJ14650.1 - 4.7e-08 33.2 11.6 7.2e-08 32.6 11.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ14650.1 - 0.00033 20.3 7.9 0.00061 19.5 7.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ14650.1 - 0.00056 19.7 9.9 0.00086 19.1 9.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ14650.1 - 0.0044 16.9 10.4 0.0067 16.4 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ14650.1 - 0.014 15.3 10.2 0.02 14.7 10.2 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ14650.1 - 0.62 10.4 9.8 1.7 9.0 9.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ14650.1 - 2.5 8.1 10.5 3.8 7.5 10.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ14650.1 - 4.3 7.3 9.7 7.3 6.5 9.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CRCB PF02537.15 OAJ14651.1 - 1.6e-24 86.0 19.1 5.9e-15 55.3 4.8 2.7 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Aldedh PF00171.22 OAJ14652.1 - 1.2e-144 482.3 0.2 1.3e-144 482.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lipid_DES PF08557.10 OAJ14652.1 - 0.22 11.1 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Chitin_synth_1 PF01644.17 OAJ14674.1 - 4.7e-67 225.0 1.6 7.3e-67 224.4 1.6 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 OAJ14674.1 - 2.5e-22 79.2 0.0 4.1e-18 65.3 0.0 2.8 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ14674.1 - 5.3e-22 77.5 0.0 1.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 OAJ14674.1 - 2e-06 27.8 0.4 2e-06 27.8 0.4 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Colicin_im PF03857.13 OAJ14675.1 - 0.056 13.4 0.2 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 Colicin immunity protein Fungal_trans PF04082.18 OAJ14702.1 - 0.0017 17.4 0.0 0.004 16.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2722 PF10846.8 OAJ14702.1 - 0.022 13.8 9.6 0.041 12.8 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 OAJ14702.1 - 0.029 13.4 4.4 0.043 12.8 4.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 OAJ14702.1 - 0.039 14.9 0.6 0.12 13.4 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CCDC53 PF10152.9 OAJ14702.1 - 0.45 10.9 4.8 0.4 11.1 1.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 OAJ14702.1 - 1.4 8.5 26.3 0.12 12.0 17.3 2.4 2 0 0 2 2 2 0 Spt20 family RAB3GAP2_N PF14655.6 OAJ14702.1 - 1.5 8.0 3.8 2.5 7.2 3.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5421 PF17458.2 OAJ14702.1 - 4.5 6.6 7.9 7 6.0 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Pex14_N PF04695.13 OAJ14702.1 - 8.4 7.0 23.0 0.24 12.1 9.5 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cpn60_TCP1 PF00118.24 OAJ14703.1 - 1.7e-143 478.8 8.7 1.9e-143 478.6 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 OAJ14703.1 - 0.068 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Glycogen_syn PF05693.13 OAJ14703.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase BLM10_N PF16547.5 OAJ14704.1 - 0.00016 21.9 1.5 0.00023 21.4 0.9 1.7 1 1 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal ArAE_2_N PF10337.9 OAJ14704.1 - 0.0081 15.2 1.2 0.0094 15.0 1.2 1.0 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal RRN3 PF05327.11 OAJ14704.1 - 0.036 12.6 1.8 0.038 12.6 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4407 PF14362.6 OAJ14704.1 - 0.046 13.1 1.2 0.056 12.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.12 OAJ14704.1 - 0.083 11.1 17.3 0.095 10.9 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ14704.1 - 2.8 6.1 11.3 3.3 5.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLX9 PF15341.6 OAJ14705.1 - 1.4e-17 64.3 3.9 2.7e-17 63.4 3.9 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Phage_int_SAM_1 PF02899.17 OAJ14725.1 - 0.029 14.7 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PikAIV_N PF18605.1 OAJ14725.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Myb_DNA-bind_3 PF12776.7 OAJ14747.1 - 5.4e-14 53.0 0.4 1.3e-13 51.7 0.4 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DEAD PF00270.29 OAJ14748.1 - 1.7e-39 135.4 0.0 2.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ14748.1 - 3.2e-24 85.4 0.0 9.1e-24 84.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ14748.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MtlR PF05068.12 OAJ14748.1 - 0.15 12.0 0.3 0.31 11.0 0.1 1.5 2 0 0 2 2 2 0 Mannitol repressor DDE_Tnp_4 PF13359.6 OAJ14749.1 - 6.9e-07 29.1 0.1 1.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ14749.1 - 1.6e-05 24.6 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Pkinase PF00069.25 OAJ14772.1 - 8.5e-43 146.6 0.0 1.2e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14772.1 - 2.8e-20 72.7 0.0 4e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14772.1 - 4.8e-06 26.1 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ14772.1 - 0.00068 19.6 0.3 0.0066 16.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ14772.1 - 0.024 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 OAJ14772.1 - 0.047 13.3 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family NitrOD2 PF18550.1 OAJ14773.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Nitrososphaera output domain 2 Dimer_Tnp_hAT PF05699.14 OAJ14774.1 - 2.8e-15 55.9 0.1 8.2e-15 54.4 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region FdhE PF04216.12 OAJ14774.1 - 5.8 6.7 6.8 0.71 9.7 0.3 2.5 3 0 0 3 3 3 0 Protein involved in formate dehydrogenase formation SHMT PF00464.19 OAJ14795.1 - 5.7e-167 555.3 0.0 6.7e-167 555.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 OAJ14795.1 - 0.006 15.9 0.1 0.011 15.0 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 OAJ14795.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Cyt-b5 PF00173.28 OAJ14796.1 - 2.1e-19 69.4 0.1 3.9e-19 68.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TspO_MBR PF03073.15 OAJ14797.1 - 7.7e-39 132.8 13.3 8.9e-39 132.6 13.3 1.0 1 0 0 1 1 1 1 TspO/MBR family DUF2776 PF10951.8 OAJ14797.1 - 0.098 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) PDH PF02153.17 OAJ14798.1 - 1.9e-13 50.0 0.0 2.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 OAJ14798.1 - 7.3e-08 32.9 0.4 1.8e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 OAJ14798.1 - 0.00014 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAJ14798.1 - 0.0002 21.4 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ14798.1 - 0.00061 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 OAJ14798.1 - 0.0017 17.8 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 OAJ14798.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ14798.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pheromone PF08015.11 OAJ14819.1 - 0.036 15.1 0.8 0.036 15.1 0.8 4.7 4 1 0 4 4 4 0 Fungal mating-type pheromone DUF2207 PF09972.9 OAJ14839.1 - 0.13 11.0 0.6 6.2 5.5 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Abhydrolase_1 PF00561.20 OAJ14840.1 - 1.6e-21 77.1 0.0 1.1e-20 74.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ14840.1 - 1.9e-16 61.3 0.9 2.4e-15 57.8 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ14840.1 - 9.8e-14 51.2 0.0 2.8e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAJ14840.1 - 2.5e-06 27.4 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 OAJ14840.1 - 0.0013 18.4 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 OAJ14840.1 - 0.0014 18.6 0.0 0.15 12.0 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 OAJ14840.1 - 0.0016 18.4 0.2 0.0086 16.0 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAJ14840.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 OAJ14840.1 - 0.035 12.8 0.0 0.06 12.0 0.0 1.3 1 0 0 1 1 1 0 Ndr family zf-C3HC4_3 PF13920.6 OAJ14841.1 - 1.5e-06 27.9 7.9 1.5e-06 27.9 7.9 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF971 PF06155.12 OAJ14841.1 - 0.49 11.1 0.0 0.49 11.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF971) zf-C2H2 PF00096.26 OAJ14841.1 - 2.6 8.7 24.2 0.13 12.7 0.5 5.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type Pkinase PF00069.25 OAJ14864.1 - 2.5e-69 233.6 0.0 5.1e-69 232.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ14864.1 - 1.6e-29 103.0 0.0 1.6e-28 99.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ14864.1 - 0.00012 21.5 0.8 2.6 7.3 0.1 3.2 3 0 0 3 3 3 3 Kinase-like RIO1 PF01163.22 OAJ14864.1 - 0.00035 20.2 0.6 0.00066 19.3 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 OAJ14864.1 - 0.0081 15.0 0.1 0.019 13.8 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ14864.1 - 0.0096 15.9 3.3 0.52 10.2 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family F-box-like PF12937.7 OAJ14887.1 - 9.9e-11 41.4 0.6 3.2e-10 39.7 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ14887.1 - 2.3e-06 27.4 0.7 6.5e-06 25.9 0.7 1.9 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 OAJ14887.1 - 0.04 14.8 0.7 1.3 10.0 0.2 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat MscS_porin PF12795.7 OAJ14888.1 - 0.0016 18.0 0.9 0.0017 17.9 0.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Sugarporin_N PF11471.8 OAJ14888.1 - 0.0041 17.0 0.2 0.0071 16.3 0.2 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension eIF3m_C_helix PF18005.1 OAJ14888.1 - 0.078 12.7 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix F-box PF00646.33 OAJ14889.1 - 1.4e-07 31.2 0.1 3e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ14889.1 - 0.0028 17.5 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ14889.1 - 0.029 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 F-box Ribosomal_L3 PF00297.22 OAJ14912.1 - 4e-17 62.3 1.2 1.1e-16 60.8 1.0 1.8 1 1 2 3 3 3 1 Ribosomal protein L3 Ribosomal_S15 PF00312.22 OAJ14913.1 - 1.4e-23 82.9 0.1 1.4e-23 82.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 EVE PF01878.18 OAJ14940.1 - 5.1e-23 81.7 0.0 1.8e-22 79.9 0.0 1.9 1 1 0 1 1 1 1 EVE domain MCM_lid PF17855.1 OAJ14941.1 - 3.3e-08 33.8 0.7 1.5e-07 31.8 0.5 2.1 1 1 1 2 2 2 1 MCM AAA-lid domain DUF2457 PF10446.9 OAJ14941.1 - 0.18 10.9 10.9 0.046 12.9 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DMP1 PF07263.11 OAJ14941.1 - 0.37 9.6 7.5 0.54 9.1 7.5 1.2 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) NOA36 PF06524.12 OAJ14941.1 - 2.6 7.3 3.7 4.5 6.5 3.7 1.3 1 0 0 1 1 1 0 NOA36 protein Thr_dehydrat_C PF00585.18 OAJ14942.1 - 3.4e-16 58.8 0.0 6.3e-13 48.3 0.0 3.1 2 1 1 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase Hid1 PF12722.7 OAJ14942.1 - 3.2e-07 28.9 0.0 4.8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SEN1_N PF12726.7 OAJ14968.1 - 4.4e-79 266.6 3.6 1.5e-78 264.9 3.6 1.9 1 1 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 OAJ14968.1 - 5.3e-69 232.9 3.7 5.3e-69 232.9 3.7 2.5 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 OAJ14968.1 - 1.1e-59 201.4 0.0 1.1e-58 198.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ14968.1 - 1.5e-10 41.6 4.9 6.9e-10 39.4 2.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ14968.1 - 1.7e-09 37.7 0.5 7.3e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAJ14968.1 - 2.6e-05 24.1 0.0 1.4 8.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAJ14968.1 - 5.1e-05 22.9 1.3 5.1e-05 22.9 1.3 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 OAJ14968.1 - 0.0066 16.5 0.8 0.051 13.6 0.8 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HAUS6_N PF14661.6 OAJ14968.1 - 0.074 12.6 7.2 0.27 10.8 7.2 1.9 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_6 PF12774.7 OAJ14968.1 - 0.16 10.9 0.4 0.81 8.6 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 OAJ14968.1 - 0.6 10.5 4.0 0.75 10.2 1.7 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med9 PF07544.13 OAJ14968.1 - 0.74 9.9 7.1 2.9 8.0 7.1 2.0 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPR_14 PF13428.6 OAJ14994.1 - 8.2e-06 26.2 42.1 4 8.5 0.0 13.3 11 4 2 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 OAJ14994.1 - 5.2e-05 23.4 3.0 0.12 12.4 0.1 4.6 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_17 PF13431.6 OAJ14994.1 - 0.0067 16.7 9.9 17 6.0 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAJ14994.1 - 0.13 12.2 7.5 0.22 11.5 0.2 5.0 8 0 0 8 8 8 0 Mad3/BUB1 homology region 1 HAT PF02184.16 OAJ14994.1 - 0.5 10.4 8.1 2.9 7.9 0.1 5.7 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 OAJ14994.1 - 0.94 9.8 19.5 5.8 7.3 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ14994.1 - 5.6 7.8 9.7 2e+02 2.9 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat FAM176 PF14851.6 OAJ14994.1 - 6.9 6.3 17.2 3.4 7.3 2.1 4.3 4 0 0 4 4 4 0 FAM176 family DUF3246 PF11596.8 OAJ14994.1 - 9.7 5.5 7.7 7.1 6.0 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Methyltransf_23 PF13489.6 OAJ14995.1 - 1.3e-20 73.9 0.0 3e-20 72.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ14995.1 - 1.4e-16 60.9 0.8 1.2e-15 57.9 0.1 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ14995.1 - 5.8e-14 52.6 0.2 1.4e-11 45.0 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ14995.1 - 4.5e-13 49.3 0.0 2.9e-05 23.9 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ14995.1 - 4.7e-13 49.7 0.1 3.1e-12 47.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ14995.1 - 9.7e-07 28.3 0.0 0.013 14.8 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ14995.1 - 8.4e-06 24.9 0.0 0.0054 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1698) PrmA PF06325.13 OAJ14995.1 - 0.00021 20.8 0.0 0.00043 19.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 OAJ14995.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 OAJ14995.1 - 0.0065 16.1 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 2 Nodulation protein S (NodS) DREV PF05219.12 OAJ14995.1 - 0.023 13.8 0.0 0.056 12.5 0.0 1.6 1 1 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 OAJ14995.1 - 0.044 13.3 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ14995.1 - 0.053 12.9 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.11 OAJ14995.1 - 0.098 12.3 0.0 0.34 10.5 0.0 1.7 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 OAJ14995.1 - 0.11 12.1 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Miga PF10265.9 OAJ14995.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitoguardin DPBB_1 PF03330.18 OAJ15018.1 - 0.00026 21.2 0.0 0.00048 20.4 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ15018.1 - 0.0051 16.6 0.2 0.0084 16.0 0.2 1.4 1 1 0 1 1 1 1 Barwin family Cyclin_N PF00134.23 OAJ15019.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAJ15019.1 - 1.4e-08 35.1 0.1 4.3e-06 27.0 0.1 2.7 3 0 0 3 3 3 2 Cyclin C-terminal domain TFIIB PF00382.19 OAJ15019.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF4592 PF15262.6 OAJ15019.1 - 2.9 8.6 6.9 0.42 11.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) Speriolin_C PF15059.6 OAJ15021.1 - 0.16 12.1 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 Speriolin C-terminus HsbA PF12296.8 OAJ15050.1 - 3.3e-17 63.0 7.1 3.3e-17 63.0 7.1 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NMO PF03060.15 OAJ15070.1 - 6.1e-45 154.0 0.9 8e-44 150.4 0.9 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 OAJ15070.1 - 5.3e-09 35.5 0.5 0.0016 17.5 0.3 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 OAJ15070.1 - 0.00024 20.2 0.2 0.00038 19.6 0.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAJ15070.1 - 0.047 12.8 1.2 0.17 11.0 1.2 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 OAJ15070.1 - 0.047 13.1 0.1 0.099 12.1 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Retrotran_gag_2 PF14223.6 OAJ15071.1 - 4.6e-11 42.5 0.2 8.5e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ15071.1 - 1.6e-05 24.4 0.1 3.1e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 OAJ15071.1 - 0.00077 19.4 4.5 0.002 18.1 4.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ15071.1 - 0.031 14.1 2.1 0.081 12.8 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_3 PF14244.6 OAJ15071.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type eIF3g PF12353.8 OAJ15071.1 - 2.1 8.7 5.5 2.6 8.5 1.5 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G NifU_N PF01592.16 OAJ15072.1 - 1e-54 184.1 0.1 2.1e-54 183.1 0.1 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain RVT_1 PF00078.27 OAJ15097.1 - 7.5e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) INCENP_ARK-bind PF03941.15 OAJ15123.1 - 6.5e-11 42.0 0.3 1.6e-10 40.7 0.3 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DNA_primase_S PF01896.19 OAJ15124.1 - 9.8e-54 182.1 0.0 2.2e-53 180.9 0.0 1.6 1 1 0 1 1 1 1 DNA primase small subunit Seipin PF06775.14 OAJ15152.1 - 5.4e-41 140.9 0.0 2.7e-40 138.6 0.0 2.0 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) tRNA-synt_His PF13393.6 OAJ15153.1 - 7.6e-36 123.9 1.2 2.8e-31 109.0 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 OAJ15153.1 - 4e-08 33.3 0.0 8.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 OAJ15153.1 - 5.8e-06 26.4 2.0 5.8e-06 26.4 2.0 2.6 2 0 0 2 2 2 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 OAJ15153.1 - 0.00064 19.3 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 OAJ15153.1 - 0.082 12.0 0.8 0.81 8.7 0.4 2.3 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) RNA_pol_A_bac PF01000.26 OAJ15180.1 - 3.7e-27 94.9 0.0 5.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ15180.1 - 6.8e-19 67.1 0.0 9.2e-19 66.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 OAJ15181.1 - 8.7e-62 208.9 0.0 2.5e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15181.1 - 5.7e-34 117.6 0.0 6.2e-27 94.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ15181.1 - 1.8e-05 24.2 0.0 0.0023 17.3 0.0 3.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 OAJ15181.1 - 0.00097 19.1 0.0 0.0082 16.1 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ15181.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Palm_thioest PF02089.15 OAJ15182.1 - 5.7e-76 255.6 0.0 7.1e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAJ15182.1 - 0.049 13.3 0.1 0.14 11.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold COQ7 PF03232.13 OAJ15206.1 - 3.1e-62 209.4 0.1 5.9e-62 208.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 OAJ15206.1 - 0.054 13.4 0.2 0.8 9.6 0.0 2.4 2 0 0 2 2 2 0 Ferritin-like domain SYF2 PF08231.12 OAJ15207.1 - 2.4e-46 158.0 6.8 2.4e-46 158.0 6.8 2.0 2 0 0 2 2 2 1 SYF2 splicing factor WD40 PF00400.32 OAJ15207.1 - 0.074 13.9 0.4 2.1 9.3 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat BBE PF08031.12 OAJ15235.1 - 0.036 14.2 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Berberine and berberine like Cation_efflux PF01545.21 OAJ15236.1 - 4.3e-47 160.4 14.0 4.3e-47 160.4 14.0 2.4 3 1 0 3 3 3 1 Cation efflux family DUF1713 PF08213.11 OAJ15237.1 - 2.7e-10 40.0 25.0 4.4e-10 39.3 25.0 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) CDK2AP PF09806.9 OAJ15237.1 - 0.0064 16.6 3.4 0.009 16.1 3.4 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Protamine_P2 PF00841.19 OAJ15237.1 - 0.081 13.4 9.9 0.15 12.5 9.9 1.5 1 0 0 1 1 1 0 Sperm histone P2 Pex26 PF07163.12 OAJ15237.1 - 1.2 8.3 10.3 0.16 11.2 5.2 1.8 2 0 0 2 2 2 0 Pex26 protein Pkinase PF00069.25 OAJ15257.1 - 5.2e-49 167.0 0.0 7.2e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ15257.1 - 1e-29 103.6 0.0 2e-29 102.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase GAS PF13851.6 OAJ15257.1 - 0.046 13.1 1.7 0.073 12.4 1.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Kdo PF06293.14 OAJ15257.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CK2S PF15011.6 OAJ15257.1 - 0.12 12.3 2.1 0.22 11.4 2.1 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate UPF0242 PF06785.11 OAJ15257.1 - 0.17 12.0 0.3 0.28 11.3 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Allexi_40kDa PF05549.11 OAJ15257.1 - 0.2 11.2 1.2 0.68 9.4 0.5 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein RTC4 PF14474.6 OAJ15257.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 RTC4-like domain HALZ PF02183.18 OAJ15257.1 - 0.23 11.7 1.5 11 6.4 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 OAJ15257.1 - 0.24 10.7 1.5 0.37 10.1 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 OAJ15257.1 - 0.4 9.9 4.2 0.7 9.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 OAJ15257.1 - 0.6 10.3 5.0 1.1 9.5 5.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4140 PF13600.6 OAJ15257.1 - 1.4 9.4 9.8 12 6.4 2.9 3.7 3 2 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 OAJ15257.1 - 2 8.8 4.1 54 4.2 0.1 3.1 2 1 1 3 3 3 0 Csm1 N-terminal domain DivIC PF04977.15 OAJ15257.1 - 5.3 6.9 7.3 4.1 7.2 0.4 2.7 2 1 1 3 3 3 0 Septum formation initiator Dimer_Tnp_hAT PF05699.14 OAJ15258.1 - 9.7e-17 60.5 0.1 2.2e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DBD_Tnp_Hermes PF10683.9 OAJ15258.1 - 0.0026 17.4 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Hermes transposase DNA-binding domain DHHA1 PF02272.19 OAJ15286.1 - 0.38 11.2 6.3 1.9 8.9 6.3 1.9 1 1 0 1 1 1 0 DHHA1 domain PI-PLC-X PF00388.19 OAJ15310.1 - 4.5e-50 169.0 0.0 7.8e-50 168.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ15310.1 - 4.2e-38 130.2 0.0 1e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain ZFYVE21_C PF16696.5 OAJ15310.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc finger FYVE domain-containing protein 21 C-terminus GDPD PF03009.17 OAJ15310.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PH_12 PF16457.5 OAJ15310.1 - 0.25 11.9 0.1 0.25 11.9 0.1 3.8 3 2 1 4 4 4 0 Pleckstrin homology domain S4 PF01479.25 OAJ15329.1 - 1.1e-12 47.5 0.0 1.9e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 OAJ15329.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 S4 domain Plasmodium_Vir PF05795.11 OAJ15329.1 - 1.1 8.6 4.5 0.67 9.3 2.6 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein GREB1 PF15782.5 OAJ15329.1 - 1.8 5.6 3.0 2.2 5.3 3.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spore_coat_CotO PF14153.6 OAJ15329.1 - 7.8 6.4 10.5 12 5.7 10.5 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ras PF00071.22 OAJ15330.1 - 1.2e-44 151.8 0.0 5.4e-42 143.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 OAJ15330.1 - 9.6e-31 106.5 0.0 1.7e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ15330.1 - 1.7e-11 43.9 0.0 2.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ15330.1 - 0.00096 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ15330.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ15330.1 - 0.085 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 OAJ15330.1 - 0.16 11.9 0.0 0.7 9.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase DUF2781 PF10914.8 OAJ15331.1 - 0.015 15.7 4.6 0.015 15.7 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2781) RVT_1 PF00078.27 OAJ15350.1 - 3.3e-18 66.0 0.0 6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 OAJ15378.1 - 1.6e-11 44.6 14.4 5.1e-06 27.1 1.2 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15378.1 - 4e-11 43.1 0.0 0.0088 16.3 0.0 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 OAJ15378.1 - 1e-05 25.3 0.1 0.023 14.3 0.0 2.8 3 0 0 3 3 3 2 PQQ-like domain eIF2A PF08662.11 OAJ15378.1 - 1e-05 25.5 0.0 0.043 13.7 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 OAJ15378.1 - 0.045 14.3 0.0 0.78 10.3 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain Mito_fiss_reg PF05308.11 OAJ15378.1 - 0.61 10.1 4.2 0.65 10.0 2.2 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Aft1_HRA PF11786.8 OAJ15379.1 - 1.3e-21 76.7 21.4 1.3e-21 76.7 21.4 4.1 4 1 0 4 4 4 1 Aft1 HRA domain bZIP_1 PF00170.21 OAJ15379.1 - 4.7e-11 42.6 3.4 8.5e-11 41.8 3.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ15379.1 - 2.3e-06 27.6 5.5 5.1e-06 26.5 5.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Nop53 PF07767.11 OAJ15379.1 - 0.0015 18.0 2.4 0.0041 16.6 2.4 1.7 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 OAJ15379.1 - 0.021 13.1 2.5 0.047 12.0 2.5 1.5 1 0 0 1 1 1 0 CDC45-like protein Nnf1 PF03980.14 OAJ15379.1 - 4.7 7.6 6.0 1.2 9.5 2.1 2.1 2 0 0 2 2 2 0 Nnf1 TFB6 PF17110.5 OAJ15380.1 - 0.00022 21.0 1.7 2.2 8.0 0.0 3.9 3 1 0 3 3 3 2 Subunit 11 of the general transcription factor TFIIH TMEM171 PF15471.6 OAJ15380.1 - 0.59 9.1 1.4 0.99 8.3 1.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Endomucin PF07010.12 OAJ15407.1 - 0.57 10.1 13.5 1.3 9.0 13.5 1.5 1 0 0 1 1 1 0 Endomucin LIM PF00412.22 OAJ15408.1 - 3.1e-14 53.0 14.1 0.0002 21.5 0.0 5.5 6 0 0 6 6 6 4 LIM domain TPR_10 PF13374.6 OAJ15410.1 - 1e-34 117.4 33.2 8.8e-06 25.4 0.4 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15410.1 - 2.9e-26 91.6 43.5 4.7e-07 30.0 3.2 8.8 6 3 1 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ15410.1 - 2.5e-13 49.0 28.1 0.11 12.7 0.3 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ15410.1 - 1.2e-07 31.2 15.7 0.32 10.9 0.1 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat Vps4_C PF09336.10 OAJ15410.1 - 3.2e-06 27.0 0.1 2.4 8.2 0.0 5.6 6 0 0 6 6 6 2 Vps4 C terminal oligomerisation domain TPR_8 PF13181.6 OAJ15410.1 - 4.7e-06 26.4 25.0 5.3 7.5 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ15410.1 - 1.2e-05 25.4 17.7 0.1 12.6 3.8 4.6 2 2 1 4 4 4 4 Domain of Unknown Function (DUF3856) Pkinase_fungal PF17667.1 OAJ15410.1 - 0.014 14.2 4.7 20 3.8 1.7 4.2 3 1 1 4 4 4 0 Fungal protein kinase TPR_14 PF13428.6 OAJ15410.1 - 0.067 14.1 32.7 5.5 8.1 0.1 8.3 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ15410.1 - 0.2 11.8 25.6 18 5.7 0.2 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ15410.1 - 0.43 10.7 22.0 5.5 7.1 0.0 7.3 3 1 3 8 8 8 0 Anaphase-promoting complex subunit 5 SPOR PF05036.13 OAJ15410.1 - 0.99 9.8 4.0 16 6.0 0.5 3.5 2 1 1 3 3 3 0 Sporulation related domain TPR_16 PF13432.6 OAJ15410.1 - 2.5 8.8 28.6 3.4 8.4 0.3 7.1 8 1 1 9 9 8 0 Tetratricopeptide repeat Tcp11 PF05794.13 OAJ15436.1 - 4.5e-91 306.2 0.0 6.6e-90 302.3 0.0 2.4 1 1 0 1 1 1 1 T-complex protein 11 Motile_Sperm PF00635.26 OAJ15437.1 - 2.6e-20 72.3 0.0 5.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Integrase_H2C2 PF17921.1 OAJ15461.1 - 1e-15 57.5 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ15461.1 - 2.7e-13 50.2 0.0 7.2e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH PF17917.1 OAJ15461.1 - 1.9e-12 47.4 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ15461.1 - 1.2e-06 28.4 0.0 2.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 OAJ15461.1 - 0.081 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 H2C2 zinc finger RVT_1 PF00078.27 OAJ15462.1 - 9.1e-23 80.9 0.0 1.4e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ15462.1 - 2.7e-13 49.8 0.0 6.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ15462.1 - 5.6e-06 26.9 0.1 1.9e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease Integrase_H2C2 PF17921.1 OAJ15462.1 - 0.00017 21.7 0.0 0.0004 20.4 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ15462.1 - 0.0021 18.6 0.0 0.0059 17.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 OAJ15462.1 - 0.19 12.0 0.0 0.65 10.3 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ15463.1 - 1.3e-12 47.9 0.0 2.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ15463.1 - 2e-06 27.8 0.0 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ15463.1 - 0.00094 19.4 0.0 0.0023 18.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain MULE PF10551.9 OAJ15486.1 - 3.1e-18 66.0 0.8 8.9e-18 64.5 0.1 2.1 3 0 0 3 3 3 1 MULE transposase domain Transposase_mut PF00872.18 OAJ15486.1 - 6.5e-08 31.8 1.1 3.7e-07 29.3 0.1 2.1 2 0 0 2 2 2 1 Transposase, Mutator family DDE_Tnp_ISL3 PF01610.17 OAJ15486.1 - 5.3e-05 23.1 0.3 0.00015 21.6 0.2 1.7 1 1 1 2 2 2 1 Transposase DDE_Tnp_IS240 PF13610.6 OAJ15486.1 - 0.0017 18.6 0.0 0.0042 17.3 0.0 1.6 1 0 0 1 1 1 1 DDE domain rve PF00665.26 OAJ15486.1 - 0.0055 16.9 0.3 0.015 15.5 0.3 1.8 1 0 0 1 1 1 1 Integrase core domain DUF5575 PF17738.1 OAJ15486.1 - 0.13 11.3 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Retrotrans_gag PF03732.17 OAJ15512.1 - 4.8e-17 62.0 1.0 8.7e-17 61.2 1.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ15512.1 - 0.0015 18.5 0.5 0.0025 17.8 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF4939 PF16297.5 OAJ15512.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Hydrolase_2 PF07486.12 OAJ15512.1 - 0.01 16.7 0.1 0.031 15.1 0.0 1.8 1 1 0 1 1 1 0 Cell Wall Hydrolase zf-CCHC_3 PF13917.6 OAJ15512.1 - 0.019 14.9 0.5 0.04 13.9 0.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF2300 PF10062.9 OAJ15512.1 - 0.05 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) CPSase_L_D2 PF02786.17 OAJ15513.1 - 2.7e-50 170.8 0.0 4.3e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Carboxyl_trans PF01039.22 OAJ15513.1 - 4.1e-45 154.3 0.1 1.7e-40 139.1 0.0 2.1 2 0 0 2 2 2 2 Carboxyl transferase domain Biotin_carb_N PF00289.22 OAJ15513.1 - 3.3e-24 85.6 0.0 2.6e-23 82.7 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ15513.1 - 2.6e-20 72.5 0.0 5.6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ15513.1 - 8.2e-17 60.8 0.1 1.7e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ15513.1 - 1.4e-07 31.2 0.3 0.0049 16.7 0.7 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_ST PF14397.6 OAJ15513.1 - 0.0006 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 OAJ15513.1 - 0.0014 19.3 0.4 1.3 9.7 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein RnfC_N PF13375.6 OAJ15513.1 - 0.0037 17.2 0.1 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain RT_RNaseH PF17917.1 OAJ15514.1 - 2.8e-34 117.6 0.0 5.4e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ15514.1 - 7e-33 112.7 0.0 1.6e-32 111.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ15514.1 - 8.1e-31 107.2 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 OAJ15514.1 - 2.5e-06 27.3 0.0 4.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 OAJ15514.1 - 0.00018 22.1 0.0 0.00034 21.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ15514.1 - 0.00092 19.7 0.0 0.0021 18.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pol_alpha_B_N PF08418.10 OAJ15514.1 - 2.9 7.8 8.2 4.8 7.1 8.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RRN3 PF05327.11 OAJ15537.1 - 0.55 8.7 4.9 1 7.9 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 OAJ15537.1 - 1.6 6.8 13.9 3.4 5.8 13.9 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ15537.1 - 3.2 5.9 10.6 5.7 5.1 10.6 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ15537.1 - 3.8 7.2 6.3 0.7 9.5 1.9 2.1 2 0 0 2 2 2 0 FAM176 family BTAD PF03704.17 OAJ15538.1 - 0.0019 18.6 1.9 2.4 8.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_2 PF07719.17 OAJ15538.1 - 0.016 15.2 2.1 1.4 9.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ15538.1 - 0.086 13.1 1.1 17 5.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ15538.1 - 0.27 11.6 5.2 19 5.7 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat p450 PF00067.22 OAJ15560.1 - 2.3e-10 39.8 0.0 3.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AAA PF00004.29 OAJ15562.1 - 2.8e-14 53.7 0.0 6e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ15562.1 - 1.4e-11 44.4 0.0 4.8e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 OAJ15562.1 - 1.1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 OAJ15562.1 - 1.4e-05 25.4 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 OAJ15562.1 - 8.3e-05 22.6 0.0 0.00026 21.0 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 OAJ15562.1 - 0.00041 20.6 0.2 0.027 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ15562.1 - 0.00046 20.5 0.0 0.0016 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ15562.1 - 0.00073 20.0 0.1 0.012 16.0 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 OAJ15562.1 - 0.00076 19.3 0.0 0.0024 17.7 0.0 1.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ15562.1 - 0.00078 19.2 0.0 0.0035 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 OAJ15562.1 - 0.00097 19.4 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DUF2075 PF09848.9 OAJ15562.1 - 0.0018 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 OAJ15562.1 - 0.002 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ15562.1 - 0.0024 17.6 0.0 0.0068 16.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 OAJ15562.1 - 0.0029 17.4 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 OAJ15562.1 - 0.014 14.7 0.0 0.097 12.0 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 OAJ15562.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAJ15562.1 - 0.093 12.7 0.3 1 9.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 OAJ15562.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 OAJ15562.1 - 0.12 12.3 0.0 2 8.4 0.0 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.23 OAJ15562.1 - 0.15 11.1 0.1 1.2 8.2 0.1 2.2 1 1 0 1 1 1 0 MCM P-loop domain Unstab_antitox PF09720.10 OAJ15584.1 - 0.03 14.4 2.2 0.11 12.5 0.5 2.7 2 0 0 2 2 2 0 Putative addiction module component Ribonuc_2-5A PF06479.12 OAJ15584.1 - 0.3 11.3 3.2 5.1 7.3 3.7 2.5 2 1 0 2 2 2 0 Ribonuclease 2-5A DUF4218 PF13960.6 OAJ15585.1 - 0.007 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Ribosomal_L18 PF17135.4 OAJ15616.1 - 8.8e-90 299.1 2.0 1.1e-89 298.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 OAJ15616.1 - 0.00082 20.1 0.0 0.002 18.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A UAA PF08449.11 OAJ15617.1 - 9.2e-40 136.7 6.5 7.6e-39 133.7 6.5 2.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 OAJ15617.1 - 5.4e-06 26.6 3.2 5.4e-06 26.6 3.2 4.6 5 1 0 5 5 5 1 EamA-like transporter family Nuc_sug_transp PF04142.15 OAJ15617.1 - 0.0014 17.9 1.8 0.48 9.5 0.1 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 OAJ15617.1 - 0.0019 17.6 5.1 0.22 10.8 0.5 2.7 3 0 0 3 3 3 2 Triose-phosphate Transporter family CRT-like PF08627.10 OAJ15617.1 - 0.015 14.2 3.9 0.74 8.7 0.2 2.2 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 OAJ15617.1 - 0.028 14.4 1.6 3.9 7.5 0.3 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 CbiG_N PF11760.8 OAJ15617.1 - 0.099 12.7 0.2 0.099 12.7 0.2 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal RRM_1 PF00076.22 OAJ15618.1 - 5e-14 51.9 0.0 7e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.12 OAJ15619.1 - 1.3e-14 54.4 6.9 1.8e-14 53.9 6.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 OAJ15619.1 - 8.3e-09 35.5 0.5 8.3e-09 35.5 0.5 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction V_ATPase_I PF01496.19 OAJ15619.1 - 0.00038 18.5 0.0 0.00091 17.3 0.0 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Phage_holin_3_6 PF07332.11 OAJ15619.1 - 0.013 15.6 15.3 1.5 8.9 12.1 3.1 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III SPC25 PF06703.11 OAJ15619.1 - 0.063 13.1 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3357 PF11837.8 OAJ15619.1 - 0.83 10.1 4.9 1.5 9.3 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) SLATT_3 PF18184.1 OAJ15619.1 - 2 8.5 5.3 4.1 7.5 5.3 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 3 LptF_LptG PF03739.14 OAJ15619.1 - 4.7 5.9 12.1 0.096 11.5 5.2 1.7 1 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF2070 PF09843.9 OAJ15619.1 - 5 5.3 14.1 7.7 4.7 14.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GFA PF04828.14 OAJ15647.1 - 0.011 16.0 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF883 PF05957.13 OAJ15648.1 - 1.4 9.6 9.1 7.2 7.3 3.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3432 PF11914.8 OAJ15673.1 - 0.034 14.4 7.4 0.05 13.9 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) Glyco_transf_20 PF00982.21 OAJ15674.1 - 4.1e-142 474.2 0.0 5.8e-142 473.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ15674.1 - 4.2e-22 78.4 0.0 7.5e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Methyltransf_28 PF02636.17 OAJ15704.1 - 9.6e-36 123.7 0.0 1.7e-35 122.9 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rsm22 PF09243.10 OAJ15704.1 - 4.2e-26 91.8 9.3 1.3e-09 37.7 0.0 5.8 4 2 1 5 5 5 4 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 OAJ15704.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CNDH2_C PF16858.5 OAJ15704.1 - 1.3 8.8 5.6 11 5.7 0.7 2.5 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nucleo_P87 PF07267.11 OAJ15704.1 - 1.8 7.3 3.8 0.73 8.6 0.7 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 GPI-anchored PF10342.9 OAJ15705.1 - 8e-12 45.8 1.0 8e-12 45.8 1.0 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF1206 PF06724.11 OAJ15705.1 - 0.52 10.4 6.9 3.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Apt1 PF10351.9 OAJ15705.1 - 0.58 8.9 7.9 0.71 8.7 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MGC-24 PF05283.11 OAJ15705.1 - 1.8 9.0 11.6 4 7.9 11.6 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hamartin PF04388.12 OAJ15705.1 - 3.2 6.3 8.9 3.4 6.2 8.9 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 OAJ15705.1 - 4.8 4.2 5.1 5.7 3.9 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SPX PF03105.19 OAJ15705.1 - 8.6 6.2 11.2 11 5.8 11.2 1.1 1 0 0 1 1 1 0 SPX domain SSP160 PF06933.11 OAJ15705.1 - 9.3 4.3 29.0 19 3.3 29.0 1.5 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cyclin_N PF00134.23 OAJ15732.1 - 3.9e-41 139.8 0.3 9.4e-41 138.5 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ15732.1 - 5.7e-29 100.6 0.0 1.5e-28 99.3 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Gemini_AL3 PF01407.17 OAJ15732.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL3 protein Peptidase_M28 PF04389.17 OAJ15733.1 - 1.7e-26 93.2 0.0 3.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAJ15733.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DPM2 PF07297.12 OAJ15734.1 - 4e-28 97.5 0.2 4.6e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 OAJ15734.1 - 2.1e-05 24.4 0.1 2.5e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 OAJ15734.1 - 0.034 14.2 0.1 0.043 13.9 0.1 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4083 PF13314.6 OAJ15734.1 - 0.14 12.1 0.3 2 8.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DJ-1_PfpI PF01965.24 OAJ15735.1 - 7.6e-38 129.9 0.1 8.8e-38 129.7 0.1 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family MtmB PF05369.12 OAJ15735.1 - 0.016 14.1 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB DUF4965 PF16335.5 OAJ15761.1 - 1e-66 223.9 0.0 1.9e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 OAJ15761.1 - 2e-65 220.3 0.3 5.1e-65 219.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF5127 PF17168.4 OAJ15761.1 - 6.3e-48 163.5 4.8 1.3e-47 162.5 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ15761.1 - 0.002 17.7 2.6 1.1 8.9 0.2 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ15761.1 - 0.0091 15.5 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4677 PF15726.5 OAJ15762.1 - 3.3 7.8 6.0 0.45 10.7 0.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4677) Proteasome PF00227.26 OAJ15763.1 - 1.4e-48 164.9 0.2 2e-48 164.4 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF2188 PF09954.9 OAJ15763.1 - 0.0016 18.5 0.8 0.059 13.5 0.2 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2188) Ntox44 PF15607.6 OAJ15763.1 - 0.12 12.7 0.2 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial toxin 44 Phos_pyr_kin PF08543.12 OAJ15764.1 - 5.1e-09 35.9 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 OAJ15764.1 - 1.2e-05 24.8 0.0 4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DPPIV_N PF00930.21 OAJ15789.1 - 1.1e-73 248.1 0.0 1.5e-72 244.3 0.0 2.3 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 OAJ15789.1 - 3.7e-42 144.2 0.5 6.3e-42 143.5 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 OAJ15789.1 - 0.0012 18.5 0.8 0.0058 16.3 0.6 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAJ15789.1 - 0.028 13.1 0.0 0.073 11.7 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Actin PF00022.19 OAJ15816.1 - 4.2e-99 331.9 0.0 1.7e-98 330.0 0.0 1.9 1 1 0 1 1 1 1 Actin Sad1_UNC PF07738.13 OAJ15817.1 - 7.7e-12 45.4 0.0 6.3e-05 23.0 0.0 3.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal TFIIA PF03153.13 OAJ15817.1 - 0.0072 16.4 0.4 0.016 15.3 0.4 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RunxI PF08504.11 OAJ15817.1 - 0.27 11.9 3.4 1.2 9.9 3.4 2.1 1 0 0 1 1 1 0 Runx inhibition domain BOP1NT PF08145.12 OAJ15818.1 - 4e-106 354.7 1.9 6.3e-106 354.1 1.9 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 OAJ15818.1 - 1.9e-20 72.8 2.4 5e-06 27.1 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ15818.1 - 0.0018 18.6 0.0 2.2 8.6 0.0 4.1 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BUD22 PF09073.10 OAJ15818.1 - 0.23 10.8 19.8 0.38 10.0 19.8 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ15818.1 - 3.5 5.7 25.4 5 5.2 25.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ15818.1 - 9.7 5.5 25.4 17 4.7 25.4 1.3 1 0 0 1 1 1 0 SDA1 OTCace_N PF02729.21 OAJ15846.1 - 1.5e-46 158.1 0.1 2.5e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 OAJ15846.1 - 8.5e-46 155.9 0.0 1.2e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF5432 PF17497.2 OAJ15846.1 - 0.19 11.8 0.1 0.59 10.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5432) Pribosyltran_N PF13793.6 OAJ15848.1 - 6.7e-44 148.5 0.0 7e-43 145.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ15848.1 - 7.3e-35 120.7 2.8 1.8e-31 109.6 0.6 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ15848.1 - 2.6e-15 56.3 1.4 5.2e-14 52.1 0.9 2.8 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ15848.1 - 0.013 14.9 0.1 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 OAJ15848.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Sterol_MT_C PF08498.10 OAJ15848.1 - 0.16 12.3 1.3 5.6 7.4 0.1 2.5 1 1 1 2 2 2 0 Sterol methyltransferase C-terminal Rft-1 PF04506.13 OAJ15849.1 - 4.9e-109 365.4 0.0 5.6e-109 365.2 0.0 1.0 1 0 0 1 1 1 1 Rft protein RabGAP-TBC PF00566.18 OAJ15850.1 - 4.3e-36 124.6 0.1 5.8e-36 124.2 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Zn_clus PF00172.18 OAJ15877.1 - 0.00013 22.0 10.3 0.00023 21.2 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.18 OAJ15904.1 - 4.3e-56 189.7 1.4 7.8e-56 188.8 1.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ15904.1 - 1.3e-34 118.6 0.0 3.1e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 OAJ15904.1 - 0.0018 18.6 0.2 0.0056 16.9 0.2 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAJ15904.1 - 0.0023 17.9 0.2 0.0044 17.0 0.2 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF1188 PF06690.11 OAJ15904.1 - 0.0064 16.1 0.2 0.02 14.4 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1188) UDPG_MGDP_dh_N PF03721.14 OAJ15904.1 - 0.02 14.4 0.6 0.082 12.5 0.6 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 OAJ15904.1 - 0.04 14.0 1.1 0.58 10.2 0.2 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 OAJ15904.1 - 0.057 13.6 3.2 0.25 11.5 2.2 2.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 OAJ15904.1 - 0.12 12.5 1.9 0.54 10.4 0.9 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus His_Phos_1 PF00300.22 OAJ15905.1 - 6.5e-39 133.6 0.0 7.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Nup192 PF11894.8 OAJ15928.1 - 1.7e-223 744.9 4.4 2.1e-223 744.6 4.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 OAJ15928.1 - 0.12 10.3 0.1 0.31 8.9 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin subcomplex protein binding to Pom34 Myc_N PF01056.18 OAJ15951.1 - 0.0034 17.3 0.1 0.0036 17.2 0.1 1.0 1 0 0 1 1 1 1 Myc amino-terminal region TIMELESS_C PF05029.13 OAJ15951.1 - 0.011 15.0 0.4 0.011 14.9 0.4 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region Prok-TraM PF09228.10 OAJ15951.1 - 0.072 13.5 0.0 0.079 13.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Herpes_gE PF02480.16 OAJ15951.1 - 0.17 10.6 1.2 0.2 10.4 1.2 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E HATPase_c PF02518.26 OAJ15952.1 - 8.7e-29 100.3 0.1 3.4e-28 98.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ15952.1 - 6e-24 84.4 0.2 1.3e-23 83.3 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 OAJ15952.1 - 2.2e-23 82.6 2.3 2.8e-11 43.6 0.0 6.2 5 1 0 5 5 5 3 PAS fold HisKA PF00512.25 OAJ15952.1 - 1.6e-19 69.6 0.1 3.9e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 OAJ15952.1 - 4.8e-13 49.1 0.2 0.0072 16.3 0.0 5.7 6 1 0 6 6 6 3 PAS fold PAS_3 PF08447.12 OAJ15952.1 - 6.4e-13 48.8 1.1 1.1e-12 48.0 0.2 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 OAJ15952.1 - 2.9e-07 30.7 0.0 5.1e-05 23.5 0.0 3.6 4 1 0 4 4 4 1 PAS domain PAS_8 PF13188.7 OAJ15952.1 - 0.0016 18.4 0.0 27 4.9 0.0 4.3 4 0 0 4 4 4 0 PAS domain HATPase_c_3 PF13589.6 OAJ15952.1 - 0.0046 16.8 0.4 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mto2_bdg PF12808.7 OAJ15976.1 - 0.0042 17.4 0.1 0.0072 16.6 0.1 1.3 1 0 0 1 1 1 1 Micro-tubular organiser Mto1 C-term Mto2-binding region BRE1 PF08647.11 OAJ15976.1 - 0.027 14.6 0.9 0.035 14.2 0.9 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase IFT57 PF10498.9 OAJ15976.1 - 0.038 13.0 0.3 0.048 12.6 0.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.9 OAJ15976.1 - 0.057 13.5 0.3 0.084 12.9 0.3 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SNF5 PF04855.12 OAJ16007.1 - 3.1e-59 200.6 2.1 5.4e-59 199.9 2.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 OAJ16007.1 - 0.0038 16.8 1.3 0.014 15.0 1.3 2.1 1 0 0 1 1 1 1 GATA zinc finger FYDLN_acid PF09538.10 OAJ16007.1 - 0.079 13.7 0.0 0.079 13.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (FYDLN_acid) TolB_N PF04052.13 OAJ16007.1 - 0.15 12.3 0.3 0.94 9.7 0.0 2.2 2 0 0 2 2 2 0 TolB amino-terminal domain Inhibitor_I53 PF11714.8 OAJ16008.1 - 0.0023 18.1 0.9 0.0023 18.1 0.9 1.8 2 0 0 2 2 2 1 Thrombin inhibitor Madanin RRN3 PF05327.11 OAJ16008.1 - 3.7 6.0 6.8 5.9 5.3 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MULE PF10551.9 OAJ16034.1 - 0.0019 18.6 0.3 0.012 16.0 0.0 2.5 3 0 0 3 3 3 1 MULE transposase domain SWIM PF04434.17 OAJ16034.1 - 0.012 15.3 0.5 0.026 14.2 0.5 1.5 1 0 0 1 1 1 0 SWIM zinc finger Iso_dh PF00180.20 OAJ16056.1 - 3.4e-78 263.2 0.0 5e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TFIIA PF03153.13 OAJ16057.1 - 0.029 14.4 26.3 0.014 15.5 17.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TetR_C_14 PF17754.1 OAJ16057.1 - 0.067 13.1 0.3 17 5.4 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain TMEM51 PF15345.6 OAJ16057.1 - 0.92 9.3 9.8 1.5 8.6 9.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Spt20 PF12090.8 OAJ16057.1 - 2 7.9 28.3 0.57 9.7 17.3 2.3 2 0 0 2 2 2 0 Spt20 family Ribonuclease_T2 PF00445.18 OAJ16058.1 - 2.2e-34 119.3 0.1 2.8e-34 118.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family GFO_IDH_MocA PF01408.22 OAJ16059.1 - 3.4e-16 60.1 0.1 5e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pro_Al_protease PF02983.14 OAJ16059.1 - 0.098 12.7 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Alpha-lytic protease prodomain RhoGEF PF00621.20 OAJ16087.1 - 9.1e-13 48.8 0.0 3.8e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain RT_RNaseH_2 PF17919.1 OAJ16110.1 - 3e-23 81.8 0.0 2.9e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ16110.1 - 4.5e-23 81.9 0.0 7.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ16110.1 - 7.1e-17 61.6 0.0 2.9e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ16110.1 - 3.9e-15 55.7 0.0 9.1e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ16110.1 - 2.9e-11 43.6 0.0 7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Strep_pep PF14404.6 OAJ16110.1 - 0.061 13.6 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species CheC PF04509.12 OAJ16110.1 - 0.21 11.5 0.1 0.45 10.5 0.1 1.5 1 0 0 1 1 1 0 CheC-like family AAA PF00004.29 OAJ16111.1 - 9.2e-09 35.8 0.1 4.1e-08 33.7 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mito_carr PF00153.27 OAJ16111.1 - 1.5e-07 31.3 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein AAA_33 PF13671.6 OAJ16111.1 - 3.8e-06 27.1 0.0 7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ16111.1 - 4.9e-05 23.8 0.0 8.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 OAJ16111.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ16111.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ16111.1 - 0.0031 17.1 0.1 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ16111.1 - 0.0057 16.4 0.1 0.0082 15.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ16111.1 - 0.022 14.5 0.1 0.048 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 OAJ16111.1 - 0.037 14.3 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ16111.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAJ16111.1 - 0.21 11.9 0.1 0.41 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Orthopox_F8 PF05886.11 OAJ16144.1 - 0.0067 16.5 6.0 0.14 12.3 1.9 3.3 2 0 0 2 2 2 2 Orthopoxvirus F8 protein DUF3381 PF11861.8 OAJ16145.1 - 0.13 12.0 0.9 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) NAT PF04768.13 OAJ16146.1 - 6.8e-27 94.2 0.0 4.8e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase CdiA_C_tRNase PF18664.1 OAJ16146.1 - 0.029 14.6 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain DDE_1 PF03184.19 OAJ16174.1 - 2.9e-19 69.4 0.0 7.7e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ16174.1 - 3.3e-05 23.8 0.0 9.8e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 OAJ16174.1 - 0.00066 19.1 0.1 0.0017 17.8 0.1 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_psq PF05225.16 OAJ16174.1 - 0.026 14.3 0.0 0.073 12.8 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Asp-B-Hydro_N PF05279.11 OAJ16174.1 - 4.7 7.2 25.7 7.5 6.5 25.7 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_11 PF13086.6 OAJ16174.1 - 5.8 6.6 16.5 12 5.6 16.5 1.6 1 0 0 1 1 1 0 AAA domain PHD PF00628.29 OAJ16175.1 - 0.00063 19.6 7.8 0.00063 19.6 7.8 1.9 2 0 0 2 2 2 1 PHD-finger TPR_MLP1_2 PF07926.12 OAJ16175.1 - 0.075 13.1 1.9 0.12 12.4 1.1 1.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-HC5HC2H PF13771.6 OAJ16175.1 - 0.089 13.0 3.6 1.3 9.3 1.3 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 OAJ16175.1 - 0.45 10.7 6.0 4.2 7.6 1.9 2.4 1 1 1 2 2 2 0 PHD-zinc-finger like domain rve PF00665.26 OAJ16176.1 - 1.8e-07 31.3 0.0 7.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HTH_23 PF13384.6 OAJ16176.1 - 0.093 12.6 0.5 0.43 10.5 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain WD40 PF00400.32 OAJ16201.1 - 6.5e-10 39.4 4.0 0.016 16.0 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ16201.1 - 0.00028 21.1 0.0 1.6 9.0 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ16201.1 - 0.014 14.4 0.0 0.23 10.4 0.0 2.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 OAJ16202.1 - 6.3e-64 216.4 0.0 1.3e-63 215.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 OAJ16203.1 - 3.2e-63 214.1 0.0 7.6e-63 212.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 CENP-B_dimeris PF09026.10 OAJ16227.1 - 0.033 14.6 34.1 1.7 9.1 7.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OAJ16227.1 - 0.13 12.0 0.1 0.13 12.0 0.1 3.3 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Kinesin PF00225.23 OAJ16228.1 - 2.4e-71 240.4 0.4 3.3e-43 147.9 0.0 2.9 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 OAJ16228.1 - 6e-10 39.2 0.0 8.5e-06 25.8 0.0 3.7 4 0 0 4 4 4 2 Microtubule binding DUF1749 PF08538.10 OAJ16261.1 - 1.1e-06 27.9 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 OAJ16261.1 - 0.00019 20.8 0.1 0.022 14.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAJ16261.1 - 0.031 13.7 0.0 0.058 12.9 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.11 OAJ16261.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) NAD_binding_10 PF13460.6 OAJ16262.1 - 0.0092 15.9 0.3 0.07 13.0 0.3 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Histone PF00125.24 OAJ16325.1 - 2.3e-45 154.1 2.7 2.6e-45 154.0 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ16325.1 - 3.1e-05 24.1 0.9 4.9e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ16325.1 - 3.5e-05 24.1 0.0 5.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ16325.1 - 0.0004 20.6 0.1 0.00077 19.7 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ16325.1 - 0.0043 17.1 0.1 0.0071 16.4 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PAF PF15715.5 OAJ16325.1 - 0.02 15.5 1.0 0.027 15.1 1.0 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain HisKA PF00512.25 OAJ16325.1 - 0.052 13.6 0.1 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Transposase_21 PF02992.14 OAJ16328.1 - 8.4e-15 54.6 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ16328.1 - 0.039 13.6 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Zn_clus PF00172.18 OAJ16358.1 - 6.1e-07 29.5 11.1 1.2e-06 28.6 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomerase_RBD PF12009.8 OAJ16359.1 - 3.4e-40 137.3 0.0 8.6e-40 135.9 0.0 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 OAJ16359.1 - 9.7e-09 35.1 0.0 2.8e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Peroxin-3 PF04882.12 OAJ16390.1 - 2.5e-109 366.4 19.5 6.2e-106 355.2 19.5 2.2 1 1 0 1 1 1 1 Peroxin-3 EXS PF03124.14 OAJ16415.1 - 3.2e-85 286.4 30.7 4.4e-85 285.9 30.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 OAJ16415.1 - 2.7e-30 106.6 8.0 2.7e-30 106.6 8.0 1.8 2 0 0 2 2 2 1 SPX domain MMR_HSR1 PF01926.23 OAJ16416.1 - 1e-15 57.8 0.1 1.3e-13 51.1 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ16416.1 - 2.3e-07 30.5 0.1 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ16416.1 - 0.00013 21.9 0.4 0.1 12.5 0.1 2.4 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ16416.1 - 0.00024 20.7 0.0 0.011 15.3 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ16416.1 - 0.00035 20.7 1.3 0.21 11.6 0.1 3.3 2 1 1 3 3 3 1 Dynamin family Herpes_UL56 PF04534.12 OAJ16416.1 - 0.056 12.9 0.1 0.056 12.9 0.1 2.4 1 1 1 2 2 2 0 Herpesvirus UL56 protein MULE PF10551.9 OAJ16447.1 - 5.5e-20 71.6 0.2 1.2e-19 70.5 0.2 1.6 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ16447.1 - 0.00042 21.0 2.4 0.0009 19.9 2.4 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.18 OAJ16447.1 - 0.00074 18.5 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DDE_Tnp_IS240 PF13610.6 OAJ16447.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 DDE domain AFT PF08731.11 OAJ16447.1 - 0.14 12.6 1.9 0.21 12.0 0.7 1.9 2 1 0 2 2 2 0 Transcription factor AFT DUF1722 PF08349.11 OAJ16447.1 - 0.15 12.3 0.4 0.29 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) gp12-short_mid PF09089.10 OAJ16447.1 - 0.21 11.8 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain SWIM PF04434.17 OAJ16448.1 - 0.0031 17.2 0.8 0.0055 16.4 0.8 1.4 1 0 0 1 1 1 1 SWIM zinc finger RGS_DHEX PF18148.1 OAJ16448.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain OrfB_IS605 PF01385.19 OAJ16448.1 - 0.03 14.5 2.4 0.041 14.1 1.3 1.8 2 0 0 2 2 2 0 Probable transposase PIF1 PF05970.14 OAJ16479.1 - 2.4e-105 352.7 0.0 3.2e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ16479.1 - 6.7e-56 189.5 0.1 1.6e-55 188.3 0.1 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ16479.1 - 2.8e-08 33.7 0.0 4.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ16479.1 - 0.00011 20.3 0.0 0.00033 18.7 0.0 1.6 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 OAJ16479.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 OAJ16479.1 - 0.015 15.6 0.0 0.04 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 OAJ16479.1 - 0.016 14.5 0.0 0.07 12.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin UvrD_C_2 PF13538.6 OAJ16479.1 - 0.018 14.9 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain TrwB_AAD_bind PF10412.9 OAJ16479.1 - 0.024 13.6 0.0 0.077 11.9 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 OAJ16479.1 - 0.085 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2791 PF10923.8 OAJ16479.1 - 0.15 10.8 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CorA PF01544.18 OAJ16508.1 - 1.1e-08 34.8 4.9 2.5e-08 33.6 4.9 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein PhetRS_B1 PF18262.1 OAJ16508.1 - 0.4 10.9 1.3 0.99 9.7 0.2 2.1 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain DUF4603 PF15376.6 OAJ16508.1 - 4.7 4.5 10.3 6.9 3.9 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Sporozoite_P67 PF05642.11 OAJ16508.1 - 5.8 4.9 7.9 8.7 4.3 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen dCache_1 PF02743.18 OAJ16508.1 - 6.5 6.5 7.3 81 2.9 7.3 2.2 1 1 0 1 1 1 0 Cache domain GDP_Man_Dehyd PF16363.5 OAJ16510.1 - 7e-43 147.3 0.0 8.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ16510.1 - 2.1e-41 142.0 0.0 2.5e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ16510.1 - 2.6e-12 46.3 0.0 9.4e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ16510.1 - 3.8e-07 29.5 0.0 5.8e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAJ16510.1 - 1.5e-06 27.6 0.0 3.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAJ16510.1 - 1.4e-05 24.5 0.0 2.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 OAJ16510.1 - 9e-05 22.5 0.1 0.00027 20.9 0.1 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 OAJ16510.1 - 0.00083 18.9 0.0 0.0019 17.7 0.0 1.7 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 OAJ16510.1 - 0.0015 18.4 0.0 0.0086 16.0 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Ribonuc_L-PSP PF01042.21 OAJ16510.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP ATP-synt_C PF00137.21 OAJ16567.1 - 1.1e-33 115.4 36.7 8.9e-22 77.2 15.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 OAJ16567.1 - 6.4 6.6 7.1 5.5 6.8 5.7 1.6 1 1 0 1 1 1 0 Inclusion membrane protein D Fe-S_biosyn PF01521.20 OAJ16568.1 - 0.00018 21.7 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Cation_efflux PF01545.21 OAJ16569.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Cation efflux family Transposase_20 PF02371.16 OAJ16569.1 - 0.003 17.8 0.8 0.0079 16.5 0.8 1.7 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family DNA_pol_delta_4 PF04081.13 OAJ16570.1 - 9.7e-25 87.4 0.0 1.4e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Cutinase PF01083.22 OAJ16594.1 - 1.9e-20 73.6 0.0 2.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ16594.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Pkinase PF00069.25 OAJ16596.1 - 8.6e-59 199.0 0.0 3.4e-58 197.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF3543 PF12063.8 OAJ16596.1 - 1e-39 136.4 0.1 3.6e-35 121.6 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.17 OAJ16596.1 - 1.7e-38 132.4 0.0 4.2e-38 131.1 0.0 1.5 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ16596.1 - 0.0047 16.3 0.0 2.8 7.2 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAJ16596.1 - 0.0077 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ16596.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arrestin_C PF02752.22 OAJ16625.1 - 2.5e-07 31.2 0.0 1.9e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ16625.1 - 0.00062 19.8 0.0 1.5 8.9 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Serglycin PF04360.12 OAJ16625.1 - 0.098 12.6 9.2 1.9 8.4 1.6 3.3 2 0 0 2 2 2 0 Serglycin MG2 PF01835.19 OAJ16625.1 - 0.12 12.9 0.1 0.42 11.1 0.0 2.0 2 0 0 2 2 2 0 MG2 domain Peptidase_S10 PF00450.22 OAJ16626.1 - 6.9e-90 302.4 0.0 9e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Vta1_C PF18097.1 OAJ16626.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Vta1 C-terminal domain FF PF01846.19 OAJ16657.1 - 6.9e-16 58.2 15.7 2.2e-06 27.7 0.4 5.1 4 1 0 4 4 4 4 FF domain RhoGAP-FF1 PF16512.5 OAJ16657.1 - 0.0043 17.7 0.9 0.25 12.1 0.0 3.6 3 1 0 3 3 3 1 p190-A and -B Rho GAPs FF domain CDC45 PF02724.14 OAJ16657.1 - 1.3 7.3 11.6 1.3 7.2 10.5 1.6 1 1 0 1 1 1 0 CDC45-like protein Oxysterol_BP PF01237.18 OAJ16658.1 - 1.7e-113 379.2 0.0 5.8e-113 377.5 0.0 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 OAJ16658.1 - 4.5e-16 58.9 0.0 8.8e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ16658.1 - 3e-06 27.7 0.0 6.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PH domain MOZ_SAS PF01853.18 OAJ16659.1 - 3.8e-80 267.8 0.0 5.4e-80 267.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ16659.1 - 2.4e-23 81.5 1.7 4.1e-23 80.7 1.7 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 OAJ16659.1 - 7.2e-19 67.4 0.2 2.6e-18 65.6 0.2 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 OAJ16659.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ16659.1 - 0.012 15.9 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAM176 PF14851.6 OAJ16659.1 - 0.46 10.1 17.3 0.19 11.4 8.3 3.3 3 0 0 3 3 3 0 FAM176 family Myc_N PF01056.18 OAJ16659.1 - 0.62 9.9 17.8 0.058 13.3 10.5 2.4 2 0 0 2 2 2 0 Myc amino-terminal region MASE2 PF05230.11 OAJ16751.1 - 0.017 15.2 2.2 0.022 14.8 1.6 1.6 1 1 0 1 1 1 0 MASE2 domain Bax1-I PF01027.20 OAJ16751.1 - 0.018 14.9 5.7 0.024 14.4 5.7 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Tmemb_14 PF03647.13 OAJ16752.1 - 6e-16 59.0 10.1 6.9e-16 58.8 10.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF155 PF02582.14 OAJ16753.1 - 2.1e-49 168.0 0.0 3.4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 COLFI PF01410.18 OAJ16754.1 - 0.03 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain VHS PF00790.19 OAJ16755.1 - 2e-35 121.7 1.7 2.8e-35 121.2 0.0 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 OAJ16755.1 - 5.3e-16 58.5 9.1 1e-15 57.6 9.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 OAJ16755.1 - 6.9e-05 23.0 2.2 0.00014 22.1 2.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.20 OAJ16755.1 - 0.00073 19.3 8.8 0.038 13.9 1.9 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF3602 PF12223.8 OAJ16755.1 - 0.0015 19.1 0.3 0.0092 16.6 0.3 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) zf-RING_5 PF14634.6 OAJ16755.1 - 1.1 9.3 11.5 1.8 8.6 11.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain OAD_gamma PF04277.13 OAJ16755.1 - 1.6 9.3 3.1 3 8.5 0.0 3.1 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DDE_Tnp_4 PF13359.6 OAJ16790.1 - 5.4e-21 74.9 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ16790.1 - 2.6e-05 24.0 0.6 0.015 14.9 0.0 3.3 3 0 0 3 3 3 2 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 OAJ16791.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3425 PF11905.8 OAJ16792.1 - 2.6e-08 33.9 0.2 1.2e-07 31.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 OAJ16792.1 - 1.6e-07 31.3 5.4 4.5e-07 29.9 5.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ16792.1 - 1.9 8.6 7.7 1 9.5 3.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Epimerase PF01370.21 OAJ16827.1 - 0.0002 20.9 0.0 0.00054 19.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ16827.1 - 0.0059 16.5 0.5 0.017 15.0 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 OAJ16827.1 - 0.04 13.0 0.0 0.24 10.5 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 OAJ16827.1 - 0.09 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Nop14 PF04147.12 OAJ16828.1 - 8e-270 897.9 4.5 1.2e-269 897.2 4.5 1.2 1 0 0 1 1 1 1 Nop14-like family 2OG-FeII_Oxy_3 PF13640.6 OAJ16861.1 - 3.9e-06 27.6 0.0 8.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Exc PF07825.11 OAJ16861.1 - 0.12 12.4 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein PACT_coil_coil PF10495.9 OAJ16862.1 - 2.8e-14 53.4 0.1 2.8e-14 53.4 0.1 3.5 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 OAJ16862.1 - 0.3 11.1 88.1 0.49 10.4 2.1 6.2 3 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Collagen PF01391.18 OAJ16863.1 - 4.2e-20 71.3 72.0 2.9e-08 33.3 23.0 3.2 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) zf-BED PF02892.15 OAJ16896.1 - 0.099 12.7 1.5 0.21 11.6 1.5 1.5 1 0 0 1 1 1 0 BED zinc finger Dimer_Tnp_hAT PF05699.14 OAJ16897.1 - 6.4e-13 48.3 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BUD22 PF09073.10 OAJ16897.1 - 0.12 11.7 16.0 0.21 10.9 16.0 1.3 1 0 0 1 1 1 0 BUD22 DUF4413 PF14372.6 OAJ16897.1 - 0.14 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Pkinase PF00069.25 OAJ16898.1 - 6.1e-43 147.1 0.0 7.8e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ16898.1 - 1.2e-23 83.8 0.0 1.7e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_HII PF01351.18 OAJ16987.1 - 7.2e-44 150.0 0.0 1.9e-39 135.6 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII FXMRP1_C_core PF12235.8 OAJ16987.1 - 0.047 14.3 5.3 0.15 12.7 5.3 1.8 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal CD52 PF15116.6 OAJ16987.1 - 6 7.0 8.1 12 6.0 1.2 3.0 2 0 0 2 2 2 0 CAMPATH-1 antigen DNA_pol_A_exo1 PF01612.20 OAJ16988.1 - 8.7e-38 129.8 0.1 1.3e-37 129.2 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 OAJ16988.1 - 7.9e-20 71.3 0.1 9.1e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 OAJ16988.1 - 1.1e-11 44.5 0.2 2.3e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 HRDC domain Pox_Ag35 PF03286.14 OAJ17019.1 - 0.00071 19.4 13.0 0.001 18.9 13.0 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein DUF4820 PF16091.5 OAJ17019.1 - 0.017 14.5 4.0 0.029 13.7 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Nop14 PF04147.12 OAJ17019.1 - 0.02 13.1 21.6 0.025 12.8 21.6 1.1 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.9 OAJ17019.1 - 0.022 13.8 6.9 0.038 13.0 6.9 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myb_DNA-bind_3 PF12776.7 OAJ17019.1 - 0.025 15.6 0.1 0.042 14.8 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain CCDC106 PF15794.5 OAJ17019.1 - 0.071 12.8 6.4 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 RR_TM4-6 PF06459.12 OAJ17019.1 - 0.076 12.8 8.9 0.11 12.3 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 OAJ17019.1 - 0.15 12.0 12.0 0.18 11.8 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 OAJ17019.1 - 0.19 11.1 22.4 0.36 10.2 22.4 1.4 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 OAJ17019.1 - 0.28 10.5 16.6 0.54 9.6 16.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TLP-20 PF06088.11 OAJ17019.1 - 0.32 10.9 5.4 0.58 10.0 5.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Serinc PF03348.15 OAJ17019.1 - 0.36 9.7 0.6 0.41 9.5 0.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Astro_capsid_p PF12226.8 OAJ17019.1 - 0.37 9.9 13.5 0.47 9.6 13.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF913 PF06025.12 OAJ17019.1 - 0.48 9.3 5.8 0.72 8.8 5.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 OAJ17019.1 - 0.65 8.7 5.3 0.71 8.6 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 OAJ17019.1 - 0.74 10.2 8.6 5 7.5 8.6 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 OAJ17019.1 - 0.87 8.3 5.9 1.1 8.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 OAJ17019.1 - 0.93 7.9 25.0 1.4 7.3 25.0 1.1 1 0 0 1 1 1 0 Mpp10 protein NARP1 PF12569.8 OAJ17019.1 - 0.95 8.3 9.0 1.4 7.7 9.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 OAJ17019.1 - 1.4 8.9 15.2 2.6 8.0 15.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MAJIN PF15077.6 OAJ17019.1 - 1.8 8.3 5.7 0.81 9.4 3.4 1.6 2 0 0 2 2 2 0 Membrane-anchored junction protein Nucleo_P87 PF07267.11 OAJ17019.1 - 2.4 6.9 8.0 3.4 6.4 8.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Zip PF02535.22 OAJ17019.1 - 2.5 7.3 4.5 3.4 6.8 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BSP_II PF05432.11 OAJ17019.1 - 2.5 7.7 29.5 1.5 8.4 27.7 1.5 2 0 0 2 2 1 0 Bone sialoprotein II (BSP-II) FancD2 PF14631.6 OAJ17019.1 - 2.9 5.2 4.1 3.5 4.9 4.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Connexin PF00029.19 OAJ17019.1 - 2.9 7.6 4.4 4.9 6.8 4.4 1.3 1 0 0 1 1 1 0 Connexin FYDLN_acid PF09538.10 OAJ17019.1 - 3 8.6 22.3 6.6 7.5 22.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TFB6 PF17110.5 OAJ17019.1 - 3.6 7.3 11.0 6.8 6.4 11.0 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH MRNIP PF15749.5 OAJ17019.1 - 4 8.2 9.2 9.5 7.0 9.2 1.6 1 0 0 1 1 1 0 MRN-interacting protein NPR3 PF03666.13 OAJ17019.1 - 5.5 5.7 9.5 8.1 5.1 9.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 OAJ17019.1 - 7.6 5.2 10.4 12 4.6 10.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 OAJ17019.1 - 7.7 6.8 13.7 17 5.7 13.7 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.8 OAJ17019.1 - 8.9 6.5 31.7 22 5.2 31.7 1.7 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Merozoite_SPAM PF07133.11 OAJ17019.1 - 9.8 6.1 36.3 19 5.2 36.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PAF-AH_p_II PF03403.13 OAJ17059.1 - 1.3e-37 129.2 0.0 8.3e-20 70.6 0.2 3.0 2 2 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 OAJ17059.1 - 0.035 13.4 1.1 0.8 8.9 0.1 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 OAJ17059.1 - 0.079 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme HSP70 PF00012.20 OAJ17060.1 - 0 1163.3 17.1 6.6e-262 870.0 11.3 3.0 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 OAJ17060.1 - 4.9e-25 88.0 5.5 1.2e-12 47.4 0.6 3.4 3 0 0 3 3 3 3 MreB/Mbl protein DDR PF08841.10 OAJ17060.1 - 0.0098 14.9 0.5 5.3 5.9 0.0 2.9 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 OAJ17060.1 - 0.014 14.6 7.2 2.1 7.5 0.9 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.6 OAJ17060.1 - 0.038 14.4 10.6 2.6 8.5 0.2 4.5 4 1 0 4 4 4 0 Cell division protein FtsA Seryl_tRNA_N PF02403.22 OAJ17060.1 - 0.048 13.9 7.6 0.13 12.5 7.6 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Transcrip_reg PF01709.20 OAJ17060.1 - 0.42 10.0 9.1 0.06 12.8 3.7 2.2 3 0 0 3 3 3 0 Transcriptional regulator TAF4 PF05236.14 OAJ17060.1 - 0.56 9.9 8.4 1.9 8.1 8.4 1.9 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family NrfD PF03916.14 OAJ17061.1 - 0.019 14.6 6.5 0.063 12.9 0.3 2.0 1 1 1 2 2 2 0 Polysulphide reductase, NrfD Vps8 PF12816.7 OAJ17126.1 - 9.1e-60 201.6 0.0 1.5e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 OAJ17126.1 - 0.014 15.2 0.1 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 OAJ17126.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Kin17_mid PF10357.9 OAJ17127.1 - 2.2e-45 153.6 0.0 4.2e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 OAJ17127.1 - 0.078 13.3 2.4 0.14 12.5 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 OAJ17127.1 - 0.15 12.4 1.3 0.23 11.8 0.1 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CCDC106 PF15794.5 OAJ17127.1 - 1.8 8.3 8.2 0.44 10.2 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 SPX PF03105.19 OAJ17127.1 - 8.7 6.1 15.0 15 5.4 15.0 1.3 1 0 0 1 1 1 0 SPX domain Mito_carr PF00153.27 OAJ17157.1 - 7.2e-62 205.3 4.0 4.1e-21 74.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4471 PF14740.6 OAJ17159.1 - 0.29 10.3 7.5 0.69 9.1 7.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Proteasome PF00227.26 OAJ17160.1 - 4.3e-51 173.1 0.0 5.5e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ17160.1 - 3.2e-11 42.7 0.1 5.5e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature VPS9 PF02204.18 OAJ17187.1 - 7.7e-19 67.8 0.0 1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Transferase PF02458.15 OAJ17188.1 - 9.8e-11 40.9 0.0 0.0016 17.2 0.0 3.1 3 0 0 3 3 3 3 Transferase family SpoVR PF04293.13 OAJ17220.1 - 5.6 5.5 9.0 8.9 4.9 9.0 1.2 1 0 0 1 1 1 0 SpoVR like protein VSG_B PF13206.6 OAJ17220.1 - 6 6.0 13.9 12 5.0 13.9 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain MFS_1 PF07690.16 OAJ17221.1 - 1.9e-38 132.3 39.7 1.9e-38 132.3 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec8_exocyst PF04048.14 OAJ17222.1 - 0.19 11.6 3.7 0.41 10.5 0.3 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF16 PF01519.16 OAJ17222.1 - 1.2 9.7 11.4 0.45 11.0 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function DUF16 Sin_N PF04801.13 OAJ17253.1 - 1.3e-19 70.8 0.0 1e-16 61.2 0.0 2.2 2 0 0 2 2 2 2 Sin-like protein conserved region RNase_PH PF01138.21 OAJ17254.1 - 2.5e-15 57.1 0.0 5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_S9_N PF02897.15 OAJ17255.1 - 1.9e-76 257.5 0.1 2.4e-76 257.2 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 OAJ17255.1 - 8.3e-46 156.1 0.0 1.5e-45 155.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Adap_comp_sub PF00928.21 OAJ17256.1 - 2.6e-37 128.7 0.0 8.3e-37 127.0 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family zf-RING_11 PF17123.5 OAJ17290.1 - 4.2e-05 23.2 3.0 0.043 13.6 0.1 2.4 2 0 0 2 2 2 2 RING-like zinc finger EI24 PF07264.11 OAJ17290.1 - 0.085 13.1 6.1 0.19 11.9 4.3 2.3 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DAGK_cat PF00781.24 OAJ17291.1 - 9.7e-12 44.6 0.0 3.7e-11 42.7 0.0 1.9 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain zf-C2H2_11 PF16622.5 OAJ17326.1 - 0.019 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type NOA36 PF06524.12 OAJ17326.1 - 0.47 9.7 3.9 0.9 8.8 3.9 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ17326.1 - 1.4 7.1 3.2 2 6.6 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 OAJ17326.1 - 4.3 7.2 6.4 0.92 9.4 2.7 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.6 OAJ17326.1 - 4.5 7.7 10.2 7.1 7.1 7.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med21 PF11221.8 OAJ17327.1 - 0.011 16.0 7.0 0.04 14.2 7.0 2.0 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Atg14 PF10186.9 OAJ17327.1 - 0.018 14.1 1.9 0.03 13.4 1.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pex14_N PF04695.13 OAJ17327.1 - 0.16 12.6 12.1 0.036 14.7 7.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exonuc_VII_L PF02601.15 OAJ17327.1 - 0.37 10.3 5.6 0.57 9.7 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spt20 PF12090.8 OAJ17327.1 - 1.7 8.2 18.1 0.16 11.6 12.9 1.8 2 0 0 2 2 2 0 Spt20 family CPSF_A PF03178.15 OAJ17359.1 - 5.7e-65 219.7 0.1 9e-65 219.1 0.1 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 OAJ17359.1 - 4.2e-08 32.3 0.0 1.2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term N2227 PF07942.12 OAJ17360.1 - 1.4e-87 293.4 0.0 1.9e-87 292.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein PSII_Pbs27 PF13326.6 OAJ17360.1 - 0.024 14.9 0.1 0.085 13.2 0.0 2.0 3 0 0 3 3 3 0 Photosystem II Pbs27 Tho2 PF11262.8 OAJ17360.1 - 0.59 9.3 2.6 1.1 8.4 1.0 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4602 PF15375.6 OAJ17360.1 - 1.2 9.5 7.2 2.7 8.3 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Sec2p PF06428.11 OAJ17394.1 - 0.02 14.8 4.0 0.052 13.5 4.0 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p PE PF00934.20 OAJ17394.1 - 0.021 15.1 5.4 0.25 11.7 1.9 2.9 1 1 2 3 3 3 0 PE family Apolipoprotein PF01442.18 OAJ17394.1 - 0.077 12.9 7.3 0.16 11.8 7.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Dad2 PF08654.10 OAJ17394.1 - 0.1 13.0 0.7 0.1 13.0 0.7 2.4 2 1 1 3 3 3 0 DASH complex subunit Dad2 DUF883 PF05957.13 OAJ17394.1 - 0.25 12.0 5.9 3.6 8.2 1.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3138 PF11336.8 OAJ17394.1 - 1.5 7.3 5.8 1.7 7.1 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Retrotran_gag_2 PF14223.6 OAJ17395.1 - 0.097 12.3 0.3 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SUV3_C PF12513.8 OAJ17395.1 - 0.14 12.1 0.1 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal DDE_Tnp_1_6 PF13751.6 OAJ17395.1 - 1.5 9.1 5.5 0.25 11.6 0.7 1.9 2 0 0 2 2 2 0 Transposase DDE domain Myb_DNA-bind_4 PF13837.6 OAJ17396.1 - 0.032 14.6 0.1 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain T2SSF PF00482.23 OAJ17396.1 - 0.041 13.8 0.4 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Histone_HNS PF00816.21 OAJ17396.1 - 0.13 13.1 1.4 0.4 11.5 0.5 2.3 2 0 0 2 2 2 0 H-NS histone family FUSC PF04632.12 OAJ17396.1 - 3.2 6.2 6.1 5.5 5.4 3.7 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Nup35_RRM PF05172.13 OAJ17431.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ASFV_L11L PF05293.11 OAJ17431.1 - 2.4 8.6 3.9 0.79 10.1 0.1 2.2 3 0 0 3 3 3 0 African swine fever virus (ASFV) L11L protein DUF5102 PF17104.5 OAJ17464.1 - 2.5e-39 136.0 0.0 7.3e-39 134.5 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) SIS PF01380.22 OAJ17465.1 - 5.3e-65 217.2 0.2 6.4e-36 123.1 0.0 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 OAJ17465.1 - 2.2e-15 57.0 0.0 4.7e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ17465.1 - 1.7e-11 44.1 0.0 3.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 OAJ17465.1 - 0.0024 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TTRAP PF14203.6 OAJ17465.1 - 0.018 15.0 0.4 0.2 11.7 0.1 2.7 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein SIS_2 PF13580.6 OAJ17465.1 - 0.093 12.8 0.0 0.97 9.4 0.0 2.7 3 1 1 4 4 4 0 SIS domain YoeB_toxin PF06769.14 OAJ17465.1 - 0.18 11.9 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system P16-Arc PF04699.14 OAJ17466.1 - 1e-49 168.8 0.0 1.2e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ras PF00071.22 OAJ17500.1 - 8.8e-28 96.9 0.0 1.7e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 OAJ17500.1 - 8.6e-26 90.5 0.0 1.4e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17500.1 - 0.00017 21.1 0.0 0.00029 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ17500.1 - 0.0036 17.4 0.0 0.0071 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 OAJ17500.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Cation_efflux PF01545.21 OAJ17501.1 - 5e-18 65.5 10.8 6.3e-18 65.2 10.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ17501.1 - 2.8e-05 24.1 0.0 4.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter CUE PF02845.16 OAJ17540.1 - 0.2 11.4 0.5 29 4.5 0.0 3.3 3 0 0 3 3 3 0 CUE domain DUF1687 PF07955.11 OAJ17541.1 - 2.6e-11 44.1 1.9 9.6e-09 35.8 0.1 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1687) ATP19 PF11022.8 OAJ17581.1 - 7.7e-20 71.0 0.2 9.4e-20 70.8 0.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Cyt-b5 PF00173.28 OAJ17582.1 - 3.9e-18 65.4 0.0 5.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3530 PF12048.8 OAJ17582.1 - 0.95 8.8 5.4 1.1 8.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) HA2 PF04408.23 OAJ17583.1 - 8.9e-24 83.9 2.1 9.6e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ17583.1 - 6.3e-21 74.5 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ17583.1 - 6.3e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OAJ17583.1 - 0.00019 20.6 0.0 0.00047 19.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ17583.1 - 0.00025 21.3 0.1 0.00063 20.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ17583.1 - 0.00027 20.7 0.8 0.00056 19.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ17583.1 - 0.00071 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ17583.1 - 0.021 15.2 0.1 0.021 15.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 OAJ17583.1 - 0.052 14.1 0.3 0.52 10.8 0.3 2.4 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 OAJ17583.1 - 0.055 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ17583.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NuA4 PF09340.10 OAJ17584.1 - 2e-20 72.5 0.0 3.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Bac_surface_Ag PF01103.23 OAJ17585.1 - 3.9e-25 89.0 0.4 8.5e-25 87.9 0.4 1.5 1 1 0 1 1 1 1 Surface antigen Cyclin PF08613.11 OAJ17623.1 - 2.9e-08 34.2 0.4 6.4e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Cyclin Ras PF00071.22 OAJ17624.1 - 4e-62 208.6 0.1 4.7e-62 208.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ17624.1 - 1.1e-33 116.0 0.0 1.6e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ17624.1 - 2.5e-12 46.6 0.0 3.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ17624.1 - 5.7e-06 26.4 0.0 9.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ17624.1 - 0.00016 21.3 0.1 0.00086 18.9 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ17624.1 - 0.0012 18.8 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 OAJ17624.1 - 0.0037 17.6 0.1 0.052 13.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 OAJ17624.1 - 0.0039 17.6 0.1 0.0066 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 OAJ17624.1 - 0.0055 16.1 0.0 0.0076 15.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ17624.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 OAJ17624.1 - 0.025 14.3 0.0 0.079 12.7 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 OAJ17624.1 - 0.043 14.3 0.1 0.072 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 OAJ17624.1 - 0.043 14.1 0.2 0.31 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ17624.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ17624.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 OAJ17624.1 - 0.084 12.3 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 OAJ17624.1 - 0.086 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 OAJ17624.1 - 0.087 12.6 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OAJ17624.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AEP1 PF17049.5 OAJ17624.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 EF_assoc_2 PF08356.12 OAJ17625.1 - 6.5e-24 83.7 0.0 4.6e-23 81.0 0.0 2.3 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 OAJ17625.1 - 1.7e-20 72.4 2.2 2.4e-20 71.9 0.5 2.1 2 1 0 2 2 1 1 EF hand associated Ras PF00071.22 OAJ17625.1 - 5.5e-16 58.6 0.0 0.00032 20.3 0.0 4.9 5 0 0 5 5 5 3 Ras family Roc PF08477.13 OAJ17625.1 - 2.1e-07 31.1 0.0 0.003 17.8 0.0 4.4 5 0 0 5 5 4 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ17625.1 - 1e-06 28.8 0.0 0.00047 20.2 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase EF-hand_7 PF13499.6 OAJ17625.1 - 3.3e-06 27.4 0.4 0.046 14.2 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.6 OAJ17625.1 - 9.5e-06 25.9 0.0 0.26 11.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAJ17625.1 - 2.1e-05 24.5 0.6 0.0047 16.9 0.0 3.7 4 0 0 4 4 4 1 RsgA GTPase AAA_16 PF13191.6 OAJ17625.1 - 3.3e-05 24.4 0.5 0.052 13.9 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain ABC_tran PF00005.27 OAJ17625.1 - 5.4e-05 23.7 0.1 0.037 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter EF-hand_6 PF13405.6 OAJ17625.1 - 9.2e-05 22.1 4.9 0.063 13.2 0.2 3.0 3 0 0 3 3 2 2 EF-hand domain Dynamin_N PF00350.23 OAJ17625.1 - 0.00037 20.6 0.1 0.98 9.5 0.1 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 OAJ17625.1 - 0.00043 20.0 0.1 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AIG1 PF04548.16 OAJ17625.1 - 0.00058 19.2 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family NACHT PF05729.12 OAJ17625.1 - 0.0024 17.8 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 OAJ17625.1 - 0.0055 17.2 0.1 0.32 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ17625.1 - 0.0095 16.1 0.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ17625.1 - 0.013 15.9 0.1 0.83 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ17625.1 - 0.017 14.3 0.2 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 OAJ17625.1 - 0.025 13.9 0.0 0.088 12.1 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 OAJ17625.1 - 0.03 14.6 0.1 8.6 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ17625.1 - 0.031 13.8 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAJ17625.1 - 0.032 13.9 0.3 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ17625.1 - 0.037 13.8 0.0 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ17625.1 - 0.056 13.8 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase EF-hand_1 PF00036.32 OAJ17625.1 - 0.058 13.0 12.4 0.21 11.2 0.1 3.4 4 0 0 4 4 3 0 EF hand Viral_helicase1 PF01443.18 OAJ17625.1 - 0.078 12.7 0.0 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 OAJ17625.1 - 0.081 12.4 0.1 0.081 12.4 0.1 3.2 4 0 0 4 4 3 0 EF hand cobW PF02492.19 OAJ17625.1 - 0.12 12.0 0.2 11 5.5 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 OAJ17625.1 - 0.16 11.1 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 OAJ17625.1 - 0.2 12.2 0.2 16 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 OAJ17625.1 - 0.23 11.3 0.0 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 OAJ17625.1 - 0.24 11.1 0.3 37 4.0 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Glyco_hydro_45 PF02015.16 OAJ17656.1 - 9.1e-47 159.7 2.5 1.2e-46 159.3 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CPT PF07931.12 OAJ17657.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Na_trans_assoc PF06512.13 OAJ17658.1 - 0.0034 17.7 1.8 0.0051 17.1 1.8 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated Nop14 PF04147.12 OAJ17658.1 - 0.042 12.1 16.7 0.054 11.7 16.7 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 OAJ17658.1 - 0.22 10.9 12.6 0.32 10.4 12.6 1.2 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 OAJ17658.1 - 0.23 11.2 5.1 0.39 10.5 5.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIA PF03153.13 OAJ17658.1 - 0.28 11.1 12.5 0.38 10.7 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 OAJ17658.1 - 0.44 9.0 8.0 0.62 8.5 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2722 PF10846.8 OAJ17658.1 - 0.63 8.9 3.1 0.77 8.6 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPP4R2 PF09184.11 OAJ17658.1 - 0.73 9.4 11.3 0.57 9.7 10.0 1.5 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 OAJ17658.1 - 0.78 8.0 9.0 1.2 7.3 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ17658.1 - 0.8 9.8 19.7 0.092 12.9 14.6 1.8 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 OAJ17658.1 - 3.4 6.9 12.9 4.8 6.4 12.9 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 OAJ17658.1 - 3.6 7.4 12.0 5.5 6.8 12.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 OAJ17658.1 - 5 6.3 6.6 7.1 5.8 6.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Glyco_hydro_45 PF02015.16 OAJ17659.1 - 1.2e-51 175.7 3.4 1.4e-51 175.4 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 SelP_N PF04592.14 OAJ17659.1 - 1.3 8.4 13.8 1.9 7.8 13.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Helicase_C PF00271.31 OAJ17695.1 - 2.1e-12 47.3 0.0 6e-12 45.9 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ17695.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ17695.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SDA1 PF05285.12 OAJ17696.1 - 0.0012 18.3 8.8 0.0019 17.7 8.8 1.4 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 OAJ17696.1 - 0.0033 15.7 12.7 0.0047 15.2 12.7 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 OAJ17696.1 - 0.18 10.1 12.0 0.28 9.4 12.0 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ17696.1 - 0.22 11.6 16.2 0.56 10.3 16.2 1.6 1 0 0 1 1 1 0 YL1 nuclear protein SpoIIIAH PF12685.7 OAJ17696.1 - 5.1 6.9 11.8 2.4 8.0 7.6 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein VTC PF09359.10 OAJ17737.1 - 4.9e-97 324.6 0.2 1.8e-96 322.8 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 OAJ17737.1 - 9.4e-19 68.6 24.9 1.1e-06 28.9 0.5 4.4 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 OAJ17737.1 - 3.7e-13 49.7 0.6 9e-13 48.5 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) BRAP2 PF07576.12 OAJ17738.1 - 6.1e-27 93.8 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 OAJ17738.1 - 3.6e-17 62.4 4.5 1.1e-16 60.9 4.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 OAJ17738.1 - 2.5e-08 34.1 10.3 2.5e-08 34.1 10.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 OAJ17738.1 - 6.8e-06 26.3 6.9 6.8e-06 26.3 6.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 OAJ17738.1 - 3.5e-05 23.6 9.4 3.5e-05 23.6 9.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ17738.1 - 3.8e-05 23.6 4.5 0.00014 21.8 4.5 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ17738.1 - 0.00013 21.7 10.4 0.00013 21.7 10.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ17738.1 - 0.00026 20.7 4.1 0.00026 20.7 4.1 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 OAJ17738.1 - 0.00073 19.4 8.2 0.00073 19.4 8.2 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ17738.1 - 0.0015 18.6 4.0 0.0015 18.6 4.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 OAJ17738.1 - 0.011 15.5 7.6 0.011 15.5 7.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DEC-1_C PF04626.13 OAJ17738.1 - 0.032 14.6 4.6 0.079 13.4 4.6 1.6 1 0 0 1 1 1 0 Dec-1 protein, C terminal region zf-RING_4 PF14570.6 OAJ17738.1 - 0.049 13.4 7.0 0.11 12.3 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 OAJ17738.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAUS-augmin3 PF14932.6 OAJ17738.1 - 0.8 9.2 10.3 1.7 8.2 10.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 EzrA PF06160.12 OAJ17738.1 - 1 7.4 7.5 1.7 6.8 7.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-C3HC4_4 PF15227.6 OAJ17738.1 - 4 7.7 7.5 16 5.8 7.5 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2968 PF11180.8 OAJ17738.1 - 5.3 6.6 18.2 0.54 9.9 9.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DIM PF08194.12 OAJ17739.1 - 0.58 10.4 0.1 0.58 10.4 0.1 3.0 4 0 0 4 4 4 0 DIM protein Dimer_Tnp_hAT PF05699.14 OAJ17767.1 - 1.1e-14 53.9 0.1 3.4e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 OAJ17767.1 - 0.029 14.4 0.6 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 OAJ17768.1 - 2.5e-37 128.7 0.0 3.1e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ17768.1 - 9.6e-18 64.4 0.0 1.5e-17 63.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ17768.1 - 6.7e-07 28.9 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ17768.1 - 0.00013 22.0 0.2 0.00039 20.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ17768.1 - 0.0054 16.4 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 OAJ17768.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 OAJ17768.1 - 0.25 11.0 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 YukC PF10140.9 OAJ17768.1 - 0.26 10.1 0.0 0.36 9.6 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MULE PF10551.9 OAJ17769.1 - 7.2e-23 80.8 0.1 1.6e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain DUF5071 PF16804.5 OAJ17769.1 - 0.079 13.2 0.6 1.9 8.7 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF5071) Peptidase_C48 PF02902.19 OAJ17808.1 - 0.13 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF1134 PF06577.12 OAJ17809.1 - 0.1 12.4 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1134) GCP_C_terminal PF04130.13 OAJ17838.1 - 1.5e-42 146.1 0.0 3.1e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ17838.1 - 2.2e-09 37.4 0.0 1.6e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal XPG_I_2 PF12813.7 OAJ17839.1 - 8.5e-06 25.4 0.0 0.0021 17.5 0.0 3.1 3 0 0 3 3 3 1 XPG domain containing XPG_N PF00752.17 OAJ17839.1 - 0.00025 21.5 0.0 0.00085 19.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain K_channel_TID PF07941.11 OAJ17839.1 - 1.3 9.5 8.2 4.8 7.7 8.2 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FCH PF00611.23 OAJ17874.1 - 2.7e-16 59.6 1.8 1e-14 54.5 0.1 3.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SUIM_assoc PF16619.5 OAJ17874.1 - 0.016 15.3 3.1 0.016 15.3 3.1 4.2 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 OAJ17875.1 - 3.2e-30 105.3 27.4 3.2e-30 105.3 27.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC_tran PF00005.27 OAJ17876.1 - 1.2e-44 152.2 0.0 1.2e-23 84.1 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAJ17876.1 - 1.9e-16 60.7 0.3 0.0023 17.8 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ17876.1 - 1.9e-10 40.6 0.0 0.014 14.8 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ17876.1 - 1.4e-08 35.5 0.0 0.0013 19.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 OAJ17876.1 - 1.3e-06 28.2 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 OAJ17876.1 - 2.1e-06 27.4 0.1 0.076 12.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_EZ PF13513.6 OAJ17876.1 - 4.1e-05 24.0 6.9 5.9 7.5 0.2 6.4 5 1 0 5 5 5 1 HEAT-like repeat AAA_16 PF13191.6 OAJ17876.1 - 4.6e-05 23.9 4.0 0.027 14.9 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ17876.1 - 5e-05 23.4 0.0 0.017 15.2 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ17876.1 - 7.2e-05 23.1 0.1 1.3 9.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain HEAT PF02985.22 OAJ17876.1 - 0.00014 21.8 5.3 3 8.4 0.1 6.1 6 0 0 6 6 5 1 HEAT repeat AAA_28 PF13521.6 OAJ17876.1 - 0.00024 21.4 0.1 3.6 7.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain HEAT_2 PF13646.6 OAJ17876.1 - 0.0003 21.1 10.4 0.025 15.0 1.1 5.0 4 2 2 6 6 4 2 HEAT repeats RsgA_GTPase PF03193.16 OAJ17876.1 - 0.0016 18.4 0.2 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 OAJ17876.1 - 0.0036 17.5 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ17876.1 - 0.0042 16.8 0.2 0.86 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 OAJ17876.1 - 0.0055 16.6 0.1 3.7 7.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain MeaB PF03308.16 OAJ17876.1 - 0.0055 15.7 0.4 0.53 9.2 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Adaptin_N PF01602.20 OAJ17876.1 - 0.0056 15.3 0.7 0.13 10.8 0.7 2.5 1 1 0 1 1 1 1 Adaptin N terminal region AAA_15 PF13175.6 OAJ17876.1 - 0.0058 16.4 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Cnd1 PF12717.7 OAJ17876.1 - 0.012 15.7 0.4 1 9.4 0.0 3.1 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 AAA_24 PF13479.6 OAJ17876.1 - 0.012 15.3 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAJ17876.1 - 0.023 14.8 0.7 9.8 6.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 OAJ17876.1 - 0.046 14.3 0.1 11 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 OAJ17876.1 - 0.05 13.2 0.1 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain CLASP_N PF12348.8 OAJ17876.1 - 0.067 12.8 0.2 1.7 8.2 0.1 2.7 1 1 1 2 2 2 0 CLASP N terminal Zeta_toxin PF06414.12 OAJ17876.1 - 0.1 11.8 0.2 23 4.2 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin KAP_NTPase PF07693.14 OAJ17876.1 - 0.16 11.1 0.1 17 4.5 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain Dopey_N PF04118.14 OAJ17876.1 - 0.17 11.0 0.0 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Dopey, N-terminal RNA_helicase PF00910.22 OAJ17876.1 - 0.2 12.1 0.0 7.5 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Abhydrolase_1 PF00561.20 OAJ17908.1 - 2.2e-16 60.3 0.4 1.8e-12 47.5 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ17908.1 - 8.3e-15 56.0 0.3 1.2e-14 55.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ17908.1 - 5.2e-12 45.5 0.0 1e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ17908.1 - 0.0047 16.6 0.0 0.0064 16.2 0.0 1.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ17908.1 - 0.0048 16.7 0.0 0.19 11.5 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 OAJ17908.1 - 0.017 15.0 0.0 0.12 12.2 0.0 2.0 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 OAJ17908.1 - 0.033 14.0 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase FSH1 PF03959.13 OAJ17908.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CybS PF05328.12 OAJ17909.1 - 7.6e-41 138.9 0.0 1.1e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit START PF01852.19 OAJ17910.1 - 0.0039 16.6 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 START domain Ion_trans PF00520.31 OAJ17911.1 - 0.00036 19.8 0.1 0.00059 19.1 0.1 1.3 1 1 0 1 1 1 1 Ion transport protein IMS PF00817.20 OAJ17948.1 - 7.6e-30 103.9 0.0 1.4e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ17948.1 - 1.1e-05 26.1 0.0 5.8e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ17948.1 - 0.035 14.4 0.0 0.084 13.2 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Nuf2 PF03800.14 OAJ17948.1 - 0.038 14.1 0.0 0.097 12.8 0.0 1.6 2 0 0 2 2 2 0 Nuf2 family PI3K_1B_p101 PF10486.9 OAJ17948.1 - 0.84 7.3 8.4 1.3 6.7 8.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit HSCB_C PF07743.13 OAJ17949.1 - 1.4e-18 67.2 0.6 1.4e-18 67.2 0.6 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 OAJ17949.1 - 2.7e-06 27.4 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain cwf21 PF08312.12 OAJ17949.1 - 0.017 15.2 1.1 0.043 14.0 1.1 1.7 1 0 0 1 1 1 0 cwf21 domain EF-hand_1 PF00036.32 OAJ17950.1 - 3e-27 92.1 13.2 2.8e-08 32.7 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ17950.1 - 9.1e-21 72.0 8.9 0.0001 22.0 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 OAJ17950.1 - 2.5e-19 69.5 9.7 3.7e-13 49.7 2.6 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ17950.1 - 1.1e-17 62.7 14.2 4e-06 26.1 1.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 OAJ17950.1 - 4e-13 49.0 14.5 0.0036 17.1 2.0 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 OAJ17950.1 - 4.8e-05 23.3 6.4 0.0045 16.9 0.9 3.4 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ17950.1 - 0.00048 20.4 0.2 0.23 11.8 0.2 3.0 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ17950.1 - 0.0006 20.1 0.0 0.015 15.6 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.6 OAJ17950.1 - 0.071 13.7 1.3 9.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SelR PF01641.18 OAJ17951.1 - 1.6e-50 170.2 0.1 2.2e-50 169.8 0.1 1.2 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.6 OAJ17951.1 - 0.1 12.7 2.4 0.14 12.3 0.3 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Thymidylat_synt PF00303.19 OAJ17980.1 - 1.4e-27 96.5 0.0 1.9e-27 96.1 0.0 1.5 1 1 0 1 1 1 1 Thymidylate synthase DUF5063 PF16702.5 OAJ17980.1 - 0.089 13.2 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5063) Cyclin_N PF00134.23 OAJ17981.1 - 1.8e-36 124.7 0.1 4.9e-36 123.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ17981.1 - 3.8e-11 43.1 0.5 1.2e-10 41.6 0.5 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain NOA36 PF06524.12 OAJ17981.1 - 0.35 10.1 4.3 0.53 9.6 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 OAJ17981.1 - 1.1 7.3 7.1 1 7.3 5.2 1.8 2 0 0 2 2 2 0 DNA polymerase phi SPT2 PF08243.11 OAJ17981.1 - 1.7 9.2 8.0 4.8 7.8 8.0 1.7 1 0 0 1 1 1 0 SPT2 chromatin protein Raftlin PF15250.6 OAJ17981.1 - 9.8 4.8 11.5 0.085 11.6 0.8 2.1 2 0 0 2 2 2 0 Raftlin DUF2256 PF10013.9 OAJ18014.1 - 4.7e-14 52.2 4.5 8.6e-14 51.4 4.5 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Sugar_tr PF00083.24 OAJ18015.1 - 1.4e-39 136.2 21.4 4.2e-38 131.4 21.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ18015.1 - 3.1e-16 59.3 39.6 8.9e-12 44.6 35.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ18015.1 - 8.9e-06 24.5 5.7 8.9e-06 24.5 5.7 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein BT1 PF03092.16 OAJ18015.1 - 0.0033 15.7 1.0 0.74 8.0 0.0 2.5 2 0 0 2 2 2 2 BT1 family Baculo_PEP_C PF04513.12 OAJ18016.1 - 4.8e-05 23.4 11.1 0.0016 18.5 0.4 3.5 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Het-C PF07217.11 OAJ18016.1 - 0.0033 16.0 0.6 0.0033 16.0 0.6 1.7 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C STAT_alpha PF01017.20 OAJ18016.1 - 0.005 16.8 3.6 0.18 11.7 0.3 2.4 2 0 0 2 2 2 1 STAT protein, all-alpha domain Syntaxin PF00804.25 OAJ18016.1 - 0.011 15.4 5.0 0.18 11.4 1.1 2.2 2 0 0 2 2 2 0 Syntaxin Filament PF00038.21 OAJ18016.1 - 0.032 13.8 1.3 4.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein PIN_2 PF10130.9 OAJ18016.1 - 0.059 13.6 1.0 1.6 9.0 0.2 2.6 2 0 0 2 2 2 0 PIN domain HAUS-augmin3 PF14932.6 OAJ18016.1 - 0.062 12.9 10.0 0.049 13.2 2.3 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Syntaxin-6_N PF09177.11 OAJ18016.1 - 0.079 13.5 3.7 2.9 8.5 0.8 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 OAJ18016.1 - 0.14 12.9 5.6 0.15 12.8 1.4 2.3 2 0 0 2 2 2 0 Occludin homology domain DUF4634 PF15465.6 OAJ18016.1 - 0.16 12.3 0.4 0.34 11.2 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4634) RmuC PF02646.16 OAJ18016.1 - 0.27 10.3 6.8 0.66 9.0 2.7 2.3 2 0 0 2 2 2 0 RmuC family TMPIT PF07851.13 OAJ18016.1 - 0.69 9.1 5.9 2.8 7.1 0.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 OAJ18016.1 - 0.74 9.9 8.1 1.9 8.6 1.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 OAJ18016.1 - 0.85 9.8 4.4 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SurA_N_3 PF13624.6 OAJ18016.1 - 1.2 8.8 4.9 0.25 11.1 0.4 2.0 3 0 0 3 3 3 0 SurA N-terminal domain APG6_N PF17675.1 OAJ18016.1 - 1.3 9.5 9.5 5.3 7.6 1.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 OAJ18016.1 - 1.4 8.5 8.6 0.32 10.6 0.4 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HIP1_clath_bdg PF16515.5 OAJ18016.1 - 1.7 9.3 8.7 5.1 7.8 0.9 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Carbpep_Y_N PF05388.11 OAJ18016.1 - 2.9 8.5 6.1 2 8.9 1.9 2.5 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide RRN3 PF05327.11 OAJ18016.1 - 4.2 5.8 6.4 13 4.2 1.9 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Seryl_tRNA_N PF02403.22 OAJ18016.1 - 5.3 7.3 8.8 9.3 6.5 0.6 2.8 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain YlqD PF11068.8 OAJ18016.1 - 6.9 7.0 10.0 18 5.7 2.3 2.6 2 0 0 2 2 2 0 YlqD protein Lectin_N PF03954.14 OAJ18016.1 - 7.6 6.3 8.4 5.2 6.8 1.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain RT_RNaseH_2 PF17919.1 OAJ18062.1 - 7.1e-24 83.8 0.1 4.3e-14 52.4 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ18062.1 - 3.1e-18 66.0 0.0 1.6e-12 47.6 0.0 2.9 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18062.1 - 1.4e-15 57.2 0.0 3e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18062.1 - 4.2e-12 46.3 0.0 1.5e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ18062.1 - 3.8e-07 29.9 0.0 6.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ18064.1 - 6.2e-22 77.5 0.1 2.4e-13 50.0 0.1 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ18064.1 - 6.9e-22 78.0 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ18064.1 - 1.7e-16 60.4 0.0 3.2e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18064.1 - 8.3e-15 54.6 0.0 1.6e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18064.1 - 1.4e-11 44.6 0.0 3.9e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ18064.1 - 0.007 17.0 0.1 0.032 14.9 0.1 2.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ18064.1 - 0.04 14.5 0.0 0.2 12.3 0.0 2.2 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease Herpes_ORF11 PF04797.13 OAJ18064.1 - 0.12 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RVT_1 PF00078.27 OAJ18100.1 - 3.5e-24 85.5 0.0 6.3e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ18100.1 - 6.8e-22 77.4 0.0 1.7e-12 47.2 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ18100.1 - 5.8e-17 61.9 0.0 6.8e-12 45.6 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ18100.1 - 3.3e-12 46.3 0.1 6.1e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ18100.1 - 2e-09 37.6 0.0 4.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ18100.1 - 0.0071 17.0 0.0 0.025 15.2 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease zf-H2C2 PF09337.10 OAJ18100.1 - 0.045 14.0 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 H2C2 zinc finger RVT_3 PF13456.6 OAJ18138.1 - 0.0023 17.7 0.2 0.0047 16.7 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ18138.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Phage_integrase PF00589.22 OAJ18139.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family LIP PF03583.14 OAJ18140.1 - 2.6e-39 135.3 0.3 1.1e-37 129.9 0.3 2.1 1 1 0 1 1 1 1 Secretory lipase RAI16-like PF10257.9 OAJ18178.1 - 1.8e-07 30.4 0.0 1.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DNA_pol_phi PF04931.13 OAJ18179.1 - 0.0017 16.6 5.2 0.0017 16.6 5.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 OAJ18179.1 - 0.0068 14.7 4.0 0.0068 14.7 4.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 OAJ18179.1 - 0.0077 15.4 7.9 0.008 15.4 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.14 OAJ18179.1 - 0.0089 14.4 2.2 0.01 14.2 2.2 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OAJ18179.1 - 0.014 14.9 3.7 0.015 14.8 3.7 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ18179.1 - 0.019 14.3 5.0 0.02 14.3 5.0 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 OAJ18179.1 - 0.021 12.9 3.2 0.021 12.9 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 OAJ18179.1 - 0.048 12.2 1.1 0.054 12.0 1.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Radial_spoke PF04712.12 OAJ18179.1 - 0.065 12.2 3.1 0.082 11.8 3.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CENP-B_dimeris PF09026.10 OAJ18179.1 - 0.073 13.5 15.0 0.13 12.7 15.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Apt1 PF10351.9 OAJ18179.1 - 0.091 11.6 0.5 0.095 11.5 0.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-3c_N PF05470.12 OAJ18179.1 - 0.1 10.9 1.9 0.11 10.7 1.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus XAP5 PF04921.14 OAJ18179.1 - 0.17 11.7 1.6 0.21 11.4 1.6 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM176 PF14851.6 OAJ18179.1 - 0.23 11.1 5.0 0.32 10.7 5.0 1.3 1 0 0 1 1 1 0 FAM176 family DUF2967 PF11179.8 OAJ18179.1 - 0.28 9.2 5.9 0.32 9.0 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4207 PF13904.6 OAJ18179.1 - 0.37 10.5 2.2 0.47 10.1 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4746 PF15928.5 OAJ18179.1 - 0.37 10.2 3.5 0.48 9.8 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PAC1 PF16094.5 OAJ18179.1 - 0.44 9.7 4.4 0.65 9.1 4.4 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 ANAPC9 PF12856.7 OAJ18179.1 - 0.64 10.2 5.5 1.1 9.5 5.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 NOA36 PF06524.12 OAJ18179.1 - 0.66 9.2 12.6 0.85 8.9 12.6 1.1 1 0 0 1 1 1 0 NOA36 protein PI3K_1B_p101 PF10486.9 OAJ18179.1 - 0.98 7.1 3.6 1.1 6.9 3.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.6 OAJ18179.1 - 1.2 9.5 10.2 2.2 8.7 9.7 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_12 PF13424.6 OAJ18180.1 - 9.4e-06 25.8 22.1 1.3 9.3 0.0 7.3 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ18180.1 - 7.7e-05 22.5 10.9 1.5 9.1 2.2 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ18180.1 - 0.00069 19.8 6.6 7.8 6.8 0.0 5.6 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ18180.1 - 0.00082 20.0 11.9 2.8 9.0 0.0 6.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ18180.1 - 0.0049 17.2 1.5 13 6.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ18180.1 - 0.0084 16.2 0.1 0.091 12.8 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 OAJ18180.1 - 0.026 14.4 17.6 0.79 9.7 1.2 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18180.1 - 0.03 14.1 9.1 1.7 8.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18180.1 - 0.035 14.3 5.3 6.8 7.2 0.5 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAJ18180.1 - 0.054 13.6 2.1 15 5.8 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 OAJ18180.1 - 0.094 12.8 7.3 22 5.3 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18180.1 - 0.11 13.2 7.8 59 4.4 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ18180.1 - 0.19 12.4 13.9 0.21 12.3 0.5 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ18180.1 - 1.5 9.4 18.9 24 5.5 0.8 7.4 6 2 1 7 7 7 0 Tetratricopeptide repeat RNase_PH PF01138.21 OAJ18213.1 - 1.6e-19 70.7 0.0 3.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ18213.1 - 3.8e-05 23.6 0.0 9.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3889 PF13028.6 OAJ18213.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) TPR_1 PF00515.28 OAJ18214.1 - 7.8e-45 148.9 28.9 2.5e-05 23.9 0.2 10.0 10 0 0 10 10 9 9 Tetratricopeptide repeat STI1 PF17830.1 OAJ18214.1 - 6.6e-34 115.6 14.0 7.6e-18 64.2 0.7 3.5 3 0 0 3 3 3 2 STI1 domain TPR_2 PF07719.17 OAJ18214.1 - 1.2e-30 103.1 34.4 0.0072 16.4 0.1 10.1 11 0 0 11 11 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ18214.1 - 8.2e-22 75.5 28.8 0.0022 18.1 0.0 9.8 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ18214.1 - 4.8e-21 74.2 28.4 5.8e-06 25.9 0.4 9.3 7 2 2 9 9 9 6 TPR repeat TPR_12 PF13424.6 OAJ18214.1 - 3.9e-18 65.5 26.6 3.2e-10 40.2 0.5 7.1 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ18214.1 - 4.7e-15 55.0 18.7 0.074 13.9 0.0 9.6 3 3 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ18214.1 - 2.8e-14 53.5 34.9 1.1e-05 26.0 1.5 8.1 4 3 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ18214.1 - 4.4e-09 36.7 23.2 3.6e-05 24.2 0.4 6.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ18214.1 - 3e-08 33.5 6.5 0.04 14.3 0.1 6.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ18214.1 - 1.2e-07 31.3 9.8 0.016 15.2 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ18214.1 - 8.7e-07 28.6 18.2 1.8 8.5 0.1 8.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ18214.1 - 2.6e-06 27.5 9.1 0.027 14.6 0.1 5.2 3 2 2 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ18214.1 - 0.00014 22.3 18.7 0.87 10.4 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 OAJ18214.1 - 0.011 14.5 0.0 0.011 14.5 0.0 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 OAJ18214.1 - 0.02 15.1 2.5 0.02 15.1 2.5 4.2 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 OAJ18214.1 - 0.045 13.8 3.0 4.5 7.4 0.1 3.5 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.11 OAJ18214.1 - 0.1 12.3 5.8 0.3 10.8 3.2 3.0 3 0 0 3 3 3 0 XPC-binding domain Coat_F PF07875.12 OAJ18214.1 - 0.31 11.3 2.1 0.8 10.0 0.1 2.7 2 0 0 2 2 2 0 Coat F domain DUF3856 PF12968.7 OAJ18214.1 - 0.39 10.8 11.2 11 6.1 1.7 4.9 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) Ribosomal_S13 PF00416.22 OAJ18215.1 - 2.1e-51 173.6 1.9 2.4e-51 173.5 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 OAJ18215.1 - 0.016 15.5 0.1 0.051 13.8 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif FbpA PF05833.11 OAJ18215.1 - 0.032 13.0 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2746 PF10874.8 OAJ18215.1 - 0.068 13.6 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) WD40 PF00400.32 OAJ18216.1 - 1.1e-14 54.6 0.7 0.011 16.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18216.1 - 9.1e-08 32.3 0.0 0.028 14.7 0.0 4.7 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain ARHGEF5_35 PF15441.6 OAJ18216.1 - 0.072 12.1 1.0 0.1 11.6 1.0 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DEAD PF00270.29 OAJ18249.1 - 4.8e-32 111.1 0.0 9.5e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ18249.1 - 4.3e-29 101.1 0.0 1.2e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ18249.1 - 0.00062 19.8 0.0 0.00062 19.8 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Utp14 PF04615.13 OAJ18249.1 - 0.00086 18.0 26.6 0.0014 17.4 26.6 1.2 1 0 0 1 1 1 1 Utp14 protein Cwf_Cwc_15 PF04889.12 OAJ18249.1 - 0.0087 15.8 30.5 0.0087 15.8 30.5 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DnaI_N PF07319.11 OAJ18249.1 - 0.015 16.0 0.4 0.99 10.1 0.0 2.7 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Apt1 PF10351.9 OAJ18249.1 - 2.8 6.7 17.4 0.17 10.7 11.1 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain BUD22 PF09073.10 OAJ18249.1 - 8.4 5.6 44.7 16 4.7 44.7 1.4 1 0 0 1 1 1 0 BUD22 RhoGAP PF00620.27 OAJ18250.1 - 5.8e-45 152.8 0.0 1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 OAJ18250.1 - 5.6e-17 61.8 1.0 1.5e-16 60.4 0.3 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PDEase_II PF02112.15 OAJ18251.1 - 1.3e-37 129.7 0.0 6.1e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 cAMP phosphodiesterases class-II EPL1 PF10513.9 OAJ18251.1 - 0.63 10.4 3.7 3.8 7.9 0.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like SelP_N PF04592.14 OAJ18251.1 - 1.9 7.9 12.5 3.9 6.8 12.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP70 PF00012.20 OAJ18291.1 - 6.5e-23 80.8 0.4 7.6e-23 80.5 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein ASF1_hist_chap PF04729.13 OAJ18291.1 - 0.0078 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone STATa_Ig PF18214.1 OAJ18291.1 - 0.053 13.5 0.8 5.6 7.0 0.1 2.1 1 1 1 2 2 2 0 STATa Immunoglobulin-like domain MmgE_PrpD PF03972.14 OAJ18292.1 - 6e-75 252.5 0.3 3e-41 141.4 0.0 2.0 1 1 1 2 2 2 2 MmgE/PrpD family MmgE_PrpD PF03972.14 OAJ18293.1 - 5.9e-10 38.3 0.0 6.9e-10 38.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DEC-1_N PF04625.13 OAJ18368.1 - 1.7 7.5 7.8 1.7 7.5 7.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RNase_H PF00075.24 OAJ18370.1 - 0.059 13.5 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 RNase H RVT_3 PF13456.6 OAJ18370.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF5339 PF17274.2 OAJ18402.1 - 2.9 8.8 5.7 0.79 10.6 1.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Na_Ca_ex PF01699.24 OAJ18403.1 - 8.9e-41 139.3 39.6 1e-20 74.2 13.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RNA_pol_Rpb4 PF03874.16 OAJ18404.1 - 1e-10 42.0 0.2 1.6e-10 41.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Urease_linker PF18473.1 OAJ18404.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain Mito_carr PF00153.27 OAJ18441.1 - 2.5e-29 101.0 4.5 7.9e-15 54.6 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein B12D PF06522.11 OAJ18442.1 - 2.3e-17 62.6 0.0 2.5e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_EFTU PF00009.27 OAJ18443.1 - 3e-45 154.2 0.1 6.3e-45 153.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ18443.1 - 8e-31 106.6 0.1 8e-31 106.6 0.1 2.9 4 0 0 4 4 4 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ18443.1 - 1.3e-07 31.9 0.1 4e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ18443.1 - 0.0029 17.7 0.1 0.018 15.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RVT_1 PF00078.27 OAJ18472.1 - 9e-20 71.1 0.0 1.7e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ18472.1 - 2.3e-16 60.1 0.0 5.8e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ18472.1 - 2.7e-12 46.6 0.0 5.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ18472.1 - 4.5e-06 26.6 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 OAJ18472.1 - 0.022 15.4 0.1 0.092 13.4 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease rve_3 PF13683.6 OAJ18472.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Myb_DNA-bind_5 PF13873.6 OAJ18511.1 - 0.034 14.2 0.1 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain FYDLN_acid PF09538.10 OAJ18511.1 - 0.11 13.2 14.4 0.2 12.4 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BUD22 PF09073.10 OAJ18511.1 - 0.24 10.7 13.0 0.33 10.2 13.0 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ18511.1 - 0.55 8.4 10.2 0.66 8.1 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 OAJ18540.1 - 0.028 14.8 4.3 0.055 13.8 4.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 OAJ18540.1 - 1 9.0 3.7 1.8 8.2 3.7 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 OAJ18540.1 - 1.6 8.0 7.4 2.4 7.4 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.29 OAJ18541.1 - 1.3e-33 116.2 0.0 2e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ18541.1 - 3.4e-05 24.1 2.1 0.0059 16.9 0.2 2.8 2 2 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAJ18541.1 - 3.6e-05 23.8 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ18541.1 - 6e-05 23.5 0.3 0.00077 19.9 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 OAJ18541.1 - 0.0016 18.6 0.1 0.0038 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ18541.1 - 0.0016 18.2 0.3 0.011 15.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ18541.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 OAJ18541.1 - 0.036 14.6 1.3 0.1 13.1 0.0 2.2 2 2 0 2 2 2 0 AAA domain Beta_protein PF14350.6 OAJ18541.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta protein RuvB_N PF05496.12 OAJ18541.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 OAJ18541.1 - 0.14 12.5 0.4 0.83 10.0 0.5 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 OAJ18541.1 - 0.14 11.7 4.6 0.15 11.6 1.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ18541.1 - 0.14 12.4 0.4 0.27 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Herpes_UL33 PF03581.13 OAJ18541.1 - 0.16 12.4 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL33-like protein Malate_synthase PF01274.22 OAJ18578.1 - 0.013 13.8 0.2 0.089 11.0 0.1 1.9 1 1 0 2 2 2 0 Malate synthase Tyr-DNA_phospho PF06087.12 OAJ18617.1 - 1.1e-37 129.9 0.0 7.4e-26 91.0 0.0 2.7 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase CX9C PF16860.5 OAJ18618.1 - 4.5e-14 52.2 1.3 5.3e-10 39.1 0.7 2.5 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 OAJ18618.1 - 0.0013 19.0 2.8 0.065 13.6 0.3 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 OAJ18618.1 - 0.022 15.2 0.6 1.7 9.1 0.2 2.2 1 1 1 2 2 2 0 GCK domain Cmc1 PF08583.10 OAJ18618.1 - 0.03 14.3 6.2 1.7 8.7 1.2 3.4 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like YbfN PF13982.6 OAJ18618.1 - 0.034 14.4 0.3 11 6.4 0.0 2.3 2 0 0 2 2 2 0 YbfN-like lipoprotein CHCH PF06747.13 OAJ18618.1 - 0.25 11.5 3.7 13 6.0 0.2 3.3 3 1 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.13 OAJ18618.1 - 0.62 9.8 8.9 5.9 6.7 1.2 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UPF0203 PF05254.12 OAJ18618.1 - 3 8.1 6.7 32 4.9 0.2 3.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0203) TPR_12 PF13424.6 OAJ18642.1 - 2.6e-22 78.9 31.3 4.6e-08 33.2 7.5 7.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ18642.1 - 9.6e-17 60.3 23.9 0.01 15.7 2.1 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ18642.1 - 4.8e-06 26.7 12.5 0.0064 16.6 1.4 3.5 2 1 0 3 3 3 2 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 OAJ18642.1 - 7.6e-06 25.7 15.6 0.73 10.1 0.4 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ18642.1 - 0.00025 20.7 3.6 18 5.4 0.1 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ18642.1 - 0.0036 17.2 16.9 0.97 9.6 0.3 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 OAJ18642.1 - 0.018 15.3 8.1 73 3.9 0.1 6.8 7 0 0 7 7 7 0 PPR repeat DUF2052 PF09747.9 OAJ18642.1 - 0.045 13.9 0.3 0.045 13.9 0.3 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Sipho_Gp157 PF05565.11 OAJ18642.1 - 0.11 12.5 5.1 2.7 8.0 1.1 3.4 1 1 2 3 3 3 0 Siphovirus Gp157 TPR_4 PF07721.14 OAJ18642.1 - 0.25 12.1 10.0 94 4.1 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat RT_RNaseH PF17917.1 OAJ18643.1 - 8.4e-28 96.7 0.0 1.7e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ18643.1 - 2.6e-24 85.1 0.0 5.2e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ18643.1 - 7.7e-14 51.9 0.0 2.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ18643.1 - 1.6e-09 37.7 0.6 3.6e-09 36.6 0.5 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ18643.1 - 0.0073 16.1 0.0 0.0073 16.1 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain DUF2268 PF10026.9 OAJ18643.1 - 0.18 11.3 1.5 0.42 10.2 1.5 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) HTH_Crp_2 PF13545.6 OAJ18644.1 - 0.001 19.0 0.2 0.0092 15.9 0.0 2.6 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.6 OAJ18644.1 - 0.0017 18.1 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 OAJ18644.1 - 0.0028 17.4 0.0 0.0085 15.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain MarR_2 PF12802.7 OAJ18644.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 MarR family MarR PF01047.22 OAJ18644.1 - 0.015 15.2 0.0 0.045 13.7 0.0 1.8 1 0 0 1 1 1 0 MarR family CENP-B_N PF04218.13 OAJ18644.1 - 0.016 14.8 0.0 0.068 12.8 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 OAJ18644.1 - 0.017 15.2 0.1 0.075 13.2 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.21 OAJ18644.1 - 0.076 12.8 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_29 PF13551.6 OAJ18644.1 - 0.11 12.6 0.1 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix HTH_36 PF13730.6 OAJ18644.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_38 PF13936.6 OAJ18644.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 OAJ18644.1 - 0.19 11.3 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Pex14_N PF04695.13 OAJ18683.1 - 4.6 7.9 8.9 1.3 9.7 3.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PPR PF01535.20 OAJ18685.1 - 4.8e-07 29.6 0.0 0.27 11.6 0.0 4.4 4 0 0 4 4 4 3 PPR repeat PPR_2 PF13041.6 OAJ18685.1 - 0.00028 21.0 0.0 0.88 9.8 0.0 4.3 5 0 0 5 5 5 1 PPR repeat family PPR_1 PF12854.7 OAJ18685.1 - 0.0057 16.3 0.5 0.034 13.8 0.1 2.2 2 0 0 2 2 2 1 PPR repeat SURF6 PF04935.12 OAJ18729.1 - 1.3e-32 113.2 50.1 1.3e-32 113.2 50.1 3.2 2 2 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 OAJ18729.1 - 7.9e-15 55.2 2.8 7.9e-15 55.2 2.8 5.2 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 BT1 PF03092.16 OAJ18729.1 - 4.4 5.4 4.6 8.2 4.5 4.6 1.4 1 0 0 1 1 1 0 BT1 family WD40 PF00400.32 OAJ18730.1 - 1.2e-58 193.7 25.6 3.8e-09 37.0 0.0 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ18730.1 - 5.8e-16 58.6 0.9 0.00091 19.5 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ18730.1 - 6.8e-05 22.8 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 OAJ18730.1 - 0.00019 21.0 0.2 0.33 10.7 0.1 3.3 3 0 0 3 3 3 2 Proteasome subunit A N-terminal signature NLE PF08154.12 OAJ18730.1 - 0.00054 20.4 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 OAJ18730.1 - 0.0012 17.9 0.0 0.27 10.2 0.0 3.3 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 OAJ18730.1 - 0.0017 17.2 0.8 1.5 7.5 0.1 4.0 4 1 0 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.6 OAJ18730.1 - 0.0083 15.5 0.8 0.55 9.5 0.0 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 OAJ18730.1 - 0.012 14.3 3.5 23 3.4 0.0 4.3 3 2 1 4 4 4 0 Nucleoporin Nup120/160 IKI3 PF04762.12 OAJ18730.1 - 0.075 11.0 0.1 0.14 10.1 0.1 1.4 1 0 0 1 1 1 0 IKI3 family Beta-lactamase PF00144.24 OAJ18731.1 - 3.5e-37 128.4 0.0 4.8e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase HMG_box_2 PF09011.10 OAJ18732.1 - 0.026 15.1 0.2 0.097 13.3 0.2 2.0 1 0 0 1 1 1 0 HMG-box domain RasGAP PF00616.19 OAJ18765.1 - 0.27 10.9 1.8 0.27 10.9 0.5 1.7 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Trp_syntA PF00290.20 OAJ18766.1 - 7.2e-82 274.1 0.2 1.5e-81 273.1 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 OAJ18766.1 - 3.3e-49 167.9 0.8 6.8e-49 166.8 0.8 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 OAJ18766.1 - 1.3e-05 24.8 0.2 4.7e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein DFP PF04127.15 OAJ18766.1 - 0.04 13.7 0.1 0.66 9.8 0.1 2.4 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PA PF02225.22 OAJ18766.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.8 2 1 0 2 2 2 0 PA domain FAR1 PF03101.15 OAJ18767.1 - 0.58 10.9 4.8 0.31 11.8 2.4 1.8 2 0 0 2 2 2 0 FAR1 DNA-binding domain Arrestin_N PF00339.29 OAJ18801.1 - 1.6e-05 25.0 0.0 4.6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4766 PF15973.5 OAJ18801.1 - 0.027 15.0 1.4 0.027 15.0 1.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4766) PAP_central PF04928.17 OAJ18802.1 - 1.2e-97 325.8 0.0 1.7e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 OAJ18802.1 - 3.9e-50 169.8 0.0 7.9e-50 168.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 OAJ18802.1 - 3e-11 43.4 0.0 7.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ18802.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase YABBY PF04690.13 OAJ18803.1 - 1.9e-08 35.1 0.9 2.2e-08 34.9 0.9 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 OAJ18803.1 - 6.9e-05 23.2 0.5 9e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box MAGI_u5 PF16666.5 OAJ18803.1 - 0.0033 17.6 2.5 0.0037 17.4 2.5 1.2 1 0 0 1 1 1 1 Unstructured region on MAGI Ccdc124 PF06244.12 OAJ18803.1 - 0.0048 17.4 2.3 0.006 17.1 2.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 OAJ18803.1 - 0.0075 16.8 0.3 0.01 16.4 0.3 1.2 1 0 0 1 1 1 1 HMG-box domain RVT_2 PF07727.14 OAJ18847.1 - 2.6e-60 204.1 0.0 3.6e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ18847.1 - 1.9e-20 73.2 0.2 9.4e-20 71.0 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ18847.1 - 8e-07 28.8 0.0 1.1e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ18847.1 - 0.025 14.4 0.0 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ18848.1 - 4.5e-12 45.8 0.1 7.5e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ18848.1 - 1.3e-08 35.0 0.0 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ18848.1 - 0.24 11.5 3.1 0.46 10.6 3.1 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ18848.1 - 4.6 7.2 4.4 8.7 6.3 4.4 1.3 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_8 PF13450.6 OAJ18849.1 - 2.8e-14 53.1 0.0 8.2e-14 51.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ18849.1 - 0.0005 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ18849.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ18849.1 - 0.063 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 OAJ18849.1 - 0.064 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 OAJ18849.1 - 0.073 12.4 0.0 1.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Chorismate_bind PF00425.18 OAJ18893.1 - 1.2e-74 251.1 0.0 3e-74 249.9 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.28 OAJ18893.1 - 9.6e-26 90.7 0.0 2.7e-15 56.6 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 OAJ18893.1 - 1.1e-14 54.8 0.0 3.4e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 OAJ18893.1 - 0.0045 16.8 0.2 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 Sporozoite_P67 PF05642.11 OAJ18894.1 - 0.15 10.1 9.0 0.21 9.6 9.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 OAJ18894.1 - 0.36 10.7 13.4 0.74 9.7 13.4 1.5 1 1 0 1 1 1 0 SPX domain Macoilin PF09726.9 OAJ18894.1 - 0.75 8.3 10.0 1.1 7.8 10.0 1.2 1 0 0 1 1 1 0 Macoilin family Tmemb_cc2 PF10267.9 OAJ18894.1 - 0.85 8.7 6.4 0.22 10.6 3.5 1.4 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Peptidase_S64 PF08192.11 OAJ18894.1 - 1.4 7.3 9.9 2.2 6.7 9.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 FAM199X PF15814.5 OAJ18894.1 - 6.5 5.7 20.3 11 5.0 20.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X AF-4 PF05110.13 OAJ18894.1 - 7.3 4.5 25.9 11 3.9 25.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dabb PF07876.12 OAJ18895.1 - 4.3e-19 68.9 0.0 4.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Pkinase_Tyr PF07714.17 OAJ18932.1 - 1.9e-08 33.9 0.0 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ18932.1 - 1e-06 28.3 0.0 4.4e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain F-box PF00646.33 OAJ18968.1 - 2.5e-05 24.0 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain MFS_1 PF07690.16 OAJ18969.1 - 1.1e-41 143.0 20.7 6.9e-39 133.8 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ18969.1 - 6.6e-08 31.8 19.8 1.9e-06 27.0 19.8 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ18969.1 - 0.00038 19.0 3.7 0.00062 18.3 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.12 OAJ18969.1 - 0.0078 15.9 1.6 0.74 9.5 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF697) DUF3611 PF12263.8 OAJ18969.1 - 6.1 6.7 14.4 0.73 9.7 0.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3611) MCM PF00493.23 OAJ18970.1 - 1.8e-102 341.2 0.3 3.5e-102 340.3 0.3 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ18970.1 - 1.4e-37 128.4 1.0 2.6e-37 127.5 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 OAJ18970.1 - 1.6e-27 95.8 2.6 4.1e-27 94.6 2.6 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 OAJ18970.1 - 8e-26 90.3 2.8 2.1e-25 88.9 0.8 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ18970.1 - 2.3e-21 76.3 1.6 3.9e-21 75.6 0.4 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ18970.1 - 1e-07 31.5 0.0 8.3e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 OAJ18970.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAJ18970.1 - 0.0018 18.1 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ18970.1 - 0.0027 17.7 0.0 0.0078 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Succ_DH_flav_C PF02910.20 OAJ18970.1 - 0.029 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term WD40 PF00400.32 OAJ19016.1 - 3.8e-42 141.4 29.1 2.8e-06 27.9 0.2 12.6 12 3 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ19016.1 - 3.8e-22 78.4 0.3 0.012 15.9 0.0 8.1 5 3 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 OAJ19016.1 - 4.6e-18 65.5 0.6 9.1e-18 64.5 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 OAJ19016.1 - 3.5e-08 32.8 0.6 2.9 6.8 0.0 5.6 4 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ19016.1 - 6.2e-05 21.8 1.0 1.7 7.2 0.0 5.1 6 0 0 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 OAJ19016.1 - 0.00039 19.8 1.3 0.21 10.9 0.0 3.6 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 OAJ19016.1 - 0.0038 16.0 0.0 31 3.2 0.0 4.8 5 0 0 5 5 5 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 OAJ19016.1 - 0.44 9.7 0.0 0.44 9.7 0.0 4.4 4 2 2 6 6 6 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Sporozoite_P67 PF05642.11 OAJ19016.1 - 0.48 8.4 7.3 0.23 9.5 3.7 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 OAJ19016.1 - 1.2 7.1 4.6 1.7 6.7 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OAJ19016.1 - 2.7 8.0 5.8 6.6 6.7 5.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal AIF_C PF14721.6 OAJ19016.1 - 6.2 7.2 5.5 3.5 8.0 2.2 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CS PF04969.16 OAJ19017.1 - 5.8e-08 33.6 0.0 8.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 CS domain Serglycin PF04360.12 OAJ19018.1 - 0.0022 17.9 2.1 0.0022 17.9 2.1 2.7 2 0 0 2 2 2 1 Serglycin A_deaminase PF00962.22 OAJ19062.1 - 2.6e-26 92.7 0.0 4.6e-26 91.9 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 OAJ19062.1 - 2.3e-05 24.6 0.0 4.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal NOB1_Zn_bind PF08772.11 OAJ19063.1 - 2.3e-30 104.6 1.2 4.3e-30 103.7 1.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 OAJ19063.1 - 5.5e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 PIN domain of ribonuclease Nudix_N_2 PF14803.6 OAJ19063.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 Nudix N-terminal zf-NADH-PPase PF09297.11 OAJ19063.1 - 2.1 8.1 5.1 1.3 8.8 0.4 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rad21_Rec8_N PF04825.13 OAJ19064.1 - 1.1e-38 131.8 0.0 2e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ19064.1 - 5.7e-15 54.3 1.3 8.8e-15 53.7 0.1 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 OAJ19064.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Zn_clus PF00172.18 OAJ19128.1 - 3.4e-08 33.5 8.3 5.4e-08 32.8 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ19128.1 - 9.6e-06 24.8 0.3 3.3e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fmp27_SW PF10305.9 OAJ19128.1 - 0.12 13.1 2.2 0.55 11.0 1.4 2.5 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain HD_3 PF13023.6 OAJ19129.1 - 4.4e-40 137.3 0.0 7.5e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 OAJ19129.1 - 6.4e-07 29.3 0.4 1.4e-06 28.2 0.4 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 OAJ19129.1 - 0.00099 19.3 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 HD domain Antirestrict PF03230.13 OAJ19129.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Antirestriction protein adh_short PF00106.25 OAJ19171.1 - 6.4e-29 100.8 0.0 8.9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ19171.1 - 2.2e-16 60.1 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ19171.1 - 2.9e-08 33.9 0.8 8.5e-08 32.3 0.8 1.7 1 1 0 1 1 1 1 KR domain DUF5546 PF17700.1 OAJ19171.1 - 0.061 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5546) HMG_box PF00505.19 OAJ19172.1 - 5.9e-17 61.9 22.2 3.9e-09 36.8 1.1 3.7 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ19172.1 - 2.2e-14 53.8 15.7 5.3e-09 36.5 0.5 2.8 3 0 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 OAJ19172.1 - 0.091 12.7 0.5 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Proton_antipo_N PF00662.20 OAJ19173.1 - 0.092 12.8 0.4 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Sec1 PF00995.23 OAJ19209.1 - 0.047 12.9 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Sec1 family Herpes_capsid PF06112.11 OAJ19210.1 - 0.054 13.6 0.0 0.059 13.4 0.0 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MgtE PF01769.16 OAJ19253.1 - 0.0064 16.9 4.7 0.065 13.6 0.5 2.6 2 0 0 2 2 2 2 Divalent cation transporter HemX PF04375.14 OAJ19253.1 - 0.52 9.5 7.9 0.31 10.3 5.7 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FAD_binding_6 PF00970.24 OAJ19254.1 - 3.8e-06 27.2 0.0 2.4e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ19254.1 - 4.4e-05 24.1 0.0 0.031 14.9 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain DAGK_cat PF00781.24 OAJ19254.1 - 0.13 11.9 0.1 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DUF1206 PF06724.11 OAJ19254.1 - 0.2 11.8 2.9 0.32 11.1 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) RVT_2 PF07727.14 OAJ19303.1 - 3.6e-59 200.3 0.0 5.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ19303.1 - 4.1e-16 59.3 0.0 1.7e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ19303.1 - 2.1e-11 43.6 0.0 4.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ19303.1 - 1.4e-05 24.6 0.1 4.3e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 OAJ19303.1 - 0.0022 17.7 0.2 0.0057 16.4 0.2 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_3 PF13456.6 OAJ19303.1 - 0.0069 16.2 0.6 0.082 12.7 0.1 2.9 3 0 0 3 3 3 1 Reverse transcriptase-like gag_pre-integrs PF13976.6 OAJ19303.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain GntR PF00392.21 OAJ19303.1 - 0.087 12.5 0.2 2.2 8.0 0.2 2.6 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-CCHC PF00098.23 OAJ19303.1 - 0.26 11.4 7.4 0.77 10.0 7.4 1.9 1 0 0 1 1 1 0 Zinc knuckle MKT1_C PF12246.8 OAJ19304.1 - 1.1e-75 254.0 0.0 1.9e-74 249.9 0.0 2.4 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 OAJ19304.1 - 6.9e-23 80.8 0.0 1.6e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 OAJ19304.1 - 6.7e-08 32.9 0.0 1.9e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Spt20 PF12090.8 OAJ19304.1 - 1.5 8.4 10.9 31 4.1 9.9 2.5 2 0 0 2 2 2 0 Spt20 family PB1 PF00564.24 OAJ19305.1 - 4.8e-05 23.2 0.3 9.1e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 PB1 domain CBS PF00571.28 OAJ19305.1 - 0.052 14.0 0.8 0.12 12.8 0.1 1.9 2 0 0 2 2 2 0 CBS domain SelP_N PF04592.14 OAJ19305.1 - 0.12 11.7 8.2 0.17 11.2 8.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2340 PF10209.9 OAJ19352.1 - 1.4e-46 157.9 0.0 1.8e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) RRP7 PF12923.7 OAJ19353.1 - 7.2e-23 81.0 0.3 7.2e-23 81.0 0.3 2.3 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 OAJ19353.1 - 2.7e-13 50.0 1.6 2.9e-12 46.7 1.6 2.1 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 OAJ19353.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH_9 PF15410.6 OAJ19354.1 - 1.8e-29 102.5 0.0 3.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 OAJ19354.1 - 4.3e-28 98.2 0.1 9.2e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 OAJ19354.1 - 0.00027 21.4 0.0 0.00071 20.1 0.0 1.7 1 1 0 1 1 1 1 PH domain PhyH PF05721.13 OAJ19355.1 - 1.7e-41 142.8 0.0 3e-41 142.0 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pkinase PF00069.25 OAJ19398.1 - 7e-67 225.6 0.0 8.6e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ19398.1 - 3.1e-31 108.6 0.0 4e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ19398.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ19398.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ19398.1 - 0.0022 17.4 0.1 0.005 16.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ19398.1 - 0.013 14.9 0.0 0.14 11.4 0.0 2.0 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 OAJ19398.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAJ19398.1 - 0.045 13.4 0.1 0.093 12.3 0.0 1.5 2 0 0 2 2 2 0 RIO1 family DEAD PF00270.29 OAJ19400.1 - 8.3e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ19400.1 - 0.0035 17.4 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rRNA_proc-arch PF13234.6 OAJ19401.1 - 7.7e-24 85.1 0.3 1.1e-23 84.6 0.3 1.2 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 OAJ19401.1 - 1e-15 57.7 1.3 1.8e-15 57.0 0.2 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain H_lectin PF09458.10 OAJ19441.1 - 7.6e-16 58.1 0.0 3.5e-07 30.3 0.0 3.4 3 1 0 3 3 3 2 H-type lectin domain HAD_2 PF13419.6 OAJ19485.1 - 0.061 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ19485.1 - 0.087 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like COX6B PF02297.17 OAJ19485.1 - 0.1 12.8 0.1 0.25 11.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF2373 PF10180.9 OAJ19486.1 - 2.1e-13 49.9 0.1 7e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.18 OAJ19486.1 - 0.17 12.0 0.3 0.37 10.9 0.3 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family DNA_pol_phi PF04931.13 OAJ19486.1 - 1.1 7.3 7.0 1.9 6.5 7.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pro_isomerase PF00160.21 OAJ19487.1 - 2.2e-42 145.0 0.0 4.3e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 OAJ19487.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2406 PF10295.9 OAJ19487.1 - 0.4 11.4 2.0 12 6.7 0.2 2.9 1 1 1 2 2 2 0 Uncharacterised protein (DUF2406) Rtf2 PF04641.12 OAJ19487.1 - 0.41 10.0 6.1 0.17 11.2 0.1 2.9 3 1 0 3 3 3 0 Rtf2 RING-finger DUF1295 PF06966.12 OAJ19488.1 - 5.7e-35 120.9 0.1 3.9e-34 118.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DnaJ PF00226.31 OAJ19528.1 - 1.7e-15 56.9 0.1 3.5e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain SUIM_assoc PF16619.5 OAJ19528.1 - 0.00041 20.4 0.0 0.098 12.7 0.0 2.8 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 PDGLE PF13190.6 OAJ19529.1 - 0.073 13.0 1.7 3.1 7.8 0.4 2.5 2 1 0 2 2 2 0 PDGLE domain Gly_reductase PF09338.11 OAJ19529.1 - 0.21 9.9 2.0 5 5.4 0.0 2.0 2 0 0 2 2 2 0 Glycine/sarcosine/betaine reductase component B subunits SCHIP-1 PF10148.9 OAJ19529.1 - 0.64 9.6 1.5 0.85 9.2 1.5 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Mucin PF01456.17 OAJ19530.1 - 0.00015 21.7 25.5 0.00015 21.7 25.5 3.3 3 0 0 3 3 3 1 Mucin-like glycoprotein MGC-24 PF05283.11 OAJ19530.1 - 0.0042 17.5 8.2 0.0042 17.5 8.2 3.4 4 0 0 4 4 4 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF2207 PF09972.9 OAJ19530.1 - 0.069 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tyosinase_C PF18132.1 OAJ19576.1 - 0.052 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Tyosinase C-terminal domain ApbA_C PF08546.11 OAJ19577.1 - 3.4e-24 85.4 0.0 1.3e-23 83.5 0.0 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ19577.1 - 5.5e-20 71.6 0.0 8.3e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 OAJ19577.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 OAJ19577.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ19577.1 - 0.058 13.7 0.2 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 OAJ19577.1 - 0.087 12.4 0.3 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DAO PF01266.24 OAJ19577.1 - 0.13 11.8 0.2 0.27 10.8 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 OAJ19577.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LIFR_N PF18207.1 OAJ19577.1 - 0.21 12.0 0.1 0.5 10.8 0.1 1.6 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Methyltransf_11 PF08241.12 OAJ19578.1 - 6.5e-08 33.1 0.1 5.3e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ19578.1 - 1.1e-07 32.4 0.0 3.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ19578.1 - 4.1e-07 30.0 0.0 6.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ19578.1 - 1.2e-06 29.1 0.1 1.3e-05 25.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ19578.1 - 0.0011 20.0 0.1 0.02 15.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 OAJ19578.1 - 0.014 15.1 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 OAJ19578.1 - 0.015 15.1 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ19578.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RisS_PPD PF16524.5 OAJ19578.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Swi6_N PF18530.1 OAJ19578.1 - 0.14 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Swi6 N-terminal domain MFS_1 PF07690.16 OAJ19580.1 - 1.5e-28 99.7 13.1 1.5e-28 99.7 13.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 OAJ19580.1 - 5.4e-07 29.2 3.8 1.9e-06 27.5 1.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 OAJ19580.1 - 8.2e-07 28.2 4.6 2.6e-06 26.6 4.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ19580.1 - 0.0054 15.2 0.9 0.0083 14.6 0.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 OAJ19580.1 - 0.0076 15.1 0.0 0.018 13.9 0.0 1.9 1 1 0 1 1 1 1 MFS_1 like family Profilin PF00235.19 OAJ19628.1 - 5.2e-46 156.0 0.0 5.8e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Profilin DASH_Dad2 PF08654.10 OAJ19629.1 - 1.5e-21 76.6 0.0 2.8e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 DUF5320 PF17253.2 OAJ19629.1 - 0.37 11.9 4.1 1.6 9.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) NDUFA12 PF05071.16 OAJ19630.1 - 1.7e-30 105.7 0.2 2.3e-30 105.3 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PTH2 PF01981.16 OAJ19631.1 - 5.3e-47 158.9 1.2 6.8e-47 158.6 1.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_11 PF13414.6 OAJ19631.1 - 0.022 14.4 0.1 0.052 13.2 0.1 1.7 1 0 0 1 1 1 0 TPR repeat Nuc_deoxyrib_tr PF05014.15 OAJ19631.1 - 0.047 13.7 0.2 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Asp_protease PF09668.10 OAJ19632.1 - 1.7e-58 195.8 0.0 2.4e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ19632.1 - 4.3e-21 75.3 0.0 1.2e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ19632.1 - 5.4e-10 39.8 0.0 1.8e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 OAJ19632.1 - 2.3e-09 36.8 0.0 4.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ19632.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ19632.1 - 0.0062 17.0 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain RVP PF00077.20 OAJ19632.1 - 0.01 16.1 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 OAJ19632.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RabGAP-TBC PF00566.18 OAJ19633.1 - 1.2e-45 155.8 0.1 3.1e-45 154.5 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SNF2_N PF00176.23 OAJ19678.1 - 5.6e-55 186.5 0.1 8.7e-55 185.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ19678.1 - 9.5e-15 54.9 0.0 2.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ19678.1 - 9.8e-10 38.7 0.0 2.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ19678.1 - 1.9e-06 27.3 0.0 3.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 OAJ19678.1 - 3.3e-06 27.0 0.3 9.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ19678.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 OAJ19678.1 - 0.0098 14.8 0.0 0.045 12.6 0.0 2.0 2 1 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Calcipressin PF04847.12 OAJ19678.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Calcipressin TusA PF01206.17 OAJ19678.1 - 0.096 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Sulfurtransferase TusA TPR_1 PF00515.28 OAJ19679.1 - 2.2e-28 96.9 10.9 1.9e-05 24.2 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ19679.1 - 8.7e-26 87.9 15.0 5e-05 23.2 0.0 9.6 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ19679.1 - 2.1e-25 86.7 16.5 2.5e-05 24.1 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC8 PF04049.13 OAJ19679.1 - 6.2e-17 62.0 1.2 3e-16 59.8 1.2 2.1 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 OAJ19679.1 - 5.3e-15 54.8 26.3 0.00021 21.8 0.1 9.1 7 4 3 10 10 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ19679.1 - 1.3e-13 50.3 6.1 0.023 15.1 0.0 7.3 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ19679.1 - 3.6e-13 48.9 1.1 0.00041 20.0 0.0 4.8 5 0 0 5 5 5 3 TPR repeat ANAPC3 PF12895.7 OAJ19679.1 - 1.8e-11 44.1 9.5 0.00014 22.0 0.3 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 OAJ19679.1 - 5.6e-10 39.6 7.9 0.5 10.9 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ19679.1 - 1.2e-09 38.6 16.6 0.00054 20.5 0.0 6.8 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ19679.1 - 2.3e-09 37.4 15.0 0.00057 20.1 1.3 7.4 6 4 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ19679.1 - 9.4e-09 34.7 10.8 0.00035 20.4 0.1 5.8 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ19679.1 - 9.2e-08 32.1 3.0 0.68 10.1 0.0 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ19679.1 - 1.6e-06 27.6 4.0 0.13 11.4 0.0 4.9 1 1 3 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.10 OAJ19679.1 - 9.3e-05 21.6 0.0 0.045 12.8 0.0 3.0 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 OAJ19679.1 - 0.00018 22.0 17.7 7.3 7.5 0.0 9.3 10 1 1 11 11 10 1 Tetratricopeptide repeat PPR PF01535.20 OAJ19679.1 - 0.067 13.5 0.9 17 6.0 0.0 4.0 5 0 0 5 5 4 0 PPR repeat TPR_10 PF13374.6 OAJ19679.1 - 0.11 12.4 18.1 0.27 11.2 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat RPN7 PF10602.9 OAJ19679.1 - 0.11 12.2 0.2 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 SNAP PF14938.6 OAJ19679.1 - 0.23 10.9 4.2 1.3 8.4 0.1 3.2 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP PMI_typeI PF01238.21 OAJ19720.1 - 6.9e-110 367.8 0.0 2.2e-109 366.1 0.0 1.7 1 1 0 1 1 1 1 Phosphomannose isomerase type I POB3_N PF17292.2 OAJ19721.1 - 1.5e-23 83.1 0.0 1e-20 74.0 0.0 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 OAJ19721.1 - 6.3e-20 70.9 0.0 1.6e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 OAJ19721.1 - 1.9e-19 69.8 0.1 4.7e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M41 PF01434.18 OAJ19760.1 - 6.4e-62 208.8 0.2 6.4e-62 208.8 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 OAJ19760.1 - 3.3e-42 144.0 0.0 8.4e-42 142.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ19760.1 - 3.6e-11 42.7 0.1 9.4e-11 41.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 OAJ19760.1 - 2.5e-10 40.7 1.2 4.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_22 PF13401.6 OAJ19760.1 - 0.0025 18.1 0.1 0.49 10.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 OAJ19760.1 - 0.0052 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 OAJ19760.1 - 0.006 17.0 0.0 0.2 12.0 0.1 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ19760.1 - 0.015 15.3 0.1 0.11 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ19760.1 - 0.028 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 OAJ19760.1 - 0.032 14.0 0.0 0.076 12.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OAJ19760.1 - 0.093 12.3 0.5 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Apt1 PF10351.9 OAJ19760.1 - 3.8 6.2 8.6 5.6 5.7 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Collagen PF01391.18 OAJ19761.1 - 6.3e-24 83.5 152.3 5.4e-07 29.3 26.2 5.4 1 1 3 4 4 4 3 Collagen triple helix repeat (20 copies) ARID PF01388.21 OAJ19762.1 - 8.2e-05 23.2 2.8 0.014 16.1 0.0 3.3 4 0 0 4 4 4 2 ARID/BRIGHT DNA binding domain DUF966 PF06136.13 OAJ19762.1 - 0.067 12.9 17.5 0.79 9.4 8.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Zip PF02535.22 OAJ19762.1 - 0.16 11.1 11.9 0.71 9.0 0.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter MMR1 PF08505.10 OAJ19762.1 - 2.7 8.2 28.4 4.1 7.6 5.4 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.11 OAJ19762.1 - 9.2 5.6 15.9 0.23 10.9 6.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF4781 PF16013.5 OAJ19806.1 - 0.014 14.2 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Ail_Lom PF06316.11 OAJ19806.1 - 0.04 13.6 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Alpha_GJ PF03229.13 OAJ19806.1 - 0.067 13.7 2.5 14 6.3 0.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J KDZ PF18758.1 OAJ19808.1 - 6.3e-48 163.3 0.0 9.3e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Histone PF00125.24 OAJ19809.1 - 2.3e-43 147.7 0.7 2.6e-43 147.5 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ19809.1 - 1.4e-05 25.4 0.1 2.6e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 OAJ19809.1 - 0.00072 19.7 1.0 0.00089 19.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ19809.1 - 0.01 16.1 0.4 0.38 11.1 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Benyvirus_P25 PF05744.11 OAJ19811.1 - 0.06 12.6 0.1 0.063 12.6 0.1 1.0 1 0 0 1 1 1 0 Benyvirus P25/P26 protein p450 PF00067.22 OAJ19858.1 - 3e-49 168.0 0.0 4e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3071 PF11268.8 OAJ19858.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) DDE_1 PF03184.19 OAJ19859.1 - 1.5e-20 73.6 0.0 4.9e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ19859.1 - 1.3e-10 41.1 0.1 9.1e-10 38.4 0.0 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ19859.1 - 0.003 17.3 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Rpn3_C PF08375.11 OAJ19859.1 - 1.4 9.4 3.7 8.2 6.9 3.7 2.4 1 1 0 1 1 1 0 Proteasome regulatory subunit C-terminal Spt20 PF12090.8 OAJ19860.1 - 0.027 14.1 11.8 0.034 13.8 11.8 1.1 1 0 0 1 1 1 0 Spt20 family EBP50_C PF09007.11 OAJ19860.1 - 0.13 13.2 8.2 13 6.7 7.0 2.2 2 0 0 2 2 2 0 EBP50, C-terminal DUF3408 PF11888.8 OAJ19860.1 - 0.26 11.4 4.5 0.38 10.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Endostatin PF06482.11 OAJ19860.1 - 1.1 8.7 9.1 1 8.7 7.9 1.5 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Presenilin PF01080.17 OAJ19860.1 - 1.5 7.5 7.1 1.9 7.1 7.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 OAJ19860.1 - 1.7 8.8 6.6 2.4 8.4 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CENP-U PF13097.6 OAJ19860.1 - 3.2 7.7 10.6 4.4 7.2 10.6 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Pex14_N PF04695.13 OAJ19860.1 - 9.9 6.8 14.9 2.9 8.5 11.9 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 OAJ19860.1 - 9.9 7.2 6.6 18 6.4 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) p450 PF00067.22 OAJ19861.1 - 2e-52 178.5 0.0 2.4e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHRD PF07452.12 OAJ19903.1 - 1.3e-29 103.5 2.7 1.3e-13 51.9 0.2 2.2 2 0 0 2 2 2 2 CHRD domain PWWP PF00855.17 OAJ19904.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.0 1 0 0 1 1 1 0 PWWP domain Acetyltransf_3 PF13302.7 OAJ19906.1 - 5.8e-10 40.0 0.0 6.7e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tugs PF17840.1 OAJ19906.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain ADH_zinc_N PF00107.26 OAJ19945.1 - 1.1e-32 112.8 0.4 2e-32 111.9 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ19945.1 - 9.5e-15 55.8 0.0 1.6e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ19945.1 - 8.8e-05 22.4 0.0 0.0003 20.6 0.0 1.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 OAJ19945.1 - 0.0017 17.7 0.3 0.0031 16.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 OAJ19945.1 - 0.046 13.2 0.2 0.086 12.3 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase HupF_HypC PF01455.18 OAJ19945.1 - 0.14 12.4 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 HupF/HypC family Ribosomal_L4 PF00573.22 OAJ19946.1 - 3.7e-61 206.2 0.0 6e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Thioredoxin_3 PF13192.6 OAJ19946.1 - 0.096 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain DUF3591 PF12157.8 OAJ19947.1 - 7.7e-171 568.6 0.1 9.9e-171 568.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 OAJ19947.1 - 1.4e-05 24.8 3.7 3.7e-05 23.5 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ19947.1 - 0.035 14.2 1.6 0.058 13.5 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Mtf2_C PF14061.6 OAJ19991.1 - 0.049 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 UPF0181 PF03701.14 OAJ19993.1 - 0.0092 15.6 1.4 0.012 15.3 0.3 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0181) MatP_C PF17414.2 OAJ19993.1 - 0.082 13.1 0.3 0.29 11.3 0.3 1.9 1 1 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain RVT_1 PF00078.27 OAJ20033.1 - 2.5e-19 69.7 0.0 4.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ20033.1 - 0.019 14.5 4.0 0.053 13.0 4.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cellulase PF00150.18 OAJ20079.1 - 1.2e-13 51.2 0.5 1.8e-13 50.6 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_17 PF13431.6 OAJ20080.1 - 1e-08 34.9 0.9 0.0087 16.4 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ20080.1 - 2.7e-08 34.3 21.7 0.0028 18.3 1.6 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ20080.1 - 3.1e-07 30.0 7.1 0.13 12.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ20080.1 - 3.2e-07 30.0 0.5 0.09 13.0 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ20080.1 - 1.1e-05 25.6 1.9 0.0033 17.6 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 OAJ20080.1 - 1.2e-05 25.7 22.6 0.037 14.9 0.7 7.8 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ20080.1 - 0.00031 20.4 1.9 2.3 8.2 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ20080.1 - 0.0088 16.5 16.3 0.071 13.6 0.3 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ20080.1 - 0.021 14.5 0.8 4.9 6.9 0.1 4.0 3 1 1 4 4 4 0 TPR repeat ChAPs PF09295.10 OAJ20080.1 - 0.83 8.6 5.6 1.4 7.8 0.5 2.5 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 OAJ20080.1 - 1.3 9.2 22.2 1.7 8.9 0.8 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ20080.1 - 9.1 6.6 7.4 22 5.4 0.0 4.3 6 0 0 6 6 4 0 Tetratricopeptide repeat RNase_P_Rpp14 PF01900.19 OAJ20081.1 - 1.6e-25 89.3 0.0 2.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF4750 PF15938.5 OAJ20123.1 - 0.012 15.2 0.9 0.012 15.2 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4750) TrbC PF04956.13 OAJ20123.1 - 3.1 8.1 14.9 0.5 10.6 0.2 4.4 4 0 0 4 4 4 0 TrbC/VIRB2 family CLP1_P PF16575.5 OAJ20124.1 - 1.5e-24 86.9 0.0 4.7e-16 59.1 0.0 2.4 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 OAJ20124.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 OAJ20124.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 OAJ20124.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 OAJ20124.1 - 0.22 11.6 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SH3_1 PF00018.28 OAJ20125.1 - 4.5e-13 48.6 0.1 7.2e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ20125.1 - 7.6e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ20125.1 - 2.2e-07 30.4 0.0 4.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 OAJ20125.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SusE PF14292.6 OAJ20125.1 - 0.023 14.9 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 SusE outer membrane protein SH3_3 PF08239.11 OAJ20125.1 - 0.033 14.5 0.2 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Bacterial SH3 domain Rib_5-P_isom_A PF06026.14 OAJ20170.1 - 1.9e-60 203.4 0.0 3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 OAJ20170.1 - 0.052 13.5 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain GREB1 PF15782.5 OAJ20171.1 - 8 3.4 7.0 9.2 3.2 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cellulase PF00150.18 OAJ20172.1 - 8.2e-12 45.1 0.1 1.8e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Myb_DNA-bind_3 PF12776.7 OAJ20210.1 - 6.6e-18 65.5 2.9 1.2e-17 64.6 2.9 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ20210.1 - 2.5e-06 27.8 5.5 5.4e-06 26.7 5.5 1.6 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ20210.1 - 0.0049 17.0 0.7 0.012 15.8 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ20210.1 - 0.024 14.9 1.8 0.024 14.9 1.8 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain CENP-B_dimeris PF09026.10 OAJ20210.1 - 0.078 13.4 5.4 0.17 12.3 5.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SOG2 PF10428.9 OAJ20210.1 - 0.17 11.1 0.1 0.34 10.1 0.1 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Myb_DNA-bind_5 PF13873.6 OAJ20210.1 - 0.72 10.0 8.2 0.14 12.2 2.8 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain G-alpha PF00503.20 OAJ20211.1 - 2.6e-123 411.7 1.3 3e-123 411.5 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ20211.1 - 8.9e-17 61.1 0.5 9.6e-12 44.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ20211.1 - 2.3e-05 23.9 0.3 0.0047 16.3 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ20211.1 - 0.00069 19.8 0.1 1.9 8.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 OAJ20211.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 CHC2 zinc finger MCM PF00493.23 OAJ20211.1 - 0.0078 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MMR_HSR1 PF01926.23 OAJ20211.1 - 0.022 14.9 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ20211.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.4 2 1 1 3 3 3 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ20211.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arm PF00514.23 OAJ20212.1 - 1.2e-74 244.3 10.4 3e-12 46.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ20212.1 - 5.2e-21 74.7 5.8 2e-07 31.3 0.0 5.6 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 OAJ20212.1 - 4.1e-18 64.7 0.0 2e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 OAJ20212.1 - 4.9e-16 58.9 6.2 1.1e-06 28.9 0.2 5.5 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 OAJ20212.1 - 1.5e-15 56.0 5.3 0.00047 20.2 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat IBB PF01749.20 OAJ20212.1 - 7.7e-15 55.1 1.9 1.5e-14 54.1 1.3 1.8 2 0 0 2 2 2 1 Importin beta binding domain RICTOR_V PF14668.6 OAJ20212.1 - 3.3e-06 27.2 1.2 0.091 13.0 0.1 4.1 2 2 2 4 4 4 3 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 OAJ20212.1 - 0.0056 15.3 0.0 0.014 14.0 0.0 1.6 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.16 OAJ20212.1 - 0.018 15.7 4.3 2.6 9.0 0.0 4.9 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat CTNNBL PF08216.11 OAJ20212.1 - 0.17 12.1 0.6 7.5 6.8 0.0 3.6 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear UTP15_C PF09384.10 OAJ20253.1 - 7.1e-35 119.8 0.0 1.4e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 OAJ20253.1 - 4e-23 81.2 0.8 4.7e-06 27.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 OAJ20253.1 - 0.0088 15.0 0.0 3.1 6.7 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MutL PF13941.6 OAJ20253.1 - 0.08 11.5 1.7 0.12 11.0 1.7 1.1 1 0 0 1 1 1 0 MutL protein Nup160 PF11715.8 OAJ20253.1 - 0.088 11.4 0.3 0.79 8.3 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 LIDHydrolase PF10230.9 OAJ20255.1 - 6.8e-46 157.0 0.0 2.7e-45 155.0 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 OAJ20255.1 - 4.6e-06 27.4 2.4 6.2e-06 27.0 1.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ20255.1 - 4.3e-05 22.9 0.1 9.5e-05 21.8 0.1 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 OAJ20255.1 - 0.024 14.5 0.1 0.12 12.2 0.1 2.1 3 0 0 3 3 3 0 Serine hydrolase Abhydrolase_3 PF07859.13 OAJ20255.1 - 0.033 14.0 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 OAJ20255.1 - 0.04 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MULE PF10551.9 OAJ20301.1 - 3.5e-17 62.6 0.0 8.6e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ20301.1 - 2.3e-10 39.9 0.0 3.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family FAR1 PF03101.15 OAJ20301.1 - 0.00066 20.3 0.4 0.0019 18.9 0.4 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain SWIM PF04434.17 OAJ20301.1 - 0.0016 18.1 0.1 0.0037 16.9 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_ISL3 PF01610.17 OAJ20301.1 - 0.0064 16.2 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE_Tnp_IS240 PF13610.6 OAJ20301.1 - 0.018 15.3 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 DDE domain Myc_N PF01056.18 OAJ20301.1 - 0.033 14.1 0.4 0.081 12.8 0.4 1.6 1 0 0 1 1 1 0 Myc amino-terminal region rve PF00665.26 OAJ20301.1 - 0.056 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain PP2C PF00481.21 OAJ20344.1 - 7.4e-29 101.2 0.2 1.4e-27 97.0 0.0 2.7 3 0 0 3 3 3 1 Protein phosphatase 2C SKA1 PF07160.12 OAJ20344.1 - 2.5 7.9 7.9 6.1 6.6 7.9 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FAM60A PF15396.6 OAJ20344.1 - 3.4 7.6 4.7 4.7 7.2 3.5 1.8 2 0 0 2 2 2 0 Protein Family FAM60A zf-RING_2 PF13639.6 OAJ20345.1 - 2.1e-12 47.2 4.3 4.8e-12 46.0 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 OAJ20345.1 - 1.4e-10 40.7 2.1 1.4e-10 40.7 2.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 OAJ20345.1 - 1.3e-06 28.1 3.7 2.5e-06 27.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 OAJ20345.1 - 2.4e-05 24.3 0.1 0.00029 20.8 0.0 2.5 2 0 0 2 2 2 1 PA domain zf-C3HC4 PF00097.25 OAJ20345.1 - 3e-05 23.8 1.7 6.1e-05 22.8 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ20345.1 - 3e-05 23.9 2.0 5.6e-05 23.0 2.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ20345.1 - 0.00038 20.4 0.3 0.00038 20.4 0.3 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 OAJ20345.1 - 0.00064 20.0 4.7 0.0025 18.1 4.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 OAJ20345.1 - 0.0012 18.7 5.4 0.0027 17.5 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ20345.1 - 0.04 14.0 1.9 0.1 12.7 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 OAJ20345.1 - 0.099 12.9 1.3 0.2 11.9 1.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family Baculo_RING PF05883.11 OAJ20345.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.6 OAJ20345.1 - 0.44 10.4 5.6 1 9.2 5.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 OAJ20345.1 - 2.8 8.2 4.5 12 6.2 4.4 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain DUF1639 PF07797.14 OAJ20394.1 - 0.077 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) rve PF00665.26 OAJ20395.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ20395.1 - 4.3e-16 58.7 0.0 8.3e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 OAJ20395.1 - 5.2e-07 29.5 0.0 8.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.17 OAJ20396.1 - 5.4e-09 36.2 0.1 4.5e-08 33.3 0.1 2.2 1 1 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.27 OAJ20397.1 - 7.8e-32 110.6 0.0 6.8e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ20397.1 - 1.4e-31 108.5 0.0 2.8e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ20397.1 - 1.2e-25 89.8 0.0 2.1e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase YL1 PF05764.13 OAJ20442.1 - 0.00017 21.8 16.6 0.00028 21.1 16.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein DNA_pol_phi PF04931.13 OAJ20442.1 - 0.97 7.5 25.2 1.4 6.9 25.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ20442.1 - 1 7.5 19.7 1.7 6.7 19.7 1.3 1 0 0 1 1 1 0 Nop14-like family KDZ PF18758.1 OAJ20444.1 - 1.3e-35 123.1 0.0 1.9e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 OAJ20444.1 - 6.6e-07 29.5 0.1 2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 OAJ20444.1 - 9.7e-05 22.5 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases COesterase PF00135.28 OAJ20492.1 - 9.2e-95 318.4 0.1 1.6e-94 317.7 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ20492.1 - 2e-06 27.8 2.1 0.00086 19.2 0.1 2.9 3 1 0 3 3 3 2 alpha/beta hydrolase fold RraA-like PF03737.15 OAJ20493.1 - 7.1e-36 123.6 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA DnaJ_C PF01556.18 OAJ20493.1 - 1.4e-32 112.8 0.0 2.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ20493.1 - 1.7e-23 82.5 0.5 3.1e-23 81.6 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ20493.1 - 7.2e-13 48.7 18.7 1.3e-12 47.9 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF3484 PF11983.8 OAJ20493.1 - 0.9 10.7 6.0 2.5 9.3 6.0 1.7 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Anti-TRAP PF15777.5 OAJ20493.1 - 1.1 9.2 14.8 0.48 10.4 4.1 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein NatB_MDM20 PF09797.9 OAJ20494.1 - 3.5e-57 194.1 0.1 8.3e-57 192.8 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Med11 PF10280.9 OAJ20494.1 - 0.034 14.6 0.3 0.58 10.6 0.0 2.9 3 0 0 3 3 3 0 Mediator complex protein Exo_endo_phos PF03372.23 OAJ20544.1 - 9.9e-12 44.9 0.0 6.9e-11 42.1 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RPN2_C PF18004.1 OAJ20544.1 - 0.17 11.8 1.4 0.3 11.0 1.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1561 PF07598.11 OAJ20544.1 - 0.31 9.2 0.0 0.51 8.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) DUF4746 PF15928.5 OAJ20544.1 - 0.65 9.4 5.0 0.91 8.9 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sfi1 PF08457.10 OAJ20545.1 - 6.9e-16 57.9 92.5 6.5e-05 21.7 8.1 6.5 1 1 3 4 4 4 4 Sfi1 spindle body protein Arm PF00514.23 OAJ20546.1 - 0.00038 20.4 4.6 0.035 14.2 0.1 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DNA_pol_E_B PF04042.16 OAJ20596.1 - 7.7e-30 103.8 0.5 1.1e-29 103.3 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 OAJ20596.1 - 5.4e-18 65.9 0.0 1e-17 64.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal GMC_oxred_N PF00732.19 OAJ20597.1 - 3.5e-51 174.4 1.1 1e-49 169.5 1.1 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ20597.1 - 5.8e-29 101.5 0.0 1.1e-28 100.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ20597.1 - 2.3e-06 27.0 0.1 9.9e-05 21.6 0.0 2.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ20597.1 - 8.5e-06 25.1 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 OAJ20597.1 - 1.2e-05 25.5 0.1 3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ20597.1 - 0.001 18.4 0.0 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ20597.1 - 0.0053 16.4 0.3 0.0053 16.4 0.3 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ20597.1 - 0.0069 15.7 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 OAJ20597.1 - 0.01 15.1 0.1 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 OAJ20597.1 - 0.035 12.8 0.1 0.083 11.6 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 OAJ20597.1 - 0.042 14.1 0.2 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 OAJ20597.1 - 0.05 12.8 1.2 0.19 11.0 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ20597.1 - 0.094 12.7 0.3 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Myb_DNA-bind_3 PF12776.7 OAJ20598.1 - 2.3e-15 57.4 0.5 3.5e-15 56.7 0.5 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HHH_8 PF14716.6 OAJ20598.1 - 0.0064 16.8 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain Myb_DNA-bind_4 PF13837.6 OAJ20598.1 - 0.027 14.8 0.2 0.027 14.8 0.2 1.7 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pox_A28 PF04584.14 OAJ20598.1 - 0.16 12.1 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A28 family ORC_WH_C PF18137.1 OAJ20644.1 - 3.8e-25 88.6 2.7 5.7e-25 88.0 0.0 2.6 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 OAJ20644.1 - 1.6e-12 47.2 10.0 1.9e-12 47.0 3.1 2.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus CCDC-167 PF15188.6 OAJ20644.1 - 3.7 8.0 4.7 1.2 9.5 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 F-box-like PF12937.7 OAJ20645.1 - 5.6e-05 22.9 0.3 0.00017 21.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 OAJ20645.1 - 0.024 14.7 4.4 34 4.8 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat TFIIF_alpha PF05793.12 OAJ20688.1 - 1 7.9 11.4 2.4 6.6 11.4 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Serglycin PF04360.12 OAJ20688.1 - 8.7 6.3 20.5 1.6 8.6 9.3 3.2 2 0 0 2 2 2 0 Serglycin DWNN PF08783.11 OAJ20689.1 - 3.9e-32 110.4 0.0 6.7e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 OAJ20689.1 - 1.6e-09 37.4 7.0 2.9e-09 36.6 7.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 OAJ20689.1 - 4.8e-06 26.4 1.7 9.4e-06 25.5 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ20689.1 - 0.0034 17.3 0.1 0.011 15.7 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 OAJ20689.1 - 0.0069 16.2 9.3 0.0069 16.2 9.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 OAJ20689.1 - 0.026 14.2 0.6 0.072 12.8 0.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-RING_2 PF13639.6 OAJ20689.1 - 2.8 8.3 10.9 5.9 7.3 10.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ20689.1 - 5 7.1 19.5 0.13 12.1 12.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CN_hydrolase PF00795.22 OAJ20690.1 - 1.8e-13 50.4 0.0 1.6e-07 30.9 0.0 3.7 3 1 1 4 4 4 3 Carbon-nitrogen hydrolase Flg_hook PF02120.16 OAJ20690.1 - 0.091 12.7 0.6 0.58 10.1 0.1 2.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Nop14 PF04147.12 OAJ20752.1 - 0.0025 16.1 8.8 0.0024 16.2 8.8 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ20752.1 - 0.023 14.1 10.8 0.025 14.0 10.8 1.1 1 0 0 1 1 1 0 SDA1 DUF4637 PF15470.6 OAJ20752.1 - 0.027 14.2 8.9 0.029 14.1 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 OAJ20752.1 - 0.058 11.7 8.6 0.058 11.7 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 OAJ20752.1 - 0.11 11.9 9.5 0.1 11.9 9.5 1.1 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 OAJ20752.1 - 0.41 10.4 9.7 0.88 9.3 8.5 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 OAJ20752.1 - 0.83 7.7 20.3 1 7.4 20.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 OAJ20752.1 - 2.8 6.3 16.7 3.2 6.1 16.7 1.0 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 OAJ20752.1 - 4.6 4.9 6.9 6 4.5 6.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RR_TM4-6 PF06459.12 OAJ20752.1 - 6.5 6.5 10.3 8 6.2 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sigma70_ner PF04546.13 OAJ20752.1 - 6.8 6.5 13.8 11 5.8 13.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 OAJ20752.1 - 8.9 5.6 20.8 12 5.1 20.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RVT_1 PF00078.27 OAJ20962.1 - 2.7e-22 79.4 0.0 4.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ20962.1 - 3.5e-16 59.1 0.0 6.3e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ20962.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Myb_DNA-bind_3 PF12776.7 OAJ20964.1 - 2.3e-14 54.2 0.6 3.5e-14 53.6 0.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ20964.1 - 0.0051 17.2 1.2 0.0082 16.5 0.4 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DDE_Tnp_4 PF13359.6 OAJ20965.1 - 4.8e-24 84.8 0.0 7.7e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ20965.1 - 4.2e-07 29.8 0.0 0.00026 20.7 0.0 2.5 3 0 0 3 3 3 2 Plant transposon protein DUF1793 PF08760.11 OAJ21021.1 - 2.7e-65 219.9 0.6 5.6e-65 218.8 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAJ21021.1 - 8e-64 214.5 0.0 1.3e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAJ21021.1 - 5e-47 160.6 1.8 1.2e-46 159.4 1.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 OAJ21021.1 - 5.9e-06 25.7 1.3 0.064 12.8 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 OAJ21021.1 - 0.0035 16.9 0.1 0.0086 15.6 0.1 1.6 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term zf-CCCH_3 PF15663.5 OAJ21083.1 - 0.36 11.1 4.8 6.6 7.0 4.7 2.1 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 OAJ21083.1 - 0.38 10.6 16.1 0.43 10.4 5.9 3.0 2 2 0 2 2 2 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ21083.1 - 0.6 10.2 11.2 1.2 9.3 0.3 3.3 3 0 0 3 3 3 0 Zinc finger domain zf-C3H1 PF10650.9 OAJ21083.1 - 0.89 9.3 6.6 1.1 9.1 1.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH PF00642.24 OAJ21083.1 - 1.2 9.2 13.0 4.6 7.3 1.0 2.4 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAJ21083.1 - 1.9 9.1 11.0 1.6 9.3 3.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger PAM2 PF07145.15 OAJ21083.1 - 4.2 7.3 6.2 2.5 8.0 0.2 3.2 3 0 0 3 3 3 0 Ataxin-2 C-terminal region MFS_1 PF07690.16 OAJ21084.1 - 1.7e-33 116.0 36.8 1.5e-27 96.5 0.4 3.2 2 1 1 3 3 3 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 OAJ21084.1 - 0.0093 15.7 0.0 0.096 12.5 0.0 2.4 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Tetraspanin PF00335.20 OAJ21085.1 - 0.0019 18.0 0.6 0.0026 17.5 0.6 1.2 1 0 0 1 1 1 1 Tetraspanin family Pkinase PF00069.25 OAJ21130.1 - 5.3e-70 235.8 0.0 7.6e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21130.1 - 4.6e-35 121.1 0.0 8.3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 OAJ21130.1 - 4.8e-06 26.3 0.0 0.00039 20.1 0.0 2.5 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 OAJ21130.1 - 0.00061 19.2 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ21130.1 - 0.0048 16.8 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ21130.1 - 0.0096 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ21130.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 OAJ21130.1 - 0.04 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Asp PF00026.23 OAJ21131.1 - 2.3e-27 96.3 0.0 3.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 OAJ21131.1 - 6.5e-06 26.7 0.1 0.0024 18.5 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ21131.1 - 0.005 17.4 0.0 0.069 13.7 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease PQ-loop PF04193.14 OAJ21188.1 - 5.9e-19 67.6 15.8 4.1e-10 39.3 0.2 3.2 3 0 0 3 3 3 2 PQ loop repeat BSP_II PF05432.11 OAJ21188.1 - 0.0023 17.7 1.3 0.0033 17.2 1.3 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF3328 PF11807.8 OAJ21188.1 - 0.0045 16.8 1.1 2 8.1 0.5 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3328) Bindin PF02084.15 OAJ21188.1 - 0.012 15.9 5.6 0.021 15.1 5.6 1.3 1 0 0 1 1 1 0 Bindin Syndecan PF01034.20 OAJ21188.1 - 0.21 11.6 0.0 0.21 11.6 0.0 3.0 3 0 0 3 3 2 0 Syndecan domain FAM176 PF14851.6 OAJ21188.1 - 0.33 10.6 4.3 1.5 8.4 2.5 2.3 2 0 0 2 2 2 0 FAM176 family DUF1218 PF06749.12 OAJ21188.1 - 0.39 11.3 8.4 12 6.5 1.8 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Astro_capsid_p PF12226.8 OAJ21188.1 - 0.43 9.7 4.3 0.68 9.0 4.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 OAJ21188.1 - 0.99 7.4 6.9 1.4 6.9 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2207 PF09972.9 OAJ21188.1 - 1 8.0 10.2 0.4 9.4 0.0 3.4 2 2 2 4 4 4 0 Predicted membrane protein (DUF2207) DUF4637 PF15470.6 OAJ21188.1 - 1.2 8.8 6.2 1.8 8.2 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2613 PF11021.8 OAJ21188.1 - 1.2 9.3 8.3 3.2 7.9 6.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Annexin PF00191.20 OAJ21189.1 - 7.4e-54 179.7 0.2 1.2e-13 50.9 0.1 4.1 4 0 0 4 4 4 4 Annexin Peptidase_M43 PF05572.13 OAJ21190.1 - 9.3e-17 61.3 0.1 1.4e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ21190.1 - 0.0015 19.0 0.1 0.0048 17.4 0.1 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ21190.1 - 0.0017 18.6 0.6 0.0032 17.6 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAJ21190.1 - 0.0018 18.1 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.16 OAJ21190.1 - 0.069 13.3 0.5 0.22 11.7 0.4 1.9 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.6 OAJ21190.1 - 0.075 12.7 0.2 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF2950 PF11453.8 OAJ21190.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF4953 PF16313.5 OAJ21190.1 - 0.21 10.8 0.5 0.41 9.8 0.5 1.4 1 0 0 1 1 1 0 Met-zincin DUF4407 PF14362.6 OAJ21191.1 - 0.5 9.7 9.8 0.58 9.5 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDK PF00334.19 OAJ21192.1 - 0.0006 19.8 0.0 0.00098 19.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pkinase PF00069.25 OAJ21243.1 - 4.8e-50 170.4 0.0 7e-30 104.3 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21243.1 - 4.3e-22 78.7 0.0 8.5e-14 51.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ21243.1 - 0.00015 21.2 0.0 0.046 13.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 OAJ21243.1 - 0.00067 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ21243.1 - 0.013 15.5 0.0 0.043 13.7 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ21243.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 OAJ21243.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIE-A_C PF11521.8 OAJ21243.1 - 2.5 8.5 8.0 0.59 10.5 3.7 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha TPR_2 PF07719.17 OAJ21245.1 - 0.0082 16.2 2.6 0.08 13.1 0.6 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_term_smal PF05944.12 OAJ21245.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Phage small terminase subunit TPR_16 PF13432.6 OAJ21245.1 - 0.86 10.3 10.4 1.1 10.0 1.2 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ21245.1 - 1.4 9.9 5.8 18 6.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DDE_1 PF03184.19 OAJ21295.1 - 2.7e-18 66.2 0.0 3.7e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 OAJ21295.1 - 0.028 14.2 0.0 0.16 11.8 0.0 2.2 2 1 1 3 3 3 0 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 OAJ21296.1 - 0.077 13.3 0.2 0.15 12.4 0.2 1.6 1 1 0 1 1 1 0 Transposase HTH_29 PF13551.6 OAJ21296.1 - 0.11 12.5 0.2 1.6 8.8 0.2 2.1 1 1 0 1 1 1 0 Winged helix-turn helix ABC2_membrane PF01061.24 OAJ21297.1 - 1.2e-39 136.0 18.7 1.2e-39 136.0 18.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ21297.1 - 5.3e-38 130.6 0.0 2.1e-18 67.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 OAJ21297.1 - 5.3e-28 96.8 0.1 5.3e-28 96.8 0.1 2.6 3 0 0 3 3 2 1 CDR ABC transporter ABC_trans_N PF14510.6 OAJ21297.1 - 1.9e-13 50.8 0.3 4.9e-13 49.5 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAJ21297.1 - 5.9e-07 30.0 0.2 8e-05 23.1 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ21297.1 - 1e-06 28.8 0.0 6.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 OAJ21297.1 - 0.00024 20.8 0.2 0.0035 16.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 OAJ21297.1 - 0.001 19.0 0.0 0.074 13.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 OAJ21297.1 - 0.0021 18.3 0.8 0.078 13.2 0.2 3.3 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 OAJ21297.1 - 0.0035 17.3 0.1 0.076 13.0 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 OAJ21297.1 - 0.0066 16.5 0.3 0.16 12.0 0.1 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAJ21297.1 - 0.014 15.1 0.1 0.47 10.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 OAJ21297.1 - 0.019 14.8 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DnaB_C PF03796.15 OAJ21297.1 - 0.021 14.2 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_29 PF13555.6 OAJ21297.1 - 0.022 14.5 0.3 0.38 10.5 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 OAJ21297.1 - 0.055 13.1 0.6 0.33 10.5 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 OAJ21297.1 - 0.061 13.8 0.3 2.9 8.3 0.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ter PF05472.11 OAJ21297.1 - 0.077 12.0 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) SMC_N PF02463.19 OAJ21297.1 - 0.094 12.1 0.0 7 6.0 0.0 2.9 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 OAJ21297.1 - 0.11 13.1 0.0 0.7 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 OAJ21297.1 - 0.13 12.5 0.1 0.53 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ21297.1 - 0.13 12.4 0.1 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 OAJ21298.1 - 8.2e-32 110.3 23.9 8.2e-32 110.3 23.9 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 OAJ21298.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 CDR ABC transporter DEAD PF00270.29 OAJ21354.1 - 1.9e-52 177.6 0.0 2.1e-51 174.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ21354.1 - 5e-32 110.5 0.0 4e-29 101.2 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ21354.1 - 4.4e-07 30.0 0.0 4.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ21354.1 - 0.0014 19.0 0.0 0.95 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.6 OAJ21354.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain UTP25 PF06862.12 OAJ21354.1 - 0.17 10.6 0.0 0.46 9.2 0.0 1.8 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Glyco_hydro_65m PF03632.15 OAJ21355.1 - 3.7e-38 131.4 2.3 5.9e-15 55.0 0.1 3.3 1 1 2 3 3 3 3 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 OAJ21355.1 - 4.6e-27 95.1 0.0 8.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 OAJ21355.1 - 5.3e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain F5_F8_type_C PF00754.25 OAJ21355.1 - 0.0037 17.4 0.0 0.034 14.3 0.0 2.6 2 1 0 2 2 2 1 F5/8 type C domain MobB PF03205.14 OAJ21355.1 - 0.038 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Borrelia_rep PF03183.13 OAJ21355.1 - 8.7 6.6 5.6 0.79 9.8 0.2 2.2 2 0 0 2 2 2 0 Borrelia repeat protein p450 PF00067.22 OAJ21356.1 - 2.4e-65 221.1 0.0 8.2e-50 169.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF1864 PF08933.11 OAJ21356.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) PLC-beta_C PF08703.10 OAJ21417.1 - 0.054 13.5 8.9 0.036 14.0 7.0 1.6 1 1 1 2 2 2 0 PLC-beta C terminal DUF4778 PF16008.5 OAJ21417.1 - 0.056 13.5 5.2 0.07 13.2 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Apolipoprotein PF01442.18 OAJ21417.1 - 0.12 12.3 18.4 0.18 11.6 18.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Muted PF14942.6 OAJ21417.1 - 0.5 10.7 12.0 0.51 10.7 10.3 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 OAJ21417.1 - 1 8.9 8.6 1.5 8.3 8.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TerB_C PF15615.6 OAJ21417.1 - 2 8.7 9.5 3.1 8.1 9.5 1.3 1 0 0 1 1 1 0 TerB-C domain Helitron_like_N PF14214.6 OAJ21418.1 - 2.8e-18 66.8 0.1 9.6e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ21418.1 - 1.8e-06 27.4 0.0 6.2e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 PIF1-like helicase MS_channel PF00924.18 OAJ21480.1 - 6e-15 55.4 0.5 1.6e-14 54.0 0.5 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 OAJ21480.1 - 8.6e-05 21.8 0.1 0.00019 20.7 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ21480.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 OAJ21480.1 - 0.0036 17.7 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair Spem1 PF15670.5 OAJ21480.1 - 0.0091 15.6 0.2 0.0091 15.6 0.2 2.7 2 1 0 2 2 2 1 Spermatid maturation protein 1 EF-hand_5 PF13202.6 OAJ21480.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 EF hand CCSAP PF15748.5 OAJ21480.1 - 4.3 7.4 22.9 0.15 12.2 14.2 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MS_channel PF00924.18 OAJ21481.1 - 9.8e-23 80.8 0.0 1.5e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.6 OAJ21481.1 - 0.0056 16.5 0.3 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 OAJ21481.1 - 0.034 13.7 0.0 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 OAJ21481.1 - 0.17 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 EF hand TFIIA PF03153.13 OAJ21481.1 - 2.3 8.1 28.1 0.075 13.0 16.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RAG1_imp_bd PF12560.8 OAJ21481.1 - 8 5.9 10.8 0.072 12.6 2.4 1.8 2 0 0 2 2 2 0 RAG1 importin binding ING PF12998.7 OAJ21482.1 - 7e-07 29.8 0.0 2.8e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ21482.1 - 0.00015 21.6 7.0 0.00025 20.9 7.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ21482.1 - 0.033 13.8 1.7 0.059 12.9 1.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 OAJ21482.1 - 0.14 12.5 1.9 0.29 11.4 1.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Neuromodulin PF06614.11 OAJ21535.1 - 0.0053 16.9 0.4 0.0071 16.5 0.4 1.1 1 0 0 1 1 1 1 Neuromodulin zf-BED PF02892.15 OAJ21536.1 - 0.00072 19.5 1.3 0.0018 18.2 1.3 1.6 1 0 0 1 1 1 1 BED zinc finger KDZ PF18758.1 OAJ21537.1 - 9.4e-39 133.3 0.0 9.4e-39 133.3 0.0 2.3 3 0 0 3 3 3 1 Kyakuja-Dileera-Zisupton transposase BAR_3 PF16746.5 OAJ21537.1 - 0.0033 17.2 3.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 BAR domain of APPL family Sigma_M_inh PF17453.2 OAJ21538.1 - 0.072 13.5 0.6 0.13 12.7 0.6 1.3 1 0 0 1 1 1 0 Sigma-M inhibitor LrgB PF04172.16 OAJ21539.1 - 4.7e-17 62.2 0.0 5.4e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 LrgB-like family PRCC PF10253.9 OAJ21584.1 - 1.6e-12 48.7 12.5 2.7e-12 48.0 12.5 1.4 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Macoilin PF09726.9 OAJ21584.1 - 6.2 5.2 9.2 4.9 5.6 7.2 1.8 2 0 0 2 2 2 0 Macoilin family DAD PF02109.16 OAJ21585.1 - 2.2e-46 156.7 2.7 3.1e-46 156.2 2.7 1.2 1 0 0 1 1 1 1 DAD family Pex14_N PF04695.13 OAJ21585.1 - 0.014 16.1 9.0 0.024 15.3 9.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MDFI PF15316.6 OAJ21585.1 - 0.019 15.0 0.6 0.026 14.6 0.6 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Med13_C PF06333.12 OAJ21585.1 - 0.021 14.1 4.3 0.02 14.2 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Rotamase_2 PF13145.6 OAJ21585.1 - 0.47 11.3 6.2 0.17 12.8 3.9 1.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain MAGE_N PF12440.8 OAJ21585.1 - 3.7 8.3 23.0 6.4 7.5 23.0 1.4 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Calpain_inhib PF00748.19 OAJ21585.1 - 5.6 7.5 13.7 11 6.5 13.7 1.5 1 0 0 1 1 1 0 Calpain inhibitor Alpha_GJ PF03229.13 OAJ21585.1 - 8.9 6.9 14.5 9.9 6.7 10.8 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J Spt20 PF12090.8 OAJ21585.1 - 9 5.8 11.8 12 5.4 11.8 1.2 1 0 0 1 1 1 0 Spt20 family Paf1 PF03985.13 OAJ21586.1 - 3e-43 148.4 33.6 1.8e-22 80.0 0.0 4.9 4 1 1 5 5 5 3 Paf1 Pex24p PF06398.11 OAJ21587.1 - 0.00014 21.0 2.0 0.00026 20.1 2.0 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin ATP-synt_B PF00430.18 OAJ21587.1 - 5.1 7.2 12.4 7.3 6.7 12.4 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) NDC10_II PF16787.5 OAJ21645.1 - 1.3e-62 211.7 0.0 2e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ21645.1 - 8.8e-18 64.4 0.3 2.1e-17 63.2 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Xpo1 PF08389.12 OAJ21645.1 - 0.035 14.2 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Exportin 1-like protein Phage_int_SAM_4 PF13495.6 OAJ21645.1 - 1.7 9.2 3.8 25 5.4 0.1 2.8 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 OAJ21645.1 - 2.4 8.5 9.0 5.3 7.4 0.1 4.5 4 1 1 5 5 5 0 Phage integrase, N-terminal SAM-like domain Plant_tran PF04827.14 OAJ21646.1 - 0.044 13.4 0.0 0.058 13.0 0.0 1.1 1 0 0 1 1 1 0 Plant transposon protein DDE_Tnp_4 PF13359.6 OAJ21646.1 - 0.054 13.2 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease PDT PF00800.18 OAJ21705.1 - 1.9e-41 141.9 0.0 2.8e-35 121.8 0.0 3.4 2 2 0 2 2 2 2 Prephenate dehydratase Pkinase PF00069.25 OAJ21706.1 - 6.6e-34 117.5 0.0 2e-10 40.5 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ21706.1 - 5e-15 55.5 0.0 4.5e-08 32.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ21706.1 - 0.00071 19.6 0.1 0.003 17.5 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family F-box PF00646.33 OAJ21706.1 - 0.028 14.3 2.4 0.079 12.9 2.4 1.8 1 0 0 1 1 1 0 F-box domain ubiquitin PF00240.23 OAJ21707.1 - 4.5e-34 116.0 0.7 6e-34 115.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 OAJ21707.1 - 4.6e-29 100.1 9.0 7e-29 99.5 9.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 OAJ21707.1 - 3.5e-16 58.8 0.8 4.6e-16 58.4 0.8 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ21707.1 - 2e-05 25.0 0.2 7.4e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ21707.1 - 0.0041 17.0 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ21707.1 - 0.0056 17.0 0.1 0.0091 16.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ21707.1 - 0.0074 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ21707.1 - 0.014 15.9 0.1 0.023 15.2 0.1 1.5 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ21707.1 - 0.015 15.3 1.1 4.4 7.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_L18A PF01775.17 OAJ21708.1 - 1.4e-52 176.9 0.2 1.7e-52 176.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Transposase_21 PF02992.14 OAJ21765.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 6PGD PF00393.19 OAJ21831.1 - 6.1e-48 163.7 0.0 8.3e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 OAJ21831.1 - 6.7e-14 52.4 0.1 1.1e-13 51.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 OAJ21831.1 - 4.2e-10 39.6 8.6 6.5e-10 39.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_11 PF14833.6 OAJ21831.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Cgr1 PF03879.14 OAJ21832.1 - 9.9e-15 54.8 22.7 1.1e-14 54.7 22.7 1.0 1 0 0 1 1 1 1 Cgr1 family Titin_Z PF09042.11 OAJ21832.1 - 0.13 12.3 1.2 0.13 12.3 1.2 2.4 1 1 1 2 2 2 0 Titin Z PEARLI-4 PF05278.12 OAJ21832.1 - 0.53 9.8 11.2 0.62 9.6 11.2 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Di19_C PF14571.6 OAJ21832.1 - 1.4 9.5 6.0 0.56 10.8 3.7 1.5 1 1 1 2 2 2 0 Stress-induced protein Di19, C-terminal MIP PF00230.20 OAJ21833.1 - 8.1e-41 140.2 13.4 1.1e-40 139.8 13.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Metallophos PF00149.28 OAJ21834.1 - 4.4e-37 128.6 0.1 6.9e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 OAJ21834.1 - 0.0042 16.7 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 OAJ21834.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF5378 PF17349.2 OAJ21834.1 - 0.24 10.7 0.0 0.35 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Atg14 PF10186.9 OAJ21836.1 - 2.1e-14 53.4 6.3 1.6e-08 34.0 0.0 3.6 3 1 0 3 3 3 3 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 OAJ21836.1 - 0.24 11.3 1.4 0.44 10.5 1.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COesterase PF00135.28 OAJ21906.1 - 5.3e-07 28.9 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ21906.1 - 0.00025 21.0 0.8 0.0032 17.3 0.0 2.9 3 1 1 4 4 4 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ21906.1 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ21906.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SH3_1 PF00018.28 OAJ21907.1 - 6.9e-38 128.0 8.5 5.1e-16 58.0 0.2 4.5 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 OAJ21907.1 - 9.3e-37 124.7 10.9 2.3e-13 49.8 0.3 4.0 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 OAJ21907.1 - 1.2e-28 98.7 0.0 2.4e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 OAJ21907.1 - 6.7e-21 73.7 0.0 3.6e-07 29.8 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 OAJ21907.1 - 0.00027 20.8 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 OAJ21907.1 - 0.0015 18.5 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 OAJ21907.1 - 0.0038 17.5 2.3 0.086 13.1 0.1 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain Lactamase_B_2 PF12706.7 OAJ21908.1 - 2.8e-07 30.3 0.0 3e-05 23.6 0.0 2.7 2 1 1 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ21908.1 - 5.3e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ21908.1 - 0.00017 21.6 0.0 0.00055 20.0 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 OAJ21908.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Peptidase_C48 PF02902.19 OAJ21968.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MULE PF10551.9 OAJ21969.1 - 5.5e-13 49.1 0.2 5.2e-08 33.2 0.1 2.7 1 1 1 2 2 2 2 MULE transposase domain Ribosomal_60s PF00428.19 OAJ21969.1 - 0.26 11.9 8.1 4.8 7.8 5.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein E7 PF00527.18 OAJ21969.1 - 2.3 8.5 5.2 42 4.4 0.7 3.0 3 0 0 3 3 3 0 E7 protein, Early protein LTXXQ PF07813.12 OAJ22026.1 - 0.28 11.9 4.5 1.2 9.9 0.6 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein F-box-like PF12937.7 OAJ22027.1 - 0.00013 21.8 0.1 0.00027 20.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like LRV PF01816.17 OAJ22028.1 - 0.19 12.2 2.1 0.47 11.0 2.1 1.7 1 0 0 1 1 1 0 Leucine rich repeat variant RVT_1 PF00078.27 OAJ22029.1 - 8.9e-18 64.6 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4112 PF13430.6 OAJ22029.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) LRR_4 PF12799.7 OAJ22083.1 - 1.4e-08 34.9 0.8 0.76 10.3 0.1 5.9 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 OAJ22083.1 - 3.5e-05 23.6 2.9 3.5e-05 23.6 2.9 2.5 3 0 0 3 3 3 1 F-box-like CRAL_TRIO PF00650.20 OAJ22084.1 - 8.1e-36 123.1 0.1 1.3e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ22084.1 - 1.1e-11 44.8 0.2 1.1e-11 44.8 0.2 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain DNA_repr_REX1B PF14966.6 OAJ22204.1 - 0.0011 19.6 7.1 0.22 12.2 0.1 4.0 3 1 0 3 3 3 2 DNA repair REX1-B DUF5132 PF17195.4 OAJ22204.1 - 0.48 10.5 2.6 1.1 9.4 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) GvpL_GvpF PF06386.11 OAJ22204.1 - 2.2 8.1 11.0 0.91 9.4 5.9 2.0 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF SUI1 PF01253.22 OAJ22205.1 - 0.055 14.0 0.1 0.15 12.6 0.1 1.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Cyt-b5 PF00173.28 OAJ22206.1 - 9.3e-09 35.3 0.1 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.18 OAJ22207.1 - 1.8e-19 69.8 0.2 5.9e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ22207.1 - 2.1e-09 37.4 2.4 4e-09 36.5 2.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ22207.1 - 0.0012 18.9 29.8 0.0038 17.3 3.9 3.4 3 0 0 3 3 3 3 Transcription factor IIA, alpha/beta subunit AIP3 PF03915.13 OAJ22362.1 - 4.5e-121 404.8 0.0 7e-121 404.1 0.0 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 DUF1640 PF07798.11 OAJ22362.1 - 0.019 15.0 0.2 0.069 13.2 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Halo_GVPC PF05465.13 OAJ22362.1 - 0.4 11.0 2.8 0.82 10.0 0.3 2.6 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat FliJ PF02050.16 OAJ22362.1 - 0.89 9.8 3.6 7.1 6.9 0.0 3.3 3 0 0 3 3 3 0 Flagellar FliJ protein Tma16 PF11176.8 OAJ22363.1 - 7e-40 136.3 0.0 8.6e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF5436 PF17504.2 OAJ22363.1 - 0.11 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5436) Bud13 PF09736.9 OAJ22364.1 - 1.2e-27 97.1 0.1 1.7e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex 4HBT_3 PF13622.6 OAJ22365.1 - 1.3e-29 104.2 1.1 5.6e-29 102.1 1.1 1.9 1 1 0 1 1 1 1 Thioesterase-like superfamily PigN PF04987.14 OAJ22366.1 - 0.24 10.2 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Glycogen_syn PF05693.13 OAJ22366.1 - 6.3 5.2 4.5 11 4.5 4.5 1.3 1 0 0 1 1 1 0 Glycogen synthase Chromate_transp PF02417.15 OAJ22452.1 - 6.4e-58 195.4 35.5 1.2e-33 116.5 12.7 2.5 3 0 0 3 3 3 2 Chromate transporter HEAT_EZ PF13513.6 OAJ22453.1 - 1.6e-05 25.2 4.2 0.004 17.6 0.2 2.8 2 2 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 OAJ22453.1 - 0.00056 19.9 4.4 0.028 14.7 0.1 3.8 3 1 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 OAJ22453.1 - 0.0011 19.4 3.2 0.59 10.6 0.4 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT_PBS PF03130.16 OAJ22453.1 - 8.3 7.4 7.7 28 5.7 0.6 3.0 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat MFS_1 PF07690.16 OAJ22533.1 - 5.3e-09 35.5 19.9 5.3e-09 35.5 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1761 PF08570.10 OAJ22533.1 - 0.52 10.6 12.7 0.11 12.7 0.7 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) Baculo_PEP_C PF04513.12 OAJ22535.1 - 0.17 11.9 7.7 1.4 9.0 1.2 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_17 PF00332.18 OAJ22536.1 - 2.2e-08 34.1 0.3 0.00019 21.1 0.2 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Peptidase_M16 PF00675.20 OAJ22618.1 - 1.1e-49 168.3 3.9 1.9e-49 167.5 2.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ22618.1 - 1.7e-39 135.7 0.0 1.4e-36 126.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain zf-C3HC4 PF00097.25 OAJ22619.1 - 1.1e-08 34.8 1.3 1.1e-08 34.8 1.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ22619.1 - 1.9e-07 30.8 1.6 2.2e-05 24.2 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ22619.1 - 2.6e-06 27.3 4.3 5.8e-06 26.2 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ22619.1 - 4.2e-05 23.3 2.9 4.2e-05 23.3 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ22619.1 - 7.7e-05 22.9 2.4 7.7e-05 22.9 2.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ22619.1 - 0.00045 20.3 2.3 0.00097 19.2 2.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ22619.1 - 0.0011 18.7 4.9 0.024 14.5 3.1 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ22619.1 - 0.0011 18.8 2.3 0.0011 18.8 2.3 2.0 2 0 0 2 2 2 1 zinc-RING finger domain DUF1644 PF07800.12 OAJ22619.1 - 0.15 12.1 2.5 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) zf-ANAPC11 PF12861.7 OAJ22619.1 - 0.24 11.5 3.8 0.36 10.9 1.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAJ22619.1 - 0.24 11.7 1.7 1.1 9.6 0.3 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Malate_synthase PF01274.22 OAJ22700.1 - 1.8e-203 676.6 0.0 2.3e-203 676.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase SecE PF00584.20 OAJ22786.1 - 3.5e-15 55.7 0.0 3.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Aminotran_1_2 PF00155.21 OAJ22787.1 - 1.9e-20 73.3 0.0 5.9e-20 71.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ22787.1 - 0.00032 19.4 0.0 0.00053 18.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF3153 PF11353.8 OAJ22787.1 - 0.14 11.7 0.0 0.56 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) TFB6 PF17110.5 OAJ22788.1 - 7.8 6.2 12.9 13 5.5 3.0 3.9 4 0 0 4 4 4 0 Subunit 11 of the general transcription factor TFIIH Herpes_gI PF01688.17 OAJ22806.1 - 0.06 13.3 0.7 0.25 11.3 0.1 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein I MULE PF10551.9 OAJ22807.1 - 3e-07 30.8 0.0 7.4e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.17 OAJ22807.1 - 0.018 14.7 0.9 0.018 14.7 0.9 2.5 2 0 0 2 2 2 0 SWIM zinc finger Carn_acyltransf PF00755.20 OAJ22911.1 - 7.7e-91 305.5 0.0 9.1e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase IMUP PF15761.5 OAJ22912.1 - 1.6 9.5 7.9 1.2 9.8 5.9 1.9 1 1 0 1 1 1 0 Immortalisation up-regulated protein Myb_DNA-bind_4 PF13837.6 OAJ22913.1 - 0.003 17.9 2.2 0.04 14.3 0.0 2.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Glyco_hydro_47 PF01532.20 OAJ22914.1 - 2.5e-150 501.4 0.0 2.9e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TauD PF02668.16 OAJ22915.1 - 1.8e-51 175.5 2.8 2.3e-51 175.2 2.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TFIIA PF03153.13 OAJ22932.1 - 2.9 7.8 20.6 0.28 11.1 11.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-CCHC_4 PF14392.6 OAJ22932.1 - 5.2 6.9 7.1 5.8 6.7 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 OAJ22933.1 - 1.2e-14 53.9 0.4 2.4e-14 52.9 0.4 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 OAJ22933.1 - 0.00015 22.1 0.1 0.0028 18.0 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) HAUS6_N PF14661.6 OAJ22933.1 - 0.017 14.7 0.0 0.052 13.1 0.0 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3509 PF12021.8 OAJ22933.1 - 0.12 12.1 0.1 5.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Pkinase PF00069.25 OAJ22934.1 - 9.6e-20 71.0 0.0 2.6e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ22934.1 - 1.1e-12 47.7 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ22934.1 - 0.00022 20.6 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Kinase-like Fuseless PF15993.5 OAJ22934.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Fuseless DNA_pol_viral_C PF00336.18 OAJ22935.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain MULE PF10551.9 OAJ22955.1 - 4.7e-18 65.4 0.0 1.6e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ22955.1 - 2.1e-11 43.4 0.0 3.4e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.17 OAJ22955.1 - 4.3e-06 26.3 0.3 8.9e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger DDE_Tnp_IS240 PF13610.6 OAJ22955.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 DDE domain DDE_Tnp_ISL3 PF01610.17 OAJ22955.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.6 1 1 0 1 1 1 0 Transposase HA2 PF04408.23 OAJ22973.1 - 3.8e-18 65.8 1.0 1.9e-17 63.5 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ22973.1 - 1.9e-15 57.2 0.1 4.6e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 OAJ22973.1 - 7.6e-11 42.2 0.1 1.6e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 OAJ22973.1 - 8e-07 29.4 0.2 4.5e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAJ22973.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 OAJ22973.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 OAJ22973.1 - 0.63 10.5 1.6 1.1 9.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF3035 PF11233.8 OAJ22973.1 - 4 7.7 14.9 0.045 14.0 5.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Abhydrolase_5 PF12695.7 OAJ22974.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 OAJ22974.1 - 0.11 13.1 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1491 PF07372.12 OAJ22975.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Forkhead PF00250.18 OAJ22991.1 - 1.3e-22 79.8 0.0 2.6e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain tRNA-synt_2d PF01409.20 OAJ22992.1 - 1.7e-86 289.7 0.0 2.3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 OAJ22992.1 - 1.3e-14 54.2 1.3 2.4e-14 53.3 0.1 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 OAJ22992.1 - 5.8e-08 32.4 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 OAJ22992.1 - 6.2e-05 22.2 0.3 0.0021 17.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 OAJ22992.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 OAJ22992.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Keratin_2_head PF16208.5 OAJ23012.1 - 0.033 14.3 10.4 0.04 14.0 10.4 1.1 1 0 0 1 1 1 0 Keratin type II head Aldo_ket_red PF00248.21 OAJ23013.1 - 3.9e-46 157.6 0.0 4.8e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HxlR PF01638.17 OAJ23013.1 - 0.056 13.3 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 HxlR-like helix-turn-helix NUP PF06516.11 OAJ23014.1 - 2.2e-121 404.9 0.2 2.6e-121 404.7 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) zf-C3HC4 PF00097.25 OAJ23015.1 - 1.6e-07 31.1 1.2 1.6e-07 31.1 1.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ23015.1 - 2.2e-06 27.4 5.2 5e-06 26.3 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ23015.1 - 2.8e-06 27.6 3.9 9.4e-06 25.9 1.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ23015.1 - 4.3e-06 26.6 2.8 4.3e-06 26.6 2.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ23015.1 - 8.6e-06 25.5 4.5 6.2e-05 22.8 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ23015.1 - 0.00035 20.5 1.6 0.00035 20.5 1.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 OAJ23015.1 - 0.002 18.2 4.1 0.002 18.2 4.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ23015.1 - 0.17 11.8 6.6 1.4 8.8 2.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ23015.1 - 0.18 12.1 1.2 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain MAJIN PF15077.6 OAJ23015.1 - 6.1 6.6 7.4 0.29 10.9 0.8 2.1 3 0 0 3 3 3 0 Membrane-anchored junction protein Methyltransf_23 PF13489.6 OAJ23016.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 OAJ23016.1 - 0.02 15.4 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Rhodanese-like domain Methyltransf_25 PF13649.6 OAJ23016.1 - 0.14 12.9 0.2 0.68 10.7 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ23016.1 - 0.17 11.7 0.0 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain AA_permease_2 PF13520.6 OAJ23035.1 - 2.7e-57 194.5 50.0 3.4e-57 194.2 50.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ23035.1 - 4.3e-09 35.5 49.2 9.6e-09 34.3 49.2 1.5 1 1 0 1 1 1 1 Amino acid permease HIG_1_N PF04588.13 OAJ23036.1 - 1e-05 25.7 1.1 2.5e-05 24.4 1.1 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region ENOD93 PF03386.14 OAJ23036.1 - 0.017 15.0 0.5 0.032 14.1 0.1 1.6 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein TctA PF01970.16 OAJ23036.1 - 0.037 12.7 0.0 0.059 12.1 0.0 1.2 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Opi1 PF08618.10 OAJ23037.1 - 5.8e-62 210.3 4.3 5.8e-62 210.3 4.3 4.0 3 2 0 3 3 3 1 Transcription factor Opi1 Ig_mannosidase PF17753.1 OAJ23054.1 - 9.2e-16 57.4 0.2 5.1e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 OAJ23054.1 - 5.1e-09 36.6 0.1 2.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 OAJ23054.1 - 3.7e-08 34.0 0.1 7.8e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Membr_traf_MHD PF10540.9 OAJ23055.1 - 4.1e-15 56.2 0.4 1e-07 32.3 0.7 2.5 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 OAJ23055.1 - 5.2e-08 33.1 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 OAJ23078.1 - 2.8e-40 138.4 0.0 5.8e-24 84.9 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23078.1 - 1.2e-22 80.5 0.0 7.5e-16 58.2 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Serglycin PF04360.12 OAJ23078.1 - 0.11 12.5 8.2 0.34 10.8 8.2 1.8 1 0 0 1 1 1 0 Serglycin Kinase-like PF14531.6 OAJ23078.1 - 0.12 11.7 0.0 4.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FhuF PF06276.12 OAJ23078.1 - 0.12 12.7 0.1 0.26 11.7 0.1 1.4 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter APH PF01636.23 OAJ23078.1 - 0.2 11.6 2.3 0.58 10.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family LSM PF01423.22 OAJ23079.1 - 3e-15 55.7 0.0 4.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ23079.1 - 0.001 19.2 0.0 0.0012 18.9 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain DUF150_C PF17384.2 OAJ23079.1 - 0.06 13.5 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Sds3 PF08598.11 OAJ23098.1 - 6.2e-29 101.6 2.3 1.2e-28 100.6 2.3 1.5 1 0 0 1 1 1 1 Sds3-like Y_phosphatase2 PF03162.13 OAJ23099.1 - 6e-31 107.2 0.0 1.3e-23 83.4 0.0 3.1 3 0 0 3 3 3 3 Tyrosine phosphatase family CoA_trans PF01144.23 OAJ23100.1 - 6.7e-105 349.3 0.2 2.6e-64 216.6 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 OAJ23100.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter AcetylCoA_hyd_C PF13336.6 OAJ23100.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain PSCyt1 PF07635.11 OAJ23101.1 - 0.29 11.7 2.5 2.8 8.6 1.1 2.2 2 0 0 2 2 2 0 Planctomycete cytochrome C B56 PF01603.20 OAJ23110.1 - 6.1e-192 638.1 2.8 7.2e-192 637.9 2.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Hat1_N PF10394.9 OAJ23111.1 - 1.2e-43 149.1 0.0 3e-43 147.8 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 OAJ23111.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ23111.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 OAJ23111.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Phage_integrase PF00589.22 OAJ23125.1 - 0.063 13.1 1.1 0.22 11.3 0.0 2.5 4 0 0 4 4 4 0 Phage integrase family SPX PF03105.19 OAJ23126.1 - 0.3 11.0 43.8 0.17 11.7 7.9 2.4 2 0 0 2 2 2 0 SPX domain NDC10_II PF16787.5 OAJ23127.1 - 8.9e-58 195.8 0.0 2.2e-57 194.5 0.0 1.6 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ23127.1 - 1.9e-19 69.8 1.1 3.4e-19 68.9 1.1 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Cellulase PF00150.18 OAJ23147.1 - 0.0024 17.3 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Forkhead PF00250.18 OAJ23148.1 - 2.2e-12 47.1 0.0 5.6e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Forkhead domain TFIIA PF03153.13 OAJ23148.1 - 0.013 15.5 27.3 0.11 12.4 4.5 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF533 PF04391.12 OAJ23148.1 - 4.1 6.9 19.8 0.22 11.1 4.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF533) SWIM PF04434.17 OAJ23169.1 - 0.0003 20.4 0.1 0.00066 19.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger FAR1 PF03101.15 OAJ23172.1 - 0.024 15.3 0.3 0.043 14.5 0.3 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain ALS2CR8 PF15299.6 OAJ23172.1 - 0.1 12.5 2.8 0.41 10.5 0.3 2.1 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Aldedh PF00171.22 OAJ23173.1 - 1.6e-11 43.4 0.1 2.1e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1325 PF07039.11 OAJ23173.1 - 3.5e-09 36.9 0.0 4.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain PGM_PMM_I PF02878.16 OAJ23173.1 - 0.0021 17.7 0.0 0.0044 16.7 0.0 1.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Aldedh PF00171.22 OAJ23174.1 - 5.7e-22 77.9 0.0 6.6e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sulfate_transp PF00916.20 OAJ23192.1 - 1e-12 47.6 0.7 1e-12 47.6 0.7 1.4 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 OAJ23192.1 - 2e-11 43.8 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 OAJ23192.1 - 2.3e-10 40.1 0.1 5.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 OAJ23193.1 - 1e-13 50.9 3.1 5.4e-07 28.7 0.2 2.3 2 0 0 2 2 2 2 Sulfate permease family KilA-N PF04383.13 OAJ23209.1 - 0.001 18.9 0.0 1.7 8.5 0.0 2.3 1 1 1 2 2 2 2 KilA-N domain SAM_2 PF07647.17 OAJ23209.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WD40 PF00400.32 OAJ23210.1 - 1.2e-11 45.0 17.1 0.00015 22.5 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAJ23210.1 - 0.024 13.2 0.0 1.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Es2 PF09751.9 OAJ23211.1 - 1.9e-71 242.1 17.9 1.9e-71 242.1 17.9 2.4 2 1 0 2 2 2 1 Nuclear protein Es2 QRPTase_C PF01729.19 OAJ23212.1 - 2.5e-42 144.5 0.4 1.5e-40 138.7 0.4 2.1 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 OAJ23212.1 - 2.1e-17 63.0 0.1 7.7e-16 57.9 0.1 2.8 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain IMUP PF15761.5 OAJ23212.1 - 0.17 12.6 1.8 0.38 11.5 1.8 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Trimer_CC PF08954.11 OAJ23232.1 - 0.089 12.4 0.1 3.2 7.4 0.0 2.8 2 1 1 3 3 3 0 Trimerisation motif E2_bind PF08825.10 OAJ23232.1 - 0.1 12.7 0.8 0.18 12.0 0.8 1.4 1 0 0 1 1 1 0 E2 binding domain HTH_37 PF13744.6 OAJ23232.1 - 0.18 11.8 0.3 0.18 11.8 0.3 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain Zn_clus PF00172.18 OAJ23234.1 - 3.4e-05 23.9 8.0 6e-05 23.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ23234.1 - 1.9 8.4 16.2 2 8.4 9.3 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PITH PF06201.13 OAJ23235.1 - 1.1e-19 71.1 0.0 4e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 PITH domain MTHFR PF02219.17 OAJ23273.1 - 1.9e-110 368.7 0.0 2.5e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF4609 PF15382.6 OAJ23274.1 - 0.16 11.9 0.1 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) TP2 PF01254.18 OAJ23276.1 - 7.6 7.2 13.0 0.52 10.9 7.7 1.7 2 0 0 2 2 2 0 Nuclear transition protein 2 Cyt-b5 PF00173.28 OAJ23292.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LETM1 PF07766.13 OAJ23293.1 - 1.5e-100 336.0 1.7 1.5e-100 336.0 1.7 2.2 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 OAJ23293.1 - 2.1e-05 24.9 3.8 0.0036 17.7 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 OAJ23293.1 - 0.0033 17.2 2.2 3.8 7.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 OAJ23293.1 - 0.0066 16.3 0.1 0.02 14.7 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAJ23293.1 - 0.094 12.3 2.8 4.1 7.2 0.0 3.5 4 0 0 4 4 4 0 EF hand DUF1682 PF07946.14 OAJ23293.1 - 0.53 9.4 10.4 0.9 8.7 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ALMT PF11744.8 OAJ23293.1 - 0.89 8.3 10.6 1.5 7.5 10.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 OAJ23293.1 - 5.6 4.8 6.6 9 4.1 6.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rot1 PF10681.9 OAJ23294.1 - 5.5e-55 186.1 0.9 8.1e-55 185.6 0.9 1.2 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal NAD_synthase PF02540.17 OAJ23295.1 - 2.6e-23 82.4 0.0 1.3e-19 70.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.22 OAJ23295.1 - 4e-21 75.5 0.0 6.2e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DSBA PF01323.20 OAJ23308.1 - 3.5e-25 88.9 0.0 4.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Opi1 PF08618.10 OAJ23309.1 - 0.18 11.0 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 Aldo_ket_red PF00248.21 OAJ23310.1 - 4.8e-46 157.3 0.0 2.8e-44 151.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RNA_pol_I_A49 PF06870.12 OAJ23332.1 - 3e-73 246.9 0.0 1.1e-72 245.0 0.0 1.7 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_23 PF13489.6 OAJ23332.1 - 6.1e-16 58.7 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ23332.1 - 2.5e-08 34.6 0.0 5.5e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ23332.1 - 7.4e-08 32.9 0.0 1.9e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ23332.1 - 0.00032 21.3 0.0 0.00076 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ23332.1 - 0.0014 18.4 0.0 0.0041 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 OAJ23332.1 - 0.0017 17.3 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 OAJ23332.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Asp PF00026.23 OAJ23344.1 - 2.8e-46 158.4 0.0 8.2e-29 101.0 0.1 3.4 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ23344.1 - 0.015 15.6 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ23344.1 - 0.058 13.2 0.3 0.6 9.9 0.0 2.5 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal DUF2781 PF10914.8 OAJ23345.1 - 4.6e-34 117.9 7.6 5.3e-34 117.7 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Zn_clus PF00172.18 OAJ23346.1 - 1.5e-06 28.2 9.6 2.6e-06 27.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 OAJ23360.1 - 1.8e-06 27.6 0.0 0.00073 19.1 0.0 2.0 1 1 1 2 2 2 2 Proteasome subunit CHCH PF06747.13 OAJ23361.1 - 0.00012 22.1 5.1 0.00012 22.1 5.1 2.5 2 1 0 2 2 2 1 CHCH domain CX9C PF16860.5 OAJ23361.1 - 0.00019 21.4 10.7 0.0036 17.3 3.6 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ23361.1 - 0.12 12.7 9.0 4 7.8 0.6 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 OAJ23361.1 - 8.2 6.9 11.0 2.1 8.8 4.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) FAD-oxidase_C PF02913.19 OAJ23362.1 - 6.3e-62 209.4 0.0 1e-61 208.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ23362.1 - 1.3e-33 115.7 1.1 2.6e-33 114.7 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain Relaxase PF03432.14 OAJ23362.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain Ilar_coat PF01787.16 OAJ23362.1 - 0.22 11.3 0.6 0.83 9.4 0.0 2.1 2 1 0 2 2 2 0 Ilarvirus coat protein MMR_HSR1 PF01926.23 OAJ23363.1 - 5e-16 58.8 0.0 1e-14 54.6 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ23363.1 - 2.3e-06 27.2 0.0 2.2e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ23363.1 - 1.6e-05 24.8 0.2 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 OAJ23363.1 - 0.0016 17.8 0.0 0.0055 16.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family SDA1 PF05285.12 OAJ23363.1 - 0.0074 15.7 14.0 0.011 15.2 14.0 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OAJ23363.1 - 0.011 14.0 10.7 0.016 13.6 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 OAJ23363.1 - 0.012 15.8 16.2 0.025 14.8 16.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.12 OAJ23363.1 - 0.022 13.3 16.8 0.03 12.8 16.8 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 OAJ23363.1 - 0.1 11.9 14.6 0.15 11.3 14.6 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 OAJ23363.1 - 0.21 11.0 18.8 0.35 10.2 18.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dynamin_N PF00350.23 OAJ23363.1 - 0.36 10.9 6.5 0.25 11.4 0.6 2.9 3 1 1 4 4 4 0 Dynamin family MscS_TM PF12794.7 OAJ23363.1 - 0.52 9.1 4.5 0.81 8.5 4.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nop14 PF04147.12 OAJ23363.1 - 0.89 7.7 22.3 1.2 7.2 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.6 OAJ23363.1 - 0.92 9.9 6.5 12 6.3 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain Pox_Ag35 PF03286.14 OAJ23363.1 - 1 9.1 15.8 2.3 8.0 15.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RPN2_C PF18004.1 OAJ23363.1 - 1.5 8.8 7.2 3.1 7.7 7.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 OAJ23363.1 - 2.4 8.1 9.1 5.9 6.9 9.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 OAJ23363.1 - 3.2 7.4 18.9 5.4 6.7 18.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 OAJ23363.1 - 5.2 5.7 7.5 7 5.3 7.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA PF00004.29 OAJ23364.1 - 1.4e-90 300.6 0.0 4.5e-46 156.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ23364.1 - 7.2e-22 76.9 5.7 1.4e-10 40.8 1.6 2.8 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 OAJ23364.1 - 6.2e-14 52.0 0.0 2.2e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ23364.1 - 2.1e-11 44.5 5.5 0.0017 18.8 0.0 5.0 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 OAJ23364.1 - 4e-11 43.3 0.7 0.014 15.7 0.0 4.9 2 2 1 3 3 2 2 AAA domain AAA_2 PF07724.14 OAJ23364.1 - 8.7e-11 42.2 0.0 0.00024 21.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAJ23364.1 - 1.1e-10 41.7 0.3 0.00081 19.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 OAJ23364.1 - 1.7e-09 37.4 0.0 2.6e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 OAJ23364.1 - 1.7e-08 34.7 0.0 0.0065 16.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 OAJ23364.1 - 4.1e-07 29.6 2.0 0.02 14.2 0.0 2.8 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 OAJ23364.1 - 4.4e-07 30.0 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAJ23364.1 - 7.1e-07 29.6 0.0 0.057 13.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAJ23364.1 - 1.3e-06 28.3 0.0 0.037 13.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 OAJ23364.1 - 1.3e-06 28.7 0.0 0.034 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 OAJ23364.1 - 2.6e-06 27.4 0.9 0.037 13.9 0.1 3.7 3 1 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 OAJ23364.1 - 5.1e-06 27.0 0.0 0.092 13.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter TsaE PF02367.17 OAJ23364.1 - 9.8e-06 25.6 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAJ23364.1 - 1.5e-05 25.5 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 OAJ23364.1 - 4.1e-05 23.2 1.9 1.2 8.7 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_3 PF07726.11 OAJ23364.1 - 5.7e-05 23.0 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ23364.1 - 9.4e-05 22.2 0.1 0.49 10.1 0.0 4.0 4 0 0 4 4 4 1 Sigma-54 interaction domain Rad17 PF03215.15 OAJ23364.1 - 0.00011 22.1 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain ATPase PF06745.13 OAJ23364.1 - 0.00012 21.6 0.1 1.8 7.9 0.0 3.2 3 0 0 3 3 3 1 KaiC AAA_17 PF13207.6 OAJ23364.1 - 0.00019 21.9 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ23364.1 - 0.00028 20.2 0.1 0.69 9.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Viral_helicase1 PF01443.18 OAJ23364.1 - 0.00038 20.3 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 OAJ23364.1 - 0.0005 20.3 0.0 0.06 13.5 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family NB-ARC PF00931.22 OAJ23364.1 - 0.00071 18.8 0.0 0.86 8.7 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain AAA_11 PF13086.6 OAJ23364.1 - 0.001 18.9 1.2 1.2 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 OAJ23364.1 - 0.0017 17.9 0.0 0.54 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 OAJ23364.1 - 0.0025 17.9 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 OAJ23364.1 - 0.0027 16.9 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 OAJ23364.1 - 0.0031 16.7 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 OAJ23364.1 - 0.0048 16.6 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 OAJ23364.1 - 0.005 15.8 0.0 0.76 8.6 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase Lzipper-MIP1 PF14389.6 OAJ23364.1 - 0.0073 16.6 0.1 0.041 14.2 0.0 2.2 2 0 0 2 2 1 1 Leucine-zipper of ternary complex factor MIP1 PhoH PF02562.16 OAJ23364.1 - 0.0082 15.6 0.6 2 7.8 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein ATPase_2 PF01637.18 OAJ23364.1 - 0.0088 16.0 0.0 1.9 8.4 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea SKI PF01202.22 OAJ23364.1 - 0.019 15.1 0.1 6.8 6.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase TniB PF05621.11 OAJ23364.1 - 0.021 14.2 0.0 20 4.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein Vps4_C PF09336.10 OAJ23364.1 - 0.056 13.4 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SPX PF03105.19 OAJ23364.1 - 0.063 13.2 0.8 0.1 12.5 0.8 1.3 1 0 0 1 1 1 0 SPX domain PduV-EutP PF10662.9 OAJ23364.1 - 0.064 13.0 0.0 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 OAJ23364.1 - 0.068 13.1 0.1 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 OAJ23364.1 - 0.099 13.0 1.2 13 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 OAJ23364.1 - 0.14 12.2 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 OAJ23364.1 - 0.23 11.3 0.0 6.6 6.5 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein SOG2 PF10428.9 OAJ23364.1 - 7.2 5.7 10.5 12 4.9 10.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein HCMV_UL124 PF17609.2 OAJ23364.1 - 7.7 6.7 14.6 3.5 7.8 4.1 2.7 2 0 0 2 2 2 0 Family of unknown function Fibrillarin PF01269.17 OAJ23379.1 - 1.7e-104 347.9 0.0 2.1e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 OAJ23379.1 - 2.3e-05 24.2 0.1 3.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 OAJ23379.1 - 0.0027 17.8 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 OAJ23379.1 - 0.0032 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 OAJ23379.1 - 0.01 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Shadoo PF14999.6 OAJ23379.1 - 2 8.5 11.7 0.63 10.1 8.9 1.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Fungal_trans PF04082.18 OAJ23381.1 - 1e-25 90.3 0.0 1.8e-25 89.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ23381.1 - 1e-09 38.3 6.5 1.9e-09 37.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1769 PF08588.10 OAJ23382.1 - 2e-15 56.7 0.2 3.6e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) HSF_DNA-bind PF00447.17 OAJ23395.1 - 1.8e-30 105.4 0.6 2.6e-30 104.9 0.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding TRPM_tetra PF16519.5 OAJ23395.1 - 0.15 12.1 1.2 0.31 11.2 1.2 1.5 1 0 0 1 1 1 0 Tetramerisation domain of TRPM UPF0172 PF03665.13 OAJ23396.1 - 1.9e-43 148.7 0.0 2.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) SRF-TF PF00319.18 OAJ23397.1 - 2.4e-21 74.9 0.0 4.2e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Sporozoite_P67 PF05642.11 OAJ23418.1 - 1.2 7.1 7.4 1.5 6.8 7.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SIR4_SID PF16991.5 OAJ23418.1 - 4.5 7.3 7.2 6.5 6.8 7.2 1.2 1 0 0 1 1 1 0 Sir4 SID domain Glyco_hydro_88 PF07470.13 OAJ23441.1 - 3.7e-15 55.8 0.4 3.5e-14 52.6 0.4 2.0 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pil1 PF13805.6 OAJ23442.1 - 9.6e-49 166.2 0.0 1.8e-48 165.3 0.0 1.5 1 1 0 1 1 1 1 Eisosome component PIL1 CFTR_R PF14396.6 OAJ23442.1 - 0.09 12.3 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Lzipper-MIP1 PF14389.6 OAJ23442.1 - 4.9 7.5 7.1 33 4.9 0.3 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF747 PF05346.11 OAJ23443.1 - 2.8e-112 375.3 0.2 7.6e-99 331.2 0.5 2.2 2 0 0 2 2 2 2 Eukaryotic membrane protein family Pkinase PF00069.25 OAJ23483.1 - 3.1e-44 151.3 0.0 5.3e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23483.1 - 2.8e-25 89.1 0.0 5.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ23483.1 - 0.00014 21.3 0.1 0.00041 19.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ23483.1 - 0.00097 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Phage_GP20 PF06810.11 OAJ23483.1 - 0.0029 17.4 0.4 0.0029 17.4 0.4 2.3 2 0 0 2 2 2 1 Phage minor structural protein GP20 Filament PF00038.21 OAJ23483.1 - 0.0064 16.1 13.4 0.0064 16.1 13.4 2.2 1 1 1 2 2 2 1 Intermediate filament protein Bcr-Abl_Oligo PF09036.10 OAJ23483.1 - 0.051 13.6 0.7 0.21 11.6 0.7 2.1 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain KLRAQ PF10205.9 OAJ23483.1 - 0.057 13.7 11.8 1.1 9.5 5.5 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein TcdB_N PF12918.7 OAJ23483.1 - 0.062 13.6 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain PhoU PF01895.19 OAJ23483.1 - 0.1 13.1 6.5 1.3 9.6 0.8 2.8 2 1 1 3 3 3 0 PhoU domain RIO1 PF01163.22 OAJ23483.1 - 0.12 12.0 0.1 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 RIO1 family MAD PF05557.13 OAJ23483.1 - 0.17 10.2 23.1 0.25 9.7 23.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Sec8_exocyst PF04048.14 OAJ23483.1 - 0.22 11.4 7.3 1 9.2 0.2 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ATG16 PF08614.11 OAJ23483.1 - 0.38 11.0 28.7 0.27 11.4 6.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) OmpH PF03938.14 OAJ23483.1 - 0.4 11.0 23.8 1.4 9.3 1.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3958 PF13125.6 OAJ23483.1 - 1.4 9.2 22.5 0.18 12.0 12.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) TMF_DNA_bd PF12329.8 OAJ23483.1 - 3.3 7.8 19.8 0.55 10.3 0.6 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 OAJ23483.1 - 3.7 6.9 26.5 26 4.2 26.5 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tup_N PF08581.10 OAJ23483.1 - 3.9 7.8 16.3 3.2 8.1 6.6 3.3 2 1 1 3 3 3 0 Tup N-terminal HemX PF04375.14 OAJ23483.1 - 5.9 6.1 22.3 84 2.3 22.3 2.2 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF5595 PF18077.1 OAJ23483.1 - 6.6 6.9 7.9 1.4 9.0 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) KELK PF15796.5 OAJ23483.1 - 9.1 6.8 21.3 0.3 11.6 12.0 2.8 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HEAT PF02985.22 OAJ23504.1 - 7.7e-06 25.7 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 OAJ23504.1 - 1.3e-05 25.5 0.1 0.0015 18.9 0.0 2.9 2 1 1 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 OAJ23504.1 - 4.1e-05 23.9 0.0 0.23 11.9 0.0 2.4 2 1 0 2 2 2 2 HEAT repeats UME PF08064.13 OAJ23504.1 - 0.011 15.6 0.0 0.25 11.3 0.0 1.7 1 1 1 2 2 2 0 UME (NUC010) domain HEAT_EZ PF13513.6 OAJ23505.1 - 0.15 12.6 0.0 0.19 12.3 0.0 1.2 1 0 0 1 1 1 0 HEAT-like repeat Cytochrom_NNT PF03264.14 OAJ23507.1 - 0.037 13.7 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region zf-BED PF02892.15 OAJ23507.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger KDZ PF18758.1 OAJ23508.1 - 4.2e-47 160.6 0.0 7.4e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ23508.1 - 2e-05 24.7 0.1 6.2e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ23508.1 - 8.3e-05 22.7 0.5 0.00038 20.6 0.1 2.2 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases tRNA-synt_1 PF00133.22 OAJ23510.1 - 1.6e-05 23.4 0.0 1.8e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 OAJ23510.1 - 0.048 13.2 0.0 0.057 12.9 0.0 1.0 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 RVT_1 PF00078.27 OAJ23529.1 - 4.2e-08 33.0 0.0 9.3e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) OGG_N PF07934.12 OAJ23553.1 - 2.3e-22 79.3 0.0 8e-22 77.6 0.0 1.9 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain NmrA PF05368.13 OAJ23553.1 - 1.8e-11 44.1 0.1 0.0005 19.7 0.0 3.3 3 0 0 3 3 3 3 NmrA-like family HhH-GPD PF00730.25 OAJ23553.1 - 1.6e-10 41.3 0.0 3.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ23553.1 - 0.00059 19.6 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif NAD_binding_10 PF13460.6 OAJ23553.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Orn_Arg_deC_N PF02784.16 OAJ23570.1 - 1.4e-73 247.3 0.0 1.9e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 OAJ23570.1 - 1.2e-14 54.3 0.0 2.5e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain B12-binding PF02310.19 OAJ23570.1 - 0.05 13.6 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain zf-C2H2_jaz PF12171.8 OAJ23571.1 - 6.6e-10 39.0 1.8 1.1e-09 38.3 1.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ23571.1 - 7.2e-05 23.0 1.2 0.00011 22.4 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ23571.1 - 0.0011 19.2 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Bot1p PF12298.8 OAJ23571.1 - 0.044 14.0 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein AKAP95 PF04988.12 OAJ23571.1 - 0.098 12.9 1.1 0.16 12.2 0.9 1.4 1 1 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Spt20 PF12090.8 OAJ23572.1 - 2.1 7.9 6.8 1.3 8.6 4.0 1.9 2 0 0 2 2 2 0 Spt20 family Sulfate_transp PF00916.20 OAJ23596.1 - 5.1e-30 104.5 5.9 6.1e-30 104.2 5.9 1.0 1 0 0 1 1 1 1 Sulfate permease family SPW PF03779.14 OAJ23596.1 - 0.048 13.3 7.1 0.42 10.2 0.2 2.9 2 0 0 2 2 2 0 SPW repeat UBA2_C PF16195.5 OAJ23597.1 - 0.084 13.6 0.3 0.084 13.6 0.3 1.7 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Corona_NS3b PF03053.14 OAJ23620.1 - 0.088 12.6 0.1 0.088 12.6 0.1 2.0 2 0 0 2 2 2 0 ORF3b coronavirus protein Sec3_C PF09763.9 OAJ23621.1 - 0.016 13.6 4.1 0.026 12.9 4.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4335 PF14233.6 OAJ23621.1 - 0.03 14.2 3.7 0.053 13.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) DUF3496 PF12001.8 OAJ23621.1 - 0.17 12.3 2.3 0.26 11.7 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) T6PP_N PF18572.1 OAJ23621.1 - 0.53 10.2 4.5 11 6.0 0.4 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Cys_Met_Meta_PP PF01053.20 OAJ23622.1 - 3.6e-53 180.5 0.0 1.6e-46 158.6 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 OAJ23622.1 - 0.067 12.1 0.1 0.14 11.1 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ23622.1 - 0.099 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II EPSP_synthase PF00275.20 OAJ23644.1 - 0.0025 16.6 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FliO PF04347.13 OAJ23644.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.6 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO MULE PF10551.9 OAJ23645.1 - 2.3e-08 34.3 0.0 9.3e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.15 OAJ23645.1 - 6.5e-05 23.5 0.3 0.00019 22.0 0.0 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain SWIM PF04434.17 OAJ23645.1 - 0.00041 19.9 0.2 0.0009 18.9 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF5575 PF17738.1 OAJ23645.1 - 0.0083 15.2 0.0 0.23 10.4 0.0 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5575) rve PF00665.26 OAJ23645.1 - 0.027 14.7 0.0 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Cnd2 PF05786.14 OAJ23645.1 - 0.12 11.0 3.2 0.21 10.2 0.0 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 Phage_integrase PF00589.22 OAJ23662.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Glyco_hydro_85 PF03644.13 OAJ23663.1 - 3.6e-09 36.5 0.2 7e-09 35.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 85 TPR_12 PF13424.6 OAJ23689.1 - 0.16 12.3 28.4 1.3 9.4 0.1 7.9 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23689.1 - 0.2 12.4 3.2 11 6.9 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23689.1 - 0.73 10.1 13.6 8.8 6.7 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ23689.1 - 5.8 6.9 18.5 3.5 7.6 0.2 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat PhoLip_ATPase_C PF16212.5 OAJ23690.1 - 1e-72 244.9 30.2 1e-72 244.9 30.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ23690.1 - 4.4e-21 74.3 0.8 4.4e-21 74.3 0.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ23690.1 - 1.5e-12 48.3 0.9 6.2e-05 23.4 0.7 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ23690.1 - 1.4e-11 44.3 0.0 3.1e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 OAJ23690.1 - 4.8e-06 26.2 0.0 4.8e-06 26.2 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ23690.1 - 0.0026 17.5 0.1 0.0073 16.1 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PBP1_TM PF14812.6 OAJ23690.1 - 1.2 9.6 3.8 5.1 7.5 3.8 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exo_endo_phos PF03372.23 OAJ23710.1 - 1.1e-19 70.9 0.0 1.1e-19 70.9 0.0 3.2 3 2 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 OAJ23710.1 - 7.8e-10 38.9 3.1 0.00044 20.6 0.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ23710.1 - 1.6e-08 34.2 5.5 2.1e-05 24.2 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat CENP-B_dimeris PF09026.10 OAJ23710.1 - 3.8 8.0 7.7 0.18 12.2 1.5 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop53 PF07767.11 OAJ23710.1 - 5.1 6.4 13.3 11 5.3 13.3 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Steroid_dh PF02544.16 OAJ23711.1 - 6.1e-23 81.5 1.9 1.1e-07 31.9 0.0 4.2 3 1 1 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 OAJ23711.1 - 0.008 15.7 0.1 0.02 14.4 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 OAJ23712.1 - 1.5e-39 136.0 0.0 1.1e-26 93.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ23712.1 - 3.2e-16 59.4 0.0 7.2e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ23712.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pam16 PF03656.13 OAJ23713.1 - 5.7e-11 42.5 11.4 2.2e-06 27.7 11.4 4.0 1 1 0 1 1 1 1 Pam16 Dehydrin PF00257.19 OAJ23713.1 - 0.59 10.7 5.2 5.1 7.6 0.3 2.1 2 0 0 2 2 2 0 Dehydrin WPP PF13943.6 OAJ23713.1 - 2.1 8.8 8.6 3.1 8.3 0.7 2.7 2 1 1 3 3 3 0 WPP domain Macoilin PF09726.9 OAJ23733.1 - 0.64 8.5 20.4 0.16 10.5 12.6 2.2 2 0 0 2 2 2 0 Macoilin family Mpp10 PF04006.12 OAJ23734.1 - 1.1e-75 255.3 0.1 1.4e-75 255.0 0.1 1.0 1 0 0 1 1 1 1 Mpp10 protein Peptidase_C1_2 PF03051.15 OAJ23735.1 - 7e-135 450.2 0.0 2.1e-133 445.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 OAJ23735.1 - 8.2e-06 26.1 0.0 0.00069 19.8 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease BRO1 PF03097.18 OAJ23754.1 - 0.00011 21.1 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain UPF0020 PF01170.18 OAJ23755.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 KDZ PF18758.1 OAJ23756.1 - 3e-53 180.7 0.0 5.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ23756.1 - 1.3e-05 25.3 0.0 2.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ23756.1 - 3.3e-05 24.0 0.0 7.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 OAJ23756.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases DEAD PF00270.29 OAJ23757.1 - 0.00043 20.1 0.0 0.00049 19.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.25 OAJ23758.1 - 0.00014 21.7 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Aldedh PF00171.22 OAJ23778.1 - 3.2e-126 421.6 0.1 4.3e-126 421.1 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 OAJ23779.1 - 1.5e-05 25.7 4.7 0.012 16.4 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40 PF00400.32 OAJ23780.1 - 4.8e-55 182.3 21.0 2.5e-08 34.4 0.6 11.7 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 OAJ23780.1 - 1.3e-41 141.9 0.0 4.5e-41 140.1 0.0 1.9 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 OAJ23780.1 - 7.3e-13 48.6 0.0 0.054 13.8 0.0 8.0 7 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ23780.1 - 1.6e-07 30.3 0.1 0.65 8.6 0.1 5.3 5 1 0 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ23780.1 - 7.8e-05 21.6 0.0 0.027 13.2 0.0 4.0 4 1 1 5 5 5 1 Nup133 N terminal like Ge1_WD40 PF16529.5 OAJ23780.1 - 0.0045 16.0 0.0 2 7.3 0.0 4.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ZirS_C PF16583.5 OAJ23780.1 - 0.045 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain PD40 PF07676.12 OAJ23780.1 - 0.069 13.1 0.0 19 5.3 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Chorion_2 PF03964.15 OAJ23780.1 - 8.9 7.2 16.4 3.9 8.4 5.3 3.2 2 0 0 2 2 2 0 Chorion family 2 Metallophos PF00149.28 OAJ23781.1 - 8.3e-35 121.1 0.2 1e-34 120.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 OAJ23798.1 - 3.2e-18 65.3 0.0 4.3e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRC1 PF09444.10 OAJ23799.1 - 3.3e-19 69.8 24.4 3.3e-19 69.8 24.4 6.0 6 1 0 6 6 6 1 MRC1-like domain GP38 PF05268.11 OAJ23799.1 - 0.79 9.3 10.9 1.3 8.6 10.9 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 Jnk-SapK_ap_N PF09744.9 OAJ23800.1 - 0.0089 16.3 0.5 0.011 16.0 0.5 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 ZapB PF06005.12 OAJ23800.1 - 0.15 12.5 4.4 0.21 12.1 4.4 1.1 1 0 0 1 1 1 0 Cell division protein ZapB LapA_dom PF06305.11 OAJ23800.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain IBN_N PF03810.19 OAJ23817.1 - 8.6e-07 28.8 0.0 3.5e-05 23.6 0.0 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAJ23817.1 - 0.045 13.8 0.1 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 Exportin 1-like protein Arf PF00025.21 OAJ23818.1 - 4.6e-36 123.9 0.0 1.7e-24 86.2 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 OAJ23818.1 - 1.9e-13 50.7 0.0 3.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ23818.1 - 4.6e-13 49.1 0.0 2.1e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 OAJ23818.1 - 3.5e-08 33.1 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ23818.1 - 3.5e-05 23.3 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ23818.1 - 7.8e-05 22.0 0.2 0.00024 20.4 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ23818.1 - 0.00015 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ23818.1 - 0.11 12.5 0.3 0.22 11.6 0.3 1.5 1 1 0 1 1 1 0 Dynamin family DPBB_1 PF03330.18 OAJ23819.1 - 0.0001 22.5 0.2 0.00059 20.1 0.2 2.2 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ23819.1 - 0.018 14.9 0.1 0.024 14.5 0.1 1.2 1 0 0 1 1 1 0 Barwin family DUF5061 PF16587.5 OAJ23819.1 - 0.047 13.7 0.1 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 17 kDa common-antigen outer membrane protein DUF1962 PF09227.10 OAJ23819.1 - 0.12 12.8 0.6 0.18 12.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) FAM176 PF14851.6 OAJ23820.1 - 5.2 6.7 7.5 14 5.4 3.8 2.4 2 0 0 2 2 2 0 FAM176 family PUF PF00806.19 OAJ23842.1 - 3.7e-59 193.2 2.8 4.9e-10 38.5 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Acyl-CoA_dh_N PF02771.16 OAJ23842.1 - 0.032 14.9 0.0 14 6.3 0.0 3.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Spt20 PF12090.8 OAJ23842.1 - 0.5 9.9 5.7 1 8.9 5.7 1.5 1 0 0 1 1 1 0 Spt20 family Fer2_3 PF13085.6 OAJ23843.1 - 2.3e-32 111.2 0.0 3.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 OAJ23843.1 - 5.3e-09 36.5 6.1 5.3e-09 36.5 6.1 2.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ23843.1 - 5.4e-07 30.0 7.4 5.4e-07 30.0 7.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAJ23843.1 - 8.7e-07 29.0 3.6 8.7e-07 29.0 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 OAJ23843.1 - 0.013 15.4 1.4 0.013 15.4 1.4 2.2 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 OAJ23843.1 - 0.016 15.8 6.3 0.016 15.8 6.3 2.6 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 OAJ23843.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAJ23843.1 - 2.4 8.4 14.6 0.41 10.8 8.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Tetraspanin PF00335.20 OAJ23844.1 - 5.2e-14 52.5 6.5 6.9e-14 52.1 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family Glyco_hydro_18 PF00704.28 OAJ23865.1 - 5.3e-44 151.2 0.0 6.6e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 IMP_cyclohyd PF07826.11 OAJ23868.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein S4 PF01479.25 OAJ23888.1 - 3e-11 42.8 0.0 5.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 OAJ23888.1 - 4e-10 40.5 0.1 5.3e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Peptidase_M24 PF00557.24 OAJ23889.1 - 3e-50 170.8 0.0 4.5e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 OAJ23889.1 - 5.1e-40 136.0 0.0 1.3e-39 134.8 0.0 1.6 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 OAJ23889.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Creatinase_N_2 PF16189.5 OAJ23890.1 - 5.4e-44 150.1 0.0 2.8e-43 147.8 0.0 2.1 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 OAJ23890.1 - 1.6e-42 145.6 0.0 2.2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 OAJ23890.1 - 4.6e-19 68.2 0.0 1.1e-17 63.8 0.0 2.7 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 OAJ23890.1 - 6.9e-17 62.3 0.0 3.1e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Lipase_3 PF01764.25 OAJ23890.1 - 0.072 12.9 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Xan_ur_permease PF00860.20 OAJ23891.1 - 5.9e-54 183.2 30.4 1.5e-52 178.7 30.4 2.1 1 1 0 1 1 1 1 Permease family RNA_pol_A_bac PF01000.26 OAJ23892.1 - 1.2e-26 93.3 0.0 2.5e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 OAJ23892.1 - 2.5e-22 78.1 0.0 3.2e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 OAJ23892.1 - 0.021 14.5 0.0 0.086 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF22 Formyl_trans_N PF00551.19 OAJ23911.1 - 1e-33 116.6 0.0 4.9e-18 65.5 0.2 2.0 1 1 1 2 2 2 2 Formyl transferase RhoGEF PF00621.20 OAJ23912.1 - 9.2e-17 61.9 0.1 2.4e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Chromo_shadow PF01393.19 OAJ23912.1 - 7e-12 45.3 0.0 2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 OAJ23912.1 - 1.2e-06 28.3 3.4 1.2e-06 28.3 3.4 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SWIRM-assoc_2 PF16496.5 OAJ23912.1 - 0.26 10.1 6.3 0.51 9.2 6.3 1.4 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Ribosomal_L7Ae PF01248.26 OAJ23913.1 - 9.6e-22 76.5 0.3 1.5e-21 76.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ23913.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 ATPase_2 PF01637.18 OAJ23913.1 - 0.077 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Transposase_21 PF02992.14 OAJ23933.1 - 5.2e-09 35.7 0.0 8.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Prok-RING_4 PF14447.6 OAJ23933.1 - 0.62 10.0 6.7 0.2 11.5 2.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PspB PF06667.12 OAJ23934.1 - 0.0058 16.7 1.1 0.0058 16.7 1.1 2.9 2 1 1 3 3 3 1 Phage shock protein B DivIC PF04977.15 OAJ23934.1 - 0.025 14.4 3.0 0.025 14.4 3.0 2.9 3 0 0 3 3 3 0 Septum formation initiator Peptidase_S46 PF10459.9 OAJ23934.1 - 0.1 11.2 16.3 0.14 10.8 16.3 1.0 1 0 0 1 1 1 0 Peptidase S46 CALCOCO1 PF07888.11 OAJ23934.1 - 0.2 10.5 32.5 0.12 11.2 3.7 2.1 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 OAJ23934.1 - 1.4 9.5 13.6 1 10.0 0.4 3.6 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Paralemmin PF03285.15 OAJ23934.1 - 1.6 8.2 16.8 0.11 12.1 9.3 2.3 1 1 2 3 3 3 0 Paralemmin FlaC_arch PF05377.11 OAJ23934.1 - 2 8.9 8.8 10 6.6 0.5 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FlxA PF14282.6 OAJ23934.1 - 3.9 7.5 12.5 19 5.3 5.3 2.4 1 1 1 2 2 2 0 FlxA-like protein TSC22 PF01166.18 OAJ23934.1 - 4.4 7.7 9.8 1.6 9.1 0.5 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family SOG2 PF10428.9 OAJ23935.1 - 0.52 9.4 3.0 6.8 5.8 1.4 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein TGF_beta_GS PF08515.12 OAJ23936.1 - 0.17 11.4 0.4 0.17 11.4 0.4 2.4 2 1 0 2 2 2 0 Transforming growth factor beta type I GS-motif Serglycin PF04360.12 OAJ23936.1 - 5.5 6.9 11.2 1.5 8.7 2.8 2.1 1 1 1 2 2 2 0 Serglycin Flavoprotein PF02441.19 OAJ23956.1 - 1.2e-49 168.1 0.0 1.4e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein TPR_11 PF13414.6 OAJ23957.1 - 2.8e-19 68.5 2.3 6.6e-05 22.5 0.0 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.28 OAJ23957.1 - 1.3e-18 65.9 2.5 1.9e-06 27.4 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ23957.1 - 6.6e-18 63.3 3.5 1.8e-05 24.5 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ23957.1 - 3.6e-14 53.1 5.4 1.3e-08 35.3 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ23957.1 - 9.7e-13 48.4 0.3 1.6e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ23957.1 - 1.8e-12 46.4 3.5 0.0088 16.2 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ23957.1 - 4.3e-09 36.1 0.1 0.18 12.3 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ23957.1 - 4.5e-09 36.4 0.7 0.00034 21.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ23957.1 - 4.7e-09 36.3 12.3 0.39 11.6 0.7 6.0 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ23957.1 - 5.7e-09 36.1 6.0 0.026 14.8 0.6 3.8 2 2 2 4 4 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ23957.1 - 0.00015 21.9 1.1 0.0015 18.7 0.0 2.6 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ23957.1 - 0.00015 21.5 0.8 1.5 9.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ23957.1 - 0.00016 21.8 0.0 0.081 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 OAJ23957.1 - 0.00029 20.6 2.0 0.18 11.5 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 OAJ23957.1 - 0.0031 16.8 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ23957.1 - 0.0039 17.0 1.7 2.4 8.1 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 OAJ23957.1 - 0.018 15.3 1.2 0.069 13.4 0.7 2.1 2 0 0 2 2 2 0 Tetratrico peptide repeat YfiO PF13525.6 OAJ23957.1 - 0.042 13.6 0.2 0.092 12.4 0.0 1.6 2 0 0 2 2 2 0 Outer membrane lipoprotein HSCB_C PF07743.13 OAJ23957.1 - 0.046 14.2 7.1 0.049 14.1 4.3 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain SPATA24 PF15175.6 OAJ23957.1 - 0.38 10.6 3.3 0.23 11.3 1.1 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 T7SS_ESX_EspC PF10824.8 OAJ23957.1 - 0.92 10.0 7.4 0.16 12.5 1.1 2.5 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm HemY_N PF07219.13 OAJ23957.1 - 5.6 7.2 7.7 5 7.4 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus RTC4 PF14474.6 OAJ23958.1 - 5.8e-12 45.8 0.0 1.4e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 RTC4-like domain DIM PF08194.12 OAJ23959.1 - 0.15 12.3 0.2 0.31 11.3 0.2 1.5 1 0 0 1 1 1 0 DIM protein VanZ PF04892.12 OAJ23977.1 - 3.3e-07 31.0 1.9 4.9e-07 30.5 1.9 1.2 1 0 0 1 1 1 1 VanZ like family Serglycin PF04360.12 OAJ23977.1 - 1.1 9.2 4.9 58 3.6 5.1 2.5 2 0 0 2 2 2 0 Serglycin HECT PF00632.25 OAJ23978.1 - 8.1e-97 324.4 0.0 1.1e-96 324.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 OAJ23978.1 - 9.5e-35 118.4 13.1 1.1e-11 44.5 2.4 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 OAJ23978.1 - 3.7e-19 68.9 0.0 1e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Complex1_LYR PF05347.15 OAJ23979.1 - 6.5e-05 22.9 0.2 0.00012 22.1 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ23979.1 - 0.02 15.7 0.2 0.031 15.0 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Tctex-1 PF03645.13 OAJ23980.1 - 8.8e-11 42.0 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Totivirus_coat PF05518.11 OAJ23980.1 - 7.4 4.5 11.5 9 4.2 11.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein RCR PF12273.8 OAJ23981.1 - 3.1e-05 24.6 5.3 7e-05 23.5 5.3 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 OAJ23981.1 - 8.5e-05 22.5 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 DUF1180 PF06679.12 OAJ23981.1 - 0.0058 17.1 1.1 0.0058 17.1 1.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1180) GRP PF07172.11 OAJ23981.1 - 0.0093 16.6 2.2 0.02 15.6 2.2 1.5 1 1 0 1 1 1 1 Glycine rich protein family EphA2_TM PF14575.6 OAJ23981.1 - 0.0094 16.8 0.5 0.02 15.8 0.6 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.11 OAJ23981.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 TMEM9 Rax2 PF12768.7 OAJ23981.1 - 0.034 13.6 0.2 0.049 13.1 0.2 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SIT PF15330.6 OAJ23981.1 - 0.036 14.5 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Mid2 PF04478.12 OAJ23981.1 - 0.04 13.8 0.9 0.063 13.1 0.4 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4834 PF16118.5 OAJ23981.1 - 0.059 14.3 1.1 0.13 13.2 1.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 OAJ23981.1 - 0.07 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 OAJ23981.1 - 0.088 12.7 0.2 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 TMEM154 protein family LapA_dom PF06305.11 OAJ23981.1 - 0.35 10.7 6.4 0.54 10.1 4.1 2.0 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Rhabdo_glycop PF00974.18 OAJ23981.1 - 0.7 8.3 4.4 0.3 9.5 0.7 1.9 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Retrotran_gag_2 PF14223.6 OAJ24001.1 - 9.5e-12 44.8 0.1 1.1e-11 44.5 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2138 PF09909.9 OAJ24002.1 - 0.053 11.8 0.1 0.066 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Dynactin_p22 PF07426.11 OAJ24002.1 - 0.055 13.3 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Pkinase PF00069.25 OAJ24028.1 - 3.7e-72 242.9 0.0 5e-72 242.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24028.1 - 6.2e-36 124.0 0.0 9.2e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 OAJ24028.1 - 1.4e-18 67.4 0.0 1.1e-16 61.4 0.0 2.7 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 OAJ24028.1 - 3.3e-07 29.9 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 OAJ24028.1 - 8.6e-05 22.6 1.2 0.00012 22.1 0.3 1.7 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) AAA_lid_3 PF17862.1 OAJ24028.1 - 0.015 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 AAA+ lid domain RIO1 PF01163.22 OAJ24028.1 - 0.03 13.9 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 OAJ24028.1 - 0.17 10.8 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PLA2_B PF01735.18 OAJ24029.1 - 9.5e-14 50.7 0.0 1.2e-06 27.2 0.0 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain G-alpha PF00503.20 OAJ24044.1 - 2.8e-74 250.4 0.0 1e-55 189.3 0.0 2.8 2 1 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 OAJ24044.1 - 7e-10 38.6 0.0 1.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ24044.1 - 0.0016 18.8 0.1 0.032 14.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ24044.1 - 0.0045 17.3 0.0 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ24044.1 - 0.0065 16.2 0.0 0.093 12.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAJ24044.1 - 0.0073 16.8 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 OAJ24044.1 - 0.025 13.9 0.0 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 OAJ24044.1 - 0.044 13.7 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 OAJ24044.1 - 0.065 13.5 0.0 1.4 9.2 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 OAJ24044.1 - 0.074 12.6 0.0 1 8.9 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 OAJ24044.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 OAJ24045.1 - 1.6e-22 79.4 0.3 1.3e-14 54.0 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ24045.1 - 1.5e-21 76.9 0.0 2.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ24045.1 - 1.2e-15 57.7 0.0 3.7e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ24045.1 - 1.3e-15 57.3 0.2 2.2e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ24045.1 - 3.8e-08 33.5 0.0 9.1e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 OAJ24045.1 - 8.5e-05 23.1 0.0 0.00026 21.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ24045.1 - 0.03 14.9 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DRIM PF07539.12 OAJ24064.1 - 3.2e-159 531.2 4.5 3.2e-159 531.2 4.5 3.4 4 1 0 4 4 4 1 Down-regulated in metastasis ParcG PF10274.9 OAJ24064.1 - 0.041 14.0 0.5 0.88 9.7 0.1 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein Condensin2nSMC PF12422.8 OAJ24064.1 - 0.099 12.8 0.4 0.58 10.3 0.4 2.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Telomere_reg-2 PF10193.9 OAJ24064.1 - 0.54 10.7 3.0 0.94 9.9 0.2 3.1 3 0 0 3 3 3 0 Telomere length regulation protein Nop14 PF04147.12 OAJ24064.1 - 5 5.2 25.2 1.8 6.7 13.4 2.4 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 OAJ24064.1 - 9.8 4.3 24.5 5.9 5.0 14.2 2.5 2 0 0 2 2 2 0 CDC45-like protein CDC45 PF02724.14 OAJ24084.1 - 0.011 14.1 4.2 0.014 13.8 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2106 PF09879.9 OAJ24105.1 - 0.082 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Flavin_Reduct PF01613.18 OAJ24106.1 - 2e-22 79.9 0.0 2.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain BCS1_N PF08740.11 OAJ24107.1 - 2.2e-49 168.0 0.2 3.1e-49 167.5 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 OAJ24107.1 - 7.2e-17 62.0 0.0 2.3e-16 60.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ24107.1 - 0.00025 20.3 0.0 0.00057 19.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 OAJ24107.1 - 0.00071 20.0 1.4 0.0083 16.5 0.8 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 OAJ24107.1 - 0.0031 17.2 0.1 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 OAJ24107.1 - 0.0079 15.8 0.1 0.13 11.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 OAJ24107.1 - 0.031 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 OAJ24107.1 - 0.039 14.0 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 OAJ24107.1 - 0.046 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 OAJ24107.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ24107.1 - 0.15 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OAJ24123.1 - 7.4e-31 107.3 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ24123.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ24123.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 OAJ24123.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 OAJ24123.1 - 0.033 14.2 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 OAJ24123.1 - 0.052 13.0 0.0 0.27 10.7 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ24123.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 OAJ24124.1 - 5.8e-10 38.8 0.0 0.00072 19.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cuticle_1 PF08140.11 OAJ24124.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Crustacean cuticle protein repeat CDH-cyt PF16010.5 OAJ24125.1 - 6.9e-13 48.7 5.4 1.1e-12 48.0 5.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ24125.1 - 2.1e-08 34.4 9.9 4.2e-08 33.4 9.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ24125.1 - 4.5e-05 23.7 1.2 0.0001 22.5 0.9 1.8 1 1 1 2 2 2 1 DOMON domain DUF2427 PF10348.9 OAJ24125.1 - 0.055 13.3 4.5 0.23 11.3 4.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Thioredoxin PF00085.20 OAJ24126.1 - 2.4e-09 37.1 0.0 2.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HLH PF00010.26 OAJ24149.1 - 0.04 13.9 0.8 0.08 12.9 0.8 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Sec66 PF09802.9 OAJ24149.1 - 0.22 11.1 0.7 0.34 10.5 0.7 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 AMP-binding PF00501.28 OAJ24150.1 - 1.1e-68 231.8 0.0 1.6e-68 231.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 OAJ24150.1 - 0.0018 17.9 9.7 2.2 8.1 0.7 6.1 7 1 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 OAJ24150.1 - 0.0035 17.7 0.0 0.0089 16.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site STAG PF08514.11 OAJ24178.1 - 3.7e-32 110.6 1.5 1.1e-31 109.1 1.5 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 OAJ24178.1 - 0.065 13.5 0.2 12 6.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat WD40 PF00400.32 OAJ24179.1 - 1.3e-39 133.4 26.8 3.7e-08 33.9 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24179.1 - 8.2e-16 58.1 2.1 0.00012 22.4 0.1 6.0 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ24179.1 - 8.8e-14 51.8 0.9 4.9e-08 33.1 0.1 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 OAJ24179.1 - 0.0001 21.4 3.3 0.021 13.8 0.3 3.5 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 OAJ24179.1 - 0.00026 20.4 0.0 0.05 12.9 0.0 2.7 2 1 0 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 OAJ24179.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 1 0 1 1 1 0 Coatomer WD associated region Polysacc_deac_1 PF01522.21 OAJ24200.1 - 7.6e-27 93.7 0.0 1.2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase cobW PF02492.19 OAJ24220.1 - 3.3e-32 111.5 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 OAJ24220.1 - 0.00014 20.9 2.4 0.00093 18.3 2.4 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ24220.1 - 0.02 15.5 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 OAJ24220.1 - 0.024 14.7 0.0 0.21 11.7 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ24220.1 - 0.042 14.2 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 OAJ24220.1 - 0.046 13.2 0.0 5.8 6.4 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CbtA PF09490.10 OAJ24220.1 - 0.051 13.3 0.2 0.077 12.7 0.2 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) T2SSE PF00437.20 OAJ24220.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 OAJ24220.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 OAJ24220.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SelP_N PF04592.14 OAJ24220.1 - 0.46 9.9 13.3 0.67 9.3 13.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ufd2P_core PF10408.9 OAJ24221.1 - 1.5e-198 661.4 0.1 1.9e-198 661.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 OAJ24221.1 - 4.9e-26 90.7 0.4 1.6e-25 89.1 0.4 2.0 1 0 0 1 1 1 1 U-box domain AP1AR PF15745.5 OAJ24221.1 - 0.0049 16.6 0.7 0.054 13.1 0.0 2.5 2 0 0 2 2 2 1 AP-1 complex-associated regulatory protein Ten1_2 PF15490.6 OAJ24223.1 - 5.6e-06 26.1 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit RNA_Me_trans PF04252.13 OAJ24224.1 - 2.9e-52 177.2 0.0 3.5e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase adh_short PF00106.25 OAJ24248.1 - 2.4e-87 291.4 18.0 9.4e-44 149.2 5.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ24248.1 - 4.2e-70 235.9 21.3 4.7e-35 121.2 7.1 2.7 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 OAJ24248.1 - 9.9e-30 102.6 0.0 2.2e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 OAJ24248.1 - 3.1e-28 98.9 10.8 7e-14 52.1 2.3 2.2 2 0 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 OAJ24248.1 - 3e-06 26.7 2.1 0.034 13.5 0.1 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MaoC_dehydrat_N PF13452.6 OAJ24248.1 - 7.8e-05 22.8 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 OAJ24248.1 - 0.00017 20.9 0.6 0.12 11.7 0.3 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 OAJ24248.1 - 0.00081 19.3 8.5 0.047 13.6 1.4 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF543 PF04418.12 OAJ24248.1 - 0.097 12.7 4.5 1.4 8.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) AdoHcyase_NAD PF00670.21 OAJ24248.1 - 0.4 10.7 5.0 0.63 10.1 0.4 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PglL_A PF15864.5 OAJ24248.1 - 2.3 8.0 8.2 10 6.0 1.0 2.7 2 0 0 2 2 2 0 Protein glycosylation ligase Spt5_N PF11942.8 OAJ24249.1 - 3.4 8.7 7.9 1.1 10.2 2.0 2.9 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Bd3614_N PF14442.6 OAJ24249.1 - 7.9 6.9 6.5 0.75 10.1 0.3 2.5 3 0 0 3 3 3 0 Bd3614-like deaminase N-terminal Pkinase_Tyr PF07714.17 OAJ24250.1 - 6e-47 160.1 0.0 8.1e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 OAJ24250.1 - 2.5e-45 154.9 0.0 3.8e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 OAJ24250.1 - 0.0073 15.3 0.1 0.023 13.7 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ24250.1 - 0.051 12.3 4.1 0.081 11.7 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase DUF4637 PF15470.6 OAJ24250.1 - 0.89 9.3 18.8 2.3 7.9 6.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4637) TLP-20 PF06088.11 OAJ24250.1 - 5.3 6.9 8.3 0.27 11.1 0.3 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) zf-RanBP PF00641.18 OAJ24277.1 - 1.1e-11 43.8 10.8 4.8e-07 29.0 0.9 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others W2 PF02020.18 OAJ24298.1 - 2.5e-18 66.0 0.2 2.5e-18 66.0 0.2 2.4 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon FAD_binding_1 PF00667.20 OAJ24299.1 - 1.4e-56 191.6 0.0 2.2e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 OAJ24299.1 - 4.6e-32 111.2 0.1 8.6e-32 110.3 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 OAJ24299.1 - 1.3e-20 74.1 0.0 6.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain zf-Nse PF11789.8 OAJ24301.1 - 2.2e-13 49.8 0.1 4.1e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3246 PF11596.8 OAJ24301.1 - 0.00051 19.5 5.6 0.001 18.6 5.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) U-box PF04564.15 OAJ24301.1 - 0.0068 16.6 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain SIL1 PF16782.5 OAJ24301.1 - 0.043 13.0 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 DUF5065 PF16723.5 OAJ24301.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) NOA36 PF06524.12 OAJ24301.1 - 1.6 7.9 0.0 1.6 7.9 0.0 2.7 2 2 0 2 2 2 0 NOA36 protein Pkinase PF00069.25 OAJ24325.1 - 1.4e-18 67.2 0.0 2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24325.1 - 4.8e-11 42.4 0.0 6.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ24325.1 - 0.0027 17.1 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_viral_C PF00336.18 OAJ24325.1 - 0.0067 15.9 0.0 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAJ24325.1 - 0.0099 15.7 0.1 0.026 14.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Haspin_kinase PF12330.8 OAJ24325.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Fez1 PF06818.15 OAJ24326.1 - 0.2 12.1 43.0 0.33 11.4 4.1 3.2 1 1 2 3 3 3 0 Fez1 BST2 PF16716.5 OAJ24326.1 - 2.8 8.6 38.8 0.44 11.2 1.4 4.5 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 PspA_IM30 PF04012.12 OAJ24326.1 - 9 5.8 51.0 2.2 7.8 8.0 3.4 3 1 1 4 4 4 0 PspA/IM30 family Dimer_Tnp_hAT PF05699.14 OAJ24350.1 - 7e-21 73.8 0.1 1.4e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Hydrolase_4 PF12146.8 OAJ24374.1 - 0.0002 20.7 0.1 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Methyltransf_28 PF02636.17 OAJ24374.1 - 0.063 12.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lipase_3 PF01764.25 OAJ24374.1 - 0.089 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) ACBP PF00887.19 OAJ24375.1 - 9.6e-31 105.8 0.2 1.3e-30 105.4 0.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Exonuc_X-T_C PF08411.10 OAJ24375.1 - 0.1 11.7 0.4 0.14 11.3 0.4 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal RSN1_7TM PF02714.15 OAJ24376.1 - 1.7e-74 250.6 21.2 2.8e-74 249.9 21.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ24376.1 - 1e-39 136.5 0.2 1.6e-39 136.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ24376.1 - 1.6e-34 118.9 2.2 1.6e-34 118.9 2.2 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAJ24376.1 - 1.5e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Dicistro_VP4 PF11492.8 OAJ24376.1 - 0.04 13.9 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 zf-U1 PF06220.12 OAJ24400.1 - 4.4e-05 23.2 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 U1 zinc finger BTB PF00651.31 OAJ24401.1 - 3e-12 46.7 0.1 1.6e-05 25.1 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain MATH PF00917.26 OAJ24401.1 - 0.13 12.4 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 MATH domain 2OG-FeII_Oxy_3 PF13640.6 OAJ24402.1 - 0.00013 22.7 0.0 0.00026 21.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vps5 PF09325.10 OAJ24403.1 - 1.1e-59 201.9 4.8 1.1e-59 201.9 4.8 3.7 3 1 1 4 4 4 1 Vps5 C terminal like RmlD_sub_bind PF04321.17 OAJ24403.1 - 5.5e-49 166.8 0.0 5.5e-49 166.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 OAJ24403.1 - 1.6e-21 76.9 0.0 3.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PX PF00787.24 OAJ24403.1 - 2e-21 76.1 0.0 6.9e-21 74.3 0.0 1.9 1 0 0 1 1 1 1 PX domain GDP_Man_Dehyd PF16363.5 OAJ24403.1 - 3.3e-08 33.3 0.0 3.3e-08 33.3 0.0 3.3 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAJ24403.1 - 8.1e-06 25.2 0.3 0.00015 21.0 0.0 2.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 OAJ24403.1 - 0.00025 20.3 0.0 0.00025 20.3 0.0 3.4 3 0 0 3 3 3 1 Male sterility protein Pep3_Vps18 PF05131.14 OAJ24427.1 - 1.7e-46 157.8 0.0 4.7e-46 156.3 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 OAJ24427.1 - 3.4e-08 33.5 8.4 5.9e-07 29.5 0.3 2.8 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 OAJ24427.1 - 0.00016 21.2 0.7 0.00053 19.5 0.7 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 OAJ24427.1 - 0.00074 19.5 2.4 0.00074 19.5 2.4 1.9 2 0 0 2 2 2 1 Zinc-finger zf-RING_5 PF14634.6 OAJ24427.1 - 0.0012 18.7 1.0 0.003 17.5 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ24427.1 - 0.034 14.0 1.9 0.089 12.7 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 OAJ24427.1 - 0.059 13.8 0.6 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 OAJ24427.1 - 0.079 13.3 3.9 0.048 14.0 1.2 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2175 PF09943.9 OAJ24427.1 - 0.2 12.0 1.9 0.89 9.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DNA_pol_phi PF04931.13 OAJ24428.1 - 0.0057 14.8 21.0 0.0076 14.4 21.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi YL1 PF05764.13 OAJ24428.1 - 0.012 15.8 34.0 0.023 14.8 34.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein DUF1822 PF08852.11 OAJ24428.1 - 0.046 12.8 0.0 0.046 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) CDC45 PF02724.14 OAJ24428.1 - 0.37 9.0 25.9 0.6 8.3 25.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 OAJ24428.1 - 0.6 8.5 19.8 0.66 8.4 19.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Nop53 PF07767.11 OAJ24428.1 - 0.6 9.4 40.7 0.94 8.8 40.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Zip PF02535.22 OAJ24428.1 - 3.2 6.9 6.7 4.4 6.4 6.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.11 OAJ24428.1 - 4.1 5.4 12.0 2.3 6.2 10.0 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Raftlin PF15250.6 OAJ24428.1 - 4.7 5.8 13.1 5 5.8 12.1 1.4 1 1 0 1 1 1 0 Raftlin eIF3_subunit PF08597.10 OAJ24428.1 - 7.1 6.5 38.7 13 5.6 38.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SLC12 PF03522.15 OAJ24428.1 - 9.1 5.2 10.1 13 4.7 10.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Mcm10 PF09332.11 OAJ24429.1 - 0.0083 15.6 2.2 0.013 15.0 2.2 1.2 1 0 0 1 1 1 1 Mcm10 replication factor Borrelia_P83 PF05262.11 OAJ24429.1 - 0.014 13.9 3.1 0.017 13.6 3.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Uds1 PF15456.6 OAJ24429.1 - 0.089 13.0 5.6 0.15 12.2 5.6 1.3 1 0 0 1 1 1 0 Up-regulated During Septation WDCP PF15390.6 OAJ24429.1 - 0.17 10.2 0.4 0.25 9.7 0.4 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Tho2 PF11262.8 OAJ24429.1 - 0.19 10.9 3.8 0.28 10.3 3.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1764 PF08576.10 OAJ24429.1 - 0.21 12.5 4.5 0.56 11.1 4.5 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Casc1_N PF15927.5 OAJ24429.1 - 0.21 11.2 10.0 0.34 10.6 10.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3584 PF12128.8 OAJ24429.1 - 0.3 8.6 5.6 0.42 8.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 OAJ24429.1 - 0.32 10.2 1.6 0.45 9.7 1.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Med30 PF11315.8 OAJ24429.1 - 0.34 11.1 3.7 0.58 10.3 3.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 HemX PF04375.14 OAJ24429.1 - 0.77 9.0 4.4 1.4 8.2 4.4 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Seryl_tRNA_N PF02403.22 OAJ24429.1 - 2 8.7 9.5 4.4 7.6 9.5 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 OAJ24429.1 - 2.8 7.2 8.7 4.6 6.5 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 OAJ24429.1 - 3 7.1 12.8 4.8 6.5 12.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribosomal_L7Ae PF01248.26 OAJ24447.1 - 7.4e-22 76.9 0.1 1.8e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 OAJ24447.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 LicD PF04991.13 OAJ24447.1 - 0.23 11.6 5.3 0.3 11.2 5.3 1.2 1 0 0 1 1 1 0 LicD family CDC27 PF09507.10 OAJ24447.1 - 1.8 7.9 29.7 2.3 7.5 29.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4050 PF13259.6 OAJ24447.1 - 2 8.7 11.6 4 7.7 11.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) BAF1_ABF1 PF04684.13 OAJ24447.1 - 5.3 6.0 19.4 6.4 5.7 19.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.8 OAJ24447.1 - 8.5 5.4 9.2 2.2 7.4 6.3 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal rve PF00665.26 OAJ24448.1 - 2.1e-05 24.7 0.0 4.7e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MutS_V PF00488.21 OAJ24449.1 - 3.9e-65 219.4 0.8 7.7e-65 218.5 0.2 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 OAJ24449.1 - 2.9e-33 115.7 0.2 2.9e-33 115.7 0.2 2.2 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 OAJ24449.1 - 3.7e-22 78.7 2.9 6.5e-20 71.5 0.7 3.0 2 1 0 2 2 2 1 MutS domain I Acetyltransf_13 PF13880.6 OAJ24449.1 - 1e-13 51.1 0.0 2.3e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 OAJ24449.1 - 3.5e-13 49.1 2.3 7.5e-13 48.1 2.3 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO MutS_II PF05188.17 OAJ24449.1 - 6.5e-12 45.9 0.2 2.1e-11 44.3 0.2 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ24449.1 - 2e-06 28.0 0.5 1e-05 25.8 0.2 2.2 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 OAJ24449.1 - 0.039 13.7 1.9 0.12 12.1 0.2 2.7 3 0 0 3 3 3 0 AAA domain Fe-S_biosyn PF01521.20 OAJ24450.1 - 3.1e-15 56.3 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SUI1 PF01253.22 OAJ24470.1 - 2.2e-30 105.0 0.4 3.4e-30 104.4 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Importin_rep_3 PF18806.1 OAJ24472.1 - 0.085 12.9 0.2 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Importin 13 repeat I_LWEQ PF01608.17 OAJ24472.1 - 0.21 11.8 0.9 2.7 8.2 0.0 2.4 2 1 0 2 2 2 0 I/LWEQ domain EB PF01683.18 OAJ24474.1 - 0.018 15.3 2.3 0.018 15.3 2.3 3.8 3 2 0 3 3 3 0 EB module Dickkopf_N PF04706.12 OAJ24474.1 - 0.026 15.0 31.6 0.31 11.5 7.1 3.7 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF2721 PF11026.8 OAJ24475.1 - 0.016 15.1 0.3 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF5319 PF17252.2 OAJ24475.1 - 0.044 14.0 0.2 0.077 13.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5319) DUF2207 PF09972.9 OAJ24475.1 - 0.065 12.0 0.0 3.6 6.2 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) zf-rbx1 PF12678.7 OAJ24498.1 - 6.4e-13 48.8 2.8 1.1e-12 48.0 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ24498.1 - 5.5e-10 39.4 7.7 1.5e-09 38.0 7.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ24498.1 - 9.6e-07 28.6 2.5 1.9e-06 27.6 2.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 OAJ24498.1 - 1.2e-06 28.5 0.8 2.3e-06 27.6 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAJ24498.1 - 5.4e-06 26.3 3.1 9.6e-06 25.5 3.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ24498.1 - 1.1e-05 25.2 5.4 1.1e-05 25.2 5.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ24498.1 - 0.00014 21.7 2.9 0.00025 20.9 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ24498.1 - 0.00024 20.9 2.7 0.00043 20.1 2.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAJ24498.1 - 0.0014 18.5 7.1 0.01 15.7 7.3 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ24498.1 - 0.0014 18.2 2.3 0.0027 17.3 2.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 OAJ24498.1 - 0.0029 17.3 2.1 0.0029 17.3 2.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 OAJ24498.1 - 0.0078 16.3 3.0 0.013 15.6 2.2 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 OAJ24498.1 - 0.043 14.0 0.2 0.096 12.9 0.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 OAJ24498.1 - 0.49 10.8 3.9 0.84 10.0 3.9 1.3 1 0 0 1 1 1 0 RING-like domain Glycophorin_A PF01102.18 OAJ24499.1 - 0.0012 19.0 0.1 0.0012 19.0 0.1 1.9 2 0 0 2 2 2 1 Glycophorin A TMEM154 PF15102.6 OAJ24499.1 - 0.0053 16.7 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family MGC-24 PF05283.11 OAJ24499.1 - 0.0075 16.7 5.4 0.0075 16.7 5.4 2.3 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 OAJ24499.1 - 0.015 15.3 13.1 0.015 15.3 13.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Macoilin PF09726.9 OAJ24499.1 - 0.6 8.6 2.0 0.89 8.0 2.0 1.3 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 OAJ24500.1 - 3.2e-06 27.1 0.2 7.1e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF5305 PF17231.2 OAJ24500.1 - 0.019 14.4 0.4 0.028 13.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 OAJ24500.1 - 0.072 14.0 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Mucin PF01456.17 OAJ24500.1 - 0.2 11.6 24.6 0.018 15.0 18.3 2.2 3 0 0 3 3 3 0 Mucin-like glycoprotein MGC-24 PF05283.11 OAJ24500.1 - 0.52 10.8 11.0 0.17 12.3 5.4 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Dynamitin PF04912.14 OAJ24501.1 - 8e-39 134.1 0.0 9.9e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Dynamitin DUF2020 PF09449.10 OAJ24501.1 - 0.052 13.4 0.4 0.082 12.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Rnk_N PF14760.6 OAJ24501.1 - 0.093 13.2 3.0 0.18 12.3 0.2 2.7 2 0 0 2 2 2 0 Rnk N-terminus CAP_N PF01213.19 OAJ24502.1 - 1.8e-94 316.8 22.3 1.8e-94 316.8 22.3 4.0 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 OAJ24502.1 - 1.8e-53 180.4 3.7 2.3e-53 180.0 3.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 OAJ24502.1 - 0.0038 17.0 1.0 0.0067 16.1 1.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CCDC53 PF10152.9 OAJ24502.1 - 2.7 8.4 4.1 1.1 9.6 0.0 2.2 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Metal_resist PF13801.6 OAJ24502.1 - 9.1 6.5 13.5 14 5.9 3.4 2.9 3 0 0 3 3 3 0 Heavy-metal resistance NUDIX PF00293.28 OAJ24503.1 - 8.7e-20 71.1 0.2 6.5e-19 68.3 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 OAJ24503.1 - 0.057 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide hydrolase SnoaL_2 PF12680.7 OAJ24522.1 - 0.00049 20.7 0.3 0.014 16.0 0.0 2.8 2 1 1 3 3 3 1 SnoaL-like domain zf-C2H2 PF00096.26 OAJ24523.1 - 4.7e-06 26.8 2.8 0.035 14.6 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ24523.1 - 0.0012 19.5 1.7 1.9 9.6 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Mpp10 PF04006.12 OAJ24523.1 - 6.1 5.2 15.0 0.85 8.0 9.1 2.0 2 0 0 2 2 2 0 Mpp10 protein Sod_Fe_C PF02777.18 OAJ24548.1 - 2.9e-17 62.7 0.0 5e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ24548.1 - 0.04 14.4 0.0 0.065 13.7 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Hemerythrin PF01814.23 OAJ24549.1 - 2.8e-12 47.4 5.7 2.7e-10 41.0 3.3 2.0 1 1 0 2 2 2 2 Hemerythrin HHE cation binding domain BTB PF00651.31 OAJ24550.1 - 4.9e-07 29.9 0.0 9.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HbrB PF08539.11 OAJ24550.1 - 7.9 6.4 7.2 0.21 11.5 0.3 1.9 2 0 0 2 2 2 0 HbrB-like TMEM70 PF06979.12 OAJ24551.1 - 0.00046 20.6 0.1 0.00077 19.9 0.1 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex DUF1768 PF08719.11 OAJ24552.1 - 8.5e-25 87.9 0.0 1.2e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) F-box-like PF12937.7 OAJ24574.1 - 7.4e-05 22.6 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 OAJ24575.1 - 0.013 15.4 1.3 0.022 14.7 0.2 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 OAJ24575.1 - 0.24 11.3 1.5 0.54 10.2 0.3 2.2 2 0 0 2 2 2 0 F-box domain RRF PF01765.19 OAJ24576.1 - 0.0097 15.9 0.2 0.013 15.5 0.2 1.3 1 1 0 1 1 1 1 Ribosome recycling factor Calc_CGRP_IAPP PF00214.19 OAJ24576.1 - 0.043 14.2 0.9 0.049 14.0 0.9 1.3 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family CpXC PF14353.6 OAJ24576.1 - 0.085 12.9 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 CpXC protein DUF1192 PF06698.11 OAJ24576.1 - 9.6 6.3 10.9 0.22 11.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TPR_10 PF13374.6 OAJ24577.1 - 0.011 15.6 0.7 0.12 12.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ24577.1 - 0.022 15.0 1.5 0.13 12.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ24577.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 PI3K_1B_p101 PF10486.9 OAJ24577.1 - 0.15 9.8 3.0 0.22 9.3 3.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Uds1 PF15456.6 OAJ24577.1 - 0.21 11.8 2.7 0.75 10.0 2.7 1.9 1 0 0 1 1 1 0 Up-regulated During Septation Rrp44_CSD1 PF17216.3 OAJ24577.1 - 1.6 8.4 6.1 2.4 7.9 4.8 1.8 2 0 0 2 2 2 0 Rrp44-like cold shock domain DUF515 PF04415.12 OAJ24577.1 - 4.8 5.5 8.3 7.5 4.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-CCHC PF00098.23 OAJ24601.1 - 0.044 13.9 1.3 0.11 12.6 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle TAF4 PF05236.14 OAJ24601.1 - 0.085 12.6 1.6 0.2 11.4 1.6 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family IATP PF04568.12 OAJ24601.1 - 4.9 7.6 7.8 10 6.6 6.8 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF3446 PF11928.8 OAJ24602.1 - 0.017 15.4 1.4 0.017 15.4 1.4 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Croc_4 PF17691.1 OAJ24602.1 - 0.72 9.9 5.2 0.12 12.4 0.6 1.9 2 0 0 2 2 2 0 Contingent replication of cDNA 4 HAD_2 PF13419.6 OAJ24603.1 - 1.7e-12 47.8 0.0 3.8e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ24603.1 - 3.2e-08 34.1 0.0 1.4e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ24603.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ24603.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase TRAUB PF08164.12 OAJ24604.1 - 2.4e-23 82.4 0.0 1.8e-22 79.7 0.0 2.5 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 OAJ24604.1 - 7.1e-09 36.5 4.2 7.1e-09 36.5 4.2 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor Pkinase PF00069.25 OAJ24605.1 - 3e-71 239.9 0.0 3.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ24605.1 - 1.9e-34 119.1 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ24605.1 - 0.025 13.9 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 OAJ24605.1 - 0.03 13.3 0.0 0.33 9.8 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain DUF3811 PF11656.8 OAJ24626.1 - 0.017 15.5 0.9 0.023 15.1 0.9 1.2 1 0 0 1 1 1 0 YjbD family (DUF3811) OrfB_Zn_ribbon PF07282.11 OAJ24648.1 - 0.00013 21.8 0.8 0.098 12.6 0.1 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DUF3932 PF13068.6 OAJ24648.1 - 0.023 15.0 0.2 0.059 13.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Curto_V3 PF07436.11 OAJ24648.1 - 0.24 11.8 1.9 9.6 6.7 0.2 2.6 1 1 1 2 2 2 0 Curtovirus V3 protein TFIIA PF03153.13 OAJ24650.1 - 0.0019 18.3 7.2 0.0019 18.3 7.2 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 OAJ24650.1 - 0.029 12.5 15.5 0.054 11.6 15.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 OAJ24650.1 - 0.29 11.0 3.8 0.72 9.7 2.9 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain CAF1A PF12253.8 OAJ24650.1 - 4.1 7.6 15.1 13 6.0 15.1 1.9 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Cwf_Cwc_15 PF04889.12 OAJ24650.1 - 6.9 6.3 17.7 23 4.6 17.7 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dimer_Tnp_hAT PF05699.14 OAJ24651.1 - 1.2e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Alpha-amylase PF00128.24 OAJ24677.1 - 2.2e-98 329.9 0.0 3.1e-98 329.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 OAJ24677.1 - 0.0036 16.4 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF2838 PF10998.8 OAJ24678.1 - 7.6e-41 138.8 9.0 7.6e-41 138.8 9.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF454 PF04304.13 OAJ24678.1 - 0.032 14.2 3.1 0.85 9.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF454) Cellulase PF00150.18 OAJ24679.1 - 2.9e-09 36.8 9.7 3.4e-09 36.6 8.9 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DPBB_1 PF03330.18 OAJ24705.1 - 5.9e-07 29.7 0.1 1e-06 28.9 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Abhydrolase_3 PF07859.13 OAJ24706.1 - 3.5e-39 134.8 0.0 3.3e-31 108.8 0.0 2.8 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ24706.1 - 9.9e-11 41.1 0.0 3.2e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 OAJ24706.1 - 0.0045 15.9 0.1 0.14 11.0 0.0 3.0 4 0 0 4 4 4 1 Carboxylesterase family Peptidase_S9 PF00326.21 OAJ24706.1 - 0.15 11.5 0.0 0.37 10.2 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family CFEM PF05730.11 OAJ24724.1 - 6.9e-08 32.5 9.9 1.1e-07 31.9 9.9 1.2 1 0 0 1 1 1 1 CFEM domain PglL_A PF15864.5 OAJ24724.1 - 0.019 14.7 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein glycosylation ligase TIL PF01826.17 OAJ24724.1 - 1.6 9.1 7.8 2.6 8.3 7.8 1.3 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain CFEM PF05730.11 OAJ24725.1 - 0.0033 17.5 10.3 0.02 15.0 4.0 2.3 2 0 0 2 2 2 2 CFEM domain CFEM PF05730.11 OAJ24726.1 - 8.4e-07 29.0 12.1 1.7e-06 28.0 12.1 1.6 1 1 0 1 1 1 1 CFEM domain Toxin_3 PF00537.18 OAJ24726.1 - 0.073 13.3 6.6 0.16 12.2 6.6 1.5 1 0 0 1 1 1 0 Scorpion toxin-like domain WD40 PF00400.32 OAJ24727.1 - 5.4e-09 36.5 13.9 0.01 16.7 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ24727.1 - 0.0016 18.7 0.0 1.2 9.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_D PF01813.17 OAJ24728.1 - 1.2e-72 243.9 2.4 1.8e-72 243.3 2.4 1.3 1 0 0 1 1 1 1 ATP synthase subunit D XRN_M PF17846.1 OAJ24728.1 - 0.59 9.0 2.5 0.92 8.4 2.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain NOA36 PF06524.12 OAJ24728.1 - 0.72 9.1 6.9 1.2 8.3 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 OAJ24728.1 - 3.3 7.6 14.5 4.7 7.1 14.5 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.6 OAJ24728.1 - 9.8 6.1 11.3 2.1 8.2 8.1 1.5 2 0 0 2 2 2 0 Spore coat protein CotO RRM_1 PF00076.22 OAJ24729.1 - 2.3e-12 46.5 0.0 3.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ24729.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif YqeY PF09424.10 OAJ24730.1 - 7.5e-24 84.4 1.0 9.5e-24 84.1 1.0 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF2880 PF11082.8 OAJ24730.1 - 0.01 16.1 0.9 0.03 14.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) DUF3365 PF11845.8 OAJ24730.1 - 0.019 15.3 0.1 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) PAP_assoc PF03828.19 OAJ24754.1 - 4.7e-14 52.3 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ24754.1 - 6.7e-10 39.1 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_C93 PF06035.11 OAJ24754.1 - 0.12 12.1 0.4 8.6 6.1 0.0 2.6 3 0 0 3 3 3 0 Bacterial transglutaminase-like cysteine proteinase BTLCP SPT6_acidic PF14632.6 OAJ24754.1 - 6.2 7.5 13.1 0.8 10.3 1.2 3.5 2 1 1 3 3 3 0 Acidic N-terminal SPT6 DEAD PF00270.29 OAJ24755.1 - 1.4e-19 70.5 0.0 2.1e-16 60.2 0.0 3.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ24755.1 - 0.0002 21.6 1.7 0.0051 17.1 1.7 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ24755.1 - 0.00056 20.0 0.0 0.0018 18.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BORG_CEP PF14957.6 OAJ24755.1 - 0.67 11.1 7.7 1.1 10.4 3.5 2.6 2 0 0 2 2 2 0 Cdc42 effector DEAD PF00270.29 OAJ24756.1 - 5.2e-50 169.6 0.0 2.9e-49 167.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ24756.1 - 5.2e-27 94.4 0.0 3.9e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ24756.1 - 0.0031 17.5 0.0 0.0087 16.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YqgF PF14639.6 OAJ24756.1 - 0.29 10.9 3.0 8.6 6.1 0.3 3.0 2 1 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 MIF4G PF02854.19 OAJ24777.1 - 1.1e-54 185.3 1.1 2e-54 184.4 1.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 OAJ24777.1 - 3.8e-13 49.4 0.0 1.2e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 FANCI_S2 PF14676.6 OAJ24777.1 - 0.14 12.5 0.2 49 4.2 0.0 3.6 3 0 0 3 3 3 0 FANCI solenoid 2 Y_phosphatase2 PF03162.13 OAJ24778.1 - 3.2e-50 169.9 0.0 3.6e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ24778.1 - 0.00055 20.0 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ24778.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HTH_CodY PF08222.11 OAJ24778.1 - 0.16 11.6 0.0 0.66 9.6 0.0 2.0 2 1 0 2 2 2 0 CodY helix-turn-helix domain PseudoU_synth_2 PF00849.22 OAJ24779.1 - 1.9e-26 93.1 0.1 2.9e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_L22 PF00237.19 OAJ24801.1 - 5.8e-25 87.5 0.5 5.8e-25 87.5 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e KAR9 PF08580.10 OAJ24801.1 - 0.041 12.4 0.4 0.045 12.3 0.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SIR2 PF02146.17 OAJ24802.1 - 5.8e-30 104.5 0.0 2.5e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Sir2 family ADH_zinc_N PF00107.26 OAJ24803.1 - 6.8e-27 94.0 0.2 1e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ24803.1 - 4.3e-13 50.5 0.0 7.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ24803.1 - 3.3e-08 33.4 0.0 7.5e-07 29.0 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain HupF_HypC PF01455.18 OAJ24803.1 - 0.17 12.1 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family SPT_ssu-like PF11779.8 OAJ24804.1 - 1.5e-06 27.8 0.4 2.1e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Jiraiya PF15038.6 OAJ24804.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 Jiraiya Epiglycanin_C PF14654.6 OAJ24804.1 - 0.034 14.2 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Smim3 PF17307.2 OAJ24804.1 - 0.035 13.6 2.0 0.064 12.8 2.0 1.4 1 0 0 1 1 1 0 Small integral membrane protein 3 PMP1_2 PF08114.11 OAJ24804.1 - 8.5 6.2 7.1 0.29 10.9 0.6 1.8 2 0 0 2 2 2 0 ATPase proteolipid family Hva1_TUDOR PF11160.8 OAJ24805.1 - 3.7e-18 65.4 1.3 4.4e-18 65.2 1.3 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain 2OG-FeII_Oxy_3 PF13640.6 OAJ24851.1 - 7.1e-05 23.6 0.0 0.00018 22.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Phage_integrase PF00589.22 OAJ24852.1 - 0.0061 16.4 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Peroxin-3 PF04882.12 OAJ24853.1 - 2.8e-13 49.7 0.0 5.1e-11 42.2 0.0 2.2 1 1 1 2 2 2 2 Peroxin-3 DUF676 PF05057.14 OAJ24880.1 - 2.7e-29 102.3 0.0 4.9e-24 85.1 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) GREB1 PF15782.5 OAJ24880.1 - 0.013 12.7 1.8 0.017 12.3 1.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF676 PF05057.14 OAJ24881.1 - 9.9e-27 93.9 0.0 1.9e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAJ24881.1 - 0.0081 16.8 1.1 0.0081 16.8 1.1 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ24881.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein SNF2_N PF00176.23 OAJ24882.1 - 3.7e-61 206.8 0.0 1.5e-59 201.5 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ24882.1 - 8.8e-22 77.6 0.2 5.8e-20 71.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ24882.1 - 7.7e-09 35.8 0.0 3.3e-08 33.7 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ24882.1 - 3.5e-08 33.0 0.4 1.3e-06 27.8 0.0 2.8 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 E1_dh PF00676.20 OAJ24882.1 - 0.031 13.2 1.2 0.053 12.5 1.2 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component EXOSC1 PF10447.9 OAJ24899.1 - 1.7e-25 89.7 0.1 3.9e-25 88.6 0.1 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 TFIIS_M PF07500.14 OAJ24900.1 - 9.3e-22 77.6 0.1 1.5e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 OAJ24900.1 - 3e-10 39.8 7.0 4.6e-10 39.2 7.0 1.3 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 OAJ24900.1 - 1.4e-06 28.3 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_4 PF16866.5 OAJ24900.1 - 0.089 12.9 2.4 0.18 11.9 2.4 1.4 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 OAJ24900.1 - 0.47 10.1 1.6 0.77 9.4 1.6 1.4 1 0 0 1 1 1 0 PHD-finger Hid1 PF12722.7 OAJ24900.1 - 4.2 5.4 4.8 6.6 4.7 4.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_2 PF13639.6 OAJ24900.1 - 6.4 7.2 5.9 12 6.3 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain CENP-H PF05837.12 OAJ24901.1 - 0.0039 17.6 14.8 0.01 16.2 9.7 2.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) HAP1_N PF04849.13 OAJ24901.1 - 0.027 13.7 24.9 0.077 12.2 23.9 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region GAS PF13851.6 OAJ24901.1 - 0.14 11.5 13.4 2.2 7.6 7.4 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 OAJ24901.1 - 0.23 11.3 16.8 0.52 10.1 8.7 3.0 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 OAJ24901.1 - 0.28 11.2 15.9 0.24 11.4 3.4 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phlebovirus_NSM PF07246.11 OAJ24901.1 - 0.58 9.5 6.9 1.5 8.1 4.1 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF948 PF06103.11 OAJ24901.1 - 0.79 10.0 2.5 6.7 7.0 0.1 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) JIP_LZII PF16471.5 OAJ24901.1 - 2.1 8.6 13.0 0.24 11.6 0.6 3.8 3 1 2 5 5 5 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 OAJ24901.1 - 3.4 7.9 16.6 2.1 8.6 0.2 3.5 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 OAJ24901.1 - 3.9 7.8 10.8 4.5 7.6 0.2 4.8 6 0 0 6 6 5 0 Homeobox associated leucine zipper DivIVA PF05103.13 OAJ24901.1 - 5.1 7.2 13.5 6.9 6.8 0.0 3.6 2 1 1 3 3 3 0 DivIVA protein Fungal_TACC PF12709.7 OAJ24901.1 - 7.2 7.1 5.9 14 6.2 0.2 3.6 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 OAJ24901.1 - 8 5.2 19.5 23 3.7 4.9 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Peptidase_C97 PF05903.14 OAJ24902.1 - 5.7e-17 61.9 0.0 2.5e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 PPPDE putative peptidase domain DUF4796 PF16044.5 OAJ24902.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Diphthami_syn_2 PF01902.17 OAJ24926.1 - 1.5e-38 132.5 0.0 4.9e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 OAJ24926.1 - 1.1e-21 77.1 0.1 9.7e-15 54.6 0.1 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.16 OAJ24926.1 - 0.0055 15.5 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase VEFS-Box PF09733.9 OAJ24926.1 - 0.2 11.5 0.1 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 VEFS-Box of polycomb protein MRI PF15325.6 OAJ24926.1 - 3.4 8.8 6.6 28 5.9 0.1 3.3 3 0 0 3 3 3 0 Modulator of retrovirus infection NMD3 PF04981.13 OAJ24927.1 - 2.9e-80 269.3 0.5 3.7e-80 268.9 0.5 1.1 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 OAJ24927.1 - 0.033 14.2 8.4 0.33 11.0 5.3 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-NADH-PPase PF09297.11 OAJ24927.1 - 6.7 6.5 5.4 0.61 9.8 0.2 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Complex1_LYR_2 PF13233.6 OAJ24946.1 - 2.3e-18 66.7 0.1 3.5e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 OAJ24946.1 - 8.2e-10 38.6 0.1 1.5e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) A_deamin PF02137.18 OAJ24947.1 - 3.7e-40 138.4 0.0 5.7e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Asp PF00026.23 OAJ24948.1 - 8.5e-30 104.2 1.2 1.4e-09 37.8 0.0 3.6 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ24948.1 - 1.2e-09 38.7 3.9 6.9e-06 26.4 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Ribosomal_L36e PF01158.18 OAJ24949.1 - 1.9e-38 130.6 6.0 2.3e-38 130.3 6.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e CTP_transf_1 PF01148.20 OAJ24950.1 - 8.9e-68 228.9 16.7 1e-63 215.6 11.2 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family TMCO5 PF14992.6 OAJ24950.1 - 0.12 12.0 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 TMCO5 family ATP-synt_B PF00430.18 OAJ24950.1 - 3.2 7.8 7.0 7.2 6.7 7.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4231 PF14015.6 OAJ24978.1 - 1.6 9.2 15.0 4.3 7.9 5.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Acyl_transf_1 PF00698.21 OAJ24979.1 - 2e-10 40.7 0.0 1.1e-05 25.1 0.0 2.9 1 1 1 2 2 2 2 Acyl transferase domain Hexapep PF00132.24 OAJ24980.1 - 1.2e-12 47.0 5.7 2.4e-10 39.7 3.2 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ24980.1 - 1.7e-12 46.8 7.0 1.7e-10 40.4 3.3 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 OAJ24980.1 - 6.3e-07 29.5 0.0 2.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 OAJ24981.1 - 1.9e-11 43.5 2.8 5.9e-09 35.5 1.4 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 OAJ24981.1 - 2.2e-11 43.0 1.7 4.2e-08 32.6 0.9 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 OAJ24981.1 - 9.3e-10 38.6 0.3 3.4e-09 36.8 0.0 2.0 2 1 0 2 2 2 1 Maltose acetyltransferase WW PF00397.26 OAJ25009.1 - 2.2e-08 34.1 0.6 3e-08 33.6 0.6 1.2 1 0 0 1 1 1 1 WW domain ATG11 PF10377.9 OAJ25010.1 - 5.4e-27 94.4 0.0 1.7e-26 92.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 11 GIT_CC PF16559.5 OAJ25010.1 - 0.16 11.8 0.3 13 5.8 0.1 3.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Baculo_PEP_C PF04513.12 OAJ25010.1 - 7.7 6.6 18.6 1.2 9.2 0.3 4.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 OAJ25010.1 - 10 6.3 21.8 0.072 13.3 1.1 4.7 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family ABC2_membrane PF01061.24 OAJ25030.1 - 2.6e-33 115.2 17.5 2.6e-33 115.2 17.5 1.8 3 0 0 3 3 1 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ25030.1 - 4.8e-26 91.9 0.0 7.5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ25030.1 - 3.9e-06 26.9 0.6 0.032 14.1 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ25030.1 - 3.5e-05 24.3 0.2 8.4e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAJ25030.1 - 0.00021 20.9 0.1 0.00043 19.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ25030.1 - 0.001 19.3 0.0 0.0037 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 OAJ25030.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 OAJ25030.1 - 0.0035 17.0 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ25030.1 - 0.0046 17.5 0.0 0.0088 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ25030.1 - 0.0087 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 OAJ25030.1 - 0.012 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAJ25030.1 - 0.018 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ25030.1 - 0.021 15.3 0.1 0.035 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ25030.1 - 0.024 14.4 0.2 0.046 13.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 OAJ25030.1 - 0.065 13.5 0.1 0.57 10.5 0.1 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OAJ25030.1 - 0.07 13.6 0.0 1.1 9.7 0.0 2.5 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAJ25030.1 - 0.08 13.0 0.1 0.18 11.9 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 OAJ25030.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ25030.1 - 0.14 11.9 0.2 2.1 8.0 0.2 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 OAJ25030.1 - 0.24 11.3 0.0 4 7.3 0.1 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 OAJ25030.1 - 0.25 11.4 0.0 0.46 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L19 PF01245.20 OAJ25031.1 - 2.3e-15 56.5 0.1 4.2e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Not3 PF04065.15 OAJ25032.1 - 4.4e-91 304.4 17.4 4.4e-91 304.4 17.4 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 OAJ25032.1 - 5.9e-46 155.8 11.4 5.9e-46 155.8 11.4 2.8 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 OAJ25032.1 - 0.0027 17.5 3.0 0.008 16.0 3.0 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) XRN_N PF03159.18 OAJ25032.1 - 8.9 5.7 11.7 28 4.0 11.7 1.8 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus KDZ PF18758.1 OAJ25055.1 - 9e-05 22.2 0.5 0.00014 21.6 0.4 1.3 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RVT_1 PF00078.27 OAJ25056.1 - 6.4e-27 94.5 0.0 1.1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spt20 PF12090.8 OAJ25056.1 - 0.22 11.1 6.0 0.37 10.3 6.0 1.4 1 0 0 1 1 1 0 Spt20 family RTC_insert PF05189.13 OAJ25058.1 - 0.0037 17.8 0.1 0.011 16.3 0.1 1.8 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Astro_capsid_p PF12226.8 OAJ25058.1 - 0.013 14.6 0.3 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Na_trans_assoc PF06512.13 OAJ25058.1 - 0.024 14.9 2.1 0.044 14.1 2.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated BUD22 PF09073.10 OAJ25058.1 - 0.038 13.4 9.3 0.054 12.8 9.3 1.1 1 0 0 1 1 1 0 BUD22 DBD_Tnp_Hermes PF10683.9 OAJ25058.1 - 0.16 11.7 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain Transposase_21 PF02992.14 OAJ25083.1 - 3.7e-10 39.4 0.3 1.2e-09 37.8 0.0 1.9 3 0 0 3 3 3 1 Transposase family tnp2 GEMIN8 PF15348.6 OAJ25084.1 - 0.54 10.5 8.3 4.6 7.5 5.8 2.3 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Folliculin PF11704.8 OAJ25084.1 - 1.2 9.0 5.4 16 5.3 0.1 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Retrotrans_gag PF03732.17 OAJ25104.1 - 0.032 14.5 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein Pkinase PF00069.25 OAJ25105.1 - 1.1e-38 133.1 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25105.1 - 1.1e-20 74.1 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RTC4 PF14474.6 OAJ25105.1 - 8.6e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 RTC4-like domain APH PF01636.23 OAJ25105.1 - 0.0015 18.5 0.1 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ25105.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAJ25105.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dimer_Tnp_hAT PF05699.14 OAJ25106.1 - 3e-15 55.8 0.0 6.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nop14 PF04147.12 OAJ25106.1 - 0.049 11.8 21.5 0.097 10.9 21.5 1.4 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 OAJ25106.1 - 0.89 9.2 15.6 1.9 8.1 15.6 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) YL1 PF05764.13 OAJ25106.1 - 0.91 9.6 31.0 0.061 13.4 24.8 2.2 1 1 1 2 2 2 0 YL1 nuclear protein Myc_N PF01056.18 OAJ25106.1 - 1.5 8.7 8.1 3.9 7.3 8.1 1.7 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 OAJ25106.1 - 2.5 6.3 16.1 4.4 5.5 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Prothymosin PF03247.14 OAJ25106.1 - 5.6 7.5 36.0 7.9 7.0 26.5 2.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family LRR_4 PF12799.7 OAJ25134.1 - 7.9e-27 92.9 25.3 4e-05 23.9 0.3 8.2 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ25134.1 - 1.1e-22 79.5 26.6 3.2e-10 39.6 3.3 5.5 5 0 0 5 5 5 3 Leucine rich repeat LRR_9 PF14580.6 OAJ25134.1 - 1.7e-09 37.4 14.6 5.5e-05 22.7 0.2 4.5 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 OAJ25134.1 - 2.4e-05 24.3 25.4 4.3 8.3 0.0 9.5 10 0 0 10 10 10 3 Leucine Rich Repeat BSP_II PF05432.11 OAJ25134.1 - 0.0031 17.3 1.8 0.0031 17.3 1.8 4.3 5 1 0 5 5 5 1 Bone sialoprotein II (BSP-II) LRR_6 PF13516.6 OAJ25134.1 - 0.011 15.7 28.9 0.69 10.1 0.3 8.9 8 1 1 9 9 9 0 Leucine Rich repeat JAB PF01398.21 OAJ25135.1 - 1.8e-13 50.5 0.0 3.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 OAJ25135.1 - 1.5e-05 24.8 0.4 3.4e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UIM PF02809.20 OAJ25135.1 - 0.66 10.0 4.7 1.5 8.9 4.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Hid1 PF12722.7 OAJ25135.1 - 1.6 6.8 6.8 2.3 6.2 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DnaJ PF00226.31 OAJ25136.1 - 5e-12 45.8 0.0 4.6e-08 33.1 0.0 2.8 3 0 0 3 3 3 2 DnaJ domain zf-CSL PF05207.13 OAJ25136.1 - 8.4e-09 35.0 4.6 2e-08 33.8 1.7 2.8 2 1 0 2 2 2 1 CSL zinc finger E7 PF00527.18 OAJ25136.1 - 0.14 12.4 1.6 0.31 11.2 0.2 2.2 2 1 0 2 2 2 0 E7 protein, Early protein APH PF01636.23 OAJ25137.1 - 1e-10 42.0 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ25137.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 OAJ25137.1 - 0.068 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DNA_pol_viral_C PF00336.18 OAJ25188.1 - 0.064 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain zf-CCHC PF00098.23 OAJ25188.1 - 0.097 12.8 1.3 0.23 11.6 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Glyco_transf_24 PF18404.1 OAJ25189.1 - 1.2e-142 474.1 1.9 1.8e-142 473.5 1.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 OAJ25189.1 - 4.8e-48 164.3 0.1 2.5e-46 158.7 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 OAJ25189.1 - 2.4e-35 120.9 0.0 4.4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 OAJ25189.1 - 2.4e-34 118.9 0.0 1.3e-33 116.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 OAJ25189.1 - 4e-33 115.2 0.0 9.4e-29 100.9 0.0 3.7 4 1 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 OAJ25189.1 - 8.3e-28 97.0 0.0 2.5e-27 95.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 OAJ25189.1 - 1.6e-05 24.6 0.1 3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 PspA_IM30 PF04012.12 OAJ25189.1 - 0.18 11.4 2.4 0.41 10.2 0.4 2.2 2 0 0 2 2 2 0 PspA/IM30 family Mit_ribos_Mrp51 PF11709.8 OAJ25242.1 - 0.0031 17.2 3.1 1.3 8.6 0.2 3.1 2 1 1 3 3 3 2 Mitochondrial ribosomal protein subunit zf-Mss51 PF13824.6 OAJ25243.1 - 5.7e-22 77.6 2.2 1.3e-21 76.4 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Calreticulin PF00262.18 OAJ25245.1 - 1.1e-160 534.5 11.6 1.4e-160 534.2 11.6 1.1 1 0 0 1 1 1 1 Calreticulin family DUF883 PF05957.13 OAJ25245.1 - 0.0031 18.1 2.7 0.0031 18.1 2.7 1.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) MtrD PF04207.12 OAJ25245.1 - 0.0036 17.0 0.7 0.0055 16.4 0.7 1.2 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D Rad52_Rad22 PF04098.15 OAJ25245.1 - 0.34 10.8 5.1 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein 2_5_RNA_ligase2 PF13563.6 OAJ25271.1 - 1.3e-17 64.1 2.0 5.7e-10 39.3 0.2 2.2 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 OAJ25271.1 - 7.8e-05 22.8 0.1 0.25 11.5 0.0 3.2 3 0 0 3 3 3 2 LigT like Phosphoesterase CPDase PF07823.11 OAJ25271.1 - 0.17 11.6 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein HU-CCDC81_bac_2 PF18175.1 OAJ25271.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 TpcC PF12642.7 OAJ25272.1 - 0.17 11.7 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 Conjugative transposon protein TcpC DIM PF08194.12 OAJ25273.1 - 0.34 11.2 1.8 0.54 10.5 1.8 1.3 1 0 0 1 1 1 0 DIM protein TruB_N PF01509.18 OAJ25274.1 - 8.4e-37 126.8 0.0 9.6e-36 123.4 0.0 2.2 1 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ25274.1 - 1e-06 28.8 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF4637 PF15470.6 OAJ25274.1 - 3.7 7.3 8.2 0.21 11.3 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) CENP-B_dimeris PF09026.10 OAJ25275.1 - 2 8.9 7.0 0.17 12.3 1.9 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 OAJ25275.1 - 2.3 6.3 10.6 3.2 5.9 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family MOR2-PAG1_N PF14222.6 OAJ25297.1 - 7.8e-111 371.7 0.0 1.6e-110 370.7 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 OAJ25297.1 - 7.2e-74 248.8 8.3 7.4e-74 248.8 3.4 3.1 3 1 1 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 OAJ25297.1 - 1.6e-19 69.2 1.1 1.5e-07 29.5 0.0 4.6 5 0 0 5 5 5 4 Cell morphogenesis central region Fungal_trans PF04082.18 OAJ25298.1 - 1.1e-27 96.8 0.0 3.3e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ25298.1 - 3e-08 33.7 6.1 5.5e-08 32.8 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_23 PF17931.1 OAJ25298.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DDE_1 PF03184.19 OAJ25322.1 - 1.9e-17 63.4 0.0 4.7e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ25322.1 - 1.2e-08 34.9 0.0 4.3e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ25322.1 - 0.0051 16.6 0.4 0.069 12.9 0.0 2.8 4 0 0 4 4 4 1 DDE superfamily endonuclease Mg_trans_NIPA PF05653.14 OAJ25323.1 - 3.8e-61 206.8 0.2 1.5e-56 191.7 0.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 OAJ25323.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 3.0 3 1 0 3 3 3 1 EamA-like transporter family 7TMR-DISM_7TM PF07695.11 OAJ25323.1 - 0.025 14.5 4.3 0.063 13.2 4.3 1.7 1 0 0 1 1 1 0 7TM diverse intracellular signalling Pkinase PF00069.25 OAJ25324.1 - 1.1e-65 221.6 0.0 2.2e-65 220.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ25324.1 - 5.2e-35 121.0 0.0 2.6e-34 118.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 OAJ25324.1 - 3.8e-10 39.4 0.1 6.8e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 OAJ25324.1 - 7.4e-08 32.0 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ25324.1 - 0.0059 15.6 0.3 0.01 14.8 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ25324.1 - 0.027 14.4 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ25324.1 - 0.044 12.6 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 OAJ25324.1 - 0.096 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Herpes_UL73 PF03554.13 OAJ25348.1 - 0.2 11.7 0.9 0.45 10.6 0.9 1.5 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein AMP-binding_C PF13193.6 OAJ25348.1 - 0.23 12.4 0.0 0.43 11.6 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pyrid_oxidase_2 PF13883.6 OAJ25349.1 - 2.8e-25 89.2 0.0 3.9e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Kelch_2 PF07646.15 OAJ25349.1 - 0.045 13.7 0.8 1.8 8.7 0.4 2.9 2 1 0 2 2 2 0 Kelch motif GDI PF00996.18 OAJ25350.1 - 1.7e-205 682.6 0.0 2.2e-205 682.2 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 OAJ25350.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.21 OAJ25351.1 - 2.7e-95 320.0 0.0 6e-95 318.8 0.0 1.5 1 1 0 1 1 1 1 Amidase ECH_1 PF00378.20 OAJ25352.1 - 8.6e-48 162.8 0.0 2.3e-41 141.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ25352.1 - 2e-25 90.0 0.1 1.8e-16 60.6 0.0 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase DUF755 PF05501.11 OAJ25352.1 - 2.2 8.6 7.9 3.8 7.8 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4407 PF14362.6 OAJ25381.1 - 0.0032 16.9 16.7 0.049 13.0 5.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) BIRC6 PF12356.8 OAJ25381.1 - 3.5 7.0 7.6 0.26 10.7 1.1 2.4 2 0 0 2 2 2 0 Baculoviral IAP repeat-containing protein 6 Cupin_1 PF00190.22 OAJ25382.1 - 7.5e-40 136.0 0.0 6.1e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 OAJ25382.1 - 3.8e-26 90.6 0.5 9.2e-14 50.9 0.1 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 OAJ25382.1 - 4.5e-10 39.6 0.4 3e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 OAJ25382.1 - 5.7e-07 29.1 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_7 PF12973.7 OAJ25382.1 - 0.00066 19.6 0.2 0.19 11.7 0.0 2.7 2 1 0 2 2 2 1 ChrR Cupin-like domain MannoseP_isomer PF01050.18 OAJ25382.1 - 0.001 19.0 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase 3-HAO PF06052.12 OAJ25382.1 - 0.014 15.0 0.0 5.8 6.5 0.0 2.5 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_6 PF12852.7 OAJ25382.1 - 0.04 13.6 0.1 0.25 11.1 0.1 2.3 1 1 1 2 2 2 0 Cupin ARD PF03079.14 OAJ25382.1 - 0.052 13.7 0.0 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 ARD/ARD' family GPI PF06560.11 OAJ25382.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) PemK_toxin PF02452.17 OAJ25382.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system Sugar_tr PF00083.24 OAJ25383.1 - 1.7e-119 399.7 18.5 1.8e-118 396.3 18.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ25383.1 - 1.3e-20 73.6 61.7 6.2e-19 68.1 35.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TrkA_TMD PF18613.1 OAJ25383.1 - 0.27 10.7 4.0 9.2 5.8 0.2 2.8 2 0 0 2 2 2 0 Tyrosine kinase receptor A trans-membrane domain DUF441 PF04284.13 OAJ25383.1 - 0.45 10.5 9.3 0.78 9.7 7.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF441) 4HBT_3 PF13622.6 OAJ25384.1 - 4.9e-32 112.1 0.2 7.6e-32 111.5 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ25384.1 - 5.8e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA thioesterase M64_N PF16217.5 OAJ25384.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase M64 N-terminus Alk_phosphatase PF00245.20 OAJ25418.1 - 1e-05 24.7 0.0 1.9e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Peptidase_M20 PF01546.28 OAJ25419.1 - 1.4e-31 109.8 0.0 1.8e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ25419.1 - 2.4e-13 49.9 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Coatomer_WDAD PF04053.14 OAJ25420.1 - 7.6e-138 460.3 0.0 1.2e-137 459.7 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 OAJ25420.1 - 4.5e-96 322.1 0.0 5.6e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 OAJ25420.1 - 2.1e-42 142.2 11.8 1.1e-08 35.5 0.3 8.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ25420.1 - 8.4e-13 48.4 0.2 0.0011 19.3 0.0 6.5 4 1 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 OAJ25420.1 - 0.0099 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS TPR_2 PF07719.17 OAJ25420.1 - 0.1 12.8 0.1 13 6.2 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Nup160 PF11715.8 OAJ25420.1 - 0.18 10.4 5.1 1.5 7.4 0.0 3.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 TPR_14 PF13428.6 OAJ25420.1 - 2.3 9.3 8.4 1.9e+02 3.3 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PGA2 PF07543.12 OAJ25421.1 - 0.02 14.9 2.4 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 SOG2 PF10428.9 OAJ25421.1 - 0.04 13.1 11.0 0.063 12.5 11.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein SLC12 PF03522.15 OAJ25421.1 - 0.75 8.8 7.6 1.1 8.2 7.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 TFIIA PF03153.13 OAJ25421.1 - 1 9.3 16.3 0.11 12.5 11.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 OAJ25421.1 - 4.3 5.8 14.0 0.86 8.1 10.6 1.4 2 0 0 2 2 2 0 Macoilin family Hid1 PF12722.7 OAJ25421.1 - 7.1 4.6 10.7 9.1 4.3 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 OAJ25421.1 - 9.2 5.4 7.9 15 4.6 7.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M24 PF00557.24 OAJ25422.1 - 1.1e-47 162.4 0.0 1.4e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Med26 PF08711.11 OAJ25423.1 - 7.8e-07 29.0 0.1 7.8e-07 29.0 0.1 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Cytochrom_C_2 PF01322.20 OAJ25423.1 - 0.033 15.1 1.2 0.057 14.3 1.1 1.4 1 1 0 1 1 1 0 Cytochrome C' KDZ PF18758.1 OAJ25424.1 - 1.1e-47 162.5 0.0 2.2e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 OAJ25424.1 - 9.9e-06 25.7 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 OAJ25424.1 - 5e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CAF1 PF04857.20 OAJ25425.1 - 9.6e-22 77.5 0.0 5.9e-11 42.1 0.0 2.4 2 1 0 2 2 2 2 CAF1 family ribonuclease VWA_2 PF13519.6 OAJ25427.1 - 3.8e-23 82.2 0.1 9.1e-23 81.0 0.1 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 OAJ25427.1 - 0.00013 21.7 2.7 0.015 15.2 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Ssl1 PF04056.14 OAJ25427.1 - 0.00054 19.8 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like DNA_pol_phi PF04931.13 OAJ25427.1 - 4.2 5.4 5.0 5.6 4.9 5.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFA2_Winged_2 PF18121.1 OAJ25454.1 - 5.3e-11 42.1 0.1 1.4e-10 40.7 0.1 1.7 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 OAJ25454.1 - 7.3e-11 42.2 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE beta subunit core domain SH3_1 PF00018.28 OAJ25455.1 - 6e-14 51.4 0.4 1.7e-06 27.5 0.1 3.1 3 0 0 3 3 3 2 SH3 domain RA PF00788.23 OAJ25455.1 - 6.5e-11 42.7 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 OAJ25455.1 - 6e-10 39.1 0.0 9.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ25455.1 - 2.2e-09 37.6 0.0 3.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 OAJ25455.1 - 8.8e-08 31.9 4.6 0.0052 16.6 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 OAJ25455.1 - 9.5e-05 22.0 1.3 0.14 11.9 0.0 2.8 2 1 0 2 2 2 2 Variant SH3 domain SAM_PNT PF02198.16 OAJ25455.1 - 0.24 11.4 0.0 0.94 9.5 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain RRM_1 PF00076.22 OAJ25456.1 - 1.8e-17 62.9 0.0 4.3e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ25456.1 - 0.037 14.1 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 OAJ25456.1 - 0.086 12.5 0.3 0.34 10.6 0.3 1.8 1 1 0 1 1 1 0 Ribonuclease B OB domain RRM_occluded PF16842.5 OAJ25456.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DbpA PF03880.15 OAJ25456.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_5 PF13893.6 OAJ25456.1 - 0.25 10.9 0.0 0.34 10.5 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_1 PF00078.27 OAJ25457.1 - 1.3e-11 44.5 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EIN3 PF04873.13 OAJ25457.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Ethylene insensitive 3 HSP70 PF00012.20 OAJ25458.1 - 6.6e-204 678.5 11.2 7.5e-204 678.3 11.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ25458.1 - 2.5e-17 62.7 0.1 4.2e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 OAJ25458.1 - 0.00033 19.8 0.4 0.013 14.5 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 OAJ25458.1 - 0.014 15.1 0.0 0.055 13.2 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 OAJ25458.1 - 0.033 13.5 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Zincin-like metallopeptidase DUF3160 PF11369.8 OAJ25458.1 - 0.079 11.4 0.8 0.14 10.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Seryl_tRNA_N PF02403.22 OAJ25458.1 - 0.73 10.1 13.3 2.1 8.6 6.3 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TRAF_BIRC3_bd PF16673.5 OAJ25458.1 - 2.9 7.8 6.9 4.3 7.2 0.4 3.5 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain FliJ PF02050.16 OAJ25458.1 - 5.4 7.3 8.5 9.9 6.4 0.5 2.9 2 1 0 3 3 3 0 Flagellar FliJ protein Com_YlbF PF06133.11 OAJ25458.1 - 7.5 7.2 8.4 2.1 9.0 4.5 2.0 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Spectrin PF00435.21 OAJ25458.1 - 7.7 7.1 10.5 16 6.1 0.9 2.8 2 1 1 3 3 3 0 Spectrin repeat Phage_integrase PF00589.22 OAJ25492.1 - 0.00021 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Phage integrase family DUF1670 PF07900.11 OAJ25492.1 - 0.051 12.9 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) RT_RNaseH_2 PF17919.1 OAJ25492.1 - 0.14 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase DUF3504 PF12012.8 OAJ25492.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) HbrB PF08539.11 OAJ25494.1 - 3.5e-27 95.5 0.0 3.5e-27 95.5 0.0 4.6 3 1 0 3 3 3 1 HbrB-like Spt20 PF12090.8 OAJ25494.1 - 0.021 14.4 20.2 1.6 8.3 15.1 2.6 2 0 0 2 2 2 0 Spt20 family Zip PF02535.22 OAJ25495.1 - 0.2 10.8 3.6 0.38 9.9 1.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Phasin_2 PF09361.10 OAJ25495.1 - 1.7 9.0 11.4 0.51 10.6 6.5 2.8 2 0 0 2 2 2 0 Phasin protein SDA1 PF05285.12 OAJ25495.1 - 4.4 6.6 16.0 0.23 10.9 2.6 2.5 3 0 0 3 3 3 0 SDA1 RRM_1 PF00076.22 OAJ25522.1 - 3.2e-24 84.5 0.0 6.5e-12 45.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 OAJ25522.1 - 1.4e-18 65.4 0.0 0.00019 21.0 0.0 5.6 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 OAJ25522.1 - 0.00031 20.6 0.0 0.33 10.8 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 OAJ25522.1 - 0.032 13.7 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA-recognition motif HTH_21 PF13276.6 OAJ25522.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain Spt20 PF12090.8 OAJ25522.1 - 1.4 8.5 21.6 0.34 10.5 13.6 2.2 2 0 0 2 2 2 0 Spt20 family tRNA-synt_1g PF09334.11 OAJ25523.1 - 5.5e-76 255.8 1.1 2.2e-61 207.8 0.2 4.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ25523.1 - 3.1e-11 42.3 0.0 9.3e-05 20.9 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 OAJ25523.1 - 3e-06 26.8 0.5 0.02 14.3 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Acyl-CoA_dh_C PF12806.7 OAJ25523.1 - 0.04 14.1 1.1 0.076 13.2 1.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like HLH PF00010.26 OAJ25525.1 - 2.5e-06 27.3 0.0 6.3e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Nop14 PF04147.12 OAJ25525.1 - 0.52 8.5 16.9 0.21 9.8 4.7 2.2 2 0 0 2 2 2 0 Nop14-like family Prothymosin PF03247.14 OAJ25525.1 - 0.54 10.7 26.0 0.25 11.8 9.1 2.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family RXT2_N PF08595.11 OAJ25525.1 - 0.6 10.1 9.7 2.4 8.2 1.8 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 OAJ25525.1 - 2.9 7.1 23.3 1.7 7.9 7.6 2.3 2 0 0 2 2 2 0 NOA36 protein Ribosomal_L27 PF01016.19 OAJ25557.1 - 2.4e-34 117.2 0.2 4.4e-34 116.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF1180 PF06679.12 OAJ25557.1 - 1.1 9.6 6.9 0.61 10.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TRP PF06011.12 OAJ25558.1 - 1.2e-68 231.9 1.8 1.9e-68 231.2 1.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 OAJ25558.1 - 5.7e-29 101.3 0.1 8.6e-29 100.7 0.1 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 OAJ25558.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 ML domain LapA_dom PF06305.11 OAJ25558.1 - 7.6 6.4 12.4 0.43 10.4 0.2 3.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Abhydrolase_3 PF07859.13 OAJ25559.1 - 1.6e-32 113.1 0.0 2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ25559.1 - 0.03 13.2 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 OAJ25559.1 - 0.084 12.4 0.1 7.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 OAJ25559.1 - 0.096 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 OAJ25559.1 - 0.23 11.0 0.6 2.2 7.9 0.2 2.5 2 1 0 2 2 2 0 Putative esterase TFIIA PF03153.13 OAJ25560.1 - 9.6e-50 170.8 7.5 3.8e-29 102.9 5.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PWWP PF00855.17 OAJ25561.1 - 2.1e-17 63.3 0.1 2.1e-17 63.3 0.1 2.1 2 1 0 2 2 2 1 PWWP domain YL1 PF05764.13 OAJ25561.1 - 0.1 12.7 15.9 0.14 12.2 15.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Hid1 PF12722.7 OAJ25561.1 - 0.15 10.2 9.3 0.18 9.9 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4551 PF15087.6 OAJ25561.1 - 9.1 5.0 7.2 11 4.7 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 OAJ25561.1 - 9.2 4.4 14.2 11 4.1 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RhoGEF PF00621.20 OAJ25585.1 - 1.3e-25 90.7 0.5 1.3e-25 90.7 0.5 1.7 2 0 0 2 2 2 1 RhoGEF domain SKN1 PF03935.15 OAJ25588.1 - 3.5e-175 583.2 0.7 4.1e-175 583.0 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Herpes_U59 PF04529.12 OAJ25617.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein DUF494 PF04361.13 OAJ25618.1 - 0.045 13.6 0.1 0.086 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) ANAPC5 PF12862.7 OAJ25618.1 - 0.057 13.5 0.3 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Imm6 PF14434.6 OAJ25618.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 Lon_C PF05362.13 OAJ25620.1 - 2.6e-05 23.9 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain OAM_dimer PF16554.5 OAJ25621.1 - 0.4 11.2 0.0 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Rhodanese PF00581.20 OAJ25651.1 - 1.4e-12 48.0 0.0 5.9e-12 46.1 0.0 1.9 1 1 1 2 2 2 1 Rhodanese-like domain Nup188 PF10487.9 OAJ25652.1 - 1.1e-24 86.6 0.0 3e-11 42.0 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 MFS_1 PF07690.16 OAJ25653.1 - 1.5e-29 103.0 24.7 1.5e-29 103.0 24.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ25653.1 - 7.8e-20 71.2 15.7 9.4e-19 67.6 4.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 OAJ25653.1 - 0.027 13.3 6.8 0.015 14.2 1.4 2.8 2 1 0 2 2 2 0 MFS_1 like family SET PF00856.28 OAJ25675.1 - 2.6e-06 27.9 0.0 0.00013 22.4 0.0 2.7 1 1 0 1 1 1 1 SET domain PAP1 PF08601.10 OAJ25675.1 - 0.16 11.7 4.5 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 CENP-B_dimeris PF09026.10 OAJ25676.1 - 6.2 7.3 10.7 2 8.9 6.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M16_M PF16187.5 OAJ25677.1 - 7.1e-86 288.0 0.0 1.2e-85 287.2 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 OAJ25677.1 - 3.5e-41 140.6 0.1 2.8e-40 137.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ25677.1 - 5.7e-35 121.0 0.1 3.9e-20 72.6 0.0 3.7 4 1 0 4 4 4 2 Peptidase M16 inactive domain Coagulin PF02035.15 OAJ25677.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Coagulin Integrase_H2C2 PF17921.1 OAJ25709.1 - 5.2e-15 55.3 0.0 1.2e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 OAJ25709.1 - 1.8e-13 50.4 0.1 4e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ25709.1 - 4.4e-12 46.2 0.0 1.4e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 OAJ25709.1 - 9.1e-11 41.7 0.1 1.4e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ25709.1 - 0.038 14.3 0.1 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ25710.1 - 1.6e-17 63.4 0.0 3.5e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ25710.1 - 3.3e-16 59.5 0.0 1.2e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 OAJ25710.1 - 9.9e-16 57.9 0.0 2.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ25710.1 - 9.1e-15 54.5 0.3 1.7e-14 53.6 0.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ25710.1 - 1.1e-08 35.5 0.0 2.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ25710.1 - 2e-08 34.8 0.0 4.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ25710.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease PF09668.10 OAJ25710.1 - 3.5e-05 23.6 0.1 6.8e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Phage_integrase PF00589.22 OAJ25710.1 - 0.0029 17.4 0.9 0.0061 16.4 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family RVP PF00077.20 OAJ25710.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP_2 PF08284.11 OAJ25710.1 - 0.077 12.8 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Retroviral aspartyl protease DDE_Tnp_IS240 PF13610.6 OAJ25710.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 DDE domain SecY PF00344.20 OAJ25745.1 - 9.9e-75 251.6 7.3 1.2e-74 251.3 7.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 OAJ25745.1 - 8.9e-17 60.6 0.3 2.5e-16 59.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p Proton_antipo_N PF00662.20 OAJ25745.1 - 0.087 12.9 0.4 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Claudin_3 PF06653.11 OAJ25745.1 - 0.97 9.4 5.2 1.5 8.7 0.0 3.3 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Glyco_hydro_79C PF16862.5 OAJ25746.1 - 6.4e-14 52.7 0.2 1.4e-13 51.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain BH3 PF15285.6 OAJ25746.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting PTPA PF03095.15 OAJ25747.1 - 2.4e-96 322.7 0.0 3e-96 322.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Bd3614-deam PF14439.6 OAJ25747.1 - 0.14 12.2 2.1 0.37 10.9 2.1 1.7 1 0 0 1 1 1 0 Bd3614-like deaminase DUF659 PF04937.15 OAJ25779.1 - 7.8e-14 51.8 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.14 OAJ25779.1 - 0.00019 21.2 0.0 0.00052 19.8 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DHQ_synthase PF01761.20 OAJ25780.1 - 0.00045 19.5 0.0 0.00081 18.6 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase Ion_trans PF00520.31 OAJ25811.1 - 7.2e-10 38.5 8.5 8.2e-09 35.0 8.5 2.1 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 OAJ25811.1 - 1.1e-05 24.3 10.8 0.001 17.9 4.9 2.5 3 0 0 3 3 3 2 Polycystin cation channel Yip1 PF04893.17 OAJ25811.1 - 0.05 13.3 7.0 0.79 9.4 5.1 2.4 2 0 0 2 2 2 0 Yip1 domain DUF1929 PF09118.11 OAJ25812.1 - 1.3e-20 73.5 0.1 2.4e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 OAJ25812.1 - 2e-20 73.0 0.3 9.1e-13 48.0 0.0 4.2 4 0 0 4 4 4 3 Glyoxal oxidase N-terminus Septin PF00735.18 OAJ25813.1 - 3.1e-06 26.7 0.3 3.4e-06 26.5 0.3 1.1 1 0 0 1 1 1 1 Septin Vps16_C PF04840.12 OAJ25814.1 - 1.4e-07 30.9 0.3 0.0042 16.2 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region K_channel_TID PF07941.11 OAJ25814.1 - 0.00075 19.9 11.7 0.00075 19.9 11.7 2.3 2 0 0 2 2 2 1 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.7 OAJ25815.1 - 0.06 13.3 0.1 0.2 11.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like Phyto_Pns9_10 PF05878.11 OAJ25815.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 STE2 PF02116.15 OAJ25817.1 - 0.00014 21.2 3.2 0.00027 20.3 3.2 1.4 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR ANTH PF07651.16 OAJ25818.1 - 5.4e-48 163.4 0.0 7.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 OAJ25818.1 - 3.9e-05 23.7 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 ENTH domain 2OG-FeII_Oxy_3 PF13640.6 OAJ25846.1 - 3.3e-05 24.7 0.2 8.1e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Med12 PF09497.10 OAJ25875.1 - 2.3e-25 88.6 0.0 8.5e-25 86.8 0.0 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 ARPC4 PF05856.12 OAJ25876.1 - 4.3e-80 267.2 3.9 4.8e-80 267.0 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) CBP4 PF07960.11 OAJ25877.1 - 1.1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 OAJ25877.1 - 0.00042 20.2 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 HMG_CoA_synt_N PF01154.17 OAJ25878.1 - 1.3e-83 279.1 0.3 2.4e-83 278.3 0.3 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 OAJ25878.1 - 1.2e-82 277.7 0.0 1.6e-82 277.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal PEHE PF15275.6 OAJ25879.1 - 0.15 12.6 2.5 0.17 12.5 2.5 1.1 1 0 0 1 1 1 0 PEHE domain DUF3099 PF11298.8 OAJ25879.1 - 5.5 7.2 0.0 5.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) adh_short_C2 PF13561.6 OAJ25880.1 - 2.1e-08 34.0 0.1 2.9e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ25880.1 - 2.1e-08 33.9 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ25880.1 - 2.6e-05 24.2 0.0 3.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Helitron_like_N PF14214.6 OAJ25881.1 - 1.4e-24 87.4 0.0 3.6e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ25881.1 - 7.1e-21 74.8 0.1 2.8e-20 72.8 0.1 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ25881.1 - 4.1e-14 52.7 0.3 2.1e-13 50.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ25881.1 - 8e-08 32.7 0.1 5.8e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ25881.1 - 0.0016 18.8 0.2 0.0071 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ25881.1 - 0.22 11.5 0.4 2.9 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Histone PF00125.24 OAJ25908.1 - 8e-45 152.4 0.3 9.2e-45 152.2 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ25908.1 - 0.00016 22.0 0.1 0.00025 21.4 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ25908.1 - 0.00016 21.8 0.2 0.00025 21.1 0.2 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ25908.1 - 0.1 12.9 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 OAJ25908.1 - 0.14 12.8 0.9 0.17 12.5 0.9 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain preATP-grasp_3 PF18301.1 OAJ25909.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 pre ATP-grasp 3 domain zf-BED PF02892.15 OAJ25910.1 - 0.002 18.1 1.8 0.0049 16.9 1.8 1.6 1 0 0 1 1 1 1 BED zinc finger KDZ PF18758.1 OAJ25912.1 - 4.4e-40 137.6 0.0 1.9e-35 122.5 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ25912.1 - 9.5e-07 28.9 0.1 2.8e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ25912.1 - 0.00015 21.9 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Dmrt1 PF12374.8 OAJ25913.1 - 0.013 16.0 4.6 0.042 14.3 4.6 1.7 1 1 0 1 1 1 0 Double-sex mab3 related transcription factor 1 PS_Dcarbxylase PF02666.15 OAJ25937.1 - 1.3e-50 171.8 0.0 2.2e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 OAJ25937.1 - 5.7e-32 110.1 0.0 5.9e-17 61.8 0.0 4.0 3 1 0 3 3 3 3 C2 domain EF-hand_6 PF13405.6 OAJ25937.1 - 0.059 13.3 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain CNDH2_C PF16858.5 OAJ25937.1 - 0.19 11.6 4.2 0.4 10.5 0.4 2.3 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BNIP2 PF12496.8 OAJ25937.1 - 0.26 11.7 14.0 0.4 11.1 7.8 2.8 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC45 PF02724.14 OAJ25937.1 - 0.63 8.3 13.2 0.037 12.3 6.5 1.9 2 0 0 2 2 2 0 CDC45-like protein Ribosomal_60s PF00428.19 OAJ25938.1 - 0.17 12.5 1.8 0.37 11.4 1.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DASH_Dam1 PF08653.10 OAJ25968.1 - 1.1e-18 66.8 0.2 1.7e-18 66.1 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 Sen15 PF09631.10 OAJ25969.1 - 2.6e-11 43.7 0.0 9.8e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein CTU2 PF10288.9 OAJ25970.1 - 7.7e-18 64.8 0.3 7.7e-18 64.8 0.3 2.3 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 MIP PF00230.20 OAJ25971.1 - 4e-36 124.8 11.6 5.4e-36 124.4 11.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein PTPS_related PF10131.9 OAJ25971.1 - 0.033 12.5 0.5 0.052 11.9 0.5 1.2 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein FixQ PF05545.11 OAJ25971.1 - 0.17 11.8 1.5 0.56 10.2 1.5 1.9 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ RCC1 PF00415.18 OAJ25972.1 - 1.4e-21 76.8 13.3 2.3e-05 24.9 1.0 7.0 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ25972.1 - 7.1e-14 51.2 30.4 7.6e-11 41.5 0.4 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Helicase_C_2 PF13307.6 OAJ25973.1 - 2.4e-36 125.5 0.0 3.4e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain NADH_dehy_S2_C PF06444.11 OAJ25973.1 - 0.15 12.6 1.8 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus SE PF08491.10 OAJ26005.1 - 1e-80 270.8 0.0 7.2e-37 126.9 0.0 3.2 3 0 0 3 3 3 3 Squalene epoxidase DAO PF01266.24 OAJ26005.1 - 1.5e-11 44.5 0.9 4.6e-08 33.0 0.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ26005.1 - 2.4e-10 40.2 0.3 3.6e-06 26.5 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ26005.1 - 2.3e-05 24.5 0.9 6e-05 23.2 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ26005.1 - 0.00063 18.9 2.2 0.0023 17.1 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 OAJ26005.1 - 0.00074 18.7 0.8 0.0011 18.2 0.4 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 OAJ26005.1 - 0.00095 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 OAJ26005.1 - 0.00098 18.8 0.2 0.0023 17.6 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ26005.1 - 0.0012 18.7 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ26005.1 - 0.0013 18.1 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAJ26005.1 - 0.0015 18.0 1.4 0.0027 17.1 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ26005.1 - 0.002 18.6 0.2 0.0071 16.9 0.1 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 OAJ26005.1 - 0.0026 16.7 0.8 0.024 13.5 0.2 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Rossmann-like PF10727.9 OAJ26005.1 - 0.0063 16.4 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAJ26005.1 - 0.0086 16.3 0.1 0.016 15.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 OAJ26005.1 - 0.029 14.4 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 OAJ26005.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.15 OAJ26005.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 OAJ26005.1 - 0.23 11.5 0.0 0.42 10.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAJ26005.1 - 0.36 9.8 1.8 0.41 9.6 0.4 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Brix PF04427.18 OAJ26006.1 - 1.7e-42 145.7 0.0 2.1e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1654 PF07867.11 OAJ26007.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) CSN7a_helixI PF18392.1 OAJ26008.1 - 4.3e-05 23.3 0.2 7e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 OAJ26008.1 - 0.1 13.1 0.1 0.34 11.4 0.1 1.9 1 1 0 1 1 1 0 PCI domain DUF3767 PF12597.8 OAJ26009.1 - 1.3e-27 95.5 0.1 1.6e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) XRN_M PF17846.1 OAJ26010.1 - 3.1e-145 484.5 0.3 3.4e-108 362.4 0.0 2.5 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 OAJ26010.1 - 5.7e-100 333.7 0.0 1.1e-99 332.8 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 OAJ26010.1 - 0.00069 19.6 2.4 0.0016 18.4 2.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Antistasin PF02822.14 OAJ26010.1 - 0.22 12.2 1.1 2 9.1 0.7 2.4 2 0 0 2 2 2 0 Antistasin family Pkinase_Tyr PF07714.17 OAJ26012.1 - 0.00089 18.6 0.1 0.17 11.2 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ26012.1 - 0.0013 18.2 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 OAJ26012.1 - 0.0045 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ26012.1 - 0.01 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 OAJ26012.1 - 0.056 12.2 0.0 0.086 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GP67 PF17634.2 OAJ26012.1 - 0.32 11.4 6.2 0.74 10.3 6.2 1.5 1 0 0 1 1 1 0 Gene product 67 Na_Ca_ex PF01699.24 OAJ26045.1 - 1.2e-18 67.5 36.4 5.3e-11 42.7 17.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 OAJ26045.1 - 1.7e-15 57.4 3.8 1.7e-15 57.4 3.8 3.7 3 0 0 3 3 3 1 Inner membrane component domain DUF4906 PF16249.5 OAJ26045.1 - 0.68 9.7 2.8 1.5 8.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4906) SLATT_5 PF18160.1 OAJ26045.1 - 2.8 7.2 3.6 4.9 6.4 2.3 2.1 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DEAD PF00270.29 OAJ26047.1 - 2.5e-48 164.2 0.1 4.2e-47 160.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ26047.1 - 1.2e-29 102.9 0.0 1.8e-28 99.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Glyco_hydro_2 PF00703.21 OAJ26047.1 - 0.21 12.3 1.1 0.9 10.2 1.1 2.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Ctf8 PF09696.10 OAJ26048.1 - 4e-05 24.0 2.2 0.00011 22.5 2.2 1.9 1 1 0 1 1 1 1 Ctf8 Nop14 PF04147.12 OAJ26048.1 - 0.0031 15.8 11.6 0.0034 15.7 11.6 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ26048.1 - 0.009 15.5 14.5 0.0092 15.4 14.5 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 OAJ26048.1 - 0.011 15.2 10.0 0.011 15.1 10.0 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 OAJ26048.1 - 0.011 14.0 13.1 0.013 13.8 13.1 1.0 1 0 0 1 1 1 0 CDC45-like protein BNIP2 PF12496.8 OAJ26048.1 - 0.061 13.8 11.5 0.085 13.3 11.5 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CDC27 PF09507.10 OAJ26048.1 - 0.21 10.9 12.2 0.32 10.4 12.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YL1 PF05764.13 OAJ26048.1 - 0.21 11.6 14.6 0.26 11.4 14.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 OAJ26048.1 - 2 7.7 13.1 2.4 7.5 13.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mpp10 PF04006.12 OAJ26048.1 - 3.7 5.9 16.4 4.7 5.5 16.4 1.0 1 0 0 1 1 1 0 Mpp10 protein SURF2 PF05477.11 OAJ26048.1 - 4.9 6.8 12.9 6.2 6.4 12.9 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) eIF-3c_N PF05470.12 OAJ26048.1 - 8.5 4.6 7.9 9.6 4.4 7.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MMM1 PF10296.9 OAJ26049.1 - 3.8e-09 36.0 1.3 0.0017 17.4 0.0 3.6 3 1 0 4 4 4 3 Maintenance of mitochondrial morphology protein 1 DUF4366 PF14283.6 OAJ26049.1 - 0.0081 16.2 0.0 0.053 13.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF2052 PF09747.9 OAJ26049.1 - 0.1 12.8 12.2 1.2 9.2 7.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 OAJ26049.1 - 0.32 10.6 7.2 3.1 7.4 0.1 2.3 2 0 0 2 2 2 0 FAM176 family BSP_II PF05432.11 OAJ26049.1 - 1.4 8.5 9.7 3.7 7.2 0.6 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 OAJ26049.1 - 1.8 6.7 7.6 0.29 9.4 0.5 2.0 2 0 0 2 2 2 0 CDC45-like protein TPR_2 PF07719.17 OAJ26050.1 - 2e-10 39.9 19.3 0.21 11.8 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ26050.1 - 1.5e-08 34.1 9.6 0.33 10.9 0.4 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ26050.1 - 3.8e-08 33.5 22.2 0.015 15.6 1.9 7.8 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ26050.1 - 1e-07 32.2 29.7 0.35 11.8 0.5 10.8 10 1 2 12 12 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ26050.1 - 3e-06 27.8 24.5 0.018 15.7 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ26050.1 - 9.9e-06 25.2 11.1 4.5 7.5 0.4 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat BTAD PF03704.17 OAJ26050.1 - 2.5e-05 24.7 10.4 0.0058 17.1 0.8 3.6 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_19 PF14559.6 OAJ26050.1 - 2.8e-05 24.6 18.6 0.00015 22.2 1.1 6.0 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ26050.1 - 0.00016 22.1 18.0 0.8 10.5 0.3 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ26050.1 - 0.0005 20.2 15.0 0.22 11.7 2.6 6.6 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ26050.1 - 0.0022 18.1 6.5 0.51 10.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ26050.1 - 0.0099 16.2 0.2 5.7 7.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ26050.1 - 0.01 16.0 0.4 0.01 16.0 0.4 5.1 5 2 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 OAJ26050.1 - 0.05 14.3 9.7 0.93 10.3 0.1 5.8 6 0 0 6 6 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 OAJ26050.1 - 0.051 13.2 0.9 1.4 8.6 0.2 2.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 OAJ26050.1 - 0.067 13.1 14.3 5 7.1 0.7 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ26050.1 - 0.097 13.0 8.0 1.1 9.7 0.2 5.3 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ26050.1 - 0.6 9.8 6.6 6.9 6.4 0.2 4.4 5 0 0 5 5 5 0 TPR repeat DPBB_1 PF03330.18 OAJ26052.1 - 0.034 14.4 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Barwin PF00967.17 OAJ26052.1 - 0.04 13.8 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Barwin family RVT_1 PF00078.27 OAJ26078.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 OAJ26078.1 - 0.069 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RVT_3 PF13456.6 OAJ26078.1 - 0.075 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Phage_integrase PF00589.22 OAJ26079.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.6 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ26079.1 - 0.0067 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 OAJ26079.1 - 0.034 14.6 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3440 PF11922.8 OAJ26079.1 - 0.083 12.6 0.0 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Lon_C PF05362.13 OAJ26080.1 - 1e-64 217.9 0.1 1.8e-64 217.1 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 OAJ26080.1 - 1.3e-22 80.6 0.0 3.3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 OAJ26080.1 - 1.5e-09 37.9 0.0 1.1e-08 35.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 OAJ26080.1 - 4.4e-08 33.0 0.0 9.1e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase LON_substr_bdg PF02190.16 OAJ26080.1 - 4.5e-07 30.0 0.0 1.6e-06 28.2 0.0 1.9 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_16 PF13191.6 OAJ26080.1 - 3.7e-05 24.2 0.1 3.7e-05 24.2 0.1 2.8 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 OAJ26080.1 - 0.00056 20.2 0.2 0.013 15.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ26080.1 - 0.00073 19.7 0.0 0.0036 17.4 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ26080.1 - 0.0035 17.5 0.4 0.034 14.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ26080.1 - 0.0074 16.1 0.0 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ26080.1 - 0.018 14.4 0.0 0.051 13.0 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 OAJ26080.1 - 0.019 15.5 0.0 0.061 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ26080.1 - 0.026 14.9 0.0 0.061 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 OAJ26080.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 OAJ26080.1 - 0.041 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_PrkA PF08298.11 OAJ26080.1 - 0.042 12.8 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain TniB PF05621.11 OAJ26080.1 - 0.049 13.0 0.3 5.4 6.4 0.0 3.4 4 0 0 4 4 4 0 Bacterial TniB protein AAA_25 PF13481.6 OAJ26080.1 - 0.071 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cut8 PF08559.10 OAJ26080.1 - 0.078 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein NACHT PF05729.12 OAJ26080.1 - 0.087 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain TelA PF05816.11 OAJ26080.1 - 0.15 11.1 0.8 0.29 10.1 0.8 1.4 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) AAA_7 PF12775.7 OAJ26080.1 - 0.15 11.5 0.1 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ26080.1 - 0.18 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain GREB1 PF15782.5 OAJ26080.1 - 0.2 8.8 0.0 0.28 8.2 0.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer KTI12 PF08433.10 OAJ26080.1 - 0.2 11.1 0.0 0.42 10.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_23 PF13476.6 OAJ26080.1 - 0.88 10.0 0.0 0.88 10.0 0.0 2.7 2 1 1 3 3 2 0 AAA domain SQS_PSY PF00494.19 OAJ26113.1 - 1.9e-32 112.8 0.2 5.7e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 Squalene/phytoene synthase Alk_phosphatase PF00245.20 OAJ26114.1 - 2.6e-73 247.3 0.4 3.2e-73 247.1 0.4 1.0 1 0 0 1 1 1 1 Alkaline phosphatase TPM_phosphatase PF04536.14 OAJ26114.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 TPM domain Glutaredoxin PF00462.24 OAJ26115.1 - 2.5e-18 66.0 0.0 3.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OAJ26115.1 - 0.00017 22.0 0.0 0.00022 21.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ26115.1 - 0.00075 19.9 0.1 0.0016 18.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_2 PF13409.6 OAJ26115.1 - 0.0023 18.2 0.0 0.0031 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TraF PF13728.6 OAJ26115.1 - 0.0093 15.8 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein GST_N_3 PF13417.6 OAJ26115.1 - 0.015 15.7 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.6 OAJ26115.1 - 0.052 13.7 0.6 1.6 8.8 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.6 OAJ26115.1 - 0.055 13.6 0.0 0.084 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 OAJ26115.1 - 0.07 12.9 0.1 0.35 10.6 0.1 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AAA PF00004.29 OAJ26116.1 - 6.1e-41 139.9 0.0 1.3e-40 138.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ26116.1 - 1.3e-06 28.1 0.1 3.5e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 OAJ26116.1 - 4.2e-05 23.6 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ26116.1 - 9.2e-05 22.7 0.0 0.0047 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ26116.1 - 0.00024 21.2 0.0 0.00083 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ26116.1 - 0.00089 19.7 0.8 0.022 15.2 0.1 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 OAJ26116.1 - 0.0016 17.6 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 OAJ26116.1 - 0.0076 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 OAJ26116.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ26116.1 - 0.018 14.6 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ26116.1 - 0.019 15.1 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ26116.1 - 0.048 13.5 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAJ26116.1 - 0.056 12.8 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 OAJ26116.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 OAJ26116.1 - 0.074 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ26116.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ26116.1 - 0.088 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 OAJ26116.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 OAJ26116.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase YjcB PF15940.5 OAJ26117.1 - 0.072 13.3 1.7 0.45 10.7 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function DUF3598 PF12204.8 OAJ26118.1 - 0.26 10.7 0.0 19 4.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) RSN1_7TM PF02714.15 OAJ26119.1 - 4.4e-70 236.1 22.8 1e-69 234.9 22.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ26119.1 - 2.3e-36 125.6 0.0 4.4e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ26119.1 - 4.5e-36 124.0 0.9 4.5e-36 124.0 0.9 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport Sm_multidrug_ex PF06695.11 OAJ26119.1 - 0.14 12.8 0.0 0.14 12.8 0.0 4.1 6 1 1 7 7 7 0 Putative small multi-drug export protein Baculo_11_kDa PF06143.11 OAJ26119.1 - 1 9.0 3.2 1.5 8.4 0.4 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family TFIIA PF03153.13 OAJ26120.1 - 1e-06 29.1 0.2 2.2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3318 PF11780.8 OAJ26120.1 - 0.16 11.9 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Pcc1 PF09341.10 OAJ26153.1 - 1.4e-18 66.7 1.5 1.7e-18 66.5 1.5 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF3323 PF11796.8 OAJ26156.1 - 6.3e-05 23.0 0.4 6.3e-05 23.0 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) Eclosion PF04736.12 OAJ26156.1 - 0.021 14.5 0.5 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 Eclosion hormone E3_binding PF02817.17 OAJ26156.1 - 0.11 12.9 0.9 23 5.4 0.1 3.3 3 0 0 3 3 3 0 e3 binding domain Glyco_hydro_9 PF00759.19 OAJ26156.1 - 0.13 11.6 11.0 0.63 9.4 3.5 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 GATA PF00320.27 OAJ26157.1 - 0.00019 20.9 2.1 0.00031 20.3 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Rod_cone_degen PF15201.6 OAJ26157.1 - 0.14 12.2 0.9 0.45 10.7 0.1 2.3 3 0 0 3 3 3 0 Progressive rod-cone degeneration T2SSM PF04612.12 OAJ26157.1 - 2.8 8.0 6.0 0.54 10.3 2.6 1.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M NAM-associated PF14303.6 OAJ26157.1 - 5.7 7.6 8.3 0.78 10.4 0.6 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain IML1 PF12257.8 OAJ26187.1 - 3.4e-113 377.5 0.0 4.5e-113 377.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 GST_N_3 PF13417.6 OAJ26188.1 - 0.00035 20.9 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF1365 PF07103.11 OAJ26189.1 - 2.4e-53 181.3 0.0 3.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) HLH PF00010.26 OAJ26190.1 - 3.1e-16 59.1 0.1 6.6e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ribosomal_60s PF00428.19 OAJ26190.1 - 0.0027 18.2 3.5 0.0027 18.2 3.5 6.5 6 0 0 6 6 6 1 60s Acidic ribosomal protein ECH_1 PF00378.20 OAJ26222.1 - 4.3e-40 137.6 0.9 2.3e-20 73.0 0.1 3.8 3 1 0 4 4 4 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ26222.1 - 1.2e-21 77.6 0.2 1.1e-10 41.6 0.0 2.8 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase AA_permease PF00324.21 OAJ26223.1 - 1.6e-134 449.1 37.4 1.9e-134 448.9 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ26223.1 - 8.2e-42 143.5 41.6 1.1e-41 143.1 41.6 1.2 1 0 0 1 1 1 1 Amino acid permease FHA PF00498.26 OAJ26224.1 - 9e-05 22.8 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF3402 PF11882.8 OAJ26225.1 - 4.6e-120 401.9 0.0 1.1e-115 387.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3402) N1221 PF07923.13 OAJ26225.1 - 1.5e-60 204.8 0.0 3.3e-60 203.7 0.0 1.5 1 1 0 1 1 1 1 N1221-like protein DPBB_1 PF03330.18 OAJ26227.1 - 0.066 13.5 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 Lytic transglycolase DUF5494 PF17598.2 OAJ26228.1 - 0.23 11.6 0.6 0.38 10.9 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Trypan_PARP PF05887.11 OAJ26228.1 - 1 9.3 12.3 1.6 8.7 12.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) tRNA_bind PF01588.20 OAJ26259.1 - 8.5e-27 93.1 0.0 1.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 OAJ26259.1 - 9.6e-05 22.5 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ26259.1 - 0.0076 16.2 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ26259.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aa_trans PF01490.18 OAJ26260.1 - 6.7e-07 28.4 0.5 0.0036 16.1 2.4 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Yip1 PF04893.17 OAJ26260.1 - 0.22 11.2 0.0 0.22 11.2 0.0 4.1 5 0 0 5 5 5 0 Yip1 domain COPI_C PF06957.11 OAJ26260.1 - 3.6 6.2 5.8 6.1 5.5 5.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ABC_tran PF00005.27 OAJ26261.1 - 5.8e-37 127.3 1.4 1.3e-19 71.1 0.0 3.9 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.19 OAJ26261.1 - 6.2e-08 32.4 1.9 0.33 10.4 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ26261.1 - 6.8e-07 29.4 7.1 0.0092 15.8 0.0 4.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 OAJ26261.1 - 8.9e-06 25.7 3.6 8.9e-06 25.7 3.6 2.6 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 OAJ26261.1 - 2.4e-05 24.0 0.3 0.052 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ26261.1 - 2.8e-05 24.1 0.5 0.0083 16.0 0.2 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 OAJ26261.1 - 0.0009 19.8 7.7 0.4 11.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 OAJ26261.1 - 0.0017 18.4 0.4 0.26 11.4 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 OAJ26261.1 - 0.0041 17.3 0.0 0.074 13.3 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit HopA1 PF17914.1 OAJ26261.1 - 0.016 14.9 0.6 0.067 13.0 0.1 2.1 2 0 0 2 2 2 0 HopA1 effector protein family MeaB PF03308.16 OAJ26261.1 - 0.017 14.1 1.1 0.06 12.3 0.4 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 OAJ26261.1 - 0.026 14.5 0.1 1.1 9.1 0.0 3.4 4 0 0 4 4 4 0 NTPase RNA_helicase PF00910.22 OAJ26261.1 - 0.053 13.9 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 OAJ26261.1 - 0.063 13.2 0.0 16 5.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 OAJ26261.1 - 0.082 12.5 0.7 5.7 6.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 OAJ26261.1 - 0.12 12.4 0.7 19 5.2 0.0 3.8 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) DUF1515 PF07439.11 OAJ26261.1 - 0.14 12.2 1.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) AAA_7 PF12775.7 OAJ26261.1 - 0.14 11.6 0.0 0.93 9.0 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ26261.1 - 0.71 10.2 5.7 0.44 10.9 0.2 3.2 2 2 0 2 2 2 0 AAA ATPase domain MRFAP1 PF15155.6 OAJ26261.1 - 5.9 7.4 11.7 0.5 10.9 0.6 3.1 3 0 0 3 3 2 0 MORF4 family-associated protein1 tRNA-synt_1e PF01406.19 OAJ26262.1 - 0.62 9.3 2.9 0.92 8.8 2.9 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TORC_M PF12885.7 OAJ26262.1 - 5.7 6.8 6.4 3.5 7.5 0.3 2.7 3 0 0 3 3 3 0 Transducer of regulated CREB activity middle domain Nup96 PF12110.8 OAJ26295.1 - 3.4e-91 305.4 0.5 5.3e-91 304.8 0.5 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 OAJ26295.1 - 2.7e-50 170.4 0.0 4.5e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 OAJ26295.1 - 3.8e-25 88.5 227.1 3.2e-11 43.9 27.4 12.5 4 3 10 14 14 14 10 Nucleoporin FG repeat region PPP4R2 PF09184.11 OAJ26295.1 - 0.38 10.3 7.4 0.63 9.6 7.4 1.2 1 0 0 1 1 1 0 PPP4R2 Tub_N PF16322.5 OAJ26295.1 - 0.44 10.9 5.3 1.1 9.7 5.3 1.6 1 0 0 1 1 1 0 Tubby N-terminal NOA36 PF06524.12 OAJ26295.1 - 3.1 7.0 8.1 5.2 6.3 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein RCC1 PF00415.18 OAJ26296.1 - 5.3e-49 164.6 9.6 6.5e-07 29.9 0.0 8.7 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ26296.1 - 6.1e-32 108.8 29.6 2.8e-06 27.0 0.1 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Aldo_ket_red PF00248.21 OAJ26297.1 - 1.3e-42 146.0 0.2 1.5e-40 139.3 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MULE PF10551.9 OAJ26336.1 - 2.1e-10 40.9 0.9 1.2e-06 28.9 0.1 2.8 2 1 1 3 3 3 2 MULE transposase domain Peptidase_C48 PF02902.19 OAJ26336.1 - 6.5e-09 35.9 0.1 1.7e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain ADK PF00406.22 OAJ26338.1 - 2.8e-56 189.8 0.1 3.4e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 OAJ26338.1 - 8.4e-20 71.6 0.4 2.6e-19 70.0 0.1 1.8 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 OAJ26338.1 - 3e-16 59.1 0.0 6.6e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 OAJ26338.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ26338.1 - 0.0062 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 OAJ26338.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 OAJ26338.1 - 0.051 14.0 0.1 0.087 13.3 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ZapB PF06005.12 OAJ26339.1 - 0.005 17.3 2.8 0.01 16.3 2.8 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Rootletin PF15035.6 OAJ26339.1 - 0.017 15.1 0.3 0.028 14.4 0.3 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-H PF05837.12 OAJ26339.1 - 0.019 15.4 0.5 0.037 14.4 0.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ATG16 PF08614.11 OAJ26339.1 - 0.026 14.7 2.7 0.045 14.0 2.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 OAJ26339.1 - 0.055 13.0 0.4 0.097 12.2 0.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Tropomyosin PF00261.20 OAJ26339.1 - 0.057 12.8 3.6 0.086 12.2 3.6 1.1 1 0 0 1 1 1 0 Tropomyosin DHR10 PF18595.1 OAJ26339.1 - 0.11 12.6 3.6 0.18 11.8 3.6 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF773 PF05600.12 OAJ26339.1 - 0.22 10.2 0.3 0.31 9.7 0.3 1.1 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 ADIP PF11559.8 OAJ26339.1 - 0.26 11.4 2.5 0.43 10.7 2.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UQ_con PF00179.26 OAJ26340.1 - 3.9e-46 156.2 0.0 4.4e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ26340.1 - 6.1e-06 26.0 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ26340.1 - 0.049 13.9 1.7 0.095 13.0 1.7 1.6 1 1 0 1 1 1 0 RWD domain Tim17 PF02466.19 OAJ26341.1 - 4.2e-05 23.9 3.3 0.41 11.0 0.0 3.2 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 OAJ26341.1 - 0.0026 18.4 0.3 0.01 16.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 GATA PF00320.27 OAJ26342.1 - 1.2e-13 50.5 3.7 2.1e-13 49.6 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 OAJ26342.1 - 6e-07 29.5 0.0 6e-07 29.5 0.0 3.2 2 1 0 2 2 1 1 PAS fold PAS_3 PF08447.12 OAJ26342.1 - 8.4e-06 26.0 1.5 2e-05 24.8 0.0 2.2 2 0 0 2 2 1 1 PAS fold TFIIA PF03153.13 OAJ26342.1 - 0.00089 19.4 58.6 0.0017 18.4 58.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAJ26342.1 - 0.013 15.6 12.9 0.024 14.7 12.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 OAJ26342.1 - 0.013 14.3 14.7 0.021 13.6 14.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAS_4 PF08448.10 OAJ26342.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 1 0 PAS fold SRP-alpha_N PF04086.13 OAJ26342.1 - 0.019 14.9 21.2 0.026 14.4 18.2 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal TF_Zn_Ribbon PF08271.12 OAJ26342.1 - 0.023 14.2 0.4 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF572 PF04502.13 OAJ26342.1 - 0.024 14.3 16.1 0.041 13.5 16.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CCSAP PF15748.5 OAJ26342.1 - 0.04 14.1 26.9 0.097 12.8 26.9 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 OAJ26342.1 - 0.053 12.3 31.7 0.083 11.6 31.7 1.2 1 0 0 1 1 1 0 Presenilin ArfGap PF01412.18 OAJ26342.1 - 0.092 12.8 0.2 0.092 12.8 0.2 2.6 2 0 0 2 2 1 0 Putative GTPase activating protein for Arf V_ATPase_I PF01496.19 OAJ26342.1 - 0.14 10.1 20.8 0.21 9.5 20.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mem_trans PF03547.18 OAJ26342.1 - 0.14 10.5 0.2 0.17 10.3 0.2 1.1 1 0 0 1 1 1 0 Membrane transport protein PAS_9 PF13426.7 OAJ26342.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 1 0 PAS domain DUF4746 PF15928.5 OAJ26342.1 - 0.17 11.3 18.5 0.27 10.6 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) VIR_N PF15912.5 OAJ26342.1 - 0.26 10.9 10.2 0.55 9.8 10.2 1.6 1 0 0 1 1 1 0 Virilizer, N-terminal DUF4045 PF13254.6 OAJ26342.1 - 0.35 10.5 22.8 0.02 14.5 16.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Zip PF02535.22 OAJ26342.1 - 0.81 8.8 17.6 1.6 7.9 17.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 OAJ26342.1 - 1.1 7.9 16.1 2.2 6.9 16.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dapper PF15268.6 OAJ26342.1 - 1.8 7.3 28.8 2.8 6.7 28.8 1.2 1 0 0 1 1 1 0 Dapper MCM_bind PF09739.9 OAJ26342.1 - 2 6.8 25.1 2.9 6.2 25.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4471 PF14740.6 OAJ26342.1 - 3.6 6.7 16.4 7.6 5.7 16.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Lin-8 PF03353.15 OAJ26342.1 - 3.9 6.9 32.3 7 6.1 32.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sin_N PF04801.13 OAJ26342.1 - 5.8 6.0 39.1 9 5.4 39.1 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Dimer_Tnp_hAT PF05699.14 OAJ26378.1 - 1.1e-08 34.7 0.0 2.8e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MDM1 PF15501.6 OAJ26380.1 - 0.00099 18.4 19.8 0.0012 18.1 19.8 1.0 1 0 0 1 1 1 1 Nuclear protein MDM1 EPL1 PF10513.9 OAJ26380.1 - 0.0039 17.6 8.5 0.0041 17.5 8.5 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like Tim54 PF11711.8 OAJ26380.1 - 0.019 13.8 14.2 0.019 13.7 14.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5427 PF10310.9 OAJ26380.1 - 0.027 13.4 14.5 0.029 13.3 14.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Dynamin_N PF00350.23 OAJ26380.1 - 0.03 14.4 3.1 0.031 14.3 3.1 1.1 1 0 0 1 1 1 0 Dynamin family Bud13 PF09736.9 OAJ26380.1 - 0.032 14.6 18.8 0.043 14.2 18.8 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Presenilin PF01080.17 OAJ26380.1 - 0.036 12.9 16.7 0.035 12.9 16.7 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 OAJ26380.1 - 0.037 12.8 14.0 0.035 12.9 14.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 OAJ26380.1 - 0.048 12.6 18.9 0.051 12.5 18.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3807 PF12720.7 OAJ26380.1 - 0.056 13.7 21.0 0.064 13.5 21.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pkinase_fungal PF17667.1 OAJ26380.1 - 0.06 12.1 6.5 0.07 11.9 6.5 1.0 1 0 0 1 1 1 0 Fungal protein kinase UPF0560 PF10577.9 OAJ26380.1 - 0.063 11.8 16.0 0.065 11.7 16.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMR1 PF08505.10 OAJ26380.1 - 0.077 13.3 16.6 0.088 13.1 16.6 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SpoIIP PF07454.11 OAJ26380.1 - 0.078 12.4 17.8 0.089 12.2 17.8 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 OAJ26380.1 - 0.082 11.2 17.4 0.085 11.1 17.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 OAJ26380.1 - 0.095 12.9 10.2 0.1 12.7 10.2 1.1 1 0 0 1 1 1 0 DDHD domain SLC12 PF03522.15 OAJ26380.1 - 0.11 11.5 12.5 0.12 11.4 12.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SRP-alpha_N PF04086.13 OAJ26380.1 - 0.15 11.9 15.9 0.17 11.7 15.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 OAJ26380.1 - 0.23 11.3 20.2 0.25 11.1 20.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 OAJ26380.1 - 0.26 11.5 21.3 0.29 11.3 21.3 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MCD PF05292.11 OAJ26380.1 - 0.4 10.2 5.2 0.48 10.0 5.2 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF2828 PF11443.8 OAJ26380.1 - 0.45 8.6 17.7 0.54 8.3 17.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 OAJ26380.1 - 0.5 9.8 13.6 0.57 9.6 13.6 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 OAJ26380.1 - 0.52 8.5 23.7 0.56 8.4 23.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TAF4 PF05236.14 OAJ26380.1 - 0.52 10.0 20.3 0.6 9.8 20.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CPSF100_C PF13299.6 OAJ26380.1 - 0.58 10.3 15.7 0.79 9.9 15.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 OAJ26380.1 - 0.72 8.4 10.5 0.78 8.3 10.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator FAM60A PF15396.6 OAJ26380.1 - 0.78 9.7 11.8 0.89 9.5 11.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RPN2_C PF18004.1 OAJ26380.1 - 0.82 9.6 19.0 0.99 9.3 19.0 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Asp-B-Hydro_N PF05279.11 OAJ26380.1 - 0.86 9.6 15.6 1 9.4 15.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4746 PF15928.5 OAJ26380.1 - 0.88 8.9 15.2 1 8.7 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RNA_pol_Rpc4 PF05132.14 OAJ26380.1 - 0.93 9.9 16.4 1.1 9.6 16.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Spt20 PF12090.8 OAJ26380.1 - 0.96 9.0 35.2 1.3 8.6 35.2 1.2 1 0 0 1 1 1 0 Spt20 family BORG_CEP PF14957.6 OAJ26380.1 - 0.97 10.6 11.3 1.1 10.4 11.3 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF3408 PF11888.8 OAJ26380.1 - 1.1 9.4 19.0 1.6 8.8 19.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Hid1 PF12722.7 OAJ26380.1 - 1.2 7.2 14.3 1.2 7.2 14.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 OAJ26380.1 - 1.2 6.2 13.1 1.3 6.0 13.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PTPRCAP PF15713.5 OAJ26380.1 - 1.3 9.3 23.9 0.26 11.6 21.0 1.3 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated Lin-8 PF03353.15 OAJ26380.1 - 1.3 8.5 18.6 1.4 8.4 18.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DDRGK PF09756.9 OAJ26380.1 - 1.4 8.5 31.3 1.7 8.2 31.3 1.1 1 0 0 1 1 1 0 DDRGK domain MDM10 PF12519.8 OAJ26380.1 - 1.5 7.6 13.7 1.6 7.5 13.7 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TFIIA PF03153.13 OAJ26380.1 - 1.6 8.6 31.9 1.8 8.5 31.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.16 OAJ26380.1 - 1.7 8.1 14.2 1.9 7.9 14.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 OAJ26380.1 - 1.8 7.9 16.7 2 7.7 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.6 OAJ26380.1 - 1.8 8.2 13.5 2.5 7.7 13.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF4228 PF14009.6 OAJ26380.1 - 1.8 8.9 11.0 2.1 8.7 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CCDC53 PF10152.9 OAJ26380.1 - 2 8.8 16.5 2.6 8.4 16.5 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Afi1 PF07792.12 OAJ26380.1 - 2.1 8.9 16.9 2.9 8.4 16.9 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3584 PF12128.8 OAJ26380.1 - 2.3 5.6 22.6 2.4 5.6 22.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Neur_chan_memb PF02932.16 OAJ26380.1 - 2.9 7.9 13.4 3.1 7.8 13.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 OAJ26380.1 - 3 7.9 15.3 3.6 7.7 15.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family HSP70 PF00012.20 OAJ26380.1 - 3.2 5.8 11.9 3.3 5.8 11.9 1.0 1 0 0 1 1 1 0 Hsp70 protein TraV PF09676.10 OAJ26380.1 - 3.5 8.6 16.7 4.5 8.3 16.7 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Rtf2 PF04641.12 OAJ26380.1 - 3.7 6.8 17.8 4.5 6.6 17.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CobT PF06213.12 OAJ26380.1 - 3.9 6.8 29.7 4.9 6.4 29.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.8 OAJ26380.1 - 3.9 6.3 28.3 5.4 5.9 28.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Paf1 PF03985.13 OAJ26380.1 - 4.2 6.3 28.9 5.3 5.9 28.9 1.0 1 0 0 1 1 1 0 Paf1 Membralin PF09746.9 OAJ26380.1 - 4.2 6.3 9.5 4.7 6.2 9.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein DUF4637 PF15470.6 OAJ26380.1 - 4.5 7.0 16.0 5.9 6.6 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Borrelia_P83 PF05262.11 OAJ26380.1 - 4.7 5.6 19.6 5 5.5 19.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Med19 PF10278.9 OAJ26380.1 - 4.8 7.1 19.7 6.3 6.7 19.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S64 PF08192.11 OAJ26380.1 - 5 5.5 14.5 5.6 5.3 14.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2126 PF09899.9 OAJ26380.1 - 5.1 5.0 11.7 5.6 4.9 11.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF853 PF05872.12 OAJ26380.1 - 5.2 5.5 10.6 5.8 5.4 10.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PPL5 PF18168.1 OAJ26380.1 - 5.4 6.2 13.9 6.4 6.0 13.9 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Cellulose_synt PF03552.14 OAJ26380.1 - 5.6 5.3 6.9 6 5.2 6.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Plasmodium_Vir PF05795.11 OAJ26380.1 - 5.8 6.2 11.3 6.1 6.2 11.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MCM_bind PF09739.9 OAJ26380.1 - 5.9 5.2 18.2 6.7 5.0 18.2 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TERB2 PF15101.6 OAJ26380.1 - 6.3 6.8 20.4 7.8 6.5 20.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CLN3 PF02487.17 OAJ26380.1 - 6.8 5.6 13.7 7.9 5.4 13.7 1.0 1 0 0 1 1 1 0 CLN3 protein FHIPEP PF00771.20 OAJ26380.1 - 7 5.0 7.6 7.8 4.8 7.6 1.2 1 0 0 1 1 1 0 FHIPEP family MAJIN PF15077.6 OAJ26380.1 - 7.1 6.3 15.2 8.6 6.1 15.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein AAA_11 PF13086.6 OAJ26380.1 - 7.1 6.3 17.5 8.6 6.1 17.5 1.1 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.6 OAJ26380.1 - 7.4 4.3 33.4 7.7 4.3 33.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TRAP_alpha PF03896.16 OAJ26380.1 - 7.8 5.6 11.4 9.6 5.3 11.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FemAB PF02388.16 OAJ26380.1 - 8.8 5.1 18.2 11 4.8 18.2 1.0 1 0 0 1 1 1 0 FemAB family ATP11 PF06644.11 OAJ26380.1 - 9.6 5.9 19.8 12 5.6 19.8 1.1 1 0 0 1 1 1 0 ATP11 protein TFB6 PF17110.5 OAJ26380.1 - 9.6 5.9 13.5 12 5.6 13.5 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH ALMT PF11744.8 OAJ26380.1 - 9.8 4.9 14.1 11 4.7 14.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PA26 PF04636.13 OAJ26380.1 - 9.9 5.0 11.8 11 4.8 11.8 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF659 PF04937.15 OAJ26381.1 - 0.011 15.5 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Miga PF10265.9 OAJ26381.1 - 4.1 6.3 8.8 6.7 5.6 8.8 1.2 1 0 0 1 1 1 0 Mitoguardin RCC1 PF00415.18 OAJ26417.1 - 5.6e-11 42.9 1.1 0.14 12.8 0.0 6.8 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ26417.1 - 0.00039 20.1 14.3 0.12 12.2 1.0 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat TRAPPC9-Trs120 PF08626.11 OAJ26418.1 - 4.7e-156 521.2 0.0 1.3e-154 516.4 0.0 2.5 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Ank_4 PF13637.6 OAJ26419.1 - 2.5e-05 24.7 0.0 0.00014 22.4 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ26419.1 - 0.0013 19.3 0.0 0.0066 17.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ26419.1 - 0.0063 16.9 0.2 0.57 10.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 OAJ26419.1 - 0.049 14.2 0.1 1.2 9.9 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat NUDIX PF00293.28 OAJ26420.1 - 2.1e-11 44.0 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RVT_2 PF07727.14 OAJ26451.1 - 2.6e-66 223.7 0.0 4.1e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 OAJ26451.1 - 1.3e-20 73.5 0.2 2.4e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 OAJ26451.1 - 5e-14 52.5 0.0 3.7e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ26451.1 - 3.9e-10 39.4 0.1 1.2e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ26451.1 - 2.3e-07 30.6 1.6 5.3e-07 29.4 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle rve_3 PF13683.6 OAJ26451.1 - 0.068 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain zf-CCHC_6 PF15288.6 OAJ26451.1 - 0.31 10.9 3.8 0.69 9.8 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3018 PF11455.8 OAJ26452.1 - 0.095 12.6 0.8 0.23 11.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) SAP18 PF06487.12 OAJ26453.1 - 2.2e-13 50.6 0.0 3.5e-13 49.9 0.0 1.3 1 1 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) UPF0254 PF06787.11 OAJ26453.1 - 0.018 14.8 0.2 0.027 14.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Ribosomal_60s PF00428.19 OAJ26453.1 - 0.42 11.2 17.5 0.47 11.1 2.1 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF5320 PF17253.2 OAJ26453.1 - 1.2 10.2 0.0 1.2 10.2 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) ArAE_2 PF10334.9 OAJ26498.1 - 7.7e-45 153.5 0.1 1.3e-44 152.7 0.1 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 OAJ26498.1 - 1.2e-42 146.6 2.7 1.7e-41 142.8 2.7 2.4 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 OAJ26498.1 - 6e-06 26.4 29.2 8e-05 22.8 15.2 3.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like EpuA PF11772.8 OAJ26498.1 - 0.077 12.7 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta AATF-Che1 PF13339.6 OAJ26498.1 - 0.12 13.0 2.1 0.21 12.3 1.2 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor C2 PF00168.30 OAJ26499.1 - 8e-14 51.8 0.3 0.0012 19.1 0.1 3.5 2 1 1 3 3 3 3 C2 domain DDE_Tnp_1_6 PF13751.6 OAJ26499.1 - 0.2 11.9 0.4 0.48 10.6 0.4 1.7 1 0 0 1 1 1 0 Transposase DDE domain Alginate_lyase PF05426.12 OAJ26501.1 - 3e-49 168.0 6.0 3.6e-48 164.5 1.7 2.3 2 0 0 2 2 2 2 Alginate lyase ETF PF01012.21 OAJ26502.1 - 8.1e-44 149.7 9.5 1.4e-43 148.9 9.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 OAJ26502.1 - 6.2e-33 112.7 0.6 6.2e-33 112.7 0.6 2.2 3 0 0 3 3 3 1 Electron transfer flavoprotein FAD-binding domain BMC PF00936.19 OAJ26502.1 - 0.0065 16.4 1.6 0.0065 16.4 1.6 2.6 2 0 0 2 2 2 1 BMC domain CRAL_TRIO_N PF03765.15 OAJ26504.1 - 6.4e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 OAJ26504.1 - 0.0038 17.0 0.0 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Miga PF10265.9 OAJ26504.1 - 0.021 13.8 0.6 0.023 13.7 0.6 1.0 1 0 0 1 1 1 0 Mitoguardin INCENP_ARK-bind PF03941.15 OAJ26504.1 - 0.06 13.3 1.1 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region RNase_P_p30 PF01876.16 OAJ26505.1 - 5.2e-40 137.2 0.1 1.2e-37 129.5 0.0 3.0 3 0 0 3 3 3 1 RNase P subunit p30 CCDC117 PF15810.5 OAJ26505.1 - 0.31 11.3 4.0 0.56 10.5 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 SUIM_assoc PF16619.5 OAJ26505.1 - 2.1 8.5 22.9 0.43 10.7 13.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ABM PF03992.16 OAJ26551.1 - 0.35 11.0 3.5 0.15 12.2 0.3 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase RVT_3 PF13456.6 OAJ26552.1 - 0.034 14.0 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like MutL_C PF08676.11 OAJ26587.1 - 5.5e-22 78.1 0.1 3.5e-21 75.5 0.1 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 OAJ26587.1 - 6.6e-16 58.1 0.0 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ26587.1 - 1.4e-11 44.4 0.4 8e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ26587.1 - 1.1e-07 32.3 0.0 3.9e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C97 PF05903.14 OAJ26588.1 - 9.8e-38 129.4 0.0 2.7e-37 127.9 0.0 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain SRR1 PF07985.12 OAJ26588.1 - 2.2e-13 50.0 0.3 4.2e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 SRR1 PIF1 PF05970.14 OAJ26627.1 - 6.1e-20 71.7 0.0 8.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ26627.1 - 2.4e-14 53.5 0.0 5.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ26627.1 - 2.2e-09 37.8 0.0 7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ26627.1 - 0.00011 22.7 0.6 0.00027 21.3 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ26627.1 - 0.003 17.8 0.0 0.0084 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAJ26627.1 - 0.0043 16.9 1.0 1.5 8.5 0.0 2.6 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 OAJ26627.1 - 0.0065 16.0 0.1 0.27 10.7 0.0 2.4 1 1 1 2 2 2 1 P-loop containing dynein motor region Torsin PF06309.11 OAJ26627.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Torsin Sigma54_activat PF00158.26 OAJ26627.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ26627.1 - 0.045 13.7 0.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 OAJ26627.1 - 0.075 13.0 0.1 0.24 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 OAJ26627.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 OAJ26627.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GST_C_4 PF14834.6 OAJ26628.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HMMR_C PF15908.5 OAJ26628.1 - 0.1 12.8 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Ribosom_S12_S23 PF00164.25 OAJ26669.1 - 1.4e-33 114.9 0.1 1.9e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S17e PF00833.18 OAJ26672.1 - 3.8e-59 198.0 0.0 4.6e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 OAJ26673.1 - 2e-21 76.2 0.0 3.4e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 FAD_binding_7 PF03441.14 OAJ26710.1 - 7.5e-51 172.5 0.2 1.1e-50 171.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ26710.1 - 1.8e-19 70.4 0.0 4e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase 7TMR-DISMED2 PF07696.11 OAJ26710.1 - 0.02 14.9 0.5 0.15 12.2 0.1 2.3 1 1 1 2 2 2 0 7TMR-DISM extracellular 2 CRAL_TRIO_2 PF13716.6 OAJ26711.1 - 6.5e-30 104.1 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 OAJ26711.1 - 1.3e-23 83.5 0.0 2.3e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Paf1 PF03985.13 OAJ26711.1 - 0.44 9.5 6.8 0.72 8.8 6.8 1.2 1 0 0 1 1 1 0 Paf1 Roughex PF06020.11 OAJ26711.1 - 0.53 9.3 4.0 0.97 8.5 4.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 OAJ26711.1 - 9.1 5.9 7.1 4.2 7.0 2.5 2.4 3 0 0 3 3 3 0 FAM176 family GFO_IDH_MocA PF01408.22 OAJ26713.1 - 1.6e-16 61.2 0.0 2.9e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ26713.1 - 8.5e-11 41.9 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Dcc1 PF09724.9 OAJ26808.1 - 9.5e-67 225.7 0.0 1.7e-66 224.9 0.0 1.4 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 UBA2_C PF16195.5 OAJ26808.1 - 0.18 12.5 3.5 0.43 11.3 0.2 2.6 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Peptidase_S8 PF00082.22 OAJ26810.1 - 1.9e-41 142.3 0.0 4.3e-41 141.1 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ26810.1 - 6.8e-09 36.4 0.0 1.7e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain Lipase_3 PF01764.25 OAJ26812.1 - 1.7e-23 83.1 0.0 2.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ26812.1 - 0.00068 20.3 0.5 0.0013 19.4 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ26812.1 - 0.0023 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 OAJ26812.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold RHH_8 PF17723.1 OAJ26812.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family HMG_box PF00505.19 OAJ26813.1 - 0.14 12.6 6.4 0.27 11.7 6.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box PF00505.19 OAJ26814.1 - 1.4e-08 35.0 3.4 0.00013 22.3 1.7 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ26814.1 - 0.0039 17.7 0.9 0.0091 16.6 0.9 1.6 1 0 0 1 1 1 1 HMG-box domain Drf_GBD PF06371.13 OAJ26860.1 - 2.4e-13 50.1 0.0 4.4e-12 45.9 0.0 2.4 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Connexin PF00029.19 OAJ26860.1 - 0.23 11.2 2.1 0.4 10.4 2.1 1.3 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 OAJ26860.1 - 4.1 6.9 11.2 6.2 6.4 11.2 1.2 1 0 0 1 1 1 0 Spt20 family KCH PF16944.5 OAJ26861.1 - 5.6e-82 275.3 14.5 7.2e-82 274.9 14.5 1.1 1 0 0 1 1 1 1 Fungal potassium channel 2OG-FeII_Oxy_2 PF13532.6 OAJ26862.1 - 1.2e-13 51.7 0.0 7.8e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Serglycin PF04360.12 OAJ26862.1 - 7.8 6.4 6.7 3.7 7.5 4.2 1.7 2 0 0 2 2 2 0 Serglycin zf-CCHC PF00098.23 OAJ26863.1 - 5.9 7.1 10.3 3.5 7.9 5.8 2.5 2 0 0 2 2 2 0 Zinc knuckle ATP-synt_DE_N PF02823.16 OAJ26864.1 - 5.2e-16 58.3 0.0 7.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DBR1 PF05011.13 OAJ26865.1 - 8.6e-24 84.5 0.0 1.5e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 OAJ26865.1 - 2.3e-06 28.3 0.2 4.1e-06 27.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4210 PF13915.6 OAJ26865.1 - 0.026 15.1 0.1 0.074 13.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) HU-HIG PF18291.1 OAJ26902.1 - 0.046 13.8 0.0 1.7 8.8 0.0 2.3 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif PQ-loop PF04193.14 OAJ26903.1 - 3.4e-10 39.5 0.4 3.4e-10 39.5 0.4 1.6 2 0 0 2 2 2 1 PQ loop repeat Form-deh_trans PF09163.11 OAJ26903.1 - 0.0058 16.4 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Formate dehydrogenase N, transmembrane Na_H_Exchanger PF00999.21 OAJ26904.1 - 0.006 15.4 1.2 0.0082 15.0 1.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DOCK_N PF16172.5 OAJ26943.1 - 8.6e-115 383.7 0.0 2.4e-114 382.2 0.0 1.8 2 0 0 2 2 2 1 DOCK N-terminus DHR-2 PF06920.13 OAJ26943.1 - 6.6e-68 229.6 1.5 7.9e-68 229.4 0.0 1.9 3 0 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 OAJ26943.1 - 9.4e-52 175.7 0.0 2.9e-51 174.1 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins CK_II_beta PF01214.18 OAJ26945.1 - 2.6e-80 268.5 0.0 3.2e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FAD_binding_8 PF08022.12 OAJ26946.1 - 1.2e-18 67.1 0.0 2.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 OAJ26946.1 - 7.5e-14 52.1 0.1 4.2e-12 46.4 0.0 3.2 2 2 1 3 3 3 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 OAJ26946.1 - 1.2e-10 41.5 9.4 2.8e-10 40.4 9.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component PAT1 PF09770.9 OAJ26947.1 - 4e-112 376.1 10.7 4.8e-73 246.8 0.0 4.2 2 2 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Transposase_20 PF02371.16 OAJ26947.1 - 0.15 12.4 2.2 0.18 12.2 0.1 2.2 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family ELYS PF13934.6 OAJ26948.1 - 3e-09 37.2 3.4 7.3e-09 35.9 3.4 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly adh_short PF00106.25 OAJ26993.1 - 4.5e-18 65.4 0.0 6.5e-11 42.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ26993.1 - 7.7e-12 45.3 0.0 1.5e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ26993.1 - 4.8e-07 29.5 0.0 6.5e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAJ26993.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 OAJ26993.1 - 0.19 11.1 0.0 6 6.2 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NIR_SIR PF01077.22 OAJ26994.1 - 4.6e-44 149.7 0.0 3.3e-39 134.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 OAJ26994.1 - 3.1e-28 97.4 0.0 3.5e-14 52.4 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 OAJ26994.1 - 1.6e-26 93.3 0.0 3e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 OAJ26994.1 - 3.5e-09 36.7 0.1 3.5e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg T3SSipB PF16535.5 OAJ26994.1 - 0.001 19.5 2.0 0.001 19.5 2.0 2.3 2 0 0 2 2 2 1 Type III cell invasion protein SipB Toprim_N PF08275.11 OAJ26995.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA primase catalytic core, N-terminal domain TetR_C_25 PF17933.1 OAJ26995.1 - 0.19 12.1 0.2 2.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HsbA PF12296.8 OAJ26996.1 - 1.5e-06 28.6 11.7 0.00056 20.3 0.1 2.8 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Apolipoprotein PF01442.18 OAJ26996.1 - 0.018 14.9 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5481 PF17578.2 OAJ26996.1 - 0.11 12.9 0.3 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5481) GST_N PF02798.20 OAJ26997.1 - 1.4e-16 60.6 0.0 3.2e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ26997.1 - 8.4e-16 58.1 0.0 2.2e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ26997.1 - 1.2e-10 41.5 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 OAJ26997.1 - 0.00052 20.7 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 OAJ26997.1 - 0.004 17.5 0.0 0.0084 16.4 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Aldo_ket_red PF00248.21 OAJ27054.1 - 5.9e-13 48.7 0.0 2.1e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Stress-antifung PF01657.17 OAJ27055.1 - 0.03 14.9 6.1 0.035 14.7 6.1 1.1 1 0 0 1 1 1 0 Salt stress response/antifungal Gpi1 PF05024.15 OAJ27058.1 - 7.6e-55 185.9 0.5 1.2e-54 185.3 0.5 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FXMR_C2 PF16098.5 OAJ27058.1 - 8.2 7.0 7.4 8.2 7.0 0.1 2.7 2 1 1 3 3 3 0 Fragile X-related mental retardation protein C-terminal region 2 YjbE PF11106.8 OAJ27063.1 - 0.0018 18.4 3.9 0.0033 17.6 3.9 1.5 1 0 0 1 1 1 1 Exopolysaccharide production protein YjbE U71 PF17474.2 OAJ27063.1 - 0.032 14.1 0.0 4.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Tegument protein UL11 homolog DUF1155 PF06633.11 OAJ27063.1 - 0.16 11.4 0.1 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) TMEM171 PF15471.6 OAJ27064.1 - 0.015 14.3 0.9 0.023 13.7 0.9 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Cutinase PF01083.22 OAJ27065.1 - 3.1e-18 66.3 0.0 3.8e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.7 OAJ27065.1 - 0.0021 18.7 0.3 0.0025 18.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ27065.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Nsp3_PL2pro PF12124.8 OAJ27065.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain YgaB PF14182.6 OAJ27066.1 - 0.2 12.1 1.6 0.37 11.2 1.6 1.6 1 1 0 1 1 1 0 YgaB-like protein DDE_Tnp_4 PF13359.6 OAJ27116.1 - 2.7e-25 88.9 0.0 3.8e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ27116.1 - 1.7e-07 31.1 0.0 4.7e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 OAJ27116.1 - 9.8e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 OAJ27116.1 - 0.00038 20.8 2.0 0.0026 18.1 0.1 2.3 2 0 0 2 2 2 1 Transposase DDE domain Fer4 PF00037.27 OAJ27117.1 - 5.7e-15 54.4 16.4 8.9e-09 34.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 OAJ27117.1 - 2.2e-13 50.5 10.4 3.4e-13 49.9 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAJ27117.1 - 5.6e-11 43.2 8.6 9.1e-06 26.5 0.8 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 OAJ27117.1 - 3.9e-10 39.7 6.8 6.9e-05 22.9 0.6 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 OAJ27117.1 - 6.1e-10 39.1 21.6 1.3e-06 28.4 12.6 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 OAJ27117.1 - 2.5e-09 37.4 3.1 7.2e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 OAJ27117.1 - 4.5e-09 36.3 10.2 7.7e-09 35.6 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 OAJ27117.1 - 1.2e-07 31.5 17.8 0.00021 21.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 OAJ27117.1 - 3.8e-07 29.8 12.5 0.0014 18.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 OAJ27117.1 - 1.6e-06 28.2 10.8 0.00017 21.8 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 OAJ27117.1 - 4.3e-05 24.0 10.9 0.0085 16.6 11.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 OAJ27117.1 - 0.00012 22.6 9.8 0.056 14.0 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 OAJ27117.1 - 0.0025 18.0 4.9 0.4 10.9 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 OAJ27117.1 - 0.015 15.5 9.3 5.7 7.2 8.0 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 OAJ27117.1 - 0.064 14.2 16.3 0.19 12.8 4.1 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 OAJ27117.1 - 0.083 13.7 11.4 1.3 10.0 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 OAJ27117.1 - 0.11 12.6 6.3 0.88 9.7 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 OAJ27117.1 - 0.38 10.8 6.7 0.4 10.7 0.8 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins ACOX PF01756.19 OAJ27120.1 - 1.7e-44 151.5 0.8 4.1e-44 150.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 OAJ27120.1 - 5.4e-22 78.7 0.1 1.2e-21 77.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAJ27120.1 - 4.4e-09 36.4 0.0 7.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ27120.1 - 5.8e-06 26.6 0.3 0.00032 21.0 0.3 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ27120.1 - 0.07 13.8 0.0 0.23 12.2 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Myb_DNA-bind_3 PF12776.7 OAJ27121.1 - 3.1e-17 63.3 0.1 5e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ27121.1 - 5.9e-06 26.6 0.6 0.00012 22.4 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain STT3 PF02516.14 OAJ27166.1 - 6.5e-147 490.4 32.1 3.6e-142 474.7 29.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit RhoGAP PF00620.27 OAJ27167.1 - 3.5e-36 124.3 0.0 7.6e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF664 PF04978.12 OAJ27167.1 - 3 8.3 6.5 5.2 7.5 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF664) tRNA-synt_1g PF09334.11 OAJ27168.1 - 1.7e-150 501.2 0.1 2.1e-150 500.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 OAJ27168.1 - 4.2e-07 28.6 1.4 3.5e-05 22.3 0.0 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 OAJ27168.1 - 2.7e-05 24.2 4.2 2.7e-05 24.2 4.2 2.2 1 1 1 2 2 2 1 WHEP-TRS domain DZR PF12773.7 OAJ27168.1 - 0.13 12.3 3.7 0.31 11.1 3.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAJ27168.1 - 0.52 10.5 2.1 6.6 6.9 0.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 OAJ27168.1 - 0.88 9.4 0.0 0.88 9.4 0.0 2.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 OAJ27168.1 - 4.9 6.7 5.6 30 4.2 1.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Brix PF04427.18 OAJ27169.1 - 1.9e-21 77.0 0.0 2.6e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 OAJ27169.1 - 0.35 10.2 30.9 0.016 14.6 20.8 2.1 2 0 0 2 2 2 0 BUD22 BSP_II PF05432.11 OAJ27169.1 - 3 7.5 17.0 0.21 11.2 8.9 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) EphA2_TM PF14575.6 OAJ27170.1 - 0.13 13.2 0.0 2.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MCM_lid PF17855.1 OAJ27171.1 - 0.047 14.1 0.2 0.13 12.7 0.2 1.7 1 0 0 1 1 1 0 MCM AAA-lid domain DUF1571 PF07608.11 OAJ27172.1 - 0.095 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) CRAL_TRIO PF00650.20 OAJ27243.1 - 0.12 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain TPK_catalytic PF04263.16 OAJ27244.1 - 3.2e-26 91.7 0.0 4.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 OAJ27244.1 - 1.5e-10 40.6 0.0 2.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Ferric_reduct PF01794.19 OAJ27245.1 - 1.2e-23 83.6 11.3 1.2e-23 83.6 11.3 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ27245.1 - 2.2e-17 63.6 0.0 3.2e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ27245.1 - 4.1e-10 39.7 0.0 9.3e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ27245.1 - 0.0064 17.1 0.0 0.063 13.9 0.0 2.2 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain ssDBP PF17878.1 OAJ27246.1 - 0.066 13.5 0.3 0.09 13.0 0.3 1.2 1 0 0 1 1 1 0 Single-stranded DNA-binding protein COS PF18568.1 OAJ27248.1 - 0.056 13.4 0.3 7.6 6.6 0.0 2.2 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain Apolipoprotein PF01442.18 OAJ27250.1 - 0.00035 20.5 9.9 0.00045 20.1 9.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ27250.1 - 0.019 15.0 6.9 0.13 12.3 2.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3461 PF11944.8 OAJ27250.1 - 0.035 14.3 1.5 0.065 13.4 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3461) DUF1640 PF07798.11 OAJ27250.1 - 0.045 13.8 5.7 0.24 11.4 5.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Gp-FAR-1 PF05823.12 OAJ27250.1 - 0.074 13.4 0.3 0.11 12.9 0.3 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Cor1 PF04803.12 OAJ27250.1 - 0.076 13.2 0.9 0.076 13.2 0.9 2.1 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Fzo_mitofusin PF04799.13 OAJ27250.1 - 0.11 12.0 6.3 0.087 12.4 3.9 2.0 1 1 1 2 2 2 0 fzo-like conserved region Bacillus_HBL PF05791.11 OAJ27250.1 - 0.24 11.2 4.6 0.41 10.5 2.2 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3907 PF13047.6 OAJ27250.1 - 0.29 11.1 1.6 14 5.6 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3907) PIF1 PF05970.14 OAJ27251.1 - 2.1e-22 79.8 0.0 2.6e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ27251.1 - 2.3e-22 80.1 0.0 4.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ27251.1 - 9.5e-13 48.3 1.5 1.3e-12 47.8 0.2 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ27251.1 - 6e-08 33.1 0.4 4.6e-07 30.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 OAJ27251.1 - 0.0014 19.1 0.0 0.0062 16.9 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 OAJ27251.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.14 OAJ27251.1 - 0.073 13.1 0.1 0.27 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAJ27251.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_M48_N PF16491.5 OAJ27319.1 - 1.8e-58 197.5 3.2 3.4e-58 196.5 3.2 1.5 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 OAJ27319.1 - 3e-30 105.5 0.1 2.4e-23 82.9 0.0 2.9 2 1 0 2 2 2 2 Peptidase family M48 Peptidase_M56 PF05569.11 OAJ27319.1 - 0.0096 15.1 0.1 0.0096 15.1 0.1 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 Hydrolase_4 PF12146.8 OAJ27320.1 - 2.5e-12 46.6 0.0 4.2e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ27320.1 - 6.2e-12 46.6 0.1 8.3e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ27320.1 - 1.1e-10 41.7 0.2 2.3e-07 30.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ27320.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 OAJ27320.1 - 0.14 11.7 0.0 20 4.6 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 OAJ27320.1 - 0.14 12.2 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Acyl-CoA_dh_1 PF00441.24 OAJ27321.1 - 9.4e-37 126.5 0.1 1.3e-36 126.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ27321.1 - 7.2e-18 64.6 0.1 1.2e-17 63.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 OAJ27321.1 - 3.7e-14 53.3 0.0 8.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 OAJ27321.1 - 5.4e-12 46.1 0.0 8.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Orn_Arg_deC_N PF02784.16 OAJ27323.1 - 3.8e-25 88.7 0.0 5.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 OAJ27323.1 - 0.0024 18.1 0.1 0.0057 16.9 0.1 1.6 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 OAJ27323.1 - 0.11 13.1 0.0 0.99 10.0 0.0 2.4 1 1 0 1 1 1 0 Arginine decarboxylase C-terminal helical extension eIF-3c_N PF05470.12 OAJ27324.1 - 2.4e-181 604.1 4.1 2.4e-181 604.1 4.1 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 OAJ27324.1 - 9e-08 32.6 0.0 3.2e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 PCI domain CABIT PF12736.7 OAJ27324.1 - 0.025 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, DUF3439 PF11921.8 OAJ27324.1 - 2.1 8.3 6.5 0.13 12.2 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CDC45 PF02724.14 OAJ27324.1 - 5 5.3 21.5 9.8 4.3 21.4 1.5 1 1 0 1 1 1 0 CDC45-like protein Aconitase_2_N PF06434.13 OAJ27326.1 - 0.054 13.1 0.0 0.076 12.6 0.0 1.1 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus APH PF01636.23 OAJ27328.1 - 8.5e-20 71.7 0.2 8.5e-20 71.7 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ27328.1 - 0.041 13.5 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family TIM21 PF08294.11 OAJ27329.1 - 9.4e-13 48.3 0.1 1.8e-11 44.1 0.0 2.6 2 1 0 2 2 2 1 TIM21 DUF1744 PF08490.12 OAJ27331.1 - 7.8e-132 439.6 0.0 1.2e-131 439.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 OAJ27331.1 - 5.1e-78 262.6 0.0 8.4e-78 261.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 OAJ27331.1 - 1.3e-12 47.2 0.1 5e-11 42.0 0.2 3.1 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 OAJ27331.1 - 3e-09 36.9 0.1 9.9e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 OAJ27331.1 - 1.6e-05 25.0 0.0 6.4e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily LPD14 PF18827.1 OAJ27331.1 - 0.1 12.8 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 HHH_3 PF12836.7 OAJ27331.1 - 0.17 12.2 0.0 0.69 10.2 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif IDO PF01231.18 OAJ27332.1 - 1.6e-40 139.2 0.0 2.6e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase HSP9_HSP12 PF04119.12 OAJ27333.1 - 1.2e-17 64.0 7.6 1.2e-17 64.0 5.8 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Endosulfine PF04667.17 OAJ27334.1 - 3.3e-23 81.6 0.1 8.3e-23 80.3 0.1 1.7 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DDE_3 PF13358.6 OAJ27335.1 - 1.3e-26 93.1 0.0 2.2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ27335.1 - 6.2e-09 36.3 0.4 3.9e-06 27.4 0.3 2.9 2 0 0 2 2 2 2 Homeodomain-like domain HTH_33 PF13592.6 OAJ27335.1 - 7.4e-06 25.5 0.1 3.1e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 OAJ27335.1 - 0.0031 17.7 0.0 0.008 16.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_ISAZ013 PF07592.11 OAJ27335.1 - 0.037 13.0 0.1 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain HTH_Tnp_Tc3_2 PF01498.18 OAJ27335.1 - 0.056 13.7 0.9 0.25 11.6 0.2 2.3 2 0 0 2 2 2 0 Transposase HTH_23 PF13384.6 OAJ27335.1 - 0.07 13.0 0.2 1.5 8.7 0.0 2.9 2 1 0 2 2 2 0 Homeodomain-like domain HTH_7 PF02796.15 OAJ27335.1 - 0.074 13.1 0.3 2.1 8.5 0.1 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase ERG4_ERG24 PF01222.17 OAJ27336.1 - 1.7e-139 465.3 4.1 2e-139 465.1 4.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 OAJ27336.1 - 3.4e-05 23.5 0.1 7.1e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 OAJ27336.1 - 0.00098 19.5 1.4 0.0026 18.1 0.0 2.5 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 OAJ27336.1 - 0.0037 17.7 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TMEM119 PF15724.5 OAJ27336.1 - 0.21 11.6 1.0 0.33 11.0 1.0 1.2 1 0 0 1 1 1 0 TMEM119 family RNase_II_C_S1 PF18614.1 OAJ27337.1 - 0.0025 17.7 0.2 0.0065 16.4 0.2 1.6 1 0 0 1 1 1 1 RNase II-type exonuclease C-terminal S1 domain DPM2 PF07297.12 OAJ27337.1 - 0.11 12.8 0.5 0.18 12.2 0.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TraG_N PF07916.11 OAJ27339.1 - 2.8 6.7 5.3 2.2 7.0 2.8 1.8 1 1 1 2 2 2 0 TraG-like protein, N-terminal region Band_7 PF01145.25 OAJ27339.1 - 2.8 7.9 25.6 20 5.1 0.0 4.2 2 1 0 2 2 2 0 SPFH domain / Band 7 family FA_hydroxylase PF04116.13 OAJ27340.1 - 4.1e-19 69.2 2.1 4.1e-19 69.2 2.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Retrotran_gag_2 PF14223.6 OAJ27341.1 - 1.9e-18 66.5 0.1 2.9e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 OAJ27341.1 - 8.6e-17 61.6 0.0 1.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ27341.1 - 7.3e-15 55.2 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ27341.1 - 2.9e-08 33.5 0.0 6.9e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ27341.1 - 0.0013 18.5 0.0 0.005 16.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Propeptide_C1 PF08127.13 OAJ27341.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide zf-CCHC PF00098.23 OAJ27341.1 - 0.066 13.3 10.0 0.069 13.3 1.8 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ27341.1 - 2.5 7.9 3.6 23 4.8 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 OAJ27342.1 - 4e-17 62.3 5.2 6.2e-05 23.7 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat PD40 PF07676.12 OAJ27342.1 - 0.012 15.5 0.9 0.044 13.7 0.1 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 OAJ27342.1 - 0.019 15.3 0.0 22 5.4 0.0 4.3 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Cpn60_TCP1 PF00118.24 OAJ27343.1 - 6e-157 523.2 0.8 7.2e-157 522.9 0.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIB PF00382.19 OAJ27344.1 - 1.2e-26 92.5 0.0 5.1e-18 64.9 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 OAJ27344.1 - 1.4e-26 92.7 3.5 1.4e-26 92.7 3.5 4.2 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 OAJ27344.1 - 8.8e-08 31.5 1.2 1.7e-07 30.6 1.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 OAJ27344.1 - 5.9e-05 22.8 0.0 0.48 10.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain CDC27 PF09507.10 OAJ27344.1 - 0.00097 18.6 7.4 0.00097 18.6 7.4 3.8 2 1 1 3 3 3 1 DNA polymerase subunit Cdc27 Ribosomal_S27e PF01667.17 OAJ27344.1 - 0.09 12.5 0.9 0.16 11.7 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DNA_RNApol_7kD PF03604.13 OAJ27344.1 - 2.5 7.8 4.0 5.4 6.8 4.0 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Las1 PF04031.13 OAJ27345.1 - 1.3e-42 145.5 0.2 1.6e-42 145.2 0.2 1.1 1 0 0 1 1 1 1 Las1-like Methyltransf_31 PF13847.6 OAJ27346.1 - 9.8e-15 54.7 0.0 1.9e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ27346.1 - 2.3e-06 28.2 0.0 9e-06 26.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ27346.1 - 1.1e-05 26.1 0.0 2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 OAJ27346.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ27346.1 - 0.00031 20.6 0.0 0.00071 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ27346.1 - 0.00091 19.8 0.0 0.016 15.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain MetW PF07021.12 OAJ27346.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Spo12 PF05032.12 OAJ27347.1 - 9.5e-14 51.0 5.0 2.1e-13 49.9 5.0 1.6 1 0 0 1 1 1 1 Spo12 family SnoaL_2 PF12680.7 OAJ27347.1 - 0.00087 19.9 0.1 0.0014 19.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain ubiquitin PF00240.23 OAJ27348.1 - 8.6e-25 86.3 0.1 9.5e-25 86.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ27348.1 - 1.2e-13 50.7 0.0 1.3e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ27348.1 - 0.0004 20.8 0.0 0.00048 20.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ27348.1 - 0.0038 17.1 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HATPase_c PF02518.26 OAJ27348.1 - 0.016 15.7 0.0 0.016 15.7 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Smg4_UPF3 PF03467.15 OAJ27349.1 - 1.6e-52 178.1 0.1 1.6e-52 178.1 0.1 3.4 4 0 0 4 4 4 1 Smg-4/UPF3 family LIAS_N PF16881.5 OAJ27349.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.7 3 0 0 3 3 3 0 N-terminal domain of lipoyl synthase of Radical_SAM family CAP59_mtransfer PF11735.8 OAJ27349.1 - 0.78 9.4 3.3 3.1 7.4 1.9 2.2 2 0 0 2 2 2 0 Cryptococcal mannosyltransferase 1 2-Hacid_dh_C PF02826.19 OAJ27350.1 - 7.4e-40 136.2 0.0 1.7e-28 99.2 0.1 2.2 1 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ27350.1 - 7.3e-24 83.9 0.0 9.9e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Mito_carr PF00153.27 OAJ27351.1 - 1e-46 156.8 6.1 5.5e-16 58.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4773 PF15998.5 OAJ27352.1 - 0.63 10.6 4.5 0.86 10.2 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4773) zf-CCHC PF00098.23 OAJ27353.1 - 1.4e-10 40.7 38.3 4.9e-07 29.5 1.2 5.3 5 0 0 5 5 5 4 Zinc knuckle Zn_Tnp_IS91 PF14319.6 OAJ27353.1 - 5.2 7.2 15.0 3.2 7.8 4.1 2.8 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-CCHC_4 PF14392.6 OAJ27353.1 - 8.7 6.2 19.3 3.8 7.3 0.7 4.4 4 0 0 4 4 4 0 Zinc knuckle Hamartin PF04388.12 OAJ27354.1 - 0.011 14.5 7.9 0.014 14.1 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 OAJ27354.1 - 0.061 13.3 14.1 0.11 12.4 14.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 OAJ27354.1 - 2.8 7.5 8.0 5 6.7 8.0 1.4 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 OAJ27354.1 - 3.5 6.2 6.6 5.2 5.6 6.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PH PF00169.29 OAJ27355.1 - 8.3e-09 35.9 0.1 0.0023 18.4 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 OAJ27355.1 - 3.9e-08 33.7 0.6 0.0016 18.8 0.1 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 OAJ27355.1 - 0.02 15.3 0.6 1.5 9.3 0.2 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain TPR_10 PF13374.6 OAJ27356.1 - 0.0053 16.6 0.3 4.3 7.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Glyco_transf_54 PF04666.13 OAJ27357.1 - 2.4e-05 23.4 0.0 0.037 12.9 0.0 3.0 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region NDC10_II PF16787.5 OAJ27358.1 - 2.3e-45 155.1 0.0 3.7e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ27358.1 - 0.0037 17.5 0.1 0.0084 16.4 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_29 PF13551.6 OAJ27358.1 - 0.031 14.3 0.0 0.16 12.0 0.0 2.3 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 OAJ27358.1 - 0.035 13.9 0.2 6 6.8 0.0 3.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.20 OAJ27358.1 - 0.05 13.9 0.6 0.37 11.1 0.0 2.7 3 0 0 3 3 3 0 Transposase PXA PF02194.15 OAJ27358.1 - 0.08 12.9 0.8 0.23 11.4 0.8 1.7 1 0 0 1 1 1 0 PXA domain Sulfate_transp PF00916.20 OAJ27359.1 - 0.0007 18.5 0.4 0.00094 18.0 0.4 1.1 1 0 0 1 1 1 1 Sulfate permease family Zn_clus PF00172.18 OAJ27360.1 - 2e-06 27.8 4.8 1.2e-05 25.3 4.8 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ27362.1 - 6e-06 25.5 0.0 1.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ27362.1 - 0.0027 17.8 5.9 0.27 11.4 0.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CcdA PF07362.12 OAJ27362.1 - 0.24 11.9 0.5 0.6 10.6 0.5 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DSPc PF00782.20 OAJ27363.1 - 2.8e-06 27.2 0.0 7.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ27363.1 - 6.9e-05 22.5 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.12 OAJ27363.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 OAJ27363.1 - 0.073 13.2 0.0 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate PPR_2 PF13041.6 OAJ27364.1 - 5.5e-33 112.9 0.0 3.4e-10 39.9 0.0 8.6 8 1 2 10 10 10 6 PPR repeat family PPR_3 PF13812.6 OAJ27364.1 - 1.6e-27 95.4 0.0 9.6e-13 48.0 0.0 5.9 4 2 1 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.20 OAJ27364.1 - 1.1e-25 88.0 5.0 0.00018 21.5 0.0 11.0 11 2 0 11 11 11 5 PPR repeat PPR_1 PF12854.7 OAJ27364.1 - 5.7e-18 64.3 0.6 7.2e-07 28.8 0.0 6.5 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 OAJ27364.1 - 1.3e-13 50.9 0.0 1.4e-11 44.2 0.0 3.4 3 1 1 4 4 4 1 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 OAJ27364.1 - 0.012 15.6 0.0 33 4.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyclin_N PF00134.23 OAJ27365.1 - 1.4e-39 134.8 0.6 6.2e-38 129.4 0.6 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 OAJ27365.1 - 2.5e-27 95.3 0.0 4.9e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain CBF PF03914.17 OAJ27366.1 - 2.1e-39 135.3 0.1 2.1e-39 135.3 0.1 2.7 2 1 0 2 2 2 1 CBF/Mak21 family DUF2722 PF10846.8 OAJ27366.1 - 0.0041 16.1 7.2 0.0041 16.1 7.2 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) Cnd1 PF12717.7 OAJ27366.1 - 0.024 14.7 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ27366.1 - 0.048 12.2 0.0 0.44 9.1 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Suf PF05843.14 OAJ27366.1 - 4.3 7.2 11.8 0.31 11.0 3.1 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) zf-C2H2_aberr PF17017.5 OAJ27367.1 - 9.4e-05 22.6 5.5 0.11 12.7 0.3 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 OAJ27367.1 - 0.0082 16.6 7.9 0.5 10.9 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ27367.1 - 0.68 10.9 12.9 6.4 7.9 0.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ27367.1 - 0.95 10.0 6.4 9.4 6.9 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain DUF1631 PF07793.11 OAJ27367.1 - 6.5 5.0 8.9 11 4.2 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) FOXP-CC PF16159.5 OAJ27367.1 - 6.7 7.4 5.9 15 6.3 0.9 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain 4HBT_3 PF13622.6 OAJ27368.1 - 9.3e-32 111.2 0.2 1.4e-31 110.7 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ27368.1 - 0.00027 20.8 0.0 0.00058 19.7 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA thioesterase DPBB_1 PF03330.18 OAJ27369.1 - 1e-05 25.7 1.2 1.3e-05 25.3 0.0 1.9 2 1 0 2 2 2 1 Lytic transglycolase eIF3_subunit PF08597.10 OAJ27369.1 - 0.0011 18.9 4.4 0.0017 18.3 4.4 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Barwin PF00967.17 OAJ27369.1 - 0.017 14.9 0.9 0.038 13.8 0.9 1.6 1 0 0 1 1 1 0 Barwin family TonB_N PF16031.5 OAJ27369.1 - 0.89 10.1 25.1 2.1 8.9 25.1 1.6 1 0 0 1 1 1 0 TonB polyproline region ATG16 PF08614.11 OAJ27369.1 - 1.6 8.9 6.2 2.2 8.5 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Apt1 PF10351.9 OAJ27369.1 - 3.9 6.2 10.5 5.1 5.8 10.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Trypan_PARP PF05887.11 OAJ27369.1 - 5.3 7.0 16.4 4.2 7.4 14.5 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L14 PF00238.19 OAJ27370.1 - 4.8e-34 117.1 0.1 1.1e-33 115.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Kri1_C PF12936.7 OAJ27370.1 - 2e-22 79.1 0.1 2e-22 79.1 0.1 4.0 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 OAJ27370.1 - 1.4e-21 76.9 10.3 1.4e-21 76.9 10.3 5.9 5 2 1 6 6 6 1 KRI1-like family Toxin_29 PF08116.11 OAJ27371.1 - 0.31 11.1 0.0 0.31 11.1 0.0 5.5 5 1 1 6 6 6 0 PhTx neurotoxin family UPF0506 PF11703.8 OAJ27371.1 - 2.3 8.6 42.8 0.32 11.4 7.1 4.7 2 2 2 4 4 4 0 UPF0506 zf-Sec23_Sec24 PF04810.15 OAJ27372.1 - 0.13 12.4 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Mannosidase_ig PF17786.1 OAJ27373.1 - 3.3e-09 37.2 0.2 9.8e-09 35.7 0.2 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 OAJ27373.1 - 4.5e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Tubulin_3 PF14881.6 OAJ27374.1 - 7.7e-29 100.7 14.0 3.6e-19 69.1 11.0 4.3 2 1 0 2 2 2 2 Tubulin domain Misat_Tub_SegII PF10644.9 OAJ27374.1 - 1.8e-26 92.8 0.0 6.8e-26 90.9 0.0 2.1 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain MT-A70 PF05063.14 OAJ27375.1 - 1.3e-49 168.4 0.0 9.5e-34 116.8 0.0 2.2 2 0 0 2 2 2 2 MT-A70 Retrotrans_gag PF03732.17 OAJ27376.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein Shugoshin_N PF07558.11 OAJ27376.1 - 0.12 12.3 2.7 5.2 7.0 0.0 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF2205 PF10224.9 OAJ27376.1 - 0.12 12.3 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Short coiled-coil protein RT_RNaseH_2 PF17919.1 OAJ27377.1 - 2.2e-23 82.2 0.0 3.8e-15 55.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ27377.1 - 1.4e-22 80.3 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 OAJ27377.1 - 3.3e-16 59.5 0.0 1.1e-10 41.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ27377.1 - 2.1e-14 53.4 0.0 3.9e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ27377.1 - 5.3e-11 42.8 0.0 2.8e-10 40.4 0.0 2.3 3 0 0 3 3 3 1 Integrase core domain dUTPase PF00692.19 OAJ27377.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 dUTPase KDZ PF18758.1 OAJ27378.1 - 8.1e-41 140.1 0.0 2e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ27378.1 - 0.00068 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ27378.1 - 0.0048 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Adenyl_cycl_N PF12633.7 OAJ27378.1 - 0.076 12.9 2.5 2.1 8.2 0.5 2.4 2 0 0 2 2 2 0 Adenylate cyclase NT domain MFS_1 PF07690.16 OAJ27381.1 - 2.4e-17 62.9 46.0 2.4e-17 62.9 46.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ27381.1 - 0.0014 17.0 2.6 0.0087 14.4 0.0 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CMAS PF02353.20 OAJ27382.1 - 1e-33 116.8 0.4 4.5e-33 114.7 0.4 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ27382.1 - 5e-12 46.4 0.0 1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ27382.1 - 8e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ27382.1 - 3.5e-09 36.6 0.0 1e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ27382.1 - 5.6e-06 26.3 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ27382.1 - 1.2e-05 25.9 0.0 2.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ27382.1 - 2.8e-05 23.7 0.0 6.1e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 OAJ27382.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 OAJ27382.1 - 0.0046 16.4 0.1 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 OAJ27382.1 - 0.0047 16.6 0.0 0.0079 15.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F GidB PF02527.15 OAJ27382.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MetW PF07021.12 OAJ27382.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Chitin_synth_2 PF03142.15 OAJ27383.1 - 1.6e-281 934.5 0.1 2e-281 934.2 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 OAJ27383.1 - 6.5e-13 49.1 0.1 2.1e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ27383.1 - 6.7e-11 42.5 1.8 1.9e-10 41.0 1.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ27383.1 - 0.00075 19.0 0.1 0.013 15.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ27383.1 - 0.017 15.0 0.0 0.074 12.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pkinase PF00069.25 OAJ27387.1 - 6.8e-63 212.5 0.0 9.4e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27387.1 - 9.7e-28 97.1 0.0 4.9e-27 94.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ27387.1 - 1.8e-05 25.3 2.5 5.2e-05 23.9 0.7 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 OAJ27387.1 - 0.0023 16.8 0.0 0.0075 15.1 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 OAJ27387.1 - 0.0062 16.2 0.0 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 OAJ27387.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ27387.1 - 0.11 12.4 3.9 2.3 8.1 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family PAS_9 PF13426.7 OAJ27388.1 - 4.5e-24 84.7 0.0 7.7e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 OAJ27388.1 - 6.6e-16 58.3 0.0 4e-09 36.5 0.0 3.3 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.12 OAJ27388.1 - 1.3e-12 47.9 0.0 1.2e-07 32.0 0.0 3.8 3 1 0 3 3 3 2 PAS fold PAS_4 PF08448.10 OAJ27388.1 - 1.5e-08 34.8 0.0 0.0018 18.5 0.0 4.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 OAJ27388.1 - 1.9e-05 24.6 0.0 0.0091 16.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 OAJ27388.1 - 0.0097 16.0 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 1 PAS domain MID_MedPIWI PF18296.1 OAJ27389.1 - 0.13 12.1 5.1 0.2 11.4 5.1 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Kei1 PF08552.11 OAJ27389.1 - 0.22 11.4 2.6 0.32 10.9 2.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Macoilin PF09726.9 OAJ27389.1 - 0.52 8.8 6.7 0.67 8.4 6.7 1.1 1 0 0 1 1 1 0 Macoilin family FSA_C PF10479.9 OAJ27389.1 - 0.8 7.8 11.0 1.6 6.8 11.0 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF483 PF04467.12 OAJ27390.1 - 0.0054 16.7 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF483) NDC10_II PF16787.5 OAJ27393.1 - 4.8e-28 98.1 0.0 6.6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ27393.1 - 5.8e-18 65.0 1.7 9.8e-18 64.3 1.7 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NPV_P10 PF05531.12 OAJ27393.1 - 0.26 11.8 2.1 0.68 10.4 2.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EF-hand_8 PF13833.6 OAJ27394.1 - 0.00081 19.2 0.1 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 OAJ27394.1 - 0.009 16.5 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 OAJ27394.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 OAJ27394.1 - 0.03 13.9 0.1 0.064 12.8 0.0 1.6 2 0 0 2 2 2 0 EF hand Sugar_tr PF00083.24 OAJ27397.1 - 0.0033 16.3 5.1 0.0042 16.0 5.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1115 PF06544.12 OAJ27398.1 - 0.0015 18.7 0.0 0.03 14.4 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) Not3 PF04065.15 OAJ27398.1 - 0.16 11.4 0.3 0.26 10.7 0.3 1.3 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component NicO PF03824.16 OAJ27399.1 - 1.5e-31 109.8 9.2 4.2e-14 52.6 0.0 5.0 4 1 1 5 5 5 3 High-affinity nickel-transport protein TRP PF06011.12 OAJ27399.1 - 0.0018 17.1 0.1 0.0028 16.5 0.1 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel PDGLE PF13190.6 OAJ27399.1 - 0.21 11.5 1.9 0.37 10.7 0.0 2.4 2 1 0 2 2 2 0 PDGLE domain DsbD_2 PF13386.6 OAJ27399.1 - 0.47 10.3 7.8 13 5.7 0.0 4.4 4 1 0 4 4 4 0 Cytochrome C biogenesis protein transmembrane region DUF3309 PF11752.8 OAJ27399.1 - 0.48 10.5 11.9 0.63 10.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF3818 PF12825.7 OAJ27400.1 - 2.7e-45 154.9 0.0 3.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ27400.1 - 6.8e-26 90.8 0.0 1.2e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 PX-associated APG6_N PF17675.1 OAJ27402.1 - 1.8 9.1 15.2 6.9 7.2 15.2 2.0 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 OAJ27402.1 - 2.3 6.0 7.2 3.5 5.4 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF572 PF04502.13 OAJ27402.1 - 3.9 7.0 18.0 0.12 11.9 11.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) LCD1 PF09798.9 OAJ27402.1 - 8.1 4.8 10.6 4.6 5.6 0.0 2.3 2 0 0 2 2 2 0 DNA damage checkpoint protein DUF1771 PF08590.10 OAJ27406.1 - 2.8e-18 66.0 4.0 4.1e-18 65.5 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ27406.1 - 7.5e-13 48.7 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Smr domain DUF3450 PF11932.8 OAJ27407.1 - 0.0053 16.1 0.3 0.23 10.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) DUF4140 PF13600.6 OAJ27407.1 - 0.0095 16.4 1.3 0.48 10.9 1.3 2.1 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 OAJ27407.1 - 0.011 16.2 0.2 1.7 9.1 0.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM60A PF15396.6 OAJ27408.1 - 6.5 6.7 9.6 1.8 8.5 5.7 1.9 2 0 0 2 2 2 0 Protein Family FAM60A Ssl1 PF04056.14 OAJ27409.1 - 3.3e-69 232.5 0.0 7.1e-69 231.5 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 OAJ27409.1 - 3.2e-15 56.1 4.7 3.2e-15 56.1 4.7 3.3 2 1 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.6 OAJ27409.1 - 5.7e-12 46.2 0.0 1.4e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 OAJ27409.1 - 0.00029 21.5 4.6 0.0078 16.9 1.9 3.0 2 1 0 2 2 2 1 zinc-ribbon family IBR PF01485.21 OAJ27409.1 - 0.0024 18.0 0.7 0.0024 18.0 0.7 3.0 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain VWA PF00092.28 OAJ27409.1 - 0.026 14.8 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain zf-C4H2 PF10146.9 OAJ27409.1 - 0.072 13.4 3.4 17 5.6 0.0 2.6 2 1 0 2 2 2 0 Zinc finger-containing protein Tfb4 PF03850.14 OAJ27409.1 - 0.57 9.6 6.7 4 6.9 6.2 2.4 2 1 1 3 3 3 0 Transcription factor Tfb4 DZR PF12773.7 OAJ27409.1 - 1.8 8.6 23.6 1.1 9.3 8.1 3.2 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 OAJ27409.1 - 2.8 8.0 11.2 40 4.3 2.1 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Dynein_light PF01221.18 OAJ27410.1 - 6.7e-35 119.3 0.1 7.9e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4726 PF15855.5 OAJ27410.1 - 0.0029 17.8 0.6 0.0041 17.3 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4726) Pkinase PF00069.25 OAJ27411.1 - 4.4e-72 242.6 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27411.1 - 1.1e-45 155.9 0.0 1.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 OAJ27411.1 - 1.4e-22 79.8 0.1 3e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 OAJ27411.1 - 6.6e-06 25.1 0.0 9.9e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ27411.1 - 0.00025 20.4 0.0 0.0004 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.12 OAJ27411.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.23 OAJ27411.1 - 0.033 14.1 0.6 0.73 9.7 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ27411.1 - 0.17 11.2 1.7 1.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ27411.1 - 0.36 9.7 1.0 0.93 8.4 1.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain P5CR_dimer PF14748.6 OAJ27412.1 - 7e-38 129.0 3.4 1.9e-37 127.6 3.4 1.8 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 OAJ27412.1 - 7.2e-14 52.2 0.0 3.8e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent TrmK PF04816.12 OAJ27412.1 - 0.08 12.5 0.0 2.4 7.6 0.1 2.2 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Inhibitor_I66 PF16850.5 OAJ27413.1 - 0.001 19.0 0.0 0.0068 16.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I66 SoxE PF06525.11 OAJ27413.1 - 0.11 12.0 0.2 1.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Sulfocyanin (SoxE) domain Inhibitor_I66 PF16850.5 OAJ27414.1 - 0.009 15.9 0.1 0.014 15.3 0.1 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I66 FAM176 PF14851.6 OAJ27415.1 - 2.9 7.5 7.5 11 5.6 0.8 3.1 3 0 0 3 3 3 0 FAM176 family rve PF00665.26 OAJ27416.1 - 8.6e-10 38.9 0.0 6.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ27416.1 - 4.4e-07 29.7 0.0 3e-06 27.0 0.0 2.4 2 1 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ27416.1 - 0.00081 19.1 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Transcript_VP30 PF11507.8 OAJ27416.1 - 0.037 14.1 0.5 0.079 13.0 0.1 1.7 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 RVT_2 PF07727.14 OAJ27417.1 - 7.8e-68 228.7 0.0 1.2e-67 228.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tannase PF07519.11 OAJ27418.1 - 6.7e-07 28.6 0.0 7.7e-07 28.4 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.11 OAJ27419.1 - 5.5e-65 220.1 0.2 2.1e-64 218.2 0.2 1.8 1 1 0 1 1 1 1 Tannase and feruloyl esterase SelP_N PF04592.14 OAJ27419.1 - 4 6.8 15.5 8.6 5.7 15.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RRM_1 PF00076.22 OAJ27420.1 - 1.1e-26 92.4 0.9 7e-07 29.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAJ27420.1 - 0.00043 20.1 0.0 2 8.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 OAJ27420.1 - 0.0012 18.6 0.0 11 5.9 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_3 PF08777.11 OAJ27420.1 - 0.031 14.3 0.0 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 RNA binding motif Mob1_phocein PF03637.17 OAJ27421.1 - 5.5e-77 257.5 0.1 6.5e-77 257.3 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Pyridoxal_deC PF00282.19 OAJ27422.1 - 8.1e-72 242.0 0.0 1e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 OAJ27422.1 - 6.1e-05 22.4 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 OAJ27422.1 - 6.4e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 OAJ27422.1 - 0.0045 15.8 0.0 0.0071 15.1 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Rad4 PF03835.15 OAJ27423.1 - 1.7e-26 92.7 0.0 1.7e-26 92.7 0.0 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 OAJ27423.1 - 2.5e-24 85.5 0.0 4.5e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 OAJ27423.1 - 8.9e-18 63.9 0.0 1.6e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 OAJ27423.1 - 1.3e-07 32.0 1.0 1.3e-06 28.8 0.0 3.1 3 0 0 3 3 3 1 Transglutaminase-like superfamily BHD_2 PF10404.9 OAJ27423.1 - 1e-05 26.3 0.3 1e-05 26.3 0.3 4.0 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Mito_carr PF00153.27 OAJ27424.1 - 1.9e-41 139.9 8.5 8.5e-16 57.7 0.6 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EBP PF05241.12 OAJ27426.1 - 8.1e-61 204.6 8.6 9.5e-61 204.3 8.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein NAD_binding_8 PF13450.6 OAJ27426.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF996 PF06195.13 OAJ27426.1 - 0.057 13.7 0.8 0.086 13.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF996) HR_lesion PF05514.11 OAJ27426.1 - 0.27 11.4 6.1 1.3 9.2 0.1 2.5 3 0 0 3 3 3 0 HR-like lesion-inducing Glyco_transf_20 PF00982.21 OAJ27427.1 - 3.4e-137 458.0 0.0 4.2e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 OAJ27427.1 - 0.00074 20.0 0.1 0.0014 19.1 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 OAJ27427.1 - 0.0071 15.9 0.1 0.64 9.5 0.0 2.5 2 1 0 2 2 2 2 Glycosyl transferases group 1 Sedlin_N PF04628.13 OAJ27428.1 - 4.4e-33 114.2 0.0 2.4e-29 102.1 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 OAJ27428.1 - 3.6e-05 23.7 0.0 4.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sporozoite_P67 PF05642.11 OAJ27428.1 - 0.68 8.0 6.1 0.79 7.7 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF508 PF04370.12 OAJ27428.1 - 4.5 7.0 7.1 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF508) FA_desaturase PF00487.24 OAJ27429.1 - 1 9.2 8.2 0.15 11.8 0.2 3.0 3 1 0 3 3 3 0 Fatty acid desaturase RNA_pol_Rpb1_5 PF04998.17 OAJ27430.1 - 8.7e-101 336.8 0.1 1.1e-100 336.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 OAJ27430.1 - 4.4e-59 199.5 0.1 7e-59 198.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.20 OAJ27430.1 - 8.3e-53 179.0 0.0 1.6e-52 178.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ27430.1 - 3.1e-45 153.9 0.0 6.6e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 OAJ27430.1 - 1e-43 148.6 0.4 1.9e-43 147.7 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 OAJ27430.1 - 1.7e-36 124.5 0.1 3.8e-36 123.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 OAJ27430.1 - 5.2e-26 89.6 234.6 0.0039 17.5 10.0 16.1 11 3 5 18 18 18 16 RNA polymerase Rpb1 C-terminal repeat Evr1_Alr PF04777.13 OAJ27431.1 - 2.2e-27 95.4 0.1 3.2e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF4585 PF15232.6 OAJ27431.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) Phage_integrase PF00589.22 OAJ27432.1 - 0.0048 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Gemin6 PF06372.12 OAJ27432.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Gemin6 protein DNA_pol_viral_C PF00336.18 OAJ27433.1 - 0.1 12.0 1.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RHINO PF15319.6 OAJ27433.1 - 0.18 11.8 2.0 0.35 10.9 2.0 1.5 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein IF-2B PF01008.17 OAJ27434.1 - 7.1e-61 205.9 0.0 9.8e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family FTZ PF03867.14 OAJ27434.1 - 0.0099 15.4 1.6 0.018 14.6 1.6 1.3 1 0 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region Pex14_N PF04695.13 OAJ27434.1 - 3.9 8.1 8.5 1.5 9.5 1.2 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sugar_tr PF00083.24 OAJ27435.1 - 1.4e-85 287.9 20.4 1.6e-85 287.7 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ27435.1 - 6e-28 97.8 22.8 6e-28 97.8 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ27435.1 - 0.00028 19.4 0.5 0.00056 18.5 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAGLU PF05089.12 OAJ27436.1 - 0.042 12.8 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Seryl_tRNA_N PF02403.22 OAJ27436.1 - 3.2 8.0 5.8 1.9 8.8 0.1 2.8 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DDE_3 PF13358.6 OAJ27437.1 - 3.2e-31 108.0 0.0 5.1e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ27437.1 - 1.6e-06 28.6 0.0 4.2e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ27437.1 - 3.6e-05 23.3 0.0 0.00011 21.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 OAJ27437.1 - 0.00046 20.3 0.1 0.16 12.1 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 OAJ27437.1 - 0.0012 19.1 0.0 0.0092 16.2 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.6 OAJ27437.1 - 0.0059 16.4 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain Myotub-related PF06602.14 OAJ27438.1 - 1.4e-141 471.5 0.0 3.2e-141 470.3 0.0 1.5 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain adh_short PF00106.25 OAJ27440.1 - 1.4e-15 57.3 0.3 5.4e-14 52.1 0.8 2.6 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ27440.1 - 3e-07 30.3 1.2 0.02 14.5 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ27440.1 - 0.00019 21.4 3.2 0.0015 18.4 0.5 2.2 2 0 0 2 2 2 1 KR domain RNA_polI_A34 PF08208.11 OAJ27441.1 - 1.9e-12 47.7 21.8 1.9e-12 47.7 21.8 2.3 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TFIIA PF03153.13 OAJ27441.1 - 0.0029 17.7 14.8 0.0043 17.1 14.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 OAJ27441.1 - 0.025 14.0 28.6 0.032 13.6 28.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SID-1_RNA_chan PF13965.6 OAJ27441.1 - 1.5 7.1 2.3 1.5 7.2 2.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC_membrane PF00664.23 OAJ27442.1 - 3.7e-51 174.4 0.8 4.8e-51 174.0 0.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ27442.1 - 1.6e-31 109.6 0.0 5e-31 108.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 OAJ27442.1 - 0.0016 18.8 0.3 0.0081 16.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 OAJ27442.1 - 0.0016 17.9 0.5 0.052 13.0 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 OAJ27442.1 - 0.006 17.0 0.0 0.09 13.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ27442.1 - 0.016 15.5 0.0 0.11 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 OAJ27442.1 - 0.023 13.5 0.5 0.036 12.9 0.0 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAJ27442.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 OAJ27442.1 - 0.038 14.0 0.0 0.83 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 OAJ27442.1 - 0.046 13.5 0.2 5.2 6.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M28 PF04389.17 OAJ27443.1 - 8.3e-33 113.8 0.0 2.8e-32 112.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Lectin_N PF03954.14 OAJ27443.1 - 0.23 11.2 0.2 0.39 10.5 0.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain CCER1 PF15482.6 OAJ27444.1 - 0.00055 19.9 1.0 0.00055 19.9 1.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 TFIIA PF03153.13 OAJ27444.1 - 0.22 11.5 17.1 0.27 11.2 17.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 OAJ27444.1 - 5.6 7.6 19.7 7.9 7.1 19.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydrolase_6 PF13344.6 OAJ27445.1 - 1.6e-28 98.8 0.0 3e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ27445.1 - 3.1e-17 62.4 0.1 5.8e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAJ27445.1 - 2.9e-08 34.0 0.3 7.8e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ27445.1 - 7.3e-08 32.9 0.1 1.3e-06 28.9 0.1 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 OAJ27445.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.10 OAJ27445.1 - 0.025 14.2 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pet100 PF09803.9 OAJ27446.1 - 7e-24 84.1 0.0 1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Pet100 SR-25 PF10500.9 OAJ27446.1 - 0.11 12.1 7.2 0.13 11.9 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLN3 PF02487.17 OAJ27447.1 - 5.5e-114 381.3 0.0 6.6e-114 381.0 0.0 1.1 1 0 0 1 1 1 1 CLN3 protein Nop14 PF04147.12 OAJ27447.1 - 0.092 10.9 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ27447.1 - 6.6 4.7 6.5 11 4.0 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.19 OAJ27447.1 - 7.2 7.3 11.9 0.49 11.0 6.5 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fcf1 PF04900.12 OAJ27448.1 - 1.8e-36 124.5 1.4 2.5e-36 124.0 1.4 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 OAJ27448.1 - 4.3e-11 43.1 0.0 5.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 PIN like domain UreD PF01774.17 OAJ27449.1 - 4.9e-59 199.8 0.4 7.2e-59 199.3 0.4 1.2 1 0 0 1 1 1 1 UreD urease accessory protein Tannase PF07519.11 OAJ27450.1 - 3.7e-72 243.7 0.0 5.8e-64 216.7 0.0 2.7 2 1 0 2 2 2 2 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 OAJ27450.1 - 0.14 11.6 0.0 0.5 9.8 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family GATA PF00320.27 OAJ27451.1 - 6.6e-14 51.2 6.5 1.8e-13 49.9 6.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 OAJ27451.1 - 0.0014 18.9 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold FAM76 PF16046.5 OAJ27451.1 - 0.14 11.5 0.3 0.29 10.4 0.3 1.4 1 0 0 1 1 1 0 FAM76 protein LRR_8 PF13855.6 OAJ27452.1 - 3.8e-16 58.6 20.1 1.7e-09 37.3 11.1 4.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAJ27452.1 - 3.5e-11 43.1 22.3 1.8e-05 25.0 4.0 5.4 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) Torus PF16131.5 OAJ27452.1 - 2.4e-08 34.6 5.3 5.5e-05 23.8 0.6 2.8 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 OAJ27452.1 - 5.8e-07 29.3 7.0 0.00088 19.1 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 OAJ27452.1 - 1.6e-06 27.7 8.0 0.0001 22.0 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ27452.1 - 9.8e-05 22.3 16.9 0.01 15.8 3.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ27452.1 - 0.00015 21.9 0.5 0.0003 21.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger containing family LRR_1 PF00560.33 OAJ27452.1 - 0.0016 18.7 11.9 55 4.9 0.0 7.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 OAJ27452.1 - 0.023 14.7 19.8 14 6.0 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat FMO-like PF00743.19 OAJ27453.1 - 4e-21 75.0 0.0 1.1e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ27453.1 - 2.7e-12 46.6 1.0 1.1e-08 34.7 1.2 2.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ27453.1 - 5.1e-12 45.7 0.2 1.6e-09 37.5 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ27453.1 - 1.5e-10 40.7 0.8 5.6e-08 32.3 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ27453.1 - 2.5e-08 34.0 0.9 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 OAJ27453.1 - 1.3e-06 27.9 1.2 0.015 14.6 0.1 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 OAJ27453.1 - 1.9e-05 25.1 2.4 0.045 14.3 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ27453.1 - 2.5e-05 24.1 8.8 0.00012 21.8 1.4 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ27453.1 - 6.1e-05 21.9 0.2 0.049 12.3 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 OAJ27453.1 - 0.00019 21.4 5.0 0.0064 16.5 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 OAJ27453.1 - 0.0013 19.2 0.0 0.41 11.1 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAJ27453.1 - 0.0015 18.6 0.1 2.1 8.4 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 OAJ27453.1 - 0.0022 17.9 0.3 0.004 17.1 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 OAJ27453.1 - 0.0026 17.0 2.7 0.12 11.6 0.4 2.5 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 OAJ27453.1 - 0.019 14.3 0.2 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 OAJ27453.1 - 0.051 12.9 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.22 OAJ27453.1 - 0.055 12.6 2.5 3.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ27453.1 - 0.082 12.1 1.4 0.83 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 OAJ27453.1 - 0.11 11.5 7.2 0.067 12.3 0.4 2.4 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 OAJ27453.1 - 0.14 11.5 0.4 15 4.9 0.1 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 OAJ27453.1 - 0.24 11.0 0.5 0.53 9.8 0.5 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Abhydrolase_5 PF12695.7 OAJ27455.1 - 0.054 13.3 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2721 PF11026.8 OAJ27456.1 - 0.33 10.9 1.5 0.58 10.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Syntaxin PF00804.25 OAJ27456.1 - 0.72 9.5 5.5 1.2 8.7 5.5 1.3 1 0 0 1 1 1 0 Syntaxin DivIC PF04977.15 OAJ27457.1 - 0.43 10.4 2.8 0.89 9.4 2.8 1.5 1 0 0 1 1 1 0 Septum formation initiator UPRTase PF14681.6 OAJ27458.1 - 9.5e-64 214.7 0.0 1.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 OAJ27458.1 - 2.4e-05 23.9 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ras PF00071.22 OAJ27459.1 - 3e-58 196.0 0.2 3.4e-58 195.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ27459.1 - 5.4e-20 71.8 0.0 9.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ27459.1 - 4.2e-08 32.8 0.0 5.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ27459.1 - 0.00012 21.6 0.1 0.00026 20.6 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ27459.1 - 0.00025 21.0 0.0 0.19 11.6 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ27459.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ27459.1 - 0.04 13.5 0.1 0.11 12.1 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 OAJ27459.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CbiA PF01656.23 OAJ27459.1 - 0.18 11.9 0.5 1.9 8.5 0.5 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sec23_trunk PF04811.15 OAJ27460.1 - 1.4e-75 254.1 0.0 2e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 OAJ27460.1 - 4.3e-31 107.5 0.0 7.9e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 OAJ27460.1 - 6.5e-26 90.2 0.2 1.3e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 OAJ27460.1 - 1.8e-15 56.7 5.5 3.3e-15 55.8 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ27460.1 - 6e-13 48.5 0.0 1.5e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 OAJ27460.1 - 0.08 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RF-1 PF00472.20 OAJ27461.1 - 4.6e-18 65.2 0.4 6.7e-18 64.7 0.4 1.2 1 0 0 1 1 1 1 RF-1 domain PNK3P PF08645.11 OAJ27462.1 - 1.2e-36 125.9 0.2 2e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 OAJ27462.1 - 3.2e-20 72.8 0.0 2.4e-17 63.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ27462.1 - 0.043 13.3 0.0 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OAJ27462.1 - 0.11 11.8 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 OAJ27462.1 - 0.17 12.3 0.1 14 6.1 0.0 2.4 1 1 1 2 2 2 0 AAA domain MUG113 PF13455.6 OAJ27463.1 - 3.9e-12 46.7 0.0 1.3e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 OAJ27463.1 - 3.4e-11 43.6 0.0 2.2e-10 41.0 0.0 2.4 1 1 0 1 1 1 1 T5orf172 domain SUIM_assoc PF16619.5 OAJ27463.1 - 1.6 8.9 13.8 4.1 7.6 5.3 3.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Aminotran_5 PF00266.19 OAJ27464.1 - 4.3e-31 108.2 0.1 1.1e-26 93.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ27464.1 - 8.3e-07 27.9 0.0 2.4e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_9 PF08221.11 OAJ27464.1 - 0.1 12.7 0.1 5.7 7.1 0.0 2.8 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glyco_transf_22 PF03901.17 OAJ27465.1 - 1.4e-82 278.2 12.7 4.8e-64 217.1 6.8 2.8 2 1 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 OAJ27465.1 - 5.6e-06 26.7 2.1 5.6e-06 26.7 2.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Cellulase PF00150.18 OAJ27466.1 - 5.8e-16 58.8 0.6 8.7e-16 58.2 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cyt-b5 PF00173.28 OAJ27467.1 - 3.1e-25 88.1 0.0 4.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Y_phosphatase2 PF03162.13 OAJ27468.1 - 1.4e-56 190.6 0.0 2.2e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 OAJ27468.1 - 1.4e-07 31.7 0.0 2.7e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 OAJ27468.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ27468.1 - 0.0097 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4050 PF13259.6 OAJ27468.1 - 1.3 9.4 9.4 1.1 9.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) RNA_pol_3_Rpc31 PF11705.8 OAJ27468.1 - 2.3 8.4 12.9 5.2 7.3 12.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 WD40 PF00400.32 OAJ27469.1 - 1.4e-10 41.5 0.3 9.8e-05 23.1 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27469.1 - 4.9e-05 23.5 0.0 0.14 12.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3123 PF11321.8 OAJ27469.1 - 0.057 14.1 0.4 0.15 12.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) fn3_2 PF16893.5 OAJ27470.1 - 2.1e-37 127.2 0.1 3.3e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 OAJ27470.1 - 1.1e-25 89.3 0.1 2.2e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 OAJ27470.1 - 4.8e-08 33.3 0.0 8.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ27470.1 - 5.8e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 OAJ27470.1 - 5.2e-05 23.4 0.0 5.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 OAJ27470.1 - 0.0019 18.5 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 OAJ27470.1 - 0.0023 18.3 0.3 0.0097 16.2 0.3 2.0 1 1 0 1 1 1 1 Fibronectin type III domain Myc_N PF01056.18 OAJ27470.1 - 0.41 10.5 7.1 0.72 9.7 7.1 1.5 1 1 0 1 1 1 0 Myc amino-terminal region dCMP_cyt_deam_1 PF00383.23 OAJ27471.1 - 2.8e-20 72.1 0.0 4.4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ27471.1 - 7.7e-19 67.8 0.2 9.5e-18 64.3 0.2 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAJ27471.1 - 2.4e-05 24.4 0.0 3.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase DDHD PF02862.17 OAJ27475.1 - 6.7e-22 78.7 14.8 8.4e-22 78.4 0.0 3.3 2 1 0 2 2 2 1 DDHD domain Tetraspanin PF00335.20 OAJ27476.1 - 1.9e-06 27.8 0.8 1.9e-06 27.8 0.8 1.9 1 1 1 2 2 2 1 Tetraspanin family Shisa PF13908.6 OAJ27476.1 - 0.00063 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3357 PF11837.8 OAJ27476.1 - 0.062 13.8 0.6 26 5.3 0.0 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF2569 PF10754.9 OAJ27476.1 - 0.25 11.8 7.6 0.15 12.5 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2207 PF09972.9 OAJ27476.1 - 4.3 6.0 4.6 42 2.7 4.7 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4389 PF14333.6 OAJ27476.1 - 6.5 6.8 6.3 9 6.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) zf-HIT PF04438.16 OAJ27477.1 - 6.7e-09 35.5 10.3 9.5e-09 35.0 10.3 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 OAJ27477.1 - 1.4 9.2 4.9 2.3 8.5 4.9 1.3 1 0 0 1 1 1 0 B-box zinc finger CDP-OH_P_transf PF01066.21 OAJ27479.1 - 1.4e-12 48.2 0.2 3.4e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pkinase PF00069.25 OAJ27480.1 - 3.1e-49 167.7 0.0 8.9e-49 166.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27480.1 - 3.2e-20 72.5 0.0 1.4e-19 70.4 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ27480.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIP49 PF06068.13 OAJ27481.1 - 4.7e-150 499.6 0.0 6.3e-150 499.2 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 OAJ27481.1 - 6.6e-24 83.8 1.5 3.3e-23 81.6 1.5 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 OAJ27481.1 - 4.9e-12 46.4 0.7 4e-09 37.0 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 OAJ27481.1 - 6.7e-12 45.4 1.6 1.1e-08 34.9 0.1 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ27481.1 - 5e-07 30.3 0.1 1.8e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 OAJ27481.1 - 1.6e-06 27.7 0.3 3e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 OAJ27481.1 - 1.7e-06 28.4 0.1 0.084 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ27481.1 - 7.9e-06 25.9 0.2 0.0038 17.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ27481.1 - 1.3e-05 24.7 0.7 0.00051 19.5 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 OAJ27481.1 - 1.9e-05 25.0 0.3 0.00016 22.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 OAJ27481.1 - 4.3e-05 23.3 0.1 0.066 12.9 0.1 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 OAJ27481.1 - 0.0006 19.4 0.3 0.0025 17.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 OAJ27481.1 - 0.00069 18.8 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 OAJ27481.1 - 0.00073 20.0 0.1 0.0017 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 OAJ27481.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 OAJ27481.1 - 0.0021 18.0 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 OAJ27481.1 - 0.0029 18.2 1.8 0.0043 17.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAJ27481.1 - 0.0047 16.5 0.1 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 OAJ27481.1 - 0.006 16.6 0.0 7.2 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 OAJ27481.1 - 0.0068 16.1 0.3 0.17 11.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 OAJ27481.1 - 0.0072 16.3 0.3 0.018 15.0 0.0 1.8 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ27481.1 - 0.0087 16.2 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ27481.1 - 0.0099 15.7 0.2 0.021 14.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAJ27481.1 - 0.011 15.0 0.3 0.039 13.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ27481.1 - 0.012 15.6 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 OAJ27481.1 - 0.017 14.4 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 OAJ27481.1 - 0.02 15.4 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 OAJ27481.1 - 0.02 15.0 0.0 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PIF1 PF05970.14 OAJ27481.1 - 0.021 14.0 0.6 0.89 8.6 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.16 OAJ27481.1 - 0.026 14.0 0.1 0.069 12.6 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 OAJ27481.1 - 0.029 14.6 0.1 0.078 13.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 OAJ27481.1 - 0.037 14.2 0.2 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 OAJ27481.1 - 0.047 13.6 0.4 0.19 11.6 0.1 2.3 2 1 0 2 2 1 0 NTPase RNA_helicase PF00910.22 OAJ27481.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 OAJ27481.1 - 0.097 12.4 0.2 2.8 7.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain ACC_central PF08326.12 OAJ27482.1 - 1.5e-194 648.3 0.0 1.9e-194 647.9 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 OAJ27482.1 - 2.6e-165 550.8 0.0 3.5e-165 550.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 OAJ27482.1 - 1.5e-52 178.1 0.0 3.3e-52 177.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAJ27482.1 - 2e-28 99.1 0.1 6.4e-28 97.5 0.1 2.0 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ27482.1 - 7.4e-22 77.5 0.0 3e-20 72.3 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ27482.1 - 3.9e-15 55.4 0.2 7.7e-15 54.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ27482.1 - 2.2e-06 27.4 0.0 6.5e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like RnfC_N PF13375.6 OAJ27482.1 - 0.0032 17.4 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain SEP PF08059.13 OAJ27483.1 - 3.8e-19 69.0 0.0 7.9e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 OAJ27483.1 - 1.9e-13 50.4 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 OAJ27483.1 - 9.4e-10 38.2 1.7 1.7e-09 37.4 1.7 1.4 1 0 0 1 1 1 1 UBA-like domain SUR7 PF06687.12 OAJ27484.1 - 3.4e-16 59.5 13.4 4.5e-16 59.1 13.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4763 PF15960.5 OAJ27484.1 - 0.22 10.8 0.4 0.31 10.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) JAB PF01398.21 OAJ27485.1 - 3.5e-16 59.2 0.0 3.3e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ27485.1 - 3.6e-13 49.9 0.1 6.3e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function LSM PF01423.22 OAJ27486.1 - 9.7e-22 76.4 0.4 1.1e-21 76.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ27486.1 - 0.009 16.1 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_L16 PF00252.18 OAJ27487.1 - 5e-41 139.8 0.4 6.7e-41 139.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PX PF00787.24 OAJ27488.1 - 1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 PX domain INCA1 PF15142.6 OAJ27489.1 - 0.0062 16.6 2.4 0.49 10.4 0.0 2.9 2 1 1 3 3 3 2 INCA1 YL1 PF05764.13 OAJ27489.1 - 8.3 6.4 9.8 5.2 7.1 1.7 2.6 2 1 0 2 2 2 0 YL1 nuclear protein Bap31 PF05529.12 OAJ27490.1 - 2.4e-44 150.5 10.9 2.4e-44 150.5 10.9 1.4 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 OAJ27490.1 - 0.00021 21.2 7.4 0.00035 20.5 7.4 1.5 1 1 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain HMG_box PF00505.19 OAJ27490.1 - 0.22 12.0 1.8 0.4 11.1 1.8 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box TFIIF_beta_N PF17683.1 OAJ27491.1 - 2.9e-14 53.9 0.0 4.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus V-SNARE_C PF12352.8 OAJ27492.1 - 0.11 12.8 0.3 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Peptidase_S8 PF00082.22 OAJ27493.1 - 1.2e-56 192.1 1.7 1.9e-56 191.5 1.7 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 OAJ27493.1 - 9.5e-40 136.1 0.0 1.4e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II Ribosomal_L37 PF08561.10 OAJ27494.1 - 1.9e-25 89.7 3.9 1.9e-25 89.7 3.9 2.2 2 1 0 2 2 2 1 Mitochondrial ribosomal protein L37 PPP1R35_C PF15503.6 OAJ27494.1 - 0.021 14.6 5.1 0.042 13.7 5.1 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus SPX PF03105.19 OAJ27496.1 - 0.68 9.8 6.0 0.3 10.9 2.9 1.8 2 0 0 2 2 2 0 SPX domain SHQ1 PF04925.15 OAJ27497.1 - 2.6e-22 79.2 0.0 1.6e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 SHQ1 protein YuzL PF14115.6 OAJ27497.1 - 1.1 9.8 4.1 4.1 8.0 4.1 2.0 1 0 0 1 1 1 0 YuzL-like protein PPP4R2 PF09184.11 OAJ27497.1 - 1.8 8.1 3.9 2.7 7.5 3.9 1.1 1 0 0 1 1 1 0 PPP4R2 DASH_Hsk3 PF08227.11 OAJ27498.1 - 2.9e-07 30.7 3.0 4.2e-07 30.2 3.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Cys_Met_Meta_PP PF01053.20 OAJ27500.1 - 4.2e-96 321.8 0.0 4.7e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 OAJ27500.1 - 2e-10 40.4 0.1 2.5e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ27500.1 - 1.2e-09 37.6 0.3 1.6e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAJ27500.1 - 1.5e-09 37.6 0.2 2.5e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 OAJ27500.1 - 3.4e-05 22.6 0.0 4.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 OAJ27500.1 - 0.00073 18.9 0.1 0.002 17.5 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 OAJ27500.1 - 0.23 10.1 0.1 0.29 9.8 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 OAJ27501.1 - 3.2e-87 292.9 0.0 4.8e-87 292.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ27501.1 - 0.00021 20.6 0.2 0.00036 19.9 0.2 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAJ27501.1 - 0.08 11.5 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Gpr1_Fun34_YaaH PF01184.19 OAJ27502.1 - 4.7e-45 153.7 8.2 5.8e-45 153.5 8.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2417 PF10329.9 OAJ27502.1 - 0.015 14.7 3.4 1.2 8.5 0.0 2.2 1 1 0 2 2 2 0 Region of unknown function (DUF2417) RRM_1 PF00076.22 OAJ27503.1 - 1.8e-26 91.8 0.1 2.9e-12 46.2 0.0 5.2 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ27503.1 - 0.00045 20.3 0.0 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 OAJ27503.1 - 0.0097 15.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RhoGAP PF00620.27 OAJ27504.1 - 2e-37 128.3 0.1 4.6e-37 127.2 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 OAJ27504.1 - 3.9e-23 81.4 33.8 7.6e-10 38.9 6.3 5.1 5 0 0 5 5 5 4 LIM domain Ribosomal_L28e PF01778.17 OAJ27505.1 - 6.7e-35 120.3 1.7 8.4e-35 120.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 OAJ27505.1 - 4.5e-23 81.7 30.3 4.5e-23 81.7 30.3 3.3 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 OAJ27505.1 - 1.2e-06 28.2 25.5 1.6e-06 27.8 25.5 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 OAJ27505.1 - 0.0076 16.0 2.3 0.013 15.3 2.3 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain TFIIA PF03153.13 OAJ27505.1 - 0.14 12.2 17.8 0.2 11.6 17.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 OAJ27505.1 - 0.83 7.8 38.4 1.1 7.4 38.4 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 OAJ27505.1 - 1 8.0 12.3 1.4 7.6 12.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MSA_2 PF00985.17 OAJ27506.1 - 0.0027 18.1 0.5 0.0028 18.0 0.5 1.0 1 0 0 1 1 1 1 Merozoite Surface Antigen 2 (MSA-2) family CPSF73-100_C PF11718.8 OAJ27507.1 - 6.4e-55 186.0 2.4 6.4e-55 186.0 2.4 2.5 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 OAJ27507.1 - 1.1e-29 102.9 0.0 2.5e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 OAJ27507.1 - 1.1e-18 67.3 0.0 2.2e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 OAJ27507.1 - 7.6e-18 65.2 0.8 7.6e-18 65.2 0.8 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 OAJ27507.1 - 5.4e-16 58.3 0.2 1.1e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 OAJ27507.1 - 6.8e-08 32.3 0.9 6.2e-07 29.1 0.5 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ27507.1 - 6.8e-07 29.3 0.1 2.9e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Thg1 PF04446.12 OAJ27509.1 - 7.1e-49 165.0 0.0 1.1e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 OAJ27509.1 - 8.1e-44 148.7 0.0 1.4e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain cNMP_binding PF00027.29 OAJ27510.1 - 1.6e-25 89.0 0.0 6.7e-14 51.7 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 OAJ27510.1 - 6.8e-18 65.6 4.5 1.6e-11 44.8 1.2 3.2 3 0 0 3 3 3 2 Patatin-like phospholipase Ribonuclease_3 PF00636.26 OAJ27513.1 - 1.3e-09 38.6 0.0 1.9e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ27513.1 - 0.0024 18.0 0.2 0.0047 17.1 0.1 1.4 2 0 0 2 2 2 1 Ribonuclease-III-like Peptidase_S8 PF00082.22 OAJ27514.1 - 2e-40 138.9 0.0 4.7e-40 137.7 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ27514.1 - 3.7e-15 56.6 0.0 1.2e-14 54.9 0.0 2.0 1 0 0 1 1 1 1 Fn3-like domain DPBB_1 PF03330.18 OAJ27515.1 - 0.00016 21.9 0.7 0.00063 20.0 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ27515.1 - 0.001 18.9 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Barwin family Glycogen_syn PF05693.13 OAJ27517.1 - 0 1130.7 0.0 0 1130.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 OAJ27517.1 - 9.8e-08 31.7 0.0 0.00011 21.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 OAJ27517.1 - 2.9e-06 27.2 0.1 7.7e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 OAJ27517.1 - 3.3e-06 27.6 0.0 0.0045 17.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ27517.1 - 4.1e-05 23.7 0.2 7.6e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ27517.1 - 0.00019 21.9 0.0 0.00043 20.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Caleosin PF05042.13 OAJ27518.1 - 2.2e-65 219.7 0.2 2.7e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 Caleosin related protein DUF3384 PF11864.8 OAJ27519.1 - 1.8e-59 202.0 0.0 2.1e-58 198.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 OAJ27519.1 - 1.5e-42 145.2 0.0 2.6e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 OAJ27519.1 - 2.1e-31 109.3 4.7 2.9e-28 99.0 4.8 3.0 2 1 0 2 2 2 2 Tuberin NDC10_II PF16787.5 OAJ27520.1 - 0.001 18.2 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 rve PF00665.26 OAJ27521.1 - 2.7e-06 27.6 0.2 8.5e-06 25.9 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain Helitron_like_N PF14214.6 OAJ27523.1 - 8.6e-21 75.0 0.0 1.4e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF883 PF05957.13 OAJ27524.1 - 0.0018 18.8 1.6 0.88 10.2 0.5 2.3 1 1 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 OAJ27524.1 - 0.0026 17.7 3.6 0.01 15.7 3.6 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3150 PF11348.8 OAJ27524.1 - 0.065 12.5 0.2 0.09 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF4164 PF13747.6 OAJ27524.1 - 0.1 12.9 2.3 0.21 11.9 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF842 PF05811.13 OAJ27524.1 - 0.37 10.5 2.4 9.3 6.0 1.3 2.6 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Mst1_SARAH PF11629.8 OAJ27524.1 - 1.4 9.0 4.3 8.4 6.6 0.2 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 FA_hydroxylase PF04116.13 OAJ27526.1 - 1.8e-19 70.4 17.9 1.8e-19 70.4 17.9 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3360 PF11840.8 OAJ27526.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) API5 PF05918.11 OAJ27526.1 - 2.4 6.9 6.1 3.3 6.4 6.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_S6 PF01250.17 OAJ27527.1 - 1.7e-23 82.7 0.0 2.2e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 UQ_con PF00179.26 OAJ27528.1 - 1.5e-17 63.5 0.0 2.6e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-4CXXC_R1 PF10497.9 OAJ27528.1 - 0.012 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RWD PF05773.22 OAJ27528.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 RWD domain CLTH PF10607.9 OAJ27529.1 - 1.2e-18 67.4 0.0 2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 OAJ27529.1 - 0.032 14.2 0.2 0.088 12.8 0.2 1.8 1 0 0 1 1 1 0 LisH RT_RNaseH PF17917.1 OAJ27531.1 - 4.9e-13 49.3 0.0 6.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ27531.1 - 8.2e-08 32.2 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ27533.1 - 8e-10 38.9 0.0 2.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ27533.1 - 2.7e-05 24.4 0.0 5.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ27533.1 - 0.0002 21.3 0.0 0.00056 19.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Alg14 PF08660.11 OAJ27534.1 - 1.9e-49 168.0 0.0 5.7e-49 166.4 0.0 1.7 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like RPA43_OB PF17875.1 OAJ27535.1 - 2e-14 54.3 0.0 2e-14 54.3 0.0 3.8 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 OAJ27535.1 - 2.8e-06 27.6 0.0 6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cwf_Cwc_15 PF04889.12 OAJ27535.1 - 0.00012 21.9 21.4 0.00012 21.9 21.4 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 OAJ27535.1 - 1.8 8.3 27.8 0.045 13.6 18.5 2.2 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Chitin_synth_2 PF03142.15 OAJ27536.1 - 1.3e-236 786.3 0.0 1.8e-236 785.8 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 OAJ27536.1 - 2.9e-11 43.7 0.4 1.6e-10 41.3 0.2 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ27536.1 - 2.9e-10 40.4 10.8 2.9e-10 40.4 10.8 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 DUF3149 PF11346.8 OAJ27536.1 - 0.4 10.3 4.8 1.6 8.4 4.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Atg14 PF10186.9 OAJ27538.1 - 1e-07 31.4 6.2 2.2e-07 30.3 6.2 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ALO PF04030.14 OAJ27538.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase DUF202 PF02656.15 OAJ27539.1 - 9.6e-06 26.0 4.0 4.1e-05 24.0 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TC1 PF15063.6 OAJ27539.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Thyroid cancer protein 1 Ctr PF04145.15 OAJ27539.1 - 0.065 13.9 0.1 0.11 13.1 0.1 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Tom5 PF10642.9 OAJ27540.1 - 0.18 11.9 4.7 2.6 8.2 1.5 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase TPR_MLP1_2 PF07926.12 OAJ27542.1 - 4e-26 91.6 20.2 4e-26 91.6 20.2 19.6 7 5 11 18 18 18 7 TPR/MLP1/MLP2-like protein GRASP55_65 PF04495.14 OAJ27543.1 - 7.8e-56 188.2 0.0 2.6e-48 163.9 0.0 2.4 2 1 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 OAJ27543.1 - 0.0014 18.4 0.2 0.5 10.3 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 OAJ27543.1 - 0.016 15.5 0.0 11 6.4 0.0 3.3 3 1 0 3 3 3 0 PDZ domain Myc_N PF01056.18 OAJ27543.1 - 0.085 12.7 1.4 0.13 12.1 1.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 OAJ27543.1 - 1.6 9.4 12.8 0.13 12.8 5.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein CDC45 PF02724.14 OAJ27544.1 - 3.6 5.8 12.1 5.6 5.1 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 OAJ27545.1 - 1e-29 101.1 20.9 2.5e-06 27.0 1.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ27545.1 - 1.1e-29 100.1 22.5 3.1e-05 23.7 0.0 11.0 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ27545.1 - 3.2e-22 77.2 11.5 1.9e-05 24.7 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ27545.1 - 3.3e-22 78.8 14.0 7.5e-07 29.7 0.0 6.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27545.1 - 1.8e-21 74.4 18.8 1.5e-05 24.8 0.1 8.8 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ27545.1 - 1.4e-17 63.7 17.8 9.5e-05 22.6 0.0 7.9 4 2 5 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ27545.1 - 5.8e-17 61.1 21.9 4.3e-07 29.5 0.0 7.8 5 2 3 8 8 7 5 TPR repeat TPR_14 PF13428.6 OAJ27545.1 - 8.3e-14 51.1 16.2 3.1e-05 24.4 0.0 8.8 2 2 8 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ27545.1 - 2.3e-13 50.4 21.8 7.2e-05 23.2 1.0 6.5 4 2 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27545.1 - 5.4e-12 45.7 7.3 1.6e-05 25.0 0.1 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ27545.1 - 1.4e-10 41.2 12.1 0.00055 20.1 0.1 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 OAJ27545.1 - 5.7e-08 32.3 15.7 0.37 10.9 0.1 7.5 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ27545.1 - 1.7e-05 24.4 1.2 0.00015 21.3 0.1 2.9 3 1 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 OAJ27545.1 - 0.00015 22.0 10.5 0.057 13.8 0.0 5.3 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ27545.1 - 0.00053 19.3 10.6 0.073 12.3 1.7 4.2 2 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ27545.1 - 0.0028 17.5 18.4 12 5.9 0.0 8.2 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ27545.1 - 0.021 14.9 10.9 0.15 12.1 0.0 5.0 4 2 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 OAJ27545.1 - 0.021 15.4 1.3 23 6.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 OAJ27545.1 - 0.058 13.5 0.2 1.4 9.1 0.0 3.1 4 0 0 4 4 3 0 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.12 OAJ27545.1 - 6.4 6.9 7.1 3.4 7.7 0.6 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_2 PF00891.18 OAJ27546.1 - 1.3e-23 83.4 0.0 2.8e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Rrf2 PF02082.20 OAJ27546.1 - 0.021 15.2 0.0 6.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Transcriptional regulator Methyltransf_25 PF13649.6 OAJ27546.1 - 0.022 15.4 0.0 0.053 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ndc1_Nup PF09531.10 OAJ27547.1 - 8.9 4.9 9.0 12 4.5 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA-synt_2c PF01411.19 OAJ27550.1 - 4.9e-212 705.3 0.0 7.9e-212 704.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 OAJ27550.1 - 4.6e-17 61.8 0.2 1.1e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 OAJ27550.1 - 0.12 12.8 8.9 1.7 9.0 8.7 2.6 1 1 0 1 1 1 0 DHHA1 domain RPEL PF02755.15 OAJ27551.1 - 0.059 13.1 0.0 15 5.4 0.1 2.5 2 0 0 2 2 2 0 RPEL repeat cobW PF02492.19 OAJ27552.1 - 1.9e-43 148.1 4.3 2.1e-42 144.7 4.3 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 OAJ27552.1 - 7.5e-18 64.3 0.2 2e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 OAJ27552.1 - 0.017 15.0 0.6 3.8 7.4 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 OAJ27552.1 - 0.029 14.7 0.6 0.46 10.7 0.6 2.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 OAJ27552.1 - 0.033 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SDA1 PF05285.12 OAJ27552.1 - 0.033 13.6 3.1 0.077 12.4 3.1 1.5 1 1 0 1 1 1 0 SDA1 MobB PF03205.14 OAJ27552.1 - 0.054 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 OAJ27552.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 OAJ27552.1 - 0.12 12.4 0.1 0.64 10.1 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 OAJ27552.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 OAJ27552.1 - 0.17 10.2 1.8 0.24 9.7 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ27552.1 - 0.93 9.6 6.3 1.9 8.6 6.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein AAA_16 PF13191.6 OAJ27552.1 - 1.2 9.5 3.0 1 9.7 0.4 2.5 3 1 0 3 3 3 0 AAA ATPase domain RRN3 PF05327.11 OAJ27552.1 - 1.2 7.6 3.9 2.6 6.5 3.9 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ27552.1 - 8.8 4.3 12.9 14 3.6 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_N PF01194.17 OAJ27553.1 - 3.5e-26 91.3 0.3 4.6e-26 90.9 0.3 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Pkinase PF00069.25 OAJ27554.1 - 9.5e-60 202.2 0.0 1.2e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27554.1 - 2.6e-38 131.8 0.0 3.4e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ27554.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ27554.1 - 0.0023 17.0 0.0 0.0046 16.0 0.0 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ27554.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 OAJ27554.1 - 0.026 14.4 0.1 0.31 10.9 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family PAPS_reduct PF01507.19 OAJ27555.1 - 3.7e-20 72.7 0.0 6.4e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF2235 PF09994.9 OAJ27556.1 - 2.2e-65 220.9 0.0 3.6e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAJ27557.1 - 2.1e-64 217.7 0.0 3.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tim17 PF02466.19 OAJ27558.1 - 7.2e-19 68.2 8.2 1.1e-18 67.6 8.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pex14_N PF04695.13 OAJ27558.1 - 1.3 9.7 11.0 2.2 8.9 11.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK2AP PF09806.9 OAJ27558.1 - 1.4 8.9 6.2 2.1 8.4 6.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2235 PF09994.9 OAJ27559.1 - 2e-73 247.3 0.0 2.6e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Pkinase PF00069.25 OAJ27560.1 - 5e-73 245.7 0.1 5e-73 245.7 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27560.1 - 2.8e-52 177.6 1.1 6.5e-52 176.4 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 OAJ27560.1 - 1.4e-22 79.7 0.0 3.5e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 OAJ27560.1 - 1.8e-11 44.5 0.9 3.9e-11 43.4 0.9 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 OAJ27560.1 - 1.3e-06 27.4 1.0 4.2e-06 25.8 1.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ27560.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ27560.1 - 0.0011 17.9 1.3 0.0018 17.3 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain PH_11 PF15413.6 OAJ27560.1 - 0.0028 18.1 1.1 0.18 12.2 1.1 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 OAJ27560.1 - 0.027 14.4 6.8 0.037 13.9 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAT1 PF06391.13 OAJ27560.1 - 0.88 9.4 6.1 1.5 8.6 6.1 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF3915 PF13054.6 OAJ27560.1 - 1.4 8.9 8.9 2.8 7.9 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Rotamase PF00639.21 OAJ27560.1 - 2.8 8.9 8.1 7.6 7.6 8.1 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain RR_TM4-6 PF06459.12 OAJ27560.1 - 3.3 7.5 8.2 5.9 6.6 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_32N PF00251.20 OAJ27561.1 - 1.9e-36 126.2 0.0 5.7e-25 88.5 0.4 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ27561.1 - 1.9e-21 76.7 0.0 3.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Gpr1_Fun34_YaaH PF01184.19 OAJ27563.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family TPR_1 PF00515.28 OAJ27564.1 - 1.9e-57 188.8 14.5 4e-07 29.6 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ27564.1 - 2.1e-51 167.9 14.0 5.1e-06 26.2 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27564.1 - 3e-38 126.8 10.1 9.3e-05 22.3 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ27564.1 - 3.8e-29 100.1 22.9 6.7e-07 28.9 0.1 9.3 5 3 4 9 9 9 7 TPR repeat TPR_16 PF13432.6 OAJ27564.1 - 3.6e-28 97.9 12.6 1.9e-06 28.4 0.0 7.7 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ27564.1 - 1.1e-27 94.3 15.2 0.0006 20.0 0.3 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ27564.1 - 2.1e-27 95.4 8.6 4.3e-06 27.1 0.3 6.7 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ27564.1 - 2.6e-27 93.2 10.2 0.002 18.8 0.0 9.6 3 2 6 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ27564.1 - 4e-25 86.0 6.5 0.027 14.5 0.0 9.6 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ27564.1 - 2.9e-23 81.9 11.6 8.1e-05 22.8 0.1 7.2 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ27564.1 - 5.7e-20 70.6 10.4 0.011 16.3 0.0 10.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27564.1 - 4.3e-18 65.2 10.3 0.0034 17.5 0.2 6.9 1 1 2 6 6 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ27564.1 - 3.7e-14 52.7 7.3 1.3e-07 31.7 0.7 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAJ27564.1 - 2.8e-06 26.7 9.2 0.034 13.4 0.9 5.1 1 1 5 6 6 6 2 Tetratricopeptide repeat DUF4919 PF16266.5 OAJ27564.1 - 4.6e-05 23.4 0.8 0.016 15.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_10 PF13374.6 OAJ27564.1 - 0.00029 20.6 18.4 0.52 10.2 0.2 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TOM20_plant PF06552.12 OAJ27564.1 - 0.02 14.6 0.5 7.4 6.3 0.0 3.5 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 ChAPs PF09295.10 OAJ27564.1 - 0.039 13.0 1.1 6.2 5.7 0.2 2.3 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 OAJ27564.1 - 0.047 14.0 0.0 0.047 14.0 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 OAJ27564.1 - 0.62 10.5 15.6 0.22 11.9 0.6 4.0 3 1 1 4 4 3 0 Bacterial transcriptional activator domain UCH PF00443.29 OAJ27566.1 - 3.6e-64 216.7 0.0 5.7e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ27566.1 - 1e-20 74.6 0.0 2.8e-17 63.3 0.0 2.8 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 OAJ27566.1 - 2.5e-07 30.9 1.1 6.7e-07 29.5 1.1 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 OAJ27566.1 - 0.0084 16.6 0.0 0.057 13.9 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain DUF104 PF01954.16 OAJ27566.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF104 zf-MIZ PF02891.20 OAJ27566.1 - 0.28 10.9 0.7 0.54 10.1 0.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Paramyxo_P_V_N PF13825.6 OAJ27566.1 - 0.82 9.0 7.3 2.4 7.5 0.6 2.3 2 0 0 2 2 2 0 Paramyxovirus structural protein V/P N-terminus Bestrophin PF01062.21 OAJ27567.1 - 3.9e-33 115.1 0.1 6.6e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sec1 PF00995.23 OAJ27568.1 - 4.4e-71 240.8 0.0 8.1e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 Sec1 family DUF572 PF04502.13 OAJ27569.1 - 2.6 7.6 8.0 1.4 8.5 4.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Transposase_21 PF02992.14 OAJ27571.1 - 9.5e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 Nop14 PF04147.12 OAJ27571.1 - 0.5 8.5 7.5 0.65 8.1 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ27573.1 - 0.064 11.8 5.6 0.079 11.5 5.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.29 OAJ27574.1 - 0.0021 18.5 0.0 0.0021 18.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3435 PF11917.8 OAJ27575.1 - 0.00026 20.0 0.0 0.00034 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Lyase_aromatic PF00221.19 OAJ27576.1 - 5.3e-151 503.4 6.2 6.9e-151 503.0 6.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase G-patch PF01585.23 OAJ27577.1 - 2.9e-14 52.7 0.7 2.9e-14 52.7 0.7 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ27577.1 - 0.00017 21.6 0.3 0.00017 21.6 0.3 3.3 3 1 0 3 3 3 1 G-patch domain CDC45 PF02724.14 OAJ27577.1 - 0.0028 16.0 7.6 0.0028 16.0 7.6 2.1 2 0 0 2 2 2 1 CDC45-like protein DUF3340 PF11818.8 OAJ27577.1 - 0.39 10.8 17.2 0.44 10.7 7.7 2.5 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) EOS1 PF12326.8 OAJ27577.1 - 2.6 7.9 5.5 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 N-glycosylation protein TT_ORF2 PF02957.15 OAJ27578.1 - 0.18 12.7 3.1 0.18 12.7 0.2 2.2 1 1 1 2 2 2 0 TT viral ORF2 PH PF00169.29 OAJ27579.1 - 7.6e-05 23.2 0.0 0.00049 20.6 0.0 2.3 1 1 0 1 1 1 1 PH domain Cauli_VI PF01693.16 OAJ27580.1 - 1.2e-05 25.5 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RVT_3 PF13456.6 OAJ27580.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like SURF2 PF05477.11 OAJ27580.1 - 2.3 7.9 5.2 3.6 7.2 5.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) She9_MDM33 PF05546.11 OAJ27581.1 - 2.4e-60 203.7 7.6 2.4e-60 203.7 7.6 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family DUF2207 PF09972.9 OAJ27581.1 - 0.035 12.9 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GDC-P PF02347.16 OAJ27582.1 - 5.4e-182 605.4 0.0 3.5e-171 569.8 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 OAJ27582.1 - 0.0062 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase SGL PF08450.12 OAJ27583.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF2857 PF11198.8 OAJ27584.1 - 0.014 15.2 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) TetR_C_27 PF17935.1 OAJ27584.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sipho_Gp157 PF05565.11 OAJ27584.1 - 0.026 14.5 0.6 0.032 14.2 0.6 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 PhaP_Bmeg PF09602.10 OAJ27584.1 - 0.068 13.1 0.1 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) HsbA PF12296.8 OAJ27585.1 - 1e-19 71.1 15.6 1e-19 71.1 15.6 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A DUF1326 PF07040.11 OAJ27585.1 - 0.036 14.1 0.6 0.055 13.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1326) Baculo_PEP_C PF04513.12 OAJ27585.1 - 0.21 11.6 7.6 0.26 11.3 7.3 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Iso_dh PF00180.20 OAJ27586.1 - 1.2e-102 343.6 0.0 1.7e-102 343.2 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PhzC-PhzF PF02567.16 OAJ27587.1 - 3.8e-38 131.6 0.0 4.4e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 OAJ27587.1 - 0.0024 17.0 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Proline racemase Fungal_trans PF04082.18 OAJ27588.1 - 2.1e-09 36.8 0.1 3.1e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ27588.1 - 0.0035 17.4 2.0 0.0061 16.7 2.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 OAJ27588.1 - 0.73 10.5 8.1 2.1 9.0 8.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.7 OAJ27589.1 - 7.5e-09 35.3 1.6 1.8e-08 34.2 1.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ27589.1 - 5.3e-07 29.3 1.2 9.2e-07 28.6 1.2 1.4 1 0 0 1 1 1 1 F-box domain Jacalin PF01419.17 OAJ27591.1 - 2.1e-05 24.4 0.0 0.0032 17.4 0.0 2.8 2 1 0 2 2 2 2 Jacalin-like lectin domain FAP206 PF12018.8 OAJ27591.1 - 0.0086 15.6 1.4 0.065 12.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function DpnI_C PF17726.1 OAJ27592.1 - 0.076 13.2 0.3 0.17 12.1 0.2 1.7 1 1 0 1 1 1 0 Dam-replacing HTH domain Pox_A21 PF05323.12 OAJ27592.1 - 0.086 13.4 0.1 0.17 12.5 0.1 1.5 1 1 0 1 1 1 0 Poxvirus A21 Protein H_lectin PF09458.10 OAJ27593.1 - 0.00071 19.7 1.8 0.065 13.4 0.0 3.6 4 0 0 4 4 4 2 H-type lectin domain URO-D PF01208.17 OAJ27594.1 - 1.4e-135 451.9 0.0 1.6e-135 451.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L11_N PF03946.14 OAJ27595.1 - 5.7e-24 83.7 0.2 9.1e-24 83.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ27595.1 - 2.1e-16 60.2 0.1 3.8e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HnRNP_M PF11532.8 OAJ27595.1 - 0.0088 16.2 0.8 0.015 15.5 0.8 1.3 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein M Mg_trans_NIPA PF05653.14 OAJ27596.1 - 2.2e-105 352.0 17.3 2.6e-105 351.8 17.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ27596.1 - 5.1e-05 23.5 5.2 5.1e-05 23.5 5.2 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF3671 PF12420.8 OAJ27596.1 - 5.8 7.0 11.3 0.66 10.1 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function WD40 PF00400.32 OAJ27597.1 - 4.9e-14 52.5 6.8 0.014 16.2 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27597.1 - 3.4e-10 40.1 0.0 3.2e-05 24.2 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 OAJ27597.1 - 0.012 15.5 0.2 0.33 10.9 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PI3_PI4_kinase PF00454.27 OAJ27598.1 - 8.5e-65 219.0 0.1 1.3e-64 218.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAJ27598.1 - 3.2e-45 154.9 0.0 4.6e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OAJ27598.1 - 2.5e-41 140.1 1.1 6.2e-41 138.8 1.1 1.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OAJ27598.1 - 1.1e-09 37.9 0.0 3.4e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPT PF03151.16 OAJ27599.1 - 7.6e-23 81.3 17.0 9e-23 81.0 17.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family zf-met2 PF12907.7 OAJ27600.1 - 1.5e-12 47.4 0.9 2.4e-12 46.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 OAJ27600.1 - 1.9e-08 35.1 10.0 1.9e-08 35.1 10.0 1.6 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_4 PF13894.6 OAJ27600.1 - 0.014 16.2 0.4 0.026 15.3 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger PI3_PI4_kinase PF00454.27 OAJ27601.1 - 1.5e-66 224.8 0.2 2.1e-66 224.3 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAJ27601.1 - 5.3e-43 147.5 0.0 8.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 OAJ27601.1 - 7.4e-24 84.0 0.3 1.9e-23 82.8 0.3 1.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 OAJ27601.1 - 7.6e-10 38.4 0.1 2e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain TFIID-18kDa PF02269.16 OAJ27601.1 - 0.055 13.5 0.1 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Nipped-B_C PF12830.7 OAJ27601.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus IMS PF00817.20 OAJ27602.1 - 2e-36 125.3 0.0 4.9e-36 124.0 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ27602.1 - 9.3e-07 29.6 0.0 3e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ27602.1 - 0.04 14.2 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif zf_UBZ PF18439.1 OAJ27602.1 - 0.19 11.3 4.9 2.5 7.8 1.7 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger COQ9 PF08511.11 OAJ27603.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 COQ9 Zn_clus PF00172.18 OAJ27604.1 - 2.5e-07 30.7 8.2 4.6e-07 29.8 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ27604.1 - 3.4e-07 29.6 0.0 6.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dickkopf_N PF04706.12 OAJ27604.1 - 1.2 9.7 9.5 2.5 8.6 9.5 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Sec20 PF03908.13 OAJ27605.1 - 4.7e-20 71.3 0.7 4.7e-20 71.3 0.7 1.9 2 0 0 2 2 2 1 Sec20 DUF4813 PF16072.5 OAJ27605.1 - 3.3 7.3 22.3 6.4 6.3 22.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DNA_ligase_A_N PF04675.14 OAJ27606.1 - 1.4e-08 35.2 0.0 1.9e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus Fungal_trans PF04082.18 OAJ27607.1 - 3e-08 33.0 0.0 7.1e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ27607.1 - 1.1e-07 31.9 6.2 1.8e-07 31.2 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PsbQ PF05757.11 OAJ27607.1 - 2.5 7.8 12.8 0.47 10.2 1.6 3.0 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF4448 PF14610.6 OAJ27609.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) RNase_H PF00075.24 OAJ27612.1 - 9.4e-13 48.6 0.1 2.1e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 OAJ27612.1 - 3.9e-06 26.7 0.0 9.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like MOFRL PF05161.13 OAJ27612.1 - 0.05 13.8 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 MOFRL family 2Fe-2S_thioredx PF01257.19 OAJ27614.1 - 3.6e-59 198.8 0.1 4.5e-59 198.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin RT_RNaseH PF17917.1 OAJ27616.1 - 7.1e-10 39.1 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ27616.1 - 7.5e-07 29.4 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ27616.1 - 0.00016 21.7 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ27617.1 - 1.3e-26 93.6 0.0 1.9e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MULE PF10551.9 OAJ27618.1 - 1.2e-22 80.1 0.0 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ27618.1 - 5.3e-06 25.5 0.2 9.2e-05 21.5 0.0 2.2 2 0 0 2 2 2 1 Transposase, Mutator family FAR1 PF03101.15 OAJ27618.1 - 0.25 12.1 1.7 0.62 10.8 1.7 1.7 1 0 0 1 1 1 0 FAR1 DNA-binding domain NB-ARC PF00931.22 OAJ27619.1 - 3.1e-05 23.3 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 OAJ27619.1 - 0.0028 17.8 0.2 0.032 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 OAJ27619.1 - 0.004 16.9 0.0 0.0093 15.7 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 OAJ27619.1 - 0.0096 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 OAJ27619.1 - 0.023 13.9 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 OAJ27619.1 - 0.023 15.2 0.0 0.057 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAJ27619.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ27619.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ27619.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 OAJ27619.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 OAJ27619.1 - 0.19 12.2 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) COesterase PF00135.28 OAJ27620.1 - 1e-68 232.5 0.1 2.1e-60 205.1 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ27620.1 - 0.0028 17.5 0.2 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold KH_8 PF17903.1 OAJ27621.1 - 2.7e-31 107.5 0.0 5.4e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 OAJ27621.1 - 7.9e-05 22.4 0.2 0.00023 20.9 0.0 1.8 2 0 0 2 2 2 1 KH domain RhoGEF PF00621.20 OAJ27623.1 - 9.2e-38 130.3 0.0 1.4e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 OAJ27623.1 - 6.6e-08 32.2 0.4 0.0049 16.6 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ27623.1 - 8.3e-07 29.2 0.3 3.1e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) PH_17 PF18012.1 OAJ27623.1 - 0.0035 17.0 0.1 0.008 15.9 0.1 1.6 1 0 0 1 1 1 1 PH domain LRR_1 PF00560.33 OAJ27623.1 - 0.019 15.4 0.2 8.1 7.4 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 OAJ27623.1 - 0.36 11.0 2.2 28 5.1 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat HSF_DNA-bind PF00447.17 OAJ27624.1 - 2e-28 98.8 0.4 3.1e-28 98.2 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-B_dimeris PF09026.10 OAJ27624.1 - 1.6 9.2 9.8 3.4 8.1 9.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ27624.1 - 7.7 5.7 6.8 12 5.1 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Alpha-amylase_C PF02806.18 OAJ27625.1 - 6.7e-28 97.0 0.1 1.7e-27 95.7 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 OAJ27625.1 - 1.4e-16 61.0 0.0 5.9e-12 45.8 0.0 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 OAJ27625.1 - 4.2e-15 55.9 0.0 1.5e-14 54.1 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aminotran_1_2 PF00155.21 OAJ27625.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II PAT1 PF09770.9 OAJ27626.1 - 0.0032 15.8 40.1 0.0034 15.7 40.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 VIR_N PF15912.5 OAJ27626.1 - 0.24 11.0 17.6 0.37 10.3 17.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal RIFIN PF02009.16 OAJ27626.1 - 2.9 7.7 14.7 3.9 7.3 14.7 1.1 1 0 0 1 1 1 0 Rifin RR_TM4-6 PF06459.12 OAJ27626.1 - 3.1 7.5 24.7 4.5 7.0 24.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4661 PF15576.6 OAJ27626.1 - 8.5 6.2 11.5 13 5.6 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) MARVEL PF01284.23 OAJ27627.1 - 0.22 11.6 16.7 0.78 9.8 16.1 2.2 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.16 OAJ27628.1 - 6.2e-46 156.9 46.8 6.2e-46 156.9 46.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ27628.1 - 3.7e-10 38.9 6.8 6e-10 38.2 6.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Septin PF00735.18 OAJ27629.1 - 1.3e-121 405.2 0.1 2.5e-121 404.3 0.1 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 OAJ27629.1 - 5e-08 33.0 0.1 1.8e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ27629.1 - 9e-06 25.7 4.9 4e-05 23.6 0.1 2.8 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 OAJ27629.1 - 6.5e-05 22.5 2.9 0.00055 19.5 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 OAJ27629.1 - 0.00036 20.1 0.3 0.004 16.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 OAJ27629.1 - 0.002 18.4 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ27629.1 - 0.0021 18.5 0.1 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 OAJ27629.1 - 0.0022 17.3 1.4 0.0047 16.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 OAJ27629.1 - 0.0057 17.2 7.5 1.1 9.7 7.5 2.6 1 1 0 1 1 1 1 ABC transporter baeRF_family3 PF18845.1 OAJ27629.1 - 0.0069 16.7 2.8 0.015 15.6 2.8 1.6 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 3 Dynamin_N PF00350.23 OAJ27629.1 - 0.0099 16.0 6.9 0.082 13.0 0.0 3.4 2 2 0 3 3 3 1 Dynamin family Roc PF08477.13 OAJ27629.1 - 0.01 16.0 0.0 0.033 14.4 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ27629.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAJ27629.1 - 0.036 14.4 0.1 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAJ27629.1 - 0.048 12.8 1.3 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 OAJ27629.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 OAJ27629.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 OAJ27629.1 - 0.53 10.7 10.8 57 4.1 10.8 2.2 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 OAJ27629.1 - 0.73 9.3 7.0 1.2 8.6 7.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATP_bind_1 PF03029.17 OAJ27629.1 - 1.7 8.4 5.3 24 4.6 0.0 3.5 3 2 0 3 3 3 0 Conserved hypothetical ATP binding protein Strep_SA_rep PF06696.11 OAJ27629.1 - 5.7 7.1 9.5 0.48 10.5 0.6 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Dimer_Tnp_hAT PF05699.14 OAJ27630.1 - 1.4e-08 34.4 0.1 6.1e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region RTC_insert PF05189.13 OAJ27630.1 - 0.058 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain Vps26 PF03643.15 OAJ27631.1 - 6.1e-130 432.2 3.6 7e-130 432.0 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DUF4097 PF13349.6 OAJ27633.1 - 4.9e-05 22.8 1.3 0.00012 21.5 1.3 1.6 1 1 0 1 1 1 1 Putative adhesin PBP_N PF17093.5 OAJ27633.1 - 0.012 15.9 0.6 0.012 15.9 0.6 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Aminotran_5 PF00266.19 OAJ27634.1 - 1.3e-29 103.3 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 OAJ27634.1 - 0.0033 17.4 0.0 0.0096 15.9 0.0 1.8 1 1 0 1 1 1 1 B12 binding domain Tropomyosin_1 PF12718.7 OAJ27635.1 - 3.3e-47 160.2 29.7 4e-47 160.0 29.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 OAJ27635.1 - 2.1e-11 43.7 30.6 3e-06 26.8 11.0 2.4 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.9 OAJ27635.1 - 0.00027 21.0 31.0 0.0017 18.4 8.5 3.3 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KELK PF15796.5 OAJ27635.1 - 0.00089 19.7 2.9 0.00089 19.7 2.9 3.7 2 2 1 3 3 3 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase HrpB7 PF09486.10 OAJ27635.1 - 0.0014 19.0 20.1 0.011 16.1 6.3 2.3 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB7) BRE1 PF08647.11 OAJ27635.1 - 0.0021 18.1 12.7 0.0021 18.1 12.7 2.5 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase DHR10 PF18595.1 OAJ27635.1 - 0.0029 17.7 30.0 0.019 15.0 12.9 2.6 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 OAJ27635.1 - 0.0031 16.5 29.1 0.12 11.3 10.7 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein Uso1_p115_C PF04871.13 OAJ27635.1 - 0.0035 17.7 32.1 0.005 17.2 13.5 2.1 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region RasGAP_C PF03836.15 OAJ27635.1 - 0.0041 17.3 5.3 0.0041 17.3 5.3 2.0 1 1 1 2 2 2 1 RasGAP C-terminus Fez1 PF06818.15 OAJ27635.1 - 0.0053 17.2 23.0 0.0053 17.2 23.0 1.5 1 1 0 1 1 1 1 Fez1 GAS PF13851.6 OAJ27635.1 - 0.0075 15.6 25.6 0.068 12.5 7.2 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ERM PF00769.19 OAJ27635.1 - 0.0086 15.9 33.6 0.44 10.3 15.8 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family FliD_C PF07195.12 OAJ27635.1 - 0.0097 15.4 11.7 0.02 14.3 3.9 2.5 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus ADIP PF11559.8 OAJ27635.1 - 0.012 15.7 26.8 0.61 10.2 7.0 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 OAJ27635.1 - 0.016 14.6 23.1 0.17 11.2 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 OAJ27635.1 - 0.02 14.9 33.8 0.25 11.4 7.8 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4763 PF15960.5 OAJ27635.1 - 0.021 14.2 12.5 0.16 11.2 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) GIT_CC PF16559.5 OAJ27635.1 - 0.039 13.8 1.6 0.039 13.8 1.6 2.6 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 OAJ27635.1 - 0.039 14.0 14.2 0.071 13.1 2.3 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) CASP_C PF08172.12 OAJ27635.1 - 0.04 13.3 20.5 0.31 10.3 14.9 2.0 1 1 1 2 2 2 0 CASP C terminal Csm1_N PF18504.1 OAJ27635.1 - 0.041 14.2 5.3 0.041 14.2 5.3 3.5 2 2 2 4 4 4 0 Csm1 N-terminal domain DUF4200 PF13863.6 OAJ27635.1 - 0.047 14.1 28.6 0.27 11.7 8.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 OAJ27635.1 - 0.065 12.7 25.4 0.085 12.3 25.4 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal XhlA PF10779.9 OAJ27635.1 - 0.086 13.1 22.5 0.21 11.8 5.3 3.9 1 1 2 3 3 3 0 Haemolysin XhlA EzrA PF06160.12 OAJ27635.1 - 0.093 10.9 22.3 0.017 13.3 9.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 OAJ27635.1 - 0.11 13.0 35.2 2.2 8.8 13.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 OAJ27635.1 - 0.12 12.7 16.0 1.1 9.6 2.1 3.0 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 OAJ27635.1 - 0.16 11.7 25.9 0.75 9.6 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Filament PF00038.21 OAJ27635.1 - 0.17 11.5 25.9 0.43 10.1 11.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF919 PF06034.11 OAJ27635.1 - 0.2 11.5 7.4 0.16 11.8 0.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF5082 PF16888.5 OAJ27635.1 - 0.21 11.9 17.6 1.3 9.3 4.7 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) T3SSipB PF16535.5 OAJ27635.1 - 0.29 11.6 17.9 2.5 8.5 17.5 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB Lebercilin PF15619.6 OAJ27635.1 - 0.37 10.4 30.0 1.6 8.4 13.4 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 OAJ27635.1 - 0.39 8.2 24.7 0.45 8.0 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 OAJ27635.1 - 0.39 10.9 14.3 0.72 10.0 4.1 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF4927 PF16279.5 OAJ27635.1 - 0.41 11.7 12.5 0.067 14.2 3.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4927) Jnk-SapK_ap_N PF09744.9 OAJ27635.1 - 0.42 10.8 31.7 0.48 10.6 10.1 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Dynamitin PF04912.14 OAJ27635.1 - 0.46 9.7 22.7 0.13 11.6 17.4 2.3 1 1 1 2 2 2 0 Dynamitin Prefoldin_2 PF01920.20 OAJ27635.1 - 0.53 10.3 26.1 2.6 8.0 4.8 3.7 1 1 1 3 3 3 0 Prefoldin subunit DUF2730 PF10805.8 OAJ27635.1 - 0.54 10.4 10.2 0.23 11.6 2.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) KLRAQ PF10205.9 OAJ27635.1 - 0.69 10.2 18.5 0.43 10.9 6.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 OAJ27635.1 - 0.7 8.9 22.6 0.27 10.3 14.3 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 OAJ27635.1 - 0.84 9.8 29.7 2.6 8.2 11.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 OAJ27635.1 - 0.84 10.3 15.3 0.28 11.8 3.1 3.3 1 1 3 4 4 4 0 SlyX Golgin_A5 PF09787.9 OAJ27635.1 - 1.1 8.7 26.1 5.1 6.5 26.1 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 IFT57 PF10498.9 OAJ27635.1 - 1.2 8.0 19.2 0.69 8.8 3.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.8 OAJ27635.1 - 1.3 9.1 33.8 0.45 10.5 11.7 3.7 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 OAJ27635.1 - 1.5 9.2 22.4 0.045 14.1 5.4 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 OAJ27635.1 - 1.5 9.2 23.5 1.8 9.0 2.5 3.6 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF812 PF05667.11 OAJ27635.1 - 1.6 7.5 26.1 3.4 6.5 26.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 OAJ27635.1 - 1.7 7.9 20.3 2.7 7.3 20.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 OAJ27635.1 - 1.9 8.5 5.5 0.65 10.0 1.9 2.1 2 0 0 2 2 2 0 Sec20 Sec34 PF04136.15 OAJ27635.1 - 1.9 8.3 13.5 0.29 11.0 2.7 2.3 1 1 1 2 2 2 0 Sec34-like family V_ATPase_I PF01496.19 OAJ27635.1 - 2.1 6.2 15.9 1.9 6.3 14.9 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF5320 PF17253.2 OAJ27635.1 - 2.1 9.4 16.4 1.1 10.4 1.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5320) TRAF_BIRC3_bd PF16673.5 OAJ27635.1 - 2.2 8.2 15.6 0.51 10.2 4.4 3.3 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF2203 PF09969.9 OAJ27635.1 - 2.2 9.0 18.6 1 10.1 4.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) CorA PF01544.18 OAJ27635.1 - 2.4 7.4 6.6 3.5 6.8 6.5 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.12 OAJ27635.1 - 2.5 8.1 16.3 2.7 8.0 5.0 2.6 1 1 0 2 2 2 0 Laminin Domain II YscO PF07321.12 OAJ27635.1 - 2.7 8.0 31.2 3.1 7.7 12.6 2.7 1 1 1 2 2 2 0 Type III secretion protein YscO Allexi_40kDa PF05549.11 OAJ27635.1 - 3.3 7.2 13.0 4.1 6.8 6.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF16 PF01519.16 OAJ27635.1 - 3.3 8.3 15.0 1.2 9.7 2.9 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 DUF730 PF05325.11 OAJ27635.1 - 3.3 7.8 11.6 2.3 8.2 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF730) KASH_CCD PF14662.6 OAJ27635.1 - 3.4 7.5 27.3 0.71 9.7 9.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 OAJ27635.1 - 3.5 8.0 18.1 0.69 10.3 3.4 2.4 2 1 0 2 2 2 0 Tup N-terminal DUF4472 PF14739.6 OAJ27635.1 - 5 7.9 24.0 10 6.9 9.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) LPP PF04728.13 OAJ27635.1 - 5.3 7.5 9.7 1.6 9.2 0.1 3.7 2 2 1 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 OAJ27635.1 - 6 7.3 18.5 5.6 7.4 1.5 4.4 1 1 5 6 6 6 0 Flagella accessory protein C (FlaC) GTP-bdg_M PF16360.5 OAJ27635.1 - 6.1 7.5 14.8 0.19 12.3 2.3 3.3 2 2 1 3 3 3 0 GTP-binding GTPase Middle Region KxDL PF10241.9 OAJ27635.1 - 6.8 7.0 15.9 0.49 10.7 2.8 3.4 1 1 3 4 4 4 0 Uncharacterized conserved protein HemX PF04375.14 OAJ27635.1 - 6.9 5.9 19.4 2 7.6 6.7 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Prominin PF05478.11 OAJ27635.1 - 7.8 4.3 8.7 8.8 4.1 8.7 1.1 1 0 0 1 1 1 0 Prominin HAUS-augmin3 PF14932.6 OAJ27635.1 - 8 6.0 26.1 1.1 8.7 13.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3446 PF11928.8 OAJ27636.1 - 0.33 11.3 5.4 0.96 9.8 5.4 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF4097 PF13349.6 OAJ27638.1 - 0.00028 20.3 0.2 0.0046 16.3 0.1 2.5 2 1 0 2 2 2 1 Putative adhesin PBP1_TM PF14812.6 OAJ27638.1 - 1.9 8.9 15.6 7.7 7.0 0.9 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_3 PF13358.6 OAJ27639.1 - 3.8e-11 42.9 0.2 5.7e-11 42.4 0.2 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF423 PF04241.15 OAJ27640.1 - 1.6e-24 85.9 2.8 2.5e-24 85.3 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF2627 PF11118.8 OAJ27640.1 - 0.13 12.8 0.8 1.5 9.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Glyco_transf_28 PF03033.20 OAJ27641.1 - 2.4e-32 111.9 0.0 5.8e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ27641.1 - 3.6e-09 36.5 0.1 0.0024 17.7 0.0 3.6 4 0 0 4 4 4 2 GRAM domain UDPGT PF00201.18 OAJ27641.1 - 0.00067 18.6 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 OAJ27641.1 - 0.19 12.2 0.0 0.56 10.7 0.0 1.8 1 0 0 1 1 1 0 PH domain Antimicrobial10 PF08105.11 OAJ27642.1 - 1.1 9.4 4.5 0.28 11.3 0.8 2.0 2 1 0 2 2 2 0 Metchnikowin family CENP-T_C PF15511.6 OAJ27644.1 - 9.1e-09 35.4 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ27644.1 - 0.00041 20.5 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ27644.1 - 0.0015 18.8 0.1 0.0023 18.3 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PCP_red PF08369.10 OAJ27644.1 - 0.027 14.7 0.4 3.2 8.1 0.1 2.6 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Histone PF00125.24 OAJ27644.1 - 0.044 14.1 0.1 0.046 14.1 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 OAJ27644.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 OAJ27644.1 - 0.11 12.8 0.1 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_S49 PF01343.18 OAJ27646.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 NuDC PF16273.5 OAJ27646.1 - 6.8 7.3 9.5 6.1 7.4 0.0 3.3 3 0 0 3 3 3 0 Nuclear distribution C domain Apolipoprotein PF01442.18 OAJ27648.1 - 0.00018 21.4 9.8 0.00025 21.0 9.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Cast PF10174.9 OAJ27648.1 - 0.001 17.4 2.0 0.0013 17.1 2.0 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF842 PF05811.13 OAJ27648.1 - 0.0035 17.0 2.3 0.0058 16.3 2.3 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1664 PF07889.12 OAJ27648.1 - 0.0035 17.4 6.9 0.14 12.2 5.3 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 OAJ27648.1 - 0.0069 16.0 2.8 0.0087 15.7 2.8 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit ApoLp-III PF07464.11 OAJ27648.1 - 0.025 14.7 0.7 0.025 14.7 0.7 2.3 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) BORCS6 PF10157.9 OAJ27648.1 - 0.054 13.7 1.8 0.11 12.8 1.8 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 V-ATPase_G_2 PF16999.5 OAJ27648.1 - 0.069 13.6 3.3 0.11 12.9 1.8 2.0 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Prominin PF05478.11 OAJ27648.1 - 0.075 11.0 2.0 0.082 10.9 2.0 1.1 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.12 OAJ27648.1 - 0.091 12.8 6.1 0.74 9.9 5.3 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 OAJ27648.1 - 0.15 12.1 6.9 0.74 9.8 1.9 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fzo_mitofusin PF04799.13 OAJ27648.1 - 0.17 11.4 8.3 0.38 10.3 6.8 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 OAJ27648.1 - 2.3 8.9 6.6 3.4 8.3 4.2 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) AKNA PF12443.8 OAJ27648.1 - 3.3 8.4 9.3 4.3 8.0 2.3 3.0 2 1 2 4 4 3 0 AT-hook-containing transcription factor CxC4 PF18717.1 OAJ27649.1 - 0.00043 20.1 0.5 0.0012 18.6 0.5 1.8 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases Homeobox_KN PF05920.11 OAJ27650.1 - 1e-10 41.3 0.0 3e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Homeobox KN domain Ribonucleas_3_3 PF14622.6 OAJ27651.1 - 7.9e-21 74.6 0.1 1.6e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Spt20 PF12090.8 OAJ27651.1 - 0.012 15.2 12.0 0.017 14.7 12.0 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ27651.1 - 0.021 14.9 11.6 0.027 14.5 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 OAJ27651.1 - 0.39 10.6 8.7 0.45 10.4 8.7 1.2 1 0 0 1 1 1 0 SPX domain Zip PF02535.22 OAJ27651.1 - 1.1 8.4 8.3 1.7 7.8 8.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.13 OAJ27651.1 - 1.4 9.6 17.8 3 8.5 17.8 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4551 PF15087.6 OAJ27651.1 - 1.8 7.3 9.2 2.7 6.7 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 OAJ27651.1 - 2.6 6.1 4.6 3.2 5.8 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 OAJ27651.1 - 2.7 6.2 16.3 3.4 5.8 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 OAJ27651.1 - 9.7 6.1 9.8 15 5.5 9.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DAO PF01266.24 OAJ27652.1 - 4.4e-33 115.3 0.8 1.7e-32 113.4 0.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ27652.1 - 0.00033 20.8 0.0 0.0013 18.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ27652.1 - 0.034 13.4 0.0 0.56 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 OAJ27652.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Mqo PF06039.15 OAJ27652.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FHA PF00498.26 OAJ27653.1 - 1e-14 54.6 0.0 2.4e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ27653.1 - 0.0033 17.7 0.0 0.0092 16.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Catalase PF00199.19 OAJ27654.1 - 1.8e-168 560.6 0.1 2.3e-168 560.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ27654.1 - 4.4e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive ATP13 PF12921.7 OAJ27655.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase expression DUF5407 PF17401.2 OAJ27655.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) Ribosomal_L44 PF00935.19 OAJ27657.1 - 4.8e-36 123.1 12.7 7.1e-36 122.5 12.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L14e PF01929.17 OAJ27658.1 - 3.1e-27 94.9 0.7 4.7e-27 94.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 OAJ27658.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 KOW motif DUF1768 PF08719.11 OAJ27664.1 - 1e-24 87.6 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Pkinase PF00069.25 OAJ27665.1 - 1.9e-54 184.8 0.0 2.9e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27665.1 - 1.4e-41 142.5 0.0 2.2e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ27665.1 - 2.3e-06 26.7 2.2 2.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ27665.1 - 0.018 14.9 1.5 0.12 12.2 0.7 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ27665.1 - 0.1 11.9 0.0 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAJ27665.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SHD1 PF03983.12 OAJ27666.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 Med21 PF11221.8 OAJ27667.1 - 1.8e-21 76.9 2.0 2.3e-21 76.5 2.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DHHA2 PF02833.14 OAJ27668.1 - 1.5e-18 67.3 0.1 3.5e-18 66.2 0.1 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 OAJ27668.1 - 1.9e-10 40.8 0.0 1.5e-09 38.0 0.0 2.1 1 1 1 2 2 2 1 DHH family Sugar_tr PF00083.24 OAJ27669.1 - 1.4e-89 301.1 22.7 1.7e-89 300.8 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ27669.1 - 1.3e-13 50.6 41.8 8.4e-12 44.7 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4799 PF16056.5 OAJ27673.1 - 0.059 12.5 0.1 0.065 12.4 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) ERCC3_RAD25_C PF16203.5 OAJ27674.1 - 1.8e-122 407.3 0.0 3e-122 406.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 OAJ27674.1 - 2e-35 121.7 0.0 4.2e-35 120.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ27674.1 - 2.3e-16 60.3 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ27674.1 - 2e-10 41.0 0.1 4.8e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 OAJ27674.1 - 8.5e-08 31.3 0.0 1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 OAJ27674.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase CDC45 PF02724.14 OAJ27674.1 - 5.8 5.1 7.7 9.3 4.4 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.23 OAJ27675.1 - 3e-11 43.2 1.6 4.9e-11 42.5 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ27675.1 - 0.00042 20.3 0.4 0.001 19.0 0.4 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat SUIM_assoc PF16619.5 OAJ27675.1 - 0.086 12.9 3.6 0.32 11.1 3.6 2.0 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Cyclin_C_2 PF16899.5 OAJ27675.1 - 0.18 12.2 0.6 0.67 10.4 0.2 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain Helicase_C PF00271.31 OAJ27676.1 - 5.2e-14 52.5 0.0 4.1e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ27676.1 - 3.5e-10 39.9 0.0 1.9e-09 37.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ27676.1 - 9.1e-06 25.8 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 OAJ27678.1 - 1.3e-47 162.7 0.0 2.2e-47 162.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ27678.1 - 2.9e-15 57.0 0.0 6.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ27678.1 - 9.5e-11 41.8 0.0 1.8e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ27678.1 - 4.3e-08 33.6 0.0 1.2e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ27678.1 - 2.5e-05 24.7 0.1 0.22 11.9 0.1 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 OAJ27678.1 - 0.0013 18.7 0.0 0.0041 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 OAJ27678.1 - 0.0014 19.1 0.0 0.0033 17.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAJ27678.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 OAJ27678.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ27678.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 OAJ27678.1 - 0.098 11.9 0.1 0.37 10.0 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 OAJ27678.1 - 0.19 10.8 0.1 0.99 8.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SCP2 PF02036.17 OAJ27679.1 - 1.3e-15 57.7 0.1 2.2e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 SCP-2 sterol transfer family WD40 PF00400.32 OAJ27680.1 - 4.5e-08 33.6 14.2 0.00058 20.6 0.2 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27680.1 - 0.069 13.5 0.0 7.6 6.9 0.0 3.7 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 OAJ27680.1 - 0.081 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split Equine_IAV_S2 PF06502.11 OAJ27680.1 - 0.081 13.0 0.2 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein D123 PF07065.14 OAJ27681.1 - 2.5e-77 260.0 0.0 5.4e-77 259.0 0.0 1.6 1 1 0 1 1 1 1 D123 Pkinase PF00069.25 OAJ27682.1 - 4e-62 210.0 0.0 5.5e-60 203.0 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27682.1 - 1.5e-22 80.2 0.0 1.2e-20 73.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ27682.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IMUP PF15761.5 OAJ27682.1 - 0.0072 17.0 2.6 0.011 16.4 2.6 1.2 1 0 0 1 1 1 1 Immortalisation up-regulated protein APH PF01636.23 OAJ27682.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ27682.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FAM199X PF15814.5 OAJ27682.1 - 0.032 13.3 0.7 0.045 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X FTA2 PF13095.6 OAJ27682.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF1679 PF07914.11 OAJ27682.1 - 0.082 11.8 0.5 0.18 10.6 0.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) Kdo PF06293.14 OAJ27682.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3138 PF11336.8 OAJ27682.1 - 0.35 9.4 2.6 0.48 9.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Aminotran_1_2 PF00155.21 OAJ27683.1 - 3.6e-58 197.5 0.0 4.8e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ofd1_CTDD PF10637.9 OAJ27684.1 - 1.2e-81 273.8 0.4 7.9e-77 258.1 0.6 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 OAJ27684.1 - 6.2e-33 113.3 0.0 1.4e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 OAJ27684.1 - 1.9e-15 57.5 0.0 4.8e-15 56.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.12 OAJ27684.1 - 0.36 10.5 9.7 0.91 9.2 9.7 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 OAJ27684.1 - 4.6 5.3 13.2 8.3 4.5 13.2 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OAJ27684.1 - 6.5 6.6 10.7 14 5.5 10.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5635 PF18685.1 OAJ27685.1 - 0.1 12.5 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5635) rve PF00665.26 OAJ27686.1 - 1.1e-17 64.4 0.0 2.1e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ27686.1 - 4.8e-15 55.5 0.0 9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 OAJ27686.1 - 0.001 18.7 1.3 0.0013 18.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 OAJ27686.1 - 0.0034 17.2 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ27686.1 - 0.012 15.4 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain HTH_15 PF12324.8 OAJ27686.1 - 0.11 12.5 0.1 2.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase zf-CCHC PF00098.23 OAJ27686.1 - 1.1 9.5 3.4 2.4 8.4 3.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Keratin_2_head PF16208.5 OAJ27686.1 - 1.5 8.9 15.2 3.8 7.6 15.2 1.6 1 0 0 1 1 1 0 Keratin type II head Glypican PF01153.19 OAJ27687.1 - 0.47 9.2 1.5 0.64 8.8 1.5 1.1 1 0 0 1 1 1 0 Glypican CDC45 PF02724.14 OAJ27687.1 - 1.9 6.7 9.9 2.4 6.4 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RVT_2 PF07727.14 OAJ27688.1 - 3.9e-13 49.6 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ27688.1 - 0.0033 17.2 3.5 0.0065 16.3 3.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like dCMP_cyt_deam_1 PF00383.23 OAJ27690.1 - 1.1e-25 89.4 0.7 1.9e-25 88.7 0.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ27690.1 - 1.5e-09 37.8 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 OAJ27690.1 - 0.00023 21.7 0.0 0.00066 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ27690.1 - 0.0089 16.2 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain SNAD4 PF18750.1 OAJ27690.1 - 0.05 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 OAJ27690.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase TRAM_LAG1_CLN8 PF03798.16 OAJ27693.1 - 2.1e-34 119.0 24.4 2.1e-34 119.0 24.4 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 OAJ27693.1 - 2.5e-19 68.7 0.1 7.4e-19 67.2 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein HGTP_anticodon PF03129.20 OAJ27694.1 - 9.7e-21 73.7 0.4 3.8e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ27694.1 - 8.5e-09 35.6 0.0 1.8e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) InPase PF18823.1 OAJ27694.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase LtrA PF06772.11 OAJ27695.1 - 9.5e-35 120.4 23.8 1.3e-34 120.0 23.8 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4079 PF13301.6 OAJ27695.1 - 1.4 9.1 5.7 3.8 7.7 4.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) 4HBT_2 PF13279.6 OAJ27696.1 - 4.3e-18 66.0 0.0 6.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 OAJ27696.1 - 5.5e-05 22.6 0.3 0.0012 18.2 0.6 2.1 1 1 0 2 2 2 1 Acyl-ACP thioesterase 4HBT PF03061.22 OAJ27696.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.7 1 1 0 1 1 1 0 Thioesterase superfamily adh_short PF00106.25 OAJ27697.1 - 1.3e-28 99.8 0.0 1.7e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ27697.1 - 1e-18 67.8 0.0 1.5e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ27697.1 - 2.5e-05 24.3 0.4 9.2e-05 22.4 0.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ27697.1 - 0.0024 17.4 0.0 0.0055 16.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CAF1C_H4-bd PF12265.8 OAJ27698.1 - 3.5e-15 56.0 0.0 1.3e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ27698.1 - 1.6e-13 50.9 5.5 1.9e-06 28.5 0.2 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat GARS_A PF01071.19 OAJ27699.1 - 3.3e-67 226.1 0.0 4.8e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 OAJ27699.1 - 1.1e-29 103.0 0.1 4.4e-29 101.1 0.1 2.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 OAJ27699.1 - 1.4e-27 96.8 0.0 3.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 OAJ27699.1 - 1.1e-26 93.0 0.4 2.5e-26 91.8 0.4 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 OAJ27699.1 - 4.5e-13 49.7 1.1 2.4e-12 47.3 1.3 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Shikimate_DH PF01488.20 OAJ27699.1 - 0.15 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase WD40 PF00400.32 OAJ27700.1 - 1.6e-39 133.2 20.1 7.6e-07 29.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27700.1 - 1.5e-13 50.8 0.2 0.00078 19.7 0.1 4.6 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 OAJ27700.1 - 0.022 14.1 0.0 0.18 11.1 0.0 2.0 2 1 1 3 3 3 0 WD40-like domain zf-C2H2 PF00096.26 OAJ27701.1 - 2.7e-25 87.4 58.8 0.00068 20.0 1.9 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ27701.1 - 2.5e-15 55.8 58.2 0.0077 17.0 1.4 10.5 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ27701.1 - 2.7e-05 24.3 12.7 1.9 8.9 0.0 7.1 7 0 0 7 7 7 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 OAJ27701.1 - 2.7e-05 24.4 4.7 0.003 17.9 1.9 11.4 12 0 0 12 12 12 3 Zinc-finger double domain RNA_pol_3_Rpc31 PF11705.8 OAJ27701.1 - 0.00066 20.0 3.3 0.00066 20.0 3.3 4.7 4 1 0 4 4 3 1 DNA-directed RNA polymerase III subunit Rpc31 FOXP-CC PF16159.5 OAJ27701.1 - 0.0041 17.7 28.4 0.78 10.4 0.7 7.0 6 1 1 7 7 7 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 OAJ27701.1 - 0.31 11.4 21.8 1.8 8.9 1.7 6.1 3 2 3 6 6 6 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 OAJ27701.1 - 0.75 9.9 11.2 9.3 6.4 0.0 5.0 6 0 0 6 6 6 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 OAJ27701.1 - 0.9 9.7 4.6 29 4.8 0.1 4.6 4 1 1 5 5 5 0 Aberrant zinc-finger Ogr_Delta PF04606.12 OAJ27701.1 - 1.3 9.1 7.2 1.6 8.8 0.5 4.2 5 0 0 5 5 5 0 Ogr/Delta-like zinc finger AGH PF17558.2 OAJ27701.1 - 2.3 8.4 6.5 1.4 9.1 0.5 3.4 3 0 0 3 3 3 0 Androgenic gland hormone Ank_2 PF12796.7 OAJ27702.1 - 3.8e-11 43.4 0.2 3.2e-06 27.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ27702.1 - 6.5e-07 29.8 0.3 0.011 16.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ27702.1 - 0.0006 20.1 0.0 3.7 8.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ27702.1 - 0.0076 16.7 0.0 1.9 9.1 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 OAJ27702.1 - 0.013 16.0 0.2 74 4.4 0.0 4.9 5 1 0 5 5 5 0 Ankyrin repeat HA2 PF04408.23 OAJ27704.1 - 1.3e-14 54.3 0.1 1.3e-14 54.3 0.1 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ27704.1 - 1.8e-09 37.8 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ27704.1 - 1.7e-07 31.5 0.0 1.3e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OAJ27704.1 - 0.0025 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 OAJ27704.1 - 0.0038 17.5 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 OAJ27704.1 - 0.013 15.3 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 OAJ27704.1 - 0.093 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family PhoH PF02562.16 OAJ27704.1 - 0.19 11.1 0.2 0.88 9.0 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein FAM176 PF14851.6 OAJ27704.1 - 3.8 7.2 10.8 29 4.3 0.0 4.0 4 0 0 4 4 4 0 FAM176 family DUF1741 PF08427.10 OAJ27705.1 - 0.00015 21.5 4.7 0.022 14.4 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF1741) Hydrolase_4 PF12146.8 OAJ27707.1 - 0.00032 20.0 0.1 0.4 9.9 0.1 2.7 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ27707.1 - 0.0034 17.1 0.1 0.0034 17.1 0.1 3.2 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ27707.1 - 0.097 12.8 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein GRIM-19 PF06212.12 OAJ27708.1 - 1.3e-31 109.3 0.0 1.5e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein CDP-OH_P_transf PF01066.21 OAJ27709.1 - 1.3e-12 48.2 0.8 1.3e-12 48.2 0.8 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GMC_oxred_C PF05199.13 OAJ27710.1 - 7.1e-11 42.8 0.0 7.8e-11 42.7 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase ICE2 PF08426.10 OAJ27710.1 - 0.091 11.9 0.0 0.096 11.8 0.0 1.0 1 0 0 1 1 1 0 ICE2 R3H PF01424.22 OAJ27711.1 - 8.8e-11 41.6 0.2 1.9e-10 40.6 0.2 1.6 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 OAJ27711.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAC PF01849.18 OAJ27712.1 - 1.7e-20 72.7 0.0 4.5e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 NAC domain Striatin PF08232.12 OAJ27713.1 - 1.3e-46 159.0 2.4 1.3e-46 159.0 2.4 5.0 3 2 0 3 3 3 1 Striatin family Macoilin PF09726.9 OAJ27713.1 - 3 6.3 10.2 0.48 8.9 1.8 2.2 2 0 0 2 2 2 0 Macoilin family DAGAT PF03982.13 OAJ27715.1 - 2.7e-94 315.4 0.0 1.6e-49 168.5 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Glyco_trans_2_3 PF13632.6 OAJ27715.1 - 0.083 12.8 1.0 2.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Glycosyl transferase family group 2 Urm1 PF09138.11 OAJ27716.1 - 3.9e-32 110.5 0.0 5.9e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) His_Phos_1 PF00300.22 OAJ27716.1 - 5.9e-30 104.4 1.7 5.3e-28 98.0 1.7 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThiS PF02597.20 OAJ27716.1 - 0.022 15.4 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 ThiS family LRR_8 PF13855.6 OAJ27717.1 - 7.5e-11 41.6 2.4 1.4e-10 40.7 2.4 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 OAJ27717.1 - 2.7e-08 34.0 2.7 1.7e-06 28.2 0.2 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ27717.1 - 0.00085 19.5 2.2 8.6 7.3 0.2 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat Pkinase PF00069.25 OAJ27718.1 - 1.5e-28 99.9 0.0 6.1e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27718.1 - 1.9e-13 50.3 0.0 1.2e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ27718.1 - 0.029 13.7 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RVT_3 PF13456.6 OAJ27719.1 - 0.0023 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ27719.1 - 0.0083 15.5 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain RVT_1 PF00078.27 OAJ27719.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ27719.1 - 0.13 12.3 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase COesterase PF00135.28 OAJ27720.1 - 6e-34 117.8 0.1 6.9e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ27720.1 - 1.4e-06 28.4 0.1 3.5e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ27720.1 - 0.004 17.8 0.2 0.0055 17.3 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ27720.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Phage_integrase PF00589.22 OAJ27721.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family ATP_bind_1 PF03029.17 OAJ27722.1 - 3.6e-74 249.6 0.0 4.4e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ27722.1 - 0.00012 22.0 0.0 0.00033 20.5 0.0 1.9 1 1 1 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 OAJ27722.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 OAJ27722.1 - 0.0085 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CBP_BcsQ PF06564.12 OAJ27722.1 - 0.014 14.9 0.0 22 4.4 0.0 3.2 2 1 0 3 3 3 0 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 OAJ27722.1 - 0.02 15.3 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 OAJ27722.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ27722.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 OAJ27722.1 - 0.049 13.8 0.0 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 OAJ27722.1 - 0.058 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 OAJ27722.1 - 0.088 13.1 0.0 0.3 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ27722.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain STE PF02200.16 OAJ27725.1 - 1.7e-35 121.8 0.0 2.7e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor WD40 PF00400.32 OAJ27726.1 - 8.2e-25 86.6 11.3 9e-05 23.2 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27726.1 - 0.0033 17.7 0.0 10 6.5 0.0 4.3 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BAF1_ABF1 PF04684.13 OAJ27726.1 - 1.1 8.3 7.2 0.15 11.1 1.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor RAP1 PF07218.11 OAJ27726.1 - 7.1 4.8 4.6 14 3.8 4.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_1 PF00561.20 OAJ27727.1 - 6.5e-26 91.5 0.2 7.7e-22 78.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ27727.1 - 1.5e-11 44.3 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAJ27727.1 - 0.022 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_8 PF01270.17 OAJ27728.1 - 4.7e-16 58.5 0.2 1.1e-15 57.4 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 8 Peptidase_S29 PF02907.15 OAJ27728.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease GTP_EFTU PF00009.27 OAJ27730.1 - 4.2e-42 143.9 0.0 6.9e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 OAJ27730.1 - 2.5e-33 115.3 7.1 4.1e-33 114.6 7.1 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 OAJ27730.1 - 7.8e-24 83.8 0.0 2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ27730.1 - 2.4e-20 72.3 0.0 6.1e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ27730.1 - 3.5e-07 30.5 0.1 7.4e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ27730.1 - 1.9e-06 27.9 0.1 3.6e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 OAJ27730.1 - 0.00015 21.8 0.1 0.00031 20.8 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 OAJ27730.1 - 0.00089 18.9 0.0 0.0026 17.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 OAJ27730.1 - 0.078 13.2 0.0 0.33 11.2 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ27730.1 - 0.11 11.9 0.2 0.34 10.3 0.0 1.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Spo7 PF03907.13 OAJ27731.1 - 2.8e-17 62.9 0.2 6.5e-08 32.3 0.1 2.3 2 0 0 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.9 OAJ27731.1 - 0.065 13.6 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 188 MARVEL PF01284.23 OAJ27731.1 - 0.67 10.0 8.2 0.21 11.6 0.8 2.6 3 0 0 3 3 3 0 Membrane-associating domain MPP6 PF10175.9 OAJ27732.1 - 0.0085 16.6 11.6 1.8 9.1 11.6 2.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 DEC-1_N PF04625.13 OAJ27732.1 - 0.32 10.0 4.8 0.51 9.3 4.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Hamartin PF04388.12 OAJ27732.1 - 1.2 7.8 5.7 1.4 7.5 5.7 1.0 1 0 0 1 1 1 0 Hamartin protein API5 PF05918.11 OAJ27732.1 - 6.5 5.4 5.1 10 4.8 5.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PBP1_TM PF14812.6 OAJ27732.1 - 9.6 6.7 18.5 5.3 7.5 3.3 2.4 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Serglycin PF04360.12 OAJ27733.1 - 0.061 13.3 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Serglycin PSK_trans_fac PF07704.11 OAJ27733.1 - 3.5 8.4 7.3 0.7 10.7 0.3 3.0 3 1 0 3 3 3 0 Rv0623-like transcription factor OPT PF03169.15 OAJ27735.1 - 3.9e-136 455.2 33.6 4e-135 451.9 33.6 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Spt5_N PF11942.8 OAJ27737.1 - 1.8e-19 70.5 10.8 1.8e-19 70.5 10.8 3.6 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 OAJ27737.1 - 7.1e-19 67.5 0.1 2e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 OAJ27737.1 - 2.3e-10 40.0 19.9 0.00069 19.5 0.1 5.0 5 0 0 5 5 5 4 KOW motif DUF4537 PF15057.6 OAJ27737.1 - 0.014 15.4 1.3 26 4.9 0.4 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4537) RNase_P_p30 PF01876.16 OAJ27737.1 - 0.15 11.5 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit p30 Utp14 PF04615.13 OAJ27737.1 - 0.92 8.0 25.0 1.3 7.5 25.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2457 PF10446.9 OAJ27737.1 - 4.1 6.4 34.9 7.1 5.7 34.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FHA PF00498.26 OAJ27738.1 - 0.00026 21.3 0.0 0.00076 19.8 0.0 1.8 1 0 0 1 1 1 1 FHA domain ORC6 PF05460.13 OAJ27738.1 - 0.13 11.5 9.7 0.19 11.0 9.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) GFO_IDH_MocA_C PF02894.17 OAJ27738.1 - 0.2 11.6 0.4 2.3 8.3 0.2 2.1 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain Zn_clus PF00172.18 OAJ27739.1 - 1.7e-05 24.8 10.2 2.6e-05 24.2 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 OAJ27740.1 - 2e-20 73.5 0.0 2.6e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 OAJ27740.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 OAJ27740.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase PE-PPE PF08237.11 OAJ27740.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.22 OAJ27741.1 - 1.7e-23 83.5 0.0 4.5e-23 82.1 0.0 1.6 1 1 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAJ27741.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 OAJ27741.1 - 0.007 16.0 0.0 0.011 15.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.11 OAJ27741.1 - 0.056 13.0 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF676 PF05057.14 OAJ27741.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_8 PF06259.12 OAJ27741.1 - 0.09 12.4 0.0 0.31 10.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase DUF3684 PF12449.8 OAJ27743.1 - 5.6e-294 978.1 0.2 1.2e-276 920.7 0.0 4.1 2 2 0 2 2 2 2 Protein of unknown function (DUF3684) DUF4112 PF13430.6 OAJ27744.1 - 2.4e-31 108.1 0.1 3.2e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3983 PF13137.6 OAJ27744.1 - 0.19 11.6 2.0 7.7 6.4 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3983) Sec16_C PF12931.7 OAJ27745.1 - 4.1e-92 309.1 0.0 5.8e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 OAJ27745.1 - 1.9e-19 70.4 0.1 6.9e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Tyr_Deacylase PF02580.16 OAJ27746.1 - 2.5e-52 177.3 0.0 3e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase E1-E2_ATPase PF00122.20 OAJ27747.1 - 7.6e-39 133.1 13.8 4.1e-30 104.7 0.0 3.5 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ27747.1 - 3.1e-30 105.2 2.8 3.1e-30 105.2 2.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ27747.1 - 2.2e-21 77.1 0.0 1.3e-19 71.3 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ27747.1 - 5.2e-20 71.3 0.1 1.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ27747.1 - 8.3e-15 54.2 0.0 8.3e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ27747.1 - 1.7e-07 31.3 0.1 9.2e-06 25.6 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP19 PF01922.17 OAJ27747.1 - 0.073 14.0 0.0 0.75 10.8 0.0 2.5 2 0 0 2 2 2 0 SRP19 protein Pkinase PF00069.25 OAJ27748.1 - 2.2e-40 138.7 0.0 8.5e-27 94.2 0.0 4.2 3 2 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27748.1 - 3.1e-23 82.4 0.0 1.2e-19 70.6 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ27748.1 - 0.0013 18.7 0.0 0.17 11.8 0.0 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ27748.1 - 0.036 13.4 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 OAJ27748.1 - 0.089 11.5 0.0 0.21 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase PBP1_TM PF14812.6 OAJ27748.1 - 3.2 8.2 15.4 19 5.7 4.9 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dynamin_N PF00350.23 OAJ27749.1 - 4e-17 62.8 0.0 1e-16 61.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAJ27749.1 - 4.6e-12 46.0 0.0 1.6e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ27749.1 - 4.3e-08 32.9 0.3 2.3e-05 24.0 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 OAJ27749.1 - 0.00076 19.4 1.4 0.88 9.4 0.1 3.0 2 1 0 2 2 2 2 RsgA GTPase IIGP PF05049.13 OAJ27749.1 - 0.0042 16.2 0.2 0.017 14.2 0.0 1.9 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) cobW PF02492.19 OAJ27749.1 - 0.012 15.2 0.1 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 OAJ27749.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 OAJ27749.1 - 0.031 14.5 0.2 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ27749.1 - 0.043 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_MLP1_2 PF07926.12 OAJ27749.1 - 0.045 13.8 6.9 0.03 14.4 3.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FeoB_N PF02421.18 OAJ27749.1 - 0.1 12.1 0.2 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B NPV_P10 PF05531.12 OAJ27749.1 - 0.19 12.2 6.3 26 5.4 0.1 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA_16 PF13191.6 OAJ27749.1 - 0.97 9.8 4.4 0.87 9.9 0.0 2.9 2 2 0 2 2 2 0 AAA ATPase domain Proteasome PF00227.26 OAJ27750.1 - 6.3e-38 130.2 0.0 7.1e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.18 OAJ27751.1 - 4.7e-06 26.6 9.9 9.8e-06 25.6 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ27751.1 - 1.2e-05 24.5 0.0 3.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDT1_C PF16679.5 OAJ27751.1 - 0.15 12.5 6.8 1.3 9.5 0.1 4.4 4 0 0 4 4 4 0 DNA replication factor Cdt1 C-terminal domain DUF1932 PF09130.11 OAJ27751.1 - 0.17 11.9 1.4 0.45 10.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1932) Sugarporin_N PF11471.8 OAJ27751.1 - 0.39 10.7 4.6 2.5 8.1 4.6 2.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DNA_ligase_OB_2 PF14743.6 OAJ27752.1 - 1.3e-28 98.8 0.3 4.8e-28 97.0 0.3 1.9 2 0 0 2 2 2 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 OAJ27752.1 - 1.7e-06 27.8 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Gastrin PF00918.17 OAJ27753.1 - 0.071 14.1 6.0 0.086 13.8 6.0 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family TraV PF09676.10 OAJ27753.1 - 4.8 8.2 12.2 7 7.6 12.2 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Methyltransf_11 PF08241.12 OAJ27754.1 - 1.2e-10 41.9 0.0 1.2e-09 38.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ27754.1 - 1.4e-10 41.7 0.0 3.2e-08 34.2 0.0 3.3 2 2 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ27754.1 - 1.8e-06 28.6 0.0 0.00011 22.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ27754.1 - 0.0065 16.3 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Phage_int_SAM_1 PF02899.17 OAJ27754.1 - 0.1 12.9 0.4 0.29 11.4 0.0 1.9 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ELFV_dehydrog PF00208.21 OAJ27755.1 - 7.6e-51 173.2 0.0 1.1e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 OAJ27755.1 - 2.1e-19 68.7 0.0 7.1e-14 50.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase UQ_con PF00179.26 OAJ27756.1 - 2.4e-41 140.6 0.0 3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 OAJ27756.1 - 2.8e-21 75.0 0.1 4.2e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 OAJ27756.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain DUF1421 PF07223.11 OAJ27756.1 - 0.0031 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain (DUF1421) UBA PF00627.31 OAJ27756.1 - 0.19 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Sporozoite_P67 PF05642.11 OAJ27756.1 - 0.62 8.1 6.4 0.8 7.7 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Meth_synt_2 PF01717.18 OAJ27757.1 - 4.9e-150 499.2 0.0 1.6e-143 477.9 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 OAJ27757.1 - 2.9e-116 388.4 0.0 2.7e-110 368.8 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain TPR_MLP1_2 PF07926.12 OAJ27757.1 - 0.42 10.7 2.6 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Exo70 PF03081.15 OAJ27758.1 - 3.1e-52 177.9 0.0 1.2e-51 175.9 0.0 1.8 1 1 0 1 1 1 1 Exo70 exocyst complex subunit Vps52 PF04129.12 OAJ27758.1 - 0.013 14.2 0.1 0.16 10.7 0.0 2.4 3 0 0 3 3 3 0 Vps52 / Sac2 family Baculo_PEP_C PF04513.12 OAJ27758.1 - 0.046 13.8 0.2 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 OAJ27758.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Sec34-like family FmiP_Thoc5 PF09766.9 OAJ27758.1 - 0.24 10.6 0.1 0.39 10.0 0.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RNase_H PF00075.24 OAJ27761.1 - 4.9e-33 114.3 0.0 6.3e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 OAJ27761.1 - 1.6e-20 73.1 0.2 2.8e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin TPR_10 PF13374.6 OAJ27762.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat YL1 PF05764.13 OAJ27763.1 - 0.011 15.8 9.8 0.011 15.8 9.8 2.0 2 1 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 OAJ27763.1 - 1.8 6.8 12.9 4.4 5.5 12.9 1.6 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 OAJ27763.1 - 2.6 6.8 4.5 4.3 6.1 4.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP-synt_DE PF00401.20 OAJ27764.1 - 0.12 12.7 3.8 0.2 12.0 3.8 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Cellulase PF00150.18 OAJ27765.1 - 4.5e-10 39.4 2.1 9.2e-10 38.4 2.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Serglycin PF04360.12 OAJ27765.1 - 0.018 15.0 0.6 0.018 15.0 0.6 2.6 2 0 0 2 2 2 0 Serglycin DUF5337 PF17272.2 OAJ27765.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Spc7 PF08317.11 OAJ27766.1 - 1.2 8.0 17.1 2.3 7.1 17.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Whi5 PF08528.11 OAJ27767.1 - 3e-09 36.3 0.0 4.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Whi5 like PGP_phosphatase PF09419.10 OAJ27768.1 - 7.8e-39 133.0 0.0 1.5e-34 119.1 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase FAD_binding_3 PF01494.19 OAJ27768.1 - 1.3e-15 57.5 4.1 1.5e-06 27.7 0.3 3.3 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.12 OAJ27768.1 - 0.00014 21.0 0.1 0.28 10.2 0.0 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 OAJ27768.1 - 0.0016 18.1 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ27768.1 - 0.0016 18.6 0.3 0.049 13.9 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Hydrolase_like PF13242.6 OAJ27768.1 - 0.053 13.6 0.1 0.78 9.8 0.0 2.7 2 0 0 2 2 2 0 HAD-hyrolase-like Pyr_redox PF00070.27 OAJ27768.1 - 0.083 13.5 0.1 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAJ27768.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 OAJ27768.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3915 PF13054.6 OAJ27769.1 - 0.026 14.5 6.4 0.038 14.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) eIF3_subunit PF08597.10 OAJ27769.1 - 0.076 12.9 9.3 0.096 12.6 9.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit STAG PF08514.11 OAJ27769.1 - 0.16 11.9 2.8 0.12 12.2 1.4 1.5 1 1 0 1 1 1 0 STAG domain DUF4337 PF14235.6 OAJ27769.1 - 0.4 10.8 2.8 0.5 10.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Conotoxin PF02950.17 OAJ27769.1 - 0.47 11.5 2.0 1 10.5 0.8 2.0 1 1 1 2 2 2 0 Conotoxin Connexin PF00029.19 OAJ27769.1 - 0.51 10.1 1.4 0.57 9.9 1.4 1.1 1 0 0 1 1 1 0 Connexin DUF1682 PF07946.14 OAJ27769.1 - 0.77 8.9 9.9 0.94 8.6 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3824 PF12868.7 OAJ27769.1 - 4.6 7.9 17.4 5.8 7.6 9.8 2.0 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Presenilin PF01080.17 OAJ27769.1 - 6.4 5.4 6.9 6.9 5.3 6.9 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 OAJ27769.1 - 7 4.8 26.6 1.2 7.4 23.2 1.4 1 1 0 1 1 1 0 Atrophin-1 family Fringe PF02434.16 OAJ27770.1 - 1.1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 OAJ27770.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Glyco_tranf_2_4 PF13704.6 OAJ27770.1 - 0.26 11.8 1.7 1.1 9.9 0.1 2.5 2 1 0 2 2 2 0 Glycosyl transferase family 2 RRM_1 PF00076.22 OAJ27772.1 - 8.5e-56 185.7 0.0 1.4e-17 63.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ27772.1 - 1.6e-05 24.9 0.0 0.58 10.2 0.0 3.3 3 0 0 3 3 3 3 RNA binding motif DUF3343 PF11823.8 OAJ27772.1 - 0.015 14.7 0.0 0.052 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) DUF3344 PF11824.8 OAJ27772.1 - 0.018 14.7 0.1 0.082 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3344) ATP-grasp_2 PF08442.10 OAJ27772.1 - 0.041 13.4 0.0 5.4 6.5 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp domain Macoilin PF09726.9 OAJ27772.1 - 2.7 6.4 9.6 3.5 6.1 9.6 1.1 1 0 0 1 1 1 0 Macoilin family LAP1C PF05609.12 OAJ27772.1 - 3.3 6.7 8.1 4.5 6.3 8.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 OAJ27772.1 - 4.9 5.2 7.7 6.5 4.7 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ArsA_ATPase PF02374.15 OAJ27773.1 - 1.8e-109 365.6 0.1 2.1e-109 365.4 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 OAJ27773.1 - 1.6e-11 44.4 0.2 4.4e-11 43.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 OAJ27773.1 - 2.3e-10 40.6 0.0 4.2e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 OAJ27773.1 - 1.9e-05 24.2 0.2 0.0003 20.3 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 OAJ27773.1 - 2.7e-05 23.8 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 OAJ27773.1 - 5.3e-05 22.8 0.0 0.00013 21.5 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 OAJ27773.1 - 0.0006 19.5 0.4 0.0053 16.4 0.2 2.2 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 OAJ27773.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 OAJ27773.1 - 0.0096 16.5 0.0 0.076 13.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ27773.1 - 0.014 15.8 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 OAJ27773.1 - 0.03 14.0 0.0 0.098 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ27773.1 - 0.064 12.7 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Alba PF01918.21 OAJ27775.1 - 6.8e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alba SNARE_assoc PF09335.11 OAJ27776.1 - 7.2e-18 65.2 7.0 7.2e-18 65.2 7.0 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4022 PF13214.6 OAJ27776.1 - 0.14 12.4 1.7 0.38 11.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4022) GREB1 PF15782.5 OAJ27776.1 - 1.8 5.6 11.3 3.1 4.8 11.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SpoIIP PF07454.11 OAJ27776.1 - 5.1 6.5 17.8 2.1 7.7 13.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) adh_short PF00106.25 OAJ27777.1 - 5.3e-18 65.2 0.1 1.8e-06 27.5 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ27777.1 - 1.6e-13 50.8 0.1 3e-08 33.5 0.0 2.4 1 1 2 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ27777.1 - 3.3e-05 23.9 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ27777.1 - 0.061 13.2 0.4 0.73 9.7 0.0 2.2 1 1 1 2 2 2 0 NAD(P)H-binding ubiquitin PF00240.23 OAJ27777.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin family Methyltransf_16 PF10294.9 OAJ27778.1 - 4.6e-06 26.5 0.0 6.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cellulase PF00150.18 OAJ27780.1 - 2.1e-16 60.2 0.0 4.2e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 OAJ27781.1 - 1.3e-14 54.4 9.4 4.5e-14 52.6 9.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PGF-CTERM PF18204.1 OAJ27781.1 - 2.1 8.4 5.1 4.5 7.4 5.1 1.5 1 0 0 1 1 1 0 PGF-CTERM motif tRNA-synt_2 PF00152.20 OAJ27782.1 - 7.9e-87 291.3 0.0 5.9e-43 147.1 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ27782.1 - 3.7e-08 33.2 0.0 6.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Transposase_21 PF02992.14 OAJ27784.1 - 4.3e-12 45.7 0.1 1.1e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 Retrotrans_gag PF03732.17 OAJ27785.1 - 0.017 15.4 0.2 0.021 15.1 0.2 1.2 1 0 0 1 1 1 0 Retrotransposon gag protein Abhydrolase_3 PF07859.13 OAJ27786.1 - 2.1e-29 102.9 0.1 2e-20 73.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold CDC45 PF02724.14 OAJ27787.1 - 0.036 12.4 0.1 0.049 11.9 0.1 1.3 1 1 0 1 1 1 0 CDC45-like protein Cadherin_5 PF17892.1 OAJ27787.1 - 0.13 12.2 0.2 0.8 9.7 0.0 2.2 2 1 0 2 2 2 0 Cadherin-like domain Pkinase PF00069.25 OAJ27788.1 - 3.6e-39 134.7 0.0 5.3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27788.1 - 4.6e-25 88.4 0.0 6.7e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ27788.1 - 0.0006 18.7 0.0 0.0014 17.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ27788.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ27788.1 - 0.04 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 OAJ27788.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PS_Dcarbxylase PF02666.15 OAJ27789.1 - 2.2e-42 144.9 0.0 2.8e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase adh_short_C2 PF13561.6 OAJ27790.1 - 1.8e-37 129.2 0.4 8.4e-25 87.7 0.6 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ27790.1 - 3.5e-32 111.4 1.2 4.7e-32 111.0 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ27790.1 - 3.1e-17 63.1 0.3 1.1e-16 61.2 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ27790.1 - 0.0017 17.9 0.2 0.0029 17.1 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ27790.1 - 0.006 16.0 0.0 0.0091 15.4 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OAJ27790.1 - 0.048 13.5 1.5 0.084 12.8 1.1 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cutinase PF01083.22 OAJ27791.1 - 2e-23 83.2 0.0 2.4e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase FtsJ PF01728.19 OAJ27792.1 - 4.3e-40 137.7 0.0 5.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-CCHC_2 PF13696.6 OAJ27793.1 - 3.2e-12 46.0 11.6 1e-08 34.9 4.0 2.4 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 OAJ27793.1 - 1.1e-07 32.7 0.1 1.8e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 OAJ27793.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 zf-CCHC PF00098.23 OAJ27793.1 - 0.0087 16.1 0.3 0.027 14.5 0.3 1.9 1 0 0 1 1 1 1 Zinc knuckle DFP PF04127.15 OAJ27794.1 - 8.6e-20 71.4 0.0 4.9e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 OAJ27794.1 - 0.0017 18.8 0.0 0.078 13.4 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Amidase PF01425.21 OAJ27795.1 - 3.3e-57 194.5 0.9 6.8e-55 186.8 0.7 2.2 2 0 0 2 2 2 2 Amidase ubiquitin PF00240.23 OAJ27797.1 - 1.6e-08 34.2 0.1 2.6e-08 33.5 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ27797.1 - 1e-05 25.9 0.1 6.5e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 OAJ27797.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 OAJ27797.1 - 0.053 13.6 0.1 0.25 11.4 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain PI3K_rbd PF00794.18 OAJ27797.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain 2OG-FeII_Oxy_3 PF13640.6 OAJ27799.1 - 0.089 13.7 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BLIP PF07467.11 OAJ27799.1 - 0.15 12.7 0.1 0.62 10.7 0.1 1.9 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) Oxysterol_BP PF01237.18 OAJ27800.1 - 1.1e-42 146.2 1.2 2.8e-27 95.5 1.1 3.9 2 1 0 2 2 2 2 Oxysterol-binding protein COesterase PF00135.28 OAJ27801.1 - 1.5e-72 245.1 0.2 2.4e-63 214.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ27801.1 - 6.9e-05 22.8 0.1 0.0002 21.3 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Prp18 PF02840.15 OAJ27802.1 - 3.2e-61 205.6 0.0 5.2e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.11 OAJ27802.1 - 1.6e-11 43.5 4.4 3.9e-11 42.3 4.4 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Rad21_Rec8_N PF04825.13 OAJ27805.1 - 1.5e-24 86.2 0.0 2.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 OAJ27805.1 - 1.1e-07 31.0 0.0 2.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SUIM_assoc PF16619.5 OAJ27805.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2236 PF09995.9 OAJ27806.1 - 2e-14 54.4 3.8 2e-14 54.4 3.8 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) Pex24p PF06398.11 OAJ27807.1 - 7e-25 87.8 3.8 7e-25 87.8 3.8 2.8 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF3605 PF12239.8 OAJ27808.1 - 8.8e-05 22.9 0.2 0.00011 22.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) AMP-binding PF00501.28 OAJ27809.1 - 2.3e-09 36.4 0.0 2.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_10 PF13460.6 OAJ27809.1 - 0.0028 17.6 0.1 0.0038 17.1 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding MBOAT_2 PF13813.6 OAJ27810.1 - 4.7e-14 52.4 0.1 3.8e-06 27.1 0.1 3.0 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family Ribophorin_I PF04597.14 OAJ27811.1 - 9.9e-110 367.7 0.1 4.8e-109 365.5 0.1 1.9 1 1 0 1 1 1 1 Ribophorin I WD40 PF00400.32 OAJ27811.1 - 3.7e-07 30.7 5.4 3.8 8.6 0.1 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Sec16 PF12932.7 OAJ27811.1 - 0.032 14.8 0.0 0.11 13.1 0.0 2.0 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Polysacc_deac_1 PF01522.21 OAJ27812.1 - 3.5e-14 52.8 0.0 7.5e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Mt_ATP-synt_B PF05405.14 OAJ27813.1 - 1.6e-46 157.9 7.2 2e-46 157.6 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2730 PF10805.8 OAJ27813.1 - 0.00083 19.4 0.2 0.0014 18.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Cauli_DNA-bind PF03310.13 OAJ27813.1 - 0.082 13.0 2.7 0.08 13.0 1.0 1.7 1 1 1 2 2 2 0 Caulimovirus DNA-binding protein DUF1539 PF07560.11 OAJ27813.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) V_ATPase_I PF01496.19 OAJ27813.1 - 0.44 8.4 4.1 0.56 8.1 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IBR PF01485.21 OAJ27814.1 - 0.00031 20.9 4.4 0.00031 20.9 4.4 3.9 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain HABP4_PAI-RBP1 PF04774.15 OAJ27814.1 - 1.8 9.5 17.7 0.44 11.4 2.5 3.2 3 0 0 3 3 3 0 Hyaluronan / mRNA binding family vMSA PF00695.19 OAJ27814.1 - 2.6 7.0 7.4 5.8 5.9 7.4 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus COX5A PF02284.16 OAJ27815.1 - 1.7e-41 140.4 0.4 2.5e-41 139.9 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF3523 PF12037.8 OAJ27815.1 - 0.062 12.7 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Pilin_N PF07790.11 OAJ27815.1 - 0.22 12.5 1.7 0.43 11.5 1.7 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal RICTOR_N PF14664.6 OAJ27816.1 - 1e-62 212.3 0.0 5.3e-62 210.0 0.0 2.2 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 OAJ27816.1 - 1.9e-31 107.9 1.1 4e-29 100.5 0.5 4.0 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 OAJ27816.1 - 1.4e-28 99.4 0.0 8.4e-28 96.9 0.0 2.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 OAJ27816.1 - 1e-27 96.2 0.3 6e-26 90.5 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 OAJ27816.1 - 3.6e-05 23.8 0.1 8.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 OAJ27816.1 - 0.24 11.8 0.7 1 9.8 0.2 2.5 2 0 0 2 2 2 0 HEAT repeat Coa1 PF08695.10 OAJ27817.1 - 7.2e-30 103.1 0.0 1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TPR_21 PF09976.9 OAJ27817.1 - 0.041 13.6 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain PAP_PilO PF06864.12 OAJ27817.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF1604 PF07713.13 OAJ27818.1 - 8e-35 118.5 8.7 4.3e-34 116.2 8.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.23 OAJ27818.1 - 0.00014 21.6 0.4 0.00049 19.9 0.0 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ27818.1 - 0.0049 16.9 4.3 0.008 16.2 0.1 3.1 3 0 0 3 3 3 1 G-patch domain GPI-anchored PF10342.9 OAJ27819.1 - 9.2e-06 26.3 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TubC_N PF18563.1 OAJ27819.1 - 0.15 12.1 0.4 9.1 6.4 0.0 2.8 3 0 0 3 3 3 0 TubC N-terminal docking domain ANAPC4_WD40 PF12894.7 OAJ27820.1 - 0.16 12.3 0.7 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SLD5_C PF16922.5 OAJ27821.1 - 4e-13 49.3 0.0 9.7e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 OAJ27821.1 - 5.6e-05 23.6 0.1 0.00011 22.6 0.1 1.6 1 0 0 1 1 1 1 GINS complex protein 4HBT_3 PF13622.6 OAJ27822.1 - 1.9e-29 103.7 1.5 2.4e-29 103.3 1.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ27822.1 - 0.0008 19.3 0.0 0.0024 17.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA thioesterase Elf1 PF05129.13 OAJ27823.1 - 1.3 9.1 8.3 0.44 10.6 4.0 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 OAJ27823.1 - 1.9 8.5 12.1 2.8 7.9 4.5 2.7 2 1 0 2 2 2 0 SprT-like zinc ribbon domain SSF PF00474.17 OAJ27824.1 - 6.2e-24 84.6 34.4 6.2e-24 84.6 34.4 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family ABC_membrane PF00664.23 OAJ27825.1 - 5.3e-45 154.2 33.0 2e-27 96.5 12.8 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ27825.1 - 3.8e-41 140.8 0.0 3.3e-26 92.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ27825.1 - 3.1e-08 33.3 3.3 0.013 14.9 0.1 4.5 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ27825.1 - 0.00018 22.1 0.0 0.8 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ27825.1 - 0.00035 20.2 0.3 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ27825.1 - 0.0016 18.7 0.6 2 8.7 0.1 3.4 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAJ27825.1 - 0.011 15.9 0.2 0.011 15.9 0.2 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_7 PF12775.7 OAJ27825.1 - 0.015 14.8 0.4 0.66 9.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 OAJ27825.1 - 0.017 15.5 0.1 0.21 12.0 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAJ27825.1 - 0.025 14.5 0.3 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 OAJ27825.1 - 0.051 14.0 0.3 4.9 7.6 0.2 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 OAJ27825.1 - 0.084 12.6 0.4 13 5.4 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 OAJ27825.1 - 0.099 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ27825.1 - 0.11 12.4 0.2 16 5.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 OAJ27825.1 - 0.13 11.6 0.4 12 5.1 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF5506 PF17611.2 OAJ27825.1 - 0.18 11.7 2.9 0.2 11.6 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5506) AAA_18 PF13238.6 OAJ27825.1 - 0.2 12.2 0.2 3.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ27825.1 - 0.2 12.0 1.0 3.5 8.1 0.0 2.8 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.6 OAJ27825.1 - 0.4 10.8 3.3 19 5.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain Tcp11 PF05794.13 OAJ27826.1 - 1.5e-08 34.2 0.1 3.5e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 T-complex protein 11 Phage_r1t_holin PF16945.5 OAJ27826.1 - 0.047 13.9 0.6 0.047 13.9 0.6 2.2 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin Sod_Fe_C PF02777.18 OAJ27827.1 - 5.6e-35 119.6 0.2 1.2e-34 118.5 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ27827.1 - 2.5e-32 111.2 3.1 4.7e-32 110.3 3.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RRM_1 PF00076.22 OAJ27828.1 - 3e-58 193.5 0.0 1.3e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ27828.1 - 6.1e-11 42.0 0.0 5e-05 22.9 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ27828.1 - 1e-06 28.5 0.0 0.00019 21.2 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ27828.1 - 4.4e-05 23.5 0.0 0.11 12.6 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ27828.1 - 0.00026 20.9 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 OAJ27828.1 - 0.00074 19.8 0.0 0.06 13.6 0.0 2.7 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter SET_assoc PF11767.8 OAJ27828.1 - 0.013 15.2 0.0 0.47 10.1 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Cas_Cas2CT1978 PF09707.10 OAJ27828.1 - 0.043 13.9 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF4523 PF15023.6 OAJ27828.1 - 0.28 11.0 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) TP6A_N PF04406.14 OAJ27829.1 - 1.5e-15 56.9 0.2 9.9e-15 54.3 0.0 2.1 2 0 0 2 2 2 1 Type IIB DNA topoisomerase zf-UBR PF02207.20 OAJ27830.1 - 6.4e-12 45.5 11.1 6.4e-12 45.5 11.1 3.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.29 OAJ27830.1 - 0.0005 19.9 2.9 0.0005 19.9 2.9 3.2 3 0 0 3 3 3 1 PHD-finger Zf_RING PF16744.5 OAJ27830.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger Band_3_cyto PF07565.13 OAJ27831.1 - 2.1 8.1 5.5 2.5 7.8 1.3 2.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Sel1 PF08238.12 OAJ27832.1 - 2.8e-37 126.3 29.6 5.7e-06 26.8 0.8 8.6 8 0 0 8 8 8 7 Sel1 repeat TPR_19 PF14559.6 OAJ27832.1 - 0.044 14.3 4.8 1.3 9.6 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ27832.1 - 0.16 12.6 2.7 2.8 8.7 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 OAJ27833.1 - 3.5e-67 226.8 35.5 4.7e-67 226.4 35.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family zf-C2H2 PF00096.26 OAJ27834.1 - 4.1e-10 39.6 11.8 0.012 16.0 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ27834.1 - 9.1e-09 35.4 9.4 0.014 16.2 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ27834.1 - 8.5e-08 32.3 13.5 0.0017 18.7 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 OAJ27834.1 - 7.8e-06 25.7 3.2 0.0013 18.6 0.1 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger DUF2722 PF10846.8 OAJ27834.1 - 0.0011 18.1 6.1 0.0022 17.0 6.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) zf-met PF12874.7 OAJ27834.1 - 0.0063 16.9 9.3 0.089 13.2 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 OAJ27834.1 - 0.091 13.1 4.6 0.29 11.5 3.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 OAJ27834.1 - 0.1 12.9 9.6 0.25 11.7 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Biotin_carb_N PF00289.22 OAJ27834.1 - 0.19 12.3 0.2 0.5 10.9 0.2 1.6 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain zf-C2HC PF01530.18 OAJ27834.1 - 1.5 9.0 7.6 15 5.8 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2HC type zf-C2H2_aberr PF17017.5 OAJ27834.1 - 1.7 8.8 2.9 37 4.4 0.6 2.7 1 1 2 3 3 3 0 Aberrant zinc-finger SIT PF15330.6 OAJ27834.1 - 8.6 6.8 10.1 0.52 10.8 3.2 2.4 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Pex16 PF08610.10 OAJ27836.1 - 6.5e-111 370.6 0.0 1.5e-110 369.4 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) KfrA_N PF11740.8 OAJ27836.1 - 0.16 12.7 1.2 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term RTC PF01137.21 OAJ27837.1 - 8.8e-51 172.2 0.0 1.1e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 OAJ27837.1 - 2.8e-33 114.5 0.0 5e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ribosomal_S2 PF00318.20 OAJ27838.1 - 3.8e-52 176.7 0.0 5.2e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 HSP70 PF00012.20 OAJ27839.1 - 3.9e-230 765.1 7.4 4.7e-230 764.8 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ27839.1 - 1.4e-18 66.8 0.8 9.7e-18 64.1 0.7 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 OAJ27839.1 - 0.00082 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 OAJ27839.1 - 0.0036 16.3 0.3 0.043 12.8 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 OAJ27839.1 - 0.011 15.1 0.4 0.024 13.9 0.4 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase ATP-synt_DE PF00401.20 OAJ27839.1 - 0.19 12.0 3.0 4.6 7.6 2.7 2.9 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Cpn60_TCP1 PF00118.24 OAJ27840.1 - 5.8e-150 500.1 2.7 6.6e-150 500.0 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 OAJ27840.1 - 0.045 13.3 0.1 0.26 10.9 0.1 2.3 3 0 0 3 3 3 0 Propionate catabolism activator Nitro_FeMo-Co PF02579.17 OAJ27840.1 - 0.097 13.0 0.1 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Adaptin_N PF01602.20 OAJ27842.1 - 6.3e-100 335.2 0.0 4.9e-99 332.3 0.0 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ27842.1 - 3e-08 33.9 0.2 3.1e-06 27.3 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 OAJ27842.1 - 0.00086 19.5 0.1 0.48 10.6 0.0 3.2 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 OAJ27842.1 - 0.019 15.2 3.2 21 5.7 0.0 5.2 4 1 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 OAJ27842.1 - 0.026 14.9 11.9 0.11 12.9 0.1 4.7 5 0 0 5 5 5 0 HEAT repeats Cnd3 PF12719.7 OAJ27842.1 - 0.058 12.6 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OAJ27842.1 - 0.13 12.3 1.3 34 4.7 0.1 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat LRR_9 PF14580.6 OAJ27843.1 - 2.8e-60 202.8 0.0 3.8e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 OAJ27843.1 - 3.9e-13 49.4 12.5 3.7e-07 30.4 0.7 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ27843.1 - 1.1e-11 44.3 9.8 7.9e-07 28.7 1.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat tRNA_bind_3 PF17176.4 OAJ27843.1 - 0.016 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 tRNA-binding domain LRR_6 PF13516.6 OAJ27843.1 - 0.026 14.6 0.0 36 4.8 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat MRP-S33 PF08293.11 OAJ27844.1 - 5e-20 71.5 0.4 1.9e-19 69.7 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Tim17 PF02466.19 OAJ27845.1 - 7.4e-09 36.0 1.3 8.7e-09 35.8 0.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family His_Phos_2 PF00328.22 OAJ27846.1 - 3.3e-17 62.9 0.0 6.7e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NepR PF18557.1 OAJ27846.1 - 0.33 10.6 1.5 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma factor NepR Catalase PF00199.19 OAJ27848.1 - 9.2e-161 535.2 0.1 1.1e-160 534.9 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ27848.1 - 8.7e-14 51.5 0.2 2.8e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Disaggr_repeat PF06848.11 OAJ27848.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat TPR_2 PF07719.17 OAJ27849.1 - 2.4e-29 99.1 13.3 6.7e-05 22.7 0.1 10.1 11 0 0 11 11 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ27849.1 - 2.8e-24 85.1 6.0 5.6e-09 36.1 0.5 5.8 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 OAJ27849.1 - 4e-21 73.9 9.6 0.00013 21.7 0.1 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27849.1 - 3.2e-18 64.4 6.7 2.5e-05 24.1 0.1 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ27849.1 - 1.7e-15 57.0 15.5 1.5e-05 25.2 0.2 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ27849.1 - 1.9e-13 49.8 0.5 2.1 8.9 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ27849.1 - 7.5e-12 45.7 22.8 0.002 18.7 0.0 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ27849.1 - 5.6e-11 41.9 9.6 0.11 12.2 0.0 8.3 9 1 1 10 10 10 3 TPR repeat TPR_19 PF14559.6 OAJ27849.1 - 6.1e-11 42.7 18.9 0.61 10.6 0.0 8.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ27849.1 - 1.4e-10 41.1 26.9 0.17 12.8 1.0 9.6 6 2 4 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ27849.1 - 1.6e-05 25.2 23.1 1 10.2 0.2 8.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ27849.1 - 2.1e-05 24.2 12.1 16 5.8 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27849.1 - 0.0013 18.9 10.4 0.31 11.2 0.2 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ27849.1 - 0.002 18.0 12.1 0.83 9.6 0.3 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ27849.1 - 0.031 13.6 11.2 0.053 12.9 0.5 4.6 5 1 1 6 6 6 0 MalT-like TPR region TPR_21 PF09976.9 OAJ27849.1 - 0.15 11.7 2.1 14 5.4 0.0 4.0 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain bZIP_1 PF00170.21 OAJ27850.1 - 0.0052 16.9 8.3 0.0052 16.9 8.3 2.6 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ27850.1 - 0.013 15.6 6.7 0.013 15.6 6.7 3.2 3 0 0 3 3 3 0 Basic region leucine zipper Sec62 PF03839.16 OAJ27850.1 - 0.26 10.8 0.9 0.55 9.7 0.9 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Activator_LAG-3 PF11498.8 OAJ27850.1 - 1 8.3 33.5 2.5 6.9 33.5 1.7 1 0 0 1 1 1 0 Transcriptional activator LAG-3 YebO PF13974.6 OAJ27850.1 - 1.7 8.8 13.6 5 7.3 13.6 1.8 1 0 0 1 1 1 0 YebO-like protein TERB2 PF15101.6 OAJ27850.1 - 2.7 8.0 11.2 6.5 6.7 11.2 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MBOAT_2 PF13813.6 OAJ27851.1 - 6.7e-10 39.1 2.6 1.7e-07 31.4 2.6 2.8 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.25 OAJ27852.1 - 1.1e-20 74.0 0.0 3.3e-20 72.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ27852.1 - 1.7e-16 60.5 0.1 2.5e-15 56.7 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ27852.1 - 5.3e-05 23.2 0.3 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Pyr_redox_2 PF07992.14 OAJ27852.1 - 0.018 14.2 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ27852.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.32 OAJ27853.1 - 1.1e-35 121.1 14.1 9.8e-05 23.1 0.2 10.4 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ27853.1 - 3.2e-15 56.2 0.3 2.4e-05 24.5 0.0 5.9 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ27853.1 - 0.0012 17.6 0.0 0.012 14.3 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ27853.1 - 0.0012 17.7 0.1 0.44 9.2 0.0 3.3 3 1 0 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 OAJ27853.1 - 0.0074 15.7 0.1 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 OAJ27853.1 - 0.022 13.7 3.6 6.2 5.7 0.2 4.2 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 OAJ27853.1 - 0.06 13.3 6.7 12 6.1 0.1 5.0 6 0 0 6 6 6 0 PQQ enzyme repeat WD40_like PF17005.5 OAJ27853.1 - 0.072 12.4 0.0 12 5.1 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain Utp8 PF10395.9 OAJ27853.1 - 0.14 10.6 0.0 2.2 6.7 0.0 2.0 2 0 0 2 2 2 0 Utp8 family PQQ_3 PF13570.6 OAJ27853.1 - 0.24 11.9 18.7 4.6 7.9 0.0 6.6 6 1 0 6 6 6 0 PQQ-like domain HEAT_EZ PF13513.6 OAJ27854.1 - 2e-24 85.7 15.9 3.9e-12 46.4 0.0 9.1 8 2 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 OAJ27854.1 - 8.6e-16 56.7 15.8 0.009 16.2 0.0 9.3 10 0 0 10 10 8 4 HEAT repeat HEAT_2 PF13646.6 OAJ27854.1 - 9e-15 54.8 5.6 0.00018 21.8 0.0 7.4 5 3 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.7 OAJ27854.1 - 1.3e-10 41.8 0.0 0.0022 18.6 0.0 4.9 3 2 1 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ27854.1 - 7.8e-07 29.3 0.0 0.014 15.4 0.0 4.8 5 2 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 OAJ27854.1 - 2.1e-06 27.2 9.5 0.0055 15.9 0.1 4.5 4 1 1 5 5 5 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 OAJ27854.1 - 2.7e-05 24.3 0.1 0.00021 21.4 0.0 2.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 OAJ27854.1 - 7.1e-05 22.7 0.0 0.00028 20.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3437 PF11919.8 OAJ27854.1 - 0.00012 21.9 0.1 0.87 9.5 0.0 4.2 4 1 1 5 5 5 2 Domain of unknown function (DUF3437) Arm PF00514.23 OAJ27854.1 - 0.0017 18.3 8.6 0.71 10.0 0.0 5.3 6 0 0 6 6 5 2 Armadillo/beta-catenin-like repeat ParcG PF10274.9 OAJ27854.1 - 0.0027 17.8 0.1 2.8 8.0 0.0 3.4 2 1 1 3 3 3 1 Parkin co-regulated protein DUF3385 PF11865.8 OAJ27854.1 - 0.0033 17.4 0.1 2.5 8.0 0.0 4.7 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) Cnd3 PF12719.7 OAJ27854.1 - 0.023 13.9 0.3 2.1 7.5 0.1 3.4 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain Tti2 PF10521.9 OAJ27854.1 - 0.1 12.1 0.1 8.4 5.8 0.0 2.9 4 0 0 4 4 4 0 Tti2 family Ecm29 PF13001.7 OAJ27854.1 - 0.17 10.5 0.0 5 5.7 0.0 2.7 2 0 0 2 2 2 0 Proteasome stabiliser DUF3295 PF11702.8 OAJ27854.1 - 2.5 7.4 4.5 3.7 6.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TRM PF02005.16 OAJ27855.1 - 6.1e-116 387.7 0.0 2.6e-87 293.5 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF3138 PF11336.8 OAJ27855.1 - 0.26 9.8 3.9 0.43 9.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ferric_reduct PF01794.19 OAJ27856.1 - 2.8e-17 63.0 14.2 5.8e-17 62.0 14.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 OAJ27856.1 - 6.5e-16 58.4 0.0 2e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 OAJ27856.1 - 2.2e-11 44.1 0.0 6.9e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Hamartin PF04388.12 OAJ27856.1 - 3.1 6.3 7.6 6.7 5.2 7.6 1.4 1 0 0 1 1 1 0 Hamartin protein Phytase-like PF13449.6 OAJ27857.1 - 2.2e-35 123.0 0.3 3.4e-35 122.4 0.3 1.3 1 1 0 1 1 1 1 Esterase-like activity of phytase PQQ PF01011.21 OAJ27857.1 - 0.032 14.2 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat Asp PF00026.23 OAJ27858.1 - 1.5e-72 244.7 0.2 2.2e-72 244.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ27858.1 - 1.7e-11 44.7 0.2 9.9e-09 35.7 0.2 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal KdgM PF06178.13 OAJ27858.1 - 0.22 11.1 0.1 0.45 10.1 0.0 1.5 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) GDP_Man_Dehyd PF16363.5 OAJ27859.1 - 8.8e-47 160.1 0.0 7.3e-42 143.9 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 OAJ27859.1 - 9.2e-45 153.0 0.0 1.8e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ27859.1 - 7.2e-09 35.0 0.0 1.1e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ27859.1 - 4.1e-08 32.7 0.0 0.00031 20.0 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ27859.1 - 7.2e-08 31.9 0.0 2.3e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 OAJ27859.1 - 2.1e-05 23.8 0.0 0.062 12.4 0.0 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Lum_binding PF00677.17 OAJ27860.1 - 1.8e-36 124.0 0.0 4.3e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain Sld5 PF05916.11 OAJ27861.1 - 7.8e-06 26.3 0.0 1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF410 PF04190.13 OAJ27862.1 - 2.4e-58 197.9 0.0 3.2e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) zf-DNL PF05180.12 OAJ27863.1 - 4.4e-30 103.4 0.0 6.6e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 OAJ27863.1 - 1.2 9.1 3.7 8.3 6.4 0.3 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain PRP1_N PF06424.12 OAJ27864.1 - 4.2e-47 160.3 3.7 1.2e-46 158.8 3.7 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 OAJ27864.1 - 1.3e-26 91.0 27.8 0.011 16.5 0.0 13.9 6 5 8 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ27864.1 - 6.3e-22 77.9 6.9 0.00087 19.8 0.0 8.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ27864.1 - 2.8e-09 37.4 14.9 0.0068 17.0 1.2 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ27864.1 - 1.4e-08 34.2 0.4 12 6.3 0.0 8.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ27864.1 - 2.6e-07 30.7 1.7 0.035 14.3 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ27864.1 - 2.1e-05 24.6 0.2 2.9 8.5 0.0 5.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ27864.1 - 0.00036 21.0 1.7 14 6.6 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ27864.1 - 0.00088 19.3 0.4 55 4.3 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat FAT PF02259.23 OAJ27864.1 - 0.0011 18.3 13.1 0.013 14.7 2.2 4.1 2 1 1 3 3 3 2 FAT domain Suf PF05843.14 OAJ27864.1 - 0.017 15.1 0.6 3.1 7.7 0.0 4.4 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 OAJ27864.1 - 0.16 10.9 7.4 2.3 7.0 0.1 4.5 4 1 2 6 6 6 0 NMDA receptor-regulated protein 1 Helitron_like_N PF14214.6 OAJ27865.1 - 3.4e-61 206.8 0.2 4.7e-61 206.3 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LRR_11 PF18831.1 OAJ27865.1 - 0.072 12.7 0.2 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeat LOR PF04525.12 OAJ27867.1 - 7.3e-15 55.0 0.0 8.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related DUF3137 PF11335.8 OAJ27868.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) G6PD_C PF02781.16 OAJ27869.1 - 6.3e-107 357.1 0.0 8.5e-107 356.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 OAJ27869.1 - 1.8e-59 201.4 0.1 3.1e-59 200.6 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Allantoicase PF03561.15 OAJ27870.1 - 7.4e-85 282.2 0.0 2.8e-42 144.1 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 OAJ27870.1 - 6.4e-54 182.6 0.0 9.6e-54 182.0 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF2985 PF11204.8 OAJ27871.1 - 1.6e-25 89.0 1.7 3.2e-25 88.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.6 OAJ27871.1 - 0.05 13.6 0.7 0.19 11.8 0.1 2.2 2 0 0 2 2 2 0 Putative sensor TssC PF17541.2 OAJ27874.1 - 0.16 10.8 0.4 0.22 10.3 0.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB DUF4461 PF14688.6 OAJ27874.1 - 0.23 11.2 1.7 0.35 10.6 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) LSM PF01423.22 OAJ27875.1 - 1e-14 54.0 0.0 1.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.15 OAJ27876.1 - 1.1e-57 195.4 0.0 3.1e-51 174.3 0.0 2.1 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 OAJ27876.1 - 2.3e-20 72.3 0.0 3.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 OAJ27876.1 - 2.8e-20 72.9 0.0 6.8e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 OAJ27876.1 - 1.1e-14 54.2 6.3 2.1e-14 53.3 6.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 OAJ27876.1 - 0.00039 20.3 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat TTL PF03133.15 OAJ27877.1 - 1.9e-41 142.1 0.0 4.8e-28 98.1 0.0 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family CENP-B_dimeris PF09026.10 OAJ27877.1 - 0.0003 21.1 1.7 0.00066 20.0 1.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Nro1 PF12753.7 OAJ27877.1 - 0.36 9.7 4.0 0.52 9.2 4.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 DUF2457 PF10446.9 OAJ27877.1 - 1 8.4 6.6 1.7 7.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 OAJ27877.1 - 1.8 8.8 6.7 3.5 7.9 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 OAJ27877.1 - 3.1 5.8 8.3 5 5.1 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ27877.1 - 9.7 5.4 8.4 15 4.8 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1129 PF06570.11 OAJ27878.1 - 0.39 10.2 5.1 8.4 5.8 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Pilin_N PF07790.11 OAJ27878.1 - 2.5 9.1 10.9 4.1 8.4 0.1 2.8 2 1 1 3 3 3 0 Archaeal Type IV pilin, N-terminal OTT_1508_deam PF14441.6 OAJ27879.1 - 2e-05 24.5 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase dCMP_cyt_deam_1 PF00383.23 OAJ27879.1 - 0.0035 17.2 0.8 0.0072 16.2 0.2 1.8 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Mod_r PF07200.13 OAJ27880.1 - 0.0024 18.0 0.8 0.0037 17.4 0.8 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Tropomyosin_1 PF12718.7 OAJ27880.1 - 0.0025 18.0 0.4 0.0043 17.2 0.4 1.3 1 0 0 1 1 1 1 Tropomyosin like FTCD_C PF04961.12 OAJ27880.1 - 0.051 13.4 0.1 0.058 13.2 0.1 1.1 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase WRNPLPNID PF15017.6 OAJ27880.1 - 0.12 13.3 0.4 0.17 12.8 0.4 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF1542 PF07564.11 OAJ27880.1 - 0.64 10.2 3.5 6.8 6.9 3.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) IMUP PF15761.5 OAJ27881.1 - 3.2 8.5 9.6 0.4 11.4 3.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein RT_RNaseH_2 PF17919.1 OAJ27884.1 - 1.5e-31 108.4 0.0 3.8e-31 107.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ27884.1 - 1.2e-28 99.5 0.0 2.5e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 OAJ27884.1 - 2.1e-17 63.4 0.0 5.4e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ27884.1 - 3.9e-12 46.1 0.0 8.8e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ27884.1 - 0.011 15.4 0.2 0.069 12.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain DUF87 PF01935.17 OAJ27884.1 - 0.091 12.8 2.4 0.56 10.3 3.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Trehalase_Ca-bi PF07492.11 OAJ27884.1 - 1.1 9.0 3.7 30 4.5 0.3 2.8 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain Asp_protease_2 PF13650.6 OAJ27885.1 - 0.0058 17.2 0.0 0.019 15.6 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 OAJ27885.1 - 0.0088 16.1 3.5 0.015 15.3 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle RVT_1 PF00078.27 OAJ27885.1 - 0.22 11.0 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_2 PF13696.6 OAJ27885.1 - 0.26 11.2 1.6 0.46 10.4 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Peptidase_M43 PF05572.13 OAJ27886.1 - 1.1e-14 54.7 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ27886.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ27886.1 - 0.0019 18.4 1.4 0.0048 17.1 1.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ27886.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Met-zincin Peptidase_M10 PF00413.24 OAJ27886.1 - 0.012 15.4 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 OAJ27886.1 - 0.018 14.7 0.8 0.047 13.3 0.8 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Phos_pyr_kin PF08543.12 OAJ27887.1 - 1.1e-69 234.6 0.1 2.7e-52 177.6 0.1 3.2 2 1 1 3 3 3 3 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 OAJ27887.1 - 5.5e-25 88.4 0.5 3.8e-24 85.7 0.5 2.1 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 OAJ27887.1 - 0.0097 15.3 0.9 0.98 8.7 0.0 2.6 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.24 OAJ27887.1 - 0.055 12.8 0.2 1.6 8.0 0.0 2.7 3 0 0 3 3 3 0 pfkB family carbohydrate kinase Cyclin_C PF02984.19 OAJ27887.1 - 0.17 12.0 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain Adaptin_N PF01602.20 OAJ27888.1 - 4.9e-143 477.5 5.6 5.7e-143 477.2 5.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 OAJ27888.1 - 7.3e-25 87.4 4.0 1.5e-24 86.5 3.9 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 OAJ27888.1 - 7.3e-06 26.1 6.9 0.00026 21.1 0.5 3.3 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ27888.1 - 0.00033 21.0 2.0 3.3 8.2 0.2 4.6 4 1 0 4 4 4 2 HEAT repeats RIX1 PF08167.12 OAJ27888.1 - 0.0066 16.2 0.3 0.21 11.3 0.0 3.2 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 OAJ27888.1 - 0.076 13.3 0.2 1e+02 3.6 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat TGF_beta_GS PF08515.12 OAJ27888.1 - 0.092 12.3 0.3 0.3 10.6 0.3 2.0 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Peptidase_M73 PF12389.8 OAJ27888.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Peptidase_M43 PF05572.13 OAJ27889.1 - 4.9e-16 59.0 0.0 7.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ27889.1 - 4.6e-06 27.1 0.0 9.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ27889.1 - 4.5e-05 23.7 1.0 6.3e-05 23.2 1.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 OAJ27889.1 - 0.0001 22.0 0.3 0.00028 20.6 0.3 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ27889.1 - 0.024 14.5 0.1 0.045 13.6 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.11 OAJ27889.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF4953 PF16313.5 OAJ27889.1 - 0.052 12.8 0.2 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Met-zincin Orn_Arg_deC_N PF02784.16 OAJ27890.1 - 1.3e-24 86.9 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 OAJ27890.1 - 0.0082 16.4 0.1 0.017 15.4 0.1 1.5 1 0 0 1 1 1 1 Arginine decarboxylase helical bundle domain Abhydrolase_1 PF00561.20 OAJ27890.1 - 0.088 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold TAF8_C PF10406.9 OAJ27891.1 - 5e-09 36.6 5.9 1e-06 29.2 4.2 3.1 2 0 0 2 2 2 2 Transcription factor TFIID complex subunit 8 C-term PBP1_TM PF14812.6 OAJ27891.1 - 0.037 14.4 7.6 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Striatin PF08232.12 OAJ27891.1 - 0.5 10.9 3.6 0.95 10.0 3.6 1.4 1 0 0 1 1 1 0 Striatin family K_oxygenase PF13434.6 OAJ27892.1 - 8.7e-08 31.7 0.0 0.0043 16.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 OAJ27892.1 - 0.0026 17.1 0.1 1.5 7.9 0.0 3.2 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ27892.1 - 0.33 9.9 0.0 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein SHE3 PF17078.5 OAJ27893.1 - 1.7e-08 34.5 1.2 3.1e-08 33.6 1.2 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Cep57_CLD_2 PF14197.6 OAJ27893.1 - 0.011 15.8 5.4 0.011 15.8 5.4 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 FPP PF05911.11 OAJ27893.1 - 0.018 13.3 6.0 0.25 9.5 2.9 2.4 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil EzrA PF06160.12 OAJ27893.1 - 0.033 12.4 2.8 0.96 7.5 0.1 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA THOC7 PF05615.13 OAJ27893.1 - 0.08 13.2 0.2 0.08 13.2 0.2 3.7 3 1 2 5 5 5 0 Tho complex subunit 7 COG5 PF10392.9 OAJ27893.1 - 0.11 12.7 2.4 15 5.8 0.9 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Filament PF00038.21 OAJ27893.1 - 0.27 10.8 18.6 1.2 8.6 3.5 3.2 2 1 1 3 3 3 0 Intermediate filament protein DUF4201 PF13870.6 OAJ27893.1 - 0.85 9.3 5.6 0.54 10.0 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 OAJ27893.1 - 0.99 9.5 5.2 2.6 8.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 OAJ27893.1 - 3.7 6.4 15.3 0.14 11.0 1.2 3.1 2 1 0 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 OAJ27893.1 - 6.3 6.8 16.2 3.3 7.8 0.4 3.7 4 0 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HLH PF00010.26 OAJ27894.1 - 1.1e-12 47.6 0.0 6.2e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tyrosinase PF00264.20 OAJ27896.1 - 1.4e-39 136.7 1.2 1.9e-39 136.2 1.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ27898.1 - 5.1e-36 125.0 1.3 5.1e-36 125.0 1.3 1.7 1 1 1 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ27900.1 - 6.6e-40 137.8 2.8 8.4e-40 137.4 2.1 1.4 1 1 1 2 2 2 1 Common central domain of tyrosinase Tyrosinase PF00264.20 OAJ27901.1 - 1.9e-36 126.5 4.3 2.6e-36 126.0 4.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase RAP1 PF07218.11 OAJ27902.1 - 4.2 5.5 4.1 5.7 5.1 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PIF1 PF05970.14 OAJ27903.1 - 3e-47 161.6 0.0 5.7e-47 160.6 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ27903.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ27903.1 - 8.4e-06 26.2 0.1 3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ27903.1 - 0.014 14.3 0.1 0.17 10.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 OAJ27903.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ27903.1 - 0.044 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 OAJ27903.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 OAJ27903.1 - 0.31 10.7 4.7 1.4 8.6 0.3 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Imm65 PF15582.6 OAJ27904.1 - 0.057 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 65 MARVEL PF01284.23 OAJ27905.1 - 1.8e-06 28.0 8.8 2.9e-06 27.4 8.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF805 PF05656.14 OAJ27905.1 - 0.048 14.1 0.1 0.078 13.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) WH1 PF00568.23 OAJ27906.1 - 4.6e-13 49.1 0.0 1.6e-12 47.3 0.0 1.7 1 1 0 1 1 1 1 WH1 domain PBD PF00786.28 OAJ27906.1 - 3.7e-09 36.8 0.0 7.5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Pmp3 PF01679.17 OAJ27907.1 - 9.8e-23 80.1 10.3 1.2e-22 79.9 10.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Phage_int_SAM_1 PF02899.17 OAJ27908.1 - 0.028 14.7 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.22 OAJ27909.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Asp_Arg_Hydrox PF05118.15 OAJ27910.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Leo1 PF04004.13 OAJ27912.1 - 2.4e-41 141.3 0.3 8.9e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein Abhydrolase_1 PF00561.20 OAJ27913.1 - 1.2e-13 51.3 0.1 2.2e-12 47.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ27913.1 - 9.9e-12 45.9 0.0 1.6e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ27913.1 - 3.4e-09 36.3 0.0 2.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ27913.1 - 0.00067 19.4 0.0 0.00067 19.4 0.0 2.0 2 1 0 2 2 2 1 Putative esterase Peptidase_S9 PF00326.21 OAJ27913.1 - 0.003 17.0 0.0 0.053 13.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ27913.1 - 0.0087 15.9 0.2 0.34 10.7 0.1 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 OAJ27913.1 - 0.035 13.6 1.9 1.1 8.7 0.0 2.8 3 0 0 3 3 3 0 Esterase PHB depolymerase PGAP1 PF07819.13 OAJ27913.1 - 0.16 11.7 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein PepSY_TM_like_2 PF16357.5 OAJ27913.1 - 0.3 11.1 1.7 0.62 10.0 1.7 1.5 1 0 0 1 1 1 0 Putative PepSY_TM-like DUF4407 PF14362.6 OAJ27913.1 - 6.8 5.9 14.3 0.37 10.1 7.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) BP28CT PF08146.12 OAJ27914.1 - 4.7e-37 127.3 1.1 2.4e-36 124.9 1.1 2.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain Fanconi_A_N PF15865.5 OAJ27914.1 - 0.048 13.1 0.1 0.048 13.1 0.1 3.7 3 0 0 3 3 3 0 Fanconi anaemia group A protein N terminus CLASP_N PF12348.8 OAJ27914.1 - 0.13 11.8 7.2 3.5 7.1 0.1 3.7 3 0 0 3 3 3 0 CLASP N terminal DUF3385 PF11865.8 OAJ27914.1 - 0.13 12.2 8.6 0.58 10.0 0.1 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) DUF3361 PF11841.8 OAJ27914.1 - 0.29 11.0 5.3 0.2 11.6 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT PF02985.22 OAJ27914.1 - 0.42 11.0 2.8 49 4.6 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 OAJ27914.1 - 0.79 10.1 7.1 16 6.0 0.1 5.4 4 0 0 4 4 4 0 HEAT repeats RVT_1 PF00078.27 OAJ27915.1 - 1.1e-20 74.2 0.1 2.1e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ27915.1 - 0.0083 16.7 0.0 0.024 15.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RRF PF01765.19 OAJ27916.1 - 2.7e-32 112.0 0.1 4.5e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Ribosomal_S6 PF01250.17 OAJ27916.1 - 0.16 12.3 0.2 0.66 10.3 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein S6 PBP1_TM PF14812.6 OAJ27916.1 - 4.2 7.8 13.2 0.12 12.8 6.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tho2 PF11262.8 OAJ27916.1 - 4.4 6.4 5.4 7.2 5.7 5.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-CCHC PF00098.23 OAJ27917.1 - 7.6e-48 158.5 63.9 2.8e-07 30.3 2.1 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ27917.1 - 7.1e-12 45.1 31.1 0.11 12.5 0.0 7.0 4 2 2 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ27917.1 - 2.8e-11 43.0 43.2 0.019 14.7 1.5 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 OAJ27917.1 - 5.5e-05 22.9 12.3 0.0017 18.2 0.7 7.1 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ27917.1 - 0.00043 19.9 36.9 0.19 11.5 0.7 7.0 7 0 0 7 7 7 5 GAG-polyprotein viral zinc-finger Sporozoite_P67 PF05642.11 OAJ27918.1 - 1.4 6.9 10.4 1.7 6.6 10.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NUDE_C PF04880.13 OAJ27918.1 - 6.2 7.3 7.6 11 6.5 7.6 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region VCBS PF13517.6 OAJ27919.1 - 5.8e-20 71.6 13.6 3.4e-06 27.5 0.5 5.5 3 2 3 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 OAJ27919.1 - 4.8e-09 36.2 4.9 0.0035 17.4 0.0 5.7 5 0 0 5 5 5 3 FG-GAP repeat Cauli_VI PF01693.16 OAJ27920.1 - 4.5e-15 55.7 1.7 8.1e-15 54.9 1.7 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin TauD PF02668.16 OAJ27921.1 - 6.9e-32 111.3 2.3 6.9e-32 111.3 0.1 2.1 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 OAJ27921.1 - 4.1e-14 53.0 1.9 4.1e-13 49.8 0.0 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF971) Pex14_N PF04695.13 OAJ27921.1 - 6.4 7.4 18.3 1.8 9.2 3.0 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAD_binding_7 PF03441.14 OAJ27922.1 - 5.4e-48 163.2 0.9 1.2e-45 155.5 0.9 2.3 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ27922.1 - 3e-35 121.6 0.0 5.1e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-H2C2_2 PF13465.6 OAJ27923.1 - 6.1e-11 42.2 9.4 0.00014 22.1 0.3 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ27923.1 - 1e-10 41.5 9.7 0.0011 19.7 0.0 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ27923.1 - 1.1e-08 35.0 23.1 0.00066 20.0 0.0 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAJ27923.1 - 0.007 16.3 4.5 0.12 12.4 0.0 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2HC_2 PF13913.6 OAJ27923.1 - 0.031 14.2 0.9 0.031 14.2 0.9 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type IBR PF01485.21 OAJ27923.1 - 0.11 12.8 1.7 0.27 11.5 1.7 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_jaz PF12171.8 OAJ27923.1 - 0.44 10.9 16.1 1 9.8 0.0 5.3 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding TFIIA PF03153.13 OAJ27923.1 - 1.7 8.5 38.6 0.012 15.6 11.2 2.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit zf-BED PF02892.15 OAJ27923.1 - 6.2 6.9 7.6 0.4 10.7 0.2 2.8 3 0 0 3 3 3 0 BED zinc finger Glyco_hydro_cc PF11790.8 OAJ27924.1 - 2.4e-49 168.1 1.7 3e-49 167.8 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Mito_carr PF00153.27 OAJ27926.1 - 2.9e-17 62.3 2.2 1.4e-05 24.9 0.0 5.3 5 0 0 5 5 5 5 Mitochondrial carrier protein DDE_Tnp_1_6 PF13751.6 OAJ27926.1 - 0.031 14.5 0.1 0.051 13.8 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain TMEM214 PF10151.9 OAJ27926.1 - 0.33 9.3 1.4 0.49 8.8 1.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator COE1_HLH PF16423.5 OAJ27928.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain V-ATPase_G PF03179.15 OAJ27929.1 - 0.0054 17.2 0.3 0.0054 17.2 0.3 2.3 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit FA_desaturase PF00487.24 OAJ27930.1 - 0.00043 20.2 10.2 0.00043 20.2 10.2 1.5 2 0 0 2 2 2 1 Fatty acid desaturase MIS13 PF08202.11 OAJ27931.1 - 1.7e-17 63.6 0.0 1.9e-14 53.7 0.0 3.4 2 1 0 2 2 2 2 Mis12-Mtw1 protein family HEAT PF02985.22 OAJ27932.1 - 5.5e-22 76.0 22.3 0.085 13.2 0.0 17.4 18 0 0 18 18 18 4 HEAT repeat HEAT_2 PF13646.6 OAJ27932.1 - 1.6e-17 63.7 39.5 0.00023 21.5 0.0 13.1 10 3 2 13 13 12 5 HEAT repeats HEAT_EZ PF13513.6 OAJ27932.1 - 1.1e-13 51.4 39.0 0.00023 21.6 0.0 15.0 16 2 2 18 18 16 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ27932.1 - 3.5e-08 33.9 0.0 0.021 15.4 0.0 5.5 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 OAJ27932.1 - 6.4e-07 29.2 0.0 0.00027 20.6 0.0 3.9 2 1 1 3 3 3 1 CLASP N terminal IFRD PF05004.13 OAJ27932.1 - 1.4e-05 24.3 4.2 2.5 7.1 0.0 6.4 7 0 0 7 7 7 1 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 OAJ27932.1 - 5.4e-05 23.4 3.7 0.1 12.9 0.0 5.4 6 0 0 6 6 5 1 HEAT repeat associated with sister chromatid cohesion Ecm29 PF13001.7 OAJ27932.1 - 0.0012 17.7 0.5 1.7 7.2 0.0 3.2 2 1 1 3 3 3 2 Proteasome stabiliser RTP1_C1 PF10363.9 OAJ27932.1 - 0.0031 17.7 2.7 9.1 6.5 0.0 5.3 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 DRIM PF07539.12 OAJ27932.1 - 0.0056 15.0 7.2 0.028 12.7 0.0 4.4 3 1 1 4 4 4 1 Down-regulated in metastasis Cnd3 PF12719.7 OAJ27932.1 - 0.024 13.8 0.1 12 5.0 0.0 3.3 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF3437 PF11919.8 OAJ27932.1 - 0.076 12.9 0.0 9.7 6.2 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Arm PF00514.23 OAJ27932.1 - 0.84 9.8 3.8 1.1e+02 3.0 0.0 5.0 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat VID27_PH PF17747.1 OAJ27933.1 - 1.3e-15 57.6 0.2 1.9e-15 57.0 0.2 1.3 1 0 0 1 1 1 1 VID27 PH-like domain VID27_N PF17748.1 OAJ27933.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.5 2 0 0 2 2 2 0 VID27 N-terminal region VID27 PF08553.10 OAJ27934.1 - 3.1e-151 503.5 0.0 4.6e-151 502.9 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 OAJ27934.1 - 3.9e-38 131.0 0.0 3.9e-38 131.0 0.0 3.7 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 OAJ27934.1 - 2.2e-26 92.2 3.2 6.5e-26 90.8 3.2 1.9 1 0 0 1 1 1 1 VID27 PH-like domain YL1 PF05764.13 OAJ27934.1 - 0.32 11.1 34.9 0.058 13.5 22.3 2.4 2 0 0 2 2 2 0 YL1 nuclear protein FAM176 PF14851.6 OAJ27934.1 - 3.8 7.2 18.0 3.8 7.2 2.0 3.7 3 0 0 3 3 3 0 FAM176 family Transposase_21 PF02992.14 OAJ27936.1 - 1.4e-17 63.6 0.0 3e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Spindle_Spc25 PF08234.12 OAJ27937.1 - 1.6e-15 57.1 0.0 4.1e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Creb_binding PF09030.10 OAJ27937.1 - 0.011 16.5 2.4 0.011 16.5 2.4 3.3 3 1 0 3 3 3 0 Creb binding Macoilin PF09726.9 OAJ27937.1 - 0.049 12.2 4.0 0.057 12.0 4.0 1.1 1 0 0 1 1 1 0 Macoilin family CENP-F_leu_zip PF10473.9 OAJ27937.1 - 0.12 12.4 11.2 0.22 11.5 11.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 OAJ27937.1 - 0.31 8.9 0.8 0.37 8.6 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4936 PF16290.5 OAJ27937.1 - 0.39 11.4 4.4 0.89 10.3 2.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4936) DUF4407 PF14362.6 OAJ27937.1 - 0.48 9.7 10.2 0.72 9.1 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 OAJ27937.1 - 1.8 7.6 8.5 3.3 6.7 8.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 OAJ27937.1 - 1.8 7.3 12.4 9.4 5.0 12.4 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 OAJ27937.1 - 9.9 6.4 9.0 2.3 8.4 1.1 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Pkinase PF00069.25 OAJ27939.1 - 1.6e-59 201.4 0.0 1e-58 198.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ27939.1 - 9.1e-28 97.2 0.0 1.9e-18 66.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ27939.1 - 0.00098 18.5 0.1 0.28 10.4 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 OAJ27939.1 - 0.0083 16.1 0.5 0.18 11.7 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 OAJ27939.1 - 0.012 14.9 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 OAJ27939.1 - 0.021 15.5 0.1 0.073 13.8 0.1 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAJ27939.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Myc-LZ PF02344.15 OAJ27939.1 - 0.059 13.5 4.5 4.7 7.4 1.1 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain RIO1 PF01163.22 OAJ27939.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Herpes_TAF50 PF03326.13 OAJ27939.1 - 0.92 8.1 9.0 1.3 7.5 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) ABC_membrane PF00664.23 OAJ27940.1 - 1.4e-38 133.1 6.7 1.8e-38 132.8 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ27940.1 - 2.9e-33 115.3 0.0 6.6e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 OAJ27940.1 - 0.00059 19.3 0.2 0.25 10.7 0.0 2.8 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ27940.1 - 0.0021 17.9 0.0 0.11 12.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ27940.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 OAJ27940.1 - 0.016 15.6 0.0 0.14 12.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ27940.1 - 0.029 14.8 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 OAJ27940.1 - 0.053 13.2 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 OAJ27940.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ27940.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 OAJ27940.1 - 0.075 13.3 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain Ribonuc_red_sm PF00268.21 OAJ27940.1 - 0.13 11.7 0.2 0.19 11.1 0.2 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain ATP_bind_3 PF01171.20 OAJ27941.1 - 1.2e-36 126.2 0.0 2.6e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 PP-loop family MMR_HSR1 PF01926.23 OAJ27941.1 - 4.1e-12 46.2 0.0 1.1e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ27941.1 - 0.00017 21.5 0.1 0.0082 16.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 OAJ27941.1 - 0.0029 18.0 1.8 0.025 15.0 0.1 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 OAJ27941.1 - 0.013 16.1 0.1 0.04 14.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OAJ27941.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.6 OAJ27941.1 - 0.064 13.5 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ThiC-associated PF13667.6 OAJ27941.1 - 0.1 12.5 0.3 0.7 9.8 0.1 2.3 2 0 0 2 2 2 0 ThiC-associated domain NAD_synthase PF02540.17 OAJ27941.1 - 0.15 11.1 0.0 0.62 9.1 0.0 1.8 2 0 0 2 2 2 0 NAD synthase DUF4554 PF15091.6 OAJ27941.1 - 2.3 7.0 3.7 1.6 7.5 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) Amino_oxidase PF01593.24 OAJ27942.1 - 1.1e-17 64.6 0.4 1.6e-16 60.6 0.4 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ27942.1 - 2.7e-13 49.9 0.1 6.5e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ27942.1 - 1.7e-05 24.6 1.1 1.7e-05 24.6 1.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ27942.1 - 0.00015 21.0 0.5 0.00015 21.0 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 OAJ27942.1 - 0.0015 18.5 0.1 0.036 14.0 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ27942.1 - 0.0031 16.8 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ27942.1 - 0.028 15.0 0.3 0.058 14.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ27942.1 - 0.19 10.9 0.1 0.38 9.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ27942.1 - 0.2 10.9 0.1 0.35 10.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ27942.1 - 0.27 9.9 0.2 0.41 9.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 OAJ27942.1 - 0.8 8.7 1.6 1.2 8.1 1.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.25 OAJ27943.1 - 5.1e-50 169.7 0.5 6.3e-50 169.4 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ27943.1 - 7.5e-35 120.6 0.2 9.5e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ27943.1 - 1e-14 54.9 0.2 1.3e-14 54.5 0.2 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 OAJ27943.1 - 0.0015 18.0 0.1 0.0035 16.7 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 OAJ27943.1 - 0.0015 18.0 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 OAJ27943.1 - 0.0066 15.9 0.1 0.0091 15.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 OAJ27943.1 - 0.009 15.9 0.5 0.016 15.1 0.5 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 OAJ27943.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 OAJ27943.1 - 0.057 12.7 0.2 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RNA12 PF10443.9 OAJ27944.1 - 1.1e-127 426.5 0.5 1.6e-127 425.9 0.5 1.3 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 OAJ27944.1 - 0.0027 17.6 0.0 0.0064 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea CENP-F_leu_zip PF10473.9 OAJ27944.1 - 0.43 10.6 3.7 0.17 11.9 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UCH PF00443.29 OAJ27946.1 - 6e-30 104.6 0.0 1.6e-29 103.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ27946.1 - 3.2e-11 43.4 0.0 5.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 OAJ27946.1 - 0.0034 17.0 0.2 0.016 14.9 0.0 2.1 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase MutS_V PF00488.21 OAJ27947.1 - 9.5e-60 201.8 0.1 2.5e-58 197.2 0.1 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ27947.1 - 2e-35 122.8 0.9 3.9e-35 121.8 0.9 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ27947.1 - 4.2e-24 85.0 0.0 1.4e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 OAJ27947.1 - 7.8e-10 39.2 0.0 1.8e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 OAJ27947.1 - 9.9e-09 35.4 0.0 2.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV zf_CCCH_4 PF18345.1 OAJ27948.1 - 0.00011 22.1 5.2 0.00019 21.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ27948.1 - 0.0019 17.9 2.9 0.0033 17.2 2.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 OAJ27948.1 - 0.015 15.2 2.0 0.028 14.4 2.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_carr PF00153.27 OAJ27949.1 - 5e-48 161.0 9.0 2.3e-16 59.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein K_channel_TID PF07941.11 OAJ27949.1 - 0.075 13.5 0.3 0.075 13.5 0.3 2.4 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Macoilin PF09726.9 OAJ27950.1 - 0.043 12.4 4.5 0.048 12.2 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Retrotrans_gag PF03732.17 OAJ27950.1 - 0.058 13.7 0.3 0.058 13.7 0.3 2.4 2 0 0 2 2 2 0 Retrotransposon gag protein TMF_DNA_bd PF12329.8 OAJ27950.1 - 4.4 7.4 15.4 1.3 9.1 9.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cyclin PF08613.11 OAJ27951.1 - 5.3e-37 127.7 2.8 1.8e-22 80.4 0.0 3.0 3 1 0 3 3 3 2 Cyclin DUF4834 PF16118.5 OAJ27951.1 - 0.81 10.7 3.2 5.9 7.9 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF2183 PF09949.9 OAJ27953.1 - 3.3e-25 88.3 0.0 6.1e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 OAJ27953.1 - 0.0019 17.7 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) AAA PF00004.29 OAJ27954.1 - 3.3e-40 137.5 0.1 9.3e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ27954.1 - 8.1e-19 67.3 0.0 1.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ27954.1 - 2.2e-09 37.0 0.3 5.6e-09 35.7 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ27954.1 - 2.1e-05 24.9 0.2 0.021 15.2 0.0 2.7 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 OAJ27954.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ27954.1 - 0.0013 19.0 0.4 0.065 13.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 OAJ27954.1 - 0.0013 18.7 0.7 0.0092 16.0 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 OAJ27954.1 - 0.0019 17.7 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_2 PF07724.14 OAJ27954.1 - 0.0019 18.3 2.2 0.0086 16.2 0.0 2.7 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 OAJ27954.1 - 0.006 16.4 0.9 0.32 10.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ27954.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 OAJ27954.1 - 0.014 14.7 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CENP-H PF05837.12 OAJ27954.1 - 0.027 14.9 0.8 0.073 13.5 0.8 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) IstB_IS21 PF01695.17 OAJ27954.1 - 0.03 14.1 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 OAJ27954.1 - 0.059 13.1 0.1 0.17 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 OAJ27954.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 OAJ27954.1 - 0.095 13.0 0.0 0.4 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAJ27954.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ribosomal_S19 PF00203.21 OAJ27954.1 - 0.16 11.9 0.1 22 5.0 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S19 G-gamma PF00631.22 OAJ27955.1 - 2.1e-21 75.7 0.0 2.3e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain CBFD_NFYB_HMF PF00808.23 OAJ27956.1 - 2.8e-15 56.3 0.3 5e-15 55.5 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ27956.1 - 1.4e-12 48.1 1.4 3.9e-12 46.7 1.4 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 OAJ27956.1 - 0.058 13.1 1.7 0.064 13.0 0.6 1.6 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family BUD22 PF09073.10 OAJ27958.1 - 1.2 8.3 21.3 1.3 8.2 21.3 1.0 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 OAJ27958.1 - 2.9 7.0 29.9 1.3 8.1 20.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.12 OAJ27958.1 - 3.5 5.5 6.8 4.1 5.3 6.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pox_Ag35 PF03286.14 OAJ27958.1 - 7.3 6.3 18.4 1.5 8.5 11.1 2.0 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Kelch_4 PF13418.6 OAJ27959.1 - 3e-28 97.6 15.7 2.9e-08 33.6 0.1 7.0 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ27959.1 - 7.8e-26 89.8 21.6 1.7e-08 34.5 0.3 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 OAJ27959.1 - 3.7e-23 81.0 7.6 1.3e-06 28.2 0.0 6.0 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 OAJ27959.1 - 6.1e-21 74.3 0.7 6.1e-21 74.3 0.7 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 OAJ27959.1 - 2.9e-19 68.6 11.0 4.2e-06 26.9 0.1 6.1 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 OAJ27959.1 - 3.9e-14 51.9 6.2 4.4e-06 26.2 0.0 5.7 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 OAJ27959.1 - 1.9e-11 43.5 3.2 0.00029 20.7 0.0 5.5 5 1 0 5 5 5 3 Kelch motif Gpr1_Fun34_YaaH PF01184.19 OAJ27961.1 - 1.8e-27 96.3 13.8 2.4e-27 95.9 13.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ycf4 PF02392.16 OAJ27961.1 - 2.6 7.6 4.5 0.49 10.0 0.5 1.8 2 0 0 2 2 2 0 Ycf4 Ribosomal_L34e PF01199.18 OAJ27962.1 - 2.2e-43 146.4 3.5 2.9e-43 146.1 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 OAJ27962.1 - 0.0093 15.9 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c7 and related cytochrome c FhuF_C PF11575.8 OAJ27962.1 - 0.028 14.3 2.1 3.9 7.5 0.2 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF2199 PF09965.9 OAJ27962.1 - 0.046 13.8 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Lactamase_B_2 PF12706.7 OAJ27963.1 - 7.1e-22 77.9 0.0 1.7e-15 57.1 0.0 3.4 3 0 0 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 OAJ27963.1 - 2.5e-06 27.5 0.0 5.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DAGK_cat PF00781.24 OAJ27964.1 - 1.5e-21 76.3 0.1 3.1e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Asparaginase_2 PF01112.18 OAJ27965.1 - 1.5 7.7 5.7 0.19 10.8 1.6 1.5 2 0 0 2 2 2 0 Asparaginase Endostatin PF06482.11 OAJ27965.1 - 2.3 7.6 18.5 0.23 10.9 8.5 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Maf1 PF09174.10 OAJ27965.1 - 3.9 7.6 11.6 0.39 10.9 5.5 2.1 2 0 0 2 2 2 0 Maf1 regulator MGC-24 PF05283.11 OAJ27965.1 - 4.5 7.7 12.0 12 6.3 0.5 2.5 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Membralin PF09746.9 OAJ27965.1 - 5.1 6.0 9.9 0.52 9.3 3.8 1.9 2 0 0 2 2 2 0 Tumour-associated protein TFIIF_alpha PF05793.12 OAJ27966.1 - 0.00048 18.9 0.0 0.00048 18.9 0.0 5.2 4 1 0 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) rve PF00665.26 OAJ27968.1 - 0.0017 18.6 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.6 OAJ27968.1 - 0.035 13.9 0.1 0.1 12.4 0.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain Aldo_ket_red PF00248.21 OAJ27970.1 - 1.1e-69 234.9 0.0 1.3e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_1 PF00561.20 OAJ27971.1 - 6.8e-21 75.1 0.0 5.1e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ27971.1 - 2.5e-14 54.4 1.8 2.5e-14 54.4 1.8 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ27971.1 - 8e-09 35.1 0.0 2.9e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 OAJ27971.1 - 2.9e-06 27.2 1.6 1.9e-05 24.6 0.0 2.8 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Esterase PF00756.20 OAJ27971.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 OAJ27971.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase F-box PF00646.33 OAJ27972.1 - 5.8e-10 38.8 0.9 1.4e-09 37.6 0.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ27972.1 - 0.0021 17.9 0.2 0.0051 16.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 OAJ27972.1 - 0.014 15.3 0.1 0.028 14.4 0.0 1.6 2 0 0 2 2 2 0 F-box-like domain F-box_4 PF15966.5 OAJ27972.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 F-box Pex14_N PF04695.13 OAJ27974.1 - 0.045 14.4 7.8 0.072 13.7 0.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RINT1_TIP1 PF04437.13 OAJ27975.1 - 8.7e-60 203.0 0.0 3.6e-58 197.7 0.0 3.1 1 1 0 1 1 1 1 RINT-1 / TIP-1 family AFG1_ATPase PF03969.16 OAJ27976.1 - 1.9e-54 184.9 0.1 7.1e-40 137.0 0.0 4.0 3 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 OAJ27976.1 - 1.4e-08 35.3 1.4 6.1e-08 33.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ27976.1 - 0.0002 21.4 0.0 0.043 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ27976.1 - 0.00022 21.5 0.0 0.0072 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SR-25 PF10500.9 OAJ27976.1 - 0.0015 18.2 7.7 0.0015 18.2 7.7 2.7 4 0 0 4 4 3 1 Nuclear RNA-splicing-associated protein AAA PF00004.29 OAJ27976.1 - 0.0016 18.8 0.0 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 OAJ27976.1 - 0.0021 18.4 0.0 1 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 OAJ27976.1 - 0.0071 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 OAJ27976.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 OAJ27976.1 - 0.093 12.5 0.1 0.94 9.2 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF4224 PF13986.6 OAJ27976.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) TIP49 PF06068.13 OAJ27976.1 - 0.27 10.4 0.0 18 4.4 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain AF-4 PF05110.13 OAJ27976.1 - 1.1 7.3 10.8 1.7 6.6 10.8 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3446 PF11928.8 OAJ27976.1 - 7.9 6.9 28.4 5.7 7.3 13.9 3.7 3 0 0 3 3 3 0 Early growth response N-terminal domain Methyltransf_11 PF08241.12 OAJ27977.1 - 1.9e-09 38.1 0.0 3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ27977.1 - 2.7e-08 34.4 0.1 5.1e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ27977.1 - 1.1e-05 25.4 0.0 1.2e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ27977.1 - 0.0014 19.3 0.0 0.0049 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ27977.1 - 0.0041 16.9 0.0 0.0063 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 OAJ27977.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCDHK_Adom3 PF10436.9 OAJ27978.1 - 2.6e-40 137.9 0.0 3.8e-40 137.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ27978.1 - 2.3e-09 37.7 0.0 4.1e-05 24.1 0.0 2.5 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ27978.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 OAJ27979.1 - 0.0083 16.0 2.6 0.009 15.9 0.5 2.2 2 0 0 2 2 2 1 F-box-like DDE_3 PF13358.6 OAJ27984.1 - 1.3e-26 93.1 0.0 2.1e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ27984.1 - 4.2e-07 29.5 0.1 1.6e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ27984.1 - 1.3e-05 25.7 9.7 0.0066 17.0 0.0 2.8 3 0 0 3 3 3 2 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ27984.1 - 4e-05 22.7 0.1 0.0051 15.8 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain rve PF00665.26 OAJ27984.1 - 0.0022 18.2 0.0 0.0059 16.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HECT PF00632.25 OAJ27985.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF3915 PF13054.6 OAJ27986.1 - 0.13 12.2 3.4 0.26 11.3 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DAHP_synth_1 PF00793.20 OAJ27987.1 - 1.2e-98 329.3 0.0 1.5e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AMP-binding PF00501.28 OAJ27988.1 - 3.8e-70 236.6 0.0 4.8e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ27988.1 - 3.1e-11 44.1 0.5 7.4e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GATA PF00320.27 OAJ27989.1 - 2.4e-12 46.2 12.5 6.5e-07 28.9 3.5 2.4 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 OAJ27989.1 - 0.00024 21.2 0.7 0.18 12.0 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Vps36-NZF-N PF16988.5 OAJ27989.1 - 0.068 12.6 4.8 3.5 7.1 0.5 3.4 2 2 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TF_Zn_Ribbon PF08271.12 OAJ27989.1 - 4.6 6.8 11.3 2.2 7.9 0.3 3.1 3 1 0 3 3 3 0 TFIIB zinc-binding RhoGEF PF00621.20 OAJ27990.1 - 6.9e-28 98.1 0.2 1.1e-27 97.4 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain SpoIIIAH PF12685.7 OAJ27990.1 - 0.2 11.5 2.2 9.5 6.0 0.0 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein PRIMA1 PF16101.5 OAJ27990.1 - 5.4 7.1 13.8 0.034 14.2 1.3 3.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 TRAPP PF04051.16 OAJ27991.1 - 4.2e-40 136.8 0.0 5e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component eIF3_N PF09440.10 OAJ27992.1 - 2.1e-40 138.3 2.0 4.4e-40 137.2 0.5 2.1 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 OAJ27992.1 - 3.3e-10 40.4 0.1 6.6e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.6 OAJ27992.1 - 0.036 14.3 0.3 1.4 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ27992.1 - 0.86 9.9 3.8 4.5 7.6 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Matrilin_ccoil PF10393.9 OAJ27993.1 - 0.037 13.9 0.1 0.058 13.3 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.12 OAJ27993.1 - 0.054 14.0 0.1 0.07 13.6 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Collagen PF01391.18 OAJ27994.1 - 0.0002 21.1 17.3 0.0002 21.1 17.3 3.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Solute_trans_a PF03619.16 OAJ27996.1 - 0.038 13.5 0.1 0.038 13.5 0.1 1.7 2 0 0 2 2 2 0 Organic solute transporter Ostalpha BB_PF PF18063.1 OAJ27999.1 - 0.2 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Beta barrel Pore-forming domain Serglycin PF04360.12 OAJ27999.1 - 1.6 8.6 9.8 4.3 7.3 5.6 2.6 2 0 0 2 2 2 0 Serglycin EBP50_C PF09007.11 OAJ28000.1 - 0.033 15.2 0.7 0.048 14.7 0.7 1.3 1 0 0 1 1 1 0 EBP50, C-terminal FA_desaturase PF00487.24 OAJ28000.1 - 0.067 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase stn_TNFRSF12A PF12191.8 OAJ28000.1 - 0.13 12.4 0.5 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF2933 PF11666.8 OAJ28000.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2933) CFEM PF05730.11 OAJ28000.1 - 0.32 11.1 5.7 0.52 10.4 5.0 1.8 1 1 0 1 1 1 0 CFEM domain GPI-anchored PF10342.9 OAJ28001.1 - 3.6e-05 24.5 2.6 4.5e-05 24.1 2.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CarbpepA_inh PF02977.15 OAJ28003.1 - 0.03 14.1 1.7 0.03 14.1 1.7 1.8 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor Hydrophobin PF01185.18 OAJ28003.1 - 0.049 14.3 1.0 0.049 14.3 1.0 2.0 1 1 1 2 2 2 0 Fungal hydrophobin zf-AN1 PF01428.16 OAJ28004.1 - 1.2e-15 57.4 20.5 4.7e-11 42.7 5.4 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 OAJ28004.1 - 0.00031 21.0 13.1 0.039 14.3 2.8 3.2 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 OAJ28004.1 - 0.004 17.3 9.7 0.027 14.7 0.3 2.7 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.12 OAJ28004.1 - 0.16 12.3 8.6 0.97 9.7 0.3 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-CRD PF17979.1 OAJ28004.1 - 3.2 7.8 8.6 2.2 8.4 3.2 2.2 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions RCC1 PF00415.18 OAJ28005.1 - 6.1e-23 81.2 3.2 5e-05 23.8 0.0 7.2 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ28005.1 - 2.1e-15 56.1 11.1 8.1e-05 22.3 0.1 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 OAJ28005.1 - 0.02 15.1 0.2 0.17 12.1 0.0 2.8 2 1 0 2 2 2 0 Putative heavy-metal chelation Helicase_C PF00271.31 OAJ28006.1 - 1.4e-22 80.1 0.1 6.6e-22 78.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ28006.1 - 7.8e-21 74.8 0.0 2e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ28006.1 - 2.1e-15 56.9 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 OAJ28006.1 - 0.00091 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF4913 PF16259.5 OAJ28007.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) UDPGT PF00201.18 OAJ28008.1 - 2.5e-12 46.3 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase SpoIIE PF07228.12 OAJ28010.1 - 1.3e-07 31.7 0.0 0.034 14.1 0.0 3.3 3 0 0 3 3 3 3 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 OAJ28010.1 - 1.1e-05 25.2 1.0 0.013 15.2 0.1 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.21 OAJ28010.1 - 5.9e-05 22.8 0.0 0.00069 19.3 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C PPR_2 PF13041.6 OAJ28011.1 - 1.6e-27 95.4 0.1 1e-07 32.0 0.0 8.0 6 2 3 9 9 9 6 PPR repeat family PPR PF01535.20 OAJ28011.1 - 6.3e-20 70.0 4.0 0.014 15.6 0.0 9.2 12 1 0 12 12 12 4 PPR repeat PPR_3 PF13812.6 OAJ28011.1 - 1.5e-16 60.2 0.0 1.5e-06 28.2 0.0 7.2 4 1 4 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 OAJ28011.1 - 1.3e-12 47.2 0.1 0.00031 20.4 0.0 6.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 OAJ28011.1 - 5.2e-09 35.8 0.0 7.1e-08 32.1 0.0 2.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 OAJ28011.1 - 0.0004 21.0 10.8 4.5 8.3 0.0 7.6 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ28011.1 - 0.0025 17.7 0.0 2.6 8.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat GTP_EFTU PF00009.27 OAJ28012.1 - 3.4e-42 144.2 0.1 6.4e-42 143.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ28012.1 - 2.1e-37 127.6 0.1 8.4e-37 125.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 OAJ28012.1 - 2e-29 101.5 0.0 4.6e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 OAJ28012.1 - 9.8e-23 80.0 0.2 2.5e-22 78.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ28012.1 - 4.2e-12 46.3 0.0 1.1e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ28012.1 - 8e-07 28.9 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain HlyE PF06109.13 OAJ28013.1 - 0.16 11.2 1.8 0.43 9.8 0.2 1.9 1 1 1 2 2 2 0 Haemolysin E (HlyE) Usp PF00582.26 OAJ28014.1 - 0.00063 20.3 4.0 0.13 12.8 0.1 3.7 3 0 0 3 3 3 2 Universal stress protein family RuvX PF03652.15 OAJ28014.1 - 0.018 15.5 0.5 0.16 12.4 0.0 2.7 3 0 0 3 3 3 0 Holliday junction resolvase Fungal_trans PF04082.18 OAJ28015.1 - 8e-11 41.5 0.0 1.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2 PF00096.26 OAJ28015.1 - 0.00043 20.6 5.9 0.072 13.6 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ28015.1 - 0.28 12.1 14.2 0.18 12.7 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Serglycin PF04360.12 OAJ28015.1 - 4.3 7.3 13.1 0.021 14.8 1.4 2.7 2 0 0 2 2 2 0 Serglycin Thi4 PF01946.17 OAJ28017.1 - 2.1e-13 50.1 0.0 2.4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Thi4 family TPR_12 PF13424.6 OAJ28018.1 - 9.8e-05 22.6 10.9 0.046 14.0 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ28018.1 - 0.025 15.1 1.2 0.09 13.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ28018.1 - 0.03 14.5 0.0 19 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ28018.1 - 0.035 14.0 1.2 9.2 6.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Gpr1_Fun34_YaaH PF01184.19 OAJ28018.1 - 0.17 11.5 0.6 0.27 10.8 0.6 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family TPR_2 PF07719.17 OAJ28018.1 - 0.18 12.0 1.2 17 5.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 OAJ28019.1 - 6.5e-08 32.3 12.4 8.5e-08 31.9 9.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ28019.1 - 9.6e-07 28.7 14.1 4.8e-06 26.5 9.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ28019.1 - 1.5e-06 28.0 9.2 1.5e-06 28.0 9.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ28019.1 - 1.7e-06 27.8 3.9 3.6e-06 26.7 3.1 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ28019.1 - 6e-06 26.3 9.2 6e-06 26.3 9.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ28019.1 - 1.6e-05 24.7 13.8 3.6e-05 23.6 10.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ28019.1 - 5e-05 23.3 4.9 0.00013 21.9 3.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SAP PF02037.27 OAJ28019.1 - 6.3e-05 22.6 0.8 0.00023 20.8 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-C3HC4_3 PF13920.6 OAJ28019.1 - 6.3e-05 22.7 11.6 0.00071 19.4 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ28019.1 - 0.00014 22.1 15.6 0.00031 21.0 10.1 2.3 2 0 0 2 2 2 1 Ring finger domain Serglycin PF04360.12 OAJ28019.1 - 0.003 17.5 1.1 0.0071 16.3 1.1 1.6 1 0 0 1 1 1 1 Serglycin zf-Nse PF11789.8 OAJ28019.1 - 0.0058 16.4 4.4 0.0058 16.4 4.4 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_5 PF13719.6 OAJ28019.1 - 0.0071 16.1 0.3 2.9 7.7 0.1 3.3 3 0 0 3 3 3 1 zinc-ribbon domain Prok-RING_4 PF14447.6 OAJ28019.1 - 0.012 15.5 11.2 1.4 8.8 7.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ28019.1 - 0.11 12.8 10.1 0.068 13.5 5.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAJ28019.1 - 1.2 9.3 6.0 2.7 8.2 6.0 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 OAJ28019.1 - 1.3 9.2 10.4 8.2 6.7 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.6 OAJ28019.1 - 1.3 8.9 11.3 3.3 7.6 8.8 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_4 PF13894.6 OAJ28019.1 - 1.3 10.0 0.0 1.3 10.0 0.0 3.9 3 1 1 4 4 2 0 C2H2-type zinc finger Pex2_Pex12 PF04757.14 OAJ28021.1 - 2e-28 99.6 6.5 2.6e-28 99.2 6.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 OAJ28021.1 - 1.1e-09 38.5 8.1 1.6e-09 37.9 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 OAJ28021.1 - 1e-08 34.9 4.7 1.6e-08 34.3 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ28021.1 - 1.9e-08 34.1 6.0 3e-08 33.5 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ28021.1 - 5.6e-08 32.5 6.7 1e-07 31.7 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ28021.1 - 1.4e-07 31.3 4.8 2.2e-07 30.6 4.8 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 OAJ28021.1 - 2.2e-07 31.0 5.3 4.1e-07 30.2 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 OAJ28021.1 - 3.1e-07 30.3 2.2 8.7e-07 28.9 2.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ28021.1 - 5.2e-07 29.4 6.1 8.4e-07 28.8 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ28021.1 - 0.00073 19.6 3.1 0.00073 19.6 3.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 OAJ28021.1 - 0.014 15.2 6.6 0.023 14.5 6.6 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 OAJ28021.1 - 0.036 14.1 2.3 0.074 13.1 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ28021.1 - 0.039 13.7 3.3 0.042 13.6 1.7 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 OAJ28021.1 - 0.043 14.0 4.4 0.08 13.1 4.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 OAJ28021.1 - 0.063 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 OAJ28021.1 - 0.11 12.4 2.3 0.2 11.5 2.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 OAJ28021.1 - 0.14 12.4 4.7 0.28 11.5 4.7 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Btz PF09405.10 OAJ28022.1 - 3.4e-05 24.1 0.0 3.4e-05 24.1 0.0 4.6 4 1 1 5 5 5 2 CASC3/Barentsz eIF4AIII binding SDA1 PF05285.12 OAJ28022.1 - 1.1 8.7 24.8 1.9 7.9 24.8 1.3 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 OAJ28022.1 - 2.4 7.4 17.3 5 6.4 17.3 1.4 1 0 0 1 1 1 0 NOA36 protein GOLD_2 PF13897.6 OAJ28022.1 - 4.4 7.8 5.7 11 6.5 5.7 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sec15 PF04091.12 OAJ28023.1 - 0.029 13.8 2.0 0.097 12.1 0.0 2.4 3 0 0 3 3 3 0 Exocyst complex subunit Sec15-like REV1_C PF16727.5 OAJ28023.1 - 0.03 14.7 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain DUF3295 PF11702.8 OAJ28024.1 - 7e-12 45.5 1.9 7e-12 45.5 1.9 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF3295) SDA1 PF05285.12 OAJ28024.1 - 4 6.8 16.7 6.7 6.0 16.5 1.4 1 1 0 1 1 1 0 SDA1 EPL1 PF10513.9 OAJ28025.1 - 1e-18 68.2 0.0 1e-18 68.2 0.0 5.0 4 1 0 4 4 4 2 Enhancer of polycomb-like Pro_isomerase PF00160.21 OAJ28026.1 - 3.4e-45 154.2 0.1 6.4e-45 153.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Xpo1 PF08389.12 OAJ28026.1 - 8e-15 55.2 0.0 7.6e-14 52.0 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 OAJ28026.1 - 0.00088 19.6 0.3 0.0047 17.3 0.3 2.3 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 OAJ28026.1 - 0.024 14.9 0.1 0.4 11.1 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.23 OAJ28026.1 - 0.12 12.4 0.1 0.71 10.0 0.1 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MULE PF10551.9 OAJ28027.1 - 5.2e-22 78.1 0.4 1.3e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ28027.1 - 1.1e-07 31.1 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DUF4449 PF14613.6 OAJ28028.1 - 2.2e-34 118.9 1.4 2.2e-34 118.9 1.4 3.6 3 1 0 4 4 4 1 Protein of unknown function (DUF4449) Endotoxin_N PF03945.14 OAJ28028.1 - 0.04 13.6 2.2 0.051 13.3 0.5 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain pPIWI_RE_Z PF18155.1 OAJ28028.1 - 0.11 12.3 0.2 0.37 10.6 0.2 1.9 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Lsr2 PF11774.8 OAJ28028.1 - 4.3 7.5 8.0 2.3 8.4 0.2 3.5 3 0 0 3 3 3 0 Lsr2 UPF0029 PF01205.19 OAJ28030.1 - 6.9e-19 68.1 0.0 2.1e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Con-6 PF10346.9 OAJ28031.1 - 4.7e-09 36.1 0.3 1e-08 35.1 0.3 1.5 1 0 0 1 1 1 1 Conidiation protein 6 UQ_con PF00179.26 OAJ28032.1 - 2.3e-21 75.9 0.0 3.5e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ28032.1 - 0.065 13.1 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 UEV domain HALZ PF02183.18 OAJ28034.1 - 0.0026 17.9 0.3 0.0038 17.4 0.3 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper Herpes_UL69 PF05459.12 OAJ28035.1 - 0.018 14.4 1.0 0.023 14.0 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family ROF PF07073.12 OAJ28035.1 - 0.04 14.1 0.7 0.094 12.9 0.7 1.6 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) MFS_1 PF07690.16 OAJ28037.1 - 6.5e-42 143.7 49.8 6.5e-42 143.7 49.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ28037.1 - 2.9e-15 55.7 20.6 3.6e-15 55.4 20.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ28037.1 - 1.2e-11 44.2 10.3 1.2e-11 44.2 10.3 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter MRAP PF15183.6 OAJ28037.1 - 0.48 10.4 0.1 0.48 10.4 0.1 2.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family HCV_NS4a PF01006.20 OAJ28037.1 - 2.6 7.9 5.7 1.3 8.8 1.7 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a DUF3930 PF13067.6 OAJ28037.1 - 4.6 7.6 5.2 1.7 8.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) SHR3_chaperone PF08229.11 OAJ28038.1 - 0.15 11.0 0.0 0.18 10.8 0.0 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 Glyco_hydro_5_C PF18564.1 OAJ28039.1 - 2.4e-08 34.4 0.0 6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ28039.1 - 0.00015 21.3 0.0 0.34 10.3 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) ATP-synt_ab PF00006.25 OAJ28039.1 - 0.00065 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain UPF0061 PF02696.14 OAJ28040.1 - 8.6e-06 24.8 0.1 1.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF1729 PF08354.10 OAJ28041.1 - 4.3e-36 124.6 0.0 5.9e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Glyco_hydro_30 PF02055.16 OAJ28044.1 - 3e-18 65.9 0.6 2.3e-17 63.0 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 OAJ28044.1 - 1.6e-05 24.3 0.1 3.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_tranf_2_3 PF13641.6 OAJ28047.1 - 2.8e-20 73.2 0.0 3.9e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ28047.1 - 1.1e-16 61.3 4.6 1.1e-16 61.3 4.6 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 OAJ28047.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 OAJ28047.1 - 3.2e-07 30.3 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Gate PF07670.14 OAJ28047.1 - 0.035 14.4 2.7 0.076 13.3 2.7 1.6 1 0 0 1 1 1 0 Nucleoside recognition Helitron_like_N PF14214.6 OAJ28049.1 - 9.2e-18 65.1 0.0 2.9e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 OAJ28049.1 - 1.2e-17 64.2 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 OAJ28049.1 - 8.3e-15 55.0 0.2 8.3e-15 55.0 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 OAJ28049.1 - 1.1e-10 42.1 0.0 2.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ28049.1 - 0.0028 18.1 0.3 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ28049.1 - 0.0087 16.3 0.0 0.035 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 OAJ28049.1 - 0.01 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Helicase ResIII PF04851.15 OAJ28049.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 OAJ28049.1 - 0.093 12.7 0.3 0.68 9.9 0.3 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 OAJ28049.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Torsin Osteopontin PF00865.18 OAJ28049.1 - 0.25 10.8 10.2 0.62 9.5 10.2 1.6 1 0 0 1 1 1 0 Osteopontin Pkinase PF00069.25 OAJ28051.1 - 3.5e-47 161.0 0.0 7.2e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28051.1 - 7.8e-33 113.8 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ28051.1 - 1.5e-05 24.5 0.0 4.9e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ28051.1 - 0.0054 16.1 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Fez1 PF06818.15 OAJ28051.1 - 3.3 8.1 35.9 2.2 8.7 0.7 3.2 1 1 2 3 3 3 0 Fez1 Bcr-Abl_Oligo PF09036.10 OAJ28051.1 - 5.4 7.1 6.9 4.3 7.4 0.6 3.5 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain PKcGMP_CC PF16808.5 OAJ28051.1 - 6.1 6.8 8.3 4.5 7.2 0.1 4.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sortilin-Vps10 PF15902.5 OAJ28053.1 - 4e-135 451.1 0.0 4.9e-135 450.8 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 OAJ28053.1 - 2.6e-40 138.5 1.6 2.6e-40 138.5 1.6 1.6 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal CHB_HEX_C PF03174.13 OAJ28053.1 - 0.001 19.0 0.4 2 8.5 0.0 3.5 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain F5_F8_type_C PF00754.25 OAJ28053.1 - 0.066 13.3 1.0 4.2 7.5 0.0 4.0 6 0 0 6 6 6 0 F5/8 type C domain E1-E2_ATPase PF00122.20 OAJ28054.1 - 8.7e-27 93.8 0.0 2.6e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 OAJ28054.1 - 4.2e-26 91.5 0.0 5e-23 81.6 0.0 2.4 2 0 0 2 2 2 2 P5-type ATPase cation transporter Hydrolase PF00702.26 OAJ28054.1 - 1.4e-16 61.4 0.4 2.9e-08 34.3 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 OAJ28054.1 - 1.1e-06 28.5 10.0 2.8e-06 27.2 10.0 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 OAJ28054.1 - 8.5e-05 22.6 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 OAJ28054.1 - 0.0093 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus NAD_kinase PF01513.21 OAJ28055.1 - 7.4e-53 179.6 0.0 9.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 OAJ28055.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PIF1 PF05970.14 OAJ28056.1 - 2.8e-59 201.1 0.6 2.9e-46 158.3 0.1 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 OAJ28056.1 - 2.1e-22 79.8 0.0 3.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ28056.1 - 4.9e-12 46.4 0.0 8.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ28056.1 - 5.7e-06 26.7 0.0 1.9e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ28056.1 - 2.8e-05 23.7 0.1 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 OAJ28056.1 - 0.00051 19.8 0.1 0.57 9.9 0.1 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAJ28056.1 - 0.00075 19.3 0.5 0.0064 16.3 0.2 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 OAJ28056.1 - 0.0018 17.4 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 OAJ28056.1 - 0.0022 17.3 0.0 0.0043 16.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 OAJ28056.1 - 0.0033 17.8 0.1 0.0082 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAJ28056.1 - 0.0036 17.7 0.0 0.0077 16.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 OAJ28056.1 - 0.0072 15.3 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 OAJ28056.1 - 0.0097 15.8 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain SH3_13 PF18335.1 OAJ28056.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ATPase_2 PF01637.18 OAJ28056.1 - 0.034 14.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 OAJ28056.1 - 0.038 13.7 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 OAJ28056.1 - 0.038 13.4 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Herpes_Helicase PF02689.14 OAJ28056.1 - 0.046 11.7 0.1 0.49 8.2 0.0 2.1 2 0 0 2 2 2 0 Helicase NB-ARC PF00931.22 OAJ28056.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 OAJ28056.1 - 0.059 13.4 0.0 0.41 10.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ28056.1 - 0.066 12.6 0.1 0.28 10.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial TniB protein Sigma54_activat PF00158.26 OAJ28056.1 - 0.084 12.6 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 OAJ28056.1 - 0.092 12.6 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 OAJ28056.1 - 0.13 12.2 0.2 1.1 9.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 OAJ28056.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_trans_NIPA PF05653.14 OAJ28057.1 - 4.2e-92 308.4 26.9 5.7e-92 308.0 26.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 OAJ28057.1 - 0.00034 20.8 11.5 0.00034 20.8 11.5 3.6 2 2 1 3 3 3 1 EamA-like transporter family PP2C PF00481.21 OAJ28058.1 - 6.8e-48 163.5 0.1 1.3e-47 162.6 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 OAJ28058.1 - 2.8e-39 132.7 53.3 1.1e-08 34.7 3.0 9.6 4 2 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 OAJ28058.1 - 1.3e-33 114.4 65.5 9.1e-06 25.9 0.4 12.2 4 2 11 17 17 17 15 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 OAJ28058.1 - 1.1e-24 87.0 0.0 2.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 OAJ28058.1 - 0.0003 20.9 34.0 4.4 8.2 0.0 13.1 11 3 0 11 11 11 2 Leucine Rich Repeat LRR_9 PF14580.6 OAJ28058.1 - 0.032 13.7 17.8 0.022 14.3 1.5 4.2 2 1 3 5 5 5 0 Leucine-rich repeat COesterase PF00135.28 OAJ28059.1 - 8.6e-87 292.1 0.0 1e-86 291.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ28059.1 - 0.00039 20.3 0.1 0.00078 19.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ28059.1 - 0.01 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SMN PF06003.12 OAJ28060.1 - 2.7 7.2 4.3 5.3 6.2 4.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mito_fiss_reg PF05308.11 OAJ28060.1 - 3.7 7.5 5.7 0.39 10.8 1.5 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 OAJ28061.1 - 2.4e-18 66.5 0.0 2e-15 56.9 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28061.1 - 1.5e-05 24.4 0.0 0.0008 18.8 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 OAJ28061.1 - 0.0021 18.0 0.9 0.0037 17.2 0.3 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Alanine_zipper PF11839.8 OAJ28061.1 - 4.9 7.6 12.2 0.29 11.5 1.2 3.3 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein zf-C3HC4 PF00097.25 OAJ28062.1 - 8.6e-06 25.5 2.3 3.3e-05 23.7 0.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ28062.1 - 0.00056 19.9 1.2 0.0014 18.6 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Torus PF16131.5 OAJ28062.1 - 0.00065 20.4 4.4 0.0025 18.5 0.1 2.7 2 1 0 2 2 2 1 Torus domain zf-RING_2 PF13639.6 OAJ28062.1 - 0.0011 19.3 0.6 0.0011 19.3 0.6 3.3 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ28062.1 - 0.0094 15.8 0.6 0.0094 15.8 0.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ28062.1 - 0.041 13.9 2.3 0.18 11.8 0.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ28062.1 - 0.06 13.2 4.3 0.78 9.7 1.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 OAJ28062.1 - 0.075 13.1 16.7 0.13 12.4 5.7 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-C3HC4_3 PF13920.6 OAJ28062.1 - 0.12 12.3 7.3 0.1 12.4 0.5 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 OAJ28062.1 - 0.34 10.8 13.4 0.43 10.4 5.7 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-rbx1 PF12678.7 OAJ28062.1 - 0.37 11.1 3.1 2.5 8.5 0.3 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 OAJ28062.1 - 0.63 10.6 15.7 1.6 9.3 7.1 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-RING_11 PF17123.5 OAJ28062.1 - 1.2 9.0 5.4 0.53 10.1 3.0 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-CCCH PF00642.24 OAJ28062.1 - 3.2 7.8 9.7 22 5.1 5.0 2.7 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3778 PF12620.8 OAJ28063.1 - 0.082 12.5 1.0 1.2 8.8 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) EPL1 PF10513.9 OAJ28063.1 - 3.4 8.0 10.3 0.36 11.2 4.4 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like SIP1 PF04938.12 OAJ28064.1 - 1.8e-25 90.0 0.1 3.4e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) zf-C3HC4_3 PF13920.6 OAJ28065.1 - 0.001 18.8 7.2 0.0023 17.7 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ28065.1 - 0.64 10.0 9.4 1.4 8.9 9.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ28065.1 - 4.9 7.3 7.1 11 6.2 7.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ28065.1 - 5 7.1 10.4 11 5.9 10.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ28065.1 - 6.5 7.2 9.7 15 6.1 9.7 1.6 1 0 0 1 1 1 0 Ring finger domain MAS20 PF02064.15 OAJ28066.1 - 9.1e-24 84.0 0.2 1.3e-23 83.5 0.2 1.2 1 0 0 1 1 1 1 MAS20 protein import receptor FUSC PF04632.12 OAJ28066.1 - 0.23 9.9 6.2 0.32 9.5 6.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Myosin_head PF00063.21 OAJ28067.1 - 5.8e-265 880.7 0.0 1.3e-264 879.5 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 OAJ28067.1 - 2e-07 30.7 0.4 4.8e-07 29.5 0.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.6 OAJ28067.1 - 0.1 12.9 0.1 0.1 12.9 0.1 3.3 3 2 0 3 3 3 0 AAA domain AAA_22 PF13401.6 OAJ28067.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.5 3 1 1 4 4 4 0 AAA domain IQ PF00612.27 OAJ28067.1 - 0.26 11.2 2.8 0.38 10.7 0.5 2.4 2 0 0 2 2 2 0 IQ calmodulin-binding motif Sec20 PF03908.13 OAJ28068.1 - 5.5e-19 67.9 1.3 1.3e-18 66.7 1.3 1.6 1 0 0 1 1 1 1 Sec20 DAHP_synth_1 PF00793.20 OAJ28069.1 - 1e-99 332.9 0.0 1.2e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Aminotran_5 PF00266.19 OAJ28070.1 - 9.3e-29 100.5 0.0 1.5e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 OAJ28070.1 - 0.0066 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 B12 binding domain RVT_2 PF07727.14 OAJ28072.1 - 4.7e-63 213.0 0.0 7.1e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ28072.1 - 3.8e-15 56.1 0.1 3e-14 53.2 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ28072.1 - 2.6e-07 30.4 0.0 4.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ28072.1 - 0.00031 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SPC25 PF06703.11 OAJ28073.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Retrotran_gag_2 PF14223.6 OAJ28074.1 - 3.1e-23 82.0 0.2 4.5e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type OAF PF14941.6 OAJ28074.1 - 0.061 12.8 0.1 0.091 12.2 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first MIF4G_like PF09088.11 OAJ28076.1 - 2.6e-65 219.8 0.1 3.5e-64 216.1 0.0 2.6 3 0 0 3 3 3 1 MIF4G like MIF4G_like_2 PF09090.11 OAJ28076.1 - 9.1e-61 205.7 0.0 2.7e-60 204.1 0.0 1.9 1 1 0 1 1 1 1 MIF4G like DUF4407 PF14362.6 OAJ28076.1 - 0.53 9.6 4.6 1.1 8.6 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Myb_DNA-bind_3 PF12776.7 OAJ28077.1 - 7.1e-05 23.7 0.4 0.00013 22.8 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PRP38_assoc PF12871.7 OAJ28077.1 - 0.51 11.0 7.3 0.96 10.1 7.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Skp1 PF01466.19 OAJ28078.1 - 3.3e-27 94.3 0.3 3.3e-27 94.3 0.3 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 OAJ28078.1 - 2.3e-19 69.3 0.1 5.7e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Spt4 PF06093.13 OAJ28079.1 - 3.6e-29 100.7 0.1 4.1e-29 100.5 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Med11 PF10280.9 OAJ28080.1 - 1.7e-07 31.8 0.0 2.7e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Mediator complex protein zf-CCHC PF00098.23 OAJ28082.1 - 2.8e-05 24.0 5.1 6.3e-05 22.9 5.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ28082.1 - 0.0098 15.7 5.3 0.019 14.8 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ28082.1 - 0.037 14.0 1.5 0.069 13.1 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 OAJ28083.1 - 1.3e-69 234.5 0.0 2e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ28083.1 - 2.9e-18 66.2 0.0 7.4e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ28083.1 - 9.9e-06 25.2 0.1 2.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ28083.1 - 0.00086 19.1 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.25 OAJ28084.1 - 1.1e-68 231.5 0.0 1.3e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28084.1 - 1e-48 165.9 0.0 1.4e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ28084.1 - 2.1e-06 26.8 0.3 8.3e-06 24.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAJ28084.1 - 0.0026 17.1 0.0 0.0092 15.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PRP38_assoc PF12871.7 OAJ28084.1 - 0.025 15.2 1.1 0.025 15.2 1.1 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 OAJ28084.1 - 0.15 10.9 6.5 0.31 9.9 6.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 OAJ28084.1 - 0.33 10.5 10.2 0.81 9.2 10.2 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bromodomain PF00439.25 OAJ28086.1 - 5.6e-30 103.2 1.9 2e-13 50.2 0.1 3.5 3 1 0 3 3 3 2 Bromodomain BET PF17035.5 OAJ28086.1 - 2e-18 66.3 0.1 3.6e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation MAD PF05557.13 OAJ28087.1 - 0.47 8.7 16.9 0.014 13.8 10.0 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein HAUS-augmin3 PF14932.6 OAJ28087.1 - 0.85 9.1 5.2 2 7.9 4.4 2.0 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Abhydro_lipase PF04083.16 OAJ28088.1 - 1e-13 50.6 0.0 2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ28088.1 - 1.3e-06 28.2 0.3 2.1e-06 27.6 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ28088.1 - 0.00031 20.1 0.0 0.00049 19.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SRP68 PF16969.5 OAJ28089.1 - 3e-59 201.5 32.3 7.1e-49 167.3 13.4 3.6 3 1 0 3 3 3 2 RNA-binding signal recognition particle 68 DinB_2 PF12867.7 OAJ28090.1 - 0.0013 19.2 0.3 0.0022 18.5 0.3 1.4 1 0 0 1 1 1 1 DinB superfamily MDMPI_N PF11716.8 OAJ28090.1 - 0.0045 17.7 0.2 0.0075 17.0 0.2 1.3 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain ATP-synt_J PF04911.12 OAJ28091.1 - 1.2e-24 85.6 1.6 1.6e-24 85.2 1.6 1.2 1 0 0 1 1 1 1 ATP synthase j chain DASH_Dad3 PF08656.10 OAJ28092.1 - 5.3e-19 68.1 0.7 6.7e-19 67.8 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Forkhead PF00250.18 OAJ28093.1 - 5e-24 84.4 0.0 1.4e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Forkhead domain TFIIA PF03153.13 OAJ28093.1 - 0.0019 18.3 15.5 0.0019 18.3 15.5 2.3 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit eIF_4EBP PF05456.11 OAJ28093.1 - 0.018 15.0 1.1 0.018 15.0 1.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Spt20 PF12090.8 OAJ28093.1 - 0.65 9.6 26.0 1.4 8.4 26.0 1.5 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 OAJ28093.1 - 0.98 9.8 8.9 0.3 11.4 5.8 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like CCDC53 PF10152.9 OAJ28093.1 - 1.9 8.9 7.5 0.54 10.7 3.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Neur_chan_memb PF02932.16 OAJ28093.1 - 2.2 8.3 4.7 1.2 9.1 1.5 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.12 OAJ28093.1 - 3.3 6.6 9.6 5.8 5.8 9.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) API5 PF05918.11 OAJ28093.1 - 4 6.2 11.3 7.1 5.3 11.3 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AAA_9 PF12781.7 OAJ28094.1 - 1.9e-74 249.5 3.7 9.2e-74 247.3 0.1 3.3 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 OAJ28094.1 - 2.6e-46 158.3 4.8 4.9e-46 157.3 4.8 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 OAJ28094.1 - 4.8e-41 141.0 0.7 8.2e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 OAJ28094.1 - 2.7e-37 128.1 0.0 6.4e-37 126.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 OAJ28094.1 - 6.2e-29 100.5 0.0 1.3e-27 96.2 0.0 3.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 OAJ28094.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DUF948 PF06103.11 OAJ28094.1 - 0.59 10.4 8.4 14 6.0 0.7 4.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAJ28094.1 - 1.6 7.5 35.8 0.0096 14.8 12.0 3.8 4 0 0 4 4 4 0 Spc7 kinetochore protein LOH1CR12 PF10158.9 OAJ28094.1 - 2.4 8.2 7.1 0.51 10.4 0.5 2.9 3 0 0 3 3 3 0 Tumour suppressor protein Phlebovirus_NSM PF07246.11 OAJ28094.1 - 5.9 6.2 8.4 2.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Sugar_tr PF00083.24 OAJ28095.1 - 5.2e-72 243.1 8.7 4e-39 134.7 0.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ28095.1 - 5.8e-19 68.2 30.1 5.8e-19 68.2 30.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_16 PF10294.9 OAJ28096.1 - 4.7e-22 78.5 0.0 9.6e-10 38.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase AMP-binding PF00501.28 OAJ28097.1 - 4.4e-77 259.5 0.0 7.7e-77 258.7 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme DUF2462 PF09495.10 OAJ28098.1 - 1e-15 58.2 9.2 1e-15 58.2 9.2 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) DUF2868 PF11067.8 OAJ28098.1 - 0.33 10.4 2.9 0.35 10.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) RT_RNaseH PF17917.1 OAJ28099.1 - 4e-11 43.1 0.0 1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ28099.1 - 3.9e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TauD PF02668.16 OAJ28101.1 - 7.9e-43 147.2 0.1 1.6e-42 146.2 0.1 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RhoGAP PF00620.27 OAJ28103.1 - 4.3e-45 153.2 0.4 1.4e-44 151.6 0.0 2.1 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 OAJ28103.1 - 3.4e-12 46.4 28.5 1e-07 32.1 7.2 3.3 3 0 0 3 3 3 2 LIM domain SUIM_assoc PF16619.5 OAJ28103.1 - 2.8e-09 36.9 0.0 0.00027 20.9 0.0 4.5 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 C1_1 PF00130.22 OAJ28103.1 - 9.9e-06 25.4 7.2 9.9e-06 25.4 7.2 3.5 2 1 2 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Serglycin PF04360.12 OAJ28103.1 - 0.033 14.1 0.2 0.033 14.1 0.2 5.4 4 1 1 5 5 5 0 Serglycin Suppressor_APC PF11414.8 OAJ28103.1 - 0.15 12.2 2.7 0.94 9.6 2.7 2.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein GP67 PF17634.2 OAJ28103.1 - 0.61 10.5 9.1 3.2 8.2 0.4 2.5 2 0 0 2 2 2 0 Gene product 67 KH_1 PF00013.29 OAJ28104.1 - 4.9e-32 109.6 0.9 1.1e-08 34.8 0.0 6.4 7 0 0 7 7 7 4 KH domain TENA_THI-4 PF03070.16 OAJ28105.1 - 0.00096 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family UQ_con PF00179.26 OAJ28106.1 - 1.4e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Phage_integrase PF00589.22 OAJ28107.1 - 0.0031 17.3 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family CHAP PF05257.16 OAJ28107.1 - 0.18 12.4 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 CHAP domain NST1 PF13945.6 OAJ28108.1 - 2.8e-47 161.3 0.0 2.8e-47 161.3 0.0 9.5 7 2 1 9 9 9 1 Salt tolerance down-regulator YL1 PF05764.13 OAJ28108.1 - 0.00029 21.0 19.2 0.00029 21.0 19.2 8.1 6 2 1 7 7 7 1 YL1 nuclear protein Nop14 PF04147.12 OAJ28108.1 - 0.00043 18.7 14.1 0.00043 18.7 14.1 4.9 5 1 1 6 6 6 1 Nop14-like family Nsp1_C PF05064.13 OAJ28109.1 - 2.4e-21 75.7 0.0 8.2e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Nsp1-like C-terminal region Spt20 PF12090.8 OAJ28109.1 - 3.1 7.3 14.2 5.9 6.4 14.2 1.4 1 0 0 1 1 1 0 Spt20 family PLDc_2 PF13091.6 OAJ28110.1 - 8.2e-18 64.6 0.0 2.6e-07 30.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 OAJ28110.1 - 2.2e-15 56.1 0.6 9.8e-07 28.7 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 OAJ28110.1 - 0.037 13.2 0.4 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB MULE PF10551.9 OAJ28111.1 - 6.5e-22 77.8 0.0 1.8e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ28111.1 - 7.6e-08 31.6 0.1 1.6e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 OAJ28111.1 - 3.8e-06 26.8 0.5 1e-05 25.4 0.5 1.7 1 0 0 1 1 1 1 MuDR family transposase AFT PF08731.11 OAJ28111.1 - 0.0026 18.1 0.2 0.0063 16.9 0.2 1.6 1 0 0 1 1 1 1 Transcription factor AFT zf-CCHC PF00098.23 OAJ28111.1 - 0.0042 17.1 1.5 0.0042 17.1 1.5 2.0 2 0 0 2 2 2 1 Zinc knuckle SWIM PF04434.17 OAJ28111.1 - 0.0051 16.5 5.3 0.027 14.1 1.1 2.8 2 0 0 2 2 2 1 SWIM zinc finger DUF1059 PF06348.11 OAJ28111.1 - 0.015 15.5 0.8 0.51 10.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) zf-CCHC_5 PF14787.6 OAJ28111.1 - 0.11 12.2 1.1 0.26 11.0 1.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger ResB PF05140.14 OAJ28112.1 - 0.17 10.6 1.5 0.21 10.3 1.5 1.0 1 0 0 1 1 1 0 ResB-like family TetR_C_33 PF13305.6 OAJ28112.1 - 0.19 12.5 3.9 0.27 12.0 3.8 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NEMO PF11577.8 OAJ28113.1 - 0.033 14.2 0.5 0.048 13.7 0.5 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO HicB_lk_antitox PF15919.5 OAJ28113.1 - 0.072 13.2 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Kdo_hydroxy PF11004.8 OAJ28113.1 - 0.078 12.2 0.0 0.095 12.0 0.0 1.0 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase RhlB PF12300.8 OAJ28113.1 - 0.12 12.5 5.7 0.14 12.3 5.7 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB FoP_duplication PF13865.6 OAJ28113.1 - 5.2 7.7 11.9 8.4 7.0 11.9 1.5 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pyridoxal_deC PF00282.19 OAJ28114.1 - 2.9e-94 315.9 0.0 5e-63 213.1 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 OAJ28114.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II HflK_N PF12221.8 OAJ28114.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Aminotran_5 PF00266.19 OAJ28114.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.28 OAJ28115.1 - 5.5e-212 703.9 0.0 4.5e-74 249.5 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 OAJ28115.1 - 2.4e-106 356.2 0.0 1.1e-31 110.0 0.0 4.5 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 OAJ28115.1 - 4.3e-39 132.7 2.9 5.8e-09 36.2 0.0 5.0 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ28115.1 - 2.7e-05 25.1 0.1 3 8.9 0.0 4.5 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 OAJ28115.1 - 0.0037 16.0 0.0 0.43 9.2 0.0 3.1 3 0 0 3 3 3 1 Transferase family WES_acyltransf PF03007.16 OAJ28115.1 - 0.031 14.0 0.1 5.3 6.7 0.0 3.0 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Shugoshin_N PF07558.11 OAJ28116.1 - 0.009 15.9 0.7 0.05 13.5 0.7 2.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 OAJ28116.1 - 0.045 13.6 0.5 0.045 13.6 0.5 4.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5401 PF17380.2 OAJ28116.1 - 1.1 7.3 18.1 1.9 6.5 18.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) YabA PF06156.13 OAJ28116.1 - 1.4 9.6 18.0 2.7 8.7 0.0 4.6 4 1 1 5 5 5 0 Initiation control protein YabA PEHE PF15275.6 OAJ28116.1 - 1.6 9.4 5.5 3.4 8.3 0.0 3.1 2 0 0 2 2 2 0 PEHE domain SHE3 PF17078.5 OAJ28116.1 - 3.5 7.3 17.0 7.7 6.2 11.9 2.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 OAJ28116.1 - 4.2 7.6 17.8 3.5 7.9 3.5 4.9 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II Nop14 PF04147.12 OAJ28119.1 - 0.85 7.8 4.0 1 7.5 4.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 OAJ28119.1 - 4.1 7.1 6.4 6.1 6.5 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CBFB_NFYA PF02045.15 OAJ28120.1 - 0.16 12.6 0.2 0.16 12.6 0.2 2.0 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B RVT_2 PF07727.14 OAJ28121.1 - 3e-68 230.1 0.0 4.4e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ28121.1 - 1.5e-15 57.4 0.0 2e-14 53.8 0.0 2.7 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ28121.1 - 3.1e-05 23.7 0.0 7.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3425 PF11905.8 OAJ28121.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Retrotran_gag_2 PF14223.6 OAJ28122.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ28122.1 - 0.11 12.6 2.9 0.21 11.8 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ28122.1 - 0.74 9.6 4.6 1.6 8.5 4.6 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Peroxin-13_N PF04088.13 OAJ28123.1 - 4.5e-41 140.5 0.0 6.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 OAJ28123.1 - 3e-12 46.0 0.0 5.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ28123.1 - 7.5e-12 44.8 0.0 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ28123.1 - 1.2e-09 37.8 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.22 OAJ28124.1 - 1.5e-16 59.9 0.0 3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ28124.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 OAJ28124.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Dendrin PF15498.6 OAJ28124.1 - 0.61 8.7 10.5 0.87 8.2 10.5 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin NOA36 PF06524.12 OAJ28124.1 - 1.2 8.4 7.8 2.1 7.6 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein Mito_carr PF00153.27 OAJ28125.1 - 3.9e-65 215.8 2.6 1e-21 76.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 OAJ28126.1 - 1e-45 155.2 0.0 1.3e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ28126.1 - 6.2e-16 58.7 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ28126.1 - 3.7e-07 29.8 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ28126.1 - 6.5e-05 22.9 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ28126.1 - 0.0015 18.1 0.1 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ28126.1 - 0.013 14.8 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Glutaredoxin PF00462.24 OAJ28126.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin MMR_HSR1 PF01926.23 OAJ28126.1 - 0.025 14.7 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 OAJ28126.1 - 0.034 14.2 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 OAJ28126.1 - 0.059 12.9 0.0 0.14 11.6 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 OAJ28126.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 OAJ28126.1 - 0.2 12.1 0.0 0.25 11.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DNA_pol_phi PF04931.13 OAJ28127.1 - 0.69 7.9 3.4 0.92 7.5 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi UAA PF08449.11 OAJ28128.1 - 1.4e-74 251.1 4.5 4.7e-57 193.5 0.0 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.15 OAJ28128.1 - 0.0057 15.9 0.1 0.0096 15.1 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter DBI_PRT PF02277.17 OAJ28128.1 - 0.094 11.9 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase AMPK1_CBM PF16561.5 OAJ28129.1 - 5e-11 42.7 0.8 9.1e-11 41.8 0.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glt_symporter PF03616.14 OAJ28129.1 - 4.3 5.9 5.1 7.1 5.2 0.1 3.0 3 0 0 3 3 3 0 Sodium/glutamate symporter NUDIX_2 PF13869.6 OAJ28130.1 - 3.3e-79 264.9 0.0 3.7e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase ATP-synt_C PF00137.21 OAJ28131.1 - 2.1e-27 95.3 33.0 5.3e-15 55.5 11.3 3.1 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 OAJ28131.1 - 0.024 14.2 1.1 0.024 14.2 1.1 3.0 3 1 1 4 4 4 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DNA_pol_phi PF04931.13 OAJ28133.1 - 0.038 12.1 0.2 0.049 11.7 0.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi NAD_binding_2 PF03446.15 OAJ28135.1 - 4.1e-46 157.0 0.1 4.6e-46 156.9 0.1 1.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 OAJ28135.1 - 0.00096 19.7 0.1 0.0015 19.1 0.1 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CoatB PF10389.9 OAJ28135.1 - 0.07 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage coat protein B DRTGG PF07085.12 OAJ28135.1 - 0.093 12.5 0.0 0.31 10.8 0.0 1.9 1 1 0 1 1 1 0 DRTGG domain YL1_C PF08265.11 OAJ28138.1 - 5.1e-10 38.9 2.1 1.1e-09 37.9 2.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain MOFRL PF05161.13 OAJ28138.1 - 0.18 12.0 2.9 0.31 11.3 2.9 1.4 1 0 0 1 1 1 0 MOFRL family Bac_luciferase PF00296.20 OAJ28139.1 - 0.76 9.1 7.7 0.34 10.3 3.0 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase FAD_binding_3 PF01494.19 OAJ28141.1 - 0.0058 15.9 0.0 0.0076 15.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain eIF-1a PF01176.19 OAJ28142.1 - 2.2e-21 75.4 0.0 3e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ATG_C PF09333.11 OAJ28143.1 - 1.5e-29 102.2 0.6 4.6e-29 100.6 0.2 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 OAJ28143.1 - 0.00021 21.0 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 OAJ28143.1 - 0.0054 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Fib_alpha PF08702.10 OAJ28143.1 - 0.036 14.2 0.2 0.069 13.3 0.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 OAJ28143.1 - 0.23 11.6 1.5 0.5 10.5 1.5 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Keratin_2_head PF16208.5 OAJ28143.1 - 4.9 7.3 30.2 0.14 12.3 12.6 3.2 3 0 0 3 3 3 0 Keratin type II head DPM3 PF08285.11 OAJ28144.1 - 6.4e-30 103.2 0.0 7.1e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HhH-GPD PF00730.25 OAJ28145.1 - 2.1e-09 37.8 0.0 4.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Flot PF15975.5 OAJ28145.1 - 0.045 13.9 1.6 3.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Flotillin DUF3909 PF13077.6 OAJ28145.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) Macoilin PF09726.9 OAJ28145.1 - 1.8 7.0 10.6 0.48 8.9 4.3 2.0 2 0 0 2 2 2 0 Macoilin family AA_permease PF00324.21 OAJ28146.1 - 1.4e-121 406.5 37.9 1.7e-121 406.2 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ28146.1 - 2.5e-35 122.2 42.4 3.1e-35 121.8 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 OAJ28146.1 - 0.22 12.3 9.5 3.8 8.3 0.2 3.8 3 0 0 3 3 3 0 PrgI family protein tRNA-synt_2b PF00587.25 OAJ28149.1 - 9.7e-17 61.5 0.0 9.7e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) TMF_TATA_bd PF12325.8 OAJ28149.1 - 0.044 14.0 0.2 0.076 13.2 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PTR2 PF00854.21 OAJ28150.1 - 7.3e-82 275.3 8.6 1.1e-81 274.7 8.6 1.2 1 0 0 1 1 1 1 POT family WD40 PF00400.32 OAJ28151.1 - 1.9e-12 47.5 6.1 0.05 14.5 0.0 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28151.1 - 4.3e-07 30.1 0.0 0.13 12.6 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Catalase PF00199.19 OAJ28152.1 - 2.1e-187 622.9 0.2 2.6e-187 622.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 OAJ28152.1 - 9.5e-20 70.6 0.0 2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DUF5053 PF16476.5 OAJ28152.1 - 0.089 12.5 0.3 42 3.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5053) HLH PF00010.26 OAJ28153.1 - 1.5e-07 31.3 0.3 2.6e-07 30.5 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 OAJ28153.1 - 0.00099 19.2 18.2 0.039 14.0 6.6 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 OAJ28153.1 - 0.0066 15.9 1.5 0.011 15.2 1.5 1.4 1 0 0 1 1 1 1 SDA1 RNA_pol_3_Rpc31 PF11705.8 OAJ28153.1 - 0.026 14.8 13.5 0.19 12.0 6.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ28153.1 - 0.072 11.3 5.0 0.12 10.5 5.0 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 OAJ28153.1 - 0.19 11.5 2.8 0.46 10.2 2.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein COPI_C PF06957.11 OAJ28153.1 - 0.29 9.9 1.1 0.52 9.0 1.1 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PBP1_TM PF14812.6 OAJ28153.1 - 6.5 7.2 11.9 21 5.6 11.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 OAJ28154.1 - 6.4e-41 140.4 20.8 6.4e-41 140.4 20.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ28154.1 - 6.1e-14 51.7 2.4 6.1e-14 51.7 2.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter SARAF PF06682.12 OAJ28155.1 - 1.9e-62 211.8 12.0 4.5e-62 210.6 12.0 1.6 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Imm32 PF15566.6 OAJ28156.1 - 0.32 10.8 1.6 0.84 9.5 1.6 1.6 1 0 0 1 1 1 0 Immunity protein 32 TPR_10 PF13374.6 OAJ28157.1 - 3.1e-61 201.7 92.7 0.00011 21.9 0.3 21.5 22 0 0 22 22 22 16 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28157.1 - 6.6e-46 154.5 103.2 2.6e-08 34.1 0.7 18.6 11 5 10 21 21 21 16 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ28157.1 - 1.2e-13 50.0 55.8 1.4 9.3 0.2 19.5 23 0 0 23 23 21 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28157.1 - 3.6e-08 32.9 17.9 4.7 7.2 0.1 14.1 18 0 0 18 18 18 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ28157.1 - 2.3e-07 31.0 40.4 0.096 12.8 0.1 8.7 3 2 5 10 10 10 5 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 OAJ28157.1 - 0.00019 21.4 37.0 22 5.6 0.0 14.9 19 0 0 19 19 17 0 Tetratricopeptide repeat SRC-1 PF08832.10 OAJ28157.1 - 0.016 16.3 0.3 0.048 14.7 0.2 1.9 1 1 0 1 1 1 0 Steroid receptor coactivator Na_Ca_ex_C PF16494.5 OAJ28157.1 - 0.078 13.4 1.8 6.1 7.3 0.1 4.4 3 1 1 4 4 4 0 C-terminal extension of sodium/calcium exchanger domain DUF4007 PF13182.6 OAJ28157.1 - 0.29 10.2 1.8 4.1 6.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4007) MIT PF04212.18 OAJ28157.1 - 0.93 9.6 0.0 0.93 9.6 0.0 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 OAJ28157.1 - 1.5 9.1 12.6 7 7.0 1.6 6.0 4 2 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 OAJ28157.1 - 3.1 7.3 27.9 0.54 9.7 0.1 9.7 13 0 0 13 13 13 0 SHNi-TPR Wzy_C_2 PF11846.8 OAJ28157.1 - 4.8 7.1 15.0 0.72 9.8 0.5 5.4 5 2 2 7 7 7 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 OAJ28158.1 - 0.0065 16.7 0.0 0.034 14.4 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Tim54 PF11711.8 OAJ28158.1 - 0.26 10.0 1.5 0.37 9.5 0.0 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 OAJ28158.1 - 3.8 7.6 6.6 0.22 11.6 0.2 2.1 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Aminotran_3 PF00202.21 OAJ28159.1 - 9e-89 297.9 0.0 1.2e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Virul_Fac PF10139.9 OAJ28160.1 - 0.057 11.6 0.2 0.086 11.0 0.2 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF4611 PF15387.6 OAJ28160.1 - 3 8.1 8.7 0.1 12.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MS_channel PF00924.18 OAJ28161.1 - 3.1e-24 85.7 0.6 5.7e-24 84.8 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Flu_PB2 PF00604.17 OAJ28161.1 - 0.16 9.9 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 RVT_2 PF07727.14 OAJ28162.1 - 1.7e-61 207.9 0.0 2.4e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ28162.1 - 5.1e-14 52.5 0.0 2.9e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ28162.1 - 9.7e-14 51.2 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ28162.1 - 7.8e-06 25.7 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 OAJ28162.1 - 9e-06 25.2 0.1 1.7e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) RVT_3 PF13456.6 OAJ28162.1 - 0.0083 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like rve_3 PF13683.6 OAJ28162.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Retrotran_gag_3 PF14244.6 OAJ28162.1 - 0.093 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 OAJ28162.1 - 0.2 11.8 5.1 0.47 10.6 5.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ28162.1 - 7.7 6.5 10.4 0.36 10.7 3.7 2.2 2 0 0 2 2 2 0 Zinc knuckle HRG PF16954.5 OAJ28163.1 - 0.0032 17.8 3.2 0.028 14.8 0.1 2.9 2 0 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene Wzy_C PF04932.15 OAJ28163.1 - 0.0063 16.2 1.1 0.12 12.0 0.1 2.4 2 0 0 2 2 2 1 O-Antigen ligase ATG27 PF09451.10 OAJ28163.1 - 0.18 11.6 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Pkinase_Tyr PF07714.17 OAJ28165.1 - 7.8e-09 35.2 0.0 8.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 OAJ28165.1 - 8e-09 35.2 0.0 7.6e-06 25.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 OAJ28165.1 - 0.0012 18.8 0.2 0.002 18.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ28165.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 OAJ28165.1 - 0.11 11.9 0.0 0.36 10.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family H_lectin PF09458.10 OAJ28166.1 - 2.7e-11 43.5 0.1 5.9e-08 32.8 0.1 2.7 2 0 0 2 2 2 2 H-type lectin domain SecA_SW PF07516.13 OAJ28166.1 - 0.021 14.9 4.6 0.066 13.3 1.9 2.4 2 1 0 2 2 2 0 SecA Wing and Scaffold domain CR6_interact PF10147.9 OAJ28166.1 - 0.072 12.8 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Pneumo_M2 PF07380.11 OAJ28168.1 - 0.18 12.1 0.9 0.27 11.5 0.9 1.3 1 0 0 1 1 1 0 Pneumovirus M2 protein Complex1_LYR PF05347.15 OAJ28169.1 - 2.1e-07 30.9 5.9 3.9e-07 30.0 5.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ORC6 PF05460.13 OAJ28169.1 - 0.07 12.4 0.2 0.097 11.9 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NDC10_II PF16787.5 OAJ28170.1 - 1.7e-41 142.3 0.0 2.2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ28170.1 - 5.4e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes HTH_Tnp_1 PF01527.20 OAJ28170.1 - 0.052 13.9 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 Transposase HTH_Tnp_1_2 PF13022.6 OAJ28170.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase MWFE PF15879.5 OAJ28171.1 - 8.7e-25 86.7 0.6 1.1e-24 86.3 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF4405 PF14358.6 OAJ28171.1 - 0.13 12.9 0.0 0.15 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) RRM_1 PF00076.22 OAJ28173.1 - 0.001 18.9 0.0 0.2 11.5 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.12 OAJ28173.1 - 0.038 12.2 31.9 0.066 11.4 9.0 2.0 2 0 0 2 2 2 0 Nop14-like family UPF0052 PF01933.18 OAJ28174.1 - 2.3e-39 135.4 0.0 2.5e-38 132.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 RNB PF00773.19 OAJ28175.1 - 1.1e-92 310.8 0.0 1.5e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 OAJ28175.1 - 4.4e-24 84.9 0.0 9e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 OAJ28175.1 - 1.6e-20 72.9 0.1 3e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 OAJ28175.1 - 9.2e-19 67.3 0.0 2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 OAJ28175.1 - 5.9e-08 32.8 0.0 2.6e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 OAJ28175.1 - 1e-07 32.3 0.0 4.1e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 PIN domain VPS13_mid_rpt PF16910.5 OAJ28176.1 - 6.1e-94 313.8 9.7 8.4e-92 306.8 2.8 4.8 4 0 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 OAJ28176.1 - 9.6e-83 277.7 0.0 6.1e-79 265.2 0.0 4.1 4 0 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 OAJ28176.1 - 2.2e-82 276.4 2.9 3.4e-79 266.0 0.1 3.6 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 OAJ28176.1 - 1.1e-75 253.3 3.5 6.2e-70 234.6 0.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 OAJ28176.1 - 7e-40 135.8 0.1 5.7e-39 132.8 0.0 2.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 OAJ28176.1 - 1.5e-09 38.0 0.2 3.1e-08 33.8 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain RRM_1 PF00076.22 OAJ28177.1 - 6.8e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N2227 PF07942.12 OAJ28177.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein Pkinase PF00069.25 OAJ28178.1 - 7.8e-77 258.2 0.1 1.1e-76 257.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28178.1 - 2.3e-41 141.8 0.0 3.8e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 OAJ28178.1 - 2.8e-21 75.5 0.0 4.6e-09 36.3 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 OAJ28178.1 - 1.6e-08 34.2 0.0 3.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ28178.1 - 0.0023 16.8 0.0 0.0043 15.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ28178.1 - 0.004 16.2 0.0 0.0067 15.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ28178.1 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ28178.1 - 0.85 9.5 3.6 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tfb5 PF06331.12 OAJ28179.1 - 8.3e-27 93.0 0.2 9e-27 92.9 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 BTB PF00651.31 OAJ28180.1 - 2.3e-14 53.6 0.5 1.4e-09 38.2 0.0 3.6 3 0 0 3 3 3 3 BTB/POZ domain CAP_GLY PF01302.25 OAJ28180.1 - 3.3e-07 30.2 0.7 1.7e-06 27.9 0.1 2.5 3 0 0 3 3 3 1 CAP-Gly domain Pyr_redox_2 PF07992.14 OAJ28181.1 - 0.00013 21.3 0.0 0.00077 18.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.11 OAJ28182.1 - 0.00093 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 LisH COG2 PF06148.11 OAJ28183.1 - 0.021 14.9 0.5 0.021 14.9 0.5 5.2 2 1 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 PAM2 PF07145.15 OAJ28183.1 - 0.35 10.7 2.0 8.7 6.3 0.2 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region AMP-binding PF00501.28 OAJ28184.1 - 1.5e-32 112.7 0.1 3.9e-32 111.4 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ28184.1 - 5.8e-25 87.9 0.0 9.6e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 OAJ28184.1 - 1.8e-08 34.2 0.0 4.9e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 OAJ28184.1 - 5.4e-06 26.7 0.0 1.3e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 OAJ28184.1 - 0.059 14.3 0.3 2.5 9.1 0.1 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 OAJ28184.1 - 0.19 10.8 0.0 6.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein p450 PF00067.22 OAJ28185.1 - 1.4e-78 264.7 0.0 1.7e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PspB PF06667.12 OAJ28185.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B Co_AT_N PF12557.8 OAJ28185.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal ketoacyl-synt PF00109.26 OAJ28186.1 - 2.6e-74 250.0 0.0 5.1e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 OAJ28186.1 - 1.5e-43 149.5 0.0 1.3e-41 143.1 0.0 3.4 3 1 1 4 4 4 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 OAJ28186.1 - 1.8e-33 115.0 0.8 4.4e-33 113.8 0.8 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 OAJ28186.1 - 1.8e-27 96.4 0.0 3.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 OAJ28186.1 - 1.1e-23 84.3 4.8 1.1e-21 77.7 2.3 3.3 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thioesterase PF00975.20 OAJ28186.1 - 2.2e-23 83.6 0.1 4.6e-22 79.3 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 OAJ28186.1 - 5.4e-15 55.5 3.3 2.2e-06 27.9 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 OAJ28186.1 - 8.7e-10 39.6 3.1 2.2e-08 35.0 0.1 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 OAJ28186.1 - 4.3e-07 30.4 0.0 1e-06 29.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 OAJ28186.1 - 0.00036 20.0 0.1 0.00089 18.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 OAJ28186.1 - 0.00084 19.1 0.1 0.091 12.5 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ28186.1 - 0.014 15.0 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 OAJ28186.1 - 0.078 12.8 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold ACP_syn_III PF08545.10 OAJ28186.1 - 0.1 12.5 1.3 0.54 10.1 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 OAJ28187.1 - 2.2e-05 23.4 0.0 2.2e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sporozoite_P67 PF05642.11 OAJ28188.1 - 0.24 9.5 21.3 0.28 9.2 21.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen D123 PF07065.14 OAJ28188.1 - 0.92 8.6 13.4 1 8.4 13.4 1.2 1 0 0 1 1 1 0 D123 POX PF07526.11 OAJ28188.1 - 5.8 7.5 9.8 6.8 7.3 9.8 1.2 1 0 0 1 1 1 0 Associated with HOX CobT PF06213.12 OAJ28188.1 - 8.9 5.6 33.6 9.1 5.6 33.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Fasciclin PF02469.22 OAJ28189.1 - 3.4e-11 43.5 0.0 5.1e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 Fasciclin domain Xpo1 PF08389.12 OAJ28190.1 - 0.0025 17.9 0.0 0.0095 16.0 0.0 1.9 2 0 0 2 2 2 1 Exportin 1-like protein FAT PF02259.23 OAJ28191.1 - 5.4e-65 219.9 2.0 5.4e-65 219.9 2.0 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 OAJ28191.1 - 4.3e-28 98.8 0.0 2.6e-27 96.2 0.0 2.4 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 OAJ28191.1 - 0.032 14.1 0.2 0.078 12.8 0.2 1.7 1 0 0 1 1 1 0 FATC domain AAA_5 PF07728.14 OAJ28193.1 - 1.5e-35 122.2 0.0 4.8e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) SPT2 PF08243.11 OAJ28195.1 - 0.07 13.7 2.4 0.098 13.2 2.4 1.5 1 1 0 1 1 1 0 SPT2 chromatin protein MHB PF16525.5 OAJ28195.1 - 0.078 13.2 0.2 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Haemophore, haem-binding Pkinase PF00069.25 OAJ28196.1 - 9.1e-43 146.5 0.0 1.6e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28196.1 - 9.7e-18 64.4 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAJ28196.1 - 0.0037 16.9 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ28196.1 - 0.0077 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF294_C PF10335.9 OAJ28196.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain Kinase-like PF14531.6 OAJ28196.1 - 0.051 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Transket_pyr PF02779.24 OAJ28197.1 - 1.1e-60 204.4 0.0 1.8e-60 203.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 OAJ28197.1 - 2.1e-45 155.0 0.0 7.2e-45 153.2 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 OAJ28197.1 - 1.5e-36 125.3 0.0 2.3e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal PQ-loop PF04193.14 OAJ28198.1 - 4.2e-14 52.1 0.2 2.4e-12 46.4 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Amidinotransf PF02274.17 OAJ28199.1 - 8e-13 48.2 0.0 7.8e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 Amidinotransferase MMtag PF10159.9 OAJ28200.1 - 1.7e-30 105.2 2.2 1.7e-30 105.2 2.2 2.9 2 1 0 2 2 2 1 Multiple myeloma tumor-associated DUF4042 PF13251.6 OAJ28201.1 - 3.1e-09 36.8 4.2 1.3e-08 34.8 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 OAJ28201.1 - 0.0013 19.1 33.3 0.018 15.4 3.8 6.7 4 2 3 7 7 7 5 HEAT repeats SAM_DrpA PF18255.1 OAJ28201.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain HEAT PF02985.22 OAJ28201.1 - 0.1 12.9 36.2 2.9 8.4 0.5 9.6 10 0 0 10 10 10 0 HEAT repeat HEAT_EZ PF13513.6 OAJ28201.1 - 1.1 9.9 31.7 0.49 10.9 0.4 7.5 7 1 2 9 9 9 0 HEAT-like repeat Cyto_heme_lyase PF01265.17 OAJ28202.1 - 2.3e-69 234.2 18.0 1.1e-54 186.0 11.0 3.1 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase Clat_adaptor_s PF01217.20 OAJ28203.1 - 1.4e-43 148.2 0.3 5e-34 117.3 0.3 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 OAJ28204.1 - 0.096 11.5 1.1 0.19 10.5 1.1 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_S7e PF01251.18 OAJ28205.1 - 6.1e-81 270.6 0.1 9.7e-81 269.9 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S7e Thr_synth_N PF14821.6 OAJ28206.1 - 2e-25 88.8 0.0 7.3e-25 87.0 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 OAJ28206.1 - 2.2e-19 70.0 0.0 1.3e-18 67.4 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CC2-LZ PF16516.5 OAJ28206.1 - 0.055 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CAF1C_H4-bd PF12265.8 OAJ28208.1 - 2.5e-28 98.1 0.1 5.9e-28 96.9 0.1 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 OAJ28208.1 - 4.2e-25 87.5 10.3 0.00014 22.6 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28208.1 - 2.2e-06 27.9 1.1 0.019 15.3 0.1 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Rad51 PF08423.11 OAJ28209.1 - 3.5e-128 426.2 0.1 4.2e-128 426.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 OAJ28209.1 - 7.6e-12 45.2 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 OAJ28209.1 - 5.8e-10 39.1 0.1 7.9e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 OAJ28209.1 - 3.3e-07 29.9 0.1 6.4e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.6 OAJ28209.1 - 6.7e-06 26.6 0.2 1.7e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DnaB_C PF03796.15 OAJ28209.1 - 0.0032 16.8 0.1 0.03 13.6 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 OAJ28209.1 - 0.0042 16.3 1.0 0.034 13.3 0.6 2.0 1 1 1 2 2 2 1 PAXNEB protein HHH PF00633.23 OAJ28209.1 - 0.036 13.9 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans PF04082.18 OAJ28210.1 - 0.0003 19.9 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ28210.1 - 0.0057 16.8 14.8 0.0091 16.1 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.22 OAJ28211.1 - 7.7e-39 132.8 0.0 4.4e-08 33.4 0.0 6.5 5 2 0 5 5 5 5 Fasciclin domain Rep_fac_C PF08542.11 OAJ28211.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain DUF4381 PF14316.6 OAJ28211.1 - 0.23 11.7 1.5 0.55 10.5 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Aminotran_1_2 PF00155.21 OAJ28212.1 - 2.4e-40 138.9 0.0 4.3e-40 138.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 OAJ28212.1 - 0.00014 20.5 0.0 0.00034 19.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PfkB PF00294.24 OAJ28213.1 - 0.001 18.4 1.2 0.019 14.3 0.6 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase UBX PF00789.20 OAJ28214.1 - 1.2e-06 28.6 0.0 4.5e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 OAJ28214.1 - 7.4e-05 22.6 0.0 0.00023 21.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF572 PF04502.13 OAJ28214.1 - 0.015 14.9 17.1 0.021 14.5 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2 PF00096.26 OAJ28214.1 - 0.044 14.3 0.1 0.072 13.6 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zinc_ribbon_4 PF13717.6 OAJ28214.1 - 0.096 12.6 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Rtf2 PF04641.12 OAJ28214.1 - 0.13 11.6 21.0 0.21 10.9 21.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger GREB1 PF15782.5 OAJ28214.1 - 0.59 7.2 3.3 0.63 7.1 3.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 OAJ28214.1 - 1.7 8.6 23.0 2.6 8.1 23.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C2H2_2 PF12756.7 OAJ28214.1 - 2.6 8.4 7.2 0.33 11.3 0.3 2.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SKN1 PF03935.15 OAJ28215.1 - 2.8e-175 583.5 2.8 3.2e-175 583.3 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) BAR_2 PF10455.9 OAJ28216.1 - 1.4e-41 142.5 0.0 4.3e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 OAJ28216.1 - 6.5e-12 45.6 1.1 3.2e-09 36.8 0.2 2.1 2 0 0 2 2 2 2 BAR domain HAUS2 PF15003.6 OAJ28216.1 - 0.066 12.9 0.8 0.17 11.6 0.8 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Seryl_tRNA_N PF02403.22 OAJ28216.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.0 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1090 PF06476.12 OAJ28216.1 - 1.7 8.8 9.0 0.1 12.7 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Met_10 PF02475.16 OAJ28217.1 - 8e-51 172.6 0.0 3.1e-40 138.1 0.0 2.3 2 0 0 2 2 2 2 Met-10+ like-protein PhoD PF09423.10 OAJ28218.1 - 0.00042 19.4 0.0 0.035 13.1 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Dehydrin PF00257.19 OAJ28218.1 - 0.0044 17.6 0.1 0.0096 16.5 0.1 1.5 1 0 0 1 1 1 1 Dehydrin EOS1 PF12326.8 OAJ28219.1 - 0.016 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF1418 PF07214.12 OAJ28219.1 - 0.27 11.1 1.7 0.84 9.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) F-box PF00646.33 OAJ28220.1 - 3.7e-07 29.8 0.1 6.5e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ28220.1 - 0.00012 21.9 0.1 0.00028 20.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ28220.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 F-box PBD PF00786.28 OAJ28221.1 - 0.0013 19.1 0.0 0.0013 19.1 0.0 2.1 3 0 0 3 3 3 1 P21-Rho-binding domain CDC45 PF02724.14 OAJ28222.1 - 0.19 10.0 7.2 0.2 9.9 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.12 OAJ28222.1 - 0.24 9.7 3.1 0.31 9.3 3.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RVT_1 PF00078.27 OAJ28225.1 - 4.7e-23 81.9 0.0 7.7e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ28225.1 - 10 5.6 10.3 1.3 8.4 2.9 3.0 2 1 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family AA_permease PF00324.21 OAJ28226.1 - 9.1e-136 453.2 47.6 1.1e-135 453.0 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ28226.1 - 2.5e-38 132.0 50.4 3.1e-38 131.7 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3093 PF11292.8 OAJ28226.1 - 0.06 13.6 0.2 0.06 13.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3093) YpmT PF17431.2 OAJ28226.1 - 0.27 11.3 3.0 0.3 11.1 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized YmpT-like DnaJ_C PF01556.18 OAJ28227.1 - 2.7e-41 141.1 1.2 3.7e-41 140.7 1.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ28227.1 - 3.8e-21 75.0 0.2 6.6e-21 74.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ28227.1 - 6.1e-16 58.5 19.7 9.8e-16 57.9 19.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 OAJ28227.1 - 0.0045 16.9 9.5 0.019 14.9 1.1 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 OAJ28227.1 - 6 6.9 12.2 7.4 6.6 3.7 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PS_Dcarbxylase PF02666.15 OAJ28228.1 - 3.9e-73 245.3 0.0 1.5e-55 187.9 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 OAJ28228.1 - 0.00091 18.9 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 MNLL subunit NTP_transf_9 PF04248.12 OAJ28230.1 - 5.2e-31 106.4 1.0 5.8e-30 103.0 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF427) DUF1691 PF07950.11 OAJ28231.1 - 1.9e-05 25.3 7.1 3.6e-05 24.4 0.5 3.4 3 2 0 3 3 3 1 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 OAJ28231.1 - 0.00018 21.6 1.1 0.0019 18.2 0.1 2.6 2 1 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4405 PF14358.6 OAJ28231.1 - 0.011 16.3 0.5 0.46 11.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) zf-C3Hc3H PF13891.6 OAJ28232.1 - 0.4 11.1 6.9 0.11 12.9 2.5 2.0 1 1 1 2 2 2 0 Potential DNA-binding domain Yip1 PF04893.17 OAJ28233.1 - 5.5e-09 36.0 11.5 5.5e-09 36.0 11.5 1.5 2 0 0 2 2 2 1 Yip1 domain DUF2070 PF09843.9 OAJ28233.1 - 2.5 6.3 8.2 3.3 5.9 8.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LCM PF04072.14 OAJ28234.1 - 4.2e-14 52.9 0.0 5.5e-08 33.0 0.0 2.6 3 0 0 3 3 3 2 Leucine carboxyl methyltransferase NT-C2 PF10358.9 OAJ28235.1 - 1.5e-11 44.2 0.0 0.0017 18.1 0.0 3.7 3 1 0 3 3 3 3 N-terminal C2 in EEIG1 and EHBP1 proteins NOA36 PF06524.12 OAJ28235.1 - 1.5 8.1 10.8 3.4 6.9 10.8 1.5 1 0 0 1 1 1 0 NOA36 protein CCD PF07860.11 OAJ28235.1 - 5.5 7.0 10.3 4.4 7.4 7.6 2.2 2 0 0 2 2 2 0 WisP family C-Terminal Region HOIP-UBA PF16678.5 OAJ28236.1 - 0.0015 18.5 0.0 0.0042 17.1 0.0 1.7 1 0 0 1 1 1 1 HOIP UBA domain pair UBA PF00627.31 OAJ28236.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain DUF936 PF06075.12 OAJ28238.1 - 0.035 13.0 12.9 0.042 12.8 12.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SOG2 PF10428.9 OAJ28238.1 - 0.95 8.6 20.0 1.2 8.2 20.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1387 PF07139.11 OAJ28238.1 - 1.2 8.8 11.0 1.5 8.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Chitin_synth_2 PF03142.15 OAJ28239.1 - 9.2e-246 816.5 0.0 1.2e-245 816.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 OAJ28239.1 - 1.5e-89 301.0 0.0 8.7e-89 298.5 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 OAJ28239.1 - 2.2e-15 56.5 0.1 1.5e-11 44.3 0.0 2.8 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAJ28239.1 - 8.7e-15 55.2 0.0 6.2e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 OAJ28239.1 - 7.4e-14 52.1 3.1 7.4e-14 52.1 3.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.11 OAJ28239.1 - 4.8e-13 48.8 0.0 1e-11 44.6 0.0 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.26 OAJ28239.1 - 4.3e-09 36.4 0.0 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 OAJ28239.1 - 1.5e-05 24.6 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Hydrophobin PF01185.18 OAJ28240.1 - 3.1 8.5 11.2 4.2 8.1 0.1 3.3 2 1 1 3 3 3 0 Fungal hydrophobin Pkinase PF00069.25 OAJ28241.1 - 5.7e-21 75.1 0.0 7.5e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28241.1 - 7.3e-17 61.5 0.0 9.1e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Transposase_21 PF02992.14 OAJ28242.1 - 2.3e-17 62.9 0.0 4.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ28242.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Nup88 PF10168.9 OAJ28244.1 - 0.2 9.5 20.0 0.26 9.0 20.0 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF4574 PF15141.6 OAJ28244.1 - 0.3 11.0 5.5 0.91 9.5 5.0 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 ADIP PF11559.8 OAJ28244.1 - 1.9 8.6 28.5 4.1 7.5 12.7 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TRF PF08558.10 OAJ28244.1 - 2.5 7.6 14.3 0.41 10.2 7.4 2.1 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) Histone PF00125.24 OAJ28246.1 - 9.1e-43 145.8 4.1 4.1e-42 143.6 4.1 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ28246.1 - 2.1e-05 24.6 0.1 3.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 OAJ28246.1 - 3.8e-05 24.0 0.0 6.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 OAJ28246.1 - 0.0028 17.9 0.2 0.0044 17.3 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4840 PF16128.5 OAJ28246.1 - 0.17 11.9 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) Sirohm_synth_M PF14824.6 OAJ28246.1 - 0.21 11.0 1.1 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central PAF PF15715.5 OAJ28246.1 - 0.26 11.9 1.7 0.36 11.4 1.7 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain BUD22 PF09073.10 OAJ28247.1 - 0.11 11.8 3.3 0.14 11.5 3.3 1.1 1 0 0 1 1 1 0 BUD22 Transglut_core3 PF13471.6 OAJ28250.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily Methyltransf_11 PF08241.12 OAJ28251.1 - 1.1e-19 70.8 0.1 8.2e-19 68.1 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ28251.1 - 2.9e-19 69.6 0.0 1e-18 67.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ28251.1 - 7.5e-16 58.3 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ28251.1 - 5.9e-11 43.0 0.0 1.2e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ28251.1 - 1.4e-10 40.9 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 OAJ28251.1 - 6.6e-09 35.8 0.0 9.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OAJ28251.1 - 0.00024 20.8 0.0 0.0011 18.7 0.0 1.9 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OAJ28251.1 - 0.00033 20.2 0.0 0.0014 18.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 OAJ28251.1 - 0.0005 18.7 0.0 0.00065 18.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 OAJ28251.1 - 0.00054 19.5 0.0 0.0016 17.9 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 OAJ28251.1 - 0.0057 16.7 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ28251.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.10 OAJ28251.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase RrnaAD PF00398.20 OAJ28251.1 - 0.059 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 OAJ28251.1 - 0.12 13.4 0.0 0.32 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 OAJ28251.1 - 0.15 11.9 0.0 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PrmA PF06325.13 OAJ28251.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Lung_7-TM_R PF06814.13 OAJ28253.1 - 1.3e-50 172.4 19.1 2.1e-50 171.7 19.1 1.3 1 1 0 1 1 1 1 Lung seven transmembrane receptor Tub_N PF16322.5 OAJ28253.1 - 0.11 13.0 0.1 0.11 13.0 0.1 1.5 2 0 0 2 2 2 0 Tubby N-terminal DUF3671 PF12420.8 OAJ28253.1 - 0.17 11.9 2.9 0.61 10.2 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function YlaC PF10777.9 OAJ28253.1 - 0.54 10.1 8.3 0.59 10.0 3.1 2.4 2 0 0 2 2 2 0 Inner membrane protein YlaC PepSY_TM PF03929.16 OAJ28253.1 - 0.74 9.4 15.2 0.54 9.9 10.5 2.8 2 1 1 3 3 3 0 PepSY-associated TM region S1 PF00575.23 OAJ28254.1 - 5.4e-31 106.8 9.7 4.8e-07 30.0 0.8 8.2 8 0 0 8 8 8 5 S1 RNA binding domain Suf PF05843.14 OAJ28254.1 - 2e-09 37.9 1.3 5.8e-07 29.8 0.0 3.6 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 OAJ28254.1 - 2.9e-06 27.7 0.0 2.6 8.6 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat NRDE-2 PF08424.10 OAJ28254.1 - 7.1e-06 25.4 4.6 0.00021 20.5 1.7 2.9 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 OAJ28254.1 - 0.00039 21.0 1.9 9.6 7.3 0.0 5.8 3 2 1 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ28254.1 - 0.0017 17.6 2.6 0.0035 16.6 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF2110 PF09883.9 OAJ28254.1 - 0.0044 16.7 0.3 3.4 7.2 0.0 3.9 3 1 1 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2110) TPR_16 PF13432.6 OAJ28254.1 - 0.007 17.0 0.0 0.007 17.0 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat Radial_spoke PF04712.12 OAJ28254.1 - 0.017 14.1 0.2 0.017 14.1 0.2 3.4 3 0 0 3 3 1 0 Radial spokehead-like protein Sigma70_ner PF04546.13 OAJ28254.1 - 0.03 14.2 0.2 0.03 14.2 0.2 5.4 5 1 1 6 6 4 0 Sigma-70, non-essential region TPR_6 PF13174.6 OAJ28254.1 - 0.043 14.5 0.8 2.4 9.0 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TFIIA PF03153.13 OAJ28254.1 - 2 8.3 45.8 0.79 9.7 20.4 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit NUDIX PF00293.28 OAJ28255.1 - 1.4e-10 41.3 0.0 3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Collagen PF01391.18 OAJ28257.1 - 3.8e-13 49.0 81.1 0.00018 21.2 19.0 3.8 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) GCD14 PF08704.10 OAJ28258.1 - 1.3e-72 244.5 2.9 1.1e-29 103.9 0.1 4.2 4 0 0 4 4 4 4 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 OAJ28258.1 - 0.0019 18.0 0.0 0.0046 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ldh_1_N PF00056.23 OAJ28259.1 - 1.7e-46 157.9 0.5 2.4e-46 157.3 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 OAJ28259.1 - 4.9e-46 156.7 0.0 7.9e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 OAJ28259.1 - 3.7e-06 26.2 0.0 6.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 OAJ28259.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 OAJ28259.1 - 0.003 16.9 0.3 0.048 13.0 0.3 2.3 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 OAJ28259.1 - 0.02 14.5 0.2 0.97 9.0 0.0 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Mito_carr PF00153.27 OAJ28260.1 - 2.4e-43 145.9 6.0 6.3e-17 61.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S24e PF01282.19 OAJ28261.1 - 4.5e-32 109.8 0.1 7.9e-32 109.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Sec39 PF08314.11 OAJ28262.1 - 0.24 9.8 0.3 0.39 9.1 0.3 1.3 1 0 0 1 1 1 0 Secretory pathway protein Sec39 ELP6 PF09807.9 OAJ28263.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Elongation complex protein 6 AAA_25 PF13481.6 OAJ28263.1 - 8.8e-06 25.4 0.1 1.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ28263.1 - 0.0088 16.0 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 NACHT domain DUF4990 PF16380.5 OAJ28263.1 - 0.074 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Aminotran_5 PF00266.19 OAJ28264.1 - 3.5e-29 101.9 0.0 5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 OAJ28264.1 - 4.1e-27 95.0 49.1 1.3e-26 93.4 48.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4028 PF13220.6 OAJ28265.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4028) ABC2_membrane PF01061.24 OAJ28266.1 - 1.8e-13 50.4 13.4 2.7e-09 36.8 0.4 2.4 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ28266.1 - 6e-12 46.2 0.0 1e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF4407 PF14362.6 OAJ28266.1 - 0.016 14.6 0.2 0.039 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_21 PF13304.6 OAJ28266.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Pkinase PF00069.25 OAJ28267.1 - 3.1e-72 243.1 0.0 3.9e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28267.1 - 3.7e-31 108.3 0.0 4.9e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ28267.1 - 2.7e-14 53.6 1.1 8e-14 52.1 1.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 OAJ28267.1 - 1.4e-06 27.5 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 OAJ28267.1 - 0.0002 20.8 0.0 0.00072 19.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 OAJ28267.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ28267.1 - 0.0096 15.6 0.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAJ28267.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ceramidase_alk PF04734.13 OAJ28268.1 - 8.3e-174 578.9 0.0 9.7e-173 575.4 0.0 2.2 1 1 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 OAJ28268.1 - 3.7e-36 124.5 0.1 7.5e-36 123.5 0.1 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal HAP1_N PF04849.13 OAJ28269.1 - 0.011 14.9 18.4 0.05 12.8 14.4 3.0 2 1 0 2 2 2 0 HAP1 N-terminal conserved region zf-C4H2 PF10146.9 OAJ28269.1 - 0.23 11.8 2.6 0.84 9.9 2.6 2.1 1 0 0 1 1 1 0 Zinc finger-containing protein ABC_tran_CTD PF16326.5 OAJ28269.1 - 0.77 10.0 16.4 0.16 12.3 10.2 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain PRODH PF18327.1 OAJ28269.1 - 0.79 10.0 6.9 4.6 7.5 0.3 2.9 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain Abhydrolase_2 PF02230.16 OAJ28270.1 - 0.025 14.4 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2062 PF09835.9 OAJ28272.1 - 0.082 12.8 5.8 0.4 10.5 2.7 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) ATG22 PF11700.8 OAJ28273.1 - 8.5e-122 407.2 20.1 1e-121 406.9 20.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MOSC PF03473.17 OAJ28274.1 - 1.5e-18 67.1 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 OAJ28274.1 - 5.5e-08 32.7 0.0 0.00027 20.8 0.0 2.7 2 0 0 2 2 2 2 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 OAJ28274.1 - 7.4e-08 31.7 0.0 3.8e-06 26.1 0.0 3.1 2 1 0 2 2 2 1 Aminotransferase class-V SKN1 PF03935.15 OAJ28275.1 - 1.9e-176 587.4 2.0 2.2e-176 587.1 2.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GST_N PF02798.20 OAJ28276.1 - 2.5e-13 50.1 0.2 7.1e-13 48.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ28276.1 - 5.3e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ28276.1 - 8.3e-10 38.9 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ28276.1 - 5.9e-09 36.1 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ28276.1 - 5.6e-07 29.5 0.1 1.5e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ28276.1 - 2.2e-05 24.6 0.0 5.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 OAJ28276.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bac_rhodopsin PF01036.18 OAJ28277.1 - 6.1e-50 169.9 20.3 8e-50 169.5 20.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein AgrB PF04647.15 OAJ28277.1 - 0.0099 15.2 1.3 0.0099 15.2 1.3 1.8 2 0 0 2 2 2 1 Accessory gene regulator B Heliorhodopsin PF18761.1 OAJ28277.1 - 0.038 13.3 10.5 0.011 15.1 7.2 1.7 1 1 0 1 1 1 0 Heliorhodopsin Arteri_Gl PF00951.18 OAJ28277.1 - 0.97 9.2 5.6 0.16 11.7 1.3 1.9 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein DUF4131 PF13567.6 OAJ28277.1 - 1.2 8.7 7.8 1.5 8.5 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF2754 PF10953.8 OAJ28277.1 - 9.5 6.5 7.9 10 6.4 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) Acyltransferase PF01553.21 OAJ28278.1 - 1e-14 54.3 0.0 1.1e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Acyltransferase BPL_LplA_LipB PF03099.19 OAJ28279.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 OAJ28279.1 - 0.15 12.1 0.0 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Pkinase PF00069.25 OAJ28280.1 - 0.0005 19.5 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28280.1 - 0.0006 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ28280.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ28280.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GHMP_kinases_N PF00288.26 OAJ28282.1 - 8e-14 51.6 4.9 1.9e-13 50.4 3.4 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ28282.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4813 PF16072.5 OAJ28282.1 - 0.59 9.7 7.2 0.041 13.6 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) CorA PF01544.18 OAJ28283.1 - 7.5e-45 153.5 0.1 1.1e-44 153.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Kdo PF06293.14 OAJ28284.1 - 4e-06 26.3 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAJ28284.1 - 6.6e-05 22.4 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAJ28284.1 - 0.00027 19.9 0.0 0.00036 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 OAJ28284.1 - 0.0023 17.9 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 OAJ28284.1 - 0.0037 16.6 0.0 0.0072 15.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 OAJ28285.1 - 2.6e-05 23.7 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 OAJ28285.1 - 0.00017 21.0 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 OAJ28285.1 - 0.00067 18.5 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 OAJ28285.1 - 0.014 14.7 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 OAJ28285.1 - 0.035 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mon1 PF03164.14 OAJ28287.1 - 2.4e-79 267.3 0.0 1.4e-51 175.9 0.0 2.6 2 1 0 2 2 2 2 Trafficking protein Mon1 Solute_trans_a PF03619.16 OAJ28288.1 - 1.2e-74 251.2 12.7 1.4e-74 251.0 12.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PepSY_TM PF03929.16 OAJ28288.1 - 0.0038 16.9 0.0 0.0092 15.7 0.0 1.6 1 0 0 1 1 1 1 PepSY-associated TM region Nramp PF01566.18 OAJ28288.1 - 0.0056 15.7 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Dopey_N PF04118.14 OAJ28289.1 - 7.2e-105 350.5 0.0 2.8e-104 348.6 0.0 2.1 2 0 0 2 2 2 1 Dopey, N-terminal UCR_hinge PF02320.16 OAJ28290.1 - 4.2e-11 42.9 3.2 7.4e-11 42.1 3.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein ORC_WH_C PF18137.1 OAJ28290.1 - 0.011 15.8 2.4 0.015 15.4 2.4 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal CEND1 PF15677.5 OAJ28290.1 - 0.086 13.4 6.3 0.06 13.9 3.6 1.8 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 RR_TM4-6 PF06459.12 OAJ28290.1 - 4.1 7.2 8.0 5.3 6.8 8.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pribosyltran PF00156.27 OAJ28291.1 - 5.1e-17 61.8 0.4 7.3e-17 61.3 0.4 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 OAJ28291.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase NABP PF07990.12 OAJ28291.1 - 0.077 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DDE_3 PF13358.6 OAJ28292.1 - 2.2e-17 63.2 0.0 3.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ28292.1 - 0.00061 20.3 1.0 0.0021 18.6 0.5 2.3 2 1 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ28292.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Myc_N PF01056.18 OAJ28293.1 - 0.08 12.8 14.0 0.012 15.6 6.4 2.5 1 1 1 2 2 2 0 Myc amino-terminal region LCD1 PF09798.9 OAJ28293.1 - 0.6 8.6 3.2 0.86 8.0 3.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein AT_hook PF02178.19 OAJ28293.1 - 6.4 7.0 10.1 0.51 10.4 2.4 3.1 2 0 0 2 2 2 0 AT hook motif TAF4 PF05236.14 OAJ28294.1 - 0.3 10.8 2.1 0.63 9.7 2.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DCB PF16213.5 OAJ28295.1 - 1.4e-42 145.3 8.1 5.6e-42 143.4 8.1 2.1 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 OAJ28295.1 - 7.7e-41 139.6 7.6 1.6e-40 138.6 0.1 3.9 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 OAJ28295.1 - 2.3e-26 92.2 7.9 5.3e-15 54.7 4.3 3.7 4 1 0 4 4 4 3 C-terminal region of Mon2 protein RTP1_C1 PF10363.9 OAJ28295.1 - 0.0026 17.9 0.1 1.2 9.3 0.0 3.8 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF1981 PF09324.10 OAJ28295.1 - 0.004 17.0 0.0 0.054 13.4 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Urb2 PF10441.9 OAJ28295.1 - 3 7.7 12.4 0.27 11.2 0.2 4.4 5 0 0 5 5 5 0 Urb2/Npa2 family OST3_OST6 PF04756.13 OAJ28296.1 - 2.6e-79 266.6 0.0 3.5e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 OAJ28296.1 - 0.0033 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Cyclin PF08613.11 OAJ28297.1 - 2e-29 103.0 0.9 4.1e-29 102.0 0.6 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ28297.1 - 0.00016 21.4 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain NAD_kinase PF01513.21 OAJ28298.1 - 3.4e-73 246.4 0.0 1.6e-71 240.9 0.0 2.8 1 1 0 1 1 1 1 ATP-NAD kinase DNA_pol_phi PF04931.13 OAJ28298.1 - 0.7 7.9 22.0 1.3 7.0 22.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 OAJ28298.1 - 4.1 5.1 10.1 6.4 4.4 10.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 OAJ28298.1 - 8.2 5.1 9.1 13 4.5 9.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein La PF05383.17 OAJ28299.1 - 2.5e-16 59.5 0.0 4.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 La domain Stn1 PF10451.9 OAJ28300.1 - 1.2e-05 24.5 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 RMI2 PF16100.5 OAJ28300.1 - 0.00093 19.0 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 OAJ28300.1 - 0.0076 16.2 1.2 0.015 15.3 1.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PACT_coil_coil PF10495.9 OAJ28300.1 - 0.16 12.5 0.5 1.4 9.6 0.2 2.4 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein PAP2 PF01569.21 OAJ28301.1 - 3.5e-27 94.8 5.5 7e-27 93.9 5.5 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 OAJ28301.1 - 0.01 15.6 10.0 0.038 13.7 10.0 2.0 1 1 0 1 1 1 1 PAP2 superfamily CoA_binding_2 PF13380.6 OAJ28302.1 - 1.2e-32 112.8 0.1 1.4e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 OAJ28302.1 - 0.0007 20.2 0.0 0.001 19.7 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Flg_new PF09479.10 OAJ28302.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) CNOT11 PF10155.9 OAJ28303.1 - 0.013 15.7 0.0 23 5.2 0.0 3.3 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 11 DUF4231 PF14015.6 OAJ28303.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Phage_integrase PF00589.22 OAJ28304.1 - 5.4e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family adh_short_C2 PF13561.6 OAJ28307.1 - 1.6e-58 198.1 0.2 1.6e-58 198.1 0.2 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ28307.1 - 1.1e-42 145.8 0.3 1.6e-42 145.2 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ28307.1 - 1.5e-12 47.8 0.1 3.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ28307.1 - 8e-05 22.2 0.1 0.00022 20.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 OAJ28307.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHQ_synthase PF01761.20 OAJ28309.1 - 8.3e-43 146.4 0.0 1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 OAJ28309.1 - 0.0038 17.0 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ28310.1 - 0.097 12.4 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase GMC_oxred_N PF00732.19 OAJ28311.1 - 0.024 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase H_lectin PF09458.10 OAJ28312.1 - 5.9e-07 29.6 0.1 2.5e-05 24.3 0.0 3.6 5 0 0 5 5 5 1 H-type lectin domain DUF4384 PF14326.6 OAJ28313.1 - 0.12 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Spc7 PF08317.11 OAJ28313.1 - 0.4 9.5 20.0 0.78 8.6 20.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 OAJ28313.1 - 1.4 8.9 8.7 2.1 8.3 0.6 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Nop14 PF04147.12 OAJ28316.1 - 0.052 11.8 14.2 0.072 11.3 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 OAJ28316.1 - 0.15 10.2 1.7 0.21 9.6 1.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 OAJ28316.1 - 0.15 11.4 10.5 0.25 10.6 10.5 1.4 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 OAJ28316.1 - 0.85 8.3 4.2 1.1 7.9 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 OAJ28316.1 - 2 8.1 7.6 0.27 10.9 2.1 2.1 2 0 0 2 2 2 0 FAM176 family Mcp5_PH PF12814.7 OAJ28317.1 - 2.7e-43 147.0 0.2 9.3e-43 145.2 0.0 2.0 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology SOGA PF11365.8 OAJ28317.1 - 0.013 16.6 0.5 0.19 12.9 0.1 8.3 4 1 3 7 7 7 0 Protein SOGA PH PF00169.29 OAJ28317.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 PH domain GRAB PF10375.9 OAJ28318.1 - 7.6e-06 25.6 1.3 7.6e-06 25.6 1.3 2.8 3 0 0 3 3 3 1 GRIP-related Arf-binding domain Macoilin PF09726.9 OAJ28318.1 - 0.00035 19.3 6.8 0.00035 19.3 6.8 3.6 3 1 1 4 4 3 1 Macoilin family DUF4407 PF14362.6 OAJ28318.1 - 0.002 17.6 17.1 0.002 17.6 17.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 OAJ28318.1 - 0.0022 17.9 1.2 0.0022 17.9 1.2 4.5 3 2 0 5 5 5 1 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 OAJ28318.1 - 0.31 11.3 44.5 0.72 10.1 9.4 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein Serglycin PF04360.12 OAJ28318.1 - 0.62 10.0 0.0 0.62 10.0 0.0 3.7 3 1 1 4 4 3 0 Serglycin Phage_GP20 PF06810.11 OAJ28318.1 - 1.1 9.1 14.1 2.4 7.9 0.1 3.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 Baculo_PEP_C PF04513.12 OAJ28318.1 - 5.3 7.1 13.5 7.4 6.6 0.4 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 OAJ28318.1 - 6.5 6.8 11.5 6.5 6.8 0.9 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 OAJ28318.1 - 8.1 5.7 18.1 0.34 10.2 3.7 2.3 1 1 0 2 2 2 0 FAM76 protein BBP1_C PF15272.6 OAJ28318.1 - 9.1 6.1 22.9 0.21 11.4 14.9 2.3 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Ctr PF04145.15 OAJ28319.1 - 2.8e-15 57.2 0.0 2.7e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 Ctr copper transporter family RRM_1 PF00076.22 OAJ28320.1 - 8.4e-19 67.2 0.0 2.4e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sox17_18_mid PF12067.8 OAJ28320.1 - 0.33 11.0 2.5 0.65 10.1 0.0 2.6 2 0 0 2 2 2 0 Sox 17/18 central domain CBFD_NFYB_HMF PF00808.23 OAJ28321.1 - 1.2e-07 31.9 0.3 2.1e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.10 OAJ28321.1 - 0.0044 16.4 19.7 0.0052 16.2 19.7 1.1 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 OAJ28321.1 - 0.0073 16.4 14.5 0.0092 16.0 14.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.10 OAJ28321.1 - 0.011 15.8 0.9 0.011 15.8 0.9 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC27 PF09507.10 OAJ28321.1 - 0.039 13.3 17.3 0.04 13.3 17.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Histone PF00125.24 OAJ28321.1 - 0.07 13.5 0.2 0.07 13.5 0.2 2.3 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 PIEZO PF15917.5 OAJ28321.1 - 0.31 10.5 6.9 0.46 9.9 6.9 1.2 1 0 0 1 1 1 0 Piezo Afi1 PF07792.12 OAJ28321.1 - 1.1 9.8 8.9 13 6.2 8.9 2.2 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nucleo_P87 PF07267.11 OAJ28322.1 - 0.42 9.4 6.1 0.7 8.7 6.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4011 PF13195.6 OAJ28323.1 - 0.13 12.2 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DDE_1 PF03184.19 OAJ28324.1 - 8.3e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC45 PF02724.14 OAJ28324.1 - 0.37 9.0 20.8 0.44 8.8 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BAF1_ABF1 PF04684.13 OAJ28324.1 - 0.56 9.2 21.0 0.82 8.7 21.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLC12 PF03522.15 OAJ28324.1 - 2.3 7.2 14.0 3.1 6.7 14.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Borrelia_P83 PF05262.11 OAJ28324.1 - 2.5 6.5 32.6 3.6 6.0 32.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP-alpha_N PF04086.13 OAJ28324.1 - 2.6 7.9 24.6 3.9 7.3 24.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPAT_C PF15712.5 OAJ28324.1 - 3.5 6.2 16.5 4.3 5.9 16.5 1.1 1 0 0 1 1 1 0 NPAT C terminus Zip PF02535.22 OAJ28324.1 - 4.3 6.4 4.6 6.3 5.9 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 OAJ28324.1 - 7.5 3.5 10.8 8.9 3.3 10.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 OAJ28324.1 - 8.3 6.4 14.1 13 5.8 14.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SWIB PF02201.18 OAJ28325.1 - 1.2e-21 76.4 0.1 4.6e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain HTH_20 PF12840.7 OAJ28325.1 - 0.068 13.2 0.1 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0160 PF03690.13 OAJ28326.1 - 1.1e-130 435.9 0.0 2.1e-130 435.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RNase_H2-Ydr279 PF09468.10 OAJ28326.1 - 4.9e-10 39.8 0.0 7.8e-09 35.9 0.0 2.5 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 OAJ28326.1 - 6.5e-06 26.3 0.0 5.5e-05 23.3 0.0 2.6 1 1 0 1 1 1 1 Ydr279p protein triple barrel domain DUF4841 PF16129.5 OAJ28326.1 - 0.0071 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4841) DUF572 PF04502.13 OAJ28326.1 - 0.09 12.4 1.7 0.16 11.6 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDE_Tnp_4 PF13359.6 OAJ28327.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Plant_tran PF04827.14 OAJ28327.1 - 8.2e-05 22.3 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein zf-CCCH_4 PF18044.1 OAJ28328.1 - 6.2e-07 29.1 14.1 0.0005 19.8 3.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 OAJ28328.1 - 3.5e-06 27.3 18.6 4.7e-06 26.9 6.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_2 PF12796.7 OAJ28328.1 - 1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ28328.1 - 7.6e-05 22.9 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ28328.1 - 0.00011 22.3 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Torus PF16131.5 OAJ28328.1 - 0.00044 20.9 1.8 0.015 16.0 0.1 2.7 2 0 0 2 2 2 1 Torus domain zf-CCCH PF00642.24 OAJ28328.1 - 0.001 18.9 12.7 0.033 14.1 2.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.30 OAJ28328.1 - 0.0039 17.6 0.0 0.0086 16.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat zf_CCCH_4 PF18345.1 OAJ28328.1 - 0.022 14.8 1.5 0.022 14.8 1.5 2.6 3 0 0 3 3 2 0 Zinc finger domain Ank_4 PF13637.6 OAJ28328.1 - 0.023 15.3 0.0 0.046 14.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) NST1 PF13945.6 OAJ28328.1 - 0.72 9.9 5.7 2.3 8.3 5.7 1.8 1 0 0 1 1 1 0 Salt tolerance down-regulator PPR_2 PF13041.6 OAJ28329.1 - 0.061 13.5 0.0 1.5 9.1 0.0 3.1 4 0 0 4 4 4 0 PPR repeat family Pkinase PF00069.25 OAJ28330.1 - 1e-70 238.1 0.0 1.3e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28330.1 - 3e-31 108.6 0.0 4.6e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ28330.1 - 1e-06 28.3 0.4 0.0049 16.2 0.1 2.3 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 OAJ28330.1 - 0.0011 18.7 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 OAJ28330.1 - 0.04 12.9 0.1 0.057 12.3 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ28330.1 - 0.062 13.2 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family SEEEED PF14797.6 OAJ28330.1 - 0.071 13.3 8.5 0.098 12.8 8.5 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Kdo PF06293.14 OAJ28330.1 - 0.1 11.9 0.1 0.16 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 OAJ28331.1 - 1.5e-19 69.6 0.0 2e-11 43.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ28331.1 - 0.0055 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif SLX9 PF15341.6 OAJ28331.1 - 0.28 11.6 4.4 0.63 10.4 4.4 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Cwf_Cwc_15 PF04889.12 OAJ28332.1 - 0.0027 17.5 4.1 0.047 13.4 0.7 2.4 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 OAJ28332.1 - 0.024 15.0 4.7 0.18 12.2 0.9 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2273 PF10031.9 OAJ28332.1 - 0.061 13.4 2.3 0.13 12.3 2.3 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Otopetrin PF03189.13 OAJ28332.1 - 1.8 7.3 2.7 11 4.8 2.7 1.9 1 1 0 1 1 1 0 Otopetrin CDK2AP PF09806.9 OAJ28332.1 - 3.5 7.6 7.8 0.67 10.0 1.2 2.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 OAJ28332.1 - 7.4 5.3 6.3 1.6 7.5 0.7 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3040 PF11239.8 OAJ28333.1 - 0.63 10.4 3.7 0.94 9.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF4307 PF14155.6 OAJ28333.1 - 4.5 7.1 6.7 12 5.8 6.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Lipase_3 PF01764.25 OAJ28334.1 - 4.3e-13 49.3 0.0 3.5e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Lipase_3 PF01764.25 OAJ28335.1 - 1.8e-06 27.9 0.1 1.4e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 Lipase (class 3) Pex14_N PF04695.13 OAJ28335.1 - 3.5 8.3 17.0 0.34 11.5 3.6 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4147 PF13660.6 OAJ28336.1 - 4.6 6.7 10.5 7.1 6.1 0.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4147) Abhydrolase_3 PF07859.13 OAJ28337.1 - 7.8e-49 166.4 0.1 1.2e-48 165.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ28337.1 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 OAJ28337.1 - 0.11 13.1 2.9 0.23 12.0 2.9 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S3 PF00944.19 OAJ28338.1 - 0.082 12.7 0.8 0.11 12.3 0.8 1.2 1 0 0 1 1 1 0 Alphavirus core protein DUF4813 PF16072.5 OAJ28338.1 - 0.49 10.0 8.1 0.55 9.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) RNase_T PF00929.24 OAJ28340.1 - 1.2e-14 55.2 0.0 1.8e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 OAJ28340.1 - 0.0017 18.1 0.0 0.0057 16.4 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease DUF3246 PF11596.8 OAJ28340.1 - 0.026 14.0 0.7 0.046 13.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Ndc1_Nup PF09531.10 OAJ28340.1 - 0.066 11.9 0.5 0.079 11.6 0.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sporozoite_P67 PF05642.11 OAJ28340.1 - 0.65 8.0 4.5 1.2 7.1 3.8 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.12 OAJ28340.1 - 1.8 7.8 5.6 2.5 7.4 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ28340.1 - 4.4 5.5 6.1 5.9 5.0 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Coq4 PF05019.13 OAJ28341.1 - 5.2e-83 277.7 0.0 6.5e-83 277.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 MMS19_N PF14500.6 OAJ28342.1 - 2.1e-63 214.4 1.9 1.1e-62 212.0 1.9 2.1 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 OAJ28342.1 - 1.6e-28 100.0 0.0 2.8e-26 92.6 0.0 2.9 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal PUL PF08324.11 OAJ28342.1 - 7 5.8 7.5 1.3 8.2 1.3 2.6 2 1 1 3 3 3 0 PUL domain Glyco_H_20C_C PF18088.1 OAJ28343.1 - 1.2e-35 123.2 0.0 1.4e-34 119.7 0.0 2.6 3 0 0 3 3 3 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 OAJ28343.1 - 5.6e-08 32.6 0.0 3.7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain S36_mt PF10937.8 OAJ28343.1 - 0.049 15.2 1.3 0.26 12.9 1.3 2.3 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial SPX PF03105.19 OAJ28343.1 - 1.4 8.8 9.1 0.28 11.0 0.6 2.7 3 1 0 3 3 3 0 SPX domain DUF775 PF05603.12 OAJ28344.1 - 7.9e-44 149.6 0.0 9e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) FmiP_Thoc5 PF09766.9 OAJ28345.1 - 0.0054 16.1 1.8 0.0072 15.7 1.8 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 TPR_14 PF13428.6 OAJ28345.1 - 0.0063 17.2 0.7 9.7 7.3 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3116 PF11313.8 OAJ28345.1 - 0.046 13.6 2.4 0.44 10.4 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) DUF1090 PF06476.12 OAJ28345.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) TPR_2 PF07719.17 OAJ28345.1 - 0.15 12.2 3.3 15 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ28345.1 - 0.17 12.0 3.4 55 4.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28345.1 - 1.6 8.7 4.5 8.1 6.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 OAJ28346.1 - 7.3e-11 42.3 0.0 9.8e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ28346.1 - 6.7e-08 32.9 0.0 9.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ28346.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ28346.1 - 0.00056 19.8 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAJ28346.1 - 0.0029 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAJ28346.1 - 0.0046 17.1 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ28346.1 - 0.0057 17.3 0.0 0.0076 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ28346.1 - 0.0085 16.2 0.3 0.38 10.9 0.3 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Raptor_N PF14538.6 OAJ28347.1 - 1.7e-50 170.8 0.0 3.9e-50 169.6 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 OAJ28347.1 - 4.7e-07 30.4 2.9 1.2 10.1 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat HEAT PF02985.22 OAJ28347.1 - 0.00011 22.1 3.6 0.047 14.0 0.0 5.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 OAJ28347.1 - 0.023 14.8 0.0 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Spt20 PF12090.8 OAJ28347.1 - 0.21 11.1 18.7 0.45 10.1 18.7 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ28347.1 - 0.46 10.4 15.4 0.99 9.3 15.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 OAJ28347.1 - 1.2 8.0 19.6 0.038 12.9 12.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 OAJ28347.1 - 2 8.4 11.7 3.9 7.5 11.7 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MAP65_ASE1 PF03999.12 OAJ28347.1 - 2.2 6.9 7.5 3.3 6.3 7.5 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Roughex PF06020.11 OAJ28347.1 - 2.9 6.9 11.5 5.3 6.0 11.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 OAJ28347.1 - 7.4 5.2 6.3 13 4.4 6.3 1.3 1 0 0 1 1 1 0 Presenilin CLASP_N PF12348.8 OAJ28348.1 - 8.1e-66 221.8 5.1 5.3e-53 179.9 0.3 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 OAJ28348.1 - 0.00044 20.3 7.1 0.083 13.2 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat DUF3361 PF11841.8 OAJ28348.1 - 0.0079 16.1 0.1 0.57 10.1 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 OAJ28348.1 - 0.016 15.2 0.1 4.1 7.4 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 INTS5_C PF14838.6 OAJ28348.1 - 0.15 10.7 0.7 9.2 4.8 0.1 2.2 2 0 0 2 2 2 0 Integrator complex subunit 5 C-terminus HEAT_2 PF13646.6 OAJ28348.1 - 1.6 9.1 16.4 2.2 8.7 0.0 5.8 5 1 1 6 6 6 0 HEAT repeats DPBB_1 PF03330.18 OAJ28349.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ28349.1 - 0.0018 18.1 0.3 0.0031 17.3 0.3 1.3 1 0 0 1 1 1 1 Barwin family Lipase_3 PF01764.25 OAJ28350.1 - 7.8e-12 45.3 0.0 8.5e-10 38.7 0.1 2.6 2 0 0 2 2 2 2 Lipase (class 3) PsaL PF02605.15 OAJ28350.1 - 0.0025 17.5 0.1 0.0079 15.9 0.0 1.8 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI Mito_carr PF00153.27 OAJ28351.1 - 4.7e-47 157.9 4.4 1.2e-14 54.0 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein DSBA PF01323.20 OAJ28353.1 - 1.8e-21 76.8 0.0 2.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Hyr1 PF15789.5 OAJ28353.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 Zn_clus PF00172.18 OAJ28354.1 - 1.9e-08 34.3 2.7 3.6e-08 33.4 2.7 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TBP PF00352.21 OAJ28356.1 - 3.4e-67 222.4 0.2 2.8e-32 110.5 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 OAJ28356.1 - 1.8e-05 24.8 0.1 0.32 11.1 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 OAJ28356.1 - 0.13 12.1 0.1 0.85 9.5 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) OxoDH_E1alpha_N PF12573.8 OAJ28357.1 - 0.089 12.6 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal PEN-2 PF10251.9 OAJ28358.1 - 0.76 10.2 5.1 0.18 12.3 0.9 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase zf-NOSIP PF15906.5 OAJ28359.1 - 9.3e-13 48.1 0.0 2e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 OAJ28359.1 - 9e-06 25.2 14.7 0.00028 20.3 0.2 3.0 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_5 PF14634.6 OAJ28359.1 - 9.9e-06 25.4 11.6 7.9e-05 22.5 1.5 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ28359.1 - 1.2e-05 25.1 14.2 0.0041 16.9 4.9 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ28359.1 - 0.0001 22.6 15.2 0.031 14.6 4.2 3.2 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ28359.1 - 0.00022 21.2 12.6 0.011 15.7 3.1 3.1 3 0 0 3 3 3 2 RING-type zinc-finger FYVE PF01363.21 OAJ28359.1 - 0.00049 20.2 7.2 0.00079 19.5 1.6 2.7 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 OAJ28359.1 - 0.0012 18.7 18.4 0.0054 16.5 5.3 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ28359.1 - 0.016 15.1 21.4 1.8 8.5 6.3 4.1 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ28359.1 - 0.034 14.3 4.0 0.034 14.3 4.0 3.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 OAJ28359.1 - 0.13 12.1 17.0 0.18 11.7 5.2 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ysc84 PF04366.12 OAJ28360.1 - 8.4e-37 125.8 0.6 1.9e-36 124.7 0.6 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_9 PF14604.6 OAJ28360.1 - 3.8e-14 52.3 0.0 7.1e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ28360.1 - 9.6e-12 44.3 0.0 1.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ28360.1 - 2.5e-09 36.7 0.0 5.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AA_permease_2 PF13520.6 OAJ28361.1 - 1.8e-43 149.0 24.4 5.8e-43 147.3 24.4 1.6 1 1 0 1 1 1 1 Amino acid permease ETF_QO PF05187.13 OAJ28363.1 - 2.9e-41 139.8 0.2 4.8e-41 139.1 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 OAJ28363.1 - 8.2e-08 31.7 0.2 5.7e-05 22.4 0.3 2.2 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 OAJ28363.1 - 1.5e-06 28.1 1.3 0.0016 18.1 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ28363.1 - 1.7e-06 28.2 0.0 5.6e-06 26.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ28363.1 - 1.6e-05 24.3 0.0 0.00045 19.5 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 OAJ28363.1 - 7.4e-05 21.6 0.2 0.00012 20.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ28363.1 - 9.6e-05 21.8 0.4 0.00016 21.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ28363.1 - 0.00014 21.2 0.1 0.00033 20.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ28363.1 - 0.00035 19.7 0.0 0.00062 18.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.7 OAJ28363.1 - 0.0042 17.6 1.1 0.01 16.4 1.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 OAJ28363.1 - 0.0051 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ28363.1 - 0.0074 16.8 0.2 0.63 10.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ28363.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 OAJ28363.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_21 PF14697.6 OAJ28363.1 - 0.031 14.4 0.3 0.069 13.3 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 OAJ28363.1 - 0.082 13.0 0.4 0.082 13.0 0.4 1.7 2 0 0 2 2 1 0 4Fe-4S binding domain FAD_binding_3 PF01494.19 OAJ28363.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Fer4_6 PF12837.7 OAJ28363.1 - 1.7 8.8 4.2 0.83 9.8 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Transposase_21 PF02992.14 OAJ28364.1 - 8.7e-05 21.9 0.1 0.00024 20.4 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 Beta_elim_lyase PF01212.21 OAJ28365.1 - 8.8e-61 205.7 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase MTCP1 PF08991.10 OAJ28365.1 - 1.2e-24 86.3 5.6 2.2e-24 85.4 5.6 1.4 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Aminotran_1_2 PF00155.21 OAJ28365.1 - 2.1e-05 23.9 0.0 0.00098 18.4 0.0 2.2 3 0 0 3 3 3 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 OAJ28365.1 - 0.00048 19.5 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family bZIP_1 PF00170.21 OAJ28366.1 - 3.3e-08 33.5 6.8 3.5e-06 27.0 3.7 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 OAJ28366.1 - 7.5e-06 25.9 5.5 7.5e-06 25.9 5.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper RAC_head PF16717.5 OAJ28366.1 - 0.0029 18.6 2.1 0.0055 17.7 2.1 1.4 1 0 0 1 1 1 1 Ribosome-associated complex head domain DUF3450 PF11932.8 OAJ28366.1 - 0.024 13.9 2.0 0.038 13.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PGBA_C PF15437.6 OAJ28366.1 - 0.12 12.8 1.6 0.25 11.8 1.6 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Glutaredoxin2_C PF04399.13 OAJ28366.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain YabA PF06156.13 OAJ28366.1 - 0.55 10.9 1.8 2.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PKcGMP_CC PF16808.5 OAJ28366.1 - 0.74 9.7 3.1 0.54 10.2 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_S20p PF01649.18 OAJ28366.1 - 2.4 8.8 5.3 2.6 8.7 3.1 2.1 2 1 0 2 2 2 0 Ribosomal protein S20 CDC50 PF03381.15 OAJ28368.1 - 6.1e-87 291.7 0.0 7.4e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MHYT PF03707.16 OAJ28369.1 - 2.2e-19 69.4 19.1 3.4e-07 30.3 1.2 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat ANAPC_CDC26 PF10471.9 OAJ28370.1 - 9.7e-05 23.1 10.3 0.0008 20.2 10.3 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 ESCRT-II PF05871.12 OAJ28371.1 - 9.2e-49 165.3 0.0 9.2e-48 162.1 0.0 2.0 1 1 1 2 2 2 2 ESCRT-II complex subunit SelB-wing_2 PF09106.11 OAJ28371.1 - 0.043 14.0 0.0 9.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Fis1_TPR_C PF14853.6 OAJ28372.1 - 7e-24 83.7 0.3 1.1e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 OAJ28372.1 - 2.4e-13 49.5 0.0 4.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 OAJ28372.1 - 0.001 19.0 0.5 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ28372.1 - 0.038 14.6 1.1 0.13 13.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ28372.1 - 0.079 13.5 1.5 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ28372.1 - 0.53 10.2 2.5 1 9.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0016 PF01169.19 OAJ28373.1 - 6e-42 141.9 26.8 4.7e-21 74.9 7.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Ion_trans PF00520.31 OAJ28373.1 - 0.016 14.5 0.1 0.016 14.5 0.1 2.0 2 0 0 2 2 2 0 Ion transport protein MttA_Hcf106 PF02416.16 OAJ28373.1 - 0.15 11.4 1.0 20 4.6 0.0 2.5 2 0 0 2 2 2 0 mttA/Hcf106 family Bac_export_2 PF01312.19 OAJ28373.1 - 0.19 10.9 4.1 0.055 12.7 0.4 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family CobD_Cbib PF03186.13 OAJ28373.1 - 0.48 9.6 4.3 0.21 10.8 0.3 2.0 2 0 0 2 2 2 0 CobD/Cbib protein TrkH PF02386.16 OAJ28374.1 - 9.8e-105 350.9 11.6 2e-103 346.6 2.3 2.1 2 0 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 OAJ28374.1 - 0.048 13.6 5.2 0.11 12.4 5.2 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TB2_DP1_HVA22 PF03134.19 OAJ28374.1 - 9 6.3 10.7 0.17 11.8 2.3 2.6 2 1 0 2 2 2 0 TB2/DP1, HVA22 family FMN_dh PF01070.18 OAJ28376.1 - 4.5e-117 391.0 0.0 5.4e-117 390.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 OAJ28376.1 - 1.5e-20 73.1 0.2 3.8e-20 71.8 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 OAJ28376.1 - 8.4e-06 25.2 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ28376.1 - 0.00055 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 OAJ28376.1 - 0.015 14.7 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 OAJ28376.1 - 0.12 11.6 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Vps5 PF09325.10 OAJ28376.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like F-box-like PF12937.7 OAJ28377.1 - 0.00016 21.5 0.2 0.005 16.7 0.0 3.1 2 1 0 2 2 2 1 F-box-like Sporozoite_P67 PF05642.11 OAJ28377.1 - 0.23 9.5 0.4 0.44 8.6 0.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen F-box PF00646.33 OAJ28377.1 - 0.38 10.7 2.0 4.5 7.3 0.3 2.4 2 0 0 2 2 2 0 F-box domain Aldedh PF00171.22 OAJ28378.1 - 6.4e-178 592.0 0.9 7.2e-178 591.8 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nop14 PF04147.12 OAJ28379.1 - 0.0056 15.0 3.6 0.0087 14.3 3.6 1.2 1 0 0 1 1 1 1 Nop14-like family Myc_N PF01056.18 OAJ28379.1 - 0.15 12.0 5.2 0.26 11.2 4.7 1.3 1 1 0 1 1 1 0 Myc amino-terminal region DUF4050 PF13259.6 OAJ28380.1 - 0.29 11.5 2.8 0.87 9.9 2.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) NAP PF00956.18 OAJ28381.1 - 4e-22 78.7 3.8 5.6e-20 71.6 0.6 2.6 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 OAJ28381.1 - 1.3 9.2 7.4 0.2 11.9 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) dCMP_cyt_deam_1 PF00383.23 OAJ28382.1 - 1.7e-06 27.8 3.6 0.12 12.3 4.9 3.5 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region PET117 PF15786.5 OAJ28383.1 - 1.9e-18 66.5 4.8 8.3e-18 64.4 4.8 1.9 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial TFIIA PF03153.13 OAJ28383.1 - 0.42 10.6 14.3 0.44 10.5 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 OAJ28383.1 - 1.1 8.4 11.1 1.2 8.3 11.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Stm1_N PF09598.10 OAJ28383.1 - 2.4 9.1 14.3 0.39 11.6 10.3 1.8 2 1 0 2 2 2 0 Stm1 zf-Tim10_DDP PF02953.15 OAJ28384.1 - 1.2e-21 76.1 1.8 1.6e-21 75.7 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Flagellin_N PF00669.20 OAJ28384.1 - 0.011 15.8 0.2 0.015 15.4 0.2 1.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FANCI_S3 PF14677.6 OAJ28384.1 - 0.016 15.0 0.6 0.019 14.7 0.6 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 Herpes_UL42 PF02282.16 OAJ28384.1 - 0.045 13.6 0.1 0.059 13.2 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase processivity factor (UL42) Phage_int_SAM_1 PF02899.17 OAJ28385.1 - 0.05 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.6 OAJ28385.1 - 0.055 14.0 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain FAD_binding_4 PF01565.23 OAJ28386.1 - 4e-16 59.0 1.7 7e-16 58.2 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ28386.1 - 3.3e-09 36.7 0.4 7.5e-09 35.6 0.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like WD40 PF00400.32 OAJ28387.1 - 3.6e-08 33.9 9.4 0.12 13.3 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ArfGap PF01412.18 OAJ28388.1 - 1.2e-31 109.2 0.7 2.3e-31 108.3 0.7 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 OAJ28388.1 - 3.3e-08 34.0 0.0 7.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF1724 PF08350.10 OAJ28388.1 - 0.078 13.1 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Phage_integrase PF00589.22 OAJ28390.1 - 5.3e-05 23.1 0.0 6.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family FmiP_Thoc5 PF09766.9 OAJ28392.1 - 1.8e-24 86.7 12.3 2.3e-24 86.4 12.3 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 HAUS-augmin3 PF14932.6 OAJ28392.1 - 5.8 6.4 14.4 6.6 6.2 13.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 HsbA PF12296.8 OAJ28393.1 - 2.2e-14 53.9 3.5 3.7e-14 53.2 3.5 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Ribosomal_L35p PF01632.19 OAJ28394.1 - 4.5e-13 49.5 2.8 9.5e-13 48.4 2.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 HsbA PF12296.8 OAJ28395.1 - 3.2e-13 50.2 6.6 4.4e-13 49.7 6.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A CheZ PF04344.13 OAJ28395.1 - 0.0049 16.8 0.1 0.0059 16.5 0.1 1.2 1 0 0 1 1 1 1 Chemotaxis phosphatase, CheZ FAS_I_H PF18314.1 OAJ28396.1 - 1.1e-69 234.2 0.9 2.1e-69 233.3 0.9 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAJ28396.1 - 7.5e-48 162.9 0.0 2e-47 161.6 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 OAJ28396.1 - 1.2e-22 80.7 1.0 2.5e-22 79.7 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 OAJ28396.1 - 3.1e-17 62.7 0.6 8.4e-17 61.3 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 OAJ28396.1 - 3.4e-14 52.9 0.0 1.1e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 OAJ28396.1 - 3.5e-07 29.9 0.0 5.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ28396.1 - 7.1e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ28396.1 - 0.0015 18.4 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.23 OAJ28396.1 - 0.012 15.0 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain PI3_PI4_kinase PF00454.27 OAJ28397.1 - 2.1e-36 126.1 0.0 4.1e-36 125.1 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase K_oxygenase PF13434.6 OAJ28398.1 - 1.6e-89 300.4 0.0 2.6e-89 299.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ28398.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ28398.1 - 0.00055 19.3 0.0 0.0076 15.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ28398.1 - 0.013 16.1 0.0 0.074 13.6 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ABC_membrane PF00664.23 OAJ28399.1 - 1.2e-96 323.6 23.5 2.4e-50 171.7 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ28399.1 - 9.4e-62 207.5 0.0 3.3e-31 108.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ28399.1 - 1.6e-12 47.4 4.4 6.1e-05 22.6 0.3 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 OAJ28399.1 - 8.4e-07 29.3 0.0 0.015 15.4 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_29 PF13555.6 OAJ28399.1 - 1.9e-06 27.5 0.1 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ28399.1 - 2.3e-06 28.0 0.1 0.45 10.8 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.6 OAJ28399.1 - 4.7e-06 27.1 4.6 0.12 12.7 0.1 4.3 3 2 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.12 OAJ28399.1 - 1.5e-05 24.4 0.0 0.2 10.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.18 OAJ28399.1 - 0.00034 20.1 0.2 0.013 14.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family PRK PF00485.18 OAJ28399.1 - 0.00043 20.1 0.2 0.92 9.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ABC_ATPase PF09818.9 OAJ28399.1 - 0.00072 18.5 0.1 0.39 9.5 0.0 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 OAJ28399.1 - 0.001 19.0 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 OAJ28399.1 - 0.0023 18.5 0.0 1.2 9.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 OAJ28399.1 - 0.0029 17.4 0.1 1.3 8.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 OAJ28399.1 - 0.0032 16.7 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit APS_kinase PF01583.20 OAJ28399.1 - 0.0057 16.6 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.6 OAJ28399.1 - 0.021 15.0 3.1 9.9 6.5 0.2 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAJ28399.1 - 0.11 12.9 0.0 9.6 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ28399.1 - 0.12 12.5 6.2 8.1 6.6 0.1 3.5 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ28399.1 - 0.16 11.7 0.2 51 3.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 OAJ28399.1 - 0.16 11.6 0.0 17 4.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 OAJ28399.1 - 0.22 11.3 0.3 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Helicase_C PF00271.31 OAJ28400.1 - 5e-07 30.0 0.0 2.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ28400.1 - 1.6e-05 24.8 0.0 0.00068 19.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ28400.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3446 PF11928.8 OAJ28401.1 - 0.077 13.3 2.1 0.2 12.0 2.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain Fungal_trans PF04082.18 OAJ28403.1 - 1.7e-18 66.7 0.0 4.2e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ28403.1 - 4e-09 36.4 10.9 6.6e-09 35.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain H_lectin PF09458.10 OAJ28404.1 - 1.6e-17 63.4 0.0 2.6e-08 33.9 0.0 2.9 2 0 0 2 2 2 2 H-type lectin domain DHR10 PF18595.1 OAJ28404.1 - 0.27 11.3 3.6 0.29 11.2 0.1 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Rad51 PF08423.11 OAJ28405.1 - 5.1e-14 52.1 0.1 4e-12 45.9 0.0 3.0 3 0 0 3 3 3 1 Rad51 RecA PF00154.21 OAJ28405.1 - 2.1e-05 24.2 0.1 3.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 OAJ28405.1 - 0.00013 21.6 0.2 0.00044 19.9 0.1 1.9 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 OAJ28405.1 - 0.00014 21.3 0.1 0.00031 20.2 0.1 1.5 1 0 0 1 1 1 1 KaiC HSP20 PF00011.21 OAJ28406.1 - 2.1e-18 66.4 0.8 8.3e-13 48.4 0.2 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 OAJ28406.1 - 7.2e-05 22.3 0.0 0.00043 19.8 0.0 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA EPSP_synthase PF00275.20 OAJ28407.1 - 2.8e-38 131.7 0.0 3.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Pkinase PF00069.25 OAJ28409.1 - 6e-74 248.7 0.0 8.4e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28409.1 - 7.5e-35 120.5 0.0 1.2e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ28409.1 - 0.0063 15.9 0.0 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ28409.1 - 0.0064 15.5 0.0 0.11 11.4 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 OAJ28409.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 TFIIA PF03153.13 OAJ28409.1 - 1.9 8.4 22.0 2.2 8.2 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAJ28409.1 - 3.1 7.8 5.2 4.3 7.3 5.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region L51_S25_CI-B8 PF05047.16 OAJ28411.1 - 6.1e-10 38.9 0.2 9.6e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PEX11 PF05648.14 OAJ28412.1 - 1.6e-13 50.7 0.0 1.1e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Dscam_C PF12355.8 OAJ28412.1 - 0.0029 18.6 0.2 0.0048 17.9 0.2 1.3 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal Abhydrolase_3 PF07859.13 OAJ28413.1 - 6.2e-21 75.2 0.1 1.9e-20 73.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Transposase_21 PF02992.14 OAJ28413.1 - 7.4e-08 31.9 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ28413.1 - 0.0094 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Cutinase PF01083.22 OAJ28413.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Cutinase Dimer_Tnp_hAT PF05699.14 OAJ28414.1 - 3.4e-11 42.8 0.0 7.9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3727 PF12527.8 OAJ28414.1 - 0.11 12.8 2.8 0.27 11.5 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) Chs7 PF12271.8 OAJ28415.1 - 3.3e-11 43.1 0.1 4.3e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone ATP-synt_ab_N PF02874.23 OAJ28415.1 - 5.2e-06 26.9 0.4 8.7e-06 26.2 0.4 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RVT_2 PF07727.14 OAJ28416.1 - 2.2e-59 201.1 0.0 3.1e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ28416.1 - 0.01 15.6 0.5 0.031 14.1 0.5 1.8 1 1 0 1 1 1 0 Reverse transcriptase-like tRNA-synt_1d PF00750.19 OAJ28417.1 - 3.5e-96 322.2 2.0 4.8e-96 321.7 2.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 OAJ28417.1 - 1.1e-20 73.9 0.0 4.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 DALR anticodon binding domain POT1 PF02765.17 OAJ28417.1 - 0.0095 15.8 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 HsbA PF12296.8 OAJ28418.1 - 3.1e-18 66.3 16.7 3.1e-18 66.3 16.7 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1307 PF06998.11 OAJ28418.1 - 0.051 13.6 1.3 0.09 12.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1307) Carbpep_Y_N PF05388.11 OAJ28418.1 - 0.22 12.1 4.0 0.25 11.9 0.7 2.1 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide WAC_Acf1_DNA_bd PF10537.9 OAJ28419.1 - 1.2e-32 112.4 0.0 3.4e-32 111.0 0.0 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 OAJ28419.1 - 2.8e-25 88.7 0.5 2.8e-25 88.7 0.5 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 OAJ28419.1 - 4.5e-11 42.9 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 OAJ28419.1 - 6.9e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 RT_RNaseH_2 PF17919.1 OAJ28422.1 - 2.3e-15 56.4 0.0 4.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ28422.1 - 1.2e-14 54.4 0.0 2.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ28422.1 - 1.8e-12 47.2 0.3 1.8e-12 47.2 0.3 1.7 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 OAJ28422.1 - 4.3e-12 46.3 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 OAJ28422.1 - 2.5e-10 40.2 0.0 4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PH_4 PF15404.6 OAJ28423.1 - 4.2e-28 98.4 0.0 1.9e-27 96.3 0.0 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 OAJ28423.1 - 0.32 11.5 2.1 16 6.0 0.0 3.9 5 0 0 5 5 5 0 PH domain Rad60-SLD PF11976.8 OAJ28424.1 - 3.9e-08 33.0 0.1 0.74 9.7 0.0 5.5 6 0 0 6 6 6 3 Ubiquitin-2 like Rad60 SUMO-like Asp_protease_2 PF13650.6 OAJ28424.1 - 3e-05 24.6 0.1 8.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ28424.1 - 0.00012 22.6 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 OAJ28424.1 - 0.00057 19.6 0.0 2.1 8.1 0.0 4.5 6 0 0 6 6 6 1 Ubiquitin family Ufm1 PF03671.14 OAJ28424.1 - 0.0063 16.6 0.0 0.27 11.4 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin fold modifier 1 protein TUG-UBL1 PF11470.8 OAJ28424.1 - 0.011 15.9 0.1 1 9.6 0.0 2.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain Asp_protease PF09668.10 OAJ28424.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4672 PF15716.5 OAJ28424.1 - 0.34 10.5 2.4 0.67 9.5 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) adh_short PF00106.25 OAJ28426.1 - 6.9e-36 123.5 0.2 1.4e-35 122.6 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ28426.1 - 7.4e-29 101.0 0.6 1e-28 100.5 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ28426.1 - 5.5e-09 36.2 0.2 9.6e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 KR domain UPF1_Zn_bind PF09416.10 OAJ28428.1 - 2.5e-71 238.6 7.2 2.5e-71 238.6 7.2 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 OAJ28428.1 - 1e-58 198.3 0.0 2.8e-58 196.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 OAJ28428.1 - 1.7e-50 172.3 3.3 4.2e-29 102.1 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 OAJ28428.1 - 1.4e-33 114.9 0.0 3e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 OAJ28428.1 - 6.7e-13 48.8 0.0 3.1e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ28428.1 - 2.2e-10 41.0 0.0 7.1e-10 39.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ28428.1 - 1.9e-05 24.5 0.9 0.29 10.8 0.0 3.4 2 1 2 4 4 4 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 OAJ28428.1 - 2.4e-05 24.4 0.0 6.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 OAJ28428.1 - 5.4e-05 22.6 0.4 0.0026 17.0 0.1 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 OAJ28428.1 - 0.00031 20.6 0.1 0.0011 18.8 0.1 2.0 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 OAJ28428.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PIF1 PF05970.14 OAJ28428.1 - 0.022 13.9 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 OAJ28428.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 OAJ28428.1 - 0.095 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 OAJ28428.1 - 0.096 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA PF00004.29 OAJ28428.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 OAJ28428.1 - 0.13 11.7 0.0 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein ADH_zinc_N PF00107.26 OAJ28429.1 - 1.5e-08 34.7 0.0 7.8e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ28429.1 - 1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ28429.1 - 0.00034 20.5 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 OAJ28429.1 - 0.02 16.0 0.0 0.037 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 OAJ28429.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acyl-CoA_dh_2 PF08028.11 OAJ28430.1 - 4e-09 36.8 0.0 7.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ28430.1 - 1.2e-05 25.9 0.1 2.6e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ28430.1 - 0.0026 17.9 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 OAJ28430.1 - 0.013 15.7 1.0 0.031 14.5 0.1 2.1 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain NOPS PF08075.11 OAJ28431.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.2 3 0 0 3 3 3 0 NOPS (NUC059) domain Pkinase PF00069.25 OAJ28433.1 - 1.8e-45 155.4 0.0 4.6e-44 150.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28433.1 - 1e-16 61.0 0.0 2.2e-15 56.7 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ28433.1 - 0.0023 16.8 0.0 0.0055 15.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ28433.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ28433.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ28433.1 - 0.059 13.3 0.7 0.17 11.8 0.6 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mg_trans_NIPA PF05653.14 OAJ28434.1 - 2.6e-26 92.4 9.1 2.9e-15 56.1 2.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Tetraspanin PF00335.20 OAJ28434.1 - 0.099 12.3 0.1 0.099 12.3 0.1 2.4 2 0 0 2 2 2 0 Tetraspanin family Neurensin PF14927.6 OAJ28434.1 - 0.26 11.0 2.5 8.6 6.1 0.2 2.6 2 0 0 2 2 2 0 Neurensin TMEM234 PF10639.9 OAJ28434.1 - 1.4 9.0 5.3 0.27 11.3 0.5 2.2 3 0 0 3 3 3 0 Putative transmembrane family 234 TFIIA PF03153.13 OAJ28435.1 - 2.6 7.9 11.2 1.6 8.6 9.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 OAJ28436.1 - 8.7e-42 143.3 26.3 8.7e-42 143.3 26.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Rdx PF10262.9 OAJ28437.1 - 8.5e-23 80.3 0.0 1.8e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Rdx family Hydrolase_4 PF12146.8 OAJ28438.1 - 1.6e-23 83.2 0.1 3.9e-23 82.0 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ28438.1 - 4.9e-08 33.9 0.4 8.1e-08 33.1 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ28438.1 - 5e-08 32.9 1.3 9.2e-08 32.0 1.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ28439.1 - 6.4e-45 153.3 0.8 4.9e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ28439.1 - 7.7e-10 38.8 0.3 1.9e-09 37.6 0.3 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ28439.1 - 1.7e-08 35.4 0.0 2.5e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ28439.1 - 0.00015 21.5 1.6 0.025 14.2 0.1 3.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 OAJ28439.1 - 0.019 14.6 0.1 0.038 13.6 0.1 1.6 1 1 0 1 1 1 0 Putative esterase Asp2 PF16929.5 OAJ28439.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter DUF2771 PF10969.8 OAJ28439.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) SH3_2 PF07653.17 OAJ28440.1 - 0.00033 20.3 0.0 0.0009 18.9 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAJ28440.1 - 0.0014 18.2 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain MFS_1 PF07690.16 OAJ28441.1 - 2.4e-36 125.4 22.7 1.2e-35 123.1 23.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 OAJ28441.1 - 0.0021 17.5 2.1 0.0021 17.5 2.1 2.5 2 1 0 2 2 2 1 Putative threonine/serine exporter LapA_dom PF06305.11 OAJ28441.1 - 0.42 10.5 0.0 0.42 10.5 0.0 3.2 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain DNA_pol_viral_C PF00336.18 OAJ28443.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Mito_carr PF00153.27 OAJ28445.1 - 2.9e-53 177.8 9.1 4.3e-19 68.2 0.1 4.6 4 0 0 4 4 4 4 Mitochondrial carrier protein DUF2423 PF10338.9 OAJ28446.1 - 4.8e-10 39.5 5.5 8.9e-10 38.6 5.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) DAO PF01266.24 OAJ28447.1 - 2.3e-40 139.3 0.1 2.8e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ28447.1 - 1.2e-05 25.3 0.7 0.0026 17.8 0.0 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ28447.1 - 0.0013 18.9 0.2 0.0036 17.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltrans_RNA PF04452.14 OAJ28447.1 - 0.15 11.4 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 RNA methyltransferase Hira PF07569.11 OAJ28448.1 - 3.5e-35 121.7 0.0 3.3e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split WD40 PF00400.32 OAJ28448.1 - 5.7e-22 77.6 26.4 1.1e-05 26.0 1.1 7.6 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28448.1 - 1.6e-09 37.9 2.1 0.019 15.2 0.0 5.7 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 OAJ28448.1 - 0.00011 21.9 0.7 0.00032 20.4 0.7 1.9 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 OAJ28448.1 - 0.2 10.6 0.8 6.7 5.6 0.0 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 OAJ28448.1 - 0.49 10.4 5.5 10 6.2 0.5 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4604 PF15377.6 OAJ28451.1 - 0.17 12.3 14.2 0.28 11.6 14.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Paramyxo_ncap PF00973.19 OAJ28451.1 - 0.3 9.9 5.4 0.32 9.9 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.14 OAJ28451.1 - 0.71 8.1 11.0 0.76 8.0 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 OAJ28451.1 - 5 7.2 18.0 6.4 6.9 18.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF501 PF04417.12 OAJ28451.1 - 5.1 6.9 9.4 0.15 11.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF501) PPP4R2 PF09184.11 OAJ28451.1 - 6.6 6.2 11.8 9.5 5.7 11.8 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 OAJ28451.1 - 8.3 5.1 6.6 8.2 5.1 6.6 1.2 1 0 0 1 1 1 0 Presenilin IQ PF00612.27 OAJ28452.1 - 0.002 17.8 0.2 0.0045 16.6 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DNA_pol_phi PF04931.13 OAJ28452.1 - 3.8 5.5 11.2 6 4.8 11.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 OAJ28453.1 - 1.6e-08 35.0 0.5 0.029 14.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ28453.1 - 7.1e-08 32.6 2.0 0.038 14.3 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ28453.1 - 9.4e-07 28.7 0.5 0.13 12.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ28453.1 - 1.5e-05 25.4 0.3 0.47 11.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.13 OAJ28453.1 - 0.00082 19.2 0.0 0.0032 17.3 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.30 OAJ28453.1 - 0.055 13.9 10.4 0.51 10.9 0.1 4.2 5 0 0 5 5 5 0 Ankyrin repeat Spc7 PF08317.11 OAJ28453.1 - 0.31 9.9 1.4 0.48 9.2 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FAD_binding_6 PF00970.24 OAJ28455.1 - 3.2e-33 114.0 0.0 5.2e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ28455.1 - 2.3e-30 105.4 0.0 4.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 OAJ28455.1 - 2.8e-06 27.6 0.0 0.00019 21.6 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Adeno_knob PF00541.17 OAJ28455.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) SET PF00856.28 OAJ28456.1 - 8e-18 65.4 1.2 2.2e-16 60.7 0.0 3.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 OAJ28456.1 - 1.1e-14 55.0 10.5 1.1e-14 55.0 10.5 1.8 2 0 0 2 2 2 1 Pre-SET motif preSET_CXC PF18264.1 OAJ28456.1 - 0.024 15.1 2.6 0.024 15.1 2.6 3.1 4 0 0 4 4 4 0 CXC domain eIF3_subunit PF08597.10 OAJ28456.1 - 0.073 13.0 4.5 0.15 12.0 4.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 OAJ28456.1 - 2 6.6 6.2 3.6 5.8 6.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_3 PF01596.17 OAJ28457.1 - 1.1e-46 158.6 0.0 1.6e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 OAJ28457.1 - 9.2e-12 45.9 0.0 1.6e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ28457.1 - 0.054 13.3 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aldo_ket_red PF00248.21 OAJ28458.1 - 8.8e-63 212.2 0.0 1.1e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 OAJ28459.1 - 2.1e-25 89.2 0.0 1.3e-24 86.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ28459.1 - 1.1e-22 80.4 0.0 2.5e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 OAJ28459.1 - 3.8e-08 33.6 0.1 7.1e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ28459.1 - 1.8e-06 27.6 0.0 6.8e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ28459.1 - 0.0094 15.9 0.2 0.083 12.8 0.0 2.4 3 0 0 3 3 3 1 KR domain CAP PF00188.26 OAJ28460.1 - 1.5e-23 84.0 3.3 3e-23 83.0 3.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family BUD22 PF09073.10 OAJ28461.1 - 1.3e-61 209.3 35.2 2.2e-61 208.5 35.2 1.4 1 1 0 1 1 1 1 BUD22 RIO1 PF01163.22 OAJ28462.1 - 6.4e-64 215.0 0.7 6.4e-64 215.0 0.7 2.5 2 1 0 2 2 2 1 RIO1 family SDA1 PF05285.12 OAJ28462.1 - 2.3 7.6 32.2 0.88 8.9 18.9 2.4 2 0 0 2 2 2 0 SDA1 Clathrin_lg_ch PF01086.17 OAJ28463.1 - 1.2e-37 130.2 18.8 9.6e-37 127.2 18.8 2.1 1 1 0 1 1 1 1 Clathrin light chain UCH PF00443.29 OAJ28464.1 - 2.4e-49 168.2 0.0 3.4e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ28464.1 - 1.5e-21 77.4 0.0 4.3e-20 72.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MAM1 PF10434.9 OAJ28464.1 - 0.063 12.9 0.1 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Monopolin complex protein MAM1 PTPlike_phytase PF14566.6 OAJ28465.1 - 4.5e-120 397.2 0.0 1.9e-47 161.3 0.0 4.0 3 1 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase PF00102.27 OAJ28465.1 - 0.0036 16.9 0.1 8.3 5.9 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ28465.1 - 0.0052 16.6 0.0 2.5 7.9 0.0 3.2 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Acyl-thio_N PF12590.8 OAJ28466.1 - 0.0042 17.7 3.1 0.0077 16.8 3.1 1.4 1 0 0 1 1 1 1 Acyl-ATP thioesterase SR-25 PF10500.9 OAJ28466.1 - 0.016 14.9 9.6 0.022 14.4 9.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TcA_TcB_BD PF18276.1 OAJ28466.1 - 0.044 12.9 0.4 0.054 12.6 0.4 1.1 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Saccharop_dh_N PF04455.12 OAJ28466.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 LOR/SDH bifunctional enzyme conserved region PGM_PMM_I PF02878.16 OAJ28468.1 - 7.6e-38 129.3 0.3 1.3e-37 128.6 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 OAJ28468.1 - 2.3e-23 82.8 0.1 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 OAJ28468.1 - 1.2e-09 38.3 0.0 2.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 OAJ28468.1 - 2e-07 31.1 0.2 1.1e-06 28.8 0.1 2.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 OAJ28469.1 - 4.1e-20 71.5 0.0 6.4e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 OAJ28469.1 - 1.8e-18 66.6 0.1 2.2e-17 63.1 0.1 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 OAJ28469.1 - 2.4e-06 27.6 0.0 4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Bd3614-like deaminase EB PF01683.18 OAJ28470.1 - 1.4 9.3 96.9 0.49 10.7 6.2 9.3 2 2 6 8 8 8 0 EB module EMP24_GP25L PF01105.24 OAJ28471.1 - 1.9e-33 115.9 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD VASt PF16016.5 OAJ28472.1 - 3.3e-37 128.3 0.8 8.5e-37 126.9 0.2 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 OAJ28472.1 - 1.2e-26 92.9 0.1 6.4e-26 90.5 0.0 2.0 2 0 0 2 2 2 1 GRAM domain MULE PF10551.9 OAJ28473.1 - 6.4e-21 74.6 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ28473.1 - 2e-06 26.9 0.0 3.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.15 OAJ28473.1 - 5.2e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 MuDR family transposase zf-C2H2_10 PF16588.5 OAJ28473.1 - 0.037 13.8 2.1 0.082 12.7 2.1 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger PhyH PF05721.13 OAJ28475.1 - 4.3e-08 33.7 0.0 1.5e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DIOX_N PF14226.6 OAJ28475.1 - 0.18 12.5 0.0 0.45 11.3 0.0 1.6 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF1325 PF07039.11 OAJ28476.1 - 9e-30 103.5 0.0 1.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.12 OAJ28476.1 - 0.026 15.0 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 0 Agenet domain KH_1 PF00013.29 OAJ28477.1 - 9e-06 25.4 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 KH domain HisKA PF00512.25 OAJ28477.1 - 0.043 13.9 0.0 0.062 13.3 0.0 1.3 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HTH_1 PF00126.27 OAJ28477.1 - 0.083 12.9 0.2 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family TPR_10 PF13374.6 OAJ28478.1 - 8.9e-06 25.4 4.6 0.086 12.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ28478.1 - 0.0005 20.0 0.3 5.9 7.3 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28478.1 - 0.0023 18.2 2.3 0.36 11.2 1.4 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat RHH_4 PF13467.6 OAJ28478.1 - 0.027 14.3 0.2 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain Muted PF14942.6 OAJ28478.1 - 0.034 14.5 1.1 0.069 13.5 0.4 1.8 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ANAPC5 PF12862.7 OAJ28478.1 - 0.12 12.5 3.9 10 6.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 Cofilin_ADF PF00241.20 OAJ28480.1 - 6.8e-39 132.4 0.1 7.6e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LRR_6 PF13516.6 OAJ28481.1 - 8e-16 56.7 30.9 0.0019 18.1 0.1 10.6 11 0 0 11 11 11 5 Leucine Rich repeat GAT PF03127.14 OAJ28481.1 - 0.00015 22.0 0.1 0.004 17.4 0.1 2.7 2 0 0 2 2 2 1 GAT domain LRR_4 PF12799.7 OAJ28481.1 - 0.0015 18.9 21.4 1.8 9.1 0.2 7.2 5 2 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ28481.1 - 0.14 11.9 19.3 19 5.1 0.0 6.5 3 1 3 6 6 6 0 Leucine rich repeat Pinin_SDK_N PF04697.13 OAJ28481.1 - 9.7 6.8 11.9 0.41 11.3 3.7 3.0 2 0 0 2 2 2 0 pinin/SDK conserved region MOSC_N PF03476.16 OAJ28483.1 - 2.1e-20 72.8 0.0 3.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ28483.1 - 6.5e-20 71.5 0.0 3.9e-19 69.0 0.0 2.1 1 1 0 1 1 1 1 MOSC domain SUR7 PF06687.12 OAJ28484.1 - 0.058 13.0 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family 7tm_7 PF08395.12 OAJ28484.1 - 0.14 11.4 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Oxidored_q2 PF00420.24 OAJ28484.1 - 0.29 10.8 3.0 0.34 10.6 0.9 2.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Yip1 PF04893.17 OAJ28484.1 - 3.3 7.4 6.9 7.7 6.2 6.9 1.6 1 0 0 1 1 1 0 Yip1 domain NDC10_II PF16787.5 OAJ28485.1 - 2.2e-43 148.5 0.0 3.8e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_28 PF13518.6 OAJ28485.1 - 0.015 15.4 0.6 0.16 12.2 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 OAJ28485.1 - 0.045 14.1 0.1 0.83 10.0 0.0 2.7 2 0 0 2 2 2 0 Transposase Esterase PF00756.20 OAJ28486.1 - 0.00036 20.3 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Spt20 PF12090.8 OAJ28487.1 - 0.65 9.6 8.1 1 8.9 8.1 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ28487.1 - 5.2 6.9 20.5 6.5 6.6 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CSN8_PSD8_EIF3K PF10075.9 OAJ28488.1 - 5.4e-30 104.3 0.0 8.4e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 OAJ28488.1 - 1e-06 28.3 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Abhydrolase_3 PF07859.13 OAJ28489.1 - 1.1e-14 54.8 0.0 1.5e-11 44.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ28489.1 - 3e-06 26.9 0.0 3.4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 OAJ28489.1 - 0.025 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF5423 PF17461.2 OAJ28489.1 - 0.28 10.0 3.0 0.43 9.4 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) RTA1 PF04479.13 OAJ28490.1 - 7.2e-34 117.2 6.3 7.2e-34 117.2 6.3 1.8 1 1 1 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.21 OAJ28490.1 - 0.027 14.2 9.6 0.48 10.1 9.6 2.3 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus Syndecan PF01034.20 OAJ28490.1 - 4.8 7.2 8.4 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 Syndecan domain HisKA_7TM PF16927.5 OAJ28490.1 - 5.8 6.9 17.8 27 4.7 17.8 2.0 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase RRN3 PF05327.11 OAJ28492.1 - 1.3e-146 489.4 0.0 2.5e-141 472.0 0.0 2.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 ASD2 PF08687.11 OAJ28492.1 - 0.27 10.8 0.8 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Drc1-Sld2 PF11719.8 OAJ28492.1 - 0.53 9.8 11.4 0.031 13.8 5.2 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein Na_trans_assoc PF06512.13 OAJ28492.1 - 3 8.1 10.4 9.8 6.4 10.4 1.8 1 0 0 1 1 1 0 Sodium ion transport-associated Rhodanese PF00581.20 OAJ28494.1 - 1.1e-12 48.4 0.0 2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Serglycin PF04360.12 OAJ28494.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Serglycin ING PF12998.7 OAJ28495.1 - 5e-13 49.5 0.5 8.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ28495.1 - 1.7e-05 24.6 10.6 2.9e-05 23.9 10.6 1.4 1 0 0 1 1 1 1 PHD-finger Menin PF05053.13 OAJ28495.1 - 6.3 5.0 9.7 15 3.8 9.7 1.5 1 0 0 1 1 1 0 Menin Phosphoesterase PF04185.14 OAJ28496.1 - 1.7e-26 93.3 3.2 1.1e-25 90.6 3.2 1.9 1 1 0 1 1 1 1 Phosphoesterase family Calcipressin PF04847.12 OAJ28496.1 - 0.0081 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Calcipressin Histone_H2A_C PF16211.5 OAJ28497.1 - 1.7e-18 66.0 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ28497.1 - 6.7e-17 62.1 0.0 1e-16 61.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ28497.1 - 1.1e-05 25.7 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ28498.1 - 1.6e-22 80.3 0.2 2.1e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ28498.1 - 5e-07 29.9 0.1 9.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAJ28498.1 - 0.00044 20.7 0.0 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 OAJ28498.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 OAJ28498.1 - 0.066 13.2 0.1 0.077 13.0 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein RP-C PF03428.13 OAJ28498.1 - 0.099 12.3 0.2 0.26 10.9 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain FGAR-AT_linker PF18072.1 OAJ28499.1 - 2.2e-19 69.7 0.0 3.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Trehalase PF01204.18 OAJ28500.1 - 1.5e-172 575.0 0.2 1.9e-172 574.7 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 OAJ28500.1 - 2.9e-16 58.9 0.1 4.8e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Cpn60_TCP1 PF00118.24 OAJ28501.1 - 4e-154 513.9 2.2 4.5e-154 513.7 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 OAJ28501.1 - 0.77 9.9 4.2 15 5.7 0.1 3.2 3 0 0 3 3 3 0 Enolase, N-terminal domain GSHPx PF00255.19 OAJ28502.1 - 1.3e-32 111.6 0.1 1.7e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 OAJ28502.1 - 5.4e-05 22.9 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ28502.1 - 0.00041 20.3 0.0 0.0013 18.7 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family GSH_synth_ATP PF03917.17 OAJ28504.1 - 4.1e-111 371.4 0.0 5.5e-110 367.7 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 OAJ28504.1 - 1.6e-28 99.1 0.0 2.5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Collagen PF01391.18 OAJ28505.1 - 5.2e-23 80.6 83.5 4.1e+02 0.8 83.5 3.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_S8e PF01201.22 OAJ28507.1 - 1.1e-47 161.6 0.8 1.5e-47 161.2 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Methyltransf_16 PF10294.9 OAJ28508.1 - 1.8e-12 47.3 0.3 2.7e-10 40.3 0.2 3.0 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 OAJ28508.1 - 0.075 12.6 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 OAJ28508.1 - 0.084 12.6 0.1 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 OAJ28509.1 - 2.2e-26 92.8 0.0 2.7e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28509.1 - 1.2e-12 47.7 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ28509.1 - 1.5e-08 33.8 0.0 2.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sporozoite_P67 PF05642.11 OAJ28509.1 - 1.2 7.2 13.8 1.5 6.8 13.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TB2_DP1_HVA22 PF03134.19 OAJ28510.1 - 3.9e-25 87.6 6.7 3.9e-25 87.6 6.7 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family GrpE PF01025.19 OAJ28511.1 - 2.2e-42 144.5 0.0 3.3e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 GrpE Kdo PF06293.14 OAJ28512.1 - 5.3e-05 22.7 0.0 0.0026 17.1 0.0 2.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ28512.1 - 0.00024 21.1 0.0 0.017 15.1 0.0 2.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 OAJ28512.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 OAJ28512.1 - 0.016 14.5 0.0 5.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase RIO1 PF01163.22 OAJ28512.1 - 0.052 13.2 0.0 5 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DNA_topoisoIV PF00521.20 OAJ28513.1 - 1.1e-128 429.8 0.1 5.2e-128 427.6 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 OAJ28513.1 - 9.8e-49 164.9 0.3 3.6e-48 163.1 0.3 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 OAJ28513.1 - 5.7e-28 97.6 0.4 1.2e-27 96.5 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 OAJ28513.1 - 1.7e-12 47.8 0.0 4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 OAJ28513.1 - 5.4e-08 33.0 0.0 6.6e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 Toprim domain Macoilin PF09726.9 OAJ28513.1 - 0.95 7.9 13.4 1.8 7.0 13.4 1.4 1 0 0 1 1 1 0 Macoilin family GEMIN8 PF15348.6 OAJ28513.1 - 2.3 8.4 6.3 6.9 6.9 6.3 1.8 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RhoGEF PF00621.20 OAJ28514.1 - 7.4e-32 111.1 0.0 1.4e-31 110.1 0.0 1.5 1 1 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 OAJ28514.1 - 4.7e-17 61.9 9.5 9.1e-17 61.0 9.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 OAJ28514.1 - 2.2e-07 31.3 0.0 5.9e-05 23.5 0.0 2.7 3 0 0 3 3 3 2 PH domain PH_13 PF16652.5 OAJ28514.1 - 0.029 14.2 0.1 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain TPP1 PF10341.9 OAJ28515.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Sel1 PF08238.12 OAJ28516.1 - 3.9e-16 59.1 19.5 7.7e-08 32.8 0.3 4.5 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 OAJ28516.1 - 4 7.8 5.8 6.7 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 OAJ28517.1 - 2.4e-32 110.8 1.3 7.3e-17 61.3 1.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ28517.1 - 2.5e-23 82.1 0.0 1.3e-15 57.4 0.1 4.1 2 1 2 4 4 4 3 Myb-like DNA-binding domain Presenilin PF01080.17 OAJ28517.1 - 4.1e-05 22.5 16.6 4.1e-05 22.5 16.6 2.7 3 0 0 3 3 3 1 Presenilin SLIDE PF09111.10 OAJ28517.1 - 0.13 12.3 0.0 0.57 10.2 0.0 3.9 2 2 1 3 3 3 0 SLIDE Spore_III_AB PF09548.10 OAJ28517.1 - 0.14 12.3 0.0 0.14 12.3 0.0 3.2 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) CAC1F_C PF16885.5 OAJ28517.1 - 2.9 7.5 38.9 0.03 14.0 17.8 2.9 3 0 0 3 3 3 0 Voltage-gated calcium channel subunit alpha, C-term PSP1 PF04468.12 OAJ28518.1 - 2.5e-30 104.6 0.3 4.1e-30 103.9 0.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DNA_primase_lrg PF04104.14 OAJ28519.1 - 3e-82 276.0 0.0 3.6e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RAP1 PF07218.11 OAJ28520.1 - 0.0019 16.6 1.4 0.0026 16.1 1.4 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) KH_1 PF00013.29 OAJ28520.1 - 0.0053 16.6 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 KH domain PI3K_1B_p101 PF10486.9 OAJ28520.1 - 0.16 9.7 0.4 0.2 9.4 0.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DEAD PF00270.29 OAJ28521.1 - 6.6e-45 153.0 0.0 1.5e-44 151.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ28521.1 - 9.3e-30 103.2 0.0 2e-27 95.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Borrelia_P83 PF05262.11 OAJ28521.1 - 0.043 12.3 13.4 0.054 12.0 13.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein ERCC3_RAD25_C PF16203.5 OAJ28521.1 - 0.05 12.8 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Zip PF02535.22 OAJ28521.1 - 0.28 10.3 1.6 0.38 9.9 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 OAJ28521.1 - 1.3 7.2 18.4 2 6.6 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 OAJ28522.1 - 0.02 14.6 0.4 0.083 12.7 0.2 2.1 2 0 0 2 2 2 0 Leucine rich repeat RVT_1 PF00078.27 OAJ28524.1 - 3.8e-27 95.3 0.0 9.3e-21 74.4 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) WES_acyltransf PF03007.16 OAJ28525.1 - 1.9e-17 63.9 0.0 3.9e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ28525.1 - 1.7e-08 34.5 0.0 3.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Phage_integrase PF00589.22 OAJ28527.1 - 7.2e-05 22.7 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF4431 PF14485.6 OAJ28527.1 - 0.18 11.6 0.2 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) ERCC4 PF02732.15 OAJ28528.1 - 2.1e-21 76.8 0.0 3.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain UIM PF02809.20 OAJ28528.1 - 0.028 14.3 2.6 0.2 11.7 2.6 2.6 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF515 PF04415.12 OAJ28529.1 - 3.5 5.9 7.9 5.6 5.2 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Aldo_ket_red PF00248.21 OAJ28530.1 - 1.6e-28 99.8 0.0 8.1e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Aldo/keto reductase family Hrs_helical PF12210.8 OAJ28531.1 - 0.076 13.6 3.5 0.13 12.8 3.5 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Dec-1 PF04624.14 OAJ28531.1 - 0.093 12.6 0.3 0.093 12.6 0.3 2.3 2 0 0 2 2 2 0 Dec-1 repeat T3SSipB PF16535.5 OAJ28531.1 - 0.42 11.1 5.0 0.89 10.0 5.0 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB Far-17a_AIG1 PF04750.14 OAJ28532.1 - 1.7e-35 122.2 5.9 2.1e-35 121.9 5.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Inositol_P PF00459.25 OAJ28533.1 - 3.4e-51 174.4 0.1 5.8e-50 170.3 0.1 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family AAA_33 PF13671.6 OAJ28534.1 - 4.5e-16 59.3 2.1 2e-13 50.7 2.1 2.5 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 OAJ28534.1 - 5.6e-08 33.0 0.1 8.4e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain KTI12 PF08433.10 OAJ28534.1 - 2e-07 30.8 1.6 4.6e-06 26.3 0.1 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 OAJ28534.1 - 4.5e-07 29.4 0.0 0.0037 16.6 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin CPT PF07931.12 OAJ28534.1 - 0.0009 19.1 0.1 0.13 12.1 0.0 2.2 1 1 1 2 2 2 2 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 OAJ28534.1 - 0.0039 16.4 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 OAJ28534.1 - 0.0092 16.3 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ28534.1 - 0.016 15.8 2.1 0.48 11.0 2.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 OAJ28534.1 - 0.047 14.1 0.7 5.3 7.5 0.1 2.3 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 OAJ28534.1 - 0.057 13.3 0.3 0.28 11.1 0.0 1.9 1 1 0 2 2 2 0 Adenylylsulphate kinase SKI PF01202.22 OAJ28534.1 - 0.11 12.6 0.5 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 Shikimate kinase Ploopntkinase1 PF18748.1 OAJ28534.1 - 0.21 11.1 0.0 6 6.3 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Exo5 PF09810.9 OAJ28535.1 - 7.9e-56 190.1 0.0 3.1e-49 168.4 0.0 2.6 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease Peptidase_M76 PF09768.9 OAJ28538.1 - 5.8e-51 172.7 0.0 7.6e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 OAJ28538.1 - 0.0023 17.8 0.0 0.0072 16.2 0.0 1.8 2 0 0 2 2 2 1 SprT-like family KAR9 PF08580.10 OAJ28539.1 - 0.84 8.1 7.2 0.98 7.9 7.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIA PF03153.13 OAJ28539.1 - 1.5 8.8 10.0 1.8 8.5 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec1 PF00995.23 OAJ28540.1 - 1.5e-129 433.9 0.0 1.7e-129 433.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family YxiJ PF14176.6 OAJ28540.1 - 0.014 15.9 0.0 0.033 14.7 0.0 1.6 1 0 0 1 1 1 0 YxiJ-like protein UPF0020 PF01170.18 OAJ28541.1 - 5.9e-10 39.2 0.1 3.6e-08 33.3 0.1 2.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 OAJ28541.1 - 9.1e-06 25.5 0.0 0.00015 21.5 0.0 2.6 2 1 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 OAJ28541.1 - 0.0017 17.7 0.0 0.0064 15.8 0.0 1.9 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 OAJ28541.1 - 0.0096 15.6 0.0 0.032 13.9 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_25 PF13649.6 OAJ28541.1 - 0.086 13.6 0.0 0.22 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ28541.1 - 0.17 12.6 0.0 0.44 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 OAJ28542.1 - 1.5e-31 108.0 0.1 2.3e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ28542.1 - 5e-11 42.6 0.1 4.4e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ28542.1 - 0.0085 16.1 0.0 0.64 10.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Mpt_N PF09176.11 OAJ28542.1 - 0.043 14.0 0.1 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal RRM_3 PF08777.11 OAJ28542.1 - 0.054 13.5 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif HA2 PF04408.23 OAJ28544.1 - 1.2e-20 73.7 2.7 1.9e-20 73.2 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ28544.1 - 5.5e-19 68.3 0.1 1.4e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ28544.1 - 6.2e-15 55.5 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ28544.1 - 2e-07 30.9 0.0 5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 OAJ28544.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ28544.1 - 0.00057 20.2 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ28544.1 - 0.00084 19.7 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 OAJ28544.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 OAJ28544.1 - 0.023 13.8 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ28544.1 - 0.08 13.3 1.3 0.14 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 OAJ28544.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAJ28544.1 - 0.17 12.4 1.0 0.54 10.8 0.1 2.3 1 1 1 2 2 2 0 ABC transporter AAA_14 PF13173.6 OAJ28544.1 - 0.83 9.7 5.3 4 7.5 0.1 3.7 3 1 0 3 3 3 0 AAA domain Metallophos PF00149.28 OAJ28545.1 - 1.1e-37 130.6 0.3 1.5e-37 130.1 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ28545.1 - 0.011 16.2 0.2 0.022 15.2 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ28545.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2368 PF10166.9 OAJ28546.1 - 1.3 8.6 5.0 2.8 7.5 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Rtf2 PF04641.12 OAJ28548.1 - 2.2e-55 187.8 0.0 9.1e-55 185.8 0.0 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger tRNA_m1G_MT PF01746.21 OAJ28549.1 - 3.4e-17 62.8 0.3 1.3e-12 47.8 0.0 3.2 3 0 0 3 3 3 3 tRNA (Guanine-1)-methyltransferase GCV_H PF01597.19 OAJ28550.1 - 1.8e-40 137.7 0.9 2.1e-40 137.4 0.9 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 OAJ28550.1 - 0.0014 18.4 0.3 0.0031 17.3 0.3 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme GP70 PF17429.2 OAJ28550.1 - 0.0042 16.9 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Gene product 70 RnfC_N PF13375.6 OAJ28550.1 - 0.0051 16.7 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain TfoX_C PF04994.13 OAJ28550.1 - 0.089 12.9 0.0 2.3 8.3 0.0 2.4 1 1 1 2 2 2 0 TfoX C-terminal domain Syja_N PF02383.18 OAJ28551.1 - 4.8e-87 292.3 0.0 6.1e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain zf-Tim10_DDP PF02953.15 OAJ28552.1 - 1.2e-18 66.5 4.5 1.2e-18 66.5 4.5 1.8 2 1 1 3 3 3 1 Tim10/DDP family zinc finger FA_hydroxylase PF04116.13 OAJ28553.1 - 3.2e-19 69.6 10.3 3.2e-19 69.6 10.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF1772 PF08592.11 OAJ28553.1 - 0.0055 17.0 8.1 0.08 13.3 0.5 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF1772) Smr PF01713.21 OAJ28556.1 - 4e-08 33.5 0.0 3.5e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Smr domain DUF3438 PF11920.8 OAJ28556.1 - 0.061 12.6 0.6 0.11 11.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) ANAPC9 PF12856.7 OAJ28556.1 - 0.5 10.6 2.2 1.4 9.1 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 DUF3535 PF12054.8 OAJ28557.1 - 1.2e-104 351.0 0.0 6.9e-103 345.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 OAJ28557.1 - 1.8e-62 211.1 0.0 2.9e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ28557.1 - 3.8e-16 59.4 0.0 9.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 OAJ28557.1 - 3.9e-13 48.4 31.4 0.045 14.0 0.0 11.2 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 OAJ28557.1 - 0.0007 19.9 17.5 9 6.8 0.1 8.7 9 0 0 9 9 9 1 HEAT repeats HEAT_EZ PF13513.6 OAJ28557.1 - 0.0063 17.0 30.7 2 9.0 0.0 11.4 13 0 0 13 13 13 2 HEAT-like repeat RIX1 PF08167.12 OAJ28557.1 - 0.023 14.5 0.6 2.3 7.9 0.1 2.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 OAJ28557.1 - 0.025 14.2 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 OAJ28557.1 - 0.025 15.2 0.0 0.47 11.1 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region SUIM_assoc PF16619.5 OAJ28557.1 - 0.2 11.7 1.4 1.1 9.4 1.4 2.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Arginosuc_synth PF00764.19 OAJ28558.1 - 3e-157 523.9 0.0 3.6e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 OAJ28558.1 - 0.00016 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 OAJ28558.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase LolA PF03548.15 OAJ28558.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA RNA_POL_M_15KD PF02150.16 OAJ28559.1 - 2e-13 49.9 7.0 3.9e-13 49.0 4.0 2.1 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 OAJ28559.1 - 1.6e-05 24.6 6.0 0.0016 18.2 0.1 3.0 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) GFA PF04828.14 OAJ28559.1 - 4.6e-05 23.7 1.2 0.0063 16.8 0.1 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 OAJ28559.1 - 0.00021 21.2 2.0 0.045 13.8 0.7 2.1 2 0 0 2 2 2 2 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAJ28559.1 - 0.0015 18.6 3.2 0.82 9.8 0.1 2.9 3 0 0 3 3 3 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 OAJ28559.1 - 0.02 14.8 4.8 0.98 9.4 0.1 2.5 3 0 0 3 3 2 0 Transposase zinc-ribbon domain CpXC PF14353.6 OAJ28559.1 - 0.038 14.0 2.5 2.9 8.0 0.1 2.3 1 1 1 2 2 2 0 CpXC protein zf-C4_Topoisom PF01396.19 OAJ28559.1 - 0.08 12.7 2.9 7.3 6.5 1.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger TF_Zn_Ribbon PF08271.12 OAJ28559.1 - 0.12 11.9 2.9 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-ISL3 PF14690.6 OAJ28559.1 - 0.35 11.6 5.5 1.2 9.9 0.0 2.9 2 1 1 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rpr2 PF04032.16 OAJ28559.1 - 0.57 10.5 4.6 3.1 8.2 4.6 2.3 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_Tnp_IS1 PF03811.13 OAJ28559.1 - 0.81 9.5 0.1 0.81 9.5 0.1 2.7 3 0 0 3 3 3 0 InsA N-terminal domain zf-nanos PF05741.13 OAJ28559.1 - 1.1 9.5 5.5 3.1 8.1 0.1 2.5 3 0 0 3 3 2 0 Nanos RNA binding domain zinc_ribbon_9 PF14369.6 OAJ28559.1 - 1.2 9.5 5.6 11 6.4 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon Rubredoxin_2 PF18073.1 OAJ28559.1 - 2.2 8.1 9.6 4.7 7.0 0.6 3.0 3 0 0 3 3 3 0 Rubredoxin metal binding domain Nudix_N_2 PF14803.6 OAJ28559.1 - 2.4 8.1 7.1 21 5.1 0.2 2.5 2 1 0 2 2 2 0 Nudix N-terminal zf-RRN7 PF11781.8 OAJ28559.1 - 2.5 7.9 6.7 2.9 7.6 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-LITAF-like PF10601.9 OAJ28559.1 - 2.9 8.2 6.0 11 6.4 0.1 2.8 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain zf-IS66 PF13005.7 OAJ28559.1 - 3 8.3 6.2 13 6.3 0.1 3.0 2 1 1 3 3 3 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_2 PF13240.6 OAJ28559.1 - 7.6 6.4 10.6 2.7 7.8 0.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ribosomal_L31e PF01198.19 OAJ28560.1 - 6.1e-36 122.5 1.8 1.2e-35 121.6 1.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e Ldh_1_C PF02866.18 OAJ28562.1 - 2.3e-46 157.8 0.0 5.5e-46 156.6 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 OAJ28562.1 - 7.1e-44 149.3 0.1 1e-43 148.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 OAJ28562.1 - 0.0034 16.4 0.0 0.0067 15.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 OAJ28562.1 - 0.015 15.7 0.2 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 OAJ28562.1 - 0.044 13.1 0.6 0.89 8.9 0.0 2.6 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HopA1 PF17914.1 OAJ28562.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 HopA1 effector protein family SAP30_Sin3_bdg PF13867.6 OAJ28564.1 - 9e-07 29.1 0.1 6.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC45 PF02724.14 OAJ28564.1 - 0.0063 14.9 3.1 0.007 14.7 3.1 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 OAJ28564.1 - 0.037 13.4 5.2 0.053 12.9 5.2 1.3 1 0 0 1 1 1 0 SDA1 BSP_II PF05432.11 OAJ28564.1 - 0.073 12.8 8.2 0.21 11.2 2.4 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 OAJ28564.1 - 0.21 9.8 3.6 0.24 9.6 3.6 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 OAJ28564.1 - 1.4 8.7 5.3 0.56 10.0 2.6 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Sas10 PF09368.10 OAJ28566.1 - 1.5e-25 89.4 4.0 1.5e-25 89.4 4.0 2.1 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 OAJ28566.1 - 1e-06 29.3 1.5 2.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fcf2 PF08698.11 OAJ28567.1 - 4.4e-18 65.5 0.2 7.4e-17 61.5 0.0 2.6 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing AAA_15 PF13175.6 OAJ28569.1 - 1.4e-15 57.9 2.8 1.1e-11 45.1 0.0 5.3 1 1 1 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 OAJ28569.1 - 2.5e-15 57.5 60.0 2.5e-15 57.5 60.0 8.3 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.6 OAJ28569.1 - 1.5e-12 47.9 2.8 1.8e-05 24.8 0.0 3.5 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ28569.1 - 4.4e-09 36.1 0.1 4.4e-09 36.1 0.1 3.3 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 OAJ28569.1 - 7.8e-06 26.0 0.1 5.9e-05 23.2 0.0 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 OAJ28569.1 - 4.7e-05 23.1 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 OAJ28569.1 - 0.0015 19.0 0.0 0.0015 19.0 0.0 7.1 3 2 1 4 4 2 1 ABC transporter Roc PF08477.13 OAJ28569.1 - 0.0081 16.4 0.4 0.083 13.1 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TMF_TATA_bd PF12325.8 OAJ28569.1 - 0.01 16.0 12.5 0.01 16.0 12.5 11.4 2 2 9 12 12 9 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 OAJ28569.1 - 0.026 13.2 0.1 0.026 13.2 0.1 7.7 3 1 4 7 7 6 0 AAA domain Spidroin_MaSp PF11260.8 OAJ28569.1 - 0.13 12.6 0.0 0.67 10.3 0.0 2.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 AAA_16 PF13191.6 OAJ28569.1 - 0.4 11.0 0.0 0.4 11.0 0.0 5.2 4 2 1 5 5 3 0 AAA ATPase domain AAA_22 PF13401.6 OAJ28569.1 - 0.63 10.3 0.0 0.63 10.3 0.0 4.0 4 1 0 4 4 3 0 AAA domain AAA_assoc_2 PF16193.5 OAJ28569.1 - 3 8.2 10.7 34 4.8 0.0 5.3 4 0 0 4 4 4 0 AAA C-terminal domain FH2 PF02181.23 OAJ28570.1 - 1.2e-64 218.8 4.0 1.2e-64 218.8 4.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 OAJ28570.1 - 1.5e-44 151.8 0.0 1.5e-44 151.8 0.0 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 OAJ28570.1 - 2.8e-42 144.6 0.3 4e-41 140.8 0.0 2.7 3 0 0 3 3 3 1 Diaphanous FH3 Domain HD_5 PF13487.6 OAJ28570.1 - 0.037 14.3 0.1 1 9.7 0.1 2.7 2 0 0 2 2 2 0 HD domain G-gamma PF00631.22 OAJ28570.1 - 1.4 8.9 4.4 1.3 9.1 0.2 2.8 2 0 0 2 2 2 0 GGL domain TPR_2 PF07719.17 OAJ28571.1 - 1e-07 31.5 4.8 0.11 12.7 0.1 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28571.1 - 5.1e-07 29.2 2.3 0.13 12.2 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ28571.1 - 0.00062 20.4 12.5 0.0021 18.7 2.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat ANTAR PF03861.14 OAJ28571.1 - 0.0049 16.7 1.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 ANTAR domain TPR_11 PF13414.6 OAJ28571.1 - 0.0091 15.7 0.7 0.32 10.7 0.1 2.7 2 0 0 2 2 2 1 TPR repeat zf-RING_4 PF14570.6 OAJ28571.1 - 0.096 12.5 0.7 0.21 11.4 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.6 OAJ28571.1 - 8.7 5.6 21.2 46 3.2 17.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) PFK PF00365.20 OAJ28572.1 - 2.2e-184 611.3 0.2 1.8e-102 342.5 0.2 2.6 2 1 0 2 2 2 2 Phosphofructokinase DUF308 PF03729.13 OAJ28572.1 - 0.28 11.6 1.4 5.8 7.3 0.1 2.9 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Zip PF02535.22 OAJ28573.1 - 3.6e-26 92.2 27.8 1.8e-20 73.5 2.0 3.9 3 1 1 4 4 4 3 ZIP Zinc transporter ATE_C PF04377.15 OAJ28573.1 - 0.12 13.0 0.0 0.57 10.8 0.0 1.9 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus YlaH PF14036.6 OAJ28574.1 - 0.067 13.5 0.8 0.067 13.5 0.8 2.3 3 0 0 3 3 3 0 YlaH-like protein DEP PF00610.21 OAJ28575.1 - 3.7e-16 58.9 0.1 1.4e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) rve_3 PF13683.6 OAJ28575.1 - 0.052 13.3 1.9 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 Integrase core domain Porin_3 PF01459.22 OAJ28577.1 - 1.1e-69 234.9 1.0 1.3e-69 234.7 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rrp15p PF07890.12 OAJ28578.1 - 1.3e-29 103.2 1.2 2.3e-28 99.2 0.0 2.9 2 1 0 2 2 2 1 Rrp15p YL1 PF05764.13 OAJ28578.1 - 2.1e-06 28.0 13.6 4.6e-06 26.9 13.6 1.5 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 OAJ28578.1 - 0.0053 15.1 8.9 0.0078 14.6 8.9 1.2 1 0 0 1 1 1 1 CDC45-like protein TFB6 PF17110.5 OAJ28578.1 - 0.03 14.1 4.0 0.073 12.8 3.1 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TFIIF_alpha PF05793.12 OAJ28578.1 - 0.032 12.8 20.6 0.057 12.0 20.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF5632 PF18646.1 OAJ28578.1 - 0.045 13.8 0.2 0.1 12.7 0.2 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5632) Nop14 PF04147.12 OAJ28578.1 - 0.25 9.5 18.7 0.045 12.0 15.3 1.5 2 0 0 2 2 2 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ28578.1 - 1.1 7.3 33.0 1.9 6.5 33.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 OAJ28578.1 - 1.4 8.2 29.2 0.086 12.2 21.8 2.0 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.12 OAJ28578.1 - 8.9 5.6 25.4 17 4.7 25.4 1.5 1 1 0 1 1 1 0 SDA1 Pro-kuma_activ PF09286.11 OAJ28579.1 - 1.4e-16 61.1 0.0 2.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ28579.1 - 7.5e-11 41.8 5.1 1.6e-10 40.8 5.1 1.5 1 0 0 1 1 1 1 Subtilase family PT PF04886.12 OAJ28580.1 - 0.02 14.5 6.5 16 5.2 0.0 4.2 3 1 0 4 4 4 0 PT repeat Methyltransf_32 PF13679.6 OAJ28580.1 - 0.05 13.6 0.7 0.065 13.2 0.7 1.3 1 0 0 1 1 1 0 Methyltransferase domain ESP PF16590.5 OAJ28580.1 - 0.45 10.8 4.7 3.9 7.8 2.0 2.9 1 1 2 3 3 3 0 Exocrine gland-secreting peptide LHC PF00556.20 OAJ28581.1 - 0.051 13.8 2.2 0.064 13.5 0.2 2.0 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit WD40 PF00400.32 OAJ28583.1 - 0.00052 20.8 1.1 0.053 14.4 0.1 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat Phage_r1t_holin PF16945.5 OAJ28584.1 - 0.19 12.0 2.1 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin TMEM40 PF15817.5 OAJ28584.1 - 4.4 7.1 5.0 4.4 7.1 0.2 3.2 4 0 0 4 4 4 0 Transmembrane protein 40 family SPX PF03105.19 OAJ28585.1 - 1.5e-14 54.8 0.0 1.5e-14 54.8 0.0 4.1 3 1 1 4 4 4 1 SPX domain Phage_integrase PF00589.22 OAJ28585.1 - 9.9e-07 28.7 0.0 0.00011 22.0 0.0 3.0 2 0 0 2 2 2 2 Phage integrase family GRA6 PF05084.13 OAJ28586.1 - 0.012 15.6 1.2 0.012 15.6 1.2 1.8 2 1 0 2 2 2 0 Granule antigen protein (GRA6) TMEM154 PF15102.6 OAJ28586.1 - 0.035 14.0 0.7 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family Amnionless PF14828.6 OAJ28586.1 - 0.097 11.5 0.0 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Amnionless Rab_eff_C PF04698.12 OAJ28586.1 - 0.67 8.2 3.4 0.99 7.6 3.4 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DUF515 PF04415.12 OAJ28586.1 - 1.4 7.2 11.8 2.5 6.4 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Alpha_GJ PF03229.13 OAJ28586.1 - 9.5 6.8 20.8 0.068 13.7 7.8 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J Helicase_C PF00271.31 OAJ28592.1 - 6.3e-06 26.5 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ28592.1 - 0.0055 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-IS66 PF13005.7 OAJ28593.1 - 0.25 11.8 3.6 0.69 10.4 3.6 1.8 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 p450 PF00067.22 OAJ28594.1 - 7.1e-59 199.8 0.0 1.4e-58 198.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PTPS_related PF10131.9 OAJ28595.1 - 0.034 12.5 0.1 0.048 12.0 0.1 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein PNRC PF15365.6 OAJ28595.1 - 0.043 13.6 3.3 0.088 12.6 3.3 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ebp2 PF05890.12 OAJ28600.1 - 8.9e-76 255.0 2.4 8.9e-76 255.0 2.4 1.8 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Hamartin PF04388.12 OAJ28600.1 - 0.25 10.0 1.7 0.37 9.4 1.7 1.3 1 0 0 1 1 1 0 Hamartin protein Nipped-B_C PF12830.7 OAJ28602.1 - 2.6e-49 167.7 1.4 2.6e-49 167.7 1.4 3.0 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.6 OAJ28602.1 - 7.7e-08 32.6 8.8 0.99 9.8 0.1 6.0 4 0 0 4 4 4 4 HEAT repeats Cohesin_HEAT PF12765.7 OAJ28602.1 - 1.4e-07 31.6 0.8 3e-05 24.2 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 OAJ28602.1 - 2.4e-05 24.4 1.1 0.00012 22.2 0.8 2.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ28602.1 - 0.0036 15.9 3.0 0.76 8.3 0.4 3.3 2 2 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ28602.1 - 0.86 10.2 7.9 0.81 10.3 1.6 3.9 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 OAJ28602.1 - 9.9 6.7 7.3 1.1e+02 3.5 0.1 5.0 4 0 0 4 4 4 0 HEAT repeat EVE PF01878.18 OAJ28603.1 - 3.3e-40 137.4 0.0 1.1e-39 135.8 0.0 1.8 1 1 0 1 1 1 1 EVE domain DUF202 PF02656.15 OAJ28604.1 - 1e-06 29.1 7.0 1e-06 29.1 7.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF202) MCM PF00493.23 OAJ28605.1 - 9.7e-98 325.7 0.1 1.4e-97 325.2 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ28605.1 - 9.8e-33 112.7 0.0 1.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ28605.1 - 2.1e-24 85.7 0.9 5.5e-24 84.4 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ28605.1 - 6.1e-16 58.9 0.0 1.7e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ28605.1 - 1.3e-07 31.3 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ28605.1 - 0.0028 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ28605.1 - 0.0071 16.1 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ28605.1 - 0.052 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S26 PF10502.9 OAJ28606.1 - 2.5e-07 30.6 0.0 5.4e-05 23.0 0.0 3.2 3 1 0 3 3 3 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 OAJ28606.1 - 0.00074 19.4 0.0 0.0032 17.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase S24-like Cut8 PF08559.10 OAJ28607.1 - 8.5e-07 28.8 0.0 2.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein Linker_histone PF00538.19 OAJ28608.1 - 6.1e-19 68.2 0.2 6.1e-19 68.2 0.2 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family Forkhead PF00250.18 OAJ28608.1 - 0.03 14.6 0.0 5.8 7.2 0.0 2.3 1 1 1 2 2 2 0 Forkhead domain Peptidase_S15 PF02129.18 OAJ28608.1 - 0.1 12.2 1.2 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) UPF0449 PF15136.6 OAJ28609.1 - 0.11 13.0 0.1 0.48 10.9 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF349 PF03993.12 OAJ28609.1 - 3.6 8.0 8.6 1.2 9.5 3.9 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DAO PF01266.24 OAJ28611.1 - 8.6e-23 81.5 0.2 6.7e-13 48.9 0.0 3.3 2 2 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ28611.1 - 0.00029 21.0 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 OAJ28611.1 - 0.00057 19.1 0.0 0.00083 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 OAJ28611.1 - 0.0017 18.0 0.1 0.0031 17.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 OAJ28611.1 - 0.0031 16.8 0.3 0.0079 15.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ28611.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 OAJ28611.1 - 0.014 15.0 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 OAJ28611.1 - 0.028 15.0 0.6 0.053 14.1 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 OAJ28611.1 - 0.069 12.6 0.1 0.26 10.7 0.1 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 OAJ28611.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ28611.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MIR PF02815.19 OAJ28612.1 - 1.1e-06 28.7 0.0 4.2e-06 26.7 0.0 1.7 1 1 1 2 2 2 1 MIR domain DHC PF09626.10 OAJ28612.1 - 0.19 12.6 0.0 0.28 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihaem cytochrome c Cu_amine_oxid PF01179.20 OAJ28614.1 - 9.9e-155 515.5 0.0 1.2e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 OAJ28614.1 - 4.3e-13 49.5 0.0 9.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 OAJ28614.1 - 0.0097 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CRM1_C PF08767.11 OAJ28615.1 - 2.9e-122 407.8 4.2 3.3e-122 407.7 1.1 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 OAJ28615.1 - 2.1e-39 135.0 2.0 2.1e-39 135.0 2.0 3.8 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 OAJ28615.1 - 1.6e-33 114.1 4.1 5.4e-33 112.5 4.1 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 OAJ28615.1 - 8.2e-29 99.5 0.8 8.2e-29 99.5 0.8 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 OAJ28615.1 - 8.7e-20 69.9 2.5 2.6e-19 68.4 2.5 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 OAJ28615.1 - 6.1e-15 54.9 0.5 2.8e-14 52.8 0.5 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF2294 PF10057.9 OAJ28615.1 - 0.0071 16.5 1.2 5.8 7.1 0.2 3.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2294) DUF1654 PF07867.11 OAJ28615.1 - 0.65 9.8 2.4 12 5.7 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DnaJ PF00226.31 OAJ28616.1 - 3.6e-06 27.0 0.2 5.3e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Ank_2 PF12796.7 OAJ28617.1 - 9e-31 106.3 0.1 2.2e-09 37.8 0.1 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ28617.1 - 7.8e-26 90.1 3.9 7.2e-10 39.2 0.0 5.4 2 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ28617.1 - 4.4e-25 87.4 11.3 1.1e-07 32.0 0.1 7.6 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SPX PF03105.19 OAJ28617.1 - 1.1e-24 88.1 3.2 7.7e-16 59.0 0.3 4.3 3 2 0 3 3 3 2 SPX domain Ank_3 PF13606.6 OAJ28617.1 - 3.7e-21 72.9 4.0 0.00085 19.6 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 OAJ28617.1 - 8.8e-20 70.2 5.9 1.8e-05 24.9 0.0 6.9 6 1 0 6 6 6 3 Ankyrin repeat GDPD PF03009.17 OAJ28617.1 - 8.1e-13 48.7 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-C2H2 PF00096.26 OAJ28618.1 - 6.7e-07 29.4 2.2 0.0024 18.3 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ28618.1 - 2e-06 28.2 3.0 0.0049 17.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 OAJ28618.1 - 0.0002 21.6 2.2 0.11 12.9 0.3 2.2 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 OAJ28618.1 - 0.00071 19.8 5.1 0.014 15.6 0.7 2.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding HypA PF01155.19 OAJ28618.1 - 0.026 14.5 0.2 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ima1_N PF09779.9 OAJ28618.1 - 0.029 15.2 0.0 0.037 14.9 0.0 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-C2H2_9 PF16293.5 OAJ28618.1 - 0.13 12.1 0.2 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) PyrI_C PF02748.15 OAJ28618.1 - 2.2 8.3 3.8 4.5 7.3 0.3 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ribosomal_60s PF00428.19 OAJ28619.1 - 8.5e-27 93.6 6.7 1e-26 93.3 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein THOC2_N PF16134.5 OAJ28619.1 - 0.069 11.8 0.1 0.08 11.6 0.1 1.0 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Ntox27 PF15531.6 OAJ28619.1 - 0.07 13.0 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial toxin 27 Pkinase PF00069.25 OAJ28620.1 - 2.6e-71 240.1 0.0 3.1e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28620.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ28620.1 - 0.0041 16.5 0.0 0.095 12.0 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 OAJ28620.1 - 0.062 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 OAJ28620.1 - 0.066 13.1 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ28620.1 - 0.42 9.5 2.3 2.8 6.8 0.0 2.5 3 0 0 3 3 3 0 Haspin like kinase domain HsbA PF12296.8 OAJ28621.1 - 1.6e-17 64.0 7.3 2.8e-17 63.3 7.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A TPP_enzyme_C PF02775.21 OAJ28621.1 - 0.078 12.8 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cytochrom_B558a PF05038.13 OAJ28622.1 - 0.0081 15.8 1.4 0.35 10.4 0.6 2.8 2 0 0 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF2721 PF11026.8 OAJ28622.1 - 8.1 6.3 13.2 6.6 6.6 0.7 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) ENTH PF01417.20 OAJ28623.1 - 9e-44 148.5 0.1 1.2e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 OAJ28623.1 - 0.0025 16.9 0.2 0.0036 16.4 0.2 1.1 1 0 0 1 1 1 1 ANTH domain DUF2156 PF09924.9 OAJ28623.1 - 0.004 16.2 0.3 0.0057 15.7 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) VHS PF00790.19 OAJ28623.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain TPR_10 PF13374.6 OAJ28624.1 - 3e-29 100.0 35.4 0.00014 21.6 0.1 12.1 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28624.1 - 1.1e-28 99.3 36.1 3.6e-06 27.2 2.0 11.4 6 3 5 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ28624.1 - 1.5e-10 40.4 12.3 5 7.6 0.0 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28624.1 - 7.3e-06 25.6 11.6 0.87 9.5 0.1 9.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ28624.1 - 1.7e-05 24.6 25.5 0.85 9.9 0.1 10.6 12 0 0 12 12 11 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 OAJ28624.1 - 4.3e-05 22.9 5.1 5.3 6.6 0.1 6.6 7 0 0 7 7 7 1 SHNi-TPR ANAPC5 PF12862.7 OAJ28624.1 - 0.00093 19.2 10.6 32 4.7 0.0 7.7 4 2 1 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 OAJ28624.1 - 0.0015 19.0 5.3 0.47 11.0 0.0 5.3 6 1 0 6 6 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ28624.1 - 0.0015 18.6 4.5 2.7 8.1 0.0 5.3 2 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) Arm PF00514.23 OAJ28624.1 - 0.033 14.2 1.2 2.2 8.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 OAJ28624.1 - 0.096 11.4 0.2 17 4.0 0.0 3.9 4 0 0 4 4 4 0 Fungal protein kinase SeqA PF03925.13 OAJ28624.1 - 0.12 12.3 0.0 17 5.4 0.0 4.1 4 1 1 5 5 5 0 SeqA protein C-terminal domain TPR_4 PF07721.14 OAJ28624.1 - 0.64 10.8 11.7 26 5.8 0.6 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat CBP_BcsQ PF06564.12 OAJ28624.1 - 3 7.3 7.1 27 4.1 0.1 4.2 4 0 0 4 4 4 0 Cellulose biosynthesis protein BcsQ TPR_7 PF13176.6 OAJ28624.1 - 3.6 7.8 18.4 0.73 10.0 0.1 7.3 10 0 0 10 10 7 0 Tetratricopeptide repeat PQ-loop PF04193.14 OAJ28625.1 - 5e-31 106.3 13.0 3.4e-18 65.1 1.9 2.9 3 0 0 3 3 3 2 PQ loop repeat CitMHS PF03600.16 OAJ28626.1 - 3.7 6.7 7.3 9.1 5.4 7.3 1.7 1 1 0 1 1 1 0 Citrate transporter DnaJ PF00226.31 OAJ28629.1 - 5.9e-16 58.4 0.4 1.2e-15 57.3 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 OAJ28629.1 - 1e-15 57.6 0.0 1.5e-14 53.8 0.0 2.4 1 1 0 1 1 1 1 Sec63 Brl domain LIDHydrolase PF10230.9 OAJ28629.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SPX PF03105.19 OAJ28630.1 - 0.02 14.8 1.3 0.029 14.3 1.3 1.2 1 0 0 1 1 1 0 SPX domain Utp12 PF04003.12 OAJ28631.1 - 2e-18 66.7 0.6 3.5e-18 65.9 0.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Sds3 PF08598.11 OAJ28632.1 - 3.2e-09 37.1 9.5 3.2e-09 37.1 9.5 2.2 2 0 0 2 2 2 1 Sds3-like Presenilin PF01080.17 OAJ28632.1 - 0.06 12.1 11.3 1.6 7.4 11.3 2.2 2 0 0 2 2 2 0 Presenilin SUZ PF12752.7 OAJ28632.1 - 0.11 13.3 0.2 0.11 13.3 0.2 5.6 5 2 0 5 5 5 0 SUZ domain Baculo_PP31 PF05311.11 OAJ28632.1 - 2.5 7.5 19.2 0.036 13.6 1.7 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) EPL1 PF10513.9 OAJ28632.1 - 5.1 7.5 15.1 0.12 12.8 7.6 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Peptidase_C12 PF01088.21 OAJ28633.1 - 1e-52 179.0 0.0 1.2e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PX PF00787.24 OAJ28634.1 - 1.6e-24 86.0 0.1 1.6e-24 86.0 0.1 1.8 2 0 0 2 2 2 1 PX domain eIF-3_zeta PF05091.12 OAJ28634.1 - 1.5 7.7 15.7 2.6 6.9 15.7 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 OAJ28634.1 - 4.5 7.0 11.8 6.5 6.5 11.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 OAJ28635.1 - 1.5 8.1 10.5 1.6 8.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 OAJ28635.1 - 3 6.3 10.4 3.3 6.1 10.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF5313 PF17240.2 OAJ28636.1 - 0.038 14.4 0.3 0.06 13.8 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Nnf1 PF03980.14 OAJ28636.1 - 0.088 13.2 1.8 0.13 12.6 1.8 1.2 1 0 0 1 1 1 0 Nnf1 DUF5635 PF18685.1 OAJ28636.1 - 3.1 7.8 5.3 1.5 8.8 0.9 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5635) Peptidase_S9 PF00326.21 OAJ28637.1 - 1.6e-06 27.8 0.1 3.9e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ28637.1 - 0.0012 18.2 0.1 0.0053 16.0 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ28637.1 - 0.011 15.5 0.1 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 OAJ28637.1 - 0.048 12.8 0.1 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Esterase PF00756.20 OAJ28639.1 - 1.9e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 OAJ28639.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DsbC_N PF10411.9 OAJ28639.1 - 0.06 12.8 0.1 0.25 10.8 0.0 2.0 1 1 1 2 2 2 0 Disulfide bond isomerase protein N-terminus DUF4189 PF13827.6 OAJ28639.1 - 0.13 12.8 0.3 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4189) Pterin_4a PF01329.19 OAJ28640.1 - 1.2e-24 86.3 0.1 1.6e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase KSHV_K8 PF07188.11 OAJ28640.1 - 0.081 12.3 0.1 0.081 12.3 0.1 1.1 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein UPF0086 PF01868.16 OAJ28641.1 - 1.7e-16 59.9 0.0 6.3e-16 58.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function UPF0086 PAP_PilO PF06864.12 OAJ28641.1 - 0.15 10.8 2.5 1.6 7.5 0.2 2.5 3 0 0 3 3 3 0 Pilin accessory protein (PilO) Sdh5 PF03937.16 OAJ28643.1 - 1.3e-24 86.0 0.5 7.9e-24 83.4 0.2 2.1 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase DUF1674 PF07896.12 OAJ28643.1 - 0.00093 19.6 0.6 0.0045 17.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) GIY-YIG PF01541.24 OAJ28645.1 - 3.1e-10 40.2 0.0 1.7e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain Macoilin PF09726.9 OAJ28645.1 - 1.3 7.4 12.2 2.5 6.5 12.2 1.4 1 0 0 1 1 1 0 Macoilin family Cyclin PF08613.11 OAJ28646.1 - 5.4e-07 30.1 0.0 1.6e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Cyclin TFIIA PF03153.13 OAJ28646.1 - 4.2 7.2 32.0 0.31 11.0 25.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1275 PF06912.11 OAJ28647.1 - 1e-29 103.8 14.3 1.3e-29 103.5 14.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) BT1 PF03092.16 OAJ28647.1 - 0.11 10.7 5.8 0.097 10.9 0.7 2.3 2 0 0 2 2 2 0 BT1 family Collectrin PF16959.5 OAJ28647.1 - 0.17 11.6 1.2 0.28 10.9 1.2 1.3 1 0 0 1 1 1 0 Renal amino acid transporter YwiC PF14256.6 OAJ28647.1 - 0.19 12.1 4.8 0.43 10.9 4.8 1.7 1 1 0 1 1 1 0 YwiC-like protein Mito_carr PF00153.27 OAJ28648.1 - 1.8e-47 159.2 2.9 6.3e-16 58.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TrkH PF02386.16 OAJ28649.1 - 2.5e-104 349.5 11.9 2.7e-102 342.8 2.2 2.1 2 0 0 2 2 2 2 Cation transport protein SRP-alpha_N PF04086.13 OAJ28649.1 - 0.022 14.7 2.4 0.042 13.8 2.4 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TB2_DP1_HVA22 PF03134.19 OAJ28649.1 - 0.24 11.4 3.9 0.11 12.4 0.4 2.3 2 0 0 2 2 2 0 TB2/DP1, HVA22 family ERO1 PF04137.15 OAJ28650.1 - 1.7e-121 405.7 0.0 4.7e-120 401.0 0.0 2.0 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) LCAT PF02450.15 OAJ28651.1 - 5.4e-89 299.1 0.1 1.7e-87 294.2 0.1 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase TRAPP PF04051.16 OAJ28652.1 - 5.8e-32 110.4 0.0 1.6e-31 109.0 0.0 1.6 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component ATP-grasp_2 PF08442.10 OAJ28653.1 - 8.4e-67 224.7 0.3 1.4e-66 223.9 0.1 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 OAJ28653.1 - 2.4e-23 82.7 0.8 4.3e-23 81.8 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 OAJ28653.1 - 2.3e-11 43.6 0.1 4.4e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAJ28653.1 - 0.0014 18.5 0.1 0.0033 17.2 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 OAJ28653.1 - 0.031 13.8 0.1 0.079 12.4 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 OAJ28653.1 - 0.096 12.3 0.1 0.27 10.8 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain ApbA PF02558.16 OAJ28654.1 - 5.8e-27 94.2 0.0 9.3e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 OAJ28654.1 - 6.2e-27 94.3 0.0 1.6e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_3 PF01494.19 OAJ28654.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain TAF PF02969.17 OAJ28655.1 - 1.4e-21 76.4 0.0 3.9e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 OAJ28655.1 - 2.9e-14 53.1 0.0 8.2e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 OAJ28655.1 - 5.4e-05 23.6 0.8 0.00012 22.5 0.5 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 OAJ28655.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Spt5_N PF11942.8 OAJ28655.1 - 0.045 14.7 5.1 0.38 11.8 1.6 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF4611 PF15387.6 OAJ28655.1 - 0.11 12.8 1.1 3.3 8.0 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) RRM_1 PF00076.22 OAJ28656.1 - 2.6e-15 56.0 0.0 9.1e-07 28.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ28656.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif NP1-WLL PF11733.8 OAJ28657.1 - 0.54 10.0 4.7 1.1 9.0 4.7 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 Cation_ATPase_C PF00689.21 OAJ28659.1 - 1.2e-48 165.2 4.1 1.9e-47 161.4 1.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ28659.1 - 1.8e-48 164.4 4.8 1.9e-48 164.4 1.6 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ28659.1 - 2.4e-25 90.1 2.9 6.6e-25 88.6 2.9 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ28659.1 - 1e-19 70.0 0.0 2.6e-19 68.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ28659.1 - 3.3e-17 62.3 0.0 6.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 OAJ28659.1 - 9.3e-07 29.4 0.0 2.4e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ28659.1 - 2.3e-06 27.6 0.7 4.2e-05 23.4 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TraL PF07178.11 OAJ28659.1 - 0.17 12.4 0.9 3.1 8.3 0.1 2.9 2 0 0 2 2 2 0 TraL protein DUF2890 PF11081.8 OAJ28660.1 - 0.2 11.8 5.7 0.27 11.3 5.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PHD PF00628.29 OAJ28661.1 - 4e-07 29.8 8.4 4e-07 29.8 8.4 1.9 2 0 0 2 2 2 1 PHD-finger Xpo1 PF08389.12 OAJ28662.1 - 3.8e-26 91.9 0.0 3e-24 85.8 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 OAJ28662.1 - 8.6e-08 32.0 0.1 2.9e-07 30.3 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 OAJ28662.1 - 0.0012 19.0 0.0 0.0086 16.2 0.0 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 OAJ28662.1 - 0.0017 18.5 0.1 0.42 10.7 0.0 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein RasGEF_N_2 PF14663.6 OAJ28662.1 - 0.013 15.9 0.2 0.9 10.0 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2489 PF10675.9 OAJ28662.1 - 0.023 14.6 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) HEAT PF02985.22 OAJ28662.1 - 0.049 13.9 2.5 0.3 11.5 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat 2_5_RNA_ligase2 PF13563.6 OAJ28662.1 - 0.074 13.0 0.9 0.25 11.3 0.1 2.4 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily TetR_C_22 PF17928.1 OAJ28662.1 - 0.089 13.1 0.8 9.9 6.5 0.0 3.8 4 1 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain FerA PF08165.11 OAJ28662.1 - 0.1 12.6 0.1 0.47 10.4 0.1 2.2 1 0 0 1 1 1 0 FerA (NUC095) domain HEAT_EZ PF13513.6 OAJ28662.1 - 2 9.0 10.9 4.2 8.0 0.0 5.7 5 1 1 6 6 6 0 HEAT-like repeat Indigoidine_A PF04227.12 OAJ28663.1 - 2.2e-109 365.3 1.5 4e-109 364.5 1.5 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 OAJ28663.1 - 1.5e-18 67.2 1.9 8.9e-10 38.4 0.2 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Sec10 PF07393.11 OAJ28664.1 - 1.7e-238 793.7 0.0 2.1e-238 793.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Spc7 PF08317.11 OAJ28664.1 - 0.0037 16.2 0.1 0.0067 15.3 0.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF1664 PF07889.12 OAJ28664.1 - 0.019 15.0 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 OAJ28664.1 - 0.13 12.4 0.2 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF812 PF05667.11 OAJ28664.1 - 0.3 9.9 2.5 0.74 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DNA_ligase_A_M PF01068.21 OAJ28665.1 - 4.1e-38 131.1 0.0 1.2e-25 90.3 0.0 3.7 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ28665.1 - 1.9e-30 106.4 0.0 4.5e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAJ28665.1 - 3.6e-17 62.8 0.1 1.4e-16 60.9 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Presenilin PF01080.17 OAJ28665.1 - 0.32 9.7 1.4 0.55 8.9 1.4 1.4 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 OAJ28666.1 - 7.2e-20 70.9 6.8 5.3e-15 55.3 3.8 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ28666.1 - 6.1e-14 52.0 7.5 1.1e-09 38.4 0.8 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 OAJ28666.1 - 9.5e-05 22.7 6.8 0.028 14.8 0.0 3.2 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ28666.1 - 0.021 15.0 0.2 1.7 8.9 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 ANAPC4 PF12896.7 OAJ28666.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 Cwf_Cwc_15 PF04889.12 OAJ28666.1 - 3 7.5 36.4 2.1 8.0 6.3 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 OAJ28667.1 - 0.0016 16.9 0.7 0.0016 16.9 0.7 1.7 2 0 0 2 2 2 1 CDC45-like protein YL1 PF05764.13 OAJ28667.1 - 0.0045 17.1 0.4 0.0045 17.1 0.4 1.8 2 0 0 2 2 2 1 YL1 nuclear protein GST_C_3 PF14497.6 OAJ28669.1 - 7.2e-26 90.3 0.1 1.4e-25 89.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ28669.1 - 8.5e-06 25.9 0.0 1.6e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ28669.1 - 0.00027 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RhoGEF PF00621.20 OAJ28670.1 - 3.8e-12 46.8 0.0 5.1e-08 33.4 0.0 2.8 2 1 0 2 2 2 2 RhoGEF domain PH PF00169.29 OAJ28670.1 - 0.0032 17.9 0.0 0.006 17.1 0.0 1.4 1 0 0 1 1 1 1 PH domain La PF05383.17 OAJ28671.1 - 6.4e-15 55.0 0.2 2.5e-14 53.1 0.2 2.0 1 1 0 1 1 1 1 La domain RRM_1 PF00076.22 OAJ28671.1 - 1.7e-05 24.5 0.1 4.1e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ28671.1 - 0.11 12.5 0.1 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.28 OAJ28672.1 - 3.3e-23 81.6 0.3 3.6e-23 81.5 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 OAJ28672.1 - 0.11 12.7 0.0 0.37 10.9 0.0 1.8 1 1 1 2 2 2 0 V-ATPase subunit H HlyIII PF03006.20 OAJ28673.1 - 1.1e-49 169.1 20.0 1.4e-49 168.8 20.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related ABC2_membrane_5 PF13346.6 OAJ28673.1 - 5 6.6 7.8 14 5.2 5.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Arrestin_C PF02752.22 OAJ28674.1 - 0.00027 21.4 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ28674.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SOUL PF04832.12 OAJ28674.1 - 0.086 13.0 0.2 0.3 11.3 0.2 1.9 1 0 0 1 1 1 0 SOUL heme-binding protein Alpha-E PF04168.12 OAJ28675.1 - 0.057 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. TFIIA_gamma_N PF02268.16 OAJ28676.1 - 1.9e-24 85.4 0.1 2.4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 OAJ28676.1 - 1.1e-19 70.3 0.2 1.6e-19 69.8 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit NCBP3 PF10309.9 OAJ28677.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 OAJ28677.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain CDK2AP PF09806.9 OAJ28677.1 - 6.8 6.7 6.8 7.2 6.6 5.6 1.6 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MAPEG PF01124.18 OAJ28679.1 - 5e-24 84.7 1.4 5.9e-24 84.4 1.4 1.1 1 0 0 1 1 1 1 MAPEG family TPR_10 PF13374.6 OAJ28681.1 - 3e-09 36.4 16.5 0.18 11.7 1.4 7.7 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28681.1 - 8.1e-09 35.6 33.7 0.00033 20.9 6.4 7.2 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ28681.1 - 0.00016 22.2 15.6 4.8 8.3 1.3 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28681.1 - 0.00032 20.4 11.5 7.8 6.5 0.6 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 OAJ28681.1 - 0.0022 16.8 3.4 0.39 9.4 0.1 3.5 3 2 0 4 4 4 1 Fungal protein kinase ANAPC5 PF12862.7 OAJ28681.1 - 0.0025 17.9 14.1 7.7 6.7 0.2 6.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 OAJ28681.1 - 0.0025 17.2 7.1 1.4 8.4 0.1 4.3 5 0 0 5 5 5 2 SHNi-TPR TPR_2 PF07719.17 OAJ28681.1 - 0.0039 17.2 24.7 11 6.4 0.7 8.5 8 2 1 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ28681.1 - 0.0044 17.1 6.8 0.14 12.2 0.7 3.6 1 1 3 4 4 4 3 Domain of Unknown Function (DUF3856) TPR_8 PF13181.6 OAJ28681.1 - 0.076 13.3 15.2 8.4 6.9 2.0 6.2 6 1 0 6 6 6 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 OAJ28682.1 - 0.0067 16.2 9.4 0.0067 16.2 9.4 2.2 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DUF3774 PF12609.8 OAJ28682.1 - 0.055 14.5 2.1 0.055 14.5 2.1 3.6 2 1 0 2 2 2 0 Wound-induced protein SLC12 PF03522.15 OAJ28682.1 - 0.61 9.0 8.9 0.099 11.7 1.8 2.0 2 0 0 2 2 2 0 Solute carrier family 12 DinB_2 PF12867.7 OAJ28682.1 - 1 9.9 4.7 7.3 7.1 0.1 2.7 3 0 0 3 3 3 0 DinB superfamily Presenilin PF01080.17 OAJ28682.1 - 1.9 7.2 9.3 0.031 13.0 1.3 1.8 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.6 OAJ28682.1 - 4.2 7.3 14.7 0.17 11.9 4.2 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF4692 PF15763.5 OAJ28682.1 - 5.5 7.4 13.6 13 6.2 13.6 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) HA2 PF04408.23 OAJ28685.1 - 2.3e-19 69.6 0.0 4.6e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ28685.1 - 4.5e-19 68.6 0.0 1.6e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ28685.1 - 8.2e-16 58.3 0.0 1.7e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ28685.1 - 1.2e-05 25.2 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ28685.1 - 1.4e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ28685.1 - 0.0077 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ28685.1 - 0.029 14.4 0.0 0.29 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ28685.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 OAJ28685.1 - 0.14 11.6 0.0 0.77 9.2 0.0 2.2 2 1 1 3 3 3 0 PhoH-like protein LAG1-DNAbind PF09271.11 OAJ28686.1 - 6.2e-22 78.8 0.0 8.5e-21 75.2 0.0 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 OAJ28686.1 - 2.6e-14 53.7 0.0 5.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF2205 PF10224.9 OAJ28687.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 OAJ28687.1 - 0.0015 19.2 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 Initiation control protein YabA TACC_C PF05010.14 OAJ28687.1 - 0.0091 15.8 0.1 0.01 15.6 0.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Metallophos PF00149.28 OAJ28688.1 - 8.2e-36 124.4 0.1 1.3e-35 123.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ28688.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 OAJ28688.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) V-ATPase_G PF03179.15 OAJ28689.1 - 4.7e-21 75.3 11.8 5.1e-21 75.2 11.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 OAJ28689.1 - 0.0032 17.6 11.2 0.0033 17.5 11.2 1.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) Ntox34 PF15606.6 OAJ28689.1 - 0.046 13.8 0.4 0.055 13.6 0.3 1.3 1 1 0 1 1 1 0 Bacterial toxin 34 TFA2_Winged_2 PF18121.1 OAJ28689.1 - 0.064 13.0 1.1 0.081 12.6 1.1 1.4 1 1 0 1 1 1 0 TFA2 Winged helix domain 2 DUF3552 PF12072.8 OAJ28689.1 - 0.067 12.6 9.6 0.067 12.6 9.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2461 PF09365.10 OAJ28690.1 - 5.3e-59 199.7 0.1 7.6e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) Pkinase PF00069.25 OAJ28691.1 - 8.4e-59 199.1 0.0 8.6e-35 120.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28691.1 - 2.1e-22 79.7 0.0 2.8e-20 72.7 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ28691.1 - 0.22 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 OAJ28692.1 - 0.0058 17.5 12.1 0.22 12.5 0.1 5.6 6 0 0 6 6 6 1 WD domain, G-beta repeat SPX PF03105.19 OAJ28692.1 - 0.78 9.6 12.9 2.2 8.1 0.3 2.8 2 1 0 2 2 2 0 SPX domain Apt1 PF10351.9 OAJ28692.1 - 3.2 6.5 4.1 19 4.0 0.3 2.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain FAD_binding_3 PF01494.19 OAJ28693.1 - 1.4e-68 231.7 0.0 1.8e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ28693.1 - 1.2e-05 24.7 0.0 0.00025 20.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 OAJ28693.1 - 0.00037 20.6 0.0 0.00065 19.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAJ28693.1 - 0.00045 20.4 0.1 0.0013 18.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 OAJ28693.1 - 0.00053 20.5 0.1 0.0018 18.8 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ28693.1 - 0.00055 19.6 1.2 0.037 13.6 0.3 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ28693.1 - 0.0017 17.6 0.0 0.0029 16.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 OAJ28693.1 - 0.0027 16.9 0.3 0.0049 16.0 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 OAJ28693.1 - 0.0033 16.5 0.4 0.006 15.7 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 OAJ28693.1 - 0.0053 15.5 0.3 0.0084 14.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 OAJ28693.1 - 0.032 13.3 0.4 0.05 12.7 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 OAJ28693.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ28693.1 - 0.28 10.5 0.3 0.41 9.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.25 OAJ28694.1 - 8.1e-32 110.3 1.9 1.3e-31 109.6 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ28694.1 - 9.5e-25 87.5 1.3 1.4e-24 87.0 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ28694.1 - 9.7e-09 35.4 0.5 1.4e-08 34.9 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 OAJ28694.1 - 6.1e-06 26.3 1.0 7.7e-06 25.9 1.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ28694.1 - 9.3e-06 25.3 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ28694.1 - 0.0045 16.4 0.1 0.014 14.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 OAJ28694.1 - 0.077 13.3 0.4 0.14 12.4 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_2 PF00891.18 OAJ28695.1 - 1.2e-24 86.7 0.0 3.8e-24 85.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 OAJ28695.1 - 0.014 15.2 0.2 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 IclR helix-turn-helix domain MTS PF05175.14 OAJ28695.1 - 0.061 12.9 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 OAJ28695.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase HTH_31 PF13560.6 OAJ28695.1 - 0.13 12.7 0.7 2.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 OAJ28696.1 - 2e-50 171.7 0.0 2.3e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GSDH PF07995.11 OAJ28697.1 - 4.2e-05 23.0 0.1 0.00012 21.5 0.1 1.7 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Fungal_trans PF04082.18 OAJ28698.1 - 1.1e-06 28.0 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ28698.1 - 2.4e-06 27.5 10.4 3.9e-06 26.9 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2722 PF10846.8 OAJ28699.1 - 0.0007 18.7 20.4 0.00093 18.3 20.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MAP65_ASE1 PF03999.12 OAJ28699.1 - 0.0023 16.7 13.5 0.0025 16.6 13.5 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) TFIIA PF03153.13 OAJ28699.1 - 0.0087 16.1 24.0 0.01 15.9 24.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 OAJ28699.1 - 0.014 12.6 13.8 0.017 12.3 13.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 OAJ28699.1 - 0.024 14.2 28.5 0.03 14.0 28.5 1.1 1 0 0 1 1 1 0 Spt20 family ANAPC_CDC26 PF10471.9 OAJ28699.1 - 0.035 14.9 23.5 0.051 14.4 23.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 CTNNB1_binding PF08347.11 OAJ28699.1 - 0.13 12.4 9.9 0.16 12.2 9.9 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding TERB2 PF15101.6 OAJ28699.1 - 0.14 12.2 11.2 0.16 12.0 11.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Band_3_cyto PF07565.13 OAJ28699.1 - 0.19 11.5 5.8 0.22 11.3 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4718 PF15842.5 OAJ28699.1 - 0.33 10.7 7.3 0.42 10.4 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) eIF-3_zeta PF05091.12 OAJ28699.1 - 0.36 9.7 10.1 0.42 9.5 10.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 OAJ28699.1 - 0.39 9.5 7.3 0.44 9.3 7.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 OAJ28699.1 - 0.43 10.8 5.4 0.52 10.5 5.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 OAJ28699.1 - 0.43 8.4 5.8 0.44 8.4 5.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 OAJ28699.1 - 0.45 9.7 3.0 0.5 9.5 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Lin-8 PF03353.15 OAJ28699.1 - 0.63 9.5 14.9 0.71 9.4 14.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist UPF0560 PF10577.9 OAJ28699.1 - 0.67 8.4 14.4 0.75 8.2 14.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ALMT PF11744.8 OAJ28699.1 - 0.74 8.6 6.6 0.75 8.6 6.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 OAJ28699.1 - 0.78 8.4 9.4 0.83 8.3 9.4 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 OAJ28699.1 - 0.83 8.1 8.0 0.96 7.9 8.0 1.0 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 OAJ28699.1 - 1.1 7.5 19.2 1.1 7.4 19.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4199 PF13858.6 OAJ28699.1 - 1.1 9.7 2.5 1.3 9.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) P16-Arc PF04699.14 OAJ28699.1 - 1.1 9.8 8.2 1.5 9.3 8.2 1.2 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF3408 PF11888.8 OAJ28699.1 - 1.4 9.1 11.4 2 8.6 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) UPF0524 PF15823.5 OAJ28699.1 - 2.2 7.6 9.6 3.1 7.1 9.6 1.2 1 0 0 1 1 1 0 UPF0524 of C3orf70 Herpes_DNAp_acc PF04929.12 OAJ28699.1 - 2.4 7.1 13.9 2.9 6.8 13.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CLN3 PF02487.17 OAJ28699.1 - 2.8 6.9 5.4 3.1 6.7 5.4 1.1 1 0 0 1 1 1 0 CLN3 protein Ndc1_Nup PF09531.10 OAJ28699.1 - 3 6.4 14.3 3.3 6.3 14.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CobT PF06213.12 OAJ28699.1 - 3.6 6.9 13.7 4.3 6.7 13.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EIF4E-T PF10477.9 OAJ28699.1 - 3.8 6.2 19.2 4.2 6.1 19.2 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RNA_pol_Rbc25 PF08292.12 OAJ28699.1 - 4.8 7.4 10.1 6.8 6.9 10.1 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 FHIPEP PF00771.20 OAJ28699.1 - 5.5 5.3 5.7 6.7 5.0 5.7 1.1 1 0 0 1 1 1 0 FHIPEP family Radical_SAM_N PF08497.10 OAJ28699.1 - 8 5.6 7.6 11 5.2 7.6 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal DUF4834 PF16118.5 OAJ28699.1 - 8.3 7.5 14.2 13 6.9 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 OAJ28699.1 - 9 6.7 8.3 14 6.1 8.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SHS2_Rpb7-N PF03876.17 OAJ28701.1 - 4.9e-14 52.4 0.0 8.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ28701.1 - 1.1e-13 51.3 0.1 1.6e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 OAJ28701.1 - 0.03 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF3682 PF12446.8 OAJ28702.1 - 0.0014 19.1 5.8 0.0014 19.1 5.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3682) RVT_1 PF00078.27 OAJ28703.1 - 1.4e-26 93.4 0.0 2.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ28703.1 - 6.5e-17 61.5 0.1 2e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ28703.1 - 1.3e-10 41.6 0.0 4e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 OAJ28703.1 - 1.9e-09 37.4 2.0 6.5e-09 35.6 2.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 OAJ28703.1 - 0.00095 19.8 0.4 0.0031 18.2 0.4 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_3 PF13456.6 OAJ28703.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like DUF4110 PF13422.6 OAJ28703.1 - 0.73 9.9 6.4 0.086 12.9 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) G-patch PF01585.23 OAJ28705.1 - 0.00068 19.5 0.3 0.0032 17.3 0.3 2.2 2 0 0 2 2 2 1 G-patch domain EBV-NA3 PF05009.12 OAJ28705.1 - 0.26 10.8 4.1 8.3 5.9 1.7 2.4 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.12 OAJ28705.1 - 6.1 6.1 7.0 18 4.5 7.0 1.7 1 0 0 1 1 1 0 NOA36 protein DSPc PF00782.20 OAJ28706.1 - 2.9e-27 95.1 0.0 7.5e-21 74.3 0.0 2.9 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ28706.1 - 0.0026 17.4 0.0 0.0072 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Exo_endo_phos_2 PF14529.6 OAJ28708.1 - 4e-12 46.0 0.0 9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 OAJ28708.1 - 4.1e-09 36.3 0.0 5.4e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 OAJ28708.1 - 1.2e-05 25.0 0.7 3.7e-05 23.4 0.7 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRP7 PF12923.7 OAJ28708.1 - 0.15 12.2 0.2 0.34 11.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SUIM_assoc PF16619.5 OAJ28708.1 - 1.8 8.7 5.6 1.2 9.2 1.8 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GARS_N PF02844.15 OAJ28709.1 - 9.9e-34 116.0 0.2 1.3e-33 115.6 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain p450 PF00067.22 OAJ28710.1 - 3.3e-63 214.0 0.0 4.4e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PLA2_B PF01735.18 OAJ28712.1 - 5e-12 45.0 0.0 3.1e-06 25.9 1.5 2.6 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Med3 PF11593.8 OAJ28712.1 - 8.8 5.4 11.3 12 4.9 11.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SUZ PF12752.7 OAJ28713.1 - 1.1e-10 42.1 1.8 1.1e-10 42.1 1.8 3.1 3 1 0 3 3 3 1 SUZ domain TEX19 PF15553.6 OAJ28713.1 - 3 7.8 4.4 3.1 7.8 2.8 1.8 1 1 0 2 2 2 0 Testis-expressed protein 19 Metallophos_2 PF12850.7 OAJ28714.1 - 9.7e-18 64.9 0.1 1.6e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 OAJ28714.1 - 0.00094 19.7 0.8 0.13 12.7 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase BUD22 PF09073.10 OAJ28714.1 - 2.8 7.2 22.6 3.7 6.8 22.6 1.0 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 OAJ28714.1 - 5.7 7.2 15.2 8.4 6.6 15.2 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR TFIIF_alpha PF05793.12 OAJ28714.1 - 6.1 5.3 18.0 8.2 4.9 18.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HhH-GPD PF00730.25 OAJ28716.1 - 1.4e-11 44.8 0.0 3.9e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ28716.1 - 0.079 12.9 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 OAJ28716.1 - 0.17 12.0 0.0 0.62 10.2 0.0 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif FHA PF00498.26 OAJ28717.1 - 0.013 15.9 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 FHA domain FHA PF00498.26 OAJ28718.1 - 0.0015 18.8 0.0 0.005 17.1 0.0 1.8 2 0 0 2 2 2 1 FHA domain CDC48_2 PF02933.17 OAJ28719.1 - 0.02 14.7 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF2543 PF10820.8 OAJ28722.1 - 0.092 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) tRNA-synt_His PF13393.6 OAJ28722.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase LPD5 PF18799.1 OAJ28723.1 - 0.035 14.5 1.6 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Exo_endo_phos PF03372.23 OAJ28724.1 - 2.4e-13 50.2 0.1 5.9e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 OAJ28724.1 - 4.3e-06 26.7 2.3 2.9e-05 24.1 2.3 2.3 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 OAJ28724.1 - 8e-05 22.5 0.0 0.0033 17.2 0.0 2.4 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3808 PF10300.9 OAJ28725.1 - 8.1e-77 259.0 0.0 1.3e-76 258.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) CRAL_TRIO PF00650.20 OAJ28725.1 - 5.6e-31 107.4 0.0 1.1e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ28725.1 - 9.9e-13 48.1 0.6 2.9e-12 46.6 0.6 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ28725.1 - 4.5e-10 39.8 0.0 1.2e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPR_8 PF13181.6 OAJ28725.1 - 0.13 12.5 2.1 0.48 10.8 0.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ28725.1 - 0.2 11.8 10.9 24 5.3 1.7 5.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28725.1 - 0.88 9.5 7.3 1.2 9.1 1.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3322 PF11795.8 OAJ28725.1 - 0.92 9.5 4.1 0.37 10.8 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) TPR_7 PF13176.6 OAJ28725.1 - 3.9 7.7 6.9 8.5 6.7 0.7 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28725.1 - 4.1 7.8 6.1 4.3 7.7 2.3 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF383 PF04063.14 OAJ28726.1 - 1.1e-49 168.7 0.0 8.5e-49 165.8 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 OAJ28726.1 - 9e-18 63.9 2.8 1.9e-17 62.9 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF384) DUF883 PF05957.13 OAJ28726.1 - 0.087 13.4 0.5 0.087 13.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4805 PF16063.5 OAJ28726.1 - 0.19 11.0 2.5 0.32 10.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) AAA_18 PF13238.6 OAJ28727.1 - 2.2e-25 89.7 0.0 1.1e-24 87.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ28727.1 - 0.0078 16.5 0.1 0.022 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ28727.1 - 0.011 16.2 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 OAJ28727.1 - 0.012 15.7 0.7 1.6 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 OAJ28727.1 - 0.017 15.5 0.0 3.4 8.1 0.0 2.8 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 OAJ28727.1 - 0.033 13.6 0.0 0.081 12.4 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_22 PF13401.6 OAJ28727.1 - 0.033 14.5 0.0 0.076 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAJ28727.1 - 0.038 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 OAJ28727.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 OAJ28727.1 - 0.083 12.2 0.3 0.2 11.0 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ADK PF00406.22 OAJ28727.1 - 0.11 12.6 0.1 9.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.6 OAJ28727.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain Sdh_cyt PF01127.22 OAJ28728.1 - 2.9e-23 82.2 4.9 3.9e-23 81.8 4.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pam16 PF03656.13 OAJ28728.1 - 0.099 12.7 0.3 0.14 12.2 0.3 1.2 1 0 0 1 1 1 0 Pam16 His_Phos_1 PF00300.22 OAJ28729.1 - 5e-18 65.5 0.0 7.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SVIP PF15811.5 OAJ28729.1 - 0.11 12.9 4.4 0.28 11.7 4.4 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Pkinase PF00069.25 OAJ28730.1 - 4.1e-54 183.7 0.0 1e-33 116.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28730.1 - 8.2e-23 81.0 0.1 2.5e-15 56.5 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 OAJ28730.1 - 0.0021 18.0 2.5 0.028 14.4 0.4 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ28730.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 OAJ28730.1 - 0.058 14.1 0.0 0.19 12.5 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain Kinase-like PF14531.6 OAJ28730.1 - 0.085 12.2 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.6 OAJ28731.1 - 3.3e-60 204.1 38.7 4e-60 203.8 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ28731.1 - 8.1e-27 93.9 33.9 1.1e-26 93.5 33.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3246 PF11596.8 OAJ28731.1 - 6.4 6.1 7.7 3.9 6.8 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Semialdhyde_dhC PF02774.18 OAJ28733.1 - 2e-42 145.3 0.1 3.5e-42 144.6 0.0 1.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 OAJ28733.1 - 1.5e-27 96.4 0.0 3.3e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 OAJ28733.1 - 0.0012 18.9 0.0 0.003 17.7 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 OAJ28733.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 OAJ28733.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F-box-like PF12937.7 OAJ28734.1 - 0.087 12.7 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 F-box-like SNARE PF05739.19 OAJ28735.1 - 6e-11 42.2 0.3 6e-11 42.2 0.3 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 OAJ28735.1 - 1.3e-10 41.5 4.1 2.7e-10 40.5 1.6 2.3 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 OAJ28735.1 - 0.00073 19.3 9.9 0.0021 17.8 1.5 2.3 2 0 0 2 2 2 2 Syntaxin Caskin1-CID PF16600.5 OAJ28735.1 - 0.02 15.5 1.2 0.06 13.9 1.2 1.8 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DUF5345 PF17280.2 OAJ28735.1 - 0.26 11.3 1.9 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DnaJ PF00226.31 OAJ28736.1 - 1e-16 60.8 0.1 2.7e-16 59.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain RAC_head PF16717.5 OAJ28736.1 - 3.4e-13 50.4 4.8 3.4e-13 50.4 4.8 3.2 3 0 0 3 3 3 1 Ribosome-associated complex head domain AAA_23 PF13476.6 OAJ28736.1 - 0.34 11.4 9.1 0.65 10.5 9.1 1.5 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 OAJ28736.1 - 2.8 6.6 6.4 4.2 6.0 6.4 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 OAJ28736.1 - 3.8 5.5 6.2 5 5.1 6.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prothymosin PF03247.14 OAJ28737.1 - 2.1 8.8 21.6 0.056 13.9 10.8 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family ELFV_dehydrog PF00208.21 OAJ28738.1 - 7.7e-49 166.6 0.2 8.8e-49 166.4 0.2 1.0 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2255 PF10012.9 OAJ28738.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) WGG PF10273.9 OAJ28739.1 - 1.4e-21 76.9 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 PPP4R2 PF09184.11 OAJ28739.1 - 0.0064 16.1 6.7 0.0086 15.7 6.7 1.2 1 0 0 1 1 1 1 PPP4R2 RRP7 PF12923.7 OAJ28739.1 - 0.0096 16.1 0.6 0.021 14.9 0.6 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CDC45 PF02724.14 OAJ28739.1 - 0.055 11.8 9.9 0.068 11.5 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 OAJ28739.1 - 0.73 8.9 15.7 1.2 8.2 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PTPRCAP PF15713.5 OAJ28739.1 - 0.99 9.7 11.8 0.053 13.8 6.1 1.7 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 OAJ28739.1 - 3.3 5.8 11.6 3.4 5.7 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 OAJ28739.1 - 7.5 6.6 8.6 13 5.8 8.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SKN1 PF03935.15 OAJ28740.1 - 3.7e-82 276.3 0.2 4.6e-82 276.0 0.2 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ28741.1 - 7.1e-20 70.9 0.0 7.6e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Aconitase PF00330.20 OAJ28742.1 - 1.6e-150 502.1 0.0 2.6e-150 501.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ28742.1 - 3.1e-43 147.2 0.0 5.5e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SKN1 PF03935.15 OAJ28743.1 - 4.9e-146 487.1 9.1 1.2e-102 344.0 7.5 2.2 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ28744.1 - 7.7e-07 27.9 0.0 1e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) HTH_Tnp_Tc3_2 PF01498.18 OAJ28747.1 - 9.4e-17 61.0 7.3 9.4e-17 61.0 7.3 2.0 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 OAJ28747.1 - 1.1e-12 47.9 0.0 2.5e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ28747.1 - 0.00026 21.5 2.7 0.00026 21.5 2.7 3.2 3 1 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 OAJ28747.1 - 0.00098 19.1 2.4 0.006 16.6 0.3 2.5 2 0 0 2 2 2 1 Winged helix-turn helix HTH_21 PF13276.6 OAJ28747.1 - 0.0013 18.8 3.3 0.0018 18.4 1.7 2.1 2 0 0 2 2 2 1 HTH-like domain HTH_23 PF13384.6 OAJ28747.1 - 0.018 14.8 0.8 0.86 9.5 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ28747.1 - 0.02 13.9 0.3 0.65 8.9 0.1 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain DHDPS PF00701.22 OAJ28747.1 - 0.057 12.1 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family DUF668 PF05003.12 OAJ28747.1 - 0.064 13.7 1.0 0.2 12.1 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF668) HLH PF00010.26 OAJ28748.1 - 3.1e-07 30.2 0.3 9.5e-07 28.7 0.3 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Angiomotin_C PF12240.8 OAJ28748.1 - 0.00091 18.8 1.2 0.00091 18.8 1.2 3.1 3 0 0 3 3 3 1 Angiomotin C terminal Spt20 PF12090.8 OAJ28748.1 - 0.45 10.1 42.1 0.24 11.0 20.3 2.6 2 0 0 2 2 2 0 Spt20 family EIIBC-GUT_N PF03612.14 OAJ28748.1 - 2.7 7.7 6.4 1.9 8.2 1.4 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus EPL1 PF10513.9 OAJ28748.1 - 4.6 7.6 17.2 3.4 8.0 4.7 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like Citrate_synt PF00285.21 OAJ28750.1 - 1.2e-91 307.5 0.0 1.5e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain HTH_57 PF18679.1 OAJ28751.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 ThcOx helix turn helix domain Voltage_CLC PF00654.20 OAJ28752.1 - 2.5e-89 300.0 29.2 2.5e-89 300.0 29.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel GP11 PF08677.10 OAJ28752.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 GP11 baseplate wedge protein NDC10_II PF16787.5 OAJ28756.1 - 6.9e-34 117.3 0.0 8.8e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Cutinase PF01083.22 OAJ28757.1 - 8.2e-23 81.3 0.2 9.8e-23 81.0 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ28757.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Pro_dh PF01619.18 OAJ28759.1 - 2.7e-51 174.9 0.0 7.6e-32 111.0 0.0 3.1 1 1 1 2 2 2 2 Proline dehydrogenase DPBB_1 PF03330.18 OAJ28760.1 - 9.7e-08 32.2 0.2 1.9e-07 31.2 0.1 1.5 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 OAJ28760.1 - 0.0017 18.2 0.9 0.0029 17.4 0.9 1.6 1 1 0 1 1 1 1 Barwin family PPR_2 PF13041.6 OAJ28761.1 - 2.6e-16 59.5 0.3 0.00045 20.4 0.0 4.9 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 OAJ28761.1 - 3.2e-11 43.1 0.0 9.5e-06 25.6 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 OAJ28761.1 - 1.1e-06 28.5 2.4 0.45 10.9 0.1 5.3 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 OAJ28761.1 - 8.3e-06 25.3 0.1 1.2 8.5 0.0 3.8 4 0 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAJ28761.1 - 7.5e-05 22.3 0.1 1.3 8.8 0.0 4.3 4 0 0 4 4 4 2 PPR repeat ATP13 PF12921.7 OAJ28761.1 - 0.00053 19.8 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ATPase expression DUF2431 PF10354.9 OAJ28763.1 - 3.1e-41 141.5 0.0 4.7e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.6 OAJ28763.1 - 0.075 13.4 0.3 0.075 13.4 0.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 OAJ28763.1 - 0.17 11.9 2.1 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal Band_3_cyto PF07565.13 OAJ28763.1 - 0.33 10.7 1.0 0.47 10.2 1.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RVT_1 PF00078.27 OAJ28764.1 - 4.6e-23 81.9 0.0 7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ28764.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ28764.1 - 0.34 10.4 4.2 1.1 8.7 4.2 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 OAJ28765.1 - 2.6e-15 57.2 0.0 7.1e-14 52.5 0.0 2.4 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 OAJ28765.1 - 3.4e-05 24.4 2.3 3.4e-05 24.4 2.3 1.7 2 0 0 2 2 2 1 Pre-SET motif PPR_2 PF13041.6 OAJ28766.1 - 1.1e-08 35.1 0.0 7.8e-08 32.4 0.0 2.5 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 OAJ28766.1 - 0.01 15.9 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DUF5560 PF17715.1 OAJ28766.1 - 0.017 14.6 2.1 0.18 11.2 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5560) DUF778 PF05608.12 OAJ28766.1 - 0.66 10.3 3.9 0.4 11.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF778) Dus PF01207.17 OAJ28767.1 - 3e-48 164.5 0.0 9.2e-33 113.6 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 OAJ28767.1 - 1.7e-07 31.0 5.5 0.0024 17.7 0.5 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ28767.1 - 6.9e-07 29.1 13.5 0.0015 18.5 4.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 OAJ28767.1 - 2.4e-06 27.2 11.6 0.00012 21.8 2.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 OAJ28767.1 - 5.3e-06 27.1 1.0 0.00079 20.1 0.4 2.6 2 0 0 2 2 2 1 Torus domain Lustrin_cystein PF14625.6 OAJ28767.1 - 0.078 13.4 1.7 6.9 7.1 0.3 2.6 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Apolipoprotein PF01442.18 OAJ28768.1 - 0.0011 18.9 10.2 0.0022 17.9 10.2 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ28768.1 - 0.011 15.8 3.8 0.68 10.0 0.4 2.6 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.20 OAJ28768.1 - 0.017 15.0 2.8 0.02 14.8 1.1 1.9 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.6 OAJ28768.1 - 0.02 14.3 7.0 0.054 12.8 7.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Muted PF14942.6 OAJ28768.1 - 0.023 15.1 2.2 0.023 15.1 2.2 1.5 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein GIDA_assoc PF13932.6 OAJ28768.1 - 0.023 14.9 1.6 0.038 14.2 1.6 1.3 1 0 0 1 1 1 0 GidA associated domain Exonuc_VII_L PF02601.15 OAJ28768.1 - 0.029 13.9 5.2 0.045 13.3 5.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 OAJ28768.1 - 0.032 15.0 1.8 0.064 14.0 1.3 1.8 1 1 1 2 2 2 0 Occludin homology domain Cep57_MT_bd PF06657.13 OAJ28768.1 - 0.038 14.4 5.5 0.082 13.4 4.6 2.1 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 OAJ28768.1 - 0.042 14.2 9.5 0.094 13.0 9.5 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CHAD PF05235.14 OAJ28768.1 - 0.046 13.7 8.2 0.069 13.1 7.9 1.4 1 1 0 1 1 1 0 CHAD domain Cob_adeno_trans PF01923.18 OAJ28768.1 - 0.048 13.8 4.3 1.6 8.8 1.0 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prominin PF05478.11 OAJ28768.1 - 0.053 11.5 0.7 0.075 11.0 0.7 1.3 1 0 0 1 1 1 0 Prominin ApoLp-III PF07464.11 OAJ28768.1 - 0.07 13.2 4.6 0.1 12.7 1.9 2.4 2 1 1 3 3 2 0 Apolipophorin-III precursor (apoLp-III) DUF842 PF05811.13 OAJ28768.1 - 0.088 12.5 8.5 0.052 13.3 5.7 2.0 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) CENP-F_leu_zip PF10473.9 OAJ28768.1 - 0.12 12.4 5.7 0.31 11.1 5.7 1.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 OAJ28768.1 - 0.13 12.6 9.5 0.59 10.5 6.0 3.1 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 OAJ28768.1 - 0.14 12.4 6.6 1.1 9.6 0.0 2.4 1 1 2 3 3 3 0 Tup N-terminal DUF1640 PF07798.11 OAJ28768.1 - 0.15 12.1 7.4 0.3 11.1 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) IZUMO PF15005.6 OAJ28768.1 - 0.15 12.5 1.9 0.39 11.2 0.7 1.9 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF1664 PF07889.12 OAJ28768.1 - 0.32 11.0 5.8 0.93 9.5 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) RYDR_ITPR PF01365.21 OAJ28768.1 - 0.33 10.3 5.2 0.54 9.6 5.2 1.3 1 0 0 1 1 1 0 RIH domain KxDL PF10241.9 OAJ28768.1 - 0.64 10.3 8.8 2.9 8.3 5.8 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 OAJ28768.1 - 0.87 10.2 12.9 0.91 10.2 9.4 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spectrin PF00435.21 OAJ28768.1 - 0.89 10.1 7.7 11 6.6 7.7 2.2 1 1 0 1 1 1 0 Spectrin repeat DUF4456 PF14644.6 OAJ28768.1 - 0.94 9.1 11.3 8.2 6.0 10.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4456) Phage_GPO PF05929.11 OAJ28768.1 - 1.2 8.7 6.3 1.5 8.4 5.8 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fzo_mitofusin PF04799.13 OAJ28768.1 - 2.2 7.8 9.3 14 5.2 1.9 2.5 1 1 1 2 2 2 0 fzo-like conserved region DUF883 PF05957.13 OAJ28768.1 - 3.4 8.3 9.2 32 5.2 3.9 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_cc PF11790.8 OAJ28769.1 - 2.1e-51 174.8 2.1 2.8e-51 174.4 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Med15 PF09606.10 OAJ28770.1 - 0.68 8.5 147.7 0.018 13.8 73.6 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DEAD PF00270.29 OAJ28771.1 - 3.2e-18 66.1 0.1 8.8e-18 64.7 0.0 1.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ28771.1 - 0.021 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain LIP PF03583.14 OAJ28772.1 - 8.4e-39 133.6 0.2 6.6e-37 127.4 0.2 2.1 1 1 0 1 1 1 1 Secretory lipase NAD_binding_8 PF13450.6 OAJ28774.1 - 1.2e-08 35.0 0.0 3.9e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ28774.1 - 0.006 15.9 0.0 0.083 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ28774.1 - 0.025 13.6 0.7 0.064 12.3 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 OAJ28774.1 - 0.031 14.8 0.1 16 6.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ28774.1 - 0.036 13.7 0.6 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ28774.1 - 0.23 10.1 0.1 0.72 8.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Mito_carr PF00153.27 OAJ28775.1 - 1.3e-61 204.5 3.9 3.4e-21 74.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PDCD2_C PF04194.13 OAJ28776.1 - 8e-28 97.7 12.2 8e-28 97.7 12.2 3.3 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain RXT2_N PF08595.11 OAJ28776.1 - 1 9.4 15.3 2.4 8.2 3.4 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal BSP_II PF05432.11 OAJ28776.1 - 2.8 7.6 15.6 0.037 13.7 4.3 2.6 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 OAJ28776.1 - 7.4 5.8 27.3 5.1 6.3 11.9 2.3 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ28776.1 - 7.6 6.2 33.3 0.43 10.3 10.6 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Glutaredoxin PF00462.24 OAJ28777.1 - 8e-18 64.4 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin F-box-like PF12937.7 OAJ28778.1 - 1e-05 25.3 0.1 2.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ28778.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ28778.1 - 0.052 13.4 0.2 0.092 12.6 0.2 1.3 1 0 0 1 1 1 0 F-box E3_binding PF02817.17 OAJ28778.1 - 0.081 13.3 0.2 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 e3 binding domain Hamartin PF04388.12 OAJ28780.1 - 0.0037 16.0 0.0 0.0037 16.0 0.0 3.6 3 1 0 3 3 3 2 Hamartin protein Aminotran_4 PF01063.19 OAJ28780.1 - 0.005 16.7 0.0 0.052 13.4 0.0 2.6 1 1 0 1 1 1 1 Amino-transferase class IV DUF1843 PF08898.10 OAJ28780.1 - 1.1 9.8 7.4 3.2 8.3 0.2 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Phlebovirus_NSM PF07246.11 OAJ28780.1 - 2.2 7.6 6.7 1.1 8.5 3.6 2.0 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M EF-hand_6 PF13405.6 OAJ28781.1 - 6.3e-10 38.2 2.1 8.3e-05 22.2 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ28781.1 - 5.1e-08 31.9 5.7 0.00047 19.5 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 OAJ28781.1 - 2.1e-07 31.3 5.1 2.7e-06 27.7 1.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ28781.1 - 0.0044 16.5 2.5 0.09 12.3 0.4 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAJ28781.1 - 0.13 12.2 2.7 7.7 6.5 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain pair PRTP PF01366.18 OAJ28781.1 - 0.16 9.9 0.0 0.17 9.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Cellulase PF00150.18 OAJ28782.1 - 0.00048 19.6 0.0 0.00067 19.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_2 PF00152.20 OAJ28783.1 - 2.3e-85 286.5 0.2 3.5e-85 285.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ28783.1 - 7.1e-11 41.9 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF677 PF05055.12 OAJ28783.1 - 0.085 11.7 0.8 0.12 11.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) tRNA_anti_2 PF13742.6 OAJ28783.1 - 0.13 12.5 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Nucleos_tra2_C PF07662.13 OAJ28784.1 - 2.1e-69 233.5 0.5 4.4e-69 232.5 0.5 1.6 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 OAJ28784.1 - 2.5e-16 60.0 6.9 2.5e-16 60.0 6.9 3.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 OAJ28784.1 - 1.2 9.4 14.2 4.1 7.7 7.6 3.4 2 1 0 2 2 2 0 Nucleoside recognition DHHC PF01529.20 OAJ28785.1 - 1.1e-30 106.5 0.0 3.7e-30 104.7 0.0 1.7 1 1 0 1 1 1 1 DHHC palmitoyltransferase UDPGT PF00201.18 OAJ28786.1 - 4.1e-08 32.5 0.0 1.2e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_4_2 PF13477.6 OAJ28786.1 - 0.046 13.8 0.0 3.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Glycosyl transferase 4-like Ribosomal_S21 PF01165.20 OAJ28787.1 - 1.4e-10 40.7 5.1 2.7e-10 39.8 5.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 adh_short_C2 PF13561.6 OAJ28788.1 - 2.7e-47 161.3 0.9 3.7e-47 160.8 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ28788.1 - 5.6e-35 120.6 0.0 7.3e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ28788.1 - 5e-09 36.3 0.1 8.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Put_Phosphatase PF06888.12 OAJ28789.1 - 3.3e-50 170.7 0.0 4e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 OAJ28789.1 - 6.3e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LRR_6 PF13516.6 OAJ28790.1 - 0.00021 21.1 2.9 1.6 9.0 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_4 PF12799.7 OAJ28790.1 - 0.00028 21.2 2.3 1.5 9.4 0.0 5.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ28790.1 - 0.71 10.7 2.4 64 4.7 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat PPP4R2 PF09184.11 OAJ28790.1 - 0.78 9.3 5.8 1.6 8.3 5.8 1.4 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 OAJ28790.1 - 3.3 5.7 8.7 41 2.1 8.9 2.0 2 0 0 2 2 2 0 DNA polymerase phi DUF3245 PF11595.8 OAJ28790.1 - 5.2 7.5 13.3 25 5.3 13.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) 3Beta_HSD PF01073.19 OAJ28791.1 - 1.8e-15 56.7 0.0 1.3e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ28791.1 - 8.4e-13 48.3 1.2 3.4e-12 46.4 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ28791.1 - 1.1e-10 41.8 0.0 1.6e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAJ28791.1 - 9.3e-08 31.9 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 OAJ28791.1 - 1.4e-07 30.9 0.0 5.3e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ28791.1 - 2.3e-07 30.5 0.5 5.3e-07 29.4 0.0 1.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 OAJ28791.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAJ28791.1 - 0.0034 16.9 0.6 0.0086 15.5 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_2 PF03446.15 OAJ28791.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 OAJ28791.1 - 0.013 15.5 0.3 0.23 11.4 0.3 2.3 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 OAJ28791.1 - 0.041 14.1 0.1 0.26 11.5 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF5131 PF07505.11 OAJ28791.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) Complex1_LYR_2 PF13233.6 OAJ28792.1 - 1.4e-14 54.6 0.0 6.6e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Complex1_LYR-like UFD1 PF03152.14 OAJ28793.1 - 1.6e-66 223.1 0.0 2e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 OAJ28793.1 - 0.2 11.8 0.0 4.4 7.5 0.0 2.5 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain TFIIA PF03153.13 OAJ28794.1 - 0.00046 20.3 10.8 0.00046 20.3 10.8 2.4 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit TRAM_LAG1_CLN8 PF03798.16 OAJ28794.1 - 0.00097 18.9 10.4 0.00097 18.9 10.4 1.5 2 0 0 2 2 2 1 TLC domain zf-LYAR PF08790.11 OAJ28796.1 - 1.2e-11 44.3 1.1 1.2e-11 44.3 1.1 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 OAJ28796.1 - 0.18 11.5 1.7 0.63 9.7 1.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain eIF3_subunit PF08597.10 OAJ28797.1 - 9.2e-46 156.7 25.0 1e-45 156.5 25.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 OAJ28797.1 - 0.02 15.2 11.0 0.02 15.2 11.0 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAJ28797.1 - 0.38 9.0 11.3 0.44 8.8 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ28797.1 - 2.5 6.1 19.0 4 5.4 19.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 OAJ28797.1 - 7.5 6.3 24.8 1.7 8.4 8.9 2.9 2 1 1 3 3 3 0 Pox virus Ag35 surface protein zf-LYAR PF08790.11 OAJ28798.1 - 1.2e-11 44.3 1.1 1.2e-11 44.3 1.1 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_C2H2_ZHX PF18387.1 OAJ28798.1 - 0.18 11.5 1.7 0.63 9.7 1.4 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Ion_trans PF00520.31 OAJ28799.1 - 0.1 11.8 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 Ion transport protein DUF3541 PF12060.8 OAJ28799.1 - 0.13 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Peptidase_S8 PF00082.22 OAJ28800.1 - 5.7e-32 111.2 0.8 8.6e-32 110.6 0.8 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ28800.1 - 1.4e-09 38.6 0.0 2.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain tRNA-synt_2b PF00587.25 OAJ28801.1 - 5.7e-32 111.1 0.0 4.3e-29 101.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ28801.1 - 1.1e-16 60.7 0.2 2.5e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 OAJ28801.1 - 2.4e-13 49.9 0.0 5.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 OAJ28801.1 - 8.1e-11 41.8 0.0 1.8e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF502 PF04367.13 OAJ28801.1 - 0.041 13.8 0.0 0.5 10.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF502) SICA_alpha PF12887.7 OAJ28801.1 - 0.17 11.7 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 SICA extracellular alpha domain eIF3_subunit PF08597.10 OAJ28802.1 - 9.2e-46 156.7 25.0 1e-45 156.5 25.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 OAJ28802.1 - 0.02 15.2 11.0 0.02 15.2 11.0 3.4 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 OAJ28802.1 - 0.38 9.0 11.3 0.44 8.8 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ28802.1 - 2.5 6.1 19.0 4 5.4 19.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 OAJ28802.1 - 7.5 6.3 24.8 1.7 8.4 8.9 2.9 2 1 1 3 3 3 0 Pox virus Ag35 surface protein NAD_binding_10 PF13460.6 OAJ28803.1 - 3.9e-12 46.4 0.0 7.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 OAJ28803.1 - 3.8e-11 42.9 0.0 1e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 OAJ28803.1 - 4.5e-11 42.8 0.0 5.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 OAJ28803.1 - 1.4e-10 40.7 0.0 6.3e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ28803.1 - 1.2e-07 31.2 0.0 7.8e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 OAJ28803.1 - 9.3e-07 28.3 0.1 0.03 13.5 0.1 2.6 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ28803.1 - 4.7e-05 22.9 0.0 7.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 OAJ28803.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ28803.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ28803.1 - 0.0079 16.1 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAJ28803.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Nt_Gln_amidase PF09764.9 OAJ28804.1 - 3.2e-34 118.1 0.0 9.2e-33 113.4 0.0 2.9 1 1 0 1 1 1 1 N-terminal glutamine amidase PrmA PF06325.13 OAJ28805.1 - 8.5e-10 38.5 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 OAJ28805.1 - 1.2e-06 29.1 0.0 2.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ28805.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ28805.1 - 0.00015 22.4 0.0 0.00038 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ28805.1 - 0.00038 20.3 0.0 0.0007 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ28805.1 - 0.0043 16.6 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 OAJ28805.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 OAJ28805.1 - 0.042 14.6 0.4 0.1 13.4 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 OAJ28805.1 - 0.054 12.4 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 OAJ28805.1 - 0.069 14.2 0.0 0.2 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FAM176 PF14851.6 OAJ28805.1 - 1.5 8.5 3.8 3.3 7.3 2.7 2.1 2 0 0 2 2 2 0 FAM176 family DUF2457 PF10446.9 OAJ28805.1 - 3.8 6.5 11.6 8.2 5.4 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Arginase PF00491.21 OAJ28806.1 - 2e-73 247.3 0.0 2.4e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family COX6B PF02297.17 OAJ28807.1 - 6.6e-23 80.7 0.2 8.3e-23 80.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAJ28807.1 - 0.3 11.4 2.5 12 6.3 0.4 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Glyco_hydro_9 PF00759.19 OAJ28808.1 - 1.4e-46 159.7 4.5 1.1e-34 120.6 0.8 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 9 PP2C PF00481.21 OAJ28808.1 - 9.3e-10 38.6 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C GspL_C PF12693.7 OAJ28808.1 - 0.16 11.8 2.3 0.41 10.5 2.3 1.7 1 0 0 1 1 1 0 GspL periplasmic domain Aconitase PF00330.20 OAJ28809.1 - 1.4e-160 535.3 0.0 1.7e-160 535.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ28809.1 - 8.3e-42 142.6 0.0 1.6e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RNase_H PF00075.24 OAJ28810.1 - 5.1e-13 49.4 0.5 1.1e-12 48.3 0.1 1.8 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.6 OAJ28810.1 - 0.00087 20.0 0.2 0.002 18.8 0.2 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase CopK PF11525.8 OAJ28810.1 - 0.2 11.3 0.0 0.57 9.8 0.0 1.7 1 0 0 1 1 1 0 Copper resistance protein K RVT_1 PF00078.27 OAJ28811.1 - 1.8e-26 93.0 0.0 2.8e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ28811.1 - 6e-19 68.0 0.0 1.4e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ28811.1 - 4.5e-07 29.6 0.4 1.9e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SKA1 PF07160.12 OAJ28813.1 - 0.023 14.6 0.3 0.023 14.6 0.3 2.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF3829 PF12889.7 OAJ28813.1 - 0.025 14.0 1.5 2.1 7.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Syntaxin PF00804.25 OAJ28813.1 - 0.061 13.0 3.5 0.36 10.5 0.1 2.4 2 0 0 2 2 2 0 Syntaxin DEAD PF00270.29 OAJ28814.1 - 3.3e-38 131.2 0.0 1.2e-37 129.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ28814.1 - 2.6e-18 66.4 0.0 7.4e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ28814.1 - 3.2e-14 52.9 0.0 6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 OAJ28814.1 - 1.5e-06 28.3 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 OAJ28814.1 - 0.03 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) AAA_22 PF13401.6 OAJ28814.1 - 0.035 14.4 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain CSRNP_N PF16019.5 OAJ28814.1 - 0.41 10.5 6.8 0.74 9.7 6.8 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CCDC106 PF15794.5 OAJ28814.1 - 1 9.1 15.1 2 8.1 15.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MFMR_assoc PF16596.5 OAJ28814.1 - 2.2 8.7 8.4 0.62 10.5 4.6 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR Tombus_P33 PF08500.10 OAJ28814.1 - 7.6 6.5 7.3 17 5.4 6.7 1.8 1 1 0 1 1 1 0 Tombusvirus p33 RAP1 PF07218.11 OAJ28815.1 - 0.0031 15.9 13.9 0.0034 15.7 13.9 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 OAJ28815.1 - 1.6 7.5 16.2 1.7 7.4 16.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 OAJ28815.1 - 5.8 5.4 19.1 5.5 5.5 19.1 1.1 1 0 0 1 1 1 0 Hamartin protein CytochromB561_N PF09786.9 OAJ28815.1 - 9.8 5.0 20.8 12 4.8 20.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Antifungal_pept PF11410.8 OAJ28816.1 - 1.3 9.0 7.5 0.37 10.7 1.6 2.6 2 2 0 2 2 2 0 Antifungal peptide SSP160 PF06933.11 OAJ28816.1 - 5.9 5.0 17.2 6.4 4.8 17.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1688 PF07958.11 OAJ28817.1 - 5.1e-153 509.7 0.0 2e-151 504.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) KH_6 PF15985.5 OAJ28818.1 - 2.5e-09 37.3 0.0 4.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 OAJ28818.1 - 1e-06 28.5 2.9 7.3e-06 25.8 1.4 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain Tub_N PF16322.5 OAJ28818.1 - 1 9.7 3.1 0.4 11.0 0.5 1.6 2 0 0 2 2 2 0 Tubby N-terminal Mito_carr PF00153.27 OAJ28819.1 - 3.5e-60 199.9 3.8 3.9e-21 74.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Macoilin PF09726.9 OAJ28820.1 - 1.3 7.4 5.0 1.7 7.1 5.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 OAJ28820.1 - 3.5 6.3 6.6 4 6.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Actin PF00022.19 OAJ28821.1 - 2.5e-26 92.2 0.0 2e-16 59.6 0.0 3.8 3 1 0 3 3 3 2 Actin Sporozoite_P67 PF05642.11 OAJ28821.1 - 1.1 7.3 9.2 0.18 9.9 4.7 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nitroreductase PF00881.24 OAJ28822.1 - 5.1e-11 42.9 0.0 6.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family HK PF02110.15 OAJ28824.1 - 9.8e-58 195.4 9.5 2.8e-56 190.7 6.0 2.6 2 1 1 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 OAJ28824.1 - 8.8e-44 149.0 0.1 1.4e-42 145.1 0.1 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 OAJ28824.1 - 2.5e-07 30.4 0.8 4.2e-07 29.6 0.8 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Polysacc_deac_1 PF01522.21 OAJ28825.1 - 5.2e-23 81.3 0.0 9.5e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 OAJ28825.1 - 0.0033 16.9 0.0 0.007 15.9 0.0 1.7 1 0 0 1 1 1 1 Virulence protein nec1 Lipase_3 PF01764.25 OAJ28827.1 - 1.8e-12 47.3 0.0 4.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) NARP1 PF12569.8 OAJ28827.1 - 2.9 6.7 5.3 0.55 9.1 0.9 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 NOA36 PF06524.12 OAJ28827.1 - 9.4 5.5 8.9 23 4.2 8.9 1.6 1 0 0 1 1 1 0 NOA36 protein Pex24p PF06398.11 OAJ28828.1 - 9.2e-34 117.0 0.4 3.1e-27 95.5 0.0 2.5 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin RNA_pol_Rpb1_1 PF04997.12 OAJ28829.1 - 1.1e-87 294.2 0.1 1.7e-87 293.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 OAJ28829.1 - 3.4e-69 232.3 0.0 5.6e-69 231.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ28829.1 - 5.8e-38 130.3 0.0 1.1e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 OAJ28829.1 - 1.6e-27 95.5 0.0 3.7e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 OAJ28829.1 - 1.9e-26 93.1 0.0 3.5e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 SufE PF02657.15 OAJ28830.1 - 0.098 12.5 1.1 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 Fe-S metabolism associated domain HTH_Tnp_ISL3 PF13542.6 OAJ28830.1 - 0.38 10.2 2.5 1.3 8.5 2.5 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 EHN PF06441.12 OAJ28832.1 - 4.4e-20 72.1 0.2 8.9e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ28832.1 - 5.1e-12 46.0 0.1 1.1e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Gaa1 PF04114.14 OAJ28832.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component Mg_trans_NIPA PF05653.14 OAJ28833.1 - 2.1e-07 30.4 0.7 2.5e-07 30.1 0.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Cmc1 PF08583.10 OAJ28834.1 - 3.7e-17 62.1 1.3 5.4e-17 61.6 1.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DEAD PF00270.29 OAJ28835.1 - 7.8e-30 103.9 0.0 5.8e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ28835.1 - 1.2e-21 77.1 0.0 4.1e-21 75.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ28835.1 - 0.0099 15.9 0.0 0.064 13.3 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 OAJ28835.1 - 4.1 5.5 18.4 8.3 4.5 18.4 1.4 1 0 0 1 1 1 0 Nop14-like family DJ-1_PfpI PF01965.24 OAJ28836.1 - 5.8e-11 42.5 0.0 1.5e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 OAJ28836.1 - 6.4e-06 26.0 0.0 0.00011 22.0 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 OAJ28836.1 - 0.067 12.8 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain MFS_1 PF07690.16 OAJ28837.1 - 3.6e-23 82.0 28.7 6e-18 64.9 10.2 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ28837.1 - 5.3e-09 35.4 0.0 0.013 14.3 2.7 3.3 2 1 1 3 3 3 3 MFS_1 like family ATG22 PF11700.8 OAJ28837.1 - 0.03 13.0 14.1 0.011 14.4 1.8 2.5 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_3 PF05977.13 OAJ28837.1 - 0.14 10.5 0.0 0.14 10.5 0.0 2.9 3 0 0 3 3 3 0 Transmembrane secretion effector LRR_8 PF13855.6 OAJ28838.1 - 1.6e-13 50.2 15.4 5.1e-09 35.8 6.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 OAJ28838.1 - 3.8e-13 49.4 8.9 1.9e-05 24.9 2.7 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 OAJ28838.1 - 0.46 10.7 13.5 9.4 6.6 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 OAJ28838.1 - 0.61 10.9 12.7 24 6.0 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat Sec6 PF06046.13 OAJ28839.1 - 1.3e-146 489.3 0.0 2.1e-146 488.6 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 OAJ28839.1 - 0.00073 18.6 1.5 0.00073 18.6 1.5 2.5 3 0 0 3 3 3 1 Vps53-like, N-terminal Stanniocalcin PF03298.13 OAJ28839.1 - 0.061 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Stanniocalcin family Ribosomal_60s PF00428.19 OAJ28840.1 - 8.5e-27 93.6 10.0 1e-26 93.3 10.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 OAJ28841.1 - 8.6e-32 108.9 0.2 1.1e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 OAJ28841.1 - 0.045 13.8 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH TPR_2 PF07719.17 OAJ28842.1 - 3.1e-07 30.0 0.7 8.1e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28842.1 - 2.8e-06 26.9 0.9 0.00021 21.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ28842.1 - 0.017 15.3 0.2 0.076 13.3 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ28842.1 - 0.02 14.6 2.1 0.028 14.1 0.0 2.3 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 OAJ28842.1 - 0.02 15.0 0.0 0.02 15.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4523 PF15023.6 OAJ28842.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Med3 PF11593.8 OAJ28842.1 - 0.23 10.6 5.5 0.29 10.3 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_19 PF14559.6 OAJ28843.1 - 3.1e-06 27.6 1.0 0.029 14.9 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ28843.1 - 4.6e-05 24.0 6.2 0.12 13.1 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ28843.1 - 9.9e-05 22.2 0.0 0.012 15.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ28843.1 - 0.00062 20.2 0.6 0.022 15.4 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28843.1 - 0.0031 17.8 0.1 0.28 11.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ28843.1 - 0.0079 16.0 0.8 0.067 13.1 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ28843.1 - 0.0082 16.9 4.7 0.48 11.4 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 OAJ28843.1 - 0.023 15.3 0.1 2 9.3 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 OAJ28843.1 - 0.1 12.8 0.4 15 5.9 0.0 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_1 PF00515.28 OAJ28843.1 - 0.15 12.0 0.0 5.7 6.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Thioredoxin PF00085.20 OAJ28845.1 - 3.8e-23 81.4 0.0 2.3e-22 78.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ28845.1 - 6.9e-05 23.2 0.0 0.00029 21.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 OAJ28845.1 - 0.012 15.6 0.2 0.031 14.2 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family OST3_OST6 PF04756.13 OAJ28845.1 - 0.013 14.8 0.1 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ28845.1 - 0.019 15.3 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ28845.1 - 0.094 12.9 0.0 0.094 12.9 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like GHMP_kinases_N PF00288.26 OAJ28846.1 - 2e-10 40.7 0.3 6.3e-10 39.2 0.2 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ28846.1 - 0.0026 18.1 0.0 0.0087 16.4 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal RNA_pol_Rpb1_5 PF04998.17 OAJ28847.1 - 1.4e-15 57.4 0.0 1.8e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Apt1 PF10351.9 OAJ28847.1 - 1.9 7.2 6.3 2.5 6.9 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 OAJ28847.1 - 4.1 5.4 15.7 5.6 4.9 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 OAJ28847.1 - 8.6 4.8 20.3 10 4.6 20.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_integrase PF00589.22 OAJ28849.1 - 2.4e-05 24.2 0.0 5.4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Phage integrase family RCC1 PF00415.18 OAJ28850.1 - 1.2e-14 54.6 5.2 0.011 16.3 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 OAJ28850.1 - 1.5e-10 41.2 0.0 3.9e-05 23.8 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 OAJ28850.1 - 1.2e-08 35.1 0.3 2.2e-06 27.8 0.2 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ28850.1 - 2.3e-07 31.2 0.4 8.4e-05 23.1 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 OAJ28850.1 - 5.1e-06 26.1 14.5 0.0017 18.1 0.0 6.3 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 OAJ28850.1 - 5.6e-06 26.9 0.0 1.6e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ28850.1 - 5.9e-05 23.2 1.1 0.39 11.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAJ28850.1 - 0.0063 16.9 3.9 0.29 11.7 0.3 3.4 3 0 0 3 3 3 1 Ankyrin repeat AMP-binding PF00501.28 OAJ28851.1 - 3.4e-70 236.8 0.0 4.3e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ28851.1 - 0.00081 20.3 0.2 0.0023 18.9 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ig_Tie2_1 PF10430.9 OAJ28851.1 - 0.065 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 MFAP1 PF06991.11 OAJ28852.1 - 1.7e-63 214.4 20.8 1.7e-63 214.4 20.8 2.4 2 0 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 OAJ28852.1 - 0.12 12.5 1.0 0.29 11.3 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle THF_DHG_CYH PF00763.23 OAJ28853.1 - 1.1e-22 80.5 0.0 2.3e-22 79.4 0.0 1.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 OAJ28853.1 - 2e-13 50.0 0.1 6.1e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 OAJ28853.1 - 0.086 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF2420 PF10336.9 OAJ28854.1 - 4.6e-05 23.4 0.0 8.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) NAD_binding_11 PF14833.6 OAJ28855.1 - 1e-12 48.4 0.0 1.9e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pyridoxal_deC PF00282.19 OAJ28856.1 - 3.1e-41 141.3 0.0 3.7e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain RPN6_N PF18055.1 OAJ28860.1 - 4.8e-41 139.8 4.6 2.6e-40 137.4 2.2 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 OAJ28860.1 - 4.4e-20 72.2 0.1 1.5e-19 70.4 0.1 2.0 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 OAJ28860.1 - 8.8e-14 50.9 0.4 2.2e-13 49.7 0.4 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain Alkyl_sulf_dimr PF14863.6 OAJ28860.1 - 0.006 17.0 2.7 0.1 13.0 0.6 3.3 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation DUF627 PF04781.12 OAJ28860.1 - 0.013 15.5 1.4 2.3 8.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 OAJ28860.1 - 0.054 14.1 15.6 3 8.6 0.0 4.5 3 2 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ28860.1 - 0.065 13.5 2.0 3.7 7.8 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 OAJ28860.1 - 0.079 13.6 6.6 27 5.7 0.2 5.4 4 1 0 4 4 4 0 Tetratricopeptide repeat ICAT PF06384.11 OAJ28860.1 - 0.098 12.9 0.3 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT TPR_21 PF09976.9 OAJ28860.1 - 0.33 10.6 12.7 0.99 9.1 4.7 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 OAJ28860.1 - 0.44 11.5 12.9 3.7 8.6 1.4 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 OAJ28861.1 - 7.2e-52 175.6 1.6 1e-51 175.1 1.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ28861.1 - 1.1e-13 51.5 0.0 2.9e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain ANAPC8 PF04049.13 OAJ28861.1 - 0.093 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 RVT_1 PF00078.27 OAJ28862.1 - 3.7e-21 75.7 0.0 5.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 OAJ28862.1 - 0.0002 21.3 0.8 0.00055 19.9 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle Pribosyltran PF00156.27 OAJ28863.1 - 1.3e-15 57.3 0.1 1.7e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 OAJ28863.1 - 0.0045 16.4 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase zf-CCHC PF00098.23 OAJ28864.1 - 4.5e-06 26.5 1.9 4.5e-06 26.5 1.9 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ28864.1 - 0.065 13.1 0.4 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF5562 PF17717.1 OAJ28864.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5562) Copper-fist PF00649.18 OAJ28864.1 - 0.58 9.7 2.6 1.1 8.7 2.6 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain RVT_2 PF07727.14 OAJ28865.1 - 9.9e-69 231.7 0.0 1.4e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ28865.1 - 3.4e-16 59.5 0.1 1e-15 57.9 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ28865.1 - 0.00064 19.4 0.1 0.0086 15.8 0.3 2.7 2 1 0 2 2 2 1 Integrase core domain AMP-binding PF00501.28 OAJ28866.1 - 6.4e-86 288.6 0.0 7.6e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ28866.1 - 3.8e-11 43.8 0.1 9.6e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peripla_BP_6 PF13458.6 OAJ28866.1 - 0.042 13.5 0.1 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Periplasmic binding protein KptA_kDCL PF18176.1 OAJ28867.1 - 0.1 12.5 3.4 0.46 10.3 3.4 2.2 1 0 0 1 1 1 0 KptA in kinetoplastid DICER domain TFIIS_M PF07500.14 OAJ28868.1 - 6.1e-23 81.4 0.3 6.1e-23 81.4 0.3 2.3 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 OAJ28868.1 - 1.9e-18 66.0 7.7 3.3e-18 65.2 7.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 OAJ28868.1 - 2.5e-12 46.6 1.0 2.5e-12 46.6 1.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.12 OAJ28868.1 - 0.089 12.3 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-DNL PF05180.12 OAJ28868.1 - 0.27 11.2 2.1 0.53 10.3 2.1 1.4 1 0 0 1 1 1 0 DNL zinc finger KDZ PF18758.1 OAJ28869.1 - 5.7e-07 29.4 0.1 8.5e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase SLT_L PF14718.6 OAJ28869.1 - 0.15 12.2 0.6 2.8 8.1 0.0 2.4 1 1 1 2 2 2 0 Soluble lytic murein transglycosylase L domain DUF4482 PF14818.6 OAJ28870.1 - 0.19 12.6 4.0 0.1 13.5 1.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Phage_integrase PF00589.22 OAJ28871.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Vanabin-2 PF11437.8 OAJ28872.1 - 0.074 13.2 0.2 0.074 13.2 0.2 2.3 2 0 0 2 2 2 0 Vanadium-binding protein 2 Ins_beta PF03488.14 OAJ28872.1 - 0.077 13.0 0.8 0.077 13.0 0.8 2.2 2 0 0 2 2 2 0 Nematode insulin-related peptide beta type Pyridox_ox_2 PF12900.7 OAJ28874.1 - 5.5e-36 123.6 0.0 7.2e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DEAD PF00270.29 OAJ28875.1 - 2.4e-41 141.4 0.6 4.5e-41 140.5 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pyridox_ox_2 PF12900.7 OAJ28875.1 - 2.1e-15 56.9 0.1 4.7e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Helicase_C PF00271.31 OAJ28875.1 - 1e-09 38.7 0.2 2.9e-06 27.6 0.1 3.2 3 1 1 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ28875.1 - 8.6e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ28875.1 - 0.00018 21.8 0.2 0.0014 19.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ28875.1 - 0.0024 17.6 0.1 0.004 16.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 OAJ28875.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 OAJ28875.1 - 0.087 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 OAJ28875.1 - 0.14 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cutinase PF01083.22 OAJ28877.1 - 8.7e-23 81.2 0.0 1.1e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ28877.1 - 0.0032 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_8 PF06259.12 OAJ28877.1 - 0.021 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 OAJ28877.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 OAJ28877.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) ECR1_N PF14382.6 OAJ28877.1 - 0.04 13.7 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region LIP PF03583.14 OAJ28877.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase Cutinase PF01083.22 OAJ28878.1 - 3.5e-18 66.2 0.0 4.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Cutinase PF01083.22 OAJ28879.1 - 3.7e-20 72.6 0.1 4.6e-20 72.3 0.1 1.1 1 0 0 1 1 1 1 Cutinase FSH1 PF03959.13 OAJ28879.1 - 0.04 13.6 0.1 0.12 12.0 0.1 1.6 1 1 1 2 2 2 0 Serine hydrolase (FSH1) PE-PPE PF08237.11 OAJ28879.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 OAJ28879.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ28879.1 - 0.22 11.0 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GEMIN8 PF15348.6 OAJ28880.1 - 0.015 15.6 2.0 0.038 14.3 2.0 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Plasmodium_Vir PF05795.11 OAJ28880.1 - 0.087 12.2 1.3 0.15 11.5 1.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pox_Ag35 PF03286.14 OAJ28880.1 - 0.2 11.4 9.5 0.022 14.5 5.0 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4551 PF15087.6 OAJ28880.1 - 7.1 5.3 9.0 12 4.5 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Transposase_21 PF02992.14 OAJ28881.1 - 1.9e-14 53.5 0.4 4e-14 52.4 0.1 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ28881.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) BUD22 PF09073.10 OAJ28881.1 - 0.17 11.2 18.8 0.29 10.5 18.8 1.3 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 OAJ28881.1 - 0.75 9.7 6.5 1.4 8.9 6.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 OAJ28881.1 - 0.79 8.4 3.5 1.2 7.8 3.5 1.2 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 OAJ28881.1 - 1.7 6.9 8.4 2.4 6.3 8.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Spore_coat_CotO PF14153.6 OAJ28881.1 - 1.7 8.5 10.8 3.4 7.6 10.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.16 OAJ28881.1 - 7.9 5.6 10.0 15 4.7 10.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Clathrin PF00637.20 OAJ28882.1 - 2.7e-178 585.0 31.2 3.4e-31 108.0 0.0 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 OAJ28882.1 - 4.9e-32 109.7 0.1 8.6e-31 105.7 0.1 3.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 OAJ28882.1 - 3.5e-09 36.5 0.1 0.0002 21.5 0.0 2.6 2 0 0 2 2 2 2 Clathrin propeller repeat Clathrin-link PF09268.10 OAJ28882.1 - 1.1e-07 31.0 0.3 3.1e-07 29.6 0.3 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 OAJ28882.1 - 0.002 17.2 3.5 1.2 8.1 0.0 4.0 4 0 0 4 4 4 2 Coatomer WD associated region TPR_2 PF07719.17 OAJ28882.1 - 0.0069 16.4 14.7 7.5 6.9 0.1 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat Rbsn PF11464.8 OAJ28882.1 - 0.0096 15.6 0.9 0.5 10.1 0.0 3.7 3 0 0 3 3 3 1 Rabenosyn Rab binding domain TPR_7 PF13176.6 OAJ28882.1 - 0.065 13.3 11.3 39 4.6 0.1 6.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ28882.1 - 0.21 11.4 14.8 10 6.2 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ28882.1 - 0.27 11.6 8.5 17 5.9 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ28882.1 - 0.72 10.8 22.1 50 5.1 0.1 10.1 10 2 2 12 12 12 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ28882.1 - 1 10.1 3.4 1e+02 3.9 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ28882.1 - 5.2 7.4 9.7 63 4.0 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 OAJ28883.1 - 8.2e-13 48.6 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ28883.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ28883.1 - 7.9e-05 23.0 0.0 0.00013 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ28883.1 - 0.0029 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 OAJ28883.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 OAJ28883.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.31 OAJ28884.1 - 0.00017 21.6 0.1 0.00028 20.9 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 OAJ28884.1 - 0.00017 21.6 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Pam16 DUF4781 PF16013.5 OAJ28884.1 - 0.15 10.9 0.3 0.23 10.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Aminotran_1_2 PF00155.21 OAJ28887.1 - 2e-15 56.9 0.0 2.6e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 OAJ28887.1 - 8.8e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Glutaredoxin PF00462.24 OAJ28888.1 - 7.4e-18 64.5 0.0 1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 OAJ28888.1 - 0.00046 20.5 0.0 0.00054 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ28888.1 - 0.002 18.6 0.0 0.0045 17.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF953 PF06110.11 OAJ28888.1 - 0.0058 16.2 0.0 0.0067 16.0 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 OAJ28888.1 - 0.017 15.2 0.1 0.03 14.4 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 OAJ28888.1 - 0.038 14.1 0.2 7.3 6.7 0.2 2.1 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 OAJ28888.1 - 0.042 13.6 0.1 0.43 10.3 0.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TusA PF01206.17 OAJ28888.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Sulfurtransferase TusA Myb_DNA-binding PF00249.31 OAJ28889.1 - 8.4e-35 118.7 4.5 5.2e-12 45.8 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ28889.1 - 3.7e-27 94.3 0.0 2e-11 44.0 0.0 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 OAJ28889.1 - 0.0021 18.1 2.9 5 7.3 0.0 3.2 2 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 OAJ28889.1 - 0.0032 17.3 0.1 0.12 12.3 0.0 2.6 3 0 0 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 OAJ28889.1 - 0.09 13.0 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OAJ28889.1 - 0.12 12.7 0.9 15 6.0 0.0 2.9 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain GntR PF00392.21 OAJ28889.1 - 0.19 11.4 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family WD40 PF00400.32 OAJ28890.1 - 1.2e-25 89.2 0.2 4.5e-06 27.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28890.1 - 1.3e-09 38.3 0.0 0.0015 18.8 0.2 4.9 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ28890.1 - 0.0024 16.6 0.1 0.0042 15.8 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 OAJ28890.1 - 0.09 11.8 0.3 6.4 5.7 0.0 2.7 2 1 1 3 3 3 0 Coatomer WD associated region WD40_like PF17005.5 OAJ28890.1 - 0.2 11.0 0.0 2.3 7.4 0.0 2.6 3 1 1 4 4 4 0 WD40-like domain Ge1_WD40 PF16529.5 OAJ28890.1 - 0.27 10.1 1.3 4.5 6.1 0.3 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DPBB_1 PF03330.18 OAJ28891.1 - 7.5e-05 22.9 0.1 0.00019 21.6 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Gon7 PF08738.10 OAJ28891.1 - 0.0081 16.2 3.5 0.0081 16.2 3.5 1.9 2 0 0 2 2 2 1 Gon7 family SPESP1 PF15754.5 OAJ28891.1 - 0.16 11.2 11.2 0.21 10.8 11.2 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 SOG2 PF10428.9 OAJ28891.1 - 0.16 11.2 8.0 0.21 10.8 8.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2868 PF11067.8 OAJ28891.1 - 0.28 10.6 3.0 0.4 10.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TonB_N PF16031.5 OAJ28891.1 - 1.2 9.6 25.6 2.6 8.6 25.6 1.5 1 0 0 1 1 1 0 TonB polyproline region Menin PF05053.13 OAJ28891.1 - 2.7 6.3 10.0 3.8 5.8 10.0 1.2 1 0 0 1 1 1 0 Menin Lin-8 PF03353.15 OAJ28891.1 - 3.4 7.1 8.9 4.6 6.7 8.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mucin PF01456.17 OAJ28891.1 - 4.3 7.3 18.4 11 6.0 18.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIE-A_C PF11521.8 OAJ28891.1 - 5.7 7.3 14.4 1.5 9.2 1.1 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Apt1 PF10351.9 OAJ28891.1 - 7.2 5.3 13.4 9.3 5.0 13.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM154 PF15102.6 OAJ28891.1 - 8.4 6.3 8.9 18 5.3 8.9 1.4 1 0 0 1 1 1 0 TMEM154 protein family V-SNARE_C PF12352.8 OAJ28892.1 - 1.1e-17 64.0 7.6 2.4e-17 63.0 7.1 1.9 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 OAJ28892.1 - 5.4e-15 55.5 3.7 5.4e-15 55.5 3.7 3.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus PNK3P PF08645.11 OAJ28892.1 - 0.0063 16.2 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Prominin PF05478.11 OAJ28892.1 - 0.011 13.7 0.1 0.011 13.7 0.1 1.7 2 0 0 2 2 2 0 Prominin Fusion_gly PF00523.18 OAJ28892.1 - 0.07 11.4 0.2 0.12 10.5 0.2 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF5089 PF17002.5 OAJ28892.1 - 0.09 12.6 4.0 0.4 10.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5089) YnfE PF17452.2 OAJ28892.1 - 0.11 12.8 0.3 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized YnfE-like Fib_alpha PF08702.10 OAJ28892.1 - 0.12 12.6 6.5 0.89 9.7 2.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Orf78 PF06024.12 OAJ28892.1 - 0.53 10.6 2.0 1.7 8.9 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) YqjK PF13997.6 OAJ28892.1 - 0.64 10.3 3.5 0.63 10.3 0.5 2.4 2 0 0 2 2 2 0 YqjK-like protein TACC_C PF05010.14 OAJ28892.1 - 0.69 9.7 8.7 1.7 8.4 1.8 2.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sigma_reg_N PF13800.6 OAJ28892.1 - 1.3 9.3 4.0 2.3 8.6 4.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-CpG_bind_C PF12269.8 OAJ28892.1 - 2.4 7.9 4.8 2.2 8.0 0.2 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DUF4407 PF14362.6 OAJ28892.1 - 3.4 6.9 17.9 35 3.6 17.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3391 PF11871.8 OAJ28892.1 - 4.6 7.8 9.6 15 6.2 2.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Malate_DH PF12434.8 OAJ28892.1 - 6.3 6.9 7.2 1.5 8.9 0.4 3.0 3 0 0 3 3 3 0 Malate dehydrogenase enzyme Spc7 PF08317.11 OAJ28892.1 - 6.6 5.5 11.4 6.4 5.5 3.9 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein Methyltransf_23 PF13489.6 OAJ28893.1 - 9.9e-18 64.5 2.4 1.6e-17 63.8 2.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ28893.1 - 3.9e-16 59.5 0.0 4.9e-15 56.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ28893.1 - 3.3e-14 53.3 4.4 8e-13 48.9 0.1 3.1 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ28893.1 - 3.6e-14 52.8 0.1 4.3e-12 46.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ28893.1 - 3.1e-13 50.3 1.6 2.9e-12 47.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ28893.1 - 3.1e-06 26.7 0.1 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family MTS PF05175.14 OAJ28893.1 - 0.0007 19.2 1.4 0.022 14.3 0.1 2.8 1 1 2 3 3 3 1 Methyltransferase small domain NodS PF05401.11 OAJ28893.1 - 0.001 18.8 0.0 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 OAJ28893.1 - 0.002 17.2 0.0 0.0053 15.9 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase AlaDh_PNT_C PF01262.21 OAJ28893.1 - 0.0035 16.7 0.4 0.0055 16.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DREV PF05219.12 OAJ28893.1 - 0.0055 15.8 0.0 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase TehB PF03848.14 OAJ28893.1 - 0.007 15.8 0.0 0.91 8.9 0.0 2.1 1 1 1 2 2 2 2 Tellurite resistance protein TehB Dsh_C PF12316.8 OAJ28893.1 - 0.01 16.3 3.0 0.028 14.8 1.0 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal PCMT PF01135.19 OAJ28893.1 - 0.012 15.3 0.0 0.19 11.5 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 OAJ28893.1 - 0.038 12.9 0.0 0.71 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) TPMT PF05724.11 OAJ28893.1 - 0.074 12.7 0.0 0.13 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Zip PF02535.22 OAJ28893.1 - 0.98 8.6 12.9 1.3 8.1 12.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Gryzun PF07919.12 OAJ28894.1 - 7.7e-11 41.5 0.0 8.2e-05 21.6 0.1 2.3 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 OAJ28894.1 - 0.13 11.8 0.0 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 PPTA PF01239.22 OAJ28896.1 - 1.1e-41 139.4 17.5 1.2e-08 34.4 1.5 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DASH_Ask1 PF08655.10 OAJ28896.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 GalKase_gal_bdg PF10509.9 OAJ28897.1 - 2.5e-21 75.0 0.0 4.1e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 OAJ28897.1 - 8.9e-15 54.7 3.3 4.2e-14 52.5 1.4 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain Aconitase PF00330.20 OAJ28898.1 - 1.3e-148 495.8 0.0 1.8e-148 495.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ28898.1 - 1.2e-31 109.8 0.0 2.8e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain MRP-L28 PF09812.9 OAJ28898.1 - 0.0054 16.9 0.1 0.022 14.9 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L28 WIYLD PF10440.9 OAJ28898.1 - 0.12 12.2 0.3 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain CoA_transf_3 PF02515.17 OAJ28899.1 - 1.3e-63 215.4 0.0 2e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III MINDY_DUB PF04424.13 OAJ28904.1 - 1.6e-22 79.7 0.0 1.5e-21 76.6 0.0 2.3 2 1 0 2 2 2 1 MINDY deubiquitinase Tristanin_u2 PF16638.5 OAJ28906.1 - 0.0092 16.8 0.9 0.028 15.3 0.9 1.7 1 0 0 1 1 1 1 Unstructured region on methyltransferase between zinc-fingers GTSE1_N PF15259.6 OAJ28906.1 - 2 8.6 4.6 0.34 11.1 0.4 1.8 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 FoP_duplication PF13865.6 OAJ28906.1 - 2.3 8.8 8.6 4.6 7.9 8.6 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1764 PF08576.10 OAJ28907.1 - 9.7e-22 77.8 22.4 1.2e-15 58.3 22.4 2.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) SRP-alpha_N PF04086.13 OAJ28907.1 - 0.91 9.4 19.5 1.2 9.0 19.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LCD1 PF09798.9 OAJ28907.1 - 2.5 6.5 5.8 2.6 6.5 5.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein SOG2 PF10428.9 OAJ28907.1 - 3.5 6.7 14.7 4.4 6.4 14.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Zip PF02535.22 OAJ28907.1 - 5.1 6.2 6.0 5.6 6.1 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 OAJ28907.1 - 5.5 5.4 10.3 6 5.3 10.3 1.0 1 0 0 1 1 1 0 Macoilin family FAM220 PF15487.6 OAJ28907.1 - 6.3 6.3 12.3 7.9 6.0 12.3 1.2 1 0 0 1 1 1 0 FAM220 family DUF4551 PF15087.6 OAJ28907.1 - 6.6 5.4 12.3 7.4 5.3 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 OAJ28907.1 - 8.7 5.0 12.5 11 4.6 12.5 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ28907.1 - 8.8 6.1 13.9 12 5.7 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 OAJ28908.1 - 8.2e-14 51.8 0.6 3.3e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 OAJ28908.1 - 1.8e-13 50.8 0.0 3.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 OAJ28908.1 - 4.1e-08 33.8 4.1 0.00078 20.1 0.1 3.1 3 0 0 3 3 3 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 OAJ28908.1 - 5.6e-07 29.8 0.1 1.1e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 OAJ28908.1 - 4.5e-05 23.3 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sde2_N_Ubi PF13019.6 OAJ28908.1 - 0.071 12.9 0.6 0.19 11.5 0.6 1.8 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Cytochrom_C PF00034.21 OAJ28909.1 - 4.9e-11 43.6 0.0 6.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 OAJ28909.1 - 1.8e-07 31.4 2.1 1.8e-06 28.2 2.1 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 OAJ28909.1 - 0.0025 17.5 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 OAJ28909.1 - 0.085 13.5 0.0 0.091 13.4 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrome-c551 PF10643.9 OAJ28909.1 - 0.18 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 EOS1 PF12326.8 OAJ28910.1 - 1.3e-46 158.8 0.0 3.7e-45 154.0 0.0 3.2 2 2 0 2 2 2 1 N-glycosylation protein SUIM_assoc PF16619.5 OAJ28910.1 - 0.0069 16.4 1.3 0.0069 16.4 1.3 5.6 4 1 1 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 ARL6IP6 PF15062.6 OAJ28910.1 - 2.9 8.1 7.9 1.3 9.2 0.8 2.8 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix EMP24_GP25L PF01105.24 OAJ28911.1 - 7.3e-29 101.0 5.9 3.5e-15 56.4 2.0 2.0 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD eRF1_2 PF03464.15 OAJ28912.1 - 6.6e-44 149.5 0.0 1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 OAJ28912.1 - 3.6e-37 127.3 0.1 7.1e-37 126.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 OAJ28912.1 - 2.7e-18 66.2 0.0 4.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 OAJ28912.1 - 1.1e-10 41.9 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 OAJ28912.1 - 1.2e-08 35.3 0.0 2.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3600 PF12207.8 OAJ28912.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) DUF3440 PF11922.8 OAJ28912.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) TIP120 PF08623.10 OAJ28913.1 - 2.3e-55 186.9 7.5 1.1e-53 181.5 0.2 4.5 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 OAJ28913.1 - 3.1e-15 56.3 23.8 0.1 13.0 0.2 10.1 6 4 5 11 11 11 7 HEAT repeats HEAT PF02985.22 OAJ28913.1 - 6e-12 44.7 19.6 2.1 8.8 0.0 12.5 15 0 0 15 15 10 3 HEAT repeat HEAT_EZ PF13513.6 OAJ28913.1 - 9e-09 35.7 31.3 0.45 11.1 0.0 11.8 11 3 3 14 14 13 3 HEAT-like repeat Cnd1 PF12717.7 OAJ28913.1 - 3.5e-07 30.4 8.8 0.45 10.5 0.6 6.9 6 2 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ28913.1 - 1.6e-06 27.0 21.5 0.0013 17.4 0.7 6.5 2 2 2 5 5 5 3 Adaptin N terminal region UME PF08064.13 OAJ28913.1 - 3.6e-05 23.6 6.4 2.5 8.1 0.0 6.7 7 1 0 7 7 7 1 UME (NUC010) domain DUF3385 PF11865.8 OAJ28913.1 - 0.00044 20.2 9.3 0.18 11.7 0.3 5.5 7 0 0 7 7 6 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 OAJ28913.1 - 0.00078 20.0 0.8 3.2 8.4 0.1 6.7 8 1 2 10 10 6 1 Vacuolar 14 Fab1-binding region SIL1 PF16782.5 OAJ28913.1 - 0.0009 18.5 3.3 0.44 9.7 0.6 3.3 2 1 0 3 3 3 2 Nucleotide exchange factor SIL1 RTP1_C1 PF10363.9 OAJ28913.1 - 0.0016 18.6 8.1 0.56 10.4 0.1 6.7 6 1 3 9 9 9 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 OAJ28913.1 - 0.015 14.9 0.1 6.5 6.2 0.0 4.3 4 0 0 4 4 4 0 Tti2 family Ribosomal_S6 PF01250.17 OAJ28913.1 - 0.045 14.0 1.2 0.4 11.0 0.0 3.2 3 0 0 3 3 2 0 Ribosomal protein S6 ACDC PF14733.6 OAJ28913.1 - 0.076 13.3 1.2 45 4.4 1.2 4.0 2 1 0 2 2 2 0 AP2-coincident C-terminal Cnd3 PF12719.7 OAJ28913.1 - 0.33 10.1 3.4 16 4.6 0.0 4.6 4 1 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 OAJ28913.1 - 0.45 10.4 0.0 0.45 10.4 0.0 4.1 4 1 2 6 6 4 0 Domain of unknown function (DUF3361) BTV_NS2 PF04514.12 OAJ28913.1 - 0.45 9.3 4.7 0.81 8.5 4.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FANC_SAP PF18081.1 OAJ28913.1 - 1.1 9.5 3.3 4.3 7.6 0.3 3.7 3 0 0 3 3 2 0 Fanconi anemia-associated nuclease SAP domain RRN3 PF05327.11 OAJ28913.1 - 1.4 7.4 10.6 8.1 4.9 10.6 2.2 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 OAJ28913.1 - 2.5 8.0 13.5 0.8 9.6 3.1 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF3752 PF12572.8 OAJ28914.1 - 7.8e-13 49.2 38.3 3.9e-12 46.9 17.9 4.1 2 1 2 4 4 4 2 Protein of unknown function (DUF3752) Formyl_trans_N PF00551.19 OAJ28916.1 - 8.3e-32 110.4 0.0 1.1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 OAJ28916.1 - 7.6e-07 28.8 0.0 2.1e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 OAJ28916.1 - 0.00015 21.6 0.2 0.00045 20.1 0.0 1.8 2 0 0 2 2 2 1 ACT domain MDM10 PF12519.8 OAJ28917.1 - 8.1e-86 288.7 0.0 4.5e-58 197.3 0.0 2.8 2 1 0 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 OAJ28917.1 - 2.7e-05 23.8 0.1 0.00022 20.8 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic porin Septin PF00735.18 OAJ28918.1 - 2.6e-108 361.6 0.0 2.6e-108 361.6 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 OAJ28918.1 - 7.4e-08 32.5 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ28918.1 - 0.00064 19.3 2.7 0.0053 16.3 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 OAJ28918.1 - 0.00076 19.6 4.6 0.1 12.7 0.4 3.3 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 OAJ28918.1 - 0.0022 18.2 0.7 0.01 16.1 0.0 2.2 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.16 OAJ28918.1 - 0.0026 17.1 0.1 0.0053 16.1 0.1 1.6 1 1 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 OAJ28918.1 - 0.0034 16.8 0.4 0.0098 15.3 0.2 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 OAJ28918.1 - 0.0049 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ28918.1 - 0.0062 16.9 0.1 0.23 11.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain IIGP PF05049.13 OAJ28918.1 - 0.0067 15.5 0.1 0.016 14.3 0.1 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_28 PF13521.6 OAJ28918.1 - 0.0071 16.6 1.5 0.17 12.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ28918.1 - 0.0095 15.9 5.8 0.012 15.5 0.6 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 OAJ28918.1 - 0.011 16.1 1.0 0.03 14.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 OAJ28918.1 - 0.014 15.9 0.4 0.042 14.4 0.0 2.0 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 OAJ28918.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ28918.1 - 0.028 14.1 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 OAJ28918.1 - 0.037 13.8 0.3 1.4 8.7 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 OAJ28918.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 OAJ28918.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.22 OAJ28918.1 - 0.17 11.5 0.7 0.57 9.8 0.0 2.2 3 0 0 3 3 3 0 Ras family AAA_18 PF13238.6 OAJ28918.1 - 0.52 10.9 4.8 0.63 10.6 0.1 3.0 2 2 1 3 3 3 0 AAA domain DUF87 PF01935.17 OAJ28918.1 - 0.54 10.3 4.7 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 OAJ28918.1 - 9.4 6.7 17.2 3.7e+02 1.5 17.2 2.2 1 1 0 1 1 1 0 AAA domain Histone_H2A_C PF16211.5 OAJ28919.1 - 2.1e-18 65.7 0.8 4.8e-18 64.6 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ28919.1 - 9.9e-12 45.4 0.0 1.6e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Oxidored_FMN PF00724.20 OAJ28922.1 - 5.9e-43 147.4 0.0 3.2e-35 122.0 0.0 3.2 3 0 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 OAJ28922.1 - 0.014 14.9 0.0 3.8 6.9 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Dus PF01207.17 OAJ28922.1 - 0.2 10.7 0.1 0.54 9.3 0.1 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DnaJ_C PF01556.18 OAJ28923.1 - 3.2e-36 124.6 0.0 4.4e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ28923.1 - 3.5e-22 78.3 4.2 5.5e-22 77.7 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ28923.1 - 2.4e-09 37.4 17.9 3.2e-09 37.0 16.3 2.1 2 0 0 2 2 2 1 DnaJ central domain Binary_toxB PF03495.14 OAJ28923.1 - 0.21 11.8 0.9 7.7 6.8 0.3 2.6 2 1 1 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain K1377 PF15352.6 OAJ28923.1 - 0.86 7.8 6.3 1.1 7.4 6.3 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Anti-TRAP PF15777.5 OAJ28923.1 - 6.2 6.9 17.0 0.36 10.8 3.7 3.4 1 1 3 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein UQ_con PF00179.26 OAJ28924.1 - 8.8e-54 181.0 0.0 9.8e-54 180.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ28924.1 - 0.0077 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 OAJ28924.1 - 0.063 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 OAJ28924.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_C48 PF02902.19 OAJ28925.1 - 1.6e-25 90.2 0.0 4.6e-25 88.7 0.0 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SUR7 PF06687.12 OAJ28926.1 - 2.7e-21 76.2 4.4 3.4e-21 75.8 4.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Ost5 PF05251.12 OAJ28926.1 - 0.85 9.9 12.5 0.28 11.5 7.9 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF2207 PF09972.9 OAJ28926.1 - 2.4 6.8 6.0 3.6 6.2 6.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PhoLip_ATPase_C PF16212.5 OAJ28928.1 - 5.3e-75 252.4 22.7 1.1e-74 251.3 22.7 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ28928.1 - 1.6e-27 95.0 2.9 3.7e-27 93.8 2.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ28928.1 - 9.1e-12 44.9 0.0 4.1e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ28928.1 - 3.1e-11 44.0 1.6 2.2e-06 28.1 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ28928.1 - 1.7e-05 24.5 0.0 0.00015 21.4 0.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ28928.1 - 0.0033 17.2 0.1 0.014 15.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 2TM PF13239.6 OAJ28928.1 - 6.6 7.1 11.0 5.1 7.5 3.8 3.4 3 0 0 3 3 3 0 2TM domain PAP2_3 PF14378.6 OAJ28929.1 - 4.3e-21 75.5 14.5 4.3e-21 75.5 14.5 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 OAJ28929.1 - 6.6e-08 32.4 5.5 2.1e-07 30.8 5.5 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 OAJ28929.1 - 1.4 9.5 7.0 0.83 10.2 3.7 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Ribosomal_L37ae PF01780.19 OAJ28930.1 - 1.5e-40 137.2 8.8 1.6e-40 137.0 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 OAJ28930.1 - 0.0013 18.8 1.2 0.0019 18.3 1.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 OAJ28930.1 - 0.002 18.0 2.1 0.0033 17.4 2.1 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.15 OAJ28930.1 - 0.017 15.1 5.4 0.45 10.6 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.6 OAJ28930.1 - 0.078 13.4 7.6 0.34 11.4 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.11 OAJ28930.1 - 0.12 12.0 1.2 1 9.0 0.0 2.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) DUF2175 PF09943.9 OAJ28930.1 - 0.12 12.7 2.1 3.6 7.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) C1_2 PF03107.16 OAJ28930.1 - 0.54 10.6 3.7 1.6 9.1 3.8 1.7 1 1 0 1 1 1 0 C1 domain Zn_ribbon_SprT PF17283.2 OAJ28930.1 - 4.3 7.3 7.5 0.95 9.4 3.1 2.1 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Sec8_exocyst PF04048.14 OAJ28931.1 - 1.7e-34 118.7 0.3 4.7e-34 117.3 0.3 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 OAJ28931.1 - 4.5e-05 23.6 0.5 0.00052 20.1 0.1 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 OAJ28931.1 - 0.00069 19.0 0.8 0.0016 17.8 0.8 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 OAJ28931.1 - 0.0076 14.9 0.9 0.014 14.0 0.9 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 NAD_binding_10 PF13460.6 OAJ28931.1 - 0.039 13.8 4.4 0.33 10.8 0.1 3.6 4 0 0 4 4 4 0 NAD(P)H-binding Metal_resist PF13801.6 OAJ28932.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance GCH_III PF05165.12 OAJ28932.1 - 0.26 10.5 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase III Fe-ADH PF00465.19 OAJ28933.1 - 1e-66 225.2 0.0 1.4e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 OAJ28933.1 - 6.7e-16 58.7 0.7 1.5e-14 54.3 0.7 2.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 OAJ28933.1 - 0.027 13.6 0.0 1 8.4 0.0 2.3 2 0 0 2 2 2 0 3-dehydroquinate synthase PFK PF00365.20 OAJ28933.1 - 0.057 12.7 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphofructokinase Methyltransf_11 PF08241.12 OAJ28935.1 - 3.4e-06 27.6 0.1 2e-05 25.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ28935.1 - 2.3e-05 25.0 0.4 0.00085 20.0 0.3 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ28935.1 - 0.00034 20.4 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ28935.1 - 0.031 15.0 0.0 0.086 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF3663 PF12404.8 OAJ28935.1 - 0.38 10.8 2.4 0.58 10.2 0.6 2.0 2 0 0 2 2 2 0 Peptidase DUF4131 PF13567.6 OAJ28936.1 - 0.12 12.1 1.2 0.25 11.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 OAJ28936.1 - 0.45 10.8 15.1 1.3 9.3 8.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2070 PF09843.9 OAJ28936.1 - 6.6 4.9 11.7 0.78 8.0 5.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DUF3810 PF12725.7 OAJ28936.1 - 9.5 5.5 6.4 4.4 6.6 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DUF3915 PF13054.6 OAJ28937.1 - 0.34 10.9 10.1 0.63 10.0 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) CNH PF00780.22 OAJ28939.1 - 1.2e-80 271.1 0.0 2.1e-80 270.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 OAJ28939.1 - 4.4e-44 149.8 0.0 9e-44 148.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 OAJ28939.1 - 2.7e-37 128.8 0.6 4.2e-37 128.1 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ28939.1 - 6.2e-13 48.6 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 OAJ28939.1 - 0.0018 18.1 0.2 0.0087 15.9 0.1 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 OAJ28939.1 - 0.2 11.5 0.4 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 PH domain BolA PF01722.18 OAJ28940.1 - 3.2e-29 101.0 0.3 4.2e-29 100.6 0.3 1.2 1 0 0 1 1 1 1 BolA-like protein HATPase_c PF02518.26 OAJ28941.1 - 1.1e-18 67.7 0.2 4.1e-18 65.9 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ28941.1 - 2.3e-17 63.2 0.0 1.8e-10 41.0 0.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 OAJ28941.1 - 4.3e-16 58.7 0.1 1.2e-15 57.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Antibiotic_NAT PF02522.14 OAJ28941.1 - 0.002 18.0 0.6 0.0045 16.8 0.6 1.5 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase FSA_C PF10479.9 OAJ28941.1 - 0.47 8.5 8.4 1.3 7.0 8.4 1.7 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus p450 PF00067.22 OAJ28942.1 - 3.9e-54 184.1 0.0 4.7e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tim17 PF02466.19 OAJ28944.1 - 2.2e-25 89.2 6.1 2.2e-25 89.2 6.1 1.8 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family FxsA PF04186.13 OAJ28944.1 - 4.9 7.3 6.7 0.93 9.6 1.1 2.3 1 1 1 3 3 3 0 FxsA cytoplasmic membrane protein Golgin_A5 PF09787.9 OAJ28945.1 - 0.0037 16.8 8.0 0.0037 16.8 8.0 7.0 2 1 6 8 8 8 3 Golgin subfamily A member 5 SNARE PF05739.19 OAJ28945.1 - 0.61 10.1 2.5 1.4 9.0 0.4 2.9 2 0 0 2 2 2 0 SNARE domain FAM184 PF15665.5 OAJ28945.1 - 0.83 9.4 132.7 0.11 12.3 26.9 6.0 1 1 4 5 5 5 0 Family with sequence similarity 184, A and B Pkinase PF00069.25 OAJ28947.1 - 4.4e-58 196.7 0.0 5.6e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28947.1 - 1.9e-33 115.9 0.0 3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ28947.1 - 0.00011 22.3 0.1 0.00011 22.3 0.1 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ28947.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3584 PF12128.8 OAJ28947.1 - 0.068 10.7 11.9 0.11 9.9 11.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2203 PF09969.9 OAJ28947.1 - 0.69 10.6 7.1 0.24 12.1 3.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PNP_UDP_1 PF01048.20 OAJ28948.1 - 1.1e-35 123.0 0.6 1.3e-35 122.8 0.6 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Zn_clus PF00172.18 OAJ28949.1 - 0.0002 21.4 11.6 0.0002 21.4 11.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 OAJ28949.1 - 0.00031 20.7 0.0 0.00076 19.5 0.0 1.7 2 0 0 2 2 2 1 PAS fold LysM PF01476.20 OAJ28950.1 - 1.8e-05 24.7 0.1 6.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 LysM domain WD40 PF00400.32 OAJ28951.1 - 1.5e-19 70.0 13.4 3e-07 31.0 0.1 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28951.1 - 1.3e-08 35.1 0.2 0.11 12.8 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 OAJ28952.1 - 9.4e-63 212.0 0.3 1.5e-62 211.4 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ28952.1 - 3.2e-18 66.1 0.0 7.8e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 OAJ28952.1 - 1.4e-17 63.9 2.1 1.4e-17 63.9 2.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 OAJ28952.1 - 1.4e-13 50.5 1.5 1.4e-08 34.5 0.4 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 OAJ28952.1 - 7.6e-11 42.3 0.1 3.7e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 OAJ28952.1 - 3.6e-07 30.8 0.2 3.6e-07 30.8 0.2 3.1 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 OAJ28952.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 SLIDE Cdh1_DBD_1 PF18196.1 OAJ28952.1 - 0.067 13.5 0.1 0.067 13.5 0.1 4.5 4 0 0 4 4 4 0 Chromodomain helicase DNA-binding domain 1 TRAPP PF04051.16 OAJ28953.1 - 7.1e-35 119.9 0.0 8.7e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GCSF PF16647.5 OAJ28953.1 - 0.0028 17.5 0.4 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Granulocyte colony-stimulating factor MetallophosN PF16371.5 OAJ28953.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase TFIIIC_delta PF12657.7 OAJ28954.1 - 3.4e-05 23.8 0.2 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 OAJ28954.1 - 0.04 13.9 0.8 0.092 12.7 0.8 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TPT PF03151.16 OAJ28955.1 - 2.7e-44 151.6 12.0 5e-44 150.8 10.1 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ28955.1 - 3.1e-11 43.6 24.7 1.5e-07 31.7 7.2 2.6 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAJ28955.1 - 1.9e-08 33.9 10.8 2.9e-08 33.3 10.8 1.3 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 OAJ28955.1 - 9.1 7.0 12.8 0.21 12.3 4.9 2.4 3 0 0 3 3 3 0 Small Multidrug Resistance protein Chitin_synth_1 PF01644.17 OAJ28956.1 - 5e-78 260.7 0.0 9.6e-78 259.8 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ28956.1 - 6.7e-27 93.2 0.0 1.5e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ28956.1 - 2.1e-22 79.5 5.5 1.1e-16 60.6 0.0 2.6 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ28956.1 - 3.8e-05 23.7 6.0 0.00016 21.7 6.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 LRR19-TM PF15176.6 OAJ28956.1 - 0.012 15.5 0.2 0.052 13.6 0.2 2.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Spt20 PF12090.8 OAJ28956.1 - 8.4 5.9 14.9 14 5.2 14.9 1.2 1 0 0 1 1 1 0 Spt20 family Dicty_REP PF05086.12 OAJ28958.1 - 1 7.3 9.1 2.2 6.2 9.1 1.5 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 OAJ28959.1 - 1.9e-61 207.7 0.0 2.5e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28959.1 - 2.5e-39 135.1 0.0 3.3e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ28959.1 - 3.3e-06 26.6 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like F-box PF00646.33 OAJ28960.1 - 5.9e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ28960.1 - 0.056 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box SR-25 PF10500.9 OAJ28962.1 - 0.011 15.3 22.5 0.02 14.5 22.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_A12 PF04651.13 OAJ28962.1 - 0.064 13.3 9.4 0.1 12.6 9.4 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Lin-8 PF03353.15 OAJ28962.1 - 0.19 11.3 9.8 0.36 10.4 9.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sigma70_ner PF04546.13 OAJ28962.1 - 0.22 11.4 10.3 0.3 10.9 6.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region TAF4 PF05236.14 OAJ28962.1 - 0.25 11.1 13.9 0.36 10.5 13.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PI3K_1B_p101 PF10486.9 OAJ28962.1 - 0.39 8.4 13.9 0.54 8.0 13.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Miga PF10265.9 OAJ28962.1 - 0.47 9.4 5.5 0.63 8.9 5.5 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 OAJ28962.1 - 1.2 7.6 11.2 1.5 7.3 11.2 1.1 1 0 0 1 1 1 0 Macoilin family YL1 PF05764.13 OAJ28962.1 - 1.4 8.9 26.6 0.052 13.7 19.7 1.9 2 0 0 2 2 2 0 YL1 nuclear protein TRAP_alpha PF03896.16 OAJ28962.1 - 6 6.0 8.5 13 4.9 8.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MMU163 PF17119.5 OAJ28962.1 - 9 5.4 8.2 15 4.6 8.2 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis MOSC_N PF03476.16 OAJ28963.1 - 2.1e-17 63.1 0.0 4.1e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 OAJ28963.1 - 6.2e-17 61.8 0.0 1.2e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 MOSC domain AWS PF17907.1 OAJ28964.1 - 0.36 10.9 5.5 0.33 11.0 2.2 2.1 2 0 0 2 2 2 0 AWS domain zf-met PF12874.7 OAJ28964.1 - 0.62 10.5 0.1 0.62 10.5 0.1 2.6 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-RING_2 PF13639.6 OAJ28965.1 - 3.7e-09 36.8 0.6 3.7e-09 36.8 0.6 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 OAJ28965.1 - 4.1e-09 36.6 2.2 1.1e-08 35.2 2.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 OAJ28965.1 - 3.3e-06 27.2 0.9 3.3e-06 27.2 0.9 2.8 3 0 0 3 3 3 1 zinc-ribbon zf-C3HC4_2 PF13923.6 OAJ28965.1 - 3.1e-05 23.7 0.7 3.1e-05 23.7 0.7 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ28965.1 - 6.2e-05 22.8 0.2 6.2e-05 22.8 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ28965.1 - 8.3e-05 22.4 0.7 8.3e-05 22.4 0.7 2.1 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ28965.1 - 0.00013 21.9 5.7 0.00014 21.8 0.3 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ28965.1 - 0.0007 19.6 2.3 0.0022 18.0 2.3 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ28965.1 - 0.00087 19.1 2.2 0.00087 19.1 2.2 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ28965.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 2.8 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 OAJ28965.1 - 0.004 16.7 0.5 0.011 15.3 0.5 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ28965.1 - 0.0073 16.3 4.2 0.0084 16.1 1.5 2.4 1 1 1 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.8 OAJ28965.1 - 0.086 13.0 4.2 1.4 9.2 4.2 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 OAJ28965.1 - 0.16 11.8 1.1 0.4 10.6 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HypA PF01155.19 OAJ28965.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 OAJ28965.1 - 0.42 10.8 9.1 0.16 12.1 0.6 3.1 3 0 0 3 3 3 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 OAJ28965.1 - 0.51 10.4 2.6 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 OAJ28965.1 - 0.82 9.2 5.6 14 5.3 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 OAJ28965.1 - 1.6 8.8 7.1 4.1 7.5 0.3 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-C3H2C3 PF17122.5 OAJ28965.1 - 1.8 8.7 5.0 0.51 10.4 0.7 2.2 2 0 0 2 2 2 0 Zinc-finger 2-oxoacid_dh PF00198.23 OAJ28967.1 - 2.8e-79 265.8 0.0 4.6e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ28967.1 - 9.4e-19 67.0 1.7 1.8e-18 66.1 1.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ28967.1 - 0.00011 22.0 0.0 0.073 12.9 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 OAJ28967.1 - 0.0015 19.2 0.0 0.66 10.7 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 OAJ28967.1 - 0.014 15.3 0.5 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein NUDIX PF00293.28 OAJ28968.1 - 1.5e-15 57.4 0.0 5.7e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain DUF1770 PF08589.10 OAJ28969.1 - 0.00092 20.1 0.1 0.00092 20.1 0.1 2.2 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) Thiolase_N PF00108.23 OAJ28971.1 - 3.4e-79 265.9 2.3 4.5e-79 265.5 2.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ28971.1 - 4.9e-49 165.1 0.5 1.2e-48 163.8 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ28971.1 - 0.00016 21.3 1.7 0.00045 19.9 1.7 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF3915 PF13054.6 OAJ28972.1 - 0.14 12.2 2.4 0.32 11.0 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Yippee-Mis18 PF03226.14 OAJ28973.1 - 1.2e-14 54.4 0.4 1.3e-14 54.2 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 OAJ28973.1 - 0.017 15.4 0.6 0.024 14.8 0.6 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I HNH_5 PF14279.6 OAJ28973.1 - 0.029 14.2 0.1 4.8 7.1 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Extensin-like_C PF06904.12 OAJ28973.1 - 0.032 14.3 0.3 0.044 13.8 0.3 1.1 1 0 0 1 1 1 0 Extensin-like protein C-terminus Zn_ribbon_SprT PF17283.2 OAJ28973.1 - 0.11 12.4 3.3 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Endonuclease_7 PF02945.15 OAJ28973.1 - 0.2 11.6 2.4 0.62 10.0 2.4 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII UPF0047 PF01894.17 OAJ28974.1 - 2.6e-38 130.7 0.0 3.8e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Mito_carr PF00153.27 OAJ28975.1 - 4.1e-41 138.8 0.7 4.2e-14 52.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PQ-loop PF04193.14 OAJ28976.1 - 3.3e-29 100.4 0.9 1.4e-16 60.0 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 OAJ28976.1 - 0.027 15.3 0.8 2.5 8.9 0.3 2.4 1 1 0 2 2 2 0 ER lumen protein retaining receptor DDE_Tnp_4 PF13359.6 OAJ28978.1 - 8.8e-23 80.7 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Cwf_Cwc_15 PF04889.12 OAJ28979.1 - 0.1 12.3 13.0 0.24 11.1 13.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ28979.1 - 0.17 12.1 11.2 0.42 10.8 11.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 OAJ28979.1 - 0.26 10.6 12.0 0.43 9.8 12.0 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAJ28979.1 - 1.1 9.0 6.6 2.9 7.6 6.6 1.8 1 0 0 1 1 1 0 FAM176 family GCIP PF13324.6 OAJ28979.1 - 2 8.0 7.6 3.3 7.2 7.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 OAJ28979.1 - 2.3 6.3 10.2 3.5 5.7 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 OAJ28979.1 - 3.6 7.6 6.5 8.5 6.4 6.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 OAJ28979.1 - 3.9 8.2 12.9 13 6.6 12.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SH3_1 PF00018.28 OAJ28980.1 - 5e-14 51.6 0.2 1e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 OAJ28980.1 - 3.8e-13 49.8 0.0 7.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 OAJ28980.1 - 8.5e-11 41.5 0.1 1.7e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ28980.1 - 6.8e-08 32.1 0.0 1.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ28980.1 - 1.7e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ28980.1 - 5.3e-06 26.8 0.1 1.2e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 OAJ28980.1 - 0.0005 20.3 0.2 0.00092 19.4 0.2 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif WD40 PF00400.32 OAJ28981.1 - 3.8e-40 135.1 12.4 5.2e-07 30.3 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ28981.1 - 1.2e-13 51.2 0.0 0.00075 19.8 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 OAJ28981.1 - 0.00058 18.5 0.0 0.005 15.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 OAJ28981.1 - 0.0015 17.9 0.0 0.042 13.2 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 OAJ28981.1 - 0.0044 16.0 0.1 0.19 10.7 0.0 3.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 OAJ28981.1 - 0.031 12.6 0.0 0.071 11.4 0.0 1.5 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 OAJ28981.1 - 0.031 12.9 0.2 13 4.3 0.1 3.5 1 1 2 4 4 4 0 Nucleoporin Nup120/160 PD40 PF07676.12 OAJ28981.1 - 0.036 14.0 1.3 7.2 6.7 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 OAJ28981.1 - 0.093 13.3 3.3 1.1 9.9 0.5 3.7 3 1 0 3 3 3 0 PQQ-like domain Pkinase PF00069.25 OAJ28982.1 - 7.5e-21 74.7 0.0 3.7e-12 46.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ28982.1 - 6.7e-10 38.7 0.2 4.5e-08 32.7 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Gtr1_RagA PF04670.12 OAJ28983.1 - 1.3e-83 279.9 0.0 2e-83 279.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ28983.1 - 3.9e-07 30.3 0.0 9.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 OAJ28983.1 - 6e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 OAJ28983.1 - 0.0002 21.0 0.1 0.00043 19.9 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 OAJ28983.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OAJ28983.1 - 0.013 15.3 0.9 0.047 13.4 0.4 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAJ28983.1 - 0.039 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 OAJ28983.1 - 0.085 12.0 0.4 12 5.0 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 OAJ28983.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 OAJ28984.1 - 3.9e-07 30.6 2.9 0.11 13.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ28984.1 - 0.032 14.7 0.2 0.27 11.8 0.3 2.2 2 0 0 2 2 2 0 PQQ-like domain ANAPC4_WD40 PF12894.7 OAJ28984.1 - 0.18 12.1 0.0 1.7 9.0 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CRT10 PF08728.10 OAJ28984.1 - 0.3 9.2 0.0 0.4 8.8 0.0 1.1 1 0 0 1 1 1 0 CRT10 DUF3856 PF12968.7 OAJ28985.1 - 0.0087 16.1 1.5 5.2 7.1 0.2 3.3 3 0 0 3 3 3 2 Domain of Unknown Function (DUF3856) HTH_Mga PF08280.11 OAJ28985.1 - 0.12 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_14 PF13428.6 OAJ28985.1 - 2.7 9.1 5.6 25 6.0 0.9 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ28985.1 - 3.7 7.5 14.2 11 6.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.11 OAJ28986.1 - 1.6e-18 66.8 0.0 3.5e-17 62.4 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 OAJ28986.1 - 1.5e-05 24.7 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 OAJ28986.1 - 5.3e-05 23.8 0.0 0.00022 21.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ28986.1 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 OAJ28986.1 - 0.0002 21.3 1.3 0.00044 20.2 1.3 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_11 PF08241.12 OAJ28986.1 - 0.002 18.7 0.0 0.006 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 OAJ28986.1 - 0.0063 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 OAJ28986.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain MEF2_binding PF09047.10 OAJ28986.1 - 0.019 14.8 0.1 3.2 7.7 0.0 2.9 2 0 0 2 2 2 0 MEF2 binding PrmA PF06325.13 OAJ28986.1 - 0.028 13.8 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 OAJ28986.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein MSP1a PF11670.8 OAJ28986.1 - 0.48 9.7 6.3 0.96 8.7 6.3 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Aminotran_4 PF01063.19 OAJ28987.1 - 2e-26 93.3 0.0 5.7e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 Amino-transferase class IV SKN1 PF03935.15 OAJ28989.1 - 3.4e-182 606.3 0.5 4.3e-182 606.0 0.5 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OAJ28989.1 - 0.00033 20.2 0.0 0.02 14.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 DUF2673 PF10880.8 OAJ28990.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) SWIRM PF04433.17 OAJ28994.1 - 1.5e-30 105.4 0.0 3.1e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_2 PF16496.5 OAJ28994.1 - 3.9e-30 105.1 6.9 3.4e-21 75.6 1.8 3.5 4 0 0 4 4 4 3 SWIRM-associated domain at the N-terminal SWIRM-assoc_1 PF16495.5 OAJ28994.1 - 5.1e-29 100.1 5.4 1.7e-28 98.4 5.4 2.0 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 OAJ28994.1 - 2.7e-08 33.9 0.1 5.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 OAJ28994.1 - 2.5e-07 30.4 1.0 4.3e-07 29.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 OAJ28994.1 - 2.6e-07 30.8 0.0 7.5e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Calc_CGRP_IAPP PF00214.19 OAJ28995.1 - 0.067 13.6 0.1 0.075 13.4 0.1 1.3 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family ODC_AZ PF02100.17 OAJ28996.1 - 9.8e-11 41.6 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme LAGLIDADG_3 PF14528.6 OAJ29001.1 - 0.00018 21.7 0.0 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 LAGLIDADG-like domain Hom_end PF05204.14 OAJ29001.1 - 0.0085 16.3 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 1 Homing endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ29002.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain PCI PF01399.27 OAJ29004.1 - 1.1e-05 25.9 0.0 2.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain Dsh_C PF12316.8 OAJ29006.1 - 0.38 11.1 8.8 0.093 13.1 0.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF5543 PF17697.1 OAJ29007.1 - 0.05 13.9 0.2 0.062 13.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5543) Poxvirus_B22R PF04395.12 OAJ29007.1 - 0.17 11.4 0.3 0.26 10.8 0.3 1.6 1 1 0 1 1 1 0 Poxvirus B22R protein Dppa2_A PF14049.6 OAJ29008.1 - 0.061 13.5 6.4 0.25 11.5 6.4 2.1 1 0 0 1 1 1 0 Dppa2/4 conserved region in higher vertebrates Hydantoinase_B PF02538.14 OAJ29009.1 - 1.2e-211 703.6 0.1 1.6e-211 703.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PRIMA1 PF16101.5 OAJ29010.1 - 6.6 6.8 8.4 1 9.4 2.6 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF4381 PF14316.6 OAJ29012.1 - 0.046 14.0 0.0 0.046 14.0 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4381) DIL PF01843.19 OAJ29013.1 - 6.1e-27 93.9 1.0 1.2e-26 93.0 1.0 1.5 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 OAJ29013.1 - 6.3e-11 42.6 0.0 2.2e-09 37.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ29013.1 - 8.6e-11 42.3 0.0 5.8e-10 39.6 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ29013.1 - 6.5e-10 38.4 0.1 0.0007 19.9 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ29013.1 - 2.1e-07 31.1 0.0 2.2e-05 24.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ29013.1 - 4.6e-06 26.8 0.0 0.0031 17.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat DUF776 PF05604.11 OAJ29013.1 - 0.21 12.0 5.4 0.068 13.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF776) Yae1_N PF09811.9 OAJ29014.1 - 1.9e-07 30.7 4.8 3.7e-07 29.7 4.8 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 OAJ29014.1 - 0.00022 21.0 0.1 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.9 OAJ29014.1 - 0.18 12.2 6.3 0.38 11.1 6.3 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Zip PF02535.22 OAJ29014.1 - 0.21 10.8 4.7 0.33 10.1 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BORG_CEP PF14957.6 OAJ29014.1 - 1 10.5 7.0 0.52 11.5 3.5 2.2 2 0 0 2 2 2 0 Cdc42 effector CemA PF03040.14 OAJ29014.1 - 4.2 7.2 4.5 7.2 6.5 4.5 1.3 1 0 0 1 1 1 0 CemA family PAT1 PF09770.9 OAJ29014.1 - 4.9 5.3 27.5 8.2 4.6 27.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 OAJ29014.1 - 9.6 5.6 14.4 17 4.7 14.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin adh_short PF00106.25 OAJ29015.1 - 3.3e-36 124.6 0.1 4.7e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ29015.1 - 5.6e-29 101.4 0.3 9e-29 100.7 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ29015.1 - 7.7e-09 35.7 0.3 2.8e-08 33.9 0.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ29015.1 - 0.064 12.7 0.2 0.49 9.8 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family MmoB_DmpM PF02406.17 OAJ29015.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 MmoB/DmpM family AMP-binding PF00501.28 OAJ29016.1 - 2.8e-81 273.3 0.0 6.7e-58 196.3 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ29016.1 - 2.2e-11 44.5 0.0 5.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 OAJ29016.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF202 PF02656.15 OAJ29017.1 - 8.4e-19 67.8 1.4 1.5e-18 67.0 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF202) UPF0061 PF02696.14 OAJ29018.1 - 6.4e-85 285.7 0.0 1.5e-84 284.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Bac_luciferase PF00296.20 OAJ29019.1 - 1.8e-59 201.7 0.6 2.5e-59 201.3 0.6 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF5362 PF17319.2 OAJ29020.1 - 0.076 12.9 0.3 0.12 12.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5362) Saf_2TM PF18303.1 OAJ29021.1 - 0.025 14.2 0.2 0.039 13.5 0.2 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2755 PF10954.8 OAJ29021.1 - 0.027 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF4381 PF14316.6 OAJ29021.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) RIFIN PF02009.16 OAJ29021.1 - 0.55 10.1 9.8 0.55 10.1 0.2 2.1 1 1 0 2 2 2 0 Rifin DUF2749 PF10907.8 OAJ29021.1 - 0.7 10.1 6.3 1.3 9.2 0.9 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) PIRT PF15099.6 OAJ29021.1 - 5.2 6.7 9.9 19 4.8 9.9 1.8 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family C2 PF00168.30 OAJ29022.1 - 1.9e-12 47.4 0.0 5.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain 4HBT PF03061.22 OAJ29023.1 - 2.4e-08 34.2 0.0 3.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAJ29023.1 - 0.0037 17.5 0.0 0.0061 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily UQ_con PF00179.26 OAJ29024.1 - 2.2e-39 134.3 0.0 2.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ29024.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain MFS_1 PF07690.16 OAJ29025.1 - 1e-20 74.0 38.7 2.5e-13 49.7 22.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 OAJ29025.1 - 1.1e-11 44.7 5.2 1.1e-11 44.7 5.2 2.4 2 1 0 2 2 2 1 Nodulin-like zf-CCHH PF10283.9 OAJ29025.1 - 0.066 13.2 1.5 0.12 12.4 1.5 1.4 1 0 0 1 1 1 0 PBZ domain XFP_N PF09364.10 OAJ29027.1 - 3.4e-122 407.8 0.5 1.6e-101 339.8 0.1 2.2 2 0 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 OAJ29027.1 - 6.1e-66 221.7 0.0 1.4e-64 217.3 0.0 2.2 1 1 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 OAJ29027.1 - 1.3e-57 194.4 0.0 2.3e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 OAJ29027.1 - 0.011 15.5 0.3 0.026 14.3 0.3 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 OAJ29027.1 - 0.12 12.0 0.1 0.78 9.4 0.1 2.4 2 1 0 2 2 2 0 Transketolase, pyrimidine binding domain PI3_PI4_kinase PF00454.27 OAJ29028.1 - 8.1e-51 173.2 0.0 1.5e-50 172.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 OAJ29028.1 - 1.5e-32 113.2 0.0 3.7e-32 111.9 0.0 1.7 1 0 0 1 1 1 1 FAT domain UME PF08064.13 OAJ29028.1 - 9.9e-20 70.4 0.0 4.8e-19 68.2 0.0 2.4 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 OAJ29028.1 - 1.6e-07 31.0 0.0 6.5e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 FATC domain DUF241 PF03087.14 OAJ29028.1 - 0.0056 16.5 2.1 0.22 11.3 0.2 3.4 3 0 0 3 3 3 1 Arabidopsis protein of unknown function DUF3385 PF11865.8 OAJ29028.1 - 0.018 14.9 0.0 0.06 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 OAJ29028.1 - 0.11 13.1 9.0 1.3 9.6 2.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat DRMBL PF07522.14 OAJ29029.1 - 4.4e-27 94.5 0.0 9.4e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 OAJ29029.1 - 0.0052 16.8 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-C2HC_2 PF13913.6 OAJ29029.1 - 0.011 15.6 4.6 0.023 14.6 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CcdB PF01845.17 OAJ29029.1 - 0.029 14.6 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 CcdB protein Lactamase_B_2 PF12706.7 OAJ29029.1 - 0.035 13.6 0.0 0.28 10.7 0.0 2.4 3 0 0 3 3 3 0 Beta-lactamase superfamily domain Rad60-SLD_2 PF13881.6 OAJ29030.1 - 1.2e-10 41.4 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mucin PF01456.17 OAJ29030.1 - 2.1 8.3 8.7 3.6 7.6 8.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Efg1 PF10153.9 OAJ29031.1 - 9.1e-20 71.1 5.1 2.3e-19 69.9 5.1 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 NOA36 PF06524.12 OAJ29031.1 - 1.6 8.0 8.2 3.4 6.9 8.2 1.5 1 0 0 1 1 1 0 NOA36 protein CCDC-167 PF15188.6 OAJ29031.1 - 3 8.2 5.7 2.7 8.4 0.9 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.27 OAJ29032.1 - 2.7e-63 209.9 0.6 1.6e-24 85.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Rhomboid PF01694.22 OAJ29033.1 - 2.4e-08 34.1 14.7 0.00057 19.9 0.8 2.7 2 1 0 2 2 2 2 Rhomboid family Mitochondr_Som1 PF11093.8 OAJ29034.1 - 1.6e-09 37.6 0.3 2e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Mito_carr PF00153.27 OAJ29035.1 - 1.6e-54 181.8 3.3 2.5e-18 65.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.25 OAJ29037.1 - 1.4e-20 73.1 0.2 2.7e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 OAJ29037.1 - 8.5e-07 28.9 0.2 3.8e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Bromodomain associated EIF_2_alpha PF07541.12 OAJ29038.1 - 1.3e-35 122.0 0.0 2.1e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 OAJ29038.1 - 8.4e-14 51.7 0.2 1.9e-13 50.5 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 OAJ29038.1 - 0.049 13.0 0.1 0.066 12.5 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase family NIL PF09383.10 OAJ29038.1 - 0.11 12.3 0.1 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 NIL domain Histone PF00125.24 OAJ29039.1 - 2e-50 170.5 2.3 2.3e-50 170.4 2.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ29039.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ29039.1 - 0.00013 22.1 0.6 0.00019 21.5 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAJ29039.1 - 0.0004 21.0 1.4 0.00048 20.7 1.4 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 OAJ29039.1 - 0.029 14.6 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GDA1_CD39 PF01150.17 OAJ29040.1 - 5.4e-102 341.6 0.0 7.4e-102 341.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family CBX7_C PF17218.3 OAJ29040.1 - 2.8 7.8 4.4 5.6 6.8 4.4 1.5 1 0 0 1 1 1 0 CBX family C-terminal motif SNF2_N PF00176.23 OAJ29041.1 - 9.8e-40 136.3 0.0 1.7e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ29041.1 - 1.9e-18 66.8 0.0 6e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ29041.1 - 6.3e-07 29.6 0.0 2.3e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ29041.1 - 2.9e-05 23.9 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 OAJ29041.1 - 7.9e-05 22.0 0.0 0.00018 20.8 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 OAJ29042.1 - 3.5e-25 87.8 3.2 2e-06 28.4 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29042.1 - 1.8e-16 60.2 1.8 7.4e-05 23.0 0.1 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 OAJ29042.1 - 7.7e-06 25.9 0.1 5.2e-05 23.2 0.1 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PepSY_TM PF03929.16 OAJ29043.1 - 0.097 12.3 9.1 0.16 11.6 8.1 1.8 1 1 0 1 1 1 0 PepSY-associated TM region Phtf-FEM1B_bdg PF12129.8 OAJ29043.1 - 1.4 8.7 4.5 0.35 10.7 0.7 1.8 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Ribosomal_L34 PF00468.17 OAJ29044.1 - 4.9e-19 68.0 9.6 7.9e-19 67.4 9.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Ctr PF04145.15 OAJ29045.1 - 2.1e-37 129.0 3.2 5e-37 127.8 3.2 1.6 1 1 0 1 1 1 1 Ctr copper transporter family HHV-5_US34A PF17087.5 OAJ29045.1 - 0.15 12.2 0.5 0.15 12.2 0.5 2.2 2 0 0 2 2 2 0 Herpesvirus US34A protein family PE_PPE_C PF12484.8 OAJ29045.1 - 7.7 7.5 7.5 0.48 11.4 0.5 2.4 3 0 0 3 3 3 0 Polymorphic PE/PPE proteins C terminal Snf7 PF03357.21 OAJ29046.1 - 8.8e-44 149.1 12.4 8.8e-44 149.1 12.4 2.0 2 0 0 2 2 2 1 Snf7 Misat_Tub_SegII PF10644.9 OAJ29046.1 - 0.02 15.2 0.2 0.044 14.1 0.2 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ribosomal_60s PF00428.19 OAJ29046.1 - 0.095 13.3 2.6 2.4 8.8 0.1 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein TraC PF07820.12 OAJ29046.1 - 0.099 13.0 4.7 2 8.8 0.9 2.4 2 0 0 2 2 2 0 TraC-like protein DUF3138 PF11336.8 OAJ29046.1 - 0.27 9.8 3.4 0.26 9.9 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF5082 PF16888.5 OAJ29046.1 - 0.52 10.6 9.7 0.25 11.6 6.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Sin3_corepress PF08295.12 OAJ29046.1 - 2 8.5 4.8 0.4 10.8 0.4 2.1 3 0 0 3 3 3 0 Sin3 family co-repressor Dynamitin PF04912.14 OAJ29047.1 - 5.7e-16 58.8 0.0 8.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Dynamitin WD40 PF00400.32 OAJ29048.1 - 1.6e-36 123.6 11.1 1.8e-06 28.6 0.0 8.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29048.1 - 7.8e-18 64.6 0.1 0.0028 17.9 0.0 5.5 3 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 OAJ29048.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 OAJ29048.1 - 0.017 13.8 2.6 1.6 7.2 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 dUTPase PF00692.19 OAJ29049.1 - 9.6e-45 151.4 0.0 1.2e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase Ribosomal_S7 PF00177.21 OAJ29050.1 - 2.5e-36 124.6 1.2 3.2e-36 124.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SURF1 PF02104.15 OAJ29051.1 - 4.4e-40 137.8 0.0 6e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 SURF1 family VCPO_N PF17897.1 OAJ29051.1 - 0.0066 16.3 1.0 0.019 14.8 1.0 1.7 1 1 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PWWP PF00855.17 OAJ29052.1 - 7.2e-06 26.3 0.4 1.6e-05 25.2 0.4 1.5 1 0 0 1 1 1 1 PWWP domain ACOX PF01756.19 OAJ29053.1 - 1.7e-32 112.5 0.0 3.1e-32 111.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 OAJ29053.1 - 2.6e-07 31.0 0.0 8.3e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CDC50 PF03381.15 OAJ29054.1 - 2e-68 230.9 0.0 2.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PIP5K PF01504.18 OAJ29055.1 - 8.9e-38 130.1 0.0 2.1e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase p450 PF00067.22 OAJ29056.1 - 1.7e-44 152.3 0.0 2.5e-44 151.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SAP130_C PF16014.5 OAJ29056.1 - 0.09 11.9 4.2 0.15 11.1 4.2 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus RHH_4 PF13467.6 OAJ29056.1 - 0.11 12.4 0.8 1.2 9.1 0.4 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain Phasin_2 PF09361.10 OAJ29056.1 - 1.8 8.9 21.3 6.6 7.1 21.3 1.9 1 0 0 1 1 1 0 Phasin protein HAD PF12710.7 OAJ29057.1 - 4.3e-05 24.0 0.0 0.16 12.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SNARE_assoc PF09335.11 OAJ29058.1 - 1.4e-12 48.2 4.5 1.4e-12 48.2 4.5 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein Phage_holin_3_6 PF07332.11 OAJ29058.1 - 2.3 8.3 4.7 3.3 7.8 1.5 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III UPF0565 PF10561.9 OAJ29059.1 - 6.3 5.9 6.5 0.64 9.2 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 FKBP_C PF00254.28 OAJ29060.1 - 7e-34 116.0 0.0 8.1e-34 115.8 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 OAJ29062.1 - 3.6e-31 107.3 0.0 4.1e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Metallophos PF00149.28 OAJ29063.1 - 1.4e-10 42.0 0.0 2.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Linker_histone PF00538.19 OAJ29064.1 - 0.0091 16.3 0.0 0.11 12.9 0.0 2.3 1 1 0 1 1 1 1 linker histone H1 and H5 family DUF737 PF05300.11 OAJ29064.1 - 4.2 7.7 0.0 4.2 7.7 0.0 4.9 2 1 0 2 2 2 0 Protein of unknown function (DUF737) zf-RING_UBOX PF13445.6 OAJ29065.1 - 3.2e-06 27.1 1.2 7.8e-06 25.8 1.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ29065.1 - 5.1e-06 26.3 0.4 5.1e-06 26.3 0.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ29065.1 - 4.4e-05 23.3 6.5 0.00017 21.4 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ29065.1 - 6.8e-05 22.6 1.8 6.8e-05 22.6 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ29065.1 - 0.00053 19.9 2.7 0.0037 17.2 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ29065.1 - 0.0016 18.3 2.3 0.0035 17.2 1.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 OAJ29065.1 - 0.003 17.7 2.9 0.003 17.7 2.9 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ29065.1 - 0.0036 17.6 8.2 0.004 17.5 2.7 2.4 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 OAJ29065.1 - 0.0082 16.0 6.7 0.015 15.1 1.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Rhodanese PF00581.20 OAJ29066.1 - 1.5e-05 25.4 0.0 2.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain CBFB_NFYA PF02045.15 OAJ29067.1 - 6.6e-05 23.5 7.4 6.6e-05 23.5 7.4 2.8 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DNA_pol_phi PF04931.13 OAJ29067.1 - 5.7 4.9 6.4 9.8 4.1 6.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNase_H PF00075.24 OAJ29068.1 - 1.6e-08 34.9 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 RNase H Mito_carr PF00153.27 OAJ29069.1 - 9.9e-56 185.7 8.4 2.3e-22 78.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein TMEM126 PF07114.11 OAJ29069.1 - 0.0024 17.3 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 126 CTP_transf_like PF01467.26 OAJ29070.1 - 8.9e-08 32.4 0.0 2.3e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like FAD_syn PF06574.12 OAJ29070.1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD synthetase ANTH PF07651.16 OAJ29071.1 - 3.1e-70 236.3 0.2 3.1e-70 236.3 0.2 2.6 2 1 2 4 4 4 1 ANTH domain I_LWEQ PF01608.17 OAJ29071.1 - 3.3e-56 189.8 11.1 3.3e-56 189.8 11.1 5.4 5 1 1 6 6 6 2 I/LWEQ domain ENTH PF01417.20 OAJ29071.1 - 0.00012 22.1 3.0 0.00067 19.7 0.0 3.7 3 1 1 4 4 4 1 ENTH domain AMP-binding PF00501.28 OAJ29072.1 - 6.3e-68 229.3 0.0 9.5e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ29072.1 - 1.7e-20 73.8 0.2 4.5e-20 72.4 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HECT PF00632.25 OAJ29073.1 - 6.6e-97 324.7 0.0 8.4e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Tau95 PF09734.9 OAJ29073.1 - 0.14 13.0 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain adh_short PF00106.25 OAJ29074.1 - 1.9e-20 73.2 0.0 3.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ29074.1 - 3.6e-14 52.9 0.0 5.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ29074.1 - 0.00059 19.8 0.1 0.00082 19.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ29074.1 - 0.05 13.1 0.2 0.29 10.6 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 OAJ29074.1 - 0.092 12.1 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 OAJ29074.1 - 0.22 10.9 0.4 2.6 7.4 0.0 2.4 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Tudor_3 PF18115.1 OAJ29075.1 - 0.00017 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain SMN PF06003.12 OAJ29075.1 - 0.00055 19.3 0.0 0.00055 19.3 0.0 1.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) LBR_tudor PF09465.10 OAJ29075.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain PWWP PF00855.17 OAJ29075.1 - 0.0015 18.8 0.7 0.19 12.1 0.7 2.4 1 1 0 1 1 1 1 PWWP domain TUDOR PF00567.24 OAJ29075.1 - 0.0035 17.4 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Tudor_2 PF18104.1 OAJ29075.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain BRF1 PF07741.13 OAJ29075.1 - 0.22 11.9 4.0 19 5.7 3.0 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NAM-associated PF14303.6 OAJ29075.1 - 0.29 11.8 10.3 0.55 10.9 10.3 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Peptidase_S24 PF00717.23 OAJ29076.1 - 4.7e-05 23.3 0.2 0.00034 20.5 0.2 2.1 1 1 0 1 1 1 1 Peptidase S24-like Rhomboid PF01694.22 OAJ29077.1 - 1.3e-24 86.9 1.1 2.2e-24 86.2 1.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAJ29077.1 - 0.0029 18.1 0.1 0.024 15.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) RabGAP-TBC PF00566.18 OAJ29078.1 - 2.3e-49 167.9 0.0 4.3e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Metal_resist PF13801.6 OAJ29078.1 - 4.8 7.4 10.2 0.92 9.7 2.1 3.1 3 0 0 3 3 3 0 Heavy-metal resistance PfkB PF00294.24 OAJ29079.1 - 2.6e-40 138.6 0.1 3.4e-40 138.2 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Sugar_tr PF00083.24 OAJ29080.1 - 5.9e-47 160.5 13.6 7.4e-47 160.2 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29080.1 - 1.8e-24 86.3 25.6 7.2e-16 58.0 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ29080.1 - 0.046 12.0 3.3 0.37 9.0 0.0 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_C13 PF01650.18 OAJ29082.1 - 3.2e-43 148.1 0.4 4.5e-43 147.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase C13 family His_Phos_2 PF00328.22 OAJ29083.1 - 8.1e-46 157.1 0.0 2.5e-45 155.5 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-CCHC PF00098.23 OAJ29085.1 - 3.5e-12 45.8 16.9 0.00053 19.9 0.5 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ29085.1 - 0.00016 21.3 16.6 0.064 13.0 0.3 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ29085.1 - 0.00051 19.8 15.5 0.085 12.7 0.0 4.3 4 0 0 4 4 4 2 Zinc knuckle E7 PF00527.18 OAJ29085.1 - 0.12 12.6 0.2 0.52 10.5 0.2 2.1 1 0 0 1 1 1 0 E7 protein, Early protein zf-CCHC_6 PF15288.6 OAJ29085.1 - 0.25 11.2 0.1 0.25 11.2 0.1 4.7 5 0 0 5 5 5 0 Zinc knuckle PHD_4 PF16866.5 OAJ29085.1 - 1 9.5 7.7 0.93 9.6 0.4 3.2 2 1 1 3 3 3 0 PHD-finger zf-CCHC_3 PF13917.6 OAJ29085.1 - 5 7.2 10.0 12 6.0 0.4 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 OAJ29085.1 - 7.5 6.4 15.0 15 5.4 0.2 4.4 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger NDUF_B7 PF05676.13 OAJ29086.1 - 8.1e-06 25.5 2.6 1.2e-05 24.9 2.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 OAJ29086.1 - 1.2e-05 25.2 4.2 1.7e-05 24.8 4.2 1.2 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 OAJ29086.1 - 3.3e-05 24.0 2.3 4.6e-05 23.6 2.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type COX6B PF02297.17 OAJ29086.1 - 0.0035 17.5 2.6 0.0051 17.0 2.6 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 OAJ29086.1 - 0.01 16.1 1.9 0.016 15.5 1.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 ANATO PF01821.18 OAJ29086.1 - 0.19 12.6 1.8 0.25 12.2 0.6 1.8 1 1 0 1 1 1 0 Anaphylotoxin-like domain EamA PF00892.20 OAJ29087.1 - 1e-06 28.9 34.3 0.00032 20.9 6.4 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF1003 PF06210.11 OAJ29087.1 - 0.0012 18.9 0.4 0.0044 17.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) DUF3955 PF13127.6 OAJ29087.1 - 0.004 16.9 2.5 0.004 16.9 2.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) EPSP_synthase PF00275.20 OAJ29088.1 - 4.6e-108 361.6 0.0 6.6e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 OAJ29088.1 - 1.4e-96 322.7 0.0 4.4e-96 321.1 0.0 1.8 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 OAJ29088.1 - 6.6e-39 134.5 0.0 1.3e-38 133.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 OAJ29088.1 - 5.8e-23 81.0 0.0 2.3e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 OAJ29088.1 - 7.7e-21 74.9 0.0 5.9e-19 68.7 0.0 3.1 2 1 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 OAJ29088.1 - 4.9e-11 42.2 0.1 2.4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 OAJ29088.1 - 3e-05 24.1 0.0 6.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 OAJ29088.1 - 0.00033 20.5 0.4 0.00087 19.1 0.4 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 OAJ29088.1 - 0.044 12.6 0.9 0.16 10.7 0.9 1.9 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Asparaginase_C PF17763.1 OAJ29088.1 - 0.1 12.8 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain rRNA_proc-arch PF13234.6 OAJ29090.1 - 8.7e-75 252.1 0.5 1.3e-74 251.6 0.1 1.5 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 OAJ29090.1 - 8.7e-51 171.8 1.7 2.2e-50 170.5 1.7 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 OAJ29090.1 - 1.6e-18 67.1 0.0 6.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29090.1 - 1.3e-06 28.7 0.0 9.8e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 OAJ29090.1 - 0.098 11.7 0.1 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein IU_nuc_hydro PF01156.19 OAJ29091.1 - 2.8e-78 263.6 0.0 3.3e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SRF-TF PF00319.18 OAJ29091.1 - 0.22 11.0 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) VHS PF00790.19 OAJ29092.1 - 6.9e-41 139.4 0.0 1.9e-40 138.0 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 OAJ29092.1 - 1.2e-18 67.1 0.4 3.8e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 OAJ29092.1 - 0.85 9.3 4.0 1.5 8.5 0.2 2.9 3 0 0 3 3 3 0 GGA N-GAT domain Med3 PF11593.8 OAJ29092.1 - 3.3 6.8 15.6 0.26 10.5 9.6 1.9 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal GCP_N_terminal PF17681.1 OAJ29093.1 - 4.3e-61 207.2 0.0 1.4e-28 100.5 0.1 3.4 3 0 0 3 3 3 3 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ29093.1 - 8.4e-43 147.0 4.2 1.7e-42 146.0 4.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal YL1 PF05764.13 OAJ29093.1 - 5e-05 23.5 9.1 5e-05 23.5 9.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Nop53 PF07767.11 OAJ29093.1 - 0.00094 18.7 12.7 0.00094 18.7 12.7 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Apt1 PF10351.9 OAJ29093.1 - 0.021 13.7 0.3 0.046 12.6 0.3 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rrn6 PF10214.9 OAJ29093.1 - 0.2 10.1 3.6 0.38 9.2 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 OAJ29093.1 - 0.21 9.8 18.9 0.37 9.0 18.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4484 PF14831.6 OAJ29093.1 - 0.23 11.5 8.0 9.9 6.1 6.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Pes-10 PF07149.11 OAJ29093.1 - 0.38 9.7 7.9 0.64 9.0 7.9 1.3 1 0 0 1 1 1 0 Pes-10 SDA1 PF05285.12 OAJ29093.1 - 0.48 9.8 15.2 0.96 8.8 15.2 1.4 1 0 0 1 1 1 0 SDA1 Nucleoporin_FG PF13634.6 OAJ29094.1 - 0.0075 17.1 36.3 0.0075 17.1 36.3 3.8 2 1 2 4 4 4 3 Nucleoporin FG repeat region PAT1 PF09770.9 OAJ29094.1 - 8 4.6 38.0 11 4.1 38.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 OAJ29094.1 - 9.3 6.0 13.1 18 5.0 13.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HCO3_cotransp PF00955.21 OAJ29095.1 - 4.3e-56 190.8 16.0 1.5e-27 96.6 7.3 3.1 2 1 0 3 3 3 3 HCO3- transporter family CbtB PF09489.10 OAJ29095.1 - 0.22 11.7 1.5 17 5.6 0.1 3.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Acyl-CoA_dh_1 PF00441.24 OAJ29096.1 - 7.2e-45 152.9 4.8 7.2e-45 152.9 4.8 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ29096.1 - 2.6e-28 98.9 0.0 7.8e-28 97.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ29096.1 - 4e-24 84.7 0.1 7e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ29096.1 - 8.8e-22 77.8 2.2 8.8e-22 77.8 2.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain RasGAP PF00616.19 OAJ29097.1 - 2.2e-18 66.8 0.0 3.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 OAJ29097.1 - 5.7e-07 29.8 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF1115 PF06544.12 OAJ29098.1 - 3.4e-06 27.2 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) SR-25 PF10500.9 OAJ29098.1 - 7.3 6.1 9.1 11 5.5 1.4 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Acyl-CoA_dh_N PF02771.16 OAJ29099.1 - 7.6e-29 100.7 0.1 1.4e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 OAJ29099.1 - 1.4e-23 83.8 0.0 2.5e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ29099.1 - 1.9e-22 79.3 0.0 3.6e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ29099.1 - 0.00031 21.0 0.3 0.00031 21.0 0.3 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PTH2 PF01981.16 OAJ29101.1 - 1.1e-08 35.3 0.5 3.6e-08 33.7 0.5 1.8 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4527 PF15030.6 OAJ29101.1 - 0.031 13.7 0.6 0.068 12.6 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) AAA_2 PF07724.14 OAJ29102.1 - 3.3e-43 147.8 0.0 4.2e-40 137.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 OAJ29102.1 - 1.2e-28 99.0 0.4 1.2e-28 99.0 0.4 2.5 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 OAJ29102.1 - 2.6e-26 91.5 0.9 1.2e-25 89.4 0.1 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 OAJ29102.1 - 1.7e-19 70.5 0.0 5.5e-10 39.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ29102.1 - 4.1e-11 42.9 0.1 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ29102.1 - 7.6e-11 42.2 0.0 9.5e-06 25.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ29102.1 - 4.3e-08 33.7 10.1 0.00016 22.1 0.4 4.7 3 2 0 3 3 2 2 AAA ATPase domain TniB PF05621.11 OAJ29102.1 - 2.5e-06 27.0 0.0 0.00022 20.7 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 OAJ29102.1 - 4.4e-06 26.3 0.2 0.03 13.8 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 OAJ29102.1 - 2.5e-05 24.3 0.2 0.0074 16.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ29102.1 - 3.8e-05 23.5 0.0 0.07 12.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 OAJ29102.1 - 7.2e-05 22.8 0.1 0.55 10.1 0.0 3.3 3 0 0 3 3 3 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 OAJ29102.1 - 0.00011 21.7 0.0 0.26 10.6 0.0 3.3 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAJ29102.1 - 0.00013 21.3 0.0 0.071 12.4 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 OAJ29102.1 - 0.00019 21.5 0.0 0.39 10.7 0.0 3.5 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit DUF853 PF05872.12 OAJ29102.1 - 0.00042 19.0 1.6 0.22 10.0 0.0 2.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 OAJ29102.1 - 0.0005 20.4 9.1 0.097 12.9 0.1 5.2 4 3 0 4 4 3 1 AAA domain NACHT PF05729.12 OAJ29102.1 - 0.0005 20.0 0.2 0.8 9.6 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_6 PF12774.7 OAJ29102.1 - 0.00051 19.1 0.1 0.042 12.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 OAJ29102.1 - 0.00059 20.4 0.0 1.1 9.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 OAJ29102.1 - 0.00073 18.6 0.0 0.69 8.8 0.0 2.8 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 OAJ29102.1 - 0.0029 17.6 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAJ29102.1 - 0.0038 17.5 4.8 1.2 9.3 0.0 3.8 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 OAJ29102.1 - 0.0042 16.9 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OAJ29102.1 - 0.0048 16.0 0.0 0.062 12.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 OAJ29102.1 - 0.0048 17.3 0.1 3.5 8.1 0.0 2.9 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.6 OAJ29102.1 - 0.005 17.2 1.7 1 9.7 0.2 3.3 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ29102.1 - 0.0055 16.0 3.9 0.072 12.3 0.0 2.8 4 0 0 4 4 2 1 TIP49 P-loop domain CENP-F_leu_zip PF10473.9 OAJ29102.1 - 0.0056 16.7 10.6 0.013 15.6 10.6 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Torsin PF06309.11 OAJ29102.1 - 0.0063 16.6 0.0 0.047 13.8 0.0 2.1 2 0 0 2 2 2 1 Torsin SRP54 PF00448.22 OAJ29102.1 - 0.0081 15.8 0.2 2.9 7.5 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 OAJ29102.1 - 0.0098 16.1 1.4 7.9 6.6 0.1 3.6 3 0 0 3 3 3 0 AAA domain T3SS_needle_E PF08988.10 OAJ29102.1 - 0.017 15.2 2.1 0.42 10.8 0.9 3.4 2 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle AAA_24 PF13479.6 OAJ29102.1 - 0.039 13.7 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 OAJ29102.1 - 0.059 12.9 0.1 0.059 12.9 0.1 3.4 2 1 0 2 2 1 0 UvrD/REP helicase N-terminal domain AAA_3 PF07726.11 OAJ29102.1 - 0.063 13.1 0.1 0.61 10.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 OAJ29102.1 - 0.065 12.4 0.6 7.5 5.6 0.1 3.1 3 1 0 3 3 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 OAJ29102.1 - 0.13 11.7 0.1 13 5.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.17 OAJ29102.1 - 0.49 10.4 5.3 5.6 7.0 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Elong_Iki1 PF10483.9 OAJ29103.1 - 2e-12 47.3 0.4 1.4e-06 28.0 0.2 2.9 2 1 0 2 2 2 2 Elongator subunit Iki1 DUF1077 PF06417.12 OAJ29104.1 - 5.1e-47 158.7 0.6 7.1e-47 158.3 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF5589 PF17672.1 OAJ29104.1 - 0.027 14.4 0.0 0.49 10.3 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5589) Slu7 PF11708.8 OAJ29105.1 - 1.2e-103 346.5 20.4 1.2e-103 346.5 20.4 2.9 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Elongin_A PF06881.11 OAJ29106.1 - 1e-25 90.2 0.2 1.5e-25 89.7 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Zn_clus PF00172.18 OAJ29107.1 - 2.3e-06 27.6 9.1 4.1e-06 26.8 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAJ29107.1 - 0.77 9.3 10.9 2 8.0 10.9 1.6 1 0 0 1 1 1 0 Spt20 family LIM_bind PF01803.16 OAJ29107.1 - 1.7 8.1 6.0 0.4 10.2 2.1 1.8 2 0 0 2 2 2 0 LIM-domain binding protein tRNA_synthFbeta PF17759.1 OAJ29108.1 - 3.9e-44 150.7 0.0 7.7e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 OAJ29108.1 - 2.9e-29 101.1 0.1 1e-27 96.1 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 OAJ29108.1 - 1.7e-27 96.2 0.0 3.5e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 OAJ29108.1 - 6.5e-20 71.2 0.0 4.8e-18 65.2 0.0 2.7 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF382 PF04037.13 OAJ29110.1 - 2.1e-53 179.8 0.0 4e-53 178.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 OAJ29110.1 - 1.1e-18 66.8 4.6 2.3e-18 65.8 4.6 1.6 1 0 0 1 1 1 1 PSP PBP1_TM PF14812.6 OAJ29110.1 - 3.4 8.1 23.0 1.2 9.6 0.6 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin_4 PF13462.6 OAJ29111.1 - 1.7e-06 28.3 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Nas2_N PF18265.1 OAJ29112.1 - 9.8e-26 89.5 0.8 1.5e-25 88.9 0.8 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 OAJ29112.1 - 4.8e-09 35.9 0.1 9.6e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 OAJ29112.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 OAJ29112.1 - 0.0015 18.8 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 OAJ29112.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Cnd3 PF12719.7 OAJ29113.1 - 3.1e-77 259.7 0.0 3.2e-75 253.1 0.0 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 OAJ29113.1 - 0.00013 22.1 3.1 5 7.2 0.0 4.6 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ29113.1 - 0.00017 21.9 12.2 0.0015 18.8 0.8 5.3 5 1 1 6 6 6 2 HEAT repeats CLASP_N PF12348.8 OAJ29113.1 - 0.0025 17.4 0.5 5.6 6.4 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 OAJ29113.1 - 0.0068 16.6 10.5 19 5.9 0.1 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 OAJ29113.1 - 0.045 14.3 4.3 46 4.7 0.0 5.5 5 1 0 5 5 5 0 HEAT-like repeat RTP1_C1 PF10363.9 OAJ29113.1 - 0.37 11.0 2.6 2 8.6 0.0 3.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Homeodomain PF00046.29 OAJ29114.1 - 1.1e-18 66.8 4.9 2e-18 66.0 4.9 1.5 1 0 0 1 1 1 1 Homeodomain E1_dh PF00676.20 OAJ29115.1 - 7.2e-62 209.0 0.0 1.3e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 OAJ29115.1 - 5.4e-61 205.4 0.0 7.9e-61 204.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 OAJ29115.1 - 2.1e-50 170.4 0.0 4.1e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 OAJ29115.1 - 5.8e-15 54.6 0.2 1.3e-14 53.4 0.2 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus ACBP PF00887.19 OAJ29117.1 - 3.1e-23 81.8 0.0 4.9e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein YL1 PF05764.13 OAJ29117.1 - 0.042 14.0 5.3 0.06 13.5 5.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 OAJ29117.1 - 0.37 10.5 7.6 0.52 10.0 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ29117.1 - 1.1 8.5 8.1 1.7 7.9 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein PI3Ka PF00613.20 OAJ29118.1 - 1e-52 178.2 0.0 1.6e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 OAJ29118.1 - 3e-47 161.5 0.0 7.2e-33 114.4 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 OAJ29118.1 - 1.4e-33 115.7 0.0 2.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 OAJ29118.1 - 0.0057 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4135 PF13575.6 OAJ29118.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFIIA PF03153.13 OAJ29120.1 - 1.8 8.5 37.4 2.6 8.0 37.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP_sp32 PF07222.12 OAJ29120.1 - 5.7 6.3 8.2 9.3 5.6 8.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Transketolase_N PF00456.21 OAJ29122.1 - 9.8e-16 57.6 2.6 3.7e-14 52.4 2.6 2.2 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 OAJ29122.1 - 2.5e-11 43.5 0.0 8e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 OAJ29122.1 - 3.1e-05 23.7 0.1 7.5e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 OAJ29122.1 - 0.0012 19.1 0.1 0.0054 17.0 0.0 2.0 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II E1_dh PF00676.20 OAJ29122.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component TMEM214 PF10151.9 OAJ29122.1 - 0.087 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NUC205 PF08168.11 OAJ29122.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NUC205 domain TPP_enzyme_C PF02775.21 OAJ29122.1 - 0.14 12.0 0.2 0.58 9.9 0.1 2.1 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Elf1 PF05129.13 OAJ29123.1 - 2.3e-25 88.4 1.9 2.7e-25 88.2 1.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like ABC_membrane_2 PF06472.15 OAJ29124.1 - 4e-96 321.5 3.3 5.2e-96 321.2 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ29124.1 - 6.2e-20 72.1 0.0 2.1e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ29124.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ29124.1 - 0.013 16.0 4.1 0.11 13.0 4.1 2.3 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAJ29124.1 - 0.014 14.8 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 OAJ29124.1 - 0.048 13.6 0.3 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ29124.1 - 0.08 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 OAJ29124.1 - 0.093 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 OAJ29124.1 - 0.29 10.8 0.6 0.54 9.9 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain OMPdecase PF00215.24 OAJ29125.1 - 1.2e-74 250.7 0.0 1.5e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family WW PF00397.26 OAJ29126.1 - 1.6e-08 34.5 2.1 2.6e-08 33.8 2.1 1.4 1 0 0 1 1 1 1 WW domain Dynamin_M PF01031.20 OAJ29128.1 - 3e-101 338.4 0.0 1.4e-100 336.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ29128.1 - 5.7e-50 169.7 0.0 1.5e-49 168.3 0.0 1.7 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 OAJ29128.1 - 6.3e-30 103.2 5.2 6.3e-30 103.2 5.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAJ29128.1 - 0.062 13.4 0.0 0.29 11.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase Acetyltransf_1 PF00583.25 OAJ29129.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ29129.1 - 1.5e-06 28.2 0.1 2.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ29129.1 - 6.4e-06 26.5 0.2 1.2e-05 25.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ29129.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 OAJ29129.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1-E2_ATPase PF00122.20 OAJ29130.1 - 3.5e-20 72.3 0.0 7.7e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 OAJ29130.1 - 1.2e-17 64.9 0.0 2.1e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 OAJ29130.1 - 0.0028 17.4 0.0 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ29130.1 - 0.0042 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 OAJ29130.1 - 0.096 12.2 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase IPP-2 PF04979.14 OAJ29131.1 - 1.2e-15 58.4 15.0 2.9e-12 47.5 15.0 2.3 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) PhoD PF09423.10 OAJ29132.1 - 3.2e-104 348.7 3.6 4e-104 348.4 3.6 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 OAJ29132.1 - 6e-27 94.0 0.8 1.3e-26 93.0 0.8 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 OAJ29132.1 - 1.8e-08 34.9 3.5 1.8e-08 34.9 3.5 2.4 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HNH_2 PF13391.6 OAJ29132.1 - 0.033 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Forkhead PF00250.18 OAJ29133.1 - 1.6e-29 102.0 0.0 2.8e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Abhydrolase_1 PF00561.20 OAJ29134.1 - 1.2e-13 51.3 0.0 7.9e-10 38.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ29134.1 - 2.1e-11 44.9 0.0 2.9e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ29134.1 - 6.4e-10 38.7 0.0 4.8e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 OAJ29134.1 - 0.0012 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ29134.1 - 0.041 13.7 0.1 0.5 10.1 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 OAJ29134.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Esterase_phd PF10503.9 OAJ29134.1 - 0.14 11.7 0.1 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 OAJ29134.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Mito_carr PF00153.27 OAJ29135.1 - 3.4e-57 190.4 20.1 1.1e-22 79.8 0.0 4.6 4 1 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 OAJ29135.1 - 6.9e-05 22.1 0.2 0.00049 19.4 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 OAJ29135.1 - 0.00012 21.7 0.1 0.00065 19.4 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OAJ29135.1 - 0.00065 19.1 0.5 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 OAJ29135.1 - 0.0065 16.9 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair NOA36 PF06524.12 OAJ29135.1 - 9.1 5.5 6.0 19 4.5 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein Tubulin PF00091.25 OAJ29136.1 - 1.8e-60 204.5 0.0 2.9e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ29136.1 - 1e-45 155.0 0.0 1.6e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 OAJ29136.1 - 0.00034 20.3 0.0 0.00072 19.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ29136.1 - 0.18 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like ALG11_N PF15924.5 OAJ29137.1 - 2.6e-83 279.2 0.0 4.4e-83 278.5 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 OAJ29137.1 - 1.7e-14 53.7 0.0 6e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ29137.1 - 1.7e-06 28.5 0.1 9.5e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ29137.1 - 0.0039 17.2 0.6 0.01 15.8 0.6 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 DUF4477 PF14780.6 OAJ29138.1 - 0.063 12.9 0.2 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) FAM199X PF15814.5 OAJ29138.1 - 6 5.8 8.9 10 5.1 8.9 1.4 1 0 0 1 1 1 0 Protein family FAM199X IF-2B PF01008.17 OAJ29139.1 - 1.7e-34 119.3 0.3 6.4e-31 107.6 0.0 2.8 3 0 0 3 3 3 2 Initiation factor 2 subunit family Nop14 PF04147.12 OAJ29139.1 - 0.031 12.5 10.2 0.053 11.7 10.2 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ29139.1 - 0.81 8.1 12.0 1.5 7.3 12.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 OAJ29139.1 - 6.8 5.9 14.9 11 5.3 14.9 1.2 1 0 0 1 1 1 0 NOA36 protein DUF1244 PF06844.11 OAJ29140.1 - 0.04 14.1 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) RabGAP-TBC PF00566.18 OAJ29141.1 - 2.9e-22 79.4 3.1 5.4e-18 65.4 0.8 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MFS_1 PF07690.16 OAJ29142.1 - 1.2e-37 129.7 39.8 1.4e-31 109.7 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2484 PF10658.9 OAJ29142.1 - 0.009 16.3 4.0 0.009 16.3 4.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2484) DUF4023 PF13215.6 OAJ29142.1 - 0.32 11.0 0.5 3 7.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF3693 PF12472.8 OAJ29142.1 - 0.35 10.6 1.9 11 5.8 0.1 3.2 3 0 0 3 3 3 0 Phage related protein SNF2_N PF00176.23 OAJ29144.1 - 1.6e-57 194.8 0.1 2.5e-57 194.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ29144.1 - 6e-12 45.9 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XPG_I PF00867.18 OAJ29144.1 - 3.5e-06 27.3 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 XPG I-region zf-RING_5 PF14634.6 OAJ29144.1 - 3.6e-05 23.6 0.6 8.1e-05 22.5 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 OAJ29144.1 - 0.0017 18.3 0.2 0.0039 17.2 0.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ29144.1 - 0.0021 17.9 0.7 0.0021 17.9 0.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ29144.1 - 0.0034 17.2 1.9 0.0034 17.2 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) XPG_N PF00752.17 OAJ29144.1 - 0.0062 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain zf-C3HC4_3 PF13920.6 OAJ29144.1 - 0.0076 16.1 3.0 0.016 15.1 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ29144.1 - 0.0099 15.7 0.9 0.023 14.6 0.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 OAJ29144.1 - 0.016 15.6 1.0 0.039 14.3 1.0 1.6 1 0 0 1 1 1 0 Ring finger domain DUF5643 PF18705.1 OAJ29144.1 - 0.09 12.8 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5643) zf-C3HC4_4 PF15227.6 OAJ29144.1 - 0.097 12.9 1.6 0.34 11.1 1.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 5_3_exonuc PF01367.20 OAJ29144.1 - 0.11 13.1 0.0 0.45 11.1 0.0 2.0 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold ResIII PF04851.15 OAJ29144.1 - 0.35 10.8 4.5 1.1 9.2 0.1 3.1 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit Metallopep PF12044.8 OAJ29145.1 - 2.7e-85 286.6 0.0 5.4e-35 120.8 0.0 3.1 3 0 0 3 3 3 3 Putative peptidase family Peptidase_M66 PF10462.9 OAJ29145.1 - 0.0014 17.6 0.2 0.0025 16.8 0.2 1.3 1 0 0 1 1 1 1 Peptidase M66 Jacalin PF01419.17 OAJ29145.1 - 0.004 17.1 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain Peptidase_M10 PF00413.24 OAJ29145.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.6 1 1 0 1 1 1 0 Matrixin Choline_kinase PF01633.20 OAJ29146.1 - 1.1e-33 116.6 0.0 5.7e-22 78.3 0.0 2.8 3 0 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 OAJ29146.1 - 0.018 15.0 0.1 0.51 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family UnbV_ASPIC PF07593.12 OAJ29148.1 - 0.0098 15.8 0.1 0.025 14.5 0.1 1.7 1 0 0 1 1 1 1 ASPIC and UnbV GCV_T PF01571.21 OAJ29149.1 - 1.4e-84 283.5 0.0 1.7e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 OAJ29149.1 - 2.4e-21 75.4 0.0 5e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 OAJ29149.1 - 0.0022 18.2 0.0 0.0071 16.5 0.0 1.9 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family DUF4946 PF16304.5 OAJ29149.1 - 0.057 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Thymidylate_kin PF02223.17 OAJ29150.1 - 9.3e-45 152.6 0.0 1.2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 OAJ29150.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ29150.1 - 0.00055 20.1 0.5 0.013 15.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.10 OAJ29150.1 - 0.0021 17.5 0.0 0.005 16.3 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 OAJ29150.1 - 0.058 13.8 0.8 0.23 11.8 0.9 1.9 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 OAJ29150.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family tRNA-synt_1b PF00579.25 OAJ29151.1 - 8.9e-68 228.7 0.0 1.1e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RCC1 PF00415.18 OAJ29152.1 - 1.1e-15 58.0 12.6 0.00015 22.3 0.1 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ29152.1 - 1.2e-06 28.2 19.6 0.46 10.4 0.1 7.4 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat L51_S25_CI-B8 PF05047.16 OAJ29153.1 - 8.4e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain SR-25 PF10500.9 OAJ29154.1 - 1.6 8.3 26.1 2.7 7.6 26.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 OAJ29154.1 - 4.4 6.0 5.2 6.1 5.6 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Acatn PF13000.7 OAJ29155.1 - 1.3e-158 529.0 19.3 7e-79 265.8 12.3 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 HGWP PF03578.15 OAJ29157.1 - 0.15 11.6 0.2 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 HGWP repeat Pkinase PF00069.25 OAJ29158.1 - 3.9e-62 210.0 0.0 3.8e-61 206.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29158.1 - 4.1e-34 118.0 0.0 9.4e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 OAJ29158.1 - 7.6e-29 99.6 15.1 7.7e-16 58.0 7.4 2.9 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 OAJ29158.1 - 2.1e-20 72.3 22.8 2.1e-11 43.5 9.2 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 OAJ29158.1 - 7e-08 33.1 2.1 2.1e-07 31.5 2.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 OAJ29158.1 - 3.7e-05 23.9 0.1 7.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 OAJ29158.1 - 0.00074 18.9 0.0 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 OAJ29158.1 - 0.031 13.9 0.5 2.1 7.9 0.1 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 OAJ29158.1 - 0.29 11.5 17.6 0.51 10.7 3.7 2.4 2 0 0 2 2 2 0 C1 domain Uds1 PF15456.6 OAJ29158.1 - 1.2 9.4 8.5 0.95 9.6 2.5 2.7 2 0 0 2 2 2 0 Up-regulated During Septation DUF2937 PF11157.8 OAJ29158.1 - 3 7.5 6.9 4.7 6.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4407 PF14362.6 OAJ29158.1 - 3.8 6.8 8.2 11 5.2 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FYVE_2 PF02318.16 OAJ29158.1 - 5 7.4 15.8 25 5.1 6.7 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger DEAD PF00270.29 OAJ29160.1 - 7.9e-10 38.8 0.0 1.9e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29160.1 - 4.3e-07 30.3 0.0 1.7e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ29160.1 - 0.006 16.6 0.4 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NBD_C PF17042.5 OAJ29160.1 - 3.2 8.2 6.0 8.1 6.9 6.0 1.6 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain Astro_capsid_p PF12226.8 OAJ29161.1 - 0.051 12.7 8.0 0.069 12.3 8.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DBD_HTH PF18430.1 OAJ29161.1 - 0.068 13.0 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Putative DNA-binding domain Nop14 PF04147.12 OAJ29161.1 - 2.3 6.3 11.6 2.9 6.0 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 OAJ29161.1 - 3.1 6.9 5.0 4.5 6.4 4.5 1.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ABC2_membrane PF01061.24 OAJ29162.1 - 1.9e-38 132.0 18.9 1.9e-38 132.0 18.9 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 OAJ29162.1 - 9.6e-25 87.7 0.0 1.6e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ29162.1 - 1.6e-05 24.9 0.1 0.1 12.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 OAJ29162.1 - 5.7e-05 22.4 23.9 0.00013 21.2 23.9 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 OAJ29162.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 OAJ29162.1 - 0.035 14.7 0.0 0.068 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 OAJ29162.1 - 0.039 13.7 0.9 0.072 12.8 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ29162.1 - 0.094 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 OAJ29162.1 - 0.14 11.8 0.1 0.33 10.5 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ29162.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ29162.1 - 0.18 11.7 0.2 0.3 11.0 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 OAJ29162.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CENP-F_N PF10481.9 OAJ29162.1 - 0.59 9.7 1.2 0.87 9.2 1.2 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain EamA PF00892.20 OAJ29162.1 - 7.9 6.6 18.5 0.16 12.1 6.2 3.3 3 0 0 3 3 3 0 EamA-like transporter family DASH_Spc19 PF08287.11 OAJ29163.1 - 3.3e-05 23.8 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Spc19 Pkinase PF00069.25 OAJ29165.1 - 7.3e-54 182.9 0.0 1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29165.1 - 1.2e-18 67.3 0.0 2.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 OAJ29165.1 - 0.0051 16.4 0.1 0.0099 15.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 OAJ29165.1 - 0.031 14.2 0.9 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ29165.1 - 0.099 12.2 0.2 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Exo_endo_phos_2 PF14529.6 OAJ29166.1 - 7.4e-15 54.8 0.0 1.2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 OAJ29166.1 - 0.041 13.4 0.2 0.065 12.7 0.2 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cwf_Cwc_15 PF04889.12 OAJ29168.1 - 0.41 10.3 2.8 0.86 9.3 2.8 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNase_P_pop3 PF08228.11 OAJ29171.1 - 0.0028 17.7 0.0 2.7 8.0 0.0 2.5 2 0 0 2 2 2 2 RNase P subunit Pop3 FAM176 PF14851.6 OAJ29171.1 - 6.5 6.4 7.6 20 4.8 0.1 2.7 2 0 0 2 2 2 0 FAM176 family RP-C_C PF11800.8 OAJ29172.1 - 0.38 10.8 3.2 0.95 9.5 0.0 2.9 3 0 0 3 3 3 0 Replication protein C C-terminal region KRTAP PF11759.8 OAJ29172.1 - 9.7 6.8 25.4 3.3 8.3 4.5 2.3 2 0 0 2 2 2 0 Keratin-associated matrix eIF2_C PF09173.11 OAJ29173.1 - 6.7e-37 125.6 0.5 1.8e-36 124.2 0.5 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 OAJ29173.1 - 3.7e-22 78.8 0.6 5.3e-21 75.0 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ29173.1 - 8e-12 45.4 1.6 1.1e-11 44.9 0.4 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 OAJ29173.1 - 0.00041 20.3 0.2 0.0048 16.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 OAJ29173.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 OAJ29173.1 - 0.02 14.9 0.9 0.08 13.0 0.1 2.3 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Asp_Glu_race PF01177.22 OAJ29174.1 - 2.2e-07 31.0 0.2 4.9e-06 26.6 0.2 2.1 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase AroM PF07302.11 OAJ29174.1 - 0.093 12.1 0.1 0.18 11.2 0.1 1.4 1 1 0 1 1 1 0 AroM protein DDE_Tnp_4 PF13359.6 OAJ29177.1 - 1.4e-21 76.8 0.0 2.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 OAJ29177.1 - 2.3e-05 24.1 0.4 0.001 18.8 0.2 3.0 2 1 0 2 2 2 1 Transposase DDE domain API5 PF05918.11 OAJ29177.1 - 8.7 5.0 9.3 19 3.9 7.6 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Tautomerase_3 PF14832.6 OAJ29178.1 - 3.4e-37 127.7 0.0 4e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme DUF4718 PF15842.5 OAJ29179.1 - 1.9 8.2 6.2 1.7 8.4 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Serglycin PF04360.12 OAJ29180.1 - 0.07 13.1 1.3 0.22 11.5 1.3 1.8 1 0 0 1 1 1 0 Serglycin RhoGEF PF00621.20 OAJ29182.1 - 7.4e-40 137.1 0.1 1.8e-39 135.9 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 OAJ29182.1 - 9.6e-10 38.5 0.0 0.00021 21.2 0.0 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain PH PF00169.29 OAJ29182.1 - 0.00082 19.8 0.0 0.0038 17.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_2 PF08458.10 OAJ29182.1 - 0.03 14.7 0.1 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Arteri_nucleo PF01481.16 OAJ29182.1 - 0.13 12.6 1.4 0.34 11.2 1.4 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein Pannexin_like PF12534.8 OAJ29182.1 - 0.32 10.0 1.5 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Cwf_Cwc_15 PF04889.12 OAJ29182.1 - 2.6 7.7 16.9 6 6.5 16.9 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.28 OAJ29183.1 - 1.2e-17 63.2 0.3 1.3e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ29183.1 - 4.4e-17 61.7 0.1 3.9e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 OAJ29183.1 - 5.7e-16 58.4 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 OAJ29183.1 - 1.2e-09 37.7 0.0 0.0002 21.0 0.0 2.6 3 0 0 3 3 3 2 Variant SH3 domain WH2 PF02205.20 OAJ29183.1 - 4e-07 29.6 0.2 4e-07 29.6 0.2 2.4 2 0 0 2 2 2 1 WH2 motif EF-hand_1 PF00036.32 OAJ29183.1 - 0.075 12.6 0.0 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 EF hand AAA PF00004.29 OAJ29184.1 - 1.4e-40 138.8 0.0 3.2e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ29184.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ29184.1 - 6e-07 30.0 0.4 0.00014 22.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 OAJ29184.1 - 1.8e-06 27.8 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ29184.1 - 3.1e-06 27.2 0.1 3.8e-05 23.7 0.3 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ29184.1 - 3.8e-05 24.2 0.0 0.00079 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ29184.1 - 3.9e-05 23.8 0.0 0.00061 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ29184.1 - 4.4e-05 23.8 0.3 0.0044 17.3 0.3 2.9 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ29184.1 - 0.00022 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 OAJ29184.1 - 0.00049 20.3 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ29184.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 OAJ29184.1 - 0.0026 17.2 0.0 0.62 9.4 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 OAJ29184.1 - 0.0027 18.1 0.0 0.0093 16.4 0.0 1.9 1 1 1 2 2 1 1 RNA helicase TIP49 PF06068.13 OAJ29184.1 - 0.0028 16.9 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 OAJ29184.1 - 0.0034 16.8 0.2 0.011 15.1 0.1 1.7 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ29184.1 - 0.0042 16.8 0.1 0.0069 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 OAJ29184.1 - 0.0044 16.6 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 OAJ29184.1 - 0.0046 17.2 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 OAJ29184.1 - 0.0067 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 OAJ29184.1 - 0.0072 16.2 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial dnaA protein DUF815 PF05673.13 OAJ29184.1 - 0.0089 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 OAJ29184.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 OAJ29184.1 - 0.018 14.6 1.4 0.1 12.2 0.5 2.1 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 OAJ29184.1 - 0.021 14.2 0.0 0.14 11.5 0.0 2.1 1 1 1 2 2 2 0 KaiC Parvo_NS1 PF01057.17 OAJ29184.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 OAJ29184.1 - 0.023 14.6 0.1 0.17 11.8 0.1 2.3 2 1 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 OAJ29184.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 OAJ29184.1 - 0.047 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 OAJ29184.1 - 0.058 13.3 0.1 0.18 11.7 0.0 2.0 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 OAJ29184.1 - 0.065 13.1 1.0 4.3 7.2 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 OAJ29184.1 - 0.097 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein S1FA PF04689.13 OAJ29184.1 - 0.1 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 DNA binding protein S1FA AAA_21 PF13304.6 OAJ29184.1 - 0.11 12.2 0.5 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_11 PF13086.6 OAJ29184.1 - 0.12 12.1 0.1 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 OAJ29184.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase FCH PF00611.23 OAJ29184.1 - 0.14 12.5 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain IPT PF01745.16 OAJ29184.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase CPT PF07931.12 OAJ29184.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 OAJ29184.1 - 0.18 12.3 0.1 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 OAJ29184.1 - 0.18 11.7 0.3 0.48 10.3 0.1 1.8 2 0 0 2 2 1 0 NACHT domain DUF2075 PF09848.9 OAJ29184.1 - 0.23 10.7 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SAICAR_synt PF01259.18 OAJ29185.1 - 2.8e-91 305.6 0.0 5.3e-91 304.7 0.0 1.4 1 1 0 1 1 1 1 SAICAR synthetase Pro-kuma_activ PF09286.11 OAJ29185.1 - 0.11 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain SCA7 PF08313.12 OAJ29186.1 - 2.5e-25 88.2 0.2 5.3e-25 87.1 0.2 1.5 1 0 0 1 1 1 1 SCA7, zinc-binding domain MAS20 PF02064.15 OAJ29186.1 - 0.016 15.3 4.6 0.016 15.3 4.6 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor TAF4 PF05236.14 OAJ29186.1 - 0.26 11.0 13.4 0.021 14.6 6.3 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Rrn6 PF10214.9 OAJ29186.1 - 0.82 8.1 2.3 0.93 7.9 2.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S15 PF02129.18 OAJ29187.1 - 5.5e-08 32.7 0.1 1.3e-05 24.9 0.0 2.1 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 OAJ29187.1 - 6.8e-08 32.5 0.1 0.00023 20.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ29187.1 - 3.3e-07 29.8 0.1 0.00077 18.8 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 OAJ29187.1 - 0.031 13.9 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 OAJ29187.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PC_rep PF01851.22 OAJ29188.1 - 2e-42 141.5 22.4 1.2e-09 38.1 0.0 8.9 8 0 0 8 8 8 8 Proteasome/cyclosome repeat RPN2_C PF18004.1 OAJ29188.1 - 1.5e-40 138.7 0.2 1.5e-40 138.7 0.2 2.3 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 OAJ29188.1 - 1.3e-22 79.9 5.9 2.8e-14 53.3 0.0 4.9 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 OAJ29188.1 - 2.7e-05 24.0 2.7 1 9.8 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 OAJ29188.1 - 4.8e-05 23.8 5.5 2.8 8.5 0.1 5.8 5 1 1 6 6 6 3 HEAT-like repeat HEAT_PBS PF03130.16 OAJ29188.1 - 0.0042 17.6 2.1 71 4.5 0.0 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 OAJ29188.1 - 0.1 12.6 0.0 5.8 6.9 0.0 2.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 OAJ29188.1 - 0.14 12.7 6.9 3.7 8.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ29188.1 - 1.8 8.9 4.5 5.6 7.3 0.2 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3439 PF11921.8 OAJ29188.1 - 1.9 8.5 4.0 4.2 7.4 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Exonuc_VII_L PF02601.15 OAJ29189.1 - 0.08 12.5 3.1 0.16 11.5 3.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_M43 PF05572.13 OAJ29190.1 - 2e-07 31.1 0.0 2.9e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Oxidored-like PF09791.9 OAJ29190.1 - 1.4e-06 27.9 3.6 2.7e-06 27.0 3.6 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pro-kuma_activ PF09286.11 OAJ29191.1 - 4.8e-17 62.6 0.0 1e-16 61.5 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 OAJ29191.1 - 2.9e-10 39.9 2.6 2.9e-10 39.9 2.6 1.7 2 0 0 2 2 2 1 Subtilase family IPPT PF01715.17 OAJ29192.1 - 4e-42 144.6 0.0 1.7e-41 142.5 0.0 1.8 1 1 0 1 1 1 1 IPP transferase AAA_22 PF13401.6 OAJ29192.1 - 0.002 18.4 0.1 0.0064 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ29192.1 - 0.0035 17.9 0.1 0.039 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 OAJ29192.1 - 0.05 13.1 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Ploopntkinase3 PF18751.1 OAJ29192.1 - 0.056 13.3 0.3 1.6 8.6 0.0 2.5 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 OAJ29192.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 OAJ29192.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.17 OAJ29192.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAJ29192.1 - 0.081 13.3 0.1 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Fungal_trans PF04082.18 OAJ29193.1 - 7e-21 74.4 0.0 2.7e-20 72.5 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ29193.1 - 4.3e-07 29.9 8.0 4.3e-07 29.9 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 OAJ29194.1 - 2.5e-16 60.1 0.0 6.1e-13 49.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ29194.1 - 2.2e-15 56.6 0.0 6.8e-15 55.0 0.0 1.8 1 1 1 2 2 2 1 TAP-like protein Abhydrolase_6 PF12697.7 OAJ29194.1 - 2e-05 25.3 7.2 7.7e-05 23.4 2.1 2.8 2 1 1 3 3 3 1 Alpha/beta hydrolase family V4R PF02830.18 OAJ29194.1 - 0.15 12.1 0.5 0.38 10.8 0.1 1.9 1 1 1 2 2 2 0 V4R domain Dec-1 PF04624.14 OAJ29194.1 - 0.26 11.1 3.3 2.4 8.1 0.4 2.3 2 0 0 2 2 2 0 Dec-1 repeat PAP2 PF01569.21 OAJ29195.1 - 1.9e-17 63.3 4.8 1.9e-17 63.3 4.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily RecT PF03837.14 OAJ29195.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RecT family Aminotran_5 PF00266.19 OAJ29196.1 - 2.3e-35 122.2 0.0 2.6e-34 118.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Ig_4 PF16680.5 OAJ29196.1 - 0.17 12.2 0.0 4.4 7.6 0.0 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain LSM PF01423.22 OAJ29197.1 - 2.1e-17 62.6 0.0 2.8e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain Pkinase PF00069.25 OAJ29199.1 - 7.1e-68 228.8 0.0 8.8e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29199.1 - 4.6e-30 104.8 0.0 6.5e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 OAJ29199.1 - 0.0034 17.3 3.5 0.056 13.4 0.1 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ29199.1 - 0.047 12.6 0.0 0.09 11.7 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 OAJ29199.1 - 0.079 12.3 0.2 0.24 10.7 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PKcGMP_CC PF16808.5 OAJ29200.1 - 0.00011 22.0 11.9 0.0015 18.3 0.7 4.0 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4200 PF13863.6 OAJ29200.1 - 0.014 15.8 8.2 0.014 15.8 8.2 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 OAJ29200.1 - 0.02 15.8 6.6 0.02 15.8 6.6 4.3 4 1 0 4 4 4 0 cGMP-dependent protein kinase interacting domain KASH_CCD PF14662.6 OAJ29200.1 - 0.077 12.8 37.1 0.14 11.9 22.3 3.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Aminopep PF10023.9 OAJ29200.1 - 0.18 11.1 5.4 0.45 9.8 5.4 1.6 1 0 0 1 1 1 0 Putative aminopeptidase Fib_alpha PF08702.10 OAJ29200.1 - 2.3 8.4 16.6 25 5.0 0.1 4.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 OAJ29200.1 - 5.1 7.2 46.0 1.1 9.3 0.7 4.5 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein HOOK PF05622.12 OAJ29200.1 - 7.7 4.5 33.8 0.95 7.5 0.2 2.8 2 1 0 2 2 2 0 HOOK protein AAA_13 PF13166.6 OAJ29200.1 - 8.2 4.9 26.9 13 4.2 21.4 2.6 2 1 1 3 3 3 0 AAA domain RNA_pol_Rpc34 PF05158.12 OAJ29201.1 - 3.4e-77 260.1 9.1 3e-69 234.0 0.6 3.1 2 1 1 3 3 3 2 RNA polymerase Rpc34 subunit TrmB PF01978.19 OAJ29201.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB SOG2 PF10428.9 OAJ29201.1 - 2.1 7.4 53.5 0.13 11.4 36.5 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein U1snRNP70_N PF12220.8 OAJ29202.1 - 4.5e-23 81.7 6.6 7e-23 81.1 6.6 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PITH PF06201.13 OAJ29203.1 - 2e-18 67.0 0.0 4.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 PITH domain CK2S PF15011.6 OAJ29204.1 - 0.095 12.6 0.1 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate Ribonuclease_3 PF00636.26 OAJ29205.1 - 3.8e-28 98.2 0.0 5.5e-14 52.7 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ29205.1 - 5.7e-16 58.8 0.1 8.3e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.22 OAJ29205.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain tRNA-synt_1 PF00133.22 OAJ29206.1 - 6.9e-89 298.7 0.0 2.9e-82 276.8 0.0 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1 PF00133.22 OAJ29207.1 - 4.7e-18 64.8 0.1 5.6e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) CxC1 PF18802.1 OAJ29210.1 - 1.8e-10 40.9 0.1 3.3e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 OAJ29210.1 - 1.8e-10 40.8 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 OAJ29210.1 - 4.3e-07 30.1 0.1 9e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 OAJ29211.1 - 8.7e-10 39.0 0.6 0.00065 20.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Asp PF00026.23 OAJ29213.1 - 2e-32 112.9 4.9 1.2e-17 64.3 3.3 2.4 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ29213.1 - 1.2e-06 28.9 1.1 0.042 14.1 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal PBP PF01161.20 OAJ29216.1 - 5.7e-16 59.0 0.1 1.1e-15 58.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.32 OAJ29217.1 - 9.1e-54 178.2 16.0 2.4e-11 44.0 0.4 8.6 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29217.1 - 6.8e-14 51.9 0.9 9.8e-06 25.8 0.1 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ29217.1 - 1.6e-09 37.0 13.7 0.011 14.4 0.2 5.5 3 1 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 OAJ29217.1 - 0.00027 19.8 0.5 5 5.8 0.0 4.0 2 1 2 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 OAJ29217.1 - 0.028 13.0 0.0 1.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 OAJ29217.1 - 0.051 13.5 0.0 9.4 6.1 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 OAJ29217.1 - 0.24 9.7 0.0 1.1 7.5 0.0 2.0 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Enolase_C PF00113.22 OAJ29218.1 - 2.1e-141 470.4 0.2 2.7e-141 470.1 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 OAJ29218.1 - 4.1e-57 192.0 0.1 7.5e-57 191.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 OAJ29218.1 - 9.1e-09 35.2 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 OAJ29218.1 - 0.008 15.4 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus ANAPC10 PF03256.16 OAJ29219.1 - 5.4e-45 153.3 0.0 1e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) XRCC1_N PF01834.16 OAJ29219.1 - 0.056 13.4 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Spt20 PF12090.8 OAJ29219.1 - 1.2 8.7 7.3 1.6 8.3 7.3 1.2 1 0 0 1 1 1 0 Spt20 family Spt5_N PF11942.8 OAJ29219.1 - 3.4 8.7 10.4 0.13 13.3 2.2 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Chitin_synth_2 PF03142.15 OAJ29220.1 - 8.6e-236 783.6 0.2 8.6e-236 783.6 0.2 1.8 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.21 OAJ29220.1 - 1.4e-130 436.6 0.0 6.1e-117 391.6 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 OAJ29220.1 - 1.9e-15 56.5 0.2 8.7e-14 51.2 0.0 3.3 4 0 0 4 4 4 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 OAJ29220.1 - 8.6e-14 51.9 3.1 1.3e-13 51.3 1.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 OAJ29220.1 - 2.8e-11 43.4 0.5 3.6e-07 30.2 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 OAJ29220.1 - 3.5e-08 33.6 0.0 6.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ29220.1 - 0.0014 18.5 0.0 0.38 10.5 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 DEAD PF00270.29 OAJ29220.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 OAJ29220.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Lyase_aromatic PF00221.19 OAJ29221.1 - 7.8e-08 31.4 1.0 2.5e-05 23.1 0.9 2.8 2 1 0 2 2 2 2 Aromatic amino acid lyase TrpP PF17099.5 OAJ29221.1 - 0.046 13.5 0.1 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Tryptophan transporter TrpP IL32 PF15225.6 OAJ29222.1 - 0.00063 20.1 3.0 0.002 18.4 1.6 2.0 1 1 1 2 2 2 1 Interleukin 32 Ntox28 PF15605.6 OAJ29222.1 - 0.043 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial toxin 28 FlxA PF14282.6 OAJ29222.1 - 0.37 10.8 9.2 0.51 10.4 9.2 1.2 1 0 0 1 1 1 0 FlxA-like protein Ricin_B_lectin PF00652.22 OAJ29224.1 - 0.048 13.9 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Spin-Ssty PF02513.17 OAJ29224.1 - 0.18 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Spin/Ssty Family 2OG-FeII_Oxy_3 PF13640.6 OAJ29227.1 - 4.2e-08 34.0 0.3 1.2e-07 32.5 0.3 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 OAJ29227.1 - 0.011 16.3 0.1 0.032 14.9 0.0 1.8 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Helicase_C PF00271.31 OAJ29229.1 - 7.2e-16 58.5 0.0 1.4e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 OAJ29229.1 - 2e-12 47.4 0.0 2e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 OAJ29229.1 - 1.4e-07 31.5 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ29229.1 - 4.5e-06 27.0 0.0 1.4e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 OAJ29229.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_16 PF13191.6 OAJ29229.1 - 0.022 15.1 4.4 0.033 14.6 0.1 3.0 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 OAJ29229.1 - 0.047 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase PF06745.13 OAJ29229.1 - 0.06 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC ABC_membrane PF00664.23 OAJ29230.1 - 4.8e-112 374.1 23.0 3.4e-59 200.7 11.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ29230.1 - 1.9e-68 229.2 0.0 3.3e-33 115.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ29230.1 - 4.2e-17 62.3 1.1 9e-05 22.0 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 OAJ29230.1 - 3.4e-11 42.6 0.7 0.0015 17.4 0.1 4.2 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 OAJ29230.1 - 6.5e-08 32.2 0.7 0.0032 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ29230.1 - 1.3e-07 31.9 0.2 0.053 13.8 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 OAJ29230.1 - 1.3e-06 28.3 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAJ29230.1 - 1.6e-06 28.2 0.2 0.13 12.0 0.0 3.6 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ29230.1 - 2e-06 28.3 0.7 0.026 14.9 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 OAJ29230.1 - 6.7e-06 26.7 0.4 0.24 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAJ29230.1 - 9.5e-06 25.6 0.0 0.2 11.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 OAJ29230.1 - 2.5e-05 23.9 0.2 0.045 13.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 OAJ29230.1 - 5.4e-05 22.6 0.0 0.087 12.1 0.0 3.0 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 OAJ29230.1 - 0.00011 21.9 0.8 0.51 10.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 OAJ29230.1 - 0.00015 22.2 0.2 0.77 10.2 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 OAJ29230.1 - 0.00025 21.2 3.0 1.3 9.3 0.1 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 OAJ29230.1 - 0.0009 19.3 0.1 3.8 7.5 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 OAJ29230.1 - 0.001 19.2 0.2 2.4 8.2 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain G-alpha PF00503.20 OAJ29230.1 - 0.0015 17.8 0.0 0.82 8.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.6 OAJ29230.1 - 0.0032 18.0 0.0 6.8 7.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 OAJ29230.1 - 0.0049 16.6 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 OAJ29230.1 - 0.0051 16.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 OAJ29230.1 - 0.0088 16.1 0.0 5.8 7.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 OAJ29230.1 - 0.011 15.9 0.0 2.8 8.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ29230.1 - 0.018 14.3 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 OAJ29230.1 - 0.022 14.3 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ29230.1 - 0.029 14.7 0.0 7.4 7.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase APS_kinase PF01583.20 OAJ29230.1 - 0.032 14.1 0.1 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 OAJ29230.1 - 0.034 14.4 1.0 8.7 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 OAJ29230.1 - 0.043 13.6 0.0 2.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 OAJ29230.1 - 0.051 12.7 0.0 9.3 5.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAJ29230.1 - 0.1 12.3 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 OAJ29230.1 - 0.11 12.1 0.1 11 5.6 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 OAJ29230.1 - 0.12 12.8 0.3 31 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAJ29230.1 - 0.16 12.0 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 OAJ29230.1 - 0.2 11.0 0.8 8.2 5.7 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family IMS PF00817.20 OAJ29231.1 - 5.3e-39 133.6 0.0 1.2e-38 132.5 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ29231.1 - 8.7e-12 45.8 0.0 3.1e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 OAJ29231.1 - 2.1e-07 31.2 1.0 4.4e-07 30.2 1.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 OAJ29231.1 - 0.0015 17.9 0.6 0.06 12.8 0.2 3.7 3 0 0 3 3 3 1 Ubiquitin binding region DUF1805 PF08827.11 OAJ29231.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) TilS PF09179.11 OAJ29231.1 - 0.13 12.7 0.7 1.2 9.7 0.1 2.7 2 0 0 2 2 2 0 TilS substrate binding domain mCpol PF18182.1 OAJ29231.1 - 0.2 12.0 0.0 0.57 10.5 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain ABC_membrane_3 PF13748.6 OAJ29232.1 - 0.053 12.8 0.3 0.1 11.9 0.3 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Thioredoxin PF00085.20 OAJ29233.1 - 3.4e-26 91.2 0.0 1.6e-24 85.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 OAJ29233.1 - 3.3e-08 33.2 0.0 4.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 OAJ29233.1 - 0.0056 17.0 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ29233.1 - 0.0072 16.8 0.0 0.014 15.8 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ29233.1 - 0.048 13.5 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein AhpC-TSA PF00578.21 OAJ29233.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Mog1 PF04603.12 OAJ29234.1 - 2.1e-39 135.0 0.0 2.5e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein IMPDH PF00478.25 OAJ29235.1 - 2.4e-132 441.2 0.0 1.5e-131 438.5 0.0 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 OAJ29235.1 - 1.9e-18 66.6 0.0 2.2e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 OAJ29235.1 - 8.9e-11 41.7 3.2 5.7e-08 32.5 2.3 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAJ29235.1 - 6e-10 38.7 1.1 1.2e-09 37.7 0.7 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 OAJ29235.1 - 1.3e-07 31.4 3.1 3.6e-06 26.6 0.9 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 OAJ29235.1 - 1.7e-05 24.3 1.9 3e-05 23.5 1.9 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 OAJ29235.1 - 0.046 13.1 0.6 1.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator IGPS PF00218.21 OAJ29235.1 - 0.081 12.1 0.1 0.78 8.9 0.0 2.1 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Dus PF01207.17 OAJ29235.1 - 0.28 10.2 1.5 1.3 8.1 0.2 2.0 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) RMI1_N PF08585.12 OAJ29236.1 - 3.5e-40 138.1 0.1 5e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein Ciart PF15673.5 OAJ29236.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor BRCA2 PF00634.18 OAJ29237.1 - 0.25 11.0 2.2 0.48 10.1 2.2 1.4 1 0 0 1 1 1 0 BRCA2 repeat NAT PF04768.13 OAJ29238.1 - 7.5e-45 152.6 0.0 1.3e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 OAJ29238.1 - 9.5e-30 104.0 0.0 2.3e-29 102.7 0.0 1.7 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 OAJ29238.1 - 1.9e-22 80.0 0.0 4.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Arm PF00514.23 OAJ29238.1 - 0.47 10.6 0.0 0.47 10.6 0.0 3.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1917 PF08939.10 OAJ29239.1 - 1.4e-13 51.3 1.5 3e-13 50.3 0.9 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) Pep1_7 PF17232.2 OAJ29239.1 - 5.4 7.5 13.4 6.3 7.3 0.9 3.5 3 0 0 3 3 3 0 Elicitor peptide 1-7 Acetyltransf_8 PF13523.6 OAJ29240.1 - 1.5e-37 128.5 0.3 2.2e-37 127.9 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rcd1 PF04078.13 OAJ29241.1 - 1.6e-121 404.5 1.1 2.1e-121 404.1 1.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SUIM_assoc PF16619.5 OAJ29241.1 - 0.01 15.9 1.4 0.01 15.9 1.4 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Cupin_4 PF08007.12 OAJ29242.1 - 0.00064 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 OAJ29242.1 - 0.00084 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 OAJ29242.1 - 0.00084 19.0 0.2 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_8 PF13621.6 OAJ29242.1 - 0.001 18.9 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain PepSY_2 PF13670.6 OAJ29242.1 - 0.11 12.5 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AraC_binding PF02311.19 OAJ29242.1 - 0.13 12.2 0.6 0.36 10.7 0.6 1.8 1 1 0 1 1 1 0 AraC-like ligand binding domain Peptidase_M1_N PF17900.1 OAJ29243.1 - 3.4e-46 157.8 2.0 1.7e-42 145.7 0.1 2.2 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 OAJ29243.1 - 1.1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain HPTransfase PF10090.9 OAJ29243.1 - 0.065 13.0 0.1 1.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Cyclin_N PF00134.23 OAJ29244.1 - 4.5e-09 36.1 0.0 1.1e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 OAJ29244.1 - 0.0094 16.0 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 OAJ29244.1 - 0.22 11.6 0.5 37 4.4 0.1 2.8 2 1 0 2 2 2 0 Cyclin, C-terminal domain Neuraminidase PF18413.1 OAJ29244.1 - 5.9 6.5 6.5 20 4.8 0.5 2.6 2 1 1 3 3 3 0 Neuraminidase-like domain HABP4_PAI-RBP1 PF04774.15 OAJ29245.1 - 4.1e-13 50.2 2.2 4.1e-13 50.2 2.2 2.5 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Stm1_N PF09598.10 OAJ29245.1 - 0.00037 21.3 2.7 0.00037 21.3 2.7 5.8 5 1 0 5 5 5 1 Stm1 Methyltransf_33 PF10017.9 OAJ29246.1 - 1.3e-63 215.0 0.0 7.6e-52 176.4 0.0 2.3 2 0 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 OAJ29246.1 - 2.6e-17 63.3 1.7 4.4e-17 62.5 0.2 2.0 2 0 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 OAJ29246.1 - 5.3e-05 23.7 2.6 0.00013 22.4 0.9 2.6 3 0 0 3 3 3 1 DinB superfamily Ribosomal_S9 PF00380.19 OAJ29247.1 - 8.3e-31 107.0 0.3 9.5e-31 106.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S3_C PF00189.20 OAJ29248.1 - 7.4e-25 87.3 0.1 3.1e-24 85.3 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 OAJ29248.1 - 1.6e-08 34.2 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 KH domain tRNA_int_end_N2 PF12928.7 OAJ29249.1 - 2.2e-10 40.5 0.0 4.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 OAJ29249.1 - 0.00027 20.5 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain TFIIF_alpha PF05793.12 OAJ29250.1 - 0.23 10.0 11.0 0.34 9.5 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PIEZO PF15917.5 OAJ29250.1 - 0.88 9.0 4.6 1.4 8.3 4.6 1.3 1 0 0 1 1 1 0 Piezo NARP1 PF12569.8 OAJ29250.1 - 1.1 8.1 7.0 1.6 7.5 7.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nop14 PF04147.12 OAJ29250.1 - 1.6 6.8 13.8 2.1 6.4 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family MULE PF10551.9 OAJ29251.1 - 3.6e-11 43.3 0.0 1.2e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 MULE transposase domain CIA30 PF08547.12 OAJ29252.1 - 5.6e-20 72.0 0.0 4.5e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 OAJ29252.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Glyco_hydro_92 PF07971.12 OAJ29253.1 - 4.3e-09 35.8 0.0 7.2e-06 25.2 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Histone PF00125.24 OAJ29254.1 - 3.9e-46 156.6 2.4 4.4e-46 156.5 2.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ29254.1 - 1e-05 25.8 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 OAJ29254.1 - 3.5e-05 23.9 0.1 5.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 OAJ29254.1 - 0.0086 16.7 0.9 0.01 16.4 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain Pkinase PF00069.25 OAJ29255.1 - 5.3e-72 242.4 0.0 6.4e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29255.1 - 2.1e-40 138.6 0.0 2.6e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ29255.1 - 1.4e-08 33.9 0.0 2.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ29255.1 - 1.1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ29255.1 - 3.7e-06 26.4 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 OAJ29255.1 - 0.00065 19.3 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 OAJ29255.1 - 0.0023 17.9 0.0 0.0036 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Integrase_H2C2 PF17921.1 OAJ29255.1 - 0.27 11.4 0.9 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain ABC_membrane PF00664.23 OAJ29256.1 - 1.1e-77 261.4 19.8 8.3e-43 147.0 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ29256.1 - 2.8e-50 170.4 0.1 3.5e-31 108.5 0.2 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ29256.1 - 1.2e-06 28.1 0.1 0.009 15.5 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ29256.1 - 3.1e-05 24.4 1.0 0.019 15.3 0.5 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ29256.1 - 0.0001 22.3 0.4 0.17 11.9 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 OAJ29256.1 - 0.0012 18.8 0.1 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 OAJ29256.1 - 0.0016 18.6 0.8 0.37 10.8 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 OAJ29256.1 - 0.0045 17.1 0.3 0.59 10.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.17 OAJ29256.1 - 0.013 15.3 0.4 9.1 6.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 OAJ29256.1 - 0.018 14.7 0.8 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.6 OAJ29256.1 - 0.021 14.6 1.2 3 7.5 0.2 3.0 3 1 0 3 3 3 0 AAA domain T2SSE PF00437.20 OAJ29256.1 - 0.06 12.4 0.0 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 OAJ29256.1 - 0.21 10.3 0.6 1.4 7.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NmrA PF05368.13 OAJ29257.1 - 1.6e-36 126.0 0.2 1.9e-36 125.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ29257.1 - 9.8e-18 64.7 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Cys_Met_Meta_PP PF01053.20 OAJ29257.1 - 0.002 16.7 0.3 0.01 14.4 0.1 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme 3Beta_HSD PF01073.19 OAJ29257.1 - 0.0058 15.7 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ29257.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 KR domain Integrase_H2C2 PF17921.1 OAJ29258.1 - 3.8e-05 23.7 0.1 3.8e-05 23.7 0.1 2.2 2 0 0 2 2 1 1 Integrase zinc binding domain Utp21 PF04192.12 OAJ29258.1 - 0.026 14.1 8.0 0.057 12.9 1.3 2.3 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain Med3 PF11593.8 OAJ29258.1 - 0.1 11.8 20.2 0.13 11.5 6.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal FAM193_C PF15914.5 OAJ29258.1 - 0.24 11.2 0.4 0.48 10.2 0.4 1.4 1 0 0 1 1 1 0 FAM193 family C-terminal TFIIA PF03153.13 OAJ29258.1 - 0.28 11.2 33.5 0.28 11.1 14.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0560 PF10577.9 OAJ29258.1 - 1.1 7.7 21.2 0.15 10.6 7.6 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EPL1 PF10513.9 OAJ29258.1 - 1.4 9.3 11.0 1.1 9.7 3.0 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Presenilin PF01080.17 OAJ29258.1 - 1.5 7.5 6.7 11 4.6 3.3 2.2 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 OAJ29258.1 - 5.3 7.0 9.1 0.74 9.8 1.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 OAJ29258.1 - 7 6.5 15.9 0.62 10.0 5.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.6 OAJ29258.1 - 7.3 5.7 9.3 1 8.5 1.9 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus adh_short_C2 PF13561.6 OAJ29259.1 - 3.4e-45 154.4 0.0 4e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ29259.1 - 1.9e-36 125.4 0.0 2.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ29259.1 - 2.5e-09 37.3 0.1 3.1e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 OAJ29259.1 - 0.0017 17.8 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Nop14 PF04147.12 OAJ29260.1 - 0.032 12.5 5.8 0.039 12.2 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 OAJ29263.1 - 9.7e-32 108.5 7.0 2.1e-06 28.4 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29263.1 - 2.7e-06 27.6 0.0 0.14 12.5 0.0 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Pro_isomerase PF00160.21 OAJ29264.1 - 1.4e-14 54.7 0.0 1.9e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD eIF-5_eIF-2B PF01873.17 OAJ29265.1 - 3.2e-39 133.4 0.1 7.1e-39 132.3 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 OAJ29265.1 - 2.3e-18 66.1 0.2 1e-17 64.0 0.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4611 PF15387.6 OAJ29265.1 - 2.1 8.6 8.0 21 5.4 4.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF974 PF06159.13 OAJ29266.1 - 1.8e-42 145.8 0.0 1.2e-35 123.5 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF974) Med26 PF08711.11 OAJ29267.1 - 1.1e-09 38.2 0.1 4.6e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PH PF00169.29 OAJ29268.1 - 9.4e-40 135.4 1.5 1.7e-20 73.5 0.3 3.3 3 0 0 3 3 3 3 PH domain PH_3 PF14593.6 OAJ29268.1 - 1.1e-15 57.5 2.0 2.4e-07 30.8 0.4 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 OAJ29268.1 - 2.5e-13 50.4 10.7 7e-06 26.4 6.0 4.3 3 1 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 OAJ29268.1 - 1.5e-11 44.4 5.0 4.1e-07 30.2 1.3 3.0 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 OAJ29268.1 - 8e-07 29.5 7.6 0.0009 19.6 1.1 4.4 3 1 0 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.7 OAJ29268.1 - 0.0029 17.7 2.5 2.8 8.1 0.7 3.2 3 1 0 3 3 3 2 Meiotic cell cortex C-terminal pleckstrin homology Spt20 PF12090.8 OAJ29268.1 - 0.008 15.8 8.0 0.008 15.8 8.0 3.9 3 1 0 4 4 4 2 Spt20 family PH_2 PF08458.10 OAJ29268.1 - 0.054 13.8 0.0 5.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_4 PF15404.6 OAJ29268.1 - 3 7.6 11.9 0.94 9.2 0.1 4.1 4 0 0 4 4 4 0 Pleckstrin homology domain Roughex PF06020.11 OAJ29268.1 - 6.3 5.8 11.6 0.55 9.3 1.0 2.9 2 0 0 2 2 2 0 Drosophila roughex protein Cupin_8 PF13621.6 OAJ29269.1 - 7.5e-18 65.1 0.1 1.5e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 OAJ29269.1 - 8.4e-18 64.9 0.1 8.3e-17 61.7 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase DUF4743 PF15916.5 OAJ29270.1 - 1e-12 48.1 0.0 8.3e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 OAJ29270.1 - 2.2e-11 43.9 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SRP19 PF01922.17 OAJ29272.1 - 0.13 13.2 0.8 0.24 12.4 0.1 1.7 2 0 0 2 2 2 0 SRP19 protein Endonuc_Holl PF10107.9 OAJ29272.1 - 1.8 8.4 7.7 15 5.4 0.1 2.4 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase RVT_3 PF13456.6 OAJ29273.1 - 0.031 14.1 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ29273.1 - 0.033 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Vps36-NZF-N PF16988.5 OAJ29273.1 - 0.5 9.8 6.0 0.89 9.0 0.1 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-CCHC_4 PF14392.6 OAJ29273.1 - 5.3 6.9 7.1 0.36 10.6 1.5 1.9 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 OAJ29274.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29274.1 - 7.3e-13 48.4 0.0 1.9e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 OAJ29274.1 - 0.47 10.8 1.7 5.7 7.5 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat Peptidase_S9 PF00326.21 OAJ29275.1 - 8.4e-33 113.6 0.0 2.2e-32 112.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 OAJ29275.1 - 1.1e-05 25.1 0.0 8.8e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAJ29275.1 - 2.7e-05 23.5 0.1 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 OAJ29275.1 - 9.4e-05 22.4 0.0 0.00025 21.0 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 OAJ29275.1 - 0.0015 17.3 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 OAJ29275.1 - 0.0044 16.7 0.6 0.21 11.2 0.3 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ29275.1 - 0.011 16.4 0.8 0.011 16.4 0.8 2.5 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 OAJ29275.1 - 0.016 15.1 0.1 0.11 12.3 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2439 PF10382.9 OAJ29276.1 - 1.9e-11 44.1 0.1 3e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) AbrB_C PF18277.1 OAJ29276.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AbrB C-terminal domain FKBP_C PF00254.28 OAJ29277.1 - 5.3e-28 97.2 0.0 1.1e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 OAJ29277.1 - 5.2e-07 30.2 0.0 5.2e-07 30.2 0.0 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain ECM1 PF05782.11 OAJ29277.1 - 0.23 10.3 2.0 0.33 9.8 2.0 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) CC190 PF15768.5 OAJ29277.1 - 2.3 8.2 10.6 3.8 7.5 10.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 KH_1 PF00013.29 OAJ29278.1 - 2.9e-94 308.9 30.5 4.4e-13 48.9 0.1 15.8 16 1 0 16 16 16 11 KH domain KH_2 PF07650.17 OAJ29278.1 - 7.5e-11 41.7 24.1 0.43 10.4 0.4 9.2 9 0 0 9 9 9 6 KH domain KH_4 PF13083.6 OAJ29278.1 - 3.3e-06 26.9 19.5 0.082 12.8 0.1 8.9 7 1 2 9 9 9 2 KH domain SLS PF14611.6 OAJ29278.1 - 0.0051 16.7 9.8 25 4.6 0.2 6.0 5 1 0 6 6 6 1 Mitochondrial inner-membrane-bound regulator acVLRF1 PF18859.1 OAJ29278.1 - 0.081 13.2 2.0 0.54 10.6 0.6 3.2 2 0 0 2 2 2 0 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family5 PF18846.1 OAJ29278.1 - 0.095 12.9 1.4 9.7 6.4 0.0 3.7 4 0 0 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 5 DDE_3 PF13358.6 OAJ29279.1 - 1.8e-14 53.7 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 OAJ29279.1 - 7.6e-10 38.9 2.8 7.6e-10 38.9 2.8 2.9 3 0 0 3 3 3 1 Transposase HTH_Tnp_ISL3 PF13542.6 OAJ29279.1 - 7.6e-06 25.3 2.1 0.00017 20.9 0.0 3.3 3 0 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 OAJ29279.1 - 9.7e-06 25.2 1.7 4.9e-05 23.0 0.1 2.8 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 OAJ29279.1 - 3.1e-05 23.7 0.0 7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.7 OAJ29279.1 - 9.8e-05 22.5 0.5 0.042 14.0 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.13 OAJ29279.1 - 0.00031 20.3 0.0 0.00072 19.1 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain GerE PF00196.19 OAJ29279.1 - 0.0013 18.2 0.1 0.0051 16.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_50 PF18024.1 OAJ29279.1 - 0.0029 17.2 0.1 0.0079 15.8 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 OAJ29279.1 - 0.0082 16.2 0.1 0.023 14.8 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 OAJ29279.1 - 0.022 15.1 0.6 0.044 14.1 0.2 1.8 2 0 0 2 2 1 0 Transposase HTH_29 PF13551.6 OAJ29279.1 - 0.025 14.6 0.1 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4_2 PF08281.12 OAJ29279.1 - 0.039 13.6 0.3 0.21 11.3 0.1 2.4 2 0 0 2 2 1 0 Sigma-70, region 4 HTH_32 PF13565.6 OAJ29279.1 - 0.041 14.5 4.1 0.11 13.1 0.4 3.1 2 1 1 3 3 3 0 Homeodomain-like domain YdaS_antitoxin PF15943.5 OAJ29279.1 - 0.084 12.7 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_7 PF02796.15 OAJ29279.1 - 0.11 12.6 0.5 1.5 9.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_3 PF01381.22 OAJ29279.1 - 0.11 12.6 0.3 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix Wbp11 PF09429.10 OAJ29279.1 - 0.12 12.7 5.8 0.14 12.6 4.3 2.0 2 0 0 2 2 1 0 WW domain binding protein 11 HTH_31 PF13560.6 OAJ29279.1 - 0.15 12.4 0.9 0.76 10.2 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain BRO1 PF03097.18 OAJ29280.1 - 1.1e-19 70.6 0.0 3.2e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 BRO1-like domain ABATE PF07336.11 OAJ29280.1 - 0.89 10.2 0.0 0.89 10.2 0.0 3.6 4 1 0 4 4 4 0 Putative stress-induced transcription regulator DPBB_1 PF03330.18 OAJ29282.1 - 3.6e-09 36.8 0.0 5.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Redoxin PF08534.10 OAJ29283.1 - 2e-06 27.6 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ29283.1 - 2.6e-05 24.1 0.0 0.00011 22.1 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family DOR PF14839.6 OAJ29284.1 - 0.15 12.0 8.5 0.074 13.0 1.2 2.6 2 1 0 2 2 2 0 DOR family Phage_integrase PF00589.22 OAJ29285.1 - 0.0062 16.3 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MULE PF10551.9 OAJ29287.1 - 2e-22 79.4 0.2 5e-22 78.1 0.1 1.8 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.18 OAJ29287.1 - 1.7e-08 33.7 0.0 2.3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Transposase, Mutator family Spt5_N PF11942.8 OAJ29288.1 - 0.031 15.2 9.9 0.058 14.4 9.9 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF874 PF05917.11 OAJ29288.1 - 0.16 11.0 7.9 0.2 10.7 7.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) CDC45 PF02724.14 OAJ29288.1 - 0.22 9.8 6.2 0.27 9.5 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 OAJ29288.1 - 0.35 8.9 2.8 0.36 8.9 2.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 OAJ29288.1 - 0.51 9.1 5.6 0.52 9.0 5.6 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 OAJ29288.1 - 0.86 9.6 6.6 1.4 9.0 6.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Neur_chan_memb PF02932.16 OAJ29288.1 - 0.93 9.5 6.3 1.2 9.1 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Coilin_N PF15862.5 OAJ29288.1 - 4.8 7.0 16.1 2.3 8.0 13.2 1.7 2 0 0 2 2 2 0 Coilin N-terminus zf-CHY PF05495.12 OAJ29289.1 - 5.6e-13 49.2 12.0 1.3e-12 48.0 12.0 1.6 1 1 0 1 1 1 1 CHY zinc finger HypA PF01155.19 OAJ29289.1 - 0.061 13.4 1.4 0.061 13.4 1.4 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cys_rich_KTR PF14205.6 OAJ29289.1 - 0.12 12.1 4.1 0.11 12.3 1.1 2.1 2 0 0 2 2 2 0 Cysteine-rich KTR SP2 PF03014.14 OAJ29289.1 - 0.3 9.5 0.9 0.36 9.2 0.9 1.1 1 0 0 1 1 1 0 Structural protein 2 Elf1 PF05129.13 OAJ29289.1 - 0.54 10.4 9.5 0.11 12.6 5.8 1.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 OAJ29289.1 - 1.1 9.5 11.2 0.13 12.4 1.3 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Sugar_tr PF00083.24 OAJ29290.1 - 2.4e-88 297.0 16.7 2e-72 244.5 3.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29290.1 - 1e-21 77.3 15.8 1e-21 77.3 15.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3809 PF12723.7 OAJ29290.1 - 0.018 15.4 0.2 0.035 14.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) COX16 PF14138.6 OAJ29291.1 - 8e-27 93.6 0.1 1.6e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Evr1_Alr PF04777.13 OAJ29291.1 - 1.1e-23 83.6 0.0 2.6e-23 82.4 0.0 1.7 2 0 0 2 2 2 1 Erv1 / Alr family KH_1 PF00013.29 OAJ29292.1 - 1.2e-46 156.3 9.3 2e-17 62.8 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ29292.1 - 1.7e-15 56.6 5.3 3.2e-05 23.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ29292.1 - 8.2e-06 25.6 1.5 1 9.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ29292.1 - 0.0095 16.0 8.0 0.42 10.7 0.2 3.6 3 1 0 3 3 3 2 NusA-like KH domain Sugar_tr PF00083.24 OAJ29294.1 - 3.1e-122 408.7 21.2 3.6e-122 408.5 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29294.1 - 2.8e-21 75.8 40.9 8.9e-20 70.9 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 OAJ29294.1 - 1.8 8.4 5.1 2.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RVT_2 PF07727.14 OAJ29295.1 - 1.4e-70 237.7 0.0 1.9e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ29295.1 - 9.5e-21 74.2 0.0 3.2e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ29295.1 - 5.2e-06 26.2 0.0 5.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ29295.1 - 8e-05 22.3 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Transcript_VP30 PF11507.8 OAJ29295.1 - 0.079 13.0 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 DUF3128 PF11326.8 OAJ29296.1 - 0.0053 17.1 0.1 0.0086 16.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DNA_pol_E_B PF04042.16 OAJ29297.1 - 1.2e-38 132.7 0.0 2.5e-38 131.6 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 OAJ29297.1 - 2.3e-38 131.2 0.0 3.7e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF4611 PF15387.6 OAJ29297.1 - 6.5 7.1 14.5 0.36 11.1 4.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mito_carr PF00153.27 OAJ29298.1 - 7.4e-36 122.0 3.8 6.3e-13 48.5 0.2 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.18 OAJ29299.1 - 6.5e-14 51.6 1.4 1.6e-13 50.3 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ29299.1 - 0.00014 21.9 7.7 0.00026 21.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 OAJ29299.1 - 0.0036 17.5 12.3 0.0036 17.5 12.3 2.5 3 0 0 3 3 3 1 YL1 nuclear protein CENP-B_dimeris PF09026.10 OAJ29299.1 - 5.5 7.4 23.3 4.4 7.8 18.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rrn6 PF10214.9 OAJ29302.1 - 0.038 12.5 14.6 0.062 11.8 14.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.9 OAJ29302.1 - 0.057 12.0 3.1 0.069 11.7 3.1 1.2 1 0 0 1 1 1 0 Macoilin family Borrelia_P83 PF05262.11 OAJ29302.1 - 0.18 10.3 9.8 0.25 9.8 9.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein U79_P34 PF03064.16 OAJ29302.1 - 0.21 10.9 5.8 0.35 10.2 5.8 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 NARP1 PF12569.8 OAJ29302.1 - 0.29 10.0 11.1 0.41 9.5 11.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EPL1 PF10513.9 OAJ29302.1 - 0.65 10.4 5.4 1.4 9.2 5.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like CPSF100_C PF13299.6 OAJ29302.1 - 0.7 10.1 5.4 1.6 8.9 5.4 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MDM10 PF12519.8 OAJ29302.1 - 1.1 8.1 3.6 1.6 7.5 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Plasmodium_Vir PF05795.11 OAJ29302.1 - 1.7 7.9 5.0 0.38 10.1 1.8 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TAF4 PF05236.14 OAJ29302.1 - 2.7 7.7 16.4 0.2 11.4 9.6 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family MCM_bind PF09739.9 OAJ29302.1 - 3.4 6.0 7.2 4.7 5.5 7.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hid1 PF12722.7 OAJ29302.1 - 5.3 5.0 5.6 6.8 4.7 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.13 OAJ29302.1 - 7.1 6.5 15.4 0.35 10.7 7.6 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 OAJ29302.1 - 7.4 6.3 11.9 13 5.5 11.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EB PF01683.18 OAJ29303.1 - 5.5 7.4 56.9 3.4 8.0 8.6 5.5 3 3 2 5 5 5 0 EB module Dynamin_M PF01031.20 OAJ29304.1 - 5.7e-110 367.0 0.0 1.4e-109 365.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 OAJ29304.1 - 2.1e-56 190.6 0.0 3.6e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 OAJ29304.1 - 8e-29 99.6 0.2 5.7e-28 96.9 0.1 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 OAJ29304.1 - 0.00037 20.5 0.1 0.0018 18.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ29304.1 - 0.048 14.0 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain TipAS PF07739.13 OAJ29304.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Spt20 PF12090.8 OAJ29304.1 - 6.7 6.2 12.1 0.23 11.0 3.2 2.3 2 0 0 2 2 2 0 Spt20 family Surp PF01805.20 OAJ29306.1 - 1.2e-11 44.4 0.3 2.4e-11 43.4 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 OAJ29306.1 - 6.2e-06 25.9 0.0 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.8 OAJ29306.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 OAJ29306.1 - 0.045 14.6 0.0 0.097 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. GatB_N PF02934.15 OAJ29307.1 - 1.5e-85 286.9 0.0 1.6e-82 277.0 0.0 2.4 1 1 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 OAJ29307.1 - 1.6e-25 89.7 0.1 5.8e-14 52.2 0.0 2.5 3 0 0 3 3 3 2 GatB domain ADH_zinc_N PF00107.26 OAJ29308.1 - 1.2e-24 86.7 0.7 3.7e-24 85.2 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ29308.1 - 7.1e-16 59.5 0.0 2e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ29308.1 - 1.2e-07 31.6 0.0 1.8e-06 27.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 OAJ29308.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase UvrD_C PF13361.6 OAJ29309.1 - 5.2e-15 55.7 0.1 9.1e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAJ29309.1 - 4.7e-14 53.0 0.0 1.2e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ29309.1 - 5.5e-11 42.1 0.1 2.2e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 OAJ29309.1 - 9.2e-11 41.8 0.7 9.2e-11 41.8 0.7 3.2 4 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 OAJ29309.1 - 6e-09 35.9 0.0 0.00097 18.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 OAJ29309.1 - 2.2e-07 30.9 0.1 0.1 12.3 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase BORG_CEP PF14957.6 OAJ29309.1 - 0.088 14.0 3.2 1.1 10.5 0.2 2.7 2 0 0 2 2 2 0 Cdc42 effector DUF3754 PF12576.8 OAJ29310.1 - 0.12 12.4 2.0 0.23 11.4 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) Mito_carr PF00153.27 OAJ29311.1 - 8.8e-45 150.6 4.9 6.6e-16 58.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PMSR PF01625.21 OAJ29312.1 - 1.7e-56 190.6 0.3 2.1e-56 190.3 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase 2-Hacid_dh_C PF02826.19 OAJ29313.1 - 4.6e-36 123.9 0.0 4.3e-35 120.7 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ29313.1 - 0.00039 20.5 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh PF00389.30 OAJ29313.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PA_decarbox PF05870.11 OAJ29314.1 - 1.7e-25 89.5 0.7 1.9e-25 89.3 0.7 1.0 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) MoaF_C PF17409.2 OAJ29314.1 - 5.6e-08 32.4 0.7 7.8e-08 32.0 0.7 1.3 1 0 0 1 1 1 1 MoaF C-terminal domain MoaF PF10703.9 OAJ29314.1 - 0.0005 20.0 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 MoaF N-terminal domain Glyco_hydro_20 PF00728.22 OAJ29315.1 - 2.6e-81 273.8 0.0 3.3e-81 273.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 OAJ29315.1 - 5.4e-15 56.3 0.0 8.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 OAJ29315.1 - 0.0019 18.9 0.4 0.046 14.5 0.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Rhomboid PF01694.22 OAJ29316.1 - 5.5e-11 42.7 11.7 6.9e-05 22.9 6.3 2.6 2 1 0 2 2 2 2 Rhomboid family zf-C2H2_jaz PF12171.8 OAJ29317.1 - 2.7e-07 30.7 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ29317.1 - 4.5e-05 23.7 0.2 7.2e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 OAJ29317.1 - 0.00016 21.7 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 OAJ29317.1 - 0.062 14.2 0.1 0.12 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2203 PF09969.9 OAJ29317.1 - 0.21 12.3 4.4 0.37 11.5 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PIG-L PF02585.17 OAJ29318.1 - 9.6e-24 84.5 0.4 2.2e-23 83.3 0.4 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PPP4R2 PF09184.11 OAJ29319.1 - 0.012 15.2 4.5 0.018 14.7 4.5 1.3 1 0 0 1 1 1 0 PPP4R2 DUF3246 PF11596.8 OAJ29319.1 - 0.022 14.2 0.4 0.044 13.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NOA36 PF06524.12 OAJ29319.1 - 0.1 11.9 5.0 0.16 11.3 5.0 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ29319.1 - 0.55 9.9 8.9 0.81 9.4 8.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIE-A_C PF11521.8 OAJ29319.1 - 1.6 9.0 7.8 10 6.5 0.6 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha tRNA-synt_1 PF00133.22 OAJ29320.1 - 6.1e-69 232.8 0.1 6.9e-69 232.7 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAJ29320.1 - 8.7e-07 28.0 0.2 2.1e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) Phosducin PF02114.16 OAJ29321.1 - 7.8e-15 54.5 0.2 8.3e-07 28.2 0.0 3.3 3 0 0 3 3 3 3 Phosducin ABC2_membrane PF01061.24 OAJ29322.1 - 0.012 15.1 0.3 0.012 15.1 0.3 1.6 2 0 0 2 2 2 0 ABC-2 type transporter PDR_CDR PF06422.12 OAJ29322.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 CDR ABC transporter Ndc1_Nup PF09531.10 OAJ29324.1 - 1.8e-23 83.1 22.8 1.5e-14 53.6 4.2 4.1 3 1 0 3 3 3 2 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 OAJ29325.1 - 7e-43 146.9 57.9 1.8e-42 145.6 51.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 OAJ29325.1 - 8.5e-18 64.1 13.4 8.5e-18 64.1 13.4 1.9 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ29325.1 - 3e-14 52.7 3.8 3e-14 52.7 3.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 OAJ29325.1 - 2.9 6.1 16.9 0.0062 14.9 4.1 2.6 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4615 PF15393.6 OAJ29326.1 - 0.094 13.3 0.4 0.13 12.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) GFP PF01353.22 OAJ29326.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Green fluorescent protein SurE PF01975.17 OAJ29327.1 - 2.8e-15 56.6 0.3 2.8e-15 56.6 0.3 2.1 1 1 1 2 2 2 2 Survival protein SurE ABC1 PF03109.16 OAJ29328.1 - 6.7e-21 74.7 0.0 3.2e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family MFS_1 PF07690.16 OAJ29329.1 - 4.5e-33 114.6 37.3 7.4e-33 113.9 37.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 OAJ29329.1 - 0.0028 16.0 1.1 0.0028 16.0 1.1 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_32N PF00251.20 OAJ29330.1 - 3.9e-22 79.2 0.0 9.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 OAJ29330.1 - 9.3e-14 51.7 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 OAJ29330.1 - 0.15 12.2 1.9 1.6 9.0 0.1 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Amino_oxidase PF01593.24 OAJ29331.1 - 7.1e-60 203.6 0.1 9.2e-60 203.2 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ29331.1 - 1.3e-08 34.9 3.7 9.3e-08 32.2 3.7 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ29331.1 - 8.2e-06 25.6 5.9 0.00013 21.7 5.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ29331.1 - 0.00047 19.5 0.1 0.018 14.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ29331.1 - 0.011 14.9 1.8 0.028 13.5 1.8 1.7 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 OAJ29331.1 - 0.028 13.6 0.7 0.084 12.1 0.5 1.8 1 1 1 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAJ29331.1 - 0.031 14.8 0.1 12 6.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ29331.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 OAJ29331.1 - 0.18 11.8 0.1 0.86 9.6 0.1 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Rubredoxin PF00301.20 OAJ29333.1 - 0.0068 16.4 0.1 0.026 14.5 0.1 2.0 1 0 0 1 1 1 1 Rubredoxin RGS12_us2 PF16611.5 OAJ29333.1 - 1 9.8 10.8 2.3 8.7 4.2 2.5 2 0 0 2 2 2 0 Unstructured region between RBD and GoLoco Cytomega_UL84 PF06284.11 OAJ29334.1 - 0.063 11.7 2.1 0.1 11.1 2.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CENP-B_dimeris PF09026.10 OAJ29334.1 - 0.14 12.6 3.9 0.3 11.5 3.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Shisa PF13908.6 OAJ29334.1 - 0.95 9.7 5.2 0.25 11.6 0.5 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DNA_pol_phi PF04931.13 OAJ29334.1 - 4 5.4 5.5 5.7 4.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Utp11 PF03998.13 OAJ29335.1 - 1.7e-54 185.4 12.4 2e-54 185.1 12.4 1.1 1 0 0 1 1 1 1 Utp11 protein Syntaxin_2 PF14523.6 OAJ29335.1 - 0.12 12.8 2.0 1 9.8 0.0 2.7 3 0 0 3 3 3 0 Syntaxin-like protein SLATT_5 PF18160.1 OAJ29335.1 - 0.13 11.6 0.7 0.23 10.8 0.4 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Acyl-thio_N PF12590.8 OAJ29335.1 - 0.4 11.2 2.1 3.8 8.1 0.4 2.2 1 1 1 2 2 2 0 Acyl-ATP thioesterase Aa_trans PF01490.18 OAJ29336.1 - 7.2e-30 104.0 31.5 8.5e-30 103.8 31.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Transposase_21 PF02992.14 OAJ29338.1 - 0.039 13.2 0.1 0.087 12.1 0.1 1.6 2 0 0 2 2 2 0 Transposase family tnp2 RR_TM4-6 PF06459.12 OAJ29339.1 - 0.15 11.8 20.3 0.39 10.5 20.3 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 OAJ29339.1 - 0.19 10.5 14.6 0.31 9.8 14.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MDM10 PF12519.8 OAJ29339.1 - 1.9 7.2 14.5 3.6 6.4 14.5 1.6 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF913 PF06025.12 OAJ29339.1 - 2.5 7.0 10.6 4.9 6.0 10.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GREB1 PF15782.5 OAJ29339.1 - 4.3 4.3 21.2 6.4 3.8 21.2 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RBP_receptor PF14752.6 OAJ29339.1 - 8.2 4.9 6.6 13 4.2 6.6 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor FAM76 PF16046.5 OAJ29339.1 - 8.5 5.6 30.2 15 4.8 30.2 1.3 1 0 0 1 1 1 0 FAM76 protein Gti1_Pac2 PF09729.9 OAJ29339.1 - 9.6 6.3 18.4 33 4.5 18.4 1.9 1 0 0 1 1 1 0 Gti1/Pac2 family DEAD PF00270.29 OAJ29340.1 - 6.2e-43 146.6 0.4 9.2e-43 146.0 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29340.1 - 1.3e-27 96.3 0.6 7.9e-27 93.8 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 OAJ29340.1 - 0.00059 19.3 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 OAJ29340.1 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ29340.1 - 0.09 13.1 0.4 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 AAA domain End3 PF12761.7 OAJ29340.1 - 0.11 12.7 0.1 1.9 8.6 0.2 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Sigma70_r3 PF04539.16 OAJ29341.1 - 0.0077 16.3 0.1 3.2 7.9 0.0 4.1 3 0 0 3 3 3 1 Sigma-70 region 3 ApoLp-III PF07464.11 OAJ29341.1 - 0.04 14.0 0.1 0.04 14.0 0.1 6.5 6 2 0 6 6 6 0 Apolipophorin-III precursor (apoLp-III) DUF1283 PF06932.11 OAJ29341.1 - 0.063 13.5 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) DUF3349 PF11829.8 OAJ29341.1 - 0.26 12.1 1.1 8.1 7.3 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3349) DUF4164 PF13747.6 OAJ29341.1 - 0.29 11.5 11.8 0.074 13.3 6.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) LEA_4 PF02987.16 OAJ29341.1 - 0.31 11.2 17.2 0.056 13.5 0.9 4.6 3 0 0 3 3 3 0 Late embryogenesis abundant protein Bep_C_terminal PF17841.1 OAJ29341.1 - 3.9 7.8 10.3 9.9 6.5 0.5 5.0 4 0 0 4 4 4 0 BID domain of Bartonella effector protein (Bep) Fungal_trans PF04082.18 OAJ29342.1 - 2.9e-08 33.1 0.0 5.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ29342.1 - 8.6e-08 32.2 6.1 1.5e-07 31.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rit1_C PF17184.4 OAJ29343.1 - 6.5e-87 291.4 0.0 1.2e-86 290.6 0.0 1.4 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 OAJ29343.1 - 1.2e-10 41.6 0.0 4.2e-09 36.7 0.0 2.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain Kinesin PF00225.23 OAJ29344.1 - 9e-92 307.5 0.0 1.4e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ29344.1 - 6.9e-22 78.0 0.0 1.4e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding KLRAQ PF10205.9 OAJ29344.1 - 0.084 13.1 1.9 0.22 11.8 0.0 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein FlgN PF05130.12 OAJ29344.1 - 1.2 9.6 5.9 2.7 8.5 0.2 2.5 2 0 0 2 2 2 0 FlgN protein Cation_ATPase_C PF00689.21 OAJ29346.1 - 1.6e-44 151.8 5.3 1.6e-44 151.8 5.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 OAJ29346.1 - 2.5e-37 128.2 0.0 2.5e-37 128.2 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ29346.1 - 2.3e-21 75.7 0.4 6.4e-21 74.2 0.4 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ29346.1 - 2.2e-15 57.5 8.5 8.3e-15 55.6 8.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ29346.1 - 9.7e-10 38.0 0.1 5.6e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ29346.1 - 0.00019 21.2 1.7 0.023 14.5 0.4 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.21 OAJ29347.1 - 7.1e-17 61.5 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_transf_17 PF04724.13 OAJ29348.1 - 1.3e-124 415.8 0.0 1.6e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glycos_transf_1 PF00534.20 OAJ29349.1 - 1.6e-29 102.7 0.1 4e-28 98.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 OAJ29349.1 - 1.1e-23 84.1 0.0 2.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ29349.1 - 9.9e-23 81.0 0.0 1.8e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 OAJ29349.1 - 1.2e-12 48.6 0.0 3.6e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 OAJ29349.1 - 0.0024 18.2 0.6 2.5 8.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferases group 1 APG5 PF04106.12 OAJ29350.1 - 3e-63 213.5 0.0 3.9e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 adh_short PF00106.25 OAJ29351.1 - 2.8e-17 62.8 0.2 7.5e-16 58.2 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ29351.1 - 2e-14 53.7 0.1 1.6e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.27 OAJ29353.1 - 2.2e-28 99.3 0.0 4.1e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ29353.1 - 1.3e-18 67.0 0.4 3.1e-17 62.5 0.1 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 OAJ29353.1 - 3.6e-08 33.7 0.1 1.4e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 OAJ29353.1 - 0.009 16.7 0.1 0.029 15.1 0.1 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 OAJ29353.1 - 0.021 14.3 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family NIF3 PF01784.18 OAJ29354.1 - 5.9e-58 196.4 0.0 7.2e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) COPIIcoated_ERV PF07970.12 OAJ29355.1 - 8.2e-38 130.5 0.3 1.3e-37 129.8 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ29355.1 - 1.2e-24 86.4 0.0 2.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Mon2_C PF16206.5 OAJ29356.1 - 0.065 11.4 0.0 0.095 10.8 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein TAF4 PF05236.14 OAJ29356.1 - 4.7 6.9 27.0 12 5.6 26.8 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GRP PF07172.11 OAJ29356.1 - 8.5 7.1 17.9 0.38 11.5 11.9 1.9 2 0 0 2 2 2 0 Glycine rich protein family Cauli_VI PF01693.16 OAJ29357.1 - 7.3e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin BSD PF03909.17 OAJ29358.1 - 3.3e-16 59.0 3.6 7.3e-14 51.5 0.1 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 OAJ29358.1 - 2.1e-07 31.2 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Hamartin PF04388.12 OAJ29358.1 - 0.44 9.2 3.5 0.71 8.5 3.5 1.4 1 0 0 1 1 1 0 Hamartin protein Cauli_VI PF01693.16 OAJ29360.1 - 7e-17 61.5 0.3 1.2e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Med9 PF07544.13 OAJ29361.1 - 0.0047 17.0 2.0 0.28 11.3 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF5320 PF17253.2 OAJ29361.1 - 0.012 16.7 0.4 3.2 8.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Uds1 PF15456.6 OAJ29361.1 - 0.028 14.6 1.5 0.04 14.1 1.5 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.20 OAJ29361.1 - 0.033 14.1 0.9 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit T3SS_needle_E PF08988.10 OAJ29361.1 - 0.093 12.9 4.4 0.15 12.2 1.7 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF4479 PF14794.6 OAJ29361.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Prefoldin PF02996.17 OAJ29361.1 - 0.11 12.4 0.9 5.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit Peptidase_S15 PF02129.18 OAJ29361.1 - 0.13 11.8 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Swi5 PF07061.11 OAJ29361.1 - 0.65 10.1 3.4 20 5.3 1.2 2.2 2 0 0 2 2 2 0 Swi5 DUF4140 PF13600.6 OAJ29361.1 - 3.4 8.2 7.2 3.4e+02 1.7 7.2 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Choline_transpo PF04515.12 OAJ29362.1 - 3e-52 177.9 7.3 8.7e-52 176.3 4.5 2.6 2 1 0 2 2 2 1 Plasma-membrane choline transporter Roughex PF06020.11 OAJ29362.1 - 4.8 6.2 9.7 11 5.0 9.7 1.5 1 0 0 1 1 1 0 Drosophila roughex protein Yippee-Mis18 PF03226.14 OAJ29363.1 - 8.2e-16 58.1 0.1 9.5e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NinF PF05810.12 OAJ29363.1 - 1.4 8.9 4.4 0.65 9.9 0.2 2.4 3 0 0 3 3 3 0 NinF protein F-box PF00646.33 OAJ29364.1 - 0.003 17.4 0.0 0.0093 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ29364.1 - 0.019 14.9 0.4 0.051 13.5 0.1 1.9 2 0 0 2 2 2 0 F-box-like PI31_Prot_N PF11566.8 OAJ29365.1 - 7.2e-52 175.5 0.0 9.7e-52 175.1 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 OAJ29365.1 - 2.5e-15 57.4 18.2 2.5e-15 57.4 18.2 3.1 3 0 0 3 3 3 1 PI31 proteasome regulator MRI PF15325.6 OAJ29365.1 - 4.8 8.3 6.9 2 9.5 0.1 3.0 3 0 0 3 3 3 0 Modulator of retrovirus infection Aa_trans PF01490.18 OAJ29366.1 - 1.6e-71 241.2 18.9 2.3e-71 240.7 18.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 OAJ29366.1 - 3.1e-05 23.2 17.5 7e-05 22.0 17.5 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family SAM_1 PF00536.30 OAJ29367.1 - 0.00099 19.5 0.2 0.0024 18.3 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAJ29367.1 - 0.0091 16.1 0.1 0.021 14.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Myb_DNA-binding PF00249.31 OAJ29368.1 - 7.7e-18 64.4 3.8 1.4e-12 47.6 0.8 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ29368.1 - 3.1e-11 43.4 11.7 2.2e-08 34.2 0.3 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ29368.1 - 0.00018 21.6 0.5 0.0064 16.7 0.0 2.9 2 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 OAJ29368.1 - 0.021 15.2 11.9 0.037 14.4 0.4 3.9 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 OAJ29368.1 - 0.12 12.3 0.3 14 5.6 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain MADF_DNA_bdg PF10545.9 OAJ29368.1 - 3.7 7.9 10.6 3.1 8.2 0.1 4.1 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_7 PF15963.5 OAJ29369.1 - 2.3e-26 91.5 0.2 8.3e-26 89.7 0.2 1.9 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 OAJ29369.1 - 6.3e-07 29.5 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TOPRIM_C PF16898.5 OAJ29369.1 - 0.54 10.5 4.3 2.7 8.3 1.4 2.2 2 0 0 2 2 2 0 C-terminal associated domain of TOPRIM GST_N_3 PF13417.6 OAJ29371.1 - 2.4e-12 47.1 0.0 4.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ29371.1 - 4.5e-10 39.7 0.0 9.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ29371.1 - 0.00015 21.7 0.8 0.00024 21.0 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAJ29371.1 - 0.0057 17.4 0.0 0.041 14.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N PF02798.20 OAJ29371.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NOG1_N PF17835.1 OAJ29373.1 - 1.5e-45 155.0 0.5 2.9e-45 154.1 0.5 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 OAJ29373.1 - 6.3e-28 96.5 3.4 1.6e-27 95.3 3.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 OAJ29373.1 - 2.3e-27 94.5 0.1 4.4e-27 93.6 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 OAJ29373.1 - 2.6e-19 69.4 0.0 7.6e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ29373.1 - 1.1e-09 38.0 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ29373.1 - 0.00024 21.2 0.0 0.51 10.4 0.0 2.8 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 OAJ29373.1 - 0.0045 16.9 0.0 0.32 10.9 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase Roc PF08477.13 OAJ29373.1 - 0.033 14.4 0.0 0.2 11.9 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 OAJ29373.1 - 0.056 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 OAJ29373.1 - 0.087 13.4 0.1 1.5 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 OAJ29373.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 OAJ29373.1 - 0.12 12.8 0.0 0.39 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain RR_TM4-6 PF06459.12 OAJ29373.1 - 0.58 9.9 6.6 1.3 8.8 6.6 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_M43 PF05572.13 OAJ29374.1 - 2.3e-18 66.5 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ29374.1 - 0.0021 18.5 1.1 0.014 15.9 0.2 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ29374.1 - 0.033 14.3 2.2 0.057 13.6 2.2 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 DUF4953 PF16313.5 OAJ29374.1 - 0.085 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 OAJ29374.1 - 0.09 12.6 1.0 0.11 12.3 1.0 1.5 1 1 0 1 1 1 0 Matrixin DS PF01916.17 OAJ29374.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF4854 PF16146.5 OAJ29374.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Acetyltransf_1 PF00583.25 OAJ29375.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ29375.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YjeF_N PF03853.15 OAJ29376.1 - 3.4e-34 118.2 0.0 4.8e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus WW PF00397.26 OAJ29377.1 - 5.4e-08 32.8 6.7 3.8e-07 30.1 6.4 2.2 2 0 0 2 2 2 1 WW domain Fringe PF02434.16 OAJ29378.1 - 5.8e-09 35.8 0.4 3.4e-08 33.2 0.4 2.2 1 1 0 1 1 1 1 Fringe-like eIF-3_zeta PF05091.12 OAJ29379.1 - 2.5e-159 531.6 0.0 7.7e-159 530.0 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_60s PF00428.19 OAJ29379.1 - 5.9 7.6 17.4 29 5.3 0.1 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein Helicase_C_2 PF13307.6 OAJ29380.1 - 1.8e-54 184.5 0.0 4e-54 183.3 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 OAJ29380.1 - 7.6e-45 152.7 0.0 2.1e-44 151.3 0.0 1.8 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 OAJ29380.1 - 0.0027 17.5 0.0 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.16 OAJ29380.1 - 0.007 15.8 0.1 0.87 9.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Myc_N PF01056.18 OAJ29380.1 - 2.5 7.9 11.5 0.056 13.3 0.5 2.9 3 0 0 3 3 3 0 Myc amino-terminal region SNF2_N PF00176.23 OAJ29383.1 - 4.3e-57 193.4 0.0 3.8e-56 190.3 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ29383.1 - 2.3e-15 56.9 0.0 8.7e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ29383.1 - 1.3e-08 34.8 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 OAJ29383.1 - 2e-07 30.8 3.6 2e-07 30.8 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ29383.1 - 3.1e-06 27.2 5.6 3.1e-06 27.2 5.6 2.0 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 OAJ29383.1 - 4e-06 26.6 3.8 4e-06 26.6 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ29383.1 - 3.9e-05 23.4 4.3 3.9e-05 23.4 4.3 2.0 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 OAJ29383.1 - 4.2e-05 23.3 5.0 4.2e-05 23.3 5.0 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ29383.1 - 0.0001 22.3 1.9 0.0001 22.3 1.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ29383.1 - 0.00038 20.7 6.1 0.00038 20.7 6.1 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 OAJ29383.1 - 0.00074 19.4 5.6 0.00074 19.4 5.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ29383.1 - 0.04 13.8 4.0 0.083 12.8 4.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 OAJ29383.1 - 0.14 12.3 4.6 0.66 10.1 4.6 2.1 1 1 0 1 1 1 0 zinc RING finger of MSL2 Zn_Tnp_IS91 PF14319.6 OAJ29383.1 - 2.9 8.0 12.6 3.7 7.6 1.3 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain Ank_4 PF13637.6 OAJ29384.1 - 2.7e-08 34.2 0.0 0.00047 20.7 0.0 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ29384.1 - 3.7e-08 33.8 0.0 5.5e-07 30.1 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ29384.1 - 0.0015 18.8 0.1 5.4 7.5 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ29384.1 - 0.0018 18.7 0.0 2 9.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 OAJ29384.1 - 0.0019 18.6 0.0 20 6.2 0.0 4.8 4 1 0 4 4 4 1 Ankyrin repeat FMN_red PF03358.15 OAJ29385.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 OAJ29385.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin zf-4CXXC_R1 PF10497.9 OAJ29386.1 - 7.2e-08 32.6 10.9 1.6e-07 31.5 10.9 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 K_channel_TID PF07941.11 OAJ29386.1 - 0.016 15.7 10.3 0.016 15.7 10.3 7.8 9 1 0 9 9 9 0 Potassium channel Kv1.4 tandem inactivation domain FYVE_2 PF02318.16 OAJ29386.1 - 0.41 10.9 4.5 0.91 9.8 4.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger UPF0139 PF03669.13 OAJ29387.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Spike_torovirin PF17072.5 OAJ29387.1 - 0.05 10.8 0.0 0.06 10.5 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein DUF3446 PF11928.8 OAJ29387.1 - 0.11 12.8 0.4 0.11 12.8 0.4 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain Hid1 PF12722.7 OAJ29388.1 - 3.7e-124 415.7 0.0 3.5e-122 409.1 0.0 2.9 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 OAJ29388.1 - 1.2e-59 202.4 0.0 1.5e-58 198.7 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein SF-assemblin PF06705.11 OAJ29389.1 - 0.0047 16.3 0.2 0.0056 16.1 0.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Apolipoprotein PF01442.18 OAJ29389.1 - 0.0064 16.4 3.8 0.0097 15.8 3.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAJ29389.1 - 0.27 11.3 6.7 6.7 6.7 6.7 2.1 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4366 PF14283.6 OAJ29389.1 - 3.1 7.8 7.4 0.44 10.6 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) V-ATPase_G_2 PF16999.5 OAJ29389.1 - 3.4 8.1 14.0 9.8 6.7 1.3 2.3 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Flot PF15975.5 OAJ29389.1 - 4.3 7.5 11.5 4 7.6 0.5 2.4 2 0 0 2 2 2 0 Flotillin Tox-WTIP PF15654.6 OAJ29389.1 - 7.1 7.1 5.5 2.9 8.4 0.4 2.4 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif Mpv17_PMP22 PF04117.12 OAJ29390.1 - 8.3e-24 83.6 0.6 1.2e-23 83.0 0.6 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 OAJ29391.1 - 2.8e-08 33.7 12.6 4.5e-08 33.1 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain C5-epim_C PF06662.13 OAJ29393.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Hist_deacetyl PF00850.19 OAJ29395.1 - 5.2e-85 285.6 0.0 7.7e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 OAJ29395.1 - 1.3e-29 103.2 0.1 6.6e-12 45.1 0.0 3.1 3 0 0 3 3 3 3 Arb2 domain DnaJ PF00226.31 OAJ29396.1 - 8.3e-22 77.1 1.4 1.3e-21 76.4 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain EF_assoc_1 PF08355.12 OAJ29397.1 - 3e-05 23.5 0.0 6.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated BSP_II PF05432.11 OAJ29397.1 - 0.00049 19.9 2.0 0.00077 19.2 2.0 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) EF_assoc_2 PF08356.12 OAJ29397.1 - 0.044 13.8 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Apt1 PF10351.9 OAJ29397.1 - 0.33 9.8 5.2 0.38 9.6 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 OAJ29397.1 - 0.72 9.4 2.9 1.1 8.8 2.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4637 PF15470.6 OAJ29397.1 - 1 9.1 6.3 1.8 8.3 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Rrn6 PF10214.9 OAJ29397.1 - 1.2 7.5 13.5 1.7 7.1 13.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BUD22 PF09073.10 OAJ29397.1 - 3.1 7.1 11.5 4.3 6.6 11.5 1.2 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 OAJ29397.1 - 3.5 7.5 11.5 4.7 7.0 11.5 1.2 1 0 0 1 1 1 0 SPX domain RGS PF00615.19 OAJ29398.1 - 4.1e-36 123.8 0.1 1e-25 90.3 0.0 3.5 3 1 0 3 3 3 2 Regulator of G protein signaling domain DEP PF00610.21 OAJ29398.1 - 1.1e-13 51.0 0.1 5e-07 29.7 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Integrase_H2C2 PF17921.1 OAJ29399.1 - 4.8e-16 58.6 1.2 8.3e-16 57.9 1.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ29399.1 - 3.5e-09 36.9 0.0 6.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 OAJ29399.1 - 7.1e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 OAJ29399.1 - 0.0088 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Acid_PPase PF12689.7 OAJ29400.1 - 1.2e-49 168.4 0.0 3.4e-49 166.9 0.0 1.8 2 0 0 2 2 2 1 Acid Phosphatase RT_RNaseH PF17917.1 OAJ29400.1 - 1.7e-18 66.8 0.0 1.1e-17 64.2 0.0 2.4 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ29400.1 - 2.5e-13 50.0 0.0 4.7e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 OAJ29400.1 - 2.2e-11 43.7 0.0 1.1e-10 41.4 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVP_2 PF08284.11 OAJ29400.1 - 0.0042 16.9 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ29400.1 - 0.35 11.0 1.5 0.8 9.9 1.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DPBB_1 PF03330.18 OAJ29401.1 - 2.1e-10 40.7 0.1 4.6e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Lytic transglycolase SDA1 PF05285.12 OAJ29401.1 - 0.0094 15.4 11.5 0.012 15.0 11.5 1.1 1 0 0 1 1 1 1 SDA1 PPP4R2 PF09184.11 OAJ29401.1 - 0.02 14.5 11.9 0.031 13.9 11.9 1.3 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 OAJ29401.1 - 0.078 11.2 16.1 0.097 10.9 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 OAJ29401.1 - 0.44 9.8 21.2 0.7 9.2 21.2 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 OAJ29401.1 - 0.81 9.9 17.4 1.6 8.9 17.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 OAJ29401.1 - 0.98 7.4 23.1 1.3 7.0 23.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 OAJ29401.1 - 1 9.1 20.6 1.7 8.4 20.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 OAJ29401.1 - 2.2 6.5 9.3 2.7 6.2 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 OAJ29401.1 - 8.5 5.6 19.4 12 5.2 19.4 1.1 1 0 0 1 1 1 0 BUD22 Rer1 PF03248.13 OAJ29402.1 - 2.5e-75 251.9 0.0 3.8e-75 251.4 0.0 1.2 1 1 0 1 1 1 1 Rer1 family YL1 PF05764.13 OAJ29403.1 - 1.5 8.9 7.2 0.12 12.5 1.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein GTP_EFTU PF00009.27 OAJ29404.1 - 5.2e-19 68.5 0.0 1.5e-18 67.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 OAJ29404.1 - 1.2e-09 38.5 1.1 3.5e-09 36.9 0.7 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ29404.1 - 0.0023 18.0 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Erythro-docking PF09277.11 OAJ29404.1 - 0.037 13.9 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 Erythronolide synthase, docking PduV-EutP PF10662.9 OAJ29404.1 - 0.066 13.0 0.1 19 5.0 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CBS PF00571.28 OAJ29405.1 - 1.3e-14 54.3 8.3 0.00073 19.9 0.4 5.7 6 0 0 6 6 6 4 CBS domain SART-1 PF03343.13 OAJ29406.1 - 2.7e-139 465.6 60.9 3.3e-139 465.3 60.9 1.0 1 0 0 1 1 1 1 SART-1 family DNA_Packaging_2 PF11123.8 OAJ29406.1 - 0.034 14.3 0.2 0.1 12.8 0.2 1.8 1 0 0 1 1 1 0 DNA packaging protein Actin PF00022.19 OAJ29407.1 - 1.6e-58 198.3 0.0 4.7e-34 117.7 0.0 2.3 2 1 0 2 2 2 2 Actin DUF4677 PF15726.5 OAJ29407.1 - 0.055 13.6 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) FAD-oxidase_C PF02913.19 OAJ29407.1 - 0.069 12.8 0.8 0.11 12.1 0.3 1.5 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain Cornichon PF03311.14 OAJ29408.1 - 8.9e-53 177.8 12.8 1e-52 177.6 12.8 1.0 1 0 0 1 1 1 1 Cornichon protein MFS_1 PF07690.16 OAJ29409.1 - 2.4e-41 141.8 29.7 2.4e-41 141.8 29.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ29409.1 - 5.1e-11 42.1 3.1 5.1e-11 42.1 3.1 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ29409.1 - 1.1e-05 24.1 5.8 1.5e-05 23.6 5.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mito_carr PF00153.27 OAJ29410.1 - 1.3e-57 191.7 2.7 9.5e-22 76.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3506 PF12014.8 OAJ29411.1 - 1e-11 45.0 0.0 3.3e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 OAJ29411.1 - 9.9e-07 28.6 0.2 2.1e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ29411.1 - 2.6e-05 24.0 0.0 6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ29411.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 F-box Ribosomal_S17 PF00366.20 OAJ29412.1 - 1.8e-20 72.8 0.4 3.1e-20 72.1 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 ALO PF04030.14 OAJ29413.1 - 1.3e-56 192.3 0.1 2.6e-48 165.1 0.0 2.6 3 0 0 3 3 3 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 OAJ29413.1 - 6.3e-18 64.9 0.1 1.6e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain Ras PF00071.22 OAJ29414.1 - 1.8e-50 170.7 0.0 2.4e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ29414.1 - 1.5e-22 80.1 0.0 2.2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ29414.1 - 1.2e-05 24.8 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 OAJ29414.1 - 0.051 13.9 0.6 0.2 12.0 0.6 2.1 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 OAJ29414.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit UBA_4 PF14555.6 OAJ29415.1 - 1e-08 34.9 0.2 1.4e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 OAJ29415.1 - 0.018 14.9 8.4 0.39 10.7 1.6 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif HBM PF16591.5 OAJ29415.1 - 0.1 12.0 0.5 1.1 8.6 0.6 2.2 2 0 0 2 2 2 0 Helical bimodular sensor domain Pkinase PF00069.25 OAJ29416.1 - 7.7e-72 241.8 0.0 1e-71 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29416.1 - 3.9e-30 105.0 0.0 2.5e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 OAJ29416.1 - 3.1e-07 30.0 2.2 0.00087 18.7 0.1 3.0 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 OAJ29416.1 - 0.021 13.6 0.0 0.073 11.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 OAJ29416.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VWA_2 PF13519.6 OAJ29417.1 - 5.4e-06 27.0 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 OAJ29417.1 - 8.3e-05 22.9 0.0 0.0002 21.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Apt1 PF10351.9 OAJ29419.1 - 2.6e-117 392.6 1.0 2.6e-117 392.6 1.0 3.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 OAJ29419.1 - 4.6e-60 203.9 0.0 3.6e-59 200.9 0.0 2.2 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 OAJ29419.1 - 1.2e-44 152.2 0.0 2.3e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 OAJ29419.1 - 4.9e-38 130.5 0.0 1e-37 129.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 OAJ29419.1 - 3.4e-23 82.3 0.1 3.4e-22 79.1 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Sin3a_C PF16879.5 OAJ29420.1 - 3.9e-76 256.5 0.1 2.3e-75 254.0 0.0 2.4 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 OAJ29420.1 - 4.1e-42 142.1 8.2 7.9e-18 64.3 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 OAJ29420.1 - 4.2e-41 139.0 0.3 4.2e-41 139.0 0.3 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor Sugar_tr PF00083.24 OAJ29421.1 - 8.9e-86 288.5 20.2 1.1e-85 288.2 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29421.1 - 5.5e-16 58.4 41.2 9.6e-16 57.6 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EIIBC-GUT_N PF03612.14 OAJ29422.1 - 3.7 7.3 5.3 7.3 6.3 5.3 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4407 PF14362.6 OAJ29422.1 - 6.9 5.9 6.9 1.5 8.1 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HPHLAWLY PF14925.6 OAJ29423.1 - 0.02 13.6 9.5 0.049 12.3 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function Metallophos PF00149.28 OAJ29424.1 - 1.5e-39 136.6 0.0 2e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ29424.1 - 4e-21 75.2 0.4 8.9e-21 74.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DAO PF01266.24 OAJ29425.1 - 1.2e-21 77.7 7.2 5e-20 72.4 7.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ29425.1 - 0.0051 16.1 0.0 0.12 11.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ29425.1 - 0.017 15.7 0.0 0.033 14.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CysA_C_terminal PF17850.1 OAJ29425.1 - 0.1 13.2 0.5 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 CysA C-terminal regulatory domain CENP-T_C PF15511.6 OAJ29425.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PIG-F PF06699.11 OAJ29426.1 - 1.7e-15 57.7 10.8 5.9e-15 55.9 10.8 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF3602 PF12223.8 OAJ29427.1 - 2.3e-14 53.7 26.7 3.2e-08 34.1 4.4 4.2 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) CsgF PF10614.9 OAJ29428.1 - 1.4 9.2 4.0 0.51 10.6 0.8 1.8 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Tau95 PF09734.9 OAJ29429.1 - 1.4e-27 97.2 0.2 3e-27 96.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 OAJ29429.1 - 7.2e-15 55.3 0.1 6.5e-14 52.2 0.0 2.7 2 1 0 2 2 2 1 Tau95 Triple barrel domain RPN2_C PF18004.1 OAJ29429.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.1 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Suc_Fer-like PF06999.12 OAJ29430.1 - 4.1e-44 150.8 0.0 8.9e-44 149.7 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like MAGI_u5 PF16666.5 OAJ29430.1 - 0.0088 16.2 1.8 0.0088 16.2 1.8 1.7 1 1 0 1 1 1 1 Unstructured region on MAGI BAR_2 PF10455.9 OAJ29430.1 - 0.053 12.7 1.2 0.079 12.1 1.2 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF2347 PF09804.9 OAJ29430.1 - 0.17 11.5 1.9 0.26 10.9 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF3552 PF12072.8 OAJ29430.1 - 0.23 10.8 6.3 0.38 10.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Mannosyl_trans2 PF04188.13 OAJ29432.1 - 4e-54 184.6 5.8 5e-54 184.3 5.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) GSAP-16 PF14959.6 OAJ29432.1 - 0.011 15.6 0.2 0.02 14.8 0.2 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term LIP PF03583.14 OAJ29433.1 - 7.3e-58 196.1 0.1 9.5e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.13 OAJ29434.1 - 1.8e-19 70.4 0.0 2.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ29434.1 - 2.1e-09 36.7 0.0 0.00041 19.3 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase DUF1776 PF08643.10 OAJ29435.1 - 0.0014 18.1 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) adh_short PF00106.25 OAJ29435.1 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Spt20 PF12090.8 OAJ29435.1 - 4 7.0 21.2 1.6 8.3 9.2 2.4 2 0 0 2 2 2 0 Spt20 family Presenilin PF01080.17 OAJ29435.1 - 5.1 5.8 8.6 2.2 7.0 0.4 2.2 2 0 0 2 2 2 0 Presenilin JAB PF01398.21 OAJ29436.1 - 1.3e-32 112.3 0.1 2.5e-32 111.3 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 OAJ29436.1 - 5.4e-12 46.1 0.3 1e-11 45.2 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 OAJ29436.1 - 3.2e-06 26.9 0.0 5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 OAJ29436.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) CN_hydrolase PF00795.22 OAJ29437.1 - 2.9e-52 177.6 0.1 3.7e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PH PF00169.29 OAJ29438.1 - 2.4e-09 37.7 0.1 4.2e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 OAJ29438.1 - 0.014 15.8 0.2 0.052 14.0 0.2 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_3 PF07859.13 OAJ29439.1 - 8.6e-18 65.0 0.0 3.8e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ29439.1 - 8.3e-10 38.1 0.0 7.6e-07 28.3 0.0 2.9 2 1 0 2 2 2 2 Steryl acetyl hydrolase SprA-related PF12118.8 OAJ29439.1 - 0.56 9.3 27.7 0.14 11.3 20.8 2.5 2 0 0 2 2 2 0 SprA-related family DDHD PF02862.17 OAJ29439.1 - 1.3 9.2 11.8 1.1 9.4 6.6 2.8 2 0 0 2 2 2 0 DDHD domain TERB2 PF15101.6 OAJ29439.1 - 1.9 8.5 17.4 0.23 11.5 11.0 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 OAJ29439.1 - 4 6.8 23.6 0.23 10.8 16.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Exonuc_VII_L PF02601.15 OAJ29439.1 - 4.3 6.8 12.1 9.4 5.7 12.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit LSM PF01423.22 OAJ29440.1 - 3.6e-16 58.6 0.1 4.8e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_M3 PF01432.20 OAJ29440.1 - 0.1 11.8 0.2 0.12 11.7 0.2 1.0 1 0 0 1 1 1 0 Peptidase family M3 polyprenyl_synt PF00348.17 OAJ29441.1 - 3.1e-11 42.8 0.0 4.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase PCI PF01399.27 OAJ29442.1 - 1.5e-05 25.4 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain BCDHK_Adom3 PF10436.9 OAJ29445.1 - 5.1e-63 211.7 0.0 7e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 OAJ29445.1 - 2.3e-13 50.6 0.0 4.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ29445.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC27 PF09507.10 OAJ29446.1 - 3e-29 102.7 69.6 2.6e-17 63.4 0.0 4.5 1 1 1 3 3 3 3 DNA polymerase subunit Cdc27 AFG1_ATPase PF03969.16 OAJ29447.1 - 8.5e-87 291.4 0.0 2.3e-83 280.1 0.0 2.9 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 OAJ29447.1 - 3.1e-05 24.4 0.0 0.00017 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ29447.1 - 0.0022 18.3 0.0 0.0097 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 OAJ29447.1 - 0.04 14.3 0.0 3.1 8.2 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 OAJ29447.1 - 0.11 11.9 0.0 1.3 8.4 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 OAJ29447.1 - 0.16 11.5 0.0 0.51 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 OAJ29447.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 OAJ29449.1 - 2.3e-34 118.7 0.1 5.2e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29449.1 - 1.6e-28 99.3 0.1 2.9e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ29449.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ29449.1 - 0.26 11.5 1.0 2.1 8.6 0.3 2.6 2 1 0 2 2 2 0 AAA domain SUI1 PF01253.22 OAJ29450.1 - 3.5e-20 72.3 0.0 9.5e-20 70.9 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 OAJ29450.1 - 1.5e-10 41.6 0.5 1.5e-07 32.0 0.0 3.0 3 0 0 3 3 3 2 Pre-PUA-like domain Tub_N PF16322.5 OAJ29450.1 - 9.6 6.6 16.5 0.34 11.3 8.9 2.3 3 0 0 3 3 3 0 Tubby N-terminal GATase PF00117.28 OAJ29451.1 - 2.6e-08 33.9 0.0 2.9e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DUF3433 PF11915.8 OAJ29451.1 - 0.02 15.3 0.3 0.4 11.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Peptidase_C26 PF07722.13 OAJ29451.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C26 DEAD PF00270.29 OAJ29452.1 - 5.9e-46 156.4 0.0 2.1e-45 154.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29452.1 - 3.1e-27 95.1 0.0 3e-26 92.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ29452.1 - 0.00025 21.1 0.0 0.00071 19.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ29452.1 - 0.018 14.4 0.0 0.13 11.6 0.0 2.3 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2285 PF10074.9 OAJ29452.1 - 0.064 13.9 4.8 0.19 12.4 2.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) zf-CCHC_4 PF14392.6 OAJ29452.1 - 0.25 11.1 0.4 0.51 10.1 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 OAJ29452.1 - 0.78 9.9 2.6 1.3 9.2 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle ABATE PF07336.11 OAJ29452.1 - 2.3 8.9 6.2 10 6.8 1.3 2.5 2 0 0 2 2 2 0 Putative stress-induced transcription regulator AD PF09793.9 OAJ29453.1 - 4.7e-18 65.1 0.0 7.7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain DUF948 PF06103.11 OAJ29454.1 - 0.42 10.9 5.9 7.1 7.0 0.8 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TRAF_BIRC3_bd PF16673.5 OAJ29454.1 - 4.6 7.1 10.9 0.13 12.0 2.3 2.9 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Jacalin PF01419.17 OAJ29455.1 - 0.0006 19.7 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain H_lectin PF09458.10 OAJ29456.1 - 5.7e-07 29.6 0.0 2.1e-05 24.6 0.0 2.9 2 0 0 2 2 2 1 H-type lectin domain RNase_PH_C PF03725.15 OAJ29456.1 - 0.012 15.7 0.1 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Jacalin PF01419.17 OAJ29457.1 - 1.6e-07 31.3 0.0 0.00013 21.9 0.0 2.7 2 1 0 2 2 2 2 Jacalin-like lectin domain DUF4449 PF14613.6 OAJ29459.1 - 0.065 13.3 3.0 0.11 12.6 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4449) Glyco_hydro_130 PF04041.13 OAJ29459.1 - 0.089 11.7 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 beta-1,4-mannooligosaccharide phosphorylase RabGAP-TBC PF00566.18 OAJ29460.1 - 2.7e-15 56.6 0.0 9.8e-06 25.4 0.0 3.7 3 1 0 3 3 3 3 Rab-GTPase-TBC domain AAA_lid_8 PF17868.1 OAJ29460.1 - 0.24 11.3 0.0 0.53 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain Cofilin_ADF PF00241.20 OAJ29461.1 - 1.3e-19 70.2 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein TraX PF05857.11 OAJ29461.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 TraX protein IBR PF01485.21 OAJ29462.1 - 1.2e-20 73.4 46.8 5.1e-12 45.8 6.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 OAJ29462.1 - 0.00044 20.1 5.8 0.00044 20.1 5.8 4.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ29462.1 - 0.0067 16.7 5.3 0.0067 16.7 5.3 4.0 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ29462.1 - 0.008 16.2 2.1 0.008 16.2 2.1 4.0 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ29462.1 - 0.019 14.8 4.0 0.019 14.8 4.0 4.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf_Hakai PF18408.1 OAJ29463.1 - 0.082 12.6 2.2 4.8 7.0 0.1 2.4 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 OAJ29463.1 - 8.3 6.6 7.5 0.53 10.4 0.1 2.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain P22_portal PF16510.5 OAJ29464.1 - 1.2 7.6 29.6 0.59 8.7 10.0 2.1 2 0 0 2 2 2 0 Phage P22-like portal protein FAD_binding_3 PF01494.19 OAJ29465.1 - 2.5e-25 89.5 0.0 3.5e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ29465.1 - 1.1e-05 24.8 0.2 0.03 13.5 0.0 2.9 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ29465.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 OAJ29465.1 - 0.018 14.7 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 OAJ29465.1 - 0.03 13.4 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.27 OAJ29465.1 - 0.031 14.8 0.1 0.28 11.8 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ29465.1 - 0.071 12.3 0.2 0.34 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ29465.1 - 0.28 10.7 1.1 1.8 8.0 0.8 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ribonuc_red_lgC PF02867.15 OAJ29466.1 - 2.2e-182 607.3 0.0 2.7e-182 607.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 OAJ29466.1 - 3.2e-24 84.7 0.0 7.1e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 OAJ29466.1 - 6.4e-18 65.1 0.2 1.7e-17 63.8 0.2 1.8 1 0 0 1 1 1 1 ATP cone domain IPK PF03770.16 OAJ29467.1 - 5.8e-36 124.2 0.0 2.1e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase DcpS_C PF11969.8 OAJ29468.1 - 2e-27 95.9 0.1 3.2e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 OAJ29468.1 - 2.4e-21 76.5 0.0 3.9e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DUF5075 PF16825.5 OAJ29468.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 IGP family C-type lectin domain WD40 PF00400.32 OAJ29469.1 - 9.1e-15 54.8 0.4 1.1e-06 29.3 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29469.1 - 7.2e-05 23.0 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Mpp10 PF04006.12 OAJ29469.1 - 0.6 8.5 29.7 1.1 7.6 29.7 1.3 1 0 0 1 1 1 0 Mpp10 protein GTP_EFTU PF00009.27 OAJ29470.1 - 1e-53 181.8 0.0 1.5e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ29470.1 - 8.4e-40 135.6 0.0 1.9e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 OAJ29470.1 - 5.4e-14 52.3 0.8 5.4e-14 52.3 0.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ29470.1 - 0.00043 20.3 0.2 0.013 15.6 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 OAJ29470.1 - 0.078 12.7 0.1 14 5.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain FlpD PF02662.16 OAJ29470.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Hpt PF01627.23 OAJ29471.1 - 1.3e-09 38.2 0.1 2.6e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 Hpt domain Adeno_E1A PF02703.14 OAJ29471.1 - 0.003 17.2 0.3 0.003 17.2 0.3 1.9 1 1 1 2 2 2 1 Early E1A protein Abhydrolase_6 PF12697.7 OAJ29472.1 - 2e-13 51.5 0.2 3.4e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ29472.1 - 9.5e-08 32.0 0.1 2.3e-07 30.7 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ29472.1 - 2.7e-07 30.1 0.0 5.6e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAR PF03114.18 OAJ29473.1 - 2.8e-13 50.1 0.9 4.5e-13 49.4 0.9 1.3 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 OAJ29473.1 - 0.00019 20.7 0.2 0.00036 19.8 0.2 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 OAJ29473.1 - 0.002 17.8 0.4 0.0033 17.2 0.4 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF4349 PF14257.6 OAJ29473.1 - 0.056 12.9 3.7 0.12 11.8 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Med3 PF11593.8 OAJ29473.1 - 5.3 6.1 7.9 12 4.9 7.9 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNase_PH PF01138.21 OAJ29474.1 - 1e-22 81.1 0.0 1.5e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 EMG1 PF03587.14 OAJ29476.1 - 4.6e-77 258.1 0.0 5.8e-77 257.7 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF3498 PF12004.8 OAJ29476.1 - 0.2 10.8 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3498) Med10 PF09748.9 OAJ29477.1 - 1.3e-18 67.1 0.1 1.8e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PP2C PF00481.21 OAJ29478.1 - 1.2e-66 225.0 0.4 5.2e-51 173.8 0.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C E3_UbLigase_RBR PF18091.1 OAJ29478.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 E3 Ubiquitin Ligase RBR C-terminal domain Pap_E4 PF02711.14 OAJ29478.1 - 0.18 12.8 1.7 35 5.4 0.0 2.9 2 0 0 2 2 2 0 E4 protein Arf PF00025.21 OAJ29479.1 - 3.5e-77 257.8 0.0 4e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ29479.1 - 2.1e-15 57.0 0.0 2.8e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 OAJ29479.1 - 7.2e-13 48.5 0.0 7.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 OAJ29479.1 - 4.7e-12 45.7 0.8 1.8e-07 30.6 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ29479.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ29479.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ29479.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ29479.1 - 0.0011 18.4 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase DUF4185 PF13810.6 OAJ29479.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Methyltransf_31 PF13847.6 OAJ29480.1 - 2.2e-17 63.2 0.0 2.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ29480.1 - 6.2e-15 55.7 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ29480.1 - 3.5e-13 50.0 0.0 6.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29480.1 - 4.4e-12 46.6 0.0 6.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ29480.1 - 6.3e-10 39.1 0.0 8.6e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 OAJ29480.1 - 3.5e-06 26.9 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAJ29480.1 - 4.6e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ29480.1 - 4.6e-05 22.9 0.0 6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 OAJ29480.1 - 0.0001 22.0 0.0 0.00022 21.0 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 OAJ29480.1 - 0.00021 20.8 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 OAJ29480.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 OAJ29480.1 - 0.0091 16.0 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 OAJ29480.1 - 0.022 14.3 0.0 2.4 7.6 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain N6_Mtase PF02384.16 OAJ29480.1 - 0.025 13.8 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_9 PF08003.11 OAJ29480.1 - 0.056 12.4 0.1 0.084 11.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 OAJ29480.1 - 0.079 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Acetyltransf_5 PF13444.6 OAJ29481.1 - 0.00011 22.9 0.0 0.00054 20.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ29481.1 - 0.00017 21.5 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ29481.1 - 0.027 14.9 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ29481.1 - 0.17 12.1 0.0 1.3 9.3 0.1 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family AA_permease PF00324.21 OAJ29483.1 - 4.4e-65 220.1 31.6 5.8e-65 219.7 31.6 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 OAJ29483.1 - 5.5e-18 65.2 6.3 4.2e-09 35.9 0.0 4.3 4 0 0 4 4 4 3 Solute carrier family 12 zf-CCHC PF00098.23 OAJ29484.1 - 0.0018 18.2 5.6 0.0033 17.4 5.6 1.5 1 0 0 1 1 1 1 Zinc knuckle MFS_1 PF07690.16 OAJ29485.1 - 4.5e-37 127.8 37.2 4.5e-37 127.8 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ29485.1 - 1.4e-09 37.4 5.5 1.4e-09 37.4 5.5 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter Gar1 PF04410.14 OAJ29486.1 - 2.5e-35 121.5 0.0 3.1e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region VWA_3 PF13768.6 OAJ29487.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 OAJ29487.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain T2SS-T3SS_pil_N PF13629.6 OAJ29487.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Pilus formation protein N terminal region Gram_pos_anchor PF00746.21 OAJ29487.1 - 0.35 10.8 3.6 0.74 9.8 0.6 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Collagen PF01391.18 OAJ29488.1 - 6.3e-07 29.1 17.5 1e-06 28.4 17.5 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) YrhK PF14145.6 OAJ29488.1 - 0.045 13.6 0.5 42 4.1 0.0 3.3 3 0 0 3 3 3 0 YrhK-like protein RVT_2 PF07727.14 OAJ29489.1 - 1.3e-67 227.9 0.0 2e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ29489.1 - 6.5e-20 71.5 0.1 1.8e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ29489.1 - 2.9e-07 30.2 0.0 6.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ29489.1 - 1.9e-05 24.3 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RQC PF09382.10 OAJ29490.1 - 2e-23 82.4 0.1 5e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 OAJ29490.1 - 1.8e-19 70.2 0.0 3.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29490.1 - 1.9e-19 70.0 0.0 4.5e-18 65.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAJ29490.1 - 1.4e-17 64.2 2.8 1.4e-17 64.2 2.8 2.1 2 0 0 2 2 2 1 RecQ zinc-binding HRDC PF00570.23 OAJ29490.1 - 3.2e-11 43.1 0.0 8.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Di19_C PF14571.6 OAJ29490.1 - 0.031 14.8 0.3 1.3 9.6 1.4 3.2 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Ribosomal_S9 PF00380.19 OAJ29491.1 - 7.2e-44 149.2 0.2 1.3e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Fungal_trans PF04082.18 OAJ29492.1 - 2.4e-17 62.9 0.0 1.2e-16 60.6 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain His_Phos_2 PF00328.22 OAJ29494.1 - 1.7e-72 244.9 0.2 2.4e-72 244.4 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 OAJ29494.1 - 7.4e-35 119.0 0.1 1.5e-34 118.0 0.1 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 OAJ29494.1 - 4.5e-06 26.4 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Sterol-sensing PF12349.8 OAJ29495.1 - 1.5e-40 138.5 12.6 3.2e-40 137.4 12.6 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ29495.1 - 4.8e-12 44.8 4.0 7.2e-12 44.2 4.0 1.1 1 0 0 1 1 1 1 Patched family Abhydrolase_1 PF00561.20 OAJ29496.1 - 1.4e-34 119.9 0.1 2.4e-32 112.6 0.1 2.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAJ29496.1 - 0.0029 17.3 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Erg28 PF03694.13 OAJ29498.1 - 2.4e-44 150.2 3.5 2.9e-44 149.9 3.5 1.1 1 0 0 1 1 1 1 Erg28 like protein S1FA PF04689.13 OAJ29498.1 - 0.088 13.0 0.0 9.5 6.4 0.0 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA DHHC PF01529.20 OAJ29499.1 - 1.4e-29 102.9 9.4 1.4e-29 102.9 9.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4013 PF13197.6 OAJ29499.1 - 0.31 10.9 11.3 0.19 11.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) DUF2339 PF10101.9 OAJ29499.1 - 6.5 5.2 9.1 0.56 8.7 3.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) CagY_I PF14585.6 OAJ29500.1 - 0.068 13.3 0.3 0.22 11.6 0.3 1.9 1 0 0 1 1 1 0 CagY type 1 repeat Chorismate_bind PF00425.18 OAJ29501.1 - 1.4e-89 300.1 0.2 2.8e-89 299.1 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 OAJ29501.1 - 8.9e-25 87.6 0.0 8.1e-24 84.4 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region PRP21_like_P PF12230.8 OAJ29502.1 - 4.4e-45 154.2 3.7 4.4e-45 154.2 3.7 2.2 1 1 1 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 OAJ29502.1 - 1.6e-34 117.6 1.0 8.5e-18 64.1 0.1 2.5 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 OAJ29502.1 - 0.039 13.6 0.1 0.085 12.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-WRNIP1_ubi PF18279.1 OAJ29502.1 - 0.04 14.6 0.2 0.14 12.8 0.2 1.9 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain SAC3_GANP PF03399.16 OAJ29504.1 - 6.1e-83 278.6 0.0 1e-82 277.8 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family BRCT PF00533.26 OAJ29505.1 - 1e-25 89.9 0.0 3.5e-09 36.9 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ29505.1 - 2.3e-21 75.5 0.1 1e-09 38.2 0.0 3.9 4 0 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 OAJ29505.1 - 4.3e-08 33.4 0.0 1.2 9.6 0.0 5.3 5 0 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain TIP39 PF14980.6 OAJ29505.1 - 0.13 12.2 0.8 0.35 10.8 0.8 1.7 1 0 0 1 1 1 0 TIP39 peptide Abhydrolase_3 PF07859.13 OAJ29506.1 - 1.4e-06 28.3 1.1 2e-06 27.8 0.3 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 OAJ29506.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase COesterase PF00135.28 OAJ29506.1 - 0.23 10.3 0.0 0.84 8.4 0.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family EI24 PF07264.11 OAJ29507.1 - 3.9e-22 79.4 15.0 5.7e-22 78.8 15.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SelP_N PF04592.14 OAJ29508.1 - 1.9 7.8 8.4 2.5 7.4 8.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HsbA PF12296.8 OAJ29509.1 - 1.7e-07 31.6 4.6 2.8e-07 31.0 4.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A GAT PF03127.14 OAJ29509.1 - 0.003 17.9 0.4 0.07 13.4 0.1 2.3 2 0 0 2 2 2 1 GAT domain Cpn60_TCP1 PF00118.24 OAJ29510.1 - 2.3e-149 498.2 13.1 2.7e-149 497.9 13.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 OAJ29510.1 - 0.0002 20.9 0.2 0.00084 18.9 0.1 2.1 2 0 0 2 2 2 1 Telomere recombination SNF2_N PF00176.23 OAJ29511.1 - 3.8e-68 229.8 0.2 8.2e-68 228.7 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ29511.1 - 3.2e-21 75.8 1.2 1.5e-19 70.3 0.0 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 OAJ29511.1 - 2e-20 72.9 11.1 2e-20 72.9 11.1 2.5 2 0 0 2 2 2 1 HSA Bromodomain PF00439.25 OAJ29511.1 - 1.9e-15 56.7 0.2 4.6e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 OAJ29511.1 - 9.1e-13 48.6 1.3 9.1e-13 48.6 1.3 3.2 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 OAJ29511.1 - 8e-11 41.5 4.0 1.9e-10 40.3 4.0 1.7 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 OAJ29511.1 - 3.7e-10 40.1 0.1 1.5e-08 34.9 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit 4HBT_2 PF13279.6 OAJ29513.1 - 0.00046 20.7 0.0 0.00078 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PNP_UDP_1 PF01048.20 OAJ29514.1 - 1.5e-25 89.8 0.1 1.8e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Methyltransf_16 PF10294.9 OAJ29515.1 - 7.6e-15 55.1 0.0 1.7e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ29515.1 - 0.1 13.3 0.2 36 5.1 0.0 2.7 1 1 0 2 2 2 0 Methyltransferase domain SPO22 PF08631.10 OAJ29516.1 - 1.4e-10 41.1 0.1 1.4e-10 41.1 0.1 3.6 3 2 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 OAJ29516.1 - 1.7 9.4 6.1 5.3 7.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S8e PF01201.22 OAJ29517.1 - 7.3e-54 181.6 1.3 8.8e-54 181.4 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e TCTP PF00838.17 OAJ29518.1 - 8e-67 224.7 0.4 9e-67 224.6 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Csm1 PF12539.8 OAJ29519.1 - 8.8e-09 35.9 0.0 7.4e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 LPP PF04728.13 OAJ29519.1 - 0.21 12.0 3.5 12 6.3 0.4 3.7 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Golgin_A5 PF09787.9 OAJ29519.1 - 0.36 10.3 27.6 1.1 8.7 18.6 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 OAJ29519.1 - 0.61 9.6 18.8 1.4 8.4 8.2 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 YopE_N PF09020.10 OAJ29519.1 - 0.68 10.2 4.5 0.34 11.2 0.4 2.4 2 0 0 2 2 2 0 YopE, N terminal TSC22 PF01166.18 OAJ29519.1 - 1.4 9.2 10.2 12 6.2 0.9 3.7 4 0 0 4 4 4 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.6 OAJ29519.1 - 1.7 8.8 23.5 1.1 9.3 7.0 2.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1515 PF07439.11 OAJ29519.1 - 3.7 7.6 10.2 1.6 8.8 1.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Hamartin PF04388.12 OAJ29519.1 - 4.2 5.9 13.5 5 5.7 13.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF3138 PF11336.8 OAJ29519.1 - 5.1 5.6 5.5 3 6.4 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0242 PF06785.11 OAJ29519.1 - 8.5 6.4 19.1 2 8.5 3.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Nop52 PF05997.12 OAJ29520.1 - 3.8e-59 200.1 0.0 5.6e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Peptidase_C8 PF03569.13 OAJ29520.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase family C8 DNA_pol_phi PF04931.13 OAJ29520.1 - 0.39 8.8 5.6 0.61 8.1 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi HMG_box PF00505.19 OAJ29521.1 - 1.7e-18 66.8 6.3 6.1e-10 39.4 1.8 3.5 4 1 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ29521.1 - 8.1e-10 39.2 3.9 6e-07 30.0 0.1 3.1 3 0 0 3 3 3 2 HMG-box domain DUF3106 PF11304.8 OAJ29521.1 - 0.086 13.3 13.3 0.21 12.1 2.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) Pro_isomerase PF00160.21 OAJ29522.1 - 4.8e-37 127.7 0.0 3.9e-36 124.7 0.0 2.2 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 OAJ29522.1 - 0.057 13.9 0.1 0.057 13.9 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4604) LPP PF04728.13 OAJ29522.1 - 1.4 9.4 4.4 2.1 8.8 1.1 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Med26_C PF15693.5 OAJ29522.1 - 3.3 7.8 6.6 0.68 10.1 2.9 1.7 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal SBDS_C PF09377.10 OAJ29524.1 - 1.2e-35 122.0 0.5 1.7e-35 121.6 0.5 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 OAJ29524.1 - 7.4e-16 58.0 0.2 1.8e-15 56.8 0.1 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein 2-Hacid_dh_C PF02826.19 OAJ29524.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.32 OAJ29525.1 - 3.2e-18 65.7 2.5 1.5e-07 32.0 0.0 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.25 OAJ29525.1 - 3.9e-14 52.7 0.0 4.5e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29525.1 - 1.9e-07 30.7 0.0 0.00075 18.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT PF02985.22 OAJ29525.1 - 9.7e-06 25.4 11.6 0.054 13.8 0.5 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OAJ29525.1 - 0.00022 21.5 0.2 1.3 9.4 0.0 3.5 2 0 0 2 2 2 2 HEAT repeats Cohesin_HEAT PF12765.7 OAJ29525.1 - 0.012 15.9 1.0 0.036 14.4 0.1 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion ANAPC4_WD40 PF12894.7 OAJ29525.1 - 0.017 15.4 0.0 2.2 8.6 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 OAJ29525.1 - 0.073 13.1 0.4 12 5.9 0.1 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 OAJ29525.1 - 0.22 10.5 0.0 0.41 9.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Myb_DNA-bind_4 PF13837.6 OAJ29527.1 - 0.0076 16.6 0.2 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain KKLCAg1 PF15204.6 OAJ29527.1 - 8.4 6.6 7.2 0.95 9.6 0.5 2.6 2 1 1 3 3 3 0 Kita-kyushu lung cancer antigen 1 zf-C2H2_aberr PF17017.5 OAJ29528.1 - 0.2 11.8 1.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Aberrant zinc-finger MFS_1 PF07690.16 OAJ29529.1 - 3.8e-29 101.7 46.4 5e-27 94.8 25.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_5 PF18160.1 OAJ29529.1 - 0.68 9.2 3.4 2.3 7.5 0.4 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PfkB PF00294.24 OAJ29530.1 - 3.7e-17 62.6 0.0 1.9e-12 47.1 0.0 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Zn_clus PF00172.18 OAJ29531.1 - 4.8e-07 29.8 9.1 8.1e-07 29.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 OAJ29531.1 - 0.00043 19.4 0.4 0.013 14.5 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain CDC45 PF02724.14 OAJ29531.1 - 1.6 6.9 13.9 2.9 6.1 1.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Ribonuc_red_sm PF00268.21 OAJ29532.1 - 1e-121 405.7 1.4 1.3e-121 405.3 1.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Transposase_21 PF02992.14 OAJ29533.1 - 0.00028 20.2 0.0 0.00054 19.3 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ29533.1 - 0.00054 19.6 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RVT_2 PF07727.14 OAJ29534.1 - 8.9e-73 244.9 0.0 1.3e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ29534.1 - 1.3e-14 54.4 0.0 1.5e-13 51.0 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ29534.1 - 1.7e-05 24.6 0.0 7.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ29535.1 - 0.11 12.6 1.7 0.23 11.6 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ29535.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Got1 PF04178.12 OAJ29536.1 - 1.2e-28 99.7 19.2 1.6e-28 99.3 19.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4187 PF13821.6 OAJ29537.1 - 5.8e-17 61.2 4.4 1.3e-16 60.1 4.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Pectate_lyase_3 PF12708.7 OAJ29538.1 - 8.9e-79 264.3 10.1 1.8e-64 217.5 1.8 3.0 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAJ29538.1 - 0.0001 22.0 4.4 0.036 13.8 0.0 3.4 4 0 0 4 4 4 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 OAJ29538.1 - 0.018 14.9 3.1 0.038 13.8 1.9 2.3 2 0 0 2 2 2 0 Right handed beta helix region Sigma70_ner PF04546.13 OAJ29538.1 - 0.074 12.9 2.1 0.16 11.9 2.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 OAJ29538.1 - 1.5 8.5 5.7 2.8 7.7 5.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 OAJ29538.1 - 9.7 4.3 11.3 14 3.7 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family GST_N PF02798.20 OAJ29539.1 - 4.8e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ29539.1 - 1.3e-10 41.4 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ29539.1 - 4.2e-10 39.9 0.0 8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ29539.1 - 8.3e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 OAJ29539.1 - 5e-09 36.3 0.1 8.8e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ29539.1 - 7.6e-07 29.1 0.1 1.5e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MCM PF00493.23 OAJ29540.1 - 3.3e-101 337.1 0.0 4.9e-101 336.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ29540.1 - 6.1e-29 100.4 0.1 1e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ29540.1 - 6.4e-20 71.4 0.8 1.5e-19 70.2 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ29540.1 - 8.5e-14 52.0 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ29540.1 - 1.1e-07 31.9 0.0 2.1e-05 24.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ29540.1 - 6.9e-07 28.9 0.0 5.1e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 OAJ29540.1 - 0.0051 17.4 0.5 0.016 15.8 0.5 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 OAJ29540.1 - 0.025 14.5 0.0 0.068 13.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 OAJ29540.1 - 0.03 14.2 0.9 0.099 12.5 0.9 1.9 1 0 0 1 1 1 0 AAA lid domain PBP1_TM PF14812.6 OAJ29540.1 - 6.6 7.2 7.1 2.7 8.4 0.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hexokinase_2 PF03727.16 OAJ29541.1 - 8.3e-70 234.9 0.0 1.1e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAJ29541.1 - 2.6e-69 233.1 0.0 3.7e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Thiolase_N PF00108.23 OAJ29542.1 - 1.1e-14 54.5 0.9 1.5e-12 47.4 0.0 2.8 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ29542.1 - 1.6e-11 43.9 0.6 1.3e-10 41.0 0.3 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ29542.1 - 0.002 17.7 4.5 0.19 11.2 1.6 2.7 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ29542.1 - 0.0039 17.0 1.5 0.07 13.0 0.5 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 OAJ29542.1 - 0.017 15.1 0.7 0.11 12.5 0.7 2.4 1 1 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain DHHA1 PF02272.19 OAJ29543.1 - 1.6 9.2 7.7 4.3 7.8 7.7 1.7 1 1 0 1 1 1 0 DHHA1 domain zn-ribbon_14 PF16503.5 OAJ29544.1 - 1.5e-17 62.8 2.7 1.5e-17 62.8 2.7 3.1 4 0 0 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 OAJ29544.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 OAJ29544.1 - 0.0079 15.7 1.7 0.0079 15.7 1.7 3.0 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 OAJ29544.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DZR PF12773.7 OAJ29544.1 - 0.77 9.8 9.0 6.1 7.0 0.1 3.3 3 0 0 3 3 3 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 OAJ29544.1 - 2 8.0 10.4 0.68 9.5 0.5 3.2 3 0 0 3 3 3 0 TFIIB zinc-binding Het-C PF07217.11 OAJ29545.1 - 8.6e-211 701.3 0.0 2.3e-210 699.9 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF502 PF04367.13 OAJ29545.1 - 0.014 15.3 0.1 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF2780 PF11075.8 OAJ29545.1 - 0.036 14.2 0.5 0.87 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) DDHD PF02862.17 OAJ29546.1 - 0.055 13.6 0.3 0.092 12.9 0.3 1.4 1 0 0 1 1 1 0 DDHD domain DUF3245 PF11595.8 OAJ29546.1 - 0.23 11.9 3.5 2.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) NAD_binding_1 PF00175.21 OAJ29547.1 - 1.3e-25 90.2 0.0 2.9e-25 89.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 OAJ29547.1 - 3e-20 72.4 0.0 7e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 OAJ29547.1 - 4e-07 30.3 0.0 2.4e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 OAJ29547.1 - 0.0068 16.6 0.0 0.041 14.1 0.0 2.3 3 0 0 3 3 3 1 Siderophore-interacting FAD-binding domain DUF5336 PF17270.2 OAJ29547.1 - 0.0076 15.9 1.1 0.012 15.3 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5336) PI3_PI4_kinase PF00454.27 OAJ29548.1 - 1.6e-53 182.1 0.0 1.2e-52 179.2 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 OAJ29548.1 - 2.3e-31 108.9 1.2 2.3e-31 108.9 1.2 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 OAJ29548.1 - 1.7e-07 30.9 0.0 4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain CENP-Q PF13094.6 OAJ29548.1 - 0.33 11.1 3.8 1.6 8.9 3.8 2.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2408 PF10303.9 OAJ29550.1 - 5.3e-51 172.7 1.2 8.6e-36 123.5 0.0 4.8 4 1 1 5 5 5 4 Protein of unknown function (DUF2408) CDC45 PF02724.14 OAJ29550.1 - 0.15 10.3 0.9 0.29 9.4 0.9 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF465 PF04325.13 OAJ29550.1 - 0.7 10.0 4.6 1.6 8.8 4.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) PBP1_TM PF14812.6 OAJ29550.1 - 1.2 9.6 6.9 2.4 8.6 6.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAJ29550.1 - 6.1 4.8 9.1 11 4.0 9.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi Aminotran_1_2 PF00155.21 OAJ29551.1 - 5.5e-34 117.9 0.0 6.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II IF-2B PF01008.17 OAJ29552.1 - 7.4e-66 222.2 0.0 1e-65 221.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Methyltransf_11 PF08241.12 OAJ29553.1 - 4.2e-11 43.4 0.0 1.4e-10 41.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ29553.1 - 6.3e-10 39.1 0.0 9.7e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29553.1 - 6.6e-09 36.4 0.0 1.3e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ29553.1 - 2.4e-07 31.4 0.1 8.3e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ29553.1 - 0.0012 18.7 0.0 0.0039 17.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 OAJ29554.1 - 3.9e-06 27.1 0.0 0.0067 16.7 0.0 5.0 6 0 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ29554.1 - 0.00043 21.0 12.5 0.11 13.4 0.0 5.6 6 1 0 6 6 6 2 WD domain, G-beta repeat FAM176 PF14851.6 OAJ29554.1 - 0.15 11.7 3.2 1.8 8.2 0.8 2.7 2 0 0 2 2 2 0 FAM176 family Ge1_WD40 PF16529.5 OAJ29554.1 - 0.23 10.4 0.0 1.5 7.7 0.0 2.3 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Shugoshin_C PF07557.11 OAJ29555.1 - 2.5e-15 56.0 23.3 1.7e-10 40.4 5.3 3.9 3 0 0 3 3 3 3 Shugoshin C terminus SDA1 PF05285.12 OAJ29555.1 - 4.8 6.5 49.1 5.2 6.4 23.1 3.3 3 0 0 3 3 3 0 SDA1 BRCT_2 PF16589.5 OAJ29556.1 - 0.03 14.7 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Vac_ImportDeg PF09783.9 OAJ29557.1 - 2.2e-50 170.7 0.0 1.8e-46 157.9 0.0 2.2 2 0 0 2 2 2 2 Vacuolar import and degradation protein FAD_binding_4 PF01565.23 OAJ29558.1 - 3e-19 69.2 1.0 3e-19 69.2 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ29558.1 - 1.2e-11 44.5 0.6 3.1e-11 43.2 0.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 OAJ29558.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Slx4 PF09494.10 OAJ29559.1 - 6e-08 32.5 0.1 3.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Slx4 endonuclease Mago-bind PF09282.10 OAJ29560.1 - 9.6e-14 51.0 3.3 9.6e-14 51.0 3.3 2.0 2 0 0 2 2 2 1 Mago binding Hamartin PF04388.12 OAJ29560.1 - 0.4 9.3 5.8 0.47 9.1 5.8 1.1 1 0 0 1 1 1 0 Hamartin protein PBP1_TM PF14812.6 OAJ29560.1 - 0.45 10.9 3.5 1.2 9.6 3.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LAP1C PF05609.12 OAJ29560.1 - 2.1 7.4 6.3 2.6 7.0 6.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NOA36 PF06524.12 OAJ29560.1 - 3.5 6.9 7.1 5.4 6.2 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein SOG2 PF10428.9 OAJ29560.1 - 7.4 5.6 12.3 8.8 5.4 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ABC1 PF03109.16 OAJ29561.1 - 8e-18 64.7 0.1 1e-07 32.1 0.0 2.7 3 0 0 3 3 3 2 ABC1 family Nterm_IS4 PF13006.7 OAJ29561.1 - 0.041 14.1 0.2 0.11 12.7 0.2 1.8 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal CiPC PF15800.5 OAJ29561.1 - 0.21 11.2 2.5 0.4 10.4 2.5 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian FA_desaturase PF00487.24 OAJ29562.1 - 3.3e-25 89.4 21.8 5.7e-15 55.8 3.3 2.7 2 1 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 OAJ29562.1 - 2.2e-07 30.9 0.0 5.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CMAS PF02353.20 OAJ29563.1 - 3.8e-62 210.1 0.1 4.7e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 OAJ29563.1 - 8.8e-14 52.0 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ29563.1 - 8.5e-13 48.5 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ29563.1 - 1e-11 45.3 0.0 7e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ29563.1 - 3.2e-06 27.0 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29563.1 - 6.6e-06 26.8 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 OAJ29563.1 - 0.00018 21.1 0.0 0.00045 19.8 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 PCMT PF01135.19 OAJ29563.1 - 0.00096 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 OAJ29563.1 - 0.0052 16.9 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 OAJ29563.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 OAJ29563.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_S4e PF00900.20 OAJ29564.1 - 6.5e-35 118.9 0.1 1.4e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 OAJ29564.1 - 3e-24 84.4 0.6 6.8e-24 83.3 0.1 1.9 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 OAJ29564.1 - 8.9e-20 70.5 5.3 1.8e-19 69.5 5.3 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 OAJ29564.1 - 0.00025 20.9 1.5 0.00069 19.5 1.5 1.8 1 0 0 1 1 1 1 KOW motif S4 PF01479.25 OAJ29564.1 - 0.00045 19.9 0.2 0.00092 18.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Sipho_tail PF05709.11 OAJ29564.1 - 0.016 14.7 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Phage tail protein Chitin_synth_1 PF01644.17 OAJ29566.1 - 3.8e-71 238.3 0.0 6.3e-71 237.6 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ29566.1 - 5.4e-27 93.6 0.0 9.6e-27 92.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 OAJ29566.1 - 1.1e-23 83.7 2.5 6.7e-16 58.0 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ29566.1 - 3.8e-08 33.5 7.1 5.7e-08 32.9 0.1 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 NTP_transferase PF00483.23 OAJ29567.1 - 4.6e-05 23.1 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fes1 PF08609.10 OAJ29569.1 - 1.1e-18 67.8 0.9 1.9e-16 60.7 0.2 3.2 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 OAJ29569.1 - 7e-05 22.8 3.5 2.3 8.7 0.0 5.0 4 1 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 OAJ29569.1 - 0.012 14.2 0.0 0.89 8.0 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ29569.1 - 1.9 9.1 8.6 20 5.8 0.1 4.4 6 0 0 6 6 6 0 HEAT-like repeat PMT PF02366.18 OAJ29570.1 - 2.1e-75 253.5 12.0 4.2e-75 252.5 12.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ29570.1 - 9.9e-64 214.6 17.9 9.9e-64 214.6 17.9 2.4 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ29570.1 - 1.8e-37 129.0 0.0 5.3e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 MIR domain OppC_N PF12911.7 OAJ29570.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C YfzA PF14118.6 OAJ29571.1 - 0.35 11.3 2.7 20 5.7 0.4 2.7 2 0 0 2 2 2 0 YfzA-like protein DUF4083 PF13314.6 OAJ29571.1 - 1.6 8.7 9.2 12 6.0 0.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4083) Thioredoxin PF00085.20 OAJ29572.1 - 6.3e-26 90.4 0.0 8.3e-26 90.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ29572.1 - 1.7e-07 31.6 0.1 1e-06 29.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ29572.1 - 2.9e-06 27.5 0.0 7.1e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 OAJ29572.1 - 6.3e-06 26.3 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 OAJ29572.1 - 8.1e-05 22.4 0.3 0.016 14.9 0.1 2.1 1 1 1 2 2 2 2 Redoxin DIM1 PF02966.16 OAJ29572.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 OAJ29572.1 - 0.00023 20.6 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAJ29572.1 - 0.00026 20.9 0.1 0.00073 19.5 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 OAJ29572.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 OAJ29572.1 - 0.046 13.7 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 OAJ29572.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein zf-RING_2 PF13639.6 OAJ29573.1 - 3.2e-09 37.0 10.9 1.7e-07 31.5 1.6 3.7 3 1 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 OAJ29573.1 - 8.4e-06 25.7 0.2 0.0027 17.7 0.0 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ29573.1 - 0.00011 22.0 5.5 0.012 15.4 0.7 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ29573.1 - 0.00026 20.9 4.1 0.016 15.1 0.4 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ29573.1 - 0.00032 20.9 11.8 0.00039 20.6 2.9 2.9 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ29573.1 - 0.0039 17.2 0.8 0.0039 17.2 0.8 2.6 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ29573.1 - 0.041 13.6 6.3 7.1 6.5 0.0 3.4 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 OAJ29573.1 - 0.42 10.5 6.8 0.22 11.4 1.1 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ29573.1 - 1.4 8.6 7.5 0.21 11.2 1.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-4CXXC_R1 PF10497.9 OAJ29573.1 - 1.7 9.0 4.5 5.2 7.4 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD PF00628.29 OAJ29573.1 - 1.7 8.6 13.5 0.38 10.7 1.6 3.6 4 1 0 4 4 4 0 PHD-finger zf-RING_4 PF14570.6 OAJ29573.1 - 2.5 8.0 5.2 43 4.0 0.2 3.4 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 OAJ29573.1 - 2.7 7.9 12.0 2.6 8.0 0.9 3.3 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ29573.1 - 5.6 6.9 11.7 0.28 11.1 0.2 3.3 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 FA_hydroxylase PF04116.13 OAJ29574.1 - 1.1e-17 64.7 7.5 1.1e-17 64.7 7.5 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SPA PF08616.10 OAJ29575.1 - 0.016 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Avl9 PF09794.9 OAJ29575.1 - 0.13 10.9 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Transport protein Avl9 T2SSC PF11356.8 OAJ29575.1 - 0.58 10.1 1.9 1.4 8.8 1.9 1.7 1 0 0 1 1 1 0 Type II secretion system protein C ADH_N PF08240.12 OAJ29576.1 - 1.6e-27 95.6 3.4 2.3e-27 95.0 3.4 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L13 PF00572.18 OAJ29578.1 - 2.7e-53 179.5 1.2 3.5e-53 179.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SNARE_assoc PF09335.11 OAJ29580.1 - 5.3e-16 59.2 4.3 5.3e-16 59.2 4.3 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 OAJ29580.1 - 0.75 10.1 9.8 0.81 10.0 0.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Ras PF00071.22 OAJ29581.1 - 4.5e-36 123.9 0.1 5.1e-36 123.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ29581.1 - 3.9e-09 36.8 0.0 6.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 OAJ29581.1 - 0.0047 16.5 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 OAJ29581.1 - 0.024 14.1 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family FeoB_N PF02421.18 OAJ29581.1 - 0.082 12.4 0.0 0.098 12.2 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B Methyltransf_17 PF12692.7 OAJ29582.1 - 0.0013 18.7 0.2 0.011 15.8 0.1 2.4 2 1 1 3 3 3 1 S-adenosyl-L-methionine methyltransferase Baculo_PEP_C PF04513.12 OAJ29582.1 - 0.0058 16.7 0.4 0.74 9.9 0.1 2.8 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus PadR PF03551.14 OAJ29582.1 - 0.066 13.2 0.0 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Clp1 PF06807.14 OAJ29582.1 - 0.16 12.4 0.1 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 Tannase PF07519.11 OAJ29583.1 - 6.6e-09 35.2 0.5 1.1e-08 34.5 0.5 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Presenilin PF01080.17 OAJ29584.1 - 0.092 11.5 1.0 0.14 10.9 1.0 1.3 1 0 0 1 1 1 0 Presenilin PDGLE PF13190.6 OAJ29584.1 - 0.13 12.2 2.3 0.19 11.7 0.2 2.4 3 0 0 3 3 3 0 PDGLE domain Endomucin PF07010.12 OAJ29584.1 - 0.75 9.7 40.8 0.046 13.7 35.2 1.7 2 0 0 2 2 2 0 Endomucin SH3_9 PF14604.6 OAJ29585.1 - 6.4e-22 77.2 0.7 2e-13 50.0 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 OAJ29585.1 - 1.3e-19 69.6 0.0 2.7e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 OAJ29585.1 - 5.2e-15 54.9 0.1 1.1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 OAJ29585.1 - 2.1e-13 50.4 0.0 1.1e-12 48.1 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 OAJ29585.1 - 3.3e-12 46.1 5.1 5.2e-12 45.5 5.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 OAJ29585.1 - 0.012 15.9 0.2 0.012 15.9 0.2 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain JTB PF05439.12 OAJ29585.1 - 0.24 11.5 0.8 0.58 10.2 0.8 1.6 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) TetR_C_24 PF17932.1 OAJ29585.1 - 0.31 11.3 2.3 1.7 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MFS_1 PF07690.16 OAJ29586.1 - 2.4e-15 56.3 7.2 1.2e-06 27.7 3.2 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 OAJ29586.1 - 7.5e-07 28.1 3.6 2.3e-06 26.5 0.1 2.5 3 0 0 3 3 3 1 MFS/sugar transport protein PBP1_TM PF14812.6 OAJ29586.1 - 0.021 15.2 7.8 0.033 14.6 1.7 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1_like PF12832.7 OAJ29586.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 MFS_1 like family Plasmodium_Vir PF05795.11 OAJ29586.1 - 0.13 11.7 2.1 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Pox_A12 PF04651.13 OAJ29586.1 - 0.75 9.8 3.4 1.4 9.0 3.4 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Dicty_REP PF05086.12 OAJ29586.1 - 0.99 7.3 1.7 1.6 6.6 1.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4611 PF15387.6 OAJ29586.1 - 2.6 8.3 10.4 1.6 9.0 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 OAJ29586.1 - 3.4 8.1 18.7 2 8.8 11.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 OAJ29586.1 - 6 6.9 6.4 2.5 8.1 2.4 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal EF-hand_7 PF13499.6 OAJ29587.1 - 1.8e-12 47.6 0.1 1.7e-07 31.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ29587.1 - 2.9e-12 45.4 0.1 3e-05 23.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 OAJ29587.1 - 5.5e-11 41.2 0.0 1.3e-05 24.3 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 OAJ29587.1 - 5e-10 39.6 0.0 5.9e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 OAJ29587.1 - 5.4e-05 23.0 0.3 0.007 16.2 0.0 3.4 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 OAJ29587.1 - 0.0041 16.5 0.7 0.026 14.0 0.0 2.5 2 1 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 OAJ29587.1 - 0.083 13.8 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain ExbD PF02472.16 OAJ29587.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR PhetRS_B1 PF18262.1 OAJ29587.1 - 0.14 12.4 0.0 8.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TFIID-18kDa PF02269.16 OAJ29588.1 - 2.4e-17 62.8 0.1 3.2e-07 30.3 0.4 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit FAM75 PF14650.6 OAJ29588.1 - 0.19 11.2 6.8 0.28 10.7 6.8 1.1 1 0 0 1 1 1 0 FAM75 family RhlB PF12300.8 OAJ29588.1 - 1.8 8.6 14.7 13 5.9 12.5 2.3 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Serglycin PF04360.12 OAJ29588.1 - 8.2 6.4 6.5 2.2 8.2 3.0 1.8 2 0 0 2 2 2 0 Serglycin ThiF PF00899.21 OAJ29589.1 - 2.7e-33 115.3 0.0 6.6e-33 114.1 0.0 1.5 1 1 0 1 1 1 1 ThiF family TrkA_N PF02254.18 OAJ29589.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain GTP_cyclohydro2 PF00925.20 OAJ29590.1 - 2e-58 196.6 0.0 4.7e-58 195.4 0.0 1.6 1 1 0 1 1 1 1 GTP cyclohydrolase II zf-C3HC4_3 PF13920.6 OAJ29591.1 - 0.11 12.4 8.2 0.21 11.4 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_1 PF00561.20 OAJ29592.1 - 9.1e-14 51.7 0.0 1.9e-09 37.5 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ29592.1 - 1.3e-13 50.8 0.0 3e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ29592.1 - 5.5e-13 50.0 0.9 7.3e-13 49.6 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ29592.1 - 1.6e-10 41.0 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 OAJ29592.1 - 5.6e-09 35.1 0.0 6.4e-06 25.1 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 OAJ29592.1 - 1.8e-06 27.7 0.2 1.2e-05 25.0 0.2 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 OAJ29592.1 - 2.2e-06 27.3 0.0 2.7e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 OAJ29592.1 - 7.8e-06 26.0 0.0 1.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 OAJ29592.1 - 0.00098 18.8 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 OAJ29592.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 PAF-AH_p_II PF03403.13 OAJ29592.1 - 0.0046 15.5 0.0 1.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 OAJ29592.1 - 0.032 14.1 0.3 0.087 12.7 0.3 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1100 PF06500.11 OAJ29592.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) LIP PF03583.14 OAJ29592.1 - 0.16 11.2 0.2 0.35 10.1 0.1 1.5 1 1 1 2 2 2 0 Secretory lipase Thioredoxin PF00085.20 OAJ29594.1 - 7.7e-19 67.6 0.0 8.4e-19 67.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ29594.1 - 0.0025 18.2 0.0 0.0044 17.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 OAJ29594.1 - 0.0027 18.0 0.0 0.0088 16.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 OAJ29594.1 - 0.01 15.2 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 OAJ29594.1 - 0.028 14.4 0.0 0.037 13.9 0.0 1.3 1 1 0 1 1 1 0 AhpC/TSA family OTU PF02338.19 OAJ29595.1 - 6.4e-09 36.4 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 OAJ29595.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Menin PF05053.13 OAJ29595.1 - 0.29 9.4 0.3 0.41 9.0 0.3 1.1 1 0 0 1 1 1 0 Menin NDK PF00334.19 OAJ29596.1 - 1.7e-29 102.5 0.0 2.1e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase HemX PF04375.14 OAJ29597.1 - 0.028 13.7 25.9 0.43 9.8 10.1 2.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FUSC PF04632.12 OAJ29597.1 - 0.18 10.3 11.7 0.079 11.5 8.6 2.0 1 1 0 1 1 1 0 Fusaric acid resistance protein family Mannitol_dh PF01232.23 OAJ29597.1 - 0.78 9.9 0.0 0.78 9.9 0.0 2.5 3 1 0 3 3 3 0 Mannitol dehydrogenase Rossmann domain DUF812 PF05667.11 OAJ29597.1 - 6 5.6 41.7 0.063 12.2 5.2 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF812) COesterase PF00135.28 OAJ29598.1 - 2.7e-74 250.9 0.0 3.4e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ29598.1 - 1.9e-08 34.5 1.2 4e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Exo_endo_phos PF03372.23 OAJ29599.1 - 6.2e-15 55.3 0.0 9.2e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA PF00004.29 OAJ29600.1 - 1.6e-13 51.3 0.0 3.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ29600.1 - 1.3e-05 25.2 0.0 0.00096 19.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 OAJ29600.1 - 8.1e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 OAJ29600.1 - 0.00015 21.8 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ29600.1 - 0.00021 21.7 0.6 0.0018 18.6 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ29600.1 - 0.00023 21.4 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 OAJ29600.1 - 0.018 15.3 0.0 0.067 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 OAJ29600.1 - 0.02 15.2 0.1 0.067 13.5 0.1 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_28 PF13521.6 OAJ29600.1 - 0.024 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 OAJ29600.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ29600.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 OAJ29600.1 - 0.068 13.1 0.1 0.19 11.6 0.1 1.8 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 OAJ29600.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 OAJ29600.1 - 0.077 13.2 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ29600.1 - 0.081 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 OAJ29600.1 - 0.087 13.2 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ29600.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 OAJ29600.1 - 0.27 11.1 0.1 0.58 10.0 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Tcf25 PF04910.14 OAJ29601.1 - 1.5e-89 300.5 0.0 1.9e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TetR_C_28 PF17937.1 OAJ29601.1 - 0.017 15.6 1.1 6.9 7.2 0.2 3.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain XPC-binding PF09280.11 OAJ29601.1 - 0.23 11.2 1.3 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 XPC-binding domain YL1 PF05764.13 OAJ29601.1 - 1.3 9.1 26.7 0.48 10.5 11.6 2.4 2 0 0 2 2 2 0 YL1 nuclear protein Coilin_N PF15862.5 OAJ29601.1 - 4 7.2 5.8 11 5.8 5.8 1.7 1 0 0 1 1 1 0 Coilin N-terminus Spt20 PF12090.8 OAJ29602.1 - 2e-30 106.2 0.0 2e-30 106.2 0.0 7.4 5 3 0 5 5 5 2 Spt20 family RSN1_7TM PF02714.15 OAJ29604.1 - 2.4e-58 197.6 20.9 3.8e-58 197.0 20.9 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAJ29604.1 - 1.9e-21 76.4 0.3 1.9e-21 76.4 0.3 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAJ29604.1 - 1.7e-19 70.7 0.0 4e-10 40.2 0.0 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter DUF4611 PF15387.6 OAJ29604.1 - 9.7 6.5 10.1 1.6 9.0 2.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Tetraspanin PF00335.20 OAJ29605.1 - 4.5e-05 23.3 12.6 7.9e-05 22.5 12.6 1.4 1 1 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.15 OAJ29605.1 - 5.8 6.5 8.9 2.8 7.5 2.4 2.4 1 1 1 2 2 2 0 O-Antigen ligase Prefoldin_2 PF01920.20 OAJ29606.1 - 3.3e-18 65.6 0.5 4.7e-18 65.1 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit GlnE PF03710.15 OAJ29606.1 - 0.01 15.3 1.2 0.011 15.1 1.2 1.1 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DUF4407 PF14362.6 OAJ29606.1 - 0.4 10.0 6.5 0.49 9.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTA_holin_3TM PF11351.8 OAJ29606.1 - 2.7 8.5 5.8 0.6 10.7 2.3 1.6 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release PAC3 PF10178.9 OAJ29607.1 - 0.073 13.2 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 BUD22 PF09073.10 OAJ29607.1 - 0.15 11.4 13.1 0.2 10.9 13.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAJ29607.1 - 0.24 10.8 10.0 0.32 10.4 10.0 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 OAJ29607.1 - 0.25 9.9 8.8 0.38 9.3 8.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.9 OAJ29607.1 - 0.26 10.4 16.2 0.48 9.5 16.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAJ29607.1 - 0.31 9.1 11.9 0.39 8.8 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ29607.1 - 0.4 8.8 9.3 0.5 8.5 9.3 1.1 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 OAJ29607.1 - 1.3 6.1 3.3 1.7 5.7 3.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 OAJ29607.1 - 1.6 6.9 6.0 2 6.6 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 OAJ29607.1 - 3.1 7.1 6.7 0.19 11.1 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) EF-hand_4 PF12763.7 OAJ29608.1 - 9.5e-33 112.3 0.0 3.7e-14 52.5 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 OAJ29608.1 - 1.8e-05 25.1 0.0 0.12 12.9 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair UBA PF00627.31 OAJ29608.1 - 5.1e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HAP1_N PF04849.13 OAJ29608.1 - 0.001 18.4 0.5 0.0015 17.8 0.5 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Macoilin PF09726.9 OAJ29608.1 - 0.012 14.2 2.2 0.023 13.3 2.2 1.4 1 0 0 1 1 1 0 Macoilin family MscS_porin PF12795.7 OAJ29608.1 - 0.025 14.1 13.7 0.052 13.1 13.7 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain EF-hand_1 PF00036.32 OAJ29608.1 - 0.071 12.7 3.1 10 6.0 0.0 4.2 4 0 0 4 4 3 0 EF hand Alpha-2-MRAP_C PF06401.11 OAJ29608.1 - 0.17 11.8 1.6 0.29 11.1 1.6 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain FliJ PF02050.16 OAJ29608.1 - 0.41 10.9 6.4 0.22 11.7 2.2 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein DUF2570 PF10828.8 OAJ29608.1 - 0.6 10.0 1.7 1.3 8.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF2353 PF09789.9 OAJ29608.1 - 0.63 9.3 8.0 0.97 8.7 8.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 OAJ29608.1 - 0.76 8.6 9.2 1.4 7.7 9.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4472 PF14739.6 OAJ29608.1 - 1.4 9.7 7.2 0.37 11.5 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) GAS PF13851.6 OAJ29608.1 - 1.6 8.1 8.6 2.7 7.3 8.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1640 PF07798.11 OAJ29608.1 - 1.8 8.6 5.7 3.4 7.7 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YabA PF06156.13 OAJ29608.1 - 2.6 8.7 3.4 10 6.8 1.4 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 OAJ29608.1 - 3.1 8.2 11.5 5.1 7.5 11.5 1.3 1 0 0 1 1 1 0 Fez1 YscO PF07321.12 OAJ29608.1 - 4.3 7.3 14.4 8.5 6.3 14.4 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO Golgin_A5 PF09787.9 OAJ29608.1 - 4.7 6.6 10.0 7.6 5.9 10.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 OAJ29608.1 - 8 5.7 11.8 33 3.7 12.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 OAJ29608.1 - 8.1 3.8 10.9 12 3.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Histone PF00125.24 OAJ29609.1 - 1.7e-14 54.3 0.0 2.2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 OAJ29609.1 - 1.8e-09 37.2 0.1 2.8e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 OAJ29609.1 - 5.2e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GATase_6 PF13522.6 OAJ29610.1 - 1.3e-14 54.5 0.0 3.3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 OAJ29610.1 - 1.4e-10 41.2 0.0 2.9e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 OAJ29610.1 - 2.4e-09 36.9 0.2 4.2e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 OAJ29610.1 - 7.4e-06 25.1 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DnaJ PF00226.31 OAJ29611.1 - 1.6e-19 69.7 2.8 4.3e-19 68.4 0.3 2.9 2 1 0 2 2 2 1 DnaJ domain RSN1_7TM PF02714.15 OAJ29612.1 - 1.5e-72 244.2 22.9 2.5e-72 243.5 22.9 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 OAJ29612.1 - 1.7e-39 135.9 0.3 2.6e-39 135.3 0.3 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 OAJ29612.1 - 5.3e-36 123.7 2.1 1.7e-35 122.1 2.1 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 OAJ29612.1 - 2.9e-10 40.2 0.0 8.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Dicistro_VP4 PF11492.8 OAJ29612.1 - 0.022 14.7 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 Cyanate_lyase PF02560.14 OAJ29613.1 - 6.5e-35 118.8 0.0 1.1e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 OAJ29613.1 - 2.2e-05 24.7 0.0 3.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 OAJ29613.1 - 0.017 15.1 0.0 0.043 13.9 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix HTH_19 PF12844.7 OAJ29613.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Chitin_synth_1 PF01644.17 OAJ29614.1 - 3.2e-36 124.8 0.0 3.5e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_2 PF03142.15 OAJ29614.1 - 7.3e-12 44.7 0.0 1.3e-06 27.4 0.0 3.0 3 1 1 4 4 4 2 Chitin synthase Chitin_synth_1N PF08407.11 OAJ29614.1 - 3.7e-10 39.6 0.0 1e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Sugar_tr PF00083.24 OAJ29615.1 - 1e-121 407.0 28.7 1.2e-121 406.8 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29615.1 - 4.2e-20 72.0 46.1 7.6e-18 64.5 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1 PF00133.22 OAJ29616.1 - 1.2e-213 710.7 0.0 2.6e-212 706.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 OAJ29616.1 - 5.3e-35 120.6 0.2 1.1e-34 119.6 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 OAJ29616.1 - 7.3e-16 57.9 0.4 1.1e-08 34.3 0.2 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 OAJ29616.1 - 2.8e-07 30.2 5.8 8.7e-06 25.4 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 OAJ29616.1 - 0.00056 19.3 0.0 0.54 9.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 OAJ29616.1 - 0.12 11.3 0.3 1.5 7.6 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Aldo_ket_red PF00248.21 OAJ29617.1 - 7.5e-49 166.5 0.0 4.8e-48 163.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family ECH_1 PF00378.20 OAJ29618.1 - 1.8e-17 63.5 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ29618.1 - 5.2e-06 26.2 0.0 6.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase F-box-like PF12937.7 OAJ29619.1 - 0.019 14.8 0.3 0.05 13.5 0.1 1.9 2 0 0 2 2 2 0 F-box-like UPF0147 PF03685.13 OAJ29619.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DDOST_48kD PF03345.14 OAJ29619.1 - 0.15 10.9 2.3 0.26 10.1 2.3 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta ECH_1 PF00378.20 OAJ29620.1 - 3.9e-18 65.7 0.0 5.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ29620.1 - 0.00017 21.2 0.1 0.00023 20.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Na_Ca_ex PF01699.24 OAJ29621.1 - 3.5e-24 85.5 24.8 3.9e-14 52.8 9.7 2.7 2 1 0 2 2 2 2 Sodium/calcium exchanger protein UBN_AB PF14075.6 OAJ29622.1 - 9e-29 100.7 0.0 9e-29 100.7 0.0 3.0 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 OAJ29622.1 - 7.5e-11 41.9 0.1 7.5e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 HPC2 and ubinuclein domain DUF4207 PF13904.6 OAJ29622.1 - 0.0022 17.7 0.9 0.0022 17.7 0.9 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) FAM176 PF14851.6 OAJ29622.1 - 3.2 7.4 15.4 3.5 7.3 6.5 2.6 2 0 0 2 2 2 0 FAM176 family Pox_Ag35 PF03286.14 OAJ29622.1 - 7.3 6.3 22.0 1.9 8.3 10.6 2.8 3 0 0 3 3 3 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 OAJ29622.1 - 9.8 5.7 14.9 4.2 6.9 8.2 2.6 2 0 0 2 2 2 0 PPP4R2 MTHFR PF02219.17 OAJ29623.1 - 8.5e-94 314.1 0.0 8.8e-84 281.2 0.0 3.3 3 0 0 3 3 3 3 Methylenetetrahydrofolate reductase Cytochrom_B561 PF03188.16 OAJ29623.1 - 5.6e-09 36.3 12.3 1e-08 35.4 12.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 OAJ29623.1 - 9.8 6.3 15.8 32 4.7 15.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Roughex PF06020.11 OAJ29625.1 - 1.3 8.1 4.8 1.8 7.6 4.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 OAJ29625.1 - 7.7 5.2 8.8 11 4.7 8.8 1.2 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 OAJ29626.1 - 1.8e-28 98.5 5.5 8.2e-10 38.7 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ29626.1 - 1.4e-23 82.9 1.7 1.9e-10 40.8 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Serinc PF03348.15 OAJ29626.1 - 0.48 9.3 1.9 0.81 8.5 1.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Rap1_C PF11626.8 OAJ29626.1 - 0.62 10.2 5.8 4.9 7.3 0.0 3.7 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Clathrin_lg_ch PF01086.17 OAJ29626.1 - 1.8 8.6 15.2 1.2 9.1 1.0 3.0 3 0 0 3 3 3 0 Clathrin light chain TERB2 PF15101.6 OAJ29626.1 - 3.2 7.7 15.8 3 7.9 9.7 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Myb_DNA-binding PF00249.31 OAJ29627.1 - 6.3e-30 103.1 6.2 4.4e-10 39.6 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ29627.1 - 1.3e-24 86.2 2.0 9.5e-11 41.8 0.0 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 OAJ29627.1 - 0.0014 18.8 3.5 1 9.6 0.5 3.0 2 1 0 2 2 2 2 Rap1 Myb domain Rap1_C PF11626.8 OAJ29627.1 - 0.0092 16.1 0.1 5.4 7.2 0.0 3.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain GREB1 PF15782.5 OAJ29627.1 - 0.021 12.0 6.1 0.028 11.6 6.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MADF_DNA_bdg PF10545.9 OAJ29627.1 - 0.16 12.3 5.8 7.6 6.9 0.1 3.3 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Clathrin_lg_ch PF01086.17 OAJ29627.1 - 0.46 10.5 9.2 1.9 8.5 0.7 2.2 2 0 0 2 2 2 0 Clathrin light chain Det1 PF09737.9 OAJ29627.1 - 0.47 9.5 2.4 0.66 9.0 2.4 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 DUF572 PF04502.13 OAJ29628.1 - 2.8e-83 280.3 0.0 3.4e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) COG5 PF10392.9 OAJ29628.1 - 0.05 13.8 0.6 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 zf-ACC PF17848.1 OAJ29628.1 - 0.32 11.1 2.6 8.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Mito_carr PF00153.27 OAJ29629.1 - 2.6e-66 219.6 0.9 1.3e-22 79.6 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex14_N PF04695.13 OAJ29629.1 - 0.032 14.9 3.1 0.032 14.9 3.1 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 OAJ29629.1 - 1.4 7.6 3.1 2.3 6.9 3.1 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 OAJ29629.1 - 6.2 6.7 11.5 11 5.9 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit peroxidase PF00141.23 OAJ29630.1 - 2.8e-47 161.4 0.0 5.2e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Epiglycanin_TR PF05647.11 OAJ29630.1 - 2.6 8.0 15.7 6.4 6.8 15.7 1.7 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like SMODS PF18144.1 OAJ29631.1 - 0.043 14.0 0.0 0.056 13.6 0.0 1.3 1 1 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain SnoaL PF07366.12 OAJ29631.1 - 0.17 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PASTA PF03793.19 OAJ29633.1 - 0.086 12.7 2.5 0.1 12.5 0.6 2.1 2 0 0 2 2 2 0 PASTA domain DnaJ PF00226.31 OAJ29634.1 - 8.5e-15 54.6 2.9 9.3e-15 54.5 1.8 1.7 2 0 0 2 2 2 1 DnaJ domain DUF1279 PF06916.13 OAJ29636.1 - 1.5e-14 54.3 0.0 5.5e-14 52.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF4473 PF14747.6 OAJ29636.1 - 0.079 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) Peptidase_S8 PF00082.22 OAJ29637.1 - 7.2e-46 156.8 0.0 1.2e-45 156.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ29637.1 - 5.2e-07 30.4 0.0 8.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain Urb2 PF10441.9 OAJ29638.1 - 4.9e-40 137.7 1.7 3e-39 135.1 0.0 3.3 3 0 0 3 3 3 1 Urb2/Npa2 family TetR_C_20 PF17925.1 OAJ29638.1 - 0.0028 17.9 0.8 0.037 14.3 0.1 3.5 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain F-box-like PF12937.7 OAJ29639.1 - 2.8e-08 33.5 0.5 1.6e-07 31.1 0.8 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 OAJ29639.1 - 0.021 14.7 0.5 0.077 12.9 0.5 2.0 1 1 0 1 1 1 0 F-box domain F-box_4 PF15966.5 OAJ29639.1 - 0.13 12.1 0.1 0.9 9.4 0.0 2.5 3 0 0 3 3 3 0 F-box DMRL_synthase PF00885.19 OAJ29640.1 - 3.3e-52 176.0 0.0 4.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase BaffR-Tall_bind PF09256.10 OAJ29640.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 BAFF-R, TALL-1 binding Sld5 PF05916.11 OAJ29641.1 - 5.5e-05 23.6 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Peptidase_M17 PF00883.21 OAJ29641.1 - 0.039 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain Peptidase_M24_C PF16188.5 OAJ29641.1 - 0.039 14.0 0.2 0.57 10.3 0.0 2.4 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 Transcrip_reg PF01709.20 OAJ29642.1 - 9.5e-60 202.0 0.0 6.1e-59 199.4 0.0 1.9 1 1 0 1 1 1 1 Transcriptional regulator HTH_31 PF13560.6 OAJ29642.1 - 0.032 14.6 0.5 0.34 11.3 0.1 2.6 2 1 0 2 2 2 0 Helix-turn-helix domain Spore_III_AB PF09548.10 OAJ29642.1 - 0.053 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Adaptin_N PF01602.20 OAJ29643.1 - 8.4e-129 430.5 1.9 1e-128 430.2 1.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ29643.1 - 7.4e-62 208.2 1.6 5.8e-59 198.8 0.2 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ29643.1 - 4.7e-15 55.7 6.0 4.9e-07 30.1 0.2 4.9 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 OAJ29643.1 - 3.3e-08 33.1 5.7 0.0076 16.4 0.0 5.2 7 0 0 7 7 4 2 HEAT repeat Cnd3 PF12719.7 OAJ29643.1 - 4.9e-07 29.2 0.0 0.00057 19.2 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 OAJ29643.1 - 1.3e-06 28.2 3.0 0.0057 16.6 0.0 4.8 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ29643.1 - 4.8e-05 23.8 2.1 3.3 8.3 0.1 5.4 6 0 0 6 6 6 1 HEAT-like repeat Arm_2 PF04826.13 OAJ29643.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Armadillo-like RTP1_C1 PF10363.9 OAJ29643.1 - 0.0015 18.7 0.9 0.71 10.1 0.1 3.0 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 OAJ29643.1 - 0.027 14.9 0.3 0.56 10.6 0.0 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CLASP_N PF12348.8 OAJ29643.1 - 0.19 11.2 3.5 14 5.2 0.1 3.6 4 1 0 4 4 4 0 CLASP N terminal DUF5578 PF17741.1 OAJ29643.1 - 0.39 10.1 3.1 5.7 6.3 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5578) HAMP PF00672.25 OAJ29644.1 - 6e-37 125.8 17.8 2.3e-07 31.1 0.2 9.0 8 2 1 9 9 9 6 HAMP domain HATPase_c PF02518.26 OAJ29644.1 - 4.2e-27 94.9 0.0 1.7e-26 92.9 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 OAJ29644.1 - 2.4e-25 88.9 0.7 1.5e-24 86.3 0.5 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 OAJ29644.1 - 1.9e-16 59.8 0.5 2.6e-15 56.2 0.3 3.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain TMF_TATA_bd PF12325.8 OAJ29644.1 - 0.043 14.0 2.6 9.1 6.5 0.0 4.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3829 PF12889.7 OAJ29644.1 - 0.52 9.8 3.7 8.4 5.8 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3829) DUF3150 PF11348.8 OAJ29644.1 - 1.4 8.1 6.2 1.3 8.2 0.2 3.7 3 1 1 5 5 5 0 Protein of unknown function (DUF3150) FYRC PF05965.14 OAJ29644.1 - 1.7 8.9 3.1 90 3.3 0.0 4.2 5 0 0 5 5 5 0 F/Y rich C-terminus Rab5-bind PF09311.11 OAJ29644.1 - 3.2 7.1 14.2 2 7.7 0.2 4.7 2 2 0 3 3 3 0 Rabaptin-like protein SpoIIID PF12116.8 OAJ29644.1 - 3.8 7.7 4.7 30 4.8 0.0 4.3 6 0 0 6 6 6 0 Stage III sporulation protein D Proteasome PF00227.26 OAJ29645.1 - 6.7e-32 110.5 0.0 8.1e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit TFIID-18kDa PF02269.16 OAJ29646.1 - 7.5e-32 109.2 0.5 2.1e-30 104.6 0.7 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit NAM-associated PF14303.6 OAJ29647.1 - 1.7 9.4 17.6 0.11 13.2 11.3 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain GP67 PF17634.2 OAJ29647.1 - 1.7 9.1 14.3 4.6 7.7 14.3 1.7 1 0 0 1 1 1 0 Gene product 67 DDE_Tnp_4 PF13359.6 OAJ29648.1 - 4.3e-17 62.2 0.0 8.9e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease RyR PF02026.16 OAJ29648.1 - 0.0091 16.2 0.3 0.025 14.7 0.3 1.9 1 0 0 1 1 1 1 RyR domain DDE_Tnp_1 PF01609.21 OAJ29648.1 - 0.01 15.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Myotub-related PF06602.14 OAJ29648.1 - 0.099 11.6 0.3 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain MFS_1 PF07690.16 OAJ29649.1 - 0.00021 20.3 2.6 0.00027 20.0 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4202 PF13875.6 OAJ29650.1 - 5.3e-55 186.2 0.0 9.1e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Methyltransf_12 PF08242.12 OAJ29650.1 - 2.7e-15 56.9 0.0 2.7e-13 50.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ29650.1 - 2.2e-13 50.4 0.0 1.2e-12 48.0 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ29650.1 - 9.1e-11 42.3 0.0 5.6e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ29650.1 - 7.4e-09 36.1 0.0 4.4e-07 30.5 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ29650.1 - 1.2e-06 28.4 0.0 3.2e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ29650.1 - 0.0021 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 OAJ29650.1 - 0.017 16.2 0.1 0.11 13.5 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain ArAE_2_N PF10337.9 OAJ29651.1 - 1.9e-70 238.2 0.0 7.2e-70 236.3 0.0 1.9 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 OAJ29651.1 - 1.9e-27 96.6 0.0 5.8e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 OAJ29651.1 - 9.3e-09 35.5 18.9 9.3e-09 35.5 18.9 3.8 2 1 1 3 3 3 1 Fusaric acid resistance protein-like BSP_II PF05432.11 OAJ29651.1 - 0.066 12.9 0.5 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF5408 PF17402.2 OAJ29651.1 - 0.13 12.2 0.5 0.35 10.8 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5408) 4HBT PF03061.22 OAJ29653.1 - 1.2e-16 60.9 0.5 4e-11 43.1 0.2 2.9 2 1 1 3 3 3 2 Thioesterase superfamily SQS_PSY PF00494.19 OAJ29654.1 - 1.5e-45 155.7 6.5 7.5e-45 153.5 6.5 2.1 1 1 0 1 1 1 1 Squalene/phytoene synthase Sacchrp_dh_C PF16653.5 OAJ29655.1 - 1.7e-82 277.5 0.0 3.1e-82 276.6 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 OAJ29655.1 - 3.6e-63 212.4 0.0 7.5e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 OAJ29655.1 - 1e-23 84.0 1.8 1.1e-23 84.0 0.2 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 OAJ29655.1 - 4.1e-20 71.4 0.1 7.2e-20 70.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain NAD_binding_10 PF13460.6 OAJ29655.1 - 0.00091 19.2 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 OAJ29655.1 - 0.0023 18.4 0.2 0.0073 16.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ29655.1 - 0.0092 16.7 0.0 0.094 13.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Shikimate_DH PF01488.20 OAJ29655.1 - 0.066 13.3 0.1 0.87 9.6 0.0 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 OAJ29655.1 - 0.074 13.7 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 OAJ29655.1 - 0.089 13.5 0.2 2.5 8.9 0.1 3.0 2 1 0 2 2 2 0 Methyltransferase domain GFO_IDH_MocA PF01408.22 OAJ29655.1 - 0.2 12.5 1.1 0.34 11.8 0.1 1.9 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold WES_acyltransf PF03007.16 OAJ29658.1 - 2.5e-15 56.9 0.6 5.7e-15 55.8 0.1 1.9 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 OAJ29658.1 - 9.1e-10 38.7 0.0 1.7e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) ACPS PF01648.20 OAJ29659.1 - 3.7e-08 33.5 0.0 5.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Dehydrin PF00257.19 OAJ29659.1 - 0.018 15.6 2.6 0.031 14.8 2.6 1.4 1 0 0 1 1 1 0 Dehydrin DUF4614 PF15391.6 OAJ29659.1 - 0.069 13.1 0.5 0.1 12.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) IMUP PF15761.5 OAJ29659.1 - 4.3 8.1 13.8 1.9 9.2 10.4 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein Helicase_C_2 PF13307.6 OAJ29660.1 - 2e-13 50.8 0.0 5.6e-07 29.9 0.0 3.2 2 1 1 3 3 3 3 Helicase C-terminal domain RRM_1 PF00076.22 OAJ29661.1 - 3.3e-27 94.1 0.3 2e-16 59.6 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ29661.1 - 0.00025 21.1 0.0 0.00025 21.1 0.0 2.6 3 0 0 3 3 2 1 RNA binding motif TFIIA PF03153.13 OAJ29661.1 - 0.00041 20.5 31.6 0.00041 20.5 31.6 2.8 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Nup35_RRM_2 PF14605.6 OAJ29661.1 - 0.0026 17.7 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ29661.1 - 0.037 14.1 0.1 1.5 9.0 0.1 2.8 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 OAJ29661.1 - 0.16 11.9 0.0 0.65 9.9 0.0 2.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif LMBR1 PF04791.16 OAJ29661.1 - 2.3 7.1 3.7 3 6.6 3.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cellulose_synt PF03552.14 OAJ29661.1 - 5.5 5.4 5.3 8 4.8 5.3 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF648 PF04890.13 OAJ29661.1 - 5.6 6.6 12.8 8.9 6.0 12.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF648) SID-1_RNA_chan PF13965.6 OAJ29661.1 - 5.7 5.2 4.7 9.1 4.5 4.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 OAJ29661.1 - 7.3 4.7 44.1 0.44 8.8 27.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Cellulase PF00150.18 OAJ29662.1 - 0.034 13.6 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) He_PIG PF05345.12 OAJ29663.1 - 6e-14 52.0 11.8 2e-05 24.6 0.2 4.2 3 0 0 3 3 3 3 Putative Ig domain InPase PF18823.1 OAJ29664.1 - 0.065 12.9 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Actin PF00022.19 OAJ29666.1 - 1.8e-23 82.8 0.0 3.2e-21 75.4 0.0 3.1 4 0 0 4 4 4 2 Actin MelC1 PF06236.11 OAJ29666.1 - 0.073 13.2 5.1 0.08 13.0 2.5 2.3 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 DNA_binding_1 PF01035.20 OAJ29667.1 - 2.2e-07 30.9 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ECH_1 PF00378.20 OAJ29668.1 - 1.8e-30 106.1 0.2 1.5e-28 99.8 0.2 2.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ29668.1 - 1.4e-14 54.3 0.1 3.1e-12 46.7 0.0 2.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase CD24 PF14984.6 OAJ29669.1 - 0.16 12.2 8.0 1.5 9.1 7.7 2.8 2 0 0 2 2 2 0 CD24 protein Nse4_C PF08743.10 OAJ29670.1 - 3.5e-29 100.9 0.2 1.1e-28 99.3 0.2 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 OAJ29670.1 - 4.3e-09 36.3 1.2 9.3e-09 35.3 1.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1351 PF07083.11 OAJ29670.1 - 0.016 15.0 0.7 0.016 15.0 0.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1351) DUF3391 PF11871.8 OAJ29670.1 - 5.8 7.5 7.6 16 6.1 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Snf7 PF03357.21 OAJ29671.1 - 1.8e-46 157.9 11.5 2.1e-46 157.7 11.5 1.0 1 0 0 1 1 1 1 Snf7 Soyouz_module PF14313.6 OAJ29671.1 - 0.025 14.3 0.1 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DMPK_coil PF08826.10 OAJ29671.1 - 0.11 12.7 0.3 0.11 12.7 0.3 3.6 4 0 0 4 4 4 0 DMPK coiled coil domain like NuA4 PF09340.10 OAJ29671.1 - 0.12 12.3 4.1 0.39 10.6 1.2 2.5 2 1 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF3091 PF11291.8 OAJ29671.1 - 0.14 12.3 1.1 0.41 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) Uso1_p115_C PF04871.13 OAJ29671.1 - 0.62 10.4 16.0 1.2 9.6 11.1 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RPW8 PF05659.11 OAJ29671.1 - 0.75 9.5 6.8 11 5.7 3.3 2.8 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF5344 PF17279.2 OAJ29671.1 - 0.76 10.4 7.3 1.9 9.1 2.8 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5344) DUF848 PF05852.11 OAJ29671.1 - 1.3 9.1 10.8 1.2 9.2 8.1 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 OAJ29671.1 - 1.5 8.8 16.3 11 6.0 0.6 3.6 2 1 0 3 3 3 0 Prefoldin subunit AAA_23 PF13476.6 OAJ29671.1 - 1.7 9.1 6.0 2.3 8.7 6.0 1.2 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.12 OAJ29671.1 - 2.7 8.5 6.7 2.1 8.9 1.0 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 OAJ29671.1 - 4.7 7.7 8.5 19 5.7 0.1 3.4 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 OAJ29671.1 - 5.3 5.5 8.9 2 6.9 4.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A EMP24_GP25L PF01105.24 OAJ29671.1 - 7.7 6.4 6.9 11 5.9 0.0 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Totivirus_coat PF05518.11 OAJ29672.1 - 6.8 4.6 16.0 9.5 4.1 16.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein ADH_N PF08240.12 OAJ29673.1 - 1.7e-26 92.2 0.3 1.7e-26 92.2 0.3 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ29673.1 - 4.8e-21 75.1 0.4 9.9e-21 74.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ29673.1 - 0.0025 18.8 0.3 0.0056 17.7 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 OAJ29673.1 - 0.014 14.9 0.4 0.034 13.6 0.2 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 OAJ29673.1 - 0.016 14.7 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ACP_syn_III_C PF08541.10 OAJ29673.1 - 0.087 13.0 0.5 0.67 10.2 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_hydro_92 PF07971.12 OAJ29674.1 - 3.1e-76 257.2 0.2 3.9e-76 256.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ29674.1 - 1.2e-41 143.2 0.7 2.3e-41 142.3 0.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TFIIA PF03153.13 OAJ29675.1 - 9.1 6.1 24.8 11 5.8 9.0 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FbpC_C_terminal PF17845.1 OAJ29676.1 - 0.15 12.2 0.1 20 5.4 0.0 3.0 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain Pkinase PF00069.25 OAJ29678.1 - 2e-43 148.7 0.0 1e-40 139.8 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29678.1 - 6.5e-23 81.3 0.0 1.9e-22 79.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ29678.1 - 0.00066 19.1 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ29678.1 - 0.072 12.4 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Ecl1 PF12855.7 OAJ29679.1 - 3.1e-05 25.2 7.6 3.1e-05 25.2 7.6 7.4 2 1 3 6 6 6 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 OAJ29679.1 - 0.00041 20.4 1.5 0.0011 19.0 1.5 1.7 1 0 0 1 1 1 1 MYND finger Dicty_REP PF05086.12 OAJ29679.1 - 2.2 6.1 5.3 4 5.3 5.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol_3_Rpc31 PF11705.8 OAJ29680.1 - 0.0014 18.9 5.5 0.0014 18.9 5.5 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 OAJ29680.1 - 5.4 6.2 6.1 8.1 5.7 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein TB2_DP1_HVA22 PF03134.19 OAJ29681.1 - 5.2e-29 100.0 4.6 5.2e-29 100.0 4.6 1.4 2 0 0 2 2 2 1 TB2/DP1, HVA22 family MFS_1 PF07690.16 OAJ29682.1 - 4.2e-46 157.5 38.2 3e-45 154.7 16.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ29682.1 - 1.2e-08 34.2 8.0 1.2e-08 34.2 8.0 3.3 2 2 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 OAJ29682.1 - 1.8e-06 26.6 0.6 4.3e-06 25.3 0.6 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 OAJ29682.1 - 1.4e-05 23.7 4.4 2.8e-05 22.7 4.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 OAJ29682.1 - 0.0089 14.5 4.4 0.017 13.6 4.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF21 PF01595.20 OAJ29682.1 - 0.048 13.4 0.2 0.048 13.4 0.2 3.1 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain SQS_PSY PF00494.19 OAJ29683.1 - 1.9e-47 162.0 1.2 2.5e-47 161.6 1.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase BCIP PF13862.6 OAJ29684.1 - 1.4e-34 119.7 0.0 5.7e-34 117.7 0.0 1.8 1 1 0 1 1 1 1 p21-C-terminal region-binding protein FRQ PF09421.10 OAJ29684.1 - 0.00022 19.4 1.1 0.016 13.2 0.0 2.0 2 0 0 2 2 2 2 Frequency clock protein PGA2 PF07543.12 OAJ29684.1 - 0.87 9.6 5.1 5.2 7.1 2.0 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 PBP1_TM PF14812.6 OAJ29684.1 - 2.5 8.5 7.2 6.7 7.2 2.8 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NIF PF03031.18 OAJ29685.1 - 4.4e-53 179.2 0.1 6.2e-53 178.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 OAJ29685.1 - 0.097 13.1 0.1 0.58 10.5 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CENP-B_dimeris PF09026.10 OAJ29685.1 - 0.51 10.8 9.8 1.2 9.6 9.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 OAJ29685.1 - 5.4 5.0 15.6 8.2 4.4 15.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ29685.1 - 5.5 6.2 10.9 13 5.0 10.9 1.5 1 0 0 1 1 1 0 NOA36 protein ORC2 PF04084.14 OAJ29686.1 - 1.6e-37 129.2 0.0 7.7e-32 110.5 0.0 2.8 2 1 0 2 2 2 2 Origin recognition complex subunit 2 PBP1_TM PF14812.6 OAJ29686.1 - 0.94 9.9 16.4 4.9 7.6 0.1 5.3 5 0 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGAP PF00620.27 OAJ29687.1 - 2.3e-06 27.5 0.0 0.00011 22.1 0.0 3.2 3 1 0 3 3 3 1 RhoGAP domain FCH PF00611.23 OAJ29687.1 - 0.046 14.0 0.0 0.15 12.4 0.0 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain TPP_enzyme_N PF02776.18 OAJ29688.1 - 1.7e-52 177.5 3.4 4.7e-52 176.1 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 OAJ29688.1 - 1.4e-47 161.3 0.1 4.1e-46 156.5 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAJ29688.1 - 1.8e-40 137.8 0.3 1.8e-40 137.8 0.3 1.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain RRM_1 PF00076.22 OAJ29689.1 - 1e-34 118.2 0.0 6.5e-17 61.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med11 PF10280.9 OAJ29690.1 - 1.4e-08 35.3 1.0 2.6e-08 34.4 1.0 1.5 1 1 0 1 1 1 1 Mediator complex protein CwsA PF10814.8 OAJ29690.1 - 0.0062 16.7 2.4 0.042 14.0 0.0 2.4 2 1 0 2 2 2 1 Cell wall synthesis protein CwsA CSTF_C PF14304.6 OAJ29690.1 - 0.13 11.8 0.3 0.25 10.9 0.3 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal DUF938 PF06080.12 OAJ29691.1 - 6.6e-29 101.1 0.0 9.2e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 OAJ29691.1 - 0.019 15.7 0.1 7.1 7.4 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29691.1 - 0.019 15.7 0.1 0.087 13.6 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Scs3p PF10261.9 OAJ29692.1 - 5e-49 167.0 0.0 1.4e-48 165.6 0.0 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM YsaB PF13983.6 OAJ29692.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein RSN1_7TM PF02714.15 OAJ29693.1 - 2.4e-28 99.2 23.0 3.4e-28 98.7 23.0 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 OAJ29693.1 - 1.5e-15 57.3 2.6 1.5e-15 57.3 2.6 3.9 4 1 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 OAJ29693.1 - 8e-15 55.5 4.2 5.7e-10 39.7 0.1 3.5 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter AvrPto PF11592.8 OAJ29693.1 - 0.12 12.5 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto DHO_dh PF01180.21 OAJ29694.1 - 4.5e-91 305.1 0.0 6.4e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 OAJ29694.1 - 0.00087 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 OAJ29694.1 - 0.0018 17.4 0.5 0.027 13.5 0.2 3.0 3 1 0 3 3 3 1 FMN-dependent dehydrogenase FA_hydroxylase PF04116.13 OAJ29695.1 - 6.3e-23 81.6 20.3 6.3e-23 81.6 20.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_60s PF00428.19 OAJ29695.1 - 0.22 12.2 6.1 0.4 11.3 6.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_L2_C PF03947.18 OAJ29696.1 - 1e-45 155.0 3.0 1.4e-45 154.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Tom22 PF04281.13 OAJ29698.1 - 0.27 11.0 0.0 39 4.0 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 MFS_1 PF07690.16 OAJ29699.1 - 2.4e-40 138.5 48.3 5.3e-26 91.4 18.6 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily AMP-binding PF00501.28 OAJ29700.1 - 5.7e-48 163.5 0.0 8.1e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 OAJ29700.1 - 1.2e-11 44.4 1.0 1.6e-11 44.0 0.2 1.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 OAJ29700.1 - 0.0022 18.9 0.0 0.0048 17.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.24 OAJ29701.1 - 3.4e-34 118.5 22.1 2.6e-33 115.6 22.1 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29701.1 - 2.1e-24 86.1 33.4 2.1e-24 86.1 33.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF347 PF03988.12 OAJ29701.1 - 0.93 9.7 0.0 0.93 9.7 0.0 4.2 4 1 0 4 4 4 0 Repeat of Unknown Function (DUF347) Cutinase PF01083.22 OAJ29702.1 - 3.5e-24 85.7 0.0 4.1e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ29702.1 - 0.0057 16.2 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 OAJ29702.1 - 0.027 14.6 0.0 0.038 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_8 PF06259.12 OAJ29702.1 - 0.03 14.0 0.1 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Abhydrolase_2 PF02230.16 OAJ29702.1 - 0.053 13.3 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 OAJ29702.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Sugar_tr PF00083.24 OAJ29703.1 - 1e-32 113.6 21.0 9.5e-32 110.4 21.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ29703.1 - 2.9e-28 98.8 35.8 2.9e-28 98.8 35.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.7 OAJ29706.1 - 9.1e-08 32.6 0.1 1.5e-06 28.7 0.1 2.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ29706.1 - 2.6e-07 31.1 0.0 0.00029 21.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ29706.1 - 0.00023 21.3 0.0 25 5.9 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 OAJ29706.1 - 0.00034 20.9 0.1 2.8 8.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ29706.1 - 0.00085 19.6 0.0 3.3 8.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Glyco_hydro_18 PF00704.28 OAJ29707.1 - 8.6e-72 242.5 2.2 1.1e-71 242.2 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 OAJ29707.1 - 2.9e-09 37.2 22.8 6.2e-09 36.2 22.8 1.6 1 0 0 1 1 1 1 Chitin recognition protein HRM PF02793.22 OAJ29707.1 - 0.0023 18.2 0.2 0.0075 16.5 0.2 1.9 1 0 0 1 1 1 1 Hormone receptor domain IL13 PF03487.13 OAJ29707.1 - 0.065 13.0 0.2 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Interleukin-13 LysM PF01476.20 OAJ29708.1 - 6.3e-48 160.6 5.0 7.8e-12 45.1 0.0 6.6 6 0 0 6 6 6 6 LysM domain EF-hand_6 PF13405.6 OAJ29708.1 - 2.5e-08 33.2 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 OAJ29708.1 - 1.2e-07 30.7 0.2 0.013 15.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 OAJ29708.1 - 7e-07 28.5 1.9 0.0095 15.4 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 OAJ29708.1 - 9.1e-06 26.0 0.0 2.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 OAJ29708.1 - 0.19 11.6 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Sporozoite_P67 PF05642.11 OAJ29708.1 - 7.8 4.4 9.1 18 3.2 9.1 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen XPA_C PF05181.12 OAJ29710.1 - 3.6e-24 84.5 1.0 7.3e-24 83.5 1.0 1.6 1 0 0 1 1 1 1 XPA protein C-terminus Stc1 PF12898.7 OAJ29710.1 - 0.094 13.3 5.1 2.6 8.6 0.8 2.6 2 0 0 2 2 2 0 Stc1 domain XPA_N PF01286.18 OAJ29710.1 - 0.59 10.2 8.1 0.2 11.7 1.4 2.3 2 0 0 2 2 2 0 XPA protein N-terminal E1-E2_ATPase PF00122.20 OAJ29711.1 - 8.3e-37 126.5 13.1 6.6e-28 97.5 1.1 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ29711.1 - 3.9e-31 108.2 1.6 3.9e-31 108.2 1.6 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ29711.1 - 7.7e-18 65.5 2.2 1.8e-13 51.2 0.1 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ29711.1 - 2.5e-16 59.1 0.1 9.3e-16 57.3 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ29711.1 - 7.1e-12 45.2 0.0 1.7e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ29711.1 - 0.042 13.6 0.1 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OAJ29712.1 - 2.2e-33 115.7 0.0 3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29712.1 - 6.8e-23 81.3 0.0 9.3e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AhpC-TSA PF00578.21 OAJ29713.1 - 4.5e-32 110.6 0.0 6.2e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 OAJ29713.1 - 6.9e-13 48.5 0.0 9.3e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 OAJ29713.1 - 1.2e-10 41.1 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ACOX PF01756.19 OAJ29714.1 - 5.5e-44 149.9 0.0 9e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 OAJ29714.1 - 2.4e-19 69.3 0.0 4.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 OAJ29714.1 - 3.9e-11 43.6 0.0 1.2e-10 42.0 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 OAJ29714.1 - 7.2e-10 39.3 0.8 3.6e-09 37.0 0.8 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Endonuclease_5 PF04493.14 OAJ29715.1 - 7.3e-48 162.9 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 OAJ29715.1 - 0.048 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 TFIIA PF03153.13 OAJ29716.1 - 0.00028 21.0 5.1 0.00028 21.0 5.1 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 OAJ29716.1 - 0.019 14.4 7.3 0.038 13.4 7.3 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.26 OAJ29716.1 - 0.029 14.8 5.3 0.17 12.4 5.3 2.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type BUD22 PF09073.10 OAJ29716.1 - 0.83 8.9 17.0 1.3 8.3 17.0 1.3 1 0 0 1 1 1 0 BUD22 Radial_spoke PF04712.12 OAJ29716.1 - 6.7 5.5 12.5 10 4.9 12.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 OAJ29716.1 - 9.7 4.3 17.6 14 3.7 17.6 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_23 PF13489.6 OAJ29717.1 - 5.8e-05 23.0 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29717.1 - 0.052 14.3 0.0 0.35 11.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 OAJ29717.1 - 2.3 6.4 14.9 0.041 12.2 7.6 1.6 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 OAJ29717.1 - 5 6.4 15.6 2.5 7.4 11.2 2.2 2 0 0 2 2 2 0 SDA1 DDE_3 PF13358.6 OAJ29719.1 - 3.5e-29 101.4 0.0 5.3e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ29719.1 - 4.7e-08 32.6 0.1 7e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Winged helix-turn helix HTH_32 PF13565.6 OAJ29719.1 - 0.0059 17.2 0.4 0.0059 17.2 0.4 2.1 2 0 0 2 2 2 1 Homeodomain-like domain DDE_Tnp_ISAZ013 PF07592.11 OAJ29719.1 - 0.18 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain RT_RNaseH PF17917.1 OAJ29720.1 - 1.7e-29 102.2 0.0 4.5e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ29720.1 - 5.1e-20 71.4 0.0 1.2e-19 70.2 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ29720.1 - 1e-15 57.5 0.0 2.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain RVT_1 PF00078.27 OAJ29720.1 - 2.5e-15 56.6 0.1 4.7e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ29720.1 - 3.5e-11 43.3 0.0 8.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVP_2 PF08284.11 OAJ29720.1 - 1.4e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.23 OAJ29720.1 - 0.00012 22.0 1.6 0.00022 21.1 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 OAJ29720.1 - 0.00054 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 OAJ29720.1 - 0.00056 20.4 0.0 0.0019 18.7 0.0 1.9 2 0 0 2 2 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 OAJ29720.1 - 0.0008 19.3 0.1 0.0023 17.8 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 OAJ29720.1 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger zf-CCHC_6 PF15288.6 OAJ29720.1 - 0.013 15.3 0.8 0.047 13.5 0.8 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 OAJ29720.1 - 0.021 14.8 0.1 0.052 13.5 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle Retrotrans_gag PF03732.17 OAJ29720.1 - 0.089 13.1 0.2 0.43 10.9 0.0 2.3 2 0 0 2 2 1 0 Retrotransposon gag protein zf-CCHC_2 PF13696.6 OAJ29720.1 - 0.12 12.2 2.1 0.24 11.3 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle PseudoU_synth_1 PF01416.20 OAJ29721.1 - 2.6e-13 50.3 0.0 9.5e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase FAM176 PF14851.6 OAJ29721.1 - 0.29 10.8 1.9 0.59 9.8 1.9 1.4 1 0 0 1 1 1 0 FAM176 family GST_N_3 PF13417.6 OAJ29722.1 - 1.1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ29722.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NDC10_II PF16787.5 OAJ29723.1 - 3.2e-44 151.3 0.0 5.1e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ29723.1 - 5.7e-10 39.4 0.0 2e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes F-box PF00646.33 OAJ29724.1 - 0.097 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 OAJ29725.1 - 0.66 9.9 4.0 2.1 8.3 0.8 2.7 2 0 0 2 2 2 0 F-box-like DUF3584 PF12128.8 OAJ29726.1 - 9e-05 20.2 0.6 0.0001 20.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF883 PF05957.13 OAJ29726.1 - 0.0017 18.9 6.3 0.0017 18.9 6.3 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF4337 PF14235.6 OAJ29726.1 - 0.0032 17.6 0.9 0.0051 16.9 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) FPN1 PF06963.12 OAJ29726.1 - 0.012 14.2 0.2 0.014 14.0 0.2 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RRF PF01765.19 OAJ29726.1 - 0.014 15.4 4.6 0.02 14.9 4.6 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Borrelia_P83 PF05262.11 OAJ29726.1 - 0.02 13.4 3.1 0.023 13.2 3.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Jnk-SapK_ap_N PF09744.9 OAJ29726.1 - 0.023 14.9 5.9 0.031 14.5 5.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 OAJ29726.1 - 0.06 13.8 4.8 0.082 13.3 4.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RR_TM4-6 PF06459.12 OAJ29726.1 - 0.15 11.9 4.3 0.18 11.6 4.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMPIT PF07851.13 OAJ29726.1 - 0.15 11.2 1.0 0.19 11.0 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3810 PF12725.7 OAJ29726.1 - 0.23 10.8 0.7 0.3 10.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_S49_N PF08496.10 OAJ29726.1 - 0.32 11.1 5.0 0.52 10.4 5.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_B PF00430.18 OAJ29726.1 - 0.53 10.4 10.6 0.95 9.6 10.6 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Prominin PF05478.11 OAJ29726.1 - 0.86 7.5 2.0 1.1 7.2 2.0 1.0 1 0 0 1 1 1 0 Prominin DUF4366 PF14283.6 OAJ29726.1 - 0.9 9.6 5.5 0.087 12.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 OAJ29726.1 - 1.4 7.7 2.8 1.7 7.3 2.8 1.2 1 0 0 1 1 1 0 Presenilin LCD1 PF09798.9 OAJ29726.1 - 4.7 5.6 6.9 6.2 5.2 6.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Phasin PF05597.11 OAJ29726.1 - 4.8 7.2 12.7 30 4.6 4.0 3.1 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ax_dynein_light PF10211.9 OAJ29726.1 - 5.8 6.8 10.0 8 6.4 10.0 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain XhlA PF10779.9 OAJ29726.1 - 8.4 6.7 7.2 4.8 7.5 4.7 1.9 1 1 1 2 2 2 0 Haemolysin XhlA Leu_leader PF08054.11 OAJ29727.1 - 0.0063 16.1 0.8 0.017 14.7 0.8 1.7 1 0 0 1 1 1 1 Leucine operon leader peptide Zw10 PF06248.13 OAJ29727.1 - 0.032 12.8 0.9 0.55 8.7 0.0 2.6 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 PUF PF00806.19 OAJ29728.1 - 2.9e-11 42.4 0.0 0.02 14.6 0.0 5.9 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat Adaptin_binding PF10199.9 OAJ29728.1 - 0.45 11.1 22.9 2 9.0 0.4 4.3 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 Bot1p PF12298.8 OAJ29729.1 - 3.9e-23 82.5 0.0 3.9e-23 82.5 0.0 1.9 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 OAJ29729.1 - 0.05 13.8 0.0 0.05 13.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 Macoilin PF09726.9 OAJ29729.1 - 0.37 9.3 9.4 0.0048 15.5 1.0 1.9 2 0 0 2 2 2 0 Macoilin family TPR_2 PF07719.17 OAJ29730.1 - 2.4e-25 86.6 18.0 0.00037 20.4 0.2 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ29730.1 - 6.1e-23 79.6 12.9 0.0047 16.7 0.1 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat DnaJ PF00226.31 OAJ29730.1 - 2.9e-21 75.3 1.6 6.6e-21 74.2 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 OAJ29730.1 - 2.1e-17 63.4 20.9 0.00044 20.7 7.2 6.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ29730.1 - 5.1e-16 59.0 23.8 0.00011 22.7 1.1 6.5 4 3 2 7 7 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ29730.1 - 5.7e-15 55.4 16.7 1.3e-05 25.4 0.1 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ29730.1 - 7.9e-14 51.2 21.3 0.031 15.1 0.1 6.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ29730.1 - 7.1e-13 47.7 16.2 0.019 15.2 0.1 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ29730.1 - 6e-11 42.4 9.8 0.019 15.2 1.3 4.4 2 2 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ29730.1 - 3.5e-09 36.7 8.0 0.0078 16.3 0.4 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ29730.1 - 2.6e-07 30.2 4.2 0.31 11.2 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ29730.1 - 9.1e-07 28.5 23.0 0.0011 18.7 1.8 6.5 5 2 2 7 7 7 2 TPR repeat TPR_17 PF13431.6 OAJ29730.1 - 4.7e-06 26.6 7.5 1 9.9 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ29730.1 - 1.9e-05 24.2 8.6 0.0086 15.5 0.8 3.4 1 1 1 3 3 3 2 MalT-like TPR region Fis1_TPR_C PF14853.6 OAJ29730.1 - 6.1e-05 23.0 10.6 0.0092 16.0 0.2 4.9 4 1 1 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 OAJ29730.1 - 0.00013 22.4 19.8 0.5 11.1 0.0 7.3 7 0 0 7 7 6 1 Tetratricopeptide repeat DUF1840 PF08895.11 OAJ29730.1 - 0.012 15.9 6.8 0.082 13.2 1.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) TPR_4 PF07721.14 OAJ29730.1 - 0.021 15.4 4.6 0.48 11.2 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GATase1_like PF07090.11 OAJ29730.1 - 0.068 12.6 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative glutamine amidotransferase SMBP PF16785.5 OAJ29730.1 - 0.078 13.2 13.6 0.27 11.5 1.6 4.6 4 1 1 5 5 5 0 Small metal-binding protein PTN_MK_C PF01091.18 OAJ29730.1 - 0.21 12.0 1.8 0.33 11.4 0.2 2.1 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain TPM_phosphatase PF04536.14 OAJ29730.1 - 0.23 11.7 3.6 51 4.0 0.0 3.6 2 1 1 3 3 3 0 TPM domain DUF3856 PF12968.7 OAJ29730.1 - 0.26 11.3 4.1 2.3 8.3 0.3 3.2 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 OAJ29730.1 - 1.2 9.3 4.1 23 5.2 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 OAJ29730.1 - 1.6 8.9 17.4 7.3 6.7 0.1 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ICL PF00463.21 OAJ29731.1 - 4.1e-158 527.1 0.0 4.7e-158 526.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAJ29731.1 - 3.1e-09 36.7 0.0 5.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAJ29731.1 - 0.018 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain PSA_CBD PF18341.1 OAJ29731.1 - 0.061 13.4 0.0 0.33 11.0 0.0 2.1 2 0 0 2 2 2 0 PSA endolysin C-terminal cell wall binding domain Peptidase_M48_N PF16491.5 OAJ29731.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Rad9 PF04139.13 OAJ29732.1 - 5.5e-38 130.8 0.0 1.9e-37 129.1 0.0 1.8 1 1 0 1 1 1 1 Rad9 DUF953 PF06110.11 OAJ29732.1 - 6.2e-17 61.3 0.0 1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 OAJ29732.1 - 0.0042 17.1 0.0 0.061 13.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin MAPEG PF01124.18 OAJ29733.1 - 1.6e-09 37.8 6.4 3.6e-09 36.6 6.4 1.8 1 1 0 1 1 1 1 MAPEG family Gram_pos_anchor PF00746.21 OAJ29733.1 - 4 7.5 8.6 7.9 6.5 0.6 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DEAD_2 PF06733.15 OAJ29734.1 - 1.8e-49 167.8 0.2 1.3e-43 148.7 0.0 2.5 3 0 0 3 3 3 2 DEAD_2 Helicase_C_2 PF13307.6 OAJ29734.1 - 2e-44 151.8 0.0 4.2e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 OAJ29734.1 - 1.2e-42 145.8 0.9 4.4e-39 134.1 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 OAJ29734.1 - 0.00035 20.6 0.0 0.021 14.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 OAJ29734.1 - 0.021 14.6 0.0 2.8 7.7 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ29734.1 - 0.042 14.1 0.1 8 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain Phyto-Amp PF15438.6 OAJ29735.1 - 0.043 13.6 2.4 0.29 11.0 0.4 2.1 1 1 1 2 2 2 0 Antigenic membrane protein of phytoplasma PTR PF12789.7 OAJ29735.1 - 0.049 13.7 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Phage tail repeat like ABC_tran PF00005.27 OAJ29736.1 - 5.7e-45 153.2 0.1 3.2e-22 79.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 OAJ29736.1 - 3e-20 73.3 0.1 0.0003 20.7 0.0 4.4 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 OAJ29736.1 - 6.7e-15 55.1 1.6 0.011 15.2 0.1 4.3 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ29736.1 - 3.6e-09 36.2 0.4 0.0031 17.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ29736.1 - 5e-06 27.1 7.0 0.014 15.9 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 OAJ29736.1 - 6.5e-06 26.5 0.0 0.7 10.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAJ29736.1 - 2e-05 25.1 0.1 0.19 12.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ29736.1 - 3.3e-05 23.9 0.0 0.055 13.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ29736.1 - 5.1e-05 23.3 0.0 0.34 11.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 OAJ29736.1 - 8.4e-05 22.4 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Chromo PF00385.24 OAJ29736.1 - 0.00025 20.9 0.1 0.0007 19.4 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 OAJ29736.1 - 0.00026 20.9 0.0 1.1 9.2 0.0 3.2 3 0 0 3 3 3 2 NACHT domain G-alpha PF00503.20 OAJ29736.1 - 0.00036 19.8 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit DUF87 PF01935.17 OAJ29736.1 - 0.00046 20.4 3.3 0.038 14.1 0.2 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain AAA_30 PF13604.6 OAJ29736.1 - 0.00072 19.3 0.5 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAJ29736.1 - 0.00077 19.8 0.0 1.1 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase 4HB PF17947.1 OAJ29736.1 - 0.00085 19.3 0.0 0.0043 17.1 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain ATPase_2 PF01637.18 OAJ29736.1 - 0.0011 19.0 0.7 1.9 8.4 0.0 3.7 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 OAJ29736.1 - 0.0012 19.1 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.6 OAJ29736.1 - 0.0012 19.3 1.9 8.6 7.0 0.0 4.8 5 0 0 5 5 4 0 HEAT-like repeat AAA_33 PF13671.6 OAJ29736.1 - 0.0012 19.0 0.1 2 8.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain CLASP_N PF12348.8 OAJ29736.1 - 0.0013 18.4 0.1 0.95 9.0 0.0 2.5 1 1 1 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 OAJ29736.1 - 0.0015 18.9 0.2 0.2 12.0 0.0 4.1 4 1 1 5 5 3 1 HEAT repeats AAA_16 PF13191.6 OAJ29736.1 - 0.0015 18.9 0.0 0.75 10.2 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 OAJ29736.1 - 0.0017 17.1 0.1 1.8 7.1 0.0 3.3 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 OAJ29736.1 - 0.0025 17.1 0.0 1.4 8.1 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 OAJ29736.1 - 0.003 16.6 0.2 0.38 9.7 0.0 2.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 OAJ29736.1 - 0.0038 17.4 0.1 0.57 10.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 OAJ29736.1 - 0.0041 17.5 0.0 7.4 7.0 0.0 4.4 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 OAJ29736.1 - 0.0064 16.2 0.0 0.54 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 OAJ29736.1 - 0.0074 16.5 1.6 3.8 8.0 0.0 4.6 6 0 0 6 6 3 1 HEAT repeat Roc PF08477.13 OAJ29736.1 - 0.025 14.8 0.0 6.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 OAJ29736.1 - 0.041 13.5 0.0 2.5 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ29736.1 - 0.047 13.0 0.1 7.5 5.8 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 OAJ29736.1 - 0.047 13.5 0.3 4.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 OAJ29736.1 - 0.052 13.6 0.1 14 5.7 0.0 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 OAJ29736.1 - 0.062 12.4 0.1 11 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAJ29736.1 - 0.071 13.1 2.1 11 6.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 OAJ29736.1 - 0.081 13.0 0.0 17 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 OAJ29736.1 - 0.09 12.7 0.0 10 6.0 0.1 2.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 OAJ29736.1 - 0.12 11.9 0.2 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 OAJ29736.1 - 0.29 10.7 3.1 14 5.3 0.0 3.5 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain Solute_trans_a PF03619.16 OAJ29737.1 - 2.5e-79 266.5 12.7 3.1e-79 266.2 12.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WD40 PF00400.32 OAJ29738.1 - 1.1e-15 57.7 8.8 0.0085 16.9 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 OAJ29738.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CDC45 PF02724.14 OAJ29738.1 - 0.87 7.8 14.4 1.3 7.2 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein GCIP PF13324.6 OAJ29738.1 - 1 8.9 10.8 1.8 8.1 10.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Vfa1 PF08432.10 OAJ29738.1 - 2.8 8.3 9.6 7.2 6.9 9.6 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.11 OAJ29738.1 - 4.8 7.0 7.0 13 5.6 7.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) LRS4 PF10422.9 OAJ29739.1 - 0.28 10.7 9.4 0.78 9.3 0.5 2.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 SDA1 PF05285.12 OAJ29739.1 - 4.9 6.5 38.1 5.2 6.4 21.6 2.2 2 0 0 2 2 2 0 SDA1 PET117 PF15786.5 OAJ29739.1 - 9.1 6.6 7.6 27 5.1 7.6 1.7 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial AAA PF00004.29 OAJ29740.1 - 7.5e-19 68.5 0.0 4.8e-09 36.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ29740.1 - 2.1e-13 50.7 1.5 8.5e-13 48.7 1.5 2.0 1 1 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 OAJ29740.1 - 0.0014 19.0 0.7 0.009 16.4 0.6 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 OAJ29740.1 - 0.0066 16.3 0.1 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ29740.1 - 0.029 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 OAJ29740.1 - 0.033 14.4 0.1 0.39 11.0 0.0 2.6 1 1 1 2 2 2 0 AAA domain Pex14_N PF04695.13 OAJ29740.1 - 0.079 13.6 12.0 2.2 8.9 0.4 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM240 PF15207.6 OAJ29740.1 - 0.11 12.2 0.2 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 TMEM240 family ABC_tran PF00005.27 OAJ29740.1 - 0.14 12.7 0.1 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Med22 PF06179.12 OAJ29741.1 - 2e-14 53.7 0.2 3e-14 53.1 0.2 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Brix PF04427.18 OAJ29742.1 - 4.9e-34 118.1 0.0 6.7e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.12 OAJ29742.1 - 0.37 9.0 34.6 0.5 8.5 34.6 1.2 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 OAJ29742.1 - 1.7 8.0 25.6 2.8 7.3 25.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CNDH2_C PF16858.5 OAJ29742.1 - 2 8.2 10.3 3.6 7.4 10.3 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Paf1 PF03985.13 OAJ29742.1 - 2.2 7.2 15.9 3.8 6.4 15.9 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 OAJ29742.1 - 6.6 4.9 24.6 10 4.3 24.6 1.3 1 0 0 1 1 1 0 CDC45-like protein PIG-X PF08320.12 OAJ29744.1 - 1.5e-19 70.8 0.0 1.5e-10 41.4 0.0 2.9 2 1 0 2 2 2 2 PIG-X / PBN1 Hist_deacetyl PF00850.19 OAJ29745.1 - 4.8e-38 131.4 0.0 9.2e-38 130.4 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain Rad17 PF03215.15 OAJ29746.1 - 5.4e-17 62.3 0.0 9.9e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 OAJ29746.1 - 0.00039 20.7 0.0 0.0011 19.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ29746.1 - 0.00057 20.3 0.5 0.0029 18.0 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 OAJ29746.1 - 0.016 15.7 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 OAJ29746.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 OAJ29746.1 - 0.077 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 OAJ29746.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA PF00004.29 OAJ29746.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAJ29746.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain 4_1_CTD PF05902.13 OAJ29746.1 - 0.79 9.8 5.1 0.15 12.2 1.2 1.8 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) Zn_clus PF00172.18 OAJ29747.1 - 2.1e-08 34.1 7.6 3.4e-08 33.5 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMR1 PF08505.10 OAJ29747.1 - 1.4 9.2 9.0 2.5 8.3 9.0 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Phosphodiest PF01663.22 OAJ29748.1 - 1.4e-57 195.9 0.2 2.9e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 OAJ29748.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Spt5_N PF11942.8 OAJ29748.1 - 0.92 10.5 8.6 0.42 11.6 2.3 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic PF14632.6 OAJ29748.1 - 1.7 9.3 11.4 0.21 12.2 5.5 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L1 PF00687.21 OAJ29749.1 - 6.6e-48 163.2 0.0 1.3e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family PPP4R2 PF09184.11 OAJ29749.1 - 9.9 5.7 18.5 0.3 10.6 10.3 2.1 2 0 0 2 2 2 0 PPP4R2 CAP_GLY PF01302.25 OAJ29750.1 - 4.2e-14 52.3 0.4 7.6e-14 51.5 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain zf-CCHC_4 PF14392.6 OAJ29750.1 - 0.0034 17.1 3.7 0.076 12.8 0.5 2.5 2 0 0 2 2 2 2 Zinc knuckle DUF3087 PF11286.8 OAJ29750.1 - 0.62 9.5 2.9 1.4 8.4 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF1943 PF09172.11 OAJ29750.1 - 2.1 7.5 9.1 0.71 9.1 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Snf7 PF03357.21 OAJ29751.1 - 8.7e-19 67.8 7.3 1.2e-18 67.3 7.3 1.2 1 0 0 1 1 1 1 Snf7 EphA2_TM PF14575.6 OAJ29752.1 - 0.034 15.0 0.0 0.067 14.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 OAJ29752.1 - 0.065 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 TNFR_16_TM PF18422.1 OAJ29752.1 - 1.2 9.1 3.7 1.6 8.8 1.2 2.0 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF572 PF04502.13 OAJ29753.1 - 2.2e-64 218.2 2.8 2.6e-64 218.0 2.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3052 PF11253.8 OAJ29753.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) DUF866 PF05907.13 OAJ29753.1 - 0.042 13.8 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Zn-ribbon_8 PF09723.10 OAJ29753.1 - 0.33 11.1 2.1 0.47 10.6 0.5 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Seryl_tRNA_N PF02403.22 OAJ29754.1 - 0.082 13.1 0.7 0.21 11.8 0.7 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.15 OAJ29754.1 - 1.5 9.0 6.7 0.81 9.8 2.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Pectate_lyase_3 PF12708.7 OAJ29755.1 - 1.3e-78 263.7 6.0 5e-62 209.5 1.7 3.0 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 OAJ29755.1 - 1.8e-05 24.3 2.0 0.045 13.5 0.0 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Sec15 PF04091.12 OAJ29756.1 - 2.7e-21 76.3 0.2 1.5e-20 73.8 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 OAJ29756.1 - 8.1e-07 29.0 0.8 5.1e-06 26.4 0.1 2.6 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG5 PF10392.9 OAJ29756.1 - 0.00025 21.2 0.6 0.0082 16.3 0.1 2.9 2 1 1 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.11 OAJ29756.1 - 0.0056 16.7 0.2 0.051 13.7 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 OAJ29756.1 - 0.047 13.5 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 CENP-F_leu_zip PF10473.9 OAJ29756.1 - 0.048 13.7 0.7 0.41 10.6 0.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1484 PF07363.11 OAJ29756.1 - 0.089 13.8 1.2 22 6.1 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) COG2 PF06148.11 OAJ29756.1 - 0.49 10.5 3.8 0.29 11.2 0.6 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LapA_dom PF06305.11 OAJ29757.1 - 0.021 14.7 0.8 0.043 13.6 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NOA36 PF06524.12 OAJ29757.1 - 0.45 9.8 4.8 0.89 8.8 4.8 1.4 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 OAJ29758.1 - 1.1e-68 231.4 0.0 1.3e-68 231.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29758.1 - 1.3e-33 116.4 0.0 1.6e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ29758.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ29758.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ29758.1 - 0.16 11.9 2.8 0.19 11.6 0.9 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Bestrophin PF01062.21 OAJ29760.1 - 6.9e-15 55.2 0.1 4.3e-08 32.9 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF591 PF04569.14 OAJ29760.1 - 0.016 15.3 0.2 0.04 14.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF2347 PF09804.9 OAJ29761.1 - 6.4e-29 101.4 0.0 3.4e-28 99.0 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 OAJ29761.1 - 0.0019 17.0 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Afi1 PF07792.12 OAJ29761.1 - 0.03 14.8 3.3 0.3 11.6 0.0 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nuc_recep-AF1 PF11825.8 OAJ29761.1 - 0.29 11.2 5.6 0.76 9.8 4.5 2.3 1 1 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 PPP4R2 PF09184.11 OAJ29761.1 - 10 5.6 6.3 6.6 6.2 0.6 2.3 2 0 0 2 2 2 0 PPP4R2 Fungal_trans PF04082.18 OAJ29762.1 - 1.8e-28 99.3 0.0 3.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain tRNA-synt_1c PF00749.21 OAJ29763.1 - 7.3e-107 356.9 0.0 1.3e-106 356.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 OAJ29763.1 - 4.8e-36 124.2 0.2 7.7e-36 123.6 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 OAJ29763.1 - 0.013 15.6 0.2 0.12 12.6 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ29763.1 - 0.026 14.7 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ29763.1 - 0.028 14.5 0.4 0.1 12.6 0.4 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSS1_SEM1 PF05160.13 OAJ29763.1 - 0.032 14.3 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 DSS1/SEM1 family tRNA-synt_1e PF01406.19 OAJ29763.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain CS PF04969.16 OAJ29764.1 - 7.8e-08 33.2 0.0 2.4e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 CS domain Isochorismatase PF00857.20 OAJ29765.1 - 1.2e-22 80.9 0.1 3e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family zf-ZPR1 PF03367.13 OAJ29766.1 - 1.1e-105 350.3 0.4 3.7e-52 176.4 0.0 2.7 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 OAJ29766.1 - 0.013 15.5 3.8 0.68 10.0 0.4 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 OAJ29766.1 - 0.024 14.7 8.4 6 7.0 0.4 3.3 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type DZR PF12773.7 OAJ29766.1 - 0.049 13.7 8.6 3.4 7.8 0.2 4.1 3 1 0 4 4 4 0 Double zinc ribbon DUF2688 PF10892.8 OAJ29766.1 - 0.11 11.9 0.1 0.41 10.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) zinc-ribbons_6 PF07191.12 OAJ29766.1 - 3.8 7.6 7.8 16 5.5 0.6 3.1 3 1 0 3 3 3 0 zinc-ribbons tRNA-synt_2b PF00587.25 OAJ29767.1 - 2.3e-29 102.6 0.0 4.7e-29 101.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ29767.1 - 0.00013 22.1 0.0 0.00033 20.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Kinesin PF00225.23 OAJ29768.1 - 7.2e-110 367.0 0.0 1.2e-109 366.2 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 OAJ29768.1 - 2.7e-41 141.7 4.6 7.2e-33 114.2 1.2 3.1 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 OAJ29768.1 - 2.2e-33 116.1 0.1 7.9e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 OAJ29768.1 - 3.6e-25 88.6 0.0 8.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 OAJ29768.1 - 4.2e-16 59.4 0.1 1.3e-15 57.8 0.1 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 OAJ29768.1 - 1.9e-09 37.8 0.1 5.7e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 OAJ29768.1 - 1.1e-05 25.7 0.0 4.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain PH_11 PF15413.6 OAJ29768.1 - 0.064 13.7 0.1 0.25 11.8 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain SQHop_cyclase_C PF13243.6 OAJ29769.1 - 1.6e-47 162.1 2.6 8.3e-46 156.5 0.7 2.5 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 OAJ29769.1 - 8.1e-47 159.7 0.0 2.8e-37 128.4 0.0 4.3 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 OAJ29769.1 - 1.1e-30 105.0 11.6 1.5e-08 34.2 0.0 7.4 8 0 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 OAJ29769.1 - 1.2e-06 27.7 0.5 0.005 15.9 0.1 4.1 1 1 2 4 4 4 2 A-macroglobulin TED domain Pec_lyase PF09492.10 OAJ29769.1 - 0.0028 17.0 0.2 2.6 7.3 0.0 4.0 1 1 0 3 3 3 1 Pectic acid lyase Ank_2 PF12796.7 OAJ29770.1 - 2.5e-12 47.2 0.2 1.8e-10 41.3 0.3 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ29770.1 - 2.6e-10 39.6 0.3 0.00048 20.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 OAJ29770.1 - 7.7e-10 39.1 0.2 0.0037 17.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 OAJ29770.1 - 1.4e-08 34.8 0.4 9.8e-05 22.6 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 OAJ29770.1 - 2e-08 34.3 0.6 0.0013 19.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat SPT16 PF08644.11 OAJ29770.1 - 0.048 13.8 0.1 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) UPF0524 PF15823.5 OAJ29770.1 - 0.055 12.9 0.6 0.12 11.7 0.6 1.5 1 0 0 1 1 1 0 UPF0524 of C3orf70 PIEZO PF15917.5 OAJ29770.1 - 0.35 10.3 1.7 0.56 9.7 1.7 1.3 1 0 0 1 1 1 0 Piezo Rtf2 PF04641.12 OAJ29770.1 - 3.8 6.8 12.3 0.16 11.3 3.5 2.5 2 1 1 3 3 3 0 Rtf2 RING-finger WD40 PF00400.32 OAJ29773.1 - 8.9e-30 102.3 19.6 2.1e-06 28.3 1.5 9.5 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29773.1 - 6.2e-07 29.6 1.5 0.077 13.3 0.0 5.2 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ29773.1 - 5.4e-05 22.3 0.1 1 8.3 0.0 4.0 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Metallopep PF12044.8 OAJ29774.1 - 2.3e-10 39.7 0.0 5.4e-09 35.2 0.0 2.0 2 0 0 2 2 2 2 Putative peptidase family SUIM_assoc PF16619.5 OAJ29775.1 - 0.0084 16.2 1.6 0.0084 16.2 1.6 2.2 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 OAJ29775.1 - 0.055 13.6 7.8 0.14 12.3 7.4 1.9 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Spt20 PF12090.8 OAJ29775.1 - 1.2 8.7 7.7 2.7 7.5 7.7 1.5 1 0 0 1 1 1 0 Spt20 family 2-oxoacid_dh PF00198.23 OAJ29776.1 - 4.4e-53 180.1 0.0 9.8e-53 179.0 0.0 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ29776.1 - 4.7e-19 68.0 0.1 7.3e-19 67.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ29776.1 - 4.2e-15 55.8 0.1 1.1e-14 54.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ29776.1 - 0.023 14.5 0.0 0.082 12.7 0.0 1.9 1 1 1 2 2 2 0 Biotin-lipoyl like PYNP_C PF07831.13 OAJ29776.1 - 0.087 12.5 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.7 OAJ29776.1 - 0.12 11.1 0.0 0.39 9.4 0.0 1.6 1 1 1 2 2 2 0 HlyD family secretion protein RTA1 PF04479.13 OAJ29778.1 - 3.7e-48 163.9 10.2 5.5e-48 163.3 10.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Phage_integrase PF00589.22 OAJ29779.1 - 9.7e-06 25.5 0.0 5.7e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Phage integrase family Clathrin PF00637.20 OAJ29780.1 - 5.7e-15 55.4 0.4 3.5e-06 26.9 0.0 3.5 3 0 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.8 OAJ29780.1 - 8.7e-11 41.9 0.5 8.7e-11 41.9 0.5 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 OAJ29780.1 - 1.1e-09 38.2 7.0 2.5e-09 37.0 7.0 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 OAJ29780.1 - 0.0032 17.3 7.3 0.0054 16.5 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ29780.1 - 0.054 13.8 6.5 0.096 13.0 6.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAJ29780.1 - 0.14 12.1 6.5 0.24 11.4 6.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.22 OAJ29780.1 - 1.2 9.1 6.9 2.2 8.2 6.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_UBOX PF13445.6 OAJ29780.1 - 1.4 9.0 5.7 2.9 8.0 5.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ29780.1 - 7.2 6.6 6.6 13 5.8 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_3 PF13456.6 OAJ29781.1 - 0.0015 18.3 0.1 0.0039 17.0 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like DNA_pol_viral_C PF00336.18 OAJ29781.1 - 0.027 13.9 0.0 0.062 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain AAA_25 PF13481.6 OAJ29782.1 - 0.037 13.6 0.2 3.6 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 OAJ29782.1 - 0.073 12.4 0.0 6.4 6.0 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Sgf11 PF08209.11 OAJ29782.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Band_7 PF01145.25 OAJ29783.1 - 8.8e-07 29.1 0.0 8.8e-07 29.1 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Carn_acyltransf PF00755.20 OAJ29785.1 - 4.4e-189 629.9 0.0 5.1e-189 629.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Mito_carr PF00153.27 OAJ29786.1 - 4.6e-65 215.6 2.6 1.1e-21 76.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MTABC_N PF16185.5 OAJ29787.1 - 0.42 10.1 4.3 0.95 8.9 4.3 1.6 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region TcpE PF12648.7 OAJ29787.1 - 0.83 10.2 3.7 0.93 10.1 0.6 2.4 2 1 0 2 2 2 0 TcpE family DUF4017 PF13209.6 OAJ29787.1 - 0.94 9.5 5.0 0.31 11.0 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) DUF3087 PF11286.8 OAJ29787.1 - 6.8 6.1 6.4 0.77 9.2 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) AIM5 PF17050.5 OAJ29788.1 - 3.8e-05 24.4 3.6 4.5e-05 24.2 0.9 2.2 2 1 0 2 2 2 1 Altered inheritance of mitochondria 5 DUF883 PF05957.13 OAJ29788.1 - 0.051 14.2 0.7 0.051 14.2 0.7 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) CitMHS PF03600.16 OAJ29789.1 - 0.19 10.9 4.3 4.1 6.5 1.9 2.5 2 0 0 2 2 2 0 Citrate transporter RNA_pol_Rpb2_6 PF00562.28 OAJ29790.1 - 9.1e-109 364.1 0.0 2.6e-108 362.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ29790.1 - 8.2e-36 123.4 0.0 1.5e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 OAJ29790.1 - 1.9e-27 95.2 0.0 5.1e-27 93.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 OAJ29790.1 - 6.6e-24 83.7 0.0 1.4e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 OAJ29790.1 - 1.4e-19 70.4 0.0 3.3e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ29790.1 - 1.5e-17 63.8 0.2 8.9e-15 54.9 0.1 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 FAM220 PF15487.6 OAJ29791.1 - 0.025 14.2 2.1 0.039 13.6 2.1 1.2 1 0 0 1 1 1 0 FAM220 family DUF4203 PF13886.6 OAJ29792.1 - 3.4e-45 154.2 23.6 5e-45 153.7 23.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HCMV_UL124 PF17609.2 OAJ29792.1 - 0.015 15.5 6.7 0.015 15.5 6.7 2.7 2 1 1 3 3 3 0 Family of unknown function TssN PF17555.2 OAJ29792.1 - 1.2 8.4 2.3 2.1 7.6 2.3 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Parvo_NS1 PF01057.17 OAJ29793.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2785 PF10978.8 OAJ29793.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2785) ThuA PF06283.11 OAJ29794.1 - 2.8e-38 132.3 6.8 1.1e-28 100.9 0.3 3.0 3 0 0 3 3 3 2 Trehalose utilisation Pkinase PF00069.25 OAJ29795.1 - 7.3e-66 222.2 0.0 9e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29795.1 - 1.8e-28 99.5 0.1 2.9e-28 98.9 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ29795.1 - 3.3e-05 23.3 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ29795.1 - 3.7e-05 23.2 0.4 7.1e-05 22.3 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ29795.1 - 0.0026 16.8 0.1 0.0038 16.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ29795.1 - 0.01 15.8 0.7 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ29795.1 - 0.058 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family HAD_2 PF13419.6 OAJ29798.1 - 4.4e-10 39.9 0.0 1.1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ29798.1 - 2.9e-09 37.6 0.0 8.8e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ29798.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like SCO1-SenC PF02630.14 OAJ29799.1 - 2e-41 141.0 0.0 3.2e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 OAJ29799.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.9 1 1 0 1 1 1 0 AhpC/TSA family DASH_Ask1 PF08655.10 OAJ29800.1 - 5.9e-28 96.6 0.0 9.3e-28 95.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 PBP1_TM PF14812.6 OAJ29800.1 - 9.1 6.7 11.9 1.4e+02 3.0 0.1 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal OHCU_decarbox PF09349.10 OAJ29801.1 - 5.3e-22 79.0 0.0 1.3e-21 77.8 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase Glyco_hydro_18 PF00704.28 OAJ29802.1 - 2.4e-56 191.8 0.4 2.8e-56 191.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2002 PF09400.10 OAJ29802.1 - 0.07 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) MutS_V PF00488.21 OAJ29803.1 - 2.1e-50 171.4 0.0 3.4e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ29803.1 - 1.9e-07 31.5 1.0 1.9e-07 31.5 1.0 2.8 2 1 1 3 3 3 1 MutS domain III AAA_29 PF13555.6 OAJ29803.1 - 0.023 14.4 0.1 0.073 12.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 OAJ29803.1 - 0.079 12.5 1.3 0.19 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 OAJ29803.1 - 0.87 10.1 0.0 0.87 10.1 0.0 2.6 4 0 0 4 4 4 0 AAA domain Ras PF00071.22 OAJ29804.1 - 3.6e-57 192.5 0.1 4.2e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ29804.1 - 6.1e-32 110.4 0.0 9.4e-32 109.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ29804.1 - 4.4e-14 52.3 0.0 5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 OAJ29804.1 - 6.5e-08 32.7 0.0 1.2e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ29804.1 - 1.3e-06 28.1 0.1 4.4e-05 23.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 OAJ29804.1 - 5.5e-06 25.9 0.1 7e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAJ29804.1 - 4.5e-05 23.4 0.2 0.0042 17.0 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 OAJ29804.1 - 0.00041 20.2 0.5 0.016 15.0 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 OAJ29804.1 - 0.0013 18.5 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAJ29804.1 - 0.0049 16.2 0.2 0.076 12.3 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 OAJ29804.1 - 0.0063 16.1 0.0 0.024 14.2 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 OAJ29804.1 - 0.0084 16.5 0.1 0.019 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ29804.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ29804.1 - 0.016 15.0 0.0 0.04 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 OAJ29804.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 OAJ29804.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 OAJ29804.1 - 0.036 14.1 0.0 0.074 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 OAJ29804.1 - 0.051 13.5 0.3 0.099 12.5 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 OAJ29804.1 - 0.056 13.7 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 NACHT PF05729.12 OAJ29804.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 OAJ29804.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 OAJ29804.1 - 0.15 11.2 0.2 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 TMEM223 PF14640.6 OAJ29805.1 - 0.01 16.0 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 223 zf-P11 PF03854.14 OAJ29806.1 - 0.057 13.1 0.4 0.057 13.1 0.4 2.2 2 0 0 2 2 2 0 P-11 zinc finger HscB_4_cys PF18256.1 OAJ29806.1 - 7.5 6.5 7.6 0.55 10.1 1.8 2.0 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif ATG16 PF08614.11 OAJ29807.1 - 2.7e-46 158.3 23.9 3.3e-46 158.0 23.9 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 OAJ29807.1 - 0.0031 16.6 7.7 0.0031 16.6 7.7 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 OAJ29807.1 - 0.17 13.0 12.1 2.7 9.2 3.3 3.1 2 1 2 4 4 4 0 Protein SOGA SHE3 PF17078.5 OAJ29807.1 - 0.28 10.9 12.7 0.1 12.3 10.3 1.4 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 RAP1 PF07218.11 OAJ29807.1 - 0.44 8.8 2.5 0.4 8.9 1.5 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V_ATPase_I PF01496.19 OAJ29807.1 - 0.45 8.4 4.1 0.14 10.1 1.5 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 OAJ29807.1 - 0.47 10.9 6.1 6.2 7.3 0.6 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FlgN PF05130.12 OAJ29807.1 - 0.75 10.3 16.7 0.073 13.6 5.9 2.5 1 1 1 2 2 2 0 FlgN protein Fib_alpha PF08702.10 OAJ29807.1 - 1.1 9.4 14.0 0.097 12.9 6.6 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 OAJ29807.1 - 1.5 9.4 23.3 1.3 9.5 10.2 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 OAJ29807.1 - 1.6 9.1 4.3 18 5.6 1.7 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 OAJ29807.1 - 2.1 9.0 16.2 2.3 8.9 2.9 3.0 2 1 1 3 3 3 0 Initiation control protein YabA FAM76 PF16046.5 OAJ29807.1 - 2.6 7.3 8.7 20 4.4 8.7 2.0 1 1 0 1 1 1 0 FAM76 protein OmpH PF03938.14 OAJ29807.1 - 7.5 6.9 16.1 4 7.8 11.6 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) ATP-synt_ab PF00006.25 OAJ29808.1 - 6.3e-106 352.8 0.0 8.9e-106 352.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 OAJ29808.1 - 4.3e-43 146.0 0.0 7.6e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 OAJ29808.1 - 3.5e-14 53.1 3.1 1e-13 51.6 3.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Methyltransf_12 PF08242.12 OAJ29809.1 - 0.041 14.6 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain LRS4 PF10422.9 OAJ29809.1 - 0.26 10.8 3.3 0.36 10.4 3.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 THEG4 PF15834.5 OAJ29809.1 - 0.39 10.7 1.4 0.6 10.1 1.4 1.2 1 0 0 1 1 1 0 Testis highly expressed protein 4 MRP-S31 PF15433.6 OAJ29811.1 - 0.049 13.3 10.1 0.056 13.1 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 GET2 PF08690.10 OAJ29811.1 - 0.11 12.2 17.1 0.13 11.9 17.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PPP4R2 PF09184.11 OAJ29811.1 - 0.37 10.3 7.3 0.42 10.1 7.3 1.1 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.16 OAJ29811.1 - 0.5 10.4 8.4 0.66 10.0 8.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 OAJ29811.1 - 0.87 9.4 7.6 0.95 9.2 7.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 OAJ29811.1 - 1.1 8.2 9.1 1.2 8.0 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 OAJ29811.1 - 1.9 7.2 15.7 2.2 7.0 15.7 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 OAJ29811.1 - 2.1 6.2 5.9 2.4 6.0 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCSAP PF15748.5 OAJ29811.1 - 2.7 8.1 19.6 3.6 7.7 19.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF1631 PF07793.11 OAJ29811.1 - 4.7 5.5 29.5 5.6 5.3 29.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF572 PF04502.13 OAJ29811.1 - 9 5.8 13.9 12 5.4 13.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rhodanese PF00581.20 OAJ29813.1 - 3.4e-06 27.5 0.0 4.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain ECH_1 PF00378.20 OAJ29814.1 - 3.7e-17 62.5 0.0 9.1e-17 61.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ29814.1 - 2.2e-07 30.7 0.0 5e-07 29.5 0.0 1.5 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 OAJ29816.1 - 2.5e-66 223.8 0.0 4.3e-34 118.1 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29816.1 - 2e-30 105.9 0.0 7.6e-15 54.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 OAJ29816.1 - 2.1e-18 66.7 0.0 5e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.7 OAJ29816.1 - 3.3e-18 66.2 2.8 5.3e-18 65.5 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 OAJ29816.1 - 3.8e-13 49.4 1.1 1.2e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 OAJ29816.1 - 6e-06 26.3 0.0 6e-06 26.3 0.0 3.6 4 1 0 4 4 4 1 Phosphotransferase enzyme family FTA2 PF13095.6 OAJ29816.1 - 0.0013 18.4 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 OAJ29816.1 - 0.0018 17.7 0.6 0.012 14.9 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 OAJ29816.1 - 0.032 13.0 0.0 0.032 13.0 0.0 1.9 2 1 0 2 2 2 0 Fungal protein kinase Methyltransf_16 PF10294.9 OAJ29817.1 - 6.4e-18 65.1 0.0 2e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 OAJ29817.1 - 0.00033 21.3 0.0 0.00075 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29817.1 - 0.0052 17.5 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ29817.1 - 0.046 13.3 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 OAJ29817.1 - 0.24 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase ING PF12998.7 OAJ29819.1 - 3.2e-11 43.7 0.0 5.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 OAJ29819.1 - 1.9e-05 24.4 8.8 3.3e-05 23.7 8.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4390 PF14334.6 OAJ29819.1 - 0.19 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4390) zf-C4pol PF14260.6 OAJ29819.1 - 0.22 12.0 5.0 0.26 11.8 1.1 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DDHD PF02862.17 OAJ29821.1 - 3.1e-27 96.2 0.0 3.1e-27 96.2 0.0 3.6 3 1 0 3 3 3 1 DDHD domain DnaJ PF00226.31 OAJ29822.1 - 9.7e-18 64.1 0.2 1.7e-17 63.2 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3325 PF11804.8 OAJ29822.1 - 0.8 9.9 5.0 0.19 11.9 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) Abhydrolase_6 PF12697.7 OAJ29826.1 - 1.4e-05 25.8 2.0 1.4e-05 25.8 2.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ29826.1 - 0.0072 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1749 PF08538.10 OAJ29826.1 - 0.046 12.8 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 OAJ29826.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) SURF1 PF02104.15 OAJ29828.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 SURF1 family YL1 PF05764.13 OAJ29828.1 - 0.083 13.0 8.1 0.14 12.3 8.1 1.4 1 1 0 1 1 1 0 YL1 nuclear protein OrfB_IS605 PF01385.19 OAJ29829.1 - 0.00099 19.3 7.8 0.0087 16.3 0.8 2.9 1 1 1 2 2 2 2 Probable transposase OrfB_Zn_ribbon PF07282.11 OAJ29829.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF3106 PF11304.8 OAJ29829.1 - 1.5 9.4 12.4 1 9.8 1.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) ADH_zinc_N PF00107.26 OAJ29831.1 - 4.2e-12 46.2 0.0 8.8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ29831.1 - 5.9e-09 35.8 1.2 1.1e-07 31.6 1.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 OAJ29831.1 - 0.00016 22.7 0.0 0.00028 21.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DEC-1_N PF04625.13 OAJ29832.1 - 0.57 9.1 6.2 0.55 9.2 6.2 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4148 PF13663.6 OAJ29832.1 - 1.6 8.9 9.0 1.9 8.7 9.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) RabGAP-TBC PF00566.18 OAJ29833.1 - 2e-17 63.6 0.0 3.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PARP PF00644.20 OAJ29834.1 - 3.7e-05 23.4 0.5 0.00026 20.6 0.5 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain bZIP_1 PF00170.21 OAJ29836.1 - 3.8e-05 23.7 4.6 0.00011 22.3 4.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ29836.1 - 0.00024 21.1 4.9 0.00051 20.1 4.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Allexi_40kDa PF05549.11 OAJ29836.1 - 0.014 15.0 0.6 0.045 13.3 0.6 1.9 1 0 0 1 1 1 0 Allexivirus 40kDa protein Herpes_BLRF2 PF05812.12 OAJ29836.1 - 0.019 15.1 1.9 0.099 12.8 1.9 2.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein LCD1 PF09798.9 OAJ29836.1 - 0.074 11.6 0.1 0.099 11.1 0.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Spc24 PF08286.11 OAJ29836.1 - 0.14 12.4 0.4 0.31 11.3 0.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 PALP PF00291.25 OAJ29837.1 - 5.2e-48 163.9 6.5 1.2e-46 159.5 6.5 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 OAJ29837.1 - 0.082 12.7 0.5 0.19 11.6 0.5 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Pkinase PF00069.25 OAJ29838.1 - 7.1e-60 202.6 0.0 2.8e-40 138.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29838.1 - 5.6e-26 91.4 0.0 9.3e-21 74.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 OAJ29838.1 - 2.3e-10 40.6 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 OAJ29838.1 - 2.2e-07 30.5 0.0 2.1e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ29838.1 - 0.00068 19.6 0.0 0.012 15.5 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ29838.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_4 PF08448.10 OAJ29838.1 - 0.02 15.1 0.0 0.073 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Kdo PF06293.14 OAJ29838.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ29838.1 - 0.025 14.2 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 OAJ29838.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family OKR_DC_1_N PF03709.15 OAJ29838.1 - 0.18 12.1 0.0 0.48 10.7 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Glyco_transf_90 PF05686.12 OAJ29839.1 - 1.5e-25 90.0 6.5 1.4e-22 80.2 6.6 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF3533 PF12051.8 OAJ29840.1 - 4.3e-73 246.4 11.0 5.5e-73 246.1 11.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Ibs_toxin PF13956.6 OAJ29840.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.4 2 0 0 2 2 2 0 Toxin Ibs, type I toxin-antitoxin system EphA2_TM PF14575.6 OAJ29840.1 - 5.8 7.9 5.5 22 6.0 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain HAD_2 PF13419.6 OAJ29841.1 - 2.5e-17 63.5 0.0 1.1e-11 45.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ29841.1 - 1.2e-14 55.1 0.6 4.3e-14 53.3 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 OAJ29841.1 - 3.8e-05 23.7 0.0 8.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 OAJ29841.1 - 0.028 14.8 0.0 0.57 10.6 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase GDPD PF03009.17 OAJ29842.1 - 8.5e-34 117.4 2.1 3.9e-33 115.3 2.1 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 OAJ29842.1 - 2.7e-05 24.5 2.9 6.8e-05 23.2 2.9 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Stevor PF17410.2 OAJ29843.1 - 0.01 15.4 0.2 0.016 14.8 0.2 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1180 PF06679.12 OAJ29843.1 - 2.3 8.6 13.9 1.3 9.4 4.8 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2905 PF11146.8 OAJ29843.1 - 3.2 8.0 5.3 0.38 11.0 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) DUF3533 PF12051.8 OAJ29844.1 - 3.8e-79 266.4 17.8 4.4e-79 266.1 17.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) BatD PF13584.6 OAJ29844.1 - 0.18 10.6 1.5 8.4 5.1 0.0 2.2 2 0 0 2 2 2 0 Oxygen tolerance CDH-cyt PF16010.5 OAJ29845.1 - 1.2e-12 47.9 4.3 2.6e-12 46.8 4.3 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 OAJ29845.1 - 6.3e-09 36.1 8.7 6.3e-09 36.1 8.7 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 OAJ29845.1 - 0.0042 17.3 0.1 0.0093 16.2 0.1 1.7 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 OAJ29845.1 - 0.0084 16.3 8.5 0.029 14.5 8.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Ecl1 PF12855.7 OAJ29845.1 - 1.1 10.4 13.4 1.8 9.7 13.4 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2427 PF10348.9 OAJ29845.1 - 1.5 8.6 8.8 0.62 9.9 5.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) MULE PF10551.9 OAJ29849.1 - 4.8e-21 75.0 0.1 1.1e-20 73.8 0.1 1.7 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 OAJ29849.1 - 2.5e-07 31.3 2.7 3e-06 27.8 0.6 2.6 2 0 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 OAJ29849.1 - 0.0021 18.5 0.1 0.0049 17.2 0.1 1.6 1 0 0 1 1 1 1 Transcription factor AFT PEX11 PF05648.14 OAJ29850.1 - 6.8e-63 212.1 2.3 7.7e-63 211.9 2.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lactamase_B_6 PF16661.5 OAJ29851.1 - 1.8e-41 141.8 0.0 7e-23 81.1 0.0 3.3 3 0 0 3 3 3 3 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 OAJ29851.1 - 4.9e-33 114.7 0.0 4.9e-33 114.7 0.0 3.4 5 0 0 5 5 5 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 OAJ29851.1 - 2.6e-14 53.4 0.0 8.4e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Beta-prism_lec PF16458.5 OAJ29851.1 - 0.092 12.7 0.4 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 Beta-prism lectin RMMBL PF07521.12 OAJ29851.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain Acyltransferase PF01553.21 OAJ29852.1 - 4.4e-34 117.0 0.0 6.2e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Popeye PF04831.13 OAJ29852.1 - 0.13 12.5 0.6 0.2 11.8 0.6 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Med3 PF11593.8 OAJ29854.1 - 0.00073 18.8 6.9 0.00073 18.8 6.9 2.1 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DnaJ PF00226.31 OAJ29855.1 - 1.1e-19 70.3 0.2 1.9e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1682 PF07946.14 OAJ29855.1 - 0.58 9.3 10.7 0.76 8.9 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF202 PF02656.15 OAJ29856.1 - 7.5e-14 51.9 5.3 7.5e-14 51.9 5.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX2_TM PF02790.15 OAJ29856.1 - 0.0037 17.4 0.7 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane domain DUF5337 PF17272.2 OAJ29856.1 - 1.3 8.9 6.6 1.9 8.4 5.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF2615 PF11027.8 OAJ29856.1 - 3.1 8.0 3.9 1.7 8.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF2673 PF10880.8 OAJ29857.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DASH_Spc19 PF08287.11 OAJ29858.1 - 1.4e-05 25.0 0.1 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 Spc19 SR-25 PF10500.9 OAJ29858.1 - 0.22 11.1 2.5 0.27 10.8 2.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF913 PF06025.12 OAJ29859.1 - 1.3e-91 307.3 0.0 1.3e-91 307.3 0.0 7.2 8 1 0 8 8 8 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 OAJ29859.1 - 2.3e-88 297.0 1.7 2.3e-88 297.0 1.7 4.8 6 1 0 6 6 6 1 Domain of Unknown Function (DUF908) UBM PF14377.6 OAJ29859.1 - 1.1e-19 69.2 12.0 2.4e-11 42.7 0.6 4.0 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 OAJ29859.1 - 1.7e-09 37.4 0.1 4.9e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Oxysterol_BP PF01237.18 OAJ29861.1 - 7e-68 229.1 0.5 1.7e-57 195.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF2673 PF10880.8 OAJ29862.1 - 0.038 14.1 0.1 0.039 14.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) Cloacin PF03515.14 OAJ29862.1 - 0.22 11.2 0.2 0.27 10.9 0.2 1.1 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain IGPD PF00475.18 OAJ29863.1 - 3.6e-60 202.5 0.8 4.9e-60 202.0 0.3 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase FSH1 PF03959.13 OAJ29864.1 - 5.3e-54 183.1 0.0 6.1e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 OAJ29864.1 - 0.028 14.0 0.2 0.059 12.9 0.2 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 OAJ29864.1 - 0.087 12.6 0.1 0.76 9.5 0.1 2.0 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 OAJ29864.1 - 0.15 12.0 0.0 6.5 6.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 OAJ29864.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Mcl1_mid PF12341.8 OAJ29865.1 - 1.7e-72 244.3 0.0 2.8e-71 240.3 0.0 2.3 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 OAJ29865.1 - 2.7e-12 47.0 4.2 0.0025 18.6 0.0 5.7 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ29865.1 - 7.5e-06 26.2 0.0 0.1 12.9 0.0 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 OAJ29865.1 - 0.19 11.7 0.0 0.64 10.1 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Bromodomain PF00439.25 OAJ29866.1 - 2.4e-18 66.0 0.0 4.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Ferrochelatase PF00762.19 OAJ29867.1 - 4.7e-107 357.7 0.0 5.7e-107 357.5 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 OAJ29867.1 - 0.0015 18.8 0.0 0.32 11.4 0.0 2.4 2 0 0 2 2 2 2 CbiX Piwi PF02171.17 OAJ29868.1 - 4.1e-78 262.7 0.0 5.9e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 OAJ29868.1 - 1.5e-15 58.0 0.0 3.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAJ29868.1 - 1e-14 53.9 0.0 2.8e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 OAJ29868.1 - 1.8e-12 47.4 0.1 4.9e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 OAJ29868.1 - 3.2e-12 46.5 0.0 7.8e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 OAJ29868.1 - 1.3e-10 41.2 0.0 2.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain BC10 PF06726.12 OAJ29869.1 - 1.2e-11 44.7 9.2 2.1e-11 43.8 9.2 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 FlxA PF14282.6 OAJ29869.1 - 0.031 14.3 10.0 0.068 13.2 10.0 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF4698 PF15769.5 OAJ29869.1 - 0.047 12.7 3.5 0.084 11.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) SKA1 PF07160.12 OAJ29869.1 - 1 9.1 5.4 2 8.2 5.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DASH_Spc19 PF08287.11 OAJ29869.1 - 4.1 7.3 10.3 7.9 6.3 10.3 1.4 1 0 0 1 1 1 0 Spc19 Malic_M PF03949.15 OAJ29870.1 - 1.2e-91 306.5 0.0 1.7e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 OAJ29870.1 - 2e-63 213.5 0.0 3.6e-63 212.6 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Adeno_shaft PF00608.17 OAJ29871.1 - 0.061 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Peptidase_A22B PF04258.13 OAJ29873.1 - 1.2e-77 261.3 4.9 1.7e-77 260.7 4.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 OAJ29873.1 - 4e-07 29.8 3.8 7.6e-07 28.9 3.8 1.5 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease CENP-B_dimeris PF09026.10 OAJ29873.1 - 0.00091 19.6 0.3 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.6 OAJ29873.1 - 0.015 15.0 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 FAM176 family zf-C2H2 PF00096.26 OAJ29874.1 - 6.3e-10 39.0 7.7 0.00019 21.7 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ29874.1 - 4e-06 27.0 0.7 4e-06 27.0 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ29874.1 - 7.6e-06 26.3 7.4 0.001 19.7 0.5 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ29874.1 - 1.3e-05 25.3 3.4 0.1 12.9 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 OAJ29874.1 - 0.16 12.5 6.2 0.14 12.7 0.7 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RRM_1 PF00076.22 OAJ29875.1 - 7.7e-13 48.1 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 OAJ29875.1 - 1.2e-07 32.2 3.6 1.2e-07 32.2 3.6 2.9 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Methyltransf_23 PF13489.6 OAJ29876.1 - 1e-09 38.4 0.0 2.5e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ29876.1 - 4.8e-08 33.6 0.0 1.3e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ29876.1 - 5e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ29876.1 - 0.0033 18.1 0.0 0.0066 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ29876.1 - 0.0056 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Sacchrp_dh_NADP PF03435.18 OAJ29876.1 - 0.13 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Suf PF05843.14 OAJ29877.1 - 1.7e-82 277.7 0.3 8.1e-79 265.7 0.0 4.2 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 OAJ29877.1 - 1.9e-06 28.2 8.0 7.4 7.7 0.0 8.4 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ29877.1 - 2.2e-05 24.9 0.0 0.54 10.8 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat AKAP95 PF04988.12 OAJ29878.1 - 0.072 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) CDC37_N PF03234.14 OAJ29878.1 - 1.9 9.4 5.5 1.3 9.9 3.1 1.8 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding FAM176 PF14851.6 OAJ29879.1 - 0.068 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 OAJ29879.1 - 0.12 12.8 7.1 0.19 12.1 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFB6 PF17110.5 OAJ29879.1 - 0.24 11.1 1.7 0.39 10.4 1.7 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PBP1_TM PF14812.6 OAJ29879.1 - 0.67 10.4 9.0 1.2 9.6 9.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.9 OAJ29879.1 - 1.2 8.2 11.8 1.7 7.7 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAJ29879.1 - 3.3 5.7 6.6 3.6 5.6 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ29879.1 - 4.3 6.6 11.3 5.9 6.1 11.3 1.1 1 0 0 1 1 1 0 NOA36 protein SDH_alpha PF03313.15 OAJ29880.1 - 3.9e-100 334.8 1.5 5.2e-100 334.4 1.5 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 OAJ29880.1 - 1.7e-55 187.7 0.1 6.7e-55 185.7 0.0 2.0 3 0 0 3 3 3 1 Serine dehydratase beta chain HEAT PF02985.22 OAJ29881.1 - 3.2e-13 48.7 12.8 0.014 15.6 0.0 9.7 8 1 2 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 OAJ29881.1 - 6.9e-10 39.2 16.0 9.1e-06 26.0 0.1 5.8 5 2 0 5 5 5 3 HEAT repeats Cnd1 PF12717.7 OAJ29881.1 - 1.9e-05 24.7 3.2 0.036 14.1 0.0 4.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ29881.1 - 0.0031 16.2 3.6 0.089 11.3 0.0 2.8 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 OAJ29881.1 - 0.16 12.5 1.7 4.8 7.8 0.1 4.2 5 0 0 5 5 5 0 HEAT-like repeat Atg8 PF02991.16 OAJ29882.1 - 4.3e-52 174.7 0.2 5e-52 174.4 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 OAJ29882.1 - 6.3e-07 29.7 0.0 7.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 NAPRTase PF04095.16 OAJ29883.1 - 2.7e-43 148.3 0.0 6.2e-33 114.4 0.0 3.3 2 1 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 OAJ29883.1 - 3.1e-31 108.4 0.1 4.5e-31 107.8 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Mt_ATP-synt_D PF05873.12 OAJ29884.1 - 1.2e-13 51.2 0.3 1.6e-13 50.8 0.3 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HsbA PF12296.8 OAJ29884.1 - 0.0028 18.0 0.9 0.035 14.5 0.2 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1366 PF07104.11 OAJ29884.1 - 0.012 15.3 1.5 0.02 14.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) MiaE_2 PF13794.6 OAJ29884.1 - 0.015 15.0 0.2 0.027 14.2 0.2 1.4 1 1 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like RPW8 PF05659.11 OAJ29884.1 - 0.016 14.9 1.4 0.21 11.3 0.5 2.6 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMPIT PF07851.13 OAJ29884.1 - 0.038 13.2 1.0 0.047 12.9 1.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Glyco_hydro_36N PF16875.5 OAJ29884.1 - 0.041 13.5 0.1 0.067 12.7 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain Phage_GP20 PF06810.11 OAJ29884.1 - 0.041 13.7 5.9 0.22 11.3 6.1 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 SUB1_ProdP9 PF18213.1 OAJ29884.1 - 0.06 13.2 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 Cauli_AT PF03233.13 OAJ29884.1 - 0.11 12.4 1.3 0.19 11.6 1.3 1.4 1 0 0 1 1 1 0 Aphid transmission protein DUF2408 PF10303.9 OAJ29884.1 - 0.16 12.5 1.6 0.28 11.7 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Peptidase_M17_N PF02789.17 OAJ29884.1 - 0.18 11.7 0.2 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain MbeB_N PF04837.12 OAJ29884.1 - 0.31 11.4 3.3 0.2 12.0 0.9 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Pribosyltran PF00156.27 OAJ29885.1 - 0.00058 19.4 0.2 0.0042 16.6 0.2 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF3106 PF11304.8 OAJ29886.1 - 0.57 10.7 6.7 0.94 10.0 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Cys_Met_Meta_PP PF01053.20 OAJ29887.1 - 9.2e-120 399.7 0.0 4.1e-119 397.5 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 OAJ29887.1 - 6.7e-13 48.7 2.0 6.7e-13 48.7 2.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 OAJ29887.1 - 0.00012 22.4 0.4 0.0018 18.6 0.2 3.0 1 1 1 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 OAJ29887.1 - 0.00085 18.8 0.5 0.002 17.7 0.5 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 OAJ29887.1 - 0.081 12.1 0.5 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class I and II SPT16 PF08644.11 OAJ29888.1 - 2e-51 174.1 0.1 7.7e-51 172.2 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 OAJ29888.1 - 4.4e-44 150.1 1.1 1.2e-43 148.7 1.1 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 OAJ29888.1 - 1e-25 90.7 0.0 1.9e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 OAJ29888.1 - 2.1e-15 56.9 0.1 7.2e-15 55.2 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 OAJ29888.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) FlaG PF03646.15 OAJ29889.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 FlaG protein DUF724 PF05266.14 OAJ29890.1 - 0.031 14.1 6.8 0.044 13.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) T2SSM PF04612.12 OAJ29890.1 - 0.23 11.5 6.3 0.43 10.6 6.3 1.5 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M PFL-like PF02901.15 OAJ29890.1 - 0.51 8.9 7.1 0.64 8.6 7.1 1.0 1 0 0 1 1 1 0 Pyruvate formate lyase-like THOC7 PF05615.13 OAJ29890.1 - 0.58 10.4 10.9 1.4 9.2 10.2 1.9 1 1 1 2 2 2 0 Tho complex subunit 7 IBN_N PF03810.19 OAJ29891.1 - 1.5e-13 50.4 0.0 1.5e-12 47.2 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 OAJ29891.1 - 4.1e-08 32.5 0.0 1.1e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 OAJ29891.1 - 2.5e-05 24.4 0.8 0.001 19.1 0.0 2.9 2 1 0 2 2 2 1 Exportin 1-like protein HEAT_2 PF13646.6 OAJ29891.1 - 0.011 16.2 10.7 0.22 12.0 0.0 4.3 5 0 0 5 5 5 0 HEAT repeats HTH_psq PF05225.16 OAJ29891.1 - 0.017 14.9 0.3 0.042 13.6 0.3 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Vac14_Fab1_bd PF12755.7 OAJ29891.1 - 0.034 14.7 0.1 1.6 9.4 0.0 3.8 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region XPC-binding PF09280.11 OAJ29891.1 - 0.073 12.8 0.1 0.35 10.6 0.1 2.2 1 0 0 1 1 1 0 XPC-binding domain AAA PF00004.29 OAJ29892.1 - 1.9e-96 319.5 0.0 4e-47 159.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ29892.1 - 3.4e-25 87.6 8.2 2e-12 46.7 0.4 3.1 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 OAJ29892.1 - 7.9e-21 74.0 0.1 3.1e-20 72.1 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 OAJ29892.1 - 2.1e-14 53.6 0.0 2.1e-05 24.4 0.0 3.7 3 2 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 OAJ29892.1 - 5.5e-13 49.4 0.0 4.2e-07 30.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ29892.1 - 4.2e-12 46.4 0.0 4.7e-06 26.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ29892.1 - 2.9e-11 43.5 0.4 2.6e-05 24.2 0.1 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 OAJ29892.1 - 1.6e-10 40.6 0.0 3.5e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 OAJ29892.1 - 5.2e-10 40.0 0.4 0.0018 18.6 0.0 4.3 3 2 0 3 3 2 2 AAA ATPase domain Vps4_C PF09336.10 OAJ29892.1 - 1.2e-09 38.0 0.4 1e-08 35.0 0.1 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 OAJ29892.1 - 2.6e-09 36.8 0.0 0.0017 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 OAJ29892.1 - 7.4e-09 36.0 0.1 0.021 15.1 0.0 3.9 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 OAJ29892.1 - 4.6e-08 32.7 0.4 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ29892.1 - 3.9e-07 30.0 0.0 0.018 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 OAJ29892.1 - 6.6e-07 29.9 0.0 0.011 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 OAJ29892.1 - 1.2e-06 28.6 0.0 0.022 14.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 OAJ29892.1 - 1.5e-06 28.5 0.0 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 OAJ29892.1 - 1.8e-06 27.6 0.1 0.016 14.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 OAJ29892.1 - 5.1e-06 26.0 0.3 0.96 8.7 0.0 3.4 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 OAJ29892.1 - 6.3e-06 25.5 0.2 0.0064 15.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ29892.1 - 8.3e-06 25.5 0.8 0.19 11.3 0.0 3.7 3 1 1 4 4 3 1 AAA domain AAA_28 PF13521.6 OAJ29892.1 - 9e-06 26.0 0.0 0.085 13.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 OAJ29892.1 - 1.3e-05 24.5 0.0 0.0032 16.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 OAJ29892.1 - 1.9e-05 25.2 0.0 0.14 12.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 OAJ29892.1 - 1.9e-05 24.4 0.0 0.36 10.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 OAJ29892.1 - 3.4e-05 23.7 0.2 0.18 11.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 OAJ29892.1 - 8e-05 23.1 0.1 0.91 9.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 OAJ29892.1 - 0.0001 21.8 0.2 0.41 10.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.18 OAJ29892.1 - 0.00011 22.2 0.0 0.72 9.6 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 OAJ29892.1 - 0.00017 21.6 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 OAJ29892.1 - 0.00018 21.6 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 OAJ29892.1 - 0.00022 21.1 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ29892.1 - 0.00059 19.8 0.3 0.15 12.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 OAJ29892.1 - 0.00067 19.5 0.4 1.2 8.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 OAJ29892.1 - 0.00095 19.0 0.0 0.16 11.7 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 OAJ29892.1 - 0.0012 18.2 0.0 1.3 8.2 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 OAJ29892.1 - 0.0015 18.2 0.7 1.5 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 OAJ29892.1 - 0.0022 18.1 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 OAJ29892.1 - 0.0022 18.0 0.1 3.1 7.6 0.0 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 OAJ29892.1 - 0.0023 18.3 1.7 2.3 8.6 0.0 3.7 3 1 1 4 4 3 1 AAA domain DUF2075 PF09848.9 OAJ29892.1 - 0.0047 16.2 1.8 1.2 8.3 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 OAJ29892.1 - 0.0066 15.7 0.0 0.6 9.3 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain UFD1 PF03152.14 OAJ29892.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 OAJ29892.1 - 0.018 15.0 0.4 2.6 8.0 0.0 3.4 3 0 0 3 3 3 0 NTPase IPT PF01745.16 OAJ29892.1 - 0.025 13.9 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 OAJ29892.1 - 0.036 13.8 0.3 4.7 6.9 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase AFG1_ATPase PF03969.16 OAJ29892.1 - 0.042 12.7 0.0 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase Molydop_binding PF01568.21 OAJ29892.1 - 0.047 13.7 0.1 0.69 10.0 0.0 2.7 2 1 1 3 3 2 0 Molydopterin dinucleotide binding domain T2SSE PF00437.20 OAJ29892.1 - 0.054 12.5 0.0 0.87 8.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 OAJ29892.1 - 0.063 12.5 0.0 0.66 9.2 0.0 2.4 2 1 0 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 OAJ29892.1 - 0.23 10.4 0.1 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Hydin_ADK PF17213.3 OAJ29892.1 - 1.1 9.5 2.8 43 4.3 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Pinin_SDK_memA PF04696.13 OAJ29893.1 - 9.5e-11 41.9 6.0 9.5e-11 41.9 6.0 3.6 3 1 1 4 4 4 2 pinin/SDK/memA/ protein conserved region DUF4407 PF14362.6 OAJ29893.1 - 0.55 9.5 18.1 0.83 9.0 11.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ZapB PF06005.12 OAJ29893.1 - 0.72 10.3 9.7 1 9.8 2.1 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 OAJ29894.1 - 8e-39 133.6 0.0 1.7e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29894.1 - 6e-10 38.8 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinetochor_Ybp2 PF08568.10 OAJ29894.1 - 4.2e-09 35.4 0.0 2.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin APH PF01636.23 OAJ29894.1 - 2.4e-05 24.4 0.0 9e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 OAJ29894.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 OAJ29894.1 - 0.017 14.5 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C PF00481.21 OAJ29895.1 - 5e-83 278.7 0.0 1e-82 277.7 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SNF2_N PF00176.23 OAJ29897.1 - 1.5e-57 194.9 15.8 3.9e-56 190.3 10.4 3.7 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ29897.1 - 3.6e-15 56.3 0.0 7.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1289 PF06945.13 OAJ29897.1 - 0.13 12.1 0.2 0.36 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Trypan_PARP PF05887.11 OAJ29897.1 - 9.1 6.3 14.5 7.7 6.5 0.8 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cu-oxidase_3 PF07732.15 OAJ29898.1 - 5.7e-37 126.4 10.2 9.1e-36 122.5 3.4 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ29898.1 - 7.5e-35 119.7 7.1 1.7e-30 105.6 0.1 3.7 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 OAJ29898.1 - 4.5e-24 85.4 0.0 1.1e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase DUF5060 PF16586.5 OAJ29898.1 - 0.016 15.5 0.1 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) MFS_1 PF07690.16 OAJ29899.1 - 6.1e-29 101.0 31.0 7.9e-29 100.7 31.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 OAJ29899.1 - 1.9 7.2 13.6 0.41 9.4 8.4 1.9 1 1 1 2 2 2 0 MFS_1 like family Cu-oxidase_3 PF07732.15 OAJ29900.1 - 6.6e-38 129.4 2.7 6.6e-38 129.4 2.7 3.3 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 OAJ29900.1 - 2.9e-35 121.0 8.8 5.2e-33 113.7 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ29900.1 - 5.5e-30 104.6 0.3 4.3e-28 98.4 0.0 2.5 2 0 0 2 2 2 1 Multicopper oxidase N_BRCA1_IG PF16158.5 OAJ29900.1 - 0.0015 19.2 0.0 0.0059 17.3 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PBP1_TM PF14812.6 OAJ29901.1 - 0.028 14.8 7.6 0.028 14.8 7.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 OAJ29901.1 - 0.032 14.0 4.8 0.054 13.2 4.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 OAJ29901.1 - 0.045 13.2 6.3 0.086 12.3 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.14 OAJ29901.1 - 0.17 10.1 0.4 0.2 9.9 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ29901.1 - 0.28 9.3 4.2 0.39 8.8 4.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 OAJ29901.1 - 0.36 10.8 1.9 0.7 9.9 1.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 OAJ29901.1 - 0.45 9.8 9.8 0.023 14.0 4.3 1.6 2 0 0 2 2 2 0 NOA36 protein PGA2 PF07543.12 OAJ29901.1 - 0.77 9.7 4.7 1.6 8.7 4.7 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 GCIP PF13324.6 OAJ29901.1 - 0.85 9.2 3.2 6.6 6.3 2.1 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 OAJ29901.1 - 3.7 8.0 15.0 8.1 6.9 15.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_2 PF07719.17 OAJ29902.1 - 8.6e-16 56.7 26.0 0.013 15.5 0.1 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ29902.1 - 8e-15 54.0 12.5 2.3e-05 24.0 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ29902.1 - 5.1e-10 38.9 0.8 0.039 13.6 0.0 6.3 5 2 2 7 7 7 2 TPR repeat TPR_14 PF13428.6 OAJ29902.1 - 6.7e-10 39.0 39.6 0.021 15.6 0.2 9.9 6 1 4 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ29902.1 - 7.2e-09 36.0 29.8 4.1e-07 30.4 0.6 7.4 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ29902.1 - 1.1e-08 34.8 0.1 0.51 10.8 0.1 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ29902.1 - 1.3e-07 31.3 10.4 0.16 12.2 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ29902.1 - 4.8e-07 30.3 5.7 0.0025 18.4 0.3 8.1 6 1 4 10 10 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ29902.1 - 3.5e-05 24.0 25.1 0.012 15.9 1.1 6.5 4 2 3 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ29902.1 - 0.0002 21.5 6.7 2.3 8.5 0.0 4.9 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 OAJ29902.1 - 0.0013 18.9 0.8 0.0013 18.9 0.8 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ29902.1 - 0.017 15.1 15.4 0.69 10.1 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat CDC45 PF02724.14 OAJ29902.1 - 0.041 12.2 21.2 0.077 11.3 21.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ29902.1 - 0.14 10.4 27.5 0.2 9.8 27.5 1.1 1 0 0 1 1 1 0 Nop14-like family SNAP PF14938.6 OAJ29902.1 - 1.3 8.4 7.0 4.3 6.7 1.7 3.0 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP DUF2457 PF10446.9 OAJ29902.1 - 1.6 7.8 33.8 4.1 6.4 33.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.10 OAJ29902.1 - 1.8 8.8 7.7 4.8 7.5 7.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.12 OAJ29902.1 - 2.6 7.4 32.1 5.3 6.4 32.1 1.4 1 0 0 1 1 1 0 SDA1 Glyco_hydro_35 PF01301.19 OAJ29903.1 - 5e-74 249.8 0.0 8.8e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 OAJ29903.1 - 9.9e-40 135.7 0.1 9.1e-25 87.5 0.0 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 OAJ29903.1 - 9.6e-25 87.4 0.0 1.6e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 OAJ29903.1 - 1.1e-07 31.3 0.0 2.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 OAJ29903.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PPR_2 PF13041.6 OAJ29904.1 - 0.00011 22.3 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family FTA4 PF13093.6 OAJ29904.1 - 0.018 15.0 0.9 0.039 13.8 0.9 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PPR_3 PF13812.6 OAJ29904.1 - 0.14 12.2 0.2 1.9 8.6 0.1 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain CAP_N PF01213.19 OAJ29904.1 - 3.5 7.0 8.6 7.1 6.0 0.4 3.5 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Nop PF01798.18 OAJ29905.1 - 2e-83 279.4 0.1 2e-83 279.4 0.1 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 OAJ29905.1 - 1.1e-16 60.9 0.0 6.4e-16 58.5 0.0 2.4 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Sporozoite_P67 PF05642.11 OAJ29905.1 - 0.024 12.7 12.1 0.035 12.2 12.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 OAJ29905.1 - 1.2 7.4 27.3 1.7 6.9 27.3 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 OAJ29905.1 - 1.9 8.5 32.1 3.4 7.7 32.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Spt5_N PF11942.8 OAJ29905.1 - 4 8.5 22.4 8.4 7.5 22.4 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SGT1 PF07093.11 OAJ29905.1 - 4.3 5.7 15.8 6.2 5.1 15.8 1.3 1 0 0 1 1 1 0 SGT1 protein Neur_chan_memb PF02932.16 OAJ29905.1 - 8.3 6.4 9.6 12 5.9 9.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ZZ PF00569.17 OAJ29906.1 - 5.7e-22 77.3 62.2 9e-08 31.8 2.6 6.1 6 0 0 6 6 6 4 Zinc finger, ZZ type N_BRCA1_IG PF16158.5 OAJ29906.1 - 2.1e-20 73.3 0.5 9.2e-20 71.3 0.0 2.5 3 0 0 3 3 3 1 Ig-like domain from next to BRCA1 gene C1_2 PF03107.16 OAJ29906.1 - 0.00025 21.3 2.2 0.00025 21.3 2.2 5.9 6 0 0 6 6 6 2 C1 domain DUF2478 PF10649.9 OAJ29906.1 - 0.0032 17.1 0.4 0.0088 15.7 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) AAA_32 PF13654.6 OAJ29906.1 - 0.064 12.0 0.1 7.1 5.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_S64 PF08192.11 OAJ29906.1 - 0.27 9.7 6.5 0.46 8.9 6.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 PIG-U PF06728.13 OAJ29907.1 - 8.6e-71 239.0 9.1 1.1e-70 238.7 9.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 OAJ29907.1 - 7.1e-05 22.8 0.6 0.0005 20.0 0.6 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) DEAD PF00270.29 OAJ29908.1 - 1.5e-31 109.6 0.0 1.8e-30 106.0 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ29908.1 - 1.1e-15 57.9 0.1 8.9e-15 55.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ29908.1 - 0.01 15.8 0.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NADH_B2 PF14813.6 OAJ29909.1 - 0.0013 18.5 0.6 0.0016 18.2 0.6 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 VWA PF00092.28 OAJ29911.1 - 1.6e-06 28.5 0.0 7.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 OAJ29911.1 - 1.9e-05 25.2 0.0 7.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain MC1 PF05854.11 OAJ29911.1 - 0.08 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Ribosomal_S16 PF00886.19 OAJ29912.1 - 3.5e-25 87.8 0.0 9.8e-25 86.4 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 OAJ29913.1 - 9.8e-32 108.6 0.0 3.8e-12 45.9 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ29913.1 - 0.00011 22.1 0.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ29913.1 - 0.00051 20.1 0.0 1.3 9.1 0.0 4.7 5 0 0 5 5 5 1 RNA recognition motif Nup35_RRM PF05172.13 OAJ29913.1 - 0.00098 19.1 0.0 0.013 15.4 0.0 2.6 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 OAJ29913.1 - 0.038 13.6 0.0 0.54 9.9 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_14 PF13428.6 OAJ29913.1 - 0.18 12.7 1.6 1.6 9.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ATP_bind_1 PF03029.17 OAJ29914.1 - 8.2e-69 232.0 0.0 2.7e-64 217.2 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein SRP54 PF00448.22 OAJ29914.1 - 0.0018 18.0 0.4 0.013 15.1 0.2 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 OAJ29914.1 - 0.0022 18.0 0.0 0.043 13.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ29914.1 - 0.0065 16.0 0.0 0.57 9.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAJ29914.1 - 0.0068 16.7 0.2 0.02 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAJ29914.1 - 0.009 15.7 0.3 0.054 13.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 OAJ29914.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 OAJ29914.1 - 0.019 15.1 0.2 0.019 15.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 OAJ29914.1 - 0.023 14.6 0.0 3.9 7.3 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 OAJ29914.1 - 0.037 14.4 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 OAJ29914.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 OAJ29914.1 - 0.045 12.7 0.1 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 OAJ29914.1 - 0.075 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 OAJ29914.1 - 0.13 11.8 0.0 17 4.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 OAJ29914.1 - 0.15 11.8 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ29914.1 - 0.23 12.0 0.2 0.23 12.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 OAJ29914.1 - 4 7.5 6.3 0.56 10.3 0.4 2.2 2 1 0 2 2 2 0 Helicase HerA, central domain Thiolase_N PF00108.23 OAJ29915.1 - 8.2e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ29915.1 - 4e-41 139.5 0.6 1.2e-40 137.9 0.4 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ29915.1 - 0.0017 18.0 0.7 0.025 14.1 0.7 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ29915.1 - 0.0045 16.8 1.3 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 OAJ29915.1 - 0.006 16.7 0.1 0.019 15.1 0.1 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF4504 PF14953.6 OAJ29916.1 - 1.8e-06 27.6 0.1 0.0022 17.4 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4504) FAD_binding_4 PF01565.23 OAJ29917.1 - 1e-22 80.4 1.5 1.8e-22 79.6 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ29917.1 - 0.0048 17.0 0.2 0.01 15.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like PIN_4 PF13638.6 OAJ29918.1 - 7.7e-10 39.2 0.0 1.1e-09 38.7 0.0 1.5 1 1 0 1 1 1 1 PIN domain Mit_KHE1 PF10173.9 OAJ29919.1 - 9e-55 185.7 0.3 1.3e-54 185.2 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Histone_H2A_C PF16211.5 OAJ29920.1 - 1.6e-14 53.4 0.3 2.4e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ29920.1 - 2.8e-09 37.4 0.0 4.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Exo_endo_phos PF03372.23 OAJ29921.1 - 5.4e-07 29.4 0.0 1.2e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 OAJ29922.1 - 1.7e-35 122.6 39.6 3.1e-35 121.8 38.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ29922.1 - 1e-11 44.4 20.2 2.4e-11 43.2 9.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAJ29922.1 - 1e-06 27.5 13.1 5.7e-05 21.7 8.1 2.8 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Endomucin PF07010.12 OAJ29923.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.4 3 1 1 4 4 4 0 Endomucin Sporozoite_P67 PF05642.11 OAJ29924.1 - 0.54 8.3 3.0 0.79 7.7 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 OAJ29924.1 - 2.2 7.4 6.7 3.3 6.8 6.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn60_TCP1 PF00118.24 OAJ29925.1 - 3.1e-159 530.7 4.8 3.5e-159 530.5 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 OAJ29925.1 - 0.028 13.6 0.4 0.24 10.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 OAJ29926.1 - 7.3e-50 169.8 0.0 1.3e-49 169.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 OAJ29926.1 - 1.6e-11 44.4 0.4 3.7e-11 43.2 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 OAJ29926.1 - 1.4e-10 40.5 1.8 0.00014 21.5 0.1 5.9 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.13 OAJ29926.1 - 0.044 12.6 0.0 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AMP-binding_C PF13193.6 OAJ29926.1 - 0.05 14.6 4.5 0.13 13.2 0.0 3.3 4 0 0 4 4 4 0 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 OAJ29926.1 - 0.31 10.8 10.0 2.4 8.0 0.1 4.6 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase DnaJ PF00226.31 OAJ29927.1 - 5.5e-23 80.9 0.2 9.7e-23 80.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 OAJ29927.1 - 1.6e-19 70.1 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Pap_E4 PF02711.14 OAJ29928.1 - 7.3 7.6 11.9 18 6.3 11.1 2.1 1 1 0 1 1 1 0 E4 protein ABC_tran PF00005.27 OAJ29929.1 - 1.9e-15 57.6 0.1 2.4e-13 50.8 0.0 3.3 2 2 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 OAJ29929.1 - 1.5e-08 34.9 7.1 0.01 15.6 0.3 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 OAJ29929.1 - 3.9e-06 27.0 0.0 0.037 14.3 0.0 2.9 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 OAJ29929.1 - 0.00031 21.3 0.1 0.00057 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ29929.1 - 0.003 17.2 0.1 0.0063 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ29929.1 - 0.0044 16.8 0.0 0.0064 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 OAJ29929.1 - 0.0053 16.3 1.3 0.2 11.2 0.1 2.6 3 0 0 3 3 3 1 AAA domain SRPRB PF09439.10 OAJ29929.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit SMC_N PF02463.19 OAJ29929.1 - 0.031 13.7 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.21 OAJ29929.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_24 PF13479.6 OAJ29929.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 OAJ29929.1 - 0.15 11.1 1.2 0.22 10.6 0.0 1.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_7 PF12775.7 OAJ29929.1 - 0.25 10.8 0.0 1.1 8.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AMPKBI PF04739.15 OAJ29930.1 - 1e-26 92.9 0.1 2.6e-26 91.7 0.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 OAJ29930.1 - 1.8e-26 92.2 0.0 3.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 OAJ29930.1 - 0.0051 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MF_alpha_N PF05436.11 OAJ29932.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus OAD_gamma PF04277.13 OAJ29933.1 - 0.2 12.3 1.2 0.73 10.5 0.2 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain VIR_N PF15912.5 OAJ29933.1 - 1.6 8.3 7.0 1.6 8.3 5.8 1.5 1 1 0 1 1 1 0 Virilizer, N-terminal DUF3712 PF12505.8 OAJ29934.1 - 4.6e-109 359.7 42.7 1.1e-23 83.9 0.0 10.3 10 0 0 10 10 10 8 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ29934.1 - 0.00048 20.6 19.2 0.19 12.3 0.1 7.5 8 0 0 8 8 8 3 Late embryogenesis abundant protein Cyclin_N PF00134.23 OAJ29935.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 OAJ29935.1 - 0.00019 21.8 0.2 0.00019 21.8 0.2 2.6 2 1 0 2 2 2 1 Cyclin TPR_1 PF00515.28 OAJ29936.1 - 5.3e-22 76.7 0.5 6.2e-08 32.1 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ29936.1 - 1.9e-21 74.4 7.1 4e-06 26.5 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ29936.1 - 7.4e-14 51.3 8.3 0.00016 22.2 0.1 5.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ29936.1 - 2e-13 49.4 1.7 0.0074 16.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ29936.1 - 6.9e-12 44.9 8.8 0.00053 19.6 0.1 5.0 3 1 2 5 5 5 3 TPR repeat TPR_19 PF14559.6 OAJ29936.1 - 1.8e-10 41.2 6.6 0.0015 19.0 0.2 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ29936.1 - 2.1e-09 37.9 7.0 1.5e-05 25.5 0.3 4.6 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ29936.1 - 8.1e-09 35.3 2.6 0.00045 20.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ29936.1 - 2.5e-08 34.1 8.0 0.0032 17.7 2.8 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ29936.1 - 0.0001 22.7 9.1 5.4 7.9 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ29936.1 - 0.00015 21.5 7.7 0.26 11.4 0.0 4.4 6 0 0 6 6 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ29936.1 - 0.00025 21.3 2.3 0.9 9.9 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ29936.1 - 0.0091 16.1 5.0 0.034 14.3 0.2 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 OAJ29936.1 - 0.0096 16.4 11.1 0.86 10.0 1.7 4.1 4 0 0 4 4 4 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 OAJ29936.1 - 0.015 15.5 3.6 0.018 15.3 0.4 2.6 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 OAJ29936.1 - 0.031 13.5 3.9 2.9 7.0 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 OAJ29936.1 - 0.1 12.6 0.5 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ29936.1 - 0.17 11.8 12.8 0.69 9.9 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 OAJ29936.1 - 0.74 9.7 4.9 4.5 7.2 0.1 3.2 2 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CSRNP_N PF16019.5 OAJ29936.1 - 2.8 7.8 5.7 0.19 11.6 0.4 1.6 2 0 0 2 2 1 0 Cysteine/serine-rich nuclear protein N-terminus ATG13 PF10033.9 OAJ29937.1 - 1.7e-35 122.9 0.0 2.4e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 Nuc_sug_transp PF04142.15 OAJ29938.1 - 5.4e-66 222.9 6.7 3.3e-49 167.8 1.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 OAJ29938.1 - 0.0012 19.0 8.0 0.0012 19.0 8.0 3.7 2 2 1 3 3 3 1 EamA-like transporter family DUF3439 PF11921.8 OAJ29938.1 - 0.0093 15.9 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) CRT-like PF08627.10 OAJ29938.1 - 0.3 10.0 4.4 0.12 11.3 1.0 1.8 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like OSCP PF00213.18 OAJ29939.1 - 6.4e-39 133.8 0.7 7.7e-39 133.6 0.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PALP PF00291.25 OAJ29940.1 - 9.1e-68 228.8 0.1 1.3e-67 228.3 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CCCH_2 PF14608.6 OAJ29941.1 - 9.1e-13 48.2 37.6 0.00053 20.4 3.8 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger GYF PF02213.16 OAJ29942.1 - 0.0066 16.1 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 GYF domain Roughex PF06020.11 OAJ29943.1 - 0.15 11.1 1.2 0.24 10.5 1.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Sigma70_ner PF04546.13 OAJ29943.1 - 5.5 6.8 8.6 12 5.7 8.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region ABC_tran PF00005.27 OAJ29944.1 - 2.1e-42 144.9 0.0 7.9e-24 84.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ29944.1 - 4.1e-41 141.4 29.3 1.8e-23 83.6 5.6 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 OAJ29944.1 - 2e-09 37.2 0.0 6.1e-05 22.6 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 OAJ29944.1 - 1.3e-05 25.5 0.3 0.024 14.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ29944.1 - 0.00044 19.9 0.0 0.56 9.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 OAJ29944.1 - 0.00085 18.5 0.1 0.3 10.1 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ29944.1 - 0.0014 18.3 1.4 0.15 11.9 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain ATPase PF06745.13 OAJ29944.1 - 0.02 14.3 0.2 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 KaiC TrwB_AAD_bind PF10412.9 OAJ29944.1 - 0.063 12.2 0.1 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 OAJ29944.1 - 0.073 12.7 0.7 0.42 10.2 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 OAJ29944.1 - 0.075 12.8 0.4 18 5.1 0.0 3.1 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 OAJ29944.1 - 0.077 12.7 0.1 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 OAJ29944.1 - 0.14 11.6 0.2 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 OAJ29944.1 - 0.14 11.6 0.0 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 OAJ29944.1 - 0.16 11.7 1.7 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_16 PF13191.6 OAJ29944.1 - 0.43 10.9 10.1 0.82 10.0 3.3 3.6 3 1 0 3 3 2 0 AAA ATPase domain AAA_23 PF13476.6 OAJ29944.1 - 0.78 10.2 9.4 1.9 8.9 0.1 3.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 OAJ29944.1 - 1.1 9.3 3.9 0.25 11.4 0.1 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain ParA PF10609.9 OAJ29945.1 - 4.6e-80 268.6 0.1 3.3e-42 144.7 0.0 3.0 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 OAJ29945.1 - 8.4e-06 25.9 0.5 0.00068 19.7 0.3 2.8 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 OAJ29945.1 - 0.00073 18.8 0.2 0.0014 17.8 0.2 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase SelB-wing_3 PF09107.11 OAJ29945.1 - 0.015 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix RsgA_GTPase PF03193.16 OAJ29945.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_31 PF13614.6 OAJ29945.1 - 0.027 14.4 0.3 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 OAJ29945.1 - 0.055 12.9 0.0 6.1 6.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 OAJ29945.1 - 0.058 13.0 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ29945.1 - 0.062 12.5 0.0 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 OAJ29945.1 - 0.072 13.5 0.0 0.66 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 OAJ29945.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_26 PF13500.6 OAJ29945.1 - 0.12 12.2 0.0 0.91 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF4611 PF15387.6 OAJ29945.1 - 1.7 8.9 5.5 3.6 7.9 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) MIP PF00230.20 OAJ29946.1 - 2.6e-45 154.9 6.2 3.6e-45 154.4 6.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein TubC_N PF18563.1 OAJ29947.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 TubC N-terminal docking domain COX15-CtaA PF02628.15 OAJ29948.1 - 3e-88 296.0 13.5 2.9e-86 289.5 13.5 3.3 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein NCBP3 PF10309.9 OAJ29949.1 - 2.7e-11 43.1 0.0 4.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 BRO1 PF03097.18 OAJ29950.1 - 3.8e-109 365.1 0.1 7.5e-109 364.1 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ29950.1 - 7.2e-48 163.4 9.5 1.3e-47 162.5 9.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV NOT2_3_5 PF04153.18 OAJ29951.1 - 1.2e-33 116.0 2.6 2.1e-33 115.2 2.6 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Tektin PF03148.14 OAJ29951.1 - 0.24 10.1 2.1 0.32 9.7 2.1 1.1 1 0 0 1 1 1 0 Tektin family Robl_LC7 PF03259.17 OAJ29951.1 - 0.83 9.5 0.0 0.83 9.5 0.0 3.1 3 0 0 3 3 3 0 Roadblock/LC7 domain Folliculin PF11704.8 OAJ29951.1 - 2.6 7.9 4.4 1.3 8.8 1.8 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Peptidase_M50 PF02163.22 OAJ29953.1 - 3e-08 33.3 4.6 0.00084 18.7 0.1 2.9 1 1 1 2 2 2 2 Peptidase family M50 Glyco_hydro_88 PF07470.13 OAJ29955.1 - 1.1e-15 57.6 2.4 2.7e-15 56.3 0.2 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.13 OAJ29956.1 - 1.4e-10 40.8 0.8 8.2e-10 38.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 CAP PF00188.26 OAJ29957.1 - 1.2e-18 68.1 1.2 3.2e-18 66.8 1.2 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ABC_membrane PF00664.23 OAJ29958.1 - 9.6e-45 153.3 38.0 1e-28 100.7 16.4 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ29958.1 - 1.7e-40 138.7 0.0 7e-26 91.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ29958.1 - 7.6e-08 32.1 4.6 0.0066 15.9 0.1 4.5 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ29958.1 - 0.00017 22.2 0.0 0.72 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ29958.1 - 0.00039 20.1 0.4 0.8 9.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ29958.1 - 0.0018 18.6 0.9 1.8 8.8 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAJ29958.1 - 0.014 15.5 1.6 0.015 15.4 0.2 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 OAJ29958.1 - 0.025 15.0 0.1 0.26 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 OAJ29958.1 - 0.026 14.5 0.6 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_24 PF13479.6 OAJ29958.1 - 0.035 13.8 0.3 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ29958.1 - 0.092 12.3 0.4 0.72 9.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAJ29958.1 - 0.11 12.4 0.2 22 4.9 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 OAJ29958.1 - 0.14 12.6 0.2 4.5 7.7 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NDC10_II PF16787.5 OAJ29959.1 - 8.6e-08 31.6 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 CDC45 PF02724.14 OAJ29960.1 - 0.13 10.5 3.3 0.15 10.3 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ29960.1 - 0.64 8.0 10.8 0.84 7.7 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi HEAT_2 PF13646.6 OAJ29961.1 - 6.7e-20 71.3 4.6 1e-12 48.2 0.4 4.8 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 OAJ29961.1 - 3.1e-12 45.6 2.9 0.063 13.6 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 OAJ29961.1 - 9e-11 41.4 8.4 0.012 16.3 0.0 7.4 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat Arm PF00514.23 OAJ29961.1 - 0.0011 18.9 0.0 0.39 10.8 0.0 2.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 OAJ29961.1 - 1.1 9.8 11.6 1.9 9.1 0.1 4.6 4 2 0 5 5 5 0 HEAT-like repeat PHD PF00628.29 OAJ29962.1 - 2.9e-13 49.5 20.7 1.6e-08 34.3 9.0 2.8 3 0 0 3 3 3 2 PHD-finger DUF1360 PF07098.11 OAJ29962.1 - 0.79 9.7 2.4 1.1 9.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) zf-PHD-like PF15446.6 OAJ29962.1 - 1.5 8.4 5.4 0.41 10.2 2.1 1.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Glyco_transf_28 PF03033.20 OAJ29963.1 - 3.9e-24 85.3 0.0 7.6e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 OAJ29963.1 - 3.9e-05 23.5 0.0 0.12 12.3 0.0 2.9 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.18 OAJ29963.1 - 0.0016 17.3 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 OAJ29963.1 - 0.0039 17.7 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Rod_cone_degen PF15201.6 OAJ29963.1 - 0.9 9.7 4.0 1 9.5 0.4 3.2 2 0 0 2 2 2 0 Progressive rod-cone degeneration Mobilization_B PF17511.2 OAJ29963.1 - 4.1 7.8 5.4 15 5.9 5.4 1.9 1 0 0 1 1 1 0 Mobilization protein B DnaJ_C PF01556.18 OAJ29964.1 - 3.9e-29 101.6 0.1 5.8e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ29964.1 - 2e-21 75.8 5.1 3.1e-21 75.3 5.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 OAJ29964.1 - 9.5e-15 54.7 17.0 1.6e-14 54.0 17.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 OAJ29964.1 - 0.0039 17.2 7.8 0.33 11.0 2.9 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 OAJ29964.1 - 0.0045 16.9 6.4 0.31 11.0 0.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 OAJ29964.1 - 2.5 8.6 11.5 4.3 7.9 4.6 2.2 1 1 1 2 2 2 0 Cytochrome c3 zf-RING_10 PF16685.5 OAJ29964.1 - 4.3 7.5 8.3 0.6 10.3 1.1 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 OAJ29964.1 - 5.8 6.5 11.2 0.3 10.7 0.9 2.5 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 DZR PF12773.7 OAJ29964.1 - 6.5 6.9 8.8 23 5.1 9.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF1924 PF09086.11 OAJ29964.1 - 9.4 6.7 8.0 2.7 8.4 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1924) Ras PF00071.22 OAJ29965.1 - 6.7e-48 162.3 0.0 7.7e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ29965.1 - 8.1e-18 64.8 0.0 1.1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ29965.1 - 2.3e-06 27.1 0.0 2.6e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ29965.1 - 5.9e-05 23.0 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 OAJ29965.1 - 0.00067 19.3 0.1 0.0014 18.2 0.0 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ29965.1 - 0.0016 18.5 0.1 0.0024 17.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ29965.1 - 0.047 13.2 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.16 OAJ29965.1 - 0.059 12.7 0.1 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 AIG1 family AAA_28 PF13521.6 OAJ29965.1 - 0.16 12.2 0.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Usp PF00582.26 OAJ29966.1 - 1.3e-14 55.0 1.1 6.4e-14 52.7 1.1 2.1 1 1 0 1 1 1 1 Universal stress protein family DUF572 PF04502.13 OAJ29966.1 - 0.37 10.4 8.6 1.4 8.5 8.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 OAJ29966.1 - 2.2 7.0 10.8 5.4 5.8 10.8 1.7 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 OAJ29966.1 - 4.9 5.6 9.6 9.3 4.7 9.6 1.4 1 0 0 1 1 1 0 Macoilin family GCP_N_terminal PF17681.1 OAJ29967.1 - 3.8e-89 299.4 0.0 3.6e-88 296.1 0.0 2.4 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 OAJ29967.1 - 2.3e-77 260.5 0.3 1.3e-76 258.1 0.1 2.2 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal Acyl_transf_3 PF01757.22 OAJ29968.1 - 0.00014 21.1 35.2 0.0002 20.6 35.2 1.2 1 0 0 1 1 1 1 Acyltransferase family Phage_holin_5_2 PF16079.5 OAJ29968.1 - 0.056 13.8 0.1 0.27 11.6 0.0 2.2 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V PCIF1_WW PF12237.8 OAJ29968.1 - 0.099 12.3 0.2 0.26 10.9 0.2 1.7 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain TFIIA PF03153.13 OAJ29969.1 - 8.8 6.2 11.7 14 5.5 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAS_9 PF13426.7 OAJ29970.1 - 7.6e-21 74.3 0.0 2.4e-13 50.2 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 OAJ29970.1 - 6.7e-13 48.6 0.6 5.5e-08 32.8 0.0 3.9 4 1 0 4 4 4 2 PAS fold PAS_3 PF08447.12 OAJ29970.1 - 8.5e-13 48.4 0.0 1.3e-06 28.6 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_4 PF08448.10 OAJ29970.1 - 1.3e-06 28.6 0.0 0.0003 21.0 0.0 3.7 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 OAJ29970.1 - 0.00021 21.3 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.6 OAJ29970.1 - 0.04 14.0 0.1 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 PAS domain Tad_C PF09977.9 OAJ29970.1 - 0.7 11.2 8.5 6.8 8.0 0.4 3.2 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly Ammonium_transp PF00909.21 OAJ29972.1 - 1.9e-24 86.1 0.5 2.5e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Ammonium Transporter Family Malate_synthase PF01274.22 OAJ29972.1 - 1.6e-11 43.2 0.1 2.1e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Malate synthase RNA_pol_I_A49 PF06870.12 OAJ29972.1 - 6.7e-09 35.1 0.2 8.3e-09 34.8 0.2 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor YqzM PF14141.6 OAJ29972.1 - 0.018 15.1 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 YqzM-like protein GST_N_3 PF13417.6 OAJ29973.1 - 5.5e-08 33.1 0.0 9.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ29973.1 - 3.4e-07 30.2 1.3 6e-07 29.4 1.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 OAJ29973.1 - 1.5e-06 28.4 0.0 2.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 OAJ29973.1 - 0.006 16.4 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ29973.1 - 0.016 15.4 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 OAJ29973.1 - 0.11 13.3 0.0 0.5 11.1 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain LETM1 PF07766.13 OAJ29974.1 - 1.7e-19 70.2 0.1 1.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 LETM1-like protein RAP1 PF07218.11 OAJ29974.1 - 7.3 4.7 7.7 14 3.8 7.7 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1729 PF08354.10 OAJ29975.1 - 2.2e-157 523.5 0.0 3.3e-157 522.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 OAJ29975.1 - 4.7e-65 220.2 0.4 5.1e-64 216.8 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 OAJ29975.1 - 6.2e-40 136.4 0.0 1.2e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 OAJ29975.1 - 1e-29 104.0 0.0 3.4e-28 99.0 0.0 2.3 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 OAJ29975.1 - 9.5e-27 93.0 0.0 3.2e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAJ29975.1 - 2.7e-07 30.8 0.0 2.3e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAS_I_H PF18314.1 OAJ29976.1 - 8.1e-23 81.1 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 OAJ29976.1 - 2.9e-17 63.5 0.3 6.9e-17 62.3 0.1 1.7 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Pkinase PF00069.25 OAJ29977.1 - 7.1e-63 212.4 0.0 6.3e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ29977.1 - 1.9e-26 92.9 0.0 2.5e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ29977.1 - 0.00036 20.0 0.0 0.00063 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ29977.1 - 0.0035 16.3 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ29977.1 - 0.09 12.7 3.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAM-associated PF14303.6 OAJ29977.1 - 5.5 7.7 7.3 3.1 8.5 4.5 1.8 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain TFIIA PF03153.13 OAJ29977.1 - 7.8 6.4 6.4 12 5.8 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MmgE_PrpD PF03972.14 OAJ29979.1 - 8.3e-10 37.8 0.0 9e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family HSP70 PF00012.20 OAJ29980.1 - 8.8e-51 172.8 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Methyltransf_8 PF05148.15 OAJ29980.1 - 0.00051 20.0 0.0 0.00097 19.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MmgE_PrpD PF03972.14 OAJ29981.1 - 1.1e-90 304.3 0.6 1.4e-90 304.0 0.6 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Methyltransf_25 PF13649.6 OAJ29982.1 - 4.3e-11 43.4 0.1 1e-10 42.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ29982.1 - 1.8e-10 40.8 0.2 3.2e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ29982.1 - 1.9e-10 40.7 0.1 3.2e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 OAJ29982.1 - 1.5e-08 34.7 0.0 4.2e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ29982.1 - 1.3e-07 32.1 0.0 3.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ29982.1 - 4.8e-07 29.4 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 OAJ29982.1 - 1.3e-05 24.3 0.0 1.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 OAJ29982.1 - 7.9e-05 22.3 0.1 0.00016 21.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 OAJ29982.1 - 0.00017 22.2 0.1 0.0004 21.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 OAJ29982.1 - 0.0017 18.3 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 OAJ29982.1 - 0.0018 18.4 0.2 0.0031 17.6 0.2 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 OAJ29982.1 - 0.0042 16.9 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 OAJ29982.1 - 0.0056 16.4 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 OAJ29982.1 - 0.025 13.9 0.3 0.062 12.6 0.1 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 OAJ29982.1 - 0.031 13.7 0.4 0.1 12.0 0.4 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 OAJ29982.1 - 0.05 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 OAJ29982.1 - 0.067 13.2 0.6 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 OAJ29982.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ferric_reduct PF01794.19 OAJ29983.1 - 4e-20 72.2 7.9 4e-20 72.2 7.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ29983.1 - 1.5e-11 44.7 0.0 2.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ29983.1 - 6.8e-07 29.3 0.0 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain DUF92 PF01940.16 OAJ29984.1 - 5.3e-71 238.8 6.9 6.7e-71 238.4 6.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 GerA PF03323.13 OAJ29984.1 - 0.64 8.4 2.0 1 7.8 2.0 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Sulfate_transp PF00916.20 OAJ29985.1 - 8.9e-111 370.3 15.7 1.2e-110 369.9 15.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 OAJ29985.1 - 4.6e-10 39.1 0.0 8.8e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 OAJ29985.1 - 0.027 14.9 19.2 0.037 14.4 3.4 3.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Mucin PF01456.17 OAJ29987.1 - 9.5e-05 22.4 17.3 0.00018 21.5 15.4 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Peptidase_S24 PF00717.23 OAJ29987.1 - 0.088 12.8 0.0 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase S24-like Hexapep PF00132.24 OAJ29988.1 - 3.9e-06 26.4 1.3 0.012 15.3 1.2 2.9 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 OAJ29988.1 - 0.0067 16.8 0.6 0.0067 16.8 0.6 2.7 2 1 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.12 OAJ29988.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 L-fucokinase NTP_transferase PF00483.23 OAJ29988.1 - 0.15 11.6 0.0 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 Nucleotidyl transferase hDGE_amylase PF14701.6 OAJ29989.1 - 1.5e-164 548.3 0.0 2e-164 547.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 OAJ29989.1 - 5.7e-111 371.1 0.0 7.6e-111 370.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 OAJ29989.1 - 6.9e-85 284.7 0.0 1.1e-84 284.0 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 OAJ29989.1 - 9.5e-20 70.5 0.0 2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 OAJ29989.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Mucin PF01456.17 OAJ29989.1 - 8.7 6.3 16.6 19 5.3 16.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Maf1 PF09174.10 OAJ29990.1 - 2e-29 102.9 0.0 6.5e-18 65.5 0.0 3.5 3 0 0 3 3 3 3 Maf1 regulator Sad1_UNC PF07738.13 OAJ29991.1 - 3.3e-13 49.8 0.0 1.5e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Chordopox_A30L PF06015.12 OAJ29991.1 - 0.055 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Atg14 PF10186.9 OAJ29992.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RVT_1 PF00078.27 OAJ29994.1 - 1.3e-29 103.3 0.0 1.9e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 OAJ29994.1 - 1.9e-16 60.0 0.8 5.8e-16 58.4 0.1 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 OAJ29995.1 - 0.036 14.1 2.5 0.036 14.1 2.5 3.0 3 0 0 3 3 3 0 Zinc knuckle VESA1_N PF12785.7 OAJ29995.1 - 0.07 12.1 9.8 0.087 11.8 9.8 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 CLIP1_ZNF PF16641.5 OAJ29995.1 - 0.25 11.3 0.2 0.25 11.3 0.2 3.5 3 1 0 3 3 3 0 CLIP1 zinc knuckle zf-CCHC_6 PF15288.6 OAJ29995.1 - 8.2 6.4 21.6 0.48 10.3 1.4 3.6 3 0 0 3 3 3 0 Zinc knuckle Alg6_Alg8 PF03155.15 OAJ29996.1 - 1.4e-146 489.3 0.0 2.5e-146 488.5 0.0 1.3 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PGM_PMM_I PF02878.16 OAJ29997.1 - 7.6e-22 77.5 0.1 9.3e-12 44.8 0.2 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 OAJ29997.1 - 6.2e-09 35.9 0.2 1.8e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 OAJ29997.1 - 9.6e-05 22.5 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 OAJ29997.1 - 0.12 13.0 0.3 3.3 8.4 0.3 3.1 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II BCNT PF07572.12 OAJ29998.1 - 6.1e-15 55.0 0.0 1.3e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Bucentaur or craniofacial development DUF1180 PF06679.12 OAJ29998.1 - 3.8 7.9 6.6 3.8 7.9 6.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) TANGO2 PF05742.12 OAJ29999.1 - 4.9e-49 167.7 0.0 6.1e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 RcsD_ABL PF16359.5 OAJ29999.1 - 0.26 11.5 0.0 0.41 10.8 0.0 1.2 1 0 0 1 1 1 0 RcsD-ABL domain KDZ PF18758.1 OAJ30000.1 - 4.5e-08 33.0 0.7 5.3e-08 32.7 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TF_Otx PF03529.13 OAJ30000.1 - 4.3 7.8 9.5 0.41 11.1 1.1 2.6 2 1 1 3 3 3 0 Otx1 transcription factor BRE1 PF08647.11 OAJ30001.1 - 0.0038 17.3 1.1 0.42 10.7 0.1 2.6 2 0 0 2 2 2 2 BRE1 E3 ubiquitin ligase DUF4746 PF15928.5 OAJ30001.1 - 3.8 6.9 6.8 6.7 6.1 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Abhydrolase_1 PF00561.20 OAJ30002.1 - 1.8e-36 126.1 0.1 2.3e-18 66.8 0.1 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold COX6A PF02046.15 OAJ30003.1 - 1.5e-26 93.0 0.9 1.1e-22 80.6 0.3 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VIa Orthopox_A5L PF06193.11 OAJ30004.1 - 0.029 13.8 1.1 0.046 13.2 1.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Sin_N PF04801.13 OAJ30004.1 - 2.3 7.3 5.6 3.4 6.8 5.6 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Git3 PF11710.8 OAJ30005.1 - 1.1e-09 38.4 8.8 3e-09 37.0 8.8 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 OAJ30005.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 OAJ30005.1 - 0.00053 20.0 0.5 0.0039 17.2 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Cwf_Cwc_15 PF04889.12 OAJ30005.1 - 3.7 7.2 5.3 7.3 6.3 0.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAR1 PF03101.15 OAJ30006.1 - 0.00047 20.8 0.0 0.00087 19.9 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain HECT PF00632.25 OAJ30007.1 - 1.8e-73 247.7 0.0 2.7e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Fungal_trans PF04082.18 OAJ30008.1 - 2.9e-11 42.9 0.2 4.5e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rhomboid PF01694.22 OAJ30009.1 - 6.6e-06 26.2 3.2 1.3e-05 25.3 3.2 1.5 1 1 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 OAJ30009.1 - 4.2e-05 24.1 2.9 4.7e-05 23.9 1.5 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 OAJ30009.1 - 0.0002 21.4 6.7 0.00029 20.8 2.8 2.0 2 0 0 2 2 2 1 Der1-like family DUF1631 PF07793.11 OAJ30009.1 - 0.98 7.8 2.5 1.3 7.4 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Oxidored_q2 PF00420.24 OAJ30009.1 - 1.4 8.6 5.5 0.18 11.4 1.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PH_12 PF16457.5 OAJ30010.1 - 6.2e-32 110.9 0.0 1.4e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 OAJ30010.1 - 7.1e-26 91.4 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 OAJ30010.1 - 1.2e-23 83.8 0.0 4.4e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_FH3 PF06367.16 OAJ30010.1 - 0.00097 18.8 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain V-ATPase_H_N PF03224.14 OAJ30010.1 - 0.012 14.9 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 V-ATPase subunit H PHF5 PF03660.14 OAJ30011.1 - 2.4e-46 156.2 8.3 2.6e-46 156.1 8.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 OAJ30011.1 - 0.0053 14.7 3.8 0.0054 14.7 3.8 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 OAJ30011.1 - 0.064 13.6 1.7 0.064 13.6 1.7 2.7 2 1 0 2 2 2 0 C1 domain DZR PF12773.7 OAJ30011.1 - 1.7 8.8 14.8 1.1 9.3 1.7 2.9 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 OAJ30012.1 - 1.2e-57 195.3 0.0 4.9e-31 108.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30012.1 - 1.4e-19 70.4 0.0 5.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAJ30012.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 OAJ30012.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 OAJ30012.1 - 0.19 11.6 3.9 0.32 10.9 0.2 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family BUD22 PF09073.10 OAJ30012.1 - 4.6 6.5 15.8 0.72 9.1 9.1 2.2 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 OAJ30012.1 - 6.6 4.9 8.2 3.3 5.9 5.6 1.8 2 0 0 2 2 2 0 CDC45-like protein BSP_II PF05432.11 OAJ30014.1 - 0.00046 20.0 12.5 0.00083 19.1 12.5 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) STE3 PF02076.15 OAJ30015.1 - 1.7e-87 293.3 15.0 2.3e-87 292.9 15.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Epiglycanin_C PF14654.6 OAJ30015.1 - 0.18 11.8 0.8 0.55 10.3 0.4 2.0 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region VWA_2 PF13519.6 OAJ30016.1 - 3.3e-22 79.2 0.0 6.1e-22 78.3 0.0 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 OAJ30016.1 - 2.1e-08 34.6 0.1 2.6e-08 34.3 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 OAJ30016.1 - 4.3e-06 26.7 0.0 5.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Ssl1-like Chorismate_bind PF00425.18 OAJ30016.1 - 0.083 12.4 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 chorismate binding enzyme Herpes_UL21 PF03252.13 OAJ30016.1 - 0.091 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Fer4_14 PF13394.6 OAJ30016.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain IATP PF04568.12 OAJ30017.1 - 1.2e-12 48.1 0.2 1.4e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP ATP_sub_h PF10775.9 OAJ30018.1 - 1.8e-23 82.3 1.3 2.8e-23 81.7 1.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h HTH_13 PF11972.8 OAJ30018.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Got1 PF04178.12 OAJ30019.1 - 7.1e-27 94.1 13.4 1e-26 93.5 13.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Acyl_transf_3 PF01757.22 OAJ30019.1 - 0.18 10.8 18.5 0.23 10.5 18.5 1.1 1 0 0 1 1 1 0 Acyltransferase family DUF2070 PF09843.9 OAJ30019.1 - 0.3 9.3 8.0 0.33 9.2 8.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short PF00106.25 OAJ30021.1 - 0.042 13.3 0.0 17 4.8 0.0 3.1 3 0 0 3 3 3 0 short chain dehydrogenase RTA1 PF04479.13 OAJ30022.1 - 3.1e-47 160.8 6.0 2.6e-36 125.2 0.3 2.4 3 0 0 3 3 3 2 RTA1 like protein TMEM237 PF15383.6 OAJ30022.1 - 0.29 10.2 1.0 0.58 9.2 1.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 237 peroxidase PF00141.23 OAJ30023.1 - 2.2e-49 168.2 0.0 3.1e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Transposase_21 PF02992.14 OAJ30024.1 - 3.8e-09 36.1 0.0 8.3e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Pyrophosphatase PF00719.19 OAJ30025.1 - 5.7e-60 201.7 0.2 7.2e-60 201.4 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase ChaC PF04752.12 OAJ30026.1 - 4.1e-51 173.6 0.0 8.1e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 ChaC-like protein DnaJ PF00226.31 OAJ30026.1 - 3.5e-25 87.9 0.9 9.1e-25 86.6 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 OAJ30026.1 - 1.2e-08 35.0 1.2 3.2e-08 33.6 1.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ30026.1 - 4.4e-06 26.9 0.5 8e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 OAJ30026.1 - 0.013 15.8 0.1 0.042 14.2 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) TetR_C_30 PF17939.1 OAJ30026.1 - 0.047 13.9 0.3 0.71 10.1 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain APOBEC_C PF05240.14 OAJ30026.1 - 0.096 12.7 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain zf-C2H2 PF00096.26 OAJ30026.1 - 0.68 10.5 1.7 0.87 10.2 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Lactamase_B_3 PF13483.6 OAJ30027.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF4218 PF13960.6 OAJ30029.1 - 0.00083 18.9 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CCDC53 PF10152.9 OAJ30030.1 - 0.01 16.3 0.4 0.026 15.0 0.0 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex NDT80_PhoG PF05224.12 OAJ30032.1 - 3e-09 37.4 0.0 2e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DDE_Tnp_1_4 PF13701.6 OAJ30032.1 - 0.046 12.0 0.1 0.066 11.5 0.1 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Ank_4 PF13637.6 OAJ30033.1 - 6.7e-14 52.1 0.0 9.4e-08 32.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ30033.1 - 8.2e-12 44.2 0.0 0.0005 20.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 OAJ30033.1 - 6.7e-11 42.6 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ30033.1 - 2.7e-10 40.3 0.3 9.2e-08 32.2 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 OAJ30033.1 - 1.8e-08 34.4 0.0 0.0028 18.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat HSF_DNA-bind PF00447.17 OAJ30034.1 - 8.2e-31 106.5 0.5 1.4e-30 105.7 0.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 OAJ30034.1 - 1.2e-24 86.7 0.1 2.4e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain RMI1_N PF08585.12 OAJ30034.1 - 0.053 13.3 0.4 0.095 12.4 0.4 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Bromodomain PF00439.25 OAJ30035.1 - 1.3e-14 54.0 0.1 3.1e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 Bromodomain CBM_6 PF03422.15 OAJ30035.1 - 0.033 14.5 1.5 0.53 10.6 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) LMF1 PF06762.14 OAJ30035.1 - 0.26 10.4 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor SMC_N PF02463.19 OAJ30036.1 - 5.3e-66 222.2 32.9 9.6e-65 218.1 32.9 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ30036.1 - 2.4e-24 85.9 0.0 7e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ30036.1 - 1.3e-12 48.7 4.0 1.3e-12 48.7 4.0 7.3 3 2 3 7 7 2 1 AAA domain AAA_21 PF13304.6 OAJ30036.1 - 7.6e-11 42.4 12.9 1.8e-05 24.8 0.0 4.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ30036.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 OAJ30036.1 - 0.00086 17.0 29.6 0.00086 17.0 29.6 4.5 4 1 0 4 4 3 1 Protein of unknown function (DUF3584) Img2 PF05046.14 OAJ30036.1 - 0.064 13.6 3.5 0.5 10.7 0.8 3.3 3 0 0 3 3 3 0 Mitochondrial large subunit ribosomal protein (Img2) Baculo_PEP_C PF04513.12 OAJ30036.1 - 0.12 12.4 15.4 0.21 11.7 0.5 4.9 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus SpoOE-like PF09388.10 OAJ30036.1 - 0.39 10.6 9.7 0.13 12.2 0.2 4.4 4 0 0 4 4 4 0 Spo0E like sporulation regulatory protein PKcGMP_CC PF16808.5 OAJ30036.1 - 0.68 9.8 16.8 0.2 11.5 0.3 6.2 5 1 1 6 6 6 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran PF00005.27 OAJ30036.1 - 1 9.9 0.0 1 9.9 0.0 6.3 4 2 0 5 5 4 0 ABC transporter SCAMP PF04144.13 OAJ30037.1 - 1.6e-48 165.3 3.3 1.9e-48 165.1 3.3 1.1 1 0 0 1 1 1 1 SCAMP family UCR_UQCRX_QCR9 PF05365.12 OAJ30037.1 - 0.022 14.7 1.3 0.13 12.2 0.3 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like SAE2 PF08573.10 OAJ30037.1 - 0.063 14.4 0.2 0.1 13.7 0.2 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Phage_holin_2_4 PF16082.5 OAJ30037.1 - 0.13 12.0 0.2 0.34 10.7 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3958 PF13125.6 OAJ30037.1 - 0.69 10.2 4.8 9 6.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) SAM_2 PF07647.17 OAJ30038.1 - 1.4e-08 34.7 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ30038.1 - 7.3e-05 23.1 0.0 0.00015 22.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 OAJ30038.1 - 0.068 13.4 0.6 0.14 12.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) IGR PF09597.10 OAJ30038.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Velvet PF11754.8 OAJ30039.1 - 6.2e-28 98.4 0.2 7.6e-28 98.1 0.2 1.0 1 0 0 1 1 1 1 Velvet factor FAM199X PF15814.5 OAJ30039.1 - 0.97 8.4 4.0 1.5 7.8 4.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X ISG65-75 PF11727.8 OAJ30040.1 - 0.006 15.8 6.7 0.0098 15.2 6.7 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein MarC PF01914.17 OAJ30040.1 - 0.41 10.0 0.6 0.89 8.9 0.6 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein NARP1 PF12569.8 OAJ30040.1 - 3.9 6.3 13.3 6.8 5.5 13.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 OAJ30040.1 - 6.2 5.5 4.5 11 4.6 4.5 1.4 1 0 0 1 1 1 0 Presenilin Glyco_hydro_16 PF00722.21 OAJ30041.1 - 4.4e-05 23.0 0.1 9.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Velvet PF11754.8 OAJ30042.1 - 2.5e-32 112.8 0.2 1.4e-19 71.1 0.1 3.4 2 2 1 3 3 3 2 Velvet factor FAM76 PF16046.5 OAJ30043.1 - 0.0051 16.2 0.3 0.0068 15.8 0.3 1.1 1 0 0 1 1 1 1 FAM76 protein CtIP_N PF10482.9 OAJ30043.1 - 0.051 13.6 1.6 0.084 12.9 1.6 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain ZapB PF06005.12 OAJ30043.1 - 0.061 13.8 4.0 0.12 12.9 4.0 1.4 1 0 0 1 1 1 0 Cell division protein ZapB Spond_N PF06468.13 OAJ30043.1 - 0.12 12.5 1.5 0.17 12.0 0.4 1.7 2 0 0 2 2 2 0 Spondin_N DUF3450 PF11932.8 OAJ30043.1 - 0.83 8.9 7.2 1.2 8.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BST2 PF16716.5 OAJ30043.1 - 1.1 9.9 5.6 1.7 9.3 5.6 1.3 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DivIC PF04977.15 OAJ30043.1 - 2.9 7.7 5.5 5.2 6.9 5.5 1.3 1 0 0 1 1 1 0 Septum formation initiator HECT_2 PF09814.9 OAJ30044.1 - 1.5e-32 112.9 0.0 1.8e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Peroxidase_2 PF01328.17 OAJ30046.1 - 1e-42 146.8 0.0 1.7e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 Solute_trans_a PF03619.16 OAJ30047.1 - 8.4e-85 284.5 25.2 1e-84 284.2 25.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.11 OAJ30047.1 - 0.005 17.0 2.1 0.005 17.0 2.1 2.1 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.13 OAJ30048.1 - 1.5e-33 116.4 0.0 2.1e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ30048.1 - 0.00014 21.4 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 OAJ30048.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 OAJ30048.1 - 0.0026 18.4 0.7 0.0051 17.4 0.7 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 OAJ30048.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) BAAT_C PF08840.11 OAJ30048.1 - 0.004 17.1 0.0 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 OAJ30048.1 - 0.0097 15.5 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 OAJ30048.1 - 0.024 13.9 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ANAPC5 PF12862.7 OAJ30049.1 - 2.2e-14 53.3 1.4 6.4e-14 51.8 1.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 OAJ30049.1 - 0.47 10.8 5.2 1.8 8.9 1.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ30049.1 - 2.8 8.3 6.1 21 5.6 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5074 PF16819.5 OAJ30050.1 - 0.096 12.7 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) LPD29 PF18847.1 OAJ30050.1 - 0.17 12.8 0.0 0.37 11.7 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 DUF4644 PF15486.6 OAJ30050.1 - 0.25 11.1 0.0 0.25 11.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4644) DUF5136 PF17199.4 OAJ30050.1 - 0.5 10.1 3.6 8.9 6.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF5136) HMGL-like PF00682.19 OAJ30051.1 - 8.2e-46 156.7 0.3 1.3e-44 152.7 0.3 2.5 1 1 0 1 1 1 1 HMGL-like ApoO PF09769.9 OAJ30052.1 - 3.8e-28 98.0 0.4 7.8e-28 97.0 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF3446 PF11928.8 OAJ30052.1 - 7.3 7.0 9.3 1.2 9.5 4.4 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain PAP_assoc PF03828.19 OAJ30053.1 - 2.4e-15 56.5 0.1 4.8e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 OAJ30053.1 - 1.1e-06 28.8 0.0 2.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ30053.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase ANAPC1 PF12859.7 OAJ30056.1 - 7.6e-12 45.9 4.6 3.6e-11 43.7 3.1 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 OAJ30056.1 - 0.00041 20.7 7.3 5.6 7.6 0.0 5.6 5 0 0 5 5 5 3 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.6 OAJ30057.1 - 8.1e-28 96.0 0.0 1.1e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ30057.1 - 7.7e-08 31.7 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 OAJ30058.1 - 1.4e-62 207.6 2.4 1.8e-23 82.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ku PF02735.16 OAJ30059.1 - 1.2e-23 83.9 0.1 1.1e-22 80.7 0.0 2.8 3 1 0 3 3 3 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 OAJ30059.1 - 5.5e-19 68.5 0.0 5.2e-18 65.3 0.0 2.6 3 0 0 3 3 3 1 Ku C terminal domain like Hexapep PF00132.24 OAJ30060.1 - 3.3e-07 29.8 14.0 0.066 13.0 1.2 4.0 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ30060.1 - 0.00093 18.9 12.3 0.031 14.0 3.8 3.4 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase MIF4G PF02854.19 OAJ30061.1 - 3.5e-13 49.7 0.0 1.7e-12 47.5 0.0 2.1 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 OAJ30061.1 - 6.2e-11 42.3 0.0 1.6e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 MA3 domain Nop14 PF04147.12 OAJ30061.1 - 0.0044 15.3 22.0 0.0068 14.7 22.0 1.2 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 OAJ30061.1 - 0.033 14.3 34.1 0.14 12.2 14.7 2.5 2 0 0 2 2 2 0 YL1 nuclear protein COX5B PF01215.19 OAJ30062.1 - 1e-46 157.8 0.0 1.3e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 OAJ30062.1 - 0.00021 21.3 0.4 0.00031 20.7 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain Chorismate_synt PF01264.21 OAJ30063.1 - 2.4e-138 460.3 0.1 2.7e-138 460.1 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase Vault PF01505.18 OAJ30064.1 - 0.22 11.7 1.0 0.56 10.4 0.4 2.0 2 0 0 2 2 2 0 Major Vault Protein repeat domain DUF1295 PF06966.12 OAJ30065.1 - 4.9e-42 144.1 0.0 8.9e-42 143.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 OAJ30065.1 - 0.045 14.2 0.0 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 OAJ30065.1 - 0.1 12.6 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Pilin_N PF07790.11 OAJ30065.1 - 0.16 12.9 0.0 0.41 11.6 0.0 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal MMR_HSR1_Xtn PF16897.5 OAJ30067.1 - 7.1e-39 132.1 0.1 1.4e-38 131.2 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAJ30067.1 - 4.3e-22 77.9 0.0 8.2e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAJ30067.1 - 1.1e-20 73.8 0.0 2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ30067.1 - 1.1e-09 38.0 0.1 3.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ30067.1 - 0.0012 18.9 0.1 0.3 11.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 OAJ30067.1 - 0.018 14.0 0.5 0.049 12.6 0.2 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 OAJ30067.1 - 0.064 12.8 0.6 8.8 5.8 0.6 3.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 OAJ30067.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RsgA_GTPase PF03193.16 OAJ30067.1 - 0.26 11.2 1.6 5.7 6.8 0.1 2.8 2 1 1 3 3 3 0 RsgA GTPase PLDc_2 PF13091.6 OAJ30068.1 - 5.3e-17 62.0 0.0 4.5e-11 42.8 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain ERG2_Sigma1R PF04622.12 OAJ30069.1 - 5.6e-88 293.7 0.0 7.7e-88 293.3 0.0 1.2 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein C1_1 PF00130.22 OAJ30069.1 - 0.07 13.0 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RNA_POL_M_15KD PF02150.16 OAJ30069.1 - 0.076 12.9 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit RRM_1 PF00076.22 OAJ30070.1 - 2.5e-31 107.3 0.0 5.6e-12 45.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ30070.1 - 0.0011 18.5 0.0 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 OAJ30070.1 - 0.17 11.4 8.5 0.36 10.4 8.5 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ30070.1 - 4.2 7.2 10.1 0.25 11.3 4.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macro PF01661.21 OAJ30071.1 - 6.2e-42 142.4 0.1 9e-42 141.8 0.1 1.2 1 0 0 1 1 1 1 Macro domain BcrAD_BadFG PF01869.20 OAJ30072.1 - 1.2e-05 24.9 0.1 0.00017 21.2 0.1 2.1 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family CDC45 PF02724.14 OAJ30072.1 - 0.00082 17.8 0.6 0.00082 17.8 0.6 2.2 2 1 0 2 2 2 1 CDC45-like protein NOA36 PF06524.12 OAJ30072.1 - 2.2 7.5 10.4 5.6 6.2 10.4 1.6 1 0 0 1 1 1 0 NOA36 protein Aminotran_3 PF00202.21 OAJ30073.1 - 7.7e-121 403.5 0.0 9.6e-121 403.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 OAJ30073.1 - 0.04 13.2 0.0 0.24 10.6 0.0 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase Alpha_GJ PF03229.13 OAJ30073.1 - 4.7 7.8 8.6 1.3 9.6 5.4 1.7 2 0 0 2 2 2 0 Alphavirus glycoprotein J VPS9 PF02204.18 OAJ30075.1 - 3.7e-31 107.4 0.1 7e-31 106.5 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 OAJ30075.1 - 9.6e-12 45.0 0.0 2.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) SNARE PF05739.19 OAJ30075.1 - 0.01 15.8 1.7 0.023 14.7 0.0 2.3 3 0 0 3 3 3 0 SNARE domain Pre-PUA PF17832.1 OAJ30076.1 - 1.3e-24 86.7 0.0 1.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 OAJ30076.1 - 3.7e-15 55.6 0.0 6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 PUA domain MgtE PF01769.16 OAJ30077.1 - 4.6e-33 114.2 35.3 1.8e-20 73.6 4.0 4.6 4 1 0 4 4 4 2 Divalent cation transporter Ribosomal_L23eN PF03939.13 OAJ30078.1 - 1.5e-21 76.4 10.8 2.8e-21 75.5 10.8 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 OAJ30078.1 - 1.1e-10 41.7 2.5 1.2e-10 41.6 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 DUF5451 PF17532.2 OAJ30078.1 - 0.0088 16.3 0.8 0.012 15.8 0.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5451) Cyt-b5 PF00173.28 OAJ30079.1 - 5.9e-08 32.7 0.0 7.3e-08 32.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Arrestin_C PF02752.22 OAJ30080.1 - 3.8e-10 40.4 0.0 8.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ribosomal_L22 PF00237.19 OAJ30081.1 - 1.6e-34 118.2 0.1 2.2e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF2235 PF09994.9 OAJ30083.1 - 5.6e-41 140.8 0.0 1e-40 139.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-RING_2 PF13639.6 OAJ30084.1 - 0.12 12.7 3.3 0.2 12.0 3.3 1.3 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 OAJ30084.1 - 0.96 9.8 4.9 1.8 8.9 4.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain DHBP_synthase PF00926.19 OAJ30085.1 - 7.3e-75 250.7 0.0 8.7e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GbpA_2 PF18416.1 OAJ30086.1 - 0.15 12.4 0.3 0.5 10.7 0.1 2.0 2 0 0 2 2 2 0 N-acetylglucosamine binding protein domain 2 Pex14_N PF04695.13 OAJ30086.1 - 0.25 12.0 5.3 0.37 11.4 5.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-Tim10_DDP PF02953.15 OAJ30087.1 - 0.071 12.8 3.7 0.45 10.2 0.3 2.2 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Thionin PF00321.17 OAJ30087.1 - 0.072 13.6 5.6 0.83 10.2 0.4 2.2 2 0 0 2 2 2 0 Plant thionin Toxin_25 PF08095.11 OAJ30087.1 - 0.93 9.5 7.8 2.1 8.4 0.4 2.7 2 1 0 2 2 2 0 Hefutoxin family Peptidase_S8 PF00082.22 OAJ30088.1 - 4.7e-40 137.7 2.8 8.3e-40 136.9 2.8 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ30088.1 - 4.6e-13 49.9 0.1 8.6e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAJ30088.1 - 0.0003 20.7 0.0 0.00087 19.3 0.0 1.8 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.16 OAJ30088.1 - 0.066 13.9 0.0 0.27 11.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase inhibitor I9 Cyt-b5 PF00173.28 OAJ30089.1 - 1.5e-12 47.4 0.0 2.1e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AfsA PF03756.13 OAJ30090.1 - 0.053 13.5 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain RVT_2 PF07727.14 OAJ30091.1 - 4.1e-61 206.7 0.0 5.6e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ30091.1 - 5.2e-23 81.5 0.3 4e-22 78.6 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ30091.1 - 2.2e-05 24.2 0.0 8.2e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ30091.1 - 0.0098 15.7 0.2 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 OAJ30092.1 - 2.6e-07 30.8 0.2 9.4e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Retrotran_gag_2 PF14223.6 OAJ30092.1 - 9.9e-07 28.5 0.1 1.9e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 OAJ30092.1 - 0.1 12.3 1.9 0.2 11.4 1.9 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Carn_acyltransf PF00755.20 OAJ30095.1 - 1.9e-197 657.6 0.0 2.5e-197 657.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rho_GDI PF02115.17 OAJ30096.1 - 8e-54 182.4 0.0 9.7e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Holin_BhlA PF10960.8 OAJ30097.1 - 0.23 11.4 0.1 0.55 10.2 0.1 1.6 1 0 0 1 1 1 0 BhlA holin family BUD22 PF09073.10 OAJ30097.1 - 1.6 8.0 4.3 2.3 7.5 4.3 1.1 1 0 0 1 1 1 0 BUD22 PRKCSH PF07915.13 OAJ30099.1 - 6.7e-11 43.0 0.0 7.6e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein SLAC1 PF03595.17 OAJ30100.1 - 7.6e-63 212.7 45.6 1.2e-62 212.0 45.6 1.3 1 0 0 1 1 1 1 Voltage-dependent anion channel Snapin_Pallidin PF14712.6 OAJ30101.1 - 0.026 15.0 0.3 0.034 14.6 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Dimerisation PF08100.11 OAJ30101.1 - 0.061 13.4 0.2 24 5.1 0.0 2.9 1 1 2 3 3 3 0 Dimerisation domain adh_short PF00106.25 OAJ30105.1 - 4e-18 65.6 0.3 5.3e-07 29.3 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ30105.1 - 4.6e-09 36.2 0.5 2.8e-05 23.8 0.0 2.8 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ30105.1 - 3.4e-06 27.1 0.1 1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 KR domain AhpC-TSA_2 PF13911.6 OAJ30106.1 - 7.9e-15 55.0 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ30106.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Redoxin NAD_binding_7 PF13241.6 OAJ30106.1 - 0.1 13.0 0.0 0.15 12.5 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding RCC1 PF00415.18 OAJ30107.1 - 6.2e-37 126.0 5.3 7.5e-08 32.9 0.0 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ30107.1 - 7.9e-22 76.5 13.2 3.1e-05 23.6 0.0 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 OAJ30107.1 - 2.2e-10 40.3 11.0 2.2e-10 40.3 11.0 1.7 2 0 0 2 2 2 1 PHD-finger ADK_lid PF05191.14 OAJ30107.1 - 0.0075 16.2 2.1 0.03 14.3 1.3 2.3 2 0 0 2 2 2 1 Adenylate kinase, active site lid Prok-RING_1 PF14446.6 OAJ30107.1 - 1.4 8.9 9.7 0.28 11.1 5.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 OAJ30107.1 - 1.6 8.6 11.1 0.57 10.1 5.5 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_transf_41 PF13844.6 OAJ30108.1 - 1.3e-101 340.4 1.3 3.2e-48 164.3 0.0 4.2 3 1 1 4 4 4 4 Glycosyl transferase family 41 TPR_1 PF00515.28 OAJ30108.1 - 5e-19 67.3 0.0 6.7e-05 22.5 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ30108.1 - 1.4e-16 59.8 1.4 8e-06 25.5 0.1 5.0 3 1 2 5 5 5 3 TPR repeat TPR_17 PF13431.6 OAJ30108.1 - 9.7e-16 56.9 0.8 6e-05 23.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ30108.1 - 5.2e-14 51.2 0.0 0.0031 17.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ30108.1 - 7.1e-11 41.4 0.0 0.00049 20.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ30108.1 - 2.2e-10 40.1 9.2 0.0014 18.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ30108.1 - 3.3e-08 33.7 4.8 0.2 12.6 0.0 5.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ30108.1 - 1e-07 32.3 0.0 0.092 13.3 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ30108.1 - 2.6e-07 30.8 0.0 0.77 10.1 0.0 4.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ30108.1 - 8.7e-05 22.3 0.1 2 8.6 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ30108.1 - 0.0066 16.6 0.0 0.061 13.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat MAM33 PF02330.16 OAJ30109.1 - 1.7e-60 204.6 0.0 2e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein NESP55 PF06390.12 OAJ30109.1 - 3.5 7.1 13.9 0.22 11.1 8.7 1.5 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pyridoxal_deC PF00282.19 OAJ30111.1 - 5.6e-21 74.7 0.0 8e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ30111.1 - 2.4e-10 39.9 0.0 4.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 OAJ30111.1 - 0.0084 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CHCH PF06747.13 OAJ30112.1 - 3.5e-06 27.0 3.9 6.4e-06 26.2 3.9 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 OAJ30112.1 - 0.018 15.5 4.1 0.034 14.6 4.1 1.5 1 0 0 1 1 1 0 GCK domain UPF0220 PF05255.11 OAJ30113.1 - 8e-50 168.6 0.0 9.9e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) GSAP-16 PF14959.6 OAJ30115.1 - 0.24 11.3 0.1 0.47 10.3 0.1 1.4 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term adh_short PF00106.25 OAJ30116.1 - 9.5e-25 87.2 0.0 6.1e-16 58.5 0.1 2.7 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ30116.1 - 4.6e-14 52.5 0.0 1.4e-12 47.7 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ30116.1 - 5.3e-08 32.6 0.0 7.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ30116.1 - 0.00029 20.8 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 OAJ30116.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) MBG PF17883.1 OAJ30116.1 - 0.04 14.5 0.1 0.074 13.7 0.0 1.4 1 1 0 1 1 1 0 MBG domain MoCF_biosynth PF00994.24 OAJ30117.1 - 2.3e-33 114.9 0.0 4.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAP1 PF08601.10 OAJ30117.1 - 0.044 13.5 1.4 0.066 12.9 1.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Erp_C PF06780.11 OAJ30117.1 - 0.16 12.0 0.2 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus ELO PF01151.18 OAJ30118.1 - 1.8e-54 184.9 6.8 2.3e-54 184.6 6.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family LPD24 PF18839.1 OAJ30118.1 - 0.39 11.0 2.1 0.5 10.7 0.7 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 MaoC_dehydratas PF01575.19 OAJ30119.1 - 1.2e-23 83.0 0.0 2.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 OAJ30119.1 - 4.6e-06 26.8 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Antimicrobial_5 PF08026.11 OAJ30119.1 - 2 8.6 7.8 9.9 6.3 2.4 3.2 3 0 0 3 3 3 0 Bee antimicrobial peptide Vfa1 PF08432.10 OAJ30120.1 - 3.6e-33 115.4 0.1 8.2e-33 114.2 0.1 1.5 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 PV-1 PF06637.11 OAJ30120.1 - 0.047 12.5 2.9 0.069 12.0 2.9 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) SKA1 PF07160.12 OAJ30120.1 - 0.14 12.0 1.6 0.19 11.5 1.6 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF5427 PF10310.9 OAJ30120.1 - 0.18 10.7 4.5 0.23 10.4 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Coprogen_oxidas PF01218.18 OAJ30121.1 - 4.8e-124 412.9 0.0 1.2e-123 411.6 0.0 1.7 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase RskA PF10099.9 OAJ30121.1 - 0.043 14.1 6.6 0.097 13.0 6.6 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sacchrp_dh_NADP PF03435.18 OAJ30122.1 - 6.4e-16 58.8 0.1 1e-15 58.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 OAJ30122.1 - 1e-06 28.4 0.1 1.6e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ30122.1 - 1.8e-06 27.9 0.2 4.3e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 OAJ30122.1 - 0.00018 21.1 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 OAJ30122.1 - 0.0004 19.9 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ30122.1 - 0.0018 17.3 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 OAJ30122.1 - 0.004 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 OAJ30122.1 - 0.014 15.8 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 OAJ30122.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 OAJ30122.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.12 OAJ30122.1 - 0.072 12.2 0.3 0.41 9.8 0.1 2.3 2 1 0 2 2 2 0 Male sterility protein NTF2 PF02136.20 OAJ30123.1 - 0.11 13.1 0.0 5.3 7.6 0.0 3.0 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain TRAPPC-Trs85 PF12739.7 OAJ30124.1 - 3.4e-101 339.2 0.0 4.9e-101 338.6 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit WD40 PF00400.32 OAJ30125.1 - 2.3e-10 40.9 14.0 0.012 16.4 0.0 6.7 5 2 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ30125.1 - 0.00045 20.5 0.0 8.5 6.7 0.0 4.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HHH PF00633.23 OAJ30126.1 - 0.014 15.2 0.1 0.039 13.8 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Raftlin PF15250.6 OAJ30126.1 - 3.5 6.3 12.8 5.5 5.6 12.8 1.2 1 0 0 1 1 1 0 Raftlin 2-Hacid_dh_C PF02826.19 OAJ30127.1 - 4.2e-52 176.1 0.0 7.3e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 OAJ30127.1 - 2.2e-35 121.3 0.0 2.8e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 OAJ30127.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase BRCA-2_OB1 PF09103.10 OAJ30128.1 - 2.4e-32 111.5 0.0 3.9e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 OAJ30128.1 - 1.4e-07 31.4 0.2 2.6e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 BRCA2, helical BRCA2 PF00634.18 OAJ30128.1 - 0.0092 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 BRCA2 repeat Aldedh PF00171.22 OAJ30129.1 - 7.3e-105 351.1 0.1 8.7e-105 350.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ERCC4 PF02732.15 OAJ30131.1 - 2.3e-20 73.4 0.0 4.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain SAM_PNT PF02198.16 OAJ30131.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Pyridox_oxase_2 PF12766.7 OAJ30132.1 - 2.7e-21 76.0 0.0 4.1e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HhH-GPD PF00730.25 OAJ30133.1 - 2.4e-17 63.3 0.0 3.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 OAJ30133.1 - 6.3e-08 32.1 0.0 1.8e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif cwf18 PF08315.12 OAJ30133.1 - 0.021 15.5 5.7 0.021 15.5 5.7 1.6 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor HHH_5 PF14520.6 OAJ30133.1 - 0.039 14.6 0.0 0.2 12.3 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Tfb2 PF03849.14 OAJ30134.1 - 3.5e-135 450.6 0.0 4.3e-135 450.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 OAJ30134.1 - 1.5e-23 83.0 0.6 4.4e-23 81.5 0.6 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 OAJ30134.1 - 0.0002 21.5 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NIF PF03031.18 OAJ30135.1 - 8.7e-22 77.6 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 OAJ30135.1 - 0.0082 15.9 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family TAFII55_N PF04658.13 OAJ30136.1 - 7e-51 172.1 0.2 7e-51 172.1 0.2 2.2 3 0 0 3 3 3 1 TAFII55 protein conserved region SUIM_assoc PF16619.5 OAJ30136.1 - 4.9e-05 23.3 2.1 0.00037 20.5 2.1 2.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CBM_26 PF16824.5 OAJ30137.1 - 0.13 12.4 0.0 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 C-terminal carbohydrate-binding module APG6 PF04111.12 OAJ30140.1 - 5.7e-65 218.6 0.0 1e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 OAJ30140.1 - 1.5e-24 87.0 19.5 1.5e-24 87.0 19.5 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region SOGA PF11365.8 OAJ30140.1 - 0.28 12.4 12.3 1.1 10.5 8.3 3.3 2 1 1 3 3 3 0 Protein SOGA YabA PF06156.13 OAJ30140.1 - 0.45 11.2 3.7 0.71 10.5 2.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 OAJ30140.1 - 0.99 7.9 3.0 1.5 7.4 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 OAJ30140.1 - 2.8 8.2 6.5 1.3 9.3 3.7 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Glyco_transf_21 PF13506.6 OAJ30141.1 - 3.2e-24 85.3 0.1 7e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 OAJ30141.1 - 1.4e-13 51.2 0.0 5.5e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 OAJ30141.1 - 0.021 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 PrgI PF12666.7 OAJ30141.1 - 0.42 11.3 1.9 0.59 10.9 0.4 2.0 2 0 0 2 2 2 0 PrgI family protein SPC22 PF04573.12 OAJ30142.1 - 5.5e-53 179.0 0.3 6.2e-53 178.8 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit IMS PF00817.20 OAJ30143.1 - 5.9e-45 152.9 0.2 1e-44 152.1 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 OAJ30143.1 - 2.3e-12 47.6 0.6 6.2e-12 46.3 0.6 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 OAJ30143.1 - 0.0014 18.9 0.0 0.0029 17.8 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif PRA1 PF03208.19 OAJ30144.1 - 1.1e-33 115.9 0.1 1.3e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 PRA1 family protein YrhK PF14145.6 OAJ30144.1 - 2.4 8.1 8.0 1.9 8.4 1.9 2.3 2 0 0 2 2 2 0 YrhK-like protein Sugar_tr PF00083.24 OAJ30145.1 - 1.8e-40 139.2 12.8 3.2e-40 138.4 12.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ30145.1 - 6e-25 87.9 26.6 2.1e-12 46.7 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C54 PF03416.19 OAJ30146.1 - 2e-99 332.5 0.0 3.3e-99 331.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 SKI PF01202.22 OAJ30147.1 - 1.4e-05 25.3 0.1 0.0008 19.6 0.0 2.6 2 1 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 OAJ30147.1 - 1.8e-05 25.3 1.7 0.0055 17.3 0.2 2.7 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAJ30147.1 - 0.00018 21.7 0.3 0.011 15.9 0.3 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 OAJ30147.1 - 0.0017 18.0 0.9 0.0032 17.1 0.3 1.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ30147.1 - 0.004 17.4 0.8 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 OAJ30147.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase dNK PF01712.19 OAJ30147.1 - 0.038 13.9 0.2 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase APS_kinase PF01583.20 OAJ30147.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 OAJ30147.1 - 0.13 12.4 1.7 0.38 10.9 0.0 2.4 2 1 1 3 3 3 0 Cytidylate kinase-like family AAA_29 PF13555.6 OAJ30147.1 - 0.15 11.8 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 OAJ30147.1 - 0.2 12.1 1.5 27 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF305 PF03713.13 OAJ30147.1 - 0.55 10.4 4.1 0.13 12.4 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF305) AAA_16 PF13191.6 OAJ30147.1 - 1.6 9.1 4.1 2.9 8.3 4.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Cytochrom_D1 PF02239.16 OAJ30148.1 - 0.21 10.0 0.0 0.39 9.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Enkurin PF13864.6 OAJ30148.1 - 0.49 10.9 3.9 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Calmodulin-binding rve PF00665.26 OAJ30149.1 - 1.2e-17 64.2 0.0 3.6e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ30149.1 - 5e-17 61.8 0.0 1.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ30149.1 - 4.1e-15 55.9 0.0 9.2e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 OAJ30149.1 - 6.6e-15 55.0 0.2 1.5e-14 53.9 0.2 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain gag-asp_proteas PF13975.6 OAJ30149.1 - 4.4e-06 27.2 0.0 1.4e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ30149.1 - 4.9e-06 27.1 0.0 1.2e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.27 OAJ30149.1 - 0.00019 21.0 0.0 0.00069 19.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SR-25 PF10500.9 OAJ30149.1 - 0.0069 16.0 29.6 0.02 14.5 29.6 1.7 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-H2C2 PF09337.10 OAJ30149.1 - 0.066 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 H2C2 zinc finger rve_3 PF13683.6 OAJ30149.1 - 0.14 12.0 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain SAPS PF04499.15 OAJ30149.1 - 1.3 7.7 5.3 2 7.1 5.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4698 PF15769.5 OAJ30149.1 - 1.7 7.6 8.5 0.43 9.6 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4698) zf-CCHC PF00098.23 OAJ30149.1 - 2 8.6 4.1 4.3 7.6 4.1 1.6 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.14 OAJ30149.1 - 3.6 5.8 17.0 6.2 5.0 17.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 OAJ30149.1 - 4.6 5.7 31.2 8.1 4.9 31.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 OAJ30149.1 - 6 5.6 18.0 9.3 5.0 18.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-6 PF01912.18 OAJ30150.1 - 3.9e-79 264.6 0.3 4.5e-79 264.4 0.3 1.0 1 0 0 1 1 1 1 eIF-6 family Cutinase PF01083.22 OAJ30151.1 - 5.7e-24 85.0 0.2 6.9e-24 84.8 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 OAJ30151.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Nop14 PF04147.12 OAJ30152.1 - 0.62 8.2 10.5 0.12 10.5 0.6 2.2 2 0 0 2 2 2 0 Nop14-like family S-antigen PF05756.11 OAJ30152.1 - 3 8.3 4.7 7.5 7.0 4.7 1.6 1 0 0 1 1 1 0 S-antigen protein DPBB_1 PF03330.18 OAJ30153.1 - 0.00059 20.1 0.7 0.002 18.4 0.7 2.0 1 1 0 1 1 1 1 Lytic transglycolase SAPS PF04499.15 OAJ30154.1 - 9.7e-145 483.1 0.0 3.6e-144 481.2 0.0 1.9 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein TSP9 PF11493.8 OAJ30154.1 - 1 10.0 0.0 1 10.0 0.0 4.1 6 0 0 6 6 6 0 Thylakoid soluble phosphoprotein TSP9 HORMA PF02301.18 OAJ30155.1 - 6.8e-51 172.9 0.7 2.2e-50 171.2 0.0 2.2 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 OAJ30155.1 - 1.4e-08 34.5 4.8 2.5e-08 33.7 4.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ30155.1 - 0.0012 18.4 1.8 0.002 17.7 1.8 1.4 1 0 0 1 1 1 1 PHD-finger RSS_P20 PF11757.8 OAJ30155.1 - 0.76 10.3 2.4 2.2 8.8 2.4 1.8 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Lactamase_B PF00753.27 OAJ30156.1 - 4.6e-07 30.0 1.2 0.0063 16.5 0.1 2.6 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 OAJ30156.1 - 4.7e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 OAJ30156.1 - 0.018 14.5 0.3 0.034 13.6 0.3 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FA_hydroxylase PF04116.13 OAJ30157.1 - 6.8e-22 78.2 16.5 6.8e-22 78.2 16.5 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 OAJ30157.1 - 0.097 10.6 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein WD40 PF00400.32 OAJ30158.1 - 1.9e-22 79.1 3.2 1.8e-07 31.7 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 OAJ30158.1 - 0.015 13.8 0.0 0.032 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF4666 PF15697.5 OAJ30158.1 - 1 10.1 7.3 0.16 12.6 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) TAF4 PF05236.14 OAJ30159.1 - 1.9e-27 96.8 34.7 5.2e-22 78.9 9.8 4.1 2 1 1 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 OAJ30159.1 - 0.003 17.3 0.3 0.003 17.3 0.3 2.0 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Y_phosphatase PF00102.27 OAJ30160.1 - 4e-28 98.6 0.0 4.6e-13 49.3 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 OAJ30160.1 - 2.5e-06 27.3 0.0 5.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UvdE PF03851.14 OAJ30162.1 - 5.7e-91 304.6 0.0 8.1e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE G-alpha PF00503.20 OAJ30163.1 - 1e-113 380.1 0.0 1.2e-113 380.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ30163.1 - 1.3e-14 54.1 0.1 7.3e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ30163.1 - 2.2e-05 24.0 0.1 0.085 12.2 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 OAJ30163.1 - 0.0033 17.7 0.1 0.54 10.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ30163.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DIM1 PF02966.16 OAJ30164.1 - 8.9e-66 219.7 0.1 1e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 OAJ30164.1 - 0.00069 19.6 0.0 0.00087 19.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ30164.1 - 0.027 14.8 0.1 0.042 14.2 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like DUF3192 PF11399.8 OAJ30164.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) RBR PF17208.3 OAJ30165.1 - 0.0017 19.0 1.4 0.0035 18.0 0.1 2.2 2 0 0 2 2 2 1 RNA binding Region Peptidase_C2 PF00648.21 OAJ30166.1 - 3.5e-23 82.1 0.0 6.9e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 OAJ30166.1 - 1.6e-17 64.1 0.0 1.3e-08 35.2 0.0 3.1 3 0 0 3 3 3 2 Calpain large subunit, domain III Myb_Cef PF11831.8 OAJ30167.1 - 2.8e-56 190.7 0.3 2.8e-56 190.7 0.3 4.3 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 OAJ30167.1 - 3e-23 81.7 4.5 4.2e-11 42.8 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ30167.1 - 8.7e-20 70.7 6.9 4.6e-13 49.2 3.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2271 PF10029.9 OAJ30167.1 - 0.0086 15.7 0.3 0.02 14.5 0.3 1.6 1 0 0 1 1 1 1 Predicted periplasmic protein (DUF2271) VAPB_antitox PF02697.14 OAJ30167.1 - 0.013 16.3 1.8 0.095 13.5 1.8 2.6 1 0 0 1 1 1 0 Putative antitoxin Rap1_C PF11626.8 OAJ30167.1 - 0.2 11.8 1.2 2.2 8.4 0.1 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sec1 PF00995.23 OAJ30168.1 - 2.7e-26 93.0 0.4 3.1e-26 92.8 0.4 1.0 1 0 0 1 1 1 1 Sec1 family F-box PF00646.33 OAJ30169.1 - 1.8e-07 30.8 0.3 3.7e-07 29.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ30169.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 OAJ30169.1 - 0.00044 20.1 1.9 0.00064 19.6 0.2 2.2 3 0 0 3 3 3 1 F-box-like HA2 PF04408.23 OAJ30170.1 - 8.1e-24 84.0 0.2 1.6e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ30170.1 - 2.5e-18 66.2 0.0 6.3e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ30170.1 - 2.7e-09 37.3 0.0 5.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ30170.1 - 8.3e-07 29.4 0.0 2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 OAJ30170.1 - 3.4e-06 26.9 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 OAJ30170.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 OAJ30170.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 OAJ30170.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 OAJ30170.1 - 0.021 14.5 0.1 0.078 12.6 0.1 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 OAJ30170.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 OAJ30170.1 - 0.023 14.1 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 OAJ30170.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Serglycin PF04360.12 OAJ30170.1 - 0.23 11.4 3.1 0.47 10.4 3.1 1.4 1 0 0 1 1 1 0 Serglycin PRELI PF04707.14 OAJ30171.1 - 3.5e-32 111.4 0.0 3.6e-24 85.4 0.0 2.0 2 0 0 2 2 2 2 PRELI-like family Cid2 PF09774.9 OAJ30172.1 - 5.3e-23 82.2 1.0 5.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Caffeine-induced death protein 2 DUF4590 PF15257.6 OAJ30173.1 - 0.016 15.1 1.7 0.02 14.8 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) NDC10_II PF16787.5 OAJ30175.1 - 8.1e-64 215.7 0.0 1.2e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ30175.1 - 5.3e-17 61.9 1.8 1e-16 61.0 1.8 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes CCDC24 PF15669.5 OAJ30175.1 - 0.00038 20.4 0.8 0.00081 19.3 0.8 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Hist_deacetyl PF00850.19 OAJ30176.1 - 1.2e-81 274.6 0.1 2.2e-81 273.7 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Herpes_UL32 PF06070.11 OAJ30176.1 - 0.26 9.0 2.4 0.48 8.1 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DDHD PF02862.17 OAJ30178.1 - 1.3 9.1 5.0 3.9 7.6 0.0 2.2 1 1 1 2 2 2 0 DDHD domain PikAIV_N PF18605.1 OAJ30179.1 - 0.065 12.8 3.3 0.16 11.6 3.3 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain SIKE PF05769.11 OAJ30179.1 - 0.24 11.3 0.1 0.36 10.7 0.1 1.2 1 0 0 1 1 1 0 SIKE family tRNA-synt_2 PF00152.20 OAJ30180.1 - 2.6e-71 240.3 0.0 3.6e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 OAJ30180.1 - 2.7e-15 56.2 0.1 4.5e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 OAJ30180.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ30180.1 - 0.011 15.3 0.2 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Acetyltransf_6 PF13480.7 OAJ30180.1 - 0.042 14.0 2.1 0.081 13.1 0.8 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 OAJ30182.1 - 4e-36 124.9 1.5 4.6e-30 105.1 1.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 OAJ30182.1 - 2.8e-09 36.4 0.2 7.1e-09 35.1 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Lactamase_B_2 PF12706.7 OAJ30182.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain AXE1 PF05448.12 OAJ30182.1 - 0.19 10.4 0.1 3.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) zf-C2H2_2 PF12756.7 OAJ30183.1 - 1.7e-35 121.4 2.3 9.6e-28 96.5 0.0 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAJ30183.1 - 2.4e-09 37.3 12.0 1.3e-06 28.5 0.7 3.4 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ30183.1 - 6.3e-07 29.6 5.2 8.8e-07 29.1 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 OAJ30183.1 - 0.00043 20.9 10.6 0.35 11.8 0.1 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ30183.1 - 0.007 16.3 2.4 0.25 11.4 0.4 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger ARS2 PF04959.13 OAJ30183.1 - 0.093 13.1 0.0 15 5.9 0.0 2.3 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2 PF00096.26 OAJ30183.1 - 0.28 11.7 18.9 0.43 11.1 0.3 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type DUF4231 PF14015.6 OAJ30183.1 - 0.65 10.5 5.3 7.9 7.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4674 PF15719.5 OAJ30183.1 - 0.79 9.7 9.5 2.5 8.1 9.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) DUF4551 PF15087.6 OAJ30183.1 - 0.83 8.4 8.4 1.2 7.9 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Nop PF01798.18 OAJ30185.1 - 1.4e-70 237.4 0.0 2.3e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 OAJ30185.1 - 1.6e-37 129.1 7.5 1.6e-37 129.1 7.5 2.1 2 0 0 2 2 2 1 Prp31 C terminal domain NOA36 PF06524.12 OAJ30185.1 - 1.5 8.1 16.8 2.8 7.2 16.8 1.4 1 0 0 1 1 1 0 NOA36 protein F-box-like PF12937.7 OAJ30186.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like Toxin_20 PF08089.11 OAJ30187.1 - 5.7 7.1 9.9 1 9.6 2.2 3.0 3 0 0 3 3 3 0 Huwentoxin-II family DUF3437 PF11919.8 OAJ30188.1 - 1.1e-27 95.8 0.1 1.5e-25 88.9 0.1 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 OAJ30188.1 - 0.00043 20.6 0.2 0.038 14.4 0.0 3.9 3 2 2 5 5 5 1 HEAT repeats BLM10_mid PF16507.5 OAJ30188.1 - 0.0034 16.1 0.0 0.082 11.6 0.0 2.9 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region HEAT PF02985.22 OAJ30188.1 - 0.0042 17.2 0.0 0.4 11.1 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat DUF4404 PF14357.6 OAJ30188.1 - 1 10.1 3.5 3.5 8.3 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Npa1 PF11707.8 OAJ30189.1 - 3.3e-75 253.6 0.4 1.2e-45 156.4 0.0 3.8 4 1 0 4 4 4 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 OAJ30189.1 - 9.8e-47 159.1 0.6 2.9e-46 157.6 0.6 1.9 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Na_Ca_ex PF01699.24 OAJ30190.1 - 1.5e-45 154.9 40.4 1.7e-25 89.7 15.2 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4027 PF13219.6 OAJ30190.1 - 0.077 12.9 0.9 0.26 11.2 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) SelP_N PF04592.14 OAJ30190.1 - 4.5 6.6 20.7 7.2 5.9 2.9 2.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Lactonase PF10282.9 OAJ30191.1 - 1.4e-67 228.5 0.0 1.7e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cadherin_4 PF17803.1 OAJ30191.1 - 5.6 7.7 13.1 3.3 8.4 5.2 3.7 2 2 0 2 2 2 0 Bacterial cadherin-like domain NIF PF03031.18 OAJ30194.1 - 2.4e-07 30.6 0.0 0.0048 16.7 0.0 3.2 4 0 0 4 4 4 2 NLI interacting factor-like phosphatase GNAT_acetyltr_2 PF13718.6 OAJ30195.1 - 1.1e-74 250.6 0.0 2.2e-74 249.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 OAJ30195.1 - 4.6e-53 180.3 0.3 2e-32 112.8 0.0 2.4 1 1 1 2 2 2 2 Possible tRNA binding domain Helicase_RecD PF05127.14 OAJ30195.1 - 1.3e-50 171.7 0.0 2.2e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 OAJ30195.1 - 1.4e-27 95.4 0.0 3.3e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) Endonuclease_NS PF01223.23 OAJ30196.1 - 5.6e-54 183.3 0.0 4.9e-48 163.9 0.0 2.1 1 1 1 2 2 2 2 DNA/RNA non-specific endonuclease rve PF00665.26 OAJ30197.1 - 1.3e-05 25.3 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain BLM10_mid PF16507.5 OAJ30198.1 - 2.7e-116 389.3 0.0 3.9e-116 388.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 OAJ30198.1 - 1e-17 63.8 0.0 8.9e-17 60.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 OAJ30198.1 - 0.00093 19.5 0.2 0.054 13.9 0.0 3.7 2 1 0 2 2 2 1 HEAT repeats TetR_C_30 PF17939.1 OAJ30198.1 - 0.098 12.9 2.3 2.1 8.6 0.0 3.8 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain HLH PF00010.26 OAJ30198.1 - 0.13 12.3 0.0 0.48 10.4 0.0 2.0 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zf_C2H2_6 PF18450.1 OAJ30198.1 - 0.48 10.2 1.5 2.8 7.7 0.2 2.4 2 0 0 2 2 2 0 Zinc Finger domain adh_short_C2 PF13561.6 OAJ30199.1 - 6.9e-54 182.9 1.9 1e-53 182.3 1.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ30199.1 - 1.7e-43 148.4 0.5 2.3e-43 147.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ30199.1 - 5.6e-10 39.4 3.8 1.2e-09 38.4 1.4 2.4 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 OAJ30199.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HSBP1 PF06825.12 OAJ30202.1 - 1.1e-14 54.0 0.4 1.4e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 WD40 PF00400.32 OAJ30203.1 - 1.4e-07 32.0 3.5 0.0057 17.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 OAJ30203.1 - 6.4e-06 25.9 0.1 1.7e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain HAD_2 PF13419.6 OAJ30203.1 - 6.7e-05 23.0 0.1 0.00013 22.2 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase F-box-like PF12937.7 OAJ30203.1 - 0.00027 20.7 0.1 0.00065 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF2608 PF11019.8 OAJ30203.1 - 0.0019 17.8 0.0 0.0092 15.5 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2608) Hydrolase PF00702.26 OAJ30203.1 - 0.004 17.5 0.1 0.06 13.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nup160 PF11715.8 OAJ30203.1 - 0.055 12.1 0.5 0.13 10.9 0.0 1.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 COesterase PF00135.28 OAJ30204.1 - 1.7e-96 324.1 0.0 2.2e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ30204.1 - 2.3e-09 37.4 0.5 2.2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Vps39_2 PF10367.9 OAJ30205.1 - 5.7e-06 26.7 2.1 1.4e-05 25.5 2.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAJ30205.1 - 1e-05 25.3 0.0 4.7e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 OAJ30205.1 - 0.064 13.6 0.5 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Spt20 PF12090.8 OAJ30205.1 - 0.31 10.6 4.5 0.49 10.0 4.5 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 OAJ30205.1 - 0.35 11.0 7.1 0.85 9.7 7.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_14 PF13428.6 OAJ30205.1 - 3.9 8.6 11.0 72 4.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 OAJ30206.1 - 2.3e-47 161.1 0.2 3.1e-47 160.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FleQ PF06490.11 OAJ30206.1 - 0.082 13.3 0.0 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ UPF0270 PF06794.12 OAJ30206.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) HAD PF12710.7 OAJ30207.1 - 4.4e-21 76.2 0.0 5.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 OAJ30207.1 - 4.3e-06 26.4 0.0 2.2e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 OAJ30207.1 - 0.00015 21.3 0.3 0.0014 18.1 0.1 2.0 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.26 OAJ30207.1 - 0.00081 19.7 0.7 0.014 15.7 0.0 2.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 OAJ30208.1 - 3.9e-64 216.6 0.0 3.9e-64 216.6 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30208.1 - 2.7e-43 148.1 0.3 7.3e-43 146.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30208.1 - 1.7e-06 27.5 0.0 2.7e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like HNOBA PF07701.14 OAJ30208.1 - 0.008 15.6 0.9 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 Heme NO binding associated Pkinase_fungal PF17667.1 OAJ30208.1 - 0.043 12.6 0.0 0.043 12.6 0.0 3.4 3 0 0 3 3 3 0 Fungal protein kinase Spt20 PF12090.8 OAJ30208.1 - 0.13 11.9 61.5 0.53 9.9 17.6 2.6 2 0 0 2 2 2 0 Spt20 family DUF4770 PF15994.5 OAJ30208.1 - 1.7 8.8 19.2 0.84 9.9 6.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Spore_YhcN_YlaJ PF09580.10 OAJ30208.1 - 3.6 7.6 20.4 0.24 11.5 2.3 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) p450 PF00067.22 OAJ30210.1 - 2.2e-49 168.5 0.0 4.5e-48 164.2 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 Pyridoxal_deC PF00282.19 OAJ30211.1 - 1.1e-65 221.8 0.0 1.6e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 OAJ30211.1 - 0.0082 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pil1 PF13805.6 OAJ30212.1 - 1e-33 117.0 0.2 1e-33 117.0 0.2 1.9 2 0 0 2 2 2 1 Eisosome component PIL1 FUSC PF04632.12 OAJ30212.1 - 0.0034 16.0 0.9 0.0057 15.3 0.9 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Roughex PF06020.11 OAJ30212.1 - 0.012 14.7 0.5 0.012 14.7 0.5 1.7 2 0 0 2 2 2 0 Drosophila roughex protein SUIM_assoc PF16619.5 OAJ30212.1 - 0.085 12.9 16.3 2 8.6 9.2 3.7 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1664 PF07889.12 OAJ30212.1 - 0.095 12.7 0.2 0.24 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAJ30212.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.7 3 0 0 3 3 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 OAJ30212.1 - 0.11 12.6 0.2 0.11 12.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 OAJ30212.1 - 0.15 12.1 1.3 0.32 11.1 1.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor GrpE PF01025.19 OAJ30212.1 - 3.9 7.1 6.5 0.16 11.6 0.3 2.0 2 1 0 2 2 2 0 GrpE TBCC_N PF16752.5 OAJ30212.1 - 6.2 7.3 9.6 0.29 11.6 0.3 2.6 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain TFIIA PF03153.13 OAJ30212.1 - 7.6 6.4 26.5 0.098 12.6 15.3 2.4 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GMP_synt_C PF00958.22 OAJ30213.1 - 1.1e-43 147.2 0.0 2e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 OAJ30213.1 - 2.1e-36 125.5 0.0 3.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 OAJ30213.1 - 7.6e-11 41.6 0.1 1.4e-06 27.6 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 OAJ30213.1 - 1.4e-08 34.8 0.0 3.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 OAJ30213.1 - 0.00057 18.8 0.2 0.001 17.9 0.2 1.4 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 OAJ30213.1 - 0.0038 16.8 0.0 0.0076 15.9 0.0 1.5 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 OAJ30213.1 - 0.017 14.7 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 OAJ30213.1 - 0.073 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 OAJ30213.1 - 0.097 12.4 0.2 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 PP-loop family RA PF00788.23 OAJ30215.1 - 5.1e-11 43.1 4.5 1.5e-09 38.3 0.0 3.4 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 OAJ30215.1 - 4.7e-07 29.3 0.0 9.9e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Med15 PF09606.10 OAJ30215.1 - 0.0015 17.3 30.3 0.0015 17.3 30.3 3.5 3 1 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal SH3_9 PF14604.6 OAJ30215.1 - 0.0083 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MRI PF15325.6 OAJ30216.1 - 0.43 11.7 5.5 0.55 11.3 5.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection CCDC106 PF15794.5 OAJ30216.1 - 0.66 9.6 4.7 0.7 9.6 4.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 MGC-24 PF05283.11 OAJ30217.1 - 3.3 8.2 16.6 6.6 7.2 16.6 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SRP54 PF00448.22 OAJ30218.1 - 1.4e-74 250.0 0.3 1.4e-74 250.0 0.3 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 OAJ30218.1 - 1.6e-28 99.2 0.1 1.6e-28 99.2 0.1 3.5 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 OAJ30218.1 - 2.7e-16 59.6 2.2 5.5e-16 58.5 2.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 OAJ30218.1 - 0.00014 21.5 0.8 0.002 17.8 0.8 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 OAJ30218.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ30218.1 - 0.0057 17.1 0.0 0.0057 17.1 0.0 2.6 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.20 OAJ30218.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 OAJ30218.1 - 0.032 14.5 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 OAJ30218.1 - 0.046 14.1 1.0 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 OAJ30218.1 - 0.084 12.6 0.1 0.084 12.6 0.1 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 OAJ30218.1 - 0.1 12.7 0.1 0.44 10.6 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 OAJ30218.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.21 OAJ30218.1 - 0.16 11.4 0.2 1.3 8.4 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 OAJ30218.1 - 0.16 12.5 0.0 0.41 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 OAJ30218.1 - 0.21 11.6 0.6 2.8 7.9 0.6 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 OAJ30218.1 - 0.22 11.1 1.5 0.85 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain Tox-REase-3 PF15647.6 OAJ30218.1 - 0.44 10.9 2.8 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 CALM_bind PF16025.5 OAJ30218.1 - 8.6 6.9 7.2 5.5 7.5 0.6 3.2 3 0 0 3 3 3 0 Calcium-dependent calmodulin binding Lipase_chap PF03280.14 OAJ30218.1 - 9.7 6.1 8.7 1.6 8.7 0.2 2.8 3 0 0 3 3 3 0 Proteobacterial lipase chaperone protein FAD_binding_7 PF03441.14 OAJ30219.1 - 1.6e-54 184.4 1.0 2.6e-54 183.8 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 OAJ30219.1 - 2.4e-19 70.0 0.0 4.1e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase HSA PF07529.13 OAJ30220.1 - 4.2e-12 46.2 2.9 4.2e-12 46.2 2.9 4.7 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 OAJ30220.1 - 4.5e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 OAJ30220.1 - 0.0036 17.5 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ30220.1 - 0.034 14.3 0.2 0.034 14.3 0.2 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Prefoldin PF02996.17 OAJ30221.1 - 1.4e-26 92.7 0.1 1.8e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 OAJ30221.1 - 0.018 15.0 0.2 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1192 PF06698.11 OAJ30221.1 - 0.038 14.0 2.8 0.27 11.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1664 PF07889.12 OAJ30221.1 - 0.046 13.8 0.2 4.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nas2_N PF18265.1 OAJ30221.1 - 0.15 12.0 0.5 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Nas2 N_terminal domain GAS PF13851.6 OAJ30221.1 - 0.16 11.3 2.6 2.4 7.5 0.6 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GATA PF00320.27 OAJ30222.1 - 1.3e-26 91.9 21.2 5.1e-14 51.6 4.7 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 OAJ30222.1 - 4.1e-09 36.1 0.3 7.4e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 OAJ30222.1 - 0.0022 17.5 7.2 0.049 13.1 1.5 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 OAJ30222.1 - 0.2 11.7 6.8 4.2 7.5 7.1 2.6 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 OAJ30222.1 - 0.3 11.2 7.1 0.67 10.1 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 OAJ30222.1 - 0.45 10.5 7.8 6.1 6.9 0.7 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 OAJ30222.1 - 1.7 8.9 11.4 0.61 10.3 0.6 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-piccolo PF05715.13 OAJ30222.1 - 2.6 8.3 11.5 3.1 8.0 1.3 3.4 2 1 1 3 3 3 0 Piccolo Zn-finger eIF-5_eIF-2B PF01873.17 OAJ30222.1 - 7.1 6.5 9.6 2.7 7.9 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ubiquitin PF00240.23 OAJ30223.1 - 6.7e-34 115.5 0.7 9.4e-34 115.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 OAJ30223.1 - 4.7e-16 58.4 0.8 7.2e-16 57.8 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 OAJ30223.1 - 5.9e-10 39.1 5.5 1e-09 38.4 5.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 OAJ30223.1 - 3.2e-05 24.3 0.2 0.00012 22.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ30223.1 - 0.0033 17.5 0.4 0.014 15.5 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ30223.1 - 0.0061 16.5 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ30223.1 - 0.0072 16.7 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 OAJ30223.1 - 0.019 15.5 0.1 0.024 15.2 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ30223.1 - 0.023 14.7 1.1 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ30223.1 - 0.096 12.5 0.9 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Pet191_N PF10203.9 OAJ30224.1 - 2.9e-24 85.1 2.6 3.4e-24 84.9 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CCT PF06203.14 OAJ30224.1 - 0.063 13.3 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 CCT motif Lysine_decarbox PF03641.14 OAJ30225.1 - 7.3e-33 113.5 0.0 9.6e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 OAJ30225.1 - 3.2e-10 39.8 2.1 8.6e-10 38.4 2.1 1.8 1 1 0 1 1 1 1 SLOG cluster4 family HMG-CoA_red PF00368.18 OAJ30226.1 - 7.3e-140 466.1 8.6 1.1e-139 465.6 8.6 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 OAJ30226.1 - 5.2e-20 71.8 1.0 1.3e-09 38.1 0.2 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 OAJ30226.1 - 9.6e-06 24.0 2.9 0.0012 17.0 0.0 2.2 2 0 0 2 2 2 2 Patched family HPIH PF13323.6 OAJ30226.1 - 2.2 8.1 6.4 0.15 11.9 0.3 2.2 3 0 0 3 3 3 0 N-terminal domain with HPIH motif ANAPC4_WD40 PF12894.7 OAJ30227.1 - 4.9e-08 33.2 0.0 0.039 14.3 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ30227.1 - 5.8e-05 23.8 4.2 24 6.0 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_2 PF13360.6 OAJ30227.1 - 0.0064 16.1 0.0 0.025 14.2 0.0 1.9 3 0 0 3 3 3 1 PQQ-like domain Abhydrolase_1 PF00561.20 OAJ30228.1 - 3.1e-20 72.9 0.3 3.7e-17 62.8 0.1 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ30228.1 - 7.1e-13 48.6 0.0 1.7e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF1729 PF08354.10 OAJ30229.1 - 8e-77 258.5 1.0 1.2e-53 182.3 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1729) DUF1729 PF08354.10 OAJ30230.1 - 7.7e-28 97.4 0.1 9.2e-28 97.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) AhpC-TSA PF00578.21 OAJ30232.1 - 1.3e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 OAJ30232.1 - 5.9e-05 23.2 0.1 9.7e-05 22.5 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 OAJ30232.1 - 0.00019 21.2 0.0 0.00085 19.1 0.0 1.8 2 0 0 2 2 2 1 Redoxin EamA PF00892.20 OAJ30233.1 - 1e-20 74.3 36.5 1e-12 48.4 10.8 3.6 2 2 1 3 3 3 3 EamA-like transporter family PBP_N PF17093.5 OAJ30233.1 - 0.0046 17.2 0.3 0.0046 17.2 0.3 2.6 3 0 0 3 3 3 1 Penicillin-binding protein N-terminus Nuc_sug_transp PF04142.15 OAJ30233.1 - 0.084 12.0 1.0 0.19 10.8 1.0 1.5 1 0 0 1 1 1 0 Nucleotide-sugar transporter TPT PF03151.16 OAJ30233.1 - 0.13 11.6 5.4 2.8 7.2 0.6 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family AA_permease PF00324.21 OAJ30234.1 - 2.4e-108 362.8 26.9 2.9e-108 362.5 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ30234.1 - 2.4e-35 122.2 29.8 3e-35 121.9 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease Apolipoprotein PF01442.18 OAJ30237.1 - 0.014 15.3 2.8 0.095 12.6 0.7 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain SGP PF17228.2 OAJ30238.1 - 1 10.2 12.5 2.5 9.0 12.5 1.6 1 0 0 1 1 1 0 Sulphur globule protein DNA_pol_phi PF04931.13 OAJ30238.1 - 1.6 6.7 8.6 2.8 5.9 8.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi HSP70 PF00012.20 OAJ30240.1 - 1.2e-27 96.4 0.1 1.8e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein RNA_pol_I_A49 PF06870.12 OAJ30240.1 - 3.4e-11 42.6 0.1 5.3e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_U40 PF10464.9 OAJ30240.1 - 0.057 13.1 0.1 0.092 12.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 FAS_I_H PF18314.1 OAJ30241.1 - 0.041 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain NDC10_II PF16787.5 OAJ30242.1 - 1.3e-46 159.2 0.0 2.1e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HTH_29 PF13551.6 OAJ30242.1 - 0.061 13.4 0.8 3.9 7.6 0.0 3.6 4 0 0 4 4 4 0 Winged helix-turn helix DASH_Hsk3 PF08227.11 OAJ30242.1 - 0.063 13.6 0.1 0.2 12.1 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF3818 PF12825.7 OAJ30244.1 - 1.6e-128 428.5 0.0 2.3e-128 428.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PX PF00787.24 OAJ30244.1 - 0.0039 17.2 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 PX domain MnmE_helical PF12631.7 OAJ30244.1 - 0.03 14.5 0.0 5.7 7.0 0.0 3.6 2 1 0 3 3 3 0 MnmE helical domain Methyltransf_31 PF13847.6 OAJ30245.1 - 5.8e-07 29.4 0.0 8.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 OAJ30245.1 - 3.4e-06 26.6 0.0 4.2e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 OAJ30245.1 - 9.4e-06 26.3 0.0 2.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 OAJ30245.1 - 0.00011 21.8 0.9 0.01 15.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 OAJ30245.1 - 0.0057 16.5 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 OAJ30245.1 - 0.011 15.1 0.1 0.025 14.0 0.1 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 OAJ30245.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_10 PF05971.12 OAJ30245.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_15 PF09445.10 OAJ30245.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 OAJ30245.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 OAJ30245.1 - 0.14 12.9 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ30245.1 - 0.16 12.7 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Vps16_C PF04840.12 OAJ30246.1 - 3.5e-70 236.6 1.7 6.1e-38 130.7 0.0 3.1 3 0 0 3 3 3 3 Vps16, C-terminal region Vps16_N PF04841.13 OAJ30246.1 - 4.1e-47 160.9 0.0 1.5e-20 73.4 0.0 4.2 4 0 0 4 4 4 4 Vps16, N-terminal region Nop10p PF04135.12 OAJ30246.1 - 1.5e-20 72.9 1.6 1.3e-19 69.9 0.3 2.8 3 0 0 3 3 3 1 Nucleolar RNA-binding protein, Nop10p family PseudoU_synth_1 PF01416.20 OAJ30248.1 - 6.3e-24 84.5 0.3 2.7e-20 72.8 0.1 3.5 3 1 0 3 3 3 2 tRNA pseudouridine synthase TT_ORF2 PF02957.15 OAJ30248.1 - 4.9 8.1 6.3 8 7.4 0.7 2.9 2 0 0 2 2 2 0 TT viral ORF2 LSPR PF06049.12 OAJ30249.1 - 5.8 7.2 5.7 74 3.8 0.4 3.7 1 1 1 2 2 2 0 Coagulation Factor V LSPD Repeat KRAB PF01352.27 OAJ30250.1 - 0.22 11.2 0.7 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 KRAB box VIR_N PF15912.5 OAJ30250.1 - 0.64 9.6 0.0 0.64 9.6 0.0 3.1 2 1 0 2 2 2 0 Virilizer, N-terminal WLM PF08325.10 OAJ30251.1 - 4.2e-47 160.7 0.0 1e-46 159.4 0.0 1.7 2 0 0 2 2 2 1 WLM domain YL1 PF05764.13 OAJ30252.1 - 0.44 10.6 17.3 0.042 14.0 7.9 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Casc1 PF12366.8 OAJ30252.1 - 8.4 5.8 9.5 5.8 6.4 1.0 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Metallophos PF00149.28 OAJ30253.1 - 1.5e-08 35.4 1.5 2.5e-08 34.7 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Myc_target_1 PF15179.6 OAJ30253.1 - 0.19 11.6 3.8 0.36 10.7 3.8 1.3 1 0 0 1 1 1 0 Myc target protein 1 CBF PF03914.17 OAJ30254.1 - 9.7e-23 81.0 0.1 3.9e-22 79.1 0.1 2.1 1 0 0 1 1 1 1 CBF/Mak21 family AIM5 PF17050.5 OAJ30254.1 - 0.013 16.3 0.4 0.075 13.9 0.1 2.5 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 Sas10_Utp3 PF04000.15 OAJ30255.1 - 3.7e-08 33.9 0.4 1e-07 32.5 0.4 1.8 1 1 0 1 1 1 1 Sas10/Utp3/C1D family TMEM51 PF15345.6 OAJ30255.1 - 0.037 13.9 0.1 0.096 12.5 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 Actino_peptide PF14408.6 OAJ30255.1 - 0.15 12.2 4.2 0.21 11.7 0.9 2.7 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes HIRAN PF08797.11 OAJ30256.1 - 3.1e-19 68.7 0.0 5.5e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain Ribosomal_L23eN PF03939.13 OAJ30256.1 - 0.019 15.2 5.3 0.042 14.0 5.3 1.6 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain SPT6_acidic PF14632.6 OAJ30256.1 - 7.8 7.2 24.6 9.1 6.9 1.1 3.9 3 1 1 4 4 4 0 Acidic N-terminal SPT6 Spt5_N PF11942.8 OAJ30256.1 - 8.7 7.4 20.2 2.6 9.1 3.8 4.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Acetyltransf_1 PF00583.25 OAJ30257.1 - 1.4e-06 28.5 0.0 0.0028 17.9 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ30257.1 - 1.8e-05 25.1 0.0 3.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ30257.1 - 7.1e-05 22.7 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ30257.1 - 0.047 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 OAJ30257.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ30257.1 - 0.17 11.9 0.0 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein SDA1 PF05285.12 OAJ30257.1 - 0.19 11.1 24.1 0.21 11.0 4.5 3.2 3 0 0 3 3 3 0 SDA1 Spt5_N PF11942.8 OAJ30257.1 - 0.58 11.2 33.2 0.59 11.1 7.0 4.6 4 0 0 4 4 4 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.12 OAJ30257.1 - 1.6 6.9 21.8 1.4 7.0 6.9 3.1 3 0 0 3 3 3 0 Nop14-like family Mucin PF01456.17 OAJ30257.1 - 9.3 6.2 31.5 0.064 13.3 5.8 3.6 3 0 0 3 3 3 0 Mucin-like glycoprotein PAP2 PF01569.21 OAJ30258.1 - 5e-12 45.7 3.0 5.7e-11 42.3 3.0 2.2 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 OAJ30258.1 - 0.035 14.2 2.1 0.25 11.5 0.1 2.5 2 2 0 2 2 2 0 Divergent PAP2 family DUF2517 PF10725.9 OAJ30258.1 - 0.082 12.7 0.5 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) DUF1768 PF08719.11 OAJ30259.1 - 2.3e-14 54.0 1.4 2e-12 47.6 1.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) GCS PF03074.16 OAJ30260.1 - 6.1e-159 529.2 0.0 7.5e-133 443.4 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase DUF3246 PF11596.8 OAJ30260.1 - 0.47 9.8 2.7 0.91 8.9 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CENP-B_dimeris PF09026.10 OAJ30260.1 - 1.6 9.2 6.5 0.48 10.8 2.7 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAJ30260.1 - 3.1 7.5 6.0 6.6 6.4 6.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 OAJ30260.1 - 7.6 7.0 6.8 29 5.1 6.8 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIE_alpha PF02002.17 OAJ30261.1 - 3.5e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit OSTMP1 PF09777.9 OAJ30261.1 - 0.071 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor TF_Zn_Ribbon PF08271.12 OAJ30261.1 - 0.33 10.5 2.4 0.91 9.1 2.4 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding ADK_lid PF05191.14 OAJ30261.1 - 1.2 9.2 7.4 0.22 11.6 1.9 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-C3HC4_3 PF13920.6 OAJ30262.1 - 0.04 13.8 0.3 0.058 13.3 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 OAJ30263.1 - 1.9e-20 72.9 0.7 4.4e-12 46.3 0.1 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ30263.1 - 5.8e-17 62.1 0.1 6.7e-09 36.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 OAJ30263.1 - 2.7e-14 52.9 0.0 0.00017 21.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 OAJ30263.1 - 9.3e-14 51.3 0.4 1.1e-06 28.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ30263.1 - 4.7e-11 41.9 0.1 0.0049 17.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 OAJ30263.1 - 1e-05 25.3 1.1 9.6e-05 22.2 0.2 2.5 2 1 0 2 2 2 1 KilA-N domain PTPlike_phytase PF14566.6 OAJ30263.1 - 0.16 12.1 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate zf-C3HC4_3 PF13920.6 OAJ30264.1 - 1.4e-08 34.4 7.6 4.6e-08 32.8 7.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ30264.1 - 1.9e-05 24.4 4.2 3.4e-05 23.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ30264.1 - 0.00062 20.0 6.4 0.0015 18.8 6.4 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ30264.1 - 0.0012 18.7 3.8 0.0021 18.0 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ30264.1 - 0.0016 18.2 5.3 0.016 15.1 5.3 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 OAJ30264.1 - 0.0038 17.2 2.8 0.019 15.0 1.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ30264.1 - 0.091 12.6 5.7 0.054 13.3 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 OAJ30264.1 - 1.3 8.9 3.8 3.3 7.6 3.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RIO1 PF01163.22 OAJ30265.1 - 2.3e-38 131.7 0.1 2.4e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 OAJ30265.1 - 7.2e-29 99.8 0.0 1.6e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 OAJ30265.1 - 2.6e-07 30.8 0.8 0.00036 20.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 OAJ30265.1 - 0.0031 16.9 0.0 0.027 13.8 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MarR_2 PF12802.7 OAJ30265.1 - 0.08 12.8 0.3 0.45 10.4 0.2 2.2 2 0 0 2 2 2 0 MarR family Ribosomal_60s PF00428.19 OAJ30265.1 - 0.76 10.4 0.0 0.76 10.4 0.0 4.4 3 1 0 3 3 3 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.8 OAJ30265.1 - 4.3 7.5 40.6 0.099 12.9 15.7 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 SpoIIIAH PF12685.7 OAJ30265.1 - 4.9 6.9 24.0 0.31 10.9 8.2 2.4 3 0 0 3 3 3 0 SpoIIIAH-like protein Epimerase PF01370.21 OAJ30266.1 - 3.1e-15 56.3 0.0 6.8e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 OAJ30266.1 - 6.6e-14 51.6 0.0 3.4e-13 49.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 OAJ30266.1 - 2.6e-09 36.6 0.0 1.4e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 OAJ30266.1 - 4.2e-07 30.0 0.0 6.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 OAJ30266.1 - 4.5e-05 23.0 0.0 0.00015 21.3 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase DUF1490 PF07371.12 OAJ30266.1 - 0.098 12.7 0.3 9.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) RmlD_sub_bind PF04321.17 OAJ30266.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 RmlD substrate binding domain muHD PF10291.9 OAJ30267.1 - 7.7e-37 127.2 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Adap_comp_sub PF00928.21 OAJ30267.1 - 7.9e-06 25.4 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 Adaptor complexes medium subunit family FCH PF00611.23 OAJ30267.1 - 2.5e-05 24.5 0.9 9.3e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain ABC_tran_CTD PF16326.5 OAJ30267.1 - 0.036 14.3 1.1 0.14 12.4 1.1 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain Spc7 PF08317.11 OAJ30267.1 - 0.054 12.4 1.5 0.085 11.7 1.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BCDHK_Adom3 PF10436.9 OAJ30267.1 - 0.17 11.7 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PKcGMP_CC PF16808.5 OAJ30267.1 - 0.3 11.0 1.8 0.27 11.1 0.3 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APG6_N PF17675.1 OAJ30267.1 - 1 9.9 4.0 3.3 8.2 4.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region HrpB7 PF09486.10 OAJ30267.1 - 1 9.7 12.2 0.025 15.0 4.9 2.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) 4F5 PF04419.14 OAJ30269.1 - 2.4e-09 37.9 8.8 2.4e-09 37.9 8.8 2.2 2 0 0 2 2 2 1 4F5 protein family CdhC PF03598.15 OAJ30269.1 - 0.089 12.7 0.0 0.094 12.6 0.0 1.0 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit RPA_C PF08784.11 OAJ30270.1 - 2.2e-09 37.9 0.9 4.8e-09 36.8 0.1 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 OAJ30270.1 - 3.4e-09 36.6 0.1 5.8e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 OAJ30270.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 HTH_20 PF12840.7 OAJ30270.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BOF PF04076.13 OAJ30270.1 - 0.1 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein ABC_tran_CTD PF16326.5 OAJ30271.1 - 0.4 11.0 0.2 0.4 11.0 0.2 2.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain Chs7 PF12271.8 OAJ30272.1 - 1e-44 153.1 15.5 8.1e-36 123.9 9.9 2.0 2 0 0 2 2 2 2 Chitin synthase export chaperone Soyouz_module PF14313.6 OAJ30272.1 - 0.00013 21.6 0.5 0.00068 19.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Paramyxovirinae phosphoprotein (P) PsbX PF06596.11 OAJ30272.1 - 6 6.9 7.8 3.3 7.8 0.2 3.4 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) XPG_I PF00867.18 OAJ30273.1 - 1.1e-15 57.7 0.0 8.6e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 OAJ30273.1 - 5e-06 26.9 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain GEN1_C PF18380.1 OAJ30273.1 - 0.0048 17.8 1.7 0.0048 17.8 1.7 5.6 5 3 0 5 5 5 1 Holliday junction resolvase Gen1 C-terminal domain Ribul_P_3_epim PF00834.19 OAJ30274.1 - 2.5e-67 226.1 0.0 3e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 OAJ30274.1 - 0.0017 18.2 0.0 0.006 16.4 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain BATS PF06968.13 OAJ30274.1 - 0.16 12.1 0.0 7.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain Abhydrolase_3 PF07859.13 OAJ30275.1 - 3.2e-10 40.2 0.0 4.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ30275.1 - 4.3e-09 37.3 2.3 9.5e-09 36.2 2.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ30275.1 - 5.3e-09 35.7 0.4 2e-07 30.5 0.1 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ30275.1 - 2.4e-06 27.4 0.1 4.8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ30275.1 - 0.0089 15.5 0.1 0.072 12.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 OAJ30275.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain MOZART1 PF12554.8 OAJ30276.1 - 2.6e-15 55.9 0.1 3.3e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SelB-wing_2 PF09106.11 OAJ30276.1 - 0.11 12.7 0.2 0.27 11.5 0.0 1.6 1 1 1 2 2 2 0 Elongation factor SelB, winged helix UPF0181 PF03701.14 OAJ30276.1 - 0.16 11.7 0.2 0.34 10.6 0.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0181) Syja_N PF02383.18 OAJ30278.1 - 1.1e-77 261.5 0.0 1.5e-77 261.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 OAJ30278.1 - 3.5e-28 97.6 0.0 1.6e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase FAD_binding_3 PF01494.19 OAJ30279.1 - 1.4e-22 80.5 0.2 3.4e-12 46.3 0.0 3.1 2 2 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ30279.1 - 5.2e-06 26.6 0.0 2.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ30279.1 - 7.9e-06 25.7 0.0 2.4e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 OAJ30279.1 - 0.00047 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ30279.1 - 0.00051 19.4 0.0 0.00099 18.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 OAJ30279.1 - 0.0011 18.0 0.0 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase HI0933_like PF03486.14 OAJ30279.1 - 0.0013 17.5 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 OAJ30279.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 OAJ30279.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 OAJ30279.1 - 0.0051 15.9 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 OAJ30279.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 OAJ30279.1 - 0.15 10.8 0.0 0.6 8.9 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase MAT1 PF06391.13 OAJ30280.1 - 4.2e-41 141.0 3.8 6.4e-41 140.4 3.8 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 OAJ30280.1 - 3.8e-17 61.9 7.5 5.9e-17 61.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ30280.1 - 0.00019 21.2 8.1 0.00041 20.1 8.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ30280.1 - 0.00021 21.1 2.1 0.00021 21.1 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ30280.1 - 0.0011 19.2 6.7 0.002 18.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 OAJ30280.1 - 0.0019 18.1 8.3 0.0058 16.6 8.6 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 OAJ30280.1 - 0.024 14.4 8.4 0.072 12.9 4.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 OAJ30280.1 - 0.17 11.6 3.5 0.27 10.9 3.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 OAJ30280.1 - 0.38 10.8 7.4 0.74 9.9 7.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-UDP PF14569.6 OAJ30280.1 - 1.1 9.4 5.3 7.3 6.8 1.6 2.3 2 0 0 2 2 2 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.10 OAJ30280.1 - 3.2 8.0 9.9 31 4.8 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_4 PF14447.6 OAJ30280.1 - 3.4 7.6 12.0 12 5.9 12.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Syndecan PF01034.20 OAJ30281.1 - 0.15 12.0 0.5 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Syndecan domain Acetate_kinase PF00871.17 OAJ30283.1 - 1.3e-18 66.9 0.1 7e-12 44.7 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family Acetate_kinase PF00871.17 OAJ30284.1 - 1.8e-31 109.2 0.0 1e-27 96.9 0.0 2.1 2 0 0 2 2 2 2 Acetokinase family CTP_synth_N PF06418.14 OAJ30285.1 - 8.5e-120 399.0 0.0 1.1e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 OAJ30285.1 - 1.4e-47 161.9 0.0 2.7e-37 128.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferase class-I CbiA PF01656.23 OAJ30285.1 - 0.081 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain JmjC PF02373.22 OAJ30286.1 - 1.1e-12 48.4 0.0 2.8e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 OAJ30286.1 - 8.7e-10 38.7 0.0 4.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Cupin-like domain F-box-like PF12937.7 OAJ30286.1 - 0.0013 18.6 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 OAJ30286.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Nop25 PF09805.9 OAJ30287.1 - 3.5e-19 69.6 14.8 3.5e-19 69.6 14.8 2.5 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) CNDH2_C PF16858.5 OAJ30287.1 - 0.14 12.0 10.5 0.23 11.3 10.5 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term ALC PF17527.2 OAJ30287.1 - 1.9 8.1 14.9 0.23 11.1 6.1 2.2 1 1 0 2 2 2 0 Phage ALC protein Methyltransf_23 PF13489.6 OAJ30288.1 - 1.7e-08 34.5 0.0 3.8e-08 33.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ30288.1 - 1.8e-08 35.0 0.0 5.7e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ30288.1 - 4.1e-08 33.8 0.0 1.6e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ30288.1 - 3.9e-06 27.5 0.0 2.4e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ30288.1 - 1.1e-05 25.2 0.0 3.4e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ30288.1 - 0.00012 21.5 0.0 0.00029 20.2 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 OAJ30288.1 - 0.068 12.8 0.2 0.16 11.6 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 OAJ30288.1 - 0.078 12.3 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 OAJ30288.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 OAJ30288.1 - 0.13 11.8 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Glycos_transf_3 PF00591.21 OAJ30289.1 - 1.1e-67 228.3 0.0 1.3e-63 215.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 OAJ30289.1 - 0.0011 18.7 0.5 0.0011 18.7 0.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF5401 PF17380.2 OAJ30289.1 - 9.8 4.1 11.0 13 3.7 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) HIT PF01230.23 OAJ30290.1 - 3.2e-23 82.3 0.0 4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ30290.1 - 1.3e-05 25.7 0.0 1.8e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding NAD_binding_2 PF03446.15 OAJ30291.1 - 6.1e-23 81.7 0.2 9.6e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 OAJ30291.1 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 OAJ30291.1 - 8.1e-08 32.4 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 OAJ30291.1 - 3e-05 24.5 0.1 0.00049 20.6 0.0 2.5 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UvrC_HhH_N PF08459.11 OAJ30291.1 - 0.031 14.2 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF4744 PF15918.5 OAJ30293.1 - 0.042 14.7 0.2 0.21 12.5 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) Helicase_C PF00271.31 OAJ30297.1 - 2.4e-11 44.0 0.0 5.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ30297.1 - 8.3e-08 32.2 0.0 2.1e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DLP_helical PF18709.1 OAJ30297.1 - 0.03 13.5 1.1 0.05 12.8 1.1 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain PSK_trans_fac PF07704.11 OAJ30297.1 - 1.1 10.1 8.7 5.8 7.8 5.5 2.7 2 0 0 2 2 2 0 Rv0623-like transcription factor Dehydrin PF00257.19 OAJ30300.1 - 9.6 6.7 6.5 34 4.9 6.5 1.9 1 0 0 1 1 1 0 Dehydrin MULE PF10551.9 OAJ30301.1 - 9.2e-21 74.1 0.0 2.1e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain DBD_Tnp_Mut PF03108.15 OAJ30301.1 - 4.4e-07 29.8 0.1 9.5e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 MuDR family transposase SWIM PF04434.17 OAJ30301.1 - 5.2e-06 26.0 0.1 1.5e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger Transposase_mut PF00872.18 OAJ30301.1 - 0.00037 19.5 0.0 0.00055 18.9 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family Molybdopterin PF00384.22 OAJ30301.1 - 0.069 12.1 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Mic1 PF07035.12 OAJ30302.1 - 0.24 11.1 6.2 1.2 8.8 0.7 2.1 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Gly_radical PF01228.21 OAJ30302.1 - 0.72 10.4 4.8 0.6 10.7 0.9 2.2 2 0 0 2 2 2 0 Glycine radical Keratin_2_head PF16208.5 OAJ30302.1 - 7.9 6.6 16.4 0.7 10.0 9.8 2.1 2 0 0 2 2 2 0 Keratin type II head DUF1768 PF08719.11 OAJ30304.1 - 5.4e-20 72.3 0.0 7.7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF2353 PF09789.9 OAJ30305.1 - 0.018 14.4 0.1 0.024 14.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Proteasome PF00227.26 OAJ30307.1 - 4.5e-46 156.7 0.4 5.1e-43 146.8 0.1 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 OAJ30307.1 - 4.1e-14 51.9 0.1 7.7e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PH_14 PF17787.1 OAJ30307.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 PH domain Ribophorin_II PF05817.14 OAJ30307.1 - 0.028 13.0 0.6 0.033 12.8 0.0 1.4 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II RNA_ligase PF09414.10 OAJ30308.1 - 3e-23 82.9 0.0 5.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 OAJ30308.1 - 2.5e-10 40.6 0.0 1.1e-07 32.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain Y_phosphatase PF00102.27 OAJ30308.1 - 1.7e-06 27.7 0.0 8.8e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 OAJ30308.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 OAJ30308.1 - 0.0039 17.2 0.5 0.013 15.5 0.5 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family IstB_IS21 PF01695.17 OAJ30308.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAJ30308.1 - 0.035 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DSPc PF00782.20 OAJ30308.1 - 0.043 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Zeta_toxin PF06414.12 OAJ30308.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 OAJ30308.1 - 0.11 12.0 0.2 2.2 7.6 0.2 2.2 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 OAJ30308.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 OAJ30308.1 - 0.15 12.6 0.0 2.2 8.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ30308.1 - 0.19 12.2 0.0 0.46 11.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zn_clus PF00172.18 OAJ30309.1 - 1.3e-06 28.4 9.6 1.3e-06 28.4 9.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.10 OAJ30309.1 - 1.1 9.6 17.6 4.2 7.8 17.6 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Torus PF16131.5 OAJ30310.1 - 1.4e-06 28.9 0.0 4.1e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 OAJ30310.1 - 6.3e-06 26.1 3.1 1.8e-05 24.6 3.1 1.9 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 OAJ30310.1 - 6.5e-06 25.9 0.0 4.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ30310.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 OAJ30310.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 FYVE PF01363.21 OAJ30310.1 - 0.012 15.8 1.5 0.015 15.4 0.2 1.9 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_3 PF15663.5 OAJ30310.1 - 0.013 15.8 0.1 0.037 14.2 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH PF00642.24 OAJ30310.1 - 0.037 13.9 1.2 0.037 13.9 1.2 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 OAJ30310.1 - 3 8.4 5.6 0.94 10.0 2.3 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RXT2_N PF08595.11 OAJ30312.1 - 0.035 14.1 0.0 0.035 14.1 0.0 4.4 5 1 0 5 5 5 0 RXT2-like, N-terminal MA3 PF02847.17 OAJ30313.1 - 2.6e-29 101.5 0.3 4.4e-29 100.8 0.3 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 OAJ30313.1 - 2.5e-09 37.1 0.6 3.5e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 MIF4G domain DUF5523 PF17661.1 OAJ30313.1 - 0.22 11.2 6.6 1.2 8.8 4.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) GCIP PF13324.6 OAJ30313.1 - 0.92 9.1 5.0 1.8 8.1 5.0 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4692 PF15763.5 OAJ30313.1 - 7.3 7.0 6.3 29 5.1 6.3 2.0 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Mucin PF01456.17 OAJ30314.1 - 6.1 6.8 19.2 6.5 6.7 19.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.16 OAJ30315.1 - 5.5e-08 32.1 22.4 5.5e-08 32.1 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SirB PF04247.12 OAJ30315.1 - 1.1 9.4 7.2 8.2 6.5 0.8 3.6 2 1 0 3 3 3 0 Invasion gene expression up-regulator, SirB MBOAT_2 PF13813.6 OAJ30316.1 - 2.1e-05 24.7 1.8 0.0026 18.0 0.3 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family PGA2 PF07543.12 OAJ30316.1 - 0.009 16.0 4.8 0.014 15.3 4.8 1.2 1 0 0 1 1 1 1 Protein trafficking PGA2 KilA-N PF04383.13 OAJ30317.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 KilA-N domain TPR_1 PF00515.28 OAJ30318.1 - 5.9e-09 35.4 0.2 3.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ30318.1 - 1.2e-05 25.1 0.3 0.2 11.8 0.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 OAJ30318.1 - 0.0016 18.5 0.2 0.0073 16.4 0.1 2.2 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 OAJ30318.1 - 0.015 15.5 1.1 1.6 9.0 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ30318.1 - 0.038 14.4 0.1 3.7 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ30318.1 - 0.13 12.4 0.4 2.5 8.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ30318.1 - 0.14 13.1 0.8 44 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 OAJ30319.1 - 2.8e-45 154.2 0.0 5.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ30319.1 - 1.2e-31 109.3 0.0 2.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAJ30319.1 - 0.0059 15.4 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 OAJ30319.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Abhydrolase_1 PF00561.20 OAJ30320.1 - 2.6e-21 76.4 0.0 8.8e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ30320.1 - 4.9e-14 52.3 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 OAJ30320.1 - 0.067 12.5 0.0 3.6 6.8 0.0 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Erp_C PF06780.11 OAJ30320.1 - 0.18 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Erp protein C-terminus Aa_trans PF01490.18 OAJ30322.1 - 4.1e-82 276.1 32.2 5.1e-82 275.8 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PTPRCAP PF15713.5 OAJ30322.1 - 0.00071 19.9 0.5 0.0012 19.1 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Ctr PF04145.15 OAJ30322.1 - 0.0073 16.9 0.0 0.44 11.2 0.0 2.7 2 0 0 2 2 2 1 Ctr copper transporter family FAM176 PF14851.6 OAJ30322.1 - 0.39 10.4 1.1 0.8 9.4 1.1 1.5 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OAJ30322.1 - 1.6 6.9 3.1 2.3 6.4 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ30322.1 - 1.9 7.7 4.4 2.7 7.2 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.9 OAJ30323.1 - 4e-05 23.8 26.4 0.00014 22.0 26.4 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 OAJ30323.1 - 0.006 16.7 4.9 0.01 15.9 4.9 1.4 1 0 0 1 1 1 1 CHCH domain RskA PF10099.9 OAJ30323.1 - 0.037 14.3 10.2 0.046 14.0 10.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Utp21 PF04192.12 OAJ30323.1 - 0.069 12.6 0.0 0.072 12.6 0.0 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain CX9C PF16860.5 OAJ30323.1 - 0.093 12.8 1.7 0.16 12.0 1.7 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 OAJ30323.1 - 0.35 10.9 2.3 18 5.4 0.1 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 OAJ30323.1 - 0.35 11.3 2.7 1.9 8.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) CDC14 PF08045.11 OAJ30324.1 - 3.5e-08 32.9 3.7 0.0016 17.6 1.2 2.8 2 1 0 2 2 2 2 Cell division control protein 14, SIN component zf-CCHC_3 PF13917.6 OAJ30324.1 - 8.2e-07 28.9 5.8 9.6e-07 28.7 3.9 2.2 2 0 0 2 2 2 1 Zinc knuckle SKG6 PF08693.10 OAJ30325.1 - 2.2e-10 39.8 1.6 2.2e-10 39.8 1.6 2.6 2 0 0 2 2 2 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 OAJ30325.1 - 0.00064 19.6 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 TMEM154 protein family SARAF PF06682.12 OAJ30325.1 - 0.0024 17.6 4.2 0.0024 17.6 4.2 3.2 3 1 0 3 3 3 1 SOCE-associated regulatory factor of calcium homoeostasis Adeno_E3_CR2 PF02439.15 OAJ30325.1 - 0.012 15.4 1.1 0.029 14.1 1.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 OAJ30325.1 - 0.033 14.1 0.4 0.063 13.2 0.0 1.5 2 0 0 2 2 2 0 Rifin CD99L2 PF12301.8 OAJ30325.1 - 0.035 14.4 0.2 0.035 14.4 0.2 3.0 2 1 0 2 2 2 0 CD99 antigen like protein 2 DUF4448 PF14610.6 OAJ30325.1 - 0.049 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2627 PF11118.8 OAJ30325.1 - 0.078 13.6 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Zn_clus PF00172.18 OAJ30327.1 - 0.00012 22.1 15.3 0.00023 21.2 15.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aconitase PF00330.20 OAJ30328.1 - 1.1e-111 374.1 0.0 1.1e-110 370.8 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 OAJ30328.1 - 3.5e-21 75.9 0.0 1e-20 74.4 0.0 1.8 1 1 1 2 2 2 1 Aconitase C-terminal domain Sedlin_N PF04628.13 OAJ30329.1 - 3.2e-19 69.3 0.0 1.1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Adeno_PIX PF03955.14 OAJ30329.1 - 0.069 13.3 8.0 0.1 12.7 0.5 2.9 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) ELO PF01151.18 OAJ30330.1 - 5.9e-55 186.5 9.7 7.4e-55 186.2 9.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Dimer_Tnp_hAT PF05699.14 OAJ30332.1 - 2.6e-14 52.8 0.0 4.8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Endonuc-FokI_C PF09254.11 OAJ30332.1 - 0.17 11.2 0.7 0.33 10.2 0.7 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal CCDC106 PF15794.5 OAJ30332.1 - 1 9.0 7.7 3.7 7.2 7.7 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 OAJ30332.1 - 5 5.3 11.7 11 4.2 11.7 1.5 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 OAJ30333.1 - 2.8e-41 141.7 0.0 4.1e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30333.1 - 6.2e-20 71.6 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30333.1 - 5e-05 22.8 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ30333.1 - 0.00077 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RTC4 PF14474.6 OAJ30333.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.5 1 1 0 1 1 1 1 RTC4-like domain Pox_ser-thr_kin PF05445.11 OAJ30333.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NIF PF03031.18 OAJ30333.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase RIO1 PF01163.22 OAJ30333.1 - 0.21 11.2 0.2 0.62 9.6 0.2 1.8 1 1 0 1 1 1 0 RIO1 family Csm1_B PF18211.1 OAJ30334.1 - 0.0091 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Csm1 subunit domain B Helo_like_N PF17111.5 OAJ30334.1 - 0.075 12.4 1.4 2.9 7.2 0.3 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF1948 PF09185.10 OAJ30334.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Latarcin PF10279.9 OAJ30334.1 - 2.9 8.3 8.3 0.71 10.3 3.5 2.4 2 1 0 2 2 2 0 Latarcin precursor Sde2_N_Ubi PF13019.6 OAJ30336.1 - 1.3e-39 135.7 1.4 2.2e-39 134.9 0.0 1.9 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF755 PF05501.11 OAJ30336.1 - 3.1 8.1 10.7 5.5 7.3 10.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Rotamase PF00639.21 OAJ30336.1 - 8.5 7.4 7.1 0.83 10.7 0.7 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain PCI PF01399.27 OAJ30337.1 - 2.5e-15 56.9 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 PCI domain FeoC PF09012.10 OAJ30337.1 - 0.00016 21.6 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 FeoC like transcriptional regulator Aha1_N PF09229.11 OAJ30338.1 - 2.4e-29 102.3 0.0 3.7e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 OAJ30338.1 - 8.2e-17 61.6 0.0 1.6e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Sporozoite_P67 PF05642.11 OAJ30338.1 - 0.27 9.3 8.4 0.34 8.9 8.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MAGE_N PF12440.8 OAJ30338.1 - 0.49 11.1 13.9 1.3 9.7 13.9 1.8 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal VHS PF00790.19 OAJ30339.1 - 2.5e-32 111.6 0.0 5.5e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 OAJ30339.1 - 6.4e-15 54.5 0.1 1.1e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ30339.1 - 1e-13 50.9 0.3 1.8e-13 50.1 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ30339.1 - 1.4e-10 40.7 0.2 2.4e-10 39.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 OAJ30339.1 - 8.3e-08 32.4 1.5 1.4e-07 31.8 0.3 2.0 2 0 0 2 2 2 1 GAT domain HEPN_AbiU2 PF18734.1 OAJ30339.1 - 0.001 18.6 0.9 0.0021 17.6 0.9 1.5 1 0 0 1 1 1 1 AbiU2 Hrs_helical PF12210.8 OAJ30339.1 - 0.017 15.7 0.2 0.057 14.0 0.2 1.9 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Med26 PF08711.11 OAJ30339.1 - 0.16 12.1 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain TTSSLRR PF12468.8 OAJ30339.1 - 0.47 10.7 4.2 1.8 8.9 4.2 2.0 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein DUF2015 PF09435.10 OAJ30340.1 - 1.4e-25 89.3 0.0 2e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ammonium_transp PF00909.21 OAJ30341.1 - 1.3e-105 353.4 25.8 1.5e-105 353.2 25.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MRP-S28 PF10213.9 OAJ30342.1 - 1.6e-26 93.2 0.0 8.7e-26 90.8 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein Period_C PF12114.8 OAJ30342.1 - 0.41 10.2 4.9 0.64 9.6 4.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PHD PF00628.29 OAJ30343.1 - 7.8e-08 32.1 7.0 1.6e-07 31.1 7.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ30343.1 - 0.0028 17.2 8.6 0.0052 16.3 8.6 1.4 1 0 0 1 1 1 1 PHD-finger DUF3246 PF11596.8 OAJ30343.1 - 0.053 12.9 0.9 0.53 9.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PHD_4 PF16866.5 OAJ30343.1 - 0.11 12.6 6.4 0.24 11.5 6.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 OAJ30343.1 - 0.14 12.2 3.2 0.27 11.3 3.2 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger Dscam_C PF12355.8 OAJ30343.1 - 0.81 10.7 6.4 0.3 12.1 2.2 2.5 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal HEAT_EZ PF13513.6 OAJ30344.1 - 6.4e-26 90.4 7.2 4.2e-06 27.1 0.0 10.0 10 0 0 10 10 9 5 HEAT-like repeat HEAT PF02985.22 OAJ30344.1 - 3e-20 70.5 8.1 0.00025 21.0 0.1 9.3 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 OAJ30344.1 - 1.8e-18 66.7 12.1 0.0036 17.7 0.1 8.5 4 3 3 7 7 7 6 HEAT repeats UME PF08064.13 OAJ30344.1 - 2.1e-09 37.2 0.0 0.091 12.7 0.0 5.9 4 2 1 5 5 5 2 UME (NUC010) domain MMS19_C PF12460.8 OAJ30344.1 - 4.8e-09 35.8 2.6 0.003 16.7 0.0 5.8 5 2 2 7 7 7 2 RNAPII transcription regulator C-terminal IBN_N PF03810.19 OAJ30344.1 - 8.1e-08 32.1 1.3 2.5e-07 30.5 0.2 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 OAJ30344.1 - 2.6e-07 30.8 0.3 0.013 15.5 0.0 4.7 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 OAJ30344.1 - 3.2e-06 27.7 0.0 0.54 10.9 0.0 5.7 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 OAJ30344.1 - 1.5e-05 23.8 2.0 0.45 9.0 0.0 4.7 3 1 0 3 3 3 2 Adaptin N terminal region CAS_CSE1 PF03378.15 OAJ30344.1 - 2.8e-05 22.8 2.7 0.0044 15.6 0.0 4.0 5 0 0 5 5 5 1 CAS/CSE protein, C-terminus Cohesin_HEAT PF12765.7 OAJ30344.1 - 7.5e-05 22.9 0.1 0.94 9.8 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 OAJ30344.1 - 8.7e-05 22.2 0.0 0.73 9.3 0.0 5.0 5 1 0 5 5 5 1 CLASP N terminal DUF3385 PF11865.8 OAJ30344.1 - 0.00042 20.3 3.1 43 4.0 0.0 6.8 8 1 1 9 9 9 0 Domain of unknown function (DUF3385) BP28CT PF08146.12 OAJ30344.1 - 0.0005 20.0 0.0 0.54 10.1 0.0 4.5 4 0 0 4 4 4 1 BP28CT (NUC211) domain RTP1_C1 PF10363.9 OAJ30344.1 - 0.001 19.2 0.7 25 5.1 0.1 5.2 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 E3_UbLigase_R4 PF13764.6 OAJ30344.1 - 0.11 10.6 0.1 0.19 9.9 0.1 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Arm PF00514.23 OAJ30344.1 - 0.54 10.4 12.8 37 4.6 0.1 7.8 10 0 0 10 10 10 0 Armadillo/beta-catenin-like repeat DUF2237 PF09996.9 OAJ30345.1 - 8.8e-39 132.1 0.1 1.1e-38 131.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) PNRC PF15365.6 OAJ30346.1 - 1.1e-08 34.7 2.0 1.1e-08 34.7 2.0 3.6 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif CENP-K PF11802.8 OAJ30346.1 - 0.092 12.3 3.6 0.13 11.9 3.6 1.1 1 0 0 1 1 1 0 Centromere-associated protein K TFIIF_alpha PF05793.12 OAJ30346.1 - 0.33 9.5 16.3 0.43 9.1 16.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 OAJ30346.1 - 1.4 7.3 21.9 2 6.9 21.9 1.3 1 0 0 1 1 1 0 Macoilin family DER1 PF04511.15 OAJ30347.1 - 4e-31 108.4 1.0 5.3e-31 108.0 1.0 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 OAJ30347.1 - 0.11 12.5 3.0 0.17 11.9 3.0 1.3 1 0 0 1 1 1 0 Rhomboid family zf-CCCH PF00642.24 OAJ30348.1 - 3.3e-09 36.4 2.7 6.2e-09 35.5 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 OAJ30348.1 - 1.4e-07 31.3 5.4 2.3e-07 30.5 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ30348.1 - 2.5e-06 27.4 8.7 4.7e-06 26.5 8.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ30348.1 - 4.6e-06 26.5 8.8 7.5e-06 25.8 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 OAJ30348.1 - 2e-05 24.5 4.4 3.9e-05 23.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 OAJ30348.1 - 2.9e-05 23.8 8.2 5.2e-05 23.0 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ30348.1 - 3e-05 23.8 8.5 5.2e-05 23.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ30348.1 - 8.7e-05 22.8 6.7 0.00016 21.9 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 OAJ30348.1 - 0.00013 22.0 7.6 0.00027 21.0 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OAJ30348.1 - 0.00054 20.0 3.3 0.0013 18.8 3.3 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 OAJ30348.1 - 0.0016 18.2 2.9 0.0039 17.0 2.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-Nse PF11789.8 OAJ30348.1 - 0.037 13.9 2.6 0.067 13.0 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.9 OAJ30348.1 - 0.071 13.7 0.2 0.19 12.3 0.2 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Prok-RING_4 PF14447.6 OAJ30348.1 - 0.074 12.9 5.8 0.14 12.0 5.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 C1_2 PF03107.16 OAJ30348.1 - 0.62 10.4 5.0 2.7 8.4 1.0 2.5 1 1 1 2 2 2 0 C1 domain zf-rbx1 PF12678.7 OAJ30348.1 - 2.3 8.6 5.3 7.1 7.0 5.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Aldedh PF00171.22 OAJ30349.1 - 1.2e-154 515.3 0.0 1.4e-154 515.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Thx PF17070.5 OAJ30349.1 - 0.0014 18.7 0.5 0.0014 18.7 0.5 1.7 2 0 0 2 2 2 1 30S ribosomal protein Thx LuxC PF05893.14 OAJ30349.1 - 0.0028 16.7 0.1 0.0045 16.1 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) V-ATPase_C PF03223.15 OAJ30350.1 - 1.1e-129 433.0 4.1 1.3e-129 432.9 4.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C YscK PF06578.12 OAJ30350.1 - 0.0046 16.5 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 YOP proteins translocation protein K (YscK) S10_plectin PF03501.15 OAJ30351.1 - 8.2e-40 134.8 0.1 1e-39 134.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_S25 PF03297.15 OAJ30352.1 - 1.3e-37 128.0 2.3 1.7e-37 127.7 2.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 OAJ30352.1 - 0.02 14.5 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 OAJ30352.1 - 0.033 14.1 0.2 0.064 13.2 0.1 1.5 2 0 0 2 2 2 0 MarR family CoA_trans PF01144.23 OAJ30352.1 - 0.15 11.4 0.0 0.37 10.1 0.0 1.5 1 1 1 2 2 2 0 Coenzyme A transferase F_bP_aldolase PF01116.20 OAJ30353.1 - 6.6e-95 317.8 0.0 7.5e-95 317.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3818 PF12825.7 OAJ30355.1 - 2.3e-51 174.8 0.0 3.4e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 OAJ30355.1 - 7.7e-23 80.9 0.0 1.3e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 PX-associated RFamide_26RFa PF11109.8 OAJ30356.1 - 0.98 9.9 4.0 14 6.2 1.6 2.5 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 EF1G PF00647.19 OAJ30357.1 - 4.7e-47 158.5 0.3 9e-47 157.6 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 OAJ30357.1 - 2.4e-16 59.8 0.2 1.1e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ30357.1 - 1.7e-12 47.3 0.0 4.3e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ30357.1 - 1.5e-08 34.5 0.0 3.5e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ30357.1 - 8.1e-07 29.2 0.2 3.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 OAJ30357.1 - 3.5e-06 27.3 0.0 6.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ30357.1 - 1.8e-05 24.9 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SRP-alpha_N PF04086.13 OAJ30357.1 - 0.014 15.3 0.5 0.021 14.7 0.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_60s PF00428.19 OAJ30357.1 - 2 9.1 13.1 5.3 7.7 13.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 OAJ30357.1 - 8.4 7.1 8.6 17 6.1 8.6 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RNA_pol PF00940.19 OAJ30358.1 - 2.6e-171 570.0 0.0 3.6e-171 569.6 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 OAJ30358.1 - 9.3e-84 281.7 1.3 9.3e-84 281.7 1.3 1.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal AP3D1 PF06375.11 OAJ30358.1 - 0.0053 17.0 1.4 0.012 15.8 1.4 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 RhoGEF PF00621.20 OAJ30359.1 - 2.2e-35 122.6 0.2 3.2e-35 122.0 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 OAJ30359.1 - 1.7e-31 109.0 0.0 3.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 OAJ30359.1 - 7e-21 74.3 0.2 2e-12 47.2 0.1 2.5 2 0 0 2 2 2 2 CDC24 Calponin PB1 PF00564.24 OAJ30359.1 - 8.6e-10 38.4 0.2 1.6e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 OAJ30359.1 - 0.0035 17.8 0.1 0.016 15.7 0.1 2.1 1 1 0 1 1 1 1 PH domain CPDase PF07823.11 OAJ30360.1 - 1.2e-17 64.2 0.0 2.6e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 OAJ30360.1 - 1.5e-05 24.9 0.1 6.6e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3349 PF11829.8 OAJ30360.1 - 0.086 13.6 0.0 0.22 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HemN_C PF06969.16 OAJ30360.1 - 0.12 12.4 0.1 0.79 9.8 0.1 2.1 1 1 0 1 1 1 0 HemN C-terminal domain zf-primase PF09329.11 OAJ30362.1 - 1.3e-12 47.3 1.8 2.3e-12 46.5 1.8 1.4 1 0 0 1 1 1 1 Primase zinc finger Glyco_hydro_25 PF01183.20 OAJ30363.1 - 1.1e-43 149.4 0.2 1.4e-43 149.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 RVT_1 PF00078.27 OAJ30365.1 - 9.4e-20 71.1 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAJ30365.1 - 1.5e-10 41.5 0.0 7.9e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 OAJ30365.1 - 1.6e-05 25.6 0.1 3.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Clathrin PF00637.20 OAJ30366.1 - 2.8e-27 95.3 0.0 5.9e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-rbx1 PF12678.7 OAJ30366.1 - 0.0086 16.3 0.2 0.0086 16.3 0.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 OAJ30366.1 - 0.023 14.5 0.2 0.048 13.4 0.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger WD40 PF00400.32 OAJ30366.1 - 0.13 13.2 1.1 0.26 12.2 0.1 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Na_trans_assoc PF06512.13 OAJ30366.1 - 1.1 9.5 8.0 1.9 8.7 8.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated zf-RING_2 PF13639.6 OAJ30366.1 - 1.3 9.4 3.5 2.9 8.3 0.3 2.6 2 0 0 2 2 2 0 Ring finger domain OPT PF03169.15 OAJ30367.1 - 5.8e-131 438.1 3.0 8.3e-131 437.6 3.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1754 PF08555.10 OAJ30368.1 - 9.1e-12 45.6 6.0 9.1e-12 45.6 6.0 1.9 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) MCM3AP_GANP PF16769.5 OAJ30368.1 - 0.0071 14.7 2.3 0.0084 14.4 2.3 1.0 1 0 0 1 1 1 1 MCM3AP domain of GANP CAML PF14963.6 OAJ30368.1 - 0.077 13.1 5.8 0.09 12.9 5.8 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand FAM199X PF15814.5 OAJ30368.1 - 0.41 9.6 9.7 0.48 9.4 9.7 1.0 1 0 0 1 1 1 0 Protein family FAM199X NDUF_B4 PF07225.12 OAJ30369.1 - 0.054 13.4 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Nucleoside_tran PF01733.18 OAJ30370.1 - 2.9e-20 72.9 10.3 3.5e-18 66.1 3.9 3.8 2 1 1 3 3 3 2 Nucleoside transporter Med11 PF10280.9 OAJ30370.1 - 0.03 14.8 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Mediator complex protein HemY_N PF07219.13 OAJ30370.1 - 2.4 8.4 0.0 2.4 8.4 0.0 5.2 5 0 0 5 5 5 0 HemY protein N-terminus Ribosomal_L21p PF00829.21 OAJ30371.1 - 2.2e-18 66.4 0.8 2.3e-13 50.3 1.2 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein SAP130_C PF16014.5 OAJ30371.1 - 0.03 13.4 9.5 0.05 12.7 9.5 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus zf-CCHC_6 PF15288.6 OAJ30372.1 - 0.0044 16.8 0.4 0.012 15.4 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle Pkinase PF00069.25 OAJ30373.1 - 1.8e-24 86.5 0.0 2.5e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30373.1 - 9.1e-14 51.4 0.0 1.3e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30373.1 - 0.0011 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like IHABP4_N PF16174.5 OAJ30374.1 - 0.9 10.1 2.6 2.2 8.8 2.6 1.8 1 1 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Glyco_hydro_63 PF03200.16 OAJ30375.1 - 1.9e-161 538.1 0.0 2.1e-160 534.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 OAJ30375.1 - 3.1e-69 233.5 0.5 2.4e-67 227.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 OAJ30375.1 - 4.8e-05 22.4 0.1 6.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Trehalase F-box-like PF12937.7 OAJ30376.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like ARID PF01388.21 OAJ30377.1 - 1.5e-16 60.8 0.0 1.5e-16 60.8 0.0 4.4 4 1 0 4 4 4 1 ARID/BRIGHT DNA binding domain DUF4637 PF15470.6 OAJ30378.1 - 0.0085 15.8 5.6 0.0095 15.7 5.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) FAM176 PF14851.6 OAJ30378.1 - 0.021 14.5 2.5 0.021 14.5 2.5 1.2 1 0 0 1 1 1 0 FAM176 family Utp14 PF04615.13 OAJ30378.1 - 0.091 11.3 4.2 0.086 11.4 4.2 1.0 1 0 0 1 1 1 0 Utp14 protein Sporozoite_P67 PF05642.11 OAJ30378.1 - 0.2 9.7 2.9 0.18 9.9 2.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 OAJ30378.1 - 0.21 10.7 8.4 0.19 10.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 OAJ30378.1 - 0.31 9.1 8.3 0.31 9.1 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 OAJ30378.1 - 0.34 11.3 9.5 0.52 10.7 9.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ30378.1 - 0.83 10.1 14.1 1.2 9.5 14.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 OAJ30378.1 - 0.94 7.6 6.2 0.8 7.8 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ30378.1 - 1.4 7.1 5.0 1.2 7.3 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 OAJ30378.1 - 1.5 8.8 5.7 1.9 8.5 5.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 OAJ30378.1 - 3.4 7.4 6.6 4.5 7.0 6.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Importin_rep_6 PF18829.1 OAJ30378.1 - 3.4 7.8 6.8 4.5 7.4 6.8 1.1 1 0 0 1 1 1 0 Importin repeat 6 WD40 PF00400.32 OAJ30379.1 - 6.1e-11 42.7 17.1 0.046 14.6 0.5 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ30379.1 - 3e-08 33.8 0.1 0.0018 18.5 0.0 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 OAJ30379.1 - 0.005 15.7 0.7 0.2 10.4 0.9 2.5 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1748 PF08520.10 OAJ30380.1 - 2.7e-27 94.4 0.0 3e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Abhydrolase_3 PF07859.13 OAJ30381.1 - 1.7e-23 83.6 0.0 2.1e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 OAJ30381.1 - 0.0022 17.6 0.1 0.0036 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 OAJ30381.1 - 0.0069 16.0 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Glycoprotein_G PF00802.19 OAJ30382.1 - 0.003 17.0 15.1 0.0049 16.3 15.1 1.3 1 0 0 1 1 1 1 Pneumovirus attachment glycoprotein G DUF4894 PF16235.5 OAJ30382.1 - 0.057 13.8 2.7 0.83 10.0 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4894) QueF_N PF14819.6 OAJ30382.1 - 0.17 12.2 1.3 4.7 7.6 0.0 3.0 2 1 1 3 3 3 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term PRKCSH-like PF12999.7 OAJ30383.1 - 9.3e-43 146.0 6.5 9.3e-43 146.0 6.5 2.4 2 1 1 3 3 3 1 Glucosidase II beta subunit-like Ribosomal_S30 PF04758.14 OAJ30383.1 - 1.1e-26 92.8 6.5 1.1e-26 92.8 6.5 2.0 2 0 0 2 2 2 1 Ribosomal protein S30 PRKCSH_1 PF13015.6 OAJ30383.1 - 2.5e-23 82.5 0.1 5.9e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 OAJ30383.1 - 2.8e-09 37.8 1.4 2.8e-09 37.8 1.4 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Effector_1 PF04518.12 OAJ30383.1 - 0.00092 18.4 0.9 0.0015 17.7 0.9 1.3 1 0 0 1 1 1 1 Effector from type III secretion system DUF2968 PF11180.8 OAJ30383.1 - 0.0016 18.1 7.3 0.033 13.8 7.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.9 OAJ30383.1 - 0.0045 15.9 0.4 0.0073 15.2 0.4 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3584 PF12128.8 OAJ30383.1 - 0.11 10.0 6.6 0.014 13.0 2.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.21 OAJ30383.1 - 0.12 12.5 7.1 3 8.0 1.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor HALZ PF02183.18 OAJ30383.1 - 0.16 12.2 3.2 0.37 11.0 3.2 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF773 PF05600.12 OAJ30383.1 - 0.23 10.2 0.0 0.23 10.2 0.0 2.5 2 1 0 3 3 3 0 CDK5 regulatory subunit-associated protein 3 GAS PF13851.6 OAJ30383.1 - 1.6 8.1 9.1 0.1 11.9 3.7 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Leu_zip PF15294.6 OAJ30383.1 - 1.9 7.9 7.9 0.35 10.3 3.9 1.8 2 0 0 2 2 2 0 Leucine zipper ABC_tran_CTD PF16326.5 OAJ30383.1 - 3.2 8.1 9.9 66 3.9 6.1 3.3 2 1 0 2 2 2 0 ABC transporter C-terminal domain Gp-FAR-1 PF05823.12 OAJ30383.1 - 4.1 7.7 6.2 0.37 11.1 0.3 2.2 3 0 0 3 3 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Seryl_tRNA_N PF02403.22 OAJ30383.1 - 8.2 6.7 12.7 16 5.7 6.5 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 OAJ30383.1 - 9.8 6.2 9.1 15 5.6 6.1 2.3 2 1 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Sad1_UNC PF07738.13 OAJ30385.1 - 4.8e-08 33.1 0.1 0.017 15.1 0.2 2.9 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Moricin PF06451.11 OAJ30385.1 - 0.025 14.3 0.2 0.062 13.1 0.2 1.6 1 0 0 1 1 1 0 Moricin An_peroxidase PF03098.15 OAJ30386.1 - 3.5e-38 131.5 0.8 2.4e-20 72.6 0.0 4.0 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 OAJ30386.1 - 1.3e-12 47.2 0.0 2.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2235 PF09994.9 OAJ30387.1 - 8e-85 284.7 0.0 1.7e-84 283.6 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 OAJ30387.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ribosomal_L30_N PF08079.12 OAJ30387.1 - 2.2 8.6 7.6 0.091 13.0 1.7 1.6 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain PX PF00787.24 OAJ30388.1 - 1.5e-16 60.4 0.1 8.1e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 OAJ30388.1 - 2.5e-07 30.4 0.4 5.9e-07 29.2 0.4 1.6 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 OAJ30388.1 - 1.8e-05 24.2 0.0 4.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Dimer_Tnp_hAT PF05699.14 OAJ30389.1 - 2.5e-23 81.7 0.2 7.1e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ30389.1 - 0.0087 15.9 0.0 0.028 14.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) zf-BED PF02892.15 OAJ30389.1 - 0.019 15.0 2.0 0.056 13.5 2.0 1.8 1 0 0 1 1 1 0 BED zinc finger SF3b10 PF07189.11 OAJ30391.1 - 2.5e-32 110.8 0.0 2.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MULE PF10551.9 OAJ30392.1 - 5.3e-05 23.6 0.0 0.00018 21.8 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OAJ30392.1 - 0.0028 17.3 0.1 0.0079 15.8 0.1 1.8 1 0 0 1 1 1 1 SWIM zinc finger Peptidase_S9 PF00326.21 OAJ30393.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cullin PF00888.22 OAJ30394.1 - 1.2e-175 585.7 1.8 1.7e-175 585.2 1.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ30394.1 - 4.6e-27 93.8 1.6 1e-26 92.7 1.6 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 OAJ30394.1 - 0.015 15.6 2.9 15 6.0 0.1 4.0 4 0 0 4 4 4 0 Penicillinase repressor HTH_20 PF12840.7 OAJ30394.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4404 PF14357.6 OAJ30394.1 - 0.33 11.6 3.0 11 6.7 0.1 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) Ubie_methyltran PF01209.18 OAJ30395.1 - 1e-70 237.7 0.0 1.6e-37 129.0 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 OAJ30395.1 - 1.2e-12 48.3 0.0 6.2e-11 42.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ30395.1 - 4.1e-12 46.6 0.0 7e-10 39.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ30395.1 - 2e-10 41.3 0.0 4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ30395.1 - 2.7e-07 30.5 0.0 2.6e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ30395.1 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 OAJ30395.1 - 0.0097 15.8 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 1 Hypothetical methyltransferase Glyco_transf_90 PF05686.12 OAJ30395.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 DUF952 PF06108.12 OAJ30396.1 - 8.6e-11 41.7 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) DUF1264 PF06884.11 OAJ30396.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1264) GPI-anchored PF10342.9 OAJ30397.1 - 1.4e-10 41.8 1.4 1.5e-10 41.7 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF11 PF01345.18 OAJ30397.1 - 0.39 11.0 6.2 3 8.2 4.9 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF11 Mob1_phocein PF03637.17 OAJ30398.1 - 2.1e-58 197.1 0.8 2.8e-58 196.7 0.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_4 PF00953.21 OAJ30399.1 - 1e-32 113.3 6.7 2e-32 112.3 6.7 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 4 CAP59_mtransfer PF11735.8 OAJ30401.1 - 2.4e-69 233.7 0.0 4.3e-69 232.9 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Dicty_REP PF05086.12 OAJ30401.1 - 2.6 5.9 5.6 3.5 5.5 5.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spem1 PF15670.5 OAJ30401.1 - 9 5.8 8.0 16 5.0 8.0 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 Fasciclin PF02469.22 OAJ30402.1 - 7e-28 97.4 8.1 8.1e-21 74.6 2.9 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF4993 PF16384.5 OAJ30402.1 - 0.012 14.6 0.7 0.077 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DIL PF01843.19 OAJ30402.1 - 0.16 12.2 0.6 0.44 10.8 0.6 1.7 1 0 0 1 1 1 0 DIL domain DnaJ PF00226.31 OAJ30403.1 - 1.3e-07 31.6 0.0 3.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Peptidase_M3 PF01432.20 OAJ30404.1 - 7.7e-129 430.9 0.0 1e-128 430.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 OAJ30404.1 - 0.08 13.3 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Effector protein Ras PF00071.22 OAJ30405.1 - 2.6e-54 183.2 0.0 3e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ30405.1 - 2.1e-21 76.4 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ30405.1 - 1.5e-07 31.1 0.0 2.8e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 OAJ30405.1 - 0.069 12.9 0.0 3.3 7.5 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 OAJ30405.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 OAJ30405.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 OAJ30405.1 - 0.17 11.8 0.0 20 5.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Dimer_Tnp_hAT PF05699.14 OAJ30406.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Iso_dh PF00180.20 OAJ30408.1 - 2.6e-71 240.6 0.0 3.2e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SR-25 PF10500.9 OAJ30408.1 - 9.3 5.8 6.9 18 4.9 6.9 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glycos_transf_2 PF00535.26 OAJ30410.1 - 9.9e-22 77.5 0.0 7.6e-21 74.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAJ30410.1 - 8.6e-07 29.1 0.0 0.00076 19.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 STG PF15809.5 OAJ30411.1 - 0.019 15.0 1.5 0.025 14.7 1.5 1.2 1 0 0 1 1 1 0 Simian taste bud-specific gene product family SHR3_chaperone PF08229.11 OAJ30413.1 - 2e-36 124.7 0.0 3.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 Med21 PF11221.8 OAJ30413.1 - 1.2 9.4 3.9 1.9 8.7 3.9 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Mss4 PF04421.13 OAJ30414.1 - 3.4e-10 39.9 5.0 7.4e-05 22.8 0.0 2.8 3 0 0 3 3 3 2 Mss4 protein Acetyltransf_1 PF00583.25 OAJ30414.1 - 0.00043 20.5 0.0 0.0016 18.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ30414.1 - 0.2 12.1 0.1 1.1 9.8 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Spt20 PF12090.8 OAJ30414.1 - 3.1 7.3 7.2 0.45 10.1 1.7 2.4 2 0 0 2 2 2 0 Spt20 family DNA_pol_B_palm PF14792.6 OAJ30415.1 - 5.3e-20 71.7 0.1 3.5e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 OAJ30415.1 - 2.4e-19 69.3 0.0 7.8e-19 67.6 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 OAJ30415.1 - 1.9e-08 34.0 0.1 1.2e-07 31.4 0.0 2.4 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 OAJ30415.1 - 4.2e-06 27.0 0.1 9e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 OAJ30415.1 - 4e-05 23.9 0.0 0.0046 17.3 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 OAJ30415.1 - 0.00048 20.7 0.0 0.058 14.0 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain LIG3_BRCT PF16759.5 OAJ30415.1 - 0.33 11.3 1.3 11 6.4 0.0 3.0 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain XPG_N PF00752.17 OAJ30416.1 - 4e-25 88.2 0.0 9.6e-25 87.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ30416.1 - 2.1e-24 85.7 0.0 4.8e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 OAJ30416.1 - 0.00081 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 OAJ30416.1 - 0.058 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TPR_14 PF13428.6 OAJ30416.1 - 0.19 12.6 1.5 0.66 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Hemerythrin PF01814.23 OAJ30417.1 - 4.8e-07 30.5 7.9 4.8e-07 30.5 7.9 1.7 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF2031 PF09592.10 OAJ30417.1 - 0.52 9.8 3.5 0.19 11.2 0.7 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2031) Ndc80_HEC PF03801.13 OAJ30418.1 - 1.1e-34 119.3 0.0 1.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 OAJ30418.1 - 4.8e-09 36.2 0.2 1e-08 35.1 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5595) Exo_endo_phos PF03372.23 OAJ30419.1 - 3.1e-12 46.5 0.1 6e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LSM PF01423.22 OAJ30421.1 - 2e-18 65.8 0.8 2.5e-18 65.5 0.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ30421.1 - 0.028 14.6 0.2 0.034 14.3 0.2 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 OAJ30421.1 - 0.09 12.7 0.9 0.15 12.0 0.9 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF4826 PF16108.5 OAJ30421.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) SRP9-21 PF05486.12 OAJ30422.1 - 2e-10 40.9 1.0 3.3e-08 33.8 1.0 2.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Med3 PF11593.8 OAJ30422.1 - 0.47 9.6 3.0 0.47 9.6 3.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CN_hydrolase PF00795.22 OAJ30423.1 - 2.7e-53 181.0 0.0 3.2e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RRM_1 PF00076.22 OAJ30424.1 - 7.4e-30 102.6 0.1 9.5e-18 63.8 0.2 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 OAJ30424.1 - 6.4e-13 48.7 1.3 7e-05 22.9 0.1 3.1 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain YfdX PF10938.8 OAJ30424.1 - 0.0083 16.1 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 YfdX protein Nup35_RRM PF05172.13 OAJ30424.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MtrG PF04210.13 OAJ30425.1 - 0.071 13.0 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G UBX PF00789.20 OAJ30426.1 - 1.7e-11 44.1 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 UBX domain UDG PF03167.19 OAJ30427.1 - 2.1e-16 60.3 0.0 8.9e-09 35.5 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily FAM199X PF15814.5 OAJ30427.1 - 4.8 6.2 13.2 0.031 13.4 5.0 1.4 2 0 0 2 2 2 0 Protein family FAM199X Xan_ur_permease PF00860.20 OAJ30428.1 - 3.3e-26 91.9 28.5 1.1e-24 86.9 28.5 2.2 1 1 0 1 1 1 1 Permease family Zn_clus PF00172.18 OAJ30429.1 - 2.4e-06 27.5 6.8 4.5e-06 26.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 OAJ30429.1 - 0.14 12.3 0.9 0.26 11.4 0.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) ATPase_2 PF01637.18 OAJ30430.1 - 6.2e-07 29.6 0.1 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 OAJ30430.1 - 0.00026 21.4 1.9 0.0026 18.2 0.3 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 OAJ30430.1 - 0.015 15.6 0.0 0.055 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ30430.1 - 0.32 10.8 1.6 0.82 9.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain RasGAP PF00616.19 OAJ30431.1 - 1.8e-47 161.8 2.3 1.7e-46 158.5 0.0 3.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ30431.1 - 1.3e-46 158.2 4.3 5.6e-46 156.1 4.3 2.3 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 OAJ30431.1 - 6e-23 78.4 28.0 0.024 14.4 0.0 10.0 9 0 0 9 9 9 8 IQ calmodulin-binding motif CH PF00307.31 OAJ30431.1 - 3.8e-16 59.2 0.0 8.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain adh_short PF00106.25 OAJ30432.1 - 4.6e-20 71.9 0.0 8.7e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ30432.1 - 1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF282 PF03380.14 OAJ30432.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 KR PF08659.10 OAJ30432.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain PK PF00224.21 OAJ30433.1 - 6.3e-160 531.8 1.1 7.7e-160 531.5 1.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 OAJ30433.1 - 2.8e-37 127.5 0.0 6.7e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 OAJ30433.1 - 0.00028 20.1 0.9 0.001 18.3 0.9 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 OAJ30433.1 - 0.0045 16.0 0.3 0.051 12.6 0.0 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Cellulase PF00150.18 OAJ30433.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) HVSL PF09749.9 OAJ30435.1 - 2.2e-33 115.7 0.0 2.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein tRNA-synt_1 PF00133.22 OAJ30436.1 - 3.2e-42 144.6 0.0 2.7e-33 115.1 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 OAJ30436.1 - 3.1e-13 49.3 0.0 1.1e-07 31.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 OAJ30436.1 - 1.1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 OAJ30436.1 - 2.3e-07 30.5 0.0 4.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 OAJ30436.1 - 0.0079 15.7 0.2 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 adh_short_C2 PF13561.6 OAJ30437.1 - 1.1e-37 129.9 0.1 1.4e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ30437.1 - 8.7e-30 103.6 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ30437.1 - 1.2e-06 28.6 0.2 1.7e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 OAJ30437.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 OAJ30437.1 - 0.04 13.2 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 OAJ30437.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NYN PF01936.18 OAJ30438.1 - 1e-22 81.2 0.0 2.4e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 NYN domain DNA_pol_phi PF04931.13 OAJ30438.1 - 0.58 8.2 6.8 0.92 7.5 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RabGAP-TBC PF00566.18 OAJ30439.1 - 1.2e-30 106.8 5.7 1.8e-29 103.0 0.0 3.4 4 0 0 4 4 4 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 OAJ30439.1 - 0.0034 16.9 0.0 0.062 12.8 0.0 2.8 3 1 0 3 3 3 1 Rab-binding domain (RBD) PIG-P PF08510.12 OAJ30440.1 - 1.7e-25 89.2 3.6 2.9e-25 88.5 3.6 1.4 1 1 0 1 1 1 1 PIG-P DUF936 PF06075.12 OAJ30441.1 - 0.02 13.9 0.6 0.021 13.7 0.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF1348 PF07080.11 OAJ30442.1 - 4.5e-60 201.3 5.6 5.1e-60 201.1 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 OAJ30442.1 - 3.1e-07 31.0 0.0 4.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 OAJ30442.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Oxysterol_BP PF01237.18 OAJ30443.1 - 7.6e-68 229.0 0.0 2.2e-65 220.9 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein WSD PF15613.6 OAJ30443.1 - 0.11 13.0 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif LMWPc PF01451.21 OAJ30444.1 - 6.1e-36 123.9 0.0 7e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TSGP1 PF07771.11 OAJ30445.1 - 0.0024 18.0 11.9 0.37 10.9 0.2 4.2 3 1 1 4 4 4 3 Tick salivary peptide group 1 Prenyltransf PF01255.19 OAJ30446.1 - 3.2e-72 242.7 0.0 4.2e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Rer1 PF03248.13 OAJ30446.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.3 1 0 0 1 1 1 0 Rer1 family Sgf11 PF08209.11 OAJ30449.1 - 1e-13 50.6 3.9 4.2e-13 48.6 0.7 2.3 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 OAJ30449.1 - 0.19 11.6 1.4 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Peptidase_M13_N PF05649.13 OAJ30451.1 - 5.6e-06 26.3 0.0 6.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 ArgoMid PF16487.5 OAJ30452.1 - 0.005 17.1 0.0 0.0085 16.3 0.0 1.4 1 0 0 1 1 1 1 Mid domain of argonaute Ank_4 PF13637.6 OAJ30453.1 - 1e-11 45.1 0.0 2.8e-06 27.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ30453.1 - 4.4e-11 43.2 0.0 4.2e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ30453.1 - 4.9e-07 29.9 0.1 0.1 12.9 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ30453.1 - 6.7e-07 29.1 0.0 0.049 14.2 0.0 4.3 4 1 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ30453.1 - 0.00071 19.9 0.0 3.2 8.3 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat NOA36 PF06524.12 OAJ30453.1 - 0.22 10.8 16.7 0.29 10.4 16.7 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 OAJ30453.1 - 0.32 11.0 7.5 0.47 10.5 7.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 OAJ30453.1 - 0.38 10.1 11.8 0.54 9.6 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cwf_Cwc_15 PF04889.12 OAJ30453.1 - 0.51 10.0 11.7 0.65 9.7 11.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 OAJ30453.1 - 0.58 9.7 8.4 0.68 9.5 8.4 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 OAJ30453.1 - 1 8.7 10.9 1.2 8.5 10.9 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 OAJ30453.1 - 1.2 7.3 11.9 1.6 7.0 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ30453.1 - 1.3 7.1 13.2 1.5 6.9 13.2 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ30453.1 - 1.3 7.0 17.8 1.7 6.6 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 OAJ30453.1 - 2.8 7.0 19.6 3.3 6.8 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 OAJ30453.1 - 4.1 7.2 10.7 5.4 6.8 10.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 OAJ30453.1 - 7.2 6.3 7.5 12 5.5 7.5 1.4 1 0 0 1 1 1 0 FAM176 family NMT_C PF02799.15 OAJ30454.1 - 1.4e-72 243.6 0.0 3.4e-72 242.3 0.0 1.6 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 OAJ30454.1 - 8.9e-72 240.1 0.0 1.4e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 OAJ30454.1 - 0.006 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 OAJ30454.1 - 0.029 14.6 0.0 0.079 13.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ30454.1 - 0.18 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HC2 PF07382.11 OAJ30455.1 - 3.6e-13 50.0 47.9 3.6e-13 50.0 47.9 7.1 2 2 5 7 7 7 2 Histone H1-like nucleoprotein HC2 PAZ PF02170.22 OAJ30456.1 - 0.0025 17.6 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 PAZ domain DUF1797 PF08796.10 OAJ30456.1 - 0.041 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) API5 PF05918.11 OAJ30456.1 - 8.4 5.1 5.3 10 4.8 5.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CTNNBL PF08216.11 OAJ30457.1 - 8e-33 112.7 0.3 2.7e-32 111.0 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.6 OAJ30457.1 - 0.026 14.9 1.2 0.95 9.9 0.1 3.6 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.23 OAJ30457.1 - 0.085 12.9 1.9 2 8.6 0.1 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 OAJ30457.1 - 0.1 12.9 0.6 4.7 7.7 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat Pox_E10 PF04805.12 OAJ30457.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 E10-like protein conserved region AT_hook PF02178.19 OAJ30458.1 - 0.0073 16.0 21.0 0.072 13.0 4.6 3.1 2 0 0 2 2 2 2 AT hook motif MFS_1 PF07690.16 OAJ30459.1 - 4.3e-28 98.2 28.0 1.6e-27 96.4 27.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.22 OAJ30461.1 - 4.4e-19 68.1 0.0 6.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ30461.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Rpr2 PF04032.16 OAJ30462.1 - 0.0046 17.2 0.1 0.048 13.9 0.1 2.5 1 1 1 2 2 2 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain WD40 PF00400.32 OAJ30463.1 - 2.9e-07 31.1 9.0 0.00074 20.3 0.4 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ30463.1 - 0.0002 21.6 0.0 0.13 12.6 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain tRNA_Me_trans PF03054.16 OAJ30464.1 - 3.7e-93 312.1 0.0 8e-81 271.6 0.0 2.9 2 1 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 OAJ30464.1 - 1.4e-05 24.3 0.0 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.14 OAJ30464.1 - 0.0046 16.6 0.0 0.0078 15.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Mitoc_mL59 PF18126.1 OAJ30465.1 - 2.3e-27 95.8 14.5 5.4e-27 94.6 14.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Kelch_4 PF13418.6 OAJ30467.1 - 1.8e-34 117.5 11.8 1.4e-05 25.0 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ30467.1 - 5.4e-29 99.5 5.0 9.5e-06 25.1 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 OAJ30467.1 - 9.3e-28 95.7 7.0 2.9e-06 27.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 OAJ30467.1 - 1.4e-25 89.0 10.8 1.7e-06 28.2 0.3 7.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ30467.1 - 5.5e-23 80.4 5.6 0.00021 21.5 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.15 OAJ30467.1 - 5.4e-22 76.9 9.2 5.4e-05 23.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Adaptin_N PF01602.20 OAJ30468.1 - 4.3e-55 187.3 0.0 9.9e-33 113.5 0.0 3.2 3 0 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 OAJ30468.1 - 5.4e-10 39.5 0.0 2.4e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ30468.1 - 1.7e-05 24.7 4.4 1.5 9.3 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OAJ30468.1 - 3.9e-05 24.0 3.5 3.9e-05 24.0 3.5 5.6 6 2 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 OAJ30468.1 - 7e-05 23.2 1.4 7e-05 23.2 1.4 5.5 3 1 2 5 5 5 2 HEAT-like repeat Myc_N PF01056.18 OAJ30468.1 - 0.006 16.5 1.5 0.006 16.5 1.5 3.6 3 0 0 3 3 3 1 Myc amino-terminal region Chs7 PF12271.8 OAJ30470.1 - 1.2e-115 385.8 17.8 1.4e-115 385.6 17.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone SOG2 PF10428.9 OAJ30471.1 - 0.14 11.3 24.2 0.2 10.8 24.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Dickkopf_N PF04706.12 OAJ30471.1 - 0.17 12.4 0.2 0.17 12.4 0.2 10.0 6 4 2 9 9 9 0 Dickkopf N-terminal cysteine-rich region Dickkopf_N PF04706.12 OAJ30472.1 - 0.12 12.9 0.4 0.12 12.9 0.4 9.8 7 4 3 10 10 10 0 Dickkopf N-terminal cysteine-rich region Utp14 PF04615.13 OAJ30472.1 - 5 5.6 20.1 6.3 5.2 20.1 1.0 1 0 0 1 1 1 0 Utp14 protein RRM_1 PF00076.22 OAJ30473.1 - 5.2e-08 32.6 0.0 6.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ30473.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ30473.1 - 0.063 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ30473.1 - 0.094 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Phage_integrase PF00589.22 OAJ30474.1 - 2.1e-05 24.4 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family DUF3504 PF12012.8 OAJ30474.1 - 0.0018 18.2 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) HIT PF01230.23 OAJ30475.1 - 9.2e-09 35.9 0.0 1.5e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ30475.1 - 0.00079 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ30475.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Zn_clus PF00172.18 OAJ30476.1 - 1.6e-07 31.3 9.6 2.9e-07 30.5 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L19e PF01280.20 OAJ30476.1 - 0.81 9.7 4.7 7.6 6.6 1.4 2.6 2 0 0 2 2 2 0 Ribosomal protein L19e Methyltransf_16 PF10294.9 OAJ30477.1 - 1e-39 136.1 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 OAJ30477.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ30477.1 - 0.033 14.9 0.1 0.071 13.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ30477.1 - 0.081 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.21 OAJ30478.1 - 3.5e-06 26.6 0.1 2.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Dioxygenase DNA_pol_phi PF04931.13 OAJ30479.1 - 4.8e-21 74.6 39.6 8.3e-21 73.8 39.6 1.3 1 0 0 1 1 1 1 DNA polymerase phi AAA_lid_7 PF17867.1 OAJ30479.1 - 0.021 15.0 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Midasin AAA lid domain FancD2 PF14631.6 OAJ30480.1 - 8 3.7 8.0 19 2.5 8.0 1.5 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Autophagy_act_C PF03987.15 OAJ30481.1 - 4.4e-16 59.2 1.1 7.9e-16 58.4 0.2 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain DUF515 PF04415.12 OAJ30481.1 - 5 5.4 10.3 7 4.9 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RabGAP-TBC PF00566.18 OAJ30482.1 - 5.7e-49 166.7 0.0 7.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 OAJ30482.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ30482.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain RRM_1 PF00076.22 OAJ30483.1 - 1.5e-12 47.1 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 OAJ30483.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 OAJ30483.1 - 0.079 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Ctr PF04145.15 OAJ30485.1 - 6.6 7.3 7.5 54 4.4 2.9 3.7 2 2 0 2 2 2 0 Ctr copper transporter family SET PF00856.28 OAJ30486.1 - 7e-19 68.8 0.3 7e-19 68.8 0.3 3.1 2 2 0 2 2 2 1 SET domain SRI PF08236.11 OAJ30486.1 - 2.6e-17 62.8 7.8 2.6e-17 62.8 7.8 2.0 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 OAJ30486.1 - 7.3e-13 48.3 4.0 7.3e-13 48.3 4.0 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 OAJ30486.1 - 0.029 14.4 1.2 0.055 13.5 0.1 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain SOAR PF16533.5 OAJ30486.1 - 0.041 13.8 0.6 0.041 13.8 0.6 2.9 3 0 0 3 3 3 0 STIM1 Orai1-activating region Macoilin PF09726.9 OAJ30486.1 - 2.5 6.6 13.5 4.8 5.6 13.5 1.4 1 0 0 1 1 1 0 Macoilin family Abhydrolase_6 PF12697.7 OAJ30487.1 - 0.00069 20.3 0.0 0.001 19.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Metallophos PF00149.28 OAJ30487.1 - 0.039 14.5 0.1 0.37 11.2 0.0 2.3 2 1 0 2 2 2 0 Calcineurin-like phosphoesterase Amino_oxidase PF01593.24 OAJ30488.1 - 1.3e-55 189.5 0.2 1.7e-55 189.2 0.2 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ30488.1 - 3e-11 43.4 1.0 7.5e-11 42.1 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 OAJ30488.1 - 1.4e-06 27.3 1.0 0.00077 18.3 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 OAJ30488.1 - 7.4e-06 25.8 2.8 3.7e-05 23.5 2.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ30488.1 - 9.7e-06 24.9 1.2 1.6e-05 24.2 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 OAJ30488.1 - 3.1e-05 24.4 0.2 0.0011 19.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ30488.1 - 0.00017 20.9 0.8 0.0012 18.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ30488.1 - 0.00043 19.6 0.1 0.00077 18.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAJ30488.1 - 0.00099 18.4 1.9 0.0015 17.8 0.8 1.9 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 OAJ30488.1 - 0.0011 18.5 1.3 0.0016 17.8 1.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ30488.1 - 0.0013 18.1 2.5 0.031 13.5 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ30488.1 - 0.0026 17.8 0.5 0.68 9.9 0.2 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 OAJ30488.1 - 0.003 16.7 0.1 1.9 7.5 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAJ30488.1 - 0.015 14.6 0.5 0.028 13.7 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAJ30488.1 - 0.076 12.1 1.4 0.28 10.2 0.7 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_cc PF11790.8 OAJ30489.1 - 4.4e-54 183.6 1.9 5.6e-54 183.2 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RVT_2 PF07727.14 OAJ30491.1 - 4.7e-73 245.8 0.0 6.8e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ30491.1 - 3e-12 46.8 0.0 1.6e-11 44.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ30491.1 - 5.5e-06 26.1 0.0 2e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Crr6 PF08847.11 OAJ30491.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Diphthamide_syn PF01866.17 OAJ30492.1 - 3.8e-84 282.7 0.0 9.8e-47 159.8 0.0 3.2 2 1 0 2 2 2 2 Putative diphthamide synthesis protein Arrestin_N PF00339.29 OAJ30493.1 - 0.00047 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 OAJ30493.1 - 0.0036 16.5 0.0 0.0069 15.6 0.0 1.3 1 0 0 1 1 1 1 Rgp1 HMG_box PF00505.19 OAJ30495.1 - 3.2e-08 33.9 1.3 0.00019 21.8 0.4 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box 6PF2K PF01591.18 OAJ30496.1 - 2.2e-63 213.5 0.0 3.1e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ30496.1 - 8e-22 77.9 0.3 1.5e-19 70.5 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ30496.1 - 0.00019 21.6 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ30496.1 - 0.0052 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pkinase PF00069.25 OAJ30498.1 - 9.1e-08 31.8 0.0 6.3e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30498.1 - 1.3e-05 24.6 0.0 0.11 11.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Trimer_CC PF08954.11 OAJ30499.1 - 0.02 14.4 0.1 0.038 13.5 0.1 1.4 1 0 0 1 1 1 0 Trimerisation motif Pkinase PF00069.25 OAJ30500.1 - 6.8e-05 22.4 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30500.1 - 0.0037 16.6 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_M43 PF05572.13 OAJ30502.1 - 2.1e-08 34.2 0.1 5e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ30502.1 - 0.081 13.4 1.4 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like CRAL_TRIO PF00650.20 OAJ30503.1 - 2e-11 43.9 0.0 1e-10 41.5 0.0 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain Bunya_NS-S PF01104.17 OAJ30503.1 - 0.2 11.5 0.9 0.43 10.4 0.9 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s Cellulase PF00150.18 OAJ30504.1 - 9.5e-12 44.9 5.9 1.4e-11 44.4 5.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Redoxin PF08534.10 OAJ30505.1 - 2.4e-32 111.7 0.0 2.7e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ30505.1 - 1.5e-07 31.4 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Oxidored_FMN PF00724.20 OAJ30506.1 - 3.1e-60 204.2 0.0 3.9e-56 190.8 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Nuc_deoxyrib_tr PF05014.15 OAJ30506.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF4681 PF15732.5 OAJ30508.1 - 0.15 12.3 0.3 0.19 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) HTH_Tnp_Tc5 PF03221.16 OAJ30511.1 - 0.00017 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain FUN14 PF04930.15 OAJ30512.1 - 4.5e-20 71.9 1.9 8.1e-20 71.0 1.9 1.4 1 0 0 1 1 1 1 FUN14 family p450 PF00067.22 OAJ30513.1 - 3.2e-72 243.8 0.0 4.2e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.23 OAJ30514.1 - 5.3e-19 67.7 0.0 4.9e-10 39.0 0.2 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAJ30514.1 - 1.1e-09 38.0 0.4 3.3e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ30515.1 - 5.3e-21 74.2 0.0 6.5e-08 32.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ30515.1 - 3.3e-08 33.2 0.0 0.0004 20.1 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like NAD_binding_9 PF13454.6 OAJ30516.1 - 0.021 14.8 0.8 0.032 14.2 0.8 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Med9 PF07544.13 OAJ30516.1 - 0.036 14.2 0.8 5.3 7.2 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AKNA PF12443.8 OAJ30516.1 - 0.071 13.8 0.3 0.12 13.0 0.3 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor Tox-ODYAM1 PF15642.6 OAJ30516.1 - 0.37 9.7 2.3 0.46 9.4 2.3 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc7 PF08317.11 OAJ30516.1 - 0.42 9.4 4.0 0.48 9.3 4.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RCDG1 PF15725.5 OAJ30517.1 - 0.031 14.7 0.8 0.043 14.2 0.8 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein BAR_3_WASP_bdg PF10456.9 OAJ30517.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein SF3b1 PF08920.10 OAJ30518.1 - 3.9e-27 95.1 3.5 1.2e-26 93.5 2.3 2.9 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 OAJ30518.1 - 4.8e-14 52.5 7.0 0.0094 16.4 0.0 8.2 7 2 1 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.6 OAJ30518.1 - 2.4e-10 40.7 11.3 0.00092 19.6 0.2 8.3 4 2 4 8 8 8 2 HEAT repeats Adaptin_N PF01602.20 OAJ30518.1 - 9e-08 31.1 0.6 0.00062 18.4 0.0 3.0 1 1 1 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 OAJ30518.1 - 1.1e-07 31.9 1.4 0.0042 17.0 0.1 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) NUC173 PF08161.12 OAJ30518.1 - 2.9e-06 27.1 1.1 0.4 10.3 0.0 4.9 3 2 2 6 6 6 2 NUC173 domain HEAT PF02985.22 OAJ30518.1 - 7.3e-06 25.8 11.2 2.8 8.4 0.1 9.0 10 0 0 10 10 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ30518.1 - 1.2e-05 25.8 0.5 1.7 9.3 0.0 5.4 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ30518.1 - 3.9e-05 23.8 1.7 18 5.4 0.0 5.8 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 OAJ30518.1 - 7.6e-05 22.4 0.6 0.29 10.7 0.0 3.7 4 0 0 4 4 4 1 CLASP N terminal MMS19_C PF12460.8 OAJ30518.1 - 0.00093 18.4 0.0 2 7.4 0.0 3.8 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 OAJ30518.1 - 0.0011 18.2 1.0 0.026 13.6 0.0 3.0 3 0 0 3 3 3 1 Dopey, N-terminal UME PF08064.13 OAJ30518.1 - 0.012 15.6 0.0 4.1 7.4 0.0 4.5 4 1 1 5 5 5 0 UME (NUC010) domain LIDHydrolase PF10230.9 OAJ30518.1 - 0.012 15.2 0.2 0.041 13.4 0.1 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DNA_pol_phi PF04931.13 OAJ30518.1 - 0.12 10.5 0.2 7.1 4.6 0.1 2.3 1 1 1 2 2 2 0 DNA polymerase phi TPR_12 PF13424.6 OAJ30519.1 - 1.3e-09 38.2 16.2 0.016 15.5 1.8 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ30519.1 - 1.1e-07 31.4 8.5 0.86 9.9 0.5 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 OAJ30519.1 - 0.0008 18.9 5.7 0.011 15.1 0.0 3.7 3 1 1 4 4 4 1 MalT-like TPR region TPR_1 PF00515.28 OAJ30519.1 - 0.0012 18.6 1.9 6.3 6.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 OAJ30519.1 - 0.0013 18.8 0.3 0.016 15.3 0.2 2.7 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 OAJ30519.1 - 0.0025 18.5 23.3 2.2 9.3 0.0 8.9 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ30519.1 - 0.004 17.1 3.3 1.9 8.7 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ30519.1 - 0.0074 16.9 15.4 3.3 8.4 2.3 6.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ30519.1 - 0.02 14.8 11.7 21 5.2 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ30519.1 - 0.07 13.7 13.1 1.1 9.8 1.7 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ30519.1 - 0.13 13.0 10.8 0.7 10.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SMBP PF16785.5 OAJ30519.1 - 0.43 10.8 1.8 4.5 7.5 0.0 3.4 4 0 0 4 4 4 0 Small metal-binding protein ubiquitin PF00240.23 OAJ30520.1 - 6.1e-10 38.7 0.1 0.00013 21.6 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAJ30520.1 - 0.00074 19.3 0.0 0.0082 15.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RBD PF02196.15 OAJ30520.1 - 0.004 17.2 0.0 0.068 13.3 0.0 2.3 2 0 0 2 2 2 1 Raf-like Ras-binding domain GP40 PF11025.8 OAJ30520.1 - 0.0083 15.9 0.0 0.0088 15.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotein GP40 of Cryptosporidium UN_NPL4 PF11543.8 OAJ30520.1 - 0.0097 16.4 0.0 0.6 10.6 0.0 2.6 2 1 1 3 3 3 1 Nuclear pore localisation protein NPL4 Cobl PF09469.10 OAJ30520.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain TUG-UBL1 PF11470.8 OAJ30520.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain ubiquitin PF00240.23 OAJ30521.1 - 1.6e-30 104.6 0.2 1.4e-11 43.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ30521.1 - 5.9e-13 48.5 0.4 4.4e-06 26.4 0.1 3.2 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ30521.1 - 0.004 17.6 0.2 12 6.4 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin-like domain DDE_Tnp_1_6 PF13751.6 OAJ30521.1 - 0.018 15.3 0.1 6.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF4634 PF15465.6 OAJ30521.1 - 0.099 13.0 0.3 0.83 10.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) Mpp10 PF04006.12 OAJ30522.1 - 0.059 11.8 3.1 0.069 11.6 3.1 1.1 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.11 OAJ30522.1 - 0.089 12.4 4.4 0.2 11.2 4.4 1.6 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 OAJ30522.1 - 0.19 11.2 5.4 0.25 10.7 5.4 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 OAJ30522.1 - 0.2 11.5 1.3 0.3 11.0 1.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.12 OAJ30522.1 - 0.31 10.4 5.9 0.5 9.7 5.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 OAJ30522.1 - 0.5 10.8 15.1 1.3 9.5 15.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 OAJ30522.1 - 0.94 7.7 4.0 1.2 7.3 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 OAJ30522.1 - 1 7.5 7.1 1.3 7.1 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 OAJ30522.1 - 2.7 6.0 8.9 3.5 5.6 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.11 OAJ30522.1 - 2.7 6.7 4.0 4 6.1 4.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 OAJ30522.1 - 9 5.5 11.7 14 4.9 11.7 1.2 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 OAJ30522.1 - 10 7.2 14.2 31 5.6 14.2 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Vps52 PF04129.12 OAJ30523.1 - 6.4e-39 134.1 0.0 2.7e-36 125.4 0.0 2.3 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 OAJ30523.1 - 7.4e-05 21.4 0.0 0.00015 20.3 0.0 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec3 PBP1_TM PF14812.6 OAJ30523.1 - 0.13 12.6 7.2 0.26 11.7 7.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 OAJ30523.1 - 0.19 11.4 14.8 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ30523.1 - 0.65 9.3 11.7 0.96 8.7 11.7 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 OAJ30523.1 - 1.4 8.6 4.0 2.8 7.6 4.0 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 OAJ30523.1 - 4.6 5.2 13.0 7 4.6 13.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 OAJ30523.1 - 4.7 5.4 7.9 7.9 4.6 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 OAJ30523.1 - 6 6.7 6.9 1.5 8.7 3.4 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.12 OAJ30523.1 - 9.7 4.3 10.4 1.9 6.6 6.7 1.6 2 0 0 2 2 2 0 Nop14-like family NPR2 PF06218.11 OAJ30524.1 - 1.6e-98 330.3 0.3 5.3e-43 147.4 0.3 5.1 3 2 1 4 4 4 4 Nitrogen permease regulator 2 NPR3 PF03666.13 OAJ30524.1 - 0.00091 18.1 1.1 0.09 11.6 0.3 2.2 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 Menin PF05053.13 OAJ30524.1 - 1 7.6 2.2 2.2 6.6 2.2 1.4 1 0 0 1 1 1 0 Menin ATP_bind_1 PF03029.17 OAJ30525.1 - 1e-83 280.8 0.0 1.4e-81 273.8 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 OAJ30525.1 - 4.5e-05 23.3 0.0 0.0073 16.1 0.0 2.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 OAJ30525.1 - 5.6e-05 23.2 0.0 8.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 OAJ30525.1 - 0.0011 19.3 0.4 0.028 14.7 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 OAJ30525.1 - 0.0012 18.5 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 OAJ30525.1 - 0.0033 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.6 OAJ30525.1 - 0.0036 17.2 0.0 0.55 10.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 OAJ30525.1 - 0.0043 17.2 1.3 0.0091 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ30525.1 - 0.007 16.9 0.0 0.021 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 OAJ30525.1 - 0.0093 15.3 0.0 0.042 13.2 0.0 1.9 1 1 0 1 1 1 1 KaiC FtsK_SpoIIIE PF01580.18 OAJ30525.1 - 0.0097 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 OAJ30525.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 OAJ30525.1 - 0.028 13.9 0.1 0.71 9.4 0.0 2.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 OAJ30525.1 - 0.03 14.7 0.1 0.098 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OAJ30525.1 - 0.032 13.3 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 OAJ30525.1 - 0.036 13.8 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADSL_C PF10397.9 OAJ30525.1 - 0.048 14.2 0.2 0.1 13.2 0.2 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus RNA_helicase PF00910.22 OAJ30525.1 - 0.07 13.5 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 OAJ30525.1 - 0.083 13.2 0.1 3.9 7.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 OAJ30525.1 - 0.089 11.8 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 OAJ30525.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase DUF87 PF01935.17 OAJ30525.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 OAJ30525.1 - 0.13 12.7 0.1 1.6 9.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 OAJ30525.1 - 0.14 11.5 0.0 0.61 9.5 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.15 OAJ30525.1 - 0.17 11.8 0.0 1.6 8.6 0.0 2.3 1 1 0 1 1 1 0 NTPase CAF1A PF12253.8 OAJ30526.1 - 6.3e-23 80.7 6.9 6.3e-23 80.7 6.9 4.3 2 2 2 4 4 4 1 Chromatin assembly factor 1 subunit A Mitofilin PF09731.9 OAJ30526.1 - 0.008 15.1 35.5 0.016 14.1 35.5 1.4 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 OAJ30526.1 - 0.031 12.8 34.7 0.057 11.9 34.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HGTP_anticodon2 PF12745.7 OAJ30526.1 - 0.2 11.1 24.2 0.5 9.8 24.2 1.6 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs BAF1_ABF1 PF04684.13 OAJ30526.1 - 5.3 6.0 32.4 12 4.8 27.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor GAS2 PF02187.17 OAJ30527.1 - 7.3e-12 45.2 0.0 2.4e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HAMP PF00672.25 OAJ30527.1 - 1.2 9.6 3.7 3.9 7.9 0.1 3.7 3 0 0 3 3 3 0 HAMP domain zf-MYND PF01753.18 OAJ30528.1 - 1.2e-09 38.0 13.7 1.2e-09 38.0 13.7 2.8 2 1 0 2 2 2 1 MYND finger SET PF00856.28 OAJ30528.1 - 1.4e-06 28.8 0.2 5.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 SET domain zinc_ribbon_4 PF13717.6 OAJ30528.1 - 0.49 10.4 4.8 1.8 8.6 1.9 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 OAJ30528.1 - 2.1 8.1 5.0 14 5.4 1.4 3.1 2 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit AA_kinase PF00696.28 OAJ30529.1 - 7.2e-32 110.9 0.2 9e-32 110.6 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family Dynamin_N PF00350.23 OAJ30530.1 - 1.8e-41 142.0 0.0 3.3e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 OAJ30530.1 - 4e-05 23.7 0.0 0.00016 21.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 OAJ30530.1 - 0.0009 18.5 0.0 0.0029 16.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region AAA_15 PF13175.6 OAJ30530.1 - 0.052 13.3 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAJ30530.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_S58 PF03576.14 OAJ30530.1 - 0.075 12.5 2.6 0.25 10.8 2.2 1.9 2 0 0 2 2 2 0 Peptidase family S58 Hfq PF17209.3 OAJ30531.1 - 0.23 11.1 0.0 0.47 10.1 0.0 1.5 1 0 0 1 1 1 0 Hfq protein SRP40_C PF05022.12 OAJ30533.1 - 1e-28 100.0 5.7 4.7e-28 97.9 5.7 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain Spt20 PF12090.8 OAJ30534.1 - 1.4 8.5 5.9 4.2 6.9 5.9 1.8 1 0 0 1 1 1 0 Spt20 family Transposase_21 PF02992.14 OAJ30535.1 - 2.6e-07 30.1 0.0 4.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 OAJ30535.1 - 1.1e-06 28.3 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1258 PF06869.12 OAJ30535.1 - 0.0014 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) PBP1_TM PF14812.6 OAJ30535.1 - 0.0042 17.4 5.1 0.0064 16.8 2.8 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Plavaka PF18759.1 OAJ30535.1 - 0.019 14.2 0.9 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 Plavaka transposase Pns11_12 PF17464.2 OAJ30535.1 - 0.42 10.3 6.8 0.75 9.5 6.8 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 TLP-20 PF06088.11 OAJ30535.1 - 0.92 9.4 3.3 2.2 8.2 3.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RPN2_C PF18004.1 OAJ30535.1 - 6.2 6.7 8.4 11 5.9 8.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain vATP-synt_AC39 PF01992.16 OAJ30538.1 - 3.3e-108 362.2 0.0 3.7e-108 362.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CDC45 PF02724.14 OAJ30540.1 - 0.024 12.9 0.7 0.041 12.2 0.7 1.3 1 0 0 1 1 1 0 CDC45-like protein 3Beta_HSD PF01073.19 OAJ30541.1 - 9.7e-19 67.4 0.0 6e-18 64.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ30541.1 - 3e-16 59.6 0.1 6.2e-16 58.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 OAJ30541.1 - 1.4e-12 47.9 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAJ30541.1 - 4.6e-11 42.4 0.0 1.3e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 OAJ30541.1 - 3.1e-08 33.4 0.0 1.7e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 OAJ30541.1 - 5.1e-08 32.8 0.0 7.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 OAJ30541.1 - 3.4e-05 23.1 0.1 5.3e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 OAJ30541.1 - 0.00014 21.3 0.8 0.014 14.9 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 OAJ30541.1 - 0.0064 16.8 0.0 0.019 15.2 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAJ30541.1 - 0.0093 16.1 0.0 0.038 14.2 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 OAJ30541.1 - 0.048 12.8 0.1 0.089 11.9 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 OAJ30541.1 - 0.078 12.9 0.3 1.8 8.4 0.3 2.2 1 1 0 1 1 1 0 KR domain Ribosomal_S8 PF00410.19 OAJ30542.1 - 7.2e-12 45.4 0.0 7.2e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 DUF3385 PF11865.8 OAJ30543.1 - 9.2e-49 165.4 0.0 1.5e-43 148.5 0.0 4.1 2 1 1 3 3 3 3 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OAJ30543.1 - 8.2e-17 61.4 27.0 0.00096 19.5 0.2 11.5 9 2 2 12 12 12 5 HEAT repeats HEAT PF02985.22 OAJ30543.1 - 7.1e-15 53.8 20.8 0.061 13.6 0.2 11.2 11 0 0 11 11 11 4 HEAT repeat UME PF08064.13 OAJ30543.1 - 1.1e-06 28.5 0.3 0.73 9.8 0.0 6.2 5 1 2 7 7 7 1 UME (NUC010) domain Cnd1 PF12717.7 OAJ30543.1 - 8.7e-06 25.9 2.3 0.65 10.0 0.0 5.0 3 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 OAJ30543.1 - 2.4e-05 23.6 1.6 2.1 7.4 0.0 4.7 5 1 0 5 5 5 2 Interferon-related developmental regulator (IFRD) FAT PF02259.23 OAJ30543.1 - 0.00017 21.0 0.3 0.00017 21.0 0.3 2.1 2 0 0 2 2 2 1 FAT domain HEAT_EZ PF13513.6 OAJ30543.1 - 0.00038 20.9 46.6 0.0093 16.5 0.1 12.8 13 3 4 17 17 13 5 HEAT-like repeat Ecm29 PF13001.7 OAJ30543.1 - 0.00083 18.1 0.9 0.051 12.2 0.0 2.9 3 0 0 3 3 3 1 Proteasome stabiliser Adaptin_N PF01602.20 OAJ30543.1 - 0.0017 17.0 6.4 0.62 8.5 1.0 4.7 4 1 2 6 6 6 2 Adaptin N terminal region GPP34 PF05719.11 OAJ30543.1 - 0.0017 18.4 0.5 0.0079 16.3 0.5 2.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Vac14_Fab1_bd PF12755.7 OAJ30543.1 - 0.006 17.1 0.2 12 6.6 0.0 5.5 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region VHS PF00790.19 OAJ30543.1 - 0.0061 16.4 0.1 13 5.7 0.0 4.0 5 0 0 5 5 5 0 VHS domain DUF3535 PF12054.8 OAJ30543.1 - 0.036 13.3 1.9 1.1 8.4 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3535) Arm PF00514.23 OAJ30543.1 - 0.82 9.8 6.3 42 4.4 0.0 6.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 OAJ30543.1 - 1.1 8.3 3.9 38 3.2 0.1 3.8 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal ACPS PF01648.20 OAJ30544.1 - 4.5e-12 46.1 0.3 2.2e-11 43.9 0.3 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ABC_membrane PF00664.23 OAJ30545.1 - 7.3e-84 281.7 23.2 3.9e-43 148.1 10.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ30545.1 - 1.9e-60 203.3 0.0 1.4e-32 113.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ30545.1 - 1.5e-10 40.9 0.5 0.0036 16.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ30545.1 - 1.2e-07 31.9 1.3 0.0044 16.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 OAJ30545.1 - 4.2e-07 30.5 5.6 8.3e-05 23.0 0.1 3.6 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ30545.1 - 3.6e-06 26.6 2.1 0.062 13.0 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 OAJ30545.1 - 4.6e-05 24.0 0.0 0.23 12.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 OAJ30545.1 - 7.8e-05 22.3 0.3 0.52 9.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 OAJ30545.1 - 0.00017 21.6 0.3 0.072 13.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 OAJ30545.1 - 0.0016 18.2 0.6 3.6 7.3 0.3 3.5 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 OAJ30545.1 - 0.0037 17.3 0.6 2.1 8.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ30545.1 - 0.004 16.9 0.3 5.2 6.8 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAJ30545.1 - 0.0054 17.0 5.9 0.78 10.0 1.2 3.9 3 1 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 OAJ30545.1 - 0.0055 15.6 0.4 1.4 7.6 0.0 2.8 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 OAJ30545.1 - 0.0071 16.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OAJ30545.1 - 0.011 15.1 0.3 1.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 OAJ30545.1 - 0.015 15.0 0.1 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 OAJ30545.1 - 0.015 15.4 2.6 1.5 8.9 0.2 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 OAJ30545.1 - 0.016 15.7 1.0 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ30545.1 - 0.027 14.7 1.1 8.3 6.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 OAJ30545.1 - 0.032 13.4 0.1 0.56 9.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 OAJ30545.1 - 0.034 13.5 0.9 6.4 6.1 0.0 3.3 4 0 0 4 4 3 0 Bacterial TniB protein Sigma54_activat PF00158.26 OAJ30545.1 - 0.037 13.7 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 OAJ30545.1 - 0.054 13.4 0.2 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.22 OAJ30545.1 - 0.063 13.7 0.2 3.9 7.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 OAJ30545.1 - 0.14 11.3 0.3 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 OAJ30545.1 - 0.16 11.3 2.4 4.9 6.4 0.2 2.7 3 0 0 3 3 2 0 KaiC PRK PF00485.18 OAJ30545.1 - 0.18 11.5 0.5 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 OAJ30545.1 - 0.21 11.5 1.2 6.2 6.7 0.0 3.3 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.6 OAJ30545.1 - 0.39 10.9 8.0 0.4 10.9 0.3 3.8 4 0 0 4 4 3 0 AAA domain AAA_24 PF13479.6 OAJ30545.1 - 0.63 9.7 1.7 8.9 6.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.20 OAJ30546.1 - 3.9e-29 101.3 4.7 1.5e-24 86.1 0.0 2.7 2 1 0 3 3 3 2 Hsp70 protein DUF4726 PF15855.5 OAJ30546.1 - 0.027 14.7 0.6 0.027 14.7 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) ATF7IP_BD PF16788.5 OAJ30546.1 - 0.12 12.5 4.5 0.34 11.0 4.5 1.7 1 0 0 1 1 1 0 ATF-interacting protein binding domain Prefoldin PF02996.17 OAJ30546.1 - 2.1 8.3 4.3 2.3 8.1 0.1 3.0 3 1 2 5 5 5 0 Prefoldin subunit Glyco_transf_20 PF00982.21 OAJ30547.1 - 3.2e-142 474.6 0.0 6.8e-131 437.2 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 OAJ30547.1 - 4.6e-74 248.5 0.0 7.4e-74 247.8 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 OAJ30547.1 - 0.00012 21.9 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 OAJ30547.1 - 0.0016 18.0 0.1 0.009 15.6 0.0 2.0 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase rve_3 PF13683.6 OAJ30547.1 - 0.002 17.9 0.0 0.0057 16.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Protamine_P2 PF00841.19 OAJ30547.1 - 0.29 11.7 6.5 1 9.9 6.5 1.9 1 0 0 1 1 1 0 Sperm histone P2 SUIM_assoc PF16619.5 OAJ30547.1 - 2.4 8.3 13.8 0.17 12.0 6.2 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GMC_oxred_N PF00732.19 OAJ30548.1 - 4.7e-61 206.7 0.0 1.1e-60 205.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ30548.1 - 3.8e-28 98.8 0.1 7.8e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 OAJ30548.1 - 7e-05 22.6 0.2 0.00011 22.0 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ30548.1 - 7.4e-05 22.0 0.0 0.00057 19.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ30548.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ30548.1 - 0.0003 20.1 0.0 0.014 14.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 OAJ30548.1 - 0.00038 19.6 0.2 0.00057 19.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 OAJ30548.1 - 0.0014 17.9 0.3 0.045 13.0 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ30548.1 - 0.021 13.5 0.4 0.05 12.3 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 OAJ30548.1 - 0.022 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 OAJ30548.1 - 0.12 11.6 0.0 4.8 6.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAJ30548.1 - 0.15 12.6 0.2 3.3 8.3 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Dynactin_p62 PF05502.13 OAJ30549.1 - 2.8e-50 171.5 15.2 1.5e-38 132.8 8.4 3.1 3 1 0 3 3 3 2 Dynactin p62 family UbiA PF01040.18 OAJ30550.1 - 1e-47 162.6 24.8 3.2e-46 157.7 20.7 2.2 2 0 0 2 2 2 2 UbiA prenyltransferase family R3H PF01424.22 OAJ30551.1 - 4.2e-14 52.3 0.2 6.7e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 R3H domain FliN_N PF16973.5 OAJ30551.1 - 0.18 11.6 0.4 0.18 11.6 0.4 1.8 2 0 0 2 2 2 0 Flagellar motor switch protein FliN N-terminal DER1 PF04511.15 OAJ30553.1 - 8.7e-48 162.8 2.5 9.9e-48 162.6 2.5 1.0 1 0 0 1 1 1 1 Der1-like family CitMHS PF03600.16 OAJ30553.1 - 0.06 12.5 0.5 0.07 12.3 0.5 1.2 1 0 0 1 1 1 0 Citrate transporter DUF2070 PF09843.9 OAJ30553.1 - 0.072 11.4 3.0 0.08 11.2 3.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Usp PF00582.26 OAJ30555.1 - 2.1e-19 70.4 6.8 5.1e-19 69.2 0.1 3.3 3 0 0 3 3 3 2 Universal stress protein family HSP70 PF00012.20 OAJ30556.1 - 5.1e-157 523.7 0.1 6.5e-157 523.3 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ30556.1 - 2.4e-08 33.2 0.1 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Not1 PF04054.15 OAJ30557.1 - 5.1e-117 390.9 0.0 1.7e-116 389.2 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 OAJ30557.1 - 2.9e-95 317.9 0.0 5.7e-94 313.7 0.2 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 OAJ30557.1 - 3.5e-57 192.5 3.6 7.1e-57 191.5 3.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 OAJ30557.1 - 7.9e-54 181.7 0.2 2.3e-53 180.2 0.2 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 OAJ30557.1 - 1.8e-45 154.7 1.8 1.8e-45 154.7 1.8 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat FerA PF08165.11 OAJ30557.1 - 0.091 12.7 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 FerA (NUC095) domain ERAP1_C PF11838.8 OAJ30559.1 - 5.8e-69 233.0 0.2 9.2e-69 232.4 0.2 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 OAJ30559.1 - 7.8e-64 215.2 0.0 1.3e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 OAJ30559.1 - 4.3e-39 134.6 0.0 1.8e-35 122.8 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Tht1 PF04163.12 OAJ30560.1 - 0.031 13.1 2.7 0.12 11.1 0.0 2.0 1 1 1 2 2 2 0 Tht1-like nuclear fusion protein Hypoth_Ymh PF09509.10 OAJ30560.1 - 0.094 12.6 2.7 0.32 10.9 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) NusB PF01029.18 OAJ30560.1 - 0.99 9.6 9.8 8.8 6.6 0.2 3.8 3 1 1 4 4 4 0 NusB family CAF1 PF04857.20 OAJ30560.1 - 3.7 6.6 6.3 3.7 6.6 5.4 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease GrpE PF01025.19 OAJ30560.1 - 7.2 6.2 11.6 0.19 11.4 1.9 2.2 2 0 0 2 2 2 0 GrpE TFIIA PF03153.13 OAJ30560.1 - 8.6 6.2 11.7 13 5.7 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nnf1 PF03980.14 OAJ30561.1 - 3e-08 34.0 6.1 3e-08 34.0 6.1 2.2 2 1 0 2 2 2 1 Nnf1 Csm1_N PF18504.1 OAJ30561.1 - 0.037 14.4 1.9 0.037 14.4 1.9 2.7 3 1 0 3 3 3 0 Csm1 N-terminal domain ZapB PF06005.12 OAJ30561.1 - 0.12 12.9 14.9 0.98 9.9 7.6 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Syntaxin-6_N PF09177.11 OAJ30561.1 - 1.4 9.5 6.5 0.49 11.0 2.3 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.13 OAJ30561.1 - 2.4 7.3 5.7 2.7 7.2 3.5 1.9 2 0 0 2 2 2 0 TMPIT-like protein USP8_interact PF08941.10 OAJ30561.1 - 3.4 7.5 8.3 1.1 9.1 3.2 2.4 3 0 0 3 3 3 0 USP8 interacting IFT20 PF14931.6 OAJ30561.1 - 3.6 7.8 10.7 0.3 11.3 4.5 2.5 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 YabA PF06156.13 OAJ30561.1 - 9.5 6.9 9.2 15 6.3 0.0 2.8 2 1 0 2 2 2 0 Initiation control protein YabA Med6 PF04934.14 OAJ30562.1 - 8.4e-40 135.6 0.0 1.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component RNA_pol_3_Rpc31 PF11705.8 OAJ30562.1 - 0.00068 20.0 1.2 0.039 14.2 0.6 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 OAJ30562.1 - 0.19 11.6 2.1 0.28 11.0 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 OAJ30562.1 - 0.33 10.6 5.2 0.49 10.1 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 OAJ30562.1 - 6.1 7.3 14.3 4.4 7.8 12.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Rad10 PF03834.14 OAJ30563.1 - 4.3e-49 165.3 0.2 7.1e-49 164.6 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 OAJ30563.1 - 3.8e-07 30.6 0.0 1.4e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OAJ30563.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif EF1_GNE PF00736.19 OAJ30563.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain RasGAP PF00616.19 OAJ30565.1 - 8.2e-59 198.8 0.0 1.6e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 OAJ30565.1 - 6.7e-40 136.4 0.1 2.2e-39 134.7 0.1 2.0 1 0 0 1 1 1 1 RasGAP C-terminus YabA PF06156.13 OAJ30565.1 - 0.14 12.8 0.4 49 4.6 0.2 3.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF2418 PF10332.9 OAJ30566.1 - 1.1e-19 70.8 0.9 1.1e-19 70.8 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) YL1 PF05764.13 OAJ30566.1 - 0.044 13.9 9.5 0.072 13.2 9.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Pox_Ag35 PF03286.14 OAJ30566.1 - 0.06 13.1 2.8 0.11 12.3 2.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 OAJ30566.1 - 0.075 12.9 3.2 0.14 12.0 3.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nucleo_P87 PF07267.11 OAJ30566.1 - 0.16 10.8 3.1 0.23 10.3 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 OAJ30566.1 - 0.37 10.4 5.1 0.81 9.3 5.1 1.5 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 OAJ30566.1 - 0.75 10.1 8.5 1.6 9.0 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 OAJ30566.1 - 4.1 6.7 12.7 5.9 6.1 12.7 1.1 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 OAJ30566.1 - 5 6.2 5.9 8.1 5.6 5.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cwf_Cwc_15 PF04889.12 OAJ30566.1 - 5.6 6.6 12.6 0.093 12.4 5.2 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ferric_reduct PF01794.19 OAJ30568.1 - 6.6e-17 61.8 9.7 6.6e-17 61.8 9.7 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 OAJ30568.1 - 5.4e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 OAJ30568.1 - 3.2e-06 27.2 0.0 0.0001 22.3 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 OAJ30568.1 - 0.021 15.5 0.0 0.29 11.8 0.0 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 OAJ30568.1 - 0.028 15.0 8.7 1.7 9.2 1.9 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) PCRF PF03462.18 OAJ30569.1 - 4e-51 173.6 0.0 1.1e-50 172.3 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 OAJ30569.1 - 1.9e-36 124.5 1.6 4.9e-36 123.2 1.6 1.7 1 0 0 1 1 1 1 RF-1 domain Ald_Xan_dh_C2 PF02738.18 OAJ30570.1 - 3.9e-185 616.5 0.0 5.4e-185 616.0 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 OAJ30570.1 - 2e-30 105.4 0.0 4.9e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 OAJ30570.1 - 5.9e-28 97.7 0.0 1.2e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 OAJ30570.1 - 2.9e-24 84.9 0.1 6.2e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 OAJ30570.1 - 2.4e-20 72.6 1.0 1.4e-19 70.1 0.0 2.8 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 OAJ30570.1 - 1.8e-06 27.8 0.1 2.2e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Med8 PF10232.9 OAJ30571.1 - 0.0063 16.1 0.0 0.11 12.1 0.0 2.6 1 1 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 4HBT PF03061.22 OAJ30572.1 - 2.1e-09 37.6 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 OAJ30572.1 - 0.039 14.1 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) NOA36 PF06524.12 OAJ30573.1 - 0.012 15.0 7.9 0.012 15.0 7.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 OAJ30573.1 - 0.085 13.1 6.0 0.089 13.0 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 OAJ30573.1 - 0.13 11.4 12.3 0.13 11.4 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 OAJ30573.1 - 0.15 12.1 2.8 0.14 12.1 2.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 OAJ30573.1 - 0.37 10.5 3.3 0.42 10.3 3.3 1.1 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 OAJ30573.1 - 0.51 8.6 3.6 0.52 8.5 3.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 OAJ30573.1 - 0.53 10.0 11.4 0.53 10.0 11.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 OAJ30573.1 - 0.68 10.4 16.1 0.87 10.0 16.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GCIP PF13324.6 OAJ30573.1 - 1.6 8.3 7.2 1.7 8.2 7.2 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Imm5 PF14423.6 OAJ30573.1 - 1.9 8.7 5.1 2 8.6 5.1 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 RRN3 PF05327.11 OAJ30573.1 - 2.7 6.4 5.6 2.7 6.4 5.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 OAJ30573.1 - 3 5.9 12.5 3.4 5.7 12.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi ANAPC9 PF12856.7 OAJ30573.1 - 3.4 7.9 7.4 4.3 7.6 7.4 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 PBP1_TM PF14812.6 OAJ30573.1 - 4.2 7.8 13.4 4.8 7.6 13.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WLM PF08325.10 OAJ30574.1 - 2.5e-48 164.7 1.7 3.3e-48 164.3 0.0 2.0 3 1 0 3 3 3 1 WLM domain zf-RanBP PF00641.18 OAJ30574.1 - 4.9e-06 25.7 3.2 8.1e-06 25.1 3.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 OAJ30574.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 PhdYeFM_antitox PF02604.19 OAJ30574.1 - 0.11 12.3 0.4 0.28 11.0 0.4 1.6 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system UvrD-helicase PF00580.21 OAJ30575.1 - 3.6e-68 230.4 0.3 6.9e-68 229.5 0.3 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 OAJ30575.1 - 7.9e-58 196.5 0.0 3.9e-28 98.8 0.0 3.3 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 OAJ30575.1 - 7e-31 107.5 0.0 1.6e-30 106.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 OAJ30575.1 - 8e-11 41.6 0.1 3.2e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 OAJ30575.1 - 1.3e-05 25.1 0.1 0.22 11.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 OAJ30575.1 - 0.0012 18.4 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_12 PF13087.6 OAJ30575.1 - 0.14 11.7 0.0 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2868 PF11067.8 OAJ30575.1 - 9.4 5.6 9.2 0.35 10.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2868) LAG1-DNAbind PF09271.11 OAJ30576.1 - 1e-30 107.4 1.6 4.9e-30 105.2 0.0 2.5 2 0 0 2 2 2 1 LAG1, DNA binding BTD PF09270.10 OAJ30576.1 - 6.8e-06 26.4 0.0 2.1e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4616 PF15394.6 OAJ30576.1 - 0.1 11.5 1.4 0.2 10.6 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) KTI12 PF08433.10 OAJ30577.1 - 6.1e-55 186.6 0.0 1e-54 185.8 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 OAJ30577.1 - 1.7e-08 34.7 0.4 5.1e-08 33.2 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ30577.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Transket_pyr PF02779.24 OAJ30578.1 - 6.6e-47 159.5 0.5 9.5e-47 159.0 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 OAJ30578.1 - 7.8e-40 135.6 0.2 3.6e-39 133.5 0.0 2.2 2 1 0 2 2 2 1 Transketolase, C-terminal domain HNF-1_N PF04814.13 OAJ30578.1 - 0.0038 17.9 1.8 0.0064 17.1 1.8 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus Tannase PF07519.11 OAJ30580.1 - 1.8e-63 215.1 0.3 6.7e-63 213.2 0.3 1.7 1 1 0 1 1 1 1 Tannase and feruloyl esterase UAA PF08449.11 OAJ30582.1 - 2.2e-10 40.2 13.0 5.4e-06 25.8 0.9 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 OAJ30582.1 - 0.00046 20.4 4.2 0.00046 20.4 4.2 2.7 2 1 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.20 OAJ30582.1 - 0.011 14.9 1.0 0.011 14.9 1.0 2.4 2 1 0 2 2 2 0 Phosphate transporter family Peptidase_M30 PF10460.9 OAJ30582.1 - 0.072 12.0 0.2 0.1 11.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase M30 zf-RING_UBOX PF13445.6 OAJ30583.1 - 4.1e-07 29.9 6.6 4.1e-07 29.9 6.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ30583.1 - 1.3e-06 28.1 5.8 1.3e-06 28.1 5.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ30583.1 - 4.3e-06 26.5 7.2 2.4e-05 24.1 3.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ30583.1 - 6.4e-06 25.9 4.7 6.4e-06 25.9 4.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ30583.1 - 1.2e-05 25.6 10.1 1.5e-05 25.2 4.0 2.6 3 0 0 3 3 3 1 Ring finger domain DUF1644 PF07800.12 OAJ30583.1 - 0.00012 22.1 1.8 0.021 14.9 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1644) zf-RING_5 PF14634.6 OAJ30583.1 - 0.00034 20.5 5.7 0.00034 20.5 5.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ30583.1 - 0.00042 20.1 6.9 0.0068 16.3 4.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ30583.1 - 0.0023 18.0 5.7 0.0023 18.0 5.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 OAJ30583.1 - 1.4 9.0 3.9 3.8 7.6 1.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 OAJ30583.1 - 2.6 7.9 6.3 5.8 6.8 6.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger Aldedh PF00171.22 OAJ30584.1 - 1.9e-71 241.0 0.0 2.3e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MOSC_N PF03476.16 OAJ30585.1 - 0.44 10.4 3.0 5 7.0 0.1 3.3 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain DFRP_C PF16543.5 OAJ30586.1 - 1.6e-28 99.0 3.1 1.6e-28 99.0 3.1 4.1 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH_3 PF15663.5 OAJ30586.1 - 0.0045 17.2 4.6 0.039 14.2 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger containing family Torus PF16131.5 OAJ30586.1 - 0.31 11.7 11.6 17 6.2 0.0 4.2 3 1 0 3 3 3 0 Torus domain Cwf_Cwc_15 PF04889.12 OAJ30586.1 - 0.92 9.2 28.3 0.13 12.0 15.0 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-CCCH_2 PF14608.6 OAJ30586.1 - 2.2 8.9 9.7 8.5 7.0 1.4 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Lyase_1 PF00206.20 OAJ30587.1 - 1.1e-92 310.8 0.0 1.7e-92 310.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 OAJ30587.1 - 4.1e-25 88.3 0.1 1e-24 87.1 0.1 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF726 PF05277.12 OAJ30588.1 - 2e-63 214.4 5.3 2.8e-63 213.9 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MFS_1 PF07690.16 OAJ30589.1 - 1.8e-26 92.9 30.5 1.8e-26 92.9 30.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 OAJ30589.1 - 0.0031 17.3 0.1 0.0031 17.3 0.1 3.3 4 1 0 4 4 4 1 SRP-independent targeting protein 2/TMEM208 FAM176 PF14851.6 OAJ30589.1 - 0.085 12.5 3.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Cnd2 PF05786.14 OAJ30589.1 - 1.8 7.1 14.9 2.5 6.6 1.8 2.1 2 0 0 2 2 2 0 Condensin complex subunit 2 HisG PF01634.18 OAJ30590.1 - 1.5e-41 142.0 0.0 2.9e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 OAJ30590.1 - 3.7e-26 91.1 0.1 7e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain SBP_bac_3 PF00497.20 OAJ30590.1 - 0.1 12.0 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 PMI_typeI PF01238.21 OAJ30591.1 - 1.6e-53 182.3 0.0 1.1e-52 179.5 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I Ytp1 PF10355.9 OAJ30592.1 - 9.1e-49 166.1 24.4 6.9e-46 156.7 24.4 3.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 OAJ30592.1 - 7.1e-24 83.6 3.8 7.1e-24 83.6 3.8 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF2427) Arc_PepC_II PF06847.11 OAJ30593.1 - 0.23 12.0 0.4 0.41 11.2 0.4 1.4 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Nop14 PF04147.12 OAJ30593.1 - 5.3 5.1 9.4 6.3 4.9 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 OAJ30593.1 - 9 4.7 5.2 10 4.5 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Chromo PF00385.24 OAJ30595.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain T2SSF PF00482.23 OAJ30595.1 - 1.3 9.0 4.4 3 7.8 4.4 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Homeobox_KN PF05920.11 OAJ30596.1 - 1.7e-17 63.0 3.5 3.2e-17 62.1 3.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 OAJ30596.1 - 5.9e-05 22.8 2.0 0.00015 21.5 1.1 2.0 2 0 0 2 2 2 1 Homeodomain MFS_1 PF07690.16 OAJ30597.1 - 3.2e-26 92.1 86.8 7.2e-21 74.5 48.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PI3_PI4_kinase PF00454.27 OAJ30598.1 - 4.6e-34 118.3 0.0 9.8e-32 110.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 OAJ30598.1 - 2.4e-26 92.3 0.2 7.9e-26 90.6 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Utp14 PF04615.13 OAJ30600.1 - 4e-170 568.0 43.5 4e-170 568.0 43.5 2.5 1 1 2 3 3 3 1 Utp14 protein UPF0113_N PF17833.1 OAJ30601.1 - 4.6e-27 94.4 0.0 6.9e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 OAJ30601.1 - 2.9e-23 81.9 0.0 4.5e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 OAJ30601.1 - 0.051 13.6 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain HMGL-like PF00682.19 OAJ30602.1 - 3.4e-81 272.7 0.5 6.2e-81 271.8 0.5 1.4 1 0 0 1 1 1 1 HMGL-like GAD PF02938.14 OAJ30602.1 - 0.066 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 GAD domain NUC173 PF08161.12 OAJ30603.1 - 1.8e-46 158.4 0.1 8.7e-46 156.2 0.0 2.3 2 0 0 2 2 2 1 NUC173 domain MMS19_C PF12460.8 OAJ30603.1 - 0.0015 17.7 20.4 0.0052 16.0 3.0 3.5 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal MFMR PF07777.11 OAJ30603.1 - 1.7 9.2 3.2 3.7 8.1 0.0 3.1 4 0 0 4 4 4 0 G-box binding protein MFMR CDC73_C PF05179.14 OAJ30604.1 - 2.9e-45 153.8 0.0 9.4e-31 106.6 0.3 2.2 2 0 0 2 2 2 2 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 OAJ30604.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Prenyltrans PF00432.21 OAJ30606.1 - 1.5e-28 98.2 10.1 1.3e-07 31.2 0.0 5.6 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 OAJ30606.1 - 0.00071 18.8 0.0 0.62 9.1 0.0 2.3 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain AKAP2_C PF15304.6 OAJ30606.1 - 0.0046 16.3 0.2 0.0046 16.3 0.2 1.9 3 0 0 3 3 3 1 A-kinase anchor protein 2 C-terminus Cullin PF00888.22 OAJ30607.1 - 0.03 12.9 0.0 0.12 11.0 0.0 1.8 1 1 0 1 1 1 0 Cullin family TAF4 PF05236.14 OAJ30607.1 - 0.14 11.8 0.3 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ABC_tran PF00005.27 OAJ30608.1 - 6.8e-43 146.5 0.0 1.2e-20 74.4 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ30608.1 - 4.4e-24 84.3 2.3 4.4e-24 84.3 2.3 2.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 OAJ30608.1 - 3.7e-13 49.4 0.1 7.6e-06 25.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ30608.1 - 6.4e-13 49.2 5.3 0.0026 17.6 0.3 4.6 4 1 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ30608.1 - 1.3e-06 28.0 0.1 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ30608.1 - 6.7e-06 26.2 0.6 0.021 14.9 0.1 3.2 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ30608.1 - 1.5e-05 25.3 0.1 0.13 12.5 0.1 3.3 4 1 0 4 4 2 2 AAA domain DUF87 PF01935.17 OAJ30608.1 - 0.00023 21.4 2.5 0.036 14.2 0.0 3.5 3 1 0 3 3 3 1 Helicase HerA, central domain NACHT PF05729.12 OAJ30608.1 - 0.00027 20.9 0.4 0.24 11.3 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_33 PF13671.6 OAJ30608.1 - 0.00037 20.7 1.1 1.6 8.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 OAJ30608.1 - 0.00041 20.3 0.1 0.16 11.8 0.0 2.6 2 1 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 OAJ30608.1 - 0.00041 20.6 0.8 1.1 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OAJ30608.1 - 0.00073 19.3 0.0 0.44 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ30608.1 - 0.0009 19.6 0.0 0.077 13.4 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 OAJ30608.1 - 0.0022 17.8 3.5 0.34 10.6 0.0 3.5 3 1 1 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 OAJ30608.1 - 0.0073 16.8 8.8 0.24 11.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 OAJ30608.1 - 0.0098 15.9 0.0 3.9 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 OAJ30608.1 - 0.014 14.4 0.0 3 6.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OAJ30608.1 - 0.019 15.3 5.2 1.5 9.2 0.0 3.4 4 0 0 4 4 3 0 AAA ATPase domain AAA_18 PF13238.6 OAJ30608.1 - 0.03 14.9 0.1 1 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF287 PF03384.14 OAJ30608.1 - 0.042 14.2 0.3 0.19 12.1 0.1 2.2 2 0 0 2 2 1 0 Drosophila protein of unknown function, DUF287 T2SSE PF00437.20 OAJ30608.1 - 0.049 12.7 0.0 0.86 8.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 OAJ30608.1 - 0.049 13.0 0.0 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 OAJ30608.1 - 0.054 13.4 0.0 9.5 6.1 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 OAJ30608.1 - 0.057 12.9 0.0 0.93 9.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 OAJ30608.1 - 0.068 12.8 0.1 12 5.4 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 OAJ30608.1 - 0.08 12.5 0.0 12 5.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 OAJ30608.1 - 0.15 11.8 5.8 0.76 9.5 0.2 3.8 3 2 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 OAJ30608.1 - 0.37 10.8 4.4 1.7 8.7 0.0 3.2 4 0 0 4 4 3 0 Dynamin family DUF1746 PF08508.10 OAJ30609.1 - 1.7e-16 60.6 2.0 3.5e-16 59.6 2.0 1.5 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) 2OG-FeII_Oxy PF03171.20 OAJ30610.1 - 1.7e-22 79.8 0.0 2.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAJ30610.1 - 2.6e-21 76.6 0.0 4.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PAC4 PF16093.5 OAJ30611.1 - 2.8e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 zf-H2C2_2 PF13465.6 OAJ30612.1 - 4.2e-09 36.4 5.8 1.7e-08 34.5 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 OAJ30612.1 - 3.2e-05 24.2 14.0 0.00011 22.5 0.8 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 OAJ30612.1 - 4e-05 24.2 11.4 0.15 12.7 1.1 3.6 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 OAJ30612.1 - 0.0014 19.3 0.9 0.0014 19.3 0.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ30612.1 - 0.0015 18.4 0.5 0.0015 18.4 0.5 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 OAJ30612.1 - 0.43 10.7 1.5 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf_ZIC PF18366.1 OAJ30612.1 - 8.9 6.5 6.6 6 7.1 0.3 3.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain MRP-L46 PF11788.8 OAJ30613.1 - 6.8e-19 68.8 0.3 2.8e-18 66.8 0.1 2.2 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 YjfB_motility PF14070.6 OAJ30613.1 - 0.14 12.3 6.8 0.29 11.3 0.0 2.6 2 0 0 2 2 2 0 Putative motility protein Tautomerase PF01361.21 OAJ30613.1 - 0.35 10.8 1.4 7.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Tautomerase enzyme Response_reg PF00072.24 OAJ30614.1 - 2.5e-07 30.9 0.0 2.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Response regulator receiver domain Symplekin_C PF12295.8 OAJ30615.1 - 4.8e-55 186.5 0.4 1e-54 185.5 0.1 1.7 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 OAJ30615.1 - 4.8e-35 121.2 0.1 9.9e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 OAJ30615.1 - 0.0088 16.4 1.8 0.85 10.1 0.1 3.8 3 0 0 3 3 3 1 HEAT repeats zf-CCCH PF00642.24 OAJ30616.1 - 8.9e-24 82.9 32.2 7.6e-07 28.9 0.2 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ30616.1 - 1.4e-20 72.6 34.0 3.6e-06 26.8 3.0 5.6 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 OAJ30616.1 - 5e-11 43.3 24.0 0.00018 22.2 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 OAJ30616.1 - 2.8e-06 27.0 0.8 2.8e-06 27.0 0.8 5.2 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCHC PF00098.23 OAJ30616.1 - 3.8e-06 26.7 1.3 3.8e-06 26.7 1.3 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_3 PF15663.5 OAJ30616.1 - 0.0004 20.6 12.8 0.013 15.7 0.1 3.7 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCHC_3 PF13917.6 OAJ30616.1 - 0.016 15.1 3.8 0.044 13.8 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle Acetyltransf_1 PF00583.25 OAJ30621.1 - 4.5e-14 52.7 0.0 8.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ30621.1 - 1.2e-09 38.2 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ30621.1 - 5.5e-08 33.1 0.0 8.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ30621.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 OAJ30621.1 - 2.2e-05 24.2 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 OAJ30621.1 - 4.8e-05 23.4 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ30621.1 - 0.00024 21.8 0.0 0.00047 20.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 OAJ30621.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CtaG_Cox11 PF04442.14 OAJ30622.1 - 1.2e-55 187.7 0.0 1.8e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ipi1_N PF12333.8 OAJ30623.1 - 1.8e-13 51.0 2.1 6.4e-13 49.2 0.0 3.2 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation PBP1_TM PF14812.6 OAJ30623.1 - 0.051 14.0 0.8 0.14 12.6 0.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HEAT_2 PF13646.6 OAJ30623.1 - 0.077 13.4 0.3 0.39 11.1 0.1 2.3 2 0 0 2 2 2 0 HEAT repeats Sec3_C PF09763.9 OAJ30624.1 - 1.4e-85 288.1 0.0 1.2e-84 285.1 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 OAJ30624.1 - 5.5e-18 64.9 0.0 1e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 OAJ30624.1 - 0.035 12.9 0.2 0.051 12.3 0.2 1.2 1 0 0 1 1 1 0 Vps52 / Sac2 family RCC1 PF00415.18 OAJ30625.1 - 2.2e-22 79.4 13.7 4.5e-08 33.6 0.4 8.3 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ30625.1 - 4.5e-13 48.6 19.0 5.9e-08 32.3 1.3 6.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF676 PF05057.14 OAJ30626.1 - 0.0037 16.8 0.0 0.0073 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 OAJ30626.1 - 0.044 14.4 5.0 0.12 13.0 5.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family CwsA PF10814.8 OAJ30626.1 - 0.12 12.5 1.2 2.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA SLATT_1 PF18181.1 OAJ30626.1 - 0.16 11.9 0.3 0.42 10.5 0.3 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 PGAP1 PF07819.13 OAJ30626.1 - 0.37 10.5 2.3 1.2 8.8 2.3 1.8 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ30626.1 - 3.1 7.0 6.3 0.52 9.5 0.4 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 SAP PF02037.27 OAJ30627.1 - 3.8e-10 39.3 0.4 6.2e-10 38.6 0.4 1.4 1 0 0 1 1 1 1 SAP domain HAGH_C PF16123.5 OAJ30628.1 - 6.4e-19 68.2 0.0 1.2e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 OAJ30628.1 - 5.6e-10 39.6 2.7 2.7e-07 30.8 2.7 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 OAJ30628.1 - 0.0034 16.9 0.3 0.0087 15.6 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ADH_zinc_N_2 PF13602.6 OAJ30629.1 - 2.6e-10 41.5 0.0 6.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ30629.1 - 0.0002 21.2 0.3 0.0004 20.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ30629.1 - 0.0015 18.5 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4150 PF13665.6 OAJ30629.1 - 0.027 14.6 0.4 20 5.4 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4150) Prefoldin_3 PF13758.6 OAJ30630.1 - 0.045 13.8 0.5 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit AKNA PF12443.8 OAJ30630.1 - 0.099 13.3 0.5 0.23 12.1 0.2 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF4407 PF14362.6 OAJ30630.1 - 1.5 8.1 8.0 3.6 6.9 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GET2 PF08690.10 OAJ30631.1 - 8.7e-11 42.0 0.0 3.9e-06 26.8 0.0 2.5 2 1 0 2 2 2 2 GET complex subunit GET2 TPT PF03151.16 OAJ30632.1 - 1.7e-24 86.7 13.7 2.2e-24 86.4 13.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ30632.1 - 1.1e-10 41.8 22.6 2.4e-05 24.5 7.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 OAJ30632.1 - 4.4e-05 22.9 14.1 4.4e-05 22.9 14.1 1.5 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 OAJ30632.1 - 0.29 10.3 18.3 0.28 10.4 15.7 2.0 1 1 0 1 1 1 0 UAA transporter family Thiolase_N PF00108.23 OAJ30633.1 - 8.9e-93 310.4 2.8 1.4e-92 309.8 2.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ30633.1 - 2.4e-43 146.7 1.6 4e-42 142.7 0.5 2.5 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ30633.1 - 4.9e-07 29.6 2.4 1.8e-05 24.5 1.2 2.6 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 OAJ30633.1 - 2.7 7.9 9.6 2.9 7.8 0.2 3.8 3 1 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EBV-NA1 PF02905.14 OAJ30634.1 - 1.8 8.4 3.7 1.2 9.0 0.2 2.0 1 1 1 2 2 2 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain SRPRB PF09439.10 OAJ30635.1 - 1.2e-09 37.9 0.0 2.6e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 OAJ30635.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF374 PF04028.13 OAJ30635.1 - 0.013 15.0 0.6 0.047 13.3 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF374) AAA_16 PF13191.6 OAJ30635.1 - 0.024 15.0 1.9 0.16 12.4 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 OAJ30635.1 - 0.033 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 OAJ30635.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 OAJ30635.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ30635.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.12 OAJ30635.1 - 0.27 10.5 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EAP30 PF04157.16 OAJ30636.1 - 4.5e-55 186.5 0.0 5.6e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Cellulase PF00150.18 OAJ30637.1 - 6.4e-07 29.1 1.7 1.4e-06 28.0 1.7 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 OAJ30638.1 - 4.7e-06 26.2 1.6 8.6e-06 25.4 1.6 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L30_N PF08079.12 OAJ30639.1 - 3.5e-28 97.6 16.2 3.5e-28 97.6 16.2 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 OAJ30639.1 - 1.5e-16 60.0 1.9 1.6e-16 59.9 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rep_Org_C PF06926.11 OAJ30639.1 - 0.083 13.2 0.7 0.15 12.4 0.7 1.4 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Ribosomal_L16 PF00252.18 OAJ30640.1 - 2.3e-41 140.9 0.0 3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RNase_PH PF01138.21 OAJ30641.1 - 6.6e-07 29.9 1.4 1.3e-06 29.0 1.4 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 3HCDH_N PF02737.18 OAJ30642.1 - 1.4e-44 152.1 0.2 6.8e-44 149.9 0.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 OAJ30642.1 - 4.4e-35 120.2 0.0 9.3e-35 119.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF2680 PF10925.8 OAJ30642.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) DUF2813 PF11398.8 OAJ30642.1 - 0.22 10.8 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) FAD_binding_1 PF00667.20 OAJ30643.1 - 9.7e-55 185.5 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 OAJ30643.1 - 2.2e-06 27.8 0.0 8.3e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 OAJ30643.1 - 4.1e-06 27.4 0.0 1.7e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 OAJ30643.1 - 0.053 13.8 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II AP_endonuc_2 PF01261.24 OAJ30644.1 - 8.4e-14 51.5 0.0 1.6e-06 27.7 0.0 2.7 3 0 0 3 3 3 2 Xylose isomerase-like TIM barrel Proteasome PF00227.26 OAJ30645.1 - 1.3e-58 197.7 0.0 1.8e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ30645.1 - 9.9e-14 50.7 0.5 1.8e-13 49.9 0.2 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LSM PF01423.22 OAJ30646.1 - 3.6e-14 52.2 0.1 4.6e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ30646.1 - 0.0039 17.3 0.0 0.0055 16.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 OAJ30646.1 - 0.042 13.9 0.0 0.059 13.5 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Aminotran_1_2 PF00155.21 OAJ30647.1 - 6.7e-44 150.5 0.0 6.7e-43 147.2 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 OAJ30647.1 - 0.012 14.4 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 OAJ30647.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 OAJ30647.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 OAJ30647.1 - 0.055 12.0 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-C2H2 PF00096.26 OAJ30648.1 - 3.2e-06 27.3 18.4 7.5e-05 23.0 1.9 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ30648.1 - 0.00024 21.4 2.1 0.00024 21.4 2.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ30648.1 - 0.00086 20.0 1.2 0.00086 20.0 1.2 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ30648.1 - 0.003 17.5 0.1 0.0076 16.2 0.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ30648.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 OAJ30648.1 - 0.06 13.8 0.2 0.06 13.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 OAJ30648.1 - 0.076 13.7 11.6 0.11 13.2 0.3 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 OAJ30648.1 - 0.84 9.6 3.2 0.7 9.9 1.6 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MULE PF10551.9 OAJ30651.1 - 6.8e-08 32.8 0.2 2.9e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 OAJ30651.1 - 4.7e-05 23.0 2.0 0.00016 21.3 2.0 1.9 1 0 0 1 1 1 1 SWIM zinc finger HTH_Tnp_ISL3 PF13542.6 OAJ30651.1 - 0.055 12.9 0.2 0.15 11.5 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DDE_Tnp_IS240 PF13610.6 OAJ30651.1 - 0.099 12.9 0.1 10 6.4 0.0 2.9 3 0 0 3 3 3 0 DDE domain Sporozoite_P67 PF05642.11 OAJ30651.1 - 0.32 9.0 3.3 0.49 8.4 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FSA_C PF10479.9 OAJ30651.1 - 2.3 6.3 7.6 3.7 5.6 7.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RAP1 PF07218.11 OAJ30651.1 - 4.6 5.4 4.9 6.7 4.9 4.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M16_C PF05193.21 OAJ30652.1 - 4.9e-20 72.3 0.0 6.9e-16 58.8 0.0 3.1 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 OAJ30652.1 - 8.2e-08 32.4 0.0 4.9e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Oxysterol_BP PF01237.18 OAJ30652.1 - 0.18 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Chromo PF00385.24 OAJ30654.1 - 5.5e-06 26.2 0.4 9.8e-06 25.4 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Imm5 PF14423.6 OAJ30654.1 - 0.14 12.4 1.3 0.53 10.5 1.3 2.0 1 0 0 1 1 1 0 Immunity protein Imm5 PGA2 PF07543.12 OAJ30655.1 - 0.0088 16.0 0.7 0.0088 16.0 0.7 1.6 2 0 0 2 2 2 1 Protein trafficking PGA2 SR-25 PF10500.9 OAJ30655.1 - 0.039 13.6 20.1 0.082 12.5 20.1 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_BLRF2 PF05812.12 OAJ30655.1 - 0.04 14.1 2.9 0.082 13.0 2.9 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Cwf_Cwc_15 PF04889.12 OAJ30655.1 - 0.095 12.4 11.7 0.15 11.7 11.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.9 OAJ30655.1 - 0.15 10.6 8.0 0.16 10.5 8.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF1168 PF06658.12 OAJ30655.1 - 0.2 11.5 11.2 0.49 10.2 11.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Apt1 PF10351.9 OAJ30655.1 - 0.37 9.6 8.6 0.46 9.3 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4718 PF15842.5 OAJ30655.1 - 1.2 8.9 7.2 1.7 8.4 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Presenilin PF01080.17 OAJ30655.1 - 1.6 7.4 4.2 2.3 6.9 4.2 1.2 1 0 0 1 1 1 0 Presenilin DUF755 PF05501.11 OAJ30655.1 - 3 8.1 27.5 1.3 9.3 24.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) SUR7 PF06687.12 OAJ30656.1 - 0.16 11.6 0.7 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 SUR7/PalI family Dickkopf_N PF04706.12 OAJ30656.1 - 0.23 12.0 26.2 0.048 14.1 11.1 3.6 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region Oxidored_q6 PF01058.22 OAJ30657.1 - 9.3e-23 80.5 0.1 1.4e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Nup88 PF10168.9 OAJ30659.1 - 2.6e-13 48.7 1.4 0.00037 18.5 0.0 5.0 5 0 0 5 5 5 5 Nuclear pore component ZapB PF06005.12 OAJ30659.1 - 7.8 7.0 6.9 5.4 7.5 0.1 3.2 3 0 0 3 3 3 0 Cell division protein ZapB OPT PF03169.15 OAJ30660.1 - 6.2e-190 632.9 53.3 7.1e-190 632.7 53.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pkinase PF00069.25 OAJ30661.1 - 6.2e-65 219.2 0.0 1.8e-64 217.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30661.1 - 2.5e-33 115.5 0.0 3.7e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30661.1 - 2.1e-08 33.8 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ30661.1 - 0.00082 19.4 0.2 0.00082 19.4 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 OAJ30661.1 - 0.00089 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 OAJ30661.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 OAJ30661.1 - 0.0016 17.9 0.1 0.0026 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 OAJ30661.1 - 0.071 12.7 0.2 8.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 OPT PF03169.15 OAJ30662.1 - 1.9e-189 631.3 55.5 2.2e-189 631.1 55.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NUDIX PF00293.28 OAJ30664.1 - 7.7e-13 48.6 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 OAJ30664.1 - 4.6e-10 40.1 3.2 1.8e-09 38.2 3.2 2.1 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Lipase_3 PF01764.25 OAJ30665.1 - 5.2e-14 52.3 0.0 8.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 OAJ30665.1 - 0.019 15.5 0.0 0.019 15.5 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 OAJ30665.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 OAJ30665.1 - 0.069 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TMEM171 PF15471.6 OAJ30665.1 - 0.084 11.8 4.5 4.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF3246 PF11596.8 OAJ30665.1 - 0.099 12.1 0.7 0.24 10.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2974 PF11187.8 OAJ30665.1 - 0.2 11.2 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SKN1 PF03935.15 OAJ30667.1 - 1.1e-19 70.2 0.0 1.2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ30668.1 - 3.2e-113 378.8 1.2 1.1e-75 255.0 0.7 2.1 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 OAJ30669.1 - 4.1e-65 220.1 16.3 7.5e-65 219.2 16.3 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GST_C_6 PF17171.4 OAJ30670.1 - 4.2e-09 36.1 0.0 8.5e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 OAJ30670.1 - 0.00041 20.7 0.2 0.00075 19.8 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom22 PF04281.13 OAJ30672.1 - 2.3e-38 131.1 2.6 2.1e-34 118.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 Shadoo PF14999.6 OAJ30672.1 - 0.0031 17.6 3.2 0.0052 16.9 3.2 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Retinal PF15449.6 OAJ30672.1 - 0.13 10.1 1.5 0.18 9.6 1.5 1.1 1 0 0 1 1 1 0 Retinal protein RRN3 PF05327.11 OAJ30672.1 - 0.7 8.4 6.4 0.8 8.2 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 OAJ30672.1 - 0.97 9.1 12.2 1.4 8.6 12.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CNDH2_M PF16869.5 OAJ30672.1 - 1.2 9.9 9.9 1.9 9.2 9.9 1.3 1 0 0 1 1 1 0 PF16858 DUF3295 PF11702.8 OAJ30672.1 - 1.3 8.3 8.3 1.9 7.8 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DNA_pol_phi PF04931.13 OAJ30672.1 - 1.7 6.6 8.8 1.9 6.5 8.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 OAJ30672.1 - 3.1 7.5 7.4 1 9.0 1.5 2.6 3 0 0 3 3 3 0 FAM176 family RXT2_N PF08595.11 OAJ30672.1 - 6.2 6.8 6.6 11 6.0 6.6 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 OAJ30672.1 - 6.9 6.8 13.8 9.8 6.4 13.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 OAJ30672.1 - 7.1 7.1 15.4 15 6.1 15.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Yippee-Mis18 PF03226.14 OAJ30673.1 - 3.3e-15 56.2 0.0 1.2e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TFIIA PF03153.13 OAJ30673.1 - 0.39 10.6 6.6 0.65 9.9 6.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CiPC PF15800.5 OAJ30673.1 - 5.1 6.7 19.8 9 5.9 19.8 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian SET PF00856.28 OAJ30674.1 - 3.3e-14 53.6 0.0 3.3e-14 53.6 0.0 4.1 3 2 0 4 4 4 1 SET domain AWS PF17907.1 OAJ30674.1 - 2.8e-10 40.0 7.2 5.6e-10 39.1 7.2 1.5 1 0 0 1 1 1 1 AWS domain PHD PF00628.29 OAJ30675.1 - 1.3e-05 25.0 19.0 2.2e-05 24.2 19.0 1.4 1 0 0 1 1 1 1 PHD-finger UNC-79 PF14776.6 OAJ30675.1 - 5 5.7 5.6 8.1 5.1 5.6 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 CENP-B_dimeris PF09026.10 OAJ30676.1 - 1.3 9.4 11.1 3.2 8.2 11.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L6e PF01159.19 OAJ30677.1 - 2.1e-34 118.4 0.1 2.1e-34 118.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 OAJ30677.1 - 0.0011 19.1 1.7 0.0011 19.1 1.7 2.4 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain ThiF PF00899.21 OAJ30680.1 - 2.9e-64 216.7 0.0 4e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 OAJ30680.1 - 1.5e-25 89.1 0.0 2.5e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 OAJ30680.1 - 0.0026 17.8 0.2 0.006 16.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAJ30680.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 OAJ30680.1 - 0.16 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ30680.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ecm33 PF12454.8 OAJ30680.1 - 0.27 11.4 1.9 0.51 10.5 1.9 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UBA_e1_thiolCys PF10585.9 OAJ30680.1 - 0.28 11.1 0.4 14 5.5 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site zf-Tim10_DDP PF02953.15 OAJ30681.1 - 2.4e-20 72.0 1.0 2.9e-20 71.7 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger QCR10 PF09796.9 OAJ30682.1 - 2.6e-14 53.0 0.7 4.1e-14 52.4 0.4 1.5 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 OAJ30682.1 - 0.065 13.2 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Rep_fac_C PF08542.11 OAJ30683.1 - 4.1e-25 88.0 0.0 8.2e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 OAJ30683.1 - 2.4e-12 47.4 0.0 4.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 OAJ30683.1 - 4.2e-12 46.1 0.0 3.3e-10 40.0 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 OAJ30683.1 - 3.2e-07 30.9 0.1 2.7e-05 24.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 OAJ30683.1 - 4.9e-06 26.4 0.0 8.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ30683.1 - 1.3e-05 25.3 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 OAJ30683.1 - 2.8e-05 24.4 0.1 0.052 13.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 OAJ30683.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 OAJ30683.1 - 0.00031 19.8 0.0 0.00062 18.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 OAJ30683.1 - 0.00032 20.5 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 OAJ30683.1 - 0.00085 19.6 0.1 0.28 11.5 0.0 3.0 3 0 0 3 3 3 1 AAA C-terminal domain Viral_helicase1 PF01443.18 OAJ30683.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 OAJ30683.1 - 0.0048 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ30683.1 - 0.0068 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 OAJ30683.1 - 0.0092 15.9 0.0 0.073 13.0 0.0 2.1 1 1 1 2 2 2 1 NTPase DUF5119 PF17145.4 OAJ30683.1 - 0.011 15.6 0.0 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) Mg_chelatase PF01078.21 OAJ30683.1 - 0.015 14.7 0.0 0.11 11.9 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI MipZ PF09140.11 OAJ30683.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ KTI12 PF08433.10 OAJ30683.1 - 0.03 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 OAJ30683.1 - 0.033 14.5 0.1 0.097 13.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ30683.1 - 0.034 13.5 0.0 8.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 OAJ30683.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 OAJ30683.1 - 0.038 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 OAJ30683.1 - 0.048 13.3 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 OAJ30683.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Thymidylate_kin PF02223.17 OAJ30683.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_11 PF13086.6 OAJ30683.1 - 0.12 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain B12-binding_2 PF02607.17 OAJ30683.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain DEAD PF00270.29 OAJ30683.1 - 0.14 11.9 0.1 0.47 10.2 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase DNA_pol3_delta PF06144.13 OAJ30683.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SNF2_N PF00176.23 OAJ30684.1 - 1.1e-48 165.8 0.0 1.1e-48 165.8 0.0 3.0 3 1 1 4 4 4 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ30684.1 - 1.5e-17 63.9 0.0 5.7e-17 62.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 OAJ30684.1 - 3.5e-11 42.8 0.1 3.5e-11 42.8 0.1 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 OAJ30684.1 - 1.6e-08 34.3 0.2 0.0012 18.7 0.0 3.1 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 OAJ30684.1 - 8.8e-06 25.5 5.9 0.021 14.7 0.1 2.9 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 OAJ30684.1 - 0.00073 19.2 2.3 0.00073 19.2 2.3 5.1 4 1 0 5 5 5 2 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 OAJ30684.1 - 0.22 11.7 5.0 3.7 7.7 0.1 2.9 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_4 PF16866.5 OAJ30684.1 - 3.8 7.7 8.9 22 5.2 1.7 3.6 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 OAJ30684.1 - 9 6.3 10.4 7.2 6.6 0.1 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RRM_1 PF00076.22 OAJ30685.1 - 3.2e-16 58.9 0.0 4.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ30685.1 - 3.7e-07 29.8 0.0 4.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 OAJ30686.1 - 4.3e-35 119.5 6.8 1.4e-15 57.0 0.2 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ30686.1 - 0.97 8.5 0.0 0.97 8.5 0.0 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease RAP1 PF07218.11 OAJ30686.1 - 1.5 7.0 4.3 2 6.6 4.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 OAJ30686.1 - 6.9 5.6 7.0 11 5.0 7.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X MoaE PF02391.17 OAJ30687.1 - 2.1e-36 124.6 0.0 2.9e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 MoaE protein TOM13 PF08219.11 OAJ30688.1 - 3.6e-10 39.7 1.7 7.8e-10 38.6 1.7 1.7 1 1 0 1 1 1 1 Outer membrane protein TOM13 LAT PF15234.6 OAJ30688.1 - 0.0027 17.5 0.9 0.004 16.9 0.9 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells CENP-B_dimeris PF09026.10 OAJ30688.1 - 0.021 15.2 10.7 0.041 14.3 10.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 OAJ30688.1 - 0.081 11.7 0.3 0.094 11.5 0.3 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 OAJ30688.1 - 0.13 11.6 7.3 0.16 11.2 7.3 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 OAJ30688.1 - 0.81 9.7 9.4 1.7 8.7 9.4 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 OAJ30688.1 - 0.87 9.3 4.1 1.2 8.8 4.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 OAJ30688.1 - 1.3 7.2 9.4 1.4 7.0 9.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 OAJ30688.1 - 1.4 8.3 4.6 1.8 7.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 OAJ30688.1 - 4.5 5.9 5.0 5.6 5.6 5.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 OAJ30688.1 - 4.7 6.9 8.4 9.3 5.9 8.1 1.7 1 1 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 OAJ30688.1 - 6.6 6.2 11.8 8.3 5.9 11.8 1.1 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.6 OAJ30688.1 - 7.2 7.1 10.6 16 5.9 10.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PX PF00787.24 OAJ30689.1 - 3.5e-19 68.8 0.0 6.3e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 PX domain ApbA_C PF08546.11 OAJ30692.1 - 9.4e-19 67.8 0.0 4.6e-09 36.5 0.0 3.1 4 1 0 4 4 4 2 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 OAJ30692.1 - 5.5e-16 58.6 0.0 1.3e-11 44.4 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Syd PF07348.12 OAJ30693.1 - 0.00076 19.2 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Syd protein (SUKH-2) GRDP-like PF07173.12 OAJ30694.1 - 2.9e-15 57.2 1.0 2.1e-12 47.9 0.0 3.8 3 1 1 4 4 4 1 Glycine-rich domain-containing protein-like DUF4301 PF14134.6 OAJ30694.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Acyl-CoA_ox_N PF14749.6 OAJ30695.1 - 5.5e-19 69.0 0.0 8.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 OAJ30695.1 - 0.032 14.4 0.0 0.067 13.4 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain UDPGT PF00201.18 OAJ30696.1 - 2.1e-13 49.9 0.1 3.9e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FSA_C PF10479.9 OAJ30697.1 - 0.57 8.3 1.4 0.78 7.8 1.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus F-box-like PF12937.7 OAJ30698.1 - 0.0079 16.1 0.1 0.028 14.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like Sec7 PF01369.20 OAJ30699.1 - 1.2e-65 220.6 0.0 2.1e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ30699.1 - 1.2e-10 41.5 0.0 3.8e-07 30.1 0.0 3.5 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF5067 PF16729.5 OAJ30699.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) PolyA_pol PF01743.20 OAJ30700.1 - 3.1e-23 82.6 0.0 5.3e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 OAJ30700.1 - 0.0018 18.0 0.1 0.0043 16.8 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A GWT1 PF06423.12 OAJ30701.1 - 2.4e-34 118.6 0.0 6e-22 78.4 0.0 2.9 2 0 0 2 2 2 2 GWT1 DUF4818 PF16089.5 OAJ30701.1 - 0.82 10.2 4.6 0.25 11.8 0.1 2.4 2 1 2 4 4 4 0 Domain of unknown function (DUF4818) Med5 PF08689.10 OAJ30702.1 - 4.4e-22 77.8 0.0 2e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Mediator complex subunit Med5 AMP-binding PF00501.28 OAJ30702.1 - 5.1e-12 45.1 0.1 3.8e-11 42.2 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme NUDE_C PF04880.13 OAJ30703.1 - 6.6e-14 52.8 10.7 6.6e-14 52.8 10.7 3.2 3 1 1 4 4 2 1 NUDE protein, C-terminal conserved region DUF3584 PF12128.8 OAJ30703.1 - 7.8e-06 23.7 14.9 1.1e-05 23.3 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 OAJ30703.1 - 0.00021 21.4 23.4 0.0026 17.8 3.0 2.9 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DivIC PF04977.15 OAJ30703.1 - 0.0048 16.6 14.6 0.22 11.3 0.9 3.6 2 1 1 3 3 3 2 Septum formation initiator Filament PF00038.21 OAJ30703.1 - 0.008 15.8 7.4 0.008 15.8 7.4 2.3 1 1 1 2 2 2 1 Intermediate filament protein DUF2353 PF09789.9 OAJ30703.1 - 0.034 13.5 18.6 0.029 13.7 8.3 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Laminin_II PF06009.12 OAJ30703.1 - 0.041 13.9 17.6 0.034 14.1 5.3 3.6 2 1 2 4 4 3 0 Laminin Domain II Prefoldin_2 PF01920.20 OAJ30703.1 - 0.072 13.1 23.9 0.28 11.2 10.9 3.1 2 1 1 3 3 2 0 Prefoldin subunit Tektin PF03148.14 OAJ30703.1 - 0.072 11.8 20.9 1.5 7.5 15.8 2.4 1 1 1 2 2 2 0 Tektin family Phage_GP20 PF06810.11 OAJ30703.1 - 0.1 12.4 17.3 0.13 12.1 4.8 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 HALZ PF02183.18 OAJ30703.1 - 0.38 11.0 8.5 0.34 11.1 2.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 OAJ30703.1 - 0.44 11.0 25.5 0.17 12.4 5.9 3.8 2 1 3 5 5 4 0 Cell division protein ZapB DUF4407 PF14362.6 OAJ30703.1 - 0.49 9.7 9.9 0.17 11.2 4.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 OAJ30703.1 - 0.54 10.5 12.1 0.69 10.2 1.0 3.1 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 OAJ30703.1 - 0.58 10.3 9.8 0.45 10.6 2.8 3.4 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.12 OAJ30703.1 - 0.78 10.2 4.9 5.2 7.6 0.8 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein FPP PF05911.11 OAJ30703.1 - 0.79 7.8 25.6 3.1 5.9 4.6 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fmp27_WPPW PF10359.9 OAJ30703.1 - 0.97 8.2 15.5 1.4 7.7 0.5 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Baculo_PEP_C PF04513.12 OAJ30703.1 - 1 9.4 6.2 0.46 10.5 1.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 OAJ30703.1 - 1.1 9.0 20.5 0.78 9.5 17.2 2.3 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Bacillus_HBL PF05791.11 OAJ30703.1 - 1.3 8.8 7.4 0.23 11.3 3.5 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.11 OAJ30703.1 - 1.3 9.4 16.1 8.3 6.9 0.7 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.9 OAJ30703.1 - 1.5 8.3 22.4 3 7.2 12.5 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 ADIP PF11559.8 OAJ30703.1 - 1.5 8.9 19.7 0.32 11.1 10.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 OAJ30703.1 - 1.6 8.1 23.6 4.5 6.7 23.8 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 OAJ30703.1 - 1.9 9.5 27.6 0.049 14.5 12.5 2.8 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 OAJ30703.1 - 2 6.2 11.5 3.3 5.5 11.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 OAJ30703.1 - 2.4 6.9 23.2 0.36 9.6 13.3 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2115 PF09888.9 OAJ30703.1 - 2.4 8.6 5.3 3.2 8.3 4.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) RasGAP_C PF03836.15 OAJ30703.1 - 3.8 7.7 11.4 43 4.3 7.8 3.0 1 1 0 2 2 2 0 RasGAP C-terminus Syntaxin-6_N PF09177.11 OAJ30703.1 - 5 7.7 21.8 4.1 8.0 4.9 3.7 2 1 2 4 4 3 0 Syntaxin 6, N-terminal Prominin PF05478.11 OAJ30703.1 - 5.3 4.9 7.3 8.9 4.1 7.3 1.3 1 0 0 1 1 1 0 Prominin SKA1 PF07160.12 OAJ30703.1 - 5.6 6.7 13.6 1.5 8.6 8.0 2.2 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CENP-H PF05837.12 OAJ30703.1 - 6 7.3 21.8 2.8 8.4 4.0 3.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 OAJ30703.1 - 7 6.8 16.6 0.52 10.4 0.6 4.3 3 1 2 5 5 4 0 TolA binding protein trimerisation COG2 PF06148.11 OAJ30703.1 - 7.8 6.6 13.6 0.66 10.1 2.4 3.0 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 OAJ30703.1 - 7.9 5.5 14.5 11 5.0 8.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 OAJ30703.1 - 8 7.3 13.3 16 6.3 2.6 3.4 2 1 2 4 4 4 0 Occludin homology domain bZIP_1 PF00170.21 OAJ30703.1 - 8.3 6.6 19.0 1.5 9.0 1.5 4.0 3 1 1 4 4 4 0 bZIP transcription factor Cnn_1N PF07989.11 OAJ30703.1 - 9.1 6.5 15.8 22 5.3 0.9 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 FMN_dh PF01070.18 OAJ30704.1 - 1.4e-101 340.0 0.2 4.3e-91 305.5 0.1 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.17 OAJ30704.1 - 4e-05 22.9 0.1 6.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 OAJ30704.1 - 0.00025 20.2 2.2 0.00046 19.3 2.0 1.5 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 OAJ30704.1 - 0.0089 15.4 0.7 1.9 7.7 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG TGT PF01702.18 OAJ30704.1 - 0.26 10.4 0.1 6.8 5.7 0.0 2.2 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase UreF PF01730.16 OAJ30705.1 - 5e-18 66.0 3.3 1e-17 65.0 3.3 1.5 1 0 0 1 1 1 1 UreF Peptidase_M20 PF01546.28 OAJ30706.1 - 1.2e-24 87.2 0.0 2.8e-24 86.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 OAJ30706.1 - 3.5e-11 43.0 1.7 1.8e-10 40.7 1.7 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3152 PF11350.8 OAJ30706.1 - 0.036 13.7 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) BST2 PF16716.5 OAJ30706.1 - 0.14 12.8 1.1 0.29 11.7 1.1 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF3953 PF13129.6 OAJ30706.1 - 2.2 8.1 3.3 4.4 7.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3953) ADH_N PF08240.12 OAJ30707.1 - 5.3e-25 87.4 3.6 5.3e-25 87.4 3.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ30707.1 - 1.1e-13 51.3 0.2 1.8e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ30707.1 - 0.00052 19.4 0.1 0.0013 18.2 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 OAJ30707.1 - 0.0057 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 OAJ30707.1 - 0.017 14.4 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Oxidored_nitro PF00148.19 OAJ30707.1 - 0.019 13.7 0.1 0.045 12.5 0.0 1.6 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase NAD_binding_2 PF03446.15 OAJ30707.1 - 0.029 14.6 0.2 0.067 13.4 0.2 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 OAJ30707.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF983 PF06170.12 OAJ30707.1 - 0.33 11.4 1.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Pro_CA PF00484.19 OAJ30708.1 - 4.4e-38 131.0 0.0 6.5e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 OAJ30708.1 - 0.0065 16.1 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sda PF08970.10 OAJ30708.1 - 0.16 11.7 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A XPG_N PF00752.17 OAJ30709.1 - 9.9e-35 119.1 0.0 1.8e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ30709.1 - 2.5e-31 107.9 0.0 5.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 OAJ30709.1 - 1.9e-07 31.6 0.0 5.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 OAJ30709.1 - 0.0026 18.3 0.1 0.012 16.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 OAJ30709.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif MFS_1 PF07690.16 OAJ30710.1 - 6.2e-41 140.5 45.7 1.3e-40 139.4 43.1 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ30710.1 - 4.4e-17 61.7 10.6 4.4e-17 61.7 10.6 1.7 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 OAJ30710.1 - 1.5e-12 47.2 13.0 1.5e-12 47.2 13.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter bZIP_2 PF07716.15 OAJ30711.1 - 1.4e-08 34.7 12.4 1.4e-08 34.7 12.4 3.1 2 1 0 2 2 1 1 Basic region leucine zipper TFIIA PF03153.13 OAJ30711.1 - 2.5e-05 24.4 40.2 2.5e-05 24.4 40.2 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 OAJ30711.1 - 0.00085 19.6 7.0 0.00085 19.6 7.0 1.8 2 0 0 2 2 2 1 DDHD domain Velvet PF11754.8 OAJ30711.1 - 0.0047 16.9 12.1 0.011 15.7 12.1 1.6 1 0 0 1 1 1 1 Velvet factor CLN3 PF02487.17 OAJ30711.1 - 0.015 14.4 8.7 0.025 13.7 8.7 1.2 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 OAJ30711.1 - 0.016 13.5 32.5 0.024 12.9 32.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.9 OAJ30711.1 - 0.018 15.4 15.0 0.051 14.0 15.0 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like ABC2_membrane_2 PF12679.7 OAJ30711.1 - 0.056 12.7 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 OAJ30711.1 - 0.061 12.5 4.8 0.1 11.8 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 OAJ30711.1 - 0.8 6.7 20.4 1.1 6.3 20.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 OAJ30711.1 - 1.2 7.9 21.8 2.1 7.1 21.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Endostatin PF06482.11 OAJ30711.1 - 1.4 8.3 20.5 2.9 7.3 20.5 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 OAJ30711.1 - 1.6 7.7 20.7 3.1 6.7 20.7 1.4 1 0 0 1 1 1 0 Solute carrier family 12 YabA PF06156.13 OAJ30711.1 - 2 9.1 0.0 2 9.1 0.0 2.4 2 0 0 2 2 1 0 Initiation control protein YabA SpoIIP PF07454.11 OAJ30711.1 - 2.9 7.3 22.6 5.9 6.3 22.6 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DcuA_DcuB PF03605.14 OAJ30711.1 - 3.3 6.5 4.7 5.4 5.8 4.7 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF913 PF06025.12 OAJ30711.1 - 4.2 6.2 12.3 7.4 5.4 12.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.6 OAJ30711.1 - 5.7 5.2 9.6 8.2 4.7 9.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 OAJ30711.1 - 8.5 5.7 12.4 0.49 9.8 7.0 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MFS_1 PF07690.16 OAJ30712.1 - 3.2e-17 62.5 31.1 3.2e-17 62.5 31.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 OAJ30712.1 - 1.5e-14 54.0 7.2 1.5e-14 54.0 7.2 2.8 4 1 0 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 OAJ30712.1 - 0.09 11.6 12.4 0.0085 15.0 6.2 2.3 1 1 2 3 3 3 0 MFS_1 like family RTP1_C1 PF10363.9 OAJ30713.1 - 1.7e-32 111.9 0.0 9.5e-32 109.5 0.0 2.3 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 OAJ30713.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 TPR_17 PF13431.6 OAJ30714.1 - 5.3e-06 26.4 0.5 0.24 11.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ30714.1 - 0.00019 21.3 15.0 0.19 12.0 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ30714.1 - 0.0027 17.5 0.9 2.9 7.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ30714.1 - 0.019 15.5 0.1 22 5.6 0.0 4.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ30714.1 - 0.022 14.9 0.0 23 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ30714.1 - 0.048 14.5 10.7 0.17 12.8 0.2 6.2 5 2 1 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ30714.1 - 0.11 12.7 1.3 0.39 11.0 0.7 2.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 OAJ30714.1 - 0.74 10.1 12.4 1.8 8.9 0.2 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ30714.1 - 8.4 6.6 9.1 19 5.5 0.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Proteasome PF00227.26 OAJ30715.1 - 2e-33 115.5 0.0 2.4e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Bromodomain PF00439.25 OAJ30717.1 - 2.5e-17 62.7 0.1 6.3e-17 61.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain Peptidase_M1 PF01433.20 OAJ30717.1 - 7.7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 OAJ30717.1 - 0.00016 22.0 1.4 0.29 11.5 0.1 3.7 3 0 0 3 3 3 2 HEAT repeats Peptidase_M1_N PF17900.1 OAJ30717.1 - 0.034 14.3 0.5 2.5 8.3 0.0 2.7 3 0 0 3 3 3 0 Peptidase M1 N-terminal domain Glyco_hydro_31 PF01055.26 OAJ30718.1 - 2.9e-131 438.7 1.3 3.7e-131 438.3 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 OAJ30718.1 - 1.1e-22 80.1 0.2 2.9e-21 75.5 0.0 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 OAJ30718.1 - 0.00076 19.7 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) 2OG-FeII_Oxy PF03171.20 OAJ30719.1 - 1.7e-11 44.5 0.1 1.3e-10 41.7 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 OAJ30719.1 - 1.5e-10 41.9 0.2 3.1e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal RasGEF PF00617.19 OAJ30720.1 - 1.2e-57 195.0 0.1 1.8e-57 194.4 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ30720.1 - 4.2e-26 91.2 0.1 8.9e-26 90.2 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif PIF1 PF05970.14 OAJ30722.1 - 1.7e-104 349.9 0.0 2.2e-104 349.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ30722.1 - 3e-55 187.4 0.2 7.2e-55 186.2 0.2 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ30722.1 - 4.7e-10 39.5 0.1 9.2e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ30722.1 - 2.3e-05 22.5 0.0 4.9e-05 21.5 0.0 1.4 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 OAJ30722.1 - 0.0032 17.8 0.0 0.025 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 OAJ30722.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Zeta_toxin PF06414.12 OAJ30722.1 - 0.036 13.3 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 OAJ30722.1 - 0.1 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 OAJ30722.1 - 0.2 11.7 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RVT_1 PF00078.27 OAJ30724.1 - 2e-14 53.6 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnd2 PF05786.14 OAJ30728.1 - 1.7e-156 523.1 0.1 1.7e-156 523.1 0.1 5.0 2 1 1 3 3 3 1 Condensin complex subunit 2 DUF4152 PF13680.6 OAJ30728.1 - 2e-05 24.1 0.1 3.6e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4152) CNDH2_N PF06278.11 OAJ30728.1 - 0.11 12.8 1.4 0.95 9.7 0.0 2.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal GCFC PF07842.12 OAJ30729.1 - 2.4e-66 224.2 14.1 3.3e-66 223.7 14.1 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 OAJ30729.1 - 8.5e-08 32.0 0.2 8.5e-08 32.0 0.2 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 OAJ30729.1 - 0.00081 19.4 0.3 0.00081 19.4 0.3 3.6 3 1 1 4 4 4 1 G-patch domain Birna_VP4 PF01768.16 OAJ30730.1 - 0.26 11.0 2.0 0.18 11.6 0.4 1.5 2 0 0 2 2 2 0 Birnavirus VP4 protein TatD_DNase PF01026.21 OAJ30731.1 - 1e-49 169.3 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase His_Phos_1 PF00300.22 OAJ30732.1 - 2.5e-17 63.2 0.7 1.1e-09 38.3 0.3 4.4 3 1 1 4 4 4 4 Histidine phosphatase superfamily (branch 1) Fer2_4 PF13510.6 OAJ30733.1 - 9.8e-20 70.4 0.1 2.4e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 OAJ30733.1 - 1.3e-15 56.6 0.1 1.3e-15 56.6 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 OAJ30733.1 - 5.1e-09 36.0 1.2 1.5e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 OAJ30733.1 - 0.027 14.3 1.4 2.1 8.3 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 OAJ30733.1 - 0.045 13.8 0.2 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster NDUF_B8 PF05821.11 OAJ30734.1 - 3.2e-09 36.9 0.2 9.8e-09 35.3 0.2 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF4380 PF14315.6 OAJ30734.1 - 0.027 13.4 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) SR-25 PF10500.9 OAJ30734.1 - 2.5 7.7 6.1 3.5 7.2 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein XPG_N PF00752.17 OAJ30735.1 - 1e-28 99.7 0.0 2e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 OAJ30735.1 - 3.8e-27 94.5 0.0 1.1e-26 93.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region HHH_5 PF14520.6 OAJ30735.1 - 0.092 13.4 0.0 0.58 10.8 0.0 2.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain PLA2_B PF01735.18 OAJ30738.1 - 1.3e-136 455.9 1.6 1.5e-136 455.7 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 OAJ30738.1 - 3.1e-05 24.2 1.9 0.00013 22.2 1.9 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Metallophos PF00149.28 OAJ30739.1 - 2.1e-36 126.3 0.5 3e-36 125.8 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 OAJ30739.1 - 0.0017 18.8 0.1 0.0033 17.8 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 OAJ30739.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RPE65 PF03055.15 OAJ30740.1 - 4.7e-96 322.8 0.0 1e-95 321.7 0.0 1.5 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein Eisosome1 PF12757.7 OAJ30740.1 - 0.028 14.7 1.9 0.049 13.9 1.9 1.3 1 0 0 1 1 1 0 Eisosome protein 1 Syja_N PF02383.18 OAJ30741.1 - 2.5e-78 263.6 0.0 3.7e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Pil1 PF13805.6 OAJ30743.1 - 7.8e-13 48.5 2.5 2.1e-12 47.1 2.5 1.7 1 0 0 1 1 1 1 Eisosome component PIL1 FHA PF00498.26 OAJ30744.1 - 5.3e-07 29.9 0.0 5.3e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 FHA domain Gti1_Pac2 PF09729.9 OAJ30745.1 - 2e-56 190.9 0.0 5.5e-56 189.5 0.0 1.8 1 0 0 1 1 1 1 Gti1/Pac2 family AMP-binding PF00501.28 OAJ30746.1 - 2.4e-77 260.3 0.0 3.1e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ30746.1 - 1.4e-12 48.4 0.2 1.1e-11 45.6 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 OAJ30747.1 - 7.1e-84 281.8 0.0 9.5e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ30747.1 - 2.2e-10 41.4 0.0 8.7e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tubulin PF00091.25 OAJ30748.1 - 1.1e-71 241.2 0.0 3e-71 239.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ30748.1 - 3e-42 143.8 0.3 4.6e-42 143.1 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ30748.1 - 6.6e-07 29.7 0.1 1.8e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ30748.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 OAJ30748.1 - 0.0022 17.2 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Pirin PF02678.16 OAJ30749.1 - 6e-28 97.0 0.9 9.3e-28 96.4 0.9 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 OAJ30749.1 - 1.7e-06 27.6 1.6 1.6e-05 24.5 0.5 2.4 2 0 0 2 2 2 1 Cupin domain DUF3337 PF11816.8 OAJ30750.1 - 7.5e-34 117.1 0.0 1.3e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 OAJ30750.1 - 1.8e-20 72.9 22.2 1.3e-05 25.9 0.1 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ30750.1 - 9.9e-06 25.8 0.0 0.019 15.3 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ30750.1 - 0.26 10.2 0.0 0.59 9.0 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ketoacyl-synt_C PF02801.22 OAJ30752.1 - 0.05 13.6 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain Ins_P5_2-kin PF06090.12 OAJ30753.1 - 9.1e-63 212.7 0.0 1.2e-62 212.3 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase zf-C2H2 PF00096.26 OAJ30753.1 - 1.6e-11 44.0 7.4 2.3e-05 24.6 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ30753.1 - 1.2e-05 25.7 6.6 0.04 14.8 2.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 OAJ30753.1 - 0.02 15.3 10.2 0.02 15.3 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain DUF3268 PF11672.8 OAJ30753.1 - 0.096 13.0 0.5 0.2 12.0 0.5 1.5 1 0 0 1 1 1 0 zinc-finger-containing domain zf-C2H2_11 PF16622.5 OAJ30753.1 - 0.36 10.6 3.1 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 OAJ30753.1 - 0.59 10.1 3.9 14 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 OAJ30753.1 - 1.4 9.0 4.1 6.3 6.9 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2235 PF09994.9 OAJ30755.1 - 3.5e-70 236.6 0.0 5.2e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TauD PF02668.16 OAJ30756.1 - 3.6e-27 95.8 0.0 6e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_4 PF01565.23 OAJ30757.1 - 2.3e-22 79.3 3.0 5.2e-22 78.1 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 OAJ30757.1 - 0.012 15.7 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like DCP2 PF05026.13 OAJ30758.1 - 6.1e-24 84.2 0.1 1.1e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 OAJ30758.1 - 2.2e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-HIT PF04438.16 OAJ30759.1 - 1.9e-08 34.0 9.2 3.1e-08 33.3 9.2 1.3 1 0 0 1 1 1 1 HIT zinc finger ORC5_C PF14630.6 OAJ30760.1 - 3.6e-49 167.8 0.2 8.8e-49 166.5 0.2 1.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 OAJ30760.1 - 0.00058 20.3 2.8 0.00096 19.6 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF2012 PF09430.10 OAJ30761.1 - 5.1e-21 75.0 0.0 1.3e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) DUF5516 PF17637.2 OAJ30762.1 - 0.037 13.8 0.2 0.061 13.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5516) DUF4089 PF13318.6 OAJ30762.1 - 1.1 9.8 5.8 2 8.9 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4089) Thioesterase PF00975.20 OAJ30763.1 - 8.5e-08 32.6 0.1 1.9e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Iwr1 PF08574.10 OAJ30764.1 - 0.0022 19.0 12.8 0.0022 19.0 12.8 3.8 2 1 1 3 3 3 1 Transcription factor Iwr1 Cnd1 PF12717.7 OAJ30766.1 - 1.5e-54 184.4 2.3 1.2e-47 161.9 0.1 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 OAJ30766.1 - 6.5e-37 126.9 0.0 6.5e-37 126.9 0.0 4.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term Adaptin_N PF01602.20 OAJ30766.1 - 1.5e-08 33.7 1.9 0.013 14.1 0.1 4.6 4 2 1 5 5 5 4 Adaptin N terminal region HEAT PF02985.22 OAJ30766.1 - 1.1e-06 28.4 0.7 0.82 10.1 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 OAJ30766.1 - 4.1e-06 27.1 1.3 0.45 10.9 0.0 4.7 5 0 0 5 5 5 2 HEAT repeats Cnd3 PF12719.7 OAJ30766.1 - 8.8e-06 25.1 1.0 0.00021 20.6 0.3 2.8 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OAJ30766.1 - 0.00016 21.8 0.5 0.44 10.7 0.1 3.8 2 2 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 OAJ30766.1 - 0.065 13.8 6.2 1.9 9.1 0.0 4.5 4 0 0 4 4 4 0 HEAT-like repeat XAP5 PF04921.14 OAJ30766.1 - 6.2 6.6 11.0 18 5.0 11.0 1.7 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 OAJ30766.1 - 7.2 4.8 23.3 0.023 13.0 13.7 1.5 2 0 0 2 2 2 0 CDC45-like protein FAD_binding_2 PF00890.24 OAJ30767.1 - 1.1e-32 113.6 0.0 1.8e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 OAJ30767.1 - 1.7e-22 79.4 0.2 5e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Chorion_2 PF03964.15 OAJ30767.1 - 1.4 9.8 5.0 2.8 8.8 3.5 2.0 1 1 1 2 2 2 0 Chorion family 2 Rgp1 PF08737.10 OAJ30768.1 - 3.3e-83 280.2 0.0 7.9e-83 278.9 0.0 1.7 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 OAJ30768.1 - 1.2e-06 28.7 0.1 0.1 12.7 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 OAJ30768.1 - 0.048 13.2 0.0 9.5 5.7 0.0 2.3 2 0 0 2 2 2 0 SpoOM protein DPBB_1 PF03330.18 OAJ30769.1 - 0.00019 21.7 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase KH_6 PF15985.5 OAJ30770.1 - 2.5e-08 34.2 0.0 4.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 OAJ30770.1 - 3.3e-07 30.0 0.2 6.6e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RFC1 PF08519.12 OAJ30771.1 - 7.4e-51 172.4 0.1 2.8e-50 170.5 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 OAJ30771.1 - 2.9e-11 43.6 0.0 8.6e-11 42.1 0.0 1.9 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 OAJ30771.1 - 1.6e-09 38.3 0.0 4.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ30771.1 - 1e-06 28.8 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 OAJ30771.1 - 0.0017 18.8 0.0 0.005 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ30771.1 - 0.0024 18.1 0.0 0.0058 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ30771.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 OAJ30771.1 - 0.0029 17.4 0.2 0.046 13.5 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 OAJ30771.1 - 0.0035 17.1 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ30771.1 - 0.0039 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ30771.1 - 0.012 15.4 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 OAJ30771.1 - 0.02 15.2 0.0 0.084 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain AAA_33 PF13671.6 OAJ30771.1 - 0.028 14.6 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 OAJ30771.1 - 0.069 13.0 0.5 0.22 11.4 0.1 2.0 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.6 OAJ30771.1 - 0.075 13.3 0.2 0.77 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 OAJ30771.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 OAJ30771.1 - 0.13 12.2 0.0 0.78 9.6 0.0 2.2 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 OAJ30771.1 - 0.13 12.7 1.4 3.5 8.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 OAJ30771.1 - 0.17 12.4 0.5 9.2 6.8 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_11 PF13086.6 OAJ30771.1 - 1.2 8.9 5.9 1.1 8.9 0.3 2.3 1 1 1 2 2 2 0 AAA domain Sec7 PF01369.20 OAJ30773.1 - 8.2e-71 237.5 0.1 1.7e-70 236.4 0.1 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 OAJ30773.1 - 5.7e-45 153.0 5.3 5.7e-45 153.0 5.3 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 OAJ30773.1 - 1.5e-26 92.0 1.4 4.6e-25 87.3 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DCB PF16213.5 OAJ30773.1 - 2e-20 73.2 4.8 7.4e-20 71.3 0.1 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Spt20 PF12090.8 OAJ30773.1 - 0.11 12.1 14.1 0.24 11.0 14.1 1.5 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 OAJ30773.1 - 1.2 9.0 22.7 3.1 7.7 22.7 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hydin_ADK PF17213.3 OAJ30773.1 - 2 8.7 6.2 5 7.3 6.2 1.7 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain GDI PF00996.18 OAJ30774.1 - 1.4e-29 103.0 0.0 7.1e-18 64.3 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_8 PF05148.15 OAJ30775.1 - 6.6e-52 176.5 0.0 8.2e-26 91.2 0.0 3.1 3 0 0 3 3 3 2 Hypothetical methyltransferase Methyltransf_25 PF13649.6 OAJ30775.1 - 0.0032 18.1 0.1 2.1 9.1 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain MTS PF05175.14 OAJ30775.1 - 0.005 16.4 0.1 0.8 9.2 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 OAJ30775.1 - 0.023 14.5 0.0 0.68 9.7 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ30775.1 - 0.029 15.0 0.0 0.75 10.5 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain GREB1 PF15782.5 OAJ30775.1 - 4.7 4.2 11.5 6.9 3.6 11.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3140 PF11338.8 OAJ30776.1 - 4.1e-34 116.9 1.6 4.9e-34 116.6 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 OAJ30776.1 - 0.023 15.2 0.1 0.038 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Lipoprotein_Ltp PF07553.11 OAJ30776.1 - 0.031 14.5 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein DUF3673 PF12425.8 OAJ30776.1 - 0.085 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) Rot1 PF10681.9 OAJ30777.1 - 2.7e-47 161.0 1.1 3.3e-47 160.7 1.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal BsuPI PF12690.7 OAJ30777.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Intracellular proteinase inhibitor VMA21 PF09446.10 OAJ30778.1 - 1.4e-12 47.6 9.8 2e-12 47.0 9.8 1.3 1 0 0 1 1 1 1 VMA21-like domain DnaJ PF00226.31 OAJ30780.1 - 1.6e-15 56.9 0.3 2.8e-15 56.2 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Kinesin PF00225.23 OAJ30781.1 - 2.3e-110 368.6 0.0 3.3e-110 368.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ30781.1 - 6.5e-24 84.6 0.0 1.3e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding GPS2_interact PF15784.5 OAJ30781.1 - 0.08 13.4 0.8 0.24 11.9 0.2 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Myosin_tail_1 PF01576.19 OAJ30781.1 - 0.094 10.5 4.9 0.14 9.9 4.9 1.1 1 0 0 1 1 1 0 Myosin tail MSL1_dimer PF16801.5 OAJ30781.1 - 0.23 11.3 2.9 0.44 10.4 2.9 1.4 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Seryl_tRNA_N PF02403.22 OAJ30781.1 - 0.81 9.9 6.4 0.93 9.8 3.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 OAJ30781.1 - 4 7.8 5.4 33 4.8 0.6 2.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain Y_phosphatase2 PF03162.13 OAJ30782.1 - 9.7e-46 155.4 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Pex2_Pex12 PF04757.14 OAJ30782.1 - 6.5e-35 120.7 3.7 1e-34 120.1 3.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Y_phosphatase3 PF13350.6 OAJ30782.1 - 9.1e-06 25.8 0.0 1.7e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myc_N PF01056.18 OAJ30782.1 - 0.37 10.6 2.5 14 5.5 0.3 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF5421 PF17458.2 OAJ30782.1 - 3.1 7.1 6.1 0.3 10.4 1.7 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5421) TRP PF06011.12 OAJ30783.1 - 3.8e-28 98.4 17.0 1.2e-20 73.7 15.2 2.4 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel PGA2 PF07543.12 OAJ30784.1 - 1 9.3 6.4 0.48 10.4 1.9 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Iwr1 PF08574.10 OAJ30784.1 - 1.9 9.5 8.5 1.3 10.1 6.5 1.9 2 0 0 2 2 2 0 Transcription factor Iwr1 FAD_binding_3 PF01494.19 OAJ30785.1 - 3.1e-55 187.8 0.3 1.3e-54 185.8 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 OAJ30785.1 - 3.2e-18 66.3 0.0 5.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 OAJ30785.1 - 6.3e-06 26.3 0.0 1.6e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ30785.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ30785.1 - 0.00017 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ30785.1 - 0.00028 19.7 0.1 0.00043 19.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 OAJ30785.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 OAJ30785.1 - 0.0025 16.9 0.3 0.0039 16.3 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 OAJ30785.1 - 0.0028 16.6 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 OAJ30785.1 - 0.004 16.3 0.5 0.004 16.3 0.5 1.8 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ30785.1 - 0.0042 17.6 0.1 0.01 16.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ30785.1 - 0.013 14.7 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ30785.1 - 0.038 14.0 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ30785.1 - 0.076 13.3 0.1 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 OAJ30785.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 OAJ30785.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FANC_SAP PF18081.1 OAJ30786.1 - 0.1 12.8 0.5 0.4 10.9 0.5 2.1 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain TetR_C_15 PF17918.1 OAJ30786.1 - 0.61 10.9 0.0 0.61 10.9 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain AA_permease PF00324.21 OAJ30787.1 - 1.5e-127 426.1 37.1 1.8e-127 425.8 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 OAJ30787.1 - 2.2e-39 135.5 41.4 2.7e-39 135.2 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease TPP_enzyme_N PF02776.18 OAJ30788.1 - 3e-33 114.9 0.1 4.4e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 OAJ30788.1 - 4.7e-23 81.4 0.0 9.8e-22 77.2 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 OAJ30788.1 - 8.4e-16 58.1 0.2 1.5e-14 54.0 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cutinase PF01083.22 OAJ30789.1 - 8.4e-08 32.4 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase Pkinase PF00069.25 OAJ30790.1 - 1.1e-62 211.9 0.0 1.6e-61 208.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30790.1 - 3.5e-26 92.0 0.0 6.9e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ30790.1 - 2.1e-07 30.2 0.0 4.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 OAJ30790.1 - 0.0044 16.4 0.0 0.015 14.6 0.0 1.9 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ30790.1 - 0.066 12.0 0.0 0.066 12.0 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase Kinase-like PF14531.6 OAJ30790.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.5 3 0 0 3 3 3 0 Kinase-like APH PF01636.23 OAJ30790.1 - 0.1 12.5 0.1 0.1 12.5 0.1 4.1 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ30790.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 OAJ30790.1 - 0.21 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3000 PF11452.8 OAJ30790.1 - 0.22 11.0 1.5 0.49 9.9 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) zf-C2H2_4 PF13894.6 OAJ30791.1 - 1.2e-05 25.8 6.7 0.056 14.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ30791.1 - 0.00013 22.2 12.3 0.0019 18.5 0.8 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 OAJ30791.1 - 0.053 13.5 0.9 0.12 12.4 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 OAJ30791.1 - 0.63 10.5 4.2 0.34 11.4 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ETC_C1_NDUFA5 PF04716.14 OAJ30792.1 - 1.2e-21 76.2 0.2 1.7e-21 75.8 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Prefoldin_2 PF01920.20 OAJ30792.1 - 0.00046 20.1 0.5 0.00067 19.6 0.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Abhydrolase_1 PF00561.20 OAJ30793.1 - 1.7e-18 67.2 0.3 6e-07 29.4 0.1 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ30793.1 - 8e-15 56.0 2.1 1.5e-14 55.2 2.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ30793.1 - 0.00024 20.5 0.1 0.001 18.4 0.3 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 EHN PF06441.12 OAJ30793.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Glyoxalase PF00903.25 OAJ30794.1 - 8.9e-05 22.7 0.0 0.0004 20.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 OAJ30794.1 - 0.12 12.4 0.0 5.8 6.9 0.0 2.5 3 0 0 3 3 3 0 Glyoxalase-like domain Ribophorin_II PF05817.14 OAJ30795.1 - 6e-10 38.3 1.3 4.1e-07 28.9 1.0 2.0 2 0 0 2 2 2 2 Oligosaccharyltransferase subunit Ribophorin II HAT_KAT11 PF08214.11 OAJ30796.1 - 0.24 10.6 0.5 0.38 10.0 0.5 1.2 1 0 0 1 1 1 0 Histone acetylation protein RIC1 PF07064.13 OAJ30798.1 - 1.2e-91 306.7 0.0 1.6e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 OAJ30798.1 - 0.0017 18.6 0.1 0.41 11.0 0.1 4.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Formyl_trans_N PF00551.19 OAJ30799.1 - 0.011 15.5 0.2 0.013 15.2 0.2 1.1 1 0 0 1 1 1 0 Formyl transferase Amidohydro_2 PF04909.14 OAJ30800.1 - 0.00054 19.8 0.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase DUF1754 PF08555.10 OAJ30800.1 - 0.25 12.2 2.4 0.6 10.9 2.4 1.5 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) TBCA PF02970.16 OAJ30801.1 - 2.6e-27 95.0 5.1 2.6e-27 95.0 5.1 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor A TaqI_C PF12950.7 OAJ30801.1 - 0.11 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain eIF-4B PF06273.11 OAJ30801.1 - 0.13 11.3 4.5 0.14 11.2 4.5 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Phage_Gp23 PF10669.9 OAJ30801.1 - 0.21 11.9 8.3 0.046 14.1 5.1 1.5 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Atg14 PF10186.9 OAJ30801.1 - 4.6 6.2 10.0 5 6.1 10.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 OAJ30801.1 - 6.6 6.0 10.7 7.6 5.8 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RHD3 PF05879.12 OAJ30802.1 - 5.2e-247 821.7 0.0 6.5e-247 821.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 OAJ30802.1 - 2e-05 24.6 0.0 5.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 OAJ30802.1 - 2.6e-05 24.4 0.3 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GBP PF02263.19 OAJ30802.1 - 5.9e-05 22.5 0.2 0.00012 21.4 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 OAJ30802.1 - 0.009 16.3 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF4259 PF14078.6 OAJ30802.1 - 0.047 14.4 0.4 0.11 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) AAA_16 PF13191.6 OAJ30802.1 - 0.15 12.4 2.1 1.3 9.3 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain HAT_KAT11 PF08214.11 OAJ30803.1 - 2.2e-26 93.0 0.1 3.2e-14 53.0 0.0 4.4 3 2 0 3 3 3 2 Histone acetylation protein zf-PARP PF00645.18 OAJ30803.1 - 8.7e-20 71.4 0.0 2.6e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 OAJ30803.1 - 0.043 13.7 1.6 0.21 11.6 1.6 2.3 1 0 0 1 1 1 0 AT hook motif Rad52_Rad22 PF04098.15 OAJ30804.1 - 7.7e-56 188.3 0.0 1.2e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF21 PF01595.20 OAJ30805.1 - 5.5e-37 127.2 0.3 5.5e-37 127.2 0.3 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ30805.1 - 0.023 15.1 1.5 7.1 7.2 0.1 3.5 3 0 0 3 3 3 0 CBS domain Sec2p PF06428.11 OAJ30806.1 - 9.2e-18 64.0 8.8 2.4e-17 62.7 8.8 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Roughex PF06020.11 OAJ30806.1 - 0.19 10.8 9.4 0.39 9.8 9.4 1.5 1 0 0 1 1 1 0 Drosophila roughex protein SlyX PF04102.12 OAJ30806.1 - 2.2 8.9 7.5 4 8.1 0.2 3.4 2 1 0 3 3 3 0 SlyX Lyase_aromatic PF00221.19 OAJ30807.1 - 3.6e-120 401.8 3.2 5.2e-120 401.2 3.2 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase Nitroreductase PF00881.24 OAJ30807.1 - 0.03 14.4 0.1 0.085 12.9 0.1 1.7 1 0 0 1 1 1 0 Nitroreductase family MFS_1 PF07690.16 OAJ30808.1 - 3e-33 115.2 34.2 2.6e-31 108.8 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ30808.1 - 6.5e-10 38.5 14.9 1.7e-09 37.1 14.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 OAJ30808.1 - 2.7e-06 26.1 4.8 5.8e-06 25.0 3.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UL42 PF17638.2 OAJ30808.1 - 0.32 11.0 2.8 0.25 11.3 0.2 2.1 3 0 0 3 3 3 0 HCMV UL42 Transp_cyt_pur PF02133.15 OAJ30809.1 - 4.2e-19 68.6 30.7 5.6e-19 68.2 30.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin OrfB_Zn_ribbon PF07282.11 OAJ30810.1 - 3.4e-13 49.3 0.3 5.9e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain OrfB_IS605 PF01385.19 OAJ30810.1 - 0.00035 20.8 0.5 0.00076 19.7 0.2 1.7 1 1 1 2 2 2 1 Probable transposase zf-TFIIB PF13453.6 OAJ30810.1 - 0.27 10.6 1.3 0.85 9.0 1.4 1.8 1 1 0 1 1 1 0 Transcription factor zinc-finger ADH_N PF08240.12 OAJ30811.1 - 2e-25 88.8 0.6 3.7e-25 87.9 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ30811.1 - 5.1e-21 75.0 0.0 1.1e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ30811.1 - 2.9e-08 33.4 0.1 0.0093 15.5 0.0 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 OAJ30811.1 - 0.0045 16.3 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 OAJ30811.1 - 0.0059 17.7 0.0 0.017 16.2 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 OAJ30811.1 - 0.0077 15.6 0.4 0.014 14.7 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 OAJ30811.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 OAJ30811.1 - 0.034 12.9 0.2 0.047 12.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 OAJ30811.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ30811.1 - 0.36 11.4 1.8 0.55 10.8 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sad1_UNC PF07738.13 OAJ30812.1 - 1.8e-22 79.8 0.0 4.4e-10 39.7 0.0 3.7 2 2 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF1664 PF07889.12 OAJ30812.1 - 0.055 13.5 7.6 0.76 9.8 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 OAJ30812.1 - 0.32 10.3 17.7 0.042 13.2 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 OAJ30812.1 - 0.67 10.1 7.8 0.31 11.2 2.9 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 OAJ30812.1 - 0.79 9.2 32.8 0.92 9.0 11.2 4.2 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 OAJ30812.1 - 1.4 9.0 15.9 3.2 7.8 7.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 OAJ30812.1 - 1.7 7.1 11.3 3.8 6.0 11.3 1.5 1 0 0 1 1 1 0 AAA domain Cytochrom_B562 PF07361.11 OAJ30812.1 - 2 9.1 5.5 0.99 10.1 2.5 2.2 2 0 0 2 2 1 0 Cytochrome b562 Laminin_II PF06009.12 OAJ30812.1 - 2.4 8.2 14.5 1.6 8.8 5.7 2.8 1 1 1 2 2 2 0 Laminin Domain II LMBR1 PF04791.16 OAJ30812.1 - 3.4 6.5 5.1 5.1 5.9 5.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 OAJ30812.1 - 5 5.9 22.1 1.1 8.1 6.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 OAJ30812.1 - 5 7.2 10.6 6 6.9 0.4 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 OAJ30812.1 - 6.2 7.2 5.9 26 5.2 0.4 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein Filament PF00038.21 OAJ30812.1 - 9.7 5.7 23.0 2.2 7.8 3.4 2.8 2 1 0 3 3 3 0 Intermediate filament protein Aminotran_5 PF00266.19 OAJ30813.1 - 2.2e-07 30.2 0.0 3.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Pep1_7 PF17232.2 OAJ30813.1 - 0.019 15.4 0.0 8.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Elicitor peptide 1-7 DegT_DnrJ_EryC1 PF01041.17 OAJ30813.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TFIIA PF03153.13 OAJ30814.1 - 0.074 13.0 44.5 0.075 13.0 9.5 2.9 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 OAJ30814.1 - 2.3 8.2 10.9 8.8 6.3 0.6 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.13 OAJ30814.1 - 6.4 6.3 21.4 1.2 8.7 5.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) CopD PF05425.13 OAJ30815.1 - 0.021 15.2 4.2 0.84 10.1 0.3 2.5 2 1 0 2 2 2 0 Copper resistance protein D LapA_dom PF06305.11 OAJ30815.1 - 0.45 10.4 1.4 4.8 7.1 0.5 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tetraspanin PF00335.20 OAJ30815.1 - 1.3 8.7 5.1 0.16 11.6 0.8 1.6 2 0 0 2 2 2 0 Tetraspanin family Colicin_V PF02674.16 OAJ30815.1 - 5.8 6.9 7.9 0.23 11.4 1.0 2.1 2 1 0 2 2 2 0 Colicin V production protein PRIMA1 PF16101.5 OAJ30816.1 - 1 9.4 16.0 0.025 14.6 5.5 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FAD_binding_2 PF00890.24 OAJ30817.1 - 8.5e-48 163.4 0.5 1.1e-47 163.0 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 OAJ30817.1 - 0.0018 17.6 0.2 0.0025 17.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAJ30817.1 - 0.0069 15.6 0.2 0.012 14.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 OAJ30817.1 - 0.0091 15.3 0.2 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 OAJ30817.1 - 0.0095 15.1 2.0 0.014 14.5 2.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 OAJ30817.1 - 0.027 14.1 0.5 0.034 13.7 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ30817.1 - 0.1 11.3 0.5 0.17 10.6 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 OAJ30818.1 - 3.6e-54 184.4 0.0 5e-54 184.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 OAJ30818.1 - 1.1e-44 151.4 2.7 1.5e-44 151.0 2.7 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term AAA PF00004.29 OAJ30819.1 - 8.2e-15 55.4 0.0 1e-13 51.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ30819.1 - 7.9e-08 32.7 0.0 2.8e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ30819.1 - 1.7e-07 31.8 0.3 1.7e-07 31.8 0.3 3.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_lid_10 PF17872.1 OAJ30819.1 - 1.8e-06 28.0 0.8 1.8e-06 28.0 0.8 2.3 3 0 0 3 3 3 1 AAA lid domain AAA_19 PF13245.6 OAJ30819.1 - 0.011 16.1 0.0 0.011 16.1 0.0 3.1 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 OAJ30819.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 OAJ30819.1 - 0.54 10.0 0.0 0.54 10.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain SURF2 PF05477.11 OAJ30819.1 - 1.7 8.3 11.1 4.1 7.0 11.1 1.7 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 OAJ30819.1 - 5.7 5.1 12.2 9.4 4.4 12.2 1.4 1 0 0 1 1 1 0 CDC45-like protein SPT2 PF08243.11 OAJ30820.1 - 1.4e-13 51.3 28.5 1.4e-13 51.3 28.5 5.7 4 2 0 4 4 4 1 SPT2 chromatin protein F-box-like PF12937.7 OAJ30821.1 - 7.1e-05 22.6 0.1 0.00047 20.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like DUF2433 PF10360.9 OAJ30823.1 - 4.3e-45 152.8 0.1 7e-45 152.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 OAJ30823.1 - 0.076 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GTP_EFTU PF00009.27 OAJ30824.1 - 5.6e-33 114.1 0.0 2.7e-32 111.9 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 OAJ30824.1 - 9.1e-17 61.1 0.2 3e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 OAJ30824.1 - 9.3e-11 42.0 11.1 1.3e-09 38.3 0.2 4.0 3 1 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ30824.1 - 7.1e-07 29.3 0.1 3.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ30824.1 - 0.00024 21.3 0.0 0.00068 19.8 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 OAJ30824.1 - 0.0055 16.6 0.2 0.017 15.0 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 AAA_22 PF13401.6 OAJ30824.1 - 0.12 12.7 0.3 1 9.6 0.3 2.4 1 1 0 1 1 1 0 AAA domain PapB PF03333.13 OAJ30824.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein Trm112p PF03966.16 OAJ30825.1 - 8.6e-17 61.5 0.1 1.3e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zf-RING_7 PF02591.15 OAJ30825.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 C4-type zinc ribbon domain BST2 PF16716.5 OAJ30826.1 - 0.0023 18.5 4.3 0.023 15.2 0.0 2.8 2 1 0 2 2 2 1 Bone marrow stromal antigen 2 Myosin_tail_1 PF01576.19 OAJ30826.1 - 0.0058 14.5 14.6 0.06 11.2 15.3 1.8 1 1 1 2 2 2 2 Myosin tail ATG_C PF09333.11 OAJ30826.1 - 0.01 16.2 2.4 0.26 11.6 0.1 3.3 1 1 3 4 4 4 0 Autophagy-related protein C terminal domain Fzo_mitofusin PF04799.13 OAJ30826.1 - 0.012 15.2 0.4 0.024 14.2 0.4 1.4 1 1 0 1 1 1 0 fzo-like conserved region Laminin_II PF06009.12 OAJ30826.1 - 0.041 13.9 9.7 1 9.3 0.2 2.5 1 1 1 2 2 2 0 Laminin Domain II MAD PF05557.13 OAJ30826.1 - 0.052 11.9 4.6 0.066 11.6 4.6 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4407 PF14362.6 OAJ30826.1 - 0.33 10.3 11.6 0.55 9.5 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Orbi_NS1 PF01718.16 OAJ30826.1 - 0.37 9.2 0.8 0.47 8.9 0.8 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein ISG65-75 PF11727.8 OAJ30826.1 - 0.75 9.0 9.9 1.4 8.1 9.2 1.7 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF2968 PF11180.8 OAJ30826.1 - 1.9 8.1 9.8 0.21 11.2 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF2514 PF10721.9 OAJ30826.1 - 3.4 7.7 22.9 6.6 6.7 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2514) Sec2p PF06428.11 OAJ30826.1 - 5 7.2 12.4 2 8.4 6.3 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p EHN PF06441.12 OAJ30827.1 - 2.3e-24 85.8 0.0 4.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 OAJ30827.1 - 7.4e-10 38.9 0.1 1.3e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ30827.1 - 0.0013 19.4 5.2 0.0013 19.4 5.2 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Polysacc_deac_1 PF01522.21 OAJ30828.1 - 1.5e-21 76.6 0.0 4.3e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase DNA_ligase_A_N PF04675.14 OAJ30829.1 - 1.3e-19 71.2 0.0 1.8e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DUF4536 PF15055.6 OAJ30829.1 - 0.16 12.3 0.1 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) tRNA-synt_2b PF00587.25 OAJ30830.1 - 1.6e-07 31.5 0.0 2.1e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Abhydrolase_3 PF07859.13 OAJ30831.1 - 1.5e-29 103.4 0.0 4.3e-29 101.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 OAJ30831.1 - 0.00015 20.7 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 OAJ30831.1 - 0.11 12.0 0.0 8.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GYF PF02213.16 OAJ30832.1 - 6.9e-19 67.2 1.6 1.5e-18 66.2 1.6 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 OAJ30832.1 - 5.3e-06 26.1 0.2 1.4e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 GYF domain 2 DHHC PF01529.20 OAJ30833.1 - 1.1e-11 44.9 3.7 1.1e-11 44.9 3.7 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF3290 PF11694.8 OAJ30833.1 - 0.31 11.0 2.9 0.67 9.9 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) NDC10_II PF16787.5 OAJ30836.1 - 1.3e-60 205.1 0.0 1.8e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 OAJ30836.1 - 1.5e-17 63.6 0.5 3.1e-17 62.6 0.5 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MAP65_ASE1 PF03999.12 OAJ30836.1 - 0.072 11.8 0.1 0.14 10.8 0.1 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Aim19 PF10315.9 OAJ30837.1 - 2e-18 66.7 7.8 2.7e-17 63.1 7.8 2.7 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Mid1 PF12929.7 OAJ30838.1 - 4.8e-54 184.2 0.0 7.3e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 OAJ30838.1 - 0.013 16.1 2.2 0.046 14.3 0.2 2.3 2 0 0 2 2 2 0 Fz domain MRP-S25 PF13741.6 OAJ30839.1 - 2.3e-48 164.8 0.1 2.9e-47 161.1 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 OAJ30839.1 - 2.1e-06 28.0 0.3 0.009 16.3 0.0 2.5 1 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 STG PF15809.5 OAJ30839.1 - 0.022 14.8 1.0 0.04 14.0 1.0 1.3 1 0 0 1 1 1 0 Simian taste bud-specific gene product family SR-25 PF10500.9 OAJ30839.1 - 0.33 10.6 8.5 0.58 9.7 8.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GN3L_Grn1 PF08701.11 OAJ30840.1 - 7.6e-25 86.8 17.3 7.6e-25 86.8 17.3 2.4 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase zf-C2H2 PF00096.26 OAJ30841.1 - 0.00037 20.8 9.1 0.031 14.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ30841.1 - 0.0011 19.4 10.3 0.0029 18.0 1.7 2.9 2 0 0 2 2 2 2 Zinc-finger double domain GTP_EFTU PF00009.27 OAJ30842.1 - 3.4e-49 167.1 0.0 5.7e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 OAJ30842.1 - 3.8e-21 74.9 0.3 6.6e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Elongation Factor G, domain II EFG_C PF00679.24 OAJ30842.1 - 9.5e-16 57.6 0.3 4.1e-08 33.1 0.0 2.5 1 1 1 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 OAJ30842.1 - 1.8e-08 34.6 0.0 5.4e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 OAJ30842.1 - 0.00065 19.5 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 OAJ30842.1 - 0.016 15.3 0.4 0.056 13.5 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase EFG_IV PF03764.18 OAJ30842.1 - 0.023 14.5 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor G, domain IV AvrPtoB_bdg PF16847.5 OAJ30842.1 - 0.027 15.0 0.0 0.077 13.5 0.0 1.7 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain PPR_1 PF12854.7 OAJ30844.1 - 0.0057 16.3 0.1 0.0095 15.6 0.1 1.3 1 0 0 1 1 1 1 PPR repeat PPR PF01535.20 OAJ30844.1 - 0.01 16.0 0.0 0.063 13.5 0.0 2.2 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 OAJ30844.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family dCMP_cyt_deam_1 PF00383.23 OAJ30845.1 - 0.029 14.3 0.0 0.075 12.9 0.0 1.7 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region F_actin_cap_B PF01115.17 OAJ30846.1 - 4.8e-81 271.9 0.0 5.8e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit AdoHcyase PF05221.17 OAJ30847.1 - 3.8e-133 443.2 0.0 1.7e-74 250.7 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 OAJ30847.1 - 6.7e-83 276.6 2.1 1e-82 276.0 2.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 OAJ30847.1 - 1e-08 34.8 0.1 2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 OAJ30847.1 - 0.00075 19.1 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 OAJ30847.1 - 0.0039 17.4 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 OAJ30847.1 - 0.065 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding ANAPC4_WD40 PF12894.7 OAJ30848.1 - 8.2e-09 35.7 0.0 0.33 11.3 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ30848.1 - 2.8e-08 34.3 6.1 0.057 14.3 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ30848.1 - 9.5e-07 29.1 0.7 0.00061 20.2 0.0 3.8 3 0 0 3 3 3 2 PQQ-like domain polyprenyl_synt PF00348.17 OAJ30849.1 - 7.3e-61 205.4 0.0 3.1e-34 118.2 0.0 3.0 2 2 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 OAJ30849.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Clat_adaptor_s PF01217.20 OAJ30850.1 - 1.3e-54 184.0 0.2 1.5e-54 183.8 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAXNEB PF05625.11 OAJ30852.1 - 8.9e-29 100.8 0.0 3.6e-25 88.9 0.0 3.6 2 1 0 2 2 2 2 PAXNEB protein 2OG-FeII_Oxy_2 PF13532.6 OAJ30855.1 - 8.1e-26 91.4 0.0 1.3e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSP90 PF00183.18 OAJ30856.1 - 2e-51 175.5 0.2 3.6e-34 118.6 0.4 2.2 1 1 1 2 2 2 2 Hsp90 protein Scm3 PF10384.9 OAJ30856.1 - 4.4e-07 29.5 0.8 2.7e-06 27.0 0.8 2.2 1 1 0 1 1 1 1 Centromere protein Scm3 TRAM_LAG1_CLN8 PF03798.16 OAJ30857.1 - 5.2e-41 140.6 17.6 6.4e-41 140.3 17.6 1.1 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 OAJ30857.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein Oxysterol_BP PF01237.18 OAJ30858.1 - 1.2e-43 149.4 14.8 6.5e-27 94.3 2.4 4.1 2 1 1 3 3 3 2 Oxysterol-binding protein Pinin_SDK_memA PF04696.13 OAJ30858.1 - 0.68 10.0 8.3 0.11 12.5 1.7 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region gag-asp_proteas PF13975.6 OAJ30859.1 - 0.029 14.9 0.0 0.58 10.7 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ30859.1 - 0.096 13.3 0.0 0.38 11.4 0.0 2.1 1 1 1 2 2 2 0 Aspartyl protease Amidohydro_1 PF01979.20 OAJ30860.1 - 3.6e-59 200.8 0.0 2e-38 132.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 OAJ30860.1 - 2.3e-07 30.7 0.1 0.00065 19.3 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 OAJ30860.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.25 OAJ30861.1 - 1.8e-69 234.1 0.0 4.5e-69 232.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30861.1 - 3.2e-52 177.4 0.0 4.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30861.1 - 1.9e-06 27.4 0.0 0.00021 20.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like CH PF00307.31 OAJ30861.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Zn_ribbon_17 PF17120.5 OAJ30861.1 - 0.00035 20.1 3.7 0.00064 19.3 3.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 OAJ30861.1 - 0.00061 19.6 7.5 0.0011 18.8 7.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CDC24 PF06395.11 OAJ30861.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin PHD PF00628.29 OAJ30861.1 - 0.44 10.5 7.1 0.81 9.6 7.1 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 OAJ30861.1 - 9.6 6.2 7.9 18 5.4 7.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TPR_12 PF13424.6 OAJ30862.1 - 0.00034 20.8 13.5 0.028 14.7 0.7 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ30862.1 - 0.00075 19.3 1.7 7 6.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 OAJ30862.1 - 0.0091 16.0 0.3 0.4 10.8 0.2 2.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 OAJ30862.1 - 0.067 13.3 14.8 1 9.7 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ30862.1 - 0.12 12.3 8.2 19 5.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ30862.1 - 0.32 11.3 3.8 13 6.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 OAJ30863.1 - 4.2e-10 39.5 10.3 4e-05 23.8 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ30863.1 - 6.5e-05 23.2 2.1 6.5e-05 23.2 2.1 3.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ30863.1 - 0.00024 21.7 9.0 0.16 12.9 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ30863.1 - 0.026 15.2 6.4 2.4 8.8 0.1 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain NTP_transf_2 PF01909.23 OAJ30864.1 - 3.4e-05 24.0 0.0 6.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 OAJ30864.1 - 0.027 14.5 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3395 PF11875.8 OAJ30865.1 - 8e-41 139.5 0.0 1.7e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 OAJ30865.1 - 1e-20 73.6 0.7 1e-20 73.6 0.7 2.0 2 0 0 2 2 2 1 DnaJ domain DDE_3 PF13358.6 OAJ30866.1 - 9.2e-27 93.6 0.0 1.7e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_32 PF13565.6 OAJ30866.1 - 1.4e-06 28.8 0.2 0.0005 20.6 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 OAJ30866.1 - 6.9e-06 25.6 0.6 1.7e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix rve PF00665.26 OAJ30866.1 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_Tc3_2 PF01498.18 OAJ30866.1 - 0.017 15.3 1.5 0.056 13.7 0.1 2.3 2 0 0 2 2 2 0 Transposase HTH_7 PF02796.15 OAJ30866.1 - 0.025 14.7 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_1 PF01527.20 OAJ30866.1 - 0.038 14.3 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 Transposase RNB PF00773.19 OAJ30868.1 - 3.5e-96 322.4 0.0 5.8e-96 321.6 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 OAJ30868.1 - 5.1e-22 78.0 0.2 5.1e-22 78.0 0.2 1.9 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 OAJ30868.1 - 1.2e-21 76.4 0.0 2.7e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 OAJ30868.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain DUF1751 PF08551.10 OAJ30870.1 - 9.3e-26 90.3 7.2 1.7e-25 89.4 7.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 OAJ30870.1 - 0.0013 18.7 11.4 0.0029 17.6 11.4 1.6 1 0 0 1 1 1 1 Rhomboid family ETF PF01012.21 OAJ30871.1 - 2.1e-42 145.1 3.9 2.9e-42 144.6 3.9 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Rad51 PF08423.11 OAJ30872.1 - 0.1 11.9 0.0 10 5.3 0.0 2.1 2 0 0 2 2 2 0 Rad51 HRDC PF00570.23 OAJ30872.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 HRDC domain TetR_C_28 PF17937.1 OAJ30872.1 - 0.19 12.2 2.5 0.66 10.5 0.6 2.4 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HTH_10 PF04967.12 OAJ30873.1 - 0.025 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain IGR PF09597.10 OAJ30874.1 - 3e-09 36.8 0.2 3e-09 36.8 0.2 2.5 3 1 0 3 3 3 1 IGR protein motif SLT PF01464.20 OAJ30875.1 - 0.00031 20.4 0.0 0.053 13.2 0.0 2.4 2 0 0 2 2 2 2 Transglycosylase SLT domain DEAD PF00270.29 OAJ30876.1 - 3.2e-41 141.0 0.0 5.9e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ30876.1 - 5.8e-25 87.8 0.0 2e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 OAJ30876.1 - 2.1e-17 63.1 1.5 2.1e-17 63.1 1.5 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ResIII PF04851.15 OAJ30876.1 - 0.00012 22.1 0.0 0.00041 20.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NECFESHC PF16621.5 OAJ30876.1 - 0.0041 17.1 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 GHMP_kinases_C PF08544.13 OAJ30877.1 - 1.3e-11 44.7 0.0 2.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 OAJ30877.1 - 2.4e-06 27.7 0.8 5.8e-06 26.5 0.1 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF3914 PF13053.6 OAJ30877.1 - 0.028 14.8 0.0 0.073 13.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3914) DUF4142 PF13628.6 OAJ30877.1 - 0.069 13.4 0.1 4.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) Ribosomal_L7Ae PF01248.26 OAJ30878.1 - 2.5e-22 78.4 0.0 2.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L37e PF01907.19 OAJ30879.1 - 3.2e-26 91.3 13.6 5.7e-26 90.4 13.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.18 OAJ30879.1 - 0.013 15.5 0.4 0.014 15.4 0.4 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.19 OAJ30879.1 - 0.075 13.0 0.8 0.11 12.6 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA EnY2 PF10163.9 OAJ30880.1 - 7.5e-12 45.5 0.0 1.9e-11 44.2 0.0 1.6 1 1 1 2 2 2 1 Transcription factor e(y)2 DUF2722 PF10846.8 OAJ30880.1 - 0.023 13.6 1.0 0.018 14.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Prp18 PF02840.15 OAJ30880.1 - 0.028 14.5 0.7 0.085 12.9 0.9 1.7 1 1 1 2 2 2 0 Prp18 domain RmuC PF02646.16 OAJ30880.1 - 0.049 12.8 3.6 0.056 12.6 3.6 1.1 1 0 0 1 1 1 0 RmuC family Ten1 PF12658.7 OAJ30880.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Telomere capping, CST complex subunit Spt20 PF12090.8 OAJ30880.1 - 0.22 11.1 6.6 0.23 11.0 6.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF2967 PF11179.8 OAJ30880.1 - 2.3 6.2 5.1 2 6.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PRKG1_interact PF15898.5 OAJ30882.1 - 0.0032 18.3 9.6 0.0032 18.3 9.6 9.5 3 1 7 10 10 10 2 cGMP-dependent protein kinase interacting domain Cep57_CLD_2 PF14197.6 OAJ30882.1 - 0.0058 16.7 11.1 0.0058 16.7 11.1 11.5 4 2 6 10 10 10 1 Centrosome localisation domain of PPC89 SOGA PF11365.8 OAJ30882.1 - 0.016 16.3 5.0 0.016 16.3 5.0 9.1 2 1 8 10 10 10 0 Protein SOGA DASH_Dad1 PF08649.10 OAJ30882.1 - 0.26 11.5 1.2 3.3 8.0 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad1 Alg6_Alg8 PF03155.15 OAJ30883.1 - 3e-116 389.3 5.0 9.5e-86 288.7 0.8 2.4 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family ALG3 PF05208.13 OAJ30883.1 - 0.9 8.9 4.8 7.3 5.9 0.3 2.2 1 1 1 2 2 2 0 ALG3 protein Glucan_synthase PF02364.15 OAJ30884.1 - 0 1303.9 0.0 0 1303.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 OAJ30884.1 - 3.1e-40 137.5 0.0 8.2e-40 136.1 0.0 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Mucin15 PF15672.5 OAJ30884.1 - 0.26 10.7 0.0 0.42 10.1 0.0 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DASH_Duo1 PF08651.10 OAJ30885.1 - 4.7e-17 61.5 0.0 7.1e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 TraT PF05818.12 OAJ30885.1 - 0.18 11.5 4.1 0.32 10.7 4.1 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein AAA_22 PF13401.6 OAJ30886.1 - 2e-12 47.6 0.0 4.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 OAJ30886.1 - 1.3e-09 38.5 0.1 5e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ30886.1 - 3.8e-06 27.4 0.6 2e-05 25.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain TniB PF05621.11 OAJ30886.1 - 6.6e-06 25.7 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.12 OAJ30886.1 - 0.00032 20.7 0.0 0.0008 19.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_lid_10 PF17872.1 OAJ30886.1 - 0.00037 20.6 0.1 0.00086 19.4 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_33 PF13671.6 OAJ30886.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 OAJ30886.1 - 0.06 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 OAJ30886.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 OAJ30886.1 - 0.12 12.7 0.1 0.3 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAJ30886.1 - 0.21 11.4 0.0 1.4 8.7 0.0 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Glucosamine_iso PF01182.20 OAJ30887.1 - 4.2e-75 252.5 0.0 5.1e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF5510 PF17629.2 OAJ30888.1 - 0.026 14.4 1.3 0.041 13.8 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5510) MFS_1 PF07690.16 OAJ30889.1 - 1.7e-06 27.3 14.6 0.00079 18.5 0.9 4.2 4 0 0 4 4 4 2 Major Facilitator Superfamily FAM176 PF14851.6 OAJ30889.1 - 0.061 13.0 1.0 1.2 8.8 0.2 3.1 3 0 0 3 3 3 0 FAM176 family Sugar_tr PF00083.24 OAJ30889.1 - 0.11 11.4 3.0 0.66 8.8 0.5 3.2 4 1 1 5 5 5 0 Sugar (and other) transporter Orf78 PF06024.12 OAJ30889.1 - 0.35 11.2 1.7 3.4 8.0 0.6 2.9 3 0 0 3 3 3 0 Orf78 (ac78) TRAP_alpha PF03896.16 OAJ30889.1 - 0.55 9.4 1.3 1.7 7.8 0.3 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 OAJ30889.1 - 0.71 9.1 10.2 1.7 7.9 0.3 2.3 2 0 0 2 2 2 0 BUD22 Tub_N PF16322.5 OAJ30889.1 - 1 9.7 6.1 22 5.3 3.0 2.7 2 1 0 2 2 2 0 Tubby N-terminal Sporozoite_P67 PF05642.11 OAJ30889.1 - 4.3 5.3 5.4 7.8 4.4 2.7 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.13 OAJ30889.1 - 9.1 6.1 6.7 3.2 7.6 1.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region tRNA-synt_2b PF00587.25 OAJ30890.1 - 1.7e-40 138.9 0.0 3.1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 OAJ30890.1 - 7.3e-12 45.3 0.1 3.6e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Anticodon binding domain UbiA PF01040.18 OAJ30891.1 - 2.3e-50 171.2 24.6 2.9e-48 164.4 24.6 2.2 1 1 0 1 1 1 1 UbiA prenyltransferase family TIP49_C PF17856.1 OAJ30891.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 AAA-lid domain NIF PF03031.18 OAJ30892.1 - 2.4e-40 137.8 0.0 3.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HORMA PF02301.18 OAJ30893.1 - 3.3e-27 95.5 0.0 3.8e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Vps5 PF09325.10 OAJ30895.1 - 0.074 12.6 2.7 0.073 12.6 0.9 1.8 2 0 0 2 2 2 0 Vps5 C terminal like Nop14 PF04147.12 OAJ30896.1 - 4.6 5.3 17.5 6.2 4.9 17.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ30896.1 - 8.3 4.6 11.8 11 4.2 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1793 PF08760.11 OAJ30897.1 - 1.7e-65 220.6 1.0 3.4e-65 219.5 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 OAJ30897.1 - 4.7e-63 211.9 0.0 8.1e-63 211.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 OAJ30897.1 - 2.8e-20 73.1 0.1 2.8e-20 73.1 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5127) Ccdc124 PF06244.12 OAJ30898.1 - 3.5e-24 85.8 28.5 1.4e-22 80.6 28.5 2.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HTH_WhiA PF02650.14 OAJ30898.1 - 0.28 11.5 6.6 4.6 7.7 0.1 2.8 2 1 1 3 3 3 0 WhiA C-terminal HTH domain DUF3153 PF11353.8 OAJ30898.1 - 0.46 10.0 1.7 0.57 9.7 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3153) Toprim_2 PF13155.6 OAJ30898.1 - 3.9 8.0 7.3 1.3 9.5 0.7 3.2 3 1 0 3 3 3 0 Toprim-like Cript PF10235.9 OAJ30899.1 - 4.4e-26 91.3 6.4 4.4e-26 91.3 6.4 1.9 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 OAJ30899.1 - 0.015 15.6 7.2 0.015 15.6 7.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 OAJ30899.1 - 0.3 11.5 9.4 0.16 12.4 4.8 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal zinc_ribbon_2 PF13240.6 OAJ30899.1 - 0.89 9.4 12.4 0.23 11.2 2.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain HSP70 PF00012.20 OAJ30900.1 - 1.8e-64 218.0 0.4 1.1e-38 132.9 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein Actin PF00022.19 OAJ30900.1 - 0.001 17.8 0.0 0.33 9.5 0.0 2.2 2 0 0 2 2 2 2 Actin DUF4611 PF15387.6 OAJ30900.1 - 0.38 11.0 4.4 1.1 9.5 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) An_peroxidase PF03098.15 OAJ30901.1 - 1.6e-30 106.2 0.0 3.5e-21 75.4 0.0 4.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 OAJ30901.1 - 3.8e-15 55.6 0.0 4.6e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome P450 RINGv PF12906.7 OAJ30902.1 - 8.8e-15 54.6 11.3 1.6e-14 53.7 11.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 OAJ30902.1 - 0.11 12.8 10.6 0.23 11.8 10.6 1.5 1 0 0 1 1 1 0 Ring finger domain DUF2968 PF11180.8 OAJ30902.1 - 1.2 8.7 4.6 2.8 7.6 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HemY_N PF07219.13 OAJ30902.1 - 1.8 8.8 8.5 0.79 10.0 0.4 3.4 3 0 0 3 3 3 0 HemY protein N-terminus FANCL_C PF11793.8 OAJ30902.1 - 4.2 7.6 8.5 10 6.4 8.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Serglycin PF04360.12 OAJ30902.1 - 5.2 7.0 6.1 10 6.0 6.1 1.4 1 0 0 1 1 1 0 Serglycin Actin PF00022.19 OAJ30903.1 - 4.1e-112 374.8 0.0 3.3e-111 371.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ30903.1 - 0.029 13.2 0.0 0.24 10.2 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein PilX_N PF14341.6 OAJ30904.1 - 0.06 13.3 1.8 0.16 11.9 1.8 1.8 1 0 0 1 1 1 0 PilX N-terminal Abhydrolase_1 PF00561.20 OAJ30906.1 - 2.4e-17 63.4 1.6 3e-13 50.0 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ30906.1 - 6.9e-11 41.9 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ30906.1 - 7.9e-10 39.7 1.3 7.9e-10 39.7 1.3 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 OAJ30906.1 - 6.5e-05 21.8 0.0 8.4e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 OAJ30906.1 - 7.9e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 OAJ30906.1 - 0.0021 17.9 0.1 0.044 13.6 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase GTP_cyclohydroI PF01227.22 OAJ30907.1 - 4.6e-75 251.0 0.1 7.5e-75 250.3 0.1 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 OAJ30907.1 - 0.002 18.3 0.0 0.0071 16.5 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 OAJ30907.1 - 0.04 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Hamartin PF04388.12 OAJ30907.1 - 3.4 6.2 8.9 4.5 5.8 8.9 1.2 1 0 0 1 1 1 0 Hamartin protein BolA PF01722.18 OAJ30908.1 - 3.8e-12 46.3 0.0 1e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein HA2 PF04408.23 OAJ30909.1 - 3e-24 85.4 0.0 3e-23 82.2 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 OAJ30909.1 - 3.5e-13 49.7 0.0 7.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 OAJ30909.1 - 2.7e-10 40.6 0.2 3e-09 37.2 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 OAJ30909.1 - 2.5e-06 27.4 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 OAJ30909.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 OAJ30909.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 OAJ30909.1 - 0.032 14.6 1.1 0.54 10.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Inhibitor_I53 PF11714.8 OAJ30909.1 - 2.3 8.4 7.3 1.7 8.9 2.2 3.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Pyr_redox_2 PF07992.14 OAJ30910.1 - 4.9e-29 101.5 1.5 6.2e-29 101.2 1.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ30910.1 - 3.4e-11 43.0 1.1 6.8e-10 38.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ30910.1 - 1.4e-09 38.3 0.3 8.3e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ30910.1 - 1.1e-05 25.7 0.8 0.096 13.0 0.0 2.9 3 0 0 3 3 3 2 TrkA-N domain K_oxygenase PF13434.6 OAJ30910.1 - 1.6e-05 24.3 1.3 0.00015 21.1 0.1 2.7 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OAJ30910.1 - 6.9e-05 23.2 4.0 0.0064 16.9 0.1 3.3 3 1 0 3 3 3 1 Putative NAD(P)-binding Trp_halogenase PF04820.14 OAJ30910.1 - 0.00055 18.9 1.1 0.0063 15.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OAJ30910.1 - 0.0028 17.7 2.5 1.6 8.7 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 OAJ30910.1 - 0.0036 17.5 0.1 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ30910.1 - 0.0085 15.7 7.0 0.41 10.2 0.2 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 OAJ30910.1 - 0.01 15.1 0.8 0.19 10.9 0.1 2.3 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.21 OAJ30910.1 - 0.011 15.1 0.1 3 7.1 0.1 2.4 2 0 0 2 2 2 0 ThiF family Sacchrp_dh_NADP PF03435.18 OAJ30910.1 - 0.049 13.9 0.4 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAJ30910.1 - 0.069 13.2 2.1 3.1 7.9 0.1 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 OAJ30910.1 - 0.077 12.0 0.8 3.4 6.6 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 OAJ30910.1 - 0.17 10.5 3.1 3.3 6.3 0.1 3.4 2 1 2 4 4 4 0 HI0933-like protein NDK PF00334.19 OAJ30911.1 - 3.3e-50 169.6 0.0 4.3e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ADH_zinc_N PF00107.26 OAJ30912.1 - 5.2e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ30912.1 - 0.0069 17.4 0.0 0.015 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.25 OAJ30913.1 - 1.6e-71 240.8 0.0 1.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30913.1 - 1.9e-33 115.9 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 OAJ30913.1 - 0.00051 19.1 0.0 0.00071 18.6 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ30913.1 - 0.00061 19.8 0.0 0.00086 19.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 OAJ30913.1 - 0.00085 18.7 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 OAJ30913.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 OAJ30913.1 - 0.066 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 OAJ30914.1 - 2.3e-20 72.5 0.1 5.3e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 OAJ30914.1 - 2.3e-12 46.0 12.9 0.017 15.2 1.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ30914.1 - 2.6e-12 47.0 16.7 0.00056 20.4 0.2 5.5 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ30914.1 - 7.7e-12 44.5 4.5 0.0008 19.1 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ30914.1 - 1.3e-11 44.0 2.3 0.0041 17.4 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ30914.1 - 5.4e-11 42.5 14.6 1.1e-05 25.4 0.7 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ30914.1 - 1.3e-09 38.5 29.7 5.4e-05 23.8 0.6 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ30914.1 - 4e-09 36.5 21.2 0.016 15.9 2.9 6.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ30914.1 - 3.8e-07 29.8 2.8 4.7 7.7 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ30914.1 - 4.8e-06 26.2 5.4 0.0014 18.3 0.2 4.1 3 1 1 4 4 3 1 TPR repeat ANAPC3 PF12895.7 OAJ30914.1 - 0.0014 18.8 6.0 1 9.7 0.1 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 OAJ30914.1 - 0.0065 16.8 9.3 1 9.8 0.1 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat PknG_TPR PF16918.5 OAJ30914.1 - 0.027 13.2 9.0 0.02 13.6 3.6 2.8 2 1 1 3 3 3 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 OAJ30914.1 - 0.042 14.3 1.1 0.042 14.3 1.1 4.1 2 1 2 5 5 5 0 Bacterial transcriptional activator domain CYLD_phos_site PF16607.5 OAJ30914.1 - 0.087 12.7 3.0 0.071 13.0 0.7 1.9 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured RPT PF13446.6 OAJ30914.1 - 0.11 12.5 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_12 PF13424.6 OAJ30914.1 - 0.24 11.7 14.5 4.7 7.6 0.3 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ30914.1 - 0.4 10.8 5.8 11 6.3 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3808 PF10300.9 OAJ30914.1 - 0.57 8.9 4.0 3.5 6.3 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.6 OAJ30914.1 - 0.79 9.8 5.6 4.7 7.4 0.2 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Pex19 PF04614.12 OAJ30914.1 - 2.7 7.7 9.4 1.1 8.9 4.0 2.1 2 0 0 2 2 2 0 Pex19 protein family TPR_6 PF13174.6 OAJ30914.1 - 3.5 8.5 16.2 18 6.2 0.0 7.2 8 1 0 8 8 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 OAJ30914.1 - 6.8 7.2 9.1 20 5.6 0.2 3.6 3 1 0 4 4 4 0 Alkyl sulfatase dimerisation Abhydro_lipase PF04083.16 OAJ30915.1 - 2.7e-15 55.7 0.0 5.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 OAJ30915.1 - 2.9e-07 30.4 0.1 6.7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ30915.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 COX4 PF02936.14 OAJ30916.1 - 1.6e-32 112.4 0.0 2.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Pkinase PF00069.25 OAJ30917.1 - 7.1e-73 245.2 0.0 8e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ30917.1 - 1.1e-31 110.1 0.0 1.4e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ30917.1 - 6e-05 22.5 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 OAJ30917.1 - 0.00048 19.2 0.1 0.0007 18.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 OAJ30917.1 - 0.00091 19.2 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ30917.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 OAJ30917.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSBA PF01323.20 OAJ30918.1 - 2.7e-24 86.0 0.0 3.8e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Formyl_trans_N PF00551.19 OAJ30919.1 - 4.6e-18 65.6 0.0 6.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 OAJ30919.1 - 2.6e-08 34.0 0.0 5.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DKCLD PF08068.12 OAJ30920.1 - 6.2e-33 112.7 0.3 5e-32 109.8 0.6 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 OAJ30920.1 - 1.5e-23 83.8 0.2 2.7e-20 73.3 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 OAJ30920.1 - 5.5e-22 77.7 0.4 9.7e-22 76.9 0.4 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 OAJ30920.1 - 1.4e-19 69.8 0.7 3.1e-19 68.7 0.7 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 OAJ30920.1 - 0.0037 17.5 0.0 0.0088 16.3 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain SR-25 PF10500.9 OAJ30920.1 - 0.14 11.8 20.3 0.25 10.9 20.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LYRIC PF15686.5 OAJ30920.1 - 2 7.9 28.5 3 7.3 28.5 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Ima1_N PF09779.9 OAJ30921.1 - 8.6e-24 84.9 1.4 3.6e-23 82.9 0.2 2.5 2 0 0 2 2 2 1 Ima1 N-terminal domain Sporozoite_P67 PF05642.11 OAJ30921.1 - 0.046 11.8 10.2 0.068 11.3 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OAJ30921.1 - 0.6 8.2 9.6 1 7.5 9.6 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MTS PF05175.14 OAJ30922.1 - 6.8e-07 29.0 0.0 0.00034 20.2 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 OAJ30922.1 - 0.024 15.3 0.0 0.047 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 OAJ30922.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA-synt_2 PF00152.20 OAJ30924.1 - 4.9e-76 255.8 0.1 6.4e-76 255.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ30924.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ30924.1 - 0.065 12.7 0.5 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) NIF PF03031.18 OAJ30925.1 - 3.3e-19 69.2 0.0 1.5e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase BRCT PF00533.26 OAJ30925.1 - 8.2e-06 26.1 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 OAJ30925.1 - 2.2e-05 24.3 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain SDA1 PF05285.12 OAJ30925.1 - 0.005 16.3 3.0 0.005 16.3 3.0 3.4 3 0 0 3 3 3 2 SDA1 Ustilago_mating PF05722.12 OAJ30925.1 - 0.25 10.8 5.5 0.029 13.9 1.0 1.7 2 0 0 2 2 2 0 Ustilago B locus mating-type protein Hydrolase_4 PF12146.8 OAJ30926.1 - 4.5e-39 134.1 0.1 7.3e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ30926.1 - 4.5e-12 46.2 0.2 8.3e-10 38.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 OAJ30926.1 - 2.1e-10 41.6 0.2 3.3e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 OAJ30926.1 - 0.00053 19.7 0.0 0.0049 16.5 0.0 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Asp2 PF16929.5 OAJ30926.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter APG6_N PF17675.1 OAJ30927.1 - 1.3 9.5 3.2 0.54 10.8 0.8 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_L22e PF01776.17 OAJ30928.1 - 1.8e-44 150.6 0.1 2e-44 150.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family SNF2_N PF00176.23 OAJ30929.1 - 1e-67 228.3 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ30929.1 - 5.7e-17 62.1 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ30929.1 - 1.8e-06 28.1 0.0 3.4e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 OAJ30929.1 - 0.00018 21.3 11.3 0.00036 20.3 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ30929.1 - 0.00084 19.2 13.8 0.0016 18.2 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 OAJ30929.1 - 0.00091 19.0 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 OAJ30929.1 - 0.013 15.8 13.9 0.027 14.8 13.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 OAJ30929.1 - 0.041 13.8 14.3 0.083 12.9 14.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DEAD_2 PF06733.15 OAJ30929.1 - 0.11 12.2 0.1 0.75 9.4 0.1 2.2 1 1 0 1 1 1 0 DEAD_2 zf-C3HC4_2 PF13923.6 OAJ30929.1 - 0.28 11.1 13.1 0.63 9.9 13.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RTC4 PF14474.6 OAJ30934.1 - 3e-12 46.8 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain SBF PF01758.16 OAJ30934.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family SDA1 PF05285.12 OAJ30935.1 - 0.00028 20.4 8.4 0.00029 20.4 8.4 1.2 1 0 0 1 1 1 1 SDA1 BSP_II PF05432.11 OAJ30935.1 - 0.0012 18.6 12.1 0.002 17.9 12.1 1.4 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 OAJ30935.1 - 0.0024 16.2 12.1 0.0025 16.1 12.1 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4637 PF15470.6 OAJ30935.1 - 0.065 13.0 13.3 0.11 12.3 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 OAJ30935.1 - 0.067 12.5 13.6 0.075 12.4 13.6 1.2 1 0 0 1 1 1 0 BUD22 PTPRCAP PF15713.5 OAJ30935.1 - 0.16 12.3 17.7 0.33 11.2 17.7 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mpp10 PF04006.12 OAJ30935.1 - 0.18 10.2 13.4 0.25 9.7 13.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Pox_Ag35 PF03286.14 OAJ30935.1 - 1.6 8.5 9.9 4.1 7.1 10.1 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CDC45 PF02724.14 OAJ30935.1 - 2.1 6.5 13.3 2.7 6.2 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 OAJ30935.1 - 3.7 7.9 5.8 8.5 6.8 5.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 OAJ30935.1 - 4.5 5.9 4.8 5.6 5.6 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 OAJ30935.1 - 6 4.8 26.3 7.7 4.5 26.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 OAJ30935.1 - 9.5 4.4 6.5 12 4.1 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RVT_2 PF07727.14 OAJ30936.1 - 1.5e-65 221.3 0.0 2e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ30936.1 - 1.5e-20 73.5 0.0 3.4e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ30936.1 - 0.00072 19.3 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain SUKH-4 PF14435.6 OAJ30936.1 - 0.035 14.2 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 SUKH-4 immunity protein zf-CCHC PF00098.23 OAJ30937.1 - 9.5e-05 22.3 5.9 0.00015 21.7 5.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ30937.1 - 0.0032 17.1 0.1 0.0051 16.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 OAJ30937.1 - 0.011 15.7 1.2 0.021 14.8 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle LON_substr_bdg PF02190.16 OAJ30938.1 - 5.9e-25 88.4 0.0 2.8e-24 86.2 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 OAJ30938.1 - 5.2e-15 55.0 21.2 6.4e-11 41.9 9.6 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ30938.1 - 1e-11 44.7 19.7 2.1e-06 27.7 3.6 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ30938.1 - 2.3e-10 40.2 17.3 5.7e-07 29.3 5.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ30938.1 - 6.8e-10 38.9 20.8 7.9e-06 25.9 3.7 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 OAJ30938.1 - 1.6e-09 37.9 20.4 6.6e-07 29.6 9.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 OAJ30938.1 - 4.6e-09 36.0 21.1 5.9e-05 22.9 8.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ30938.1 - 1.1e-08 34.9 19.0 3.3e-05 23.8 8.0 2.4 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 OAJ30938.1 - 2.4e-08 33.7 19.6 2.1e-06 27.5 7.0 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 OAJ30938.1 - 0.0015 18.6 14.1 0.003 17.6 3.4 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_4 PF14570.6 OAJ30938.1 - 0.0045 16.8 3.5 0.0045 16.8 3.5 3.1 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 OAJ30938.1 - 0.021 14.7 17.1 0.045 13.6 1.4 3.0 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 OAJ30938.1 - 0.21 11.9 13.3 0.047 14.0 6.3 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-P11 PF03854.14 OAJ30938.1 - 5.6 6.7 14.6 0.17 11.6 6.9 2.2 2 0 0 2 2 2 0 P-11 zinc finger CLTH PF10607.9 OAJ30939.1 - 1.3e-18 67.3 0.0 5.8e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF4248 PF14053.6 OAJ30939.1 - 0.096 12.7 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Kelch_4 PF13418.6 OAJ30940.1 - 5.1e-11 42.4 1.8 0.02 14.9 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ30940.1 - 1.2e-10 41.3 2.1 0.051 13.9 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 OAJ30940.1 - 8.7e-08 32.0 0.1 0.00012 21.9 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 OAJ30940.1 - 2.4e-06 27.0 0.3 0.77 9.4 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 OAJ30940.1 - 4.6e-05 23.6 11.6 5.9e-05 23.3 0.1 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_2 PF07646.15 OAJ30940.1 - 0.00013 21.7 0.3 0.012 15.6 0.1 3.6 2 0 0 2 2 2 1 Kelch motif DUF3712 PF12505.8 OAJ30941.1 - 2.5e-107 354.1 43.9 5.9e-24 84.7 0.1 8.2 8 0 0 8 8 8 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 OAJ30941.1 - 8.3e-08 32.7 15.0 0.051 14.1 0.1 7.6 8 0 0 8 8 8 3 Late embryogenesis abundant protein EF1_GNE PF00736.19 OAJ30942.1 - 2.1e-32 111.2 1.4 3.4e-32 110.5 1.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 OAJ30942.1 - 1.5e-11 44.5 6.2 1.5e-11 44.5 6.2 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 OAJ30942.1 - 0.00036 20.5 0.3 0.0026 17.7 0.3 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ30942.1 - 0.00083 19.5 0.3 0.0038 17.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ30942.1 - 0.001 19.2 0.1 0.003 17.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 OAJ30942.1 - 0.011 15.5 4.3 0.015 15.1 4.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_6 PF17171.4 OAJ30942.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 OAJ30942.1 - 0.23 11.1 3.9 0.29 10.7 3.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3246 PF11596.8 OAJ30942.1 - 5.3 6.4 6.5 6.3 6.2 5.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) TEX13 PF15186.6 OAJ30943.1 - 0.59 9.8 10.3 1.4 8.6 10.3 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family MAJIN PF15077.6 OAJ30943.1 - 9.7 5.9 19.1 0.52 10.1 12.6 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein F-box-like PF12937.7 OAJ30944.1 - 3.5e-05 23.6 0.2 0.00026 20.8 0.2 2.2 1 1 0 1 1 1 1 F-box-like CENP-B_dimeris PF09026.10 OAJ30944.1 - 0.058 13.8 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain START PF01852.19 OAJ30945.1 - 0.00093 18.7 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 START domain RPA43_OB PF17875.1 OAJ30945.1 - 0.0045 17.6 0.1 2.4 8.8 0.0 3.0 2 0 0 2 2 2 2 RPA43 OB domain in RNA Pol I BSP_II PF05432.11 OAJ30945.1 - 1.9 8.1 8.6 2.5 7.7 3.1 2.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PCI PF01399.27 OAJ30946.1 - 2.3e-07 31.3 0.1 6.5e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 OAJ30946.1 - 0.12 12.5 0.1 0.37 11.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1180 PF06679.12 OAJ30946.1 - 7.7 6.9 8.9 17 5.7 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CPBP PF02517.16 OAJ30947.1 - 1.2e-17 64.0 4.7 1.2e-17 64.0 4.7 2.5 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Inositol_P PF00459.25 OAJ30948.1 - 9.6e-61 205.7 0.0 1.2e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family p450 PF00067.22 OAJ30949.1 - 2.2e-42 145.4 0.0 9.3e-25 87.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Ribonuclease_3 PF00636.26 OAJ30950.1 - 1.1e-36 125.6 0.0 2.1e-18 66.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 OAJ30950.1 - 2.2e-20 73.1 5.4 6.1e-12 45.8 0.3 3.8 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 OAJ30950.1 - 4.9e-17 62.3 0.0 1.4e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 OAJ30950.1 - 3.1e-16 59.3 0.1 3.5e-15 55.9 0.2 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain DEAD PF00270.29 OAJ30950.1 - 2.4e-08 34.0 0.0 6.6e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ30950.1 - 2.2e-07 31.1 0.0 1.1e-06 28.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.26 OAJ30950.1 - 0.0064 17.2 0.0 0.058 14.1 0.0 2.6 2 0 0 2 2 2 1 Double-stranded RNA binding motif PALP PF00291.25 OAJ30951.1 - 4.8e-48 164.1 0.4 1.7e-45 155.7 0.4 2.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LapA_dom PF06305.11 OAJ30951.1 - 0.04 13.7 0.3 0.04 13.7 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ADH_zinc_N PF00107.26 OAJ30951.1 - 0.041 13.9 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase F-box-like PF12937.7 OAJ30952.1 - 1.8e-11 43.7 0.1 1.8e-11 43.7 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 OAJ30952.1 - 7.4e-08 32.1 0.0 7.4e-08 32.1 0.0 2.4 3 0 0 3 3 3 1 F-box domain PQQ_2 PF13360.6 OAJ30952.1 - 2.9e-05 23.8 0.1 0.088 12.4 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 OAJ30952.1 - 0.00011 22.0 2.1 0.55 10.3 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat F-box_4 PF15966.5 OAJ30952.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box RXT2_N PF08595.11 OAJ30952.1 - 3.2 7.8 4.2 40 4.2 0.0 2.3 1 1 1 2 2 2 0 RXT2-like, N-terminal DUF3432 PF11914.8 OAJ30953.1 - 0.77 10.0 18.2 1.3 9.3 18.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) RuvA_N PF01330.21 OAJ30954.1 - 0.12 12.5 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 RuvA N terminal domain ABC_membrane PF00664.23 OAJ30955.1 - 2.7e-58 197.8 28.2 1.7e-32 113.2 14.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ30955.1 - 3e-54 183.3 0.0 6.4e-31 107.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ30955.1 - 2.3e-07 30.5 2.5 0.016 14.6 0.1 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 OAJ30955.1 - 1.8e-06 28.0 0.6 0.0042 17.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ30955.1 - 2.8e-06 27.8 2.3 0.066 13.6 0.0 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 OAJ30955.1 - 5.7e-06 26.0 0.2 0.0097 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ30955.1 - 3e-05 24.6 7.0 0.67 10.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 OAJ30955.1 - 5.1e-05 22.9 0.4 0.56 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 OAJ30955.1 - 5.8e-05 23.1 0.2 0.28 11.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAJ30955.1 - 8.7e-05 22.5 1.5 0.41 10.4 0.1 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 OAJ30955.1 - 0.00022 21.5 0.1 0.41 10.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 OAJ30955.1 - 0.00032 20.2 0.1 1 8.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 OAJ30955.1 - 0.00048 20.3 0.3 0.0015 18.7 0.3 1.9 1 0 0 1 1 1 1 Helicase HerA, central domain T2SSE PF00437.20 OAJ30955.1 - 0.00068 18.8 0.0 0.031 13.3 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein Dynamin_N PF00350.23 OAJ30955.1 - 0.0012 18.9 3.0 0.11 12.6 0.1 3.0 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 OAJ30955.1 - 0.0075 15.6 0.7 1 8.6 0.2 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 OAJ30955.1 - 0.0085 15.8 2.3 0.54 9.9 0.1 2.8 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 OAJ30955.1 - 0.016 14.8 1.0 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OAJ30955.1 - 0.02 15.1 0.1 6.6 7.0 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 OAJ30955.1 - 0.021 14.8 1.4 5.5 6.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 OAJ30955.1 - 0.031 14.3 0.2 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 OAJ30955.1 - 0.036 13.2 0.4 4.4 6.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OAJ30955.1 - 0.044 13.8 1.3 34 4.5 0.0 4.1 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 OAJ30955.1 - 0.085 13.3 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 OAJ30955.1 - 0.089 13.0 1.0 12 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 OAJ30955.1 - 0.096 12.4 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 OAJ30955.1 - 0.1 11.9 0.6 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 OAJ30955.1 - 0.15 10.9 1.8 0.9 8.4 0.2 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 OAJ30955.1 - 0.29 11.6 1.5 27 5.2 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 OAJ30955.1 - 0.31 11.6 1.0 9.9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_1 PF00441.24 OAJ30956.1 - 3e-28 98.9 2.4 4.7e-28 98.3 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ30956.1 - 2.9e-18 65.8 0.0 9.6e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ30956.1 - 1.5e-12 48.0 4.8 1.5e-12 48.0 4.8 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ30956.1 - 1.9e-10 41.4 0.0 3.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CPSase_L_D2 PF02786.17 OAJ30957.1 - 5.5e-83 277.6 0.1 9.6e-83 276.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 OAJ30957.1 - 9.4e-70 234.4 0.0 1.8e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 OAJ30957.1 - 1.1e-39 135.4 0.1 2.8e-39 134.1 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ30957.1 - 3.4e-31 107.5 0.0 8.3e-31 106.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 OAJ30957.1 - 3.9e-28 98.7 0.0 8.5e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 OAJ30957.1 - 1.2e-13 50.7 0.7 2.4e-13 49.7 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 OAJ30957.1 - 6.5e-11 41.9 0.5 7e-05 22.6 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 OAJ30957.1 - 3.6e-10 39.7 0.0 6.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ30957.1 - 4e-07 29.8 0.0 9.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 OAJ30957.1 - 3.5e-05 23.9 0.0 6.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ30957.1 - 4.3e-05 24.2 0.2 0.5 11.1 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 OAJ30957.1 - 9.1e-05 21.8 0.0 0.026 13.8 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 OAJ30957.1 - 0.00075 19.1 0.0 0.0024 17.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 OAJ30957.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 OAJ30957.1 - 0.0049 16.6 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Sacchrp_dh_NADP PF03435.18 OAJ30957.1 - 0.074 13.3 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain SAE2 PF08573.10 OAJ30958.1 - 2.7e-12 47.8 2.9 2.7e-12 47.8 2.9 3.7 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DctP PF03480.13 OAJ30958.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Mvb12 PF09452.10 OAJ30958.1 - 0.19 12.2 2.8 0.18 12.3 0.5 2.2 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Cyclase PF04199.13 OAJ30959.1 - 4.5e-12 46.4 0.0 9.4e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase Syntaxin_2 PF14523.6 OAJ30960.1 - 0.14 12.5 0.7 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Transposase_21 PF02992.14 OAJ30961.1 - 0.00017 20.9 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2H2_jaz PF12171.8 OAJ30961.1 - 0.21 11.9 0.9 0.7 10.2 0.9 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RVT_2 PF07727.14 OAJ30962.1 - 9.6e-41 140.0 0.0 1.3e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ30962.1 - 0.0047 16.7 0.8 0.013 15.3 0.8 1.7 1 1 0 1 1 1 1 Reverse transcriptase-like Cys_Met_Meta_PP PF01053.20 OAJ30963.1 - 1.7e-58 198.0 0.0 1.9e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PPP4R2 PF09184.11 OAJ30964.1 - 0.17 11.4 14.6 0.04 13.5 5.5 2.3 2 0 0 2 2 2 0 PPP4R2 DUF2968 PF11180.8 OAJ30964.1 - 3.3 7.3 14.2 5.2 6.7 14.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Pox_Ag35 PF03286.14 OAJ30964.1 - 6.8 6.4 18.4 0.87 9.3 6.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.19 OAJ30965.1 - 3.6 8.2 10.0 0.56 10.8 5.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L13e PF01294.18 OAJ30966.1 - 1.7e-69 233.3 6.9 2.4e-69 232.8 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Acetyltransf_1 PF00583.25 OAJ30967.1 - 1.4e-07 31.7 0.0 0.0038 17.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ30967.1 - 3e-06 27.6 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ30967.1 - 0.00012 22.0 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 OAJ30967.1 - 0.00014 21.8 0.1 0.068 13.1 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 OAJ30967.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 OAJ30967.1 - 0.096 12.8 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3419 PF11899.8 OAJ30970.1 - 8.6e-17 61.4 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Ribonuclease PF00545.20 OAJ30970.1 - 1.9e-07 31.7 0.0 5e-07 30.4 0.0 1.7 1 1 1 2 2 2 1 ribonuclease DUF3419 PF11899.8 OAJ30971.1 - 1.1e-143 479.1 0.0 1.5e-143 478.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 OAJ30971.1 - 4.7e-09 36.8 0.0 1.1e-07 32.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ30971.1 - 8.3e-08 32.8 0.0 9.6e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ30971.1 - 9.3e-08 32.1 0.0 4.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ30971.1 - 2.9e-07 30.4 0.0 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ30971.1 - 3.1e-07 30.0 0.0 4.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 OAJ30971.1 - 2.6e-05 24.9 0.0 8.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 OAJ30971.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 OAJ30971.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DnaJ PF00226.31 OAJ30972.1 - 1e-18 67.2 0.1 1.9e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DHH PF01368.20 OAJ30972.1 - 5.2e-08 33.0 0.0 2.4e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 DHH family Mucin PF01456.17 OAJ30972.1 - 0.37 10.8 15.0 0.84 9.6 15.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein MRP-L27 PF09809.9 OAJ30974.1 - 1.4e-06 28.1 0.4 2.6e-05 24.0 0.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 BING4CT PF08149.11 OAJ30976.1 - 1.4e-36 124.1 0.0 3e-34 116.7 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain Coatomer_WDAD PF04053.14 OAJ30976.1 - 0.00034 19.8 0.0 0.00051 19.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 OAJ30976.1 - 0.00084 20.1 0.3 0.084 13.8 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ30976.1 - 0.0099 16.2 0.1 4.1 7.8 0.0 4.0 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4665 PF15679.5 OAJ30976.1 - 1.9 9.1 6.1 0.21 12.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) MAGE PF01454.19 OAJ30977.1 - 2.8e-24 86.0 0.0 2.5e-22 79.6 0.0 3.3 1 1 0 1 1 1 1 MAGE family BSP_II PF05432.11 OAJ30977.1 - 8.2 6.0 29.3 2.6 7.6 19.4 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ABC_tran PF00005.27 OAJ30978.1 - 5.2e-47 159.8 0.2 5.1e-23 82.1 0.0 2.9 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 OAJ30978.1 - 1.4e-20 73.1 4.0 1.4e-20 73.1 4.0 2.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 OAJ30978.1 - 6.5e-16 59.0 8.2 0.002 18.0 0.1 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ30978.1 - 2.4e-09 38.0 7.2 0.0023 18.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.19 OAJ30978.1 - 1.1e-08 34.8 2.2 0.31 10.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 OAJ30978.1 - 1.9e-08 33.9 0.3 0.0054 16.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ30978.1 - 5.6e-07 29.6 4.2 0.0055 16.5 0.0 4.2 2 2 1 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ30978.1 - 9.8e-06 25.6 1.9 0.0085 16.2 0.2 3.3 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ30978.1 - 2.6e-05 24.7 0.0 0.25 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 OAJ30978.1 - 9.8e-05 22.7 0.0 0.27 11.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 OAJ30978.1 - 0.00027 20.7 0.7 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 OAJ30978.1 - 0.00058 20.2 0.5 0.84 9.9 0.0 3.1 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 OAJ30978.1 - 0.00091 19.2 0.5 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 OAJ30978.1 - 0.0011 18.8 4.6 0.095 12.6 0.1 3.5 4 0 0 4 4 4 1 RsgA GTPase MeaB PF03308.16 OAJ30978.1 - 0.002 17.1 0.1 0.42 9.6 0.0 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 OAJ30978.1 - 0.004 17.7 0.0 6.1 7.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ30978.1 - 0.0041 17.3 0.4 6.1 7.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 OAJ30978.1 - 0.0042 16.3 0.1 4.4 6.4 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain T2SSE PF00437.20 OAJ30978.1 - 0.0044 16.1 0.1 0.56 9.2 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.14 OAJ30978.1 - 0.0054 16.6 0.8 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 OAJ30978.1 - 0.0068 16.8 0.4 1.7 9.1 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 OAJ30978.1 - 0.014 15.8 1.1 9.1 6.7 0.1 3.1 3 0 0 3 3 3 0 RNA helicase FeoB_N PF02421.18 OAJ30978.1 - 0.016 14.7 0.0 0.57 9.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 OAJ30978.1 - 0.017 15.4 0.0 3.8 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 OAJ30978.1 - 0.018 14.4 0.2 1.8 7.8 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 OAJ30978.1 - 0.021 14.6 4.1 1.1 9.0 0.2 3.5 3 1 0 3 3 3 0 AAA domain AAA_27 PF13514.6 OAJ30978.1 - 0.024 14.2 0.1 11 5.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 OAJ30978.1 - 0.029 14.0 0.0 1.7 8.2 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 OAJ30978.1 - 0.03 14.4 11.7 1 9.4 0.3 4.2 4 2 1 5 5 4 0 Dynamin family NTPase_1 PF03266.15 OAJ30978.1 - 0.039 13.9 4.2 12 5.7 0.2 3.6 4 0 0 4 4 3 0 NTPase cobW PF02492.19 OAJ30978.1 - 0.043 13.4 1.3 5.1 6.7 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 OAJ30978.1 - 0.049 13.6 0.9 11 6.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 OAJ30978.1 - 0.059 13.6 0.0 4.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 OAJ30978.1 - 0.063 13.0 0.2 9.1 6.0 0.0 3.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 OAJ30978.1 - 0.11 11.9 0.6 6.9 6.1 0.1 3.0 4 0 0 4 4 3 0 P-loop containing dynein motor region DUF87 PF01935.17 OAJ30978.1 - 0.18 11.9 5.5 4.8 7.2 0.1 3.7 4 1 1 5 5 4 0 Helicase HerA, central domain Pox_A32 PF04665.12 OAJ30978.1 - 0.22 10.9 3.2 2.5 7.5 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein TsaE PF02367.17 OAJ30978.1 - 0.31 11.1 2.6 4.5 7.3 0.0 3.5 3 1 1 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 OAJ30978.1 - 0.54 9.5 4.5 15 4.8 0.0 3.3 4 0 0 4 4 3 0 Septin Arm PF00514.23 OAJ30979.1 - 2.3e-96 313.3 12.4 2.6e-13 49.5 0.1 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 OAJ30979.1 - 2.9e-23 82.1 3.5 6.1e-23 81.1 3.5 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 OAJ30979.1 - 4.8e-23 81.4 0.3 2.5e-05 24.6 0.0 6.8 3 1 6 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 OAJ30979.1 - 2e-22 79.3 4.7 2.8e-08 34.1 0.0 6.7 5 1 2 7 7 7 6 HEAT-like repeat Arm_3 PF16186.5 OAJ30979.1 - 3.7e-18 64.8 0.2 1.2e-17 63.2 0.2 1.9 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 OAJ30979.1 - 3.4e-17 61.1 2.6 0.00062 19.8 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_PBS PF03130.16 OAJ30979.1 - 8e-05 23.0 3.4 0.062 14.0 0.0 5.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Arm_2 PF04826.13 OAJ30979.1 - 0.00012 21.7 0.0 0.96 8.9 0.0 3.8 2 1 2 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.8 OAJ30979.1 - 0.00051 20.1 0.2 0.25 11.5 0.0 4.1 3 2 1 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.20 OAJ30979.1 - 0.0032 16.1 0.0 0.032 12.8 0.0 2.3 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.6 OAJ30979.1 - 0.0064 16.7 3.2 1.9 8.8 0.1 4.2 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 APG9 PF04109.16 OAJ30980.1 - 7.6e-195 648.5 1.0 9e-195 648.2 1.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_92 PF07971.12 OAJ30981.1 - 1.3e-95 321.1 0.2 1.7e-95 320.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 OAJ30981.1 - 1.2e-43 149.7 0.9 1.9e-43 149.1 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Cys_Met_Meta_PP PF01053.20 OAJ30982.1 - 7e-131 436.3 0.0 1.2e-130 435.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 OAJ30982.1 - 2.1e-05 23.3 0.0 2.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 OAJ30982.1 - 5.2e-05 22.4 0.0 7.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ30982.1 - 0.012 14.8 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Alliinase_C PF04864.13 OAJ30982.1 - 0.017 14.0 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Allinase NCE101 PF11654.8 OAJ30984.1 - 9.4e-19 66.9 0.0 1.4e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 DUF2934 PF11154.8 OAJ30984.1 - 0.03 14.0 0.2 0.27 10.9 0.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2934) Spb1_C PF07780.12 OAJ30985.1 - 1.7e-73 246.8 27.7 1.7e-73 246.8 27.7 3.4 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 OAJ30985.1 - 1e-55 188.6 0.2 4.1e-55 186.6 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 OAJ30985.1 - 1.9e-39 135.1 10.5 1.9e-39 135.1 10.5 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) zf-CCHC PF00098.23 OAJ30986.1 - 3.8e-05 23.6 1.2 9.1e-05 22.4 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ30986.1 - 0.00064 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF5446 PF17522.2 OAJ30986.1 - 0.012 15.7 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Copper-fist PF00649.18 OAJ30986.1 - 0.14 11.7 1.8 0.31 10.5 1.8 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-CCHC_5 PF14787.6 OAJ30986.1 - 0.17 11.6 2.4 0.31 10.8 0.6 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 OAJ30986.1 - 0.18 11.7 0.8 0.35 10.8 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.14 OAJ30987.1 - 7.9e-67 225.4 0.0 1.1e-66 224.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ30987.1 - 9e-18 64.6 0.7 3.5e-16 59.5 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ30987.1 - 2.4e-05 24.1 0.0 7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ30987.1 - 0.0026 17.5 0.4 0.032 14.0 0.0 2.8 3 0 0 3 3 3 1 Integrase core domain RVT_2 PF07727.14 OAJ30989.1 - 1.3e-68 231.2 0.0 1.9e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ30989.1 - 4.8e-17 62.3 1.3 1.6e-16 60.6 0.1 2.5 3 0 0 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ30989.1 - 9.7e-06 25.4 0.1 2.4e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 OAJ30989.1 - 0.00086 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 OAJ30989.1 - 0.038 13.8 0.0 0.16 11.7 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Polysacc_deac_1 PF01522.21 OAJ30990.1 - 1.2e-23 83.3 0.1 5.3e-23 81.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Sporozoite_P67 PF05642.11 OAJ30990.1 - 0.17 10.0 11.5 0.24 9.5 11.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SSP160 PF06933.11 OAJ30990.1 - 7.4 4.6 23.6 11 4.0 23.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IATP PF04568.12 OAJ30990.1 - 7.8 7.0 6.0 16 6.0 6.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Lectin_leg-like PF03388.13 OAJ30991.1 - 1.1e-59 201.7 0.1 1.4e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family DUF3561 PF12084.8 OAJ30991.1 - 0.016 15.2 0.1 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Lectin_legB PF00139.19 OAJ30991.1 - 0.055 13.0 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain FA_hydroxylase PF04116.13 OAJ30992.1 - 1.3e-18 67.6 6.3 1.3e-18 67.6 6.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Nup160 PF11715.8 OAJ30993.1 - 1.2e-17 63.8 0.0 3.8e-10 39.1 0.0 3.2 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Peptidase_S10 PF00450.22 OAJ30994.1 - 2.2e-110 369.9 1.3 3e-110 369.5 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Apolipoprotein PF01442.18 OAJ30994.1 - 0.00063 19.7 0.2 0.00095 19.1 0.2 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.11 OAJ30994.1 - 0.025 14.6 1.0 0.05 13.6 1.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1104 PF06518.11 OAJ30994.1 - 0.14 12.6 0.9 0.34 11.3 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Pribosyltran_N PF13793.6 OAJ30995.1 - 6.8e-43 145.3 0.4 4.4e-42 142.7 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 OAJ30995.1 - 9.1e-41 139.9 2.1 3.9e-33 115.0 0.1 3.0 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 OAJ30995.1 - 9.8e-15 54.4 0.1 7.4e-14 51.6 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HTH_Tnp_Tc5 PF03221.16 OAJ30996.1 - 1.1e-07 31.8 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_4 PF13613.6 OAJ30996.1 - 0.00031 20.4 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_Crp_2 PF13545.6 OAJ30996.1 - 0.0057 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 OAJ30996.1 - 0.0076 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 OAJ30996.1 - 0.0084 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 OAJ30996.1 - 0.0094 15.6 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 OAJ30996.1 - 0.01 15.8 0.5 0.025 14.5 0.0 1.9 2 0 0 2 2 1 1 MarR family DUF4407 PF14362.6 OAJ30996.1 - 0.011 15.1 1.8 0.019 14.3 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 OAJ30996.1 - 0.015 13.6 32.1 0.02 13.2 32.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HTH_38 PF13936.6 OAJ30996.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Plasmodium_Vir PF05795.11 OAJ30996.1 - 0.034 13.6 0.1 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 Plasmodium vivax Vir protein HTH_28 PF13518.6 OAJ30996.1 - 0.046 13.8 0.1 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain SpoIIP PF07454.11 OAJ30996.1 - 0.086 12.3 4.9 0.15 11.5 4.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HTH_24 PF13412.6 OAJ30996.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_36 PF13730.6 OAJ30996.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain eIF-3_zeta PF05091.12 OAJ30996.1 - 0.47 9.4 9.4 0.71 8.8 9.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 OAJ30996.1 - 2 7.9 41.9 0.23 11.0 34.6 2.2 2 0 0 2 2 2 0 Spt20 family TrbL PF04610.14 OAJ30997.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DEAD PF00270.29 OAJ30998.1 - 3.5e-12 46.4 0.0 6.4e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ30998.1 - 2.9e-08 34.0 0.1 5.8e-06 26.6 0.1 2.4 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ30998.1 - 0.037 14.0 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Polysacc_deac_1 PF01522.21 OAJ31000.1 - 1.6e-22 79.7 0.0 2.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase WD40 PF00400.32 OAJ31001.1 - 2.7e-30 103.9 19.0 2.4e-05 25.0 0.0 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat Utp12 PF04003.12 OAJ31001.1 - 1.8e-17 63.6 0.0 4.3e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 OAJ31001.1 - 1.4e-12 47.7 0.0 0.96 9.8 0.0 8.1 2 2 6 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ31001.1 - 0.00026 19.8 0.0 0.23 10.1 0.0 3.6 2 2 2 4 4 4 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 OAJ31001.1 - 0.0018 17.9 0.4 0.06 12.9 0.1 3.0 2 1 1 3 3 3 1 PQQ-like domain DUF1513 PF07433.11 OAJ31001.1 - 0.0055 15.8 0.2 0.36 9.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 OAJ31001.1 - 0.0093 14.5 0.0 1.7 7.1 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 OAJ31001.1 - 0.012 14.5 1.8 30 3.4 0.1 4.6 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 OAJ31001.1 - 0.016 14.9 0.0 0.086 12.6 0.0 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ PF01011.21 OAJ31001.1 - 0.022 14.7 0.1 2.6 8.1 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat PD40 PF07676.12 OAJ31001.1 - 0.38 10.8 3.9 32 4.6 0.0 5.2 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 OAJ31001.1 - 0.66 10.5 5.6 61 4.3 0.1 5.1 3 1 1 4 4 4 0 PQQ-like domain NUDIX PF00293.28 OAJ31003.1 - 0.00032 20.7 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 OAJ31004.1 - 8.7e-06 25.3 0.0 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 OAJ31004.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ31004.1 - 0.00043 19.4 0.0 0.00062 18.9 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 OAJ31004.1 - 0.0078 15.0 2.8 0.069 11.9 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 OAJ31004.1 - 0.0089 15.4 2.4 0.015 14.6 2.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAL_FSA PF00923.19 OAJ31007.1 - 1.7e-97 326.2 0.3 1.9e-97 326.1 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Aminotran_1_2 PF00155.21 OAJ31008.1 - 1.8e-80 270.9 0.0 2e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SCP2 PF02036.17 OAJ31009.1 - 1.7e-26 92.6 1.4 1.9e-26 92.5 1.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ31009.1 - 7.3e-05 23.0 0.5 8.9e-05 22.8 0.5 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ost5 PF05251.12 OAJ31010.1 - 5.4e-16 58.6 6.8 7.1e-16 58.2 6.8 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Fig1 PF12351.8 OAJ31010.1 - 0.013 15.4 0.4 0.013 15.4 0.4 1.0 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 ArfGap PF01412.18 OAJ31011.1 - 4.5e-40 136.4 0.2 4.5e-40 136.4 0.2 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NAM-associated PF14303.6 OAJ31011.1 - 0.0024 18.6 3.4 0.04 14.6 3.4 2.6 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF4175 PF13779.6 OAJ31011.1 - 0.03 12.3 16.7 0.047 11.6 16.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BBS2_C PF14782.6 OAJ31011.1 - 0.053 12.3 3.5 0.074 11.8 3.5 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal CSRNP_N PF16019.5 OAJ31011.1 - 0.41 10.5 8.9 1.1 9.2 8.9 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus RrnaAD PF00398.20 OAJ31013.1 - 5.7e-59 199.4 0.0 7.6e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 OAJ31013.1 - 1.2e-07 32.3 0.0 2.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ31013.1 - 3e-05 24.6 0.0 5.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 OAJ31013.1 - 6.8e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 OAJ31013.1 - 0.00013 21.7 0.0 0.00027 20.6 0.0 1.5 2 0 0 2 2 2 1 Nodulation protein S (NodS) MTS PF05175.14 OAJ31013.1 - 0.00028 20.5 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 OAJ31013.1 - 0.00047 20.0 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 OAJ31013.1 - 0.00087 20.0 0.0 0.0016 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31013.1 - 0.0048 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ31013.1 - 0.0059 16.4 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 OAJ31013.1 - 0.016 14.9 0.0 0.086 12.5 0.0 1.9 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.18 OAJ31013.1 - 0.046 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_28 PF02636.17 OAJ31013.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 OAJ31013.1 - 0.072 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CUE PF02845.16 OAJ31014.1 - 4.3e-09 35.9 0.0 8.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF1296 PF06972.11 OAJ31014.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Noc2 PF03715.13 OAJ31016.1 - 1.3e-108 362.8 0.3 2.7e-108 361.7 0.0 1.6 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 OAJ31016.1 - 0.13 10.5 31.0 1 7.5 0.1 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 OAJ31016.1 - 0.46 9.8 27.8 0.88 8.8 27.8 1.4 1 0 0 1 1 1 0 BUD22 RVT_3 PF13456.6 OAJ31017.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like zf-C2H2 PF00096.26 OAJ31018.1 - 5e-09 36.1 7.3 0.00044 20.6 3.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ31018.1 - 9.6e-08 32.1 9.6 2.3e-06 27.8 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ31018.1 - 6.7e-07 29.6 6.9 0.00069 20.2 3.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 OAJ31018.1 - 0.00032 20.9 4.1 0.01 16.1 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 OAJ31018.1 - 0.028 15.1 2.1 0.044 14.5 2.1 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-met PF12874.7 OAJ31018.1 - 0.038 14.4 1.8 0.062 13.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Spt46 PF17734.1 OAJ31018.1 - 0.039 13.8 0.2 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-Di19 PF05605.12 OAJ31018.1 - 0.097 13.0 1.6 0.17 12.2 1.6 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 OAJ31018.1 - 0.76 9.9 4.6 0.5 10.4 2.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Phage_integrase PF00589.22 OAJ31019.1 - 0.00046 20.0 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_4 PF13495.6 OAJ31019.1 - 0.093 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 OAJ31019.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain F-box-like PF12937.7 OAJ31021.1 - 5.9e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 OAJ31021.1 - 3.3e-06 27.7 0.0 2.4 9.2 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 OAJ31021.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 OAJ31021.1 - 0.00069 19.4 10.1 0.17 11.9 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif F-box_4 PF15966.5 OAJ31021.1 - 0.00077 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 F-box DUF4581 PF15167.6 OAJ31022.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) LRR_4 PF12799.7 OAJ31023.1 - 1.9e-05 25.0 2.4 0.0011 19.3 0.5 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAJ31023.1 - 6.2e-05 22.6 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 OAJ31023.1 - 0.18 11.6 3.2 1.7 8.4 0.7 2.5 2 1 0 2 2 2 0 Leucine rich repeat Arm PF00514.23 OAJ31025.1 - 3.3e-05 23.7 15.3 0.035 14.2 0.0 9.1 10 0 0 10 10 10 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 OAJ31025.1 - 0.0021 18.4 9.2 4.7 7.7 0.0 5.9 5 1 1 6 6 6 2 HEAT repeats V-ATPase_H_N PF03224.14 OAJ31025.1 - 0.0031 16.8 0.0 5.9 6.1 0.0 3.7 3 1 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.22 OAJ31025.1 - 0.14 12.5 11.9 1.1e+02 3.5 0.0 7.1 7 0 0 7 7 7 0 HEAT repeat Nup192 PF11894.8 OAJ31025.1 - 0.24 8.5 0.0 0.34 8.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 ATP-synt_ab PF00006.25 OAJ31026.1 - 1.1e-62 211.4 0.2 2.2e-62 210.5 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ31026.1 - 3.4e-24 85.1 3.6 4.9e-24 84.6 2.4 2.0 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 OAJ31026.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 OAJ31026.1 - 0.011 15.0 0.6 0.017 14.3 0.1 1.5 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 OAJ31026.1 - 0.014 15.3 0.6 0.025 14.5 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 OAJ31026.1 - 0.024 14.0 0.2 0.04 13.3 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 OAJ31026.1 - 0.029 14.7 0.1 0.11 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 OAJ31026.1 - 0.053 14.0 0.0 0.28 11.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 OAJ31026.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 OAJ31026.1 - 0.084 13.2 0.6 0.34 11.2 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ31026.1 - 0.19 12.1 0.0 0.41 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MAP65_ASE1 PF03999.12 OAJ31027.1 - 1.5e-41 142.8 1.0 1.5e-39 136.2 0.1 2.1 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Apolipoprotein PF01442.18 OAJ31027.1 - 0.26 11.1 12.8 0.36 10.7 10.4 2.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TFIIA PF03153.13 OAJ31027.1 - 7.6 6.4 13.4 0.087 12.8 4.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Asp PF00026.23 OAJ31028.1 - 1.6e-46 159.2 0.4 5.1e-46 157.5 0.4 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ31028.1 - 4e-07 30.4 0.5 0.015 15.5 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ31028.1 - 0.00063 20.3 0.4 0.25 12.0 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ31028.1 - 0.0018 18.8 0.1 0.055 14.0 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 OAJ31028.1 - 0.0067 16.2 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Reg_prop PF07494.11 OAJ31028.1 - 0.14 12.4 0.9 43 4.8 0.0 3.6 3 0 0 3 3 3 0 Two component regulator propeller DNA_pol3_delta2 PF13177.6 OAJ31029.1 - 2.8e-11 43.5 0.0 7.7e-11 42.0 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 OAJ31029.1 - 9.1e-05 22.9 0.2 0.00029 21.3 0.2 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ31029.1 - 0.0066 16.9 0.1 0.044 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 OAJ31029.1 - 0.007 16.5 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 OAJ31029.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 OAJ31029.1 - 0.014 15.7 0.1 0.06 13.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 OAJ31029.1 - 0.026 14.9 0.0 0.075 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DUF1254 PF06863.12 OAJ31029.1 - 0.028 14.5 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) Rep_fac_C PF08542.11 OAJ31029.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Replication factor C C-terminal domain RuvB_N PF05496.12 OAJ31029.1 - 0.055 13.2 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Tti2 PF10521.9 OAJ31030.1 - 2.8e-16 59.9 0.0 9.4e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 Tti2 family Complex1_LYR PF05347.15 OAJ31031.1 - 2.8e-05 24.1 0.6 5.4e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Rubis-subs-bind PF09273.11 OAJ31032.1 - 6.3e-13 49.5 0.0 1.3e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 OAJ31032.1 - 1.3e-12 48.4 0.0 3e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 SET domain CENP-B_dimeris PF09026.10 OAJ31032.1 - 0.27 11.6 4.7 0.56 10.6 4.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EAF PF09816.9 OAJ31033.1 - 1.7e-14 54.0 0.0 5.2e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NOA36 PF06524.12 OAJ31033.1 - 5.1e-05 22.7 5.0 5.1e-05 22.7 5.0 3.0 2 1 0 2 2 2 1 NOA36 protein Nop14 PF04147.12 OAJ31033.1 - 0.053 11.7 44.7 0.009 14.3 8.8 2.0 2 0 0 2 2 2 0 Nop14-like family ALMT PF11744.8 OAJ31033.1 - 3.3 6.4 3.7 5 5.8 3.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter BSP_II PF05432.11 OAJ31033.1 - 3.5 7.2 37.9 0.53 9.9 7.0 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4505 PF14956.6 OAJ31034.1 - 8.6e-31 107.0 0.0 2.3e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4505) Axin_b-cat_bind PF08833.10 OAJ31034.1 - 0.69 10.1 2.7 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Axin beta-catenin binding domain Asp PF00026.23 OAJ31035.1 - 5.5e-45 154.2 0.1 2.9e-44 151.8 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ31035.1 - 2.2e-06 28.0 2.5 0.031 14.5 1.1 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ31035.1 - 7.1e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal GET2 PF08690.10 OAJ31036.1 - 0.23 11.1 0.9 0.45 10.1 0.9 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 tRNA-synt_1e PF01406.19 OAJ31037.1 - 9.2e-122 406.1 0.0 3.1e-73 246.8 0.2 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 OAJ31037.1 - 3.3e-07 29.4 0.8 0.00022 20.1 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 OAJ31037.1 - 6.8e-05 23.3 0.2 0.00042 20.7 0.0 2.5 2 0 0 2 2 2 1 DALR domain tRNA-synt_1 PF00133.22 OAJ31037.1 - 0.00013 20.4 0.3 0.0027 16.1 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 OAJ31037.1 - 0.0022 17.0 0.3 0.6 9.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 OAJ31037.1 - 0.022 13.7 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) Rab5ip PF07019.12 OAJ31038.1 - 5.6e-15 55.7 5.0 7.2e-15 55.4 5.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) RabGAP-TBC PF00566.18 OAJ31039.1 - 2.2e-26 92.9 0.0 9.7e-26 90.8 0.0 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain SNARE PF05739.19 OAJ31040.1 - 5.1e-10 39.2 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ31040.1 - 0.0002 21.1 10.1 0.0002 21.1 10.1 2.1 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 OAJ31040.1 - 0.0063 16.9 6.3 0.16 12.3 0.8 2.4 2 0 0 2 2 2 2 Syntaxin-like protein MCPsignal PF00015.21 OAJ31040.1 - 0.008 16.0 5.1 0.027 14.3 1.2 2.5 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2797 PF10977.8 OAJ31040.1 - 0.25 11.2 1.9 0.33 10.8 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) DUF1043 PF06295.12 OAJ31040.1 - 0.48 10.4 4.7 11 6.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) DUF1676 PF07898.13 OAJ31040.1 - 0.78 9.8 2.6 0.92 9.5 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) Diphthamide_syn PF01866.17 OAJ31041.1 - 9.7e-73 245.2 0.0 1.6e-36 126.3 0.0 3.4 2 1 0 2 2 2 2 Putative diphthamide synthesis protein zf-UBR PF02207.20 OAJ31042.1 - 5.7e-15 55.2 14.8 5.7e-15 55.2 14.8 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 OAJ31042.1 - 5.5e-09 35.7 0.1 2.2e-08 33.8 0.1 2.1 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 OAJ31042.1 - 0.00096 18.7 0.1 0.0027 17.2 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II elongation factor ELL ANAPC4_WD40 PF12894.7 OAJ31043.1 - 4.2e-06 27.0 0.0 0.98 9.8 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF100_C PF13299.6 OAJ31043.1 - 0.0008 19.6 2.0 0.0017 18.6 2.0 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal WD40 PF00400.32 OAJ31043.1 - 0.0018 19.1 0.6 11 7.0 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 OAJ31043.1 - 0.14 10.9 0.0 3.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like CDC45 PF02724.14 OAJ31043.1 - 0.33 9.2 8.7 0.47 8.7 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 OAJ31043.1 - 1 8.7 16.0 1.5 8.2 16.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 OAJ31043.1 - 3.8 6.7 14.9 6.1 6.1 14.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 OAJ31043.1 - 4.3 5.4 14.8 5.7 5.0 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family Rotamase PF00639.21 OAJ31044.1 - 1e-16 61.7 0.0 2e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 OAJ31044.1 - 1.7e-16 60.8 0.0 2.3e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 OAJ31044.1 - 3.4e-07 30.2 3.0 8.5e-07 29.0 1.3 2.1 2 0 0 2 2 2 1 WW domain Yae1_N PF09811.9 OAJ31045.1 - 3.2e-10 39.5 0.4 3.2e-10 39.5 0.4 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF4246 PF14033.6 OAJ31046.1 - 6.8e-121 404.5 0.0 8.1e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-Fe_Oxy_2 PF10014.9 OAJ31046.1 - 0.064 13.1 0.0 0.48 10.2 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe dioxygenase PGAP1 PF07819.13 OAJ31047.1 - 1.8e-61 207.8 0.0 2.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 OAJ31047.1 - 0.027 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ31047.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 OAJ31047.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 RRM_1 PF00076.22 OAJ31048.1 - 0.0059 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ31048.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif zf-RRN7 PF11781.8 OAJ31049.1 - 0.0022 17.6 0.1 0.0049 16.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 OAJ31049.1 - 0.027 14.7 0.2 0.055 13.8 0.2 1.5 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Med5 PF08689.10 OAJ31049.1 - 0.17 9.6 3.6 0.22 9.3 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 Peptidase_M43 PF05572.13 OAJ31050.1 - 5.2e-19 68.7 1.8 6e-19 68.5 0.7 1.7 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 OAJ31050.1 - 4.6e-07 30.4 0.2 1.7e-05 25.3 0.0 2.3 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ31050.1 - 6e-05 23.3 5.8 8.5e-05 22.8 5.8 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 OAJ31050.1 - 0.0042 16.9 0.0 0.0057 16.5 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 OAJ31050.1 - 0.029 14.0 5.7 0.05 13.2 5.3 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like GTP_EFTU PF00009.27 OAJ31051.1 - 1.5e-55 187.8 0.1 2.5e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 OAJ31051.1 - 2.1e-13 50.1 0.0 4.5e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ31051.1 - 2.1e-08 34.2 0.0 4.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ31051.1 - 0.0033 17.8 0.0 0.015 15.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 OAJ31051.1 - 0.018 14.8 0.1 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 OAJ31051.1 - 0.02 14.9 0.0 0.066 13.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sec63 PF02889.16 OAJ31052.1 - 5e-68 229.0 0.0 7.6e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 OAJ31052.1 - 4e-38 130.9 1.2 2.5e-25 89.2 0.1 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 OAJ31052.1 - 7e-15 55.4 0.0 1.1e-10 41.8 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ31052.1 - 4.4e-07 30.2 0.0 0.0028 18.0 0.0 4.4 4 2 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 OAJ31052.1 - 0.00032 21.0 0.2 0.03 14.6 0.1 3.6 3 1 0 3 3 3 1 AAA domain Helicase_PWI PF18149.1 OAJ31052.1 - 0.0057 16.8 0.0 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal helicase PWI domain T2SSE PF00437.20 OAJ31052.1 - 0.0073 15.4 0.0 0.77 8.8 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 OAJ31052.1 - 0.052 13.9 0.2 12 6.3 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain UvrD-helicase PF00580.21 OAJ31052.1 - 0.11 12.0 0.2 12 5.3 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF3759 PF12585.8 OAJ31053.1 - 4.9e-41 138.7 10.1 5.4e-41 138.5 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Borrelia_P83 PF05262.11 OAJ31054.1 - 0.063 11.8 18.6 0.11 11.0 18.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_12 PF13424.6 OAJ31056.1 - 0.12 12.6 0.1 0.12 12.6 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ31056.1 - 0.15 12.0 1.1 4.4 7.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ31056.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.18 OAJ31057.1 - 4.2e-06 26.8 11.3 6.8e-06 26.1 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YL1 PF05764.13 OAJ31057.1 - 1.9 8.6 5.5 2 8.5 2.6 2.0 2 0 0 2 2 2 0 YL1 nuclear protein ATP-synt_E PF05680.12 OAJ31058.1 - 6.3e-21 74.5 0.1 7e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain LdpA_C PF12617.8 OAJ31058.1 - 0.15 11.7 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal NAD_Gly3P_dh_C PF07479.14 OAJ31059.1 - 8.8e-47 159.0 0.1 2e-46 157.8 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 OAJ31059.1 - 9.3e-47 158.9 0.0 3.5e-46 157.0 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 OAJ31059.1 - 1.9e-05 25.2 0.7 0.00056 20.4 0.7 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 OAJ31059.1 - 0.0051 16.4 0.4 0.58 9.7 0.0 2.4 1 1 1 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain Complex1_30kDa PF00329.19 OAJ31060.1 - 6.1e-46 156.0 0.0 8.3e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF1958 PF09211.10 OAJ31061.1 - 0.056 13.8 0.0 0.08 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1958) Bot1p PF12298.8 OAJ31062.1 - 0.094 12.9 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Perilipin PF03036.16 OAJ31063.1 - 1.2e-06 27.9 0.6 0.00027 20.1 0.0 2.6 1 1 2 3 3 3 2 Perilipin family ApoLp-III PF07464.11 OAJ31063.1 - 0.16 12.1 2.2 0.26 11.4 1.2 1.9 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.18 OAJ31063.1 - 0.19 11.6 2.5 0.44 10.4 2.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 OAJ31063.1 - 0.37 11.4 1.7 0.74 10.4 1.0 1.8 2 0 0 2 2 2 0 YtxH-like protein Pkinase PF00069.25 OAJ31064.1 - 7.1e-35 120.6 0.0 1.8e-34 119.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31064.1 - 1.5e-19 70.3 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ31064.1 - 0.28 9.9 0.0 0.47 9.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_47 PF01532.20 OAJ31065.1 - 9.1e-118 394.0 0.1 1.1e-117 393.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Na_H_Exchanger PF00999.21 OAJ31066.1 - 1.4e-65 221.6 22.8 1.8e-65 221.2 22.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3811 PF11656.8 OAJ31066.1 - 0.031 14.7 1.0 0.088 13.2 1.0 1.7 1 0 0 1 1 1 0 YjbD family (DUF3811) YrhC PF14143.6 OAJ31066.1 - 0.11 12.6 1.1 0.38 10.9 1.1 1.9 1 0 0 1 1 1 0 YrhC-like protein Pro_isomerase PF00160.21 OAJ31068.1 - 1.4e-42 145.7 0.3 9.1e-42 143.0 0.3 1.9 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SCP2 PF02036.17 OAJ31069.1 - 6.4e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 OAJ31069.1 - 0.0029 17.9 0.0 0.0045 17.3 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 OAJ31069.1 - 0.0091 16.4 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 Sterol carrier protein domain SCP_3 PF17844.1 OAJ31069.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog Methyltransf_16 PF10294.9 OAJ31070.1 - 2.1e-08 34.1 0.0 2.8e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase ESSS PF10183.9 OAJ31070.1 - 0.12 12.6 0.2 0.37 11.0 0.2 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CRC_subunit PF08624.10 OAJ31071.1 - 9.8e-39 132.9 0.0 1.7e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TFIIA PF03153.13 OAJ31071.1 - 0.23 11.4 24.0 0.35 10.8 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 OAJ31073.1 - 1.5e-05 24.5 0.0 0.066 12.7 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase AAA_6 PF12774.7 OAJ31074.1 - 2.8e-130 434.1 0.0 1.5e-129 431.7 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 OAJ31074.1 - 5.5e-115 384.6 6.1 5.5e-115 384.6 6.1 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 OAJ31074.1 - 3.1e-109 366.2 11.7 3.1e-109 366.2 11.7 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 OAJ31074.1 - 1.7e-42 145.0 0.0 3.5e-36 124.4 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_8 PF12780.7 OAJ31074.1 - 1.1e-40 139.6 0.0 4.3e-40 137.7 0.0 2.1 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_5 PF07728.14 OAJ31074.1 - 1.3e-27 96.5 0.0 4.3e-13 49.4 0.0 6.1 6 0 0 6 6 6 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 OAJ31074.1 - 1e-14 54.7 0.0 3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 OAJ31074.1 - 7e-14 52.3 0.3 0.0055 17.0 0.0 5.8 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 OAJ31074.1 - 7.5e-14 52.3 0.0 0.0068 16.8 0.0 5.3 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ31074.1 - 4.2e-10 40.3 1.8 0.073 13.5 0.2 6.5 5 1 0 6 6 5 2 AAA ATPase domain AAA_33 PF13671.6 OAJ31074.1 - 1.3e-09 38.3 0.0 0.12 12.6 0.0 4.9 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 OAJ31074.1 - 1.4e-07 32.2 0.0 1.5 9.4 0.0 4.9 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 OAJ31074.1 - 3.3e-07 29.6 0.0 0.0053 15.9 0.0 3.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_30 PF13604.6 OAJ31074.1 - 6e-06 26.1 0.8 4.3 7.0 0.0 4.7 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 OAJ31074.1 - 4.7e-05 22.9 2.9 0.59 9.5 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 OAJ31074.1 - 0.00021 21.1 0.7 0.71 9.6 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_19 PF13245.6 OAJ31074.1 - 0.00066 20.0 8.5 0.28 11.5 0.0 5.6 6 1 1 7 7 5 1 AAA domain AAA_lid_1 PF17857.1 OAJ31074.1 - 0.00069 19.8 0.0 0.0036 17.5 0.0 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 OAJ31074.1 - 0.0034 17.1 0.1 9.2 6.1 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rad17 PF03215.15 OAJ31074.1 - 0.0035 17.3 0.1 23 4.8 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_24 PF13479.6 OAJ31074.1 - 0.0074 16.0 0.3 20 4.8 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 OAJ31074.1 - 0.012 15.1 0.0 0.54 9.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 OAJ31074.1 - 0.017 15.5 0.0 18 5.7 0.0 4.3 4 0 0 4 4 4 0 RNA helicase AAA_11 PF13086.6 OAJ31074.1 - 0.021 14.6 1.9 1.2 8.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 OAJ31074.1 - 0.023 14.1 0.0 18 4.6 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 OAJ31074.1 - 0.027 15.0 3.9 62 4.1 0.0 5.1 5 0 0 5 5 4 0 ABC transporter RuvB_N PF05496.12 OAJ31074.1 - 0.042 13.6 0.2 4.2 7.1 0.0 3.6 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 OAJ31074.1 - 0.41 10.2 1.3 51 3.4 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF148 PF02520.17 OAJ31074.1 - 4.7 7.4 8.2 3.7 7.7 2.5 3.7 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF1664 PF07889.12 OAJ31074.1 - 5 7.2 5.8 19 5.3 0.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1749 PF08538.10 OAJ31075.1 - 0.00041 19.5 0.0 0.00059 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 OAJ31075.1 - 0.033 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 OAJ31075.1 - 0.051 13.1 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 OAJ31075.1 - 0.15 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 OAJ31075.1 - 0.15 11.3 0.0 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zf-rbx1 PF12678.7 OAJ31076.1 - 2e-25 88.8 12.4 3.2e-25 88.2 12.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ31076.1 - 1.4e-17 63.5 11.9 1.9e-17 63.1 11.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 OAJ31076.1 - 1e-06 29.0 16.7 9.6e-05 22.6 16.7 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ31076.1 - 1.5e-05 24.8 3.0 1.5e-05 24.8 3.0 2.4 1 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ31076.1 - 0.00033 20.5 10.7 0.0036 17.1 10.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ31076.1 - 0.0097 15.8 10.0 0.097 12.6 3.6 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ31076.1 - 0.17 11.5 14.6 0.063 12.9 4.4 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 OAJ31076.1 - 3 7.9 11.7 0.8 9.8 7.7 2.2 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.8 OAJ31076.1 - 3.2 8.0 16.5 0.2 11.8 9.3 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 OAJ31076.1 - 3.2 7.6 20.4 49 3.8 17.3 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 OAJ31076.1 - 4 7.5 11.9 20 5.2 11.9 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FHA PF00498.26 OAJ31077.1 - 2.2e-14 53.6 0.1 4e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 OAJ31077.1 - 4.6e-11 42.3 12.4 7.3e-11 41.6 12.4 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 OAJ31077.1 - 5.4e-07 29.9 13.6 8.1e-07 29.3 13.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ31077.1 - 0.0067 16.2 13.9 0.011 15.6 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 OAJ31077.1 - 0.013 15.7 8.9 0.025 14.8 8.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ31077.1 - 0.023 14.8 5.2 0.038 14.0 5.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 OAJ31077.1 - 0.041 13.7 13.0 0.064 13.1 13.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ31077.1 - 0.057 13.4 11.8 0.095 12.7 11.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Yop-YscD_cpl PF16697.5 OAJ31077.1 - 0.14 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Zn_ribbon_17 PF17120.5 OAJ31077.1 - 1.6 8.4 8.7 2.7 7.7 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 OAJ31077.1 - 2.5 8.1 8.1 4.6 7.2 8.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 OAJ31077.1 - 5.1 7.2 12.8 10 6.2 12.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger RPAP1_N PF08621.10 OAJ31078.1 - 2.3e-07 30.5 1.5 4.8e-07 29.4 1.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 OAJ31078.1 - 0.011 15.8 1.6 0.063 13.4 1.6 2.3 1 1 0 1 1 1 0 RPAP1-like, C-terminal YdaT_toxin PF06254.11 OAJ31078.1 - 0.12 13.0 0.1 14 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative bacterial toxin ydaT FlxA PF14282.6 OAJ31078.1 - 1.7 8.6 6.4 7.1 6.7 6.4 2.0 1 0 0 1 1 1 0 FlxA-like protein Cation_efflux PF01545.21 OAJ31079.1 - 3.8e-49 167.1 12.6 9.4e-49 165.9 12.6 1.6 1 1 0 1 1 1 1 Cation efflux family YL1 PF05764.13 OAJ31081.1 - 4.7 7.3 11.2 0.33 11.0 5.2 2.0 1 1 0 2 2 2 0 YL1 nuclear protein DDE_3 PF13358.6 OAJ31082.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 OAJ31082.1 - 2.8e-07 30.1 0.6 2.6e-05 23.8 0.0 3.0 3 0 0 3 3 3 1 Winged helix-turn helix HTH_32 PF13565.6 OAJ31082.1 - 0.0023 18.5 0.6 0.011 16.3 0.6 2.2 1 1 0 1 1 1 1 Homeodomain-like domain DDE_1 PF03184.19 OAJ31082.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Ham1p_like PF01725.16 OAJ31083.1 - 2e-59 200.7 0.0 2.2e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Histone PF00125.24 OAJ31084.1 - 1.6e-22 80.3 0.2 2.1e-22 79.9 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ31084.1 - 5e-07 29.9 0.1 9.2e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 OAJ31084.1 - 0.00044 20.7 0.0 0.0007 20.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 OAJ31084.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 OAJ31084.1 - 0.066 13.2 0.1 0.077 13.0 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein RP-C PF03428.13 OAJ31084.1 - 0.099 12.3 0.2 0.26 10.9 0.2 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Ada3 PF10198.9 OAJ31085.1 - 7.2e-26 90.9 0.4 5.7e-25 88.0 0.0 2.5 2 1 0 2 2 2 1 Histone acetyltransferases subunit 3 Histone_H2A_C PF16211.5 OAJ31087.1 - 1.7e-18 66.1 0.7 3.4e-18 65.1 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 OAJ31087.1 - 1.3e-16 61.1 0.0 1.8e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ31087.1 - 1.1e-05 25.6 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Lactamase_B_2 PF12706.7 OAJ31088.1 - 1.9e-09 37.3 0.1 0.0001 21.9 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 OAJ31088.1 - 2.5e-09 36.7 0.0 5.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 OAJ31088.1 - 0.014 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PIF1 PF05970.14 OAJ31089.1 - 1.8e-103 346.5 0.0 2.5e-103 346.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 OAJ31089.1 - 1.5e-58 198.2 0.1 3.1e-58 197.2 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 OAJ31089.1 - 3.1e-09 36.9 0.2 5.5e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 OAJ31089.1 - 8.8e-08 30.6 0.0 4.4e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 OAJ31089.1 - 0.0023 17.7 0.0 0.0058 16.4 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 OAJ31089.1 - 0.029 14.8 0.0 0.17 12.3 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 OAJ31089.1 - 0.029 13.4 0.0 0.065 12.3 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 OAJ31089.1 - 0.03 14.7 0.0 0.098 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DDE_Tnp_4 PF13359.6 OAJ31091.1 - 9.6e-23 80.6 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.6 OAJ31092.1 - 9e-05 22.8 0.2 9e-05 22.8 0.2 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Neur_chan_memb PF02932.16 OAJ31092.1 - 1.6 8.7 3.3 1 9.4 0.8 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region She9_MDM33 PF05546.11 OAJ31093.1 - 0.028 14.2 0.4 0.2 11.5 0.3 2.0 2 0 0 2 2 2 0 She9 / Mdm33 family DUF2884 PF11101.8 OAJ31093.1 - 0.18 11.3 0.2 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Mating_N PF12731.7 OAJ31093.1 - 0.23 11.6 2.5 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 CRAL_TRIO PF00650.20 OAJ31094.1 - 6e-29 100.8 0.0 9.1e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ31094.1 - 2.4e-08 34.2 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ31094.1 - 1.8e-07 31.2 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LSM PF01423.22 OAJ31095.1 - 1.1e-15 57.1 0.0 1.9e-15 56.3 0.0 1.4 2 0 0 2 2 2 1 LSM domain DUF3510 PF12022.8 OAJ31095.1 - 0.0044 17.4 0.0 0.0053 17.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) GRP PF07172.11 OAJ31095.1 - 2.6 8.8 28.4 3.8 8.3 28.4 1.2 1 0 0 1 1 1 0 Glycine rich protein family MFS_1 PF07690.16 OAJ31096.1 - 2.8e-16 59.4 43.0 2.8e-16 59.4 43.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_transf_8 PF01501.20 OAJ31097.1 - 1.2e-18 67.7 0.0 9.8e-16 58.1 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 OAJ31097.1 - 0.038 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Thiol_cytolysin PF01289.19 OAJ31097.1 - 0.2 10.5 0.0 0.4 9.5 0.0 1.4 1 0 0 1 1 1 0 Thiol-activated cytolysin PITH PF06201.13 OAJ31098.1 - 1.2e-35 122.9 0.0 1.5e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain ATP-synt PF00231.19 OAJ31099.1 - 5.3e-75 252.7 2.7 6e-75 252.5 2.7 1.0 1 0 0 1 1 1 1 ATP synthase Bac_rhamnosid_N PF08531.10 OAJ31099.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain eIF-5_eIF-2B PF01873.17 OAJ31100.1 - 5.6e-40 135.9 0.3 9.1e-40 135.2 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 OAJ31100.1 - 0.00051 19.5 0.2 0.00086 18.8 0.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Bclt PF15318.6 OAJ31100.1 - 0.25 11.2 5.3 0.089 12.6 2.3 1.9 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis Arc_trans_TRASH PF08394.10 OAJ31100.1 - 8.1 6.9 12.2 0.54 10.6 0.2 2.8 2 1 1 3 3 3 0 Archaeal TRASH domain Pyrid_ox_like PF16242.5 OAJ31101.1 - 2.5e-29 101.8 0.2 4.1e-29 101.1 0.2 1.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 OAJ31101.1 - 3.4e-11 43.2 0.0 1.6e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF374 PF04028.13 OAJ31101.1 - 0.026 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Nodulin_late PF07127.11 OAJ31102.1 - 0.2 12.0 2.5 2.2 8.7 0.1 2.6 3 0 0 3 3 3 0 Late nodulin protein CDT1_C PF16679.5 OAJ31103.1 - 2.3e-14 53.6 2.4 9.4e-12 45.2 0.1 3.3 2 1 0 2 2 2 2 DNA replication factor Cdt1 C-terminal domain Ribosomal_L21e PF01157.18 OAJ31104.1 - 1.7e-45 153.0 2.0 1.7e-45 153.0 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e TRAM PF01938.20 OAJ31104.1 - 0.022 14.7 0.6 7.3 6.7 0.2 2.4 2 0 0 2 2 2 0 TRAM domain TRAP-gamma PF07074.12 OAJ31104.1 - 0.12 11.9 0.4 0.16 11.5 0.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PepSY_TM PF03929.16 OAJ31105.1 - 0.018 14.7 0.9 0.018 14.7 0.9 1.6 1 1 0 1 1 1 0 PepSY-associated TM region DUF1072 PF06380.11 OAJ31105.1 - 1.4 8.9 5.8 2.5 8.0 2.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) RasGEF PF00617.19 OAJ31106.1 - 1.4e-40 139.4 0.0 2.9e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ31106.1 - 7.2e-10 39.0 0.4 1.6e-09 37.9 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif S4 PF01479.25 OAJ31107.1 - 4.9e-11 42.2 1.3 4.9e-11 42.2 1.3 2.8 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 OAJ31107.1 - 2.1e-06 28.6 0.3 5e-06 27.3 0.1 1.7 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Shugoshin_N PF07558.11 OAJ31109.1 - 0.034 14.0 0.3 0.097 12.6 0.3 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Cnn_1N PF07989.11 OAJ31109.1 - 2.2 8.5 10.0 1 9.6 1.0 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Atg14 PF10186.9 OAJ31109.1 - 4.9 6.1 9.8 0.41 9.7 3.6 2.2 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 OAJ31109.1 - 7.9 6.5 21.7 0.8 9.7 3.0 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_trans PF04082.18 OAJ31110.1 - 1e-13 50.9 0.2 2.6e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ31110.1 - 2.1e-07 30.9 9.9 3.2e-07 30.3 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3074 PF11274.8 OAJ31111.1 - 1.8e-45 155.2 0.0 2.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ORC4_C PF14629.6 OAJ31112.1 - 1e-26 93.7 0.0 2.7e-26 92.3 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 OAJ31112.1 - 4.7e-07 30.3 0.3 4.7e-07 30.3 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 OAJ31112.1 - 0.0067 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) YL1 PF05764.13 OAJ31112.1 - 0.0075 16.4 6.6 0.0075 16.4 6.6 2.4 2 0 0 2 2 2 1 YL1 nuclear protein Apt1 PF10351.9 OAJ31112.1 - 0.06 12.2 0.9 0.26 10.1 0.9 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDC45 PF02724.14 OAJ31112.1 - 1.5 7.0 14.6 0.27 9.5 5.9 2.3 2 0 0 2 2 2 0 CDC45-like protein Thioredoxin PF00085.20 OAJ31113.1 - 8.7e-05 22.5 0.1 0.00014 21.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3417 PF11897.8 OAJ31113.1 - 0.019 15.4 0.4 0.032 14.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DIM1 PF02966.16 OAJ31113.1 - 0.1 12.4 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 HOOK PF05622.12 OAJ31114.1 - 7.5e-50 169.8 69.0 7.5e-50 169.8 69.0 3.2 1 1 1 2 2 2 1 HOOK protein BLOC1_2 PF10046.9 OAJ31114.1 - 0.0027 17.9 9.4 0.0027 17.9 9.4 6.7 5 2 2 7 7 7 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 OAJ31114.1 - 0.24 10.9 89.8 0.02 14.5 11.9 5.1 3 2 1 5 5 5 0 Intermediate filament protein Ribosomal_L7Ae PF01248.26 OAJ31116.1 - 6.1e-26 90.0 0.1 7.8e-26 89.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 OAJ31116.1 - 0.0009 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 OAJ31116.1 - 0.004 17.2 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Paf67 PF10255.9 OAJ31117.1 - 4.2e-168 559.5 0.0 7e-168 558.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 OAJ31117.1 - 0.0063 16.5 0.0 0.0063 16.5 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ31117.1 - 0.0083 15.9 0.0 0.068 13.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DEAD PF00270.29 OAJ31119.1 - 2.8e-31 108.7 0.0 8.3e-31 107.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ31119.1 - 8.3e-25 87.3 0.0 2.2e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UTP25 PF06862.12 OAJ31119.1 - 0.018 13.9 0.0 1.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 PLDc PF00614.22 OAJ31120.1 - 1.1e-15 57.1 0.2 7.5e-07 29.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 OAJ31120.1 - 2.6e-12 46.8 0.0 1.1e-06 28.6 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 OAJ31120.1 - 6.7e-09 35.7 0.0 1.9e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 PX domain PH PF00169.29 OAJ31120.1 - 0.084 13.4 0.1 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 PH domain Lactamase_B_2 PF12706.7 OAJ31121.1 - 4.9e-05 22.9 4.3 0.00015 21.3 1.6 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 OAJ31121.1 - 0.04 13.9 0.4 0.14 12.2 0.4 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PXA PF02194.15 OAJ31123.1 - 1.2e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 OAJ31123.1 - 1.1e-12 48.5 0.0 3e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal DUF2273 PF10031.9 OAJ31123.1 - 0.49 10.4 2.0 0.89 9.6 2.0 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) UCH PF00443.29 OAJ31124.1 - 4.9e-42 144.2 0.0 2.1e-41 142.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ31124.1 - 2.4e-20 73.4 0.1 1.6e-10 41.1 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ31124.1 - 1.9e-08 34.5 1.0 1.9e-08 34.5 1.0 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein PBP1_TM PF14812.6 OAJ31124.1 - 4.5 7.7 14.8 1 9.8 6.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 OAJ31124.1 - 4.6 7.5 11.5 10 6.4 6.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 OAJ31124.1 - 6 6.6 7.3 0.82 9.4 1.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RabGAP-TBC PF00566.18 OAJ31125.1 - 4e-43 147.6 0.2 5.4e-43 147.2 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 OAJ31126.1 - 0.0013 18.8 1.2 0.0017 18.4 1.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc29 PF17082.5 OAJ31126.1 - 0.0092 15.9 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 Cnn_1N PF07989.11 OAJ31126.1 - 0.016 15.3 3.1 0.016 15.3 3.1 1.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 OAJ31126.1 - 0.021 15.4 3.2 0.035 14.6 3.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3410 PF11890.8 OAJ31126.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DivIC PF04977.15 OAJ31126.1 - 0.086 12.6 4.9 0.13 12.1 4.1 1.6 1 1 1 2 2 2 0 Septum formation initiator VGPC1_C PF16799.5 OAJ31126.1 - 0.16 12.0 1.9 0.26 11.3 0.2 2.0 1 1 1 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 HMG_box PF00505.19 OAJ31127.1 - 1.6e-11 44.5 0.3 2.8e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ31127.1 - 2.7e-10 40.7 0.3 5.5e-10 39.7 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain DSPc PF00782.20 OAJ31128.1 - 2.6e-16 59.7 0.0 1.1e-14 54.3 0.2 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ31128.1 - 0.027 14.0 0.1 0.046 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase WD40 PF00400.32 OAJ31129.1 - 4.1e-07 30.6 4.4 0.11 13.4 0.3 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat YL1 PF05764.13 OAJ31129.1 - 5.3 7.1 27.5 2 8.5 15.1 2.7 3 0 0 3 3 3 0 YL1 nuclear protein TPR_8 PF13181.6 OAJ31130.1 - 0.003 17.6 0.0 0.027 14.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC5 PF12862.7 OAJ31130.1 - 0.1 12.7 0.3 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 OAJ31130.1 - 0.16 12.3 5.3 0.24 11.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SNARE_assoc PF09335.11 OAJ31132.1 - 1.1e-13 51.8 1.3 2.3e-13 50.7 1.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PUF PF00806.19 OAJ31133.1 - 1.3e-14 52.9 0.9 2.9e-07 29.8 0.0 4.8 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat DUF676 PF05057.14 OAJ31134.1 - 0.00019 21.1 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 OAJ31134.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 OAJ31134.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 OAJ31134.1 - 1.4 8.5 10.2 0.1 12.2 0.8 3.3 3 1 0 3 3 3 0 alpha/beta hydrolase fold CAP_GLY PF01302.25 OAJ31136.1 - 3.5e-19 68.6 0.1 8.1e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 OAJ31136.1 - 4.5e-06 26.3 6.8 0.019 14.7 0.5 4.9 3 2 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 OAJ31136.1 - 0.0014 19.0 7.4 1.8 9.1 0.0 4.8 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) FRG1 PF06229.12 OAJ31137.1 - 2.9e-21 76.1 4.2 3.1e-08 33.5 0.1 3.3 3 0 0 3 3 3 3 FRG1-like domain Fascin PF06268.13 OAJ31137.1 - 2.3e-06 27.8 0.0 0.002 18.3 0.0 2.4 2 0 0 2 2 2 2 Fascin domain DUF4126 PF13548.6 OAJ31137.1 - 0.093 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) DNase_NucA_NucB PF14040.6 OAJ31138.1 - 1.6e-25 89.7 2.1 2.1e-25 89.3 2.1 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Suppressor_APC PF11414.8 OAJ31139.1 - 0.18 11.9 1.9 0.54 10.4 1.9 1.8 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Glypican PF01153.19 OAJ31139.1 - 0.31 9.8 2.3 0.69 8.7 2.3 1.5 1 0 0 1 1 1 0 Glypican DUF4149 PF13664.6 OAJ31140.1 - 7.2e-20 71.2 3.7 7.2e-20 71.2 3.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Hva1_TUDOR PF11160.8 OAJ31141.1 - 2.6e-13 49.9 0.1 2.6e-13 49.9 0.1 3.1 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain GREB1 PF15782.5 OAJ31141.1 - 9.5 3.2 25.6 10 3.0 25.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FGGY_N PF00370.21 OAJ31143.1 - 8.9e-73 244.9 0.1 1.3e-72 244.3 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 OAJ31143.1 - 7.5e-68 228.2 2.6 2.7e-67 226.3 1.4 2.2 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain ThrE PF06738.12 OAJ31144.1 - 2.2e-55 187.6 4.7 2.2e-55 187.6 4.7 2.5 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ31144.1 - 8.6e-08 32.4 7.7 8.6e-08 32.4 7.7 2.5 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE FA_desaturase PF00487.24 OAJ31144.1 - 0.14 11.9 5.2 0.15 11.8 3.1 2.2 2 0 0 2 2 2 0 Fatty acid desaturase ABC_tran PF00005.27 OAJ31145.1 - 4.1e-46 156.9 0.0 3.8e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ31145.1 - 4.8e-45 154.3 18.9 1.3e-23 84.1 11.7 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.6 OAJ31145.1 - 6.3e-11 43.2 1.6 5.1e-06 27.1 0.5 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 OAJ31145.1 - 5.5e-09 35.8 6.6 0.0033 16.9 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 OAJ31145.1 - 2.1e-08 34.3 2.0 0.023 14.5 0.3 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ31145.1 - 5.4e-08 32.5 1.6 0.0046 16.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ31145.1 - 8.3e-07 29.1 0.2 0.02 14.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 OAJ31145.1 - 3.4e-06 27.1 0.8 0.012 15.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 OAJ31145.1 - 5.4e-06 26.9 0.4 0.19 12.1 0.1 3.3 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 OAJ31145.1 - 4.4e-05 22.7 0.2 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_15 PF13175.6 OAJ31145.1 - 4.4e-05 23.3 2.9 0.00095 19.0 0.3 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 OAJ31145.1 - 9.7e-05 21.7 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 OAJ31145.1 - 0.00033 21.0 0.2 2 8.7 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 OAJ31145.1 - 0.0004 20.1 0.5 2.8 7.6 0.1 3.5 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 OAJ31145.1 - 0.00059 20.0 1.5 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 OAJ31145.1 - 0.0015 18.7 0.6 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 OAJ31145.1 - 0.0016 18.1 0.1 0.0055 16.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 OAJ31145.1 - 0.0018 18.3 6.3 0.39 10.8 0.1 2.6 3 0 0 3 3 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 OAJ31145.1 - 0.0053 16.2 0.3 0.93 8.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 OAJ31145.1 - 0.0079 15.8 0.0 4.1 6.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 OAJ31145.1 - 0.013 14.3 0.7 0.91 8.3 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_7 PF12775.7 OAJ31145.1 - 0.021 14.4 0.3 1 8.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_ATPase PF09818.9 OAJ31145.1 - 0.024 13.5 4.7 3.7 6.2 0.0 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 OAJ31145.1 - 0.052 13.8 0.1 14 5.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ31145.1 - 0.065 13.0 0.1 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 OAJ31145.1 - 0.073 12.7 2.7 3.7 7.1 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 OAJ31145.1 - 0.1 12.5 2.2 12 5.8 0.1 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OAJ31145.1 - 0.11 12.3 0.7 7.1 6.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Septin PF00735.18 OAJ31145.1 - 0.11 11.7 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 OAJ31145.1 - 0.16 12.4 0.2 51 4.3 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAJ31145.1 - 0.19 10.9 0.1 8.9 5.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 OAJ31145.1 - 0.24 11.1 0.2 27 4.4 0.1 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 OAJ31145.1 - 0.44 11.1 2.1 10 6.7 0.3 2.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 OAJ31145.1 - 0.63 10.3 2.6 8.9 6.6 0.1 3.2 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase Maf PF02545.14 OAJ31146.1 - 3.3e-46 157.2 0.0 3.8e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF2236 PF09995.9 OAJ31147.1 - 9e-32 111.1 1.2 2.4e-31 109.7 1.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Metallophos PF00149.28 OAJ31148.1 - 3.5e-10 40.7 0.1 5.5e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3770 PF12603.8 OAJ31148.1 - 0.034 13.7 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) SOG2 PF10428.9 OAJ31149.1 - 0.48 9.6 10.7 0.59 9.3 10.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein GATA PF00320.27 OAJ31150.1 - 0.0045 16.6 3.0 0.0045 16.6 3.0 2.8 3 0 0 3 3 3 1 GATA zinc finger FAM76 PF16046.5 OAJ31150.1 - 0.25 10.6 9.9 0.41 10.0 2.3 2.4 2 0 0 2 2 2 0 FAM76 protein Pro_CA PF00484.19 OAJ31151.1 - 4.2e-37 127.8 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_1 PF00561.20 OAJ31151.1 - 0.036 13.7 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold UDPGT PF00201.18 OAJ31152.1 - 2.9e-12 46.2 0.1 4.4e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF5310 PF17237.2 OAJ31153.1 - 8.5e-19 67.2 5.7 1e-18 66.9 5.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) ADH_zinc_N PF00107.26 OAJ31154.1 - 2.2e-08 34.2 0.0 4.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ31154.1 - 0.0074 16.2 0.0 0.091 12.7 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ArfGap PF01412.18 OAJ31155.1 - 2e-32 111.7 0.7 3.8e-32 110.8 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf ERM PF00769.19 OAJ31155.1 - 8.8 6.1 17.6 14 5.4 17.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GGACT PF06094.12 OAJ31156.1 - 1.7e-10 41.5 0.0 3.5e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like p450 PF00067.22 OAJ31157.1 - 2.2e-71 241.0 0.0 7e-44 150.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Pkinase PF00069.25 OAJ31158.1 - 1.1e-39 136.4 0.1 2.6e-21 76.2 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31158.1 - 2.1e-11 43.6 0.7 1.7e-08 34.1 0.3 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CorA PF01544.18 OAJ31159.1 - 7.6e-19 68.1 3.7 7e-11 42.0 0.2 3.2 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2705 PF10920.8 OAJ31159.1 - 0.075 12.3 0.6 0.12 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) GvpL_GvpF PF06386.11 OAJ31159.1 - 0.15 12.0 4.6 0.46 10.4 4.6 1.8 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3605 PF12239.8 OAJ31160.1 - 5.2e-24 85.3 0.5 9.3e-19 68.3 0.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) SPX PF03105.19 OAJ31160.1 - 0.11 12.4 4.4 0.12 12.2 4.4 1.1 1 0 0 1 1 1 0 SPX domain SUZ PF12752.7 OAJ31160.1 - 0.21 12.4 4.9 0.82 10.5 4.9 2.1 1 1 0 1 1 1 0 SUZ domain MAP65_ASE1 PF03999.12 OAJ31160.1 - 0.24 10.1 2.2 0.3 9.7 2.2 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Dynamin_M PF01031.20 OAJ31161.1 - 3e-12 46.4 0.0 3.1e-12 46.3 0.0 1.0 1 0 0 1 1 1 1 Dynamin central region rOmpB PF12334.8 OAJ31161.1 - 0.07 12.6 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Dynamin_M PF01031.20 OAJ31162.1 - 3.7e-10 39.5 0.0 4.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAJ31163.1 - 5.6e-23 81.8 0.0 7.4e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 OAJ31163.1 - 1.6e-19 70.3 0.0 2.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region vATP-synt_AC39 PF01992.16 OAJ31164.1 - 0.021 14.3 0.1 0.027 14.0 0.1 1.1 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Aminotran_5 PF00266.19 OAJ31165.1 - 8.2e-17 61.2 0.0 2.4e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 OAJ31165.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II GP67 PF17634.2 OAJ31165.1 - 0.79 10.2 16.7 1.5 9.2 16.7 1.4 1 0 0 1 1 1 0 Gene product 67 SDA1 PF05285.12 OAJ31165.1 - 2.2 7.6 10.0 4 6.8 10.0 1.3 1 0 0 1 1 1 0 SDA1 DUF2456 PF10445.9 OAJ31166.1 - 7.6e-18 64.4 1.9 7.6e-18 64.4 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) GTP_EFTU PF00009.27 OAJ31168.1 - 9.3e-65 217.8 0.4 1.4e-64 217.2 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 OAJ31168.1 - 2.5e-31 108.0 0.0 6.1e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 OAJ31168.1 - 2.7e-21 75.4 0.0 6.1e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 OAJ31168.1 - 3.2e-13 49.6 0.0 9.5e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 OAJ31168.1 - 4.9e-12 46.1 0.0 1.5e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 OAJ31168.1 - 0.0012 19.0 0.1 0.0025 17.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase UCR_14kD PF02271.16 OAJ31170.1 - 6.2e-38 128.8 0.6 7.3e-38 128.6 0.6 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Amino_oxidase PF01593.24 OAJ31171.1 - 4.2e-23 82.3 0.4 1.5e-22 80.5 0.4 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ31171.1 - 6.7e-08 32.6 0.1 4.6e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ31171.1 - 5.3e-06 26.3 0.1 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 OAJ31171.1 - 0.0037 16.2 0.0 0.0079 15.1 0.0 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.6 OAJ31171.1 - 0.0051 16.8 0.1 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 OAJ31171.1 - 0.023 14.1 0.0 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ31171.1 - 0.024 13.9 0.0 0.07 12.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 OAJ31171.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family LAS2 PF15792.5 OAJ31172.1 - 0.022 15.3 0.0 0.11 13.1 0.0 2.1 3 0 0 3 3 3 0 Lung adenoma susceptibility protein 2 Cpn60_TCP1 PF00118.24 OAJ31173.1 - 1.9e-159 531.4 3.2 4.6e-104 348.8 0.1 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF1572 PF07609.11 OAJ31173.1 - 0.11 12.2 0.0 1.6 8.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1572) CLASP_N PF12348.8 OAJ31174.1 - 2.9e-17 63.0 0.0 0.00014 21.6 0.0 5.3 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 OAJ31174.1 - 2.1e-13 49.2 14.4 0.00092 19.3 0.1 9.3 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 OAJ31174.1 - 6.4e-11 42.5 4.6 0.039 14.0 0.0 6.5 7 0 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ31174.1 - 1.7e-09 38.0 8.3 0.056 13.8 0.0 7.8 6 2 1 7 7 6 2 HEAT repeats HEAT_EZ PF13513.6 OAJ31174.1 - 6.9e-05 23.3 4.6 3.3 8.3 0.1 6.0 5 0 0 5 5 5 2 HEAT-like repeat TAN PF11640.8 OAJ31174.1 - 0.00014 22.0 0.4 1.8 8.7 0.0 5.2 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair Vac14_Fab1_bd PF12755.7 OAJ31174.1 - 0.00074 20.1 0.0 43 4.8 0.0 5.6 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 OAJ31174.1 - 0.0049 16.7 0.0 4.2 7.1 0.0 4.4 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 OAJ31174.1 - 0.015 15.6 1.2 2.1 8.7 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Proteasom_PSMB PF10508.9 OAJ31174.1 - 0.019 13.5 0.0 14 4.1 0.0 3.4 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 OAJ31174.1 - 0.034 14.3 0.1 4.6 7.4 0.0 4.1 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DCB PF16213.5 OAJ31174.1 - 0.056 13.1 1.3 1.5 8.4 0.0 3.9 4 1 1 5 5 5 0 Dimerisation and cyclophilin-binding domain of Mon2 Arm PF00514.23 OAJ31174.1 - 4.5 7.4 9.2 0.78 9.9 0.0 4.1 6 0 0 6 6 4 0 Armadillo/beta-catenin-like repeat LNS2 PF08235.13 OAJ31176.1 - 4.1e-97 324.1 0.0 1.2e-75 253.9 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 OAJ31176.1 - 2.1e-30 104.7 0.1 1.1e-19 70.3 0.0 2.5 2 0 0 2 2 2 2 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 OAJ31176.1 - 0.0098 15.5 0.0 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Bd3614-deam PF14439.6 OAJ31176.1 - 0.049 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase WRNPLPNID PF15017.6 OAJ31176.1 - 0.1 13.5 0.0 0.1 13.5 0.0 2.4 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box zf-H2C2 PF09337.10 OAJ31176.1 - 0.19 11.9 0.1 0.5 10.6 0.1 1.7 1 0 0 1 1 1 0 H2C2 zinc finger Transferase PF02458.15 OAJ31177.1 - 8.1e-08 31.3 0.0 3.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Transferase family EMC1_C PF07774.13 OAJ31178.1 - 5.7e-64 215.7 0.0 9.1e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 OAJ31178.1 - 1e-11 44.9 6.3 0.00016 21.4 0.1 3.9 3 0 0 3 3 3 3 PQQ-like domain PQQ PF01011.21 OAJ31178.1 - 3.6e-07 29.8 0.6 0.0013 18.5 0.1 4.0 3 0 0 3 3 3 2 PQQ enzyme repeat Cas_Cas5d PF09704.10 OAJ31178.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) adh_short_C2 PF13561.6 OAJ31179.1 - 9.1e-52 175.9 0.2 1.2e-51 175.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ31179.1 - 1.3e-47 161.8 0.3 1.7e-47 161.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ31179.1 - 1.3e-09 38.2 0.2 2.2e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ31179.1 - 0.018 14.5 0.2 0.041 13.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 OAJ31179.1 - 0.066 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.8 OAJ31179.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase B-block_TFIIIC PF04182.12 OAJ31180.1 - 2e-05 24.6 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 OAJ31180.1 - 0.014 15.9 0.0 3.8 8.1 0.0 3.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain PNGaseA PF12222.8 OAJ31181.1 - 2.9e-90 303.2 0.2 7.6e-90 301.8 0.2 1.6 1 1 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A SH3_9 PF14604.6 OAJ31183.1 - 4.4e-08 32.8 0.0 6.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ31183.1 - 9.3e-08 31.6 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ31183.1 - 0.00089 18.9 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 Variant SH3 domain NUDE_C PF04880.13 OAJ31183.1 - 7.2 7.1 7.1 0.85 10.1 2.5 1.7 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region NmrA PF05368.13 OAJ31185.1 - 6.4e-24 84.8 0.0 8.5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ31185.1 - 1.7e-14 54.1 0.0 4.1e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 OAJ31185.1 - 3.4e-06 27.3 0.0 6.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 OAJ31185.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 OAJ31185.1 - 0.027 14.7 0.1 0.1 12.8 0.0 2.0 3 0 0 3 3 3 0 TrkA-N domain NAD_binding_2 PF03446.15 OAJ31185.1 - 0.069 13.3 0.1 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase OPA3 PF07047.12 OAJ31186.1 - 3.3e-15 56.0 0.2 3.4e-15 55.9 0.2 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Pyr_redox_2 PF07992.14 OAJ31187.1 - 8.2e-68 228.8 8.2 8.2e-68 228.8 8.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ31187.1 - 9.6e-41 138.5 0.1 2.4e-40 137.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ31187.1 - 1.6e-20 73.4 12.6 1.7e-18 66.9 2.2 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ31187.1 - 5.6e-12 45.5 5.4 7.3e-09 35.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ31187.1 - 1.1e-11 44.8 0.4 1.1e-11 44.8 0.4 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ31187.1 - 1.7e-09 37.8 4.5 2.4e-05 24.5 0.4 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 OAJ31187.1 - 1.6e-07 30.8 15.1 2.7e-07 30.0 5.5 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 OAJ31187.1 - 1.7e-07 30.7 0.5 0.025 13.8 0.1 3.0 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 OAJ31187.1 - 2.7e-07 30.0 2.4 2.7e-07 30.0 2.4 3.6 3 1 0 4 4 4 1 FAD binding domain HI0933_like PF03486.14 OAJ31187.1 - 3.3e-06 26.1 14.1 0.00021 20.1 1.1 4.1 3 1 1 4 4 4 2 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ31187.1 - 9.5e-06 25.1 6.9 0.0016 17.8 1.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 OAJ31187.1 - 2.7e-05 23.5 5.3 6e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 OAJ31187.1 - 0.00036 19.9 12.3 0.0093 15.2 1.2 3.5 3 1 0 3 3 3 2 FAD binding domain THF_DHG_CYH_C PF02882.19 OAJ31187.1 - 0.031 13.6 0.1 0.13 11.6 0.1 2.0 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 OAJ31187.1 - 0.045 12.8 2.3 0.32 10.0 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 OAJ31187.1 - 0.065 12.8 22.7 0.42 10.1 2.3 4.1 2 2 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 OAJ31187.1 - 6.3 7.3 6.8 31 5.1 1.5 3.2 3 1 0 3 3 3 0 Putative NAD(P)-binding IGPS PF00218.21 OAJ31188.1 - 5e-83 278.2 0.0 2.4e-82 275.9 0.0 2.1 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 OAJ31188.1 - 4.9e-41 140.6 0.0 8.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 OAJ31188.1 - 7e-35 120.6 0.3 1.8e-28 99.6 0.1 3.1 2 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 OAJ31188.1 - 2.3e-06 27.5 0.3 6.8e-06 26.0 0.3 1.8 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 OAJ31188.1 - 0.039 13.7 1.7 0.06 13.1 0.2 2.1 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain ASF1_hist_chap PF04729.13 OAJ31190.1 - 4.7e-61 205.3 0.4 1.1e-60 204.0 0.4 1.5 1 1 0 1 1 1 1 ASF1 like histone chaperone Sad1_UNC PF07738.13 OAJ31191.1 - 1.3e-19 70.6 0.0 4.8e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF2849 PF11011.8 OAJ31191.1 - 5.4 7.8 9.8 2.4 8.9 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) Hydrolase_4 PF12146.8 OAJ31192.1 - 2.2e-15 56.6 0.0 6.3e-09 35.4 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ31192.1 - 3.9e-13 49.6 0.4 7.9e-08 32.3 0.3 2.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold AXE1 PF05448.12 OAJ31192.1 - 2.1e-06 26.7 0.0 0.0064 15.2 0.0 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 OAJ31192.1 - 0.0012 19.5 3.2 0.0012 19.5 3.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 OAJ31192.1 - 0.0027 17.6 0.0 0.033 14.1 0.0 2.5 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 OAJ31192.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 OAJ31192.1 - 0.029 13.9 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 OAJ31192.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ub-Mut7C PF14451.6 OAJ31192.1 - 0.077 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF1768 PF08719.11 OAJ31193.1 - 6.8e-24 84.9 0.0 8.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ31193.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.6 2 0 0 2 2 2 1 Bacteriophage protein GP30.3 zf-CSL PF05207.13 OAJ31194.1 - 4.5e-22 77.5 0.9 7.7e-22 76.8 0.9 1.4 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 OAJ31194.1 - 0.00067 19.7 0.5 0.0012 18.9 0.5 1.4 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 OAJ31194.1 - 0.0071 16.2 1.0 0.011 15.6 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_4 PF14570.6 OAJ31194.1 - 0.035 13.9 0.5 0.069 13.0 0.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_7 PF02591.15 OAJ31194.1 - 0.046 13.9 0.3 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 C4-type zinc ribbon domain U3_assoc_6 PF08640.11 OAJ31195.1 - 4.2e-13 49.2 0.2 1.4e-11 44.3 0.1 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Apc13p PF05839.11 OAJ31195.1 - 4.6 7.5 8.2 5.7 7.2 0.0 3.3 3 0 0 3 3 3 0 Apc13p protein Mob_synth_C PF06463.13 OAJ31198.1 - 4.1e-33 114.0 0.0 2.8e-32 111.3 0.0 2.0 1 1 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 OAJ31198.1 - 5.8e-29 101.6 0.0 8.6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 OAJ31198.1 - 7e-06 26.4 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 OAJ31198.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain MoaC PF01967.21 OAJ31199.1 - 4.9e-44 149.7 3.0 2.1e-22 79.7 0.0 2.2 2 0 0 2 2 2 2 MoaC family Glyoxalase_3 PF13468.6 OAJ31200.1 - 3.7e-23 82.5 4.6 1.1e-13 51.7 0.0 3.6 3 1 0 3 3 3 2 Glyoxalase-like domain CPSase_L_D2 PF02786.17 OAJ31201.1 - 1.5e-114 380.8 0.1 1.5e-82 276.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 OAJ31201.1 - 4.2e-48 162.4 0.0 8.6e-48 161.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 OAJ31201.1 - 9.2e-46 155.5 0.0 1.8e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 OAJ31201.1 - 1.7e-43 148.6 0.0 1e-42 146.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 OAJ31201.1 - 4e-39 133.7 0.0 8.5e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 OAJ31201.1 - 5.4e-30 104.5 0.0 1.1e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 OAJ31201.1 - 3.5e-18 65.9 0.1 2.2e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 OAJ31201.1 - 7.9e-16 58.1 0.1 1.9e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 OAJ31201.1 - 5e-11 42.6 0.0 1.7e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.6 OAJ31201.1 - 6e-11 42.2 0.1 1.6e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 OAJ31201.1 - 9.8e-05 22.5 0.1 0.58 10.2 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 OAJ31201.1 - 0.00011 22.0 0.1 0.0067 16.2 0.0 2.7 2 1 0 2 2 2 1 Peptidase C26 GARS_A PF01071.19 OAJ31201.1 - 0.004 17.0 0.0 0.16 11.7 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GMC_oxred_N PF00732.19 OAJ31202.1 - 3e-39 135.1 0.0 4.5e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ31202.1 - 9.6e-21 74.8 0.3 3.7e-20 72.9 0.1 2.1 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ31202.1 - 3.5e-09 36.2 1.7 2.2e-05 23.7 1.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ31202.1 - 3.4e-05 24.0 0.3 7.4e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ31202.1 - 0.00012 21.4 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ31202.1 - 0.00019 21.2 0.5 0.014 15.0 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ31202.1 - 0.0025 17.1 0.2 0.0063 15.8 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ31202.1 - 0.0089 15.4 1.4 0.013 14.9 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ31202.1 - 0.014 14.1 0.3 0.03 13.0 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein FliG_M PF14841.6 OAJ31202.1 - 0.033 14.4 0.2 0.073 13.3 0.0 1.6 2 0 0 2 2 1 0 FliG middle domain Thi4 PF01946.17 OAJ31202.1 - 0.044 13.0 0.3 0.092 12.0 0.3 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ31202.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ31202.1 - 0.092 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 OAJ31202.1 - 0.23 11.1 0.6 0.41 10.3 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_ligase_A_M PF01068.21 OAJ31204.1 - 6.7e-61 205.5 0.1 1.3e-60 204.5 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ31204.1 - 9e-46 156.4 0.1 1.7e-45 155.4 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 OAJ31204.1 - 4.9e-25 88.0 0.0 1.4e-24 86.5 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 OAJ31204.1 - 6.3e-05 23.3 0.0 0.00018 21.9 0.0 1.8 2 1 0 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 OAJ31204.1 - 0.013 15.5 0.2 4.2 7.5 0.0 2.8 2 0 0 2 2 2 0 DNA ligase OB-like domain Presenilin PF01080.17 OAJ31204.1 - 6.5 5.4 5.0 29 3.2 5.1 1.9 1 1 0 1 1 1 0 Presenilin SMC_N PF02463.19 OAJ31205.1 - 6.8e-70 234.9 0.0 5.6e-68 228.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ31205.1 - 7.5e-19 68.2 0.5 3.5e-18 66.0 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ31205.1 - 2.1e-14 54.5 16.4 2.1e-14 54.5 16.4 6.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 OAJ31205.1 - 6e-11 42.7 12.4 3.6e-05 23.7 0.3 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ31205.1 - 4.4e-05 23.1 0.0 0.00014 21.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.6 OAJ31205.1 - 0.0019 17.9 13.2 0.0019 17.9 13.2 7.4 5 3 3 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease FliJ PF02050.16 OAJ31205.1 - 0.0074 16.5 13.0 0.0074 16.5 13.0 9.1 5 3 5 10 10 10 1 Flagellar FliJ protein IGR PF09597.10 OAJ31205.1 - 0.12 12.5 0.6 0.81 9.8 0.4 2.5 1 1 1 2 2 2 0 IGR protein motif ABC_tran PF00005.27 OAJ31205.1 - 0.31 11.5 0.0 0.31 11.5 0.0 6.3 3 2 0 3 3 3 0 ABC transporter MCC-bdg_PDZ PF10506.9 OAJ31205.1 - 8.3 6.5 17.3 0.16 12.0 0.4 5.1 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Longin PF13774.6 OAJ31206.1 - 5.8e-21 74.3 0.0 9.7e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 OAJ31206.1 - 1.4e-13 50.4 0.2 3.3e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin AAA_2 PF07724.14 OAJ31207.1 - 5.1e-31 108.1 0.0 1.7e-23 83.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 OAJ31207.1 - 1.7e-12 47.9 0.0 3.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 OAJ31207.1 - 5.4e-11 42.4 0.0 1.3e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 OAJ31207.1 - 2.3e-05 23.6 0.0 7.3e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 OAJ31207.1 - 4.4e-05 23.8 0.2 0.00024 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 OAJ31207.1 - 0.0001 22.3 0.0 0.0003 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ31207.1 - 0.0032 17.9 0.0 0.013 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 OAJ31207.1 - 0.035 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 OAJ31207.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 OAJ31207.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ31207.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 OAJ31207.1 - 0.077 13.0 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 OAJ31207.1 - 0.078 13.5 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 OAJ31207.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 OAJ31207.1 - 0.1 12.0 1.4 0.67 9.3 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ31207.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 4HBT_2 PF13279.6 OAJ31208.1 - 1.3e-08 35.3 0.0 1.6e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 OAJ31208.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 OAJ31208.1 - 0.016 14.5 0.2 0.045 13.0 0.2 1.6 2 0 0 2 2 2 0 Acyl-ACP thioesterase Pec_lyase_C PF00544.19 OAJ31209.1 - 7e-14 51.9 4.9 1.2e-12 47.9 4.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 OAJ31209.1 - 1.5e-05 24.9 4.3 0.00013 21.8 3.1 2.3 1 1 1 2 2 2 2 Right handed beta helix region DAO PF01266.24 OAJ31210.1 - 4e-49 168.1 0.4 4e-49 168.1 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 OAJ31210.1 - 4e-45 152.7 0.2 8.7e-45 151.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 OAJ31210.1 - 8.9e-07 29.3 1.0 2e-06 28.1 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_2 PF00890.24 OAJ31210.1 - 5.7e-06 25.7 5.0 5.5e-05 22.4 5.0 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 OAJ31210.1 - 0.00047 19.6 0.9 0.00047 19.6 0.9 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase EF-hand_1 PF00036.32 OAJ31210.1 - 0.0007 19.0 0.6 0.0028 17.1 0.1 2.3 3 0 0 3 3 3 1 EF hand Pyr_redox_2 PF07992.14 OAJ31210.1 - 0.0047 16.2 0.7 0.013 14.8 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.6 OAJ31210.1 - 0.0077 15.7 0.5 0.018 14.6 0.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 OAJ31210.1 - 0.014 15.3 0.1 0.052 13.5 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain GIDA PF01134.22 OAJ31210.1 - 0.02 14.0 0.2 0.18 10.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ31210.1 - 0.085 12.1 0.1 1.6 7.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 OAJ31210.1 - 0.089 12.0 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 OAJ31210.1 - 0.1 12.4 0.2 0.27 11.1 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_8 PF13833.6 OAJ31210.1 - 0.44 10.4 3.3 1.1 9.2 0.1 3.0 3 1 1 4 4 4 0 EF-hand domain pair Topoisom_I_N PF02919.15 OAJ31211.1 - 5.4e-80 267.9 1.3 5.4e-80 267.9 1.3 3.9 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 OAJ31211.1 - 1.5e-68 230.5 0.1 1.5e-68 230.5 0.1 2.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 OAJ31211.1 - 2.2e-17 62.7 0.2 1.7e-14 53.4 0.1 3.0 2 0 0 2 2 2 2 C-terminal topoisomerase domain DUF5423 PF17461.2 OAJ31211.1 - 4.3 6.1 11.3 2.6 6.8 8.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5423) SNARE PF05739.19 OAJ31212.1 - 7e-16 58.0 0.1 1.3e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 OAJ31212.1 - 8.3e-07 28.9 2.0 0.0025 17.5 0.5 2.2 2 0 0 2 2 2 2 Syntaxin Syntaxin-5_N PF11416.8 OAJ31212.1 - 4.1e-05 22.7 0.7 4.1e-05 22.7 0.7 2.0 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain SlyX PF04102.12 OAJ31212.1 - 0.0071 16.9 0.3 0.079 13.6 0.3 2.7 2 0 0 2 2 2 1 SlyX DUF148 PF02520.17 OAJ31212.1 - 0.016 15.3 4.3 0.045 13.9 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF148 Use1 PF09753.9 OAJ31212.1 - 0.03 14.1 0.3 0.069 12.9 0.1 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 FlaC_arch PF05377.11 OAJ31212.1 - 0.039 14.4 1.0 0.12 12.8 0.9 1.9 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 OAJ31212.1 - 0.14 12.6 2.2 0.25 11.8 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 OAJ31212.1 - 0.26 11.3 7.0 2.3 8.3 0.3 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KxDL PF10241.9 OAJ31212.1 - 0.46 10.8 3.3 3.9 7.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein SKA2 PF16740.5 OAJ31212.1 - 2.7 7.8 4.5 14 5.5 0.3 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 NPV_P10 PF05531.12 OAJ31212.1 - 6.1 7.4 6.3 81 3.8 0.3 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Kelch_5 PF13854.6 OAJ31213.1 - 1.6e-32 110.9 9.8 1.8e-06 27.8 0.3 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 OAJ31213.1 - 1.2e-28 98.8 22.6 8.2e-07 28.9 0.2 7.8 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ31213.1 - 1.5e-28 98.5 20.6 2.6e-08 33.9 0.1 7.9 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 OAJ31213.1 - 1.1e-24 85.8 11.3 9.2e-07 28.9 0.1 7.1 5 1 2 7 7 7 5 Kelch motif Kelch_1 PF01344.25 OAJ31213.1 - 4.4e-22 77.4 19.1 3.2e-07 29.8 2.6 6.6 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 OAJ31213.1 - 2.3e-16 59.1 16.0 0.0021 18.0 0.2 7.1 6 1 0 6 6 6 5 Kelch motif MAD PF05557.13 OAJ31213.1 - 2.2 6.5 51.3 0.1 10.9 21.5 3.5 2 1 1 3 3 3 0 Mitotic checkpoint protein Vac7 PF12751.7 OAJ31215.1 - 8.7e-05 22.1 0.6 0.0001 21.9 0.6 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 TFIIA PF03153.13 OAJ31215.1 - 0.00026 21.1 2.6 0.00031 20.9 2.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FRQ PF09421.10 OAJ31215.1 - 0.0062 14.6 4.2 0.0074 14.4 4.2 1.1 1 0 0 1 1 1 1 Frequency clock protein Ndc1_Nup PF09531.10 OAJ31215.1 - 0.012 14.3 0.7 0.014 14.1 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPP4R2 PF09184.11 OAJ31215.1 - 0.15 11.6 4.6 0.19 11.3 4.6 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 OAJ31215.1 - 0.21 10.3 0.2 0.24 10.1 0.2 1.3 1 0 0 1 1 1 0 Presenilin CDC13_N PF16853.5 OAJ31215.1 - 0.26 10.8 2.8 0.39 10.2 2.8 1.2 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus TSP9 PF11493.8 OAJ31215.1 - 0.32 11.7 1.0 0.54 11.0 0.6 1.6 1 1 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 MRC1 PF09444.10 OAJ31215.1 - 0.58 10.7 11.5 0.94 10.0 11.5 1.3 1 0 0 1 1 1 0 MRC1-like domain SARAF PF06682.12 OAJ31215.1 - 1.6 8.3 8.6 2.9 7.5 8.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Conotoxin PF02950.17 OAJ31215.1 - 8.9 7.4 9.1 7.5 7.6 1.1 2.5 2 0 0 2 2 2 0 Conotoxin Flp_Fap PF04964.14 OAJ31216.1 - 0.018 14.9 2.7 0.034 14.0 1.8 1.9 1 1 1 2 2 2 0 Flp/Fap pilin component CclA_1 PF16942.5 OAJ31216.1 - 0.027 14.7 2.1 0.029 14.6 2.1 1.1 1 0 0 1 1 1 0 Putative cyclic bacteriocin IL32 PF15225.6 OAJ31216.1 - 1.7 9.0 3.5 21 5.6 0.5 2.0 1 1 1 2 2 2 0 Interleukin 32 SseC PF04888.12 OAJ31216.1 - 2.2 7.8 7.3 2.3 7.7 7.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF778 PF05608.12 OAJ31217.1 - 0.15 12.4 1.6 0.16 12.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Podoplanin PF05808.11 OAJ31217.1 - 1.8 8.7 3.9 2.6 8.2 3.9 1.4 1 1 0 1 1 1 0 Podoplanin MMS1_N PF10433.9 OAJ31218.1 - 2.6e-144 481.5 0.0 3.9e-144 480.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 OAJ31218.1 - 1.5e-79 267.7 0.0 3.9e-79 266.3 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region zf-B_box PF00643.24 OAJ31219.1 - 0.61 10.3 3.3 0.85 9.8 3.3 1.2 1 0 0 1 1 1 0 B-box zinc finger ADH_N PF08240.12 OAJ31220.1 - 2.1e-26 92.0 1.7 3.3e-26 91.3 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ31220.1 - 3.3e-10 40.0 0.0 7.3e-08 32.5 0.0 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 OAJ31220.1 - 0.0038 17.1 1.3 0.009 15.9 0.2 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 OAJ31220.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3136 PF11334.8 OAJ31220.1 - 0.18 11.6 0.0 0.68 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Senescence PF06911.12 OAJ31223.1 - 2.9e-32 112.5 1.4 4.5e-32 111.9 1.4 1.3 1 0 0 1 1 1 1 Senescence-associated protein DHquinase_II PF01220.19 OAJ31224.1 - 7e-60 200.7 0.0 9.1e-60 200.3 0.0 1.1 1 0 0 1 1 1 1 Dehydroquinase class II GP40 PF11025.8 OAJ31224.1 - 0.1 12.3 0.0 0.6 9.9 0.0 1.9 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium LRR_4 PF12799.7 OAJ31225.1 - 1.2e-30 105.1 22.8 8.5e-07 29.2 0.4 6.8 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 OAJ31225.1 - 1.1e-29 101.9 48.6 2.7e-08 33.4 4.4 6.2 2 1 6 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 OAJ31225.1 - 1.3e-18 67.2 3.8 2.4e-09 36.9 0.3 4.0 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 OAJ31225.1 - 1.2e-07 31.2 18.2 0.41 10.8 0.1 8.8 10 0 0 10 10 10 2 Leucine Rich repeat LRR_1 PF00560.33 OAJ31225.1 - 1.8e-06 27.7 21.2 4.8 8.1 0.4 9.7 10 1 0 10 10 10 1 Leucine Rich Repeat Arm_3 PF16186.5 OAJ31225.1 - 0.19 11.3 0.7 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Atypical Arm repeat Arylsulfotran_2 PF14269.6 OAJ31226.1 - 2.1e-36 125.8 0.0 5.9e-36 124.4 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 OAJ31226.1 - 6.1e-09 35.2 2.6 1.4e-08 34.0 2.7 1.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Sulfotransfer_4 PF17784.1 OAJ31227.1 - 5.9e-46 157.0 0.0 9.1e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain GMC_oxred_N PF00732.19 OAJ31227.1 - 1.4e-39 136.2 1.4 1.1e-37 130.0 0.3 2.8 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ31227.1 - 1.6e-28 100.0 1.3 1.9e-28 99.8 0.1 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Sulfotransfer_3 PF13469.6 OAJ31227.1 - 0.00072 20.0 0.2 0.0065 16.9 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase family CBM_5_12 PF02839.14 OAJ31227.1 - 0.07 13.7 2.1 0.26 11.9 0.3 2.8 2 0 0 2 2 2 0 Carbohydrate binding domain Enolase_like_N PF18374.1 OAJ31227.1 - 0.51 9.8 2.3 1.7 8.1 0.1 2.6 3 0 0 3 3 3 0 Enolase N-terminal domain-like FHA PF00498.26 OAJ31228.1 - 7.3e-15 55.1 0.0 1.2e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 OAJ31228.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Esterase PF00756.20 OAJ31229.1 - 0.00023 20.9 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Asp2 PF16929.5 OAJ31229.1 - 0.037 13.0 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Ribosomal_S9 PF00380.19 OAJ31229.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Pox_MCEL PF03291.16 OAJ31230.1 - 1.2e-73 248.1 0.0 1.7e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 OAJ31230.1 - 5.4e-12 46.3 0.0 1.3e-11 45.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31230.1 - 2.6e-10 40.3 0.0 3.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ31230.1 - 2.1e-08 34.2 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ31230.1 - 9.9e-08 32.5 0.0 2.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ31230.1 - 1.3e-06 29.1 0.0 3.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 OAJ31230.1 - 0.00037 19.8 0.0 0.002 17.3 0.0 1.9 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 OAJ31230.1 - 0.004 16.7 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 OAJ31230.1 - 0.026 13.9 0.1 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PTS_EIIC_2 PF13303.6 OAJ31230.1 - 0.62 9.0 3.6 1 8.3 3.6 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FAD_binding_3 PF01494.19 OAJ31231.1 - 4.1e-17 62.5 0.0 6.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ31231.1 - 5.7e-06 25.8 0.0 0.01 15.1 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ31231.1 - 0.0049 17.1 0.1 0.0099 16.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 OAJ31231.1 - 0.012 14.7 0.0 0.043 12.9 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.16 OAJ31231.1 - 0.021 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 OAJ31231.1 - 0.076 12.3 0.2 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ31231.1 - 0.1 12.1 0.1 3.1 7.3 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ31231.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding TMEM141 PF15110.6 OAJ31234.1 - 1.4 9.5 3.3 13 6.5 0.1 2.7 2 1 0 2 2 2 0 TMEM141 protein family PepSY_TM PF03929.16 OAJ31234.1 - 9.6 5.8 11.6 2 8.0 5.3 2.6 3 0 0 3 3 3 0 PepSY-associated TM region Pkinase PF00069.25 OAJ31235.1 - 0.0002 20.8 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31235.1 - 0.00084 18.7 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4714 PF15833.5 OAJ31236.1 - 0.14 12.1 0.5 0.28 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) LapA_dom PF06305.11 OAJ31236.1 - 1.1 9.2 3.6 0.42 10.5 0.8 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PDEase_I_N PF08499.12 OAJ31237.1 - 0.093 12.6 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Asn_synthase PF00733.21 OAJ31238.1 - 2.5e-89 300.4 0.1 3.9e-55 188.0 0.0 2.7 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 OAJ31238.1 - 3.9e-37 126.9 0.0 6e-37 126.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 OAJ31238.1 - 1e-28 100.2 0.0 2.8e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 OAJ31238.1 - 3.6e-05 23.3 0.0 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 Aluminium induced protein NAD_synthase PF02540.17 OAJ31238.1 - 0.084 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Jun PF03957.13 OAJ31238.1 - 0.087 12.7 0.1 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Jun-like transcription factor QueC PF06508.13 OAJ31238.1 - 0.17 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC PQ-loop PF04193.14 OAJ31239.1 - 2.2e-35 120.2 6.3 1.4e-17 63.2 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 OAJ31239.1 - 0.016 15.2 0.4 0.016 15.2 0.4 2.1 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange GyrB_insert PF18053.1 OAJ31239.1 - 0.064 13.1 0.7 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit insert domain Tannase PF07519.11 OAJ31241.1 - 7.8e-45 153.6 0.1 3.8e-36 125.0 0.1 2.4 1 1 1 2 2 2 2 Tannase and feruloyl esterase WD40 PF00400.32 OAJ31241.1 - 2.8e-37 126.1 13.7 2.2e-07 31.5 0.4 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 OAJ31241.1 - 0.025 13.3 0.2 6.5 5.3 0.0 3.0 1 1 1 3 3 3 0 Nucleoporin Nup120/160 nos_propeller_2 PF18793.1 OAJ31241.1 - 0.13 12.6 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat 2 DUF1264 PF06884.11 OAJ31242.1 - 2e-48 164.2 0.0 3.5e-48 163.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1264) UDPG_MGDP_dh_N PF03721.14 OAJ31243.1 - 7e-62 208.3 0.0 1.3e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 OAJ31243.1 - 3.4e-34 117.4 0.1 6.6e-33 113.3 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 OAJ31243.1 - 1.2e-32 111.9 0.0 2.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 OAJ31243.1 - 0.0081 16.7 0.1 6.7 7.4 0.1 2.9 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 OAJ31243.1 - 0.053 13.5 0.1 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 OAJ31243.1 - 0.099 12.9 0.0 0.28 11.5 0.0 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 OAJ31243.1 - 0.14 12.4 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase SET PF00856.28 OAJ31245.1 - 3.5e-06 27.5 0.0 2.5e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 SET domain Thioredoxin_7 PF13899.6 OAJ31246.1 - 6.9e-05 22.9 0.1 0.00024 21.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like UBX PF00789.20 OAJ31246.1 - 7.3e-05 22.9 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain Radial_spoke_3 PF06098.11 OAJ31246.1 - 2 7.7 10.7 5.6 6.2 10.4 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 U79_P34 PF03064.16 OAJ31246.1 - 4 6.7 6.9 6.9 5.9 6.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SIS PF01380.22 OAJ31247.1 - 4.9e-14 52.3 0.0 5.1e-13 49.0 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 OAJ31247.1 - 0.0011 19.0 0.0 0.024 14.6 0.0 2.3 1 1 1 2 2 2 1 SIS domain Glyco_hydro_38N PF01074.22 OAJ31248.1 - 5.6e-74 249.1 0.7 9.1e-74 248.4 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 OAJ31248.1 - 1.2e-47 162.7 0.0 2.4e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 OAJ31248.1 - 1e-25 89.7 0.0 2.7e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 OAJ31248.1 - 1.5e-08 34.6 0.0 3.6e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 OAJ31248.1 - 0.0023 17.2 0.0 0.0046 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Defensin_2 PF01097.18 OAJ31251.1 - 0.042 13.8 1.4 0.11 12.4 1.4 1.7 1 0 0 1 1 1 0 Arthropod defensin NDUFA12 PF05071.16 OAJ31252.1 - 1.9e-09 38.2 0.2 3.6e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hid1 PF12722.7 OAJ31252.1 - 1.1 7.3 3.3 1.2 7.2 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein F-box PF00646.33 OAJ31253.1 - 1.2e-07 31.4 2.3 1.4e-06 28.0 0.2 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 OAJ31253.1 - 3.6e-05 23.6 2.5 3.6e-05 23.6 2.5 2.2 2 0 0 2 2 2 1 F-box-like CSTF2_hinge PF14327.6 OAJ31253.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 MFS_1 PF07690.16 OAJ31254.1 - 2.5e-30 105.6 23.1 2.5e-30 105.6 23.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 OAJ31254.1 - 5.4e-05 21.8 0.3 0.00012 20.7 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 OAJ31254.1 - 0.0039 15.5 2.0 0.0083 14.5 2.0 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family EMP70 PF02990.16 OAJ31254.1 - 0.17 10.5 6.6 0.33 9.6 6.6 1.4 1 0 0 1 1 1 0 Endomembrane protein 70 Pea-VEAacid PF08111.11 OAJ31255.1 - 0.15 12.4 0.4 0.33 11.4 0.4 1.5 1 0 0 1 1 1 0 Pea-VEAacid family MFS_1 PF07690.16 OAJ31256.1 - 0.00025 20.1 3.8 0.00037 19.5 3.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1768 PF08719.11 OAJ31257.1 - 0.19 12.0 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) NUDIX PF00293.28 OAJ31259.1 - 5.6e-08 32.9 0.1 1.3e-07 31.7 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain GATase_4 PF13230.6 OAJ31259.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Lon_C PF05362.13 OAJ31260.1 - 2.7e-66 223.0 0.2 5.6e-66 222.0 0.2 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 OAJ31260.1 - 1.9e-31 109.5 0.0 4.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 OAJ31260.1 - 1.9e-21 76.8 0.0 7.2e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 OAJ31260.1 - 1.5e-06 28.0 0.0 3.9e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 OAJ31260.1 - 4.6e-06 26.9 0.0 8.5e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 OAJ31260.1 - 6.5e-06 26.2 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 OAJ31260.1 - 7.4e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 OAJ31260.1 - 0.0011 18.7 0.0 0.0039 17.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ31260.1 - 0.0012 19.2 0.0 0.0045 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ31260.1 - 0.0017 18.6 0.4 0.069 13.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 OAJ31260.1 - 0.0041 17.7 0.9 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ31260.1 - 0.023 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 OAJ31260.1 - 0.041 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 OAJ31260.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 OAJ31260.1 - 0.086 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 OAJ31260.1 - 0.093 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 OAJ31260.1 - 0.1 11.8 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 OAJ31260.1 - 0.12 12.2 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 OAJ31260.1 - 0.15 12.6 1.5 0.37 11.3 0.1 2.3 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 OAJ31260.1 - 0.24 11.3 2.9 17 5.2 0.0 3.3 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea DUF35_N PF12172.8 OAJ31261.1 - 0.0076 16.1 1.6 33 4.5 0.0 4.7 5 0 0 5 5 5 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Muted PF14942.6 OAJ31261.1 - 0.015 15.7 3.6 5 7.4 0.1 3.6 1 1 3 4 4 4 0 Organelle biogenesis, Muted-like protein DrsE_2 PF13686.6 OAJ31261.1 - 0.094 12.6 1.3 21 5.0 0.0 4.0 6 0 0 6 6 6 0 DsrE/DsrF/DrsH-like family DUF4423 PF14394.6 OAJ31261.1 - 0.13 12.0 1.0 76 3.0 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4423) Phage_CI_C PF16452.5 OAJ31261.1 - 0.28 11.5 14.1 5.7 7.3 0.2 5.6 5 2 1 7 7 7 0 Bacteriophage CI repressor C-terminal domain DUF2540 PF10802.8 OAJ31261.1 - 0.28 11.3 2.4 6.1 7.0 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2540) DUF4588 PF15251.6 OAJ31261.1 - 0.54 10.0 6.6 2.6 7.7 0.3 3.8 1 1 2 4 4 4 0 Domain of unknown function (DUF4588) Endonuc-PvuII PF09225.10 OAJ31261.1 - 0.98 9.2 11.4 1.6 8.5 0.1 4.4 3 2 2 6 6 6 0 Restriction endonuclease PvuII Late_protein_L2 PF00513.18 OAJ31261.1 - 3.4 6.6 7.3 2.7 6.9 0.5 3.0 1 1 1 3 3 3 0 Late Protein L2 CRAL_TRIO PF00650.20 OAJ31262.1 - 5.2e-27 94.5 0.0 9.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ31262.1 - 1.9e-10 40.7 0.5 6.4e-10 39.1 0.3 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 OAJ31262.1 - 8.2e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Brr6_like_C_C PF10104.9 OAJ31263.1 - 1e-36 125.7 0.3 1.4e-36 125.2 0.3 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF1768 PF08719.11 OAJ31264.1 - 3.7e-24 85.8 0.0 8.2e-24 84.7 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 OAJ31265.1 - 7.4e-10 39.3 3.6 6.1e-06 26.6 0.0 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF1768) PSD1 PF07587.11 OAJ31267.1 - 0.11 11.9 0.4 0.2 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Corona_M PF01635.18 OAJ31267.1 - 0.18 11.1 4.0 0.34 10.2 4.0 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Translin PF01997.16 OAJ31269.1 - 4.9e-44 150.8 0.1 6e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Translin family BLOC1_2 PF10046.9 OAJ31269.1 - 0.027 14.8 0.1 0.58 10.5 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mad3_BUB1_I PF08311.12 OAJ31270.1 - 2.4e-36 124.5 0.2 3.8e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 OAJ31270.1 - 1.9e-06 27.4 0.0 3.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31270.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4484 PF14831.6 OAJ31270.1 - 2.1 8.4 6.3 0.27 11.2 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Cellulase PF00150.18 OAJ31271.1 - 1.1e-17 64.4 4.8 3.7e-17 62.7 4.8 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1554 PF07588.11 OAJ31271.1 - 1.4 8.7 5.8 0.18 11.6 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1554) CDP-OH_P_transf PF01066.21 OAJ31272.1 - 2.9e-13 50.4 0.4 8.5e-13 48.9 0.4 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase EST1_DNA_bind PF10373.9 OAJ31273.1 - 4.5e-31 108.4 0.0 7.9e-24 84.6 0.0 3.2 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 OAJ31273.1 - 9.4e-17 61.9 0.0 4e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 Secretin_N_2 PF07655.13 OAJ31273.1 - 0.027 15.0 0.2 0.027 15.0 0.2 3.7 4 0 0 4 4 4 0 Secretin N-terminal domain NAD_binding_11 PF14833.6 OAJ31274.1 - 2.9e-29 101.8 0.1 5.8e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 OAJ31274.1 - 3.9e-29 101.9 0.0 8.1e-29 100.8 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ntox10 PF15520.6 OAJ31274.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Novel toxin 10 Tubulin_2 PF13809.6 OAJ31274.1 - 0.089 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin like LcrG PF07216.12 OAJ31274.1 - 0.17 11.8 0.0 3.7 7.5 0.0 2.8 3 0 0 3 3 3 0 LcrG protein 2OG-FeII_Oxy_3 PF13640.6 OAJ31275.1 - 1.6e-07 32.1 0.1 3.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1885 PF08968.10 OAJ31275.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) VID27_N PF17748.1 OAJ31276.1 - 7.6e-08 32.4 1.0 1.1e-07 31.8 0.8 1.3 1 1 0 1 1 1 1 VID27 N-terminal region Ras PF00071.22 OAJ31277.1 - 6.6e-54 181.9 0.0 7.5e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ31277.1 - 3e-21 75.8 0.0 4e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ31277.1 - 6.9e-06 25.6 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ31277.1 - 0.0031 17.1 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ribo_biogen_C PF04034.13 OAJ31278.1 - 6e-47 158.5 0.0 8.8e-47 158.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 OAJ31278.1 - 6.8e-14 51.4 0.1 1.3e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.12 OAJ31278.1 - 4.2 6.7 22.8 1.2 8.4 15.5 2.1 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.13 OAJ31278.1 - 6.5 6.6 21.6 23 4.8 17.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.11 OAJ31278.1 - 8.9 5.9 13.1 9.6 5.8 8.2 2.1 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) ICL PF00463.21 OAJ31279.1 - 3.5e-264 877.2 1.5 4e-264 877.0 1.5 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 OAJ31279.1 - 2.6e-09 36.9 0.0 4.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 OAJ31279.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Rhomboid_N PF12122.8 OAJ31279.1 - 0.12 12.6 0.0 20 5.4 0.0 2.9 2 0 0 2 2 2 0 Cytoplasmic N-terminal domain of rhomboid serine protease Clr2_transil PF16761.5 OAJ31280.1 - 9.2e-08 32.8 1.3 1.7e-07 32.0 1.3 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 OAJ31280.1 - 0.00023 22.0 0.0 0.00046 21.0 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 PI-PLC-C1 PF16670.5 OAJ31281.1 - 0.021 13.9 0.1 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent LapA_dom PF06305.11 OAJ31282.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HemY_N PF07219.13 OAJ31282.1 - 0.58 10.4 1.6 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Kinesin PF00225.23 OAJ31283.1 - 1.8e-105 352.6 0.1 4.4e-105 351.3 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ31283.1 - 2e-26 92.7 0.0 5.1e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Type2_restr_D3 PF16902.5 OAJ31283.1 - 0.066 13.1 0.0 0.48 10.4 0.0 2.5 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain PI-PLC-C1 PF16670.5 OAJ31284.1 - 0.0026 16.9 0.4 1.4 7.9 0.0 2.4 1 1 1 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent SUI1 PF01253.22 OAJ31285.1 - 2.3e-12 47.3 0.1 4.4e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 YscO PF07321.12 OAJ31285.1 - 0.012 15.6 2.8 0.021 14.8 2.8 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO GA PF01468.17 OAJ31285.1 - 0.78 10.1 7.6 0.18 12.1 1.9 2.7 3 0 0 3 3 3 0 GA module BRO1 PF03097.18 OAJ31286.1 - 6.1e-103 344.6 0.0 1.5e-102 343.3 0.0 1.7 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 OAJ31286.1 - 7e-68 229.1 13.3 7e-68 229.1 13.3 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV CAP_N PF01213.19 OAJ31286.1 - 0.0068 15.9 2.7 0.016 14.8 2.7 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF3294 PF07957.11 OAJ31286.1 - 0.032 14.0 2.1 0.073 12.8 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) ABC_tran_CTD PF16326.5 OAJ31286.1 - 1.1 9.6 8.0 0.23 11.7 0.3 3.3 2 2 1 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 OAJ31286.1 - 7.1 5.9 10.5 6.1 6.1 4.3 2.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GST_N PF02798.20 OAJ31287.1 - 2e-09 37.6 0.0 4.1e-09 36.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ31287.1 - 1e-08 35.5 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 OAJ31287.1 - 2.6e-05 24.4 0.0 8.4e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 OAJ31287.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 OAJ31287.1 - 0.0012 18.8 0.0 0.0035 17.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ31287.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_3 PF00202.21 OAJ31288.1 - 3.9e-35 121.3 0.0 1.2e-16 60.4 0.0 3.4 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 OAJ31288.1 - 7.9e-12 45.4 0.0 4.2e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Gcd10p PF04189.13 OAJ31289.1 - 5.3e-64 216.2 0.0 9.4e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family Ribosomal_S10 PF00338.22 OAJ31290.1 - 1.8e-27 95.4 0.2 2.2e-27 95.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2076 PF09849.9 OAJ31291.1 - 0.0056 16.8 0.4 0.0094 16.0 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) PMT PF02366.18 OAJ31293.1 - 8.9e-78 261.2 16.2 1.6e-77 260.4 16.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ31293.1 - 1.6e-60 204.1 4.2 2.8e-60 203.4 0.4 2.6 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ31293.1 - 4.4e-12 46.2 0.4 1.1e-11 45.0 0.2 1.7 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 OAJ31293.1 - 2e-05 24.9 10.2 2e-05 24.9 10.2 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 OAJ31294.1 - 4.3e-40 135.0 15.1 5.4e-08 33.4 0.1 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ31294.1 - 3.6e-15 56.0 0.4 9.6e-05 22.6 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 OAJ31294.1 - 1.2e-13 50.3 3.5 2.3e-13 49.5 3.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 OAJ31294.1 - 2.7e-06 26.9 0.0 0.00058 19.3 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain Nbas_N PF15492.6 OAJ31294.1 - 0.00014 21.3 0.1 0.0072 15.7 0.0 2.9 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 OAJ31294.1 - 0.00026 20.1 0.0 1.7 7.5 0.0 3.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ31294.1 - 0.088 11.4 0.0 2.6 6.6 0.0 2.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ribosomal_L24e PF01246.20 OAJ31295.1 - 1.2e-32 111.9 5.1 2.8e-32 110.7 5.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Flu_M1 PF00598.19 OAJ31295.1 - 0.062 12.8 0.2 0.091 12.3 0.2 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) R2K_3 PF14243.6 OAJ31295.1 - 0.073 13.1 0.7 0.092 12.7 0.7 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Terminase_3C PF17288.2 OAJ31295.1 - 0.096 13.1 0.3 0.14 12.5 0.3 1.3 1 1 0 1 1 1 0 Terminase RNAseH like domain HAGH_C PF16123.5 OAJ31295.1 - 0.15 12.6 2.6 0.14 12.7 0.7 1.9 1 1 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus DUF2116 PF09889.9 OAJ31295.1 - 1.1 9.3 5.4 5 7.2 0.7 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Glyco_hydro_cc PF11790.8 OAJ31296.1 - 1.9e-49 168.4 0.7 2.5e-49 168.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core TFIIA PF03153.13 OAJ31296.1 - 1.2 9.0 8.1 1.7 8.6 8.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 OAJ31296.1 - 7.8 5.8 7.6 11 5.3 7.6 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ31297.1 - 0.54 8.4 31.1 0.16 10.2 16.0 2.1 2 0 0 2 2 2 0 Nop14-like family Tropomyosin PF00261.20 OAJ31298.1 - 0.0045 16.4 22.0 0.0045 16.4 22.0 8.5 2 1 5 7 7 7 4 Tropomyosin Filament PF00038.21 OAJ31298.1 - 1.4 8.4 183.4 0.06 12.9 17.7 8.3 1 1 3 6 6 6 0 Intermediate filament protein RTBV_P46 PF06216.11 OAJ31298.1 - 1.7 7.4 6.3 0.92 8.3 0.6 2.4 1 1 0 2 2 2 0 Rice tungro bacilliform virus P46 protein Nucleopor_Nup85 PF07575.13 OAJ31299.1 - 9.4e-74 249.0 0.0 4.5e-39 134.5 0.0 2.7 2 1 0 2 2 2 2 Nup85 Nucleoporin DUF1640 PF07798.11 OAJ31302.1 - 2.6e-60 203.4 3.2 3.2e-60 203.1 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 OAJ31302.1 - 0.13 12.5 2.9 0.57 10.4 2.9 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper ParBc_2 PF08857.11 OAJ31302.1 - 0.14 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative ParB-like nuclease DUF5082 PF16888.5 OAJ31302.1 - 1.6 9.0 5.3 6.4 7.1 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) NUDIX PF00293.28 OAJ31303.1 - 0.0011 19.0 1.6 1.5 8.9 0.1 2.9 2 1 1 3 3 3 2 NUDIX domain Zds_C PF08632.10 OAJ31304.1 - 1.2e-26 92.2 1.1 2.1e-26 91.4 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CLN3 PF02487.17 OAJ31304.1 - 1.4 7.9 4.8 4 6.4 4.8 1.7 1 0 0 1 1 1 0 CLN3 protein Serinc PF03348.15 OAJ31304.1 - 4.2 6.2 3.7 9.4 5.0 3.7 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Guanylate_kin PF00625.21 OAJ31305.1 - 3.4e-54 183.3 0.0 4.1e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 OAJ31305.1 - 5.1e-07 30.2 0.4 1.2e-06 29.0 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 OAJ31305.1 - 5.3e-07 30.0 0.0 1.2e-06 28.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 OAJ31305.1 - 3.7e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 OAJ31305.1 - 0.00034 21.2 0.0 0.00055 20.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 OAJ31305.1 - 0.00038 20.6 0.1 0.00067 19.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ31305.1 - 0.00039 21.0 0.1 0.0011 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ31305.1 - 0.00079 19.2 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAJ31305.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 OAJ31305.1 - 0.0018 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 OAJ31305.1 - 0.0023 18.0 0.0 0.0053 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 OAJ31305.1 - 0.0049 16.6 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 OAJ31305.1 - 0.0063 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 OAJ31305.1 - 0.0072 16.3 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 OAJ31305.1 - 0.0076 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 OAJ31305.1 - 0.012 15.7 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAJ31305.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 OAJ31305.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 OAJ31305.1 - 0.026 14.8 1.2 0.06 13.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 OAJ31305.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PTE PF02126.18 OAJ31305.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotriesterase family Septin PF00735.18 OAJ31305.1 - 0.05 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Septin DUF815 PF05673.13 OAJ31305.1 - 0.051 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 OAJ31305.1 - 0.057 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 OAJ31305.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ31305.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 OAJ31305.1 - 0.07 13.6 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 OAJ31305.1 - 0.071 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PTS_IIB PF02302.17 OAJ31305.1 - 0.08 13.6 0.0 0.56 10.9 0.0 2.3 3 0 0 3 3 2 0 PTS system, Lactose/Cellobiose specific IIB subunit AAA_19 PF13245.6 OAJ31305.1 - 0.086 13.2 0.0 0.5 10.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 OAJ31305.1 - 0.11 11.7 0.0 0.28 10.4 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AFG1_ATPase PF03969.16 OAJ31305.1 - 0.11 11.4 0.0 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase cobW PF02492.19 OAJ31305.1 - 0.2 11.3 0.0 0.43 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PNP_UDP_1 PF01048.20 OAJ31306.1 - 1.3e-30 106.5 4.6 1.3e-29 103.1 4.6 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily AF-4 PF05110.13 OAJ31307.1 - 2 6.4 8.0 3.1 5.8 8.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Na_H_Exchanger PF00999.21 OAJ31308.1 - 4.6e-56 190.2 10.9 6.2e-56 189.8 10.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 OAJ31308.1 - 0.003 17.6 2.4 0.021 14.9 0.0 3.0 3 0 0 3 3 3 1 YrhC-like protein 7tm_3 PF00003.22 OAJ31308.1 - 2.2 7.9 9.8 0.077 12.7 2.1 2.2 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DHquinase_I PF01487.15 OAJ31309.1 - 1.1e-36 127.3 0.0 5e-36 125.1 0.0 2.0 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 OAJ31309.1 - 4e-20 72.5 0.0 6.9e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 OAJ31309.1 - 0.03 14.9 0.0 0.072 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain QueF_N PF14819.6 OAJ31311.1 - 5.6e-06 26.6 0.5 0.72 10.2 0.1 3.4 3 0 0 3 3 3 3 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term LepB_GAP_C PF18227.1 OAJ31311.1 - 0.0049 17.3 0.0 2.1 9.0 0.0 3.1 1 1 3 4 4 4 2 LepB GAP domain C-terminal subdomain CAP_GLY PF01302.25 OAJ31311.1 - 0.059 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain AIRC PF00731.20 OAJ31312.1 - 1.4e-55 187.0 1.9 2.2e-55 186.3 0.9 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 OAJ31312.1 - 5.9e-52 175.7 0.0 1.9e-29 102.5 0.0 2.3 1 1 1 2 2 2 2 ATP-grasp domain PurK_C PF17769.1 OAJ31312.1 - 1.4e-17 63.1 0.0 3e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 OAJ31312.1 - 5.9e-05 22.7 0.0 0.00018 21.1 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 OAJ31312.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 OAJ31312.1 - 0.0024 17.4 0.0 0.0081 15.7 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.18 OAJ31312.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PrpR_N PF06506.11 OAJ31312.1 - 0.055 13.0 0.0 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator HTH_9 PF08221.11 OAJ31313.1 - 6.2e-19 67.9 0.3 6.2e-07 29.4 0.0 4.5 4 0 0 4 4 4 4 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 OAJ31313.1 - 2.6e-10 40.5 0.0 5.3e-08 32.9 0.0 3.1 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 OAJ31313.1 - 6.8e-07 29.1 0.0 0.00031 20.6 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit SNF2_N PF00176.23 OAJ31314.1 - 3.9e-35 121.2 0.0 1.4e-28 99.7 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ31314.1 - 6.6e-06 26.4 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CRF PF00473.17 OAJ31314.1 - 0.65 10.1 3.1 21 5.3 0.4 3.7 3 0 0 3 3 3 0 Corticotropin-releasing factor family FUSC_2 PF13515.6 OAJ31315.1 - 5.9e-22 78.1 10.2 5.9e-22 78.1 10.2 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAJ31315.1 - 4.6e-13 48.8 2.2 1.1e-09 37.7 0.4 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 OAJ31315.1 - 1.2e-10 40.6 10.3 2e-10 39.9 1.5 3.0 3 1 0 3 3 3 2 Fusaric acid resistance protein family ArAE_2 PF10334.9 OAJ31315.1 - 7.9e-09 35.7 0.3 2.2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 OAJ31315.1 - 0.0036 16.4 1.1 0.43 9.6 0.5 2.4 2 0 0 2 2 2 2 FUSC-like inner membrane protein yccS EF-1_beta_acid PF10587.9 OAJ31315.1 - 8.1 7.0 7.3 26 5.4 7.3 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region PMT PF02366.18 OAJ31316.1 - 1.5e-72 244.1 17.3 2.3e-72 243.5 17.3 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 OAJ31316.1 - 4.9e-51 173.2 8.5 1.6e-50 171.5 8.5 1.9 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 OAJ31316.1 - 5.1e-26 91.7 0.1 8.9e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 MIR domain AbiEi_4 PF13338.6 OAJ31318.1 - 0.0092 16.1 1.1 0.021 15.0 1.1 1.7 1 1 0 1 1 1 1 Transcriptional regulator, AbiEi antitoxin DUF4218 PF13960.6 OAJ31319.1 - 0.0014 18.3 0.1 0.0025 17.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TPR_MalT PF17874.1 OAJ31320.1 - 0.0085 15.5 0.1 0.0085 15.5 0.1 3.5 2 1 1 3 3 3 1 MalT-like TPR region TPR_2 PF07719.17 OAJ31320.1 - 0.048 13.8 6.1 2.2 8.6 0.8 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ31320.1 - 0.056 13.5 1.1 13 6.1 0.4 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ31320.1 - 0.092 12.6 2.2 14 5.7 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIA PF03153.13 OAJ31320.1 - 9.7 6.1 14.8 17 5.3 14.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DIOX_N PF14226.6 OAJ31321.1 - 2.3e-16 60.6 0.0 4.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 OAJ31321.1 - 5.1e-16 59.0 0.0 9.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.13 OAJ31322.1 - 5.4e-14 52.3 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 OAJ31322.1 - 4.4e-07 30.0 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 OAJ31322.1 - 0.082 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DeoC PF01791.9 OAJ31324.1 - 1.6e-11 44.3 1.1 3.4e-11 43.2 1.1 1.5 1 1 0 1 1 1 1 DeoC/LacD family aldolase RebB PF11747.8 OAJ31324.1 - 0.068 13.3 8.1 0.22 11.6 8.1 1.8 1 0 0 1 1 1 0 Killing trait UPF0121 PF03661.13 OAJ31325.1 - 1.2e-37 129.6 7.9 1.6e-37 129.2 7.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2101 PF09874.9 OAJ31325.1 - 0.073 12.8 0.1 0.073 12.8 0.1 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) SNF2_N PF00176.23 OAJ31326.1 - 3.9e-64 216.6 0.1 7e-64 215.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ31326.1 - 6.5e-19 68.3 0.0 4.1e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ31326.1 - 9.9e-11 41.9 0.1 4.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 OAJ31326.1 - 0.054 13.8 16.6 0.39 11.1 16.6 2.5 1 1 0 1 1 1 0 HSA HDA2-3 PF11496.8 OAJ31326.1 - 0.09 11.9 0.2 9.4 5.3 0.0 2.5 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Tex_N PF09371.10 OAJ31326.1 - 0.094 12.4 3.8 0.67 9.6 3.7 2.2 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Helicase_C PF00271.31 OAJ31327.1 - 7.8e-11 42.3 0.0 1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fer2 PF00111.27 OAJ31329.1 - 9e-09 35.2 2.0 6.2e-08 32.5 2.0 2.1 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SNase PF00565.17 OAJ31330.1 - 5.8e-45 152.2 0.9 2.9e-17 63.1 0.0 7.2 7 0 0 7 7 7 5 Staphylococcal nuclease homologue TUDOR PF00567.24 OAJ31330.1 - 9.1e-20 70.9 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 OAJ31330.1 - 1.6e-05 25.2 0.0 0.00017 22.0 0.0 2.6 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 OAJ31330.1 - 0.0046 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) WD40 PF00400.32 OAJ31331.1 - 5.1e-36 122.1 19.4 1.2e-08 35.5 0.5 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ31331.1 - 6.5e-14 52.0 0.0 0.0021 18.3 0.0 4.6 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ31331.1 - 0.011 14.8 0.2 5.4 5.9 0.1 3.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 OAJ31331.1 - 0.022 14.5 0.1 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Abhydrolase_1 PF00561.20 OAJ31332.1 - 1.7e-23 83.6 0.0 1.2e-20 74.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ31332.1 - 8.1e-13 48.4 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF836 PF05768.14 OAJ31333.1 - 9.5e-10 38.8 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 OAJ31333.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Fcf1 PF04900.12 OAJ31334.1 - 5.1e-17 62.1 0.0 9.3e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Fcf1 mRNA_triPase PF02940.15 OAJ31335.1 - 8.3e-48 163.0 0.1 9.7e-48 162.8 0.1 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PH PF00169.29 OAJ31336.1 - 2.6e-14 53.6 0.0 8.6e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 PH domain SH3_9 PF14604.6 OAJ31336.1 - 3.9e-14 52.2 0.1 8.2e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ31336.1 - 4.9e-12 45.3 0.4 1.2e-11 44.1 0.4 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 OAJ31336.1 - 3.6e-09 36.2 0.0 8.2e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 OAJ31336.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 OAJ31336.1 - 0.00056 20.3 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 OAJ31336.1 - 0.22 11.8 0.3 0.45 10.8 0.3 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif BSP_II PF05432.11 OAJ31337.1 - 0.0029 17.4 21.9 0.0046 16.7 21.9 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 OAJ31337.1 - 0.039 13.7 20.3 0.068 12.9 20.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 OAJ31337.1 - 0.11 11.0 7.0 0.13 10.7 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PBP1_TM PF14812.6 OAJ31337.1 - 0.97 9.9 16.4 0.41 11.0 8.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1645 PF07816.11 OAJ31337.1 - 1.7 9.2 19.1 4.5 7.8 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) PI3K_1B_p101 PF10486.9 OAJ31337.1 - 2.1 6.0 10.1 0.066 11.0 2.0 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GOLD_2 PF13897.6 OAJ31337.1 - 2.8 8.4 13.0 2.4 8.7 3.4 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DNA_pol_phi PF04931.13 OAJ31337.1 - 4.6 5.2 24.8 0.54 8.3 14.4 2.0 2 0 0 2 2 2 0 DNA polymerase phi KGG PF10685.9 OAJ31338.1 - 8.7e-09 35.4 8.1 9.6e-07 28.9 0.2 4.0 2 1 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif SPX PF03105.19 OAJ31339.1 - 3.8e-34 119.2 8.5 1.7e-24 87.5 0.7 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 OAJ31339.1 - 3e-32 112.3 36.9 4.4e-32 111.7 36.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 OAJ31339.1 - 5.4e-32 111.2 59.7 3.5e-28 98.7 29.0 2.3 1 1 1 2 2 2 2 Citrate transporter DUF997 PF06196.12 OAJ31339.1 - 1.9 8.6 8.1 5.6 7.0 0.3 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DEAD PF00270.29 OAJ31341.1 - 1.6e-20 73.6 0.2 7.2e-20 71.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 OAJ31341.1 - 0.0058 16.6 0.0 0.1 12.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit FAM76 PF16046.5 OAJ31341.1 - 0.33 10.3 1.6 0.46 9.8 1.6 1.2 1 0 0 1 1 1 0 FAM76 protein Mito_fiss_reg PF05308.11 OAJ31341.1 - 1.5 8.8 5.9 0.28 11.2 2.3 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator HisKA PF00512.25 OAJ31341.1 - 1.6 8.8 4.0 1.4 9.0 1.1 2.1 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF4228 PF14009.6 OAJ31341.1 - 6.1 7.2 9.0 1.1 9.6 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4228) Metallophos PF00149.28 OAJ31342.1 - 2.5e-17 64.1 0.0 5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 OAJ31342.1 - 8.5e-12 45.5 0.9 3.3e-11 43.6 0.9 2.1 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 OAJ31342.1 - 3.9e-11 43.7 0.0 1.1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Helicase_C PF00271.31 OAJ31342.1 - 1.2e-10 41.7 0.1 2.3e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 OAJ31342.1 - 2.3e-08 34.6 0.0 5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RecQ zinc-binding fn3 PF00041.21 OAJ31342.1 - 0.0065 16.8 1.0 0.016 15.6 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain PhoD_N PF16655.5 OAJ31342.1 - 0.0075 16.8 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Mur_ligase_M PF08245.12 OAJ31343.1 - 0.0011 19.0 0.5 0.28 11.1 0.5 2.8 1 1 0 1 1 1 1 Mur ligase middle domain FtsJ PF01728.19 OAJ31344.1 - 2.5e-46 158.0 0.0 8e-36 123.8 0.0 2.0 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 OAJ31344.1 - 9.9e-05 23.0 0.0 0.00033 21.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31344.1 - 0.0038 17.0 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 OAJ31344.1 - 0.0045 16.6 0.1 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 OAJ31344.1 - 0.0058 16.5 0.0 0.019 14.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 OAJ31344.1 - 0.066 14.2 0.0 0.3 12.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ31344.1 - 0.17 12.7 0.0 0.39 11.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ31344.1 - 0.2 11.0 0.0 0.6 9.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family WD40 PF00400.32 OAJ31345.1 - 3.8e-36 122.5 15.6 7.4e-07 29.8 0.4 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ31345.1 - 3.7e-09 36.8 1.2 1.6 9.1 0.0 6.4 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 OAJ31345.1 - 4.6e-05 23.0 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 OAJ31345.1 - 0.011 14.7 0.5 1 8.2 0.0 3.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 OAJ31345.1 - 0.015 14.0 0.2 1.1 7.8 0.0 3.0 2 1 0 3 3 3 0 Nucleoporin Nup120/160 SUIM_assoc PF16619.5 OAJ31345.1 - 0.75 9.9 12.1 2.4 8.3 2.2 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NOA36 PF06524.12 OAJ31345.1 - 2.2 7.5 4.6 4.8 6.4 4.6 1.5 1 0 0 1 1 1 0 NOA36 protein EF-hand_6 PF13405.6 OAJ31346.1 - 4.9e-07 29.2 0.2 0.015 15.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 OAJ31346.1 - 6.3e-07 29.8 0.3 2.1e-06 28.1 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 OAJ31346.1 - 1.4e-06 27.5 0.0 0.014 14.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 OAJ31346.1 - 2.1e-05 23.7 0.2 0.13 11.8 0.0 2.8 2 0 0 2 2 2 2 EF hand OCRE PF17780.1 OAJ31346.1 - 0.051 13.6 0.5 0.11 12.5 0.5 1.6 1 0 0 1 1 1 0 OCRE domain SPARC_Ca_bdg PF10591.9 OAJ31346.1 - 0.31 11.4 4.7 3.1 8.1 0.0 3.7 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region ABC_ATPase PF09818.9 OAJ31347.1 - 2.8e-134 448.3 0.0 2.8e-133 445.0 0.0 2.0 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_28 PF13521.6 OAJ31347.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ31347.1 - 0.34 11.4 1.7 1.2 9.6 1.3 1.9 1 1 1 2 2 2 0 ABC transporter Cullin PF00888.22 OAJ31349.1 - 1.5e-139 466.5 0.0 2.8e-139 465.6 0.0 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 OAJ31349.1 - 2.5e-20 72.2 0.8 7.1e-20 70.8 0.8 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 OAJ31349.1 - 0.048 14.2 0.4 0.18 12.4 0.4 2.0 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal AAR2 PF05282.11 OAJ31350.1 - 1.4e-43 149.6 1.4 1.5e-43 149.5 0.4 1.5 1 1 1 2 2 2 1 AAR2 protein Sorting_nexin PF03700.13 OAJ31350.1 - 0.019 15.5 3.7 0.019 15.5 3.7 3.1 3 0 0 3 3 3 0 Sorting nexin, N-terminal domain BPA_C PF18040.1 OAJ31350.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 beta porphyranase A C-terminal MID_MedPIWI PF18296.1 OAJ31350.1 - 1.2 8.8 7.3 3.9 7.2 2.0 2.3 2 0 0 2 2 2 0 MID domain of medPIWI TFIIA PF03153.13 OAJ31350.1 - 1.8 8.5 13.3 0.17 11.9 2.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 OAJ31350.1 - 3.8 8.3 7.4 67 4.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 OAJ31351.1 - 3.2e-07 30.6 8.1 6.1e-07 29.7 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 OAJ31351.1 - 0.00072 19.8 5.6 0.0016 18.7 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 OAJ31351.1 - 0.0013 18.7 1.5 0.0031 17.5 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 OAJ31351.1 - 0.0058 16.8 3.7 0.013 15.6 3.7 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 OAJ31351.1 - 0.014 15.3 8.4 0.024 14.5 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 OAJ31351.1 - 0.021 14.9 6.1 0.05 13.7 6.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 OAJ31351.1 - 0.037 13.9 7.6 0.075 12.9 7.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_9 PF13901.6 OAJ31351.1 - 0.06 13.3 2.8 0.26 11.2 3.5 1.7 2 0 0 2 2 1 0 Putative zinc-RING and/or ribbon Phage_lysis PF03245.13 OAJ31351.1 - 0.12 12.5 0.4 0.91 9.7 0.1 2.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein C1_1 PF00130.22 OAJ31351.1 - 0.44 10.5 3.4 0.87 9.5 3.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4611 PF15387.6 OAJ31351.1 - 0.62 10.3 6.5 2 8.7 6.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) zf-RING-like PF08746.11 OAJ31351.1 - 0.94 9.8 5.1 1.8 9.0 5.1 1.5 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 OAJ31351.1 - 1 9.0 3.7 2 8.1 3.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CENP-B_dimeris PF09026.10 OAJ31351.1 - 1.5 9.2 8.6 4.9 7.6 8.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PHD PF00628.29 OAJ31351.1 - 2.4 8.1 5.2 4.4 7.3 5.2 1.4 1 0 0 1 1 1 0 PHD-finger Nkap_C PF06047.11 OAJ31352.1 - 2.4e-44 149.6 4.7 2.4e-44 149.6 4.7 1.9 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain Macoilin PF09726.9 OAJ31352.1 - 0.0023 16.6 10.9 0.0029 16.2 10.9 1.3 1 0 0 1 1 1 1 Macoilin family Ribosomal_L32p PF01783.23 OAJ31353.1 - 1.5e-14 54.0 6.7 3.7e-14 52.7 6.7 1.7 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 OAJ31353.1 - 0.011 15.6 1.2 0.022 14.7 1.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GcpE PF04551.14 OAJ31353.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 GcpE protein DUF1180 PF06679.12 OAJ31353.1 - 3.8 7.9 7.7 6.3 7.2 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) BTB PF00651.31 OAJ31354.1 - 7.4e-06 26.2 0.0 0.016 15.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Polyketide_cyc PF03364.20 OAJ31355.1 - 7.3e-23 81.2 0.2 1.8e-22 79.9 0.2 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 OAJ31355.1 - 0.00018 21.8 0.1 0.021 15.1 0.1 2.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Pheromone PF08015.11 OAJ31355.1 - 0.071 14.2 6.2 0.18 12.9 6.2 1.8 1 0 0 1 1 1 0 Fungal mating-type pheromone PAP1 PF08601.10 OAJ31355.1 - 0.35 10.5 5.5 0.41 10.3 5.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Myb_DNA-binding PF00249.31 OAJ31356.1 - 2.2e-13 50.2 0.1 3.4e-05 23.9 0.0 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ31356.1 - 4.8e-13 49.1 0.0 0.00023 21.3 0.0 4.3 3 1 1 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 OAJ31356.1 - 0.019 15.1 0.0 21 5.4 0.0 3.0 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 adh_short_C2 PF13561.6 OAJ31359.1 - 2.6e-46 158.1 6.1 5.5e-23 81.7 0.1 3.0 1 1 2 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ31359.1 - 5.9e-42 143.3 2.4 1.3e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 OAJ31359.1 - 3.9e-11 43.2 1.5 4.3e-05 23.5 0.1 2.6 2 1 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 OAJ31359.1 - 0.00038 20.4 0.4 0.00072 19.5 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ31359.1 - 0.021 14.9 0.1 0.046 13.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ31359.1 - 0.059 12.7 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 OAJ31359.1 - 0.1 13.3 0.1 0.22 12.3 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2007 PF09413.10 OAJ31359.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein E1-E2_ATPase PF00122.20 OAJ31360.1 - 5.2e-48 162.9 1.2 5.2e-48 162.9 1.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 OAJ31360.1 - 6.7e-46 156.3 4.7 3.3e-45 154.0 2.3 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 OAJ31360.1 - 4.9e-20 72.7 0.0 2.2e-06 28.1 0.2 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ31360.1 - 2.2e-17 62.5 0.0 4.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 OAJ31360.1 - 1e-15 57.6 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ31360.1 - 0.00024 20.9 1.7 0.0071 16.1 2.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 OAJ31360.1 - 0.078 13.4 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Translin PF01997.16 OAJ31361.1 - 5.6e-45 153.8 0.1 1.5e-33 116.5 0.0 2.2 1 1 1 2 2 2 2 Translin family Sterile PF03015.19 OAJ31361.1 - 0.11 12.8 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein DAO PF01266.24 OAJ31363.1 - 1.1e-42 146.9 1.5 8e-42 144.1 1.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 OAJ31363.1 - 6.8e-05 23.0 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 OAJ31363.1 - 0.024 13.9 0.1 0.075 12.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 OAJ31363.1 - 0.046 14.3 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 OAJ31363.1 - 0.065 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 OAJ31363.1 - 0.068 11.7 0.1 0.13 10.8 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) SnoaL_2 PF12680.7 OAJ31363.1 - 0.091 13.4 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain TrkA_N PF02254.18 OAJ31363.1 - 0.094 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain GDA1_CD39 PF01150.17 OAJ31364.1 - 2.6e-75 253.7 0.0 1.6e-58 198.4 0.0 3.0 3 0 0 3 3 3 3 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 OAJ31364.1 - 0.053 13.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family Vta1 PF04652.16 OAJ31365.1 - 2.5e-50 170.2 0.9 3.6e-50 169.7 0.3 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 OAJ31365.1 - 9e-12 44.5 2.2 9e-12 44.5 2.2 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain TPR_12 PF13424.6 OAJ31366.1 - 0.0051 17.1 13.5 3.1 8.1 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ31366.1 - 0.04 14.7 11.3 77 4.5 0.1 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ31366.1 - 0.085 13.0 8.7 2.2 8.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat E1_dh PF00676.20 OAJ31367.1 - 3e-85 285.8 0.0 3.7e-85 285.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ31367.1 - 0.23 10.7 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Gpr1_Fun34_YaaH PF01184.19 OAJ31368.1 - 4.6e-83 277.9 18.4 5.6e-83 277.6 18.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF155 PF02582.14 OAJ31369.1 - 1.1e-46 159.2 0.0 1.6e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Helo_like_N PF17111.5 OAJ31369.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Peptidase_S10 PF00450.22 OAJ31371.1 - 2.4e-71 241.3 0.1 3e-71 241.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase PLU-1 PF08429.11 OAJ31372.1 - 1.4e-47 162.6 1.7 2.3e-47 161.9 1.7 1.4 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 OAJ31372.1 - 2.8e-42 143.7 0.4 5.4e-42 142.8 0.4 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 OAJ31372.1 - 6.1e-22 77.3 45.2 1.8e-12 47.0 3.2 4.5 4 0 0 4 4 4 4 PHD-finger ARID PF01388.21 OAJ31372.1 - 3.6e-17 62.8 0.0 8.3e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 OAJ31372.1 - 9e-13 48.4 0.2 9e-13 48.4 0.2 2.9 3 0 0 3 3 3 1 C5HC2 zinc finger JmjN PF02375.17 OAJ31372.1 - 2.4e-12 46.6 1.1 4.9e-12 45.6 1.1 1.6 1 0 0 1 1 1 1 jmjN domain AAA PF00004.29 OAJ31373.1 - 5.3e-41 140.1 0.0 8.5e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ31373.1 - 1.2e-10 41.1 0.1 2.7e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 OAJ31373.1 - 1.8e-10 40.4 0.1 3.5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ31373.1 - 1.2e-05 25.6 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ31373.1 - 2.3e-05 23.7 0.0 6.1e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ31373.1 - 3.9e-05 23.9 0.4 0.033 14.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 OAJ31373.1 - 0.00043 20.7 0.4 0.0096 16.3 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 OAJ31373.1 - 0.00069 19.6 0.4 0.0059 16.6 0.3 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ31373.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 OAJ31373.1 - 0.0014 18.2 0.7 0.0044 16.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 OAJ31373.1 - 0.0051 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ31373.1 - 0.0054 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 OAJ31373.1 - 0.006 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 OAJ31373.1 - 0.0061 15.9 0.1 0.22 10.8 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_14 PF13173.6 OAJ31373.1 - 0.014 15.4 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 OAJ31373.1 - 0.023 14.3 0.6 2.6 7.6 0.1 2.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 OAJ31373.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 OAJ31373.1 - 0.043 13.0 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 OAJ31373.1 - 0.086 13.1 0.3 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 OAJ31373.1 - 0.09 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OAJ31373.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 OAJ31373.1 - 0.13 12.1 0.2 0.79 9.6 0.1 2.1 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 OAJ31373.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 OAJ31373.1 - 0.26 11.0 2.3 0.36 10.5 0.3 2.1 2 1 0 2 2 2 0 AAA domain Mis12 PF05859.12 OAJ31374.1 - 6.3e-25 87.8 0.4 1.3e-24 86.7 0.4 1.6 1 1 0 1 1 1 1 Mis12 protein Glyco_transf_28 PF03033.20 OAJ31374.1 - 0.14 12.2 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Myb_DNA-binding PF00249.31 OAJ31375.1 - 3.4e-16 59.1 0.0 1.8e-07 31.2 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ31375.1 - 7.4e-12 45.3 0.0 6.6e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Nop16 PF09420.10 OAJ31375.1 - 0.04 13.9 0.0 3.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 SLIDE PF09111.10 OAJ31375.1 - 0.25 11.4 0.0 6.3 6.9 0.0 2.2 2 0 0 2 2 2 0 SLIDE TIM PF00121.18 OAJ31376.1 - 2.1e-92 308.9 0.3 2.3e-92 308.8 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 OAJ31376.1 - 0.0075 15.8 0.2 0.094 12.2 0.0 2.0 1 1 1 2 2 2 1 CutC family MEDS PF14417.6 OAJ31376.1 - 0.052 13.4 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Cyclin_N PF00134.23 OAJ31377.1 - 2.8e-09 36.8 0.0 3e-07 30.2 0.0 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 OAJ31377.1 - 0.048 14.0 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain AT_hook PF02178.19 OAJ31378.1 - 0.82 9.7 12.5 1.6 8.9 5.4 2.6 2 0 0 2 2 2 0 AT hook motif RR_TM4-6 PF06459.12 OAJ31378.1 - 3.6 7.3 31.8 6.1 6.6 31.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 OAJ31378.1 - 4.9 6.7 27.7 11 5.5 27.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Caldesmon PF02029.15 OAJ31378.1 - 7.2 5.2 32.1 10 4.8 32.1 1.1 1 0 0 1 1 1 0 Caldesmon DUF3808 PF10300.9 OAJ31379.1 - 8.1e-82 275.4 0.0 2.2e-81 274.0 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 OAJ31379.1 - 2.1e-05 24.3 0.9 0.058 13.5 0.2 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ31379.1 - 0.00031 20.7 0.3 0.1 12.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ31379.1 - 0.0029 18.1 0.4 3.2 8.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ31379.1 - 0.077 13.7 0.1 4.5 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 OAJ31379.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family TPR_1 PF00515.28 OAJ31379.1 - 0.16 11.9 0.9 1.5 8.8 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TOH_N PF12549.8 OAJ31380.1 - 0.038 13.8 2.1 1.9e+02 2.1 0.0 4.7 5 0 0 5 5 5 0 Tyrosine hydroxylase N terminal PROCN PF08083.11 OAJ31382.1 - 3e-225 747.5 7.4 5.2e-225 746.7 7.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 OAJ31382.1 - 7.1e-126 418.4 0.5 1.3e-125 417.6 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 OAJ31382.1 - 5.2e-88 293.0 2.5 1.5e-87 291.5 2.5 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 OAJ31382.1 - 1.7e-82 274.8 2.9 1.7e-82 274.8 2.9 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 OAJ31382.1 - 1.4e-65 219.3 0.0 2.8e-65 218.4 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 OAJ31382.1 - 4.9e-45 151.8 0.1 1.2e-44 150.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 OAJ31382.1 - 1.7e-39 134.6 0.0 3.3e-39 133.6 0.0 1.5 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 OAJ31382.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2370 PF10176.9 OAJ31383.1 - 2e-68 230.4 0.0 7.2e-68 228.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF3611 PF12263.8 OAJ31383.1 - 0.055 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF202 PF02656.15 OAJ31383.1 - 0.4 11.1 4.6 0.26 11.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Plk4_PB1 PF18190.1 OAJ31384.1 - 0.089 13.0 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 LSM PF01423.22 OAJ31386.1 - 5.1e-16 58.1 0.1 6.1e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 OAJ31386.1 - 0.14 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain DUF3106 PF11304.8 OAJ31388.1 - 0.025 15.1 0.9 0.025 15.1 0.9 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3106) LRR_8 PF13855.6 OAJ31389.1 - 6e-09 35.5 17.3 9.1e-09 35.0 8.5 4.4 6 0 0 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 OAJ31389.1 - 8.5e-09 35.6 19.7 4.4e-06 27.0 1.6 5.6 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 OAJ31389.1 - 6.4e-05 22.5 3.0 0.086 12.3 1.8 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 OAJ31389.1 - 0.62 10.3 0.0 0.62 10.3 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Phage_integrase PF00589.22 OAJ31390.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.4 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_1 PF02899.17 OAJ31390.1 - 0.028 14.7 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain HIT PF01230.23 OAJ31391.1 - 4.4e-22 78.6 0.1 7.1e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 OAJ31391.1 - 1.1e-10 42.0 0.0 1.8e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 OAJ31391.1 - 4e-06 26.7 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 NGP1NT PF08153.12 OAJ31392.1 - 2.7e-46 156.9 0.0 6.7e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 OAJ31392.1 - 2e-16 60.1 0.0 1.5e-13 50.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 OAJ31392.1 - 0.00033 20.1 0.1 0.049 13.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.18 OAJ31392.1 - 0.00056 19.5 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 OAJ31392.1 - 0.0007 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Utp14 PF04615.13 OAJ31392.1 - 0.16 10.5 22.5 0.2 10.2 21.5 1.6 2 0 0 2 2 2 0 Utp14 protein Dynamin_N PF00350.23 OAJ31392.1 - 0.39 10.8 6.1 0.78 9.8 0.0 4.0 4 1 1 5 5 5 0 Dynamin family MSC PF09402.10 OAJ31393.1 - 4.2e-41 141.5 0.0 2.8e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Man1-Src1p-C-terminal domain TFIIA PF03153.13 OAJ31393.1 - 1.7 8.5 18.4 3.5 7.5 18.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 OAJ31394.1 - 0.0002 21.4 3.1 0.0005 20.1 3.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltrn_RNA_3 PF02598.17 OAJ31395.1 - 3e-96 322.3 0.0 3.7e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 OAJ31395.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 SpoU rRNA Methylase family PBP1_TM PF14812.6 OAJ31395.1 - 3.3 8.1 11.3 1 9.7 8.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bromodomain PF00439.25 OAJ31396.1 - 1.5e-24 85.9 0.2 2.9e-24 84.9 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 OAJ31396.1 - 9e-08 32.4 0.0 2.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ31396.1 - 3.2e-05 23.9 0.0 7.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 OAJ31396.1 - 0.00026 21.4 0.2 0.00052 20.4 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Linker_histone PF00538.19 OAJ31397.1 - 6.2e-21 74.6 0.1 6.2e-21 74.6 0.1 1.7 2 0 0 2 2 2 1 linker histone H1 and H5 family VIR_N PF15912.5 OAJ31397.1 - 0.57 9.7 12.3 1.1 8.8 12.3 1.4 1 1 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 OAJ31397.1 - 2.4 6.9 4.6 3 6.6 4.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Striatin PF08232.12 OAJ31397.1 - 3 8.4 13.6 13 6.3 8.7 2.1 2 0 0 2 2 2 0 Striatin family ICMT PF04140.14 OAJ31398.1 - 3.6e-27 94.6 0.2 6.4e-27 93.8 0.2 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 OAJ31398.1 - 5.2e-11 42.9 1.7 1.4e-10 41.5 1.7 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 OAJ31398.1 - 9.8e-05 22.0 0.2 0.00014 21.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 OAJ31398.1 - 0.0052 15.6 0.2 0.0093 14.8 0.2 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family NnrU PF07298.11 OAJ31398.1 - 0.0062 16.1 1.4 0.0069 15.9 0.2 1.7 2 0 0 2 2 2 1 NnrU protein RRP7 PF12923.7 OAJ31399.1 - 0.023 14.8 0.5 0.044 13.9 0.5 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain SUIM_assoc PF16619.5 OAJ31400.1 - 0.092 12.8 4.4 3.7 7.7 2.8 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Clat_adaptor_s PF01217.20 OAJ31401.1 - 6.4e-20 71.5 0.8 8.6e-20 71.1 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mlh1_C PF16413.5 OAJ31402.1 - 9.2e-68 228.5 0.0 2.2e-66 224.0 0.0 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 OAJ31402.1 - 4.3e-31 107.1 0.0 7e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 OAJ31402.1 - 1.5e-12 47.5 0.0 6.7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ31402.1 - 5.1e-08 33.4 0.0 8.6e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YL1 PF05764.13 OAJ31402.1 - 8.8e-05 22.7 20.0 0.00017 21.8 20.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 OAJ31402.1 - 0.00065 18.1 18.6 0.00094 17.5 18.6 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 OAJ31402.1 - 0.0019 17.7 18.6 0.0033 16.9 18.6 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 OAJ31402.1 - 0.0049 15.2 16.6 0.01 14.2 16.6 1.4 1 0 0 1 1 1 1 CDC45-like protein PPP4R2 PF09184.11 OAJ31402.1 - 0.014 15.0 21.0 0.023 14.3 21.0 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 OAJ31402.1 - 0.049 13.0 23.8 0.094 12.0 23.8 1.4 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 OAJ31402.1 - 0.082 12.2 20.5 0.19 11.0 20.5 1.6 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 OAJ31402.1 - 0.13 12.0 19.0 0.23 11.2 19.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpp10 PF04006.12 OAJ31402.1 - 0.13 10.7 21.6 0.2 10.1 21.6 1.2 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 OAJ31402.1 - 0.45 8.2 2.9 0.65 7.7 2.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 OAJ31402.1 - 1.2 7.6 24.8 2.2 6.8 24.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vfa1 PF08432.10 OAJ31402.1 - 1.2 9.4 8.6 2.3 8.5 8.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 OAJ31402.1 - 4.2 7.3 10.9 8.2 6.3 10.9 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC27 PF09507.10 OAJ31402.1 - 4.5 6.6 18.3 7.1 5.9 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_phi PF04931.13 OAJ31402.1 - 5.2 5.0 42.4 7.7 4.5 42.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 OAJ31402.1 - 6.2 6.6 10.6 9.9 5.9 10.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SGT1 PF07093.11 OAJ31402.1 - 7.3 4.9 12.9 12 4.1 12.9 1.3 1 0 0 1 1 1 0 SGT1 protein Pyr_redox_2 PF07992.14 OAJ31403.1 - 0.034 13.4 0.1 0.35 10.1 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DCP1 PF06058.13 OAJ31404.1 - 3.7e-24 84.9 0.0 5.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family adh_short PF00106.25 OAJ31405.1 - 3.5e-13 49.5 0.4 6.1e-11 42.1 0.2 3.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ31405.1 - 7e-09 35.6 0.3 2.3e-07 30.6 0.1 2.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 OAJ31405.1 - 0.00016 21.6 0.2 0.00026 20.9 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 OAJ31405.1 - 0.0026 18.3 1.8 0.0077 16.8 0.6 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 OAJ31405.1 - 0.0041 17.0 0.1 0.0067 16.4 0.1 1.3 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 OAJ31405.1 - 0.011 15.7 0.1 0.052 13.5 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase ApbA PF02558.16 OAJ31405.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 OAJ31405.1 - 0.13 12.3 0.5 0.95 9.5 0.2 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase CsbD PF05532.12 OAJ31407.1 - 5.4e-18 64.6 16.5 1.4e-09 37.7 4.9 2.0 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 OAJ31407.1 - 0.0026 18.1 1.0 0.005 17.2 0.8 1.6 1 1 0 1 1 1 1 Heat shock protein 9/12 UCH PF00443.29 OAJ31408.1 - 2.9e-56 190.8 0.0 3.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ31408.1 - 4.5e-32 111.9 0.0 6.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 OAJ31408.1 - 0.00022 20.8 0.9 0.039 13.4 1.3 2.4 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase CCDC24 PF15669.5 OAJ31408.1 - 0.27 11.1 1.5 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DDE_Tnp_4 PF13359.6 OAJ31409.1 - 2.3e-24 85.9 0.0 3.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease YrbL-PhoP_reg PF10707.9 OAJ31409.1 - 1e-05 25.2 0.0 2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DDE_Tnp_1 PF01609.21 OAJ31409.1 - 0.091 12.4 4.7 0.11 12.1 0.0 2.9 2 1 0 2 2 2 0 Transposase DDE domain RT_RNaseH PF17917.1 OAJ31411.1 - 9e-07 29.1 0.3 4.3e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ31411.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase His_Phos_2 PF00328.22 OAJ31412.1 - 5.4e-30 105.0 0.0 6.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aminotran_MocR PF12897.7 OAJ31412.1 - 0.058 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase zf-FCS PF06467.14 OAJ31414.1 - 0.048 13.6 3.8 0.1 12.6 3.8 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF4604 PF15377.6 OAJ31415.1 - 2.5e-19 70.4 22.6 2.9e-19 70.1 22.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF572 PF04502.13 OAJ31415.1 - 1.3 8.6 16.0 1.6 8.2 16.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.13 OAJ31415.1 - 7.1 6.5 21.3 9.4 6.1 21.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_DNAp_acc PF04929.12 OAJ31415.1 - 9.6 5.1 10.9 1.1 8.1 6.4 1.6 2 0 0 2 2 2 0 Herpes DNA replication accessory factor ATP-synt_ab PF00006.25 OAJ31416.1 - 1.8e-67 227.1 0.0 2.5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 OAJ31416.1 - 6e-13 49.1 0.2 1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF561 PF04481.12 OAJ31416.1 - 0.056 12.6 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Cellulase PF00150.18 OAJ31417.1 - 5.9e-06 25.9 0.1 8.3e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADIP PF11559.8 OAJ31420.1 - 0.0089 16.1 3.6 0.0089 16.1 3.6 1.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 OAJ31420.1 - 0.011 14.6 5.1 0.015 14.2 5.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 OAJ31420.1 - 0.065 12.6 3.3 0.081 12.3 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 OAJ31420.1 - 0.073 11.7 0.2 0.092 11.3 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Filament PF00038.21 OAJ31420.1 - 0.092 12.3 6.0 0.12 11.9 6.0 1.0 1 0 0 1 1 1 0 Intermediate filament protein CHDCT2 PF08074.11 OAJ31420.1 - 0.25 11.5 1.9 0.35 11.0 1.9 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain SPATA24 PF15175.6 OAJ31420.1 - 0.92 9.4 4.8 7.4 6.4 0.7 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Striatin PF08232.12 OAJ31421.1 - 5e-20 72.7 1.5 2.3e-13 51.0 0.3 2.4 1 1 1 2 2 2 2 Striatin family G-alpha PF00503.20 OAJ31421.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Kelch_4 PF13418.6 OAJ31422.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ31422.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Myosin_head PF00063.21 OAJ31424.1 - 1.2e-238 793.8 2.5 1.4e-238 793.5 2.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 OAJ31424.1 - 4e-49 166.8 0.0 6.2e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 OAJ31424.1 - 4e-10 39.1 0.2 8.4e-10 38.1 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ31424.1 - 1.7e-09 37.4 0.1 4.3e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ31424.1 - 0.00013 21.5 0.0 0.00043 19.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 OAJ31424.1 - 0.0023 18.2 0.7 0.0054 17.0 0.7 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 OAJ31424.1 - 0.062 12.8 0.5 9.3 5.7 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 OAJ31424.1 - 0.062 13.7 0.0 0.2 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 OAJ31424.1 - 0.062 13.6 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 OAJ31424.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 OAJ31424.1 - 0.21 11.5 0.2 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 NACHT domain MIT PF04212.18 OAJ31425.1 - 7.4e-08 32.3 0.1 1.5e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Sugar_tr PF00083.24 OAJ31427.1 - 3e-118 395.5 13.5 3.9e-118 395.2 13.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ31427.1 - 5e-27 94.8 43.7 9.2e-26 90.6 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.6 OAJ31427.1 - 0.25 11.4 1.5 0.56 10.2 1.5 1.5 1 0 0 1 1 1 0 CoA-binding domain OATP PF03137.20 OAJ31427.1 - 3.8 5.7 7.1 6.5 4.9 2.1 2.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NUFIP1 PF10453.9 OAJ31428.1 - 5e-10 39.1 0.5 1.3e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) NPR3 PF03666.13 OAJ31428.1 - 6.5 5.4 10.6 11 4.6 10.6 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 OAJ31428.1 - 8.5 4.5 16.4 13 4.0 16.4 1.2 1 0 0 1 1 1 0 CDC45-like protein PLDc_2 PF13091.6 OAJ31429.1 - 4.7e-13 49.2 0.0 3.2e-06 27.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 OAJ31429.1 - 5.8e-06 26.3 3.5 0.063 13.5 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif 3Beta_HSD PF01073.19 OAJ31430.1 - 6.8e-60 202.4 0.0 1.4e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 OAJ31430.1 - 1.9e-23 83.2 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ31430.1 - 1.4e-10 41.1 0.0 4.4e-08 32.9 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 OAJ31430.1 - 2.1e-09 37.5 0.0 3.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 OAJ31430.1 - 8.1e-09 35.0 0.1 6.1e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 OAJ31430.1 - 8.3e-05 21.8 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 OAJ31430.1 - 0.00072 19.5 0.1 0.0053 16.7 0.1 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 OAJ31430.1 - 0.0058 15.8 0.1 0.028 13.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 OAJ31430.1 - 0.0064 16.7 0.0 0.017 15.4 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 OAJ31430.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family UBA_3 PF09288.10 OAJ31430.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DNA_pol_B_exo1 PF03104.19 OAJ31430.1 - 0.26 10.4 0.0 0.39 9.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Pribosyltran PF00156.27 OAJ31431.1 - 2.6e-08 33.6 0.1 6.4e-08 32.3 0.1 1.7 1 1 1 2 2 2 1 Phosphoribosyl transferase domain DHOase PF12890.7 OAJ31431.1 - 0.087 12.7 0.0 0.6 10.0 0.0 2.0 1 1 1 2 2 2 0 Dihydro-orotase-like Cofilin_ADF PF00241.20 OAJ31432.1 - 1.6e-18 66.7 0.0 1e-08 35.0 0.0 2.7 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Secretin_N PF03958.17 OAJ31432.1 - 0.041 14.3 6.3 0.52 10.8 0.0 3.9 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF2040 PF09745.9 OAJ31433.1 - 8.1e-32 109.8 20.2 8.1e-32 109.8 20.2 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) AAA PF00004.29 OAJ31435.1 - 3.5e-84 279.9 0.0 1.6e-41 141.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ31435.1 - 1.3e-25 88.9 3.7 1.1e-11 44.4 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 OAJ31435.1 - 4.4e-14 52.7 0.1 3.9e-06 26.9 0.0 4.8 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 OAJ31435.1 - 2.1e-13 50.3 0.0 4.8e-06 26.4 0.0 3.2 4 0 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 OAJ31435.1 - 3.5e-13 50.3 2.4 6e-07 30.0 0.4 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ31435.1 - 4e-09 36.8 0.6 0.0016 18.7 0.1 4.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ31435.1 - 8.1e-08 31.9 0.1 0.00055 19.2 0.0 2.6 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_25 PF13481.6 OAJ31435.1 - 2.1e-07 30.7 4.9 0.067 12.8 0.1 4.7 3 2 1 4 4 4 2 AAA domain AAA_33 PF13671.6 OAJ31435.1 - 1.2e-06 28.7 0.0 0.013 15.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 OAJ31435.1 - 1.3e-06 28.6 0.0 0.052 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 OAJ31435.1 - 5.2e-06 26.5 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ31435.1 - 6.8e-06 25.9 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 OAJ31435.1 - 1.1e-05 25.4 0.1 0.063 13.2 0.0 3.4 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_18 PF13238.6 OAJ31435.1 - 3.1e-05 24.5 0.0 0.012 16.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 OAJ31435.1 - 3.2e-05 24.3 0.0 0.39 11.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 OAJ31435.1 - 3.7e-05 23.2 2.7 0.096 12.1 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 OAJ31435.1 - 0.00011 22.5 0.0 0.17 12.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 OAJ31435.1 - 0.00019 21.0 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 OAJ31435.1 - 0.00021 21.1 0.0 0.0098 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ31435.1 - 0.00074 18.8 0.0 0.058 12.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 OAJ31435.1 - 0.0019 18.2 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 OAJ31435.1 - 0.0031 17.5 0.1 4.7 7.1 0.0 3.2 2 1 0 2 2 2 1 NACHT domain ATPase PF06745.13 OAJ31435.1 - 0.0038 16.6 0.0 2.2 7.6 0.0 3.0 4 0 0 4 4 3 1 KaiC AAA_3 PF07726.11 OAJ31435.1 - 0.0039 17.1 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 OAJ31435.1 - 0.005 17.3 0.1 4.1 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 OAJ31435.1 - 0.0085 15.8 0.1 7.5 6.2 0.0 3.8 3 1 0 3 3 3 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 OAJ31435.1 - 0.0089 16.1 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 OAJ31435.1 - 0.011 16.2 0.0 0.88 10.1 0.0 3.0 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 OAJ31435.1 - 0.017 15.0 0.7 1.3 8.9 0.0 3.6 3 2 1 5 5 4 0 NTPase AAA_11 PF13086.6 OAJ31435.1 - 0.022 14.5 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ31435.1 - 0.027 13.9 0.4 0.79 9.1 0.1 2.5 3 0 0 3 3 2 0 PhoH-like protein Parvo_NS1 PF01057.17 OAJ31435.1 - 0.027 13.5 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 OAJ31435.1 - 0.038 13.7 0.0 0.67 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 OAJ31435.1 - 0.048 14.0 0.3 0.99 9.7 0.2 2.8 2 1 1 3 3 2 0 AAA domain PduV-EutP PF10662.9 OAJ31435.1 - 0.14 11.9 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 OAJ31435.1 - 0.17 11.0 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Peptidase_M13_N PF05649.13 OAJ31436.1 - 2.6e-85 287.4 0.0 3.4e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 OAJ31436.1 - 4.5e-57 193.0 0.0 7.9e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF4164 PF13747.6 OAJ31436.1 - 0.4 11.0 2.2 0.46 10.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) GATA PF00320.27 OAJ31437.1 - 1.1e-12 47.4 5.7 2e-12 46.5 5.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF543 PF04418.12 OAJ31438.1 - 6.9e-29 99.7 0.2 1.8e-28 98.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF4536 PF15055.6 OAJ31438.1 - 9.7e-06 25.7 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF883 PF05957.13 OAJ31438.1 - 0.26 11.9 3.3 5 7.8 0.2 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) MeaB PF03308.16 OAJ31439.1 - 5.1e-06 25.7 0.1 8.2e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 OAJ31439.1 - 0.0001 22.7 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 OAJ31439.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 OAJ31439.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 OAJ31439.1 - 0.0023 17.8 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 OAJ31439.1 - 0.0034 16.6 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 OAJ31439.1 - 0.0045 17.3 0.0 0.0094 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 OAJ31439.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 OAJ31439.1 - 0.006 15.9 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain DUF815 PF05673.13 OAJ31439.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 OAJ31439.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 OAJ31439.1 - 0.026 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ31439.1 - 0.047 14.2 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 OAJ31439.1 - 0.049 13.6 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 OAJ31439.1 - 0.071 13.7 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 OAJ31439.1 - 0.074 12.9 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 OAJ31439.1 - 0.077 13.4 0.1 0.32 11.4 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 OAJ31439.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_35 PF14516.6 OAJ31439.1 - 0.089 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 OAJ31439.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ31439.1 - 0.15 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ31439.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-rbx1 PF12678.7 OAJ31440.1 - 2.9e-06 27.5 3.8 6.4e-06 26.4 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ31440.1 - 3.6e-06 27.2 4.3 3.6e-06 27.2 4.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 OAJ31440.1 - 2.5e-05 24.0 3.3 2.5e-05 24.0 3.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ31440.1 - 0.0015 18.4 2.8 0.0015 18.4 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ31440.1 - 0.0018 18.1 1.7 0.0018 18.1 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 OAJ31440.1 - 0.0097 15.5 5.7 0.022 14.4 5.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 OAJ31440.1 - 0.013 15.5 2.5 0.013 15.5 2.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 OAJ31440.1 - 0.019 15.0 1.0 0.05 13.7 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 OAJ31440.1 - 2.1 8.4 4.7 1.5 8.9 1.9 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 OAJ31440.1 - 8.8 6.3 11.4 0.038 13.9 2.5 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Putative_PNPOx PF01243.20 OAJ31441.1 - 0.00046 20.3 0.0 0.16 12.1 0.0 3.2 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase MIF4G PF02854.19 OAJ31442.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain EAR PF07897.11 OAJ31442.1 - 0.69 9.6 3.7 1.6 8.4 1.0 2.4 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression OTU PF02338.19 OAJ31443.1 - 1.2e-24 87.3 0.0 2.2e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAJ31443.1 - 0.025 14.0 0.0 3 7.2 0.0 2.4 2 1 0 2 2 2 0 Peptidase C65 Otubain Halo_GVPC PF05465.13 OAJ31443.1 - 0.8 10.0 0.0 0.8 10.0 0.0 2.5 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3618 PF12277.8 OAJ31443.1 - 0.95 9.8 8.9 0.66 10.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DPBB_1 PF03330.18 OAJ31444.1 - 4.8e-09 36.4 0.1 8.8e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Promethin PF16015.5 OAJ31445.1 - 0.82 9.6 7.6 3 7.8 0.2 3.4 3 0 0 3 3 3 0 Promethin Glyco_hydro_cc PF11790.8 OAJ31446.1 - 9e-38 130.2 0.1 1.2e-37 129.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Neur_chan_memb PF02932.16 OAJ31446.1 - 3.5 7.6 4.4 6 6.8 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.9 OAJ31446.1 - 4 5.9 13.2 5.9 5.3 13.2 1.1 1 0 0 1 1 1 0 Macoilin family Connexin PF00029.19 OAJ31446.1 - 4.9 6.8 6.6 8.4 6.1 6.6 1.4 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 OAJ31446.1 - 7.3 4.4 6.6 11 3.7 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 OAJ31446.1 - 9 5.2 9.1 5 6.0 4.0 2.0 2 0 0 2 2 2 0 Solute carrier family 12 Epimerase PF01370.21 OAJ31447.1 - 1.4e-05 24.7 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 OAJ31447.1 - 0.00089 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 OAJ31447.1 - 0.0031 17.8 0.0 0.0064 16.7 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 OAJ31447.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Glyco_tran_WecB PF03808.13 OAJ31447.1 - 0.03 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family GDP_Man_Dehyd PF16363.5 OAJ31447.1 - 0.094 12.1 0.0 1 8.7 0.0 2.4 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 OAJ31447.1 - 0.15 11.9 0.2 0.38 10.6 0.0 1.7 1 1 1 2 2 2 0 KR domain DMAP1 PF05499.12 OAJ31448.1 - 0.38 10.6 3.7 0.21 11.4 1.7 1.5 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Zn_clus PF00172.18 OAJ31449.1 - 4.6e-07 29.8 8.6 9.8e-07 28.8 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGAP PF00620.27 OAJ31451.1 - 1.5e-35 122.2 0.0 2.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain HTH_Tnp_Tc5 PF03221.16 OAJ31453.1 - 3.4e-05 23.8 0.1 0.00035 20.6 0.0 2.3 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain Pro_CA PF00484.19 OAJ31455.1 - 7e-35 120.6 0.1 1.7e-34 119.4 0.1 1.6 1 0 0 1 1 1 1 Carbonic anhydrase Phospholip_A2_2 PF05826.12 OAJ31455.1 - 0.088 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Phospholipase A2 AAA_12 PF13087.6 OAJ31456.1 - 2.9e-32 111.9 0.0 4.7e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ31456.1 - 2.4e-28 99.7 1.8 9.6e-27 94.4 1.8 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ31456.1 - 7.5e-09 36.1 0.0 1.2e-07 32.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ31456.1 - 1.8e-07 31.1 0.1 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 OAJ31456.1 - 0.00025 20.4 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 OAJ31456.1 - 0.00056 20.0 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 OAJ31456.1 - 0.00063 19.6 0.1 2.2 7.9 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 OAJ31456.1 - 0.012 15.1 0.0 0.93 8.9 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF745 PF05335.13 OAJ31456.1 - 0.043 13.5 6.2 0.02 14.6 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) UvrD_C_2 PF13538.6 OAJ31456.1 - 0.091 12.6 0.0 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain F5_F8_type_C PF00754.25 OAJ31456.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 F5/8 type C domain AAA_22 PF13401.6 OAJ31456.1 - 0.17 12.1 0.4 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain ADH_N PF08240.12 OAJ31458.1 - 2.1e-26 91.9 2.0 5.7e-26 90.5 2.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ31458.1 - 1.9e-22 79.7 0.2 3.2e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.21 OAJ31458.1 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat AlaDh_PNT_C PF01262.21 OAJ31458.1 - 0.0078 15.5 0.2 0.013 14.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 OAJ31458.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Cytochrome_C7 PF14522.6 OAJ31459.1 - 0.12 12.3 1.7 0.26 11.3 1.7 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Myb_DNA-bind_3 PF12776.7 OAJ31460.1 - 7.3e-05 23.7 1.7 0.0073 17.3 0.1 2.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Fibrillarin_2 PF10113.9 OAJ31460.1 - 0.093 11.3 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein TFIIA PF03153.13 OAJ31460.1 - 0.28 11.1 32.2 0.19 11.7 20.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAPS_reduct PF01507.19 OAJ31462.1 - 1.5e-36 126.1 0.0 1.9e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family VPS28 PF03997.12 OAJ31465.1 - 3.6e-58 196.4 0.0 5.8e-58 195.7 0.0 1.3 1 1 0 1 1 1 1 VPS28 protein NA37 PF04245.13 OAJ31466.1 - 0.035 13.6 1.4 0.053 13.0 1.4 1.2 1 0 0 1 1 1 0 37-kD nucleoid-associated bacterial protein X PF00739.19 OAJ31466.1 - 4.5 7.4 5.6 8.4 6.5 5.6 1.5 1 0 0 1 1 1 0 Trans-activation protein X Phage_holin_3_6 PF07332.11 OAJ31467.1 - 0.018 15.1 2.3 0.45 10.6 0.1 3.2 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III MscS_TM PF12794.7 OAJ31467.1 - 0.7 8.7 5.1 13 4.5 3.4 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Pkinase PF00069.25 OAJ31468.1 - 2.9e-39 135.0 0.0 7.5e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31468.1 - 1.4e-23 83.5 0.0 2.1e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ31468.1 - 1e-07 31.1 0.0 2.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase ATP-synt_C PF00137.21 OAJ31468.1 - 0.15 12.4 4.7 0.3 11.5 4.7 1.4 1 0 0 1 1 1 0 ATP synthase subunit C TPR_2 PF07719.17 OAJ31469.1 - 0.01 15.9 0.1 13 6.2 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ31469.1 - 0.073 13.4 4.7 1.3 9.4 1.0 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat AAA_10 PF12846.7 OAJ31469.1 - 0.28 10.1 3.7 0.87 8.4 0.4 2.2 2 0 0 2 2 2 0 AAA-like domain Nbl1_Borealin_N PF10444.9 OAJ31469.1 - 0.53 10.0 3.0 1.7 8.3 0.2 3.0 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF4439 PF14530.6 OAJ31469.1 - 2.9 8.6 8.2 0.57 10.9 3.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4439) F1F0-ATPsyn_F PF10791.9 OAJ31470.1 - 2e-28 98.7 0.0 2.6e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Hexapep PF00132.24 OAJ31471.1 - 5.9e-11 41.7 5.8 2.4e-06 27.1 1.2 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ31471.1 - 6.9e-06 25.7 3.5 0.12 12.1 0.0 3.2 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 OAJ31471.1 - 0.2 10.5 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase Polysacc_synt_4 PF04669.13 OAJ31472.1 - 2.2e-19 69.7 3.1 9.9e-18 64.4 3.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis NDUF_B12 PF08122.12 OAJ31473.1 - 1.4e-16 60.2 0.2 2.1e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Transp_cyt_pur PF02133.15 OAJ31474.1 - 7.9e-129 430.3 42.5 2e-121 405.8 33.8 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin adh_short PF00106.25 OAJ31475.1 - 2e-45 154.7 1.2 2.8e-45 154.2 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ31475.1 - 3.3e-28 98.8 1.3 4.4e-28 98.4 1.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 OAJ31475.1 - 2.7e-05 23.7 0.1 5.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 OAJ31475.1 - 0.00014 21.8 0.2 0.00035 20.5 0.2 1.7 1 1 0 1 1 1 1 KR domain Peroxidase_2 PF01328.17 OAJ31476.1 - 3.5e-42 145.1 0.0 5e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 G-patch_2 PF12656.7 OAJ31477.1 - 3.7e-22 78.2 1.3 3.7e-22 78.2 1.3 2.7 3 0 0 3 3 3 1 G-patch domain G-patch PF01585.23 OAJ31477.1 - 7.1e-06 25.8 3.7 1.5e-05 24.8 3.7 1.5 1 0 0 1 1 1 1 G-patch domain Redoxin PF08534.10 OAJ31478.1 - 4.2e-29 101.1 0.1 4.9e-29 100.9 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ31478.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Glycos_transf_2 PF00535.26 OAJ31479.1 - 4.5e-31 107.9 0.0 5.8e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 OAJ31479.1 - 1.4e-11 44.7 0.0 2.6e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 OAJ31479.1 - 0.0011 18.5 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 OAJ31479.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 OAJ31479.1 - 0.0087 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 DUF4799 PF16056.5 OAJ31479.1 - 0.087 12.0 0.4 0.13 11.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) HCNGP PF07818.13 OAJ31480.1 - 1.1e-21 77.3 0.0 2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 HCNGP-like protein PRP38_assoc PF12871.7 OAJ31480.1 - 0.0012 19.4 23.8 0.0012 19.4 23.8 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paramyxo_ncap PF00973.19 OAJ31480.1 - 0.15 10.9 9.0 0.25 10.2 9.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3915 PF13054.6 OAJ31480.1 - 6.4 6.8 8.5 15 5.6 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FAM220 PF15487.6 OAJ31480.1 - 7.3 6.1 11.0 0.096 12.3 1.7 2.2 2 1 0 2 2 2 0 FAM220 family Cwf_Cwc_15 PF04889.12 OAJ31482.1 - 0.014 15.2 21.9 0.024 14.4 21.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3c_N PF05470.12 OAJ31482.1 - 0.54 8.5 13.1 0.69 8.1 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus MFAP1 PF06991.11 OAJ31482.1 - 0.72 9.7 18.5 1.1 9.1 18.5 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TFIIF_alpha PF05793.12 OAJ31482.1 - 0.86 8.1 23.5 1.2 7.6 23.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 OAJ31482.1 - 5.2 5.0 28.8 6.9 4.6 28.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 OAJ31482.1 - 9.3 4.7 21.2 13 4.2 21.2 1.2 1 0 0 1 1 1 0 Utp14 protein BUD22 PF09073.10 OAJ31482.1 - 9.6 5.4 24.5 13 5.0 24.5 1.1 1 0 0 1 1 1 0 BUD22 K_channel_TID PF07941.11 OAJ31483.1 - 0.86 10.1 9.2 0.84 10.1 8.7 1.4 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Integrase_H2C2 PF17921.1 OAJ31486.1 - 9.1e-16 57.7 0.0 1.9e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 OAJ31486.1 - 3.7e-13 49.7 0.0 2.1e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH_2 PF17919.1 OAJ31486.1 - 5.3e-13 48.9 0.1 1.4e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ31486.1 - 0.089 13.1 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ31487.1 - 2.8e-12 46.8 0.0 4.8e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 OAJ31487.1 - 3e-06 27.2 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ProQ_C PF17516.2 OAJ31487.1 - 0.03 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 ProQ C-terminal domain Med13_C PF06333.12 OAJ31488.1 - 8.9e-21 74.5 4.4 8.9e-21 74.5 4.4 3.7 4 1 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain RNA_pol_L_2 PF13656.6 OAJ31489.1 - 1.3e-27 95.3 0.0 2.1e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ31489.1 - 2.1e-07 30.2 0.0 3.3e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.6 OAJ31489.1 - 0.0026 15.8 0.0 0.0034 15.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial-associated sphingomyelin phosphodiesterase Lyase_1 PF00206.20 OAJ31490.1 - 5.3e-22 78.6 0.0 8.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 OAJ31490.1 - 3.5e-17 62.7 0.0 9.6e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus M20_dimer PF07687.14 OAJ31491.1 - 1.9e-09 37.4 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 OAJ31491.1 - 2.1e-05 24.3 0.3 4e-05 23.4 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 NKWYS PF10364.9 OAJ31491.1 - 0.076 13.1 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein IMUP PF15761.5 OAJ31492.1 - 0.052 14.2 5.7 0.066 13.9 5.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 OAJ31492.1 - 0.08 12.5 8.4 0.1 12.2 8.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hamartin PF04388.12 OAJ31492.1 - 1.1 7.8 5.1 1.2 7.7 5.1 1.0 1 0 0 1 1 1 0 Hamartin protein Med3 PF11593.8 OAJ31492.1 - 3.6 6.7 13.0 4.2 6.5 13.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CH PF00307.31 OAJ31493.1 - 1.5e-46 157.1 0.1 6e-24 84.3 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 OAJ31493.1 - 6.3e-19 67.8 0.0 1.8e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 OAJ31493.1 - 1.2e-11 44.3 0.1 3.6e-07 29.9 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain DUF1664 PF07889.12 OAJ31493.1 - 0.074 13.1 0.5 0.17 11.9 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EF-hand_6 PF13405.6 OAJ31493.1 - 0.12 12.4 0.0 0.75 9.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Spc7 PF08317.11 OAJ31493.1 - 0.14 11.0 4.2 0.22 10.4 4.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 OAJ31493.1 - 0.2 11.2 5.8 0.37 10.3 5.8 1.4 1 0 0 1 1 1 0 PspA/IM30 family FAM76 PF16046.5 OAJ31493.1 - 0.36 10.2 0.8 0.55 9.5 0.8 1.2 1 0 0 1 1 1 0 FAM76 protein Spectrin PF00435.21 OAJ31493.1 - 0.51 10.8 5.4 2.3 8.8 0.9 3.1 2 1 0 2 2 2 0 Spectrin repeat Baculo_PEP_C PF04513.12 OAJ31493.1 - 0.73 9.9 3.7 0.42 10.7 0.3 2.2 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HIP1_clath_bdg PF16515.5 OAJ31493.1 - 1.1 9.9 4.7 0.61 10.7 1.9 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cse1 PF08506.10 OAJ31494.1 - 3.7e-19 68.8 0.0 4.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 OAJ31494.1 - 1.9e-10 40.5 1.4 6.3e-08 32.4 0.2 3.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 OAJ31494.1 - 0.019 15.0 0.1 0.081 13.0 0.1 2.0 1 1 1 2 2 2 0 Exportin 1-like protein DUF1840 PF08895.11 OAJ31494.1 - 0.039 14.3 0.1 0.97 9.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Spt20 PF12090.8 OAJ31495.1 - 0.72 9.4 8.6 0.76 9.4 6.2 1.9 2 0 0 2 2 2 0 Spt20 family DASH_Spc34 PF08657.10 OAJ31495.1 - 0.92 9.2 4.5 17 5.1 0.2 3.1 2 1 1 3 3 3 0 DASH complex subunit Spc34 Spt5_N PF11942.8 OAJ31495.1 - 2.6 9.1 6.4 3 8.9 1.2 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DivIC PF04977.15 OAJ31495.1 - 3.5 7.5 9.0 24 4.8 0.4 3.3 3 0 0 3 3 3 0 Septum formation initiator NUC153 PF08159.12 OAJ31496.1 - 6e-11 42.0 0.3 1e-10 41.2 0.3 1.4 1 0 0 1 1 1 1 NUC153 domain Nop14 PF04147.12 OAJ31496.1 - 0.4 8.8 18.8 0.57 8.3 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 OAJ31496.1 - 4.5 7.2 12.7 7.2 6.5 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpb4 PF03874.16 OAJ31497.1 - 6.3e-12 45.9 0.2 1e-11 45.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 AKAP2_C PF15304.6 OAJ31497.1 - 0.19 11.0 0.9 0.24 10.7 0.9 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus NAD_binding_5 PF07994.12 OAJ31498.1 - 3.7e-141 470.2 0.0 5.2e-141 469.7 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 OAJ31498.1 - 4.6e-42 142.7 0.1 8.2e-42 141.9 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Peptidase_M17 PF00883.21 OAJ31499.1 - 2.6e-112 375.1 0.2 3.6e-112 374.7 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 OAJ31499.1 - 6.7e-08 32.4 0.1 1.6e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Pmp3 PF01679.17 OAJ31500.1 - 2.5e-20 72.4 8.5 2.5e-20 72.4 8.5 1.6 2 0 0 2 2 2 1 Proteolipid membrane potential modulator DUF3446 PF11928.8 OAJ31500.1 - 4.2 7.7 8.1 8.6 6.8 8.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain APS_kinase PF01583.20 OAJ31501.1 - 1.7e-70 236.0 0.0 2e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 OAJ31501.1 - 2.2e-06 27.9 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ31501.1 - 0.00045 20.8 0.0 0.00067 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 OAJ31501.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 OAJ31501.1 - 0.0073 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 OAJ31501.1 - 0.02 15.3 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF463 PF04317.12 OAJ31501.1 - 0.042 12.8 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Arf PF00025.21 OAJ31501.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 OAJ31501.1 - 0.098 11.9 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 OAJ31501.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family dNK PF01712.19 OAJ31501.1 - 0.14 12.0 0.0 6.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase WD40 PF00400.32 OAJ31502.1 - 3.1e-08 34.1 0.9 0.003 18.4 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_L1 PF00687.21 OAJ31503.1 - 9.9e-45 152.8 1.2 1.1e-44 152.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Adaptin_binding PF10199.9 OAJ31504.1 - 0.56 10.8 24.3 1.5 9.5 17.4 3.6 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 Fungal_trans PF04082.18 OAJ31505.1 - 2.1e-14 53.2 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ31505.1 - 2.4e-06 27.5 9.7 4.2e-06 26.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0020 PF01170.18 OAJ31506.1 - 1.9e-11 44.1 0.0 9.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 AviRa PF11599.8 OAJ31506.1 - 0.0032 17.0 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 OAJ31506.1 - 0.005 17.5 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ31506.1 - 0.011 16.4 0.0 0.052 14.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31506.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 OAJ31506.1 - 0.16 11.3 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family zf-CCCH_4 PF18044.1 OAJ31507.1 - 1.7e-06 27.7 3.6 3e-06 26.9 3.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ31507.1 - 1.9e-06 27.7 5.5 3.4e-06 26.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 OAJ31507.1 - 0.00058 19.7 2.2 0.001 19.0 2.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAJ31507.1 - 0.15 12.8 0.3 0.23 12.2 0.3 1.3 1 0 0 1 1 1 0 Torus domain NupH_GANP PF16768.5 OAJ31507.1 - 0.27 10.9 160.9 0.096 12.4 32.5 5.8 1 1 4 5 5 5 0 Nucleoporin homology of Germinal-centre associated nuclear protein zf-CCCH_2 PF14608.6 OAJ31507.1 - 0.28 11.7 3.5 0.53 10.8 3.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Nucleoporin_FG PF13634.6 OAJ31507.1 - 0.98 10.3 165.3 46 4.9 32.1 6.8 1 1 4 5 5 5 0 Nucleoporin FG repeat region RL10P_insert PF17777.1 OAJ31508.1 - 2.5e-23 81.8 0.2 9.8e-23 79.9 0.1 2.0 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 OAJ31508.1 - 3.8e-16 59.0 0.0 6.8e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 CENP-B_dimeris PF09026.10 OAJ31508.1 - 0.073 13.5 8.9 0.13 12.6 8.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 OAJ31508.1 - 0.28 11.6 4.8 0.63 10.5 4.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 OAJ31508.1 - 2.1 6.3 5.7 3.1 5.8 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ31508.1 - 2.1 7.6 5.9 3.2 7.0 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein JAB PF01398.21 OAJ31510.1 - 2.7e-28 98.3 0.2 4.3e-28 97.7 0.2 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 OAJ31510.1 - 5.9e-16 59.2 2.4 1e-13 52.0 2.4 2.7 1 1 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 OAJ31510.1 - 7.4e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Rrn6 PF10214.9 OAJ31510.1 - 0.048 12.2 1.3 0.067 11.7 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor UPF0172 PF03665.13 OAJ31510.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) EVC2_like PF12297.8 OAJ31510.1 - 0.28 9.8 0.4 0.4 9.3 0.4 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein TFIIF_alpha PF05793.12 OAJ31510.1 - 1.4 7.4 7.3 2 6.9 7.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CRIM PF16978.5 OAJ31511.1 - 4.5e-30 104.6 0.0 6.7e-27 94.4 0.0 2.8 3 0 0 3 3 3 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 OAJ31511.1 - 6.2e-22 78.0 0.0 9.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology MttA_Hcf106 PF02416.16 OAJ31512.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family Abhydrolase_6 PF12697.7 OAJ31513.1 - 4.7e-22 79.7 0.7 7.7e-22 79.0 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ31513.1 - 1.4e-09 37.6 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 OAJ31513.1 - 3.6e-07 30.1 0.1 2.7e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ31513.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAJ31513.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein His_biosynth PF00977.21 OAJ31514.1 - 6.5e-40 137.0 0.0 2.2e-24 86.2 0.0 3.0 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 OAJ31514.1 - 9.4e-17 61.4 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 OAJ31514.1 - 1.9e-07 30.9 0.0 4.2e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 OAJ31514.1 - 1.1e-06 28.6 0.0 5.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 OAJ31514.1 - 0.091 12.5 0.4 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Serglycin PF04360.12 OAJ31515.1 - 3.6 7.5 9.8 9.2 6.2 9.8 1.7 1 0 0 1 1 1 0 Serglycin SPX PF03105.19 OAJ31515.1 - 4.7 7.0 9.4 5.5 6.8 9.4 1.1 1 0 0 1 1 1 0 SPX domain Asp PF00026.23 OAJ31516.1 - 6.2e-61 206.5 0.7 7.7e-61 206.2 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ31516.1 - 1.2e-12 48.4 4.2 1.4e-11 44.9 4.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.16 OAJ31517.1 - 2.8e-18 66.0 10.9 2.8e-18 66.0 10.9 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 OAJ31518.1 - 2.6e-71 240.5 0.0 3.6e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 OAJ31518.1 - 6.4e-65 218.9 0.0 9.5e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 OAJ31518.1 - 2.6e-12 46.2 0.0 3.9e-05 22.5 0.0 3.2 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.25 OAJ31518.1 - 2.4e-11 43.8 0.0 6.3e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 OAJ31518.1 - 7.2e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 OAJ31518.1 - 0.00014 22.8 0.0 0.00095 20.1 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 OAJ31518.1 - 0.00097 18.2 0.0 0.03 13.3 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 OAJ31518.1 - 0.013 14.6 0.0 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CENP-B_dimeris PF09026.10 OAJ31518.1 - 0.15 12.5 0.6 0.34 11.3 0.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PTPlike_phytase PF14566.6 OAJ31519.1 - 3.5e-05 24.0 0.0 8.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 OAJ31519.1 - 0.0003 20.6 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAJ31519.1 - 0.0025 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2950 PF11453.8 OAJ31519.1 - 0.022 14.0 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Y_phosphatase PF00102.27 OAJ31519.1 - 0.041 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase EF-hand_7 PF13499.6 OAJ31520.1 - 1.1e-28 99.4 10.8 8.5e-15 55.0 4.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 OAJ31520.1 - 7.4e-28 94.0 13.1 3.1e-08 32.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 OAJ31520.1 - 1.1e-22 78.0 8.9 4.7e-07 29.2 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ31520.1 - 6.4e-19 67.5 11.3 2.3e-08 33.8 1.9 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAJ31520.1 - 6.8e-15 53.8 10.2 5.6e-05 22.4 1.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 OAJ31520.1 - 2.1e-12 47.2 0.5 1.5e-05 25.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ31520.1 - 2.6e-06 27.3 2.0 0.044 13.7 0.7 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 OAJ31520.1 - 0.00015 21.7 0.5 0.15 12.0 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 OAJ31520.1 - 0.0056 17.0 1.3 1.7 9.0 0.3 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 OAJ31520.1 - 0.046 14.1 1.6 0.76 10.2 0.5 2.3 2 1 0 2 2 2 0 EF-hand domain PhetRS_B1 PF18262.1 OAJ31520.1 - 0.11 12.8 3.0 0.14 12.4 1.4 1.9 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Dockerin_1 PF00404.18 OAJ31520.1 - 0.13 12.4 1.6 5.4 7.3 0.6 2.5 2 0 0 2 2 2 0 Dockerin type I domain SHOCT PF09851.9 OAJ31520.1 - 9.4 6.1 7.2 0.7 9.7 0.5 2.8 3 0 0 3 3 3 0 Short C-terminal domain UQ_con PF00179.26 OAJ31521.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Kei1 PF08552.11 OAJ31522.1 - 1.2e-50 172.0 1.4 1.5e-50 171.7 1.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 ICE2 PF08426.10 OAJ31523.1 - 1.6e-51 175.7 0.0 1.5e-48 165.9 0.0 3.1 1 1 0 1 1 1 1 ICE2 ATP-synt_ab PF00006.25 OAJ31524.1 - 1.1e-71 240.9 0.0 2e-71 240.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 OAJ31524.1 - 5e-43 146.4 0.5 8.2e-43 145.7 0.5 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 OAJ31524.1 - 1e-17 64.4 1.7 2.5e-17 63.1 1.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TniB PF05621.11 OAJ31524.1 - 0.037 13.4 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Sec62 PF03839.16 OAJ31525.1 - 3.8e-50 170.4 1.8 6.7e-50 169.6 1.8 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 DUF2207 PF09972.9 OAJ31525.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_pol_I_TF PF04090.12 OAJ31526.1 - 9e-06 25.3 0.0 8.2e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor DUF92 PF01940.16 OAJ31527.1 - 6.4e-43 146.9 2.4 7.8e-43 146.6 2.4 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Methyltr_RsmB-F PF01189.17 OAJ31529.1 - 7.5e-30 104.1 0.0 1e-19 71.0 0.0 3.6 3 1 0 3 3 3 3 16S rRNA methyltransferase RsmB/F SDA1 PF05285.12 OAJ31530.1 - 0.00012 21.7 11.0 0.00021 20.8 11.0 1.4 1 0 0 1 1 1 1 SDA1 CobT PF06213.12 OAJ31530.1 - 8.6 5.7 19.0 17 4.7 19.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Carb_kinase PF01256.17 OAJ31531.1 - 7.5e-55 186.1 0.0 9.6e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 OAJ31531.1 - 0.00039 19.9 0.0 0.0022 17.4 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase DUF4516 PF14990.6 OAJ31531.1 - 0.027 14.2 1.2 0.14 11.9 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4516) FluMu_N PF17891.1 OAJ31531.1 - 3.4 7.5 4.5 11 5.8 0.1 3.0 2 1 1 3 3 3 0 Mu-like prophage FluMu N-terminal domain COG6 PF06419.11 OAJ31532.1 - 1.9e-122 409.6 0.0 4.2e-63 213.6 0.0 2.2 2 0 0 2 2 2 2 Conserved oligomeric complex COG6 p450 PF00067.22 OAJ31533.1 - 2.8e-40 138.4 0.0 5.9e-40 137.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 TF_AP-2 PF03299.14 OAJ31533.1 - 0.11 12.5 1.0 0.69 9.8 0.2 2.4 2 1 0 3 3 3 0 Transcription factor AP-2 GMC_oxred_N PF00732.19 OAJ31534.1 - 6.1e-13 48.8 0.0 7e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 OAJ31534.1 - 9.4e-05 22.6 0.1 0.00028 21.1 0.1 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 OAJ31534.1 - 0.0024 18.0 0.0 0.0029 17.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 OAJ31534.1 - 0.0032 16.7 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ31534.1 - 0.0054 16.0 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 OAJ31534.1 - 0.013 16.1 0.0 0.017 15.7 0.0 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 OAJ31534.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 OAJ31534.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 OAJ31534.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 OAJ31534.1 - 0.024 13.7 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 OAJ31534.1 - 0.025 14.8 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 OAJ31534.1 - 0.043 12.5 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 OAJ31534.1 - 0.089 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ31534.1 - 0.18 10.9 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.13 OAJ31535.1 - 1.9e-28 99.8 0.2 2.8e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 OAJ31535.1 - 4.9e-20 72.1 0.0 7.4e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase SLC12 PF03522.15 OAJ31536.1 - 0.00062 18.9 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 OAJ31538.1 - 8e-23 81.5 1.1 8e-23 81.5 1.1 5.3 5 1 0 5 5 5 1 RNA polymerase III RPC4 Leo1 PF04004.13 OAJ31538.1 - 0.057 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Leo1-like protein ABC_tran PF00005.27 OAJ31539.1 - 7.4e-33 114.0 0.0 1.5e-32 112.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 OAJ31539.1 - 3.8e-32 112.0 4.4 9.5e-32 110.7 4.4 1.7 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 OAJ31539.1 - 0.0011 19.3 0.2 0.0043 17.4 0.2 2.1 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 OAJ31539.1 - 0.0013 18.3 0.0 0.033 13.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ31539.1 - 0.0035 17.3 0.0 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 OAJ31539.1 - 0.0036 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 OAJ31539.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 OAJ31539.1 - 0.037 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Acyl_transf_3 PF01757.22 OAJ31540.1 - 6.1e-17 61.7 42.9 1.5e-16 60.4 42.9 1.7 1 1 0 1 1 1 1 Acyltransferase family Presenilin PF01080.17 OAJ31540.1 - 0.057 12.2 1.8 0.11 11.2 1.8 1.4 1 0 0 1 1 1 0 Presenilin Metal_resist PF13801.6 OAJ31541.1 - 0.0086 16.3 1.8 0.0086 16.3 1.8 2.4 2 0 0 2 2 2 1 Heavy-metal resistance Med9 PF07544.13 OAJ31541.1 - 0.05 13.7 0.1 0.05 13.7 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 OEP PF02321.18 OAJ31541.1 - 0.061 13.1 0.3 0.061 13.1 0.3 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein PRP38 PF03371.15 OAJ31542.1 - 3e-59 199.8 0.3 3.7e-59 199.5 0.3 1.1 1 0 0 1 1 1 1 PRP38 family Adeno_VII PF03228.14 OAJ31542.1 - 0.058 14.0 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 Adenoviral core protein VII Cwf_Cwc_15 PF04889.12 OAJ31542.1 - 0.98 9.1 16.1 0.041 13.6 7.4 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FMO-like PF00743.19 OAJ31543.1 - 4.6e-18 64.9 0.0 2.2e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 OAJ31543.1 - 4.8e-08 32.6 0.0 0.00087 18.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ31543.1 - 2.5e-07 30.3 0.0 8.7e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ31543.1 - 5.3e-06 26.5 0.2 0.0002 21.4 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 OAJ31543.1 - 0.0007 19.3 0.1 0.0051 16.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 OAJ31543.1 - 0.0021 17.3 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 OAJ31543.1 - 0.0025 18.0 0.0 0.0064 16.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Y_phosphatase PF00102.27 OAJ31544.1 - 4.4e-52 177.0 0.2 1.2e-44 152.7 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 OAJ31544.1 - 0.0023 18.4 0.0 0.037 14.5 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 OAJ31544.1 - 0.016 15.0 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 OAJ31544.1 - 0.031 14.2 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Dicty_REP PF05086.12 OAJ31544.1 - 0.3 9.0 2.2 0.58 8.1 2.2 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp PF00026.23 OAJ31545.1 - 1.7e-49 169.0 0.1 8.4e-49 166.7 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ31545.1 - 1.5e-06 28.5 0.4 0.031 14.5 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ31545.1 - 4.4e-06 27.3 0.8 0.022 15.4 0.1 2.5 2 0 0 2 2 2 2 Aspartyl protease Arv1 PF04161.13 OAJ31546.1 - 5.7e-25 88.7 0.4 2.3e-19 70.4 0.0 2.3 2 0 0 2 2 2 2 Arv1-like family ABM PF03992.16 OAJ31547.1 - 2.9e-08 33.7 0.1 3.6e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase TMA7 PF09072.10 OAJ31548.1 - 0.096 13.5 0.1 0.13 13.1 0.1 1.2 1 0 0 1 1 1 0 Translation machinery associated TMA7 HpcH_HpaI PF03328.14 OAJ31549.1 - 7.9e-38 129.8 0.1 3.8e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 OAJ31549.1 - 2e-08 33.8 0.0 0.00084 18.6 0.0 2.5 2 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Anoctamin PF04547.12 OAJ31550.1 - 2.5e-97 326.6 0.2 3.1e-97 326.3 0.2 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel LapA_dom PF06305.11 OAJ31550.1 - 2.4 8.0 6.2 0.69 9.8 1.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain BAG PF02179.16 OAJ31551.1 - 2.4e-14 53.5 0.0 6.9e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 BAG domain ubiquitin PF00240.23 OAJ31551.1 - 9.4e-09 34.9 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TarH PF02203.15 OAJ31551.1 - 0.0068 16.4 5.8 0.011 15.7 5.8 1.3 1 0 0 1 1 1 1 Tar ligand binding domain homologue Ubiquitin_2 PF14560.6 OAJ31551.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Thioredoxin_8 PF13905.6 OAJ31552.1 - 7.1e-10 39.1 0.0 2.4e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 OAJ31552.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 OAJ31552.1 - 0.0063 16.4 0.0 0.029 14.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family GATase_2 PF00310.21 OAJ31553.1 - 6.4e-179 595.1 0.0 8.6e-179 594.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 OAJ31553.1 - 2.6e-156 520.4 0.1 7.4e-156 518.9 0.0 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 OAJ31553.1 - 3.6e-111 371.1 0.0 9.6e-111 369.7 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 OAJ31553.1 - 3.5e-87 290.9 2.6 6.2e-87 290.1 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 OAJ31553.1 - 9.5e-28 97.3 0.1 8.7e-27 94.1 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 OAJ31553.1 - 6.7e-22 77.4 0.1 1.8e-21 76.0 0.1 1.8 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 OAJ31553.1 - 4.4e-09 36.4 0.0 1.5e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 OAJ31553.1 - 1.9e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 OAJ31553.1 - 3.9e-07 30.5 3.2 0.00014 22.3 0.3 3.9 3 1 1 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ31553.1 - 1.7e-05 24.4 0.3 1.7e-05 24.4 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 OAJ31553.1 - 5.5e-05 22.6 0.2 0.035 13.4 0.0 3.9 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ31553.1 - 9.8e-05 21.2 0.2 9.8e-05 21.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 OAJ31553.1 - 0.00012 21.3 0.8 0.00063 18.9 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 OAJ31553.1 - 0.00016 21.4 1.5 0.0011 18.6 0.5 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 OAJ31553.1 - 0.00019 20.8 0.1 0.51 9.6 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ31553.1 - 0.00039 19.8 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 OAJ31553.1 - 0.00091 18.5 0.1 0.00091 18.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 OAJ31553.1 - 0.0025 17.0 0.1 0.67 8.9 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein FMN_dh PF01070.18 OAJ31553.1 - 0.0054 15.8 3.4 0.021 13.9 1.8 2.6 3 0 0 3 3 3 1 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ31553.1 - 0.0096 15.3 0.1 0.048 13.0 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 OAJ31553.1 - 0.0097 15.0 0.6 0.061 12.4 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 OAJ31553.1 - 0.012 16.1 0.7 1.1 9.7 0.1 3.1 2 0 0 2 2 2 0 Putative NAD(P)-binding GATase_6 PF13522.6 OAJ31553.1 - 0.094 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_Gly3P_dh_N PF01210.23 OAJ31553.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.21 OAJ31553.1 - 0.3 11.1 3.9 15 5.6 0.0 3.5 4 0 0 4 4 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 OAJ31553.1 - 0.4 10.5 1.7 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Rossmann-like domain DJ-1_PfpI PF01965.24 OAJ31553.1 - 0.48 10.2 1.7 38 4.0 0.1 3.0 1 1 1 3 3 3 0 DJ-1/PfpI family SAC3_GANP PF03399.16 OAJ31555.1 - 7e-25 88.0 5.2 7.2e-23 81.4 5.2 2.3 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 OAJ31555.1 - 0.001 19.0 0.2 0.0029 17.6 0.2 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family YEATS PF03366.16 OAJ31556.1 - 5.3e-38 128.9 0.0 8.7e-38 128.2 0.0 1.4 1 0 0 1 1 1 1 YEATS family DUF2570 PF10828.8 OAJ31556.1 - 1.5 8.6 4.1 1.3 8.9 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) GST_C_6 PF17171.4 OAJ31557.1 - 0.0019 18.0 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain p47_phox_C PF08944.11 OAJ31557.1 - 0.49 9.8 7.7 0.19 11.1 1.0 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain Actin PF00022.19 OAJ31558.1 - 3.4e-19 68.7 0.0 2.1e-10 39.8 0.0 3.3 3 1 0 3 3 3 3 Actin Actin_micro PF17003.5 OAJ31558.1 - 5.4e-11 42.3 0.0 9.2e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family DUF3188 PF11384.8 OAJ31559.1 - 0.014 15.1 1.4 0.03 14.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) PspB PF06667.12 OAJ31559.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 Phage shock protein B Kinesin PF00225.23 OAJ31561.1 - 4.4e-92 308.5 0.0 4.4e-92 308.5 0.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ31561.1 - 2.8e-49 166.9 0.0 6.1e-49 165.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Macoilin PF09726.9 OAJ31561.1 - 5.5e-05 21.9 10.3 5.5e-05 21.9 10.3 2.2 2 0 0 2 2 2 1 Macoilin family CENP-K PF11802.8 OAJ31561.1 - 0.028 14.0 13.4 0.059 12.9 13.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K Surfac_D-trimer PF09006.11 OAJ31561.1 - 0.044 13.7 4.0 0.071 13.0 2.6 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.6 OAJ31561.1 - 3.1 6.3 15.4 6.2 5.3 15.4 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M43 PF05572.13 OAJ31562.1 - 2.5e-16 59.9 0.4 5.1e-16 58.9 0.4 1.6 1 1 1 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_4 PF13583.6 OAJ31562.1 - 0.00042 20.0 0.0 0.00095 18.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 OAJ31562.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 OAJ31562.1 - 0.005 17.4 0.3 0.066 13.7 0.3 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 OAJ31562.1 - 0.0064 16.7 0.1 0.012 15.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 OAJ31562.1 - 0.034 14.3 0.1 0.069 13.3 0.1 1.7 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Vps36_ESCRT-II PF11605.8 OAJ31563.1 - 1.3e-20 73.3 0.0 2.6e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 OAJ31563.1 - 5.1e-19 68.5 0.1 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 EAP30/Vps36 family Rubredoxin PF00301.20 OAJ31563.1 - 0.053 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin Vps36-NZF-N PF16988.5 OAJ31563.1 - 0.092 12.2 3.3 0.31 10.5 3.3 1.9 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 OAJ31563.1 - 0.27 10.6 1.7 0.51 9.7 1.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CTU2 PF10288.9 OAJ31563.1 - 0.81 10.0 5.9 0.33 11.2 2.2 2.2 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 CENP-B_dimeris PF09026.10 OAJ31563.1 - 0.98 9.9 4.9 2.4 8.6 4.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HsbA PF12296.8 OAJ31564.1 - 2.4e-06 28.0 3.7 2.4e-06 28.0 3.7 2.2 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Vps51 PF08700.11 OAJ31564.1 - 0.054 13.6 0.6 1.7 8.8 0.0 2.8 1 1 2 3 3 3 0 Vps51/Vps67 DEC-1_N PF04625.13 OAJ31564.1 - 0.29 10.1 8.8 0.43 9.6 8.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5525 PF17663.1 OAJ31564.1 - 1.8 6.5 14.0 2.2 6.2 14.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Frag1 PF10277.9 OAJ31565.1 - 3.2e-38 131.5 14.9 3.7e-38 131.3 14.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Yip1 PF04893.17 OAJ31565.1 - 0.0063 16.2 4.5 0.0063 16.2 4.5 2.5 1 1 1 2 2 2 1 Yip1 domain DASH_Dad1 PF08649.10 OAJ31566.1 - 2e-22 79.1 0.8 2.5e-22 78.8 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF5320 PF17253.2 OAJ31566.1 - 5.1 8.2 9.5 15 6.7 8.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) PilJ PF13675.6 OAJ31569.1 - 0.025 14.6 0.7 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Prefoldin PF02996.17 OAJ31569.1 - 0.029 14.3 2.8 0.044 13.7 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.15 OAJ31569.1 - 0.031 14.1 3.9 0.032 14.0 1.7 2.0 2 0 0 2 2 2 0 Septum formation initiator BRE1 PF08647.11 OAJ31569.1 - 0.077 13.1 1.7 0.29 11.2 1.7 2.0 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 OAJ31569.1 - 0.35 10.2 6.5 6.2 6.1 3.8 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) FlgN PF05130.12 OAJ31569.1 - 0.56 10.7 7.2 0.26 11.8 3.8 2.1 2 0 0 2 2 2 0 FlgN protein DUF4140 PF13600.6 OAJ31569.1 - 6.6 7.2 7.3 3.8 8.0 0.7 3.4 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) CCAP PF11105.8 OAJ31571.1 - 0.087 12.8 3.3 1.3 9.0 0.6 2.1 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Fer2_2 PF01799.20 OAJ31571.1 - 5.5 7.1 9.0 0.52 10.4 1.6 2.6 2 1 0 2 2 2 0 [2Fe-2S] binding domain PINIT PF14324.6 OAJ31573.1 - 3.6e-23 82.5 0.3 5.2e-23 82.0 0.3 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 OAJ31573.1 - 2.3e-21 75.3 4.0 3.6e-21 74.6 4.0 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 OAJ31573.1 - 1.9e-08 34.0 0.9 3.6e-08 33.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 OAJ31573.1 - 0.05 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf-C3HC4_2 PF13923.6 OAJ31573.1 - 0.8 9.6 3.3 1.5 8.8 3.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3915 PF13054.6 OAJ31573.1 - 8.1 6.5 5.3 24 4.9 5.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) CS PF04969.16 OAJ31574.1 - 7.4e-19 68.6 0.1 1.3e-18 67.7 0.1 1.4 1 0 0 1 1 1 1 CS domain CLU PF13236.6 OAJ31575.1 - 7.5e-69 231.9 0.0 1.3e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 OAJ31575.1 - 5.7e-46 156.7 0.0 1.4e-45 155.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 OAJ31575.1 - 4.2e-21 75.0 14.7 7.5e-10 39.0 1.3 4.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ31575.1 - 7e-07 28.9 19.5 0.0052 16.6 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat CLU_N PF15044.6 OAJ31575.1 - 7e-06 26.3 0.1 5.4e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 OAJ31575.1 - 0.00018 21.1 0.2 0.0063 16.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ31575.1 - 0.073 13.9 5.3 0.33 11.9 0.0 4.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ31575.1 - 0.081 13.0 1.4 2.9 8.1 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ31575.1 - 5.7 7.3 10.8 0.96 9.7 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 OAJ31576.1 - 0.0058 16.4 2.7 0.012 15.4 0.8 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Ribosomal_L4 PF00573.22 OAJ31577.1 - 7e-40 136.8 0.3 7e-40 136.8 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 OAJ31577.1 - 1.2e-27 95.8 0.2 1.2e-27 95.8 0.2 2.4 4 0 0 4 4 4 1 60S ribosomal protein L4 C-terminal domain U79_P34 PF03064.16 OAJ31577.1 - 0.1 11.9 0.2 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PHD PF00628.29 OAJ31579.1 - 4e-10 39.4 8.1 7.5e-10 38.6 8.1 1.5 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 OAJ31579.1 - 1.7e-05 24.8 3.2 8.8e-05 22.4 0.1 2.3 2 0 0 2 2 2 1 CpG binding protein zinc finger C terminal domain PHD_2 PF13831.6 OAJ31579.1 - 0.21 11.2 2.5 0.39 10.3 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 OAJ31580.1 - 7.2e-31 106.6 6.5 7.2e-31 106.6 6.5 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 OAJ31580.1 - 2.2e-23 83.4 0.3 2.2e-23 83.4 0.3 3.9 3 0 0 3 3 3 2 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 OAJ31580.1 - 1.5e-22 79.6 5.7 1.5e-22 79.6 5.7 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 OAJ31580.1 - 7.6e-20 70.8 0.1 1.5e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 OAJ31580.1 - 4.3e-13 48.6 1.9 4.3e-13 48.6 1.9 2.6 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 OAJ31580.1 - 1.3e-10 41.6 0.9 3.4e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 PWWP domain PHD PF00628.29 OAJ31580.1 - 1.8e-09 37.3 8.8 1.8e-09 37.3 8.8 2.7 2 0 0 2 2 2 1 PHD-finger AAA PF00004.29 OAJ31581.1 - 3.3e-47 160.2 0.0 2.3e-41 141.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 OAJ31581.1 - 4.1e-09 36.1 0.0 1.1e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 OAJ31581.1 - 2.7e-07 31.1 0.2 4.1e-05 24.0 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 OAJ31581.1 - 1.4e-05 25.2 0.0 4.9e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 OAJ31581.1 - 7.3e-05 22.6 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 OAJ31581.1 - 9.7e-05 22.5 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ31581.1 - 0.0021 18.0 0.0 0.0084 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 OAJ31581.1 - 0.0046 16.7 0.0 0.91 9.2 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 OAJ31581.1 - 0.007 16.6 0.9 0.099 12.9 0.2 3.2 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 OAJ31581.1 - 0.017 15.2 0.6 0.052 13.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 OAJ31581.1 - 0.022 15.3 0.0 0.068 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ31581.1 - 0.022 15.2 0.1 0.15 12.6 0.0 2.4 3 0 0 3 3 2 0 ABC transporter ResIII PF04851.15 OAJ31581.1 - 0.028 14.4 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 OAJ31581.1 - 0.03 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 OAJ31581.1 - 0.046 13.8 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Bromodomain AAA_7 PF12775.7 OAJ31581.1 - 0.05 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 OAJ31581.1 - 0.06 12.9 2.2 0.15 11.6 0.0 2.7 4 0 0 4 4 2 0 AAA domain RNA_helicase PF00910.22 OAJ31581.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 OAJ31581.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 OAJ31581.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 OAJ31581.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 OAJ31581.1 - 0.12 12.4 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_14 PF13173.6 OAJ31581.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 OAJ31581.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 OAJ31583.1 - 2.8e-31 108.7 28.8 2.8e-31 108.7 28.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily COX6C PF02937.15 OAJ31583.1 - 0.1 12.7 1.3 2.1 8.5 0.0 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIc Vpu PF00558.19 OAJ31583.1 - 0.3 10.9 1.4 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Vpu protein Prominin PF05478.11 OAJ31583.1 - 8.8 4.1 7.7 9.3 4.1 6.6 1.5 2 0 0 2 2 2 0 Prominin Helicase_C PF00271.31 OAJ31584.1 - 1.5e-18 67.1 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Menin PF05053.13 OAJ31584.1 - 0.57 8.5 3.0 0.8 8.0 3.0 1.2 1 0 0 1 1 1 0 Menin PBP1_TM PF14812.6 OAJ31584.1 - 0.6 10.5 7.2 3.1 8.2 7.2 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 OAJ31584.1 - 1.4 8.1 5.4 2.3 7.4 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 OAJ31584.1 - 2.5 6.3 6.7 3.8 5.7 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 OAJ31584.1 - 3.6 7.3 4.6 8.1 6.1 4.6 1.6 1 0 0 1 1 1 0 FAM176 family 4HBT PF03061.22 OAJ31585.1 - 4.5e-11 43.0 0.0 8.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 OAJ31585.1 - 0.0041 17.4 0.0 0.008 16.5 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3659 PF12396.8 OAJ31585.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) DnaJ_C PF01556.18 OAJ31586.1 - 1.8e-29 102.7 0.0 2.8e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 OAJ31586.1 - 3.7e-26 91.0 1.4 5.8e-26 90.4 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 OAJ31586.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein AAA_12 PF13087.6 OAJ31587.1 - 4.2e-45 153.8 0.0 6.3e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ31587.1 - 9.3e-39 133.8 0.0 2.9e-38 132.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 OAJ31587.1 - 4.6e-14 53.0 0.0 2.3e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ31587.1 - 3.4e-10 40.0 0.5 5.2e-08 32.8 0.5 2.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 OAJ31587.1 - 0.00012 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 OAJ31587.1 - 0.00032 20.5 0.1 4.8 6.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 OAJ31587.1 - 0.054 13.9 1.2 0.17 12.2 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 OAJ31587.1 - 0.064 13.3 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 OAJ31587.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.14 OAJ31587.1 - 0.13 12.3 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) OTU PF02338.19 OAJ31589.1 - 5.9e-13 49.4 0.0 9.8e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 OAJ31589.1 - 0.0072 15.8 0.0 3.7 6.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain VHS PF00790.19 OAJ31591.1 - 1.5e-19 70.2 0.2 2.6e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 VHS domain Serglycin PF04360.12 OAJ31591.1 - 4.8 7.1 9.7 0.39 10.7 3.9 2.1 2 0 0 2 2 2 0 Serglycin Vps35 PF03635.17 OAJ31592.1 - 0 1023.9 0.0 0 1023.3 0.0 1.3 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RRM_1 PF00076.22 OAJ31593.1 - 1.6e-21 75.9 0.0 2.3e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ31593.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ31593.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Adaptin_N PF01602.20 OAJ31594.1 - 1.2e-136 456.4 7.4 1.5e-136 456.0 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 OAJ31594.1 - 7.9e-63 211.3 3.8 1.2e-59 200.9 0.5 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 OAJ31594.1 - 6.9e-19 68.0 2.4 2.6e-06 27.7 0.0 6.2 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 OAJ31594.1 - 1.3e-12 46.8 4.0 0.0012 18.9 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 OAJ31594.1 - 1.5e-07 31.7 1.0 0.33 11.5 0.0 6.7 8 0 0 8 8 8 1 HEAT-like repeat Cnd3 PF12719.7 OAJ31594.1 - 1.2e-05 24.7 0.5 0.0039 16.4 0.0 3.0 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 OAJ31594.1 - 0.00016 21.8 2.0 0.76 10.0 0.0 4.5 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 OAJ31594.1 - 0.0013 18.3 0.2 1.8 8.1 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal Sec7_N PF12783.7 OAJ31594.1 - 0.067 13.1 1.3 0.21 11.5 0.4 2.2 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Aminoglyc_resit PF10706.9 OAJ31594.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-C2H2 PF00096.26 OAJ31595.1 - 1.4e-05 25.2 12.4 0.07 13.6 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ31595.1 - 3.5e-05 24.0 2.2 3.5e-05 24.0 2.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ31595.1 - 0.00045 20.8 10.8 0.065 14.1 7.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 OAJ31595.1 - 0.017 15.6 1.3 0.036 14.5 1.3 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 OAJ31595.1 - 0.042 14.2 7.3 0.089 13.1 2.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAJ31595.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain RINGv PF12906.7 OAJ31596.1 - 7.2e-06 26.0 8.1 2e-05 24.6 2.9 2.4 2 0 0 2 2 2 1 RING-variant domain Zn_ribbon_17 PF17120.5 OAJ31596.1 - 0.091 12.4 1.5 0.25 11.0 1.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 OAJ31596.1 - 0.7 10.3 9.2 0.099 13.0 4.4 1.9 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 OAJ31596.1 - 1.4 9.2 4.7 0.51 10.6 1.6 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain UCH PF00443.29 OAJ31597.1 - 3.5e-47 161.0 0.0 4.3e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ31597.1 - 6.6e-11 42.4 4.6 2.9e-09 37.0 4.6 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 OAJ31597.1 - 3.7e-09 36.2 0.0 7.6e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 OAJ31597.1 - 0.023 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ31597.1 - 0.17 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain AP3D1 PF06375.11 OAJ31597.1 - 0.36 11.0 4.0 0.71 10.1 4.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TIMELESS PF04821.14 OAJ31599.1 - 6.3e-72 242.2 0.0 6.3e-72 242.2 0.0 2.1 2 0 0 2 2 2 1 Timeless protein RasGEF PF00617.19 OAJ31600.1 - 2.8e-40 138.4 0.0 6.7e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 OAJ31600.1 - 1.4e-17 63.8 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_2 PF07653.17 OAJ31600.1 - 4e-14 52.0 0.1 8.9e-14 50.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 OAJ31600.1 - 1.6e-13 50.3 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 OAJ31600.1 - 7.8e-13 47.8 0.0 1.4e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain RhoGAP PF00620.27 OAJ31600.1 - 0.18 11.6 0.0 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain Pkinase PF00069.25 OAJ31601.1 - 4e-20 72.3 0.0 1.1e-19 70.8 0.0 1.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31601.1 - 8.6e-06 25.2 0.0 2.9e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 OAJ31601.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 OAJ31601.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ31601.1 - 0.097 12.6 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NDUF_B12 PF08122.12 OAJ31602.1 - 1.1 9.4 3.2 0.97 9.5 0.2 2.2 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family KH_1 PF00013.29 OAJ31605.1 - 3.3e-42 142.2 10.4 1.7e-16 59.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 OAJ31605.1 - 2.2e-09 37.0 9.1 0.0062 16.3 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 OAJ31605.1 - 2.3e-07 30.6 1.8 0.062 13.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 OAJ31605.1 - 0.0052 16.8 6.4 0.37 10.9 0.3 3.3 3 0 0 3 3 3 1 NusA-like KH domain Complex1_LYR PF05347.15 OAJ31606.1 - 5e-05 23.3 0.1 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 OAJ31606.1 - 0.0085 16.8 1.5 0.014 16.1 1.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Ldh_1_N PF00056.23 OAJ31607.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABC_tran PF00005.27 OAJ31608.1 - 1.4e-47 161.7 0.0 2.7e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 OAJ31608.1 - 1.1e-38 133.5 15.4 2.7e-21 76.5 3.8 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 OAJ31608.1 - 1.5e-11 44.2 0.2 3.1e-05 23.5 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 OAJ31608.1 - 2.4e-05 24.3 0.1 0.05 13.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 OAJ31608.1 - 4e-05 23.7 2.2 0.054 13.6 0.2 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 OAJ31608.1 - 0.00011 21.8 0.9 0.48 10.2 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ31608.1 - 0.00016 22.0 1.2 0.59 10.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 OAJ31608.1 - 0.00025 21.2 0.6 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain MMR_HSR1 PF01926.23 OAJ31608.1 - 0.00037 20.6 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ31608.1 - 0.00049 19.7 0.0 0.55 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 OAJ31608.1 - 0.00072 20.1 0.1 0.14 12.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 OAJ31608.1 - 0.0013 18.2 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_15 PF13175.6 OAJ31608.1 - 0.0037 17.0 0.1 0.96 9.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 OAJ31608.1 - 0.0047 17.3 0.3 3.4 8.0 0.1 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAJ31608.1 - 0.005 16.7 2.6 7.8 6.2 0.0 3.9 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 OAJ31608.1 - 0.0082 15.9 0.1 0.91 9.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein T2SSE PF00437.20 OAJ31608.1 - 0.015 14.3 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 OAJ31608.1 - 0.016 14.5 0.2 3.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 OAJ31608.1 - 0.039 14.2 0.1 5.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 OAJ31608.1 - 0.049 14.2 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 OAJ31608.1 - 0.05 12.8 0.2 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 OAJ31608.1 - 0.074 12.8 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 OAJ31608.1 - 0.24 11.5 2.1 20 5.3 0.2 2.8 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 OAJ31608.1 - 1.3 9.3 3.3 1.5 9.1 0.0 2.7 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF1097 PF06496.11 OAJ31608.1 - 8 6.6 14.2 0.23 11.6 3.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) KDZ PF18758.1 OAJ31609.1 - 1.7e-06 27.8 0.2 2.3e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Striatin PF08232.12 OAJ31610.1 - 0.0037 17.9 1.0 0.0037 17.9 1.0 2.7 3 0 0 3 3 3 1 Striatin family AICARFT_IMPCHas PF01808.18 OAJ31611.1 - 0.069 12.6 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Aminotran_1_2 PF00155.21 OAJ31612.1 - 1.4e-54 185.6 0.0 2.6e-54 184.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 OAJ31612.1 - 0.021 14.1 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase adh_short PF00106.25 OAJ31613.1 - 5.2e-26 91.3 0.0 2e-24 86.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ31613.1 - 6.4e-14 52.1 0.1 1.5e-12 47.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ31613.1 - 3.7e-08 33.5 0.8 1.2e-07 31.8 0.8 1.8 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 OAJ31613.1 - 0.0016 17.8 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 OAJ31613.1 - 0.023 14.6 0.1 0.68 9.8 0.1 2.4 1 1 0 1 1 1 0 NAD(P)H-binding F420_oxidored PF03807.17 OAJ31613.1 - 0.035 14.7 0.2 0.075 13.6 0.2 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 OAJ31613.1 - 0.036 14.0 0.1 0.062 13.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 OAJ31613.1 - 0.084 12.8 0.1 0.25 11.2 0.2 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Mito_carr PF00153.27 OAJ31614.1 - 1e-70 233.7 5.3 4.1e-23 81.1 0.1 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ31614.1 - 0.016 14.4 0.3 0.18 10.9 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease GAD-like PF08887.11 OAJ31614.1 - 0.031 14.1 0.2 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 GAD-like domain Pkinase PF00069.25 OAJ31615.1 - 4.1e-66 223.0 0.0 6.7e-66 222.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31615.1 - 1.3e-37 129.5 0.0 6.6e-35 120.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ31615.1 - 0.0011 17.8 0.0 0.004 16.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 OAJ31615.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 OAJ31615.1 - 0.1 12.5 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 OAJ31615.1 - 0.11 12.1 0.1 0.38 10.3 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.11 OAJ31615.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_21 PF13304.6 OAJ31617.1 - 0.026 14.3 0.1 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1168 PF06658.12 OAJ31617.1 - 0.57 10.0 7.7 1.4 8.8 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.14 OAJ31617.1 - 2.6 7.8 8.4 3.8 7.3 4.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.10 OAJ31617.1 - 5 7.9 9.5 1.8 9.3 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PTP_tm PF18861.1 OAJ31618.1 - 0.044 13.8 0.7 0.072 13.1 0.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 OAJ31618.1 - 0.2 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless AAA PF00004.29 OAJ31619.1 - 1.7e-40 138.5 0.0 3.4e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 OAJ31619.1 - 1.1e-26 92.6 0.1 3.3e-26 91.1 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 OAJ31619.1 - 2.2e-22 78.9 8.9 5.4e-22 77.6 8.9 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 OAJ31619.1 - 1.4e-08 34.4 0.0 2.3e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 OAJ31619.1 - 4.3e-05 23.9 0.1 0.0075 16.7 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 OAJ31619.1 - 8.7e-05 21.9 0.3 0.00023 20.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 OAJ31619.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 OAJ31619.1 - 0.00027 20.9 0.0 0.00081 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 OAJ31619.1 - 0.00036 20.3 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 OAJ31619.1 - 0.00059 20.1 0.1 0.052 13.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ31619.1 - 0.0013 18.8 1.5 0.0015 18.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 OAJ31619.1 - 0.0016 18.8 0.0 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 OAJ31619.1 - 0.003 17.6 0.2 0.01 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 OAJ31619.1 - 0.005 17.0 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 OAJ31619.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 OAJ31619.1 - 0.014 16.0 0.1 0.1 13.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 OAJ31619.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 OAJ31619.1 - 0.017 15.6 0.1 0.052 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 OAJ31619.1 - 0.018 14.6 0.1 0.97 9.0 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 OAJ31619.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 OAJ31619.1 - 0.062 12.6 0.0 6.1 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 OAJ31619.1 - 0.12 12.1 0.0 0.61 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 OAJ31619.1 - 0.28 10.6 1.2 0.4 10.1 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein Pro_isomerase PF00160.21 OAJ31621.1 - 1.5e-52 178.1 0.0 1.7e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PEMT PF04191.13 OAJ31622.1 - 9.1e-22 77.5 0.9 9.1e-22 77.5 0.9 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase EBV-NA3 PF05009.12 OAJ31622.1 - 0.071 12.6 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) HEAT PF02985.22 OAJ31622.1 - 0.17 12.2 0.5 3.4 8.2 0.2 2.6 2 0 0 2 2 2 0 HEAT repeat ERG4_ERG24 PF01222.17 OAJ31623.1 - 9.4e-121 403.6 21.5 1.1e-120 403.3 21.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hydrolase_like PF13242.6 OAJ31625.1 - 6e-07 29.4 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 OAJ31625.1 - 5.5e-06 26.6 0.0 7.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 OAJ31625.1 - 0.12 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 OAJ31625.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 1 1 2 2 2 0 Mitochondrial PGP phosphatase WD40 PF00400.32 OAJ31626.1 - 0.0011 19.7 0.0 0.58 11.1 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Bac_chlorC PF02043.17 OAJ31626.1 - 0.077 13.0 0.7 4.8 7.3 0.2 2.9 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Sugar_tr PF00083.24 OAJ31627.1 - 8.6e-44 150.1 22.8 3e-42 145.1 22.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ31627.1 - 5.9e-16 58.3 36.0 7e-08 31.8 17.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ31627.1 - 0.00024 19.6 1.8 0.011 14.0 0.0 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M16 PF00675.20 OAJ31628.1 - 1.9e-15 57.1 0.0 4.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 OAJ31628.1 - 2.5e-06 27.6 0.0 5.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Robl_LC7 PF03259.17 OAJ31628.1 - 3.2 7.6 5.1 0.9 9.4 0.2 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain PhoLip_ATPase_C PF16212.5 OAJ31629.1 - 6.1e-71 239.1 25.4 6.1e-71 239.1 25.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ31629.1 - 4.9e-20 71.0 3.3 4.9e-20 71.0 3.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 OAJ31629.1 - 1.4e-12 47.5 0.0 6.9e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 OAJ31629.1 - 1.1e-09 38.9 1.8 6.1e-05 23.4 0.8 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ31629.1 - 1.1e-06 28.4 0.7 5.2e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 OAJ31629.1 - 0.00093 19.0 0.7 0.0087 15.8 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_1 PF00515.28 OAJ31630.1 - 9.8e-24 82.2 1.9 5.5e-09 35.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ31630.1 - 2.4e-18 65.6 5.5 1.9e-07 30.6 1.3 3.5 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 OAJ31630.1 - 9e-17 59.8 9.6 1.6e-07 30.9 0.2 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ31630.1 - 1.4e-12 47.0 0.8 2e-06 27.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ31630.1 - 6.2e-12 44.7 1.8 7.8e-06 25.7 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ31630.1 - 1.2e-08 35.0 14.3 1.3e-05 25.6 0.2 4.6 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ31630.1 - 9.2e-08 31.6 1.2 0.00027 20.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ31630.1 - 3.9e-07 30.5 2.3 0.00023 21.6 0.2 3.1 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ31630.1 - 1.7e-06 27.7 2.3 0.00064 19.5 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ31630.1 - 4.5e-06 27.2 9.6 0.0012 19.4 0.2 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ31630.1 - 5.8e-05 23.3 8.5 0.00014 22.1 2.6 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ31630.1 - 0.00028 21.0 5.5 0.00072 19.7 0.3 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 OAJ31630.1 - 0.00099 19.0 8.8 0.0016 18.3 3.1 2.6 1 1 1 2 2 2 1 STI1 domain RPN7 PF10602.9 OAJ31630.1 - 0.021 14.5 0.9 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 OAJ31630.1 - 0.17 12.6 4.9 5.4 7.9 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 OAJ31630.1 - 1.5 7.6 8.3 0.21 10.5 0.6 2.5 1 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Antifungal_pept PF11410.8 OAJ31632.1 - 0.15 12.0 9.1 0.75 9.8 0.3 2.5 2 0 0 2 2 2 0 Antifungal peptide Ornatin PF02088.15 OAJ31632.1 - 0.43 10.4 3.3 0.91 9.4 3.3 1.5 1 0 0 1 1 1 0 Ornatin SnoaL_2 PF12680.7 OAJ31633.1 - 0.0071 17.0 0.1 0.011 16.4 0.1 1.3 1 1 0 1 1 1 1 SnoaL-like domain VHS PF00790.19 OAJ31634.1 - 1.2e-19 70.6 0.0 2.6e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 OAJ31634.1 - 2.7e-06 27.6 0.9 7.6e-06 26.1 0.7 1.9 2 0 0 2 2 2 1 GAT domain mRNA_stabil PF13929.6 OAJ31634.1 - 0.047 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 mRNA stabilisation DUF572 PF04502.13 OAJ31634.1 - 0.85 9.2 12.2 0.11 12.1 8.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) CCDC50_N PF15295.6 OAJ31634.1 - 2.1 8.5 15.7 0.084 13.0 9.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus AAA_11 PF13086.6 OAJ31634.1 - 2.8 7.6 9.9 2.5 7.8 8.8 1.6 1 1 0 1 1 1 0 AAA domain Tfb4 PF03850.14 OAJ31634.1 - 9.5 5.6 8.1 4.2 6.8 4.4 2.0 2 0 0 2 2 2 0 Transcription factor Tfb4 Acyltransferase PF01553.21 OAJ31636.1 - 2.8e-10 39.9 0.0 0.00017 21.2 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase RNA_pol_3_Rpc31 PF11705.8 OAJ31636.1 - 0.47 10.7 11.9 0.41 10.9 9.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 OAJ31636.1 - 4.8 5.3 5.7 8.7 4.4 5.7 1.3 1 0 0 1 1 1 0 Nop14-like family Complex1_49kDa PF00346.19 OAJ31637.1 - 1.4e-122 408.0 0.0 1.6e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Thioredoxin PF00085.20 OAJ31638.1 - 1.2e-25 89.5 0.0 3.6e-21 75.1 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 OAJ31638.1 - 1.8e-06 27.6 0.0 0.00017 21.0 0.0 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 OAJ31638.1 - 8.3e-06 26.2 0.1 2.2e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 OAJ31638.1 - 0.0019 18.3 0.1 0.035 14.3 0.1 2.6 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OAJ31638.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 OAJ31638.1 - 0.068 13.5 0.1 0.38 11.1 0.1 2.2 1 1 0 1 1 1 0 Thioredoxin-like MAS20 PF02064.15 OAJ31639.1 - 1.5e-26 93.0 3.2 1.5e-26 93.0 3.2 2.4 2 1 0 2 2 2 1 MAS20 protein import receptor FAM176 PF14851.6 OAJ31639.1 - 0.96 9.1 4.2 6.6 6.4 1.1 2.9 2 0 0 2 2 2 0 FAM176 family PNP_phzG_C PF10590.9 OAJ31640.1 - 2.8e-20 72.1 3.2 5.3e-20 71.2 3.2 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 OAJ31640.1 - 6.1e-17 61.6 0.1 8.1e-16 58.0 0.1 2.3 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase COPIIcoated_ERV PF07970.12 OAJ31641.1 - 1.2e-77 260.7 0.0 1.8e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 OAJ31641.1 - 4.6e-26 91.0 0.1 1.7e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Proteasome PF00227.26 OAJ31642.1 - 2.9e-52 176.9 0.0 3.6e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ31642.1 - 1e-13 50.6 0.1 2e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNase_H2_suC PF08615.11 OAJ31643.1 - 3.4e-08 33.8 5.1 3.4e-08 33.8 5.1 5.5 3 2 0 3 3 3 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TPR_12 PF13424.6 OAJ31644.1 - 0.015 15.5 0.1 0.047 14.0 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Stealth_CR2 PF11380.8 OAJ31645.1 - 1.8e-16 60.3 0.0 1.3e-05 25.3 0.0 5.2 5 0 0 5 5 5 4 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 OAJ31645.1 - 2.3e-05 24.2 0.2 2.3e-05 24.2 0.2 2.5 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 OAJ31645.1 - 0.00018 21.3 0.0 0.00046 20.0 0.0 1.7 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 OAJ31645.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 ETC_C1_NDUFA4 PF04800.12 OAJ31646.1 - 1.7e-34 117.9 0.1 2.6e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region PAF PF15715.5 OAJ31646.1 - 0.12 13.0 5.0 0.23 12.1 5.0 1.5 1 0 0 1 1 1 0 PCNA-associated factor histone like domain SR-25 PF10500.9 OAJ31646.1 - 0.73 9.4 10.3 0.99 9.0 10.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRIC PF05197.13 OAJ31647.1 - 0.00011 21.8 0.2 0.0013 18.4 0.2 2.2 1 1 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 OAJ31647.1 - 0.055 13.4 9.9 0.2 11.6 1.4 3.5 3 1 0 3 3 3 0 UPF0126 domain PCI PF01399.27 OAJ31648.1 - 6.3e-13 49.1 0.0 1.5e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 PCI domain SSP160 PF06933.11 OAJ31648.1 - 0.033 12.4 2.6 0.044 12.0 2.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Rpn9_C PF18261.1 OAJ31648.1 - 0.051 13.2 0.2 0.092 12.4 0.2 1.4 1 0 0 1 1 1 0 Rpn9 C-terminal helix S-antigen PF05756.11 OAJ31649.1 - 2.5 8.5 5.0 4.5 7.7 5.0 1.4 1 0 0 1 1 1 0 S-antigen protein CTP_transf_like PF01467.26 OAJ31650.1 - 7.2e-23 81.4 0.0 1.2e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like YL1 PF05764.13 OAJ31650.1 - 0.011 15.9 12.5 0.019 15.1 12.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 OAJ31650.1 - 0.025 12.9 11.8 0.034 12.4 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Rota_VP4_MID PF17477.2 OAJ31650.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Rotavirus VP4 membrane interaction domain Nop14 PF04147.12 OAJ31650.1 - 0.29 9.3 16.3 0.45 8.7 16.3 1.2 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 OAJ31650.1 - 1 6.4 7.6 1.4 6.0 7.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DNA_pol_phi PF04931.13 OAJ31650.1 - 3.2 5.7 24.8 4.9 5.1 24.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 OAJ31650.1 - 3.5 7.5 4.8 7.9 6.4 4.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 OAJ31650.1 - 7.1 6.3 13.6 10 5.8 10.9 2.3 2 0 0 2 2 2 0 FAM176 family Atx10homo_assoc PF09759.9 OAJ31651.1 - 1.1e-16 60.7 0.0 4.9e-15 55.3 0.0 2.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Neuropeptide_S PF14993.6 OAJ31651.1 - 0.0045 16.8 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Neuropeptide S precursor protein INTS5_C PF14838.6 OAJ31651.1 - 0.012 14.3 0.5 0.018 13.7 0.5 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Med31 PF05669.12 OAJ31652.1 - 1.5e-28 98.6 0.1 1.8e-28 98.4 0.1 1.1 1 0 0 1 1 1 1 SOH1 DUF1708 PF08101.11 OAJ31653.1 - 2.9e-15 56.4 0.1 2.3e-10 40.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ31653.1 - 0.012 15.4 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 RhoGAP domain SOG2 PF10428.9 OAJ31654.1 - 0.68 9.1 8.5 0.93 8.6 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 OAJ31654.1 - 0.72 9.8 17.7 1.3 9.0 17.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Zip PF02535.22 OAJ31654.1 - 3.4 6.8 11.9 5.1 6.2 11.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SIR2 PF02146.17 OAJ31655.1 - 2.2e-26 92.9 0.0 1.1e-19 71.1 0.0 3.7 3 1 0 3 3 3 2 Sir2 family CpXC PF14353.6 OAJ31655.1 - 0.024 14.7 0.1 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 CpXC protein Histone PF00125.24 OAJ31656.1 - 3.6e-44 150.3 3.0 1.7e-43 148.1 3.0 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ31656.1 - 0.0066 16.6 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ31656.1 - 0.1 12.9 0.1 0.46 10.8 0.1 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 OAJ31656.1 - 0.11 12.8 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 OAJ31656.1 - 0.15 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit BAR PF03114.18 OAJ31657.1 - 2.2e-50 171.6 1.9 2.8e-50 171.2 1.9 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 OAJ31657.1 - 0.00025 20.7 1.3 0.0003 20.4 1.3 1.1 1 0 0 1 1 1 1 Arfaptin-like domain DUF4745 PF15923.5 OAJ31657.1 - 0.034 14.1 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) zf-CCCH PF00642.24 OAJ31658.1 - 6.6e-08 32.3 26.5 1.1e-05 25.2 2.3 4.7 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 OAJ31658.1 - 2.2 9.0 22.2 0.19 12.4 3.8 3.5 1 1 2 3 3 3 0 Torus domain zf-CCCH_4 PF18044.1 OAJ31658.1 - 2.3 8.1 10.4 0.8 9.6 2.3 3.6 3 0 0 3 3 3 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 OAJ31658.1 - 3.1 8.0 24.9 0.76 9.9 4.6 4.5 4 0 0 4 4 4 0 Zinc finger domain Chalcone_2 PF16035.5 OAJ31659.1 - 3.2e-37 128.3 0.5 6.6e-36 124.0 0.5 2.5 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 OAJ31659.1 - 6.8e-05 23.0 0.0 0.00047 20.3 0.1 2.0 1 1 1 2 2 2 1 Chalcone isomerase-like MCM PF00493.23 OAJ31660.1 - 4.7e-105 349.7 0.0 7.2e-105 349.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ31660.1 - 6.6e-34 116.5 0.0 1.2e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ31660.1 - 9.1e-29 99.7 0.8 2.3e-28 98.5 0.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ31660.1 - 1.1e-13 51.7 0.0 2.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 OAJ31660.1 - 1.8e-06 27.5 0.0 0.00045 19.7 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 OAJ31660.1 - 6.4e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 OAJ31660.1 - 0.00012 21.9 0.0 0.0017 18.2 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ31660.1 - 0.031 14.0 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 OAJ31660.1 - 0.11 13.1 1.0 0.32 11.7 0.4 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 OAJ31660.1 - 0.11 12.9 0.1 0.64 10.4 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Telomere_reg-2 PF10193.9 OAJ31661.1 - 8.9e-27 93.7 0.0 4.1e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Mito_carr PF00153.27 OAJ31662.1 - 2.7e-56 187.5 3.0 7.1e-18 64.3 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein SNF2_N PF00176.23 OAJ31663.1 - 2.4e-74 250.1 0.0 5.1e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 OAJ31663.1 - 9.5e-37 125.5 0.2 9.5e-37 125.5 0.2 2.9 5 0 0 5 5 4 1 SLIDE HAND PF09110.11 OAJ31663.1 - 5.5e-32 110.8 4.2 5.5e-32 110.8 4.2 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 OAJ31663.1 - 8.8e-18 64.7 0.0 1.4e-16 60.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ31663.1 - 1.4e-10 41.5 0.0 8.9e-10 38.8 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ31663.1 - 4e-06 26.2 0.0 4e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 Myb_DNA-binding PF00249.31 OAJ31663.1 - 3.1e-05 24.1 0.0 0.055 13.7 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.29 OAJ31663.1 - 3.5e-05 23.6 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HWE_HK PF07536.14 OAJ31663.1 - 0.0018 18.9 0.7 0.3 11.8 0.0 3.0 2 0 0 2 2 2 1 HWE histidine kinase AAA_14 PF13173.6 OAJ31663.1 - 0.0068 16.4 0.1 0.024 14.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain DBINO PF13892.6 OAJ31663.1 - 0.0078 16.6 5.8 0.0078 16.6 5.8 3.8 4 0 0 4 4 4 1 DNA-binding domain AAA_22 PF13401.6 OAJ31663.1 - 0.075 13.3 0.1 0.41 10.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Ribosomal_L28e PF01778.17 OAJ31664.1 - 1.6e-23 83.7 0.3 2.6e-23 82.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family Citrate_ly_lig PF08218.11 OAJ31664.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Sec1 PF00995.23 OAJ31665.1 - 2.4e-13 50.2 0.0 2.5e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3182 PF11379.8 OAJ31665.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) CBFD_NFYB_HMF PF00808.23 OAJ31666.1 - 6.7e-21 74.3 0.1 1.2e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 OAJ31666.1 - 0.0024 18.2 4.3 0.0032 17.8 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 OAJ31666.1 - 0.078 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Prefoldin PF02996.17 OAJ31667.1 - 3.3e-30 104.5 0.0 4.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit NBP1 PF08537.10 OAJ31667.1 - 0.019 14.4 1.9 0.028 13.8 1.9 1.3 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 Cortex-I_coil PF09304.10 OAJ31667.1 - 0.037 14.3 3.4 0.3 11.3 0.3 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil NADH_4Fe-4S PF10589.9 OAJ31667.1 - 0.082 13.0 0.4 9 6.4 0.1 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Rx_N PF18052.1 OAJ31667.1 - 0.17 12.2 3.8 3.5 8.0 0.7 2.5 1 1 1 2 2 2 0 Rx N-terminal domain Spore_GerAC PF05504.11 OAJ31668.1 - 0.056 13.7 2.0 0.094 12.9 2.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Spc7 PF08317.11 OAJ31668.1 - 0.079 11.8 17.4 0.059 12.2 15.9 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAJ31668.1 - 0.21 11.7 14.1 0.34 11.0 14.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2570 PF10828.8 OAJ31668.1 - 6.6 6.6 13.5 4 7.3 9.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) DivIC PF04977.15 OAJ31668.1 - 8.6 6.2 17.6 3.5 7.5 4.9 2.6 1 1 1 2 2 2 0 Septum formation initiator Mito_carr PF00153.27 OAJ31669.1 - 2.8e-29 100.9 5.2 4.2e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps53_N PF04100.12 OAJ31670.1 - 5.8e-86 288.8 3.3 1e-85 288.0 3.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 OAJ31670.1 - 0.0002 21.3 0.0 0.0014 18.6 0.0 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps54_N PF10475.9 OAJ31670.1 - 0.0033 16.8 5.9 0.0066 15.8 5.9 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RecG_N PF17190.4 OAJ31670.1 - 0.11 13.2 0.8 0.37 11.5 0.8 2.0 1 0 0 1 1 1 0 RecG N-terminal helical domain Sec5 PF15469.6 OAJ31670.1 - 0.17 11.7 2.9 0.38 10.5 2.9 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 Fib_alpha PF08702.10 OAJ31670.1 - 5.1 7.3 5.3 16 5.7 4.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 OAJ31670.1 - 5.1 7.1 9.3 10 6.1 7.0 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Copper-fist PF00649.18 OAJ31672.1 - 6e-15 54.4 0.9 1.6e-14 53.1 0.9 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain HAT PF02184.16 OAJ31673.1 - 1.4e-17 63.3 56.7 2.9e-09 36.7 0.6 14.3 16 0 0 16 16 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 OAJ31673.1 - 4.6e-15 55.0 35.5 0.0018 18.9 0.1 11.4 5 2 9 14 14 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ31673.1 - 8.3e-13 48.6 1.2 0.00073 20.0 0.0 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat Suf PF05843.14 OAJ31673.1 - 2.5e-09 37.5 10.2 0.00027 21.0 0.1 5.3 2 2 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 OAJ31673.1 - 2.6e-07 30.2 7.0 3.1 8.1 0.0 7.4 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ31673.1 - 1.8e-06 27.7 0.7 0.49 10.7 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ31673.1 - 0.0014 18.3 1.0 78 3.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ31673.1 - 0.0036 17.6 0.1 0.42 11.1 0.0 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 OAJ31673.1 - 0.016 15.3 7.2 0.47 10.6 0.3 4.7 3 1 1 4 4 4 0 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.6 OAJ31673.1 - 0.027 14.5 6.6 21 5.5 0.0 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat ECSIT PF06239.11 OAJ31673.1 - 0.034 13.3 2.8 0.44 9.6 0.4 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_15 PF13429.6 OAJ31673.1 - 0.064 12.5 20.0 0.12 11.6 0.0 5.6 2 2 4 6 6 6 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 OAJ31673.1 - 0.15 12.0 16.1 4.7 7.2 0.1 6.5 6 2 0 6 6 6 0 Mad3/BUB1 homology region 1 PcfK PF14058.6 OAJ31673.1 - 0.28 11.5 2.9 0.86 9.9 0.8 2.5 2 0 0 2 2 2 0 PcfK-like protein CENP-B_dimeris PF09026.10 OAJ31673.1 - 7.3 7.1 18.7 7.9 6.9 1.5 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 OAJ31673.1 - 8.2 5.6 8.7 4.1 6.6 2.5 2.2 2 0 0 2 2 2 0 NOA36 protein Acetyltransf_1 PF00583.25 OAJ31675.1 - 4.7e-07 30.0 0.0 6.8e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ31675.1 - 0.00069 20.0 0.0 0.0024 18.3 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain 6PF2K PF01591.18 OAJ31676.1 - 2.8e-69 232.8 0.0 4e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 OAJ31676.1 - 1.6e-33 116.0 0.0 4.8e-33 114.5 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 OAJ31676.1 - 1.6e-08 34.8 0.0 3.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 OAJ31676.1 - 0.0056 17.1 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain GBP PF02263.19 OAJ31676.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain TIG PF01833.24 OAJ31677.1 - 1.2e-12 47.7 0.6 9.9e-11 41.6 1.3 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 OAJ31677.1 - 9e-10 38.6 0.3 3.6e-09 36.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ31677.1 - 5e-08 33.3 1.1 1.5e-07 31.8 1.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ31677.1 - 3.4e-07 30.8 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ31677.1 - 4.8e-07 29.6 1.1 0.0028 18.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 OAJ31677.1 - 2.2e-06 27.9 2.6 0.03 14.8 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Spt20 PF12090.8 OAJ31677.1 - 2.4 7.7 8.4 6.8 6.2 8.4 1.7 1 0 0 1 1 1 0 Spt20 family Kinesin PF00225.23 OAJ31678.1 - 6.5e-110 367.2 0.0 6.5e-110 367.2 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ31678.1 - 3.1e-26 92.1 0.0 1.5e-25 89.9 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding ATG16 PF08614.11 OAJ31678.1 - 8e-05 23.0 12.5 8e-05 23.0 12.5 4.4 1 1 2 3 3 3 1 Autophagy protein 16 (ATG16) Sox_N PF12444.8 OAJ31678.1 - 0.017 16.2 2.0 0.19 12.9 0.0 3.8 3 0 0 3 3 3 0 Sox developmental protein N terminal HOOK PF05622.12 OAJ31678.1 - 6 4.9 79.8 0.16 10.1 24.4 3.2 1 1 1 2 2 2 0 HOOK protein Ribosomal_S21e PF01249.18 OAJ31679.1 - 1.7e-35 121.0 0.0 1.9e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FliMN_C PF01052.20 OAJ31679.1 - 0.039 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term eIF-3_zeta PF05091.12 OAJ31680.1 - 0.73 8.7 22.4 1 8.2 22.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.6 OAJ31680.1 - 0.75 8.1 1.9 0.73 8.2 1.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.15 OAJ31680.1 - 1.4 7.8 7.5 2.1 7.2 7.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Exonuc_VII_L PF02601.15 OAJ31680.1 - 1.5 8.4 22.3 1.5 8.4 0.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Spt20 PF12090.8 OAJ31680.1 - 2.6 7.6 48.7 1.5 8.4 46.0 2.0 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 OAJ31680.1 - 3 7.6 19.2 0.42 10.4 15.2 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Baculo_PP31 PF05311.11 OAJ31680.1 - 3.1 7.2 11.9 7 6.0 11.9 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1980 PF09323.10 OAJ31680.1 - 3.7 7.4 9.2 6.6 6.6 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF913 PF06025.12 OAJ31680.1 - 5.9 5.8 10.9 13 4.7 10.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 OAJ31680.1 - 7.1 6.3 12.2 14 5.3 12.2 1.5 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 OAJ31680.1 - 7.5 5.9 18.0 14 5.0 18.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PIP5K PF01504.18 OAJ31680.1 - 8.7 5.5 12.6 18 4.4 12.6 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DPBB_1 PF03330.18 OAJ31681.1 - 2.1e-05 24.7 0.0 4.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 OAJ31681.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Barwin family PPP4R2 PF09184.11 OAJ31681.1 - 0.96 9.0 13.7 0.8 9.2 2.3 2.3 2 0 0 2 2 2 0 PPP4R2 Sybindin PF04099.12 OAJ31682.1 - 1.4e-39 135.3 0.0 1.5e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 OAJ31682.1 - 8.9e-07 29.1 0.0 9.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PCNA_N PF00705.18 OAJ31682.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain NRDD PF13597.6 OAJ31682.1 - 0.23 10.2 0.0 0.26 10.0 0.0 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Asp PF00026.23 OAJ31683.1 - 6.6e-43 147.3 0.0 8.4e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ31683.1 - 4.7e-10 40.0 2.9 5.9e-09 36.4 1.5 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal NTF2 PF02136.20 OAJ31684.1 - 5.7e-30 104.4 0.0 9e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 OAJ31684.1 - 0.00015 21.5 0.0 0.00026 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 OAJ31684.1 - 0.0033 16.7 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RRM_occluded PF16842.5 OAJ31684.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sel1 PF08238.12 OAJ31686.1 - 3.7e-36 122.7 22.3 1.8e-06 28.4 0.4 8.5 8 0 0 8 8 8 7 Sel1 repeat HLH PF00010.26 OAJ31686.1 - 1.8e-14 53.4 3.8 9.3e-09 35.1 0.0 3.0 2 1 1 3 3 3 2 Helix-loop-helix DNA-binding domain EF-hand_1 PF00036.32 OAJ31687.1 - 5.9e-42 138.1 13.0 1.5e-10 39.8 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 OAJ31687.1 - 4e-36 123.3 2.7 2.5e-18 66.3 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 OAJ31687.1 - 1.4e-31 105.7 7.4 1.8e-09 36.8 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ31687.1 - 3.8e-31 106.7 10.9 1.5e-14 53.5 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 OAJ31687.1 - 6.1e-27 91.9 9.3 9.9e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 OAJ31687.1 - 2.6e-16 59.7 0.2 2.1e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 OAJ31687.1 - 3.8e-10 39.7 0.6 3.5e-05 23.7 0.3 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 OAJ31687.1 - 1.7e-08 34.8 0.0 0.00092 19.5 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 OAJ31687.1 - 3.5e-06 27.0 1.7 0.041 13.9 0.0 3.5 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 OAJ31687.1 - 6.4e-06 27.0 0.0 0.0051 17.7 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 OAJ31687.1 - 0.00013 22.1 5.6 0.017 15.3 0.7 3.1 1 1 3 4 4 4 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 OAJ31687.1 - 0.00014 21.9 0.3 0.00051 20.1 0.1 2.0 2 1 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 OAJ31687.1 - 0.00068 19.3 1.2 0.00079 19.1 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 OAJ31687.1 - 0.0013 18.7 1.5 0.47 10.4 0.0 3.4 1 1 3 4 4 4 1 Caleosin related protein Poly_export PF02563.16 OAJ31687.1 - 0.0034 17.6 0.1 0.69 10.2 0.0 2.9 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 OAJ31687.1 - 0.0037 17.7 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 OAJ31687.1 - 0.0052 16.7 0.2 1.3 9.0 0.0 2.1 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.10 OAJ31687.1 - 0.0075 16.4 0.2 0.12 12.5 0.1 2.2 2 1 0 2 2 2 1 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 OAJ31687.1 - 0.0091 16.3 0.3 3.8 7.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 OAJ31687.1 - 0.013 14.1 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 OAJ31687.1 - 0.025 14.6 0.5 18 5.5 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 dCache_2 PF08269.11 OAJ31687.1 - 0.034 13.3 0.1 0.61 9.2 0.1 2.2 1 1 0 1 1 1 0 Cache domain SurA_N_2 PF13623.6 OAJ31687.1 - 0.039 13.8 0.6 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 OAJ31687.1 - 0.061 13.7 0.1 15 6.0 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain DUF1811 PF08838.10 OAJ31687.1 - 0.071 13.3 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Fe_hyd_lg_C PF02906.14 OAJ31687.1 - 0.076 12.7 0.2 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RuvA_C PF07499.13 OAJ31687.1 - 0.15 12.5 0.1 16 6.1 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Rxt3 PF08642.10 OAJ31688.1 - 1.9e-16 61.0 0.0 1.9e-16 61.0 0.0 7.3 4 3 0 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 OAJ31688.1 - 0.023 14.8 0.0 0.077 13.1 0.0 1.8 1 0 0 1 1 1 0 LCCL domain DDE_1 PF03184.19 OAJ31689.1 - 7.2e-21 74.6 0.0 1.5e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 OAJ31689.1 - 1.1e-08 35.0 0.0 4.9e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 OAJ31689.1 - 0.0011 18.7 0.1 0.0044 16.8 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease SH3_1 PF00018.28 OAJ31690.1 - 9.5e-25 86.0 0.0 2e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 OAJ31690.1 - 2.4e-14 52.9 0.0 2.6e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 OAJ31690.1 - 1.2e-13 50.5 0.0 9.3e-09 34.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 OAJ31690.1 - 1.3e-10 41.2 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 OAJ31690.1 - 7.4e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Sulf_transp PF04143.14 OAJ31691.1 - 3.4e-06 26.9 18.8 0.00026 20.7 4.3 3.5 2 1 1 3 3 3 3 Sulphur transport CD20 PF04103.15 OAJ31691.1 - 0.01 16.0 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 CD20-like family RPN1_RPN2_N PF17781.1 OAJ31692.1 - 2.2e-114 382.0 0.0 5.8e-114 380.6 0.0 1.8 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 OAJ31692.1 - 2.8e-28 97.7 0.4 8.2e-28 96.2 0.0 2.0 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 OAJ31692.1 - 1.3e-15 56.9 18.3 0.0011 19.3 0.0 8.3 8 0 0 8 8 8 5 Proteasome/cyclosome repeat T2SSF PF00482.23 OAJ31692.1 - 0.12 12.3 0.9 15 5.5 0.0 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FYDLN_acid PF09538.10 OAJ31692.1 - 1.9 9.2 17.8 1.8 9.3 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HEAT_2 PF13646.6 OAJ31692.1 - 8.6 6.8 13.6 1.5 9.3 0.1 4.9 5 1 0 5 5 5 0 HEAT repeats RRM_1 PF00076.22 OAJ31693.1 - 2.5e-34 116.9 0.0 7.7e-20 70.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 OAJ31693.1 - 9.3e-11 42.7 2.1 2.1e-09 38.4 2.1 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 OAJ31693.1 - 3.1e-06 27.0 0.0 0.036 13.9 0.0 2.9 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 OAJ31693.1 - 0.00046 19.8 0.0 0.1 12.2 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ31693.1 - 0.0015 18.5 0.0 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 OAJ31693.1 - 0.018 15.1 0.0 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ANAPC4_WD40 PF12894.7 OAJ31694.1 - 1e-10 41.7 0.0 9.7e-05 22.6 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ31694.1 - 2.6e-06 28.1 3.6 0.026 15.4 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PD40 PF07676.12 OAJ31694.1 - 3.9e-05 23.5 0.3 0.92 9.5 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat His_Phos_1 PF00300.22 OAJ31695.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 OAJ31696.1 - 1.2e-15 57.6 24.5 0.0026 18.6 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 OAJ31696.1 - 1.6e-15 57.3 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 OAJ31696.1 - 0.0085 16.4 0.0 16 5.9 0.0 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 OAJ31696.1 - 0.056 13.9 2.4 1.9 9.1 0.1 4.4 5 0 0 5 5 5 0 PQQ-like domain TBCC PF07986.12 OAJ31697.1 - 2.3e-14 53.2 1.4 4.9e-13 48.9 1.1 2.2 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 OAJ31697.1 - 0.0066 16.1 0.5 0.011 15.4 0.5 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PhoLip_ATPase_C PF16212.5 OAJ31698.1 - 1.6e-49 168.9 21.2 1.6e-49 168.9 21.2 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 OAJ31698.1 - 2.1e-18 65.8 2.9 5.7e-18 64.4 2.9 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 OAJ31698.1 - 2.4e-14 54.1 2.1 5.3e-09 36.7 0.6 2.8 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 OAJ31698.1 - 1.4e-13 50.7 0.9 2.7e-05 23.8 0.2 3.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 OAJ31698.1 - 2e-10 40.6 0.0 1.1e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 OAJ31698.1 - 0.0022 17.8 0.1 0.0057 16.4 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UBA2_C PF16195.5 OAJ31698.1 - 8 7.2 8.5 0.46 11.2 1.5 2.4 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus Acetyltransf_1 PF00583.25 OAJ31699.1 - 2.2e-10 40.8 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 OAJ31699.1 - 3.7e-05 24.1 0.0 6.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 OAJ31699.1 - 0.00097 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 OAJ31699.1 - 0.0034 18.1 0.0 0.0058 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ31699.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein TEA PF01285.18 OAJ31703.1 - 2.3e-28 98.0 0.0 4.6e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Lipase_GDSL_2 PF13472.6 OAJ31705.1 - 1.8e-24 87.2 0.0 2.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 OAJ31705.1 - 4.9e-15 56.0 0.0 8e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CHORD PF04968.12 OAJ31706.1 - 2.9e-41 140.0 14.8 2.3e-21 76.3 4.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 OAJ31706.1 - 2.2e-08 35.0 0.0 3.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 OAJ31706.1 - 0.022 14.6 4.9 0.14 12.0 0.4 2.8 2 0 0 2 2 2 0 BTK motif DUF2013 PF09431.10 OAJ31708.1 - 1.5e-53 180.6 2.1 2.8e-53 179.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) XAP5 PF04921.14 OAJ31709.1 - 2.5e-89 299.4 6.6 2.5e-89 299.4 6.6 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator Mucin PF01456.17 OAJ31709.1 - 0.2 11.7 10.2 0.3 11.1 10.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S64 PF08192.11 OAJ31709.1 - 0.46 8.9 7.3 0.57 8.6 7.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 OAJ31709.1 - 9.6 4.8 9.7 12 4.4 9.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_tran PF00005.27 OAJ31713.1 - 2e-14 54.3 0.0 1.6e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 OAJ31713.1 - 3.4e-07 30.4 2.0 0.0015 18.4 0.5 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ31713.1 - 0.0014 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 OAJ31713.1 - 0.0036 17.8 0.0 0.0053 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 OAJ31713.1 - 0.0041 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 OAJ31713.1 - 0.0042 17.3 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 OAJ31713.1 - 0.012 15.2 0.2 0.074 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 OAJ31713.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 OAJ31713.1 - 0.024 14.1 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 OAJ31713.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.10 OAJ31713.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Guanylate_kin PF00625.21 OAJ31713.1 - 0.028 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase AAA_16 PF13191.6 OAJ31713.1 - 0.058 13.8 0.3 0.092 13.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 OAJ31713.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 OAJ31713.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 OAJ31713.1 - 0.086 13.0 0.1 0.22 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 OAJ31713.1 - 0.11 12.7 0.0 0.46 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 OAJ31713.1 - 0.14 12.6 0.0 0.39 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 OAJ31713.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 OAJ31713.1 - 0.2 11.2 0.2 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UCH PF00443.29 OAJ31714.1 - 3.2e-42 144.8 0.0 5.4e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 OAJ31714.1 - 5.3e-21 74.7 5.5 1.2e-17 64.0 1.3 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 OAJ31714.1 - 1.6e-19 69.4 1.3 2.7e-10 39.9 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 OAJ31714.1 - 2.4e-18 65.7 10.3 5.5e-17 61.3 4.8 3.7 2 1 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 OAJ31714.1 - 3.2e-18 66.4 0.0 3.1e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RVT_1 PF00078.27 OAJ31716.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2573 PF10835.8 OAJ31716.1 - 0.11 12.8 0.0 7.8 6.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2573) Glyco_hydro_43 PF04616.14 OAJ31718.1 - 1.2e-35 123.3 0.5 1.4e-35 123.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AP2 PF00847.20 OAJ31718.1 - 0.13 12.5 0.2 0.27 11.5 0.2 1.5 1 0 0 1 1 1 0 AP2 domain LIAS_N PF16881.5 OAJ31719.1 - 1.9e-15 57.2 0.1 6.3e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 OAJ31719.1 - 3.6e-14 53.5 0.1 5.7e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily PP2C PF00481.21 OAJ31721.1 - 7.4e-35 120.8 0.0 2e-32 112.8 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C Radical_SAM_C PF16199.5 OAJ31722.1 - 2e-31 107.8 0.0 4.3e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 OAJ31722.1 - 9.9e-19 68.3 0.4 8.2e-18 65.3 0.1 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 OAJ31722.1 - 9.1e-08 32.3 0.1 2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 OAJ31722.1 - 8.1e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 OAJ31722.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Methyltr_RsmB-F PF01189.17 OAJ31723.1 - 8.3e-72 241.0 0.0 1.2e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 OAJ31723.1 - 5.5e-09 36.4 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 OAJ31723.1 - 0.0012 19.0 0.0 0.0079 16.3 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 OAJ31723.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 OAJ31723.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 OAJ31723.1 - 0.0065 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.9 OAJ31723.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) SDA1 PF05285.12 OAJ31723.1 - 1.3 8.4 49.2 0.039 13.4 21.9 2.2 2 0 0 2 2 2 0 SDA1 Mannosyl_trans3 PF11051.8 OAJ31724.1 - 0.00018 21.0 0.0 0.0023 17.3 0.0 2.4 2 1 0 2 2 2 1 Mannosyltransferase putative ECH_1 PF00378.20 OAJ31726.1 - 8.1e-16 58.1 0.4 2.9e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Formyl_trans_N PF00551.19 OAJ31726.1 - 0.05 13.3 0.0 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Formyl transferase Memo PF01875.17 OAJ31730.1 - 2e-70 237.0 0.0 6.5e-70 235.4 0.0 1.7 1 1 0 1 1 1 1 Memo-like protein zf-C2H2 PF00096.26 OAJ31731.1 - 2.9e-20 71.5 22.5 0.0001 22.5 2.5 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ31731.1 - 3.9e-18 65.0 14.2 0.00019 21.7 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 OAJ31731.1 - 4.6e-11 42.6 20.9 0.013 16.3 0.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger FOXP-CC PF16159.5 OAJ31731.1 - 0.00046 20.8 6.2 0.43 11.3 0.1 3.9 2 1 2 4 4 3 2 FOXP coiled-coil domain TFIIA PF03153.13 OAJ31731.1 - 0.0017 18.5 1.1 0.0017 18.5 1.1 4.7 2 2 2 5 5 3 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_jaz PF12171.8 OAJ31731.1 - 0.01 16.1 5.7 3 8.3 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 OAJ31731.1 - 0.14 12.9 6.4 0.063 14.0 1.0 2.5 1 1 2 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 OAJ31731.1 - 0.16 12.1 1.5 13 5.9 0.6 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger zf-met PF12874.7 OAJ31731.1 - 1 9.9 11.8 6.1 7.4 0.4 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.10 OAJ31731.1 - 1.1 10.0 12.4 0.18 12.5 6.7 2.8 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 OAJ31731.1 - 3.6 5.7 9.5 5.7 5.0 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_6 PF13912.6 OAJ31731.1 - 4.3 7.5 18.0 0.67 10.0 0.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger PPP4R2 PF09184.11 OAJ31731.1 - 6.5 6.3 5.6 15 5.0 5.6 1.6 1 0 0 1 1 1 0 PPP4R2 Chromo PF00385.24 OAJ31732.1 - 1.2e-14 54.0 2.3 1.2e-14 54.0 2.3 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 OAJ31732.1 - 1.6e-13 50.5 0.0 2.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain PCMT PF01135.19 OAJ31733.1 - 5.9e-64 215.7 0.0 2.2e-62 210.5 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 OAJ31733.1 - 0.049 13.5 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31733.1 - 0.07 12.9 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PIG-H PF10181.9 OAJ31734.1 - 1.4e-08 34.5 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Mito_carr PF00153.27 OAJ31735.1 - 2.2e-49 165.3 4.3 2.6e-18 65.7 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 OAJ31735.1 - 0.0025 17.0 3.9 0.61 9.2 0.1 3.3 2 1 0 3 3 3 3 Gammaproteobacterial serine protease DNA_ligase_A_M PF01068.21 OAJ31736.1 - 3.8e-18 65.9 0.0 9.3e-08 32.0 0.0 4.2 3 1 0 3 3 3 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 OAJ31736.1 - 2.5e-06 28.0 0.1 7.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus Pox_F12L PF03337.13 OAJ31736.1 - 0.14 10.3 0.0 0.25 9.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus F12L protein PIP5K PF01504.18 OAJ31737.1 - 6.3e-43 147.0 0.1 1.8e-33 116.0 0.0 3.2 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 OAJ31737.1 - 7.2e-27 94.2 0.2 1.2e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 OAJ31737.1 - 1.5e-15 57.1 9.3 1.5e-15 57.1 9.3 1.9 2 0 0 2 2 2 1 FYVE zinc finger Spt20 PF12090.8 OAJ31737.1 - 5.8 6.4 10.1 0.15 11.6 3.3 1.7 2 0 0 2 2 2 0 Spt20 family LIP PF03583.14 OAJ31738.1 - 1.5e-45 155.8 0.1 2e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ31738.1 - 0.00012 21.6 0.2 0.0076 15.7 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 OAJ31738.1 - 0.084 12.1 0.6 5.9 6.1 0.0 2.7 3 1 0 3 3 3 0 Serine aminopeptidase, S33 bZIP_1 PF00170.21 OAJ31740.1 - 4.1e-07 30.0 25.7 4.4e-07 29.9 8.2 3.1 2 1 1 3 3 3 2 bZIP transcription factor Hap4_Hap_bind PF10297.9 OAJ31740.1 - 1.6e-06 28.1 4.8 1.6e-06 28.1 4.8 2.8 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 SNF2_N PF00176.23 OAJ31741.1 - 6.3e-63 212.6 1.7 1.2e-62 211.7 1.7 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 OAJ31741.1 - 1.8e-51 174.0 20.6 1.8e-51 174.0 20.6 2.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 OAJ31741.1 - 9.7e-17 61.3 0.0 2.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ31741.1 - 1.1e-06 28.8 0.0 2.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 OAJ31741.1 - 0.025 13.7 2.3 0.03 13.5 0.0 2.1 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Paramyx_P_V_C PF03210.13 OAJ31741.1 - 0.69 9.7 5.5 3.2 7.5 1.7 2.6 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal RT_RNaseH_2 PF17919.1 OAJ31744.1 - 2.5e-31 107.7 0.0 6.4e-31 106.4 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 OAJ31744.1 - 3.9e-27 94.6 0.0 9.7e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 OAJ31744.1 - 1.1e-20 74.1 0.0 2.2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ31744.1 - 8.6e-15 55.0 0.0 2.8e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 OAJ31744.1 - 3.2e-09 36.8 0.3 7.2e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve_3 PF13683.6 OAJ31744.1 - 0.018 14.8 0.0 0.063 13.1 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain Use1 PF09753.9 OAJ31744.1 - 1.1 9.0 7.2 3.1 7.4 7.2 1.7 1 0 0 1 1 1 0 Membrane fusion protein Use1 CBM60 PF16841.5 OAJ31745.1 - 0.12 12.9 0.0 9.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding Prenyltrans PF00432.21 OAJ31746.1 - 1.7e-36 123.6 12.2 6.4e-12 45.0 0.2 5.7 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 OAJ31746.1 - 0.066 12.3 0.1 1.3 8.0 0.1 2.8 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain LUC7 PF03194.15 OAJ31747.1 - 1.8e-70 237.5 1.6 2.7e-70 236.9 1.6 1.2 1 0 0 1 1 1 1 LUC7 N_terminus ArgJ PF01960.18 OAJ31748.1 - 8.6e-131 436.1 0.0 1.3e-130 435.6 0.0 1.2 1 0 0 1 1 1 1 ArgJ family Hist_deacetyl PF00850.19 OAJ31749.1 - 2e-82 277.1 0.0 2.5e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain PPR_2 PF13041.6 OAJ31750.1 - 2.7e-30 104.3 5.4 4.9e-11 42.7 0.2 8.4 7 1 3 10 10 10 5 PPR repeat family PPR PF01535.20 OAJ31750.1 - 1.6e-26 90.7 7.0 2.6e-06 27.3 0.1 11.3 12 0 0 12 12 12 4 PPR repeat PPR_3 PF13812.6 OAJ31750.1 - 2e-15 56.6 0.1 9.5e-06 25.6 0.1 5.5 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 OAJ31750.1 - 1.4e-14 54.0 6.2 4.5e-12 45.8 1.1 3.8 3 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 OAJ31750.1 - 7.8e-10 38.3 6.8 0.001 18.7 0.0 6.2 8 0 0 8 8 8 2 PPR repeat TPR_7 PF13176.6 OAJ31750.1 - 0.00096 19.0 0.1 7.4 6.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DNA_Packaging PF11053.8 OAJ31750.1 - 0.025 14.5 0.1 0.087 12.7 0.1 1.9 1 0 0 1 1 1 0 Terminase DNA packaging enzyme TPR_8 PF13181.6 OAJ31750.1 - 0.11 12.7 4.1 2.4 8.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ31750.1 - 0.18 12.4 14.9 16 6.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat AA_kinase PF00696.28 OAJ31751.1 - 1.8e-36 125.9 0.0 4.9e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.25 OAJ31751.1 - 3.6e-07 29.8 0.1 0.015 15.0 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 OAJ31751.1 - 7.9e-06 25.6 0.2 7.9e-06 25.6 0.2 2.1 2 0 0 2 2 2 1 ACT domain CopC PF04234.12 OAJ31752.1 - 0.0072 17.3 1.4 0.0079 17.2 0.2 1.6 2 0 0 2 2 2 1 CopC domain FLYWCH_u PF16662.5 OAJ31752.1 - 0.28 11.3 4.2 0.25 11.4 0.6 2.1 2 0 0 2 2 2 0 FLYWCH-type zinc finger-containing protein 1 Ssu72 PF04722.13 OAJ31753.1 - 2.9e-85 284.7 0.0 3.3e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DNA_repr_REX1B PF14966.6 OAJ31754.1 - 0.00088 19.9 2.0 0.28 11.8 0.1 3.1 2 1 0 2 2 2 1 DNA repair REX1-B TMF_TATA_bd PF12325.8 OAJ31754.1 - 0.007 16.6 2.9 0.017 15.3 2.9 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF5132 PF17195.4 OAJ31754.1 - 0.5 10.5 2.8 1.2 9.3 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) DUF4763 PF15960.5 OAJ31754.1 - 1.9 7.7 9.7 0.056 12.7 3.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF4407 PF14362.6 OAJ31754.1 - 8.1 5.7 11.0 0.31 10.3 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SET PF00856.28 OAJ31755.1 - 0.0031 17.9 0.0 0.0049 17.3 0.0 1.4 1 0 0 1 1 1 1 SET domain Methyltransf_13 PF08421.11 OAJ31755.1 - 0.094 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative zinc binding domain HMG_box PF00505.19 OAJ31756.1 - 6.7e-14 52.1 1.7 8.5e-14 51.7 0.4 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ31756.1 - 1.3e-09 38.5 0.2 3e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain DASH_Dad4 PF08650.10 OAJ31757.1 - 1.5e-24 85.7 0.0 1.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 OAJ31757.1 - 0.015 15.5 0.2 0.019 15.1 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 PRMT5_TIM PF17285.2 OAJ31758.1 - 1.6e-58 198.0 0.0 2.5e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 OAJ31758.1 - 1.4e-57 194.3 0.0 2.2e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 OAJ31758.1 - 8e-52 175.7 0.0 1.1e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 OAJ31758.1 - 0.00054 20.6 0.0 0.0018 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ31758.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ31758.1 - 0.013 16.1 0.0 0.041 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ceramidase PF05875.12 OAJ31759.1 - 4.3e-70 236.1 4.6 5e-70 235.9 4.6 1.0 1 0 0 1 1 1 1 Ceramidase ADH_N PF08240.12 OAJ31761.1 - 5.7e-31 106.6 0.2 1e-30 105.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ31761.1 - 3.5e-25 88.5 0.1 5.5e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 OAJ31761.1 - 9e-06 25.3 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 OAJ31761.1 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 OAJ31761.1 - 0.0018 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 OAJ31761.1 - 0.0026 18.8 0.0 0.0048 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 OAJ31761.1 - 0.0026 18.4 0.0 0.0063 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 OAJ31761.1 - 0.0032 17.7 0.2 0.0058 16.9 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_N_assoc PF13823.6 OAJ31761.1 - 0.14 12.1 1.1 0.37 10.8 1.1 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Thiamine_BP PF01910.17 OAJ31762.1 - 6.5e-21 74.1 0.0 8e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 OAJ31762.1 - 0.005 17.3 0.0 0.0073 16.8 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family F-box-like PF12937.7 OAJ31763.1 - 0.0099 15.8 1.5 0.21 11.5 0.2 2.5 2 0 0 2 2 2 2 F-box-like WD40 PF00400.32 OAJ31765.1 - 2e-09 37.9 9.8 0.019 15.8 1.0 5.4 4 1 1 5 5 5 3 WD domain, G-beta repeat OEP PF02321.18 OAJ31765.1 - 0.0051 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Outer membrane efflux protein UQ_con PF00179.26 OAJ31766.1 - 3.8e-22 78.4 0.0 7.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 OAJ31766.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain IBR PF01485.21 OAJ31766.1 - 0.019 15.2 0.5 0.047 13.9 0.5 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ALMT PF11744.8 OAJ31766.1 - 0.38 9.5 2.8 0.67 8.7 2.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter BUD22 PF09073.10 OAJ31766.1 - 1.2 8.4 29.1 0.056 12.8 9.9 2.9 3 0 0 3 3 3 0 BUD22 Neur_chan_memb PF02932.16 OAJ31766.1 - 3.9 7.5 5.0 8.7 6.3 5.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4050 PF13259.6 OAJ31766.1 - 4.7 7.5 6.9 9.5 6.5 2.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) RNA_pol_Rpb2_6 PF00562.28 OAJ31767.1 - 7.3e-127 423.6 0.1 1.1e-126 423.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ31767.1 - 2.3e-59 200.3 0.1 3.6e-59 199.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ31767.1 - 1.5e-33 116.0 0.2 3.1e-33 115.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ31767.1 - 1.4e-29 102.4 0.1 3.3e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 OAJ31767.1 - 3.6e-25 88.0 0.3 8e-25 86.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 OAJ31767.1 - 2.1e-20 72.6 0.0 4.9e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 OAJ31767.1 - 4.7e-09 36.7 1.7 1.8e-08 34.8 1.7 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Aldo_ket_red PF00248.21 OAJ31767.1 - 0.046 12.9 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family Mis14 PF08641.12 OAJ31768.1 - 1.8e-08 34.8 1.5 1.8e-08 34.8 1.5 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF3037 PF11236.8 OAJ31768.1 - 0.099 13.1 0.4 0.19 12.2 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Sec63 PF02889.16 OAJ31769.1 - 9.1e-149 493.6 0.0 8e-82 274.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 OAJ31769.1 - 1.5e-42 145.3 0.0 9e-25 87.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 OAJ31769.1 - 5.6e-37 126.3 0.2 1.7e-36 124.8 0.2 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 OAJ31769.1 - 5.6e-20 72.0 0.0 8.3e-15 55.2 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 OAJ31769.1 - 1.5e-11 44.7 0.0 1.2e-07 32.0 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 OAJ31769.1 - 1.9e-06 27.7 0.1 0.0053 16.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ31769.1 - 2.7e-05 24.4 0.1 0.019 15.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain PhoH PF02562.16 OAJ31769.1 - 0.071 12.6 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Actin PF00022.19 OAJ31770.1 - 1e-127 426.2 0.0 5e-127 423.9 0.0 1.8 1 1 0 1 1 1 1 Actin Rad21_Rec8 PF04824.16 OAJ31770.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein HEAT PF02985.22 OAJ31771.1 - 9.1e-05 22.4 6.5 0.72 10.3 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 OAJ31771.1 - 0.00031 21.1 0.5 0.029 14.8 0.1 5.1 5 1 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 OAJ31771.1 - 0.00044 20.3 1.8 0.0076 16.3 0.0 3.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Het-C PF07217.11 OAJ31771.1 - 0.075 11.6 0.1 0.18 10.3 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C HEAT_EZ PF13513.6 OAJ31771.1 - 0.29 11.7 4.2 73 4.0 0.0 4.9 4 0 0 4 4 4 0 HEAT-like repeat PHD PF00628.29 OAJ31772.1 - 8.2e-07 28.8 13.9 1.4e-06 28.0 13.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 OAJ31772.1 - 0.13 11.8 4.6 0.23 11.1 4.6 1.3 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 OAJ31772.1 - 0.38 10.8 3.7 0.81 9.8 3.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger SET PF00856.28 OAJ31772.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.4 3 2 0 3 3 3 0 SET domain Pkinase PF00069.25 OAJ31773.1 - 3.6e-67 226.5 0.0 7.5e-67 225.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31773.1 - 7.8e-50 169.6 0.0 1.3e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ31773.1 - 0.00013 20.9 0.0 0.00013 20.9 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 OAJ31773.1 - 0.029 13.3 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain TFIIA PF03153.13 OAJ31773.1 - 0.094 12.7 15.7 0.13 12.2 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 OAJ31773.1 - 0.27 10.5 1.9 0.85 8.9 0.0 2.6 4 0 0 4 4 4 0 Kinase-like SOG2 PF10428.9 OAJ31773.1 - 1.9 7.6 16.2 2.6 7.1 16.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein UQ_con PF00179.26 OAJ31774.1 - 3.2e-47 159.7 0.0 3.7e-47 159.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ31774.1 - 0.0021 17.8 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 OAJ31774.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 OAJ31774.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain IBN_N PF03810.19 OAJ31775.1 - 1.3e-05 25.0 0.0 6.6e-05 22.7 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 OAJ31775.1 - 0.07 13.4 2.6 21 5.7 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L38e PF01781.18 OAJ31776.1 - 5e-34 116.2 0.4 6.5e-34 115.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family zf-H2C2_2 PF13465.6 OAJ31777.1 - 3e-21 74.8 34.0 5e-06 26.7 0.7 6.6 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.26 OAJ31777.1 - 6.9e-18 64.0 49.6 0.00017 21.8 0.2 8.4 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ31777.1 - 4.9e-09 36.3 50.9 0.0063 17.3 0.9 8.5 9 0 0 9 9 7 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 OAJ31777.1 - 2.7e-06 27.2 16.3 0.002 18.1 0.6 5.2 4 0 0 4 4 4 2 C2H2-type zinc finger DUF2722 PF10846.8 OAJ31777.1 - 0.0013 17.8 1.6 0.0013 17.8 1.6 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 OAJ31777.1 - 0.0025 17.5 8.6 0.0084 15.8 8.6 1.9 1 0 0 1 1 1 1 Spt20 family zf-C2H2_jaz PF12171.8 OAJ31777.1 - 0.016 15.4 9.9 0.75 10.2 0.2 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 OAJ31777.1 - 0.021 15.5 0.7 0.021 15.5 0.7 7.1 4 1 3 7 7 6 0 FOXP coiled-coil domain zf_ZIC PF18366.1 OAJ31777.1 - 0.058 13.5 0.4 0.058 13.5 0.4 4.5 3 1 1 4 4 4 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 OAJ31777.1 - 0.066 13.4 7.4 5 7.2 1.2 3.2 1 1 1 3 3 3 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 OAJ31777.1 - 0.079 12.7 0.0 0.079 12.7 0.0 6.9 7 0 0 7 7 6 0 C2H2-type zinc-finger domain zf-C2H2_9 PF16293.5 OAJ31777.1 - 0.57 10.1 3.5 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) FYDLN_acid PF09538.10 OAJ31777.1 - 2.4 8.9 14.5 0.4 11.4 0.4 4.2 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) Ogr_Delta PF04606.12 OAJ31777.1 - 4.2 7.4 10.0 14 5.7 0.2 4.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_11 PF16622.5 OAJ31777.1 - 6.4 6.6 19.9 2.2 8.1 1.3 5.2 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-4CXXC_R1 PF10497.9 OAJ31778.1 - 0.0053 17.0 0.9 0.0063 16.7 0.9 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Poxvirus_B22R PF04395.12 OAJ31778.1 - 0.095 12.2 1.1 0.1 12.2 1.1 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein ABC1 PF03109.16 OAJ31779.1 - 5.1e-25 88.0 0.1 8.5e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 ABC1 family MBOAT PF03062.19 OAJ31780.1 - 2.7e-52 178.3 20.1 2.7e-52 178.3 20.1 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_S11 PF00411.19 OAJ31781.1 - 8.2e-45 151.7 0.9 1.3e-44 151.1 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 RFX_DNA_binding PF02257.15 OAJ31783.1 - 5.1e-22 78.3 0.2 9e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain RRM_1 PF00076.22 OAJ31784.1 - 4.1e-32 109.8 0.9 8.8e-20 70.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 OAJ31784.1 - 0.0011 18.9 0.0 0.5 10.5 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_Rrp7 PF17799.1 OAJ31784.1 - 0.0042 16.9 0.0 2.2 8.1 0.0 2.7 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 OAJ31784.1 - 0.016 15.3 0.1 1.7 8.8 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 OAJ31784.1 - 0.018 15.3 0.1 0.052 13.8 0.0 1.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 OAJ31784.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THOC2_N PF16134.5 OAJ31785.1 - 8e-114 381.6 3.0 1e-113 381.2 0.0 2.1 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 OAJ31785.1 - 1.9e-68 230.9 12.1 6e-67 226.0 0.6 3.4 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 OAJ31785.1 - 6.8e-24 83.7 0.1 1.6e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Rad1 PF02144.16 OAJ31786.1 - 1.3e-67 227.8 0.0 1.8e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OAJ31786.1 - 0.043 13.3 0.1 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Rad9 CsbD PF05532.12 OAJ31787.1 - 7.7e-05 22.5 20.6 0.0088 15.9 6.3 3.1 1 1 1 2 2 2 2 CsbD-like RIX1 PF08167.12 OAJ31789.1 - 1.7e-09 37.7 2.0 6.5e-08 32.5 0.2 2.9 2 0 0 2 2 2 2 rRNA processing/ribosome biogenesis DUF3025 PF11227.8 OAJ31789.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) MDD_C PF18376.1 OAJ31790.1 - 5.9e-69 231.6 0.0 7.7e-69 231.2 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 OAJ31790.1 - 5.7e-06 26.5 3.5 8.1e-06 26.0 1.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain NAP PF00956.18 OAJ31791.1 - 2.3e-95 318.8 4.9 2.3e-95 318.8 4.9 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.6 OAJ31791.1 - 5.5 7.3 20.7 3.2 8.0 1.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Drc1-Sld2 PF11719.8 OAJ31791.1 - 7.9 5.9 15.2 0.041 13.4 3.7 2.1 1 1 0 2 2 2 0 DNA replication and checkpoint protein Kelch_4 PF13418.6 OAJ31792.1 - 2.9e-23 81.6 0.6 6.8e-07 29.2 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.6 OAJ31792.1 - 5.4e-19 68.0 2.7 0.00054 20.2 0.1 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 OAJ31792.1 - 3.8e-12 45.6 0.1 1.1e-05 24.9 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 OAJ31792.1 - 1.9e-10 40.6 0.3 0.017 15.4 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 OAJ31792.1 - 3.6e-10 39.6 0.1 0.073 13.1 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 OAJ31792.1 - 5.5e-05 23.0 1.0 0.24 11.5 0.0 3.9 4 0 0 4 4 4 2 Kelch motif PQQ_3 PF13570.6 OAJ31792.1 - 0.025 15.0 0.1 0.18 12.3 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain G-alpha PF00503.20 OAJ31793.1 - 2e-107 359.4 0.1 2.3e-107 359.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 OAJ31793.1 - 3.4e-12 46.2 0.2 2.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 OAJ31793.1 - 0.022 14.1 0.1 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 OAJ31793.1 - 0.033 14.4 0.0 3.2 8.0 0.0 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 OAJ31793.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 OAJ31793.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 OAJ31793.1 - 0.061 12.7 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region CPT PF07931.12 OAJ31793.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 OAJ31793.1 - 0.13 12.3 0.0 19 5.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MCM PF00493.23 OAJ31793.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ThrE PF06738.12 OAJ31794.1 - 7.6e-51 172.8 24.4 2.5e-50 171.1 6.7 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 OAJ31794.1 - 3e-10 40.3 10.8 3e-10 40.3 10.8 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE MCM PF00493.23 OAJ31795.1 - 4.5e-97 323.5 0.0 6.2e-97 323.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 OAJ31795.1 - 1.5e-38 131.5 0.6 2.7e-38 130.6 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 OAJ31795.1 - 3e-27 94.9 1.5 3e-27 94.9 1.5 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 OAJ31795.1 - 8.6e-17 61.6 0.0 3.1e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 OAJ31795.1 - 3.8e-08 33.4 0.0 1e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ31795.1 - 4.5e-07 29.5 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ31795.1 - 9.5e-05 22.3 0.0 0.0018 18.1 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 OAJ31795.1 - 0.0098 15.6 0.0 0.59 9.8 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 OAJ31795.1 - 0.0099 16.3 0.1 0.07 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF3256 PF11644.8 OAJ31795.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) DUF3552 PF12072.8 OAJ31795.1 - 0.23 10.8 1.4 0.39 10.1 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSP90 PF00183.18 OAJ31796.1 - 1.5e-116 390.3 21.4 2e-116 389.9 21.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 OAJ31796.1 - 2.5e-15 56.9 0.0 4.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 OAJ31796.1 - 6.3e-10 39.0 0.1 6.3e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF45 PF01863.17 OAJ31796.1 - 0.74 9.8 8.1 1.3 9.0 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 RNase_PH PF01138.21 OAJ31797.1 - 3e-33 115.1 0.1 4.5e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 OAJ31797.1 - 0.024 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HSP90 PF00183.18 OAJ31798.1 - 3e-86 290.4 0.0 3.5e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 OAJ31798.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN HBS1_N PF08938.10 OAJ31798.1 - 0.04 14.2 0.4 0.04 14.2 0.4 1.8 2 0 0 2 2 2 0 HBS1 N-terminus Ubiq-assoc PF09145.10 OAJ31798.1 - 0.064 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-associated SUV3_C PF12513.8 OAJ31799.1 - 2.4e-15 56.2 0.4 5.2e-15 55.1 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 OAJ31799.1 - 8.6e-11 42.2 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRN3 PF05327.11 OAJ31799.1 - 0.47 8.9 3.2 0.87 8.0 3.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2834 PF11196.8 OAJ31800.1 - 0.26 11.7 8.9 3.8 7.9 0.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2834) YIF1 PF03878.15 OAJ31801.1 - 3.5e-90 301.7 0.0 4.5e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 OAJ31801.1 - 0.84 9.3 17.6 0.034 13.9 8.2 2.3 1 1 1 2 2 2 0 Yip1 domain Ribosomal_L11_N PF03946.14 OAJ31801.1 - 5 7.0 7.5 0.2 11.5 1.3 1.9 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain SKN1 PF03935.15 OAJ31802.1 - 4.3e-154 513.6 0.1 6.3e-154 513.1 0.1 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-C3HC4_2 PF13923.6 OAJ31803.1 - 2.5e-10 40.0 10.5 2.5e-10 40.0 10.5 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ31803.1 - 4.2e-09 36.1 6.1 4.2e-09 36.1 6.1 3.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 OAJ31803.1 - 6.8e-09 35.6 4.6 6.8e-09 35.6 4.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 OAJ31803.1 - 2.2e-08 34.3 9.3 2.2e-08 34.3 9.3 3.3 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ31803.1 - 1e-07 31.7 9.0 1e-07 31.7 9.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ31803.1 - 1.1e-06 28.5 6.1 1.1e-06 28.5 6.1 2.6 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 OAJ31803.1 - 2e-05 24.3 1.3 7.6e-05 22.5 1.3 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 OAJ31803.1 - 0.00039 20.2 8.7 0.00039 20.2 8.7 2.4 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 OAJ31803.1 - 0.00067 19.8 9.4 0.00067 19.8 9.4 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 OAJ31803.1 - 0.0014 18.8 7.0 0.0055 17.0 7.0 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 OAJ31803.1 - 0.0062 16.7 6.0 0.0062 16.7 6.0 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 U-box PF04564.15 OAJ31803.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 OAJ31803.1 - 0.27 11.1 3.2 0.61 9.9 3.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 OAJ31803.1 - 2.1 8.1 6.0 1.9 8.3 4.2 1.9 2 0 0 2 2 1 0 RING-like zinc finger zf-P11 PF03854.14 OAJ31803.1 - 2.8 7.7 10.8 1.1 9.0 6.2 2.6 2 1 1 3 3 3 0 P-11 zinc finger UQ_con PF00179.26 OAJ31804.1 - 3.7e-45 153.0 0.0 4.6e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 OAJ31804.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B HMG_box PF00505.19 OAJ31805.1 - 1.7e-20 73.2 0.7 1.7e-20 73.2 0.7 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 OAJ31805.1 - 1.7e-12 47.7 0.6 1.7e-12 47.7 0.6 1.8 1 1 1 2 2 2 1 HMG-box domain CHDNT PF08073.12 OAJ31805.1 - 0.057 13.4 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 OAJ31805.1 - 0.97 10.0 4.6 0.26 11.9 1.6 1.5 2 0 0 2 2 2 0 YABBY protein Mus7 PF09462.10 OAJ31806.1 - 2.7e-101 340.3 0.0 3.4e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Mus7/MMS22 family DIM PF08194.12 OAJ31807.1 - 0.36 11.1 1.7 0.54 10.5 1.7 1.3 1 0 0 1 1 1 0 DIM protein DUF3128 PF11326.8 OAJ31808.1 - 4e-18 65.5 1.3 7.1e-18 64.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DSPc PF00782.20 OAJ31808.1 - 8.8e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 OAJ31808.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Robl_LC7 PF03259.17 OAJ31810.1 - 5.5e-06 26.1 0.0 8.6e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Roadblock/LC7 domain SF1-HH PF16275.5 OAJ31812.1 - 1.1e-38 132.1 1.7 1.8e-38 131.4 1.7 1.3 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 OAJ31812.1 - 8.6e-10 38.2 14.4 8.3e-05 22.5 3.5 2.7 3 0 0 3 3 3 2 Zinc knuckle DUF1897 PF09005.10 OAJ31812.1 - 8.9e-09 34.7 15.5 0.00013 21.4 2.6 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF1897) KH_1 PF00013.29 OAJ31812.1 - 2.1e-08 33.9 0.1 3.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 OAJ31812.1 - 4.8e-07 29.6 10.3 0.00016 21.5 3.5 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 OAJ31812.1 - 0.33 10.8 14.9 0.45 10.4 5.1 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 OAJ31812.1 - 3.8 7.3 7.5 6.2 6.6 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.6 OAJ31812.1 - 6.6 7.6 6.9 14 6.6 6.9 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon adh_short_C2 PF13561.6 OAJ31813.1 - 2.7e-43 148.2 0.3 5.9e-43 147.1 0.3 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ31813.1 - 5.6e-43 146.7 0.1 8.6e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ31813.1 - 1e-08 35.3 2.1 3.3e-08 33.7 0.5 2.2 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 OAJ31813.1 - 7.2e-05 22.4 1.7 0.00064 19.3 1.7 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ31813.1 - 0.00033 20.2 0.7 0.0049 16.3 0.1 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 OAJ31813.1 - 0.016 14.5 0.4 0.029 13.7 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 OAJ31813.1 - 0.017 15.2 0.2 0.05 13.7 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 OAJ31813.1 - 0.021 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.15 OAJ31813.1 - 0.063 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 YjeF-related protein N-terminus MukF_M PF17192.4 OAJ31813.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 MukF middle domain NPR3 PF03666.13 OAJ31814.1 - 6.1e-81 272.6 0.1 7e-50 170.2 0.0 4.5 3 2 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 OAJ31814.1 - 0.0025 16.6 3.1 0.6 8.8 0.0 2.9 4 0 0 4 4 4 2 Nitrogen permease regulator 2 PTPLA PF04387.14 OAJ31815.1 - 4.5e-50 169.6 6.5 4.5e-50 169.6 6.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA FAD-oxidase_C PF02913.19 OAJ31817.1 - 3.5e-53 180.8 0.1 1.1e-52 179.2 0.1 1.7 1 1 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 OAJ31817.1 - 1.4e-25 89.7 0.0 7.9e-25 87.2 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 OAJ31817.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Acyl-thio_N PF12590.8 OAJ31818.1 - 0.029 15.0 1.4 0.029 15.0 1.4 1.7 2 0 0 2 2 2 0 Acyl-ATP thioesterase Apt1 PF10351.9 OAJ31818.1 - 0.2 10.5 5.7 0.23 10.3 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 OAJ31818.1 - 7.3 4.7 13.3 7.8 4.6 13.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NCA2 PF08637.10 OAJ31819.1 - 1.5e-75 254.0 0.0 3.2e-75 253.0 0.0 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Thioredoxin_13 PF18401.1 OAJ31819.1 - 0.1 12.5 0.3 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like domain Nrap_D4 PF17405.2 OAJ31820.1 - 1.6e-53 181.2 0.0 2.8e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 OAJ31820.1 - 2.5e-44 151.0 0.0 4.1e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 OAJ31820.1 - 7.4e-39 132.9 0.1 6.2e-38 129.9 0.0 2.4 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 OAJ31820.1 - 1.8e-37 128.9 0.0 3.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D5 PF17406.2 OAJ31820.1 - 1.7e-34 119.0 0.0 4.7e-34 117.5 0.0 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 OAJ31820.1 - 1.2e-26 93.5 0.0 3e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 6 BUD22 PF09073.10 OAJ31820.1 - 0.051 12.9 30.2 0.077 12.3 30.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 OAJ31820.1 - 0.28 10.6 25.0 0.5 9.7 25.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 OAJ31820.1 - 0.39 8.9 26.1 0.55 8.4 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L27A PF00828.19 OAJ31821.1 - 9.6e-35 120.1 0.0 1.4e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ATG101 PF07855.12 OAJ31822.1 - 9.6e-18 64.6 0.0 1.3e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 Autophagy-related protein 101 HU-HIG PF18291.1 OAJ31825.1 - 0.083 13.0 0.0 1.7 8.7 0.0 2.3 1 1 1 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif ABC_membrane PF00664.23 OAJ31826.1 - 3.4e-62 210.6 21.1 3.9e-38 131.7 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ31826.1 - 2.7e-50 170.4 0.0 5.5e-26 91.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 OAJ31826.1 - 2.8e-06 27.0 0.1 0.037 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 OAJ31826.1 - 3e-06 27.3 0.2 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 OAJ31826.1 - 8.3e-06 25.4 1.7 0.63 9.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 OAJ31826.1 - 0.00015 22.2 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 OAJ31826.1 - 0.00041 20.3 0.1 0.44 10.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 OAJ31826.1 - 0.00094 19.1 0.0 0.52 10.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 OAJ31826.1 - 0.00099 19.7 5.0 0.36 11.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 OAJ31826.1 - 0.0056 16.4 0.2 2.8 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 OAJ31826.1 - 0.0072 15.9 0.2 0.37 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 OAJ31826.1 - 0.012 14.9 1.0 0.24 10.7 0.2 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 OAJ31826.1 - 0.026 14.6 7.2 0.45 10.6 0.0 3.1 4 0 0 4 4 2 0 Dynamin family IstB_IS21 PF01695.17 OAJ31826.1 - 0.038 13.7 0.1 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 OAJ31826.1 - 0.051 13.3 3.8 1.7 8.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain ZZ PF00569.17 OAJ31827.1 - 1.9e-10 40.4 63.6 8.7e-06 25.5 2.1 6.7 6 1 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 OAJ31827.1 - 1.7e-05 24.7 0.1 3.7e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 OAJ31827.1 - 0.53 10.7 46.8 0.27 11.6 3.4 6.0 6 0 0 6 6 6 0 C1 domain dsDNA_bind PF01984.20 OAJ31828.1 - 1.3e-31 109.1 6.9 4e-31 107.6 6.9 1.7 1 1 0 1 1 1 1 Double-stranded DNA-binding domain Pkinase PF00069.25 OAJ31829.1 - 4.9e-69 232.6 0.0 8.5e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31829.1 - 1.6e-48 165.2 0.0 2.8e-48 164.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ31829.1 - 0.0002 20.8 0.0 0.0014 18.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 OAJ31829.1 - 0.0078 15.0 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RTTN_N PF14726.6 OAJ31829.1 - 0.11 13.4 1.0 1.1 10.1 0.1 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning PYRIN PF02758.16 OAJ31829.1 - 0.17 12.1 0.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Trp_DMAT PF11991.8 OAJ31830.1 - 2.9e-66 224.4 0.0 3.7e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Acetyltransf_17 PF17668.1 OAJ31830.1 - 0.012 16.4 0.1 0.057 14.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mei5_like PF17021.5 OAJ31830.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative double-strand recombination repair-like ThiF PF00899.21 OAJ31831.1 - 9.6e-25 87.3 0.0 2.7e-24 85.9 0.0 1.6 1 1 0 1 1 1 1 ThiF family 2-oxoacid_dh PF00198.23 OAJ31832.1 - 1.6e-77 260.1 0.1 2.1e-77 259.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 OAJ31832.1 - 3.9e-21 74.7 3.1 3.9e-21 74.7 3.1 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 OAJ31832.1 - 9.9e-16 57.8 0.1 3e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 OAJ31832.1 - 0.0094 15.8 1.3 4.5 7.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Endostatin PF06482.11 OAJ31832.1 - 0.058 12.9 0.5 0.1 12.1 0.5 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DNA_alkylation PF08713.11 OAJ31832.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA alkylation repair enzyme YqfD PF06898.11 OAJ31832.1 - 0.42 9.4 1.3 0.73 8.6 1.3 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD RNA_pol_Rpc4 PF05132.14 OAJ31832.1 - 0.65 10.4 9.5 0.23 11.9 5.9 2.1 1 1 1 2 2 2 0 RNA polymerase III RPC4 SspB PF04386.13 OAJ31832.1 - 0.65 9.9 5.8 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Stringent starvation protein B Roughex PF06020.11 OAJ31832.1 - 5.3 6.0 7.3 8.5 5.4 7.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 OAJ31832.1 - 7.4 4.6 4.9 9.3 4.2 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.9 OAJ31832.1 - 7.5 6.1 29.7 4.5 6.8 16.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PIG-S PF10510.9 OAJ31834.1 - 3.9e-109 365.8 0.1 5.4e-109 365.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myosin_head PF00063.21 OAJ31835.1 - 1.1e-260 866.6 0.6 1.8e-260 865.9 0.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 OAJ31835.1 - 1.8e-27 95.7 1.0 1.8e-27 95.7 1.0 3.4 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 OAJ31835.1 - 9.6e-06 25.0 33.8 0.6 10.1 0.4 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif CALCOCO1 PF07888.11 OAJ31835.1 - 0.0011 18.0 21.9 0.002 17.1 21.9 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Fib_alpha PF08702.10 OAJ31835.1 - 0.0012 19.0 5.5 0.0012 19.0 5.5 3.1 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family FlxA PF14282.6 OAJ31835.1 - 0.005 16.8 10.5 0.2 11.6 1.2 3.0 2 0 0 2 2 2 2 FlxA-like protein AAA_22 PF13401.6 OAJ31835.1 - 0.0052 17.1 0.4 0.024 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain DivIC PF04977.15 OAJ31835.1 - 0.0057 16.4 6.3 0.0057 16.4 6.3 3.1 2 1 1 3 3 3 1 Septum formation initiator Med9 PF07544.13 OAJ31835.1 - 0.02 15.0 13.9 0.035 14.2 3.2 3.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.6 OAJ31835.1 - 0.22 10.1 16.2 0.38 9.4 15.7 1.6 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 OAJ31835.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.4 3 1 0 3 3 2 0 AAA ATPase domain Phage_GPO PF05929.11 OAJ31835.1 - 1 8.9 11.5 2.5 7.7 11.5 1.7 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.11 OAJ31835.1 - 1.3 8.8 17.8 1 9.1 5.7 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 ATG16 PF08614.11 OAJ31835.1 - 1.4 9.1 29.0 1.1e+02 2.9 29.0 2.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 OAJ31835.1 - 1.9 7.3 29.4 56 2.4 29.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 OAJ31835.1 - 1.9 8.5 15.7 0.84 9.7 1.7 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 OAJ31835.1 - 2 8.5 31.7 0.76 9.8 11.3 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ABC_tran PF00005.27 OAJ31835.1 - 2.6 8.6 5.2 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter TolA_bind_tri PF16331.5 OAJ31835.1 - 4.4 7.4 18.8 0.023 14.8 2.6 3.6 3 0 0 3 3 3 0 TolA binding protein trimerisation His_kinase PF06580.13 OAJ31835.1 - 4.6 7.6 5.8 6 7.3 0.0 3.8 4 0 0 4 4 4 0 Histidine kinase Dynactin PF12455.8 OAJ31837.1 - 2.1e-52 178.1 1.4 2.1e-52 178.1 1.4 4.3 3 2 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.25 OAJ31837.1 - 9e-21 73.7 1.1 1.8e-20 72.7 1.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain TraI PF07057.11 OAJ31837.1 - 0.47 10.6 4.9 2.4 8.3 4.9 2.3 1 0 0 1 1 1 0 DNA helicase TraI Pyr_redox_2 PF07992.14 OAJ31840.1 - 2.7e-06 26.8 0.1 3.2e-05 23.3 0.2 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 OAJ31840.1 - 9.3e-05 21.8 0.1 0.079 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 OAJ31840.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 OAJ31840.1 - 0.0031 17.5 0.5 0.32 11.0 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 OAJ31840.1 - 0.013 14.6 0.3 0.024 13.8 0.3 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 OAJ31840.1 - 0.048 12.9 0.3 0.074 12.3 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 OAJ31840.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 OAJ31840.1 - 0.17 10.5 3.3 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein SNARE PF05739.19 OAJ31841.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.16 OAJ31841.1 - 0.0072 16.5 2.7 0.082 13.1 1.0 2.5 3 0 0 3 3 3 1 Flagellar FliJ protein YjcZ PF13990.6 OAJ31841.1 - 0.45 9.9 3.7 0.3 10.4 1.7 1.6 2 0 0 2 2 2 0 YjcZ-like protein SlyX PF04102.12 OAJ31841.1 - 2 9.1 10.6 0.67 10.6 2.3 3.7 3 2 1 4 4 4 0 SlyX Ribosomal_S18 PF01084.20 OAJ31842.1 - 3.5e-18 65.6 0.0 5.7e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 EMP24_GP25L PF01105.24 OAJ31843.1 - 7.4e-44 149.9 0.0 9.9e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Zn_clus PF00172.18 OAJ31844.1 - 8e-05 22.7 6.3 0.00013 22.0 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrome_C7 PF14522.6 OAJ31844.1 - 0.13 12.2 4.4 0.32 11.0 4.4 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c P34-Arc PF04045.14 OAJ31846.1 - 7.4e-108 359.8 1.0 9.8e-108 359.4 0.0 1.7 2 0 0 2 2 2 1 Arp2/3 complex, 34 kD subunit p34-Arc XRN_M PF17846.1 OAJ31846.1 - 3.3e-105 352.6 0.1 9.3e-105 351.1 0.1 1.6 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 OAJ31846.1 - 6.2e-84 281.2 0.0 1.3e-83 280.2 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 OAJ31846.1 - 1.7e-67 227.0 0.0 3.2e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 OAJ31846.1 - 1e-22 80.1 0.0 2.6e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 OAJ31846.1 - 5.8e-19 68.0 0.3 1.8e-18 66.4 0.1 2.0 2 0 0 2 2 2 1 Xrn1 SH3-like domain DNApol_Exo PF18136.1 OAJ31848.1 - 3.2e-81 272.6 0.1 7.7e-71 238.5 0.0 3.4 2 1 0 2 2 2 2 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 OAJ31848.1 - 1.2e-46 159.5 0.2 9e-46 156.6 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family A Glyco_hydro_3_C PF01915.22 OAJ31849.1 - 3.8e-50 170.7 0.0 7.7e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 OAJ31849.1 - 8e-39 133.9 0.0 1.4e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 OAJ31849.1 - 3.7e-19 68.6 0.0 8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1768 PF08719.11 OAJ31850.1 - 3.4e-22 79.4 0.0 5.4e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) UCH PF00443.29 OAJ31851.1 - 2.6e-38 132.0 0.0 3.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ31851.1 - 5.5e-08 32.8 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Herpes_BLRF2 PF05812.12 OAJ31851.1 - 0.003 17.7 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein Lambda_CIII PF02061.16 OAJ31852.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Lambda Phage CIII PARP PF00644.20 OAJ31853.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain HlyIII PF03006.20 OAJ31857.1 - 4.4e-57 193.4 21.4 9e-57 192.4 21.4 1.5 1 1 0 1 1 1 1 Haemolysin-III related UPF0060 PF02694.15 OAJ31857.1 - 0.077 13.2 3.3 0.076 13.2 0.9 2.2 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family YebO PF13974.6 OAJ31858.1 - 9.7 6.3 7.4 0.7 10.0 0.1 2.3 2 0 0 2 2 2 0 YebO-like protein SMC_N PF02463.19 OAJ31859.1 - 2.6e-69 233.0 0.0 4e-69 232.4 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ31859.1 - 6.8e-29 100.5 0.2 2.1e-28 99.0 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 OAJ31859.1 - 5.1e-18 66.3 14.8 5.1e-18 66.3 14.8 7.1 2 2 3 5 5 5 1 AAA domain AAA_15 PF13175.6 OAJ31859.1 - 1.7e-17 64.2 25.8 2e-13 50.8 7.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 OAJ31859.1 - 3.1e-13 50.2 7.6 1.4e-06 28.4 0.1 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system VWA_2 PF13519.6 OAJ31859.1 - 0.0022 18.6 4.3 0.0097 16.5 0.1 4.3 4 1 1 5 5 5 1 von Willebrand factor type A domain AAA_29 PF13555.6 OAJ31859.1 - 0.012 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 OAJ31859.1 - 0.12 11.8 0.0 0.12 11.8 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family ABC_tran PF00005.27 OAJ31859.1 - 0.23 12.0 19.9 0.65 10.5 0.0 5.2 3 2 0 4 4 4 0 ABC transporter HMA PF00403.26 OAJ31859.1 - 2 8.9 4.0 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 Heavy-metal-associated domain Tam41_Mmp37 PF09139.11 OAJ31861.1 - 3.2e-105 352.1 0.0 5.1e-105 351.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF4667 PF15700.5 OAJ31861.1 - 0.027 14.6 13.7 0.047 13.8 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SPX PF03105.19 OAJ31861.1 - 0.1 12.5 15.4 0.16 11.9 15.4 1.3 1 0 0 1 1 1 0 SPX domain Herpes_pp85 PF04637.12 OAJ31861.1 - 0.88 7.9 11.4 1.3 7.3 11.4 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FGGY_C PF02782.16 OAJ31863.1 - 1.3e-44 152.3 0.1 2e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 OAJ31863.1 - 2.2e-22 79.8 0.0 1e-21 77.6 0.0 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 OAJ31863.1 - 3e-05 23.6 0.2 8.4e-05 22.2 0.1 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 OAJ31863.1 - 0.00079 19.4 0.0 0.02 14.8 0.0 2.4 2 0 0 2 2 2 1 Hexokinase SNF2_N PF00176.23 OAJ31864.1 - 8.7e-61 205.6 0.0 1.5e-30 106.1 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 OAJ31864.1 - 3.9e-11 42.6 4.9 7.3e-11 41.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 OAJ31864.1 - 6e-11 42.7 0.0 6.1e-09 36.2 0.0 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 OAJ31864.1 - 4.7e-09 36.0 5.3 9.1e-09 35.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ31864.1 - 1e-07 32.1 4.9 2.1e-07 31.2 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 OAJ31864.1 - 1.1e-07 31.7 7.0 2.6e-07 30.5 7.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 OAJ31864.1 - 8.5e-07 28.7 2.6 1.6e-06 27.8 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ31864.1 - 4.7e-06 26.7 7.7 1e-05 25.6 7.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 OAJ31864.1 - 6.2e-05 22.8 3.8 0.00014 21.6 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 OAJ31864.1 - 9.6e-05 22.3 2.8 0.00021 21.2 2.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 OAJ31864.1 - 0.00054 20.2 2.7 0.0019 18.5 2.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 OAJ31864.1 - 0.058 13.3 2.4 0.13 12.1 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 OAJ31864.1 - 0.2 11.5 6.0 0.42 10.4 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 OAJ31864.1 - 0.27 11.4 2.5 0.68 10.1 2.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 RNase_PH PF01138.21 OAJ31865.1 - 4.5e-16 59.5 0.0 1e-15 58.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 QueF_N PF14819.6 OAJ31867.1 - 0.19 12.1 0.2 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term LEAP-2 PF07359.11 OAJ31868.1 - 0.089 12.6 0.3 0.089 12.6 0.3 5.1 5 0 0 5 5 5 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DUF3405 PF11885.8 OAJ31869.1 - 4.1e-81 273.1 7.2 5.8e-51 173.7 0.3 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3405) Aldo_ket_red PF00248.21 OAJ31870.1 - 1.2e-09 37.8 0.0 1.3e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Vezatin PF12632.7 OAJ31871.1 - 3.5e-10 39.7 0.0 2.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes FF PF01846.19 OAJ31872.1 - 1.4e-18 66.8 11.4 2.1e-08 34.2 0.1 5.1 6 1 0 6 6 6 2 FF domain WW PF00397.26 OAJ31872.1 - 8.2e-13 48.2 14.8 1.9e-06 27.8 2.2 2.6 2 0 0 2 2 2 2 WW domain DUF5338 PF17273.2 OAJ31872.1 - 0.0068 16.5 0.5 0.026 14.6 0.5 2.0 1 0 0 1 1 1 1 Family of unknown function (DUF5338) RhoGAP-FF1 PF16512.5 OAJ31872.1 - 0.02 15.5 0.3 0.02 15.5 0.3 3.0 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Sugar_tr PF00083.24 OAJ31873.1 - 8.9e-106 354.4 13.8 1.1e-105 354.2 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 OAJ31873.1 - 4.4e-28 98.2 23.1 1.2e-27 96.8 23.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 OAJ31873.1 - 0.035 12.5 2.8 0.047 12.1 0.4 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 OAJ31873.1 - 5.3 7.4 5.8 0.83 9.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Ribosomal_S11 PF00411.19 OAJ31874.1 - 2.4e-08 34.3 7.8 4.9e-08 33.3 0.7 3.1 3 1 0 3 3 3 1 Ribosomal protein S11 Amidohydro_1 PF01979.20 OAJ31875.1 - 4.5e-67 226.8 0.2 7.7e-67 226.0 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 OAJ31875.1 - 3.1e-58 195.4 0.6 9.9e-58 193.7 0.6 1.9 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 OAJ31875.1 - 2e-42 143.5 0.2 4.4e-42 142.4 0.2 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 OAJ31875.1 - 1.1e-35 121.5 0.0 2.9e-35 120.2 0.0 1.7 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 OAJ31875.1 - 1.1e-07 31.7 0.1 6.4e-07 29.2 0.0 2.2 2 1 0 2 2 2 1 Amidohydrolase family HlyD_D4 PF16572.5 OAJ31875.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB MT-A70 PF05063.14 OAJ31876.1 - 4.4e-37 127.6 0.3 9.3e-27 94.0 0.1 2.9 2 1 0 2 2 2 2 MT-A70 RRP36 PF06102.12 OAJ31877.1 - 1e-34 119.9 12.3 1e-34 119.9 12.3 3.6 3 1 0 3 3 3 2 rRNA biogenesis protein RRP36 Aldo_ket_red PF00248.21 OAJ31878.1 - 6e-26 91.3 0.0 5.9e-12 45.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family AAA PF00004.29 OAJ31879.1 - 2.2e-47 160.8 0.0 3.2e-43 147.3 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 OAJ31879.1 - 2.6e-20 72.6 0.0 5.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 OAJ31879.1 - 3.2e-14 52.4 3.3 6.4e-08 32.3 0.0 2.8 3 0 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 OAJ31879.1 - 2.5e-08 34.5 9.0 0.0033 17.8 0.6 4.5 2 2 2 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 OAJ31879.1 - 1.4e-05 25.7 0.0 0.28 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 OAJ31879.1 - 2.8e-05 24.3 0.0 0.046 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 OAJ31879.1 - 5.1e-05 23.6 4.9 0.41 10.9 0.2 4.5 4 2 1 5 5 3 2 AAA domain TsaE PF02367.17 OAJ31879.1 - 5.3e-05 23.2 0.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAJ31879.1 - 7.4e-05 22.8 0.1 0.49 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 OAJ31879.1 - 0.00025 21.0 0.2 3.9 7.4 0.0 4.2 4 0 0 4 4 4 1 NACHT domain RuvB_N PF05496.12 OAJ31879.1 - 0.00027 20.7 0.0 0.0034 17.1 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 OAJ31879.1 - 0.00033 20.3 3.6 2.5 7.6 0.4 4.5 3 2 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 OAJ31879.1 - 0.00062 19.2 0.2 0.94 8.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 OAJ31879.1 - 0.00068 20.0 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 OAJ31879.1 - 0.002 17.9 0.1 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF2075 PF09848.9 OAJ31879.1 - 0.0026 17.1 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 OAJ31879.1 - 0.0027 18.0 0.2 2.4 8.4 0.3 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 OAJ31879.1 - 0.0041 17.0 0.0 0.2 11.6 0.0 2.9 2 1 1 3 3 3 1 Adenylylsulphate kinase AAA_17 PF13207.6 OAJ31879.1 - 0.0058 17.0 0.1 0.48 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 OAJ31879.1 - 0.011 15.0 0.2 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_2 PF07724.14 OAJ31879.1 - 0.011 15.8 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 OAJ31879.1 - 0.016 14.9 0.0 0.063 13.0 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 OAJ31879.1 - 0.022 14.7 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 OAJ31879.1 - 0.028 13.8 0.3 4.2 6.6 0.1 2.4 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 OAJ31879.1 - 0.038 13.2 0.8 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 OAJ31879.1 - 0.054 13.2 0.0 4.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 OAJ31879.1 - 0.057 12.9 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 OAJ31879.1 - 0.061 13.7 0.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ31879.1 - 0.081 12.1 0.2 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 OAJ31879.1 - 0.11 12.6 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 OAJ31879.1 - 0.14 11.2 0.2 0.57 9.2 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 OAJ31879.1 - 0.15 11.8 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 OAJ31879.1 - 0.18 11.9 0.2 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 OAJ31879.1 - 0.31 10.8 1.7 2.3 8.0 1.5 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 OAJ31879.1 - 0.32 11.1 1.3 1.2 9.3 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase-like family Thiolase_N PF00108.23 OAJ31882.1 - 1.7e-79 266.8 9.1 1.8e-79 266.8 5.3 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ31882.1 - 1.3e-43 147.5 0.5 2.9e-43 146.4 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ31882.1 - 0.0095 15.5 4.4 0.022 14.4 0.4 3.1 3 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain DUF903 PF06004.12 OAJ31882.1 - 0.087 12.7 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) ACP_syn_III_C PF08541.10 OAJ31882.1 - 0.091 12.9 0.1 0.31 11.2 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Reprolysin_5 PF13688.6 OAJ31883.1 - 9e-45 153.2 5.1 9e-45 153.2 5.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 OAJ31883.1 - 2.1e-43 148.5 2.1 5.4e-43 147.2 2.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 OAJ31883.1 - 1.2e-42 145.9 1.1 3.3e-42 144.5 1.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 OAJ31883.1 - 2.1e-14 54.0 24.3 2.1e-14 54.0 24.3 4.0 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 OAJ31883.1 - 3.1e-11 43.9 0.0 7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 OAJ31883.1 - 2.6e-08 34.0 4.1 8e-07 29.2 0.1 3.4 2 1 0 3 3 3 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 OAJ31883.1 - 1.2e-06 28.8 0.1 2.7e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 OAJ31883.1 - 0.01 16.3 10.8 0.01 16.3 10.8 4.1 2 1 1 3 3 3 0 ADAM cysteine-rich domain TB2_DP1_HVA22 PF03134.19 OAJ31884.1 - 5.5e-07 29.4 0.2 2.4e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ank_4 PF13637.6 OAJ31886.1 - 1.4e-10 41.4 0.7 6.7e-06 26.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ31886.1 - 1.7e-06 28.5 0.0 4.1e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 OAJ31886.1 - 1.9e-05 24.6 0.1 0.00032 20.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 OAJ31886.1 - 3.2e-05 24.1 0.0 9.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 OAJ31886.1 - 0.0002 22.0 0.0 0.00044 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ31886.1 - 0.00058 20.5 0.0 0.0013 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ank PF00023.30 OAJ31886.1 - 0.0008 19.8 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Methyltransf_24 PF13578.6 OAJ31886.1 - 0.0031 18.5 0.0 0.016 16.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Dynactin_p22 PF07426.11 OAJ31887.1 - 6.3e-09 35.9 2.3 2.5e-07 30.7 0.3 2.8 2 1 0 2 2 2 2 Dynactin subunit p22 Pox_A_type_inc PF04508.12 OAJ31887.1 - 0.0016 18.2 1.1 0.87 9.5 0.2 2.6 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Lebercilin PF15619.6 OAJ31887.1 - 0.3 10.7 7.8 0.13 11.9 3.8 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Myb_DNA-binding PF00249.31 OAJ31888.1 - 9.8e-11 41.7 1.1 9.8e-11 41.7 1.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 OAJ31888.1 - 2.4e-07 30.9 2.0 3.7e-07 30.3 0.9 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 OAJ31888.1 - 0.049 13.5 0.3 0.09 12.7 0.3 1.4 1 0 0 1 1 1 0 Myb DNA-binding like SOCS PF12610.8 OAJ31888.1 - 0.19 12.2 5.0 0.099 13.0 0.9 2.9 2 0 0 2 2 2 0 Suppressor of cytokine signalling JAKMIP_CC3 PF16034.5 OAJ31888.1 - 4.5 7.2 8.2 3.1 7.7 3.9 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain CENP-T_C PF15511.6 OAJ31890.1 - 7.6e-08 32.5 0.1 9.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 OAJ31890.1 - 0.00021 21.4 0.1 0.00032 20.8 0.1 1.5 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 OAJ31890.1 - 0.00047 20.5 0.0 0.00062 20.1 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 OAJ31890.1 - 0.00062 20.1 0.1 0.0007 20.0 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 OAJ31890.1 - 0.00091 19.5 0.1 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 OAJ31890.1 - 0.05 13.7 0.0 0.056 13.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Syntaxin PF00804.25 OAJ31891.1 - 3e-26 92.3 8.6 3e-26 92.3 8.6 2.0 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 OAJ31891.1 - 7.3e-05 22.7 2.4 7.3e-05 22.7 2.4 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 OAJ31891.1 - 0.00016 21.9 4.4 0.00016 21.9 4.4 2.1 2 1 0 2 2 2 1 Syntaxin-like protein Muted PF14942.6 OAJ31891.1 - 0.0034 17.7 2.9 0.0034 17.7 2.9 2.2 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein Herpes_US9 PF06072.11 OAJ31891.1 - 0.079 12.8 2.2 0.18 11.7 2.2 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF1657 PF07870.11 OAJ31891.1 - 0.2 11.6 2.4 0.71 9.8 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1657) DUF2721 PF11026.8 OAJ31891.1 - 0.41 10.5 2.9 11 5.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) TcdA_TcdB PF12919.7 OAJ31891.1 - 1.1 8.5 9.5 0.4 9.9 4.1 2.1 1 1 1 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain TPR_14 PF13428.6 OAJ31891.1 - 2.1 9.4 5.1 3 8.9 0.1 3.5 4 1 0 4 4 3 0 Tetratricopeptide repeat GRP PF07172.11 OAJ31891.1 - 2.4 8.9 13.2 20 5.9 11.9 2.7 2 0 0 2 2 2 0 Glycine rich protein family Phage_Mu_Gam PF07352.12 OAJ31891.1 - 2.6 8.0 7.9 0.44 10.5 2.0 2.4 2 2 0 2 2 2 0 Bacteriophage Mu Gam like protein TMPIT PF07851.13 OAJ31891.1 - 2.7 7.1 8.5 1.2 8.3 1.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein dCache_1 PF02743.18 OAJ31891.1 - 3.1 7.5 6.9 1.4 8.7 3.9 1.7 1 1 0 2 2 2 0 Cache domain DUF4715 PF15835.5 OAJ31891.1 - 5.1 7.2 7.9 0.42 10.7 1.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4715) FUSC PF04632.12 OAJ31891.1 - 7.1 5.0 15.0 0.16 10.5 5.0 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family Ran_BP1 PF00638.18 OAJ31892.1 - 9.5e-15 54.9 0.0 2.4e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 RanBP1 domain Histone PF00125.24 OAJ31893.1 - 1.1e-49 168.1 3.9 1.3e-49 167.9 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 OAJ31893.1 - 9e-05 22.8 0.1 0.00014 22.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 OAJ31893.1 - 9.8e-05 23.0 0.8 0.0001 22.9 0.8 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 OAJ31893.1 - 0.00035 20.7 0.2 0.00035 20.7 0.2 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 OAJ31893.1 - 0.002 18.4 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HisKA PF00512.25 OAJ31893.1 - 0.035 14.1 0.3 0.064 13.3 0.3 1.4 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain F-box-like PF12937.7 OAJ31895.1 - 0.059 13.3 0.4 0.14 12.0 0.4 1.7 1 0 0 1 1 1 0 F-box-like AAA PF00004.29 OAJ31896.1 - 7.9e-52 175.2 0.0 9.6e-39 132.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 OAJ31896.1 - 3.8e-09 36.2 0.3 6.5e-08 32.3 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 OAJ31896.1 - 7.9e-09 35.2 0.0 2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 OAJ31896.1 - 3.8e-08 33.6 0.1 2.4e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 OAJ31896.1 - 2.4e-07 31.3 0.0 0.019 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 OAJ31896.1 - 4e-07 30.4 0.0 0.00014 22.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 OAJ31896.1 - 4.7e-07 29.7 0.1 0.023 14.4 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 OAJ31896.1 - 1.4e-06 27.8 0.1 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 OAJ31896.1 - 4.2e-06 27.3 0.0 0.033 14.7 0.0 3.1 2 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 OAJ31896.1 - 7.8e-06 25.9 0.0 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 OAJ31896.1 - 8.9e-06 25.2 0.3 0.0077 15.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 OAJ31896.1 - 1.3e-05 25.4 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 OAJ31896.1 - 7.7e-05 22.5 0.0 0.062 13.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 OAJ31896.1 - 0.00013 22.0 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 OAJ31896.1 - 0.00018 21.8 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 OAJ31896.1 - 0.00024 21.1 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 OAJ31896.1 - 0.0003 20.0 0.0 0.19 10.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 OAJ31896.1 - 0.00035 20.9 0.0 0.83 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 OAJ31896.1 - 0.00046 20.0 0.2 0.051 13.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 OAJ31896.1 - 0.0013 19.3 0.3 0.045 14.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 OAJ31896.1 - 0.0016 17.8 0.4 0.013 14.8 0.1 2.2 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 OAJ31896.1 - 0.0024 17.4 1.6 0.031 13.8 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region KTI12 PF08433.10 OAJ31896.1 - 0.0024 17.4 0.1 0.79 9.1 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Sigma54_activat PF00158.26 OAJ31896.1 - 0.0026 17.5 0.0 0.96 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 OAJ31896.1 - 0.0048 16.8 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 OAJ31896.1 - 0.0056 16.6 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 OAJ31896.1 - 0.007 16.3 1.1 4.4 7.2 0.0 3.3 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.6 OAJ31896.1 - 0.0083 15.7 0.1 2.9 7.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 OAJ31896.1 - 0.011 15.5 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 OAJ31896.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 OAJ31896.1 - 0.019 14.9 0.3 29 4.5 0.0 3.5 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 OAJ31896.1 - 0.022 15.0 0.0 0.11 12.7 0.0 2.2 3 0 0 3 3 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_30 PF13604.6 OAJ31896.1 - 0.027 14.2 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 OAJ31896.1 - 0.042 14.1 0.3 0.5 10.6 0.1 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain T2SSE PF00437.20 OAJ31896.1 - 0.06 12.4 0.1 4.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IPT PF01745.16 OAJ31896.1 - 0.098 12.0 0.4 2.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Isopentenyl transferase AAA_17 PF13207.6 OAJ31896.1 - 0.099 13.1 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 OAJ31896.1 - 0.1 11.8 0.2 9.1 5.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 OAJ31896.1 - 0.14 12.1 0.1 0.35 10.8 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ31896.1 - 0.27 11.6 2.3 1.4 9.2 0.1 2.7 3 0 0 3 3 2 0 AAA domain Homoserine_dh PF00742.19 OAJ31897.1 - 2.3e-46 157.9 0.0 3.6e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 OAJ31897.1 - 1.6e-16 61.0 0.1 3e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ANAPC4 PF12896.7 OAJ31899.1 - 1.6e-21 76.7 0.1 2.6e-21 76.1 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Nup_retrotrp_bd PF10599.9 OAJ31899.1 - 1.8 9.3 8.3 0.19 12.4 1.7 2.7 2 0 0 2 2 2 0 Retro-transposon transporting motif Mac PF12464.8 OAJ31900.1 - 5.9e-10 39.2 0.0 1.7e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 OAJ31900.1 - 1.9e-09 36.9 10.7 2.4e-07 30.2 7.2 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 OAJ31900.1 - 6.8e-07 28.9 8.7 2.7e-06 27.0 7.3 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase GMC_oxred_N PF00732.19 OAJ31902.1 - 8.3e-40 137.0 0.0 1.3e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ31902.1 - 4.6e-22 79.1 0.4 3.2e-20 73.1 0.4 3.0 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 OAJ31902.1 - 1.5e-08 34.1 1.2 3.7e-05 23.0 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 OAJ31902.1 - 2e-05 24.7 0.6 6.5e-05 23.1 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 OAJ31902.1 - 0.00034 20.0 0.1 0.00051 19.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 OAJ31902.1 - 0.00037 20.2 1.7 0.011 15.4 0.6 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ31902.1 - 0.0038 16.5 0.2 0.011 15.0 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ31902.1 - 0.014 14.8 1.0 0.021 14.2 1.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ31902.1 - 0.03 13.0 0.3 0.056 12.1 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 OAJ31902.1 - 0.042 13.1 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 OAJ31902.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 OAJ31902.1 - 0.18 10.9 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 OAJ31902.1 - 0.19 11.4 1.2 0.33 10.6 1.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ammonium_transp PF00909.21 OAJ31903.1 - 2.7e-104 349.1 29.3 3.4e-104 348.7 29.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family YCII PF03795.14 OAJ31904.1 - 0.0069 16.8 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 YCII-related domain Serglycin PF04360.12 OAJ31904.1 - 0.012 15.6 12.8 0.11 12.4 10.3 2.5 3 0 0 3 3 3 0 Serglycin ER_lumen_recept PF00810.18 OAJ31905.1 - 2e-49 168.2 3.9 2e-49 168.2 3.9 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 OAJ31905.1 - 0.0096 15.7 13.1 0.013 15.2 0.8 4.0 4 0 0 4 4 4 2 PQ loop repeat 40S_S4_C PF16121.5 OAJ31905.1 - 0.045 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus Mago_nashi PF02792.14 OAJ31906.1 - 8.5e-76 252.9 0.4 9.4e-76 252.7 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein NIF PF03031.18 OAJ31907.1 - 5.6e-51 172.4 0.0 2.4e-50 170.3 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 OAJ31907.1 - 0.13 11.0 1.1 0.15 10.7 1.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Baculo_PP31 PF05311.11 OAJ31907.1 - 1.1 8.7 5.4 1.5 8.3 5.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NPR3 PF03666.13 OAJ31907.1 - 1.2 7.9 9.0 1.5 7.5 9.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.13 OAJ31907.1 - 1.3 8.2 15.0 1.5 8.0 15.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PPP4R2 PF09184.11 OAJ31907.1 - 3.2 7.3 13.0 4.5 6.8 13.0 1.2 1 0 0 1 1 1 0 PPP4R2 Spem1 PF15670.5 OAJ31907.1 - 5.1 6.6 12.0 7.6 6.0 12.0 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 FAM60A PF15396.6 OAJ31907.1 - 5.4 7.0 8.3 8.8 6.3 8.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Afi1 PF07792.12 OAJ31907.1 - 6.3 7.3 11.7 11 6.5 11.7 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3449 PF11931.8 OAJ31908.1 - 4.3e-72 241.8 0.5 7.1e-71 237.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 OAJ31908.1 - 2.3e-23 82.5 0.6 5.9e-23 81.2 0.2 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 OAJ31908.1 - 6.3e-05 23.2 4.3 0.0015 18.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 OAJ31908.1 - 0.00056 19.7 0.1 0.0015 18.4 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_2 PF12756.7 OAJ31908.1 - 0.0034 17.7 0.4 3.9 7.9 0.2 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 OAJ31908.1 - 0.0049 17.1 7.0 0.014 15.7 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 OAJ31908.1 - 0.071 13.2 3.5 5.4 7.2 0.1 2.8 2 0 0 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.6 OAJ31908.1 - 0.15 13.0 3.0 8.9 7.5 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 OAJ31908.1 - 3.3 8.4 7.1 12 6.6 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2175 PF09943.9 OAJ31908.1 - 3.9 7.8 4.9 6.4 7.1 0.2 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) DEAD PF00270.29 OAJ31909.1 - 6.6e-44 149.8 0.5 1.1e-43 149.1 0.2 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ31909.1 - 3.1e-34 117.6 0.1 1.4e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ31909.1 - 0.00048 20.2 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 OAJ31909.1 - 0.0006 20.2 0.1 0.024 15.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ31909.1 - 0.0035 17.1 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain UTP25 PF06862.12 OAJ31909.1 - 0.044 12.6 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_RecD PF05127.14 OAJ31909.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 OAJ31909.1 - 0.073 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PX PF00787.24 OAJ31910.1 - 2.1e-11 43.8 0.0 4.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 PX domain SpoIIIAH PF12685.7 OAJ31910.1 - 0.27 11.0 1.1 0.8 9.5 0.5 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein Pinin_SDK_N PF04697.13 OAJ31910.1 - 2.3 8.8 7.1 0.15 12.7 0.3 2.7 3 0 0 3 3 3 0 pinin/SDK conserved region 4HBT PF03061.22 OAJ31911.1 - 1.8e-07 31.4 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily A_deaminase PF00962.22 OAJ31912.1 - 1.2e-118 396.2 0.1 1.9e-118 395.6 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase TFIIA PF03153.13 OAJ31912.1 - 0.26 11.2 15.7 0.42 10.6 15.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPT PF03151.16 OAJ31913.1 - 1.2e-45 156.2 13.7 2.3e-45 155.2 12.3 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 OAJ31913.1 - 2.2e-10 40.9 25.0 1.6e-06 28.3 11.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 OAJ31913.1 - 1.8e-06 27.4 12.7 3.3e-06 26.5 12.7 1.4 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 OAJ31913.1 - 0.022 15.4 4.9 0.022 15.4 4.9 2.2 2 0 0 2 2 2 0 Small Multidrug Resistance protein WD40 PF00400.32 OAJ31914.1 - 2.5e-43 145.2 23.5 6.3e-08 33.2 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ31914.1 - 3.8e-11 43.1 0.1 0.023 15.0 0.0 4.9 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 OAJ31914.1 - 6.8e-07 28.3 5.1 0.11 11.1 0.2 4.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 OAJ31914.1 - 0.0092 15.1 0.0 0.64 9.1 0.0 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF1513) Ge1_WD40 PF16529.5 OAJ31914.1 - 0.026 13.5 0.1 29 3.5 0.0 3.6 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 OAJ31914.1 - 0.098 11.2 0.0 3.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 OAJ31914.1 - 0.18 11.1 0.0 23 4.2 0.0 2.5 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 OAJ31914.1 - 0.44 10.5 7.9 22 5.1 0.0 5.3 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Isy1 PF06246.12 OAJ31916.1 - 2.8e-80 269.6 6.9 9.2e-79 264.6 6.9 2.0 1 1 0 1 1 1 1 Isy1-like splicing family ADPrib_exo_Tox PF03496.14 OAJ31916.1 - 0.12 11.7 0.4 1 8.7 0.4 2.1 1 1 0 1 1 1 0 ADP-ribosyltransferase exoenzyme MOZ_SAS PF01853.18 OAJ31918.1 - 4e-56 189.5 0.1 8.2e-56 188.5 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ31918.1 - 2.6e-13 49.3 5.7 8.9e-07 28.4 0.2 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain SUIM_assoc PF16619.5 OAJ31918.1 - 0.0037 17.3 3.8 0.011 15.8 3.8 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Acetyltransf_7 PF13508.7 OAJ31918.1 - 0.038 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5525 PF17663.1 OAJ31918.1 - 1.5 6.8 13.5 2 6.4 13.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Gemini_C4 PF01492.17 OAJ31918.1 - 1.5 8.7 3.8 0.65 9.9 0.9 1.8 2 0 0 2 2 2 0 Geminivirus C4 protein Ribosomal_L30 PF00327.20 OAJ31919.1 - 4.8e-09 36.0 0.1 6.7e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e CSN8_PSD8_EIF3K PF10075.9 OAJ31921.1 - 2.7e-26 92.3 0.0 5.9e-26 91.2 0.0 1.6 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Mak10 PF04112.13 OAJ31923.1 - 7.2e-46 155.8 0.0 1.4e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase AAA_11 PF13086.6 OAJ31924.1 - 7.5e-55 186.5 0.0 7.5e-55 186.5 0.0 3.9 4 1 0 4 4 3 1 AAA domain AAA_12 PF13087.6 OAJ31924.1 - 3.5e-49 167.1 0.0 9.2e-49 165.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 OAJ31924.1 - 3.2e-08 33.5 2.5 5.3e-05 23.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 OAJ31924.1 - 8.5e-06 26.2 0.1 0.0004 20.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain Viral_helicase1 PF01443.18 OAJ31924.1 - 0.00026 20.8 0.0 0.48 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 OAJ31924.1 - 0.0012 18.6 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_23 PF13476.6 OAJ31924.1 - 0.0013 19.2 4.0 0.28 11.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.21 OAJ31924.1 - 0.0017 17.9 0.3 1.4 8.3 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA PF00004.29 OAJ31924.1 - 0.0041 17.6 0.1 0.031 14.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 OAJ31924.1 - 0.0059 16.2 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 OAJ31924.1 - 0.0064 16.8 0.1 0.037 14.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 OAJ31924.1 - 0.012 16.0 0.0 0.049 14.0 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain UvrD_C PF13361.6 OAJ31924.1 - 0.068 12.5 1.0 1.6 8.0 0.0 3.0 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 OAJ31924.1 - 0.084 13.4 0.1 0.78 10.2 0.0 2.5 2 0 0 2 2 2 0 ABC transporter PIF1 PF05970.14 OAJ31924.1 - 0.1 11.7 0.0 0.36 10.0 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase DUF2981 PF11200.8 OAJ31924.1 - 7.9 6.1 6.2 18 4.9 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) MGC-24 PF05283.11 OAJ31925.1 - 0.97 9.9 10.8 2.4 8.6 10.8 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Synaptobrevin PF00957.21 OAJ31926.1 - 1.4e-32 111.3 1.8 1.6e-32 111.2 1.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF948 PF06103.11 OAJ31926.1 - 1.5 9.1 5.9 0.87 9.9 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Chitin_synth_1 PF01644.17 OAJ31927.1 - 1.9e-79 265.3 0.1 3.1e-79 264.6 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 OAJ31927.1 - 1.5e-28 98.5 0.1 3.3e-28 97.5 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Ion_trans_2 PF07885.16 OAJ31927.1 - 6.6e-28 96.5 26.7 7.7e-16 57.8 10.8 3.4 4 0 0 4 4 4 2 Ion channel Chitin_synth_2 PF03142.15 OAJ31927.1 - 6.7e-21 74.5 5.3 2.5e-19 69.3 0.0 2.2 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 OAJ31927.1 - 7.8e-07 29.2 0.3 7.8e-07 29.2 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Lig_chan PF00060.26 OAJ31927.1 - 0.13 12.1 7.1 2.9 7.7 1.6 2.8 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2207 PF09972.9 OAJ31927.1 - 0.39 9.4 0.0 0.39 9.4 0.0 3.5 3 2 0 3 3 3 0 Predicted membrane protein (DUF2207) NUDIX PF00293.28 OAJ31928.1 - 2e-25 89.4 0.0 2.8e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain FAM101 PF15068.6 OAJ31929.1 - 0.00091 19.2 1.5 0.0026 17.8 1.5 1.8 1 0 0 1 1 1 1 FAM101 family PDZ_5 PF17817.1 OAJ31929.1 - 0.075 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Cpn10 PF00166.21 OAJ31930.1 - 1.5e-26 92.2 0.0 1.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DEAD PF00270.29 OAJ31931.1 - 7.3e-45 152.9 0.1 1.3e-44 152.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ31931.1 - 6.5e-24 84.4 0.0 4.8e-23 81.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 OAJ31931.1 - 2.1e-18 66.3 0.3 2.1e-18 66.3 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 OAJ31931.1 - 0.0001 21.6 0.0 0.00018 20.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 OAJ31931.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 OAJ31932.1 - 1.4e-09 37.7 0.0 4.8e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ31932.1 - 0.006 16.2 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 OAJ31932.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) zf-AN1 PF01428.16 OAJ31933.1 - 1e-16 60.8 33.1 1.1e-08 35.1 10.1 2.5 3 0 0 3 3 3 2 AN1-like Zinc finger QWRF PF04484.12 OAJ31933.1 - 0.11 12.2 5.6 0.19 11.4 5.6 1.4 1 0 0 1 1 1 0 QWRF family Cpn60_TCP1 PF00118.24 OAJ31934.1 - 2.9e-85 286.8 7.6 5.3e-85 285.9 7.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RVT_2 PF07727.14 OAJ31936.1 - 1.6e-70 237.5 0.0 2.3e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ31936.1 - 6.8e-17 61.8 0.3 2e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ31936.1 - 3.6e-05 23.5 0.1 0.00011 22.0 0.1 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 OAJ31936.1 - 0.0018 18.0 2.3 0.011 15.5 0.7 2.8 2 1 0 2 2 2 1 Integrase core domain DUF4889 PF16230.5 OAJ31936.1 - 9.7 6.5 6.7 36 4.7 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4889) ASH PF15780.5 OAJ31938.1 - 6.5e-06 26.3 0.0 0.1 12.8 0.0 3.8 4 1 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 OAJ31938.1 - 0.017 15.2 0.0 31 4.8 0.0 3.6 4 0 0 4 4 4 0 Flagellar-associated PapD-like DUF1090 PF06476.12 OAJ31938.1 - 0.03 14.4 2.3 0.074 13.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Exo84_C PF16528.5 OAJ31939.1 - 2.2e-53 181.1 0.7 3.5e-53 180.5 0.7 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 OAJ31939.1 - 5.5e-16 58.4 0.4 1.7e-15 56.9 0.4 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 OAJ31939.1 - 8.6e-06 25.9 0.3 2.2e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 CEP19 PF14933.6 OAJ31939.1 - 2.2 8.6 6.3 0.49 10.7 1.5 2.3 2 1 1 3 3 3 0 CEP19-like protein CRAL_TRIO PF00650.20 OAJ31940.1 - 4.1e-30 104.6 0.0 5.5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 OAJ31940.1 - 3.9e-06 27.1 0.0 5.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ31940.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain zf-CCHC PF00098.23 OAJ31941.1 - 6.4e-05 22.8 1.2 0.00015 21.7 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 OAJ31941.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SSF PF00474.17 OAJ31943.1 - 1e-20 74.0 27.3 1.9e-20 73.1 27.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family T3SSipB PF16535.5 OAJ31945.1 - 0.039 14.4 0.2 0.039 14.4 0.2 2.9 3 0 0 3 3 3 0 Type III cell invasion protein SipB DUF726 PF05277.12 OAJ31946.1 - 5.6e-35 120.9 15.9 2.2e-26 92.6 10.0 3.6 2 2 0 2 2 2 2 Protein of unknown function (DUF726) Ser_hydrolase PF06821.13 OAJ31946.1 - 0.00056 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 OAJ31946.1 - 0.019 15.6 0.1 0.019 15.6 0.1 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family DUF900 PF05990.12 OAJ31946.1 - 0.019 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 OAJ31946.1 - 0.16 11.1 0.1 0.37 9.9 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 OAJ31947.1 - 2.5e-08 33.9 0.0 3e-06 27.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold CoA_transf_3 PF02515.17 OAJ31948.1 - 1.4e-125 419.3 0.0 1.7e-125 419.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Galactosyl_T PF01762.21 OAJ31949.1 - 1.9e-12 47.4 0.4 3.2e-07 30.4 0.0 3.2 1 1 1 3 3 3 3 Galactosyltransferase YTH PF04146.15 OAJ31950.1 - 2.6e-52 177.1 0.0 2.6e-52 177.1 0.0 3.6 2 2 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 OAJ31950.1 - 0.0033 17.2 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.24 OAJ31951.1 - 1.4e-18 66.8 0.0 8.2e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 OAJ31951.1 - 2.3e-15 56.5 0.0 4.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 OAJ31951.1 - 0.00012 22.3 0.0 0.12 12.7 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 OAJ31951.1 - 0.00071 20.0 0.0 0.0046 17.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 OAJ31951.1 - 0.0039 17.1 0.0 0.016 15.1 0.0 2.0 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE EF-hand_1 PF00036.32 OAJ31952.1 - 1.8e-25 86.5 7.6 2.5e-08 32.9 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 OAJ31952.1 - 4.2e-25 88.0 5.0 2.4e-15 56.7 1.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 OAJ31952.1 - 2.4e-21 73.8 4.0 1.5e-06 27.7 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 OAJ31952.1 - 2e-12 46.8 5.3 0.00034 20.4 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 OAJ31952.1 - 1.1e-10 40.5 11.6 0.00013 21.3 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 OAJ31952.1 - 7.6e-10 38.7 6.0 0.00097 19.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 OAJ31952.1 - 5.1e-06 26.7 0.9 0.00032 21.0 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 OAJ31952.1 - 0.023 15.0 2.5 1.5 9.1 0.2 3.0 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 OAJ31952.1 - 1 9.2 4.4 18 5.2 0.1 3.2 2 1 1 3 3 3 0 Caleosin related protein Use1 PF09753.9 OAJ31953.1 - 4.9e-09 36.3 0.0 6.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 ANXA2R PF15721.5 OAJ31953.1 - 0.038 14.5 2.6 0.063 13.8 2.6 1.3 1 0 0 1 1 1 0 Annexin-2 receptor E1_DerP2_DerF2 PF02221.15 OAJ31954.1 - 6.6e-27 94.6 0.0 8.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 ML domain RsfS PF02410.15 OAJ31955.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Ribosomal silencing factor during starvation Dynamin_M PF01031.20 OAJ31956.1 - 1.4e-12 47.5 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region SPT2 PF08243.11 OAJ31956.1 - 0.014 15.9 3.6 0.076 13.6 2.2 2.2 2 0 0 2 2 2 0 SPT2 chromatin protein DUF4058 PF13267.6 OAJ31956.1 - 0.075 12.4 0.6 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) HsbA PF12296.8 OAJ31957.1 - 4.1e-14 53.0 3.5 4.1e-14 53.0 3.5 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A CheZ PF04344.13 OAJ31957.1 - 0.012 15.6 0.2 0.015 15.3 0.2 1.3 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF2969 PF11184.8 OAJ31957.1 - 0.043 14.2 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) Dynamin_M PF01031.20 OAJ31958.1 - 0.049 12.8 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 Dynamin central region Dynamin_M PF01031.20 OAJ31959.1 - 1.6e-23 83.3 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 OAJ31959.1 - 1.8e-22 80.2 0.0 2.3e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Dynamin family DUF1729 PF08354.10 OAJ31960.1 - 2.4e-20 72.8 0.0 3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) zf-C2H2 PF00096.26 OAJ31961.1 - 1.2e-08 34.9 13.0 0.00093 19.5 2.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 OAJ31961.1 - 7.3e-08 32.5 17.0 0.00021 21.6 4.3 4.0 3 0 0 3 3 3 3 Zinc-finger double domain 14-3-3 PF00244.20 OAJ31962.1 - 1.7e-108 361.3 4.1 1.9e-108 361.1 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 OAJ31962.1 - 0.35 11.4 2.6 0.62 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HisKA PF00512.25 OAJ31962.1 - 0.74 9.9 2.7 1.5 8.9 0.2 2.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain RabGAP-TBC PF00566.18 OAJ31963.1 - 1.5e-48 165.3 0.0 2.3e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 OAJ31963.1 - 1.8e-06 27.8 0.0 4.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain NUDIX PF00293.28 OAJ31964.1 - 4.9e-07 29.8 0.0 9.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain LIM PF00412.22 OAJ31965.1 - 2.5e-19 69.2 18.1 4.6e-11 42.8 6.6 3.0 2 1 0 2 2 2 2 LIM domain zf-CSL PF05207.13 OAJ31965.1 - 2.6 7.8 7.5 4.7 7.0 0.9 2.5 2 0 0 2 2 2 0 CSL zinc finger RhoGAP PF00620.27 OAJ31966.1 - 2.1e-43 147.8 0.0 3.6e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PX PF00787.24 OAJ31966.1 - 3.9e-05 23.6 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PX domain PH PF00169.29 OAJ31966.1 - 5.3e-05 23.7 0.0 0.0012 19.4 0.0 2.5 1 1 0 1 1 1 1 PH domain Clat_adaptor_s PF01217.20 OAJ31967.1 - 7.3e-09 35.7 0.0 9.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4266 PF14086.6 OAJ31967.1 - 0.0085 17.0 3.8 0.68 10.9 0.4 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4266) DUF4337 PF14235.6 OAJ31967.1 - 0.16 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RRM_1 PF00076.22 OAJ31968.1 - 2.1e-71 235.7 0.0 2.5e-18 65.6 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ31968.1 - 3.2e-06 26.8 0.0 0.82 9.3 0.0 5.3 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ31968.1 - 5.7e-06 26.1 0.0 0.43 10.5 0.0 4.5 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 OAJ31968.1 - 0.00023 21.2 0.0 0.19 11.9 0.0 4.1 5 0 0 5 5 5 1 RNA recognition motif RRM_Rrp7 PF17799.1 OAJ31968.1 - 0.00043 20.1 0.4 30 4.4 0.0 5.4 4 2 2 6 6 6 0 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 OAJ31968.1 - 0.0096 16.2 0.7 14 5.9 0.0 5.2 5 2 2 7 7 7 1 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 OAJ31968.1 - 0.01 15.9 1.9 0.46 10.6 0.0 4.3 4 2 1 5 5 4 0 Limkain b1 SET_assoc PF11767.8 OAJ31968.1 - 0.026 14.1 0.0 29 4.4 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_2 PF04059.12 OAJ31968.1 - 0.027 14.7 0.0 7.6 6.8 0.0 3.5 3 0 0 3 3 3 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.6 OAJ31968.1 - 0.031 14.3 0.0 7.2 6.7 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif YtxH PF12732.7 OAJ31968.1 - 3.4 8.3 7.9 15 6.2 7.9 2.1 1 0 0 1 1 1 0 YtxH-like protein NMO PF03060.15 OAJ31970.1 - 1.1e-32 113.7 3.2 2.1e-19 70.1 0.4 3.8 2 2 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 OAJ31970.1 - 0.0022 17.1 0.5 0.0047 16.0 0.1 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 OAJ31970.1 - 0.14 11.1 0.0 0.53 9.2 0.0 1.8 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TFIIE-A_C PF11521.8 OAJ31970.1 - 0.44 10.9 5.0 1.8 8.9 0.8 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha ABC2_membrane PF01061.24 OAJ31971.1 - 7.7e-63 211.7 52.3 5.2e-32 111.0 19.7 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 OAJ31971.1 - 9.5e-37 126.6 0.0 1.3e-18 67.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 OAJ31971.1 - 7.7e-20 70.6 0.0 7.7e-20 70.6 0.0 3.8 4 0 0 4 4 4 1 CDR ABC transporter ABC_trans_N PF14510.6 OAJ31971.1 - 8.3e-10 39.2 0.3 2.9e-09 37.4 0.3 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 OAJ31971.1 - 2.4e-07 31.3 3.4 0.0027 18.1 0.6 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 OAJ31971.1 - 2.3e-05 24.1 0.4 0.00063 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 OAJ31971.1 - 5.9e-05 22.7 1.5 0.2 11.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 OAJ31971.1 - 0.00016 21.7 0.4 0.019 14.9 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 OAJ31971.1 - 0.00016 21.6 0.1 0.43 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ31971.1 - 0.0024 17.9 0.2 3.5 7.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 OAJ31971.1 - 0.0031 17.8 0.5 2.3 8.5 0.4 3.0 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 OAJ31971.1 - 0.017 15.0 0.3 4 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 OAJ31971.1 - 0.022 15.2 0.2 7.2 7.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 OAJ31971.1 - 0.066 13.8 0.3 0.47 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhnG PF06754.12 OAJ31971.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG TsaE PF02367.17 OAJ31971.1 - 0.22 11.5 1.3 3.9 7.5 0.2 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 OAJ31971.1 - 0.24 11.6 3.9 0.1 12.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 OAJ31971.1 - 0.84 9.3 9.3 2.3 7.9 0.9 3.6 4 1 0 4 4 4 0 AAA domain eIF-5a PF01287.20 OAJ31972.1 - 1.5e-29 101.9 1.3 2e-29 101.5 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PCMD PF13201.6 OAJ31972.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain EFP_N PF08207.12 OAJ31972.1 - 0.028 14.4 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Pil1 PF13805.6 OAJ31972.1 - 0.098 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 Adaptin_N PF01602.20 OAJ31973.1 - 8.4e-126 420.6 8.6 1e-125 420.3 8.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 OAJ31973.1 - 7.5e-41 138.9 0.0 2.7e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 OAJ31973.1 - 2.6e-16 59.9 0.0 7.9e-16 58.3 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain RasGEF_N_2 PF14663.6 OAJ31973.1 - 0.29 11.5 1.4 8 6.9 0.1 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 OAJ31973.1 - 3.9 8.0 7.6 1.3 9.4 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat Ribosomal_L5_C PF00673.21 OAJ31975.1 - 1.7e-15 56.9 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 OAJ31975.1 - 0.047 14.0 0.3 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L5 SAGA-Tad1 PF12767.7 OAJ31976.1 - 1.6e-44 152.4 0.0 5.6e-44 150.6 0.0 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TrbI PF03743.14 OAJ31976.1 - 0.028 14.3 2.8 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein EccE PF11203.8 OAJ31976.1 - 4.9 7.6 9.8 2.8 8.3 3.5 3.0 1 1 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE ZapB PF06005.12 OAJ31977.1 - 0.12 12.8 1.5 0.25 11.8 0.0 2.3 3 0 0 3 3 3 0 Cell division protein ZapB FRQ PF09421.10 OAJ31977.1 - 0.28 9.2 5.3 0.41 8.6 5.3 1.1 1 0 0 1 1 1 0 Frequency clock protein CHCH PF06747.13 OAJ31978.1 - 1.4e-06 28.3 5.5 2e-06 27.8 5.5 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 OAJ31978.1 - 0.0073 16.3 2.5 0.011 15.8 2.5 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 OAJ31978.1 - 0.036 14.4 5.1 0.3 11.4 5.0 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 OAJ31978.1 - 0.12 12.7 4.7 0.81 10.1 0.7 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.17 OAJ31978.1 - 0.13 12.5 1.0 0.19 12.0 1.0 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 OAJ31978.1 - 0.25 11.6 2.5 1.8 8.9 0.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 OAJ31978.1 - 0.37 10.8 5.1 1.1 9.3 5.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PhoD PF09423.10 OAJ31980.1 - 8.3e-37 127.0 0.1 1.6e-36 126.0 0.1 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase zf-RVT PF13966.6 OAJ31981.1 - 0.014 16.1 2.0 0.014 16.1 2.0 2.5 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase zf-HC5HC2H_2 PF13832.6 OAJ31982.1 - 1.5e-19 70.1 1.8 1.5e-19 70.1 1.8 4.6 4 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 OAJ31982.1 - 7.7e-16 58.1 1.7 7.7e-16 58.1 1.7 4.7 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.29 OAJ31982.1 - 1.9e-14 53.3 47.1 2.6e-09 36.8 5.9 5.4 6 0 0 6 6 6 3 PHD-finger BAH PF01426.18 OAJ31982.1 - 1.7e-09 37.6 0.0 4.7e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 BAH domain GATA PF00320.27 OAJ31982.1 - 1.9e-06 27.4 3.3 1.9e-06 27.4 3.3 4.3 4 0 0 4 4 4 1 GATA zinc finger PHD_2 PF13831.6 OAJ31982.1 - 0.00015 21.3 3.0 0.00015 21.3 3.0 5.7 6 0 0 6 6 6 2 PHD-finger Myb_DNA-bind_7 PF15963.5 OAJ31982.1 - 0.0037 17.1 0.3 0.011 15.6 0.3 1.8 1 0 0 1 1 1 1 Myb DNA-binding like ELM2 PF01448.24 OAJ31982.1 - 0.01 16.6 0.1 0.16 12.7 0.0 2.9 3 0 0 3 3 3 0 ELM2 domain TMP_2 PF06791.13 OAJ31982.1 - 3.6 7.2 8.7 1.7 8.3 1.1 2.5 2 0 0 2 2 2 0 Prophage tail length tape measure protein C1_1 PF00130.22 OAJ31982.1 - 8.8 6.3 31.8 0.21 11.5 1.4 4.7 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF498 PF04430.14 OAJ31983.1 - 1.1e-25 89.8 0.0 2e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Cyclin PF08613.11 OAJ31984.1 - 3.1e-10 40.7 0.0 6.8e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 OAJ31984.1 - 6.8e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Sel_put PF04328.13 OAJ31984.1 - 0.2 11.7 8.1 0.054 13.5 3.5 2.6 2 0 0 2 2 2 0 Selenoprotein, putative ANAPC4_WD40 PF12894.7 OAJ31985.1 - 9.4e-06 25.8 0.0 0.083 13.2 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ31985.1 - 0.00049 20.9 3.3 0.094 13.6 0.3 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.9 OAJ31985.1 - 0.057 13.4 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF1186 PF06685.11 OAJ31986.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) tRNA-synt_2b PF00587.25 OAJ31987.1 - 2.2e-35 122.2 0.0 3.6e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 OAJ31987.1 - 1.2e-17 64.1 3.2 1.2e-17 64.1 3.2 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 OAJ31987.1 - 0.045 13.7 2.0 0.096 12.7 2.0 1.5 1 0 0 1 1 1 0 FlxA-like protein zf-C2H2_11 PF16622.5 OAJ31988.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type Serglycin PF04360.12 OAJ31988.1 - 0.0096 15.9 2.8 0.018 15.0 2.8 1.4 1 0 0 1 1 1 1 Serglycin zf-C2H2 PF00096.26 OAJ31988.1 - 0.1 13.1 0.0 0.1 13.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 OAJ31988.1 - 0.13 13.1 7.3 3.7 8.6 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RVT_1 PF00078.27 OAJ31991.1 - 4.6e-11 42.7 0.0 1.1e-08 34.8 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 OAJ31991.1 - 0.00011 22.8 0.0 0.00029 21.4 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 OAJ31991.1 - 0.0035 17.6 0.0 0.019 15.3 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 OAJ31991.1 - 0.0051 17.4 0.1 0.014 15.9 0.1 1.8 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease SSP160 PF06933.11 OAJ31993.1 - 1.9 6.6 14.4 2.4 6.3 14.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_1 PF00561.20 OAJ31995.1 - 1.7e-15 57.4 0.1 9.3e-12 45.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 OAJ31995.1 - 6e-14 52.0 0.0 1.8e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Cep57_MT_bd PF06657.13 OAJ31996.1 - 1.3e-08 35.1 1.8 1.3e-08 35.1 1.8 3.4 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Vpu PF00558.19 OAJ31996.1 - 0.23 11.2 3.9 18 5.2 3.0 2.8 2 0 0 2 2 2 0 Vpu protein CTU2 PF10288.9 OAJ31996.1 - 0.36 11.1 1.4 2.6 8.3 1.4 2.6 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Pkinase PF00069.25 OAJ31997.1 - 6.5e-66 222.4 0.0 9.1e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ31997.1 - 4.4e-42 144.2 0.0 6.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 OAJ31997.1 - 6.6e-12 45.7 0.1 2.8e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 OAJ31997.1 - 2e-11 43.8 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 OAJ31997.1 - 4.1e-11 43.1 0.0 9.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.6 OAJ31997.1 - 1.6e-07 30.9 0.0 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Mpp10 PF04006.12 OAJ31997.1 - 0.05 12.0 1.7 0.082 11.4 1.7 1.2 1 0 0 1 1 1 0 Mpp10 protein SAM_4 PF18017.1 OAJ31997.1 - 0.062 13.3 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RA PF00788.23 OAJ31997.1 - 0.18 12.5 0.0 0.64 10.7 0.0 2.0 1 1 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PPP4R2 PF09184.11 OAJ31997.1 - 0.75 9.3 5.6 1.9 8.0 5.6 1.7 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 OAJ31997.1 - 3.7 6.8 8.8 6.6 6.0 8.8 1.3 1 0 0 1 1 1 0 NOA36 protein KDZ PF18758.1 OAJ31998.1 - 1.2e-53 182.0 0.0 2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 OAJ31998.1 - 3.3e-07 30.4 0.0 7.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 OAJ31998.1 - 6e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases COesterase PF00135.28 OAJ31999.1 - 6.5e-57 193.6 0.0 1.1e-56 192.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ31999.1 - 1e-11 45.1 0.2 1.1e-10 41.8 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 OAJ31999.1 - 0.016 14.9 0.6 0.033 13.8 0.6 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 OAJ31999.1 - 0.03 13.8 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 OAJ31999.1 - 0.095 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 OAJ31999.1 - 0.8 10.3 6.4 0.29 11.7 1.5 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family DcpS_C PF11969.8 OAJ32000.1 - 6e-09 36.4 1.1 0.00037 20.9 0.2 2.4 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 OAJ32000.1 - 1e-05 26.2 0.6 0.11 13.3 0.1 2.4 2 0 0 2 2 2 2 HIT domain zf-C2HE PF16278.5 OAJ32000.1 - 0.00022 21.6 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Dimer_Tnp_hAT PF05699.14 OAJ32001.1 - 1.2e-23 82.7 0.0 2.5e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 OAJ32001.1 - 1.8e-05 24.7 0.0 5.1e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF 659) PP_kinase_C PF13090.6 OAJ32001.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 RhoGEF PF00621.20 OAJ32002.1 - 2.6e-30 106.0 0.0 2.6e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain 3-HAO PF06052.12 OAJ32003.1 - 1.4e-58 196.8 0.0 1.6e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 OAJ32003.1 - 3.8e-07 29.7 0.1 5.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 OAJ32003.1 - 0.0078 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 OAJ32003.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 OAJ32003.1 - 0.057 13.6 0.0 0.089 13.0 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family RVT_1 PF00078.27 OAJ32004.1 - 7.1e-37 127.1 0.0 1.1e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 OAJ32004.1 - 5.7e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 RNase H Ribosomal_S10 PF00338.22 OAJ32005.1 - 9.7e-23 80.3 0.0 1.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DEAD PF00270.29 OAJ32006.1 - 5.7e-15 55.5 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ32006.1 - 0.00029 21.1 0.0 0.00084 19.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_9 PF00759.19 OAJ32007.1 - 2.5 7.5 14.1 3.7 6.9 14.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glycos_transf_1 PF00534.20 OAJ32008.1 - 1.5e-18 66.9 0.0 7.7e-13 48.3 0.0 3.3 3 0 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 OAJ32008.1 - 6.2e-09 36.1 0.7 5.1e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 OAJ32008.1 - 0.00011 22.6 2.7 0.00018 22.0 0.0 2.6 3 1 0 3 3 3 1 Glycosyl transferases group 1 ALG11_N PF15924.5 OAJ32008.1 - 0.0022 18.1 0.0 0.023 14.8 0.0 2.3 3 0 0 3 3 3 1 ALG11 mannosyltransferase N-terminus Glyco_trans_4_4 PF13579.6 OAJ32008.1 - 0.0074 16.7 0.3 0.0074 16.7 0.3 2.7 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Spem1 PF15670.5 OAJ32008.1 - 0.073 12.6 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 ApoLp-III PF07464.11 OAJ32008.1 - 0.097 12.8 8.1 0.032 14.3 4.8 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ADH_N_2 PF16884.5 OAJ32009.1 - 9.9e-34 115.5 0.0 2e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 OAJ32009.1 - 1.4e-18 67.1 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ32009.1 - 3.1e-08 34.8 0.0 1.4e-07 32.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 OAJ32009.1 - 0.006 16.1 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 OAJ32009.1 - 0.013 15.0 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ELFV_dehydrog PF00208.21 OAJ32009.1 - 0.018 14.8 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RRM_1 PF00076.22 OAJ32010.1 - 4.5e-09 36.0 0.0 7.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bin3 PF06859.12 OAJ32011.1 - 3.4e-17 63.0 0.0 1.5e-13 51.3 0.0 2.9 1 1 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 OAJ32011.1 - 0.00038 21.1 0.0 0.0011 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ32011.1 - 0.00093 19.0 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ32011.1 - 0.015 15.9 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ32011.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.8 OAJ32011.1 - 4.5 7.7 11.5 0.52 10.6 1.3 2.9 2 0 0 2 2 2 0 Early growth response N-terminal domain PI-PLC-X PF00388.19 OAJ32012.1 - 2.5e-46 156.9 0.0 3.9e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 OAJ32012.1 - 1.5e-36 125.2 0.0 3e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 OAJ32012.1 - 0.029 14.7 0.0 0.098 13.0 0.0 1.9 1 1 0 1 1 1 0 C2 domain F-box-like PF12937.7 OAJ32013.1 - 2e-05 24.4 0.2 4.3e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ32013.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box domain PI3K_1B_p101 PF10486.9 OAJ32013.1 - 0.1 10.4 1.8 0.17 9.6 1.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleo_P87 PF07267.11 OAJ32013.1 - 2.2 7.0 6.6 0.19 10.6 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Amino_oxidase PF01593.24 OAJ32014.1 - 3.4e-14 53.0 0.0 4.6e-12 46.0 0.0 3.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ32014.1 - 1.1e-11 44.8 0.1 2.2e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ32014.1 - 1.7e-08 34.0 0.4 1.3e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ32014.1 - 2.6e-07 30.6 0.0 8.9e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ32014.1 - 9.4e-05 21.7 1.2 0.00028 20.1 1.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ32014.1 - 0.0012 19.3 3.4 0.0021 18.6 1.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ32014.1 - 0.0019 17.0 0.2 0.0028 16.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ32014.1 - 0.0048 16.2 0.1 0.0084 15.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 OAJ32014.1 - 0.0058 15.9 1.0 0.01 15.1 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 OAJ32014.1 - 0.012 14.4 0.9 1.5 7.6 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 OAJ32014.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 OAJ32014.1 - 0.025 13.9 0.1 0.049 13.0 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ32014.1 - 0.038 13.1 0.2 0.068 12.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 OAJ32014.1 - 0.047 13.3 0.4 0.098 12.3 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 OAJ32014.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 OAJ32014.1 - 0.077 12.2 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Thi4 family F420_oxidored PF03807.17 OAJ32014.1 - 0.16 12.6 0.3 0.46 11.1 0.3 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 OAJ32014.1 - 0.17 12.4 0.2 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAJ32014.1 - 0.18 11.8 0.8 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 OAJ32014.1 - 0.27 10.3 3.5 0.24 10.4 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A DnaJ PF00226.31 OAJ32015.1 - 1.8e-09 37.6 1.5 3e-09 36.9 0.0 2.1 2 1 0 2 2 1 1 DnaJ domain Peptidase_C37 PF05416.12 OAJ32015.1 - 0.00059 18.5 8.0 0.0007 18.2 8.0 1.1 1 0 0 1 1 1 1 Southampton virus-type processing peptidase TFIIA PF03153.13 OAJ32015.1 - 0.05 13.6 24.7 0.058 13.4 24.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRP14 PF15459.6 OAJ32015.1 - 0.056 14.1 2.0 0.056 14.1 2.0 3.1 1 1 2 3 3 2 0 60S ribosome biogenesis protein Rrp14 SpoIIP PF07454.11 OAJ32015.1 - 0.13 11.8 9.9 0.16 11.4 9.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 OAJ32015.1 - 0.16 12.1 8.0 0.2 11.8 8.0 1.3 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 OAJ32015.1 - 0.17 11.0 8.6 0.2 10.8 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 OAJ32015.1 - 0.18 11.8 10.6 0.24 11.4 10.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALMT PF11744.8 OAJ32015.1 - 0.35 9.7 11.4 0.49 9.2 11.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 OAJ32015.1 - 0.6 8.4 2.2 0.57 8.5 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UCR_TM PF02921.14 OAJ32015.1 - 0.71 10.4 0.0 0.71 10.4 0.0 2.4 2 1 0 2 2 1 0 Ubiquinol cytochrome reductase transmembrane region MMR1 PF08505.10 OAJ32015.1 - 0.79 10.0 15.3 1 9.6 15.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.14 OAJ32015.1 - 0.9 7.8 21.3 1.1 7.4 21.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 OAJ32015.1 - 0.97 8.4 14.8 1.2 8.1 14.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 FAM60A PF15396.6 OAJ32015.1 - 1.1 9.2 14.3 1.5 8.8 14.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.11 OAJ32015.1 - 1.3 9.0 15.5 1.7 8.7 15.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3523 PF12037.8 OAJ32015.1 - 2.9 7.2 35.4 4.5 6.6 35.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF913 PF06025.12 OAJ32015.1 - 2.9 6.8 8.6 4.1 6.3 8.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2370 PF10176.9 OAJ32015.1 - 3 7.4 5.8 4 7.0 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4228 PF14009.6 OAJ32015.1 - 3.8 7.9 11.4 3.6 7.9 10.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF3492 PF11997.8 OAJ32015.1 - 3.9 7.1 8.4 5.9 6.5 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) VIR_N PF15912.5 OAJ32015.1 - 4.7 6.7 12.1 5.8 6.4 12.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF1980 PF09323.10 OAJ32015.1 - 5.4 6.9 6.3 8.3 6.3 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) LMBR1 PF04791.16 OAJ32015.1 - 7 5.4 6.1 7.8 5.3 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NPR3 PF03666.13 OAJ32015.1 - 9.2 4.9 20.1 11 4.7 20.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rad60-SLD PF11976.8 OAJ32017.1 - 2.1e-11 43.5 0.3 2.1e-11 43.5 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 OAJ32017.1 - 9.9e-06 25.2 0.6 9.9e-06 25.2 0.6 1.7 2 0 0 2 2 2 1 Ubiquitin family DnaJ PF00226.31 OAJ32018.1 - 7.1e-08 32.5 0.0 6.6e-07 29.4 0.0 2.5 1 1 1 2 2 2 1 DnaJ domain DUF4028 PF13220.6 OAJ32019.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) COesterase PF00135.28 OAJ32020.1 - 2.7e-83 280.6 0.0 3.3e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 OAJ32020.1 - 2e-06 27.8 0.4 0.0062 16.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold BshC PF10079.9 OAJ32022.1 - 0.019 13.8 0.6 0.024 13.4 0.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Rrn6 PF10214.9 OAJ32022.1 - 0.029 12.9 0.1 0.029 12.9 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Auts2 PF15336.6 OAJ32022.1 - 0.062 13.4 8.1 0.088 12.9 8.1 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein MCM_bind PF09739.9 OAJ32022.1 - 0.17 10.3 2.1 0.21 10.0 2.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Neur_chan_memb PF02932.16 OAJ32022.1 - 0.17 11.9 0.1 0.22 11.6 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 OAJ32022.1 - 0.23 11.2 0.3 0.27 10.9 0.3 1.2 1 0 0 1 1 1 0 Connexin MotA_ExbB PF01618.16 OAJ32022.1 - 0.26 11.1 1.1 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family CDC45 PF02724.14 OAJ32022.1 - 0.41 8.9 3.6 0.54 8.5 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 OAJ32022.1 - 0.44 9.2 1.4 0.57 8.9 1.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 OAJ32022.1 - 0.72 9.6 7.1 0.88 9.3 7.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tho2 PF11262.8 OAJ32022.1 - 1.1 8.4 4.6 1.4 8.0 4.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3043 PF11241.8 OAJ32022.1 - 3.7 7.6 10.1 5.5 7.0 10.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) NARP1 PF12569.8 OAJ32022.1 - 4.5 6.1 9.9 5.5 5.8 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S8 PF00082.22 OAJ32023.1 - 2.7e-30 105.7 2.0 4.3e-30 105.0 2.0 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 OAJ32023.1 - 2.6e-09 37.8 0.0 6.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 OAJ32023.1 - 7.3e-05 22.7 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 PA domain ASH PF15780.5 OAJ32023.1 - 0.11 12.8 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MFS_1 PF07690.16 OAJ32024.1 - 2.2e-26 92.6 63.5 5.6e-21 74.8 32.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ32024.1 - 7.8e-07 28.3 34.9 6.5e-05 22.0 11.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Spt5_N PF11942.8 OAJ32025.1 - 3.1 8.8 17.6 10 7.2 3.8 3.8 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Sulfatase PF00884.23 OAJ32026.1 - 6.2e-59 199.9 0.0 8.7e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 OAJ32026.1 - 0.0095 14.6 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 OAJ32026.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 OAJ32026.1 - 0.025 15.3 0.1 1.4 9.7 0.1 2.7 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.18 OAJ32026.1 - 0.061 12.7 0.0 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Metalloenzyme superfamily Metallophos PF00149.28 OAJ32027.1 - 2.4e-09 38.0 0.3 5.6e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ32027.1 - 0.00021 21.5 0.0 0.017 15.4 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain ABC_membrane_2 PF06472.15 OAJ32028.1 - 2.5e-93 312.4 4.6 3.4e-93 311.9 4.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 OAJ32028.1 - 1.7e-17 64.2 0.0 3.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 OAJ32028.1 - 0.0021 17.8 0.1 0.0071 16.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 OAJ32028.1 - 0.0076 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 OAJ32028.1 - 0.023 15.1 0.1 0.052 14.0 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ32028.1 - 0.024 15.0 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 OAJ32028.1 - 0.027 14.2 0.1 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ32028.1 - 0.029 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 OAJ32028.1 - 0.032 14.8 0.0 0.096 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 OAJ32028.1 - 0.037 14.5 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 OAJ32028.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 OAJ32028.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3584 PF12128.8 OAJ32028.1 - 0.26 8.8 0.0 0.42 8.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SNO PF01174.19 OAJ32029.1 - 8.4e-51 172.5 0.0 8.4e-40 136.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 OAJ32029.1 - 2e-08 34.0 0.0 2.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 OAJ32029.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 OAJ32029.1 - 0.037 13.8 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family adh_short PF00106.25 OAJ32030.1 - 1.7e-09 37.5 0.0 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ32030.1 - 4.8e-06 26.3 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Collagen PF01391.18 OAJ32031.1 - 0.034 13.9 1.3 0.055 13.2 1.3 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 OAJ32032.1 - 7.2e-36 123.8 12.1 1.1e-35 123.2 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tad_C PF09977.9 OAJ32032.1 - 1.5 10.1 6.5 4.6 8.5 4.7 2.4 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly DDE_1 PF03184.19 OAJ32034.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease SPRY PF00622.28 OAJ32035.1 - 7.7e-05 22.8 0.0 0.04 14.0 0.0 3.0 3 0 0 3 3 3 2 SPRY domain SUIM_assoc PF16619.5 OAJ32035.1 - 0.25 11.4 5.5 0.31 11.1 2.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Svf1_C PF17187.4 OAJ32036.1 - 5.8e-46 156.3 0.0 1.2e-45 155.3 0.0 1.6 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 OAJ32036.1 - 7.5e-40 136.7 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GCP_C_terminal PF04130.13 OAJ32037.1 - 5.2e-22 78.7 1.4 4.2e-13 49.4 0.0 3.3 3 1 0 3 3 3 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 OAJ32037.1 - 2.4e-16 60.2 0.1 1.4e-15 57.8 0.1 2.2 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal REC114-like PF15165.6 OAJ32037.1 - 3.4 7.4 8.5 6.6 6.4 8.5 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Activator_LAG-3 PF11498.8 OAJ32037.1 - 7.1 5.5 23.2 12 4.8 23.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UNC-93 PF05978.16 OAJ32038.1 - 1.3e-05 24.9 5.6 1.3e-05 24.9 5.6 2.7 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 OAJ32038.1 - 2.1e-05 23.6 26.9 4.1e-05 22.7 26.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily ComJ PF11033.8 OAJ32038.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Competence protein J (ComJ) CDH-cyt PF16010.5 OAJ32039.1 - 9.6e-11 41.7 2.0 4.6e-10 39.5 2.0 1.9 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 OAJ32039.1 - 0.0018 18.5 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 OAJ32039.1 - 0.095 12.9 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) CUE PF02845.16 OAJ32041.1 - 2.5e-12 46.3 0.1 4.2e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 CUE domain LIP PF03583.14 OAJ32042.1 - 2.1e-45 155.3 0.0 2.9e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 OAJ32042.1 - 0.041 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family eIF3g PF12353.8 OAJ32043.1 - 1.5e-41 141.7 0.5 2.9e-41 140.8 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 OAJ32043.1 - 2.6e-18 65.6 0.0 4.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 OAJ32044.1 - 5.2e-05 24.0 0.0 0.00049 20.9 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase II-binding domain. DUF4054 PF13262.6 OAJ32044.1 - 2.8 8.0 5.2 0.6 10.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Ribosomal_L17 PF01196.19 OAJ32045.1 - 1.2e-26 93.4 0.4 1.9e-25 89.6 0.0 2.7 2 0 0 2 2 2 1 Ribosomal protein L17 Ribosomal_L11_N PF03946.14 OAJ32045.1 - 6.4e-23 80.4 1.5 1.6e-22 79.1 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 OAJ32045.1 - 1.2e-20 73.8 0.7 3.7e-20 72.2 0.3 2.2 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Clat_adaptor_s PF01217.20 OAJ32046.1 - 1.8e-19 70.1 0.0 2.9e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Dendrin PF15498.6 OAJ32046.1 - 0.1 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Nup84_Nup100 PF04121.13 OAJ32047.1 - 2.4e-120 402.9 0.0 5.7e-120 401.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 FH2 PF02181.23 OAJ32047.1 - 0.13 11.4 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain ThiF PF00899.21 OAJ32048.1 - 1.1e-17 64.2 0.0 2.6e-17 63.0 0.0 1.5 1 1 0 1 1 1 1 ThiF family Sid-5 PF17204.3 OAJ32048.1 - 0.2 11.9 0.0 0.46 10.7 0.0 1.5 1 0 0 1 1 1 0 Sid-5 family ATG7_N PF16420.5 OAJ32049.1 - 4.7e-81 272.7 0.0 6.5e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 OAJ32049.1 - 4.9e-47 160.3 0.0 8.3e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 OAJ32049.1 - 0.094 12.8 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TFIIB PF00382.19 OAJ32050.1 - 6.6e-39 131.8 2.8 7.2e-22 77.2 0.9 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 OAJ32050.1 - 3e-12 45.8 1.6 5.3e-12 45.1 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 OAJ32050.1 - 0.011 15.8 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Cyclin, C-terminal domain RB_B PF01857.20 OAJ32050.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 OAJ32050.1 - 0.14 11.9 0.7 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain HARE-HTH PF05066.13 OAJ32050.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain adh_short PF00106.25 OAJ32051.1 - 5.3e-30 104.3 0.0 7.6e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ32051.1 - 2.5e-26 92.7 0.0 4e-22 78.9 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ32051.1 - 3.1e-05 24.0 2.5 0.018 14.9 0.4 3.0 2 1 0 2 2 2 2 KR domain ADH_N PF08240.12 OAJ32052.1 - 1.5e-19 69.9 3.0 2.7e-19 69.0 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 OAJ32052.1 - 6.8e-15 55.2 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 OAJ32052.1 - 0.00012 21.5 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 OAJ32052.1 - 0.00024 21.2 0.0 0.0036 17.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 OAJ32052.1 - 0.0038 16.5 0.2 0.0088 15.4 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 OAJ32052.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 OAJ32052.1 - 0.016 15.3 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 OAJ32052.1 - 0.026 13.9 0.6 0.046 13.1 0.6 1.3 1 0 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.22 OAJ32052.1 - 0.028 15.3 0.0 0.059 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold XdhC_C PF13478.6 OAJ32052.1 - 0.059 13.9 0.0 0.75 10.3 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain PP-binding PF00550.25 OAJ32053.1 - 4e-16 59.1 0.2 7.1e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 OAJ32053.1 - 6.4e-07 29.5 0.1 1e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier FlaC_arch PF05377.11 OAJ32053.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PRD PF00874.20 OAJ32053.1 - 0.22 11.8 0.3 0.37 11.1 0.3 1.3 1 0 0 1 1 1 0 PRD domain Oxidored_FMN PF00724.20 OAJ32054.1 - 2.5e-49 168.4 0.0 3.5e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DnaJ PF00226.31 OAJ32056.1 - 2.2e-16 59.7 0.1 4.5e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3245 PF11595.8 OAJ32056.1 - 0.092 13.2 0.3 0.092 13.2 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3245) MoCF_biosynth PF00994.24 OAJ32057.1 - 3.2e-51 172.8 0.4 4.3e-26 91.3 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 OAJ32057.1 - 7.4e-31 107.0 1.8 1.4e-30 106.1 1.8 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 OAJ32057.1 - 3.6e-15 55.9 0.1 1e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) Metallophos PF00149.28 OAJ32058.1 - 2e-14 54.6 0.4 2.9e-14 54.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rav1p_C PF12234.8 OAJ32060.1 - 1.8e-97 327.3 0.0 2.7e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Pro_CA PF00484.19 OAJ32061.1 - 3.1e-17 63.3 0.1 4.5e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase IPK PF03770.16 OAJ32063.1 - 3.8e-52 177.0 0.0 1.3e-51 175.3 0.0 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase TFIIA PF03153.13 OAJ32063.1 - 0.0008 19.5 23.0 0.0008 19.5 23.0 2.9 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 OAJ32063.1 - 0.055 14.0 6.4 0.28 11.8 6.4 2.2 1 0 0 1 1 1 0 TCP family transcription factor WD40 PF00400.32 OAJ32064.1 - 0.064 14.2 0.2 0.59 11.1 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat PTPlike_phytase PF14566.6 OAJ32064.1 - 0.36 10.9 0.6 0.69 10.0 0.6 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate F-box PF00646.33 OAJ32065.1 - 0.001 18.9 0.1 0.0028 17.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ32065.1 - 0.015 15.2 0.4 0.031 14.1 0.4 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 OAJ32066.1 - 9e-55 185.9 0.0 5.5e-52 176.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32066.1 - 1.7e-25 89.8 0.0 1.8e-24 86.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ32066.1 - 1.1e-07 31.5 0.0 2.6e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 OAJ32066.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ32066.1 - 0.045 12.8 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FAD_binding_2 PF00890.24 OAJ32068.1 - 8.9e-87 291.9 0.1 1e-86 291.7 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ32068.1 - 3.7e-08 33.5 0.5 1.7e-07 31.4 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ32068.1 - 5e-07 29.6 2.9 3e-06 27.1 2.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 OAJ32068.1 - 9.8e-07 28.3 0.1 7.4e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ32068.1 - 1.8e-06 27.4 0.1 5.2e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 OAJ32068.1 - 5.1e-06 27.0 0.9 0.00022 21.7 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 OAJ32068.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ32068.1 - 0.00012 20.9 0.1 0.00012 20.9 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 OAJ32068.1 - 0.00062 19.1 0.0 0.00062 19.1 0.0 1.9 3 0 0 3 3 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 OAJ32068.1 - 0.0015 17.7 0.6 0.0015 17.7 0.6 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 OAJ32068.1 - 0.0045 16.1 0.6 0.0081 15.2 0.6 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 OAJ32068.1 - 0.022 14.0 2.1 0.034 13.4 0.2 2.1 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ32068.1 - 0.024 13.9 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAJ32068.1 - 0.027 14.9 0.0 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 OAJ32068.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ32068.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 OAJ32068.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_S5 PF00333.20 OAJ32069.1 - 2.3e-17 62.7 3.0 3e-17 62.3 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ32069.1 - 3e-17 61.8 0.0 7.2e-17 60.6 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PRP1_N PF06424.12 OAJ32069.1 - 0.13 12.7 5.0 5.3 7.4 0.8 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Pex14_N PF04695.13 OAJ32069.1 - 0.4 11.3 6.5 0.77 10.4 6.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.9 OAJ32069.1 - 0.84 8.4 6.3 1 8.1 6.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 OAJ32069.1 - 1.3 8.9 8.2 1.7 8.5 8.2 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 OAJ32069.1 - 5.2 7.0 15.1 9.5 6.2 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CENP-H PF05837.12 OAJ32070.1 - 0.32 11.4 10.2 4.4 7.8 3.9 3.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PKcGMP_CC PF16808.5 OAJ32070.1 - 6.7 6.7 7.7 24 4.9 1.0 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Golgin_A5 PF09787.9 OAJ32070.1 - 7.3 6.0 23.0 0.052 13.0 11.4 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Rsa3 PF14615.6 OAJ32071.1 - 8.6e-07 28.4 0.0 1.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 F-box PF00646.33 OAJ32072.1 - 3.3e-08 33.2 0.0 7.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 OAJ32072.1 - 0.00052 19.8 0.0 0.00092 19.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 OAJ32072.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 F-box CENP-B_dimeris PF09026.10 OAJ32072.1 - 0.045 14.1 3.3 0.093 13.1 3.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAJ32072.1 - 1.2 8.9 5.2 1.8 8.2 5.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sacchrp_dh_NADP PF03435.18 OAJ32073.1 - 9.6e-07 29.1 0.5 6e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GoLoco PF02188.17 OAJ32074.1 - 0.53 9.9 3.9 6 6.5 0.4 3.2 3 0 0 3 3 3 0 GoLoco motif SRP14 PF02290.15 OAJ32075.1 - 4.2e-13 49.5 0.1 2.2e-12 47.2 0.0 2.1 1 1 1 2 2 2 1 Signal recognition particle 14kD protein EF-hand_5 PF13202.6 OAJ32075.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 EF hand Wzy_C PF04932.15 OAJ32076.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.6 2 1 0 2 2 2 0 O-Antigen ligase HECT_2 PF09814.9 OAJ32078.1 - 7.7e-18 64.5 0.0 8.7e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Bromo_TP PF07524.13 OAJ32079.1 - 0.0029 17.6 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated tRNA-synt_2 PF00152.20 OAJ32080.1 - 2.7e-66 223.8 0.0 9.7e-66 222.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ32080.1 - 8.2e-05 22.5 0.0 0.00036 20.5 0.0 2.0 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Thiolase_N PF00108.23 OAJ32081.1 - 6.1e-65 219.2 0.1 1.4e-64 218.0 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 OAJ32081.1 - 1.8e-44 150.3 0.3 4.3e-44 149.1 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 OAJ32081.1 - 2.9e-06 27.0 0.1 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain YTH PF04146.15 OAJ32082.1 - 5.4e-34 117.5 0.3 1.4e-33 116.2 0.0 1.9 2 0 0 2 2 2 1 YT521-B-like domain Mem_trans PF03547.18 OAJ32083.1 - 8.7e-37 126.4 6.0 1.1e-33 116.2 0.1 2.7 2 1 0 2 2 2 2 Membrane transport protein DUF2428 PF10350.9 OAJ32084.1 - 6.7e-48 163.3 0.3 6.7e-48 163.3 0.3 2.1 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 OAJ32084.1 - 0.0015 18.6 2.1 31 5.2 0.0 4.4 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 OAJ32084.1 - 0.004 17.5 1.1 0.042 14.2 0.4 3.3 2 1 0 2 2 2 1 HEAT repeats Nairo_nucleo PF02477.15 OAJ32084.1 - 0.078 11.8 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Nucleocapsid N protein dCMP_cyt_deam_1 PF00383.23 OAJ32085.1 - 1.4e-13 50.6 0.4 2.4e-13 49.8 0.4 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 OAJ32085.1 - 6.5e-11 42.6 4.6 5.4e-10 39.6 0.6 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 OAJ32085.1 - 0.00028 20.6 1.9 0.025 14.2 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Abhydrolase_2 PF02230.16 OAJ32086.1 - 4.8e-59 199.8 0.0 6.2e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 OAJ32086.1 - 8.5e-08 31.8 0.1 0.0011 18.2 0.1 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ32086.1 - 3.9e-07 30.9 0.1 4.4e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ32086.1 - 7e-06 25.9 0.0 2.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 OAJ32086.1 - 0.026 14.0 0.0 0.064 12.7 0.0 1.9 1 1 1 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 OAJ32086.1 - 0.046 13.4 0.0 0.24 11.0 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Cutinase PF01083.22 OAJ32086.1 - 0.05 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 OAJ32086.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.14 OAJ32087.1 - 4.2e-51 174.0 0.1 5.9e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 OAJ32087.1 - 0.11 11.7 0.1 1.1 8.5 0.1 2.1 1 1 0 1 1 1 0 Serine aminopeptidase, S33 EI24 PF07264.11 OAJ32090.1 - 0.00075 19.8 9.4 0.0013 19.0 9.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AbiEi_4 PF13338.6 OAJ32091.1 - 0.054 13.7 0.1 50 4.2 0.0 3.4 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin ABC_membrane PF00664.23 OAJ32092.1 - 5.7e-42 144.3 13.6 1.2e-27 97.3 7.4 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 OAJ32092.1 - 1.9e-37 128.9 0.0 1.8e-29 103.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 OAJ32092.1 - 1.6e-08 34.3 0.5 0.00053 19.5 0.0 3.4 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ32092.1 - 6.4e-07 30.1 0.2 0.029 14.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 OAJ32092.1 - 2e-06 27.4 0.6 0.095 12.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 OAJ32092.1 - 3.2e-05 24.2 0.7 0.009 16.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 OAJ32092.1 - 4.4e-05 23.9 0.7 0.1 12.9 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 OAJ32092.1 - 0.00037 20.4 0.0 0.093 12.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 OAJ32092.1 - 0.0021 17.2 0.1 0.3 10.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_15 PF13175.6 OAJ32092.1 - 0.0024 17.7 0.0 1.4 8.6 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 OAJ32092.1 - 0.0046 17.0 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 OAJ32092.1 - 0.0055 16.8 0.2 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 OAJ32092.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 OAJ32092.1 - 0.014 15.4 0.1 2 8.3 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_ATPase PF09818.9 OAJ32092.1 - 0.018 13.8 0.4 1.1 8.0 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 OAJ32092.1 - 0.022 14.9 0.0 8.4 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 OAJ32092.1 - 0.032 14.3 0.0 4.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 OAJ32092.1 - 0.066 12.9 0.6 0.27 10.9 0.1 2.2 2 1 0 2 2 1 0 AAA domain DUF5345 PF17280.2 OAJ32092.1 - 0.074 13.0 4.4 0.46 10.5 4.4 2.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) ATPase_2 PF01637.18 OAJ32092.1 - 0.086 12.7 0.0 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 OAJ32092.1 - 0.11 11.4 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Abhydrolase_6 PF12697.7 OAJ32093.1 - 4.4e-18 66.7 0.9 4.8e-18 66.6 0.0 1.5 2 0 0 2 2 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ32093.1 - 3.4e-13 49.9 0.1 9.1e-12 45.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ32093.1 - 3.6e-13 49.4 0.1 5.7e-13 48.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 OAJ32093.1 - 8.2e-08 32.3 0.0 2.6e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 OAJ32093.1 - 0.0019 18.3 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.16 OAJ32093.1 - 0.0025 17.4 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Chlorophyllase PF07224.11 OAJ32093.1 - 0.0038 16.3 0.0 0.0055 15.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Palm_thioest PF02089.15 OAJ32093.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 OAJ32093.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 OAJ32093.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 OAJ32093.1 - 0.062 12.2 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LCAT PF02450.15 OAJ32093.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PAF-AH_p_II PF03403.13 OAJ32093.1 - 0.082 11.4 0.0 3.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 OAJ32093.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3089 PF11288.8 OAJ32093.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RsgA_GTPase PF03193.16 OAJ32093.1 - 0.23 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase WD40 PF00400.32 OAJ32095.1 - 7.3e-35 118.4 28.0 2.1e-06 28.4 0.5 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ32095.1 - 2.8e-14 53.2 1.1 0.0038 17.5 0.0 6.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 OAJ32095.1 - 4.2e-10 39.3 0.2 9.3e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 OAJ32095.1 - 1.1e-07 30.9 7.0 3.2 6.3 0.1 6.0 5 1 1 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 OAJ32095.1 - 4.8e-07 29.4 0.1 0.00037 19.9 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 OAJ32095.1 - 0.00029 20.5 0.9 0.045 13.3 0.1 3.3 2 1 1 3 3 3 1 PQQ-like domain F-box PF00646.33 OAJ32095.1 - 0.00035 20.4 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 OAJ32095.1 - 0.00062 20.2 5.5 6.6 7.4 0.2 5.8 5 1 0 6 6 6 2 PQQ-like domain DUF5046 PF16465.5 OAJ32095.1 - 0.033 13.6 0.0 1.3 8.4 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF5046) PGAP1 PF07819.13 OAJ32096.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 OAJ32096.1 - 0.21 10.3 0.0 0.56 8.8 0.0 1.6 2 0 0 2 2 2 0 Ndr family FTHFS PF01268.19 OAJ32097.1 - 1.3e-239 796.0 0.0 3.8e-239 794.5 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 OAJ32097.1 - 9.8e-63 210.2 0.7 9.8e-63 210.2 0.7 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 OAJ32097.1 - 1.2e-31 109.4 0.0 3.3e-31 108.0 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.17 OAJ32097.1 - 0.21 11.5 0.1 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.12 OAJ32098.1 - 2.3 8.3 14.2 0.024 14.7 4.5 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein HIG_1_N PF04588.13 OAJ32099.1 - 1.1e-16 60.8 0.2 1.6e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3446 PF11928.8 OAJ32099.1 - 3.3 8.1 13.7 3.6 8.0 1.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain PCNA_N PF00705.18 OAJ32100.1 - 2.4e-50 169.5 2.6 7.9e-50 167.8 1.1 2.2 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 OAJ32100.1 - 4.3e-43 146.5 0.0 1.4e-22 80.2 0.2 2.5 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 OAJ32100.1 - 5.4e-07 29.0 0.3 2.1e-05 23.7 0.3 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 OAJ32100.1 - 0.00013 21.5 0.0 0.00044 19.8 0.0 1.8 1 1 0 1 1 1 1 Rad9 DUF3246 PF11596.8 OAJ32100.1 - 0.058 12.8 1.1 0.1 12.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) FmiP_Thoc5 PF09766.9 OAJ32100.1 - 0.066 12.5 0.1 0.097 11.9 0.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 LRS4 PF10422.9 OAJ32100.1 - 0.32 10.5 3.7 0.73 9.4 1.0 2.0 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Metallopep PF12044.8 OAJ32101.1 - 5.7e-85 285.5 0.0 1.8e-68 231.1 0.0 3.0 2 1 0 2 2 2 2 Putative peptidase family Jacalin PF01419.17 OAJ32101.1 - 1.8e-17 63.5 0.0 0.00047 20.1 0.0 5.0 5 0 0 5 5 5 4 Jacalin-like lectin domain Peptidase_M66 PF10462.9 OAJ32101.1 - 0.0029 16.6 0.1 0.0049 15.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 PARP PF00644.20 OAJ32103.1 - 6.4e-14 52.0 0.4 1.6e-09 37.7 0.0 2.9 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Fasciclin PF02469.22 OAJ32103.1 - 0.023 14.9 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain DNA_pol3_delta2 PF13177.6 OAJ32103.1 - 0.043 13.6 0.2 0.06 13.1 0.2 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit zf-HC5HC2H PF13771.6 OAJ32103.1 - 0.36 11.1 5.7 6.1 7.2 1.2 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C4pol PF14260.6 OAJ32103.1 - 0.6 10.6 4.6 2.2 8.8 0.5 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CNH PF00780.22 OAJ32104.1 - 6.3e-35 121.1 0.0 1.2e-34 120.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 OAJ32104.1 - 2.2e-21 76.9 0.2 3.7e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 OAJ32104.1 - 0.00054 20.0 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 OAJ32104.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain PARP PF00644.20 OAJ32105.1 - 2.1e-07 30.7 0.1 3.2e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 OAJ32106.1 - 6.6e-14 52.5 0.3 7.8e-14 52.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Phage_30_3 PF08010.11 OAJ32106.1 - 0.0018 18.1 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 HECW1_helix PF18436.1 OAJ32106.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Dfp1_Him1_M PF08630.10 OAJ32107.1 - 4e-33 114.3 0.0 8.3e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 OAJ32107.1 - 3.8e-20 71.7 0.7 8.7e-20 70.6 0.7 1.7 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 OAJ32107.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 OAJ32107.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SSF PF00474.17 OAJ32108.1 - 1.1e-20 74.0 20.1 1.8e-20 73.2 20.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Fungal_trans PF04082.18 OAJ32109.1 - 0.059 12.4 1.2 0.13 11.2 0.2 1.9 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ32109.1 - 0.064 13.4 3.5 0.11 12.7 3.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_2 PF13409.6 OAJ32110.1 - 1.4e-10 41.3 0.0 2.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 OAJ32110.1 - 2.2e-10 40.8 0.0 4.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 OAJ32110.1 - 2.6e-09 37.3 0.1 4.5e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 OAJ32110.1 - 1.3e-08 34.7 0.0 2.2e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 OAJ32110.1 - 1.4e-06 28.4 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 OAJ32110.1 - 4.1e-06 26.9 0.0 8.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 OAJ32110.1 - 7e-05 23.4 0.0 0.00026 21.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 OAJ32110.1 - 0.033 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin rve PF00665.26 OAJ32111.1 - 2.8e-12 46.9 0.0 3.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 OAJ32111.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 OAJ32112.1 - 2.6e-22 79.0 0.1 3.6e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 OAJ32112.1 - 4e-07 29.8 0.0 7.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 OAJ32112.1 - 0.035 14.2 2.1 0.095 12.8 2.1 1.8 1 0 0 1 1 1 0 Zinc knuckle DUF4219 PF13961.6 OAJ32112.1 - 0.04 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) RVP PF00077.20 OAJ32112.1 - 0.057 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 OAJ32112.1 - 5.2 7.0 7.4 1.2 9.0 3.8 1.9 2 0 0 2 2 2 0 Zinc knuckle Mre11_DNA_bind PF04152.14 OAJ32113.1 - 7.1e-43 146.8 5.4 7.1e-43 146.8 5.4 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 OAJ32113.1 - 3.1e-12 47.4 0.3 5.8e-12 46.5 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 OAJ32113.1 - 1.4e-06 28.6 0.2 3.9e-05 23.9 0.2 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF573 PF04504.14 OAJ32113.1 - 0.017 15.7 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 S-AdoMet_synt_C PF02773.16 OAJ32114.1 - 2.7e-67 225.0 0.3 7e-67 223.7 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 OAJ32114.1 - 2.8e-46 156.6 0.0 5.1e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 OAJ32114.1 - 3.2e-45 152.9 0.2 6.4e-45 151.9 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 OAJ32114.1 - 0.025 13.4 0.0 0.12 11.2 0.0 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Inhibitor_I9 PF05922.16 OAJ32115.1 - 8.9e-08 32.7 0.0 3.1e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 OAJ32115.1 - 0.054 13.3 0.1 0.077 12.8 0.1 1.3 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain Acyl-CoA_dh_1 PF00441.24 OAJ32116.1 - 2.5e-42 144.6 0.9 4.3e-42 143.8 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 OAJ32116.1 - 2.2e-33 115.3 0.0 4e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 OAJ32116.1 - 2.7e-27 94.8 0.0 4.9e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 OAJ32116.1 - 2.5e-16 60.2 0.3 4.2e-16 59.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.17 OAJ32117.1 - 9.1e-73 244.2 0.0 8.4e-72 241.1 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 OAJ32117.1 - 1.1e-45 154.7 0.1 3.9e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 OAJ32117.1 - 3.4e-35 120.4 0.0 7.1e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 OAJ32117.1 - 1.3e-13 50.6 2.1 2.6e-13 49.6 2.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 OAJ32117.1 - 5e-08 32.7 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 OAJ32117.1 - 1e-05 25.2 0.1 2.6e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 OAJ32117.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 OAJ32117.1 - 0.001 19.8 1.9 1.7 9.4 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.19 OAJ32117.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SMYLE_N PF18615.1 OAJ32117.1 - 0.23 11.0 1.9 0.32 10.5 1.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DHFR_1 PF00186.19 OAJ32118.1 - 1.2e-25 90.1 0.0 2.7e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 Dihydrofolate reductase SUIM_assoc PF16619.5 OAJ32118.1 - 4.8e-07 29.8 0.0 0.095 12.8 0.0 2.5 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 dsDNA_bind PF01984.20 OAJ32118.1 - 0.0063 16.8 3.5 0.25 11.7 0.1 2.2 2 0 0 2 2 2 2 Double-stranded DNA-binding domain Spc7 PF08317.11 OAJ32119.1 - 8.5e-15 54.4 9.4 1.4e-14 53.7 9.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 OAJ32119.1 - 8e-05 22.6 0.3 0.00017 21.6 0.3 1.5 1 0 0 1 1 1 1 Spc7_C2 Wbp11 PF09429.10 OAJ32119.1 - 0.29 11.6 5.4 0.2 12.1 2.5 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 KELK PF15796.5 OAJ32119.1 - 0.32 11.5 4.4 1.3 9.5 4.5 2.1 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4407 PF14362.6 OAJ32119.1 - 0.32 10.3 5.2 0.57 9.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Snf7 PF03357.21 OAJ32120.1 - 5.5e-32 110.7 14.7 9.3e-32 110.0 14.7 1.4 1 0 0 1 1 1 1 Snf7 TIP39 PF14980.6 OAJ32120.1 - 0.12 12.3 2.1 0.39 10.6 2.1 1.9 1 0 0 1 1 1 0 TIP39 peptide Brix PF04427.18 OAJ32121.1 - 1.6e-36 126.3 0.0 2.1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain YL1 PF05764.13 OAJ32121.1 - 0.00088 19.5 22.0 0.011 15.9 10.6 2.2 2 0 0 2 2 2 2 YL1 nuclear protein CDC45 PF02724.14 OAJ32121.1 - 0.053 11.8 17.4 0.017 13.4 7.1 2.1 2 0 0 2 2 2 0 CDC45-like protein PTPRCAP PF15713.5 OAJ32121.1 - 0.21 11.8 19.5 0.11 12.8 6.0 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 OAJ32121.1 - 0.48 10.3 12.2 0.73 9.7 2.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region XAP5 PF04921.14 OAJ32121.1 - 2.2 8.0 18.1 0.36 10.6 1.7 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator Sporozoite_P67 PF05642.11 OAJ32121.1 - 3 5.8 10.8 0.43 8.6 2.7 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CPSF100_C PF13299.6 OAJ32121.1 - 4 7.6 8.8 6.5 6.9 1.2 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 OAJ32121.1 - 7.1 5.5 7.4 5.1 6.0 0.9 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Spt5_N PF11942.8 OAJ32121.1 - 9.7 7.2 29.4 0.27 12.2 2.3 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Serinc PF03348.15 OAJ32122.1 - 8.3e-151 502.7 6.0 9.8e-151 502.5 6.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YqhR PF11085.8 OAJ32122.1 - 0.051 13.5 3.0 0.091 12.7 2.3 1.8 1 1 0 1 1 1 0 Conserved membrane protein YqhR Nop14 PF04147.12 OAJ32124.1 - 0.068 11.4 1.6 0.15 10.2 1.6 1.5 1 0 0 1 1 1 0 Nop14-like family NDK PF00334.19 OAJ32125.1 - 1.4e-53 180.5 0.0 1.7e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 OAJ32125.1 - 0.0083 16.6 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ LapA_dom PF06305.11 OAJ32127.1 - 0.079 12.8 0.3 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain p450 PF00067.22 OAJ32128.1 - 1.4e-67 228.4 0.0 4.8e-53 180.5 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 DUF2085 PF09858.9 OAJ32128.1 - 0.22 12.0 1.1 6.7 7.3 0.0 3.0 4 0 0 4 4 4 0 Predicted membrane protein (DUF2085) Ribosomal_L13 PF00572.18 OAJ32129.1 - 2e-10 41.0 0.5 1.5e-08 34.9 0.1 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 TMEM189_B_dmain PF10520.9 OAJ32129.1 - 0.15 12.2 0.2 0.22 11.7 0.2 1.2 1 0 0 1 1 1 0 B domain of TMEM189, localisation domain Ribosomal_L32e PF01655.18 OAJ32130.1 - 1.5e-46 157.2 1.0 1.8e-46 157.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1771 PF08590.10 OAJ32131.1 - 9.1e-21 74.0 9.3 2.4e-20 72.7 9.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 OAJ32131.1 - 2.9e-13 50.0 1.0 6.3e-13 48.9 0.4 1.9 2 0 0 2 2 2 1 Smr domain Spt20 PF12090.8 OAJ32131.1 - 2.1 7.9 7.1 3.1 7.4 7.1 1.4 1 0 0 1 1 1 0 Spt20 family RNB PF00773.19 OAJ32135.1 - 2.4e-50 171.7 0.0 4.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 RNB domain MARVEL PF01284.23 OAJ32137.1 - 8.2e-06 25.9 9.8 1.4e-05 25.2 9.8 1.4 1 1 0 1 1 1 1 Membrane-associating domain Zip PF02535.22 OAJ32137.1 - 0.0011 18.3 0.5 0.0016 17.8 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SLATT_4 PF18186.1 OAJ32137.1 - 0.11 12.2 0.6 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 MgtE PF01769.16 OAJ32137.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.2 2 1 0 2 2 2 0 Divalent cation transporter EI24 PF07264.11 OAJ32137.1 - 2.5 8.3 12.5 0.22 11.8 6.2 1.9 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Nup54 PF13874.6 OAJ32138.1 - 7.6e-25 87.6 2.8 4.7e-23 81.8 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 OAJ32138.1 - 0.0064 16.4 0.2 0.0064 16.4 0.2 2.3 2 0 0 2 2 2 1 Nup54 C-terminal interacting domain Nucleoporin_FG PF13634.6 OAJ32138.1 - 0.019 15.8 63.9 0.35 11.7 26.6 4.0 2 1 1 3 3 3 0 Nucleoporin FG repeat region Spt20 PF12090.8 OAJ32138.1 - 5.7 6.5 14.4 9.3 5.8 14.4 1.3 1 0 0 1 1 1 0 Spt20 family DUF1748 PF08520.10 OAJ32139.1 - 1.2e-19 70.0 0.0 1.4e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MmgE_PrpD PF03972.14 OAJ32140.1 - 9.4e-144 479.2 0.5 1.4e-143 478.6 0.5 1.2 1 0 0 1 1 1 1 MmgE/PrpD family 5_3_exonuc PF01367.20 OAJ32140.1 - 0.12 12.9 0.1 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold EF-hand_7 PF13499.6 OAJ32144.1 - 6.4e-08 32.9 0.1 1e-07 32.3 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 OAJ32144.1 - 6e-07 28.6 0.1 1.3e-05 24.3 0.0 2.7 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 OAJ32144.1 - 1.3e-06 27.9 0.2 1.6e-05 24.5 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 OAJ32144.1 - 0.003 17.0 0.3 0.01 15.3 0.0 2.1 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 OAJ32144.1 - 0.0096 15.8 0.2 0.062 13.2 0.0 2.0 2 1 1 3 3 3 2 EF-hand domain pair FAM60A PF15396.6 OAJ32145.1 - 3.1 7.8 11.2 6.9 6.6 11.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A GCIP PF13324.6 OAJ32146.1 - 0.00042 20.0 14.6 0.00042 20.0 14.6 2.9 2 1 1 3 3 3 1 Grap2 and cyclin-D-interacting CNDH2_C PF16858.5 OAJ32146.1 - 0.009 15.9 4.0 0.018 14.9 4.0 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SAPS PF04499.15 OAJ32146.1 - 5.8 5.6 5.7 8.8 5.0 5.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.14 OAJ32146.1 - 7.5 6.3 14.5 1.5 8.6 8.0 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GPI2 PF06432.11 OAJ32147.1 - 8.9e-73 245.2 0.0 1.1e-71 241.6 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase EcsB PF05975.12 OAJ32147.1 - 0.29 9.9 4.3 2.9 6.7 0.3 2.5 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB RRM_1 PF00076.22 OAJ32148.1 - 9.1e-17 60.7 0.0 1.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 OAJ32148.1 - 3e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif P19Arf_N PF07392.12 OAJ32148.1 - 0.27 11.7 1.2 0.87 10.1 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF4211 PF13926.6 OAJ32150.1 - 8.4e-05 22.7 0.3 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) OsmC PF02566.19 OAJ32151.1 - 7.2e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 OsmC-like protein AAA PF00004.29 OAJ32152.1 - 0.00043 20.7 0.2 0.0033 17.9 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 OAJ32152.1 - 0.039 14.4 0.3 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 OAJ32152.1 - 0.039 13.0 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_Ag35 PF03286.14 OAJ32152.1 - 0.17 11.7 0.5 0.36 10.6 0.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TIP49 PF06068.13 OAJ32152.1 - 0.26 10.5 0.0 0.39 9.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain S36_mt PF10937.8 OAJ32154.1 - 7.2e-08 34.0 7.2 3.6e-07 31.8 7.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Pkinase PF00069.25 OAJ32155.1 - 8.9e-07 28.5 0.0 5.8e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32155.1 - 0.0043 16.4 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Adenylsucc_synt PF00709.21 OAJ32157.1 - 1.1e-174 581.3 0.0 1.3e-174 581.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase RIBIOP_C PF04950.12 OAJ32158.1 - 1.7e-84 283.7 0.0 1.7e-84 283.7 0.0 1.8 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ32158.1 - 6.6e-32 109.5 0.0 1.8e-31 108.1 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 OAJ32158.1 - 2.6e-05 24.7 4.4 2.7e-05 24.6 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain GTP_EFTU PF00009.27 OAJ32158.1 - 8.1e-05 22.3 0.0 0.0043 16.6 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 OAJ32158.1 - 0.00011 22.5 0.0 0.00036 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ32158.1 - 0.00025 21.2 1.6 0.00077 19.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 OAJ32158.1 - 0.0014 18.4 0.1 0.0045 16.7 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 OAJ32158.1 - 0.0023 17.9 0.2 0.006 16.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 OAJ32158.1 - 0.0064 16.9 0.6 0.012 16.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 OAJ32158.1 - 0.011 15.8 0.1 0.05 13.7 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 OAJ32158.1 - 0.013 15.1 0.0 0.044 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 OAJ32158.1 - 0.032 14.6 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 OAJ32158.1 - 0.034 14.4 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 OAJ32158.1 - 0.036 14.6 1.4 0.073 13.6 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_18 PF13238.6 OAJ32158.1 - 0.054 14.0 0.4 0.28 11.7 0.0 2.5 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 OAJ32158.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 OAJ32158.1 - 0.071 13.0 0.5 0.8 9.6 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase NB-ARC PF00931.22 OAJ32158.1 - 0.098 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 OAJ32158.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 OAJ32158.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 OAJ32158.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF202 PF02656.15 OAJ32159.1 - 1.3e-21 76.8 0.2 1.3e-21 76.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MAPEG PF01124.18 OAJ32160.1 - 7e-26 90.7 0.6 8.1e-26 90.5 0.6 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M3 PF01432.20 OAJ32160.1 - 0.36 10.1 0.9 8.9 5.4 0.4 2.0 1 1 1 2 2 2 0 Peptidase family M3 MFS_1 PF07690.16 OAJ32161.1 - 5.3e-35 121.0 11.8 5.3e-35 121.0 11.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 OAJ32161.1 - 5.9e-08 32.0 1.8 5.9e-08 32.0 1.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 OAJ32161.1 - 0.0035 15.8 0.9 0.0059 15.1 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nuc_H_symport PF03825.16 OAJ32161.1 - 0.013 14.5 7.5 0.028 13.4 0.7 2.4 2 0 0 2 2 2 0 Nucleoside H+ symporter Asp PF00026.23 OAJ32162.1 - 1.7e-64 218.2 0.0 2.2e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ32162.1 - 2.3e-11 44.2 0.8 9.9e-09 35.7 0.4 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ32162.1 - 2.1e-05 25.1 0.6 0.013 16.1 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 OAJ32162.1 - 0.00016 22.1 0.2 0.014 16.0 0.0 2.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease adh_short PF00106.25 OAJ32163.1 - 1.7e-45 154.9 0.2 2.3e-45 154.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ32163.1 - 2.6e-31 109.0 0.1 3.6e-31 108.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ32163.1 - 6.6e-14 52.2 3.3 5e-13 49.4 3.2 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 OAJ32163.1 - 2.1e-06 27.4 0.2 1.6e-05 24.5 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 OAJ32163.1 - 5.6e-05 22.7 0.0 8.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 OAJ32163.1 - 0.00055 19.0 0.4 0.00082 18.5 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 OAJ32163.1 - 0.0024 17.0 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FAD_binding_3 PF01494.19 OAJ32163.1 - 0.013 14.8 0.2 0.021 14.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Urocanase PF01175.18 OAJ32163.1 - 0.036 13.7 0.3 0.058 13.0 0.1 1.4 1 1 0 1 1 1 0 Urocanase Rossmann-like domain NAD_binding_10 PF13460.6 OAJ32163.1 - 0.039 13.8 0.9 0.061 13.2 0.9 1.6 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 OAJ32163.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ada_Zn_binding PF02805.16 OAJ32164.1 - 1.9e-20 72.7 8.9 3.3e-20 71.9 8.9 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 OAJ32164.1 - 0.004 17.2 0.1 0.0084 16.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family ADIP PF11559.8 OAJ32165.1 - 2.2e-20 73.3 4.5 3.9e-20 72.5 4.5 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CCDC144C PF14915.6 OAJ32165.1 - 0.0049 16.0 8.1 0.0076 15.4 8.1 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF1664 PF07889.12 OAJ32165.1 - 0.17 12.0 2.8 0.33 11.0 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 OAJ32165.1 - 0.31 11.6 7.8 0.4 11.2 6.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region ERM PF00769.19 OAJ32165.1 - 7 6.4 14.7 13 5.5 14.7 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.6 OAJ32165.1 - 8.5 5.9 9.9 19 4.8 7.2 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HSF_DNA-bind PF00447.17 OAJ32166.1 - 1.3e-31 109.0 0.1 1.3e-31 109.0 0.1 2.5 2 0 0 2 2 2 1 HSF-type DNA-binding FA_desaturase PF00487.24 OAJ32167.1 - 1.2e-23 84.3 26.7 7.6e-23 81.6 26.7 2.0 1 1 0 1 1 1 1 Fatty acid desaturase Na_H_Exchanger PF00999.21 OAJ32169.1 - 3.2e-44 151.3 18.7 4.2e-44 150.9 18.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_3_3 PF16083.5 OAJ32169.1 - 0.087 13.0 0.2 0.087 13.0 0.2 3.3 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III TMEM238 PF15125.6 OAJ32169.1 - 7.6 6.8 13.6 0.32 11.2 1.3 3.3 3 0 0 3 3 3 0 TMEM238 protein family LsmAD PF06741.13 OAJ32170.1 - 6.4e-27 93.9 1.2 1.5e-26 92.8 1.2 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 OAJ32170.1 - 4.1e-12 46.1 0.0 7.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DIRP PF06584.13 OAJ32170.1 - 0.2 11.8 0.7 0.42 10.8 0.7 1.4 1 0 0 1 1 1 0 DIRP L31 PF09784.9 OAJ32171.1 - 5.2e-43 145.6 0.5 5.9e-43 145.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Glyco_hydro_18 PF00704.28 OAJ32172.1 - 1e-81 275.1 0.0 1.2e-81 274.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos PF00149.28 OAJ32174.1 - 1e-27 98.0 0.0 1.3e-26 94.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 OAJ32174.1 - 7.9e-18 64.5 0.0 1.8e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 OAJ32174.1 - 3.7e-14 51.8 0.9 3.2e-06 26.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32174.1 - 7e-09 35.1 3.3 0.003 17.6 0.0 4.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ32174.1 - 0.00052 20.2 0.1 0.14 12.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32174.1 - 0.0081 16.3 0.5 0.48 10.8 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 OAJ32174.1 - 0.011 14.9 0.0 0.35 10.0 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ32174.1 - 0.017 14.8 0.0 1.6 8.5 0.0 2.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 OAJ32174.1 - 0.088 13.7 0.2 13 6.9 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ32174.1 - 0.19 12.0 1.5 5.6 7.3 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat RAI1 PF08652.11 OAJ32175.1 - 2.4e-21 75.7 0.0 6.1e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease GATA PF00320.27 OAJ32176.1 - 4.9e-14 51.6 8.6 1.1e-13 50.5 8.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 OAJ32176.1 - 0.0079 15.7 1.6 0.015 14.8 1.6 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Auto_anti-p27 PF06677.12 OAJ32176.1 - 0.24 11.6 0.5 0.42 10.8 0.5 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Synaptobrevin PF00957.21 OAJ32177.1 - 1.6e-14 53.5 1.3 1.6e-14 53.5 1.3 1.8 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 OAJ32177.1 - 5.7e-11 42.3 0.0 1.5e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Syntaxin-6_N PF09177.11 OAJ32177.1 - 0.069 13.7 0.2 0.15 12.6 0.2 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Methyltransf_12 PF08242.12 OAJ32178.1 - 8.7e-07 29.6 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 OAJ32178.1 - 8.8e-06 26.3 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ32178.1 - 1.8e-05 25.3 0.0 3.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ32178.1 - 8.2e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain SH3BGR PF04908.15 OAJ32179.1 - 4.2e-16 58.9 0.0 5.4e-08 32.9 0.0 3.2 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 OAJ32179.1 - 0.5 10.6 1.5 33 4.8 0.0 3.6 4 0 0 4 4 4 0 Glutaredoxin Ysc84 PF04366.12 OAJ32180.1 - 2.3e-41 140.5 0.0 6.2e-41 139.1 0.0 1.8 1 0 0 1 1 1 1 Las17-binding protein actin regulator ANAPC_CDC26 PF10471.9 OAJ32180.1 - 1.9 9.4 13.4 0.7 10.8 1.5 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 ANAPC4_WD40 PF12894.7 OAJ32182.1 - 0.00081 19.6 0.0 0.42 10.9 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ32182.1 - 0.0022 18.8 0.1 0.34 11.9 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Ion_trans PF00520.31 OAJ32183.1 - 1.4e-127 424.0 86.6 1.1e-39 136.2 11.8 5.1 5 0 0 5 5 5 5 Ion transport protein EF-hand_1 PF00036.32 OAJ32183.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 OAJ32183.1 - 0.064 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain GPHH PF16905.5 OAJ32183.1 - 0.073 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated HSP70 PF00012.20 OAJ32184.1 - 6.4e-259 860.2 8.6 7.3e-259 860.0 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 OAJ32184.1 - 8e-16 57.8 0.5 1.6e-14 53.5 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 OAJ32184.1 - 0.0075 16.7 2.1 2.6 8.5 0.0 3.2 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 OAJ32184.1 - 0.015 14.6 0.2 0.038 13.3 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 OAJ32184.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain MutS_III PF05192.18 OAJ32184.1 - 0.3 11.3 3.3 10 6.3 1.6 2.3 2 0 0 2 2 2 0 MutS domain III SMN PF06003.12 OAJ32185.1 - 3.9 6.7 8.2 4.7 6.4 8.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Cupin_5 PF06172.11 OAJ32186.1 - 5.8e-30 104.3 0.0 3.8e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) Ribosomal_L6 PF00347.23 OAJ32187.1 - 2.2e-23 82.7 3.5 3.5e-11 43.6 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 CTD_bind PF04818.13 OAJ32188.1 - 0.011 16.6 0.0 0.024 15.4 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 OAJ32188.1 - 0.07 13.6 1.2 0.45 11.0 0.5 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 OAJ32188.1 - 3.8 7.2 11.1 3.7 7.2 5.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TB2_DP1_HVA22 PF03134.19 OAJ32190.1 - 4.3e-20 71.4 5.2 4.3e-20 71.4 5.2 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family CHD5 PF04420.14 OAJ32191.1 - 1e-47 161.9 0.0 1.2e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 CHD5-like protein Myosin_tail_1 PF01576.19 OAJ32191.1 - 0.074 10.9 0.1 0.094 10.5 0.1 1.0 1 0 0 1 1 1 0 Myosin tail zinc_ribbon_15 PF17032.5 OAJ32192.1 - 1.7e-05 25.4 0.3 2.7e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family FYVE_2 PF02318.16 OAJ32192.1 - 0.043 14.0 2.5 0.6 10.3 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger SIR2 PF02146.17 OAJ32193.1 - 4.3e-54 183.1 0.0 6.6e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family NepR PF18557.1 OAJ32193.1 - 0.27 10.9 1.1 0.62 9.8 1.1 1.6 1 0 0 1 1 1 0 Anti-sigma factor NepR F-box PF00646.33 OAJ32195.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 OAJ32195.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 OAJ32195.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like PorA PF11271.8 OAJ32196.1 - 0.049 12.9 2.6 0.06 12.6 2.6 1.1 1 0 0 1 1 1 0 Porin PorA Tir_receptor_C PF07489.11 OAJ32196.1 - 0.077 13.0 4.9 0.12 12.3 4.9 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Dppa2_A PF14049.6 OAJ32197.1 - 0.019 15.1 0.8 0.26 11.4 0.0 2.5 2 0 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates DUF4794 PF16042.5 OAJ32197.1 - 6 7.9 7.5 2.2 9.3 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4794) 4HBT_3 PF13622.6 OAJ32198.1 - 5.8e-56 190.5 0.0 1.1e-55 189.6 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 OAJ32198.1 - 1.2e-21 77.0 0.0 1.9e-18 66.6 0.0 2.9 2 1 0 2 2 2 2 Acyl-CoA thioesterase Dus PF01207.17 OAJ32199.1 - 1e-46 159.4 0.0 1.5e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Vps51 PF08700.11 OAJ32200.1 - 5.6e-22 77.6 0.1 1.3e-21 76.4 0.0 1.6 1 1 1 2 2 2 1 Vps51/Vps67 COG5 PF10392.9 OAJ32200.1 - 0.001 19.2 0.4 0.0014 18.8 0.4 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 OAJ32200.1 - 0.0023 16.7 0.5 0.0031 16.3 0.5 1.1 1 0 0 1 1 1 1 Dor1-like family SKA2 PF16740.5 OAJ32200.1 - 0.004 16.9 0.1 0.0069 16.2 0.1 1.4 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF1744 PF08490.12 OAJ32200.1 - 0.073 11.6 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Vps52 PF04129.12 OAJ32200.1 - 0.16 10.7 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family NPC1_N PF16414.5 OAJ32201.1 - 3.7e-63 213.3 5.8 3.7e-63 213.3 5.8 3.2 2 1 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 OAJ32201.1 - 1.3e-61 208.8 10.1 5.2e-38 130.7 0.3 3.1 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 OAJ32201.1 - 1.4e-45 154.8 6.5 3.7e-23 82.1 0.2 2.9 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 OAJ32201.1 - 0.0027 15.4 4.1 0.0039 14.9 4.1 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MFS_Mycoplasma PF07672.13 OAJ32201.1 - 0.04 13.2 0.3 0.14 11.4 0.3 1.8 1 0 0 1 1 1 0 Mycoplasma MFS transporter ArfGap PF01412.18 OAJ32202.1 - 5.6e-40 136.1 1.6 8.2e-40 135.5 1.6 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_S8 PF00082.22 OAJ32203.1 - 4e-31 108.4 8.7 7.7e-31 107.4 8.7 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 OAJ32203.1 - 7.5e-12 45.8 0.2 1.7e-11 44.6 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 BRE1 PF08647.11 OAJ32204.1 - 2.7e-19 69.0 10.6 2.7e-19 69.0 10.6 7.9 5 3 1 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 OAJ32204.1 - 1.3e-06 28.2 13.9 2.3e-06 27.4 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ32204.1 - 1.9e-06 27.6 9.8 3.7e-06 26.7 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 OAJ32204.1 - 1.2e-05 25.0 3.3 2.6e-05 24.0 3.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 OAJ32204.1 - 1.7e-05 24.7 7.1 3.3e-05 23.8 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 OAJ32204.1 - 2e-05 24.4 12.5 4e-05 23.5 12.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 OAJ32204.1 - 2.3e-05 24.1 11.6 4e-05 23.4 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ32204.1 - 0.00064 20.0 11.0 0.0011 19.3 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ribbon_3 PF13248.6 OAJ32204.1 - 0.00091 18.6 2.3 0.002 17.5 0.6 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Fez1 PF06818.15 OAJ32204.1 - 0.0015 19.0 14.9 0.0015 19.0 14.9 5.2 4 1 1 5 5 4 3 Fez1 ATG16 PF08614.11 OAJ32204.1 - 0.0062 16.8 7.5 0.0062 16.8 7.5 7.4 5 2 2 7 7 7 3 Autophagy protein 16 (ATG16) zf-rbx1 PF12678.7 OAJ32204.1 - 0.0073 16.6 6.8 0.015 15.6 6.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 OAJ32204.1 - 0.0078 16.1 8.8 0.014 15.3 8.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PolyA_pol PF01743.20 OAJ32204.1 - 0.016 15.7 1.0 0.016 15.7 1.0 3.7 4 1 0 4 4 4 0 Poly A polymerase head domain Seryl_tRNA_N PF02403.22 OAJ32204.1 - 0.016 15.4 4.7 0.016 15.4 4.7 8.3 4 3 2 8 8 8 0 Seryl-tRNA synthetase N-terminal domain CM_2 PF01817.21 OAJ32204.1 - 0.036 14.4 4.8 0.06 13.7 0.1 3.8 3 0 0 3 3 2 0 Chorismate mutase type II zf-C3HC4_4 PF15227.6 OAJ32204.1 - 0.085 13.0 10.5 0.056 13.6 8.7 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 OAJ32204.1 - 0.14 12.2 4.5 0.35 11.0 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 OAJ32204.1 - 0.54 10.3 6.8 1.1 9.3 6.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 OAJ32204.1 - 0.77 9.6 4.6 1.7 8.6 4.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FlaC_arch PF05377.11 OAJ32204.1 - 2.6 8.5 21.1 1.6 9.2 0.8 6.7 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) zf-C3HC4_5 PF17121.5 OAJ32204.1 - 3.9 7.4 5.3 8.8 6.3 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Per1 PF04080.13 OAJ32205.1 - 1.5e-91 306.7 0.2 2.1e-91 306.2 0.2 1.2 1 0 0 1 1 1 1 Per1-like family Arf PF00025.21 OAJ32206.1 - 3e-67 225.4 0.1 3.6e-67 225.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ32206.1 - 1.8e-12 47.1 1.5 6.4e-07 28.9 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 OAJ32206.1 - 1.1e-11 44.9 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ32206.1 - 3.3e-09 36.4 0.0 4.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 OAJ32206.1 - 9.4e-08 31.7 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 OAJ32206.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAJ32206.1 - 5.8e-06 26.4 0.0 8.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 OAJ32206.1 - 0.013 15.0 0.0 0.14 11.7 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 OAJ32206.1 - 0.047 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 OAJ32206.1 - 0.076 12.5 0.1 0.24 10.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 OAJ32206.1 - 0.22 11.2 0.3 0.28 10.8 0.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain FTR1 PF03239.14 OAJ32207.1 - 1.8e-54 185.0 4.9 1.8e-34 119.3 2.9 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family Herpes_glycop PF01528.16 OAJ32207.1 - 0.043 12.7 0.7 0.071 12.0 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus glycoprotein M Cu-oxidase_2 PF07731.14 OAJ32208.1 - 9.9e-40 135.5 3.6 3e-37 127.4 2.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 OAJ32208.1 - 1.4e-35 122.7 0.1 2.9e-32 112.0 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 OAJ32208.1 - 1.2e-25 89.8 7.8 6.6e-24 84.2 0.8 3.4 4 0 0 4 4 4 2 Multicopper oxidase DUF1690 PF07956.11 OAJ32209.1 - 6.8e-25 88.1 3.2 6.8e-25 88.1 3.2 2.1 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) Tcp11 PF05794.13 OAJ32209.1 - 0.0037 16.4 4.2 0.0064 15.6 4.2 1.4 1 0 0 1 1 1 1 T-complex protein 11 GIT1_C PF12205.8 OAJ32209.1 - 0.0093 16.1 0.3 0.0093 16.1 0.3 2.2 2 1 1 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term Apolipoprotein PF01442.18 OAJ32209.1 - 0.021 14.7 16.7 0.017 15.0 14.6 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Rootletin PF15035.6 OAJ32209.1 - 0.11 12.5 7.4 0.6 10.1 7.4 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 OAJ32209.1 - 0.44 10.8 3.3 0.65 10.3 1.4 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 OAJ32209.1 - 2.4 7.0 4.4 2.6 6.9 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lant_dehydr_C PF14028.6 OAJ32209.1 - 3.6 7.0 6.9 10 5.5 4.7 2.3 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF883 PF05957.13 OAJ32209.1 - 4.3 8.0 18.7 1.1 10.0 2.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) XRN_M PF17846.1 OAJ32209.1 - 5 6.0 6.9 4.8 6.0 6.3 1.3 1 1 0 1 1 1 0 Xrn1 helical domain Tape_meas_lam_C PF09718.10 OAJ32209.1 - 5.4 7.2 9.2 0.91 9.7 1.8 2.8 2 1 1 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Macoilin PF09726.9 OAJ32209.1 - 5.4 5.4 22.9 10 4.5 22.9 1.4 1 1 0 1 1 1 0 Macoilin family GREB1 PF15782.5 OAJ32209.1 - 5.7 3.9 9.7 5.8 3.9 9.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SlyX PF04102.12 OAJ32209.1 - 7.1 7.3 7.1 17 6.1 0.2 3.4 3 0 0 3 3 3 0 SlyX TP_methylase PF00590.20 OAJ32210.1 - 1.7e-16 60.9 0.4 6.4e-16 58.9 0.1 2.1 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L28 PF00830.19 OAJ32211.1 - 2.3e-20 72.5 0.2 4.3e-20 71.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Brix PF04427.18 OAJ32212.1 - 1.2e-30 107.0 0.1 1.6e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF4128 PF13554.6 OAJ32212.1 - 0.0042 17.1 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage related domain of unknown function DUF2517 PF10725.9 OAJ32212.1 - 0.031 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) T2SSF PF00482.23 OAJ32213.1 - 0.25 11.3 2.7 0.2 11.6 0.5 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F ubiquitin PF00240.23 OAJ32214.1 - 1.8e-68 226.2 6.8 9.5e-34 115.0 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 OAJ32214.1 - 1.3e-32 111.5 7.3 7.3e-16 57.8 0.8 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ32214.1 - 2e-12 47.4 2.3 0.00011 22.5 0.2 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ32214.1 - 3.1e-08 33.4 0.4 0.0084 16.0 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ32214.1 - 5.1e-08 33.2 0.6 0.011 16.0 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ32214.1 - 2.3e-07 30.9 0.5 0.035 14.2 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ32214.1 - 1.5e-06 28.7 0.1 0.074 13.6 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 OAJ32214.1 - 4.3e-05 23.5 8.5 6 7.0 0.2 4.0 4 0 0 4 4 4 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ32214.1 - 4.4e-05 23.4 0.1 0.25 11.2 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain HATPase_c PF02518.26 OAJ32214.1 - 0.00035 21.1 2.6 0.49 10.9 0.2 2.1 1 1 1 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3861 PF12977.7 OAJ32214.1 - 0.0034 17.5 0.3 2.7 8.2 0.0 2.2 1 1 1 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAJ32214.1 - 0.013 15.9 0.0 11 6.5 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 OAJ32214.1 - 0.021 15.6 0.1 11 6.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig domain ACT_5 PF13710.6 OAJ32214.1 - 0.021 14.6 0.5 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain NEAT PF05031.12 OAJ32214.1 - 0.048 14.3 0.2 0.084 13.5 0.2 1.5 1 1 0 1 1 1 0 Iron Transport-associated domain Big_3_3 PF13750.6 OAJ32214.1 - 0.049 13.3 0.0 10 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) YcgR_2 PF12945.7 OAJ32214.1 - 0.069 13.3 0.4 16 5.8 0.1 2.3 2 0 0 2 2 2 0 Flagellar protein YcgR DUF969 PF06149.12 OAJ32214.1 - 0.14 11.6 0.0 5.6 6.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Tash_PEST PF07708.11 OAJ32214.1 - 0.18 12.0 9.6 2.7 8.2 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif FERM_f0 PF16511.5 OAJ32214.1 - 0.25 11.7 1.2 44 4.5 0.1 3.2 2 2 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM Plexin_cytopl PF08337.12 OAJ32214.1 - 1.1 7.9 6.0 6.7 5.2 0.5 2.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain eIF_4EBP PF05456.11 OAJ32215.1 - 3.1e-10 40.0 0.9 3.1e-10 40.0 0.9 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Herpes_pp85 PF04637.12 OAJ32215.1 - 1.2 7.5 1.8 2.1 6.7 1.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ubiquitin PF00240.23 OAJ32216.1 - 1.4e-101 332.3 14.2 2.3e-33 113.7 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 OAJ32216.1 - 7.7e-48 160.2 14.9 1.8e-15 56.5 0.8 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ32216.1 - 1.2e-17 64.1 6.8 0.00026 21.4 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 OAJ32216.1 - 4.1e-12 45.9 2.5 0.018 15.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ32216.1 - 9.1e-12 45.2 2.6 0.028 14.8 0.1 3.1 1 1 0 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ32216.1 - 6.2e-11 42.4 1.6 0.078 13.1 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 OAJ32216.1 - 4.1e-10 40.2 0.5 0.17 12.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 OAJ32216.1 - 1.5e-07 31.4 0.3 0.61 9.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 OAJ32216.1 - 4.1e-06 26.8 16.7 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 OAJ32216.1 - 5.9e-05 23.2 1.2 6.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 OAJ32216.1 - 0.00024 21.4 0.0 20 5.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 OAJ32216.1 - 0.00032 20.1 0.2 0.83 8.9 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 OAJ32216.1 - 0.00036 21.2 0.1 22 5.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain ACT_5 PF13710.6 OAJ32216.1 - 0.0012 18.6 2.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain Big_3_3 PF13750.6 OAJ32216.1 - 0.0019 17.8 0.0 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 OAJ32216.1 - 0.0037 17.9 1.7 0.27 11.9 1.8 2.4 1 1 0 1 1 1 1 Iron Transport-associated domain DUF969 PF06149.12 OAJ32216.1 - 0.0045 16.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 OAJ32216.1 - 0.0087 16.2 3.5 4.1 7.6 0.1 3.2 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase YcgR_2 PF12945.7 OAJ32216.1 - 0.014 15.6 3.0 31 4.8 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR ACT_4 PF13291.6 OAJ32216.1 - 0.019 15.6 0.3 79 3.9 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF493 PF04359.14 OAJ32216.1 - 0.023 15.3 0.0 86 3.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 OAJ32216.1 - 0.032 13.9 0.1 72 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 OAJ32216.1 - 0.06 13.5 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain Tash_PEST PF07708.11 OAJ32216.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif ProRS-C_2 PF09181.10 OAJ32216.1 - 0.15 12.2 2.6 78 3.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 OAJ32216.1 - 0.23 11.3 3.4 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 OAJ32216.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 OAJ32216.1 - 0.46 10.4 5.1 62 3.6 0.1 3.4 3 0 0 3 3 3 0 FlgD Ig-like domain Phage_sheath_1N PF17481.2 OAJ32216.1 - 0.56 10.7 5.3 2.5e+02 2.2 5.3 3.1 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 OAJ32216.1 - 2.3 6.8 11.7 13 4.3 0.5 3.9 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 OAJ32216.1 - 5.1 6.9 6.0 98 2.8 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Hist_deacetyl PF00850.19 OAJ32217.1 - 2.2e-83 280.2 0.0 3.1e-83 279.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain SUIM_assoc PF16619.5 OAJ32217.1 - 0.79 9.8 9.7 0.028 14.5 2.4 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATP-synt_F PF01990.17 OAJ32218.1 - 4.5e-28 97.4 0.1 5.2e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF5427 PF10310.9 OAJ32219.1 - 1e-34 120.4 6.6 1.1e-33 116.9 2.7 2.9 1 1 1 2 2 2 1 Family of unknown function (DUF5427) Pardaxin PF07425.11 OAJ32219.1 - 0.069 12.8 1.0 0.22 11.2 1.0 1.8 1 0 0 1 1 1 0 Pardaxin DUF3439 PF11921.8 OAJ32219.1 - 4.9 7.1 10.8 12 5.9 10.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CBS PF00571.28 OAJ32221.1 - 1e-27 96.3 8.3 1.1e-06 29.0 0.1 5.4 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 OAJ32221.1 - 1.7e-06 27.9 0.0 9.8e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 PB1 domain SANT_DAMP1_like PF16282.5 OAJ32222.1 - 4.8e-30 103.6 2.2 8e-30 102.9 2.2 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Ribosomal_S27e PF01667.17 OAJ32223.1 - 2.9e-29 100.5 2.6 3.7e-29 100.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ32223.1 - 0.13 12.0 2.3 0.25 11.1 2.3 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ32223.1 - 0.19 11.5 4.4 0.48 10.3 0.3 2.4 1 1 2 3 3 3 0 Probable zinc-ribbon domain Ribosomal_S27e PF01667.17 OAJ32224.1 - 2.9e-29 100.5 2.6 3.7e-29 100.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 OAJ32224.1 - 0.13 12.0 2.3 0.25 11.1 2.3 1.5 1 1 0 1 1 1 0 CSL zinc finger zinc_ribbon_12 PF11331.8 OAJ32224.1 - 0.19 11.5 4.4 0.48 10.3 0.3 2.4 1 1 2 3 3 3 0 Probable zinc-ribbon domain Ribosomal_L19e PF01280.20 OAJ32225.1 - 1.7e-59 200.0 10.5 1.7e-59 200.0 10.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 OAJ32225.1 - 0.0079 15.9 0.2 0.029 14.1 0.2 2.0 1 0 0 1 1 1 1 S4 domain AA_permease_2 PF13520.6 OAJ32226.1 - 1.9e-80 270.8 38.5 2.3e-80 270.5 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 OAJ32226.1 - 2.3e-16 59.5 34.0 4.8e-16 58.4 33.8 1.4 1 1 0 1 1 1 1 Amino acid permease ATP12 PF07542.11 OAJ32227.1 - 2.8e-38 130.9 0.0 4.4e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Zn_clus PF00172.18 OAJ32228.1 - 7.2e-08 32.4 28.1 7.3e-06 26.0 8.5 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.21 OAJ32229.1 - 2.6e-41 140.4 0.1 2.9e-41 140.2 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Serglycin PF04360.12 OAJ32230.1 - 0.0012 18.8 0.8 0.0023 17.9 0.8 1.4 1 0 0 1 1 1 1 Serglycin Glyco_hydro_88 PF07470.13 OAJ32231.1 - 1.6e-15 57.0 0.8 2.7e-15 56.3 0.5 1.4 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF5329 PF17263.2 OAJ32231.1 - 0.044 14.0 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5329) EF_TS PF00889.19 OAJ32232.1 - 1.9e-12 47.3 0.0 2.1e-11 43.9 0.0 2.7 3 1 0 3 3 3 1 Elongation factor TS SPA PF08616.10 OAJ32233.1 - 1.2e-35 121.9 0.0 2.6e-35 120.8 0.0 1.6 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 OAJ32233.1 - 1.7e-24 86.8 0.1 3.1e-23 82.7 0.1 2.2 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 OAJ32233.1 - 5.2e-09 35.3 0.0 0.00014 20.7 0.0 3.5 2 2 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 OAJ32233.1 - 0.11 12.1 0.0 4.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FUSC_2 PF13515.6 OAJ32234.1 - 3.3e-16 59.6 17.1 3.3e-16 59.6 17.1 3.0 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 OAJ32234.1 - 4.4e-12 45.6 0.1 1.3e-11 44.1 0.1 1.8 1 1 0 1 1 1 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 OAJ32234.1 - 1.1e-08 34.6 0.1 1.1e-08 34.6 0.1 4.1 4 1 0 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 OAJ32234.1 - 5.7e-08 31.8 19.3 5.7e-08 31.8 19.3 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein family ArAE_1 PF06081.11 OAJ32234.1 - 6.7e-06 26.3 8.6 2.2e-05 24.7 8.6 1.9 1 0 0 1 1 1 1 Aromatic acid exporter family member 1 ArAE_2 PF10334.9 OAJ32234.1 - 4.8e-05 23.3 0.9 0.0002 21.3 1.3 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 MbeB_N PF04837.12 OAJ32234.1 - 0.27 11.6 3.1 0.38 11.1 0.2 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Ribonuc_2-5A PF06479.12 OAJ32236.1 - 3.2e-41 140.5 0.0 5.2e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 OAJ32236.1 - 1.8e-38 132.5 0.0 4.1e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32236.1 - 8e-20 71.2 0.0 5.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 OAJ32236.1 - 0.0002 20.8 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 OAJ32236.1 - 0.00023 20.1 0.0 0.00064 18.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 OAJ32236.1 - 0.00038 20.2 0.1 0.0072 16.2 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.6 OAJ32236.1 - 0.0042 16.7 0.1 0.32 10.5 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain SUIM_assoc PF16619.5 OAJ32236.1 - 0.9 9.7 6.4 0.13 12.4 1.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CitMHS PF03600.16 OAJ32238.1 - 9.6e-12 44.7 14.1 9.6e-12 44.7 14.1 2.1 2 1 0 2 2 2 1 Citrate transporter ArsB PF02040.15 OAJ32238.1 - 4.9e-11 42.6 17.1 8.2e-07 28.7 5.5 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein Nucleoporin_N PF08801.11 OAJ32239.1 - 4.2e-59 200.4 0.0 6.8e-59 199.7 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 OAJ32239.1 - 3.8e-33 115.1 5.1 6.1e-33 114.4 5.1 1.4 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal SMC_N PF02463.19 OAJ32240.1 - 1.2e-20 73.9 0.0 2.5e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ32240.1 - 2.2e-18 67.5 0.0 2.2e-18 67.5 0.0 5.9 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 OAJ32240.1 - 0.00013 21.7 0.1 0.0014 18.3 0.0 2.7 3 1 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.6 OAJ32240.1 - 0.0016 18.3 3.5 0.0028 17.5 0.3 3.0 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 OAJ32240.1 - 0.002 17.9 4.1 0.002 17.9 4.1 3.6 2 2 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 OAJ32240.1 - 0.096 13.2 0.0 0.096 13.2 0.0 5.1 3 2 0 3 3 3 0 ABC transporter Surfac_D-trimer PF09006.11 OAJ32240.1 - 7.7 6.5 7.0 8.9 6.3 0.7 3.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation AAA_13 PF13166.6 OAJ32240.1 - 9.3 4.7 66.0 2.8 6.5 0.0 4.8 3 2 1 4 4 4 0 AAA domain Peptidase_M28 PF04389.17 OAJ32241.1 - 3.8e-37 127.9 0.0 5.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 OAJ32241.1 - 0.017 14.8 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 DUF4449 PF14613.6 OAJ32242.1 - 0.00052 20.2 8.6 0.016 15.4 0.0 4.0 3 2 0 3 3 3 2 Protein of unknown function (DUF4449) Phage_tail_U PF06141.11 OAJ32242.1 - 0.0052 17.2 0.5 0.47 10.8 0.6 2.9 2 0 0 2 2 2 1 Phage minor tail protein U DASH_Duo1 PF08651.10 OAJ32242.1 - 0.028 14.2 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 0 DASH complex subunit Duo1 Laminin_I PF06008.14 OAJ32242.1 - 0.48 10.1 6.8 2.9 7.5 1.9 3.4 3 0 0 3 3 3 0 Laminin Domain I DUF445 PF04286.12 OAJ32242.1 - 1.4 8.7 15.0 2 8.1 8.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF445) SurE PF01975.17 OAJ32243.1 - 2.8e-41 141.4 0.0 2.2e-40 138.5 0.0 2.2 1 1 0 1 1 1 1 Survival protein SurE CLP1_P PF16575.5 OAJ32244.1 - 1.8e-27 96.4 0.0 2.2e-22 79.8 0.0 3.0 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 OAJ32244.1 - 2.1e-23 83.0 0.0 3.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 OAJ32244.1 - 2.4e-17 62.9 0.0 3.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_28 PF13521.6 OAJ32244.1 - 0.0067 16.7 0.1 0.029 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 OAJ32244.1 - 0.02 15.0 0.0 0.084 13.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pro_CA PF00484.19 OAJ32244.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase AAA_16 PF13191.6 OAJ32244.1 - 0.14 12.6 0.7 0.31 11.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 OAJ32245.1 - 0.00042 21.0 11.7 0.22 12.4 0.3 5.4 5 1 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ32245.1 - 0.00059 20.2 1.0 7 7.3 0.0 4.4 4 0 0 4 4 4 1 PQQ-like domain SAPS PF04499.15 OAJ32245.1 - 0.16 10.7 2.4 0.26 10.0 2.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 OAJ32245.1 - 0.54 8.4 25.3 0.99 7.5 25.3 1.4 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 OAJ32245.1 - 0.78 9.0 33.9 17 4.6 32.1 2.4 2 0 0 2 2 2 0 BUD22 TFIIA PF03153.13 OAJ32245.1 - 5.4 6.9 22.9 23 4.9 19.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ecl1 PF12855.7 OAJ32247.1 - 0.0021 19.3 5.5 0.0021 19.3 5.5 11.3 6 4 1 8 8 8 1 ECL1/2/3 zinc binding proteins Aa_trans PF01490.18 OAJ32248.1 - 1.5e-45 155.6 32.4 1.8e-45 155.4 32.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UCMA PF17085.5 OAJ32249.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.7 2 0 0 2 2 2 0 Unique cartilage matrix associated protein FAM176 PF14851.6 OAJ32249.1 - 0.66 9.6 5.3 2 8.1 0.0 2.7 3 0 0 3 3 3 0 FAM176 family Glyco_hydro_16 PF00722.21 OAJ32250.1 - 2.3e-33 115.1 0.9 4.5e-33 114.2 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 OAJ32250.1 - 0.063 13.8 17.4 0.15 12.6 17.4 1.6 1 0 0 1 1 1 0 Chitin recognition protein MutL_C PF08676.11 OAJ32251.1 - 4.3e-08 33.0 0.0 1.8e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 OAJ32251.1 - 0.0038 17.1 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 OAJ32251.1 - 0.0081 16.6 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMC_oxred_N PF00732.19 OAJ32252.1 - 4.5e-51 174.0 0.0 7.6e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 OAJ32252.1 - 3.5e-35 121.6 0.0 7.5e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 OAJ32252.1 - 0.00047 19.3 0.2 0.00088 18.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAJ32252.1 - 0.0016 17.6 0.0 0.052 12.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 OAJ32252.1 - 0.002 18.3 0.6 0.007 16.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 OAJ32252.1 - 0.0033 16.7 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 OAJ32252.1 - 0.15 12.3 0.2 0.34 11.2 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 OAJ32252.1 - 0.3 10.6 5.9 0.24 10.9 0.9 3.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase Phage_Gp23 PF10669.9 OAJ32252.1 - 5.5 7.3 8.2 8.8 6.7 8.2 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) SGS PF05002.15 OAJ32253.1 - 1.8e-29 101.7 1.6 3.6e-29 100.7 1.6 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 OAJ32253.1 - 1.1e-09 39.2 0.0 1.9e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 CS domain Methyltransf_28 PF02636.17 OAJ32254.1 - 7.9e-64 215.8 0.0 1.2e-63 215.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CRAL_TRIO PF00650.20 OAJ32256.1 - 1.6e-34 119.0 0.0 2.4e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 OAJ32256.1 - 2.2e-10 40.6 0.2 7.6e-10 38.8 0.4 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain ThiS PF02597.20 OAJ32256.1 - 6.5e-08 33.1 0.1 5.6e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 ThiS family TFIIA PF03153.13 OAJ32256.1 - 0.091 12.7 27.6 0.12 12.3 16.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Uds1 PF15456.6 OAJ32257.1 - 6.9e-21 74.8 4.3 6.9e-21 74.8 4.3 14.1 5 2 6 11 11 11 1 Up-regulated During Septation DUF3786 PF12654.7 OAJ32257.1 - 1.8 8.1 4.9 3.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3786) NAD_binding_8 PF13450.6 OAJ32258.1 - 3e-08 33.8 0.0 8.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ32258.1 - 7.1e-08 32.4 0.1 3.5e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 OAJ32258.1 - 1.6e-07 31.5 0.2 0.028 14.4 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 OAJ32258.1 - 1.5e-06 27.7 0.0 0.0063 15.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 OAJ32258.1 - 3.5e-06 25.7 0.0 0.15 10.4 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 OAJ32258.1 - 2.7e-05 23.5 0.0 0.0097 15.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 OAJ32258.1 - 0.00074 18.9 0.0 0.23 10.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 OAJ32258.1 - 0.001 19.2 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 OAJ32258.1 - 0.016 14.4 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 OAJ32258.1 - 0.034 12.9 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 OAJ32258.1 - 0.044 12.9 0.1 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 OAJ32258.1 - 0.077 12.3 0.0 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 OAJ32258.1 - 0.078 12.0 0.0 9.7 5.1 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 OAJ32258.1 - 0.086 12.1 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain E3_binding PF02817.17 OAJ32259.1 - 3e-06 27.5 0.1 5.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain Response_reg PF00072.24 OAJ32260.1 - 1.8e-07 31.3 0.0 6.5e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain DAAD PF18752.1 OAJ32260.1 - 2.6 7.8 5.3 8.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase SNRNP27 PF08648.12 OAJ32262.1 - 4.8e-26 90.6 1.8 7.6e-26 90.0 0.4 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Pkinase PF00069.25 OAJ32263.1 - 1.8e-62 211.1 0.0 2.2e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32263.1 - 5e-33 114.5 0.0 6.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ32263.1 - 1.6e-07 30.4 0.0 2.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 OAJ32263.1 - 0.0001 21.7 0.0 0.00025 20.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 OAJ32263.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 OAJ32263.1 - 0.042 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 OAJ32263.1 - 0.093 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 OAJ32263.1 - 0.21 11.1 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SET PF00856.28 OAJ32264.1 - 1e-09 39.0 0.0 1e-09 39.0 0.0 3.2 3 1 0 3 3 3 1 SET domain Cytochrom_NNT PF03264.14 OAJ32264.1 - 0.038 13.7 1.2 0.086 12.5 1.2 1.5 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DNA_pol_phi PF04931.13 OAJ32264.1 - 6.4 4.7 17.2 10 4.0 17.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi TPMT PF05724.11 OAJ32265.1 - 1.6e-33 116.2 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 OAJ32265.1 - 6.3e-10 39.6 0.0 9.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 OAJ32265.1 - 1.6e-08 34.5 0.0 2.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 OAJ32265.1 - 1.7e-08 35.0 0.0 2.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 OAJ32265.1 - 6.3e-06 26.9 0.0 1.7e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 OAJ32265.1 - 8.5e-06 25.7 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF1708 PF08101.11 OAJ32267.1 - 4.6e-26 91.9 0.3 1.4e-18 67.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 OAJ32267.1 - 4.7e-05 23.3 0.0 0.00035 20.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain HAMP_N3 PF18575.1 OAJ32267.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 HAMP N-terminal domain 3 DNA_pol_phi PF04931.13 OAJ32268.1 - 1.4 6.9 3.9 2.6 6.0 3.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi PsiA PF06952.11 OAJ32269.1 - 0.044 13.0 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Cas_DxTHG PF09455.10 OAJ32269.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Peptidase_C65 PF10275.9 OAJ32272.1 - 6.7e-62 209.1 0.0 8.5e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 OAJ32272.1 - 0.0054 17.2 0.0 0.085 13.3 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Zn_clus PF00172.18 OAJ32273.1 - 0.00032 20.7 12.0 0.00054 20.0 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4179 PF13786.6 OAJ32273.1 - 0.0012 19.3 0.1 31 5.1 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4179) DUF3464 PF11947.8 OAJ32273.1 - 3 7.6 6.6 0.48 10.2 2.2 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 His_Phos_1 PF00300.22 OAJ32274.1 - 1.4e-08 34.7 0.0 3.7e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 OAJ32274.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) zf-RING_4 PF14570.6 OAJ32275.1 - 1.8e-21 75.7 11.6 2.8e-21 75.0 11.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 OAJ32275.1 - 1.6e-06 27.9 8.9 2.6e-06 27.2 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ32275.1 - 0.0001 22.1 9.0 0.0069 16.2 9.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Spt20 PF12090.8 OAJ32275.1 - 0.0061 16.2 11.9 0.0061 16.2 11.9 7.4 5 1 0 5 5 5 1 Spt20 family zf-RING_2 PF13639.6 OAJ32275.1 - 0.0063 16.8 11.8 0.011 16.0 11.8 1.4 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 OAJ32275.1 - 0.012 15.6 0.0 0.012 15.6 0.0 7.0 3 2 4 7 7 7 0 Transcription factor IIA, alpha/beta subunit zf-UDP PF14569.6 OAJ32275.1 - 0.041 14.0 4.0 0.091 12.9 4.0 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_1 PF00076.22 OAJ32275.1 - 0.048 13.5 0.0 0.21 11.4 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 OAJ32275.1 - 1.3 9.0 11.5 2.3 8.2 11.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 OAJ32275.1 - 1.4 8.8 7.8 1.1 9.2 6.2 1.7 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Vps55 PF04133.14 OAJ32276.1 - 3.3e-42 143.1 7.7 3.7e-42 143.0 7.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Phosducin PF02114.16 OAJ32277.1 - 0.04 12.9 2.1 6.2 5.7 1.6 2.3 2 0 0 2 2 2 0 Phosducin GCIP PF13324.6 OAJ32277.1 - 1.6 8.3 8.6 0.61 9.7 2.9 2.4 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting GOLD_2 PF13897.6 OAJ32277.1 - 2.4 8.6 8.1 0.14 12.7 1.7 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Cwf_Cwc_15 PF04889.12 OAJ32277.1 - 2.4 7.8 19.1 0.37 10.5 12.9 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Response_reg PF00072.24 OAJ32278.1 - 2.3e-23 82.5 0.0 5.2e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 OAJ32278.1 - 3.8e-18 66.0 0.0 7.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PBP1_TM PF14812.6 OAJ32280.1 - 2.4 8.6 6.2 6.9 7.1 2.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 OAJ32280.1 - 5.6 7.4 10.4 13 6.3 5.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4407 PF14362.6 OAJ32281.1 - 0.14 11.5 4.3 0.15 11.4 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ThiF PF00899.21 OAJ32282.1 - 1.2e-58 198.4 0.0 1.7e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 OAJ32282.1 - 1.1e-05 25.9 0.0 3.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain NAD_binding_7 PF13241.6 OAJ32282.1 - 1.2e-05 25.7 0.1 2.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 OAJ32282.1 - 2.6e-05 24.3 0.1 0.00025 21.1 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 OAJ32282.1 - 0.0062 16.1 0.1 0.0096 15.5 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 OAJ32282.1 - 0.13 11.8 0.3 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GCV_H PF01597.19 OAJ32282.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein AAA_5 PF07728.14 OAJ32283.1 - 1.6e-113 374.8 0.2 1.9e-19 70.0 0.0 10.2 9 1 1 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 OAJ32283.1 - 1.5e-44 150.5 2.3 1.5e-15 57.2 0.0 4.6 3 0 0 3 3 3 3 Midasin AAA lid domain AAA_7 PF12775.7 OAJ32283.1 - 5e-27 94.6 0.5 1.5e-06 27.8 0.0 7.1 7 0 0 7 7 7 4 P-loop containing dynein motor region AAA PF00004.29 OAJ32283.1 - 1.7e-26 93.2 0.2 0.0056 17.1 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 OAJ32283.1 - 3.2e-25 88.5 0.0 6.9e-08 32.4 0.0 7.7 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 OAJ32283.1 - 3.2e-22 78.6 0.0 9.6e-22 77.1 0.0 1.8 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 OAJ32283.1 - 2.3e-21 76.9 44.7 0.00011 22.6 0.4 12.1 10 4 0 11 11 9 6 AAA ATPase domain AAA_22 PF13401.6 OAJ32283.1 - 3.4e-20 72.7 3.6 0.0043 17.3 0.0 8.4 8 0 0 8 8 7 3 AAA domain ABC_tran PF00005.27 OAJ32283.1 - 2e-17 64.0 0.3 0.0031 18.0 0.0 6.9 6 1 0 6 6 5 3 ABC transporter AAA_6 PF12774.7 OAJ32283.1 - 7.7e-17 61.2 0.2 0.014 14.4 0.0 6.8 6 0 0 6 6 6 4 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 OAJ32283.1 - 1.1e-16 61.0 0.0 0.031 14.4 0.0 7.1 6 0 0 6 6 6 3 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 OAJ32283.1 - 4e-16 59.2 0.1 0.0049 16.6 0.0 5.9 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_18 PF13238.6 OAJ32283.1 - 2.5e-15 57.2 0.4 0.09 13.3 0.0 7.2 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 OAJ32283.1 - 1.4e-14 54.3 10.1 0.15 11.8 0.0 8.7 7 1 0 7 7 7 4 AAA domain TsaE PF02367.17 OAJ32283.1 - 3.9e-14 52.7 4.8 0.089 12.8 0.1 7.1 7 0 0 7 7 7 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ32283.1 - 1.3e-13 51.3 2.5 0.0095 16.1 0.2 7.3 6 0 0 6 6 6 2 AAA domain NACHT PF05729.12 OAJ32283.1 - 3.7e-12 46.5 2.1 0.0036 17.2 0.0 6.3 5 0 0 5 5 5 2 NACHT domain AAA_14 PF13173.6 OAJ32283.1 - 7.9e-11 42.1 0.0 0.071 13.1 0.0 6.6 8 0 0 8 8 5 2 AAA domain AAA_19 PF13245.6 OAJ32283.1 - 5.7e-10 39.7 8.8 0.23 11.8 0.1 6.9 6 1 0 6 6 5 2 AAA domain AAA_28 PF13521.6 OAJ32283.1 - 1e-09 38.9 8.0 1.7 8.9 0.0 7.5 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.6 OAJ32283.1 - 1.2e-09 37.8 1.3 0.28 11.0 0.0 6.0 6 0 0 6 6 5 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 OAJ32283.1 - 2.4e-09 37.6 0.6 1.3 9.4 0.0 6.7 6 0 0 6 6 6 1 RNA helicase RsgA_GTPase PF03193.16 OAJ32283.1 - 5.8e-09 36.1 4.2 0.13 12.1 0.0 6.3 6 1 1 7 7 6 2 RsgA GTPase Mg_chelatase PF01078.21 OAJ32283.1 - 6.5e-09 35.5 5.3 0.13 11.6 0.1 7.8 8 0 0 8 8 7 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 OAJ32283.1 - 9.9e-09 34.8 2.5 0.21 10.8 0.0 6.3 6 0 0 6 6 6 1 Zeta toxin Sigma54_activ_2 PF14532.6 OAJ32283.1 - 1.1e-08 35.2 0.5 0.41 10.8 0.0 6.0 5 0 0 5 5 5 2 Sigma-54 interaction domain T2SSE PF00437.20 OAJ32283.1 - 2.5e-08 33.3 7.0 0.13 11.3 0.0 6.6 6 0 0 6 6 6 1 Type II/IV secretion system protein DUF815 PF05673.13 OAJ32283.1 - 6.8e-08 32.0 2.4 0.4 9.8 0.0 6.0 6 0 0 6 6 6 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 OAJ32283.1 - 2.6e-07 30.4 15.2 0.83 9.2 0.1 6.8 7 0 0 7 7 6 2 AAA domain IstB_IS21 PF01695.17 OAJ32283.1 - 2.7e-07 30.5 1.1 1 9.1 0.0 5.9 6 0 0 6 6 6 1 IstB-like ATP binding protein Roc PF08477.13 OAJ32283.1 - 1.1e-06 28.9 1.3 3.6 7.8 0.0 5.9 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 OAJ32283.1 - 1.5e-06 28.1 1.0 2.5 7.8 0.0 6.0 6 0 0 6 6 6 1 AAA domain TniB PF05621.11 OAJ32283.1 - 2.1e-06 27.3 0.0 4.3 6.7 0.0 5.2 5 0 0 5 5 5 0 Bacterial TniB protein PduV-EutP PF10662.9 OAJ32283.1 - 2.9e-06 27.1 2.1 0.52 10.1 0.0 5.2 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 OAJ32283.1 - 1.5e-05 25.0 0.6 1.4 8.8 0.0 5.2 5 0 0 5 5 5 1 Rad17 P-loop domain ResIII PF04851.15 OAJ32283.1 - 2e-05 24.7 0.1 5.5 7.0 0.0 5.4 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit AAA_21 PF13304.6 OAJ32283.1 - 2.6e-05 24.2 3.0 11 5.7 0.0 5.6 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 OAJ32283.1 - 0.00012 22.1 0.5 34 4.6 0.0 6.0 6 0 0 6 6 5 0 50S ribosome-binding GTPase SRP54 PF00448.22 OAJ32283.1 - 0.00014 21.6 5.6 1.1 8.8 0.0 5.4 5 0 0 5 5 4 1 SRP54-type protein, GTPase domain RuvB_N PF05496.12 OAJ32283.1 - 0.00024 20.9 4.8 18 5.0 0.0 6.6 7 0 0 7 7 7 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 OAJ32283.1 - 0.00033 20.1 1.0 7.3 5.9 0.0 4.8 5 0 0 5 5 5 0 KaiC AAA_8 PF12780.7 OAJ32283.1 - 0.00057 19.3 0.1 13 5.0 0.0 4.6 4 0 0 4 4 4 0 P-loop containing dynein motor region D4 MeaB PF03308.16 OAJ32283.1 - 0.00067 18.7 2.5 0.92 8.4 0.0 3.4 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 OAJ32283.1 - 0.0011 18.3 3.7 3.3 6.8 0.0 4.7 5 0 0 5 5 5 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 OAJ32283.1 - 0.0016 18.3 0.2 17 5.1 0.0 5.3 6 0 0 6 6 5 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 OAJ32283.1 - 0.0016 18.1 8.4 7.3 6.1 0.0 5.5 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 OAJ32283.1 - 0.0029 17.0 0.4 38 3.6 0.0 5.5 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit PhoH PF02562.16 OAJ32283.1 - 0.0036 16.8 2.7 3.4 7.1 0.1 4.0 4 0 0 4 4 4 0 PhoH-like protein ATP_bind_1 PF03029.17 OAJ32283.1 - 0.0091 15.8 2.1 12 5.6 0.1 4.4 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein CPT PF07931.12 OAJ32283.1 - 0.0096 15.8 9.8 1.8 8.4 0.0 7.5 10 1 0 10 10 7 1 Chloramphenicol phosphotransferase-like protein MCM PF00493.23 OAJ32283.1 - 0.01 14.9 0.0 25 3.9 0.0 4.3 4 0 0 4 4 4 0 MCM P-loop domain ATPase_2 PF01637.18 OAJ32283.1 - 0.015 15.2 0.0 23 4.8 0.0 4.3 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 OAJ32283.1 - 0.017 15.1 3.9 5.4 6.9 0.1 5.0 5 0 0 5 5 5 0 NTPase dNK PF01712.19 OAJ32283.1 - 0.038 13.8 2.5 26 4.6 0.0 4.3 5 0 0 5 5 4 0 Deoxynucleoside kinase AAA_23 PF13476.6 OAJ32283.1 - 0.05 14.1 0.0 0.05 14.1 0.0 7.6 7 1 0 7 7 6 0 AAA domain IPT PF01745.16 OAJ32283.1 - 0.051 13.0 1.4 26 4.1 0.0 3.9 4 0 0 4 4 4 0 Isopentenyl transferase Bac_DnaA PF00308.18 OAJ32283.1 - 0.059 13.2 0.0 7.6 6.3 0.0 3.3 3 0 0 3 3 2 0 Bacterial dnaA protein Ploopntkinase3 PF18751.1 OAJ32283.1 - 0.086 12.7 0.2 20 5.0 0.0 3.7 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 OAJ32283.1 - 0.092 12.1 4.0 4.4 6.6 0.1 4.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family Ferritin_2 PF13668.6 OAJ32284.1 - 1.6e-10 41.3 0.0 2.6e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Pyr_redox_2 PF07992.14 OAJ32285.1 - 6.5e-66 222.5 0.2 9.7e-66 222.0 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 OAJ32285.1 - 8e-33 113.0 1.2 1.9e-32 111.8 1.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 OAJ32285.1 - 2.1e-19 69.9 4.1 8.8e-18 64.7 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PAP2 PF01569.21 OAJ32285.1 - 4.1e-13 49.3 3.1 1.3e-12 47.6 3.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily Pyr_redox_3 PF13738.6 OAJ32285.1 - 6.3e-12 45.4 0.1 4.4e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 OAJ32285.1 - 5.3e-06 25.4 0.7 0.027 13.2 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein K_oxygenase PF13434.6 OAJ32285.1 - 0.00015 21.1 0.0 0.00063 19.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 OAJ32285.1 - 0.00021 20.8 0.8 0.00044 19.7 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase UbiA PF01040.18 OAJ32285.1 - 0.02 14.2 7.8 0.014 14.7 1.6 2.3 2 0 0 2 2 2 0 UbiA prenyltransferase family UPF0542 PF15086.6 OAJ32285.1 - 0.021 14.7 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 NAD_binding_8 PF13450.6 OAJ32285.1 - 0.033 14.4 1.4 0.11 12.8 1.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 OAJ32285.1 - 0.089 12.7 2.9 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 OAJ32285.1 - 0.15 11.1 2.7 0.56 9.2 2.1 2.1 2 0 0 2 2 2 0 FAD binding domain Apolipoprotein PF01442.18 OAJ32286.1 - 0.0015 18.4 4.0 0.0021 18.0 4.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Coiled-coil_56 PF09813.9 OAJ32286.1 - 0.0084 16.1 0.2 0.018 15.1 0.0 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 DUF883 PF05957.13 OAJ32286.1 - 0.023 15.3 6.9 0.055 14.1 6.7 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) SARAF PF06682.12 OAJ32286.1 - 0.025 14.2 4.4 0.028 14.1 4.2 1.3 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Uso1_p115_C PF04871.13 OAJ32286.1 - 0.041 14.2 3.4 0.054 13.9 3.4 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Aminotran_5 PF00266.19 OAJ32286.1 - 0.05 12.5 0.7 0.071 12.1 0.7 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Inv-AAD PF18785.1 OAJ32287.1 - 1.8e-23 82.8 0.0 3.8e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 OAJ32287.1 - 1.1e-11 44.5 0.0 2.1e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 OAJ32287.1 - 7.6e-08 32.5 0.1 1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 OAJ32287.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 OAJ32287.1 - 0.022 14.9 0.0 0.36 10.9 0.0 2.3 1 1 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 OAJ32287.1 - 0.14 12.2 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 Ras PF00071.22 OAJ32288.1 - 3.7e-34 117.7 0.3 4.5e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ32288.1 - 2.5e-26 92.2 0.1 4.2e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ32288.1 - 9.8e-08 31.6 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ32288.1 - 4.4e-07 29.5 0.3 5.7e-07 29.1 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ32288.1 - 0.027 13.6 2.7 0.092 11.9 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit MID_MedPIWI PF18296.1 OAJ32288.1 - 0.033 14.0 0.2 0.056 13.2 0.2 1.4 1 0 0 1 1 1 0 MID domain of medPIWI MMR_HSR1 PF01926.23 OAJ32288.1 - 0.051 13.6 0.0 0.081 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ32288.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 OAJ32288.1 - 0.1 12.0 0.0 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein DLIC PF05783.11 OAJ32288.1 - 0.13 11.1 8.6 0.15 10.8 0.0 2.9 1 1 2 3 3 3 0 Dynein light intermediate chain (DLIC) Utp21 PF04192.12 OAJ32289.1 - 2.7e-52 177.6 0.0 9.1e-52 175.9 0.0 1.8 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 OAJ32289.1 - 1.4e-15 57.3 0.0 0.0013 19.0 0.0 7.3 5 2 3 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ32289.1 - 1.5e-09 38.3 11.0 0.019 15.8 0.1 7.6 8 0 0 8 8 8 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 OAJ32289.1 - 0.013 15.5 0.0 0.32 11.1 0.0 3.2 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 OAJ32289.1 - 0.015 14.3 0.0 4 6.3 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 OAJ32289.1 - 0.02 15.4 3.6 7.4 7.2 0.5 5.2 4 1 0 4 4 4 0 PQQ-like domain PBP1_TM PF14812.6 OAJ32289.1 - 0.064 13.6 1.7 0.18 12.2 1.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PD40 PF07676.12 OAJ32289.1 - 0.083 12.9 0.3 0.28 11.2 0.3 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SR-25 PF10500.9 OAJ32289.1 - 7.7 6.1 19.3 0.16 11.5 12.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BolA PF01722.18 OAJ32290.1 - 7e-16 58.3 0.1 1.1e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 OAJ32291.1 - 1.5e-89 300.5 0.1 2e-89 300.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ32291.1 - 0.0026 18.7 0.0 0.0097 16.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 OAJ32292.1 - 1.5e-12 47.1 0.0 2.4e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.13 OAJ32292.1 - 4.1 6.4 6.1 5.7 5.9 6.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RNA_pol_Rpb1_5 PF04998.17 OAJ32293.1 - 1.6e-88 296.6 0.0 3.2e-88 295.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 OAJ32293.1 - 1.4e-63 214.0 0.0 2.6e-63 213.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 OAJ32293.1 - 5.4e-34 117.4 0.0 1.1e-33 116.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 OAJ32293.1 - 1.7e-29 103.2 0.3 3e-23 82.6 0.0 4.2 5 0 0 5 5 5 3 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 OAJ32293.1 - 8.1e-22 77.2 0.0 2.8e-21 75.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Il13Ra_Ig PF18001.1 OAJ32293.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain DUF913 PF06025.12 OAJ32293.1 - 6 5.7 7.5 15 4.5 4.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) C2 PF00168.30 OAJ32294.1 - 3.1e-72 239.4 0.2 1.4e-21 76.7 0.0 4.4 4 0 0 4 4 4 4 C2 domain MMM1 PF10296.9 OAJ32294.1 - 0.083 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 W2 PF02020.18 OAJ32295.1 - 6.4e-14 51.8 2.2 6.4e-14 51.8 2.2 3.5 3 2 1 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 OAJ32295.1 - 1.4e-08 34.2 1.1 8.7e-05 22.1 0.2 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 OAJ32295.1 - 1.3e-05 24.9 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 OAJ32295.1 - 0.0022 17.0 0.1 0.0039 16.2 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 OAJ32295.1 - 0.0035 17.1 2.6 0.029 14.1 2.6 2.4 1 1 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 OAJ32295.1 - 0.012 16.0 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain Glyco_tranf_2_4 PF13704.6 OAJ32295.1 - 0.041 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 BUD22 PF09073.10 OAJ32295.1 - 0.85 8.9 38.3 0.062 12.6 20.7 2.2 2 0 0 2 2 2 0 BUD22 Lin-8 PF03353.15 OAJ32295.1 - 5.6 6.4 6.3 14 5.2 6.3 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Autophagy_N PF03986.13 OAJ32296.1 - 4e-42 143.4 0.0 7.7e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 OAJ32296.1 - 1.5e-18 67.1 0.1 2.9e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 OAJ32296.1 - 4.1e-11 42.2 0.4 7.1e-11 41.4 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF3915 PF13054.6 OAJ32297.1 - 0.14 12.1 0.3 0.14 12.1 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) Mob1_phocein PF03637.17 OAJ32298.1 - 3.2e-21 76.1 0.0 4.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Vfa1 PF08432.10 OAJ32298.1 - 0.0065 16.8 0.3 0.01 16.2 0.3 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 adh_short_C2 PF13561.6 OAJ32299.1 - 1.5e-53 181.8 0.0 2e-53 181.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ32299.1 - 1.9e-43 148.2 0.1 2.3e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ32299.1 - 4.9e-12 46.1 0.0 6.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Requiem_N PF14051.6 OAJ32300.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Cofilin_ADF PF00241.20 OAJ32301.1 - 1e-19 70.5 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_9 PF14604.6 OAJ32301.1 - 2.5e-12 46.5 0.3 2.5e-12 46.5 0.3 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 OAJ32301.1 - 8.8e-12 44.5 1.2 1.8e-11 43.5 0.2 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 OAJ32301.1 - 2e-06 27.4 0.0 2.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Mgm101p PF06420.12 OAJ32302.1 - 1.4e-82 275.3 0.0 1.8e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF2235 PF09994.9 OAJ32303.1 - 6.9e-73 245.5 0.0 9.3e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAJ32304.1 - 8.1e-73 245.3 0.0 1.1e-72 244.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 OAJ32305.1 - 2.2e-71 240.6 0.0 2.9e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Gln-synt_C PF00120.24 OAJ32306.1 - 6.5e-15 55.0 0.0 6.8e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 OAJ32306.1 - 6.5e-13 48.2 0.0 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FAD_binding_2 PF00890.24 OAJ32306.1 - 0.074 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DUF2235 PF09994.9 OAJ32307.1 - 9.8e-58 195.8 1.6 1.4e-35 123.0 0.2 2.3 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2828 PF11443.8 OAJ32308.1 - 8.8e-204 678.2 0.0 1.1e-203 677.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) adh_short_C2 PF13561.6 OAJ32309.1 - 4.1e-42 144.3 0.1 5.7e-42 143.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ32309.1 - 9.5e-41 139.4 0.1 1.9e-40 138.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ32309.1 - 5.7e-08 32.9 0.1 9.7e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Ras PF00071.22 OAJ32310.1 - 4.9e-58 195.3 0.0 5.6e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ32310.1 - 5.8e-23 81.4 0.0 8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ32310.1 - 7.3e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 OAJ32310.1 - 0.0005 19.7 0.0 0.0014 18.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 OAJ32310.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Asp PF00026.23 OAJ32311.1 - 1.5e-28 100.2 0.0 4.8e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ32311.1 - 0.0016 18.7 1.3 0.025 14.8 1.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ32311.1 - 0.051 14.2 0.0 5.6 7.7 0.0 3.1 2 1 0 2 2 2 0 Aspartyl protease DNA_pol_B PF00136.21 OAJ32312.1 - 2.8e-99 332.9 0.0 3.5e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 OAJ32312.1 - 4.9e-23 81.8 0.0 2.3e-13 50.0 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 OAJ32312.1 - 1e-11 45.1 6.2 2e-11 44.2 6.2 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta HEAT PF02985.22 OAJ32313.1 - 6.3e-35 116.2 20.2 0.01 16.0 0.0 13.8 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 OAJ32313.1 - 1.1e-32 112.2 10.5 1.4e-11 44.6 0.0 6.9 3 3 4 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 OAJ32313.1 - 2.2e-10 40.8 16.3 0.84 10.2 0.1 8.2 7 1 1 8 8 8 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 OAJ32313.1 - 4.5e-10 40.0 0.9 0.063 13.9 0.1 6.6 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 OAJ32313.1 - 2.4e-07 31.0 9.2 0.016 15.3 0.1 5.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 OAJ32313.1 - 0.00038 19.1 4.9 0.049 12.2 0.2 4.1 4 1 0 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.8 OAJ32313.1 - 0.00075 19.1 0.9 0.019 14.5 0.1 3.6 1 1 2 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 OAJ32313.1 - 0.029 14.5 3.9 9.5 6.4 0.1 3.9 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 API5 PF05918.11 OAJ32313.1 - 0.041 12.7 0.5 0.17 10.7 0.0 2.3 3 0 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) M11L PF11099.8 OAJ32313.1 - 0.1 12.8 0.3 8.1 6.7 0.1 2.9 2 1 0 2 2 2 0 Apoptosis regulator M11L like MMM1 PF10296.9 OAJ32314.1 - 5.8e-68 229.4 0.0 4.2e-47 160.8 0.0 2.6 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Vps39_1 PF10366.9 OAJ32317.1 - 3.4e-28 98.1 0.8 1e-27 96.5 0.2 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 OAJ32317.1 - 5.7e-19 68.6 0.7 1.3e-18 67.4 0.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 OAJ32317.1 - 1.3e-13 51.2 0.0 2.9e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 CNH domain Clathrin PF00637.20 OAJ32317.1 - 3.1e-08 33.6 5.3 4.1e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_19 PF14559.6 OAJ32317.1 - 0.2 12.2 6.4 0.63 10.6 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ32317.1 - 0.46 10.4 4.2 2.2 8.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 OAJ32319.1 - 4.8e-28 98.1 33.0 6.6e-28 97.6 33.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.22 OAJ32320.1 - 2.9e-129 431.6 0.0 3.4e-129 431.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family S-methyl_trans PF02574.16 OAJ32321.1 - 5.2e-51 174.0 0.0 6.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DnaJ PF00226.31 OAJ32322.1 - 1.2e-19 70.1 0.5 2.3e-19 69.3 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 OAJ32322.1 - 0.00031 20.8 3.1 0.00063 19.8 3.1 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 OAJ32322.1 - 0.074 13.1 6.7 0.19 11.8 6.7 1.6 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.6 OAJ32322.1 - 0.67 9.8 9.1 2.7 7.9 9.1 2.0 1 1 0 1 1 1 0 Glycine-zipper domain SUR7 PF06687.12 OAJ32323.1 - 2.2e-07 30.8 0.0 4.9e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 SUR7/PalI family HCMV_UL139 PF12507.8 OAJ32323.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3112 PF11309.8 OAJ32323.1 - 0.52 9.7 6.3 0.075 12.5 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) ATF7IP_BD PF16788.5 OAJ32323.1 - 8 6.5 8.2 12 5.9 8.2 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain PSK PF06404.12 OAJ32324.1 - 0.049 14.7 0.8 0.06 14.4 0.8 1.6 1 1 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Uso1_p115_head PF04869.14 OAJ32325.1 - 9.5e-43 146.5 0.0 4.3e-28 98.4 0.0 3.9 4 0 0 4 4 4 3 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 OAJ32325.1 - 1.3e-12 48.2 22.9 1.3e-12 48.2 22.9 3.5 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 OAJ32325.1 - 0.0074 16.3 3.6 0.08 13.0 0.0 3.6 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Cep57_MT_bd PF06657.13 OAJ32325.1 - 3.4 8.2 22.0 0.14 12.6 1.2 4.0 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 RVT_1 PF00078.27 OAJ32326.1 - 1.4e-14 54.1 0.0 2.3e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HEAT PF02985.22 OAJ32327.1 - 3.5e-05 23.7 15.7 0.28 11.5 0.1 8.6 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 OAJ32327.1 - 0.0003 21.1 10.8 2.1 8.8 0.0 6.9 5 1 0 5 5 5 2 HEAT repeats IFRD PF05004.13 OAJ32327.1 - 0.0021 17.3 14.6 0.0043 16.2 0.0 5.4 6 0 0 6 6 6 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 OAJ32327.1 - 0.0024 17.9 0.4 4.6 7.3 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 OAJ32327.1 - 0.019 15.0 0.2 0.019 15.0 0.2 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 OAJ32327.1 - 0.052 12.7 0.5 22 4.1 0.2 4.3 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 OAJ32327.1 - 0.75 10.4 22.8 1.7 9.2 0.6 7.4 7 0 0 7 7 7 0 HEAT-like repeat RhoGEF PF00621.20 OAJ32328.1 - 1e-17 64.9 0.0 1.9e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3381 PF11861.8 OAJ32329.1 - 0.0053 16.6 0.0 0.0066 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) YqcI_YcgG PF08892.11 OAJ32330.1 - 0.016 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 YqcI/YcgG family ROQ_II PF18386.1 OAJ32331.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Roquin II domain PUF PF00806.19 OAJ32332.1 - 6.4e-59 192.5 16.5 6.6e-08 31.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RA PF00788.23 OAJ32332.1 - 0.1 13.2 0.3 1.1 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain CoaE PF01121.20 OAJ32333.1 - 9.9e-58 194.7 0.0 1.7e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 OAJ32333.1 - 0.00064 20.3 0.0 0.0027 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 OAJ32333.1 - 0.0047 17.1 0.1 0.023 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain SKI PF01202.22 OAJ32333.1 - 0.0056 16.8 0.0 0.025 14.7 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase T3SS_ExsE PF18286.1 OAJ32333.1 - 0.19 11.7 1.0 0.57 10.2 0.2 2.1 2 0 0 2 2 2 0 Type III secretion system ExsE Sybindin PF04099.12 OAJ32338.1 - 2.1e-07 31.0 0.4 3.9e-07 30.1 0.4 1.4 1 1 0 1 1 1 1 Sybindin-like family ODV-E18 PF10717.9 OAJ32339.1 - 0.034 14.0 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 SMK-1 PF04802.15 OAJ32340.1 - 1e-77 260.3 2.1 2.3e-77 259.2 2.1 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Cys_rich_CPCC PF14206.6 OAJ32341.1 - 0.04 13.7 3.3 0.058 13.2 3.3 1.3 1 0 0 1 1 1 0 Cysteine-rich CPCC Glyco_hydro_79C PF16862.5 OAJ32342.1 - 2.2e-13 51.0 0.0 4.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF4336 PF14234.6 OAJ32343.1 - 0.00019 20.7 0.0 0.14 11.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Heme_oxygenase PF01126.20 OAJ32344.1 - 4.7e-08 33.1 0.0 4.6e-06 26.6 0.0 2.9 3 1 0 3 3 3 2 Heme oxygenase Ribosomal_S26e PF01283.19 OAJ32345.1 - 1.9e-53 179.5 9.1 2.4e-53 179.1 9.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 OAJ32345.1 - 0.0057 17.2 1.6 0.016 15.8 1.5 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 OAJ32345.1 - 0.012 16.6 0.8 0.026 15.5 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 OAJ32345.1 - 0.14 12.3 2.4 0.56 10.4 2.6 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 OAJ32345.1 - 0.17 11.8 0.8 0.17 11.8 0.8 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain MFS_1 PF07690.16 OAJ32348.1 - 1.9e-08 33.7 21.9 1.9e-08 33.7 21.9 3.5 2 2 0 2 2 2 1 Major Facilitator Superfamily PSRT PF07636.11 OAJ32348.1 - 0.13 11.9 5.1 0.37 10.5 5.1 1.7 1 0 0 1 1 1 0 PSRT adh_short PF00106.25 OAJ32349.1 - 5.4e-23 81.5 0.0 1.4e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 OAJ32349.1 - 1.9e-18 66.9 0.0 3.3e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 OAJ32349.1 - 6.4e-07 29.5 0.0 9.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 OAJ32349.1 - 0.0093 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 OAJ32349.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 OAJ32349.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAM165 PF14981.6 OAJ32349.1 - 0.023 14.5 0.9 0.04 13.7 0.9 1.3 1 0 0 1 1 1 0 FAM165 family TFIIB PF00382.19 OAJ32349.1 - 0.048 13.7 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Transcription factor TFIIB repeat 2-Hacid_dh_C PF02826.19 OAJ32349.1 - 0.055 12.8 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HR1 PF02185.16 OAJ32349.1 - 0.085 13.0 1.2 0.15 12.2 1.2 1.4 1 0 0 1 1 1 0 Hr1 repeat NAD_binding_7 PF13241.6 OAJ32349.1 - 0.18 12.3 0.1 0.3 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pro_isomerase PF00160.21 OAJ32350.1 - 5e-48 163.3 0.1 1.6e-47 161.7 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 OAJ32350.1 - 8.5e-11 42.2 1.3 0.00097 19.9 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ32350.1 - 0.00084 19.6 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ32350.1 - 0.033 13.1 0.8 0.86 8.5 0.1 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Prefoldin_2 PF01920.20 OAJ32351.1 - 4.3e-17 62.0 7.9 5.5e-17 61.7 7.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 OAJ32351.1 - 0.014 15.6 1.4 0.014 15.6 1.4 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF2408 PF10303.9 OAJ32351.1 - 0.03 14.9 2.7 0.04 14.5 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Cortex-I_coil PF09304.10 OAJ32351.1 - 0.69 10.2 7.3 0.22 11.8 1.1 2.2 1 1 0 2 2 2 0 Cortexillin I, coiled coil Coat_F PF07875.12 OAJ32351.1 - 1 9.7 4.2 8.1 6.8 0.3 2.7 2 1 1 3 3 3 0 Coat F domain Cep57_MT_bd PF06657.13 OAJ32351.1 - 1.7 9.2 8.6 11 6.6 0.4 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FlxA PF14282.6 OAJ32351.1 - 3.1 7.8 11.9 1.7 8.7 0.3 2.3 2 0 0 2 2 2 0 FlxA-like protein Asp PF00026.23 OAJ32352.1 - 9.9e-41 140.2 0.0 2.2e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ32352.1 - 1.5e-06 28.6 2.2 0.00072 19.8 0.3 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 OAJ32352.1 - 0.025 15.2 0.1 11 6.8 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Abhydrolase_1 PF00561.20 OAJ32353.1 - 1.3e-29 103.6 0.0 2.6e-29 102.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 OAJ32353.1 - 1.2e-11 44.3 0.0 1.1e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ32353.1 - 2.6e-10 41.3 1.7 2.6e-10 41.3 1.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 OAJ32353.1 - 0.0093 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 OAJ32353.1 - 0.27 10.0 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AAA PF00004.29 OAJ32354.1 - 5.1e-44 149.9 0.1 1.2e-43 148.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 OAJ32354.1 - 4e-09 36.3 0.6 1.8e-08 34.2 0.0 2.3 3 0 0 3 3 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 OAJ32354.1 - 1.8e-08 34.5 0.0 1.1e-07 31.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 OAJ32354.1 - 1.3e-07 32.2 0.2 4.6e-05 23.9 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 OAJ32354.1 - 2.4e-07 31.0 0.1 6.4e-07 29.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 OAJ32354.1 - 3.8e-06 26.6 0.1 9.4e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 OAJ32354.1 - 8.1e-06 25.2 0.0 3.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 OAJ32354.1 - 8.1e-05 22.9 0.6 0.014 15.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ32354.1 - 0.00035 20.3 0.0 0.00086 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 OAJ32354.1 - 0.00086 19.1 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 OAJ32354.1 - 0.00086 19.9 0.0 0.0044 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 OAJ32354.1 - 0.00089 19.5 0.1 0.0026 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 OAJ32354.1 - 0.0012 18.8 0.1 0.0028 17.6 0.0 1.7 2 0 0 2 2 1 1 NTPase TIP49 PF06068.13 OAJ32354.1 - 0.0024 17.1 0.0 0.0059 15.9 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 OAJ32354.1 - 0.0029 17.6 0.0 0.0066 16.4 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 OAJ32354.1 - 0.005 17.0 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 OAJ32354.1 - 0.0056 16.2 0.1 0.031 13.8 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 OAJ32354.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 1 1 RNA helicase Mg_chelatase PF01078.21 OAJ32354.1 - 0.0082 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 OAJ32354.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 OAJ32354.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 OAJ32354.1 - 0.02 14.8 0.1 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 OAJ32354.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TniB PF05621.11 OAJ32354.1 - 0.021 14.2 0.0 0.83 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 OAJ32354.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 OAJ32354.1 - 0.038 13.9 0.8 0.54 10.1 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prot_ATP_OB_N PF17758.1 OAJ32354.1 - 0.041 13.5 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Bac_DnaA PF00308.18 OAJ32354.1 - 0.061 13.2 0.0 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.6 OAJ32354.1 - 0.061 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 OAJ32354.1 - 0.066 12.3 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 OAJ32354.1 - 0.078 12.5 0.5 0.28 10.7 0.5 1.8 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 OAJ32354.1 - 0.088 11.7 0.1 0.25 10.2 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.6 OAJ32354.1 - 0.12 12.9 1.0 0.64 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 OAJ32354.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 OAJ32354.1 - 0.19 11.4 0.3 1.8 8.2 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain DNA_pol3_tau_4 PF12168.8 OAJ32356.1 - 2 9.0 7.0 0.29 11.7 2.2 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Ribosomal_60s PF00428.19 OAJ32357.1 - 0.023 15.2 3.2 0.051 14.2 3.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SWIRM-assoc_2 PF16496.5 OAJ32357.1 - 2.7 6.8 9.2 3.5 6.4 9.2 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-C3HC4_2 PF13923.6 OAJ32358.1 - 5.6e-08 32.5 13.6 9e-08 31.8 13.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ32358.1 - 4.4e-07 30.1 13.3 7.1e-07 29.5 13.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ32358.1 - 3e-06 27.0 13.0 5e-06 26.3 13.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 OAJ32358.1 - 7.5e-06 25.7 14.4 1.1e-05 25.2 14.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 OAJ32358.1 - 0.0002 21.2 13.5 0.00035 20.5 13.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Taxilin PF09728.9 OAJ32358.1 - 0.006 15.8 0.4 0.0096 15.1 0.4 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein zf-rbx1 PF12678.7 OAJ32358.1 - 0.0063 16.8 11.2 0.014 15.7 11.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3450 PF11932.8 OAJ32358.1 - 0.0067 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) zf-RING_UBOX PF13445.6 OAJ32358.1 - 0.0082 16.1 10.9 0.016 15.3 10.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 OAJ32358.1 - 0.015 15.4 12.4 0.028 14.6 12.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 OAJ32358.1 - 0.028 14.5 5.4 0.051 13.7 5.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 TolA_bind_tri PF16331.5 OAJ32358.1 - 0.038 14.1 0.2 0.074 13.1 0.2 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Prok-RING_4 PF14447.6 OAJ32358.1 - 0.038 13.9 12.8 0.08 12.8 12.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 YlqD PF11068.8 OAJ32358.1 - 0.076 13.4 1.8 0.15 12.5 1.8 1.4 1 0 0 1 1 1 0 YlqD protein TMF_DNA_bd PF12329.8 OAJ32358.1 - 0.087 12.8 2.1 0.16 12.0 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 OAJ32358.1 - 0.16 10.8 1.4 0.25 10.2 1.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 OAJ32358.1 - 0.29 11.4 0.4 0.55 10.5 0.4 1.5 1 0 0 1 1 1 0 Haemolysin XhlA zf-RING_6 PF14835.6 OAJ32358.1 - 2 8.4 9.0 3.3 7.6 9.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 OAJ32358.1 - 5.2 6.9 12.7 8.8 6.2 12.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Macoilin PF09726.9 OAJ32358.1 - 7.9 4.9 15.2 12 4.3 15.2 1.2 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 OAJ32359.1 - 1.5e-11 44.6 5.3 0.041 14.8 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 OAJ32359.1 - 0.073 11.7 0.6 0.41 9.2 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1241 PF06840.11 OAJ32359.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Pro_isomerase PF00160.21 OAJ32360.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 OAJ32360.1 - 0.00034 20.5 5.6 0.28 11.4 0.7 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ32360.1 - 0.56 10.1 2.7 9.2 6.3 0.3 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Secretin_N PF03958.17 OAJ32361.1 - 0.26 11.7 2.0 0.84 10.1 0.3 2.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain PIRT PF15099.6 OAJ32362.1 - 0.2 11.3 0.0 0.2 11.3 0.0 2.3 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family TMEM154 PF15102.6 OAJ32362.1 - 0.61 10.0 2.2 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family COG4 PF08318.12 OAJ32364.1 - 9.5e-73 245.2 0.0 3.4e-72 243.3 0.0 1.8 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 OAJ32364.1 - 0.16 10.8 0.0 0.3 9.9 0.0 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Ras PF00071.22 OAJ32365.1 - 1.3e-64 216.7 0.8 1.5e-64 216.5 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ32365.1 - 5e-36 123.5 0.1 7.9e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ32365.1 - 2.3e-17 63.0 0.1 2.9e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 OAJ32365.1 - 4e-06 26.8 1.0 0.042 13.7 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 OAJ32365.1 - 6.4e-06 25.7 0.1 7.6e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ32365.1 - 1.1e-05 25.1 0.3 2.8e-05 23.7 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 OAJ32365.1 - 5e-05 23.3 0.0 7.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 OAJ32365.1 - 9.2e-05 21.9 0.1 0.00012 21.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 OAJ32365.1 - 0.0027 17.2 0.1 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 OAJ32365.1 - 0.0087 16.5 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 OAJ32365.1 - 0.0093 16.4 0.1 0.53 10.7 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 OAJ32365.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 OAJ32365.1 - 0.05 13.6 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 OAJ32365.1 - 0.058 13.7 0.0 0.086 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 OAJ32365.1 - 0.078 12.4 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 OAJ32365.1 - 0.08 12.4 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AIRC PF00731.20 OAJ32365.1 - 0.091 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 AIR carboxylase PduV-EutP PF10662.9 OAJ32365.1 - 0.093 12.5 0.0 1.5 8.6 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 OAJ32365.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 OAJ32365.1 - 0.17 11.5 0.0 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 OAJ32366.1 - 4.9e-45 153.7 0.0 6.1e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 OAJ32366.1 - 8.7e-11 42.8 0.0 1.1e-10 42.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 OAJ32366.1 - 8.5e-10 38.7 1.1 9.4e-08 32.0 0.5 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 OAJ32366.1 - 0.00012 21.7 0.1 0.071 12.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 OAJ32366.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 OAJ32366.1 - 0.0098 15.2 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) AXE1 PF05448.12 OAJ32366.1 - 0.014 14.1 0.2 0.13 11.0 0.0 2.2 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) LCAT PF02450.15 OAJ32366.1 - 0.032 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 OAJ32366.1 - 0.19 11.5 0.0 0.46 10.3 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 OAJ32367.1 - 4.3e-22 78.5 45.4 4.2e-12 45.7 29.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 OAJ32367.1 - 4.2 5.5 10.5 14 3.8 5.3 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Rep_fac-A_3 PF08661.11 OAJ32368.1 - 2.2e-26 92.2 0.2 2.4e-26 92.1 0.2 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 PIF3 PF05006.12 OAJ32368.1 - 0.058 13.5 0.0 0.069 13.2 0.0 1.0 1 0 0 1 1 1 0 Per os infectivity factor 3 Homeodomain PF00046.29 OAJ32369.1 - 7.6e-19 67.3 1.6 1.1e-18 66.7 1.6 1.3 1 0 0 1 1 1 1 Homeodomain CD34_antigen PF06365.12 OAJ32369.1 - 1.3 8.5 3.1 2 7.9 3.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family API5 PF05918.11 OAJ32369.1 - 1.8 7.3 9.7 2.6 6.8 9.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cyto_heme_lyase PF01265.17 OAJ32370.1 - 1.1e-41 143.4 1.9 4e-39 135.0 0.2 2.3 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase PX PF00787.24 OAJ32371.1 - 4.5e-22 78.2 0.5 1.1e-21 76.9 0.5 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 OAJ32371.1 - 2.7e-07 30.4 7.4 1.1e-05 25.1 0.7 2.6 3 0 0 3 3 3 2 Vps5 C terminal like ANAPC2 PF08672.11 OAJ32371.1 - 0.045 14.2 1.0 5.6 7.5 0.1 3.1 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 tRNA-synt_1c PF00749.21 OAJ32372.1 - 7.3e-106 353.6 0.4 1.1e-105 353.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 OAJ32372.1 - 2.3e-36 125.3 0.0 4.8e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 OAJ32372.1 - 3e-29 102.1 0.1 1e-28 100.4 0.0 2.0 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 OAJ32372.1 - 9e-08 32.9 6.2 9e-08 32.9 6.2 2.5 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S5 PF00333.20 OAJ32373.1 - 1.5e-29 101.7 0.5 3.7e-29 100.5 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 OAJ32373.1 - 4.5e-23 80.5 0.1 7.5e-23 79.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 OAJ32373.1 - 3.9 8.1 8.4 8.4 7.0 8.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-ANAPC11 PF12861.7 OAJ32374.1 - 6e-31 106.4 9.1 7.7e-31 106.0 9.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 OAJ32374.1 - 2.7e-19 69.2 14.0 3.9e-19 68.7 14.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 OAJ32374.1 - 1.1e-06 28.9 14.5 1.1e-05 25.6 14.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ32374.1 - 2.1e-05 24.3 11.5 7.9e-05 22.5 11.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ32374.1 - 0.011 15.6 17.7 0.16 11.8 17.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 OAJ32374.1 - 0.78 9.5 13.8 14 5.5 13.8 2.3 1 1 0 1 1 1 0 RING-like zinc finger zf-HC5HC2H_2 PF13832.6 OAJ32374.1 - 1.1 9.5 10.4 0.28 11.3 7.6 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain TAFII28 PF04719.14 OAJ32375.1 - 6e-29 100.0 0.0 8.2e-29 99.5 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF4770 PF15994.5 OAJ32375.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Arrestin_C PF02752.22 OAJ32376.1 - 9.3e-15 55.3 0.0 4.2e-13 49.9 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 OAJ32376.1 - 1.6e-06 28.3 0.0 0.00018 21.6 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain SKIP_SNW PF02731.15 OAJ32377.1 - 3.4e-70 234.8 1.3 3.4e-70 234.8 1.3 1.9 2 0 0 2 2 2 1 SKIP/SNW domain POT1PC PF16686.5 OAJ32378.1 - 2e-16 60.2 0.1 5.7e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 OAJ32378.1 - 3.5e-10 39.9 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 REPA_OB_2 PF16900.5 OAJ32378.1 - 0.044 13.7 0.0 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 Replication protein A OB domain DZR PF12773.7 OAJ32378.1 - 0.074 13.1 0.4 0.15 12.1 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 OAJ32378.1 - 0.62 9.9 2.9 1.2 9.0 2.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RFX_DNA_binding PF02257.15 OAJ32379.1 - 1.2e-18 67.5 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 RFX DNA-binding domain TPR_1 PF00515.28 OAJ32380.1 - 6e-19 67.0 0.1 4.8e-05 23.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32380.1 - 1.4e-14 52.9 1.3 0.00075 19.4 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ32380.1 - 1.5e-13 50.2 0.4 0.036 13.8 0.0 4.9 4 1 1 5 5 5 4 TPR repeat TPR_14 PF13428.6 OAJ32380.1 - 3.1e-12 46.2 3.4 0.035 14.9 0.0 6.4 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32380.1 - 8.6e-12 44.3 0.2 0.0034 17.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ32380.1 - 1.9e-09 36.9 0.0 0.052 13.6 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ32380.1 - 4.5e-09 36.1 4.6 0.028 14.8 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ32380.1 - 6.2e-07 29.8 3.0 0.11 13.0 0.0 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ32380.1 - 1.1e-06 28.9 0.9 0.0022 18.3 0.0 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ32380.1 - 0.00016 21.7 7.0 0.74 10.0 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ32380.1 - 0.0029 18.2 19.1 0.15 12.8 0.4 5.7 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 OAJ32380.1 - 0.0036 17.1 0.2 0.14 12.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 OAJ32380.1 - 0.21 11.9 10.7 0.17 12.2 0.4 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.6 OAJ32381.1 - 1.3e-13 51.6 0.0 1.7e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.15 OAJ32381.1 - 0.24 11.2 0.0 0.37 10.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase ATP11 PF06644.11 OAJ32382.1 - 2.3e-70 237.5 0.1 2.3e-70 237.5 0.1 1.5 2 0 0 2 2 2 1 ATP11 protein PepSY_2 PF13670.6 OAJ32382.1 - 1.9 8.6 5.8 0.94 9.5 1.5 2.5 1 1 2 3 3 3 0 Peptidase propeptide and YPEB domain Sel1 PF08238.12 OAJ32384.1 - 2.1e-15 56.8 19.4 0.013 16.1 0.2 8.4 8 0 0 8 8 8 6 Sel1 repeat TPR_1 PF00515.28 OAJ32384.1 - 0.0087 15.8 3.6 0.26 11.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32384.1 - 0.098 12.8 0.0 0.098 12.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32384.1 - 0.2 12.0 0.0 0.2 12.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ32384.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M14 PF00246.24 OAJ32385.1 - 2.5e-57 194.9 0.0 9.7e-56 189.7 0.0 2.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Ribosom_S12_S23 PF00164.25 OAJ32386.1 - 7.8e-48 160.8 0.6 9.9e-48 160.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L27e PF01777.18 OAJ32387.1 - 4.5e-38 129.5 1.6 7.2e-38 128.8 1.6 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 OAJ32387.1 - 0.00018 21.3 0.7 0.00041 20.2 0.7 1.6 1 0 0 1 1 1 1 KOW motif Iso_dh PF00180.20 OAJ32388.1 - 4.1e-115 384.6 0.0 4.7e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase YebG PF07130.12 OAJ32388.1 - 0.068 13.0 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 YebG protein DUF2034 PF10356.9 OAJ32389.1 - 2.2e-14 53.3 4.1 1.6e-13 50.5 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 OAJ32389.1 - 3.6e-06 27.0 0.0 9.4e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease MSA_2 PF00985.17 OAJ32389.1 - 0.016 15.6 1.9 0.016 15.6 1.9 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Diphtheria_T PF02764.14 OAJ32389.1 - 0.52 10.3 1.5 0.87 9.6 1.5 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Ndc1_Nup PF09531.10 OAJ32389.1 - 0.98 8.0 5.3 1.1 7.9 5.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AT_hook PF02178.19 OAJ32389.1 - 1.1 9.4 18.1 0.28 11.2 1.5 4.1 3 0 0 3 3 3 0 AT hook motif Euplotes_phero PF05842.11 OAJ32389.1 - 2.5 8.7 7.6 4.8 7.8 7.6 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein CitMHS PF03600.16 OAJ32391.1 - 1.3 8.1 6.3 3.2 6.8 6.4 1.6 1 1 0 1 1 1 0 Citrate transporter Cmc1 PF08583.10 OAJ32393.1 - 4.2e-11 42.7 1.6 5.6e-11 42.3 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like F-box-like PF12937.7 OAJ32394.1 - 0.0022 17.9 0.3 0.0049 16.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like Pyr_redox_2 PF07992.14 OAJ32395.1 - 1.4e-39 136.1 0.0 1.1e-25 90.5 0.0 3.3 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ32395.1 - 4.5e-13 49.6 0.1 9.5e-08 32.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 OAJ32395.1 - 0.0051 17.0 0.0 7.3 6.9 0.0 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 OAJ32395.1 - 0.0063 15.8 0.0 14 4.8 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 OAJ32395.1 - 0.0073 16.7 0.0 0.4 11.2 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding TrkA_N PF02254.18 OAJ32395.1 - 0.01 16.1 0.0 5 7.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 OAJ32395.1 - 0.015 14.4 0.0 2.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 OAJ32395.1 - 0.037 13.1 0.2 1.6 7.7 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain ACPS PF01648.20 OAJ32396.1 - 2.3e-09 37.4 0.0 7.4e-09 35.7 0.0 1.8 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Myc_N PF01056.18 OAJ32398.1 - 0.37 10.6 3.7 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region TFIIE-A_C PF11521.8 OAJ32398.1 - 0.81 10.0 12.9 0.24 11.7 0.4 2.9 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Dak1 PF02733.17 OAJ32400.1 - 1.2e-81 274.1 0.1 1.8e-81 273.5 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 OAJ32400.1 - 7.9e-38 130.1 4.6 1.8e-37 128.9 4.6 1.6 1 0 0 1 1 1 1 DAK2 domain DOT1 PF08123.13 OAJ32400.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 GPI-anchored PF10342.9 OAJ32401.1 - 8.7e-12 45.6 0.1 1.7e-11 44.7 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKN1 PF03935.15 OAJ32402.1 - 2.5e-176 587.0 0.0 3.3e-176 586.6 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 OAJ32402.1 - 0.035 13.6 0.0 0.54 9.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 16 Peptidase_S28 PF05577.12 OAJ32403.1 - 2.7e-38 131.9 0.5 2.4e-33 115.6 0.0 2.9 3 0 0 3 3 3 2 Serine carboxypeptidase S28 Rnk_N PF14760.6 OAJ32403.1 - 0.23 12.0 0.3 0.56 10.7 0.3 1.7 1 0 0 1 1 1 0 Rnk N-terminus SRP54 PF00448.22 OAJ32404.1 - 1.7e-45 155.1 0.0 2e-28 99.4 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 OAJ32404.1 - 5.9e-45 154.4 0.0 1.1e-44 153.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 OAJ32404.1 - 5.3e-08 33.0 0.0 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 OAJ32404.1 - 0.0065 15.5 0.0 0.063 12.2 0.0 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 OAJ32404.1 - 0.008 16.2 0.0 0.039 14.0 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 OAJ32404.1 - 0.045 14.1 2.6 0.31 11.4 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain Fer4_NifH PF00142.18 OAJ32404.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 OAJ32404.1 - 0.089 12.7 0.0 0.44 10.4 0.0 2.0 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 OAJ32404.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 OAJ32404.1 - 0.15 12.4 0.0 0.64 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.15 OAJ32404.1 - 0.15 11.2 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Anion-transporting ATPase T3SS_needle_reg PF09025.10 OAJ32404.1 - 0.23 11.4 1.5 1.6 8.7 0.1 2.6 3 0 0 3 3 3 0 YopR, type III needle-polymerisation regulator MMR_HSR1 PF01926.23 OAJ32404.1 - 0.33 11.0 1.6 3 8.0 0.5 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase START PF01852.19 OAJ32405.1 - 9.2e-05 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 START domain Q_salvage PF10343.9 OAJ32406.1 - 2.3e-10 40.5 0.0 2.4e-07 30.6 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family CGI-121 PF08617.10 OAJ32407.1 - 8.8e-36 123.5 0.0 1.1e-35 123.2 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 RCC1 PF00415.18 OAJ32408.1 - 2.3e-06 28.1 0.5 12 6.6 0.0 6.2 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 OAJ32408.1 - 0.00026 20.7 12.4 0.11 12.3 1.1 5.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 OAJ32408.1 - 0.0035 17.2 0.2 0.0094 15.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ32408.1 - 0.099 12.5 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain AMP-binding PF00501.28 OAJ32409.1 - 1.1e-87 294.4 0.0 1.6e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ32409.1 - 3.6e-08 34.3 0.2 8.2e-08 33.1 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RPN7 PF10602.9 OAJ32410.1 - 3.4e-39 134.3 0.0 7.8e-39 133.2 0.0 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 OAJ32410.1 - 1.2e-12 48.2 0.0 2.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF1242 PF06842.12 OAJ32411.1 - 1.1e-18 66.7 2.1 1.5e-18 66.3 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.6 OAJ32411.1 - 0.083 13.2 0.4 0.12 12.7 0.4 1.3 1 0 0 1 1 1 0 Jag N-terminus LST1 PF05083.13 OAJ32411.1 - 0.14 12.4 0.1 0.53 10.6 0.1 1.7 2 0 0 2 2 2 0 LST-1 protein TPR_1 PF00515.28 OAJ32412.1 - 1.5e-13 50.0 1.0 0.0021 17.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32412.1 - 4.1e-11 42.1 1.3 0.0076 16.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ32412.1 - 1.5e-07 31.8 0.3 6.1e-05 23.5 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ32412.1 - 6.9e-07 29.4 0.4 1e-06 28.9 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 OAJ32412.1 - 0.00011 22.8 0.3 0.057 14.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ32412.1 - 0.0015 18.2 0.2 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 OAJ32412.1 - 0.0019 18.1 0.3 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ32412.1 - 0.0048 17.2 0.7 2 8.8 0.0 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ32412.1 - 0.0062 17.3 3.8 0.51 11.3 2.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32412.1 - 0.014 15.6 1.2 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HHH_8 PF14716.6 OAJ32412.1 - 0.033 14.6 0.6 5.3 7.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain TPR_17 PF13431.6 OAJ32412.1 - 0.075 13.5 0.8 1.8 9.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ32412.1 - 0.11 13.2 1.9 23 5.9 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MmgE_PrpD PF03972.14 OAJ32413.1 - 4.8e-95 318.7 4.5 4.9e-53 180.2 0.2 2.1 1 1 1 2 2 2 2 MmgE/PrpD family RELT PF12606.8 OAJ32414.1 - 1.1 8.3 5.0 42 3.2 5.0 2.3 1 1 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 HSP70 PF00012.20 OAJ32415.1 - 9e-21 73.7 1.4 9.7e-21 73.6 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein ASF1_hist_chap PF04729.13 OAJ32415.1 - 2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone SSF PF00474.17 OAJ32416.1 - 1.4e-12 47.3 25.3 5.4e-12 45.3 25.3 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Ribosomal_S19 PF00203.21 OAJ32417.1 - 2.2e-26 91.5 0.0 2.7e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 ChAPs PF09295.10 OAJ32418.1 - 1.5e-151 505.0 0.0 3.1e-151 503.9 0.0 1.5 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 OAJ32418.1 - 0.00014 22.3 0.0 1.5 9.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32418.1 - 0.013 15.6 0.3 6.2 7.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 OAJ32418.1 - 0.017 15.3 2.6 4.4 7.6 0.1 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 OAJ32419.1 - 3e-56 190.7 0.0 4.1e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32419.1 - 1.5e-28 99.8 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 OAJ32419.1 - 4.8e-06 26.1 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 OAJ32419.1 - 0.038 13.9 0.1 3.1 7.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 OAJ32419.1 - 0.057 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 OAJ32419.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SET PF00856.28 OAJ32420.1 - 9.9e-19 68.3 0.0 5.4e-18 66.0 0.0 2.4 1 0 0 1 1 1 1 SET domain N-SET PF11764.8 OAJ32420.1 - 4.3e-12 46.5 6.8 1.8e-05 24.9 0.2 3.7 2 1 1 3 3 3 2 COMPASS (Complex proteins associated with Set1p) component N BUD22 PF09073.10 OAJ32420.1 - 0.026 13.9 14.0 0.087 12.1 14.0 1.9 1 0 0 1 1 1 0 BUD22 ProRS-C_1 PF09180.11 OAJ32421.1 - 1e-27 96.1 1.8 2e-27 95.2 1.8 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 OAJ32421.1 - 2.4e-16 59.6 0.0 4.9e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 OAJ32421.1 - 6.9e-16 58.7 0.0 1.9e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Zn-ribbon_8 PF09723.10 OAJ32421.1 - 0.23 11.6 1.8 0.97 9.6 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain EzrA PF06160.12 OAJ32421.1 - 0.49 8.5 1.5 0.43 8.7 0.2 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SNF2_N PF00176.23 OAJ32422.1 - 2.9e-57 194.0 0.1 4.5e-57 193.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 OAJ32422.1 - 1.1e-16 61.1 0.0 4.2e-16 59.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ32422.1 - 3.9e-09 36.8 0.0 9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 OAJ32422.1 - 6.2e-07 28.9 1.8 6.3e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UBA PF00627.31 OAJ32422.1 - 9.6e-05 22.2 0.1 0.00024 20.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HDA2-3 PF11496.8 OAJ32422.1 - 0.016 14.4 0.2 3.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 TrwB_AAD_bind PF10412.9 OAJ32422.1 - 0.54 9.1 4.6 0.28 10.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UCH PF00443.29 OAJ32423.1 - 4.1e-36 124.8 0.0 1.8e-31 109.6 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 OAJ32423.1 - 3.3e-05 23.6 0.0 0.53 9.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase MCM3AP_GANP PF16769.5 OAJ32423.1 - 0.25 9.5 0.7 1.2 7.2 0.1 2.0 2 0 0 2 2 2 0 MCM3AP domain of GANP CSRNP_N PF16019.5 OAJ32423.1 - 0.35 10.8 3.5 1.6 8.6 3.5 2.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus HORMA PF02301.18 OAJ32424.1 - 1.1e-07 31.6 0.0 2.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 HORMA domain Sod_Fe_C PF02777.18 OAJ32425.1 - 6.3e-34 116.2 1.4 9.2e-34 115.7 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 OAJ32425.1 - 7.6e-32 109.6 5.1 1.6e-31 108.6 5.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.6 OAJ32425.1 - 0.05 13.1 0.0 0.21 11.0 0.0 1.9 1 1 1 2 2 2 0 AsmA-like C-terminal region Vps54 PF07928.12 OAJ32427.1 - 1.6e-52 177.5 1.6 1.6e-52 177.5 1.6 2.6 2 0 0 2 2 2 1 Vps54-like protein TFIIA PF03153.13 OAJ32427.1 - 0.00016 21.8 43.6 0.00016 21.8 43.6 2.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Vps54_N PF10475.9 OAJ32427.1 - 0.00039 19.8 2.0 0.00039 19.8 2.0 2.2 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF4667 PF15700.5 OAJ32427.1 - 0.0015 18.7 2.3 0.0015 18.7 2.3 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4667) RBM39linker PF15519.6 OAJ32427.1 - 4 8.6 12.2 61 4.8 12.2 3.3 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Mcm10 PF09332.11 OAJ32427.1 - 6.6 6.0 26.4 30 3.9 26.4 2.1 1 0 0 1 1 1 0 Mcm10 replication factor Inhibitor_I71 PF12628.7 OAJ32427.1 - 9.7 6.0 6.1 4.1e+02 0.7 0.0 2.5 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor MRG PF05712.13 OAJ32430.1 - 3.1e-59 199.6 0.0 4.8e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 OAJ32430.1 - 1.7e-10 40.6 0.0 3.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MSA-2c PF12238.8 OAJ32430.1 - 0.00082 19.4 2.0 0.00082 19.4 2.0 3.3 3 0 0 3 3 3 1 Merozoite surface antigen 2c DUF2951 PF11166.8 OAJ32430.1 - 0.53 10.5 2.1 1 9.6 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) RVT_1 PF00078.27 OAJ32431.1 - 1.6e-12 47.4 0.0 3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 OAJ32431.1 - 0.082 12.7 0.5 0.24 11.2 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase-like Cauli_VI PF01693.16 OAJ32432.1 - 0.00071 19.8 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF2457 PF10446.9 OAJ32433.1 - 0.099 11.8 7.1 0.096 11.8 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 OAJ32433.1 - 0.63 10.5 12.0 0.73 10.3 12.0 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 OAJ32433.1 - 2.4 7.8 9.3 2.8 7.6 9.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 OAJ32433.1 - 7 5.9 9.6 7.7 5.7 9.6 1.0 1 0 0 1 1 1 0 NOA36 protein Ank_4 PF13637.6 OAJ32434.1 - 5.8e-30 103.3 0.3 1.1e-13 51.4 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 OAJ32434.1 - 4.1e-28 97.8 0.0 1.2e-15 57.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ32434.1 - 5.1e-26 90.4 0.3 1.8e-09 37.6 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 OAJ32434.1 - 1.9e-24 85.0 0.3 5.9e-07 29.6 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 OAJ32434.1 - 5.8e-24 81.6 0.0 3.1e-06 27.1 0.0 5.6 7 0 0 7 7 7 4 Ankyrin repeat Cytochrom_C1 PF02167.15 OAJ32435.1 - 9.6e-100 332.8 0.0 1.2e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 OAJ32435.1 - 0.0021 18.3 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 OAJ32435.1 - 0.047 14.8 0.1 0.24 12.6 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c CAP_GLY PF01302.25 OAJ32436.1 - 1.9e-26 91.9 0.8 3.2e-26 91.1 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 OAJ32436.1 - 1e-11 45.1 0.0 3.7e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain HMA PF00403.26 OAJ32437.1 - 6.5e-18 64.9 0.7 7.5e-18 64.7 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain WD40 PF00400.32 OAJ32439.1 - 1.4e-21 76.4 20.2 0.00018 22.2 0.1 7.4 6 2 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ32439.1 - 4.4e-08 33.3 2.5 0.0096 16.2 0.1 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 OAJ32439.1 - 0.0001 21.4 0.0 1.4 7.8 0.0 3.9 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Rtf2 PF04641.12 OAJ32440.1 - 0.00016 21.1 0.1 0.00034 20.1 0.1 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 OAJ32440.1 - 0.0034 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Peptidase_M22 PF00814.25 OAJ32441.1 - 1.2e-66 225.2 0.1 1.6e-66 224.8 0.1 1.1 1 0 0 1 1 1 1 Glycoprotease family Adaptin_N PF01602.20 OAJ32442.1 - 1.2e-103 347.4 0.0 1.7e-103 347.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 OAJ32442.1 - 4.3e-51 173.0 0.0 8.1e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 OAJ32442.1 - 6.5e-28 97.2 0.0 4.4e-27 94.5 0.0 2.4 1 1 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 OAJ32442.1 - 1.8e-19 69.9 0.4 8e-10 39.0 0.0 5.3 2 1 5 7 7 7 4 HEAT repeats Cnd1 PF12717.7 OAJ32442.1 - 3.9e-07 30.3 2.7 0.086 12.9 0.0 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 OAJ32442.1 - 0.0013 18.9 6.3 1.2 9.6 0.1 5.9 7 0 0 7 7 7 1 HEAT repeat HEAT_PBS PF03130.16 OAJ32442.1 - 0.025 15.2 3.4 27 5.8 0.1 5.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat OmpW PF03922.14 OAJ32443.1 - 0.07 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 OmpW family Phosphoesterase PF04185.14 OAJ32444.1 - 5e-26 91.7 1.4 2.1e-25 89.7 1.4 1.8 1 1 0 1 1 1 1 Phosphoesterase family Gram_pos_anchor PF00746.21 OAJ32444.1 - 1.1 9.2 4.1 4.1 7.4 0.8 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DDE_3 PF13358.6 OAJ32445.1 - 2e-13 50.3 0.2 5.1e-13 49.0 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease AAA PF00004.29 OAJ32446.1 - 6.1e-18 65.5 0.0 3.6e-17 63.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 OAJ32446.1 - 8.9e-07 29.1 0.5 8.5e-06 25.9 0.2 2.4 2 1 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.6 OAJ32446.1 - 0.016 15.6 2.8 0.22 11.9 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.6 OAJ32446.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 OAJ32446.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 OAJ32446.1 - 0.16 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Secretin_N PF03958.17 OAJ32447.1 - 0.56 10.6 3.1 14 6.2 0.0 3.6 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain ADH_zinc_N PF00107.26 OAJ32448.1 - 1.8e-16 60.3 1.1 3.2e-16 59.5 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 OAJ32448.1 - 5.4e-10 40.4 0.2 1e-09 39.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 OAJ32448.1 - 0.0079 16.1 0.0 0.038 13.9 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Nucleoporin_C PF03177.14 OAJ32449.1 - 1.1e-77 262.2 3.9 1.5e-77 261.7 3.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 OAJ32449.1 - 3.5e-16 59.0 0.0 6.8e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 Nup133 N terminal like Talin_middle PF09141.10 OAJ32449.1 - 1.1 9.3 5.7 0.13 12.3 0.2 2.3 3 0 0 3 3 3 0 Talin, middle domain DUF1682 PF07946.14 OAJ32450.1 - 2.8e-62 210.8 0.0 3.2e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ank_2 PF12796.7 OAJ32451.1 - 1.8e-15 57.2 0.1 2.9e-11 43.8 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 OAJ32451.1 - 1e-13 51.5 1.7 1.2e-10 41.7 0.4 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ32451.1 - 4.5e-09 35.8 0.2 0.00062 20.0 0.1 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 OAJ32451.1 - 6.4e-08 32.7 1.8 0.00011 22.5 0.4 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 OAJ32451.1 - 3.5e-07 30.4 2.2 0.00024 21.3 0.3 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Nramp PF01566.18 OAJ32452.1 - 1.4e-87 294.0 29.5 5.1e-48 163.9 13.1 3.0 2 1 0 2 2 2 2 Natural resistance-associated macrophage protein Mito_fiss_reg PF05308.11 OAJ32453.1 - 0.2 11.7 6.6 0.26 11.3 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3835 PF12927.7 OAJ32454.1 - 1e-05 26.3 10.2 6.3e-05 23.8 0.0 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) DUF1192 PF06698.11 OAJ32455.1 - 0.067 13.2 0.1 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Zn_clus PF00172.18 OAJ32456.1 - 2.2e-06 27.7 7.2 3.7e-06 27.0 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DIE2_ALG10 PF04922.12 OAJ32457.1 - 1.4e-120 403.2 8.3 1.8e-119 399.6 8.3 2.0 1 1 0 1 1 1 1 DIE2/ALG10 family LexA_DNA_bind PF01726.16 OAJ32457.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain VRR_NUC PF08774.11 OAJ32458.1 - 6.9e-22 77.6 0.1 2.4e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 VRR-NUC domain LptE PF04390.12 OAJ32458.1 - 0.12 13.0 0.4 0.41 11.4 0.4 1.9 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Rho_N PF07498.12 OAJ32458.1 - 0.25 11.3 1.0 0.51 10.3 1.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cir_N PF10197.9 OAJ32458.1 - 0.44 10.8 8.4 0.033 14.4 1.7 2.7 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR SET PF00856.28 OAJ32459.1 - 1e-15 58.5 0.7 3.4e-15 56.8 0.0 2.3 3 0 0 3 3 3 1 SET domain Pre-SET PF05033.16 OAJ32459.1 - 2.5e-14 53.8 9.5 5.2e-14 52.8 6.6 2.3 2 0 0 2 2 2 1 Pre-SET motif preSET_CXC PF18264.1 OAJ32459.1 - 0.016 15.7 7.1 0.016 15.7 7.1 3.4 3 1 0 3 3 3 0 CXC domain YL1 PF05764.13 OAJ32460.1 - 2.7e-41 142.3 24.7 4.3e-41 141.6 24.7 1.3 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.11 OAJ32460.1 - 1.9e-09 37.1 0.0 3.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RBD-FIP PF09457.10 OAJ32460.1 - 7.6 6.5 6.3 2 8.4 0.8 2.4 2 0 0 2 2 2 0 FIP domain Peptidase_M19 PF01244.21 OAJ32461.1 - 1.2e-94 317.1 0.0 1.4e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Peptidase_M22 PF00814.25 OAJ32462.1 - 3.9e-74 249.7 0.0 1.4e-52 179.1 0.1 2.0 2 0 0 2 2 2 2 Glycoprotease family MOZ_SAS PF01853.18 OAJ32463.1 - 1.7e-75 252.6 0.0 2.3e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 OAJ32463.1 - 2.4e-20 71.9 2.1 2.4e-20 71.9 2.1 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain Ribosomal_60s PF00428.19 OAJ32463.1 - 0.016 15.8 0.4 0.016 15.8 0.4 4.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein HypA PF01155.19 OAJ32463.1 - 0.043 13.8 0.4 0.084 12.9 0.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 OAJ32463.1 - 3.3 7.8 6.6 0.38 10.8 0.2 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger MIF4G PF02854.19 OAJ32464.1 - 2.4e-52 177.7 0.1 2.6e-29 102.4 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 OAJ32464.1 - 1.2e-23 84.3 1.7 4e-23 82.7 0.3 2.7 1 1 1 2 2 2 1 Up-frameshift suppressor 2 Pes-10 PF07149.11 OAJ32464.1 - 0.0033 16.6 13.4 0.0077 15.3 13.4 1.6 1 0 0 1 1 1 1 Pes-10 Dor1 PF04124.12 OAJ32464.1 - 0.025 13.3 1.4 0.056 12.1 1.4 1.5 1 0 0 1 1 1 0 Dor1-like family CDC45 PF02724.14 OAJ32464.1 - 0.056 11.7 11.2 0.088 11.1 10.5 1.7 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 OAJ32464.1 - 0.51 8.4 29.6 1.2 7.1 29.6 1.6 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 OAJ32464.1 - 0.52 8.5 27.6 0.055 11.7 22.4 1.9 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 OAJ32464.1 - 3.5 6.9 23.7 0.018 14.5 14.5 1.8 2 0 0 2 2 2 0 SDA1 SOG2 PF10428.9 OAJ32465.1 - 2.2e-91 307.6 4.6 2.2e-91 307.6 4.6 4.1 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 OAJ32465.1 - 8e-14 51.2 10.5 2.2e-08 33.8 0.1 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 OAJ32465.1 - 1.5e-10 41.1 2.3 0.00021 21.6 0.0 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Perilipin PF03036.16 OAJ32465.1 - 0.017 14.2 2.6 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Perilipin family LRR_1 PF00560.33 OAJ32465.1 - 0.18 12.4 3.2 52 5.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat LrgB PF04172.16 OAJ32466.1 - 1.1e-36 126.4 9.2 2.9e-36 125.0 9.2 1.7 1 0 0 1 1 1 1 LrgB-like family LrgA PF03788.14 OAJ32466.1 - 0.0014 18.5 6.8 0.0045 16.9 0.5 4.0 2 2 1 3 3 3 1 LrgA family Gate PF07670.14 OAJ32466.1 - 3.1 8.1 6.9 0.6 10.4 2.5 2.4 2 1 0 2 2 2 0 Nucleoside recognition Pkr1 PF08636.10 OAJ32468.1 - 6.1e-25 87.1 1.1 7.5e-25 86.9 1.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MMR_HSR1_Xtn PF16897.5 OAJ32469.1 - 3.6e-41 139.5 0.2 7.3e-41 138.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 OAJ32469.1 - 1.9e-20 72.7 0.1 3.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 OAJ32469.1 - 3.9e-20 72.0 0.0 8.6e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 OAJ32469.1 - 6.7e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ32469.1 - 0.0016 18.5 0.2 0.065 13.3 0.0 2.4 1 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 OAJ32469.1 - 0.0035 17.7 0.6 0.17 12.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 OAJ32469.1 - 0.029 13.4 0.0 0.067 12.3 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain DUF1002 PF06207.11 OAJ32469.1 - 0.073 12.6 0.5 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) PWI PF01480.17 OAJ32470.1 - 1.2e-08 35.1 0.0 2.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 OAJ32470.1 - 4.6e-07 29.6 2.3 8e-07 28.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 OAJ32470.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 OAJ32470.1 - 0.00041 20.3 6.4 0.00076 19.5 6.4 1.5 1 0 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 OAJ32470.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 OAJ32470.1 - 0.034 14.8 0.2 0.034 14.8 0.2 2.0 2 0 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 OAJ32470.1 - 0.11 12.3 3.1 0.19 11.6 3.1 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger SUIM_assoc PF16619.5 OAJ32470.1 - 2.8 8.1 9.8 10 6.3 9.8 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LSM PF01423.22 OAJ32471.1 - 2.3e-22 78.5 0.1 2.6e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 OAJ32471.1 - 0.001 19.2 0.0 0.0013 18.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MFS_2 PF13347.6 OAJ32472.1 - 1.3e-10 40.4 1.4 1.3e-10 40.4 1.4 3.9 2 1 2 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.7 OAJ32472.1 - 0.0014 17.5 0.1 0.0034 16.3 0.1 1.6 1 0 0 1 1 1 1 MFS_1 like family DUF1980 PF09323.10 OAJ32472.1 - 0.0061 16.5 0.0 0.078 12.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1980) MFS_1 PF07690.16 OAJ32472.1 - 0.0088 15.0 41.0 0.0032 16.5 35.6 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 OAJ32472.1 - 0.037 12.2 0.4 0.082 11.1 0.4 1.5 1 0 0 1 1 1 0 BT1 family Nuc_sug_transp PF04142.15 OAJ32473.1 - 4.3e-06 26.1 0.2 6.8e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 OAJ32473.1 - 1.6e-05 24.4 4.9 9.9e-05 21.8 0.7 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 OAJ32473.1 - 0.00049 20.3 4.1 0.00049 20.3 4.1 3.2 3 1 0 3 3 3 2 EamA-like transporter family Asp PF00026.23 OAJ32474.1 - 2.5e-49 168.4 5.7 1.1e-48 166.3 5.7 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 OAJ32474.1 - 1.9e-06 28.2 3.6 0.055 13.7 0.0 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 OAJ32474.1 - 0.0031 17.3 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 OAJ32474.1 - 0.023 15.2 0.7 0.21 12.2 0.2 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 OAJ32474.1 - 0.031 14.9 1.6 0.56 10.9 0.9 2.6 2 0 0 2 2 2 0 Aspartyl protease DUF4497 PF14924.6 OAJ32474.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) OrsD PF12013.8 OAJ32475.1 - 8.7e-20 71.3 1.4 3.8e-11 43.4 0.2 4.3 4 0 0 4 4 4 2 Orsellinic acid/F9775 biosynthesis cluster protein D MPP6 PF10175.9 OAJ32475.1 - 6.5 7.3 17.3 1.3 9.6 0.1 3.5 3 0 0 3 3 3 0 M-phase phosphoprotein 6 zf_C2H2_ZHX PF18387.1 OAJ32475.1 - 8.8 6.1 13.5 31 4.3 0.0 3.7 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF89 PF01937.19 OAJ32476.1 - 1e-111 373.4 0.0 1.1e-111 373.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Response_reg PF00072.24 OAJ32477.1 - 1.9e-21 76.3 0.0 9.4e-16 58.0 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain E1_dh PF00676.20 OAJ32478.1 - 6e-107 357.0 0.3 7.7e-107 356.7 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 OAJ32478.1 - 0.00025 20.4 0.1 0.00048 19.4 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 OAJ32478.1 - 0.002 17.9 1.5 0.002 17.9 1.5 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain V-ATPase_H_N PF03224.14 OAJ32479.1 - 8.8e-81 271.6 0.0 2.9e-80 269.9 0.0 1.8 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 OAJ32479.1 - 6.8e-31 106.8 0.0 3.3e-30 104.6 0.0 2.3 1 1 0 1 1 1 1 V-ATPase subunit H HEAT PF02985.22 OAJ32479.1 - 0.0097 16.1 0.0 0.9 10.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeat ORC6 PF05460.13 OAJ32479.1 - 0.17 11.1 2.5 0.35 10.1 2.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ArgoN PF16486.5 OAJ32480.1 - 1.2e-14 55.1 0.0 6.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 OAJ32480.1 - 1.2e-11 44.1 0.4 2.6e-11 43.0 0.4 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain SMC_N PF02463.19 OAJ32481.1 - 7.3e-27 94.2 0.0 2.5e-26 92.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 OAJ32481.1 - 2.1e-14 54.5 10.2 2.1e-14 54.5 10.2 5.5 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 OAJ32481.1 - 8.8e-13 48.7 8.6 8.8e-13 48.7 8.6 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 OAJ32481.1 - 0.00021 21.2 9.0 0.053 13.3 0.4 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4527 PF15030.6 OAJ32481.1 - 0.00039 19.9 11.8 0.0049 16.3 0.7 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4527) AAA_29 PF13555.6 OAJ32481.1 - 0.0035 17.0 0.2 0.0085 15.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 OAJ32481.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.13 OAJ32481.1 - 0.021 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Fer4_NifH PF00142.18 OAJ32481.1 - 2.6 7.4 4.8 0.62 9.5 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APC_N_CC PF16689.5 OAJ32481.1 - 9.4 6.4 9.6 17 5.5 1.4 3.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Rpr2 PF04032.16 OAJ32482.1 - 4e-12 46.2 0.1 4e-12 46.2 0.1 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 OAJ32482.1 - 0.0051 16.8 0.9 0.0091 16.0 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon HLH PF00010.26 OAJ32483.1 - 0.00013 21.8 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain C2 PF00168.30 OAJ32485.1 - 1.5e-25 89.5 0.0 1.5e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain Flagellin_IN PF07196.13 OAJ32485.1 - 0.096 12.9 0.5 0.51 10.6 0.1 2.4 2 0 0 2 2 2 0 Flagellin hook IN motif zf-C3HC4_3 PF13920.6 OAJ32486.1 - 0.00062 19.6 2.8 0.0013 18.6 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ32486.1 - 0.00071 19.9 6.6 0.0012 19.1 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 OAJ32486.1 - 0.0028 17.5 5.2 0.0048 16.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 OAJ32487.1 - 7.6e-12 45.6 3.8 0.18 12.8 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat RhoGAP PF00620.27 OAJ32489.1 - 1.6e-38 131.9 0.0 3.7e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 OAJ32489.1 - 2.8e-14 53.7 0.0 1.2e-12 48.4 0.0 2.7 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 OAJ32489.1 - 4.4e-09 36.5 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.6 OAJ32489.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 OAJ32489.1 - 0.0024 18.4 0.0 0.36 11.4 0.0 2.4 2 0 0 2 2 2 1 PH domain RdgC PF04381.12 OAJ32489.1 - 0.093 12.0 0.3 0.2 10.9 0.3 1.5 1 0 0 1 1 1 0 Putative exonuclease, RdgC SPESP1 PF15754.5 OAJ32489.1 - 0.1 11.7 0.2 0.22 10.7 0.2 1.4 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Trypan_PARP PF05887.11 OAJ32489.1 - 0.94 9.5 11.6 0.18 11.8 7.3 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Tubulin PF00091.25 OAJ32490.1 - 1.6e-68 230.8 0.0 2.4e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 OAJ32490.1 - 7.4e-41 139.2 0.0 1.4e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 OAJ32490.1 - 0.00094 19.5 0.0 0.0025 18.1 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 OAJ32490.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain SHNi-TPR PF10516.9 OAJ32491.1 - 0.00035 19.9 0.8 0.00035 19.9 0.8 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_2 PF07719.17 OAJ32491.1 - 0.00055 19.9 7.7 0.39 10.9 1.2 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat Sigma70_ner PF04546.13 OAJ32491.1 - 0.0056 16.6 1.4 0.0056 16.6 1.4 2.6 3 0 0 3 3 3 1 Sigma-70, non-essential region YceD PF02620.17 OAJ32491.1 - 0.052 13.7 1.7 0.069 13.3 0.1 2.0 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD TPR_17 PF13431.6 OAJ32491.1 - 0.066 13.6 0.1 66 4.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ32491.1 - 0.092 12.6 4.1 6.7 6.7 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ32491.1 - 0.098 12.8 5.3 7.3 6.8 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 OAJ32491.1 - 0.38 8.8 6.6 0.64 8.0 6.6 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 OAJ32491.1 - 0.5 9.6 9.2 0.91 8.8 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein TPR_14 PF13428.6 OAJ32491.1 - 0.51 11.3 10.7 1.6 9.8 0.9 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat MSP1_C PF07462.11 OAJ32491.1 - 1.4 7.5 3.0 3 6.4 3.0 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TPR_12 PF13424.6 OAJ32491.1 - 1.4 9.2 12.8 1.1 9.6 0.7 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MULE PF10551.9 OAJ32493.1 - 1.4e-11 44.7 0.0 2.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 OAJ32493.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Transposase, Mutator family 4HBT_3 PF13622.6 OAJ32496.1 - 9.4e-30 104.7 0.6 1.4e-29 104.1 0.6 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MBOAT PF03062.19 OAJ32497.1 - 2.5e-38 132.3 17.9 1.6e-37 129.7 14.5 2.9 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family RVT_2 PF07727.14 OAJ32498.1 - 6.7e-72 242.0 0.0 9.4e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 OAJ32498.1 - 3.3e-15 56.3 0.0 1.2e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 OAJ32498.1 - 2.6e-05 24.0 0.3 5.8e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain Integrase_H2C2 PF17921.1 OAJ32498.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain DEC-1_N PF04625.13 OAJ32498.1 - 1.2 8.1 18.2 2.1 7.2 18.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Retrotran_gag_2 PF14223.6 OAJ32499.1 - 2.7e-05 23.9 0.0 4.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotrans_gag PF03732.17 OAJ32499.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.23 OAJ32499.1 - 0.24 11.5 2.2 0.51 10.5 2.2 1.6 1 0 0 1 1 1 0 Zinc knuckle FA_desaturase PF00487.24 OAJ32500.1 - 1.2e-22 81.0 18.9 1.3e-22 80.9 16.8 1.8 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 OAJ32500.1 - 4.7e-17 61.2 0.2 8.1e-17 60.4 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peroxidase_2 PF01328.17 OAJ32501.1 - 2.1e-24 87.1 0.0 2.5e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 GTP_EFTU PF00009.27 OAJ32502.1 - 3.4e-18 65.9 0.0 5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PRIMA1 PF16101.5 OAJ32503.1 - 3.1 7.8 14.3 0.32 11.0 3.8 2.7 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 DUF2975 PF11188.8 OAJ32503.1 - 7.9 6.4 17.3 2.4 8.0 0.9 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2975) zf-RING_UBOX PF13445.6 OAJ32505.1 - 1.9e-07 31.0 2.8 1.9e-07 31.0 2.8 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 OAJ32505.1 - 2.9e-06 27.0 4.4 2.9e-06 27.0 4.4 3.6 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 OAJ32505.1 - 1e-05 25.3 2.2 1e-05 25.3 2.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 OAJ32505.1 - 0.00016 21.7 4.8 0.00016 21.7 4.8 3.5 5 0 0 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 OAJ32505.1 - 0.00073 19.5 8.1 0.00073 19.5 8.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 OAJ32505.1 - 0.0047 16.8 7.6 0.0047 16.8 7.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ32505.1 - 0.37 11.1 20.9 0.076 13.4 12.0 3.2 2 1 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 OAJ32505.1 - 0.69 9.8 19.7 0.027 14.3 4.3 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 DEAD PF00270.29 OAJ32506.1 - 2e-38 131.9 0.1 3.8e-38 131.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 OAJ32506.1 - 6.7e-27 94.0 0.1 2.7e-25 88.9 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 OAJ32506.1 - 3.8e-07 30.3 0.0 8.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 OAJ32506.1 - 0.03 13.7 0.0 0.078 12.3 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Hexokinase_2 PF03727.16 OAJ32507.1 - 6.7e-80 268.0 0.0 9.7e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 OAJ32507.1 - 1.4e-66 224.2 0.0 2.2e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase ETF_QO PF05187.13 OAJ32509.1 - 1.7e-16 60.2 3.3 7e-07 29.3 0.0 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DUF3016 PF11454.8 OAJ32509.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DPBB_1 PF03330.18 OAJ32510.1 - 4e-06 27.0 0.2 6.2e-05 23.2 0.2 2.5 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 OAJ32510.1 - 0.0001 22.1 0.5 0.36 10.7 0.2 2.5 2 0 0 2 2 2 2 Barwin family Ank_2 PF12796.7 OAJ32511.1 - 0.0037 17.8 0.0 0.0074 16.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 OAJ32511.1 - 0.029 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 OAJ32511.1 - 0.044 14.4 0.1 0.086 13.4 0.1 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 OAJ32511.1 - 0.051 14.1 0.1 0.13 12.9 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 OAJ32511.1 - 0.11 13.0 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat E1-E2_ATPase PF00122.20 OAJ32512.1 - 3.2e-40 137.6 3.8 4.5e-38 130.6 0.1 3.4 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 OAJ32512.1 - 2.9e-17 63.7 0.3 6.7e-17 62.5 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 OAJ32512.1 - 1.2e-12 47.4 0.3 2.8e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 OAJ32512.1 - 0.002 17.9 0.1 0.0039 17.0 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 OAJ32512.1 - 0.033 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Ni_hydr_CYTB PF01292.20 OAJ32512.1 - 0.079 12.5 4.5 0.14 11.8 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 PsbI PF02532.14 OAJ32512.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.3 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Kinesin PF00225.23 OAJ32513.1 - 7.5e-103 343.9 0.0 2.7e-102 342.1 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 OAJ32513.1 - 2.6e-24 85.9 0.0 1.1e-23 83.8 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding Apolipoprotein PF01442.18 OAJ32513.1 - 0.002 18.1 6.8 0.002 18.1 6.8 4.7 1 1 4 5 5 5 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 OAJ32513.1 - 0.71 9.9 15.2 3.5 7.7 0.1 4.5 3 2 3 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus CS PF04969.16 OAJ32514.1 - 0.0004 21.4 0.2 0.00081 20.4 0.0 1.6 2 0 0 2 2 2 1 CS domain WD40 PF00400.32 OAJ32515.1 - 1.3e-25 89.1 12.8 7e-05 23.5 0.6 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF2415 PF10313.9 OAJ32515.1 - 0.0024 17.7 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) LRR_6 PF13516.6 OAJ32516.1 - 4e-13 48.3 13.5 0.13 12.4 0.1 9.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 OAJ32516.1 - 2.5e-09 37.2 12.2 0.51 10.8 0.6 6.8 2 1 8 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 OAJ32516.1 - 3.1e-08 33.1 0.0 3.3 8.6 0.0 7.7 10 0 0 10 10 8 1 Leucine Rich Repeat LRR_8 PF13855.6 OAJ32516.1 - 3.9e-07 29.7 10.0 0.6 9.9 0.0 7.0 6 2 1 7 7 7 3 Leucine rich repeat DARPP-32 PF05395.12 OAJ32516.1 - 0.12 12.5 6.7 0.18 12.0 6.7 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2457 PF10446.9 OAJ32516.1 - 0.3 10.2 21.1 0.44 9.6 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ATP11 PF06644.11 OAJ32516.1 - 0.48 10.2 2.2 0.65 9.7 2.2 1.2 1 0 0 1 1 1 0 ATP11 protein Nop14 PF04147.12 OAJ32516.1 - 0.56 8.4 15.6 0.7 8.0 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 OAJ32516.1 - 1.5 7.7 12.6 2.2 7.2 12.6 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.12 OAJ32516.1 - 1.8 7.9 16.4 2.5 7.4 16.4 1.1 1 0 0 1 1 1 0 SDA1 TMEM247 PF15444.6 OAJ32516.1 - 2.2 8.3 6.6 3.5 7.6 6.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 FAM176 PF14851.6 OAJ32516.1 - 3 7.5 8.2 5.2 6.7 8.2 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 OAJ32516.1 - 3.4 7.7 10.2 5.9 6.9 10.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 OAJ32516.1 - 3.8 5.5 23.2 5.2 5.0 23.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 OAJ32516.1 - 5.1 6.9 15.3 8.3 6.2 15.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pes-10 PF07149.11 OAJ32516.1 - 6 5.8 12.9 8.4 5.3 12.9 1.2 1 0 0 1 1 1 0 Pes-10 Pox_Ag35 PF03286.14 OAJ32516.1 - 6.4 6.5 10.9 10 5.8 10.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 OAJ32516.1 - 8.9 6.5 22.3 14 5.9 22.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 OAJ32516.1 - 9.4 6.7 21.8 23 5.5 21.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRN3 PF05327.11 OAJ32516.1 - 9.6 4.6 11.8 13 4.2 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Lipase_GDSL_2 PF13472.6 OAJ32518.1 - 0.055 13.9 0.2 0.21 12.0 0.0 2.1 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pex2_Pex12 PF04757.14 OAJ32519.1 - 2e-18 66.8 0.0 2.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 OAJ32519.1 - 2.6e-06 27.2 0.5 2.6e-06 27.2 0.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 OAJ32519.1 - 0.0013 18.5 0.6 0.0013 18.5 0.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 OAJ32519.1 - 0.027 14.8 0.3 0.027 14.8 0.3 1.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 OAJ32519.1 - 0.044 13.8 1.3 0.11 12.6 1.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 OAJ32519.1 - 0.19 11.6 0.7 0.46 10.4 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 OAJ32519.1 - 5.9 6.8 5.5 4.8 7.1 1.3 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Gaa1 PF04114.14 OAJ32521.1 - 2.9e-71 241.0 4.0 2.6e-52 178.5 0.0 3.4 3 0 0 3 3 3 3 Gaa1-like, GPI transamidase component WD40 PF00400.32 OAJ32522.1 - 2e-31 107.5 14.7 4.5e-06 27.3 0.5 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 OAJ32522.1 - 5.7e-11 42.1 0.2 1.6e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 OAJ32522.1 - 3.6e-05 23.2 0.3 8.8e-05 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 OAJ32522.1 - 0.00018 21.3 0.1 0.00041 20.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 OAJ32522.1 - 0.13 12.7 0.2 52 4.5 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain adh_short_C2 PF13561.6 OAJ32523.1 - 2.6e-59 200.6 2.1 3.3e-59 200.3 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 OAJ32523.1 - 6.9e-44 149.6 1.0 9.1e-44 149.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 OAJ32523.1 - 2.3e-10 40.7 0.2 3.7e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 OAJ32523.1 - 0.033 14.7 0.3 0.066 13.8 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 OAJ32523.1 - 0.035 13.5 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 OAJ32523.1 - 0.077 12.4 0.1 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Arf PF00025.21 OAJ32526.1 - 1.4e-79 265.6 0.1 1.6e-79 265.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 OAJ32526.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 OAJ32526.1 - 4.5e-14 52.3 0.0 5.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 OAJ32526.1 - 2e-13 50.2 0.8 1.7e-09 37.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 OAJ32526.1 - 3.7e-13 49.4 0.0 4.1e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 OAJ32526.1 - 1.2e-10 41.2 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 OAJ32526.1 - 3.3e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 OAJ32526.1 - 0.0067 15.8 0.5 0.017 14.4 0.5 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_CH_N PF12471.8 OAJ32527.1 - 6.3e-88 293.6 0.0 1e-87 292.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 OAJ32527.1 - 1.2e-15 57.5 0.0 1.8e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Sugar_tr PF00083.24 OAJ32528.1 - 7.1e-27 94.4 5.4 9e-22 77.5 0.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ32528.1 - 5.9e-25 87.9 30.4 4.6e-17 62.0 13.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.22 OAJ32529.1 - 1.6e-98 330.9 0.0 2.1e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pyr_redox_2 PF07992.14 OAJ32530.1 - 9.3e-24 84.2 0.1 7.3e-14 51.7 0.0 4.2 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 OAJ32530.1 - 5.2e-13 49.4 1.3 2.6e-08 34.3 1.1 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Myosin_N PF02736.19 OAJ32530.1 - 0.064 13.1 0.0 14 5.6 0.1 2.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Thi4 PF01946.17 OAJ32530.1 - 0.078 12.2 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 OAJ32530.1 - 0.12 11.7 0.0 1.5 8.0 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MARVEL PF01284.23 OAJ32531.1 - 4.2 7.4 14.1 9.2 6.3 14.1 1.6 1 0 0 1 1 1 0 Membrane-associating domain Corona_nucleoca PF00937.18 OAJ32531.1 - 7.4 5.5 12.5 2.8 6.9 10.0 1.5 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein YidD PF01809.18 OAJ32532.1 - 0.052 13.4 0.7 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Putative membrane protein insertion efficiency factor Nbl1_Borealin_N PF10444.9 OAJ32535.1 - 3.2e-08 33.1 0.8 5.7e-08 32.3 0.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Edc3_linker PF16598.5 OAJ32535.1 - 0.062 14.0 0.8 0.062 14.0 0.8 2.5 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 FAM176 PF14851.6 OAJ32536.1 - 1.2 8.8 3.0 19 4.9 0.3 2.5 3 0 0 3 3 3 0 FAM176 family Hydrolase_like PF13242.6 OAJ32537.1 - 9.1e-22 76.9 0.0 1.7e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 OAJ32537.1 - 1.1e-17 63.9 0.0 2.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TENA_THI-4 PF03070.16 OAJ32538.1 - 2.2e-11 44.0 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family FoP_duplication PF13865.6 OAJ32538.1 - 3e-05 24.5 0.9 7.6e-05 23.2 0.9 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Gar1 PF04410.14 OAJ32539.1 - 9.8e-28 96.9 0.5 2.1e-15 56.8 0.1 3.3 3 0 0 3 3 3 2 Gar1/Naf1 RNA binding region AF-4 PF05110.13 OAJ32539.1 - 0.00027 19.2 18.7 0.00027 19.2 18.7 4.2 3 1 1 4 4 4 2 AF-4 proto-oncoprotein RIBIOP_C PF04950.12 OAJ32541.1 - 8.9e-102 340.4 0.0 1.3e-101 339.9 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 OAJ32541.1 - 3.5e-22 78.3 0.0 1e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF4611 PF15387.6 OAJ32542.1 - 0.03 14.5 2.9 0.056 13.7 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SRF-TF PF00319.18 OAJ32543.1 - 4.6e-16 58.0 0.1 7.3e-16 57.4 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Serglycin PF04360.12 OAJ32543.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 3.0 3 0 0 3 3 3 2 Serglycin Pap_E4 PF02711.14 OAJ32545.1 - 0.096 13.7 2.7 0.12 13.4 2.7 1.3 1 0 0 1 1 1 0 E4 protein WLM PF08325.10 OAJ32545.1 - 0.18 11.9 1.5 0.29 11.2 1.5 1.3 1 0 0 1 1 1 0 WLM domain SARAF PF06682.12 OAJ32545.1 - 0.27 10.8 5.7 0.3 10.7 5.7 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CCDC53 PF10152.9 OAJ32545.1 - 0.45 10.9 3.0 0.52 10.7 3.0 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 OAJ32545.1 - 0.81 10.1 6.9 0.91 9.9 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4719 PF15843.5 OAJ32545.1 - 2.6 8.1 6.3 3.1 7.9 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) EMP24_GP25L PF01105.24 OAJ32546.1 - 2.8e-50 170.8 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 OAJ32546.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain Ras PF00071.22 OAJ32547.1 - 1.7e-50 170.8 0.1 2e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 OAJ32547.1 - 1.3e-30 106.1 0.0 2.1e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 OAJ32547.1 - 1.6e-11 44.0 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 OAJ32547.1 - 0.00031 20.2 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 OAJ32547.1 - 0.00038 19.7 0.1 0.083 12.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 OAJ32547.1 - 0.0055 16.8 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 OAJ32547.1 - 0.021 15.2 0.3 0.74 10.2 0.3 2.2 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 OAJ32547.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 OAJ32547.1 - 0.066 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 OAJ32547.1 - 0.089 12.3 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 OAJ32547.1 - 0.11 12.5 0.2 13 5.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 OAJ32547.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 OAJ32547.1 - 0.12 11.6 0.2 0.19 11.0 0.1 1.5 2 0 0 2 2 2 0 Septin TsaE PF02367.17 OAJ32547.1 - 0.13 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thioredoxin PF00085.20 OAJ32548.1 - 1.7e-21 76.2 0.0 2.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 OAJ32548.1 - 2e-06 28.2 0.0 6.5e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 OAJ32548.1 - 8.4e-05 22.5 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 OAJ32548.1 - 0.00025 21.3 0.0 0.013 15.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like KaiB PF07689.12 OAJ32548.1 - 0.00066 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 KaiB domain Thioredoxin_3 PF13192.6 OAJ32548.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 OAJ32548.1 - 0.0028 17.8 0.1 0.0056 16.8 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 OAJ32548.1 - 0.0059 16.5 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 OAJ32548.1 - 0.0061 16.3 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF836 PF05768.14 OAJ32548.1 - 0.0064 16.9 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 OAJ32548.1 - 0.0088 15.7 0.1 0.036 13.7 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 OAJ32548.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 OAJ32548.1 - 0.013 15.4 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 OAJ32548.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 OAJ32548.1 - 0.03 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin RasGAP PF00616.19 OAJ32550.1 - 2.4e-20 73.1 0.0 1.6e-12 47.5 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 OAJ32550.1 - 1.7e-09 38.0 0.0 5.8e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 OAJ32550.1 - 0.00011 22.2 0.1 0.0009 19.2 0.0 2.6 2 0 0 2 2 2 1 Cell morphogenesis C-terminal bZIP_1 PF00170.21 OAJ32551.1 - 0.00013 22.0 9.9 0.00013 22.0 9.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 OAJ32551.1 - 0.0035 17.4 9.0 0.0035 17.4 9.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Serglycin PF04360.12 OAJ32552.1 - 0.56 10.1 10.5 0.074 13.0 2.5 2.8 2 0 0 2 2 2 0 Serglycin Oxysterol_BP PF01237.18 OAJ32553.1 - 2.7e-85 286.4 1.6 3.8e-83 279.4 1.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Aminotran_1_2 PF00155.21 OAJ32554.1 - 1.4e-33 116.6 0.0 1.7e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PAC2 PF09754.9 OAJ32555.1 - 3.9e-25 89.1 0.0 5e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 PAC2 family OrsD PF12013.8 OAJ32556.1 - 8e-06 26.3 1.3 0.00085 19.8 0.1 2.4 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D bZIP_1 PF00170.21 OAJ32557.1 - 0.00013 22.0 10.3 0.00028 20.9 9.6 1.9 1 1 1 2 2 2 1 bZIP transcription factor DUF4148 PF13663.6 OAJ32557.1 - 0.042 14.0 4.6 0.072 13.3 1.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) FHIPEP PF00771.20 OAJ32557.1 - 0.23 9.9 1.6 0.38 9.2 1.6 1.3 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.15 OAJ32557.1 - 0.34 11.0 0.3 0.57 10.3 0.3 1.2 1 0 0 1 1 1 0 CD20-like family SelP_N PF04592.14 OAJ32557.1 - 2.2 7.6 16.7 4.1 6.7 16.7 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM76 PF16046.5 OAJ32557.1 - 7.9 5.7 10.6 2.2 7.5 4.1 2.1 2 0 0 2 2 2 0 FAM76 protein Macoilin PF09726.9 OAJ32557.1 - 8.3 4.8 14.8 2.3 6.7 2.0 2.1 2 0 0 2 2 2 0 Macoilin family MFS_1 PF07690.16 OAJ32558.1 - 4.5e-27 94.9 29.9 8.7e-27 94.0 29.9 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily MutS_V PF00488.21 OAJ32559.1 - 3.4e-62 209.8 0.0 9.6e-62 208.4 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 OAJ32559.1 - 3.8e-32 112.1 8.6 1.7e-31 110.0 8.6 2.1 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 OAJ32559.1 - 6.5e-19 68.2 0.0 1.5e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 OAJ32559.1 - 1.8e-08 34.7 1.2 6.2e-08 33.0 0.0 2.6 3 0 0 3 3 3 1 MutS domain II AAA_27 PF13514.6 OAJ32559.1 - 0.00071 19.2 0.0 0.0025 17.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 OAJ32559.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain HHV-1_VABD PF16852.5 OAJ32559.1 - 0.18 11.8 1.5 1.7 8.7 0.2 2.9 2 0 0 2 2 2 0 Herpes viral adaptor-to-host cellular mRNA binding domain AAA_23 PF13476.6 OAJ32559.1 - 1.5 9.3 0.0 1.5 9.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF2052 PF09747.9 OAJ32559.1 - 4.9 7.2 5.5 0.98 9.5 1.6 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pyr_redox_2 PF07992.14 OAJ32560.1 - 1.4e-43 149.3 0.7 2.4e-41 141.9 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 OAJ32560.1 - 1.7e-18 66.6 0.0 3.3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 OAJ32560.1 - 9.4e-17 61.4 6.4 2e-13 50.7 0.7 3.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ32560.1 - 1.1e-15 57.4 0.0 3.1e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 OAJ32560.1 - 4.4e-15 55.8 5.5 1.7e-10 41.1 6.1 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 OAJ32560.1 - 7.1e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 OAJ32560.1 - 2.8e-11 43.2 0.1 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Rubredoxin_C PF18267.1 OAJ32560.1 - 1.7e-05 24.7 0.2 0.045 13.7 0.0 2.9 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 OAJ32560.1 - 2e-05 24.0 0.1 11 5.2 0.0 4.1 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 OAJ32560.1 - 0.00042 20.0 0.9 0.34 10.4 0.1 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 OAJ32560.1 - 0.00047 19.3 4.5 0.097 11.7 0.2 3.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 OAJ32560.1 - 0.0022 18.0 4.2 2.7 8.0 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.18 OAJ32560.1 - 0.013 15.8 2.0 1.6 9.0 0.3 2.8 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 OAJ32560.1 - 0.015 14.5 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 OAJ32560.1 - 0.021 15.3 1.3 4.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 OAJ32560.1 - 0.17 12.2 0.2 1.3 9.3 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 OAJ32560.1 - 0.2 11.9 0.7 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Oxidored_molyb PF00174.19 OAJ32561.1 - 1.1e-51 174.9 0.0 1.9e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 OAJ32561.1 - 6.1e-43 146.1 0.1 1.3e-42 145.1 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 OAJ32561.1 - 6.1e-25 87.5 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 OAJ32561.1 - 4.1e-22 78.9 0.0 3.3e-21 76.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 OAJ32561.1 - 1.4e-18 66.8 0.0 2.9e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 OAJ32561.1 - 0.00044 20.4 0.0 0.0078 16.3 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Voltage_CLC PF00654.20 OAJ32562.1 - 7.6e-91 305.0 29.9 1.5e-90 304.1 29.9 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 OAJ32562.1 - 8.7e-12 45.3 0.0 5.6e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain Nic96 PF04097.14 OAJ32563.1 - 2.9e-169 564.4 0.0 4.1e-169 564.0 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 NESP55 PF06390.12 OAJ32564.1 - 0.55 9.8 1.7 0.69 9.5 1.7 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Palm_thioest PF02089.15 OAJ32565.1 - 3.4e-05 23.8 0.0 5.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 OAJ32565.1 - 0.0015 18.2 0.0 0.029 14.0 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 OAJ32565.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 OAJ32565.1 - 0.004 16.9 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 OAJ32565.1 - 0.0081 15.4 0.0 0.029 13.5 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase RRS1 PF04939.12 OAJ32566.1 - 9.5e-53 178.4 0.8 1.3e-52 177.9 0.8 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Peptidase_S24 PF00717.23 OAJ32567.1 - 2.1e-09 37.2 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Phage_AlpA PF05930.12 OAJ32569.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Aminotran_1_2 PF00155.21 OAJ32570.1 - 2e-90 303.6 0.0 2.3e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Complex1_51K PF01512.17 OAJ32571.1 - 2.7e-48 163.7 0.0 4.5e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 OAJ32571.1 - 1.4e-31 108.4 0.2 2.8e-31 107.4 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 OAJ32571.1 - 3.7e-08 33.1 0.0 8.7e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 OAJ32571.1 - 5.2 7.2 6.1 0.38 10.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Peptidase_C14 PF00656.22 OAJ32572.1 - 6.3e-60 203.2 0.0 7.8e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Aminotran_1_2 PF00155.21 OAJ32573.1 - 3.4e-70 237.0 0.0 4.5e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 OAJ32573.1 - 8.4e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 OAJ32573.1 - 0.00029 19.5 0.0 0.0011 17.6 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 OAJ32573.1 - 0.013 14.8 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Arf PF00025.21 OAJ32575.1 - 1.5e-64 216.6 0.0 1.7e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 OAJ32575.1 - 4.7e-09 35.9 0.0 1.7e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 OAJ32575.1 - 8.2e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 OAJ32575.1 - 6.2e-08 32.4 0.0 7.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 OAJ32575.1 - 7.9e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 OAJ32575.1 - 8.5e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 OAJ32575.1 - 2.8e-05 23.6 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 OAJ32575.1 - 0.04 13.5 0.1 0.86 9.1 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain CENP-M PF11111.8 OAJ32575.1 - 0.042 13.0 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) cobW PF02492.19 OAJ32575.1 - 0.045 13.3 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 OAJ32575.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L26 PF16906.5 OAJ32576.1 - 5.9e-39 132.4 2.2 7.2e-39 132.1 2.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 OAJ32576.1 - 1.5e-08 34.3 1.9 3.2e-08 33.3 1.9 1.6 1 0 0 1 1 1 1 KOW motif SIR2 PF02146.17 OAJ32577.1 - 3.9e-52 176.7 0.0 2.4e-51 174.2 0.0 2.2 2 1 0 2 2 2 1 Sir2 family DUF592 PF04574.13 OAJ32577.1 - 2.2e-08 34.0 0.3 2.8e-07 30.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 OAJ32577.1 - 0.18 11.5 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain WD40 PF00400.32 OAJ32578.1 - 2.3e-12 47.2 9.0 7.5e-06 26.6 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 OAJ32578.1 - 2.6e-05 24.4 0.0 0.00038 20.7 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Zip PF02535.22 OAJ32579.1 - 2.9 7.0 13.7 1.3 8.1 3.1 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter Nuf2 PF03800.14 OAJ32580.1 - 3.4e-33 114.7 0.0 1e-32 113.2 0.0 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 OAJ32580.1 - 6.7e-20 71.3 20.8 6.7e-20 71.3 20.8 4.0 1 1 3 4 4 4 2 Designed helical repeat protein 10 domain EcKinase PF02958.20 OAJ32580.1 - 0.015 14.6 2.3 0.015 14.6 2.3 1.9 2 1 0 2 2 2 0 Ecdysteroid kinase DUF4083 PF13314.6 OAJ32580.1 - 0.2 11.6 0.9 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) VPS11_C PF12451.8 OAJ32580.1 - 0.86 9.9 6.7 6.1 7.1 0.6 3.6 3 0 0 3 3 2 0 Vacuolar protein sorting protein 11 C terminal DUF3584 PF12128.8 OAJ32580.1 - 1.3 6.4 38.2 1.7 6.0 38.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 OAJ32580.1 - 1.4 9.3 7.5 0.71 10.2 0.3 3.3 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 OAJ32580.1 - 2 7.2 40.6 9.1 5.1 25.0 3.1 1 1 3 4 4 4 0 Spc7 kinetochore protein UPF0242 PF06785.11 OAJ32580.1 - 3.2 7.8 37.8 0.36 10.9 3.0 3.3 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 OAJ32580.1 - 4.3 6.3 33.0 1.3 8.0 16.9 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 OAJ32580.1 - 5.8 6.2 42.2 1.3 8.3 15.0 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3037 PF11236.8 OAJ32580.1 - 8 6.9 11.7 0.73 10.3 2.8 3.0 1 1 2 4 4 4 0 Protein of unknown function (DUF3037) Spectrin PF00435.21 OAJ32580.1 - 9.5 6.8 25.7 0.66 10.5 7.0 3.9 2 1 1 4 4 4 0 Spectrin repeat RNA_lig_T4_1 PF09511.10 OAJ32581.1 - 1e-83 280.6 0.0 1.6e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.11 OAJ32581.1 - 9.6e-25 87.5 0.0 5.9e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 OAJ32581.1 - 1.6e-23 83.6 0.2 2.1e-14 53.9 0.0 2.4 1 1 1 2 2 2 2 tRNA ligase kinase domain KTI12 PF08433.10 OAJ32581.1 - 0.052 13.0 0.3 2.2 7.6 0.3 2.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF3381 PF11861.8 OAJ32581.1 - 4.1 7.2 9.7 9.3 6.0 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) WD40 PF00400.32 OAJ32582.1 - 4.1e-44 147.7 22.8 3.2e-06 27.8 0.1 9.7 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 OAJ32582.1 - 3.2e-11 42.9 0.1 6.2e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 OAJ32582.1 - 8.8e-10 38.2 0.1 1.8e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 OAJ32582.1 - 8.4e-08 31.3 9.9 0.075 11.7 0.2 6.7 4 2 2 7 7 7 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 OAJ32582.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box ANAPC4_WD40 PF12894.7 OAJ32582.1 - 0.0034 17.6 0.2 23 5.4 0.0 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 OAJ32582.1 - 0.36 9.7 5.8 6.7 5.5 0.3 4.0 4 1 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain DUF4698 PF15769.5 OAJ32582.1 - 9.7 5.1 6.9 23 3.9 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Pkinase PF00069.25 OAJ32584.1 - 2.1e-27 96.2 0.0 2.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32584.1 - 4.7e-16 58.8 0.0 6.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 OAJ32584.1 - 1.7e-09 37.0 0.1 1.7e-09 37.0 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 OAJ32584.1 - 8.2e-05 22.6 0.6 0.0081 16.1 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 OAJ32584.1 - 0.04 12.9 0.1 0.059 12.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 OAJ32584.1 - 0.046 13.1 0.3 0.14 11.5 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMM1 PF10296.9 OAJ32585.1 - 0.00013 21.1 0.0 0.00051 19.2 0.0 1.9 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Pescadillo_N PF06732.11 OAJ32586.1 - 9.8e-120 399.2 0.0 2.1e-119 398.1 0.0 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 OAJ32586.1 - 2.4e-07 31.1 0.1 1e-06 29.0 0.0 2.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 OAJ32586.1 - 8e-05 22.9 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 OAJ32586.1 - 0.0085 16.4 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Mucin PF01456.17 OAJ32587.1 - 0.0022 18.0 17.2 0.026 14.5 8.5 2.5 2 1 0 2 2 2 2 Mucin-like glycoprotein Pkinase PF00069.25 OAJ32588.1 - 1.7e-64 217.7 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32588.1 - 7.8e-29 100.7 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 OAJ32588.1 - 3.7e-15 56.3 0.7 3.7e-15 56.3 0.7 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 OAJ32588.1 - 3.9e-08 33.0 0.0 8.3e-07 28.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 OAJ32588.1 - 3.1e-07 30.6 0.1 0.00081 19.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain Haspin_kinase PF12330.8 OAJ32588.1 - 0.0082 15.1 0.1 0.0082 15.1 0.1 1.7 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 OAJ32588.1 - 0.014 15.0 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 OAJ32588.1 - 0.05 13.5 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fibrinogen_BP PF08017.11 OAJ32589.1 - 0.042 12.3 1.9 0.086 11.3 1.9 1.4 1 0 0 1 1 1 0 Fibrinogen binding protein zf-C2H2_4 PF13894.6 OAJ32589.1 - 0.77 10.8 5.2 0.2 12.6 1.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger BAF1_ABF1 PF04684.13 OAJ32589.1 - 2 7.4 7.8 1.2 8.1 1.6 2.7 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor Ish1 PF10281.9 OAJ32590.1 - 1.4e-60 201.3 26.0 3.2e-13 49.7 0.3 6.5 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 OAJ32590.1 - 0.00048 19.8 0.0 1.3 8.8 0.0 4.2 4 0 0 4 4 4 1 SAP domain GYF PF02213.16 OAJ32590.1 - 0.00051 19.7 2.0 0.034 13.8 0.1 2.6 2 0 0 2 2 2 2 GYF domain LEM PF03020.15 OAJ32590.1 - 0.0063 16.0 0.0 3.4 7.3 0.0 3.6 4 0 0 4 4 4 1 LEM domain HeH PF12949.7 OAJ32590.1 - 0.52 10.1 5.4 2.4 8.0 0.0 4.2 6 0 0 6 6 6 0 HeH/LEM domain RRM_1 PF00076.22 OAJ32591.1 - 1.4e-18 66.5 0.1 2.6e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ32591.1 - 2.5e-08 33.6 0.0 5.8e-06 25.9 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 OAJ32591.1 - 0.0065 16.3 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF1027 PF06265.11 OAJ32591.1 - 0.044 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Limkain-b1 PF11608.8 OAJ32591.1 - 0.056 13.5 0.2 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 DUF4523 PF15023.6 OAJ32591.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Ferritin_2 PF13668.6 OAJ32592.1 - 6e-43 146.3 4.7 9e-43 145.7 4.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain RNA_pol_Rpb2_6 PF00562.28 OAJ32593.1 - 2.8e-121 405.3 0.3 1.5e-117 393.0 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 OAJ32593.1 - 2e-62 210.3 0.1 3e-62 209.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 OAJ32593.1 - 2.5e-47 161.0 0.0 4.9e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 OAJ32593.1 - 1.5e-31 108.6 0.1 3.9e-31 107.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 OAJ32593.1 - 1e-25 89.6 0.1 3e-25 88.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 OAJ32593.1 - 2.2e-23 82.3 0.4 6.1e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 OAJ32593.1 - 1.3e-19 70.5 0.1 3.5e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CWC25 PF12542.8 OAJ32594.1 - 2e-25 89.7 1.0 2e-25 89.7 1.0 3.7 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 OAJ32594.1 - 6.3e-14 51.9 12.2 6.3e-14 51.9 12.2 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Haspin_kinase PF12330.8 OAJ32595.1 - 5.8e-49 167.0 0.0 1.4e-48 165.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain DUF5343 PF17278.2 OAJ32595.1 - 0.029 14.4 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) CAF1A PF12253.8 OAJ32595.1 - 0.12 12.6 7.2 0.54 10.5 7.2 2.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Ribosomal_L1 PF00687.21 OAJ32596.1 - 6e-24 84.9 0.0 6e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family PhdYeFM_antitox PF02604.19 OAJ32596.1 - 0.056 13.3 0.2 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system NARP1 PF12569.8 OAJ32597.1 - 1.1e-152 509.5 7.1 1.1e-151 506.2 7.1 2.1 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 OAJ32597.1 - 8.1e-12 44.3 26.6 1.9e-05 24.4 0.0 10.1 11 1 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ32597.1 - 1.4e-11 43.6 6.1 0.0019 18.1 0.0 6.6 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ32597.1 - 1.7e-11 43.4 3.2 4.2e-05 23.2 0.1 6.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ32597.1 - 1.9e-10 40.7 31.3 0.022 15.6 0.1 10.6 11 1 1 12 12 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 OAJ32597.1 - 7.7e-08 32.4 11.1 0.00033 20.7 0.3 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ32597.1 - 4.9e-07 30.2 40.8 0.072 13.6 0.0 9.4 8 2 1 9 9 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ32597.1 - 1.2e-06 28.7 15.9 0.031 14.6 0.1 6.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ32597.1 - 6.9e-06 26.1 0.2 3.5 8.2 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32597.1 - 0.0079 16.3 16.2 0.39 11.0 0.1 7.2 10 0 0 10 10 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ32597.1 - 0.011 16.3 14.6 0.059 14.0 0.1 6.9 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ32597.1 - 0.03 15.0 0.0 0.07 13.8 0.0 10.7 10 1 1 11 11 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ32597.1 - 0.031 13.9 5.1 2.1 8.1 0.0 4.5 5 0 0 5 5 5 0 TPR repeat Fis1_TPR_C PF14853.6 OAJ32597.1 - 0.033 14.3 0.3 31 4.7 0.0 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF789 PF05623.12 OAJ32597.1 - 0.05 13.3 0.3 0.1 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) TPR_10 PF13374.6 OAJ32597.1 - 0.052 13.4 6.5 11 6.0 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TAF4 PF05236.14 OAJ32597.1 - 0.36 10.5 11.3 0.86 9.3 11.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family RNA_pol_Rpc4 PF05132.14 OAJ32597.1 - 8.7 6.8 7.8 31 5.0 7.8 1.9 1 0 0 1 1 1 0 RNA polymerase III RPC4 AMP-binding PF00501.28 OAJ32598.1 - 1.2e-90 304.1 0.0 1.4e-89 300.7 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 OAJ32598.1 - 1.6e-10 41.8 0.3 4.2e-10 40.5 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Amino_oxidase PF01593.24 OAJ32599.1 - 1.6e-57 195.8 0.0 1.9e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 OAJ32599.1 - 8.9e-10 38.7 0.2 1.9e-09 37.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 OAJ32599.1 - 1e-06 28.6 0.1 2.2e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 OAJ32599.1 - 2.6e-06 26.4 0.5 0.0031 16.3 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 OAJ32599.1 - 8.6e-05 23.0 0.4 0.0084 16.7 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 OAJ32599.1 - 0.00022 20.5 0.2 0.00032 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 OAJ32599.1 - 0.00022 20.6 0.8 0.022 14.0 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 OAJ32599.1 - 0.00063 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 OAJ32599.1 - 0.00086 18.6 1.4 0.0056 15.9 0.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 OAJ32599.1 - 0.0011 18.9 0.1 1.8 8.5 0.2 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.17 OAJ32599.1 - 0.0031 16.8 0.4 0.0059 15.9 0.4 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 OAJ32599.1 - 0.0036 16.7 0.4 0.0057 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 OAJ32599.1 - 0.021 13.9 0.1 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein MCRA PF06100.11 OAJ32599.1 - 0.096 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 MCRA family GATase_3 PF07685.14 OAJ32599.1 - 0.12 12.0 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain GIDA PF01134.22 OAJ32599.1 - 0.14 11.2 0.8 2.5 7.1 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF349 PF03993.12 OAJ32600.1 - 5.1 7.5 10.8 0.13 12.6 2.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) EspF PF04806.12 OAJ32602.1 - 0.12 12.8 6.7 0.33 11.4 4.6 2.8 2 0 0 2 2 2 0 EspF protein repeat Podoplanin PF05808.11 OAJ32603.1 - 0.0037 17.4 19.8 0.014 15.5 17.8 2.4 2 1 0 2 2 2 1 Podoplanin Adeno_E3_CR2 PF02439.15 OAJ32603.1 - 0.37 10.6 3.5 0.66 9.8 3.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIA PF03153.13 OAJ32603.1 - 1.5 8.8 28.7 0.11 12.5 14.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_5 PF12695.7 OAJ32604.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 OAJ32604.1 - 0.067 12.5 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 OAJ32604.1 - 0.071 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pirin PF02678.16 OAJ32605.1 - 1.1e-27 96.1 0.0 2.1e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 OAJ32605.1 - 5.2e-24 84.6 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 OAJ32605.1 - 0.0099 15.6 0.6 0.047 13.4 0.7 2.0 2 0 0 2 2 2 1 Cupin domain Pro_isomerase PF00160.21 OAJ32606.1 - 2.4e-28 99.4 0.0 3.9e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 OAJ32606.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipase_3 PF01764.25 OAJ32607.1 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 OAJ32607.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CTP_transf_like PF01467.26 OAJ32608.1 - 1.8e-26 93.1 0.0 2.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like MIP PF00230.20 OAJ32609.1 - 1.9e-40 139.0 14.5 2.6e-40 138.6 14.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Nitrate_red_gam PF02665.14 OAJ32609.1 - 0.45 10.0 2.9 0.62 9.6 2.9 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Bud13 PF09736.9 OAJ32609.1 - 1.5 9.2 8.9 2.4 8.6 8.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NPAT_C PF15712.5 OAJ32609.1 - 4.3 5.9 5.9 7 5.2 5.9 1.2 1 0 0 1 1 1 0 NPAT C terminus SRAP PF02586.14 OAJ32610.1 - 1e-58 198.5 0.0 1.2e-57 195.0 0.0 2.3 2 1 0 2 2 2 1 SOS response associated peptidase (SRAP) PAXIP1_C PF15364.6 OAJ32610.1 - 3.7 7.9 10.8 3.3 8.0 7.9 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2052 PF09747.9 OAJ32610.1 - 6.1 6.9 10.5 9.6 6.3 8.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Amastin PF07344.11 OAJ32611.1 - 1.2 9.0 9.7 0.26 11.1 5.6 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein PMP22_Claudin PF00822.20 OAJ32611.1 - 5.8 6.8 9.6 0.32 10.8 3.4 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Methyltr_RsmB-F PF01189.17 OAJ32612.1 - 1e-17 64.5 0.2 5.1e-09 36.1 0.1 3.4 2 1 1 3 3 3 3 16S rRNA methyltransferase RsmB/F HWE_HK PF07536.14 OAJ32612.1 - 0.051 14.3 0.3 0.051 14.3 0.3 2.5 3 0 0 3 3 3 0 HWE histidine kinase DUF4710 PF15828.5 OAJ32612.1 - 0.055 13.6 8.8 0.99 9.6 5.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) TSGP1 PF07771.11 OAJ32612.1 - 1.6 8.9 4.7 4.5 7.4 4.7 1.7 1 0 0 1 1 1 0 Tick salivary peptide group 1 Sas10_Utp3 PF04000.15 OAJ32613.1 - 9e-14 51.9 0.3 2.6e-13 50.4 0.3 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family WD40_4 PF16300.5 OAJ32614.1 - 1.5e-21 76.0 1.5 1.2e-14 54.0 0.0 2.7 2 0 0 2 2 2 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 OAJ32614.1 - 0.088 13.1 0.1 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 OAJ32614.1 - 0.33 11.9 5.4 10 7.2 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat MFS_1 PF07690.16 OAJ32615.1 - 6.2e-28 97.7 43.9 1.7e-26 93.0 38.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Plus-3 PF03126.18 OAJ32616.1 - 1.5e-14 54.5 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain DLH PF01738.18 OAJ32617.1 - 5.3e-14 52.3 0.6 6.2e-14 52.1 0.6 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family baeRF_family7 PF18849.1 OAJ32617.1 - 0.088 13.0 0.1 0.25 11.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 Nup35_RRM PF05172.13 OAJ32618.1 - 3.3e-06 27.0 0.0 7.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 OAJ32618.1 - 0.00034 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 OAJ32619.1 - 5.2e-08 32.6 0.9 0.012 15.4 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 OAJ32621.1 - 4.4e-232 773.0 0.0 5.6e-232 772.6 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Se-cys_synth_N PF12390.8 OAJ32621.1 - 0.00029 21.0 1.7 0.00082 19.5 0.3 2.7 2 0 0 2 2 2 1 Selenocysteine synthase N terminal ANAPC4_WD40 PF12894.7 OAJ32621.1 - 0.043 14.1 0.0 6.9 7.0 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CCDC106 PF15794.5 OAJ32621.1 - 0.12 12.1 4.1 0.22 11.2 4.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Peptidase_M24 PF00557.24 OAJ32622.1 - 1.8e-46 158.5 0.0 2.3e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3663 PF12404.8 OAJ32622.1 - 0.051 13.6 0.3 8.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Peptidase PCI PF01399.27 OAJ32623.1 - 1.7e-10 41.3 0.2 6e-10 39.6 0.2 2.0 1 0 0 1 1 1 1 PCI domain Peptidase_M15_2 PF05951.13 OAJ32623.1 - 0.39 10.4 7.5 0.83 9.3 0.0 3.6 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF882) DUF829 PF05705.14 OAJ32624.1 - 1.4e-24 87.3 0.0 1.6e-15 57.7 0.0 3.5 3 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) DUF4266 PF14086.6 OAJ32624.1 - 0.16 12.9 0.3 0.4 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Avl9 PF09794.9 OAJ32625.1 - 1.5e-121 405.7 0.0 1.9e-121 405.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 OAJ32625.1 - 1.3e-07 31.5 0.0 0.01 15.4 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 OAJ32625.1 - 4e-06 26.8 0.0 0.00095 19.1 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 OAJ32625.1 - 0.00061 20.3 0.1 0.0018 18.8 0.1 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Hepar_II_III PF07940.13 OAJ32626.1 - 2.3e-06 27.4 0.4 4.4e-06 26.5 0.4 1.5 1 0 0 1 1 1 1 Heparinase II/III-like protein Ribosomal_S2 PF00318.20 OAJ32627.1 - 1.8e-30 105.8 0.1 4e-16 58.9 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 OAJ32627.1 - 4.5e-11 44.0 1.9 8.3e-11 43.1 1.9 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Pkinase PF00069.25 OAJ32628.1 - 1.2e-23 83.9 0.0 2.8e-19 69.5 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 OAJ32628.1 - 2.7e-12 46.5 0.0 4.2e-09 36.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase ECH_1 PF00378.20 OAJ32629.1 - 4.3e-81 271.9 1.4 5.2e-81 271.6 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 OAJ32629.1 - 8.6e-36 124.1 2.6 1.9e-34 119.6 2.7 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 OAJ32629.1 - 0.00067 19.6 1.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 SDH_sah PF01972.16 OAJ32629.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Porphobil_deam PF01379.20 OAJ32630.1 - 3.3e-67 226.0 0.0 1.2e-66 224.2 0.0 1.9 2 1 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 OAJ32630.1 - 1.2e-12 48.0 0.0 2.6e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 Porphobilinogen deaminase, C-terminal domain MIP PF00230.20 OAJ32632.1 - 2.4e-48 164.8 5.9 3.4e-48 164.3 5.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF3925 PF13063.6 OAJ32632.1 - 0.073 13.3 2.1 0.23 11.7 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3925) GTP_EFTU PF00009.27 OAJ32633.1 - 9.6e-44 149.2 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 OAJ32633.1 - 1.1e-12 48.3 0.0 2.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 OAJ32633.1 - 1.9e-08 34.4 0.0 9.3e-07 28.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 OAJ32633.1 - 9.2e-06 26.0 0.1 2.7e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 OAJ32633.1 - 0.00089 18.7 0.0 0.77 9.2 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 OAJ32633.1 - 0.0058 16.5 0.7 0.034 14.0 0.3 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 4 cobW PF02492.19 OAJ32633.1 - 0.032 13.8 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 OAJ32633.1 - 0.047 13.0 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 OAJ32633.1 - 0.091 12.3 0.0 6.5 6.3 0.0 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 OAJ32633.1 - 0.11 12.5 0.0 1 9.4 0.0 2.1 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 OAJ32633.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 OAJ32633.1 - 0.19 10.8 0.1 0.57 9.3 0.1 1.6 2 0 0 2 2 2 0 G-protein alpha subunit HBS1_N PF08938.10 OAJ32634.1 - 8.8e-11 42.0 0.7 2e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 HBS1 N-terminus Cdh1_DBD_1 PF18196.1 OAJ32634.1 - 0.062 13.6 2.1 0.21 11.9 0.1 2.7 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 Rhodanese PF00581.20 OAJ32635.1 - 1.5e-15 57.6 0.0 4.4e-08 33.6 0.0 3.4 2 2 1 3 3 3 3 Rhodanese-like domain ThiC-associated PF13667.6 OAJ32635.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 ThiC-associated domain DUF3613 PF12266.8 OAJ32635.1 - 1.4 8.8 6.2 8.6 6.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) RNA_pol_Rbc25 PF08292.12 OAJ32636.1 - 1.4e-29 103.0 0.0 3.1e-24 85.7 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 OAJ32636.1 - 5.9e-16 58.6 0.1 1.1e-15 57.7 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 OAJ32636.1 - 0.076 13.4 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 S1 RNA binding domain Fip1 PF05182.13 OAJ32638.1 - 2.8e-18 65.1 0.6 5.1e-18 64.3 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Lipase_GDSL PF00657.22 OAJ32639.1 - 4.3e-07 30.1 0.0 5.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 OAJ32639.1 - 4.5e-05 23.9 0.6 0.00027 21.4 0.6 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3385 PF11865.8 OAJ32640.1 - 1.2e-51 174.8 0.1 1.7e-46 158.0 0.0 4.8 3 2 2 5 5 5 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 OAJ32640.1 - 3.4e-20 72.2 14.1 0.00021 21.6 0.0 10.6 8 2 2 10 10 10 3 HEAT repeats HEAT PF02985.22 OAJ32640.1 - 1.9e-13 49.4 18.2 2 8.9 0.1 12.2 12 0 0 12 12 12 5 HEAT repeat UME PF08064.13 OAJ32640.1 - 1.5e-06 28.1 0.0 0.15 12.0 0.0 5.6 3 3 2 5 5 5 2 UME (NUC010) domain HEAT_EZ PF13513.6 OAJ32640.1 - 1.5e-06 28.5 32.1 0.033 14.7 0.1 12.0 10 2 2 13 13 13 3 HEAT-like repeat ParcG PF10274.9 OAJ32640.1 - 2.7e-05 24.4 4.3 0.69 10.0 0.0 5.6 4 1 1 6 6 6 1 Parkin co-regulated protein Cnd1 PF12717.7 OAJ32640.1 - 4.9e-05 23.4 3.9 3.9 7.5 0.0 5.5 5 2 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 FAT PF02259.23 OAJ32640.1 - 0.00017 21.0 0.3 0.00017 21.0 0.3 2.5 3 0 0 3 3 3 1 FAT domain DUF3535 PF12054.8 OAJ32640.1 - 0.0026 17.1 0.6 0.72 9.0 0.0 3.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3535) Adaptin_N PF01602.20 OAJ32640.1 - 0.012 14.2 7.9 0.1 11.1 0.2 5.0 4 1 1 5 5 5 0 Adaptin N terminal region VHS PF00790.19 OAJ32640.1 - 0.024 14.5 0.4 19 5.1 0.0 3.9 4 1 1 5 5 5 0 VHS domain Tti2 PF10521.9 OAJ32640.1 - 0.11 12.0 0.6 2.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Tti2 family FdhE PF04216.12 OAJ32640.1 - 0.46 10.3 3.9 2.9 7.7 0.1 3.5 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation Urb2 PF10441.9 OAJ32640.1 - 0.69 9.8 3.2 2.6 8.0 0.0 3.2 3 0 0 3 3 3 0 Urb2/Npa2 family GPP34 PF05719.11 OAJ32641.1 - 4.3e-64 216.3 0.0 5.3e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Peptidase_M24 PF00557.24 OAJ32642.1 - 4.6e-13 49.4 0.0 5.9e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S19e PF01090.19 OAJ32644.1 - 2.7e-53 179.3 0.0 3.1e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SDA1 PF05285.12 OAJ32644.1 - 0.013 14.9 5.8 0.016 14.7 5.8 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 OAJ32644.1 - 0.028 14.2 11.0 0.03 14.0 11.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 OAJ32644.1 - 0.04 14.2 9.7 0.047 14.0 9.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 OAJ32644.1 - 0.075 13.1 4.2 0.089 12.8 4.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 OAJ32644.1 - 3.7 5.6 8.9 3.9 5.6 8.9 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 OAJ32644.1 - 6.5 4.9 8.4 7.3 4.8 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 OAJ32644.1 - 7.7 5.7 17.5 9.2 5.5 17.5 1.1 1 0 0 1 1 1 0 NOA36 protein TFCD_C PF12612.8 OAJ32645.1 - 8.4e-33 113.8 0.0 1.2e-31 110.1 0.0 3.0 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal IFRD PF05004.13 OAJ32645.1 - 0.01 14.9 0.1 0.01 14.9 0.1 4.1 3 2 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 OAJ32645.1 - 0.013 15.7 0.0 0.013 15.7 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat Vac14_Fab1_bd PF12755.7 OAJ32645.1 - 0.015 15.9 0.0 0.19 12.3 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 OAJ32645.1 - 0.015 15.5 0.1 3.6 7.8 0.0 3.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 OAJ32645.1 - 0.031 14.3 0.4 1 9.4 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 OAJ32645.1 - 0.032 14.0 0.0 0.19 11.5 0.0 2.4 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 OAJ32645.1 - 0.032 14.7 0.0 0.032 14.7 0.0 6.6 6 2 2 8 8 8 0 HEAT-like repeat Nefa_Nip30_N PF10187.9 OAJ32646.1 - 1.3e-26 93.0 9.4 2e-26 92.4 9.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 TPX2 PF06886.11 OAJ32646.1 - 2.8 8.2 12.9 1.4 9.2 3.5 3.1 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) Ribosomal_S7 PF00177.21 OAJ32647.1 - 1.5e-29 102.6 0.1 2.9e-29 101.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e HLH PF00010.26 OAJ32648.1 - 6.5e-15 54.8 0.3 1e-14 54.2 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SelP_N PF04592.14 OAJ32648.1 - 0.96 8.8 9.0 1.7 8.0 9.0 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMC_N PF02463.19 OAJ32649.1 - 8.8e-61 205.1 0.0 3.4e-60 203.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 OAJ32649.1 - 5e-28 97.8 0.2 3.3e-27 95.1 0.1 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 OAJ32649.1 - 4.8e-18 66.0 1.1 3.7e-08 33.6 0.0 3.8 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 OAJ32649.1 - 3e-08 33.3 0.2 1.1e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 OAJ32649.1 - 3e-07 30.5 15.4 3e-07 30.5 15.4 4.4 2 2 0 2 2 1 1 AAA ATPase domain SbcCD_C PF13558.6 OAJ32649.1 - 0.0013 18.9 0.0 0.006 16.8 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ATG16 PF08614.11 OAJ32649.1 - 0.0058 16.9 7.1 0.0058 16.9 7.1 8.2 6 1 2 8 8 7 3 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 OAJ32649.1 - 0.073 13.6 0.0 0.073 13.6 0.0 6.0 4 3 0 4 4 3 0 ABC transporter AAA_23 PF13476.6 OAJ32649.1 - 0.076 13.5 104.9 15 6.0 52.9 6.8 3 2 1 4 4 3 0 AAA domain AAA_22 PF13401.6 OAJ32649.1 - 0.77 10.0 5.4 12 6.2 0.0 4.2 3 1 0 3 3 3 0 AAA domain PKI PF02827.16 OAJ32649.1 - 3.2 8.0 8.2 0.68 10.2 0.5 4.0 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Orthopox_F14 PF06076.12 OAJ32649.1 - 4.5 7.6 5.5 26 5.2 0.1 3.3 3 0 0 3 3 3 0 Orthopoxvirus F14 protein Ribosomal_L27A PF00828.19 OAJ32650.1 - 6.1e-23 81.9 0.1 8.5e-23 81.4 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3510 PF12022.8 OAJ32651.1 - 1.3e-10 41.8 0.0 7.2e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 OAJ32651.1 - 1.3e-06 28.5 4.4 0.00087 19.4 0.0 2.8 1 1 1 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.11 OAJ32651.1 - 6.3 7.1 5.7 59 4.0 0.5 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) JAB PF01398.21 OAJ32652.1 - 3.8e-06 26.9 0.0 4.1e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease F-box-like PF12937.7 OAJ32653.1 - 0.026 14.4 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 0 F-box-like DNA_pol_B PF00136.21 OAJ32654.1 - 6.3e-115 384.5 0.0 8.5e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 OAJ32654.1 - 7.5e-51 172.5 0.0 1.3e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 OAJ32654.1 - 1.3e-32 113.3 0.0 3.7e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 OAJ32654.1 - 7.9e-23 80.3 3.3 2e-22 79.0 3.3 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF3246 PF11596.8 OAJ32654.1 - 3.3 7.1 6.6 8.4 5.8 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SH3_1 PF00018.28 OAJ32655.1 - 2e-17 62.5 0.0 2.5e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 OAJ32655.1 - 2.3e-12 46.6 0.0 2.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 OAJ32655.1 - 1.6e-11 43.7 0.0 2.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain Auxin_resp PF06507.13 OAJ32655.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Auxin response factor DUF3104 PF11302.8 OAJ32655.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Aminotran_3 PF00202.21 OAJ32657.1 - 4.6e-108 361.5 0.1 5.6e-108 361.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 OAJ32657.1 - 2.7e-05 23.5 0.0 0.0019 17.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Neisseria_PilC PF05567.11 OAJ32657.1 - 0.058 12.4 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Spc24 PF08286.11 OAJ32658.1 - 4.8e-05 23.5 0.1 0.0049 17.1 0.0 2.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 ABC_membrane_2 PF06472.15 OAJ32658.1 - 0.023 14.1 0.6 0.037 13.4 0.6 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 KELK PF15796.5 OAJ32658.1 - 0.11 12.9 7.7 1.7 9.1 0.2 2.4 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CHGN PF05679.16 OAJ32658.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase LpxK PF02606.14 OAJ32658.1 - 0.19 10.8 0.9 0.29 10.2 0.9 1.3 1 1 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase FapA PF03961.13 OAJ32658.1 - 0.2 10.2 0.4 0.27 9.8 0.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med21 PF11221.8 OAJ32658.1 - 0.97 9.7 4.2 29 4.9 2.0 3.0 3 0 0 3 3 3 0 Subunit 21 of Mediator complex zf-CCCH PF00642.24 OAJ32659.1 - 4e-13 48.9 15.3 1.4e-06 28.0 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 OAJ32659.1 - 0.00071 19.6 9.3 0.0018 18.2 1.9 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 OAJ32659.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 OAJ32659.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.4 2 1 0 2 2 2 0 Torus domain CBFD_NFYB_HMF PF00808.23 OAJ32661.1 - 3.3e-16 59.3 0.1 6.7e-16 58.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 OAJ32661.1 - 0.0038 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Rab_eff_C PF04698.12 OAJ32662.1 - 0.079 11.2 0.2 0.18 10.1 0.2 1.5 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus NUMOD3 PF07460.11 OAJ32663.1 - 0.085 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Proteasome PF00227.26 OAJ32664.1 - 1.2e-58 197.7 0.1 2e-58 197.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 OAJ32664.1 - 1.2e-14 53.7 0.8 3.7e-14 52.1 0.3 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 OAJ32664.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Pet20 PF08692.10 OAJ32665.1 - 0.12 13.0 0.1 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Sigma54_activ_2 PF14532.6 OAJ32665.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Tnp_22_trimer PF17489.2 OAJ32665.1 - 3.5 7.7 7.2 3.1 7.8 5.0 2.0 2 0 0 2 2 2 0 L1 transposable element trimerization domain Methyltransf_16 PF10294.9 OAJ32666.1 - 2.4e-15 56.7 0.0 1.4e-14 54.2 0.0 2.2 1 1 0 1 1 1 1 Lysine methyltransferase DEAD PF00270.29 OAJ32667.1 - 2.3e-26 92.7 0.0 7.3e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 OAJ32667.1 - 6.3e-19 68.5 1.2 2.2e-18 66.8 1.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 OAJ32667.1 - 1.7e-13 50.9 0.3 4.1e-12 46.4 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Mito_carr PF00153.27 OAJ32667.1 - 5.3e-09 35.9 0.1 7.8e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein CDT1 PF08839.11 OAJ32667.1 - 4.4e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 OAJ32667.1 - 5.6e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ox_reductase_C PF08635.10 OAJ32668.1 - 2.4e-77 257.4 0.1 3.8e-77 256.8 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 OAJ32668.1 - 6.4e-25 88.3 0.0 2e-24 86.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 OAJ32668.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RNA_pol_L_2 PF13656.6 OAJ32669.1 - 4.1e-28 96.9 0.0 5.6e-28 96.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 OAJ32669.1 - 1e-08 34.5 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain mit_SMPDase PF14724.6 OAJ32669.1 - 0.12 10.4 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF1707 PF08044.11 OAJ32669.1 - 0.46 10.6 4.7 6.5 6.9 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1707) RRM_1 PF00076.22 OAJ32670.1 - 1.1e-15 57.1 0.1 1.9e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 OAJ32670.1 - 0.0046 17.0 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif efThoc1 PF11957.8 OAJ32671.1 - 1.8e-55 188.6 16.3 3.6e-30 105.1 0.0 5.1 3 1 0 3 3 3 3 THO complex subunit 1 transcription elongation factor CNDH2_C PF16858.5 OAJ32671.1 - 1.3 8.8 25.3 3 7.6 12.5 3.3 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Chorein_N PF12624.7 OAJ32672.1 - 0.23 11.6 2.4 34 4.6 0.0 3.3 1 1 3 4 4 4 0 N-terminal region of Chorein or VPS13 NOA36 PF06524.12 OAJ32672.1 - 0.39 10.0 1.3 0.65 9.3 1.3 1.2 1 0 0 1 1 1 0 NOA36 protein Cornifin PF02389.15 OAJ32672.1 - 6.8 6.9 17.1 0.046 13.9 7.2 2.4 2 1 1 3 3 3 0 Cornifin (SPRR) family Sporozoite_P67 PF05642.11 OAJ32672.1 - 8 4.4 17.0 11 4.0 15.2 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen ubiquitin PF00240.23 OAJ32673.1 - 1e-33 114.9 0.7 1e-33 114.9 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 OAJ32673.1 - 3.3e-26 91.2 0.9 3.3e-26 91.2 0.9 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 OAJ32673.1 - 4.5e-16 58.4 0.8 8e-16 57.6 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 OAJ32673.1 - 6.2e-06 26.6 0.4 0.00014 22.3 0.1 2.6 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 OAJ32673.1 - 0.00057 20.0 0.7 0.0013 18.8 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 OAJ32673.1 - 0.0064 16.4 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 OAJ32673.1 - 0.0074 16.6 0.7 0.013 15.8 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 OAJ32673.1 - 0.0098 16.4 1.1 0.014 15.9 1.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.21 OAJ32673.1 - 0.01 16.1 0.2 0.018 15.3 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 OAJ32673.1 - 0.022 14.8 1.1 6.4 6.9 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Roughex PF06020.11 OAJ32674.1 - 2.3 7.2 7.2 3.7 6.5 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein TPR_1 PF00515.28 OAJ32675.1 - 7.3e-10 38.2 17.3 0.32 10.9 0.0 8.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 OAJ32675.1 - 1.3e-06 28.0 29.5 0.18 12.0 0.1 10.1 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 OAJ32675.1 - 4.7e-06 26.6 2.8 3.4 8.3 0.2 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 OAJ32675.1 - 0.00064 19.4 11.2 5.4 6.8 0.0 7.4 9 0 0 9 9 9 2 TPR repeat TPR_8 PF13181.6 OAJ32675.1 - 0.0025 17.9 17.6 2.4 8.6 0.0 8.6 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.6 OAJ32675.1 - 0.022 15.3 0.2 0.022 15.3 0.2 9.9 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ32675.1 - 0.054 14.0 43.1 0.46 11.0 0.2 9.5 8 2 1 10 10 10 0 Tetratricopeptide repeat TPR_12 PF13424.6 OAJ32675.1 - 0.55 10.6 0.0 0.55 10.6 0.0 8.6 11 0 0 11 11 11 0 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.9 OAJ32676.1 - 3.3e-31 107.8 0.0 5.1e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 OAJ32676.1 - 4.6e-11 42.5 0.0 7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Acyl_transf_3 PF01757.22 OAJ32676.1 - 0.0078 15.3 0.6 0.01 14.9 0.6 1.1 1 0 0 1 1 1 1 Acyltransferase family POP1 PF06978.11 OAJ32677.1 - 2e-23 83.5 18.2 2e-23 83.5 18.2 4.1 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 OAJ32677.1 - 6.6e-15 55.2 3.1 1.5e-14 54.1 0.0 2.8 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T_C PF08669.11 OAJ32677.1 - 0.048 13.6 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Ferlin_C PF16165.5 OAJ32677.1 - 2.8 7.9 13.7 0.22 11.4 0.6 3.3 3 0 0 3 3 3 0 Ferlin C-terminus PPP4R2 PF09184.11 OAJ32677.1 - 8 6.0 8.7 10 5.6 5.9 2.3 2 0 0 2 2 2 0 PPP4R2 TFR_dimer PF04253.15 OAJ32678.1 - 2.2e-15 56.8 0.0 4.3e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ32678.1 - 4.3e-15 55.9 0.0 9.4e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ32678.1 - 4e-11 42.8 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 PA domain Actin PF00022.19 OAJ32679.1 - 3.3e-48 164.3 0.0 4.8e-47 160.5 0.0 2.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 OAJ32679.1 - 0.008 15.0 0.0 0.02 13.7 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein CDC27 PF09507.10 OAJ32679.1 - 0.016 14.6 7.0 0.045 13.1 7.0 1.7 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2457 PF10446.9 OAJ32679.1 - 1.5 7.8 26.4 3.6 6.6 26.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 OAJ32679.1 - 7.6 5.8 20.3 11 5.4 16.5 2.2 2 0 0 2 2 2 0 SDA1 DFRP_C PF16543.5 OAJ32680.1 - 5.9 7.5 10.0 0.46 11.0 0.2 3.5 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 tRNA-synt_2 PF00152.20 OAJ32681.1 - 6e-74 248.9 0.0 7.4e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 OAJ32681.1 - 8.1e-11 41.8 0.0 2.5e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 OAJ32681.1 - 8e-08 32.1 0.0 0.00015 21.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UDPGP PF01704.18 OAJ32682.1 - 2.2e-25 89.1 0.0 8e-15 54.4 0.0 2.3 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase Lipase_3 PF01764.25 OAJ32683.1 - 2.2e-12 47.0 0.0 1e-11 44.8 0.0 2.1 2 1 0 2 2 2 1 Lipase (class 3) Fungal_trans PF04082.18 OAJ32684.1 - 3.4e-07 29.6 7.7 0.0028 16.7 0.0 3.1 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 OAJ32684.1 - 2.6e-05 24.2 8.8 5e-05 23.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.13 OAJ32684.1 - 1.1 9.1 0.0 1.1 9.1 0.0 2.8 3 1 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Ribosomal_S6e PF01092.19 OAJ32685.1 - 5.6e-55 184.7 0.4 9.4e-55 183.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 OAJ32686.1 - 8e-31 105.9 0.4 1.3e-30 105.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 OAJ32686.1 - 1.3e-13 51.0 0.5 1.8e-13 50.5 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 OAJ32686.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain zf-RRN7 PF11781.8 OAJ32688.1 - 1.3 8.8 4.8 0.33 10.7 1.2 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Tyrosinase PF00264.20 OAJ32690.1 - 1.2e-33 117.3 0.2 2e-33 116.6 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF21 PF01595.20 OAJ32691.1 - 1e-36 126.3 0.4 2.3e-36 125.1 0.4 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 OAJ32691.1 - 3.1e-08 33.9 0.1 0.02 15.3 0.1 3.2 3 0 0 3 3 3 2 CBS domain PIN_4 PF13638.6 OAJ32692.1 - 9.9e-19 67.9 2.0 2.1e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 OAJ32692.1 - 2.4e-07 30.6 0.0 1.1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 OAJ32692.1 - 0.0066 16.7 0.2 0.49 10.7 0.0 2.8 2 1 0 2 2 2 1 PIN like domain YL1 PF05764.13 OAJ32692.1 - 0.011 15.9 1.1 0.011 15.9 1.1 2.1 2 0 0 2 2 2 0 YL1 nuclear protein eIF3_subunit PF08597.10 OAJ32692.1 - 0.11 12.4 10.4 0.28 11.1 10.4 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_phi PF04931.13 OAJ32692.1 - 1.3 7.0 7.7 2.2 6.3 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1765 PF08578.10 OAJ32693.1 - 1.6e-26 93.2 1.5 2.6e-26 92.5 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) GATase_5 PF13507.6 OAJ32694.1 - 1.1e-93 313.0 0.0 1.7e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 OAJ32694.1 - 1.2e-39 136.0 4.2 1.4e-25 90.2 0.1 2.6 2 1 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 OAJ32694.1 - 1.5e-30 105.5 0.0 3.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 OAJ32694.1 - 6e-21 74.7 0.0 1.4e-20 73.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain TFR_dimer PF04253.15 OAJ32695.1 - 1.8e-21 76.5 0.1 9.6e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 OAJ32695.1 - 4.8e-16 59.0 0.0 8.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 OAJ32695.1 - 4e-11 42.8 0.0 1e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 PA domain PPR_2 PF13041.6 OAJ32695.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SOBP PF15279.6 OAJ32696.1 - 3.3 8.2 7.6 6.5 7.3 7.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pyr_redox_2 PF07992.14 OAJ32698.1 - 1.7e-43 149.0 2.7 2.2e-43 148.6 2.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 OAJ32698.1 - 1.4e-16 60.2 0.0 3e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 OAJ32698.1 - 1.1e-12 48.3 7.9 4.7e-11 43.1 0.5 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 OAJ32698.1 - 2.9e-07 30.4 0.0 8.6e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 OAJ32698.1 - 0.03 14.9 0.0 0.092 13.3 0.0 1.9 1 0 0 1 1 1 0 Reductase C-terminal K_oxygenase PF13434.6 OAJ32698.1 - 0.091 11.9 0.2 29 3.6 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 OAJ32698.1 - 0.13 11.6 0.2 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FBPase PF00316.20 OAJ32700.1 - 5.6e-74 247.7 0.4 7e-74 247.4 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 OAJ32700.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family AAA PF00004.29 OAJ32701.1 - 5.5e-31 107.7 0.0 1.2e-30 106.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 OAJ32701.1 - 2.1e-07 31.3 0.1 1.2e-06 28.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 OAJ32701.1 - 1.1e-06 29.1 0.0 3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 OAJ32701.1 - 5.9e-06 26.5 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 OAJ32701.1 - 1.8e-05 24.9 0.0 9e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 OAJ32701.1 - 2.4e-05 24.9 0.0 5.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 OAJ32701.1 - 3.2e-05 24.0 0.1 0.016 15.1 0.1 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 OAJ32701.1 - 3.9e-05 23.3 0.1 0.2 11.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain NACHT PF05729.12 OAJ32701.1 - 0.00032 20.6 0.2 0.0029 17.5 0.2 2.2 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 OAJ32701.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 OAJ32701.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 OAJ32701.1 - 0.0023 17.8 1.5 0.0043 16.9 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 OAJ32701.1 - 0.0027 17.5 0.2 0.011 15.5 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 OAJ32701.1 - 0.0028 17.4 0.1 0.0088 15.8 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 OAJ32701.1 - 0.0036 17.7 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 OAJ32701.1 - 0.0036 17.3 0.0 0.008 16.2 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 OAJ32701.1 - 0.0037 17.3 0.1 0.008 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 OAJ32701.1 - 0.0041 16.6 0.0 0.48 9.8 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein Cytidylate_kin PF02224.18 OAJ32701.1 - 0.0045 16.7 0.1 0.0087 15.8 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_28 PF13521.6 OAJ32701.1 - 0.005 17.1 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 OAJ32701.1 - 0.0053 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 OAJ32701.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 OAJ32701.1 - 0.0089 15.2 0.0 0.047 12.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 OAJ32701.1 - 0.018 14.3 0.0 1.1 8.5 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 OAJ32701.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 OAJ32701.1 - 0.024 14.5 0.1 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 OAJ32701.1 - 0.031 13.7 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 OAJ32701.1 - 0.037 14.5 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 OAJ32701.1 - 0.038 14.3 0.0 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 OAJ32701.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 OAJ32701.1 - 0.058 13.8 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 OAJ32701.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DUF2075 PF09848.9 OAJ32701.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 OAJ32701.1 - 0.096 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SPC25 PF06703.11 OAJ32701.1 - 0.097 12.5 0.1 3 7.6 0.0 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CPT PF07931.12 OAJ32701.1 - 0.098 12.5 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 OAJ32701.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 OAJ32701.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation eRF1_1 PF03463.15 OAJ32702.1 - 2.1e-49 166.8 0.0 3.1e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 OAJ32702.1 - 3.7e-22 78.9 0.0 7.1e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 OAJ32702.1 - 3.2e-21 76.0 0.0 4.9e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 tRNA_anti-codon PF01336.25 OAJ32702.1 - 0.12 12.4 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF2407_C PF13373.6 OAJ32703.1 - 3.8e-12 46.6 3.1 7.5e-12 45.6 0.9 2.5 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 OAJ32703.1 - 9.3e-12 45.4 0.6 2.6e-10 40.8 0.2 2.9 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 OAJ32703.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ifi-6-16 PF06140.13 OAJ32704.1 - 2.9e-07 30.3 10.2 4.2e-07 29.8 10.2 1.2 1 0 0 1 1 1 1 Interferon-induced 6-16 family Sugar_tr PF00083.24 OAJ32705.1 - 1.2e-19 70.6 17.3 1.3e-15 57.2 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ32705.1 - 2.5e-11 43.1 33.7 8.8e-11 41.3 33.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S10 PF00450.22 OAJ32707.1 - 5.3e-89 299.5 0.0 1.5e-76 258.5 0.0 2.5 2 1 0 2 2 2 2 Serine carboxypeptidase PQ-loop PF04193.14 OAJ32708.1 - 1e-23 82.9 0.5 2.2e-13 49.7 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat Zn_clus PF00172.18 OAJ32709.1 - 8e-05 22.7 11.6 0.00014 21.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 OAJ32709.1 - 0.39 10.7 24.8 0.095 12.7 14.4 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 OAJ32709.1 - 0.56 8.4 7.4 0.64 8.2 2.0 2.3 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 OAJ32709.1 - 1.5 8.4 7.8 5.4 6.7 0.7 2.9 2 0 0 2 2 2 0 FAM176 family F-actin_cap_A PF01267.17 OAJ32710.1 - 1.7e-69 234.2 0.0 2.5e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TPR_2 PF07719.17 OAJ32712.1 - 3e-07 30.0 0.7 1 9.7 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 OAJ32712.1 - 0.0055 17.4 11.5 2 9.4 0.8 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 OAJ32712.1 - 0.015 16.0 4.5 1 10.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 OAJ32712.1 - 0.027 14.3 0.7 40 4.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 OAJ32712.1 - 0.038 14.2 0.2 76 3.9 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 OAJ32712.1 - 0.089 12.9 1.5 5.8 7.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 OAJ32712.1 - 0.22 12.0 7.4 24 5.5 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Peptidase_C48 PF02902.19 OAJ32713.1 - 7.4e-24 84.8 0.1 2.7e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain KAR9 PF08580.10 OAJ32714.1 - 7.7e-06 24.8 41.5 7.7e-06 24.8 41.5 6.1 2 1 2 4 4 4 1 Yeast cortical protein KAR9 GAS2 PF02187.17 OAJ32714.1 - 0.019 15.0 0.3 0.052 13.6 0.3 1.7 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain KASH_CCD PF14662.6 OAJ32715.1 - 0.0023 17.8 14.3 0.0023 17.8 14.3 2.7 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH RRM_1 PF00076.22 OAJ32716.1 - 1.8e-17 62.9 0.0 2.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 OAJ32716.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 OAJ32716.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 RL domain FeS_assembly_P PF01883.19 OAJ32717.1 - 1e-11 44.8 0.0 2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Sporozoite_P67 PF05642.11 OAJ32717.1 - 0.087 10.9 1.6 0.12 10.5 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Collagen_mid PF15984.5 OAJ32718.1 - 5e-05 23.2 8.4 0.00098 18.9 0.7 2.2 1 1 1 2 2 2 2 Bacterial collagen, middle region Apolipoprotein PF01442.18 OAJ32718.1 - 0.0019 18.1 0.7 0.016 15.1 0.3 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 OAJ32718.1 - 0.0087 16.3 4.2 0.065 13.5 0.7 3.1 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) I_LWEQ PF01608.17 OAJ32718.1 - 0.021 15.1 1.7 0.29 11.4 0.0 2.6 1 1 1 2 2 2 0 I/LWEQ domain ApoLp-III PF07464.11 OAJ32718.1 - 0.024 14.7 0.6 1.4 9.0 0.3 2.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 OAJ32718.1 - 0.041 13.9 1.5 1.1 9.3 0.9 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 OAJ32718.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein IF4E PF01652.18 OAJ32719.1 - 4.8e-45 153.2 0.0 6.5e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cation_efflux PF01545.21 OAJ32720.1 - 5.1e-40 137.3 7.7 5.2e-39 134.0 7.7 2.0 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 OAJ32720.1 - 1.4e-07 31.6 0.3 5.7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter LEA_2 PF03168.13 OAJ32721.1 - 0.11 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein T2SSF PF00482.23 OAJ32721.1 - 1.1 9.2 3.1 0.57 10.2 0.3 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Glyco_hydro_5_C PF18564.1 OAJ32722.1 - 6.2e-11 42.7 0.0 1.3e-08 35.2 0.0 2.8 3 0 0 3 3 3 2 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 OAJ32722.1 - 6.8e-09 35.6 0.0 9.4e-08 31.8 0.1 2.4 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Acyltransferase PF01553.21 OAJ32723.1 - 5.1e-17 61.8 0.1 8e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase Peptidase_M20 PF01546.28 OAJ32724.1 - 8.2e-18 64.8 3.3 5.7e-17 62.1 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 OAJ32724.1 - 3.7e-11 43.4 14.2 0.00034 21.3 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.14 OAJ32724.1 - 2.5e-08 33.8 0.0 6.6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 OAJ32724.1 - 0.00025 21.3 0.2 0.27 11.6 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BSP_II PF05432.11 OAJ32724.1 - 0.76 9.4 5.1 1.6 8.3 5.1 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Macoilin PF09726.9 OAJ32724.1 - 1.1 7.7 4.0 1.7 7.1 4.0 1.2 1 0 0 1 1 1 0 Macoilin family VIT1 PF01988.19 OAJ32725.1 - 2.7e-59 200.7 4.5 3.6e-59 200.2 4.5 1.2 1 0 0 1 1 1 1 VIT family Chromate_transp PF02417.15 OAJ32726.1 - 3.3e-58 196.3 35.7 3e-34 118.4 11.2 2.4 3 0 0 3 3 3 2 Chromate transporter Sugar_tr PF00083.24 OAJ32727.1 - 2.4e-29 102.5 19.6 2.8e-19 69.3 6.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 OAJ32727.1 - 5.3e-14 51.9 43.1 5.3e-09 35.5 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 OAJ32727.1 - 0.32 9.2 1.2 0.52 8.5 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2207 PF09972.9 OAJ32727.1 - 2.8 6.6 4.4 7.2 5.2 0.0 2.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) RNase_T PF00929.24 OAJ32728.1 - 2.6e-10 41.1 0.1 3.1e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Exonuclease PFU PF09070.11 OAJ32729.1 - 3.9e-44 149.5 0.1 7.1e-44 148.7 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 OAJ32729.1 - 6.4e-43 147.0 1.1 8.8e-43 146.5 1.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 OAJ32729.1 - 1.5e-29 101.6 13.7 1.6e-05 25.6 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.6 OAJ32729.1 - 0.61 10.7 5.3 50 4.6 0.1 4.5 4 1 1 5 5 5 0 PQQ-like domain ThiF PF00899.21 OAJ32730.1 - 2.8e-104 347.8 0.0 7.5e-71 238.3 0.0 2.0 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 OAJ32730.1 - 1.5e-91 306.8 0.2 2.6e-91 306.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 OAJ32730.1 - 2.5e-34 117.3 0.3 5.4e-34 116.2 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 OAJ32730.1 - 5.7e-29 100.7 0.0 1.2e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 OAJ32730.1 - 3.7e-25 87.9 0.2 8.5e-25 86.7 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Pyr_redox PF00070.27 OAJ32730.1 - 0.46 11.1 2.3 41 4.8 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RNase_T PF00929.24 OAJ32731.1 - 7.2e-10 39.7 0.0 8.5e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF4363 PF14276.6 OAJ32731.1 - 0.089 12.9 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_controversa-ASM164504v1/GCA_001645045.1_ASM164504v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_controversa-ASM164504v1/GCA_001645045.1_ASM164504v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_controversa-ASM164504v1/GCA_001645045.1_ASM164504v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tilletia_controversa-ASM164504v1/GCA_001645045.1_ASM164504v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:26:13 2019 # [ok]